Using Focus Groups to Investigate the Presence of Formative Feedback in CAA

ERIC Educational Resources Information Center

Broughton, Stephen; Hernandez-Martinez, Paul; Robinson, Carol L.

2012-01-01

The aim of this project was to examine the effectiveness of feedback offered by computer-aided assessment (CAA). CAA provides practice tests for undergraduates, and feedback to help them improve their scores and mathematical understanding. However, there is a lack of evidence-based literature on the effect of formative feedback in mathematics…

Spinocerebellar ataxia 17: full phenotype in a 41 CAG/CAA repeats carrier.

PubMed

Origone, Paola; Gotta, Fabio; Lamp, Merit; Trevisan, Lucia; Geroldi, Alessandro; Massucco, Davide; Grazzini, Matteo; Massa, Federico; Ticconi, Flavia; Bauckneht, Matteo; Marchese, Roberta; Abbruzzese, Giovanni; Bellone, Emilia; Mandich, Paola

2018-01-01

Spinocerebellar ataxia 17 (SCA17) is one of the most heterogeneous forms of autosomal dominant cerebellar ataxias with a large clinical spectrum which can mimic other movement disorders such as Huntington disease (HD), dystonia and parkinsonism. SCA17 is caused by an expansion of CAG/CAA repeat in the Tata binding protein ( TBP ) gene. Normal alleles contain 25 to 40 CAG/CAA repeats, alleles with 50 or greater CAG/CAA repeats are pathological with full penetrance. Alleles with 43 to 49 CAG/CAA repeats were also reported and their penetrance is estimated between 50 and 80%. Recently few symptomatic individuals having 41 and 42 repeats were reported but it is still unclear whether CAG/CAA repeats of 41 or 42 are low penetrance disease-causing alleles. Thus, phenotypic variability like the disease course in subject with SCA17 locus restricted expansions remains to be fully understood. The patients was a 63-year-old woman who, at 54 years, showed personality changes and increased frequency of falls. At 55 years of age neuropsychological tests showed executive attention and visuospatial deficit. At the age of 59 the patient developed dysarthria and a progressive cognitive deficit. The neurological examination showed moderate gait ataxia, dysdiadochokinesia and dysmetria, dysphagia, dysarthria and abnormal saccadic pursuit, severe axial asynergy during postural changes, choreiform dyskinesias. Molecular analysis of the TBP gene demonstrated an allele with 41 repeat suggesting that 41 CAG/CCG TBP repeats could be an allele associated with the full clinical spectrum of SCA17. The described case with the other similar cases described in the literature suggests that 41 CAG/CAA trinucleotides should be considered as critical threshold in SCA17. We suggest that SCA17 diagnosis should be suspected in patients presenting with movement disorders associated with other neurodegenerative signs and symptoms.

Cross-talk between Aβ and endothelial SSAO/VAP-1 accelerates vascular damage and Aβ aggregation related to CAA-AD.

PubMed

Solé, Montse; Miñano-Molina, Alfredo J; Unzeta, Mercedes

2015-02-01

An association between semicarbazide-sensitive amine oxidase (SSAO) and cerebral amyloid angiopathy (CAA) related to Alzheimer's disease (AD) has been largely postulated. Increased SSAO activity and expression have been detected in cerebrovascular tissue and plasma of AD patients, colocalizing with cerebrovascular amyloid-beta (Aβ) deposits. As an enzyme, SSAO metabolizes primary amines generating hydrogen peroxide, ammonia, and aldehydes. The ability of these products to generate oxidative stress, to enhance the advanced glycation end-product generation, to promote the Aβ aggregation in vitro, and to induce apoptosis supports its role in CAA-related vascular pathology. However, whether the SSAO increase constitutes a cause or it is a consequence of the pathologic process has not been elucidated so far. To set up the nature of this relationship, vascular cell models expressing SSAO were treated with different Aβ forms, simulating the CAA conditions in vitro. It was found that the presence of the vasculotropic Dutch-mutated Aβ1-40 increases (Aβ1-40 D) the SSAO-dependent toxicity, which is accompanied by an increase of SSAO protein availability in endothelial cell membranes. In addition, SSAO enhances Aβ1-40 D and Aβ1-42 deposition on vascular cells by both activity-dependent and -independent mechanisms. Thus, we provide evidences indicating that Aβ itself could be one of the factors inducing SSAO increase in AD, enhancing its toxic effect, and inducing the vascular dysfunction and, in turn, that SSAO stimulates Aβ deposition on the vascular walls, thereby contributing to the CAA-AD progression. Therefore, molecules inhibiting SSAO could provide an alternative treatment for preventing/delaying the progress of CAA-AD-associated vasculopathy. Copyright © 2015 Elsevier Inc. All rights reserved.

Hybrid CFD/CAA Modeling for Liftoff Acoustic Predictions

NASA Technical Reports Server (NTRS)

Strutzenberg, Louise L.; Liever, Peter A.

2011-01-01

This paper presents development efforts at the NASA Marshall Space flight Center to establish a hybrid Computational Fluid Dynamics and Computational Aero-Acoustics (CFD/CAA) simulation system for launch vehicle liftoff acoustics environment analysis. Acoustic prediction engineering tools based on empirical jet acoustic strength and directivity models or scaled historical measurements are of limited value in efforts to proactively design and optimize launch vehicles and launch facility configurations for liftoff acoustics. CFD based modeling approaches are now able to capture the important details of vehicle specific plume flow environment, identifY the noise generation sources, and allow assessment of the influence of launch pad geometric details and sound mitigation measures such as water injection. However, CFD methodologies are numerically too dissipative to accurately capture the propagation of the acoustic waves in the large CFD models. The hybrid CFD/CAA approach combines the high-fidelity CFD analysis capable of identifYing the acoustic sources with a fast and efficient Boundary Element Method (BEM) that accurately propagates the acoustic field from the source locations. The BEM approach was chosen for its ability to properly account for reflections and scattering of acoustic waves from launch pad structures. The paper will present an overview of the technology components of the CFD/CAA framework and discuss plans for demonstration and validation against test data.

Utilizing the ultrasensitive Schistosoma up-converting phosphor lateral flow circulating anodic antigen (UCP-LF CAA) assay for sample pooling-strategies.

PubMed

Corstjens, Paul L A M; Hoekstra, Pytsje T; de Dood, Claudia J; van Dam, Govert J

2017-11-01

Methodological applications of the high sensitivity genus-specific Schistosoma CAA strip test, allowing detection of single worm active infections (ultimate sensitivity), are discussed for efficient utilization in sample pooling strategies. Besides relevant cost reduction, pooling of samples rather than individual testing can provide valuable data for large scale mapping, surveillance, and monitoring. The laboratory-based CAA strip test utilizes luminescent quantitative up-converting phosphor (UCP) reporter particles and a rapid user-friendly lateral flow (LF) assay format. The test includes a sample preparation step that permits virtually unlimited sample concentration with urine, reaching ultimate sensitivity (single worm detection) at 100% specificity. This facilitates testing large urine pools from many individuals with minimal loss of sensitivity and specificity. The test determines the average CAA level of the individuals in the pool thus indicating overall worm burden and prevalence. When requiring test results at the individual level, smaller pools need to be analysed with the pool-size based on expected prevalence or when unknown, on the average CAA level of a larger group; CAA negative pools do not require individual test results and thus reduce the number of tests. Straightforward pooling strategies indicate that at sub-population level the CAA strip test is an efficient assay for general mapping, identification of hotspots, determination of stratified infection levels, and accurate monitoring of mass drug administrations (MDA). At the individual level, the number of tests can be reduced i.e. in low endemic settings as the pool size can be increased as opposed to prevalence decrease. At the sub-population level, average CAA concentrations determined in urine pools can be an appropriate measure indicating worm burden. Pooling strategies allowing this type of large scale testing are feasible with the various CAA strip test formats and do not affect

Cardiolipin deficiency causes a dissociation of the b 6 c:caa 3 megacomplex in B. subtilis membranes.

PubMed

García Montes de Oca, Led Yered Jafet; Cabellos Avelar, Tecilli; Picón Garrido, Gerardo Ignacio; Chagoya-López, Alicia; González de la Vara, Luis; Delgado Buenrostro, Norma Laura; Chirino-López, Yolanda Irasema; Gómez-Lojero, Carlos; Gutiérrez-Cirlos, Emma Berta

2016-08-01

The associations among respiratory complexes in energy-transducing membranes have been established. In fact, it is known that the Gram-negative bacteria Paracoccus denitrificans and Escherichia coli have respiratory supercomplexes in their membranes. These supercomplexes are important for channeling substrates between enzymes in a metabolic pathway, and the assembly of these supercomplexes depends on the protein subunits and membrane lipids, mainly cardiolipin, which is present in both the mitochondrial inner membrane and bacterial membranes. The Gram-positive bacterium Bacillus subtilis has a branched respiratory chain, in which some complexes generate proton motive force whereas others constitute an escape valve of excess reducing power. Some peculiarities of this respiratory chain are the following: a type II NADH dehydrogenase, a unique b 6 c complex that has a b 6 type cytochrome with a covalently bound heme, and a c-type heme attached to the third subunit, which is similar to subunit IV of the photosynthetic b 6 f complex. Cytochrome c oxygen reductase (caa 3 ) contains a c-type cytochrome on subunit I. We previously showed that the b 6 c and the caa 3 complexes form a supercomplex. Both the b 6 c and the caa 3 together with the quinol oxygen reductase aa 3 generate the proton motive force in B. subtilis. In order to seek proof that this supercomplex is important for bacterial growth in aerobic conditions we compared the b 6 c: caa 3 supercomplex from wild type membranes with membranes from two mutants lacking cardiolipin. Both mutant complexes were found to have similar activity and heme content as the wild type. Clear native electrophoresis showed that mutants lacking cardiolipin had b 6 c:caa 3 supercomplexes of lower mass or even individual complexes after membrane solubilization with digitonin. The use of dodecyl maltoside revealed a more evident difference between wild-type and mutant supercomplexes. Here we provide evidence showing that cardiolipin

Effect of consecutive alternating administration (CAA) of a triple anti-enteroviral combination on Coxsackievirus B1 neuroinfection in mice.

