... 41 4.0 ACCORD Lipid..... 49 ... 53 ACCORD Lipid ..... 4.3 ACCORD Lipid Overall Results ..... 56 ...

The lipids are localized in the granulations of the leukocytes of the myeloid line in different ways according to whether neutrophiles and basophiles or eosinophiles are concerned. In the first case they are found throughout the granule, in the second at its periphery. In both cases an essential constituent of these lipids is ...

The mammalian liver, a key organ in lipid homeostasis, can accumulate increased amounts of lipids in certain physiological conditions including liver regeneration. Lipid droplets (LD), the lipid storage organelles in the cytoplasm, are composed of a core of neutral lipids (mainly ...

To examine lipid management in a large national outpatient network, a cross-sectional study was conducted that included 1,385,242 active patients ages 20 to 79 years of age in a national network of over 5000 providers using electronic health records (EHRs). Adequate lipid testing, achievement of lipid goals, and ...

Caveolins form plasmalemnal invaginated caveolae. They also locate around intracellular lipid droplets but their role in this location remains unclear. By studying primary adipocytes that highly express caveolin-1, we characterized the impact of caveolin-1 deficiency on lipid droplet proteome and lipidome. We identified several missing ...

Data are given of a comparative study of the growth and development as well as the characteristics of the biomass of the C. Lipolytica yeast according to the content of raw protein, protein, lipids, vitamins in the B group, and residual hydrocarbons durin...

Plant sterol esters reduce serum total cholesterol (TC) and LDL cholesterol (LDL-C), but with striking inter-individual variability. In this randomized, double-blind, controlled study, serum lipid, plant sterol, fat-soluble vitamin, and carotenoid responses to plant sterols were studied according to...

... Presented at the American College of Cardiology conference on March 14, 2010, the ACCORD Lipid Trial, funded by the National Institutes of Health (NIH ...

Abstract The Action to Control Cardiovascular Risks in Diabetes Study (ACCORD) was a well-designed trial of 10,251 patients with type 2 diabetes mellitus that studied the effects of tight control of blood sugar, hypertension, and lipids. Disappointingly, as compared with standard treatment, the use of intensive ...

Electric characteristics of hybrid polymer membranes composed of two lipid species were studied, where one lipid species is positively charged in aqueous solution and the other is negatively charged. As a result, it was found that the hybrid membranes responded to taste substances in different ways according to the ...

Classification of blood hyperlipemias by electrophoresis or ultracentrifugation according to density

... Measurement of Baseline albuminuria was not collected in the ACCORD-Lipid patients. Change to: Measurement of Baseline ...

Employing Monte Carlo dynamics, the equilibrium and dynamic properties of lipid-water systems are studied in the context of a diamond lattice realization. The model faithfully describe the lipid molecule geometry and reproduces the essential physical properties of real membranes. These include the phase transitions from ...

The structure of membrane lipids in Archaea is different from those of Bacteria and Eucarya in many ways including the chirality of the glycerol backbone. Until now, heterochiral membranes were believed to be unstable; thus, no cellular organism could have existed before the separation of the groups of life. In this study, we tested the formation of ...

Nutritional supports are required for liver transplant patients. However, no systematical assessment has been made of the optimal composition of energy yielding substrates in these patients. This study is to evaluate whether mixed energy system consisting of carbohydrate and lipid emulsions is more advantageous over single energy source of glucose for ...

The aim of this study was to examine whether malondialdehyde (MDA) formation, a marker of oxidant stress, is altered in different stages of development of hyperlipidemia and whether it correlates with atherogenic index (AI), an important risk factor of atherosclerosis. Commercial kits were used to measure the levels of lipid profile and antioxidant status ...

This is a report on a stored lipid atypical ultrastructural pattern in skin samples of Fabry's disease expressed exclusively in the endothelium. The pattern consisted of intersecting short crescentic tightly packed membranes with a periodicity identical to that in classical ultrastructural variants. At low magnification the lysosomal aggregates of the material resembled ...

Gemini surfactants possess interesting interfacial and aggregation properties that have prompted comprehensive studies and successful applications in a wide variety of fields. However, a systematic study on the effect of gemini tail and spacer length upon the organization of lipid membranes has not been presented so far. In this ...

... and Youngsburg (5), using the colorimetric of blood lipids and lipoproteins in the individ- ... study was designed to evaluate serum lipid and ...

THE PURPOSE OF THE REVIEW: Was analyzed basic data on the contribution of blood serum lipids in the development of gallstone disease (GSD) in the world as well as in northern Russia, as well as the association of cholelithiasis and coronary heart disease (CHD). RECENT LITERATURE DATA: Worldwide, there is suffer from cholelithiasis 10 to 15% of the population. In Russia, about ...

