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1

AUREA: an open-source software system for accurate and user-friendly identification of relative expression molecular signatures  

PubMed Central

Background Public databases such as the NCBI Gene Expression Omnibus contain extensive and exponentially increasing amounts of high-throughput data that can be applied to molecular phenotype characterization. Collectively, these data can be analyzed for such purposes as disease diagnosis or phenotype classification. One family of algorithms that has proven useful for disease classification is based on relative expression analysis and includes the Top-Scoring Pair (TSP), k-Top-Scoring Pairs (k-TSP), Top-Scoring Triplet (TST) and Differential Rank Conservation (DIRAC) algorithms. These relative expression analysis algorithms hold significant advantages for identifying interpretable molecular signatures for disease classification, and have been implemented previously on a variety of computational platforms with varying degrees of usability. To increase the user-base and maximize the utility of these methods, we developed the program AUREA (Adaptive Unified Relative Expression Analyzer)—a cross-platform tool that has a consistent application programming interface (API), an easy-to-use graphical user interface (GUI), fast running times and automated parameter discovery. Results Herein, we describe AUREA, an efficient, cohesive, and user-friendly open-source software system that comprises a suite of methods for relative expression analysis. AUREA incorporates existing methods, while extending their capabilities and bringing uniformity to their interfaces. We demonstrate that combining these algorithms and adaptively tuning parameters on the training sets makes these algorithms more consistent in their performance and demonstrate the effectiveness of our adaptive parameter tuner by comparing accuracy across diverse datasets. Conclusions We have integrated several relative expression analysis algorithms and provided a unified interface for their implementation while making data acquisition, parameter fixing, data merging, and results analysis ‘point-and-click’ simple. The unified interface and the adaptive parameter tuning of AUREA provide an effective framework in which to investigate the massive amounts of publically available data by both ‘in silico’ and ‘bench’ scientists. AUREA can be found at http://price.systemsbiology.net/AUREA/.

2013-01-01

2

High-throughput Image Analysis of Tumor Spheroids: A User-friendly Software Application to Measure the Size of Spheroids Automatically and Accurately.  

PubMed

The increasing number of applications of three-dimensional (3D) tumor spheroids as an in vitro model for drug discovery requires their adaptation to large-scale screening formats in every step of a drug screen, including large-scale image analysis. Currently there is no ready-to-use and free image analysis software to meet this large-scale format. Most existing methods involve manually drawing the length and width of the imaged 3D spheroids, which is a tedious and time-consuming process. This study presents a high-throughput image analysis software application - SpheroidSizer, which measures the major and minor axial length of the imaged 3D tumor spheroids automatically and accurately; calculates the volume of each individual 3D tumor spheroid; then outputs the results in two different forms in spreadsheets for easy manipulations in the subsequent data analysis. The main advantage of this software is its powerful image analysis application that is adapted for large numbers of images. It provides high-throughput computation and quality-control workflow. The estimated time to process 1,000 images is about 15 min on a minimally configured laptop, or around 1 min on a multi-core performance workstation. The graphical user interface (GUI) is also designed for easy quality control, and users can manually override the computer results. The key method used in this software is adapted from the active contour algorithm, also known as Snakes, which is especially suitable for images with uneven illumination and noisy background that often plagues automated imaging processing in high-throughput screens. The complimentary "Manual Initialize" and "Hand Draw" tools provide the flexibility to SpheroidSizer in dealing with various types of spheroids and diverse quality images. This high-throughput image analysis software remarkably reduces labor and speeds up the analysis process. Implementing this software is beneficial for 3D tumor spheroids to become a routine in vitro model for drug screens in industry and academia. PMID:25046278

Chen, Wenjin; Wong, Chung; Vosburgh, Evan; Levine, Arnold J; Foran, David J; Xu, Eugenia Y

2014-01-01

3

FACOPT: a user friendly FACility layout OPTimization system  

Microsoft Academic Search

The facility layout problem is a well-researched one. However, few effective and user friendly approaches have been proposed. Since it is an NP hard problem, various optimization approaches for small problems and heuristic approaches for the larger problems have been proposed. For the most part the more effective algorithms are not user friendly. On the other hand, user-friendly methods have

Jaydeep Balakrishnan; Chun-Hung Cheng; Kam-fai Wong

2003-01-01

4

CARE 3 user-friendly interface user's guide  

NASA Technical Reports Server (NTRS)

CARE 3 predicts the unreliability of highly reliable reconfigurable fault-tolerant systems that include redundant computers or computer systems. CARE3MENU is a user-friendly interface used to create an input for the CARE 3 program. The CARE3MENU interface has been designed to minimize user input errors. Although a CARE3MENU session may be successfully completed and all parameters may be within specified limits or ranges, the CARE 3 program is not guaranteed to produce meaningful results if the user incorrectly interprets the CARE 3 stochastic model. The CARE3MENU User Guide provides complete information on how to create a CARE 3 model with the interface. The CARE3MENU interface runs under the VAX/VMS operating system.

Martensen, A. L.

1987-01-01

5

User-friendly program for multitask analysis  

NASA Astrophysics Data System (ADS)

Research on lifting activities has led to the design of several useful tools for evaluating tasks that involve lifting and material handling. The National Institute for Occupational Safety and Health (NIOSH) has developed a single task lifting equation. This formula has been frequently used as a guide in the field of ergonomics and material handling. While being much more complicated, the multi-task formula will provide a more realistic analysis for the evaluation of lifting and material handling jobs. A user friendly tool has been developed to assist professionals in the field of ergonomics in analyzing multitask types of material handling jobs. The program allows for up to 10 different tasks to be evaluated. The program requires a basic understanding of the NIOSH lifting guidelines and the six multipliers that are involved in the analysis of each single task. These multipliers are: Horizontal Distance Multiplier (HM), Vertical Distance Multiplier (VM), Vertical Displacement Multiplier (DM), Frequency of lifting Multiplier (FM), Coupling Multiplier (CM), and the Asymmetry Multiplier (AM). Once a given job is analyzed, a researched list of recommendations is provided to the user in an attempt to reduce the potential risk factors that are associated with each task.

Caporali, Sergio A.; Akladios, Magdy; Becker, Paul E.

2000-10-01

6

User-friendly software for Mössbauer spectrum analysis  

Microsoft Academic Search

A new user-friendly software for analysis of Mössbauer-spectra has been developed. The program makes use of the advantages provided by the current generation of fast personal computers. An Evolution Algorithm1,2 is used for global search of Mössbauer parameters in order to enhance the reliability of the obtained results. Fitting of Lorentzians, Pseudo-Voigt line profiles, and deriving hyperfine-field distributions including correlations

Z. Klencsįr; E. Kuzmann; A. Vértes

1996-01-01

7

TIGER: A user-friendly interactive grid generation system for complicated turbomachinery and axis-symmetric configurations  

NASA Technical Reports Server (NTRS)

The issue of time efficiency in grid generation is addressed by developing a user friendly graphical interface for interactive/automatic construction of structured grids around complex turbomachinery/axis-symmetric configurations. The accuracy of geometry modeling and its fidelity is accomplished by adapting the nonuniform rational b-spline (NURBS) representation. A customized interactive grid generation code, TIGER, has been developed to facilitate the grid generation process for complicated internal, external, and internal-external turbomachinery fields simulations. The FORMS Library is utilized to build user-friendly graphical interface. The algorithm allows a user to redistribute grid points interactively on curves/surfaces using NURBS formulation with accurate geometric definition. TIGER's features include multiblock, multiduct/shroud, multiblade row, uneven blade count, and patched/overlapping block interfaces. It has been applied to generate grids for various complicated turbomachinery geometries, as well as rocket and missile configurations.

Shih, Ming H.; Soni, Bharat K.

1993-01-01

8

Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes  

PubMed Central

Pseudomonas aeruginosa is a well-studied opportunistic pathogen that is particularly known for its intrinsic antimicrobial resistance, diverse metabolic capacity, and its ability to cause life threatening infections in cystic fibrosis patients. The Pseudomonas Genome Database (http://www.pseudomonas.com) was originally developed as a resource for peer-reviewed, continually updated annotation for the Pseudomonas aeruginosa PAO1 reference strain genome. In order to facilitate cross-strain and cross-species genome comparisons with other Pseudomonas species of importance, we have now expanded the database capabilities to include all Pseudomonas species, and have developed or incorporated methods to facilitate high quality comparative genomics. The database contains robust assessment of orthologs, a novel ortholog clustering method, and incorporates five views of the data at the sequence and annotation levels (Gbrowse, Mauve and custom views) to facilitate genome comparisons. A choice of simple and more flexible user-friendly Boolean search features allows researchers to search and compare annotations or sequences within or between genomes. Other features include more accurate protein subcellular localization predictions and a user-friendly, Boolean searchable log file of updates for the reference strain PAO1. This database aims to continue to provide a high quality, annotated genome resource for the research community and is available under an open source license.

Winsor, Geoffrey L.; Van Rossum, Thea; Lo, Raymond; Khaira, Bhavjinder; Whiteside, Matthew D.; Hancock, Robert E. W.; Brinkman, Fiona S. L.

2009-01-01

9

A user friendly system for ultrasound carotid intima-media thickness image interpretation  

NASA Astrophysics Data System (ADS)

Assessment of Carotid Intima-Media Thickness (CIMT) by B-mode ultrasound is a technically mature and reproducible technology. Given the high morbidity, mortality and the large societal burden associated with CV diseases, as a safe yet inexpensive tool, CIMT is increasingly utilized for cardiovascular (CV) risk stratification. However, CIMT requires a precise measure of the thickness of the intima and media layers of the carotid artery that can be tedious, time consuming, and demand specialized expertise and experience. To this end, we have developed a highly user-friendly system for semiautomatic CIMT image interpretation. Our contribution is the application of active contour models (snake models) with hard constraints, leading to an accurate, adaptive and user-friendly border detection algorithm. A comparison study with the CIMT measurement software in Siemens Syngo® Arterial Health Package shows that our system gives a small bias in mean (0.049 +/-0.051mm) and maximum (0.010 +/- 0.083 mm) CIMT measures and offers a higher reproducibility (average correlation coefficients were 0.948 and 0.844 in mean and maximum CIMT respectively (P <0.001)). This superior performance is attributed to our novel interface design for hard constraints in the snake models.

Zhu, Xiangjun; Kendall, Christopher B.; Hurst, R. Todd; Liang, Jianming

2011-03-01

10

User-friendly and certificate-free grid security infrastructure  

Microsoft Academic Search

Certificate-based public key infrastructures are currently widely used in computational grids to support security services.\\u000a From a user’s perspective, however, certificate acquisition is time-consuming and public\\/private key management is non-trivial.\\u000a In this paper, we propose a security infrastructure for grid applications, in which users are authenticated using passwords.\\u000a Our infrastructure allows a user to perform single sign-on based only on

Jason Crampton; Hoon Wei Lim; Kenneth G. Paterson; Geraint Price

2011-01-01

11

Creating the User-Friendly Library by Evaluating Patron Perception of Signage.  

ERIC Educational Resources Information Center

Librarians at Indiana University Northwest Library surveyed patrons on how to make the library's collection and services more accessible by improving signage. Examines the effectiveness of signage to instruct users, reduce difficulties and fears, ameliorate negative experiences, and contribute to a user-friendly environment. (AEF)

Bosman, Ellen; Rusinek, Carol

1997-01-01

12

Your friends have more friends than you do: identifying influential mobile users through random walks  

Microsoft Academic Search

In this paper, we study the problem of identifying influential users in mobile social networks. Traditional approaches find these users through centralized algorithms on either friendship or social-contact graphs of all users. However, the computational complexity of these algorithms is known to be very high, making them unsuitable for large-scale networks. We propose a lightweight and distributed protocol, iWander, to

Bo Han; Aravind Srinivasan

2012-01-01

13

User-friendly biometric camera for speeding iris recognition systems  

Microsoft Academic Search

Among biometric modalities existing nowadays for person identification, iris pattern recognition has reputed as one of the best performance systems. Unfortunately it has the lack of the user-friendliness that can be seen in hand geometry or face systems. To overcome these problems we propose a new kind of camera to capture iris image.

Michael G. Lorenz; Luis Mengibar-Pozo; Judith Liu-Jimenez; Belen Fernandez-Saavedra

2008-01-01

14

User-Friendly Interface Developed for a Web-Based Service for SpaceCAL Emulations  

NASA Technical Reports Server (NTRS)

A team at the NASA Glenn Research Center is developing a Space Communications Architecture Laboratory (SpaceCAL) for protocol development activities for coordinated satellite missions. SpaceCAL will provide a multiuser, distributed system to emulate space-based Internet architectures, backbone networks, formation clusters, and constellations. As part of a new effort in 2003, building blocks are being defined for an open distributed system to make the satellite emulation test bed accessible through an Internet connection. The first step in creating a Web-based service to control the emulation remotely is providing a user-friendly interface for encoding the data into a well-formed and complete Extensible Markup Language (XML) document. XML provides coding that allows data to be transferred between dissimilar systems. Scenario specifications include control parameters, network routes, interface bandwidths, delay, and bit error rate. Specifications for all satellite, instruments, and ground stations in a given scenario are also included in the XML document. For the SpaceCAL emulation, the XML document can be created using XForms, a Webbased forms language for data collection. Contrary to older forms technology, the interactive user interface makes the science prevalent, not the data representation. Required versus optional input fields, default values, automatic calculations, data validation, and reuse will help researchers quickly and accurately define missions. XForms can apply any XML schema defined for the test mission to validate data before forwarding it to the emulation facility. New instrument definitions, facilities, and mission types can be added to the existing schema. The first prototype user interface incorporates components for interactive input and form processing. Internet address, data rate, and the location of the facility are implemented with basic form controls with default values provided for convenience and efficiency using basic XForms operations. Because different emulation scenarios will vary widely in their component structure, more complex operations are used to add and delete facilities.

Liszka, Kathy J.; Holtz, Allen P.

2004-01-01

15

User-friendly software for SANS data reduction  

NASA Astrophysics Data System (ADS)

At the Geesthacht Neutron Facility (GeNF) we have developed new software for the reduction of two-dimensional small-angle neutron scattering (SANS) data. The main motivation for this work was to create software for users of our SANS facilities that is easy to use. Another motivation was to provide users with software they can also use at their home institute. Therefore, the software is implemented on a personal computer running Windows. The program reads raw data from an area detector in binary or text format and produces text files containing the scattering curve. The cross section can be averaged over the whole area of the detector or over sectors only. Scripts can be used for the processing of large numbers of files.

Biemann, P.; Haese-Seiller, M.; Staron, P.

2000-03-01

16

Evaluating Digital Libraries: A User-Friendly Guide  

NSDL National Science Digital Library

This guide provides practical advice on the use of evaluation techniques in assessing digital libraries. Users will be able to design, implement, and report better evaluations within the context of developing, operating, and/or using digital libraries. Topics include the five basic steps in conducting an evaluation, types of evaluations, planning, survey methods, interviews and focus groups, observations, experiments, and reporting evaluation results. Each chapter discusses the evaluation technique, provides a case study, and offers references and additional tools. The guide is written in an informal, easy-reading style intended to encourage users to make evaluation a routine aspect of their work with digital libraries. The guide is also intended to build confidence in the evaluation process. A downloadable, printable version is provided.

Reeves, Thomas

17

CARE3MENU- A CARE III USER FRIENDLY INTERFACE  

NASA Technical Reports Server (NTRS)

CARE3MENU generates an input file for the CARE III program. CARE III is used for reliability prediction of complex, redundant, fault-tolerant systems including digital computers, aircraft, nuclear and chemical control systems. The CARE III input file often becomes complicated and is not easily formatted with a text editor. CARE3MENU provides an easy, interactive method of creating an input file by automatically formatting a set of user-supplied inputs for the CARE III system. CARE3MENU provides detailed on-line help for most of its screen formats. The reliability model input process is divided into sections using menu-driven screen displays. Each stage, or set of identical modules comprising the model, must be identified and described in terms of number of modules, minimum number of modules for stage operation, and critical fault threshold. The fault handling and fault occurence models are detailed in several screens by parameters such as transition rates, propagation and detection densities, Weibull or exponential characteristics, and model accuracy. The system fault tree and critical pairs fault tree screens are used to define the governing logic and to identify modules affected by component failures. Additional CARE3MENU screens prompt the user for output options and run time control values such as mission time and truncation values. There are fourteen major screens, many with default values and HELP options. The documentation includes: 1) a users guide with several examples of CARE III models, the dialog required to input them to CARE3MENU, and the output files created; and 2) a maintenance manual for assistance in changing the HELP files and modifying any of the menu formats or contents. CARE3MENU is written in FORTRAN 77 for interactive execution and has been implemented on a DEC VAX series computer operating under VMS. This program was developed in 1985.

Pierce, J. L.

1994-01-01

18

A User-Friendly Software Package for HIFU Simulation  

NASA Astrophysics Data System (ADS)

A freely-distributed, MATLAB (The Mathworks, Inc., Natick, MA)-based software package for simulating axisymmetric high-intensity focused ultrasound (HIFU) beams and their heating effects is discussed. The package (HIFU_Simulator) consists of a propagation module which solves the Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation and a heating module which solves Pennes' bioheat transfer (BHT) equation. The pressure, intensity, heating rate, temperature, and thermal dose fields are computed, plotted, the output is released to the MATLAB workspace for further user analysis or postprocessing.

Soneson, Joshua E.

2009-04-01

19

Evaluating Websites for Older Adults: Adherence to "Senior-Friendly" Guidelines and End-User Performance  

ERIC Educational Resources Information Center

Older adults in the US are the fastest-growing demographic, and also the largest-growing group of internet users. The aim of this research was to evaluate websites designed for older adults in terms of (1) how well they adhere to "senior-friendly" guidelines and (2) overall ease of use and satisfaction. In Experiment I, 40 websites designed for…

Hart, T. A.; Chaparro, B. S.; Halcomb, C. G.

2008-01-01

20

Is Your Institution User-Friendly? Essential Elements of Successful Graduate Student Recruitment.  

ERIC Educational Resources Information Center

Two studies of variables influencing graduate students' consideration and choice of school found positive association with university personnel was a prime enrollment motivator. Students' decision process has changed over time. Evidence suggests students prefer an institution that is "user-friendly," affordable, and committed to quality. Cost and…

Olson, Carol

1992-01-01

21

Design and implementation of user friendly remote controllers for rescue robots in fire sites  

Microsoft Academic Search

Robot applications with rescue operations have been widely developed for disaster prevention purposes such as fire-fighting robot, rescue robot, and surveillance robot. This paper proposes two novel wireless remote controllers which offer not only user friendly operating interface but also easy robot controls. The handheld type controller is able to be easily carried by fire fighters and the joystick based

Young-Duk Kim; Jeon-Ho Kang; Duk-Han Sun; Jeon-Il Moon; Young-Sun Ryuh; Jinung An

2010-01-01

22

Design and implementation of user-friendly remote controllers for rescue robots used at fire sites  

Microsoft Academic Search

Many robotic applications have been developed for rescue operations during disasters; these applications involve the use of different types of robots such as fire-fighting robots, rescue robots, and surveillance robots. In this paper, we propose two novel wireless remote controllers that not only offer a user-friendly operating interface but also enable easy control of a robot. The handheld controller can

Young-Duk Kim; Jeong-Ho Kang; Duk-Han Sun; Jeon-Il Moon; Young-Sun Ryuh; Jinung An

2010-01-01

23

WAM (Wald's Approximation Method): a user-friendly software program for efficient covariate model building  

Microsoft Academic Search

A new software utility (WAM) based on the efficient covariate model building algorithm proposed by Kowalski and Hutmacher (2001) is presented and will be made available on the NONMEM repository (ftp:\\/\\/ftp.globomaxnm.com\\/Public\\/nonmem\\/). The WAM software is a user-friendly freeware utility that ranks all 2k possible covariate sub-models (presence or absence of k covariate parameters) based on Wald's approximation to Schwarz's Bayesian

K. G. Kowalski; W. Wang; D. Hermann

2004-01-01

24

A user friendly software tool for the simulation and optimization of high power fiber lasers  

Microsoft Academic Search

Double-clad rare-earth-doped fiber laser is a new generation of high power solid-state lasers. The numerical simulation is an important approach in the configuration design and parameter optimization for the high power fiber lasers (HPFLs). In this paper, we report our user-friendly high-power fiber laser simulation software system, which integrates the design, analysis and optimization functions together. The numerical simulations of

Liang Shang; Qinghe Mao

2008-01-01

25

Chipster: user-friendly analysis software for microarray and other high-throughput data  

PubMed Central

Background The growth of high-throughput technologies such as microarrays and next generation sequencing has been accompanied by active research in data analysis methodology, producing new analysis methods at a rapid pace. While most of the newly developed methods are freely available, their use requires substantial computational skills. In order to enable non-programming biologists to benefit from the method development in a timely manner, we have created the Chipster software. Results Chipster (http://chipster.csc.fi/) brings a powerful collection of data analysis methods within the reach of bioscientists via its intuitive graphical user interface. Users can analyze and integrate different data types such as gene expression, miRNA and aCGH. The analysis functionality is complemented with rich interactive visualizations, allowing users to select datapoints and create new gene lists based on these selections. Importantly, users can save the performed analysis steps as reusable, automatic workflows, which can also be shared with other users. Being a versatile and easily extendable platform, Chipster can be used for microarray, proteomics and sequencing data. In this article we describe its comprehensive collection of analysis and visualization tools for microarray data using three case studies. Conclusions Chipster is a user-friendly analysis software for high-throughput data. Its intuitive graphical user interface enables biologists to access a powerful collection of data analysis and integration tools, and to visualize data interactively. Users can collaborate by sharing analysis sessions and workflows. Chipster is open source, and the server installation package is freely available.

2011-01-01

26

IR, NLP, AI and UFOS: or IRrelevance, natural language problems, artful intelligence and user-friendly online systems  

Microsoft Academic Search

User Friendly Online Searching is examined in the context of Natural Language Processing in Information Retrieval and Artificial Intelligence. Opportunities for synergetic R & D are identified as the basis for Intelligent Information Retrieval and Artificial Retrieval Intelligence.

Tamas E. Doszkocs

1986-01-01

27

A Full-Featured User Friendly CO{sub 2}-EOR and Sequestration Planning Software  

SciTech Connect

A Full-Featured, User Friendly CO{sub 2}-EOR and Sequestration Planning Software This project addressed the development of an integrated software solution that includes a graphical user interface, numerical simulation, visualization tools and optimization processes for reservoir simulation modeling of CO{sub 2}-EOR. The objective was to assist the industry in the development of domestic energy resources by expanding the application of CO{sub 2}-EOR technologies, and ultimately to maximize the CO{sub 2} sequestration capacity of the U.S. The software resulted in a field-ready application for the industry to address the current CO{sub 2}-EOR technologies. The software has been made available to the public without restrictions and with user friendly operating documentation and tutorials. The software (executable only) can be downloaded from NITEC’s website at www.nitecllc.com. This integrated solution enables the design, optimization and operation of CO{sub 2}-EOR processes for small and mid-sized operators, who currently cannot afford the expensive, time intensive solutions that the major oil companies enjoy. Based on one estimate, small oil fields comprise 30% of the of total economic resource potential for the application of CO{sub 2}-EOR processes in the U.S. This corresponds to 21.7 billion barrels of incremental, technically recoverable oil using the current “best practices”, and 31.9 billion barrels using “next-generation” CO{sub 2}-EOR techniques. The project included a Case Study of a prospective CO{sub 2}-EOR candidate field in Wyoming by a small independent, Linc Energy Petroleum Wyoming, Inc. NITEC LLC has an established track record of developing innovative and user friendly software. The Principle Investigator is an experienced manager and engineer with expertise in software development, numerical techniques, and GUI applications. Unique, presently-proprietary NITEC technologies have been integrated into this application to further its ease of use and technical functionality.

Savage, Bill

2013-11-30

28

ROCOPT: A user friendly interactive code to optimize rocket structural components  

NASA Technical Reports Server (NTRS)

ROCOPT is a user-friendly, graphically-interfaced, microcomputer-based computer program (IBM compatible) that optimizes rocket components by minimizing the structural weight. The rocket components considered are ring stiffened truncated cones and cylinders. The applied loading is static, and can consist of any combination of internal or external pressure, axial force, bending moment, and torque. Stress margins are calculated by means of simple closed form strength of material type equations. Stability margins are determined by approximate, orthotropic-shell, closed-form equations. A modified form of Powell's method, in conjunction with a modified form of the external penalty method, is used to determine the minimum weight of the structure subject to stress and stability margin constraints, as well as user input constraints on the structural dimensions. The graphical interface guides the user through the required data prompts, explains program options and graphically displays results for easy interpretation.

Rule, William K.

1989-01-01

29

ITS Version 3.0: Powerful, user-friendly software for radiation modelling  

SciTech Connect

ITS (the Integrated Tiger Series) is a powerful, but user-friendly, software package permitting state-of-the-art modelling of electron and/or photon radiation effects. The programs provide Monte Carlo solution of linear time-independent coupled electron/photon radiation transport problems, with or without the presence of macroscopic electric and magnetic fields. The ITS system combines operational simplicity and physical accuracy in order to provide experimentalist and theorists alike with a method for the routine but rigorous solution of sophisticated radiation transport problems.

Kensek, R.P.; Halbleib, J.A.; Valdez, G.D.

1993-12-31

30

A user-friendly interface for surgeons to create haptic effects in medical simulation.  

PubMed

Haptics, namely the sense of touch, has been playing an important role in medical simulation. However, most medical practitioners, who are best suited to create the training environments, do not have the engineering expertise necessary for programming a haptic environment. We propose a user-friendly interface that allows surgeons to arbitrarily select regions on a 3D model of an organ, similar to "painting-by-numbers", and tune the haptic properties of each region in an intuitive way. The selected region and tuned haptic properties are recorded in a lookup table in real-time. The proposed user interface is assessed by comparing the haptic effects of a tumor on a virtual liver created by a number of surgeons. PMID:17377301

Ni, Liya; Wang, David W L; Dubrowski, Adam; Carnahan, Heather

2007-01-01

31

User-friendly tools for quantifying the dynamics of cellular morphology and intracellular protein clusters.  

PubMed

Understanding the heterogeneous dynamics of cellular processes requires not only tools to visualize molecular behavior but also versatile approaches to extract and analyze the information contained in live-cell movies of many cells. Automated identification and tracking of cellular features enable thorough and consistent comparative analyses in a high-throughput manner. Here, we present tools for two challenging problems in computational image analysis: (1) classification of motion for cells with complex shapes and dynamics and (2) segmentation of clustered cells and quantification of intracellular protein distributions based on a single fluorescence channel. We describe these methods and user-friendly software(1) (MATLAB applications with graphical user interfaces) so these tools can be readily applied without an extensive knowledge of computational techniques. PMID:24974040

Tsygankov, Denis; Chu, Pei-Hsuan; Chen, Hsin; Elston, Timothy C; Hahn, Klaus M

2014-01-01

32

Visual TSUNAMI: A Versatile, User-Friendly, Multidimensional Ablation and Gas-Dynamics Design Code  

SciTech Connect

Gas dynamics phenomena in thick-liquid protected inertial fusion target chambers have been explored since the early 1990's with the help of a series of simulation codes known as TSUNAMI. The code has been recently redesigned entirely to make use of modern programming techniques, languages and software; improve its user-friendliness; and refine its ability to model thick-liquid protected chambers, while expanding its capability to a larger variety of systems. The new code is named 'Visual Tsunami' to emphasize the programming language of its core, Fortran 95, as well as its graphics-based input file builder and output processors. It is aimed at providing a user-friendly design tool for complex systems for which transient gas dynamics phenomena play a key role.

Debonnel, C.S.; Wang, T.X.; Suzuki, M.; Garcia, E.; Peterson, P.F. [University of California (United States)

2005-05-15

33

A user-friendly computational workflow for the analysis of microRNA deep sequencing data.  

PubMed

Second-generation high-throughput sequencing is a robust and inexpensive methodology that is becoming an increasingly common technique for the study of microRNA (miRNA) expression levels in the central nervous system. This method allows for the identification of both known and novel miRNAs, reporting on the qualitative and quantitative levels these RNA species represent in any given sample. Numerous bioinformatic programs are currently available to analyze deep sequencing data but many require at least a partial understanding of the command line interface. In this chapter, we describe a user-friendly computational workflow guiding the user through the process from the initial FASTQ deep sequencing file to the identification of known and potentially novel miRNAs in a given experiment, as well as the assessment of the differential expression of these miRNAs between experimental samples. Furthermore, programs that can predict potential targets for these miRNAs are also highlighted. PMID:23007497

Majer, Anna; Caligiuri, Kyle A; Booth, Stephanie A

2013-01-01

34

SLIMS--a user-friendly sample operations and inventory management system for genotyping labs  

PubMed Central

Summary: We present the Sample-based Laboratory Information Management System (SLIMS), a powerful and user-friendly open source web application that provides all members of a laboratory with an interface to view, edit and create sample information. SLIMS aims to simplify common laboratory tasks with tools such as a user-friendly shopping cart for subjects, samples and containers that easily generates reports, shareable lists and plate designs for genotyping. Further key features include customizable data views, database change-logging and dynamically filled pre-formatted reports. Along with being feature-rich, SLIMS' power comes from being able to handle longitudinal data from multiple time-points and biological sources. This type of data is increasingly common from studies searching for susceptibility genes for common complex diseases that collect thousands of samples generating millions of genotypes and overwhelming amounts of data. LIMSs provide an efficient way to deal with this data while increasing accessibility and reducing laboratory errors; however, professional LIMS are often too costly to be practical. SLIMS gives labs a feasible alternative that is easily accessible, user-centrically designed and feature-rich. To facilitate system customization, and utilization for other groups, manuals have been written for users and developers. Availability: Documentation, source code and manuals are available at http://genapha.icapture.ubc.ca/SLIMS/index.jsp. SLIMS was developed using Java 1.6.0, JSPs, Hibernate 3.3.1.GA, DB2 and mySQL, Apache Tomcat 6.0.18, NetBeans IDE 6.5, Jasper Reports 3.5.1 and JasperSoft's iReport 3.5.1. Contact: denise.daley@hli.ubc.ca

Van Rossum, Thea; Tripp, Ben; Daley, Denise

2010-01-01

35

BATS: a Bayesian user-friendly software for Analyzing Time Series microarray experiments  

PubMed Central

Background Gene expression levels in a given cell can be influenced by different factors, namely pharmacological or medical treatments. The response to a given stimulus is usually different for different genes and may depend on time. One of the goals of modern molecular biology is the high-throughput identification of genes associated with a particular treatment or a biological process of interest. From methodological and computational point of view, analyzing high-dimensional time course microarray data requires very specific set of tools which are usually not included in standard software packages. Recently, the authors of this paper developed a fully Bayesian approach which allows one to identify differentially expressed genes in a 'one-sample' time-course microarray experiment, to rank them and to estimate their expression profiles. The method is based on explicit expressions for calculations and, hence, very computationally efficient. Results The software package BATS (Bayesian Analysis of Time Series) presented here implements the methodology described above. It allows an user to automatically identify and rank differentially expressed genes and to estimate their expression profiles when at least 5–6 time points are available. The package has a user-friendly interface. BATS successfully manages various technical difficulties which arise in time-course microarray experiments, such as a small number of observations, non-uniform sampling intervals and replicated or missing data. Conclusion BATS is a free user-friendly software for the analysis of both simulated and real microarray time course experiments. The software, the user manual and a brief illustrative example are freely available online at the BATS website:

Angelini, Claudia; Cutillo, Luisa; De Canditiis, Daniela; Mutarelli, Margherita; Pensky, Marianna

2008-01-01

36

A user-friendly web portal for T-Coffee on supercomputers  

PubMed Central

Background Parallel T-Coffee (PTC) was the first parallel implementation of the T-Coffee multiple sequence alignment tool. It is based on MPI and RMA mechanisms. Its purpose is to reduce the execution time of the large-scale sequence alignments. It can be run on distributed memory clusters allowing users to align data sets consisting of hundreds of proteins within a reasonable time. However, most of the potential users of this tool are not familiar with the use of grids or supercomputers. Results In this paper we show how PTC can be easily deployed and controlled on a super computer architecture using a web portal developed using Rapid. Rapid is a tool for efficiently generating standardized portlets for a wide range of applications and the approach described here is generic enough to be applied to other applications, or to deploy PTC on different HPC environments. Conclusions The PTC portal allows users to upload a large number of sequences to be aligned by the parallel version of TC that cannot be aligned by a single machine due to memory and execution time constraints. The web portal provides a user-friendly solution.

2011-01-01

37

RobiNA: a user-friendly, integrated software solution for RNA-Seq-based transcriptomics  

PubMed Central

Recent rapid advances in next generation RNA sequencing (RNA-Seq)-based provide researchers with unprecedentedly large data sets and open new perspectives in transcriptomics. Furthermore, RNA-Seq-based transcript profiling can be applied to non-model and newly discovered organisms because it does not require a predefined measuring platform (like e.g. microarrays). However, these novel technologies pose new challenges: the raw data need to be rigorously quality checked and filtered prior to analysis, and proper statistical methods have to be applied to extract biologically relevant information. Given the sheer volume of data, this is no trivial task and requires a combination of considerable technical resources along with bioinformatics expertise. To aid the individual researcher, we have developed RobiNA as an integrated solution that consolidates all steps of RNA-Seq-based differential gene-expression analysis in one user-friendly cross-platform application featuring a rich graphical user interface. RobiNA accepts raw FastQ files, SAM/BAM alignment files and counts tables as input. It supports quality checking, flexible filtering and statistical analysis of differential gene expression based on state-of-the art biostatistical methods developed in the R/Bioconductor projects. In-line help and a step-by-step manual guide users through the analysis. Installer packages for Mac OS X, Windows and Linux are available under the LGPL licence from http://mapman.gabipd.org/web/guest/robin.

Lohse, Marc; Bolger, Anthony M.; Nagel, Axel; Fernie, Alisdair R.; Lunn, John E.; Stitt, Mark; Usadel, Bjorn

2012-01-01

38

RobiNA: a user-friendly, integrated software solution for RNA-Seq-based transcriptomics.  

PubMed

Recent rapid advances in next generation RNA sequencing (RNA-Seq)-based provide researchers with unprecedentedly large data sets and open new perspectives in transcriptomics. Furthermore, RNA-Seq-based transcript profiling can be applied to non-model and newly discovered organisms because it does not require a predefined measuring platform (like e.g. microarrays). However, these novel technologies pose new challenges: the raw data need to be rigorously quality checked and filtered prior to analysis, and proper statistical methods have to be applied to extract biologically relevant information. Given the sheer volume of data, this is no trivial task and requires a combination of considerable technical resources along with bioinformatics expertise. To aid the individual researcher, we have developed RobiNA as an integrated solution that consolidates all steps of RNA-Seq-based differential gene-expression analysis in one user-friendly cross-platform application featuring a rich graphical user interface. RobiNA accepts raw FastQ files, SAM/BAM alignment files and counts tables as input. It supports quality checking, flexible filtering and statistical analysis of differential gene expression based on state-of-the art biostatistical methods developed in the R/Bioconductor projects. In-line help and a step-by-step manual guide users through the analysis. Installer packages for Mac OS X, Windows and Linux are available under the LGPL licence from http://mapman.gabipd.org/web/guest/robin. PMID:22684630

Lohse, Marc; Bolger, Anthony M; Nagel, Axel; Fernie, Alisdair R; Lunn, John E; Stitt, Mark; Usadel, Björn

2012-07-01

39

Ganga: User-friendly Grid job submission and management tool for LHC and beyond  

NASA Astrophysics Data System (ADS)

Ganga has been widely used for several years in ATLAS, LHCb and a handful of other communities. Ganga provides a simple yet powerful interface for submitting and managing jobs to a variety of computing backends. The tool helps users configuring applications and keeping track of their work. With the major release of version 5 in summer 2008, Ganga's main user-friendly features have been strengthened. Examples include a new configuration interface, enhanced support for job collections, bulk operations and easier access to subjobs. In addition to the traditional batch and Grid backends such as Condor, LSF, PBS, gLite/EDG a point-to-point job execution via ssh on remote machines is now supported. Ganga is used as an interactive job submission interface for end-users, and also as a job submission component for higher-level tools. For example GangaRobot is used to perform automated, end-to-end testing of distributed data analysis. Ganga comes with an extensive test suite covering more than 350 test cases. The development model involves all active developers in the release management shifts which is an important and novel approach for the distributed software collaborations. Ganga 5 is a mature, stable and widely-used tool with long-term support from the HEP community.

Vanderster, D. C.; Brochu, F.; Cowan, G.; Egede, U.; Elmsheuser, J.; Gaidoz, B.; Harrison, K.; Lee, H. C.; Liko, D.; Maier, A.; Mo?cicki, J. T.; Muraru, A.; Pajchel, K.; Reece, W.; Samset, B.; Slater, M.; Soroko, A.; Tan, C. L.; Williams, M.

2010-04-01

40

A user-friendly PC-based data acquisition and analysis system for respirometric investigations.  

PubMed

We have developed an easy-to-use computer-based system for recording, displaying, storing and analyzing signals generated by Clark-type oxygen electrodes. A user-friendly interface of Windows-based program BioMed significantly increases the productivity of investigations. It allows to process, control, present and archive the experimental data in real time. A 12-bit analog-to-digital-converter, analog and digital filters, a possibility to zoom the obtained respiratory curves and calculation of the respiration rates by a linear regression method increase the resolution of the estimated oxygen consumption rates. The new system enables to register even small changes, such as 3-5 ngatoms O/min, in respiration rates of biological objects -- enzymes, mitochondria and permeabilized muscle fibers. The system has been developed and is regularly used for the respirometric investigations at the Laboratory of Biochemistry, Institute for Biomedical Research, Kaunas University of Medicine. PMID:16678932

Kopustinskas, Audris; Adaskevicius, Rimas; Krusinskas, Andrius; Kopustinskiene, Dalia M; Liobikas, Julius; Toleikis, Adolfas

2006-06-01

41

USER friendly cloning coupled with chitin-based natural transformation enables rapid mutagenesis of Vibrio vulnificus.  

PubMed

Vibrio vulnificus is a bacterial contaminant of shellfish and causes highly lethal sepsis and destructive wound infections. A definitive identification of virulence factors using the molecular version of Koch's postulates has been hindered because of difficulties in performing molecular genetic analysis of this opportunistic pathogen. For example, conjugation is required to introduce plasmid DNA, and allelic exchange suicide vectors that rely on sucrose sensitivity for counterselection are not efficient. We therefore incorporated USER friendly cloning techniques into pCVD442-based allelic exchange suicide vectors and other expression vectors to enable the rapid and efficient capture of PCR amplicons. Upstream and downstream DNA sequences flanking genes targeted for deletion were cloned together in a single step. Based on results from Vibrio cholerae, we determined that V. vulnificus becomes naturally transformable with linear DNA during growth on chitin in the form of crab shells. By combining USER friendly cloning and chitin-based transformation, we rapidly and efficiently produced targeted deletions in V. vulnificus, bypassing the need for two-step, suicide vector-mediated allelic exchange. These methods were used to examine the roles of two flagellin loci (flaCDE and flaFBA), the motAB genes, and the cheY-3 gene in motility and to create deletions of rtxC, rtxA1, and fadR. Additionally, chitin-based transformation was useful in moving antibiotic resistance-labeled mutations between V. vulnificus strains by simply coculturing the strains on crab shells. The methods and genetic tools that we developed should be of general use to those performing molecular genetic analysis and manipulation of other gram-negative bacteria. PMID:19502446

Gulig, Paul A; Tucker, Matthew S; Thiaville, Patrick C; Joseph, Jennifer L; Brown, Roslyn N

2009-08-01

42

PuffinPlot: A versatile, user-friendly program for paleomagnetic analysis  

NASA Astrophysics Data System (ADS)

PuffinPlot is a user-friendly desktop application for analysis of paleomagnetic data, offering a unique combination of features. It runs on several operating systems, including Windows, Mac OS X, and Linux; supports both discrete and long core data; and facilitates analysis of very weakly magnetic samples. As well as interactive graphical operation, PuffinPlot offers batch analysis for large volumes of data, and a Python scripting interface for programmatic control of its features. Available data displays include demagnetization/intensity, Zijderveld, equal-area (for sample, site, and suite level demagnetization data, and for magnetic susceptibility anisotropy data), a demagnetization data table, and a natural remanent magnetization intensity histogram. Analysis types include principal component analysis, Fisherian statistics, and great-circle path intersections. The results of calculations can be exported as CSV (comma-separated value) files; graphs can be printed, and can also be saved as publication-quality vector files in SVG or PDF format. PuffinPlot is free, and the program, user manual, and fully documented source code may be downloaded from http://code.google.com/p/puffinplot/.

Lurcock, P. C.; Wilson, G. S.

2012-06-01

43

A user-friendly software to easily count Anopheles egg batches  

PubMed Central

Background Studies on malaria vector ecology and development/evaluation of vector control strategies often require measures of mosquito life history traits. Assessing the fecundity of malaria vectors can be carried out by counting eggs laid by Anopheles females. However, manually counting the eggs is time consuming, tedious, and error prone. Methods In this paper we present a newly developed software for high precision automatic egg counting. The software written in the Java programming language proposes a user-friendly interface and a complete online manual. It allows the inspection of results by the operator and includes proper tools for manual corrections. The user can in fact correct any details on the acquired results by a mouse click. Time saving is significant and errors due to loss of concentration are avoided. Results The software was tested over 16 randomly chosen images from 2 different experiments. The results show that the proposed automatic method produces results that are close to the ground truth. Conclusions The proposed approaches demonstrated a very high level of robustness. The adoption of the proposed software package will save many hours of labor to the bench scientist. The software needs no particular configuration and is freely available for download on: http://w3.ualg.pt/?hshah/eggcounter/.

2012-01-01

44

User Friendly Open GIS Tool for Large Scale Data Assimilation - a Case Study of Hydrological Modelling  

NASA Astrophysics Data System (ADS)

Open source software (OSS) coding has tremendous advantages over proprietary software. These are primarily fuelled by high level programming languages (JAVA, C++, Python etc...) and open source geospatial libraries (GDAL/OGR, GEOS, GeoTools etc.). Quantum GIS (QGIS) is a popular open source GIS package, which is licensed under GNU GPL and is written in C++. It allows users to perform specialised tasks by creating plugins in C++ and Python. This research article emphasises on exploiting this capability of QGIS to build and implement plugins across multiple platforms using the easy to learn - Python programming language. In the present study, a tool has been developed to assimilate large spatio-temporal datasets such as national level gridded rainfall, temperature, topographic (digital elevation model, slope, aspect), landuse/landcover and multi-layer soil data for input into hydrological models. At present this tool has been developed for Indian sub-continent. An attempt is also made to use popular scientific and numerical libraries to create custom applications for digital inclusion. In the hydrological modelling calibration and validation are important steps which are repetitively carried out for the same study region. As such the developed tool will be user friendly and used efficiently for these repetitive processes by reducing the time required for data management and handling. Moreover, it was found that the developed tool can easily assimilate large dataset in an organised manner.

Gupta, P. K.

2012-08-01

45

QualitySNPng: a user-friendly SNP detection and visualization tool  

PubMed Central

QualitySNPng is a new software tool for the detection and interactive visualization of single-nucleotide polymorphisms (SNPs). It uses a haplotype-based strategy to identify reliable SNPs; it is optimized for the analysis of current RNA-seq data; but it can also be used on genomic DNA sequences derived from next-generation sequencing experiments. QualitySNPng does not require a sequenced reference genome and delivers reliable SNPs for di- as well as polyploid species. The tool features a user-friendly interface, multiple filtering options to handle typical sequencing errors, support for SAM and ACE files and interactive visualization. QualitySNPng produces high-quality SNP information that can be used directly in genotyping by sequencing approaches for application in QTL and genome-wide association mapping as well as to populate SNP arrays. The software can be used as a stand-alone application with a graphical user interface or as part of a pipeline system like Galaxy. Versions for Windows, Mac OS X and Linux, as well as the source code, are available from http://www.bioinformatics.nl/QualitySNPng.

Nijveen, Harm; van Kaauwen, Martijn; Esselink, Danny G.; Hoegen, Brechtje; Vosman, Ben

2013-01-01

46

ClimatePipes: User-Friendly Data Access, Manipulation, Analysis & Visualization of Community Climate Models  

NASA Astrophysics Data System (ADS)

The impact of climate change will resonate through a broad range of fields including public health, infrastructure, water resources, and many others. Long-term coordinated planning, funding, and action are required for climate change adaptation and mitigation. Unfortunately, widespread use of climate data (simulated and observed) in non-climate science communities is impeded by factors such as large data size, lack of adequate metadata, poor documentation, and lack of sufficient computational and visualization resources. We present ClimatePipes to address many of these challenges by creating an open source platform that provides state-of-the-art, user-friendly data access, analysis, and visualization for climate and other relevant geospatial datasets, making the climate data available to non-researchers, decision-makers, and other stakeholders. The overarching goals of ClimatePipes are: - Enable users to explore real-world questions related to climate change. - Provide tools for data access, analysis, and visualization. - Facilitate collaboration by enabling users to share datasets, workflows, and visualization. ClimatePipes uses a web-based application platform for its widespread support on mainstream operating systems, ease-of-use, and inherent collaboration support. The front-end of ClimatePipes uses HTML5 (WebGL, Canvas2D, CSS3) to deliver state-of-the-art visualization and to provide a best-in-class user experience. The back-end of the ClimatePipes is built around Python using the Visualization Toolkit (VTK, http://vtk.org), Climate Data Analysis Tools (CDAT, http://uv-cdat.llnl.gov), and other climate and geospatial data processing tools such as GDAL and PROJ4. ClimatePipes web-interface to query and access data from remote sources (such as ESGF). Shown in the figure is climate data layer from ESGF on top of map data layer from OpenStreetMap. The ClimatePipes workflow editor provides flexibility and fine grained control, and uses the VisTrails (http://www.vistrails.org) workflow engine in the backend.

