Sample records for acquired motor fusion

  1. Reliability of the Motor Learning Strategy Rating Instrument for Children and Youth with Acquired Brain Injury

    ERIC Educational Resources Information Center

    Kamath, Trishna; Pfeifer, Megan; Banerjee-Guenette, Priyanka; Hunter, Theresa; Ito, Julia; Salbach, Nancy M.; Wright, Virginia; Levac, Danielle

    2012-01-01

    Purpose: To evaluate reliability and feasibility of the Motor Learning Strategy Rating Instrument (MLSRI) in children with acquired brain injury (ABI). The MLSRI quantifies the extent to which motor learning strategies (MLS) are used within physiotherapy (PT) interventions. Methods: PT sessions conducted by ABI team physiotherapists with a…

  2. Human bone marrow-derived stem cells acquire epithelial characteristics through fusion with gastrointestinal epithelial cells.

    PubMed

    Ferrand, Jonathan; Noël, Danièle; Lehours, Philippe; Prochazkova-Carlotti, Martina; Chambonnier, Lucie; Ménard, Armelle; Mégraud, Francis; Varon, Christine

    2011-01-01

    Bone marrow-derived mesenchymal stem cells (MSC) have the ability to differentiate into a variety of cell types and are a potential source for epithelial tissue repair. Several studies have demonstrated their ability to repopulate the gastrointestinal tract (GIT) in bone marrow transplanted patients or in animal models of gastrointestinal carcinogenesis where they were the source of epithelial cancers. However, mechanism of MSC epithelial differentiation still remains unclear and controversial with trans-differentiation or fusion events being evoked. This study aimed to investigate the ability of MSC to acquire epithelial characteristics in the particular context of the gastrointestinal epithelium and to evaluate the role of cell fusion in this process. In vitro coculture experiments were performed with three gastrointestinal epithelial cell lines and MSC originating from two patients. After an 8 day coculture, MSC expressed epithelial markers. Use of a semi-permeable insert did not reproduce this effect, suggesting importance of cell contacts. Tagged cells coculture or FISH on gender-mismatched cells revealed clearly that epithelial differentiation resulted from cellular fusion events, while expression of mesenchymal markers on fused cells decreased over time. In vivo cell xenograft in immunodeficient mice confirmed fusion of MSC with gastrointestinal epithelial cells and self-renewal abilities of these fused cells. In conclusion, our results indicate that fusion could be the predominant mechanism by which human MSC may acquire epithelial characteristics when in close contact with epithelial cells from gastrointestinal origin . These results could contribute to a better understanding of the cellular and molecular mechanisms allowing MSC engraftment into the GIT epithelium. PMID:21573181

  3. A Hybrid Classifier Fusion Approach for Motor Unit Potential Classification During EMG Signal Decomposition

    Microsoft Academic Search

    Sarbast Rasheed; Daniel W. Stashuk; Mohamed S. Kamel

    2007-01-01

    In this paper, we propose a hybrid classifier fusion scheme for motor unit potential classification during electromyographic (EMG) signal decomposition. The scheme uses an aggregator module consisting of two stages of classifier fusion: the first at the abstract level using class labels and the second at the measurement level using confidence values. Performance of the developed system was evaluated using

  4. Remote sensing of shorelines using data fusion of hyperspectral and multispectral imagery acquired from mobile and fixed platforms

    NASA Astrophysics Data System (ADS)

    Bostater, Charles R.; Frystacky, Heather

    2012-06-01

    An optimized data fusion methodology is presented and makes use of airborne and vessel mounted hyperspectral and multispectral imagery acquired at littoral zones in Florida and the northern Gulf of Mexico. The results demonstrate the use of hyperspectral-multispectral data fusion anomaly detection along shorelines and in surface and subsurface waters. Hyperspectral imagery utilized in the data fusion analysis was collected using a 64-1024 channel, 1376 pixel swath width; temperature stabilized sensing system; an integrated inertial motion unit; and differential GPS. The imaging system is calibrated using dual 18 inch calibration spheres, spectral line sources, and custom line targets. Simultaneously collected multispectral three band imagery used in the data fusion analysis was derived either a 12 inch focal length large format camera using 9 inch high speed AGFA color negative film, a 12.3 megapixel digital camera or dual high speed full definition video cameras. Pushbroom sensor imagery is corrected using Kalman filtering and smoothing in order to correct images for airborne platform motions or motions of a small vessel. Custom software developed for the hyperspectral system and the optimized data fusion process allows for post processing using atmospherically corrected and georeferenced reflectance imagery. The optimized data fusion approach allows for detecting spectral anomalies in the resolution enhanced data cubes. Spectral-spatial anomaly detection is demonstrated using simulated embedded targets in actual imagery. The approach allows one to utilize spectral signature anomalies to identify features and targets that would otherwise not be possible. The optimized data fusion techniques and software has been developed in order to perform sensitivity analysis of the synthetic images in order to optimize the singular value decomposition model building process and the 2-D Butterworth cutoff frequency selection process, using the concept of user defined "feature areas". The data fusion "synthetic imagery" forms a basis for spectral-spatial resolution enhancement for optimal band selection and remote sensing algorithm development within "spectral anomaly areas". The methods are applied to imagery intended to support Deepwater Horizon oil spill remediation and recovery efforts. Sensitivity analysis demonstrates the data fusion methodology is most sensitive to (a) the pixels and features used in the SVD model building process and (b) the 2-D Butterworth cutoff frequency optimized by application of K-S nonparametric test. The optimized image fusion approach is transferable to sensor data acquired from other platforms, including autonomous underwater vehicles using near real time processing.

  5. Transplantation of Xenopus laevis Tissues to Determine the Ability of Motor Neurons to Acquire a Novel Target

    PubMed Central

    Elliott, Karen L.; Houston, Douglas W.; Fritzsch, Bernd

    2013-01-01

    The evolutionary origin of novelties is a central problem in biology. At a cellular level this requires, for example, molecularly resolving how brainstem motor neurons change their innervation target from muscle fibers (branchial motor neurons) to neural crest-derived ganglia (visceral motor neurons) or ear-derived hair cells (inner ear and lateral line efferent neurons). Transplantation of various tissues into the path of motor neuron axons could determine the ability of any motor neuron to innervate a novel target. Several tissues that receive direct, indirect, or no motor innervation were transplanted into the path of different motor neuron populations in Xenopus laevis embryos. Ears, somites, hearts, and lungs were transplanted to the orbit, replacing the eye. Jaw and eye muscle were transplanted to the trunk, replacing a somite. Applications of lipophilic dyes and immunohistochemistry to reveal motor neuron axon terminals were used. The ear, but not somite-derived muscle, heart, or liver, received motor neuron axons via the oculomotor or trochlear nerves. Somite-derived muscle tissue was innervated, likely by the hypoglossal nerve, when replacing the ear. In contrast to our previous report on ear innervation by spinal motor neurons, none of the tissues (eye or jaw muscle) was innervated when transplanted to the trunk. Taken together, these results suggest that there is some plasticity inherent to motor innervation, but not every motor neuron can become an efferent to any target that normally receives motor input. The only tissue among our samples that can be innervated by all motor neurons tested is the ear. We suggest some possible, testable molecular suggestions for this apparent uniqueness. PMID:23383335

  6. Mechanical Sensorless Control of IPM Motor Using PWM Harmonics Information Acquired from DC-Bus Current Kazunori Murata*

    E-print Network

    Fujimoto, Hiroshi

    PWM IPM * Mechanical Sensorless Control of IPM Motor Using PWM Harmonics Information, which prove feasibility of the proposed technique. IPM PWM KeywordsIPM motor, frequency-modulated three-phase carrier, DC-bus current, switching pattern, PWM harmonics IPM [1] PWM PWM [2] CT PWM

  7. Acquired inflammatory demyelinating neuropathies.

    PubMed

    Ensrud, E R; Krivickas, L S

    2001-05-01

    The acquired demyelinating neuropathies can be divided into those with an acute onset and course and those with a more chronic course. The acute neuropathies present as Guillain-Barré syndrome and include acute inflammatory demyelinating polyradiculoneuropathy (AIDP), Miller Fisher syndrome, acute motor axonal neuropathy (AMAN), acute motor and sensory axonal neuropathy (AMSAN), and acute pandysautonomia. The chronic neuropathies are collectively known as chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and include MADSAM (multifocal acquired demyelinating sensory and motor neuropathy, also know as Lewis-Sumner syndrome) and DADS (distal acquired demyelinating symmetric neuropathy) as variants. The clinical features, pathology, pathogenesis, diagnosis, treatment, rehabilitation, and prognosis of these neuropathies are discussed. PMID:11345010

  8. [Disruption of acquired head and paw movement coordination after unilateral lesioning of the motor cortex in dogs (a kinematic analysis)].

    PubMed

    Pavlova, O G; Mats, V N

    2001-01-01

    Dogs were trained to remove a cup with meat to the head bent down to the feeder and hold the limb flexed during eating. At the early stage of learning, the stable innate head-forelimb coordination characteristic for untrained animals was manifest. The forelimb flexion was accompanied by anticipatory lifting of the bent head, and the following bending of the head led to an extension of the flexed forelimb. The opposite coordination, i.e., the lifting and holding of the forelimb when the head is bent down, was achieved only by training. The lesion of the motor cortex contralateral to the working forelimb in the trained dogs led to a prolonged disturbance of the simultaneous holding of the flexed forelimb and the head bent down. The lesion of the motor cortex did not affect the individual movements but disturbed their coordination. In the operated dogs the innate relationships between the head and forelimb movement recovered. The results support the previous finding that the lesion of the motor cortex led to recovery of the innate coordination transformed in the process of learning. PMID:11871029

  9. Fusion

    Microsoft Academic Search

    Robin Herman

    1990-01-01

    The book abounds with fascinating anecdotes about fusion's rocky path: the spurious claim by Argentine dictator Juan Peron in 1951 that his country had built a working fusion reactor, the rush by the United States to drop secrecy and publicize its fusion work as a propaganda offensive after the Russian success with Sputnik; the fortune Penthouse magazine publisher Bob Guccione

  10. Acquired amegakaryocytic thrombocytopenia associated with proliferation of gamma/delta TCR T-lymphocytes and a BCR-ABL (p210) fusion transcript.

    PubMed

    Colovic, Milica; Pavlovic, Sonja; Kraguljac, Nada; Colovic, Natasa; Jankovic, Gradimir; Sefer, Dijana; Tosic, Natasa

    2004-11-01

    Acquired amegakaryocytic thrombocytopenia (AATP) in adults is a rare disorder characterized by severe thrombocytopenia and decreased or absent megakaryocytes in an otherwise normal bone marrow. We present a 44-yr-old man in whom the diagnosis of AATP was established in January 2001. Immunophenotyping of the peripheral blood lymphocytes showed a relative increase in the subpopulation of gamma/delta T-cell receptor (TCR) positive (gamma/delta TCR(+)) and (CD4, CD8) negative T lymphocytes, and PCR suggested a monoclonal pattern of TCR gamma chain gene rearrangement. Cytogenetic examination of his bone marrow cells showed a normal male karyotype but RT-PCR analysis revealed a BCR-ABL (p210) fusion transcript. The inhibition of CFU-Mk growth mediated by the patient's T lymphocytes indicated that the pathogenic mechanism for AATP could be an immunological attack on megakaryocyte progenitors where the gamma/delta TCR-positive T lymphocytes are directly involved. The case emphasizes the complex association of T-lymphocyte monoclonal proliferation and AATP. PMID:15458517

  11. Acquired Brain Injury Program.

    ERIC Educational Resources Information Center

    Schwartz, Stacey Hunter

    This paper reviews the Acquired Brain Injury (ABI) Program at Coastline Community College (California). The ABI Program is a two-year, for-credit educational curriculum designed to provide structured cognitive retraining for adults who have sustained an ABI due to traumatic (such as motor vehicle accident or fall) or non-traumatic(such as…

  12. Fusion

    NASA Astrophysics Data System (ADS)

    Herman, Robin

    1990-10-01

    The book abounds with fascinating anecdotes about fusion's rocky path: the spurious claim by Argentine dictator Juan Peron in 1951 that his country had built a working fusion reactor, the rush by the United States to drop secrecy and publicize its fusion work as a propaganda offensive after the Russian success with Sputnik; the fortune Penthouse magazine publisher Bob Guccione sank into an unconventional fusion device, the skepticism that met an assertion by two University of Utah chemists in 1989 that they had created "cold fusion" in a bottle. Aimed at a general audience, the book describes the scientific basis of controlled fusion--the fusing of atomic nuclei, under conditions hotter than the sun, to release energy. Using personal recollections of scientists involved, it traces the history of this little-known international race that began during the Cold War in secret laboratories in the United States, Great Britain and the Soviet Union, and evolved into an astonishingly open collaboration between East and West.

  13. Pancreatic Ductal Cells Acquire Mesenchymal Characteristics through Cell Fusion with Bone Marrow-Derived Mesenchymal Stem Cells and SIRT1 Attenuates the Apoptosis of Hybrid Cells

    Microsoft Academic Search

    Shanmiao Gou; Tao Liu; Xiangsheng Li; Jing Cui; Chidan Wan; Chunyou Wang

    2012-01-01

    Bone marrow-derived mesenchymal stem cells (bMSCs) contribute to tissue repair and regeneration. Cell fusion between somatic cells and bMSCs to form hybrid cells may have an important role in tissue repair through the subsequent reprogramming of the somatic cell nucleus. Few studies have assessed the mesenchymal characteristics of fusion-induced hybrid cells and their survival mechanisms. In this study, we investigated

  14. A faster, high resolution, mtPA-GFP-based mitochondrial fusion assay acquiring kinetic data of multiple cells in parallel using confocal microscopy.

    PubMed

    Lovy, Alenka; Molina, Anthony J A; Cerqueira, Fernanda M; Trudeau, Kyle; Shirihai, Orian S

    2012-01-01

    Mitochondrial fusion plays an essential role in mitochondrial calcium homeostasis, bioenergetics, autophagy and quality control. Fusion is quantified in living cells by photo-conversion of matrix targeted photoactivatable GFP (mtPAGFP) in a subset of mitochondria. The rate at which the photoconverted molecules equilibrate across the entire mitochondrial population is used as a measure of fusion activity. Thus far measurements were performed using a single cell time lapse approach, quantifying the equilibration in one cell over an hour. Here, we scale up and automate a previously published live cell method based on using mtPAGFP and a low concentration of TMRE (15 nm). This method involves photoactivating a small portion of the mitochondrial network, collecting highly resolved stacks of confocal sections every 15 min for 1 hour, and quantifying the change in signal intensity. Depending on several factors such as ease of finding PAGFP expressing cells, and the signal of the photoactivated regions, it is possible to collect around 10 cells within the 15 min intervals. This provides a significant improvement in the time efficiency of this assay while maintaining the highly resolved subcellular quantification as well as the kinetic parameters necessary to capture the detail of mitochondrial behavior in its native cytoarchitectural environment. Mitochondrial dynamics play a role in many cellular processes including respiration, calcium regulation, and apoptosis. The structure of the mitochondrial network affects the function of mitochondria, and the way they interact with the rest of the cell. Undergoing constant division and fusion, mitochondrial networks attain various shapes ranging from highly fused networks, to being more fragmented. Interestingly, Alzheimer's disease, Parkinson's disease, Charcot Marie Tooth 2A, and dominant optic atrophy have been correlated with altered mitochondrial morphology, namely fragmented networks. Often times, upon fragmentation, mitochondria become depolarized, and upon accumulation this leads to impaired cell function. Mitochondrial fission has been shown to signal a cell to progress toward apoptosis. It can also provide a mechanism by which to separate depolarized and inactive mitochondria to keep the bulk of the network robust. Fusion of mitochondria, on the other hand, leads to sharing of matrix proteins, solutes, mtDNA and the electrochemical gradient, and also seems to prevent progression to apoptosis. How fission and fusion of mitochondria affects cell homeostasis and ultimately the functioning of the organism needs further understanding, and therefore the continuous development and optimization of how to gather information on these phenomena is necessary. Existing mitochondrial fusion assays have revealed various insights into mitochondrial physiology, each having its own advantages. The hybrid PEG fusion assay, mixes two populations of differently labeled cells (mtRFP and mtYFP), and analyzes the amount of mixing and colocalization of fluorophores in fused, multinucleated, cells. Although this method has yielded valuable information, not all cell types can fuse, and the conditions under which fusion is stimulated involves the use of toxic drugs that likely affect the normal fusion process. More recently, a cell free technique has been devised, using isolated mitochondria to observe fusion events based on a luciferase assay. Two human cell lines are targeted with either the amino or a carboxy terminal part of Renilla luciferase along with a leucine zipper to ensure dimerization upon mixing. Mitochondria are isolated from each cell line, and fused. The fusion reaction can occur without the cytosol under physiological conditions in the presence of energy, appropriate temperature and inner mitochondrial membrane potential. Interestingly, the cytosol was found to modulate the extent of fusion, demonstrating that cell signaling regulates the fusion process. This assay will be very useful for high throughput screening to identify components of the fusion machinery and also pharmacological c

  15. Motor imagery facilitates force field learning

    Microsoft Academic Search

    Muhammad Nabeel Anwar; Naoki Tomi; Koji Ito

    2011-01-01

    Humans have the ability to produce an internal reproduction of a specific motor action without any overt motor output. Recent findings show that the processes underlying motor imagery are similar to those active during motor execution and both share common neural substrates. This suggests that the imagery of motor movements might play an important role in acquiring new motor skills.

  16. Acquired hyperpigmentations*

    PubMed Central

    Cestari, Tania Ferreira; Dantas, Lia Pinheiro; Boza, Juliana Catucci

    2014-01-01

    Cutaneous hyperpigmentations are frequent complaints, motivating around 8.5% of all dermatological consultations in our country. They can be congenital, with different patterns of inheritance, or acquired in consequence of skin problems, systemic diseases or secondary to environmental factors. The vast majority of them are linked to alterations on the pigment melanin, induced by different mechanisms. This review will focus on the major acquired hyperpigmentations associated with increased melanin, reviewing their mechanisms of action and possible preventive measures. Particularly prominent aspects of diagnosis and therapy will be emphasized, with focus on melasma, post-inflammatory hyperpigmentation, periorbital pigmentation, dermatosis papulosa nigra, phytophotodermatoses, flagellate dermatosis, erythema dyschromicum perstans, cervical poikiloderma (Poikiloderma of Civatte), acanthosis nigricans, cutaneous amyloidosis and reticulated confluent dermatitis PMID:24626644

  17. Acquired hyperpigmentations.

    PubMed

    Cestari, Tania Ferreira; Dantas, Lia Pinheiro; Boza, Juliana Catucci

    2014-01-01

    Cutaneous hyperpigmentations are frequent complaints, motivating around 8.5% of all dermatological consultations in our country. They can be congenital, with different patterns of inheritance, or acquired in consequence of skin problems, systemic diseases or secondary to environmental factors. The vast majority of them are linked to alterations on the pigment melanin, induced by different mechanisms. This review will focus on the major acquired hyperpigmentations associated with increased melanin, reviewing their mechanisms of action and possible preventive measures. Particularly prominent aspects of diagnosis and therapy will be emphasized, with focus on melasma, post-inflammatory hyperpigmentation, periorbital pigmentation, dermatosis papulosa nigra, phytophotodermatoses, flagellate dermatosis, erythema dyschromicum perstans, cervical poikiloderma (Poikiloderma of Civatte), acanthosis nigricans, cutaneous amyloidosis and reticulated confluent dermatitis. PMID:24626644

  18. Programmable folding of fusion RNA in vivo and in vitro driven by pRNA 3WJ motif of phi29 DNA packaging motor

    PubMed Central

    Shu, Dan; Khisamutdinov, Emil F.; Zhang, Le; Guo, Peixuan

    2014-01-01

    Misfolding and associated loss of function are common problems in constructing fusion RNA complexes due to changes in energy landscape and the nearest-neighbor principle. Here we report the incorporation and application of the pRNA-3WJ motif of the phi29 DNA packaging motor into fusion RNA with controllable and predictable folding. The motif included three discontinuous ?18 nucleotide (nt) fragments, displayed a distinct low folding energy (Shu D et al., Nature Nanotechnology, 2011, 6:658–667), and folded spontaneously into a leading core that enabled the correct folding of other functionalities fused to the RNA complex. Three individual fragments dispersed at any location within the sequence allowed the other RNA functional modules to fold into their original structures with authentic functions, as tested by Hepatitis B virus ribozyme, siRNA, and aptamers for malachite green (MG), spinach, and streptavidin (STV). Only nine complementary nucleotides were present for any two of the three ?18-nt fragments, but the three 9 bp branches were so powerful that they disrupted other double strands with more than 15 bp within the fusion RNA. This system enabled the production of fusion complexes harboring multiple RNA functionalities with correct folding for potential applications in biotechnology, nanomedicine and nanotechnology. We also applied this system to investigate the principles governing the folding of RNA in vivo and in vitro. Temporal production of RNA sequences during in vivo transcription caused RNA to fold into different conformations that could not be predicted with routine principles derived from in vitro studies. PMID:24084081

  19. Transient loss of motor-evoked responses associated with caudal injection of morphine in a patient with spondylolisthesis undergoing spinal fusion.

    PubMed

    Gibson, Peter R J; Johnston, Sarah; Lagopoulos, Jim; Cummine, John L

    2006-05-01

    A 7-year-old girl having posterior spinal fusion for Grade 3 anterior spondylolisthesis at the L5/S1 level was administered 2.5 mg of morphine in 10 ml saline via the caudal epidural route before surgery. Motor-evoked responses were markedly diminished in her lower limbs for 1 h following this but returned spontaneously. She suffered no neurological injury. The cause for this is postulated to be transient cauda equina compression from the volume of injectate. This complication of caudal injection has not been reported before. The possible mechanisms for this are discussed. We believe that significant L5/S1 spondylolisthesis should be considered a contraindication to the use of caudal epidural injections. PMID:16677268

  20. [Acquired hypertriglyceridemia].

    PubMed

    Takahashi, Manabu; Ishibashi, Shun

    2013-09-01

    Hypertriglyceridemia is associated with an increase in very low density lipoprotein (VLDL), chylomicron, intermediate density lipoprotein(IDL). Acquired hyperlipidemia results from various disorders, such as obesity, diabetes mellitus, alcohol overuse, chronic kidney disease, hypothyroidism, and some drugs like thiazide, -blocker, estrogen, etc. It is important to identify secondary causes underlying hypertriglyceridemia before initiating pharmacotherapy, since management of the causative disorders is the first-line therapy. Even if hyperlipidemia is not controlled after treating the underlying disorders, specific lipid -lowering therapy may be required in addition to lifestyle modification. Fibrate, nicotinic acid and eicosapentaenoic acid are utilized to reduce triglyceride levels. Statin and ezetimibe are utilized if non-high density lipoprotein(HDL)-cholesterol is elevated. PMID:24205720

  1. Acquired epileptiform aphasia.

    PubMed

    Tuchman, R F

    1997-06-01

    The acquired epileptiform aphasias, with Landau-Kleffner's syndrome as the example, represent an important group of syndromes in our quest to understand the relationship between epilepsy, language, and behavior. The controversy that truly frames the literature on the acquired epileptiform aphasias is the role of epileptiform activity on language, behavior, and cognition. This review expands the model of Landau-Kleffner's syndrome to include two other encephalopathies with language and behavioral regression in association with an epileptiform electroencephalogram. Both of these encephalopathies, autistic epileptiform regression and disintegrative epileptiform regression, are associated with an acquired language disorder. The developmental period in which the acquired language disorder begins, the type of language disorder, and the location and type of the epileptiform activity are all important variables that may affect clinical manifestations and prognosis. PMID:9195666

  2. Acquired hepatocerebral degeneration

    PubMed Central

    Renjen, Pushpendra Nath; Khanna, Laxmi; Rastogi, Ruchi; Khan, Nadeem Israr

    2013-01-01

    Acquired (non-Wilsonian) hepatocerebral degeneration is a rare irreversible neurological syndrome that occurs in patients with chronic liver disease associated with multiple metabolic insults. Van Woerkom was the first to describe acquired hepatocerebral degeneration in 1914 followed by the landmark article by Victor et al in 1965. Multiple bouts of hepatic coma are the only known risk factors that trigger this devastating neurodegenerative disease with features suggesting toxic exposure to the brain. Clinically and pathologically the disorder is similar to Wilson's disease although subtle differences in immunostaining of glial fibrillar acidic protein have been documented. Acquired hepatocerebral degeneration occurs in 0.8–2% of patients with cirrhosis. As acquired hepatocerebral degeneration is relatively rare, we are reporting one such case from our hospital in a 50-year-old male patient who had long-standing portal systemic shunt and presented with progressive cognitive decline, bradykinesia, tremors and bilateral extrapyramidal signs. PMID:23780767

  3. Temporal Data Fusion in Multisensor Systems Using Dynamic Time Warping

    Microsoft Academic Search

    Ko Ming Hsiao; Geoff West; Svetha Venkatesh; Mohan Kumar

    Data acquired from multiple sensors can be fused at a variety of levels: the raw data level, the feature level, or the decision level. An additional dimension to the fusion process is temporal fusion, which is fusion of data or information acquired from multiple sensors of different types over a period of time. We propose a technique that can perform

  4. Acquired amegakaryocytic thrombocytopenic purpura.

    PubMed

    Agarwal, Neeraj; Spahr, Joseph E; Werner, Theresa L; Newton, David L; Rodgers, George M

    2006-02-01

    Acquired amegakaryocytic thrombocytopenia is an unusual hematologic disorder characterized by thrombocytopenia in association with markedly diminished bone marrow megakaryocytes. We report a case that responded to treatment with cyclosporine but not to IL-11. The bone marrow biopsy, repeated after resolution of thrombocytopenia, showed normal number of megakaryocytes. PMID:16432869

  5. RELATEDNESS AND ACQUIRER PERFORMANCE

    Microsoft Academic Search

    Lasse B. Lien; Peter G. Klein

    While the strategic management literature suggests that related diversi- fication is superior to unrelated diversification, there is little evidence that acquirers benefit from pursuing related targets. We argue that the em- pirical literature is plagued by poor measures of relatedness. Moreover, many empirical studies do not control adequately for the characteristics of the market for corporate control. We argue that

  6. Developmental contributions to motor sequence learning

    Microsoft Academic Search

    Tal Savion-Lemieux; Jennifer A. Bailey; Virginia B. Penhune

    2009-01-01

    Little is known about how children acquire new motor sequences. In particular, it is not clear if the same learning progression\\u000a observed in adults is also present in childhood nor whether motor skills are acquired in a similar fashion across development.\\u000a In the present study we used the multi-finger sequencing task (MFST), a variant of the serial reaction time (SRT)

  7. Motor Cortex Reorganization across the Lifespan

    ERIC Educational Resources Information Center

    Plowman, Emily K.; Kleim, Jeffrey A.

    2010-01-01

    The brain is a highly dynamic structure with the capacity for profound structural and functional change. Such neural plasticity has been well characterized within motor cortex and is believed to represent one of the neural mechanisms for acquiring and modifying motor behaviors. A number of behavioral and neural signals have been identified that…

  8. Acquired brachial cutaneous dyschromatosis.

    PubMed

    Hu, Stephanie W; Chu, Julie; Meehan, Shane; Kamino, Hideko; Pomeranz, Miriam Keltz

    2011-01-01

    Acquired brachial cutaneous dyschromatosis (ABCD) is a newly described disorder of pigmentary change that occurs on the dorsal aspects of the forearms in post-menopausal women. We report a case of a 62-year-old woman who developed an asymptomatic, reticulated, gray-brown eruption on the dorsal aspects of the forearms of gradual onset that is clinically and histopathologically consistent with ABCD. Whereas the original report found an association between hypertension and/or the use of anti-hypertensive medications in the original cohort, we propose that this entity may, in fact, be associated more closely with cumulative sun damage and may be related to such acquired disorders of the skin as poikiloderma of Civatte. Treatment of these lesions may prove to be a challenge, with an emphasis on rigorous sun protection and adjunctive measures with depigmentating agents, chemical peels, and lasers. PMID:22031642

  9. School Reentry for Children with Acquired Central Nervous Systems Injuries

    ERIC Educational Resources Information Center

    Carney, Joan; Porter, Patricia

    2009-01-01

    Onset of acquired central nervous system (CNS) injury during the normal developmental process of childhood can have impact on cognitive, behavioral, and motor function. This alteration of function often necessitates special education programming, modifications, and accommodations in the education setting for successful school reentry. Special…

  10. Neuropsychological Findings in Congenital and Acquired Childhood Hydrocephalus

    Microsoft Academic Search

    Maria Mataró; Carme Junqué; MariaAntonia Poca; Juan Sahuquillo

    2001-01-01

    Hydrocephalus is an increase in cerebrospinal fluid volume that can be caused by a variety of etiologies. The most common connatal and acquired causes of hydrocephalus are spina bifida, aqueduct stenosis, and preterm low birthweight infants with ventricular hemorrhage. In general, the literature suggests mild neuropsychological deficits associated with hydrocephalus, which are predominant in visuospatial and motor functions, and other

  11. Chronic multifocal demyelinating neuropathy simulating motor neuron disease

    Microsoft Academic Search

    P. Di Bella; F. Logullo; L. Dionisi; M. Danni; M. Scarpelli; F. Angeleri

    1991-01-01

    We describe a patient with a chronic acquired predominantly motor polyneuropathy. His clinical picture initially led to a diagnosis of lower motor neuron form of amyotrophic lateral sclerosis. However electrophysiological examination revealed multifocal, prevalently proximal, conduction blocks at sites not prone to compression. Distinguishing this unusual polyneuropathy from motor neuron diseases is critical, since the former is a potentially, treatable

  12. [Acquired alopecia in childhood].

    PubMed

    Hamm, H

    2013-05-01

    Hair loss and alopecia occur frequently in children. The prevalence of the underlying causes and conditions, treatment options and prognosis differ in part significantly from adulthood. This article focuses on frequent forms of acquired alopecia which are not associated with inflammation or scarring of the scalp. Special attention is given to alopecia areata as the most important entity and to trichotillomania as its most difficult differential diagnosis. Significant forms of diffuse hair loss include anagen-dystrophic and telogen effluvium, androgenetic alopecia and loose anagen hair. PMID:23571647

  13. [Acquired necrotizing myopathies].

    PubMed

    Allenbach, Y; Benveniste, O

    2013-06-01

    Necrotizing myopathies (MN) are defined by a specific histological pattern. They are characterized by a predominant muscle fibre necrosis and regeneration but with little or no associated inflammation. This histological pattern is observed in acquired myopathy but also in muscular dystrophy. Acquired NM can be secondary to drugs or toxics, and if not, autoimmune mechanisms have to be suspected. Necrotizing autoimmune myopathy is recognized as a subgroup of idiopathic inflammatory myopathies, different from other myositides. Generally, patients present a rapidly progressive and severe symmetrical proximal weakness with high serum creatine kinase level, associated in some patients with cardiac involvement. On the other hand, a slower progression may sometimes be observed, that could lead to erroneous diagnosis of muscular dystrophy. Necrotizing autoimmune myopathy may be associated to specific autoantibodies against signal recognition particle, or more recently described, against 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Necrotizing auto-immune myopathy can also be described in association with connective tissue diseases such as lupus or sclerodermia. In remaining cases, cancer association may be observed. Necrotizing autoimmune myopathies are now considered as a new entity, treatable by immunosuppressants and which should not be misdiagnosed as a muscular dystrophy. PMID:22998975

  14. Data fusion for robotic assembly tasks based on human skills

    Microsoft Academic Search

    Rui Cortesão; Ralf Koeppe; Urbano Nunes; Gerd Hirzinger

    2004-01-01

    This work describes a data fusion architecture for robotic assembly tasks based on human sensory-motor skills. These skills are transferred to the robot through geometric and dynamic perception signals. Artificial neural networks are used in the learning process. The data fusion paradigm is addressed. It consists of two independent modules for optimal fusion and filtering. Kalman techniques linked to stochastic

  15. Expression of NR2B in Cerebellar Granule Cells Specifically Facilitates Effect of Motor Training on Motor Learning

    Microsoft Academic Search

    Jianwei Jiao; Akira Nakajima; William G. M. Janssen; Vytautas P. Bindokas; Xiaoli Xiong; John H. Morrison; James R. Brorson; Ya-Ping Tang; Martin Giurfa

    2008-01-01

    It is believed that gene\\/environment interaction (GEI) plays a pivotal role in the development of motor skills, which are acquired via practicing or motor training. However, the underlying molecular\\/neuronal mechanisms are still unclear. Here, we reported that the expression of NR2B, a subunit of NMDA receptors, in cerebellar granule cells specifically enhanced the effect of voluntary motor training on motor

  16. Acquired hepatocerebral degeneration.

    PubMed

    Meissner, Wassilios; Tison, François

    2011-01-01

    Repeated episodes of liver failure or chronic liver cirrhosis may cause acquired (non-Wilsonian) hepatocerebral degeneration (AHCD). Patients with AHCD may show cognitive deficits, ataxia, dysarthria, movement disorders, including parkinsonism, and sometimes myelopathy. Various parenchymal and cholestatic hepatic disorders may result in AHCD. Most patients with AHCD have evidence of portosystemic shunting without necessarily having abnormal liver function. Recent evidence suggests manganese plays a crucial role in the pathogenesis of AHCD. Excess dietary manganese is rapidly cleared by the liver before reaching the systemic circulation. In patients with cirrhosis and portosystemic shunting, manganese bypasses the liver and accumulates in the internal pallidum, while serum manganese levels may be normal or increased. Magnetic resonance imaging abnormalities mainly consist of a signal hyperintensity on T1-weighted images in the internal pallidum. It may also be seen in the putamen, the caudate nucleus, the capsula interna, the mesencephalon, and the cerebellum, and is believed to reflect local manganese accumulation. No specific treatment of AHCD exists. Controlled studies are lacking, but case reports have stressed the usefulness of branched-chain amino acid therapy, trientine, and liver transplantation for the treatment of movement disorders. Levodopa may be efficacious in the treatment of AHCD parkinsonism. PMID:21496578

  17. Molecular motors and their functions in plants

    NASA Technical Reports Server (NTRS)

    Reddy, A. S.

    2001-01-01

    Molecular motors that hydrolyze ATP and use the derived energy to generate force are involved in a variety of diverse cellular functions. Genetic, biochemical, and cellular localization data have implicated motors in a variety of functions such as vesicle and organelle transport, cytoskeleton dynamics, morphogenesis, polarized growth, cell movements, spindle formation, chromosome movement, nuclear fusion, and signal transduction. In non-plant systems three families of molecular motors (kinesins, dyneins, and myosins) have been well characterized. These motors use microtubules (in the case of kinesines and dyneins) or actin filaments (in the case of myosins) as tracks to transport cargo materials intracellularly. During the last decade tremendous progress has been made in understanding the structure and function of various motors in animals. These studies are yielding interesting insights into the functions of molecular motors and the origin of different families of motors. Furthermore, the paradigm that motors bind cargo and move along cytoskeletal tracks does not explain the functions of some of the motors. Relatively little is known about the molecular motors and their roles in plants. In recent years, by using biochemical, cell biological, molecular, and genetic approaches a few molecular motors have been isolated and characterized from plants. These studies indicate that some of the motors in plants have novel features and regulatory mechanisms. The role of molecular motors in plant cell division, cell expansion, cytoplasmic streaming, cell-to-cell communication, membrane trafficking, and morphogenesis is beginning to be understood. Analyses of the Arabidopsis genome sequence database (51% of genome) with conserved motor domains of kinesin and myosin families indicates the presence of a large number (about 40) of molecular motors and the functions of many of these motors remain to be discovered. It is likely that many more motors with novel regulatory mechanisms that perform plant-specific functions are yet to be discovered. Although the identification of motors in plants, especially in Arabidopsis, is progressing at a rapid pace because of the ongoing plant genome sequencing projects, only a few plant motors have been characterized in any detail. Elucidation of function and regulation of this multitude of motors in a given species is going to be a challenging and exciting area of research in plant cell biology. Structural features of some plant motors suggest calcium, through calmodulin, is likely to play a key role in regulating the function of both microtubule- and actin-based motors in plants.

  18. Stepper motor

    NASA Technical Reports Server (NTRS)

    Dekramer, Cornelis

    1994-01-01

    The purpose of this document is to describe the more commonly used permanent magnet stepper motors for spaceflight. It will discuss the mechanical and electrical aspects of the devices, their torque behavior, those parameters which need to be controlled and measured, and test methods to be employed. It will also discuss torque margins, compare these to the existing margin requirements, and determine the applicability of these requirements. Finally it will attempt to generate a set of requirements which will be used in any stepper motor procurement and will fully characterize the stepper motor behavior in a consistent and repeatable fashion.

  19. Sensory data fusion of pressure mattress and wireless inertial magnetic measurement units.

    PubMed

    Rihar, Andraž; Mihelj, Matjaž; Kolar, Janko; Paši?, Jure; Munih, Marko

    2015-02-01

    Head movement of infants is an important parameter for analysing infant motor patterns. Despite its importance, this field has received little sensory-based research in the past years. Therefore, we present a sensory-supported data fusion model for head movement analysis of infants in supine position. The sensory system comprises a pressure mattress and two wireless inertial magnetic measurement units, rendering precise, objective and non-intrusive information on pressure distribution and 3D trunk orientation, respectively. Algorithms first perform pressure data pre-processing and calculate image moments to acquire 2D trunk orientation. Afterwards, unscented Kalman filter is used for sensory data fusion. After additional data processing, head and trunk coordinates are calculated along with head displacement distance. The sensory system was tested on experimental measurements, performed in eight normally developing infants aged from 1 to 5 months. Results of several algorithm combinations were compared to referential video recordings in terms of head lifts. Combination of algorithms, incorporating head tracking and sensory data fusion provides completely accurate results in comparison to normative data. Statistical data analysis and referential optoelectronic measurements were performed to evaluate accuracy of the sensory fusion model. Suitability of the proposed sensory system for head movement analysis of infants in supine position was verified. PMID:25367736

  20. Electric Motors 101

    NSDL National Science Digital Library

    This site from Penton Media includes a number of introductory "mini" lectures on different types of electric motors, including AC motors, DC motors, Servo motors and Stepper motors. The materials also cover electrical drives and other types of small motors. The site includes information about suppliers of electrical motors.

  1. Fusion Basics

    NSDL National Science Digital Library

    This website from the Princeton Plasma Physics Laboratory provides background information about fusion. Different sections cover fusion reactions, plasma heating, and how a fusion power plant would work. In addition, the site offers links to research projects at the Princeton Plasma Physics Laboratory.

  2. Infants with Down Syndrome: Percentage and Age for Acquisition of Gross Motor Skills

    ERIC Educational Resources Information Center

    Pereira, Karina; Basso, Renata Pedrolongo; Lindquist, Ana Raquel Rodrigues; da Silva, Louise Gracelli Pereira; Tudella, Eloisa

    2013-01-01

    The literature is bereft of information about the age at which infants with Down syndrome (DS) acquire motor skills and the percentage of infants that do so by the age of 12 months. Therefore, it is necessary to identify the difference in age, in relation to typical infants, at which motor skills were acquired and the percentage of infants with DS…

  3. Premium Efficient Motors

    E-print Network

    Moser, P. R.

    1984-01-01

    Premium efficient motors are available which convert electrical energy into mechanical energy with fewer losses than the more standard motors. The fewer losses in these motors are due to changes in the motor design and improved manufacturing methods...

  4. Premium Efficient Motors 

    E-print Network

    Moser, P. R.

    1984-01-01

    Premium efficient motors are available which convert electrical energy into mechanical energy with fewer losses than the more standard motors. The fewer losses in these motors are due to changes in the motor design and improved manufacturing methods...

  5. Skill acquisition Motor learning

    E-print Network

    Sergio, Lauren E.

    ·1 Skill acquisition · Motor learning theories ­ closed loop theory ­ schema theory ­ hierarchical theory · Motor learning practice ­ Fitt's three stages ­ motor imagery ­ physical changes Skill acquisition: Closed loop theory · Feedback guides learning a motor skill ­ memory trace selects and initiates

  6. Motor Controllers

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Kollmorgen Corporation's Mermaid II two person submersible is propeller-driven by a system of five DC brushless motors with new electronic controllers that originated in work performed in a NASA/DOE project managed by Lewis Research Center. A key feature of the system is electric commutation rather than mechanical commutation for converting AC current to DC.

  7. Motor Activation From Visible Speech: Evidence From Stimulus Response Compatibility

    Microsoft Academic Search

    Dirk Kerzel; Harold Bekkering

    2000-01-01

    In speech perception, phonetic information can be acquired optically as well as acoustically. The motor theory of speech perception holds that motor control structures are involved in the processing of visible speech, whereas perceptual accounts do not make this assumption. Motor involvement in speech perception was examined by showing participants response-irrelevant movies of a mouth articulating \\/b&Lgr\\/ or \\/d&Lgr\\/ and

  8. Fusion breeder

    SciTech Connect

    Moir, R.W.

    1982-02-22

    The fusion breeder is a fusion reactor designed with special blankets to maximize the transmutation by 14 MeV neutrons of uranium-238 to plutonium or thorium to uranium-233 for use as a fuel for fission reactors. Breeding fissile fuels has not been a goal of the US fusion energy program. This paper suggests it is time for a policy change to make the fusion breeder a goal of the US fusion program and the US nuclear energy program. The purpose of this paper is to suggest this policy change be made and tell why it should be made, and to outline specific research and development goals so that the fusion breeder will be developed in time to meet fissile fuel needs.

  9. Fusion Implementation

    SciTech Connect

    J.A. Schmidt

    2002-02-20

    If a fusion DEMO reactor can be brought into operation during the first half of this century, fusion power production can have a significant impact on carbon dioxide production during the latter half of the century. An assessment of fusion implementation scenarios shows that the resource demands and waste production associated with these scenarios are manageable factors. If fusion is implemented during the latter half of this century it will be one element of a portfolio of (hopefully) carbon dioxide limiting sources of electrical power. It is time to assess the regional implications of fusion power implementation. An important attribute of fusion power is the wide range of possible regions of the country, or countries in the world, where power plants can be located. Unlike most renewable energy options, fusion energy will function within a local distribution system and not require costly, and difficult, long distance transmission systems. For example, the East Coast of the United States is a prime candidate for fusion power deployment by virtue of its distance from renewable energy sources. As fossil fuels become less and less available as an energy option, the transmission of energy across bodies of water will become very expensive. On a global scale, fusion power will be particularly attractive for regions separated from sources of renewable energy by oceans.

  10. Making acquired physician practices profitable.

    PubMed

    Bolinger, J E; Hough, D E

    1997-02-01

    Many healthcare organizations that acquire physician practices do not realize a return on their investments. Instead, acquisitions often create excess capacity, drive up costs, and reduce an organization's ability to attract managed care contracts. Healthcare systems that acquire physician practices can help ensure that the acquisitions will be profitable by recognizing the benefits and eliminating the barriers to integration, developing a shared strategic vision, developing a progressive governance policy, implementing sound financial management, and achieving critical mass over which to spread fixed costs. PMID:10164880

  11. Rotary protein motors.

    PubMed

    Oster, George; Wang, Hongyun

    2003-03-01

    Three protein motors have been unambiguously identified as rotary engines: the bacterial flagellar motor and the two motors that constitute ATP synthase (F(0)F(1) ATPase). Of these, the bacterial flagellar motor and F(0) motors derive their energy from a transmembrane ion-motive force, whereas the F(1) motor is driven by ATP hydrolysis. Here, we review the current understanding of how these protein motors convert their energy supply into a rotary torque. PMID:12628343

  12. Assisted fusion

    E-print Network

    German Kälbermann

    2009-10-19

    A model of nuclear fusion consisting of a wave packet impinging into a well located between square one dimensional barriers is treated analytically. The wave function inside the well is calculated exactly for the assisted tunneling induced by a perturbation mimicking a constant electric field with arbitrary time dependence. Conditions are found for the enhancement of fusion.

  13. Image fusion

    NASA Technical Reports Server (NTRS)

    Pavel, M.

    1993-01-01

    The topics covered include the following: a system overview of the basic components of a system designed to improve the ability of a pilot to fly through low-visibility conditions such as fog; the role of visual sciences; fusion issues; sensor characterization; sources of information; image processing; and image fusion.

