... Title : Accessory Sexual Glands of Male 'Blattella ... of development of the reproductive organs. Descriptors : (*INSECTS, *SEX GLANDS), MALES ...
DTIC Science & Technology
... for anatomic, morphologic, and histologic examination of the accessory sex organs. The 2nd group consisted of castrated animals. Six ... determine the effect of absence of testosterone on accessory sex or...
NBII National Biological Information Infrastructure
... of spleen, thymus and accessory sex glands. ... were not consistent for both sexes (kidney weights ... lesions observed in reproductive organs of mature ...
... and decline with progressive organ maturation, whereas ... for the formation of arborized organs that span ... processes in male accessory sex glands. ...
... estradiol-treatment has also been found in different accessory sex organs of the rabbit [20] and rat [11]. Many ... the weights and histology of the epididymis and sex accessory organs of sexually immatur...
... mechanisms similar to those of the limb and accessory sex organs to pattern penile postnatal morphogenesis and differentiation and ... the embryonic precursor of both the penis and accessory sex organs. T...
... and passive movement in the sexual passages of ... it a secretion of the accessory sex glands of ... waxy substance, originat- ing from the Zhene organ. ...
... Sexes, numbers, stage of mosquitoes at the time of collection ... percent infection of selected tissues and organs following an ... Accessory Gland ...
... family members of different sexes who are not ... of the proper central state organs" Mrs. Piasecka ... own equipment, tools, and accessories, raw and ...
for identifying pheromone molecules. Key words: vomeronasal organ; accessory olfactory bulb; pheromones; sex in the Accessory Olfactory Bulb Correlate with Sex-Specific Behaviors Arvind Kumar, Carol A. Dudley, and Robert L or accessory olfactory system plays a crucial role ...
E-print Network
... Pituitary gland and gonads from both sexes; uterus and ... as well as in other organs, were graded ... of the prostate and other accessory sex glands is ...
... by asynchronous function of the testes (spermatogenesis) and accessory sex organs. Structural factors in both sexes and fructose levels ... oviduct, vagina), and male reproductive tract (testes and access...
... adult rat after inanition with or without the dietary accessories, ... The effect of age, sex, and body size on the ... a series of 49 cats of both sexes it vwas ...
... among IBC-treated animals of both sexes. ... The following organs/tissues were examined ... kidneys, urinary bladder, accessory sex glands (male only ...
of the accessory sex structures during embryogenesis as described by Alfred Jost a few years previously, Young this Developmental Organization followed by Adult Activation paradigm, one tends to view sex differences in brain that are caused by the 'organizing effect of perinatal androgen' and ...
... in kits with accessories for anchoring ... Organ perforation � Bleeding (including hemorrhage/hematoma) ... pain, infection, dyspareunia (painful sex for patient ...
Center for Biologics Evaluation and Research (CBER)
... stomach, thyroid, thymus, trachea, urinary bladder, accessory sex organs, testes, epididymus ... Statistical analyses for organ weights were done on ...
organs by Drew (1969), there have been no ultra- structural studies of the male reproductive accessory Biology of Invertebrates, vol. III. Wiley, Chichester, pp. 319�471 (Accessory Sex Glands). Gillott, CUltrastructure of male reproductive accessory glands and ejaculatory duct in the ...
al. (2002), testes and accessory glands were dissected in phosphate-buffered saline (PBS). The organs of "sex" with "treatment" and "line in treatment"). Measures of testes and accessory gland size were gland size in the sex ratio selection lines. The figure shows mean ...
Organ/ system Early embryonic Mid embryonic Late embryonic Puberty Sexual maturity Gonad Accessory sex the expression of behaviors utilizing those organs. In vertebrates of both sexes, the gonadal steroids structures Accessory sex structures Brain Brain ...
in the functionality of gonads and accessory organs and in the development of the secondary sex traits. These results- strated that parental males exhibit less developed testes, more developed reproductive accessory organs- giante et al., '99). The male reproductive appara- tus contains ...
... RATS TO HALON 2402.a Sex Control 2.5 Percent 5 Percent 7.5 Percent 10 Percent ... Adrenals Skeletal muscle V Accessory genital organs. ...
... immunological testing evaluating function of accessory cells, T ... to one or more of the following organs ... study groups (including age, sex, race, years ...
... build and package the device and accessories in the ... measurements, animal information (weight, sex, breed), device ... Artif Organs 1994; 18:806-12. ...
