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1
The Rtt109 histone acetyltransferase facilitates error-free replication to prevent CAG/CTG repeat contractions.
2010-01-18

Lysine 56 is acetylated on newly synthesized histone H3 in yeast, Drosophila and mammalian cells. All of the proteins involved in histone H3 lysine 56 (H3K56) acetylation are important for maintaining genome integrity. These include Rtt109, a histone acetyltransferase, responsible for acetylating H3K56, Asf1, a histone H3/H4 chaperone, and Hst3 and Hst4, histone deacetylases ...

PubMed

2
The Rtt109 histone acetyltransferase facilitates error-free replication to prevent CAG/CTG repeat contractions
2010-01-18

Lysine 56 is acetylated on newly synthesized histone H3 in yeast, Drosophila and mammalian cells. All of the proteins involved in histone H3 lysine 56 (H3K56) acetylation are important for maintaining genome integrity. These include Rtt109, a histone acetyltransferase, responsible for acetylating H3K56, Asf1, a histone H3/H4 chaperone, and Hst3 and Hst4, histone deacetylases ...

PubMed Central

3
Software Guide Error-Free Assembly.
1998-03-24

... Accession Number : ADD815180. Title : Software Guide Error-Free Assembly. Descriptive Note : Journal article,. Corporate Author : ...

DTIC Science & Technology

4
Fast Error-Free Algorithms for Polynomial Matrix ...
2011-05-13

... 4. TITLE AND SUBTITLE Fast Error-Free Algorithms for Polynomial Matrix Computations 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. ...

DTIC Science & Technology

5
Error Free Software - NASA

Mar 2, 2011 ... They designed software which is logically error-free, which, in one instance, was found to increase productivity by 600%. USE. ...

NASA Website

6
Role of yeast Rad5 and its human orthologs, HLTF and SHPRH in DNA damage tolerance.
2010-01-21

In the yeast Saccharomyces cerevisiae, the Rad6-Rad18 DNA damage tolerance pathway constitutes a major defense system against replication fork blocking DNA lesions. The Rad6-Rad18 ubiquitin-conjugating/ligase complex governs error-free and error-prone translesion synthesis by specialized DNA polymerases, as well as an error-free Rad5-dependent postreplicative repair pathway. ...

PubMed

7
Novel bacterial N-acetyltransferase gene for herbicide detoxification in land plants and selection maker in plant transformation.
2009-05-07

Phosphinothricin (PPT) is the active ingredient in bialaphos, which specifically inhibits glutamine synthetase in land plants. We isolated a novel PPT-resistant gene from a soil bacterium, Nocardia sp., and characterized it. The encoded protein, consisting of 177 amino acids, showed significant similarity to bacterial N-acetyltransferases, and we originally designated the gene ...

PubMed

8
Ringlike structure of the Deinococcus radiodurans genome: a key to radioresistance?
2003-01-10

The bacterium Deinococcus radiodurans survives ionizing irradiation and other DNA-damaging assaults at doses that are lethal to all other organisms. How D. radiodurans accurately reconstructs its genome from hundreds of radiation-generated fragments in the absence of an intact template is unknown. Here we show that the D. radiodurans genome assumes an unusual toroidal morphology that may ...

PubMed

9
Multifarious system for quantitative analysis of histologic compartments.
1997-04-01

A system is presented for measuring relative volumes of histologic compartments in microscopic slides. The computer program for that system was written by us as an MS windows 3.x application. The applied method of measurements, based on the "point-counting" technique, requires the recognition of the compartments, corresponding to the selected points of an image. The neural network was employed to ...

PubMed

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