  14. Acquired strabismus following cosmetic blepharoplasty.

    PubMed

    Syniuta, Laura A; Goldberg, Robert A; Thacker, Neepa M; Rosenbaum, Arthur L

    2003-05-01

    The purpose of this study was to report on 12 patients with acquired strabismus following cosmetic blepharoplasty and to identify patterns of strabismus related to the surgical procedure. Clinical ophthalmologic examinations were performed to specifically clarify the type of strabismus. Operative reports of the blepharoplasty procedures were reviewed. Patients were followed for a minimum of 3 months after the blepharoplasty procedure before surgical intervention was considered. Operative findings at corrective strabismus surgery were noted and an attempt was made to correlate these findings with the clinical ophthalmologic examination and the blepharoplasty surgical procedure. Twelve cases of persistent vertical strabismus occurred following blepharoplasty procedures. Five patients had clinical findings consistent with the diagnosis of acquired superior oblique palsy; one of these five patients also showed signs of an acquired Brown syndrome. Seven patients developed an incomitant vertical deviation consistent with an inferior rectus paresis. Strabismus occurred after conventional lower lid, upper lid, and four-lid blepharoplasty with or without laser blepharoplasty. Acquired strabismus accompanied by persistent diplopia may occur as a complication of cosmetic blepharoplasty. Extraocular muscle damage resulting in either superior oblique muscle palsy or inferior rectus paresis was noted in these patients. In some cases, patients with inferior rectus paresis also showed mechanical restriction to upward rotation of the globe. PMID:12711971

  15. Acquired Equivalence Changes Stimulus Representations

    ERIC Educational Resources Information Center

    Meeter, M.; Shohamy, D.; Myers, C. E.

    2009-01-01

    Acquired equivalence is a paradigm in which generalization is increased between two superficially dissimilar stimuli (or antecedents) that have previously been associated with similar outcomes (or consequents). Several possible mechanisms have been proposed, including changes in stimulus representations, either in the form of added associations or…

  16. Acquiring Procedural Knowledge in EXPECT

    Microsoft Academic Search

    Yolanda Gil; Jim Blythe; Jihie Kim; Surya Ramachandran

    2000-01-01

    The EXPECT project has focused on acquiring problem- solving knowledge for users for the last decade, using an expressive language that is open to inspection. Our aim has been to alleviate the bottleneck in creating knowledge-based systems by providing support for both knowledge engineers and end users to specify problem-solving knowledge. In this paper we summarize selected areas of current

  17. Motor Effect

    NSDL National Science Digital Library

    The Exploratorium

    2012-06-26

    In this activity about electricity and magnetism, learners examine what happens when a magnet exerts a force on a current-carrying wire. Using a simple device, learners discover that when an electrical current flows through a magnetic field, a force is exerted on the current and this force can be used to make an electric motor. Learners will experiment to find out what happens when they reverse the direction of current flow. They will also discover a mathematical tool called the "right-hand rule."

  18. Lateral Transpsoas Fusion: Indications and Outcomes

    PubMed Central

    Patel, Vishal C.; Park, Daniel K.; Herkowitz, Harry N.

    2012-01-01

    Spinal fusion historically has been used extensively, and, recently, the lateral transpsoas approach to the thoracic and lumbar spine has become an increasingly common method to achieve fusion. Recent literature on this approach has elucidated its advantage over more traditional anterior and posterior approaches, which include a smaller tissue dissection, potentially lower blood loss, no need for an access surgeon, and a shorter hospital stay. Indications for the procedure have now expanded to include degenerative disc disease, spinal stenosis, degenerative scoliosis, nonunion, trauma, infection, and low-grade spondylolisthesis. Lateral interbody fusion has a similar if not lower rate of complications compared to traditional anterior and posterior approaches to interbody fusion. However, lateral interbody fusion has unique complications that include transient neurologic symptoms, motor deficits, and neural injuries that range from 1 to 60% in the literature. Additional studies are required to further evaluate and monitor the short- and long-term safety, efficacy, outcomes, and complications of lateral transpsoas procedures. PMID:23213303

  19. Multifocal Motor Neuropathy

    MedlinePLUS

    ... Diversity Find People About NINDS NINDS Multifocal Motor Neuropathy Information Page Table of Contents (click to jump ... done? Clinical Trials Organizations What is Multifocal Motor Neuropathy? Multifocal motor neuropathy is a progressive muscle disorder ...

  20. Hereditary and acquired polyneuropathy conditions of the peripheral nerves: clinical considerations and MR neurography imaging.

    PubMed

    Trivedi, Jaya R; Phillips, Lauren; Chhabra, Avneesh

    2015-04-01

    Polyneuropathies can be classified as either primarily demyelinating or axonal, and further as hereditary or acquired. It is important to recognize acquired neuropathies because some are amenable to treatment. Clinical findings and electrophysiology are used in the routine diagnosis of these conditions. Magnetic resonance neurography (MRN) is a helpful supplementary diagnostic tool. This article discusses the typical clinical findings, electrophysiology findings, and MRN appearances of common hereditary or acquired neuropathies such as chronic inflammatory demyelinating neuropathy, multifocal motor neuropathy, diabetic neuropathy, chemotherapy-induced neuropathy, and postsurgical neuropathy. PMID:25764237

  1. Implementing Motor Decision Plans 

    E-print Network

    Elliott, R. N.

    2001-01-01

    , like Energy-Efficient Electric Motor Selection Handbook (McCoy, Litman, & Doullass 1993) or a tool, like the MotorMaster+ computer program (WSU 1999)-both available through DOE's BestPractices Motor Systems program-can provide some guidance... when a motor fails and must either be replaced or repaired. This is represented visually in Figure 1. When purchasing a motor for a new application, time is usually available to consider various options. However, once a motor has failed...

  2. Cerebral magnetic resonance image segmentation using data fusion

    Microsoft Academic Search

    Jagath C. Rajapakse; J. N. Giedd; A. L. Krain; S. D. Hamburger; J. L. Rapoport; C. DeCarli

    1996-01-01

    A semiautomated method is described for segmenting dual echo MR head scans into gray and white matter and CSF. The method is applied to brain scans of 80 healthy children and adolescents. A probabilistic data fusion equation was used to combine simultaneously acquired T2-weighted and proton density head scans for tissue segmentation. The fusion equation optimizes the probability of a

  3. Fusion Power.

    ERIC Educational Resources Information Center

    Dingee, David A.

    1979-01-01

    Discusses the extraordinary potential, the technical difficulties, and the financial problems that are associated with research and development of fusion power plants as a major source of energy. (GA)

  4. Spinal fusion

    MedlinePLUS

    ... the spine. Other surgery, such as a diskectomy , laminectomy , or a foraminotomy , is almost always done first. ... procedures for spinal stenosis , such as foraminotomy or laminectomy After diskectomy in the neck Spinal fusion may ...

  5. Data fusion for the detection of buried land mines

    SciTech Connect

    Clark, G.A.; Sengupta, S.K.; Schaich, P.C.; Sherwood, R.J.; Buhl, M.R.; Hernandez, J.E.; Kane, R.J.; Barth, M.J.; Fields, D.J.; Carter, M.R.

    1993-10-01

    The authors conducted experiments to demonstrate the enhanced delectability of buried land mines using sensor fusion techniques. Multiple sensors, including imagery, infrared imagery, and ground penetrating radar, have been used to acquire data on a number of buried mines and mine surrogates. The authors present this data along with a discussion of the application of sensor fusion techniques for this particular detection problem. The authors describe the data fusion architecture and discuss some relevant results of these classification methods.

  6. Fusion Simulation

    NSDL National Science Digital Library

    In this activity, kids are able to see with their own eyes how fusion works. The simple experiment requires only Velcro and two strong magnets.The activity begins with a brief overview that introduces students to the science they are about to see. Then, the procedure is laid out in simple step-by-step directions. The activity ends with an explanation that gives students a deeper understanding of how what they've just witnessed relates to fusion.

  7. Possibilistic Fusion for Landcover Mapping using Correlated Satellite Imagery for Environmental Change

    Microsoft Academic Search

    SHAHEERA RASHWAN

    2006-01-01

    To acquire detection performance required for an operational system in the detection for satellite image for environmental change, it is necessary to use multiple images over years to know the environmental changes over years. This paper describes a method for decision-level fusion technique where the fusion can compensate for correlation among images. The fusion is done using possibilistic combiners based

  8. Myopathy in acquired partial lipodystrophy.

    PubMed

    Orrell, R W; Peatfield, R C; Collins, C E; Woodrow, D F; Moss, J; Press, M; Lane, R J

    1995-05-01

    We describe two women with acquired partial lipodystrophy, one with significant myopathic symptoms and signs. Muscle biopsy of deltoid and quadriceps was performed in each case. The light microscopy findings were of type 1 and type 2 fibre hypertrophy, with an increase in intracytoplasmic fat in both cases. Electron microscopy showed normal fibres, with accumulations of electron-lucent fat droplets between the myofibrils. The cause of the lipodystrophies is uncertain, but myopathy may be a feature, and muscle biopsy studies may help in further defining the syndrome. PMID:7656496

  9. Motor current signature analysis

    Microsoft Academic Search

    P. Pillay; Z. Xu

    1996-01-01

    This paper shows how the speed of an induction motor (IM) can be extracted from the motor currents of an induction motor with a Labview implementation of motor current signature analysis (MCSA). The implementation is first applied to an IM driven by the 60 Hz mains. The estimation system consists of data acquisition, demodulation, and FFT spectrum analyses. The estimation

  10. Gross Motor Development.

    ERIC Educational Resources Information Center

    Florida Learning Resources System/CROWN, Jacksonville.

    The document is designed to help teachers identify and remediate gross motor development deficits in elementary school students. A definition of gross motor development and a checklist of gross motor skills are provided. Sections cover the following topics: successful teaching techniques; activities for perceptual-motor training; activities for…

  11. Investigating motors and magnetism.

    NSDL National Science Digital Library

    David Reierson

    This activity is an activity where students build a motor, learn motor operation and theory, interpret their understanding through troubleshooting, and develop a new, experimental question related to the motor. One follow-up activity would be coupling their motor to a fan blade or other axle to convert electrical energy to magnetic energy into mechanical motion for real world application.

  12. Motor vehicle

    SciTech Connect

    Furukawa, Y.; Sano, S.

    1986-04-15

    An improvement in a motor vehicle is described including: a vehicle body; a front road wheel disposed in the front part of the vehicle body; a rear road wheel disposed in the rear part of the vehicle body; an engine for driving at least either of the front and rear road wheels; and a steering wheel for steering at least either of the front and rear road wheels; comprising: detection means connected to the vehicle for detecting the transverse sliding angle of the vehicle body; and display means connected to the detection means for visually displaying the moving direction of the vehicle body on the basis of an output of the detection means; and the detection means comprises a first sensor for detecting the advancing speed of the vehicle, a second sensor for detecting the transverse acceleration of the vehicle, a third sensor for detecting the yawing velocity of the vehicle, and a processor for calculating the transverse sliding angle on the basis of the advancing speed, the transverse acceleration and the yawing velocity.

  13. 7 CFR 989.17 - Acquire.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE RAISINS PRODUCED FROM GRAPES GROWN IN CALIFORNIA Order Regulating Handling Definitions § 989.17 Acquire. Acquire means to have or...

  14. 7 CFR 989.17 - Acquire.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE RAISINS PRODUCED FROM GRAPES GROWN IN CALIFORNIA Order Regulating Handling Definitions § 989.17 Acquire. Acquire means to have or...

  15. Acquiring Innovation Knowledge Peter Busch, Debbie Richards

    E-print Network

    Richards, Debbie

    Acquiring Innovation Knowledge Peter Busch, Debbie Richards Computing Department, Division,richards}@ics.mq.edu.au Abstract: There are few possibilities for acquiring knowledge related to innovation. Firstly, acquiring impractical when it comes to innovation knowledge. While innovation is recognized as a vital part

  16. Towards Motor Skill Learning for Robotics

    Microsoft Academic Search

    Jan Peters; Katharina Mülling; Jens Kober; Duy Nguyen-Tuong; Oliver Krömer

    \\u000a Learning robots that can acquire new motor skills and refine existing one has been a long standing vision of robotics, artificial\\u000a intelligence, and the cognitive sciences. Early steps towards this goal in the 1980s made clear that reasoning and human insights\\u000a will not suffice. Instead, new hope has been offered by the rise of modern machine learning approaches. However, to

  17. Cold fusion, Alchemist's dream

    SciTech Connect

    Clayton, E.D.

    1989-09-01

    In this report the following topics relating to cold fusion are discussed: muon catalysed cold fusion; piezonuclear fusion; sundry explanations pertaining to cold fusion; cosmic ray muon catalysed cold fusion; vibrational mechanisms in excited states of D{sub 2} molecules; barrier penetration probabilities within the hydrogenated metal lattice/piezonuclear fusion; branching ratios of D{sub 2} fusion at low energies; fusion of deuterons into {sup 4}He; secondary D+T fusion within the hydrogenated metal lattice; {sup 3}He to {sup 4}He ratio within the metal lattice; shock induced fusion; and anomalously high isotopic ratios of {sup 3}He/{sup 4}He.

  18. Data fusion

    Microsoft Academic Search

    Jens Bleiholder; Felix Naumann

    2008-01-01

    The development of the Internet in recent years has made it possible and useful to access many different information systems anywhere in the world to obtain information. While there is much research on the integration of heterogeneous information systems, most commercial systems stop short of the actual integration of available data. Data fusion is the process of fusing multiple records

  19. [Motor control by the basal ganglia].

    PubMed

    Takakusaki, Kaoru

    2009-06-01

    The cerebral cortex controls cognitive and voluntary process of movements. The brainstem and spinal cord are involved in the execution of innately acquired motor patterns such as postural reflexes, muscle tone regulation and locomotion. Cortico-reticular projections arising from the motor cortical areas contribute to the postural control that precedes the voluntary movement process. The basal ganglia cooperatively regulates the activities of the cerebral cortex and the brainstem-spinal cord by its strong inhibitory and dis-inhibitory effects upon these target structures so that goal-directed movements could be appropriately performed. We propose that basal ganglia disfunction, including the abnormality in the dopaminergic projection system, may disturb the cooperative regulation, resulting in motor deficiencies expressed in basal diseases. PMID:19618841

  20. 17 CFR 210.8-06 - Real estate operations acquired or to be acquired.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...2014-04-01 2014-04-01 false Real estate operations acquired or to be acquired...Reporting Companies § 210.8-06 Real estate operations acquired or to be acquired...limited to, competition in the rental market, comparative rents,...

  1. 17 CFR 210.8-06 - Real estate operations acquired or to be acquired.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...2011-04-01 2011-04-01 false Real estate operations acquired or to be acquired...Reporting Companies § 210.8-06 Real estate operations acquired or to be acquired...limited to, competition in the rental market, comparative rents,...

  2. 17 CFR 210.8-06 - Real estate operations acquired or to be acquired.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...2013-04-01 2013-04-01 false Real estate operations acquired or to be acquired...Reporting Companies § 210.8-06 Real estate operations acquired or to be acquired...limited to, competition in the rental market, comparative rents,...

  3. 17 CFR 210.8-06 - Real estate operations acquired or to be acquired.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...2012-04-01 2012-04-01 false Real estate operations acquired or to be acquired...Reporting Companies § 210.8-06 Real estate operations acquired or to be acquired...limited to, competition in the rental market, comparative rents,...

  4. PROGRESS TOWARD UNDERSTANDING MAGNETIZED TARGET FUSION (MTF).

    SciTech Connect

    Kirkpatrick, R. C. (Ronald C.); Lindemuth, I. R. (Irvin R.); Barnes, D. C. (Daniel C.); Faehl, R. J. (Rickey J.); Sheehey, P. T. (Peter T.); Knapp, C. E. (Charles E.)

    2001-01-01

    Magnetized target fusion (MTF) takes advantage of (1) the reduction of the electron thermal conductivity in a plasma due to magnetization and (2) the efficient heating through bulk compression. MTF proposes to create a warm plasma with an embedded magnetic field and to compress it using an imploded liner or shell. The minimum energy required for fusion in an optimized target is directly proportional to the mass of the ignited fusion fuel. Simple theoretical arguments and parameter studies have demonstrated that MTF has the potential for significantly reducing the power and intensity of a target driver needed to achieve fusion. In order to acquire a comprehensive understanding of MTF and its potential applications it is prudent to develop more complete and reliable computational techniques. This paper briefly reviews the progress toward that goal.

  5. Implementing Motor Management 

    E-print Network

    Colip, R. L.

    2002-01-01

    Electric motors account for sixty five percent of industrial energy consumed today. There are many opportunities to conserve electricity by using more energy efficient motors and drives. Proven technologies and practices can reduce energy...

  6. Brushless Motor Parameter Optimization

    E-print Network

    Ruina, Andy L.

    ~ 1 ~ Brushless Motor Parameter Optimization Report Spring 2011 May 6, 2011 Alicia Violeta Juarez Crow ECE 2012 1439 Kentfield Ave. Apt. 2 Redwood City, CA 94061 (650)3957846 avj22 ........................................................................................................................ 7 A. Motor

  7. Chronic motor tic disorder

    MedlinePLUS

    Chronic vocal tic disorder; Tic - chronic motor tic disorder ... Chronic motor tic disorder is more common than Tourette syndrome . Chronic tics may be forms of Tourette syndrome. Tics usually start ...

  8. Stepping Motor Control System

    E-print Network

    Larson, Noble G.

    This paper describes a hardware system designed to facilitate position and velocity control of a group of eight stepping motors using a PDP-11. The system includes motor driver cards and other interface cards in addition ...

  9. Functional diversity of ES cell derived motor neuron subtypes revealed through intraspinal transplantation

    PubMed Central

    Peljto, Mirza; Dasen, Jeremy S.; Mazzoni, Esteban O.; Jessell, Thomas M.; Wichterle, Hynek

    2010-01-01

    Summary Cultured ES cells can form different classes of neurons, but whether these neurons can acquire specialized subtype features typical of neurons in vivo remains unclear. We show here that mouse ES cells can be directed to form highly specific motor neuron subtypes in the absence of added factors, through a differentiation program that relies on endogenous Wnts, FGFs, and Hh – mimicking the normal program of motor neuron subtype differentiation. Molecular markers that characterize motor neuron subtypes anticipate the functional properties of these neurons in vivo: ES motor neurons grafted isochronically into chick spinal cord settle in appropriate columnar domains and select axonal trajectories with a fidelity that matches that of their in vivo generated counterparts. ES motor neurons can therefore be programmed in a predictive manner to acquire molecular and functional properties that characterize one of the many dozens of specialized motor neuron subtypes that exist in vivo. PMID:20804971

  10. Acquired immune deficiency syndrome: review.

    PubMed

    Scully, C; Cawson, R A; Porter, S R

    1986-07-19

    Acquired immunodeficiency syndrome (AIDS) is reviewed for dental practitioners, with an emphasis on oral findings; the clinical course, diagnosis, reporting, treatment, prognosis, transmission, and epidemiology are also covered. HIV infection has an incubation period that may be associated with glandular fever, a prodrome called AIDS-Related Complex (ARC) characterized by lymphadenopathy, low fever, weight loss, night sweats, diarrhea, oral candidosis, nonproductive cough and recurrent infections. AIDS is characterized by opportunistic infections. Over 50% present with pneumocystis carinii pneumonia, 21% with Kaposi's sarcoma, and 6% have both. The AIDS virus causes direct neurological symptoms in some cases. Oral candidosis (thrush) in a young male without a local cause such as xerostomia or immune suppression is strongly suggestive of AIDS. Other oral manifestations are severe herpes simplex, varicella-zoster, Epstein-Barr virus, cytomegalovirus, venereal warts, aphthous ulceration, mycobacterial oral ulcers, oral histoplasmosis, sinusitis and osteomyelitis of the jaw. Hairy leukoplakia, usually seen on the lateral border of the tongue, is probably caused by Epstein-Barr virus. Kaposi's sarcoma, an endothelial cell tumor, is characteristic of AIDS, and in 50% of patients is oral or perioral. Cervical lymph node enlargement will be seen in those with ARC as well as AIDS. No guidelines have been issued by the Department of Health and Social Security for dental surgeons in the UK for reporting AIDS cases. Although HIV virions have been isolated from saliva, there are no known incidents of transmission via saliva. HIV is less likely to be transmitted by needle stick injuries than, for example hepatitis B (25% risk), especially if the blood is from a carrier rather than a full blown AIDS case. PMID:3524629

  11. Servo and Stepper Motors

    NSDL National Science Digital Library

    Thomas, Fred

    In this lesson from Math Machines, students will "compare and contrast hobby servo motors and small stepper motors in terms of the type and range of motion, precision, feedback and speed." The exercise is divided into two parts, the first dedicated to servo motors and the second to stepper motors. Step by step instructions are included for each section. A participant handout (including worksheets) and facilitator notes are made available for download in DOC file format. Links to calculator programs are also included.

  12. Why electric motors fail

    SciTech Connect

    Strugar, D. (Reliance Electric Co., Chicago, IL (United States)); Weiss, R. (Reliance Electric Co., Cleveland, OH (United States))

    1994-07-01

    Operated long enough, all motors eventually fail. This inevitable failure, however, is deferred significantly by eliminating or minimizing the most common causes of motor failure. These causes are dust and other solid contaminants, chemical attack, moisture, overloading, high ambient operating temperature, undervoltage, overvoltage, voltage unbalance, voltage surges, and vibration. The paper presents a review on the most prevalent causes of motor failure, and information on what you can do to extend motor life.

  13. Fourier analysis of motor current for diagnosis of broken bars in squirrel-cage induction machines

    Microsoft Academic Search

    Mohammad Rezazadeh Mehrjou; Norman Mariun; Mohammad Hamiruce Marhaban; Norhisam Misron

    2010-01-01

    Condition monitoring, signal processing and data analysis are the key parts of the induction machine (IM) fault detection scheme. Frequency analysis of the signal acquired through the condition monitoring is commonly applied for motor fault detection. This paper is intended to investigate the ability and effectiveness of Fourier analysis of motor current for broken rotor bar detection. Accordingly, the current

  14. Electrical Motor Current Signal Analysis using a Dynamic Time Warping Method for Fault Diagnosis

    Microsoft Academic Search

    D. Zhen; A. Alibarbar; X. Zhou; F. Gu; A. D. Ball

    2011-01-01

    This paper presents the analysis of phase current signals to identify and quantify common faults from an electrical motor based on dynamic time warping (DTW) algorithm. In condition monitoring, measurements are often taken when the motor undertakes varying loads and speeds. The signals acquired in these conditions show similar profiles but have phase shifts, which do not line up in

  15. Developing Language in a Developing Body: The Relationship between Motor Development and Language Development

    ERIC Educational Resources Information Center

    Iverson, Jana M.

    2010-01-01

    During the first eighteen months of life, infants acquire and refine a whole set of new motor skills that significantly change the ways in which the body moves in and interacts with the environment. In this review article, I argue that motor acquisitions provide infants with an opportunity to practice skills relevant to language acquisition before…

  16. Nuclear Fusion

    NSDL National Science Digital Library

    Astronomical Society of the Pacific

    2008-01-01

    This simple and engaging astronomy activity explains nuclear fusion and how radiation is generated by stars, using marshmallows as a model. Learners will explore what cosmic radiation is and where it comes from, and how the elements in the universe are generated. The PDF contains step-by-step instructions, photos, presentation tips, links to background information, and a printable Periodic Table of the Elements.

  17. Distributed information fusion agents

    Microsoft Academic Search

    Don Perugini; Dale Lambert; Leon Sterling; Adrian Pearce

    2003-01-01

    Information fusion is typically data driven and applied to adversarial contexts. Advantages of a goal driven fusion process are emerging. An agent approach to fusion applied to friendly contexts, such as logistics, is presented. Agents are suitable for fusion because they can represent autonomous fusion eritities by modelling their capabilities, expertise and intentions. This paper promotes a level 3 centric

  18. Motor bearing fluting

    Microsoft Academic Search

    J. A. Lawson

    1993-01-01

    Electrical motor bearing fluting has been defined as damage due to electrical current discharge through a motor bearing. Bearing race metal is electroplated onto the bearing balls. Close inspection reveals microscopic pits on bearing ball and race surfaces. A DC motor frame was completely isolated from ground except by a single grounding conductor with applied armature and field voltage. No

  19. Motor Oil Classification Based on Time-Resolved Fluorescence

    PubMed Central

    Mu, Taotao; Chen, Siying; Zhang, Yinchao; Guo, Pan; Chen, He; Meng, Fandong

    2014-01-01

    A time-resolved fluorescence (TRF) technique is presented for classifying motor oils. The system is constructed with a third harmonic Nd:YAG laser, a spectrometer, and an intensified charge coupled device (ICCD) camera. Steady-state and time-resolved fluorescence (TRF) measurements are reported for several motor oils. It is found that steady-state fluorescence is insufficient to distinguish the motor oil samples. Then contour diagrams of TRF intensities (CDTRFIs) are acquired to serve as unique fingerprints to identify motor oils by using the distinct TRF of motor oils. CDTRFIs are preferable to steady-state fluorescence spectra for classifying different motor oils, making CDTRFIs a particularly choice for the development of fluorescence-based methods for the discrimination and characterization of motor oils. The two-dimensional fluorescence contour diagrams contain more information, not only the changing shapes of the LIF spectra but also the relative intensity. The results indicate that motor oils can be differentiated based on the new proposed method, which provides reliable methods for analyzing and classifying motor oils. PMID:24988439

  20. Imitating Chemical Motors with Optimal Information Motors

    NASA Astrophysics Data System (ADS)

    Horowitz, Jordan M.; Sagawa, Takahiro; Parrondo, Juan M. R.

    2013-07-01

    To induce transport, detailed balance must be broken. A common mechanism is to bias the dynamics with a thermodynamic fuel, such as chemical energy. An intriguing, alternative strategy is for a Maxwell demon to effect the bias using feedback. We demonstrate that these two different mechanisms lead to distinct thermodynamics by contrasting a chemical motor and information motor with identical dynamics. To clarify this difference, we study both models within one unified framework, highlighting the role of the interaction between the demon and the motor. This analysis elucidates the manner in which information is incorporated into a physical system.

  1. data fusion 15 June 2012

    E-print Network

    Dobigeon, Nicolas

    real world data fusion Fred Daum 15 June 2012 data fusion Copyright © 2012 Raytheon Company. All fusion fusion of measurements performance fusion of tracks interesting parameter 3 #12;real world multi-sensor data fusion fusion of tracks performance fusion of measurements interesting parameter 4 #12;real world

  2. Inspection, maintenance and repair of motor vehicles. Subject bibliography

    SciTech Connect

    Flynn, L.

    1980-08-01

    This bibliography represents literature concerning the inspection, maintenance and repair of motor vehicles which has been acquired since the establishment of the National Highway Traffic Safety Administration in 1967. Citations follow the format used in the monthly abstract journal Highway Safety Literature and are indexed by a key-word-out-of-context (KWOC) listing, author, corporate author, contract number, and report number.

  3. A modified instantaneous speed observer design for brushless AC motors

    Microsoft Academic Search

    Ming-Shyan Wang; Po-Jui Hsiao; Nguyen Thi Hanh

    2010-01-01

    Low speed control of servo systems is required in some applications. Motor speed is generally acquired from the so-called M method, which averages the number of pulses from the coupled encoder by a fixed time period. As a result, a long detection delay time, due to speeds lower than the minimum measurable value determined by the sampling frequency and the

  4. Replacing Motors Counting Savings: Results from a 100 Motor Study

    E-print Network

    Kaufman, N. M.

    2006-01-01

    REPLACING MOTORS, COUNTING SAVINGS: RESULTS FROM A 100 MOTOR STUDY Nicole M. Kaufman Motor Systems Engineer Advanced Energy Raleigh, NC ABSTRACT Software tools such as MotorMaster+ aid facility personnel in conducting payback... analyses for replacing motors. These tools make assumptions on the motors’ operational efficiency in their calculations. By observing 100 pre-EPCA (Energy Policy & Conservation Act) motors in operation, removing them from service and conducting IEEE...

  5. Replacing Motors Counting Savings: Results from a 100 Motor Study 

    E-print Network

    Kaufman, N. M.

    2006-01-01

    REPLACING MOTORS, COUNTING SAVINGS: RESULTS FROM A 100 MOTOR STUDY Nicole M. Kaufman Motor Systems Engineer Advanced Energy Raleigh, NC ABSTRACT Software tools such as MotorMaster+ aid facility personnel in conducting payback... analyses for replacing motors. These tools make assumptions on the motors’ operational efficiency in their calculations. By observing 100 pre-EPCA (Energy Policy & Conservation Act) motors in operation, removing them from service and conducting IEEE...

  6. Acquired Alexia With Agraphia Syndrome in Childhood

    Microsoft Academic Search

    Philippe F. Paquier; Hyo Jung De Smet; Peter Mariën; Nathalie Poznanski; Patrick Van Bogaert

    2006-01-01

    The acquired alexia with agraphia syndrome is a conspicuous disorder of reading and writing in the absence of significant other language impairments that has mainly been recorded in adults. Pure cases are rare, with most patients displaying mild aphasic deficits. In children, acquired reading and writing disorders are generally reported as part of more encompassing aphasic syndromes affecting oral and

  7. ACQUIRED EQUIVALENCE CHANGES STIMULUS REPRESENTATIONS , D. SHOHAMY

    E-print Network

    Shohamy, Daphna

    ACQUIRED EQUIVALENCE CHANGES STIMULUS REPRESENTATIONS M. MEETER 1 , D. SHOHAMY 2 , AND C.E. MYERS 3 UNIVERSITY 3 DEPT. OF PSYCHOLOGY, RUTGERS UNIVERSITY Acquired equivalence is a paradigm in which, including changes in stimulus representations, either in the form of added associations or a change

  8. Occipitocervical fusion.

    PubMed

    Garrido, Ben J; Sasso, Rick C

    2012-01-01

    The evolution of occipitocervical fixation and new rigid universal screw-rod construct technology has allowed secure anchorage at each level of the occipitocervical junction with the elimination of rigid external orthoses. Rigid occipitocervical instrumentation constructs have achieved higher fusion rates and less postoperative immobilization-associated complications. Outcomes have improved compared with former nonrigid instrumentation techniques; however, with advances of rigid occipitocervical stabilization capability have come new challenges, risks, and operative techniques. A thorough understanding of the relevant cervical bony and soft tissue anatomy is essential for safe implantation and a successful outcome. PMID:22082624

  9. Acquired Chiari malformation secondary to atlantoaxial vertical subluxation in a patient with rheumatoid arthritis combined with atlanto-occipital assimilation.

    PubMed

    Kimura, Yuiko; Seichi, Atsushi; Gomi, Akira; Kojima, Masahiro; Inoue, Hirokazu; Kimura, Atsushi

    2012-01-01

    A 65-year-old woman with a history of rheumatoid arthritis presented with a rare case of acquired Chiari malformation secondary to atlantoaxial vertical subluxation, associated with congenital atlanto-occipital assimilation. Syringomyelia and tetraparesis improved immediately after posterior fossa decompression and simultaneous occipito-cervical junction fusion. The progression of acquired Chiari malformation is not well known. We concluded that coexisting assimilation accelerated crowded foramen magnum following atlantoaxial vertical subluxation and induced acquired Chiari malformation over the course of a few years. PMID:23006887

  10. Acquired lumbar stenosis: topic review and a case series.

    PubMed

    Jane, J A; DiPierro, C G; Helm, G A; Shaffrey, C I; Jane, J A

    1997-08-15

    Stenosis of the central and lateral lumbar vertebral canal can be congenital or acquired; the latter is most often caused by a degenerative process. The associated neurogenic claudication and/or radiculopathic symptom complexes are thought to result from compression of the cauda equina and lumbosacral nerve roots by hypertrophy of or encroachment by any combination of the following: canal walls, ligamenta flava, intervertebral discs, posterior longitudinal ligament, or epidural fat. The authors' technique for the treatment of lumbar stenosis involves extensive unilateral decompression with undercutting of the spinous process and obviates the need for instrumentation by using a contralateral autologous bone fusion. The results in a series of 29 patients in whom the procedure was performed suggest that this decompression method safely and successfully treats not only the radicular symptoms caused by lateral stenosis but also the neurogenic claudication symptoms associated with central stenosis. In addition, the procedure can preserve spinal stability without instrumentation by using contralateral autologous bone fusion along the laminae and spinous processes. PMID:15104424

  11. Acquired poikiloderma: proposed classification and diagnostic approach.

    PubMed

    Nofal, Ahmad; Salah, Eman

    2013-09-01

    "Poikiloderma" is a morphologic and descriptive term referring to a combination of cutaneous atrophy, telangiectasia, and varied macular pigmentary changes that result in a mottled skin appearance. Its etiology includes both congenital and acquired causes. Many studies have reported different causes of acquired poikiloderma; however, no single well-defined classification has been explored to date. Herein, we analyze all the possible causes of acquired poikiloderma and propose an etiological classification that, hopefully, will lead to better characterization for this ill-defined condition. Moreover, this study presents a step-by-step approach to the management of patients with acquired poikiloderma and summarizes the key differentiating features for each individual cause, which may help in easy and precise diagnosis of different causes of acquired poikiloderma. PMID:22846690

  12. The Best Time to Acquire New Skills: Age-Related Differences in Implicit Sequence Learning across the Human Lifespan

    ERIC Educational Resources Information Center

    Janacsek, Karolina; Fiser, Jozsef; Nemeth, Dezso

    2012-01-01

    Implicit skill learning underlies obtaining not only motor, but also cognitive and social skills through the life of an individual. Yet, the ontogenetic changes in humans' implicit learning abilities have not yet been characterized, and, thus, their role in acquiring new knowledge efficiently during development is unknown. We investigated such…

  13. Usual and Virtual Reality Video Game-Based Physiotherapy for Children and Youth with Acquired Brain Injuries

    ERIC Educational Resources Information Center

    Levac, Danielle; Miller, Patricia; Missiuna, Cheryl

    2012-01-01

    Little is known about how therapists promote learning of functional motor skills for children with acquired brain injuries. This study explores physiotherapists' description of these interventions in comparison to virtual reality (VR) video game-based therapy. Six physiotherapists employed at a children's rehabilitation center participated in…

  14. Cdc42 controls the dilation of the exocytotic fusion pore by regulating membrane tension

    PubMed Central

    Bretou, Marine; Jouannot, Ouardane; Fanget, Isabelle; Pierobon, Paolo; Larochette, Nathanaël; Gestraud, Pierre; Guillon, Marc; Emiliani, Valentina; Gasman, Stéphane; Desnos, Claire; Lennon-Duménil, Ana-Maria; Darchen, François

    2014-01-01

    Membrane fusion underlies multiple processes, including exocytosis of hormones and neurotransmitters. Membrane fusion starts with the formation of a narrow fusion pore. Radial expansion of this pore completes the process and allows fast release of secretory compounds, but this step remains poorly understood. Here we show that inhibiting the expression of the small GTPase Cdc42 or preventing its activation with a dominant negative Cdc42 construct in human neuroendocrine cells impaired the release process by compromising fusion pore enlargement. Consequently the mode of vesicle exocytosis was shifted from full-collapse fusion to kiss-and-run. Remarkably, Cdc42-knockdown cells showed reduced membrane tension, and the artificial increase of membrane tension restored fusion pore enlargement. Moreover, inhibiting the motor protein myosin II by blebbistatin decreased membrane tension, as well as fusion pore dilation. We conclude that membrane tension is the driving force for fusion pore dilation and that Cdc42 is a key regulator of this force. PMID:25143404

  15. MOTOR BIKES, MOPEDS, AND MOTOR SCOOTERS Registration and Operation

    E-print Network

    Lozano-Robledo, Alvaro

    ://www.ct.gov/dot/LIB/dot/documents/dbikes/14-286.pdf Motorcycle - Motorcycle means a motor vehicle, with or without a side car, having not more and a motor which is not in the enclosed area. Motor Scooters - Many motor scooters are motorcycles and would require a registration and motorcycle operator's license to operate on the road. Some motor scooters fall

  16. Motor processes 1 Motor Processes in Mental Rotation1

    E-print Network

    Paris-Sud XI, Université de

    Motor processes 1 Motor Processes in Mental Rotation1 1 M.W. wishes to thank the LPPA for its on motor processes. First, motor rotation that is compatible with mental rotation results in faster times slow down or speed up the mental rotation. Cognition 68, 77-94 (1998) #12;Motor processes 2 Mental

  17. Potential disadvantages of using socially acquired information.

    PubMed Central

    Giraldeau, Luc-Alain; Valone, Thomas J; Templeton, Jennifer J

    2002-01-01

    The acquisition and use of socially acquired information is commonly assumed to be profitable. We challenge this assumption by exploring hypothetical scenarios where the use of such information either provides no benefit or can actually be costly. First, we show that the level of incompatibility between the acquisition of personal and socially acquired information will directly affect the extent to which the use of socially acquired information can be profitable. When these two sources of information cannot be acquired simultaneously, there may be no benefit to socially acquired information. Second, we assume that a solitary individual's behavioural decisions will be based on cues revealed by its own interactions with the environment. However, in many cases, for social animals the only socially acquired information available to individuals is the behavioural actions of others that expose their decisions, rather than the cues on which these decisions were based. We argue that in such a situation the use of socially acquired information can lead to informational cascades that sometimes result in sub-optimal behaviour. From this theory of informational cascades, we predict that when erroneous cascades are costly, individuals should pay attention only to socially generated cues and not behavioural decisions. We suggest three scenarios that might be examples of informational cascades in nature. PMID:12495513

  18. Sensor Fusion for the Detection of Landmines

    Microsoft Academic Search

    Martin Fritzsche; Otto Löhlein

    2000-01-01

    The detection of buried anti-personnel mines (APMs) is widely considered as a problem which may only be solved with a combination of two or more complementary sensors. We present processing and fusion results obtained from a multisensor data set, acquired with a pulse induction metal detector (MD), a pulsed ultra wide band ground penetrating radar (GPR) and a 3–5µ thermal

  19. Emergence of virtual reality as a tool for upper limb rehabilitation: incorporation of motor control and motor learning principles.

    PubMed

    Levin, Mindy F; Weiss, Patrice L; Keshner, Emily A

    2015-03-01

    The primary focus of rehabilitation for individuals with loss of upper limb movement as a result of acquired brain injury is the relearning of specific motor skills and daily tasks. This relearning is essential because the loss of upper limb movement often results in a reduced quality of life. Although rehabilitation strives to take advantage of neuroplastic processes during recovery, results of traditional approaches to upper limb rehabilitation have not entirely met this goal. In contrast, enriched training tasks, simulated with a wide range of low- to high-end virtual reality-based simulations, can be used to provide meaningful, repetitive practice together with salient feedback, thereby maximizing neuroplastic processes via motor learning and motor recovery. Such enriched virtual environments have the potential to optimize motor learning by manipulating practice conditions that explicitly engage motivational, cognitive, motor control, and sensory feedback-based learning mechanisms. The objectives of this article are to review motor control and motor learning principles, to discuss how they can be exploited by virtual reality training environments, and to provide evidence concerning current applications for upper limb motor recovery. The limitations of the current technologies with respect to their effectiveness and transfer of learning to daily life tasks also are discussed. PMID:25212522

  20. Acquired noncompaction in Duchenne muscular dystrophy.

    PubMed

    Finsterer, Josef; Stöllberger, Claudia; Gaismayer, Kurt; Janssen, Bart

    2006-01-26

    Acquired left ventricular hypertrabeculation/noncompaction (LVHT) is rare and has been described in patients with mitochondriopathy, Barth syndrome, and Becker muscular dystrophy. Here we report acquired LVHT in a 28-year-old man with Duchenne muscular dystrophy who required non-invasive, positive-pressure ventilation for muscular respiratory failure since age 16 years. Transthoracic echocardiography at age 22 years revealed enlarged left atrium and ventricle and reduced fractional shortening, but no LVHT. Transthoracic echocardiography at age 27 years revealed enlarged left atrium and ventricle, systolic dysfunction, mitral insufficiency, and, surprisingly, LVHT. The cause and pathomechanism of acquired LVHT in this patient remained speculative. PMID:16337060

  1. Fusion Science Education Outreach

    Microsoft Academic Search

    C. A. Danielson

    1996-01-01

    This presentation will focus on education outreach activities at General Atomics that have been expanded to include the general population on science education with a focus on fusion energy. Outreach materials are distributed upon request both nationally and internationally. These materials include a notebook containing copies of DIII--D tour panels, fusion poster, new fusion energy video, new fusion energy brochure,

  2. Traffic of Molecular Motors

    E-print Network

    Stefan Klumpp; Melanie J. I. Müller; Reinhard Lipowsky

    2005-12-06

    Molecular motors perform active movements along cytoskeletal filaments and drive the traffic of organelles and other cargo particles in cells. In contrast to the macroscopic traffic of cars, however, the traffic of molecular motors is characterized by a finite walking distance (or run length) after which a motor unbinds from the filament along which it moves. Unbound motors perform Brownian motion in the surrounding aqueous solution until they rebind to a filament. We use variants of driven lattice gas models to describe the interplay of their active movements, the unbound diffusion, and the binding/unbinding dynamics. If the motor concentration is large, motor-motor interactions become important and lead to a variety of cooperative traffic phenomena such as traffic jams on the filaments, boundary-induced phase transitions, and spontaneous symmetry breaking in systems with two species of motors. If the filament is surrounded by a large reservoir of motors, the jam length, i.e., the extension of the traffic jams is of the order of the walking distance. Much longer jams can be found in confined geometries such as tube-like compartments.

  3. Cryogenic Electric Motor Tested

    NASA Technical Reports Server (NTRS)

    Brown, Gerald V.

    2004-01-01

    Technology for pollution-free "electric flight" is being evaluated in a number of NASA Glenn Research Center programs. One approach is to drive propulsive fans or propellers with electric motors powered by fuel cells running on hydrogen. For large transport aircraft, conventional electric motors are far too heavy to be feasible. However, since hydrogen fuel would almost surely be carried as liquid, a propulsive electric motor could be cooled to near liquid hydrogen temperature (-423 F) by using the fuel for cooling before it goes to the fuel cells. Motor windings could be either superconducting or high purity normal copper or aluminum. The electrical resistance of pure metals can drop to 1/100th or less of their room-temperature resistance at liquid hydrogen temperature. In either case, super or normal, much higher current density is possible in motor windings. This leads to more compact motors that are projected to produce 20 hp/lb or more in large sizes, in comparison to on the order of 2 hp/lb for large conventional motors. High power density is the major goal. To support cryogenic motor development, we have designed and built in-house a small motor (7-in. outside diameter) for operation in liquid nitrogen.

  4. Motor nerve transplantation.

    PubMed

    Gray, W P; Keohane, C; Kirwan, W O

    1997-10-01

    The motor nerve transplantation (MNT) technique is used to transfer an intact nerve into a denervated muscle by harvesting a neurovascular pedicle of muscle containing motor endplates from the motor endplate zone of a donor muscle and implanting it into a denervated muscle. Thirty-six adult New Zealand White rabbits underwent reinnervation of the left long peroneal (LP) muscle (fast twitch) with a motor nerve graft from the soleus muscle (slow twitch). The right LP muscle served as a control. Reinnervation was assessed using microstimulatory single-fiber electromyography (SFEMG), alterations in muscle fiber typing and grouping, and isometric response curves. Neurofilament antibody was used for axon staining. The neurofilament studies provided direct evidence of nerve growth from the motor nerve graft into the adjacent denervated muscle. Median motor endplate jitter was 13 microsec preoperatively, and 26 microsec at 2 months, 29.5 microsec at 4 months, and 14 microsec at 6 months postoperatively (p < 0.001). Isometric tetanic tension studies showed a progressive functional recovery in the reinnervated muscle over 6 months. There was no histological evidence of aberrant reinnervation from any source outside the nerve pedicle. Isometric twitch responses and adenosine triphosphatase studies confirmed the conversion of the reinnervated LP muscle to a slow-type muscle. Acetylcholinesterase studies confirmed the presence of functioning motor endplates beneath the insertion of the motor nerve graft. It is concluded that the MNT technique achieves motor reinnervation by growth of new nerve fibers across the pedicle graft into the recipient muscle. PMID:9322851

  5. Hybrid vehicle motor alignment

    DOEpatents

    Levin, Michael Benjamin (Ann Arbor, MI)

    2001-07-03

    A rotor of an electric motor for a motor vehicle is aligned to an axis of rotation for a crankshaft of an internal combustion engine having an internal combustion engine and an electric motor. A locator is provided on the crankshaft, a piloting tool is located radially by the first locator to the crankshaft. A stator of the electric motor is aligned to a second locator provided on the piloting tool. The stator is secured to the engine block. The rotor is aligned to the crankshaft and secured thereto.

