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1
Functional Dichotomy within the Vomeronasal System: Distinct Zones of Neuronal Activity in the Accessory Olfactory Bulb

for identifying pheromone molecules. Key words: vomeronasal organ; accessory olfactory bulb; pheromones; sex in the Accessory Olfactory Bulb Correlate with Sex-Specific Behaviors Arvind Kumar, Carol A. Dudley, and Robert L or accessory ...

E-print Network

2
The accessory olfactory bulb of the mink, Mustela vison: a morphological and lectin histochemical study.
1998-10-01

The distribution of binding sites for the lectins Ulex europaeus agglutinin I, Soybean agglutinin, Bandeiraea simplicifolia agglutinin I-isolectin B4, and Vicia villosa agglutinin in the mink olfactory bulb was investigated. All lectins except Ulex europaeus agglutinin I bound exclusively and systematically to a single area of the ...

PubMed

3
The efferent connections of the olfactory bulb and accessory olfactory bulb in the snakes, Thamnophis sirtalis and Thamnophis radix.
1976-10-01

The efferent connections of the olfactory bulb and accessory olfactory bulb of two species of garter snakes, Thamnophis sirtalis and T. radix were studied with experimental anterograde degeneration techniques. Axons of cells located in the olfactory ...

PubMed

4
Projections of olfactory bulbs to the olfactory and vomeronasal cortices.
2008-10-01

Projections from the olfactory bulbs have been traditionally described as 'nontopographically organized'. Olfactory and vomeronasal projections have been reported to reach nonoverlapping cortical areas. Four receptor expression zones have been described in the olfactory epithelium, maintained in the main ...

PubMed

5
Efferents and centrifugal afferents of the main and accessory olfactory bulbs in the snake Thamnophis sirtalis.
1998-01-01

This study reinvestigates the efferent projections of the main and accessory olfactory bulbs and describes for the first time the centrifugal projections to the main and accessory olfactory bulbs in the snake Thamnophis sirtalis, using the intraaxonal transport of the ...

PubMed

6
The prenatal maturity of the accessory olfactory bulb in pigs.
2004-01-01

The morphological development of the accessory olfactory bulb of the fetal pig was studied by classical and histo-chemical methods, and the vomeronasal organ and nasal septum were studied histochemically. Specimens were obtained from an abattoir and their ages estimated from their crown-to-rump length. The ...

PubMed

7
Developmental changes in cytochrome oxidase histochemistry in the main and accessory olfactory bulbs of embryonic and neonatal garter snakes (Thamnophis sirtalis spp.).
1993-12-01

Developmental studies examining the changes in oxidative metabolic activity are useful for understanding how and if the vomeronasal and olfactory systems respond to stimulation during embryogenesis. Garter snakes are good candidates for examining the potential functionality of the vomeronasal system in utero. In adult garter snakes, the vomeronasal system mediates many ...

PubMed

8
Organisation and chemical neuroanatomy of the African elephant (Loxodonta africana) olfactory bulb.
2011-04-11

The olfactory system of mammals can be divided into a main and accessory olfactory system with initial processing for each system occurring in the olfactory bulb. The main and accessory olfactory bulbs have similar structural ...

PubMed

9
Lectin Histochemical Study on the Olfactory Bulb of the Newt, Cynops pyrrhogaster.
2011-05-19

With 2 figures and 2 tables SUMMARY: The function and/or morphological features of the vomeronasal olfactory system remain unclear in aquatic animals, although the system appeared first in urodeles based on phylogenic data. We examined the lectin binding patterns in the olfactory bulb of a semi-aquatic urodele, the Japanese red-bellied ...

PubMed

10
Regeneration of vomeronasal nerves into the main olfactory bulb in the mouse.
1981-07-20

After surgical section of the vomeronasal nerves the neurosensory cells in the vomeronasal epithelium die. Electron microscopy has been used to demonstrate that their axons, and synaptic terminals in the accessory olfactory bulb degenerate and are removed by phagocytic astroglia. The vacated postsynaptic sites in the ...

PubMed

11
Expression of connexin 57 in the olfactory epithelium and olfactory bulb.
2011-08-01

In the visual system, deletion of connexin 57 (Cx57) reduces gap junction coupling among horizontal cells and results in smaller receptive fields. To explore potential functions of Cx57 in olfaction, in situ hybridization and immunohistochemistry methods were used to investigate expression of Cx57 in the olfactory epithelium and olfactory ...

PubMed

12
Lectin binding patterns in the vomeronasal organ and accessory olfactory bulb of the rat.
1998-10-01

A number of previous studies have indicated that lectin histochemistry is an obvious choice for characterizing the vomeronasal system. However, apparently inconsistent results have been obtained: notably, the affinity with which various lectins bind to the accessory olfactory bulb varies among taxa, even considering closely related ...

PubMed

13
99:2021-2025, 2008. First published Feb 6, 2008; doi:10.1152/jn.01324.2007J Neurophysiol David H. Gire and Nathan E. Schoppa

representation of the spatial code for odors after olfactory classical conditioning; memory trace formation. Yuan Q, Harley CW, McLean JH, Knopfel T. Optical imaging of odor preference memory in the rat olfactory Cells of the Accessory Olfactory Bulb Excitatory Actions of Noradrenaline and ...