Chaudhary, A.; DeMarle, D.; Burnett, B.; Harris, C.; Silva, W.; Osmari, D.; Geveci, B.; Silva, C.; Doutriaux, C.; Williams, D. N.

2013-12-01

47

Fluorescent silver nanoclusters for user-friendly detection of Cu2+ on a paper platform.  

PubMed

The development of a user-friendly sensing platform for the detection of Cu(2+) in water is necessary as there are wide concerns due to the substantial impact of Cu(2+) on human health, environmental monitoring, and so on. Motivated by this, we report a fluorescent silver nanoclusters (AgNCs)-based sensor for the detection of Cu(2+). These water-soluble AgNCs, as a new class of fluorescent probes, were synthesized by using azobenzene modified poly(acrylic acid) (MPAA) as templates. Their fluorescence can be quenched in the presence of Cu(2+), which enables the label-free detection of Cu(2+) in real water samples. Furthermore, such AgNCs can be integrated onto cellulose filter paper and used as fluorescent indicators for Cu(2+). The fluorescence quenching can be observed by the naked eye under UV light. It should be noted that this AgNCs-based paper assay performs successfully in barrelled drinking water and river water samples. Therefore, it opens up new avenues to the development of robust clusters-based sensing platforms. PMID:22489282

Liu, Xiaojuan; Zong, Chenghua; Lu, Lehui

2012-05-21

48

A User-Friendly Model for Spray Drying to Aid Pharmaceutical Product Development  

PubMed Central

The aim of this study was to develop a user-friendly model for spray drying that can aid in the development of a pharmaceutical product, by shifting from a trial-and-error towards a quality-by-design approach. To achieve this, a spray dryer model was developed in commercial and open source spreadsheet software. The output of the model was first fitted to the experimental output of a Büchi B-290 spray dryer and subsequently validated. The predicted outlet temperatures of the spray dryer model matched the experimental values very well over the entire range of spray dryer settings that were tested. Finally, the model was applied to produce glassy sugars by spray drying, an often used excipient in formulations of biopharmaceuticals. For the production of glassy sugars, the model was extended to predict the relative humidity at the outlet, which is not measured in the spray dryer by default. This extended model was then successfully used to predict whether specific settings were suitable for producing glassy trehalose and inulin by spray drying. In conclusion, a spray dryer model was developed that is able to predict the output parameters of the spray drying process. The model can aid the development of spray dried pharmaceutical products by shifting from a trial-and-error towards a quality-by-design approach.

Grasmeijer, Niels; de Waard, Hans; Hinrichs, Wouter L. J.; Frijlink, Henderik W.

2013-01-01

49

A user-friendly model for spray drying to aid pharmaceutical product development.  

PubMed

The aim of this study was to develop a user-friendly model for spray drying that can aid in the development of a pharmaceutical product, by shifting from a trial-and-error towards a quality-by-design approach. To achieve this, a spray dryer model was developed in commercial and open source spreadsheet software. The output of the model was first fitted to the experimental output of a Büchi B-290 spray dryer and subsequently validated. The predicted outlet temperatures of the spray dryer model matched the experimental values very well over the entire range of spray dryer settings that were tested. Finally, the model was applied to produce glassy sugars by spray drying, an often used excipient in formulations of biopharmaceuticals. For the production of glassy sugars, the model was extended to predict the relative humidity at the outlet, which is not measured in the spray dryer by default. This extended model was then successfully used to predict whether specific settings were suitable for producing glassy trehalose and inulin by spray drying. In conclusion, a spray dryer model was developed that is able to predict the output parameters of the spray drying process. The model can aid the development of spray dried pharmaceutical products by shifting from a trial-and-error towards a quality-by-design approach. PMID:24040240

Grasmeijer, Niels; de Waard, Hans; Hinrichs, Wouter L J; Frijlink, Henderik W

2013-01-01

50

A user-friendly, highly sensitive assay to detect the IFN-? secretion by T cells  

PubMed Central

Objectives Development of a user-friendly test alternative to ELISA-based assays to detect IFN-? by in vitro cultured peripheral blood mononuclear cells (PBMC) stimulated with pathogen-derived antigens. Design and methods The molecular components of an operational IFN-? ELISA-based test were applied in a lateral flow (LF) immuno-sandwich assay using up-converting phosphor (UCP) reporter particles. The analytical sensitivity of the UCP-LF IFN-? assay (ULIGA) was determined and the assay was qualitatively validated with a selection of 60 supernatants derived from PBMC cultures stimulated with M. leprae derived antigens, mitogen or medium alone. Results ULIGA indicated an analytical sensitivity better than 2 pg/mL, and demonstrated four orders of magnitude dynamic range. The assay correlated well with the IFN-? ELISA. Conclusions ULIGA allows detection well below the cutoff value (100 pg/mL) used to define positive responses in the IFN-? ELISA. The test procedure is less demanding in respect to equipment and labor, and is suited for testing single samples.

Corstjens, Paul L.A.M.; Zuiderwijk, Michel; Tanke, Hans J.; van der Ploeg-Schip, Jolien; Ottenhoff, Tom H.M.; Geluk, Annemiek

2008-01-01

51

On-site earthquake early warning with multiple regression analysis: Featuring two user-friendly applications for Excel  

NASA Astrophysics Data System (ADS)

A variety of user-friendly spreadsheet templates have been developed for geoscience studies. However, the use of the built-in matrix functions within spreadsheet programs, such as Excel, is not particularly straightforward, lowering the value of spreadsheet programs for matrix-based computations, such as multiple regression analyses. Therefore, this study first developed two applications for Excel to perform multiple regression analyses in a much more user-friendly manner. Then using earthquake time histories from a reputable database, a series of regression analyses were performed. A new framework for on-site earthquake early warning based on multiple regression analyses is presented as an alternative to conventional models which were developed with single regression analyses.

Wang, J. P.; Huang, Duruo; Chang, Su-Chin; Brant, Logan

2013-08-01

52

Rapid, effective and user-friendly immunophenotyping of canine lymphoma using a personal flow cytometer  

PubMed Central

Background Widespread use of flow cytometry for immunophenotyping in clinical veterinary medicine is limited by cost and requirement for considerable laboratory space, staff time, and expertise. The Guava EasyCyte Plus (Guava Technologies, Hayward, CA, US) is the first, personal, bench-top flow cytometer designed to address these limitations. Objective The aim of this study was to adapt the immunohistochemical protocol used for immunophenotyping of canine lymphoma to the personal flow cytometer for rapid, effective and user-friendly application to the diagnosis and prognosis of canine lymphoma and to demonstrate its practicality for widespread veterinary application. Performance of the personal flow cytometer for immunophenotyping T and B lymphocytes in blood and lymph nodes from normal dogs and dogs with lymphoproliferative disease, was assessed using only two monoclonal antibodies (against CD3 and CD21), and by comparison with analysis using two conventional flow cytometers. Methods 26 dogs with lymphoproliferative disease (23 with lymphoma, 3 with lymphocytic leukaemia) were studied along with 15 controls (2 non-lymphoma lymph nodes and 13 non-leukemic bloods. Lymphocytes were immunostained with fluorescent-labeled, monoclonal antibodies against CD3 and CD21. To assess the effectiveness of the personal flow cytometer in discrimination between T and B cell immunophenotypes, T and B cell counts for half the samples (14 blood and 11 lymph node) were also determined using the same method and conventional flow cytometers (FACSCalibur, Cyan Dako). To assess the effectiveness of the personal flow cytometer in discriminating between leukocyte types, lymphocyte differential counts were determined for 21 blood samples and compared with those from automated hematology analyzers (CELL-DYN 3500, n=11 and ADVIA 2120, n=10). Quality and sub-cellular distribution of immunostaining was assessed using fluorescence microscopy. Results The protocol for immunophenotyping took 2 to 3 hours to complete from the point of receipt of sample to reporting of immunophenotype. The personal flow cytometer differential lymphocyte counts correlated highly (n=20; r=0.97, p<0.0001) with those of automated haematology analyzers. The personal flow cytometer counts consistently, but mildly, underestimated the percentages of lymphocytes in the samples (mean bias of -5.3%.). The personal flow cytometer immunophenotype counts were indistinguishable from those of conventional flow cytometers for both peripheral blood samples (n=13; r=0.95; p<0.0001; bias of -1.1%) and lymph node aspirates (n=11,r=0.98; p<0.001; bias of 1%). All but one leukemic and one lymphomatous lymph node sample, out of 26 samples of dogs with lymphoproliferative disease analyzed, could be immunophenotyped as either B or T cells. Conclusions We conclude that use of only 2 monoclonal antibodies is sufficient for immunophenotyping most cases of canine lymphoma by flow cytometry and enables rapid immunophenotyping. The personal flow cytometer may be as effectively used for immunophenotyping canine lymphoma as conventional flow cytometers. However, the personal flow cytometer is more accessible and user-friendly, and requires lower sample volumes.

2013-01-01

53

A graphical user-friendly interface for MCR-ALS: a new tool for multivariate curve resolution in MATLAB  

Microsoft Academic Search

A new graphical user-friendly interface for Multivariate Curve Resolution using Alternating Least Squares has been developed as a freely available MATLAB toolbox. Through the use of this new easy-to-use graphical interface, the selection of the type of data analysis (either individual experiments giving a single data matrix or the more powerful simultaneous analysis of several experiments using one or more

Joaquim Jaumot; Raimundo Gargallo; Anna de Juan; Romą Tauler

2005-01-01

54

Implementation and application of an interactive user-friendly validation software for RADIANCE  

NASA Astrophysics Data System (ADS)

RADIANCE extracts CT dose parameters from dose sheets using optical character recognition and stores the data in a relational database. To facilitate validation of RADIANCE's performance, a simple user interface was initially implemented and about 300 records were evaluated. Here, we extend this interface to achieve a wider variety of functions and perform a larger-scale validation. The validator uses some data from the RADIANCE database to prepopulate quality-testing fields, such as correspondence between calculated and reported total dose-length product. The interface also displays relevant parameters from the DICOM headers. A total of 5,098 dose sheets were used to test the performance accuracy of RADIANCE in dose data extraction. Several search criteria were implemented. All records were searchable by accession number, study date, or dose parameters beyond chosen thresholds. Validated records were searchable according to additional criteria from validation inputs. An error rate of 0.303% was demonstrated in the validation. Dose monitoring is increasingly important and RADIANCE provides an open-source solution with a high level of accuracy. The RADIANCE validator has been updated to enable users to test the integrity of their installation and verify that their dose monitoring is accurate and effective.

Sundaram, Anand; Boonn, William W.; Kim, Woojin; Cook, Tessa S.

2012-02-01

55

Accurate GPS Time-Linked data Acquisition System (ATLAS II) user's manual.  

SciTech Connect

The Accurate Time-Linked data Acquisition System (ATLAS II) is a small, lightweight, time-synchronized, robust data acquisition system that is capable of acquiring simultaneous long-term time-series data from both a wind turbine rotor and ground-based instrumentation. This document is a user's manual for the ATLAS II hardware and software. It describes the hardware and software components of ATLAS II, and explains how to install and execute the software.

Jones, Perry L.; Zayas, Jose R.; Ortiz-Moyet, Juan (PrimeCore Systems Inc., Albuquerque, NM)

2004-02-01

56

MASH Suite: A User-Friendly and Versatile Software Interface for High-Resolution Mass Spectrometry Data Interpretation and Visualization  

NASA Astrophysics Data System (ADS)

The rapid advancements in mass spectrometry (MS) instrumentation, particularly in Fourier transform (FT) MS, have made the acquisition of high-resolution and high-accuracy mass measurements routine. However, the software tools for the interpretation of high-resolution MS data are underdeveloped. Although several algorithms for the automatic processing of high-resolution MS data are available, there is still an urgent need for a user-friendly interface with functions that allow users to visualize and validate the computational output. Therefore, we have developed MASH Suite, a user-friendly and versatile software interface for processing high-resolution MS data. MASH Suite contains a wide range of features that allow users to easily navigate through data analysis, visualize complex high-resolution MS data, and manually validate automatically processed results. Furthermore, it provides easy, fast, and reliable interpretation of top-down, middle-down, and bottom-up MS data. MASH Suite is convenient, easily operated, and freely available. It can greatly facilitate the comprehensive interpretation and validation of high-resolution MS data with high accuracy and reliability.

Guner, Huseyin; Close, Patrick L.; Cai, Wenxuan; Zhang, Han; Peng, Ying; Gregorich, Zachery R.; Ge, Ying

2014-03-01

57

Normative Data for a User-friendly Paradigm for Pattern Electroretinogram Recording  

PubMed Central

Purpose To provide normative data for a user-friendly paradigm for the pattern electroretinogram (PERG) optimized for glaucoma screening (PERGLA). Design Prospective nonrandomized case series. Participants Ninety-three normal subjects ranging in age between 22 and 85 years. Methods A circular black–white grating of 25° visual angle, reversing 16.28 times per second, was presented on a television monitor placed inside a Ganzfeld bowl. The PERG was recorded simultaneously from both eyes with undilated pupils by means of skin cup electrodes taped over the lower eyelids. Reference electrodes were taped on the ipsilateral temples. Electrophysiologic signals were conventionally amplified, filtered, and digitized. Six hundred artifact-free repetitions were averaged. The response component at the reversal frequency was isolated automatically by digital Fourier transforms and was expressed as a deviation from the age-corrected average. The procedure took approximately 4 minutes. Main Outcome Measures Pattern electroretinogram amplitude (?V) and phase (? rad); response variability (coefficient of variation [CV] = standard deviation [SD] / mean × 100) of amplitude and phase of 2 partial averages that build up the PERG waveform; amplitude (?V) of background noise waveform, obtained by multiplying alternate sweeps by +1 and ?1; and interocular asymmetry (CV of amplitude and phase of the PERG of the 2 eyes). Results On average, the PERG has a signal-to-noise ratio of more than 13:1. The CVs of intrasession and intersession variabilities in amplitude and phase are lower than 10% and 2%, respectively, and do not depend on the operator. The CV of interocular asymmetries in amplitude and phase are 9.8±8.8% and 1.5±1.4%, respectively. The PERG amplitude and phase decrease with age. Residuals of linear regression lines have normal distribution, with an SD of 0.1 log units for amplitude and 0.019 log units for phase. Age-corrected confidence limits (P<0.05) are defined as ±2 SD of residuals. Conclusions The PERGLA paradigm yields responses as reliable as the best previously reported using standard protocols. The ease of execution and interpretation of results of PERGLA indicate a potential value for objective screening and follow-up of glaucoma.

Porciatti, Vittorio; Ventura, Lori M.

2009-01-01

58

The Clinical Ethnographic Interview: A user-friendly guide to the cultural formulation of distress and help seeking  

PubMed Central

Transcultural nursing, psychiatry, and medical anthropology have theorized that practitioners and researchers need more flexible instruments to gather culturally relevant illness experience, meaning, and help seeking. The state of the science is sufficiently developed to allow standardized yet ethnographically sound protocols for assessment. However, vigorous calls for culturally adapted assessment models have yielded little real change in routine practice. This paper describes the conversion of the Diagnostic and Statistical Manual IV, Appendix I Outline for Cultural Formulation into a user-friendly Clinical Ethnographic Interview (CEI), and provides clinical examples of its use in a sample of highly distressed Japanese women.

Arnault, Denise Saint; Shimabukuro, Shizuka

2013-01-01

59

Wordom: A User-Friendly Program for the Analysis of Molecular Structures, Trajectories, and Free Energy Surfaces  

PubMed Central

Wordom is a versatile, user-friendly, and efficient program for manipulation and analysis of molecular structures and dynamics. The following new analysis modules have been added since the publication of the original Wordom paper in 2007: assignment of secondary structure, calculation of solvent accessible surfaces, elastic network model, motion cross correlations, protein structure network, shortest intra-molecular and inter-molecular communication paths, kinetic grouping analysis, and calculation of mincut-based free energy profiles. In addition, an interface with the Python scripting language has been built and the overall performance and user accessibility enhanced. The source code of Wordom (in the C programming language) as well as documentation for usage and further development are available as an open source package under the GNU General Purpose License from http://wordom.sf.net. © 2010 Wiley Periodicals, Inc. J Comput Chem, 2011

Seeber, Michele; Felline, Angelo; Raimondi, Francesco; Muff, Stefanie; Friedman, Ran; Rao, Francesco; Caflisch, Amedeo; Fanelli, Francesca

2011-01-01

60

Short Communication: TopoToolbox 2 - an efficient and user-friendly tool for Earth surface sciences  

NASA Astrophysics Data System (ADS)

TopoToolbox is a MATLAB software for the analysis of digital elevation models (DEMs). With the release of version 2, the software adopts an Object-Oriented Programming (OOP) approach to work with gridded DEMs, and derived data such as flow directions and stream networks. The introduction of a novel technique to store flow directions as topologically ordered vectors of indices allows for easy coding, increased processing speed and reduction in memory overhead. Graphical user interfaces enable visual exploration and interaction with DEMs and derivatives and provide access to tools targeted at fluvial and tectonic geomorphologists. With this new release, TopoToolbox has become a more memory efficient, faster and more user-friendly tool for digital terrain analysis that can be used as a framework for building hydrological and geomorphological models in MATLAB.

Schwanghart, W.; Scherler, D.

2013-08-01

61

Colorado Late Cenozoic Fault and Fold Database and Internet Map Server: User-friendly technology for complex information  

USGS Publications Warehouse

Internet mapping applications for geologic data allow simultaneous data delivery and collection, enabling quick data modification while efficiently supplying the end user with information. Utilizing Web-based technologies, the Colorado Geological Survey's Colorado Late Cenozoic Fault and Fold Database was transformed from a monothematic, nonspatial Microsoft Access database into a complex information set incorporating multiple data sources. The resulting user-friendly format supports easy analysis and browsing. The core of the application is the Microsoft Access database, which contains information compiled from available literature about faults and folds that are known or suspected to have moved during the late Cenozoic. The database contains nonspatial fields such as structure type, age, and rate of movement. Geographic locations of the fault and fold traces were compiled from previous studies at 1:250,000 scale to form a spatial database containing information such as length and strike. Integration of the two databases allowed both spatial and nonspatial information to be presented on the Internet as a single dataset (http://geosurvey.state.co.us/pubs/ceno/). The user-friendly interface enables users to view and query the data in an integrated manner, thus providing multiple ways to locate desired information. Retaining the digital data format also allows continuous data updating and quick delivery of newly acquired information. This dataset is a valuable resource to anyone interested in earthquake hazards and the activity of faults and folds in Colorado. Additional geologic hazard layers and imagery may aid in decision support and hazard evaluation. The up-to-date and customizable maps are invaluable tools for researchers or the public.

Morgan, K. S.; Pattyn, G. J.; Morgan, M. L.

2005-01-01

62

Back to BaySICS: A User-Friendly Program for Bayesian Statistical Inference from Coalescent Simulations  

PubMed Central

Inference of population demographic history has vastly improved in recent years due to a number of technological and theoretical advances including the use of ancient DNA. Approximate Bayesian computation (ABC) stands among the most promising methods due to its simple theoretical fundament and exceptional flexibility. However, limited availability of user-friendly programs that perform ABC analysis renders it difficult to implement, and hence programming skills are frequently required. In addition, there is limited availability of programs able to deal with heterochronous data. Here we present the software BaySICS: Bayesian Statistical Inference of Coalescent Simulations. BaySICS provides an integrated and user-friendly platform that performs ABC analyses by means of coalescent simulations from DNA sequence data. It estimates historical demographic population parameters and performs hypothesis testing by means of Bayes factors obtained from model comparisons. Although providing specific features that improve inference from datasets with heterochronous data, BaySICS also has several capabilities making it a suitable tool for analysing contemporary genetic datasets. Those capabilities include joint analysis of independent tables, a graphical interface and the implementation of Markov-chain Monte Carlo without likelihoods.

Sandoval-Castellanos, Edson; Palkopoulou, Eleftheria; Dalen, Love

2014-01-01

63

Integration of pre-aligned liquid metal electrodes for neural stimulation within a user-friendly microfluidic platform.  

PubMed

Electrical stimulation of nervous tissue is used clinically for the treatment of multiple neurological disorders and experimentally for basic research. With the increase of optical probes to record neuronal activity, simple and user-friendly methods are desired to stimulate neurons and their subcellular compartments for biological experimentation. Here we describe the novel integration of liquid metal electrodes with microfluidic culture platforms to accomplish this goal. We integrated electrode and cell channels into a single poly(dimethylsiloxane) (PDMS) chip, eliminating entirely the need to align electrodes with microchannels. We designed the electrode channels such that the metal can be injected by hand and when the device is non-covalently bound to glass. We demonstrated the biocompatibility of the electrodes for long-term cultures (12 days) using hippocampal neurons. We demonstrated the use of these electrodes to depolarize neurons and recorded neuronal activity using the calcium indicator dye, Fluo-4. We established optimal stimulation parameters that induce neuronal spiking without inducing damage. We showed that the liquid metal electrode evoked larger calcium responses in somata than bath electrodes using the same stimulus parameters. Lastly we demonstrated the use of these liquid metal electrodes to target and depolarize axons. In summary, the integration of liquid metal electrodes with neuronal culture platforms provides a user-friendly and targeted method to stimulate neurons and their subcellular compartments, thus providing a novel tool for future biological investigations. PMID:23232866

Hallfors, Nicholas; Khan, Asif; Dickey, Michael D; Taylor, Anne Marion

2013-02-21

64

MOO in Your Face: Researching, Designing, and Programming a User-Friendly Interface.  

ERIC Educational Resources Information Center

Suggests the learning curve of a multi-user, object-oriented domain (MOO) blockades effective use. Discusses use of an IBM/PC-compatible interface that allows developers to modify the interface to provide a sense of presence for the user. Concludes that work in programming a variety of interfaces has led to a more intuitive environment for…

Haas, Mark; Gardner, Clinton

1999-01-01

65

GProX, a User-Friendly Platform for Bioinformatics Analysis and Visualization of Quantitative Proteomics Data*  

PubMed Central

Recent technological advances have made it possible to identify and quantify thousands of proteins in a single proteomics experiment. As a result of these developments, the analysis of data has become the bottleneck of proteomics experiment. To provide the proteomics community with a user-friendly platform for comprehensive analysis, inspection and visualization of quantitative proteomics data we developed the Graphical Proteomics Data Explorer (GProX)1. The program requires no special bioinformatics training, as all functions of GProX are accessible within its graphical user-friendly interface which will be intuitive to most users. Basic features facilitate the uncomplicated management and organization of large data sets and complex experimental setups as well as the inspection and graphical plotting of quantitative data. These are complemented by readily available high-level analysis options such as database querying, clustering based on abundance ratios, feature enrichment tests for e.g. GO terms and pathway analysis tools. A number of plotting options for visualization of quantitative proteomics data is available and most analysis functions in GProX create customizable high quality graphical displays in both vector and bitmap formats. The generic import requirements allow data originating from essentially all mass spectrometry platforms, quantitation strategies and software to be analyzed in the program. GProX represents a powerful approach to proteomics data analysis providing proteomics experimenters with a toolbox for bioinformatics analysis of quantitative proteomics data. The program is released as open-source and can be freely downloaded from the project webpage at http://gprox.sourceforge.net.

Rigbolt, Kristoffer T. G.; Vanselow, Jens T.; Blagoev, Blagoy

2011-01-01

66

User-Friendly Data Servers for Climate Studies at the Asia-Pacific Data-Research Center (APDRC)  

NASA Astrophysics Data System (ADS)

The APDRC was recently established within the International Pacific Research Center (IPRC) at the University of Hawaii. The APDRC mission is to increase understanding of climate variability in the Asia-Pacific region by developing the computational, data-management, and networking infrastructure necessary to make data resources readily accessible and usable by researchers, and by undertaking data-intensive research activities that will both advance knowledge and lead to improvements in data preparation and data products. A focus of recent activity is the implementation of user-friendly data servers. The APDRC is currently running a Live Access Server (LAS) developed at NOAA/PMEL to provide access to and visualization of gridded climate products via the web. The LAS also allows users to download the selected data subsets in various formats (such as binary, netCDF and ASCII). Most of the datasets served by the LAS are also served through our OPeNDAP server (formerly DODS), which allows users to directly access the data using their desktop client tools (e.g. GrADS, Matlab and Ferret). In addition, the APDRC is running an OPeNDAP Catalog/Aggregation Server (CAS) developed by Unidata at UCAR to serve climate data and products such as model output and satellite-derived products. These products are often large (> 2 GB) and are therefore stored as multiple files (stored separately in time or in parameters). The CAS remedies the inconvenience of multiple files and allows access to the whole dataset (or any subset that cuts across the multiple files) via a single request command from any DODS enabled client software. Once the aggregation of files is configured at the server (CAS), the process of aggregation is transparent to the user. The user only needs to know a single URL for the entire dataset, which is, in fact, stored as multiple files. CAS even allows aggregation of files on different systems and at different locations. Currently, the APDRC is serving NCEP, ECMWF, SODA, WOCE-Satellite, TMI, GPI and GSSTF products through the CAS. The APDRC is also running an EPIC server developed by PMEL/NOAA. EPIC is a web-based, data search and display system suited for in situ (station versus gridded) data. The process of locating and selecting individual station data from large collections (millions of profiles or time series, etc.) of in situ data is a major challenge. Serving in situ data on the Internet faces two problems: the irregularity of data formats; and the large quantity of data files. To solve the first problem, we have converted the in situ data into netCDF data format. The second problem was solved by using the EPIC server, which allows users to easily subset the files using a friendly graphical interface. Furthermore, we enhanced the capability of EPIC and configured OPeNDAP into EPIC to serve the numerous in situ data files and to export them to users through two different options: 1) an OPeNDAP pointer file of user-selected data files; and 2) a data package that includes meta-information (e.g., location, time, cruise no, etc.), a local pointer file, and the data files that the user selected. Option 1) is for those who do not want to download the selected data but want to use their own application software (such as GrADS, Matlab and Ferret) for access and analysis; option 2) is for users who want to store the data on their own system (e.g. laptops before going for a cruise) for subsequent analysis. Currently, WOCE CTD and bottle data, the WOCE current meter data, and some Argo float data are being served on the EPIC server.

Yuan, G.; Shen, Y.; Zhang, Y.; Merrill, R.; Waseda, T.; Mitsudera, H.; Hacker, P.

2002-12-01

67

A user-friendly, graphical interface for the Monte Carlo neutron optics code MCLIB  

SciTech Connect

The authors describe a prototype of a new user interface for the Monte Carlo neutron optics simulation program MCLIB. At this point in its development the interface allows the user to define an instrument as a set of predefined instrument elements. The user can specify the intrinsic parameters of each element, its position and orientation. The interface then writes output to the MCLIB package and starts the simulation. The present prototype is an early development stage of a comprehensive Monte Carlo simulations package that will serve as a tool for the design, optimization and assessment of performance of new neutron scattering instruments. It will be an important tool for understanding the efficacy of new source designs in meeting the needs of these instruments.

Thelliez, T.; Daemen, L.; Hjelm, R.P. [Los Alamos National Lab., NM (United States); Seeger, P.A. [Seeger (Phil A.), Los Alamos, NM (United States)

1995-12-01

68

Towards User-Friendly Spelling with an Auditory Brain-Computer Interface: The CharStreamer Paradigm  

PubMed Central

Realizing the decoding of brain signals into control commands, brain-computer interfaces (BCI) aim to establish an alternative communication pathway for locked-in patients. In contrast to most visual BCI approaches which use event-related potentials (ERP) of the electroencephalogram, auditory BCI systems are challenged with ERP responses, which are less class-discriminant between attended and unattended stimuli. Furthermore, these auditory approaches have more complex interfaces which imposes a substantial workload on their users. Aiming for a maximally user-friendly spelling interface, this study introduces a novel auditory paradigm: “CharStreamer”. The speller can be used with an instruction as simple as “please attend to what you want to spell”. The stimuli of CharStreamer comprise 30 spoken sounds of letters and actions. As each of them is represented by the sound of itself and not by an artificial substitute, it can be selected in a one-step procedure. The mental mapping effort (sound stimuli to actions) is thus minimized. Usability is further accounted for by an alphabetical stimulus presentation: contrary to random presentation orders, the user can foresee the presentation time of the target letter sound. Healthy, normal hearing users (n?=?10) of the CharStreamer paradigm displayed ERP responses that systematically differed between target and non-target sounds. Class-discriminant features, however, varied individually from the typical N1-P2 complex and P3 ERP components found in control conditions with random sequences. To fully exploit the sequential presentation structure of CharStreamer, novel data analysis approaches and classification methods were introduced. The results of online spelling tests showed that a competitive spelling speed can be achieved with CharStreamer. With respect to user rating, it clearly outperforms a control setup with random presentation sequences.

Hohne, Johannes; Tangermann, Michael

2014-01-01

69

Towards User-Friendly Spelling with an Auditory Brain-Computer Interface: The CharStreamer Paradigm.  

PubMed

Realizing the decoding of brain signals into control commands, brain-computer interfaces (BCI) aim to establish an alternative communication pathway for locked-in patients. In contrast to most visual BCI approaches which use event-related potentials (ERP) of the electroencephalogram, auditory BCI systems are challenged with ERP responses, which are less class-discriminant between attended and unattended stimuli. Furthermore, these auditory approaches have more complex interfaces which imposes a substantial workload on their users. Aiming for a maximally user-friendly spelling interface, this study introduces a novel auditory paradigm: "CharStreamer". The speller can be used with an instruction as simple as "please attend to what you want to spell". The stimuli of CharStreamer comprise 30 spoken sounds of letters and actions. As each of them is represented by the sound of itself and not by an artificial substitute, it can be selected in a one-step procedure. The mental mapping effort (sound stimuli to actions) is thus minimized. Usability is further accounted for by an alphabetical stimulus presentation: contrary to random presentation orders, the user can foresee the presentation time of the target letter sound. Healthy, normal hearing users (n?=?10) of the CharStreamer paradigm displayed ERP responses that systematically differed between target and non-target sounds. Class-discriminant features, however, varied individually from the typical N1-P2 complex and P3 ERP components found in control conditions with random sequences. To fully exploit the sequential presentation structure of CharStreamer, novel data analysis approaches and classification methods were introduced. The results of online spelling tests showed that a competitive spelling speed can be achieved with CharStreamer. With respect to user rating, it clearly outperforms a control setup with random presentation sequences. PMID:24886978

Höhne, Johannes; Tangermann, Michael

2014-01-01

70

MINErosion 3: A user friendly hillslope model for predicting erosion from steep post-mining landscapes in Central Queensland, Australia.  

NASA Astrophysics Data System (ADS)

Open-cut coal mining in Central Queensland involves the breaking up of overburden that overlies the coal seams using explosives, followed by removal with draglines which results in the formation of extensive overburden spoil-piles with steep slopes at the angle of repose (approximately 75 % or 37o). These spoil-piles are found in long multiple rows, with heights of up to 60 or 70 m above the original landscapes. They are generally highly saline and dispersive and hence highly erosive. Legislation requires that these spoil-piles be rehabilitated into a stable self sustaining ecosystem with no off-site pollution. The first stage in the rehabilitation of these landscapes is the lowering of slopes to create a landscape that is stable against geotechnical failure and erosion. This is followed by revegetation generally with grasses as pioneer vegetation to further reduce erosion and a mixture of native shrubs and trees. Minimizing erosion and excessive on-site discharges of sediment into the working areas may result in the temporary cessation of mining operation with significant financial consequences, while off site discharges may breach the mining lease conditions. The average cost of rehabilitation is around 22,000 per ha. With more than 50,000 ha of such spoil-piles in Queensland at present, the total cost of rehabilitation facing the industry is very high. Most of this comprised the cost of reshaping the landscape, largely associated with the amount of material movement necessary to achieve the desired landscape. Since soil and spoil-piles vary greatly in their erodibilities, a reliable and accurate method is required to determine a cost effective combination of slope length, slope gradient and vegetation that will result in acceptable rates of erosion. A user friendly hillslope computer package MINErosion 3, was developed to predict potential erosion to select suitable combinations of landscape design parameters (slope gradient, slope length and vegetation cover) that will result in acceptable rates of erosion. Slope length and gradient can then be used by the mining companies as inputs into their landscape design software to cost effectively construct suitable landscapes that will meet the required erosion criteria. MINErosion 3 itself is a cost effective package as it used laboratory derived parameters as inputs and predicts both the field annual average soil loss under the prevailing climatic conditions (using RUSLE) as well as the potential erosion from individual storms with known recurrent intervals (using MUSLE). MINErosion 3 is very simple and easy to use and the data requirements are small. A database of 34 soils and spoils from Central Queensland are imbeded in the model. This paper discusses the approach adopted for this model, its features and validation against data collected using large field rainfall simulators as well as field runoff plots ranging from 20 to 120 m long at different slope gradients from 10 to 75 %. The agreement between predicted (Y1) and measured (X1) annual average soil loss is good with a regression equation of Y1 = 0.8 X1 + 0.005 and an R2 = 0.70; while predicted (Y2) and measured (X2) rainstorm erosion events have a regression of Y2 = 0.867 X2 with an R2 of 0.68.

So, Hwat-Bing; Khalifa, Ashraf; Carroll, Chris; Yu, Bofu

2010-05-01

71

Joyce and Ulysses: integrated and user-friendly tools for the parameterization of intramolecular force fields from quantum mechanical data.  

PubMed

The Joyce program is augmented with several new features, including the user friendly Ulysses GUI, the possibility of complete excited state parameterization and a more flexible treatment of the force field electrostatic terms. A first validation is achieved by successfully comparing results obtained with Joyce2.0 to literature ones, obtained for the same set of benchmark molecules. The parameterization protocol is also applied to two other larger molecules, namely nicotine and a coumarin based dye. In the former case, the parameterized force field is employed in molecular dynamics simulations of solvated nicotine, and the solute conformational distribution at room temperature is discussed. Force fields parameterized with Joyce2.0, for both the dye's ground and first excited electronic states, are validated through the calculation of absorption and emission vertical energies with molecular mechanics optimized structures. Finally, the newly implemented procedure to handle polarizable force fields is discussed and applied to the pyrimidine molecule as a test case. PMID:23389748

Barone, Vincenzo; Cacelli, Ivo; De Mitri, Nicola; Licari, Daniele; Monti, Susanna; Prampolini, Giacomo

2013-03-21

72

SPCDC: A user-friendly computational tool for the design and refinement of practical pulse combustion systems  

SciTech Connect

This paper reports on the development and use of a user-friendly, PC-executable computer code that can assist engineers in designing pulse combustors for specific applications and in refining existing units. This code represents the culmination of over 10 years of research and development in the field of pulse combustion. The Sandia Pulse Combustor Design Code, or SPCDC, couples both the fuel-air injection and the energy release to the time-varying pressure wave. Because the injection and combustion processes both drive and are driven by the wave dynamics, this model couples the major processes that occur in a pulse combustor. SPCDC can supplement the time-proven method of actually building and testing a prototype unit, and significantly reduce the number of units that must be tested. It will help produce a superior pulse combustion system tailored to a specific application and should help widen the range of successful applications.

Barr, P.K.; Keller, J.O. [Sandia National Labs., Albuquerque, NM (United States); Kezerle, J.A. [Gas Research Institute (United States)

1995-07-01

73

What Do You Mean by "User-Friendly"?: Pre-Service Teachers Evaluate Language Software.  

ERIC Educational Resources Information Center

A survey of 24 English-as-a-Second-Language teacher trainees in Singapore elicited their top five criteria for evaluating language-learning software and their interpretations and understanding of one criterion, "user-friendliness." It was found that in general, this was the first criterion listed for software evaluation; the others were, in…

Cheah, Yin Mee; Cheung, Wing Sum

74

Morpheus: a user-friendly modeling environment for multiscale and multicellular systems biology.  

PubMed

Morpheus is a modeling environment for the simulation and integration of cell-based models with ordinary differential equations and reaction-diffusion systems. It allows rapid development of multiscale models in biological terms and mathematical expressions rather than programming code. Its graphical user interface supports the entire workflow from model construction and simulation to visualization, archiving and batch processing. PMID:24443380

Starruß, Jörn; de Back, Walter; Brusch, Lutz; Deutsch, Andreas

2014-05-01

75

SLEM (SLAVE Emulator Editor): A user-friendly, advanced text editor  

SciTech Connect

SLEM is a new full-screen editor for VAX/VMS computers which is programmed in the VAXTPU language. In addition to executing more quickly than EDT, SLEM proviees several new, advanced features while employing a user interface which is similar to EDT. The SLEM enhancements in the VAXTPU facility are like the SLAVE editor enhancements to EDT.

Mills-Curran, W.C.

1986-11-01

76

DEDIP: a user-friendly environment for digital image processing algorithm development  

Microsoft Academic Search

The DEDIP (developmental environment for digital image processing) system is a simple environment for the development of digital image processing applications. It consists of two user interface levels. The low level is compiled software library of digital image processing and system management functions. The high level is a command line interpreter with a set of digital image processing and file

W. A. Keddy; P. Agathoklis

1991-01-01

77

User-friendly interfaces for control of crystallographic experiments at CHESS  

SciTech Connect

In designing a system to collect high quality diffraction data in an efficient manner, both hardware and software must be considered. This work focuses on the data collection software used at CHESS, the Cornell High Energy Synchrotron source, with emphasis on the interface between the user and the experimental components. For each type of detector used at CHESS, there is a graphical user interface (GUI) enabling the user to easily set up and run an experiment. For the CCD detector from Area Detector Systems Corp., this is a commercial product from ADSC, customized for CHESS. For the Princeton CCD detectors, a GUI has recently been developed to streamline communication between the user and the TV6 program which controls the detector. For Fuji imaging plates, a new GUI controls operation of the oscillation camera, including the imaging plate carousel; scanning of plates is done using the software provided by Fuji. Although these GUI's are not identical, they have numerous similarities, making it easier for users to learn operation of a new detector. They also incorporate error-checking to avoid problems such as overwriting data files or collecting data with no x-rays. Common to experiments with all detectors is a GUI used for operations such as alignment of the optical table on which the oscillation camera is mounted. Integral to a good data collection system is the capability to process diffraction images, for evaluation of crystal quality, determination of data collection strategy, screening of potential derivatives, and so forth. The mccview graphical front-end has been developed to conveniently initiate processing programs, including preliminary routines (correct, getbeam), main analysis routines (xdisp, denzo, scalepack), and the strategy routine m.simulate.

Szebenyi, D. M. E.; Deacon, A.; Ealick, S. E.; LaIuppa, J. M.; Thiel, D. J. [MacCHESS, Cornell University, Ithaca, New York 14853 (United States)

1997-07-01

78

PREPAR: a user-friendly preprocessor to create AIRDOS-EPA input data sets  

SciTech Connect

PREPAR is a FORTRAN program designed to simplify the preparation of input for the AIRDOS-EPA computer code. PREPAR was designed to provide a method for data entry that is both logical and flexible. It also provides default values for all variables, so the user needs only to enter those data for which the defaults should be changed. Data are entered either unformatted or via a user-selected format. A separate file of the nuclide-specific data needed by AIRDOS-EPA is read by PREPAR. Two utility programs, EXTRAC and RADLST, were written to create and list this file. PREPAR writes the file needed to run AIRDOS-EPA and writes a listing of that file.

Sjoreen, A.L.; Miller, C.W.; Nelson, C.B.

1984-01-01

79

An interactive user-friendly approach to surface-fitting three-dimensional geometries  

NASA Technical Reports Server (NTRS)

A surface-fitting technique has been developed which addresses two problems with existing geometry packages: computer storage requirements and the time required of the user for the initial setup of the geometry model. Coordinates of cross sections are fit using segments of general conic sections. The next step is to blend the cross-sectional curve-fits in the longitudinal direction using general conics to fit specific meridional half-planes. Provisions are made to allow the fitting of fuselages and wings so that entire wing-body combinations may be modeled. This report includes the development of the technique along with a User's Guide for the various menus within the program. Results for the modeling of the Space Shuttle and a proposed Aeroassist Flight Experiment geometry are presented.

Cheatwood, F. Mcneil; Dejarnette, Fred R.

1988-01-01

80

Brainstorm: A User-Friendly Application for MEG/EEG Analysis  

PubMed Central

Brainstorm is a collaborative open-source application dedicated to magnetoencephalography (MEG) and electroencephalography (EEG) data visualization and processing, with an emphasis on cortical source estimation techniques and their integration with anatomical magnetic resonance imaging (MRI) data. The primary objective of the software is to connect MEG/EEG neuroscience investigators with both the best-established and cutting-edge methods through a simple and intuitive graphical user interface (GUI).

Tadel, Francois; Baillet, Sylvain; Mosher, John C.; Pantazis, Dimitrios; Leahy, Richard M.

2011-01-01

81

Blink 'Em All: Scalable, User-Friendly and Secure Initialization of Wireless Sensor Nodes  

Microsoft Academic Search

Wireless sensor networks have several useful applications in commer- cial and defense settings, as well as user-centric personal area networks. To es- tablish secure (point-to-point and\\/or broadcast) communication channels among the nodes of a wireless sensor network is a fundamental security task. To this end, a plethora of so-called key pre-distribution schemes have been proposed in the past, e.g., (25)(9)(19)(8)(5).

Nitesh Saxena

2009-01-01

82

A user-friendly, open-source tool to project impact and cost of diagnostic tests for tuberculosis  

PubMed Central

Most models of infectious diseases, including tuberculosis (TB), do not provide results customized to local conditions. We created a dynamic transmission model to project TB incidence, TB mortality, multidrug-resistant (MDR) TB prevalence, and incremental costs over 5 years after scale-up of nine alternative diagnostic strategies. A corresponding web-based interface allows users to specify local costs and epidemiology. In settings with little capacity for up-front investment, same-day microscopy had the greatest impact on TB incidence and became cost-saving within 5 years if delivered at $10/test. With greater initial investment, population-level scale-up of Xpert MTB/RIF or microcolony-based culture often averted 10 times more TB cases than narrowly-targeted strategies, at minimal incremental long-term cost. Xpert for smear-positive TB had reasonable impact on MDR-TB incidence, but at substantial price and little impact on overall TB incidence and mortality. This user-friendly modeling framework improves decision-makers' ability to evaluate the local impact of TB diagnostic strategies. DOI: http://dx.doi.org/10.7554/eLife.02565.001

Dowdy, David W; Andrews, Jason R; Dodd, Peter J; Gilman, Robert H

2014-01-01

83

A user-friendly SSVEP-based brain-computer interface using a time-domain classifier  

NASA Astrophysics Data System (ADS)

We introduce a user-friendly steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) system. Single-channel EEG is recorded using a low-noise dry electrode. Compared to traditional gel-based multi-sensor EEG systems, a dry sensor proves to be more convenient, comfortable and cost effective. A hardware system was built that displays four LED light panels flashing at different frequencies and synchronizes with EEG acquisition. The visual stimuli have been carefully designed such that potential risk to photosensitive people is minimized. We describe a novel stimulus-locked inter-trace correlation (SLIC) method for SSVEP classification using EEG time-locked to stimulus onsets. We studied how the performance of the algorithm is affected by different selection of parameters. Using the SLIC method, the average light detection rate is 75.8% with very low error rates (an 8.4% false positive rate and a 1.3% misclassification rate). Compared to a traditional frequency-domain-based method, the SLIC method is more robust (resulting in less annoyance to the users) and is also suitable for irregular stimulus patterns.

Luo, An; Sullivan, Thomas J.

2010-04-01

84

A user-friendly SSVEP-based brain-computer interface using a time-domain classifier.  

PubMed

We introduce a user-friendly steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI) system. Single-channel EEG is recorded using a low-noise dry electrode. Compared to traditional gel-based multi-sensor EEG systems, a dry sensor proves to be more convenient, comfortable and cost effective. A hardware system was built that displays four LED light panels flashing at different frequencies and synchronizes with EEG acquisition. The visual stimuli have been carefully designed such that potential risk to photosensitive people is minimized. We describe a novel stimulus-locked inter-trace correlation (SLIC) method for SSVEP classification using EEG time-locked to stimulus onsets. We studied how the performance of the algorithm is affected by different selection of parameters. Using the SLIC method, the average light detection rate is 75.8% with very low error rates (an 8.4% false positive rate and a 1.3% misclassification rate). Compared to a traditional frequency-domain-based method, the SLIC method is more robust (resulting in less annoyance to the users) and is also suitable for irregular stimulus patterns. PMID:20332551

Luo, An; Sullivan, Thomas J

2010-04-01

85

Morpheus: a user-friendly modeling environment for multiscale and multicellular systems biology  

PubMed Central

Summary: Morpheus is a modeling environment for the simulation and integration of cell-based models with ordinary differential equations and reaction-diffusion systems. It allows rapid development of multiscale models in biological terms and mathematical expressions rather than programming code. Its graphical user interface supports the entire workflow from model construction and simulation to visualization, archiving and batch processing. Availability and implementation: Binary packages are available at http://imc.zih.tu-dresden.de/wiki/morpheus for Linux, Mac OSX and MS Windows. Contact: walter.deback@tu-dresden.de Supplementary information: Supplementary data are available at Bioinformatics online.

Starruss, Jorn; de Back, Walter; Brusch, Lutz; Deutsch, Andreas

2014-01-01

86

A user-friendly menu-driven language-free laser characteristics curves graphing program  

NASA Technical Reports Server (NTRS)

In the selection of laser materials to be used as active sensors, it is essential to know how various factors of the specific material composition interact. Questions such as how does the rod size and frequency or absorption relate and how might this be affected by temperature variations must be answered before the materials are selected. A menu-driven language-free program was developed that would graph the interrelationship of many physical parameters of laser materials. This program reduced or removed the requirement that all users be competent in FORTRAN. A menu-driven language-free program was then developed that requires the use of a microcomputer to graph a two-dimensional display of data. The ability to graph more than one graph-line on the same chart was accomplished. The program is now generic in that it will take any data file whether in the data base or not. The program generates the format for the data read statement if it is not contained in the file header and the user does not know how to write them.