PubMed

Stoyanova, Adelina; Nikolova, Ivanka; Galabov, Angel S

2015-09-01

Currently, clinically effective antivirals for use in the treatment of enteroviral (EV) infections do not exist. The main reason is the development of drug resistance, the principle obstacle in the development of EV infection chemotherapy, based til now on monotherapy. The most important achievement of our previous studies was the development of a novel scheme for in vivo application of a triple combination of EV inhibitors with different modes of action against Coxsackievirus B (CVB) infections in mice. It consists of consecutive alternating administration (CAA) of the substances in the combination. Here, we tested the effect of the triple combination pleconaril, guanidine-HCl, and oxoglaucine (PGO) via CAA in newborn mice infected with a neurotropic strain of CVB1 (20 LD50 per mouse). This combination manifested a considerable protective effect with pleconaril doses of 25-200mg/kg: it decreased mortality rate (protection index, PI, between 31.3% and 67.7%) and increased mean survival time (MST) by 4-6days. Pleconaril monotherapy demonstrated activity similar to that of PGO via CAA, as measured by PI values, but MST values were slightly lower. However, it also greatly suppressed growth of infected suckling mice, especially at 200mg/kg. This toxic effect was avoided with CAA of PGO at pleconaril doses of 25-100mg/kg. Pleconaril monotherapy administered every 3days was ineffective. The PGO with CAA treatment course decreased infectious virus content, whereas pleconaril monotherapy did not. Analysis of drug-sensitivity in brain samples from CVB1 infected mice, based on IC50 (50% inhibitory concentration) values from cell culture experiments, showed that the CAA course counteracted the development of drug resistance to pleconaril and oxoglaucine in the triple PGO combination and increased drug sensitivity. In contrast, pleconaril and oxoglaucine monotherapies resulted in drug resistance. This data clearly proves the effectiveness of the proposed novel approach-the CAA

Third Computational Aeroacoustics (CAA) Workshop on Benchmark Problems

NASA Technical Reports Server (NTRS)

Dahl, Milo D. (Editor)

2000-01-01

The proceedings of the Third Computational Aeroacoustics (CAA) Workshop on Benchmark Problems cosponsored by the Ohio Aerospace Institute and the NASA Glenn Research Center are the subject of this report. Fan noise was the chosen theme for this workshop with representative problems encompassing four of the six benchmark problem categories. The other two categories were related to jet noise and cavity noise. For the first time in this series of workshops, the computational results for the cavity noise problem were compared to experimental data. All the other problems had exact solutions, which are included in this report. The Workshop included a panel discussion by representatives of industry. The participants gave their views on the status of applying computational aeroacoustics to solve practical industry related problems and what issues need to be addressed to make CAA a robust design tool.

The cellulose synthase 3 (CesA3) gene of oomycetes: structure, phylogeny and influence on sensitivity to carboxylic acid amide (CAA) fungicides.

PubMed

Blum, Mathias; Gamper, Hannes A; Waldner, Maya; Sierotzki, Helge; Gisi, Ulrich

2012-04-01

Proper disease control is very important to minimize yield losses caused by oomycetes in many crops. Today, oomycete control is partially achieved by breeding for resistance, but mainly by application of single-site mode of action fungicides including the carboxylic acid amides (CAAs). Despite having mostly specific targets, fungicidal activity can differ even in species belonging to the same phylum but the underlying mechanisms are often poorly understood. In an attempt to elucidate the phylogenetic basis and underlying molecular mechanism of sensitivity and tolerance to CAAs, the cellulose synthase 3 (CesA3) gene was isolated and characterized, encoding the target site of this fungicide class. The CesA3 gene was present in all 25 species included in this study representing the orders Albuginales, Leptomitales, Peronosporales, Pythiales, Rhipidiales and Saprolegniales, and based on phylogenetic analyses, enabled good resolution of all the different taxonomic orders. Sensitivity assays using the CAA fungicide mandipropamid (MPD) demonstrated that only species belonging to the Peronosporales were inhibited by the fungicide. Molecular data provided evidence, that the observed difference in sensitivity to CAAs between Peronosporales and CAA tolerant species is most likely caused by an inherent amino acid configuration at position 1109 in CesA3 possibly affecting fungicide binding. The present study not only succeeded in linking CAA sensitivity of various oomycetes to the inherent CesA3 target site configuration, but could also relate it to the broader phylogenetic context. Copyright © 2012 The British Mycological Society. Published by Elsevier Ltd. All rights reserved.

Archive & Data Management Activities for ISRO Science Archives

NASA Astrophysics Data System (ADS)

Thakkar, Navita; Moorthi, Manthira; Gopala Krishna, Barla; Prashar, Ajay; Srinivasan, T. P.

2012-07-01

. For other AO payloads users can view the metadata and the data is available through FTP site. This same archival and dissemination strategy will be extended for the next moon mission Chandrayaan-2. ASTROSAT is going to be the first multi-wavelength astronomical mission for which the data is archived at ISSDC. It consists of five astronomical payloads that would allow simultaneous multi-wavelengths observations from X-ray to Ultra-Violet (UV) of astronomical objects. It is planned to archive the data sets in FITS. The archive of the ASTROSAT will be done in the Archive Layer at ISSDC. The Browse of the Archive will be available through the ISDA (Indian Science Data Archive) web site. The Browse will be IVOA compliant with a search mechanism using VOTable. The data will be available to the users only on request basis via a FTP site after the lock in period is over. It is planned that the Level2 pipeline software and various modules for processing the data sets will be also available on the web site. This paper, describes the archival procedure of Chandrayaan-1 and archive plan for the ASTROSAT, Chandrayaan-2 and other future mission of ISRO including the discussion on data management activities.

CFD-CAA Coupled Calculations of a Tandem Cylinder Configuration to Assess Facility Installation Effects

NASA Technical Reports Server (NTRS)

Redonnet, Stephane; Lockard, David P.; Khorrami, Mehdi R.; Choudhari, Meelan M.

2011-01-01

This paper presents a numerical assessment of acoustic installation effects in the tandem cylinder (TC) experiments conducted in the NASA Langley Quiet Flow Facility (QFF), an open-jet, anechoic wind tunnel. Calculations that couple the Computational Fluid Dynamics (CFD) and Computational Aeroacoustics (CAA) of the TC configuration within the QFF are conducted using the CFD simulation results previously obtained at NASA LaRC. The coupled simulations enable the assessment of installation effects associated with several specific features in the QFF facility that may have impacted the measured acoustic signature during the experiment. The CFD-CAA coupling is based on CFD data along a suitably chosen surface, and employs a technique that was recently improved to account for installed configurations involving acoustic backscatter into the CFD domain. First, a CFD-CAA calculation is conducted for an isolated TC configuration to assess the coupling approach, as well as to generate a reference solution for subsequent assessments of QFF installation effects. Direct comparisons between the CFD-CAA calculations associated with the various installed configurations allow the assessment of the effects of each component (nozzle, collector, etc.) or feature (confined vs. free jet flow, etc.) characterizing the NASA LaRC QFF facility.

CERA; Refiners can cope with CAA requirements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-02-17

This paper reports on a study conducted for the Department of Energy which predicts initial reformulated gasoline requirements in 1995 won't pose significant technical problems for U.S. refiners. But nearly all refiners will have to make added investments. Cambridge Energy Research Associates (CERA) prepared the study for DOE on critical issues affecting refiners and U.S. product supplies in the 1990s, particularly the effects of the 1990 Clean Air Act (CAA) amendments.

Clinical Characterization of Canine Acanthomatous Ameloblastoma (CAA) in 263 dogs and the Influence of Postsurgical Histopathological Margin on Local Recurrence.

PubMed

Goldschmidt, Stephanie L; Bell, Cindy M; Hetzel, Scott; Soukup, Jason

2017-12-01

Canine acanthomatous ameloblastoma (CAA) has been reported to be the most common odontogenic tumor in dogs. This retrospective study evaluated 263 dogs with histopathologically confirmed CAA. Within this data set, CAA presents most commonly in the rostral mandible in adult large breed dogs, with golden retriever dogs being overrepresented. Patients with appropriate follow-up after curative intent surgery were evaluated to assess the effect of histopathological margin on local tumor recurrence. No local recurrence was noted in any patient. This study raises questions about what the recommended surgical margin should be for treatment of CAA. It also serves as a stimulus for discussion as to whether further treatment for CAA is required when inadequate surgical margins are obtained, or if medical surveillance would be an appropriate management recommendation. Prospective studies are necessary to answer these questions.

Association of CAA and TATC Insertion/Deletion Genetic Polymorphisms in RTN4 3'-UTR with Hepatocellular Carcinoma Risk.

PubMed

Wang, NaNa; Chen, KeYu; Xu, Jia; Yuan, Fang; Li, HongYu; Deng, FengMei; Zhang, LuShun

2018-01-01

Evidence from recent researchers suggested that RTN4 is a multifunctional gene, including tumor suppression, apoptosis, vascular remodeling, and inhibition of axonal regeneration. The CAA and TATC insertion/deletion polymorphisms (CAA/TATC polymorphisms) of RTN4 3″-untranslated regions (UTRs) have been linked to cervical squamous cell carcinoma (CSCC), uterine leiomyomas (UL) and non-small cell lung cancer (NSCLC). However, the association between these two polymorphisms sites with Hepatocellular Carcinoma (HCC) risk was not carry out before. A total of 284 HCC patients and 484 control subjects were recruited for this study. The RTN4 CAA/TATC insertion/deletion genotypes were determined using polymerase chain reaction (PCR) assay. The ID/DD genotypes of CAA were significantly associated with an increased risk of HCC compared with the II genotype (ID vs. II: OR = 1.50, 95% CI: 1.10-2.04; DD vs. II: OR = 2.00, 95%CI: 1.15-3.46). Meanwhile, the frequency of D allele of CAA was significantly related with an increased risk of HCC compared with the I allele (D vs. I: OR = 1.39, 95% CI: 1.12-1.73). The ID genotypes of TATC was significantly associated with an increased risk of HCC compared with the DD genotype (ID vs. DD: OR = 1.70, 95% CI: 1.23-2.33). The present study provided evidence that RTN4 CAA/TATC polymorphisms were associated with HCC development in Chinese Han population.

Instability of expanded CAG/CAA repeats in spinocerebellar ataxia type 17.

PubMed

Gao, Rui; Matsuura, Tohru; Coolbaugh, Mary; Zühlke, Christine; Nakamura, Koichiro; Rasmussen, Astrid; Siciliano, Michael J; Ashizawa, Tetsuo; Lin, Xi

2008-02-01

Trinucleotide repeat expansions are dynamic mutations causing many neurological disorders, and their instability is influenced by multiple factors. Repeat configuration seems particularly important, and pure repeats are thought to be more unstable than interrupted repeats. But direct evidence is still lacking. Here, we presented strong support for this hypothesis from our studies on spinocerebellar ataxia type 17 (SCA17). SCA17 is a typical polyglutamine disease caused by CAG repeat expansion in TBP (TATA binding protein), and is unique in that the pure expanded polyglutamine tract is coded by either a simple configuration with long stretches of pure CAGs or a complex configuration containing CAA interruptions. By small pool PCR (SP-PCR) analysis of blood DNA from SCA17 patients of distinct racial backgrounds, we quantitatively assessed the instability of these two types of expanded alleles coding similar length of polyglutamine expansion. Mutation frequency in patients harboring pure CAG repeats is 2-3 folds of those with CAA interruptions. Interestingly, the pure CAG repeats showed both expansion and deletion while the interrupted repeats exhibited mostly deletion at a significantly lower frequency. These data strongly suggest that repeat configuration is a critical determinant for instability, and CAA interruptions might serve as a limiting element for further expansion of CAG repeats in SCA17 locus, suggesting a molecular basis for lack of anticipation in SCA17 families with interrupted CAG expansion.

The Hydrologic Cycle Distributed Active Archive Center

NASA Technical Reports Server (NTRS)

Hardin, Danny M.; Goodman, H. Michael

1995-01-01

The Marshall Space Flight Center Distributed Active Archive Center in Huntsville, Alabama supports the acquisition, production, archival and dissemination of data relevant to the study of the global hydrologic cycle. This paper describes the Hydrologic Cycle DAAC, surveys its principle data holdings, addresses future growth, and gives information for accessing the data sets.

