Acetazolamide increases cerebral blood flow. The generalized and regional changes in blood flow after administration of acetazolamide were evaluated by the xenon-133 inhalation technique in a series of patients with subacute or chronic focal cerebral ischemia. Acetazolamide augmented interhemispheric asymmetry of cerebral blood flow in ...

Abstract BACKGROUND: Many patients with obstructive sleep apnea syndrome (OSA) are unable or not willing to use CPAP therapy when traveling to the mountains for work or recreation although they risk pronounced hypoxemia and exacerbation of sleep apnea. Since the treatment of OSA at altitude has not been established we tested the hypothesis that ...

cortex of eight rats at baseline and after acetazolamide challenge. Trigeminal nerve stimulation.49 � 0.03 mL � min-1 � mL-1 at rest, after acetazolamide challenge, and during trigeminal nerve branch of the trigeminal nerve was stimulated with two stainless steel electrodes. The cathode

Carotid balloon test occlusion (BTO) is used to assess the collateral circulation and cerebrovascular reserve in patients in whom carotid artery occlusion is contemplated. Eight patients in whom the test was successful were evaluated with perfusion computed tomography (CT) in the resting state and after acetazolamide challenge. Three ...

Acetazolamide is a potent inhibitor of the reversible hydration of CO(2) catalyzed by the enzyme carbonic anhydrase and is commonly used to increase cerebral blood flow e.g. in order to estimate cerebrovascular reserve. However it is not known whether acetazolamide may positively affect the excitability of neurons in the brain in�vivo or cortical ...

Stimulation of Calu-3 epithelia with 7,8-benzoquinoline, under short circuit current conditions, produced a current increase that was completely accounted for by the net flux of chloride, measured simultaneously with 36Cl-. Nevertheless the current stimulated by 7,8-benzoquinoline was sensitive to acetazolamide, which caused up to 50 % ...

The acetazolamide (ACZ) challenge test is a useful clinical tool and a reliable predictor of critically reduced perfusion. In patients with chronic steno-occlusive disease, the ability to maintain normal cerebral blood flow by reducing vascular resistance secondary to autoregulatory vasodilation is compromised. Identification of the presence and degree of ...

Cerebrovascular disease is one of the leading causes of death, and approximately 50% of survivors have a residual neurologic deficit and greater than 25% require chronic care. Cerebrovascular reserve capacity (CVRC) describes how far cerebral perfusion can increase from a baseline value after stimulation. High blood pressure is the most important independent risk factor for ...

Summary: The purpose of this paper was to evaluate the effects of acetazolamide on cerebral blood flow (CBF) measured by [O-15]H2O positron emission tomography (PET) during balloon test occlusion (BTO) of the internal carotid artery (ICA). [O-15]H2O PET cerebral blood flow studies were completed in 20 patients undergoing BTO CBF determinations were ...

The role of the ophthalmic artery (OA) as a collateral to the cerebral circulation in carotid occlusive disease is somewhat controversial. The aim of this study was to assess the importance of this collateral by comparing the results of transorbital Doppler ultrasonography and regional cerebral blood flow measurements using SPECT and Xenon-133 inhalation in 41 patients with unilateral high-grade ...

Twenty chemicals that were reported to act as anion transport inhibitors, cation transport inhibitors, and inhibitors of carbonic anhydrase activity were tested at a 1% concentration (wt:wt) for their effects upon the biological activity of the gypsy moth, Lymantria dispar (L.), nucleopolyhedrovirus (LdMNPV). Among the five anion transport inhibitors ...

...2011-04-01 2011-04-01 false Sterile sodium acetazolamide. 522.44 Section 522...NEW ANIMAL DRUGS § 522.44 Sterile sodium acetazolamide. (a) Specifications. Sterile sodium acetazolamide contains...

21 Food and Drugs 6 2010-04-01...2010-04-01 false Sterile sodium acetazolamide. 522.44 ...DRUGS § 522.44 Sterile sodium acetazolamide. (a) Specifications. Sterile sodium acetazolamide contains...

... acute mountain sickness: a prospective, double-blind, randomized, ... Table 2. Effect of lectures on the understanding of acetazolamide's ( ... ...

