Sample records for act ipa assignment

  1. IPAS Implementation Handbook

    ERIC Educational Resources Information Center

    Brooks, D. Christopher

    2014-01-01

    While the use of analytics to promote student success is gaining in popularity, basic questions about what IPAS is and the issues institutions face during implementation and integration. The "IPAS Implementation Handbook" catalogs the experiences, observations, and practical advice from 19 institutions engaged in IPAS implementation…

  2. Formularity: Software for Automated Formula Assignment of Natural and Other Organic Matter from Ultrahigh-Resolution Mass Spectra.

    PubMed

    Tolić, Nikola; Liu, Yina; Liyu, Andrey; Shen, Yufeng; Tfaily, Malak M; Kujawinski, Elizabeth B; Longnecker, Krista; Kuo, Li-Jung; Robinson, Errol W; Paša-Tolić, Ljiljana; Hess, Nancy J

    2017-12-05

    Ultrahigh resolution mass spectrometry, such as Fourier transform ion cyclotron resonance mass spectrometry (FT ICR MS), can resolve thousands of molecular ions in complex organic matrices. A Compound Identification Algorithm (CIA) was previously developed for automated elemental formula assignment for natural organic matter (NOM). In this work, we describe software Formularity with a user-friendly interface for CIA function and newly developed search function Isotopic Pattern Algorithm (IPA). While CIA assigns elemental formulas for compounds containing C, H, O, N, S, and P, IPA is capable of assigning formulas for compounds containing other elements. We used halogenated organic compounds (HOC), a chemical class that is ubiquitous in nature as well as anthropogenic systems, as an example to demonstrate the capability of Formularity with IPA. A HOC standard mix was used to evaluate the identification confidence of IPA. Tap water and HOC spike in Suwannee River NOM were used to assess HOC identification in complex environmental samples. Strategies for reconciliation of CIA and IPA assignments were discussed. Software and sample databases with documentation are freely available.

  3. Formularity: Software for Automated Formula Assignment of Natural and Other Organic Matter from Ultrahigh-Resolution Mass Spectra

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tolić, Nikola; Liu, Yina; Liyu, Andrey

    Ultrahigh-resolution mass spectrometry, such as Fourier transform ion-cyclotron resonance mass spectrometry (FT-ICR MS), can resolve thousands of molecular ions in complex organic matrices. A Compound Identification Algorithm (CIA) was previously developed for automated elemental formula assignment for natural organic matter (NOM). In this work we describe a user friendly interface for CIA, titled Formularity, which includes an additional functionality to perform search of formulas based on an Isotopic Pattern Algorithm (IPA). While CIA assigns elemental formulas for compounds containing C, H, O, N, S, and P, IPA is capable of assigning formulas for compounds containing other elements. We used halogenatedmore » organic compounds (HOC), a chemical class that is ubiquitous in nature as well as anthropogenic systems, as an example to demonstrate the capability of Formularity with IPA. A HOC standard mix was used to evaluate the identification confidence of IPA. The HOC spike in NOM and tap water were used to assess HOC identification in natural and anthropogenic matrices. Strategies for reconciliation of CIA and IPA assignments are discussed. Software and sample databases with documentation are freely available from the PNNL OMICS software repository https://omics.pnl.gov/software/formularity.« less

  4. Shigella IpaB and IpaD displayed on L. lactis bacterium-like particles induce protective immunity in adult and infant mice

    PubMed Central

    Heine, Shannon J.; Franco-Mahecha, Olga L.; Chen, Xiaotong; Choudhari, Shyamal; Blackwelder, William C.; van Roosmalen, Maarten L.; Leenhouts, Kees; Picking, Wendy L.; Pasetti, Marcela F.

    2015-01-01

    Shigella spp. are among the enteric pathogens with the highest attributable incidence of moderate-to-severe diarrhea in children under 5 years of age living in endemic areas. There are no vaccines available to prevent this disease. In this work, we investigated a new Shigella vaccine concept consisting of non-living, self-adjuvanted, Lactococcus lactis bacterium-like particles (BLP) displaying Shigella invasion plasmid antigen (Ipa) B and IpaD and examined its immunogenicity and protective efficacy in adult and newborn/infant mice immunized via the nasal route. Unique advantages of this approach include the potential for broad protection due to the highly conserved structure of the Ipas and the safety and practicality of a probiotic-based mucosal/adjuvant delivery platform. Immunization of adult mice with BLP-IpaB and BLP-IpaD (BLP-IpaB/D) induced high levels of Ipa-specific serum IgG and stool IgA in a dose-dependent manner. Immune responses and protection were enhanced by BLP delivery. Vaccine-induced serum antibodies exhibited opsonophagocytic and cytotoxic neutralizing activity, and IpaB/D IgG titers correlated with increased survival post-challenge. Ipa-specific antibody secreting cells were detected in nasal tissue and lungs, as well as IgG in bronchoalveolar lavage. Bone marrow cells produced IpaB/D-specific antibodies and contributed to protection after adoptive transfer. The BLP-IpaB/D vaccine conferred 90% and 80% protection against S. flexneri and S. sonnei, respectively. Mice immunized with BLP-IpaB/D as newborns also developed IpaB and IpaD serum antibodies; 90% were protected against S. flexneri and 44% against S. sonnei. The BLP-IpaB/D vaccine is a promising candidate for safe, practical and potentially effective immunization of children against shigellosis. PMID:25776843

  5. Evaluation of immunogenicity and protective efficacy of orally delivered Shigella type III secretion system proteins IpaB and IpaD

    PubMed Central

    Heine, Shannon J.; Diaz-McNair, Jovita; Martinez-Becerra, Francisco J.; Choudhari, Shyamal P.; Clements, John D.; Picking, Wendy L.; Pasetti, Marcela F.

    2013-01-01

    Shigella spp. are food- and water-borne pathogens that cause shigellosis, a severe diarrheal and dysenteric disease that is associated with a high morbidity and mortality in resource-poor countries. No licensed vaccine is available to prevent shigellosis. We have recently demonstrated that Shigella invasion plasmid antigens (Ipas), IpaB and IpaD, which are components of the bacterial type III secretion system (TTSS), can prevent infection in a mouse model of intranasal immunization and lethal pulmonary challenge. Because they are conserved across Shigella spp. and highly immunogenic, these proteins are excellent candidates for a cross-protective vaccine. Ideally, such a vaccine could be administered to humans orally to induce mucosal and systemic immunity. In this study, we investigated the immunogenicity and protective efficacy of Shigella IpaB and IpaD administered orally with a double mutant of the Escherichia coli heat labile toxin (dmLT) as a mucosal adjuvant. We characterized the immune responses induced by oral vs. intranasal immunization and the protective efficacy using a mouse pulmonary infection model. Serum IgG and fecal IgA against IpaB were induced after oral immunization. These responses, however, were lower than those obtained after intranasal immunization despite a 100-fold dosage increase. The level of protection induced by oral immunization with IpaB and IpaD was 40%, while intranasal immunization resulted in 90% protective efficacy. IpaB- and IpaD-specific IgA antibody-secreting cells in the lungs and spleen and T-cell-derived IL-2, IL-5, IL-17 and IL-10 were associated with protection. These results demonstrate the immunogenicity of orally administered IpaB and IpaD and support further studies in humans. PMID:23644075

  6. The N-terminus of IpaB provides a potential anchor to the Shigella type III secretion system tip complex protein IpaD

    PubMed Central

    Dickenson, Nicholas E.; Arizmendi, Olivia; Patil, Mrinalini K.; Toth, Ronald T.; Middaugh, C. Russell; Picking, William D.; Picking, Wendy L.

    2014-01-01

    The type III secretion system (T3SS) is an essential virulence factor for Shigella flexneri, providing a conduit through which host-altering effectors are injected directly into a host cell to promote uptake. The type III secretion apparatus (T3SA) is comprised of a basal body, external needle, and regulatory tip complex. The nascent needle is a polymer of MxiH capped by a pentamer of invasion plasmid antigen D (IpaD). Exposure to bile salts (e.g. deoxycholate) causes a conformational change in IpaD and promotes recruitment of IpaB to the needle tip. It has been proposed that IpaB senses contact with host cell membranes, recruiting IpaC and inducing full secretion of T3SS effectors. While the steps of T3SA maturation and their external triggers have been identified, details of specific protein interactions and mechanisms have remained difficult to study due to the hydrophobic nature of the IpaB and IpaC translocator proteins. Here we explored the ability for a series of soluble N-terminal IpaB peptides to interact with IpaD. We found that DOC is required for the interaction and that a region of IpaB between residues 11–27 is required for maximum binding, which was confirmed in vivo. Furthermore, intramolecular FRET measurements indicated that movement of the IpaD distal domain away from the protein core accompanied the binding of IpaB11-226. Together these new findings provide important new insight into the interactions and potential mechanisms that define the maturation of the Shigella T3SA needle tip complex and provide a foundation for further studies probing T3SS activation. PMID:24236510

  7. The IPA--An Opportunity for Intergovernmental Understanding. Resource Paper No. 13.

    ERIC Educational Resources Information Center

    Anderson, Christine E.

    The Intergovernmental Personnel Act Program (IPA), begun in 1971, provides for the temporary exchange of personnel between federal executive agencies and states, local governments, institutions of higher education, and Indian tribal governments to do work of mutual benefit and concern. In the five years following the program's inception, more than…

  8. 46 CFR 502.991 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PROVISIONS RULES OF PRACTICE AND PROCEDURE Paperwork Reduction Act § 502.991 OMB control numbers assigned pursuant to the Paperwork Reduction Act. This section displays the control numbers assigned to information... comply with the Act, which requires that agencies display a current control number assigned by the...

  9. Characterization of a Novel Fusion Protein from IpaB and IpaD of Shigella spp. and Its Potential as a Pan-Shigella Vaccine

    PubMed Central

    Martinez-Becerra, Francisco J.; Chen, Xiaotong; Dickenson, Nicholas E.; Choudhari, Shyamal P.; Harrison, Kelly; Clements, John D.; Picking, William D.; Van De Verg, Lillian L.; Walker, Richard I.

    2013-01-01

    Shigellosis is an important disease in the developing world, where about 90 million people become infected with Shigella spp. each year. We previously demonstrated that the type three secretion apparatus (T3SA) proteins IpaB and IpaD are protective antigens in the mouse lethal pulmonary model. In order to simplify vaccine formulation and process development, we have evaluated a vaccine design that incorporates both of these previously tested Shigella antigens into a single polypeptide chain. To determine if this fusion protein (DB fusion) retains the antigenic and protective capacities of IpaB and IpaD, we immunized mice with the DB fusion and compared the immune response to that elicited by the IpaB/IpaD combination vaccine. Purification of the DB fusion required coexpression with IpgC, the IpaB chaperone, and after purification it maintained the highly α-helical characteristics of IpaB and IpaD. The DB fusion also induced comparable immune responses and retained the ability to protect mice against Shigella flexneri and S. sonnei in the lethal pulmonary challenge. It also offered limited protection against S. dysenteriae challenge. Our results show the feasibility of generating a protective Shigella vaccine comprised of the DB fusion. PMID:24060976

  10. Structural Characterization of the N Terminus of IpaC from Shigella flexneri

    PubMed Central

    Harrington, Amanda T.; Hearn, Patricia D.; Picking, Wendy L.; Barker, Jeffrey R.; Wessel, Andrew; Picking, William D.

    2003-01-01

    The primary effector for Shigella invasion of epithelial cells is IpaC, which is secreted via a type III secretion system. We recently reported that the IpaC N terminus is required for type III secretion and possibly other functions. In this study, mutagenesis was used to identify an N-terminal secretion signal and to determine the functional importance of the rest of the IpaC N terminus. The 15 N-terminal amino acids target IpaC for secretion by Shigella flexneri, and placing additional amino acids at the N terminus does not interfere with IpaC secretion. Furthermore, amino acid sequences with no relationship to the native IpaC secretion signal can also direct its secretion. Deletions introduced beyond amino acid 20 have no effect on secretion and do not adversely affect IpaC function in vivo until they extend beyond residue 50, at which point invasion function is completely eliminated. Deletions introduced at amino acid 100 and extending toward the N terminus reduce IpaC's invasion function but do not eliminate it until they extend to the N-terminal side of residue 80, indicating that a region from amino acid 50 to 80 is critical for IpaC invasion function. To explore this further, the ability of an IpaC N-terminal peptide to associate in vitro with its translocon partner IpaB and its chaperone IpgC was studied. The N-terminal peptide binds tightly to IpaB, but the IpaC central hydrophobic region also appears to participate in this binding. The N-terminal peptide also associates with the chaperone IpgC and IpaB is competitive for this interaction. Based on additional biophysical data, we propose that a region between amino acids 50 and 80 is required for chaperone binding, and that the IpaB binding domain is located downstream from, and possibly overlapping, this region. From these data, we propose that the secretion signal, chaperone binding region, and IpaB binding domain are located at the IpaC N terminus and are essential for presentation of IpaC to host

  11. 7 CFR 1580.602 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Paperwork Reduction Act assigned number. 1580.602 Section 1580.602 Agriculture Regulations of the Department of Agriculture (Continued) FOREIGN AGRICULTURAL SERVICE, DEPARTMENT OF AGRICULTURE TRADE ADJUSTMENT ASSISTANCE FOR FARMERS § 1580.602 Paperwork Reduction...

  12. 7 CFR 1580.602 - Paperwork Reduction Act assigned number.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Paperwork Reduction Act assigned number. 1580.602 Section 1580.602 Agriculture Regulations of the Department of Agriculture (Continued) FOREIGN AGRICULTURAL SERVICE, DEPARTMENT OF AGRICULTURE TRADE ADJUSTMENT ASSISTANCE FOR FARMERS § 1580.602 Paperwork Reduction...

  13. 7 CFR 1425.24 - OMB control number assigned pursuant to Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MARKETING ASSOCIATIONS § 1425.24 OMB control number assigned pursuant to Paperwork Reduction Act. The... Office of Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and have been assigned...

  14. Intradermal delivery of Shigella IpaB and IpaD type III secretion proteins: Kinetics of cell recruitment and antigen uptake, mucosal and systemic immunity, and protection across serotypes

    PubMed Central

    Heine, Shannon J.; Diaz-McNair, Jovita; Andar, Abhay U.; Drachenberg, Cinthia B.; van de Verg, Lillian; Walker, Richard; Picking, Wendy L.; Pasetti, Marcela F.

    2014-01-01

    Shigella is one of the leading pathogens contributing to the vast pediatric diarrheal disease burden in low-income countries. No licensed vaccine is available and the existing candidates are only partially effective and serotype-specific. Shigella type III secretion system proteins IpaB and IpaD, which are conserved across Shigella spp., are candidates for a broadly protective, subunit-based vaccine. Herein, we investigated the immunogenicity and protective efficacy of IpaB and IpaD administered intradermally (i.d.) with a double-mutant of the E. coli heat-labile enterotoxin (dmLT) adjuvant using microneedles. Different dosage levels of IpaB and IpaD with or without dmLT were tested in mice. Vaccine delivery into the dermis, recruitment of neutrophils, macrophages, dendritic cells (DC) and Langerhans cells (LC), and colocalization of vaccine antigens within skin-activated antigen presenting cells (APC) was demonstrated through histology and immunofluorescence microscopy. Ag-loaded neutrophils, macrophages, DC and LC remained in the tissue at least one week. IpaB, IpaD and dmLT-specific serum IgG and IgG secreting cells were produced following i.d. immunization. The protective efficacy was 70% against S. flexneri and 50% against S. sonnei. Similar results were obtained when the vaccine was administered intranasally, with the i.d. route requiring 25-40 times lower doses. Distinctively, IgG was detected in mucosal secretions; sIgA as well as mucosal and systemic IgA antibody secreting cells (ASC) were seemingly absent. Vaccine-induced T cells produced IFN-γ, IL-2, TNF-α, IL-17, IL-4, IL-5 and IL-10. These results demonstrate the potential of i.d. vaccination with IpaB and IpaD to prevent Shigella infection and support further studies in humans. PMID:24453241

  15. 3 CFR - Assignment of Reporting Function Under the American Recovery and Reinvestment Act of 2009

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Assignment of Reporting Function Under the American Recovery and Reinvestment Act of 2009 Presidential Documents Other Presidential Documents Memorandum of May 15, 2009 Assignment of Reporting Function Under the American Recovery and Reinvestment Act of 2009 Memorandum for the Chair of the Council On...

  16. Secretion of Ipa proteins by Shigella flexneri: inducer molecules and kinetics of activation.

    PubMed Central

    Bahrani, F K; Sansonetti, P J; Parsot, C

    1997-01-01

    The type III Mxi-Spa secretion machinery of Shigella flexneri is responsible for secretion of Ipa proteins, which are involved in the entry of bacteria into epithelial cells. Ipa proteins accumulate within bacteria growing in laboratory media, and their secretion is activated upon contact of bacteria with eukaryotic cells. In this study, we have identified a group of chemical compounds, including Congo red, Evans blue, and direct orange, which are able to induce secretion of Ipa proteins by bacteria suspended in phosphate-buffered saline. Parameters of kinetics of activation of Ipa secretion by Congo red were determined by measuring by enzyme-linked immunosorbent assay the amount of IpaC secreted and by investigating the increase in susceptibility of Ipa proteins to proteinase K degradation. Ipa secretion occurred at 37 degrees C, was obtained with 5 to 10 microM Congo red, and was complete within 30 min. In addition, activation of Ipa secretion by Congo red was observed with bacteria harvested throughout the exponential phase of growth but not with bacteria in the stationary phase. The interactions of Congo red and Congo red-related compounds with the Mxi-Spa secretion apparatus might be specific hydrophobic interactions similar to those involved in binding of Congo red to amyloid proteins. PMID:9316999

  17. Slovenia’s Construction Act and Implementation Plans: A Case Study of Izola IPA-8

    NASA Astrophysics Data System (ADS)

    Ažman Momirski, Lucija

    2017-10-01

    The guidelines for urban design in Izola’s IPA-8 planning area, which is earmarked for hotels, apartment complexes, and sports, specify diverse forms of leisure living space required by modern society. The new tourist complex is not a large monotonous hotel complex, but rather a spatial arrangement in which guests experience an authentic local environment and city residents enjoy the new high-quality ambience. The hotel area is defined by three major communication axes from north to south, linking the countryside to the coastal area and opening up attractive sea views in the new complex. Internal east-west links connect buildings and public spaces. Because of the terraced terrain, a large number of paved ramps and internal public gardens have been designed between the structures. The extensions of the communication axes are laid out as squares, named based on the function of the public spaces. Hotel Street is the central axis and main connecting street, with public hotel services and restaurants. The west axis extends into Culture Square, where activities related to Izola’s culture and history are presented; here there is an opportunity to create new galleries, a small local museum, and an exhibition room. Apartment Square is located on the east communication axis, along which only a limited number of trade, catering, and service activities are planned. The plan received first prize in a public competition, and it later developed into detailed municipal spatial plan. In this process, it became clear that Slovenia’s Construction Act (ZGO-1) does not support plans to create terraced buildings.

  18. Preemptive financial strategies help IPAs avoid insolvency.

    PubMed

    Karling, J; Silberman, L

    2000-11-01

    The 1999 collapse in California of practice management giants FPA Medical Management, Inc. and MedPartners, Inc. has caused healthcare provider organizations, particularly independent practice associations (IPAs), to examine critical issues related to financial solvency. Problems such as declining membership, ineffective management, weak contracting, and lack of strategic vision frequently are encountered by troubled provider organizations. The common thread that runs through IPA failures is a combination of unreliable accounting data and inadequate reporting systems. This lack of satisfactory financial and reporting information impairs the ability of the provider group to maintain sufficient funds to cover expenses and pay physicians. Successful, financially stable provider networks use well-defined reporting procedures based on fundamental accounting and financial concepts, as well as a sound methodology for measuring and calculating claims liability estimates. In California, new regulations aimed at encouraging provider organizations to assume preemptive financial strategies are in the process of being adopted. IPAs in every state should consider reviewing these regulations as benchmarks by which to assess their financial procedures.

  19. Recombinant Expression and Purification of the Shigella Translocator IpaB.

    PubMed

    Barta, Michael L; Adam, Philip R; Dickenson, Nicholas E

    2017-01-01

    Type III secretion systems (T3SS) are highly conserved virulence factors employed by a large number of pathogenic gram-negative bacteria. Like many T3SS translocators, recombinant expression of the hydrophobic Shigella protein IpaB requires the presence of its cognate chaperone IpgC. Chaperone-bound IpaB is maintained in a nonfunctional state, which has hampered in vitro studies aimed at understanding molecular structure and function of this important class of T3SS proteins. Herein, we describe an expression and purification protocol that utilizes mild detergents to produce highly purified, homogeneous IpaB of defined oligomeric states.

  20. 46 CFR 147.8 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 147.8 Section 147.8 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) DANGEROUS CARGOES HAZARDOUS SHIPS' STORES General Provisions § 147.8 OMB control numbers assigned pursuant...

  1. 46 CFR 147.8 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 147.8 Section 147.8 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) DANGEROUS CARGOES HAZARDOUS SHIPS' STORES General Provisions § 147.8 OMB control numbers assigned pursuant...

  2. 46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 150.105 Section 150.105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.105 OMB control numbers assigned pursuant to...

  3. 46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 150.105 Section 150.105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.105 OMB control numbers assigned pursuant to...

  4. 46 CFR 147.8 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 147.8 Section 147.8 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) DANGEROUS CARGOES HAZARDOUS SHIPS' STORES General Provisions § 147.8 OMB control numbers assigned pursuant...

  5. 46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 150.105 Section 150.105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.105 OMB control numbers assigned pursuant to...

  6. 46 CFR 147.8 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 147.8 Section 147.8 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) DANGEROUS CARGOES HAZARDOUS SHIPS' STORES General Provisions § 147.8 OMB control numbers assigned pursuant...

  7. 46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 150.105 Section 150.105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.105 OMB control numbers assigned pursuant to...

  8. 46 CFR 150.105 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 150.105 Section 150.105 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES COMPATIBILITY OF CARGOES § 150.105 OMB control numbers assigned pursuant to...

  9. 46 CFR 147.8 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 147.8 Section 147.8 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) DANGEROUS CARGOES HAZARDOUS SHIPS' STORES General Provisions § 147.8 OMB control numbers assigned pursuant...

  10. 46 CFR 565.13 - OMB control number assigned pursuant to the Paperwork Reduction Act

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false OMB control number assigned pursuant to the Paperwork Reduction Act 565.13 Section 565.13 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AND ACTIONS TO ADDRESS RESTRICTIVE FOREIGN MARITIME PRACTICES CONTROLLED CARRIERS § 565.13 OMB control number assigned pursuant to...

  11. 46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 107.05 Section 107.05 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION General § 107.05 OMB control numbers assigned...

  12. 46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 107.05 Section 107.05 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION General § 107.05 OMB control numbers assigned...

  13. 46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 107.05 Section 107.05 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION General § 107.05 OMB control numbers assigned...

  14. 46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 107.05 Section 107.05 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION General § 107.05 OMB control numbers assigned...

  15. 46 CFR 107.05 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 107.05 Section 107.05 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) A-MOBILE OFFSHORE DRILLING UNITS INSPECTION AND CERTIFICATION General § 107.05 OMB control numbers assigned...

  16. 18 CFR 389.101 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... assigned pursuant to the Paperwork Reduction Act. 389.101 Section 389.101 Conservation of Power and Water... FOR COMMISSION INFORMATION COLLECTION REQUIREMENTS § 389.101 OMB control numbers assigned pursuant to... citations affecting § 389.101, see the List of CFR Sections Affected, which appears in the Finding Aids...

  17. 18 CFR 389.101 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... assigned pursuant to the Paperwork Reduction Act. 389.101 Section 389.101 Conservation of Power and Water... FOR COMMISSION INFORMATION COLLECTION REQUIREMENTS § 389.101 OMB control numbers assigned pursuant to... citations affecting § 389.101, see the List of CFR Sections Affected, which appears in the Finding Aids...

  18. Expression of Shigella flexneri ipaB Gene in Tobacco.

    PubMed

    Ohadi, Mandana; Rasouli, Rahimeh; Darzi-Eslam, Elham; Jafari, Anis; Ehsani, Parastoo

    2013-04-01

    Shigellosis is a leading cause of diarrhea in many developing countries and although the disease can be controlled and managed with antibiotics, the constant emergence of resistant species requiring ever newer antibacterial drugs make development of an effective vaccine necessary. The bacteria are highly contagious and since immunity to Shigella is serotype-specific a multi-serotype vaccine is required for adequate protection. Proteins encoded by Shigella invasion plasmid, which are part of the Type Three Secretion System (TTSS) of this bacteria, are good candidate as vaccine targets since they are both immunogenic and conserved between different Shigella species. The advent of molecular farming, which is a low cost system, has opened up new venues for production of recombinant proteins. In view of the difficulties encountered in expressing IpaB in Escherichia coli (E. coli), the feasibility of the expression of this protein in tobacco has been investigated. The ipaB gene was cloned in place of the Hygromycin gene in pCambia1304 containing GFP as a reporter gene. The vector was then transferred into competent Agrobacterium tumefaciens (A. tumefaciens) strain LBA4404 which was used for agro-infiltration of Nicotiana tobaccum (N. tobaccum) leaves. Transformation was confirmed by expression of GFP. The gene was also cloned in pBAD/geneIII A and transformed E. coli host containing the construct was induced using different amounts of L-arabinose as inducer. Expression of IpaB gene by both hosts was determined by Western blotting using anti-IpaB monoclonal antibody. The data obtained showed that IpaB was expressed in plant leaves but expression in E. coli was not detectable. This study showed that N. tobaccum is capable of expressing this protein without its specific chaperon and in levels detectable by Western blotting.

  19. The IPA and the American Psychoanalytic Association: a perspective on the regional association agreement.

    PubMed

    Wallerstein, R S

    1998-06-01

    Ever since 1938 the American Psychoanalytic Association has had a special autonomous relationship within the IPA accorded to no other component organisation. This Regional Association status has had two main features: (1) total internal control over training standards and membership criteria, with no accountability to the IPA; and (2) an 'exclusive franchise', so that the IPA was barred from recognising any other component within the United States. This unique Regional Association status reflected the resolution at the time (1938) of the long-standing controversy between the IPA and the American over the issue of 'lay analysis', and remained unaltered for half a century until, with the resolution of the 3 1/2-year long law-suit against the American (and secondarily against the IPA) in 1988, the Regional Association agreement was modified (but not totally abrogated) by the American's giving up the 'exclusive franchise' aspect (thus permitting IPA recognition of psychoanalytic groups in the US organised outside the American), but still retaining its internal full control over training and membership. The meanings and consequences for psychoanalysis of this special status of the American are explored.

  20. 46 CFR 110.01-2 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 4 2011-10-01 2011-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 110.01-2 Section 110.01-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING GENERAL PROVISIONS Applicability § 110.01-2 OMB control numbers assigned pursuant to...

  1. 46 CFR 110.01-2 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 110.01-2 Section 110.01-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING GENERAL PROVISIONS Applicability § 110.01-2 OMB control numbers assigned pursuant to...

  2. 46 CFR 110.01-2 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 4 2014-10-01 2014-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 110.01-2 Section 110.01-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING GENERAL PROVISIONS Applicability § 110.01-2 OMB control numbers assigned pursuant to...

  3. 46 CFR 188.01-15 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 7 2012-10-01 2012-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 188.01-15 Section 188.01-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS GENERAL PROVISIONS Authority and Purpose § 188.01-15 OMB control numbers assigned...

  4. 46 CFR 188.01-15 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 7 2014-10-01 2014-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 188.01-15 Section 188.01-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS GENERAL PROVISIONS Authority and Purpose § 188.01-15 OMB control numbers assigned...

  5. 46 CFR 188.01-15 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 7 2011-10-01 2011-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 188.01-15 Section 188.01-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS GENERAL PROVISIONS Authority and Purpose § 188.01-15 OMB control numbers assigned...

  6. 46 CFR 188.01-15 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 7 2013-10-01 2013-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 188.01-15 Section 188.01-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS GENERAL PROVISIONS Authority and Purpose § 188.01-15 OMB control numbers assigned...

  7. 46 CFR 188.01-15 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 188.01-15 Section 188.01-15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) OCEANOGRAPHIC RESEARCH VESSELS GENERAL PROVISIONS Authority and Purpose § 188.01-15 OMB control numbers assigned...

  8. 46 CFR 110.01-2 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 110.01-2 Section 110.01-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING GENERAL PROVISIONS Applicability § 110.01-2 OMB control numbers assigned pursuant to...

  9. 46 CFR 110.01-2 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false OMB control numbers assigned pursuant to the Paperwork Reduction Act. 110.01-2 Section 110.01-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING GENERAL PROVISIONS Applicability § 110.01-2 OMB control numbers assigned pursuant to...

  10. Reassessing the plight of physician organizations in California: the uncertain future for IPAs.

    PubMed

    Trauner, J B

    2000-07-01

    With numerous medical groups and individual practice associations (IPAs) in California now reporting operating losses--and many approaching financial insolvency--the question arises why physician organizations are in such a tenuous situation. One line of thinking is that the problem is attributable to the market dominance of the major health plans and their ability to impose actuarially unsound low capitation rates on professional providers. This article describes four other reasons for the current plight of physician organizations: (1) a physician-centric approach to IPA governance, (2) lack of qualified staff within key operating units, (3) management reporting that is insufficient to support utilization analysis and health plan negotiations, and (4) a highly charged political process for determining physician reimbursement. IPA survival will ultimately depend upon whether IPAs are perceived by their physician members and leaders as true business operations or just as another income source.

  11. Detergent Isolation Stabilizes and Activates the Shigella Type III Secretion System Translocator Protein IpaC.

    PubMed

    Bernard, Abram R; Duarte, Shari M; Kumar, Prashant; Dickenson, Nicholas E

    2016-07-01

    Shigella rely on a type III secretion system as the primary virulence factor for invasion and colonization of human hosts. Although there are an estimated 90 million Shigella infections, annually responsible for more than 100,000 deaths worldwide, challenges isolating and stabilizing many type III secretion system proteins have prevented a full understanding of the Shigella invasion mechanism and additionally slowed progress toward a much needed Shigella vaccine. Here, we show that the non-denaturing zwitterionic detergent N, N-dimethyldodecylamine N-oxide (LDAO) and non-ionic detergent n-octyl-oligo-oxyethylene efficiently isolated the hydrophobic Shigella translocator protein IpaC from the co-purified IpaC/IpgC chaperone-bound complex. Both detergents resulted in monomeric IpaC that exhibits strong membrane binding and lysis characteristics while the chaperone-bound complex does not, suggesting that the stabilizing detergents provide a means of following IpaC "activation" in vitro. Additionally, biophysical characterization found that LDAO provides significant thermal and temporal stability to IpaC, protecting it for several days at room temperature and brief exposure to temperatures reaching 90°C. In summary, this work identified and characterized conditions that provide stable, membrane active IpaC, providing insight into key interactions with membranes and laying a strong foundation for future vaccine formulation studies taking advantage of the native immunogenicity of IpaC and the stability provided by LDAO. Copyright © 2016 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  12. 15 CFR 806.18 - OMB control numbers assigned to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false OMB control numbers assigned to the Paperwork Reduction Act. 806.18 Section 806.18 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF ECONOMIC ANALYSIS, DEPARTMENT OF COMMERCE DIRECT INVESTMENT...

  13. 27 CFR 25.5 - OMB control numbers assigned under the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2012-04-01 2012-04-01 false OMB control numbers assigned under the Paperwork Reduction Act. 25.5 Section 25.5 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Scope of Regulations...

  14. 27 CFR 25.5 - OMB control numbers assigned under the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2013-04-01 2013-04-01 false OMB control numbers assigned under the Paperwork Reduction Act. 25.5 Section 25.5 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Scope of Regulations...

  15. 27 CFR 25.5 - OMB control numbers assigned under the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2014-04-01 2014-04-01 false OMB control numbers assigned under the Paperwork Reduction Act. 25.5 Section 25.5 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY ALCOHOL BEER Scope of Regulations...

  16. 27 CFR 25.5 - OMB control numbers assigned under the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false OMB control numbers assigned under the Paperwork Reduction Act. 25.5 Section 25.5 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Scope of Regulations...

  17. 27 CFR 25.5 - OMB control numbers assigned under the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false OMB control numbers assigned under the Paperwork Reduction Act. 25.5 Section 25.5 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS BEER Scope of Regulations...

  18. Oligomeric states of the Shigella translocator protein IpaB provide structural insights into formation of the type III secretion translocon

    PubMed Central

    Dickenson, Nicholas E; Choudhari, Shyamal P; Adam, Philip R; Kramer, Ryan M; Joshi, Sangeeta B; Middaugh, C Russell; Picking, Wendy L; Picking, William D

    2013-01-01

    The Shigella flexneri Type III secretion system (T3SS) senses contact with human intestinal cells and injects effector proteins that promote pathogen entry as the first step in causing life threatening bacillary dysentery (shigellosis). The Shigella Type III secretion apparatus (T3SA) consists of an anchoring basal body, an exposed needle, and a temporally assembled tip complex. Exposure to environmental small molecules recruits IpaB, the first hydrophobic translocator protein, to the maturing tip complex. IpaB then senses contact with a host cell membrane, forming the translocon pore through which effectors are delivered to the host cytoplasm. Within the bacterium, IpaB exists as a heterodimer with its chaperone IpgC; however, IpaB's structural state following secretion is unknown due to difficulties isolating stable protein. We have overcome this by coexpressing the IpaB/IpgC heterodimer and isolating IpaB by incubating the complex in mild detergents. Interestingly, preparation of IpaB with n-octyl-oligo-oxyethylene (OPOE) results in the assembly of discrete oligomers while purification in N,N-dimethyldodecylamine N-oxide (LDAO) maintains IpaB as a monomer. In this study, we demonstrate that IpaB tetramers penetrate phospholipid membranes to allow a size-dependent release of small molecules, suggesting the formation of discrete pores. Monomeric IpaB also interacts with liposomes but fails to disrupt them. From these and additional findings, we propose that IpaB can exist as a tetramer having inherent flexibility, which allows it to cooperatively interact with and insert into host cell membranes. This event may then lay the foundation for formation of the Shigella T3SS translocon pore. PMID:23456854

  19. 7 CFR 51.62 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 FRESH FRUITS, VEGETABLES AND OTHER PRODUCTS 1,2... Management and Budget (OMB) under the provisions of 44 U.S.C. Chapter 35 and have been assigned OMB Control...

  20. NIMROD simulations of the IPA FRC experiment

    NASA Astrophysics Data System (ADS)

    Milroy, Richard

    2015-11-01

    The IPA experiment created a high temperature plasma by merging and compressing supersonic θ-pinch formed FRCs. The NIMROD code has been used to simulate this process. These calculations include the θ-pinch formation and acceleration of two FRC's using the dynamic formation methodology, and their translation to a central compression chamber where they merge and are magnetically compressed. Transport coefficients have been tuned so simulation results agree well with experimental observation. The inclusion of the Hall term is essential for the FRCs merge quickly, as observed experimentally through the excluded flux profiles. The inclusion of a significant anisotropic viscosity is required for the excluded flux profiles to agree well with the experiment. We plan to extend this validation work using the new ARPA-E funded Venti experiment at Helion Energy in Redmond WA. This will be a very well diagnosed experiment where two FRCs merge (like the IPA experiment) and are then compressed to near-fusion conditions. Preliminary calculations with parameters relevant to this experiment have been made, and some numerical issues identified.

  1. Conformational Changes in IpaD from Shigella flexneri Upon Binding Bile Salts Provide Insight into the Second Step of Type III Secretion†

    PubMed Central

    Dickenson, Nicholas E.; Zhang, Lingling; Epler, Chelsea R.; Adam, Philip R.; Picking, Wendy L.; Picking, William D.