Structure at 1.3 A resolution of Rhodothermus marinus caa(3) cytochrome c domain.

PubMed

Srinivasan, Vasundara; Rajendran, Chitra; Sousa, Filipa L; Melo, Ana M P; Saraiva, Lígia M; Pereira, Manuela M; Santana, Margarida; Teixeira, Miguel; Michel, Hartmut

2005-02-04

The cytochrome c domain of subunit II from the Rhodothermus marinus caa(3) HiPIP:oxygen oxidoreductase, a member of the superfamily of heme-copper-containing terminal oxidases, was produced in Escherichia coli and characterised. The recombinant protein, which shows the same optical absorption and redox properties as the corresponding domain in the holo enzyme, was crystallized and its structure was determined to a resolution of 1.3 A by the multiwavelength anomalous dispersion (MAD) technique using the anomalous dispersion of the heme iron atom. The model was refined to final R(cryst) and R(free) values of 13.9% and 16.7%, respectively. The structure reveals the insertion of two short antiparallel beta-strands forming a small beta-sheet, an interesting variation of the classical all alpha-helical cytochrome c fold. This modification appears to be common to all known caa(3)-type terminal oxidases, as judged by comparative modelling and by analyses of the available amino acid sequences for these enzymes. This is the first high-resolution crystal structure reported for a cytochrome c domain of a caa(3)-type terminal oxidase. The R.marinus caa(3) uses HiPIP as the redox partner. The calculation of the electrostatic potential at the molecular surface of this extra C-terminal domain provides insights into the binding to its redox partner on one side and its interaction with the remaining subunit II on the other side.

40 CFR 51.903 - How do the classification and attainment date provisions in section 181 of subpart 2 of the CAA...

Code of Federal Regulations, 2010 CFR

2010-07-01

... attainment date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? 51... date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? (a) In accordance with section 181(a)(1) of the CAA, each area subject to § 51.902(a) shall be classified by...

40 CFR 51.903 - How do the classification and attainment date provisions in section 181 of subpart 2 of the CAA...

Code of Federal Regulations, 2012 CFR

2012-07-01

... attainment date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? 51... date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? (a) In accordance with section 181(a)(1) of the CAA, each area subject to § 51.902(a) shall be classified by...

40 CFR 51.903 - How do the classification and attainment date provisions in section 181 of subpart 2 of the CAA...

Code of Federal Regulations, 2013 CFR

2013-07-01

... attainment date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? 51... date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? (a) In accordance with section 181(a)(1) of the CAA, each area subject to § 51.902(a) shall be classified by...

40 CFR 51.903 - How do the classification and attainment date provisions in section 181 of subpart 2 of the CAA...

Code of Federal Regulations, 2011 CFR

2011-07-01

... attainment date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? 51... date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? (a) In accordance with section 181(a)(1) of the CAA, each area subject to § 51.902(a) shall be classified by...

40 CFR 51.903 - How do the classification and attainment date provisions in section 181 of subpart 2 of the CAA...

Code of Federal Regulations, 2014 CFR

2014-07-01

... attainment date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? 51... date provisions in section 181 of subpart 2 of the CAA apply to areas subject to § 51.902(a)? (a) In accordance with section 181(a)(1) of the CAA, each area subject to § 51.902(a) shall be classified by...

CAA for Jet Noise Physics

NASA Technical Reports Server (NTRS)

Mankbadi, Reda

2001-01-01

Dr. Mankbadi summarized recent CAA results. Examples of the effect of various boundary condition schemes on the computed acoustic field, for a point source in a uniform flow, were shown. Solutions showing the impact of inflow excitations on the result were also shown. Results from a large eddy simulation, using a fourth-order MacCormack scheme with a Smagorinsky sub-grid turbulence model, were shown for a Mach 2.1 unheated jet. The results showed that the results were free from spurious modes. Results were shown for a Mach 1.4 jet using LES in the near field and the Kirchhoff method for the far field. Predicted flow field characteristics were shown to be in good agreement with data and predicted far field directivities were shown to be in qualitative agree with experimental measurements.

Human Factors Assessment of the UH-60M Common Avionics Architecture System (CAAS) Crew Station During the Limited User Evaluation (LEUE)

DTIC Science & Technology

2005-12-01

weapon system evaluation as a high-level architecture and distributed interactive simulation 6 compliant, human-in-the-loop, virtual environment...Directorate to participate in the Limited Early User Evaluation (LEUE) of the Common Avionics Architecture System (CAAS) cockpit. ARL conducted a human...CAAS, the UH-60M PO conducted a limited early user evaluation (LEUE) to evaluate the integration of the CAAS in the UH-60M crew station. The

Structure of caa(3) cytochrome c oxidase--a nature-made enzyme-substrate complex.

PubMed

Noor, Mohamed Radzi; Soulimane, Tewfik

2013-05-01

Aerobic respiration, the energetically most favorable metabolic reaction, depends on the action of terminal oxidases that include cytochrome c oxidases. The latter forms a part of the heme-copper oxidase superfamily and consists of three different families (A, B, and C types). The crystal structures of all families have now been determined, allowing a detailed structural comparison from evolutionary and functional perspectives. The A2-type oxidase, exemplified by the Thermus thermophilus caa(3) oxidase, contains the substrate cytochrome c covalently bound to the enzyme complex. In this article, we highlight the various features of caa(3) enzyme and provide a discussion of their importance, including the variations in the proton and electron transfer pathways.

Multidentate (18)F-polypegylated styrylpyridines as imaging agents for Aβ plaques in cerebral amyloid angiopathy (CAA).

PubMed

Zha, Zhihao; Choi, Seok Rye; Ploessl, Karl; Lieberman, Brian P; Qu, Wenchao; Hefti, Franz; Mintun, Mark; Skovronsky, Daniel; Kung, Hank F

2011-12-08

β-Amyloid plaques (Aβ plaques) in the brain are associated with cerebral amyloid angiopathy (CAA). Imaging agents that could target the Aβ plaques in the living human brain would be potentially valuable as biomarkers in patients with CAA. A new series of (18)F styrylpyridine derivatives with high molecular weights for selectively targeting Aβ plaques in the blood vessels of the brain but excluded from the brain parenchyma is reported. The styrylpyridine derivatives, 8a-c, display high binding affinities and specificity to Aβ plaques (K(i) = 2.87, 3.24, and 7.71 nM, respectively). In vitro autoradiography of [(18)F]8a shows labeling of β-amyloid plaques associated with blood vessel walls in human brain sections of subjects with CAA and also in the tissue of AD brain sections. The results suggest that [(18)F]8a may be a useful PET imaging agent for selectively detecting Aβ plaques associated with cerebral vessels in the living human brain.

2 CFR 1532.1110 - How will a CAA or CWA conviction affect my eligibility to participate in Federal contracts...

Code of Federal Regulations, 2010 CFR

2010-01-01

... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false How will a CAA or CWA conviction affect my eligibility to participate in Federal contracts, subcontracts, assistance, loans and other benefits? 1532.1110... the Clean Air Act and Clean Water Act § 1532.1110 How will a CAA or CWA conviction affect my...

Aβ-related angiitis: comparison with CAA without inflammation and primary CNS vasculitis.

PubMed

Salvarani, Carlo; Hunder, Gene G; Morris, Jonathan M; Brown, Robert D; Christianson, Teresa; Giannini, Caterina

2013-10-29

To analyze the clinical findings, response to therapy, and outcomes of patients with cerebral vascular amyloid-β (Aβ) deposition with and without inflammatory vascular infiltration. We report 78 consecutive patients with cerebral vascular Aβ deposition examined at Mayo Clinic Rochester over 25 years (1987 through 2011). Specimens reviewed by a neuropathologist showed 40 with vascular Aβ peptide without inflammation (cerebral amyloid angiopathy [CAA]), 28 with granulomatous vasculitis (Aβ-related angiitis or ABRA), and 10 with perivascular CAA-related inflammation. We also matched findings in 118 consecutive patients with primary CNS vasculitis (PCNSV) without Aβ seen over 25 years (1983 through 2007). Compared to the 40 with CAA, the 28 with ABRA were younger at diagnosis (p = 0.05), had less altered cognition (p = 0.02), fewer neurologic deficits (p = 0.02), and fewer intracranial hemorrhages (<0.001), but increased gadolinium leptomeningeal enhancement (p = 0.01) at presentation, and less mortality and disability at last follow-up (p < 0.001). Compared with PCNSV, the 28 patients with ABRA were older at diagnosis (p < 0.001), had a higher frequency of altered cognition (p = 0.05), seizures/spells (p = 0.006), gadolinium leptomeningeal enhancement (p < 0.001), and intracerebral hemorrhage (p = 0.02), lower frequency of hemiparesis (p = 0.01), visual symptoms (p = 0.04), and MRI evidence of cerebral infarction (p = 0.003), but higher CSF protein levels (p = 0.03). Results of treatment and outcomes in ABRA and PCNSV were similar. ABRA appears to represent a distinct subset of PCNSV.

Improved sensitivity of the urine CAA lateral-flow assay for diagnosing active Schistosoma infections by using larger sample volumes.

PubMed

Corstjens, Paul L A M; Nyakundi, Ruth K; de Dood, Claudia J; Kariuki, Thomas M; Ochola, Elizabeth A; Karanja, Diana M S; Mwinzi, Pauline N M; van Dam, Govert J

2015-04-22

Accurate determination of Schistosoma infection rates in low endemic regions to examine progress towards interruption of transmission and elimination requires highly sensitive diagnostic tools. An existing lateral flow (LF) based test demonstrating ongoing infections through detection of worm circulating anodic antigen (CAA), was improved for sensitivity through implementation of a protocol allowing increased sample input. Urine is the preferred sample as collection is non-invasive and sample volume is generally not a restriction. Centrifugal filtration devices provided a method to concentrate supernatant of urine samples extracted with trichloroacetic acid (TCA). For field trials a practical sample volume of 2 mL urine allowed detection of CAA down to 0.3 pg/mL. The method was evaluated on a set of urine samples (n = 113) from an S. mansoni endemic region (Kisumu, Kenya) and compared to stool microscopy (Kato Katz, KK). In this analysis true positivity was defined as a sample with either a positive KK or UCAA test. Implementation of the concentration method increased clinical sensitivity (Sn) from 44 to 98% when moving from the standard 10 μL (UCAA10 assay) to 2000 μL (UCAA2000 assay) urine sample input. Sn for KK varied between 23 and 35% for a duplicate KK (single stool, two slides) to 52% for a six-fold KK (three consecutive day stools, two slides). The UCAA2000 assay indicated 47 positive samples with CAA concentration above 0.3 pg/mL. The six-fold KK detected 25 egg positives; 1 sample with 2 eggs detected in the 6-fold KK was not identified with the UCAA2000 assay. Larger sample input increased Sn of the UCAA assay to a level indicating 'true' infection. Only a single 2 mL urine sample is needed, but analysing larger sample volumes could still increase test accuracy. The UCAA2000 test is an appropriate candidate for accurate identification of all infected individuals in low-endemic regions. Assay materials do not require refrigeration and collected

Determination of the specificity of monoclonal antibodies against Schistosoma mansoni CAA glycoprotein antigen using neoglycoconjugate variants.