  6. Trajectories of Happiness Following Acquired Disability 

    E-print Network

    McCord, Carly Elizabeth

    2013-07-09

    Current deficits in the rehabilitation psychology literature involving longitudinal studies investigating positive outcomes following acquired disabilities have deserved research attention. In the current study, data on happiness as an enduring...

  7. Towards an Operational Sensor-Fusion System for Anti-Personnel Landmine Detection

    Microsoft Academic Search

    Frank Cremer; Klamer Schutte; John G. m. Schavemaker; Eric Den Breejen

    2000-01-01

    To acquire detection performance required for an operational system for the detection of anti-personnel landmines, it is necessaryto use multiple sensors and sensor-fusion techniques. This paper describes five decision-level sensor-fusion techniquesand their common optimisation method.

  8. Ontario Hydro Motor Efficiency Study 

    E-print Network

    Dautovich, D. R.

    1980-01-01

    "high efficiency" motor is described and the operating cost is compared to the standard motor. Payback for high efficiency motors is found to be about one year for continuous duty applications. Specific instructions are presented for use in industry....

  9. Ontario Hydro Motor Efficiency Study

    E-print Network

    Dautovich, D. R.

    1980-01-01

    Electric motors consume more than one-half of the electrical energy produced by Ontario Hydro. In the residential sector, the major motor load is for refrigerators and freezers while packaged equipment dominate the motor load in the commercial...

  10. The Basal Ganglia and Adaptive Motor Control

    NASA Astrophysics Data System (ADS)

    Graybiel, Ann M.; Aosaki, Toshihiko; Flaherty, Alice W.; Kimura, Minoru

    1994-09-01

    The basal ganglia are neural structures within the motor and cognitive control circuits in the mammalian forebrain and are interconnected with the neocortex by multiple loops. Dysfunction in these parallel loops caused by damage to the striatum results in major defects in voluntary movement, exemplified in Parkinson's disease and Huntington's disease. These parallel loops have a distributed modular architecture resembling local expert architectures of computational learning models. During sensorimotor learning, such distributed networks may be coordinated by widely spaced striatal interneurons that acquire response properties on the basis of experienced reward.

  11. Stripped-down Motor

    NSDL National Science Digital Library

    The Exploratorium

    2007-01-01

    In this activity, you'll make an electric motor--a simple version of the electric motors found in toys, tools, and appliances everywhere. The activity includes three short online videos: Introduction, Step-by-Step Instructions, and What's Going On. Also available: a concept map and a "Going Further" document that suggests variations on this activity.

  12. Sensorless, Online Motor Diagnostics

    E-print Network

    Yazici, Birsen

    , a set of techniques has been developed for diagnosing motor problems before they reach the point are large enough, various temperature sensors, accelerometers, and even flux sensors have been added is particularly attractive, as the current (and voltage) sensors are usually installed in the motor control center

  13. Stepping motor controller

    DOEpatents

    Bourret, Steven C. (Los Alamos, NM); Swansen, James E. (Los Alamos, NM)

    1984-01-01

    A stepping motor is microprocessingly controlled by digital circuitry which monitors the output of a shaft encoder adjustably secured to the stepping motor and generates a subsequent stepping pulse only after the preceding step has occurred and a fixed delay has expired. The fixed delay is variable on a real-time basis to provide for smooth and controlled deceleration.

  14. Advanced solid rocket motor

    NASA Technical Reports Server (NTRS)

    Jones, Kenneth W.; Zoller, Lowell K.

    1989-01-01

    The Advanced Solid Rocket Motor (ASRM), a 150-in diameter segmented motor design that incorporates substantive design changes to improve the reliability and design safety margins of the Space Shuttle system, is discussed. The studies involved in the development of the ASRM are reviewed, and the ASRM design is summarized, including safety enhancement and performance improvement features. The ASRM program plan is briefly addressed.

  15. Bemerkungen zur "kalten Fusion"

    E-print Network

    Kuehne, R W

    2006-01-01

    Steven Jones et al. reported to have observed nuclear fusion at room temperature. They observed this "cold fusion" by electrolyzing heavy water. Later experiments confirmed these observations. These experiments confirmed the generation of strong electric fields within the deuterided metals. These electric fields accelerate the deuterons to keV energies and allow the observed nuclear fusion. Roman Sioda and I suggested a theoretical description of this nuclear fusion. Our "extended micro hot fusion" scenario explains how nuclear fusion can be generated over a long time within deuterided metals. Moreover we predicted the explosion of large pieces of deuterided metals. This article reviews the "cold fusion" work of Steven Jones et al. and discusses the fracto-fusion scenario. I show that the extended micro hot fusion scenario can explain the observed neutron emissions, neutron bursts, and heat bursts.

  16. Fusion energy

    SciTech Connect

    Not Available

    1990-09-01

    The main purpose of the International Thermonuclear Experimental Reactor (ITER) is to develop an experimental fusion reactor through the united efforts of many technologically advanced countries. The ITER terms of reference, issued jointly by the European Community, Japan, the USSR, and the United States, call for an integrated international design activity and constitute the basis of current activities. Joint work on ITER is carried out under the auspices of the International Atomic Energy Agency (IAEA), according to the terms of quadripartite agreement reached between the European Community, Japan, the USSR, and the United States. The site for joint technical work sessions is at the MaxPlanck Institute of Plasma Physics. Garching, Federal Republic of Germany. The ITER activities have two phases: a definition phase performed in 1988 and the present design phase (1989--1990). During the definition phase, a set of ITER technical characteristics and supporting research and development (R D) activities were developed and reported. The present conceptual design phase of ITER lasts until the end of 1990. The objectives of this phase are to develop the design of ITER, perform a safety and environmental analysis, develop site requirements, define future R D needs, and estimate cost, manpower, and schedule for construction and operation. A final report will be submitted at the end of 1990. This paper summarizes progress in the ITER program during the 1989 design phase.

  17. Cold fusion

    SciTech Connect

    Bush, R.T. (California State Polytechnic Univ., Physics Dept., Pomona, CA (US))

    1991-03-01

    The transmission resonance model (TRM) is combined with some electrochemistry of the cathode surface and found to provide a good fit to new data on excess heat. For the first time, a model for cold fusion not only fits calorimetric data but also predicts optimal trigger points. This suggests that the model is meaningful and that the excess heat phenomenon claimed by Fleischmann and Pons is genuine. A crucial role is suggested for the overpotential and, in particular, for the concentration overpotential, i.e., the hydrogen overvoltage. Self-similar geometry, or scale invariance, i.e., a fractal nature, is revealed by the relative excess power function. Heat bursts are predicted with a scale invariance in time, suggesting a possible link between the TRM and chaos theory. The model describes a near-surface phenomenon with an estimated excess power yield of {approximately}1 kW/cm{sup 3} Pd, as compared to 50 W/cm{sup 3} of reactor core for a good fission reactor. Transmission resonance-induced nuclear transmutation, a new type of nuclear reaction, is strongly suggested with two types emphasized: transmission resonance-induced neutron transfer reactions yielding essentially the same end result as Teller's hypothesized catalytic neutron transfer and a three-body reaction promoted by standing de Broglie waves. In this paper suggestions for the anomalous production of heat, particles, and radiation are given.

  18. Fusion energy

    NASA Astrophysics Data System (ADS)

    1990-09-01

    The main purpose of the International Thermonuclear Experimental Reactor (ITER) is to develop an experimental fusion reactor through the united efforts of many technologically advanced countries. The ITER terms of reference, issued jointly by the European Community, Japan, the USSR, and the United States, call for an integrated international design activity and constitute the basis of current activities. Joint work on ITER is carried out under the auspices of the International Atomic Energy Agency (IAEA), according to the terms of quadripartite agreement reached between the European Community, Japan, the USSR, and the United States. The site for joint technical work sessions is at the Max Planck Institute of Plasma Physics. Garching, Federal Republic of Germany. The ITER activities have two phases: a definition phase performed in 1988 and the present design phase (1989 to 1990). During the definition phase, a set of ITER technical characteristics and supporting research and development (R and D) activities were developed and reported. The present conceptual design phase of ITER lasts until the end of 1990. The objectives of this phase are to develop the design of ITER, perform a safety and environmental analysis, develop site requirements, define future R and D needs, and estimate cost, manpower, and schedule for construction and operation. A final report will be submitted at the end of 1990. This paper summarizes progress in the ITER program during the 1989 design phase.

  19. Review of fusion synfuels

    SciTech Connect

    Fillo, J.A.

    1980-01-01

    Thermonuclear fusion offers an inexhaustible source of energy for the production of hydrogen from water. Depending on design, electric generation efficiencies of approx. 40 to 60% and hydrogen production efficiencies by high-temperature electrolysis of approx. 50 to 65% are projected for fusion reactors using high-temperatures blankets. Fusion/coal symbiotic systems appear economically promising for the first generation of commercial fusion synfuels plants. Coal production requirements and the environmental effects of large-scale coal usage would be greatly reduced by a fusion/coal system. In the long term, there could be a gradual transition to an inexhaustible energy system based solely on fusion.

  20. System and method for motor parameter estimation

    SciTech Connect

    Luhrs, Bin; Yan, Ting

    2014-03-18

    A system and method for determining unknown values of certain motor parameters includes a motor input device connectable to an electric motor having associated therewith values for known motor parameters and an unknown value of at least one motor parameter. The motor input device includes a processing unit that receives a first input from the electric motor comprising values for the known motor parameters for the electric motor and receive a second input comprising motor data on a plurality of reference motors, including values for motor parameters corresponding to the known motor parameters of the electric motor and values for motor parameters corresponding to the at least one unknown motor parameter value of the electric motor. The processor determines the unknown value of the at least one motor parameter from the first input and the second input and determines a motor management strategy for the electric motor based thereon.

  1. Fusion Power Associates, 2011 Annual Meeting 1 General Fusion

    E-print Network

    Fusion Power Associates, 2011 Annual Meeting 1 General Fusion #12;Fusion Power Associates, 2011 Annual Meeting 2 General Fusion Making commercially viable fusion power a reality. · Founded in 2002, based in Vancouver, Canada · Plan to demonstrate a fusion system capable of "net gain" within 3 years

  2. Fusion Power Associates, 2012 Annual Meeting 1 General Fusion

    E-print Network

    Fusion Power Associates, 2012 Annual Meeting 1 General Fusion #12;Fusion Power Associates, 2012 Annual Meeting 2 General Fusion Making affordable fusion power a reality. · Founded in 2002, based to demonstrate the first fusion system capable of "net gain" 3 years after proof · Validated by leading experts

  3. FUSION NUCLEAR SCIENCE PROGRAM & SUPPORTING FUSION NUCLEAR SCIENCE FACILITY (FNSF)

    E-print Network

    irradiation effects on materials Harnessing Fusion Power · Fusion power extraction and tritium breedingFUSION NUCLEAR SCIENCE PROGRAM & SUPPORTING FUSION NUCLEAR SCIENCE FACILITY (FNSF): UPDATE and plasma contamination are required. 4. Harnessing Fusion Power Fusion energy from deuterium-tritium (D

  4. Pixel saliency metric based pixel-level medical image fusion

    Microsoft Academic Search

    Hang Tan; Xianhe Huang; HuaChun Tan

    2011-01-01

    This paper proposes a novel medical image fusion algorithm based on pixel salience metric in gradient domain. We first obtain the gradient image of every input image and measure their salience map, and then use saliency to weight gradient pixel to acquire a target gradient field. Applying dynamic range compression (DRC) algorithm to reduce halo effect. Finally, exploiting successive over-relaxation

  5. Motor-pump aggregate

    SciTech Connect

    Schneider, W.; Gaffal, K.; Peters, J.

    1983-10-04

    A motor-pump aggregate whose pump is a glandless centrifugal pump and is intended for use in a nuclear reactor plant has hollow coaxial pump and motor shafts which are sealingly coupled to each other. To this end, the first end portion of the pump shaft extends into the adjacent first end portion of the motor shaft and has an external conical shoulder for engagement with an internal conical seat of the first end portion of the motor shaft. A feather holds the first end portions against rotation relative to one another, and the shoulder is urged against the seat by a pair of threaded connectors one of which is anchored in a disc-shaped member in the region of the second end portion of the motor shaft and the other of which is anchored in the first end portion of the pump shaft. The disc-shaped member and the second end portion of the motor shaft have mating ring gears to ensure accurate and a reproducible centering. The connection between the second end portion of the pump shaft and an impeller is similar to that between the second end portion of the motor shaft and the disc-shaped member except that one of the respective connectors is anchored in a transverse end wall which is inserted into the second end portion of and is welded to the pump shaft.

  6. Magnetic resonance imaging of acquired cardiac disease.

    PubMed Central

    Carrol, C L; Higgins, C B; Caputo, G R

    1996-01-01

    Over the last 15 years, advances in magnetic resonance imaging techniques have increased the accuracy and applicability of cardiovascular magnetic resonance imaging. These advances have improved the utility of magnetic resonance imaging in evaluating cardiac morphology, blood flow, and myocardial contractility, all significant diagnostic features in the evaluation of the patient with acquired heart disease. Utilization of cardiovascular magnetic resonance imaging has been limited, primarily due to clinical reliance upon nuclear scintigraphy and echocardiography. Recent developments in fast and ultrafast imaging should continue to enhance the significance of magnetic resonance imaging in this field. Widespread use of magnetic resonance imaging in the evaluation of the cardiovascular system will ultimately depend upon its maturation into a comprehensive, noninvasive imaging technique for the varying manifestations of acquired heart disease, including cardiomyopathy, ischemic heart disease, and acquired valvular disease. Images PMID:8792545

  7. Citizenship and autonomy in acquired brain injury.

    PubMed

    Schipper, Karen; Widdershoven, Guy A M; Abma, Tineke A

    2011-07-01

    In ethical theory, different concepts of autonomy can be distinguished. In this article we explore how these concepts of autonomy are combined in theory in the citizenship paradigm, and how this turns out in the practice of care for people with acquired brain injury. The stories of a professional caregiver and a client with acquired brain injury show that the combination of various concepts of autonomy in practice leads to tensions between caregivers and clients. These dynamics are discussed from a care ethics perspective, stressing the importance of relationships and interdependence, as well as paying attention to various, sometimes conflicting, perspectives in a deliberative dialogue. PMID:21788288

  8. Towards a microrotary motor driven by motor proteins

    Microsoft Academic Search

    Yuichi Hiratsuka; Shoji Takeuchi

    2007-01-01

    Biological molecular motors, motor proteins, have a number of unique advantages over artificial motors, including efficient conversion of chemical energy into mechanical work and the potential for self-assembly into larger structures. This paper describes a bio- hybrid micro rotary motor using kinesin\\/ microtubule motor. We developed a simple fabrication process for a micro-structure by one-time deposition of parylene and a

  9. ChemTeacher: Fusion

    NSDL National Science Digital Library

    2011-01-01

    ChemTeacher compiles background information, videos, articles, demonstrations, worksheets and activities for high school teachers to use in their classrooms. The Fusion page includes resources for teaching students about the discovery and applications of fusion.

  10. Fusion Energy Sciences Program Mission

    E-print Network

    Fusion Energy Sciences Program Mission The Fusion Energy Sciences (FES) program leads the national research effort to advance plasma science, fusion science, and fusion technology--the knowledge base needed for an economically and environmentally attractive fusion energy source. The National Energy Policy states that fusion

  11. Justification for Energy Efficient Motors 

    E-print Network

    Buschart, R. J.

    1981-01-01

    This paper presents the results of a study of Energy Efficient (or EE) motors in NEMA frame sizes, (1-200 HP). It examines the economics of using EE motors for new motor requirements, as replacements for motors - instead of rewinding...

  12. Markov Process of Muscle Motors

    E-print Network

    Yu. Kondratiev; E. Pechersky; S. Pirogov

    2007-06-20

    We study a Markov random process describing a muscle molecular motor behavior. Every motor is either bound up with a thin filament or unbound. In the bound state the motor creates a force proportional to its displacement from the neutral position. In both states the motor spend an exponential time depending on the state. The thin filament moves at its velocity proportional to average of all displacements of all motors. We assume that the time which a motor stays at the bound state does not depend on its displacement. Then one can find an exact solution of a non-linear equation appearing in the limit of infinite number of the motors.

  13. Stepper Motors Tutorials

    NSDL National Science Digital Library

    This resource presents tutorials about stepper motors. Topics include unipolar, bipolar, current control, and micro stepping. Clicking on each topic provides an in-depth tutorial complete with graphics.

  14. Piezoelectric Rotary Tube Motor

    NASA Technical Reports Server (NTRS)

    Fisher, Charles D.; Badescu, Mircea; Braun, David F.; Culhane, Robert

    2011-01-01

    A custom rotary SQUIGGLE(Registered TradeMark) motor has been developed that sets new benchmarks for small motor size, high position resolution, and high torque without gear reduction. Its capabilities cannot be achieved with conventional electromagnetic motors. It consists of piezoelectric plates mounted on a square flexible tube. The plates are actuated via voltage waveforms 90 out of phase at the resonant frequency of the device to create rotary motion. The motors were incorporated into a two-axis postioner that was designed for fiber-fed spectroscopy for ground-based and space-based projects. The positioner enables large-scale celestial object surveys to take place in a practical amount of time.

  15. MotorWeek

    SciTech Connect

    None

    2009-01-01

    In 2008, PBS's MotorWeek, television's original automotive magazine, visited Argonne's Transportation Technology R&D Center "to learn what it really takes to make clean power sources a viable reality."

  16. Energy Efficient Motors 

    E-print Network

    Hoffmeyer, W.

    1982-01-01

    Efficiency is only one aspect of motor performance. This paper discusses how efficiency is influenced by such factors as horsepower rating, poles, actual load, and starting requirements. It discusses some of the variables affecting efficiency...

  17. MotorWeek

    ScienceCinema

    None

    2013-04-19

    In 2008, PBS's MotorWeek, television's original automotive magazine, visited Argonne's Transportation Technology R&D Center "to learn what it really takes to make clean power sources a viable reality."

  18. Linear Motor Powered Transportation

    E-print Network

    Thornton, Richard D.

    This special issue on linear-motor powered transportation covers both supporting technologies and innovative transport systems in various parts of the World, as this technology moves from the lab to commercial operations. ...

  19. Dielectric fluid motors

    SciTech Connect

    Otsubo, Y. [Center of Cooperative Research, Chiba University, Yayoi-cho 1-33, Inage-ku, Chiba-shi 263 (Japan)] [Center of Cooperative Research, Chiba University, Yayoi-cho 1-33, Inage-ku, Chiba-shi 263 (Japan); Edamura, K. [New Technology Management Co., Higashi-Shinkoiwa 2-9-1-306, Katsushika-ku, Tokyo 124 (Japan)] [New Technology Management Co., Higashi-Shinkoiwa 2-9-1-306, Katsushika-ku, Tokyo 124 (Japan)

    1997-07-01

    On the application of high electric fields to a dielectric fluid, a convective motion of the fluid is induced. By controlling the fluid motion in nonuniform dc fields, a new type of fluid motor is developed. An angular velocity of more than 15s{sup {minus}1} (150 rpm) can be achieved at a dc voltage of 5 kV for a motor with a rotor radius of 10 mm. The efficiency of energy transformation from electric to kinetic energy is about 4{percent}. Since magnetic fields and switching circuits are not required, the advantage of the fluid motor will be enhanced by size reduction. The dielectric fluid motor is attractive as a source of mechanical energy in a micromachine. {copyright} {ital 1997 American Institute of Physics.}

  20. Acquired alexia with agraphia syndrome in childhood.

    PubMed

    Paquier, Philippe F; De Smet, Hyo Jung; Mariën, Peter; Poznanski, Nathalie; Van Bogaert, Patrick

    2006-04-01

    The acquired alexia with agraphia syndrome is a conspicuous disorder of reading and writing in the absence of significant other language impairments that has mainly been recorded in adults. Pure cases are rare, with most patients displaying mild aphasic deficits. In children, acquired reading and writing disorders are generally reported as part of more encompassing aphasic syndromes affecting oral and written language equally, for example, Broca or Wernicke aphasia. Documented instances of predominant acquired reading and writing disorders in childhood are exceptional. We report an 11-year-old, right-handed boy who sustained a left temporoparieto-occipital hematoma following rupture of an arteriovenous malformation and who consecutively presented with the acquired alexia with agraphia syndrome associated with word-finding difficulties. Neuropsychologic and neurolinguistic data showed that there was no concomitant Gerstmann and/or angular gyrus syndrome. Th e recoveryfrom the anomia was quite favorable, but recovery of written language was more protracted and acted on the patient's further scholastic achievement. This case is reminiscent of a historical childhood case reported in 1939 and is consonant with adult cases in terms of lesion location and semiologic picture. PMID:16900930

  1. Support Network Responses to Acquired Brain Injury

    ERIC Educational Resources Information Center

    Chleboun, Steffany; Hux, Karen

    2011-01-01

    Acquired brain injury (ABI) affects social relationships; however, the ways social and support networks change and evolve as a result of brain injury is not well understood. This study explored ways in which survivors of ABI and members of their support networks perceive relationship changes as recovery extends into the long-term stage. Two…

  2. Neural Correlates of Acquired Color Category Effects

    ERIC Educational Resources Information Center

    Clifford, Alexandra; Franklin, Anna; Holmes, Amanda; Drivonikou, Vicky G.; Ozgen, Emre; Davies, Ian R. L.

    2012-01-01

    Category training can induce category effects, whereby color discrimination of stimuli spanning a newly learned category boundary is enhanced relative to equivalently spaced stimuli from within the newly learned category (e.g., categorical perception). However, the underlying mechanisms of these acquired category effects are not fully understood.…

  3. How Did Light Acquire a Velocity?

    ERIC Educational Resources Information Center

    Lauginie, Pierre

    2013-01-01

    We discuss how light acquired a velocity through history, from the ancient Greeks to the early modern era. Combining abstract debates, models of light, practical needs, planned research and chance, this history illustrates several key points that should be brought out in science education.

  4. Acquired double pylorus: a case report.

    PubMed

    Chen, Qing-Yu; Chen, Yan; Liang; Wang, Jing; Du, Qin; Cai, Jian-Ting; Chen, Jia-Min

    2012-06-01

    Double pylorus is one of the rare anomalies of the gastrointestinal tract, it can be congenital or acquired. In this case we report a case of double pylorus because of chronic peptic ulcer. Upper GI endoscopy revealed gastroduodenal fistula located on the lesser curve of the antrum, the patient's symptoms were improved rapidly by intensive antiulcer treatment. PMID:22575987

  5. A Systematic Method for Acquiring Regulatory Requirements

    E-print Network

    Breaux, Travis D.

    Challenges to Compliance Acquiring Regulatory Requirements Ambiguity Traceability The Frame-Based Req (FAA, FCC, FDA, HHS, etc.) develop regulations Industry creates standards that support regulations Industry and government perform regulatory audits U.S. Federal courts decide: (1) industry compliance

  6. Treatment of Community-Acquired Pneumonia

    Microsoft Academic Search

    John Bartlett

    2000-01-01

    Lower respiratory tract infections are the major cause of death due to infectious disease in the developed and developing world. Despite substantial progress in defining pathogens and in therapeutic options, there continues to be major controversies in the clinical management of these infections. This report reviews the guidelines for community-acquired pneumonia from the Infectious Diseases Society of America (IDSA), updated

  7. SIGGRAPH 2002 Course 39 Acquiring Material Models

    E-print Network

    O'Brien, James F.

    , including recent Siggraph courses, on active and passive 3D photography to acquire object geometry from real geometry is known using 3D photography methods. Nevertheless, we seek to solve an inverse problem. Our with complex BRDFs [Lensch] Modeling and synthesizing 3D textures [Yu] Image-based measurement of translucent

  8. Chronic Acquired Demyelinating Polyneuropathy following Renal Transplantation

    PubMed Central

    Younger, D. S.; Orsher, Stuart

    2013-01-01

    The clinical, laboratory, and treatment findings of a patient with chronic acquired demyelinating polyneuropathy (CADP) in association with renal transplantation are described. Like the present case, many such patients have been described under the rubric of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). PMID:24363943

  9. Acquiring Financial Management Software: A Prototyping Approach.

    ERIC Educational Resources Information Center

    Wilson, John H.

    1990-01-01

    When the Smithsonian Institution recently acquired a new financial management system, the concept of prototyping was used throughout the process, but in a broader sense than in software development. It was used to refine requirements, establish software management techniques, test a logistical system, and implement and apply the package. (MSE)

  10. Slow liner fusion

    SciTech Connect

    Shaffer, M.J.

    1997-08-01

    {open_quotes}Slow{close_quotes} liner fusion ({approximately}10 ms compression time) implosions are nondestructive and make repetitive ({approximately} 1 Hz) pulsed liner fusion reactors possible. This paper summarizes a General Atomics physics-based fusion reactor study that showed slow liner feasibility, even with conservative open-line axial magnetic field confinement and Bohm radial transport.

  11. Motor adaptation and generalization of reaching movements using motor primitives based on spatial coordinates.

    PubMed

    Tanaka, Hirokazu; Sejnowski, Terrence J

    2015-02-15

    The brain processes sensory and motor information in a wide range of coordinate systems, ranging from retinal coordinates in vision to body-centered coordinates in areas that control musculature. Here we focus on the coordinate system used in the motor cortex to guide actions and examine physiological and psychophysical evidence for an allocentric reference frame based on spatial coordinates. When the equations of motion governing reaching dynamics are expressed as spatial vectors, each term is a vector cross product between a limb-segment position and a velocity or acceleration. We extend this computational framework to motor adaptation, in which the cross-product terms form adaptive bases for canceling imposed perturbations. Coefficients of the velocity- and acceleration-dependent cross products are assumed to undergo plastic changes to compensate the force-field or visuomotor perturbations. Consistent with experimental findings, each of the cross products had a distinct reference frame, which predicted how an acquired remapping generalized to untrained location in the workspace. In response to force field or visual rotation, mainly the coefficients of the velocity- or acceleration-dependent cross products adapted, leading to transfer in an intrinsic or extrinsic reference frame, respectively. The model further predicted that remapping of visuomotor rotation should under- or overgeneralize in a distal or proximal workspace. The cross-product bases can explain the distinct patterns of generalization in visuomotor and force-field adaptation in a unified way, showing that kinematic and dynamic motor adaptation need not arise through separate neural substrates. PMID:25429111

  12. Utilizing ZFS for the Storage of Acquired Data

    SciTech Connect

    C. Pugh, P. Henderson, K. Silber, T. Carroll, K. Ying

    2009-02-04

    Every day, the amount of data that is acquired from plasma experiments grows dramatically. It has become difficult for systems administrators to keep up with the growing demand for hard drive storage space. In the past, project storage has been supplied using UNIX filesystem (ufs) partitions. In order to increase the size of the disks using this system, users were required to discontinue use of the disk, so the existing data could be transferred to a disk of larger capacity or begin use of a completely new and separate disk, thus creating a segmentation of data storage. With the application of ZFS pools, the data capacity woes are over. ZFS provides simple administration that eliminates the need to unmount to resize, or transfer data to a larger disk. With a storage limit of 16 Exabytes (1018), ZFS provides immense scalability. Utilizing ZFS as the new project disk file system, users and administrators can eliminate time wasted waiting for data to transfer from one hard drive to another, and also enables more efficient use of disk space, as system administrators need only allocate what is presently required. This paper will discuss the application and benefits of using ZFS as an alternative to traditional data access and storage in the fusion environment.

  13. A New Type of Motor: Pneumatic Step Motor.

    PubMed

    Stoianovici, Dan; Patriciu, Alexandru; Petrisor, Doru; Mazilu, Dumitru; Kavoussi, Louis

    2007-02-01

    This paper presents a new type of pneumatic motor, a pneumatic step motor (PneuStep). Directional rotary motion of discrete displacement is achieved by sequentially pressurizing the three ports of the motor. Pulsed pressure waves are generated by a remote pneumatic distributor. The motor assembly includes a motor, gearhead, and incremental position encoder in a compact, central bore construction. A special electronic driver is used to control the new motor with electric stepper indexers and standard motion control cards. The motor accepts open-loop step operation as well as closed-loop control with position feedback from the enclosed sensor. A special control feature is implemented to adapt classic control algorithms to the new motor, and is experimentally validated. The speed performance of the motor degrades with the length of the pneumatic hoses between the distributor and motor. Experimental results are presented to reveal this behavior and set the expectation level. Nevertheless, the stepper achieves easily controllable precise motion unlike other pneumatic motors. The motor was designed to be compatible with magnetic resonance medical imaging equipment, for actuating an image-guided intervention robot, for medical applications. For this reason, the motors were entirely made of nonmagnetic and dielectric materials such as plastics, ceramics, and rubbers. Encoding was performed with fiber optics, so that the motors are electricity free, exclusively using pressure and light. PneuStep is readily applicable to other pneumatic or hydraulic precision-motion applications. PMID:21528106

  14. A New Type of Motor: Pneumatic Step Motor

    PubMed Central

    Stoianovici, Dan; Patriciu, Alexandru; Petrisor, Doru; Mazilu, Dumitru; Kavoussi, Louis

    2011-01-01

    This paper presents a new type of pneumatic motor, a pneumatic step motor (PneuStep). Directional rotary motion of discrete displacement is achieved by sequentially pressurizing the three ports of the motor. Pulsed pressure waves are generated by a remote pneumatic distributor. The motor assembly includes a motor, gearhead, and incremental position encoder in a compact, central bore construction. A special electronic driver is used to control the new motor with electric stepper indexers and standard motion control cards. The motor accepts open-loop step operation as well as closed-loop control with position feedback from the enclosed sensor. A special control feature is implemented to adapt classic control algorithms to the new motor, and is experimentally validated. The speed performance of the motor degrades with the length of the pneumatic hoses between the distributor and motor. Experimental results are presented to reveal this behavior and set the expectation level. Nevertheless, the stepper achieves easily controllable precise motion unlike other pneumatic motors. The motor was designed to be compatible with magnetic resonance medical imaging equipment, for actuating an image-guided intervention robot, for medical applications. For this reason, the motors were entirely made of nonmagnetic and dielectric materials such as plastics, ceramics, and rubbers. Encoding was performed with fiber optics, so that the motors are electricity free, exclusively using pressure and light. PneuStep is readily applicable to other pneumatic or hydraulic precision-motion applications. PMID:21528106

  15. Reduced procedural motor learning in deaf individuals

    PubMed Central

    Lévesque, Justine; Théoret, Hugo; Champoux, François

    2014-01-01

    Studies in the deaf suggest that cross-modal neuroplastic changes may vary across modalities. Only a handful of studies have examined motor capacities in the profoundly deaf. These studies suggest the presence of deficits in manual dexterity and delays in movement production. As of yet, the ability to learn complex sequential motor patterns has not been explored in deaf populations. The aim of the present study was to investigate the procedural learning skills of deaf adults. A serial reaction-time task (SRTT) was performed by 18 deaf subjects and 18 matched controls to investigate possible motor alteration subsequent to auditory deprivation. Deaf participants had various degrees of hearing loss. Half of the experimental group were early deaf adults mostly using hearing aids, the remaining half were late-deaf adults using a cochlear implant (CI). Participants carried out a repeating 12-item sequence of key presses along with random blocks containing no repeating sequence. Non-specific and sequence-specific learning was analyzed in relation to individual features related to the hearing loss. The results revealed significant differences between groups in sequence-specific learning, with deaf subjects being less efficient than controls in acquiring sequence-specific knowledge. We interpret the results in light of cross-modal plasticity and the auditory scaffolding hypothesis. PMID:24904381

  16. Magnetized target fusion and fusion propulsion.

    SciTech Connect

    Kirkpatrick, R. C. (Ronald C.)

    2001-01-01

    Magnetized target fusion (MTF) is a thermonuclear fusion concept that is intermediate between the two mainline approaches, magnetic confinement and inertial confinement fusion (MCF and ICF). MTF incorporates some aspects of each and offers advantages over each of the mainline approaches. First, it provides a means of reducing the driver power requirements, thereby admitting a wider range of drivers than ICF. Second, the magnetic field is only used for insulation, not confinement, and the plasma is wall confined, so that plasma instabilities are traded in for hydrodynamic instabilities. However, the degree of compression required to reach fusion conditions is lower than for ICF, so that hydrodynamic instabilities are much less threatening. The standoff driver innovation proposes to dynamically form the target plasma and a gaseous shell that compresses and confines the target plasma. Therefore, fusion target fabrication is traded in for a multiplicity of plasma guns, which must work in synchrony. The standoff driver embodiment of MTF leads to a fusion propulsion system concept that is potentially compact and lightweight. We will discuss the underlying physics of MTF and some of the details of the fusion propulsion concept using the standoff driver approach. We discuss here the optimization of an MTF target design for space propulsion.

  17. Multifocal Motor Neuropathy: Update on Clinical Characteristics, Pathophysiological Concepts and Therapeutic Options

    Microsoft Academic Search

    Sven G. Meuth; Christoph Kleinschnitz

    2010-01-01

    Multifocal motor neuropathy (MMN) is an acquired immune-mediated neuropathy characterized by chronic or stepwise progressive asymmetrical limb weakness without sensory deficits. The upper extremities are more often affected than the lower extremities with distal paresis dominating over proximal paresis. Important diagnostic features are persistent multifocal partial conduction blocks (CBs) and the presence of high-titer anti-GM1 serum antibodies. Motor neuron disease,

  18. The fusion breeder

    NASA Astrophysics Data System (ADS)

    Moir, Ralph W.

    1982-10-01

    The fusion breeder is a fusion reactor designed with special blankets to maximize the transmutation by 14 MeV neutrons of uranium-238 to plutonium or thorium to uranium-233 for use as a fuel for fission reactors. Breeding fissile fuels has not been a goal of the U.S. fusion energy program. This paper suggests it is time for a policy change to make the fusion breeder a goal of the U.S. fusion program and the U.S. nuclear energy program. There is wide agreement that many approaches will work and will produce fuel for five equal-sized LWRs, and some approach as many as 20 LWRs at electricity costs within 20% of those at today's price of uranium (30/lb of U3O8). The blankets designed to suppress fissioning, called symbiotes, fusion fuel factories, or just fusion breeders, will have safety characteristics more like pure fusion reactors and will support as many as 15 equal power LWRs. The blankets designed to maximize fast fission of fertile material will have safety characteristics more like fission reactors and will support 5 LWRs. This author strongly recommends development of the fission suppressed blanket type, a point of view not agreed upon by everyone. There is, however, wide agreement that, to meet the market price for uranium which would result in LWR electricity within 20% of today's cost with either blanket type, fusion components can cost severalfold more than would be allowed for pure fusion to meet the goal of making electricity alone at 20% over today's fission costs. Also widely agreed is that the critical-path-item for the fusion breeder is fusion development itself; however, development of fusion breeder specific items (blankets, fuel cycle) should be started now in order to have the fusion breeder by the time the rise in uranium prices forces other more costly choices.

  19. Acquired undescended testis: putting the pieces together.

    PubMed

    Hack, W W M; Goede, J; van der Voort-Doedens, L M; Meijer, R W

    2012-02-01

    Acquired undescended testis is now a well-recognized disorder. It is seen in 1.5% of pre-pubertal boys and accounts for the 1-2% orchidopexy rate in older boys. Its pathogenesis remains largely unclear, but it may be caused by a fibrous remnant of the processus vaginalis. There is much controversy over its management, and the proper management awaits a randomized-controlled trial. Until now, follow-up data are available only for cases of spontaneous descent or pubertal orchidopexy. It is speculated that acquired undescended testis is in fact congenital and because of a short funiculus at birth, allowing a low-scrotal position early in life. However, as the boy grows, the testis might evolve into an undescended state. When testosterone surges at puberty, spontaneous descent occurs in three of every four cases. PMID:21651571

  20. Egocentric Representation Acquired from Offline Map Learning

    PubMed Central

    Xiao, Chengli; Zhang, Lei

    2013-01-01

    It is widely accepted that people establish allocentric spatial representation after learning a map. However, it is unknown whether people can directly acquire egocentric representation after map learning. In two experiments, the participants learned a distal environment through a map and then performed the egocentric pointing tasks in that environment under three conditions: with the heading aligned with the learning perspective (baseline), after 240° rotation from the baseline (updating), and after disorientation (disorientation). Disorientation disrupted the internal consistency of pointing among objects when the participants learned the sequentially displayed map, on which only one object name was displayed at a time while the location of “self” remained on the screen all the time. However, disorientation did not affect the internal consistency of pointing among objects when the participants learned the simultaneously displayed map. These results suggest that the egocentric representation can be acquired from a sequentially presented map. PMID:23555922

  1. Clinical laboratory data: acquire, analyze, communicate, liberate.

    PubMed

    Azzazy, Hassan M E; Elbehery, Ali H A

    2015-01-01

    The availability of portable healthcare devices, which can acquire and transmit medical data to remote experts would dramatically affect healthcare in areas with poor infrastructure. Smartphones, which feature touchscreen computer capabilities and sophisticated cameras, have become widely available with over billion units shipped in 2013. In the clinical laboratory, smartphones have recently brought the capabilities of key instruments such as spectrophotometers, fluorescence analyzers and microscopes into the palm of the hand. Several research groups have developed sensitive and low-cost smartphone-based diagnostic assay prototypes for testing cholesterol, albumin, vitamin D, tumor markers, and the detection of infectious agents. This review covers the use of smartphones to acquire, analyze, communicate, and liberate clinical laboratory data. Smartphones promise to dramatically improve the quality and quantity of healthcare offered in resource-limited areas. PMID:25172035

  2. Egocentric representation acquired from offline map learning.

    PubMed

    Xiao, Chengli; Zhang, Lei

    2013-01-01

    It is widely accepted that people establish allocentric spatial representation after learning a map. However, it is unknown whether people can directly acquire egocentric representation after map learning. In two experiments, the participants learned a distal environment through a map and then performed the egocentric pointing tasks in that environment under three conditions: with the heading aligned with the learning perspective (baseline), after 240° rotation from the baseline (updating), and after disorientation (disorientation). Disorientation disrupted the internal consistency of pointing among objects when the participants learned the sequentially displayed map, on which only one object name was displayed at a time while the location of "self" remained on the screen all the time. However, disorientation did not affect the internal consistency of pointing among objects when the participants learned the simultaneously displayed map. These results suggest that the egocentric representation can be acquired from a sequentially presented map. PMID:23555922

  3. Treatment of the acquired immune deficiency syndrome

    Microsoft Academic Search

    Sudhir Gupta; Michael S. Gottlieb

    1986-01-01

    The acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC) are sequelae of immune system injury initiated by a novel human retrovirus [human T-lymphotrophic virus strain III\\/lymphadenopathy-associated virus (HTLV III\\/LAV)]. The resulting spectrum of immune deficiency sets the stage for opportunistic infection and malignancy. In this review, we consider progress made in the treatment and prevention of AIDS and HTLV

  4. Total acquired vulval synechia: an unusual presentation.

    PubMed

    Kallam, Anji Reddy

    2015-04-01

    An unusual case of Acquired Total vulval synechia due to vulvar Lichen planus is reported in an 18-year-old girl, which is an extremely rare condition. It has a potential for producing extensive scarring and narrowing of introitus resulting in dyspareunia and rarely carcinoma of vulva. Successful surgical management of total vulvar synechiae in patient suffering from Lichen Planus is being reported. PMID:26023590

  5. Total Acquired Vulval Synechia: An Unusual Presentation

    PubMed Central

    2015-01-01

    An unusual case of Acquired Total vulval synechia due to vulvar Lichen planus is reported in an 18-year-old girl, which is an extremely rare condition. It has a potential for producing extensive scarring and narrowing of introitus resulting in dyspareunia and rarely carcinoma of vulva. Successful surgical management of total vulvar synechiae in patient suffering from Lichen Planus is being reported. PMID:26023590

  6. System Acquires Data On Reactivities Of Foams

    NASA Technical Reports Server (NTRS)

    Walls, Joe T.

    1994-01-01

    Data-acquisition and -plotting system, called DAPS(TM), developed enabling accurate and objective determination of physical properties related to reactivities of polyurethane and polyisocyanurate foams. Automated, computer-controlled test apparatus that acquires data on rates of rise, rise profiles, exothermic temperatures, and internal pressures of foams prepared from both manual and machine-mixed batches. Data used to determine minute differences between reaction kinetics and exothermic profiles of foam formulations, properties of end products which are statistically undifferentiated.

  7. Domestically acquired fascioliasis in northern California.

    PubMed

    Weisenberg, Scott A; Perlada, David E

    2013-09-01

    Two cases of domestically acquired fascioliasis are reported. Patient One was a 63-year-old male who developed a febrile illness 2 months after eating watercress in Marin County. Patient Two was a 38-year-old male who had eaten watercress with Patient One, and also developed a febrile illness. Both patients had eosinophilia and liver lesions on imaging. Diagnosis was made by serology and treatment was with triclabendazole. PMID:23836562

  8. The evolution of costly acquired immune memory

    PubMed Central

    Best, Alex; Hoyle, Andy

    2013-01-01

    A key feature of the vertebrate adaptive immune system is acquired immune memory, whereby hosts launch a faster and heightened response when challenged by previously encountered pathogens, preventing full infection. Here, we use a mathematical model to explore the role of ecological and epidemiological processes in shaping selection for costly acquired immune memory. Applying the framework of adaptive dynamics to the classic SIR (Susceptible-Infected-Recovered) epidemiological model, we focus on the conditions that may lead hosts to evolve high levels of immunity. Linking our work to previous theory, we show how investment in immune memory may be greatest at long or intermediate host lifespans depending on whether immunity is long lasting. High initial costs to gain immunity are also found to be essential for a highly effective immune memory. We also find that high disease infectivity and sterility, but intermediate virulence and immune period, increase selection for immunity. Diversity in host populations through evolutionary branching is found to be possible but only for a limited range of parameter space. Our model suggests that specific ecological and epidemiological conditions have to be met for acquired immune memory to evolve. PMID:23919164

  9. Motor considerations for turbomachinery

    SciTech Connect

    Halfpap, R.F.; Brotherhood, R. (Louis Allis Co., Milwaukee, WI (United States))

    1995-02-01

    Customers who use large rotating equipment realize motors can be subjected to hostile environmental conditions, nonstandard voltage levels and a variety of load requirements. The motor specifications they write reflect this change and have become far more detailed. Too often in the past, when large projects were being organized and highly technical equipment purchased, induction motors were thought of as standard pieces of equipment not requiring much in the way of specialized design. High-speed compressor applications are good examples of the need for specific compressor torque characteristics and starting requirements to allow for proper motor design. Not only different compressor designs, but adjustments in compressor valves and changes in gas process conditions, can produce a diversity of speed-torque curves. Therefore, it is not practical for a motor designer to be told to assume a standard compressor load torque during acceleration. An example of compressor speed-torque curves illustrates this point. The paper also presents the example of centrifugal pumps to further illustrate the need for properly matching driver torque and power requirements.

  10. Fusion for Neutrons as a Necessary Step to Commercial Fusion

    E-print Network

    1 Fusion for Neutrons as a Necessary Step to Commercial Fusion B. Kuteev Head of Fusion Reactor" MFERW, Princeton, NJ, USA, September 7-10, 2011 #12; Renewal of interest to fusion neutrons Growing interest to steady state operations, which are urgently needed for applications of fusion neutrons Several

  11. Design and prototyping methods for brushless motors and motor control

    E-print Network

    Colton, Shane W. (Shane William)

    2010-01-01

    In this report, simple, low-cost design and prototyping methods for custom brushless permanent magnet synchronous motors are explored. Three case-study motors are used to develop, illustrate and validate the methods. Two ...

  12. Motor current signature analysis method for diagnosing motor operated devices

    DOEpatents

    Haynes, Howard D. (Kingston, TN); Eissenberg, David M. (Oak Ridge, TN)

    1990-01-01

    A motor current noise signature analysis method and apparatus for remotely monitoring the operating characteristics of an electric motor-operated device such as a motor-operated valve. Frequency domain signal analysis techniques are applied to a conditioned motor current signal to distinctly identify various operating parameters of the motor driven device from the motor current signature. The signature may be recorded and compared with subsequent signatures to detect operating abnormalities and degradation of the device. This diagnostic method does not require special equipment to be installed on the motor-operated device, and the current sensing may be performed at remote control locations, e.g., where the motor-operated devices are used in accessible or hostile environments.

