Angiotensin-converting enzyme 2 (ACE2) is a terminal carboxypeptidase and the receptor for the SARS and NL63 coronaviruses (CoV). Loss of ACE2 function is implicated in severe acute respiratory syndrome (SARS) pathogenesis, but little is known about ACE2 biogenesis and activity in the airways. We report that ACE2 ...

The human coronaviruses (CoVs) severe acute respiratory syndrome (SARS)-CoV and NL63 employ angiotensin-converting enzyme 2 (ACE2) for cell entry. It was shown that recombinant SARS-CoV spike protein (SARS-S) downregulates ACE2 expression and thereby promotes lung injury. Whether NL63-S exerts a similar activity is ...

Angiotensin converting enzyme 2 (ACE2) cleaves angiotensin II (Ang II) to form Ang-(1-7). Here we examined whether soluble human recombinant ACE2 (rACE2) can efficiently lower Ang II and increase Ang-(1-7), and whether rACE2 can ...

Angiotensin-converting enzyme (ACE) 2 is a homolog to the carboxypeptidase ACE, which generates angiotensin II, the main active peptide of renin-angiotensin system (RAS). After the cloning of ACE2 in 2000, three major ACE2 functions have been described so far. First ACE2 ...

Adipose tissue expresses components of the renin-angiotensin system (RAS). Angiotensin converting enzyme (ACE2), a new component of the RAS, catabolizes the vasoconstrictor peptide ANG II to form the vasodilator angiotensin 1-7 [ANG-(1-7)]. We examined whether adipocytes express ACE2 and its regulation by ...

ADAM17, also known as tumor necrosis factor ?-converting enzyme, is involved in the ectodomain shedding of many integral membrane proteins. We have previously reported that ADAM17 is able to mediate the cleavage secretion of the ectodomain of human angiotensin-converting enzyme 2 (ACE2), a functional receptor for the severe acute ...

Severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in 2002 as an important cause of severe lower respiratory tract infection in humans, and in vitro models of the lung are needed to elucidate cellular targets and the consequences of viral infection. The SARS-CoV receptor, human angiotensin 1-converting enzyme 2 (hACE2), ...

It is believed that a novel coronavirus, severe acute respiratory syndrome coronavirus (SARS-CoV), was passed from palm civets to humans and caused the epidemic of SARS in 2002 to 2003. The major species barriers between humans and civets for SARS-CoV infections are the specific interactions between a defined receptor-binding domain (RBD) on a viral spike protein and its host ...

It is believed that a novel coronavirus, severe acute respiratory syndrome coronavirus (SARS-CoV), was passed from palm civets to humans and caused the epidemic of SARS in 2002 to 2003. The major species barriers between humans and civets for SARS-CoV infections are the specific interactions between a defined receptor-binding domain (RBD) on a viral spike protein and its host ...

It is believed that a novel coronavirus, severe acute respiratory syndrome coronavirus (SARS-CoV), was passed from palm civets to humans and caused the epidemic of SARS in 2002 to 2003. The major species barriers between humans and civets for SARS-CoV infections are the specific interactions between a defined receptor-binding domain (RBD) on a viral spike protein and its host ...

Severe acute respiratory syndrome (SARS) is caused by the SARS-associated coronavirus (SARS-CoV), which uses angiotensin-converting enzyme 2 (ACE2) as its receptor for cell entry. A group of SARS-like CoVs (SL-CoVs) has been identified in horseshoe bats. SL-CoVs and SARS-CoVs share identical genome organizations and high sequence ...

Severe acute respiratory syndrome (SARS) is caused by the SARS-associated coronavirus (SARS-CoV), which uses angiotensin-converting enzyme 2 (ACE2) as its receptor for cell entry. A group of SARS-like CoVs (SL-CoVs) has been identified in horseshoe bats. SL-CoVs and SARS-CoVs share identical genome organizations and high sequence ...

OBJECTIVEDiabetic nephropathy is one of the most common causes of end-stage renal failure. Inhibition of ACE2 function accelerates diabetic kidney injury, whereas renal ACE2 is downregulated in diabetic nephropathy. We examined the ability of human recombinant ACE2 ...