PubMed

Carvalho de Souza, Adriana; van Remoortere, Alexandra; Hokke, Cornelis H; Deelder, André M; Vliegenthart, Johannes F G; Kamerling, Johannis P

2005-09-01

The immunogenic O-glycan of circulating anodic antigen (CAA) is a high-molecular-mass polysaccharide with the unique -->6)-[beta-D-GlcpA-(1-->3)]-beta-D-GalpNAc-(1--> repeating unit. To obtain information at the molecular level about the specificity of monoclonal antibodies against CAA, the immunoreactivity of two series of bovine serum albumin-coupled synthetic oligosaccharides related to the CAA O-glycan was monitored using ELISA and surface plasmon resonance spectroscopy. The importance of the axial hydroxyl group of beta-D-GalpNAc for antibody binding was investigated using the following series of analogues: beta-D-GlcpA-(1-->3)-beta-D-GlcpNAc-(1-->O); beta-D-GlcpNAc-(1-->6)-[beta-D-GlcpA-(1-->3)]-beta-D-GlcpNAc-(1-->O); and beta-D-GlcpA-(1-->3)-beta-D-GlcpNAc-(1-->6)-[beta-D-GlcpA-(1-->3)]-beta-D-GlcpNAc-(1-->O). In the second series of analogues, beta-D-Glcp6S-(1-->3)-beta-D-GalpNAc-(1-->O), beta-D-GalpNAc-(1-->6)-[beta-D-Glcp6S-(1-->3)]-beta-D-GalpNAc-(1-->O), and beta-D-Glcp6S-(1-->3)-beta-D-Gal-pNAc-(1-->6)-[beta-D-Glcp6S-(1-->3)]-beta-D-GalpNAc-(1-->O), the native beta-D-GlcpA moiety was replaced by beta-D-Glcp6S to evaluate the influence of the nature of the charge on antibody recognition. Comparison of the immunoreactivity of these series with that measured for conjugates containing corresponding synthetic CAA fragments showed that the antibody binding levels can be correlated to the antibody specificity to CAA fragments. For the most reactive antibodies, the structural changes chosen (beta-D-GalpNAc replaced by beta-D-GlcpNAc, and beta-D-GlcpA replaced by beta-D-Glcp6S) completely eradicated the binding.

Intravenous injection of beta-amyloid seeds promotes cerebral amyloid angiopathy (CAA).

PubMed

Burwinkel, Michael; Lutzenberger, Manuel; Heppner, Frank L; Schulz-Schaeffer, Walter; Baier, Michael

2018-03-05

Seeding and spread of beta-amyloid (Aβ) pathologies have been considered to be based on prion-like mechanisms. However, limited transmissibility of Aβ seeding activity upon peripheral exposure would represent a key difference to prions, not only in terms of pathogenesis but also in terms of potential transmission of disease. We partially characterized the seeded Aβ amyloidosis after intracerebral injection of various brain homogenates in APP/PS1 mice. One particularly seed-laden homogenate was selected to investigate the development of Aβ pathologies after intravenous exposure. We report here that a single intravenous injection of an Alzheimer disease patient's-brain extract into APP/PS1 recipient mice led to cerebral amyloid angiopathy within 180 days post injection. Thus, vascular proteinopathies such as CAA are transmissible in mice via the intravenous route of peripheral exposure.

ACB-PCR measurement of spontaneous and furan-induced H-ras codon 61 CAA to CTA and CAA to AAA mutation in B6C3F1 mouse liver.

PubMed

Banda, Malathi; Recio, Leslie; Parsons, Barbara L

2013-10-01

Furan is a rodent liver carcinogen, but the mode of action for furan hepatocarcinogenicity is unclear. H-ras codon 61 mutations have been detected in spontaneous liver tumors of B6C3F1 mice, and the fraction of liver tumors carrying H-ras codon 61 CAA to AAA mutation increased in furan-treated mice. Allele-specific competitive blocker PCR (ACB-PCR) has been used previously to quantify early, carcinogen-induced increases in tumor-associated mutations. The present pilot study investigated whether furan drives clonal expansion of pre-existing H-ras mutant cells in B6C3F1 mouse liver. H-ras codon 61 CAA to CTA and CAA to AAA mutations were measured in DNA isolated from liver tissue of female mice treated with 0, 1, 2, 4, or 8 mg furan/kg body weight, five days per week for three weeks, using five mice per treatment group. Spontaneous levels of mutation were low, with two of five control mice having an H-ras codon 61 CTA or AAA mutant fraction (MF) greater than 10(-5) . Several furan-treated mice had H-ras codon 61 AAA or CTA MFs greater than those measured in control mice and lower bound estimates of induced MF were calculated. However, no statistically-significant differences were observed between treatment groups. Therefore, while sustained exposure to furan is carcinogenic, at the early stage of carcinogenesis examined in this study (three weeks), there was not a significant expansion of H-ras mutant cells. Copyright © 2013 Wiley Periodicals, Inc.

Contents of the JPL Distributed Active Archive Center (DAAC) archive, version 2-91

NASA Technical Reports Server (NTRS)

Smith, Elizabeth A. (Editor); Lassanyi, Ruby A. (Editor)

1991-01-01

The Distributed Active Archive Center (DAAC) archive at the Jet Propulsion Laboratory (JPL) includes satellite data sets for the ocean sciences and global change research to facilitate multidisciplinary use of satellite ocean data. Parameters include sea surface height, surface wind vector, sea surface temperature, atmospheric liquid water, and surface pigment concentration. The Jet Propulsion Laboratory DAAC is an element of the Earth Observing System Data and Information System (EOSDIS) and will be the United States distribution site for the Ocean Topography Experiment (TOPEX)/POSEIDON data and metadata.

40 CFR 51.1103 - Application of classification and attainment date provisions in CAA section 181 of subpart 2 to...

Code of Federal Regulations, 2012 CFR

2012-07-01

... attainment date provisions in CAA section 181 of subpart 2 to areas subject to § 51.1102(a). 51.1103 Section... attainment date provisions in CAA section 181 of subpart 2 to areas subject to § 51.1102(a). (a) In... Ozone NAAQS (0.075 ppm) for Areas Subject to Section 51.1102(a) Area class 8-hour design value(ppm ozone...

40 CFR 51.1103 - Application of classification and attainment date provisions in CAA section 181 of subpart 2 to...

Code of Federal Regulations, 2014 CFR

2014-07-01

... attainment date provisions in CAA section 181 of subpart 2 to areas subject to § 51.1102(a). 51.1103 Section... attainment date provisions in CAA section 181 of subpart 2 to areas subject to § 51.1102(a). (a) In... Ozone NAAQS (0.075 ppm) for Areas Subject to Section 51.1102(a) Area class 8-hour design value(ppm ozone...

40 CFR 51.1103 - Application of classification and attainment date provisions in CAA section 181 of subpart 2 to...

Code of Federal Regulations, 2013 CFR

2013-07-01

... attainment date provisions in CAA section 181 of subpart 2 to areas subject to § 51.1102(a). 51.1103 Section... attainment date provisions in CAA section 181 of subpart 2 to areas subject to § 51.1102(a). (a) In... Ozone NAAQS (0.075 ppm) for Areas Subject to Section 51.1102(a) Area class 8-hour design value(ppm ozone...

Distributed Active Archive Center

NASA Technical Reports Server (NTRS)

Bodden, Lee; Pease, Phil; Bedet, Jean-Jacques; Rosen, Wayne

1993-01-01

The Goddard Space Flight Center Version 0 Distributed Active Archive Center (GSFC V0 DAAC) is being developed to enhance and improve scientific research and productivity by consolidating access to remote sensor earth science data in the pre-EOS time frame. In cooperation with scientists from the science labs at GSFC, other NASA facilities, universities, and other government agencies, the DAAC will support data acquisition, validation, archive and distribution. The DAAC is being developed in response to EOSDIS Project Functional Requirements as well as from requirements originating from individual science projects such as SeaWiFS, Meteor3/TOMS2, AVHRR Pathfinder, TOVS Pathfinder, and UARS. The GSFC V0 DAAC has begun operational support for the AVHRR Pathfinder (as of April, 1993), TOVS Pathfinder (as of July, 1993) and the UARS (September, 1993) Projects, and is preparing to provide operational support for SeaWiFS (August, 1994) data. The GSFC V0 DAAC has also incorporated the existing data, services, and functionality of the DAAC/Climate, DAAC/Land, and the Coastal Zone Color Scanner (CZCS) Systems.

40 CFR 51.126 - Determination of widespread use of ORVR and waiver of CAA section 182(b)(3) Stage II gasoline...

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 2 2012-07-01 2012-07-01 false Determination of widespread use of ORVR and waiver of CAA section 182(b)(3) Stage II gasoline vapor recovery requirements. 51.126 Section 51... Determination of widespread use of ORVR and waiver of CAA section 182(b)(3) Stage II gasoline vapor recovery...

SysML model of exoplanet archive functionality and activities

NASA Astrophysics Data System (ADS)

Ramirez, Solange

2016-08-01

The NASA Exoplanet Archive is an online service that serves data and information on exoplanets and their host stars to help astronomical research related to search for and characterization of extra-solar planetary systems. In order to provide the most up to date data sets to the users, the exoplanet archive performs weekly updates that include additions into the database and updates to the services as needed. These weekly updates are complex due to interfaces within the archive. I will be presenting a SysML model that helps us perform these update activities in a weekly basis.

The Land Processes Distributed Active Archive Center (LP DAAC)

USGS Publications Warehouse

Golon, Danielle K.

2016-10-03

The Land Processes Distributed Active Archive Center (LP DAAC) operates as a partnership with the U.S. Geological Survey and is 1 of 12 DAACs within the National Aeronautics and Space Administration (NASA) Earth Observing System Data and Information System (EOSDIS). The LP DAAC ingests, archives, processes, and distributes NASA Earth science remote sensing data. These data are provided to the public at no charge. Data distributed by the LP DAAC provide information about Earth’s surface from daily to yearly intervals and at 15 to 5,600 meter spatial resolution. Data provided by the LP DAAC can be used to study changes in agriculture, vegetation, ecosystems, elevation, and much more. The LP DAAC provides several ways to access, process, and interact with these data. In addition, the LP DAAC is actively archiving new datasets to provide users with a variety of data to study the Earth.

Rocky Flats CAAS System Recalibrated, Retested, and Analyzed to Install in the Criticality Experiments Facility at the Nevada Test Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, S; Heinrichs, D; Biswas, D

2009-05-27

Neutron detectors and control panels transferred from the Rocky Flats Plant (RFP) were recalibrated and retested for redeployment to the CEF. Testing and calibration were successful with no failure to any equipment. Detector sensitivity was tested at a TRIGA reactor, and the response to thermal neutron flux was satisfactory. MCNP calculated minimum fission yield ({approx} 2 x 10{sup 15} fissions) was applied to determine the thermal flux at selected detector positions at the CEF. Thermal flux levels were greater than 6.39 x 10{sup 6} (n/cm{sup 2}-sec), which was about four orders of magnitude greater than the minimum alarm flux. Calculationsmore » of detector survivable distances indicate that, to be out of lethal area, a detector needs to be placed greater than 15 ft away from a maximum credible source. MCNP calculated flux/dose results were independently verified by COG. CAAS calibration and the testing confirmed that the RFP CAAS system is performing its functions as expected. New criteria for the CAAS detector placement and 12-rad zone boundaries at the CEF are established. All of the CAAS related documents and hardware have been transferred from LLNL to NSTec for installation at the CEF high bay areas.« less

Characterization of CAA0225, a novel inhibitor specific for cathepsin L, as a probe for autophagic proteolysis.