  13. Basics of AC Motors

    NSDL National Science Digital Library

    This course is one of the quickStep series offered by Siemens in AC Motors. These are FREE on-line industrial knowledge building tutorials. quickSTEPs are a great start for industry novices moving into technical jobs or staff in operational support rolls. They can also be very effectively used as out of class assignments for review or to build fundamental skills. Each course includes: an online tutorial organized as a number of units, lessons with self check quiz questions, a glossary of terms, a self-check final exam with scoring, an extensive downloadable PDF study guide. This course covers: motor basics, NEMA motors, Siemens motorr, final exam, a glossary, plus a 116 page study guide.

  14. RESEARCH HIGHLIGHTS State of fusion

    E-print Network

    Loss, Daniel

    RESEARCH HIGHLIGHTS State of fusion In the 1950s,the promise of controlled nuclear fusion, although there is still some way to go to realize the dream,the latest status report on fusion research compiled by the International Fusion Research Council (Nucl. Fusion 45,A1­A28; 2005) provides good reason

  15. Central motor conduction is abnormal in motor neuron disease

    Microsoft Academic Search

    D A Ingram; M Swash

    1987-01-01

    Conduction in the central motor pathways of the brain and spinal cord was studied in 12 patients with motor neuron disease. Six healthy volunteers served as controls. Transcutaneous electrical stimulation of the cortex, cervical cord, thoracic cord and conus medullaris was used to determine motor latencies to the biceps brachii, thenar eminence and tibialis anterior muscles. Prominent, and often asymmetrical,

  16. Fusion Energy Education

    NSDL National Science Digital Library

    The basics of fusion are deceptively simple: the process powers the sun and other stars, and it all takes place when atomic nuclei collide at high speed. But many questions remain. How can humans develop and exploit fusion energy? Is there a way to convert it more efficiently into useful mechanical, electrical, or thermal energy? This intriguing site, created by the Lawrence Livermore National Laboratory and the Princeton Plasma Physics Laboratory, presents an online fusion course designed to teach students and others about how fusion works and how it might be harnessed in the future. Visitors can try out The Guided Tour to get started, or they can click on one of the Main Topics. These include Energy Sources and Conversions, Two Key Fusion Reactions, and Creating the Conditions for Fusion. Each section contains graphics, explanatory text, and various diagrams. The site also includes charts which can be printed out for classroom use.

  17. Electric motor model repair specifications

    SciTech Connect

    NONE

    1995-08-01

    These model repair specifications list the minimum requirements for repair and overhaul of polyphase AC squireel cage induction motors. All power ranges, voltages, and speeds of squirrel cage motors are covered.

  18. Evaluating High Efficiency Motor Retrofit 

    E-print Network

    Evans, T. A.

    1984-01-01

    In the petrochemical and refining Industries, and most manufacturing plants, the reliable operation of AC motors always has been crucial to the continuous operation of the process. Now, the cost of operating these motors has also become a...

  19. Fusion facility siting considerations

    NASA Astrophysics Data System (ADS)

    Bussell, G. T.

    1985-02-01

    Inherent in the fusion program's transition from hydrogen devices to commercial power machines is a general increase in the size and scope of succeeding projects. This growth will lead to increased emphasis on safety, environmental impact, and the external effects of fusion in general, and of each new device in particular. An important consideration in this regard is site selection. Major siting issues that may affect the economics, safety, and environmental impact of fusion are examined.

  20. Multisensor Data Fusion

    Microsoft Academic Search

    Pramod K. Varshney

    2000-01-01

    Multisensor data fusion is a key enabling technology in which information from a number of sources is integrated to form a\\u000a unified picture [1]. This concept has been applied to numerous fields and new applications are being explored constantly. Even though most multisensor\\u000a data fusion applications have been developed relatively recently, the notion of data fusion has always been around.

  1. Gas-operated motor systems

    SciTech Connect

    Rilett, J.W.

    1980-09-30

    A gas-operated motor system of the stored energy type-as disclosed in U.S. Pat. No. 4,092,830-in which the gas exhausted from the motor is ducted to a chamber during operation of the motor and thereafter compressed back into the gas reservoir vessel. Recompression may be achieved, e.g., by providing the exhaust gas chamber with a movable piston, or by running the motor in the reverse mode as a compressor.

  2. Filament depolymerization by motor molecules

    E-print Network

    Gernot A. Klein; Karsten Kruse; Gianaurelio Cuniberti; Frank Juelicher

    2005-01-24

    Motor proteins that specifically interact with the ends of cytoskeletal filaments can induce filament depolymerization. A phenomenological description of this process is presented. We show that under certain conditions motors dynamically accumulate at the filament ends. We compare simulations of two microscopic models to the phenomenological description. The depolymerization rate can exhibit maxima and dynamic instabilities as a function of the bulk motor density for processive depolymerization. We discuss our results in relation to experimental studies of Kin-13 family motor proteins.

  3. A CMA position. Acquired immunodeficiency syndrome.

    PubMed Central

    1989-01-01

    The following general principles serve as guidelines for various bodies, health care professionals and the general public. Specific aspects of infection with human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) that relate to physicians' ethical responsibilities as well as society's moral obligations are discussed. Such matters include the need for education, research and treatment resources; the patient's right to investigation and treatment and to refusal of either; the need to obtain the patient's informed consent; the right to privacy and confidentiality; the importance of infection control; and the right to financial compensation in the case of occupational exposure to HIV. PMID:2909275

  4. Acquired hemophilia A: emerging treatment options

    PubMed Central

    Janbain, Maissaa; Leissinger, Cindy A; Kruse-Jarres, Rebecca

    2015-01-01

    Acquired hemophilia A is a rare autoimmune disorder caused by an autoantibody (inhibitor) to factor VIII (FVIII) that interferes with its coagulant function and predisposes to severe, potentially life-threatening hemorrhage. Disease management focuses on controlling bleeding, primarily with the use of bypassing therapy and recombinant porcine FVIII, and permanently eradicating the autoantibody using various immunosuppressants. Treatment challenges include delayed diagnosis, difficulty achieving hemostasis and durable remissions, and complications associated with the use of hemostatic and immunosuppressive therapy in a primarily older patient population. PMID:26056504

  5. Common acquired causes of thrombosis in children.

    PubMed

    Tolbert, Jaszianne; Carpenter, Shannon L

    2013-08-01

    Compared to adults, venous thromboembolism in the pediatric population is a rare event. Cancer, cardiac disease, antiphospholipid antibodies, and indwelling catheters are established risk factors for thromboembolism in children. We examined the literature related to thrombophilia in children, childhood cancer and thrombosis, cardiac disease and thrombosis, and antiphospholipid antibody syndrome in children. Citations in identified articles yielded additional articles for review. We found that studies of acquired thrombophilia in children are limited. Current treatment for thromboembolism in children is based on adult data therefore optimal treatment in this population remains unclear. PMID:23890024

  6. [Acute polyradiculoneuritis and acquired immunodeficiency virus].

    PubMed

    Scaff, M; Rabello, G D; Marchiori, P E

    1989-03-01

    A 50-year-old man with positive test for human immunodeficiency virus (HIV) by enzyme-linked-immunoassy and Western-blot, without clinical manifestations of acquired immunodeficiency syndrome (AIDS), developed acute polyradiculoneuritis and was treated by plasmapheresis with improvement. We believe that chemical homologies of antigenic determinants between HIV and P2 protein of peripheral nervous system and myelin basic protein may induce crossed-reaction, thus developing acute polyradiculoneuritis and central nervous system involvement, respectively. The nervous system involvement hy HIV also occur in the HI-viremy, seric conversion alone, and AIDS with or without oportunistic infections. PMID:2764748

  7. Triple arthrodesis for adult acquired flatfoot.

    PubMed

    Catanzariti, Alan R; Dix, Brian T; Richardson, Phillip E; Mendicino, Robert W

    2014-07-01

    The primary goal of triple arthrodesis for stage III and IV adult acquired flatfoot is to obtain a well-aligned plantigrade foot that will support the ankle in optimal alignment. Ancillary procedures including posterior muscle group lengthening, medial displacement calcaneal osteotomy, medial column stabilization, peroneus brevis tenotomy, or transfer and harvest of regional bone graft are often necessary to achieve adequate realignment. Image intensification is helpful in confirming optimal realignment before fixation. Results of triple arthrodesis are enhanced with adequate preparation of joint surfaces, bone graft/orthobiologics, 2-point fixation of all 3 tritarsal joints, and a vertical heel position. PMID:24980931

  8. Psychological issues in acquired facial trauma

    PubMed Central

    De Sousa, Avinash

    2010-01-01

    The face is a vital component of one’s personality and body image. There are a vast number of variables that influence recovery and rehabilitation from acquired facial trauma many of which are psychological in nature. The present paper presents the various psychological issues one comes across in facial trauma patients. These may range from body image issues to post-traumatic stress disorder symptoms accompanied by anxiety and depression. Issues related to facial and body image affecting social life and general quality of life are vital and the plastic surgeon should be aware of such issues and competent to deal with them in patients and families. PMID:21217982

  9. Description of the Motor Development of 3-12 Month Old Infants with Down Syndrome: The Influence of the Postural Body Position

    ERIC Educational Resources Information Center

    Tudella, Eloisa; Pereira, Karina; Basso, Renata Pedrolongo; Savelsbergh, Geert J. P.

    2011-01-01

    The purpose of the present study was to describe the rate of motor development in infants with Down syndrome in the age range of 3-12 months and identify the difficulties both in performance and acquiring motor skills in prone, supine, sitting and standing positions. Nineteen infants with Down syndrome and 25 healthy full term typical infants were…

  10. Brushed Motor Test Spring 2011

    E-print Network

    Ruina, Andy L.

    . Additional data (motor velocity and current, and battery, current, velocity and voltage) was collected using Cornell University #12;In this test, a brushed motor, like the ones currently used in the robot Ranger: What does "PWM" mean here? #12;Figure 2 Comparison of current when motor spins positive and negative

  11. Spotting drives for large motors

    Microsoft Academic Search

    B. Dick

    2002-01-01

    High power line-fed, constant speed motors sometimes must be operated at very low speed for controlled positioning of the attached load equipment. This process is referred to as 'spotting' or 'inching'. Examples include cement grinding mills (both raw and finish) and metal processing rolls. These motors are usually medium voltage (>2300 V). Two methods of spotting motors have been used

  12. Passenger car motor oils

    SciTech Connect

    Not Available

    1989-01-01

    This book contains proceedings of a conference on passenger car motor oil. Topics covered include: Analysis of oil consumption mechanism by measuring oil rims radial movement; Base oil effects in sequence IIID and sequence V-D engine tests; Study of transient oil consumption of automotive engines; and SI engine warm-up: Water and lubricating oil temperature influences.

  13. Vesicles as Osmotic Motors

    NASA Astrophysics Data System (ADS)

    Nardi, J.; Bruinsma, R.; Sackmann, E.

    1999-06-01

    We report on a quantitative study of the motion of model osmotic motors-lipid vesicles in a solute concentration gradient. The vesicles move through recoil produced by osmotic pumping, but the transformation of entropic osmotic energy into mechanical motion is found to be unexpectedly efficient: The drift velocity is more than 3 orders of magnitude faster than predicted by linearized nonequilibrium thermodynamics.

  14. Reciprocating Linear Electric Motor

    NASA Technical Reports Server (NTRS)

    Goldowsky, M. P.

    1984-01-01

    Features include structural simplicity and good force/displacement characteristics. Reciprocating motor has simple, rugged construction, relatively low reciprocating weight, improved power delivery, and improved force control. Wear reduced by use of magnetic bearings. Intended to provide drivers for long-lived Stirling-cycle cryogenic refrigerators, concept has less exotic applications, such as fuel pumps.

  15. The St. Louis Motor

    ERIC Educational Resources Information Center

    Greenslade, Thomas B., Jr.

    2011-01-01

    The St. Louis Motor, invented in 1909, is unique among physics apparatus for being named for a geographical place rather than a physicist. The sturdy little device (Fig. 1) has never been out of production. Any older school or physics department that has not done a catastrophic housecleaning in the last 20 years will certainly have a small flock…

  16. Thiokol Solid Rocket Motors

    NASA Technical Reports Server (NTRS)

    Graves, S. R.

    2000-01-01

    This paper presents viewgraphs on thiokol solid rocket motors. The topics include: 1) Communications; 2) Military and government intelligence; 3) Positioning satellites; 4) Remote sensing; 5) Space burial; 6) Science; 7) Space manufacturing; 8) Advertising; 9) Space rescue space debris management; 10) Space tourism; 11) Space settlements; 12) Hazardous waste disposal; 13) Extraterrestrial resources; 14) Fast package delivery; and 15) Space utilities.

  17. Metacognition in Motor Learning

    Microsoft Academic Search

    Dominic A. Simon; Robert A. Bjork

    2001-01-01

    Research on judgments of verbal learning has demonstrated that participants' judgments are unreliable and often overconfident. The authors studied judgments of perceptual–motor learning. Participants learned 3 keystroke patterns on the number pad of a computer, each requiring that a different sequence of keys be struck in a different total movement time. Practice trials on each pattern were either blocked or

  18. ams2000.com Stepper Motor System Basics

    E-print Network

    Bechtold, Jill

    . STEPPING MOTORS TYPES OF STEPPING MOTORS VARIABLE RELUCTANCE PERMANENT MAGNET HYBRID MOTOR WINDINGS MOTORS There are basically three types of stepping motors; variable reluctance, permanent magnet with laminated steel stators. VARIABLE RELUCTANCE The variable reluctance motor does not use a permanent magnet

  19. Electric drive system with BLDC motor

    Microsoft Academic Search

    Lin Bai

    2011-01-01

    With the resource supply becoming severe recently, the use of hybrid car or electric car is a necessity that it can reduce the need of oil. This paper presents BLDC motor is the best choice for high-efficiency motor and shows a design of control system for BLDC motor. With the comparison of DC motor, Induction Motor and BLDC motor, Analysis

  20. Coordinated switching of bacterial flagellar motors: evidence for direct motor-motor coupling?

    PubMed Central

    Hu, Bo; Tu, Yuhai

    2013-01-01

    The swimming of Escherichia coli is powered by its multiple flagellar motors. Each motor spins either clockwise (CW) or counterclockwise (CCW), under the control of an intracellular regulator, CheY-P. There can be two mechanisms (extrinsic and intrinsic) to coordinate the switching of bacterial motors. The extrinsic one arises from the fact that different motors in the same cell sense a common input (CheY-P) which fluctuates near the motors' response threshold. An alternative, intrinsic mechanism is direct motor-motor coupling which makes synchronized switching energetically favorable. Here, we develop simple models for both mechanisms and uncover their different hallmarks. A quantitative comparison to the recent experiments suggest that the direct coupling mechanism may be accountable for the observed sharp correlation between motors in a single E. coli. Possible origins of this coupling (e.g., hydrodynamic interaction) are discussed. PMID:25167320

  1. Toward relating the subthalamic nucleus spiking activity to the local field potentials acquired intranuclearly

    NASA Astrophysics Data System (ADS)

    Michmizos, K. P.; Sakas, D.; Nikita, K. S.

    2011-11-01

    Studies on neurophysiological correlates of the functional magnetic resonance imaging (fMRI) signals reveal a strong relationship between the local field potential (LFP) acquired invasively and metabolic signal changes in fMRI experiments. Most of these studies failed to reveal an analogous relationship between metabolic signals and the spiking activity. That would allow for the prediction of the neural activity exclusively from the fMRI signals. However, the relationship between fMRI signals and spiking activity can be inferred indirectly provided that the LFPs can be used to predict the spiking activity of the area. Until now, only the LFP-spike relationship in cortical areas has been examined. Herein, we show that the spiking activity can be predicted by the LFPs acquired in a deep nucleus, namely the subthalamic nucleus (STN), using a nonlinear cascade model. The model can reproduce the spike patterns inside the motor area of the STN that represent information about the motor plans. Our findings expand the possibility of further recruiting non-invasive neuroimaging techniques to understand the activity of the STN and predict or even control movement.

  2. Motor Controller System For Large Dynamic Range of Motor Operation

    NASA Technical Reports Server (NTRS)

    Howard, David E. (Inventor); Alhorn, Dean C. (Inventor); Smith, Dennis A. (Inventor); Dutton, Kenneth R. (Inventor); Paulson, Mitchell Scott (Inventor)

    2006-01-01

    A motor controller system uses a rotary sensor with a plurality of signal conditioning units, coupled to the rotary sensor. Each of these units, which is associated with a particular range of motor output shaft rotation rates, generate a feedback signal indicative of the position of the motor s output shaft. A controller (i) converts a selected motor output shaft rotation rate to a corresponding incremental amount of rotational movement for a selected fixed time period, (ii) selects, at periodic completions of the selected fixed time period, the feedback signal from one of the signal conditioning units for which the particular range of motor output shaft rotation rates associated therewith encompasses the selected motor output shaft rotation rate, and (iii) generates a motor drive signal based on a difference between the incremental amount of rotational movement and the feedback signal from the selected one of the signal conditioning Units.

  3. Software for Acquiring Image Data for PIV

    NASA Technical Reports Server (NTRS)

    Wernet, Mark P.; Cheung, H. M.; Kressler, Brian

    2003-01-01

    PIV Acquisition (PIVACQ) is a computer program for acquisition of data for particle-image velocimetry (PIV). In the PIV system for which PIVACQ was developed, small particles entrained in a flow are illuminated with a sheet of light from a pulsed laser. The illuminated region is monitored by a charge-coupled-device camera that operates in conjunction with a data-acquisition system that includes a frame grabber and a counter-timer board, both installed in a single computer. The camera operates in "frame-straddle" mode where a pair of images can be obtained closely spaced in time (on the order of microseconds). The frame grabber acquires image data from the camera and stores the data in the computer memory. The counter/timer board triggers the camera and synchronizes the pulsing of the laser with acquisition of data from the camera. PIVPROC coordinates all of these functions and provides a graphical user interface, through which the user can control the PIV data-acquisition system. PIVACQ enables the user to acquire a sequence of single-exposure images, display the images, process the images, and then save the images to the computer hard drive. PIVACQ works in conjunction with the PIVPROC program which processes the images of particles into the velocity field in the illuminated plane.

  4. Gross motor skill acquisition in adolescents with Down syndrome.

    PubMed

    Meegan, Sarah; Maraj, Brian K V; Weeks, Daniel; Chua, Romeo

    2006-06-01

    The purpose of this study was to assess whether verbal-motor performances deficits exhibited by individuals with Down syndrome limited their ability to acquire gross motor skills when given visual and verbal instruction together and then transferred to either a visual or verbal instructional mode to reproduce the movement. Nine individuals with Down syndrome (6 males, 3 females) performed 3 gross motor skills. Both visual and verbal instructional guidance was given to the participants over a 4-day period. Twenty-four hours later, the participants were video recorded as they produced the movements (used as baseline measures). On Day 6, they were randomly assigned into verbal and visual groups and required to reproduce the skills while the experimenter provided either visual demonstration or verbal instructions depending on the group. Based on skill performance scores, participants in the verbal-motor performance group demonstrated a lower level of proficiency and an increased number of performance errors when compared to participants in the visual-motor performance group. Moreover, while the visual group demonstrated an increase in performance levels compared to baseline measures, the opposite effect was seen for the verbal group. PMID:16869378

  5. Similar Cerebral Motor Plans for Real and Virtual Actions

    PubMed Central

    Bozzacchi, Chiara; Giusti, Maria Assunta; Pitzalis, Sabrina; Spinelli, Donatella; Di Russo, Francesco

    2012-01-01

    A simple movement, such as pressing a button, can acquire different meanings by producing different consequences, such as starting an elevator or switching a TV channel. We evaluated whether the brain activity preceding a simple action is modulated by the expected consequences of the action itself. To further this aim, the motor-related cortical potentials were compared during two key-press actions that were identical from the kinematics point of view but different in both meaning and consequences. In one case (virtual grasp), the key-press started a video clip showing a hand moving toward a cup and grasping it; in the other case, the key-press did not produce any consequence (key-press). A third condition (real grasp) was also compared, in which subjects actually grasped the cup, producing the same action presented in the video clip. Data were collected from fifteen subjects. The results showed that motor preparation for virtual grasp (starting 3 s before the movement onset) was different from that of the key-press and similar to the real grasp preparation–as if subjects had to grasp the cup in person. In particular, both virtual and real grasp presented a posterior parietal negativity preceding activity in motor and pre-motor areas. In summary, this finding supports the hypothesis that motor preparation is affected by the meaning of the action, even when the action is only virtual. PMID:23112847

  6. Fusion Plasma Performance Required for Fusion Power The performance achieved on MFE and IFE fusion experiments using DT fuel is compared with the fusion performance

    E-print Network

    Fusion Plasma Performance Required for Fusion Power The performance achieved on MFE and IFE fusion experiments using DT fuel is compared with the fusion performance required for a Fusion Power Plant. Const. Cost $B Date

  7. Clinical Outcome and Fusion Rates after the First 30 Extreme Lateral Interbody Fusions

    PubMed Central

    Malham, Gregory M.; Ellis, Ngaire J.; Parker, Rhiannon M.; Seex, Kevin A.

    2012-01-01

    Introduction. The lateral transpsoas approach for lumbar interbody fusion (XLIF) is gaining popularity. Studies examining a surgeon's early experience are rare. We aim to report treatment, complication, clinical, and radiographic outcomes in an early series of patients. Methods. Prospective data from the first thirty patients treated with XLIF by a single surgeon was reviewed. Outcome measures included pain, disability, and quality of life assessment. Radiographic assessment of fusion was performed by computed tomography. Results. Average follow-up was 11.5 months, operative time was 60 minutes per level and blood loss was 50?mL. Complications were observed: clinical subsidence, cage breakage upon insertion, new postoperative motor deficit and bowel injury. Approach side-effects were radiographic subsidence and anterior thigh sensory changes. Two patients required reoperation; microforaminotomy and pedicle screw fixation respectively. VAS back and leg pain decreased 63% and 56%, respectively. ODI improved 41.2% with 51.3% and 8.1% improvements in PCS and MCS. Complete fusion (last follow-up) was observed in 85%. Conclusion. The XLIF approach provides superior treatment, clinical outcomes and fusion rates compared to conventional surgical approaches with lowered complication rates. Mentor supervision for early cases and strict adherence to the surgical technique including neuromonitoring is essential. PMID:23213282

  8. Neural net sensor fusion

    Microsoft Academic Search

    R. Y. Levine; T. S. Khuon

    1991-01-01

    A generic architecture for neural net multisensor data fusion is introduced and analyzed. The architecture consists of a set of independent sensor neural nets, one for each sensor, coupled to a fusion net. Each sensor is trained (from a representative data set of the particular sensor) to map to a hypothesis space output. The decision outputs from the sensor nets

  9. Fusion welding process

    Microsoft Academic Search

    E. D. Jones; M. A. Mcbride; K. C. Thomas

    1983-01-01

    A process for the fusion welding of nickel alloy steel members wherein a ferrite containing pellet is inserted into a cavity in one member and melted by a welding torch. The resulting weld nugget, a fusion of the nickel containing alloy from the members to be welded and the pellet, has a composition which is sufficiently low in nickel content

  10. Coatings for laser fusion

    SciTech Connect

    Lowdermilk, W.H.

    1981-12-18

    Optical coatings are used in lasers systems for fusion research to control beam propagation and reduce surface reflection losses. The performance of coatings is important in the design, reliability, energy output, and cost of the laser systems. Significant developments in coating technology are required for future lasers for fusion research and eventual power reactors.

  11. Spherical torus fusion reactor

    Microsoft Academic Search

    Martin Peng; Y. K. M

    1985-01-01

    The object of this invention is to provide a compact torus fusion reactor with dramatic simplification of plasma confinement design. Another object of this invention is to provide a compact torus fusion reactor with low magnetic field and small aspect ratio stable plasma confinement. In accordance with the principles of this invention there is provided a compact toroidal-type plasma confinement

  12. Aspects of Phonological Fusion

    ERIC Educational Resources Information Center

    Cutting, James E.

    1975-01-01

    Phonological fusion occurs when the phonemes of two different speech stimuli are combined into a new percept that is longer and linguistically more complex than either of the two inputs. The present article is an investigation of the conditions necessary and sufficient for fusion to occur. (Editor/RK)

  13. Robotics and local fusion

    Microsoft Academic Search

    Philip J. Emmerman

    2005-01-01

    Teams of robots or mixed teams of warfighters and robots on reconnaissance and other missions can benefit greatly from a local fusion station. A local fusion station is defined here as a small mobile processor with interfaces to enable the ingestion of multiple heterogeneous sensor data and information streams, including blue force tracking data. These data streams are fused and

  14. Controlled Nuclear Fusion.

    ERIC Educational Resources Information Center

    Glasstone, Samuel

    This publication is one of a series of information booklets for the general public published by The United States Atomic Energy Commission. Among the topics discussed are: Importance of Fusion Energy; Conditions for Nuclear Fusion; Thermonuclear Reactions in Plasmas; Plasma Confinement by Magnetic Fields; Experiments With Plasmas; High-Temperature…

  15. Total wrist fusion

    Microsoft Academic Search

    J. Field; T. J. Herbert; R. Prosser

    1996-01-01

    Twenty cases of total wrist fusion, performed for post-traumatic conditions, were reviewed objectively, subjectively and radiologically. All patients were satisfied with the position of the fused wrist and had good pain relief. All patients would have had the procedure sooner, having had an average of three operations on the wrist before the fusion. There was a high complication rate (45%),

  16. Muon-catalyzed fusion

    Microsoft Academic Search

    W. H. Breunlich; P. Kammel; J. S. Cohen; M. Leon

    1989-01-01

    Great progress achieved in muon-catalyzed fusion research in the past decade now makes it possible to review careful quantitative calculations and measurements. The major experimental surprises have doubled the fusion yields, but direct energy production would appear to be excluded without a significant breakthrough.(AIP)

  17. Muon catalysed fusion

    Microsoft Academic Search

    L. I. Ponomarev

    1990-01-01

    A decade ago it was established that one muon in a deuterium-tritium mixture can catalyse more than 100 nuclear fusion reactions and that this phenomenon could be used for the production of nuclear fuel and energy. This review presents the state of the art of muon catalysed fusion studies and its place among alternative methods of nuclear breeding. The main

  18. Inertial fusion reactors (review)

    Microsoft Academic Search

    A V Kalinin

    1984-01-01

    The current status of the work on engineering problems of inertial fusion is reviewed. The state of laboratory physics research, aspects of driver choice, and pellet designs are discussed. Particular attention is paid to the development of inertial fusion reactors and their energy applications. It is shown that lasers with output energies in the 0.5-5.0 MJ range must be acknowledged

  19. Presented by Information Fusion

    E-print Network

    Information Fusion at ORNL · ORNL Instrumental in formulating and fostering this multi-disciplinary area by ASCR Statistics Program ­ Cyber-physical networks ­ ASCR Applied Math Program 2009 - present · Foundational work at ORNL: ­ Showed tractability of generic information fusion problem using measurements

  20. Improving Human Plateaued Motor Skill with Somatic Stimulation

    PubMed Central

    Nambu, Isao; Tomatsu, Saeka; Lee, Jongho; Kakei, Shinji

    2011-01-01

    Procedural motor learning includes a period when no substantial gain in performance improvement is obtained even with repeated, daily practice. Prompted by the potential benefit of high-frequency transcutaneous electrical stimulation, we examined if the stimulation to the hand reduces redundant motor activity that likely exists in an acquired hand motor skill, so as to further upgrade stable motor performance. Healthy participants were trained until their motor performance of continuously rotating two balls in the palm of their right hand became stable. In the series of experiments, they repeated a trial performing this cyclic rotation as many times as possible in 15 s. In trials where we applied the stimulation to the relaxed thumb before they initiated the task, most reported that their movements became smoother and they could perform the movements at a higher cycle compared to the control trials. This was not possible when the dorsal side of the wrist was stimulated. The performance improvement was associated with reduction of amplitude of finger displacement, which was consistently observed irrespective of the task demands. Importantly, this kinematic change occurred without being noticed by the participants, and their intentional changes of motor strategies (reducing amplitude of finger displacement) never improved the performance. Moreover, the performance never spontaneously improved during one-week training without stimulation, whereas the improvement in association with stimulation was consistently observed across days during training on another week combined with the stimulation. The improved effect obtained in stimulation trials on one day partially carried over to the next day, thereby promoting daily improvement of plateaued performance, which could not be unlocked by the first-week intensive training. This study demonstrated the possibility of effectively improving a plateaued motor skill, and pre-movement somatic stimulation driving this behavioral change. PMID:21991331

  1. Increased cortico-striatal connectivity during motor practice contributes to the consolidation of motor memory in writer's cramp patients

    PubMed Central

    Gallea, C.; Balas, M.; Bertasi, E.; Valabregue, R.; García-Lorenzo, D.; Coynel, D.; Bonnet, C.; Grabli, D.; Pélégrini-Issac, M.; Doyon, J.; Benali, H.; Roze, E.; Vidailhet, M.; Lehericy, S.

    2015-01-01

    Sensorimotor representations of movements are created in the sensorimotor network through repeated practice to support successful and effortless performance. Writer's cramp (WC) is a disorder acquired through extensive practice of finger movements, and it is likely associated with the abnormal acquisition of sensorimotor representations. We investigated (i) the activation and connectivity changes in the brain network supporting the acquisition of sensorimotor representations of finger sequences in patients with WC and (ii) the link between these changes and consolidation of motor performance 24 h after the initial practice. Twenty-two patients with WC and 22 age-matched healthy volunteers practiced a complex sequence with the right (pathological) hand during functional MRI recording. Speed and accuracy were measured immediately before and after practice (day 1) and 24 h after practice (day 2). The two groups reached equivalent motor performance on day 1 and day 2. During motor practice, patients with WC had (i) reduced hippocampal activation and hippocampal–striatal functional connectivity; and (ii) overactivation of premotor–striatal areas, whose connectivity correlated with motor performance after consolidation. These results suggest that patients with WC use alternative networks to reach equiperformance in the acquisition of new motor memories.

  2. Motors and Bulbs in Series

    NASA Astrophysics Data System (ADS)

    Whitaker, Robert J.

    2009-09-01

    One of Paul Hewitt's "Figuring Physics" that appeared in this journal dealt with the heating of a motor. This phenomenon can be demonstrated with a miniature motor and a bulb as part of a series of activities with "batteries and bulbs." Students examine the effect on the brightness of a single bulb when a second, identical bulb is placed in series with it (Fig. 1). The second bulb is then replaced with the motor (Fig. 2). When the motor is running, the first bulb is dimmer than it was in series with the other bulb. However, if the shaft of the motor is held so it cannot move (like Hewitt's saw motor), the bulb is noticeably brighter. If one uses the brightness of the bulb as a qualitative measure of current, then there is clearly more current when the motor is not moving. This provides an opportunity to introduce some very interesting physics.

  3. Online and Offline Rotary Regression Analysis of Torque Estimator for Switched Reluctance Motor Drives

    Microsoft Academic Search

    X. D. Xue; K. W. E. Cheng; S. L. Ho

    2007-01-01

    A new torque estimator for switched reluctance motor (SRM) drives based on 2-D rotary regression analysis is presented in this paper. The proposed torque estimator is composed of a bicubic regressive polynomial as a function of rotor position and input current. The regressive coefficients can be computed offline or online from the torque characteristics acquired either experimentally or from numerical

  4. An Internet-Based Telerehabilitation System for the Assessment of Motor Speech Disorders: A Pilot Study

    ERIC Educational Resources Information Center

    Hill, Anne J.; Theodoros, Deborah G.; Russell, Trevor G.; Cahill, Louise M.; Ward, Elizabeth C.; Clark, Kathy M.

    2006-01-01

    Purpose: This pilot study explored the feasibility and effectiveness of an Internet-based telerehabilitation application for the assessment of motor speech disorders in adults with acquired neurological impairment. Method: Using a counterbalanced, repeated measures research design, 2 speech-language pathologists assessed 19 speakers with…

  5. Corticosteroid treatment of behaviour, language and motor regression in childhood disintegrative disorder.

    PubMed

    Mordekar, Santosh R; Prendergast, Michael; Chattopadhyay, Arup K; Baxter, Peter S

    2009-07-01

    Childhood disintegrative disorder (CDD) (ICD-10 F84.3) is defined by a period of normal development before onset followed by gradual loss of previously acquired skills with the development of characteristic abnormalities of social, communicative and behavioural functioning. We report two children with apparent CDD, who showed amelioration of behaviour, language and motor regression after corticosteroid treatment. PMID:18625572

  6. An Extended Motor Network Generates Beta and Gamma Oscillatory Perturbations during Development

    ERIC Educational Resources Information Center

    Wilson, Tony W.; Slason, Erin; Asherin, Ryan; Kronberg, Eugene; Reite, Martin L.; Teale, Peter D.; Rojas, Donald C.

    2010-01-01

    This study examines the time course and neural generators of oscillatory beta and gamma motor responses in typically-developing children. Participants completed a unilateral flexion-extension task using each index finger as whole-head magnetoencephalography (MEG) data were acquired. These MEG data were imaged in the frequency-domain using spatial…

  7. Fusion excitation function revisited

    E-print Network

    Ph. Eudes; Z. Basrak; F. Sébille; V. de la Mota; G. Royer; M. Zori?

    2012-09-28

    We report on a comprehensive systematics of fusion-evaporation and/or fusion-fission cross sections for a very large variety of systems over an energy range 4-155 A.MeV. Scaled by the reaction cross sections, fusion cross sections do not show a universal behavior valid for all systems although a high degree of correlation is present when data are ordered by the system mass asymmetry.For the rather light and close to mass-symmetric systems the main characteristics of the complete and incomplete fusion excitation functions can be precisely determined. Despite an evident lack of data above 15A.MeV for all heavy systems the available data suggests that geometrical effects could explain the persistence of incomplete fusion at incident energies as high as 155A.MeV.

  8. Robotics and local fusion

    NASA Astrophysics Data System (ADS)

    Emmerman, Philip J.

    2005-05-01

    Teams of robots or mixed teams of warfighters and robots on reconnaissance and other missions can benefit greatly from a local fusion station. A local fusion station is defined here as a small mobile processor with interfaces to enable the ingestion of multiple heterogeneous sensor data and information streams, including blue force tracking data. These data streams are fused and integrated with contextual information (terrain features, weather, maps, dynamic background features, etc.), and displayed or processed to provide real time situational awareness to the robot controller or to the robots themselves. These blue and red force fusion applications remove redundancies, lessen ambiguities, correlate, aggregate, and integrate sensor information with context such as high resolution terrain. Applications such as safety, team behavior, asset control, training, pattern analysis, etc. can be generated or enhanced by these fusion stations. This local fusion station should also enable the interaction between these local units and a global information world.

  9. Thermal Resonance Fusion

    E-print Network

    Bao-Guo Dong

    2015-07-07

    We first show a possible mechanism to create a new type of nuclear fusion, thermal resonance fusion, i.e. low energy nuclear fusion with thermal resonance of light nuclei or atoms, such as deuterium or tritium. The fusion of two light nuclei has to overcome the Coulomb barrier between these two nuclei to reach up to the interacting region of nuclear force. We found nuclear fusion could be realized with thermal vibrations of crystal lattice atoms coupling with light atoms at low energy by resonance to overcome this Coulomb barrier. Thermal resonances combining with tunnel effects can greatly enhance the probability of the deuterium fusion to the detectable level. Our low energy nuclear fusion mechanism research - thermal resonance fusion mechanism results demonstrate how these light nuclei or atoms, such as deuterium, can be fused in the crystal of metal, such as Ni or alloy, with synthetic thermal vibrations and resonances at different modes and energies experimentally. The probability of tunnel effect at different resonance energy given by the WKB method is shown that indicates the thermal resonance fusion mode, especially combined with the tunnel effect, is possible and feasible. But the penetrating probability decreases very sharply when the input resonance energy decreases less than 3 keV, so for thermal resonance fusion, the key point is to increase the resonance peak or make the resonance sharp enough to the acceptable energy level by the suitable compound catalysts, and it is better to reach up more than 3 keV to make the penetrating probability larger than 10^{-10}.

  10. Acquired crossed aphasia in dextral children revisited.

    PubMed

    Marien, P; Paquier, P; Engelborghs, S; De Deyn, P P

    2001-12-01

    In contrast to the estimated low incidence of crossed aphasia in dextral adults (among 1%), crossed aphasia in children has been considered a common finding for almost a century. However, reviewing the literature on crossed aphasia in dextrals (CAD) and its related topics from 1975 onward, we encountered only 5 children in a corpus of 180 cases (2.7%). Critical analysis rendered three of the reported cases ambiguous and hence not suitable to draw potentially relevant conclusions. In this review, the neurobehavioral manifestations of the two representative childhood CAD cases are analyzed and compared with adult CAD and acquired childhood aphasia (ACA). In the light of our findings, which support the position of innate cerebral specialization for language, the long-standing controversy as to whether lateralized hemispheric specialization for language is innate or develops progressively during maturation is briefly discussed. PMID:11781052

  11. Human myeloperoxidase in innate and acquired immunity.

    PubMed

    Arnhold, Juergen; Flemmig, Joerg

    2010-08-01

    Polymorphonuclear leukocytes (PMNs) are important players in innate and acquired immunity. These cells accumulate at inflammatory sites and contribute to host defence, regulation of the inflammatory process, and also to tissue injury. One of the key components of PMNs is the heme-containing enzyme myeloperoxidase (MPO) that is stored in large amount in azurophilic granules of resting cells. Here we review the (patho)physiological role of MPO from the viewpoint of participation of PMNs in immune reactions. Myeloperoxidase is able to catalyse a wide range of one- and two-electron substrate oxidations. With special products, MPO contributes to apoptosis induction in PMNs and other cells, and, thus, to termination of inflammatory response. On the other hand, MPO released from necrotic cells promotes an inflammation by further recruitment of PMNs, and chemical modification of proteins and other tissue constituents. Myeloperoxidase is a fascinating, multifunctional, and challenging enzyme that has not yet revealed all its secrets. PMID:20399194

  12. The acquired immunodeficiency syndrome in gay men.

    PubMed

    Jaffe, H W; Hardy, A M; Morgan, W M; Darrow, W W

    1985-11-01

    The acquired immunodeficiency syndrome (AIDS) is a major health problem for gay men in the United States. About three fourths of all reported cases have occurred in this population, and the number is projected to double in the next year. In Manhattan and San Francisco, AIDS is now the leading cause of premature mortality in men aged 25 to 44 years who have never married. In a sample of a cohort of gay men enrolled in a San Francisco clinic, 2.7% of the men had the syndrome and 26% had related conditions in 1984. Antibody to human T-lymphotropic virus, type III/lymphadenopathy-associated virus was found in sera from 67% of the men, including 58% of asymptomatic men. Behavioral factors associated with an increased risk of AIDS include large numbers of sexual partners, receptive anal intercourse, and "fisting." The adoption of safer lifestyles is currently the basis of attempts to control the syndrome in gay men. PMID:2996396

  13. Guidelines for prevention of hospital acquired infections.

    PubMed

    Mehta, Yatin; Gupta, Abhinav; Todi, Subhash; Myatra, Sn; Samaddar, D P; Patil, Vijaya; Bhattacharya, Pradip Kumar; Ramasubban, Suresh

    2014-03-01

    These guidelines, written for clinicians, contains evidence-based recommendations for the prevention of hospital acquired infections Hospital acquired infections are a major cause of mortality and morbidity and provide challenge to clinicians. Measures of infection control include identifying patients at risk of nosocomial infections, observing hand hygiene, following standard precautions to reduce transmission and strategies to reduce VAP, CR-BSI, CAUTI. Environmental factors and architectural lay out also need to be emphasized upon. Infection prevention in special subsets of patients - burns patients, include identifying sources of organism, identification of organisms, isolation if required, antibiotic prophylaxis to be used selectively, early removal of necrotic tissue, prevention of tetanus, early nutrition and surveillance. Immunodeficient and Transplant recipients are at a higher risk of opportunistic infections. The post tranplant timetable is divided into three time periods for determining risk of infections. Room ventilation, cleaning and decontamination, protective clothing with care regarding food requires special consideration. Monitoring and Surveillance are prioritized depending upon the needs. Designated infection control teams should supervise the process and help in collection and compilation of data. Antibiotic Stewardship Recommendations include constituting a team, close coordination between teams, audit, formulary restriction, de-escalation, optimizing dosing, active use of information technology among other measure. The recommendations in these guidelines are intended to support, and not replace, good clinical judgment. The recommendations are rated by a letter that indicates the strength of the recommendation and a Roman numeral that indicates the quality of evidence supporting the recommendation, so that readers can ascertain how best to apply the recommendations in their practice environments. PMID:24701065

  14. Guidelines for prevention of hospital acquired infections

    PubMed Central

    Mehta, Yatin; Gupta, Abhinav; Todi, Subhash; Myatra, SN; Samaddar, D. P.; Patil, Vijaya; Bhattacharya, Pradip Kumar; Ramasubban, Suresh

    2014-01-01

    These guidelines, written for clinicians, contains evidence-based recommendations for the prevention of hospital acquired infections Hospital acquired infections are a major cause of mortality and morbidity and provide challenge to clinicians. Measures of infection control include identifying patients at risk of nosocomial infections, observing hand hygiene, following standard precautions to reduce transmission and strategies to reduce VAP, CR-BSI, CAUTI. Environmental factors and architectural lay out also need to be emphasized upon. Infection prevention in special subsets of patients - burns patients, include identifying sources of organism, identification of organisms, isolation if required, antibiotic prophylaxis to be used selectively, early removal of necrotic tissue, prevention of tetanus, early nutrition and surveillance. Immunodeficient and Transplant recipients are at a higher risk of opportunistic infections. The post tranplant timetable is divided into three time periods for determining risk of infections. Room ventilation, cleaning and decontamination, protective clothing with care regarding food requires special consideration. Monitoring and Surveillance are prioritized depending upon the needs. Designated infection control teams should supervise the process and help in collection and compilation of data. Antibiotic Stewardship Recommendations include constituting a team, close coordination between teams, audit, formulary restriction, de-escalation, optimizing dosing, active use of information technology among other measure. The recommendations in these guidelines are intended to support, and not replace, good clinical judgment. The recommendations are rated by a letter that indicates the strength of the recommendation and a Roman numeral that indicates the quality of evidence supporting the recommendation, so that readers can ascertain how best to apply the recommendations in their practice environments. PMID:24701065

  15. Infantile and acquired nystagmus in childhood.

    PubMed

    Ehrt, Oliver

    2012-11-01

    Nystagmus is an involuntary, periodic eye movement caused by a slow drift of fixation which is followed by a fast refixation saccade (jerk nystagmus) or a slow movement back to fixation (pendular nystagmus). In childhood most cases are benign forms of nystagmus: idiopathic infantile, ocular or latent nystagmus. They arise at the age of 3 months, without oscillopsia and show the absence of the physiologic opto-kinetic nystagmus. A full ophthalmologic evaluation is all that is needed in most cases: albinism, macular or optic nerve hypoplasia and congenital retinal dystrophies are the most common forms of ocular nystagmus. Idiopathic infantile nystagmus can be hereditary, the most common and best analyzed form being a mutation of the FRMD7 gene on chromosome Xq26.2. The mutation shows a mild genotype-phenotype correlation. In all female carriers the opto-kinetic nystagmus is absent and half had mild nystagmus. Latent nystagmus is part of the infantile esotropia syndrome and shows the unique feature of change of direction when the fixing eye changes: it is always beating to the side of the fixing eye. There is no cure for infantile nystagmus but therapeutic options include magnifying visual aids or eye muscle surgery at the age of 6-8 y in patients with head turn. Less than 20% of childhood nystagmus are acquired and need further neurological and imaging work-up. Alarming signs and symptoms are: onset after the age of 4 months, oscillopsia, dissociated (asymmetric) nystagmus, preserved opto-kinetic nystagmus, afferent pupillary defect, papilloedema and neurological symptoms like vertigo and nausea. The most common cause is due to pathology of the anterior optic pathway (e.g. optic nerve gliomas). It shows the same clinical feature of dissociated nystagmus as spasmus nutans but has a higher frequency as in INO. Other forms of acquired nystagmus are due to brainstem, cerebellar or metabolic diseases. PMID:22459007

  16. 50 CFR 35.5 - Commercial enterprises, roads, motor vehicles, motorized equipment, motorboats, aircraft...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...motorized equipment, motorboats, aircraft, mechanical transport, structures, and installations...motorized equipment, motorboats, aircraft, mechanical transport, structures, and installations...conditions under which motorized equipment, mechanical transport, aircraft,...

