Impact of Clean Air Act Regulations on Nitrogen Fate and Transport in Neuse River Basin

EPA Science Inventory

This study investigated impacts of Clean Air Act Amendment (CAAA) NOx emissions regulations on the fate and transport of nitrogen for two watersheds in the Neuse River Basin, North Carolina, USA from 1990 to 2020. The Soil and Water Assessment Tool (SWAT) and the Community Multi-...

77 FR 70796 - Privacy Act of 1974; Retirement of Department of Homeland Security Transportation Security...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-27

... privacy issues, please contact: Jonathan Cantor, (202-343-1717), Acting Chief Privacy Officer, Privacy... DEPARTMENT OF HOMELAND SECURITY Office of the Secretary Privacy Act of 1974; Retirement of Department of Homeland Security Transportation Security Administration System of Records AGENCY: Privacy...

77 FR 70796 - Privacy Act of 1974; Retirement of Department of Homeland Security Transportation Security...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-27

...; email: [email protected] . For privacy issues please contact: Jonathan Cantor, (202-343-1717), Acting... DEPARTMENT OF HOMELAND SECURITY Office of the Secretary Privacy Act of 1974; Retirement of Department of Homeland Security Transportation Security Administration System of Records AGENCY: Privacy...

An Affordability Comparison Tool (ACT) for Space Transportation

NASA Technical Reports Server (NTRS)

McCleskey, C. M.; Bollo, T. R.; Garcia, J. L.

2012-01-01

NASA bas recently emphasized the importance of affordability for Commercial Crew Development Program (CCDP), Space Launch Systems (SLS) and Multi-Purpose Crew Vehicle (MPCV). System architects and designers are challenged to come up with architectures and designs that do not bust the budget. This paper describes the Affordability Comparison Tool (ACT) analyzes different systems or architecture configurations for affordability that allows for a comparison of: total life cycle cost; annual recurring costs, affordability figures-of-merit, such as cost per pound, cost per seat, and cost per flight, as well as productivity measures, such as payload throughput. Although ACT is not a deterministic model, the paper develops algorithms and parametric factors that use characteristics of the architectures or systems being compared to produce important system outcomes (figures-of-merit). Example applications of outcome figures-of-merit are also documented to provide the designer with information on the relative affordability and productivity of different space transportation applications.

Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project. ACT/Control/Guidance System study, volume 1

NASA Technical Reports Server (NTRS)

1982-01-01

The active control technology (ACT) control/guidance system task of the integrated application of active controls (IAAC) technology project within the NASA energy efficient transport program was documented. The air traffic environment of navigation and air traffic control systems and procedures were extrapolated. An approach to listing flight functions which will be performed by systems and crew of an ACT configured airplane of the 1990s, and a determination of function criticalities to safety of flight, are the basis of candidate integrated ACT/Control/Guidance System architecture. The system mechanizes five active control functions: pitch augmented stability, angle of attack limiting, lateral/directional augmented stability, gust load alleviation, and maneuver load control. The scope and requirements of a program for simulating the integrated ACT avionics and flight deck system, with pilot in the loop, are defined, system and crew interface elements are simulated, and mechanization is recommended. Relationships between system design and crew roles and procedures are evaluated.

Integrated application of active controls (IAAC) technology to an advanced subsonic transport project. Initial ACT configuration design study

NASA Technical Reports Server (NTRS)

1980-01-01

The initial ACT configuration design task of the integrated application of active controls (IAAC) technology project within the Energy Efficient Transport Program is summarized. A constrained application of active controls technology (ACT) resulted in significant improvements over a conventional baseline configuration previously established. The configuration uses the same levels of technology, takeoff gross weight, payload, and design requirements/objectives as the baseline, except for flying qualities, flutter, and ACT. The baseline wing is moved forward 1.68 m. The configuration incorporates pitch-augmented stability (which enabled an approximately 10% aft shift in cruise center of gravity and a 45% reduction in horizontal tail size), lateral/directional-augmented stability, an angle of attack limiter, wing load alleviation, and flutter mode control. This resulted in a 930 kg reduction in airplane operating empty weight and a 3.6% improvement in cruise efficiency, yielding a 13% range increase. Adjusted to the 3590 km baseline mission range, this amounts to 6% block fuel reduction and a 15.7% higher incremental return on investment, using 1978 dollars and fuel cost.

Vehicle Emission Inspection and Maintenance (I/M) Provision in the Fixing America’s Surface Transportation (FAST) Act

EPA Pesticide Factsheets

This document is a memorandum regarding Vehicle Emission Inspection and Maintenance (I/M) Provision in Fixing America's Surface Transportation (FAST) Act, which provides long-term funding certainty for surface transportation infrastructure planning

Multiple cis-acting signals, some weak by necessity, collectively direct robust transport of oskar mRNA to the oocyte.

PubMed

Ryu, Young Hee; Kenny, Andrew; Gim, Youme; Snee, Mark; Macdonald, Paul M

2017-09-15

Localization of mRNAs can involve multiple steps, each with its own cis -acting localization signals and transport factors. How is the transition between different steps orchestrated? We show that the initial step in localization of Drosophila oskar mRNA - transport from nurse cells to the oocyte - relies on multiple cis -acting signals. Some of these are binding sites for the translational control factor Bruno, suggesting that Bruno plays an additional role in mRNA transport. Although transport of oskar mRNA is essential and robust, the localization activity of individual transport signals is weak. Notably, increasing the strength of individual transport signals, or adding a strong transport signal, disrupts the later stages of oskar mRNA localization. We propose that the oskar transport signals are weak by necessity; their weakness facilitates transfer of the oskar mRNA from the oocyte transport machinery to the machinery for posterior localization. © 2017. Published by The Company of Biologists Ltd.

Virginia Department of Transportation compliance with Section 106 of the National Historic Preservation Act.

DOT National Transportation Integrated Search

1988-01-01

Whenever a highway construction project is federally assisted, Section 106 of the National Historic Preservation Act, in effect, requires the Virginia Department of Transportation (VDOT) to locate and evaluate historic and prehistoric properties with...

Flavonoids act as negative regulators of auxin transport in vivo in arabidopsis

NASA Technical Reports Server (NTRS)

Brown, D. E.; Rashotte, A. M.; Murphy, A. S.; Normanly, J.; Tague, B. W.; Peer, W. A.; Taiz, L.; Muday, G. K.

2001-01-01

Polar transport of the plant hormone auxin controls many aspects of plant growth and development. A number of synthetic compounds have been shown to block the process of auxin transport by inhibition of the auxin efflux carrier complex. These synthetic auxin transport inhibitors may act by mimicking endogenous molecules. Flavonoids, a class of secondary plant metabolic compounds, have been suggested to be auxin transport inhibitors based on their in vitro activity. The hypothesis that flavonoids regulate auxin transport in vivo was tested in Arabidopsis by comparing wild-type (WT) and transparent testa (tt4) plants with a mutation in the gene encoding the first enzyme in flavonoid biosynthesis, chalcone synthase. In a comparison between tt4 and WT plants, phenotypic differences were observed, including three times as many secondary inflorescence stems, reduced plant height, decreased stem diameter, and increased secondary root development. Growth of WT Arabidopsis plants on naringenin, a biosynthetic precursor to those flavonoids with auxin transport inhibitor activity in vitro, leads to a reduction in root growth and gravitropism, similar to the effects of synthetic auxin transport inhibitors. Analyses of auxin transport in the inflorescence and hypocotyl of independent tt4 alleles indicate that auxin transport is elevated in plants with a tt4 mutation. In hypocotyls of tt4, this elevated transport is reversed when flavonoids are synthesized by growth of plants on the flavonoid precursor, naringenin. These results are consistent with a role for flavonoids as endogenous regulators of auxin transport.

A summary : transportation programs and provisions of the Clean Air Act Amendments of 1990

DOT National Transportation Integrated Search

1992-01-01

To achieve the goals of the Clean Air Act Amendments of 1990 (CAAA), State and local officials must first understand the requirements for transportation plans, programs, and projects. The Federal Highway Administration (FHWA) has prepared this brochu...

41 CFR 304-3.8 - Must I adhere to the provisions of the Fly America Act when I receive air transportation to a...

Code of Federal Regulations, 2014 CFR

2014-07-01

... provisions of the Fly America Act when I receive air transportation to a meeting furnished or paid by a non... provisions of the Fly America Act when I receive air transportation to a meeting furnished or paid by a non... reimbursed to your agency by the non-Federal source, the provisions of the Fly America Act do not apply. (See...

41 CFR 304-3.8 - Must I adhere to the provisions of the Fly America Act when I receive air transportation to a...

Code of Federal Regulations, 2012 CFR

2012-07-01

... provisions of the Fly America Act when I receive air transportation to a meeting furnished or paid by a non... provisions of the Fly America Act when I receive air transportation to a meeting furnished or paid by a non... reimbursed to your agency by the non-Federal source, the provisions of the Fly America Act do not apply. (See...

41 CFR 304-3.8 - Must I adhere to the provisions of the Fly America Act when I receive air transportation to a...

Code of Federal Regulations, 2011 CFR

2011-07-01

... provisions of the Fly America Act when I receive air transportation to a meeting furnished or paid by a non... provisions of the Fly America Act when I receive air transportation to a meeting furnished or paid by a non... reimbursed to your agency by the non-Federal source, the provisions of the Fly America Act do not apply. (See...

41 CFR 304-3.8 - Must I adhere to the provisions of the Fly America Act when I receive air transportation to a...

Code of Federal Regulations, 2013 CFR

2013-07-01

... provisions of the Fly America Act when I receive air transportation to a meeting furnished or paid by a non... provisions of the Fly America Act when I receive air transportation to a meeting furnished or paid by a non... reimbursed to your agency by the non-Federal source, the provisions of the Fly America Act do not apply. (See...

State transportation liaison funded positions study

DOT National Transportation Integrated Search

2009-10-01

The Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users (SAFETEA-LU), which was signed into law in August 2005, contained several provisions focused on streamlining the environmental review process. One of these provi...

77 FR 70795 - Privacy Act of 1974; Retirement of Department of Homeland Security Transportation Security...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-27

... 20598-6036; email: [email protected] . For privacy issues please contact: Jonathan Cantor, (202-343... DEPARTMENT OF HOMELAND SECURITY Office of the Secretary Privacy Act of 1974; Retirement of Department of Homeland Security Transportation Security Administration System of Records AGENCY: Privacy...

75 FR 8096 - Privacy Act of 1974; Department of Homeland Security Transportation Security Administration-023...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-23

... Prevention Program System of Records AGENCY: Privacy Office, DHS. ACTION: Notice of Privacy Act system of... to establish a new system of records titled, ``Department of Homeland Security/Transportation Security Administration--023 Workplace Violence Prevention Program System of Records.'' This system will...

75 FR 7978 - Privacy Act of 1974: Implementation of Exemptions; Department of Homeland Security Transportation...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-23

...; Department of Homeland Security Transportation Security Administration-023 Workplace Violence Prevention... Administration-023 Workplace Violence Prevention Program System of Records and this proposed rulemaking. In this... Privacy Act (5 U.S.C. 552a) titled, DHS/TSA-023 Workplace Violence Prevention Program System of Records...

Airborne Measurements in Support of the NASA Atmospheric Carbon and Transport - America (ACT-America) Mission

NASA Technical Reports Server (NTRS)

Meadows, Byron; Davis, Ken; Barrick, John; Browell, Edward; Chen, Gao; Dobler, Jeremy; Fried, Alan; Lauvaux, Thomas; Lin, Bing; McGill, Matt;

Overview of Lidar Contributions to the Atmospheric Carbon and Transport - America (ACT-America) Program

NASA Astrophysics Data System (ADS)

Davis, K. J.; Meadows, B.; Barrick, J. D. W.; Bell, E.; Browell, E. V.; Campbell, J. F.; DiGangi, J. P.; Chen, G.; Dobler, J. T.; Fan, T. F.; Feng, S.; Fried, A.; Kooi, S. A.; Lauvaux, T.; Lin, B.; McGill, M. J.; Miles, N.; Nehrir, A. R.; Obland, M. D.; O'Dell, C.; Pal, S.; Pauly, R.; Sweeney, C.; Yang, M. Y.

2017-12-01

The Atmospheric Carbon and Transport - America (ACT-America) is an Earth Venture Suborbital -2 (EVS-2) mission sponsored by the Earth Science Division of NASA's Science Mission Directorate. A major objective is to enhance our knowledge of the sources/sinks and transport of atmospheric CO2 through the application of remote and in situ airborne measurements of CO2 and other atmospheric properties on spatial and temporal scales not previously available to the science community. ACT-America consists of five campaigns to measure regional carbon and evaluate transport under various meteorological conditions in three regional areas of the Continental United States. Three of the five campaigns, summer 2016, winter 2017, and fall 2017, have taken place. Data have been collected during these campaigns using 2 airborne platforms (NASA Wallops' C-130 and NASA Langley's B-200) with in-situ instruments on both aircraft and three lidar systems on the C-130, along with instrumented towers and coordinated under flights with the Orbiting Carbon Observatory (OCO-2) satellite. The lidar systems include the Harris Corp. Multi-Frequency Fiber Laser Lidar (MFLL), the NASA Langley ASCENDS CarbonHawk Experiment Simulator (ACES) and the Goddard Cloud Physics Laboratory (CPL). The airborne lidars provide unique data that complement the more traditional in situ sensors. Lidar CO2 measurements provide integrated views of spatial variations of partial columns of atmospheric CO2 which can be adjusted to the column of scientific interest by changing flight altitudes. Lidar backscatter data provide detailed views of atmospheric layers, including the atmospheric boundary layer, residual layers, and cloud layers. The combination of these two lidars provide a far more comprehensive view of atmospheric structure and CO2 content than can be achieved with in situ measurements alone. This presentation provides an overview of the application of these three lidar systems toward achieving ACT

41 CFR 304-3.8 - Must I adhere to the provisions of the Fly America Act when I receive air transportation to a...

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false Must I adhere to the provisions of the Fly America Act when I receive air transportation to a meeting furnished or paid by a non... provisions of the Fly America Act when I receive air transportation to a meeting furnished or paid by a non...

Recovery act : states' use of highway infrastructure funds and compliance with the act's requirements.

DOT National Transportation Integrated Search

2009-01-01

The American Recovery and Reinvestment Act of 2009 (Recovery Act) included more than $48 billion for the Department of Transportations (DOT) investment in transportation infrastructure, including highways, rail, and transit. This testimonybased...

Climate Change Adaptation Act : report of the Committee on Commerce, Science, and Transportation on S. 2355

DOT National Transportation Integrated Search

2008-06-05

The Committee on Commerce, Science, and Transportation, to which was referred the bill (S. 2355) to amend the National Climate Program Act to enhance the ability of the United States to : develop and implement climate change adaptation programs and p...

Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Current and advanced act control system definition study

NASA Technical Reports Server (NTRS)

1982-01-01

The Current and Advanced Technology ACT control system definition tasks of the Integrated Application of Active Controls (IAAC) Technology project within the Energy Efficient Transport Program are summarized. The systems mechanize six active control functions: (1) pitch augmented stability; (2) angle of attack limiting; (3) lateral/directional augmented stability; (4) gust load alleviation; (5) maneuver load control; and (6) flutter mode control. The redundant digital control systems meet all function requirements with required reliability and declining weight and cost as advanced technology is introduced.

ADVANCED CUTTINGS TRANSPORT STUDY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stefan Miska; Troy Reed; Ergun Kuru

2004-09-30

The Advanced Cuttings Transport Study (ACTS) was a 5-year JIP project undertaken at the University of Tulsa (TU). The project was sponsored by the U.S. Department of Energy (DOE) and JIP member companies. The objectives of the project were: (1) to develop and construct a new research facility that would allow three-phase (gas, liquid and cuttings) flow experiments under ambient and EPET (elevated pressure and temperature) conditions, and at different angle of inclinations and drill pipe rotation speeds; (2) to conduct experiments and develop a data base for the industry and academia; and (3) to develop mechanistic models for optimizationmore » of drilling hydraulics and cuttings transport. This project consisted of research studies, flow loop construction and instrumentation development. Following a one-year period for basic flow loop construction, a proposal was submitted by TU to the DOE for a five-year project that was organized in such a manner as to provide a logical progression of research experiments as well as additions to the basic flow loop. The flow loop additions and improvements included: (1) elevated temperature capability; (2) two-phase (gas and liquid, foam etc.) capability; (3) cuttings injection and removal system; (4) drill pipe rotation system; and (5) drilling section elevation system. In parallel with the flow loop construction, hydraulics and cuttings transport studies were preformed using drilling foams and aerated muds. In addition, hydraulics and rheology of synthetic drilling fluids were investigated. The studies were performed under ambient and EPET conditions. The effects of temperature and pressure on the hydraulics and cuttings transport were investigated. Mechanistic models were developed to predict frictional pressure loss and cuttings transport in horizontal and near-horizontal configurations. Model predictions were compared with the measured data. Predominantly, model predictions show satisfactory agreements with the measured

A survey of transportation planning practices in state departments of transportation.

DOT National Transportation Integrated Search

1999-03-01

The Intermodal Surface Transportation Efficiency Act (ISTEA), and now its successor the Transportation Equity Act for the 21st Century (TEA-21), fundamentally altered the transportation planning process, providing new opportunities and new challenges...

Liability risk sharing regime for U.S. commercial space transportation : study and analysis

DOT National Transportation Integrated Search

2002-04-01

The Federal Aviation Administration of the Department of Transportation (DOT), in cooperation with interested federal agencies, has performed a study and analysis of seven issues specifically identified in the Space Competitiveness Act, and provides ...

Letter from A & R Transport about Section 308 of the Clean Water Act Discharge of Perfluorinated Compounds

EPA Pesticide Factsheets

January 16, 2009 letter from Kenneth E. Pate, VP of Safety and Risk Management of A & R Transport, Inc. to EPA Clean Water Enforcement Branch, about an Information Request about the Section 308 of the Clean Water Act, discharge of pefluorinated compounds.

Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Final ACT configuration evaluation

NASA Technical Reports Server (NTRS)

1982-01-01

The Final ACT Configuration Evaluation Task of the Integrated Application of Active Controls (IAAC) technology project within the energy efficient transport program is summarized. The Final ACT Configuration, through application of Active Controls Technology (ACT) in combination with increased wing span, exhibits significant performance improvements over the conventional baseline configuration. At the design range for these configurations, 3590 km, the block fuel used is 10% less for the Final ACT Configuration, with significant reductions in fuel usage at all operational ranges. Results of this improved fuel usage and additional system and airframe costs and the complexity required to achieve it were analyzed to determine its economic effects. For a 926 km mission, the incremental return on investment is nearly 25% at 1980 fuel prices. For longer range missions or increased fuel prices, the return is greater. The technical risks encountered in the Final ACT Configuration design and the research and development effort required to reduce these risks to levels acceptable for commercial airplane design are identified.

Secondhand smoke in public places: can Bangalore metropolitan transport corporation be a role model for effective implementation of Cigarette and Other Tobacco Products Act, 2003?

PubMed

Nayak, N S; Annigeri, V B; Revankar, D R; Kenchaigol, S

2010-07-01

The Indian government enacted 'The cigarettes and other tobacco products act, 2003' (COTPA), which prohibits smoking in public places. To validate the efficacy of the Act of 2003, enacted by the Government of India, to prevent secondhand smoking in public places. The study is based on a non-random sample survey of 2,600 bus passengers carried out in the premises of three mega public road transport organizations in Karnataka state, India, in June 2007. The information was gathered through administration of structured schedules. A sample of 1,000 each for the terminus of Bangalore Metropolitan Transport Corporation (BMTC) and Karnataka State Road Transport Corporation (KSRTC) in Bangalore and, 600 for North West Karnataka Road Transport Corporation (NWKRTC) in Hubli-Dharwad city was distributed proportionately according to the number of platforms in each terminus. Simple Averages. There is some reduction in smoking in general as perceived by 69% of the passengers as compared to the scenario a year before the enactment of COTPA. The observed smoking is lower in the bus premises of BMTC where there is strict regulation, and higher in the bus premises of NWKRTC, which has not taken any regulatory measures. Knowing smoking is banned in public places can itself create awareness depending on the coverage extended by media and implementing an agency to reach the public. The implementation of an act depends on the willingness of stakeholders to act upon it. The implementation of COTPA as done by BMTC could well become a role model for replication elsewhere, if BMTC can strive harder to accomplish a 100% smoke-free zone.

Developing a regional approach to transportation demand management and nonmotorized transportation : best practice case studies

DOT National Transportation Integrated Search

1995-01-01

This report is being forwarded to Congress pursuant to Section 6054 (c) of the Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA). The first Implementation Report, transmitted to Congress in June 1994, described the achievements of DOT ...

49 CFR 1016.102 - When the Act applies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 8 2011-10-01 2011-10-01 false When the Act applies. 1016.102 Section 1016.102 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT... BY PARTIES TO BOARD ADJUDICATORY PROCEEDINGS General Provisions § 1016.102 When the Act applies. The...

49 CFR 1016.102 - When the Act applies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 8 2010-10-01 2010-10-01 false When the Act applies. 1016.102 Section 1016.102 Transportation Other Regulations Relating to Transportation (Continued) SURFACE TRANSPORTATION BOARD, DEPARTMENT... BY PARTIES TO BOARD ADJUDICATORY PROCEEDINGS General Provisions § 1016.102 When the Act applies. The...

Maritime security : progress made in implementing Maritime Transportation Security Act, but concerns remain : statement of Margaret Wrightson, Director, Homeland Security and Justice Issues

DOT National Transportation Integrated Search

2003-09-09

After the events of September 11, 2001, concerns were raised over the security of U.S. ports and waterways. In response to the concerns over port security, Congress passed the Maritime Transportation Security Act in November 2002. The act created a b...

Intelligent transportation systems at international borders : a cross-cutting study : facilitating trade and enhancing transportation safety

DOT National Transportation Integrated Search

2001-04-01

The International Border Clearance (IBC) program was initiated under the provisions of the Intermodal Surface Transportation Efficiency Act (ISTEA) of 1991. The program was originally conceived as a means to test the feasibility of utilizing Intellig...

In silico analysis of cis-acting regulatory elements in 5' regulatory regions of sucrose transporter gene families in rice (Oryza sativa Japonica) and Arabidopsis thaliana.

PubMed

Ibraheem, Omodele; Botha, Christiaan E J; Bradley, Graeme

2010-12-01

The regulation of gene expression involves a multifarious regulatory system. Each gene contains a unique combination of cis-acting regulatory sequence elements in the 5' regulatory region that determines its temporal and spatial expression. Cis-acting regulatory elements are essential transcriptional gene regulatory units; they control many biological processes and stress responses. Thus a full understanding of the transcriptional gene regulation system will depend on successful functional analyses of cis-acting elements. Cis-acting regulatory elements present within the 5' regulatory region of the sucrose transporter gene families in rice (Oryza sativa Japonica cultivar-group) and Arabidopsis thaliana, were identified using a bioinformatics approach. The possible cis-acting regulatory elements were predicted by scanning 1.5kbp of 5' regulatory regions of the sucrose transporter genes translational start sites, using Plant CARE, PLACE and Genomatix Matinspector professional databases. Several cis-acting regulatory elements that are associated with plant development, plant hormonal regulation and stress response were identified, and were present in varying frequencies within the 1.5kbp of 5' regulatory region, among which are; A-box, RY, CAT, Pyrimidine-box, Sucrose-box, ABRE, ARF, ERE, GARE, Me-JA, ARE, DRE, GA-motif, GATA, GT-1, MYC, MYB, W-box, and I-box. This result reveals the probable cis-acting regulatory elements that possibly are involved in the expression and regulation of sucrose transporter gene families in rice and Arabidopsis thaliana during cellular development or environmental stress conditions. Copyright © 2010 Elsevier Ltd. All rights reserved.

Can we improve top-down GHG inverse methods through informed prior and better representations of atmospheric transport? Insights from the Atmospheric Carbon and Transport (ACT) - America Aircraft Mission

NASA Astrophysics Data System (ADS)

Feng, S.; Lauvaux, T.; Keller, K.; Davis, K. J.

2016-12-01

Current estimates of biogenic carbon fluxes over North America based on top-down atmospheric inversions are subject to considerable uncertainty. This uncertainty stems to a large part from the uncertain prior fluxes estimates with the associated error covariances and approximations in the atmospheric transport models that link observed carbon dioxide mixing ratios with surface fluxes. Specifically, approximations in the representation of vertical mixing associated with atmospheric turbulence or convective transport and largely under-determined prior fluxes and their error structures significantly hamper our capacity to reliably estimate regional carbon fluxes. The Atmospheric Carbon and Transport - America (ACT-America) mission aims at reducing the uncertainties in inverse fluxes at the regional-scale by deploying airborne and ground-based platforms to characterize atmospheric GHG mixing ratios and the concurrent atmospheric dynamics. Two aircraft measure the 3-dimensional distribution of greenhouse gases at synoptic scales, focusing on the atmospheric boundary layer and the free troposphere during both fair and stormy weather conditions. Here we analyze two main questions: (i) What level of information can we expect from the currently planned observations? (ii) How might ACT-America reduce the hindcast and predictive uncertainty of carbon estimates over North America?

Transportation's role in reducing U.S. greenhouse gas emissions, volume 1 : report to Congress, U.S. Department of Transportation

DOT National Transportation Integrated Search

2010-04-01

This study evaluates potentially viable strategies to reduce transportation : greenhouse gas (GHG) emissions. The study was mandated by the Energy : Independence and Security Act (P.L. 110-140, December 2007). The Act directed : the U.S. Department o...

Transportation's role in reducing U.S. greenhouse gas emissions, volume 2 : report to Congress, U.S. Department of Transportation

DOT National Transportation Integrated Search

2010-04-01

This study evaluates potentially viable strategies to reduce transportation greenhouse gas (GHG) emissions. The study was mandated by the Energy Independence and Security Act (P.L. 110-140, December 2007). The Act directed the U.S. Department of Tran...

Transportation Security Administration Authorization Act

THOMAS, 111th Congress

Rep. Jackson-Lee, Sheila [D-TX-18

2009-04-30

Senate - 06/08/2009 Received in the Senate and Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

Study of negative ion transport phenomena in a plasma source

NASA Astrophysics Data System (ADS)

Riz, D.; Paméla, J.

1996-07-01

NIETZSCHE (Negative Ions Extraction and Transport ZSimulation Code for HydrogEn species) is a negative ion (NI) transport code developed at Cadarache. This code calculates NI trajectories using a 3D Monte-Carlo technique, taking into account the main destruction processes, as well as elastic collisions (H-/H+) and charge exchanges (H-/H0). It determines the extraction probability of a NI created at a given position. According to the simulations, we have seen that in the case of volume production, only NI produced close to the plasma grid (PG) can be extracted. Concerning the surface production, we have studied how NI produced on the PG and accelerated by the plasma sheath backward into the source could be extracted. We demonstrate that elastic collisions and charge exchanges play an important role, which in some conditions dominates the magnetic filter effect, which acts as a magnetic mirror. NI transport in various conditions will be discussed: volume/surface production, high/low plasmas density, tent filter/transverse filter.

Water-quality, water-level, and discharge data associated with the Mississippi embayment agricultural chemical-transport study, 2006-2008

USGS Publications Warehouse

Dalton, Melinda S.; Rose, Claire E.; Coupe, Richard H.

2010-01-01

In 2006, the Agricultural Chemicals: Sources, Transport and Fate study team (Agricultural Chemicals Team, ACT) of the U.S. Geological Survey National Water-Quality Assessment Program began a study in northwestern Mississippi to evaluate the influence of surface-water recharge on the occurrence of agriculturally related nutrients and pesticides in the Mississippi River Valley alluvial aquifer. The ACT study was composed in the Bogue Phalia Basin, an indicator watershed within the National Water-Quality Assessment Program Mississippi Embayment Study Unit and utilized several small, subbasins within the Bogue Phalia to evaluate surface and groundwater interaction and chemical transport in the Basin. Data collected as part of this ACT study include water-quality data from routine and incident-driven water samples evaluated for major ions, nutrients, organic carbon, physical properties, and commonly used pesticides in the area; discharge, gage height and water-level data for surface-water sites, the shallow alluvial aquifer, and hyporheic zone; additionally, agricultural data and detailed management activities were reported by land managers for farms within two subbasins of the Bogue Phalia Basin—Tommie Bayou at Pace, MS, and an unnamed tributary to Clear Creek near Napanee, MS.

Transportation's role in reducing U.S. greenhouse gas emissions, volume 1 and volume 2 : report to Congress, U.S. Department of Transportation

DOT National Transportation Integrated Search

2010-04-01

This study evaluates potentially viable strategies to reduce transportation : greenhouse gas (GHG) emissions. The study was mandated by the Energy : Independence and Security Act (P.L. 110-140, December 2007). The Act directed : the U.S. Department o...

Washington's transportation plan, 1997-2016

DOT National Transportation Integrated Search

1996-04-01

The state's Growth Management Act provides new tools for local governments to plan for growth and the transportation facilities to support that growth. The Clean Air Act mandates transportation efforts to ensure healthy air. The federal Intermodal Su...

23 CFR 710.511 - Transportation enhancements.

Code of Federal Regulations, 2010 CFR

2010-04-01

... transportation funds for transportation enhancement activities (TEA). Transportation enhancement activities which... this section. (b) Requirements. (1) Displacements for TEA are subject to the Uniform Act. (2) Acquisitions for TEA are subject to the Uniform Act except as provided in paragraphs (b)(3), (b)(4), and (b)(5...

77 FR 32178 - Notification of Trails Act Agreement/Substitute Sponsorship

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-31

... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [STB Ex Parte No. 702] Notification of Trails Act Agreement/Substitute Sponsorship AGENCY: Surface Transportation Board. ACTION: Notice of OMB... Trails System Act and Railroad Rights-of-Way, STB Ex Parte No. 702 (STB served Apr. 30, 2012) (77 FR...

Study of negative ion transport phenomena in a plasma source

DOE Office of Scientific and Technical Information (OSTI.GOV)

Riz, D.; Pamela, J.

1996-07-01

NIETZSCHE (Negative Ions Extraction and Transport ZSimulation Code for HydrogEn species) is a negative ion (NI) transport code developed at Cadarache. This code calculates NI trajectories using a 3D Monte-Carlo technique, taking into account the main destruction processes, as well as elastic collisions (H{sup {minus}}/H{sup +}) and charge exchanges (H{sup {minus}}/H{sup 0}). It determines the extraction probability of a NI created at a given position. According to the simulations, we have seen that in the case of volume production, only NI produced close to the plasma grid (PG) can be extracted. Concerning the surface production, we have studied how NImore » produced on the PG and accelerated by the plasma sheath backward into the source could be extracted. We demonstrate that elastic collisions and charge exchanges play an important role, which in some conditions dominates the magnetic filter effect, which acts as a magnetic mirror. NI transport in various conditions will be discussed: volume/surface production, high/low plasmas density, tent filter/transverse filter. {copyright} {ital 1996 American Institute of Physics.}« less

Ergonomic analyses within the French transport and logistics sector: first steps towards a new "act elsewhere" prevention approach.

PubMed

Wioland, Liên

2013-10-01

Statistics from the French Employee National Health Insurance Fund indicate high accident levels in the transport sector. This study represents initial thinking on a new approach to transport sector prevention based on the assumption that a work situation could be improved by acting on another interconnected work situation. Ergonomic analysis of two connected work situations, involving the road haulage drivers and cross-docking platform employees, was performed to test this assumption. Our results show that drivers are exposed to a number of identified risks, but their multiple tasks raise the question of activity intensification. The conditions, under which the drivers will perform their work and take to the road, are partly determined by the quality and organisation of the platform with which they interact. We make a number of recommendations (e.g. changing handling equipment, re-appraising certain jobs) to improve platform organisation and employee working conditions with the aim of also improving driver conditions. These initial steps in this prevention approach appear promising, but more detailed investigation is required. Copyright © 2013 Elsevier Ltd. All rights reserved.

Assessment of GHG models for the surface transportation sector

DOT National Transportation Integrated Search

1993-09-01

The Intermodal Surface Transportation Efficiency Act (ISTEA) of 1991 calls for a study of U.S. international border crossings. The objective of the study is to identify existing and emerging trade corridors and transportation subsystems that facilita...

Amtrak Secure Transportation of Firearms Act

THOMAS, 111th Congress

Sen. Wicker, Roger F. [R-MS

2009-08-06

Senate - 08/06/2009 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Federal Submerged Lands Transportation Development Act

THOMAS, 113th Congress

Sen. Murkowski, Lisa [R-AK

2013-10-29

Senate - 10/29/2013 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Maritime Transportation Security Act of 2010

THOMAS, 111th Congress

Sen. Rockefeller, John D., IV [D-WV

2010-07-22

Senate - 07/22/2010 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Surface Transportation Safety Act of 2011

THOMAS, 112th Congress

Sen. Baucus, Max [D-MT

2011-05-09

Senate - 05/09/2011 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Horse Transportation Safety Act of 2011

THOMAS, 112th Congress

Sen. Kirk, Mark Steven [R-IL

2011-06-27

Senate - 06/27/2011 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Horse Transportation Safety Act of 2013

THOMAS, 113th Congress

Sen. Kirk, Mark Steven [R-IL

2013-08-01

Senate - 08/01/2013 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

State of Montana Department of Transportation 1996-1998 Statewide Transportation Improvement Program

DOT National Transportation Integrated Search

1995-09-01

This is the Statewide Transportation Improvement Program (STIP) developed under : the Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA). The STIP : shows how the funds will be used to accomplish our state's transportation needs : for F...