PubMed

Takahashi, Katsuyuki; Ueno, Takashi; Tanida, Isei; Minematsu-Ikeguchi, Naoko; Murata, Mitsuo; Kominami, Eiki

2009-03-01

We screened a series of new epoxysuccinyl peptides for the development of a lysosomal cathepsin L-specific inhibitor. Among the compounds tested, (2S,3S)-oxirane-2,3-dicarboxylic acid 2-[((S)-1-benzylcarbamoyl-2-phenyl-ethyl)-amide] 3-{[2-(4-hydroxy-phenyl)-ethyl]-amide} (compound CAA0225) was the most potent inhibitor of cathepsin L. CAA0225 inhibited rat liver cathepsin L with IC50 values of 1.9 nM, but not rat liver cathepsin B (IC50, >1000-5000 nM). To assess the contribution of cathepsin L to lysosomal proteolysis, we evaluated autophagy, which is the process of lysosomal self-degradation of cell constituents. In HeLa and Huh-7 cells cultured under nutrient-deprived conditions CAA0225 significantly inhibited degradation of long-lived proteins; however, the magnitude of inhibition was comparable to that in the presence of CA-074-OMe, which is a cathepsin B-specific inhibitor. Thus the contributions of cathepsin L and cathepsin B to autophagic protein degradation of cytoplasmic proteins are nearly equal. During autophagy, microtubule-associated protein IA/IB light chain 3-II (LC3-II) and gamma-aminobutyric acid (A) receptor-associated protein (GABARAP)-II, which are specific markers of autophagosomal membranes that engulf cytoplasmic components, also undergo degradation upon fusion of autophagosomes with lysosomes. CAA0225 effectively inhibited degradation of LC3-II and GABARAP, whereas CA-074-OMe had only a marginal effect on their levels. Therefore we conclude that cathepsin L does not play a general role in the degradation of proteins in the lumen of autophagosomes, but rather is involved specifically in the degradation of autophagosomal membrane markers.

Association of the GGCX (CAA)16/17 repeat polymorphism with higher warfarin dose requirements in African Americans.

PubMed

Cavallari, Larisa H; Perera, Minoli; Wadelius, Mia; Deloukas, Panos; Taube, Gelson; Patel, Shitalben R; Aquino-Michaels, Keston; Viana, Marlos A G; Shapiro, Nancy L; Nutescu, Edith A

2012-02-01

Little is known about genetic contributors to higher than usual warfarin dose requirements, particularly for African Americans. This study tested the hypothesis that the γ-glutamyl carboxylase (GGCX) genotype contributes to warfarin dose requirements greater than 7.5 mg/day in an African American population. A total of 338 African Americans on a stable dose of warfarin were enrolled. The GGCX rs10654848 (CAA)n, rs12714145 (G>A), and rs699664 (p.R325Q); VKORC1 c.-1639G>A and rs61162043; and CYP2C9*2, *3, *5, *8, *11, and rs7089580 genotypes were tested for their association with dose requirements greater than 7.5 mg/day alone and in the context of other variables known to influence dose variability. The GGCX rs10654848 (CAA)16 or 17 repeat occurred at a frequency of 2.6% in African Americans and was overrepresented among patients requiring greater than 7.5 mg/day versus those who required lower doses (12 vs. 3%, P=0.003; odds ratio 4.0, 95% confidence interval, 1.5-10.5). The GGCX rs10654848 genotype remained associated with high dose requirements on regression analysis including age, body size, and VKORC1 genotype. On linear regression, the GGCX rs10654848 genotype explained 2% of the overall variability in warfarin dose in African Americans. An examination of the GGCX rs10654848 genotype in warfarin-treated Caucasians revealed a (CAA)16 repeat frequency of only 0.27% (P=0.008 compared with African Americans). These data support the GGCX rs10654848 genotype as a predictor of higher than usual warfarin doses in African Americans, who have a 10-fold higher frequency of the (CAA)16/17 repeat compared with Caucasians.

Land processes distributed active archive center product lifecycle plan

USGS Publications Warehouse

Daucsavage, John C.; Bennett, Stacie D.

2014-01-01

The U.S. Geological Survey (USGS) Earth Resources Observation and Science (EROS) Center and the National Aeronautics and Space Administration (NASA) Earth Science Data System Program worked together to establish, develop, and operate the Land Processes (LP) Distributed Active Archive Center (DAAC) to provide stewardship for NASA’s land processes science data. These data are critical science assets that serve the land processes science community with potential value beyond any immediate research use, and therefore need to be accounted for and properly managed throughout their lifecycle. A fundamental LP DAAC objective is to enable permanent preservation of these data and information products. The LP DAAC accomplishes this by bridging data producers and permanent archival resources while providing intermediate archive services for data and information products.

Insights into the molecular mechanism of tolerance to carboxylic acid amide (CAA) fungicides in Pythium aphanidermatum.

PubMed

Blum, Mathias; Gisi, Ulrich

2012-08-01

Tolerance to the oomycete-specific carboxylic acid amide (CAA) fungicides is a poorly understood mechanism in Pythium species. The root-rot and damping-off causative agent Pythium aphanidermatum and the CAA fungicide mandipropamid (MPD) were used to investigate the molecular basis of CAA tolerance. Five genes putatively involved in carbohydrate synthesis were identified and characterised: one chitin synthase gene, PaChs, and four cellulose synthase genes PaCesA1 to PaCesA4, of which PaCesA3 encodes the MPD target enzyme. These genes were differentially expressed throughout the life cycle of P. aphanidermatum. Mycelium treated with MPD concentrations slightly affecting mycelial growth did not cause a change in PaCesA3 expression nor a strong upregulation of PaCesA homologues. The high tolerance level of P. aphanidermatum and the lack of PaCesA upregulation imply that MPD tolerance is the result of a specific amino acid configuration in the cellulose synthase 3 (CesA3) target enzyme. Indeed, P. aphanidermatum displays the amino acid L1109 which is also associated with MPD resistance in artificial mutants of Phytophthora species. It is concluded that MPD tolerance in P. aphanidermatum is not caused by compensatory mechanisms but most likely by an inherent target-site configuration in PaCesA3 that hinders MPD binding to the enzyme pocket. Copyright © 2012 Society of Chemical Industry.

PolyQ repeat expansions in ATXN2 associated with ALS are CAA interrupted repeats.

PubMed

Yu, Zhenming; Zhu, Yongqing; Chen-Plotkin, Alice S; Clay-Falcone, Dana; McCluskey, Leo; Elman, Lauren; Kalb, Robert G; Trojanowski, John Q; Lee, Virginia M-Y; Van Deerlin, Vivianna M; Gitler, Aaron D; Bonini, Nancy M

2011-03-29

Amyotrophic lateral sclerosis (ALS) is a devastating, rapidly progressive disease leading to paralysis and death. Recently, intermediate length polyglutamine (polyQ) repeats of 27-33 in ATAXIN-2 (ATXN2), encoding the ATXN2 protein, were found to increase risk for ALS. In ATXN2, polyQ expansions of ≥ 34, which are pure CAG repeat expansions, cause spinocerebellar ataxia type 2. However, similar length expansions that are interrupted with other codons, can present atypically with parkinsonism, suggesting that configuration of the repeat sequence plays an important role in disease manifestation in ATXN2 polyQ expansion diseases. Here we determined whether the expansions in ATXN2 associated with ALS were pure or interrupted CAG repeats, and defined single nucleotide polymorphisms (SNPs) rs695871 and rs695872 in exon 1 of the gene, to assess haplotype association. We found that the expanded repeat alleles of 40 ALS patients and 9 long-repeat length controls were all interrupted, bearing 1-3 CAA codons within the CAG repeat. 21/21 expanded ALS chromosomes with 3CAA interruptions arose from one haplotype (GT), while 18/19 expanded ALS chromosomes with <3CAA interruptions arose from a different haplotype (CC). Moreover, age of disease onset was significantly earlier in patients bearing 3 interruptions vs fewer, and was distinct between haplotypes. These results indicate that CAG repeat expansions in ATXN2 associated with ALS are uniformly interrupted repeats and that the nature of the repeat sequence and haplotype, as well as length of polyQ repeat, may play a role in the neurological effect conferred by expansions in ATXN2.

Factors associated with ATXN2 CAG/CAA repeat intergenerational instability in Spinocerebellar Ataxia type 2.

PubMed

Almaguer-Mederos, L E; Mesa, J M L; González-Zaldívar, Y; Almaguer-Gotay, D; Cuello-Almarales, D; Aguilera-Rodríguez, R; Falcón, N S; Gispert, S; Auburger, G; Velázquez-Pérez, L

2018-05-14

Spinocerebellar ataxia type 2 (SCA2) is a neurodegenerative disorder caused by the unstable expansion of a CAG/CAA repeat in the ATXN2 gene, which normally encodes 22 glutamines (Q22). A large study was conducted to characterize the CAG/CAA repeat intergenerational instability in SCA2 families. Large normal alleles (LNA, Q24-31) were significantly more unstable upon maternal transmissions. In contrast, expanded alleles (EA, Q32-750) were significantly more unstable during paternal transmissions, in correlation with repeat length. Significant correlations were found between the instability and the age at conception in paternal transmissions. In conclusion, intergenerational instability at ATXN2 locus is influenced by the sex, repeat length and age at conception of the transmitting parent. These results have profound implications for genetic counseling services. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

The Correlation Between Pre and Postoperative Hearing Level with High Resolution Computed Tomography (HRCT) Findings in Congenital Canal Atresia (CAA) Patients.

PubMed

Asma, A; Abdul Fatah, A W; Hamzaini, A H; Mazita, A

2013-12-01

In managing patient with congenital congenital aural atresia (CAA), preoperative high resolution computed tomography (HRCT) scan and hearing assessment are important. A grading system based on HRCT findings was first introduced by Jahrsdoefer in order to select appropriate candidates for operation and to predict the postoperative hearing outcome in CAA patients. The score of eight and more was considered as a good prognostic factor for hearing reconstruction surgery. However previously in our center this score was not used as the criteria for surgical procedure. This study was conducted at Center A to evaluate the correlation between pre and postoperative hearing level with HRCT based on a Jahrsdoefer grading system in patients with CAA. All records and HRCT films with CAA from January 1997 until December 2007 at Center A were evaluated. The demographic data, operative records, pre and post operative hearing levels and HRCT findings were analyzed. Hearing level in this study was based on a pure tone average of air-bone gap at 500 Hz, 1 kHz and 2 kHz or hearing level obtained from auditory brainstem response eudiometry. This study was approved by Research Ethics Committee (code number, FF-197-2008). Thirty-two ears were retrospectively evaluated. The postoperative hearing level of 30 dB and less was considered as successful hearing result postoperatively. Of the six ears which underwent canalplasty, three had achieved successful hearing result. However, there was no significant correlation between preoperative hearing level (HL) with HRCT score and postoperative HL with HRCT score at 0.05 significant levels (correlation coefficient = -0.292, P = 0.105 and correlation coefficient = -0.127, P = 0.810) respectively. Hearing evaluation and HRCT temporal bone are two independent evaluations for the patients with CAA before going for hearing reconstructive surgery.