E-print Network

14
Paced-Mating Increases the Number of Adult New Born Cells in the Internal Cellular (Granular) Layer of the Accessory Olfactory Bulb
2011-05-27

The continuous production and addition of new neurons during life in the olfactory bulb is well accepted and has been extensively studied in rodents. This process could allow the animals to adapt to a changing environment. Olfactory neurogenesis begins in the subventricular zone where stem cells proliferate and give rise to young ...

PubMed Central

15
Distinct intrinsic membrane properties determine differential information processing between main and accessory olfactory bulb mitral cells.
2011-05-26

Most mammals rely on semiochemicals, such as pheromones, to mediate their social interactions. Recent studies found that semiochemicals are perceived by at least two distinct chemosensory systems: the main and accessory olfactory systems, which share many molecular, cellular, and anatomical features. Nevertheless, the division of labor between these ...

PubMed

16
Subdivision of the accessory olfactory bulb in the Japanese common toad, Bufo japonicus, revealed by lectin histochemical analysis.
2006-03-31

Lectin binding patterns in the olfactory bulb of the Japanese common toad, Bufo japonicus, were examined using 21 types of lectin. Ten out of 21 lectins, WGA, s-WGA, LEL, STL, DBA, VVA, SJA, RCA-I, PNA, and PHA-L, stained the olfactory nerve, the glomeruli in the main olfactory bulb (MOB), the ...

PubMed

17
RESPONSES OF SINGLE NEURONS IN THE OLFACTORY ...
1966-01-26

... were made of the activity of single neurons in the olfactory bulbs of anesthetized ... produced an alteration in firing rate in some olfactory bulb neurons ...

DTIC Science & Technology

18
The development of the olfactory organs in newly hatched monotremes and neonate marsupials.
2011-05-17

Olfactory cues are thought to play a crucial role in the detection of the milk source at birth in mammals. It has been shown that a marsupial, the tammar wallaby, can detect olfactory cues from its mother's pouch at birth. This study investigates whether the main olfactory and accessory ...

PubMed

19
Cytochrome oxidase activity in the olfactory system of staggerer mutant mice.
2001-08-10

The staggerer mutation is characterized by the disruption of a single recessive gene encoding for the nuclear hormone receptor RORalpha. In addition to the well-studied gene expression in the cerebellum causing massive primary Purkinje cell loss, the RORalpha gene is also expressed in the thalamus and the olfactory bulb. A quantitative histochemical study ...

PubMed

20
Accessory olfactory bulb function is modulated by input from the main olfactory epithelium.
2010-03-08

Although it is now established that sensory neurons in both the main olfactory epithelium and the vomeronasal organ may be activated by both general and pheromonal odorants, it remains unclear what initiates sampling by the vomeronasal organ. Anterograde transport of wheat germ agglutinin-horseradish peroxidase was used to determine that adequate intranasal syringing with zinc ...

PubMed

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21
Induction of an Olfactory Memory by the Activation of a Metabotropic Glutamate Receptor
1994-07-01

Female mice form an olfactory memory of male pheromones at mating; exposure to the pheromones of a strange male after that mating will block pregnancy. The formation of this memory is mediated by the accessory olfactory system, in which an increase in norepinephrine after mating reduces inhibitory transmission of ?-aminobutyric acid ...

NASA Astrophysics Data System (ADS)

22
Wiring Olfaction: The Cellular and Molecular Mechanisms that Guide the Development of Synaptic Connections from the Nose to the Cortex
2009-12-04

Within the central nervous system, the olfactory system fascinates by its developmental and physiological particularities, and is one of the most studied models to understand the mechanisms underlying the guidance of growing axons to their appropriate targets. A constellation of contact-mediated (laminins, CAMs, ephrins, etc.) and secreted mechanisms (semaphorins, slits, ...

PubMed Central

23
This article was originally published in the Encyclopedia of Animal Behavior published by Elsevier, and the attached copy is provided by Elsevier for the

with the differential development of the accessory sex structures during embryogenesis as described by Alfred Jost a few that are caused by the `organizing effect of perinatal androgen' and that can be related to sex differences Male circuit Female circuit Accessory olfactory bulb Vomeronasal organ Female Male mPOA ...

E-print Network

24
ENCYCLOPEDIA OF ANIMAL BEHAVIOR - CONTRIBUTORS' INSTRUCTIONS PROOFREADING

the analogy with the differential development of the accessory sex structures during embryogenesis this Developmental Organization fol- lowed by Adult Activation paradigm, one tends to view sex differences in brain Female circuit Accessory olfactory bulb Vomeronasal organ Female Male mPOA mPOA VMN VMN Receptivity

E-print Network

25
Neurogenesis in the Hippocampus and Olfactory Bulb
2009-04-14

Professor Ronald McKay explains that neurons in the hippocampus and olfactory bulb are unique in that they are produced throughout life. This is known as neurogenesis.

NSDL National Science Digital Library

26
Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules.
2004-11-15

The projection neurons in the olfactory bulb (mitral and tufted cells) send axons through the lateral olfactory tract (LOT) onto several structures of the olfactory cortex. However, little is known of the molecular and cellular mechanisms underlying establishment of functional connectivity from the ...