    2011-01-01

    Shigella flexneri uses its type III secretion apparatus (TTSA) to inject host-altering proteins into targeted eukaryotic cells. The TTSA is composed of a basal body and an exposed needle with invasion plasmid antigen D (IpaD) forming a tip complex that controls secretion. The bile salt deoxycholate (DOC) stimulates recruitment of the translocator protein IpaB into the maturing TTSA needle tip complex. This process appears to be triggered by a direct interaction between DOC and IpaD. Fluorescence spectroscopy and NMR spectroscopy are used here to confirm the DOC-IpaD interaction and to reveal that IpaD conformational changes upon DOC binding trigger the appearance of IpaB at the needle tip. Förster resonance energy transfer between specific sites on IpaD was used here to identify changes in distances between IpaD domains as a result of DOC binding. To further explore the effects of DOC binding on IpaD structure, NMR chemical shift mapping was employed. The environments of residues within the proposed DOC binding site and additional residues within the “distal” globular domain were perturbed upon DOC binding, further indicating that conformational changes occur within IpaD upon DOC binding. These events are proposed to be responsible for the recruitment of IpaB at the TTSA needle tip. Mutation analyses combined with additional spectroscopic analyses confirms that conformational changes in IpaD induced by DOC binding contribute to the recruitment of IpaB to the S. flexneri TTSA needle tip. These findings lay the foundation for determining how environmental factors promote TTSA needle tip maturation prior to host cell contact. PMID:21126091

  2. An IPA-Embedded Model for Evaluating Creativity Curricula

    ERIC Educational Resources Information Center

    Chang, Chi-Cheng

    2014-01-01

    How to diagnose the effectiveness of creativity-related curricula is a crucial concern in the pursuit of educational excellence. This paper introduces an importance-performance analysis (IPA)-embedded model for curriculum evaluation, using the example of an IT project implementation course to assess the creativity performance deduced from student…

  3. 14 CFR 11.201 - Office of Management and Budget (OMB) control numbers assigned under the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Office of Management and Budget (OMB) control numbers assigned under the Paperwork Reduction Act. 11.201 Section 11.201 Aeronautics and Space... PROCEDURES Paperwork Reduction Act Control Numbers § 11.201 Office of Management and Budget (OMB) control...

  4. Binding Affects the Tertiary and Quaternary Structures of the Shigella Translocator Protein IpaB and its Chaperone IpgC†

    PubMed Central

    Adam, Philip R.; Patil, Mrinalini K.; Dickenson, Nicholas E.; Choudhari, Shyamal; Barta, Michael; Geisbrecht, Brian V.; Picking, Wendy L.; Picking, William D.

    2012-01-01

    Shigella flexneri uses its type III secretion system (T3SS) to promote invasion of human intestinal epithelial cells as the first step in causing shigellosis, a life threatening form of dysentery. The Shigella type III secretion apparatus (T3SA) consists of a basal body that spans the bacterial envelope and an exposed needle that injects effector proteins into target cells. The nascent Shigella T3SA needle is topped with a pentamer of the needle tip protein invasion plasmid antigen D (IpaD). Bile salts trigger recruitment of the first hydrophobic translocator protein, IpaB, to the tip complex where it senses contact with a host membrane. In the bacterial cytoplasm, IpaB exists in a complex with its chaperone IpgC. Several structures of IpgC have been solved and we recently reported the 2.1-Å crystal structure of the N-terminal domain (IpaB74.224) of IpaB. Like IpgC, the IpaB N-terminal domain exists as a homodimer in solution. We now report that when the two are mixed, these homodimers dissociate and form heterodimers having a nanomolar dissociation constant. This is consistent with the equivalent complexes co-purified after being co-expressed in E. coli. Fluorescence data presented here also indicate that the N-terminal domain of IpaB possesses two regions that appear to contribute additively to chaperone binding. It is also likely that the IpaB N terminus adopts an alternative conformation as a result of chaperone binding. The importance of these findings within the functional context of these proteins is discussed. PMID:22497344

  5. Identification of the bile salt binding site on ipad from Shigella flexneri and the influence of ligand binding on IpaD structure

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barta, Michael L.; Guragain, Manita; Adam, Philip

    2012-10-25

    Type III secretion (TTS) is an essential virulence factor for Shigella flexneri, the causative agent of shigellosis. The Shigella TTS apparatus (TTSA) is an elegant nano-machine that is composed of a basal body, an external needle to deliver effectors into human cells, and a needle tip complex that controls secretion activation. IpaD is at the tip of the nascent TTSA needle where it controls the first step of TTS activation. The bile salt deoxycholate (DOC) binds to IpaD to induce recruitment of the translocator protein IpaB into the maturing tip complex. We recently used spectroscopic analyses to show that IpaDmore » undergoes a structural rearrangement that accompanies binding to DOC. Here, we report a crystal structure of IpaD with DOC bound and test the importance of the residues that make up the DOC binding pocket on IpaD function. IpaD binds DOC at the interface between helices {alpha}3 and {alpha}7, with concomitant movement in the orientation of helix {alpha}7 relative to its position in unbound IpaD. When the IpaD residues involved in DOC binding are mutated, some are found to lead to altered invasion and secretion phenotypes. These findings suggest that adoption of a DOC-bound structural state for IpaD primes the Shigella TTSA for contact with host cells. The data presented here and in the studies leading up to this work provide the foundation for developing a model of the first step in Shigella TTS activation.« less

  6. Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages

    PubMed Central

    Suzuki, Shiho; Mimuro, Hitomi; Kim, Minsoo; Ogawa, Michinaga; Ashida, Hiroshi; Toyotome, Takahito; Franchi, Luigi; Suzuki, Masato; Sanada, Takahito; Suzuki, Toshihiko; Tsutsui, Hiroko; Núñez, Gabriel; Sasakawa, Chihiro

    2014-01-01

    When nucleotide-binding oligomerization domain–like receptors (NLRs) sense cytosolic-invading bacteria, they induce the formation of inflammasomes and initiate an innate immune response. In quiescent cells, inflammasome activity is tightly regulated to prevent excess inflammation and cell death. Many bacterial pathogens provoke inflammasome activity and induce inflammatory responses, including cell death, by delivering type III secreted effectors, the rod component flagellin, and toxins. Recent studies indicated that Shigella deploy multiple mechanisms to stimulate NLR inflammasomes through type III secretion during infection. Here, we show that Shigella induces rapid macrophage cell death by delivering the invasion plasmid antigen H7.8 (IpaH7.8) enzyme 3 (E3) ubiquitin ligase effector via the type III secretion system, thereby activating the NLR family pyrin domain-containing 3 (NLRP3) and NLR family CARD domain-containing 4 (NLRC4) inflammasomes and caspase-1 and leading to macrophage cell death in an IpaH7.8 E3 ligase-dependent manner. Mice infected with Shigella possessing IpaH7.8, but not with Shigella possessing an IpaH7.8 E3 ligase-null mutant, exhibited enhanced bacterial multiplication. We defined glomulin/flagellar-associated protein 68 (GLMN) as an IpaH7.8 target involved in IpaH7.8 E3 ligase-dependent inflammasome activation. This protein originally was identified through its association with glomuvenous malformations and more recently was described as a member of a Cullin ring ligase inhibitor. Modifying GLMN levels through overexpression or knockdown led to reduced or augmented inflammasome activation, respectively. Macrophages stimulated with lipopolysaccharide/ATP induced GLMN puncta that localized with the active form of caspase-1. Macrophages from GLMN+/− mice were more responsive to inflammasome activation than those from GLMN+/+ mice. Together, these results highlight a unique bacterial adaptation that hijacks inflammasome activation via

  7. Extraction of glucomannan of porang tuber (Amorphophallus onchophillus) by using IPA

    NASA Astrophysics Data System (ADS)

    Wardhani, Dyah Hesti; Nugroho, Fatoni; Muslihuddin, Mohammad

    2015-12-01

    Amorphophallus oncophyllus also known as porang tuber is a local tuber rich of glucomannan. Due to the unique rheological and the gelling properties, glucomannan is widely employed as emulsifier and stabilizer and has been approved as a food additive by the U.S. Food and Drug Administration (FDA). Isolation method of glucomannan from the tuber affects the mannan properties which in turn influence the scope of the applications. Ethanol solution combined with thermal treatment is commonly applied to purify glucomannan. However, the Amorphophallus sp also contains ˜0.2 mg b-carotenes/100 g dry weight, an impurities which difficult to be removed by ethanol-2 propyl alcohol (IPA) is more effective to remove undesirable components of glucomannan including carotenes compared to ethanol. This research objective was to study the effect of extraction time, temperature, IPA concentration, and ratio of solvent and flour on purification of glucomannan of A. onchophillus. Glucomannan content, starch content and viscosity were determined after the extraction. The highest glucomannan concentration was obtained at extraction by using 80% IPA and ratio of solvent/sample 8:1 (ml/g) for 4 h at 75°C. This condition gave 72.8% glucomannan and 2.69% starch with 4,300 cPs viscosity.

  8. The impact of non-IPA HMOs on the number of hospitals and hospital capacity.

    PubMed

    Chernew, M

    1995-01-01

    Concentration in the hospital market could limit the success of health care reform strategies that rely on managed care to constrain costs. Hospital market capacity also is important because capacity affects both costs and the degree of price competition. Because managed care plans, particularly non-individual practice association (non-IPA) model HMOs, practice a less hospital-intensive style of care, consolidation and downsizing in the hospital market potentially will accompany managed care growth, influencing the long-run effectiveness of managed care cost-containment strategies. Using Standard Metropolitan Statistical Area (SMSA) data from 1982 and 1987, a 10-percentage point increase in non-IPA HMO market share is estimated to reduce the number of hospitals by about 4%, causing an approximate 5% reduction in the number of hospital beds. No statistically significant relationship is found between non-IPA HMO penetration rates and hospital occupancy rates.

  9. 10 CFR 603.675 - Reporting use of IPA for subawards.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Reporting use of IPA for subawards. 603.675 Section 603.675 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Award Terms Affecting Participants' Financial, Property, and Purchasing Systems Financial Matters § 603...

  10. Integrated Power, Avionics, and Software (iPAS) Space Telecommunications Radio System (STRS) Radio User's Guide -- Advanced Exploration Systems (AES)

    NASA Technical Reports Server (NTRS)

    Roche, Rigoberto; Shalkhauser, Mary Jo Windmille

    2017-01-01

    The Integrated Power, Avionics and Software (IPAS) software defined radio (SDR) was implemented on the Reconfigurable, Intelligently-Adaptive Communication System (RAICS) platform, for radio development at NASA Johnson Space Center. Software and hardware description language (HDL) code were delivered by NASA Glenn Research Center for use in the IPAS test bed and for development of their own Space Telecommunications Radio System (STRS) waveforms on the RAICS platform. The purpose of this document is to describe how to setup and operate the IPAS STRS Radio platform with its delivered test waveform.

  11. Influence of Oligomerization State on the Structural Properties of Invasion Plasmid Antigen B (IpaB) from Shigella flexneri in the Presence and Absence of Phospholipid Membranes†

    PubMed Central

    Adam, Philip R.; Dickenson, Nicholas E.; Greenwood, Jamie C.; Picking, Wendy L.; Picking, William D.

    2014-01-01

    Shigella flexneri causes bacillary dysentery, an important cause of mortality among children in the developing world. Shigella secretes effector proteins via its type III secretion system (T3SS) to promote bacterial uptake into human colonic epithelial cells. The T3SS basal body spans the bacterial cell envelope anchoring a surface-exposed needle. A pentamer of invasion plasmid antigen D (IpaD) lies at the nascent needle tip and IpaB is recruited into the needle tip complex upon exposure to bile salts. From here, IpaB forms a translocon pore in the host cell membrane. Although the mechanism by which IpaB inserts into the membrane is unknown, it was recently shown that recombinant IpaB can exist as either a monomer or tetramer. Both of these forms of IpaB associate with membranes, however, only the tetramer forms pores in liposomes. To reveal differences between these membrane-binding events, Cys mutations were introduced throughout IpaB, allowing site-specific fluorescence labeling. Fluorescence quenching was used to determine the influence of oligomerization and/or membrane association on the accessibility of different IpaB regions to small solutes. The data show that the hydrophobic region of tetrameric IpaB is more accessible to solvent relative to the monomer. The hydrophobic region appears to promote membrane interaction for both forms of IpaB, however, more of the hydrophobic region is protected from solvent for the tetramer after membrane association. Limited proteolysis demonstrated that changes in IpaB’s oligomeric state may determine the manner by which it associates with phospholipid membranes and the subsequent outcome of this association. PMID:25103195

  12. The Platelia Aspergillus ELISA in diagnosis of invasive pulmonary aspergilosis (IPA).

    PubMed

    Siemann, M; Koch-Dörfler, M

    2001-01-01

    The sensitivity of a sandwich enzyme-linked immunosorbent assay (ELISA) for detecting Aspergillus galactomannan was evaluated with 66 serum samples and 113 specimens of the respiratory tract obtained from 52 patients with pulmonary diseases. The patients were divided into five groups: proven invasive pulmonary aspergillosis (IPA) (five patients), probable IPA (seven patients), Aspergillus colonization (eight patients) or unlikely Aspergillus infection (27 patients). Another five patients with doubtful diagnostic test results are discussed in detail. The results of the Platelia Aspergillus ELISA (Sanofi Pasteur, Freiburg, Germany) in testing specimens of the respiratory tract were 90% sensitivity in proven (serum 38%), 60% in probable (serum 37%) and 71% in Aspergillus colonization (serum 0%). Furthermore, 85% of the Aspergillus spp. from positive cultures of specimens of the respiratory tract were also detected in the ELISA. A total of 57% of the culture negative specimens of patients with a least one positive culture or proven aspergillosis in a series of specimens were positive in the ELISA.

  13. 15 CFR 30.63 - Office of Management and Budget control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Office of Management and Budget control numbers assigned pursuant to the Paperwork Reduction Act. 30.63 Section 30.63 Commerce and Foreign... FOREIGN TRADE REGULATIONS General Administrative Provisions § 30.63 Office of Management and Budget...

  14. The Integrated Performance Assessment (IPA): Connecting Assessment to Instruction and Learning

    ERIC Educational Resources Information Center

    Adair-Hauck, Bonnie; Glisan, Eileen W.; Koda, Keiko; Swender, Elvira B.; Sandrock, Paul

    2006-01-01

    This article reports on "Beyond the OPI: Integrated Performance Assessment (IPA) Design Project," a three-year (1997-2000) research initiative sponsored by the U.S. Department of Education International Research and Studies Program. The primary goal of the project was to develop an integrated skills assessment prototype that would measure…

  15. Co-administration of rIpaB domain of Shigella with rGroEL of S. Typhi enhances the immune responses and protective efficacy against Shigella infection.

    PubMed

    Chitradevi, Sekar Tamil Selvi; Kaur, Gurpreet; Uppalapati, Sivaramakrishna; Yadav, Anandprakash; Singh, Dependrapratap; Bansal, Anju

    2015-11-01

    Shigella species cause severe bacillary dysentery in humans and are associated with high morbidity and mortality. The Invasion plasmid antigen (IpaB) protein, which is conserved across all Shigella spp., induces macrophage cell death and is required to invade host cells. The present study evaluates the immunogenicity and protective efficacy of the recombinant (r) domain region of IpaB (rIpaB) of S. flexneri. rIpaB was administered either alone or was co-administered with the rGroEL (heat shock protein 60) protein from S. Typhi as an adjuvant in a mouse model of intranasal immunization. The IpaB domain region (37 kDa) of S. flexneri was amplified from an invasion plasmid, cloned, expressed in BL21 Escherichia coli cells and purified. Immunization with the rIpaB domain alone stimulated both humoral and cell-mediated immune responses. Furthermore, robust antibody (IgG, IgA) and T-cell responses were induced when the rIpaB domain was co-administered with rGroEL. Antibody isotyping revealed higher IgG1 and IgG2a antibody titers and increased interferon-gamma (IFN-γ) secretion in the co-administered group. Immunization of mice with the rIpaB domain alone protected 60%-70% of the mice from lethal infection by S. flexneri, S. boydii and S. sonnei, whereas co-administration with rGroEL increased the protective efficacy to 80%-85%. Organ burden and histopathological studies also revealed a significant reduction in lung infection in the co-immunized mice compared with mice immunized with the rIpaB domain alone. This study emphasizes that the co-administration of the rIpaB domain and rGroEL protein improves immune responses in mice and increases protective efficacy against Shigella infection. This is also the first report to evaluate the potential of the GroEL (Hsp 60) protein of S. Typhi as an adjuvant molecule, thereby overcoming the need for commercial adjuvants.

  16. 50 CFR Table 47a to Part 679 - Percent of the AFA Catcher/Processor Sector's Pollock Allocation, Numbers of Chinook Salmon Used...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Annual Threshold Amount, and Percent Used To Calculate IPA Minimum Participation Assigned to Each Catcher... Allocation and Annual Threshold Amount, and Percent Used To Calculate IPA Minimum Participation Assigned to... threshold amount of 13,516 Column H Percent used to calculate IPA minimum participation Vessel name USCG...

  17. Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD.

    PubMed

    Johnson, Steven; Roversi, Pietro; Espina, Marianela; Olive, Andrew; Deane, Janet E; Birket, Susan; Field, Terry; Picking, William D; Blocker, Ariel J; Galyov, Edouard E; Picking, Wendy L; Lea, Susan M

    2007-02-09

    Bacteria expressing type III secretion systems (T3SS) have been responsible for the deaths of millions worldwide, acting as key virulence elements in diseases ranging from plague to typhoid fever. The T3SS is composed of a basal body, which traverses both bacterial membranes, and an external needle through which effector proteins are secreted. We report multiple crystal structures of two proteins that sit at the tip of the needle and are essential for virulence: IpaD from Shigella flexneri and BipD from Burkholderia pseudomallei. The structures reveal that the N-terminal domains of the molecules are intramolecular chaperones that prevent premature oligomerization, as well as sharing structural homology with proteins involved in eukaryotic actin rearrangement. Crystal packing has allowed us to construct a model for the tip complex that is supported by mutations designed using the structure.

  18. Influence of Problem-Based Learning Model of Learning to the Mathematical Communication Ability of Students of Grade XI IPA SMAN 14 Padang

    NASA Astrophysics Data System (ADS)

    Nisa, I. M.

    2018-04-01

    The ability of mathematical communication is one of the goals of learning mathematics expected to be mastered by students. However, reality in the field found that the ability of mathematical communication the students of grade XI IPA SMA Negeri 14 Padang have not developed optimally. This is evident from the low test results of communication skills mathematically done. One of the factors that causes this happens is learning that has not been fully able to facilitate students to develop mathematical communication skills well. By therefore, to improve students' mathematical communication skills required a model in the learning activities. One of the models learning that can be used is Problem Based learning model Learning (PBL). The purpose of this study is to see whether the ability the students' mathematical communication using the PBL model better than the students' mathematical communication skills of the learning using conventional learning in Class XI IPA SMAN 14 Padang. This research type is quasi experiment with design Randomized Group Only Design. Population in this research that is student of class XI IPA SMAN 14 Padang with sample class XI IPA 3 and class XI IPA 4. Data retrieval is done by using communication skill test mathematically shaped essay. To test the hypothesis used U-Mann test Whitney. Based on the results of data analysis, it can be concluded that the ability mathematical communication of students whose learning apply more PBL model better than the students' mathematical communication skills of their learning apply conventional learning in class XI IPA SMA 14 Padang at α = 0.05. This indicates that the PBL learning model effect on students' mathematical communication ability.

  19. Self-Chaperoning of the Type III Secretion System needle tip proteins IpaD and BipD

    PubMed Central

    Johnson, Steven; Roversi, Pietro; Espina, Marianela; Olive, Andrew; Deane, Janet E.; Birket, Susan; Field, Terry; Picking, William D.; Blocker, Ariel; Galyov, Edouard E.; Picking, Wendy L.; Lea, Susan M.

    2007-01-01

    Bacteria expressing type III secretion systems (T3SS) have been responsible for the deaths of millions worldwide, acting as key virulence elements in diseases ranging from plague to typhoid fever. The T3SS is composed of a basal body, which traverses both bacterial membranes, and an external needle through which effector proteins are secreted. We report multiple crystal structures of two proteins that sit at the tip of the needle and are essential for virulence; IpaD from Shigella flexneri and BipD from Burkholderia pseudomallei. The structures reveal that the N-terminal domains of the molecules are intra-molecular chaperones that prevent premature oligomerization, as well as sharing structural homology with proteins involved in eukaryotic actin rearrangement. Crystal packing has allowed us to construct a model for the tip complex that is supported by mutations designed using the structure. PMID:17077085

  20. 28 CFR 100.13 - Directly assignable costs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., COMMUNICATIONS ASSISTANCE FOR LAW ENFORCEMENT ACT OF 1994 § 100.13 Directly assignable costs. (a) A cost is directly assignable to the CALEA compliance effort if it is a plant cost incurred specifically to meet the...

  1. Deoxycholate-Enhanced Shigella Virulence Is Regulated by a Rare π-Helix in the Type Three Secretion System Tip Protein IpaD.

    PubMed

    Bernard, Abram R; Jessop, T Carson; Kumar, Prashant; Dickenson, Nicholas E

    2017-12-12

    Type three secretion systems (T3SS) are specialized nanomachines that support infection by injecting bacterial proteins directly into host cells. The Shigella T3SS has uniquely evolved to sense environmental levels of the bile salt deoxycholate (DOC) and upregulate virulence in response to DOC. In this study, we describe a rare i + 5 hydrogen bonding secondary structure element (π-helix) within the type three secretion system tip protein IpaD that plays a critical role in DOC-enhanced virulence. Specifically, engineered mutations within the π-helix altered the pathogen's response to DOC, with one mutant construct in particular exhibiting an unprecedented reduction in virulence following DOC exposure. Fluorescence polarization binding assays showed that these altered DOC responses are not the result of differences in affinity between IpaD and DOC, but rather differences in the DOC-dependent T3SS tip maturation resulting from binding of IpaD to translocator/effector protein IpaB. Together, these findings begin to uncover the complex mechanism of DOC-enhanced Shigella virulence while identifying an uncommon structural element that may provide a much needed target for non-antibiotic treatment of Shigella infection.

  2. 20 CFR 411.145 - When can my ticket be taken out of assignment?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... assignment? (a) If you assigned your ticket to an EN or a State VR agency acting as an EN, you may take your... ticket out of assignment. The ticket will be no longer assigned to that EN or State VR agency acting as... your ticket is no longer assigned to that EN or State VR agency. You may reassign your ticket under the...

  3. 20 CFR 411.145 - When can my ticket be taken out of assignment?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... assignment? (a) If you assigned your ticket to an EN or a State VR agency acting as an EN, you may take your... ticket out of assignment. The ticket will be no longer assigned to that EN or State VR agency acting as... your ticket is no longer assigned to that EN or State VR agency. You may reassign your ticket under the...

  4. 20 CFR 411.145 - When can my ticket be taken out of assignment?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... assignment? (a) If you assigned your ticket to an EN or a State VR agency acting as an EN, you may take your... ticket out of assignment. The ticket will be no longer assigned to that EN or State VR agency acting as... your ticket is no longer assigned to that EN or State VR agency. You may reassign your ticket under the...

  5. 20 CFR 411.145 - When can my ticket be taken out of assignment?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... assignment? (a) If you assigned your ticket to an EN or a State VR agency acting as an EN, you may take your... ticket out of assignment. The ticket will be no longer assigned to that EN or State VR agency acting as... your ticket is no longer assigned to that EN or State VR agency. You may reassign your ticket under the...

  6. 20 CFR 411.145 - When can my ticket be taken out of assignment?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... assignment? (a) If you assigned your ticket to an EN or a State VR agency acting as an EN, you may take your... ticket out of assignment. The ticket will be no longer assigned to that EN or State VR agency acting as... your ticket is no longer assigned to that EN or State VR agency. You may reassign your ticket under the...

  7. 32 CFR 37.675 - Must I report when I enter into a TIA allowing a for-profit firm to use an IPA?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Must I report when I enter into a TIA allowing a for-profit firm to use an IPA? 37.675 Section 37.675 National Defense Department of Defense OFFICE OF... Must I report when I enter into a TIA allowing a for-profit firm to use an IPA? Yes, you must include...

  8. 20 CFR 61.404 - Assignments; creditors.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Employees' Benefits OFFICE OF WORKERS' COMPENSATION PROGRAMS, DEPARTMENT OF LABOR COMPENSATION FOR INJURY...; creditors. The right of any person to benefits under the Act is not transferable of assignable at law or in... reimbursement for funeral expenses), or rights existing under the Act are subject to execution, levy, attachment...

  9. Impact of Detergent on Biophysical Properties and Immune Response of the IpaDB Fusion Protein, a Candidate Subunit Vaccine against Shigella Species

    PubMed Central

    Chen, Xiaotong; Choudhari, Shyamal P.; Martinez-Becerra, Francisco J.; Kim, Jae Hyun; Dickenson, Nicholas E.; Toth, Ronald T.; Joshi, Sangeeta B.; Greenwood, Jamie C.; Clements, John D.; Picking, William D.; Middaugh, C. Russell

    2014-01-01

    Shigella spp. are causative agents of bacillary dysentery, a human illness with high global morbidity levels, particularly among elderly and infant populations. Shigella infects via the fecal-oral route, and its virulence is dependent upon a type III secretion system (T3SS). Two components of the exposed needle tip complex of the Shigella T3SS, invasion plasmid antigen D (IpaD) and IpaB, have been identified as broadly protective antigens in the mouse lethal pneumonia model. A recombinant fusion protein (DB fusion) was created by joining the coding sequences of IpaD and IpaB. The DB fusion is coexpressed with IpaB's cognate chaperone, IpgC, for proper recombinant expression. The chaperone can then be removed by using the mild detergents octyl oligooxyethelene (OPOE) or N,N-dimethyldodecylamine N-oxide (LDAO). The DB fusion in OPOE or LDAO was used for biophysical characterization and subsequent construction of an empirical phase diagram (EPD). The EPD showed that the DB fusion in OPOE is most stable at neutral pH below 55°C. In contrast, the DB fusion in LDAO exhibited remarkable thermal plasticity, since this detergent prevents the loss of secondary and tertiary structures after thermal unfolding at 90°C, as well as preventing thermally induced aggregation. Moreover, the DB fusion in LDAO induced higher interleukin-17 secretion and provided a higher protective efficacy in a mouse challenge model than did the DB fusion in OPOE. These data indicate that LDAO might introduce plasticity to the protein, promoting thermal resilience and enhanced protective efficacy, which may be important in its use as a subunit vaccine. PMID:25368115

  10. 26 CFR 26.2651-1 - Generation assignment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 14 2011-04-01 2010-04-01 true Generation assignment. 26.2651-1 Section 26.2651... TAXES GENERATION-SKIPPING TRANSFER TAX REGULATIONS UNDER THE TAX REFORM ACT OF 1986 § 26.2651-1 Generation assignment. (a) Special rule for persons with a deceased parent—(1) In general. This paragraph (a...

  11. 26 CFR 26.2651-1 - Generation assignment.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 14 2012-04-01 2012-04-01 false Generation assignment. 26.2651-1 Section 26... GIFT TAXES GENERATION-SKIPPING TRANSFER TAX REGULATIONS UNDER THE TAX REFORM ACT OF 1986 § 26.2651-1 Generation assignment. (a) Special rule for persons with a deceased parent—(1) In general. This paragraph (a...

  12. 26 CFR 26.2651-1 - Generation assignment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 26 Internal Revenue 14 2014-04-01 2013-04-01 true Generation assignment. 26.2651-1 Section 26.2651... TAXES GENERATION-SKIPPING TRANSFER TAX REGULATIONS UNDER THE TAX REFORM ACT OF 1986 § 26.2651-1 Generation assignment. (a) Special rule for persons with a deceased parent—(1) In general. This paragraph (a...

  13. 26 CFR 26.2651-1 - Generation assignment.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 14 2013-04-01 2013-04-01 false Generation assignment. 26.2651-1 Section 26... GIFT TAXES GENERATION-SKIPPING TRANSFER TAX REGULATIONS UNDER THE TAX REFORM ACT OF 1986 § 26.2651-1 Generation assignment. (a) Special rule for persons with a deceased parent—(1) In general. This paragraph (a...

  14. Shigella IpaH Family Effectors as a Versatile Model for Studying Pathogenic Bacteria.

    PubMed

    Ashida, Hiroshi; Sasakawa, Chihiro

    2015-01-01

    Shigella spp. are highly adapted human pathogens that cause bacillary dysentery (shigellosis). Via the type III secretion system (T3SS), Shigella deliver a subset of virulence proteins (effectors) that are responsible for pathogenesis, with functions including pyroptosis, invasion of the epithelial cells, intracellular survival, and evasion of host immune responses. Intriguingly, T3SS effector activity and strategies are not unique to Shigella, but are shared by many other bacterial pathogens, including Salmonella, Yersinia, and enteropathogenic Escherichia coli (EPEC). Therefore, studying Shigella T3SS effectors will not only improve our understanding of bacterial infection systems, but also provide a molecular basis for developing live bacterial vaccines and antibacterial drugs. One of Shigella T3SS effectors, IpaH family proteins, which have E3 ubiquitin ligase activity and are widely conserved among other bacterial pathogens, are very relevant because they promote bacterial survival by triggering cell death and modulating the host immune responses. Here, we describe selected examples of Shigella pathogenesis, with particular emphasis on the roles of IpaH family effectors, which shed new light on bacterial survival strategies and provide clues about how to overcome bacterial infections.

  15. Shigella IpaH Family Effectors as a Versatile Model for Studying Pathogenic Bacteria

    PubMed Central

    Ashida, Hiroshi; Sasakawa, Chihiro

    2016-01-01

    Shigella spp. are highly adapted human pathogens that cause bacillary dysentery (shigellosis). Via the type III secretion system (T3SS), Shigella deliver a subset of virulence proteins (effectors) that are responsible for pathogenesis, with functions including pyroptosis, invasion of the epithelial cells, intracellular survival, and evasion of host immune responses. Intriguingly, T3SS effector activity and strategies are not unique to Shigella, but are shared by many other bacterial pathogens, including Salmonella, Yersinia, and enteropathogenic Escherichia coli (EPEC). Therefore, studying Shigella T3SS effectors will not only improve our understanding of bacterial infection systems, but also provide a molecular basis for developing live bacterial vaccines and antibacterial drugs. One of Shigella T3SS effectors, IpaH family proteins, which have E3 ubiquitin ligase activity and are widely conserved among other bacterial pathogens, are very relevant because they promote bacterial survival by triggering cell death and modulating the host immune responses. Here, we describe selected examples of Shigella pathogenesis, with particular emphasis on the roles of IpaH family effectors, which shed new light on bacterial survival strategies and provide clues about how to overcome bacterial infections. PMID:26779450

  16. Shigella IpaH0722 E3 Ubiquitin Ligase Effector Targets TRAF2 to Inhibit PKC–NF-κB Activity in Invaded Epithelial Cells

    PubMed Central

    Ashida, Hiroshi; Nakano, Hiroyasu; Sasakawa, Chihiro

    2013-01-01

    NF-κB plays a central role in modulating innate immune responses to bacterial infections. Therefore, many bacterial pathogens deploy multiple mechanisms to counteract NF-κB activation. The invasion of and subsequent replication of Shigella within epithelial cells is recognized by various pathogen recognition receptors as pathogen-associated molecular patterns. These receptors trigger innate defense mechanisms via the activation of the NF-κB signaling pathway. Here, we show the inhibition of the NF-κB activation by the delivery of the IpaH E3 ubiquitin ligase family member IpaH0722 using Shigella's type III secretion system. IpaH0722 dampens the acute inflammatory response by preferentially inhibiting the PKC-mediated activation of NF-κB by ubiquitinating TRAF2, a molecule downstream of PKC, and by promoting its proteasome-dependent degradation. PMID:23754945

  17. 50 CFR Table 47b to Part 679 - Percent of the AFA Mothership Sector's Pollock Allocation, Numbers of Chinook Salmon Used To...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Threshold Amount, and Percent Used To Calculate IPA Minimum Participation Assigned to Each Mothership Under... Annual Threshold Amount, and Percent Used To Calculate IPA Minimum Participation Assigned to Each...-out allocation (2,220) Column G Number of Chinook salmon deducted from the annual threshold amount of...

  18. The model of nano-scale copper particle removal from silicon surface in high pressure CO2 + H2O and CO2 + H2O + IPA cleaning solutions.

    PubMed

    Tan, Xin; Chai, Jiajue; Zhang, Xiaogang; Chen, Jiawei

    2011-12-01

    This study focuses on the description of the static forces in CO2-H2O and CO2-H2O-IPA cleaning solutions with a separate fluid phase entrapped between nano-scale copper particles and a silicon surface. Calculations demonstrate that increasing the pressure of the cleaning system decreases net adhesion force (NAF) between the particle and silicon. The NAF of a particle for in CO2-H2O-IPA system is less than that in CO2-H2O system, suggesting that the particles enter into bulk layer more easily as the CO2-H2O cleaning system is added IPA.

  19. Study of the Gray Scale, Polychromatic, Distortion Invariant Neural Networks Using the Ipa Model.

    NASA Astrophysics Data System (ADS)

    Uang, Chii-Maw

    Research in the optical neural network field is primarily motivated by the fact that humans recognize objects better than the conventional digital computers and the massively parallel inherent nature of optics. This research represents a continuous effort during the past several years in the exploitation of using neurocomputing for pattern recognition. Based on the interpattern association (IPA) model and Hamming net model, many new systems and applications are introduced. A gray level discrete associative memory that is based on object decomposition/composition is proposed for recognizing gray-level patterns. This technique extends the processing ability from the binary mode to gray-level mode, and thus the information capacity is increased. Two polychromatic optical neural networks using color liquid crystal television (LCTV) panels for color pattern recognition are introduced. By introducing a color encoding technique in conjunction with the interpattern associative algorithm, a color associative memory was realized. Based on the color decomposition and composition technique, a color exemplar-based Hamming net was built for color image classification. A shift-invariant neural network is presented through use of the translation invariant property of the modulus of the Fourier transformation and the hetero-associative interpattern association (IPA) memory. To extract the main features, a quadrantal sampling method is used to sampled data and then replace the training patterns. Using the concept of hetero-associative memory to recall the distorted object. A shift and rotation invariant neural network using an interpattern hetero-association (IHA) model is presented. To preserve the shift and rotation invariant properties, a set of binarized-encoded circular harmonic expansion (CHE) functions at the Fourier domain is used as the training set. We use the shift and symmetric properties of the modulus of the Fourier spectrum to avoid the problem of centering the CHE

  20. Programmable Logic Device (PLD) Design Description for the Integrated Power, Avionics, and Software (iPAS) Space Telecommunications Radio System (STRS) Radio

    NASA Technical Reports Server (NTRS)

    Shalkhauser, Mary Jo W.

    2017-01-01

    The Space Telecommunications Radio System (STRS) provides a common, consistent framework for software defined radios (SDRs) to abstract the application software from the radio platform hardware. The STRS standard aims to reduce the cost and risk of using complex, configurable and reprogrammable radio systems across NASA missions. To promote the use of the STRS architecture for future NASA advanced exploration missions, NASA Glenn Research Center (GRC) developed an STRS compliant SDR on a radio platform used by the Advance Exploration System program at the Johnson Space Center (JSC) in their Integrated Power, Avionics, and Software (iPAS) laboratory. At the conclusion of the development, the software and hardware description language (HDL) code was delivered to JSC for their use in their iPAS test bed to get hands-on experience with the STRS standard, and for development of their own STRS Waveforms on the now STRS compliant platform.The iPAS STRS Radio was implemented on the Reconfigurable, Intelligently-Adaptive Communication System (RIACS) platform, currently being used for radio development at JSC. The platform consists of a Xilinx ML605 Virtex-6 FPGA board, an Analog Devices FMCOMMS1-EBZ RF transceiver board, and an Embedded PC (Axiomtek eBox 620-110-FL) running the Ubuntu 12.4 operating system. Figure 1 shows the RIACS platform hardware. The result of this development is a very low cost STRS compliant platform that can be used for waveform developments for multiple applications.The purpose of this document is to describe the design of the HDL code for the FPGA portion of the iPAS STRS Radio particularly the design of the FPGA wrapper and the test waveform.