The chloroplast division mutant caa33 of Arabidopsis thaliana reveals a crucial impact of chloroplast homeostasis on stress acclimation and retrograde plastid-to-nucleus signaling

PubMed Central

Šimková, Klára; Kim, Chanhong; Gacek, Katarzyna; Baruah, Aiswarya; Laloi, Christophe; Apel, Klaus

2011-01-01

SUMMARY Retrograde plastid-to-nucleus signaling tightly controls and coordinates nuclear and plastid gene expression that is required for plastid biogenesis and chloroplast activities. As chloroplasts act as sensors of environmental changes, plastid-derived signaling also modulates stress responses of plants by transferring stress-related signals and altering nuclear gene expression. Various mutant screens have been undertaken to identify constituents of plastid signaling pathways. Almost all mutations identified in these screens have in common that they target plastid-specific but not extra-plastidic functions. They have been suggested to define either genuine constituents of retrograde signaling pathways or components required for the synthesis of plastid signals. Here we report the characterization of the caa33 (constitutive activator of AAA-ATPase) mutant, which reveals another way of how mutations that affect plastid functions may modulate retrograde plastid signaling. caa33 disturbs a plastid-specific function by impeding plastid division thereby perturbing plastid homeostasis. This results in pre-conditioning plants by activating the expression of stress genes, enhancing pathogen resistance and attenuating the plant’s capacity to respond to plastid signals. Our study reveals an intimate link between chloroplast activity and the plant’s susceptibility to stress and emphasizes the need to consider the possible impact of pre-conditioning on retrograde plastid-to-nucleus signaling. PMID:22014227

Planetary Data Archiving Activities of ISRO

NASA Astrophysics Data System (ADS)

Gopala Krishna, Barla; D, Rao J.; Thakkar, Navita; Prashar, Ajay; Manthira Moorthi, S.

composition & mineralogy of mars, Mars Exospheric Neutral Composition Analyser (MENCA) to study the composition and density of the Martian neutral atmosphere and Lyman Alpha Photometer (LAP) to investigate the loss process of water in Martian atmosphere, towards fulfilling the mission objectives. Active archive created in PDS for some of the instrument data during the earth phase of the mission is being analysed by the PIs. The Mars science data from the onboard instruments is expected during September 2014. The next planetary mission planned to moon is Chandrayaan-2 which consists of an orbiter having five instruments (http://www.isro.org) viz, (i) Imaging IR Spectrometer (IIRS) for mineral mapping, (ii) TMC-2 for topographic mapping, (iii) MiniSAR to detect water ice in the permanently shadowed regions on the Lunar poles, up to a depth of a few meters, (iv) Large Area Soft X-ray spectrometer (CLASS) & Solar X-ray Monitor (XSM) for mapping the major elements present on the lunar surface and (v)Neutral Mass Spectrometer (ChACE2) to carry out a detailed study of the lunar exosphere towards moon exploration; a rover for some specific experiments and a Lander for technology experiment and demonstration. The data is planned to be archived in PDS standards.

Least-Squares Spectral Element Solutions to the CAA Workshop Benchmark Problems

NASA Technical Reports Server (NTRS)

Lin, Wen H.; Chan, Daniel C.

1997-01-01

This paper presents computed results for some of the CAA benchmark problems via the acoustic solver developed at Rocketdyne CFD Technology Center under the corporate agreement between Boeing North American, Inc. and NASA for the Aerospace Industry Technology Program. The calculations are considered as benchmark testing of the functionality, accuracy, and performance of the solver. Results of these computations demonstrate that the solver is capable of solving the propagation of aeroacoustic signals. Testing of sound generation and on more realistic problems is now pursued for the industrial applications of this solver. Numerical calculations were performed for the second problem of Category 1 of the current workshop problems for an acoustic pulse scattered from a rigid circular cylinder, and for two of the first CAA workshop problems, i. e., the first problem of Category 1 for the propagation of a linear wave and the first problem of Category 4 for an acoustic pulse reflected from a rigid wall in a uniform flow of Mach 0.5. The aim for including the last two problems in this workshop is to test the effectiveness of some boundary conditions set up in the solver. Numerical results of the last two benchmark problems have been compared with their corresponding exact solutions and the comparisons are excellent. This demonstrates the high fidelity of the solver in handling wave propagation problems. This feature lends the method quite attractive in developing a computational acoustic solver for calculating the aero/hydrodynamic noise in a violent flow environment.

Determining Antioxidant Activities of Lactobacilli Cell-Free Supernatants by Cellular Antioxidant Assay: A Comparison with Traditional Methods

PubMed Central

Xing, Jiali; Wang, Gang; Zhang, Qiuxiang; Liu, Xiaoming; Gu, Zhennan; Zhang, Hao; Chen, Yong Q.; Chen, Wei

2015-01-01

Antioxidant activity of lactic acid bacteria is associated with multiple health-protective effects. Traditional indexes of chemical antioxidant activities poorly reflect the antioxidant effects of these bacteria in vivo. Cellular antioxidant activity (CAA) assay was used in this study to determine the antioxidant activity of cell-free supernatants (CFSs) of 10 Lactobacillus strains. The performance of the CAA assay was compared with that of four chemical antioxidant activity assays, namely, DPPH radical scavenging, hydroxyl radical scavenging (HRS), reducing power (RP), and inhibition of linoleic acid peroxidation (ILAP). Results of the CAA assay were associated with those of DPPH and ILAP assays, but not with those of RP and HRS assays. The inter- and intra-specific antioxidant activities of CFS were characterized by chemical and CAA assays. L. rhamnosus CCFM 1107 displayed a high antioxidative effect similar to positive control L. rhamnosus GG ATCC 53103 in all of the assays. The CAA assay is a potential method for the detection of antioxidant activities of lactobacilli CFSs. PMID:25789875

CAA for Jet Noise Physics: Issues and Recent Progress

NASA Technical Reports Server (NTRS)

Mankbadi, Reda

2001-01-01

Dr. Mankbadi summarized recent CAA results. Examples of the effect of various boundary condition schemes on the computed acoustic field, for a point source in a uniform flow, were shown. Solutions showing the impact of inflow excitations on the result were also shown. Results from a large eddy simulation, using a fourth-order MacCormack scheme with a Smagorinsky sub-grid turbulence model, were shown for a Mach 2.1 unheated jet. The results showed that the results were free from spurious modes. Results were shown for a Mach 1.4 jet using LES in the near field and the Kirchhoff method for the far field. Predicted flow field characteristics were shown to be in good agreement with data and predicted far field directivities were shown to be in qualitative agree with experimental measurements.

A modular Human Exposure Model (HEM) framework to characterize near-field chemical exposure in LCIA and CAA

EPA Science Inventory

Life Cycle Impact Analysis (LCIA) has proven to be a valuable tool for systematically comparing processes and products, and has been proposed for use in Chemical Alternatives Analysis (CAA). The exposure assessment portion of the human health impact scores of LCIA has historicall...

Phenothiazine-based CaaX competitive inhibitors of human farnesyltransferase bearing a cysteine, methionine, serine or valine moiety as a new family of antitumoral compounds.

PubMed

Dumitriu, Gina-Mirabela; Bîcu, Elena; Belei, Dalila; Rigo, Benoît; Dubois, Joëlle; Farce, Amaury; Ghinet, Alina

2015-10-15

A new family of CaaX competitive inhibitors of human farnesyltransferase based on phenothiazine and carbazole skeleton bearing a l-cysteine, l-methionine, l-serine or l-valine moiety was designed, synthesized and biologically evaluated. Phenothiazine derivatives proved to be more active than carbazole-based compounds. Phenothiazine 1b with cysteine residue was the most promising inhibitor of human farnesyltransferase in the current study. Copyright © 2015 Elsevier Ltd. All rights reserved.

Data catalog for JPL Physical Oceanography Distributed Active Archive Center (PO.DAAC)

NASA Technical Reports Server (NTRS)

Digby, Susan

1995-01-01

The Physical Oceanography Distributed Active Archive Center (PO.DAAC) archive at the Jet Propulsion Laboratory contains satellite data sets and ancillary in-situ data for the ocean sciences and global-change research to facilitate multidisciplinary use of satellite ocean data. Geophysical parameters available from the archive include sea-surface height, surface-wind vector, surface-wind speed, surface-wind stress vector, sea-surface temperature, atmospheric liquid water, integrated water vapor, phytoplankton pigment concentration, heat flux, and in-situ data. PO.DAAC is an element of the Earth Observing System Data and Information System and is the United States distribution site for TOPEX/POSEIDON data and metadata.

Dominant behaviours in the expression of human carbonic anhydrase hCA I activity.

PubMed

Abdelrahim, M Yahia M; Tanc, Muhammet; Winum, Jean-Yves; Supuran, Claudiu T; Barboiu, Mihail

2014-07-28

Here we describe the screening via Dynamic Deconvolution of DCLs of inhibitors (CAIs) and activators (CAAs) of hCA I. The inhibitory effects dominate over the activating ones, while the CAAs may be identified in the absence of CAIs.

Combined effect of loss of the caa3 oxidase and Crp regulation drives Shewanella to thrive in redox-stratified environments.

PubMed

Zhou, Guangqi; Yin, Jianhua; Chen, Haijiang; Hua, Yijie; Sun, Linlin; Gao, Haichun

2013-09-01

Shewanella species are a group of facultative Gram-negative microorganisms with remarkable respiration abilities that allow the use of a diverse array of terminal electron acceptors (EA). Like most bacteria, S. oneidensis possesses multiple terminal oxidases, including two heme-copper oxidases (caa3- and cbb3-type) and a bd-type quinol oxidase. As aerobic respiration is energetically favored, mechanisms underlying the fact that these microorganisms thrive in redox-stratified environments remain vastly unexplored. In this work, we discovered that the cbb3-type oxidase is the predominant system for respiration of oxygen (O2), especially when O2 is abundant. Under microaerobic conditions, the bd-type quinol oxidase has a significant role in addition to the cbb3-type oxidase. In contrast, multiple lines of evidence suggest that under test conditions the caa3-type oxidase, an analog to the mitochondrial enzyme, has no physiological significance, likely because of its extremely low expression. In addition, expression of both cbb3- and bd-type oxidases is under direct control of Crp (cAMP receptor protein) but not the well-established redox regulator Fnr (fumarate nitrate regulator) of canonical systems typified in Escherichia coli. These data, collectively, suggest that adaptation of S. oneidensis to redox-stratified environments is likely due to functional loss of the caa3-type oxidase and switch of the regulatory system for respiration.

ATXN2 with intermediate-length CAG/CAA repeats does not seem to be a risk factor in hereditary spastic paraplegia.