Bicycle transportation for energy conservation

DOT National Transportation Integrated Search

1980-05-01

The study was mandated by Section 682 of the National Energy Conservation Policy Act of 1978. The study's objectives were to: (1) identify the obstacles to increased bicycle use; (2) develop a Comprehensive Bicycle Transportation Program (CBTP) to ov...

Surface Transportation Savings Act of 2010

THOMAS, 111th Congress

Rep. Perriello, Thomas S.P. [D-VA-5

2010-06-25

Senate - 07/21/2010 Received in the Senate and Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

Transportation Reports Elimination Act of 2014

THOMAS, 113th Congress

Rep. Shuster, Bill [R-PA-9

2013-12-02

Senate - 01/09/2014 Received in the Senate and Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

Hazardous Materials Transportation Act. Hearing before the Subcommittee on Transportation, Tourism, and Hazardous Materials of the Committee on Energy and Commerce, House of Representatives, One Hundredth Congress, First Session, July 30, 1987

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

About 1.5 billion tons of hazardous materials per year are moved in the US by truck, rail, barge, and air. The Hazardous Materials Transportation Act was the first attempt at a comprehensive Federal scheme for regulation. This hearing looks at the Secretary of Transportation's implementation of the statute for oversight and reauthorization responsibilities. Testimony was heard from 16 witnesses, representatives of Chemical Manufacturers Association, the American Trucking Association, the Association of American Railroads, the Department of Transportation, the Environmental Protection Agency, the Environmental Policy Institute, Office of Technology Assessment, Hazardous Materials Advisory Council, National Tank Truck Carriers, Federal Emergency Managementmore » Agency, National Paint and Coatings Association, and a representative from Ohio.« less

75 FR 8139 - Sunshine Act Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-23

... NATIONAL TRANSPORTATION SAFETY BOARD Sunshine Act Meeting TIME AND DATE: 9:30 a.m., Tuesday, March 9, 2010. PLACE: NTSB Conference Center, 429 L'Enfant Plaza, SW., Washington, DC 20594. STATUS: The one item is open to the public. MATTER TO BE CONSIDERED: 7954A Safety Study--Introduction of Glass...

Is Slow-Onset Long-Acting Monoamine Transport Blockade to Cocaine as Methadone is to Heroin? Implication for Anti-Addiction Medications

PubMed Central

Peng, Xiao-Qing; Xi, Zheng-Xiong; Li, Xia; Spiller, Krista; Li, Jie; Chun, Lauren; Wu, Kuo-Ming; Froimowitz, Mark; Gardner, Eliot L

2010-01-01

The success of methadone in treating opiate addiction has suggested that long-acting agonist therapies may be similarly useful for treating cocaine addiction. Here, we examined this hypothesis, using the slow-onset long-acting monoamine reuptake inhibitor 31,345, a trans-aminotetralin analog, in a variety of addiction-related animal models, and compared it with methadone's effects on heroin's actions in the same animal models. Systemic administration of 31,345 produced long-lasting enhancement of electrical brain-stimulation reward (BSR) and extracellular nucleus accumbens (NAc) dopamine (DA). Pretreatment with 31,345 augmented cocaine-enhanced BSR, prolonged cocaine-enhanced NAc DA, and produced a long-term (24-48 h) reduction in cocaine self-administration rate without obvious extinction pattern, suggesting an additive effect of 31,345 with cocaine. In contrast, methadone pretreatment not only dose-dependently inhibited heroin self-administration with an extinction pattern but also dose-dependently inhibited heroin-enhanced BSR and NAc DA, suggesting functional antagonism by methadone of heroin's actions. In addition, 31,345 appears to possess significant abuse liability, as it produces dose-dependent enhancement of BSR and NAc DA, maintains a low rate of self-administration behavior, and dose-dependently reinstates drug-seeking behavior. In contrast, methadone only partially maintains self-administration with an extinction pattern, and fails to induce reinstatement of drug-seeking behavior. These findings suggest that 31,345 is a cocaine-like slow-onset long-acting monoamine transporter inhibitor that may act as an agonist therapy for cocaine addiction. However, its pattern of action appears to be significantly different from that of methadone. Ideal agonist substitutes for cocaine should fully emulate methadone's actions, that is, functionally antagonizing cocaine's action while blocking monoamine transporters to augment synaptic DA. PMID:20827272

Statewide Transportation Needs & Funding Study

DOT National Transportation Integrated Search

1995-05-01

The State Transportation Policy Initiative (STPI)is multi-phase study to examine : current transportation planning, growth management, and transportation funding : practices in Florida and to develop recommendations that can be the basis of : future ...

Pharmacokinetic interplay of phase II metabolism and transport: a theoretical study.

PubMed

Wu, Baojian

2012-01-01

Understanding of the interdependence of cytochrome P450 enzymes and P-glycoprotein in disposition of drugs (also termed "transport-metabolism interplay") has been significantly advanced in recent years. However, whether such "interplay" exists between phase II metabolic enzymes and efflux transporters remains largely unknown. The objective of this article is to explore the role of efflux transporters (acting on the phase II metabolites) in disposition of the parent drug in Caco-2 cells, liver, and intestine via simulations utilizing a catenary model (for Caco-2 system) and physiologically based pharmacokinetic (PBPK) models (for the liver and intestine). In all three models, "transport-metabolism interplay" (i.e., inhibition of metabolite efflux decreases the metabolism) can be observed only when futile recycling (or deconjugation) occurred. Futile recycling appeared to bridge the two processes (i.e., metabolite formation and excretion) and enable the interplay thereof. Without futile recycling, metabolite formation was independent on its downstream process excretion, thus impact of metabolite excretion on its formation was impossible. Moreover, in liver PBPK model with futile recycling, impact of biliary metabolite excretion on the exposure of parent drug [(systemic (reservoir) area under the concentration-time curve (AUC(R1))] was limited; a complete inhibition of efflux resulted in AUC(R1) increases of less than 1-fold only. In intestine PBPK model with futile recycling, even though a complete inhibition of efflux could result in large elevations (e.g., 3.5-6.0-fold) in AUC(R1), an incomplete inhibition of efflux (e.g., with a residual activity of ≥ 20% metabolic clearance) saw negligible increases (<0.9-fold) in AUC(R1). In conclusion, this study presented mechanistic observations of pharmacokinetic interplay between phase II enzymes and efflux transporters. Those studying such "interplay" are encouraged to adequately consider potential consequences of

EFFECTIVENESS OF THE PM 2.5 FEDERAL REFERENCE METHOD TO DIFFERENTIATE FINE AND COARSE MODE AEROSOL (A RESPONSE TO SECTION 6102(E) OF THE TRANSPORTATION EQUITY ACT FOR THE 21ST CENTURY

EPA Science Inventory

This report is submitted in response to Section 6102(e) of the Transportation Equity Act for the 21st Century, which states:

"The Administrator shall conduct a field study of the ability of the PM2.5 Federal Reference Method to differentiate those particles that ...

Physiological responses to repeated transportation of gestating Brahman cows

USDA-ARS?s Scientific Manuscript database

The transportation process acts as a stressor with adverse effects on animal health and performance. The purpose of this study was to examine physiological responses to repeated transportation of gestating Brahman cows, previously classified as mature cows, into temperament groups of calm, moderate,...

Transportation enhancement guidelines : Colorado supplement

DOT National Transportation Integrated Search

2000-10-10

Under the Transportation Equity Act for the 21st Century (TEA-21), the states were given funds to enhance their transportation infrastructures, following basic guidelines set up in the law. The Colorado Department of Transportation (CDOT) developed t...

Transportation Improvement Program of the Mid-Ohio Regional Planning Commission

DOT National Transportation Integrated Search

1996-06-20

The MORPC Transportation Improvement program (TIP) is a staged, multi-year schedule of regionally significant transportation improvements in the Columbus area. The Federal-aid Highway Act of 1962 and the federal Urban Mass Transportation Act of 1964 ...

10 CFR 490.603 - Prohibited acts.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 3 2011-01-01 2011-01-01 false Prohibited acts. 490.603 Section 490.603 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.603 Prohibited acts. It is unlawful for any person to violate any provision of sections 501, 503(b...

10 CFR 490.603 - Prohibited acts.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 3 2013-01-01 2013-01-01 false Prohibited acts. 490.603 Section 490.603 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.603 Prohibited acts. It is unlawful for any person to violate any provision of sections 501, 503(b...

10 CFR 490.603 - Prohibited acts.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 3 2014-01-01 2014-01-01 false Prohibited acts. 490.603 Section 490.603 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.603 Prohibited acts. It is unlawful for any person to violate any provision of sections 501, 503(b...

10 CFR 490.603 - Prohibited acts.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Prohibited acts. 490.603 Section 490.603 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.603 Prohibited acts. It is unlawful for any person to violate any provision of sections 501, 503(b...

10 CFR 490.603 - Prohibited acts.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 3 2012-01-01 2012-01-01 false Prohibited acts. 490.603 Section 490.603 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Investigations and Enforcement § 490.603 Prohibited acts. It is unlawful for any person to violate any provision of sections 501, 503(b...

Pharmacokinetic Model of the Transport of Fast-Acting Insulin From the Subcutaneous and Intradermal Spaces to Blood.

PubMed

Lv, Dayu; Kulkarni, Sandip D; Chan, Alice; Keith, Stephen; Pettis, Ron; Kovatchev, Boris P; Farhi, Leon S; Breton, Marc D

2015-07-01

Pharmacokinetic (PK) models describing the transport of insulin from the injection site to blood assist clinical decision making and are part of in silico platforms for developing and testing of insulin delivery strategies for treatment of patients with diabetes. The ability of these models to accurately describe all facets of the in vivo insulin transport is therefore critical for their application. Here, we propose a new model of fast-acting insulin analogs transport from the subcutaneous and intradermal spaces to blood that can accommodate clinically observed biphasic appearance and delayed clearance of injected insulin, 2 phenomena that are not captured by existing PK models. To develop the model we compare 9 insulin transport PK models which describe hypothetical insulin delivery pathways potentially capable of approximating biphasic appearance of exogenous insulin. The models are tested with respect to their ability to describe clinical data from 10 healthy volunteers which received 1 subcutaneous and 2 intradermal insulin injections on 3 different occasions. The optimal model, selected based on information and posterior identifiability criteria, assumes that insulin is delivered at the administrative site and is then transported to the bloodstream via 2 independent routes (1) diffusion-like process to the blood and (2) combination of diffusion-like processes followed by an additional compartment before entering the blood. This optimal model accounts for biphasic appearance and delayed clearance of exogenous insulin. It agrees better with the clinical data as compared to commonly used models and is expected to improve the in silico development and testing of insulin treatment strategies, including artificial pancreas systems. © 2015 Diabetes Technology Society.

Transportation Enhancements: Status of the $2.4 Billion Authorized for Nonmotorized Transportation

DOT National Transportation Integrated Search

1996-07-01

At least 10% of the $24 billion, 6-year authorization in the Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA) that created the surface transportation program was required to be set aside exclusively for 10 categories of "transportatio...

23 CFR 633.211 - Implementation of the Clean Air Act and the Federal Water Pollution Control Act.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Implementation of the Clean Air Act and the Federal Water Pollution Control Act. 633.211 Section 633.211 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS REQUIRED CONTRACT PROVISIONS Federal-Aid Contracts (Appalachian Contracts) § 633.211...

Surface Transportation Board Reauthorization Act of 2011

THOMAS, 112th Congress

Sen. Rockefeller, John D., IV [D-WV

2011-01-25

Senate - 01/25/2011 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Pipeline Transportation Safety Improvement Act of 2010

THOMAS, 111th Congress

Sen. Lautenberg, Frank R. [D-NJ

2010-09-28

Senate - 09/28/2010 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Transportation Infrastructure Grants and Economic Reinvestment Act

THOMAS, 112th Congress

Sen. Murray, Patty [D-WA

2011-05-10

Senate - 05/10/2011 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Protecting Taxpayers in Transportation Asset Transfers Act

THOMAS, 112th Congress

Sen. Durbin, Richard J. [D-IL

2011-06-16

Senate - 06/16/2011 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

22 CFR 228.21 - Ocean transportation.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Ocean transportation. 228.21 Section 228.21... for USAID Financing § 228.21 Ocean transportation. (a) The Cargo Preference Act of 1954, Section 901(b)(1) of the Merchant Marine Act of 1936, as amended, 46 U.S.C. 1241(b)(1), is applicable to ocean...

RECOVERY ACT - Thylakoid Assembly and Folded Protein Transport by the Tat Pathway

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dabney-Smith, Carole

Assembly of functional photosystems complete with necessary intrinsic (membrane-bound) and extrinsic proteins requires the function of at least 3 protein transport pathways in thylakoid membranes. Our research focuses on one of those pathways, a unique and essential protein transport pathway found in the chloroplasts of plants, bacteria, and some archaebacteria, the Twin arginine translocation (Tat) system. The chloroplast Tat (cpTat) system is thought to be responsible for the proper location of ~50% of thylakoid lumen proteins, several of which are necessary for proper photosystem assembly, maintenance, and function. Specifically, cpTat systems are unique because they transport fully folded and assembledmore » proteins across ion tight membranes using only three membrane components, Tha4, Hcf106, and cpTatC, and the protonmotive force generated by photosynthesis. Despite the importance of the cpTat system in plants, the mechanism of transport of a folded precursor is not well known. Our long-term goal is to investigate the role protein transport systems have on organelle biogenesis, particularly the assembly of membrane protein complexes in thylakoids of chloroplasts. The objective of this proposal is to correlate structural changes in the membrane-bound cpTat component, Tha4, to the mechanism of translocation of folded-precursor substrates across the membrane bilayer by using a cysteine accessibility and crosslinking approach. Our central hypothesis is that the precursor passes through a proteinaceous pore of assembled Tha4 protomers that have undergone a conformational or topological change in response to transport. This research is predicated upon the observations that Tha4 exists in molar excess in the membrane relative to the other cpTat components; its regulated assembly to the precursor-bound receptor; and our data showing oligomerization of Tha4 into very large complexes in response to transport. Our rationale for these studies is that understanding cp

Energy transport corridors: the potential role of Federal lands in states identified by the Energy Policy Act of 2005, section 368(b).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krummel, J.; Hlohowskyj, I.; Kuiper, J.

2011-09-01

Section 106 of the National Historic Preservation Act (NHPA). Under Section 368, Congress divided the United States into two groups of states: the 11 contiguous western states and the remaining states. Direction for energy transportation corridor analysis and selection in the 11 western states was addressed in Section 368(a) of EPAct, while direction for energy transportation corridor analysis and selection in all other states was addressed under Section 368(b) of EPAct. It was clearly the priority of Congress to conduct corridor location studies and designation first on federal lands in the western states. Under Section 368(a), the Agencies produced a programmatic environmental impact statement (EIS), Designation of Energy Corridors on Federal Land in the 11 Western States (DOE and DOI 2008), that was used in part as the basis for designating more than 6,000 mi (9,656 km) of energy transportation corridors on federal land in 11 western states. Under Section 368(a) of EPAct, Congress clearly stated the Agencies needed to (1) designate energy transportation corridors on federal land, (2) conduct the necessary environmental review of the designated corridors, and (3) incorporate the designated corridors into the appropriate land use plans. Congressional direction under Section 368(b) of EPAct differs from that provided under Section 368(a). Specifically, Section 368(b) requires the secretaries of the Agencies, in consultation with the Federal Energy Regulatory Commission (FERC), affected utility industries, and other interested persons, to jointly: (1) Identify corridors for oil, gas, and hydrogen pipelines and electricity transmission and distribution facilities on federal land in states other than the 11 western states identified under Section 368(a) of EPAct, and (2) Schedule prompt action to identify, designate, and incorporate the corridors into the applicable land use plans. While Section 368(a) clearly directs designation as a necessary first step for energy

Intestinal transport: studies with isolated epithelial cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kimmich, G.A.

1979-12-01

Isolated intestinal epithelial cells have been extremely useful for characterizing the nature of intestinal absorption processes and for providing insight into the energetics of Na/sup +/-dependent transport systems. This report describes a number of experimental approaches which have been used for investigating the specific epithelial transport systems involved in sugar absorption, but provides information which ultimately should prove useful for characterizing a number of different intestinal transport events. Similar experiments should also prove useful for exploring the effect of environmental agents on the function of intestinal tissue. In the case of sugars, net absorption is accomplished via a mucosal, Na/supmore » +/-dependent concentrative transport system acting in sequence with a passive serosal system which does not require Na/sup +/. The serosal system limits the full gradient-forming capability of the muscosal system. Agents such as phloretin or cytochalasin B which inhibit serosal transport allow the cells to establish sugar gradients as high as 70 fold in contrast to 10 to 15 fold gradients observed for control cells. Sevety-fold sugar gradients cannot be explained in terms of the energy available in the electrochemical potential for Na/sup +/ if the Na/sub 2/: sugar coupling stoichiometry is 1:1 as commonly assumed. New information indicates that the true Na/sup +/:sugar stoichiometry is in fact 2:1. Flow of two Na/sup +/ ions per sugar molecule down the transmembrane electrochemical potential for Na/sup +/ provides more than sufficient energy to account for observed 70 fold sugar gradients. If flow of sugar by other routes could be completely inhibited, theoretical sugar gradients as high as 400 could be achieved assuming that the cells maintain a membrane potential of -36 mV as measured for intact tissue.« less

The ACT Vision Mission Study Simulation Effort

NASA Astrophysics Data System (ADS)

Wunderer, C. B.; Kippen, R. M.; Bloser, P. F.; Boggs, S. E.; McConnell, M. L.; Hoover, A.; Oberlack, U.; Sturner, S.; Tournear, D.; Weidenspointner, G.; Zoglauer, A.

2004-12-01

The Advanced Compton Telescope (ACT) has been selected by NASA for a one-year "Vision Mission" study. The main goal of this study is to determine feasible instrument configurations to achieve ACT's sensitivity requirements, and to give recommendations for technology development. Space-based instruments operating in the energy range of nuclear lines are subject to complex backgrounds generated by cosmic-ray interactions and diffuse gamma rays; typically measurements are significantly background-dominated. Therefore accurate, detailed simulations of the background induced in different ACT configurations, and exploration of event selection and reconstruction techniques for reducing these backgrounds, are crucial to determining both the capabilities of a given instrument configuration and the technology enhancements that would result in the most significant performance improvements. The ACT Simulation team has assembled a complete suite of tools that allows the generation of particle backgrounds for a given orbit (based on CREME96), their propagation through any instrument and spacecraft geometry (using MGGPOD) - including delayed photon emission from instrument activation - as well as the event selection and reconstruction of Compton-scatter events in the given detectors (MEGAlib). The package can deal with polarized photon beams as well as e.g. anticoincidence shields. We will report on the progress of the ACT simulation effort and the suite of tools used. We thank Elena Novikova at NRL for her contributions, and NASA for support of this research.

Surface Transportation Board Reauthorization Act of 2014

THOMAS, 113th Congress

Sen. Rockefeller, John D., IV [D-WV

2014-09-08

Senate - 12/12/2014 By Senator Rockefeller from Committee on Commerce, Science, and Transportation filed written report. Report No. 113-321. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Surface Transportation Board Reauthorization Act of 2009

THOMAS, 111th Congress

Sen. Rockefeller, John D., IV [D-WV

2009-12-16

Senate - 12/21/2010 By Senator Rockefeller from Committee on Commerce, Science, and Transportation filed written report. Report No. 111-380. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Essential Transportation Worker Identification Credential Assessment Act

THOMAS, 113th Congress

Rep. Jackson Lee, Sheila [D-TX-18

2013-09-27

Senate - 07/29/2014 Received in the Senate and Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

1997 status of the nation's surface transportation system : condition and performance : a summary

DOT National Transportation Integrated Search

1993-09-01

The Intermodal Surface Transportation Efficiency Act (ISTEA) of 1991 calls for a study of U.S. international border crossings. The objective of the study is to identify existing and emerging trade corridors and transportation subsystems that facilita...

State transportation improvement program

DOT National Transportation Integrated Search

1996-07-01

In accordance with 23 U.S.C. Section 135 as amended by the Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA), all highway, bikeway, and transit projects in the state funded under Title 23 and the Federal Transit Act must be included in...

Statewide Transportation Improvement Program (STIP)

DOT National Transportation Integrated Search

1995-02-01

West Virginia's Statewide Transportation Improvement Program (STIP) is designed to meet the requirements outlined in the Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA), and the Statewide Planning; Metropolitan Planning; Rule (23 CFR...

76 FR 2748 - Advisory Council on Transportation Statistics; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-14

... Transportation Statistics; Notice of Meeting AGENCY: Research Innovative Technology Administration, U.S... on Transportation Statistics (ACTS). The meeting will be held on Thursday, February 24, 2011, from 9... establish an Advisory Council on Transportation Statistics subject to the Federal Advisory Committee Act (5...

76 FR 50539 - Advisory Council on Transportation Statistics; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-15

... Transportation Statistics; Notice of Meeting AGENCY: Research and Innovative, Technology Administration, U.S... on Transportation Statistics (ACTS). The meeting will be held on Wednesday, September 28, 2011, from... establish an Advisory Council on Transportation Statistics subject to the Federal Advisory Committee Act (5...

Pragmatic Study of Directive Speech Acts in Stories in Alquran

ERIC Educational Resources Information Center

Santosa, Rochmat Budi; Nurkamto, Joko; Baidan, Nashruddin; Sumarlam

2016-01-01

This study aims at describing the directive speech acts in the verses that contain the stories in the Qur'an. Specifically, the objectives of this study are to assess the sub directive speech acts contained in the verses of the stories and the dominant directive speech acts. The research target is the verses ("ayat") containing stories…

ADVANCED CUTTINGS TRANSPORT STUDY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stefan Miska; Nicholas Takach; Kaveh Ashenayi

2004-07-31

We have tested the loop elevation system. We raised the mast to approximately 25 to 30 degrees from horizontal. All went well. However, while lowering the mast, it moved laterally a couple of degrees. Upon visual inspection, severe spalling of the concrete on the face of the support pillar, and deformation of the steel support structure was observed. At this time, the facility is ready for testing in the horizontal position. A new air compressor has been received and set in place for the ACTS test loop. A new laboratory has been built near the ACTS test loop Roughened cupsmore » and rotors for the viscometer (RS300) were obtained. Rheologies of aqueous foams were measured using three different cup-rotor assemblies that have different surface roughness. The relationship between surface roughness and foam rheology was investigated. Re-calibration of nuclear densitometers has been finished. The re-calibration was also performed with 1% surfactant foam. A new cuttings injection system was installed at the bottom of the injection tower. It replaced the previous injection auger. A mechanistic model for cuttings transport with aerated mud has been developed. Cuttings transport mechanisms with aerated water at various conditions were experimentally investigated. A total of 39 tests were performed. Comparisons between the model predictions and experimental measurements show a satisfactory agreement. Results from the ultrasonic monitoring system indicated that we could distinguish between different sand levels. We also have devised ways to achieve consistency of performance by securing the sensors in the caps in exactly the same manner as long as the sensors are not removed from the caps. A preliminary test was conducted on the main flow loop at 100 gpm flow rate and 20 lb/min cuttings injection rate. The measured bed thickness using the ultrasonic method showed a satisfactory agreement with nuclear densitometer readings. Thirty different data points were collected after

UNC-16 (JIP3) Acts Through Synapse-Assembly Proteins to Inhibit the Active Transport of Cell Soma Organelles to Caenorhabditis elegans Motor Neuron Axons

PubMed Central

Edwards, Stacey L.; Morrison, Logan M.; Yorks, Rosalina M.; Hoover, Christopher M.; Boominathan, Soorajnath; Miller, Kenneth G.

2015-01-01

The conserved protein UNC-16 (JIP3) inhibits the active transport of some cell soma organelles, such as lysosomes, early endosomes, and Golgi, to the synaptic region of axons. However, little is known about UNC-16’s organelle transport regulatory function, which is distinct from its Kinesin-1 adaptor function. We used an unc-16 suppressor screen in Caenorhabditis elegans to discover that UNC-16 acts through CDK-5 (Cdk5) and two conserved synapse assembly proteins: SAD-1 (SAD-A Kinase), and SYD-2 (Liprin-α). Genetic analysis of all combinations of double and triple mutants in unc-16(+) and unc-16(−) backgrounds showed that the three proteins (CDK-5, SAD-1, and SYD-2) are all part of the same organelle transport regulatory system, which we named the CSS system based on its founder proteins. Further genetic analysis revealed roles for SYD-1 (another synapse assembly protein) and STRADα (a SAD-1-interacting protein) in the CSS system. In an unc-16(−) background, loss of the CSS system improved the sluggish locomotion of unc-16 mutants, inhibited axonal lysosome accumulation, and led to the dynein-dependent accumulation of lysosomes in dendrites. Time-lapse imaging of lysosomes in CSS system mutants in unc-16(+) and unc-16(−) backgrounds revealed active transport defects consistent with the steady-state distributions of lysosomes. UNC-16 also uses the CSS system to regulate the distribution of early endosomes in neurons and, to a lesser extent, Golgi. The data reveal a new and unprecedented role for synapse assembly proteins, acting as part of the newly defined CSS system, in mediating UNC-16’s organelle transport regulatory function. PMID:26354976

49 CFR 1105.9 - Coastal Zone Management Act requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 8 2010-10-01 2010-10-01 false Coastal Zone Management Act requirements. 1105.9... ENVIRONMENTAL LAWS § 1105.9 Coastal Zone Management Act requirements. (a) If the proposed action affects land or water uses within a State coastal zone designated pursuant to the Coastal Zone Management Act (16 U.S.C...

49 CFR 1105.9 - Coastal Zone Management Act requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 8 2011-10-01 2011-10-01 false Coastal Zone Management Act requirements. 1105.9... ENVIRONMENTAL LAWS § 1105.9 Coastal Zone Management Act requirements. (a) If the proposed action affects land or water uses within a State coastal zone designated pursuant to the Coastal Zone Management Act (16 U.S.C...

Using geographic information science to evaluate legal restrictions on freight transportation routing in disruptive scenarios

DOE PAGES

Fialkoff, Marc R.; Omitaomu, Olufemi A.; Peterson, Steven K.; ...

2016-12-23

Disasters have consequences and freight transportation is not immune from the effects of such disruptions. In the aftermath of disasters, planners and policymakers have to utilize scarce resources and work within legal frameworks to provide recovery for affected citizens and business. As seen with Hurricane Sandy, various observers noted the challenge with freight rerouting due to inoperable infrastructure and legal barriers involved with intermodal freight transportation. This paper focuses on how Geographic Information Systems (GIS); specifically WebTRAGIS (Transportation Routing Analysis GIS), a transportation routing platform developed at Oak Ridge National Laboratory, can be used to evaluate different routing options formore » freight transportation. In the case of freight transportation, the Merchant Marine Act of 1920 (also known as the Jones Act) restricts Short Sea Shipping (SSS) between coastwise points within U.S. territorial waters. This restriction leads to reliance on land-side modes for handling increased freight resulting from cargo diversion. Using Hurricane Sandy and the closure of the Port of New York/New Jersey as a case study, different modal studies were conducted; ultimately highlighting the various routes and provides insight into potential review of modal restrictions such as the Jones Act.« less

Using geographic information science to evaluate legal restrictions on freight transportation routing in disruptive scenarios

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fialkoff, Marc R.; Omitaomu, Olufemi A.; Peterson, Steven K.

Disasters have consequences and freight transportation is not immune from the effects of such disruptions. In the aftermath of disasters, planners and policymakers have to utilize scarce resources and work within legal frameworks to provide recovery for affected citizens and business. As seen with Hurricane Sandy, various observers noted the challenge with freight rerouting due to inoperable infrastructure and legal barriers involved with intermodal freight transportation. This paper focuses on how Geographic Information Systems (GIS); specifically WebTRAGIS (Transportation Routing Analysis GIS), a transportation routing platform developed at Oak Ridge National Laboratory, can be used to evaluate different routing options formore » freight transportation. In the case of freight transportation, the Merchant Marine Act of 1920 (also known as the Jones Act) restricts Short Sea Shipping (SSS) between coastwise points within U.S. territorial waters. This restriction leads to reliance on land-side modes for handling increased freight resulting from cargo diversion. Using Hurricane Sandy and the closure of the Port of New York/New Jersey as a case study, different modal studies were conducted; ultimately highlighting the various routes and provides insight into potential review of modal restrictions such as the Jones Act.« less

77 FR 64375 - Advisory Council on Transportation Statistics; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-19

... Transportation Statistics; Notice of Meeting AGENCY: Research and Innovative Technology Administration (RITA), U... Advisory Council on Transportation Statistics (ACTS). The meeting will be held on Wednesday, December 12... Transportation Statistics subject to the Federal Advisory Committee Act (5 U.S.C., App. 2) to advise the Bureau...

78 FR 66104 - Advisory Council on Transportation Statistics; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-04

... Transportation Statistics; Notice of Meeting AGENCY: Research and Innovative Technology Administration (RITA), U... of the Advisory Council on Transportation Statistics (ACTS). The meeting will be held on Tuesday... Council on Transportation Statistics subject to the Federal Advisory Committee Act (5 U.S.C., App. 2) to...

Designing a Successful Transportation Project: Lessons Learned from the Clean Cities American Recovery and Reinvestment Act Projects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kelly, Kay L.; Singer, Mark R.

The largest source of funding for alternative fuel vehicle and infrastructure projects in the U.S. Department of Energy's Clean Cities program's history came from the American Recovery and Reinvestment Act (Recovery Act). In 2009, the 25 cost-share projects totaled nearly $300 million in federal government investment. This effort included the involvement of 50 Clean Cities coalitions and their nearly 700 stakeholder partners who provided an additional $500 million in matching funds to support projects in their local communities. In total, those 25 projects established 1,380 alternative fueling stations and put more than 9,000 alternative fuel and advanced technology vehicles onmore » the road. Together, these projects displaced 154 million gasoline gallon equivalents (GGE) of petroleum and averted 254,000 tons of greenhouse gas (GHG) emissions, while supporting U.S. energy independence and contributing to regional economic development. During post-project interviews, project leaders consistently cited a number of key components - ranging from technical and logistical factors, to administrative capabilities - for accomplishing an effective and impactful project. This report summarizes the high-level project design and administrative considerations for conducting a successful transportation project.« less

Wood-Washington-Wirt Interstate Planning Commission : transportation improvement program, FY 1997-2000

DOT National Transportation Integrated Search

2001-01-01

The Transportation Improvement Program, or TIP, required under the provisions of Title 23, U. S. C., and the Federal Transit Act, as amended through June 1992, includes projects consistent with the Long Range Transportation Plan for the study area. T...

20 CFR 202.14 - Service incidental to railroad transportation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Service incidental to railroad transportation. 202.14 Section 202.14 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD RETIREMENT ACT EMPLOYERS UNDER THE ACT § 202.14 Service incidental to railroad transportation. An...

18 CFR 284.267 - Intrastate pipeline emergency transportation rates.

Code of Federal Regulations, 2011 CFR

2011-04-01

... ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY OTHER REGULATIONS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Emergency Natural Gas Sale, Transportation, and Exchange...

Fleet Composition of Rail Tank Cars That Transport Flammable Liquids: 2013-2016

DOT National Transportation Integrated Search

2017-09-05

Section 7308 of the Fixing America's Surface Transportation Act (FAST Act; P. L. 114-94; December 4, 2015) requires the U.S. Department of Transportation (DOT) to assemble and collect data on rail tank cars transporting Class 3 flammable liquids (box...

77 FR 10616 - Advisory Council on Transportation Statistics; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-22

... Transportation Statistics; Notice of Meeting AGENCY: Research and Innovative Technology Administration (RITA... on Transportation Statistics (ACTS). The meeting will be held on Tuesday, March 6, from 9 a.m. to 4... Advisory Council on Transportation Statistics subject to the Federal Advisory Committee Act (5 U.S.C. app...

75 FR 54695 - Advisory Council on Transportation Statistics; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-08

... Transportation Statistics; Notice of Meeting AGENCY: Research and Innovative Technology Administration, U.S... on Transportation Statistics (ACTS). The meeting will be held on Friday, October 8, 2010, from 9 a.m... Advisory Council on Transportation Statistics subject to the Federal Advisory Committee Act (5 U.S.C., App...

Transportation Energy Security and Climate Change Mitigation Act of 2007

DOT National Transportation Integrated Search

2008-09-29

The Committee on Transportation and Infrastructure, to whom was referred the bill (H.R. 2701) to strengthen our Nations energy security and mitigate the effects of climate change by promoting energy efficient transportation and public buildings, c...

Molecular basis of essential amino acid transport from studies of insect nutrient amino acid transporters of the SLC6 family (NAT-SLC6)

PubMed Central

Boudko, Dmitri Y.