  1. Vacuum aspiration with the IPAS Modified Gynecologic Syringe.

    PubMed

    Balogh, S A

    1983-01-01

    The IPAS Modified Gynecologic Syringe was compared with the electric pump and standard hand pump in a clinical trial of 1227 women undergoing vacuum aspiration. This modified double-valve syringe was designed to fit larger 8 mm, 10 mm and 12 mm cannulae, which are more suitable for late first trimester procedures. The study was conducted at four centers in which the double-valve syringe was used alternately with the vacuum source normally used at each clinic. Although there were notable inter-center differences with respect to certain outcome variables, results were similar for procedures performed at the same center. The only significant finding was the lower proportion of women requiring D & C to complete uterine evacuation among double-valve syringe patients than among hand pump cases at one center. The data indicate that the double-valve syringe is safe and effective for uterine aspiration in women up to 14 weeks' gestation and may be preferable for use in clinics with limited facilities.

  2. Exogenous spatial attention influences figure-ground assignment.

    PubMed

    Vecera, Shaun P; Flevaris, Anastasia V; Filapek, Joseph C

    2004-01-01

    In a hierarchical stage account of vision, figure-ground assignment is thought to be completed before the operation of focal spatial attention. Results of previous studies have supported this account by showing that unpredictive, exogenous spatial precues do not influence figure-ground assignment, although voluntary attention can influence figure-ground assignment. However, in these studies, attention was not summoned directly to a region in a figure-ground display. In three experiments, we addressed the relationship between figure-ground assignment and visuospatial attention. In Experiment 1, we replicated the finding that exogenous precues do not influence figure-ground assignment when they direct attention outside of a figure-ground stimulus. In Experiment 2, we demonstrated that exogenous attention can influence figure-ground assignment if it is directed to one of the regions in a figure-ground stimulus. In Experiment 3, we demonstrated that exogenous attention can influence figure-ground assignment in displays that contain a Gestalt figure-ground cue; this result suggests that figure-ground processes are not entirely completed prior to the operation of focal spatial attention. Exogenous spatial attention acts as a cue for figure-ground assignment and can affect the outcome of figure-ground processes.

  3. 32 CFR 37.660 - What else must I specify concerning audits of for-profit participants by IPAs?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false What else must I specify concerning audits of for-profit participants by IPAs? 37.660 Section 37.660 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS...

  4. 32 CFR 37.660 - What else must I specify concerning audits of for-profit participants by IPAs?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false What else must I specify concerning audits of for-profit participants by IPAs? 37.660 Section 37.660 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS...

  5. 32 CFR 37.660 - What else must I specify concerning audits of for-profit participants by IPAs?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false What else must I specify concerning audits of for-profit participants by IPAs? 37.660 Section 37.660 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS...

  6. A rapid method to identify Salmonella enterica serovar Gallinarum biovar Pullorum using a specific target gene ipaJ.

    PubMed

    Xu, Lijuan; Liu, Zijian; Li, Yang; Yin, Chao; Hu, Yachen; Xie, Xiaolei; Li, Qiuchun; Jiao, Xinan

    2018-06-01

    Salmonella enterica serovar Gallinarum biovar Pullorum (S. Pullorum) is the pathogen of pullorum disease, which leads to severe economic losses in many developing countries. Traditional methods to identify S. enterica have relied on biochemical reactions and serotyping, which are time-consuming with accurate identification if properly carried out. In this study, we developed a rapid polymerase chain reaction (PCR) method targeting the specific gene ipaJ to detect S. Pullorum. Among the 650 S. Pullorum strains isolated from 1962 to 2016 all over China, 644 strains were identified to harbour ipaJ gene in the plasmid pSPI12, accounting for a detection rate of 99.08%. Six strains were ipaJ negative because pSPI12 was not found in these strains according to whole genome sequencing results. There was no cross-reaction with other Salmonella serotypes, including Salmonella enterica serovar Gallinarum biovar Gallinarum (S. Gallinarum), which show a close genetic relationship with S. Pullorum. This shows that the PCR method could distinguish S. Gallinarum from S. Pullorum in one-step PCR without complicated biochemical identification. The limit of detection of this PCR method was as low as 90 fg/μl or 10 2 CFU, which shows a high sensitivity. Moreover, this method was applied to identify Salmonella isolated from the chicken farm and the results were consistent with what we obtained from biochemical reactions and serotyping. Together, all the results demonstrated that this one-step PCR method is simple and feasible to efficiently identify S. Pullorum.

  7. NEPA assignment training PowerPoints and quizzes.

    DOT National Transportation Integrated Search

    2016-10-01

    The objective of these training materials is to provide National Environmental : Policy Act (NEPA) Assignment information to all professionals involved in the NEPA : process. This training is not intended to be a replication of existing NEPA training...

  8. P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate

    PubMed Central

    Wang, Yiming; Gratzke, Christian; Tamalunas, Alexander; Wiemer, Nicolas; Ciotkowska, Anna; Rutz, Beata; Waidelich, Raphaela; Strittmatter, Frank; Liu, Chunxiao; Stief, Christian G.; Hennenberg, Martin

    2016-01-01

    Prostate smooth muscle tone and hyperplastic growth are involved in the pathophysiology and treatment of male lower urinary tract symptoms (LUTS). Available drugs are characterized by limited efficacy. Patients’ adherence is particularly low to combination therapies of 5α-reductase inhibitors and α1-adrenoceptor antagonists, which are supposed to target contraction and growth simultaneously. Consequently, molecular etiology of benign prostatic hyperplasia (BPH) and new compounds interfering with smooth muscle contraction or growth in the prostate are of high interest. Here, we studied effects of p21-activated kinase (PAK) inhibitors (FRAX486, IPA3) in hyperplastic human prostate tissues, and in stromal cells (WPMY-1). In hyperplastic prostate tissues, PAK1, -2, -4, and -6 may be constitutively expressed in catecholaminergic neurons, while PAK1 was detected in smooth muscle and WPMY-1 cells. Neurogenic contractions of prostate strips by electric field stimulation were significantly inhibited by high concentrations of FRAX486 (30 μM) or IPA3 (300 μM), while noradrenaline- and phenylephrine-induced contractions were not affected. FRAX486 (30 μM) inhibited endothelin-1- and -2-induced contractions. In WPMY-1 cells, FRAX486 or IPA3 (24 h) induced concentration-dependent (1–10 μM) degeneration of actin filaments. This was paralleled by attenuation of proliferation rate, being observed from 1 to 10 μM FRAX486 or IPA3. Cytotoxicity of FRAX486 and IPA3 in WPMY-1 cells was time- and concentration-dependent. Stimulation of WPMY-1 cells with endothelin-1 or dihydrotestosterone, but not noradrenaline induced PAK phosphorylation, indicating PAK activation by endothelin-1. Thus, PAK inhibitors may inhibit neurogenic and endothelin-induced smooth muscle contractions in the hyperplastic human prostate, and growth of stromal cells. Targeting prostate smooth muscle contraction and stromal growth at once by a single compound is principally possible, at least under

  9. P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate.

    PubMed

    Wang, Yiming; Gratzke, Christian; Tamalunas, Alexander; Wiemer, Nicolas; Ciotkowska, Anna; Rutz, Beata; Waidelich, Raphaela; Strittmatter, Frank; Liu, Chunxiao; Stief, Christian G; Hennenberg, Martin

    2016-01-01

    Prostate smooth muscle tone and hyperplastic growth are involved in the pathophysiology and treatment of male lower urinary tract symptoms (LUTS). Available drugs are characterized by limited efficacy. Patients' adherence is particularly low to combination therapies of 5α-reductase inhibitors and α1-adrenoceptor antagonists, which are supposed to target contraction and growth simultaneously. Consequently, molecular etiology of benign prostatic hyperplasia (BPH) and new compounds interfering with smooth muscle contraction or growth in the prostate are of high interest. Here, we studied effects of p21-activated kinase (PAK) inhibitors (FRAX486, IPA3) in hyperplastic human prostate tissues, and in stromal cells (WPMY-1). In hyperplastic prostate tissues, PAK1, -2, -4, and -6 may be constitutively expressed in catecholaminergic neurons, while PAK1 was detected in smooth muscle and WPMY-1 cells. Neurogenic contractions of prostate strips by electric field stimulation were significantly inhibited by high concentrations of FRAX486 (30 μM) or IPA3 (300 μM), while noradrenaline- and phenylephrine-induced contractions were not affected. FRAX486 (30 μM) inhibited endothelin-1- and -2-induced contractions. In WPMY-1 cells, FRAX486 or IPA3 (24 h) induced concentration-dependent (1-10 μM) degeneration of actin filaments. This was paralleled by attenuation of proliferation rate, being observed from 1 to 10 μM FRAX486 or IPA3. Cytotoxicity of FRAX486 and IPA3 in WPMY-1 cells was time- and concentration-dependent. Stimulation of WPMY-1 cells with endothelin-1 or dihydrotestosterone, but not noradrenaline induced PAK phosphorylation, indicating PAK activation by endothelin-1. Thus, PAK inhibitors may inhibit neurogenic and endothelin-induced smooth muscle contractions in the hyperplastic human prostate, and growth of stromal cells. Targeting prostate smooth muscle contraction and stromal growth at once by a single compound is principally possible, at least under experimental

  10. The Interactive Effects of Emotion Regulation and Alcohol Intoxication on Lab-Based Intimate Partner Aggression

    PubMed Central

    Watkins, Laura E.; DiLillo, David; Maldonado, Rosalita C.

    2015-01-01

    This study draws on Finkel and Eckhardt’s (2013) I3 framework to examine the interactive effects of two emotion regulation strategies, anger rumination (an impellance factor) and reappraisal (an inhibition factor), and alcohol intoxication (a disinhibition factor), on intimate partner aggression (IPA) perpetration as measured with an analogue aggression task. Participants were 69 couples recruited from a large Midwestern university (total N = 138). Participants’ trait rumination and reappraisal were measured by self-report. Participants were randomized individually to an alcohol or placebo condition, then recalled an anger event while employing one of three randomly assigned emotion regulation conditions (rumination, reappraisal, or uninstructed). Following this, participants completed an analogue aggression task involving ostensibly assigning white noise blasts to their partner. Participants in the alcohol condition displayed greater IPA than participants in the placebo condition for provoked IPA, but not unprovoked IPA. Results also revealed interactions such that for those in the alcohol and rumination group, higher trait reappraisal was related to lower unprovoked IPA. For provoked IPA, higher trait rumination was related to greater IPA among those in the alcohol and rumination condition and those in the placebo and uninstructed condition. In general, results were consistent with I3 theory, suggesting that alcohol disinhibits, rumination impels, and trait reappraisal inhibits IPA. The theoretical and clinical implications of these findings are discussed in the context of current knowledge about the influence of alcohol intoxication and emotion regulation strategies on IPA perpetration. PMID:25844831

  11. The use of importance and performance analysis (IPA) to evaluate effectiveness of the forward auction market agro commodities: A case study

    NASA Astrophysics Data System (ADS)

    Wulansari, Dwi Ratna; Sutopo, Wahyudi; Hisjam, Muh.

    2018-02-01

    The empowering auction market for commodities in East Java Province is one of five auction market revitalization programs conducted by the Republic of Indonesia c.q. Ministry of Trading started in 2014. One of the districts in East Java Province, namely Magetan District utilizes the commodity auction market to improve the competitiveness of their agricultural industry by shortening the supply chain. The Magetan District needs to evaluate their support for farmers or farmer groups to participate in the forward auction market (FAM). Implementation of the FAM commodities is divided into three main processes, namely pre-auction, auction, and post-auction. The auction market is organized to shorten the trading chain. Implementation of the FAM requires good planning, among Seller (namely Farmer or Farmer Group), organizer of Auction (namely Commodity Auction Company), Buyer, and Local Government (namely the farmer facilitator). This article is aimed to develop the instrument of a Performance Measurement Model Using Important and Performance Analysis (IPA) for Improving the FAM Effectiveness of Agro Commodity from Magetan District with Supply Chain Management approach. IPA is implemented at pre-auction, auction, and post-auction. The IPA model results in the diagram to decide the strategies in improving the FAM effectiveness, and then it can encourage farmers to improve welfare and realize the competitiveness of the auctioneer.

  12. 77 FR 6533 - Information Collection Request; Assignment and Joint Payment Elections

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ... Act of 1995, the Commodity Credit Corporation (CCC) and Farm Service Agency (FSA) are seeking comments... assign a cash payment made by FSA or CCC to a third party. In addition, a payment recipient may...). SUPPLEMENTARY INFORMATION: Title: CCC-36, ``Assignment of Payment'', CCC-37, ``Joint Payment Authorization...

  13. Scalable and Cost-Effective Assignment of Mobile Crowdsensing Tasks Based on Profiling Trends and Prediction: The ParticipAct Living Lab Experience

    PubMed Central

    Bellavista, Paolo; Corradi, Antonio; Foschini, Luca; Ianniello, Raffaele

    2015-01-01

    Nowadays, sensor-rich smartphones potentially enable the harvesting of huge amounts of valuable sensing data in urban environments, by opportunistically involving citizens to play the role of mobile virtual sensors to cover Smart City areas of interest. This paper proposes an in-depth study of the challenging technical issues related to the efficient assignment of Mobile Crowd Sensing (MCS) data collection tasks to volunteers in a crowdsensing campaign. In particular, the paper originally describes how to increase the effectiveness of the proposed sensing campaigns through the inclusion of several new facilities, including accurate participant selection algorithms able to profile and predict user mobility patterns, gaming techniques, and timely geo-notification. The reported results show the feasibility of exploiting profiling trends/prediction techniques from volunteers’ behavior; moreover, they quantitatively compare different MCS task assignment strategies based on large-scale and real MCS data campaigns run in the ParticipAct living lab, an ongoing MCS real-world experiment that involved more than 170 students of the University of Bologna for more than one year. PMID:26263985

  14. 75 FR 7266 - Roaring Fork Valley Physicians I.P.A.; Analysis of the Agreement Containing Consent Order to Aid...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-18

    ... FEDERAL TRADE COMMISSION [File No. 061 0172] Roaring Fork Valley Physicians I.P.A.; Analysis of... attached Analysis to Aid Public Comment describes both the allegations in the draft complaint and the terms... Commission, has been placed on the public record for a period of thirty (30) days. The following Analysis to...

  15. 20 CFR 422.607 - Limited reopening of assignments.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Limited reopening of assignments. 422.607 Section 422.607 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES Administrative Review Process Under the Coal Industry Retiree Health Benefit Act of 1992 § 422.607 Limited...

  16. 20 CFR 422.607 - Limited reopening of assignments.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Limited reopening of assignments. 422.607 Section 422.607 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES Administrative Review Process Under the Coal Industry Retiree Health Benefit Act of 1992 § 422.607 Limited...

  17. 20 CFR 422.607 - Limited reopening of assignments.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Limited reopening of assignments. 422.607 Section 422.607 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES Administrative Review Process Under the Coal Industry Retiree Health Benefit Act of 1992 § 422.607 Limited...

  18. 20 CFR 422.607 - Limited reopening of assignments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Limited reopening of assignments. 422.607 Section 422.607 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES Administrative Review Process Under the Coal Industry Retiree Health Benefit Act of 1992 § 422.607 Limited...

  19. Classes of Discourse, Acts of Discourse, Writers, and Readers.

    ERIC Educational Resources Information Center

    Larson, Richard L.

    1992-01-01

    Argues that a prevalent mistake made by teachers preparing writing curricula and assignments is dividing writing into classes or modes. Suggests alternatives to classifying writing. Envisions writing as a discourse act and assignments as performance of such acts. (HB)

  20. 20 CFR 411.140 - When may I assign my ticket and how?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...). You may assign your ticket during the 90-day period after your case is closed by a State VR agency that elected the VR cost reimbursement option (see § 411.171(d)), without meeting the requirements of... to provide you with services, or you may assign your ticket to a State VR agency acting as an EN if...

  1. 20 CFR 411.140 - When may I assign my ticket and how?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...). You may assign your ticket during the 90-day period after your case is closed by a State VR agency that elected the VR cost reimbursement option (see § 411.171(d)), without meeting the requirements of... to provide you with services, or you may assign your ticket to a State VR agency acting as an EN if...

  2. 20 CFR 411.140 - When may I assign my ticket and how?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...). You may assign your ticket during the 90-day period after your case is closed by a State VR agency that elected the VR cost reimbursement option (see § 411.171(d)), without meeting the requirements of... to provide you with services, or you may assign your ticket to a State VR agency acting as an EN if...

  3. 20 CFR 411.140 - When may I assign my ticket and how?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...). You may assign your ticket during the 90-day period after your case is closed by a State VR agency that elected the VR cost reimbursement option (see § 411.171(d)), without meeting the requirements of... to provide you with services, or you may assign your ticket to a State VR agency acting as an EN if...

  4. 20 CFR 411.140 - When may I assign my ticket and how?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...). You may assign your ticket during the 90-day period after your case is closed by a State VR agency that elected the VR cost reimbursement option (see § 411.171(d)), without meeting the requirements of... to provide you with services, or you may assign your ticket to a State VR agency acting as an EN if...

  5. 42 CFR 433.146 - Rights assigned; assignment method.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Rights assigned; assignment method. 433.146 Section 433.146 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Assignment of Rights to Benefits § 433.146 Rights assigned; assignment method. (a) Except as specified in...

  6. 42 CFR 433.146 - Rights assigned; assignment method.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Rights assigned; assignment method. 433.146 Section 433.146 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Assignment of Rights to Benefits § 433.146 Rights assigned; assignment method. (a) Except as specified in...

  7. 42 CFR 433.146 - Rights assigned; assignment method.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Rights assigned; assignment method. 433.146 Section 433.146 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Assignment of Rights to Benefits § 433.146 Rights assigned; assignment method. (a) Except as specified in...

  8. Position statement. The right to accept or reject an assignment. American Nurses Association.

    PubMed

    1996-01-01

    The American Nurses Association (ANA) believes that nurses should reject assignment that puts patients or themselves in serious, immediate jeopardy. ANA supports the nurses obligation to reject an assignment in these situations even where there is not a specific legal protection for rejecting such an assignment. The professional obligations to the nurse to safeguard clients are grounded in the ethical norms of the profession, the Standards of Clinical Nursing Practice and state nurse practice acts.

  9. Lower region: a new cue for figure-ground assignment.

    PubMed

    Vecera, Shaun P; Vogel, Edward K; Woodman, Geoffrey F

    2002-06-01

    Figure-ground assignment is an important visual process; humans recognize, attend to, and act on figures, not backgrounds. There are many visual cues for figure-ground assignment. A new cue to figure-ground assignment, called lower region, is presented: Regions in the lower portion of a stimulus array appear more figurelike than regions in the upper portion of the display. This phenomenon was explored, and it was demonstrated that the lower-region preference is not influenced by contrast, eye movements, or voluntary spatial attention. It was found that the lower region is defined relative to the stimulus display, linking the lower-region preference to pictorial depth perception cues. The results are discussed in terms of the environmental regularities that this new figure-ground cue may reflect.

  10. iPAS: AES Flight System Technology Maturation for Human Spaceflight

    NASA Technical Reports Server (NTRS)

    Othon, William L.

    2014-01-01

    In order to realize the vision of expanding human presence in space, NASA will develop new technologies that can enable future crewed spacecraft to go far beyond Earth orbit. These technologies must be matured to the point that future project managers can accept the risk of incorporating them safely and effectively within integrated spacecraft systems, to satisfy very challenging mission requirements. The technologies must also be applied and managed within an operational context that includes both on-board crew and mission support on Earth. The Advanced Exploration Systems (AES) Program is one part of the NASA strategy to identify and develop key capabilities for human spaceflight, and mature them for future use. To support this initiative, the Integrated Power Avionics and Software (iPAS) environment has been developed that allows engineers, crew, and flight operators to mature promising technologies into applicable capabilities, and to assess the value of these capabilities within a space mission context. This paper describes the development of the integration environment to support technology maturation and risk reduction, and offers examples of technology and mission demonstrations executed to date.

  11. Negotiating Assignment Pathways: Students and Academic Assignments

    ERIC Educational Resources Information Center

    McDowell, Liz

    2008-01-01

    Existing research identifies that students' approaches to assignments are related to their general approaches to study. It is suggested that students need to better understand the requirements of assignments and acquire new concepts such as "argument". This fine-grained study proposes four qualitatively distinct assignment pathways: gathering,…

  12. 76 FR 43729 - Notice of Random Assignment Study To Evaluate Workforce Investment Act Adult and Dislocated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-21

    ... DEPARTMENT OF LABOR Employment and Training Administration Notice of Random Assignment Study To... interest to use a random assignment impact methodology for the study. In the local workforce investment... study during a 12-18 month period. The Department is soliciting comments concerning the Department's...

  13. Use of IPA to demonstrate loss of forest interior birds from isolated woodlots

    USGS Publications Warehouse

    Robbins, C.S.; Boone, D.D.; Purroy, F.J.

    1983-01-01

    'Empleo de indices puntuales de abundancia (IPA) para demostrar la perdida de aves forestales en bosques aislados'. En Maryland, E.U., se seleccionaron bloques boscosos de diferente superficie, divididos en seis clase de tamano (2,8-6 ha, 7-14, 20-30, 34-80, 105-1300, mayores de 4000 ha). En estas ?islas' forestales fue programado un conjunto de muestreos puntuales con estas caracteristicas: 1) Cada punto se visito tres veces. 2) En cada visita se hicieron cuatro censos consecutivos de 5 minutos de duracion, empleando diferentes simbolos para machos cantores, adultos no cantores, aves en vuelo y aves inmaduras. 3) Los conteos se hicieron en tres epocas: final de Mayo, mitad de Junio y final de Junio. 4) Se dividio el tiempo de censo en tres priodos horarios: 5,15-6,30 ; 6,30-8; 8-9,30 hrs. 5) Los puntos se agruparon en co juntos de 4 a 9, considerando que un conjunto es el nlimero que un observador puede cubrir por manana. 6) La vegetacion fue descrita exhaustivamente en cuanto composicion y fisionomla. El principal objetivo que se busca consiste en conocer los requisitos areales de ciertas especies de bosque muy sensibles a la fragmentacion del habitat. Puede observarse (Figura 1) que una serie de migrantes de largo alcance se asientan en relacion con el aumento de la superficie del rodal arbo1ado, sabre todo en macizos de 4.000 o mas hectareas. Sin embargo, las especies sedentarias (Fig. 2) tienen pauta de presencia irregular en funcion del area, forestal, con tendencia a presentarse menos en los bosques mas extensos, Dryocopus pileatus, por excepcion, reacciona negativamente al pequeno tamano de la parcela arbolado, prefiriendo bosques grandes. Parecida respuesta da tambien Sitta carolinensis. Aunque se sabe poco de las exigencias areales de las aves forestales americanas, el metodo de los IPA resulta muy adecuado para esta clase de investigacion de tanto interes en gestion ambiental, posibilitando colectar gran cantidad de datos comparables en un periodo de

  14. Waveform Developer's Guide for the Integrated Power, Avionics, and Software (iPAS) Space Telecommunications Radio System (STRS) Radio

    NASA Technical Reports Server (NTRS)

    Shalkhauser, Mary Jo W.; Roche, Rigoberto

    2017-01-01

    The Space Telecommunications Radio System (STRS) provides a common, consistent framework for software defined radios (SDRs) to abstract the application software from the radio platform hardware. The STRS standard aims to reduce the cost and risk of using complex, configurable and reprogrammable radio systems across NASA missions. To promote the use of the STRS architecture for future NASA advanced exploration missions, NASA Glenn Research Center (GRC) developed an STRS-compliant SDR on a radio platform used by the Advance Exploration System program at the Johnson Space Center (JSC) in their Integrated Power, Avionics, and Software (iPAS) laboratory. The iPAS STRS Radio was implemented on the Reconfigurable, Intelligently-Adaptive Communication System (RIACS) platform, currently being used for radio development at JSC. The platform consists of a Xilinx(Trademark) ML605 Virtex(Trademark)-6 FPGA board, an Analog Devices FMCOMMS1-EBZ RF transceiver board, and an Embedded PC (Axiomtek(Trademark) eBox 620-110-FL) running the Ubuntu 12.4 operating system. The result of this development is a very low cost STRS compliant platform that can be used for waveform developments for multiple applications. The purpose of this document is to describe how to develop a new waveform using the RIACS platform and the Very High Speed Integrated Circuits (VHSIC) Hardware Description Language (VHDL) FPGA wrapper code and the STRS implementation on the Axiomtek processor.

  15. Hardware Interface Description for the Integrated Power, Avionics, and Software (iPAS) Space Telecommunications Radio Ssystem (STRS) Radio

    NASA Technical Reports Server (NTRS)

    Shalkhauser, Mary Jo W.; Roche, Rigoberto

    2017-01-01

    The Space Telecommunications Radio System (STRS) provides a common, consistent framework for software defined radios (SDRs) to abstract the application software from the radio platform hardware. The STRS standard aims to reduce the cost and risk of using complex, configurable and reprogrammable radio systems across NASA missions. To promote the use of the STRS architecture for future NASA advanced exploration missions, NASA Glenn Research Center (GRC) developed an STRS-compliant SDR on a radio platform used by the Advance Exploration System program at the Johnson Space Center (JSC) in their Integrated Power, Avionics, and Software (iPAS) laboratory. The iPAS STRS Radio was implemented on the Reconfigurable, Intelligently-Adaptive Communication System (RIACS) platform, currently being used for radio development at JSC. The platform consists of a Xilinx ML605 Virtex-6 FPGA board, an Analog Devices FMCOMMS1-EBZ RF transceiver board, and an Embedded PC (Axiomtek eBox 620-110-FL) running the Ubuntu 12.4 operating system. Figure 1 shows the RIACS platform hardware. The result of this development is a very low cost STRS compliant platform that can be used for waveform developments for multiple applications.The purpose of this document is to describe how to develop a new waveform using the RIACS platform and the Very High Speed Integrated Circuits (VHSIC) Hardware Description Language (VHDL) FPGA wrapper code and the STRS implementation on the Axiomtek processor.

  16. 32 CFR 37.675 - Must I report when I enter into a TIA allowing a for-profit firm to use an IPA?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Must I report when I enter into a TIA allowing a for-profit firm to use an IPA? 37.675 Section 37.675 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE DoD GRANT AND AGREEMENT REGULATIONS TECHNOLOGY INVESTMENT AGREEMENTS Award...

  17. The meanings of suicidal behaviour to psychology students in Ghana: a qualitative approach.

    PubMed

    Osafo, Joseph; Hjelmeland, Heidi; Akotia, Charity S; Knizek, Birthe Loa

    2011-11-01

    The objective of this study was to examine psychology students' attitudes toward suicidal behaviour and the meanings they assign to the act. In-depth interviews were conducted with 15 final year psychology students at a university in Ghana. Interpretative Phenomenological Analysis (IPA) was used to analyze the data. The results indicated that the students had a generalized negative attitude toward suicide. Religious beliefs and family harmony are cultural contexts influencing the interpretation of suicidal behaviour as breach of divine and communal moralities. The implications of these meanings of suicidal behaviour for suicide prevention in Ghana are discussed.

  18. 20 CFR 670.460 - What restrictions are there on the assignment of eligible applicants for nonresidential...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What restrictions are there on the assignment of eligible applicants for nonresidential enrollment in Job Corps? 670.460 Section 670.460 Employees... WORKFORCE INVESTMENT ACT Recruitment, Eligibility, Screening, Selection and Assignment, and Enrollment § 670...

  19. Antigen-specific B memory cell responses to lipopolysaccharide (LPS) and invasion plasmid antigen (Ipa) B elicited in volunteers vaccinated with live-attenuated Shigella flexneri 2a vaccine candidates

    PubMed Central

    Simon, J.K.; Wahid, R.; Maciel, M.; Picking, W.L.; Kotloff, K.L.; Levine, M.M.; Sztein, M.B.

    2013-01-01

    We evaluated B memory responses in healthy adult volunteers who received one oral dose of live-attenuated Shigella flexneri 2a vaccine. LPS-specific BM cells increased from a median of 0 at baseline to 20 spot forming cells (SFC)/106 expanded cells following vaccination (p = 0.008). A strong correlation was found between post-vaccination anti-LPS BM cell counts and peak serum anti-LPS IgG titers (rs = 0.95, p = 0.0003). Increases in BM specific for IpaB approaching significance were also observed. In sum, oral vaccination with live-attenuated S. flexneri 2a elicits BM cells to LPS and IpaB, suggesting that BM responses to Shigella antigens should be further studied as a suitable surrogate of protection in shigellosis. PMID:19022324

  20. Service quality benchmarking via a novel approach based on fuzzy ELECTRE III and IPA: an empirical case involving the Italian public healthcare context.

    PubMed

    La Fata, Concetta Manuela; Lupo, Toni; Piazza, Tommaso

    2017-11-21

    A novel fuzzy-based approach which combines ELECTRE III along with the Importance-Performance Analysis (IPA) is proposed in the present work to comparatively evaluate the service quality in the public healthcare context. Specifically, ELECTRE III is firstly considered to compare the service performance of examined hospitals in a noncompensatory manner. Afterwards, IPA is employed to support the service quality management to point out improvement needs and their priorities. The proposed approach also incorporates features of the Fuzzy Set Theory so as to address the possible uncertainty, subjectivity and vagueness of involved experts in evaluating the service quality. The model is applied to five major Sicilian public hospitals, and strengths and criticalities of the delivered service are finally highlighted and discussed. Although several approaches combining multi-criteria methods have already been proposed in the literature to evaluate the service performance in the healthcare field, to the best of the authors' knowledge the present work represents the first attempt at comparing service performance of alternatives in a noncompensatory manner in the investigated context.

  1. Writing Assignments with a Metacognitive Component Enhance Learning in a Large Introductory Biology Course

    PubMed Central

    Mynlieff, Michelle; Manogaran, Anita L.; St. Maurice, Martin

    2014-01-01

    Writing assignments, including note taking and written recall, should enhance retention of knowledge, whereas analytical writing tasks with metacognitive aspects should enhance higher-order thinking. In this study, we assessed how certain writing-intensive “interventions,” such as written exam corrections and peer-reviewed writing assignments using Calibrated Peer Review and including a metacognitive component, improve student learning. We designed and tested the possible benefits of these approaches using control and experimental variables across and between our three-section introductory biology course. Based on assessment, students who corrected exam questions showed significant improvement on postexam assessment compared with their nonparticipating peers. Differences were also observed between students participating in written and discussion-based exercises. Students with low ACT scores benefited equally from written and discussion-based exam corrections, whereas students with midrange to high ACT scores benefited more from written than discussion-based exam corrections. Students scored higher on topics learned via peer-reviewed writing assignments relative to learning in an active classroom discussion or traditional lecture. However, students with low ACT scores (17–23) did not show the same benefit from peer-reviewed written essays as the other students. These changes offer significant student learning benefits with minimal additional effort by the instructors. PMID:26086661

  2. Antigen-specific B memory cell responses to lipopolysaccharide (LPS) and invasion plasmid antigen (Ipa) B elicited in volunteers vaccinated with live-attenuated Shigella flexneri 2a vaccine candidates.

    PubMed

    Simon, J K; Wahid, R; Maciel, M; Picking, W L; Kotloff, K L; Levine, M M; Sztein, M B

    2009-01-22

    We evaluated B memory responses in healthy adult volunteers who received one oral dose of live-attenuated Shigella flexneri 2a vaccine. LPS-specific B(M) cells increased from a median of 0 at baseline to 20 spot forming cells (SFC)/10(6) expanded cells following vaccination (p=0.008). A strong correlation was found between post-vaccination anti-LPS B(M) cell counts and peak serum anti-LPS IgG titers (rs=0.95, p=0.0003). Increases in B(M) specific for IpaB approaching significance were also observed. In sum, oral vaccination with live-attenuated S. flexneri 2a elicits B(M) cells to LPS and IpaB, suggesting that B(M) responses to Shigella antigens should be further studied as a suitable surrogate of protection in shigellosis.

  3. 32 CFR 505.3 - Privacy Act systems of records.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 3 2014-07-01 2014-07-01 false Privacy Act systems of records. 505.3 Section... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.3 Privacy Act systems of records. (a) Systems... assigned to an individual. (2) Privacy Act systems of records must be— (i) Authorized by Federal statute or...

  4. 32 CFR 505.3 - Privacy Act systems of records.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 3 2013-07-01 2013-07-01 false Privacy Act systems of records. 505.3 Section... AUTHORITIES AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.3 Privacy Act systems of records. (a) Systems... assigned to an individual. (2) Privacy Act systems of records must be— (i) Authorized by Federal statute or...

  5. Assignment Choice, Effort, and Assignment Completion: Does Work Ethic Predict Those Who Choose Higher-Effort Assignments?

    ERIC Educational Resources Information Center

    Parkhurst, John T.; Fleisher, Matthew S.; Skinner, Christopher H.; Woehr, David J.; Hawthorn-Embree, Meredith L.

    2011-01-01

    After completing the Multidimensional Work-Ethic Profile (MWEP), 98 college students were given a 20-problem math computation assignment and instructed to stop working on the assignment after completing 10 problems. Next, they were allowed to choose to finish either the partially completed assignment that had 10 problems remaining or a new…

  6. Expression, limited proteolysis and preliminary crystallographic analysis of IpaD, a component of the Shigella flexneri type III secretion system

    PubMed Central

    Johnson, Steven; Roversi, Pietro; Espina, Marianela; Deane, Janet E.; Birket, Susan; Picking, William D.; Blocker, Ariel; Picking, Wendy L.; Lea, Susan M.

    2006-01-01

    IpaD, the putative needle-tip protein of the Shigella flexneri type III secretion system, has been overexpressed and purified. Crystals were grown of the native protein in space group P212121, with unit-cell parameters a = 55.9, b = 100.7, c = 112.0 Å, and data were collected to 2.9 Å resolution. Analysis of the native Patterson map revealed a peak at 50% of the origin on the Harker section v = 0.5, suggesting twofold non-crystallographic symmetry parallel to the b crystallographic axis. As attempts to derivatize or grow selenomethionine-labelled protein crystals failed, in-drop proteolysis was used to produce new crystal forms. A trace amount of subtilisin Carlsberg was added to IpaD before sparse-matrix screening, resulting in the production of several new crystal forms. This approach produced SeMet-labelled crystals and diffraction data were collected to 3.2 Å resolution. The SeMet crystals belong to space group C2, with unit-cell parameters a = 139.4, b = 45.0, c = 99.5 Å, β = 107.9°. An anomalous difference Patterson map revealed peaks on the Harker section v = 0, while the self-rotation function indicates the presence of a twofold noncrystallographic symmetry axis, which is consistent with two molecules per asymmetric unit. PMID:16946465

  7. Expression, limited proteolysis and preliminary crystallographic analysis of IpaD, a component of the Shigella flexneri type III secretion system.