This report is limited in scope to consideration of the problems caused by vortex shedding from flexible, bluff cylinders in steady current flows, as these problems apply to the OTEC cold water pipe. In particular, the steady deflections caused by the amp...

Aug 30, 2010 ... ACE-2 North Atlantic Regional Aerosol Characterization Experiment. June 16 - July 25, 1997. + ACE-2 Home � + Data � + Presentations ...

Nov 8, 2004 ... ACE-2 North Atlantic Regional Aerosol Characterization Experiment ... Scattering Albedos: TARFOX and ACE-2 Results and Their Relation to ...

Haflidi Jonsson (Naval Postgraduate School, Monterey, CA 93943) ... In the ACE 2 program the solar radiant fluxes were measured on the Pelican aircraft and ...

Students observe how water acts differently when placed on hydrophilic and hydrophobic surfaces. They determine which coatings are best to cause surfaces to shed water quickly or reduce the �fogging� caused by condensation.

NASA Study Sheds Light on Ozone Hole Chemistry. April 28, 2010 ... chlorine and bromine from human-produced compounds cause the nearly total destruction of ...

NASA Study Sheds Light on Ozone Hole Chemistry. 04.28.10 ... chlorine and bromine from human-produced compounds cause the nearly total destruction of ozone ...

This report focuses on the unsteady flow in compressors and turbines caused by shed wakes from upstream blade row airfoils as these wakes impinge on and change the inlet conditions for a downstream blade row. Three sets of experiments were available where...

Rationale: It has been proposed that an activated renin angiotensin system (RAS) causes an imbalance between the vasoconstrictive and vasodilator mechanisms involving the pulmonary circulation leading to the development of pulmonary hypertension (PH). Recent studies have indicated that angiotensin-converting enzyme 2 (ACE2), a member ...

There is evidence that angiotensin-converting enzyme 2 (ACE2) is cardioprotective. To assess this in the post-myocardial infarction (MI) heart, we treated adult male Sprague-Dawley rats with either placebo (PL) or C16, a selective ACE2 inhibitor, following permanent coronary artery ligation or sham ...

Pulp mill is one of the heavy industries that consumes large amount of electricity in its production. In particular, the breakdown of the generator would cause other generators to be overloaded. Thus, load shedding scheme is the best way in handling such condition. Selected load will be shed under this scheme in order to protect the ...

... movement of the grain boundaries. Grain boundary migration can cause cavitated boundaries to shed their voids into the matrix. ...

is caused by the bacteria Coxiella burnetii. The bacteria affects sheep, goats, cattle, dogs, cats, birds, rodents, and ticks, as well as some other animals. Infected animals shed...

are making a special effort to minimize any distortion of the record caused by urban heat-island effects as they research global warming. It is recognized that recorded...

Apr 21, 2011 ... Cytomegalovirus (CMV): CMV is another herpes virus and it is shed in urine after reactivation. In addition to causing very serious congenital ...

In this work, the author interprets the intelligence environment of political, military and information empires. This contribution sheds light on the cause of enduring intelligence collection deficits that afflict the center of such empires, and that can ...

... caused by weakness in the wall of the aorta, the largest artery in the body. The aneurysm ... aortic dissection -- a usually fatal tear in the aorta. The new findings were published June 16 in ...

Lesson learned: Do not let anyone or anything cause you to hurry. That is when mistakes happen that can lead to accidents. Shed a Little Light and Avoid the ...

This complex behavior can cause soil to behave like a liquid under certain ... MGM is shedding light on the behavior of fine-grain materials under low ...

This paper describes the results of investigations into the cause of certain flashovers which occurred to horizontally mounted insulators in HVDC stations. Insulators having various shed shapes were subjected to contamination and wet tests under horizontally and vertically mounted conditions. Non-uniform wetting was identified as the main ...

Nov 8, 2004 ... This is free software. http://www.adobe.com. Clear sky closure studies of lower tropospheric aerosol and water vapor during ACE-2 using ...

Nov 8, 2004 ... This is free software. http://www.adobe.com. Airborne solar radiant flux measurements during ACE-2 - Bergstrom et al. ...