  17. 50 CFR 35.5 - Commercial enterprises, roads, motor vehicles, motorized equipment, motorboats, aircraft...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...motorized equipment, motorboats, aircraft, mechanical transport, structures, and installations...motorized equipment, motorboats, aircraft, mechanical transport, structures, and installations...conditions under which motorized equipment, mechanical transport, aircraft,...

  18. 50 CFR 35.5 - Commercial enterprises, roads, motor vehicles, motorized equipment, motorboats, aircraft...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...motorized equipment, motorboats, aircraft, mechanical transport, structures, and installations...motorized equipment, motorboats, aircraft, mechanical transport, structures, and installations...conditions under which motorized equipment, mechanical transport, aircraft,...

  19. 50 CFR 35.5 - Commercial enterprises, roads, motor vehicles, motorized equipment, motorboats, aircraft...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...motorized equipment, motorboats, aircraft, mechanical transport, structures, and installations...motorized equipment, motorboats, aircraft, mechanical transport, structures, and installations...conditions under which motorized equipment, mechanical transport, aircraft,...

  20. 50 CFR 35.5 - Commercial enterprises, roads, motor vehicles, motorized equipment, motorboats, aircraft...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...motorized equipment, motorboats, aircraft, mechanical transport, structures, and installations...motorized equipment, motorboats, aircraft, mechanical transport, structures, and installations...conditions under which motorized equipment, mechanical transport, aircraft,...

  1. Why did the acquired immune system of vertebrates evolve?

    Microsoft Academic Search

    Jens Rolff

    2007-01-01

    Rapidly expanding genomic information offers important insights into the mechanisms of acquired immunity and has fostered progress in comparative immunology. However, the question of why the acquired immune system, a trait restricted to jawed vertebrates, evolved has rarely been addressed. Here, I will examine three unique features of early vertebrate evolution, during the 50 million years when the acquired immune

  2. Dynamically timed electric motor

    NASA Technical Reports Server (NTRS)

    Casper, Ann M. (inventor)

    1994-01-01

    The invention disclosed in this document is a brushless DC motor including a housing having an end cap secured thereto. The housing encloses a rotor, a stator and a rotationally displaceable commutation board having 5 sensors secured thereon and spaced around the periphery of the rotor. An external rotational force is applied to the commutation board for displacement of the sensors to various positions whereby varying feedback signals are generated by the positioning of the sensors relative to the rotating rotor. The commutation board is secured in a fixed position in response to feedback signals indicative of optimum sensor position being determined. The rotation of the commutation board and the securing of the sensors in the desired fixed position is accomplished without requiring the removal of the 5 end cap and with the DC motor operating.

  3. Dynamically Timed Electric Motor

    NASA Technical Reports Server (NTRS)

    Casper, Ann M. (Inventor)

    1997-01-01

    A brushless DC motor including a housing having an end cap secured thereto. The housing encloses a rotor. a stator and a rotationally displaceable commutation board having sensors secured thereon and spaced around the periphery of the rotor. An external rotational force is applied to the commutation board for displacement of the sensors to various positions whereby varying feedback signals are generated by the positioning of the sensors relative to the rotating rotor. The commutation board is secured in a fixed position in response to feedback signals indicative of optimum sensor position being determined. The rotation of the commutation board and the securing of the sensors in the desired fixed position is accomplished without requiring the removal of the end cap and with the DC motor operating.

  4. Ironless armature torque motor

    NASA Technical Reports Server (NTRS)

    Fisher, R. L.

    1972-01-01

    Four iron-less armature torque motors, four Hall device position sensor assemblies, and two test fixtures were fabricated. The design approach utilized samarium cobalt permanent magnets, a large airgap, and a three-phase winding in a stationary ironless armature. Hall devices were employed to sense rotor position. An ironless armature torque motor having an outer diameter of 4.25 inches was developed to produce a torque constant of 65 ounce-inches per ampere with a resistance of 20.5 ohms. The total weight, including structural elements, was 1.58 pounds. Test results indicated that all specifications were met except for generated voltage waveform. It is recommended that investigations be made concerning the generated voltage waveform to determine if it may be improved.

  5. Alperin's Fusion Theorem and Fusion Systems David A. Craven

    E-print Network

    Craven, David A.

    Alperin's Fusion Theorem and Fusion Systems David A. Craven September 2010 Abstract This short note provides a new and straightforward proof of the original fusion theorem of Alperin, then considers so-called domestic intersections, which are special types of tame intersections that should play a role in fusion

  6. Up-Fusion: An Evolving Multimedia Decision Fusion Xiangyu Wang

    E-print Network

    Rui, Yong

    Up-Fusion: An Evolving Multimedia Decision Fusion Method Xiangyu Wang National Univ. of Singapore multimedia's nature of hav- ing multiple information sources, fusion methods are criti- cal for its data analysis and understanding. However, most of the traditional fusion methods are static with respect to time

  7. Motor neurone disease

    PubMed Central

    Shahani, Bhagwan; Davies-Jones, G. A. B.; Russell, W. Ritchie

    1971-01-01

    Physiological and biochemical studies were carried out on 16 patients with motor neurone disease (MND). It was confirmed that the peripheral nerves in cases of MND are often unusually resistant to ischaemia especially as regards the large sensory fibres. Biochemical investigations demonstrated a tendency to carbohydrate intolerance and abnormal pyruvate metabolism. When compared with other related studies in MND it seems very likely that there is a metabolic abnormality present in MND which demands further study. Images PMID:4328410

  8. Motor actuated vacuum door

    NASA Astrophysics Data System (ADS)

    Hanagud, A. V.

    1986-10-01

    Doors that allow scientific instruments to record and retrieve the observed data are often required to be designed and installed as a part of sounding rocket hardware. The motor-actuated vacuum door was designed to maintain a medium vacuum of the order of 0.0001 torr or better while closed, and to provide an opening 15 inches long x 8.5 inches wide while open for cameras to image Halley's comet. When the electric motor receives the instruction to open the door through the payload battery, timer, and relay circuit, the first operation is to unlock the door. After unlatching, the torque transmitted by the motor to the main shaft through the links opens the door. A microswitch actuator, which rides on the linear motion conversion mechanism, is adjusted to trip the limit switch at the end of the travel. The process is repeated in the reverse order to close the door. 'O' rings are designed to maintain the seal. Door mechanisms similar to the one described have flown on Aerobee 17.018 and Black Brant 27.047 payloads.

  9. Motor gasolines, summer 1983

    SciTech Connect

    Shelton, E.M.

    1984-02-01

    The samples were collected from service stations throughout the country and were analyzed in the laboratories of various refiners, motor manufacturers, chemical companies, and research institutes. The analytical data for 1583 samples of motor gasoline, were submitted to the National Institute for Petroleum and Energy Research, Bartlesville, Oklahoma for study, necessary calculations, and compilation under a cooperative agreement between the National Institute for Petroleum and Energy Research (NIPER) and the American Petroleum Institute (API). They represent the products of 48 companies, large and small, which manufacture and supply gasoline. These data are tabulated by groups according to brands (unlabeled) and grades for 17 marketing districts into which the country is divided. A map included in this report, shows marketing areas, districts and sampling locations. The report also includes charts indicating the trends of selected properties of motor fuels since 1959. Sixteen octane distribution percent charts for areas 1, 2, 3, and 4 for unleaded antiknock index (R+M)/2 below 90.0, unleaded antiknock index (R+M)/2 90.0 and above, and leaded antiknock index (R+M)/2 below 93.0 grades of gasoline are presented in this report. The antiknock (octane) index (R+M)/2 averages of gasoline sold in this country were 87.5 for unleaded below 90.0, 91.4 for unleaded 90.0 and above, and 89.0 for leaded below 93.0 grades of gasoline. 16 figures, 5 tables.

  10. Multisensor data fusion for autonomous vehicle navigation in risky environments

    Microsoft Academic Search

    Gian Luca Foresti; Carlo S. Regazzoni

    2002-01-01

    This paper describes a multisensor data-fusion system for driving an autonomous earthwork vehicle operating in a sanitary landfill. The system acquires data from a set of ultrasonic sensors, a laser range finder, and several charge-coupled device cameras, and produces, as output, alarms that indicate potentially dangerous situations, e.g., the presence of fixed or mobile obstacles in the vehicle working area.

  11. Crystal structure of the Candida albicans Kar3 kinesin motor domain fused to maltose-binding protein

    SciTech Connect

    Delorme, Caroline; Joshi, Monika [Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada K7L 3N6 (Canada)] [Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada K7L 3N6 (Canada); Allingham, John S., E-mail: allinghj@queensu.ca [Department of Biomedical and Molecular Sciences, Queen's University, Kingston, ON, Canada K7L 3N6 (Canada)

    2012-11-30

    Highlights: Black-Right-Pointing-Pointer The Candida albicans Kar3 motor domain structure was solved as a maltose-binding protein fusion. Black-Right-Pointing-Pointer The electrostatic surface and part of the ATPase pocket of the motor domain differs markedly from other kinesins. Black-Right-Pointing-Pointer The MBP-Kar3 interface highlights a new site for intramolecular or intermolecular interactions. -- Abstract: In the human fungal pathogen Candida albicans, the Kinesin-14 motor protein Kar3 (CaKar3) is critical for normal mitotic division, nuclear fusion during mating, and morphogenic transition from the commensal yeast form to the virulent hyphal form. As a first step towards detailed characterization of this motor of potential medical significance, we have crystallized and determined the X-ray structure of the motor domain of CaKar3 as a maltose-binding protein (MBP) fusion. The structure shows strong conservation of overall motor domain topology to other Kar3 kinesins, but with some prominent differences in one of the motifs that compose the nucleotide-binding pocket and the surface charge distribution. The MBP and Kar3 modules are arranged such that MBP interacts with the Kar3 motor domain core at the same site where the neck linker of conventional kinesins docks during the 'ATP state' of the mechanochemical cycle. This site differs from the Kar3 neck-core interface in the recent structure of the ScKar3Vik1 heterodimer. The position of MBP is also completely distinct from the Vik1 subunit in this complex. This may suggest that the site of MBP interaction on the CaKar3 motor domain provides an interface for the neck, or perhaps a partner subunit, at an intermediate state of its motile cycle that has not yet been observed for Kinesin-14 motors.

  12. Fusion Ignition Research Experiment Highlights

    E-print Network

    Fusion Ignition Research Experiment Highlights FY 2004 Fusion Ignition Research Experiment #12;Need is critically needed to advance fusion science," and recommended that: "The United States should participate in the U.S. fusion program. The scientific and technological case for adding a burning plasma experiment

  13. Network Fusion Pascal Fradet1

    E-print Network

    Paris-Sud XI, Université de

    Network Fusion Pascal Fradet1 and St´ephane Hong Tuan Ha2 1 INRIA Rh^one-Alpes 655, av. de l composition method which strives to reconcile modularity and efficiency. Our technique, network fusion fusion. Fusion allows to replace internal commu- nications by assignments and alleviates most time

  14. Rapid formation and selective stabilization of synapses for enduring motor memories

    PubMed Central

    Xu, Tonghui; Yu, Xinzhu; Perlik, Andrew J.; Tobin, Willie F.; Zweig, Jonathan A.; Tennant, Kelly; Jones, Theresa; Zuo, Yi

    2010-01-01

    Novel motor skills are learned through repetitive practice and, once acquired, persist long after training stops1,2. Earlier studies have shown that such learning induces an increase in the efficacy of synapses in the primary motor cortex, the persistence of which is associated with retention of the task3–5. However, how motor learning affects neuronal circuitry at the level of individual synapses and how long-lasting memory is structurally encoded in the intact brain remain unknown. Here we show that synaptic connections in the living mouse brain rapidly respond to motor-skill learning and permanently rewire. Training in a forelimb reaching task leads to rapid (within an hour) formation of postsynaptic dendritic spines on the output pyramidal neurons in the contralateral motor cortex. Although selective elimination of spines that existed before training gradually returns the overall spine density back to the original level, the new spines induced during learning are preferentially stabilized during subsequent training and endure long after training stops. Furthermore, we show that different motor skills are encoded by different sets of synapses. Practice of novel, but not previously learned, tasks further promotes dendritic spine formation in adulthood. Our findings reveal that rapid, but long-lasting, synaptic reorganization is closely associated with motor learning. The data also suggest that stabilized neuronal connections are the foundation of durable motor memory. PMID:19946267

  15. The Multiple Dimensions of ActionOriented Robotic Perception: Fission, Fusion, and Fashion

    E-print Network

    The Multiple Dimensions of Action­Oriented Robotic Perception: Fission, Fusion, and Fashion Ronald on perceptual processing which serves as little more than academic curiosities: i.e., so­ lutions looking of the dimensions in which perception can be utilized to support motor action in the context of time and space

  16. Fusion research at ORNL

    NASA Astrophysics Data System (ADS)

    1982-03-01

    The ORNL fusion program which includes the experimental and theoretical study of two different classes of magnetic confinement schemes is outlined. The study includes: systems with helical magnetic fields, such as the Tokamak and stellarator, and the ELMO Bumpy Torus (EBT) class of toroidally linked mirror systems; the development of technologies, including superconducting magnets, neutral atomic beam and radio frequency (RF) heating systems, fueling systems, materials, and diagnostics; the development of the environment impact of magnetic fusion; and the design of advanced demonstration fusion devices.

  17. Fusion for Space Propulsion

    NASA Technical Reports Server (NTRS)

    Thio, Y. C. Francis; Schafer, Charles (Technical Monitor)

    2001-01-01

    There is little doubt that humans will attempt to explore and develop the solar system in this century. A large amount of energy will be required for accomplishing this. The need for fusion propulsion is discussed. For a propulsion system, there are three important thermodynamical attributes: (1) The absolute amount of energy available, (2) the propellant exhaust velocity, and (3) the jet power per unit mass of the propulsion system (specific power). For human exploration and development of the solar system, propellant exhaust velocity in excess of 100 km/s and specific power in excess of 10 kW/kg are required. Chemical combustion can produce exhaust velocity up to about 5 km/s. Nuclear fission processes typically result in producing energy in the form of heat that needs to be manipulated at temperatures limited by materials to about 2,800 K. Using the energy to heat a hydrogen propellant increases the exhaust velocity by only a factor of about two. Alternatively the energy can be converted into electricity which is then used to accelerate particles to high exhaust velocity. The necessary power conversion and conditioning equipment, however, increases the mass of the propulsion system for the same jet power by more than two orders of magnitude over chemical system, thus greatly limits the thrust-to-weight ratio attainable. The principal advantage of the fission process is that its development is relatively mature and is available right now. If fusion can be developed, fusion appears to have the best of all worlds in terms of propulsion - it can provide the absolute amount, the propellant exhaust velocity, and the high specific jet power. An intermediate step towards pure fusion propulsion is a bimodal system in which a fission reactor is used to provide some of the energy to drive a fusion propulsion unit. The technical issues related to fusion for space propulsion are discussed. The technical priorities for developing and applying fusion for propulsion are somewhat different from those for terrestrial electrical power generation. Thus fusion schemes that are initially attractive for electrical power generation might not necessarily be attractive also for propulsion and vice versa, though the underlying fusion science and engineering enjoy much overlap. Parallel efforts to develop these qualitatively differently fusion schemes for the two applications could benefit greatly from each other due to the synergy in the underlying physics and engineering. Pulsed approaches to fusion have not been explored to the same degree as steady-state or long-pulse approaches to fusion in the fusion power research program. The concerns early on were several. One was that the pulsed power components might not have the service lifetimes meeting the requirements of a practical power generating plant. Another was that, for many pulsed fusion schemes, it was not clear whether the destruction of hardware per pulse could be minimized or eliminated or recycled to such an extent as to make economical electrical power generation feasible, Significant development of the underlying pulsed power component technologies have occurred in the last two decades because of defense and other energy requirements. The state of development of the pulsed power technologies are sufficiently advanced now to make it compelling to visit or re-visit pulsed fusion approaches for application to propulsion where the cost of energy is not so demanding a factor as in the case of terrestrial power application. For propulsion application, the overall mass of the fusion system is the critical factor. Producing fusion reactions require extreme states of matter. Conceptually, these extreme states of matter are more readily realizable in the pulsed states, at least within appropriate bounds, than in the steady states. Significant saving in system mass may result in such systems. Magnetic fields are effective in confining plasma energy, whereas inertial compression is an effective way of heating and containing the plasma. Intensive research in developing magnetic energy containme

  18. Somatosensory Plasticity and Motor Learning

    PubMed Central

    Ostry, David J.; Darainy, Mohammad; Mattar, Andrew A.G.; Wong, Jeremy; Gribble, Paul L.

    2010-01-01

    Motor learning is dependent upon plasticity in motor areas of the brain, but does it occur in isolation or does it also result in changes to sensory systems? We examined changes to somatosensory function that occur in conjunction with motor learning. We found that even after periods of training as brief as 10 minutes, sensed limb position was altered and the perceptual change persisted for 24 hours. The perceptual change was reflected in subsequent movements; limb movements following learning deviated from the pre-learning trajectory by an amount that was not different in magnitude and in the same direction as the perceptual shift. Crucially, the perceptual change was dependent upon motor learning. When the limb was displaced passively such that subjects experienced similar kinematics but without learning, no sensory change was observed. The findings indicate that motor learning affects not only motor areas of the brain but changes sensory function as well. PMID:20392960

  19. The complex pathophysiology of acquired aplastic anaemia.

    PubMed

    Zeng, Y; Katsanis, E

    2015-06-01

    Immune-mediated destruction of haematopoietic stem/progenitor cells (HSPCs) plays a central role in the pathophysiology of acquired aplastic anaemia (aAA). Dysregulated CD8(+) cytotoxic T cells, CD4(+) T cells including T helper type 1 (Th1), Th2, regulatory T cells and Th17 cells, natural killer (NK) cells and NK T cells, along with the abnormal production of cytokines including interferon (IFN)-?, tumour necrosis factor (TNF)-? and transforming growth factor (TGF)-?, induce apoptosis of HSPCs, constituting a consistent and defining feature of severe aAA. Alterations in the polymorphisms of TGF-?, IFN-? and TNF-? genes, as well as certain human leucocyte antigen (HLA) alleles, may account for the propensity to immune-mediated killing of HSPCs and/or ineffective haematopoiesis. Although the inciting autoantigens remain elusive, autoantibodies are often detected in the serum. In addition, recent studies provide genetic and molecular evidence that intrinsic and/or secondary deficits in HSPCs and bone marrow mesenchymal stem cells may underlie the development of bone marrow failure. PMID:25683099

  20. Acquiring synaesthesia: insights from training studies

    PubMed Central

    Rothen, Nicolas; Meier, Beat

    2014-01-01

    Synaesthesia denotes a condition of remarkable individual differences in experience characterized by specific additional experiences in response to normal sensory input. Synaesthesia seems to (i) run in families which suggests a genetic component, (ii) is associated with marked structural and functional neural differences, and (iii) is usually reported to exist from early childhood. Hence, synaesthesia is generally regarded as a congenital phenomenon. However, most synaesthetic experiences are triggered by cultural artifacts (e.g., letters, musical sounds). Evidence exists to suggest that synaesthetic experiences are triggered by the conceptual representation of their inducer stimuli. Cases were identified for which the specific synaesthetic associations are related to prior experiences and large scale studies show that grapheme-color associations in synaesthesia are not completely random. Hence, a learning component is inherently involved in the development of specific synaesthetic associations. Researchers have hypothesized that associative learning is the critical mechanism. Recently, it has become of scientific and public interest if synaesthetic experiences may be acquired by means of associative training procedures and whether the gains of these trainings are associated with similar cognitive benefits as genuine synaesthetic experiences. In order to shed light on these issues and inform synaesthesia researchers and the general interested public alike, we provide a comprehensive literature review on developmental aspects of synaesthesia and specific training procedures in non-synaesthetes. Under the light of a clear working definition of synaesthesia, we come to the conclusion that synaesthesia can potentially be learned by the appropriate training. PMID:24624072

  1. Mycobacterial disease, immunosuppression, and acquired immunodeficiency syndrome.

    PubMed Central

    Collins, F M

    1989-01-01

    The mycobacteria are an important group of acid-fast pathogens ranging from obligate intracellular parasites such as Mycobacterium leprae to environmental species such as M. gordonae and M. fortuitum. The latter may behave as opportunistic human pathogens if the host defenses have been depleted in some manner. The number and severity of such infections have increased markedly with the emergence of the acquired immunodeficiency syndrome (AIDS) epidemic. These nontuberculous mycobacteria tend to be less virulent for humans than M. tuberculosis, usually giving rise to self-limiting infections involving the cervical and mesenteric lymph nodes of young children. However, the more virulent serovars of M. avium complex can colonize the bronchial and intestinal mucosal surfaces of healthy individuals, becoming virtual members of the commensal gut microflora and thus giving rise to low levels of skin hypersensitivity to tuberculins prepared from M. avium and M. intracellulare. Systemic disease develops when the normal T-cell-mediated defenses become depleted as a result of old age, cancer chemotherapy, or infection with human immunodeficiency virus. As many as 50% of human immunodeficiency virus antibody-positive individuals develop mycobacterial infections at some time during their disease. Most isolates of M. avium complex from AIDS patients fall into serotypes 4 and 8. The presence of these drug-resistant mycobacteria in the lungs of the AIDS patient makes their effective clinical treatment virtually impossible. More effective chemotherapeutic, prophylactic, and immunotherapeutic reagents are urgently needed to treat this rapidly increasing patient population. PMID:2680057

  2. Free radicals mediate systemic acquired resistance.

    PubMed

    Wang, Caixia; El-Shetehy, Mohamed; Shine, M B; Yu, Keshun; Navarre, Duroy; Wendehenne, David; Kachroo, Aardra; Kachroo, Pradeep

    2014-04-24

    Systemic acquired resistance (SAR) is a form of resistance that protects plants against a broad spectrum of secondary infections. However, exploiting SAR for the protection of agriculturally important plants warrants a thorough investigation of the mutual interrelationships among the various signals that mediate SAR. Here, we show that nitric oxide (NO) and reactive oxygen species (ROS) serve as inducers of SAR in a concentration-dependent manner. Thus, genetic mutations that either inhibit NO/ROS production or increase NO accumulation (e.g., a mutation in S-nitrosoglutathione reductase [GSNOR]) abrogate SAR. Different ROS function additively to generate the fatty-acid-derived azelaic acid (AzA), which in turn induces production of the SAR inducer glycerol-3-phosphate (G3P). Notably, this NO/ROS?AzA?G3P-induced signaling functions in parallel with salicylic acid-derived signaling. We propose that the parallel operation of NO/ROS and SA pathways facilitates coordinated regulation in order to ensure optimal induction of SAR. PMID:24726369

  3. Acquired Hemophilia A Successfully Treated with Rituximab

    PubMed Central

    D’Arena, Giovanni; Grandone, Elvira; Di Minno, Matteo Nicola Dario; Musto, Pellegrino; Di Minno, Giovanni

    2015-01-01

    Acquired hemophilia A (AHA) is a rare bleeding disorder due to the development of specific autoantibodies against factor VIII. The anti-CD20 monoclonal antibody Rituximab has been proven to be effective in obtaining a long-term suppression of inhibitors of AHA, besides other immunosuppressive standard treatments. Here we describe a case of idiopathic AHA in a 60-year old man successfully treated with rituximab. He showed a complete clinical response with a normalization of clotting parameters after 5 weekly courses of rituximab given at a dose of 375 mg/sqm., but after stopping rituximab, an initial worsening of coagulation parameters induced the addition of 3 further courses. At present, the patient is in complete clinical and hematological remission after 200 days. This case confirms that Rituximab may be a safe and useful tool to treat AHA and, a prolonged administration can overcome the initial resistance. However, the precise position of this drug in the therapeutic strategy (first or second-line, alone or in combination with other drugs) remains to be established and warrants further investigation. PMID:25745551

  4. Community-acquired Pneumonia and its Complications.

    PubMed

    Qin, Qiang; Shen, Kun-Ling

    2015-08-01

    Community-acquired pneumonia (CAP) remains a major cause of morbidity and mortality worldwide in developing and developed countries, and its incidence is highest among children less than 5-y-old. Over the last five years, several international and local guidelines have been updated with new evidence concerning the epidemiology, etiology, pathogenesis, treatment and prevention of pediatric CAP, but there are still several major problems that need to be standardised. The aim of this review is to consider the available data concerning the termination, epidemiology, microbiology and pathogenesis, clinical features, diagnosis and differential diagnosis, treatment, and complications of pediatric CAP. There still are many unanswered questions concerning the management of CAP, including its definition, the difficulty to identify its etiological agents, the emergence of drug, and the lack of introduction of vaccines against respiratory pathogens in developing countries. More research is required in various areas (including therapy of atypical agents), and further efforts are needed to increase vaccination in order to reduce the incidence of the disease. PMID:25976616

  5. Development of Ulta-Efficient Electric Motors

    Microsoft Academic Search

    B. Shoykhet; R. Schiferl; R. Duckworth; C. M. Rey; S. W. Schwenterly; M. J. Gouge

    2008-01-01

    Electric motors utilize a large amount of electrical energy in utility and industrial applications. Electric motors constructed with high temperature superconducting (HTS) materials have the potential to dramatically reduce electric motor size and losses. HTS motors are best suited for large motor applications at ratings above 1000 horsepower (hp), where the energy savings from the efficiency improvement can overcome the

  6. Servo motor selection criterion for mechatronic applications

    Microsoft Academic Search

    Herman J. Van de Straete; Pascal Degezelle; J. De Schutter; R. J. M. Belmans

    1998-01-01

    Modern mechatronic applications often involve complex motions, resulting in highly dynamic motor loads. The selection of an appropriate motor is based on the characteristics of the load, besides other technical, as well as economic, considerations. However, motor characteristics, such as rotor inertia, affect the motor load, which complicates the analysis. The selection criterion presented in this paper separates the motor

  7. Simulation studies of Brownian motors

    NASA Astrophysics Data System (ADS)

    Kuwada, Nathan James

    Biological molecular motors achieve directed motion and perform work in an environment dominated by thermal noise and in most cases incorporate thermally driven motion into the motor process. Inspired by bio-molecular motors, many other motor systems that incorporate thermal motion have been developed and studied. These motors are broadly referred to as Brownian motors. This dissertation presents simulation studies of two particular Brownian motors, the feedback-controlled flashing ratchet and an artificial molecular motor concept, the results of which not only drive experimental considerations but also illuminate physical behaviors that may be applicable to other Brownian motors. A flashing ratchet rectifies the motion of diffusive particles using a time dependent, asymmetric potential energy landscape, and the transport speed of the ratchet can be increased if information about the particle distribution is incorporated as feedback in the time dependency of the landscape. Using a Langevin Dynamics simulation, we compare two implementations of feedback control, a discrete algorithm and a continuous algorithm, and find that the discrete algorithm is less sensitive to fluctuations in the particle distribution. We also model an experimental system with time delay and find that the continuous algorithm can be improved by adjusting the feedback criteria to react to the expected state of the system after the delay time rather than the real-time state of the system. Motivated by the desire to understand bio-molecular linear stepping motors, we present a bottom-up approach of designing an artificial molecular motor. We develop a coarse-grained Molecular Dynamics model that is used to understand physical contributions to the diffusive stepping time of the motor and discover that partially reducing the diffusional space from 3D to 1D can dramatically increase motor speed. We also develop a stochastic model based on the classical Master equation for the system and explore the sensitivity of the motor to currently undetermined experimental parameters. We find that a reduced diffusional stepping time is critical to maintain motor attachment for many successive steps and explore an experimental design effect that leads to motor misstepping.

  8. A linear induction motor conveyer 

    E-print Network

    Solinsky, Kenneth Sheldon

    1973-01-01

    , for their assistance in setting up f'acilities for testing the linear motor, and for their hoLp in clarifying some poLnts regardIng the mo- toz ' s operation. The author is most grateful to hi wife, Grace. Not only did she do all the typing for the thesis, 'but... of the Motor VI. LINEAR MOTOR CONSTRUCTION VII. LINEAR MOTOR PERFORMANCE Evaluation of Graphs Page iii 3X 7 8 13 23 23 32 51 55 60 62 67 69 69 71 86 91 ChaPter VIII. COST AND OTHER CONSIDERATIONS INVOLVED IN TRE SELECTION OF A LINEAR...

  9. Fusion-breeder program

    SciTech Connect

    Moir, R.W.

    1982-11-19

    The various approaches to a combined fusion-fission reactor for the purpose of breeding /sup 239/Pu and /sup 233/U are described. Design aspects and cost estimates for fuel production and electricity generation are discussed. (MOW)

  10. Fusion: The Hydrogen Bomb

    NSDL National Science Digital Library

    2004-02-20

    Just after World War II, nuclear scientists turned their attention from fission to fusion. This video segment adapted from AMERICAN EXPERIENCE looks at the beginnings of thermonuclear power generation.

  11. Fusion Energy Sciences

    NSDL National Science Digital Library

    1969-12-31

    As part of the US Department of Energy, the Office of Science contains the Fusion Energy Sciences program, whose mission is to advance plasma science and fusion science technology. The program "supports research to understand the physics of plasmas; to identify and explore innovative and cost-effective development paths to fusion energy; and as a partner in international efforts, to advance the science and technology of energy-producing plasmas." Visitors to the Fusion Energy Sciences Web site will find current news related to the program, a program highlights document, several informative published papers, additional links, and more. If you're interested in energy, physics, or other related sciences, you'll definitely enjoy learning about the cutting edge science being undertaken within the department.

  12. On cold fusion

    Microsoft Academic Search

    Spinrad

    1990-01-01

    This paper argues that a high negative voltage on a metal into which deuterium is soaked might enhance fusion reactions. The author discusses how this may have been the way Fleischmann and Pons achieved their results.

  13. Spectral Label Fusion

    E-print Network

    Wachinger, Christian

    We present a new segmentation approach that combines the strengths of label fusion and spectral clustering. The result is an atlas-based segmentation method guided by contour and texture cues in the test image. This offers ...

  14. Cold nuclear fusion

    SciTech Connect

    Tsyganov, E. N., E-mail: edward.tsyganov@utsouthwestern.edu [University of Texas Southwestern Medical Center at Dallas (United States)

    2012-02-15

    Recent accelerator experiments on fusion of various elements have clearly demonstrated that the effective cross-sections of these reactions depend on what material the target particle is placed in. In these experiments, there was a significant increase in the probability of interaction when target nuclei are imbedded in a conducting crystal or are a part of it. These experiments open a new perspective on the problem of so-called cold nuclear fusion.

  15. Building fusion systems

    Microsoft Academic Search

    E. Shahbazian

    2002-01-01

    Information and data fusion is a discipline that provides the methods and techniques to build observe-orient-decide-act (OODA) capabilities for various applications. There are many ways in which these methods and techniques can be chosen to provide capabilities in each phase of the OODA decision-making cycle, and there are different fusion architectures, i.e., ways these methods and techniques can be applied,

  16. Fusion product spectra

    SciTech Connect

    Talley, T.L.; Hale, G.M.

    1988-01-01

    Accurate fusion product data is required for most fusion plasma simulations. The energy broadening of reaction products is demonstrated to be more complicated than the usual Gaussian broadening. The accurate integrals are performed to obtain , , and for all binary reactions in the four- and five-nucleon systems. Reaction cross sections were developed using R-Matrix models that include most recent measurements.

  17. Still Flying Fusion Edition

    E-print Network

    2013-11-27

    . ; The Fox Television Broadcasting Company ; 20th Century Fox Ltd. ; Fox Home Entertainment or Universal Pictures All rights are reserved and owned by the copyright holders as appropriate. Welcome to this very special Fusion Edition of Still.... This abridged edition is available only at Fusion, Issue Two will be available soon, complete with an Adam Baldwin interview! If you wish to subscribe (for free) please email stillflying@bitwiser.com with the subject heading "Subscribe" and you...

  18. Fusion ignition research experiment

    SciTech Connect

    Dale Meade

    2000-07-18

    Understanding the properties of high gain (alpha-dominated) fusion plasmas in an advanced toroidal configuration is the largest remaining open issue that must be addressed to provide the scientific foundation for an attractive magnetic fusion reactor. The critical parts of this science can be obtained in a compact high field tokamak which is also likely to provide the fastest and least expensive path to understanding alpha-dominated plasmas in advanced toroidal systems.

  19. Bearingless switched reluctance motor

    NASA Technical Reports Server (NTRS)

    Morrison, Carlos R. (Inventor)

    2004-01-01

    A switched reluctance motor has a stator with a first set of poles directed toward levitating a rotor horizontally within the stator. A disc shaped portion of a hybrid rotor is affected by the change in flux relative to the current provided at these levitation poles. A processor senses the position of the rotor and changes the flux to move the rotor toward center of the stator. A second set of poles of the stator are utilized to impart torque upon a second portion of the rotor. These second set of poles are driven in a traditional switched reluctance manner by the processor.

  20. Light-driven motor

    NASA Astrophysics Data System (ADS)

    Okamura, Hideki

    2011-02-01

    A light-driven motor operated by a single source of light is demonstrated for the first time. The device utilizes a NiTi shape memory alloy (SMA) wire initially trained straight shape. The SMA wire was formed in a loop and put around two wheels. In the experiment a steady and continuous rotation was achieved with a bundled loop of 0.3-mm diameter wire. The rotational speed was proportional to the incident light power and 60 rpm was obtained at 3.6 W of light power. The experimental result was consistent with the theory.

  1. ITER Fusion Energy

    ScienceCinema

    Dr. Norbert Holtkamp

    2010-01-08

    ITER (in Latin ?the way?) is designed to demonstrate the scientific and technological feasibility of fusion energy. Fusion is the process by which two light atomic nuclei combine to form a heavier over one and thus release energy. In the fusion process two isotopes of hydrogen ? deuterium and tritium ? fuse together to form a helium atom and a neutron. Thus fusion could provide large scale energy production without greenhouse effects; essentially limitless fuel would be available all over the world. The principal goals of ITER are to generate 500 megawatts of fusion power for periods of 300 to 500 seconds with a fusion power multiplication factor, Q, of at least 10. Q ? 10 (input power 50 MW / output power 500 MW). The ITER Organization was officially established in Cadarache, France, on 24 October 2007. The seven members engaged in the project ? China, the European Union, India, Japan, Korea, Russia and the United States ? represent more than half the world?s population. The costs for ITER are shared by the seven members. The cost for the construction will be approximately 5.5 billion Euros, a similar amount is foreseen for the twenty-year phase of operation and the subsequent decommissioning.

  2. Magnetized Target Fusion

    NASA Technical Reports Server (NTRS)

    Griffin, Steven T.

    2002-01-01

    Magnetized target fusion (MTF) is under consideration as a means of building a low mass, high specific impulse, and high thrust propulsion system for interplanetary travel. This unique combination is the result of the generation of a high temperature plasma by the nuclear fusion process. This plasma can then be deflected by magnetic fields to provide thrust. Fusion is initiated by a small traction of the energy generated in the magnetic coils due to the plasma's compression of the magnetic field. The power gain from a fusion reaction is such that inefficiencies due to thermal neutrons and coil losses can be overcome. Since the fusion reaction products are directly used for propulsion and the power to initiate the reaction is directly obtained from the thrust generation, no massive power supply for energy conversion is required. The result should be a low engine mass, high specific impulse and high thrust system. The key is to successfully initiate fusion as a proof-of-principle for this application. Currently MSFC is implementing MTF proof-of-principle experiments. This involves many technical details and ancillary investigations. Of these, selected pertinent issues include the properties, orientation and timing of the plasma guns and the convergence and interface development of the "pusher" plasma. Computer simulations of the target plasma's behavior under compression and the convergence and mixing of the gun plasma are under investigation. This work is to focus on the gun characterization and development as it relates to plasma initiation and repeatability.

  3. 27. View, looking north, of motor house; the electric motor ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. View, looking north, of motor house; the electric motor and electric-powered winch are housed in section of building to the left. Photo by Jet Lowe, HAER, 1989. - Puget Sound Power & Light Company, White River Hydroelectric Project, 600 North River Avenue, Dieringer, Pierce County, WA

  4. Next-generation systemic acquired resistance.

    PubMed

    Luna, Estrella; Bruce, Toby J A; Roberts, Michael R; Flors, Victor; Ton, Jurriaan

    2012-02-01

    Systemic acquired resistance (SAR) is a plant immune response to pathogen attack. Recent evidence suggests that plant immunity involves regulation by chromatin remodeling and DNA methylation. We investigated whether SAR can be inherited epigenetically following disease pressure by Pseudomonas syringae pv tomato DC3000 (PstDC3000). Compared to progeny from control-treated Arabidopsis (Arabidopsis thaliana; C(1)), progeny from PstDC3000-inoculated Arabidopsis (P(1)) were primed to activate salicylic acid (SA)-inducible defense genes and were more resistant to the (hemi)biotrophic pathogens Hyaloperonospora arabidopsidis and PstDC3000. This transgenerational SAR was sustained over one stress-free generation, indicating an epigenetic basis of the phenomenon. Furthermore, P(1) progeny displayed reduced responsiveness of jasmonic acid (JA)-inducible genes and enhanced susceptibility to the necrotrophic fungus Alternaria brassicicola. This shift in SA- and JA-dependent gene responsiveness was not associated with changes in corresponding hormone levels. Instead, chromatin immunoprecipitation analyses revealed that SA-inducible promoters of PATHOGENESIS-RELATED GENE1, WRKY6, and WRKY53 in P(1) plants are enriched with acetylated histone H3 at lysine 9, a chromatin mark associated with a permissive state of transcription. Conversely, the JA-inducible promoter of PLANT DEFENSIN1.2 showed increased H3 triple methylation at lysine 27, a mark related to repressed gene transcription. P(1) progeny from the defense regulatory mutant non expressor of PR1 (npr1)-1 failed to develop transgenerational defense phenotypes, demonstrating a critical role for NPR1 in expression of transgenerational SAR. Furthermore, the drm1drm2cmt3 mutant that is affected in non-CpG DNA methylation mimicked the transgenerational SAR phenotype. Since PstDC3000 induces DNA hypomethylation in Arabidopsis, our results suggest that transgenerational SAR is transmitted by hypomethylated genes that direct priming of SA-dependent defenses in the following generations. PMID:22147520

  5. System and method for motor fault detection using stator current noise cancellation

    DOEpatents

    Zhou, Wei (Los Angeles, CA); Lu, Bin (Kenosha, WI); Nowak, Michael P. (Menomonee Falls, WI); Dimino, Steven A. (Wauwatosa, WI)

    2010-12-07

    A system and method for detecting incipient mechanical motor faults by way of current noise cancellation is disclosed. The system includes a controller configured to detect indicia of incipient mechanical motor faults. The controller further includes a processor programmed to receive a baseline set of current data from an operating motor and define a noise component in the baseline set of current data. The processor is also programmed to acquire at least on additional set of real-time operating current data from the motor during operation, redefine the noise component present in each additional set of real-time operating current data, and remove the noise component from the operating current data in real-time to isolate any fault components present in the operating current data. The processor is then programmed to generate a fault index for the operating current data based on any isolated fault components.

  6. MFN2 couples glutamate excitotoxicity and mitochondrial dysfunction in motor neurons.

    PubMed

    Wang, Wenzhang; Zhang, Fan; Li, Li; Tang, Fangqiang; Siedlak, Sandra L; Fujioka, Hisashi; Liu, Yingchao; Su, Bo; Pi, Yan; Wang, Xinglong

    2015-01-01

    Mitochondrial dysfunction plays a central role in glutamate-evoked neuronal excitotoxicity, and mitochondrial fission/fusion dynamics are essential for mitochondrial morphology and function. Here, we establish a novel mechanistic linker among glutamate excitotoxicity, mitochondrial dynamics, and mitochondrial dysfunction in spinal cord motor neurons. Ca(2+)-dependent activation of the cysteine protease calpain in response to glutamate results in the degradation of a key mitochondrial outer membrane fusion regulator, mitofusin 2 (MFN2), and leads to MFN2-mediated mitochondrial fragmentation preceding glutamate-induced neuronal death. MFN2 deficiency impairs mitochondrial function, induces motor neuronal death, and renders motor neurons vulnerable to glutamate excitotoxicity. Conversely, MFN2 overexpression blocks glutamate-induced mitochondrial fragmentation, mitochondrial dysfunction, and/or neuronal death in spinal cord motor neurons both in vitro and in mice. The inhibition of calpain activation also alleviates glutamate-induced excitotoxicity of mitochondria and neurons. Overall, these results suggest that glutamate excitotoxicity causes mitochondrial dysfunction by impairing mitochondrial dynamics via calpain-mediated MFN2 degradation in motor neurons and thus present a molecular mechanism coupling glutamate excitotoxicity and mitochondrial dysfunction. PMID:25416777

  7. Heritability of motor skill.

    PubMed

    Williams, L R; Gross, J B

    1980-01-01

    A total of 22 monozygotic (MZ) and 41 dizygotic (DZ) twin pairs were given 72 trials on a stabilometer balance task over six days to study the extent of the genetic contribution to learning and performance of a gross motor skill. The expectations that interindividual differences would be less for the MZ than for the DZ twins and that intraindividual variability would not be different between the two groups were supported. Intraclass correlations were used to provide estimates for the proportions of total phenotypic variance accounted for by heritability (h2), systematic environmental variance (E2), and nonsystematic environmental effects (e2). Heritability was found to be low during the early stages of learning, before it increased to stabilize at approximately 65% for the remaining practice. E2 was highest during these early stages (24%), then declined quickly to stabilize at half that level. Error variance (e2) constituted the remaining variance. Learning profiles of the twin pairs were also analyzed, with a greater intrapair resemblance being found for the MZ twins. The present findings indicate that, for gross motor skills, there is considerable potential for influencing both the levels of performance (and learning) and the differences between individuals by judicious use of systematic environmental effects. PMID:7196128

  8. Developing a Motor Management Policy at BASF 

    E-print Network

    Zickefoose, B.; Theising, T. R.

    2001-01-01

    In early 1998 Thomas R. Theising, BASF Corporate Engineering initiated the formation of a motor management team. The goal of the team was to develop a Motor Management Guideline to better manage the purchase and repair of motors used throughout...

  9. Industrial motor repair in the United States

    SciTech Connect

    Schueler, V.; Leistner, P.; Douglass, J.

    1994-09-01

    This report characterizes the motor repair industry in the United States; summarizes current motor repair and testing practice; and identifies barriers to energy motor repair practice and recommends strategies for overcoming those barriers.

  10. [Cerebrovascular hemorrhage associated with acquired cytomegalovirus infection in an infant].

    PubMed

    Muñoz, Nelson; Pinzón, Hernando; Vizcaíno, Hugo; Moneriz, Carlos

    2014-01-01

    Cytomegalovirus is the most frequent causative agent of perinatal infection and a major cause of acquired viral infections. This case report aims to show the broad clinical spectrum of the presentation of cytomegalovirus infection. The correct classification of congenital or acquired infection and its prompt treatment can prevent complications and sequelae in severe cases. We report the case of an infant with acquired cytomegalovirus infection, which presented an unusual feature of cerebral hemorrhage. The patient was treated with ganciclovir, with a favorable evolution of the clinical symptoms. Cytomegalovirus infection is common in children, both in its congenital and acquired forms. Acquired infection, as portrayed in this case, is mainly characterized by hematological compromise given by the marked thrombocytopenia, which may rarely result in cases of bleeding in the central nervous system. In this patient, no important clinical implications occurred. In addition, most of the acquired infections are self-limited and require no treatment. PMID:25504240

  11. Fusion after minimally disruptive anterior lumbar interbody fusion: Analysis of extreme lateral interbody fusion by computed tomography

    Microsoft Academic Search

    W. B. Rodgers; Edward J. Gerber; Jamie R. Patterson

    2010-01-01

    BackgroundLess invasive fusion approaches, such as extreme lateral interbody fusion (XLIF), have proliferated, but few reports have critically assessed fusion rates. To date, no studies have reported computed tomography (CT) documented fusion rates following XLIF.