2012-01-01

Two protein families that represent major components of essential amino acid transport in insects have been identified. They are annotated as the SLC6 and SLC7 families of transporters according to phylogenetic proximity to characterized amino acid transporters (HUGO nomenclature). Members of these families have been identified as important apical and basolateral parts of transepithelial essential amino acid absorption in the metazoan alimentary canal. Synergistically, they play critical physiological roles as essential substrate providers to diverse metabolic processes, including generic protein synthesis. This review briefly clarifies the requirements for amino acid transport and a variety of amino acid transport mechanisms, including the aforementioned families. Further it focuses on the large group of Nutrient Amino acid Transporters (NATs), which comprise a recently identified subfamily of the Neurotransmitter Sodium Symporter family (NSS or SLC6). The first insect NAT, cloned from the caterpillar gut, has a broad substrate spectrum similar to mammalian B0 transporters. Several new NAT-SLC6 members have been characterized in an effort to explore mechanisms for the essential amino acid absorption in model dipteran insects. The identification and functional characterization of new B0-like and narrow specificity transporters of essential amino acids in fruit fly and mosquitoes leads to a fundamentally important insight: that NATs evolved and act together as the integrated active core of a transport network that mediates active alimentary absorption and systemic distribution of essential amino acids. This role of NATs is projected from the most primitive prokaryotes to the most complex metazoan organisms, and represents an interesting platform for unraveling the molecular evolution of amino acid transport and modeling amino acid transport disorders. The comparative study of NATs elucidates important adaptive differences between essential amino acid transportomes

Validation of the Activities of Community Transportation model for individuals with cognitive impairments.

PubMed

Sohlberg, McKay Moore; Fickas, Stephen; Lemoncello, Rik; Hung, Pei-Fang

2009-01-01

To develop a theoretical, functional model of community navigation for individuals with cognitive impairments: the Activities of Community Transportation (ACTs). Iterative design using qualitative methods (i.e. document review, focus groups and observations). Four agencies providing travel training to adults with cognitive impairments in the USA participated in the validation study. A thorough document review and series of focus groups led to the development of a comprehensive model (ACTs Wheels) delineating the requisite steps and skills for community navigation. The model was validated and updated based on observations of 395 actual trips by travellers with navigational challenges from the four participating agencies. Results revealed that the 'ACTs Wheel' models were complete and comprehensive. The 'ACTs Wheels' represent a comprehensive model of the steps needed to navigate to destinations using paratransit and fixed-route public transportation systems for travellers with cognitive impairments. Suggestions are made for future investigations of community transportation for this population.

Linking transportation and air quality planning : implementation of the transportation conformity regulations in 15 nonattainment areas

DOT National Transportation Integrated Search

1999-07-01

The Clean Air Act Amendments (CAAA) of 1990 require far-reaching efforts under the "transportation conformity" regulations to assure that transportation investments in nonattainment and maintenance areas are consistent with state commitments to meet ...

Spin transport in carbon nanotubes bundles: An ab-initio study

NASA Astrophysics Data System (ADS)

Meena, Shweta; Choudhary, Sudhanshu

2017-10-01

First principles investigations are performed on understanding the spin-polarized transport in carbon nanotubes and carbon nanotube bundles consisting of (8 , 0) and (17 , 0) SWCNTs kept in vertical (out-of-plane) arrangement and contacted by two CrO2 Half-Metallic-Ferromagnetic (HMF) electrodes. On comparison of the results for all the structures, it is observed that carbon nanotube bundle consisting of (17 , 0) CNT offers high TMR ∼100% and the transport phenomenon is tunneling, since there are no transmission states near Fermi level. However, in individual (8 , 0) and (17 , 0) CNT the transport is not because of tunneling, since there are significant number of transmission states near Fermi level. High Magneto Resistance (MR) 96% and 99% is observed in individual (8 , 0) and (17 , 0) CNTs respectively. Both TMR and Spin Injection Efficiency η (Spin-Filtration) are higher in (17 , 0) carbon nanotube bundle structure, which is due to carbon nanotube bundle acting as a perfect barrier in vertical (out-of-plane) arrangement resulting in negligible spin-down current (I↓) in both Parallel Configuration (PC) and Antiparallel Configuration (APC).

78 FR 26113 - Advisory Council on Transportation Statistics; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-03

... Transportation Statistics; Notice of Meeting AGENCY: Research and Innovative Technology Administration (RITA), U... Advisory Council on Transportation Statistics (ACTS). The meeting will be held on Monday, June 10 from 8:30... Transportation Statistics subject to the Federal Advisory Committee Act (5 U.S.C., App. 2) to advise the Bureau...

18 CFR 284.3 - Jurisdiction under the Natural Gas Act.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Natural Gas Act. 284.3 Section 284.3 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY OTHER REGULATIONS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND...

18 CFR 284.3 - Jurisdiction under the Natural Gas Act.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Natural Gas Act. 284.3 Section 284.3 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY OTHER REGULATIONS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND...

40 CFR 52.283 - Interstate Transport.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.283 Interstate Transport. (a) Approval. On November 16, 2007, the California Air Resources Board submitted the “Interstate Transport State... Act section 110(a)(2)(D)(i) for the State of California (September 21, 2007)” (“2007 Transport SIP...

40 CFR 52.283 - Interstate Transport.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.283 Interstate Transport. (a) Approval. On November 16, 2007, the California Air Resources Board submitted the “Interstate Transport State... Act section 110(a)(2)(D)(i) for the State of California (September 21, 2007)” (“2007 Transport SIP...

40 CFR 52.283 - Interstate Transport.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.283 Interstate Transport. (a) Approval. On November 16, 2007, the California Air Resources Board submitted the “Interstate Transport State... Act section 110(a)(2)(D)(i) for the State of California (September 21, 2007)” (“2007 Transport SIP...

Flexible funding opportunities for transportation investments

DOT National Transportation Integrated Search

1996-01-01

The Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA) broke significant ground in giving State and local : decisionmakers greater discretion in the use of Federal transportation dollars. In particular, ISTEAs flexible fund : program...

Empirical study on dyad act-degree distribution in some collaboration networks

NASA Astrophysics Data System (ADS)

Chang, Hui; Zhang, Pei-Pei; He, Yue; He, Da-Ren

2006-03-01

We (and cooperators) suggest studying the evolution of the extended collaboration networks by a dyad-act organizing model. The analytic and numeric studies of the model lead to a conclusion that most of the collaboration networks should show a dyad act-degree distribution (how many acts a dyad belongs to) between a power law and an exponential function, which can be described by a shifted power law. We have done an empirical study on dyad act-degree distribution in some collaboration networks. They are: the train networks in China, the bus network of Beijing, and traditional Chinese medical prescription formulation network. The results show good agreement with this conclusion. We also discuss what dyad act-degree implies in these networks and what are the possible applications of the study. The details will be published elsewhere.

Cleansed Data from Transportation Studies and Surveys | Transportation

Science.gov Websites

and search for transportation studies and surveys by name, date, state, agency, survey records, and browse and download all the drive cycle data from different studies, see drive cycle data. Study/Survey Name Year State(s)/Region Data Collection Agency Survey Records Vehicles with Installed GPS

20 CFR 617.28 - Transportation payments.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Transportation payments. 617.28 Section 617... ASSISTANCE FOR WORKERS UNDER THE TRADE ACT OF 1974 Reemployment Services § 617.28 Transportation payments. (a... transportation expenses if the training is outside the commuting area, but may not receive such assistance if...

20 CFR 617.28 - Transportation payments.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 3 2012-04-01 2012-04-01 false Transportation payments. 617.28 Section 617... ASSISTANCE FOR WORKERS UNDER THE TRADE ACT OF 1974 Reemployment Services § 617.28 Transportation payments. (a... transportation expenses if the training is outside the commuting area, but may not receive such assistance if...

20 CFR 617.28 - Transportation payments.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 3 2013-04-01 2013-04-01 false Transportation payments. 617.28 Section 617... ASSISTANCE FOR WORKERS UNDER THE TRADE ACT OF 1974 Reemployment Services § 617.28 Transportation payments. (a... transportation expenses if the training is outside the commuting area, but may not receive such assistance if...

20 CFR 617.28 - Transportation payments.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 3 2014-04-01 2014-04-01 false Transportation payments. 617.28 Section 617... ASSISTANCE FOR WORKERS UNDER THE TRADE ACT OF 1974 Reemployment Services § 617.28 Transportation payments. (a... transportation expenses if the training is outside the commuting area, but may not receive such assistance if...

20 CFR 617.28 - Transportation payments.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Transportation payments. 617.28 Section 617... ASSISTANCE FOR WORKERS UNDER THE TRADE ACT OF 1974 Reemployment Services § 617.28 Transportation payments. (a... transportation expenses if the training is outside the commuting area, but may not receive such assistance if...

Neutral amino acid transport across brain microvessel endothelial cell monolayers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Audus, K.L.; Borchardt, R.T.

1986-03-01

Brain microvessel endothelial cells (BMEC) which form the blood-brain barrier (BBB) possess an amino acid carrier specific for large neutral amino acids (LNAA). The carrier is important for facilitating the delivery of nutrient LNAA's and centrally acting drugs that are LNAA's, to the brain. Bovine BMEC's were isolated and grown up to complete monolayers on regenerated cellulose-membranes in primary culture. To study the transendothelial transport of leucine, the monolayers were placed in a side-by-side diffusion cell, and transport across the monolayers followed with (/sup 3/H)-leucine. The transendothelial transport of leucine in this in vitro model was determined to be bidirectional,more » and time-, temperature-, and concentration-dependent. The transport of leucine was saturable and the apparent K/sub m/ and V/sub max/, 0.18 mM and 6.3 nmol/mg/min, respectively. Other LNAA's, including the centrally acting drugs, ..cap alpha..-methyldopa, L-DOPA, ..cap alpha..-methyl-tyrosine, and baclofen, inhibited leucine transport. The leucine carrier was also found to be stereospecific and not sensitive to inhibitors of active transport. These results are consistent with previous in vitro and in vivo studies. Primary cultures of BMEC's appear to be a potentially important tool for investigating at the cellular level, the transport mechanisms of the BBB.« less

Intelligent transportation systems in the Transportation Equity Act for the 21st century

DOT National Transportation Integrated Search

1999-01-01

This brochure communicates the Federal Highway Administration's (FHWA's) plans for developing important policies that will profoundly impact the way transportation continues to evolve in the United States. It highlights the key Intelligent Transporta...

18 CFR 284.268 - Local distribution company emergency transportation rates.

Code of Federal Regulations, 2011 CFR

2011-04-01

... FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY OTHER REGULATIONS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Emergency Natural Gas Sale, Transportation, and...

22 CFR 228.22 - Air transportation.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Air transportation. 228.22 Section 228.22... § 228.22 Air transportation. The Fly America Act, Title 49 of the United States Code, Subtitle VII, part A, subpart I, Chapter 401, 40118—Government-Financed Air Transportation, is applicable to all...

22 CFR 228.22 - Air transportation.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Air transportation. 228.22 Section 228.22... § 228.22 Air transportation. The Fly America Act, Title 49 of the United States Code, Subtitle VII, part A, subpart I, Chapter 401, 40118—Government-Financed Air Transportation, is applicable to all...

22 CFR 228.22 - Air transportation.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Air transportation. 228.22 Section 228.22... § 228.22 Air transportation. The Fly America Act, Title 49 of the United States Code, Subtitle VII, part A, subpart I, Chapter 401, 40118—Government-Financed Air Transportation, is applicable to all...

National Transportation Safety Board Reauthorization Act of 2010

THOMAS, 111th Congress

Rep. Oberstar, James L. [D-MN-8

2010-03-02

Senate - 09/29/2010 Received in the Senate and Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

Coast Guard and Maritime Transportation Act of 2014

THOMAS, 113th Congress

Rep. Hunter, Duncan D. [R-CA-50

2014-02-06

Senate - 04/02/2014 Received in the Senate and Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

Virtuous acts as practical medical ethics: an empirical study.

PubMed

Little, Miles; Gordon, Jill; Markham, Pippa; Rychetnik, Lucie; Kerridge, Ian

2011-10-01

To examine the nature, scope and significance of virtues in the biographies of medical practitioners and to determine what kind of virtues are at play in their ethical behaviour and reflection. A case study involving 19 medical practitioners associated with the Sydney Medical School, using semi-structured narrative interviews. Narrative data were analysed using dialectical empiricism, constant comparison and iterative reformulation of research questions. Participants represented virtuous acts as centrally important in their moral assessments of both themselves and others. Acts appeared to be contextually virtuous, rather than expressions of stable character traits, and virtue was linked to acts that served to protect or enhance fundamental values attached to ontological security and human flourishing. Virtue ethics, in this sense, was the single most important ethical system for each of the participants. Virtue ethics, construed as the appraisal of acts in contexts of risk, danger or threat to foundational values, emerged as the 'natural' ethical approach for medical practitioners in this case study. Teaching medical ethics to students and graduates alike needs to accommodate the priority attached to virtuous acts. © 2011 Blackwell Publishing Ltd.

Intelligent transportation systems in the Transportation Equity Act for the 21st century

DOT National Transportation Integrated Search

1998-11-01

This brochure communicates the Federal Highway Administration's plans for developing important policies that will profoundly impact the way transportation continues to evolve in the United States. It highlights the key ITS policy provisions in TEA-21...

18 CFR 284.102 - Transportation by interstate pipelines.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Transportation by... RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Certain Transportation by Interstate Pipelines § 284.102 Transportation by...

18 CFR 284.122 - Transportation by intrastate pipelines.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Transportation by... RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Certain Transportation by Intrastate Pipelines § 284.122 Transportation by...

18 CFR 284.122 - Transportation by intrastate pipelines.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Transportation by... RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Certain Transportation by Intrastate Pipelines § 284.122 Transportation by...

18 CFR 284.122 - Transportation by intrastate pipelines.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Transportation by... RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Certain Transportation by Intrastate Pipelines § 284.122 Transportation by...

18 CFR 284.102 - Transportation by interstate pipelines.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Transportation by... RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Certain Transportation by Interstate Pipelines § 284.102 Transportation by...

18 CFR 284.122 - Transportation by intrastate pipelines.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Transportation by... RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Certain Transportation by Intrastate Pipelines § 284.122 Transportation by...

18 CFR 284.102 - Transportation by interstate pipelines.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Transportation by... RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Certain Transportation by Interstate Pipelines § 284.102 Transportation by...

18 CFR 284.102 - Transportation by interstate pipelines.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Transportation by... RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Certain Transportation by Interstate Pipelines § 284.102 Transportation by...

18 CFR 284.102 - Transportation by interstate pipelines.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Transportation by... RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Certain Transportation by Interstate Pipelines § 284.102 Transportation by...

18 CFR 284.122 - Transportation by intrastate pipelines.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Transportation by... RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Certain Transportation by Intrastate Pipelines § 284.122 Transportation by...

42 CFR 9.11 - Animal transport.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Animal transport. 9.11 Section 9.11 Public Health... CHIMPANZEES HELD IN THE FEDERALLY SUPPORTED SANCTUARY SYSTEM § 9.11 Animal transport. The transportation of chimpanzees by surface or air must be in accordance with the requirements set forth in the Animal Welfare Act...

42 CFR 9.11 - Animal transport.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Animal transport. 9.11 Section 9.11 Public Health... CHIMPANZEES HELD IN THE FEDERALLY SUPPORTED SANCTUARY SYSTEM § 9.11 Animal transport. The transportation of chimpanzees by surface or air must be in accordance with the requirements set forth in the Animal Welfare Act...

42 CFR 9.11 - Animal transport.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Animal transport. 9.11 Section 9.11 Public Health... CHIMPANZEES HELD IN THE FEDERALLY SUPPORTED SANCTUARY SYSTEM § 9.11 Animal transport. The transportation of chimpanzees by surface or air must be in accordance with the requirements set forth in the Animal Welfare Act...

42 CFR 9.11 - Animal transport.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Animal transport. 9.11 Section 9.11 Public Health... CHIMPANZEES HELD IN THE FEDERALLY SUPPORTED SANCTUARY SYSTEM § 9.11 Animal transport. The transportation of chimpanzees by surface or air must be in accordance with the requirements set forth in the Animal Welfare Act...

42 CFR 9.11 - Animal transport.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Animal transport. 9.11 Section 9.11 Public Health... CHIMPANZEES HELD IN THE FEDERALLY SUPPORTED SANCTUARY SYSTEM § 9.11 Animal transport. The transportation of chimpanzees by surface or air must be in accordance with the requirements set forth in the Animal Welfare Act...

The effect of drugs acting on cholinoceptors and mucosal chloride on luminal bicarbonate transport by rat caecum under in vitro conditions.

PubMed Central

Canfield, P.; Abdul-Ghaffar, T.

1991-01-01

1. The transport of HCO3- (Jsm) from a HCO3(-)-buffered serosal to an unbuffered mucosal saline solution has been studied in rat caecum in vitro. 2. Carbachol, bethanechol and acetylcholine (ACh) caused a concentration-dependent fall in Jsm with similar maximum effects. 1,1-Dimethyl-4-phenyl-piperazinium iodide (DMPP) also inhibited Jsm but the effect was less than with the other drugs. Maximum cholinoceptor inhibition was less than that obtained with anoxia. 3. Responses were blocked by atropine (10(-5) M) but hexamethonium (2 x 10(-4) M) significantly altered the response only to DMPP. 4. Physostigmine (10(-5) M) shifted the ACh response curve to the left but physostigmine itself caused inhibition of Jsm which was blocked by atropine. 5. Substitution of mucosal Cl- by NO3- reduced Jsm to a similar extent to maximum cholinoceptor effect and abolished responses to bethanecol. Anoxia further reduced Jsm in the presence of NO3-. 6. Mucosal SITS and DIDS (1 mM) reduced Jsm but this was less than the maximum inhibition seen with drugs acting on cholinoceptors or mucosal Cl- removal. Serosal DIDS caused a similar inhibition. 7. We conclude that cholinoceptor agonists inhibit but do not abolish luminal bicarbonate transport by an action on muscarinic receptors. PMID:1884114

18 CFR 284.9 - Interruptible transportation service.

Code of Federal Regulations, 2010 CFR

2010-04-01

... transportation service. 284.9 Section 284.9 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES General Provisions and Conditions § 284.9 Interruptible transportation service. (a...

18 CFR 284.9 - Interruptible transportation service.

Code of Federal Regulations, 2014 CFR

2014-04-01

... transportation service. 284.9 Section 284.9 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES General Provisions and Conditions § 284.9 Interruptible transportation service. (a...

18 CFR 284.9 - Interruptible transportation service.

Code of Federal Regulations, 2011 CFR

2011-04-01

... transportation service. 284.9 Section 284.9 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES General Provisions and Conditions § 284.9 Interruptible transportation service. (a...

18 CFR 284.9 - Interruptible transportation service.

Code of Federal Regulations, 2012 CFR

2012-04-01

... transportation service. 284.9 Section 284.9 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES General Provisions and Conditions § 284.9 Interruptible transportation service. (a...

18 CFR 284.9 - Interruptible transportation service.

Code of Federal Regulations, 2013 CFR

2013-04-01

... transportation service. 284.9 Section 284.9 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES General Provisions and Conditions § 284.9 Interruptible transportation service. (a...

Metropolitan area transportation planning for healthy communities

DOT National Transportation Integrated Search

1997-09-26

Appendix D of the "Implementation of the National Intelligent Transportation Systems Program", a report forwarded to Congress according to Section 6054(c) of the Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA).

Agricultural industries transportation services (AITS) statewide needs assessment study : agriculture worker transportation needs assessment

DOT National Transportation Integrated Search

2003-05-01

The California Department of Transportation (Caltrans) funded the Agricultural Industries Transportation Services Statewide Needs Assessment Study to determine the existence and extent of the unmet transportation needs among the state's agricultural ...

Linking transportation and air quality planning implementation of the transportation conformity regulations in 15 nonattainment areas : executive summary

DOT National Transportation Integrated Search

1999-03-01

Clean Air Act Amendments (CAAA) of 1980 requires far reaching efforts under the "transportation conformity" regulations to assure that transportation investments in non-attainment and maintenance areas are consistent with state commitments to meet na...

Coast Guard and Maritime Transportation Act of 2012

THOMAS, 112th Congress

Rep. LoBiondo, Frank A. [R-NJ-2

2012-06-01

House - 06/07/2012 Subcommittee on Coast Guard and Maritime Transportation Discharged. (All Actions) Notes: For further action, see H.R.2838, which became Public Law 112-213 on 12/20/2012. Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Transportation Air Pollution Studies (TAPS) System

DOT National Transportation Integrated Search

1974-03-01

This report describes the Transportation Air Pollution Studies (TAPS) Data Base and the Software System which has been developed in association with it. : The TAPS Data Base will be used to store the transportation air pollution data (including emiss...

18 CFR 284.7 - Firm transportation service.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Firm transportation... AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES General Provisions and Conditions § 284.7 Firm transportation service. (a) Firm...

18 CFR 284.7 - Firm transportation service.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Firm transportation... AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES General Provisions and Conditions § 284.7 Firm transportation service. (a) Firm...

18 CFR 284.7 - Firm transportation service.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Firm transportation... AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES General Provisions and Conditions § 284.7 Firm transportation service. (a) Firm...

18 CFR 284.7 - Firm transportation service.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Firm transportation... AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES General Provisions and Conditions § 284.7 Firm transportation service. (a) Firm...

75 FR 51074 - Ocean Transportation Intermediary License Applicants

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-18

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Applicants Notice is hereby... Transportation Intermediary (OTI) pursuant to section 19 of the Shipping Act of 1984 as amended (46 U.S.C... Office of Transportation Intermediaries, Federal Maritime Commission, Washington, DC 20573. Advanced...

The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter.

PubMed

Modali, Sita D; Zgurskaya, Helen I

2011-08-01

Escherichia coli MacAB-TolC is a tripartite macrolide efflux transporter driven by hydrolysis of ATP. In this complex, MacA is the periplasmic membrane fusion protein that stimulates the activity of MacB transporter and establishes the link with the outer membrane channel TolC. The molecular mechanism by which MacA stimulates MacB remains unknown. Here, we report that the periplasmic membrane proximal domain of MacA plays a critical role in functional MacA-MacB interactions and stimulation of MacB ATPase activity. Binding of MacA to MacB stabilizes the ATP-bound conformation of MacB, whereas interactions with both MacB and TolC affect the conformation of MacA. A single G353A substitution in the C-terminus of MacA inactivates MacAB-TolC function by changing the conformation of the membrane proximal domain of MacA and disrupting the proper assembly of the MacA-MacB complex. We propose that MacA acts in transport by promoting MacB transition into the closed ATP-bound conformation and in this respect, is similar to the periplasmic solute-binding proteins. © 2011 Blackwell Publishing Ltd.

The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter

PubMed Central

Modali, Sita D.; Zgurskaya, Helen I.

2011-01-01

Escherichia coli MacAB-TolC is a tri-partite macrolide efflux transporter driven by hydrolysis of ATP. In this complex, MacA is the periplasmic membrane fusion protein that stimulates the activity of MacB transporter and establishes the link with the outer membrane channel TolC. The molecular mechanism by which MacA stimulates MacB remains unknown. Here, we report that the periplasmic membrane proximal domain of MacA plays a critical role in functional MacA-MacB interactions and stimulation of MacB ATPase activity. Binding of MacA to MacB stabilizes the ATP-bound conformation of MacB, whereas interactions with both MacB and TolC affect the conformation of MacA. A single G353A substitution in the C-terminus of MacA inactivates MacAB-TolC function by changing the conformation of the membrane proximal domain of MacA and disrupting the proper assembly of the MacA-MacB complex. We propose that MacA acts in transport by promoting MacB transition into the closed ATP-bound conformation and in this respect, is similar to the periplasmic solute-binding proteins. PMID:21696464

Federal Black Lung Benefits Act

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stallsmith, W.P. Jr.

The basis for the filing of a civil action suit brought by a number of railroads against the Secretaries of Labor, Health and Human Services and the Treasury for declaratory and injunctive relief from certain provisions of the Federal Black Lung Benefit Act is set forth. The arguments that railroads are not liable for payment of benefits to their workers under this act hinge on the definition of the words transportation, miners, and coal mines and the intent of Congress when the act was drafted and enacted. It is also argued that benefits are available to railroad employees and theirmore » families under benefit plans other than the Black Lung Benefits Act. The chronology of the legal events surrounding the civil suit is set forth in some detail, and basically the logic of the article is strongly supportive of the railroads' position on the issue. (BLM)« less

Guidelines for development of the Iowa statewide transportation improvement program (STIP). Revised.

DOT National Transportation Integrated Search

2004-01-01

The Transportation Equity Act for the 21st Century (TEA-21) continues the Intermodal Surface Transportation Efficiency Act of 1991's requirement for an extensive, ongoing cooperative planning effort for programming federal funding. Iowa's STIP is dev...

Transporters, channels, or simple diffusion? Dogmas, atypical roles and complexity in transport systems.

PubMed

Conde, Artur; Diallinas, George; Chaumont, François; Chaves, Manuela; Gerós, Hernâni

2010-06-01

The recent breakthrough discoveries of transport systems assigned with atypical functions provide evidence for complexity in membrane transport biochemistry. Some channels are far from being simple pores creating hydrophilic passages for solutes and can, unexpectedly, act as enzymes, or mediate high-affinity uptake, and some transporters are surprisingly able to function as sensors, channels or even enzymes. Furthermore, numerous transport studies have demonstrated complex multiphasic uptake kinetics for organic and mineral nutrients. The biphasic kinetics of glucose uptake in Saccharomyces cerevisiae, a result of several genetically distinct uptake systems operating simultaneously, is a classical example that is a subject of continuous debate. In contrast, some transporters display biphasic kinetics, being bona fidae dual-affinity transporters, their kinetic properties often modulated by post-translational regulation. Also, aquaporins have recently been reported to exhibit diverse transport properties and can behave as highly adapted, multifunctional channels, transporting solutes such as CO(2), hydrogen peroxide, urea, ammonia, glycerol, polyols, carbamides, purines and pyrimidines, metalloids, glycine, and lactic acid, rather than being simple water pores. The present review provides an overview on some atypical functions displayed by transporter proteins and discusses how this novel knowledge on cellular uptake systems may be related to complex multiphasic uptake kinetics often seen in a wide variety of living organisms and the intriguing diffusive uptake of sugars and other solutes. Copyright 2009 Elsevier Ltd. All rights reserved.

High-speed civil transport study

NASA Technical Reports Server (NTRS)

1989-01-01

A system study of the potential for a high-speed commercial transport has addressed technological, economic, and environmental constraints. Market projections indicate a need for fleets of transports with supersonic or greater cruise speeds by the year 2000 to 2005. The associated design requirements called for a vehicle to carry 250 to 300 passengers over a range of 5,000 to 6,000 nautical miles. The study was initially unconstrained in terms of vehicle characteristic, such as cruise speed, propulsion systems, fuels, or structural materials. Analyses led to a focus on the most promising vehicle concepts. These were concepts that used a kerosene-type fuel and cruised at Mach numbers between 2.0 to 3.2. Further systems study identified the impact of environmental constraints (for community noise, sonic boom, and engine emissions) on economic attractiveness and technological needs. Results showed that current technology cannot produce a viable high-speed civil transport; significant advances are required to reduce takeoff gross weight and allow for both economic attractiveness and environmental accepatability. Specific technological requirements were identified to meet these needs.

32 CFR 718.3 - Transportation of dependents.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 5 2011-07-01 2011-07-01 false Transportation of dependents. 718.3 Section 718... PERSONS ACT § 718.3 Transportation of dependents. (a) Whenever a person in active service is officially... and circumstances of the dependents and the destination to which transportation is requested. In the...

32 CFR 718.3 - Transportation of dependents.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 5 2013-07-01 2013-07-01 false Transportation of dependents. 718.3 Section 718... PERSONS ACT § 718.3 Transportation of dependents. (a) Whenever a person in active service is officially... and circumstances of the dependents and the destination to which transportation is requested. In the...

32 CFR 718.3 - Transportation of dependents.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 5 2014-07-01 2014-07-01 false Transportation of dependents. 718.3 Section 718... PERSONS ACT § 718.3 Transportation of dependents. (a) Whenever a person in active service is officially... and circumstances of the dependents and the destination to which transportation is requested. In the...

The Impact of Modifying Jones Act on US Domestic Shipping : Research Project Capsule

DOT National Transportation Integrated Search

2012-09-01

The Jones Act, or Section 27 of the Merchant Marine Act of 1920, relates to goods and passengers : transported by water between US ports, hereafter referred to as domestic shipping or cabotage. : The Jones Act specifi cally mandates that all domestic...

75 FR 76466 - Ocean Transportation Intermediary License Applicants

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-08

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Applicants Notice is hereby... Transportation Intermediary (OTI) pursuant to section 19 of the Shipping Act of 1984 as amended (46 U.S.C... Office of Transportation Intermediaries, Federal Maritime Commission, Washington, DC 20573. CIL Freight...

76 FR 72409 - Ocean Transportation Intermediary License Applicants

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-23

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Applicants Notice is hereby... Transportation Intermediary (OTI) pursuant to section 19 of the Shipping Act of 1984 as amended (46 U.S.C... Office of Transportation Intermediaries, Federal Maritime Commission, Washington, DC 20573, by telephone...

A charging study of ACTS using NASCAP

NASA Technical Reports Server (NTRS)

Herr, Joel L.

1991-01-01

The NASA Charging Analyzer Program (NASCAP) computer code is a three dimensional finite element charging code designed to analyze spacecraft charging in the magnetosphere. Because of the characteristics of this problem, NASCAP can use an quasi-static approach to provide a spacecraft designer with an understanding of how a specific spacecraft will interact with a geomagnetic substorm. The results of the simulation can help designers evaluate the probability and location of arc discharges of charged surfaces on the spacecraft. A charging study of NASA's Advanced Communication Technology Satellite (ACTS) using NASCAP is reported. The results show that the ACTS metalized multilayer insulating blanket design should provide good electrostatic discharge control.

Transportation Infrastructure: FHWA Should Access and Compare the Benefits of Projects When Awarding Discretionary Grants

DOT National Transportation Integrated Search

1999-09-24

The Transportation Equity Act for the 21st Century (TEA-21) required a number of changes to the Department of Transportation's (DOT) process for awarding discretionary grants administered by the FHWA. The act directed the Secretary of Transportation ...

41 CFR 102-117.135 - What are the international transportation restrictions?

Code of Federal Regulations, 2012 CFR

2012-01-01

... 47.5). For example: (a) Arrangements for international air transportation services must follow the Fly America Act (International Air Transportation Fair Competitive Practices Act of 1974) (49 U.S.C. 40118); and (b) International movement of property by water is subject to the cargo preference laws (see...

41 CFR 102-117.135 - What are the international transportation restrictions?

Code of Federal Regulations, 2013 CFR

2013-07-01

... 47.5). For example: (a) Arrangements for international air transportation services must follow the Fly America Act (International Air Transportation Fair Competitive Practices Act of 1974) (49 U.S.C. 40118); and (b) International movement of property by water is subject to the cargo preference laws (see...

41 CFR 102-117.135 - What are the international transportation restrictions?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 47.5). For example: (a) Arrangements for international air transportation services must follow the Fly America Act (International Air Transportation Fair Competitive Practices Act of 1974) (49 U.S.C. 40118); and (b) International movement of property by water is subject to the cargo preference laws (see...

Spatial Data from Transportation Studies and Surveys | Transportation

Science.gov Websites

transportation studies and surveys, submit an application for approval to connect to a restricted secure portal environment. For a list of studies and surveys, see cleansed data. Application Process For accessing spatial data, learn about the application and approval process. If you'd like to apply to access the spatial

77 FR 25910 - National Trails System Act and Railroad Rights-of-Way

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-02

...] National Trails System Act and Railroad Rights-of-Way AGENCY: Surface Transportation Board, DOT. ACTION...) for rail banking and interim trail use under the National Trails System Act (Trails Act). New rules are adopted that require the parties jointly to notify the Board when an interim trail use/rail...

A novel small-molecule thienoquinolin urea transporter inhibitor acts as a potential diuretic.

PubMed

Li, Fei; Lei, Tianluo; Zhu, Juanjuan; Wang, Weiling; Sun, Yi; Chen, Jihui; Dong, Zixun; Zhou, Hong; Yang, Baoxue

2013-06-01

Urea transporters (UTs) are a family of membrane channel proteins that are specifically permeable to urea and play an important role in intrarenal urea recycling and in urine concentration. Using an erythrocyte osmotic lysis assay, we screened a small-molecule library for inhibitors of UT-facilitated urea transport. A novel class of thienoquinolin UT-B inhibitors were identified, of which PU-14 had potent inhibition activity on human, rabbit, rat, and mouse UT-B. The half-maximal inhibitory concentration of PU-14 on rat UT-B-mediated urea transport was ∼0.8 μmol/l, and it did not affect urea transport in mouse erythrocytes lacking UT-B but inhibited UT-A-type urea transporters, with 36% inhibition at 4 μmol/l. PU-14 showed no significant cellular toxicity at concentrations up to its solubility limit of 80 μmol/l. Subcutaneous delivery of PU-14 (at 12.5, 50, and 100 mg/kg) to rats caused an increase of urine output and a decrease of the urine urea concentration and subsequent osmolality without electrolyte disturbances and liver or renal damages. This suggests that PU-14 has a diuretic effect by urea-selective diuresis. Thus, PU-14 or its analogs might be developed as a new diuretic to increase renal fluid clearance in diseases associated with water retention without causing electrolyte imbalance. PU-14 may establish 'chemical knockout' animal models to study the physiological functions of UTs.