Klutz, Glenn

1990-01-01

87

BioAssemblyModeler (BAM): User-Friendly Homology Modeling of Protein Homo- and Heterooligomers.  

PubMed

Many if not most proteins function in oligomeric assemblies of one or more protein sequences. The Protein Data Bank provides coordinates for biological assemblies for each entry, at least 60% of which are dimers or larger assemblies. BioAssemblyModeler (BAM) is a graphical user interface to the basic steps in homology modeling of protein homooligomers and heterooligomers from the biological assemblies provided in the PDB. BAM takes as input up to six different protein sequences and begins by assigning Pfam domains to the target sequences. The program utilizes a complete assignment of Pfam domains to sequences in the PDB, PDBfam (http://dunbrack2.fccc.edu/protcid/pdbfam), to obtain templates that contain any or all of the domains assigned to the target sequence(s). The contents of the biological assemblies of potential templates are provided, and alignments of the target sequences to the templates are produced with a profile-profile alignment algorithm. BAM provides for visual examination and mouse-editing of the alignments supported by target and template secondary structure information and a 3D viewer of the template biological assembly. Side-chain coordinates for a model of the biological assembly are built with the program SCWRL4. A built-in protocol navigation system guides the user through all stages of homology modeling from input sequences to a three-dimensional model of the target complex. Availability: http://dunbrack.fccc.edu/BAM. PMID:24922057

Shapovalov, Maxim V; Wang, Qiang; Xu, Qifang; Andrake, Mark; Dunbrack, Roland L

2014-01-01

88

BioAssemblyModeler (BAM): User-Friendly Homology Modeling of Protein Homo- and Heterooligomers  

PubMed Central

Many if not most proteins function in oligomeric assemblies of one or more protein sequences. The Protein Data Bank provides coordinates for biological assemblies for each entry, at least 60% of which are dimers or larger assemblies. BioAssemblyModeler (BAM) is a graphical user interface to the basic steps in homology modeling of protein homooligomers and heterooligomers from the biological assemblies provided in the PDB. BAM takes as input up to six different protein sequences and begins by assigning Pfam domains to the target sequences. The program utilizes a complete assignment of Pfam domains to sequences in the PDB, PDBfam (http://dunbrack2.fccc.edu/protcid/pdbfam), to obtain templates that contain any or all of the domains assigned to the target sequence(s). The contents of the biological assemblies of potential templates are provided, and alignments of the target sequences to the templates are produced with a profile-profile alignment algorithm. BAM provides for visual examination and mouse-editing of the alignments supported by target and template secondary structure information and a 3D viewer of the template biological assembly. Side-chain coordinates for a model of the biological assembly are built with the program SCWRL4. A built-in protocol navigation system guides the user through all stages of homology modeling from input sequences to a three-dimensional model of the target complex. Availability: http://dunbrack.fccc.edu/BAM.

Xu, Qifang; Andrake, Mark; Dunbrack, Roland L.

2014-01-01

89

CO2calc: A User Friendly Seawater Carbon Calculator for Windows, Mac OS X, and iOS (iPhone).  

National Technical Information Service (NTIS)

A user-friendly, stand-alone application for the calculation of carbonate system parameters was developed by the U.S. Geological Survey Florida Shelf Ecosystems Response to Climate Change Project in response to its Ocean Acidification Task. The applicatio...

J. A. Kleypas L. L. Robbins M. E. Hansen S. C. Meylan

2010-01-01

90

The VERCE Science Gateway: enabling user friendly seismic waves simulations across European HPC infrastructures  

NASA Astrophysics Data System (ADS)

The EU-funded project VERCE (Virtual Earthquake and seismology Research Community in Europe) aims to deploy technologies which satisfy the HPC and data-intensive requirements of modern seismology. As a result of VERCE's official collaboration with the EU project SCI-BUS, access to computational resources, like local clusters and international infrastructures (EGI and PRACE), is made homogeneous and integrated within a dedicated science gateway based on the gUSE framework. In this presentation we give a detailed overview on the progress achieved with the developments of the VERCE Science Gateway, according to a use-case driven implementation strategy. More specifically, we show how the computational technologies and data services have been integrated within a tool for Seismic Forward Modelling, whose objective is to offer the possibility to perform simulations of seismic waves as a service to the seismological community. We will introduce the interactive components of the OGC map based web interface and how it supports the user with setting up the simulation. We will go through the selection of input data, which are either fetched from federated seismological web services, adopting community standards, or provided by the users themselves by accessing their own document data store. The HPC scientific codes can be selected from a number of waveform simulators, currently available to the seismological community as batch tools or with limited configuration capabilities in their interactive online versions. The results will be staged out from the HPC via a secure GridFTP transfer to a VERCE data layer managed by iRODS. The provenance information of the simulation will be automatically cataloged by the data layer via NoSQL techonologies. We will try to demonstrate how data access, validation and visualisation can be supported by a general purpose provenance framework which, besides common provenance concepts imported from the OPM and the W3C-PROV initiatives, also offers an extensible metadata archive including community and user defined metadata and annotations. Finally, we will show how the VERCE Gateway platform will allow the customisation of pre and post processing phases of the simulation workflows, thanks to the availability of a registry of processing elements (PEs,) which are easily developed and maintained by the seismologists.

Spinuso, Alessandro; Krause, Amy; Ramos Garcia, Cląudia; Casarotti, Emanuele; Magnoni, Federica; Klampanos, Iraklis A.; Frobert, Laurent; Krischer, Lion; Trani, Luca; David, Mario; Leong, Siew Hoon; Muraleedharan, Visakh

2014-05-01

91

User-friendly tools on handheld devices for observer performance study  

NASA Astrophysics Data System (ADS)

ROC studies require complex procedures to select cases from many data samples, and to set confidence levels in each selected case to generate ROC curves. In some observer performance studies, researchers have to develop software with specific graphical user interface (GUI) to obtain confidence levels from readers. Because ROC studies could be designed for various clinical situations, it is difficult task for preparing software corresponding to every ROC studies. In this work, we have developed software for recording confidence levels during observer studies on tiny personal handheld devices such as iPhone, iPod touch, and iPad. To confirm the functions of our software, three radiologists performed observer studies to detect lung nodules by using public database of chest radiograms published by Japan Society of Radiological Technology. The output in text format conformed to the format for the famous ROC kit from the University of Chicago. Times required for the reading each case was recorded very precisely.

Matsumoto, Takuya; Hara, Takeshi; Shiraishi, Junji; Fukuoka, Daisuke; Abe, Hiroyuki; Matsusako, Masaki; Yamada, Akira; Zhou, Xiangrong; Fujita, Hiroshi

2012-02-01

92

A 'user friendly' geographic information system in a color interactive digital image processing system environment  

NASA Technical Reports Server (NTRS)

NASA's Eastern Regional Remote Sensing Applications Center (ERRSAC) has recognized the need to accommodate spatial analysis techniques in its remote sensing technology transfer program. A computerized Geographic Information System to incorporate remotely sensed data, specifically Landsat, with other relevant data was considered a realistic approach to address a given resource problem. Questions arose concerning the selection of a suitable available software system to demonstrate, train, and undertake demonstration projects with ERRSAC's user community. The very specific requirements for such a system are discussed. The solution found involved the addition of geographic information processing functions to the Interactive Digital Image Manipulation System (IDIMS). Details regarding the functions of the new integrated system are examined along with the characteristics of the software.

Campbell, W. J.; Goldberg, M.

1982-01-01

93

Speeding up the screening of steroids in urine: development of a user-friendly library.  

PubMed

This work presents a novel database search engine - MLibrary - designed to assist the user in the detection and identification of androgenic anabolic steroids (AAS) and its metabolites by matrix assisted laser desorption/ionization (MALDI) and mass spectrometry-based strategies. The detection of the AAS in the samples was accomplished by searching (i) the mass spectrometric (MS) spectra against the library developed to identify possible positives and (ii) by comparison of the tandem mass spectrometric (MS/MS) spectra produced after fragmentation of the possible positives with a complete set of spectra that have previously been assigned to the software. The urinary screening for anabolic agents plays a major role in anti-doping laboratories as they represent the most abused drug class in sports. With the help of the MLibrary software application, the use of MALDI techniques for doping control is simplified and the time for evaluation and interpretation of the results is reduced. To do so, the search engine takes as input several MALDI-TOF-MS and MALDI-TOF-MS/MS spectra. It aids the researcher in an automatic mode by identifying possible positives in a single MS analysis and then confirming their presence in tandem MS analysis by comparing the experimental tandem mass spectrometric data with the database. Furthermore, the search engine can, potentially, be further expanded to other compounds in addition to AASs. The applicability of the MLibrary tool is shown through the analysis of spiked urine samples. PMID:24036418

Galesio, M; López-Fdez, H; Reboiro-Jato, M; Gómez-Meire, Silvana; Glez-Peńa, D; Fdez-Riverola, F; Lodeiro, Carlos; Diniz, M E; Capelo, J L

2013-12-11

94

A user-friendly automated port placement planning system for laparoscopic robotic surgery  

NASA Astrophysics Data System (ADS)

Laparoscopic surgery is a minimally invasive surgical approach in which surgical instruments are passed through ports placed at small incisions. This approach can benefit patients by reducing recovery times and scars. Surgeons have gained greater dexterity, accuracy, and vision through adoption of robotic surgical systems. However, in some cases a preselected set of ports cannot be accommodated by the robot; the robot's arms may cause collisions during the procedure, or the surgical targets may not be reachable through the selected ports. In this case, the surgeon must either make more incisions for more ports, or even abandon the laparoscopic approach entirely. To assist in this, we are building an easytouse system which, given a surgical task and preoperative medical images of the patient, will recommend a suitable port placement plan for the robotic surgery. This work bears two main contributions: 1) a high level user interface that assists the surgeon in operating the complicated underlying planning algorithm; and 2) an interface to assist the surgical team in implementation of the recommended plan in the operating room. We believe that such an automated port placement system would reduce setup time for robotic surgery and reduce the morbidity to patients caused by unsuitable surgical port placement.

Torres, Luis G.; Azimian, Hamidreza; Enquobahrie, Andinet

2014-03-01

95

A user-friendly anisotropic flow law for ice-sheet modelling  

NASA Astrophysics Data System (ADS)

For accurate ice-sheet flow modelling, the anisotropic behaviour of ice must be taken fully into account. However, physically based micro-macro (?-M) models for the behaviour of an anisotropic ice polycrystal are too complex to be implemented easily in large-scale ice-sheet flow models. An easy and efficient method to remedy this is presented. Polar ice is assumed to behave as a linearly viscous orthotropic material whose general flow law (GOLF) depends on six parameters, and its orthotropic fabric is described by an 'orientation distribution function' (ODF) depending on two parameters. A method to pass from the ODF to a discrete description of the fabric, and vice versa, is presented. Considering any available ?-M model, the parameters of the GOLF that fit the response obtained by running this ?-M model are calculated for any set of ODF parameters. It is thus possible to tabulate the GOLF over a grid in the space of the ODF parameters. This step is performed once and for all. Ice-sheet flow models need the general form of the GOLF to be implemented in the available code (once), then, during each individual run, to retrieve the GOLF parameters from the table by interpolation. As an application example, the GOLF is tabulated using three different ?-M models and used to derive the rheological properties of ice along the Greenland Icecore Project (GRIP) ice core.

Gillet-Chaulet, Fabien; Gagliardini, Olivier; Meyssonnier, Jacques; Montagnat, Maurine; Castelnau, Olivier

96

Online user-friendly slant total electron content computation from IRI-Plas: IRI-Plas-STEC  

NASA Astrophysics Data System (ADS)

Slant total electron content (STEC), the total number of free electrons on a ray path, is an important space weather observable. STEC is the main input for computerized ionospheric tomography (CIT). STEC can be estimated using the dual-frequency GPS receivers. GPS-STEC contains the space weather variability, yet the estimates are prone to measurement and instrument errors that are not related to the physical structure of the ionosphere. International Reference Ionosphere Extended to Plasmasphere (IRI-Plas) is the international standard climatic model of ionosphere and plasmasphere, providing vertical electron density profiles for a desired date, time, and location. IRI-Plas is used as the background model in CIT. Computation of STEC from IRI-Plas is a tedious task for researchers due to extensive geodetic calculations and IRI-Plas runs. In this study, IONOLAB group introduces a new space weather service to facilitate the computation of STEC from IRI-Plas (IRI-Plas-STEC) at www.ionolab.org. The IRI-Plas-STEC can be computed online for a desired location, date, hour, elevation, and azimuth angle. The user-friendly interface also provides means for computation of IRI-STEC for a desired location and date to indicate the variability in hour of the day, elevation, or azimuth angles. The desired location can be chosen as a GPS receiver in International GNSS Service (IGS) or EUREF Permanent Network (EPN). Also instead of specifying elevation and azimuth angles, the user can directly choose from the GPS satellites and obtain IRI-Plas-STEC for a desired date and/or hour. The computed IRI-Plas-STEC values are presented directly on the screen or via e-mail as both text and plots.

Tuna, Hakan; Arikan, Orhan; Arikan, Feza; Gulyaeva, Tamara L.; Sezen, Umut

2014-01-01

97

A suite of user-friendly global climate models: Hysteresis experiments  

NASA Astrophysics Data System (ADS)

A hierarchy of global spectral circulation models is introduced ranging from the shallow-water system via the primitive-equation dynamical core of the atmosphere to the Planet Simulator as a Global Climate Model (GCM) of Intermediate Complexity (MIC) which can be used to run climate and paleo-climate simulations for time scales up to ten thousand years or more in an acceptable real time. The priorities in development are set to speed, easy handling and portability with a modular structure suitable for problem-dependent configuration. Adaptions exist for the planetary atmospheres of Mars and of Saturn's moon Titan and are being extended. Common coupling interfaces enable the addition of ocean, ice, vegetation models and more. An interactive mode with a Model Starter and a Graphical User Interface (GUI) is available to select a configuration from the available model suite, to set its parameters and inspect atmospheric fields while changing the models' parameters on the fly. This is especially useful for teaching, debugging and tuning of parameterizations. An updated overview of the model suite's features is presented based on the Earth-like climate model Planet Simulator with mixed-layer ocean introducing static and memory hysteresis in terms of a parameter sweep of the solar constant and CO2 concentrations. The static hysteresis experiment demonstrates that the solar constant varying by 20% reveals warm and snowball Earth climate regimes depending on the history of the system. This hysteresis subjected to a thermodynamic analysis shows the following features: i) Both climate regimes are characterized by global mean surface temperature and entropy growing with increasing solar constant. ii) The climate system's efficiency decreases (increases) with increasing solar constant in present-day warm (snowball) climate conditions. iii) Climate transitions near bifurcation points are characterized by high efficiency associated with the system's large distance from the stable regime. Memory hysteresis evolves when changing the direct atmospheric radiative forcing which, associated with a well-mixed CO2 concentration, modifies the planetary thermodynamic state, and hence the surface temperature. The hysteresis effected by different CO2 change rates is analysed: i) The response is due to infrared cooling (for constant temperature lapse-rate) which, in turn, is related to the surface temperature through the Stefan-Boltzmann law in a ratio proportional to the new infrared opacity. Subsequent indirect effects, that are water-vapour-greenhouse and ice-albedo feedbacks, enhance the response. ii) Different rates of CO2 variation may lead to similar transient climates characterized by the same global mean surface temperature but different values of CO2 concentration. iii) Far from the bifurcation points, the model's climate depends on the history of the radiative forcing thus displaying a hysteresis cycle that is neither static nor dynamical, but is related to the memory response of the model determined by the mixed-layer depth of the ocean. Results are supported by a zero-dimensional energy balance model.

Fraedrich, K.

2012-05-01

98

Improving DOE-2's RESYS routine: User defined functions to provide more accurate part load energy use and humidity predictions  

SciTech Connect

In hourly energy simulations, it is important to properly predict the performance of air conditioning systems over a range of full and part load operating conditions. An important component of these calculations is to properly consider the performance of the cycling air conditioner and how it interacts with the building. This paper presents improved approaches to properly account for the part load performance of residential and light commercial air conditioning systems in DOE-2. First, more accurate correlations are given to predict the degradation of system efficiency at part load conditions. In addition, a user-defined function for RESYS is developed that provides improved predictions of air conditioner sensible and latent capacity at part load conditions. The user function also provides more accurate predictions of space humidity by adding ''lumped'' moisture capacitance into the calculations. The improved cooling coil model and the addition of moisture capacitance predicts humidity swings that are more representative of the performance observed in real buildings.

Henderson, Hugh I.; Parker, Danny; Huang, Yu J.

2000-08-04

99

User friendly line CAPTCHAs  

Microsoft Academic Search

CAPTCHAs or reverse Turing tests are real-time assessments used by programs (or computers) to tell humans and machines apart. This is achieved by assigning and assessing hard AI problems that could only be solved easily by human but not by machines. Applications of such assessments range from stopping spammers from automatically filling online forms to preventing hackers from performing dictionary

A. K. B. Karunathilake; B. M. D. Balasuriya; R. G. Ragel

2009-01-01

100

Biblio-MetReS for user-friendly mining of genes and biological processes in scientific documents.  

PubMed

One way to initiate the reconstruction of molecular circuits is by using automated text-mining techniques. Developing more efficient methods for such reconstruction is a topic of active research, and those methods are typically included by bioinformaticians in pipelines used to mine and curate large literature datasets. Nevertheless, experimental biologists have a limited number of available user-friendly tools that use text-mining for network reconstruction and require no programming skills to use. One of these tools is Biblio-MetReS. Originally, this tool permitted an on-the-fly analysis of documents contained in a number of web-based literature databases to identify co-occurrence of proteins/genes. This approach ensured results that were always up-to-date with the latest live version of the databases. However, this 'up-to-dateness' came at the cost of large execution times. Here we report an evolution of the application Biblio-MetReS that permits constructing co-occurrence networks for genes, GO processes, Pathways, or any combination of the three types of entities and graphically represent those entities. We show that the performance of Biblio-MetReS in identifying gene co-occurrence is as least as good as that of other comparable applications (STRING and iHOP). In addition, we also show that the identification of GO processes is on par to that reported in the latest BioCreAtIvE challenge. Finally, we also report the implementation of a new strategy that combines on-the-fly analysis of new documents with preprocessed information from documents that were encountered in previous analyses. This combination simultaneously decreases program run time and maintains 'up-to-dateness' of the results. Availability: http://metres.udl.cat/index.php/downloads, Contact: metres.cmb@gmail.com. PMID:24688854

Usie, Anabel; Karathia, Hiren; Teixidó, Ivan; Alves, Rui; Solsona, Francesc

2014-01-01

101

Development of a new, fast, user friendly, ray tracing program "CSIM" for the simulation of parallelhole collimators.  

PubMed

We have developed a fast, user friendly, ray-tracing program, "CSIM" for low-energy gamma rays (up to ?200keV) to simulate the performance characteristics of parallelhole collimators. We have used a ray-tracing approach to find the sensitivity and resolution of the parallelhole collimator by including the penetration of photons through the collimator due to the finite attenuation of the collimator material. "CSIM" can calculate the sensitivity of the collimator, the geometric and penetrating photon ratios, and the 1D and 2D point source response functions (PSF) with the statistical uncertainty for different hole shapes (e.g. square, hexagonal, and cylindrical). We have used "CSIM" to simulate the collimator of the YAP-(S)PETII small animal scanner. We present the analysis of the YAP-(S)PETII scanner round-hole parallel collimator designed for nuclear medicine imaging at 140keV. For this aim, different designs have been considered for a variety of source-collimator distances (b=5, 10, 15, 20cm). Resolution and sensitivity characteristics have been plotted as a function of the collimator thickness and the diameter of the hole. For each value of the source-collimator distance, and for each collimator thickness investigated, the trade-off between sensitivity and spatial resolution has been given as a series of characteristic curves. Then, we compare our simulated resolution and sensitivity results to the analytically calculated ones and found that the analytically calculated results for the YAP-(S)PETII scanner collimator are not far away the results predicted by CSIM and also with the experimentally measured resolution values. PMID:23347780

Erturk, Sakine Sebnem; Del Guerra, Alberto

2013-06-01

102

Prediction of forming limit curves of sheet metals using Hill’s 1993 user-friendly yield criterion of anisotropic materials  

Microsoft Academic Search

A user-friendly yield criterion was proposed by Hill in 1993, which utilizes five independent material parameters in representing the yield locus. In the present investigation, an attempt is made to analyze forming limits in sheet metals based on this yield criterion and the M–K approach. Comparison of the predicted results with experimental data indicates that Hill’s 1993 yield criterion is

Siguang Xu; Klaus J. Weinmann

1998-01-01

103

Towards automatic recommendation of friend lists  

Microsoft Academic Search

Facebook access-control lists, called friend lists, are difficult to create manually. Previous work on automating these lists has used friend details entered by the user. Our approach automates them by merging virtual friend cliques using certain heuristics that determine if two virtual friend cliques correspond to a single actual friend clique. A small user study found that our lists were

Kelli Bacon; Prasun Dewan

2009-01-01

104

CrossSearch, a user-friendly search engine for detecting chemically cross-linked peptides in conjugated proteins.  

PubMed

Chemical cross-linking and high resolution MS have been integrated successfully to capture protein interactions and provide low resolution structural data for proteins that are refractive to analyses by NMR or crystallography. Despite the versatility of these combined techniques, the array of products that is generated from the cross-linking and proteolytic digestion of proteins is immense and generally requires the use of labeling strategies and/or data base search algorithms to distinguish actual cross-linked peptides from the many side products of cross-linking. Most strategies reported to date have focused on the analysis of small cross-linked protein complexes (<60 kDa) because the number of potential forms of covalently modified peptides increases dramatically with the number of peptides generated from the digestion of such complexes. We report herein the development of a user-friendly search engine, CrossSearch, that provides the foundation for an overarching strategy to detect cross-linked peptides from the digests of large (>or=170-kDa) cross-linked proteins, i.e. conjugates. Our strategy combines the use of a low excess of cross-linker, data base searching, and Fourier transform ion cyclotron resonance MS to experimentally minimize and theoretically cull the side products of cross-linking. Using this strategy, the (alpha beta gamma delta)(4) phosphorylase kinase model complex was cross-linked to form with high specificity a 170-kDa betagamma conjugate in which we identified residues involved in the intramolecular cross-linking of the 125-kDa beta subunit between its regulatory N terminus and its C terminus. This finding provides an explanation for previously published homodimeric two-hybrid interactions of the beta subunit and suggests a dynamic structural role for the regulatory N terminus of that subunit. The results offer proof of concept for the CrossSearch strategy for analyzing conjugates and are the first to reveal a tertiary structural element of either homologous alpha or beta regulatory subunit of phosphorylase kinase. PMID:18281724

Nadeau, Owen W; Wyckoff, Gerald J; Paschall, Justin E; Artigues, Antonio; Sage, Jessica; Villar, Maria T; Carlson, Gerald M

2008-04-01

105

A user-friendly application for the extraction of kubios hrv output to an optimal format for statistical analysis - biomed 2011.  

PubMed

The aim of the present manuscript is to present a user-friendly and flexible platform for transforming Kubios HRV output files to an .xls-file format, used by MS Excel. The program utilizes either native or bundled Java and is platform-independent and mobile. This means that it can run without being installed on a computer. It also has an option of continuous transferring of data indicating that it can run in the background while Kubios produces output files. The program checks for changes in the file structure and automatically updates the .xls- output file. PMID:21525593

Johnsen Lind, Andreas; Helge Johnsen, Bjorn; Hill, Labarron K; Sollers Iii, John J; Thayer, Julian F

2011-01-01

106

The Allergic Airway Inflammation Repository - a user-friendly, curated resource of mRNA expression levels in studies of allergic airways.  

PubMed

Public microarray databases allow analysis of expression levels of candidate genes in different contexts. However, finding relevant microarray data is complicated by the large number of available studies. We have compiled a user-friendly, open-access database of mRNA microarray experiments relevant to allergic airway inflammation, the Allergic Airway Inflammation Repository (AAIR, http://aair.cimed.ike.liu.se/). The aim is to allow allergy researchers to determine the expression profile of their genes of interest in multiple clinical data sets and several experimental systems quickly and intuitively. AAIR also provides quick links to other relevant information such as experimental protocols, related literature and raw data files. PMID:24888382

Gawel, D R; Rani James, A; Benson, M; Liljenström, R; Muraro, A; Nestor, C E; Zhang, H; Gustafsson, M

2014-08-01

107

New User-Friendly Approach to Obtain an Eisenberg Plot and Its Use as a Practical Tool in Protein Sequence Analysis  

PubMed Central

The Eisenberg plot or hydrophobic moment plot methodology is one of the most frequently used methods of bioinformatics. Bioinformatics is more and more recognized as a helpful tool in Life Sciences in general, and recent developments in approaches recognizing lipid binding regions in proteins are promising in this respect. In this study a bioinformatics approach specialized in identifying lipid binding helical regions in proteins was used to obtain an Eisenberg plot. The validity of the Heliquest generated hydrophobic moment plot was checked and exemplified. This study indicates that the Eisenberg plot methodology can be transferred to another hydrophobicity scale and renders a user-friendly approach which can be utilized in routine checks in protein–lipid interaction and in protein and peptide lipid binding characterization studies. A combined approach seems to be advantageous and results in a powerful tool in the search of helical lipid-binding regions in proteins and peptides. The strength and limitations of the Eisenberg plot approach itself are discussed as well. The presented approach not only leads to a better understanding of the nature of the protein–lipid interactions but also provides a user-friendly tool for the search of lipid-binding regions in proteins and peptides.

Keller, Rob C.A.

2011-01-01

108

CloudDOE: A User-Friendly Tool for Deploying Hadoop Clouds and Analyzing High-Throughput Sequencing Data with MapReduce  

PubMed Central

Background Explosive growth of next-generation sequencing data has resulted in ultra-large-scale data sets and ensuing computational problems. Cloud computing provides an on-demand and scalable environment for large-scale data analysis. Using a MapReduce framework, data and workload can be distributed via a network to computers in the cloud to substantially reduce computational latency. Hadoop/MapReduce has been successfully adopted in bioinformatics for genome assembly, mapping reads to genomes, and finding single nucleotide polymorphisms. Major cloud providers offer Hadoop cloud services to their users. However, it remains technically challenging to deploy a Hadoop cloud for those who prefer to run MapReduce programs in a cluster without built-in Hadoop/MapReduce. Results We present CloudDOE, a platform-independent software package implemented in Java. CloudDOE encapsulates technical details behind a user-friendly graphical interface, thus liberating scientists from having to perform complicated operational procedures. Users are guided through the user interface to deploy a Hadoop cloud within in-house computing environments and to run applications specifically targeted for bioinformatics, including CloudBurst, CloudBrush, and CloudRS. One may also use CloudDOE on top of a public cloud. CloudDOE consists of three wizards, i.e., Deploy, Operate, and Extend wizards. Deploy wizard is designed to aid the system administrator to deploy a Hadoop cloud. It installs Java runtime environment version 1.6 and Hadoop version 0.20.203, and initiates the service automatically. Operate wizard allows the user to run a MapReduce application on the dashboard list. To extend the dashboard list, the administrator may install a new MapReduce application using Extend wizard. Conclusions CloudDOE is a user-friendly tool for deploying a Hadoop cloud. Its smart wizards substantially reduce the complexity and costs of deployment, execution, enhancement, and management. Interested users may collaborate to improve the source code of CloudDOE to further incorporate more MapReduce bioinformatics tools into CloudDOE and support next-generation big data open source tools, e.g., Hadoop BigTop and Spark. Availability: CloudDOE is distributed under Apache License 2.0 and is freely available at http://clouddoe.iis.sinica.edu.tw/.

Chung, Wei-Chun; Chen, Chien-Chih; Ho, Jan-Ming; Lin, Chung-Yen; Hsu, Wen-Lian; Wang, Yu-Chun; Lee, D. T.; Lai, Feipei; Huang, Chih-Wei; Chang, Yu-Jung

2014-01-01

109

Inleiding in Het TUBA-Systeem (Introduction to the Tools for User-Friendly Business Applications (TUBA) System).  

National Technical Information Service (NTIS)

A system which provides automated aids to enable the user (systems designers and programmers) to realize the desired data processing in a simple way is described. It is a generator of administrative applications. The modular structure of the application p...

F. A. Vanhoeve R. Engmann

1985-01-01

110

A user-friendly Matlab program and GUI for the pseudorotation analysis of saturated five-membered ring systems based on scalar coupling constants  

PubMed Central

Background The advent of combinatorial chemistry has revived the interest in five-membered heterocyclic rings as scaffolds in pharmaceutical research. They are also the target of modifications in nucleic acid chemistry. Hence, the characterization of their conformational features is of considerable interest. This can be accomplished from the analysis of the 3JHH scalar coupling constants. Results A freely available program including an easy-to-use graphical user interface (GUI) has been developed for the calculation of five-membered ring conformations from scalar coupling constant data. A variety of operational modes and parameterizations can be selected by the user, and the coupling constants and electronegativity parameters can be defined interactively. Furthermore, the possibility of generating high-quality graphical output of the conformational space accessible to the molecule under study facilitates the interpretation of the results. These features are illustrated via the conformational analysis of two 4'-thio-2'-deoxynucleoside analogs. Results are discussed and compared with those obtained using the original PSEUROT program. Conclusion A user-friendly Matlab interface has been developed and tested. This should considerably improve the accessibility of this kind of calculations to the chemical community.

Hendrickx, Pieter MS; Martins, Jose C

2008-01-01

111

SpectraClassifier 1.0: a user friendly, automated MRS-based classifier-development system  

Microsoft Academic Search

BACKGROUND: SpectraClassifier (SC) is a Java solution for designing and implementing Magnetic Resonance Spectroscopy (MRS)-based classifiers. The main goal of SC is to allow users with minimum background knowledge of multivariate statistics to perform a fully automated pattern recognition analysis. SC incorporates feature selection (greedy stepwise approach, either forward or backward), and feature extraction (PCA). Fisher Linear Discriminant Analysis is

Sandra Ortega-Martorell; Ivįn Olier; Margarida Julią-Sapé; Carles Arśs

2010-01-01

112

EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data  

Microsoft Academic Search

The EpiGRAPH web service http:\\/\\/epigraph.mpi-inf.mpg.de\\/ enables biologists to uncover hidden associations in vertebrate genome and epigenome datasets. Users can upload sets of genomic regions and EpiGRAPH will test multiple attributes (including DNA sequence, chromatin structure, epigenetic modifications and evolutionary conservation) for enrichment or depletion among these regions. Furthermore, EpiGRAPH learns to predictively identify similar genomic regions. This paper demonstrates EpiGRAPH's

Christoph Bock; Konstantin Halachev; Joachim Büch; Thomas Lengauer

2009-01-01

113

A proposal for a user-friendly modular framework for the simulation of x-ray experiments  

NASA Astrophysics Data System (ADS)

As experimental concept and execution become increasingly complex across the spectrum of user-driven light sources, data analysis becomes more complicated and the urgency of completing an experiment on the first attempt grows. It has become apparent that simulation of the expected signal from such experiments can increase the likelihood of success of a particular experiment and the efficiency of a facility as a whole. Here, we propose a modular approach to the simulation problem, which will build on existing expertise and software. Additionally, we are working to support the simulation of partially coherent fields where the photon degeneracy parameter is much larger than unity.

Williams, G. J.; Boehnlein, A.; Graf, N.; Koi, T.; Xiao, S.

2014-03-01

114

EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data  

PubMed Central

The EpiGRAPH web service enables biologists to uncover hidden associations in vertebrate genome and epigenome datasets. Users can upload sets of genomic regions and EpiGRAPH will test multiple attributes (including DNA sequence, chromatin structure, epigenetic modifications and evolutionary conservation) for enrichment or depletion among these regions. Furthermore, EpiGRAPH learns to predictively identify similar genomic regions. This paper demonstrates EpiGRAPH's practical utility in a case study on monoallelic gene expression and describes its novel approach to reproducible bioinformatic analysis.

Bock, Christoph; Halachev, Konstantin; Buch, Joachim; Lengauer, Thomas

2009-01-01

115

User-friendly solutions for microarray quality control and pre-processing on ArrayAnalysis.org.  

PubMed

Quality control (QC) is crucial for any scientific method producing data. Applying adequate QC introduces new challenges in the genomics field where large amounts of data are produced with complex technologies. For DNA microarrays, specific algorithms for QC and pre-processing including normalization have been developed by the scientific community, especially for expression chips of the Affymetrix platform. Many of these have been implemented in the statistical scripting language R and are available from the Bioconductor repository. However, application is hampered by lack of integrative tools that can be used by users of any experience level. To fill this gap, we developed a freely available tool for QC and pre-processing of Affymetrix gene expression results, extending, integrating and harmonizing functionality of Bioconductor packages. The tool can be easily accessed through a wizard-like web portal at http://www.arrayanalysis.org or downloaded for local use in R. The portal provides extensive documentation, including user guides, interpretation help with real output illustrations and detailed technical documentation. It assists newcomers to the field in performing state-of-the-art QC and pre-processing while offering data analysts an integral open-source package. Providing the scientific community with this easily accessible tool will allow improving data quality and reuse and adoption of standards. PMID:23620278

Eijssen, Lars M T; Jaillard, Magali; Adriaens, Michiel E; Gaj, Stan; de Groot, Philip J; Müller, Michael; Evelo, Chris T

2013-07-01

116

Mapping health in the Great Lakes areas of concern: a user-friendly tool for policy and decision makers.  

PubMed Central

The role of the physical environment as a determinant of health is a major concern reported by the general public as well as by many policymakers. However, it remains one of the health determinants for which few available measures or indicators are readily available. This lack of data is compounded by the fact that evidence for direct cause-and-effect relationships in the literature is often equivocal, leading to feelings of uncertainty among the lay public and often leading to indecision among policymakers. In this article we examine one aspect of the physical environment--water pollution in the Great Lakes Areas of Concern (AOCs)--and its potential impacts on a wide range of (plausible) human health outcomes. Essentially, the International Joint Commission, the international agency that oversees Great Lakes water quality and related issues, worked with Health Canada to produce a report for each of the 17 AOCs on the Canadian side of the Great Lakes, outlining a long list of health outcomes and the potential relationships these might have with environmental exposures known or suspected to exist in the Great Lakes basin. These reports are based solely on secondary health data and a thorough review of the environmental epidemiologic literature. The use of these reports by local health policymakers as well as by public health officials in the AOCs was limited, however, by the presentation of vast amounts of data in a series of tables with various outcome measures. The reports were therefore not used widely by the audience for whom they were intended. In this paper we report the results of an undertaking designed to reduce the data and present them in a more policy-friendly manner, using a geographic information system. We do not attempt to answer directly questions related to cause and effect vis-ą-vis the relationships between environment and health in the Great Lakes; rather, this work is a hypothesis-generating exercise that will help sharpen the focus of research into this increasingly important area of public health concern.

Elliott, S J; Eyles, J; DeLuca, P

2001-01-01

117

DietPLUS- a User-friendly '2 in 1' Food Composition Database and Calculator of Nutrient Intakes.  

PubMed

The teaching and research tool called 'DietPLUS', developed by the present author at an institution of higher learning in 2007, contains nutrient information of 840 food items in Excel format. DietPLUS functions as a '2-in-1' food composition database plus a rapid calculator of nutrient intakes, with the option of 'collapsing' the food composition face leaving only the nutrient calculator face. The macronutrients featured in the programme are energy, protein, fat, carbohydrates, dietary fibre, sugars (intrinsic + added), polyunsatuared omega-6 fatty acids (mainly linoleic acid, LA) and polyunsaturated omega-3 fatty acids [alphalinolenic acid (ALA) or eicosapentaenic acid (EPA) + docosahexaenolic acid (DHA)]. The micronutrients in the programme are vitamin A (as retinol equivalents, RE), vitamin C, thiamin (vitamin B1), riboflavin (vitamin B2), and niacin. Cholesterol content was included to complete the list of food components tabled. Food items consumed are converted into gram quantities (edible portion) and are entered in one column in the Excel programme which emphasises the simplicity and user-friendliness of the present nutrient calculator. DietPLUS instantaneously sums up the macronutrients and micronutrients consumed with each subsequent entry. Macronutrients (protein, fat, carbohydrate, sugars and dietary fibre) consumed are presented as gram quantities and a percentage of the Recommended Nutrient Intakes for Malaysia 2005. An approximate number of servings are also provided for vegetables, fruits, legumes, fish and meat, which may be useful in meal planning and nutrition/dietetic counselling. PMID:22691859

Tony Ng, K W

2010-04-01

118

CO2calc: A User-Friendly Seawater Carbon Calculator for Windows, Mac OS X, and iOS (iPhone)  

USGS Publications Warehouse

A user-friendly, stand-alone application for the calculation of carbonate system parameters was developed by the U.S. Geological Survey Florida Shelf Ecosystems Response to Climate Change Project in response to its Ocean Acidification Task. The application, by Mark Hansen and Lisa Robbins, USGS St. Petersburg, FL, Joanie Kleypas, NCAR, Boulder, CO, and Stephan Meylan, Jacobs Technology, St. Petersburg, FL, is intended as a follow-on to CO2SYS, originally developed by Lewis and Wallace (1998) and later modified for Microsoft Excel? by Denis Pierrot (Pierrot and others, 2006). Besides eliminating the need for using Microsoft Excel on the host system, CO2calc offers several improvements on CO2SYS, including: An improved graphical user interface for data entry and results Additional calculations of air-sea CO2 fluxes (for surface water calculations) The ability to tag data with sample name, comments, date, time, and latitude/longitude The ability to use the system time and date and latitude/ longitude (automatic retrieval of latitude and longitude available on iPhone? 3, 3GS, 4, and Windows? hosts with an attached National Marine Electronics Association (NMEA)-enabled GPS) The ability to process multiple files in a batch processing mode An option to save sample information, data input, and calculated results as a comma-separated value (CSV) file for use with Microsoft Excel, ArcGIS,? or other applications An option to export points with geographic coordinates as a KMZ file for viewing and editing in Google EarthTM

Robbins, L.L.; Hansen, M.E.; Kleypas, J.A.; Meylan, S.C.

2010-01-01

119

FriendSensing: recommending friends using mobile phones  

Microsoft Academic Search

Social-networking sites, such as Facebook, require members to manually find and confirm their friends. Finding friends is tedious for some and may be made less so by automating the process. We propose to do so by means of a framework that we call FriendSensing. Using short-range technologies (e.g., Bluetooth) on their mobile phones, social-networking users \\

Daniele Quercia; Licia Capra

2009-01-01

120

A User-Friendly Forecast.  

ERIC Educational Resources Information Center

The use of the Accu-Weather database system in a junior high school classroom is described. Costs, equipment, and information received are discussed. Two software packages designed for use with meteorological data and Accu-Weather are highlighted. Availability information and a description of the services provided are included. (CW)

Knorr, Thomas, Sr.; Levin, James

1990-01-01

121

The User-Friendly Fallacy.  

ERIC Educational Resources Information Center

Claims that computer programs are needed that operate on commonly available microcomputers and provide guidance in the generation and interrogation of a writer's ideas. Discusses Hugh Burns' program "TOPOI" as an example. Describes ways in which a computer and operator can interact. Criticizes those who view open-response software merely by citing…

Kemp, Fred

1987-01-01

122

Validation of user- and environmentally friendly extraction and clean-up methods for compound-specific stable carbon isotope analysis of organochlorine pesticides and their metabolites in soils.  

PubMed

In order to evaluate the potential of compound-specific stable carbon isotope analysis (CSIA) for tracking organochlorine pesticides in soil systems, sample pre-treatment methods have to be developed, which can provide recoveries sufficient for low detection limits without altering the isotope ratio of the target compounds. In this study we tested the compatibility of CSIA with user- and environmentally friendly extraction methods, including the Quick, Easy, Cheap, Effective, Rugged and Safe procedure (QuEChERS), Ultrasonic Assisted Extraction (USE) and Focused Ultrasonic Extraction (FUSE), as well as clean-up methods, including sulfuric acid clean-up and Florisil(®) column chromatography for hexachlorocyclohexanes (HCHs), p,p'-dichlorodiphenyltrichloroethane (DDT) and their environmental metabolites (chlorinated benzenes, dichlorodiphenyldichloroethylene - DDE and dichlorodiphenyldichloroethane - DDD) in soils. We optimized the extraction methods for maximum recovery and pre-concentration. At optimal conditions, all extraction methods and clean-up procedures, as well as the pre-concentration of the extract by solvent evaporation, led to insignificant changes in carbon isotope ratios of the target compounds. We modified the USE procedure to increase the volume of withdrawn organic extract, resulting in a higher pre-concentration of the target compounds by the subsequent solvent evaporation step. This Modified Ultrasonic Assisted Extraction (MUSE) was the most suitable procedure, and it was validated for the determination of carbon isotope ratios of the target compounds using two different types of soil matrices. The method could be applied to analyze carbon isotope ratios of HCHs, DDT, and their chlorinated metabolites in soil samples with concentrations ranging from 0.3 to 0.8mg/kg. The analytical uncertainty of MUSE, incorporating both accuracy and precision, was ?0.4‰. PMID:24980091

Ivdra, Natalija; Herrero-Martķn, Sara; Fischer, Anko

2014-08-15

123

Siberian Earth System Science Cluster - A web-based Geoportal to provide user-friendly Earth Observation Products for supporting NEESPI scientists  

NASA Astrophysics Data System (ADS)

To provide earth observation products in the area of Siberia, the Siberian Earth System Science Cluster (SIB-ESS-C) was established as a spatial data infrastructure at the University of Jena (Germany), Department for Earth Observation. This spatial data infrastructure implements standards published by the Open Geospatial Consortium (OGC) and the International Organizsation for Standardization (ISO) for data discovery, data access, data processing and data analysis. The objective of SIB-ESS-C is to faciliate environmental research and Earth system science in Siberia. The region for this project covers the entire Asian part of the Russian Federation approximately between 58°E - 170°W and 48°N - 80°N. To provide discovery, access and analysis services a webportal was published for searching and visualisation of available data. This webportal is based on current web technologies like AJAX, Drupal Content Management System as backend software and a user-friendly surface with Drag-n-Drop and further mouse events. To have a wide range of regular updated earth observation products, some products from sensor MODIS at the satellites Aqua and Terra were processed. A direct connection to NASA archive servers makes it possible to download MODIS Level 3 and 4 products and integrate it in the SIB-ESS-C infrastructure. These data can be downloaded in a file format called Hierarchical Data Format (HDF). For visualisation and further analysis, this data is reprojected, converted to GeoTIFF and global products clipped to the project area. All these steps are implemented as an automatic process chain. If new MODIS data is available within the infrastructure this process chain is executed. With the link to a MODIS catalogue system, the system gets new data daily. With the implemented analysis processes, timeseries data can be analysed, for example to plot a trend or different time series against one another. Scientists working in this area and working with MODIS data can make use of this service over the webportal. Both searching manually the NASA archive for MODIS data, processing these data automatically and then download it for further processing and using the regular updated products.

Eberle, J.; Gerlach, R.; Hese, S.; Schmullius, C.

2012-04-01

124

Friend Finder  

MedlinePLUS

Friend Finder (Game) Email Embed Grab this Game : friends’: public and private spheres  

Microsoft Academic Search

Friendship is highly significant during the university years. Facebook, widely used by students, is designed to facilitate communication with different groups of ‘friends’. This exploratory study involved interviewing a sample of student users of Facebook: it focuses on the extent to which older adults, especially parents, are accepted as Facebook friends, and the attitudes towards such friendships and potential friendships

Anne West; Jane Lewis; Peter Currie

2009-01-01

131

Towards Friendly Concept-Learners  

Microsoft Academic Search

We give a general overview of CUNT, a user- friendly interactive concept-learner, which can be used as a module for Learning Apprentice Sys­ tems. CLINT combines several interesting fea­ tures : it uses domain-knowledge, generates examples, copes with indirect relevance, shifts its bias, recovers from errors and identifies con­ cepts in the limit.

Luc De Raedt; Maurice Bruynooghe

1989-01-01

132

The Development of a PdCr Integral Weldable Strain Measurement System Based on NASA Lewis PdCr/Pt Strain Sensor for User-Friendly Elevated Temperature Strain Measurements  

NASA Technical Reports Server (NTRS)

This report describes the development of a user friendly weldable strain gage employing the NASA Lewis PdCr/Pt wire strain sensor. The NASA sensors are pre-attached to Hastelloy X or Titanium alloy shims using name spray techniques developed under previous NASA programs. The weldable sensors are then pre-stabilized for 50 hours at 780 C in air. A weldable terminal and high temperature cable is then connected to the sensor and the assembly is pre-calibrated over the full test temperature range. Calibrated resistors are inserted into a bridge completion module at the cool end of the cable to condition the sensor in half or full bridge configuration. The sensor is attached to the structure using a common capacitive discharge spot welder. No additional high temperature stabilization or calibration is required. The resultant device is a pre-calibrated strain transducer which can be plugged into any common variety strain instrumentation.

Wnuk, S. P., Jr.; Wnuk, V. P.