PubMed

27
Studies in Neural Networks
2011-05-14

... [6]. We then turned to modeling the olfactory bulb, the first stage of olfactory' information processing in vertebrates. The ...

DTIC Science & Technology

28
Development of the vomeronasal receptor epithelium and the accessory olfactory bulb in sheep.
2003-08-01

The morphological development of the vomeronasal organ (VNO) and accessory olfactory bulb (AOB) of the sheep from anlage to birth were studied by classical and histochemical methods using embryos and fetuses obtained from an abattoir with ages estimated from crown-to-rump length. Both VNO and AOB developed in a biologically logical ...

PubMed

29
Lungfishes, Like Tetrapods, Possess a Vomeronasal System
2010-09-01

The vomeronasal system (VNS) is an accessory olfactory system that in tetrapod vertebrates is composed of specific receptor neurons in the nasal organ and a set of centers in the forebrain that receive and relay the information consecutively towards the hypothalamus. Thus, only in tetrapods the VNS comprises a discrete vomeronasal (Jacobson's) organ, which ...

PubMed Central

30
[How is the sense of smell connected? Cellular and molecular mechanisms guiding the development of the synaptic connections from the nose to the cortex (II)].
2011-05-01

As discussed in the first part of this review, the development of the olfactory system offers a series of fascinating peculiarities that make it one of the models that has been most widely studied in order to reach an understanding of the mechanisms involved in the development of the nervous system. In the first part we reviewed the different mechanisms based on contact ...

PubMed

31
Afferent and efferent connections of the nucleus sphericus in the snake Thamnophis sirtalis: convergence of olfactory and vomeronasal information in the lateral cortex and the amygdala.
1997-09-01

This paper is an account of the afferent and efferent projections of the nucleus sphericus (NS), which is the major secondary vomeronasal structure in the brain of the snake Thamnophis sirtalis. There are four major efferent pathways from the NS: 1) a bilateral projection that courses, surrounding the accessory olfactory tract, and innervates several ...

PubMed

32
Tracing odor-induced activation in the olfactory bulbs of mice using manganese-enhanced magnetic resonance imaging.
2002-06-01

Ithas previously been demonstrated that it is possible to map active regions of the brain using MRI relying on the fact that Mn(2+) ion enters excitable cells through voltage-gated calcium channels and is an excellent relaxation agent. In addition, Mn(2+) has been shown to trace neuronal connections in the mouse olfactory and visual systems, enabling MRI neuronal tract ...

PubMed

33
Localization of 5-HT2A receptor mRNA by in situ hybridization in the olfactory bulb of the postnatal rat.
1995-03-13

The olfactory bulb receives a dense serotonergic input and appears to require serotonergic input in early olfactory associational learning. However, it is not known which cell types receive the serotonergic input or whether the cells express markers for the input throughout life. These issues need resolution in order for the mechanisms ...

PubMed

34
Comparative anatomy of the vomeronasal organ complex in bats.
1976-12-01

The morphology of the vomeronasal organ complex was histologically described in eight out of fourteen chiropteran species investigated. Of the six families examined, all except the family Pteropodidae (suborder Megachiroptera) were found to have at least one member possessing the organ. The organ is best developed in phyllostomatids. It is absent in vespertilionids (including a Myotis embryo) ...

PubMed Central

35
Development of the olfactory system in a wallaby (Macropus eugenii).
2008-03-06

We used carbocyanine dye tracing techniques in conjunction with hematoxylin and eosin staining, immunohistochemistry for GAP-43, and tritiated thymidine autoradiography to examine the development of the olfactory pathways in early pouch young tammar wallabies (Macropus eugenii). The overarching aim was to test the hypothesis that the olfactory system of ...

PubMed

36
Role of Centrifugal Projections to the Olfactory Bulb in Olfactory Processing
2005-12-01

While there is evidence that feedback projections from cortical and neuromodulatory structures to the olfactory bulb are crucial for maintaining the oscillatory dynamics of olfactory bulb processing, it is not clear how changes in dynamics are related to odor perception. Using electrical lesions of the ...

ERIC Educational Resources Information Center

37
Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb.
2009-11-11

The ability of sensory systems to detect and process information from the environment relies on the elaboration of precise connections between sensory neurons in the periphery and second order neurons in the CNS. In mice, the accessory olfactory system is thought to regulate a wide variety of social and sexual behaviors. The expression of the Slit ...

PubMed

38
Vasopressin and social odor processing in the olfactory bulb and anterior olfactory nucleus.
2011-03-01

Central vasopressin facilitates social recognition and modulates numerous complex social behaviors in mammals, including parental behavior, aggression, affiliation, and pair-bonding. In rodents, social interactions are primarily mediated by the exchange of olfactory information, and there is evidence that vasopressin signaling is important in brain areas where ...

PubMed

39
Numbers of Olfactory Receptor Cells and Fine Structure of Olfactory Nerves in Various Birds

... anatomically that many kinds of birds have large olfactory bulbs. The distribution pattern of the olfactory mucosa in ... cell, has one unmyelinated axon extending to the olfactory bulb. It has already be...

NBII National Biological Information Infrastructure

40
Distinct axonal projections from two types of olfactory receptor neurons in the middle chamber epithelium of Xenopus laevis.
2011-09-22

Most vertebrates have two olfactory organs, the olfactory epithelium (OE) and the vomeronasal organ. African clawed frog, Xenopus laevis, which spends their entire life in water, have three types of olfactory sensory epithelia: the OE, the middle chamber epithelium (MCE) and the vomeronasal epithelium (VNE). The axons from these ...

