... Density, Morphological Remodeling, and Butyrylcholinesterase Activity Can Sustain Muscle Function in Acetylcholinesterase Knockout Mice. ...
DTIC Science & Technology
... knockout mice; muscle tension Correspondence to: M. Adler; e-mail: Michael.Adler@amedd ... matched littermates and exhibited an unsteady gait, ...
Nicotinic acetylcholine receptors are pentameric ligand-gated ion channels, which are involved in a wide range of neuronal functions. During the past decade, a large number of nicotinic acetylcholine receptor subunits have been cloned and showed a discreet yet overlapping distribution pattern. Recently, several ...
E-print Network
by the American College of Cardiology The parasympathetic nervous system acts through the vagus nerve to regulate stimulation leads to a release of acetylcholine from the vagus nerve. Acetylcholine binds muscarinic receptors). DISCUSSION Acetylcholine is released from the vagus nerve of the parasympathetic system ...
... Title : Turnover of Acetylcholine Receptors: Mechanisms of Regulation. ... Acetylcholine receptors, RA5 Neuromuscular junctions, Motor nerves. ...
... Title : Primary Structure of Nicotinic Acetylcholine Receptor. ... One of the neurotransmitters used in the mammalian brain is acetylcholine. ...
Nerve-evoked contractions were studied in vitro in phrenic nerve- hemidiaphragm preparations from strain 129X1 acetyloholinesterase knockout (AChE-/-) mice and their wild-type littermates (AChE+/+). The AChE-/- mice fail to express AChE but have normal le...
National Technical Information Service (NTIS)
... Accession Number : ADD754483. Title : ACETYLCHOLINE RECEPTOR CHANNEL IMAGED IN THE OPEN STATE. Descriptive ...
... Title : ACETYLCHOLINE RECEPTOR BINDING CHARACTERISTICS OF SNAKE AND CONE SNAIL VENOM POSTSYNAPTIC NEUROTOXINS ...
Nicotinic acetylcholine receptors play important roles in numerous cognitive processes as well as in several debilitating central nervous system (CNS) disorders. In order to fully elucidate the diverse roles of nicotinic acetylcholine receptors in CNS function and dysfunction, a detailed knowledge of their cellular ...
PubMed
... Title : Activation, Inactivation, and Desensitization of Acetylcholine Receptor Channel Complex Detected by Binding of Perhydrohistrionicotoxin. ...
Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1)�the neuronal ?-secretase responsible for producing ?-amyloid (A?) peptides�emerged as one of the key therapeutic targets of Alzheimer's disease (AD). Although complete ablation of the BACE1 gene prevents A? formation, we reported that BACE1 knockout mice display severe presynaptic deficits at mossy fiber (MF) to ...
PubMed Central