1997-01-01

133

A user-friendly, menu-driven, language-free laser characteristics curves graphing program for desk-top IBM PC compatible computers  

NASA Technical Reports Server (NTRS)

A facility was established that uses collected data and feeds it into mathematical models that generate improved data arrays by correcting for various losses, base line drift, and conversion to unity scaling. These developed data arrays have headers and other identifying information affixed and are subsequently stored in a Laser Materials and Characteristics data base which is accessible to various users. The two part data base: absorption - emission spectra and tabulated data, is developed around twelve laser models. The tabulated section of the data base is divided into several parts: crystalline, optical, mechanical, and thermal properties; aborption and emission spectra information; chemical name and formulas; and miscellaneous. A menu-driven, language-free graphing program will reduce and/or remove the requirement that users become competent FORTRAN programmers and the concomitant requirement that they also spend several days to a few weeks becoming conversant with the GEOGRAF library and sequence of calls and the continual refreshers of both. The work included becoming thoroughly conversant with or at least very familiar with GEOGRAF by GEOCOMP Corp. The development of the graphing program involved trial runs of the various callable library routines on dummy data in order to become familiar with actual implementation and sequencing. This was followed by trial runs with actual data base files and some additional data from current research that was not in the data base but currently needed graphs. After successful runs, with dummy and real data, using actual FORTRAN instructions steps were undertaken to develop the menu-driven language-free implementation of a program which would require the user only know how to use microcomputers. The user would simply be responding to items displayed on the video screen. To assist the user in arriving at the optimum values needed for a specific graph, a paper, and pencil check list was made available to use on the trial runs.

Klutz, Glenn

1989-01-01

134

Dynamo: a flexible, user-friendly development tool for subtomogram averaging of cryo-EM data in high-performance computing environments.  

PubMed

Dynamo is a new software package for subtomogram averaging of cryo Electron Tomography (cryo-ET) data with three main goals: first, Dynamo allows user-transparent adaptation to a variety of high-performance computing platforms such as GPUs or CPU clusters. Second, Dynamo implements user-friendliness through GUI interfaces and scripting resources. Third, Dynamo offers user-flexibility through a plugin API. Besides the alignment and averaging procedures, Dynamo includes native tools for visualization and analysis of results and data, as well as support for third party visualization software, such as Chimera UCSF or EMAN2. As a demonstration of these functionalities, we studied bacterial flagellar motors and showed automatically detected classes with absent and present C-rings. Subtomogram averaging is a common task in current cryo-ET pipelines, which requires extensive computational resources and follows a well-established workflow. However, due to the data diversity, many existing packages offer slight variations of the same algorithm to improve results. One of the main purposes behind Dynamo is to provide explicit tools to allow the user the insertion of custom designed procedures - or plugins - to replace or complement the native algorithms in the different steps of the processing pipeline for subtomogram averaging without the burden of handling parallelization. Custom scripts that implement new approaches devised by the user are integrated into the Dynamo data management system, so that they can be controlled by the GUI or the scripting capacities. Dynamo executables do not require licenses for third party commercial software. Sources, executables and documentation are freely distributed on http://www.dynamo-em.org. PMID:22245546

Castańo-Dķez, Daniel; Kudryashev, Mikhail; Arheit, Marcel; Stahlberg, Henning

2012-05-01

135

Design and implementation of a secure and user-friendly broker platform supporting the end-to-end provisioning of e-homecare services.  

PubMed

We designed a broker platform for e-homecare services using web service technology. The broker allows efficient data communication and guarantees quality requirements such as security, availability and cost-efficiency by dynamic selection of services, minimizing user interactions and simplifying authentication through a single user sign-on. A prototype was implemented, with several e-homecare services (alarm, telemonitoring, audio diary and video-chat). It was evaluated by patients with diabetes and multiple sclerosis. The patients found that the start-up time and overhead imposed by the platform was satisfactory. Having all e-homecare services integrated into a single application, which required only one login, resulted in a high quality of experience for the patients. PMID:20086267

Van Hoecke, Sofie; Steurbaut, Kristof; Taveirne, Kristof; De Turck, Filip; Dhoedt, Bart

2010-01-01

136

An automated HAXPES measurement system with user-friendly GUI for R4000-10 keV at BL46XU in SPring-8  

NASA Astrophysics Data System (ADS)

We have developed a noble HAXPES measurement system, where the controls for sample manipulation and VG Scienta R4000 work together. The main part of the system is developed by spec. R4000 is controlled by sending commands from spec to the TCP server programed by LabVIEW with SESWrapper library. The command line interface of spec is wrapped by a graphical user interface (GUI) which can be easily operated by users. The sample can be aligned in the intuitive way by clicking the position to be measured on the sample image. Fine alignment can be done by scanning the sample position to maximize the count rate of photoelectrons. After setting measurement positions and conditions on the GUI, the automatic measurements through the multiple measurement positions can be performed in this system.

Oji, H.; Matsumoto, T.; Cui, Y.-T.; Son, J.-Y.

2014-04-01

137

Franklin: User Experiences  

SciTech Connect

The newest workhorse of the National Energy Research Scientific Computing Center is a Cray XT4 with 9,736 dual core nodes. This paper summarizes Franklin user experiences from friendly early user period to production period. Selected successful user stories along with top issues affecting user experiences are presented.

National Energy Research Supercomputing Center; He, Yun (Helen); Kramer, William T.C.; Carter, Jonathan; Cardo, Nicholas

2008-05-07

138

Make new friends, but keep the old: recommending people on social networking sites  

Microsoft Academic Search

This paper studies people recommendations designed to help users find known, offline contacts and discover new friends on social networking sites. We evaluated four recommender algorithms in an enterprise social networking site using a personalized survey of 500 users and a field study of 3,000 users. We found all algorithms effective in expanding users' friend lists. Algorithms based on social

Jilin Chen; Werner Geyer; Casey Dugan; Michael J. Muller; Ido Guy

2009-01-01

139

Helping Friends and Family  

MedlinePLUS

... chapter Join our online community Helping Friends and Family Part of living well with Alzheimerā??s is adjusting to your ā??new normalā?¯ and helping family and friends do the same. Knowing what to ...

140

Microwave Fun: User-Friendly Recipe Cards.  

ERIC Educational Resources Information Center

This article explains how a 12-year-old boy with profound mental retardation and autistic behaviors, living in a group home, was taught to follow number- and color-coded directions so that he could independently cook his own meals in a microwave oven. The article covers materials used, the skills taught, adaptations for classroom use, and safety…

Bergstrom, Tom; And Others

1995-01-01

141

User-friendly Indices for Bridge Management  

Microsoft Academic Search

The Road Bureau of the Ministry of Land, Infrastructure and Transport (MLIT) is promoting scientific bridge management to effectively preserve the enormous number of bridges in Japan. In the process of strategic bridge management, it is important to explain the needs for preventive investment or management level of highway bridges using proper indices. The National Institute for Land and Infrastructure

Takashi Tamakoshi; Keita Nakasu; Ryoichi Watanabe

142

Designing user friendly Situational Awareness products  

Microsoft Academic Search

Situational Awareness (SA), Electronic Order of Battle (EOB), and Common Operating Picture (COP) are all terms used to describe getting real-time tactical information into the hands of the warfighter. This information has to be part of a complete on-going process which includes premission planning and in-transit updates via an effective military communications network. This is especially critical in the modem

D. Dusseau; J. A. Negro; B. Clinton

2001-01-01

143

Friends' Discovery Camp  

ERIC Educational Resources Information Center

This article features Friends' Discovery Camp, a program that allows children with and without autism spectrum disorder to learn and play together. In Friends' Discovery Camp, campers take part in sensory-rich experiences, ranging from hands-on activities and performing arts to science experiments and stories teaching social skills. Now in its 7th…

Seymour, Seth

2008-01-01

144

New grower-friendly methods for plant pathogen monitoring.  

PubMed

Accurate plant disease diagnoses and rapid detection and identification of plant pathogens are of utmost importance for controlling plant diseases and mitigating the economic losses they incur. Technological advances have increasingly simplified the tools available for the identification of pathogens to the extent that, in some cases, this can be done directly by growers and producers themselves. Commercially available immunoprinting kits and lateral flow devices (LFDs) for detection of selected plant pathogens are among the first tools of what can be considered grower-friendly pathogen monitoring methods. Research efforts, spurned on by point-of-care needs in the medical field, are paving the way for the further development of on-the-spot diagnostics and multiplex technologies in plant pathology. Grower-friendly methods need to be practical, robust, readily available, and cost-effective. Such methods are not restricted to on-the-spot testing but extend to laboratory services, which are sometimes more practicable for growers, extension agents, regulators, and other users of diagnostic tests. PMID:22607454

De Boer, Solke H; López, Marķa M

2012-01-01

145

Cognition friendly interaction  

NASA Astrophysics Data System (ADS)

This paper identifies yet another field of research, the discipline of human computer interaction, where the concept of 1/f noise can play a vital role. It is argued that friendly interactions between cognition and computation must have a memory and be antipersistent. A mathematical model of such interactions is obtained. The question is then raised as how to build a friendly software, and a possible evolutionary process is indicated. .

Das, Balaram

2000-03-01

146

Introducing GAMER: A Fast and Accurate Method for Ray-tracing Galaxies Using Procedural Noise  

NASA Astrophysics Data System (ADS)

We developed a novel approach for fast and accurate ray-tracing of galaxies using procedural noise fields. Our method allows for efficient and realistic rendering of synthetic galaxy morphologies, where individual components such as the bulge, disk, stars, and dust can be synthesized in different wavelengths. These components follow empirically motivated overall intensity profiles but contain an additional procedural noise component that gives rise to complex natural patterns that mimic interstellar dust and star-forming regions. These patterns produce more realistic-looking galaxy images than using analytical expressions alone. The method is fully parallelized and creates accurate high- and low- resolution images that can be used, for example, in codes simulating strong and weak gravitational lensing. In addition to having a user-friendly graphical user interface, the C++ software package GAMER is easy to implement into an existing code.

Groeneboom, N. E.; Dahle, H.

2014-03-01

147

An Emacs User Interface for Ale  

Microsoft Academic Search

This paper describes a user interface and a set of tools for the Attribute Logic Engine (ALE, Carpenter & Penn 1994) and its implementation in Emacs and dis- cusses some issues related to user interfaces and Grammar Development Environ- ments (GDE). We pay particular attention to user-friendli ness, robustness, reusability and extendability. This user interface uses extensively the flexibility and

Olivier Laurens

1995-01-01

148

A Friend for Kenny  

ERIC Educational Resources Information Center

When I first met Kenny, he was a bright, enthusiastic second grader with a charming smile, quick wit, and artistic bent. Over the course of the next two years, however, nearly everything changed. Homework wasn't turned in. Grades declined. Kenny became argumentative with adults and isolated from classmates he once considered friends. Even his…

Carlson, Beth

2004-01-01

149

Nonverbal Communication in "Friends"  

ERIC Educational Resources Information Center

This activity uses video clips from a popular sitcom, "Friends," to help students grasp the relational, rule-governed, and culture-specific nature of nonverbal communication. It opens students' eyes to nonverbal behaviors that are happening on a daily basis so that they not only master the knowledge but are able to apply it. While other popular…

Chang, Yanrong

2006-01-01

150

Friendly Biometric Credentials.  

National Technical Information Service (NTIS)

26 Mar 2010, the IPMSCG established a Quick Look Team (QLT) to identify ways DoD could enhance friendly-force identity management (IdM) capabilities with biometrics. IdM issues spans business, warfighter and defense intelligence mission areas. Each commun...

2011-01-01

151

Recommend to a Friend?  

ERIC Educational Resources Information Center

New York's Cornell University spends millions of dollars and thousands of staff and volunteer hours to produce more than 1,400 events around the world each year. That's one event every six hours. Is it worth it? Do the 40,000 alumni, parents, and friends who attend feel closer to Cornell after these events? Do they disengage because Cornell didn't…

Cunningham, Jennifer Lynham

2012-01-01

152

Cyber Friendly Fire.  

National Technical Information Service (NTIS)

Cyber friendly fire (FF) is a new concept that has been brought to the attention of Department of Defense (DoD) stakeholders through two workshops that were planned and conducted by the Air Force Research Laboratory (AFRL) and research conducted for AFRL ...

A. D. Roberts F. L. Greitzer T. E. Carroll

2011-01-01

153

Environmentally Friendly Precision Machining  

Microsoft Academic Search

Material removal processing has been investigated both theoretically and experimentally to a certain extent. The demands for environmentally friendly processes impose new parameters such as the use of minimal quantity or even the complete omission of cutting fluids. Therefore, the related processes need to be newly studied in order to be optimized for specific cutting conditions. Cutting fluids are used

J. Kundrįk; A. G. Mamalis; K. Gyįni; A. Markopoulos

2006-01-01

154

Letter from the Friends Chairman  

MedlinePLUS

... Tom Harkin of Iowa (left) and FNLM Chairman Paul Rogers converse at a recent Friends function at ... can write us at the address below. Sincerely, Paul G. Rogers Chairman Friends of the National Library ...

155

Accurate Monitor 1.2  

NSDL National Science Digital Library

With many computer users developing their own Web sites, some of them may be interested in monitoring how search engines may be ranking their site. This latest edition of Accurate Monitor may prove useful, as it allows individuals to find the position of their Web site in search engines like Altavista and Google. Additionally, Accurate Monitor can generate advanced statistics and monitor plugins, along with providing a flexible interface system. This version of Accurate Monitor is compatible with all systems running Windows 95 and higher.

2003-01-01

156

Environmental friendly nitrogen fertilization  

Microsoft Academic Search

With the huge intensification of agriculture and the increasing awareness to human health and natural resources sustainability,\\u000a there was a shift towards the development of environmental friendly N application approaches that support sustainable use\\u000a of land and sustain food production.\\u000a \\u000a \\u000a The effectiveness of such approaches depends on their ability to synchronize plant nitrogen demand with its supply and the\\u000a ability

Avi Shaviv

2005-01-01

157

Environmentally friendly polysilane photoresists  

SciTech Connect

Several novel polysilanes synthesized by the free-radical hydrosilation of oligomeric polyphenylsilane or poly(p-tert- butylphenylsilane) were examined for lithographic behavior. This recently developed route into substituted polysilanes has allowed for the rational design of a variety of polysilanes with a typical chemical properties such as alcohol and aqueous base solubility. Many of the polysilane resists made could be developed in aqueous sodium carbonate and bicarbonate solutions. These materials represent environmentally friendly polysilane resists in both their synthesis and processing.

Beach, J.V.; Loy, D.A. [Sandia National Labs., Albuquerque, NM (United States); Hsiao, Yu-Ling; Waymouth, R.M. [Stanford Univ., CA (United States). Dept. of Chemistry

1995-12-31

158

Dementia-friendly neighbourhoods.  

PubMed

Six research projects that will improve understanding of dementia are to receive £20 million in funding from the UK government. The projects, which will be overseen by the National Institute for Health Research and the Economic and Social Research Council, include investigations into creating dementia-friendly neighbourhoods; the lifestyle changes that can reduce the risk of developing the condition; training care home staff to support patients who become agitated; improving predictions of the future financial costs of dementia; living well with the condition; and the effects of visual aids on wellbeing and quality of life. PMID:24576246

Duffin, Christian

2014-03-01

159

Network-Friendly Gossiping  

NASA Astrophysics Data System (ADS)

The emergence of large-scale distributed applications based on many-to-many communication models, e.g., broadcast and decentralized group communication, has an important impact on the underlying layers, notably the Internet routing infrastructure. To make an effective use of network resources, protocols should both limit the stress (amount of messages) on each infrastructure entity like routers and links, and balance as much as possible the load in the network. Most protocols use application-level metrics such as delays to improve efficiency of content dissemination or routing, but the extend to which such application-centric optimizations help reduce and balance the load imposed to the infrastructure is unclear. In this paper, we elaborate on the design of such network-friendly protocols and associated metrics. More specifically, we investigate random-based gossip dissemination. We propose and evaluate different ways of making this representative protocol network-friendly while keeping its desirable properties (robustness and low delays). Simulations of the proposed methods using synthetic and real network topologies convey and compare their abilities to reduce and balance the load while keeping good performance.

Serbu, Sabina; Rivičre, Étienne; Felber, Pascal

160

AISAIC: a software suite for accurate identification of significant aberrations in cancers.  

PubMed

Accurate identification of significant aberrations in cancers (AISAIC) is a systematic effort to discover potential cancer-driving genes such as oncogenes and tumor suppressors. Two major confounding factors against this goal are the normal cell contamination and random background aberrations in tumor samples. We describe a Java AISAIC package that provides comprehensive analytic functions and graphic user interface for integrating two statistically principled in silico approaches to address the aforementioned challenges in DNA copy number analyses. In addition, the package provides a command-line interface for users with scripting and programming needs to incorporate or extend AISAIC to their customized analysis pipelines. This open-source multiplatform software offers several attractive features: (i) it implements a user friendly complete pipeline from processing raw data to reporting analytic results; (ii) it detects deletion types directly from copy number signals using a Bayes hypothesis test; (iii) it estimates the fraction of normal contamination for each sample; (iv) it produces unbiased null distribution of random background alterations by iterative aberration-exclusive permutations; and (v) it identifies significant consensus regions and the percentage of homozygous/hemizygous deletions across multiple samples. AISAIC also provides users with a parallel computing option to leverage ubiquitous multicore machines. Availability and implementation:?AISAIC is available as a Java application, with a user's guide and source code, at https://code.google.com/p/aisaic/. PMID:24292941

Zhang, Bai; Hou, Xuchu; Yuan, Xiguo; Shih, Ie-Ming; Zhang, Zhen; Clarke, Robert; Wang, Roger R; Fu, Yi; Madhavan, Subha; Wang, Yue; Yu, Guoqiang

2014-02-01

161

TIA Software User's Manual  

NASA Technical Reports Server (NTRS)

This user's manual describes the installation and operation of TIA, the Thermal-Imaging acquisition and processing Application, developed by the Nondestructive Evaluation Sciences Branch at NASA Langley Research Center, Hampton, Virginia. TIA is a user friendly graphical interface application for the Macintosh 2 and higher series computers. The software has been developed to interface with the Perceptics/Westinghouse Pixelpipe(TM) and PixelStore(TM) NuBus cards and the GW Instruments MacADIOS(TM) input-output (I/O) card for the Macintosh for imaging thermal data. The software is also capable of performing generic image-processing functions.

Cramer, K. Elliott; Syed, Hazari I.

1995-01-01

162

The Friend of Man  

NSDL National Science Digital Library

There are many ways to understand the anti-slavery movements in the United States during the 19th century, and newspapers are but one of the key primary document types used by historians. Cornell University is fortunate enough to have a near complete run of the "Friend of Man" newspaper, which was published between 1836 and 1842. This very intriguing title allows curious visitors to learn about a group of people in central New York interested in "changing America" during this unique period. The paper documents the "regional interconnectedness of reform" throughout the region, with a focus on cities such as Utica, Rochester, Buffalo, Albany and New York City. Visitors to the site can browse through the various issues at their leisure and they can also perform a full-text search.

2012-04-20

163

Advanced Environment Friendly Nanotechnologies  

NASA Astrophysics Data System (ADS)

The economic, security, military and environmental implications of molecular manufacturing are extreme. Unfortunately, conflicting definitions of nanotechnology and blurry distinctions between significantly different fields have complicated the effort to understand those differences and to develop sensible, effective policy for each. The risks of today's nanoscale technologies cannot be treated the same as the risks of longer-term molecular manufacturing. It is a mistake to put them together in one basket for policy consideration — each is important to address, but they offer different problems and will require far different solutions. As used today, the term nanotechnology usually refers to a broad collection of mostly disconnected fields. Essentially, anything sufficiently small and interesting can be called nanotechnology. Much of it is harmless. For the rest, much of the harm is of familiar and limited quality. Molecular manufacturing, by contrast, will bring unfamiliar risks and new classes of problems. The advanced environment friendly nanotechnologies elaborated by Israel Company Polymate Ltd. — International Research Center are illustrated.

Figovsky, O.; Beilin, D.; Blank, N.

164

LIMS user acceptance testing.  

PubMed

Laboratory Information Management Systems (LIMS) play a key role in the pharmaceutical industry. Thorough and accurate validation of such systems is critical and is a regulatory requirement. LIMS user acceptance testing is one aspect of this testing and enables the user to make a decision to accept or reject implementation of the system. This paper discusses key elements in facilitating the development and execution of a LIMS User Acceptance Test Plan (UATP). PMID:14660299

Klein, Corbett S

2003-01-01

165

Understanding Friendship between Critical Friends  

ERIC Educational Resources Information Center

This conceptual article discusses the issue of friendship implied by the term "critical friends". Our argument relates to the generalized use of the term "friendship" and the assumptions that it may carry compared with the actuality of the roles played by critical friends. We attempt to build a more precise definition of friendship which we…

Gibbs, Paul; Angelides, Panayiotis

2008-01-01

166

BM-Map: an efficient software package for accurately allocating multireads of RNA-sequencing data  

PubMed Central

Background RNA sequencing (RNA-seq) has become a major tool for biomedical research. A key step in analyzing RNA-seq data is to infer the origin of short reads in the source genome, and for this purpose, many read alignment/mapping software programs have been developed. Usually, the majority of mappable reads can be mapped to one unambiguous genomic location, and these reads are called unique reads. However, a considerable proportion of mappable reads can be aligned to more than one genomic location with the same or similar fidelities, and they are called "multireads". Allocating these multireads is challenging but critical for interpreting RNA-seq data. We recently developed a Bayesian stochastic model that allocates multireads more accurately than alternative methods (Ji et al. Biometrics 2011). Results In order to serve a greater biological community, we have implemented this method in a stand-alone, efficient, and user-friendly software package, BM-Map. BM-Map takes SAM (Sequence Alignment/Map), the most popular read alignment format, as the standard input; then based on the Bayesian model, it calculates mapping probabilities of multireads for competing genomic loci; and BM-Map generates the output by adding mapping probabilities to the original SAM file so that users can easily perform downstream analyses. The program is available in three common operating systems, Linux, Mac and PC. Moreover, we have built a dedicated website, http://bioinformatics.mdanderson.org/main/BM-Map, which includes free downloads, detailed tutorials and illustration examples. Conclusions We have developed a stand-alone, efficient, and user-friendly software package for accurately allocating multireads, which is an important addition to our previous methodology paper. We believe that this bioinformatics tool will greatly help RNA-seq and related applications reach their full potential in life science research.

2012-01-01

167

Finding Friends for Red Dwarfs  

NASA Astrophysics Data System (ADS)

Stellar multiplicity provides fundamental clues about the nature of star formation, the distribution of baryonic mass in the Universe, and the evolution of stellar systems over time. How stars are parceled into singles, doubles, and higher order multiples also provides clues about the angular momentum distribution in stellar systems and constraints on whether planets may be found. Because of their large numbers, arguably the best sample that can be studied to understand stellar multiplicity are the nearby M-dwarfs. Companion searches have been done for M-dwarfs during the past few decades, but all of the surveys have had on the order of 100 targets. With samples of this size, our statistical understanding of the distribution of companions is quite weak. We are currently systematically surveying 1200 red dwarfs that have trigonometric parallaxes placing them within 25 pc of the Sun for stellar companions at separations of 1" to 10'. By obtaining I-band images using the CTIO 0.9m in the south and the Lowell 42in in the north, we are probing the environs of these systems for companions at separations of 1" to 3'. Because the systems all have accurate parallaxes, biases inherent to photometrically-selected samples are eliminated. A complementary reconnaissance of wider companions out to 10' is also being done via blinking of SuperCOSMOS BRI images. The results will allow statistical analyses of the nearby M-dwarf population, refinement of the solar neighborhood membership roster, and improvement of the mass function for these objects at the end of the main sequence. This is the largest, most comprehensive study ever done of the multiplicity of the most common stars in the Galaxy, one that will hopefully reveal those hidden friends lurking in the darkness. This work is supported by NSF grant AST 09-08402, the SMARTS Consortium, and Georgia State University.

Winters, Jennifer G.; Henry, T. J.; Boyd, M. R.; Hambly, N. C.; RECONS

2011-01-01

168

Field Friendly Tuberculosis Biosensor  

NASA Astrophysics Data System (ADS)

Tuberculosis (TB) is a fading threat in the United States, but in the developing world it is still a major health-care concern. Given the rising number of cases and lack of resources, there is a desperate need for an affordable, portable detection system. We are working towards the development of a field-friendly immunological biosensor that utilizes florescence microscopy to undertake this task. We observe fluorescently labeled antibodies/antigens as they bind to a glass slide treated with polyethylene glycol (PEG) in order to inhibit non-specific adsorption. Antibodies against the antigens of interest are bound to the PEGylated glass slides via biotin-streptavidin interactions. Then, fluorescently labeled antibodies are mixed with different concentrations of TB antigens and this solution is incubated on the treated glass slides for 30 minutes. The slides are thoroughly rinsed with water following the incubation period. The antigens are then detected by fluorescence using a low-cost biosensor. Our system includes a ``supermarket-scanner'' HeNe laser, home-built electronics, off-the-shelf optics and a Si photodiode. Work is underway to incorporate a flow-cell into the system, in a small portable box.

Proper, N.; Scherman, M. S.; Jevsevar, K. L.; Stone, J.; McNeil, M. R.; Krapf, D.

2009-10-01

169

Friends of science  

NASA Astrophysics Data System (ADS)

Ten members of Congress have been presented with the Friends of Science Award by the National Coalition for Science and Technology (NCST). The awards, honoring significant contributions to science, engineering, and science education, are made every 2 years at the end of the congressional session. The recipients this year are Sen. Pete V. Domenici (R-N.M.), Rep. Joseph D. Early (D-Mass.), Rep. Bill Frenzel (R-Minn.), Rep. Albert Gore, Jr. (D-Tenn.), Rep. Judd Gregg (R-N.H.), Sen. Daniel K. Inouye (D-Hawaii), Rep. Stan Lundine (D-N.Y.), Sen. Sam Nunn (D-Ga.), Rep. Henry Waxman (D-Calif.), and Rep. Ed Zschau (R-Calif).Except for Sen. Inouye, whose term expires in 1986, all of this year's recipients were up for reelection in the national elections held November 6. All were successful in securing another term in Congress. In addition, Albert Gore was successful in his bid for a Senate seat, filling the vacancy left by the retiring Senate Majority Leader Howard H. Baker (R-Tenn.)

170

Accuracy and Bias in Adolescents' Perceptions of Friends' Substance Use  

PubMed Central

This study tested competing hypotheses related to the false consensus effect and pluralistic ignorance by examining the accuracy and bias of adolescents’ perceptions of peer substance use, and the effects of their own substance use, gender, and age on perceptions of peer behavior. Two samples (Ns = 163 and 2,194) that collected data on peer nominations, perceptions of peer substance use, and self-reports of substance use were used in analyses. Results from both samples provided evidence supporting the false consensus effect, that is, adolescents’ reports of their friends’ substance use were biased in the direction of their own use. Users and non-users did not differ in accuracy of perceptions; however, across all substances and samples, they differed significantly in bias. Substance users displayed nearly perfect liberal bias, assuming their friends also used substances. Non-users displayed an opposite, conservative bias, assuming their friends did not use substances. Gender and age differences in bias also were observed, with older adolescents and females having more liberal biases than younger adolescents and males. Results suggest the importance of differentiating the effects of actual and perceived peer substance use.

Henry, David B.; Kobus, Kimberly; Schoeny, Michael E.

2013-01-01

171

User friendly IT Services for Monitoring and Prevention during Pregnancy.  

PubMed

A healthy lifestyle for a mother and monitoring both mother and fetus activities are crucial factors for a normal pregnancy without hazardous conditions. This paper proposes a cloud computing solution and a mobile application which collect data from the sensors to be used in Obstetrics-Gynecology Department. This application monitors the dietary plan of the pregnant and gives her the possibility to socialize and share pregnancy experience with the rest of women from the social network from the hospital. The physicians can access the information's of the patient in real time and they can alert mothers in some situations. Using this cloud computing device, the health condition of the pregnant women may be improved. PMID:25000061

Cri?an-Vida, Mihaela; Serban, Alexandru; Ghihor-Izdr?il?, Ioana; Mirea, Adrian; Stoicu-Tivadar, Lacramioara

2014-01-01

172

User-Friendly Handbook for Mixed Method Evaluations  

NSF Publications Database

... of Qualitative Methods and Analytic Techniques Common Qualitative Methods (Colleen Mahoney ... methods for a formative evaluation Evaluation questions, data sources, and data collection methods ...

173

A user-friendly Interactive Control Module for safeguards equipment  

SciTech Connect

The use of a microprocessor-based Interactive Control Module (ICM) to provide inspector interface to Containment and Surveillance equipment is described. This module has the operating procedures stored in system memory and uses a Liquid Crystal Display (LCD) with ''Soft Key'' input to guide the Inspector through the setup and review procedures in a prescribed order. A small printer is included to provide a hard-copy record of the setup, review, and diagnostic data. The use of this module should reduce the requirements for special training, minimize record keeping, and enhance inspector use of the equipment.

Holt, R.C.

1986-01-01

174

A user-friendly self-similarity analysis tool  

Microsoft Academic Search

The concepts of self-similarity, fractals, and long-range dependence (LRD) have revolutionized network modeling during the last decade. However, despite all the attention these concepts have received, they remain difficult to use by non-experts. This difficulty can be attributed to a relative complexity of the mathematical basis, the absence of a systematic approach to their application and the absence of publicly

Thomas Karagiannis; Michalis Faloutsos; Mart Molle

2003-01-01

175

Distance Education: A User-Friendly Learning Option  

ERIC Educational Resources Information Center

Environmental education is just beginning to tap the potential of the virtual classroom, with courses offered by University of Wisconsin-Stevens Point, Project Learning Tree, and others. The courses fill gaps in the learning opportunities available to formal and nonformal educators, and have drawn students, educators, resource management…

Gunderson, Kari

2006-01-01

176

USER FRIENDLY MODELS FOR EVALUATING HYDROGEOLOGIC BARRIERS TO VIRUSES  

EPA Science Inventory

Impending regulations in U.S. EPA's forthcoming Ground Water Rule (Federal Register, 2000) will require public water systems (PWS) to more closely monitor their groundwater systems for contamination by pathogens. As part of this process, State resource managers will assess the se...

177

A User-Friendly Model for Business/Education Partnerships.  

ERIC Educational Resources Information Center

In an effort to ensure local business involvement, the Steering Committee of the Tech Prep Consortium at Pasco-Hernando Community College (PHCC) in Central Florida invited members of the local business community to a Tech Prep Kickoff luncheon to sell them on Tech Prep. A tremendous number of companies attended the meeting and, to focus the energy…

Brooks, Gayle; Bell Carmine

178

ERIC SilverPlatter: Is It User Friendly?  

ERIC Educational Resources Information Center

This study conducted at Texas A&M University compares two types of training approaches using ERIC SilverPlatter (ERIC SP). Education students received either: (1) a one hour training session on basic search commands and strategies, or (2) a four page instructional handout that described basic search commands, Boolean logic, and special features…

Rholes, Julia M.; Caldwell-Wood, Naomi

179

User friendly Lidar system based on LabVIEW.  

National Technical Information Service (NTIS)

Mobile differential absorption lidar (DIAL) systems have been used for the last two decades. The lidar group in Lund has performed many DIAL measurements with a mobile lidar system which was first described in 1987. This report describes how that system w...

M. Andersson P. Weibring

1996-01-01

180

Tougher: A user-friendly graphical interface for TOUGHREACT  

NASA Astrophysics Data System (ADS)

TOUGHREACT is a powerful simulator for multiphase fluid, heat, and chemical transport, but has a steep learning curve and the creation of the input files is time intensive, particularly for heterogeneous and complex geometries such as those in mining rock pile formations. TOUGHER is an application developed by the acid rock drainage research group of the Department of Chemical Engineering at the University of Utah in order to develop TOUGHREACT models rapidly for two-dimensional problems and to be able to visualize the simulation results in an intuitive way. It also reduces errors when creating complex layered 2D models and makes debugging easier. The software is currently limited to 2D rectangular grids with constant spatial sizes. The application is written in C++ and can be used on any computer with a Windows or Linux operating system. This paper will describe the overall structure of the application and give some examples of how it interfaces with the TOUGHREACT program. In particular, it will be shown how the application can generate a grid system for a rock pile containing several distinct geological layers, how the properties of each layer are set, and how the input sections (ELEM and CONNE) for TOUGHREACT are generated automatically. In addition, visualizing the flow and chemical output files generated by TOUGHREACT for a particular rock pile will be demonstrated. This includes transient vector as well as transient scalar data. At the end of the paper, two case studies, one with a simplified geometry and another with more complex layered rock geometry, will be presented.

Li, You; Niewiadomski, Marcin; Trujillo, Edward; Sunkavalli, Surya Prakash

2011-06-01

181

Jupiter - Friend or Foe?  

NASA Astrophysics Data System (ADS)

It has long been believed that the planet Jupiter has played a beneficial role in the development of life on the Earth, acting as a shield from objects which would otherwise go on to significantly raise the impact flux experienced by our planet. Without Jupiter, the story goes, the Earth would have experienced a far greater number of impacts, making it far less hospitable to burgeoning life. In an on-going series of separate studies[1,2], we have examined the effects of varying the mass of Jupiter on the impact flux that the Earth would experience from Near-Earth Objects sourced from the Asteroid belt, short-period comets sourced from the Edgeworth-Kuiper belt, and long-period comets sourced from the Oort cloud. The results are remarkable - it seems that, far from being a shield, Jupiter actually acts to increase the impact flux experienced by the Earth over that which would be expected without the planet. Still more surprising, in the cases of the asteroids and Edgeworth-Kuiper belt objects, it seems that a Jupiter around 0.2 times the mass of "our Jupiter" would be even more threatening, sending a still greater number of objects our way. In order to simulate such disparate populations, different approaches to population construction were needed. The asteroidal and short-period comet populations each contained 100,000 test particles, moving on orbits typical of their class. The asteroids were initially distributed between 2 and 4 AU, with orbits of varying eccentricity and inclination, with number density varying as a function of semi-major axis. The short-period cometary flux was obtained through simulation of a population based on the subset of known Centaurs and Scattered Disk Objects which are Neptune-crossing, and have perihelia beyond the orbit of Uranus. These objects are the parents of the short-period comets, and were chosen since they are a population beyond the current influence of the planet Jupiter. Since our goal was to study the effect of Jupiter's mass on the impact flux at the Earth from the two populations, we followed our 100,000 particle populations for 10 million years, under the influence of the giant planets. Each particle was followed until it either hit something, or was ejected from the system. In this manner, we were able to follow the flux of objects onto the Earth as a function of time. The simulations were repeated over a wide range of Jupiter masses, with all other variables being held constant, allowing us to observe the variations in impact flux as a function of Jovian mass. In the cases of the asteroids and the short-period comets, Jupiter was observed to significantly modify the impact flux which would be experienced by the planet Earth. It was immediately obvious, however, that the old idea that Jupiter shields us from impacts no longer holds. For both of these populations, the lowest impact rates were experienced when the Jupiter-like planet in the system had the lowest mass, rose rapidly to a peak flux at around 0.2 Jupiter masses, before falling away more slowly. Therefore, for the asteroids and short-period comets, it seems that our Jupiter does offer some shielding, when compared to the case where the planet has a mass of around 0.2 MJ, but, compared to the scenario where no Jupiter is present at all (or the Jupiter in question has very low mass), Jupiter actually acts to increase the Earth-bound flux. Simulations are currently underway with the goal of analysing the effects of Jupiter's mass on the impact flux from the long-period comets (deflected inward towards the Earth from the Oort cloud). Further into the future, we intend to study the effects of Jovian position of the impact flux, with the goal of answering, once and for all, the question - "Jupiter - Friend or Foe?".

Horner, J.; Jones, B. W.

2008-09-01

182

Web-Based Family Life Education: Spotlight on User Experience  

ERIC Educational Resources Information Center

Family Life Education (FLE) websites can benefit from the field of user experience, which makes technology easy to use. A heuristic evaluation of five FLE sites was performed using Neilson's heuristics, guidelines for making sites user friendly. Greater site complexity resulted in more potential user problems. Sites most frequently had problems…

Doty, Jennifer; Doty, Matthew; Dwrokin, Jodi

2011-01-01

183

Free Our Friends in Learning  

ERIC Educational Resources Information Center

Many secrets can be told by the physical surroundings of library media centers. Whether the center is kid-friendly is one of the first obvious tell-tale signs. When a library center has Arthur & D.W., Clifford, Pooh & Eeyore, shells, special rocks, etc. hidden by the circulation center or in the back in boxes, it's time to revolt. The movie Free…

Stidham, Sue

2007-01-01

184

Friends of the National Library of Medicine  

MedlinePLUS

... Current Issue Past Issues Friends of the National Library of Medicine Past Issues / Summer 2006 Table of ... Paul G. Rogers Chairman, Friends of the National Library of Medicine and former member of the U.S. ...

185

Helping Family and Friends Understand Alzheimer's Disease  

MedlinePLUS

Helping Family and Friends Understand Alzheimer’s Disease Alzheimer’s Caregiving Tips When you learn that someone has Alzheimer’s disease, you may wonder when and how to tell your family and friends. You ...

186

My Friend Is Talking about Suicide  

MedlinePLUS

My Friend Is Talking About Suicide. What Should I Do? KidsHealth > Teens > Mind > Friends > My Friend Is Talking About Suicide. What Should I Do? Print A A ... You Can Do After Suicide Warning Signs of Suicide Everyone feels sad, depressed, or angry sometimes — especially ...

187

Adolescent Boys' Intentions of Seeking Help from Male Friends and Female Friends  

ERIC Educational Resources Information Center

This study examined adolescent boys' intentions of seeking help from male friends and female friends. We evaluated mean differences in boys' help-seeking intentions; assessed whether boys' individual characteristics predicted their intentions; and examined perceived support from male friends and female friends as mediators of these relationships.…

Sears, Heather A.; Graham, Joanna; Campbell, Anna

2009-01-01

188

A user-extensible graphical user interface for control of either instrument-control program, ACE or spec  

NASA Astrophysics Data System (ADS)

A single Graphical User Interface (GUI) has been developed to control the ACE [1-3] and spec [4] beamline-control and data-acquisition programs in use at Brookhaven National Laboratory's National Synchrotron Light Source (NSLS). The basic GUI provides a user-friendly interface to the primitive and macro-controlled operations of the programs. In addition, the GUI package provides facilities to allow users of the program to extend the GUI by construction of their own GUI screens so that they may have user-friendly interfaces to their customized macros. The GUI is easy to install and the authors expect to maintain it.

Skinner, John M.; LaBarca, Richard S.; Sweet, Robert M.

1996-02-01

189

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome  

PubMed Central

Background RNA-Seq is revolutionizing the way transcript abundances are measured. A key challenge in transcript quantification from RNA-Seq data is the handling of reads that map to multiple genes or isoforms. This issue is particularly important for quantification with de novo transcriptome assemblies in the absence of sequenced genomes, as it is difficult to determine which transcripts are isoforms of the same gene. A second significant issue is the design of RNA-Seq experiments, in terms of the number of reads, read length, and whether reads come from one or both ends of cDNA fragments. Results We present RSEM, an user-friendly software package for quantifying gene and isoform abundances from single-end or paired-end RNA-Seq data. RSEM outputs abundance estimates, 95% credibility intervals, and visualization files and can also simulate RNA-Seq data. In contrast to other existing tools, the software does not require a reference genome. Thus, in combination with a de novo transcriptome assembler, RSEM enables accurate transcript quantification for species without sequenced genomes. On simulated and real data sets, RSEM has superior or comparable performance to quantification methods that rely on a reference genome. Taking advantage of RSEM's ability to effectively use ambiguously-mapping reads, we show that accurate gene-level abundance estimates are best obtained with large numbers of short single-end reads. On the other hand, estimates of the relative frequencies of isoforms within single genes may be improved through the use of paired-end reads, depending on the number of possible splice forms for each gene. Conclusions RSEM is an accurate and user-friendly software tool for quantifying transcript abundances from RNA-Seq data. As it does not rely on the existence of a reference genome, it is particularly useful for quantification with de novo transcriptome assemblies. In addition, RSEM has enabled valuable guidance for cost-efficient design of quantification experiments with RNA-Seq, which is currently relatively expensive.

2011-01-01

190

Service on demand for ISS users  

Microsoft Academic Search

Since the ISS started its operational phase, the need of logistics scenarios and solutions, supporting the utilisation of the station and its facilities, becomes increasingly important. Our contribution to this challenge is a SERVICE On DEMAND for ISS users, which offers a business friendly engineering and logistics support for the resupply of the station. Especially the utilisation by commercial and

Detlev Hüser; Marco Berg; Nicole Körtge; Wolfgang Mildner; Frank Salmen; Karsten Strauch

2002-01-01

191

Crustal Dynamics Intelligent User Interface Anthology.  

National Technical Information Service (NTIS)

The National Space Science Data Center (NSSDC) has initiated an Intelligent Data Management (IDM) research effort which has, as one of its components, the development of an Intelligent User Interface (IUI). The intent of the IUI is to develop a friendly a...

N. M. Short, W. J. Campbell, L. H. Roelofs, S. L. Wattawa

1987-01-01

192

Grading More Accurately  

ERIC Educational Resources Information Center

Grades matter. College grading systems, however, are often ad hoc and prone to mistakes. This essay focuses on one factor that contributes to high-quality grading systems: grading accuracy (or "efficiency"). I proceed in several steps. First, I discuss the elements of "efficient" (i.e., accurate) grading. Next, I present analytical results…

Rom, Mark Carl

2011-01-01

193

QuShape: Rapid, accurate, and best-practices quantification of nucleic acid probing information, resolved by capillary electrophoresis  

PubMed Central

Chemical probing of RNA and DNA structure is a widely used and highly informative approach for examining nucleic acid structure and for evaluating interactions with protein and small-molecule ligands. Use of capillary electrophoresis to analyze chemical probing experiments yields hundreds of nucleotides of information per experiment and can be performed on automated instruments. Extraction of the information from capillary electrophoresis electropherograms is a computationally intensive multistep analytical process, and no current software provides rapid, automated, and accurate data analysis. To overcome this bottleneck, we developed a platform-independent, user-friendly software package, QuShape, that yields quantitatively accurate nucleotide reactivity information with minimal user supervision. QuShape incorporates newly developed algorithms for signal decay correction, alignment of time-varying signals within and across capillaries and relative to the RNA nucleotide sequence, and signal scaling across channels or experiments. An analysis-by-reference option enables multiple, related experiments to be fully analyzed in minutes. We illustrate the usefulness and robustness of QuShape by analysis of RNA SHAPE (selective 2?-hydroxyl acylation analyzed by primer extension) experiments.

Karabiber, Fethullah; McGinnis, Jennifer L.; Favorov, Oleg V.; Weeks, Kevin M.

2013-01-01

194

QuShape: rapid, accurate, and best-practices quantification of nucleic acid probing information, resolved by capillary electrophoresis.  

PubMed

Chemical probing of RNA and DNA structure is a widely used and highly informative approach for examining nucleic acid structure and for evaluating interactions with protein and small-molecule ligands. Use of capillary electrophoresis to analyze chemical probing experiments yields hundreds of nucleotides of information per experiment and can be performed on automated instruments. Extraction of the information from capillary electrophoresis electropherograms is a computationally intensive multistep analytical process, and no current software provides rapid, automated, and accurate data analysis. To overcome this bottleneck, we developed a platform-independent, user-friendly software package, QuShape, that yields quantitatively accurate nucleotide reactivity information with minimal user supervision. QuShape incorporates newly developed algorithms for signal decay correction, alignment of time-varying signals within and across capillaries and relative to the RNA nucleotide sequence, and signal scaling across channels or experiments. An analysis-by-reference option enables multiple, related experiments to be fully analyzed in minutes. We illustrate the usefulness and robustness of QuShape by analysis of RNA SHAPE (selective 2'-hydroxyl acylation analyzed by primer extension) experiments. PMID:23188808

Karabiber, Fethullah; McGinnis, Jennifer L; Favorov, Oleg V; Weeks, Kevin M

2013-01-01

195

"Friending Facebook?" A Minicourse on the Use of Social Media by Health Professionals  

ERIC Educational Resources Information Center

Introduction: Health professionals are working in an era of social technologies that empower users to generate content in real time. This article describes a 3-part continuing education minicourse called "Friending Facebook?" undertaken at Penn State Hershey Medical Center that aimed to model the functionality of current technologies in health…

George, Daniel R.

2011-01-01

196

Nonexposure Accurate Location K-Anonymity Algorithm in LBS  

PubMed Central

This paper tackles location privacy protection in current location-based services (LBS) where mobile users have to report their exact location information to an LBS provider in order to obtain their desired services. Location cloaking has been proposed and well studied to protect user privacy. It blurs the user's accurate coordinate and replaces it with a well-shaped cloaked region. However, to obtain such an anonymous spatial region (ASR), nearly all existent cloaking algorithms require knowing the accurate locations of all users. Therefore, location cloaking without exposing the user's accurate location to any party is urgently needed. In this paper, we present such two nonexposure accurate location cloaking algorithms. They are designed for K-anonymity, and cloaking is performed based on the identifications (IDs) of the grid areas which were reported by all the users, instead of directly on their accurate coordinates. Experimental results show that our algorithms are more secure than the existent cloaking algorithms, need not have all the users reporting their locations all the time, and can generate smaller ASR.

2014-01-01

197

Nonexposure accurate location K-anonymity algorithm in LBS.  