National space transportation studies

NASA Technical Reports Server (NTRS)

Durocher, Cort L.; Irby, Thomas M.; Jenkins, James C.; Gorski, Raymond J.

1986-01-01

This paper describes the government and industry activities and findings in response to a Presidential directive to study second-generation space transportation systems. Topics discussed include study purpose, mission needs, architecture development, system concepts, and technology recommendations. Interim study findings will also be presented. The study is being jointly managed by DOD and NASA and equally funded by DOD, NASA, and the Strategic Defense Initiative Organization.

Planning for intelligent transportation systems in small urban areas.

DOT National Transportation Integrated Search

1997-01-01

Intelligent transportation systems (ITS) has been a primary program focus of the U.S. Department of Transportation since its origination in the Intermodal Surface Transportation Efficiency Act of 1991. The federal ITS program funded early deployment ...

18 CFR 367.3920 - Account 392, Transportation equipment.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., Transportation equipment. 367.3920 Section 367.3920 Conservation of Power and Water Resources FEDERAL ENERGY... GAS ACT Service Company Property Chart of Accounts § 367.3920 Account 392, Transportation equipment. (a) This account must include the cost of transportation vehicles used for service company purposes...

18 CFR 367.3920 - Account 392, Transportation equipment.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., Transportation equipment. 367.3920 Section 367.3920 Conservation of Power and Water Resources FEDERAL ENERGY... GAS ACT Service Company Property Chart of Accounts § 367.3920 Account 392, Transportation equipment. (a) This account must include the cost of transportation vehicles used for service company purposes...

18 CFR 367.3920 - Account 392, Transportation equipment.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., Transportation equipment. 367.3920 Section 367.3920 Conservation of Power and Water Resources FEDERAL ENERGY... GAS ACT Service Company Property Chart of Accounts § 367.3920 Account 392, Transportation equipment. (a) This account must include the cost of transportation vehicles used for service company purposes...

A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium

PubMed Central

Slavic, Ksenija; Krishna, Sanjeev; Lahree, Aparajita; Bouyer, Guillaume; Hanson, Kirsten K.; Vera, Iset; Pittman, Jon K.; Staines, Henry M.; Mota, Maria M.

2016-01-01

Iron is an essential micronutrient but is also highly toxic. In yeast and plant cells, a key detoxifying mechanism involves iron sequestration into intracellular storage compartments, mediated by members of the vacuolar iron-transporter (VIT) family of proteins. Here we study the VIT homologue from the malaria parasites Plasmodium falciparum (PfVIT) and Plasmodium berghei (PbVIT). PfVIT-mediated iron transport in a yeast heterologous expression system is saturable (Km∼14.7 μM), and selective for Fe2+ over other divalent cations. PbVIT-deficient P. berghei lines (Pbvit−) show a reduction in parasite load in both liver and blood stages of infection in mice. Moreover, Pbvit− parasites have higher levels of labile iron in blood stages and are more sensitive to increased iron levels in liver stages, when compared with wild-type parasites. Our data are consistent with Plasmodium VITs playing a major role in iron detoxification and, thus, normal development of malaria parasites in their mammalian host. PMID:26786069

A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium.

PubMed

Slavic, Ksenija; Krishna, Sanjeev; Lahree, Aparajita; Bouyer, Guillaume; Hanson, Kirsten K; Vera, Iset; Pittman, Jon K; Staines, Henry M; Mota, Maria M

2016-01-20

Iron is an essential micronutrient but is also highly toxic. In yeast and plant cells, a key detoxifying mechanism involves iron sequestration into intracellular storage compartments, mediated by members of the vacuolar iron-transporter (VIT) family of proteins. Here we study the VIT homologue from the malaria parasites Plasmodium falciparum (PfVIT) and Plasmodium berghei (PbVIT). PfVIT-mediated iron transport in a yeast heterologous expression system is saturable (Km ∼ 14.7 μM), and selective for Fe(2+) over other divalent cations. PbVIT-deficient P. berghei lines (Pbvit(-)) show a reduction in parasite load in both liver and blood stages of infection in mice. Moreover, Pbvit(-) parasites have higher levels of labile iron in blood stages and are more sensitive to increased iron levels in liver stages, when compared with wild-type parasites. Our data are consistent with Plasmodium VITs playing a major role in iron detoxification and, thus, normal development of malaria parasites in their mammalian host.

78 FR 11950 - Advisory Council on Transportation Statistics; Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-20

... Transportation Statistics; Meeting AGENCY: Research and Innovative Technology Administration (RITA), DOT. ACTION...) (Pub. L. 72-363; 5 U.S.C. app. 2), a meeting of the Advisory Council on Transportation Statistics (ACTS... Transportation to establish an Advisory Council on Transportation Statistics subject to the Federal Advisory...

76 FR 8992 - National Trails System Act and Railroad Rights-of-Way

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-16

...] National Trails System Act and Railroad Rights-of-Way AGENCY: Surface Transportation Board, DOT. ACTION... procedures regarding the use of railroad rights-of-way for railbanking and interim trail use under the National Trails System Act (Trails Act). DATES: Comments are due by April 12, 2011; replies are due by May...

Tracking the deployment of the integrated metropolitan intelligent transportation systems infrastructure in The USA : FY99 results

DOT National Transportation Integrated Search

1998-09-16

One of the new requirements of the Intermodal Surface Transportation Efficiency Act of 1991 is the requirement that State Departments of Transportation, Metropolitan Planning Organizations, and transit operators conduct a major investment study (MIS)...

77 FR 64835 - Sunshine Act Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-23

... NUCLEAR REGULATORY COMMISSION Sunshine Act Meeting AGENCY HOLDING THE MEETINGS: Nuclear Regulatory... webcast live at the Web address--www.nrc.gov. 9:30 a.m. Strategic Programmatic Overview of the Spent Fuel Storage and Transportation and Fuel Facilities Business Lines (Public Meeting) (Contact: Kevin Mattern...

78 FR 30258 - Hazardous Materials: Enhanced Enforcement Procedures-Resumption of Transportation

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-22

... 21st Century Act, or the MAP-21, which included the Hazardous Materials Transportation Safety... 6, 2012, the President signed the Moving Ahead for Progress in the 21st Century Act, or the MAP-21... This NPRM In MAP-21 Congress directed the Secretary to address certain transportation matters related...

Perspectives on three issues facing the transportation manager in the nineties. Research report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, C.A.; Marzette, D.; McCoy, B.

1999-03-01

The nineties have been a period of tremendous change for the transportation industry. The Intermodal Surface Transportation Efficiency Act, Clean Air Act Amendments, Americans with Disabilities Act, and increasing gender and ethnic diversity have caused agencies to reassess their standard operating procedures. Greater knowledge has been sought by senior level transportation officials in an effort to prepare agencies for the changing policy, including, seminars and workshops, revisions to policy manuals, and strengthened procedures regarding how issues will be resolved. This research examines the level and nature of direct impacts on the transportation organization. Major legislative changes and mandates have imposedmore » the need for changes in how transportation systems operate. Transportation professionals continue to be challenged to develop plans and implement services that respond to mandates within the framework of the legislation.« less

Federal Surface Transportation Policy and Planning Act of 2009

THOMAS, 111th Congress

Sen. Rockefeller, John D., IV [D-WV

2009-05-14

Senate - 05/14/2009 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Federal Surface Transportation Policy and Planning Act of 2011

THOMAS, 112th Congress

Sen. Rockefeller, John D., IV [D-WV

2011-02-10

Senate - 02/10/2011 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Electron Transport and Nonlinear Optical Properties of Substituted Aryldimesityl Boranes: A DFT Study

PubMed Central

Pandith, Altaf Hussain; Islam, Nasarul

2014-01-01

A comprehensive theoretical study was carried out on a series of aryldimesityl borane (DMB) derivatives using Density Functional theory. Optimized geometries and electronic parameters like electron affinity, reorganization energy, frontiers molecular contours, polarizability and hyperpolarizability have been calculated by employing B3PW91/6-311++G (d, p) level of theory. Our results show that the Hammett function and geometrical parameters correlates well with the reorganization energies and hyperpolarizability for the series of DMB derivatives studied in this work. The orbital energy study reveals that the electron releasing substituents increase the LUMO energies and electron withdrawing substituents decrease the LUMO energies, reflecting the electron transport character of aryldimesityl borane derivatives. From frontier molecular orbitals diagram it is evident that mesityl rings act as the donor, while the phenylene and Boron atom appear as acceptors in these systems. The calculated hyperpolarizability of secondary amine derivative of DMB is 40 times higher than DMB (1). The electronic excitation contributions to the hyperpolarizability studied by using TDDFT calculation shows that hyperpolarizability correlates well with dipole moment in ground and excited state and excitation energy in terms of the two-level model. Thus the results of these calculations can be helpful in designing the DMB derivatives for efficient electron transport and nonlinear optical material by appropriate substitution with electron releasing or withdrawing substituents on phenyl ring of DMB system. PMID:25479382

Petersburg National Battlefield : alternative transportation feasibility study

DOT National Transportation Integrated Search

2012-11-13

This report studies the feasibility of alternative solutions to several transportation problems affecting Petersburg National Battlefield in Petersburg, Virginia. Current transportation problems include site-specific access issues, wayfinding and nav...

Rules, Roles, and Responsibilities in Transportation Planning and Air Quality: One State's View

DOT National Transportation Integrated Search

1999-01-01

The Clean Air Act Amendments (CAAA) of 1990 and the Intermodal Surface : Transportation Efficiency Act (ISTEA) of 1991 are a pivotal moment in : transportation planning in the United States. In 1997 the U.S. Environmental : Protection Agency revised ...

Graduate course development : transportation policy and politics.

DOT National Transportation Integrated Search

2009-08-01

Transportation, public policy, and politics are inextricably linked and have been, in the United States, from : at least 1956, with the birth of the federal highway system and the Interstate Highway Act, if not earlier. : Much of the transportation s...

Transporting Handicapped Students: A Resource Manual and Recommended Guidelines for School Transportation and Special Education Personnel.

ERIC Educational Resources Information Center

Bluth, Linda Fran

The manual is intended to recommend policy guidelines for special educators and transporters of handicapped students. Beginning with a review of the requirements of P.L. 94-142 (The Education for All Handicapped Children Act) and a discussion of transportation as a related service provided to handicapped students, the manual proceeds to…

Alternative transportation study : Wichita Mountains Wildlife Refuge

DOT National Transportation Integrated Search

2010-08-01

This report provides an assessment of historic and current visitation, infrastructure, and transportation conditions at the Wichita Mountains Wildlife Refuge and surrounding areas in southwest Oklahoma. The study defines transportation-related goals ...

Dendritic transport of tick-borne flavivirus RNA by neuronal granules affects development of neurological disease.

PubMed

Hirano, Minato; Muto, Memi; Sakai, Mizuki; Kondo, Hirofumi; Kobayashi, Shintaro; Kariwa, Hiroaki; Yoshii, Kentaro

2017-09-12

Neurological diseases caused by encephalitic flaviviruses are severe and associated with high levels of mortality. However, little is known about the detailed mechanisms of viral replication and pathogenicity in the brain. Previously, we reported that the genomic RNA of tick-borne encephalitis virus (TBEV), a member of the genus Flavivirus , is transported and replicated in the dendrites of neurons. In the present study, we analyzed the transport mechanism of the viral genome to dendrites. We identified specific sequences of the 5' untranslated region of TBEV genomic RNA that act as a cis -acting element for RNA transport. Mutated TBEV with impaired RNA transport in dendrites caused a reduction in neurological symptoms in infected mice. We show that neuronal granules, which regulate the transport and local translation of dendritic mRNAs, are involved in TBEV genomic RNA transport. TBEV genomic RNA bound an RNA-binding protein of neuronal granules and disturbed the transport of dendritic mRNAs. These results demonstrated a neuropathogenic virus hijacking the neuronal granule system for the transport of viral genomic RNA in dendrites, resulting in severe neurological disease.

Resource Conservation and Recovery Act (RCRA) and Federal Facilities

EPA Pesticide Factsheets

Federal facilities have responsibilities with hazardous waste under RCRA, including the generation, transportation, treatment, storage, and disposal under the Resource Conservation and Recovery Act (RCRA). .

Payload transportation system study

NASA Technical Reports Server (NTRS)

1976-01-01

A standard size set of shuttle payload transportation equipment was defined that will substantially reduce the cost of payload transportation and accommodate a wide range of payloads with minimum impact on payload design. The system was designed to accommodate payload shipments between the level 4 payload integration sites and the launch site during the calendar years 1979-1982. In addition to defining transportation multi-use mission support equipment (T-MMSE) the mode of travel, prime movers, and ancillary equipment required in the transportation process were also considered. Consistent with the STS goals of low cost and the use of standardized interfaces, the transportation system was designed to commercial grade standards and uses the payload flight mounting interfaces for transportation. The technical, cost, and programmatic data required to permit selection of a baseline system of MMSE for intersite movement of shuttle payloads were developed.

NMR studies of cation transport across membranes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shochet, N.R.

1985-01-01

/sup 23/Na NMR Studies of cation transport across membranes were conducted both on model and biological membranes. Two ionophores, the carrier monensin and the channel-former gramicidin, were chosen to induce cation transport in large unilamellar phosphatidylcholine vesicles. The distinction between the NMR signals arising from the two sides of the membrane was achieved by the addition of an anionic paramagnetic shift reagent to the outer solution. The kinetics of the cation transport across the membrane was observed simultaneously monitoring the changes in the /sup 23/Na NMR signals of both compartments. Two mathematical models were developed for the estimation of themore » transport parameters of the monensin- and gramicidin-induced cation transport. The models were able to fit the experimental data very well. A new method for the estimation of the volume trapped inside the vesicles was developed. The method uses the relative areas of the intra- and extravesicular NMR signals arising from a suspension of vesicles bathed in the same medium they contain, as a measure for the relative volumes of these compartments. Sodium transport across biological membranes was studied by /sup 23/ NMR, using suspensions of cultured nerve cells. The sodium influx through voltage-gated channels was studied using the channel modifier batrachotoxin in combination with scorpion toxin.« less

Detonation wave propagation and interaction with transportation infrastructure

DOT National Transportation Integrated Search

2008-01-01

The recent establishment of the National University Transportation Center at MST under the "Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users," expands the research and education activities to include alternative tr...

77 FR 2345 - Advisory Council on Transportation Statistics; Request for Nominations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-17

... Transportation Statistics Advisory Council on Transportation Statistics; Request for Nominations AGENCY: Research and Innovative Technology Administration (RITA), Bureau of Transportation Statistics (BTS), DOT. ACTION: Request for Nominations to the Advisory Council on Transportation Statistics (ACTS). SUMMARY: The...

Global energy transports and the influence of clouds on transport requirements - A satellite analysis

NASA Technical Reports Server (NTRS)

Sohn, Byung-Ju; Smith, Eric A.

1992-01-01

This report investigates the impact of differential net radiative heating on 2D energy transports within the atmosphere ocean system and the role of clouds on this process. The 2D mean energy transports, in answer to zonal and meridional gradients in the net radiation field, show an east-west coupled dipole structure in which the Pacific acts as the major energy source and North Africa as the major energy sink. It is demonstrated that the dipole is embedded in the secondary energy transports arising mainly from the differential heating between land and oceans in the tropics in which the tropical east-west (zonal) transports are up to 30 percent of the tropical north-south (meridional) transports.

7 CFR 17.8 - Ocean transportation.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 1 2012-01-01 2012-01-01 false Ocean transportation. 17.8 Section 17.8 Agriculture... THE AGRICULTURAL TRADE DEVELOPMENT AND ASSISTANCE ACT OF 1954, AS AMENDED § 17.8 Ocean transportation. (a) General. (1) This section applies to the financing of ocean freight or ocean freight differential...

7 CFR 17.8 - Ocean transportation.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 1 2014-01-01 2014-01-01 false Ocean transportation. 17.8 Section 17.8 Agriculture... THE AGRICULTURAL TRADE DEVELOPMENT AND ASSISTANCE ACT OF 1954, AS AMENDED § 17.8 Ocean transportation. (a) General. (1) This section applies to the financing of ocean freight or ocean freight differential...

7 CFR 17.8 - Ocean transportation.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 1 2013-01-01 2013-01-01 false Ocean transportation. 17.8 Section 17.8 Agriculture... THE AGRICULTURAL TRADE DEVELOPMENT AND ASSISTANCE ACT OF 1954, AS AMENDED § 17.8 Ocean transportation. (a) General. (1) This section applies to the financing of ocean freight or ocean freight differential...

7 CFR 17.8 - Ocean transportation.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 1 2011-01-01 2011-01-01 false Ocean transportation. 17.8 Section 17.8 Agriculture... THE AGRICULTURAL TRADE DEVELOPMENT AND ASSISTANCE ACT OF 1954, AS AMENDED § 17.8 Ocean transportation. (a) General. (1) This section applies to the financing of ocean freight or ocean freight differential...

Alternative Transportation Study : Monomoy National Wildlife Refuge.

DOT National Transportation Integrated Search

2010-05-31

This report provides an overview of the historic and current visitation, infrastructure, and transportation conditions related to Monomoy National Wildlife Refuge and the surrounding areas in Chatham, MA. The study defines transportation-related goal...

75 FR 18254 - Advisory Council on Transportation Statistics; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-09

... DEPARTMENT OF TRANSPORTATION Bureau of Transportation Statistics Advisory Council on Transportation Statistics; Notice of Meeting AGENCY: Research and Innovative Technology Administration, U.S... the Advisory Council on Transportation Statistics (ACTS). This 90 minute Web conference will be held...

3 CFR - The Energy Independence and Security Act of 2007

Code of Federal Regulations, 2010 CFR

2010-01-01

... 3 The President 1 2010-01-01 2010-01-01 false The Energy Independence and Security Act of 2007 Presidential Documents Other Presidential Documents Memorandum of January 26, 2009 The Energy Independence and Security Act of 2007 Memorandum for the Secretary of Transportation [and] the Administrator of the National Highway Traffic Safety...

Nebraska Department of Transportation - Clean Water Act Public Notice

EPA Pesticide Factsheets

The EPA is providing notice of a proposed Administrative Penalty Assessment against the Nebraska Department of Transportation, a state agency located at 1500 Highway 2, Lincoln, NE 68509, for alleged violations of its municipal separate stormwater sewer sy

Studies on the biosynthesis and intracellular transport of gangliosides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farrer, R.G.

1987-01-01

Ganglioside biosynthesis and transport to myelin was studied in brainstem of 17-21 day old rats. Brainstem slices were incubated for up to 2 hours with (/sup 3/H)glucosamine, and gangliosides were isolated by column chromatography and HPTLC. Results from these experiments showed that: (a) ganglioside synthesis was decreased in the slices compared to in vivo, and this decrease was greater in the more complex gangliosides than in the simpler ones; (b) label incorporation into gangliosides GM3 and GM2 increased in a linear fashion, whereas the rate of incorporation continuously increased over the 2 hour period for the more complex gangliosides; (c)more » label incorporated into gangliosides, which showed almost no effect of chase after 30 minutes; (d) monensin at 0.1 uM inhibited the synthesis of all gangliosides except GM3, GM2 and GD3. Compartmentation of ganglioside biosynthesis was examined by analyzing the subcellular location of two ganglioside synthesizing enzymes, lactosylceramide sialosyltransferase (LCST) and GDlb sialosyltransferase (GDlbST), acting early and late in the ganglioside pathway, respectively.« less

Iowa Department of Transportation. - Clean Water Act Public Notice

EPA Pesticide Factsheets

The EPA is providing notice of a proposed Administrative Penalty Assessment against Iowa Department of Transportation, a state agency with its primary office located at 800 Lincoln Way, Ames, IA 50010, for alleged violations at two roadway construction pro

77 FR 60170 - Americans With Disabilities Act: Proposed Circular Chapter, Vehicle Acquisition

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-02

... With Disabilities Act: Proposed Circular Chapter, Vehicle Acquisition AGENCY: Federal Transit...) Americans with Disabilities Act (ADA) regulations. This proposed chapter on vehicle acquisition is the first... requirements transportation providers must follow to ensure their services, vehicles, and facilities are...

Commercial Orbital Transportation Services (COTS) Demonstrations

NASA Technical Reports Server (NTRS)

Lindenmoyer, Allan

2006-01-01

U.S. space policy directs pursuit of commercial opportunities for providing transportation and other services low Earth orbit and beyond. COTS Project established to implement policy. COTS strategy: Phase 1) Assist industry with system development/demonstrations (COTS Demos); Phase 2) Procure commercial services for ISS logistics support. COTS Demonstrations competition completed in 10 months. Two industry partners selected for funded Space Act Agreements: 1) SpaceX & Rocketplane-Kistler; and 2) Unfunded Space Act Agreements in work with other competitors. COTS budget of $500 M thru 2010, with pay for performance milestone approach. Cargo flight demonstrations planned for 2008 and 2009: Crew flight demonstration options for 2011-2012. Commercial cargo transportation services potentially available as early as 2009-2010. Successful COTS partners may open new space markets and provide reliable, cost effective cargo and crew transportation services, a new era for commercial space.

36 CFR Appendix C to Part 1191 - Architectural Barriers Act: Scoping

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Architectural Barriers Act: Scoping C Appendix C to Part 1191 Parks, Forests, and Public Property ARCHITECTURAL AND TRANSPORTATION... FACILITIES; ARCHITECTURAL BARRIERS ACT (ABA) ACCESSIBILITY GUIDELINES Pt. 1191, App. C Appendix C to Part...

36 CFR Appendix C to Part 1191 - Architectural Barriers Act: Scoping

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Architectural Barriers Act: Scoping C Appendix C to Part 1191 Parks, Forests, and Public Property ARCHITECTURAL AND TRANSPORTATION... FACILITIES; ARCHITECTURAL BARRIERS ACT (ABA) ACCESSIBILITY GUIDELINES Pt. 1191, App. C Appendix C to Part...

36 CFR Appendix C to Part 1191 - Architectural Barriers Act: Scoping

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Architectural Barriers Act: Scoping C Appendix C to Part 1191 Parks, Forests, and Public Property ARCHITECTURAL AND TRANSPORTATION... FACILITIES; ARCHITECTURAL BARRIERS ACT (ABA) ACCESSIBILITY GUIDELINES Pt. 1191, App. C Appendix C to Part...

MacMillan Pier Transportation Center Feasibility Study.

DOT National Transportation Integrated Search

2006-06-01

The MacMillan Pier Transportation Center Feasibility Study examines two potential sites (landside and waterside) for a transportation center that provides a range of tourist and traveler information. It would serve as a gateway for Provincetown and t...

Cabrillo College Transportation Study.

ERIC Educational Resources Information Center

Willett, Terrence

This report provides results of the survey and other sources of information which have been used to develop a transportation management plan at Cabrillo College (California). In 2000, Cabrillo College organized a Transportation Management Committee to review the existing transportation situation and develop and implement a plan with the goal of…

Assateague Island National Seashore alternative transportation systems planning study and business plan for alternative transportation

DOT National Transportation Integrated Search

2012-08-31

The purpose of this study was to (1) study the potential expansion of existing alternative transportation systems (bicycle facilities) and development of new alternative transportation systems in and around the Maryland District of Assateague Island ...

75 FR 54543 - Americans With Disabilities Act (ADA) Accessibility Guidelines for Transportation Vehicles

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-08

... ARCHITECTURAL AND TRANSPORTATION BARRIERS COMPLIANCE BOARD 36 CFR Part 1192 [Docket No. ATBCB 2010... Vehicles AGENCY: Architectural and Transportation Barriers Compliance Board. ACTION: Notice of public hearings. SUMMARY: The Architectural and Transportation Barriers Compliance Board (Access Board) will hold...

Transportation statistics beyond ISTEA : critical gaps and strategic responses

DOT National Transportation Integrated Search

1998-01-01

The effectiveness and efficiency of transportation relies heavily on sound information. In response to the growing information gap, the Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA) resurrected several key data-collection programs,...

Transportation and the environment : a research agenda for Oregon.

DOT National Transportation Integrated Search

2006-08-01

The Safe, Accountable, Flexible, Efficient, Transportation Equity Act: A Legacy for Users (SAFETEA-LU) has established two new research programs the Surface Transportation Environment Planning (STEP) Cooperative Research Program and the Future St...

Spin transport studies in encapsulated CVD graphene

NASA Astrophysics Data System (ADS)

Avsar, Ahmet; You Tan, Jun; Ho, Yuda; Koon, Gavin; Oezyilmaz, Barbaros

2013-03-01

Spin transport studies in exfoliated graphene on SiO2/Si substrates have shown spin relaxation times that are orders of magnitude shorter than the theoretical predictions. Similar to the charge transport case, the underlying substrate is expected to be the limiting factor. The recent work Zomer, P. J. et al. shows that spin transport over lengths up to 20um is possible in high mobility exfoliated graphene devices on boron nitride (BN) substrates. Here we discuss our initial attempts to repeat such spin transport experiments with CVD graphene on BN substrates. The effect of encapsulation of such devices with an extra BN layer will be also discussed.

High-speed civil transport study. Summary

NASA Technical Reports Server (NTRS)

1989-01-01

A system of study of the potential for a high speed commercial transport aircraft addressed technology, economic, and environmental constraints. Market projections indicated a need for fleets of transport with supersonic or greater cruise speeds by the years 2000 to 2005. The associated design requirements called for a vehicle to carry 250 to 300 passengers over a range of 5000 to 6000 nautical miles. The study was initially unconstrained in terms of vehicle characteristics, such as cruise speed, propulsion systems, fuels, or structural materials. Analyses led to a focus on the most promising vehicle concepts. These were concepts that used a kerosene type fuel and cruised at Mach numbers between 2.0 to 3.2. Further systems study identified the impact of environmental constraints (for community noise, sonic boom, and engine emissions) on economic attractiveness and technological needs. Results showed that current technology cannot produce a viable high speed civil transport. Significant advances are needed to take off gross weight and allow for both economic attractiveness and environment acceptability. Specific technological requirements were identified to meet these needs.

Dynamic transport study of the plasmas with transport improvement in LHD and JT-60U

NASA Astrophysics Data System (ADS)

Ida, K.; Sakamoto, Y.; Inagaki, S.; Takenaga, H.; Isayama, A.; Matsunaga, G.; Sakamoto, R.; Tanaka, K.; Ide, S.; Fujita, T.; Funaba, H.; Kubo, S.; Yoshinuma, M.; Shimozuma, T.; Takeiri, Y.; Ikeda, K.; Michael, C.; Tokuzawa, T.; LHD experimental Group; JT-60 Team

2009-01-01

Transport analysis during the transient phase of heating (a dynamic transport study) applied to the plasma with internal transport barriers (ITBs) in the Large Helical Device (LHD) heliotron and the JT-60U tokamak is described. In the dynamic transport study the time of transition from the L-mode plasma to the ITB plasma is clearly determined by the onset of flattening of the temperature profile in the core region and a spontaneous phase transition from a zero curvature ITB (hyperbolic tangent shaped ITB) or a positive curvature ITB (concaved shaped ITB) to a negative curvature ITB (convex shaped ITB) and its back-transition are observed. The flattening of the core region of the ITB transition and the back-transition between a zero curvature ITB and a convex ITB suggest the strong interaction of turbulent transport in space.

29 CFR 1202.12 - National Air Transport Adjustment Board.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 4 2011-07-01 2011-07-01 false National Air Transport Adjustment Board. 1202.12 Section... § 1202.12 National Air Transport Adjustment Board. Under section 205, title II, of the Railway Labor Act... four representatives to constitute a Board known as the National Air Transport Adjustment Board. Two...

29 CFR 1202.12 - National Air Transport Adjustment Board.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false National Air Transport Adjustment Board. 1202.12 Section... § 1202.12 National Air Transport Adjustment Board. Under section 205, title II, of the Railway Labor Act... four representatives to constitute a Board known as the National Air Transport Adjustment Board. Two...

Year 2015 transportation plan : Huntsville Area Transportation Study

DOT National Transportation Integrated Search

1995-04-01

The Year 2015 Transportation Plan is an intermodal plan that considers all modes of the existing transportation system, identifies needs, provides policy direction and defines the goals for planning and : project development in the Huntsville urban a...

Transportation planning effectiveness: twenty case studies

DOT National Transportation Integrated Search

1977-12-31

This document consists of 20 site-specific case studies of urban area experience with the Technical Study Grant Program of the Urban Mass Transportation Administration (UMTA). The objective of the case studies is to determine how the Technical Study ...

Development of performance measurement for freight transportation : [tech summary].

DOT National Transportation Integrated Search

2014-09-01

With increased emphasis on intermodal transportation development, the issue of how to evaluate an intermodal system has : been receiving intensive attention since the enactments of the Intermodal Surface Transportation E ciency Act (ISTEA) and the...

Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Wing planform study and final configuration selection

NASA Technical Reports Server (NTRS)

1981-01-01

This report summarizes the Wing Planform Study Task and Final Configuration Selection of the Integrated Application of Active Controls (IAAC) Technology Project within the Energy Efficient Transport Program. Application of Active Controls Technology (ACT) in combination with increased wing span resulted in significant improvements over the Conventional Baseline Configuration (Baseline) and the Initial ACT Configuration previously established. The configurations use the same levels of technology (except for ACT), takeoff gross weight, and payload as the Baseline. The Final ACT Configuration (Model 768-107) incorporates pitch-augmented stability (which enabled an approximately 10% aft shift in cruise center of gravity and a 45% reduction in horizontal tail sizes), lateral/directional-augmented stability, an angle-of-attack limiter, and wing-load alleviation. Flutter-mode control was not beneficial for this configuration. This resulted in an 890 kg (1960 lb) reduction in airplane takeoff gross weight and a 9.8% improvement in cruise lift/drag. At the Baseline mission range (3590 km) (1938 nmi), this amounts to 10% block fuel reduction. Good takeoff performance at high-altitude airports on a hot day was also achieved. Results of this task strongly indicate that the IAAC Project should proceed with the Final ACT evaluation and begin the required control system development and testing.

Agricultural Industries Transportation Services (AITS) statewide needs assessment study.

DOT National Transportation Integrated Search

2003-05-01

The California Department of Transportation (Caltrans) funded the Agricultural Industries Transportation Services Statewide Needs Assessment Study to determine the existence and extent of the unmet transportation needs among the states agricultura...

75 FR 26183 - Procedures for Transportation Workplace Drug and Alcohol Testing Programs

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-11

... Omnibus Transportation Employee Testing Act of 1991 (49 U.S.C. 102, 301, 322, 5331, 20140, 31306, and 45101 et seq.) and the Department of Transportation Act (49 U.S.C. 322). This proposed rule is a non... follows: Authority: 49 U.S.C. 102, 301, 322, 5331, 20140, 31306, and 45101 et seq. 2. In Appendix G to...

Report to Congress : Surface Transportation Research and Development Plan : Fourth Edition

DOT National Transportation Integrated Search

1997-01-01

Section 6009(b) of the Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA) requires that the U.S. Department of Transportation (DOT) develop an integrated National Surface Transportation Research and Development (R&D) Plan that focuses o...

77 FR 13606 - Ocean Transportation Intermediary License Revocation

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-07

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary license has been revoked pursuant to section 19 of the Shipping Act of 1984 (46 U.S.C. Chapter 409) and the...

77 FR 50689 - Ocean Transportation Intermediary License Reissuances

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-22

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Reissuances The Commission gives notice that the following Ocean Transportation Intermediary licenses have been reissued pursuant to section 40901 of the Shipping Act of 1984 (46 U.S.C. 40101). License No.: 015255N. Name: Triways...

Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Current and advanced act control system definition study, volume 1

NASA Technical Reports Server (NTRS)

Hanks, G. W.; Shomber, H. A.; Dethman, H. A.; Gratzer, L. B.; Maeshiro, A.; Gangsaas, D.; Blight, J. D.; Buchan, S. M.; Crumb, C. B.; Dorwart, R. J.

1981-01-01

An active controls technology (ACT) system architecture was selected based on current technology system elements and optimal control theory was evaluated for use in analyzing and synthesizing ACT multiple control laws. The system selected employs three redundant computers to implement all of the ACT functions, four redundant smaller computers to implement the crucial pitch-augmented stability function, and a separate maintenance and display computer. The reliability objective of probability of crucial function failure of less than 1 x 10 to the -9th power per flight of 1 hr can be met with current technology system components, if the software is assumed fault free and coverage approaching 1.0 can be provided. The optimal control theory approach to ACT control law synthesis yielded comparable control law performance much more systematically and directly than the classical s-domain approach. The ACT control law performance, although somewhat degraded by the inclusion of representative nonlinearities, remained quite effective. Certain high-frequency gust-load alleviation functions may require increased surface rate capability.

50 CFR 17.4 - Pre-Act wildlife.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 50 Wildlife and Fisheries 2 2010-10-01 2010-10-01 false Pre-Act wildlife. 17.4 Section 17.4 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND...