... Reproduction 135: 713- 721. ... Influence of Dietary Soy Isoflavones on the Accessory Sex Organs of the Wistar Rat. Food Chem.Toxicol. ...
EPA Pesticide Factsheets
... for VDR heterodimerization are nuclear accessory factor (NAF ... target organs that included intestine, kidney, and ... toxicity study in both sexes of rats ...
sex hormones with receptors of the target organs has found itself ... conditions with tissue of the accessory sexual apparatus of male ...
NASA Website
and accessory organs than do males (e.g., Boyle et al. 1995) and presumably therefore invest more energy for the present analysis comprised: capture date, dorsal man- tle length (DML, mm), sex, gonad and accessory on the right-hand edge of the distribution (Fig. 6d). 3.2.2 Reproductive organ ...
of behaviors utilizing those organs. In vertebrates of both sexes, the gonadal steroids that regulate/ system Early embryonic Mid embryonic Late embryonic Puberty Sexual maturity Gonad Accessory sex structures Accessory sex structures Brain Brain Gonad Male Female ...
male or female insofar as they had a history of birth defect of the sex organs." He then continued role and orientation than is the chromosomal sex, the gonadal sex, the hormonal sex, the accessory of Gender and the Decline of Sex: Social Change in ...
with the differential development of the accessory sex structures during embryogenesis as described by Alfred Jost a few that are caused by the `organizing effect of perinatal androgen' and that can be related to sex differences Male circuit Female circuit Accessory olfactory bulb Vomeronasal ...
and through membership of mixed-sex aggregations. Male reproductive quality was estimated using accessory reproductive organs (Fig. 2b; partial correlation coefficients, accessory glands r = 0.39; testes r = 0 above), we found that males in mixed sex aggregations had significantly larger ...
the analogy with the differential development of the accessory sex structures during embryogenesis this Developmental Organization fol- lowed by Adult Activation paradigm, one tends to view sex differences in brain Female circuit Accessory olfactory bulb Vomeronasal organ ...
]. #12;the accessory glands, or paragonia, of the male internal genitalia, tissues that are present in only one sex,49�51]. That the sex hierarchy might also modulate theA/P organizer's function in the genital disc was suggested primordia is the sex of the cells in the A/P ...
- lular organisms. Amazingly enough, sci- entists cannot conclusively say why sex exists. In recent years. In this scenario, the female is the neutral, or default, sex, whereas the male is the organized sex. A key element could in�uence the developing neural and secondary and ...
on the gonadal differentiation in cold-blooded vertebrates, but on accessory and second sex structures in warm are not genetic model organisms, work on their sex determination is limited to candidate genes suggested from Crews and Bull, 1 Mode and Tempo in Environmental Sex Determination in ...
cycles and behavior (including species, sex, and age differences)? ..... accessory immune cells such as monocytes and macrophages, T and B cells themselves, ..... Other than sweat glands and brown adipose tissue, no specific organs ...
otolith organs by rotary and linear accelerations may either help or hinder .... The effects of a simple accessory stimulus on a single response to a ..... and 1000 matched controls, the same age, the same sex, and with the same kind of ...
Immature male albino rats, 30 days of age, were treated with 0.3 mg nicotine/100 g body weight either orally or intraperitoneally for 30 days. All the animals were autopsied on the 61 st day, by which time they were sexually mature. Testis, epididymis, seminal vesicle, prostate gland and vas deferens were dissected out, weighed, and processed for biochemical and histological studies. Weight of ...
PubMed
Testosterone is essential for quantitatively normal sperm production in the testis, normal sperm maturation in the epididymis, maintenance of the accessory sex organs, and effective sexual behavior. A variety of xenobiotics can result in a significant dec...
National Technical Information Service (NTIS)
Testosterone is essential for quantitatively normal sperm production in the testis, normal sperm maturation in the epididymis, maintenance of the accessory sex organs, and effective sexual behavior. ariety of xenobiotics can result in a significant decrease in spermatogenesis, sp...
EPA Science Inventory
Olive, corn, sesame or peanut oil which have been used as vehicles in the immature rat uterotrophic assay or Hershberger assay, for detection of endocrine disrupting effects of environmental chemicals, was administered to ten immature female rats by subcutaneous injection from postnatal day (PND) 21 for 3 or 7 days, and each oil was also administered to ten male rats from PND 21 for 7 and 10 days. ...
... seasonal cyclicity of the testes and accessory sex glands are described and illustrated. Accessory sex glands undergo an annual cycle in synchrony with the ... ...