PubMed

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41
www.sciencemag.org SCIENCE VOL 299 21 FEBRUARY 2003 CREDITS:(TOPTOBOTTOM)APPHOTO;MINMINLUOANDLAWRENCEKATZ

in the accessory olfactory bulb (AOB) of mice as they sniff another mouse, the re- searchers have discovered neurons that vary their activity in response to the sex and ge- netic strain of the sniffee. This suggests are detected by re- ceptors in a small, cigar-shaped cavity at the back of the nose, the vomeronasal organ (VNO

E-print Network

42
The role of neurogenesis in olfaction-dependent behaviors.
2011-05-01

Newly born neurons continuously migrate into the main and accessory olfactory bulbs and modulate the output of projection neurons. Despite some contradictory results, it is becoming clear that these newly born neurons play an important role in the response to some odorant cues. In this minireview, we discuss the recent findings ...

PubMed

43
Journal of Neurocytology 34, 135�147 (2005) The vomeronasal organ of greater bushbabies

. Y. (2004) Sexual dimorphism of the vomeronasal organ and the accessory olfactory bulbJournal of Neurocytology 34, 135�147 (2005) The vomeronasal organ of greater bushbabies (Otolemur spp.): Species, sex, and age differences TIMOTHY D. SMITH1,2, , KUNWAR P. BHATNAGAR3 , ANNE M. BURROWS

E-print Network

44
Encoding Pheromonal Signals in the Accessory Olfactory Bulb of

, these putative AOB mitral cells were activated only after test animals directly con- tacted and actively stimulus animals had no effect on the cell's firing rate. Of 34 units for which at least four stimulus trials of initial presentation of stimulus animals to 43 cells, significant inhibito- ry responses were

E-print Network

45
Molecular Physiology of Olfaction.
1989-01-01

Olfactory reception is mediated by olfactory receptor cells located in the olfactory epithelium. These cells are bipolar neurons that extend a dendrite toward the nasal lumen and an axon toward the olfactory bulb in the brain. The dendrite possesses a gro...

National Technical Information Service (NTIS)

46
Dissection of the Hemispheres - Olfactory System.
1994-01-01

The report demonstrates by dissection the olfactory bulb and tract, the medial and lateral olfactory stria, and the points of termination o f the olfactory tract within the telencephalan.

National Technical Information Service (NTIS)

47
Cytoarchitecture of the accessory olfactory bulb in the salamander Plethodon shermani.
2008-04-27

Plethodontid terrestrial salamanders are emerging models in the study of the evolution of chemical communication in vertebrates. Their vomeronasal system is well defined. It comprises sensory neurons in the epithelium of the vomeronasal organ, whose axons form the vomeronasal nerve projecting to the accessory olfactory bulb (AOB), ...

PubMed

48
Development of the olfactory system in turbot (Psetta maxima L.).
2011-02-01

We have examined the histogenesis of the olfactory system during turbot development using histological and immunohistochemical methods. Proliferating cell nuclear antigen (PCNA) immunohistochemistry was used to detect dividing cells, whereas calretinin (CR) immunohistochemistry was used to distinguish some neuronal components of the olfactory system. ...

PubMed

49
Afferent and efferent connections of the cortical and medial nuclei of the amygdala in sheep.
2008-09-12

The cortical (CoA) and the medial (MeA) nuclei of the amygdala are involved in the processing of olfactory information relevant to social recognition in the ewe. To better understand the neural pathways responsible for these effects, the connections of both CoA and MeA with the telencephalic and diencephalic regions were studied by injecting an anterograde ...

PubMed

50
A centrifugal pathway to the mouse accessory olfactory bulb from the medial amygdala conveys gender-specific volatile pheromonal signals
2008-12-11

We previously found that female mice exhibited Fos responses in the accessory olfactory bulb (AOB) after exposure to volatile opposite-, but not same-sex, urinary odours. This effect was eliminated by lesioning the main olfactory epithelium, raising the possibility that the AOB receives information about gender via ...

PubMed Central

51
A centrifugal pathway to the mouse accessory olfactory bulb from the medial amygdala conveys gender-specific volatile pheromonal signals.
2008-12-11

We previously found that female mice exhibited Fos responses in the accessory olfactory bulb (AOB) after exposure to volatile opposite-sex, but not same-sex, urinary odours. This effect was eliminated by lesioning the main olfactory epithelium, raising the possibility that the AOB receives information about gender ...

PubMed

52
A direct main olfactory bulb projection to the 'vomeronasal' amygdala in female mice selectively responds to volatile pheromones from males.
2009-01-28

The main olfactory system, like the accessory olfactory system, responds to pheromones involved in social communication. Whereas pheromones detected by the accessory system are transmitted to the hypothalamus via the medial ('vomeronasal') amygdala, the pathway by which pheromones are detected and transmitted by ...

PubMed

53
Different importance of the volatile and non-volatile fractions of an olfactory signature for individual social recognition in rats versus mice and short-term versus long-term memory.
2010-10-01

When tested in the olfactory cued social recognition/discrimination test, rats and mice differ in their retention of a recognition memory for a previously encountered conspecific juvenile: Rats are able to recognize a given juvenile for approximately 45 min only whereas mice show not only short-term, but also long-term recognition memory (? 24 h). Here we modified the social ...

