The effects of intracellular application of three compounds - QX314, N-ethylguanidine and N-octylguanidine - on the acetylcholine-activated ionic channels in chick myoballs were examined. Voltage-clamped myoballs were internally perfused using the suction-pipette technique. Changes in the internal ionic environment of myoballs were demonstrated by: (1) alteration of the reversal potential for both ...
PubMed Central
The systemic vasculature exhibits attenuated vasoconstriction following hypobaric chronic hypoxia (CH) that is associated with endothelium-dependent vascular smooth muscle (VSM) cell hyperpolarization. We hypothesized that increased activity of endothelial cell (EC) large-conductance, calcium-activated potassium (BK(Ca)) channels contributes to this response. Gracilis ...
PubMed
... Descriptors : *POTASSIUM COMPOUNDS, ALTERNATING CURRENT, BROMIDES, CRYSTALS, ELECTRICAL PROPERTIES, SPACE CHARGE. ...
DTIC Science & Technology
... The Select Committee has found no data suggesting that the use of sodium or potassium hydroxides, as currently practiced in food processing, is hazardous to ...
Center for Food Safety and Applied Nutrition (CFSAN)
1. The mechanism of the sustained acetylcholine-induced endothelium-dependent hyperpolarization (EDH) in intact rat small mesenteric arteries prestimulated with noradrenaline (10(-6) M) was investigated by means of the single microelectrode voltage-clamp method. 2. The vascular smooth muscle cells (VSMCs) in this preparation are poorly or even not coupled for the reasons that: ...
Vol. 31 (2000) ACTA PHYSICA POLONICA B No 5 COMPARISON OF SINGLE CHANNEL POTASSIUM CURRENT recordings of potassium current through a big conductance locust potassium chan- nel (BK-channel) and a track- sion analysis. A similar dependence of potassium ...
E-print Network
1. Evoked ganglionic action potentials and drug-induced changes in resting potential were recorded by the sucrose-gap method. The height of the action potential was 10-20 mV. 2. Since the amplitude of the P wave is inversely proportional to the external potassium concentration between 0�5 and 12 mM, the P wave is probably caused by a phase of increased permeability to ...
1. The release of catecholamines (CA) from rat adrenal incubated in vivo in Locke solution was studied. 2. Acetylcholine-induced release of CA and CA release by 56 mM KCl were inhibited by verapamil and lanthanum chloride which block calcium permeability. 3. CA secretion induced by salbutamol or by theophylline was unaffected by either verapamil or lanthanum chloride. 4. ...
... Descriptors : *NERVE CELLS, *CHEMORECEPTORS, SODIUM, CHLORIDES, DOPAMINE, POTASSIUM, IONIC CURRENT ...
Partial contents include: Light-activated channels in limulus ventral photoreceptors; Paramagnetic hydrophobic ions as probes for electrically active conformational transitions in Ion channels; Acetylcholine receptor. Dynamic properties; Acetylcholine-activated channel current-voltage relations in symmetrical Na(+) solutions; A molecular model for an acetylcholine binding ...
Energy Citations Database
Electrophysiological, biochemical, and Ca2+ imaging studies of cultured mouse myotubes were used to investigate whether the neurotransmitter acetylcholine causes an increase in intracellular Ca2+ concentration ([Ca2+]i) through activation of a second messenger system. Bath applications of acetylcholine to myotubes (i) elicited a significant membrane current even in a ...
399 Potassium Currents in Developing Neurons ANGELES B. RIBERAa Department of Physiology, Colorado 80262, USA ABSTRACT: In Xenopus spinal neurons, delayed rectifier type voltage-dependent potassium suggested that the diverse population of neurons expressed a common potassium channel. Thus, recent efforts
Production of potassium nitrate, a fertilizer currently purchased by KSC for use ... Installation at the HMF for testing under actual operating conditions. ...
NASA Website
The influence of an external field on an ion current pattern in biological and synthetic systems was investigated. The patch clamp recordings of potassium current through a big conductance locust potassium channel (BK-channel) and a track-etched polyethylene terephthalate membrane were examined by the power ...
NASA Astrophysics Data System (ADS)
... COMPARTMENTS, METABOLISM, PLATINUM, CYANIDES, ELECTRIC CURRENT, PLEXIGLAS, METHYLENE BLUE, GLUCOSE, POTASSIUM ...
Kv7.1 (KCNQ1) channels are regulators of several physiological processes including vasodilatation, repolarization of cardiomyocytes, and control of secretory processes. A number of Kv7.1 pore mutants are sensitive to extracellular potassium. We hypothesized that extracellular potassium also modulates wild-type Kv7.1 channels. The Kv7.1 ...