It is known that abnormal androgen dynamics in the tissues is a cause of androgen-dependent disorders. Investigation of tissue androgen levels could provide a clue to the elucidation of disorders. However, it is difficult to measure a trace amount of androgen in the tissues. We established a highly sensitive simultaneous quantification method of testosterone and dihydrotestosterone (DHT), which ...
Pregnant Sprague-Dawley dams were exposed to a low-level, low-frequency pulsed electromagnetic (EM) field (15 Hz, 0.3 msec duration, peak intensity 8 gauss) for 15 min twice a day from day 15 through day 20 of gestation, a period in development that is critical for sexual differentiation of the male rat brain. No differences in litter size, number of stillborns, or body weight were observed in ...
Energy Citations Database
and receives input from the vomeronasal organ [28]. Accessory olfactory inputs to the amygdala are found, and physiological bases of social attachment. After mating, both sexes display pair bonds that extend beyond, pups were kept in same-sex sibling pairs until used in experiments. All animals were housed (plastic
. Y. (2004) Sexual dimorphism of the vomeronasal organ and the accessory olfactory bulbJournal of Neurocytology 34, 135�147 (2005) The vomeronasal organ of greater bushbabies (Otolemur spp.): Species, sex, and age differences TIMOTHY D. SMITH1,2, , KUNWAR P. BHATNAGAR3 , ANNE M. BURROWS
...fixation medium for both the type of tissue and the intended...epididymides, accessory sex organs (e.g., prostate...carried out on the preserved organs and tissues of all animals...performed on tissues and organs identified as showing...showing lesions, the type of lesions and the...
Code of Federal Regulations, 2011
, are solitary and territorial, and display sex differences in their EOD as adults. B The electric organ-cells sitting among accessory cells (ac) be- low the inner chamber (i.c.) of the mormyro- mast organ organ discharges that are used in orientation and com- munication. The peripheral and ...
Experiments were designed to determine whether x irradiation affects subsequent production of androgen, whether subsequent response of testis to gonadotropin is impaired, and whether accessory sex organs are affected. Male rats were exposed to 400, 800, or 1200 r at varying ages after birth (3 to 36 days). The subsequent ...
... The anatoiq of the organs of ciroulation, whioh are bore desoribed ... The organ. . ... the inferior medial or accessory (Sohaffner) lobe does not lie in a ...
The hypothesis tested in this study was that the membrane vesicles present in ram seminal plasma are of testicular origin, rather than being secreted by the accessory sex glands as has been previously reported for a number of species. Membrane vesicles were present in cellular extracts from reproductive organs and ...
The relationship between reproductive organs, circulating testosterone, and androstenedione concentration in the male sheath-tailed bat, Taphozous longimanus, was studied. The masses of testis, accessory sex gland (prostate, ampullary), and epididymides showed three peaks, one each in October, January, and April. Monthly changes in ...
in the accessory olfactory bulb (AOB) of mice as they sniff another mouse, the re- searchers have discovered neurons that vary their activity in response to the sex and ge- netic strain of the sniffee. This suggests are detected by re- ceptors in a small, cigar-shaped cavity at the back of the nose, the vomeronasal organ (VNO
) transferred at mating affect the reproductive success of both sexes. Such reproductive proteins often evolve proteomic method that uses whole-organism isotopic labeling to detect transferred Sfps in mated female D on three areas: (a) the effects of the full set of Sfps (and especially of accessory gland proteins
Moose Research Center, Alaska Department of Fish and Game, Soldotna, Alaska, USA2 Accessory antlers).The deciduous antlers are paired organs, which grow from permanent bony protuberances of frontal bone of connective tissue) (HARTWIGand SCHRUDDE,1974) by male sex hormones during puberty (BUBENIK,G., 1990; LI
... the evaluation of the enzyme content within sexed ... column under each sex provides more significant ... and common oviducts with accessory glands ...
Phoenix et al. (Phoenix et al., 1959) were the first to propose an essential role of fetal testosterone exposure in the sexual differentiation of the capacity of mammals to display male-typical mating behavior. In one experiment control male and female guinea pigs as well as females given fetal testosterone actually showed equivalent levels of mounting behavior when gonadectomized and given ...
PubMed Central
This study focuses on the consequences of the switch of tactic from parasitic to parental male in the black goby, Gobius niger (Teleostei: Gobiidae), a species showing two alternative male mating tactics. Older and larger males defend nests, court, and perform parental care on eggs, while younger and smaller ones behave as parasites, sneaking into nests while spawning occurs. Males adopting ...