    PubMed

    Johnson, Steven; Roversi, Pietro; Espina, Marianela; Deane, Janet E; Birket, Susan; Picking, William D; Blocker, Ariel; Picking, Wendy L; Lea, Susan M

    2006-09-01

    IpaD, the putative needle-tip protein of the Shigella flexneri type III secretion system, has been overexpressed and purified. Crystals were grown of the native protein in space group P2(1)2(1)2(1), with unit-cell parameters a = 55.9, b = 100.7, c = 112.0 A, and data were collected to 2.9 A resolution. Analysis of the native Patterson map revealed a peak at 50% of the origin on the Harker section v = 0.5, suggesting twofold non-crystallographic symmetry parallel to the b crystallographic axis. As attempts to derivatize or grow selenomethionine-labelled protein crystals failed, in-drop proteolysis was used to produce new crystal forms. A trace amount of subtilisin Carlsberg was added to IpaD before sparse-matrix screening, resulting in the production of several new crystal forms. This approach produced SeMet-labelled crystals and diffraction data were collected to 3.2 A resolution. The SeMet crystals belong to space group C2, with unit-cell parameters a = 139.4, b = 45.0, c = 99.5 A, beta = 107.9 degrees . An anomalous difference Patterson map revealed peaks on the Harker section v = 0, while the self-rotation function indicates the presence of a twofold noncrystallographic symmetry axis, which is consistent with two molecules per asymmetric unit.

  8. 32 CFR 505.3 - Privacy Act systems of records.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 3 2011-07-01 2009-07-01 true Privacy Act systems of records. 505.3 Section 505... AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.3 Privacy Act systems of records. (a) Systems of... assigned to an individual. (2) Privacy Act systems of records must be— (i) Authorized by Federal statute or...

  9. 32 CFR 505.3 - Privacy Act systems of records.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 3 2012-07-01 2009-07-01 true Privacy Act systems of records. 505.3 Section 505... AND PUBLIC RELATIONS ARMY PRIVACY ACT PROGRAM § 505.3 Privacy Act systems of records. (a) Systems of... assigned to an individual. (2) Privacy Act systems of records must be— (i) Authorized by Federal statute or...

  10. 7 CFR 62.400 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) LIVESTOCK, MEAT, AND OTHER AGRICULTURAL COMMODITIES (QUALITY SYSTEMS VERIFICATION...

  11. 7 CFR 900.601 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS Information Collection § 900.601 OMB control numbers assigned pursuant to the... information collection requirements by the Office of Management and Budget contained in 7 CFR parts 905...

  12. 32 CFR Appendix C to Part 37 - What Is the Desired Coverage for Periodic Audits of For-Profit Participants To Be Audited by IPAs?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false What Is the Desired Coverage for Periodic Audits of For-Profit Participants To Be Audited by IPAs? C Appendix C to Part 37 National Defense Department... INVESTMENT AGREEMENTS Pt. 37, App. C Appendix C to Part 37—What Is the Desired Coverage for Periodic Audits...

  13. Co-Teachers and Parents' Perceptions of Shortened Assignments for Learning Disabled Students

    ERIC Educational Resources Information Center

    Gutierrez, Yxstian

    2013-01-01

    The Individual with Disabilities in Education Act (IDEA) 2007, a federal special education law, states that students with disabilities requiring special education services can use accommodations or adaptations of the curriculum to access the general education curriculum. A shortened assignment, as an accommodation, can help learning disabled…

  14. 7 CFR 1000.93 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Milk), DEPARTMENT OF AGRICULTURE GENERAL PROVISIONS OF FEDERAL MILK MARKETING ORDERS Miscellaneous Provisions § 1000.93 OMB control number assigned... have been approved by the Office of Management and Budget (OMB) under the provisions of Title 44 U.S.C...

  15. BTEC Integrative Assignments.

    ERIC Educational Resources Information Center

    Foot, G. E.

    1992-01-01

    To equip electrical engineering students with common and transferable work skills, a program of integrative assignments was created to develop communication and teamwork skills. Discusses assignment components; the log book, a personal account of each assignment; assessment; conversion of "common skills" to competence statements, and…

  16. Prefrontal Neurons Encode a Solution to the Credit-Assignment Problem

    PubMed Central

    Perge, János A.; Eskandar, Emad N.

    2017-01-01

    To adapt successfully to our environments, we must use the outcomes of our choices to guide future behavior. Critically, we must be able to correctly assign credit for any particular outcome to the causal features which preceded it. In some cases, the causal features may be immediately evident, whereas in others they may be separated in time or intermingled with irrelevant environmental stimuli, creating a potentially nontrivial credit-assignment problem. We examined the neuronal representation of information relevant for credit assignment in the dorsolateral prefrontal cortex (dlPFC) of two male rhesus macaques performing a task that elicited key aspects of this problem. We found that neurons conveyed the information necessary for credit assignment. Specifically, neuronal activity reflected both the relevant cues and outcomes at the time of feedback and did so in a manner that was stable over time, in contrast to prior reports of representational instability in the dlPFC. Furthermore, these representations were most stable early in learning, when credit assignment was most needed. When the same features were not needed for credit assignment, these neuronal representations were much weaker or absent. These results demonstrate that the activity of dlPFC neurons conforms to the basic requirements of a system that performs credit assignment, and that spiking activity can serve as a stable mechanism that links causes and effects. SIGNIFICANCE STATEMENT Credit assignment is the process by which we infer the causes of our successes and failures. We found that neuronal activity in the dorsolateral prefrontal cortex conveyed the necessary information for performing credit assignment. Importantly, while there are various potential mechanisms to retain a “trace” of the causal events over time, we observed that spiking activity was sufficiently stable to act as the link between causes and effects, in contrast to prior reports that suggested spiking representations were

  17. Comparing Looping Teacher-Assigned and Traditional Teacher-Assigned Student Achievement Scores

    ERIC Educational Resources Information Center

    Lloyd, Melissa C.

    2014-01-01

    A problem in many elementary schools is determining which teacher assignment strategy best promotes the academic progress of students. To find and implement educational practices that address the academic needs of all learners, schools need research-based data focusing on the 2 teacher assignment strategies: looping assignment (LA) and traditional…

  18. Grouping puts figure-ground assignment in context by constraining propagation of edge-assignment

    PubMed Central

    Brooks, Joseph L.; Driver, Jon

    2010-01-01

    Figure-ground organization involves assignment of edges to a figural shape on one or the other side of each dividing edge. Established visual cues for edge-assignment primarily concern relatively local rather than contextual factors. Here we show that assignment for a locally-unbiased edge can be affected by assignment of a remote contextual edge that has its own locally-biased assignment. We find that such propagation of edge-assignment from the biased remote context occurs only when the biased and unbiased edges are grouped. This new principle, whereby grouping constrains propagation of figural edge-assignment, emerges from both subjective reports and from an objective short-term edge-matching task. It generalizes from moving displays involving grouping by common fate and collinearity, to static displays with grouping by similarity of edge-contrast polarity, or apparent occlusion. Our results identify a new contextual influence upon edge-assignment. They also identify a new mechanistic relation between grouping and figure-ground processes, whereby grouping between remote elements can constrain propagation of edge-assignment between those elements. PMID:20436200

  19. Comparison of tissue adequacy for histologic examination from Ipas MVA plus and Wallach Endocell in women with abnormal uterine bleeding.

    PubMed

    Wanijasombutti, Paphada; Imruetaicharoenchok, Arinporn; Tangjitgamol, Siriwan; Loharamtaweethong, Kongsak; Phuriputt, Napaporn; Phaloprakarn, Chadakarn

    2015-08-01

    The aim of this study was to compare endometrial tissue adequacy sampling by Wallach Endocell and manual vacuum aspiration (Ipas MVA plus) in women with abnormal uterine bleeding. Pain and immediate complications from each method were also compared. Two hundred and forty women with abnormal uterine bleeding were randomly assigned to two methods of endometrial sampling: MVA (n = 122) and Endocell (n = 118). The basic characteristic features of the women, the difficulty of the procedure, pain score by visual analogue scale, immediate complications, and treatment were recorded. Endometrial tissue adequacy and histopathologic diagnoses were evaluated. The adequacy of tissue samples was 81.1% in the MVA group and 85.6% in the Endocell group (P = 0.356). There was a significant difference in the rates of difficult procedure between the two groups (27.0% in MVA vs 14.4% in Endocell; P = 0.016). Moderate to severe pain was significantly higher in the MVA group compared to the Endocell group: 60.7% and 19.5%, respectively (P < 0.001). Other immediate minor complications were also observed to be significantly higher in the MVA group (44.3%) than in the Endocell group (30.5%) (P = 0.028). Although medication required for pain was higher in the MVA group (23.0%) than in the Endocell group (12.0%), the difference was not significant (P = 0.130). The two most common histopathologic findings obtained from MVA and Endocell specimens were proliferative endometrium (32.4%) and atrophic endometrium (27.1%). MVA was comparable to Endocell in terms of tissue adequacy. Moderate to severe pain was experienced significantly more in the MVA group; however, the requirement of pain treatment was not significantly different between the groups. © 2015 The Authors Journal of Obstetrics and Gynaecology Research © 2015 Japan Society of Obstetrics and Gynecology.

  20. 75 FR 69126 - Proposed Information Collection Request (ICR) for the Workforce Investment Act Random Assignment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... Random Assignment Impact Evaluation of the Adult and Dislocated Worker Program; Comment Request AGENCY... fragmented system of employment and training programs under JTPA and providing universal access to basic (core) services. To determine whether the adult and dislocated worker services funded by Title I of the...

  1. Grouping puts figure-ground assignment in context by constraining propagation of edge assignment.

    PubMed

    Brooks, Joseph L; Brook, Joseph L; Driver, Jon

    2010-05-01

    Figure-ground organization involves the assignment of edges to a figural shape on one or the other side of each dividing edge. Established visual cues for edge assignment primarily concern relatively local rather than contextual factors. In the present article, we show that an assignment for a locally unbiased edge can be affected by an assignment of a remote contextual edge that has its own locally biased assignment. We find that such propagation of edge assignment from the biased remote context occurs only when the biased and unbiased edges are grouped. This new principle, whereby grouping constrains the propagation of figural edge assignment, emerges from both subjective reports and an objective short-term edge-matching task. It generalizes from moving displays involving grouping by common fate and collinearity, to static displays with grouping by similarity of edge-contrast polarity, or apparent occlusion. Our results identify a new contextual influence on edge assignment. They also identify a new mechanistic relation between grouping and figure-ground processes, whereby grouping between remote elements can constrain the propagation of edge assignment between those elements. Supplemental materials for this article may be downloaded from http://app.psychonomic-journals.org/content/supplemental.

  2. An Investigation of the Partial-Assignment Completion Effect on Students' Assignment Choice Behavior

    ERIC Educational Resources Information Center

    Hawthorn-Embree, Meredith L.; Skinner, Christopher H.; Parkhurst, John; Conley, Elisha

    2011-01-01

    This study was designed to investigate the partial assignment completion effect. Seventh-grade students were given a math assignment. After working for 5 min, they were interrupted and their partially completed assignments were collected. About 20 min later, students were given their partially completed assignment and a new, control assignment…

  3. 7 CFR 760.31 - Assignment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Assignment. No assignment shall be made of any indemnity payment due or to come due under the regulations in this subpart. Any assignment or attempted assignment of any indemnity payment due or to come due under...

  4. 7 CFR 760.31 - Assignment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Assignment. No assignment shall be made of any indemnity payment due or to come due under the regulations in this subpart. Any assignment or attempted assignment of any indemnity payment due or to come due under...

  5. 7 CFR 760.31 - Assignment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Assignment. No assignment shall be made of any indemnity payment due or to come due under the regulations in this subpart. Any assignment or attempted assignment of any indemnity payment due or to come due under...

  6. 7 CFR 760.31 - Assignment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Assignment. No assignment shall be made of any indemnity payment due or to come due under the regulations in this subpart. Any assignment or attempted assignment of any indemnity payment due or to come due under...

  7. 7 CFR 760.31 - Assignment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Assignment. No assignment shall be made of any indemnity payment due or to come due under the regulations in this subpart. Any assignment or attempted assignment of any indemnity payment due or to come due under...

  8. Implications of the Americans with Disabilities Act.

    ERIC Educational Resources Information Center

    Meservey, Lynne

    1993-01-01

    The Americans with Disabilities Act of 1990 (ADA) makes it unlawful to discriminate in all employee practices such as recruitment, hiring, promotion, training, benefits, pay, firing, job assignment, leave, lay-off, and all other employment-related activities. (PAM)

  9. 43 CFR 2806.21 - When and how are counties or other geographical areas assigned to a County Zone Number and Per...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... geographical areas assigned to a County Zone Number and Per Acre Zone Value? 2806.21 Section 2806.21 Public... MANAGEMENT ACT Rents Linear Rights-Of-Way § 2806.21 When and how are counties or other geographical areas assigned to a County Zone Number and Per Acre Zone Value? Counties (or other geographical areas) are...

  10. 43 CFR 2806.21 - When and how are counties or other geographical areas assigned to a County Zone Number and Per...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... geographical areas assigned to a County Zone Number and Per Acre Zone Value? 2806.21 Section 2806.21 Public... MANAGEMENT ACT Rents Linear Rights-Of-Way § 2806.21 When and how are counties or other geographical areas assigned to a County Zone Number and Per Acre Zone Value? Counties (or other geographical areas) are...

  11. 43 CFR 2806.21 - When and how are counties or other geographical areas assigned to a County Zone Number and Per...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... geographical areas assigned to a County Zone Number and Per Acre Zone Value? 2806.21 Section 2806.21 Public... MANAGEMENT ACT Rents Linear Rights-Of-Way § 2806.21 When and how are counties or other geographical areas assigned to a County Zone Number and Per Acre Zone Value? Counties (or other geographical areas) are...

  12. 43 CFR 2806.21 - When and how are counties or other geographical areas assigned to a County Zone Number and Per...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... geographical areas assigned to a County Zone Number and Per Acre Zone Value? 2806.21 Section 2806.21 Public... MANAGEMENT ACT Rents Linear Rights-Of-Way § 2806.21 When and how are counties or other geographical areas assigned to a County Zone Number and Per Acre Zone Value? Counties (or other geographical areas) are...

  13. 7 CFR 33.60 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE COMMODITY STANDARDS AND STANDARD CONTAINER REGULATIONS REGULATIONS ISSUED UNDER AUTHORITY OF THE EXPORT APPLE ACT...

  14. 77 FR 1088 - Secretary's Order 1-2011; Delegation of Authority and Assignment of Responsibilities to the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-09

    ... DEPARTMENT OF LABOR Office of the Secretary Secretary's Order 1-2011; Delegation of Authority and Assignment of Responsibilities to the Employee Benefits Security Administration 1. Purpose. To delegate... under the Employee Retirement Income Security Act of 1974 (ERISA), Federal Employees' Retirement System...

  15. 77 FR 5850 - Notice of Random Assignment Study To Evaluate Workforce Investment Act Adult and Dislocated...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-06

    ...: One commenter was concerned about 50 percent of the participants being placed in a control group. The... impact methodology for the evaluation. The design of the study was described as follows: The evaluation... eligible for intensive services would be randomly assigned to one of three groups. The three research...

  16. Protein Side-Chain Resonance Assignment and NOE Assignment Using RDC-Defined Backbones without TOCSY Data3

    PubMed Central

    Zeng, Jianyang; Zhou, Pei; Donald, Bruce Randall

    2011-01-01

    One bottleneck in NMR structure determination lies in the laborious and time-consuming process of side-chain resonance and NOE assignments. Compared to the well-studied backbone resonance assignment problem, automated side-chain resonance and NOE assignments are relatively less explored. Most NOE assignment algorithms require nearly complete side-chain resonance assignments from a series of through-bond experiments such as HCCH-TOCSY or HCCCONH. Unfortunately, these TOCSY experiments perform poorly on large proteins. To overcome this deficiency, we present a novel algorithm, called NASCA (NOE Assignment and Side-Chain Assignment), to automate both side-chain resonance and NOE assignments and to perform high-resolution protein structure determination in the absence of any explicit through-bond experiment to facilitate side-chain resonance assignment, such as HCCH-TOCSY. After casting the assignment problem into a Markov Random Field (MRF), NASCA extends and applies combinatorial protein design algorithms to compute optimal assignments that best interpret the NMR data. The MRF captures the contact map information of the protein derived from NOESY spectra, exploits the backbone structural information determined by RDCs, and considers all possible side-chain rotamers. The complexity of the combinatorial search is reduced by using a dead-end elimination (DEE) algorithm, which prunes side-chain resonance assignments that are provably not part of the optimal solution. Then an A* search algorithm is employed to find a set of optimal side-chain resonance assignments that best fit the NMR data. These side-chain resonance assignments are then used to resolve the NOE assignment ambiguity and compute high-resolution protein structures. Tests on five proteins show that NASCA assigns resonances for more than 90% of side-chain protons, and achieves about 80% correct assignments. The final structures computed using the NOE distance restraints assigned by NASCA have backbone RMSD 0

  17. 3 CFR - Assignment of Functions Under the National Defense Authorization Act for Fiscal Year 2010; the...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Defense Authorization Act for Fiscal Year 2010; the Department of Homeland Security Appropriations Act... detainees who will remain in the custody of the Department of Defense; 3. To the Attorney General, in... Department of Justice; 5. To the Attorney General, in consultation with the Secretary of Defense, the...

  18. Fair Package Assignment

    NASA Astrophysics Data System (ADS)

    Lahaie, Sébastien; Parkes, David C.

    We consider the problem of fair allocation in the package assignment model, where a set of indivisible items, held by single seller, must be efficiently allocated to agents with quasi-linear utilities. A fair assignment is one that is efficient and envy-free. We consider a model where bidders have superadditive valuations, meaning that items are pure complements. Our central result is that core outcomes are fair and even coalition-fair over this domain, while fair distributions may not even exist for general valuations. Of relevance to auction design, we also establish that the core is equivalent to the set of anonymous-price competitive equilibria, and that superadditive valuations are a maximal domain that guarantees the existence of anonymous-price competitive equilibrium. Our results are analogs of core equivalence results for linear prices in the standard assignment model, and for nonlinear, non-anonymous prices in the package assignment model with general valuations.

  19. 30 CFR 260.124 - How will royalty suspension apply if MMS assigns a lease issued in a sale held after November...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... assigns a lease issued in a sale held after November 2000 to a field that has a pre-Act lease? 260.124... royalty suspension apply if MMS assigns a lease issued in a sale held after November 2000 to a field that... suspension volume for a field as a result of an approved application for royalty relief submitted for a pre...

  20. Plagiarism-Proofing Assignments

    ERIC Educational Resources Information Center

    Johnson, Doug

    2004-01-01

    Mr. Johnson has discovered that the higher the level of student engagement and creativity, the lower the probability of plagiarism. For teachers who would like to see such desirable results, he describes the characteristics of assignments that are most likely to produce them. Two scenarios of types of assignments that avoid plagiarism are…

  1. 15 CFR 902.1 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... OF COMMERCE GENERAL REGULATIONS NOAA INFORMATION COLLECTION REQUIREMENTS UNDER THE PAPERWORK... collection requirements of the National Oceanic and Atmospheric Administration (NOAA) by the Office of Management and Budget (OMB) pursuant to the Paperwork Reduction Act (PRA). NOAA intends that this part comply...

  2. 15 CFR 902.1 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... OF COMMERCE GENERAL REGULATIONS NOAA INFORMATION COLLECTION REQUIREMENTS UNDER THE PAPERWORK... collection requirements of the National Oceanic and Atmospheric Administration (NOAA) by the Office of Management and Budget (OMB) pursuant to the Paperwork Reduction Act (PRA). NOAA intends that this part comply...

  3. 15 CFR 902.1 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... OF COMMERCE GENERAL REGULATIONS NOAA INFORMATION COLLECTION REQUIREMENTS UNDER THE PAPERWORK... collection requirements of the National Oceanic and Atmospheric Administration (NOAA) by the Office of Management and Budget (OMB) pursuant to the Paperwork Reduction Act (PRA). NOAA intends that this part comply...

  4. 15 CFR 902.1 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... OF COMMERCE GENERAL REGULATIONS NOAA INFORMATION COLLECTION REQUIREMENTS UNDER THE PAPERWORK... collection requirements of the National Oceanic and Atmospheric Administration (NOAA) by the Office of Management and Budget (OMB) pursuant to the Paperwork Reduction Act (PRA). NOAA intends that this part comply...

  5. 7 CFR 59.400 - OMB control number assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS... of this part have been approved by the Office of Management and Budget (OMB) under the provisions of...

  6. 7 CFR 58.100 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS... 7 CFR part 58, subpart B, by the Office of Management and Budget pursuant to the Paperwork Reduction...

  7. 7 CFR 52.59 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 PROCESSED FRUITS AND VEGETABLES, PROCESSED PRODUCTS... collection requirements contained in this part have been approved by the Office of Management and Budget (OMB...

  8. 15 CFR 902.1 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... OF COMMERCE GENERAL REGULATIONS NOAA INFORMATION COLLECTION REQUIREMENTS UNDER THE PAPERWORK... collection requirements of the National Oceanic and Atmospheric Administration (NOAA) by the Office of Management and Budget (OMB) pursuant to the Paperwork Reduction Act (PRA). NOAA intends that this part comply...

  9. 48 CFR 227.7010 - Assignments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF DEFENSE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Infringement Claims, Licenses, and Assignments 227.7010 Assignments. (a) The clause at 252.227-7011 is an example which may be used in contracts of assignment of patent rights to the Government. (b) To facilitate proof of...

  10. 7 CFR 58.64 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS... requirements in 7 CFR part 58, subpart A, by the Office of Management and Budget pursuant to the Paperwork...

  11. 7 CFR 54.1034 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS... collection requirements in 7 CFR part 54, subpart C, by the Office of Management and Budget pursuant to the...

  12. 20 CFR 670.450 - How are applicants who meet eligibility and selection criteria assigned to centers?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ADMINISTRATION, DEPARTMENT OF LABOR THE JOB CORPS UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Recruitment... center. The assignment plan is based on an analysis of: (1) The number of eligible individuals in the...) The demand for enrollment in Job Corps in the State and region where the center is located and in...

  13. 3 CFR - Establishment of the Interagency Committee on Trade in Timber Products from Peru and Assignment...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Establishment of the Interagency Committee on Trade in Timber Products from Peru and Assignment of Function under Section 501 of the United States-Peru Trade Promotion Agreement Implementation Act Presidential Documents Other Presidential Documents Memorandum of May 1, 2009 Establishment of the...

  14. 43 CFR 2521.3 - Assignment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Procedures § 2521.3 Assignment...), assignments of desert-land entries were recognized, the Department of the Interior, largely for administrative reasons, held that a desert-land entry might be assigned as a whole or in its entirety, but refused to...

  15. 43 CFR 2521.3 - Assignment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Procedures § 2521.3 Assignment...), assignments of desert-land entries were recognized, the Department of the Interior, largely for administrative reasons, held that a desert-land entry might be assigned as a whole or in its entirety, but refused to...

  16. 43 CFR 2521.3 - Assignment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Procedures § 2521.3 Assignment...), assignments of desert-land entries were recognized, the Department of the Interior, largely for administrative reasons, held that a desert-land entry might be assigned as a whole or in its entirety, but refused to...

  17. 43 CFR 2521.3 - Assignment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) DESERT-LAND ENTRIES Procedures § 2521.3 Assignment...), assignments of desert-land entries were recognized, the Department of the Interior, largely for administrative reasons, held that a desert-land entry might be assigned as a whole or in its entirety, but refused to...

  18. 78 FR 34354 - Privacy Act of 1974; System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-07

    ...(r) of the Privacy Act of 1974, as amended, was submitted on May 14, 2013, to the House Committee on... replace with ``System contains personnel data to support enlisted assignment, planning, programming...

  19. Evaluation of assigned-value uncertainty for complex calibrator value assignment processes: a prealbumin example.

    PubMed

    Middleton, John; Vaks, Jeffrey E

    2007-04-01

    Errors of calibrator-assigned values lead to errors in the testing of patient samples. The ability to estimate the uncertainties of calibrator-assigned values and other variables minimizes errors in testing processes. International Organization of Standardization guidelines provide simple equations for the estimation of calibrator uncertainty with simple value-assignment processes, but other methods are needed to estimate uncertainty in complex processes. We estimated the assigned-value uncertainty with a Monte Carlo computer simulation of a complex value-assignment process, based on a formalized description of the process, with measurement parameters estimated experimentally. This method was applied to study uncertainty of a multilevel calibrator value assignment for a prealbumin immunoassay. The simulation results showed that the component of the uncertainty added by the process of value transfer from the reference material CRM470 to the calibrator is smaller than that of the reference material itself (<0.8% vs 3.7%). Varying the process parameters in the simulation model allowed for optimizing the process, while keeping the added uncertainty small. The patient result uncertainty caused by the calibrator uncertainty was also found to be small. This method of estimating uncertainty is a powerful tool that allows for estimation of calibrator uncertainty for optimization of various value assignment processes, with a reduced number of measurements and reagent costs, while satisfying the requirements to uncertainty. The new method expands and augments existing methods to allow estimation of uncertainty in complex processes.

  20. 7 CFR 1250.501 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES... collection requirements by the Office of Management and Budget contained in 7 CFR part 1250 pursuant to the...-0098 1250.535 0581-0098 (Agricultural Marketing Act of 1946, as amended (7 U.S.C. 1621-1627) and Egg...

  1. Structural Case Assignment in Korean

    ERIC Educational Resources Information Center

    Koak, Heeshin

    2012-01-01

    In this dissertation, I aim to provide a theory on the distribution of structural Case in Korean. I propose the following Structural Case Assignment Hypothesis (SCAH) regarding the assignment of structural Case: "Structural Case is assigned by phase heads (C: nominative; v: accusative) to every argument in the c-command domain of the phase…

  2. AssignFit: a program for simultaneous assignment and structure refinement from solid-state NMR spectra

    PubMed Central

    Tian, Ye; Schwieters, Charles D.; Opella, Stanley J.; Marassi, Francesca M.

    2011-01-01

    AssignFit is a computer program developed within the XPLOR-NIH package for the assignment of dipolar coupling (DC) and chemical shift anisotropy (CSA) restraints derived from the solid-state NMR spectra of protein samples with uniaxial order. The method is based on minimizing the difference between experimentally observed solid-state NMR spectra and the frequencies back calculated from a structural model. Starting with a structural model and a set of DC and CSA restraints grouped only by amino acid type, as would be obtained by selective isotopic labeling, AssignFit generates all of the possible assignment permutations and calculates the corresponding atomic coordinates oriented in the alignment frame, together with the associated set of NMR frequencies, which are then compared with the experimental data for best fit. Incorporation of AssignFit in a simulated annealing refinement cycle provides an approach for simultaneous assignment and structure refinement (SASR) of proteins from solid-state NMR orientation restraints. The methods are demonstrated with data from two integral membrane proteins, one α-helical and one β-barrel, embedded in phospholipid bilayer membranes. PMID:22036904

  3. De-Coding Writing Assignments.

    ERIC Educational Resources Information Center

    Simon, Linda

    1991-01-01

    Argues that understanding assignments is the first step toward successful college writing. Urges instructors to support students by helping them to decode assignments. Breaks down instructions into individual tasks including (1) writing an essay, (2) examining an issue, (3) reviewing articles and books, and (4) focusing on some texts. Defines each…

  4. 47 CFR 74.1202 - Frequency assignment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... FM Broadcast Booster Stations § 74.1202 Frequency assignment. (a) An applicant for a new FM broadcast... broadcast booster station will be assigned the channel assigned to its primary station. [35 FR 15388, Oct. 2...

  5. 47 CFR 74.1202 - Frequency assignment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... FM Broadcast Booster Stations § 74.1202 Frequency assignment. (a) An applicant for a new FM broadcast... broadcast booster station will be assigned the channel assigned to its primary station. [35 FR 15388, Oct. 2...

  6. 47 CFR 74.1202 - Frequency assignment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... FM Broadcast Booster Stations § 74.1202 Frequency assignment. (a) An applicant for a new FM broadcast... broadcast booster station will be assigned the channel assigned to its primary station. [35 FR 15388, Oct. 2...

  7. 47 CFR 74.1202 - Frequency assignment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... FM Broadcast Booster Stations § 74.1202 Frequency assignment. (a) An applicant for a new FM broadcast... broadcast booster station will be assigned the channel assigned to its primary station. [35 FR 15388, Oct. 2...

  8. Optimal processor assignment for pipeline computations

    NASA Technical Reports Server (NTRS)

    Nicol, David M.; Simha, Rahul; Choudhury, Alok N.; Narahari, Bhagirath

    1991-01-01

    The availability of large scale multitasked parallel architectures introduces the following processor assignment problem for pipelined computations. Given a set of tasks and their precedence constraints, along with their experimentally determined individual responses times for different processor sizes, find an assignment of processor to tasks. Two objectives are of interest: minimal response given a throughput requirement, and maximal throughput given a response time requirement. These assignment problems differ considerably from the classical mapping problem in which several tasks share a processor; instead, it is assumed that a large number of processors are to be assigned to a relatively small number of tasks. Efficient assignment algorithms were developed for different classes of task structures. For a p processor system and a series parallel precedence graph with n constituent tasks, an O(np2) algorithm is provided that finds the optimal assignment for the response time optimization problem; it was found that the assignment optimizing the constrained throughput in O(np2log p) time. Special cases of linear, independent, and tree graphs are also considered.

  9. Optimizing Marine Security Guard Assignments

    DTIC Science & Technology

    2011-06-01

    Bangkok, Thailand East Asia and Pacific 18 4 Fort Lauderdale, Florida Western Hemisphere - South 13 5 Frankfurt, Germany Western Europe and Scandinavia 15...Marine-billet assignment using similar fit criteria, such as rank and gender . 3. Minimize the amount of movement when filling the billets. That is, their...more than once. Gender Female MSGs will not be assigned to embassies that are not configured for females. DC Only DC-qualified MSGs are assigned to DC

  10. 20 CFR 332.6 - Standing by for and laying over between regularly assigned trips or tours of duty.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Standing by for and laying over between regularly assigned trips or tours of duty. 332.6 Section 332.6 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD UNEMPLOYMENT INSURANCE ACT MILEAGE OR WORK RESTRICTIONS AND STAND-BY OR LAY...

  11. [IPA secretary and patron--Freud's patient, financial administrator and friend. Anton von Freund's letters to Sigmund Freud (1916-1919)].

    PubMed

    Huppke, Andrea; Schröter, Michael

    2011-01-01

    Although the letters, of which numerous and lengthy excerpts are presented in this paper, have repeatedly been used by scholars, they have so far remained unpublished. There are 45 items, written between 4. 1. 1916 and 13. 7. 1919. They indicate a passionate transference to Freud, unfolding against the background of two Hungarian revolutions. After suffering a relapse of his cancer, v. Freund had several stretches of analysis with Freud. While he was better, he established two major funds: one of them allowing the foundation of the psychoanalytic publishing house, the other destined to sponsor a psychoanalytic clinic in Budapest. V. Freund helped organize the Budapest IPA congress, became a member of the "secret committee" and started to actively conduct analyses. Freud was very attached to him and felt deeply shaken by the inexorable progression of v. Freund's disease and then death in January 1920.

  12. Towards Automated Structure-Based NMR Resonance Assignment

    NASA Astrophysics Data System (ADS)

    Jang, Richard; Gao, Xin; Li, Ming

    We propose a general framework for solving the structure-based NMR backbone resonance assignment problem. The core is a novel 0-1 integer programming model that can start from a complete or partial assignment, generate multiple assignments, and model not only the assignment of spins to residues, but also pairwise dependencies consisting of pairs of spins to pairs of residues. It is still a challenge for automated resonance assignment systems to perform the assignment directly from spectra without any manual intervention. To test the feasibility of this for structure-based assignment, we integrated our system with our automated peak picking and sequence-based resonance assignment system to obtain an assignment for the protein TM1112 with 91% recall and 99% precision without manual intervention. Since using a known structure has the potential to allow one to use only N-labeled NMR data and avoid the added expense of using C-labeled data, we work towards the goal of automated structure-based assignment using only such labeled data. Our system reduced the assignment error of Xiong-Pandurangan-Bailey-Kellogg's contact replacement (CR) method, which to our knowledge is the most error-tolerant method for this problem, by 5 folds on average. By using an iterative algorithm, our system has the added capability of using the NOESY data to correct assignment errors due to errors in predicting the amino acid and secondary structure type of each spin system. On a publicly available data set for Ubiquitin, where the type prediction accuracy is 83%, we achieved 91% assignment accuracy, compared to the 59% accuracy that was obtained without correcting for typing errors.

  13. Adaptable Assignment

    DOT National Transportation Integrated Search

    1997-01-01

    This paper reports on a practical, simple method for adjusting a vehicle trip table so that the resulting assignments more closely match available traffic counts. "Practical" means that this is not purely a research effort - the procedure described h...

  14. Real life working shift assignment problem

    NASA Astrophysics Data System (ADS)

    Sze, San-Nah; Kwek, Yeek-Ling; Tiong, Wei-King; Chiew, Kang-Leng

    2017-07-01

    This study concerns about the working shift assignment in an outlet of Supermarket X in Eastern Mall, Kuching. The working shift assignment needs to be solved at least once in every month. Current approval process of working shifts is too troublesome and time-consuming. Furthermore, the management staff cannot have an overview of manpower and working shift schedule. Thus, the aim of this study is to develop working shift assignment simulation and propose a working shift assignment solution. The main objective for this study is to fulfill manpower demand at minimum operation cost. Besides, the day off and meal break policy should be fulfilled accordingly. Demand based heuristic is proposed to assign working shift and the quality of the solution is evaluated by using the real data.

  15. 28 CFR 301.103 - Inmate work assignments.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Inmate work assignments. 301.103 Section... COMPENSATION General § 301.103 Inmate work assignments. The unit team of each inmate, which ordinarily designates work assignments, or whoever makes work assignments, shall review appropriate medical records...

  16. 28 CFR 301.103 - Inmate work assignments.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Inmate work assignments. 301.103 Section... COMPENSATION General § 301.103 Inmate work assignments. The unit team of each inmate, which ordinarily designates work assignments, or whoever makes work assignments, shall review appropriate medical records...

  17. 28 CFR 301.103 - Inmate work assignments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Inmate work assignments. 301.103 Section... COMPENSATION General § 301.103 Inmate work assignments. The unit team of each inmate, which ordinarily designates work assignments, or whoever makes work assignments, shall review appropriate medical records...

  18. 28 CFR 301.103 - Inmate work assignments.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Inmate work assignments. 301.103 Section... COMPENSATION General § 301.103 Inmate work assignments. The unit team of each inmate, which ordinarily designates work assignments, or whoever makes work assignments, shall review appropriate medical records...

  19. 28 CFR 544.74 - Work assignment limitations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Work assignment limitations. 544.74... EDUCATION Literacy Program § 544.74 Work assignment limitations. These limitations on work assignment... order to be considered for a commissary work assignment above minimum pay level, an institution work...

  20. 20 CFR 243.5 - Assignment of a portion of an annuity paid under the social security overall minimum provision.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... under the social security overall minimum provision. 243.5 Section 243.5 Employees' Benefits RAILROAD... § 243.5 Assignment of a portion of an annuity paid under the social security overall minimum provision. Section 3(f)(3) of the Railroad Retirement Act, the social security overall minimum provision, guarantees...

  1. 20 CFR 243.5 - Assignment of a portion of an annuity paid under the social security overall minimum provision.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... under the social security overall minimum provision. 243.5 Section 243.5 Employees' Benefits RAILROAD... § 243.5 Assignment of a portion of an annuity paid under the social security overall minimum provision. Section 3(f)(3) of the Railroad Retirement Act, the social security overall minimum provision, guarantees...

  2. 20 CFR 243.5 - Assignment of a portion of an annuity paid under the social security overall minimum provision.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... under the social security overall minimum provision. 243.5 Section 243.5 Employees' Benefits RAILROAD... § 243.5 Assignment of a portion of an annuity paid under the social security overall minimum provision. Section 3(f)(3) of the Railroad Retirement Act, the social security overall minimum provision, guarantees...