... Title : Effect of Acetazolamide on Leg Endurance Exercise at Sea Level and Simulated Altitude. Descriptive Note : Journal article. ...

... Title : Effect of Acetazolamide on Isolated Quadriceps Muscle Endurance Performance at Sea Level and During Acute Altitude Exposure. ...

... Accession Number : ADA168074. Title : Acetazolamide and ADH, Renin, Aldosterone, and Water Electrolytes at 4100 M in Man,. ...

... Accession Number : AD0287075. Title : ADDITIVE EFFECTS OF ACETAZOLAMIDE AND FAT EMULSION ON THE AA B(CO2) DIFFERENCE. ...

The same protocol was used three times to produce a paralytic episode in a typical case of periodic familial paralysis with hypokalemia. This consisted of an effort together with a perfusion of hypertonic glucose serum and insulin. The first test provoked an attach of hypokalemic tetraplegia. The second test, two months after treatment with 500 mg daily of ...

Increased chemosensitivity to hypoxia and hypercapnia, together with a prolonged circulatory time, are the main determinants of Cheyne-Stokes (C-S) respiration in heart failure. To evaluate the effect of acetazolamide, a carbonic anhydrase inhibitor, on chemosensitivity and respiratory dynamics in patients with heart failure with C-S respiration, 12 patients (mean age 62 � 9 ...

We have studied regional cerebral blood flow (= test) and reactivity of acetazolamide injection (= retest) in 20 patients who had presented transient ischemic attacks (TIA). The cerebral blood flow was measured by the atraumatic Xenon 133 inhalation method and single photon emission tomography using a specially dedicated tomograph (TOMOMATIC 64), allowing ...

... frequent in porters taking acetazolamide than in the placebo group (P = .0001), but there were no serious side effects. Conclusions.�Acetazolamide was tolerable, but impractical for the ... ...

Lung carbonic anhydrase (CA) permits rapid pH responses when changes in regional ventilation or perfusion alter airway and alveolar PCO2. These pH changes affect airway and vascular resistances and lung compliance to optimize the balance of regional ventilation (VA) and perfusion (Q) in the lung. To test the hypothesis that these or other CA-dependent mechanisms contribute to ...

In vivo studies using pentobarbital sodium-anesthesized dogs were performed to investigate whether a transport pathway for pyruvate and lactate is present in the exocrine pancreas. Concentrations of both acids were measured in peripheral blood and pancreatic juice before and after intravenous 15-min administration of 2.25 mmol/kg DL-lactate, superimposed on continuous intravenous infusion of 3 U X ...

Acetazolamide (ACZ) was used to stimulate the cerebral vasculature on ten healthy volunteers to assess the cerebral vasomotor reactivity (CVR). We have combined near infrared spectroscopy (NIRS), diffuse correlation spectroscopy (DCS) and transcranial Doppler (TCD) technologies to non-invasively assess CVR in real-time by measuring oxy- and ...

1. The ionic mechanism involved in Ca(2+)-stimulated electrolyte transport in cultured equine sweat gland epithelial cells was studied using the short-circuit current (ISC) technique. 2. Microscopy revealed that the cultured cells grown on Millipore filters formed polarized monolayers with tight junctions. Monolayers exhibited a mean transepithelial resistance of 333.9 +/- ...

Blood lactate concentrations were measured in 18 normal subjects at the end of an exercise test designed to maintain heart rate at 85% of maximum for 15 minutes. Blood lactate concentrations were reduced at high altitude (4846 m) and correlated positively with basal pH and negatively with basal Pa,O2 levels. Blood lactate concentrations tended to be lower in those subjects on ...

The growth hormone stimulation test is usually performed to identify if hGH (human growth hormone) is deficient. The test is performed ...

Three patients, two women and one man, aged 56-70 year (mean 59 years) with modest neurological deficits and bilateral occlusion of the common carotid arteries initially identified by duplex scanning and angiography were followed by repeated clinical and transcranial Doppler examination (TCD) over 6.5 years. Vasomotor reactivity (VMR) was tested by combined examination of TCD ...

This review discusses the impact of recent publications on pathophysiologic concepts and on practical aspects of acute mountain sickness (AMS). Magnetic resonance imaging studies do not provide evidence of total brain volume increase nor edema within the first 6 to 10 h of exposure to hypoxia despite symptoms of AMS. After 16 to 32 h at about 4500 m, brain volume increases by 0.8% to 2.7%, but ...

