SMAC{sup 4} is the US Department of Energy`s (DOE) information system that collects, stores, and analyzes information on all unclassified shipments to and from DOE facilities. SMAC is operated for and under the direction of DOE`s Office of Environmental Management (EM) Transportation Management Division (TMD). Currently, ...
Energy Citations Database
In addition to providing rapid retrieval of large amounts of shipping and receiving data in response to inquiries and allowing remote access to the data from dial-up terminals, shipment mobility/accountability collection system (SMAC) is a central accounting system for DOE transportation activities. This ...
Dec 2, 2001 ... only monitored by the crew's collective sense of smell. .... detection list and sense them all at the 24-hour SMAC. ...
NASA Website
Second mitochondria-derived activator of caspase (Smac) is a mitochondrial protein released into the cytosol during apoptosis. Smac mimetics have recently been touted as a novel therapeutic to induce apoptosis in cancer cells. The ability of Smac mimetics to induce apoptosis in vitro has been shown to be dependent upon both XIAP ...
PubMed Central
One hallmark of cancer cells is their compromised ability to undergo apoptosis, or programmed cell death. Strategies targeting key apoptosis regulators with the goal of overcoming resistance to apoptosis have significant therapeutic potential for the development of new classes of anticancer drugs. Smac is a pro-apoptotic protein which, by binding to the inhibitor of apoptosis ...
In 1994 (August-September) and in 1995 (July-October) faeces of Dutch veal calves and adult cattle was examined for the presence of verocytotoxin-producing Escherichia coli O157 (O157 VTEC). The samples were collected at slaughterhouses. In 1994, O157 VTEC were isolated from three (0.9%) of 365 fecal samples of veal calves. Faeces of adult cattle was not ...
PubMed
To study the effect of endotoxin on liver apoptosis, L02 liver cells were cultured and passaged in vitro, and then stimulated by endotoxin at 10 mg/mL for 4, 8, 16 and 24 h respectively. Liver apoptosis was flow cytometrically and fluorescently detected. Immunohistochemistry was used to detect the delivery of smac and caspase9. The delivery of liver cell ...
The Automated Transportation Management System (ATMS) Software User Guide (SUG) constitutes the user procedures for the ATMS System. Information in this document will be used by the user to operate the automated system. It is intended to be used as a reference manual to guide and direct the user(s) through the ATMS software product and its environment. The objectives of ATMS are as follows: to ...
DOE Information Bridge
Children with attention deficit hyperactivity disorder (ADHD) are at a significant risk for experiencing failure in school. The School Supports Checklist (SSC) helps to identify potential classroom-based supports for children with ADHD in elementary school. The checklist can be used to support planning and overcoming barriers for increasing access to the general education curriculum for children ...
ERIC Educational Resources Information Center
The four residues at the amino-terminus of mature Smac/DIABLO are an IAP binding motif (IBM). Upon exit from mitochondria, mature Smac interacts with inhibitor of apoptosis proteins (IAPs), abrogating caspase inhibition. We used the ubiquitin fusion model to express mature Smac in the cytosol. Transiently expressed mature ...
PURPOSE: Second mitochondria-derived activator of caspase (Smac) regulates chemotherapy-induced apoptosis. Smac mimetics have been tested in clinical trials as chemosensitizers. We determined the role of Smac in modulating the chemosensitivity of esophageal squamous cell carcinoma (ESCC). EXPERIMENTAL DESIGN: Smac ...
The Subcommittee on Spacecraft Maximum Allowable Concentrations (SMAC) reviewed reports prepared by NASA scientists nd contractors recommending SMACs for approximately 35 spacecraft contaminants. The subcommittee sought to determine whether the SMAC repor...
National Technical Information Service (NTIS)
NASA requested that the Committee on Toxicology establish guidelines for developing spacecraft maximum allowable concentrations (SMACs) that could be used uniformly by scientists involved in preparing SMACs for airborne contaminants and review the SMACs f...
NASA requested that the Committee on Toxicology establish guidelines for developing spacecraft maximum allowable concentrations (SMACs) that could be used uniformly by scientists involved in preparing SMACs for airborne contaminants and review the SMACs for individual contaminants to ascertain whether they are consistent with the ...
A new software package called Higher Order Theory-Structural/Micro Analysis Code (HOT-SMAC) has been
NASA Technical Reports Server (NTRS)
... interacts with multiple lAPs and relieves their inhibitory effect on caspases- 3, -7 and -9. Recently, a small molecule Smac-mimic compound (Smac ...