The seasonal chronology of the events of the reproductive cycle, and changes in the structure and function of the primary and accessory organs of the male bent-winged bat, Miniopterus schreibersii, were studied at latitude 37 degrees S in temperate southeastern Australia. The testicular cycle commenced in late spring (November), and sperm appeared in the ...
A partially purified flavonoid-rich extract was prepared from the seed of Vitex negundo. The effect of this extract on the reproductive system of male rats was investigated at four different concentrations. All the major accessory sex organs shed weight when the preparation was administered at doses of >or=15 mg/rat/day after 15 ...
The volumetric changes of the corpora allata (CA) during the first 15 days of imaginal life of Blatta orientalis L. (Dictyoptera, Blattidae) are studied in connection with the growth of the accessory reproductive glands (GSAM). Both, the CA and the GSAM, grow in parallel during the first 3-4 days of imaginal life, which suggests a possible functional link between both ...
In the paper an attempt to define pathogenesis of changes in somatic growth of juvenile individuals of the popular freshwater snail Lymnaea stagnalis experimentally infected with parthenites of the trematode Opisthioglyphe ranae was undertaken. Significant enlargement of relative wet weight of examined accessory sex organs (albumen ...
The effect of chronic oral exposure to arsenic on male mouse testicular and accessory sex organ weights, sperm parameters and testicular marker enzymes was studied. In addition, the distribution of arsenic in reproductive organs was measured using atomic absorption spectrophotometry. Sodium arsenite administered to ...
Triclocarban (TCC; 3,4,4'-trichlorocarbanilide) is an antimicrobial agent used widely in various personal hygiene products including soaps. Recently, TCC has been shown to enhance testosterone-induced effects in vitro and to enlarge accessory sex organs in castrated male rats. This study was designed to evaluate the effects of TCC on ...
Triclocarban (TCC; 3,4,4?-trichlorocarbanilide) is an antimicrobial agent used widely in various personal hygiene products including soaps. Recently, TCC has been shown to enhance testosterone-induced effects in vitro and to enlarge accessory sex organs in castrated male rats. This study was designed to evaluate the effects of TCC on ...
Streptozotocin (STZ) is a naturally occurring compound isolated from Streptomyces achromogens. It is used extensively for inducing diabetes in experimental animals. Diabetes mellitus is known to have proven adverse effects on male sexual organs and their reproductive functions. The atrophy of prostate gland and other organs of the genitourinary tract were ...
We previously found that female mice exhibited Fos responses in the accessory olfactory bulb (AOB) after exposure to volatile opposite-sex, but not same-sex, urinary odours. This effect was eliminated by lesioning the main olfactory epithelium, raising the possibility that the AOB receives information about gender via centrifugal ...
The current study was designed to examine the modulating effects of bisphenol A (BPA) on prostate cancer risk in male offspring exposed transplacentally and lactationally. BPA was administered to F344 female rats by gavage at 0, 0.05, 7.5, 30, 120 mg/kg/day during pregnancy and lactation periods. When F1 males reached 5 weeks old, they were given 10 subcutaneous injections of ...
In order to determine whether the secretion of androgen by the ovary of the adult rat increases after x irradiation, irradiated ovaries were implanted into castrated male litter-mates, and pieces of prostate into both x-irradiated and normal female rats. The grafts of irradiated ovaries failed to vascularize and grow, and did not appear to secrete androgen, as judged by the weight of the ...
Boric acid (H3BO3), an inorganic acid with widespread commercial use and consumer exposure, impairs fertility in male rodents at dose levels lower than those required to cause other adverse effects. Previous studies found a testicular lesion in adult Fischer rats fed 9000 ppm boric acid (1575 ppm boron) and slightly reduced basal serum testosterone levels. A CNS-mediated hormonal component to this ...
Roe deer are seasonal breeders with a short rutting season from mid-July to mid-August. The seasonality of reproductive activity in males is associated with cyclic changes between growth and involution of both testes and the accessory sex glands. This study characterizes morphological and functional parameters of these organs prior to, ...
The extragonadal source of the high levels of 5 alpha-reduced androgens in the peripheral blood of the male rabbit has been investigated. Adult 3-day castrated rabbits each received a single intravenous injection of 3H-labelled testosterone, and blood plasma was collected at various intervals thereafter. Two h post injection, animals were killed, various accessory ...