... Sheds Light on Cause of Brain Deficits in HIV Patients Virus can weaken blood-brain barrier and ... Preidt Tuesday, June 28, 2011 Related MedlinePlus Pages HIV/AIDS Living with HIV/AIDS TUESDAY, June 28 ( ...

An optimization algorithm for a load shedding system is presented. The Israeli power system is not interconnected with any neighboring system. Being a relatively small system, an outage of a single generating unit may cause blackouts. One way of preventing this is an underfrequency load shedding system, which is composed of several ...

... caninum is the most frequently diagnosed cause of abortion in cattle throughout the world (Dubey, 1999). The ... is circumstantial evidence that epidemic N. caninum�associated abortions in cattle are caus...

The cause of the phenomenon of steady asymmetric flow on cones at moderately high angles of attack is the subject of this investigation. At very higher angles of attack, the flow will become unsteady with a Karman vortex street being shed downstream. This...

Students observe how water acts differently when placed on hydrophilic and hydrophobic surfaces. Students determine which type of coatings are best to use to cause a surface to shed water quickly or to reduce the �fogging� caused by condensation.

Male pattern baldness Female pattern baldness Causes A sudden physical or emotional stress may cause one-half to three-quarters of the hair throughout your scalp to shed (called...

Salmonella is a major cause of foodborne illness in humans and causes over a third of all cases of gastroenteritis in the United States. Human foodborne outbreaks due to Salmonella have been traced to milk, beef, pork, and poultry. Fecal contamination of the carcass and hide is thought to be a maj...

ORIGINAL ARTICLE Angiotensin-converting enzyme 2 (ACE2) proteins of different bat species confer- converting enzyme 2 (ACE2) protein, a known SARS-CoV receptor, from a horseshoe bat was unable to act as a func- tional receptor for SARS-CoV. Here, we extended our previous study to ACE2 molecules from seven

Q fever is a zoonosis caused by Coxiella burnetii, a bacterium largely carried by ruminants and shed into milk, vaginal mucus, and feces. The main potential hazard to humans and animals is due to shedding of bacteria that can then persist in the environment and be aerosolized. The purpose of this study was to evaluate ...

Q fever is a zoonosis caused by Coxiella burnetii, a bacterium largely carried by ruminants and shed into milk, vaginal mucus, and feces. The main potential hazard to humans and animals is due to shedding of bacteria that can then persist in the environment and be aerosolized. The purpose of this study was to evaluate ...

BackgroundIt has been recently reported that major pathogens Staphylococcus aureus and Pseudomonas aeruginosa accelerate a normal process of cell surface syndecan-1 (Synd1) ectodomain shedding as a mechanism of host damage due to the production of shedding-inducing virulence factors. We tested if acceleration of Synd1 shedding takes ...

Equipment overloads in an underground transmission network are caused by unscheduled outages. Repairs or replacements of damaged cables and/or transformers in urban areas are inherently difficult and time-consuming. Therefore, for overloads greatly in excess of short-time ratings, speed of load shedding is of paramount importance. Under such conditions, ...

Cell culture experiments often employ the use of culture media that contain fetal calf serum (FCS). The angiotensin peptides angiotensin II and angiotensin 1�7 have opposing effects with angiotensin converting enzyme 2 (ACE2) being the enzyme predominantly responsible for generating angiotensin 1�7 from angiotensin II. The effect of FCS on angiotensin ...

INTRODUCTION: : Ace b/l polymorphism in rats is associated with differential tissue angiotensin-converting enzyme (ACE) expression and activity, and susceptibility to renal damage. Same polymorphism was recently found in outbred Wistar rat strain with b allele accounting for higher renal ACE, and provided a model for studying renin-angiotensin-aldosterone system (RAAS) response behind the innate ...

Mutations in the RAM network genes, including CBK1, MOB2, KIC1, HYM1, and TAO3, cause defects in bud site selection, asymmetric apical growth, and mating projections. Additionally, these mutants show altered colony morphology, cell separation defects, and reduced CTS1 expression, phenotypes also seen by mutating the Ace2 transcription factor. We show that an ACE2 multicopy ...