PubMed

This paper tackles location privacy protection in current location-based services (LBS) where mobile users have to report their exact location information to an LBS provider in order to obtain their desired services. Location cloaking has been proposed and well studied to protect user privacy. It blurs the user's accurate coordinate and replaces it with a well-shaped cloaked region. However, to obtain such an anonymous spatial region (ASR), nearly all existent cloaking algorithms require knowing the accurate locations of all users. Therefore, location cloaking without exposing the user's accurate location to any party is urgently needed. In this paper, we present such two nonexposure accurate location cloaking algorithms. They are designed for K-anonymity, and cloaking is performed based on the identifications (IDs) of the grid areas which were reported by all the users, instead of directly on their accurate coordinates. Experimental results show that our algorithms are more secure than the existent cloaking algorithms, need not have all the users reporting their locations all the time, and can generate smaller ASR. PMID:24605060

Jia, Jinying; Zhang, Fengli

2014-01-01

198

Accurate Guitar Tuning by Cochlear Implant Musicians  

PubMed Central

Modern cochlear implant (CI) users understand speech but find difficulty in music appreciation due to poor pitch perception. Still, some deaf musicians continue to perform with their CI. Here we show unexpected results that CI musicians can reliably tune a guitar by CI alone and, under controlled conditions, match simultaneously presented tones to <0.5 Hz. One subject had normal contralateral hearing and produced more accurate tuning with CI than his normal ear. To understand these counterintuitive findings, we presented tones sequentially and found that tuning error was larger at ?30 Hz for both subjects. A third subject, a non-musician CI user with normal contralateral hearing, showed similar trends in performance between CI and normal hearing ears but with less precision. This difference, along with electric analysis, showed that accurate tuning was achieved by listening to beats rather than discriminating pitch, effectively turning a spectral task into a temporal discrimination task.

Lu, Thomas; Huang, Juan; Zeng, Fan-Gang

2014-01-01

199

User Understanding.  

ERIC Educational Resources Information Center

This document presents hypotheses about how much understanding a user needs to perform skillfully using a computer or a computer program. A framework for characterizing user understanding is presented which includes three criteria for evaluating the representation generated during problem solving: (1) internal coherence--whether the components of…

Riley, Mary S.

200

Accurate monotone cubic interpolation  

NASA Technical Reports Server (NTRS)

Monotone piecewise cubic interpolants are simple and effective. They are generally third-order accurate, except near strict local extrema where accuracy degenerates to second-order due to the monotonicity constraint. Algorithms for piecewise cubic interpolants, which preserve monotonicity as well as uniform third and fourth-order accuracy are presented. The gain of accuracy is obtained by relaxing the monotonicity constraint in a geometric framework in which the median function plays a crucial role.

Huynh, Hung T.

1991-01-01

201

Accurate Finite Difference Algorithms  

NASA Technical Reports Server (NTRS)

Two families of finite difference algorithms for computational aeroacoustics are presented and compared. All of the algorithms are single step explicit methods, they have the same order of accuracy in both space and time, with examples up to eleventh order, and they have multidimensional extensions. One of the algorithm families has spectral like high resolution. Propagation with high order and high resolution algorithms can produce accurate results after O(10(exp 6)) periods of propagation with eight grid points per wavelength.

Goodrich, John W.

1996-01-01

202

Accurate Unlexicalized Parsing  

Microsoft Academic Search

We demonstrate that an unlexicalized PCFG can parse much more accurately than previously shown, by making use of simple, linguistically motivated state splits, which break down false independence assumptions latent in a vanilla treebank grammar. Indeed, its performance of 86.36% (LP\\/LR F PCFG models, and surprisingly close to the current state-of-the-art. This result has potential uses beyond establishing a strong

Dan Klein; Christopher D. Manning

2003-01-01

203

Towards tooth friendly soft drinks.  

PubMed

Most soft drinks contain high concentration of simple carbohydrates and have a pH of 3 or even lower. Therefore, they are harmful for tooth structure. A tooth friendly soft drink (T.F.S.D) should have the following characteristics and elements; fluoride (approximately 1 ppm), casein phosphopeptide-amorphous calcium phosphate (2%), xylitol (4-6g/serving), tea polyphenols (2-4 mg/ml), cranberry extract (250 mg/ml of the flavonoids quercetin and myricetin), sugar free, pH close to 5.5 and super oxygenation (240,000 ppm) vs. carbonation. T.F.S.D can be packaged in a container which gaseous oxygen is dissolved in a liquid in the form of bubbles. However, looking at opportunities for so-called sophisticated soft drinks, T.F.S.D will be an example for a functional and health oriented soft drink. PMID:19570614

Kolahi, Jafar; Fazilati, Mohamad; Kadivar, Mahdi

2009-10-01

204

Dementia-friendly design resource.  

PubMed

Although estimates suggest that, on average, some 30 per cent of all patients in general acute medical wards may have some form of dementia, Stirling University's Dementia Services Development Centre (DSDC), one of the leading international knowledge centres working to improve the lives of dementia sufferers, says progress in designing healthcare facilities that address such patients' needs has been 'patchy at best'. With the number of individuals living with dementia expected to double in the next 25 years, the DSDC has recently worked with Edinburgh-based architects, Burnett Pollock Associates, to develop an online resource that clearly illustrates, via 15 simulated 'dementia-friendly' healthcare 'spaces', some of the key principles to consider when designing effectively for this fast-growing group. HEJ editor, Jonathan Baillie, attended the launch of the so-called 'Virtual Hospital'. PMID:24620491

Baillie, Jonathan

2014-02-01

205

Good Agreements Make Good Friends  

PubMed Central

When starting a new collaborative endeavor, it pays to establish upfront how strongly your partner commits to the common goal and what compensation can be expected in case the collaboration is violated. Diverse examples in biological and social contexts have demonstrated the pervasiveness of making prior agreements on posterior compensations, suggesting that this behavior could have been shaped by natural selection. Here, we analyze the evolutionary relevance of such a commitment strategy and relate it to the costly punishment strategy, where no prior agreements are made. We show that when the cost of arranging a commitment deal lies within certain limits, substantial levels of cooperation can be achieved. Moreover, these levels are higher than that achieved by simple costly punishment, especially when one insists on sharing the arrangement cost. Not only do we show that good agreements make good friends, agreements based on shared costs result in even better outcomes.

Han, The Anh; Pereira, Luis Moniz; Santos, Francisco C.; Lenaerts, Tom

2013-01-01

206

Who Goes There: Friend or Foe.  

National Technical Information Service (NTIS)

The recent Persian Gulf War focused attention on the problem of fratricide, or 'friendly fire' casualties among combat units. Twenty-four percent of U.S. combat fatalities in that conflict were due to friendly fire. The House Armed Services Committee requ...

1993-01-01

207

Best Friend Networks of Children across Settings.  

ERIC Educational Resources Information Center

Investigated children's classroom sociometry and size of their best-friend networks. For both classroom and playground settings, popular children had the most reciprocal best friends, while rejected children had the fewest, but had more on the playground than in the classroom. Results suggest that constraints and opportunities of different…

Ray, Glen E.; And Others

1995-01-01

208

Constructing Family-Friendly Careers: Mothers' Experiences  

ERIC Educational Resources Information Center

This study explored the experience of 26 married mothers who had developed family-friendly careers. Family-friendly careers were defined as careers that required less than 30 hours per week and were structured to allow the participants to spend "significant" amounts of time with their families. Guided interviews were used to obtain in-depth…

Jackson, Aaron P.; Scharman, Janet S.

2002-01-01

209

Relations of Friends' Activities to Friendship Quality  

ERIC Educational Resources Information Center

Two studies were conducted to examine age and sex differences in friends' activities and relations of participation in these activities to perceived friendship quality. In Study 1, 52 fourth and eighth graders were asked open-ended questions about activities they do with their best friends. In Study 2, 105 fourth and eighth graders reported both…

Mathur, Ravisha; Berndt, Thomas J.

2006-01-01

210

Best Friends: Children Use Mutual Gaze to Identify Friendships in Others  

ERIC Educational Resources Information Center

This study examined children's ability to use mutual eye gaze as a cue to friendships in others. In Experiment 1, following a discussion about friendship, 4-, 5-, and 6-year-olds were shown animations in which three cartoon children looked at one another, and were told that one target character had a best friend. Although all age groups accurately

Nurmsoo, Erika; Einav, Shiri; Hood, Bruce M.

2012-01-01

211

Recommendations from Friends Anytime and Anywhere: Toward a Model of Contextual Offer and Consumption Values  

PubMed Central

Abstract The ubiquity and portability of mobile devices provide additional opportunities for information retrieval. People can easily access mobile applications anytime and anywhere when they need to acquire specific context-aware recommendations (contextual offer) from their friends. This study, thus, represents an initial attempt to understand users' acceptance of a mobile-based social reviews platform, where recommendations from friends can be obtained with mobile devices. Based on the consumption value theory, a theoretical model is proposed and empirically examined using survey data from 218 mobile users. The findings demonstrate that contextual offers based on users' profiles, access time, and geographic positions significantly predict their value perceptions (utilitarian, hedonic, and social), which, in turn, affect their intention to use a mobile social reviews platform. This study is also believed to provide some useful insights to both research and practice.

Shen, Xiao-Liang; Wang, Nan

2013-01-01

212

Creating Student-Friendly Tests  

ERIC Educational Resources Information Center

Creating a fair, reliable, teacher-made test is a challenge. Every year poorly designed tests fail to accurately measure many students' learning--and negatively affect their academic futures. Salend, a well-known writer on assessment for at-risk students who consults with schools on assessment procedures, offers guidelines for creating tests that…

Salend, Spencer J.

2011-01-01

213

Accurate measurement of time  

NASA Astrophysics Data System (ADS)

The paper discusses current methods for accurate measurements of time by conventional atomic clocks, with particular attention given to the principles of operation of atomic-beam frequency standards, atomic hydrogen masers, and atomic fountain and to the potential use of strings of trapped mercury ions as a time device more stable than conventional atomic clocks. The areas of application of the ultraprecise and ultrastable time-measuring devices that tax the capacity of modern atomic clocks include radio astronomy and tests of relativity. The paper also discusses practical applications of ultraprecise clocks, such as navigation of space vehicles and pinpointing the exact position of ships and other objects on earth using the GPS.

Itano, Wayne M.; Ramsey, Norman F.

1993-07-01

214

Accurate quantum chemical calculations  

NASA Technical Reports Server (NTRS)

An important goal of quantum chemical calculations is to provide an understanding of chemical bonding and molecular electronic structure. A second goal, the prediction of energy differences to chemical accuracy, has been much harder to attain. First, the computational resources required to achieve such accuracy are very large, and second, it is not straightforward to demonstrate that an apparently accurate result, in terms of agreement with experiment, does not result from a cancellation of errors. Recent advances in electronic structure methodology, coupled with the power of vector supercomputers, have made it possible to solve a number of electronic structure problems exactly using the full configuration interaction (FCI) method within a subspace of the complete Hilbert space. These exact results can be used to benchmark approximate techniques that are applicable to a wider range of chemical and physical problems. The methodology of many-electron quantum chemistry is reviewed. Methods are considered in detail for performing FCI calculations. The application of FCI methods to several three-electron problems in molecular physics are discussed. A number of benchmark applications of FCI wave functions are described. Atomic basis sets and the development of improved methods for handling very large basis sets are discussed: these are then applied to a number of chemical and spectroscopic problems; to transition metals; and to problems involving potential energy surfaces. Although the experiences described give considerable grounds for optimism about the general ability to perform accurate calculations, there are several problems that have proved less tractable, at least with current computer resources, and these and possible solutions are discussed.

Bauschlicher, Charles W., Jr.; Langhoff, Stephen R.; Taylor, Peter R.

1989-01-01

215

An automatic and user-driven training method for locomotion mode recognition for artificial leg control.  

PubMed

Our previously developed locomotion-mode-recognition (LMR) system has provided a great promise to intuitive control of powered artificial legs. However, the lack of fast, practical training methods is a barrier for clinical use of our LMR system for prosthetic legs. This paper aims to design a new, automatic, and user-driven training method for practical use of LMR system. In this method, a wearable terrain detection interface based on a portable laser distance sensor and an inertial measurement unit (IMU) is applied to detect the terrain change in front of the prosthesis user. The mechanical measurement from the prosthetic pylon is used to detect gait phase. These two streams of information are used to automatically identify the transitions among various locomotion modes, switch the prosthesis control mode, and label the training data with movement class and gait phase in real-time. No external device is required in this training system. In addition, the prosthesis user without assistance from any other experts can do the whole training procedure. The pilot experimental results on an able-bodied subject have demonstrated that our developed new method is accurate and user-friendly, and can significantly simplify the LMR training system and training procedure without sacrificing the system performance. The novel design paves the way for clinical use of our designed LMR system for powered lower limb prosthesis control. PMID:23367324

Zhang, Xiaorong; Wang, Ding; Yang, Qing; Huang, He

2012-01-01

216

An Automatic and User-Driven Training Method for Locomotion Mode Recognition for Artificial Leg Control  

PubMed Central

Our previously developed locomotion-mode-recognition (LMR) system has provided a great promise to intuitive control of powered artificial legs. However, the lack of fast, practical training methods is a barrier for clinical use of our LMR system for prosthetic legs. This paper aims to design a new, automatic, and user-driven training method for practical use of LMR system. In this method, a wearable terrain detection interface based on a portable laser distance sensor and an inertial measurement unit (IMU) is applied to detect the terrain change in front of the prosthesis user. The mechanical measurement from the prosthetic pylon is used to detect gait phase. These two streams of information are used to automatically identify the transitions among various locomotion modes, switch the prosthesis control mode, and label the training data with movement class and gait phase in real-time. No external device is required in this training system. In addition, the prosthesis user without assistance from any other experts can do the whole training procedure. The pilot experimental results on an able-bodied subject have demonstrated that our developed new method is accurate and user-friendly, and can significantly simplify the LMR training system and training procedure without sacrificing the system performance. The novel design paves the way for clinical use of our designed LMR system for powered lower limb prosthesis control.

Zhang, Xiaorong; Wang, Ding; Yang, Qing; Huang, He

2013-01-01

217

ETPRE User`s Manual Version 3.00  

SciTech Connect

ETPRE is a preprocessor for the Event Progression Analysis Code EVNTRE. It reads an input file of event definitions and writes the lengthy EVNTRE code input files. ETPRE`s advantage is that it eliminates the error-prone task of manually creating or revising these files since their formats are quite elaborate. The user-friendly format of ETPRE differs from the EVNTRE code format in that questions, branch references, and other event tree components are defined symbolically instead of numerically. When ETPRE is executed, these symbols are converted to their numeric equivalents and written to the output files using formats defined in the EVNTRE Reference Manual. Revisions to event tree models are simplified by allowing the user to edit the symbolic format and rerun the preprocessor, since questions, branch references, and other symbols are automatically resequenced to their new values with each execution. ETPRE and EVNTRE have both been incorporated into the SETAC event tree analysis package.

Roginski, R.J.

1994-05-01

218

ETPRE User`s Manual Version 2.00  

SciTech Connect

ETPRE is a preprocessor for the Event Progression Analysis Code EVNTRE. It reads an input file of event definitions and writes the lengthy EVNTRE code input files. ETPRE`s advantage is that it eliminates the error-prone task of manually creating or revising these files since their formats are quite elaborate. The user-friendly format of ETPRE differs from the EVNTRE code format in that questions, branch references, and other event tree components are defined symbolically instead of numerically. When ETPRE is executed, these symbols are converted to their numeric equivalents and written to the output files using format defined in the EVNTRE Reference Manual. Revisions to event tree models are simplified by allowing the user to edit the symbolic format and rerun the preprocessor, since questions, branch references, and other symbols are automatically resequenced to their new values with each execution.

Roginski, R.J.

1993-02-01

219

View southwest toward Eldred Avenue from within Friend's Burial Ground, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

View southwest toward Eldred Avenue from within Friend's Burial Ground, Benjamin Carr Farm in distance through the trees - Friends' Burial Ground, Eldred & Beacon Avenues, Jamestown, Newport County, RI

220

Distributed rating prediction in user generated content streams  

Microsoft Academic Search

Recommender systems predict user preferences based on a range of available information. For systems in which users generate streams of content (e.g., blogs, periodically-updated newsfeeds), users may rate the produced content that they read, and be given accurate predictions about future content they are most likely to prefer. We design a distributed mechanism for predicting user ratings that avoids the

Sibren Isaacman; Stratis Ioannidis; Augustin Chaintreau; Margaret Martonosi

2011-01-01

221

GRAPS (Graphical Plotting System) User's Guide. A Graphical Plotting System for Displaying Scientific and Engineering Data.  

National Technical Information Service (NTIS)

This document provides an introduction and update to the Graphical Plotting System (GRAPS), a plotting utility developed by the Naval Ocean Systems Center for the personal computer. GRAPS provides a convenient, user-friendly tool for the display of engine...

J. Strauch J. C. Logan

1988-01-01

222

Your Genes May Help Pick Your Friends  

MedlinePLUS

... features on this page, please enable JavaScript. Your Genes May Help Pick Your Friends Study says DNA ... Preidt Monday, July 14, 2014 Related MedlinePlus Page Genes and Gene Therapy MONDAY, July 14, 2014 (HealthDay ...

223

Environmentally friendly preparation of metal nanoparticles  

EPA Science Inventory

The book chapter summarizes the ?state of the art? in the exploitation of various environmentally-friendly synthesis approaches, reaction precursors and conditions to manufacture metal and metal oxide nanoparticles for a vast variety of purposes....

224

User Characteristics: Professional vs. Lay Users  

Microsoft Academic Search

The market success of a product largely depends on whether it correctly addresses the user needs. Understanding the user is increasingly becoming important in the design process. Different user models may determine different approaches to design. This paper identifies the characteristics of different types of users, with a specific focus on professional users and lay users. It gives a definition

Selami Cifter; Hua Dong

225

RAPID AND ACCURATE METHOD FOR ESTIMATING MOLECULAR WEIGHTS OF ORGANIC COMPOUNDS FROM LOW RESOLUTION MASS SPECTRA  

EPA Science Inventory

An improved method of estimating molecular weights of volatile organic compounds from their mass spectra has been developed and evaluated for accuracy. his technique can be implemented with a user friendly expert system on a personal computer. he method is based on a pattern reco...

226

Micromechanical combined stress analysis: MICSTRAN, a user manual  

NASA Technical Reports Server (NTRS)

Composite materials are currently being used in aerospace and other applications. The ability to tailor the composite properties by the appropriate selection of its constituents, the fiber and matrix, is a major advantage of composite materials. The Micromechanical Combined Stress Analysis (MICSTRAN) code provides the materials engineer with a user-friendly personal computer (PC) based tool to calculate overall composite properties given the constituent fiber and matrix properties. To assess the ability of the composite to carry structural loads, the materials engineer also needs to calculate the internal stresses in the composite material. MICSTRAN is a simple tool to calculate such internal stresses with a composite ply under combined thermomechanical loading. It assumes that the fibers have a circular cross-section and are arranged either in a repeating square or diamond array pattern within a ply. It uses a classical elasticity solution technique that has been demonstrated to calculate accurate stress results. Input to the program consists of transversely isotropic fiber properties and isotropic matrix properties such as moduli, Poisson's ratios, coefficients of thermal expansion, and volume fraction. Output consists of overall thermoelastic constants and stresses. Stresses can be computed under the combined action of thermal, transverse, longitudinal, transverse shear, and longitudinal shear loadings. Stress output can be requested along the fiber-matrix interface, the model boundaries, circular arcs, or at user-specified points located anywhere in the model. The MICSTRAN program is Windows compatible and takes advantage of the Microsoft Windows graphical user interface which facilitates multitasking and extends memory access far beyond the limits imposed by the DOS operating system.

Naik, R. A.

1992-01-01

227

Network User Information Support.  

National Technical Information Service (NTIS)

With increasing interest in the development of computer networks and the proliferation of remote entry capability from user terminals, user support takes on new dimensions. Some user characteristics are outlined as they affect user support. User support r...

A. J. Neumann

1973-01-01

228

How to Make Financial Aid "Freshman-Friendly"  

ERIC Educational Resources Information Center

Ultimately, making financial aid "freshman friendly" also makes financial aid "sophomore friendly," "junior friendly," and "senior friendly." Indiana University has in place an Office of Enrollment Management (OEM) model that includes focused financial aid packaging strategies complemented by unique contact services and communication interventions…

Pugh, Susan L.; Johnson, David B.

2011-01-01

229

Friends and neighbors on the Web  

Microsoft Academic Search

The Internet has become a rich and large repository of information about us as individuals. Anything from the links and text on a user’s homepage to the mailing lists the user subscribes to are reflections of social interactions a user has in the real world. In this paper we devise techniques and tools to mine this information in order to

Lada A. Adamic; Eytan Adar

2003-01-01

230

Improving situation awareness using a hub architecture for friendly force tracking  

NASA Astrophysics Data System (ADS)

Situation Awareness (SA) is the perception of environmental elements within a volume of time and space, the comprehension of their meaning, and the projection of their future status. In a military environment the most critical elements to be tracked are followed elements are either friendly or hostile forces. Poor knowledge of locations of friendly forces easily leads into the situation in which the troops could be under firing by own troops or in which decisions in a command and control system are based on incorrect tracking. Thus the Friendly Force Tracking (FFT) is a vital part of building situation awareness. FFT is basically quite simple in theory; collected tracks are shared through the networks to all troops. In real world, the situation is not so clear. Poor communication capabilities, lack of continuous connectivity n and large number of user on different level provide high requirements for FFT systems. In this paper a simple architecture for Friendly Force Tracking is presented. The architecture is based on NFFI (NATO Friendly Force Information) hubs which have two key features; an ability to forward tracking information and an ability to convert information into the desired format. The hub based approach provides a lightweight and scalable solution, which is able to use several types of communication media (GSM, tactical radios, TETRA etc.). The system is also simple to configure and maintain. One main benefit of the proposed architecture is that it is independent on a message format. It communicates using NFFI messages, but national formats are also allowed.

Karkkainen, Anssi P.

2010-04-01

231

Fast and accurate 3D gesture recognition interface  

Microsoft Academic Search

A video-based gesture recognition system can serve as a natural and accurate 3D user input device. We describe a two-camera system, that recognizes three gesture classes: two static and one dynamic. For one of these gestures (pointing), the system estimates five parameters of 3D pose: position and pointing direction. The recognition is robust, independent of the user and fast (60

Jakub Segen; Senthil Kumar

1998-01-01

232

Maternal affection moderates friend influence on schoolwork engagement.  

PubMed

This study investigated friend influence over adolescent schoolwork engagement in 160 same-sex friend dyads (94 female dyads and 66 male dyads). Participants were approximately 16 years of age at the outset. Each friend described his or her own schoolwork engagement, school burnout, and perceptions of maternal affection. The results revealed that maternal affection moderated the influence that the higher burnout friend exerted over the subsequent schoolwork engagement of the lower burnout friend. The schoolwork engagement of the friend reporting higher levels of school burnout predicted a decline in the schoolwork engagement of the friend reporting lower school burnout, but only if the latter perceived below-average maternal affection. PMID:24015690

Marion, Donna; Laursen, Brett; Kiuru, Noona; Nurmi, Jari-Erik; Salmela-Aro, Katariina

2014-03-01

233

The more friends, the less political talk? Predictors of facebook discussions among college students.  

PubMed

Abstract Although previous research has indicated that Facebook users, especially young adults, can cultivate their civic values by talking about public matters with their Facebook friends, little research has examined the predictors of political discussion on Facebook. Using survey data from 442 college students in the United States, this study finds that individual characteristics and network size influence college students' expressive behavior on Facebook related to two controversial topics: gay rights issues and politics. In line with previous studies about offline political discussion, the results show that conflict avoidance and ambivalence about target issues are negatively associated with Facebook discussions. Perhaps the most interesting finding is that users who have a large number of Facebook friends are less likely to talk about politics and gay rights issues on Facebook despite having access to increasing human and information resources. Theoretical implications of these findings and future directions are addressed. PMID:24479528

Jang, S Mo; Lee, Hoon; Park, Yong Jin

2014-05-01

234

Genometa - A Fast and Accurate Classifier for Short Metagenomic Shotgun Reads  

PubMed Central

Summary Metagenomic studies use high-throughput sequence data to investigate microbial communities in situ. However, considerable challenges remain in the analysis of these data, particularly with regard to speed and reliable analysis of microbial species as opposed to higher level taxa such as phyla. We here present Genometa, a computationally undemanding graphical user interface program that enables identification of bacterial species and gene content from datasets generated by inexpensive high-throughput short read sequencing technologies. Our approach was first verified on two simulated metagenomic short read datasets, detecting 100% and 94% of the bacterial species included with few false positives or false negatives. Subsequent comparative benchmarking analysis against three popular metagenomic algorithms on an Illumina human gut dataset revealed Genometa to attribute the most reads to bacteria at species level (i.e. including all strains of that species) and demonstrate similar or better accuracy than the other programs. Lastly, speed was demonstrated to be many times that of BLAST due to the use of modern short read aligners. Our method is highly accurate if bacteria in the sample are represented by genomes in the reference sequence but cannot find species absent from the reference. This method is one of the most user-friendly and resource efficient approaches and is thus feasible for rapidly analysing millions of short reads on a personal computer. Availability The Genometa program, a step by step tutorial and Java source code are freely available from http://genomics1.mh-hannover.de/genometa/ and on http://code.google.com/p/genometa/. This program has been tested on Ubuntu Linux and Windows XP/7.

Davenport, Colin F.; Neugebauer, Jens; Beckmann, Nils; Friedrich, Benedikt; Kameri, Burim; Kokott, Svea; Paetow, Malte; Siekmann, Bjorn; Wieding-Drewes, Matthias; Wienhofer, Markus; Wolf, Stefan; Tummler, Burkhard; Ahlers, Volker; Sprengel, Frauke

2012-01-01

235

AutoGait: A mobile platform that accurately estimates the distance walked  

Microsoft Academic Search

AutoGait is a mobile platform that autonomously discovers a user's walking profile and accurately estimates the distance walked. The discovery is made by utilizing the GPS in the user's mobile device when the user is walking outdoors. This profile can then be used both indoors and outdoors to estimate the distance walked. To model the person's walking profile, we take

Dae-Ki Cho; Min Mun; Uichin Lee; Williams J. Kaiser; Mario Gerla

2010-01-01

236

Transsexualism and Gender Transition FAQ for Significant Others, Friends, Family, Employers, Coworkers  

NSDL National Science Digital Library

This FAQ, written by members of the Mid-Michigan FTM (female-to-male) Alliance, offers general information about transsexualism and gender transition, and addresses the common responses and concerns that friends, family, and co-workers have about the transgendered person in their lives. An annotated webliography of relevant resources and a bibliography about transsexualism guide users to additional information. A text-only version of the entire site is available to facilitate printing.

1998-01-01

237

Time-Lined TCP for the TCP-Friendly Delivery of Streaming Media  

Microsoft Academic Search

This paper introduces Time-lined TCP (TLTCP). TLTCP is a protocol designed to provide TCP-friendly delivery of time- sensitive data to applications that are loss-tolerant, such as streaming media players. Previous work on unicast delivery of streaming media over the Internet proposes using UDP and per- forms congestion control at the user level by regulating the appli- cation's sending rate (attempting

Biswaroop Mukherjee; Tim Brecht

2000-01-01

238

Embodied User Interfaces: Towards Invisible User Interfaces  

Microsoft Academic Search

There have been several recent examples of user interface techniques in which the user uses a computational device by physically manipulating the device. This paper proposes that these form an interesting new paradigm for user interface design, Embodied User Interfaces. This paper presents and defines this paradigm, and places it in the evolution of user interface paradigms leading towards the

Kenneth P. Fishkin; Thomas P. Moran; Beverly L. Harrison

1998-01-01

239

Health Promotion via Deaf-Friendly Ministries  

PubMed Central

Deaf community members face many barriers to accessing health information. This paper discusses the feasibility of creating a nationwide network of Deaf-friendly ministries to help disseminate cancer information in American Sign Language (ASL) to the Deaf community. Deaf-friendly ministries (N=403), identified through Internet searches and one-on-one referrals, were sent up to three mailed invitations to join the network. Over half of the ministries responded, with 191 (47.4 %) of the ministries joining the network, completing a baseline survey and receiving ASL cancer education videos to share with members of their congregation and community. Fifteen (3.7 %) responded that they were not interested or no longer had a Deaf-friendly ministry; the rest did not respond or their invitations were returned as undeliverable. As the program progressed, an additional 238 Deaf-friendly ministries were identified. To date, 61 (25.6 %) agreed to participate after the single invitation that was mailed. This network of Deaf-friendly ministries offers a promising dissemination partner.

Branz, Patricia; Fager, Matthew; Seegers, Sharon; Shimasaki, Suzuho

2013-01-01

240

Young Friendship in HFASD and Typical Development: Friend Versus Non-friend Comparisons.  

PubMed

This study conducted comparative assessment of friendship in preschoolers with high-functioning autism spectrum disorder (HFASD, n = 29) versus preschoolers with typical development (n = 30), focusing on interactions with friends versus acquaintances. Groups were matched on SES, verbal/nonverbal MA, IQ, and CA. Multidimensional assessments included: mothers' and teachers' reports about friends' and friendship characteristics and observed individual and dyadic behaviors throughout interactions with friends versus non-friends during construction, drawing, and free-play situations. Findings revealed group differences in peer interaction favoring the typical development group, thus supporting the neuropsychological profile of HFASD. However, both groups' interactions with friends surpassed interactions with acquaintances on several key socio-communicative and intersubjective capabilities, thus suggesting that friendship may contribute to enhancement and practice of social interaction in HFASD. PMID:24488120

Bauminger-Zviely, Nirit; Agam-Ben-Artzi, Galit

2014-07-01

241

PAGAS: Portable and Accurate Gait Analysis System.  

PubMed

Gait analysis systems are powerful tools in the monitoring and rehabilitation of many health conditions which result in an altered gait (such as Parkinson's disease and rheumatoid arthritis), along with the injury of lower limbs. However, current systems that provide accurate gait monitoring and analysis are large and expensive, and therefore are available only in professional settings. The goal of this research is to develop and test a Portable and Accurate Gait Analysis System, denoted PAGAS, which enables patients to monitor their own gait and track their progress and improvement over time. Moreover, PAGAS will enable therapists to follow the progress of their patients over time without the need for multiple visits required at a rehabilitation facility, thus saving significant healthcare costs. PAGAS includes footswitches and a micro-controller, which connects to an Android Smart-phone using Bluetooth communication. An application on the Smartphone analyzes the raw data to produce temporal gait parameters that are displayed to the user on a graphical user interface. PMID:23365885

Wagner, Rojay; Ganz, Aura

2012-01-01

242

Step 2: Provides Accurate, Descriptive, Statistical Information About Birth Care Practices  

PubMed Central

Step 2 of the Ten Steps of Mother-Friendly Care insures that women will have accurate, descriptive, and statistical information about the practices and procedures for birth care at their place of birth, including measures of interventions and outcomes. This information provides a foundation for making informed decisions. The rationales and evidence in support of this step are presented.

2007-01-01

243

Consummated friends and ex-wives.  

PubMed

Abstract This article focuses on the different roles of lesbian ex-lovers in the writer's life. She divides her exes into two categories: consummated friends and ex-wives. The determining factor is whether or not the lovers lived together as a committed couple. Consummated friends are no exception to her belief that every relationship has significance, and this article shares how even relatively brief affairs expand concepts about sex, relationships, and self. Although many lesbians keep ex-wives in their intimate circles, she resists this practice. Consummated friends, however, continue to be an active part of her life. This article reveals the personal how's and why's regarding one woman's choices in connection (and disconnection) with her exes. PMID:24821048

Eden, Tabitha

2004-01-01

244

Symbolic User-Defined Periodicity in Temporal Relational Databases  

Microsoft Academic Search

Abstract—Calendars and periodicity play a fundamental role in many applications. Recently, some commercial databases started to support user-defined periodicity in the queries in order to provide “a human-friendly way of handling time” (see, e.g., TimeSeries in Oracle 8). On the other hand, only few relational data models support user-defined periodicity in the data, mostly using “mathematical” expressions to represent periodicity.

Paolo Terenziani

2003-01-01

245

Accurate \\  

Microsoft Academic Search

We analyse a system in which, due to entanglement between the spin and\\u000aspatial degrees of freedom, the reduced transmitted state has the shape of the\\u000afreely propagating pulse translated in the complex co-ordinate plane. In the\\u000acase an apparently \\

D. Sokolovski; R. Sala Mayato

2009-01-01

246

CACOPS: A General Purpose Cycle-Accurate Configurable Power Simulator  

Microsoft Academic Search

This paper presents a cycle-accurate and configurable simulator that estimates the power consumed by an embedded system. The simulator accepts as input a structural system architecture description, at a level of abstraction that can be configured by the user. The simulator has been used to study the power dissipation of different micro-architectures of a Java microcontroller while executing several applications.

Antonio C. S. Beck Filho; Jślio C. B. de Mattos; Flįvio Rech Wagner; Luigi Carro

2003-01-01

247

Comprehensible and Accurate Cluster Labels in Text Clustering  

Microsoft Academic Search

The purpose of text clustering in information retrieval is to discover groups of se- mantically related documents. Accurate and comprehensible cluster descriptions (labels) let the user comprehend the collection's content faster and are essential for various doc- ument browsing interfaces. The task of creating descriptive, sensible cluster labels is dicult—typical text clustering algorithms focus on optimizing proximity between doc- uments

Jerzy Stefanowski; Dawid Weiss

2007-01-01

248

Applying Brain-Friendly Instructional Practices  

ERIC Educational Resources Information Center

In this article, the author offers advice for principals on working with teachers to change the instructional climate and on how to apply brain-friendly instructions to improve the effectiveness of one's teaching. To lead an entire district toward the use of brain-compatible instruction, the author suggests to start with a group of motivated…

Erlauer-Myrah, Laura

2006-01-01

249

Earnings management by friendly takeover targets  

Microsoft Academic Search

Purpose – Accounting research has emphasized target and bidder managers' incentives to manipulate earnings during corporate control contests. However, prior studies examining earnings management by takeover targets have obtained mixed results. Moreover, the existing evidence is mainly based on US data and hostile mergers and acquisitions (M&A) transactions. The purpose of this study is to examine earnings management by friendly

Walid Ben-Amar; Franck Missonier-Piera

2008-01-01

250

Going Green: Environmentally Friendly Schools Pay Off  

ERIC Educational Resources Information Center

The notion of campuses that are energy-efficient and ecologically friendly, and that provide a healthy, productive, comfortable environment for students and staff has been around for some time. But for many educators, green schools have remained more good intention than proven approach, a huge risk that few school leaders could--or would--take.…

LaFee, Scott

2008-01-01

251

NEEM: Network-Friendly Epidemic Multicast  

Microsoft Academic Search

Epidemic, or probabilistic, multicast protocols have emerged as a viable mech- anism to circumvent the scalability problems of reliable multicast protocols. How- ever, most existing epidemic approaches use connectionless transport protocols to exchange messages and rely on the intrinsic robustness of the epidemic dissemina- tion to mask network omissions. Unfortunately, such an approach is not network- friendly, since the epidemic

Jose Pereira; Luķs Rodrigues; M. Joćo Monteiro; Rui Carlos Oliveira; Anne-marie Kermarrec; A.-M. Kermarrec

2003-01-01

252

You've Got a Friend.  

ERIC Educational Resources Information Center

Describes the fundraising efforts of the Torrey Pines High School (California) library through the formation of a Friends of the Library group. Discusses how to form a nonprofit corporation, making the purchase of new books a priority, increasing the library's visibility, and ideas for fundraising events. (LRW)

Politzer, Linda

1999-01-01

253

Overcoming Friendly Fire: Restructuring High Schools.  

ERIC Educational Resources Information Center

Explores high school restructuring efforts under the Kentucky Education Reform Act. Issues of performance-based measures of learning and graduation requirements are discussed. Designing schools with the goal that all students succeed can overcome the friendly fire of cross-purposes in education. (SLD)

Fischetti, John; And Others

1993-01-01

254

Participants in "Friends with Benefits" Relationships  

ERIC Educational Resources Information Center

Analysis of survey data from 1013 undergraduates at a large southeastern university revealed that over half (51%) reported experience in a "friends with benefits" relationship. In comparing the background characteristics of participants with nonpartipants in a FWBR, ten statistically significant findings emerged. Findings included that…

Puentes, Jennifer; Knox, David; Zusman, Marty E.

2008-01-01

255

User`s guide and physics manual for the SCATPlus circuit code  

SciTech Connect

ScatPlus is a user friendly circuit code and an expandable library of circuit models for electrical components and devices; it can be used to predict the transient behavior in electric circuits. The heart of ScatPlus is the transient circuit solver SCAT written in 1986 by R.F. Gribble. This manual includes system requirements, physics manual, ScatPlus component library, tutorial, ScatPlus screen, menus and toolbar, ScatPlus tool bar, procedures.

Yapuncich, M.L.; Deninger, W.J.; Gribble, R.F.

1994-05-09

256

Identification of User Facility Related Publications  

SciTech Connect

Scientific user facilities provide physical resources and technical support that enable scientists to conduct experiments or simulations pertinent to their respective research. One metric for evaluating the scientific value or impact of a facility is the number of publications by users as a direct result of using that facility. Unfortunately, for a variety of reasons, capturing accurate values for this metric proves time consuming and error-prone. This work describes a new approach that leverages automated browser technology combined with text analytics to reduce the time and error involved in identifying publications related to user facilities. With this approach, scientific user facilities gain more accurate measures of their impact as well as insight into policy revisions for user access.

Patton, Robert M [ORNL; Stahl, Christopher G [ORNL; Potok, Thomas E [ORNL; Wells, Jack C [ORNL

2012-01-01

257

Usability Testing, User-Centered Design, and LibGuides Subject Guides: A Case Study  

ERIC Educational Resources Information Center

Usability testing has become a routine way for many libraries to ensure that their Web presence is user-friendly and accessible. At the same time, popular subject guide creation systems, such as LibGuides, decentralize Web content creation and put authorship into the hands of librarians who may not be trained in user-centered design principles. At…

Sonsteby, Alec; DeJonghe, Jennifer

2013-01-01

258

Incremental Learning of Tasks From User Demonstrations, Past Experiences, and Vocal Comments  

Microsoft Academic Search

Since many years the robotics community is envisioning robot assistants sharing the same environment with humans. It became obvious that they have to interact with humans and should adapt to individual user needs. Especially the high variety of tasks robot assistants will be facing requires a highly adaptive and user-friendly programming interface. One possible solution to this programming problem is

Michael Pardowitz; Steffen Knoop; Ruediger Dillmann; Raoul D. Zollner

2007-01-01

259

Influence of Learning Styles on Graphical User Interface Preferences for e-Learners  

ERIC Educational Resources Information Center

Implementing Web-based educational environment requires not only developing appropriate architectures, but also incorporating human factors considerations. User interface becomes the major channel to convey information in e-learning context: a well-designed and friendly enough interface is thus the key element in helping users to get the best…

Dedic, Velimir; Markovic, Suzana

2012-01-01

260

Spying Out Real User Preferences for Metasearch Engine Personalization  

Microsoft Academic Search

Most current metasearch engines provide uniform service to users but do not cater for the speciflc needs of individual users. To address this problem, research has been done on personalizing a metasearch engine. An interesting and practical approach is to optimize its ranking function using clickthrough data. However, it is still challenging to infer accurate user preferences from the clickthrough

Lin Deng; Xiaoyong Chai; Qingzhao Tan; Wilfred Ng; Dik Lun Lee; O. Nasraoui

261

Having Babies May Be 'Contagious' Among Long-Time Friends  

MedlinePLUS

... JavaScript. Having Babies May Be 'Contagious' Among Long-Time Friends Women tend to get pregnant soon after ... News) -- Getting pregnant may be contagious among long-time friends -- when one woman has a baby, her ...

262

You don't de-friend the dead: an analysis of grief communication by college students through Facebook profiles.  

PubMed

This research examined how various members of a social network interact with the Facebook (FB) profile page of a friend who has died. From 43 in-depth qualitative interviews, FB friends of deceased FB users maintained their FB connection with the deceased. Most participants who visited the profile found it helpful to look at pictures; a few wrote messages to the deceased as a coping mechanism. In some instances, a spouse or parent controlled the profile, which respondents universally viewed as having a negative effect on their ability to cope with their loss. PMID:24520964

Pennington, Natalie

2013-08-01

263

Feedback quality and environmentally friendly use of domestic central heating systems.  

PubMed

The study examined the influence of system-embedded feedback on user behaviour during the environmentally friendly operation of a central heating system. A PC-based simulation, called CHESS, was developed to model the critical features of a central heating system. After having received 30 min of training on the simulation task, 60 participants worked on a series of operational scenarios under different levels of system feedback. In addition to the collection of various performance measures (e.g. energy consumption, energy wastage), a range of user variables was collected (e.g. environmental concern). As hypothesized, the results showed that increased feedback resulted in improved environmentally friendly performance and, more importantly, the specific feedback indicator influenced the type of strategy used to improve human - machine system performance. A major implication is that system designers need to develop feedback indicators that are chiefly influenced by user behaviour and are largely immune to factors that are beyond the user's control (e.g. weather conditions). PMID:17457742

Sauer, J; Schmeink, C; Wastell, D G

2007-06-01

264

Identifying Less Accurately Measured Students  

Microsoft Academic Search

Abstract Some students are less accurately measured,by typical reading tests than other students. By asking teachers to identify students whose performance,on state reading tests would likely underestimate their reading skills, this study sought to learn about characteristics of less accurately measured,students while also evaluating how well teachers can make such judgments. Twenty students identified by eight teachers participated in structured

Ross Moen; Kristi Liu; Martha Thurlow; Adam Lekwa; Sarah Scullin; Kristin Hausmann

265

Analysis for an environmental friendly seedling breeding system  

NASA Astrophysics Data System (ADS)

Most seedlings of crops are produced in solar greenhouse or nursery, from which some problems about energy waste and environment pollution arise. This study aims at investigating the characteristics and effect of an environmental friendly type seedling breeding system. The results demonstrate that crops can grow with a short period and little pollution in the new seedling breeding system with total manpower controllable environment that is not influenced by geography, climate and other natural conditions. By multilayer, nonplanar seedling breeding and annual batches arrangement, utilization ratio of unit area land and seedlings yield can be improved for several times and even more than 10 times. Conclusions can be obtained from the tomato seedling breeding experiments: (1) each growth index of tomato seedlings that are under the conditions of 291 ?mol/m 2 s artificial illumination intensity is remarkably better than those produced in greenhouse with natural lights. (2) The environment of the seedling breeding system can be accurately controlled. The segmented temperature changed management can be applied according to the photosynthetic characteristics of plants, and not affected by the outside environment, which makes each growth index of tomato seedling constant in different seasons. The seedlings thus grow strong and can achieve the level of commodity seedlings after 20-30 days. (3) The temperature and humidity environment of the seedling breeding system can be accurately controlled according to plants growth demands.

Qu, Y. H.; Wei, X. M.; Hou, Y. F.; Chen, B.; Chen, G. Q.; Lin, C.

2009-04-01

266

What Are Friends For? Students' Expectations of the Friendship Encounter.  

ERIC Educational Resources Information Center

Examines factors contributing to a person's desire to talk to a friend about personal problems. Results suggest that students value genuine, accepting, confrontive friends whom they can trust. In contrast, the expectancies that counselors are directive, expert, tolerant, and trustworthy are higher than those for the friend. (Author)

Parham, William D.; Tinsley, Howard E.A.

1980-01-01

267

More Colleges Are Adding Family-Friendly Benefits  

ERIC Educational Resources Information Center

Results of a new survey of family-friendly benefits by the Center for the Education of Women at the University of Michigan at Ann Arbor show that stopping the tenure clock has become the most common family-friendly benefit in higher education, following paid maternity leave. Other family-friendly policies that top the list in academe allow…

Wilson, Robin

2008-01-01

268

Friends of Survivors: The Community Impact of Unwanted Sexual Experiences  

ERIC Educational Resources Information Center

Since sexual assault survivors are most likely to disclose their experiences to a friend; prevention efforts increasingly focus on friends as informal helpers. The current study examined friends' perceptions of the disclosure experience. Undergraduates (N = 1,241) at the University of New Hampshire completed a shortened version of the Ahrens and…

Banyard, Victoria L.; Moynihan, Mary M.; Walsh, Wendy A.; Cohn, Ellen S.; Ward, Sally

2010-01-01

269

Similarities between Friends and Nonfriends in Middle Childhood.  

ERIC Educational Resources Information Center

Assessed similarities between 192 target children and their friends and nonfriends. Found that children and friends were more similar to one another than nonfriends across the dataset. Friendship similarities were greater in antisocial behavior than in other domains. Similarities between friends in sociometric status and size of the friendship…

Haselager, Gerbert J. T.; Hartup, Willard W.; van Lieshout, Cornelis F. M.; Riksen-Walraven, J. Marianne A.

1998-01-01

270

The Role of Competence in Children's Creation of Imaginary Friends.  

ERIC Educational Resources Information Center

The function of children's imaginary friends was investigated from the perspective of perceived competence. Teachers judged children with imaginary friends to be less competent and socially accepted by peers than other children. Children's descriptions of themselves and their imaginary friends revealed significant gender differences in the types…

Harter, Susan; Chao, Christine

1992-01-01

271

Associations between friends' disordered eating and muscle-enhancing behaviors  

PubMed Central

Dieting, unhealthy weight control and muscle-enhancing behaviors are common among adolescents: friends are a probable source of influence on these behaviors. The present study uses data provided by nominated friends to examine associations between friends' disordered eating and muscle-enhancing behaviors and participants' own behaviors in a diverse sample of American youth. Male and female adolescents (mean age = 14.4) completed surveys and identified their friends from a class roster; friends' survey data were then linked to each participant. Participants (N = 2126) who had at least one nominated friend were included in the analytic sample. Independent variables were created using the same weight control and muscle-enhancing behaviors reported by nominated friends, and were used in logistic regression models to test associations between participants' and their friends' behaviors, stratified by gender. Results indicated that dieting, disordered eating and muscle-enhancing behaviors were common in this sample, and selected friends' behaviors were associated with the same behaviors in participants. For example, girls whose friends reported extreme weight control behaviors had significantly greater odds of using these behaviors than girls whose friends did not report these same behaviors (OR = 2.39). This research suggests that friends' weight- and shape-related behaviors are a feature of social relationships, and is the first report demonstrating these associations for muscle-enhancing behaviors. Capitalizing on the social element may be important to the development of increasingly effective intervention and prevention programs.