PubMed

Nielsen, Troels Tolstrup; Svenstrup, Kirsten; Budtz-Jørgensen, Esben; Eiberg, Hans; Hasholt, Lis; Nielsen, Jørgen E

2012-10-15

Hereditary spastic paraplegia (HSP) confines a group of heterogeneous neurodegenerative disorders characterized by progressive spasticity and lower limb weakness. Age of onset is highly variable even in familial cases with known mutations suggesting that the disease is modulated by other yet unknown parameters. Although progressive gait disturbances, lower limb spasticity and extensor plantar responses are hallmarks of HSP these characteristics are also found in other neurodegenerative disorders, e.g. amytrophic lateral sclerosis (ALS). HSP has been linked to ALS and frontotemporal degeneration with motor neuron disease (FTD-MND), since TDP-43 positive inclusions have recently been found in an HSP subtype, and TDP-43 are found in abundance in pathological inclusions of both ALS and FTD-MND. Furthermore, ataxin-2 (encoded by the gene ATXN2), a polyglutamine containing protein elongated in spinocerebellar ataxia type 2, has been shown to be a modulator of TDP-43 induced toxicity in ALS animal and cell models. Finally, it has been shown that ATXN2 with non-pathogenic intermediate-length CAG/CAA repeat elongations (encoding the polyglutamine tract) is a genetic risk factor of ALS. Considering the similarities in the disease phenotype and the neuropathological link between ALS and HSP we hypothesized that intermediate-length CAG/CAA repeats in ATXN2 could be a modulator of HSP. We show that in a cohort of 181 HSP patients 4.9 % of the patients had intermediate-length CAG/CAA repeats in ATXN2 which was not significantly different from the frequencies in a Danish control cohort or in American and European control populations. However, the mean age of onset was significantly lower in HSP patients with intermediate-length CAG/CAA repeats in ATXN2 compared to patients with normal length repeats. Based on these results we conclude that ATXN2 is most likely not a risk factor of HSP, whereas it might serve as a modulator of age of onset. Copyright © 2012 Elsevier B.V. All

40 CFR 51.902 - Which classification and nonattainment area planning provisions of the CAA shall apply to areas...

Code of Federal Regulations, 2011 CFR

2011-07-01

... area planning provisions of the CAA shall apply to areas designated nonattainment for the 8-hour NAAQS? 51.902 Section 51.902 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.902 Which classification and...

40 CFR 51.902 - Which classification and nonattainment area planning provisions of the CAA shall apply to areas...

Code of Federal Regulations, 2014 CFR

2014-07-01

... area planning provisions of the CAA shall apply to areas designated nonattainment for the 1997 8-hour NAAQS? 51.902 Section 51.902 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.902 Which classification and...

40 CFR 51.902 - Which classification and nonattainment area planning provisions of the CAA shall apply to areas...

Code of Federal Regulations, 2012 CFR

2012-07-01

... area planning provisions of the CAA shall apply to areas designated nonattainment for the 1997 8-hour NAAQS? 51.902 Section 51.902 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.902 Which classification and...

40 CFR 51.902 - Which classification and nonattainment area planning provisions of the CAA shall apply to areas...

Code of Federal Regulations, 2013 CFR

2013-07-01

... area planning provisions of the CAA shall apply to areas designated nonattainment for the 1997 8-hour NAAQS? 51.902 Section 51.902 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.902 Which classification and...

40 CFR 51.902 - Which classification and nonattainment area planning provisions of the CAA shall apply to areas...

Code of Federal Regulations, 2010 CFR

2010-07-01

... area planning provisions of the CAA shall apply to areas designated nonattainment for the 8-hour NAAQS? 51.902 Section 51.902 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Implementation of 8-hour Ozone National Ambient Air Quality Standard § 51.902 Which classification and...

Time-resolved single-turnover of caa(3) oxidase from Thermus thermophilus. Fifth electron of the fully reduced enzyme converts O(H) into E(H) state.

PubMed

Siletsky, Sergey A; Belevich, Ilya; Belevich, Nikolai P; Soulimane, Tewfik; Verkhovsky, Michael I

2011-09-01

The oxidative part of the catalytic cycle of the caa(3)-type cytochrome c oxidase from Thermus thermophilus was followed by time-resolved optical spectroscopy. Rate constants, chemical nature and the spectral properties of the catalytic cycle intermediates (Compounds A, P, F) reproduce generally the features typical for the aa(3)-type oxidases with some distinctive peculiarities caused by the presence of an additional 5-th redox-center-a heme center of the covalently bound cytochrome c. Compound A was formed with significantly smaller yield compared to aa(3) oxidases in general and to ba(3) oxidase from the same organism. Two electrons, equilibrated between three input redox-centers: heme a, Cu(A) and heme c are transferred in a single transition to the binuclear center during reduction of the compound F, converting the binuclear center through the highly reactive O(H) state into the final product of the reaction-E(H) (one-electron reduced) state of the catalytic site. In contrast to previous works on the caa(3)-type enzymes, we concluded that the finally produced E(H) state of caa(3) oxidase is characterized by the localization of the fifth electron in the binuclear center, similar to the O(H)→E(H) transition of the aa(3)-type oxidases. So, the fully-reduced caa(3) oxidase is competent in rapid electron transfer from the input redox-centers into the catalytic heme-copper site. 2011 Elsevier B.V. All rights reserved.

The function of the earth observing system - Data information system Distributed Active Archive Centers

NASA Technical Reports Server (NTRS)

Lapenta, C. C.

1992-01-01

The functionality of the Distributed Active Archive Centers (DAACs) which are significant elements of the Earth Observing System Data and Information System (EOSDIS) is discussed. Each DAAC encompasses the information management system, the data archival and distribution system, and the product generation system. The EOSDIS DAACs are expected to improve the access to earth science data set needed for global change research.

Architecture and evolution of Goddard Space Flight Center Distributed Active Archive Center

NASA Technical Reports Server (NTRS)

Bedet, Jean-Jacques; Bodden, Lee; Rosen, Wayne; Sherman, Mark; Pease, Phil

1994-01-01

The Goddard Space Flight Center (GSFC) Distributed Active Archive Center (DAAC) has been developed to enhance Earth Science research by improved access to remote sensor earth science data. Building and operating an archive, even one of a moderate size (a few Terabytes), is a challenging task. One of the critical components of this system is Unitree, the Hierarchical File Storage Management System. Unitree, selected two years ago as the best available solution, requires constant system administrative support. It is not always suitable as an archive and distribution data center, and has moderate performance. The Data Archive and Distribution System (DADS) software developed to monitor, manage, and automate the ingestion, archive, and distribution functions turned out to be more challenging than anticipated. Having the software and tools is not sufficient to succeed. Human interaction within the system must be fully understood to improve efficiency to improve efficiency and ensure that the right tools are developed. One of the lessons learned is that the operability, reliability, and performance aspects should be thoroughly addressed in the initial design. However, the GSFC DAAC has demonstrated that it is capable of distributing over 40 GB per day. A backup system to archive a second copy of all data ingested is under development. This backup system will be used not only for disaster recovery but will also replace the main archive when it is unavailable during maintenance or hardware replacement. The GSFC DAAC has put a strong emphasis on quality at all level of its organization. A Quality team has also been formed to identify quality issues and to propose improvements. The DAAC has conducted numerous tests to benchmark the performance of the system. These tests proved to be extremely useful in identifying bottlenecks and deficiencies in operational procedures.

Importance of low-range CAG expansion and CAA interruption in SCA2 Parkinsonism.

PubMed

Kim, Jong-Min; Hong, Susie; Kim, Gyoung Pyoung; Choi, Yoon Jae; Kim, Yu Kyeong; Park, Sung Sup; Kim, Sang Eun; Jeon, Beom S

2007-10-01

To examine the presence of an ATXN2 mutation in patients with parkinsonism in the Korean population and to find the difference in the ATXN2 mutation between ataxic and parkinsonian phenotypes. Survey. Seoul National University Hospital (a referral center). Patients Patients with Parkinson disease (PD) (n = 468) and the Parkinson variant of multiple system atrophy (MSA-P) (n = 135) who were seen at our Department of Neurology during the past 3 years. CAG expansion in spinocerebellar ataxia type 2 (SCA2) alleles was assessed by polymerase chain reaction amplification and fragment analysis, and its size and interruption were verified by cloning and sequencing. SCA2 was tested also in the family members of the probands. Striatal dopamine transporter (DAT) and D(2) receptor status were evaluated in the probands and their SCA2-positive family members using iodine I 123 [(123)I]-radiolabeled fluoropropyl (FP) 2-carbomethoxy-3-(4-iodophenyl) tropane (CIT) with single-photon emission computed tomography (SPECT) and carbon C 11 [(11)C]-radiolabeled raclopride positron emission tomography (PET). We found 3 patients with apparently sporadic disease with expanded CAG repeats in the ATXN2 locus. Two patients had a PD phenotype. The third patient showed an MSA-P phenotype. The CAG repeats in the ATXN2 locus of the patients were 35/22, 34/22, and 32/22, respectively (range in normal population, 19-27). The size of repeats was lower than the CAG repeats (38-51) in ataxic SCA2 in our population. The sequence of expanded CAG repeats was interrupted by CAA as (CAG)(n)(CAA)(CAG)(8) in all the patients. DNA analyses in 2 families showed 2 asymptomatic carriers in each family. In the patient with the PD phenotype, striatal DAT loss was more severe in the putamen than the caudate, and [(11)C]raclopride PET showed an increased relative putamen-caudate binding ratio. The patient with the MSA-P phenotype had severe DAT loss throughout the striatum. Two of 3 asymptomatic carriers had striatal

Stewardship of NASA's Earth Science Data and Ensuring Long-Term Active Archives

NASA Technical Reports Server (NTRS)

Ramapriyan, Hampapuram K.; Behnke, Jeanne

2016-01-01

Program, NASA has followed an open data policy, with non-discriminatory access to data with no period of exclusive access. NASA has well-established processes for assigning and or accepting datasets into one of 12 Distributed Active Archive Centers (DAACs) that are parts of EOSDIS. EOSDIS has been evolving through several information technology cycles, adapting to hardware and software changes in the commercial sector. NASA is responsible for maintaining Earth science data as long as users are interested in using them for research and applications, which is well beyond the life of the data gathering missions. For science data to remain useful over long periods of time, steps must be taken to preserve: (1) Data bits with no corruption, (2) Discoverability and access, (3) Readability, (4) Understandability, (5) Usability' and (6). Reproducibility of results. NASAs Earth Science data and Information System (ESDIS) Project, along with the 12 EOSDIS Distributed Active Archive Centers (DAACs), has made significant progress in each of these areas over the last decade, and continues to evolve its active archive capabilities. Particular attention is being paid in recent years to ensure that the datasets are published in an easily accessible and citable manner through a unified metadata model, a common metadata repository (CMR), a coherent view through the earthdata.gov website, and assignment of Digital Object Identifiers (DOI) with well-designed landing product information pages.