Congenital cytomegalovirus (CMV) infections are a leading cause of sensorineural hearing loss (SNHL) and neurological impairment. Congenital transmission of CMV can occur with maternal primary infection, reactivation, or reinfection during pregnancy. We reviewed studies of CMV shedding in bodily fluids (defined as CMV detected by culture or CMV DNA ...

This paper discusses flow measurement by vortex shedding meters. Vortex flowmeters measure the flow of fluids in pipelines by monitoring induced vortices caused by the fluid impinging on a nonstreamlined body. Vortex meters have been available commercially from several manufacturers for a number of years. Acceptance was slow, but the paper emphasizes that ...

The Loop Current (LC) is known to shed eddies at irregular intervals from 3 to 17 months. The causes of this irregularity have not, however, been adequately identified previously. We examine the effects of various types of external forcing on shedding with a model of the western North Atlantic Ocean (96�-55�W, 6�-50�N). We ...

Aspergillus fumigatus causes serious and frequently fatal infections in immunocompromised patients. To investigate the regulation of virulence of this fungus, we constructed and analysed an A. fumigatus mutant that lacked the transcription factor Ace2, which influences virulence in other fungi. The Deltaace2 mutant had dysmorphic ...

SummaryAspergillus fumigatus causes serious and frequently fatal infections in immunocompromised patients. To investigate the regulation of virulence of this fungus, we constructed and analyzed an A. fumigatus mutant that lacked the transcription factor Ace2, which influences virulence in other fungi. The ?ace2 mutant had dysmorphic ...

Severe acute respiratory syndrome (SARS) is a newly emerged infectious disease that caused pandemic spread in 2003. The etiological agent of SARS is a novel coronavirus (SARS-CoV). The coronaviral surface spike protein S is a type I transmembrane glycoprotein that mediates initial host binding via the cell surface receptor angiotensin-converting enzyme 2 ...

Severe acute respiratory syndrome (SARS) is caused by a newly emerged coronavirus (CoV) designated SARS-CoV. The virus utilizes angiotensin-converting enzyme 2 (ACE2) as the primary receptor. Although the idea is less clear and somewhat controversial, SARS-CoV is thought to use C-type lectins DC-SIGN and/or L-SIGN (collectively ...

Aim:? Angiotensin-converting enzyme 2 (ACE2) is a type I membrane protein that antagonizes the action of angiotensin II. Because of the need for invasive kidney biopsy, little is known about the role of renal ACE2 in human kidney diseases. The authors studied if urinary ...

Beef carcass contamination is a direct result of pathogen transfer from cattle hides harboring organisms such as enterohemorrhagic Escherichia coli. Hide contamination occurs from direct and indirect fecal contamination in cattle production and lairage environments. In each of these environments, individual animals shedding E. coli O157:H7 at high levels (>10(4) CFU/g of ...

Research, development, and demonstration projects on microgrids have been progressed in many countries. Furthermore, microgrids are expected to introduce into power grids as eco-friendly small-scale power grids in the near future. Load-shedding is a problem not avoided to meet power balance between power supply and power demand to maintain specific frequency such as 50 Hz or ...

in this issue shed light on the likely causes of the drought and its conse- quences for atmospheric dust) report the most comprehensive mod- eling study to date of the ocean temperature scenario. The authors

Johne¿s disease is caused by Mycobacterium avium subsp. paratuberculosis (MAP) infection and results in economic losses in dairy industry. To control MAP transmission in herds, test-based culling has been recommended and immediate culling of high shedding animals is typically implemented. In this st...

The objectives of this study were to provide current information on the prevalence of schistosomiasis throughout Egypt, to establish trends in the prevalence of schistosomiasis in order to shed light on the potential changes caused by the Aswan High Dam, ...

The objectives of this study were to provide current information on the prevalence of schistosomiasis throughout Egypt, to establish trends in the prevalence of schistosomiasis in order to shed light on the potential changes caused by the Aswan High Dam, and to determine correlat...