  3. DSSPcont: continuous secondary structure assignments for proteins

    PubMed Central

    Carter, Phil; Andersen, Claus A. F.; Rost, Burkhard

    2003-01-01

    The DSSP program automatically assigns the secondary structure for each residue from the three-dimensional co-ordinates of a protein structure to one of eight states. However, discrete assignments are incomplete in that they cannot capture the continuum of thermal fluctuations. Therefore, DSSPcont (http://cubic.bioc.columbia.edu/services/DSSPcont) introduces a continuous assignment of secondary structure that replaces ‘static’ by ‘dynamic’ states. Technically, the continuum results from calculating weighted averages over 10 discrete DSSP assignments with different hydrogen bond thresholds. A DSSPcont assignment for a particular residue is a percentage likelihood of eight secondary structure states, derived from a weighted average of the ten DSSP assignments. The continuous assignments have two important features: (i) they reflect the structural variations due to thermal fluctuations as detected by NMR spectroscopy; and (ii) they reproduce the structural variation between many NMR models from one single model. Therefore, functionally important variation can be extracted from a single X-ray structure using the continuous assignment procedure. PMID:12824310

  4. 24 CFR 221.770 - Assignment option.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Assignment option. 221.770 Section... § 221.770 Assignment option. A mortgagee holding a conditional or firm commitment issued on or before... mortgagee's approved underwriter on or before November 30, 1983) has the option to assign, transfer and...

  5. 24 CFR 221.255 - Assignment option.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Assignment option. 221.255 Section... Assignment option. (a) A mortgagee holding a mortgage insured pursuant to a conditional or firm commitment issued on or before November 30, 1983 has the option to assign, transfer and deliver to the Commissioner...

  6. 48 CFR 1552.211-74 - Work assignments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Work assignments. 1552.211... Work assignments. As prescribed in 1511.011-74, insert the following contract clause in cost-reimbursement type term form contracts when work assignments are to be used. Work Assignments (APR 1984) (a) The...

  7. 7 CFR 1700.53 - Persons serving as Acting Administrator.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) Eligibility for succession to the position of RUS Administrator shall be limited to officially assigned... the approved order of succession are eligible. Persons appointed on acting basis, or on some other... succession would fall to the next designated official in the approved order of succession. The eligibility of...

  8. 7 CFR 1700.53 - Persons serving as Acting Administrator.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) Eligibility for succession to the position of RUS Administrator shall be limited to officially assigned... the approved order of succession are eligible. Persons appointed on acting basis, or on some other... succession would fall to the next designated official in the approved order of succession. The eligibility of...

  9. 7 CFR 1700.53 - Persons serving as Acting Administrator.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) Eligibility for succession to the position of RUS Administrator shall be limited to officially assigned... the approved order of succession are eligible. Persons appointed on acting basis, or on some other... succession would fall to the next designated official in the approved order of succession. The eligibility of...

  10. 7 CFR 1700.53 - Persons serving as Acting Administrator.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) Eligibility for succession to the position of RUS Administrator shall be limited to officially assigned... the approved order of succession are eligible. Persons appointed on acting basis, or on some other... succession would fall to the next designated official in the approved order of succession. The eligibility of...

  11. 7 CFR 1700.53 - Persons serving as Acting Administrator.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) Eligibility for succession to the position of RUS Administrator shall be limited to officially assigned... the approved order of succession are eligible. Persons appointed on acting basis, or on some other... succession would fall to the next designated official in the approved order of succession. The eligibility of...

  12. NMR resonance assignments of the lantibiotic immunity protein NisI from Lactococcus lactis.

    PubMed

    Hacker, Carolin; Christ, Nina Alexandra; Duchardt-Ferner, Elke; Korn, Sophie; Berninger, Lucija; Kötter, Peter; Entian, Karl-Dieter; Wöhnert, Jens

    2015-10-01

    The lantibiotic nisin is a small antimicrobial peptide which acts against a wide range of Gram-positive bacteria. Nisin-producing Lactococcus lactis strains express four genes for self-protection against their own antimicrobial compound. This immunity system consists of the lipoprotein NisI and the ABC transporter NisFEG. NisI is attached to the outside of the cytoplasmic membrane via a covalently linked diacylglycerol anchor. Both the lipoprotein and the ABC transporter are needed for full immunity but the exact immunity mechanism is still unclear. To gain insights into the highly specific immunity mechanism of nisin producing strains on a structural level we present here the backbone resonance assignment of NisI (25.8 kDa) as well as the virtually complete (1)H,(15)N,(13)C chemical shift assignments for the isolated 12.7 kDa N-terminal and 14.6 kDa C-terminal domains of NisI.

  13. Replicating and Extending Research on the Partial Assignment Completion Effect: Is Sunk Cost Related to Partial Assignment Completion Strength?

    ERIC Educational Resources Information Center

    Hawthorn-Embree, Meredith L.; Taylor, Emily P.; Skinner, Christopher H.; Parkhurst, John; Nalls, Meagan L.

    2014-01-01

    After students acquire a skill, mastery often requires them to choose to engage in assigned academic activities (e.g., independent seatwork, and homework). Although students may be more likely to choose to work on partially completed assignments than on new assignments, the partial assignment completion (PAC) effect may not be very powerful. The…

  14. 75 FR 58368 - Privacy Act of 1974; System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... DEPARTMENT OF DEFENSE Office of the Secretary [Docket ID DOD-2010-OS-0125] Privacy Act of 1974... Register Liaison Officer, Department of Defense. ZDO-001 System name: Accountability Records/Recall Rosters... commissaries, including Department of Defense (DoD) Federal employees, military service personnel not assigned...

  15. PERSONAL AND CIRCUMSTANTIAL FACTORS INFLUENCING THE ACT OF DISCOVERY.

    ERIC Educational Resources Information Center

    OSTRANDER, EDWARD R.

    HOW STUDENTS SAY THEY LEARN WAS INVESTIGATED. INTERVIEWS WITH A RANDOM SAMPLE OF 74 WOMEN STUDENTS POSED QUESTIONS ABOUT THE NATURE, FREQUENCY, PATTERNS, AND CIRCUMSTANCES UNDER WHICH ACTS OF DISCOVERY TAKE PLACE IN THE ACADEMIC SETTING. STUDENTS WERE ASSIGNED DISCOVERY RATINGS BASED ON READINGS OF TYPESCRIPTS. EACH STUDENT WAS CLASSIFIED AND…

  16. 7 CFR 784.15 - Assignments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Assignments. 784.15 Section 784.15 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS 2004 EWE LAMB REPLACEMENT AND RETENTION PAYMENT PROGRAM § 784.15 Assignments. Any person...

  17. Drafting and acting on feedback supports student learning when writing essay assignments.

    PubMed

    Freestone, Nicholas

    2009-06-01

    A diverse student population is a relatively recent feature of the higher education system in the United Kingdom. Consequently, it may be thought that more "traditional" types of assessment based around essay writing skills for science undergraduates may be of decreasing value and relevance to contemporary students. This article describes a study in which the process of feedback on, and associated redrafting of, an essay was closely supervised to improve essay writing skills and subsequent exam performance. The results of this study show that students can significantly improve their learning and academic performance, as assessed by final examination mark, by a process that more closely mimics a "real-world" situation of review and redrafting. Additionally, the data show that students benefit from feedback only when this is used appropriately by the student. The article also discusses the continuing importance and relevance of essay writing skills so that writing, and acting upon feedback to do with that writing, remains an integral part of the process of learning.

  18. ACTS High-Speed VSAT Demonstrated

    NASA Technical Reports Server (NTRS)

    Tran, Quang K.

    1999-01-01

    The Advanced Communication Technology Satellite (ACTS) developed by NASA has demonstrated the breakthrough technologies of Ka-band transmission, spot-beam antennas, and onboard processing. These technologies have enabled the development of very small and ultrasmall aperture terminals (VSAT s and USAT's), which have capabilities greater than have been possible with conventional satellite technologies. The ACTS High Speed VSAT (HS VSAT) is an effort at the NASA Glenn Research Center at Lewis Field to experimentally demonstrate the maximum user throughput data rate that can be achieved using the technologies developed and implemented on ACTS. This was done by operating the system uplinks as frequency division multiple access (FDMA), essentially assigning all available time division multiple access (TDMA) time slots to a single user on each of two uplink frequencies. Preliminary results show that, using a 1.2-m antenna in this mode, the High Speed VSAT can achieve between 22 and 24 Mbps of the 27.5 Mbps burst rate, for a throughput efficiency of 80 to 88 percent.

  19. Consensus Assignments for Water Vapor Lines Not Assigned on the HITRAN Database: 13,200 to 16,500/cm

    NASA Technical Reports Server (NTRS)

    Giver, Lawerence P.; Chackerian, Charles, Jr.; Freedman, Richard S.; Varanasi, Prasad; Gore, Warren (Technical Monitor)

    2000-01-01

    There are nearly 800 water Vapor-lines in the 13,200-16,500/cm region that do not have rovibrational assignments in the HITRAN database. The positions and intensities in the database were determined by Mandin et al., but assignments could not be determined at that time. Polyansky, et al. have now assigned over 600 of the unassigned lines in the 11,200-16,500/cm region. Schwenke has also given rovibrational assignments to many of these unassigned lines throughout the visible and near-infrared. Both articles changed the assignments of some HITRAN lines. Carleer et al. extend assignments to some weaker lines measured by them on new spectra with excellent signal/noise. However, some lines measured by Mandin et al. were omitted by Carleer, et al. because of blends due to lower spectral resolution. The rovibrational assignments of Polyansky et al. completely agree with those in Schwenke's article for only about 200 lines. However, Schwenke's ab initio line list is available on his internet site (http://ccf.arc.nasa.gov/-dschwenke). A detailed comparison of the Polyansky et al.line list, the Carleer et al.line list, and Schwenke's ab initio line list shows a larger number of agreements. In many cases the disagreement is only about the vibrational and/or rotational upper level, while there is agreement on the lower state assignment and energy level, "E", which is of primary importance for atmospheric applications. We will present a line list of "consensus" assignments in the 13,200-16,500/cm region for consideration of inclusion on the HITRAN and GEISA databases. This will substantially reduce the number of unassigned lines on the databases in this spectral region.

  20. Problematic Drinking Mediates the Association Between Urgency and Intimate Partner Aggression During Acute Intoxication.

    PubMed

    Subramani, Olivia S; Parrott, Dominic J; Eckhardt, Christopher I

    2017-09-01

    This study tested a moderated-mediation model whereby dimensions of impulsivity (i.e., negative urgency, positive urgency, sensation seeking, lack of premeditation, and lack of perseverance) differentially predict perpetration of physical intimate partner aggression (IPA) through problematic drinking in intoxicated and nonintoxicated heavy drinkers. Participants were 249 heavy drinkers (148 men and 101 women) with a recent history of psychological and/or physical IPA perpetration toward their current partner recruited from 2 metropolitan U.S. cities. Participants completed questionnaires that assessed impulsivity and problematic drinking, consumed an Alcohol or No-Alcohol Control beverage, and completed a shock-based aggression task in which they were ostensibly provoked by their intimate partner. Results indicated an indirect effect of urgency on IPA through problematic drinking that was significantly more positive in intoxicated individuals. These findings implicate a tendency to act rashly in response to emotions as the specific dimension of impulsivity associated with problematic drinking, which in turn exacerbates risk for IPA perpetration. Results also suggest acute effects of alcohol are key in facilitating this mechanism. Copyright © 2017 by the Research Society on Alcoholism.

  1. 25 CFR 535.2 - Assignments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Assignments. 535.2 Section 535.2 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR MANAGEMENT CONTRACT PROVISIONS POST-APPROVAL PROCEDURES... disapprove an assignment applying the standards of, and within the time provided by §§ 535.1(d) and 535.1(e...

  2. Would introverts be better off if they acted more like extraverts? Exploring emotional and cognitive consequences of counterdispositional behavior.

    PubMed

    Zelenski, John M; Santoro, Maya S; Whelan, Deanna C

    2012-04-01

    People enjoy acting extraverted, and this seems to apply equally across the dispositional introversion-extraversion dimension (Fleeson, Malanos, & Achille, 2002). It follows that dispositional introverts might improve their happiness by acting more extraverted, yet little research has examined potential costs of this strategy. In two studies, we assessed dispositions, randomly assigned participants to act introverted or extraverted, and examined costs-both emotional (concurrent negative affect) and cognitive (Stroop performance). Results replicated and extended past findings suggesting that acting extraverted produces hedonic benefits regardless of disposition. Positive affect increased and negative affect did not, even for participants acting out of character. In contrast, we found evidence that acting counterdispositionally could produce poor Stroop performance, but this effect was limited to dispositional extraverts who were assigned to act introverted. We suggest that the positive affect produced by introverts' extraverted behavior may buffer the potentially depleting effects of counterdispositional behavior, and we consider alternative explanations. We conclude that dispositional introverts may indeed benefit from acting extraverted more often and caution that dispositional extraverts may want to adopt introverted behavior strategically, as it could induce cognitive costs or self-regulatory depletion more generally. (PsycINFO Database Record (c) 2012 APA, all rights reserved).

  3. 5 CFR 351.701 - Assignment involving displacement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Assignment involving displacement. 351.701 Section 351.701 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS REDUCTION IN FORCE Assignment Rights (Bump and Retreat) § 351.701 Assignment involving displacement. (a...

  4. 5 CFR 351.701 - Assignment involving displacement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Assignment involving displacement. 351.701 Section 351.701 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS REDUCTION IN FORCE Assignment Rights (Bump and Retreat) § 351.701 Assignment involving displacement. (a...

  5. 5 CFR 351.701 - Assignment involving displacement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Assignment involving displacement. 351.701 Section 351.701 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS REDUCTION IN FORCE Assignment Rights (Bump and Retreat) § 351.701 Assignment involving displacement. (a...

  6. 5 CFR 351.701 - Assignment involving displacement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Assignment involving displacement. 351.701 Section 351.701 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS REDUCTION IN FORCE Assignment Rights (Bump and Retreat) § 351.701 Assignment involving displacement. (a...

  7. 5 CFR 351.701 - Assignment involving displacement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Assignment involving displacement. 351.701 Section 351.701 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS REDUCTION IN FORCE Assignment Rights (Bump and Retreat) § 351.701 Assignment involving displacement. (a...

  8. 7 CFR 900.106 - Assignment of mediator.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Assignment of mediator. 900.106 Section 900.106 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Assignment of mediator. The Director of the Division shall assign a mediator, from the group designated by...

  9. 48 CFR 1511.011-74 - Work assignments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Work assignments. 1511.011... ACQUISITION PLANNING DESCRIBING AGENCY NEEDS 1511.011-74 Work assignments. The Contracting Officer shall insert the contract clause at 1552.211-74, Work Assignments, in cost-reimbursement type term form...

  10. 75 FR 65007 - Privacy Act of 1974; System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-21

    ... DEPARTMENT OF DEFENSE Department of the Air Force [Docket ID: USAF-2010-0027] Privacy Act of 1974... Special Investigations (AFOSI). Also includes AFOSI personnel assigned to any Department of Defense (DoD... therein may be specifically disclosed outside the Department of Defense as a routine use pursuant to 5 U.S...

  11. 48 CFR 1552.211-74 - Work assignments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-reimbursement type term form contracts when work assignments are to be used. Work Assignments (APR 1984) (a) The... assignment or similar tasking document, the Contractor shall provide a conflict of interest certification... directly related to a site, the Contractor is only required to provide a conflict of interest certification...

  12. Lexical Stress Assignment in Italian Developmental Dyslexia

    ERIC Educational Resources Information Center

    Paizi, Despina; Zoccolotti, Pierluigi; Burani, Cristina

    2011-01-01

    Stress assignment to Italian polysyllabic words is unpredictable, because stress is neither marked nor predicted by rule. Stress assignment, especially to low frequency words, has been reported to be a function of stress dominance and stress neighbourhood. Two experiments investigate stress assignment in sixth-grade, skilled and dyslexic, readers.…

  13. 29 CFR 1403.4 - Assignment of mediators.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Assignment of mediators. 1403.4 Section 1403.4 Labor Regulations Relating to Labor (Continued) FEDERAL MEDIATION AND CONCILIATION SERVICE FUNCTIONS AND DUTIES § 1403.4 Assignment of mediators. The Federal Service will assign one or more mediators to each labor...

  14. Evaluation of Automatically Assigned Job-Specific Interview Modules.

    PubMed

    Friesen, Melissa C; Lan, Qing; Ge, Calvin; Locke, Sarah J; Hosgood, Dean; Fritschi, Lin; Sadkowsky, Troy; Chen, Yu-Cheng; Wei, Hu; Xu, Jun; Lam, Tai Hing; Kwong, Yok Lam; Chen, Kexin; Xu, Caigang; Su, Yu-Chieh; Chiu, Brian C H; Ip, Kai Ming Dennis; Purdue, Mark P; Bassig, Bryan A; Rothman, Nat; Vermeulen, Roel

    2016-08-01

    In community-based epidemiological studies, job- and industry-specific 'modules' are often used to systematically obtain details about the subject's work tasks. The module assignment is often made by the interviewer, who may have insufficient occupational hygiene knowledge to assign the correct module. We evaluated, in the context of a case-control study of lymphoid neoplasms in Asia ('AsiaLymph'), the performance of an algorithm that provided automatic, real-time module assignment during a computer-assisted personal interview. AsiaLymph's occupational component began with a lifetime occupational history questionnaire with free-text responses and three solvent exposure screening questions. To assign each job to one of 23 study-specific modules, an algorithm automatically searched the free-text responses to the questions 'job title' and 'product made or services provided by employer' using a list of module-specific keywords, comprising over 5800 keywords in English, Traditional and Simplified Chinese. Hierarchical decision rules were used when the keyword match triggered multiple modules. If no keyword match was identified, a generic solvent module was assigned if the subject responded 'yes' to any of the three solvent screening questions. If these question responses were all 'no', a work location module was assigned, which redirected the subject to the farming, teaching, health professional, solvent, or industry solvent modules or ended the questions for that job, depending on the location response. We conducted a reliability assessment that compared the algorithm-assigned modules to consensus module assignments made by two industrial hygienists for a subset of 1251 (of 11409) jobs selected using a stratified random selection procedure using module-specific strata. Discordant assignments between the algorithm and consensus assignments (483 jobs) were qualitatively reviewed by the hygienists to evaluate the potential information lost from missed questions with using

  15. 7 CFR 97.130 - Recording of assignments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... PLANT VARIETY AND PROTECTION Assignments and Recording § 97.130 Recording of assignments. (a) Any assignment of an application for a certificate, or of a certificate of plant variety protection, or of any interest in a variety, or any license or grant and conveyance of any right to use of the variety, may be...

  16. 20 CFR 670.420 - Are there any special requirements for enrollment related to the Military Selective Service Act?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Are there any special requirements for enrollment related to the Military Selective Service Act? 670.420 Section 670.420 Employees' Benefits... INVESTMENT ACT Recruitment, Eligibility, Screening, Selection and Assignment, and Enrollment § 670.420 Are...

  17. 20 CFR 411.220 - What if my ticket is no longer assigned to an EN or State VR agency?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... EN or State VR agency? 411.220 Section 411.220 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE... or State VR agency? (a) If your ticket was once assigned to an EN or State VR agency acting as an EN... § 411.145(a)) or because you relocated to an area not served by your previous EN or State VR agency; or...

  18. 20 CFR 411.220 - What if my ticket is no longer assigned to an EN or State VR agency?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... EN or State VR agency? 411.220 Section 411.220 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE... or State VR agency? (a) If your ticket was once assigned to an EN or State VR agency acting as an EN... § 411.145(a)) or because you relocated to an area not served by your previous EN or State VR agency; or...

  19. 20 CFR 411.220 - What if my ticket is no longer assigned to an EN or State VR agency?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... EN or State VR agency? 411.220 Section 411.220 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE... or State VR agency? (a) If your ticket was once assigned to an EN or State VR agency acting as an EN... § 411.145(a)) or because you relocated to an area not served by your previous EN or State VR agency; or...

  20. 20 CFR 411.220 - What if my ticket is no longer assigned to an EN or State VR agency?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... EN or State VR agency? 411.220 Section 411.220 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE... or State VR agency? (a) If your ticket was once assigned to an EN or State VR agency acting as an EN... § 411.145(a)) or because you relocated to an area not served by your previous EN or State VR agency; or...

  1. 20 CFR 411.220 - What if my ticket is no longer assigned to an EN or State VR agency?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... EN or State VR agency? 411.220 Section 411.220 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE... or State VR agency? (a) If your ticket was once assigned to an EN or State VR agency acting as an EN... § 411.145(a)) or because you relocated to an area not served by your previous EN or State VR agency; or...

  2. Theoretical and subjective bit assignments in transform picture

    NASA Technical Reports Server (NTRS)

    Jones, H. W., Jr.

    1977-01-01

    It is shown that all combinations of symmetrical input distributions with difference distortion measures give a bit assignment rule identical to the well-known rule for a Gaussian input distribution with mean-square error. Published work is examined to show that the bit assignment rule is useful for transforms of full pictures, but subjective bit assignments for transform picture coding using small block sizes are significantly different from the theoretical bit assignment rule. An intuitive explanation is based on subjective design experience, and a subjectively obtained bit assignment rule is given.

  3. Evaluation of Automatically Assigned Job-Specific Interview Modules

    PubMed Central

    Friesen, Melissa C.; Lan, Qing; Ge, Calvin; Locke, Sarah J.; Hosgood, Dean; Fritschi, Lin; Sadkowsky, Troy; Chen, Yu-Cheng; Wei, Hu; Xu, Jun; Lam, Tai Hing; Kwong, Yok Lam; Chen, Kexin; Xu, Caigang; Su, Yu-Chieh; Chiu, Brian C. H.; Ip, Kai Ming Dennis; Purdue, Mark P.; Bassig, Bryan A.; Rothman, Nat; Vermeulen, Roel

    2016-01-01

    Objective: In community-based epidemiological studies, job- and industry-specific ‘modules’ are often used to systematically obtain details about the subject’s work tasks. The module assignment is often made by the interviewer, who may have insufficient occupational hygiene knowledge to assign the correct module. We evaluated, in the context of a case–control study of lymphoid neoplasms in Asia (‘AsiaLymph’), the performance of an algorithm that provided automatic, real-time module assignment during a computer-assisted personal interview. Methods: AsiaLymph’s occupational component began with a lifetime occupational history questionnaire with free-text responses and three solvent exposure screening questions. To assign each job to one of 23 study-specific modules, an algorithm automatically searched the free-text responses to the questions ‘job title’ and ‘product made or services provided by employer’ using a list of module-specific keywords, comprising over 5800 keywords in English, Traditional and Simplified Chinese. Hierarchical decision rules were used when the keyword match triggered multiple modules. If no keyword match was identified, a generic solvent module was assigned if the subject responded ‘yes’ to any of the three solvent screening questions. If these question responses were all ‘no’, a work location module was assigned, which redirected the subject to the farming, teaching, health professional, solvent, or industry solvent modules or ended the questions for that job, depending on the location response. We conducted a reliability assessment that compared the algorithm-assigned modules to consensus module assignments made by two industrial hygienists for a subset of 1251 (of 11409) jobs selected using a stratified random selection procedure using module-specific strata. Discordant assignments between the algorithm and consensus assignments (483 jobs) were qualitatively reviewed by the hygienists to evaluate the potential

  4. 48 CFR 208.7002 - Assignment authority.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... activities concerned. (b) Under the Integrated Materiel Management Program, assignments are made by the... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false Assignment authority. 208.7002 Section 208.7002 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM...

  5. 48 CFR 208.7002 - Assignment authority.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... activities concerned. (b) Under the Integrated Materiel Management Program, assignments are made by the... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false Assignment authority. 208.7002 Section 208.7002 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM...

  6. 48 CFR 208.7002 - Assignment authority.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... activities concerned. (b) Under the Integrated Materiel Management Program, assignments are made by the... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Assignment authority. 208.7002 Section 208.7002 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM...

  7. 48 CFR 208.7002 - Assignment authority.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... activities concerned. (b) Under the Integrated Materiel Management Program, assignments are made by the... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false Assignment authority. 208.7002 Section 208.7002 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM...

  8. Joint Inference of Population Assignment and Demographic History

    PubMed Central

    Choi, Sang Chul; Hey, Jody

    2011-01-01

    A new approach to assigning individuals to populations using genetic data is described. Most existing methods work by maximizing Hardy–Weinberg and linkage equilibrium within populations, neither of which will apply for many demographic histories. By including a demographic model, within a likelihood framework based on coalescent theory, we can jointly study demographic history and population assignment. Genealogies and population assignments are sampled from a posterior distribution using a general isolation-with-migration model for multiple populations. A measure of partition distance between assignments facilitates not only the summary of a posterior sample of assignments, but also the estimation of the posterior density for the demographic history. It is shown that joint estimates of assignment and demographic history are possible, including estimation of population phylogeny for samples from three populations. The new method is compared to results of a widely used assignment method, using simulated and published empirical data sets. PMID:21775468

  9. 28 CFR 548.17 - Work assignments.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Work assignments. 548.17 Section 548.17 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT RELIGIOUS PROGRAMS Religious Beliefs and Practices of Committed Offenders § 548.17 Work assignments. When the...

  10. 28 CFR 548.17 - Work assignments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Work assignments. 548.17 Section 548.17 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT RELIGIOUS PROGRAMS Religious Beliefs and Practices of Committed Offenders § 548.17 Work assignments. When the...

  11. 28 CFR 548.17 - Work assignments.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Work assignments. 548.17 Section 548.17 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT RELIGIOUS PROGRAMS Religious Beliefs and Practices of Committed Offenders § 548.17 Work assignments. When the...

  12. 28 CFR 548.17 - Work assignments.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Work assignments. 548.17 Section 548.17 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT RELIGIOUS PROGRAMS Religious Beliefs and Practices of Committed Offenders § 548.17 Work assignments. When the...

  13. 28 CFR 548.17 - Work assignments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Work assignments. 548.17 Section 548.17 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT RELIGIOUS PROGRAMS Religious Beliefs and Practices of Committed Offenders § 548.17 Work assignments. When the...

  14. The reference frame of figure-ground assignment.

    PubMed

    Vecera, Shaun P

    2004-10-01

    Figure-ground assignment involves determining which visual regions are foreground figures and which are backgrounds. Although figure-ground processes provide important inputs to high-level vision, little is known about the reference frame in which the figure's features and parts are defined. Computational approaches have suggested a retinally based, viewer-centered reference frame for figure-ground assignment, but figural assignment could also be computed on the basis of environmental regularities in an environmental reference frame. The present research used a newly discovered cue, lower region, to examine the reference frame of figure-ground assignment. Possible reference frames were misaligned by changing the orientation of viewers by having them tilt their heads (Experiments 1 and 2) or turn them upside down (Experiment 3). The results of these experiments indicated that figure-ground perception followed the orientation of the viewer, suggesting a viewer-centered reference frame for figure-ground assignment.

  15. My Favorite Assignment.

    ERIC Educational Resources Information Center

    Hebert, Margaret; And Others

    1991-01-01

    Contains seven brief articles which offer assignments designed to help students perform job searches, write job application letters, answer difficult questions, write letters of resignation, alleviate fears of public speaking, use the interview effectively in the business communication, and develop listening skills. (PRA)

  16. Global Optimization of Emergency Evacuation Assignments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Han, Lee; Yuan, Fang; Chin, Shih-Miao

    2006-01-01

    Conventional emergency evacuation plans often assign evacuees to fixed routes or destinations based mainly on geographic proximity. Such approaches can be inefficient if the roads are congested, blocked, or otherwise dangerous because of the emergency. By not constraining evacuees to prespecified destinations, a one-destination evacuation approach provides flexibility in the optimization process. We present a framework for the simultaneous optimization of evacuation-traffic distribution and assignment. Based on the one-destination evacuation concept, we can obtain the optimal destination and route assignment by solving a one-destination traffic-assignment problem on a modified network representation. In a county-wide, large-scale evacuation case study, the one-destinationmore » model yields substantial improvement over the conventional approach, with the overall evacuation time reduced by more than 60 percent. More importantly, emergency planners can easily implement this framework by instructing evacuees to go to destinations that the one-destination optimization process selects.« less

  17. 76 FR 46767 - Privacy Act of 1974; System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... Army, Navy, Marine Corps, Air Force, civilians employed by the U.S. Government; and approved foreign military personnel when assigned to exchange duty in the U.S. and enrolled in a resident course or Web... subject to the Privacy Act of 1974 (5 U.S.C. 552a), as amended. DATES: This proposed action would be...

  18. CC chemokine ligand 2 and CXC chemokine ligand 8 as neutrophil chemoattractant factors in canine idiopathic polyarthritis.

    PubMed

    Murakami, Kohei; Maeda, Shingo; Yonezawa, Tomohiro; Matsuki, Naoaki

    2016-12-01

    Canine idiopathic polyarthritis (IPA) is characterized by increased numbers of polymorphonuclear leukocytes (PMNs) in the synovial fluid (SF). In humans, CC chemokine ligand 2 (CCL2) and CXC chemokine ligand 8 (CXCL8) recruit monocytes and neutrophils, respectively, and are involved in various inflammatory disorders. The aim of this study was to assess the roles of these chemokines in driving PMNs infiltration into the joints of dogs with IPA. SF samples were collected from dogs with IPA (n=19) and healthy controls (n=8), and the concentrations of SF CCL2 and CXCL8 were determined by ELISA. Dogs with IPA had significantly higher concentrations of CCL2 (3316±2452pg/ml, mean±SD) and CXCL8 (3668±3879pg/ml) compared with the healthy controls (235±45pg/ml and <15.6pg/ml, respectively). Then, an in vitro chemotaxis assay was performed using a modified Boyden chamber (pore size: 3μm). SF from IPA dogs had a chemoattractant activity for PMNs that purified from the peripheral blood of a healthy dog. We subsequently found that combination treatment with MK-0812 (an antagonist of CCL2 receptor) and repertaxin (an antagonist of CXCL8 receptors) significantly inhibited the migration of PMNs to SF from IPA dogs. Thus, expression of the CCL2 receptor (chemokine (CC motif) receptor 2 (CCR2)) was examined using polymerase chain reaction and immunocytochemistry. Canine peripheral blood PMNs exhibited significantly higher CCR2 mRNA expression levels than those in monocytes. In addition, we observed strong CCR2 expression on PMNs obtained from healthy controls and IPA dogs, although mononuclear cells did not express CCR2. Taken together, the data suggest that CCL2 acts as a canine PMNs chemotactic factor as well as CXCL8 and both CCL2 and CXCL8 facilitate the infiltration of PMNs into the joints of dogs with IPA. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. 31 CFR 306.56 - Assignment of securities registered in the names of or assigned to two or more persons.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... assigned to two or more persons in the alternative, for example, “John B. Smith or Mrs. Mary J. Smith” or “John B. Smith or Mrs. Mary J. Smith or the survivor,” may be assigned by one of them at maturity or... the names of or assigned to two or more persons jointly, for example, “John B. Smith and Mrs. Mary J...

  20. 46 CFR 387.5 - Surplus property assignment recommendation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Surplus property assignment recommendation. 387.5 Section 387.5 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MISCELLANEOUS UTILIZATION AND... property assignment recommendation. Before any assignment recommendation is submitted to the Disposal...

  1. 46 CFR 387.5 - Surplus property assignment recommendation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Surplus property assignment recommendation. 387.5 Section 387.5 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MISCELLANEOUS UTILIZATION AND... property assignment recommendation. Before any assignment recommendation is submitted to the Disposal...

  2. 37 CFR 501.3 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Intergovernmental Personnel Act (IPA), 5 U.S.C. 1304 and 3371-3376, or a part-time consultant or part-time employee... by the Secretary. (d) The term invention, as used in this part, means any art or process, machine...

  3. Commercialization of Advanced Communications Technology Satellite (ACTS) technology

    NASA Astrophysics Data System (ADS)

    Plecity, Mark S.; Strickler, Walter M.; Bauer, Robert A.

    1996-03-01

    In an on-going effort to maintain United States leadership in communication satellite technology, the National Aeronautics and Space Administration (NASA), led the development of the Advanced Communications Technology Satellite (ACTS). NASA's ACTS program provides industry, academia, and government agencies the opportunity to perform both technology and telecommunication service experiments with a leading-edge communication satellite system. Over 80 organizations are using ACTS as a multi server test bed to establish communication technologies and services of the future. ACTS was designed to provide demand assigned multiple access (DAMA) digital communications with a minimum switchable circuit bandwidth of 64 Kbps, and a maximum channel bandwidth of 900 MHZ. It can, therefore, provide service to thin routes as well as connect fiber backbones in supercomputer networks, across oceans, or restore full communications in the event of national or manmade disaster. Service can also be provided to terrestrial and airborne mobile users. Commercial applications of ACTS technologies include: telemedicine; distance education; Department of Defense operations; mobile communications, aeronautical applications, terrestrial applications, and disaster recovery. This paper briefly describes the ACTS system and the enabling technologies employed by ACTS including Ka-band hopping spot beams, on-board routing and switching, and rain fade compensation. When used in conjunction with a time division multiple access (TDMA) architecture, these technologies provide a higher capacity, lower cost satellite system. Furthermore, examples of completed user experiments, future experiments, and plans of organizations to commercialize ACTS technology in their own future offerings will be discussed.

  4. Herpesvirus papio contains a plasmid origin of replication that acts in cis interspecies with an Epstein-Barr virus trans-acting function.

    PubMed Central

    Pesano, R L; Pagano, J S

    1986-01-01

    Herpesvirus papio (HVP) and Epstein-Barr virus (EBV) are closely related biologically and biochemically; lymphoblastoid cells infected with either virus contain episomal viral DNA. The putative origin of replication for EBV plasmids (oriP) has been assigned to a 1,790-base-pair fragment (cis) in the short unique region of the genome which requires a viral function supplied in trans from elsewhere in the genome (J. Yates, N. Warren, D. Reisman, and B. Sugden, Proc. Natl. Acad. Sci. USA 81:3806-3810, 1984). We report here the identification of the putative origin of replication (cis) in HVP; we assigned it to the HVP EcoRI K fragment. The results indicate that the HVP replication process requires both a cis and a trans-acting function, analogous to that found in EBV. Images PMID:3023667

  5. Homework assignments in couple and family therapy.

    PubMed

    Dattilio, Frank M

    2002-05-01

    Homework has been cited as an integral part of a number of theoretical orientations and therapy formats; unfortunately, very little has been written about its use with couples and families. This is despite the fact that many couple and family therapists espouse the use of homework or out-of-session assignments in order to help the effects of therapy jell. This article reviews some of the empirical literature on homework assignments and their effectiveness in the domain of therapy for families and couples. It also highlights the effectiveness of and the need for out-of-session assignments in treatment. A case illustration is used to demonstrate how homework assignments may be used as a significant change agent in couple and family treatment. Copyright 2002 Wiley Periodicals, Inc.

  6. Writing Assignments that Promote Active Learning

    NASA Astrophysics Data System (ADS)

    Narayanan, M.

    2014-12-01

    Encourage students to write a detailed, analytical report correlating classroom discussions to an important historical event or a current event. Motivate students interview an expert from industry on a topic that was discussed in class. Ask the students to submit a report with supporting sketches, drawings, circuit diagrams and graphs. Propose that the students generate a complete a set of reading responses pertaining to an assigned topic. Require each student to bring in one comment or one question about an assigned reading. The assignment should be a recent publication in an appropriate journal. Have the students conduct a web search on an assigned topic. Ask them to generate a set of ideas that can relate to classroom discussions. Provide the students with a study guide. The study guide should provide about 10 or 15 short topics. Quiz the students on one or two of the topics. Encourage the students to design or develop some creative real-world examples based on a chapter discussed or a topic of interest. Require that students originate, develop, support and defend a viewpoint using a specifically assigned material. Make the students practice using or utilizing a set of new technical terms they have encountered in an assigned chapter. Have students develop original examples explaining the different terms. Ask the students to select one important terminology from the previous classroom discussions. Encourage the students to explain why they selected that particular word. Ask them to talk about the importance of the terminology from the point of view of their educational objectives and future career. Angelo, T. A. (1991). Ten easy pieces: Assessing higher learning in four dimensions. In T. A. Angelo (Ed.), Classroom research: Early lessons from success (pp. 17-31). New Directions for Teaching and Learning, No. 46. San Francisco: Jossey-Bass.