50 CFR 17.4 - Pre-Act wildlife.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 2 2011-10-01 2011-10-01 false Pre-Act wildlife. 17.4 Section 17.4 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND...

50 CFR 17.4 - Pre-Act wildlife.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 2 2013-10-01 2013-10-01 false Pre-Act wildlife. 17.4 Section 17.4 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND...

50 CFR 17.4 - Pre-Act wildlife.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 50 Wildlife and Fisheries 2 2012-10-01 2012-10-01 false Pre-Act wildlife. 17.4 Section 17.4 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND...

50 CFR 17.4 - Pre-Act wildlife.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 50 Wildlife and Fisheries 2 2014-10-01 2014-10-01 false Pre-Act wildlife. 17.4 Section 17.4 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED) TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND...

High-speed civil transport study: Special factors

NASA Technical Reports Server (NTRS)

1990-01-01

Studies relating to environmental factors associated with high speed civil transports were conducted. Projected total engine emissions for year 2015 fleets of several subsonic/supersonic transport fleet scenarios, discussion of sonic boom reduction methods, discussion of community noise level requirements, fuels considerations, and air traffic control impact are presented.

48 CFR 47.403 - Guidelines for implementation of the Fly America Act.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Guidelines for implementation of the Fly America Act. 47.403 Section 47.403 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TRANSPORTATION Air Transportation by U.S.-Flag Carriers 47.403...

Experimental Study of Lunar Dust Transportation due to Electrostatic Forces and Micro-meteorite Impacts

NASA Astrophysics Data System (ADS)

Orger, N. C.; Toyoda, K.; Cho, M.

2017-12-01

Lunar dust particles can be transported via several physical mechanisms above the surface, and the electrostatic dust lofting was suspected to be the responsible mechanism for the high-altitude lunar horizon glow above the terminator region. Most of the recent studies have shown that contact forces acting on the dust grains of sub-micrometer and micrometer sizes are much larger than the electrostatic forces resulting from the ambient plasma conditions; however, the electrostatic forces are strong enough to accelerate the lunar dust grains to high altitudes once the dust particles are separated from the surface by an initial mechanism. In this study our purpose is to investigate if the dust particles can be transported under the electrostatic forces after they are released from the surface by the micrometeorite impacts. It is expected to be the most of the dust grains will be launched from the elastic deformation regions, and the contact forces will be canceled after they are moved tens of nanometers. For the experiments, silica particles are used in a cavity with 2 cm diameter and 5 mm depth on the graphite plates. First, the dust particles are baked under an infrared lamp to release the absorbed atmospheric particles in the vacuum chamber. Second, the electron beam source emits electrons with 100 - 200 eV energies, and a Faraday cup measures the electron current in the vacuum chamber. Third, a laser beam is used to simulate micro-meteorite impacts, and the results are monitored with a high speed camera mostly focusing on the elastic deformation region. Therefore, this study investigates how the impacts modify the dust transportation as an initial mechanism for electrostatic dust lofting to high altitudes.

National Urban Mass Transportation Statistics (1982 - Section 15 Report)

DOT National Transportation Integrated Search

1983-11-01

This report summarizes the financial and operating data submitted annually to the Urban Mass Transportation Administration (UMTA) by the nation's public transit operators, pursuant to Section 15 of the Urban Mass Transportation (UMT) Act of 1964, as ...

A study of characteristics of intercity transportation systems. Phase 1: Definition of transportation comparison methodology

NASA Technical Reports Server (NTRS)

English, J. M.; Smith, J. L.; Lifson, M. W.

1978-01-01

The objectives of this study are: (1) to determine a unified methodological framework for the comparison of intercity passenger and freight transportation systems; (2) to review the attributes of existing and future transportation systems for the purpose of establishing measures of comparison. These objectives were made more specific to include: (1) development of a methodology for comparing long term transportation trends arising from implementation of various R&D programs; (2) definition of value functions and attribute weightings needed for further transportation goals.

Overview of the ACT program

NASA Technical Reports Server (NTRS)

Davis, John G., Jr.

1992-01-01

NASA's Advanced Composites Program (ACT) was initiated in 1988. A National Research Announcement was issued to solicit innovative ideas that could significantly contribute to development and demonstration of an integrated technology data base and confidence level that permits cost-effective use of composite primary structures in transport aircraft. Fifteen contracts were awarded by the Spring of 1989 and the participants include commercial and military airframe manufacturers, materials developers and suppliers, universities, and government laboratories. The program approach is to develop materials, structural mechanics methodology, design concepts, and fabrication procedures that offer the potential to make composite structures cost-effective compared to aluminum structure. Goals for the ACT program included 30-50 percent weight reduction, 20-25 percent acquisition cost reduction, and provided the scientific basis for predicting materials and structures performance. This paper provides an overview of the ACT program status, plans, and selected technical accomplishments. Sixteen additional papers, which provide more detailed information on the research and development accomplishments, are contained in this publication.

Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Wing planform study and final configuration selection

NASA Technical Reports Server (NTRS)

1981-01-01

The Wing Planform Study and Final Configuration Selection Task of the Integrated Application of Active Controls (IAAC) Technology Project within the Energy Efficient Transport Program is documented. Application of Active Controls Technology (ACT) in combination with increased wing span resulted in significant improvements over the Conventional Baseline Configuration (Baseline) and the Initial ACT Configuration previously established. The configurations use the same levels of technology, takeoff gross weight, and payload as the Baseline. The Final ACT Configuration (Model 768-107) incorporates pitch-augmented stability (which enabled an approximately 10% aft shift in cruise center of gravity and a 44% reduction in horizontal tail size), lateral/directional-augmented stability, an angle-of-attack limiter, and wing-load alleviation. Flutter-mode control was not beneficial for this configuration. This resulted in an 890 kg (1960 lb) reduction in airplane takeoff gross weight and a 9.8% improvement in cruise lift/drag. At the Baseline mission range (3589 km 1938 nmi), this amounts to 10% block-fuel reduction. Results of this task strongly indicate that the IAAC Project should proceed with the Final ACT evaluation, and begin the required control system development and test.

76 FR 72408 - Ocean Transportation Intermediary License Reissuance

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-23

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Reissuance Notice is hereby given that the following Ocean Transportation Intermediary license has been reissued by the Federal Maritime Commission pursuant to section 19 of the Shipping Act of 1984 (46 U.S.C. chapter 409) and the...

76 FR 76411 - Ocean Transportation Intermediary License; Reissuance

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-07

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Reissuance Notice is hereby given that the following Ocean Transportation Intermediary licenses have been reissued by the Federal Maritime Commission pursuant to section 19 of the Shipping Act of 1984 (46 U.S.C. chapter 409) and the...

77 FR 13605 - Ocean Transportation Intermediary License; Reissuance

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-07

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License; Reissuance Notice is hereby given that the following Ocean Transportation Intermediary licenses have been reissued by the Federal Maritime Commission pursuant to section 19 of the Shipping Act of 1984 (46 U.S.C. chapter 409) and the...

75 FR 31438 - Ocean Transportation Intermediary License Applicants

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-03

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Applicants Notice is hereby... application for a license as a Non- Vessel-Operating Common Carrier (NVO) and/or Ocean Freight Forwarder (OFF)--Ocean Transportation Intermediary (OTI) pursuant to section 19 of the Shipping Act of 1984 as amended...

78 FR 64941 - Ocean Transportation Intermediary License Reissuances

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-30

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Reissuances The Commission gives notice that the following Ocean Transportation Intermediary license has been reissued pursuant to section 19 of the Shipping Act of 1984 (46 U.S.C. 40101). License No.: 024003N. Name: Concord Atlantic Inc...

77 FR 58379 - Ocean Transportation Intermediary License Reissuances

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-20

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Reissuances The Commission gives notice that the following Ocean Transportation Intermediary licenses have been reissued pursuant to section 40901 of the Shipping Act of 1984 (46 U.S.C. 40101). License No.: 022710F. Name: Route 809...

78 FR 24200 - Ocean Transportation Intermediary License Reissuances

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-24

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Reissuances The Commission gives notice that the following Ocean Transportation Intermediary licenses have been reissued pursuant to section 19 of the Shipping Act of 1984 (46 U.S.C. 40101). License No.: 018413F. Name: Chicago Int...

78 FR 25741 - Ocean Transportation Intermediary License Reissuances

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-02

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Reissuances The Commission gives notice that the following Ocean Transportation Intermediary license has been reissued pursuant to section 19 of the Shipping Act of 1984 (46 U.S.C. 40101). License No.: 018839NF. Name: Aliana Express, Inc...

77 FR 72863 - Ocean Transportation Intermediary License Reissuances

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-06

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Reissuances The Commission gives notice that the following Ocean Transportation Intermediary licenses have been reissued pursuant to section 19 of the Shipping Act of 1984 (46 U.S.C. 40101) effective on the date shown. License No...

Transportation and Children Who Have Disabilities. Alliance Action Information Sheets

ERIC Educational Resources Information Center

Technical Assistance ALLIANCE for Parent Centers, 2007

2007-01-01

The Individuals with Disabilities Education Act (IDEA) includes transportation within its definition of "related services." This means that students with Individualized Education Programs (IEPs) have the right to receive special transportation services if it is needed. Transportation and assistance may be provided to a child whose…

Safety Study of Double-Decker Motorcoaches with Rear Luggage Compartment

DOT National Transportation Integrated Search

2017-06-06

Section 5510 of Fixing Americas Surface Transportation Act, 2015 (FAST Act) required the Secretary of Transportation to conduct a study on the effects of attaching a luggage compartment to the rear of a double-decker motorcoach, with respect to sa...

Human Transportation System (HTS) study: Executive summary

NASA Technical Reports Server (NTRS)

Lance, N.; Geyer, M. S.; Gaunce, M. T.

1993-01-01

Work completed under the Human Transportation System Study is summarized. This study was conducted by the New Initiatives Office at JSC with the technical support of Boeing, General Dynamics, Lockheed, McDonnell-Douglas, Martin Marietta, and Rockwell. The study was designed to generate information on determining the appropriate path to follow for new system development to meet the Nation's space transportation needs. The study evaluates 18 transportation architecture options using a parametric set of mission requirements. These options include use of current systems as well as proposed systems to assess the impact of various considerations, such as the cost of alternate access, or the benefit of separating people and cargo. The architecture options are compared to each other with six measurable evaluation criteria or attributes. They are the following: funding profile, human safety, probability of mission success, architecture cost risk, launch schedule confidence, and environmental impact. Values for these attributes are presented for the architecture options, with pertinent conclusions and recommendations.

Human Transportation System (HTS) study, volume 1

NASA Technical Reports Server (NTRS)

Lance, N.; Geyer, M. S.; Gaunce, M. T.

1993-01-01

Work completed under the Human Transportation System Study is summarized. This study was conducted by the New Initiatives Office at JSC with the technical support of Boeing, General Dynamics, Lockheed, McDonnell-Douglas, Martin Marietta, and Rockwell. The study was designed to generate information on determining the appropriate path to follow for new system development to meet the Nation's space transportation needs. The study evaluates 18 transportation architecture options using a parametric set of mission requirements. These options include use of current systems as well as proposed systems to assess the impact of various considerations, such as the cost of alternate access, or the benefit of separating people and cargo. The architecture options are compared to each other with six measurable evaluation criteria or attributes. They are the following: funding profile, human safety, probability of mission success, architecture cost risk, launch schedule confidence, and environmental impact. Values for these attributes are presented for the architecture options, with pertinent conclusions and recommendations.

23 CFR 450.318 - Transportation planning studies and project development.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Transportation planning studies and project development... § 450.318 Transportation planning studies and project development. (a) Pursuant to section 1308 of the... transportation operator(s) may undertake a multimodal, systems-level corridor or subarea planning study as part...

77 FR 70163 - Ocean Transportation Intermediary License Revocations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-23

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocations The Commission gives notice that the following Ocean Transportation Intermediary license has been revoked pursuant to section 19 of the Shipping Act of 1984 (46 U.S.C. 40101) effective on the date shown. License No.: 022069N...

77 FR 68779 - Ocean Transportation Intermediary License Revocations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-16

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocations The Commission gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to section 19 of the Shipping Act of 1984 (46 U.S.C. 40101) effective on the date shown. License No.: 3667NF...

75 FR 19624 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-15

... Transportation and Related Agencies Appropriations Act 2001; 5 U.S.C. 6120, Telecommuting in Executive Agencies... by telephone control offices to validate and reimburse participants for costs associated with...

Paracellular transport as a strategy for energy conservation by multicellular organisms?

PubMed

Yu, Alan S L

2017-04-03

Paracellular transport of solutes and water accompanies transcellular transport across epithelial barriers and together they serve to maintain internal body composition. However, whether paracellular transport is necessary and why it evolved is unknown. In this commentary I discuss our recent studies to address this question in the proximal tubule of the kidney. Paracellular reabsorption of sodium occurs in the proximal tubule and is mediated by claudin-2. However, deletion of claudin-2 in mice does not affect whole kidney sodium excretion because it can be completely compensated by downtream transcellular transport mechanisms. This occurs at the expense of increased oxygen consumption, tissue hypoxia and increased susceptibility to ischemic injury. It is concluded that paracellular transport acts as an energy saving mechanism to increase transport without consuming additional oxygen. It is speculated that this might be why paracellular transport evolved in leaky epithelia with high transport needs.

Paracellular transport as a strategy for energy conservation by multicellular organisms?

PubMed Central

Yu, Alan S. L.

2017-01-01

ABSTRACT Paracellular transport of solutes and water accompanies transcellular transport across epithelial barriers and together they serve to maintain internal body composition. However, whether paracellular transport is necessary and why it evolved is unknown. In this commentary I discuss our recent studies to address this question in the proximal tubule of the kidney. Paracellular reabsorption of sodium occurs in the proximal tubule and is mediated by claudin-2. However, deletion of claudin-2 in mice does not affect whole kidney sodium excretion because it can be completely compensated by downtream transcellular transport mechanisms. This occurs at the expense of increased oxygen consumption, tissue hypoxia and increased susceptibility to ischemic injury. It is concluded that paracellular transport acts as an energy saving mechanism to increase transport without consuming additional oxygen. It is speculated that this might be why paracellular transport evolved in leaky epithelia with high transport needs. PMID:28452575

Influence of coal slurry particle composition on pipeline hydraulic transportation behavior

NASA Astrophysics Data System (ADS)

Li-an, Zhao; Ronghuan, Cai; Tieli, Wang

2018-02-01

Acting as a new type of energy transportation mode, the coal pipeline hydraulic transmission can reduce the energy transportation cost and the fly ash pollution of the conventional coal transportation. In this study, the effect of average velocity, particle size and pumping time on particle composition of coal particles during hydraulic conveying was investigated by ring tube test. Meanwhile, the effects of particle composition change on slurry viscosity, transmission resistance and critical sedimentation velocity were studied based on the experimental data. The experimental and theoretical analysis indicate that the alter of slurry particle composition can lead to the change of viscosity, resistance and critical velocity of slurry. Moreover, based on the previous studies, the critical velocity calculation model of coal slurry is proposed.

A transportation corridor analysis toolkit.

DOT National Transportation Integrated Search

2013-10-01

The Moving Ahead for Progress in the 21st Century Act includes a number of provisions advocating : improving the condition and performance of the national freight network through targeted investments and : policies by the Department of Transportation...

Transportation fuel research and development : statistically validated codes and standards

DOT National Transportation Integrated Search

2007-08-28

The recent establishment of the National University Transportation Center at MST under the "Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users," expands the research and education activities to include alternative tr...

75 FR 24773 - Research and Innovative Technology Administration Advisory Council on Transportation Statistics...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-05

... DEPARTMENT OF TRANSPORTATION Bureau of Transportation Statistics Research and Innovative Technology Administration Advisory Council on Transportation Statistics; Notice of Meeting AGENCY: Research...-363; 5 U.S.C. app. 2), a meeting of the Advisory Council on Transportation Statistics (ACTS). The...

Multimodal transportation planning in Virginia : past practices and new opportunities.

DOT National Transportation Integrated Search

1994-09-01

The Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA) provided the : nation with a means of maintaining its existing infrastructure while laying the foundation for a : national intermodal transportation system. ISTEA was passed to ensu...

Carbon Nanotubes Act as Contaminant Carriers and Translocate within Plants

NASA Astrophysics Data System (ADS)

Chen, Guosheng; Qiu, Junlang; Liu, Yan; Jiang, Ruifen; Cai, Siying; Liu, Yuan; Zhu, Fang; Zeng, Feng; Luan, Tiangang; Ouyang, Gangfeng

2015-10-01

Nanotechnology permits broad advances in agriculture. However, as it is still at a relatively early stage of development, the potential risks remain unclear. Herein, for the first time, we reveal the following: 1) the impact of multi-walled carbon nanotubes (MWCNTs) on the accumulation/depuration behaviors of contaminants in crop, mustard (Brassica juncea), and 2) the permeability and transportability of MWCNTs in intact mature mustard plants. Using an in vivo sampling technique, the kinetic accumulation/depuration processes of several contaminants in mustard plans exposed to MWCNTs were traced, and an enhancement of contaminant accumulation in living plants was observed. Meanwhile, we observed that the MWCNTs permeated into the roots of intact living plants (three months old) and were then transported to the upper organs under the force of transpiration steam. This study demonstrated that MWCNTs can act as contaminant carriers and be transported to the edible parts of crops.

Carbon Nanotubes Act as Contaminant Carriers and Translocate within Plants

PubMed Central

Chen, Guosheng; Qiu, Junlang; Liu, Yan; Jiang, Ruifen; Cai, Siying; Liu, Yuan; Zhu, Fang; Zeng, Feng; Luan, Tiangang; Ouyang, Gangfeng

2015-01-01

Nanotechnology permits broad advances in agriculture. However, as it is still at a relatively early stage of development, the potential risks remain unclear. Herein, for the first time, we reveal the following: 1) the impact of multi-walled carbon nanotubes (MWCNTs) on the accumulation/depuration behaviors of contaminants in crop, mustard (Brassica juncea), and 2) the permeability and transportability of MWCNTs in intact mature mustard plants. Using an in vivo sampling technique, the kinetic accumulation/depuration processes of several contaminants in mustard plans exposed to MWCNTs were traced, and an enhancement of contaminant accumulation in living plants was observed. Meanwhile, we observed that the MWCNTs permeated into the roots of intact living plants (three months old) and were then transported to the upper organs under the force of transpiration steam. This study demonstrated that MWCNTs can act as contaminant carriers and be transported to the edible parts of crops. PMID:26498499

Membrane Transporters: Structure, Function and Targets for Drug Design

NASA Astrophysics Data System (ADS)

Ravna, Aina W.; Sager, Georg; Dahl, Svein G.; Sylte, Ingebrigt

Current therapeutic drugs act on four main types of molecular targets: enzymes, receptors, ion channels and transporters, among which a major part (60-70%) are membrane proteins. This review discusses the molecular structures and potential impact of membrane transporter proteins on new drug discovery. The three-dimensional (3D) molecular structure of a protein contains information about the active site and possible ligand binding, and about evolutionary relationships within the protein family. Transporters have a recognition site for a particular substrate, which may be used as a target for drugs inhibiting the transporter or acting as a false substrate. Three groups of transporters have particular interest as drug targets: the major facilitator superfamily, which includes almost 4000 different proteins transporting sugars, polyols, drugs, neurotransmitters, metabolites, amino acids, peptides, organic and inorganic anions and many other substrates; the ATP-binding cassette superfamily, which plays an important role in multidrug resistance in cancer chemotherapy; and the neurotransmitter:sodium symporter family, which includes the molecular targets for some of the most widely used psychotropic drugs. Recent technical advances have increased the number of known 3D structures of membrane transporters, and demonstrated that they form a divergent group of proteins with large conformational flexibility which facilitates transport of the substrate.

Using Iterative Plan-Do-Study-Act Cycles to Improve Teaching Pedagogy.

PubMed

Murray, Elizabeth J

2018-01-15

Most students entering nursing programs today are members of Generation Y or the Millennial generation, and they learn differently than previous generations. Nurse educators must consider implementing innovative teaching strategies that appeal to the newest generation of learners. The Plan-Do-Study-Act cycle is a framework that can be helpful when planning, assessing, and continually improving teaching pedagogy. This article describes the use of iterative Plan-Do-Study-Act cycles to implement a change in teaching pedagogy.

Integration of computational modeling with membrane transport studies reveals new insights into amino acid exchange transport mechanisms

PubMed Central

Widdows, Kate L.; Panitchob, Nuttanont; Crocker, Ian P.; Please, Colin P.; Hanson, Mark A.; Sibley, Colin P.; Johnstone, Edward D.; Sengers, Bram G.; Lewis, Rohan M.; Glazier, Jocelyn D.

2015-01-01

Uptake of system L amino acid substrates into isolated placental plasma membrane vesicles in the absence of opposing side amino acid (zero-trans uptake) is incompatible with the concept of obligatory exchange, where influx of amino acid is coupled to efflux. We therefore hypothesized that system L amino acid exchange transporters are not fully obligatory and/or that amino acids are initially present inside the vesicles. To address this, we combined computational modeling with vesicle transport assays and transporter localization studies to investigate the mechanisms mediating [14C]l-serine (a system L substrate) transport into human placental microvillous plasma membrane (MVM) vesicles. The carrier model provided a quantitative framework to test the 2 hypotheses that l-serine transport occurs by either obligate exchange or nonobligate exchange coupled with facilitated transport (mixed transport model). The computational model could only account for experimental [14C]l-serine uptake data when the transporter was not exclusively in exchange mode, best described by the mixed transport model. MVM vesicle isolates contained endogenous amino acids allowing for potential contribution to zero-trans uptake. Both L-type amino acid transporter (LAT)1 and LAT2 subtypes of system L were distributed to MVM, with l-serine transport attributed to LAT2. These findings suggest that exchange transporters do not function exclusively as obligate exchangers.—Widdows, K. L., Panitchob, N., Crocker, I. P., Please, C. P., Hanson, M. A., Sibley, C. P., Johnstone, E. D., Sengers, B. G., Lewis, R. M., Glazier, J. D. Integration of computational modeling with membrane transport studies reveals new insights into amino acid exchange transport mechanisms. PMID:25761365

Human Transportation System (HTS) study, volume 2

NASA Technical Reports Server (NTRS)

Lance, N.; Geyer, M. S.; Gaunce, M. T.

1993-01-01

This report summarizes work completed under the Human Transportation System Study. This study was conducted by the New Initiatives Office at JSC with the technical support of Boeing, General Dynamics, Lockheed, McDonnell-Douglas, Martin Marietta, and Rockwell. The study was designed to generate information on determining the appropriate path to follow for new system development to meet the Nation's space transportation needs. The study evaluates 18 transportation architecture options using a parametric set of mission requirements. These options include use of current systems (e.g., Shuttle, Titan, etc. ) as well as proposed systems (e.g., PLS, Single-Stage-to-Orbit, etc.) to assess the impact of various considerations, such as the cost of alternate access, or the benefit of separating people and cargo. The architecture options are compared to each other with six measurable evaluation criteria or attributes. They are: funding profile, human safety, probability of mission success, architecture cost risk, launch schedule confidence, and environmental impact. Values for these attributes are presented for the architecture options, with pertinent conclusions and recommendations.

Transportation workforce development and outreach seminars : CTME grant completion report.

DOT National Transportation Integrated Search

2011-01-03

The Safe, Accountable Flexible, Efficient Transportation Equity Act: A Legacy for Users (SAFETEA-LU) prescribes that the U.S. Secretary of Transportation shall issue guidelines and requirements for the reporting and evaluation of operational tests an...

76 FR 10594 - Ocean Transportation Intermediary License Revocation

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-25

... FEDERAL MARITIME COMMISSION Ocean Transportation Intermediary License Revocation The Federal Maritime Commission hereby gives notice that the following Ocean Transportation Intermediary licenses have been revoked pursuant to section 19 of the Shipping Act of 1984 (46 U.S.C. chapter 409) and the regulations of the Commission pertaining to the...

18 CFR 284.263 - Exemption from section 7 of Natural Gas Act and certain regulatory conditions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 7 of Natural Gas Act and certain regulatory conditions. 284.263 Section 284.263 Conservation of... UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Emergency Natural Gas Sale...

18 CFR 284.263 - Exemption from section 7 of Natural Gas Act and certain regulatory conditions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 7 of Natural Gas Act and certain regulatory conditions. 284.263 Section 284.263 Conservation of... UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES CERTAIN SALES AND TRANSPORTATION OF NATURAL GAS UNDER THE NATURAL GAS POLICY ACT OF 1978 AND RELATED AUTHORITIES Emergency Natural Gas Sale...

40 CFR 761.212 - Transporter compliance with the manifest.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) TOXIC SUBSTANCES CONTROL ACT POLYCHLORINATED BIPHENYLS (PCBs) MANUFACTURING, PROCESSING, DISTRIBUTION IN COMMERCE, AND USE PROHIBITIONS PCB Waste Disposal Records and Reports § 761.212 Transporter compliance with the manifest. (a) The transporter must deliver the entire quantity of PCB waste which he has accepted...

40 CFR 761.212 - Transporter compliance with the manifest.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) TOXIC SUBSTANCES CONTROL ACT POLYCHLORINATED BIPHENYLS (PCBs) MANUFACTURING, PROCESSING, DISTRIBUTION IN COMMERCE, AND USE PROHIBITIONS PCB Waste Disposal Records and Reports § 761.212 Transporter compliance with the manifest. (a) The transporter must deliver the entire quantity of PCB waste which he has accepted...

76 FR 11554 - Fiscal Year 2010 Public Transportation on Indian Reservations Program Project Selections

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-02

... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Fiscal Year 2010 Public Transportation... Interior for public transportation capital projects, operating costs and planning activities that are... authorized by the Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users...

Accessibility for the Handicapped: The Impact of Section 504 on Architectural and Transportation Barriers.

ERIC Educational Resources Information Center

Allbery, Charles Fred, III; Gressel, Michele

1978-01-01

Three federal acts--the Architectural Barriers Act, the Urban Mass Transportation Assistance Act, and the Rehabilitation Act of 1973--are the focus of this examination of federal efforts to remove physical barriers. Requirements, application, and remedies of the federal legislation and how each act relates to the others are considered. (AF)

Vadose Zone Transport Field Study: Summary Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ward, Andy L.; Conrad, Mark E.; Daily, William D.

2006-07-31

From FY 2000 through FY 2003, a series of vadose zone transport field experiments were conducted as part of the U.S. Department of Energy’s Groundwater/Vadose Zone Integration Project Science and Technology Project, now known as the Remediation and Closure Science Project, and managed by the Pacific Northwest National Laboratory (PNNL). The series of experiments included two major field campaigns, one at a 299-E24-11 injection test site near PUREX and a second at a clastic dike site off Army Loop Road. The goals of these experiments were to improve our understanding of vadose zone transport processes; to develop data sets tomore » validate and calibrate vadose zone flow and transport models; and to identify advanced monitoring techniques useful for evaluating flow-and-transport mechanisms and delineating contaminant plumes in the vadose zone at the Hanford Site. This report summarizes the key findings from the field studies and demonstrates how data collected from these studies are being used to improve conceptual models and develop numerical models of flow and transport in Hanford’s vadose zone. Results of these tests have led to a better understanding of the vadose zone. Fine-scale geologic heterogeneities, including grain fabric and lamination, were observed to have a strong effect on the large-scale behavior of contaminant plumes, primarily through increased lateral spreading resulting from anisotropy. Conceptual models have been updated to include lateral spreading and numerical models of unsaturated flow and transport have revised accordingly. A new robust model based on the concept of a connectivity tensor was developed to describe saturation-dependent anisotropy in strongly heterogeneous soils and has been incorporated into PNNL’s Subsurface Transport Over Multiple Phases (STOMP) simulator. Application to field-scale transport problems have led to a better understanding plume behavior at a number of sites where lateral spreading may have dominated

Study of aircraft in intraurban transportation systems

NASA Technical Reports Server (NTRS)

Stout, E. G.

1972-01-01

A systems analysis was conducted to define the technical economic and operational characteristics of an aircraft transportation system for short-range intracity commutor operations. The analysis was for 1975 and 1985 in the seven county, Detroit, Michigan area. STOL and VTOL aircraft were studied in sizes from 40 to 120 passengers. The preferred vehicle for the Detroit area was the deflected slipstream STOL. Since the study was parametric in nature, it is applicable to generalization, and it was concluded that a feasible intraurban air transportation system could be developed in many viable situations.

Transportation Community Institutional Infrastructure Study : Volume 1. National Transportation Needs Mail Survey.

DOT National Transportation Integrated Search

1976-04-01

The results of the Transportation Community Infrastructure Study are presented as a three volume series. This series presents a surveyed priority of topics for information exhange, a case study of a porposed training proram, and an analysis of the tr...

A CASE STUDY OF CHLORINE TRANSPORT AND FATE FOLLOWING A LARGE ACCIDENTAL RELEASE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buckley, R.; Hunter, C.; Werth, D.

2012-08-01

A train derailment that occurred in Graniteville, South Carolina during the early morning hours of 06 January, 2005 resulted in the prompt release of approximately 60 tons of chlorine to the environment. Comprehensive modeling of the transport and fate of this release was performed including the characterization of the initial three-phased chlorine release, a detailed determination of the local atmospheric conditions acting to generate, disperse, and deplete the chlorine vapor cloud, the establishment of physical exchange mechanisms between the airborne vapor and local surface waters, and local aquatic dilution and mixing.

28 CFR 79.62 - Criteria for eligibility for claims by ore transporters.

Code of Federal Regulations, 2012 CFR

2012-07-01

... ore transporters. 79.62 Section 79.62 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CLAIMS UNDER THE RADIATION EXPOSURE COMPENSATION ACT Eligibility Criteria for Claims by Ore Transporters § 79.62 Criteria for eligibility for claims by ore transporters. To establish eligibility for compensation...

28 CFR 79.62 - Criteria for eligibility for claims by ore transporters.

Code of Federal Regulations, 2011 CFR

2011-07-01

... ore transporters. 79.62 Section 79.62 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CLAIMS UNDER THE RADIATION EXPOSURE COMPENSATION ACT Eligibility Criteria for Claims by Ore Transporters § 79.62 Criteria for eligibility for claims by ore transporters. To establish eligibility for compensation...

28 CFR 79.62 - Criteria for eligibility for claims by ore transporters.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ore transporters. 79.62 Section 79.62 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CLAIMS UNDER THE RADIATION EXPOSURE COMPENSATION ACT Eligibility Criteria for Claims by Ore Transporters § 79.62 Criteria for eligibility for claims by ore transporters. To establish eligibility for compensation...

28 CFR 79.62 - Criteria for eligibility for claims by ore transporters.

Code of Federal Regulations, 2013 CFR

2013-07-01

... ore transporters. 79.62 Section 79.62 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CLAIMS UNDER THE RADIATION EXPOSURE COMPENSATION ACT Eligibility Criteria for Claims by Ore Transporters § 79.62 Criteria for eligibility for claims by ore transporters. To establish eligibility for compensation...

40 CFR 80.1460 - What acts are prohibited under the RFS program?

Code of Federal Regulations, 2011 CFR

2011-07-01

... with the RIN in an application other than for use as transportation fuel, jet fuel, or heating oil (as... associated with the RIN in an application other than for use as transportation fuel, jet fuel, or heating oil... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Renewable Fuel Standard § 80.1460 What acts are...

40 CFR 80.1460 - What acts are prohibited under the RFS program?

Code of Federal Regulations, 2013 CFR

2013-07-01

... application other than for use as transportation fuel, jet fuel, or heating oil (as defined in § 80.1401). (3... in an application other than for use as transportation fuel, jet fuel, or heating oil (as defined in... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Renewable Fuel Standard § 80.1460 What acts are...

40 CFR 80.1460 - What acts are prohibited under the RFS program?

Code of Federal Regulations, 2010 CFR

2010-07-01

... with the RIN in an application other than for use as transportation fuel, jet fuel, or heating oil (as... associated with the RIN in an application other than for use as transportation fuel, jet fuel, or heating oil... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Renewable Fuel Standard § 80.1460 What acts are...

40 CFR 80.1460 - What acts are prohibited under the RFS program?

Code of Federal Regulations, 2014 CFR

2014-07-01

... application other than for use as transportation fuel, jet fuel, or heating oil (as defined in § 80.1401). (3... in an application other than for use as transportation fuel, jet fuel, or heating oil (as defined in... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Renewable Fuel Standard § 80.1460 What acts are...

40 CFR 80.1460 - What acts are prohibited under the RFS program?

Code of Federal Regulations, 2012 CFR

2012-07-01

... application other than for use as transportation fuel, jet fuel, or heating oil (as defined in § 80.1401). (3... in an application other than for use as transportation fuel, jet fuel, or heating oil (as defined in... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Renewable Fuel Standard § 80.1460 What acts are...

18 CFR 284.267 - Intrastate pipeline emergency transportation rates.

Code of Federal Regulations, 2010 CFR

2010-04-01

... POLICY ACT OF 1978 AND RELATED AUTHORITIES Emergency Natural Gas Sale, Transportation, and Exchange... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Intrastate pipeline emergency transportation rates. 284.267 Section 284.267 Conservation of Power and Water Resources FEDERAL...