Rapid industrialization has increased the burden of chemicals in the environment. These chemicals may be harmful to development and reproduction of any organism. We therefore analyzed the adverse effects of leachates from a tannery solid waste on development and reproduction using Drosophila. We show a significant delay in mean emergence of flies observed at the higher ...
We previously found that female mice exhibited Fos responses in the accessory olfactory bulb (AOB) after exposure to volatile opposite-, but not same-sex, urinary odours. This effect was eliminated by lesioning the main olfactory epithelium, raising the possibility that the AOB receives information about gender via centrifugal inputs originating in the ...
... The hypothesis that sex- Wehner, 1986; McIntyre et ... immune functions INFLUENCE OF SEXUAL BEHAVIOR (Hochman ... func- tion of accessory cells ...
... doublesex gene controls somatic sexual differentiation by ... 1993) The protein Sex-lethal antagonizes ... interactions with additional accessory factors. ...
... Gesteland, R. F. and J. F. Atkins. The RNA World. Cold Spring Harbor Laboratory Press. Cold Spring Harbor, ... ...
Professor Nelson explains that the prostate is actually a male sex accessory gland that contributes about a third of the secretions to the ejaculate for sexual reproduction.
NSDL National Science Digital Library
The rodent Hershberger assay is being validated as an in vivo test method for detecting androgenic or antiandrogenic compounds by the Organization for Economic Cooperation and Development (OECD). As part of the international validation work, we studied 17alpha-methyltestosterone for evaluating androgenic activity, and procymidone and p,p'-DDE for evaluating antiandrogenic ...
Arginase activity has been identified in the prostate, and may be important in the synthesis of polyamines in accessory sex glands in the male. Polyamines in turn may mediate the action of androgens. Diabetic patients have disordered androgen synthesis. The purpose of this work was to evaluate the effect of L-arginine on arginase activity in ...
... article and test article groups (both sexes) had mild ... live and dead foetuses, sex ratio, resorptions and pre ... 1506/16) had a reduced accessory lung lobe that was ...
... organ, accessory piece, squamodisc, anchors, hooks, bars, and clamps under laser scanning confocal microscopy. The copulatory and ... organ, accessory piece, squamodiscs, anchors, hooks, bars, and clamps...
... were also present in the accessory organs, the prostate, and seminal vesicles and its fluid. Using hyaluronic ... but was absent from the efferent ducts, the prostate, and the seminal vesicles/fluid. This...
Prostate cancer, the most prevalent non-cutaneous cancer in men, is associated with increased age. This suggests that dietary chemopreventive measures could be effective in delaying the onset or decreasing the severity of the disease. We utilized the Lobund-Wistar rat nitrosomethylurea induced, testosterone promoted (NMU-T) model of male sex accessory ...
Previous research suggests that volatile body odourants detected by the main olfactory epithelium (MOE) are processed mainly by the main olfactory bulb (MOB) whereas nonvolatile body odourants detected by the vomeronasal organ (VNO) are processed via the accessory olfactory bulb (AOB). We asked whether urinary volatiles from males and females ...
Rapid ejaculation is probably the most common form of male sexual dysfunction. Current research into the treatment of the condition has focused on centrally acting or topical desensitizing agents; however, no treatment has yet been approved. An alternative approach could be to develop drugs that act directly upon the target organ itself and our increasing knowledge of the ...
Androgen action on sex accessory organs influences rodent fertility, but the mechanisms remain unclear and investigation is difficult without the ability to restrict androgen action in specific tissues. We used Cre-LoxP technology to generate male mice with prostate epithelial-specific androgen receptor deficiency (denoted PEARKO). In ...
In male rats, experimentally induced diabetes mellitus has been reported to be associated with reduced serum levels of gonadotropins and testosterone as well as decreased sex accessory organ weights. The purpose of the present study was to determine if the decreased accessory organ weights and ...
BackgroundInternal reproductive organ size is an important determinant of male reproductive success. While the response of testis length to variation in the intensity of sperm competition is well documented across many taxa, few studies address the importance of testis size in determining other components of male reproductive success (such as mating frequency) or the ...
Non-volatile chemosignals in rodents are detected by unique receptors in the vomeronasal organ of the accessory olfactory system. Although the vomeronasal organ has been implicated in the regulation of sexually dimorphic behavioral and neuroendocrine functions, the underlying cellular mechanisms are undetermined. In previous studies we ...