It has been widely reported in the open literature that large segmented and axisymmetric Solid Rocket Motors (SRM) are subject to pressure oscillations caused by vortex shedding at annular restrictors or cavities in the grain, and acoustic feedback result...

This thesis deals with an experimental investigation of vortex induced vibrations of a circular cylinder. The purpose of the experiment was to identify the influence from a controlled disturbance of the cylinder motions on the response caused by vortex sh...

... is the leading cause of food-borne bacterial gastroenteritis in humans in the United States. Infectious bursal ... el Campylobacter jejuni es la principal causa de gastroenteritis bacterianas de origen al...

The overall objective of this thesis is to shed light on the causes for and recurrence of such terrorist phenomena as the London transit bombings. The thesis makes three central claims: that a British policy of multiculturalism enables the actions of a ne...

This thesis proposes to shed light on the causes for and recurrence of such terrorist phenomena as the London transit bombings. The thesis makes three central claims: that a British policy of multiculturalism enables the actions of a new generation of 'ho...

Sometimes the key to solving a medical problem turns up in unexpected places. For example, new discoveries about a fish's mating ritual may shed light on a cause of hearing loss in humans. This Science Update explores the correlation between levels of estrogen in female and sensitivity of hearing.

Sodium leak accident of MONJU was caused high cycles fatigue damage of thermometer well by flow-induced vibration. It was due to the symmetric vortex shedding which was occurred rear flow of thermometer well. So, Thermometer wells installed in primary and...

The timing of seasonal events such as flowering and migration is changing as the climate warms, reshuffling the order in which such events take place each year. Now research sheds light on the causes of changes in the timing of butterfly emergence.

with the classical electromagnetic mass theory [1]- [6] sheds some light on the nature of the force acting of strength g in the framework of general relativity and the classical electromagnetic mass theory in turn are caused by the average anisotropic velocity of light in N g . Thus the classical

Human angiotensin-converting enzyme 2 (ACE2) is a functional receptor for SARS coronavirus (SARS-CoV). Here we identify the SARS-CoV spike (S)-protein-binding site on ACE2. We also compare S proteins of SARS-CoV isolated during the 2002-2003 SARS outbreak and during the much less severe 2003-2004 outbreak, and from palm civets, a possible source of ...

Angiotensin (Ang) converting enzyme (ACE) 2 cleaves Ang-II into the vasodilator peptide Ang-(1-7), thus acting as a pivotal element in balancing the local effects of these peptides. ACE2 has been identified in various tissues and is supposed to be a modulator of cardiovascular function. Decreases in ACE2 expression ...

Many types of marine structures are susceptible to vortex-excited oscillations. These include the risers and conductor tubes that are employed in offshore drilling and production, deep water pipelines, and members of jacketed structures. Deepwater pile installation and driving operations also have been hampered by problems arising from vortex shedding. A discussion is given in ...

9Goddard Environmental Science and Technology Center, University of Maryland Baltimore County, and NASA Goddard Space Flight Center, Greenbelt, MD ...

stability of Saharan dust optical properties has been observed. Volume size distributions at ... In this work we investigate aerosol optical properties of ...

Page 1. Measurements of the Aerosol Light-Scattering Coefficient at Ambient and 85% Relative Humidity on the ONR Pelican During ACE-2 ...

... Title : Measurements of the Aerosol Light-Scattering Coefficient at Ambient and 85% Relative Humidity on the ONR Pelican During ACE-2. ...

Measurements of Aerosol Optical Depth Spectra during ACE-2. Presented at the Fifth International Aerosol Conference, Edingburgh, Scotland,14-18, ...

Raccoon dog is one of the suspected intermediate hosts of severe acute respiratory syndrome coronavirus (SARS-CoV). In this study, the angiotensin-converting enzyme 2 (ACE2) gene of raccoon dog (rdACE2) was cloned and sequenced. The amino acid sequence of rdACE2 has identities of 99.3, 89.2, 83.9 and 80.4 % to ACE2 ...

BackgroundRight ventricular (RV) dysfunction is a complication of pulmonary hypertension and portends a poor prognosis. Pharmacological therapies targeting RV function in pulmonary hypertension may reduce symptoms, improve hemodynamics, and potentially increase survival. We hypothesize that recombinant human angiotensin-converting enzyme 2 (rhACE2) will ...