DTIC Science & Technology
...2011-01-01 2011-01-01 false Accounting and collections. 948.200 Section...AGRICULTURE IRISH POTATOES GROWN IN COLORADO Accounting and Collections § 948.200 Accounting and collections. (a) Each...
Code of Federal Regulations, 2011
The botany of Captain Beechey's voyage; comprising an account of the plants collected by Messrs. Lay and Collie, ... ...
NBII National Biological Information Infrastructure
Feb 12, 2008 ... Permissible Exposure Limits - radiation, muscle mass and strength, bone loss. Example: SMACs. Requirements ...
The Severe Malaria in African Children (SMAC) network was established to conduct mortality-based trials. Although falciparum malaria kills more than one million children each year, single centers cannot enroll enough patients to detect reductions of 20-30% in mortality rates. Our aim was to quantify and describe severe malaria across a variety of epidemiological settings so ...
Second mitochondria-derived activator of caspase (Smac) is a mitochondrial protein that promotes apoptosis in many kinds of cancers. Here, for the first time, the effects of Smac RNAi on growth and drug resistance to cisplatin [cis-diamminedichloroplatinum(II)] of lung cancer cells are investigated. Knockdown of Smac expression in A549 ...
T cell membrane receptors and signaling molecules assemble at the immunological synapse (IS) in a supramolecular activation cluster (SMAC), organized into two differentiated subdomains: the central SMAC (cSMAC), with the TCR, Lck, and linker for activation of T cells (LAT), and the peripheral SMAC ...
Small molecules designed to mimic the binding of Smac protein to X-linked inhibitor of apoptosis protein (XIAP) are being pursued as a promising new class of anticancer drugs. Herein, we report the design, synthesis, and comprehensive structure-activity relationship studies of a series of conformationally constrained bicyclic Smac mimetics. Our studies led ...
Mars Pathfinder Accounting, Budget, Cost and Workforce Reports Collection, ... variance reports, monthly management and accounting status reports in a ...
Abstract: The botany of Captain Beechey's voyage; comprising an account of the plants collected by Messrs, Lay and Collie, and other officers of the ...
... Title : Analysis, Design, and Prototyping Of Accounting Software for Navy Signal Intelligence Collection Systems Return On Investment Reporting. ...
The 2006 National Footprint Accounts (NFA) portion of the Compendium of Environmental Sustainability Indicator Collections, version 1.1 is a data set that ... ...
This document is a progress report on the Seismic Safety Margins Research Program (SSMRP) covering the period April 1, 1980, through June 30, 1980. The report gives a general description of the program, together with financial summaries and individual project details. Each project is summarized to show accomplishments, schedules, milestones and completion dates, budget and expenditures, and any ...
This document is a progress report on the Seismic Safety Margins Research Program (SSMRP) covering the period October 1 through December 31, 1980. This report gives a general description of the program, together with financial summaries and individual project details. Each project is summarized to show accomplishments, schedules, milestones and completion dates, budget and expenditures, and any ...
This document is a progress report on the Seismic Safety Margins Research Program (SSMRP) covering the period July 1 through September 30, 1980. The report gives a general description of the program, together with financial summaries and individual project details. Each project is summarized to show accomplishments, schedules, milestones, and completion dates, budget and expenditures, and any ...
This document is a progress report on the Seismic Safety Margins Research Program (SSMRP) covering the period April 1 through June 30, 1980. The report gives a general description of the program, together with financial summaries and individual project details. Each project is summarized to show accomplishments, schedules, milestones and completion dates, budget and expenditures, and any concerns ...
This document is a progress report on the Seismic Safety Margins Research Program (SSMRP) covering the period January 1, 1981 through March 31, 1981. The report gives a general description of the program, together with financial summaries and individual project details. Each project is summarized to show accomplishments, schedules, milestones and completion dates, budget and expenditures, and any ...
The Spacecraft Maximum Allowable Concentrations (SMACs) are exposure limits for airborne chemicals used by NASA in spacecraft. The aim of these SMACs is to protect the spacecrew against adverse health effects and performance decrements that would interfer...
The objectives of this study was to examine the intracellular mechanisms by which Smac/DIABLO sensitizes TRAiL-resistant breast cancer cells to undergo apoptosis, and enhances the therapeutic potential of tamoxifen, doxorubicin and paclitaxel. Overexpress...
As part of its efforts to promote safe conditions aboard spacecraft, NASA requested the National Research Council (NRC) to develop guidelines establishing spacecraft maximum allowable concentrations (SMACs) for contaminants, and to review SMACs for variou...
