Enterobacterial common antigen (ECA) is a polysaccharide found on the outer membrane of virtually all gram-negative enteric bacteria and consists of three sugars, N-acetyl-D-glucosamine, N-acetyl-D-mannosaminuronic acid, and 4-acetamido-4,6-dideoxy-D-galactose, organized into trisaccharide repeating units having the sequence ...
Energy Citations Database
... Acetyl Transferase regulate PGC-1α acetylation and its effects on glucose ... for the basic pathways of energy homeostasis, diabetes and metabolic ...
DTIC Science & Technology
... POLYMERIZATION, PROTEINS, MUTATIONS, GENES, RIBONUCLEIC ACIDS, ACETYLATION, HISTONES, TRANSFERASES, TRANSCRIPTION ...
... Keywords: Acetylation; Pro- opiomelanocortin; Dopamine. Descriptors : *BRAIN, *PEPTIDES, *ENZYME INHIBITORS, *TRANSFERASES ...
... Abstract : The activity changes of RNA polymerase, choline acetyl transferase, acetylcholinesterase and monoamine oxidase in five brain areas ...
... of acetylcarnitine from acetyl coenzyme A (CoA ... ACIDS, OXIDATION), (*MUSCLES, ENZYMES), TRANSFERASES, COENZYMES, DIPTERA, FLIGHT ...
Structural and biochemical analyses reveal how ornithine acetyl-transferases catalyse the reversible transfer of an acetyl-group from a basic (ornithine) to an acidic (glutamate) amino acid by employing a common mechanism involving an acetyl-enzyme intermediate but using different side chain binding modes. PMID:21796301
PubMed
The purpose of this proposal is to test the hypothesis that acetylation of PGC-1alpha by the Acetyl Transferase GCN5 associated proteins, Pc3 and WDR18, is a key regulatory modification that controls hepatic glucose production. This investigation has a de...
National Technical Information Service (NTIS)
... I .1--uei:=.. photolabeled fragments of carnitine acetyl- U transferase Dj "1-- _--i!. and several sirkgle samples from a L variety of itvestigators. k~~ T ...
... The other samples have been snake toxins, immunoglobulin fragments, photolabeled fragments of carnitine acetyl-transferase, and several single ...
... repressive chromatin structures through its intrinsic or associated histone acetyl transferase activity [27, 28]. The regulation of ... the cystine-rich C/H2 domain within the histone acetyl transferase a...
NBII National Biological Information Infrastructure
Heterologous expression of NodZ and NolL proteins in Rhizobium leguminosarum bv. viciae led to the production of acetyl fucosylated lipo-chitin oligosaccharides (LCOs), indicating that the NolL protein obtained from Mesorhizobium loti functions as an acetyl transferase. We show that the NolL-dependent acetylation ...
The biochemical basis underlying the genetic polymorphism of drug N-acetylation was investigated using a combination of in vivo and in vitro assays for arylamine N-acetyltransferase (NAT) activity and content in human liver. The acetylator phenotype of 26 surgical patients was determined using caffeine as an innocuous probe drug by measurement of the ...
PubMed Central
The effects of chronic 30-day electric field exposure on pineal serotonin N-acetyl transferase (EC 2.1.15) activity as well as melatonin and 5-methoxy tryptophol (5-MTOL) concentrations in rats, were assessed.
The hMOF protein is a chromatin-modifying factor. Chromatin structure plays a critical role in gene expression. Since hMOF has a chromodomain region as well as acetyl transferase activity, its inactivation can influence modification of chromatin during DN...
The hMOF protein is a chromatin-modifying factor. Chromatin structure plays a critical role in gene expression. Since hMOF has a chromodomain region as well as acetyl transferase activity its inactivation can influence modification of chromatin during DNA...
... D. Aventis CropScience PO Box 12014 2 T W. Alexander Drive Research ... gene encodes the phosphinothricin-N-acetyl transferase, which catalyzes the conversion of L ...
Center for Food Safety and Applied Nutrition (CFSAN)
The p53 tumor suppressor is a sequence-specific transcription factor that undergoes an abundance of post-translational modifications for its regulation and activation. Acetylation of p53 is an important reversible enzymatic process that occurs in response to DNA damage and genotoxic stress and is indispensible for p53 transcriptional activity. p53 was the first non-histone ...
The chromatin remodelling complex B-WICH, which comprises the William syndrome transcription factor (WSTF), SNF2h, and nuclear myosin 1 (NM1), is involved in regulating rDNA transcription, and SiRNA silencing of WSTF leads to a reduced level of 45S pre-rRNA. The mechanism behind the action of B-WICH is unclear. Here, we show that the B-WICH complex affects the chromatin structure and that ...
Sister chromatid cohesion is thought to involve entrapment of sister DNAs by a tripartite ring composed of the cohesin subunits Smc1, Smc3, and Scc1. Establishment of cohesion during S phase depends on acetylation of Smc3's nucleotide-binding domain (NBD) by the Eco1 acetyl transferase. It is destroyed at the onset of anaphase due to ...
Elongator is an evolutionary highly conserved complex. At least two of its cellular functions rely on the intrinsic lysine acetyl-transferase activity of the Elongator complex. Its two known substrates�Histone H3 and ?-Tubulin�reflect the different roles of Elongator in the cytosol and the nucleus. A picture seems to emerge in which nuclear Elongator could regulate the ...
Histone lysine acetylation is a key component of epigenetic regulation of gene transcription. Bromodomains, found in histone acetyl transferases and other chromatin-associated proteins, bind selectively to acetylated lysines, acting as "readers" of the histone code, and have recently been shown to contain a ...