Eisenberg, Marla E.; Wall, Melanie; Shim, Jin Joo; Bruening, Meg; Loth, Katie; Neumark-Sztainer, Dianne

2012-01-01

272

Finding Close Friends on the Internet  

Microsoft Academic Search

We consider the problem of finding nearby application-peers(close friends) over the Internet. We focus on unicast-only solutions and introduce a new scheme — Beaconing— for finding peers that are near. Our scheme uses distance measurement points (called bea- cons) and can be implemented entirely in the application-layer without investing in large infrastructure changes. We present an extensive evaluation of Beaconing

Christopher Kommareddy; Narendar Shankar; Bobby Bhattacharjee

2001-01-01

273

Robot-friendly connector. [space truss structures  

NASA Technical Reports Server (NTRS)

Robot friendly connectors, which, in one aspect, are truss joints with two parts, a receptacle and a joint, are presented. The joints have a head which is loosely inserted into the receptacle and is then tightened and aligned. In one aspect, the head is a rounded hammerhead which initially is enclosed in the receptacle with sloppy fit provided by the shape, size, and configuration of surfaces on the head and on the receptacle.

Parma, George F. (inventor); Vandeberghe, Mark H. (inventor); Ruiz, Steve C. (inventor)

1993-01-01

274

Soil-friendly off-road suspension  

Microsoft Academic Search

The article investigates the potential of controlled vehicle suspension for off-road vehicles. The primary question is whether the controlled vehicle suspension can reduce the deformation of the deformable off-road (soil) and can become a soil-friendly suspension. The article represents the preliminary study of this problem, in the sense that the realistic but simple models for the vehicle, the tyre—off-road contact,

M. Valasek; J. Sveda; Z. Sika

2006-01-01

275

Design of pedestrian friendly vehicle bumper  

Microsoft Academic Search

Car-pedestrian accidents take thousands of lives worldwide annually. Therefore, pedestrian protection is an important issue\\u000a in traffic safety. How to consider a pedestrian friendliness vehicle and then propose pedestrian protection methods are urgent\\u000a works for minimizing pedestrian injury. For designing a pedestrian friendly vehicle bumper, this study adopts the European\\u000a Enhanced Vehicle-safety Committee\\/ Working Group 17 (EEVC\\/WG17) regulations of legform

Tso-Liang Teng; Van-Luc Ngo; Trong-Hai Nguyen

2010-01-01

276

Development of an intelligent user interface for NASA's scientific databases  

SciTech Connect

The National Space Science Data Center (NSSDC) has initiated an Intelligent Data Management (IDM) research effort which has as one of its components, the development of an Intelligent User Interface (IUI). The intent of the IUI effort is to develop a friendly and intelligent user interface service that is based on expert systems and natural language processing technologies. This paper presents the design concepts, development approach and evaluation of performance of a prototype Intelligent User Interface Subsystem (IUIS) supporting an operational database. 16 references.

Campbell, W.J.; Roelofs, L.H. (NASA, Goddard Space Flight Center, Greenbelt, MD; Computer Technology Associates, Inc. McLean, VA)

1986-01-01

277

JEDI Marine and Hydrokinetic Model: User Reference Guide  

SciTech Connect

The Jobs and Economic Development Impact Model (JEDI) for Marine and Hydrokinetics (MHK) is a user-friendly spreadsheet-based tool designed to demonstrate the economic impacts associated with developing and operating MHK power systems in the United States. The JEDI MHK User Reference Guide was developed to assist users in using and understanding the model. This guide provides information on the model's underlying methodology, as well as the sources and parameters used to develop the cost data utilized in the model. This guide also provides basic instruction on model add-in features, operation of the model, and a discussion of how the results should be interpreted.

Goldberg, M.; Previsic, M.

2011-04-01

278

Sparse and accurate high resolution SAR imaging  

NASA Astrophysics Data System (ADS)

We investigate the usage of an adaptive method, the Iterative Adaptive Approach (IAA), in combination with a maximum a posteriori (MAP) estimate to reconstruct high resolution SAR images that are both sparse and accurate. IAA is a nonparametric weighted least squares algorithm that is robust and user parameter-free. IAA has been shown to reconstruct SAR images with excellent side lobes suppression and high resolution enhancement. We first reconstruct the SAR images using IAA, and then we enforce sparsity by using MAP with a sparsity inducing prior. By coupling these two methods, we can produce a sparse and accurate high resolution image that are conducive for feature extractions and target classification applications. In addition, we show how IAA can be made computationally efficient without sacrificing accuracies, a desirable property for SAR applications where the size of the problems is quite large. We demonstrate the success of our approach using the Air Force Research Lab's "Gotcha Volumetric SAR Data Set Version 1.0" challenge dataset. Via the widely used FFT, individual vehicles contained in the scene are barely recognizable due to the poor resolution and high side lobe nature of FFT. However with our approach clear edges, boundaries, and textures of the vehicles are obtained.

Vu, Duc; Zhao, Kexin; Rowe, William; Li, Jian

2012-05-01

279

Age-friendly nursing interventions in the management of older people in emergency departments.  

PubMed

Older people are high users of emergency department services, and on presentation, are often acutely ill. Nurses working in the emergency department are at the forefront of dealing with these challenges, by providing care that is specifically tailored to meet the needs of the older population and reducing the risks of adverse health outcomes during their stay in the emergency department. The ideal age-friendly emergency department environment supports the strengths and abilities of the older person, protects them against harm, and empowers individuals and their carers to be actively involved in decision-making. This information sheet focuses on the best-available evidence on age-friendly nursing interventions in the management of older patients during their stay in emergency department. PMID:22640024

2012-06-01

280

Xwake 1.0 user`s manual  

SciTech Connect

Xwake is a user friendly Finite Difference Time Domain (FDTD) code for wake potential and impedance calculations of rotationally symmetric structures. Geometry boundaries are automatically meshed, or modeled, by a choice of either of two approximations, the typical {open_quotes}stepped edge{close_quotes} modeling, or the new {open_quotes}contour{close_quotes} modeling. Contouring means geometry boundaries described with curves and angles are not distorted to follow the rectangular grid; rather, the grid is adjusted to follow the contour of the geometry boundaries. It offers computer run time savings for large problems or intricate geometries for a given mesh compared with stepped edge modeling. Using stepped approximations with Xwake, on the other hand, one is able to model materials of any linear media type. Ultimately, three solutions are computed, wake potential versus wake length, wake spectrum versus frequency - a Fourier transform (FFT) of the wake potential, and wake impedance versus frequency. Xwake is an OSF/Motif application providing a graphical user interface (GUI) for ease of use. It is written in ANSI C for portability and currently runs on UNIX platforms.

Saewert, G.; Jurgens, T.; Harfoush, F.

1994-07-01

281

The Tacit Dimension of User Tasks: Elicitation and Contextual Representation  

Microsoft Academic Search

Traditional task-elicitation techniques provide prepared structures for acquiring and representing knowledge about user tasks.\\u000a As different users might perceive work tasks quite differently, normative elicitation and representation schemes do not necessarily\\u000a lead to accurate support of individual users. If the individual perception of tasks should guide the development of user interfaces\\u000a personal constructs have to be taken into account. They

Jeannette Hemmecke; Chris Stary

2006-01-01

282

miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades  

PubMed Central

microRNAs (miRNAs) are a large class of small non-coding RNAs which post-transcriptionally regulate the expression of a large fraction of all animal genes and are important in a wide range of biological processes. Recent advances in high-throughput sequencing allow miRNA detection at unprecedented sensitivity, but the computational task of accurately identifying the miRNAs in the background of sequenced RNAs remains challenging. For this purpose, we have designed miRDeep2, a substantially improved algorithm which identifies canonical and non-canonical miRNAs such as those derived from transposable elements and informs on high-confidence candidates that are detected in multiple independent samples. Analyzing data from seven animal species representing the major animal clades, miRDeep2 identified miRNAs with an accuracy of 98.6–99.9% and reported hundreds of novel miRNAs. To test the accuracy of miRDeep2, we knocked down the miRNA biogenesis pathway in a human cell line and sequenced small RNAs before and after. The vast majority of the >100 novel miRNAs expressed in this cell line were indeed specifically downregulated, validating most miRDeep2 predictions. Last, a new miRNA expression profiling routine, low time and memory usage and user-friendly interactive graphic output can make miRDeep2 useful to a wide range of researchers.

Friedlander, Marc R.; Mackowiak, Sebastian D.; Li, Na; Chen, Wei; Rajewsky, Nikolaus

2012-01-01

283

Facebook friends with (health) benefits? Exploring social network site use and perceptions of social support, stress, and well-being.  

PubMed

There is clear evidence that interpersonal social support impacts stress levels and, in turn, degree of physical illness and psychological well-being. This study examines whether mediated social networks serve the same palliative function. A survey of 401 undergraduate Facebook users revealed that, as predicted, number of Facebook friends associated with stronger perceptions of social support, which in turn associated with reduced stress, and in turn less physical illness and greater well-being. This effect was minimized when interpersonal network size was taken into consideration. However, for those who have experienced many objective life stressors, the number of Facebook friends emerged as the stronger predictor of perceived social support. The "more-friends-the-better" heuristic is proposed as the most likely explanation for these findings. PMID:23790356

Nabi, Robin L; Prestin, Abby; So, Jiyeon

2013-10-01

284

The development of an intelligent user interface for NASA's scientific databases  

NASA Technical Reports Server (NTRS)

The National Space Science Data Center (NSSDC) has initiated an Intelligent Data Management (IDM) research effort which has as one of its components, the development of an Intelligent User Interface (IUI). The intent of the IUI effort is to develop a friendly and intelligent user interface service that is based on expert systems and natural language processing technologies. This paper presents the design concepts, development approach and evaluation of performance of a prototype Intelligent User Interface Subsystem (IUIS) supporting an operational database.

Campbell, William J.; Roelofs, Larry H.

1986-01-01

285

Accurate Replication in Genetic Programming  

Microsoft Academic Search

Abstract One characteristic tendency of genetic program - ming is the production of considerably larger trees than expected It has been suggested that this is related to the ability of individuals to replicate ac - curately In this paper we present theoretical anal - ysis which shows that, for certain specific cases, the pressure for accurate replication induces an increase

Nicholas Freitag Mcphee; Justin Darwin Miller

1995-01-01

286

Modeling the user in intelligent user interfaces  

SciTech Connect

A methodology for explicitly defining a model of a program's users and for evaluating the effectiveness of the user interface is presented. The development of an explicit user model will reduce user costs by both reducing the cost of software development and increasing user productivity. The components of the methodology are described, and an example of using the methodology in the development of an expert consultant system is given. The methodology can be useful in preliminary design and testing of such interactive software as electronic mail, information retrieval systems, editors, and management information systems.

Stoddard, M.L.; Douglass, R.J.

1983-01-01

287

Microbiota, immunoregulatory old friends and psychiatric disorders.  

PubMed

Regulation of the immune system is an important function of the gut microbiota. Increasing evidence suggests that modern living conditions cause the gut microbiota to deviate from the form it took during human evolution. Contributing factors include loss of helminth infections, encountering less microbial biodiversity, and modulation of the microbiota composition by diet and antibiotic use. Thus the gut microbiota is a major mediator of the hygiene hypothesis (or as we prefer, "Old Friends" mechanism), which describes the role of organisms with which we co-evolved, and that needed to be tolerated, as crucial inducers of immunoregulation. At least partly as a consequence of reduced exposure to immunoregulatory Old Friends, many but not all of which resided in the gut, high-income countries are undergoing large increases in a wide range of chronic inflammatory disorders including allergies, autoimmunity and inflammatory bowel diseases. Depression, anxiety and reduced stress resilience are comorbid with these conditions, or can occur in individuals with persistently raised circulating levels of biomarkers of inflammation in the absence of clinically apparent peripheral inflammatory disease. Moreover poorly regulated inflammation during pregnancy might contribute to brain developmental abnormalities that underlie some cases of autism spectrum disorders and schizophrenia. In this chapter we explain how the gut microbiota drives immunoregulation, how faulty immunoregulation and inflammation predispose to psychiatric disease, and how psychological stress drives further inflammation via pathways that involve the gut and microbiota. We also outline how this two-way relationship between the brain and inflammation implicates the microbiota, Old Friends and immunoregulation in the control of stress resilience. PMID:24997041

Rook, Graham A W; Raison, Charles L; Lowry, Christopher A

2014-01-01

288

Making radiosity usable: automatic preprocessing and meshing techniques for the generation of accurate radiosity solutions  

Microsoft Academic Search

Generating accurate radiosity solutions of real world environments is user-intensive and requires significant knowledge of the method. As a result, few end-users such as architects and designers use it. The output of most commercial modeling packages must be substantially \\

Daniel R. Baum; Stephen Mann; Kevin P. Smith; James M. Winget

1991-01-01

289

A customer-friendly Space Station  

NASA Technical Reports Server (NTRS)

This paper discusses the relationship of customers to the Space Station Program currently being defined by NASA. Emphasis is on definition of the Program such that the Space Station will be conducive to use by customers, that is by people who utilize the services provided by the Space Station and its associated platforms and vehicles. Potential types of customers are identified. Scenarios are developed for ways in which different types of customers can utilize the Space Station. Both management and technical issues involved in making the Station 'customer friendly' are discussed.

Pivirotto, D. S.

1984-01-01

290

Wakuzulu: Friends of the Colobus Trust  

NSDL National Science Digital Library

Wakuzulu: Friends of the Colobus Trust is a not-for-profit organization based in Kenya dedicated to the "conservation, preservation, and protection of primates, in particular the Angolan Black and White Colobus monkey." Wakuzulu's extensive homepage features the latest updates on the Colobus population in the Diani area, as well as detailed information about the organization's projects and initiatives. First time visitors may wish to check out the section titled Diani's Primates, which offers an excellent introduction to Colobus monkeys and other species in the area.

291

Bayesian Auctions with Friends and Foes  

NASA Astrophysics Data System (ADS)

We study auctions whose bidders are embedded in a social or economic network. As a result, even bidders who do not win the auction themselves might derive utility from the auction, namely, when a friend wins. On the other hand, when an enemy or competitor wins, a bidder might derive negative utility. Such spite and altruism will alter the bidding strategies. A simple and natural model for bidders’ utilities in these settings posits that the utility of a losing bidder i as a result of bidder j winning is a constant (positive or negative) fraction of bidder j’s utility.

Chen, Po-An; Kempe, David

292

Media and breastfeeding: friend or foe?  

PubMed

The mass media have the potential to be powerful friends or foes in promoting breastfeeding. The media could help by putting the issue of breastfeeding on policy agendas and by framing breastfeeding as healthy and normative for baby and mother. Currently, however, it looks as if the media are more often contributing to perceptions that breastfeeding is difficult for mothers and potentially dangerous for babies. This paper presents a brief overview of research on the media and breastfeeding, some insights into the market forces and human psychological factors that may play into media representations of breastfeeding, and strategies to help breastfeeding advocates work more effectively with the media. PMID:18680582

Brown, Jane D; Peuchaud, Sheila Rose

2008-01-01

293

Time-Accurate Computational Simulation  

NASA Technical Reports Server (NTRS)

Time accurate CFD may offer a faster approach to S&C aerodynamic database population than the conventional point by point steady state CFD. We would directly simulate -, -sweeps or other configuration movements typically of measurement sequence in wind tunnels. A second objective is to demonstrate potential applications to assessment of S&C dynamic derivatives by simulating vehicle motions such as free to roll, and nonlinearity such as the trends of aerodynamic forces near CL-max or flow hysteresis.

Pao, S. Paul; Buning, Pieter G.

2004-01-01

294

From accurate machining towards accurate measurements with MICROSCOPE  

NASA Astrophysics Data System (ADS)

Observing any violation of the Equivalence Principle at a level as low as 10 -15 needs both a very soft and stable environment and a very accurate instrument The MICROSCOPE space laboratory allows testing of the universality of free fall with two masses made of a Platinum Rhodium alloy and a Titanium alloy in a 10 pico-g environment The two test-masses are accurately controlled by electrostatic forces to follow a common geodesic within a CNES drag-free microsatellite Accurate centring and alignment of the test-masses is mandatory to prevent any artefact signal due to the Earth s gravity gradient or any on-board gravity gradient To this purpose the MICROSCOPE instrument called Twin-Space Accelerometer for Gravitation Experimentation T-SAGE has been designed to minimise the gravity gradient disturbances A laboratory model and a first representative model for vibration tests have been produced integrated and tested These models have allowed verification of the manufacturing and integration processes and of their accuracy which gives a first budget for the expected centring and alignment of the flight-models This paper describes the micro-meter machining and integration challenges of T-SAGE and their impact on the instrument performance In particular the shape of the test-mass has an effect on the differential accelerometer output due to the gravity gradient and also on the instrument capacitive position output used for the electrostatic servo-loop First results obtained with the fully integrated models are also presented to assess the

Rodrigues, M.; Touboul, P.; Chhun, R.; Hudson, D.; Foulon, B.; Flinoise, P.; Bodoville, G.; Lebat, V.

295

Organic Foods: Do Eco-Friendly Attitudes Predict Eco-Friendly Behaviors?  

ERIC Educational Resources Information Center

Objective: The purpose of this study was to determine whether student awareness and attitudes about organic foods would predict their behaviors with regard to organic food consumption and other healthy lifestyle practices. A secondary purpose was to determine whether attitudes about similar eco-friendly practices would result in socially conscious…

Dahm, Molly J.; Samonte, Aurelia V.; Shows, Amy R.

2009-01-01

296

The User Experience  

ERIC Educational Resources Information Center

User experience (UX) is about arranging the elements of a product or service to optimize how people will interact with it. In this article, the author talks about the importance of user experience and discusses the design of user experiences in libraries. He first looks at what UX is. Then he describes three kinds of user experience design: (1)…

Schmidt, Aaron

2010-01-01

297

Convergent spray process for environmentally friendly coatings  

NASA Technical Reports Server (NTRS)

Conventional spray application processes have poor transfer efficiencies, resulting in an exorbitant loss in materials, solvents, and time. Also, with ever tightening Environmental Protection Agency (EPA) regulations and Occupational Safety and Health Administration requirements, the low transfer efficiencies have a significant impact on the quantities of materials and solvents that are released into the environment. High solids spray processes are also limited by material viscosities, thus requiring many passes over the surface to achieve a thickness in the 0.125 -inch range. This results in high application costs and a negative impact on the environment. Until recently, requirements for a 100 percent solid sprayable, environmentally friendly, lightweight thermal protection system that can be applied in a thick (greater than 0.125 inch) single-pass operation exceeded the capability of existing systems. Such coatings must be applied by hand lay-up techniques, especially for thermal and/or fire protection systems. The current formulation of these coatings has presented many problems such as worker safety, environmental hazards, waste, high cost, and application constraints. A system which can apply coatings without using hazardous materials would alleviate many of these problems. Potential applications include the aerospace thermal protective specialty coatings, chemical and petroleum industries that require fire-protection coatings that resist impact, chemicals, and weather. These markets can be penetrated by offering customized coatings applied by automated processes that are environmentally friendly.

Scarpa, Jack

1995-01-01

298

Cold Friends of Hot Jupiters: NIRSPEC Survey  

NASA Astrophysics Data System (ADS)

Previous surveys have shown that half of all stars occur in binary systems. Although most exoplanet surveys exclude systems with known binary companions, it is likely that many known planetary systems contain distant, low-mass stellar companions that went unnoticed in the initial survey selection. Such companions may have important effects on the formation and migration of planets (and especially hot Jupiters) around the primary star via three-body interactions such as Kozai-driven migration. The Cold Friends project uses three observing techniques to make a robust determination of the occurrence rate of exoplanets in binary systems: radial velocity monitoring, adaptive optics imaging (see presentation on the AO Survey by H. Ngo et al.), and near-infrared spectroscopy. In this presentation, we focus on the results of the spectroscopy portion of the Cold Friends project. Using NIRSPEC at Keck Observatory, we have obtained high-resolution spectra of roughly fifty exoplanet-hosting stars near 2.3 microns, where low-mass companions will show deep CO absorption features superimposed on the primary stellar spectrum. This method allows for the detection of binary companions located within 50 to 200 AU of the host star. At this location, such a binary companion could conceivably influence the formation and migration of exoplanets orbiting the main star. We describe our method for removing the signal due to the main-sequence FGK host stars and searching for the distinctive spectral features of a low-mass stellar companion.

Piskorz, Danielle; Knutson, H. A.; Muirhead, P. S.; Batygin, K.; Crepp, J. R.; Hinkley, S.; Howard, A. W.; Johnson, J. A.; Morton, T. D.

2013-10-01

299

Roll forming of eco-friendly stud  

NASA Astrophysics Data System (ADS)

In order to manufacture an eco-friendly stud, the sheared pattern is designed by the Taguchi method and expanded by the side rolls. The seven geometrical shape of sheared pattern are considered in the structural and thermal analyses to select the best functional one in terms of the durability and fire resistance of dry wall. For optimizing the size of the sheared pattern chosen, the L9 orthogonal array and smaller-the-better characteristics of the Taguchi method are used. As the roll gap causes forming defects when the upper-and-lower roll type is adopted for expanding the sheared pattern, the side roll type is introduced. The stress and strain distributions obtained by the FEM simulation of roll-forming processes are utilized for the design of expanding process. The expanding process by side rolls shortens the length of expanding process and minimizes the cost of dies. Furthermore, the stud manufactured by expanding the sheared pattern of the web is an eco-friend because of the scrapless roll-forming process. In addition, compared to the conventionally roll-formed stud, the material cost is lessened about 13.6% and the weight is lightened about 15.5%.

Keum, Y. T.; Lee, S. Y.; Lee, T. H.; Sim, J. K.

2013-12-01

300

Women's HIV disclosure to family and friends.  

PubMed

Previous researchers have documented rates of HIV disclosure to family at discrete time periods, yet none have taken a dynamic approach to this phenomenon. The purpose of this study is to take the next step and provide a retrospective comparison of rates of women's HIV disclosure to family and friends over a 15-year time span. Of particular interest are the possible influences of social network and relationship characteristics on the time-to-disclosure of serostatus. Time-to-disclosure was analyzed from data provided by 125 HIV-positive women. Participants were primarily married or dating (42%), unemployed (79.2%), African American (68%) women with a high school diploma or less (54.4%). Length of time since diagnosis ranged from 1 month to over 19 years (M=7.1 years). Results pointed to statistically significant differences in time-to-disclosure between family, friends, and sexual partners. Additionally, females and persons with whom the participant had more frequent contact were more likely to be disclosed to, regardless of the type of relationship. The results of this study underscore possible challenges with existing studies which have employed point prevalence designs, and point to new methods which could be helpful in family research. PMID:22313348

Serovich, Julianne Maria; Craft, Shonda M; Reed, Sandra J

2012-04-01

301

Narcissism and discrepancy between self and friends' perceptions of personality.  

PubMed

Most research on narcissism and person perception has used strangers as perceivers. However, research has demonstrated that strangers' ratings are influenced by narcissists' stylish appearance (Back, Schmukle, & Egloff, 2010). In the present study, we recruited participants and their close friends, individuals whose close relationship should immunize them to participants' superficial appearance cues. We investigated the relation between narcissism and personality ratings by self and friends. Participants (N?=?66; 38 women; Mage ?=?20.83 years) completed the Narcissistic Personality Inventory (Raskin & Terry, 1988) and described their personality on the 100-item California Adult Q-Sort (CAQ; Block, 2008). Participants' personality was also described on the CAQ by close friends. The "optimally adjusted individual" prototype was used to summarize participant and friend personality ratings (Block, 2008). Participants with high narcissism scores were ascribed higher optimal adjustment by self than by friends. Narcissistic individuals' self-ratings were extremely positive and more favorable than friends' ratings of them. PMID:23799917

Park, Sun W; Colvin, C Randall

2014-08-01

302

ETPRE User's Manual Version 2. 00  

SciTech Connect

ETPRE is a preprocessor for the Event Progression Analysis Code EVNTRE. It reads an input file of event definitions and writes the lengthy EVNTRE code input files. ETPRE's advantage is that it eliminates the error-prone task of manually creating or revising these files since their formats are quite elaborate. The user-friendly format of ETPRE differs from the EVNTRE code format in that questions, branch references, and other event tree components are defined symbolically instead of numerically. When ETPRE is executed, these symbols are converted to their numeric equivalents and written to the output files using format defined in the EVNTRE Reference Manual. Revisions to event tree models are simplified by allowing the user to edit the symbolic format and rerun the preprocessor, since questions, branch references, and other symbols are automatically resequenced to their new values with each execution.

Roginski, R.J.

1993-02-01

303

Exploring the Social Implications of Location Based Social Networking: An Inquiry into the Perceived Positive and Negative Impacts of Using LBSN between Friends  

Microsoft Academic Search

Location based social networking (LBSN) applications are part of a new suite of emerging social networking tools that run on the Web 2.0 platform. LBSN is the convergence between location based services (LBS) and online social networking (OSN). LBSN applications offer users the ability to look up the location of another “friend” remotely using a smart phone, desktop or other

Sarah Jean Fusco; Katina Michael; M. G. Michael; Roba Abbas

2010-01-01

304

Physical Activity and Screen Time in Adolescents and Their Friends  

PubMed Central

Background Little is known about the actual physical activity and screen time behaviors of an adolescent’s friends relative to the individual’s behavior. Purpose To determine the associations between an adolescent’s physical activity and screen time and his/her nominated friends’ physical activity and screen time. Methods Data were obtained from EAT 2010 (Eating and Activity Among Teens), a large cross-sectional study (n=2126) conducted in 20 middle schools and high schools in Minneapolis/St. Paul MN during the 2009–2010 academic year and analyzed during 2011. Each participant nominated up to six friends from a school roster, and data from those friends were obtained as part of the school-based data collection procedures. Physical activity and screen time were assessed with previously used and validated questionnaires. Generalized estimating equation models, stratified by gender, were used to assess associations between adolescents’ physical activity and screen time and their friends’ physical activity and screen time. Results Physical activity for female adolescents was associated with their male and female friends’ physical activity, including their male and female best friends (all p<0.05). Males’ physical activity was associated with their female friends’ physical activity (p<0.03). Females’ screen time was associated with their male and female friends’ screen time (p?0.03), but not with that of their best friends. Males’ screen time was associated with only their female friends’ screen time (p=0.04). Conclusions The consistent association between female adolescents’ physical activity and their friends’ physical activity indicates a need to include peer effects on adolescent female physical activity in future intervention work.

Sirard, John R.; Bruening, Meg; Wall, Melanie M.; Eisenberg, Marla E.; Kim, Sun K.; Neumark-Sztainer, Dianne

2012-01-01

305

Time scales, their users, and leap seconds  

Microsoft Academic Search

Numerous time scales exist to address specific user requirements. Accurate dynamical time scales (barycentric, geocentric and terrestrial) have been developed based on the theory of relativity. A family of time scales has been developed based on the rotation of the Earth that includes Universal Time (specifically UT1), which serves as the traditional astronomical basis of civil time. International Atomic Time

P. Kenneth Seidelmann; John H. Seago

2011-01-01

306

[Fostering a breastfeeding-friendly workplace].  

PubMed

Creating supportive environments that encourage mothers to breastfeed their children has emerged in recent years as a key health issue for women and children. Taiwan has a large and still growing number of new mothers in the workplace. Early postpartum return to work and inconvenient workplace conditions often discourage women from breastfeeding or cause early discontinuation. This study describes the current status of worksite breastfeeding-friendly policies in Taiwan and selected other countries and assesses the effects of work-related factors on working mother breastfeeding behavior. Although maternity leave has been positively correlated with breastfeeding duration, maternity leave in Taiwan remains significantly shorter than in other countries. Flexible working conditions, the provision of lactation rooms, and support from colleagues are critical components of promoting breastfeeding in the workplace. PMID:23386521

Chen, Yi-Chun; Kuo, Shu-Chen

2013-02-01

307

Microbial 'Old Friends', immunoregulation and stress resilience  

PubMed Central

Chronic inflammatory diseases (autoimmunity, allergy and inflammatory bowel diseases) are increasing in prevalence in urban communities in high-income countries. One important factor is reduced exposure to immunoregulation-inducing macro- and microorganisms and microbiota that accompanied mammalian evolution (the hygiene hypothesis or ‘Old Friends’ mechanism). Reduced exposure to these organisms predisposes to poor regulation of inflammation. But inflammation is equally relevant to psychiatric disorders. Inflammatory mediators modulate brain development, cognition and mood, and accompany low socioeconomic status and some cases of depression in developed countries. The risk of all these conditions (chronic inflammatory and psychiatric) is increased in urban versus rural communities, and increased in immigrants, particularly if they move from a low- to a high-income country during infancy, and often the prevalence increases further in second generation immigrants, suggesting that critical exposures modulating disease risk occur during pregnancy and infancy. Diminished exposure to immunoregulation-inducing Old Friends in the perinatal period may enhance the consequences of psychosocial stressors, which induce increased levels of inflammatory mediators, modulate the microbiota and increase the risk for developing all known psychiatric conditions. In later life, the detrimental effects of psychosocial stressors may be exaggerated when the stress occurs against a background of reduced immunoregulation, so that more inflammation (and therefore more psychiatric symptoms) result from any given level of psychosocial stress. This interaction between immunoregulatory deficits and psychosocial stressors may lead to reduced stress resilience in modern urban communities. This concept suggests novel interpretations of recent epidemiology, and novel approaches to the increasing burden of psychiatric disease.

Rook, Graham A. W.; Lowry, Christopher A.; Raison, Charles L.

2013-01-01

308

Predict amine solution properties accurately  

SciTech Connect

Improved process design begins with using accurate physical property data. Especially in the preliminary design stage, physical property data such as density viscosity, thermal conductivity and specific heat can affect the overall performance of absorbers, heat exchangers, reboilers and pump. These properties can also influence temperature profiles in heat transfer equipment and thus control or affect the rate of amine breakdown. Aqueous-amine solution physical property data are available in graphical form. However, it is not convenient to use with computer-based calculations. Developed equations allow improved correlations of derived physical property estimates with published data. Expressions are given which can be used to estimate physical properties of methyldiethanolamine (MDEA), monoethanolamine (MEA) and diglycolamine (DGA) solutions.

Cheng, S.; Meisen, A. [Univ. of British Columbia, Vancouver, British Columbia (Canada); Chakma, A. [Univ. of Calgary, Alberta (Canada)

1996-02-01

309

Preparation and characterisation of user-friendly PMMA microcapsules for consumer care  

NASA Astrophysics Data System (ADS)

A flat membrane combined with a mechanical stirrer has been used to prepare poly(methyl methacrylate) (PMMA) microcapsules containing an oil-based active ingredient. A florescence dye pyrromethene 546 was added in the liquid core in order to measure the shell thickness of microcapsules using confocal laser scanning microscopy under a fluorescence condition. The size distribution of the formed microcapsules was measured by a static light scattering (SLS) technique. The mechanical properties of the microcapsules were studied using a micromanipulation technique based on compression of single microcapsules between two parallel surfaces and finite element modelling (FEM).

Pan, Xuemiao; Mercade-prieto, Ruben; York, David; Preece, Jon A.; Zhang, Zhibing

2013-06-01

310

User-Friendly Tool for Evaluationg the Thermal Response of High Power Battery Packaging Alternatives.  

National Technical Information Service (NTIS)

Latest generation of high power battery cells are often comprised of multiple alternating layers of anode, cathode, separator and electrolyte. Macroscopically, battery cores represent an orthotropic material subject to a time variant heat source. Safety a...

G. Frazier J. Mendoza S. Jones S. Zanardelli

2011-01-01

311

Three Applications of Automated Test Assembly within a User-Friendly Modeling Environment  

ERIC Educational Resources Information Center

While linear programming is a common tool in business and industry, there have not been many applications in educational assessment and only a handful of individuals have been actively involved in conducting psychometric research in this area. Perhaps this is due, at least in part, to the complexity of existing software packages. This article…

Cor, Ken; Alves, Cecilia; Gierl, Mark

2009-01-01

312

User-friendly web mapping: lessons from a citizen science website  

Microsoft Academic Search

Citizen science websites are emerging as a common way for volunteers to collect and report geographic ecological data. Engaging the public in citizen science is challenging and, when involving online participation, data entry, and map use, becomes even more daunting. Given these new challenges, citizen science websites must be easy to use, result in positive overall satisfaction for many different

Greg Newman; Don Zimmerman; Alycia Crall; Melinda Laituri; Jim Graham; Linda Stapel

2010-01-01

313

Identifying and Implementing Educational Practices Supported by Rigorous Evidence: A User Friendly Guide.  

National Technical Information Service (NTIS)

The field of K-12 education contains a vast array of educational interventions - such as reading and math curricula, schoolwide reform programs, after-school programs, and new educational technologies - that claim to be able to improve educational outcome...

2003-01-01

314

LibGA: a user-friendly workbench for order-based genetic algorithm research  

Microsoft Academic Search

Over the years there haa been several packages developed that provide a workbench for genetic algorithm (GA) research. Most of these packages use the generational model inspired by GEN ESIS. A few have adopted the steady-state model used in Genitor. Unfortunately, they have some deficiencies when working with orderhsed problems such as packing, routing, and scheduling. This paper describes LibGA,

Arthur L. Corcoran; Roger L. Wainwright

1993-01-01

315

Low-Cost, User-Friendly, Rapid Analysis of Dynamic Data System Established  

NASA Technical Reports Server (NTRS)

An issue of primary importance to the development of new jet and certain other airbreathing combined-cycle powered aircraft is the advancement of airframe-integrated propulsion technologies. Namely, engine inlets and their systems and subsystems are required to capture, convert, and deliver the atmospheric airflow demanded by such engines across their operating envelope in a form that can be used to provide efficient, stable thrust. This must be done while also minimizing aircraft drag and weight. Revolutionary inlet designs aided by new technologies are needed to enable new missions. An unwanted byproduct of pursuing these inlet technologies is increased time-variant airflow distortion. Such distortions reduce propulsion system stability, performance, operability, and life. To countermand these limitations and fully evaluate the resulting configurations, best practices dictate that this distortion be experimentally measured at large scale and analyzed. The required measurements consist of those made by an array of high-response pressure transducers located in the flow field at the aerodynamic interface plane (AIP) between the inlet and engine. Although the acquisition of the necessary pitot-pressure time histories is relatively straight-forward, until recent years, the analysis has proved to be very time-consuming, tedious, and expensive. To transform the analysis of these data into a tractable and timely proposition, researchers at the NASA Glenn Research Center created and established the Rapid Analysis of Dynamic Data (RADD) system. The system provides complete, near real-time analysis of time-varying inlet airflow distortion datasets with report quality output. This fully digital approach employs Institute of Electrical and Electronics Engineers (IEEE) binary data file format standardization to establish data-acquisition-system-independent processing on low cost personal computers. Features include invalid instrumentation code-out, logging, and multiple replacement schemes as needed for each channel of instrumentation. The AIP pressure distribution can be interpolated to simulate measurements by alternate AIP probe arrays, if desired. In addition, the RADD system provides for the application of filters that can be used to focus the analysis on the frequency range of interest.

Arend, David J.

2004-01-01

316

In-vehicle human factors for integrated multi-function systems: Making ITS user-friendly  

SciTech Connect

As more and more Intelligent Transportation System in-vehicle equipment enters the general consumer market, the authors are about to find out how different design engineers are from ordinary drivers. Driver information systems are being developed and installed in vehicles at an ever-increasing rate. These systems provide information on diverse topics of concern and convenience to the driver, such as routing and navigation, emergency and collision warnings, and a variety of motorists services, or yellow pages functions. Most of these systems are being developed and installed in isolation from each other, with separate means of gathering the information and of displaying it to the driver. The current lack of coordination among on-board systems threatens to create a situation in which different messages on separate displays will be competing with each other for the drivers attention. Urgent messages may go unnoticed, and the number of messages may distract the driver from the most critical task of controlling the vehicle. Thus, without good human factors design and engineering for integrating multiple systems in the vehicle, consumers may find ITS systems confusing and frustrating to use. The current state of the art in human factors research and design for in-vehicle systems has a number of fundamental gaps. Some of these gaps were identified during the Intelligent Vehicle Initiative Human Factors Technology Workshop, sponsored by the US Department of Transportation, in Troy, Michigan, December 10--11, 1997. One task for workshop participants was to identify needed research areas or topics relating to in-vehicle human factors. The top ten unmet research needs from this workshop are presented. Many of these gaps in human factors research knowledge indicate the need for standardization in the functioning of interfaces for safety-related devices such as collision avoidance systems (CAS) and adaptive cruise controls (ACC). Such standards and guidelines will serve to make the safety-critical aspects of these systems consistent across different manufacturers, thereby reducing the likelihood of driver surprise. A second area to emerge from the Workshop concerns research into techniques for integrating multiple devices in vehicles. This type of research is needed to support the development and validation of standards and guidelines, and is discussed in the second section. The majority of the top ten research types identified in the Workshop fall under the need for a Science of Driving, which is discussed in the last section of this paper.

Spelt, P.F.; Scott, S.

1998-04-01

317

USER Friendly Cloning Coupled with Chitin-Based Natural Transformation Enables Rapid Mutagenesis of Vibrio vulnificus  

Microsoft Academic Search

Vibrio vulnificus is a bacterial contaminant of shellfish and causes highly lethal sepsis and destructive wound infections. A definitive identification of virulence factors using the molecular version of Koch's postulates has been hindered because of difficulties in performing molecular genetic analysis of this opportunistic pathogen. For example, conjugation is required to introduce plasmid DNA, and allelic exchange suicide vectors that

Paul A. Gulig; Matthew S. Tucker; Patrick C. Thiaville; Jennifer L. Joseph; Roslyn N. Brown

2009-01-01

318

User Friendly Bus Interior Design: Reducing Falls through Improved Visual Environment. 1. Executive Summary.  

National Technical Information Service (NTIS)

This report proposes cost-effective design guidelines to increase ride comfort, safety, and transit bus utility levels by specifying the visual cue requirements that will allow elderly riders to maintain a maximum sense of balance and spatial orientation....

B. J. Gilmore

1994-01-01

319

User-friendly, miniature biosensor flow cell for fragile high fundamental frequency quartz crystal resonators.  

PubMed

For the application of high fundamental frequency (HFF) quartz crystal resonators as ultra sensitive acoustic biosensors, a tailor-made quartz crystal microbalance (QCM) flow cell has been fabricated and tested. The cell permits an equally fast and easy installation and replacement of small and fragile HFF sensors. Usability and simple fabrication are two central features of the HFF-QCM flow cell. Mechanical, thermal, electrical and chemical requirements are considered. The design of the cell combines these, partially contradictory, requirements within a simple device. Central design concepts are discussed and a brief description of the fabrication, with a special focus on the preparation of crucial parts, is provided. For test measurements, the cell was equipped with a standard 50 MHz HFF resonator which had been surface-functionalised with a self-assembled monolayer of 1-octadecanethiol. The reliable performance is demonstrated with two types of experiments: the real time monitoring of phospholipid monolayer formation and its removal with detergent, as well as step-wise growth of a protein multilayer system by an alternating immobilisation of streptavidin and biotinylated immunoglobulin G. PMID:19231152

Sagmeister, Brigitte P; Graz, Ingrid M; Schwödiauer, Reinhard; Gruber, Hermann; Bauer, Siegfried

2009-04-15

320

Multichannel Protocols for User-Friendly and Scalable Initialization of Sensor Networks  

Microsoft Academic Search

We consider the classical problem of establishing initial security associations in wireless sensor networks. More specifically, we focus on pre-deployment phase in which sensor nodes\\u000a have not yet been loaded with shared secrets or other forms of authentic information.\\u000a \\u000a In this paper, we propose two novel multichannel protocols for initialization of large scale wireless sensor networks. The first protocol uses

Toni Perkovic; Ivo Stancic; Luka Malisa; Mario ?agalj

2009-01-01

321

Copyright Renewal for Libraries: Seven Steps toward a User-Friendly Law  

ERIC Educational Resources Information Center

Copyright law is a source of a great deal of bewilderment and frustration to academic librarians. Beyond the basics of copyright protection and fair use, most librarians struggle to grasp the complexity of the law and the roadblocks it presents to access and use. This article attempts to elucidate some of those complexities by suggesting seven…

Smith, Kevin L.

2010-01-01

322

Reflectivity and Transmissivity through Layered, Lossy Media: A User- Friendly Approach.  

National Technical Information Service (NTIS)

The theory behind the use of layers of radar absorbing materials or other dielectric materials is identical to the theory of optical reflection and transmission through layered media. This report is intended to be of use to students studying the applicati...

K. J. Pascoe

2001-01-01

323

Final report: Efficient and user friendly C++ library for differential algebra  

SciTech Connect

In Phase I we proposed the following tasks: Task 1: Identify the units of the Differential Algebra (DA) library, i.e. determine the abstract data types of the DA and the relations between them. Develop the interfaces (.h files) for the DA vectors. Task 2: Implement the DA vector class with garbage collection and expression templates for optimizing all overloaded operators by minimizing creation of temporaries and fusing loops. Task 3: Implement the prototype GUI for instantiating systems from files and invoking the DA methods. Task 4: Develop a suite of tests for the DA vector class and the needed utilities classes. Task 5: Write the final report on this work. This will include documentation on the use of the code. We have completed these tasks. In this section we discuss the results of our work.

Svetlana G. Shasharina

1998-09-29

324

Bioprocess Control in Microscale: Scalable Fermentations in Disposable and User-Friendly Microfluidic Systems  

Microsoft Academic Search

BACKGROUND: The efficiency of biotechnological production processes depends on selecting the best performing microbial strain and the optimal cultivation conditions. Thus, many experiments have to be conducted, which conflicts with the demand to speed up drug development processes. Consequently, there is a great need for high-throughput devices that allow rapid and reliable bioprocess development. This need is addressed, for example,

Matthias Funke; Andreas Buchenauer; Wilfried Mokwa; Stefanie Kluge; Lea Hein; Carsten Müller; Frank Kensy; Jochen Büchs

2010-01-01

325

Bootstrapping Key Pre-Distribution: Secure, Scalable and User-Friendly Initialization of Sensor Nodes  

Microsoft Academic Search

To establish secure (point-to-point and\\/or broadcast) communication channels\\u000aamong the nodes of a wireless sensor network is a fundamental task. To this\\u000aend, a plethora of (socalled) key pre-distribution schemes have been proposed\\u000ain the past. All these schemes, however, rely on shared secret(s), which are\\u000aassumed to be somehow pre-loaded onto the sensor nodes. In this paper, we\\u000apropose

Nitesh Saxena

2008-01-01

326

DEVELOPMENT OF USER-FRIENDLY SIMULATION SYSTEM OF EARTHQUAKE INDUCED URBAN SPREADING FIRE  

NASA Astrophysics Data System (ADS)

In the simulation of earthquake induced urban spreading fire, the produce of the analytical model of the target area is required as well as the analysis of spreading fire and the presentati on of the results. In order to promote the use of the simulation, it is important that the simulation system is non-intrusive and the analysis results can be demonstrated by the realistic presentation. In this study, the simulation system is developed based on the Petri-net algorithm, in which the easy operation can be realized in the modeling of the target area of the simulation through the presentation of analytical results by realistic 3-D animation.

Tsujihara, Osamu; Gawa, Hidemi; Hayashi, Hirofumi

327

TelEMA: a low-cost and user-friendly telephone assessment platform.  

PubMed

Ecological momentary assessment (EMA), or the repeated assessment of individuals' behaviors and experiences over time, is a methodologically advantageous approach to the study of psychological constructs. Recently, advances in computer technology have allowed for EMA research to be conducted in a more convenient, automated, and secure manner by administering surveys on participants' telephones and storing the results directly to a central server. The present article introduces TelEMA, an easy-to-use, low-cost telephone assessment platform for clinical and research applications. A single server running TelEMA can be shared among many experimenters, studies, and participants simultaneously. TelEMA routes telephone calls and text messages through a third-party service, so experimenters may conduct studies with no up-front cost or technical expertise. TelEMA provides a secure Web interface for experimenters or clinicians to design studies, enroll participants, monitor compliance, and collate response data from anywhere. Participants complete surveys using their own telephones. Surveys may contain keypress or voice recording questions, and the timing and content of each survey may be randomized and customized. A pilot study was conducted in which individuals used the TelEMA system to complete four randomly timed surveys per day for one week; the surveys assessed state affect and social anxiety. Results indicated that participants found TelEMA easy to use and secure, and compliance rates were on par with other EMA methods using mobile devices. Overall, TelEMA is a practical and robust system that enables fast and inexpensive deployment of EMAs. PMID:23239075

Fernandez, Katya C; Johnson, Matthew R; Rodebaugh, Thomas L

2013-12-01

328

Developing a Comprehensive Strategic Plan for Campus Computing: A User-Friendly Approach.  

ERIC Educational Resources Information Center

The Information Services Plan (ISP) developed at Howard Community College (HCC), in Columbia, Maryland, is designed to ensure that the necessary data, equipment, and communications technologies will be available to enable the college to meet its strategic goals. The plan provides for analyses of the current information services operating…

Burrill, Dwight A.; Copenhaver, Carol

329

Creating a user friendly GIS tool to define functional process zones  

EPA Science Inventory

The goal of this research is to develop methods and indicators that are useful for evaluating the condition of aquatic communities, for assessing the restoration of aquatic communities in response to mitigation and best management practices, and for determining the exposure of aq...