  7. 47 CFR 78.18 - Frequency assignments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Frequency assignments. 78.18 Section 78.18... SERVICE Applications and Licenses § 78.18 Frequency assignments. (a) The Cable Television Relay Service is... Relay Service stations operating on frequencies in the sub-bands 18.3-18.58 GHz and 19.26-19.3 GHz that...

  8. 47 CFR 78.18 - Frequency assignments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Frequency assignments. 78.18 Section 78.18... SERVICE Applications and Licenses § 78.18 Frequency assignments. (a) The Cable Television Relay Service is... Relay Service stations operating on frequencies in the sub-bands 18.3-18.58 GHz and 19.26-19.3 GHz that...

  9. 47 CFR 78.18 - Frequency assignments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 4 2014-10-01 2014-10-01 false Frequency assignments. 78.18 Section 78.18... SERVICE Applications and Licenses § 78.18 Frequency assignments. (a) The Cable Television Relay Service is... Relay Service stations operating on frequencies in the sub-bands 18.3-18.58 GHz and 19.26-19.3 GHz that...

  10. 47 CFR 78.18 - Frequency assignments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false Frequency assignments. 78.18 Section 78.18... SERVICE Applications and Licenses § 78.18 Frequency assignments. (a) The Cable Television Relay Service is... Relay Service stations operating on frequencies in the sub-bands 18.3-18.58 GHz and 19.26-19.3 GHz that...

  11. 47 CFR 78.18 - Frequency assignments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 4 2013-10-01 2013-10-01 false Frequency assignments. 78.18 Section 78.18... SERVICE Applications and Licenses § 78.18 Frequency assignments. (a) The Cable Television Relay Service is... Relay Service stations operating on frequencies in the sub-bands 18.3-18.58 GHz and 19.26-19.3 GHz that...

  12. 47 CFR 74.702 - Channel assignments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., AUXILIARY, SPECIAL BROADCAST AND OTHER PROGRAM DISTRIBUTIONAL SERVICES Low Power TV, TV Translator, and TV Booster Stations § 74.702 Channel assignments. (a) An applicant for a new low power TV or TV translator... standard VHF Channels (2 to 13 inclusive) may be assigned to a VHF low power TV or TV translator station...

  13. 32 CFR 241.6 - Length of assignments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Components and private sector organizations. (b) No assignment may commence after September 30, 2013, unless an individual began an assignment by September 30, 2013. This extension may be granted in 3-month...

  14. 28 CFR 301.103 - Inmate work assignments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... designates work assignments, or whoever makes work assignments, shall review appropriate medical records... compatible with the inmate's physical ability or condition. [55 FR 9296, Mar. 12, 1990, as amended at 59 FR...

  15. 4 CFR 3.1 - Appointment, promotion, and assignment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 4 Accounts 1 2010-01-01 2010-01-01 false Appointment, promotion, and assignment. 3.1 Section 3.1 Accounts GOVERNMENT ACCOUNTABILITY OFFICE PERSONNEL SYSTEM EMPLOYMENT § 3.1 Appointment, promotion, and assignment. Employees of GAO shall be appointed, promoted and assigned solely on the basis of merit and...

  16. 7 CFR 400.305 - Assignment of Nonstandard Classifications.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... tables for the county. (b) Nonstandard classification assignment will be made each year, for the year... 7 Agriculture 6 2011-01-01 2011-01-01 false Assignment of Nonstandard Classifications. 400.305... Underwriting Classification System Regulations for the 1991 and Succeeding Crop Years § 400.305 Assignment of...

  17. 7 CFR 400.305 - Assignment of Nonstandard Classifications.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... tables for the county. (b) Nonstandard classification assignment will be made each year, for the year... 7 Agriculture 6 2010-01-01 2010-01-01 false Assignment of Nonstandard Classifications. 400.305... Underwriting Classification System Regulations for the 1991 and Succeeding Crop Years § 400.305 Assignment of...

  18. 50 CFR Table 47a to Part 679 - Percent of the AFA Catcher/Processor Sector's Pollock Allocation, Numbers of Chinook Salmon Used...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Percent of the AFA Catcher/Processor Sector's Pollock Allocation, Numbers of Chinook Salmon Used To Calculate the Opt-out Allocation and Annual Threshold Amount, and Percent Used To Calculate IPA Minimum Participation Assigned to Each Catcher/Processor Under § 679.21(f) 47a Table 47a to...

  19. 50 CFR Table 47b to Part 679 - Percent of the AFA Mothership Sector's Pollock Allocation, Numbers of Chinook Salmon Used To...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Percent of the AFA Mothership Sector's Pollock Allocation, Numbers of Chinook Salmon Used To Calculate the Opt-Out Allocation and Annual Threshold Amount, and Percent Used To Calculate IPA Minimum Participation Assigned to Each Mothership Under § 679.21(f) 47b Table 47b to Part 679...

  20. 50 CFR Table 47d to Part 679 - Percent of the CDQ Program's Pollock Allocation, Numbers of Chinook Salmon Used To Calculate the...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Percent of the CDQ Program's Pollock Allocation, Numbers of Chinook Salmon Used To Calculate the Opt-Out Allocation and Annual Threshold Amount, and Percent Used To Calculate IPA Minimum Participation Assigned to Each CDQ Group Under § 679.21(f) 47d Table 47d to Part 679 Wildlife and...

  1. 50 CFR Table 47b to Part 679 - Percent of the AFA Mothership Sector's Pollock Allocation, Numbers of Chinook Salmon Used To...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 13 2012-10-01 2012-10-01 false Percent of the AFA Mothership Sector's Pollock Allocation, Numbers of Chinook Salmon Used To Calculate the Opt-Out Allocation and Annual Threshold Amount, and Percent Used To Calculate IPA Minimum Participation Assigned to Each Mothership Under § 679.21(f) 47b Table 47b to Part 679...

  2. Detecting Plagiarism in MS Access Assignments

    ERIC Educational Resources Information Center

    Singh, Anil

    2013-01-01

    Assurance of individual effort from students in computer-based assignments is a challenge. Due to digitization, students can easily use a copy of their friend's work and submit it as their own. Plagiarism in assignments puts students who cheat at par with those who work honestly and this compromises the learning evaluation process. Using a…

  3. Absolute Points for Multiple Assignment Problems

    ERIC Educational Resources Information Center

    Adlakha, V.; Kowalski, K.

    2006-01-01

    An algorithm is presented to solve multiple assignment problems in which a cost is incurred only when an assignment is made at a given cell. The proposed method recursively searches for single/group absolute points to identify cells that must be loaded in any optimal solution. Unlike other methods, the first solution is the optimal solution. The…

  4. 7 CFR 1.77 - Assignment of priorities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Television Films § 1.77 Assignment of priorities. (a) Authority. (1) The Director of Information or his designee will make assignment of priorities for the U.S. Department of Agriculture for a television film...

  5. 7 CFR 1.77 - Assignment of priorities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Television Films § 1.77 Assignment of priorities. (a) Authority. (1) The Director of Information or his designee will make assignment of priorities for the U.S. Department of Agriculture for a television film...

  6. 7 CFR 1.77 - Assignment of priorities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Television Films § 1.77 Assignment of priorities. (a) Authority. (1) The Director of Information or his designee will make assignment of priorities for the U.S. Department of Agriculture for a television film...

  7. 7 CFR 1.77 - Assignment of priorities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Television Films § 1.77 Assignment of priorities. (a) Authority. (1) The Director of Information or his designee will make assignment of priorities for the U.S. Department of Agriculture for a television film...

  8. Assigning historic responsibility for extreme weather events

    NASA Astrophysics Data System (ADS)

    Otto, Friederike E. L.; Skeie, Ragnhild B.; Fuglestvedt, Jan S.; Berntsen, Terje; Allen, Myles R.

    2017-11-01

    Recent scientific advances make it possible to assign extreme events to human-induced climate change and historical emissions. These developments allow losses and damage associated with such events to be assigned country-level responsibility.

  9. 7 CFR 1.77 - Assignment of priorities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Television Films § 1.77 Assignment of priorities. (a) Authority. (1) The Director of Information or his designee will make assignment of priorities for the U.S. Department of Agriculture for a television film...

  10. Quantum probability assignment limited by relativistic causality.

    PubMed

    Han, Yeong Deok; Choi, Taeseung

    2016-03-14

    Quantum theory has nonlocal correlations, which bothered Einstein, but found to satisfy relativistic causality. Correlation for a shared quantum state manifests itself, in the standard quantum framework, by joint probability distributions that can be obtained by applying state reduction and probability assignment that is called Born rule. Quantum correlations, which show nonlocality when the shared state has an entanglement, can be changed if we apply different probability assignment rule. As a result, the amount of nonlocality in quantum correlation will be changed. The issue is whether the change of the rule of quantum probability assignment breaks relativistic causality. We have shown that Born rule on quantum measurement is derived by requiring relativistic causality condition. This shows how the relativistic causality limits the upper bound of quantum nonlocality through quantum probability assignment.

  11. Mathematics Textbooks and the Teaching of Assigned Writing.

    ERIC Educational Resources Information Center

    Donlan, Dan

    This paper initially presents the results of several studies concerning what kind of writing mathematics teachers assign and what kind of writing mathematics textbooks assign. By far, report-research was the most popular type of writing assigned in the surveyed textbooks. The types of reports students were asked to write include biography,…

  12. 7 CFR 37.16 - OMB assigned numbers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 2 2014-01-01 2014-01-01 false OMB assigned numbers. 37.16 Section 37.16 Agriculture... ASSESS ORGANIC CERTIFYING AGENCIES § 37.16 OMB assigned numbers. The information collection and... Control Number 0581-0183. ...

  13. Flexible taxonomic assignment of ambiguous sequencing reads

    PubMed Central

    2011-01-01

    Background To characterize the diversity of bacterial populations in metagenomic studies, sequencing reads need to be accurately assigned to taxonomic units in a given reference taxonomy. Reads that cannot be reliably assigned to a unique leaf in the taxonomy (ambiguous reads) are typically assigned to the lowest common ancestor of the set of species that match it. This introduces a potentially severe error in the estimation of bacteria present in the sample due to false positives, since all species in the subtree rooted at the ancestor are implicitly assigned to the read even though many of them may not match it. Results We present a method that maps each read to a node in the taxonomy that minimizes a penalty score while balancing the relevance of precision and recall in the assignment through a parameter q. This mapping can be obtained in time linear in the number of matching sequences, because LCA queries to the reference taxonomy take constant time. When applied to six different metagenomic datasets, our algorithm produces different taxonomic distributions depending on whether coverage or precision is maximized. Including information on the quality of the reads reduces the number of unassigned reads but increases the number of ambiguous reads, stressing the relevance of our method. Finally, two measures of performance are described and results with a set of artificially generated datasets are discussed. Conclusions The assignment strategy of sequencing reads introduced in this paper is a versatile and a quick method to study bacterial communities. The bacterial composition of the analyzed samples can vary significantly depending on how ambiguous reads are assigned depending on the value of the q parameter. Validation of our results in an artificial dataset confirm that a combination of values of q produces the most accurate results. PMID:21211059

  14. An Algorithm for Protein Helix Assignment Using Helix Geometry

    PubMed Central

    Cao, Chen; Xu, Shutan; Wang, Lincong

    2015-01-01

    Helices are one of the most common and were among the earliest recognized secondary structure elements in proteins. The assignment of helices in a protein underlies the analysis of its structure and function. Though the mathematical expression for a helical curve is simple, no previous assignment programs have used a genuine helical curve as a model for helix assignment. In this paper we present a two-step assignment algorithm. The first step searches for a series of bona fide helical curves each one best fits the coordinates of four successive backbone Cα atoms. The second step uses the best fit helical curves as input to make helix assignment. The application to the protein structures in the PDB (protein data bank) proves that the algorithm is able to assign accurately not only regular α-helix but also 310 and π helices as well as their left-handed versions. One salient feature of the algorithm is that the assigned helices are structurally more uniform than those by the previous programs. The structural uniformity should be useful for protein structure classification and prediction while the accurate assignment of a helix to a particular type underlies structure-function relationship in proteins. PMID:26132394

  15. Effects of Controlled Breathing, With or Without Aromatherapy, in the Treatment of Postoperative Nausea.

    PubMed

    Cronin, Sherill Nones; Odom-Forren, Jan; Roberts, Holli; Thomas, Melissa; Williams, Sandy; Wright, Margaret Imelda

    2015-10-01

    The purpose of this study was to compare the effectiveness of controlled breathing (CB), with and without aromatherapy (isopropyl alcohol [IPA]), in the treatment of postoperative nausea (PON) in adult females undergoing elective outpatient laparoscopic procedures. A prospective randomized two-group quasi-experimental design was used. A convenience sample was used. Patients were consented and assigned to either a control (CB) or treatment (IPA) group. Symptomatic patients rated nausea severity before and at 2 and 5 minutes after receiving either CB or CB with IPA. Complete data for one episode of nausea were obtained on 82 patients (41 in each group). Results showed that although nausea severity decreased significantly over time, there was no significant difference in PON treatment effectiveness between the two groups, nor was there a difference in requests for rescue medications. Patients who experience PON should be encouraged to take slow deep breaths as an initial response to symptoms. This approach has no side effects or costs and could also aid the patient to self-manage symptoms after discharge. Copyright © 2015 American Society of PeriAnesthesia Nurses. Published by Elsevier Inc. All rights reserved.

  16. 48 CFR 642.602 - Assignment and location.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Assignment and location. 642.602 Section 642.602 Federal Acquisition Regulations System DEPARTMENT OF STATE CONTRACT MANAGEMENT CONTRACT ADMINISTRATION AND AUDIT SERVICES Corporate Administration Contracting Officer 642.602 Assignment...

  17. 47 CFR 74.402 - Frequency assignment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... two of the following 6.25 kHz segments may be stacked to form a channel which may be assigned for use... paragraph (e)(9) of this section. (b) Up to four of the following 7.5 kHz VHF segments and up to eight of the following 6.25 kHz UHF segments may be stacked to form a channel which may be assigned for use by...

  18. 47 CFR 74.402 - Frequency assignment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... two of the following 6.25 kHz segments may be stacked to form a channel which may be assigned for use... paragraph (e)(9) of this section. (b) Up to four of the following 7.5 kHz VHF segments and up to eight of the following 6.25 kHz UHF segments may be stacked to form a channel which may be assigned for use by...

  19. 47 CFR 74.402 - Frequency assignment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... two of the following 6.25 kHz segments may be stacked to form a channel which may be assigned for use... paragraph (e)(9) of this section. (b) Up to four of the following 7.5 kHz VHF segments and up to eight of the following 6.25 kHz UHF segments may be stacked to form a channel which may be assigned for use by...

  20. 47 CFR 74.402 - Frequency assignment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... two of the following 6.25 kHz segments may be stacked to form a channel which may be assigned for use... paragraph (e)(9) of this section. (b) Up to four of the following 7.5 kHz VHF segments and up to eight of the following 6.25 kHz UHF segments may be stacked to form a channel which may be assigned for use by...

  1. 47 CFR 215.2 - Assignment of responsibilities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 5 2013-10-01 2013-10-01 false Assignment of responsibilities. 215.2 Section 215.2 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL FEDERAL GOVERNMENT FOCAL POINT FOR ELECTROMAGNETIC PULSE (EMP) INFORMATION § 215.2 Assignment of responsibilities...

  2. 47 CFR 215.2 - Assignment of responsibilities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 5 2012-10-01 2012-10-01 false Assignment of responsibilities. 215.2 Section 215.2 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL FEDERAL GOVERNMENT FOCAL POINT FOR ELECTROMAGNETIC PULSE (EMP) INFORMATION § 215.2 Assignment of responsibilities...

  3. 47 CFR 215.2 - Assignment of responsibilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Assignment of responsibilities. 215.2 Section 215.2 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL FEDERAL GOVERNMENT FOCAL POINT FOR ELECTROMAGNETIC PULSE (EMP) INFORMATION § 215.2 Assignment of responsibilities...

  4. 47 CFR 215.2 - Assignment of responsibilities.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 47 Telecommunication 5 2014-10-01 2014-10-01 false Assignment of responsibilities. 215.2 Section 215.2 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL FEDERAL GOVERNMENT FOCAL POINT FOR ELECTROMAGNETIC PULSE (EMP) INFORMATION § 215.2 Assignment of responsibilities...

  5. 47 CFR 215.2 - Assignment of responsibilities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Assignment of responsibilities. 215.2 Section 215.2 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL FEDERAL GOVERNMENT FOCAL POINT FOR ELECTROMAGNETIC PULSE (EMP) INFORMATION § 215.2 Assignment of responsibilities...

  6. Stress Assignment in Reading Italian Polysyllabic Pseudowords

    ERIC Educational Resources Information Center

    Sulpizio, Simone; Arduino, Lisa S.; Paizi, Despina; Burani, Cristina

    2013-01-01

    In 4 naming experiments we investigated how Italian readers assign stress to pseudowords. We assessed whether participants assign stress following distributional information such as stress neighborhood (the proportion and number of existent words sharing orthographic ending and stress pattern) and whether such distributional information affects…

  7. Assigning breed origin to alleles in crossbred animals.

    PubMed

    Vandenplas, Jérémie; Calus, Mario P L; Sevillano, Claudia A; Windig, Jack J; Bastiaansen, John W M

    2016-08-22

    For some species, animal production systems are based on the use of crossbreeding to take advantage of the increased performance of crossbred compared to purebred animals. Effects of single nucleotide polymorphisms (SNPs) may differ between purebred and crossbred animals for several reasons: (1) differences in linkage disequilibrium between SNP alleles and a quantitative trait locus; (2) differences in genetic backgrounds (e.g., dominance and epistatic interactions); and (3) differences in environmental conditions, which result in genotype-by-environment interactions. Thus, SNP effects may be breed-specific, which has led to the development of genomic evaluations for crossbred performance that take such effects into account. However, to estimate breed-specific effects, it is necessary to know breed origin of alleles in crossbred animals. Therefore, our aim was to develop an approach for assigning breed origin to alleles of crossbred animals (termed BOA) without information on pedigree and to study its accuracy by considering various factors, including distance between breeds. The BOA approach consists of: (1) phasing genotypes of purebred and crossbred animals; (2) assigning breed origin to phased haplotypes; and (3) assigning breed origin to alleles of crossbred animals based on a library of assigned haplotypes, the breed composition of crossbred animals, and their SNP genotypes. The accuracy of allele assignments was determined for simulated datasets that include crosses between closely-related, distantly-related and unrelated breeds. Across these scenarios, the percentage of alleles of a crossbred animal that were correctly assigned to their breed origin was greater than 90 %, and increased with increasing distance between breeds, while the percentage of incorrectly assigned alleles was always less than 2 %. For the remaining alleles, i.e. 0 to 10 % of all alleles of a crossbred animal, breed origin could not be assigned. The BOA approach accurately assigns

  8. Unifying Temporal and Structural Credit Assignment Problems

    NASA Technical Reports Server (NTRS)

    Agogino, Adrian K.; Tumer, Kagan

    2004-01-01

    Single-agent reinforcement learners in time-extended domains and multi-agent systems share a common dilemma known as the credit assignment problem. Multi-agent systems have the structural credit assignment problem of determining the contributions of a particular agent to a common task. Instead, time-extended single-agent systems have the temporal credit assignment problem of determining the contribution of a particular action to the quality of the full sequence of actions. Traditionally these two problems are considered different and are handled in separate ways. In this article we show how these two forms of the credit assignment problem are equivalent. In this unified frame-work, a single-agent Markov decision process can be broken down into a single-time-step multi-agent process. Furthermore we show that Monte-Carlo estimation or Q-learning (depending on whether the values of resulting actions in the episode are known at the time of learning) are equivalent to different agent utility functions in a multi-agent system. This equivalence shows how an often neglected issue in multi-agent systems is equivalent to a well-known deficiency in multi-time-step learning and lays the basis for solving time-extended multi-agent problems, where both credit assignment problems are present.

  9. A new algorithm for reliable and general NMR resonance assignment.

    PubMed

    Schmidt, Elena; Güntert, Peter

    2012-08-01

    The new FLYA automated resonance assignment algorithm determines NMR chemical shift assignments on the basis of peak lists from any combination of multidimensional through-bond or through-space NMR experiments for proteins. Backbone and side-chain assignments can be determined. All experimental data are used simultaneously, thereby exploiting optimally the redundancy present in the input peak lists and circumventing potential pitfalls of assignment strategies in which results obtained in a given step remain fixed input data for subsequent steps. Instead of prescribing a specific assignment strategy, the FLYA resonance assignment algorithm requires only experimental peak lists and the primary structure of the protein, from which the peaks expected in a given spectrum can be generated by applying a set of rules, defined in a straightforward way by specifying through-bond or through-space magnetization transfer pathways. The algorithm determines the resonance assignment by finding an optimal mapping between the set of expected peaks that are assigned by definition but have unknown positions and the set of measured peaks in the input peak lists that are initially unassigned but have a known position in the spectrum. Using peak lists obtained by purely automated peak picking from the experimental spectra of three proteins, FLYA assigned correctly 96-99% of the backbone and 90-91% of all resonances that could be assigned manually. Systematic studies quantified the impact of various factors on the assignment accuracy, namely the extent of missing real peaks and the amount of additional artifact peaks in the input peak lists, as well as the accuracy of the peak positions. Comparing the resonance assignments from FLYA with those obtained from two other existing algorithms showed that using identical experimental input data these other algorithms yielded significantly (40-142%) more erroneous assignments than FLYA. The FLYA resonance assignment algorithm thus has the

  10. Integer Linear Programming for Constrained Multi-Aspect Committee Review Assignment

    PubMed Central

    Karimzadehgan, Maryam; Zhai, ChengXiang

    2011-01-01

    Automatic review assignment can significantly improve the productivity of many people such as conference organizers, journal editors and grant administrators. A general setup of the review assignment problem involves assigning a set of reviewers on a committee to a set of documents to be reviewed under the constraint of review quota so that the reviewers assigned to a document can collectively cover multiple topic aspects of the document. No previous work has addressed such a setup of committee review assignments while also considering matching multiple aspects of topics and expertise. In this paper, we tackle the problem of committee review assignment with multi-aspect expertise matching by casting it as an integer linear programming problem. The proposed algorithm can naturally accommodate any probabilistic or deterministic method for modeling multiple aspects to automate committee review assignments. Evaluation using a multi-aspect review assignment test set constructed using ACM SIGIR publications shows that the proposed algorithm is effective and efficient for committee review assignments based on multi-aspect expertise matching. PMID:22711970

  11. 7 CFR 762.160 - Assignment of guarantee.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Assignment of guarantee. 762.160 Section 762.160 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS GUARANTEED FARM LOANS § 762.160 Assignment of guarantee. (a) The following...

  12. 28 CFR 524.72 - CIM assignment categories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... groups (e.g., prison gangs), which have a history of disrupting operations and security in either state... assignment categories. CIM cases are classified according to the following assignments: (a) Witness Security... safety of these individuals. There are two types of Witness Security cases: Department of Justice...

  13. 36 CFR 292.22 - Land category assignments.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the following four land categories: (i) Farm/forest/grazing land. (ii) Mining land. (iii) Residential.... Lands assigned to the Commercial, Residential, or Mining category may be reclassified as farm/forest... 36 Parks, Forests, and Public Property 2 2013-07-01 2013-07-01 false Land category assignments...

  14. 36 CFR 292.22 - Land category assignments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the following four land categories: (i) Farm/forest/grazing land. (ii) Mining land. (iii) Residential.... Lands assigned to the Commercial, Residential, or Mining category may be reclassified as farm/forest... 36 Parks, Forests, and Public Property 2 2011-07-01 2011-07-01 false Land category assignments...

  15. 36 CFR 292.22 - Land category assignments.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the following four land categories: (i) Farm/forest/grazing land. (ii) Mining land. (iii) Residential.... Lands assigned to the Commercial, Residential, or Mining category may be reclassified as farm/forest... 36 Parks, Forests, and Public Property 2 2012-07-01 2012-07-01 false Land category assignments...

  16. 36 CFR 292.22 - Land category assignments.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the following four land categories: (i) Farm/forest/grazing land. (ii) Mining land. (iii) Residential.... Lands assigned to the Commercial, Residential, or Mining category may be reclassified as farm/forest... 36 Parks, Forests, and Public Property 2 2014-07-01 2014-07-01 false Land category assignments...

  17. Maximizing Completion and Comprehension of Reading Assignments

    ERIC Educational Resources Information Center

    Owen, Leanne R.

    2017-01-01

    The author presents self-report data from students in three upper-level undergraduate courses to illustrate the comparative effectiveness of different out-of-class assessment approaches in promoting completion and comprehension of reading assignments. Students reported agreeing or strongly agreeing that all three assignments motivated them to…

  18. Continuous Improvement of Team Assignments: Using a Web-based Tool and the Plan-Do-Check-Act Cycle in Design and Redesign

    ERIC Educational Resources Information Center

    Morgan, Shona D.; Stewart, Alice C.

    2017-01-01

    The purpose of this brief is twofold. First, it describes a useful template for business instructors to improve teamwork assignment design and efficacy; and second, it provides an example of how to use data collected and analyzed from a Web-based tool, Comprehensive Assessment of Team Member Effectiveness (CATME). Though CATME has been the subject…

  19. One of My Favorite Assignments: Automated Teller Machine Simulation.

    ERIC Educational Resources Information Center

    Oberman, Paul S.

    2001-01-01

    Describes an assignment for an introductory computer science class that requires the student to write a software program that simulates an automated teller machine. Highlights include an algorithm for the assignment; sample file contents; language features used; assignment variations; and discussion points. (LRW)

  20. 7 CFR 1900.5 - Assignment of cases.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Assignment of cases. 1900.5 Section 1900.5 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS... REGULATIONS GENERAL Delegations of Authority § 1900.5 Assignment of cases. The State Director may, in writing...

  1. 47 CFR 74.786 - Digital channel assignments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Translator, and TV Booster Stations § 74.786 Digital channel assignments. (a) An applicant for a new low power television or television translator digital station or for changes in the facilities of an... VHF digital low power television or television translator station. Channels 5 and 6 assigned in Alaska...

  2. 7 CFR 1210.540 - OMB assigned numbers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false OMB assigned numbers. 1210.540 Section 1210.540 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... Management and Budget (OMB) under the provisions of 44 U.S.C. chapter 35 and have been assigned OMB Control...

  3. Impact of an All-or-Nothing Assignment Requirement under Medicare

    PubMed Central

    Mitchell, Janet B.; Cromwell, Jerry

    1983-01-01

    In an effort to raise assignment rates, some policymakers have considered dropping Medicare's case-by-case assignment option. Physicians would have to decide whether to accept all of their patients on assignment, or none of them. In a 1976 national survey, over two-thirds of the physicians stated they would take none of their patients on assignment if forced to choose. Simulation analysis showed that in that event, assignment rates nationwide would fall almost 10 percent. The mean supply of assigned visits would actually increase 11 percent for general practitioners, while decreasing 12-25 percent for general surgeons, internists, and obstetricians/gynecologists. PMID:10310000

  4. Testing the Effectiveness of Online Assignments in Theory of Finance

    ERIC Educational Resources Information Center

    Batu, Michael; Bower, Nancy; Lun, Esmond; Sadanand, Asha

    2018-01-01

    The authors investigated the effectiveness of online versus paper assignments using final examination scores in three cohorts of theory of finance. In particular, two cohorts were exposed to online assignments while another cohort was exposed to traditional assignments. The central result is that exposure to online assignments robustly leads to…

  5. Assignment Choice: Do Students Choose Briefer Assignments or Finishing What They Started?

    ERIC Educational Resources Information Center

    Hawthorn-Embree, Meredith L.; Skinner, Christopher H.; Parkhurst, John; O'Neil, Michael; Conley, Elisha

    2010-01-01

    Academic skill development requires engagement in effortful academic behaviors. Although students may be more likely to choose to engage in behaviors that require less effort, they also may be motivated to complete assignments that they have already begun. Seventh-grade students (N = 88) began a mathematics computation worksheet, but were stopped…

  6. 24 CFR 241.895 - Assignment of insured loans.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... AUTHORITIES SUPPLEMENTARY FINANCING FOR INSURED PROJECT MORTGAGES Contract Rights and Obligations-Multifamily Projects Without a HUD-Insured or HUD-Held Mortgage Assignments § 241.895 Assignment of insured loans. (a...

  7. Gain weighted eigenspace assignment

    NASA Technical Reports Server (NTRS)

    Davidson, John B.; Andrisani, Dominick, II

    1994-01-01

    This report presents the development of the gain weighted eigenspace assignment methodology. This provides a designer with a systematic methodology for trading off eigenvector placement versus gain magnitudes, while still maintaining desired closed-loop eigenvalue locations. This is accomplished by forming a cost function composed of a scalar measure of error between desired and achievable eigenvectors and a scalar measure of gain magnitude, determining analytical expressions for the gradients, and solving for the optimal solution by numerical iteration. For this development the scalar measure of gain magnitude is chosen to be a weighted sum of the squares of all the individual elements of the feedback gain matrix. An example is presented to demonstrate the method. In this example, solutions yielding achievable eigenvectors close to the desired eigenvectors are obtained with significant reductions in gain magnitude compared to a solution obtained using a previously developed eigenspace (eigenstructure) assignment method.

  8. The Manifesto Assignment: Study with Women Prisoners

    ERIC Educational Resources Information Center

    Moore, Lisa Jean

    2016-01-01

    Lisa Jean Moore describes a class assignment for her Social and Cultural Change course in which she was required to accommodate the material limitations of teaching within a highly regulated and restricted environment. This assignment, carried out in a women's prison, could be adapted for traditional college settings and travel abroad programs,…

  9. Selling the Home Territory: Assignments for International MBA Students.

    ERIC Educational Resources Information Center

    Reep, Diana C.

    2000-01-01

    Describes the author's approach to a MBA writing course functioning to connect the writing and oral presentation assignments to the students' current jobs. Notes that most international students lack an understanding of American business practices. Develops the assignments around what the students do know. Notes three assignments including a…

  10. "Project ACTS": An Intervention to Increase Organ and Tissue Donation Intentions among African Americans

    ERIC Educational Resources Information Center

    Arriola, Kimberly; Robinson, Dana H.; Thompson, Nancy J.; Perryman, Jennie P.

    2010-01-01

    This study sought to evaluate the effectiveness of "Project ACTS: About Choices in Transplantation and Sharing," which was developed to increase readiness for organ and tissue donation among African American adults. Nine churches (N = 425 participants) were randomly assigned to receive donation education materials currently available to consumers…

  11. Predicting Faculty Intentions to Assign Writing in Their Classes

    ERIC Educational Resources Information Center

    Trafimow, David; Ruckel, Lindsay M.; Stovall, Shelly; Raut, Yogesh J.

    2017-01-01

    Teachers who offer undergraduate courses agree widely on the importance of writing assignments to further undergraduate education. And yet, there is a great deal of variance among teachers in their writing assignments; some teachers assign no writing whatsoever. To determine the variables that influence the decisions of teachers about whether to…

  12. 47 CFR 78.35 - Assignment or transfer of control.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CABLE TELEVISION RELAY SERVICE Applications and Licenses § 78.35 Assignment or transfer of control. (a) No assignment of the license of a cable television relay station or transfer of control of a CARS... 47 Telecommunication 4 2013-10-01 2013-10-01 false Assignment or transfer of control. 78.35...

  13. 47 CFR 78.35 - Assignment or transfer of control.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CABLE TELEVISION RELAY SERVICE Applications and Licenses § 78.35 Assignment or transfer of control. (a) No assignment of the license of a cable television relay station or transfer of control of a CARS... 47 Telecommunication 4 2014-10-01 2014-10-01 false Assignment or transfer of control. 78.35...

  14. 47 CFR 78.35 - Assignment or transfer of control.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CABLE TELEVISION RELAY SERVICE Applications and Licenses § 78.35 Assignment or transfer of control. (a) No assignment of the license of a cable television relay station or transfer of control of a CARS... 47 Telecommunication 4 2010-10-01 2010-10-01 false Assignment or transfer of control. 78.35...

  15. 47 CFR 78.35 - Assignment or transfer of control.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CABLE TELEVISION RELAY SERVICE Applications and Licenses § 78.35 Assignment or transfer of control. (a) No assignment of the license of a cable television relay station or transfer of control of a CARS... 47 Telecommunication 4 2011-10-01 2011-10-01 false Assignment or transfer of control. 78.35...

  16. 42 CFR 435.610 - Assignment of rights to benefits.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Assignment of rights to benefits. 435.610 Section....610 Assignment of rights to benefits. (a) As a condition of eligibility, the agency must require legally able applicants and beneficiaries to: (1) Assign rights to the Medicaid agency to medical support...

  17. 42 CFR 435.610 - Assignment of rights to benefits.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Assignment of rights to benefits. 435.610 Section....610 Assignment of rights to benefits. (a) As a condition of eligibility, the agency must require legally able applicants and beneficiaries to: (1) Assign rights to the Medicaid agency to medical support...

  18. 42 CFR 435.610 - Assignment of rights to benefits.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Assignment of rights to benefits. 435.610 Section....610 Assignment of rights to benefits. (a) As a condition of eligibility, the agency must require legally able applicants and beneficiaries to: (1) Assign rights to the Medicaid agency to medical support...

  19. 47 CFR 78.35 - Assignment or transfer of control.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 47 Telecommunication 4 2012-10-01 2012-10-01 false Assignment or transfer of control. 78.35... CABLE TELEVISION RELAY SERVICE Applications and Licenses § 78.35 Assignment or transfer of control. (a) No assignment of the license of a cable television relay station or transfer of control of a CARS...

  20. Gapminder: An AP Human Geography Lab Assignment

    ERIC Educational Resources Information Center

    Keller, Kenneth H.

    2012-01-01

    This lesson is designed as a lab assignment for Advanced Placement (AP) Human Geography students wherein they use the popular Gapminder web site to compare levels of development in countries from different world regions. For this lesson, it is important for the teacher to practice with Gapminder before giving the assignment to students. (Contains…

  1. 36 CFR 292.22 - Land category assignments.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... availability of this map or maps in the local newspapers of record. (b) Changes in land category assignment.../grazing land so long as the intended use or development is consistent with the standards in § 292.23 and... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Land category assignments...

  2. 12 CFR 563e.28 - Assigned ratings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Assigned ratings. 563e.28 Section 563e.28 Banks... for Assessing Performance § 563e.28 Assigned ratings. (a) Ratings in general. Subject to paragraphs (b... performance under the lending, investment and service tests, the community development test, the small savings...

  3. 45 CFR 12.8 - Assignment of surplus real property.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Assignment of surplus real property. 12.8 Section... UTILIZATION OF SURPLUS REAL PROPERTY FOR PUBLIC HEALTH PURPOSES § 12.8 Assignment of surplus real property. (a... for assignment of surplus real property to the Department for transfer for public health purposes will...

  4. 42 CFR 436.610 - Assignment of rights to benefits.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Assignment of rights to benefits. 436.610 Section... General Financial Eligibility Requirements and Options § 436.610 Assignment of rights to benefits. (a) As...) Assign rights to the Medicaid agency to medical support and to payment for medical care from any third...

  5. 42 CFR 435.610 - Assignment of rights to benefits.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Assignment of rights to benefits. 435.610 Section....610 Assignment of rights to benefits. (a) As a condition of eligibility, the agency must require legally able applicants and recipients to: (1) Assign rights to the Medicaid agency to medical support and...

