Antibody against acetylcholine receptor induces an increase in the rate of degradation of acetylcholine receptors on a mouse cell line (BC3H-1) and cultured rat skeletal muscle. The increased rate of degradation results in a lowered density of acetylcholine ...
NASA Astrophysics Data System (ADS)
The antagonism of hypothermia induced by Db-cGMP and acetylcholine + physostigmine by central administration of a cholinergic muscarine receptor antagonist ...
NASA Website
... Title : Turnover of Acetylcholine Receptors: Mechanisms of Regulation. ... Acetylcholine receptors, RA5 Neuromuscular junctions, Motor nerves. ...
DTIC Science & Technology
... This family includes Neu differentiation factor (NDF), heregulin (HRG), acetylcholine receptor inducing activity (ARIA), and the glial growth factors ...
Dihydroisohistrionicotoxin inhibits acetylcholine receptor-dependent 22Na+ uptake of cultured chick muscle cells with a KI of 0.2 micrometer. The inhibition is noncompetitive with respect to agonists. The toxin enhances desensitization of the receptor by agonists which is accompanied by a 10-fold increase in ...
PubMed Central
... Title : Primary Structure of Nicotinic Acetylcholine Receptor. ... One of the neurotransmitters used in the mammalian brain is acetylcholine. ...
Purified ? -toxin from Naja nigricollis snake venom labeled by [3H]acetylation binds specifically to the acetylcholine receptors of mouse neuroblastoma cells. Toxin binding was inhibited by inhibitors for nicotinic and muscarinic acetylcholine receptors. Clones of neuroblastoma cells were selected for low ...
... Accession Number : ADD754483. Title : ACETYLCHOLINE RECEPTOR CHANNEL IMAGED IN THE OPEN STATE. Descriptive ...
... Title : ACETYLCHOLINE RECEPTOR BINDING CHARACTERISTICS OF SNAKE AND CONE SNAIL VENOM POSTSYNAPTIC NEUROTOXINS ...
Black lipid membranes were formed with oxidized cholesterol in the presence of either the acetylcholine receptor, purified from the electric organ of the electric ray Torpedo californica or its tryptic digest. In both cases, conductance of cations increased and was dependent on the concentration of the receptor protein. Conductance of ...
Energy Citations Database
We investigated the interaction between ambient histamine and acetylcholine by studying ? oscillations in rat hippocampus, induced by bath application of acetylcholine (10 �M combined with 2 �M physostigmine). The power of ? was significantly increased by the H1 antagonist, fexofenadine, and H2 receptor ...
PubMed
Partial contents include: Light-activated channels in limulus ventral photoreceptors; Paramagnetic hydrophobic ions as probes for electrically active conformational transitions in Ion channels; Acetylcholine receptor. Dynamic properties; Acetylcholine-activated channel current-voltage relations in symmetrical Na(+) solutions; A ...
Mar 1, 2011... induces the aggregation of nicotinic acetylcholine receptors on ... aggregation activity with as little as 5 ug secreted protein per ml ...
... W. and Berman, JD (1989) Mechanism of agonist-induced down-regulation and subsequent recovery of muscarinic acetylcholin receptors in a ...
... A. Davenport, R. M. Weiss, and J. Latifpour. Diabetes-induced alterations in the properties of muscarinic cholinergic ... ...
NBII National Biological Information Infrastructure
1. Histamine secretion from rat mast cells occurs in the presence of nanomolar concentrations of acetylcholine. 2. Intact glycolytic and oxidative metabolism is required for the acetylcholine-induced histamine secretion. Removal of extracellular glucose, hypoxia, cyanide and monoiodoacetate almost completely inhibit the secretion. 3. The secretion of ...
This study evaluates the biochemical and genetic aspects of the acetylcholine receptor proteins and cholinergic ligands in Drosophila melanogaster and Torpedo californica. Included are (1) a comparative study of nicotinic ligand-induced cation release from acetylcholine receptors isolated from ...
Nicotinic acetylcholine receptors are ligand-gated ion conducting transmembrane channels from the Cys-loop receptor super-family. The ?4?2 subtype is the predominant heteromeric subtype of nicotinic receptors found in the brain. Allosteric modulators for ?4?2 receptors interact at a site other ...
Fourier transform infrared spectroscopy is used to characterize specific interactions between negatively charged lipids, such as phosphatidic acid, and the purified nicotinic acetylcholine receptor from Torpedo californica. The specific interaction of phosphatidic acid with acetylcholine receptor is demonstrated by ...
A genomic clone encoding the gene for the mouse M1 muscarinic acetylcholine receptor has been isolated, placed under the control of the zinc-inducible mouse metallothionein promoter, and transfected into mouse Y1 adrenal cells. The receptor concentration ...
National Technical Information Service (NTIS)
... Title : Activation, Inactivation, and Desensitization of Acetylcholine Receptor Channel Complex Detected by Binding of Perhydrohistrionicotoxin. ...
The reactivity of isolated porcine coronary venous segments to acetylcholine, noradrenaline, and histamine was tested in organ bath experiments. Acetylcholine dilated precontracted venous preparations endothelium-dependently. This relaxation was inhibited by atropine indicating the muscarinic nature of this response. Noradrenaline contracted the vessels by ...
Effects of the neurotransmitter acetylcholine are divided into muscarinic or nicotinic depending on the receptors that are activated. Stimulation of muscarinic receptors results in vasodilation, decreased heart rate and cardiac contractility, increased se...