Hydrogen flammability limits and implications on fire safety of transportation vehicles

DOT National Transportation Integrated Search

2008-01-01

The recent establishment of the National University Transportation Center at MST under the "Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users," expands the research and education activities to include alternative tr...

Source tagging modeling study of heavy haze episodes under complex regional transport processes over Wuhan megacity, Central China.

PubMed

Lu, Miaomiao; Tang, Xiao; Wang, Zifa; Gbaguidi, Alex; Liang, Shengwen; Hu, Ke; Wu, Lin; Wu, Huangjian; Huang, Zhen; Shen, Longjiao

2017-12-01

Wuhan as a megacity of Central China was suffering from severe particulate matter pollution according to previous observation studies, however, the mechanism behind the pollution formation especially the impact of regional chemical transport is still unclear. This study, carried out on the Nested Air Quality Prediction Modeling System (NAQPMS) coupled with an on-line source-tagging module, explores different roles regional transport had in two strong haze episodes over Wuhan in October 2014 and quantitatively assesses the contributions from local and regional sources to PM 2.5 concentration. Validation of predictions based on observations shows modeling system good skills in reproducing key meteorological and chemical features. The first short-time haze episode occurred on 12 October under strong northerly winds, with a hourly PM 2.5 peak of 180 μg m -3 , and was found to be caused primarily by the long-range transport from the northern regions, which contributed 60.6% of the episode's PM 2.5 concentration (versus a total of 32.7% from sources in and near Wuhan). The second episode lasted from the 15-20 October under stable regional large-scale synoptic conditions and weak winds, and had an hourly PM 2.5 peak of 231.0 μg m -3 . In this episode, both the long-distance transport from far regions and short-range transport from the Wuhan-cluster were the primary causes of the haze episode and account for 24.8% and 29.2% of the PM 2.5 concentration respectively. Therefore, regional transport acts as a crucial driver of haze pollution over Wuhan through not only long-range transfer of pollutants, but also short-range aerosol movement under specific meteorological conditions. The present findings highlight the important role of regional transport in urban haze formation and indicate that the joint control of multi city-clusters are needed to reduce the particulate pollution level in Wuhan. Copyright © 2017 Elsevier Ltd. All rights reserved.

Hopewell Furnace NHS : alternative transportation study

DOT National Transportation Integrated Search

2009-12-31

This study assesses the potential for an alternative transportation system (ATS) at Hopewell Furnace National Historic Site (NHS). The Volpe Center investigated internal circulation and potential partnerships with local historic, cultural, and recrea...

The Americans with Disabilities Act: Implications for Camp Programming.

ERIC Educational Resources Information Center

Bedini, Leandra A.; And Others

1992-01-01

Discusses the effect of the Americans with Disabilities Act (ADA) on camp programing and provides strategies to improve camp accessibility for people with disabilities. Discusses obstacles to integrated programing including ecological and architectural barriers, attitudinal barriers, transportation barriers, barriers of omission, economic…

Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos

PubMed Central

2013-01-01

Background In mammals, ABCB1 constitutes a cellular “first line of defense” against a wide array of chemicals and drugs conferring cellular multidrug or multixenobiotic resistance (MDR/MXR). We tested the hypothesis that an ABCB1 ortholog serves as protection for the sensitive developmental processes in zebrafish embryos against adverse compounds dissolved in the water. Results Indication for ABCB1-type efflux counteracting the accumulation of chemicals in zebrafish embryos comes from experiments with fluorescent and toxic transporter substrates and inhibitors. With inhibitors present, levels of fluorescent dyes in embryo tissue and sensitivity of embryos to toxic substrates were generally elevated. We verified two predicted sequences from zebrafish, previously annotated as abcb1, by cloning; our synteny analyses, however, identified them as abcb4 and abcb5, respectively. The abcb1 gene is absent in the zebrafish genome and we explored whether instead Abcb4 and/or Abcb5 show toxicant defense properties. Quantitative real-time polymerase chain reaction (qPCR) analyses showed the presence of transcripts of both genes throughout the first 48 hours of zebrafish development. Similar to transporter inhibitors, morpholino knock-down of Abcb4 increased accumulation of fluorescent substrates in embryo tissue and sensitivity of embryos toward toxic compounds. In contrast, morpholino knock-down of Abcb5 did not exert this effect. ATPase assays with recombinant protein obtained with the baculovirus expression system confirmed that dye and toxic compounds act as substrates of zebrafish Abcb4 and inhibitors block its function. The compounds tested comprised model substrates of human ABCB1, namely the fluorescent dyes rhodamine B and calcein-am and the toxic compounds vinblastine, vincristine and doxorubicin; cyclosporin A, PSC833, MK571 and verapamil were applied as inhibitors. Additionally, tests were performed with ecotoxicologically relevant compounds: phenanthrene (a

Low-impact, high toughness transportation barriers.

DOT National Transportation Integrated Search

2012-10-01

Alternatives to existing transportation truck escape ramps and crash barriers are examined using arrays of : wood, bamboo, and fiberglass structural elements that act as energy absorbers as they deform. The : behaviors of each material type are analy...

General Information for Transportation and Conformity

EPA Pesticide Factsheets

Transportation conformity is required by the Clean Air Act section 176(c) (42 U.S.C. 7506(c)) to ensure that federal funding and approval are given to highway and transit projects that are consistent with SIP.

1994 Transportation/ Air Quality Conformity Finding

DOT National Transportation Integrated Search

1993-10-01

The purpose of this report is to document the finding that the transportation : plans and programs for the Albuquerque Metropolitan Planning Area (AMPA) are in : conformity with the applicable Clean Air Act implementation plans for the : nonattainmen...

A Case Study: An ACT Stress Management Group in a University Counseling Center

ERIC Educational Resources Information Center

Daltry, Rachel M.

2015-01-01

The aim of this study was to examine the effectiveness of an acceptance and commitment therapy (ACT) stress management group in a college counseling center setting. This study explored (a) the effectiveness of ACT in increasing participants' ability to tolerate distress, which directly affects their ability to function in a stressful college…

Comparative divertor-transport study for helical devices

NASA Astrophysics Data System (ADS)

Feng, Y.; Kobayashi, M.; Sardei, F.; Masuzaki, S.; Kisslinger, J.; Morisaki, T.; Grigull, P.; Yamada, H.; McCormick, K.; Ohyabu, N.; König, R.; Yamada, I.; Giannone, L.; Narihara, K.; Wenzel, U.; Morita, S.; Thomsen, H.; Miyazawa, J.; Hildebrandt, D.; Watanabe, T.; Wagner, F.; Ashikawa, N.; Ida, K.; Komori, A.; Motojima, O.; Nakamura, Y.; Peterson, B. J.; Sato, K.; Shoji, M.; Tamura, N.; Tokitani, M.; LHD experimental Group

2009-09-01

Using the island divertors (IDs) of W7-AS and W7-X and the helical divertor (HD) of LHD as examples, the paper presents a comparative divertor transport study for three typical helical devices of different machine sizes following two distinct divertor concepts, aiming at identifying common physics issues/effects for mutual validation and combined studies. Based on EMC3/EIRENE simulations supported by experimental results, the paper first reviews and compares the essential transport features of the W7-AS ID and the LHD HD in order to build a base and framework for a predictive study of W7-X. The fundamental role of low-order magnetic islands in both divertor concepts is emphasized. Preliminary EMC3/EIRENE simulation results for W7-X are presented and discussed with respect to W7-AS and LHD in order to show how the individual field and divertor topologies affect the divertor transport and performance. For instance, a high recycling regime, which is absent from W7-AS and LHD, is predicted to exist for W7-X. The paper focuses on identifying and understanding the role of divertors for high density plasma operations in helical devices. In this regard, special attention is paid to investigating the divertor function for controlling intrinsic impurities. Impurity transport behaviour and wall-sputtering processes of CX-neutrals are studied under different divertor plasma conditions. A divertor retention effect on intrinsic impurities at high SOL collisonalities is predicted for all the three devices. The required SOL plasma conditions and the underlying mechanisms are analysed in detail. Numerical results are discussed in conjunction with the experimental observations for high density divertor plasmas in W7-AS and LHD. Different SOL transport regimes are numerically identified for the standard divertor configuration of W7-X and the possible consequences on high density plasmas are assessed. All the EMC3-EIRENE simulations presented in this paper are based on vacuum fields

75 FR 49435 - Transportation Conformity Rule Restructuring Amendments

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-13

... transportation plans, programs, or projects under title 23 U.S.C. or title 49 U.S.C. chapter 53. Regulated... for copying docket materials. C. How do I get copies of this proposed rule and other documents? 1... Clean Air Act (CAA) section 176(c) (42 U.S.C. 7506(c)) to ensure that transportation plans...

Applying the plan-do-study-act model to increase the use of kangaroo care.

PubMed

Stikes, Reetta; Barbier, Denise

2013-01-01

To increase the rate of participation in kangaroo care within a level III neonatal intensive care unit. Preterm birth typically results in initial separation of mother and infant which may disrupt the bonding process. Nurses within the neonatal intensive care unit can introduce strategies that will assist parents in overcoming fears and developing relationships with their infants. Kangaroo care is a method of skin-to-skin holding that has been shown to enhance the mother-infant relationship while also improving infant outcomes. However, kangaroo care has been used inconsistently within neonatal intensive care unit settings. The Plan-Do-Study-Act Model was used as a framework for this project. Plan-Do-Study-Act Model uses four cyclical steps for continuous quality improvement. Based upon Plan-Do-Study-Act Model, education was planned, surveys were developed and strategies implemented to overcome barriers. Four months post-implementation, the use of kangaroo care increased by 31%. Staff surveys demonstrated a decrease in the perceived barriers to kangaroo care as well as an increase in kangaroo care. Application of Plan-Do-Study-Act Model was successful in meeting the goal of increasing the use of kangaroo care. The use of the Plan-Do-Study-Act Model framework encourages learning, reflection and validation throughout implementation. Plan-Do-Study-Act Model is a strategy that can promote the effective use of innovative practices in nursing. © 2013 Blackwell Publishing Ltd.

78 FR 19357 - Allocation of Public Transportation Emergency Relief Funds in Response to Hurricane Sandy

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-29

... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Allocation of Public Transportation...) announces the allocation of $2,000,000,000 under the Public Transportation Emergency Relief Program... after an emergency or major disaster that affects public transportation systems. The Appropriations Act...

Glycine Transporters and Their Inhibitors

NASA Astrophysics Data System (ADS)

Gilfillan, Robert; Kerr, Jennifer; Walker, Glenn; Wishart, Grant

Glycine plays a ubiquitous role in many biological processes. In the central nervous system it serves as an important neurotransmitter acting as an agonist at strychnine-sensitive glycine receptors and as an essential co-agonist with glutamate at the NMDA receptor complex. Control of glycine concentrations in the vicinity of these receptors is mediated by the specific glycine transporters, GlyT1 and GlyT2. Inhibition of these transporters has been postulated to be of potential benefit in several therapeutic indications including schizophrenia and pain. In this review we discuss our current knowledge of glycine transporters and focus on recent advances in the medicinal chemistry of GlyT1 and GlyT2 inhibitors.

23 CFR 450.212 - Transportation planning studies and project development.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Transportation planning studies and project development. 450.212 Section 450.212 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Statewide Transportation Planning and Programming § 450...

Resolving the Mystery of Transport Within Internal Transport Barriers

NASA Astrophysics Data System (ADS)

Staebler, G. M.

2013-10-01

The Trapped Gyro-Landau Fluid (TGLF) quasilinear model, which is calibrated to approximate non-linear gyro-kinetic turbulence simulations, is now able to predict the electron density, electron and ion temperatures and ion toroidal rotation simultaneously for internal transport barrier (ITB) discharges in excellent agreement with data from the DIII-D tokamak. This is a strong validation of gyro-kinetic theory of ITBs, requiring multiple instabilities responsible for transport in different channels at different scales. Inside the ITB, the ion energy transport is observed to be reduced to the neoclassical level which is consistent with the theory of turbulence suppression by E × B velocity shear acting on low wavenumber turbulence. The electron energy transport is observed to be far above the neoclassical level which is consistent with electron energy transport due to high wavenumber electron temperature gradient (ETG) modes. Since the ETG modes do not produce particle and ion momentum transport, and low wavenumber modes are suppressed, these channels are expected to be reduced to the neoclassical level in striking disagreement with experimental measurements. A possible resolution of this conundrum was found in 2005 when gyro-kinetic turbulence simulations showed that the parallel velocity shear driven Kelvin-Helmholtz (KH) mode can arrest the suppression of transport by the shear in the E × B velocity Doppler shift at high toroidal flow shear. The success of TGLF in predicting ITB transport is due to the inclusion of ion gyro-radius scale modes that become dominant at high E × B shear and to recent improvements to TGLF that allow the KH mode to be faithfully modeled. The resolution of this long-standing mystery of the missing particle and momentum transport in an ITB is the result of the steady advances in gyro-kinetic simulations and quasilinear modeling. Supported by the US Department of Energy under DE-FG02-95ER54309.

Calculations of Electron Transport through Radicals

NASA Astrophysics Data System (ADS)

Smeu, Manuel; Dilabio, Gino

2010-03-01

Organic radicals are of interest in molecular electronics because a singly occupied molecular orbital (SOMO) would have a higher energy than its doubly occupied analog, suggesting they might make better conductors. The unpaired electron present in a radical leads to degeneracy splitting in other energy levels and such molecules may act as spin filters. Our study employs first principles transport calculations that are performed using a combination of density functional theory and a non-equilibrium Green's function technique. The conductance of 1,4-benzenediamine (BDA) molecules bridging two Au electrodes was modeled. These molecules were substituted in the 2-position with: -CH3, -NH2, and -OH; as well as with their radical analogs: -CH2, -NH, and -O, all of which have π-type SOMOs. The conductance of a radical with a σ-type SOMO was also calculated from a BDA molecule with the H atom in the 2-position removed. Comparing the transmission spectra for these species will yield insight into the nature of electron transport through radicals vs. transport through their reduced form as well as the nature of transport through π- and σ-type molecular orbitals.

Fort McHenry alternative transportation study

DOT National Transportation Integrated Search

2004-06-01

This project assesses transportation management issues at Fort McHenry National Monument and Historic Shrine in the Locust Point area of Baltimore. Goals of the study include mitigating traffic congestion and idling of school or tour buses, encouragi...

Experimental evaluation of the significance of the pressure transport term for the Turbulence Kinetic Energy Budget across contrasting forest architectures

NASA Astrophysics Data System (ADS)

Ehrnsperger, Laura; Wunder, Tobias; Thomas, Christoph

2017-04-01

Forests are one of the dominant vegetation types on Earth and are an important sink for carbon on our planet. Forests are special ecosystems due to their great canopy height und complex architecture consisting of a subcanopy and a canopy layer, which changes the mechanisms of turbulent exchange within the plant canopy. To date, the sinks and sources of turbulence in forest canopies are not completely understood, especially the role of the pressure transport remains unclear. The INTRAMIX experiment was conducted in a mountainous Norway spruce (Picea abies) forest at the Fluxnet Waldstein site (DE-Bay) in Bavaria, Germany, for a period of 10 weeks in order to experimentally evaluate the significance of the pressure transport to the TKE budget for the first time. The INTRAMIX data of the dense mountain forest was compared to observations from a sparse Ponderosa pine (Pinus ponderosa) stand in Oregon, USA, to study the influence of forest architecture. We hypothesized that the pressure transport is more important in dense forest canopies as the crown decouples the subcanopy from the buoyancy- and shear-driven flow above the canopy. It is also investigated how atmospheric stability influences the TKE budget. Based upon model results from literature we expect the pressure transport to act as a source for TKE especially under free convective and unstable dynamic stability. Results to date indicate that pressure transport is most important in the subcanopy with decreasing magnitude with increasing height. Nevertheless, pressure transport is a continuous source of TKE above the canopy, while in the canopy and subcanopy layer pressure transport acts both as a sink and source term for TKE. In the tree crown layer pressure transport is a source in the morning and afternoon hours and acts as a sink during the evening, while in the subcanopy pressure transport is a source around noon and during the night and acts as a sink in the early morning and afternoon hours. This

Howard Coble Coast Guard and Maritime Transportation Act of 2014

THOMAS, 113th Congress

Rep. Hunter, Duncan D. [R-CA-50

2014-12-01

Senate - 12/04/2014 Received in the Senate and Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Notes: For further action, see S.2444, which became Public Law 113-281 on 12/18/2014. Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

The Costs and Challenges of Transporting Students with Disabilities

ERIC Educational Resources Information Center

Suttman, Craig M.

2009-01-01

Federal law does not require school boards to provide transportation for all students. But the Individuals with Disabilities Education Act (IDEA) entitles students with disabilities to transportation to and from school if the students' disabilities make it difficult for them to get to school; from, in, and around the buildings where they attend…

78 FR 14153 - Advisory Council on Transportation Statistics; Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-04

... Transportation Statistics; Meeting AGENCY: Research and Innovative Technology Administration (RITA), DOT. ACTION... Statistics (ACTS). The meeting was scheduled for Monday, March 4, 2013 from 8:30 a.m. to 4:00 p.m. E.S.T. in...., Washington, DC. The Bureau of Transportation Statistics (BTS) will reschedule the meeting for a future date...

Natural products from Pluchea sagittalis act as inhibitors of photosynthesis in vitro.

PubMed

Carvalho, Ana C; Lira, João C S; Pereira, Thaís M; Silva, Sebastião C; Simote-Silva, Simone Y; Oliveira, Fernando K D; King-Diaz, Beatriz; Lotina-Hennsen, Blas; Veiga, Thiago A M

2017-10-31

Four compounds were isolated from roots and aerial parts of Pluchea sagittalis (Asteraceae), 3, 5-dihydroxy-6, 7, 3', 4'-tetramethoxiflavunol (1), 5-hydroxymethylfurfural (2), 3, 4-dimethoxybenzaldehyde (3) and 2, 3, 4-trihydroxybenzaldeyde (4). Their herbicidal potential was detected by polarographic techniques. All of them inhibited the non-cyclic electron transport on basal, phosphorylating and uncoupled conditions from H 2 O to methylviologen (MV); thus, they act as Hill reaction inhibitors. Studies on fluorescence of chlorophyll a (ChL a) indicated they have different modes of interaction and inhibition sites on the photosystem II electron transport chain; 1-3 have interacted with the acceptor side while 4 has interacted at the donor side.

Active transportation measurement : Minneapolis case study.

DOT National Transportation Integrated Search

2013-06-01

This research examines longitudinal bicycle count data to better understand the impact of new bicycle facilities on use. The study site is Minneapolis which has invested close to $25 million over 8 years to improve active transportation facilities as...

Nantucket National Wildlife Refuge alternative transportation study

DOT National Transportation Integrated Search

2014-10-01

This study for the Fish and Wildlife Service (FWS) identifies and analyzes options for enhancing alternative transportation access to the Nantucket National Wildlife Refuge (Nantucket NWR) at Great Point in Nantucket, Massachusetts. The study team de...

Integrated mass transportation system study/definition/implementation program definition

NASA Technical Reports Server (NTRS)

Ransone, R. K.; Deptula, D. A.; Yorke, G. G.

1975-01-01

Specific actions needed to plan and effect transportation system improvements are identified within the constraints of limited financial, energy and land use resources, and diverse community requirements. A specific program is described which would develop the necessary generalized methodology for devising improved transportation systems and evaluate them against specific criteria for intermodal and intramodal optimization. A consistent, generalized method is provided for study and evaluation of transportation system improvements.

Spin-Dependent Transport through Chiral Molecules Studied by Spin-Dependent Electrochemistry

PubMed Central

2016-01-01

Conspectus Molecular spintronics (spin + electronics), which aims to exploit both the spin degree of freedom and the electron charge in molecular devices, has recently received massive attention. Our recent experiments on molecular spintronics employ chiral molecules which have the unexpected property of acting as spin filters, by way of an effect we call “chiral-induced spin selectivity” (CISS). In this Account, we discuss new types of spin-dependent electrochemistry measurements and their use to probe the spin-dependent charge transport properties of nonmagnetic chiral conductive polymers and biomolecules, such as oligopeptides, L/D cysteine, cytochrome c, bacteriorhodopsin (bR), and oligopeptide-CdSe nanoparticles (NPs) hybrid structures. Spin-dependent electrochemical measurements were carried out by employing ferromagnetic electrodes modified with chiral molecules used as the working electrode. Redox probes were used either in solution or when directly attached to the ferromagnetic electrodes. During the electrochemical measurements, the ferromagnetic electrode was magnetized either with its magnetic moment pointing “UP” or “DOWN” using a permanent magnet (H = 0.5 T), placed underneath the chemically modified ferromagnetic electrodes. The spin polarization of the current was found to be in the range of 5–30%, even in the case of small chiral molecules. Chiral films of the l- and d-cysteine tethered with a redox-active dye, toludin blue O, show spin polarizarion that depends on the chirality. Because the nickel electrodes are susceptible to corrosion, we explored the effect of coating them with a thin gold overlayer. The effect of the gold layer on the spin polarization of the electrons ejected from the electrode was investigated. In addition, the role of the structure of the protein on the spin selective transport was also studied as a function of bias voltage and the effect of protein denaturation was revealed. In addition to �

Commuter Benefits Provisions of the Taxpayer Relief Act of 1997

DOT National Transportation Integrated Search

1997-08-22

The Taxpayer Relief Act of 1997 makes offering a menu of commute benefits, sometimes called transportation fringe benefits, far more appealing to employers. Downtown employers and their employees are most likely to take advantage of the new tax law p...

ACT-CCREC Core Research Program: Study Questions and Design. ACT Working Paper Series. WP-2015-01

ERIC Educational Resources Information Center

Cruce, Ty M.

2015-01-01

This report provides a non-technical overview of the guiding research questions and research design for the ACT-led core research program conducted on behalf of the GEAR UP College and Career Readiness Evaluation Consortium (CCREC). The core research program is a longitudinal study of the effectiveness of 14 GEAR UP state grants on the academic…

Water transport across biological membranes: Overton, water channels, and peritoneal dialysis.

PubMed

Devuyst, O

2010-01-01

Peritoneal dialysis involves diffusive and convective transports and osmosis through the highly vascularized peritoneal membrane. Several lines of evidence have demonstrated that the water channel aquaporin-1 (AQP1) corresponds to the ultrasmall pore predicted by the modelization of peritoneal transport. Proof-of-principle studies have shown that upregulation of the expression of AQP1 in peritoneal capillaries is reflected by increased water permeability and ultrafiltration, without affecting the osmotic gradient and the permeability for small solutes. Inversely, studies in Aqp1 mice have shown that haplo-insufficiency in AQP1 is reflected by significant attenuation of water transport. Recent studies have identified lead compounds that could act as agonists of aquaporins, as well as putative binding sites and potential mechanisms of gating the water channel. By modulating water transport, these pharmacological agents could have clinically relevant effects in targeting specific tissues or disease states. These studies on the peritoneal membrane also provide an experimental framework to investigate the role of water channels in the endothelium and various cell types.

Safety Hazards During Intrahospital Transport: A Prospective Observational Study.

PubMed

Bergman, Lina M; Pettersson, Monica E; Chaboyer, Wendy P; Carlström, Eric D; Ringdal, Mona L

2017-10-01

To identify, classify, and describe safety hazards during the process of intrahospital transport of critically ill patients. A prospective observational study. Data from participant observations of the intrahospital transport process were collected over a period of 3 months. The study was undertaken at two ICUs in one university hospital. Critically ill patients transported within the hospital by critical care nurses, unlicensed nurses, and physicians. None. Content analysis was performed using deductive and inductive approaches. We detected a total of 365 safety hazards (median, 7; interquartile range, 4-10) during 51 intrahospital transports of critically ill patients, 80% of whom were mechanically ventilated. The majority of detected safety hazards were assessed as increasing the risk of harm, compromising patient safety (n = 204). Using the System Engineering Initiative for Patient Safety, we identified safety hazards related to the work system, as follows: team (n = 61), tasks (n = 83), tools and technologies (n = 124), environment (n = 48), and organization (n = 49). Inductive analysis provided an in-depth description of those safety hazards, contributing factors, and process-related outcomes. Findings suggest that intrahospital transport is a hazardous process for critically ill patients. We have identified several factors that may contribute to transport-related adverse events, which will provide the opportunity for the redesign of systems to enhance patient safety.

Stark County Area Transportation Study - Transportation Improvement Program 1997-2000

DOT National Transportation Integrated Search

1996-05-01

The Transportation Improvement Program (TIP) is the schedule of highway and transit improvements recommended for implementation within the next four years. It is, therefore, the end product of the transportation planning process. The TIP originates f...

75 FR 37873 - Notice of Funding Availability for the Department of Transportation's National Infrastructure...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-30

... Investments Under the Transportation, Housing and Urban Development, and Related Agencies Appropriations Act... grant program under the FY 2010 Appropriations Act. The DOT is referring to the grants for National... FY 2010 Appropriations Act, the DOT will evaluate all applications and announce the projects that...

Mechanistic Study of Human Glucose Transport Mediated by GLUT1.

PubMed

Fu, Xuegang; Zhang, Gang; Liu, Ran; Wei, Jing; Zhang-Negrerie, Daisy; Jian, Xiaodong; Gao, Qingzhi

2016-03-28

The glucose transporter 1 (GLUT1) belongs to the major facilitator superfamily (MFS) and is responsible for the constant uptake of glucose. However, the molecular mechanism of sugar transport remains obscure. In this study, homology modeling and molecular dynamics (MD) simulations in lipid bilayers were performed to investigate the combination of the alternate and multisite transport mechanism of glucose with GLUT1 in atomic detail. To explore the substrate recognition mechanism, the outward-open state human GLUT1 homology model was generated based on the template of xylose transporter XylE (PDB ID: 4GBZ), which shares up to 29% sequence identity and 49% similarity with GLUT1. Through the MD simulation study of glucose across lipid bilayer with both the outward-open GLUT1 and the GLUT1 inward-open crystal structure, we investigated six different conformational states and identified four key binding sites in both exofacial and endofacial loops that are essential for glucose recognition and transport. The study further revealed that four flexible gates consisting of W65/Y292/Y293-M420/TM10b-W388 might play important roles in the transport cycle. The study showed that some side chains close to the central ligand binding site underwent larger position changes. These conformational interchanges formed gated networks within an S-shaped central channel that permitted staged ligand diffusion across the transporter. This study provides new inroads for the understanding of GLUT1 ligand recognition paradigm and configurational features which are important for molecular, structural, and physiological research of the MFS members, especially for GLUT1-targeted drug design and discovery.

American Indian transportation : issues and successful models

DOT National Transportation Integrated Search

2006-01-01

Part I of this brief will identify issues, funding opportunities under the reauthorized national transit law Safe Accountable, Flexible, Efficient Transportation Equity Act a Legacy for Users (SAFETEA-LU), and benefits of investing in tribal tran...

A Study of Vertical Transport through Graphene toward Control of Quantum Tunneling.

PubMed

Zhu, Xiaodan; Lei, Sidong; Tsai, Shin-Hung; Zhang, Xiang; Liu, Jun; Yin, Gen; Tang, Min; Torres, Carlos M; Navabi, Aryan; Jin, Zehua; Tsai, Shiao-Po; Qasem, Hussam; Wang, Yong; Vajtai, Robert; Lake, Roger K; Ajayan, Pulickel M; Wang, Kang L

2018-02-14

Vertical integration of van der Waals (vdW) materials with atomic precision is an intriguing possibility brought forward by these two-dimensional (2D) materials. Essential to the design and analysis of these structures is a fundamental understanding of the vertical transport of charge carriers into and across vdW materials, yet little has been done in this area. In this report, we explore the important roles of single layer graphene in the vertical tunneling process as a tunneling barrier. Although a semimetal in the lateral lattice plane, graphene together with the vdW gap act as a tunneling barrier that is nearly transparent to the vertically tunneling electrons due to its atomic thickness and the transverse momenta mismatch between the injected electrons and the graphene band structure. This is accentuated using electron tunneling spectroscopy (ETS) showing a lack of features corresponding to the Dirac cone band structure. Meanwhile, the graphene acts as a lateral conductor through which the potential and charge distribution across the tunneling barrier can be tuned. These unique properties make graphene an excellent 2D atomic grid, transparent to charge carriers, and yet can control the carrier flux via the electrical potential. A new model on the quantum capacitance's effect on vertical tunneling is developed to further elucidate the role of graphene in modulating the tunneling process. This work may serve as a general guideline for the design and analysis of vdW vertical tunneling devices and heterostructures, as well as the study of electron/spin injection through and into vdW materials.

In vitro study of LDL transport under pressurized (convective) conditions.

PubMed

Cancel, Limary M; Fitting, Andrew; Tarbell, John M

2007-07-01

It is difficult to assess the transport pathways that carry low-density lipoprotein (LDL) into the artery wall in vivo, and there has been no previous in vitro study that has examined transendothelial transport under physiologically relevant pressurized (convective) conditions. Therefore, we measured water, albumin, and LDL fluxes across bovine aortic endothelial cell (BAEC) monolayers in vitro and determined the relative contributions of vesicles, paracellular transport through "breaks" in the tight junction, and "leaky" junctions associated with dying or dividing cells. Our results show that leaky junctions are the dominant pathway for LDL transport (>90%) under convective conditions and that albumin also has a significant component of transport through leaky junctions (44%). Transcellular transport of LDL by receptor-mediated processes makes a minor contribution (<10%) to overall transport under convective conditions.

49 CFR 229.7 - Prohibited acts and penalties.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., or has caused death or injury, a penalty not to exceed $105,000 per violation may be assessed. Each... 49 Transportation 4 2014-10-01 2014-10-01 false Prohibited acts and penalties. 229.7 Section 229.7... penalties. (a) Federal Rail Safety Laws (49 U.S.C. 20701-20703) make it unlawful for any carrier to use or...

49 CFR 229.7 - Prohibited acts and penalties.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., or has caused death or injury, a penalty not to exceed $105,000 per violation may be assessed. Each... 49 Transportation 4 2013-10-01 2013-10-01 false Prohibited acts and penalties. 229.7 Section 229.7... penalties. (a) Federal Rail Safety Laws (49 U.S.C. 20701-20703) make it unlawful for any carrier to use or...

49 CFR 229.7 - Prohibited acts and penalties.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., or has caused death or injury, a penalty not to exceed $105,000 per violation may be assessed. Each... 49 Transportation 4 2012-10-01 2012-10-01 false Prohibited acts and penalties. 229.7 Section 229.7... penalties. (a) Federal Rail Safety Laws (49 U.S.C. 20701-20703) make it unlawful for any carrier to use or...

78 FR 53712 - Surface Transportation Project Delivery Program Application Requirements

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-30

... the 21st Century Act (MAP-21), which converted the Surface Transportation Project Delivery Pilot... signed into law the Moving Ahead for Progress in the 21st Century Act (MAP-21), Public Law 112-141, 126... days from the date of MAP-21's enactment (October 1, 2012)--the regulations concerning the information...

41 CFR 102-117.135 - What are the international transportation restrictions?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Fly America Act (International Air Transportation Fair Competitive Practices Act of 1974) (49 U.S.C. 40118); and (b) International movement of property by water is subject to the cargo preference laws (see... service is available. The Maritime Administration (MARAD) monitors agency compliance of these laws. All...

78 FR 26845 - Privacy Act of 1974; Department of Transportation, Office of the Secretary of Transportation; DOT...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-08

..., to collect and maintain biographical information of Department of Transportation employees and other... information, including photographs, of senior leadership, employees and others who are engaged in activities... the qualifications of the Department's employees, contractors, or others about whom the Department...

Center for Transportation Studies 24th annual transportation research conference, May 22-23, 2013, Saint Paul, Minnesota.

DOT National Transportation Integrated Search

2013-05-01

The University of Minnesotas Center for Transportation : Studies is pleased to present its 24th Annual Transportation : Research Conference, May 22-23, 2013. The conference will : be held at the Saint Paul RiverCentre, 175 West Kellogg : Boulevard...

QUIT EMR trial: a prospective, observational, multicentre study to evaluate quality and 24 hours post-transport morbidity of interhospital transportation of critically ill patients: study protocol.

PubMed

Strauch, Ulrich; Bergmans, Dennis C J J; Habers, Joachim; Jansen, Jochen; Winkens, Bjorn; Veldman, Dirk J; Roekaerts, Paul M H J; Beckers, Stefan K

2017-03-10

It is widely accepted that transportation of critically ill patients is high risk. Unfortunately, however, there are currently no evidence-based criteria with which to determine the quality of various interhospital transport systems and their impact on the outcomes for patients. We aim to rectify this by assessing 2 scores which were developed in our hospital in a prospective, observational study. Primarily, we will be examining the Quality of interhospital critical care transportation in the Euregion Meuse-Rhine (QUIT EMR) score, which focuses on the quality of the transport system, and secondarily the SEMROS (Simplified EMR outcome score) which detects changes in the patient's clinical condition in the 24 hours following their transportation. A web-based application will be used to document around 150 pretransport, intratransport and post-transport items of each patient case.To be included, patients must be at least 18-years of age and should have been supervised by a physician during an interhospital transport which was started in the study region.The quality of the QUIT EMR score will be assessed by comparing 3 predefined levels of transport facilities: the high, medium and low standards. Subsequently, SEMROS will be used to determine the effect of transport quality on the morbidity 24 hours after transportation.It is estimated that there will be roughly 3000 appropriate cases suitable for inclusion in this study per year. Cases shall be collected from 1 April 2015 until 31 December 2017. This trial was approved by the Ethics committees of the university hospitals of Maastricht (Netherlands) and Aachen (Germany). The study results will be published in a peer reviewed journal. Results of this study will determine if a prospective randomised trial involving patients of various categories being randomly assigned to different levels of transportation system shall be conducted. NTR4937. Published by the BMJ Publishing Group Limited. For permission to use (where

Evaluation of low wing-loading fuel conservative, short-haul transports

NASA Technical Reports Server (NTRS)

Pasley, L. H.; Waldeck, T. A.