330

Social Circles: A 3D User Interface for Facebook  

NASA Astrophysics Data System (ADS)

Online social network services are increasingly popular web applications which display large amounts of rich multimedia content: contacts, status updates, photos and event information. Arguing that this quantity of information overwhelms conventional user interfaces, this paper presents Social Circles, a rich interactive visualization designed to support real world users of social network services in everyday tasks such as keeping up with friends and organizing their network. It achieves this by using 3D UIs, fluid animations and a spatial metaphor to enable direct manipulation of a social network.

Rodrigues, Diego; Oakley, Ian

331

User's operating procedures. Volume 1: Scout project information programs  

NASA Technical Reports Server (NTRS)

A review of the user's operating procedures for the Scout Project Automatic Data System, called SPADS is given. SPADS is the result of the past seven years of software development on a Prime minicomputer located at the Scout Project Office. SPADS was developed as a single entry, multiple cross reference data management and information retrieval system for the automation of Project office tasks, including engineering, financial, managerial, and clerical support. The instructions to operate the Scout Project Information programs in data retrieval and file maintenance via the user friendly menu drivers is presented.

Harris, C. G.; Harris, D. K.

1985-01-01

332

User's operating procedures. Volume 3: Projects directorate information programs  

NASA Technical Reports Server (NTRS)

A review of the user's operating procedures for the scout project automatic data system, called SPADS is presented. SPADS is the results of the past seven years of software development on a prime mini-computer. SPADS was developed as a single entry, multiple cross-reference data management and information retrieval system for the automation of Project office tasks, including engineering, financial, managerial, and clerical support. This volume, three of three, provides the instructions to operate the projects directorate information programs in data retrieval and file maintenance via the user friendly menu drivers.

Haris, C. G.; Harris, D. K.

1985-01-01

333

Taking Flight. An Introduction to Building Refuge Friends Organizations.  

National Technical Information Service (NTIS)

When the National Wildlife Refuge Association lanunched the Friends Initiative, it was clear that a basic guide book was needed to help citizens form new refuge Friends groups. Taking Flight is written for use by both citizens and refuge staff who are wor...

1997-01-01

334

Academic Achievement and Its Impact on Friend Dynamics  

ERIC Educational Resources Information Center

Academic achievement in adolescence is a key determinant of future educational and occupational success. Friends play an important role in the educational process. They provide support and resources and can both encourage and discourage academic achievement. As a result, the friends adolescents make may help to maintain and exacerbate inequality…

Flashman, Jennifer

2012-01-01

335

Older Women: The Meaning of Involvement With Family and Friends.  

ERIC Educational Resources Information Center

Because relationships with family and friends may cause stress for women, the effects of interactions with family, friends, and community on women's adaption to the experiences of aging are important. Interviews were conducted with 75 women between the ages of 44 and 77 who were educated, relieved of child-rearing responsibilities, and relatively…

Greenberg, Reva M.

336

Psychotherapy and Friendship: An Analysis of the Communications of Friends  

ERIC Educational Resources Information Center

Discusses results of two studies conducted to investigate communications between friends, since it is often stated that psychotherapy is a type of friendship. Findings showed that empathic responses were infrequent between friends trying to be helpful, though such responses constituted a majority of statements of model Rogerian therapists.…

Reisman, John M.; Yamokoski, Tom

1974-01-01

337

The Minnesota Family, Friend and Neighbor Grant Program  

ERIC Educational Resources Information Center

In 1997, Minnesota became the first state in the nation to pass legislation establishing an education and support program for family, friend, and neighbor (FFN) care providers. This article describes the Minnesota Family, Friend and Neighbor Grant Program and findings from an evaluation of the programs and a curriculum scan of materials used in…

Susman-Stillman, Amy; Stout, Karen; Cleveland, Jennifer; Hawley, Vicki

2011-01-01

338

A Little Help from My Friends: Creating Socially Supportive Schools  

ERIC Educational Resources Information Center

Students get by with a little help from their friends; students try with a little help from their friends. When their social needs are met, students tend to be better adjusted and perform more effectively in school. A strong social network serves to protect students and mitigates the effects of a variety of risk factors. Due to the rich empirical…

Sulkowski, Michael L.; Demaray, Michelle K.; Lazarus, Philip J.

2012-01-01

339

Creating a Responsive Website: PPLD Friends--A Case Study  

ERIC Educational Resources Information Center

The Friends of the Pikes Peak Library District (PPLD) had a legacy website that was remotely hosted and maintained by a volunteer. They wanted a more significant presence on PPLD.org and an easier interface with which to update information. The developers decided to create a new Friends site in Drupal, using RWD, CSS3, and HTML5. The plan was to…

Franklyn, Virginia

2013-01-01

340

Working the Social: Twitter and FriendFeed  

ERIC Educational Resources Information Center

Information overload is so five years ago, but the problem it describes is all too real. Fortunately, there's hope yet for the savvy librarian: Twitter and FriendFeed turn information dissemination on its head, using friends and subscribers as a filter for the best, most credible, and most engaging information out there. Like other social media…

Carscaddon, Laura; Harris, Colleen S.

2009-01-01

341

Children's and Their Friends' Moral Reasoning: Relations with Aggressive Behavior  

ERIC Educational Resources Information Center

Friends' moral characteristics such as their moral reasoning represent an important social contextual factor for children's behavioral socialization. Guided by this assumption, we compared the effects of children's and friends' moral reasoning on their aggressive behavior in a low-risk sample of elementary school children. Peer nominations and…

Gasser, Luciano; Malti, Tina

2012-01-01

342

Spammer and hacker, two old friends  

Microsoft Academic Search

Spammers are always looking for new ways to bypass filters and spread spam content. Currently, spammers have not only improved their spam methods but have also moved towards exploiting software security vulnerabilities in order to spread their spam content. Spammers use weaknesses inside Web applications to inject their spam content into legitimate Web sites, redirect users to their own campaign,

Pedram Hayati; Vidyasagar Potdar

2009-01-01

343

The crustal dynamics intelligent user interface anthology  

NASA Technical Reports Server (NTRS)

The National Space Science Data Center (NSSDC) has initiated an Intelligent Data Management (IDM) research effort which has, as one of its components, the development of an Intelligent User Interface (IUI). The intent of the IUI is to develop a friendly and intelligent user interface service based on expert systems and natural language processing technologies. The purpose of such a service is to support the large number of potential scientific and engineering users that have need of space and land-related research and technical data, but have little or no experience in query languages or understanding of the information content or architecture of the databases of interest. This document presents the design concepts, development approach and evaluation of the performance of a prototype IUI system for the Crustal Dynamics Project Database, which was developed using a microcomputer-based expert system tool (M. 1), the natural language query processor THEMIS, and the graphics software system GSS. The IUI design is based on a multiple view representation of a database from both the user and database perspective, with intelligent processes to translate between the views.

Short, Nicholas M., Jr.; Campbell, William J.; Roelofs, Larry H.; Wattawa, Scott L.

1987-01-01

344

User interface user's guide for HYPGEN  

NASA Technical Reports Server (NTRS)

The user interface (UI) of HYPGEN is developed using Panel Library to shorten the learning curve for new users and provide easier ways to run HYPGEN for casual users as well as for advanced users. Menus, buttons, sliders, and type-in fields are used extensively in UI to allow users to point and click with a mouse to choose various available options or to change values of parameters. On-line help is provided to give users information on using UI without consulting the manual. Default values are set for most parameters and boundary conditions are determined by UI to further reduce the effort needed to run HYPGEN; however, users are free to make any changes and save it in a file for later use. A hook to PLOT3D is built in to allow graphics manipulation. The viewpoint and min/max box for PLOT3D windows are computed by UI and saved in a PLOT3D journal file. For large grids which take a long time to generate on workstations, the grid generator (HYPGEN) can be run on faster computers such as Crays, while UI stays at the workstation.

Chiu, Ing-Tsau

1992-01-01

345

Viscosity and thermal conductivity of some refrigerants at moderate and high densities on the basis of Rainwater–Friend theory and the corresponding states principle  

Microsoft Academic Search

The initial density dependence of viscosity and thermal conductivity was formulated on the basis of Rainwater–Friend (RF) theory. In this work, we have first focused on the calculation of viscosity and thermal conductivity of moderately dense argon by using RF theory and an accurate ab initio potential function. This theory which was originally presented for spherical potentials have been adapted

Tayebeh Hosseinnejad; Hassan Behnejad

2008-01-01

346

Do Friends and Nonfriends Behave Differently? A Social Relations Analysis of Children's Behavior.  

ERIC Educational Resources Information Center

Examined how children behave differently with friends and non-friends. Engaged 123 triads of target children, friends, and unacquainted peers in free-play and planning tasks. Found that children behaved more positively but also exhibited more negative behavior with friends than with non-friends. (KK)

Simpkins, Sandra D.; Parke, Ross D.

2002-01-01

347

Two Types of Well Followed Users in the Followership Networks of Twitter  

PubMed Central

In the Twitter blogosphere, the number of followers is probably the most basic and succinct quantity for measuring popularity of users. However, the number of followers can be manipulated in various ways; we can even buy follows. Therefore, alternative popularity measures for Twitter users on the basis of, for example, users' tweets and retweets, have been developed. In the present work, we take a purely network approach to this fundamental question. First, we find that two relatively distinct types of users possessing a large number of followers exist, in particular for Japanese, Russian, and Korean users among the seven language groups that we examined. A first type of user follows a small number of other users. A second type of user follows approximately the same number of other users as the number of follows that the user receives. Then, we compare local (i.e., egocentric) followership networks around the two types of users with many followers. We show that the second type, which is presumably uninfluential users despite its large number of followers, is characterized by high link reciprocity, a large number of friends (i.e., those whom a user follows) for the followers, followers' high link reciprocity, large clustering coefficient, large fraction of the second type of users among the followers, and a small PageRank. Our network-based results support that the number of followers used alone is a misleading measure of user's popularity. We propose that the number of friends, which is simple to measure, also helps us to assess the popularity of Twitter users.

Saito, Kodai; Masuda, Naoki

2014-01-01

348

The ROYACS User Library.  

NASA Astrophysics Data System (ADS)

The main purpose with the ROYACS User Library is to provide ANA users at the Stockholm Observatory with suitable subprograms for data reduction of solar images. Other useful routines have also been included in order to improve the programming environment.

Löfdahl, M.

349

User fusion to constrain SAR targeting for TSTs  

Microsoft Academic Search

Synthetic aperture radar (SAR) automatic target recognition (ATR) systems will not be effective and efficient without incorporating the user in acquiring and identifying a target. Typically, a SAR-ATR goal is to automatically identify a target for a user; however, in most cases, the data resolution and data availability is not accurate enough to identify the target over all operating conditions.

Erik P. Blasch; Susan Plano

2003-01-01

350

PHAROS - Personalizing Users' Experience in Audio-Visual Online Spaces  

Microsoft Academic Search

The large volume of user generated content, although sometimes amateurish, represents a valuable source of information for audiovisual service providers. For example, companies and organizations can efficiently get feedback from consumers observing their online interaction with social media providers. Offering accurately personalized services is possible now, since users provide more personal information about themselves openly, which was previously much more

Raluca Paiu; Ling Chen; Claudiu S. Firan; Wolfgang Nejdl

2008-01-01

351

Multimodal Affective User Interface Using Wireless Devices for Emotion Identification  

Microsoft Academic Search

Emotion is a fundamental, essential, and critical function of human brain. It's desirable to create intelligent computer systems to make emotion identification accurate and reliable. Firstly, we discuss the importance of emotion research. Then, we report on our efforts in developing multimodal affective user interface system used in emotion identification. There are different modalities of synchronous inputs from the user

J. Z. Zhou; X. H. Wang

2005-01-01

352

Collaborative personalization on medical search engines using user exploratory survey  

Microsoft Academic Search

The surge of medical search engines in the web space is irrepressible. Medical search engines contain concise, structured and accurate information. As a result, medical search engines do not return cornucopia of search results to users. Search results returned by medical search engines are limited but relevant to a users query. Albeit a newcomer to the web, medical search engines

Anushia Inthiran; Saadat M. Alhashmi; Pervaiz K. Ahmed

2010-01-01

353

Assisting the “virtual” user  

Microsoft Academic Search

The development of online assistance for remote users of computer-based systems depends upon the assumptions made about the barriers users face and about the available strategies for addressing them. Drawing from the domain of digital libraries and information discovery and retrieval, this commentary speculates about missed opportunities hidden by those assumptions. Critical questions about strategies to remove user barriers, to

John Ober

1999-01-01

354

Dynamics of User Experience  

Microsoft Academic Search

This paper addresses the consideration of changes in user experience over time. We define user experience as a multidimensional phenomenon, that consists both of the perception of different product qualities and related emotions. First we will introduce the reader to our conceptualization of user experience and report empirical findings with respect to dynamic interactions. Secondly, we describe an experiment that

Michael Minge

355

Accurate models for EUV lithography  

NASA Astrophysics Data System (ADS)

Accurate modeling of EUV Lithography is a mandatory step in driving the technology towards its foreseen insertion point for 22-16nm node patterning. The models are needed to correct EUV designs for imaging effects, and to understand and improve the CD fingerprint of the exposure tools. With a full-field EUV ADT from ASML now available in the IMEC cleanroom, wafer data can be collected to calibrate accurate models and check if the existing modeling infrastructure can be extended to EUV lithography. As a first topic, we have measured the CD on wafer of a typical OPC dataset at different flare levels and modeled the evolution of wafer CD through flare, reticle CD, and pitch using Brion's Tachyon OPC engine. The modeling first requires the generation of a flare map using long-range kernels to model the EUV specific long-range flare. The accuracy of the flare map can be established independently from the CD measurements, by using the traditional disappearing pad test for flare determination (Kirk test). The flare map is then used as background intensity in the calibration of the traditional optical models with short-range kernels. For a structure set of 600 features and over a flare range of 4-6%, an rms fit value of 0.9nm was obtained. As a second aspect of the modeling, we have calibrated a full resist model to process window data. The full resist model is then used in a combination with experimental measurements of reticle CD, slit intensity uniformity, focal plane behavior, and EUV thick mask effects to model the evolution of wafer CD across the exposure field. The modeled evolution of CD across the exposure field was found to be a good match to the experimentally seen evolution of CD across the field, and confirms that the 4 factors mentioned above are main contributions to the CD uniformity across the field. As such the modeling work enables a better understanding of the errors contributing to CD variation across the field for EUV technology.

Hendrickx, Eric; Lorusso, Gian F.; Jiang, Jiong; Chen, Luoqi; Liu, Wei; van Setten, Eelco; Hansen, Steve

2009-10-01

356

How are lifetime polytobacco users different than current cigarette-only users? Results from a Canadian young adult population.  

PubMed

Current cigarette smoking combined with ever use of other tobacco products (lifetime polytobacco use) is important to examine as users may be at greater risk for illicit drug use, nicotine addiction, and adverse health outcomes. We determined estimates and patterns of lifetime polytobacco use and conducted multivariable analyses to determine demographic, family and friend, psychosocial, and lifestyle factors associated with use among a sample of Canadian young adults. Overall prevalence was 36.3% for current cigarette use; 10.1% for current cigarette use only and 26.2% for lifetime polytobacco use. Among polytobacco users, current cigarette use and ever cigar use was most frequent (67.2%). For males, the final model contained demographic, family and friends, and lifestyle factors. For females, the final model also included psychosocial factors. Illicit drug use was the strongest significant predictor for lifetime polytobacco use among males. We found gender specific differences when comparing lifetime polytobacco users to current cigarette-only users, in particular; male lifetime polytobacco users were more likely to use drugs and alcohol. Interventions focusing on individual substances should consider addressing combinations of use. PMID:19646820

Bombard, Jennifer M; Pederson, Linda L; Koval, John J; O'Hegarty, Michelle

2009-12-01

357

Accurate ab Initio Spin Densities  

PubMed Central

We present an approach for the calculation of spin density distributions for molecules that require very large active spaces for a qualitatively correct description of their electronic structure. Our approach is based on the density-matrix renormalization group (DMRG) algorithm to calculate the spin density matrix elements as a basic quantity for the spatially resolved spin density distribution. The spin density matrix elements are directly determined from the second-quantized elementary operators optimized by the DMRG algorithm. As an analytic convergence criterion for the spin density distribution, we employ our recently developed sampling-reconstruction scheme [J. Chem. Phys.2011, 134, 224101] to build an accurate complete-active-space configuration-interaction (CASCI) wave function from the optimized matrix product states. The spin density matrix elements can then also be determined as an expectation value employing the reconstructed wave function expansion. Furthermore, the explicit reconstruction of a CASCI-type wave function provides insight into chemically interesting features of the molecule under study such as the distribution of ? and ? electrons in terms of Slater determinants, CI coefficients, and natural orbitals. The methodology is applied to an iron nitrosyl complex which we have identified as a challenging system for standard approaches [J. Chem. Theory Comput.2011, 7, 2740].

2012-01-01

358

DOSFAC2 user`s guide  

SciTech Connect

This document describes the DOSFAC2 code, which is used for generating dose-to-source conversion factors for the MACCS2 code. DOSFAC2 is a revised and updated version of the DOSFAC code that was distributed with version 1.5.11 of the MACCS code. included are (1) an overview and background of DOSFAC2, (2) a summary of two new functional capabilities, and (3) a user`s guide. 20 refs., 5 tabs.

Young, M.L.; Chanin, D.

1997-12-01

359

DOSFAC2 user`s guide  

Microsoft Academic Search

This document describes the DOSFAC2 code, which is used for generating dose-to-source conversion factors for the MACCS2 code. DOSFAC2 is a revised and updated version of the DOSFAC code that was distributed with version 1.5.11 of the MACCS code. included are (1) an overview and background of DOSFAC2, (2) a summary of two new functional capabilities, and (3) a user`s

M. L. Young; D. Chanin

1997-01-01

360

Cold Friends of Hot Jupiters: AO Survey  

NASA Astrophysics Data System (ADS)

“Hot Jupiters” are a class of gas giant planets found in extrasolar systems at very small orbital distances (?0.05 AU). We know that these planets could not have formed at their present locations, but must instead have migrated in from beyond the ice line. One class of proposed migration mechanisms for these planets involve gravitational perturbations from a distant stellar companion. These same processes also provide a natural explanation for the existence of a subset of hot Jupiters that have been observed to have orbits that are highly misaligned with respect to their star's spin axis and/or have large orbital eccentricities. In the "Cold Friends" survey, we search for stellar companions around 51 stars known to host hot Jupiters in order to determine whether stellar companions play an important role in hot Jupiter migration. Our survey consists of a population of stars with planets that have eccentric and/or misaligned orbits as well as a control population of planets with well-aligned and circular orbits. This project searches for companion stars (the "Cold Friends") in three detection modes: radial velocity monitoring, high resolution IR spectroscopy (presented by D. Piskorz et al. at this meeting), and adaptive optics (AO) imaging at infrared wavelengths (presented here). The AO mode is sensitive to the most distant companions (separations of 50-200 AU and beyond) while the other modes are effective at finding companions at smaller separations. We present the results of our AO survey and discuss the binary fraction found in our sample. Out of our total sample of 51 stars, 19 candidate companions (many of which have not been observed before) were directly imaged around 17 stars. We also describe follow-up photometry and astrometry of all detected companions to determine whether or not they are gravitationally bound to the primary planet-hosting star. If such companions are common, it would suggest that perturbations from stellar companions may play a significant role in the evolution of hot Jupiter systems.

Ngo, Henry; Knutson, H. A.; Hinkley, S.; Crepp, J. R.; Batygin, K.; Howard, A. W.; Johnson, J. A.; Morton, T. D.; Muirhead, P. S.

2013-10-01

361

Lessons learned from a Canadian province-wide age-friendly initiative: the Age-Friendly Manitoba Initiative.  

PubMed

The Age-Friendly Manitoba Initiative was launched in 2008. A formative evaluation we conducted in 2011 with 44 participating rural and urban communities demonstrates considerable progress, with virtually all communities having formed an Age-Friendly Committee and conducting a community assessment to identify priorities for action. The majority of communities implemented one or more age-friendly projects. Major barriers to becoming age-friendly identified by participants included lack of funding; lack of capacity, particularly in small communities; and lack of leadership or direction. The study highlights the importance of strong leadership at all levels of government (municipal, provincial, federal); the need to support communities, particularly rural ones, as they try to become more age-friendly; and the importance of ongoing promotion of age-friendliness locally and more broadly (e.g., provincially). PMID:24224864

Menec, Verena H; Novek, Sheila; Veselyuk, Dawn; McArthur, Jennifer

2014-01-01

362

Becoming Friends on Online Social Networking Services  

Microsoft Academic Search

\\u000a The internet has become an effective tool in communication, and SNS (Social Networking Service), such as Facebook or Twitter,\\u000a that allows anyone to disclose a variety of specific personal information. The purpose of the present study is to identify\\u000a which profile factors provided SNS users (or viewers) with a positive first impression. Results from study 1, the three factors\\u000a -

Wonmi Ahn; Borum Kim; Kwang-Hee Han

363

Relocating from out-of-area treatments: service users' perspective.  

PubMed

Asylum closures over recent decades resulted in mental health services being increasingly sited in the community. However, under provision of highly supported accommodation led to service users being placed away from their local area in 'out-of-area treatments' (OATs). OATs have raised major concerns in relation to enabling service users' recovery, owing to limitations in promoting autonomy, social dislocation and costs. In 2004, an OATs project was set up in a London Borough to address these concerns. In the first 4 years, the project succeeded in relocating 22 service users to less restrictive environments locally. This study aims to explore the outcome of relocation from service users' perspective. A qualitative methodology was utilized. Semi-structured interviews were carried out with seven service users who relocated. All seven service users shared a strong aspiration for independent living but there was associated loneliness. Five welcomed increased contact with family and friends, but lacked social confidence, inhibiting social inclusion. Service users with long-term and consistent care managers were more able to address fears. Five out of seven service users concluded that relocation increased their autonomy thus enhanced their quality of life. PMID:22957942

Rambarran, D D

2013-10-01

364

The Schistosoma Granuloma: Friend or Foe?  

PubMed Central

Infection of man with Schistosoma species of trematode parasite causes marked chronic morbidity. Individuals that become infected with Schistosomes may develop a spectrum of pathology ranging from mild cercarial dermatitis to severe tissue inflammation, in particular within the liver and intestines, which can lead to life threatening hepatosplenomegaly. It is well established that the etiopathology during schistosomiasis is primarily due to an excessive or unregulated inflammatory response to the parasite, in particular to eggs that become trapped in various tissue. The eggs forms the foci of a classical type 2 granulomatous inflammation, characterized by an eosinophil-rich, CD4+ T helper (Th) 2 cell dominated infiltrate with additional infiltration of alternatively activated macrophages (M2). Indeed the sequela of the type 2 perioval granuloma is marked fibroblast infiltration and development of fibrosis. Paradoxically, while the granuloma is the cause of pathology it also can afford some protection, whereby the granuloma minimizes collateral tissue damage in the liver and intestines. Furthermore, the parasite is exquisitely reliant on the host to mount a granulomatous reaction to the eggs as this inflammatory response facilitates the successful excretion of the eggs from the host. In this focused review we will address the conundrum of the S. mansoni granuloma acting as both friend and foe in inflammation during infection.

Hams, Emily; Aviello, Gabriella; Fallon, Padraic G.

2013-01-01

365

Field Testing of Environmentally Friendly Drilling System  

SciTech Connect

The Environmentally Friendly Drilling (EFD) program addresses new low-impact technology that reduces the footprint of drilling activities, integrates light weight drilling rigs with reduced emission engine packages, addresses on-site waste management, optimizes the systems to fit the needs of a specific development sites and provides stewardship of the environment. In addition, the program includes industry, the public, environmental organizations, and elected officials in a collaboration that addresses concerns on development of unconventional natural gas resources in environmentally sensitive areas. The EFD program provides the fundamentals to result in greater access, reasonable regulatory controls, lower development cost and reduction of the environmental footprint associated with operations for unconventional natural gas. Industry Sponsors have supported the program with significant financial and technical support. This final report compendium is organized into segments corresponding directly with the DOE approved scope of work for the term 2005-2009 (10 Sections). Each specific project is defined by (a) its goals, (b) its deliverable, and (c) its future direction. A web site has been established that contains all of these detailed engineering reports produced with their efforts. The goals of the project are to (1) identify critical enabling technologies for a prototype low-impact drilling system, (2) test the prototype systems in field laboratories, and (3) demonstrate the advanced technology to show how these practices would benefit the environment.

David Burnett

2009-05-31

366

Maria Sklodowska-Curie - scientist, friend, manager  

NASA Astrophysics Data System (ADS)

Great names in science represent an inexhaustible source and richness of inspiration, satisfaction and consolation, a moving and victorious force. Throughout her exemplifying life, Maria Sklodowska remained modest but with a keen sense of humor, of an outstanding style, a mine of knowledge and experience, of innovative ideas and a rich inner life. Full of love, of passion to give and to share, of natural optimism, mixed with a light melancholy, so typical for sages. She vehemently defended the love of scientific research, of the spirit of adventure and entrepreneurship and fought for international culture, for the protection of personality and talent. Maria Sklodowska left her passion to science, her dedication to work including education and training of young people, her passionate adherence to her family, her belief in her friends, her pure and profound humanity and warmth! The paper should be a homage to her, an appreciation of her work over the years, but not less a correspondence, a conversation with her! On the other hand, the present solemn occasion resuscitates the personalities of Maria and Pierre Curie and their work, in particular of Maria Sklodowska in her own native land! In this manner, it truly contributes to her immortality!

Slavchev, A.

2009-01-01

367

Ants recognize foes and not friends  

PubMed Central

Discriminating among individuals and rejecting non-group members is essential for the evolution and stability of animal societies. Ants are good models for studying recognition mechanisms, because they are typically very efficient in discriminating ‘friends’ (nest-mates) from ‘foes’ (non-nest-mates). Recognition in ants involves multicomponent cues encoded in cuticular hydrocarbon profiles. Here, we tested whether workers of the carpenter ant Camponotus herculeanus use the presence and/or absence of cuticular hydrocarbons to discriminate between nest-mates and non-nest-mates. We supplemented the cuticular profile with synthetic hydrocarbons mixed to liquid food and then assessed behavioural responses using two different bioassays. Our results show that (i) the presence, but not the absence, of an additional hydrocarbon elicited aggression and that (ii) among the three classes of hydrocarbons tested (unbranched, mono-methylated and dimethylated alkanes; for mono-methylated alkanes, we present a new synthetic pathway), only the dimethylated alkane was effective in eliciting aggression. Our results suggest that carpenter ants use a fundamentally different mechanism for nest-mate recognition than previously thought. They do not specifically recognize nest-mates, but rather recognize and reject non-nest-mates bearing odour cues that are novel to their own colony cuticular hydrocarbon profile. This begs for a reappraisal of the mechanisms underlying recognition systems in social insects.

Guerrieri, Fernando J.; Nehring, Volker; J?rgensen, Charlotte G.; Nielsen, John; Galizia, C. Giovanni; d'Ettorre, Patrizia

2009-01-01

368

User's guide to resin infusion simulation program in the FORTRAN language  

NASA Technical Reports Server (NTRS)

RTMCL is a user friendly computer code which simulates the manufacture of fabric composites by the resin infusion process. The computer code is based on the process simulation model described in reference 1. Included in the user's guide is a detailed step by step description of how to run the program and enter and modify the input data set. Sample input and output files are included along with an explanation of the results. Finally, a complete listing of the program is provided.

Weideman, Mark H.; Hammond, Vince H.; Loos, Alfred C.

1992-01-01

369

Protein adducts for exposure monitoring: A computerized data base. Software and user's manual  

Microsoft Academic Search

The user's manual contains directions for the installation and use of the computerized Protein Adducts Database (CPAD). Most of the documentation is also available on-screen in the form of CPAD's Readme files and program prompts. CPAD, a user-friendly, menu-driven, stand-alone DBASE application, was created to provide an efficient means of updating and disseminating information on protein adducts relating to their

1992-01-01

370

ESPVI 4.0 ELECTROSTATIS PRECIPITATOR V-1 AND PERFORMANCE MODEL: USER'S MANUAL  

EPA Science Inventory

The manual is the companion document for the microcomputer program ESPVI 4.0, Electrostatic Precipitation VI and Performance Model. The program was developed to provide a user- friendly interface to an advanced model of electrostatic precipitation (ESP) performance. The program i...

371

ESPVI 4.0 ELECTROSTATIC PRECIPITATOR V-I AND PERFORMANCE MODEL: USER'S MANUAL  

EPA Science Inventory

The manual is the companion document for the microcomputer program ESPVI 4.0, Electrostatic Precipitation VI and Performance Model. The program was developed to provide a user- friendly interface to an advanced model of electrostatic precipitation (ESP) performance. The program i...

372

AF-Geospace User's Manual Version 1.4 and Version 1.4P.  

National Technical Information Service (NTIS)

The Air Force Research Laboratory master program AF-GEOSpace (Versions 1.4 and 1.4P) provides a user-friendly graphical interface to a variety of scientific models constructed to facilitate the assessment of natural hazards in the near-Earth space environ...

E. Holeman G. Ginet M. Tautz R. V. Hilmer T. Hall

1999-01-01

373

METAL FINISHING FACILITY RISK SCREENING TOOL (MFFRST): TECHNICAL DOCUMENTATION AND USER'S GUIDE  

EPA Science Inventory

The model MFFRST, short for Metal Finishing Facility Risk Screening Tool, is a user-friendly pc-based computer tool which allows an individual to evaluate the potential exposures and health risks to workers and nearby residents from emissions from individual metal finishing facil...

374

Metal Finishing Facility Risk Screening Tool (MFFRST): Technical Documentation and User's Guide (on CD-ROM).  

National Technical Information Service (NTIS)

The Metal Finishing Facility Risk Screening Tool (MFFRST), is a user-friendly tool that enables anyone to perform a screening characterization of health risks to workers and neighbors of metal finishing processes, was developed by the U.S. Environmental P...

2001-01-01

375

IAQPC: INDOOR AIR QUALITY SIMULATOR FOR PERSONAL COMPUTERS: VOLUME 2. USER'S GUIDE  

EPA Science Inventory

The two-volume report describes the development of an indoor air quality simulator for personal computers (IAQPC), a program that addresses the problems of indoor air contamination. The program-- systematic, user-friendly, and computer-based--can be used by administrators and eng...

376

Fast 3D Brain Segmentation Using Dual-Front Active Contours with Optional User-Interaction  

Microsoft Academic Search

Important attributes of 3D brain cortex segmentation algorithms include robustness, accuracy, computational efficiency, and facilitation of user interaction, yet few algorithms incorporate all of these traits. Manual segmentation is highly accurate but tedious and laborious. Most automatic techniques, while less demanding on the user, are much less accurate. It would be useful to employ a fast automatic segmentation procedure to

Hua Li; Anthony J. Yezzi; Laurent D. Cohen

2005-01-01

377

Microbial 'old friends', immunoregulation and socioeconomic status.  

PubMed

The immune system evolved to require input from at least three sources that we collectively term the 'old friends': (i) the commensal microbiotas transmitted by mothers and other family members; (ii) organisms from the natural environment that modulate and diversify the commensal microbiotas; and (iii) the 'old' infections that could persist in small isolated hunter-gatherer groups as relatively harmless subclinical infections or carrier states. These categories of organism had to be tolerated and co-evolved roles in the development and regulation of the immune system. By contrast, the 'crowd infections' (such as childhood virus infections) evolved later, when urbanization led to large communities. They did not evolve immunoregulatory roles because they either killed the host or induced solid immunity, and could not persist in hunter-gatherer groups. Because the western lifestyle and medical practice deplete the 'old' infections (for example helminths), immunoregulatory disorders have increased, and the immune system has become more dependent upon microbiotas and the natural environment. However, urbanization maintains exposure to the crowd infections that lack immunoregulatory roles, while accelerating loss of exposure to the natural environment. This effect is most pronounced in individuals of low socioeconomic status (SES) who lack rural second homes and rural holidays. Interestingly, large epidemiological studies indicate that the health benefits of living close to green spaces are most pronounced for individuals of low SES. Here we discuss the immunoregulatory role of the natural environment, and how this may interact with, and modulate, the proinflammatory effects of psychosocial stressors in low SES individuals. PMID:24401109

Rook, G A W; Raison, C L; Lowry, C A

2014-07-01

378

Bonobos protect and console friends and kin.  

PubMed

Post-conflict third-party affiliation has been reported to have different functional meanings, one of them being consolation. Here, we tested the main hypotheses that have been put forth to explain the presence of this phenomenon at a functional level in the bonobo: Self-Protection Hypothesis, Victim-Protection Hypothesis, Relationship-Repair or Substitute for Reconciliation Hypothesis, and Consolation Hypothesis. By analyzing the data collected over 10 years, we investigated what factors affected the distribution of both spontaneous third party affiliation (initiated by the bystander) and solicited third party affiliation (initiated by the victim). We considered factors related to the individual features (sex, rank, age) of victim and bystander, their relationship quality (kinship, affiliation), and the effect that third party affiliation had on the victim (such as protection against further attacks and anxiety reduction). Both spontaneous and solicited third party affiliation reduced the probability of further aggression by group members on the victim (Victim-Protection Hypothesis supported). Yet, only spontaneous affiliation reduced victim anxiety (measured via self-scratching), thus suggesting that the spontaneous gesture--more than the protection itself--works in calming the distressed subject. The victim may perceive the motivational autonomy of the bystander, who does not require an invitation to provide post-conflict affiliative contact. Moreover, spontaneous--but not solicited--third party affiliation was affected by the bond between consoler and victim, being the relationship between consoler and aggressor irrelevant to the phenomenon distribution (Consolation Hypothesis supported). Spontaneous affiliation followed the empathic gradient described for humans, being mostly offered to kin, then friends, then acquaintances. Overall, our findings do not only indicate the consolatory function of spontaneous third-party affiliation but they also suggest that consolation in the bonobo may be an empathy-based phenomenon. PMID:24223924

Palagi, Elisabetta; Norscia, Ivan

2013-01-01

379

Generic User Modeling Systems  

Microsoft Academic Search

The paper reviews the development of generic user modeling systems over the past twenty years. It describes their purposes, their services within user-adaptive systems, and the different design requirements for research prototypes and commerciallydeployed servers. It dis- cusses the architectures that have been explored so far, namely shell systems that form part oftheapplication,centralserversystemsthatcommunicatewithseveralapplications,andpossible future user modeling agents that physically follow

Alfred Kobsa

2001-01-01

380

Perceptions of friendship among youth with distressed friends.  

PubMed

This cross-sectional study examined the relationship between a friend's level of internalizing distress and the focal child's perceptions of friendship amongst 5th, 8th, and 11th grade youth. Participants completed the Youth Self-Report to assess internalizing distress and measures assessing perceptions of friendship quality, social support, and self-disclosure within reciprocal, same-sex friendship dyads. Results indicated that youth with friends experiencing low levels of internalizing distress reported poorer friendship quality and decreased levels of social support and self-disclosure within the friendship compared to youth with friends experiencing average or high internalizing distress. In a second set of analyses controlling for the focal child's own internalizing symptoms, gender, and age, friend's level of internalizing distress remained a significant, unique predictor of target participants' self-disclosure about their own problems within the friendship. The findings suggest that a mild degree of internalizing distress may enhance, rather than harm, friendships amongst youth. PMID:23605775

Hill, Erin N; Swenson, Lance P

2014-02-01

381

Somebody in My Friend's Family Died. What Should I Do?  

MedlinePLUS

... to be great," thought Kate. Her best friend, Sarah, had been absent from school for the last ... home from school had been lonely. She missed Sarah at lunchtime, too. But today Sarah was coming ...

382

Friend-foe Discrimination, Caffeine, and Sentry Duty.  

National Technical Information Service (NTIS)

In war, the sentry must continually and rapidly detect targets, correctly discriminate friend from foe and shoot with accuracy. Past research shows that caffeine enhances the sentry's target detection speed when all targets are foes. This study evaluates ...

R. F. Johnson D. J. Merullo

1999-01-01

383

Making and Keeping Friends: A Self-Help Guide  

MedlinePLUS

... Making Friends . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Guidelines for Keeping Your Friendships Strong. . . . . . . . 4 Establishing and Honoring Boundaries . . . . . . . . . . . . . . . 7 Resolving Problems ... connection even without any dialogue with others. ? Volunteer. Strong connections often are formed when people work together ...

384

76 FR 12989 - Draft Fish and Wildlife Service Friends Policy  

Federal Register 2010, 2011, 2012, 2013

...DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R9-R-2011-N030...93261-1263-000-5C] RIN 1018-AX35 Draft Fish and Wildlife Service Friends Policy AGENCY: Fish and Wildlife Service, Interior. ACTION:...

2011-03-09

385

Grid FriendlyTM Device Model Development and Simulation.  

National Technical Information Service (NTIS)

In late 2007, the Bonneville Power Administration (BPA) contracted Pacific Northwest National Laboratory (PNNL) to complete a research project titled Grid-Responsive Demand-Side Control Using Grid Friendly Appliance Technologies (Hammerstrom 2009, DeStees...

D. J. Hammerstrom N. Lu S. Patrick

2009-01-01

386

Preliminary ISIS users manual  

NASA Technical Reports Server (NTRS)

The Interactive Software Invocation (ISIS), an interactive data management system, was developed to act as a buffer between the user and host computer system. The user is provided by ISIS with a powerful system for developing software or systems in the interactive environment. The user is protected from the idiosyncracies of the host computer system by providing such a complete range of capabilities that the user should have no need for direct access to the host computer. These capabilities are divided into four areas: desk top calculator, data editor, file manager, and tool invoker.

Grantham, C.

1979-01-01

387

Patient-friendly IVF: how should it be defined?  

Microsoft Academic Search

Patient-friendly'' IVF must be associated with a healthy newborn achieved in a safe, cost-effective, and timely manner. Patients are best served when physicians provide honest appraisal of treatment techniques and out- comes using the evidence available from scientific study. (Fertil Steril? 2007;88:547-9. ? 2007 by American So- ciety for Reproductive Medicine.) Traditionally, physicians have defined ''patient-friendly'' care as the best

Eric Flisser; Richard T. Scott; Alan B. Copperman

2007-01-01

388

High School and Beyond: Friends [machine-readable data file].  

ERIC Educational Resources Information Center

The "Friends" machine-readable data file (MRDF) is a part of the larger "High School and Beyond" (HS&B) class of 1980 survey which was administered in 1980 to a national sample of over 30,000 sophomores and 28,000 seniors from 1,015 high schools throughout the United States. The "Friends" film includes data from over 58,000 respondents, all of…

National Opinion Research Center, Chicago, IL.

389

LLCEDATA and LLCECALC for Windows version 1.0, Volume 1: User`s manual  

SciTech Connect

LLCEDATA and LLCECALC for Windows are user-friendly computer software programs that work together to determine the proper waste designation, handling, and disposition requirements for Long Length Contaminated Equipment (LLCE). LLCEDATA reads from a variety of data bases to produce an equipment data file (EDF) that represents a snapshot of both the LLCE and the tank it originates from. LLCECALC reads the EDF and a gamma assay (AV2) file that is produced by the Flexible Receiver Gamma Energy Analysis System. LLCECALC performs corrections to the AV2 file as it is being read and characterizes the LLCE. Both programs produce a variety of reports, including a characterization report and a status report. The status report documents each action taken by the user, LLCEDATA, and LLCECALC. Documentation for LLCEDATA and LLCECALC for Windows is available in three volumes. Volume 1 is a user`s manual, which is intended as a quick reference for both LLCEDATA and LLCECALC. Volume 2 is a technical manual, and Volume 3 is a software verification and validation document.

McFadden, J.G.

1998-09-04

390

PEDRO (Petroleum Electronic Data Reporting Option) user guide  

SciTech Connect

PEDRO is an electronic data communications product that simplifies filing and transmission of petroleum survey data. Your burden is significantly reduced as PEDRO eliminates paperwork, provides immediate onsite correction of data errors, and reduces the need for followup calls and survey resubmission. PEDRO provides an online error-checking process that highlights discrepancies. This permits you to enter and check data before transmitting to EIA. EIA then combines and reformats the data from different users for use by analytical and reporting programs. PEDRO is available at no cost to the user. Formal training is not required since installation, data processing, and transmission are done by interactive, user-friendly menu options. The PEDRO system is divided into three functions: (1) data processing, (2) transmitting data to EIA, and (3) EIA processing. 28 figs.

Not Available

1990-11-01

391

Top ten list of user-hostile interface design  

SciTech Connect

This report describes ten of the most frequent ergonomic problems found in human-computer interfaces (HCIs) associated with complex industrial machines. In contrast with being thought of as ``user friendly,`` many of these machines are seen as exhibiting ``user-hostile`` attributes by the author. The historical lack of consistent application of ergonomic principles in the HCIs has led to a breed of very sophisticated, complex manufacturing equipment that few people can operate without extensive orientation, training, or experience. This design oversight has produced the need for extensive training programs and help documentation, unnecessary machine downtime, and reduced productivity resulting from operator stress and confusion. Ergonomic considerations affect industrial machines in at least three important areas: (1) the physical package including CRT and keyboard, maintenance access areas, and dedicated hardware selection, layout, and labeling; (2) the software by which the user interacts with the computer that controls the equipment; and (3) the supporting documentation.

Miller, D.P.

1994-10-01

392

NASTRAN: Users' experiences  

NASA Technical Reports Server (NTRS)

The proceedings of a conference on NASA Structural Analysis (NASTRAN) to analyze the experiences of users of the program are presented. The subjects discussed include the following: (1) statics and buckling, (2) vibrations and dynamics, (3) substructing, (4) new capability, (5) user's experience, and (6) system experience. Specific applications of NASTRAN to spacecraft, aircraft, nuclear power plants, and materials tests are reported.

1973-01-01

393

Map Navigator: User Documentation.  

National Technical Information Service (NTIS)

This documentation was written to help provide the user with a better understanding of the Map Navigator software. The best way to learn the software, however, is through hands-on use. This documentation provides examples for the user to go through and tr...

B. Powell D. Mayfield

1993-01-01

394

Users of Cannabis Only.  

National Technical Information Service (NTIS)

Subjects who have used only cannabis were compared with those who have used cannabis along with other drugs, and with a control sample on whom no drug-using information was available. Results indicate that cannabis-only users are more effective than users...

C. J. Mullins B. M. Vitola J. W. Abellera

1974-01-01

395

Accelerator facilities users' guide.  

National Technical Information Service (NTIS)

In 1981 the ''Green Book'' of SIN was distributed, a User Handbook serving the needs of people already working at SIN as well as informing new users about our installations. An update of the Green Book is necessary because many beams have disappeared, bee...

H. C. Walter L. Adrion R. Frosch M. Salzmann

1994-01-01

396

KDYNA user's manual  

SciTech Connect

This report is a complete user's manual for KDYNA, the Earth Sciences version of DYNA2D. Because most features of DYNA2D have been retained in KDYNA much of this manual is identical to the DYNA2D user's manual.

Levatin, J.A.L.; Attia, A.V.; Hallquist, J.O.

1990-09-28

397

MIRADS-2 user's manual  

NASA Technical Reports Server (NTRS)

An on-line data storage and retrieval system which allows the user to extract and process information from stored data bases is described. The capabilities of the system are provided by a general purpose computer program containing several functional modules. The modules contained in MIRADS are briefly described along with user terminal operation procedures and MIRADS commands.

1975-01-01

398

Online Access: User Reaction.  

ERIC Educational Resources Information Center

Surveys reactions of students and faculty to the online circulation system at University of Guelph Library, Ontario. Findings concerning status of users, frequency of use, effectiveness of instructions on screen, convenience of terminal locations, type of information required by user, and general comments are noted. Four references are provided.…

Pawley, Carolyn

1982-01-01

399

User interface support  

NASA Technical Reports Server (NTRS)

Space construction will require heavy investment in the development of a wide variety of user interfaces for the computer-based tools that will be involved at every stage of construction operations. Using today's technology, user interface development is very expensive for two reasons: (1) specialized and scarce programming skills are required to implement the necessary graphical representations and complex control regimes for high-quality interfaces; (2) iteration on prototypes is required to meet user and task requirements, since these are difficult to anticipate with current (and foreseeable) design knowledge. We are attacking this problem by building a user interface development tool based on extensions to the spreadsheet model of computation. The tool provides high-level support for graphical user interfaces and permits dynamic modification of interfaces, without requiring conventional programming concepts and skills.

Lewis, Clayton; Wilde, Nick

1989-01-01

400

Do adolescent Ecstasy users have different attitudes towards drugs when compared to Marijuana users?  

PubMed Central

Background Perceived risk and attitudes about the consequences of drug use, perceptions of others expectations and self-efficacy influence the intent to try drugs and continue drug use once use has started. We examine associations between adolescents’ attitudes and beliefs towards ecstasy use; because most ecstasy users have a history of marijuana use, we estimate the association for three groups of adolescents: non-marijuana/ecstasy users, marijuana users (used marijuana at least once but never used ecstasy) and ecstasy users (used ecstasy at least once). Methods Data from 5,049 adolescents aged 12–18 years old who had complete weighted data information in Round 2 of the Restricted Use Files (RUF) of the National Survey of Parents and Youth (NSPY). Data were analyzed using jackknife weighted multinomial logistic regression models. Results Adolescent marijuana and ecstasy users were more likely to approve of marijuana and ecstasy use as compared to non-drug using youth. Adolescent marijuana and ecstasy users were more likely to have close friends who approved of ecstasy as compared to non-drug using youth. The magnitudes of these two associations were stronger for ecstasy use than for marijuana use in the final adjusted model. Our final adjusted model shows that approval of marijuana and ecstasy use was more strongly associated with marijuana and ecstasy use in adolescence than perceived risk in using both drugs. Conclusion Information about the risks and consequences of ecstasy use need to be presented to adolescents in order to attempt to reduce adolescents’ approval of ecstasy use as well as ecstasy experimentation.