As part of its efforts to promote safe conditions aboard spacecraft, NASA requested the National Research Council (NRC) to develop guidelines for establishing spacecraft maximum allowable concentrations (SMAC's) for contaminants, and to review SMAC's for ...
The basic objective was to assess the accuracy of the program, Simulation Model of Automobile Collisions (SMAC). This was done by staging three collisions and comparing the SMAC accident reconstructions to the empirical collision data. A second objective ...
Higher-Order Theory--Structural/MicroAnalysis Code (HOT-SMAC) Developed ... A team of researchers from Glenn, the University of Virginia, the Ohio Aerospace ...
... the release of Smac/DIABLO from mitochondria and apoptosis induced by hydrogen peroxide in cardiomyocytes and C2C12 ... xianzhongxiao@xysm.net Abstract Oxidative stress may cause apoptosis of cardiomyocy...
... BAM Media M194: Tellurite Cefixime - Sorbitol MacConkey Agar (TC-SMAC). August 2010. ... M194 Tellurite Cefixime � Sorbitol MacConkey Agar (TC-SMAC). ...
Center for Food Safety and Applied Nutrition (CFSAN)
T cell�APC conjugation as mediated by leukocyte function-associated antigen-1 (LFA-1)�intercellular adhesion molecule (ICAM)-1 binding is followed by formation of the supramolecular activation cluster (SMAC) at the immunological synapse. The intracellular processes that regulate SMAC formation and its influence on T cell function are important ...
The development of the Sonic Mapping and caliper (SMAC) Tools has been part of an ongoing effort by Hot Hole Instruments, Inc. of Los Alamos, New Mexico, to provide the geothermal, oil and gas drilling industries with improved and accurate tools for the i...
... Hydrophobic carbon atoms on the side chain of Alanine, Proline ring and Isoleucine in Smac peptide are shown in yellow. ...
Acetaldehyde � Ammonia � Carbon Monoxide � Formaldehyde � Freon 113 � Hydrogen � Methane � Methanol � Octamethyl-trisiloxane � Trimethylsilanol ...
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
E-print Network
... after treatment with SH-130 and radiation. ... through biochemical, immunological and genetic methods, which ... assay to investigate the effects of Smac ...
The Spacecraft Maximum Allowable Concentration (SMAC) is the maximum concentration of an analyte permissible aboard an inhabited spacecraft [16]. ...
ATSDR=Agency for Toxic Substances and Disease Registry. SMAC=Spacecraft maximum allowable concentration. NASA=National Aeronautics and Space ...
analysis by High Performance Liquid Chromatography. In some cases, the reporting limit for a compound is greater than the SMAC for that ...
Research article High Smac/DIABLO expression is associated with early local recurrence of cervical cancer
The financial status of the fuel oil industry is discussed. Accounts receivable and collections, bad debt losses, and credit and cutoff policies are described.
Compendium of Environmental Sustainability Indicator Collections: 2006 National Footprint Accounts. Oakland, CA: Global Footprint Network (GFN). ...
... Title : Collection of Short Papers on the ... This paper presents a historical account of the project, a general description of the study area and the ...
... Title : COLLECTED PAPERS PREPARED UNDER WORK UNIT INTERSQUAD: A STUDY OF THE FACTORS WHICH ACCOUNT FOR THE ...
X-linked inhibitor of apoptosis protein (XIAP) is a potent inhibitor of caspases 3, 7 and 9, and mitochondrial Smac (second mitochondria-derived activator of caspase) release during apoptosis inhibits the activity of XIAP. In this study we show that cytosolic XIAP also feeds back to mitochondria to impair Smac release. We constructed a fluorescent ...
After the basic theory for SMAC is presented below, two applications of the algorithm with real hardware will be presented. The first moderate-damping application is a system with approximately 50 modes in the bandwidth with up to 5 percent damping. The second application has at least 70 modes in the bandwidth, but damping is always below 3 percent. In addition to the improved ...
GMAC, a modified version of Sorbitol MacConkey medium (SMAC), was produced with a reduced quantity of selective agents and incorporated gentiobiose. GMAC supported a higher recovery rate of heat- or acid-injured Escherichia coli O157:H7 cells than SMAC with cefixime and tellurite (CT-SMAC), while differentiating E. coli O157:H7 from ...
A system and method for funding a collective account via aggregating usage of electronic tags is disclosed. The system and method promotes the use of electronic tags, and the funding of collective accounts that may be associated with charitable or other philanthropic causes. Further benefits may be realized by ...
US Patent & Trademark Office Database
Language: English ...
Language: French ...