1976-01-01

Fuel conservation that could be attained with two technology advancements, Q fan propulsion system and active control technology (ACT) was studied. Aircraft incorporating each technology were sized for a Federal Aviation Regulation (FAR) field length of 914 meters (3,000 feet), 148 passengers, and a 926 kilometer (500 nautical mile) mission. The cruise Mach number was .70 at 10100 meter (33,000 foot) altitude. The improvement resulting from application of the Q fan propulsion system was computed relative to an optimized fuel conservative transport design. The performance improvements resulting from application of ACT technology were relative to the optimized Q fan propulsion system configuration.

Public transportation : New Starts program challenges and preliminary observations on expediting project development.

DOT National Transportation Integrated Search

2009-06-01

The New Starts program is an : important source of new capital : investment in mass transportation. : As required by the Safe, : Accountable, Flexible, Efficient : Transportation Equity Act: A : Legacy for Users, the Federal : Transit Administration ...

One-dimensional potential of mean force underestimates activation barrier for transport across flexible lipid membranes

NASA Astrophysics Data System (ADS)

Kopelevich, Dmitry I.

2013-10-01

Transport of a fullerene-like nanoparticle across a lipid bilayer is investigated by coarse-grained molecular dynamics (MD) simulations. Potentials of mean force (PMF) acting on the nanoparticle in a flexible bilayer suspended in water and a bilayer restrained to a flat surface are computed by constrained MD simulations. The rate of the nanoparticle transport into the bilayer interior is predicted using one-dimensional Langevin models based on these PMFs. The predictions are compared with the transport rates obtained from a series of direct (unconstrained) MD simulations of the solute transport into the flexible bilayer. It is observed that the PMF acting on the solute in the flexible membrane underestimates the transport rate by more than an order of magnitude while the PMF acting on the solute in the restrained membrane yields an accurate estimate of the activation energy for transport into the flexible membrane. This paradox is explained by a coexistence of metastable membrane configurations for a range of the solute positions inside and near the flexible membrane. This leads to a significant reduction of the contribution of the transition state to the mean force acting on the solute. Restraining the membrane shape ensures that there is only one stable membrane configuration corresponding to each solute position and thus the transition state is adequately represented in the PMF. This mechanism is quite general and thus this phenomenon is expected to occur in a wide range of interfacial systems. A simple model for the free energy landscape of the coupled solute-membrane system is proposed and validated. This model explicitly accounts for effects of the membrane deformations on the solute transport and yields an accurate prediction of the activation energy for the solute transport.

Tools for studying drug transport and metabolism in the brain.

PubMed

Pitcher, Meagan R; Quevedo, João

2016-01-01

Development of xenobiotics that cross the blood-brain barrier in therapeutically-relevant quantities is an expensive and time-consuming undertaking. However, central nervous system diseases are an under-addressed cause of high mortality and morbidity, and drug development in this field is a worthwhile venture. We aim to familiarize the reader with available methodologies for studying drug transport into the brain. Current understanding of the blood-brain barrier structure has been well-described in other manuscripts, and first we briefly review the path that xenobiotics take through the brain - from bloodstream, to endothelial cells of the blood-brain barrier, to interstitial space, to brain parenchymal cells, and then to an exit point from the central nervous system. The second half of the review discusses research tools available to determine if xenobiotics are making the journey through the brain successfully and offers commentary on the translational utility of each methodology. Theoretically, non-human mammalian and human blood-brain barriers are similar in composition; however, some findings demonstrate important differences across species. Translational methodologies may provide more reliable information about how a drug may act across species. The recent finding of lymphatic vessels within the central nervous system may provide new tools and strategies for drug delivery to the brain.

Evaluation of intelligent transportation infrastructure program (ITIP) in Pittsburgh and Philadelphia, Pennsylvania

DOT National Transportation Integrated Search

2003-03-20

The Transportation Equity Act for the 21st Century (TEA-21) Public Laws 105-178 and 105-206, Title V, Section 5117(b) (3) provides for an Intelligent Transportation Infrastructure Program (ITIP) to advance the deployment of operational intelligent tr...

Beyond the Byrd Road Act : VDOT's relationship with Virginia's urban counties.

DOT National Transportation Integrated Search

1998-01-01

Since the Byrd Road Act of 1932, the Virginia Department of Transportation (VDOT) has been responsible for secondary road maintenance and construction in all of the state's counties except two (Arlington and Henrico). Such an arrangement is unusual a...

Rotation of endosomes demonstrates coordination of molecular motors during axonal transport.

PubMed

Kaplan, Luke; Ierokomos, Athena; Chowdary, Praveen; Bryant, Zev; Cui, Bianxiao

2018-03-01

Long-distance axonal transport is critical to the maintenance and function of neurons. Robust transport is ensured by the coordinated activities of multiple molecular motors acting in a team. Conventional live-cell imaging techniques used in axonal transport studies detect this activity by visualizing the translational dynamics of a cargo. However, translational measurements are insensitive to torques induced by motor activities. By using gold nanorods and multichannel polarization microscopy, we simultaneously measure the rotational and translational dynamics for thousands of axonally transported endosomes. We find that the rotational dynamics of an endosome provide complementary information regarding molecular motor activities to the conventionally tracked translational dynamics. Rotational dynamics correlate with translational dynamics, particularly in cases of increased rotation after switches between kinesin- and dynein-mediated transport. Furthermore, unambiguous measurement of nanorod angle shows that endosome-contained nanorods align with the orientation of microtubules, suggesting a direct mechanical linkage between the ligand-receptor complex and the microtubule motors.

Rotation of endosomes demonstrates coordination of molecular motors during axonal transport

PubMed Central

Kaplan, Luke; Ierokomos, Athena; Chowdary, Praveen; Bryant, Zev; Cui, Bianxiao

2018-01-01

Long-distance axonal transport is critical to the maintenance and function of neurons. Robust transport is ensured by the coordinated activities of multiple molecular motors acting in a team. Conventional live-cell imaging techniques used in axonal transport studies detect this activity by visualizing the translational dynamics of a cargo. However, translational measurements are insensitive to torques induced by motor activities. By using gold nanorods and multichannel polarization microscopy, we simultaneously measure the rotational and translational dynamics for thousands of axonally transported endosomes. We find that the rotational dynamics of an endosome provide complementary information regarding molecular motor activities to the conventionally tracked translational dynamics. Rotational dynamics correlate with translational dynamics, particularly in cases of increased rotation after switches between kinesin- and dynein-mediated transport. Furthermore, unambiguous measurement of nanorod angle shows that endosome-contained nanorods align with the orientation of microtubules, suggesting a direct mechanical linkage between the ligand-receptor complex and the microtubule motors. PMID:29536037

Exciton transport in π-conjugated polymers with conjugation defects.

PubMed

Meng, Ruixuan; Li, Yuan; Li, Chong; Gao, Kun; Yin, Sun; Wang, Luxia

2017-09-20

In π-conjugated polymers for photovoltaic applications, intrinsic conjugation defects are known to play crucial roles in impacting exciton transport after photoexcitation. However, the understanding of the associated microscopic processes still remains limited. Here, we present a theoretical investigation of the effects of different conjugation defects on the dynamics of exciton transport in two linearly coupled poly(p-phenylene vinylene) (PPV) molecules. The model system is constructed by employing an extended version of the Su-Schrieffer-Heeger model and the exciton behaviors are simulated by means of a quantum nonadiabatic dynamics. We identify two types of conjugation defects, i.e., weakening conjugation and strengthening conjugation, which are demonstrated to play different roles in impacting the dynamics of exciton transport in the system. The weakening conjugation acts as an energy well inclined to trap a moving exciton, while the strengthening conjugation acts as an energy barrier inclined to block the exciton. We also systematically simulate both intrachain and interchain dynamics of exciton transport, and find that an exciton could experience a "short-time delaying", "trapping", "blocking", or "hopping" process, which is determined by the defect type, strength, and position. These findings provide a microscopic understanding of how the exciton transport dynamics can be impacted by conjugation defects in an actual polymer system.

Structural Studies on Cytosolic Domain of Magnesium Transporter MgtE from Enterococcus faecalis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ragumani, S.; Sauder, J; Burley, S

2009-01-01

Magnesium (Mg{sup 2+}) is an essential element for growth and maintenance of living cells. It acts as a cofactor for many enzymes and is also essential for stability of the plasma membrane. There are two distinct classes of magnesium transporters identified in bacteria that convey Mg{sup 2+} from periplasm to cytoplasm [ATPase-dependent (MgtA and MgtB) and constitutively active (CorA and MgtE)]. Previously published work on Mg{sup 2+} transporters yielded structures of full length MgtE from Thermus thermophilus, determined at 3.5 {angstrom} resolution, and its cytoplasmic domain with and without bond Mg{sup 2+} determined at 2.3 and 3.9 {angstrom} resolution, respectively.more » Here, they report the crystal structure of the Mg{sup 2+} bound form of the cytosolic portion of MgtE (residues 6-262) from Enterococcus faecalis at 2.2 {angstrom} resolution. The present structure and magnesium bound cytosolic domain structure from T. thermophilus (PDB ID: 2YVY) are structurally similar. Three magnesium binding sites are common to both MgtE full length and the present structure. Their work revealed an additional Mg{sup 2+} binding site in the E. faecalis structure. In this report, they discuss the functional significance of Mg{sup 2+} binding sites in the cytosolic domains of MgtE transporters.« less

Deschutes estuary feasibility study: hydrodynamics and sediment transport modeling

USGS Publications Warehouse

George, Douglas A.; Gelfenbaum, Guy; Lesser, Giles; Stevens, Andrew W.

2006-01-01

- Provide the completed study to the CLAMP Steering Committee so that a recommendation about a long-term aquatic environment of the basin can be made. The hydrodynamic and sediment transport modeling task developed a number of different model simulations using a process-based morphological model, Delft3D, to help address these goals. Modeling results provide a qualitative assessment of estuarine behavior both prior to dam construction and after various post-dam removal scenarios. Quantitative data from the model is used in the companion biological assessment and engineering design components of the overall study. Overall, the modeling study found that after dam removal, tidal and estuarine processes are immediately restored, with marine water from Budd Inlet carried into North and Middle Basin on each rising tide and mud flats being exposed with each falling tide. Within the first year after dam removal, tidal processes, along with the occasional river floods, act to modify the estuary bed by redistributing sediment through erosion and deposition. The morphological response of the bed is rapid during the first couple of years, then slows as a dynamic equilibrium is reached within three to five years. By ten years after dam removal, the overall hydrodynamic and morphologic behavior of the estuary is similar to the pre-dam estuary, with the exception of South Basin, which has been permanently modified by human activities. In addition to a qualitative assessment of estuarine behavior, process-based modeling provides the ability address specific questions to help to inform decision-making. Considering that predicting future conditions of a complex estuarine environment is wrought with uncertainties, quantitative results in this report are often expressed in terms of ranges of possible outcomes.

Considerations in the development of procedures for prioritizing transportation improvement projects in Virginia.

DOT National Transportation Integrated Search

2002-01-01

The transportation programming process is undergoing a fundamental change akin to that which transpired with the advent of the Intermodal Surface Transportation Efficiency Act in 1991. Some stakeholders have expressed a desire that the programming pr...

North End Runway Material Extraction and Transport Environmental Assessment

DTIC Science & Technology

2006-05-01

commercial providers, non -commercial providers, or a combination thereof Material would be transported by public road, commercial rail, ami/or barge...from commercial providers, non -commercial providers, or a combination thereof Material would be transported by public road, commercial rail, ami/or...Terminal Redevelopment NEPA National Environmental Policy Act NFA No further action NFS Non -frost susceptible NHPA National Historic Preservation

Martin Van Buren National Historic Site alternative transportation feasibility study.

DOT National Transportation Integrated Search

2012-05-31

The Martin Van Buren National Historic Site (MVBNHS) Alternative Transportation Feasibility Study examines the feasibility of : alternative transportation system (ATS) service to MVBNHS. The report investigates opportunities for a shuttle carrying vi...

Ion channel-transporter interactions

PubMed Central

Neverisky, Daniel L.; Abbott, Geoffrey W.

2016-01-01

All living cells require membrane proteins that act as conduits for the regulated transport of ions, solutes and other small molecules across the cell membrane. Ion channels provide a pore that permits often rapid, highly selective, and tightly regulated movement of ions down their electrochemical gradient. In contrast, active transporters can move moieties up their electrochemical gradient. The secondary active transporters (such as SLC superfamily solute transporters) achieve this by coupling uphill movement of the substrate to downhill movement of another ion, such as sodium. The primary active transporters (including H+/K+-ATPases and Na+/K+-ATPases) utilize ATP hydrolysis as an energy source to power uphill transport. It is well known that proteins in each of these classes work in concert with members of the other classes to ensure, for example, ion homeostasis, ion secretion, and restoration of ion balance following action potentials. More recently, evidence is emerging of direct physical interaction between true ion channels, and some primary or secondary active transporters. Here, we review the first known members of this new class of macromolecular complexes that we term “chansporters”, explore their biological roles, and discuss the pathophysiological consequences of their disruption. We compare functional and/or physical interactions between the ubiquitous KCNQ1 potassium channel and various active transporters, and examine other newly discovered chansporter complexes that suggest we may be seeing the tip of the iceberg in a newly emerging signaling modality. PMID:27098917

Americans with Disabilities Act (ADA) program review, training and support services.

DOT National Transportation Integrated Search

2010-12-01

This report describes research conducted for the New Jersey Department of Transportation (NJDOT) Division of Civil Rights to aid in its compliance efforts relative to Section 504 of the Rehabilitation Act of 1973 and Title II of the Americans with Di...

Economic benefits of employment transportation services : final report

DOT National Transportation Integrated Search

2008-06-30

This report examines the benefits that accrue from employment transportation services implemented as a result of changes in welfare policy, namely the Personal Responsibility and Work Opportunity Reconciliation Act (PRWORA) of 1996. Employment transp...

Applying Quantitative Molecular Tools for Virus Transport Studies: Opportunities and Challenges

EPA Science Inventory

Bacteriophages have been used in soil column studies for the last several decades as surrogates to study the fate and transport behavior of enteric viruses in groundwater. However, recent studies have shown that the transport behavior of bacteriophages and enteric viruses in poro...

Advance care treatment plan (ACT-Plan) for African American family caregivers: a pilot study.

PubMed

Bonner, Gloria J; Wang, Edward; Wilkie, Diana J; Ferrans, Carol E; Dancy, Barbara; Watkins, Yashika

2014-01-01

Research is limited on end-of-life treatment decisions made by African American family caregivers. In a pilot study, we examined the feasibility of implementing an advance care treatment plan (ACT-Plan), a group-based education intervention, with African American dementia caregivers. Theoretically based, the ACT-Plan included strategies to enhance knowledge, self-efficacy, and behavioral skills to make end-of-life treatment plans in advance. Cardiopulmonary resuscitation, mechanical ventilation, and tube feeding were end-of-life treatments discussed in the ACT-Plan. In a four-week pre/posttest two-group design at urban adult day care centers, 68 caregivers were assigned to the ACT-Plan or attention-control health promotion conditions. Findings strongly suggest that the ACT-Plan intervention is feasible and appropriate for African American caregivers. Self-efficacy and knowledge about dementia, cardiopulmonary resuscitation, mechanical ventilation, and tube feeding increased for ACT-Plan participants but not for the attention-control. More ACT-Plan than attention-control participants developed advance care plans for demented relatives. Findings warrant a randomized efficacy trial.

Nitrogen transporter and assimilation genes exhibit developmental stage-selective expression in maize (Zea mays L.) associated with distinct cis-acting promoter motifs.

PubMed

Liseron-Monfils, Christophe; Bi, Yong-Mei; Downs, Gregory S; Wu, Wenqing; Signorelli, Tara; Lu, Guangwen; Chen, Xi; Bondo, Eddie; Zhu, Tong; Lukens, Lewis N; Colasanti, Joseph; Rothstein, Steven J; Raizada, Manish N

2013-10-01

Nitrogen is considered the most limiting nutrient for maize (Zea mays L.), but there is limited understanding of the regulation of nitrogen-related genes during maize development. An Affymetrix 82K maize array was used to analyze the expression of ≤ 46 unique nitrogen uptake and assimilation probes in 50 maize tissues from seedling emergence to 31 d after pollination. Four nitrogen-related expression clusters were identified in roots and shoots corresponding to, or overlapping, juvenile, adult, and reproductive phases of development. Quantitative real time PCR data was consistent with the existence of these distinct expression clusters. Promoters corresponding to each cluster were screened for over-represented cis-acting elements. The 8-bp distal motif of the Arabidopsis 43-bp nitrogen response element (NRE) was over-represented in nitrogen-related maize gene promoters. This conserved motif, referred to here as NRE43-d8, was previously shown to be critical for nitrate-activated transcription of nitrate reductase (NIA1) and nitrite reductase (NIR1) by the NIN-LIKE PROTEIN 6 (NLP6) in Arabidopsis. Here, NRE43-d8 was over-represented in the promoters of maize nitrate and ammonium transporter genes, specifically those that showed peak expression during early-stage vegetative development. This result predicts an expansion of the NRE-NLP6 regulon and suggests that it may have a developmental component in maize. We also report leaf expression of putative orthologs of nitrite transporters (NiTR1), a transporter not previously reported in maize. We conclude by discussing how each of the four transcriptional modules may be responsible for the different nitrogen uptake and assimilation requirements of leaves and roots at different stages of maize development.

Statewide Transportation Improvement Program - FY 1998-2000 - Proposed Highway & Transit Improvement Program - Draft

DOT National Transportation Integrated Search

1997-10-01

The FY 1998-2000 Statewide Transportation Improvement Program (STIP) is a three-year program of highway and transit projects developed to fulfill the requirements set forth in the Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA). The ...

Stochastic study of solute transport in a nonstationary medium.

PubMed

Hu, Bill X

2006-01-01

A Lagrangian stochastic approach is applied to develop a method of moment for solute transport in a physically and chemically nonstationary medium. Stochastic governing equations for mean solute flux and solute covariance are analytically obtained in the first-order accuracy of log conductivity and/or chemical sorption variances and solved numerically using the finite-difference method. The developed method, the numerical method of moments (NMM), is used to predict radionuclide solute transport processes in the saturated zone below the Yucca Mountain project area. The mean, variance, and upper bound of the radionuclide mass flux through a control plane 5 km downstream of the footprint of the repository are calculated. According to their chemical sorption capacities, the various radionuclear chemicals are grouped as nonreactive, weakly sorbing, and strongly sorbing chemicals. The NMM method is used to study their transport processes and influence factors. To verify the method of moments, a Monte Carlo simulation is conducted for nonreactive chemical transport. Results indicate the results from the two methods are consistent, but the NMM method is computationally more efficient than the Monte Carlo method. This study adds to the ongoing debate in the literature on the effect of heterogeneity on solute transport prediction, especially on prediction uncertainty, by showing that the standard derivation of solute flux is larger than the mean solute flux even when the hydraulic conductivity within each geological layer is mild. This study provides a method that may become an efficient calculation tool for many environmental projects.

A Study on the Lack of Enforcement of Data Protection Acts

NASA Astrophysics Data System (ADS)

Burghardt, Thorben; Böhm, Klemens; Buchmann, Erik; Kühling, Jürgen; Sivridis, Anastasios

Data privacy is a fundamental human right, not only according to the EU perspective. Each EU state implements sophisticated data protection acts. Nevertheless, there are frequent media reports on data privacy violations. The scientific and the political community assume that data protection acts suffer from a lack of enforcement. This paper is an interdisciplinary study that examines this hypothesis by means of empirical facts on juridical assessment criteria - and validates it. We have inspected 100 service providers, from social online platforms to web shops. Our study considers legal requirements of the privacy policy and how providers ask for consent and react to requests for information or deletion of personal data. Our study is based on articles of German law that have a counterpart in the EU Directive 95/46/EC. Thus, our study is relevant for all EU states and all countries with similar regulations.

1997 federal highway cost allocation study : final report

DOT National Transportation Integrated Search

2009-10-01

The purpose of this case study report is to examine the ways in which metropolitan planning organizations (MPOs) and State Departments of Transportation (DOTs) have responded to Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Lega...

Monoamine Transporters as Ionotropic Receptors.

PubMed

De Felice, Louis J

2017-04-01

It is well established that glutamate and GABA signal through both ionotropic and metabotropic receptors. Conversely, it is thought that, with one exception, monoamines (dopamine, serotonin, and norepinephrine) signal via metabotropic receptors. Given their capacity to generate fast-acting currents, I suggest that the monoamine transporters should be considered as ionotropic receptors. Copyright © 2017. Published by Elsevier Ltd.

Emergency medical transport of the elderly: a population-based study.

PubMed

Wofford, J L; Moran, W P; Heuser, M D; Schwartz, E; Velez, R; Mittelmark, M B

1995-05-01

Patterns of utilization of emergency medical services transport (EMS) by the elderly are poorly understood. We determined population-based rates of EMS utilization by the elderly and characterized utilization patterns by age, gender, race, and reason for transport. This observational, population-based study was conducted in Forsyth County, NC, a semi-urban county served by one convalescent ambulance service and one EMS service. Using data on all 1990 EMS transports and the 1990 U.S. census data, age-, gender-, and race-specific transport rates for persons aged 60 or older were calculated. Reasons for transport and frequency of repeat users were established. After exclusion of transports because of an address outside the county, a nonhospital destination, a scheduled transport, or missing data, 4,688 transports (78% of total) remained for analysis. The overall rate of transport was 104/1,000 county residents. Transport rates increased for successively older five-year age groups, demonstrating a 5.7-fold stepwise increase from ages 60-65 to 85+ (51/1,000 to 291/1,000). There was no difference in mean age between patients who were frequent EMS users (more than three transports during the year) (n = 66) and other elderly transportees. Reasons for transport differed little between those 60 to 84 years of age and those 85 years of age and older with the exception of chest pain, cardiac arrest, and seizures, all of which were significantly more prevalent in the younger age group.(ABSTRACT TRUNCATED AT 250 WORDS)

78 FR 32296 - Second Allocation of Public Transportation Emergency Relief Funds in Response to Hurricane Sandy...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-29

... DEPARTMENT OF TRANSPORTATION Federal Transit Administration Second Allocation of Public... disaster that affects public transportation systems. The Disaster Relief Appropriations Act provides $10.9... projected total recovery costs for the four most severely affected public transportation systems, not...

Placental sulphate transport: a review of functional and molecular studies.

PubMed

Shennan, D B

2012-08-01

Sulphate is required by the feto-placental unit for a number of important conjugation and biosynthetic pathways. Functional studies performed several decades ago established that sulphate transport in human placental microvillus and basal membrane vesicles was mainly via a DIDS-sensitive anion-exchange mechanism. In contrast, no evidence was found for Na⁺-dependent transport. Studies performed using isolated human placental tissue confirmed anion-exchange as the main mechanism. More recently, molecular studies have established the presence of anion-exchange proteins which could play a role in transplacental sulphate movement. However, the presence of transcripts for NaS2 has been reported and has prompted the suggestion that Na⁺-sulphate cotransport may play an important role in maternal-fetal sulphate transport. This article reviews our present knowledge of placental sulphate transport, both functional and molecular, and attempts to form a model based on the available evidence. Copyright © 2012 Elsevier Ltd. All rights reserved.

Metropolitan transportation management center : a case study : Michigan intelligent transportation system : improving safety and air quality while reducing stress for motorists

DOT National Transportation Integrated Search

1999-10-01

The following case study provides a snapshot of Michigan's Intelligent Transportation Systems transportation management center (MITSC). It follows the outline provided in the companion document, Metropolitan Transportation Management Center Concepts ...

78 FR 60755 - Hazardous Materials: Enhanced Enforcement Procedures-Resumption of Transportation

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-02

.... Summary of MAP-21 and Final Rule V. Summary Review of Amendments VI. Regulatory Analyses and Notices A.... Executive Summary On July 6, 2012, the President signed the Moving Ahead for Progress in the 21st Century Act, or the MAP-21, which included the Hazardous Materials Transportation Safety Improvement Act of...

A Study of Transport Airplane Crash-Resistant Fuel Systems

NASA Technical Reports Server (NTRS)

Jones, Lisa (Technical Monitor); Robertson, S. H.; Johnson, N. B.; Hall, D. S.; Rimson, I. J.

2002-01-01

This report presents the results of a study, funded by the Federal Aviation Administration (FAA), of transport airplane crash-resistant fuel system (CRFS). The report covers the historical studies related to aircraft crash fires and fuel containment concepts undertaken by the FAA, NASA, and the U.S. Army, which ultimately led to the current state of the art in CRFS technology. It describes the basic research, testing, field investigations and production efforts which have led to the highly successful military CRFS, which has saved many lives and reduced costs of accidents. Current CRFS technology used in transport category airplanes is defined and compared to the available state-of-the-art technology. The report provides information to the FAA and other government organizations which can help them plan their efforts to improve the state of crash fire protection in the transport airplane fleet. The report provides guidance to designers looking for information about CRFS design problems, analysis tools to use for product improvement, and a summary of current and proposed regulations for transport category airplane fuel systems.

Electrical and Thermal Transport Property Studies of High-Temperature Thermoelectric Materials.

DTIC Science & Technology

1984-12-15

Transport Property Studies of High-Temperature Thermoelectric Mateial 12. PERSONAL AUTHIOR(S) 113. TYPE OF REPORT 13b. TIME COVERED Ai DATE OF REPORtT (Yr...with an ABO(3 perovskite structure. Transport properties have been determined for various doping ele- ments and for different compositions. These data...THERMAL TRANSPORT PROPERTY STUDIES Unannounced [j OF HIGH-TEMPERATURE THERMOELECTRIC MATERIALS Justi±icI iou. CONTRACT F-49620-83-0109 DEF By-- Battelle

Chicago Area Transportation Study (CATS): Methodological Overview

DOT National Transportation Integrated Search

1994-04-01

This report contains a methodological discussion of the Chicago Area : Transportation Study (CATS) 1990 Household Travel Survey. It was prepared to : assist those who are working with the Household Travel Survey database. This : report concentrates o...

78 FR 76152 - Agency Information Collection Activities: Transportation Entry and Manifest of Goods Subject to...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-16

... Activities: Transportation Entry and Manifest of Goods Subject to CBP Inspection and Permit AGENCY: U.S... the Paperwork Reduction Act: Transportation Entry and Manifest of Goods Subject to CBP Inspection and..., mechanical, or other technological techniques or other forms of information. Title: Transportation Entry and...

49 CFR 1.25 - Delegations to the Under Secretary of Transportation for Policy.

Code of Federal Regulations, 2012 CFR

2012-10-01

... international airport facilities. (6) Section 11 of the Clayton Act, Public Law 63-212 [15 U.S.C. 21], relating... section 101(a)(2) of the Air Transportation Safety and System Stabilization Act, Public Law 107-42 [49 U.S... implementation of the National Environmental Policy Act of 1969, Public Law 91-190, as amended (42 U.S.C. 4321...

49 CFR 1.25 - Delegations to the Under Secretary of Transportation for Policy.

Code of Federal Regulations, 2013 CFR

2013-10-01

... international airport facilities. (6) Section 11 of the Clayton Act, Public Law 63-212 [15 U.S.C. 21], relating... section 101(a)(2) of the Air Transportation Safety and System Stabilization Act, Public Law 107-42 [49 U.S... implementation of the National Environmental Policy Act of 1969, Public Law 91-190, as amended (42 U.S.C. 4321...

49 CFR 1.25 - Delegations to the Under Secretary of Transportation for Policy.

Code of Federal Regulations, 2014 CFR

2014-10-01

... international airport facilities. (6) Section 11 of the Clayton Act, Public Law 63-212 [15 U.S.C. 21], relating... section 101(a)(2) of the Air Transportation Safety and System Stabilization Act, Public Law 107-42 [49 U.S... implementation of the National Environmental Policy Act of 1969, Public Law 91-190, as amended (42 U.S.C. 4321...

1977 Nationwide Personal Transportation Study : household travel

DOT National Transportation Integrated Search

1982-07-01

This report is one of a series prepared from the findings of the 1977 Nationwide Personal Transportation Study (NPTS). The report examines the relationship between household travel patterns and characteristics of the household. Vehicle trips and vehi...

Aluminum-Activated Malate Transporters Can Facilitate GABA Transport.

PubMed

Ramesh, Sunita A; Kamran, Muhammad; Sullivan, Wendy; Chirkova, Larissa; Okamoto, Mamoru; Degryse, Fien; McLaughlin, Michael; Gilliham, Matthew; Tyerman, Stephen D

2018-05-01

Plant aluminum-activated malate transporters (ALMTs) are currently classified as anion channels; they are also known to be regulated by diverse signals, leading to a range of physiological responses. Gamma-aminobutyric acid (GABA) regulation of anion flux through ALMT proteins requires a specific amino acid motif in ALMTs that shares similarity with a GABA binding site in mammalian GABA A receptors. Here, we explore why TaALMT1 activation leads to a negative correlation between malate efflux and endogenous GABA concentrations ([GABA] i ) in both wheat ( Triticum aestivum ) root tips and in heterologous expression systems. We show that TaALMT1 activation reduces [GABA] i because TaALMT1 facilitates GABA efflux but GABA does not complex Al 3+ TaALMT1 also leads to GABA transport into cells, demonstrated by a yeast complementation assay and via 14 C-GABA uptake into TaALMT1 -expressing Xenopus laevis oocytes; this was found to be a general feature of all ALMTs we examined. Mutation of the GABA motif (TaALMT1 F213C ) prevented both GABA influx and efflux, and resulted in no correlation between malate efflux and [GABA] i We conclude that ALMTs are likely to act as both GABA and anion transporters in planta. GABA and malate appear to interact with ALMTs in a complex manner to regulate each other's transport, suggestive of a role for ALMTs in communicating metabolic status. © 2018 American Society of Plant Biologists. All rights reserved.

19 CFR 4.74 - Transportation orders.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 1 2010-04-01 2010-04-01 false Transportation orders. 4.74 Section 4.74 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY... issued under authority of the Defense Production Act of 1950 (50 U.S.C. App. 2061-2066). ...

19 CFR 4.74 - Transportation orders.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 19 Customs Duties 1 2011-04-01 2011-04-01 false Transportation orders. 4.74 Section 4.74 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY... issued under authority of the Defense Production Act of 1950 (50 U.S.C. App. 2061-2066). ...

19 CFR 4.74 - Transportation orders.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 19 Customs Duties 1 2012-04-01 2012-04-01 false Transportation orders. 4.74 Section 4.74 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY... issued under authority of the Defense Production Act of 1950 (50 U.S.C. App. 2061-2066). ...

19 CFR 4.74 - Transportation orders.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 1 2013-04-01 2013-04-01 false Transportation orders. 4.74 Section 4.74 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY... issued under authority of the Defense Production Act of 1950 (50 U.S.C. App. 2061-2066). ...

Functional studies of Drosophila zinc transporters reveal the mechanism for dietary zinc absorption and regulation

PubMed Central

2013-01-01

Background Zinc is key to the function of many proteins, but the process of dietary zinc absorption is not well clarified. Current knowledge about dietary zinc absorption is fragmented, and mostly derives from incomplete mammalian studies. To gain a comprehensive picture of this process, we systematically characterized all zinc transporters (that is, the Zip and ZnT family members) for their possible roles in dietary zinc absorption in a genetically amenable model organism, Drosophila melanogaster. Results A set of plasma membrane-resident zinc transporters was identified to be responsible for absorbing zinc from the lumen into the enterocyte and the subsequent exit of zinc to the circulation. dZip1 and dZip2, two functionally overlapping zinc importers, are responsible for absorbing zinc from the lumen into the enterocyte. Exit of zinc to the circulation is mediated through another two functionally overlapping zinc exporters, dZnT1, and its homolog CG5130 (dZnT77C). Somewhat surprisingly, it appears that the array of intracellular ZnT proteins, including the Golgi-resident dZnT7, is not directly involved in dietary zinc absorption. By modulating zinc status in different parts of the body, we found that regulation of dietary zinc absorption, in contrast to that of iron, is unresponsive to bodily needs or zinc status outside the gut. The zinc transporters that are involved in dietary zinc absorption, including the importers dZip1 and dZip2, and the exporter dZnT1, are respectively regulated at the RNA and protein levels by zinc in the enterocyte. Conclusions Our study using the model organism Drosophila thus starts to reveal a comprehensive sketch of dietary zinc absorption and its regulatory control, a process that is still incompletely understood in mammalian organisms. The knowledge gained will act as a reference for future mammalian studies, and also enable an appreciation of this important process from an evolutionary perspective. PMID:24063361

Project UCARE : Uniform Commuter Assistance Reporting and Evaluation for transportation demand management programs, [summary].