PubMed

54
Neurogenesis and the Olfactory Bulb
2009-04-14

Professor Pierre Lledo explains that the olfactory bulb is a primary site of neurogenesis - one of the few areas in the brain where new neurons are generated throughout life.

NSDL National Science Digital Library

55
NASA Technical Reports Server - Olfactory bulb removal - Effects ...

Olfactory bulb removal effects on uptake decline of telencephalic norepinephrine , noting use for mapping adrenergic pathways.

NASA Website

56
NASA Technical Reports Server - Olfactory bulb removal - Effects ...

Title: Olfactory bulb removal - Effects on brain norepinephrine. No Digital Version Available: Go to Tips on Ordering. Author: Heimer, L.; Pohorecky, L. A.; ...

NASA Website

57
Rapid activation of phosphorylated mitogen-activated protein kinase after sexual stimulation in male mice.
2011-04-20

We mapped cells immunoreactive for the phosphorylated form (p44/p42) of the mitogen-activated protein kinase (pMAPK--also known as ERK1/2) in the brain of male mice after exposure to female olfactory cues or after the display of male copulatory behaviors. Exposure to soiled bedding from estrous females or the display of coital behaviors rapidly (within 10 min) induced MAPK ...

PubMed

58
Different profiles of main and accessory olfactory bulb mitral/tufted cell projections revealed in mice using an anterograde tracer and a whole-mount, flattened cortex preparation.
2010-12-21

A whole-mount, flattened cortex preparation was developed to compare profiles of axonal projections from main olfactory bulb (MOB) and accessory olfactory bulb (AOB) mitral and tufted (M/T) cells. After injections of the anterograde tracer, Phaseolus vulgaris leucoagglutinin, mapping of labeled ...

PubMed

59
Representation and transformation of sensory information in the mouse accessory olfactory system
2010-05-09

In mice, nonvolatile social cues are detected and analyzed by the accessory olfactory system (AOS). Here we provide a first view of information processing in the AOS with respect to individual chemical cues. 12 sulfated steroids, recently-discovered mouse AOS ligands, caused widespread activity among vomeronasal sensory neurons (VSNs), yet VSN responses ...

PubMed Central

60
Olfactory mediation of maternal behavior in selected mammalian species.
2008-12-25

The aim of this review is to show how olfaction is a sensory modality of singular importance for the fine adjustment of early mother-infant interactions. While the precise role of maternal olfaction varies from one species to another, olfactory cues are in fact used in various aspects of parental care. Not only do infantile odors become very potent stimuli allowing the normal ...

PubMed

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61
The olfactory bulbs in Alzheimer's disease.
1984-01-01

The olfactory bulbs have been examined in patients with Alzheimer's disease and compared with those in elderly undemented and younger undemented control patients. In Alzheimer's disease neurofibrillary tangles were found in the anterior olfactory nucleus but not elsewhere in the olfactory bulb. ...

PubMed Central

62
The Source of Spontaneous Activity in the Main Olfactory Bulb of the Rat
2011-08-30

IntroductionIn vivo, most neurons in the main olfactory bulb exhibit robust spontaneous activity. This paper tests the hypothesis that spontaneous activity in olfactory receptor neurons drives much of the spontaneous activity in mitral and tufted cells via excitatory synapses.MethodsSingle units were recorded in vivo from the main ...

PubMed Central

63
Social Recognition Memory Requires Two Stages of Protein Synthesis in Mice
2005-07-01

Olfactory recognition memory was tested in adult male mice using a social discrimination task. The testing was conducted to begin to characterize the role of protein synthesis and the specific brain regions associated with activity in this task. Long-term olfactory recognition memory was blocked when the protein synthesis inhibitor anisomycin was injected ...

ERIC Educational Resources Information Center

64
Higher Olfactory Centres.
1970-01-01

Evidence concerning the terminal distribution of the olfactory tract in the prepyriform cortex is reviewed. Direct projections from olfactory bulb to hypothalamic areas have not been confirmed in recent anatomical studies. On the other hand, physiological...

National Technical Information Service (NTIS)

65
Brain processing of the mammary pheromone in newborn rabbits.
2011-09-12

Chemosignals strongly contribute to social interactions in mammals, including mother-young relationships. In the European rabbit, a volatile compound emitted by lactating females in milk, the 2-methylbut-2-enal, has been isolated. Carrying the properties of a pheromone, in particular the spontaneous ability to release critical sucking-related movements in newborns, it has been called the mammary ...

PubMed

66
Structure and diversity in mammalian accessory olfactory bulb.
1998-12-15

The accessory olfactory bulb (AOB) is the first neural integrative center for the olfactory-like vomeronasal sensory system. In this article, we first briefly present an overview of vomeronasal system organization and review the history of the discovery of mammalian AOB. Next, we briefly review the evolution of the ...

PubMed

67
Comparative morphology of the accessory olfactory bulb in bats.
1980-03-01

Bouin-perfused brains of 148 bats (76 species, 48 genera, 8 families) were examined in serial sections for the presence of an accessory olfactory bulb. A moderate to well developed AOB was identified in 26 species. However, absence of an AOB in a particular species does not preclude its presence in some other species of that genus. ...