... On May 19, 2011, the committee will discuss the findings of the Action to Control Cardiovascular Risk in Diabetes-Lipid (ACCORD Lipid) trial as they relate to ...

What is a lipid? According to the Wikipedia on-line encyclopedia, lipids are " fatty acid esters, a class of water-insoluble organic molecules". ...

... This will be one predominant factor in atherosclerosis. Descriptors : (*Lipids, *Capillaries(Anatomy)), (*Lipoproteins, Capillaries ...

... and oxidative intermediates of lipids in dehydrated systems. It was reasoned that an understanding of protein reactions with lipid derived peroxides ...

predicted the diabetes complication of retinopathy very well. In the DETECT-2 project pooling 47,000 people from 13 studies, moderate non-proliferative diabetic retinopathy (as assessed by retinal photography pressure, and lipid control on progression of diabetic retinopathy in a sub-study of the ACCORD trial (NEJM

Olive mill wastewater was treated by an aerobic bio-process at different values of pH (with or without addition of lime), for 45 days on a laboratory scale, to evaluate the reduction of the organic load. The lipid content showed an appreciable change in relation to the applied treatment both for total lipids and for the different fractions (neutral ...

Viruses acquire their envelope by budding from a host cell membrane, but viral lipid composition may differ from that of the budding membrane. We have previously reported that the HIV-1 membrane is highly enriched in cholesterol, sphingolipids, and other raft lipids, suggesting that the virus may bud from pre-existing or virus-induced ...

ECA is a cell surface antigen found in all bacteria belonging to the family Enterobacteriaceae. The serological specificity of ECA is determined by a linear heteropolysaccharide comprised of trisaccharide repeat units; the component sugars are N-acetyl-D-glucosamine (GlcNAc), N-acetyl-D-mannosaminuronic acid (ManNAcUA), and 4-acetamido-D-fucose (Fuc4NAc). In vivo studies have ...

Our research on lipidic vectors for transfection led us to develop thiourea lipids able to interact with DNA. Hence, we developed a series of lipopolythioureas based on the strong hydrogen bond donor ability of thiourea. More recently we have reported a branched hydroxylated bis-thiourea derivative with interesting transfecting properties. The last step of ...

This paper compares the regeneration of nuclear and chromatin lipids from the liver and thymus of control and irradiated rats according to the criterion of the incorporation of (/sup 14/C) acetate. The chromatin-bound lipids were found to have high metabolic activity, which was sharply pronounced in thymus cells. The corresponding ...

This study has explored the use of lipid-based formulations to enhance the oral bioavailability of the poorly water-soluble drug anethol trithione (ATT), and compared the performance of different formulations. Two groups of lipid-based formulations, sub-microemulsion (SME) and oil solution, were prepared using short (SCT), medium (MCT) ...

Synthetic cationic lipids are presently the most widely used non-viral gene carriers. Examined here is a particularly attractive cationic lipid class, triester phosphatidylcholines (PCs) exhibiting low toxicities and good transfection efficiency. Similarly to other cationic lipids, they form stable complexes (lipoplexes) with the ...

This publication summarizes the studies directed towards the development of modern chromatographic methods in lipid research and their applications to the investigations of roe lipids of common food fishes in Finland. The lipid class composition of the to...

A thin-layer chromatographic method utilizing ultracold temperatures has been developed to separate phosphoglycerides containing only long-chain saturated fatty acids from phosphoglycerides containing fatty acids with any degree of unsaturation. The method is direct, nondiluting, and nondestructive. Since the surface-active lipids found in lung surfactant contain only ...

The heteropolysaccharide chains of enterobacterial common antigen (ECA) are made up of linear trisaccharide repeat units with the structure----3)-alpha-D-Fuc4NAc-(1----4)- beta-D-ManNAcA-(1----4)-alpha-D-GlcNAc-(1----, where Fuc4NAc is 4-acetamido-4,6-dideoxy-D-galactose, ManNAcA is N-acetyl-D-mannosaminuronic acid, and GlcNAc is N-acetyl-D-glucosamine. The assembly of these chains involves ...

In miners anthracosilicosis is caused by chronic exposure to coal dust and is characterized by progressive development of the inflammatory process, the expressed disorders of lipid metabolism, and immunodeficiency. In the experiment we revealed the stages of anthracosilicosis development according to which adequate measures of prevention and correction of ...

The stratified water column of the Black Sea produces a vertical succession of redox zones, stimulating microbial activity at the interfaces. Our study of intact polar membrane lipids (IPLs) in suspended particulate matter and sediments highlights their potential as biomarkers for assessing the taxonomic composition of live microbial biomass. Intact polar ...