Induction and branching morphogenesis of the prostate are dependent on androgens, which act via the mesenchyme to induce prostatic epithelial development. One mechanism by which the mesenchyme may regulate the epithelium is through secreted growth factors such as FGF-10. We have examined the male reproductive tract of FGF-10(-/-) mice, and at birth, most of the male secondary ...
Following chronic (15 or 30 days) treatment with oestradiol 3-benzoate (75 microg rat(-1) day(-1) in 100 microl of olive oil) to adult rats, androgen receptor (AR) expression was analysed simultaneously in testis, epididymis, seminal vesicle, prostate and pituitary utilising three independent tools i.e. immunohistochemistry, Western blotting and RT-PCR. All the five organs ...
In internally fertilizing organisms, mating involves a series of highly coordinated molecular interactions between the sexes that occur within the female reproductive tract. In species where females mate multiply, traits involved in postcopulatory interactions are expected to evolve rapidly, potentially leading to postmating-prezygotic (PMPZ) reproductive ...
Ceratotoxins are antibacterial peptides produced in the female reproductive accessory glands of the medfly Ceratitis capitata. Their expression is not affected by bacterial infection, but is enhanced after mating and is modulated by juvenile hormone. Three different peptides, named ceratotoxins A, B and C, have been previously purified from the female ...
Brain-derived neurotrophic factor (BDNF) is a growth factor belonging to the family of neurotrophins. Although neurotrophins in the male genital organs have been well documented, their role in the biology of these organs is far from clear. In particular, little is known about the influence of sex hormones on neurotrophin expression. In ...
The OECD has proposed a new, validated test guideline with the stimulated weanling male Hershberger assay to avoid the surgical castration step. In the present study, we assessed the relevance and reliability of the stimulated weanling Hershberger assay in four stages. All chemicals except for testosterone propionate (TP) were orally administered to sexually immature male rats of 22 days old for ...
The distribution and function of an Aplysia cardioexcitatory peptide, NdWFamide, were examined in the nervous system of pulmonate snails. We chemically identified the authentic NdWFamide from a land snail (Euhadra congenita) and a freshwater snail (Lymnaea stagnalis). NdWFamide potentiated the heartbeat of those snails. Immunohistochemistry using anti-NdWFamide antibody demonstrated the ...
We established an inbred rat strain with unilateral urogenital anomalies from an incidentally identified male rat with unilateral renal agenesis and an undescended left testis. These rats were characterized by unilateral renal agenesis in both sexes, undescended testes with agenesis and hypoplasia of the accessory sex ...
As a participating laboratory for the OECD Hershberger validation program, we conducted a phase 3 trial to test the reliability of the Hershberger assay using coded substances. Male Sprague-Dawley rats were castrated at 6 weeks of age and allowed to recover for 8 days. All the coded substances were administered orally once daily for 10 consecutive days. In the antagonist version of the assay, 0.4 ...
Hedgehog (Hh) proteins are expressed during vertebrate development in some tissues with inductive properties and at epithelial-mesenchymal boundaries in several developing organs, including the lung, gut, hair follicle, and tooth. The Hh signaling pathway is highly conserved, and important clues to understanding the mechanism of Hh signal transduction in vertebrates have come ...
For many organisms, pheromonal communication is of particular importance in managing various aspects of reproduction. In tetrapods, the vomeronasal (Jacobson's) organ specializes in detecting pheromones in biological substrates of congeners. This information triggers behavioral changes associated, in the case of certain pheromones, with neuroendocrine ...
The Organization for Economic Co-operation and Development (OECD) has initiated the development of new guidelines for the screening and testing of potential endocrine disrupters. The Hershberger assay is one of the assays selected for validation based on the need for in vivo screening to detect androgen agonists or antagonists by measuring the response of five ...
We evaluated the effects of three rodent diets differing in soybean meal content on the response of the seminal vesicles, prostate and bulbocavernosus/levator ani (BC/LA) muscle to androgens and anti-androgenic compounds in the Hershberger assay. The diets tested were (1) L5, a semi-synthetic phytoestrogen-free diet, (2) DO4, 8.5% (w/w) vegetable protein and (3) DO3, 22.5% (w/w) vegetable protein. ...
To determine if Butea superba Roxb., a traditional Thai male potency herb, has androgenic activity in 60-day-old male Wistar rats, we measured its effects on the pituitary-testicular axis and sex organs. Intact and orchidectomized adult male rats were subdivided into five groups (10 rats/group): distilled water, Butea superba (BS)-10, BS-50, BS-250, and ...