PubMed Central

68
High convergence of olfactory and vomeronasal influence in the telencephalon of the terrestrial salamander Plethodon shermani.
2010-12-20

Previous work suggested that the telencephalic pathways of the main olfactory and vomeronasal systems of vertebrates are mostly isolated from each other, with the possible exception of convergence of the two systems into a small part of the olfactory amygdala. We tested the hypothesis of convergence between the main olfactory and ...

PubMed

69
The Development of a Mathematical Description of the ...
1991-01-16

... Title : The Development of a Mathematical Description of the Olfactory Bulb, Validated with Intracellular and Voltage-Sensitive Dye Recordings. ...

DTIC Science & Technology

70
Information Processing in the Outer Retina
1991-04-18

... In fact Shepherd claims a correspondence between the retina and the olfactory bulb[16]. If this correspondence Is correct ...

DTIC Science & Technology

71
Dilation of the olfactory bulb cavity concurrent with hydrocephalus in four small breed dogs
2009-06-11

Four small breed dogs were admitted with seizures. Magnetic resonance imaging (MRI) of the brain revealed dilation of the olfactory bulb cavity as well as enlargement of the lateral ventricles. These findings demonstrate that dilation of the olfactory bulb cavity can occur concurrent with hydrocephalus. This is the ...

PubMed Central

72
In vivo vomeronasal stimulation reveals sensory encoding of conspecific and allospecific cues by the mouse accessory olfactory bulb
2010-03-16

The rodent vomeronasal system plays a critical role in mediating pheromone-evoked social and sexual behaviors. Recent studies of the anatomical and molecular architecture of the vomeronasal organ (VNO) and of its synaptic target, the accessory olfactory bulb (AOB), have suggested that unique features underlie vomeronasal sensory ...

PubMed Central

73
The risk of extrapolation in neuroanatomy: the case of the Mammalian vomeronasal system.
2009-10-30

The sense of smell plays a crucial role in mammalian social and sexual behaviour, identification of food, and detection of predators. Nevertheless, mammals vary in their olfactory ability. One reason for this concerns the degree of development of their pars basalis rhinencephali, an anatomical feature that has been considered in classifying this group of animals as ...

PubMed

74
The Risk of Extrapolation in Neuroanatomy: The Case of the Mammalian Vomeronasal System
2009-10-30

The sense of smell plays a crucial role in mammalian social and sexual behaviour, identification of food, and detection of predators. Nevertheless, mammals vary in their olfactory ability. One reason for this concerns the degree of development of their pars basalis rhinencephali, an anatomical feature that has been considered in classifying this group of animals as ...

PubMed Central

75
Involvement of G?(olf) -expressing neurons in the vomeronasal system of Bufo japonicus.
2011-11-01

Most terrestrial vertebrates possess anatomically distinct olfactory organs: the olfactory epithelium (OE) and the vomeronasal organ (VNO). In rodents, olfactory receptors coupled to G?(olf) are expressed in the OE, whereas vomeronasal receptors type 1 (V1R) and vomeronasal receptors type 2 (V2R), coupled to G?(i2) and G?(o) , ...

PubMed

76
Thallium transport and the evaluation of olfactory nerve connectivity between the nasal cavity and olfactory bulb.
2007-09-27

Little is known regarding how alkali metal ions are transported in the olfactory nerve following their intranasal administration. In this study, we show that an alkali metal ion, thallium is transported in the olfactory nerve fibers to the olfactory bulb in mice. The olfactory nerve fibers of ...

PubMed

77
Ontogenic Development of Three GnRH Systems in the Brain of a Pleuronectiform Fish, Barfin Flounder

... the transitional area between the olfactory nerve and olfactory bulb and the terminal nerve ganglion on Day 28. ... TN and the ventromedial part of the rostral olfactory bulbs, in the MT, and in the POA, ...

NBII National Biological Information Infrastructure

78
Olfactory neuroscience: beyond the bulb.
2011-06-01

High-resolution tracing of projections from the olfactory bulb to its cortical targets revealed coarse topography and stereotopy in some areas but highly distributed, combinatorial connectivity in others. These results provide a basis for understanding innate and associative olfactory processing and perception. PMID:21640905

PubMed

79
Homology of the �Ethmoid Complex� of Tyrannosaurids and its Implications for the Reconstruction of the Olfactory ...

... for the median septum and dorsal plate. The olfactory bulbs of nonavian theropods were housed within the sphenethmoid, which restricted the maximum size of the olfactory bulbs to a size smaller than the ce...

NBII National Biological Information Infrastructure

80
Olfactory Bulb Response of Rabbit
1961-03-01

An approach to understanding the properties of dendrites is to record the response of the olfactory bulb where the dendrites of mitral cells form the glomeruli. After the stimulations of the bulb and nasal mucosa, the responses appear different, but they are fundamentally composed of three successive potentials, suggesting that the ...

NASA Astrophysics Data System (ADS)

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81
Heterogeneity in the accessory olfactory system.
1998-08-01

The mammalian accessory olfactory bulb (AOB) is chemoarchitecturally heterogeneous in that it stains differentially with a number of markers; the receptor cells that project to the AOB are similarly heterogeneous. What is the significance of this heterogeneity? We have found that the AOB of the gray, short-tailed opossum, Monodelphis ...