  6. 42 CFR 436.610 - Assignment of rights to benefits.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Assignment of rights to benefits. 436.610 Section... General Financial Eligibility Requirements and Options § 436.610 Assignment of rights to benefits. (a) As...) Assign rights to the Medicaid agency to medical support and to payment for medical care from any third...

  7. 42 CFR 435.610 - Assignment of rights to benefits.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Assignment of rights to benefits. 435.610 Section....610 Assignment of rights to benefits. (a) As a condition of eligibility, the agency must require legally able applicants and recipients to: (1) Assign rights to the Medicaid agency to medical support and...

  8. 42 CFR 436.610 - Assignment of rights to benefits.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Assignment of rights to benefits. 436.610 Section... General Financial Eligibility Requirements and Options § 436.610 Assignment of rights to benefits. (a) As...) Assign rights to the Medicaid agency to medical support and to payment for medical care from any third...

  9. 42 CFR 436.610 - Assignment of rights to benefits.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Assignment of rights to benefits. 436.610 Section... General Financial Eligibility Requirements and Options § 436.610 Assignment of rights to benefits. (a) As...) Assign rights to the Medicaid agency to medical support and to payment for medical care from any third...

  10. 47 CFR 90.723 - Selection and assignment of frequencies.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... shall specify the number of frequencies requested. All frequencies in this band will be assigned by the... assigned only the number of channels justified to meet their requirements. (d) Phase I base or fixed station receivers utilizing 221-222 MHz frequencies assigned from Sub-band A as designated in § 90.715(b...

  11. 47 CFR 90.723 - Selection and assignment of frequencies.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... shall specify the number of frequencies requested. All frequencies in this band will be assigned by the... assigned only the number of channels justified to meet their requirements. (d) Phase I base or fixed station receivers utilizing 221-222 MHz frequencies assigned from Sub-band A as designated in § 90.715(b...

  12. 47 CFR 90.723 - Selection and assignment of frequencies.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... shall specify the number of frequencies requested. All frequencies in this band will be assigned by the... assigned only the number of channels justified to meet their requirements. (d) Phase I base or fixed station receivers utilizing 221-222 MHz frequencies assigned from Sub-band A as designated in § 90.715(b...

  13. Fleet Assignment Using Collective Intelligence

    NASA Technical Reports Server (NTRS)

    Antoine, Nicolas E.; Bieniawski, Stefan R.; Kroo, Ilan M.; Wolpert, David H.

    2004-01-01

    Airline fleet assignment involves the allocation of aircraft to a set of flights legs in order to meet passenger demand, while satisfying a variety of constraints. Over the course of the day, the routing of each aircraft is determined in order to minimize the number of required flights for a given fleet. The associated flow continuity and aircraft count constraints have led researchers to focus on obtaining quasi-optimal solutions, especially at larger scales. In this paper, the authors propose the application of an agent-based integer optimization algorithm to a "cold start" fleet assignment problem. Results show that the optimizer can successfully solve such highly- constrained problems (129 variables, 184 constraints).

  14. 48 CFR 42.602 - Assignment and location.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Assignment and location. (a) A CACO may be assigned only when (1) the contractor has at least two locations with resident ACO's or (2) the need for a CACO is approved by the agency head or designee (for this... devoted to a single contractor). One of the resident ACO's may be designated to perform the CACO functions...

  15. 48 CFR 42.602 - Assignment and location.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Assignment and location. (a) A CACO may be assigned only when (1) the contractor has at least two locations with resident ACO's or (2) the need for a CACO is approved by the agency head or designee (for this... devoted to a single contractor). One of the resident ACO's may be designated to perform the CACO functions...

  16. Trauma exposure and aggression toward partners and children: Contextual influences of fear and anger.

    PubMed

    Marshall, Amy D; Roettger, Michael E; Mattern, Alexandra C; Feinberg, Mark E; Jones, Damon E

    2018-05-07

    Trauma exposure is a consistent correlate of intimate partner aggression (IPA) and parent-to-child aggression (PCA) perpetration, and difficulties with emotions (particularly fear and anger) are hypothesized to underlie these relations. However, the absence of knowledge of the immediate, contextual influence of emotions on aggression renders existing conclusions tenuous. This study illustrates a new method for studying contextual influences on aggressive behavior. Quarterly for 1 year, 94 men and 109 women with children age 2.5 years at study commencement were interviewed to measure the sequence of behaviors during aggressive incidents as well as the intensity of their emotions immediately prior to initiation of aggression. Within aggressive incidents, the number of acts of men's PCA was predicted by men's greater fear, anger, and trauma exposure, and the positive association between men's trauma exposure and PCA perpetration was especially strong under conditions of high fear and anger. In contrast, men's IPA was predicted by greater fear and anger, but not trauma exposure. Men with low trauma exposure engaged in more IPA under conditions of high fear; among men with high trauma exposure, fear inhibited their IPA persistence. Trauma exposure and fear interacted in the same manner to predict women's IPA, but many other findings among men did not generalize to women's aggression. This study illuminates the utility of simultaneously examining aggression across genders and family dyads, and serves as a foundation for refining theories of trauma and family aggression to account for emotion as a factor that can both motivate and inhibit aggression. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  17. 38 CFR 21.4146 - Assignments of benefits prohibited.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Administration of Educational Assistance Programs Payments; Educational Assistance Allowance § 21.4146 Assignments of benefits prohibited. (a) General... authorized by law. No law specifically authorizes assignments of educational assistance allowances payable...

  18. 38 CFR 21.4146 - Assignments of benefits prohibited.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Administration of Educational Assistance Programs Payments; Educational Assistance Allowance § 21.4146 Assignments of benefits prohibited. (a) General... authorized by law. No law specifically authorizes assignments of educational assistance allowances payable...

  19. Advance care treatment plan (ACT-Plan) for African American family caregivers: a pilot study.

    PubMed

    Bonner, Gloria J; Wang, Edward; Wilkie, Diana J; Ferrans, Carol E; Dancy, Barbara; Watkins, Yashika

    2014-01-01

    Research is limited on end-of-life treatment decisions made by African American family caregivers. In a pilot study, we examined the feasibility of implementing an advance care treatment plan (ACT-Plan), a group-based education intervention, with African American dementia caregivers. Theoretically based, the ACT-Plan included strategies to enhance knowledge, self-efficacy, and behavioral skills to make end-of-life treatment plans in advance. Cardiopulmonary resuscitation, mechanical ventilation, and tube feeding were end-of-life treatments discussed in the ACT-Plan. In a four-week pre/posttest two-group design at urban adult day care centers, 68 caregivers were assigned to the ACT-Plan or attention-control health promotion conditions. Findings strongly suggest that the ACT-Plan intervention is feasible and appropriate for African American caregivers. Self-efficacy and knowledge about dementia, cardiopulmonary resuscitation, mechanical ventilation, and tube feeding increased for ACT-Plan participants but not for the attention-control. More ACT-Plan than attention-control participants developed advance care plans for demented relatives. Findings warrant a randomized efficacy trial.

  20. Modeling regional freight flow assignment through intermodal terminals

    DOT National Transportation Integrated Search

    2005-03-01

    An analytical model is developed to assign regional freight across a multimodal highway and railway network using geographic information systems. As part of the regional planning process, the model is an iterative procedure that assigns multimodal fr...

  1. A New Secondary Structure Assignment Algorithm Using Cα Backbone Fragments

    PubMed Central

    Cao, Chen; Wang, Guishen; Liu, An; Xu, Shutan; Wang, Lincong; Zou, Shuxue

    2016-01-01

    The assignment of secondary structure elements in proteins is a key step in the analysis of their structures and functions. We have developed an algorithm, SACF (secondary structure assignment based on Cα fragments), for secondary structure element (SSE) assignment based on the alignment of Cα backbone fragments with central poses derived by clustering known SSE fragments. The assignment algorithm consists of three steps: First, the outlier fragments on known SSEs are detected. Next, the remaining fragments are clustered to obtain the central fragments for each cluster. Finally, the central fragments are used as a template to make assignments. Following a large-scale comparison of 11 secondary structure assignment methods, SACF, KAKSI and PROSS are found to have similar agreement with DSSP, while PCASSO agrees with DSSP best. SACF and PCASSO show preference to reducing residues in N and C cap regions, whereas KAKSI, P-SEA and SEGNO tend to add residues to the terminals when DSSP assignment is taken as standard. Moreover, our algorithm is able to assign subtle helices (310-helix, π-helix and left-handed helix) and make uniform assignments, as well as to detect rare SSEs in β-sheets or long helices as outlier fragments from other programs. The structural uniformity should be useful for protein structure classification and prediction, while outlier fragments underlie the structure–function relationship. PMID:26978354

  2. Understanding Test-Type Assignment: Why Do Special Educators Make Unexpected Test-Type Assignments?

    ERIC Educational Resources Information Center

    Cho, Hyun-Jeong; Kingston, Neal

    2014-01-01

    We interviewed special educators (a) whose students with disabilities (SWDs) were proficient on the 2008 general education assessment but were assigned to the 2009 alternate assessment based on modified achievement standards (AA-MAS), and (b) whose students with mild disabilities took the 2008 alternate assessment based on alternate achievement…

  3. The assignment of scores procedure for ordinal categorical data.

    PubMed

    Chen, Han-Ching; Wang, Nae-Sheng

    2014-01-01

    Ordinal data are the most frequently encountered type of data in the social sciences. Many statistical methods can be used to process such data. One common method is to assign scores to the data, convert them into interval data, and further perform statistical analysis. There are several authors who have recently developed assigning score methods to assign scores to ordered categorical data. This paper proposes an approach that defines an assigning score system for an ordinal categorical variable based on underlying continuous latent distribution with interpretation by using three case study examples. The results show that the proposed score system is well for skewed ordinal categorical data.

  4. Consistent assignment of nurse aides: association with turnover and absenteeism.

    PubMed

    Castle, Nicholas G

    2013-01-01

    Consistent assignment refers to the same caregivers consistently caring for the same residents almost every time caregivers are on duty. This article examines the association of consistent assignment of nurse aides with turnover and absenteeism. Data came from a survey of nursing home administrators, the Online Survey Certification and Reporting data, and the Area Resource File. The measures were from 2007 and came from 3,941 nursing homes. Multivariate logistic regression models were used to examine turnover and absenteeism. An average of 68% of nursing homes reported using consistent assignment, with 28% of nursing homes using nurse aides consistent assignment at the often recommended level of 85% (or more). Nursing homes using recommended levels of consistent assignment had significantly lower rates of turnover and of absenteeism. In the multivariate analyses, consistent assignment was significantly associated with both lower turnover and lower absenteeism (p < .01). Consistent assignment is a practice recommended by many policy makers, government agencies, and industry advocates. The findings presented here provide some evidence that the use of this staffing practice can be beneficial.

  5. 77 FR 8174 - EPAAR Prescription for Work Assignments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-14

    ...: EPA will amend the EPA Acquisition Regulation (EPAAR) prescription for the work assignment clause. This final rule provides revised language to the prescription for the work assignment clause, incorporating prescriptive language that provides further instructions on the use of the related clause. DATES...

  6. Calibrated peer review assignments for the earth sciences

    USGS Publications Warehouse

    Rudd, J.A.; Wang, V.Z.; Cervato, C.; Ridky, R.W.

    2009-01-01

    Calibrated Peer Review ??? (CPR), a web-based instructional tool developed as part of the National Science Foundation reform initiatives in undergraduate science education, allows instructors to incorporate multiple writing assignments in large courses without overwhelming the instructor. This study reports successful implementation of CPR in a large, introductory geology course and student learning of geoscience content. For each CPR assignment in this study, students studied web-based and paper resources, wrote an essay, and reviewed seven essays (three from the instructor, three from peers, and their own) on the topic. Although many students expressed negative attitudes and concerns, particularly about the peer review process of this innovative instructional approach, they also recognized the learning potential of completing CPR assignments. Comparing instruction on earthquakes and plate boundaries using a CPR assignment vs. an instructional video lecture and homework essay with extensive instructor feedback, students mastered more content via CPR instruction.

  7. Undertaking an International Assignment.

    ERIC Educational Resources Information Center

    Kitinoja, Lisa; And Others

    Agricultural and extension educators interested in international agricultural development must answer several questions to become oriented within the field before undertaking an international assignment. The questions are as follows: (1) why do you want to work internationally? (2) what do you have to offer as a professional? and (3) what is your…

  8. From course assignment paper to publishable manuscript.

    PubMed

    Rew, Lynn

    2012-12-01

    Both undergraduate and graduate nursing students are expected to write numerous papers in their educational programs; however, most of these papers are never published. Many students and faculty lack the skills needed to convert a course assignment paper to a publishable manuscript. The purpose of this article is to describe 10 steps that can transform a course assignment paper into a publishable manuscript. These steps include outlining, clarifying the topic, clearly stating the purpose, identifying an appropriate audience, revising with faculty's feedback, querying journal editors, revising to conform to journal's author guidelines, requesting and responding to peer feedback, and finally editing and proofreading prior to submitting the manuscript. Faculty members are encouraged to make writing assignments that students can then convert to publishable manuscripts. Such publications form an essential cornerstone of professional holistic nursing.

  9. Interactive visual exploration and refinement of cluster assignments.

    PubMed

    Kern, Michael; Lex, Alexander; Gehlenborg, Nils; Johnson, Chris R

    2017-09-12

    With ever-increasing amounts of data produced in biology research, scientists are in need of efficient data analysis methods. Cluster analysis, combined with visualization of the results, is one such method that can be used to make sense of large data volumes. At the same time, cluster analysis is known to be imperfect and depends on the choice of algorithms, parameters, and distance measures. Most clustering algorithms don't properly account for ambiguity in the source data, as records are often assigned to discrete clusters, even if an assignment is unclear. While there are metrics and visualization techniques that allow analysts to compare clusterings or to judge cluster quality, there is no comprehensive method that allows analysts to evaluate, compare, and refine cluster assignments based on the source data, derived scores, and contextual data. In this paper, we introduce a method that explicitly visualizes the quality of cluster assignments, allows comparisons of clustering results and enables analysts to manually curate and refine cluster assignments. Our methods are applicable to matrix data clustered with partitional, hierarchical, and fuzzy clustering algorithms. Furthermore, we enable analysts to explore clustering results in context of other data, for example, to observe whether a clustering of genomic data results in a meaningful differentiation in phenotypes. Our methods are integrated into Caleydo StratomeX, a popular, web-based, disease subtype analysis tool. We show in a usage scenario that our approach can reveal ambiguities in cluster assignments and produce improved clusterings that better differentiate genotypes and phenotypes.

  10. Service offerings and interfaces for the ACTS network of Earth stations

    NASA Technical Reports Server (NTRS)

    Coney, Thom A.

    1988-01-01

    The Advanced Communications Satellite (ACTS) is capable of two modes of communication. Mode 1 is a mesh network of Earth stations using baseband-switched, time-division multiple-access (BBS-TDMA) and hopping beams. Mode 2 is a mesh network using satellite-switched, time-division multiple-access (SS-TDMA) and fixed (or hopping) beams. The purpose of this paper is to present the functional requirements and the design of the ACTS Mode 1 Earth station terrestrial interface. Included among the requirements are that: (1) the interface support standard telecommunications service offerings (i.e., voice, video and data at rates ranging from 9.6 kbps to 44 Mbps); (2) the interface support the unique design characteristics of the ACTS communications systems (e.g., the real time demand assignment of satellite capacity); and (3) the interface support test hardware capable of validating ACTS communications processes. The resulting interface design makes use of an appropriate combination of T1 or T3 multiplexers and a small central office (maximum capacity 56 subscriber lines per unit).

  11. Experiences of Individuals with Visual Impairments in Integrated Physical Education: A Retrospective Study

    ERIC Educational Resources Information Center

    Haegele, Justin A.; Zhu, Xihe

    2017-01-01

    Purpose: The purpose of this retrospective study was to examine the experiences of adults with visual impairments during school-based integrated physical education (PE). Method: An interpretative phenomenological analysis (IPA) research approach was used and 16 adults (ages 21-48 years; 10 women, 6 men) with visual impairments acted as…

  12. Neural Mechanisms of Credit Assignment in a Multicue Environment

    PubMed Central

    Kolling, Nils; Brown, Joshua W.; Rushworth, Matthew

    2016-01-01

    In complex environments, many potential cues can guide a decision or be assigned responsibility for the outcome of the decision. We know little, however, about how humans and animals select relevant information sources that should guide behavior. We show that subjects solve this relevance selection and credit assignment problem by selecting one cue and its association with a particular outcome as the main focus of a hypothesis. To do this, we examined learning while using a task design that allowed us to estimate the focus of each subject's hypotheses on a trial-by-trial basis. When a prediction is confirmed by the outcome, then credit for the outcome is assigned to that cue rather than an alternative. Activity in medial frontal cortex is associated with the assignment of credit to the cue that is the main focus of the hypothesis. However, when the outcome disconfirms a prediction, the focus shifts between cues, and the credit for the outcome is assigned to an alternative cue. This process of reselection for credit assignment to an alternative cue is associated with lateral orbitofrontal cortex. SIGNIFICANCE STATEMENT Learners should infer which features of environments are predictive of significant events, such as rewards. This “credit assignment” problem is particularly challenging when any of several cues might be predictive. We show that human subjects solve the credit assignment problem by implicitly “hypothesizing” which cue is relevant for predicting subsequent outcomes, and then credit is assigned according to this hypothesis. This process is associated with a distinctive pattern of activity in a part of medial frontal cortex. By contrast, when unexpected outcomes occur, hypotheses are redirected toward alternative cues, and this process is associated with activity in lateral orbitofrontal cortex. PMID:26818500

  13. Context-Aware Reviewer Assignment for Trust Enhanced Peer Review

    PubMed Central

    Li, Lei; Wang, Yan; Liu, Guanfeng; Wang, Meng; Wu, Xindong

    2015-01-01

    Reviewer assignment is critical to peer review systems, such as peer-reviewed research conferences or peer-reviewed funding applications, and its effectiveness is a deep concern of all academics. However, there are some problems in existing peer review systems during reviewer assignment. For example, some of the reviewers are much more stringent than others, leading to an unfair final decision, i.e., some submissions (i.e., papers or applications) with better quality are rejected. In this paper, we propose a context-aware reviewer assignment for trust enhanced peer review. More specifically, in our approach, we first consider the research area specific expertise of reviewers, and the institution relevance and co-authorship between reviewers and authors, so that reviewers with the right expertise are assigned to the corresponding submissions without potential conflict of interest. In addition, we propose a novel cross-assignment paradigm, and reviewers are cross-assigned in order to avoid assigning a group of stringent reviewers or a group of lenient reviewers to the same submission. More importantly, on top of them, we propose an academic CONtext-aware expertise relevanCe oriEnted Reviewer cross-assignmenT approach (CONCERT), which aims to effectively estimate the “true” ratings of submissions based on the ratings from all reviewers, even though no prior knowledge exists about the distribution of stringent reviewers and lenient reviewers. The experiments illustrate that compared with existing approaches, our proposed CONCERT approach can less likely assign more than one stringent reviewers or lenient reviewers to a submission simultaneously and significantly reduce the influence of ratings from stringent reviewers and lenient reviewers, leading to trust enhanced peer review and selection, no matter what kind of distributions of stringent reviewers and lenient reviewers are. PMID:26090849

  14. Principals Make Assignments Matter

    ERIC Educational Resources Information Center

    Dougherty, Eleanor

    2013-01-01

    The inner-city high school in Washington, DC, that Guillaume Gendre joined as an assistant principal had a modest reputation for achievement but was nevertheless challenged to raise expectations for student work. In other schools, Gendre had used assignments--a specific kind of instructional task in which students are charged to think about an…

  15. 30 CFR 774.17 - Transfer, assignment, or sale of permit rights.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Transfer, assignment, or sale of permit rights... SYSTEMS UNDER REGULATORY PROGRAMS REVISION; RENEWAL; TRANSFER, ASSIGNMENT, OR SALE OF PERMIT RIGHTS; POST... § 774.17 Transfer, assignment, or sale of permit rights. (a) General. No transfer, assignment, or sale...

  16. 30 CFR 774.17 - Transfer, assignment, or sale of permit rights.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Transfer, assignment, or sale of permit rights... SYSTEMS UNDER REGULATORY PROGRAMS REVISION; RENEWAL; TRANSFER, ASSIGNMENT, OR SALE OF PERMIT RIGHTS; POST... § 774.17 Transfer, assignment, or sale of permit rights. (a) General. No transfer, assignment, or sale...

  17. 47 CFR 52.111 - Toll free number assignment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 47 Telecommunication 3 2013-10-01 2013-10-01 false Toll free number assignment. 52.111 Section 52.111 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) NUMBERING Toll Free Numbers § 52.111 Toll free number assignment. Toll free numbers shall be made available...

  18. 75 FR 55355 - Delegation of Authority and Assignment of Responsibility

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-10

    ... DEPARTMENT OF LABOR Office of the Secretary Delegation of Authority and Assignment of Responsibility Secretary's Order 4-2010 Subject: Delegation of Authority and Assignment of Responsibility to the... delegations and assignments in full force and effect, except as expressly modified herein. 4. Delegation of...

  19. 75 FR 55354 - Delegation of Authority and Assignment of Responsibilities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-10

    ... DEPARTMENT OF LABOR Office of the Secretary Delegation of Authority and Assignment of Responsibilities Secretary's Order 3-2010 Subject: Delegation of Authority and Assignment of Responsibilities to... Secretary to enforce sections 18A and 18B of the FLSA. 4. Delegation of Authority and Assignment of...

  20. The airport gate assignment problem: a survey.

    PubMed

    Bouras, Abdelghani; Ghaleb, Mageed A; Suryahatmaja, Umar S; Salem, Ahmed M

    2014-01-01

    The airport gate assignment problem (AGAP) is one of the most important problems operations managers face daily. Many researches have been done to solve this problem and tackle its complexity. The objective of the task is assigning each flight (aircraft) to an available gate while maximizing both conveniences to passengers and the operational efficiency of airport. This objective requires a solution that provides the ability to change and update the gate assignment data on a real time basis. In this paper, we survey the state of the art of these problems and the various methods to obtain the solution. Our survey covers both theoretical and real AGAP with the description of mathematical formulations and resolution methods such as exact algorithms, heuristic algorithms, and metaheuristic algorithms. We also provide a research trend that can inspire researchers about new problems in this area.

  1. Quality Control Test for Sequence-Phenotype Assignments

    PubMed Central

    Ortiz, Maria Teresa Lara; Rosario, Pablo Benjamín Leon; Luna-Nevarez, Pablo; Gamez, Alba Savin; Martínez-del Campo, Ana; Del Rio, Gabriel

    2015-01-01

    Relating a gene mutation to a phenotype is a common task in different disciplines such as protein biochemistry. In this endeavour, it is common to find false relationships arising from mutations introduced by cells that may be depurated using a phenotypic assay; yet, such phenotypic assays may introduce additional false relationships arising from experimental errors. Here we introduce the use of high-throughput DNA sequencers and statistical analysis aimed to identify incorrect DNA sequence-phenotype assignments and observed that 10–20% of these false assignments are expected in large screenings aimed to identify critical residues for protein function. We further show that this level of incorrect DNA sequence-phenotype assignments may significantly alter our understanding about the structure-function relationship of proteins. We have made available an implementation of our method at http://bis.ifc.unam.mx/en/software/chispas. PMID:25700273

  2. The Airport Gate Assignment Problem: A Survey

    PubMed Central

    Ghaleb, Mageed A.; Salem, Ahmed M.

    2014-01-01

    The airport gate assignment problem (AGAP) is one of the most important problems operations managers face daily. Many researches have been done to solve this problem and tackle its complexity. The objective of the task is assigning each flight (aircraft) to an available gate while maximizing both conveniences to passengers and the operational efficiency of airport. This objective requires a solution that provides the ability to change and update the gate assignment data on a real time basis. In this paper, we survey the state of the art of these problems and the various methods to obtain the solution. Our survey covers both theoretical and real AGAP with the description of mathematical formulations and resolution methods such as exact algorithms, heuristic algorithms, and metaheuristic algorithms. We also provide a research trend that can inspire researchers about new problems in this area. PMID:25506074

  3. 46 CFR 148.01-13 - Assignment and certification.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Assignment and certification. 148.01-13 Section 148.01-13 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) DANGEROUS CARGOES CARRIAGE OF SOLID HAZARDOUS MATERIALS IN BULK General § 148.01-13 Assignment and certification. (a) The National...

  4. Automating Formative and Summative Feedback for Individualised Assignments

    ERIC Educational Resources Information Center

    Hamilton, Ian Robert

    2009-01-01

    Purpose: The purpose of this paper is to report on the rationale behind the use of a unique paper-based individualised accounting assignment, which automated the provision to students of immediate formative and timely summative feedback. Design/methodology/approach: As students worked towards completing their assignment, the package provided…

  5. 25 CFR 225.33 - Assignment of minerals agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Assignment of minerals agreements. 225.33 Section 225.33 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS OIL AND GAS, GEOTHERMAL, AND SOLID MINERALS AGREEMENTS Minerals Agreements § 225.33 Assignment of minerals agreements. An...

  6. 25 CFR 225.33 - Assignment of minerals agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Assignment of minerals agreements. 225.33 Section 225.33 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS OIL AND GAS, GEOTHERMAL, AND SOLID MINERALS AGREEMENTS Minerals Agreements § 225.33 Assignment of minerals agreements. An...

  7. 47 CFR 90.509 - Frequencies available for assignment.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... assignment. Stations engaged in developmental operation may be authorized to use a frequency or frequencies available in the service in which they propose to operate. The number of channels assigned will depend upon the specific requirements of the developmental program and the number of frequencies available in the...

  8. 47 CFR 90.509 - Frequencies available for assignment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... assignment. Stations engaged in developmental operation may be authorized to use a frequency or frequencies available in the service in which they propose to operate. The number of channels assigned will depend upon the specific requirements of the developmental program and the number of frequencies available in the...

  9. 47 CFR 90.509 - Frequencies available for assignment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... assignment. Stations engaged in developmental operation may be authorized to use a frequency or frequencies available in the service in which they propose to operate. The number of channels assigned will depend upon the specific requirements of the developmental program and the number of frequencies available in the...

  10. 25 CFR 225.33 - Assignment of minerals agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Assignment of minerals agreements. 225.33 Section 225.33 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS OIL AND GAS, GEOTHERMAL, AND SOLID MINERALS AGREEMENTS Minerals Agreements § 225.33 Assignment of minerals agreements. An...

  11. 25 CFR 225.33 - Assignment of minerals agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Assignment of minerals agreements. 225.33 Section 225.33 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS OIL AND GAS, GEOTHERMAL, AND SOLID MINERALS AGREEMENTS Minerals Agreements § 225.33 Assignment of minerals agreements. An...

  12. 25 CFR 225.33 - Assignment of minerals agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Assignment of minerals agreements. 225.33 Section 225.33 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS OIL AND GAS, GEOTHERMAL, AND SOLID MINERALS AGREEMENTS Minerals Agreements § 225.33 Assignment of minerals agreements. An...

  13. 47 CFR 24.839 - Transfer of control or assignment of license.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Transfer of control or assignment of license... Broadband PCS § 24.839 Transfer of control or assignment of license. (a) Restrictions on Assignments and Transfers of Licenses for Frequency Blocks C and F won in closed bidding. No assignment or transfer of...

  14. Assignment Procedures in the Air Force Procurement Management Information System.

    ERIC Educational Resources Information Center

    Ward, Joe H., Jr.; And Others

    An overview is presented of the procedure for offering jobs in the Air Force Procurement Management Information System (PROMIS), an assignment system which makes possible the use of human resources research findings to improve individual personnel assignments. A general framework for viewing personnel assignment systems is presented; then job…

  15. 32 CFR 1656.13 - Review of alternative service job assignments.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 6 2014-07-01 2014-07-01 false Review of alternative service job assignments... SERVICE SYSTEM ALTERNATIVE SERVICE § 1656.13 Review of alternative service job assignments. (a) Review of ASW job assignments will be accomplished in accordance with the provisions of this subsection. (b...

  16. 32 CFR 1656.13 - Review of alternative service job assignments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 6 2011-07-01 2011-07-01 false Review of alternative service job assignments... SERVICE SYSTEM ALTERNATIVE SERVICE § 1656.13 Review of alternative service job assignments. (a) Review of ASW job assignments will be accomplished in accordance with the provisions of this subsection. (b...

  17. 32 CFR 1656.13 - Review of alternative service job assignments.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 6 2013-07-01 2013-07-01 false Review of alternative service job assignments... SERVICE SYSTEM ALTERNATIVE SERVICE § 1656.13 Review of alternative service job assignments. (a) Review of ASW job assignments will be accomplished in accordance with the provisions of this subsection. (b...

  18. 32 CFR 1656.13 - Review of alternative service job assignments.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 6 2012-07-01 2012-07-01 false Review of alternative service job assignments... SERVICE SYSTEM ALTERNATIVE SERVICE § 1656.13 Review of alternative service job assignments. (a) Review of ASW job assignments will be accomplished in accordance with the provisions of this subsection. (b...

  19. 7 CFR 1962.6 - Liens and assignments on chattel property.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... and Water (SW) loans. When a new security agreement or chattel mortgage is taken, all existing security items will be described on it. (b) [Reserved] (c) Assignments of upland cotton, rice, wheat and... cotton, rice, wheat and feed grain programs. (1) Obtaining assignments. Assignments will be obtained as...

  20. 7 CFR 1962.6 - Liens and assignments on chattel property.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... and Water (SW) loans. When a new security agreement or chattel mortgage is taken, all existing security items will be described on it. (b) [Reserved] (c) Assignments of upland cotton, rice, wheat and... cotton, rice, wheat and feed grain programs. (1) Obtaining assignments. Assignments will be obtained as...

  1. 7 CFR 1962.6 - Liens and assignments on chattel property.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... and Water (SW) loans. When a new security agreement or chattel mortgage is taken, all existing security items will be described on it. (b) [Reserved] (c) Assignments of upland cotton, rice, wheat and... cotton, rice, wheat and feed grain programs. (1) Obtaining assignments. Assignments will be obtained as...

  2. Supervising Unsuccessful Student Teaching Assignments: Two Terminator's Tales.

    ERIC Educational Resources Information Center

    St. Maurice, Henry

    2001-01-01

    Discusses problems that arise when there is a conflict between a student teacher and the supervising teacher and when a student teacher does not perform satisfactorily. Focuses on how supervisors deal with failed assignments and how beginning teachers improve their teaching and learn from failed assignments. (Contains 21 references.) (JOW)

  3. Scaffolding Assignments and Activities for Undergraduate Research Methods

    ERIC Educational Resources Information Center

    Fisher, Sarah; Justwan, Florian

    2018-01-01

    This article details assignments and lessons created for and tested in research methods courses at two different universities, a large state school and a small liberal arts college. Each assignment or activity utilized scaffolding. Students were asked to push beyond their comfort zone while utilizing concrete and/or creative examples,…

  4. 40 CFR 52.111 - Toll free number assignment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Toll free number assignment. 52.111... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.111 Toll free number assignment. Toll free numbers shall be made available on a first-come, first-served basis unless otherwise directed...

  5. 40 CFR 52.111 - Toll free number assignment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Toll free number assignment. 52.111... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Arizona § 52.111 Toll free number assignment. Toll free numbers shall be made available on a first-come, first-served basis unless otherwise directed...

  6. Socially-Assigned Race, Healthcare Discrimination and Preventive Healthcare Services

    PubMed Central

    MacIntosh, Tracy; Desai, Mayur M.; Lewis, Tene T.; Jones, Beth A.; Nunez-Smith, Marcella

    2013-01-01

    Background Race and ethnicity, typically defined as how individuals self-identify, are complex social constructs. Self-identified racial/ethnic minorities are less likely to receive preventive care and more likely to report healthcare discrimination than self-identified non-Hispanic whites. However, beyond self-identification, these outcomes may vary depending on whether racial/ethnic minorities are perceived by others as being minority or white; this perception is referred to as socially-assigned race. Purpose To examine the associations between socially-assigned race and healthcare discrimination and receipt of selected preventive services. Methods Cross-sectional analysis of the 2004 Behavioral Risk Factor Surveillance System “Reactions to Race” module. Respondents from seven states and the District of Columbia were categorized into 3 groups, defined by a composite of self-identified race/socially-assigned race: Minority/Minority (M/M, n = 6,837), Minority/White (M/W, n = 929), and White/White (W/W, n = 25,913). Respondents were 18 years or older, with 61.7% under age 60; 51.8% of respondents were female. Measures included reported healthcare discrimination and receipt of vaccinations and cancer screenings. Results Racial/ethnic minorities who reported being socially-assigned as minority (M/M) were more likely to report healthcare discrimination compared with those who reported being socially-assigned as white (M/W) (8.9% vs. 5.0%, p = 0.002). Those reporting being socially-assigned as white (M/W and W/W) had similar rates for past-year influenza (73.1% vs. 74.3%) and pneumococcal (69.3% vs. 58.6%) vaccinations; however, rates were significantly lower among M/M respondents (56.2% and 47.6%, respectively, p-values<0.05). There were no significant differences between the M/M and M/W groups in the receipt of cancer screenings. Conclusions Racial/ethnic minorities who reported being socially-assigned as white are more likely to receive preventive

  7. 37 CFR 2.200 - Assignment records open to public inspection.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Assignment records open to... the Patent and Trademark Office § 2.200 Assignment records open to public inspection. (a)(1) Separate...) are open to public inspection at the Office, and copies of those assignment records may be obtained...

  8. Assessment of a Diversity Assignment in a PR Principles Course

    ERIC Educational Resources Information Center

    Gallicano, Tiffany Derville; Stansberry, Kathleen

    2012-01-01

    This study assesses an assignment for incorporating diversity into the principles of public relations course. The assignment is tailored to the challenges of using an active learning approach in a large lecture class. For the assignment, students write a goal, objectives, strategies, an identification of tactics, and evaluation plans for either…

  9. Triage level assignment and nurse characteristics and experience.

    PubMed

    Gómez-Angelats, Elisenda; Miró, Òscar; Bragulat Baur, Ernesto; Antolín Santaliestra, Alberto; Sánchez Sánchez, Miquel

    2018-06-01

    To study the relation between nursing staff demographics and experience and their assignment of triage level in the emergency department. One-year retrospective observational study in the triage area of a tertiary care urban university hospital that applies the Andorran-Spanish triage model. Variables studied were age, gender, nursing experience, triage experience, shift, usual level of emergency work the nurse undertakes, number of triage decisions made, and percentage of patients assigned to each level. Fifty nurses (5 men, 45 women) with a mean (SD) age of 45 (9) years triaged 67 803 patients during the year. Nurses classified more patients in level 5 on the morning shift (7.9%) than on the afternoon shift (5.5%) (P=.003). The difference in the rate of level-5 triage classification became significant when nurses were older (β = 0.092, P=.037) and experience was greater (β = 0.103, P=.017). The number of triages recorded by a nurse was significantly and directly related to the percentage of patients assigned to level 3 (β = 0.003, P=.006) and inversely related to the percentages assigned to level 4 (β = -0.002, P=.008) and level 5 (β = -0.001, P=.017). We found that triage level assignments were related to age, experience, shift, and total number of patients triaged by a nurse.