Jul 20, 2002 ... This is free software. http://www.adobe.com. Airborne solar radiant flux measurements during ACE-2 - Bergstrom et al. ...

The effector functions responsible for resolution of shedding in mice orally inoculated with the murine rotavirus strain EDIM were identified in B-cell-deficient and normal BALB/c mice after monoclonal antibody (MAb) depletion of CD4 and CD8 cells. When depleted of CD8 cells, B-cell-deficient muMt mice resolved their infections more slowly than nondepleted animals, but CD4 ...

Pre-eclampsia is associated with trophoblast shedding-deportation and endothelial cell dysfunction. Anti-phospholipid autoantibodies increase a women's risk factor of developing pre-eclampsia. In this study we examined the hypothesis that anti-phospholipid antibodies alter the number and nature of trophoblasts shed from the placenta, and that phagocytosis ...

Shedding of the extracellular domain of cytokine receptors allows the diffusion of soluble receptors into the extracellular space; these then bind and neutralize their cytokine ligands, thus dampening inflammatory responses. The molecular mechanisms that control this process, and the extent to which shedding regulates cytokine-induced microvascular ...

Shedding of the extracellular domain of cytokine receptors allows the diffusion of soluble receptors into the extracellular space; these then bind and neutralize their cytokine ligands, thus dampening inflammatory responses. The molecular mechanisms that control this process, and the extent to which shedding regulates cytokine-induced microvascular ...

Vortex shedding frequency caused by the protrusion of inhibitors into the flow field of a solid rocket motor is investigated by experimental and mathematical models. The time dependent Navier-Stokes equations are solved using a finite difference technique assuming incompressible, two-dimensional flow under both laminar and turbulent flow conditions. For ...

Although, apparently flow-induced vibrations represent a canonical problem, a complete understanding of the fluid-structure mechanism of interaction has not yet been achieved. One of the issues associated with flow induced vibrations stems from the vortex shedding phenomenon. It is well known that vortex streets are formed in the wake of bluff bodies over a wide range of ...

Airflow over a vertical flat plate is investigated as a function of Reynolds number, using Large Eddy Simulation. It is generally known that the structure of the wake, behind a bluff body, exhibits very complex turbulent flow patterns. In many practical applications the bluff bodies are flexible structures and this characteristic enables them to respond to the aerodynamic loads. The ...

The vortex shedding in the wake behind linearly tapered circular cylinders has been considered for the two taper ratios 75:1 and 100:1. The Reynolds number based on the velocity of the incoming flow and the largest diameter was in the range from 130 to 180. The low Reynolds number assured that laminar flow prevailed in the entire flow field. The full unsteady three-dimensional ...

Combustion instabilities are a major problem in large solid rocket boosters. They are responsible for exciting undesirable oscillations in the propellant burn rate. It is believed that vortex shedding from upstream inhibitors is one of the phenomena responsible for the onset of these instabilities. Vortex shedding frequencies are time dependent due to the ...

In 1996 the NASA Ames Airborne Tracking Sunphotometers (AATS) began a decade of campaigns with major focus on tropospheric aerosols over the oceans, including comparisons to spaceborne retrievals. (This followed an 11-year period starting in 1985 that focused primarily on studies of stratospheric aerosols, smoke plumes, and atmospheric correction of land imagery.) Bridging the gap between coastal, ...

SARS coronavirus (SARS-CoV) emerged in 2002 as an important cause of severe lower respiratory tract infection in humans and in vitro models of the lung are needed to elucidate cellular targets and the consequences of viral infection. The severe and sudden onset of symptoms, resulting in an atypical pneumonia with dry cough and persistent high fever in cases of severe acute ...

SARS coronavirus (SARS-CoV) emerged in 2002 as an important cause of severe lower respiratory tract infection in humans and in vitro models of the lung are needed to elucidate cellular targets and the consequences of viral infection. The severe and sudden onset of symptoms, resulting in an atypical pneumonia with dry cough and persistent high fever in cases of severe acute ...