Episodic ataxia type 2 (EA2) is an autosomal dominantly inherited neurological disorder. Patients have CACNA1A gene mutations resulting in truncation or single amino acid changes in the pore-forming subunit of Ca(v)2.1 (P/Q-type) Ca(2+) channels. These neuronal channels mediate synaptic neurotransmitter release. EA2 symptoms are thought to result from disturbed neurotransmission at cerebellar and ...

... Sera tested against purified human and rat CYP's ... Lymphocyte Stimulation Test (LST) in ADR's ... What are the right durations and doses for testing? ...

... Title : Flight Test Techniques. ... Keywords: Flight tests; Flight stimulation; Avionics; Computer systems programs; Data processing; Cost engineering. ...

Grasp and release has been provided to both upper extremities of subjects with tetraplegia using percutaneous and fully implanted stimulation. This is to determine quantitatively the performance of these subjects in three bimanual tests using two handed stimulation. Their performance here is compared with two separate cases: the same ...

1. The net fluxes of sodium and chloride from the lumen to the blood side of isolated sheep rumen epithelium were reduced by treatment of both sides of the epithelium with acetazolamide. 2. The changes in the net fluxes of sodium and chloride were significantly correlated and showed recovery after removal of acetazolamide. 3. The net flux of potassium from ...

... or 24-hour urine collection may be taken Test Preparation Needed? None The Test Sample What is being tested? Follicle-stimulating hormone ( ... a blood sample and throat culture. Is any test preparation needed to ensure the quality of the ...

ABSTRACT: INTRODUCTION: Acetazolamide is commonly used in chronic obstructive pulmonary disease (COPD) patients with metabolic alkalosis. Little is known of the pharmacodynamics of acetazolamide in the critically ill. We undertook a pharmacodynamic modeling of bicarbonate response to acetazolamide in COPD patients under mechanical ...

... Ranges Evidence-based Medicine Test Reliability Genetic Tests Forensic Tests Pharmacogenomics Collecting Samples Tests into Practice FDA ...

ICSH - blood test; Luteinizing hormone - blood test; Interstitial cell stimulating hormone - blood test ... called a pipette, or onto a slide or test strip. A bandage may be placed over the ...

We explored the action of luminal AVP in rabbit CCD perfused in vitro at 37 degrees C. Nanomolar concentrations of luminal AVP induced a sustained hyperpolarization of transepithelial voltage (Vt) in contrast to a transient hyperpolarization caused by basolateral AVP. 10 microM basolateral ouabain abolished the latter but not the former change in Vt. Despite a sustained hyperpolarization (from ...

We explored the action of luminal AVP in rabbit CCD perfused in vitro at 37 degrees C. Nanomolar concentrations of luminal AVP induced a sustained hyperpolarization of transepithelial voltage (Vt) in contrast to a transient hyperpolarization caused by basolateral AVP. 10 microM basolateral ouabain abolished the latter but not the former change in Vt. Despite a sustained hyperpolarization (from ...

Health Topics Drugs & Supplements Videos & Cool Tools ESPA�OL Secretin stimulation test Printer-friendly version Email this page to a friend Share The secretin stimulation...

Chitin is an essential structural component of the fungal cell wall. Chitinases are thought to be important for fungal cell wall remodelling, and inhibition of these enzymes has been proposed as a potential strategy for development of novel anti-fungals. The fungal pathogen Aspergillus fumigatus possesses two distinct multi-gene chitinase families. Here we explore ...

Cerebral blood flow (CBF) was measured by xenon-133 inhalation tomography in 18 patients with cerebrovascular disease before and 4 months after extracranial-intracranial bypass surgery. Only patients who showed a reduced CBF in areas that were intact on the CT scan and relevant to the clinical and angiographical findings were operated. The majority of the patients had suffered a minor stroke with ...

... test focuses on changes and responses in brain waves. The brain waves are stimulated by a clicking sound to evaluate ...

...2011-04-01 false Follicle-stimulating hormone test system. 862.1300 Section...862.1300 Follicle-stimulating hormone test system. (a) Identification. A follicle-stimulating hormone test system is a device intended...