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1
Turnover of Acetylcholine Receptors: Mechanisms of ...
1990-12-31

... Title : Turnover of Acetylcholine Receptors: Mechanisms of Regulation. ... Acetylcholine receptors, RA5 Neuromuscular junctions, Motor nerves. ...

DTIC Science & Technology

2
Potentials of Mean Force for Acetylcholine Unbinding from the Alpha7 Nicotinic Acetylcholine Receptor Ligand Binding Domain
2006-03-08

The nicotinic acetylcholine receptor is a prototype ligand-gated ion channel that mediates signal transduction in the neuromuscular junctions and other cholinergic synapses. The molecular basis for the energetics of ligand binding and unbinding is critical to our understanding of the pharmacology of this class of ...

PubMed Central

3
Acetylcholine-Synthesizing T Cells Relay Neural Signals in a Vagus Nerve Circuit.
2011-09-15

Neural circuits regulate cytokine production to prevent potentially damaging inflammation. A prototypical vagus nerve circuit, the inflammatory reflex, inhibits tumor necrosis factor-? production in spleen by a mechanism requiring acetylcholine signaling through the alpha 7 nicotinic acetylcholine receptor ...

PubMed

4
Primary Structure of Nicotinic Acetylcholine Receptor.
1992-05-06

... Title : Primary Structure of Nicotinic Acetylcholine Receptor. ... One of the neurotransmitters used in the mammalian brain is acetylcholine. ...

DTIC Science & Technology

5
ACETYLCHOLINE RECEPTOR CHANNEL IMAGED IN THE ...
1995-01-05

... Accession Number : ADD754483. Title : ACETYLCHOLINE RECEPTOR CHANNEL IMAGED IN THE OPEN STATE. Descriptive ...

DTIC Science & Technology

6
ACETYLCHOLINE RECEPTOR BINDING ...
1992-12-17

... Title : ACETYLCHOLINE RECEPTOR BINDING CHARACTERISTICS OF SNAKE AND CONE SNAIL VENOM POSTSYNAPTIC NEUROTOXINS ...

DTIC Science & Technology

7
Synthesis, Trafficking, and Localization of Muscarinic Acetylcholine Receptors
2008-05-16

Muscarinic acetylcholine receptors are members of the G-protein coupled receptor superfamily that are expressed in and regulate the function of neurons, cardiac and smooth muscle, glands, and many other cell types and tissues. The correct trafficking of membrane proteins to the cell surface and their subsequent localization at ...

PubMed Central

8
Cholinergic modulation of response properties and orientation tuning of neurons in primary visual cortex of anaesthetized Marmoset monkeys
2006-07-01

Cortical processing is strongly influenced by the actions of neuromodulators such as acetylcholine (ACh). Early studies in anaesthetized cats argued that acetylcholine can cause a sharpening of orientation tuning functions and an improvement of the signal-to-noise ratio (SNR) of neuronal responses in primary visual cortex (V1). Recent ...

PubMed Central

9
Primary Structure of Nicotinic Acetylcholine Receptor.
1992-01-01

Signals are transmitted between cells in the brain using neurotransmitters and neurotransmitter receptors. Poisons that interfere with this process stop normal brain function and often kill nerve cells. One of the neurotransmitters used in the mammalian b...

National Technical Information Service (NTIS)

10
Activation, Inactivation, and Desensitization of Acetylcholine ...
1980-01-16

... Title : Activation, Inactivation, and Desensitization of Acetylcholine Receptor Channel Complex Detected by Binding of Perhydrohistrionicotoxin. ...

DTIC Science & Technology

11
Cellular/Molecular A Conserved Postsynaptic Transmembrane Protein Affecting

and levamisole, that are used to dissect neuromuscular signaling in C. elegans (Brenner, 1974; Hosono and Kamiya to the acetylcholine receptor agonist levamisole will persist if the defect is on the presynaptic site; however, if postsynaptic signaling components are dysfunctional, animals will be resistant to the ...

E-print Network

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