Johne's disease is caused by Mycobacterium avium subsp. paratuberculosis (MAP) infection and results in economic losses in the dairy industry. To control MAP transmission in herds, test-based culling has been recommended and immediate culling of high shedding animals is typically implemented. In this study, we quantified the effects of MAP control in US ...

BackgroundShiga toxin producing Escherichia coli (STEC) are an important cause of human gastro-enteritis and extraintestinal sequelae, with ruminants, especially cattle, as the major source of infection and reservoir. In this study, the fecal STEC shedding of 133 dairy cows was analyzed over a period of twelve months by monthly sampling with the aim to ...

Kaposi sarcoma-associated herpesvirus (KSHV, also called Human herpesvirus 8 or HHV8) is a ?-2 herpesvirus that causes Kaposi sarcoma. KSHV seroprevalence rates vary geographically with variable rates recorded in different sub Sahara African countries, suggesting that effects of genetic and/or environmental factors may influence the risk of infection. One study conducted in ...

Kaposi sarcoma-associated herpesvirus (KSHV, also called Human herpesvirus 8 or HHV8) is a ?-2 herpesvirus that causes Kaposi sarcoma. KSHV seroprevalence rates vary geographically with variable rates recorded in different sub Sahara African countries, suggesting that effects of genetic and/or environmental factors may influence the risk of infection. One study conducted in ...

, David A. Ostrov Abstract--Angiotensin-converting enzyme 2 (ACE2) is considered an important therapeutic provided the basis for a novel molecular docking approach in an attempt to identify ACE2 inhibitors molecules were screened by in silico molecular docking. In this structure�activity relation study

Vortex-shedding patterns behind a step-cylinder in uniformly shear flow for Reynolds numbers between 152 and 674 were studied using flow visualization and laser Doppler velocimetry. The results were analyzed using spectral analysis and the wavelet transform. The effect of shearing on vortex shedding was found to be significant. As in uniform flow, the ...

In cardiac tissue, during partial blockade of the membrane sodium channels, or at high frequencies of excitation, inexcitable obstacles with sharp edges may destabilize the propagation of electrical excitation waves, causing the formation of self-sustained vortices and turbulent cardiac electrical activity. The formation of such vortices, which visually resembles vortex ...

Fifty residential electric water heaters and 150 new residential clothes dryers were modified to respond to signals received from underfrequency, load-shedding appliance controllers. Each controller monitored the power-grid voltage signal and requested that electrical load be shed by its appliance whenever electric power-grid frequency fell below 59.95 Hz. ...

Varicella zoster virus (VZV) causes varicella (chickenpox), after which virus becomes latent in ganglia along the entire neuraxis. Virus reactivation produces zoster (shingles). Infectious VZV is found in vesicles of patients with zoster and varicella, but virus shed in the absence of disease has not been documented. VZV DNA was previously detected in ...

The mechanism that leads to lightning is complicated and not well understood. That it's not well understood isn't surprising, as this is often the case when going from scientific models to the real world. Even so, we can paint a reasonable picture of what happens if we understand a few basics about static electricity. This articles helps to shed light on what ...

Oxidative stress in the central nervous system mediates the increase in sympathetic tone that precedes the development of hypertension. We hypothesized that by transforming Angiotensin-II (AngII) into Ang-(1�7), ACE2 might reduce AngII-mediated oxidative stress in the brain and prevent autonomic dysfunction. To test this hypothesis, a relationship ...

The endothelial glycocalyx has been identified as a barrier to transvascular exchange of fluid, macromolecules, and leukocyte-endothelium (EC) adhesion during the inflammatory process. Shedding of glycans and structural changes of the glycocalyx have been shown to occur in response to several agonists. To elucidate the effects of glycan shedding on ...

The purpose of this study was to develop a sheep model to investigate reproduction, transmission, and shedding of Escherichia coli O157:H7 in ruminants. In addition, we investigated the effect of diet change on these parameters. Six groups of twin lambs given oral inoculations of 10(5) or 10(9) CFU of E. coli O157:H7 and their nondosed mothers were monitored for colonization ...