Martins, Silvia S.; Storr, Carla L.; Alexandre, Pierre K.; Chilcoat, Howard D.

2008-01-01

401

Contextual profiles of young adult Ecstasy users: a multisite study  

PubMed Central

These analyses assess contextual profiles of 612 young adult Ecstasy users, 18–30 years of age, from St. Louis (USA), Miami (USA) and Sydney (Australia). Bivariate analyses revealed different contextual factors influencing Ecstasy use. Friends were the most common sources of Ecstasy at all sites and most used with friends. St. Louis and Miami use mostly occurred in residences, whereas in Sydney use was mostly at clubs, bars or restaurants. Ecstasy consumption at public places and in cars, trains or ferries was significantly higher in Miami (89% and 77%) than in St. Louis (67% and 65%) and Sydney (67% and 61%). At all sites, simultaneous use of LSD/mushroom and nitrous oxide with Ecstasy was common; concurrent amphetamines predominated in Sydney and heroin/opiates in St. Louis Contextual factors influencing Ecstasy use among young adults vary by geographic region. Their inclusion may help tailor effective prevention programs to reduce or ameliorate Ecstasy use.

Ramtekkar, Ujjwal P.; Striley, Catherine W; Cottler, Linda B

2010-01-01

402

Friends don't let friends suffer from depression: how threat, efficacy, knowledge, and empathy relate to college students'; intentions to intervene on behalf of a depressed friend.  

PubMed

Mental health-specifically, depression-is of growing concern to health professionals and the public. Health messages can be used to increase the number of people receiving treatment for depressive disorders. The effectiveness of these messages may be amplified by including an interpersonal influence component, such as encouraging individuals to intervene if they suspect a friend or family member is suffering from depression. The purposes of this study were to (a) explore college students'; behavioral intentions when presented with an opportunity to intervene on behalf of a depressed friend, (b) examine the potential of the Extended Parallel Process Model to help direct message design using efficacy and threat, and (c) investigate the respective influences of empathy and knowledge on behavioral intentions related to intervening on behalf of a depressed friend. Results indicated that self-efficacy and response efficacy, as well as perceived knowledge, could be used to help determine students'; readiness to talk with a friend who may be suffering from depression. Empathy (specifically empathic concern and perspective-taking) can also play a significant role in health promotion efforts that blend media and interpersonal health messages. PMID:24377435

Egbert, Nichole; Miraldi, Lori B; Murniadi, Krishnamurti

2014-04-01

403

Eco-Friendly Business Practices Can Create Opportunities For Innovation  

NSDL National Science Digital Library

Global warming, along with other ecological concerns have made environmental health a national and global issue in every industry. The social, governmental and economic pressures have created the need for companies to develop eco-friendly business practices while maintaining efficiency. For decades, scientists and environmental groups have been warning industry, consumers and governmental leaders about the drastic effects of pollution and the depletion of natural resources. However, only recently have companies begun to recognize the opportunities created when implementing strategies to address environmental concerns. Traditionally, business leaders regarded the environment and natural resources as unlimited factors of production that were readily available at little or no cost. Today, the concerns about pollution and the need for the efficient use of resources are forcing companies throughout the world to reevaluate their operations in order to become more ecologically conscious while remaining competitive. Fortunately, due to creative problem-solving and a greater understanding of eco-friendly business practices, companies are discovering that they can satisfy environmental concerns, while simultaneously cutting energy costs, boosting productivity and promoting innovation. The recognition of eco-friendly business practices as win-win opportunities are encouraging more companies to undertake these initiatives. Conversely, those organizations that arent eco-friendly and fail to address ecological concerns will forgo the opportunities for positive change and suffer financially in the long run. As future environmental managers and industry leaders, engineering and technology students need to understand the benefits of eco-friendly business practices. Consequently, it is important for their academic programs to provide students with an understanding of environmental health and related concerns. This paper will describe how companies can use eco-friendly business practices as opportunities to promote innovation. The paper will identify the benefits to business organizations and the environment when eco-friendly business practices are implemented.

Mcfarlane, Opal; Ocon, Ralph

2009-09-29

404

MFIX documentation: User`s manual  

SciTech Connect

MFIX (Multiphase Flow with Interphase exchanges) is a general-purpose hydro-dynamic model for describing chemical reactions and heat transfer in dense or dilute fluid-solids flows, which typically occur in energy conversion and chemical processing reactors. MFIX calculations give time-dependent information on pressure, temperature, composition, and velocity distributions in the reactors. The theoretical basis of the calculations is described in the MFIX Theory Guide. This report, which is the MFIX User`s Manual, gives an overview of the numerical technique, and describes how to install the MFIX code and post-processing codes, set up data files and run MFIX, graphically analyze MFIX results, and retrieve data from the output files. Two tutorial problems that highlight various features of MFIX are also discussed.

Syamlal, M.

1994-11-01

405

User`s guide to MIDAS  

SciTech Connect

Welcome to the MIDAS User`s Guide. This document describes the goals of the Munitions Items Disposition Action System (MIDAS) program and documents the MIDAS software. The main text first describes the equipment and software you need to run MIDAS and tells how to install and start it. It lists the contents of the database and explains how it is organized. Finally, it tells how to perform various functions, such as locating, entering, viewing, deleting, changing, transferring, and printing both textual and graphical data. Images of the actual computer screens accompany these explanations and guidelines. Appendix A contains a glossary of names for the various abbreviations, codes, and chemicals; Appendix B is a list of modem names; Appendix C provides a database dictionary and rules for entering data; and Appendix D describes procedures for troubleshooting problems associated with connecting to the MIDAS server and using MIDAS.

Tisue, S.A.; Williams, N.B.; Huber, C.C. [Argonne National Lab., IL (United States). Decision and Information Sciences Div.] [Argonne National Lab., IL (United States). Decision and Information Sciences Div.; Chun, K.C. [Argonne National Lab., IL (United States). Environmental Assessment Div.] [Argonne National Lab., IL (United States). Environmental Assessment Div.

1995-12-01

406

SEAPAK user's guide, version 2.0. Volume 2: Descriptions of programs  

NASA Technical Reports Server (NTRS)

The SEAPAK is a user-interactive satellite data analysis package that was developed for the processing and interpretation of Nimbus-7/Coastal Zone Color Scanner (CZCS) and the NOAA Advanced Very High Resolution Radiometer (AVHRR) data. Significant revisions were made since version 1.0, and the ancillary environmental data analysis module was greatly expanded. The package continues to be user friendly and user interactive. Also, because the scientific goals of the ocean color research being conducted have shifted to large space and time scales, batch processing capabilities for both satellite and ancillary environmental data analyses were enhanced, thus allowing for large quantities of data to be ingested and analyzed.

Mcclain, Charles R.; Darzi, Michael; Firestone, James K.; Fu, Gary; Yeh, Eueng-Nan; Endres, Daniel L.

1991-01-01

407

The "Digital Friend": A knowledge-based decision support system for space crews  

NASA Astrophysics Data System (ADS)

Space travel of far distances presents exceptional strain on the medical and psychological well-being of the astronauts who undertake such missions. An intelligent knowledge management system has been developed, to assist space crews on long-duration missions as an autonomous decision support system, called the "Digital Friend". This system will become available upon request for the purpose of coaching group processes and individual performance levels as well as aiding in tactical decision processes by taking crew condition parameters into account. In its initial stage, the "Digital Friend" utilizes interconnected layers of knowledge, which encompass relevant models of operational, situational, individual psycho-physiological as well as group processes. An example is the human life science model that contains historic, diagnostic, and prognostic knowledge about the habitual, actual, and anticipated patterns of physiological, cognitive, and group psychology parameters of the crew members. Depending on the available data derived from pre-mission screening, regular check-ups, or non-intrusive onboard monitoring, the "Digital Friend" can generate a situational analysis and diagnose potential problems. When coping with the effects of foreseeable and unforeseen stressors encountered during the mission, the system can provide feedback and support the crew with a recommended course of actions. The first prototype of the "Digital Friend" employs the Neurolab/Healthlab platform developed in a cooperation of DLR and IBMP. The prototype contains psycho-physiological sensors with multiple Heally Satellites that relay data to the intelligent Heally Masters and a telemetric Host station. The analysis of data from a long-term simulation study illustrates how the system can be used to estimate the operators' current level of skill reliability based on Salnitski's model [V. Salnitski, A. Bobrov, A. Dudukin, B. Johannes, Reanalysis of operators reliability in professional skills under simulated and real space flight conditions, Proceedings of the 55th IAC Congress, 4-8 October 2004, Vancouver, Canada ], which combines time-series information of work performance and of work effort. In further collaborative projects, the subsequent system development will pursue a series of studies in related terrestrial environments to validate and fabricate different sensor systems, as well as to tune the data-processing engine and to test suitable user interfaces.

Hoermann, Hans-Juergen; Johannes, Bernd; Petrovich Salnitski, Vyacheslav

408

User Models in Dialog Systems  

Microsoft Academic Search

This chapter surveys the field of user modeling in artificial intelligence dialog systems. First, reasons why user modeling has become so important in the last few years are pointed out, and definitions are proposed for the terms 'user model' and 'user modeling component'. Research within and outside of artificial intelligence which is related to user modeling in dialog systems is

Wolfgang Wahlster; Alfred Kobsa

1988-01-01

409

DOE-1: Users Guide.  

National Technical Information Service (NTIS)

DOE-1 is a public-domain computer program that allows users to explore the energy behavior of proposed and existing buildings and their associated heating, ventilation, and air-conditioning systems. Incorporating mathematical models and utilizing hourly w...

1978-01-01

410

Interactive Office User's Manual.  

National Technical Information Service (NTIS)

Given here is a user's manual for Interactive Office (IO), an executive office tool for organization and planning, written specifically for Macintosh. IO is a paperless management tool to automate a related group of individuals into one productive system.

E. E. Montgomery B. Lowers T. L. Nabors

1990-01-01

411

Interactive Office user's manual  

NASA Technical Reports Server (NTRS)

Given here is a user's manual for Interactive Office (IO), an executive office tool for organization and planning, written specifically for Macintosh. IO is a paperless management tool to automate a related group of individuals into one productive system.

Montgomery, Edward E.; Lowers, Benjamin; Nabors, Terri L.

1990-01-01

412

The Users of Indexes.  

National Technical Information Service (NTIS)

Problems of indexing and index use lie at the heart of information use. They determine maximum possible use of information use. They determine maximum possible use of information systems and sources, affect communication with users, influence the use of r...

C. Beal

1980-01-01

413

PRUNE - SIM Users Guide.  

National Technical Information Service (NTIS)

PRUNE-SIM is a spreadsheet template (program) that allows users to simulate a financial analysis of pruning coast Douglas-fir (Pseudotsuga menziesii (Mirb.) Franco var. menziesii). The program estimates the increase in product value resulting from pruning...

R. D. Fight J. M. Cahill T. A. Snellgrove T. D. Fahey

1987-01-01

414

Bullet Trap User's Guide.  

National Technical Information Service (NTIS)

This Bullet Trap User's Guide provides range management professionals with direction for choosing, installing, and maintaining bullet traps to solve metal migration, erosion, or safety problems on their outdoor small arms ranges. Bullet traps provide envi...

1996-01-01

415

Electronic Commerce user manual.  

National Technical Information Service (NTIS)

This User Manual supports the Electronic Commerce Standard System. The Electronic Commerce Standard System is being developed for the Department of Defense of the Technology Information Systems Program at the Lawrence Livermore National Laboratory, operat...

1992-01-01

416

FAST User Guide  

NASA Technical Reports Server (NTRS)

The Flow Analysis Software Toolkit, FAST, is a software environment for visualizing data. FAST is a collection of separate programs (modules) that run simultaneously and allow the user to examine the results of numerical and experimental simulations. The user can load data files, perform calculations on the data, visualize the results of these calculations, construct scenes of 3D graphical objects, and plot, animate and record the scenes. Computational Fluid Dynamics (CFD) visualization is the primary intended use of FAST, but FAST can also assist in the analysis of other types of data. FAST combines the capabilities of such programs as PLOT3D, RIP, SURF, and GAS into one environment with modules that share data. Sharing data between modules eliminates the drudgery of transferring data between programs. All the modules in the FAST environment have a consistent, highly interactive graphical user interface. Most commands are entered by pointing and'clicking. The modular construction of FAST makes it flexible and extensible. The environment can be custom configured and new modules can be developed and added as needed. The following modules have been developed for FAST: VIEWER, FILE IO, CALCULATOR, SURFER, TOPOLOGY, PLOTTER, TITLER, TRACER, ARCGRAPH, GQ, SURFERU, SHOTET, and ISOLEVU. A utility is also included to make the inclusion of user defined modules in the FAST environment easy. The VIEWER module is the central control for the FAST environment. From VIEWER, the user can-change object attributes, interactively position objects in three-dimensional space, define and save scenes, create animations, spawn new FAST modules, add additional view windows, and save and execute command scripts. The FAST User Guide uses text and FAST MAPS (graphical representations of the entire user interface) to guide the user through the use of FAST. Chapters include: Maps, Overview, Tips, Getting Started Tutorial, a separate chapter for each module, file formats, and system administration.

Walatka, Pamela P.; Clucas, Jean; McCabe, R. Kevin; Plessel, Todd; Potter, R.; Cooper, D. M. (Technical Monitor)

1994-01-01

417

Program Trains NASTRAN Users  

NASA Technical Reports Server (NTRS)

Rockwell Environment and NASTRAN Trainer (RENT) computer program developed to assist new and current users of NASTRAN finite-element computer code. Provides organized, systematic collection of IBM(R) features consisting of panels, clists, skeletons, and messages, along with FORTRAN and Pascal programs and example NASTRAN data files. Enables each user to learn at his or her own pace. Written in VS/FORTRAN, VS/ Pascal, and IBM(R) job-control language for an IBM(R) computer system.

Grooms, H. R.; Hinz, P. J.; Collier, M. A.; Cox, Kim D.; Merriman, Warren J.; Commerford, Gerry

1994-01-01

418

Getting to Family-Friendly in Your Department  

NASA Astrophysics Data System (ADS)

These days, most academic and research institutions recognize the importance of a family-friendly workplace, and have implemented at least some policies to support a sustainable work-life balance: family and medical leave, parental leave, stopping or extending tenure clocks, modified duty policies, breast feeding policies and lactation rooms, partner hiring programs, childcare programs, eldercare programs, emergency and sick child care programs, dependent care travel funds, etc. But while institutions may offer a menu of policies and free or low-cost services to support families, what's happening in your department? Achieving a supportive workplace culture requires that we dispel some of the myths associated with family-friendly policies, and establish that family-friendly policies not only benefit all employees, but also help the institution be more successful.

Pilachowski, Catherine A.

2012-01-01

419

Metadata: A user`s view  

SciTech Connect

An analysis is presented of the uses of metadata from four aspects of database operations: (1) search, query, retrieval, (2) ingest, quality control, processing, (3) application to application transfer; (4) storage, archive. Typical degrees of database functionality ranging from simple file retrieval to interdisciplinary global query with metadatabase-user dialog and involving many distributed autonomous databases, are ranked in approximate order of increasing sophistication of the required knowledge representation. An architecture is outlined for implementing such functionality in many different disciplinary domains utilizing a variety of off the shelf database management subsystems and processor software, each specialized to a different abstract data model.

Bretherton, F.P. [Univ. of Wisconsin, Madison, WI (United States); Singley, P.T. [Oak Ridge National Lab., TN (United States)

1994-12-31

420

The missing graphical user interface for genomics.  

PubMed

The Galaxy package empowers regular users to perform rich DNA sequence analysis through a much-needed and user-friendly graphical web interface. See research article http://genomebiology.com/2010/11/8/R86 RESEARCH HIGHLIGHT: With the advent of affordable and high-throughput DNA sequencing, sequencing is becoming an essential component in nearly every genetics lab. These data are being generated to probe sequence variations, to understand transcribed, regulated or methylated DNA elements, and to explore a host of other biological features across the tree of life and across a range of environments and conditions. Given this deluge of data, novices and experts alike are facing the daunting challenge of trying to analyze the raw sequence data computationally. With so many tools available and so many assays to analyze, how can one be expected to stay current with the state of the art? How can one be expected to learn to use each tool and construct robust end-to-end analysis pipelines, all while ensuring that input formats, command-line options, sequence databases and program libraries are set correctly? Finally, once the analysis is complete, how does one ensure the results are reproducible and transparent for others to scrutinize and study?In an article published in Genome Biology, Jeremy Goecks, Anton Nekrutenko, James Taylor and the rest of the Galaxy Team (Goecks et al. 1) make a great advance towards resolving these critical questions with the latest update to their Galaxy Project. The ambitious goal of Galaxy is to empower regular users to carry out their own computational analysis without having to be an expert in computational biology or computer science. Galaxy adds a desperately needed graphical user interface to genomics research, making data analysis universally accessible in a web browser, and freeing users from the minutiae of archaic command-line parameters, data formats and scripting languages. Data inputs and computational steps are selected from dynamic graphical menus, and the results are displayed in intuitive plots and summaries that encourage interactive workflows and the exploration of hypotheses. The underlying data analysis tools can be almost any piece of software, written in any language, but all their complexity is neatly hidden inside of Galaxy, allowing users to focus on scientific rather than technical questions. PMID:20804568

Schatz, Michael C

2010-01-01

421

CMGTooL user's manual  

USGS Publications Warehouse

During the past several years, the sediment transport group in the Coastal and Marine Geology Program (CMGP) of the U. S. Geological Survey has made major revisions to its methodology of processing, analyzing, and maintaining the variety of oceanographic time-series data. First, CMGP completed the transition of the its oceanographic time-series database to a self-documenting NetCDF (Rew et al., 1997) data format. Second, CMGP’s oceanographic data variety and complexity have been greatly expanded from traditional 2-dimensional, single-point time-series measurements (e.g., Electro-magnetic current meters, transmissometers) to more advanced 3-dimensional and profiling time-series measurements due to many new acquisitions of modern instruments such as Acoustic Doppler Current Profiler (RDI, 1996), Acoustic Doppler Velocitimeter, Pulse-Coherence Acoustic Doppler Profiler (SonTek, 2001), Acoustic Bacscatter Sensor (Aquatec, 1001001001001001001). In order to accommodate the NetCDF format of data from the new instruments, a software package of processing, analyzing, and visualizing time-series oceanographic data was developed. It is named CMGTooL. The CMGTooL package contains two basic components: a user-friendly GUI for NetCDF file analysis, processing and manipulation; and a data analyzing program library. Most of the routines in the library are stand-alone programs suitable for batch processing. CMGTooL is written in MATLAB computing language (The Mathworks, 1997), therefore users must have MATLAB installed on their computer in order to use this software package. In addition, MATLAB’s Signal Processing Toolbox is also required by some CMGTooL’s routines. Like most MATLAB programs, all CMGTooL codes are compatible with different computing platforms including PC, MAC, and UNIX machines (Note: CMGTooL has been tested on different platforms that run MATLAB 5.2 (Release 10) or lower versions. Some of the commands related to MAC may not be compatible with later releases of MATLAB). The GUI and some of the library routines call low-level NetCDF file I/O, variable and attribute functions. These NetCDF exclusive functions are supported by a MATLAB toolbox named NetCDF, created by Dr. Charles Denham . This toolbox has to be installed in order to use the CMGTooL GUI. The CMGTooL GUI calls several routines that were initially developed by others. The authors would like to acknowledge the following scientists for their ideas and codes: Dr. Rich Signell (USGS), Dr. Chris Sherwood (USGS), and Dr. Bob Beardsley (WHOI). Many special terms that carry special meanings in either MATLAB or the NetCDF Toolbox are used in this manual. Users are encouraged to read the documents of MATLAB and NetCDF for references.

Xu, Jingping; Lightsom, Fran; Noble, Marlene A.; Denham, Charles

2002-01-01

422

Aerial image retargeting (AIR): achieving litho-friendly designs  

NASA Astrophysics Data System (ADS)

In this work, we present a new technique to detect non-Litho-Friendly design areas based on their Aerial Image signature. The aerial image is calculated for the litho target (pre-OPC). This is followed by the fixing (retargeting) the design to achieve a litho friendly OPC target. This technique is applied and tested on 28 nm metal layer and shows a big improvement in the process window performance. For an optimized Aerial-Image-Retargeting (AIR) recipe is very computationally efficient and its runtime doesn't consume more than 1% of the OPC flow runtime.

Yehia Hamouda, Ayman; Word, James; Anis, Mohab; Karim, Karim S.

2011-03-01

423

Patients' perspectives on high-tech home care: a qualitative inquiry into the user-friendliness of four technologies  

Microsoft Academic Search

BACKGROUND: The delivery of technology-enhanced home care is growing in most industrialized countries. The objective of our study was to document, from the patient's perspective, how the level of user-friendliness of medical technology influences its integration into the private and social lives of patients. Understanding what makes a technology user-friendly should help improve the design of home care services. METHODS:

Pascale Lehoux

2004-01-01

424

OPTIGRAMI V2 user`s guide. Forest Service general technical report (Final)  

SciTech Connect

OPTIGRAMI V2 is a computer program available for IBM compatible personal computers with 80286 and higher processors. OPTIGRAMI V2 determines the least-cost lumber grade mix required to produce a given cutting order for clear parts from rough lumber of known grades in a crosscut-first rough mill operation. It is a user-friendly integrated application that includes optimization for species graded under standard National Hardwood Lumber Association grade rules, as well as yellow-poplar and black walnut. Output information includes: gross volume of lumber required in each lumber grade, estimated total production cost, board footage of parts generated, percent yield, and range of costs within each lumber grade for which the given solution is valid.

Lawson, P.S.; Thomas, R.E.; Walker, E.S.

1996-07-25

425

Evaluating User Participation and User Influence in an Enterprise System  

ERIC Educational Resources Information Center

Does user influence have an impact on the data quality of an information systems development project? What decision making should users have? How can users effectively be engaged in the process? What is success? User participation is considered to be a critical success factor for Enterprise Resource Planning (ERP) projects, yet there is little…

Gibbs, Martin D.

2010-01-01

426

Learning Ubiquitous User Models based on Users' Location History  

Microsoft Academic Search

Recent development of location technologies enables us to obtain the location history of users. This paper proposes a new method to infer users' long-term properties from their respective lo- cation histories. Counting the instances of sensor detection for every user, we can obtain a sensor-user matrix. After generating features from the matrix, a machine learning approach is taken to automati-

Junichiro Mori; Dominik Heckmann; Yutaka Matsuo; Anthony Jameson

427

Analysis of users and non-users of smartphone applications  

Microsoft Academic Search

PurposeSmartphones facilitate the potential adoption of new mobile applications. The purpose of this research is to study users and non-users of three selected mobile applications, and find out what really drives the intention to use these applications across users and non-users.

Hannu Verkasalo; Carolina López-Nicolįs; Francisco J. Molina-Castillo; Harry Bouwman

2010-01-01

428

Mill profiler machines soft materials accurately  

NASA Technical Reports Server (NTRS)

Mill profiler machines bevels, slots, and grooves in soft materials, such as styrofoam phenolic-filled cores, to any desired thickness. A single operator can accurately control cutting depths in contour or straight line work.

Rauschl, J. A.

1966-01-01

429

Task 23 -- User`s guide to GRI-ShowFlow  

SciTech Connect

GRI-ShowFlow is a compilation of flow and transport groundwater models under one user-friendly, graphical interface in the Microsoft{reg_sign}Windows{trademark} 3.1 environment. The groundwater models as well as the interface were derived from existing codes. The motivation behind the development of GRI-ShowFlow was twofold: (1) there is a need to compare and assess various analytical and screening-level models that are being used by regulatory agencies and (2) there is a need for the nonexpert to be able to use these screening-level models and the resulting information without expert interpretation. GRI-ShowFlow was developed for use by gas industry environmental staff who may have little experience with hydrogeology or groundwater models but must be able to quickly determine whether there is sufficient chance of groundwater contamination and whether a site does or does not require a more extensive examination. Special attention was therefore given to the Help System in GRI-ShowFlow, which aids the development of the minimal amount of data required by the program and the interpretation of the resulting data. The objective of GRI-ShowFlow is to bring together the existing EPA models in a user-friendly environment and to compare them to each other as well as to new models that contain analytical solutions to three-dimensional source descriptions. A three-dimensional body will more closely reflect the shapes of contaminant sources than one- or two-dimensional geometries. In the real world, contamination sources such as landfills, storage pits, and lagoons will, after all, occupy a three-dimensional space.

NONE

1997-03-01

430

Improving the Usability of the User Interface for a Digital Textbook Platform for Elementary-School Students  

ERIC Educational Resources Information Center

Usability is critical to the development of a user-friendly digital textbook platform interface, yet thorough research on interface development based on usability principles is in short supply. This study addresses that need by looking at usability attributes and corresponding design elements from a learning perspective. The researchers used a…

Lim, Cheolil; Song, Hae-Deok; Lee, Yekyung

2012-01-01

431

Development of a Prototype Intelligent User Interface Subsystem for NASA's (National Aeronautics and Space Administration's) Scientific Database Systems.  

National Technical Information Service (NTIS)

The National Space Science Data Center (NSSDC) has initiated an Intelligent Data Management (IDM) research effort which has as one of its components the development of an Intelligent User Interface (IUI).The intent of the latter is to develop a friendly a...

W. J. Campbell, L. H. Roelofs, N. M. Short

1987-01-01

432

Implementation of harm reduction toward crack users in Brazil: barriers and achievements.  

PubMed

From 2002 to 2005, we evaluated five Brazilian harm reduction programs ran by active drug users who distributed pipes, condoms, educational material, and provided referral to crack users. System-wide barriers identified: funds discontinuation and legislation barriers toward fieldwork. Major achievements: increased access to health, social, and psychological support. Crack-cocaine users experience a plethora of health/social problems, attenuated by low-threshold and user-friendly interventions, particularly those developed by other drug users. However, a stronger political commitment is needed to face a fast growing crack-cocaine epidemic in Brazil, aiming to ensure availability/continuity of funds, implementation of large-scale interventions, outreach workers training, and proper evaluation. PMID:22428821

Domanico, Andrea; Malta, Monica

2012-04-01

433

Spud 1.0: generalising and automating the user interfaces of scientific computer models  

NASA Astrophysics Data System (ADS)

The interfaces by which users specify the scenarios to be simulated by scientific computer models are frequently primitive, under-documented and ad-hoc text files which make using the model in question difficult and error-prone and significantly increase the development cost of the model. In this paper, we present a model-independent system, Spud, which formalises the specification of model input formats in terms of formal grammars. This is combined with an automated graphical user interface which guides users to create valid model inputs based on the grammar provided, and a generic options reading module, libspud, which minimises the development cost of adding model options. Together, this provides a user friendly, well documented, self validating user interface which is applicable to a wide range of scientific models and which minimises the developer input required to maintain and extend the model interface.

Ham, D. A.; Farrell, P. E.; Gorman, G. J.; Maddison, J. R.; Wilson, C. R.; Kramer, S. C.; Shipton, J.; Collins, G. S.; Cotter, C. J.; Piggott, M. D.

2009-03-01

434

Spud 1.0: generalising and automating the user interfaces of scientific computer models  

NASA Astrophysics Data System (ADS)

The interfaces by which users specify the scenarios to be simulated by scientific computer models are frequently primitive, under-documented and ad-hoc text files which make using the model in question difficult and error-prone and significantly increase the development cost of the model. In this paper, we present a model-independent system, Spud, which formalises the specification of model input formats in terms of formal grammars. This is combined with an automated graphical user interface which guides users to create valid model inputs based on the grammar provided, and a generic options reading module which minimises the development cost of adding model options. Together, this provides a user friendly, well documented, self validating user interface which is applicable to a wide range of scientific models and which minimises the developer input required to maintain and extend the model interface.

Ham, D. A.; Farrell, P. E.; Gorman, G. J.; Maddison, J. R.; Wilson, C. R.; Kramer, S. C.; Shipton, J.; Collins, G. S.; Cotter, C. J.; Piggott, M. D.

2008-07-01

435

EIAW: Towards a Business-Friendly Data Warehouse Using Semantic Web Technologies  

NASA Astrophysics Data System (ADS)

Data warehouse is now widely used in business analysis and decision making processes. To adapt the rapidly changing business environment, we develop a tool to make data warehouses more business-friendly by using Semantic Web technologies. The main idea is to make business semantics explicit by uniformly representing the business metadata (i.e. conceptual enterprise data model and multidimensional model) with an extended OWL language. Then a mapping from the business metadata to the schema of the data warehouse is built. When an analysis request is raised, a customized data mart with data populated from the data warehouse can be automatically generated with the help of this built-in knowledge. This tool, called Enterprise Information Asset Workbench (EIAW), is deployed at the Taikang Life Insurance Company, one of the top five insurance companies of China. User feedback shows that OWL provides an excellent basis for the representation of business semantics in data warehouse, but many necessary extensions are also needed in the real application. The user also deemed this tool very helpful because of its flexibility and speeding up data mart deployment in face of business changes.

Xie, Guotong; Yang, Yang; Liu, Shengping; Qiu, Zhaoming; Pan, Yue; Zhou, Xiongzhi

436

TWEAT `95: User`s documentation update  

SciTech Connect

This report is designed to be a supplement to TWEAT`94 (PVTD-C94-05.01K Rev.1). It is intended to describe the primary features of the Ternary Waste Envelope Assessment Tool software package that have been added in FY`95 and how to use them. It contains only minimal duplication of information found in TWEAT`94 even though all features of TWEAT`94 will still be available. Emphasis on this Update is the binary plotting capability and the OWL Import modifications. Like it`s predecessors, this manual does not provide instructions for modifying the program code itself. The user of TWEAT`95 is expected to be familiar with the basic concepts and operation of the TWEAT software as discussed in TWEAT`94. Software and hardware requirements have not changed since TWEAT`94. TWEAT has now been tested using Macintosh System software versions 6.05 through 7.5.

Robertus, B.; Lambert, R.

1996-03-01

437

Learning among Critical Friends in the Instrumental Setting  

ERIC Educational Resources Information Center

The article is based on a phenomenological way of thinking about knowledge and learning and will treat the concepts of response and critical friends as ways of sharing experience in higher music education. The problem area I want to illuminate is how teachers, who educate musicians, can use and facilitate development of their students' skills…

Ferm Thorgersen, Cecilia

2014-01-01

438

Behavior Learning of Human-Friendly Robots by Symbolic Teaching  

Microsoft Academic Search

This paper deals with behavior learning of human-friendly robots by human symbolic teaching. The mobile robot has an internal model for its behavior criteria and acquires human teaching model based on the behav- ior criteria. Outputs of human teaching model are used for learning reactive motions such as collision avoidance behavior. The feature of this method is to obtain suitable

Naoyuki Kubota; Shuzo Yamaji; Fumio Kojima; Toshio Fukuda

439

Drug Abuse Prevention for You and Your Friends.  

ERIC Educational Resources Information Center

This booklet, written for adolescents, focuses on the individual's role and responsibility, both to themselves and their friends, in preventing drug abuse problems. Short statements define the influence of peer pressure on prevention, friendship, and intervention. The results of a ninth grade student survey list 22 reasons for using drugs,…

Porter, Novelli and Associates, Inc., Washington, DC.

440

Critical Friends Group for EFL Teacher Professional Development  

ERIC Educational Resources Information Center

For the best student outcomes, teachers need to engage in continuous professional development. As a result, models of teacher professional development have been developed, among which is the Critical Friends Group (CFG) technique. However, whether it works well with EFL teachers in an Asian context like Vietnam, where EFL teachers in particular do…

Vo, Long Thanh; Nguyen, Hoa Thi Mai

2010-01-01

441

Evaluation of environmentally friendly paints over weathering galvanised steel  

Microsoft Academic Search

A comparative study between a high solids paint and a traditional coat was made using electrochemical impedance spectroscopy technique, both paints were applied over weathering galvanised steel. The results indicated that the high solids paint had the better behaviour and thus represents a good environmentally friendly alternative. Previously, the optimum degree of weathering on a galvanised surface was assessed on

A Collazo; C Pérez; M Izquierdo; P Merino

2003-01-01

442

Best Friends Forever?: Race and the Stability of Adolescent Friendships  

Microsoft Academic Search

Our research uses two waves of data from the National Longitudinal Study of Adolescent Health to analyze the stability of same- and cross-race friendships. We find the following: First, interracial friendships are less stable than same-race friendships, even after controlling for a variety of contextual and dyadic characteristics, such as school racial composition and friends' similarities in attitudes and behaviors.

Jesse Rude; Daniel Herda

2010-01-01

443

Child-Friendly School Initiative in Jordan: A Sharing Experience  

ERIC Educational Resources Information Center

The purpose of this research was to report on a Child-Friendly School (CFS) initiative pilot project in Jordan, which aims at initiating the creation of CFS and to raise stakeholders' awareness of the importance of this project in promoting and implementing Child Rights Conviction (CRC) in Jordan. The study was conducted by a joint team selected…

Weshah, Hani A.; Al-Faori, Oraib; Sakal, Reham M.

2012-01-01

444

Interdisciplinary Chemistry Experiment: An Environmentally Friendly Extraction of Lycopene  

ERIC Educational Resources Information Center

A novel experiment for the extraction of lycopene from tomato paste without the use of an organic solvent is described. The experiment employs polymer, green, and analytical chemistry. This environmentally friendly extraction is more efficient and requires less time than the traditional approach using an organic solvent. The extraction is…

Zhu, Jie; Zhang, Mingjie; Liu, Qingwei

2008-01-01

445

2008 FRIENDS-OF-NCI-EGRP News Flashes  

Cancer.gov

The following is an archive of listserv announcements, or "News Flashes" sent by the Epidemiology and Genetics Research Program (EGRP) to FRIENDS-OF-NCI-EGRP LISTSERV subscribers. These occasional announcements communicate information about funding opportunities related to cancer epidemiology, grantsmanship issues, research resources, and other relevant news.

446

The Friends of Northside ISD Libraries Sets Sail  

ERIC Educational Resources Information Center

The Director of Library and Textbook services for the Northside Independent School District (NISD) Jana Knezek, had long wanted to create a Friends group and she realized how beneficial it would be to have an organization in place that could serve as an advocate for school library issues. Jana temporarily put aside that desire and participated in…

Hultgren, Joyce

2009-01-01

447

Communication Training of Relatives and Friends of Institutionalized Elderly Persons.  

ERIC Educational Resources Information Center

Describes a series of workshops for family and friends of institutionalized elderly persons designed to inform them of the nature of communication, how it is affected by the aging process, the psychological and neurological nature of communication impairments, and how to manage situations in which communication breaks down. (Author)

Shulman, Martin D.; Mandel, Ellen

1988-01-01

448

The development of recycle-friendly automotive aluminum alloys  

Microsoft Academic Search

The continuing growth of aluminum alloy usage in transportation applications, notably passenger automobiles and minivans, and the demonstrated economic benefits of recycling aluminum-rich vehicles increase the need to seriously consider the desirability of designing recycling-friendly alloys. This article focuses on that aspect of the recycling process for passenger vehicles. The goals are to illustrate the opportunities afforded by identifying and

Subodh K. Das; J. A. S. Green; J. Gilbert Kaufman

2007-01-01

449

Peer Network Overlap in Twin, Sibling, and Friend Dyads  

ERIC Educational Resources Information Center

Research suggests that sibling–peer connections are important for understanding adolescent problem behaviors. Using a novel behavioral genetic design, the current study investigated peer network overlap in 300 child–child pairs (aged 7-13 years) in 5 dyad types: monozygotic (MZ), dizygotic twins, full siblings (FSs), friend pairs, and virtual…

McGuire, Shirley; Segal, Nancy L.

2013-01-01

450

The Food Friends: Encouraging Preschoolers to Try New Foods  

ERIC Educational Resources Information Center

In response to concerns about children's eating behaviors, the Colorado Nutrition Network developed and tested Food Friends--Making New Foods Fun for Kids. The program was designed as a 12-week social marketing campaign aimed at encouraging preschool-age children to try new foods, such as Ugli Fruit, couscous, and daikon radish. Tasting novel…

Bellows, Laura; Anderson, Jennifer

2006-01-01

451

The Research on an Environment-Friendly Air Conditioning System  

Microsoft Academic Search

In this paper, some of the present environment-friendly air conditioning systems were reviewed. A new air conditioning system, named displacement ventilation system with dew point evaporative and radiation cooling was presented. The operational principle of the system was discussed. The air-handling process in different weather conditions was analyzed as well. It was found that the new system can save a

Zhang Xinghui; Hou Zhiyan

2010-01-01

452

Embracing Diversity: Toolkit for Creating Inclusive Learning-Friendly Environments  

ERIC Educational Resources Information Center

An inclusive, learning-friendly environment (ILFE) welcomes, nurtures, and educates all children regardless of their gender, physical, intellectual, socio-economic, emotional, linguistic and other characteristics. "Inclusive" in the school setting generally refers to the inclusion or children with disabilities into regular classrooms designed for…

Harris, Ray; Miske, Shirley; Attig, George

2004-01-01

453

A Practitioner Friendly and Scientifically Robust Training Evaluation Approach  

ERIC Educational Resources Information Center

Purpose: This article seeks to review the current state of workplace learning evaluation, to set out the rationale for evaluation along with the barriers that practitioners face when seeking to assess the effectiveness of training and development. Finally, it aims to propose a scientifically robust and practitioner friendly approach to evaluation.…

Griffin, Richard

2012-01-01

454

Concepts and Challenges for Environmentally Friendly En Route Operations  

NASA Technical Reports Server (NTRS)

Presented research on environmentally friendly en route traffic flow concepts incorporating models developed by basic climate research Developed an optimal contrail reduction trajectory concept. Integrated fuel flow, emissions and optimization models with FACET. Verified it against FAA emission models. Ability to conduct system level analysis of Traffic Flow Management concepts with minimal environmental impact.

Sridhar, Banavar

2010-01-01

455

Environmentally friendly corrosion preventive compounds for ground support structures  

NASA Astrophysics Data System (ADS)

The need to use environmentally friendly technologies throughout future space-related launch programs prompted a study aimed at replacing current petroleum and solvent-based corrosion preventive compounds (CPCs) with environmentally friendly alternatives. The work in this paper focused on the identification and evaluation of environmentally friendly CPCs for use in protecting flight hardware and ground support equipment from atmospheric corrosion. CPCs are used as temporary protective coatings and must survive in the aggressive coastal marine environment that exists throughout the Kennedy Space Center, Florida. The different protection behaviors of fifteen different oily film CPCs, both common petroleum-based and newer environmentally friendly types, were evaluated on various steel and aluminum substrates. CPC and substrate systems were subjected to atmospheric testing at the Kennedy Space Center's Beachside Atmospheric Corrosion Test Site, as well as cyclic accelerated corrosion testing. Each CPC also underwent physical characterization and launch-related compatibility testing. The results for the fifteen CPC systems are presented in this paper.

Montgomery, Eliza; Curran, Jerome; Calle, Luz Marina; Kolody, Mark

456

Fish: A New Computer Program for Friendly Introductory Statistics Help  

ERIC Educational Resources Information Center

All introductory statistics students must master certain basic descriptive statistics, including means, standard deviations and correlations. Students must also gain insight into such complex concepts as the central limit theorem and standard error. This article introduces and describes the Friendly Introductory Statistics Help (FISH) computer…

Brooks, Gordon P.; Raffle, Holly

2005-01-01

457

Data from the Television Game Show "Friend or Foe?"  

ERIC Educational Resources Information Center

The data discussed in this paper are from the television game show "Friend or Foe", and can be used to examine whether age, gender, race, and the amount of prize money affect contestants' strategies. The data are suitable for a variety of statistical analyses, such as descriptive statistics, testing for differences in means or proportions, and…

Kalist, David E.

2004-01-01

458

Conflict between Friends During Early Adolescence: Sources, Strategies, and Outcomes.  

ERIC Educational Resources Information Center

Friendships of early adolescence are generally accepted as having special significance for psychological development. This study was conducted to examine the sources of conflict between friends during early adolescence; to assess the social-cognitive developmental level of early adolescents; and to explore the relationships among sources of…

Spradling, Vicky Y.; And Others

459

2009 FRIENDS-OF-NCI-EGRP News Flashes  

Cancer.gov

The following is an archive of listserv announcements, or "News Flashes" sent by the Epidemiology and Genetics Research Program (EGRP) to FRIENDS-OF-NCI-EGRP LISTSERV subscribers. These occasional announcements communicate information about funding opportunities related to cancer epidemiology, grantsmanship issues, research resources, and other relevant news.

460

2011 FRIENDS-OF-NCI-EGRP News Flashes  

Cancer.gov

The following is an archive of listserv announcements, or "News Flashes" sent by the Epidemiology and Genetics Research Program (EGRP) to FRIENDS-OF-NCI-EGRP LISTSERV subscribers. These occasional announcements communicate information about funding opportunities related to cancer epidemiology, grantsmanship issues, research resources, and other relevant news.

461

Environmentally Friendly Corrosion Preventative Compounds for Ground Support Structures  

NASA Technical Reports Server (NTRS)

The need to use environmentally friendly technologies throughout future space-related launch programs prompted a study aimed at replacing current petroleum and solvent-based Corrosion Preventive Compounds (CPCs) with environmentally friendly alternatives. The work in this paper focused on the identification and evaluation of environmentally friendly CPCs for use in protecting flight hardware and ground support equipment from atmospheric corrosion. CPCs are used as temporary protective coatings and must survive in the aggressive coastal marine environment that exists throughout the Kennedy Space Center, Florida. The different protection behaviors of fifteen different oily film CPCs, both common petroleum-based and newer environmentally friendly types, were evaluated on various steel and aluminum substrates. CPC and substrate systems were subjected to atmospheric testing at the Kennedy Space Center's Beachside Atmospheric Corrosion Test Site, as well as cyclic accelerated corrosion testing. Each CPC also underwent physical characterization and launch-related compatibility testing. The results for the fifteen CPC systems are presented in this paper.

Montgomery Eliza L.; Calle, Luz, Marina; Curran, Jerome P.; Kolody, Mark R.

2013-01-01

462

Another Downside to Obesity for Teens: Fewer Friends  

MedlinePLUS

... please enable JavaScript. Another Downside to Obesity for Teens: Fewer Friends Study found rejection by normal-weight ... 15, 2014 Related MedlinePlus Pages Obesity in Children Teen Mental Health THURSDAY, May 15, 2014 (HealthDay News) -- ...

463

Peeking at the Relationship World of Infant Friends and Caregivers  

ERIC Educational Resources Information Center

This qualitative study aimed to explore how infants share and experience friendships and examine the role of infant caregivers in social and friendship experiences among infants. The data were collected through classroom observation over a semester. Findings yielded complex and rich social relationships that both infant friends and caregivers…

Shin, Minsun

2010-01-01

464

Fast and accurate automated cell boundary determination for fluorescence microscopy  

NASA Astrophysics Data System (ADS)

Detailed measurement of cell phenotype information from digital fluorescence images has the potential to greatly advance biomedicine in various disciplines such as patient diagnostics or drug screening. Yet, the complexity of cell conformations presents a major barrier preventing effective determination of cell boundaries, and introduces measurement error that propagates throughout subsequent assessment of cellular parameters and statistical analysis. State-of-the-art image segmentation techniques that require user-interaction, prolonged computation time and specialized training cannot adequately provide the support for high content platforms, which often sacrifice resolution to foster the speedy collection of massive amounts of cellular data. This work introduces a strategy that allows us to rapidly obtain accurate cell boundaries from digital fluorescent images in an automated format. Hence, this new method has broad applicability to promote biotechnology.

Arce, Stephen Hugo; Wu, Pei-Hsun; Tseng, Yiider

2013-07-01

465

A non-expert-user interface for posing signing avatars.  

PubMed

We describe a graphical user interface designed to allow non-expert users to pose 3D characters to create American Sign Language (ASL) computer animation. The interface is an important component of a software system that allows educators of the Deaf to add sign language translation, in the form of 3D character animations, to digital learning materials, thus making them accessible to deaf learners. A study indicates that users with no computer animation expertize can create animated ASL signs quickly and accurately. PMID:22789025

Adamo-Villani, Nicoletta; Popescu, Voicu; Lestina, Jason

2013-05-01

466

GVU's WWW User Surveys  

NSDL National Science Digital Library

Graphic, Visualization, & Usability Center's (GVU) WWW User Survey, from Georgia Tech, has been tracking various demographics of WWW users since January 1994. All of the surveys are available from the site. Demographic data include age, gender, location, marital status, occupations, political party, etc. Additional questions cover data privacy, censorship, security, information gathering and purchasing behavior, and a special section regarding web authoring. The survey included some 15,000 unique respondents. The results are presented in multiple forms from various summaries to graphical presentations to survey methodology. Full results and data sets are not yet posted. The press release contains various conclusions, and states that "the rate of introducing new users has slowed...[and will remain slow until the introduction of] new and inexpensive "plug and play" technologies such as Web TV or the Internet phone become widely available."

Keho, Colleen.; Pitkow, Jim.

1997-01-01

467

MERBoard User's Guide  

NASA Technical Reports Server (NTRS)

An important goal of MERBoard is to allow users to quickly and easily share information. The front-end interface is physically a large plasma computer display with a touch screen, allowing multiple people to interact shoulder-to-shoulder or in a small meeting area. The software system allows people to interactively create digital whiteboards, browse the web, give presentations and connect to personal computers (for example, to run applications not on the MERBoard computer itself). There are four major integrated applications: a browser; a remote connection to another computer (VNC); a digital whiteboard; and a digital space (MERSpace), which is a digital repository for each individual user.

Trimble, Jay; Shab, Ted; Vera, Alonso; Gaswiller, Rich; Clancy, Daniel (Technical Monitor)