DOT National Transportation Integrated Search

2013-09-01

The federal transportation reauthorization called : Moving Ahead for Progress in the 21st Century Act : (MAP-21) creates a program that addresses many : challenges facing the U.S. transportation system. : These challenges include improving safety, : ...

Predictive study of charge transport in disordered semiconducting polymers.

PubMed

Athanasopoulos, Stavros; Kirkpatrick, James; Martínez, Diego; Frost, Jarvist M; Foden, Clare M; Walker, Alison B; Nelson, Jenny

2007-06-01

We present a theoretical study of charge transport in disordered semiconducting polymers that relates the charge mobility to the chemical structure and the physical morphology in a novel multiscale approach. Our studies, focusing on poly(9,9-dioctylfluorene) (PFO), show that the charge mobility is dominated by pathways with the highest interchain charge-transfer rates. We also find that disorder is not always detrimental to charge transport. We find good agreement with experimental time-of-flight mobility data in highly aligned PFO films.

A Course of Study in Acting Fundamentals for Junior College.

ERIC Educational Resources Information Center

Greening, Ruth Patricia Browne

A complete and comprehensive course of study in acting fundamentals for the junior college is presented. Its overall goals are to develop individual sensitivity and creativity, without neglecting essential skills and traditional theatrical and academic values. Justification of major course objectives in the junior college curriculum, presentation…

Space Transportation Booster Engine (STBE) configuration study

NASA Technical Reports Server (NTRS)

1986-01-01

The overall objective of this Space Transportation Booster Engine (STBE) study is to identify candidate engine configurations which enhance vehicle performance and provide operational flexibility at low cost. The specific objectives are as follows: (1) to identify and evaluate candidate LOX/HC engine configurations for the Advanced Space Transportation System for an early 1995 IOC and a late 2000 IOC; (2) to select one optimum engine for each time period; 3) to prepare a conceptual design for each configuration; (4) to develop a technology plan for the 2000 IOC engine; and, (5) to prepare preliminary programmatic planning and analysis for the 1995 IOC engine.

75 FR 60772 - Agency Information Collection Activities: Transportation Entry and Manifest of Goods Subject to...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-01

... Activities: Transportation Entry and Manifest of Goods Subject to CBP Inspection and Permit AGENCY: U.S... the Paperwork Reduction Act: Transportation Entry and Manifest of Goods Subject to CBP Inspection and... techniques or other forms of information. Title: Transportation Entry and Manifest of Goods Subject to CBP...

Focusing Resources, Economic Investment, and Guidance to Help Transportation Act of 2011

THOMAS, 112th Congress

Sen. Lautenberg, Frank R. [D-NJ

2011-02-16

Senate - 02/16/2011 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Focusing Resources, Economic Investment, and Guidance to Help Transportation Act of 2010

THOMAS, 111th Congress

Sen. Lautenberg, Frank R. [D-NJ

2010-07-22

Senate - 07/22/2010 Read twice and referred to the Committee on Commerce, Science, and Transportation. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Neurotrophin Signaling via Long-Distance Axonal Transport

NASA Astrophysics Data System (ADS)

Chowdary, Praveen D.; Che, Dung L.; Cui, Bianxiao

2012-05-01

Neurotrophins are a family of target-derived growth factors that support survival, development, and maintenance of innervating neurons. Owing to the unique architecture of neurons, neurotrophins that act locally on the axonal terminals must convey their signals across the entire axon for subsequent regulation of gene transcription in the cell nucleus. This long-distance retrograde signaling, a motor-driven process that can take hours or days, has been a subject of intense interest. In the last decade, live-cell imaging with high sensitivity has significantly increased our capability to track the transport of neurotrophins, their receptors, and subsequent signals in real time. This review summarizes recent research progress in understanding neurotrophin-receptor interactions at the axonal terminal and their transport dynamics along the axon. We emphasize high-resolution studies at the single-molecule level and also discuss recent technical advances in the field.

Governors Island alternative transportation study : support to general management plan

DOT National Transportation Integrated Search

2004-12-01

This report, funded by the NPS Alternative Transportation Program (ATP), was commissioned in conjunction with the GMP. As a high-level transportation study, it was intended to inform the GMP planning process and to aid in the conception and developme...

Spin-polarized transport in multiterminal silicene nanodevices

NASA Astrophysics Data System (ADS)

Xu, Ning

2018-01-01

The spin-polarized transport properties of multiterminal silicene nanodevices are studied using the tight binding model and Landauer-Buttier approach. We propose a four-terminal †-shaped junction device and two types of three-terminal T-shaped junction devices, which are made of the crossing of a zigzag and an armchair silicene nanoribbon. If the electrons are injected into the metallic lead, the near-perfect spin polarization with 100% around the Fermi energy can be achieved easily at the other semiconducting leads. Thus the multiterminal silicene nanodevices can act as controllable spin filters.

Norepinephrine Transporter in Major Depressive Disorder: A PET Study.

PubMed

Moriguchi, Sho; Yamada, Makiko; Takano, Harumasa; Nagashima, Tomohisa; Takahata, Keisuke; Yokokawa, Keita; Ito, Takehito; Ishii, Tatsuya; Kimura, Yasuyuki; Zhang, Ming-Rong; Mimura, Masaru; Suhara, Tetsuya

2017-01-01

The norepinephrine transporter has been suggested to play a crucial role in major depressive disorder. However, norepinephrine transporter availability in major depressive disorder and its role with clinical symptoms are not known. The authors tested norepinephrine transporter availability in patients with major depressive disorder with the aim to identify any associations between test results and clinical symptoms. The present research was a cross-sectional study in which 19 patients with major depressive disorder and 19 age- and sex-matched healthy comparison subjects underwent positron emission tomography scanning to evaluate the norepinephrine transporter availability measured by the radioligand (S,S)-[ 18 F]FMeNER-D 2 . Norepinephrine transporter availability in the thalamus and its subregions was quantified in terms of nondisplaceable binding potential (BP ND ). The authors also analyzed the association between norepinephrine transporter availability and clinical symptoms. Compared with healthy subjects, patients with major depressive disorder showed 29.0% higher BP ND values in the thalamus and, in particular, 28.2% higher values in the thalamic subregion anatomically connected to the prefrontal cortex. Elevated norepinephrine transporter availability in the thalamus in patients was positively correlated with attention, as measured by the Trail Making Test, part A. These findings revealed altered norepinephrine transmission in patients with major depressive disorder, suggesting that this alteration could be related to attention in this patient population.

Hexose transport by brain slices: further studies on energy dependence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kyle-Lillegard, J.; Gold, B.I.

1983-04-01

We studied the uptake of (/sup 3/H)2-deoxyglucose ((/sup 3/H)2DG) by slices of rat cerebral cortex in vitro as a model of glucose transport by brain. Slices were incubated with (/sup 3/H)2DG, or with L-(/sup 3/H)glucose as a marker for diffusion; the difference between (/sup 3/H)2DG uptake and L-(/sup 3/H)glucose uptake was defined as net (/sup 3/H)2DG transport. Net (/sup 3/H)2DG transport was a function of incubation temperature, with an estimated temperature coefficient of 1.87 from 15 degrees C to 25 degrees C. The net uptake of (/sup 3/H)2DG was not inhibited by phlorizin or phloretin in concentrations well above themore » reported Ki of these inhibitors for hexose uptake in other systems. To examine the hypothesis that (/sup 3/H)2DG transport by brain slices is dependent on mitochondrial energy, we studied net (/sup 3/H)2DG uptake by slices which had been preincubated in media designed to alter intracellular ATP stores. The transport process was very sensitive to inhibition by DNP, but the correlation between (/sup 3/H)2DG transport and ATP levels was unclear. In contrast to our published hypothesis that the transport process required mitochondrial energy, these data indicate that dependence on energy is not absolute.« less

United States Department of Transportation report to Congress on public-private partnerships, December 2004.

DOT National Transportation Integrated Search

2004-12-01

House Report 108-243 (2003) accompanying the FY 2004 Department of Transportation : Appropriations Act requested the U.S. Department of Transportation (DOT) to prepare a : report identifying the impediments to the formation of large, capital-intensiv...

1977 Nationwide Personal Transportation Study : vehicle occupancy

DOT National Transportation Integrated Search

1981-04-01

This report is part of a series that presents findings from the 1977 Nationwide Personal Transportation Study (NPTS). This report contains average vehicle occupancy rates by trip characteristics (trip purpose, trip length, time of day and day of the ...

Wave-induced bedload transport - a study of the southern Baltic coastal zone

NASA Astrophysics Data System (ADS)

Dudkowska, Aleksandra; Gic-Grusza, Gabriela

2017-03-01

The wave-induced bedload transport and spatial distribution of its magnitude in the southern Baltic coastal zone of Poland are estimated. The vicinity of Lubiatowo was selected as a representative part of the Polish coast. It was assumed that transport is a function of shear stress; alternative approaches, based on force balances and discharge relationships, were not considered in the present study. Four models were studied and compared over a wide range of bottom shear stress and wind-wave conditions. The set of models comprises classic theories that assume a simplified influence of turbulence on sediment transport (e.g., advocated by authors such as Du Boys, Meyer-Peter and Müller, Ribberink, Engelund and Hansen). It is shown that these models allow to estimate transport comparable to measured values under similar environmental conditions. A united general model for bedload transport is proposed, and a set of maps of wave bedload transport for various wind conditions in the study area is presented.

Surface transportation : clear federal role and criteria-based selection process could improve three national and regional infrastructure programs.

DOT National Transportation Integrated Search

2009-02-01

To help meet increasing transportation demands, the Safe, Accountable, Flexible, Efficient Transportation Equity Act: A Legacy for Users (SAFETEA-LU) created three programs to invest federal funds in national and regional transportation infrastructur...

Molecular Dynamics Investigation of Cl− and Water Transport through a Eukaryotic CLC Transporter

PubMed Central

Cheng, Mary Hongying; Coalson, Rob D.

2012-01-01

Early crystal structures of prokaryotic CLC proteins identified three Cl– binding sites: internal (Sint), central (Scen), and external (Sext). A conserved external GLU (GLUex) residue acts as a gate competing for Sext. Recently, the first crystal structure of a eukaryotic transporter, CmCLC, revealed that in this transporter GLUex competes instead for Scen. Here, we use molecular dynamics simulations to investigate Cl– transport through CmCLC. The gating and Cl–/H+ transport cycle are inferred through comparative molecular dynamics simulations with protonated and deprotonated GLUex in the presence/absence of external potentials. Adaptive biasing force calculations are employed to estimate the potential of mean force profiles associated with transport of a Cl– ion from Sext to Sint, depending on the Cl– occupancy of other sites. Our simulations demonstrate that protonation of GLUex is essential for Cl– transport from Sext to Scen. The Scen site may be occupied by two Cl– ions simultaneously due to a high energy barrier (∼8 Kcal/mol) for a single Cl– ion to translocate from Scen to Sint. Binding two Cl– ions to Scen induces a continuous water wire from Scen to the extracellular solution through the side chain of the GLUex gate. This may initiate deprotonation of GLUex, which then drives the two Cl– ions out of Scen toward the intracellular side via two putative Cl– transport paths. Finally, a conformational cycle is proposed that would account for the exchange stoichiometry. PMID:22455919

The Washington, DC, Youth Curfew: effect on transports of injured youth and homicides.

PubMed

Moscovitz, H; Milzman, D; Haywood, Y

2000-01-01

Curfews are implemented to curtail youth violence. Trauma systems and emergency medical services (EMS) may need to prepare for changes in patient volume resulting from local ordinances. This study evaluated the impact of the 1995 Washington, DC, Juvenile Curfew Act on EMS transports of injured youth and on youth homicides. A retrospective, comparative cohort study was performed. Transports of injured youth and youth homicides were counted in corresponding months of 1994 and 1995. Cohorts were formed by year, time of day, age group, and mechanism of injury. Year-to-year statistical comparisons of injury proportions were performed using the chi square and Fisher's exact tests. One thousand forty-eight transports were included. No significant difference was observed in transports with curfew implementation. Most assaults on youth occurred outside the curfew time. No effect of the curfew on homicides was detected. Of 67 homicides, only two victims were under the curfew. No effect of the curfew on transports for injuries or on homicides was demonstrated. The curfew was not in effect during the period of highest risk.

ZIFL1.1 transporter modulates polar auxin transport by stabilizing membrane abundance of multiple PINs in Arabidopsis root tip

PubMed Central

Remy, Estelle; Baster, Pawel; Friml, Jiří; Duque, Paula

2013-01-01

Cell-to-cell directional flow of the phytohormone auxin is primarily established by polar localization of the PIN auxin transporters, a process tightly regulated at multiple levels by auxin itself. We recently reported that, in the context of strong auxin flows, activity of the vacuolar ZIFL1.1 transporter is required for fine-tuning of polar auxin transport rates in the Arabidopsis root. In particular, ZIFL1.1 function protects plasma-membrane stability of the PIN2 carrier in epidermal root tip cells under conditions normally triggering PIN2 degradation. Here, we show that ZIFL1.1 activity at the root tip also promotes PIN1 plasma-membrane abundance in central cylinder cells, thus supporting the notion that ZIFL1.1 acts as a general positive modulator of polar auxin transport in roots. PMID:23857365

Integration, status and potential of environmental justice and the social impact assessment process in transportation development in Missouri

DOT National Transportation Integrated Search

2004-07-01

This research examines the Social Impact Assessment Process at the Missouri Department of Transportation as directed by the National Environmental Policy Act (NEPA). Four case studies are used to assess the influence of human-dimension impacts in tra...

Predicting the use of public transportation: a case study from Putrajaya, Malaysia.

PubMed

Borhan, Muhamad Nazri; Syamsunur, Deprizon; Akhir, Norliza Mohd; Yazid, Muhamad Razuhanafi Mat; Ismail, Amiruddin; Rahmat, Riza Atiq

2014-01-01

Putrajaya is a new federal administrative capital of Malaysia which has been set to achieve a 70% share of all travels by public transport in the city area. However, the current modal split between the public transport and private transport is 15:85. In order to understand travelers' willingness to use the public transport, a conceptual model has been developed to determine the factors that affect them to use the public transport instead of travelling in their own cars. Various variables such as service quality, environmental impact, attitude, and behavior intention were analyzed and tested using structural equation model (SEM). Results indicate that the service quality and attitude are found to have positive effects on the behavioral intention of taking the public transport. Other than this, this study also shows that the service quality and environmental impact have some positive influences on the attitude to using the public transport. However, environmental impact has no significant, positive, and direct effect on behavioral intention. The results of this study demonstrate that the model that was developed is useful in predicting the public transport and it could provide a more complete understanding of behavioral intention towards public transport use.

Welfare maximisation in public transport : an analysis of the development in 7 Norwegian cities : summary

DOT National Transportation Integrated Search

2001-01-01

Framework conditions for Norwegian public transport have changed substantially over : the past two decades. Operating subsidies in Norwegian conurbations have been cut : dramatically. Changes in the Transport Act, which allowed for competitive tender...

Tire pressure special study : data documentation

DOT National Transportation Integrated Search

2002-01-01

In 2000, Congress passed the Transportation Recall Enhancement, Accountability, and : Documentation (TREAD) Act. Section 12 of this act directed the Department of Transportation : to complete a rulemaking requiring implementation of a warning system ...

Intelligent Transportation Systems Early Deployment Planning Study

DOT National Transportation Integrated Search

1996-06-01

INTELLIGENT TRANSPORTATION SYSTEMS (ITS) REFER TO INNOVATIVE APPROACHES TO SOLVING TRANSPORTATION PROBLEMS AND PROVIDING SERVICES TO TRAVELERS. ITS SOLUTIONS ARE TYPICALLY BASED ON A USER'S VIEW OF THE TRANSPORTATION SYSTEM, AND RELY ON PARTNERSHIPS ...

Binational border transportation infrastructure : needs assessment study.

DOT National Transportation Integrated Search

2004-07-01

In 1994, the U.S. Department of Transportation (DOT) and Mexicos Secretariat of Communications and : Transportation (Secretara de Comunicaciones y Transportes (SCT)) signed a Memorandum of Understanding : (MOU) outlining the creation of the Join...

Cargo transportation by airships: A systems study

NASA Technical Reports Server (NTRS)

Huang, C. J.; Dalton, C.

1976-01-01

A systems engineering study of a lighter than air airship transportation system was conducted. The feasibility of the use of airships in hauling cargo was demonstrated. Social, legal, environmental and political factors were considered as well as the technical factors necessary to design an effective airship transportation system. In order to accomplish an effective airship transportation program two phases of implementation were recommended. Phase I would involve a fleet of rigid airships of 3.5 million cubic feet displacement capable of carrying 25 tons of cargo internal to the helium-filled gas bag. The Phase I fleet would demonstrate the economic and technical feasibility of modern-day airships while providing a training capability for the construction and operation of larger airships. The Phase II portion would be a fleet of rigid airships of 12 million cubic feet displacement capable of carrying a cargo of 100 tons a distance of 2,000 miles at a cruising speed of 60 mph. An economic analysis is given for a variety of missions for both Phase I and Phase II airships.

Organelle-localized potassium transport systems in plants.

PubMed

Hamamoto, Shin; Uozumi, Nobuyuki

2014-05-15

Some intracellular organelles found in eukaryotes such as plants have arisen through the endocytotic engulfment of prokaryotic cells. This accounts for the presence of plant membrane intrinsic proteins that have homologs in prokaryotic cells. Other organelles, such as those of the endomembrane system, are thought to have evolved through infolding of the plasma membrane. Acquisition of intracellular components (organelles) in the cells supplied additional functions for survival in various natural environments. The organelles are surrounded by biological membranes, which contain membrane-embedded K(+) transport systems allowing K(+) to move across the membrane. K(+) transport systems in plant organelles act coordinately with the plasma membrane intrinsic K(+) transport systems to maintain cytosolic K(+) concentrations. Since it is sometimes difficult to perform direct studies of organellar membrane proteins in plant cells, heterologous expression in yeast and Escherichia coli has been used to elucidate the function of plant vacuole K(+) channels and other membrane transporters. The vacuole is the largest organelle in plant cells; it has an important task in the K(+) homeostasis of the cytoplasm. The initial electrophysiological measurements of K(+) transport have categorized three classes of plant vacuolar cation channels, and since then molecular cloning approaches have led to the isolation of genes for a number of K(+) transport systems. Plants contain chloroplasts, derived from photoautotrophic cyanobacteria. A novel K(+) transport system has been isolated from cyanobacteria, which may add to our understanding of K(+) flux across the thylakoid membrane and the inner membrane of the chloroplast. This chapter will provide an overview of recent findings regarding plant organellar K(+) transport proteins. Copyright © 2014 Elsevier GmbH. All rights reserved.

Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters

PubMed Central

Pajor, Ana M.

2006-01-01

The SLC13 gene family consists of five members in humans, with corresponding orthologs from different vertebrate species. All five genes code for sodium-coupled transporters that are found on the plasma membrane. Two of the transporters, NaS1 and NaS2, carry substrates such as sulfate, selenate and thiosulfate. The other members of the family (NaDC1, NaDC3, and NaCT) are transporters for di- and tri-carboxylates including succinate, citrate and α-ketoglutarate. The SLC13 transporters from vertebrates are electrogenic and they produce inward currents in the presence of sodium and substrate. Substrate-independent leak currents have also been described. Structure–function studies have identified the carboxy terminal half of these proteins as the most important for determining function. Transmembrane helices 9 and 10 may form part of the substrate permeation pathway and participate in conformational changes during the transport cycle. This review also discusses new members of the SLC13 superfamily that exhibit both sodium-dependent and sodium-independent transport mechanisms. The Indy protein from Drosophila, involved in determining lifespan, and the plant vacuolar malate transporter are both sodium-independent dicarboxylate transporters, possibly acting as exchangers. The purpose of this review is to provide an update on new advances in this gene family, particularly on structure–function studies and new members of the family. PMID:16211368

Strategic plan for deployment of intelligent transportation systems in the Interstate 71 corridor (Columbus to Cleveland) : final report

DOT National Transportation Integrated Search

1998-04-01

The Intermodal Surface Transportation Efficiency Act (ISTEA} signed by the U.S. Congress in December of 199 1 called for improvements in surface transportation through technological advancements. The U.S. Department of Transportation subsequently lau...

Built Environment and Active Transport to School (BEATS) Study: protocol for a cross-sectional study

PubMed Central

Mandic, Sandra; Williams, John; Moore, Antoni; Hopkins, Debbie; Flaherty, Charlotte; Wilson, Gordon; García Bengoechea, Enrique; Spence, John C

2016-01-01

Introduction Active transport to school (ATS) is a convenient way to increase physical activity and undertake an environmentally sustainable travel practice. The Built Environment and Active Transport to School (BEATS) Study examines ATS in adolescents in Dunedin, New Zealand, using ecological models for active transport that account for individual, social, environmental and policy factors. The study objectives are to: (1) understand the reasons behind adolescents and their parents' choice of transport mode to school; (2) examine the interaction between the transport choices, built environment, physical activity and weight status in adolescents; and (3) identify policies that promote or hinder ATS in adolescents. Methods and analysis The study will use a mixed-method approach incorporating both quantitative (surveys, anthropometry, accelerometers, Geographic Information System (GIS) analysis, mapping) and qualitative methods (focus groups, interviews) to gather data from students, parents, teachers and school principals. The core data will include accelerometer-measured physical activity, anthropometry, GIS measures of the built environment and the use of maps indicating route to school (students)/work (parents) and perceived safe/unsafe areas along the route. To provide comprehensive data for understanding how to change the infrastructure to support ATS, the study will also examine complementary variables such as individual, family and social factors, including student and parental perceptions of walking and cycling to school, parental perceptions of different modes of transport to school, perceptions of the neighbourhood environment, route to school (students)/work (parents), perceptions of driving, use of information communication technology, reasons for choosing a particular school and student and parental physical activity habits, screen time and weight status. The study has achieved a 100% school recruitment rate (12 secondary schools). Ethics and

Information needs to support state and local transportation decision making into the 21st century

DOT National Transportation Integrated Search

1997-03-01

The Intermodal Surface Transportation Efficiency Act of 1991 (ISTEA) established new requirements for data development and dissemination that have had an impact on federal, state, and local transportation planning processes across the United States. ...

A Study of the Relationship between the ACT College Mathematics Readiness Standard and College Mathematics Achievement

ERIC Educational Resources Information Center

Harwell, Michael; Moreno, Mario; Post, Thomas

2016-01-01

This study examined the relationship between the American College Testing (ACT) college mathematics readiness standard and college mathematics achievement using a sample of students who met or exceeded the minimum 3 years high school mathematics coursework recommended by ACT. According to ACT, a student who scores 22 or higher on the ACT…

78 FR 62362 - Revisions to Procedural Regulations Governing Transportation by Intrastate Pipelines; Electronic...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-21

...] Revisions to Procedural Regulations Governing Transportation by Intrastate Pipelines; Electronic Tariff... under the Commission's jurisdiction pursuant to the Natural Gas Policy Act of 1978 or the Natural Gas Act.\\1\\ Take notice that, effective November 12, 2013, the list of available eTariff Type of Filing...

49 CFR 1.25a - Redelegations by the Under Secretary of Transportation for Policy.

Code of Federal Regulations, 2012 CFR

2012-10-01

... facilities. (vi) Section 11 of the Clayton Act, Public Law 63-212 [15 U.S.C. 21], relating to air carriers... section 101(a)(2) of the Air Transportation Safety and System Stabilization Act, Public Law 107-42 [49 U.S... National Environmental Policy Act of 1969, Public Law 91-190, as amended (42 U.S.C. 4321-4347) within the...

49 CFR 1.25a - Redelegations by the Under Secretary of Transportation for Policy.

Code of Federal Regulations, 2014 CFR

2014-10-01

... facilities. (vi) Section 11 of the Clayton Act, Public Law 63-212 [15 U.S.C. 21], relating to air carriers... section 101(a)(2) of the Air Transportation Safety and System Stabilization Act, Public Law 107-42 [49 U.S... National Environmental Policy Act of 1969, Public Law 91-190, as amended (42 U.S.C. 4321-4347) within the...

49 CFR 1.25a - Redelegations by the Under Secretary of Transportation for Policy.

Code of Federal Regulations, 2013 CFR

2013-10-01

... facilities. (vi) Section 11 of the Clayton Act, Public Law 63-212 [15 U.S.C. 21], relating to air carriers... section 101(a)(2) of the Air Transportation Safety and System Stabilization Act, Public Law 107-42 [49 U.S... National Environmental Policy Act of 1969, Public Law 91-190, as amended (42 U.S.C. 4321-4347) within the...

Integrated Application of Active Controls (IAAC) Technology to an Advanced Subsonic Transport: Project Plan

NASA Technical Reports Server (NTRS)

1981-01-01

The state of the art of active controls technology (ACT) and a recommended ACT development program plan are reviewed. The performance benefits and cost of ownership of an integrated application of ACT to civil transport aircraft is to be assessed along with the risk and laboratory and/or flight experiments designed to reduce the technical risks to a commercially acceptable level.

Summary of the Department of Transportation Rail-Highway Crossing Accident Prediction Formulas and Resource Model

DOT National Transportation Integrated Search

1982-09-01

The Highway Safety Acts of 1973 and 1976, and the Surface Transportation Assistance Act of 1978, provide funding authorizations to individual states to improve safety at public rail-highway crossings. The installation of active motorist warning devic...

Transportation conformity particulate matter hot-spot air quality modeling.

DOT National Transportation Integrated Search

2013-07-01

In light of the new development in particulate matter (PM) hot-spot regulations and Illinois Department : of Transportation (IDOT)s National Environmental Policy Act (NEPA) documentation requirements, : this project is intended to (1) perform and ...

Parametric study of transport beam lines for electron beams accelerated by laser-plasma interaction

NASA Astrophysics Data System (ADS)

Scisciò, M.; Lancia, L.; Migliorati, M.; Mostacci, A.; Palumbo, L.; Papaphilippou, Y.; Antici, P.

2016-03-01

In the last decade, laser-plasma acceleration of high-energy electrons has attracted strong attention in different fields. Electrons with maximum energies in the GeV range can be laser-accelerated within a few cm using multi-hundreds terawatt (TW) lasers, yielding to very high beam currents at the source (electron bunches with up to tens-hundreds of pC in a few fs). While initially the challenge was to increase the maximum achievable electron energy, today strong effort is put in the control and usability of these laser-generated beams that still lack of some features in order to be used for applications where currently conventional, radio-frequency (RF) based, electron beam lines represent the most common and efficient solution. Several improvements have been suggested for this purpose, some of them acting directly on the plasma source, some using beam shaping tools located downstream. Concerning the latter, several studies have suggested the use of conventional accelerator magnetic devices (such as quadrupoles and solenoids) as an easy implementable solution when the laser-plasma accelerated beam requires optimization. In this paper, we report on a parametric study related to the transport of electron beams accelerated by laser-plasma interaction, using conventional accelerator elements and tools. We focus on both, high energy electron beams in the GeV range, as produced on petawatt (PW) class laser systems, and on lower energy electron beams in the hundreds of MeV range, as nowadays routinely obtained on commercially available multi-hundred TW laser systems. For both scenarios, our study allows understanding what are the crucial parameters that enable laser-plasma accelerators to compete with conventional ones and allow for a beam transport. We show that suitable working points require a tradeoff-combination between low beam divergence and narrow energy spread.

Parametric study of transport beam lines for electron beams accelerated by laser-plasma interaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scisciò, M.; Antici, P., E-mail: patrizio.antici@polytechnique.edu; INRS-EMT, Université du Québec, 1650 Lionel Boulet, Varennes, Québec J3X 1S2

2016-03-07

In the last decade, laser-plasma acceleration of high-energy electrons has attracted strong attention in different fields. Electrons with maximum energies in the GeV range can be laser-accelerated within a few cm using multi-hundreds terawatt (TW) lasers, yielding to very high beam currents at the source (electron bunches with up to tens-hundreds of pC in a few fs). While initially the challenge was to increase the maximum achievable electron energy, today strong effort is put in the control and usability of these laser-generated beams that still lack of some features in order to be used for applications where currently conventional, radio-frequencymore » (RF) based, electron beam lines represent the most common and efficient solution. Several improvements have been suggested for this purpose, some of them acting directly on the plasma source, some using beam shaping tools located downstream. Concerning the latter, several studies have suggested the use of conventional accelerator magnetic devices (such as quadrupoles and solenoids) as an easy implementable solution when the laser-plasma accelerated beam requires optimization. In this paper, we report on a parametric study related to the transport of electron beams accelerated by laser-plasma interaction, using conventional accelerator elements and tools. We focus on both, high energy electron beams in the GeV range, as produced on petawatt (PW) class laser systems, and on lower energy electron beams in the hundreds of MeV range, as nowadays routinely obtained on commercially available multi-hundred TW laser systems. For both scenarios, our study allows understanding what are the crucial parameters that enable laser-plasma accelerators to compete with conventional ones and allow for a beam transport. We show that suitable working points require a tradeoff-combination between low beam divergence and narrow energy spread.« less

Assessment of tort liability risk management in the Virginia Department of Transportation : final report.

DOT National Transportation Integrated Search

1988-01-01

The Virginia Department of Transportation (VDOT) faces a growing tort liability problem. Under the Virginia Tort Claims Act, VOOT is liable for up to $75,000 for negligent or wrongful acts or omissions committed by its employees within the scope of t...

76 FR 9849 - Privacy Act of 1974: System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-22

... Public Law 105-178--enacted as the Transportation Equity Act for the 21st Century (TEA-21)--amends Section 31315 and Section 31136(e) of Title 49 of the U.S. Code. TEA-21 allows DOT to grant exemptions...(b)(3)] in the FMCSR. TEA-21 gives FMCSA broad authority to establish exemption application...

Predicting the Use of Public Transportation: A Case Study from Putrajaya, Malaysia

PubMed Central

Borhan, Muhamad Nazri; Mohd Akhir, Norliza; Mat Yazid, Muhamad Razuhanafi; Ismail, Amiruddin; Rahmat, Riza Atiq

2014-01-01

Putrajaya is a new federal administrative capital of Malaysia which has been set to achieve a 70% share of all travels by public transport in the city area. However, the current modal split between the public transport and private transport is 15 : 85. In order to understand travelers' willingness to use the public transport, a conceptual model has been developed to determine the factors that affect them to use the public transport instead of travelling in their own cars. Various variables such as service quality, environmental impact, attitude, and behavior intention were analyzed and tested using structural equation model (SEM). Results indicate that the service quality and attitude are found to have positive effects on the behavioral intention of taking the public transport. Other than this, this study also shows that the service quality and environmental impact have some positive influences on the attitude to using the public transport. However, environmental impact has no significant, positive, and direct effect on behavioral intention. The results of this study demonstrate that the model that was developed is useful in predicting the public transport and it could provide a more complete understanding of behavioral intention towards public transport use. PMID:25110744

Transport proteins of parasitic protists and their role in nutrient salvage.

PubMed

Dean, Paul; Major, Peter; Nakjang, Sirintra; Hirt, Robert P; Embley, T Martin

2014-01-01

The loss of key biosynthetic pathways is a common feature of important parasitic protists, making them heavily dependent on scavenging nutrients from their hosts. This is often mediated by specialized transporter proteins that ensure the nutritional requirements of the parasite are met. Over the past decade, the completion of several parasite genome projects has facilitated the identification of parasite transporter proteins. This has been complemented by functional characterization of individual transporters along with investigations into their importance for parasite survival. In this review, we summarize the current knowledge on transporters from parasitic protists and highlight commonalities and differences in the transporter repertoires of different parasitic species, with particular focus on characterized transporters that act at the host-pathogen interface.

Valley Forge alternative transportation feasibility study

DOT National Transportation Integrated Search

2004-06-01

NPS, as part of their General Management Plan (GMP) realignment, worked with Volpe to develop a series of alternative transportation methods in Valley Forge National Historical Park. Automobiles are the predominant means of transportation in the park...

The ACT transport: Panacea for the 80's or designer's illusion (panel discussion)

NASA Technical Reports Server (NTRS)

1976-01-01

A panel discussion was held which attempted to make an objective and pragmatic assessment of the standing of active control technology. The discussion focused on the standing of active control technology relative to civil air transport applications, the value as opposed to the cost of the projected benefits, the need for research, development, and demonstration, the role of government and industry in developing the technology, the major obstacles to its implementation, and the probable timing of the full utilization of active control technology in commercial transportation. An edited transcription of the prepared statements of the panel members and the subsequent open discussion between the panel and the audience is presented.

Transportation impact analysis gets a failing grade when it comes to climate change and smart growth

DOT National Transportation Integrated Search

2008-12-01

Transportation impact analysis performed to comply with environmental impact laws (i.e., the : California Environmental Quality Act or the National Environmental Policy Act) often focuses : on only one perspective about potential impacts. That perspe...