  10. Contact replacement for NMR resonance assignment.

    PubMed

    Xiong, Fei; Pandurangan, Gopal; Bailey-Kellogg, Chris

    2008-07-01

    Complementing its traditional role in structural studies of proteins, nuclear magnetic resonance (NMR) spectroscopy is playing an increasingly important role in functional studies. NMR dynamics experiments characterize motions involved in target recognition, ligand binding, etc., while NMR chemical shift perturbation experiments identify and localize protein-protein and protein-ligand interactions. The key bottleneck in these studies is to determine the backbone resonance assignment, which allows spectral peaks to be mapped to specific atoms. This article develops a novel approach to address that bottleneck, exploiting an available X-ray structure or homology model to assign the entire backbone from a set of relatively fast and cheap NMR experiments. We formulate contact replacement for resonance assignment as the problem of computing correspondences between a contact graph representing the structure and an NMR graph representing the data; the NMR graph is a significantly corrupted, ambiguous version of the contact graph. We first show that by combining connectivity and amino acid type information, and exploiting the random structure of the noise, one can provably determine unique correspondences in polynomial time with high probability, even in the presence of significant noise (a constant number of noisy edges per vertex). We then detail an efficient randomized algorithm and show that, over a variety of experimental and synthetic datasets, it is robust to typical levels of structural variation (1-2 AA), noise (250-600%) and missings (10-40%). Our algorithm achieves very good overall assignment accuracy, above 80% in alpha-helices, 70% in beta-sheets and 60% in loop regions. Our contact replacement algorithm is implemented in platform-independent Python code. The software can be freely obtained for academic use by request from the authors.

  11. Students' Achievement and Homework Assignment Strategies.

    PubMed

    Fernández-Alonso, Rubén; Álvarez-Díaz, Marcos; Suárez-Álvarez, Javier; Muñiz, José

    2017-01-01

    The optimum time students should spend on homework has been widely researched although the results are far from unanimous. The main objective of this research is to analyze how homework assignment strategies in schools affect students' academic performance and the differences in students' time spent on homework. Participants were a representative sample of Spanish adolescents ( N = 26,543) with a mean age of 14.4 (±0.75), 49.7% girls. A test battery was used to measure academic performance in four subjects: Spanish, Mathematics, Science, and Citizenship. A questionnaire allowed the measurement of the indicators used for the description of homework and control variables. Two three-level hierarchical-linear models (student, school, autonomous community) were produced for each subject being evaluated. The relationship between academic results and homework time is negative at the individual level but positive at school level. An increase in the amount of homework a school assigns is associated with an increase in the differences in student time spent on homework. An optimum amount of homework is proposed which schools should assign to maximize gains in achievement for students overall.

  12. Students' Achievement and Homework Assignment Strategies

    PubMed Central

    Fernández-Alonso, Rubén; Álvarez-Díaz, Marcos; Suárez-Álvarez, Javier; Muñiz, José

    2017-01-01

    The optimum time students should spend on homework has been widely researched although the results are far from unanimous. The main objective of this research is to analyze how homework assignment strategies in schools affect students' academic performance and the differences in students' time spent on homework. Participants were a representative sample of Spanish adolescents (N = 26,543) with a mean age of 14.4 (±0.75), 49.7% girls. A test battery was used to measure academic performance in four subjects: Spanish, Mathematics, Science, and Citizenship. A questionnaire allowed the measurement of the indicators used for the description of homework and control variables. Two three-level hierarchical-linear models (student, school, autonomous community) were produced for each subject being evaluated. The relationship between academic results and homework time is negative at the individual level but positive at school level. An increase in the amount of homework a school assigns is associated with an increase in the differences in student time spent on homework. An optimum amount of homework is proposed which schools should assign to maximize gains in achievement for students overall. PMID:28326046

  13. Conceptualizing Patient Barriers to Nonadherence with Homework Assignments

    ERIC Educational Resources Information Center

    Kazantzis, Nikolaos; Shinkfield, Gregg

    2007-01-01

    Nonadherence with homework assignments and, by implication, "barriers" to homework assignments are a frequent occurrence in the practice of standard cognitive therapy (Beck, A. T., Rush, A. J., Shaw, B. F., Emery, G. (1979). "Cognitive therapy of depression." New York: The Guilford Press). The clinical examples in this article illustrate some of…

  14. ICT Teachers' Assigned Roles and Expectations from Them

    ERIC Educational Resources Information Center

    Topu, Fatma Burcu; Goktas, Yuksel

    2012-01-01

    The aim of this study was to provide a better understanding of ICT teachers' assigned position and to determine school administrators' and other teachers' perceptions towards ICT teachers and these teachers' positions, and to reveal the similar and discrepant aspects of their tertiary education and the roles (work and responsibilities) assigned to…

  15. Game theory and traffic assignment.

    DOT National Transportation Integrated Search

    2013-09-01

    Traffic assignment is used to determine the number of users on roadway links in a network. While this problem has : been widely studied in transportation literature, its use of the concept of equilibrium has attracted considerable interest : in the f...

  16. Business Etiquette (My Favorite Assignment).

    ERIC Educational Resources Information Center

    Forbes, Cassie

    1990-01-01

    Describes an assignment for a business communication course in which students give an oral presentation on some aspect of business manners and etiquette, thus increasing their awareness of the impact of social graces on communication in the business setting. (SR)

  17. Simulated annealing algorithm for solving chambering student-case assignment problem

    NASA Astrophysics Data System (ADS)

    Ghazali, Saadiah; Abdul-Rahman, Syariza

    2015-12-01

    The problem related to project assignment problem is one of popular practical problem that appear nowadays. The challenge of solving the problem raise whenever the complexity related to preferences, the existence of real-world constraints and problem size increased. This study focuses on solving a chambering student-case assignment problem by using a simulated annealing algorithm where this problem is classified under project assignment problem. The project assignment problem is considered as hard combinatorial optimization problem and solving it using a metaheuristic approach is an advantage because it could return a good solution in a reasonable time. The problem of assigning chambering students to cases has never been addressed in the literature before. For the proposed problem, it is essential for law graduates to peruse in chambers before they are qualified to become legal counselor. Thus, assigning the chambering students to cases is a critically needed especially when involving many preferences. Hence, this study presents a preliminary study of the proposed project assignment problem. The objective of the study is to minimize the total completion time for all students in solving the given cases. This study employed a minimum cost greedy heuristic in order to construct a feasible initial solution. The search then is preceded with a simulated annealing algorithm for further improvement of solution quality. The analysis of the obtained result has shown that the proposed simulated annealing algorithm has greatly improved the solution constructed by the minimum cost greedy heuristic. Hence, this research has demonstrated the advantages of solving project assignment problem by using metaheuristic techniques.

  18. 33 CFR 3.01-5 - Assignment of functions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Assignment of functions. 3.01-5... Provisions § 3.01-5 Assignment of functions. Section 888 of Pub. L. 107-296, 116 Stat. 2135, authorizes the Commandant of the Coast Guard to exercise certain functions, powers, and duties vested in the Secretary of...

  19. 7 CFR 1404.4 - Execution of assignment form.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... assignment form. (a)(1) The assignment of any FSA or CCC payment must be made by the execution of Form CCC-36 or Forms CCC-251 and CCC-252. Form CCC-36 is applicable to payments made under programs administered... applicable to any other program which is administered by a county ASC committee. Forms CCC-251 and 252 are...

  20. 7 CFR 1404.4 - Execution of assignment form.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... assignment form. (a)(1) The assignment of any FSA or CCC payment must be made by the execution of Form CCC-36 or Forms CCC-251 and CCC-252. Form CCC-36 is applicable to payments made under programs administered... applicable to any other program which is administered by a county ASC committee. Forms CCC-251 and 252 are...

  1. 7 CFR 1404.4 - Execution of assignment form.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... assignment form. (a)(1) The assignment of any FSA or CCC payment must be made by the execution of Form CCC-36 or Forms CCC-251 and CCC-252. Form CCC-36 is applicable to payments made under programs administered... applicable to any other program which is administered by a county ASC committee. Forms CCC-251 and 252 are...

  2. 7 CFR 1404.4 - Execution of assignment form.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... assignment form. (a)(1) The assignment of any FSA or CCC payment must be made by the execution of Form CCC-36 or Forms CCC-251 and CCC-252. Form CCC-36 is applicable to payments made under programs administered... applicable to any other program which is administered by a county ASC committee. Forms CCC-251 and 252 are...

  3. 7 CFR 1404.4 - Execution of assignment form.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... assignment form. (a)(1) The assignment of any FSA or CCC payment must be made by the execution of Form CCC-36 or Forms CCC-251 and CCC-252. Form CCC-36 is applicable to payments made under programs administered... applicable to any other program which is administered by a county ASC committee. Forms CCC-251 and 252 are...

  4. 76 FR 55880 - Recording Assignments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-09

    ... DEPARTMENT OF COMMERCE United States Patent and Trademark Office Recording Assignments ACTION: Proposed collection; comment request. SUMMARY: The United States Patent and Trademark Office (USPTO), as... Information Officer, United States Patent and Trademark Office, P.O. Box 1450, Alexandria, VA 22313-1450...

  5. 7 CFR 1450.9 - Assignments.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Assignments. 1450.9 Section 1450.9 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  6. 7 CFR 1450.9 - Assignments.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Assignments. 1450.9 Section 1450.9 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  7. 7 CFR 1450.9 - Assignments.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Assignments. 1450.9 Section 1450.9 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  8. 7 CFR 1450.9 - Assignments.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Assignments. 1450.9 Section 1450.9 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS BIOMASS CROP ASSISTANCE PROGRAM (BCAP) Common Provisions...

  9. Fleet Assignment Using Collective Intelligence

    NASA Technical Reports Server (NTRS)

    Antoine, Nicolas E.; Bieniawski, Stefan R.; Kroo, Ilan M.; Wolpert, David H.

    2004-01-01

    Product distribution theory is a new collective intelligence-based framework for analyzing and controlling distributed systems. Its usefulness in distributed stochastic optimization is illustrated here through an airline fleet assignment problem. This problem involves the allocation of aircraft to a set of flights legs in order to meet passenger demand, while satisfying a variety of linear and non-linear constraints. Over the course of the day, the routing of each aircraft is determined in order to minimize the number of required flights for a given fleet. The associated flow continuity and aircraft count constraints have led researchers to focus on obtaining quasi-optimal solutions, especially at larger scales. In this paper, the authors propose the application of this new stochastic optimization algorithm to a non-linear objective cold start fleet assignment problem. Results show that the optimizer can successfully solve such highly-constrained problems (130 variables, 184 constraints).

  10. Automated and assisted RNA resonance assignment using NMR chemical shift statistics

    PubMed Central

    Aeschbacher, Thomas; Schmidt, Elena; Blatter, Markus; Maris, Christophe; Duss, Olivier; Allain, Frédéric H.-T.; Güntert, Peter; Schubert, Mario

    2013-01-01

    The three-dimensional structure determination of RNAs by NMR spectroscopy relies on chemical shift assignment, which still constitutes a bottleneck. In order to develop more efficient assignment strategies, we analysed relationships between sequence and 1H and 13C chemical shifts. Statistics of resonances from regularly Watson–Crick base-paired RNA revealed highly characteristic chemical shift clusters. We developed two approaches using these statistics for chemical shift assignment of double-stranded RNA (dsRNA): a manual approach that yields starting points for resonance assignment and simplifies decision trees and an automated approach based on the recently introduced automated resonance assignment algorithm FLYA. Both strategies require only unlabeled RNAs and three 2D spectra for assigning the H2/C2, H5/C5, H6/C6, H8/C8 and H1′/C1′ chemical shifts. The manual approach proved to be efficient and robust when applied to the experimental data of RNAs with a size between 20 nt and 42 nt. The more advanced automated assignment approach was successfully applied to four stem-loop RNAs and a 42 nt siRNA, assigning 92–100% of the resonances from dsRNA regions correctly. This is the first automated approach for chemical shift assignment of non-exchangeable protons of RNA and their corresponding 13C resonances, which provides an important step toward automated structure determination of RNAs. PMID:23921634

  11. Effectiveness of long-acting antipsychotics in clinical practice : 1. A retrospective, 18-month follow up and comparison between paliperidone palmitate, risperidone long-acting injection and zuclopenthixol decanoate

    PubMed Central

    Cordiner, Matthew; Shajahan, Polash; McAvoy, Sarah; Bashir, Muhammad; Taylor, Mark

    2016-01-01

    Objectives: In the UK, nine different compounds are available as long-acting antipsychotic injections (LAIs). There are few clinical guidelines for determining which LAIs are most effective in specific patient groups. To measure the clinical effectiveness of LAIs we aimed to determine the now-established concept of antipsychotic discontinuation rates and measure Clinical Global Impression (CGI) outcomes. Method: The population (n was approximately 560,000) was a secondary care NHS adult mental health service in Lanarkshire, Scotland, UK. This was a retrospective, electronic case note search of LAI-naïve patients commenced on paliperidone palmitate (n = 31), risperidone long-acting injection (RLAI) (n = 102) or zuclopenthixol decanoate (n = 105), with an 18-month follow up. Kaplan–Meier survival statistics for discontinuation rates and hospital admission were calculated. CGI severity and improvement scores were retrospectively assigned by the investigating team. Results: Paliperidone palmitate performed less favourably than risperidone long-acting injection (RLAI) or zuclopenthixol decanoate. Paliperidone palmitate had higher discontinuation rates due to any cause, inefficacy and increased hospitalization risk. Paliperidone palmitate had the smallest proportion of patients assigned a clinically desirable CGI-I score of 1 (very much improved) or 2 (much improved). Conclusions: Paliperidone palmitate had less favourable discontinuation and CGI outcomes compared with RLAI and zuclopenthixol decanoate. This could not be adequately explained by patients in the paliperidone group being more chronically or severely unwell, nor by the presence of comorbidities such as alcohol or substance misuse, or by the use of lower mean dosages compared with RLAI or zuclopenthixol decanoate. We considered that prescribers are familiarizing themselves with paliperidone and outcomes may improve over time. PMID:26913175

  12. Covariance NMR Processing and Analysis for Protein Assignment.

    PubMed

    Harden, Bradley J; Frueh, Dominique P

    2018-01-01

    During NMR resonance assignment it is often necessary to relate nuclei to one another indirectly, through their common correlations to other nuclei. Covariance NMR has emerged as a powerful technique to correlate such nuclei without relying on error-prone peak peaking. However, false-positive artifacts in covariance spectra have impeded a general application to proteins. We recently introduced pre- and postprocessing steps to reduce the prevalence of artifacts in covariance spectra, allowing for the calculation of a variety of 4D covariance maps obtained from diverse combinations of pairs of 3D spectra, and we have employed them to assign backbone and sidechain resonances in two large and challenging proteins. In this chapter, we present a detailed protocol describing how to (1) properly prepare existing 3D spectra for covariance, (2) understand and apply our processing script, and (3) navigate and interpret the resulting 4D spectra. We also provide solutions to a number of errors that may occur when using our script, and we offer practical advice when assigning difficult signals. We believe such 4D spectra, and covariance NMR in general, can play an integral role in the assignment of NMR signals.

  13. 48 CFR 1342.102 - Assignment of contract audit services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Assignment of contract audit services. 1342.102 Section 1342.102 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CONTRACT MANAGEMENT CONTRACT ADMINISTRATION Contract Audit Services 1342.102 Assignment of contract audit...

  14. Evaluation of a UMLS Auditing Process of Semantic Type Assignments

    PubMed Central

    Gu, Huanying; Hripcsak, George; Chen, Yan; Morrey, C. Paul; Elhanan, Gai; Cimino, James J.; Geller, James; Perl, Yehoshua

    2007-01-01

    The UMLS is a terminological system that integrates many source terminologies. Each concept in the UMLS is assigned one or more semantic types from the Semantic Network, an upper level ontology for biomedicine. Due to the complexity of the UMLS, errors exist in the semantic type assignments. Finding assignment errors may unearth modeling errors. Even with sophisticated tools, discovering assignment errors requires manual review. In this paper we describe the evaluation of an auditing project of UMLS semantic type assignments. We studied the performance of the auditors who reviewed potential errors. We found that four auditors, interacting according to a multi-step protocol, identified a high rate of errors (one or more errors in 81% of concepts studied) and that results were sufficiently reliable (0.67 to 0.70) for the two most common types of errors. However, reliability was low for each individual auditor, suggesting that review of potential errors is resource-intensive. PMID:18693845

  15. 47 CFR 73.4104 - FM assignment policies and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false FM assignment policies and procedures. 73.4104 Section 73.4104 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.4104 FM assignment policies and...

  16. 47 CFR 73.4104 - FM assignment policies and procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 4 2011-10-01 2011-10-01 false FM assignment policies and procedures. 73.4104 Section 73.4104 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.4104 FM assignment policies and...

  17. 42 CFR 414.918 - Assignment.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 3 2011-10-01 2011-10-01 false Assignment. 414.918 Section 414.918 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM PAYMENT FOR PART B MEDICAL AND OTHER HEALTH SERVICES Payment for Drugs and Biologicals Under Part...

  18. 42 CFR 414.918 - Assignment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Assignment. 414.918 Section 414.918 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM PAYMENT FOR PART B MEDICAL AND OTHER HEALTH SERVICES Payment for Drugs and Biologicals Under Part...

  19. Students' Perspectives of Same-Day Clinical Assignments: A Qualitative Descriptive Study.

    PubMed

    Harris, Allyssa L; Stamp, Kelly D

    2016-01-01

    The clinical experience is essential to the nursing education process, but the process by which students are assigned patients has remained unchanged for decades. The purpose of this qualitative descriptive study was to determine the acceptability of a same-day clinical assignment process from the perspective of pre-licensure nursing students. Students' (n = 104) perceptions of the same-day clinical assignment process were collected via focus groups. Two themes emerged that may assist educators in implementing new methods for clinical assignments.

  20. 42 CFR 433.145 - Assignment of rights to benefits-State plan requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Assignment of rights to benefits-State plan... Liability Assignment of Rights to Benefits § 433.145 Assignment of rights to benefits—State plan... beneficiary is required to: (1) Assign to the Medicaid agency his or her rights, or the rights of any other...

  1. 42 CFR 433.145 - Assignment of rights to benefits-State plan requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Assignment of rights to benefits-State plan... Liability Assignment of Rights to Benefits § 433.145 Assignment of rights to benefits—State plan... recipient is required to: (1) Assign to the Medicaid agency his or her rights, or the rights of any other...

  2. 42 CFR 433.145 - Assignment of rights to benefits-State plan requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Assignment of rights to benefits-State plan... Liability Assignment of Rights to Benefits § 433.145 Assignment of rights to benefits—State plan... beneficiary is required to: (1) Assign to the Medicaid agency his or her rights, or the rights of any other...

  3. 42 CFR 433.145 - Assignment of rights to benefits-State plan requirements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Assignment of rights to benefits-State plan... Liability Assignment of Rights to Benefits § 433.145 Assignment of rights to benefits—State plan... beneficiary is required to: (1) Assign to the Medicaid agency his or her rights, or the rights of any other...

  4. 42 CFR 433.145 - Assignment of rights to benefits-State plan requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Assignment of rights to benefits-State plan... Liability Assignment of Rights to Benefits § 433.145 Assignment of rights to benefits—State plan... recipient is required to: (1) Assign to the Medicaid agency his or her rights, or the rights of any other...

  5. Protein assignments without peak lists using higher-order spectra.

    PubMed

    Benison, Gregory; Berkholz, Donald S; Barbar, Elisar

    2007-12-01

    Despite advances in automating the generation and manipulation of peak lists for assigning biomolecules, there are well-known advantages to working directly with spectra: the eye is still superior to computer algorithms when it comes to picking out peak relationships from contour plots in the presence of confounding factors such as noise, overlap, and spectral artifacts. Here, we present constructs called higher-order spectra for identifying, through direct visual examination, many of the same relationships typically identified by searching peak lists, making them another addition to the set of tools (alongside peak picking and automated assignment) that can be used to solve the assignment problem. The technique is useful for searching for correlated peaks in any spectrum type. Application of this technique to novel, complete sequential assignment of two proteins (AhpFn and IC74(84-143)) is demonstrated. The program "burrow-owl" for the generation and display of higher-order spectra is available at (http://sourceforge.net/projects/burrow-owl) or from the authors.

  6. Integrating Academic Journal Review Assignments into a Graduate Business Leadership Course

    ERIC Educational Resources Information Center

    Schultz, Jennifer L.; Agrimonti, Lisa M.; Higbee, Jeanne L.

    2016-01-01

    Graduate course assignments that are pragmatic, challenging, scaffold prior learning, and support academic career aspirations can be difficult to create and even more problematic to assess for even the most experienced faculty. This paper presents a class assignment that incorporated a real-world journal reviewing assignment into an elective…

  7. 10 CFR 611.110 - Assignment or transfer of loans.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Assignment or transfer of loans. 611.110 Section 611.110 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS ADVANCED TECHNOLOGY VEHICLES MANUFACTURER ASSISTANCE PROGRAM Direct Loan Program § 611.110 Assignment or transfer of loans. (a) The Loan Documents may...

  8. Teachers and Seating Arrangements and Assignments: A Qualitative Study

    ERIC Educational Resources Information Center

    Kinahan, Mary P.

    2017-01-01

    Seating assignments and arrangements are utilized in every school classroom. This qualitative study explored the perceptions that teachers have on seating assignments and arrangements to gain a better understanding of how they make design considerations which impact their students. The questions that guide this study are: How do elementary…

  9. A Poster Assignment Connects Information Literacy and Writing Skills

    ERIC Educational Resources Information Center

    Waters, Natalie

    2015-01-01

    This paper describes the implementation of a poster assignment in a writing and information literacy course required for undergraduate Life Sciences and Environmental Biology majors with the Faculty of Agricultural and Environmental Sciences at McGill University. The assignment was introduced in response to weaknesses identified through course…

  10. 7 CFR 760.911 - Offsets, assignments, and debt settlement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Offsets, assignments, and debt settlement. 760.911 Section 760.911 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY... § 760.911 Offsets, assignments, and debt settlement. (a) Any payment to any participant will be made...

  11. 7 CFR 760.911 - Offsets, assignments, and debt settlement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 7 2013-01-01 2013-01-01 false Offsets, assignments, and debt settlement. 760.911 Section 760.911 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY... § 760.911 Offsets, assignments, and debt settlement. (a) Any payment to any participant will be made...

  12. 7 CFR 760.911 - Offsets, assignments, and debt settlement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Offsets, assignments, and debt settlement. 760.911 Section 760.911 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY... § 760.911 Offsets, assignments, and debt settlement. (a) Any payment to any participant will be made...

  13. 7 CFR 760.911 - Offsets, assignments, and debt settlement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Offsets, assignments, and debt settlement. 760.911 Section 760.911 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY... § 760.911 Offsets, assignments, and debt settlement. (a) Any payment to any participant will be made...

  14. 7 CFR 760.911 - Offsets, assignments, and debt settlement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Offsets, assignments, and debt settlement. 760.911 Section 760.911 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY... § 760.911 Offsets, assignments, and debt settlement. (a) Any payment to any participant will be made...

  15. 13 CFR 400.210 - Assignment or transfer of loans.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Assignment or transfer of loans. 400.210 Section 400.210 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.210 Assignment or transfer of loans. (a...

  16. 13 CFR 400.210 - Assignment or transfer of loans.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false Assignment or transfer of loans. 400.210 Section 400.210 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.210 Assignment or transfer of loans. (a...

  17. 13 CFR 400.210 - Assignment or transfer of loans.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Assignment or transfer of loans. 400.210 Section 400.210 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL GUARANTEE LOAN PROGRAM Steel Guarantee Loans § 400.210 Assignment or transfer of loans. (a...

  18. 26 CFR 1.401(a)-13 - Assignment or alienation of benefits.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Assignment or alienation of benefits. 1.401(a...)-13 Assignment or alienation of benefits. (a) Scope of the regulations. This section applies only to..., provided for employer contributions. (b) No assignment or alienation—(1) General rule. Under section 401(a...

  19. 42 CFR 421.114 - Assignment and reassignment of providers by CMS.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Assignment and reassignment of providers by CMS. 421.114 Section 421.114 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH... Assignment and reassignment of providers by CMS. CMS may assign or reassign any provider to any intermediary...

  20. Searching objective criteria for patient assignment in addiction treatment.

    PubMed

    López-Goñi, José J; Fernández-Montalvo, Javier; Arteaga, Alfonso; Esarte, Sonia

    2017-05-01

    The main aim of this study was to objectify the treatment assignment criteria used in a clinical centre for addiction treatment in Spain. A sample of 162 patients (87 inpatients and 75 outpatients) who sought treatment between 2010 and 2012 was assessed. Clinical characteristics (addiction severity, psychopathological symptoms, impulsiveness and maladjustment) of the two treatment groups (inpatient and outpatient) into which patients were assigned according to the clinical criteria of therapists were analysed to identify which variables were more relevant for patient placement. Moreover, the therapeutic progression of patients who met and did not meet the assignment criteria received was studied. According to the results, a score above 4 in the family/social support area of the European Addiction Severity Index (EuropASI), or, in cases of a score between 2 and 4 in the family/social area of EuropASI, a score above 2 in the partner subscale of the Maladjustment Scale correctly classified 73.5% of cases (96.6% of inpatients and 46.7% of outpatients). Comparisons of therapeutic results depending on matching or mismatching these assignment criteria showed a larger effect size in mismatching patient assignment criteria for outpatient treatment. The results obtained in this study provide an objective criterion for addicted patient placement. Moreover, from a cost-effective perspective, they question the necessity of inpatient treatment in most cases, demonstrating that outpatient treatment is a sufficient level of care. This study addresses the approach to assigning patients to the treatment modality that best fits them, implementing the least expensive level of care needed to achieve treatment success. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. DNATCO: assignment of DNA conformers at dnatco.org.

    PubMed

    Černý, Jiří; Božíková, Paulína; Schneider, Bohdan

    2016-07-08

    The web service DNATCO (dnatco.org) classifies local conformations of DNA molecules beyond their traditional sorting to A, B and Z DNA forms. DNATCO provides an interface to robust algorithms assigning conformation classes called NTC: to dinucleotides extracted from DNA-containing structures uploaded in PDB format version 3.1 or above. The assigned dinucleotide NTC: classes are further grouped into DNA structural alphabet NTA: , to the best of our knowledge the first DNA structural alphabet. The results are presented at two levels: in the form of user friendly visualization and analysis of the assignment, and in the form of a downloadable, more detailed table for further analysis offline. The website is free and open to all users and there is no login requirement. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  2. Practice Makes Progress? Homework Assignments and Outcome in Treatment of Cocaine Dependence

    PubMed Central

    Carroll, Kathleen M.; Nich, Charla; Ball, Samuel A.

    2008-01-01

    The relationship between treatment outcome and the extent to which participants completed homework assignments was evaluated among 60 cocaine-dependent individuals assigned to cognitive–behavioral therapy (CBT). Homework was assigned in 72% of all sessions and initiated by participants in 48% of the sessions in which it was assigned. Completion of homework was unrelated to participants' baseline characteristics and several indicators of treatment compliance. Participants who completed more homework assignments demonstrated significantly greater increases in the quantity and quality of their coping skills and used significantly less cocaine during treatment and through a 1-year follow-up. These data suggest that the extent to which participants are willing to complete extrasession assignments may be an important mediator of response to CBT. PMID:16173864

  3. 25 CFR 215.20 - Assignment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Assignment. 215.20 Section 215.20 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEAD AND ZINC MINING OPERATIONS AND LEASES..., sublessee, or sublettee shall be qualified to hold such lease under the regulations in this part and shall...

  4. 25 CFR 215.20 - Assignment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Assignment. 215.20 Section 215.20 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ENERGY AND MINERALS LEAD AND ZINC MINING OPERATIONS AND LEASES..., sublessee, or sublettee shall be qualified to hold such lease under the regulations in this part and shall...

  5. The Well-Tempered Mathematics Assignment.

    ERIC Educational Resources Information Center

    Rishel, Thomas W.

    Mathematics faculty around the United States are using writing assignments in a variety of ways. A mathematics teacher at Alma College, Michigan, has students write mathematical autobiographies, keep a reading logbook, and write letters to other students about the course, letters to instructors about the topics, or about what they do not…

  6. 48 CFR 1352.227-70 - Rights in data, assignment of copyright.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., Rights in Data—Special Works, the contractor agrees to assign copyright to data, including reports and... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Rights in data, assignment....227-70 Rights in data, assignment of copyright. As prescribed in 48 CFR 1327.404-4(a), insert the...

  7. More reliable protein NMR peak assignment via improved 2-interval scheduling.

    PubMed

    Chen, Zhi-Zhong; Lin, Guohui; Rizzi, Romeo; Wen, Jianjun; Xu, Dong; Xu, Ying; Jiang, Tao

    2005-03-01

    Protein NMR peak assignment refers to the process of assigning a group of "spin systems" obtained experimentally to a protein sequence of amino acids. The automation of this process is still an unsolved and challenging problem in NMR protein structure determination. Recently, protein NMR peak assignment has been formulated as an interval scheduling problem (ISP), where a protein sequence P of amino acids is viewed as a discrete time interval I (the amino acids on P one-to-one correspond to the time units of I), each subset S of spin systems that are known to originate from consecutive amino acids from P is viewed as a "job" j(s), the preference of assigning S to a subsequence P of consecutive amino acids on P is viewed as the profit of executing job j(s) in the subinterval of I corresponding to P, and the goal is to maximize the total profit of executing the jobs (on a single machine) during I. The interval scheduling problem is max SNP-hard in general; but in the real practice of protein NMR peak assignment, each job j(s) usually requires at most 10 consecutive time units, and typically the jobs that require one or two consecutive time units are the most difficult to assign/schedule. In order to solve these most difficult assignments, we present an efficient 13/7-approximation algorithm for the special case of the interval scheduling problem where each job takes one or two consecutive time units. Combining this algorithm with a greedy filtering strategy for handling long jobs (i.e., jobs that need more than two consecutive time units), we obtain a new efficient heuristic for protein NMR peak assignment. Our experimental study shows that the new heuristic produces the best peak assignment in most of the cases, compared with the NMR peak assignment algorithms in the recent literature. The above algorithm is also the first approximation algorithm for a nontrivial case of the well-known interval scheduling problem that breaks the ratio 2 barrier.

  8. 47 CFR 90.723 - Selection and assignment of frequencies.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 5 2011-10-01 2011-10-01 false Selection and assignment of frequencies. 90.723... 220-222 MHz Band § 90.723 Selection and assignment of frequencies. (a) Phase II applications for... systems, 10-channel EA systems, 15-channel Regional systems, public safety/mutual aid use, or emergency...

  9. A Survey of Automated Assessment Approaches for Programming Assignments

    ERIC Educational Resources Information Center

    Ala-Mutka, Kirsti M.

    2005-01-01

    Practical programming is one of the basic skills pursued in computer science education. On programming courses, the coursework consists of programming assignments that need to be assessed from different points of view. Since the submitted assignments are executable programs with a formal structure, some features can be assessed automatically. The…

  10. The Eco-Sculpture Assignment: Using Art to Scaffold Metacognition

    ERIC Educational Resources Information Center

    Polegato, Rosemary

    2014-01-01

    The Eco-Sculpture Assignment demonstrates that art may be used as a conduit to scaffold metacognition in marketing courses. Theoretical underpinnings are drawn from the literature on pedagogy used in general, marketing, and art education contexts. The assignment is described in detail, followed by examples of learner response that illustrate…

  11. A Markov Random Field Framework for Protein Side-Chain Resonance Assignment

    NASA Astrophysics Data System (ADS)

    Zeng, Jianyang; Zhou, Pei; Donald, Bruce Randall

    Nuclear magnetic resonance (NMR) spectroscopy plays a critical role in structural genomics, and serves as a primary tool for determining protein structures, dynamics and interactions in physiologically-relevant solution conditions. The current speed of protein structure determination via NMR is limited by the lengthy time required in resonance assignment, which maps spectral peaks to specific atoms and residues in the primary sequence. Although numerous algorithms have been developed to address the backbone resonance assignment problem [68,2,10,37,14,64,1,31,60], little work has been done to automate side-chain resonance assignment [43, 48, 5]. Most previous attempts in assigning side-chain resonances depend on a set of NMR experiments that record through-bond interactions with side-chain protons for each residue. Unfortunately, these NMR experiments have low sensitivity and limited performance on large proteins, which makes it difficult to obtain enough side-chain resonance assignments. On the other hand, it is essential to obtain almost all of the side-chain resonance assignments as a prerequisite for high-resolution structure determination. To overcome this deficiency, we present a novel side-chain resonance assignment algorithm based on alternative NMR experiments measuring through-space interactions between protons in the protein, which also provide crucial distance restraints and are normally required in high-resolution structure determination. We cast the side-chain resonance assignment problem into a Markov Random Field (MRF) framework, and extend and apply combinatorial protein design algorithms to compute the optimal solution that best interprets the NMR data. Our MRF framework captures the contact map information of the protein derived from NMR spectra, and exploits the structural information available from the backbone conformations determined by orientational restraints and a set of discretized side-chain conformations (i.e., rotamers). A Hausdorff

  12. Computing Role Assignments of Proper Interval Graphs in Polynomial Time

    NASA Astrophysics Data System (ADS)

    Heggernes, Pinar; van't Hof, Pim; Paulusma, Daniël

    A homomorphism from a graph G to a graph R is locally surjective if its restriction to the neighborhood of each vertex of G is surjective. Such a homomorphism is also called an R-role assignment of G. Role assignments have applications in distributed computing, social network theory, and topological graph theory. The Role Assignment problem has as input a pair of graphs (G,R) and asks whether G has an R-role assignment. This problem is NP-complete already on input pairs (G,R) where R is a path on three vertices. So far, the only known non-trivial tractable case consists of input pairs (G,R) where G is a tree. We present a polynomial time algorithm that solves Role Assignment on all input pairs (G,R) where G is a proper interval graph. Thus we identify the first graph class other than trees on which the problem is tractable. As a complementary result, we show that the problem is Graph Isomorphism-hard on chordal graphs, a superclass of proper interval graphs and trees.

  13. 21 CFR 1271.27 - Will FDA assign me a registration number?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Will FDA assign me a registration number? 1271.27..., TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Procedures for Registration and Listing § 1271.27 Will FDA assign me a registration number? (a) FDA will assign each location a permanent registration number. (b...

  14. 21 CFR 1271.27 - Will FDA assign me a registration number?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Will FDA assign me a registration number? 1271.27..., TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Procedures for Registration and Listing § 1271.27 Will FDA assign me a registration number? (a) FDA will assign each location a permanent registration number. (b...

  15. 21 CFR 1271.27 - Will FDA assign me a registration number?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Will FDA assign me a registration number? 1271.27..., TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Procedures for Registration and Listing § 1271.27 Will FDA assign me a registration number? (a) FDA will assign each location a permanent registration number. (b...

  16. 21 CFR 1271.27 - Will FDA assign me a registration number?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Will FDA assign me a registration number? 1271.27..., TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Procedures for Registration and Listing § 1271.27 Will FDA assign me a registration number? (a) FDA will assign each location a permanent registration number. (b...

  17. 21 CFR 1271.27 - Will FDA assign me a registration number?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Will FDA assign me a registration number? 1271.27..., TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Procedures for Registration and Listing § 1271.27 Will FDA assign me a registration number? (a) FDA will assign each location a permanent registration number. (b...

  18. Dynamic traffic assignment : genetic algorithms approach

    DOT National Transportation Integrated Search

    1997-01-01

    Real-time route guidance is a promising approach to alleviating congestion on the nations highways. A dynamic traffic assignment model is central to the development of guidance strategies. The artificial intelligence technique of genetic algorithm...

  19. Graduate Writing Assignments across Faculties in a Canadian University

    ERIC Educational Resources Information Center

    Shi, Ling; Dong, Yanning

    2015-01-01

    This study examines 143 graduate assignments across 12 faculties or schools in a Canadian university in order to identify types of writing tasks. Based on the descriptions provided by the instructors, we identified nine types of assignments, with scholarly essay being the most common, followed by summary and response, literature review, project,…

  20. Individual Assignments and Academic Dishonesty--Exploring the Learning Conundrum

    ERIC Educational Resources Information Center

    Leonard, Valorie; LeBrasseur, Rolland

    2008-01-01

    A survey of university business professors focused on their use of individual assignments in courses and their views on cheating and its impact on student learning. Based on responses from 456 professors (37% response rate) from Ontario, Canada, it was concluded that most faculty believe that individual assignments are effective learning tools and…