PubMed

82
A descriptive and comparative lectin histochemical study of the vomeronasal system in pigs and sheep
2000-01-01

The accessory olfactory bulb (AOB) is the primary target of the sensory epithelium of the vomeronasal organ (VNO), and thus constitutes a fundamental component of the accessory olfactory system, which is involved in responses to behaviour-related olfactory stimuli. In this ...

PubMed Central

83
Efferent control of stimulus access to the hamster vomeronasal organ.
1979-01-01

Previous workers had identified the vomeronasal organ, on anatomical evidence, as an accessory olfactory organ, present in most terrestrial vertebrates. Lesion experiments had demonstrated its importance in sexual behaviour in the hamster. Howevever, the sequestered position of the vomeronasal receptor epithelium within the organ raised questions ...

PubMed Central

84
Sexually dimorphic activation of the accessory, but not the main, olfactory bulb in mice by urinary volatiles
2007-07-10

Previous research suggests that volatile body odourants detected by the main olfactory epithelium (MOE) are processed mainly by the main olfactory bulb (MOB) whereas nonvolatile body odourants detected by the vomeronasal organ (VNO) are processed via the accessory olfactory ...

PubMed Central

85
OMP-ZsGreen fluorescent protein transgenic mice for visualisation of olfactory sensory neurons in vivo and in vitro.
2011-01-12

Research into the biology of the mammalian olfactory system would be greatly enhanced by transgenic reporter mice with cell-specific fluorescence. To this end we previously generated a mouse whose olfactory ensheathing cells (OECs) express DsRed driven by the S100� promoter. We present here a transgenic reporter mouse whose olfactory ...

PubMed

86
Cladistic analysis of olfactory and vomeronasal systems.
2011-01-26

Most tetrapods possess two nasal organs for detecting chemicals in their environment, which are the sensory detectors of the olfactory and vomeronasal systems. The seventies' view that the olfactory system was only devoted to sense volatiles, whereas the vomeronasal system was exclusively specialized for pheromone detection was challenged by accumulating ...

PubMed

87
Cladistic Analysis of Olfactory and Vomeronasal Systems
2011-01-26

Most tetrapods possess two nasal organs for detecting chemicals in their environment, which are the sensory detectors of the olfactory and vomeronasal systems. The seventies� view that the olfactory system was only devoted to sense volatiles, whereas the vomeronasal system was exclusively specialized for pheromone detection was challenged by accumulating ...

PubMed Central

88
Changes in Maternal Gene Expression in Olfactory Circuits in the Immediate Postpartum Period
2011-07-01

Regulation of maternal behavior in the immediate postpartum period involves neural circuits in reward and homeostasis systems responding to cues from the newborn. Our aim was to assess one specific regulatory mechanism: the role that olfaction plays in the onset and modulation of parenting behavior. We focused on changes in gene expression in olfactory brain regions, examining ...

PubMed Central

89
The construction of olfactory representations Thomas A. Cleland

as well as locally situated memory effects. This process begins in the olfactory bulb. #12;19 The OB1 The construction of olfactory representations Thomas A. Cleland Dept. of Psychology Cornell in the resulting primary sensory representations. In the vertebrate olfactory system, much of the relevant neural

E-print Network

90
Olfactory Discriminating Ability of Lacustrine Sockeye and Masu Salmon in Various Freshwaters

... the olfactory discriminating ability of lacustrine sockeye salmon (Oncorhynchus nerka) and masu salmon (O. masou), the integrated olfactory ... olfactory bulb unit response in juvenile sockeye salmon (Onc...

NBII National Biological Information Infrastructure

91
Binaral interaction and centrifugal input enhances spatial contrast in olfactory bulb activation.
2007-01-01

We used paired-pulse odorant stimulation, with a conditioning stimulus delivered either ipsilateral or contralateral to a test stimulus, to unmask the effects of centrifugal feedback on olfactory bulb responses. In reptiles and mammals there are no direct connections between the paired olfactory bulbs, and thus all ...

PubMed

92
Spatial patterns of gene expression in the olfactory bulb
2004-08-24

How olfactory sensory neurons converge on spatially invariant glomeruli in the olfactory bulb is largely unknown. In one model, olfactory sensory neurons interact with spatially restricted guidance cues in the bulb that orient and guide them to their target. Identifying differentially expressed ...

PubMed Central

93
Localization and changes in distribution of brain alpha 2- and beta-adrenoceptors in response to acclimation state in the American bullfrog (Rana catesbeiana).
1998-05-01

Alpha (alpha)- and beta (beta)-adrenoceptors regulate physiological processes in vertebrates. This study determined the location of alpha 2- and beta-adrenoceptors in the brain of the American bullfrog, Rana catesbeiana, using autoradiography. As the density of receptors may be affected by environmental temperature, a comparative numerical analysis of adrenoceptors in the areas of localization ...

PubMed

94
Olfactory bulb habituation to odor stimuli
2010-08-01

Habituation is a simple form of memory, yet its neurobiological mechanisms are only beginning to be understood in mammals. In the olfactory system, the neural correlates of habituation at a fast experimental timescale involving very short intertrial intervals (tens of seconds) have been shown to depend on synaptic adaptation in olfactory cortex. In ...

