Good glycaemic control continues to be the most effective therapeutic manoeuvre to reduce the risk of development and/or progression of microvascular disease, and therefore remains the cornerstone of diabetes management despite recent scepticism about tight glucose control strategies. The impact on macrovascular complications is still ...

Recommendations for the management of type 2 diabetes include rigorous control of blood glucose levels and other risk factors, such as hypertension and dyslipidaemia. In clinical practice, many patients do not reach goals for glycaemic control. Causes of failure to control blood glucose include progression of ...

IntroductionA single centre has reported that implementation of an intensive insulin protocol, aiming for tight glycaemic control (blood glucose 4.4 to 6.1 mmol/l), resulted in significant reduction in mortality in longer stay medical and surgical critically ill patients. Our aim was to determine the degree to which tight glycaemic ...

Aims/hypothesisAfter achieving glycaemic control, many type 2 diabetic patients relapse to clinically significant levels of hyperglycaemia. We sought to determine the optimal frequency of telephone contact by nurse practitioners that was necessary to prevent glycaemic relapse.MethodsThis parallel, randomised ...

Aim: The purpose of this study was to evaluate if superior glycaemic control could be achieved with Avandamet� (rosiglitazone/metformin/AVM) compared with metformin (MET) monotherapy, and if glycaemic effects attained with AVM are durable over 18 months of treatment. Bone mineral density (BMD) and bone biomarkers ...

To investigate the quality of glycaemic control that is achievable in diabetic patients with persistent proteinuria and asymptomatic but declining renal function three matched groups of patients were studied. The first comprised diabetics with proteinuria receiving continuous subcutaneous insulin infusion; the second, diabetics without ...

Nosocomial Infection; Interleukines; Glycemic Control; Cardiac Surgery With Cardiopulmonary Bypass Circuit

Diabetes Mellitus is a chronic, lifelong metabolic disorder characterized by an elevated blood glucose level resulting from an absolute or relative shortage of insulin. Self-monitoring of blood glucose (SMBG) has escalated over the years following the outcomes of evidence demonstrating a strong correlation between tight blood glucose control and the significant reduction of ...