  12. Community-Acquired Methicillin-Resistant Staphylococcus aureus, Finland

    Microsoft Academic Search

    Saara Salmenlinna; Outi Lyytikäinen; Jaana Vuopio-Varkila

    2002-01-01

    Methicillin-resistant Staphylococcus aureus (MRSA) is no longer only hospital acquired. MRSA is defined as community acquired if the MRSA-positive specimen was obtained outside hospital settings or within 2 days of hospital admission, and if it was from a person who had not been hospitalized within 2 years before the date of MRSA isolation. To estimate the proportion of community-acquired MRSA,

  13. Community-acquired Stenotrophomonas maltophilia infections: a systematic review

    Microsoft Academic Search

    M. E. Falagas; A. C. Kastoris; E. K. Vouloumanou; G. Dimopoulos

    2009-01-01

    Stenotrophomonas maltophilia is a pathogen that causes infections mainly in immunocompromised patients. However, community-acquired S. maltophilia infections have been occasionally reported. The objective of this paper was to collect and evaluate the available published\\u000a data referring to community-acquired S. maltophilia infections. We searched PubMed, the Cochrane Library, and Scopus for articles providing data for patients with community-acquired\\u000a S. maltophilia infections.

  14. ASRM subscale plume deflector testing. [advanced solid rocket motor

    NASA Technical Reports Server (NTRS)

    Douglas, Freddie, III; Dawson, Michael C.; Orlin, Peter A.

    1992-01-01

    This paper reports the results of the scale model (1/22) testing of candidate refractory materials to be used as surface coatings for a solid rocket motor plume deflector structure. Five ROM tests were conducted to acquire data to support the selection, thickness determination, and placement of the materials. All data acquisition was achieved through nonintrusive methods. The tests demonstrated that little or no reductions in performance of the full-scale deflector would be experienced if the most economical materials were selected for construction.

  15. Conical Bearingless Motor/Generators

    NASA Technical Reports Server (NTRS)

    Kascak, P.; Jansen, R.; Dever, T.

    2008-01-01

    Motor/generators based on conical magnetic bearings have been invented as an improved alternative to prior such machines based, variously, on radial and/or axial magnetic bearings. Both the present and prior machines are members of the class of so-called bearingless or self bearing (in the sense of not containing mechanical bearings) rotary machines. Each motor/generator provides both a torque and force allowing it to either function as a motor and magnetic bearing or a generator and magnetic bearing concurrently. Because they are not subject to mechanical bearing wear, these machines have potentially long operational lives and can function without lubrication and over wide ranges of speed and temperature that include conditions under which lubricants would become depleted, degraded, or ineffective and mechanical bearings would fail. The figure shows three typical configurations of conical bearingless motor/generators. The main elements of each motor/generator are concentric rotor and stator portions having conically tapered surfaces facing each other across a gap. Because a conical motor/generator imposes both radial and axial magnetic forces, it acts, in effect, as a combination of an axial and a radial magnetic bearing. Therefore, only two conical motor/generators - one at each end of a rotor - are needed to effect complete magnetic leviation of the rotor, whereas previously, it was necessary to use a combination of an axial and a radial magnetic bearing at each end of the rotor to achieve complete magnetic levitation and a separate motor to provide torque.

  16. Verification of Motor Repair Quality 

    E-print Network

    Butler, K.

    1998-01-01

    Motor testing at Advanced Energy has shown that a motor that has not suffered irreparable damage as a result of failure can be repaired to perform as well as before the failure. But the only way to achieve the performance level of an energy...

  17. Perceptual Aspects of Motor Performance.

    ERIC Educational Resources Information Center

    Gallahue, David L.

    Perceptual-motor functioning is a cyclic process involving: (1) organizing incoming sensory stimuli with past or stored perceptual information; (2) making motor (internal) decisions based on the combination of sensory (present) and perceptual (past) information; (3) executing the actual movement (observable act) itself; and (4) evaluating the act…

  18. Torque control for electric motors

    NASA Technical Reports Server (NTRS)

    Bernard, C. A.

    1980-01-01

    Method for adjusting electric-motor torque output to accomodate various loads utilizes phase-lock loop to control relay connected to starting circuit. As load is imposed, motor slows down, and phase lock is lost. Phase-lock signal triggers relay to power starting coil and generate additional torque. Once phase lock is recoverd, relay restores starting circuit to its normal operating mode.

  19. Open-Ended Electric Motor

    ERIC Educational Resources Information Center

    Gould, Mauri

    1975-01-01

    Presents complete instructions for assembling an electric motor which does not require large amounts of power to operate and which is inexpensive as well as reliable. Several open-ended experiments with the motor are included as well as information for obtaining a kit of parts and instructions. (BR)

  20. Harmonic piezodrive — miniaturized servo motor

    Microsoft Academic Search

    Oliver Barth

    2000-01-01

    Miniaturised dc-motors used in servomotor applications show some disadvantages like very high speed and therefore are combined with gearsets of a high gear ratio which introduce backlash and low efficiency. This article proposed a different kind of motor principle by the combination of a harmonic drive gearbox and stack piezoactuators. The actuators replace the functionality of the wave generator generating

  1. Membrane Fusion Triggering

    PubMed Central

    Navaratnarajah, Chanakha K.; Negi, Surendra; Braun, Werner; Cattaneo, Roberto

    2012-01-01

    The measles virus (MV) fusion apparatus consists of a fusion protein and an attachment protein named hemagglutinin (H). After receptor-binding through its cuboidal head, the H-protein transmits the fusion-triggering signal through its stalk to the fusion protein. However, the structural basis of signal transmission is unclear because only structures of H-heads without their stalk have been solved. On the other hand, the entire ectodomain structure of the hemagglutinin-neuraminidase protein of another Paramyxovirus revealed a four-helix bundle stalk. To probe the structure of the 95-residue MV H-stalk we individually substituted head-proximal residues (positions 103–153) with cysteine, and biochemically and functionally characterized the resultant proteins. Our results indicate that most residues in the central segment (positions 103–117) can be cross-linked by engineered disulfide bonds, and thus may be engaged in a tetrameric structure. While covalent tetramerization disrupts fusion triggering function, disulfide bond reduction restores it in most positions except Asp-113. The next stalk segment (residues 123–138) also has high propensity to form covalent tetramers, but since these cross-links have little or no effect on function, it can conduct the fusion-triggering signal while remaining in a stabilized tetrameric configuration. This segment may act as a spacer, maintaining H-heads at an optimal height. Finally, the head-proximal segment (residues 139–154) has very limited propensity to trap tetramers, suggesting bifurcation into two flexible linkers clamped by inter-subunit covalent links formed by natural Cys-139 and Cys-154. We discuss the modular structure of the MV H-stalk in the context of membrane fusion triggering and cell entry by Paramyxoviruses. PMID:23007387

  2. The promotion of recovery through rehabilitation after acquired brain injury in children.

    PubMed

    Forsyth, Rob; Basu, Anna

    2015-01-01

    A degree of motor recovery is typically seen after acquired brain injury in children. The extent to which rehabilitation efforts can claim credit for this is disputed. Strong correlations between late impairment outcomes and early severity and impairment indices are seen both in adults and children. These correlations have been interpreted by some as evidence that recovery is largely intrinsic and that any additional rehabilitation effects are small. Such views are belied by published animal studies demonstrating the possibility of large rehabilitation effects. Animal models suggest that to achieve similar rehabilitation treatment effect sizes in clinical practice, rehabilitation 'doses' should be greater, rehabilitation efforts should start sooner, and premature accommodation of impairment should be avoided. PMID:25200439

  3. Fine-tuning motor torque

    SciTech Connect

    O`Connor, L.

    1996-01-01

    Direct-torque control, a new method of regulating the output of ac induction motors, provides a swift response to input commands. A new variable-speed ac motor drive system that responds to torque input commands 10 times faster than current state-of-the-art drives has been developed by ABB Industrial Systems Inc. in New Berlin, Wis. The new control system, called the ACS 600, provides an alternative to drive systems that use sophisticated flux vector control or more routine pulse width modulation--the primary methods of regulating the output of ac induction motors. The ACS 600 is suitable for use in single motor applications that require a standard level of performance, such as conveyors, fans, and pumps. But it will likely be more valuable in applications that require the linking of multiple motors, such as textile production, and in applications that require tight control over torque, such as cranes, elevators, and centrifuges.

  4. Fusion Power Associates -2013 Annual Meeting 1 General Fusion

    E-print Network

    Annual Meeting 2 The MTF "Solution" Recognized as: · Low cost · Practical Fixed: · First wall problem - 2013 Annual Meeting 3 General Fusion's Acoustically Driven MTF #12;Fusion Power Associates - 2013

  5. Fusion of decisions transmitted over Rayleigh fading channels in wireless sensor networks

    Microsoft Academic Search

    Ruixin Niu; Biao Chen; Pramod K. Varshney

    2006-01-01

    In this paper, we revisit the problem of fusing decisions transmitted over fading channels in a wireless sensor network. Previous development relies on instantaneous channel state information (CSI). However, acquiring channel information may be too costly for resource constrained sensor networks. In this paper, we propose a new likelihood ratio (LR)-based fusion rule which requires only the knowledge of channel

  6. Remote sensing data fusion by co-location of footprints from different sensors

    Microsoft Academic Search

    Mohammed Shokr

    2000-01-01

    A new tool for remote sensing data fusion has been developed. The footprint which corresponds to a single pixel from a coarse-resolution sensor is defined using the geographic information in the data as well as the radiometric characteristics of the sensor. It is then overlaid on a background image acquired from a fine-resolution sensor. The single radiometric parameter (or any

  7. Data acquisition and processing system at the NOVETTE laser-fusion facility

    Microsoft Academic Search

    J. M. Auerbach; J. R. Severyn; D. J. Kroepfl

    1982-01-01

    The computer hardware and software used for acquisition and processing of data from experiments at the NOVETTE laser fusion facility are described. Nearly two hundred sensors are used to measure the performance of millimeter extent targets irradiated by multi-kilojoule laser pulses. Sensor output is recorded on CAMAC based digitizers, CCD arrays, and film. CAMAC instrument outputs are acquired and collected

  8. An expanded cortical representation for hand movement after peripheral motor denervation

    PubMed Central

    Reddy, H; Bendahan, D; Lee, M; Johansen-Berg, H; Donaghy, M; Hilton-Jones, D; Matthews, P

    2002-01-01

    Objectives: Functional reorganisation of the motor or sensory cortex has been demonstrated in animals after section of mixed peripheral nerves. Here functional changes in the motor cortex specifically after peripheral motor denervation in humans are investigated. Methods: Functional MRI (fMRI) was used to study brain activation during a finger flexion-extension task in patients with a late onset, acquired pure motor neuropathy (n=6), contrasting results with those from patients with pure sensory neuropathies (n=4) or healthy controls (n=7). Results: Increases in the extent of activation in the motor cortex both ipsilateral and contralateral to the hand moved were found in the patients with motor neuropathy. The neuroanatomical localisation of the mixed contralateral sensorimotor cortex activation volume was more posterior for the patients with motor neuropathy than for the healthy controls (mean difference, 12 mm, p<0.05). The pure sensory neuropathy group by contrast showed no change in the extent of activation relative to healthy controls and a trend for more anterior primary sensorimotor cortex activation (p<0.06). To test whether the increased activation volumes found in patients with motor neuropathy were a result simply of factors such as increased effort with movement rather than the motor denervation, patients with hand weakness from inclusion body myositis (n=4) were studied while making similar hand movements. No differences in either the numbers of significantly activated voxels or in their localisation were found relative to healthy controls (n=10). Conclusions: These results provide a novel demonstration that peripheral denervation (as distinguished from factors related to weakness) leads to functional reorganisation of the sensorimotor cortex in the adult brain. This suggests that adaptive responses to motor denervation involve the central as well as the peripheral nervous system. PMID:11796770

  9. Mechanisms of Acquired Resistance to ALK Inhibitors and the Rationale for Treating ALK-positive Lung Cancer

    PubMed Central

    Isozaki, Hideko; Takigawa, Nagio; Kiura, Katsuyuki

    2015-01-01

    The discovery of an echinoderm microtubule-associated protein-like 4 (EML4)-anaplastic lymphoma kinase (ALK) fusion gene led to improved clinical outcomes in patients with lung cancer after the development of the first ALK-targeting agent, crizotinib. Some second-generation ALK tyrosine kinase inhibitors (TKIs), which might be more potent than crizotinib or effective on crizotinib-resistant patients, have been developed. Although these ALK-TKIs show an excellent response initially, most patients eventually acquire resistance. Therefore, careful consideration of the resistance mechanisms might lead to superior therapeutic strategies. Here, we summarize the history of ALK-TKIs and their underlying resistance mechanisms in both the preclinical and clinical settings. In addition, we discuss potential future treatment strategies in ALK-TKI-naïve and -resistant patients with lung cancer harboring the EML4-ALK fusion gene. PMID:25941796

  10. Study on airborne multispectral imaging fusion detection technology

    NASA Astrophysics Data System (ADS)

    Ding, Na; Gao, Jiaobo; Wang, Jun; Cheng, Juan; Gao, Meng; Gao, Fei; Fan, Zhe; Sun, Kefeng; Wu, Jun; Li, Junna; Gao, Zedong; Cheng, Gang

    2014-11-01

    The airborne multispectral imaging fusion detection technology is proposed in this paper. In this design scheme, the airborne multispectral imaging system consists of the multispectral camera, the image processing unit, and the stabilized platform. The multispectral camera can operate in the spectral region from visible to near infrared waveband (0.4-1.0um), it has four same and independent imaging channels, and sixteen different typical wavelengths to be selected based on the different typical targets and background. The related experiments were tested by the airborne multispectral imaging system. In particularly, the camouflage targets were fused and detected in the different complex environment, such as the land vegetation background, the desert hot background and underwater. In the spectral region from 0.4 um to 1.0um, the three different characteristic wave from sixteen typical spectral are selected and combined according to different backgrounds and targets. The spectral image corresponding to the three characteristic wavelengths is resisted and fused by the image processing technology in real time, and the fusion video with typical target property is outputted. In these fusion images, the contrast of target and background is greatly increased. Experimental results confirm that the airborne multispectral imaging fusion detection technology can acquire multispectral fusion image with high contrast in real time, and has the ability of detecting and identification camouflage objects from complex background to targets underwater.

  11. Challenges of nuclear fusion

    SciTech Connect

    Kunkel, W.B.

    1987-05-01

    After 30 years of research and development in many countries, the magnetic confinement fusion experiments finally seem to be getting close to the original first goal: the point of ''scientific break-even.'' Plans are being made for a generation of experiments and tests with actual controlled thermonuclear fusion conditions. Therefore, engineers and material scientists are hard at work to develop the required technology. In this paper the principal elements of a generic fusion reactor are described briefly to introduce the reader to the nature of the problems at hand. The main portion of the presentation summarizes the recent advances made in this field and discusses the major issues that still need to be addressed in regard to materials and technology for fusion power. Specific examples are the problems of the first wall and other components that come into direct contact with the plasma, where both lifetime and plasma contamination are matters of concern. Equally challenging are the demands on structural materials and on the magnetic-field coils, particularly in connection with the neutron-radiation environment of fusion reactors. Finally, the role of ceramics must be considered, both for insulators and for fuel breeding purposes. It is evident that we still have a formidable task before us, but at this point none of the problems seem to be insoluble. 17 refs., 3 figs.

  12. Control Performance of an Air Motor: Can Air Motors Replace Electric Motors?

    Microsoft Academic Search

    Shunmugham R. Pandian; F. Takemura; Yasuhiro Hayakawa; Sadao Kawamura

    1999-01-01

    Pneumatic actuators are among a variety of actuators under active study by the robotics community, for the advantages they offer over conventional electric actuators widely used in present-day robots. So far, however, only pneumatic cylinders which provide linear actuation have been mainly studied in literature. Air motors are the pneumatic counterparts of electric motors, providing rotary actuation. They have several

  13. Piezoelectric wave motor

    DOEpatents

    Yerganian, Simon Scott (Lee's Summit, MO)

    2001-07-17

    A piezoelectric motor having a stator in which piezoelectric elements are contained in slots formed in the stator transverse to the desired wave motion. When an electric field is imposed on the elements, deformation of the elements imposes a force perpendicular to the sides of the slot, deforming the stator. Appropriate frequency and phase shifting of the electric field will produce a wave in the stator and motion in a rotor. In a preferred aspect, the piezoelectric elements are configured so that deformation of the elements in direction of an imposed electric field, generally referred to as the d.sub.33 direction, is utilized to produce wave motion in the stator. In a further aspect, the elements are compressed into the slots so as to minimize tensile stresses on the elements in use.

  14. Reciprocating linear motor

    NASA Technical Reports Server (NTRS)

    Goldowsky, Michael P. (inventor)

    1987-01-01

    A reciprocating linear motor is formed with a pair of ring-shaped permanent magnets having opposite radial polarizations, held axially apart by a nonmagnetic yoke, which serves as an axially displaceable armature assembly. A pair of annularly wound coils having axial lengths which differ from the axial lengths of the permanent magnets are serially coupled together in mutual opposition and positioned with an outer cylindrical core in axial symmetry about the armature assembly. One embodiment includes a second pair of annularly wound coils serially coupled together in mutual opposition and an inner cylindrical core positioned in axial symmetry inside the armature radially opposite to the first pair of coils. Application of a potential difference across a serial connection of the two pairs of coils creates a current flow perpendicular to the magnetic field created by the armature magnets, thereby causing limited linear displacement of the magnets relative to the coils.

  15. Piezoelectric wave motor

    DOEpatents

    Yerganian, Simon Scott (Lee's Summit, MO)

    2003-02-11

    A piezoelectric motor having a stator in which piezoelectric elements are contained in slots formed in the stator transverse to the desired wave motion. When an electric field is imposed on the elements, deformation of the elements imposes a force perpendicular to the sides of the slot, deforming the stator. Appropriate frequency and phase-shifting of the electric field will produce a wave in the stator and motion in a rotor. In a preferred aspect, the piezoelectric elements are configured so that deformation of the elements in the direction of an imposed electric field, generally referred to as the d.sub.33 direction, is utilized to produce wave motion in the stator. In a further aspect, the elements are compressed into the slots so as to minimize tensile stresses on the elements in use.

  16. Stimulation of motor tracts in motor neuron disease.

    PubMed Central

    Berardelli, A; Inghilleri, M; Formisano, R; Accornero, N; Manfredi, M

    1987-01-01

    The muscle responses evoked by cortical and cervical stimulation in 11 patients with motor neuron disease were studied. The muscle potential in the abductor pollicis brevis, evoked by median nerve stimulation and the somatosensory potential evoked by wrist stimulation were also studied. In eight of 11 patients there was absence or increased central delay of the responses evoked by cortical stimulation. In four patients muscle responses on cervical stimulation and muscle action potentials on median nerve stimulation were also altered, indicating peripheral abnormalities. Somatosensory responses evoked by wrist stimulation were normal. Electrophysiological techniques are helpful in estimating the site of motor involvement in motor neuron disease. PMID:3612154

  17. Realization of Fusion Energy: An alternative fusion roadmap

    E-print Network

    Realization of Fusion Energy: An alternative fusion roadmap Farrokh Najmabadi Professor of Electrical & Computer Engineering Director, Center for Energy Research UC San Diego International Fusion Road of emerging nations, energy use is expected to grow ~ 4 fold in this century (average 1.6% annual growth rate

  18. Multisensor data fusion algorithm development

    SciTech Connect

    Yocky, D.A.; Chadwick, M.D.; Goudy, S.P.; Johnson, D.K.

    1995-12-01

    This report presents a two-year LDRD research effort into multisensor data fusion. We approached the problem by addressing the available types of data, preprocessing that data, and developing fusion algorithms using that data. The report reflects these three distinct areas. First, the possible data sets for fusion are identified. Second, automated registration techniques for imagery data are analyzed. Third, two fusion techniques are presented. The first fusion algorithm is based on the two-dimensional discrete wavelet transform. Using test images, the wavelet algorithm is compared against intensity modulation and intensity-hue-saturation image fusion algorithms that are available in commercial software. The wavelet approach outperforms the other two fusion techniques by preserving spectral/spatial information more precisely. The wavelet fusion algorithm was also applied to Landsat Thematic Mapper and SPOT panchromatic imagery data. The second algorithm is based on a linear-regression technique. We analyzed the technique using the same Landsat and SPOT data.

  19. Fusion Categories and Homotopy Theory

    E-print Network

    Etingof, Pavel I.

    We apply the yoga of classical homotopy theory to classification problems of G-extensions of fusion and braided fusion categories, where G is a finite group. Namely, we reduce such problems to classification (up to homotopy) ...

  20. Fusion reactors as a future energy source

    Microsoft Academic Search

    W. Seifritz

    1975-01-01

    A detailed update of fusion research concepts is given. Discussions are given for the following areas: (1) the magnetic confinement principle, (2) UWMAK I: conceptual design for a fusion reactor, (3) the inertial confinement principle, (4) the laser fusion power plant, (5) electron-induced fusion, (6) the long-term development potential of fusion reactors, (7) the symbiosis between fusion and fission reactors,

  1. Noninvasive brain stimulation: the potential for use in the rehabilitation of pediatric acquired brain injury.

    PubMed

    Chung, Melissa G; Lo, Warren D

    2015-04-01

    Noninvasive brain stimulation (NIBS) offers the potential to modulate neural activity and recovery after acquired brain injury. There are few studies of NIBS in children, but a survey of those studies might provide insight into the potential for NIBS to modulate motor rehabilitation, seizures, and behavior in children. We surveyed the published literature prior to July 2014 for articles pertaining to children and NIBS with a focus on case series or trials. We also reviewed selected articles involving adults to illustrate specific points where the literature in children is lacking. A limited number of articles suggest that NIBS can transiently improve motor function. The evidence for an effect on seizures is mixed. Two open-label studies reported improvement of mood in adolescents with depression. NIBS may serve as a tool for pediatric neurorehabilitation, but many gaps in our knowledge must be filled before NIBS can be adopted as a clinical intervention. To move forward, the field needs adequately powered trials that can answer these questions. Such trials will be challenging to perform, will likely require multicenter collaboration, and may need to adopt novel trial designs that have been used with rare disorders. PMID:25448248

  2. CRYOGENICS FOR FUSION

    SciTech Connect

    Dauguet, P.; Bonneton, M.; Fauve, E.; Bernhardt, J. M.; Beauvisage, J.; Andrieu, F. [Air Liquide Advanced Technology Division BP15, ZI Les Engenieres, 38360 Sassenage (France); Gistau-Baguer, G. M.; Boissin, J. C. [Consultants, Grenoble (France)

    2008-03-16

    Fusion of Hydrogen to produce energy is one of the technologies under study to meet the mankind raising need in energy and as a substitute to fossil fuels for the future. This technology is under investigation for more than 30 years already, with, for example, the former construction of the experimental reactors Tore Supra, DIII-D and JET. With the construction of ITER to start, the next step to 'fusion for energy' will be done. In these projects, an extensive use of cryogenic systems is requested. Air Liquide has been involved as cryogenic partner in most of former and presently constructed fusion reactors. In the present paper, a review of the cryogenic systems we delivered to Tore Supra, JET, IPR and KSTAR will be presented.

  3. Simulation of Fusion Plasmas

    ScienceCinema

    Chris Holland

    2010-01-08

    The upcoming ITER experiment (www.iter.org) represents the next major milestone in realizing the promise of using nuclear fusion as a commercial energy source, by moving into the ?burning plasma? regime where the dominant heat source is the internal fusion reactions. As part of its support for the ITER mission, the US fusion community is actively developing validated predictive models of the behavior of magnetically confined plasmas. In this talk, I will describe how the plasma community is using the latest high performance computing facilities to develop and refine our models of the nonlinear, multiscale plasma dynamics, and how recent advances in experimental diagnostics are allowing us to directly test and validate these models at an unprecedented level.

  4. Spherical torus fusion reactor

    DOEpatents

    Peng, Yueng-Kay M. (Oak Ridge, TN)

    1989-01-01

    A fusion reactor is provided having a near spherical-shaped plasma with a modest central opening through which straight segments of toroidal field coils extend that carry electrical current for generating a toroidal magnet plasma confinement fields. By retaining only the indispensable components inboard of the plasma torus, principally the cooled toroidal field conductors and in some cases a vacuum containment vessel wall, the fusion reactor features an exceptionally small aspect ratio (typically about 1.5), a naturally elongated plasma cross section without extensive field shaping, requires low strength magnetic containment fields, small size and high beta. These features combine to produce a spherical torus plasma in a unique physics regime which permits compact fusion at low field and modest cost.

  5. Ceramics for fusion devices

    SciTech Connect

    Clinard, F.W. Jr.

    1984-01-01

    Ceramics are required for a number of applications in fusion devices, among the most critical of which are magnetic coil insulators, windows for RF heating systems, and structural uses. Radiation effects dominate consideration of candidate materials, although good pre-irradiation properties are a requisite. Materials and components can be optimized by careful control of chemical and microstructural content, and application of brittle material design and testing techniques. Future directions for research and development should include further extension of the data base in the areas of electrical, structural, and thermal properties; establishment of a fission neutron/fusion neutron correlation including transmutation gas effects; and development of new materials tailored to meet the specific needs of fusion reactors.

  6. Acquired Epiblepharon Treated by Lateral Orbital and fat Decompression

    PubMed Central

    Almousa, Radwan; Sundar, Gangadhara

    2011-01-01

    Conventional lid surgery of acquired epiblepharon secondary to increased orbital volume can be result of under correction of the epiblepharon, because the increased orbital volume remains unaddressed. In this case report, we present a case of acquired epiblepharon, secondary to increased orbital volume, treated with orbital decompression. PMID:21572743

  7. Acquired resistance of merino sheep against Fasciola gigantica

    Microsoft Academic Search

    J. A. Roberts; S. Widjayanti; E. Estuningsih

    1996-01-01

    Merino sheep acquired resistance against Fasciola gigantica, which is contrary to previous observations of infections with F. hepatica in that breed. The acquired resistance was manifest against young adult parasites. St. Croix sheep had previously been shown\\u000a to have more resistance than European sheep against F. hepatica after primary infection; however, in F. gigantica infections in the present study there

  8. Acquired hypothyroidism due to iodine deficiency in an American child.

    PubMed

    Brooks, Merrian J; Post, Ernest M

    2014-11-01

    Acquired hypothyroidism secondary to iodine deficiency is rarely reported in iodine-replete environments. The case of a 9-year-old patient with severe acquired hypothyroidism due to iodine deficiency is presented. His deficiency occurred because of a restrictive diet used to control eosinophilic esophagitis. Hypothyroidism and iodine deficiency were quickly corrected with a kelp supplement. PMID:25003378

  9. 19 CFR 148.33 - Articles acquired abroad.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...2011-04-01 2011-04-01 false Articles acquired abroad. 148.33 Section...for Returning Residents § 148.33 Articles acquired abroad. (a) Exemption...United States (19 U.S.C. 1202), articles for his personal or household...

  10. 19 CFR 148.33 - Articles acquired abroad.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...2013-04-01 2013-04-01 false Articles acquired abroad. 148.33 Section...for Returning Residents § 148.33 Articles acquired abroad. (a) Exemption...United States (19 U.S.C. 1202), articles for his personal or household...

  11. 19 CFR 148.33 - Articles acquired abroad.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...2010-04-01 2010-04-01 false Articles acquired abroad. 148.33 Section...for Returning Residents § 148.33 Articles acquired abroad. (a) Exemption...United States (19 U.S.C. 1202), articles for his personal or household...

  12. 19 CFR 148.33 - Articles acquired abroad.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...2014-04-01 2014-04-01 false Articles acquired abroad. 148.33 Section...for Returning Residents § 148.33 Articles acquired abroad. (a) Exemption...United States (19 U.S.C. 1202), articles for his personal or household...

  13. Acquiring the Reflectance Field of a Human Face

    Microsoft Academic Search

    Paul E. Debevec; Tim Hawkins; Chris Tchou; Haarm-Pieter Duiker; Westley Sarokin; Mark Sagar

    2000-01-01

    We present a method to acquire the reflectance field of a human face and use these measurements to render the face under arbitrary changes in lighting and viewpoint. We first acquire images of the face from a small set of viewpoints under a dense sampling of incident illumination directions using a light stage. We then construct a reflectance function image

  14. 45 CFR 7.4 - Option to acquire foreign rights.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Option to acquire foreign rights. 7.4 Section 7.4 ...Welfare Department of Health and Human Services GENERAL ADMINISTRATION... Option to acquire foreign rights. In any case where it is determined that all domestic rights should be assigned to...

  15. 45 CFR 7.4 - Option to acquire foreign rights.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Option to acquire foreign rights. 7.4 Section 7.4 ...Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION... Option to acquire foreign rights. In any case where it is determined that all domestic rights should be assigned to...

  16. 45 CFR 7.4 - Option to acquire foreign rights.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Option to acquire foreign rights. 7.4 Section 7.4 ...Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION... Option to acquire foreign rights. In any case where it is determined that all domestic rights should be assigned to...

  17. Hospital-acquired legionellosis: solutions for a preventable infection

    Microsoft Academic Search

    Miguel Sabria; Victor L Yu

    2002-01-01

    Hospital-acquired Legionnaires' disease has been reported from many hospitals since the first outbreak in 1976. Although cooling towers were linked to the cases of Legionnaires' disease in the years after its discovery, potable water has been the environmental source for almost all reported hospital outbreaks. Microaspiration is the major mode of transmission in hospital-acquired Legionnaires' disease; showering is not a

  18. Building and Acquiring Resources for Biomedical Language Processing

    E-print Network

    Zweigenbaum, Pierre

    for Biomedical Text Mining LREC 2010, Valetta, 18 May 2010 Pierre Zweigenbaum, LIMSI, CNRS Acquiring Resources segmentation and labeling x x x ? x Text summarising X X X X X x Text mining X x ? x X Question-answering x x X for Medical Language 1/87 #12;Introduction Outline Pierre Zweigenbaum, LIMSI, CNRS Acquiring Resources

  19. Transanal approach in repairing acquired rectovestibular fistula in females

    Microsoft Academic Search

    Ya-Jun Chen; Ting-Chong Zhang; Jin-Zhe Zhang

    AIM: To summarize the operative experience of the transanal approach in acquired rectovestibular fistula repair. METHODS: Ninety-six cases of acquired rectovestibular fistula in young females were analyzed retrospectively. The etiology and operative procedure were discussed. Operative essential points were, the patient was laid in prone frog position, with the knees and hips flexed at 90o; the perineum was elevated; and

  20. 45 CFR 7.4 - Option to acquire foreign rights.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Option to acquire foreign rights. 7.4 Section 7.4 ...Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION... Option to acquire foreign rights. In any case where it is determined that all domestic rights should be assigned to...

  1. 45 CFR 7.4 - Option to acquire foreign rights.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Option to acquire foreign rights. 7.4 Section 7.4 ...Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION... Option to acquire foreign rights. In any case where it is determined that all domestic rights should be assigned to...

  2. 7 CFR 770.8 - Use of acquired land.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...2012-01-01 2012-01-01 false Use of acquired land. 770.8 Section 770.8 Agriculture...AGRICULTURE SPECIAL PROGRAMS INDIAN TRIBAL LAND ACQUISITION LOANS § 770.8 Use of acquired land. (a) General. Subject to §...

  3. 7 CFR 770.8 - Use of acquired land.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...2013-01-01 2013-01-01 false Use of acquired land. 770.8 Section 770.8 Agriculture...AGRICULTURE SPECIAL PROGRAMS INDIAN TRIBAL LAND ACQUISITION LOANS § 770.8 Use of acquired land. (a) General. Subject to §...

  4. 7 CFR 770.8 - Use of acquired land.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...2011-01-01 2011-01-01 false Use of acquired land. 770.8 Section 770.8 Agriculture...AGRICULTURE SPECIAL PROGRAMS INDIAN TRIBAL LAND ACQUISITION LOANS § 770.8 Use of acquired land. (a) General. Subject to §...

  5. 7 CFR 770.8 - Use of acquired land.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...2010-01-01 2010-01-01 false Use of acquired land. 770.8 Section 770.8 Agriculture...AGRICULTURE SPECIAL PROGRAMS INDIAN TRIBAL LAND ACQUISITION LOANS § 770.8 Use of acquired land. (a) General. Subject to §...

  6. 7 CFR 770.8 - Use of acquired land.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...2014-01-01 2014-01-01 false Use of acquired land. 770.8 Section 770.8 Agriculture...AGRICULTURE SPECIAL PROGRAMS INDIAN TRIBAL LAND ACQUISITION LOANS § 770.8 Use of acquired land. (a) General. Subject to §...

  7. Submersible canned motor mixer pump

    DOEpatents

    Guardiani, Richard F. (Ohio Township, PA); Pollick, Richard D. (Sarver, PA)

    1997-01-01

    A mixer pump used in a waste tank for mobilizing high-level radioactive liquid waste having a column assembly containing power cables, a motor housing with electric motor means which includes a stator can of a stator assembly and a rotor can of a rotor assembly, and an impeller assembly with an impeller connected to a shaft of the rotor assembly. The column assembly locates the motor housing with the electric motor means adjacent to the impeller which creates an hydraulic head, and which forces the liquid waste into the motor housing to cool the electric motor means and to lubricate radial and thrust bearing assemblies. Hard-on-hard bearing surfaces of the bearing assemblies and a ring assembly between the impeller and electric motor means act to grind down large particles in the liquid waste flow. These larger particles are received in slots in the static bearing members of the radial bearing assemblies. Only solid waste particles smaller than the clearances in the system can pass therethrough, thereby resisting damage to and the interruption of the operation of the mixer pump.

  8. Submersible canned motor transfer pump

    DOEpatents

    Guardiani, Richard F. (Ohio Township, Allegheny County, PA); Pollick, Richard D. (Sarver, PA); Nyilas, Charles P. (Monroeville, PA); Denmeade, Timothy J. (Lower Burrell, PA)

    1997-01-01

    A transfer pump used in a waste tank for transferring high-level radioactive liquid waste from a waste tank and having a column assembly, a canned electric motor means, and an impeller assembly with an upper impeller and a lower impeller connected to a shaft of a rotor assembly. The column assembly locates a motor housing with the electric motor means adjacent to the impeller assembly which creates an hydraulic head, and which forces the liquid waste, into the motor housing to cool the electric motor means and to cool and/or lubricate the radial and thrust bearing assemblies. Hard-on-hard bearing surfaces of the bearing assemblies and a ring assembly between the upper impeller and electric motor means grind large particles in the liquid waste flow. Slots in the static bearing member of the radial bearing assemblies further grind down the solid waste particles so that only particles smaller than the clearances in the system can pass therethrough, thereby resisting damage to and the interruption of the operation of the transfer pump. The column assembly is modular so that sections can be easily assembled, disassembled and/or removed. A second embodiment employs a stator jacket which provides an alternate means for cooling the electric motor means and lubricating and/or cooling the bearing assemblies, and a third embodiment employs a variable level suction device which allows liquid waste to be drawn into the transfer pump from varying and discrete levels in the waste tank.

  9. Intense fusion neutron sources

    SciTech Connect

    Kuteev, B. V. [Russian Research Centre Kurchatov Institute (Russian Federation); Goncharov, P. R.; Sergeev, V. Yu. [St. Petersburg State Polytechnic University (Russian Federation); Khripunov, V. I. [Russian Research Centre Kurchatov Institute (Russian Federation)

    2010-04-15

    The review describes physical principles underlying efficient production of free neutrons, up-to-date possibilities and prospects of creating fission and fusion neutron sources with intensities of 10{sup 15}-10{sup 21} neutrons/s, and schemes of production and application of neutrons in fusion-fission hybrid systems. The physical processes and parameters of high-temperature plasmas are considered at which optimal conditions for producing the largest number of fusion neutrons in systems with magnetic and inertial plasma confinement are achieved. The proposed plasma methods for neutron production are compared with other methods based on fusion reactions in nonplasma media, fission reactions, spallation, and muon catalysis. At present, intense neutron fluxes are mainly used in nanotechnology, biotechnology, material science, and military and fundamental research. In the near future (10-20 years), it will be possible to apply high-power neutron sources in fusion-fission hybrid systems for producing hydrogen, electric power, and technological heat, as well as for manufacturing synthetic nuclear fuel and closing the nuclear fuel cycle. Neutron sources with intensities approaching 10{sup 20} neutrons/s may radically change the structure of power industry and considerably influence the fundamental and applied science and innovation technologies. Along with utilizing the energy produced in fusion reactions, the achievement of such high neutron intensities may stimulate wide application of subcritical fast nuclear reactors controlled by neutron sources. Superpower neutron sources will allow one to solve many problems of neutron diagnostics, monitor nano-and biological objects, and carry out radiation testing and modification of volumetric properties of materials at the industrial level. Such sources will considerably (up to 100 times) improve the accuracy of neutron physics experiments and will provide a better understanding of the structure of matter, including that of the neutron itself.

  10. Atomic data for fusion

    SciTech Connect

    Hunter, H.T.; Kirkpatrick, M.I.; Alvarez, I.; Cisneros, C.; Phaneuf, R.A. (eds.) [eds.; Barnett, C.F.

    1990-07-01

    This report provides a handbook of recommended cross-section and rate-coefficient data for inelastic collisions between hydrogen, helium and lithium atoms, molecules and ions, and encompasses more than 400 different reactions of primary interest in fusion research. Published experimental and theoretical data have been collected and evaluated, and the recommended data are presented in tabular, graphical and parametrized form. Processes include excitation and spectral line emission, charge exchange, ionization, stripping, dissociation and particle interchange reactions. The range of collision energies is appropriate to applications in fusion-energy research.

  11. Efficient, Inexpensive Motors: A New Trend in The Motors Market 

    E-print Network

    Wroblewksi, R. G.

    2001-01-01

    The Consortiun for Energy Efficiency (CEE) has established criteria for premium-efficiency motors above the EPACT standard. CEE has set a uniform efficiency benchmark that all market players (manufacturers, utilities, and end-users) can use. Some...

  12. Data fusion of multisensor data

    Microsoft Academic Search

    Sheng Tang

    2000-01-01

    The problem of data fusion of multisensor data for multitarget tracking is considered. A hierarchical fusion system is presented for fusion of numerical data from multiple local radar stations, and a fuzzy clustering technique is introduced. Simulation results are presented for a scenario having three local radar stations and three targets with trajectories containing some type of acceleration and varying

  13. Prospects for economic fusion electricity

    Microsoft Academic Search

    I. Cook; R. L. Miller; D. J. Ward

    2002-01-01

    Extensive studies of fusion economics have been performed in the last decade within the European Union and the United States. Over the same period major advances have been made in the physics and technology of fusion. This paper summarizes the prospects for fusion making an economically attractive contribution to the future energy mix. With modest physics optimization and anticipated near-term

  14. The Fusion Machine (extended abstract)

    E-print Network

    Gardner, Philippa

    The Fusion Machine (extended abstract) Philippa Gardner Cosimo Laneve Lucian Wischik March 27, 2002. In particular, we describe a dis- tributed abstract machine called the fusion machine. In it, only channels exist at runtime. It uses a form of concurrent constraints called fusions--equations on channel names

  15. Environmental aspects of fusion reactors

    Microsoft Academic Search

    F. E. Coffman; J. M. Williams

    1975-01-01

    Potential environmental impacts of commercial fusion reactors are discussed and compared with those of fission reactors. It is shown that the environmental impact of fusion reactors will be quite small, with the main contribution coming from thermal discharges. Some attractive safety and environmental characteristics of fusion reactors are described, including an effectively infinite low-cost fuel supply, their inherent incapacity for

  16. Human-Centered Fusion Framework

    SciTech Connect

    Posse, Christian; White, Amanda M.; Beagley, Nathaniel

    2007-05-16

    In recent years the benefits of fusing signatures extracted from large amounts of distributed and/or heterogeneous data sources have been largely documented in various problems ranging from biological protein function prediction to cyberspace monitoring. In spite of significant progress in information fusion research, there is still no formal theoretical framework for defining various types of information fusion systems, defining and analyzing relations among such types, and designing information fusion systems using a formal method approach. Consequently, fusion systems are often poorly understood, are less than optimal, and/or do not suit user needs. To start addressing these issues, we outline a formal humancentered fusion framework for reasoning about fusion strategies. Our approach relies on a new taxonomy for fusion strategies, an alternative definition of information fusion in terms of parameterized paths in signature related spaces, an algorithmic formalization of fusion strategies and a library of numeric and dynamic visual tools measuring the impact as well as the impact behavior of fusion strategies. Using a real case of intelligence analysis we demonstrate that the proposed framework enables end users to rapidly 1) develop and implement alternative fusion strategies, 2) understand the impact of each strategy, 3) compare the various strategies, and 4) perform the above steps without having to know the mathematical foundations of the framework. We also demonstrate that the human impact on a fusion system is critical in the sense that small changes in strategies do not necessarily correspond to small changes in results.

  17. Third Edition, Gene Fusion System

    E-print Network

    Lai, Zhi-Chun

    Cleavage ............................. 19 Detection of GST Fusion Proteins .... 20 17. Measurement of GSTThird Edition, Revision 2 18-1123-20 GST Gene Fusion System #12;PROTEIN DATA BANK ADVISORY NOTICE. Screening pGEX Vectors with PCR ..... 10 Purification of GST Fusion Proteins.. 11 8. Preparation

  18. Tutorial 14: multisensor data fusion

    Microsoft Academic Search

    David Macii; Andrea Boni; Mariolino De Cecco; Dario Petri

    2008-01-01

    Multisensor data fusion is an emerging discipline. The rapid evolution of high-performance, inexpensive, and low-power computing components for pervasive systems, such as wireless sensor networks, will enable the development of complex sensor fusion applications. The idea underlying data fusion is to combine information collected by different sensors, to make inferences at different levels of abstraction about an entity or a

  19. Grand challenges of information fusion

    Microsoft Academic Search

    Dale A. Lambert

    2003-01-01

    The paper presents the Future Operations Centre Analysis Laboratory data34sion system, composed of both people and machines, A WDL revision of the JDL model of data fusion is proposed for this data fusion system. This leads to the identification of a number of grand challenges of information fusion. The Future Operations Centre Analysis Laboratory programme approach to these grand challenges

  20. Fusion reactor radioactive waste management

    Microsoft Academic Search

    J. D. Kaser; A. K. Postma; D. J. Bradley

    1976-01-01

    Quantities and compositions of non-tritium radioactive waste are estimated for some current conceptual fusion reactor designs, and disposal of large amounts of radioactive waste appears necessary. Although the initial radioactivity of fusion reactor and fission reactor wastes are comparable, the radionuclides in fusion reactor wastes are less hazardous and have shorter half-lives. Areas requiring further research are discussed.

  1. 41 CFR 102-34.90 - What motor vehicle identification must we display on Government motor vehicles?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...What motor vehicle identification must we display on Government motor vehicles? 102-34...What motor vehicle identification must we display on Government motor vehicles? Unless...180, Government motor vehicles must display the following identification:...

  2. 41 CFR 102-34.90 - What motor vehicle identification must we display on Government motor vehicles?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...What motor vehicle identification must we display on Government motor vehicles? 102-34...What motor vehicle identification must we display on Government motor vehicles? Unless...180, Government motor vehicles must display the following identification:...

  3. 41 CFR 102-34.90 - What motor vehicle identification must we display on Government motor vehicles?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...What motor vehicle identification must we display on Government motor vehicles? 102-34...What motor vehicle identification must we display on Government motor vehicles? Unless...180, Government motor vehicles must display the following identification:...

  4. Stable implicit motor processes despite aerobic locomotor fatigue.

    PubMed

    Masters, R S W; Poolton, J M; Maxwell, J P

    2008-03-01

    Implicit processes almost certainly preceded explicit processes in our evolutionary history, so they are likely to be more resistant to disruption according to the principles of evolutionary biology [Reber, A. S. (1992). The cognitive unconscious: An evolutionary perspective. Consciousness and Cognition, 1, 93-133.]. Previous work (e.g., [Masters, R. S. W. (1992). Knowledge, (k)nerves and know-how: The role of explicit versus implicit knowledge in the breakdown of a complex motor skill under pressure. British Journal of Psychology, 83, 343-358.]) has shown that implicitly learned motor skills remain stable under psychological pressure and concurrent cognitive demands, and recently [Poolton, J. M., Masters, R. S. W., & Maxwell, J. P. (2007). Passing thoughts on the evolutionary stability of implicit motor behaviour: Performance retention under physiological fatigue. Consciousness and Cognition, 16(2), 456-468.] showed that they also remain stable under conditions of anaerobic fatigue that would have significantly challenged the survival skills of our ancestors. Here we examine the stability of an implicitly learned motor skill under fatigue conditions that primarily tax a different physiological system (the aerobic system), but which have equally strong evolutionary connotations. Participants acquired a throwing task by means of an errorless (implicit) learning method or an errorful (explicit) method. Motor performance in the errorless condition, but not the errorful condition, remained stable following an exhaustive VO2 max. running test. Our findings replicate and extend the work of Poolton et al., providing further support for Reber's evolutionary distinction between implicit and explicit processes. PMID:17470398

  5. State observer for synchronous motors

    DOEpatents

    Lang, Jeffrey H. (Waltham, MA)

    1994-03-22

    A state observer driven by measurements of phase voltages and currents for estimating the angular orientation of a rotor of a synchronous motor such as a variable reluctance motor (VRM). Phase voltages and currents are detected and serve as inputs to a state observer. The state observer includes a mathematical model of the electromechanical operation of the synchronous motor. The characteristics of the state observer are selected so that the observer estimates converge to the actual rotor angular orientation and velocity, winding phase flux linkages or currents.