PubMed Central

95
The NASA SCIence Files": Kids: Research Rack ... - NASA SCI Files

olfactory bulb a pea-sized structure on the undersurface of the frontal lobe of the brain that receives inputs from the olfactory neurons and sends the ...

NASA Website

96
8 - NASA Technical Reports Server

Mar 1, 2011 ... terminalis in the olfactory bulb of Clarias batrachus can be traced centripetally through the medial olfactory tract, telencephalon, ...

NASA Website

97
Grafting the Olfactory Epithelium to the Olfactory Bulb

BackgroundImpaired olfactory function leads to a decrease in the quality of life for many patients. Surgical treatment options are limited, especially for those suffering from hyposmia or anosmia following post-traumatic injury to the olfactory nerves. Stem cells located in the olfactory epithelium have the capacity to grow new ...

PubMed Central

98
Uptake of 203Hg2+ in the olfactory system in pike.
1996-02-01

Inorganic mercury (203Hg2+) was applied to the olfactory chambers or was given i.v. to pike (Esox lucius) and the uptake of the metal in the olfactory system and the brain was examined by autoradiography and gamma spectrometry. Application of 203Hg2+ in the olfactory chambers resulted in an accumulation of the metal in the ...

PubMed

99
Mammalian social odours: attraction and individual recognition
2006-11-08

Mammalian social systems rely on signals passed between individuals conveying information including sex, reproductive status, individual identity, ownership, competitive ability and health status. Many of these signals take the form of complex mixtures of molecules sensed by chemosensory systems and have important influences on a variety of behaviours that are vital for reproductive success, such ...

PubMed Central

100
The Role of Inhibition in an Associative Memory Model of the

The Role of Inhibition in an Associative Memory Model of the Olfactory Bulb Ofer Hendin and David (inhibitory) cells of the olfactory bulb (OB) take place. Two outstanding features of these interactions accreditted with the role of forming Hebbian cell assemblies. Hence it would seem that this structure lacks

E-print Network

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101
The Effect of X-Rays on the Activity of Neurons in the Rat Olfactory Bulb.
1965-01-01

Extracellular microelectrode recordings were made from single neurons of the olfactory bulb in anesthetized rats. Approximately 15 percent of the units examined responded in some way (usually an increase in frequency) to 250 kvp x-irradiation at dose rate...

National Technical Information Service (NTIS)

102
Response Patterns of Amphibian Olfactory Bulb Neurones to Odour Stimulation.
1974-01-01

Responses of 199 single olfactory bulb neurones were observed with odor stimulation. Some odor applications did not cause any change in the spontaneous activity of the unit, some applications caused an excitation during the rising concentration phase of t...

National Technical Information Service (NTIS)

103
Development of a Mathematical Description of the Olfactory Bulb, Validated with Intracellular and Voltage-Sensitive Dye Recordings.
1991-01-01

The objective of this work is to develop a detailed mathematical description of the function of the olfactory epithelium and bulb in the tiger salamander, an animal from which we, and others, have obtained substantial morphological, biochemical, physiolog...

National Technical Information Service (NTIS)

104
Olfactory bulb recovery following reversible deafferentation with repeated detergent application in the adult zebrafish.
2011-09-10

The neuroplasticity and regenerative properties of the olfactory system make it a useful model for studying the ability of the nervous system to recover from damage. We have developed a novel method for examining the effects of long-term deafferentation and regeneration of the olfactory organ and resulting influence on the olfactory ...

PubMed

105
Newborn neurons in the adult olfactory bulb: Unique properties for specific odor behavior.
2011-08-01

The generation of new cells in the adult brain reveals a new form of plasticity in the neuronal network. New cells are constantly migrating to and integrating into the pre-existing neuronal network in the olfactory bulb. The exact role of new neurons in the adult olfactory bulb and in odor behavior remains elusive ...

PubMed

106
The brain of the common vampire bat, Desmodus rotundus murinus (Wagner, 1840): a cytoarchitectural atlas.
2008-08-01

The vampire bat, Desmodus rotundus, is exceptionally agile and stealthy in nature. Feeding at night on cattle blood, it is a known scourge carrying rabies. It is endowed with a very high neocortical volume among bats, acute olfactory capabilities and an accessory olfactory system. These characteristics have resulted into an impressive ...

PubMed

107
QUANTIFYING ERRORS ASSOCIATED WITH USING PREY SKELETAL STRUCTURES FROM

to the olfactory bulb of the brain, a small ovoid structure that rests on the cribriform plate of the ethmoid bone

E-print Network

108
Neurogenesis in Humans
2009-04-14

Professor Fred Gage explains that neurogenesis only occurs in the hippocampus and the olfactory bulb in humans, and discusses why this might be so.

NSDL National Science Digital Library

109
An Analog Clustering Network from a Biological Model
1993-04-01

... these ("mitral") cells project via a of olfactory processing proposed by ... To implement feedback inhibition of the bulb by the piriform, we propose a ...

DTIC Science & Technology

110
7641 - NASA Technical Reports Server

Mar 1, 2011 ... Histochemical studies on the distribution of some enzymes of the glycolytic pathways in the olfactory bulb of the Squirrel Monkey ...

NASA Website

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