  6. Control of Fusion and Solubility in Fusion Systems David A. Craven

    E-print Network

    Craven, David A.

    Control of Fusion and Solubility in Fusion Systems David A. Craven March 2009 Abstract In this article, we consider control of fusion, quotients, and p-soluble fusion systems. For control of fusion, we for fusion systems. We move on to p-soluble fusion systems, and prove that they are constrained, allowing us

  7. 13 CFR 107.880 - Assets acquired in liquidation of Portfolio securities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...false Assets acquired in liquidation of Portfolio securities. 107.880 Section 107...880 Assets acquired in liquidation of Portfolio securities. You may acquire assets...of assets acquired in liquidation of a Portfolio security within a reasonable period...

  8. 13 CFR 107.880 - Assets acquired in liquidation of Portfolio securities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...false Assets acquired in liquidation of Portfolio securities. 107.880 Section 107...880 Assets acquired in liquidation of Portfolio securities. You may acquire assets...of assets acquired in liquidation of a Portfolio security within a reasonable period...

  9. 13 CFR 107.880 - Assets acquired in liquidation of Portfolio securities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...false Assets acquired in liquidation of Portfolio securities. 107.880 Section 107...880 Assets acquired in liquidation of Portfolio securities. You may acquire assets...of assets acquired in liquidation of a Portfolio security within a reasonable period...

  10. 13 CFR 107.880 - Assets acquired in liquidation of Portfolio securities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...false Assets acquired in liquidation of Portfolio securities. 107.880 Section 107...880 Assets acquired in liquidation of Portfolio securities. You may acquire assets...of assets acquired in liquidation of a Portfolio security within a reasonable period...

  11. 26. View, looking east, of motor house; the electric motor ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. View, looking east, of motor house; the electric motor and electric-powered winch are housed in section of building to the left. The U-bolt and concrete deadman which anchors the cable of the tramway is to the right. Photo by Jet Lowe, HAER, 1989. - Puget Sound Power & Light Company, White River Hydroelectric Project, 600 North River Avenue, Dieringer, Pierce County, WA

  12. Fusion of concurrent single trial EEG data and fMRI data using multi-set canonical correlation analysis

    Microsoft Academic Search

    Nicolle M. Correa; Tom Eichele; Tülay Adali; Yi-Ou Li; Vince D. Calhoun

    2010-01-01

    We propose a data fusion method for the fusion of simultaneously acquired functional magnetic resonance imaging (fMRI) and single trial electroencephalography (EEG) data from multiple subjects using multi-set canonical correlation analysis (M-CCA). Our proposed technique utilizes the common time series information in the multimodal datasets to find trial-to-trial covariations across modalities, and based on these covariations, the data is decomposed

  13. Sensorless vector control of induction motors at very low speed using a nonlinear inverter model and parameter identification

    Microsoft Academic Search

    Joachim Holtz; Juntao Quan

    2002-01-01

    The performance of vector-controlled induction motor drives without a speed sensor is generally poor at very low speed. The reasons are offset and drift components in the acquired feedback signals, voltage distortions caused by the nonlinear behavior of the switching converter, and the increased sensitivity against model parameter mismatch. New modeling and identification techniques are proposed to overcome these problems.

  14. An Exciting Experiment for Pre-Engineering and Introductory Physics Students: Creating a DC Motor Using the Lorentz Force

    ERIC Educational Resources Information Center

    Abdul-Razzaq, Wathiq N.; Boehm, Manfred H.; Bushey, Ryan K.

    2008-01-01

    Introductory physics laboratories have been demonstrated in some instances to be difficult or uninteresting to students at the collegiate level. We have developed a laboratory that introduces the concept of the Lorentz force and allows students to build a non-traditional DC motor out of easily acquired materials. Basic electricity and magnetism…

  15. Target-Induced Transcriptional Control of Dendritic Patterning and Connectivity in Motor Neurons by the ETS Gene Pea3

    Microsoft Academic Search

    Eline Vrieseling; Silvia Arber

    2006-01-01

    SUMMARY The apposition of axon terminals and dendrites is critical for the control of neuronal activation, but how distinct neuronal subpopulations es- tablish selective dendrite patterns and acquire specific presynaptic inputs remains unclear. Spinal motor neuron (MN) pools project to spe- cific target muscles and are activated by selec- tive synaptic inputs from group Ia propriocep- tive afferents (IaPAs). Here,

  16. Analysis of HB Type Vernier Motor

    Microsoft Academic Search

    Hiroshi Suda; Yoshitaro Matsushima; Li Xu; Yoshihisa Anazawa

    2005-01-01

    Direct drive motors are used as actuators in numerous applications in which they must rotate at low speeds with high torque and low torque ripple. Recently, various types of vernier motor have been developed. The HB type vernier motor is one of them. The structure of rotor is the same as HB type stepping motor. Our model of HB type

  17. Proprioception and Motor Control in Parkinson's Disease

    Microsoft Academic Search

    Jürgen Konczak; Daniel M. Corcos; Fay Horak; Howard Poizner; Mark Shapiro; Paul Tuite; Jens Volkmann; Matthias Maschke

    2009-01-01

    Parkinson's disease (PD) is a neurodegenerative disorder that leads to a progressive decline in motor function. Growing evidence indicates that PD patients also experience an array of sensory problems that negatively impact motor function. This is especially true for proprioceptive deficits, which profoundly degrade motor performance. This review specifically address the relation between proprioception and motor impairments in PD. It

  18. High-speed stepper motor for mechanism

    Microsoft Academic Search

    Jean-François Oudet; François Pagnon

    2003-01-01

    The hybrid stepper motor are particularly well suited for motorization requirement in space mechanism. These applications are characterised by accurate positioning and slow speed or quasi-steady state, and are usually based on open loop control. Hybrid Stepper Motor driving is usually easy. A high speed stepper motor size 35 was developed to satisfy this requirement. The first step consisted in

  19. High temperature superconductivity applied to electric motors

    Microsoft Academic Search

    J. D. Edick; R. F. Schiferl; H. E. Jordan

    1992-01-01

    The application of high temperature superconductors to electric motors is discussed. Both the advantages and limitations of using superconductors in motors are reviewed. A synchronous motor with a high-temperature superconductor field winding for pump and fan drive applications is described and some of its unique features are identified. A 10000-hp superconducting motor design and its advantages in terms of improved

  20. Rotary protein motors George Oster1

    E-print Network

    Oster, George

    unambiguously iden- tified as rotary engines: the bacterial flagellar motor and the two motors that constituteRotary protein motors George Oster1 and Hongyun Wang2 1 Depts Molecular and Cellular Biology review the current understanding of how these protein motors convert their energy supply into a rotary

  1. Rotary protein motors George Oster1

    E-print Network

    Wang, Hongyun

    unambiguously iden- tified as rotary engines: the bacterial flagellar motor and the two motors that constitute#12;Rotary protein motors George Oster1 and Hongyun Wang2 1 Depts Molecular and Cellular Biology review the current understanding of how these protein motors convert their energy supply into a rotary

  2. Modeling of permanent magnet motor drives

    Microsoft Academic Search

    PRAGASAN PILLAY; R. Krishnan

    1988-01-01

    Research has indicated that the permanent magnet motor drives, which include the permanent magnet synchronous motor (PMSM) and the brushless DC motor (BDCM) could become serious competitors to the induction motor for servo applications. The PMSM has a sinusoidal back EMF and requires sinusoidal stator currents to produce constant torque while the BDCM has a trapezoidal back EMF and requires

  3. NDT Data Fusion

    Microsoft Academic Search

    Alistair McNab

    1997-01-01

    Data fusion is a topic which is currently causing much interest. In NDT, the combining of data from a number of independent sources related to the same test component can provide a more complete and accurate assessment of any flaws present. Ultrasonic testing, radiographic and eddy current inspection, as well as other methods, can provide the required diversity of information.

  4. Information Fusion user name

    E-print Network

    Hefei Institute of Intelligent Machines

    nmlkj by editor Browse for journals Search our full text articles gfedcb Search only in Computer Science policy | contact us ?copyright Elsevier Page 1 of 1Elsevier Author Gateway 5/18/2003http://authors.elsevier.com/Journal Powered by Search An International Journal on Multi-Sensor, Multi-Source Information Fusion Guide

  5. Materials for fusion reactors

    Microsoft Academic Search

    1978-01-01

    Material problems for fusion reactor consist of finding materials to be used for the first wall, limiters, electrical insulation, neutron moderators, shielding, and component for superconducting magnets. Materials being considered for the first wall include austenitic stainless steel, nickel, titanium, refractory metals and aluminium alloys. TiC, graphite, copper, and refractory metals are being evaluated for limiters which are used to

  6. Advanced spheromak fusion reactor

    Microsoft Academic Search

    T. K. Fowler; E. B. Hooper

    1996-01-01

    The spheromak has no toroidal magnetic field coils or other structure along its geometric axis, and is thus more attractive than the leading magnetic fusion reactor concept, the tokamak. As a consequence of this and other attributes, the spheromak reactor may be compact and produce a power density sufficiently high to warrant consideration of a liquid `blanket` that breeds tritium,

  7. Spherical torus fusion reactor

    Microsoft Academic Search

    Peng; Yueng-Kay M

    1989-01-01

    A fusion reactor is provided having a near spherical-shaped plasma with a modest central opening through which straight segments of toroidal field coils extend that carry electrical current for generating a toroidal magnet plasma confinement fields. By retaining only the indispensable components inboard of the plasma torus, principally the cooled toroidal field conductors and in some cases a vacuum containment

  8. DT Beam Fusion Reactor

    Microsoft Academic Search

    F. J. Wessel; N. Rostoker

    1998-01-01

    The Beam Fusion Reactor (BFR) is based on a field-reversed configuration and confined ion energies in the range of hundreds of keV. Repetitively pulsed, intense ion beams sustain the ion distributions and provide current drive. In the BFR the ion orbit size is comparable to the dimensions of the confined plasma and the expectation is for classical transport of the

  9. Multisensor data fusion

    Microsoft Academic Search

    P. K. Varshney

    1997-01-01

    Multisensor data fusion refers to the acquisition, processing and synergistic combination of information gathered by various knowledge sources and sensors to provide a better understanding of a phenomenon. It is a fascinating and rapidly evolving field that has generated a lot of excitement in the research and development community. These concepts are being applied to a wide variety of fields

  10. Compact fusion reactors

    SciTech Connect

    Krakowski, R.A.; Hagenson, R.L.

    1983-01-01

    Compact, high-power-density approaches to fusion power are proposed to improve economic viability through the use of less-advanced technology in systems of considerably reduced scale. The rationale for and the means by which these systems can be achieved are discussed, as are unique technological problems.

  11. Soldier systems sensor fusion

    Microsoft Academic Search

    Kathryne M. Brubaker

    1998-01-01

    This paper addresses sensor fusion and its applications in emerging Soldier Systems integration and the unique challenges associated with the human platform. Technology that,provides the highest operational payoff in a lightweight warrior system must not only have enhanced capabilities, but have low power components resulting in order of magnitude reductions coupled with significant cost reductions. These reductions in power and

  12. Context based multimodal fusion

    Microsoft Academic Search

    Norbert Pfleger

    2004-01-01

    We present a generic approach to multimodal fusion which we call context based multimodal integration. Key to this approach is that every multimodal input event is interpreted and enriched with respect to its local turn context. This local turn context comprises all previously recognized input events and the dialogue state that both belong to the same user turn. We show

  13. Fusion Chamber Technology Publications

    E-print Network

    California at Los Angeles, University of

    Coatings on the Flow Partitioning Between Parallel Channels in Self-Cooled Liquid Metal Blankets," Fusion, Z. "Thermal and Mechanical Properties of Ceramic Blanket Particle Bed Materials: Numerical. Abelson, R.D., Abdou, M.A. "Experimental Measurement of the Interface Heat Conductance Between

  14. Multisensor data fusion architecture

    Microsoft Academic Search

    A. H. G. Al-Dhaher; D. Mackesy

    2004-01-01

    In this work we present multi-sensor data fusion architecture. The objective of the architecture is to obtain fused measured data that represent the measured parameter as accurate as possible. The architecture is based on the use of adaptive Kalman filter formed by using Kalman filter and fuzzy logic techniques. Measurements generated from each sensor are fed into an adaptive Kalman

  15. Recover Power with Hydraulic Motors

    E-print Network

    Brennan, J. R.

    1982-01-01

    displacement device, the HPRM torque and speed are almost completely independent - unlike hydraulic power recovery turbines (centrifugal motors). Three screw HPRM's have low moments of inertia, operate at low vibration and noise levels and extract power...

  16. Drill-motor holding fixture

    NASA Technical Reports Server (NTRS)

    Chartier, E. N.; Culp, L. N.

    1980-01-01

    Guide improves accuracy and reduces likelihood of bit breakage in drilling large work pieces. Drill motor is mounted on pipe that slides on furniture clamp. Drill is driven into work piece by turning furniture-clamp handle.

  17. Fatigue in motor neuron diseases.

    PubMed

    Abraham, Alon; Drory, Vivian E

    2012-12-01

    Motor neuron diseases as amyotrophic lateral sclerosis and post-polio syndrome are characterized by prominent muscular weakness and severe motor disability. The prevalence of fatigue in motor neuron diseases is remarkably high, and may contribute significantly to patients' disability and a poor quality of life. Despite its high prevalence, fatigue is an understudied clinical problem in motor neuron diseases and is often overlooked. The present review will attempt to explain the pathogenic mechanisms of muscle fatigue in amyotrophic lateral sclerosis and post-polio syndrome, to cover the various methods of quantification of fatigue that measure both subjective and physiological components, and to summarize the evidence regarding therapeutic interventions that can be used in order to minimize this symptom. PMID:23182639

  18. Enhanced image capture through fusion

    NASA Technical Reports Server (NTRS)

    Burt, Peter J.; Hanna, Keith; Kolczynski, Raymond J.

    1993-01-01

    Image fusion may be used to combine images from different sensors, such as IR and visible cameras, to obtain a single composite with extended information content. Fusion may also be used to combine multiple images from a given sensor to form a composite image in which information of interest is enhanced. We present a general method for performing image fusion and show that this method is effective for diverse fusion applications. We suggest that fusion may provide a powerful tool for enhanced image capture with broad utility in image processing and computer vision.

  19. Fusion Probability in Dinuclear System

    E-print Network

    Juhee Hong

    2015-03-26

    Fusion can be described by the time evolution of a dinuclear system with two degrees of freedom, the relative motion and transfer of nucleons. In the presence of the coupling between two collective modes, we solve the Fokker-Planck equation in a locally harmonic approximation. The potential of a dinuclear system has the quasifission barrier and the inner fusion barrier, and the escape rates can be calculated by the Kramers' model. To estimate the fusion probability, we calculate the quasifission rate and the fusion rate. We investigate the coupling effects on the fusion probability and the cross section of evaporation residue.

  20. Fusion Ignition Research Experiment (FIRE)

    NSDL National Science Digital Library

    A division of the Princeton Plasma Research Laboratory (described in the July 1, 1994 Scout Report for Science & Engineering), the Fusion Ignition Research Experiment (FIRE) aims "to attain, explore, understand and optimize alpha-dominated plasmas to provide knowledge for the design of attractive Magnetic Fusion systems." Up-to-date, downloadable reports (.pdf and MS Word formats) contain background information and reviews of US fusion policy, Snowmass Fusion Summer Study working group summaries, FIRE reports on physics and engineering design considerations, and an engineering appendix. Clearly displayed, this site harbors a wealth of dense information for researchers interested in the design of magnetic fusion systems.

  1. Accelerators for heavy ion fusion

    SciTech Connect

    Bangerter, R.O.

    1985-10-01

    Large fusion devices will almost certainly produce net energy. However, a successful commercial fusion energy system must also satisfy important engineering and economic constraints. Inertial confinement fusion power plants driven by multi-stage, heavy-ion accelerators appear capable of meeting these constraints. The reasons behind this promising outlook for heavy-ion fusion are given in this report. This report is based on the transcript of a talk presented at the Symposium on Lasers and Particle Beams for Fusion and Strategic Defense at the University of Rochester on April 17-19, 1985.

  2. Rethinking responsibility in offenders with acquired paedophilia: punishment or treatment?

    PubMed

    Gilbert, Frédéric; Focquaert, Farah

    2015-01-01

    This article reviews the current neurobiological literature on the aetiology of developmental and acquired paedophilia and examines what the consequences could be in terms of responsibility and treatment for the latter. Addressing the question of responsibility and punishment of offenders with acquired paedophilia from a neurobiological perspective is controversial. Consequently it is essential to avoid hasty conclusions based strictly on neurobiological abnormality justifications. This study establishes a distinction between developmental and acquired paedophilia. The article investigates whether offenders who fulfil the diagnosis of acquired paedophilia should be held fully responsible, particularly in cases where the offender's conduct appears to result from volitionally controlled behaviour that is seemingly incompatible with a neurological cause. Moreover, the article explores how responsibility can be compromised when offenders with acquired paedophilia have (partially) preserved moral knowledge despite their sexual disorder. The article then examines the option of offering mandatory treatment as an alternative to imprisonment for offenders with acquired paedophilia. Furthermore, the article addresses the ethical issues related to offering any form of quasi-coercive treatment as a condition of release. This study concludes that decisions to fully or partially excuse an individual who fulfil the diagnosis of acquired paedophilia should take all relevant information into account, both neurobiological and other environmental evidence, and should proceed on a careful case by case analysis before sentencing or offering treatment. PMID:25725545

  3. The evolution of resistance through costly acquired immunity.

    PubMed Central

    Boots, Michael; Bowers, Roger G.

    2004-01-01

    We examine the evolutionary dynamics of resistance to parasites through acquired immunity. Resistance can be achieved through the innate mechanisms of avoidance of infection and reduced pathogenicity once infected, through recovery from infection and through remaining immune to infection: acquired immunity. We assume that each of these mechanisms is costly to the host and find that the evolutionary dynamics of innate immunity in hosts that also have acquired immunity are quantitatively the same as in hosts that possess only innate immunity. However, compared with resistance through avoidance or recovery, there is less likely to be polymorphism in the length of acquired immunity within populations. Long-lived organisms that can recover at intermediate rates faced with fast-transmitting pathogens that cause intermediate pathogenicity (mortality of infected individuals) are most likely to evolve long-lived acquired immunity. Our work emphasizes that because whether or not acquired immunity is beneficial depends on the characteristics of the disease, organisms may be selected to only develop acquired immunity to some of the diseases that they encounter. PMID:15209105

  4. A soft and dexterous motor

    NASA Astrophysics Data System (ADS)

    Anderson, Iain A.; Tse, Tony Chun Hin; Inamura, Tokushu; O'Brien, Benjamin M.; McKay, Thomas; Gisby, Todd

    2011-03-01

    We present a soft, bearing-free artificial muscle motor that cannot only turn a shaft but also grip and reposition it through a flexible gear. The bearing-free operation provides a foundation for low complexity soft machines, with multiple degree-of-freedom actuation, that can act simultaneously as motors and manipulators. The mechanism also enables an artificial muscle controlled gear change. Future work will include self-sensing feedback for precision, multidegree-of-freedom operation.

  5. Federal Motor Carrier Safety Administration

    NSDL National Science Digital Library

    This is the home website for the Federal Motor Carrier Safety Administration (FMCSA). This agency was established as a separate administration within the U.S. Department of Transportation pursuant to the Motor Carrier Safety Improvement Act of 1999. Their primary mission is to reduce crashes, injuries, and fatalities involving large trucks and buses. There is also information on their website involving anti-terrorism tips for transporters.

  6. Motor activity improves temporal expectancy.

    PubMed

    Fautrelle, Lilian; Mareschal, Denis; French, Robert; Addyman, Caspar; Thomas, Elizabeth

    2015-01-01

    Certain brain areas involved in interval timing are also important in motor activity. This raises the possibility that motor activity might influence interval timing. To test this hypothesis, we assessed interval timing in healthy adults following different types of training. The pre- and post-training tasks consisted of a button press in response to the presentation of a rhythmic visual stimulus. Alterations in temporal expectancy were evaluated by measuring response times. Training consisted of responding to the visual presentation of regularly appearing stimuli by either: (1) pointing with a whole-body movement, (2) pointing only with the arm, (3) imagining pointing with a whole-body movement, (4) simply watching the stimulus presentation, (5) pointing with a whole-body movement in response to a target that appeared at irregular intervals (6) reading a newspaper. Participants performing a motor activity in response to the regular target showed significant improvements in judgment times compared to individuals with no associated motor activity. Individuals who only imagined pointing with a whole-body movement also showed significant improvements. No improvements were observed in the group that trained with a motor response to an irregular stimulus, hence eliminating the explanation that the improved temporal expectations of the other motor training groups was purely due to an improved motor capacity to press the response button. All groups performed a secondary task equally well, hence indicating that our results could not simply be attributed to differences in attention between the groups. Our results show that motor activity, even when it does not play a causal or corrective role, can lead to improved interval timing judgments. PMID:25806813

  7. Direct drive field actuator motors

    DOEpatents

    Grahn, Allen R. (Salt Lake City, UT)

    1998-01-01

    A positive-drive field actuator motor including a stator carrying at least one field actuator which changes in dimension responsive to application of an energy field, and at least one drive shoe movable by the dimensional changes of the field actuator to contact and move a rotor element with respect to the stator. Various embodiments of the motor are disclosed, and the rotor element may be moved linearly or arcuately.

  8. Direct drive field actuator motors

    DOEpatents

    Grahn, A.R.

    1998-03-10

    A positive-drive field actuator motor is described which includes a stator carrying at least one field actuator which changes in dimension responsive to application of an energy field, and at least one drive shoe movable by the dimensional changes of the field actuator to contact and move a rotor element with respect to the stator. Various embodiments of the motor are disclosed, and the rotor element may be moved linearly or arcuately. 62 figs.

  9. An Information Fusion Framework for Threat Assessment

    SciTech Connect

    Beaver, Justin M [ORNL; Kerekes, Ryan A [ORNL; Treadwell, Jim N [ORNL

    2009-01-01

    Modern enterprises are becoming increasingly sensitive to the potential destructive power of small groups or individuals with malicious intent. In response, significant investments are being made in developing a means to assess the likelihood of certain threats to their enterprises. Threat assessment needs are typically focused in very specific application areas where current processes rely heavily on human analysis to both combine any available data and draw conclusions about the probability of a threat. A generic approach to threat assessment is proposed, including a threat taxonomy and decision-level information fusion framework, that provides a computational means for merging multi-modal data for the purpose of assessing the presence of a threat. The framework is designed for flexibility, and intentionally accounts for the accuracy of each data source, given the environmental conditions, in order to manage the uncertainty associated with any acquired data. The taxonomy and information fusion framework is described, and discussed in the context of real-world applications such as shipping container security and cyber security.

  10. Synthetic Motors and Nanomachines.

    NASA Astrophysics Data System (ADS)

    Flood, Amar

    2006-03-01

    A bistable and palindromically-constituted [3]rotaxane incorporating two mechanically-mobile rings interlocked around a linear dumbbell component, has been designed to operate like the sarcomeres of skeletal muscle. Contraction and extension occurs when the inter-ring distance of the two rings switch, ideally, between 4.2 and 1.4 nm upon redox stimulation either chemically or electrochemically in the solution phase. When the mobile rings of these artificial molecular muscles are bound onto the tops of gold-coated, micron-scale cantilever beams, their controllable nanometer motions have a chance to be amplified along the long axis of each cantilever. It turns out that ˜6 billion of the self-assembled [3]rotaxanes can bend the cantilevers in a bistable manner concomitant with the cycled addition of redox agents. The extent of bending is commensurate with 10's of pN of force per [3]rotaxane. Recent studies on a set of ``single-shot'' control [2]rotaxanes have provided additional evidence for the origins of the force generation as it arises from a molecule-based electrostatic repulsion energy of about 10 kcal/mol at 300 K. These findings will be presented in terms of the underlying thermodynamics and kinetics that have been utilized extensively to direct the design and synthesis of artificial molecular machines and which may also serve as a guide for the rational design of unidirectional molecular motors.

  11. The path to fusion power.

    PubMed

    Llewellyn Smith, Chris; Ward, David

    2007-04-15

    Fusion is potentially an environmentally responsible and intrinsically safe source of essentially limitless power. It should be possible to build viable fusion power stations, and it looks as if the cost of fusion power will be reasonable. But time is needed to further develop the technology and to test in power station conditions the materials that would be used in their construction. Assuming no major adverse surprises, an orderly fusion development programme could lead to a prototype fusion power station putting electricity into the grid within 30 years, with commercial fusion power following some 10 or more years later. In the second half of the century, fusion could therefore be an important part of the portfolio of measures that are needed to cope with rising demand for energy in an environmentally responsible manner. In this paper, we describe the basics of fusion, its potential attractions, the status of fusion R&D, the remaining challenges and how they will be tackled at the International Tokamak Experimental Reactor and the proposed International Fusion Materials Irradiation Facility, and the timetable for the subsequent commercialization of fusion power. PMID:17272246

  12. Research on fusion neutron sources

    SciTech Connect

    Gryaznevich, M. P. [Tokamak Solutions UK, Culham Science Centre, Abingdon, OXON, OX133DB (United Kingdom)

    2012-06-19

    The use of fusion devices as powerful neutron sources has been discussed for decades. Whereas the successful route to a commercial fusion power reactor demands steady state stable operation combined with the high efficiency required to make electricity production economic, the alternative approach to advancing the use of fusion is free of many of complications connected with the requirements for economic power generation and uses the already achieved knowledge of Fusion physics and developed Fusion technologies. 'Fusion for Neutrons' (F4N), has now been re-visited, inspired by recent progress achieved on comparably compact fusion devices, based on the Spherical Tokamak (ST) concept. Freed from the requirement to produce much more electricity than used to drive it, a fusion neutron source could be efficiently used for many commercial applications, and also to support the goal of producing energy by nuclear power. The possibility to use a small or medium size ST as a powerful or intense steady-state fusion neutron source (FNS) is discussed in this paper in comparison with the use of traditional high aspect ratio tokamaks. An overview of various conceptual designs of compact fusion neutron sources based on the ST concept is given and they are compared with a recently proposed Super Compact Fusion Neutron Source (SCFNS), with major radius as low as 0.5 metres but still able to produce several MW of neutrons in a steady-state regime.

  13. Design of a synchronous reluctance motor drive

    Microsoft Academic Search

    T. J. E. Miller; C. Cossar; A. J. Hutton

    1989-01-01

    A segmental-rotor synchronous reluctance motor is used in a variable-speed drive with current-regulated PWM control. The low-speed torque capability is compared with those of an induction motor, a switched reluctance motor, and a brushless DC permanent magnet (PM) motor of identical size and copper weight. The results suggest that many of the desirable properties of the switched reluctance motor can

  14. The Bliss of Motor Abundance

    PubMed Central

    Latash, Mark L.

    2012-01-01

    Motor control is an area of natural science exploring how the nervous system interacts with other body parts and the environment to produce purposeful, coordinated actions. A central problem of motor control – the problem of motor redundancy – was formulated by Nikolai Bernstein as the problem of elimination of redundant degrees-of-freedom. Traditionally, this problem has been addressed using optimization methods based on a variety of cost functions. This review draws attention to a body of recent findings suggesting that the problem has been formulated incorrectly. An alternative view has been suggested as the principle of abundance, which considers the apparently redundant degrees-of-freedom as useful and even vital for many aspects of motor behavior. Over the past ten years, dozens of publications have provided support for this view based on the ideas of synergic control, computational apparatus of the uncontrolled manifold hypothesis, and the equilibrium-point (referent configuration) hypothesis. In particular, large amounts of “good variance” – variance in the space of elements that has no effect on the overall performance – have been documented across a variety of natural actions. “Good variance” helps an abundant system to deal with secondary tasks and unexpected perturbations; its amount shows adaptive modulation across a variety of conditions. These data support the view that there is no problem of motor redundancy; there is bliss of motor abundance. PMID:22246105

  15. Precision stop control for motors

    NASA Technical Reports Server (NTRS)

    Howard, David E. (Inventor); Montenegro, Justino (Inventor)

    2000-01-01

    An improved stop control system and method are provided for a motor having a drive mechanism in which the motor is coupled to a motor controller that controls the speed and position of the drive mechanism using a first signal indicative of a commanded position of the drive mechanism, a second signal indicative of the actual speed of the drive mechanism and a third signal indicative of the actual position of the drive mechanism. The improved system/method uses a first circuit that receives the first and third signal and generates an error signal indicative of a difference therebetween. A second circuit receives the error signal and compares same with a threshold position error. The result of this comparison is used to selectively supply the second signal (i.e., speed) to the motor controller at least whenever the error signal is less than the threshold position error so that the motor controller can use the second signal in conjunction with the third signal to stop the motor.

  16. The Need for Fusion Propulsion

    NASA Technical Reports Server (NTRS)

    Cassibry, Jason

    2005-01-01

    Fusion propulsion is inevitable if the human race remains dedicated to exploration of the solar system. There are fundamental reasons why fusion surpasses more traditional approaches to routine crewed missions to Mars, crewed missions to the outer planets, and deep space high speed robotic missions, assuming that reduced trip times, increased payloads, and higher available power are desired. A recent series of informal discussions were held among members from government, academia, and industry concerning fusion propulsion. We compiled a sufficient set of arguments for utilizing fusion in space. If the U.S. is to lead the effort and produce a working system in a reasonable amount of time, NASA must take the initiative, relying on, but not waiting for, DOE guidance. In this talk those arguments for fusion propulsion are presented, along with fusion enabled mission examples, fusion technology trade space, and a proposed outline for future efforts.

  17. Dramatic regression of presumed acquired retinal astrocytoma with photodynamic therapy.

    PubMed

    Tuncer, Samuray; Cebeci, Zafer

    2014-01-01

    Photodynamic therapy (PDT) has been used for treatment of various intraocular tumors including choroidal hemangioma, vasoproliferative tumor, amelanotic choroidal melanoma and choroidal neovascular membrane due to choroidal osteoma. This case report documents the effect of PDT for a presumed acquired retinal astrocytoma. A 42-year-old female with a juxtapapillary acquired astrocytoma was treated with a single session of PDT using standard parameters. The tumor showed dramatic regression over 6 months into a fibrotic scar. It remained regressed and stable with 20/20 vision after 51 months of follow-up. We believe that PDT can be used as a primary treatment for acquired retinal astrocytoma. PMID:25100919

  18. Dramatic Regression of Presumed Acquired Retinal Astrocytoma with Photodynamic Therapy

    PubMed Central

    Tuncer, Samuray; Cebeci, Zafer

    2014-01-01

    Photodynamic therapy (PDT) has been used for treatment of various intraocular tumors including choroidal hemangioma, vasoproliferative tumor, amelanotic choroidal melanoma and choroidal neovascular membrane due to choroidal osteoma. This case report documents the effect of PDT for a presumed acquired retinal astrocytoma. A 42-year-old female with a juxtapapillary acquired astrocytoma was treated with a single session of PDT using standard parameters. The tumor showed dramatic regression over 6 months into a fibrotic scar. It remained regressed and stable with 20/20 vision after 51 months of follow-up. We believe that PDT can be used as a primary treatment for acquired retinal astrocytoma. PMID:25100919

  19. Acquired factor VII deficiency associated with acute myeloid leukemia.

    PubMed

    Anoun, Soumaya; Lamchahab, Mouna; Oukkache, Bouchra; Qachouh, Maryam; Benchekroun, Said; Quessar, Asmaa

    2015-04-01

    Isolated acquired factor VII deficiency is a rare coagulopathy. It has been reported in 31 patients with malignancy, sepsis, postoperatively, aplastic anemia, and during bone marrow transplantation. We discuss, through a new case of acquired factor VII deficiency, the characteristics of this disease when it is associated with acute myeloid leukemia. Acquired factor VII deficiency in hematological diseases can be caused by intensive chemotherapy, infections, or hepatic dysfunction. The best treatment in developing countries remains corticosteroids associated with plasma exchange, frozen plasma, and antibiotics. PMID:24991944

  20. A case of acquired idiopathic pterygium inversum unguis.

    PubMed

    Baek, Ji Hye; Kim, Hei Sung; Park, Young Min; Kim, Hyung Ok; Cho, Baik Kee; Lee, Jun Young

    2014-06-01

    Pterygium inversum unguis (PIU) is a rare nail abnormality in which the distal nail bed adheres to the ventral surface of the nail plate, with obliteration of the distal groove. Because of the rarity of this condition, its exact origin is unknown. This disorder can be either congenital or acquired, with or without a family history. The acquired forms may be idiopathic or secondary to systemic connective tissue diseases or other causes such as stroke, neurofibromatosis, leprosy, or the use of nail fortifiers. We present an unusual case of acquired idiopathic PIU of the 10 fingernails in a 22-year-old man. PMID:24966638

  1. MAGNETIC INDUCTION MACHINES EMBEDDED IN FUSION-BONDED SILICON David P. Arnold*, Florent Cros, Iulica Zana, and Mark G. Allen

    E-print Network

    MAGNETIC INDUCTION MACHINES EMBEDDED IN FUSION-BONDED SILICON David P. Arnold*, Florent Cros the design, fabrication, and characterization of laminated, magnetic induction machines intended for high-bonded silicon to form the machine structure. The induction machines were characterized in motoring mode using

  2. Uncorrelated multiway discriminant analysis for motor imagery EEG classification.

    PubMed

    Liu, Ye; Zhao, Qibin; Zhang, Liqing

    2015-06-01

    Motor imagery-based brain-computer interfaces (BCIs) training has been proved to be an effective communication system between human brain and external devices. A practical problem in BCI-based systems is how to correctly and efficiently identify and extract subject-specific features from the blurred scalp electroencephalography (EEG) and translate those features into device commands in order to control external devices. In real BCI-based applications, we usually define frequency bands and channels configuration that related to brain activities beforehand. However, a steady configuration usually loses effects due to individual variability among different subjects in practical applications. In this study, a robust tensor-based method is proposed for a multiway discriminative subspace extraction from tensor-represented EEG data, which performs well in motor imagery EEG classification without the prior neurophysiologic knowledge like channels configuration and active frequency bands. Motor imagery EEG patterns in spatial-spectral-temporal domain are detected directly from the multidimensional EEG, which may provide insights to the underlying cortical activity patterns. Extensive experiment comparisons have been performed on a benchmark dataset from the famous BCI competition III as well as self-acquired data from healthy subjects and stroke patients. The experimental results demonstrate the superior performance of the proposed method over the contemporary methods. PMID:25986750

  3. Theoretical solid-propellant rocket motor internal ballistic performance

    NASA Astrophysics Data System (ADS)

    McAmis, R. W.; Le, T. V.

    1992-07-01

    Theoretical methods for calculating solid-propellant rocket motor (SRM) internal ballistic performance were investigated and demonstrated through application to a full-scale Minuteman III Stage III motor (MM III SIII). The propellant grain burning surface location as a function of time and internal ballistic performance were calculated and compared to experimental data previously acquired at the Arnold Engineering Development Center (AEDC). Propellant burning surface location as a function of time was calculated using the theoretical code RECESS and compared within 1 sec of previously obtained real-time radiographic data of the propellant burning surface location. Ballistic performance, calculated using the theoretical code VOLFIL, compared within 8 percent of experimental data obtained from the MM III SIII motor test. Both codes provide a firm basis for evaluating nominal SRM performance. Ballistic calculations can be improved simply by coupling ballistics to grain burnback allowing burn rate to vary with pressure. Future work will incorporate coupled solutions among the case and propellant structural response, grain burnback, and ballistics.

  4. Ready, Set, Fuse! The Coronavirus Spike Protein and Acquisition of Fusion Competence

    PubMed Central

    Heald-Sargent, Taylor; Gallagher, Tom

    2012-01-01

    Coronavirus-cell entry programs involve virus-cell membrane fusions mediated by viral spike (S) proteins. Coronavirus S proteins acquire membrane fusion competence by receptor interactions, proteolysis, and acidification in endosomes. This review describes our current understanding of the S proteins, their interactions with and their responses to these entry triggers. We focus on receptors and proteases in prompting entry and highlight the type II transmembrane serine proteases (TTSPs) known to activate several virus fusion proteins. These and other proteases are essential cofactors permitting coronavirus infection, conceivably being in proximity to cell-surface receptors and thus poised to split entering spike proteins into the fragments that refold to mediate membrane fusion. The review concludes by noting how understanding of coronavirus entry informs antiviral therapies. PMID:22590686

  5. 77 FR 26607 - Energy Conservation Program: Test Procedures for Electric Motors and Small Electric Motors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ...Part 431 Energy Conservation Program: Test Procedures for Electric Motors and Small...1904-AC05 Energy Conservation Program: Test Procedures for Electric Motors and Small...notice of proposed rulemaking to amend the test procedures for electric motors and...

  6. Gene Expression Changes in the Motor Cortex Mediating Motor Skill Learning

    E-print Network

    Cheung, Vincent Chi-Kwan

    The primary motor cortex (M1) supports motor skill learning, yet little is known about the genes that contribute to motor cortical plasticity. Such knowledge could identify candidate molecules whose targeting might enable ...

  7. A Study on a Brain-Computer Interface for Motor Assist by Prefrontal Cortex

    NASA Astrophysics Data System (ADS)

    Misawa, Tadanobu; Takano, Shinya; Shimokawa, Tetsuya; Hirobayashi, Shigeki

    In recent times, considerable research has been conducted on the development of brain-computer interfaces (BCIs). Although there have been several reports on BCIs that assist motor functions by measurement of brain activity in the motor cortex, only a few studies have reported on BCI that assist motor functions by measurement of activity in areas other than the motor cortex. In this study, we experimentally develop a BCI that assists motor functions on the basis of brain activity in the prefrontal cortex. In this BCI system, subjects are shown the labyrinth problem. Concretely, brain activity is measured using fNIRS and the data are acquired in real time. The signal processing module implements low pass filtering of these signals. Further, the pattern classification module used in this system currently is a support vector machine. 22 subjects, both male and female, volunteered to participate in this experiment. 8 of these 22 subjects were able to solve the labyrinth problem. In this experiment, we could not obtain a high distinction. However, these results show that it is possible to develop BCI systems that assist motor functions using information from the prefrontal cortex.

  8. Acquisition, representation, and transfer of models of visuo-motor error

    PubMed Central

    Zhang, Hang; Kulsa, Mila Kirstie C.; Maloney, Laurence T.

    2015-01-01

    We examined how human subjects acquire and represent models of visuo-motor error and how they transfer information about visuo-motor error from one task to a closely related one. The experiment consisted of three phases. In the training phase, subjects threw beanbags underhand towards targets displayed on a wall-mounted touch screen. The distribution of their endpoints was a vertically elongated bivariate Gaussian. In the subsequent choice phase, subjects repeatedly chose which of two targets varying in shape and size they would prefer to attempt to hit. Their choices allowed us to investigate their internal models of visuo-motor error distribution, including the coordinate system in which they represented visuo-motor error. In the transfer phase, subjects repeated the choice phase from a different vantage point, the same distance from the screen but with the throwing direction shifted 45°. From the new vantage point, visuo-motor error was effectively expanded horizontally by . We found that subjects incorrectly assumed an isotropic distribution in the choice phase but that the anisotropy they assumed in the transfer phase agreed with an objectively correct transfer. We also found that the coordinate system used in coding two-dimensional visuo-motor error in the choice phase was effectively one-dimensional. PMID:26057549

  9. Combinations of stroke neurorehabilitation to facilitate motor recovery: perspectives on Hebbian plasticity and homeostatic metaplasticity

    PubMed Central

    Takeuchi, Naoyuki; Izumi, Shin-Ichi

    2015-01-01

    Motor recovery after stroke involves developing new neural connections, acquiring new functions, and compensating for impairments. These processes are related to neural plasticity. Various novel stroke rehabilitation techniques based on basic science and clinical studies of neural plasticity have been developed to aid motor recovery. Current research aims to determine whether using combinations of these techniques can synergistically improve motor recovery. When different stroke neurorehabilitation therapies are combined, the timing of each therapeutic program must be considered to enable optimal neural plasticity. Synchronizing stroke rehabilitation with voluntary neural and/or muscle activity can lead to motor recovery by targeting Hebbian plasticity. This reinforces the neural connections between paretic muscles and the residual motor area. Homeostatic metaplasticity, which stabilizes the activity of neurons and neural circuits, can either augment or reduce the synergic effect depending on the timing of combination therapy and types of neurorehabilitation that are used. Moreover, the possibility that the threshold and degree of induced plasticity can be altered after stroke should be noted. This review focuses on the mechanisms underlying combinations of neurorehabilitation approaches and their future clinical applications. We suggest therapeutic approaches for cortical reorganization and maximal functional gain in patients with stroke, based on the processes of Hebbian plasticity and homeostatic metaplasticity. Few of the possible combinations of stroke neurorehabilitation have been tested experimentally; therefore, further studies are required to determine the appropriate combination for motor recovery. PMID:26157374

  10. Acquired Auditory Verbal Agnosia and Seizures in Childhood

    ERIC Educational Resources Information Center

    Cooper, Judith A.; Ferry, Peggy C.

    1978-01-01

    The paper presents a review of cases of children with acquired aphasia with convulsive disorder and discusses clinical features of three additional children in whom the specific syndrome of auditory verbal agnosia was identified. (Author/CL)

  11. Acquired dyslexia in a Turkish-English speaker.

    PubMed

    Raman, Ilhan; Weekes, Brendan S

    2005-06-01

    The Turkish script is characterised by completely transparent bidirectional mappings between orthography and phonology. To date, there has been no reported evidence of acquired dyslexia in Turkish speakers leading to the naïve view that reading and writing problems in Turkish are probably rare. We examined the extent to which phonological impairment and orthographic transparency influence reading disorders in a native Turkish speaker. BRB is a bilingual Turkish-English speaker with deep dysphasia accompanied by acquired dyslexia in both languages. The main findings are an effect of imageability on reading in Turkish coincident with surface dyslexia in English and preserved nonword reading. BRB's acquired dyslexia suggests that damage to phonological representations might have a consequence for learning to read in Turkish. We argue that BRB's acquired dyslexia has a common locus in chronic underactivation of phonological representations in Turkish and English. Despite a common locus, reading problems manifest themselves differently according to properties of the script and the type of task. PMID:16107781

  12. Hysterosalpingographic features of cervical abnormalities: acquired structural anomalies.

    PubMed

    Zafarani, F; Ahmadi, F; Shahrzad, G

    2015-08-01

    Cervical abnormalities may be congenital or acquired. Congenital cervical structural anomalies are relatively uncommon, whereas acquired cervical abnormalities are commonly seen in gynaecology clinics. Acquired abnormalities of the cervix can cause cervical factor infertility and recurrent spontaneous abortion. Various imaging tools have been used for evaluation of the uterine cavity and fallopian tubes. Hysterosalpingography (HSG) is a quick and minimally invasive tool for evaluation of infertility that facilitates visualization of the inner surfaces of the uterine cavity and fallopian tubes, as well as the cervical canal and isthmus. The lesions of the uterine cervix show various imaging manifestations on HSG such as narrowing, dilatation, filling defects, irregularities and diverticular projections. This pictorial review describes and illustrates the hysterosalpingographic appearances of normal variants and acquired structural abnormalities of the cervix. Accurate diagnosis of such cases is considered essential for optimal treatment. The pathological findings and radiopathological correlation will be briefly discussed. PMID:26111269

  13. 33 CFR 211.2 - Authority to acquire real estate.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... false Authority to acquire real estate. 211.2 Section 211.2...THE ARMY, DEPARTMENT OF DEFENSE REAL ESTATE ACTIVITIES OF THE CORPS OF ENGINEERS...CONNECTION WITH CIVIL WORKS PROJECTS Real Estate; General § 211.2...

  14. 33 CFR 211.2 - Authority to acquire real estate.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... false Authority to acquire real estate. 211.2 Section 211.2...THE ARMY, DEPARTMENT OF DEFENSE REAL ESTATE ACTIVITIES OF THE CORPS OF ENGINEERS...CONNECTION WITH CIVIL WORKS PROJECTS Real Estate; General § 211.2...

  15. 33 CFR 211.2 - Authority to acquire real estate.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... false Authority to acquire real estate. 211.2 Section 211.2...THE ARMY, DEPARTMENT OF DEFENSE REAL ESTATE ACTIVITIES OF THE CORPS OF ENGINEERS...CONNECTION WITH CIVIL WORKS PROJECTS Real Estate; General § 211.2...

  16. An incident case of primary acquired pulmonary alveolar proteinosis.

    PubMed

    Vanderhelst, E; Bonella, F; Wissing, K; Verfaillie, G; Geers, C; Vincken, W

    2012-01-01

    This is a case of a primary acquired pulmonary alveolar proteinosis (PAP) in an asymptomatic patient, on the waiting list for kidney transplantation, confirmed on lung biopsy and by identifying anti-GM-CSF antibodies. PMID:22712171

  17. 33 CFR 211.2 - Authority to acquire real estate.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... false Authority to acquire real estate. 211.2 Section 211.2...THE ARMY, DEPARTMENT OF DEFENSE REAL ESTATE ACTIVITIES OF THE CORPS OF ENGINEERS...CONNECTION WITH CIVIL WORKS PROJECTS Real Estate; General § 211.2...

  18. Lower Motor Neuron Findings after Upper Motor Neuron Injury: Insights from Postoperative Supplementary Motor Area Syndrome

    PubMed Central

    Florman, Jeffrey E.; Duffau, Hugues; Rughani, Anand I.

    2013-01-01

    Hypertonia and hyperreflexia are classically described responses to upper motor neuron injury. However, acute hypotonia and areflexia with motor deficit are hallmark findings after many central nervous system insults such as acute stroke and spinal shock. Historic theories to explain these contradictory findings have implicated a number of potential mechanisms mostly relying on the loss of descending corticospinal input as the underlying etiology. Unfortunately, these simple descriptions consistently fail to adequately explain the pathophysiology and connectivity leading to acute hyporeflexia and delayed hyperreflexia that result from such insult. This article highlights the common observation of acute hyporeflexia after central nervous system insults and explores the underlying anatomy and physiology. Further, evidence for the underlying connectivity is presented and implicates the dominant role of supraspinal inhibitory influence originating in the supplementary motor area descending through the corticospinal tracts. Unlike traditional explanations, this theory more adequately explains the findings of postoperative supplementary motor area syndrome in which hyporeflexia motor deficit is observed acutely in the face of intact primary motor cortex connections to the spinal cord. Further, the proposed connectivity can be generalized to help explain other insults including stroke, atonic seizures, and spinal shock. PMID:23508473

  19. Biological movement increases acceptance of humanoid robots as human partners in motor interaction

    Microsoft Academic Search

    Aleksandra Kupferberg; Stefan Glasauer; Markus Huber; Markus Rickert; Alois Knoll; Thomas Brandt

    The automatic tendency to anthropomorphize our interaction partners and make use of experience acquired in earlier interaction\\u000a scenarios leads to the suggestion that social interaction with humanoid robots is more pleasant and intuitive than that with\\u000a industrial robots. An objective method applied to evaluate the quality of human–robot interaction is based on the phenomenon\\u000a of motor interference (MI). It claims

  20. Acquired hemophilia due to factor VIII inhibitors in 34 patients

    Microsoft Academic Search

    Philippe Bossi; Jean Cabane; Jacques Ninet; Robin Dhote; Thomas Hanslik; Olivier Chosidow; Chrystel Jouan-Flahault; Marie-Hélène Horellou; Francisque Leynadier; Eric Liozon; Jacques Pouchot; Jean Pierre Robin; Frédéric Sanderson; Annette Schaeffer; Didier Sicard; Frédérik Staikowsky; Bertrand Wechsler; Robert Zittoun

    1998-01-01

    BACKGROUND: Acquired hemophilia is a rare disease caused by the development of auto-antibodies against factor VIII.SUBJECTS AND METHODS: We studied the characteristics and outcomes of 34 patients (19 women and 15 men) with acquired hemophilia from 1980 to 1997.RESULTS: The mean age of the patients was 61 years (range, 22–93 years). An underlying disease was observed in 18 (53%) patients:

  1. Adult-Onset Acquired Partial Lipodystrophy Accompanied by Rheumatoid Arthritis

    PubMed Central

    Muto, Yusuke; Fujimura, Taku; Kakizaki, Aya; Tsuchiyama, Kenichiro; Kusakari, Yoshiyuki; Aiba, Setsuya

    2015-01-01

    Lipodystrophy is a group of metabolic disorders, possibly caused by autoimmune disease. In this report, we describe a case of adult-onset acquired partial lipodystrophy accompanied by rheumatoid arthritis without a family history. Interestingly, immunohistochemical staining revealed dense infiltration of IL-27-producing cells as well as MMP-7-and MMP-28-expressing cells, both of which have been reported to facilitate the development of autoimmune disease. Our present case might suggest possible mechanisms for acquired partial lipodystrophy. PMID:26034476

  2. Immunosuppression for acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2).

    PubMed

    Collins, Peter; Baudo, Francesco; Knoebl, Paul; Lévesque, Hervé; Nemes, László; Pellegrini, Fabio; Marco, Pascual; Tengborn, Lilian; Huth-Kühne, Angela

    2012-07-01

    Acquired hemophilia A (AHA) is an autoimmune disease caused by an autoantibody to factor VIII. Patients are at risk of severe and fatal hemorrhage until the inhibitor is eradicated, and guidelines recommend immunosuppression as soon as the diagnosis has been made. The optimal immunosuppressive regimen is unclear; therefore, data from 331 patients entered into the prospective EACH2 registry were analyzed. Steroids combined with cyclophosphamide resulted in more stable complete remission (70%), defined as inhibitor undetectable, factor VIII more than 70 IU/dL and immunosuppression stopped, than steroids alone (48%) or rituximab-based regimens (59%). Propensity score-matched analysis controlling for age, sex, factor VIII level, inhibitor titer, and underlying etiology confirmed that stable remission was more likely with steroids and cyclophosphamide than steroids alone (odds ratio = 3.25; 95% CI, 1.51-6.96; P < .003). The median time to complete remission was approximately 5 weeks for steroids with or without cyclophosphamide; rituximab-based regimens required approximately twice as long. Immunoglobulin administration did not improve outcome. Second-line therapy was successful in approximately 60% of cases that failed first-line therapy. Outcome was not affected by the choice of first-line therapy. The likelihood of achieving stable remission was not affected by underlying etiology but was influenced by the presenting inhibitor titer and FVIII level. PMID:22517903

  3. Management of bleeding in acquired hemophilia A: results from the European Acquired Haemophilia (EACH2) Registry.

    PubMed

    Baudo, Francesco; Collins, Peter; Huth-Kühne, Angela; Lévesque, Hervé; Marco, Pascual; Nemes, László; Pellegrini, Fabio; Tengborn, Lilian; Knoebl, Paul

    2012-07-01

    Acquired hemophilia A is a rare bleeding disorder caused by autoantibodies to coagulation FVIII. Bleeding episodes at presentation are spontaneous and severe in most cases. Optimal hemostatic therapy is controversial, and available data are from observational and retrospective studies only. The EACH2 registry, a multicenter, pan-European, Web-based database, reports current patient management. The aim was to assess the control of first bleeding episodes treated with a bypassing agent (rFVIIa or aPCC), FVIII, or DDAVP among 501 registered patients. Of 482 patients with one or more bleeding episodes, 144 (30%) received no treatment for bleeding; 31 were treated with symptomatic therapy only. Among 307 patients treated with a first-line hemostatic agent, 174 (56.7%) received rFVIIa, 63 (20.5%) aPCC, 56 (18.2%) FVIII, and 14 (4.6%) DDAVP. Bleeding was controlled in 269 of 338 (79.6%) patients treated with a first-line hemostatic agent or ancillary therapy alone. Propensity score matching was applied to allow unbiased comparison between treatment groups. Bleeding control was significantly higher in patients treated with bypassing agents versus FVIII/DDAVP (93.3% vs 68.3%; P = .003). Bleeding control was similar between rFVIIa and aPCC (93.0%; P = 1). Thrombotic events were reported in 3.6% of treated patients with a similar incidence between rFVIIa (2.9%) and aPCC (4.8%). PMID:22618709

  4. The Role of Self-Regulatory and Metacognitive Competence in the Motor Performance Difficulties of Children with Developmental Coordination Disorder: A Theoretical and Empirical Review

    Microsoft Academic Search

    Claire Sangster Joki?; David Whitebread

    2011-01-01

    Children with developmental coordination disorder (DCD) experience difficulty coping with everyday demands due to difficulties\\u000a in performing motor tasks. Recently, a cognitive learning paradigm has been applied to studying the nature of the problems\\u000a experienced by children with DCD, which assumes that these children have fewer cognitive and metacognitive skills with which\\u000a to acquire motor skills. However, despite the emergence

  5. The "Fusion EXPO" in Brussels

    NASA Astrophysics Data System (ADS)

    Ongena, Jef; van Oost, Guido; Paris, Pierre

    1997-11-01

    From the 22nd of october until the 28th of november, a fusion exhibit is being organized in the capital of Europe, Brussels. The aim of the exhibit is threefold : (i) give a feeling for the problem of our future energy supply (ii) show that fusion is possibly one of the most interesting of the very few options we have for our long term energy supply and (iii) to increase public awareness on fusion research. The exhibit deals mainly with magnetic fusion, with some part devoted to inertial fusion. Large photographs of different European fusion devices, maquettes of JET, Tore Supra etc..., parts of existing magnetic fusion experiments (antennas, limiters, etc...) should give the public an idea of what fusion research means in terms of real life. Especially school classes are invited and will be given guided tours of the exhibit. In particular also the members of the European Parliament are invited to the exhibit, and a special symposiom on fusion research will be organized to inform them on the need of this kind of research and the important benefits fusion has to offer over all other known energy sources. The poster will give a visual overview of the exhibit, next to providing some practical experience gathered until then. New materials for public use and especially prepared for this exhibit will be on display.

  6. Visuomotor learning by passive motor experience

    PubMed Central

    Sakamoto, Takashi; Kondo, Toshiyuki

    2015-01-01

    Humans can adapt to unfamiliar dynamic and/or kinematic transformations through the active motor experience. Recent studies of neurorehabilitation using robots or brain-computer interface (BCI) technology suggest that passive motor experience would play a measurable role in motor recovery, however our knowledge of passive motor learning is limited. To clarify the effects of passive motor experience on human motor learning, we performed arm reaching experiments guided by a robotic manipulandum. The results showed that the passive motor experience had an anterograde transfer effect on the subsequent motor execution, whereas no retrograde interference was confirmed in the ABA paradigm experiment. This suggests that the passive experience of the error between visual and proprioceptive sensations leads to the limited but actual compensation of behavior, although it is fragile and cannot be consolidated as a persistent motor memory. PMID:26029091

  7. LADAR and FLIR based sensor fusion for automatic target classification

    NASA Astrophysics Data System (ADS)

    Selzer, Fred; Gutfinger, Dan

    1988-01-01

    The purpose of this report is to show results of automatic target classification and sensor fusion for forward looking infrared (FLIR) and Laser Radar sensors. The sensor fusion data base was acquired from the Naval Weapon Center and consists of coregistered laser radar (LADAR) (range and reflectance image), FLIR (raw and preprocessed image), and TV. Using this data base, techniques are developed to extract relevant object edges from the FLIR and LADAR which are correlated to wireframe models. The resulting correlation coefficients from both the LADAR and FLIR are fused using either the Bayesian or the Dempster-Shafer combination method so as to provide a higher confidence target classification level output. Finally, to minimize the correlation process, the wireframe models are modified to reflect target range (size of target) and target orientation, which is extracted from the LADAR reflectance image.

  8. Computational fusion magnetohydrodynamics

    SciTech Connect

    Grimm, R.C.

    1984-01-01

    Simple magnetohydrodynamic models provide the framework for much of our understanding of the macroscopic behavior of magnetically confined laboratory plasmas. In even the simplest of models, however, the many different time and spatial scales, the multidimensionality, and the nonlinearity of the equations make finding solutions difficult. In realistic geometries obtaining quantitative results to aid our understanding, to interpret experiment, and to design new devices, involves the development of large scale numerical codes. During the past decade considerable effort has been extended in the fusion community to develop equilibrium, linear stability, and nonlinear time evolution codes in two and three dimensions, some of which have had a considerable impact on the fusion program. An overview of the various types of codes and numerical methods is given. Emphasis is on the spectrum of linear perturbations and ideal MHD stability, boundary layer methods and resistive MHD stability, and modeling of nonlinear, time evolution resistive MHD phenomena in tokamak configurations.

  9. ProFusion

    NSDL National Science Digital Library

    Originally developed by the University of Kansas Information Telecommunication and Technology Center, and School of Engineering DesignLab (see the July 25, 1997 Scout Report), ProFusion is a meta-search and "deep Web" search engine. Purchased by Intelliseek and fitted with a new interface, ProFusion allows users to search over 1,000 search sites, "including search engines, Web directories, discussion groups, news sources, online publications, and archives." Visitors can also perform targeted searches of vertical search sources, selecting which databases to query. Two other new features include an alert service that tracks changes to selected pages and notifies users by email and a Search Assistant that suggests results from search engine groups relevant to a query in addition to the general Web results. Worth a spin around the block.

  10. Registration and Fusion of Multiple Source Remotely Sensed Image Data

    NASA Technical Reports Server (NTRS)

    LeMoigne, Jacqueline

    2004-01-01

    Earth and Space Science often involve the comparison, fusion, and integration of multiple types of remotely sensed data at various temporal, radiometric, and spatial resolutions. Results of this integration may be utilized for global change analysis, global coverage of an area at multiple resolutions, map updating or validation of new instruments, as well as integration of data provided by multiple instruments carried on multiple platforms, e.g. in spacecraft constellations or fleets of planetary rovers. Our focus is on developing methods to perform fast, accurate and automatic image registration and fusion. General methods for automatic image registration are being reviewed and evaluated. Various choices for feature extraction, feature matching and similarity measurements are being compared, including wavelet-based algorithms, mutual information and statistically robust techniques. Our work also involves studies related to image fusion and investigates dimension reduction and co-kriging for application-dependent fusion. All methods are being tested using several multi-sensor datasets, acquired at EOS Core Sites, and including multiple sensors such as IKONOS, Landsat-7/ETM+, EO1/ALI and Hyperion, MODIS, and SeaWIFS instruments. Issues related to the coregistration of data from the same platform (i.e., AIRS and MODIS from Aqua) or from several platforms of the A-train (i.e., MLS, HIRDLS, OMI from Aura with AIRS and MODIS from Terra and Aqua) will also be considered.

  11. High Level Information Fusion (HLIF) with nested fusion loops

    NASA Astrophysics Data System (ADS)

    Woodley, Robert; Gosnell, Michael; Fischer, Amber

    2013-05-01

    Situation modeling and threat prediction require higher levels of data fusion in order to provide actionable information. Beyond the sensor data and sources the analyst has access to, the use of out-sourced and re-sourced data is becoming common. Through the years, some common frameworks have emerged for dealing with information fusion—perhaps the most ubiquitous being the JDL Data Fusion Group and their initial 4-level data fusion model. Since these initial developments, numerous models of information fusion have emerged, hoping to better capture the human-centric process of data analyses within a machine-centric framework. 21st Century Systems, Inc. has developed Fusion with Uncertainty Reasoning using Nested Assessment Characterizer Elements (FURNACE) to address challenges of high level information fusion and handle bias, ambiguity, and uncertainty (BAU) for Situation Modeling, Threat Modeling, and Threat Prediction. It combines JDL fusion levels with nested fusion loops and state-of-the-art data reasoning. Initial research has shown that FURNACE is able to reduce BAU and improve the fusion process by allowing high level information fusion (HLIF) to affect lower levels without the double counting of information or other biasing issues. The initial FURNACE project was focused on the underlying algorithms to produce a fusion system able to handle BAU and repurposed data in a cohesive manner. FURNACE supports analyst's efforts to develop situation models, threat models, and threat predictions to increase situational awareness of the battlespace. FURNACE will not only revolutionize the military intelligence realm, but also benefit the larger homeland defense, law enforcement, and business intelligence markets.

  12. Data fusion handoff within a federation of fusion systems

    NASA Astrophysics Data System (ADS)

    Shea, Peter J.; Roskamp, Bryce

    2007-09-01

    As the military continues to move forward with an increased number of sensor and fusion systems, it becomes necessary for these systems to be able to communicate efficiently and effectively. In these environments there are multiple sensor and fusion systems that in the past have operated independently of one another. As an increasing number of systems become available, eventually an overlap in the coverage area occurs between these fusion systems. This results in a need for coordination between these semi-autonomous fusion systems. Short of a complete redesign of all the fusion systems, a solution is required to address the handoff of data between these systems. The primary goal of this paper is to describe a data fusion handoff capability that is able to augment these existing systems. This is accomplished by the use of a Handoff Manager that is added to each fusion system. The Handoff Manager is responsible for developing a global representation the track information displayed onboard its own fusion system that is common with the other members of the federation of fusion systems. This is accomplished by using a global track numbering scheme that requires communication and adjudication between the multiple Handoff Manager components that are present on the different fusion systems within the federation. This paper will define the data fusion handoff problem and describe our approach for handling the data fusion handoff problem within the context of overlapping and non-overlapping sensor environments. We will conclude with a discussion of results for a sample problem and of the path forward.

  13. Motor influences on judgment: Motor and cognitive integration.

    PubMed

    Mullet, Etienne; Cretenet, Joël; Dru, Vincent

    2014-02-01

    Performing motor behaviours (arm flexion vs. extension) that correspond also to lateralized peripheral activations (left vs. right side) of the motivational systems of approach versus avoidance have been previously shown to impact cognitive performance and judgment. Three experiments are reported that examined the combined effect of these variables, as a kind of motor integration, on the implementation of information integration rules in various judgment tasks: judging of a person's attractiveness from personality information, judging of the severity of health risk from alcohol and tobacco intake, and attributing blame to a perpetrator from information as to intent and severity of harm done. It was found that the congruence between these motivational activations consistently influenced the use of interactive information integration rules, compared to additive ones. This set of findings showed that cognitive rules might also be embodied. Motor integration affects cognitive integration in judgment. PMID:24387097

  14. Sensor data fusion

    Microsoft Academic Search

    Louis-françois Pau

    1988-01-01

    This paper reviews some knowledge representation approaches devoted to the sensor fusion problem, as encountered whenever images, signals, text must be combined to provide the input to a controller or to an inference procedure. The basic steps involved in the derivation of the knowledge representation scheme, are:(A)locate a representation, based on exogeneous context information(B)compare two representations to find out if

  15. Pulsed High Density Fusion

    NASA Astrophysics Data System (ADS)

    Slough, John

    2000-10-01

    Based on FRC acceleration experiments, together with confinement scaling observed in past FRC experiments, a method has been determined by which an FRC can be compressed to high density and brought to ignition conditions in a rapid, repetitive manner. This regime is referred to as the Pulsed High Density (PHD) regime of MFE. Unlike MTF, the upper boundary of this regime remains below the density limit imposed by material strength limitations. Data from various FRC experiments yield a scaling with size and density such that at a density of 10^24 m-3, a fusion gain > 1 can be achieved at a radius ~ 1 cm. The energy necessary for burn is transferred to the FRC in the form of translational energy, which is produced by an inductive magnetized plasma accelerator (IMPAC) that is capable of repetitive pulsing. The simplicity of this approach to fusion lies in the fact that the directed energy of the FRC mass is much greater than the FRC internal energy, so that the confining magnetic fields, as well as accelerating fields, need to be no greater than required to contain the low-pressure FRC generated in the source coil ( ~ 0.4 T). The conversion of the FRC directed energy into thermal energy occurs only after the FRC has reached the burn chamber where the FRC is slowed and compressed to fusion conditions. The goal of a concept exploration experiment would be the construction of an IMPAC device capable of producing a FRC plasma where all key parameters can be brought to within an order of magnitude of that required for a Q ~1 fusion burn. Details of such an experiment will be discussed.

  16. Fusion development and technology

    SciTech Connect

    Montgomery, D.B.

    1992-01-01

    This report discusses the following: superconducting magnet technology; high field superconductors; advanced magnetic system and divertor development; poloidal field coils; gyrotron development; commercial reactor studies--aries; ITER physics: alpha physics and alcator R D for ITER; lower hybrid current drive and heating in the ITER device; ITER superconducting PF scenario and magnet analysis; ITER systems studies; and safety, environmental and economic factors in fusion development.

  17. (Fusion energy research)

    SciTech Connect

    Phillips, C.A. (ed.)

    1988-01-01

    This report discusses the following topics: principal parameters achieved in experimental devices (FY88); tokamak fusion test reactor; Princeton beta Experiment-Modification; S-1 Spheromak; current drive experiment; x-ray laser studies; spacecraft glow experiment; plasma deposition and etching of thin films; theoretical plasma; tokamak modeling; compact ignition tokamak; international thermonuclear experimental reactor; Engineering Department; Project Planning and Safety Office; quality assurance and reliability; and technology transfer.

  18. Tokamak fusion power reactors

    Microsoft Academic Search

    W. M. Stacey Jr.; M. A. Abdou

    1978-01-01

    The major parameters and corresponding economic characteristics of a representative class of commercial Tokamak fusion power reactors are examined as a function of four major design parameters: plasma beta-t, toroidal magnetic field strength, first-wall lifetime, and power output. It is shown that for beta-t greater than or equal to 0.06, the minimum cost of energy is obtained for toroidal field

  19. Cosmic Data Fusion

    Microsoft Academic Search

    S. L. Bridle

    2005-01-01

    I will discuss our work on cosmic data fusion: the comparison and combination of various cosmological data sets to estimate cosmological parameters. We find good agreement on cosmological parameters between galaxy velocities, CMB and Type 1a supernovae with 95 per cent confidence limits 0.64 < h < 0.86, 0.17 < &Omegam < 0.39 and 0.98 < sigma8 < 1.37. We

  20. Fusion Policy Advisory Committee FINAL REPORT

    E-print Network

    Fusion Policy Advisory Committee (FPAC) FINAL REPORT September 1990 Report of the Technical Panel on Magnetic Fusion of the Energy Research Advisory Board Washington, D .C. 20585 #12;#12;Fusion Policy of your Fusion Policy Advisory Committee. It presents a fusion policy that the Committee believes

  1. Anodal transcranial direct current stimulation over premotor cortex facilitates observational learning of a motor sequence.

    PubMed

    Wade, Stephanie; Hammond, Geoff

    2015-06-01

    Motor skills, including complex movement sequences, can be acquired by observing a model without physical practice of the skill, a phenomenon known as observational learning. Observational learning of motor skills engages the same memory substrate as physical practice, and is thought to be mediated by the action observation network, a bilateral fronto-parietal circuit with mirror-like properties. We examined the effects of anodal transcranial direct current stimulation (tDCS) over premotor cortex, a key node of the action observation network, on observational learning of a serial response time task. Results showed that anodal tDCS during observation of the to-be-learned sequence facilitated reaction times in the subsequent behavioral test. The study provides evidence that increasing excitability of the action observation network during observation can facilitate later motor skill acquisition. PMID:25865458

  2. Stabilized Spheromak Fusion Reactors

    SciTech Connect

    Fowler, T

    2007-04-03

    The U.S. fusion energy program is focused on research with the potential for studying plasmas at thermonuclear temperatures, currently epitomized by the tokamak-based International Thermonuclear Experimental Reactor (ITER) but also continuing exploratory work on other plasma confinement concepts. Among the latter is the spheromak pursued on the SSPX facility at LLNL. Experiments in SSPX using electrostatic current drive by coaxial guns have now demonstrated stable spheromaks with good heat confinement, if the plasma is maintained near a Taylor state, but the anticipated high current amplification by gun injection has not yet been achieved. In future experiments and reactors, creating and maintaining a stable spheromak configuration at high magnetic field strength may require auxiliary current drive using neutral beams or RF power. Here we show that neutral beam current drive soon to be explored on SSPX could yield a compact spheromak reactor with current drive efficiency comparable to that of steady state tokamaks. Thus, while more will be learned about electrostatic current drive in coming months, results already achieved in SSPX could point to a productive parallel development path pursuing auxiliary current drive, consistent with plans to install neutral beams on SSPX in the near future. Among possible outcomes, spheromak research could also yield pulsed fusion reactors at lower capital cost than any fusion concept yet proposed.

  3. COLLABORATIVE: FUSION SIMULATION PROGRAM

    SciTech Connect

    Chang, Choong Seock

    2012-06-05

    New York University, Courant Institute of Mathematical Sciences, participated in the ���¢��������Fusion Simulation Program (FSP) Planning Activities���¢������� [http://www.pppl.gov/fsp], with C.S. Chang as the institutional PI. FSP���¢��������s mission was to enable scientific discovery of important new plasma phenomena with associated understanding that emerges only upon integration. This requires developing a predictive integrated simulation capability for magnetically-confined fusion plasmas that are properly validated against experiments in regimes relevant for producing practical fusion energy. Specific institutional goal of the New York University was to participate in the planning of the edge integrated simulation, with emphasis on the usage of large scale HPCs, in connection with the SciDAC CPES project which the PI was leading. New York University successfully completed its mission by participating in the various planning activities, including the edge physics integration, the edge science drivers, and the mathematical verification. The activity resulted in the combined report that can be found in http://www.pppl.gov/fsp/Overview.html. Participation and presentations as part of this project are listed in a separation file.

  4. Motor "dexterity"?: Evidence that left hemisphere lateralization of motor circuit connectivity is associated with better motor performance in children.

    PubMed

    Barber, Anita D; Srinivasan, Priti; Joel, Suresh E; Caffo, Brian S; Pekar, James J; Mostofsky, Stewart H

    2012-01-01

    Motor control relies on well-established motor circuits, which are critical for typical child development. Although many imaging studies have examined task activation during motor performance, none have examined the relationship between functional intrinsic connectivity and motor ability. The current study investigated the relationship between resting state functional connectivity within the motor network and motor performance assessment outside of the scanner in 40 typically developing right-handed children. Better motor performance correlated with greater left-lateralized (mean left hemisphere-mean right hemisphere) motor circuit connectivity. Speed, rhythmicity, and control of movements were associated with connectivity within different individual region pairs: faster speed was associated with more left-lateralized putamen-thalamus connectivity, less overflow with more left-lateralized supplementary motor-primary motor connectivity, and less dysrhythmia with more left-lateralized supplementary motor-anterior cerebellar connectivity. These findings suggest that for right-handed children, superior motor development depends on the establishment of left-hemisphere dominance in intrinsic motor network connectivity. PMID:21613469

  5. Three phase AC motor controller

    DOEpatents

    Vuckovich, Michael (Elizabeth, PA); Wright, Maynard K. (Bethel Park, PA); Burkett, John P. (South Huntington Township, Westmoreland County, PA)

    1984-03-20

    A motor controller for a three phase AC motor (10) which is adapted to operate bidirectionally from signals received either from a computer (30) or a manual control (32). The controller is comprised of digital logic circuit means which implement a forward and reverse command signal channel (27, 29) for the application of power through the forward and reverse power switching relays (16, 18, 20, 22). The digital logic elements are cross coupled to prevent activation of both channels simultaneously and each includes a plugging circuit (65, 67) for stopping the motor upon the removal of control signal applied to one of the two channels (27, 29) for a direction of rotation desired. Each plugging circuit (65, 67) includes a one-shot pulse signal generator (88, 102) which outputs a single pulse signal of predetermined pulsewidth which is adapted to inhibit further operation of the application of power in the channel which is being activated and to apply a reversal command signal to the other channel which provides a reversed phase application of power to the motor for a period defined by the pulse-width output of the one-shot signal generator to plug the motor (10) which will then be inoperative until another rotational command signal is applied to either of the two channels.

  6. Cargo transport by several motors

    E-print Network

    Zhang, Yunxin

    2010-01-01

    In cells, organelles and vesicles are usually transported by cooperation of several motor proteins, including plus-end directed motor kinesin and minus-end directed motor dynein. Many biophysical models have been constructed to understand the mechanism of this motion. However, so far, the basic principle about it remains unclosed. In this paper, based on the recent experimental results and existing theoretical models, a spider-like model is provided. In this model, each motor is regarded as a bead-spring system. The bead can bind to or unbind from the track stochastically, and step forward or backward with fixed step size L and force dependent transition rates. The spring connects the bead to cargo tightly. At any time, the position of cargo is determined by force balance condition. The obvious characteristics of our model are that, the motors interact with each other and they do not share the external load equally. Our results indicate, the stall force of cargo, under which the mean velocity of cargo vanishe...

  7. Acquisition and improvement of human motor skills: Learning through observation and practice

    NASA Technical Reports Server (NTRS)

    Iba, Wayne

    1991-01-01

    Skilled movement is an integral part of the human existence. A better understanding of motor skills and their development is a prerequisite to the construction of truly flexible intelligent agents. We present MAEANDER, a computational model of human motor behavior, that uniformly addresses both the acquisition of skills through observation and the improvement of skills through practice. MAEANDER consists of a sensory-effector interface, a memory of movements, and a set of performance and learning mechanisms that let it recognize and generate motor skills. The system initially acquires such skills by observing movements performed by another agent and constructing a concept hierarchy. Given a stored motor skill in memory, MAEANDER will cause an effector to behave appropriately. All learning involves changing the hierarchical memory of skill concepts to more closely correspond to either observed experience or to desired behaviors. We evaluated MAEANDER empirically with respect to how well it acquires and improves both artificial movement types and handwritten script letters from the alphabet. We also evaluate MAEANDER as a psychological model by comparing its behavior to robust phenomena in humans and by considering the richness of the predictions it makes.

  8. Differential Cargo Mobilisation within Weibel-Palade Bodies after Transient Fusion with the Plasma Membrane

    PubMed Central

    Kiskin, Nikolai I.; Babich, Victor; Knipe, Laura; Hannah, Matthew J.; Carter, Tom

    2014-01-01

    Inflammatory chemokines can be selectively released from Weibel-Palade bodies (WPBs) during kiss-and-run exocytosis. Such selectivity may arise from molecular size filtering by the fusion pore, however differential intra-WPB cargo re-mobilisation following fusion-induced structural changes within the WPB may also contribute to this process. To determine whether WPB cargo molecules are differentially re-mobilised, we applied FRAP to residual post-fusion WPB structures formed after transient exocytosis in which some or all of the fluorescent cargo was retained. Transient fusion resulted in WPB collapse from a rod to a spheroid shape accompanied by substantial swelling (>2 times by surface area) and membrane mixing between the WPB and plasma membranes. Post-fusion WPBs supported cumulative WPB exocytosis. To quantify diffusion inside rounded organelles we developed a method of FRAP analysis based on image moments. FRAP analysis showed that von Willebrand factor-EGFP (VWF-EGFP) and the VWF-propolypeptide-EGFP (Pro-EGFP) were immobile in post-fusion WPBs. Because Eotaxin-3-EGFP and ssEGFP (small soluble cargo proteins) were largely depleted from post-fusion WPBs, we studied these molecules in cells preincubated in the weak base NH4Cl which caused WPB alkalinisation and rounding similar to that produced by plasma membrane fusion. In these cells we found a dramatic increase in mobilities of Eotaxin-3-EGFP and ssEGFP that exceeded the resolution of our method (?2.4 µm2/s mean). In contrast, the membrane mobilities of EGFP-CD63 and EGFP-Rab27A in post-fusion WPBs were unchanged, while P-selectin-EGFP acquired mobility. Our data suggest that selective re-mobilisation of chemokines during transient fusion contributes to selective chemokine secretion during transient WPB exocytosis. Selective secretion provides a mechanism to regulate intravascular inflammatory processes with reduced risk of thrombosis. PMID:25233365

  9. Evaluation of preoperative high magnetic field motor functional MRI (3 Tesla) in glioma patients by navigated electrocortical stimulation and postoperative outcome

    PubMed Central

    Roessler, K; Donat, M; Lanzenberger, R; Novak, K; Geissler, A; Gartus, A; Tahamtan, A; Milakara, D; Czech, T; Barth, M; Knosp, E; Beisteiner, R

    2005-01-01

    Objectives: The validity of 3 Tesla motor functional magnetic resonance imaging (fMRI) in patients with gliomas involving the primary motor cortex was investigated by intraoperative navigated motor cortex stimulation (MCS). Methods: Twenty two patients (10 males, 12 females, mean age 39 years, range 10–65 years) underwent preoperative fMRI studies, performing motor tasks including hand, foot, and mouth movements. A recently developed high field clinical fMRI technique was used to generate pre-surgical maps of functional high risk areas defining a motor focus. Motor foci were tested for validity by intraoperative motor cortex stimulation (MCS) employing image fusion and neuronavigation. Clinical outcome was assessed using the Modified Rankin Scale. Results: FMRI motor foci were successfully detected in all patients preoperatively. In 17 of 22 patients (77.3%), a successful stimulation of the primary motor cortex was possible. All 17 correlated patients showed 100% agreement on MCS and fMRI motor focus within 10 mm. Technical problems during stimulation occurred in three patients (13.6%), no motor response was elicited in two (9.1%), and MCS induced seizures occurred in three (13.6%). Combined fMRI and MCS mapping results allowed large resections in 20 patients (91%) (gross total in nine (41%), subtotal in 11 (50%)) and biopsy in two patients (9%). Pathology revealed seven low grade and 15 high grade gliomas. Mild to moderate transient neurological deterioration occurred in six patients, and a severe hemiparesis in one. All patients recovered within 3 months (31.8% transient, 0% permanent morbidity). Conclusions: The validation of clinically optimised high magnetic field motor fMRI confirms high reliability as a preoperative and intraoperative adjunct in glioma patients selected for surgery within or adjacent to the motor cortex. PMID:16024896

  10. Effect of instructive visual stimuli on neurofeedback training for motor imagery-based brain-computer interface.

    PubMed

    Kondo, Toshiyuki; Saeki, Midori; Hayashi, Yoshikatsu; Nakayashiki, Kosei; Takata, Yohei

    2014-11-13

    Event-related desynchronization (ERD) of the electroencephalogram (EEG) from the motor cortex is associated with execution, observation, and mental imagery of motor tasks. Generation of ERD by motor imagery (MI) has been widely used for brain-computer interfaces (BCIs) linked to neuroprosthetics and other motor assistance devices. Control of MI-based BCIs can be acquired by neurofeedback training to reliably induce MI-associated ERD. To develop more effective training conditions, we investigated the effect of static and dynamic visual representations of target movements (a picture of forearms or a video clip of hand grasping movements) during the BCI neurofeedback training. After 4 consecutive training days, the group that performed MI while viewing the video showed significant improvement in generating MI-associated ERD compared with the group that viewed the static image. This result suggests that passively observing the target movement during MI would improve the associated mental imagery and enhance MI-based BCIs skills. PMID:25467185

  11. Neural substrates underlying motor skill learning in chronic hemiparetic stroke patients

    PubMed Central

    Lefebvre, Stéphanie; Dricot, Laurence; Laloux, Patrice; Gradkowski, Wojciech; Desfontaines, Philippe; Evrard, Frédéric; Peeters, André; Jamart, Jacques; Vandermeeren, Yves

    2015-01-01

    Motor skill learning is critical in post-stroke motor recovery, but little is known about its underlying neural substrates. Recently, using a new visuomotor skill learning paradigm involving a speed/accuracy trade-off in healthy individuals we identified three subpopulations based on their behavioral trajectories: fitters (in whom improvement in speed or accuracy coincided with deterioration in the other parameter), shifters (in whom speed and/or accuracy improved without degradation of the other parameter), and non-learners. We aimed to identify the neural substrates underlying the first stages of motor skill learning in chronic hemiparetic stroke patients and to determine whether specific neural substrates were recruited in shifters versus fitters. During functional magnetic resonance imaging (fMRI), 23 patients learned the visuomotor skill with their paretic upper limb. In the whole-group analysis, correlation between activation and motor skill learning was restricted to the dorsal prefrontal cortex of the damaged hemisphere (DLPFCdamh: r = ?0.82) and the dorsal premotor cortex (PMddamh: r = 0.70); the correlations was much lesser (?0.16 < r > 0.25) in the other regions of interest. In a subgroup analysis, significant activation was restricted to bilateral posterior parietal cortices of the fitters and did not correlate with motor skill learning. Conversely, in shifters significant activation occurred in the primary sensorimotor cortexdamh and supplementary motor areadamh and in bilateral PMd where activation changes correlated significantly with motor skill learning (r = 0.91). Finally, resting-state activity acquired before learning showed a higher functional connectivity in the salience network of shifters compared with fitters (qFDR < 0.05). These data suggest a neuroplastic compensatory reorganization of brain activity underlying the first stages of motor skill learning with the paretic upper limb in chronic hemiparetic stroke patients, with a key role of bilateral PMd. PMID:26089787

  12. Chase Delphi study on fusion

    NASA Astrophysics Data System (ADS)

    Meyer, A. J.

    1982-10-01

    The ongoing Chase Delphi study of fusion power has employed a panel of over 100 experts from 13 countries. The use of fusion for synfuel production was emphasized. The panelists believed that the length of time to successful demonstrations and commercialization of fusion could be substantially reduced over current estimates given optimal funding, and that a hydrocarbon producing reactor is feasible with minimal adverse impact on the environment.

  13. Directions for improved fusion reactors

    Microsoft Academic Search

    R. A. Krakowski; R. L. Miller; J. G. Delene

    1986-01-01

    Conceptual fusion reactor studies over the past 10 to 15 years have projected systems that may be too large, complex, and costly to be of commercial interest. One main direction for improved fusion reactors points towards smaller, higher-power-density approaches. First-order economic issues (i.e., unit direct cost and cost of electricity) are used to support the need for more compact fusion

  14. Sensor fusion for synthetic vision

    NASA Technical Reports Server (NTRS)

    Pavel, M.; Larimer, J.; Ahumada, A.

    1991-01-01

    Display methodologies are explored for fusing images gathered by millimeter wave sensors with images rendered from an on-board terrain data base to facilitate visually guided flight and ground operations in low visibility conditions. An approach to fusion based on multiresolution image representation and processing is described which facilitates fusion of images differing in resolution within and between images. To investigate possible fusion methods, a workstation-based simulation environment is being developed.

  15. Remote control for motor vehicle

    NASA Technical Reports Server (NTRS)

    Johnson, Dale R. (Inventor); Ciciora, John A. (Inventor)

    1984-01-01

    A remote controller is disclosed for controlling the throttle, brake and steering mechanism of a conventional motor vehicle, with the remote controller being particularly advantageous for use by severely handicapped individuals. The controller includes a remote manipulator which controls a plurality of actuators through interfacing electronics. The remote manipulator is a two-axis joystick which controls a pair of linear actuators and a rotary actuator, with the actuators being powered by electric motors to effect throttle, brake and steering control of a motor vehicle adapted to include the controller. The controller enables the driver to control the adapted vehicle from anywhere in the vehicle with one hand with minimal control force and range of motion. In addition, even though a conventional vehicle is adapted for use with the remote controller, the vehicle may still be operated in the normal manner.

  16. Rapid fusion between mesenchymal stem cells and cardiomyocytes yields electrically active, non-contractile hybrid cells

    PubMed Central

    Shadrin, Ilya Y.; Yoon, Woohyun; Li, Liqing; Shepherd, Neal; Bursac, Nenad

    2015-01-01

    Cardiac cell therapies involving bone marrow-derived human mesenchymal stem cells (hMSCs) have shown promising results, although their mechanisms of action are still poorly understood. Here, we investigated direct interactions between hMSCs and cardiomyocytes in vitro. Using a genetic Ca2+ indicator gCaMP3 to efficiently label hMSCs in co-cultures with neonatal rat ventricular myocytes (NRVMs), we determined that 25–40% of hMSCs (from 4 independent donors) acquired periodic Ca2+ transients and cardiac markers through spontaneous fusion with NRVMs. Sharp electrode and voltage-clamp recordings in fused cells showed action potential properties and Ca2+ current amplitudes in between those of non-fused hMSCs and NRVMs. Time-lapse video-microscopy revealed the first direct evidence of active fusion between hMSCs and NRVMs within several hours of co-culture. Application of blebbistatin, nifedipine or verapamil caused complete and reversible inhibition of fusion, suggesting potential roles for actomyosin bridging and Ca2+ channels in the fusion process. Immunostaining for Cx43, Ki67, and sarcomeric ?-actinin showed that fused cells remain strongly coupled to surrounding NRVMs, but downregulate sarcomeric structures over time, acquiring a non-proliferative and non-contractile phenotype. Overall, these results describe the phenotype and mechanisms of hybrid cell formation via fusion of hMSCs and cardiomyocytes with potential implications for cardiac cell therapy. PMID:26159124

  17. Rapid fusion between mesenchymal stem cells and cardiomyocytes yields electrically active, non-contractile hybrid cells.

    PubMed

    Shadrin, Ilya Y; Yoon, Woohyun; Li, Liqing; Shepherd, Neal; Bursac, Nenad

    2015-01-01

    Cardiac cell therapies involving bone marrow-derived human mesenchymal stem cells (hMSCs) have shown promising results, although their mechanisms of action are still poorly understood. Here, we investigated direct interactions between hMSCs and cardiomyocytes in vitro. Using a genetic Ca(2+) indicator gCaMP3 to efficiently label hMSCs in co-cultures with neonatal rat ventricular myocytes (NRVMs), we determined that 25-40% of hMSCs (from 4 independent donors) acquired periodic Ca(2+) transients and cardiac markers through spontaneous fusion with NRVMs. Sharp electrode and voltage-clamp recordings in fused cells showed action potential properties and Ca(2+) current amplitudes in between those of non-fused hMSCs and NRVMs. Time-lapse video-microscopy revealed the first direct evidence of active fusion between hMSCs and NRVMs within several hours of co-culture. Application of blebbistatin, nifedipine or verapamil caused complete and reversible inhibition of fusion, suggesting potential roles for actomyosin bridging and Ca(2+) channels in the fusion process. Immunostaining for Cx43, Ki67, and sarcomeric ?-actinin showed that fused cells remain strongly coupled to surrounding NRVMs, but downregulate sarcomeric structures over time, acquiring a non-proliferative and non-contractile phenotype. Overall, these results describe the phenotype and mechanisms of hybrid cell formation via fusion of hMSCs and cardiomyocytes with potential implications for cardiac cell therapy. PMID:26159124

  18. Acute lower motor neuron tetraparesis.

    PubMed

    Añor, Sònia

    2014-11-01

    Flaccid nonambulatory tetraparesis or tetraplegia is an infrequent neurologic presentation; it is characteristic of neuromuscular disease (lower motor neuron [LMN] disease) rather than spinal cord disease. Paresis beginning in the pelvic limbs and progressing to the thoracic limbs resulting in flaccid tetraparesis or tetraplegia within 24 to 72 hours is a common presentation of peripheral nerve or neuromuscular junction disease. Complete body flaccidity develops with severe decrease or complete loss of spinal reflexes in pelvic and thoracic limbs. Animals with acute generalized LMN tetraparesis commonly show severe motor dysfunction in all limbs and severe generalized weakness in all muscles. PMID:25441630

  19. Homopolar motor with dual rotors

    DOEpatents

    Hsu, John S. (Oak Ridge, TN)

    1998-01-01

    A homopolar motor (10) has a field rotor (15) mounted on a frame (11) for rotation in a first rotational direction and for producing an electromagnetic field, and an armature rotor (17) mounted for rotation on said frame (11) within said electromagnetic field and in a second rotational direction counter to said first rotational direction of said field rotor (15). The two rotors (15, 17) are coupled through a 1:1 gearing mechanism (19), so as to travel at the same speed but in opposite directions. This doubles the output voltage and output power, as compared to a motor in which only the armature is rotated. Several embodiments are disclosed.

  20. The Advanced Solid Rocket Motor

    NASA Technical Reports Server (NTRS)

    Mitchell, Royce E.

    1992-01-01

    The Advanced Solid Rocket Motor will utilize improved design features and automated manufacturing methods to produce an inherently safer propulsive system for the Space Shuttle and future launch systems. This second-generation motor will also provide an additional 12,000 pounds of payload to orbit, enhancing the utility and efficiency of the Shuttle system. The new plant will feature strip-wound, asbestos-free insulation; propellant continuous mixing and casting; and extensive robotic systems. Following a series of static tests at the Stennis Space Center, MS flights are targeted to begin in early 1997.