The Rosetta Science Archive: Status and Plans for Enhancing the Archive Content

NASA Astrophysics Data System (ADS)

Heather, David; Barthelemy, Maud; Besse, Sebastien; Fraga, Diego; Grotheer, Emmanuel; O'Rourke, Laurence; Taylor, Matthew; Vallat, Claire

2017-04-01

On 30 September 2016, Rosetta completed its incredible mission by landing on the surface of Comet 67P/Churyumov-Gerasimenko. Although this marked an end to the spacecraft's active operations, intensive work is still ongoing with instrument teams preparing their final science data deliveries for ingestion into ESA's Planetary Science Archive (PSA). In addition, ESA is establishing contracts with some instrument teams to enhance their data and documentation in an effort to provide the best long-term archive possible for the Rosetta mission. Currently, the majority of teams have delivered all of their data from the nominal mission (end of 2015), and are working on their remaining increments from the 1-year mission extension. The aim is to complete the nominal archiving with data from the complete mission by the end of this year, when a full mission archive review will be held. This review will assess the complete data holdings from Rosetta and ensure that the archive is ready for the long-term. With the resources from the operational mission coming to an end, ESA has established a number of 'enhanced archiving' contracts to ensure that the best possible data are delivered to the archive before instrument teams disband. Updates are focused on key aspects of an instrument's calibration or the production of higher level data / information, and are therefore specific to each instrument's needs. These contracts are currently being kicked off, and will run for various lengths depending upon the activities to be undertaken. The full 'archive enhancement' process will run until September 2019, when the post operations activities for Rosetta will end. Within these contracts, most instrument teams will work on providing a Science User Guide for their data, as well as updating calibrations. Several teams will also be delivering higher level and derived products. For example, the VIRTIS team will be updating both their spectral and geometrical calibrations, and will aim to

The Self-Organized Archive: SPASE, PDS and Archive Cooperatives

NASA Astrophysics Data System (ADS)

King, T. A.; Hughes, J. S.; Roberts, D. A.; Walker, R. J.; Joy, S. P.

2005-05-01

Information systems with high quality metadata enable uses and services which often go beyond the original purpose. There are two types of metadata: annotations which are items that comment on or describe the content of a resource and identification attributes which describe the external properties of the resource itself. For example, annotations may indicate which columns are present in a table of data, whereas an identification attribute would indicate source of the table, such as the observatory, instrument, organization, and data type. When the identification attributes are collected and used as the basis of a search engine, a user can constrain on an attribute, the archive can then self-organize around the constraint, presenting the user with a particular view of the archive. In an archive cooperative where each participating data system or archive may have its own metadata standards, providing a multi-system search engine requires that individual archive metadata be mapped to a broad based standard. To explore how cooperative archives can form a larger self-organized archive we will show how the Space Physics Archive Search and Extract (SPASE) data model will allow different systems to create a cooperative and will use Planetary Data System (PDS) plus existing space physics activities as a demonstration.

Possible reduced penetrance of expansion of 44 to 47 CAG/CAA repeats in the TATA-binding protein gene in spinocerebellar ataxia type 17.

PubMed

Oda, Masaya; Maruyama, Hirofumi; Komure, Osamu; Morino, Hiroyuki; Terasawa, Hideo; Izumi, Yuishin; Imamura, Tohru; Yasuda, Minoru; Ichikawa, Keiji; Ogawa, Masafumi; Matsumoto, Masayasu; Kawakami, Hideshi

2004-02-01

Spinocerebellar ataxia type 17 (SCA17) is an autosomal dominant cerebellar ataxia caused by expansion of CAG/CAA trinucleotide repeats in the TATA-binding protein (TBP) gene. Because the number of triplets in patients with SCA17 in previous studies ranged from 43 to 63, the normal number of trinucleotide units has been considered to be 42 or less. However, some healthy subjects in SCA17 pedigrees carry alleles with the same number of expanded repeats as patients with SCA17. To investigate the minimum number of CAG/CAA repeats in the TBP gene that causes SCA17. We amplified the region of the TBP gene containing the CAG/CAA repeat by means of polymerase chain reaction and performed fragment and sequence analyses. The subjects included 734 patients with SCA (480 patients with sporadic SCA and 254 patients with familial SCA) without CAG repeat expansions at the SCA1, SCA2, Machado-Joseph disease, SCA6, SCA7, or dentatorubral-pallidolluysian atrophy loci, with 162 healthy subjects, 216 patients with Parkinson disease, and 195 with Alzheimer disease as control subjects. Eight patients with SCA possessed an allele with more than 43 CAG/CAA repeats. Among the non-SCA groups, alleles with 43 to 45 repeats were seen in 3 healthy subjects and 2 with Parkinson disease. In 1 SCA pedigree, a patient with possible SCA17 and her healthy sister had alleles with 45 repeats. A 34-year-old man carrying alleles with 47 and 44 repeats (47/44) had developed progressive cerebellar ataxia and myoclonus at 25 years of age, and he exhibited dementia and pyramidal signs. He was the only affected person in his pedigree, although his father and mother carried alleles with mildly expanded repeats (44/36 and 47/36, respectively). In another pedigree, 1 patient carried a 43-repeat allele, whereas another patient had 2 normal alleles, indicating that the 43-repeat allele may not be pathologic in this family. We estimate that 44 CAG/CAA repeats is the minimum number required to cause SCA17. However

Planetary Data Archiving Activities in Indian Space Research Organisation (isro)

NASA Astrophysics Data System (ADS)

Gopala Krishna, Barla; Srivastava, Pradeep Kumar

and related ancillary data. The archive includes raw and reduced data, calibration data, auxiliary data, higher-level derived data products, documentation and software. The ISDA makes use of the well-proven archive standards of the Planetary Data System (PDS) and planning to follow IPDA guidelines. This is to comply with the global standards for long term preservation of the data to maintain the usability and facilitate scientific community with the high quality data for their analysis. The data deliveries from various instruments are already started to ISSDC. The science archives received from MiniSAR and M3 are peer reviewed by the host organizations and hence no further reviews planned at ISSDC. For the other instrument data archives, peer reviews are planned at ISSDC, for which the activity will start during April 2010. A pre review has already been carried out for certain instrument data sets and currently the review comments are being incorporated. The data for the first normal phase operation (November 2008 to February 2009) is planned to be made available (through long term archive) sometime during August 2010 to the users. However the data is already available to the PI teams in the PDS standard, for analysis and use in the instrument cross calibration. Chandrayaan-2 is the next planetary mission to Moon from ISRO in future (which will carry rovers; expected to give a good amount of science data, which is also planned to be archived in ISSDC for dissemination.

Interim report on Landsat national archive activities

NASA Technical Reports Server (NTRS)

Boyd, John E.

1993-01-01

The Department of the Interior (DOI) has the responsibility to preserve and to distribute most Landsat Thematic Mapper (TM) and Multispectral Scanner (MSS) data that have been acquired by the five Landsat satellites operational since July 1972. Data that are still covered by exclusive marketing rights, which were granted by the U.S. Government to the commercial Landsat operator, cannot be distributed by the DOI. As the designated national archive for Landsat data, the U.S. Geological Survey's EROS Data Center (EDC) has initiated two new programs to protect and make available any of the 625,000 MSS scenes currently archived and the 200,000 TM scenes to be archived at EDC by 1995. A specially configured system has begun converting Landsat MSS data from obsolete high density tapes (HDT's) to more dense digital cassette tapes. After transcription, continuous satellite swaths are (1) divided into standard scenes defined by a world reference system, (2) geographically located by latitude and longitude, and (3) assessed for overall quality. Digital browse images are created by subsampling the full-resolution swaths. Conversion of the TM HDT's will begin in the fourth quarter of 1992 and will be conducted concurrently with MSS conversion. Although the TM archive is three times larger than the entire MSS archive, conversion of data from both sensor systems and consolidation of the entire Landsat archive at EDC will be completed by the end of 1994. Some MSS HDT's have deteriorated, primarily as a result of hydrolysis of the pigment binder. Based on a small sample of the 11 terabytes of post-1978 MSS data and the 41 terabytes of TM data to be converted, it appears that to date, less than 2 percent of the data have been lost. The data loss occurs within small portions of some scenes; few scenes are lost entirely. Approximately 10,000 pre-1979 MSS HDT's have deteriorated to such an extent, as a result of hydrolysis, that the data cannot be recovered without special treatment of

Validation of High-Fidelity CFD/CAA Framework for Launch Vehicle Acoustic Environment Simulation against Scale Model Test Data

NASA Technical Reports Server (NTRS)

Liever, Peter A.; West, Jeffrey S.; Harris, Robert E.

2016-01-01

A hybrid Computational Fluid Dynamics and Computational Aero-Acoustics (CFD/CAA) modeling framework has been developed for launch vehicle liftoff acoustic environment predictions. The framework couples the existing highly-scalable NASA production CFD code, Loci/CHEM, with a high-order accurate Discontinuous Galerkin solver developed in the same production framework, Loci/THRUST, to accurately resolve and propagate acoustic physics across the entire launch environment. Time-accurate, Hybrid RANS/LES CFD modeling is applied for predicting the acoustic generation physics at the plume source, and a high-order accurate unstructured mesh Discontinuous Galerkin (DG) method is employed to propagate acoustic waves away from the source across large distances using high-order accurate schemes. The DG solver is capable of solving 2nd, 3rd, and 4th order Euler solutions for non-linear, conservative acoustic field propagation. Initial application testing and validation has been carried out against high resolution acoustic data from the Ares Scale Model Acoustic Test (ASMAT) series to evaluate the capabilities and production readiness of the CFD/CAA system to resolve the observed spectrum of acoustic frequency content. This paper presents results from this validation and outlines efforts to mature and improve the computational simulation framework.

Validation of High-Fidelity CFD/CAA Framework for Launch Vehicle Acoustic Environment Simulation against Scale Model Test Data

NASA Technical Reports Server (NTRS)

Liever, Peter A.; West, Jeffrey S.

2016-01-01

A hybrid Computational Fluid Dynamics and Computational Aero-Acoustics (CFD/CAA) modeling framework has been developed for launch vehicle liftoff acoustic environment predictions. The framework couples the existing highly-scalable NASA production CFD code, Loci/CHEM, with a high-order accurate discontinuous Galerkin solver developed in the same production framework, Loci/THRUST, to accurately resolve and propagate acoustic physics across the entire launch environment. Time-accurate, Hybrid RANS/LES CFD modeling is applied for predicting the acoustic generation physics at the plume source, and a high-order accurate unstructured discontinuous Galerkin (DG) method is employed to propagate acoustic waves away from the source across large distances using high-order accurate schemes. The DG solver is capable of solving 2nd, 3rd, and 4th order Euler solutions for non-linear, conservative acoustic field propagation. Initial application testing and validation has been carried out against high resolution acoustic data from the Ares Scale Model Acoustic Test (ASMAT) series to evaluate the capabilities and production readiness of the CFD/CAA system to resolve the observed spectrum of acoustic frequency content. This paper presents results from this validation and outlines efforts to mature and improve the computational simulation framework.

A historical overview of the development of manganese (Mn) pharmacokinetic data under Section 211(b) of the Clean Air Act (CAA)

EPA Science Inventory

Abstract for Manganese 2016A historical overview of the development of manganese (Mn) pharmacokinetic data under Section 211(b) of the Clean Air Act (CAA)William K BoyesBackground. In the 1990’s, the use of methylcyclopentadienyl manganese tricarbonyl (MMT) as an octane-enh...

JPL Physical Oceanography Distributed Active Archive Center (PO.DAAC) data availability, version 1-94

NASA Technical Reports Server (NTRS)

1994-01-01

The Physical Oceanography Distributed Active Archive Center (PO.DAAC) archive at the Jet Propulsion Laboratory (JPL) includes satellite data sets for the ocean sciences and global-change research to facilitate multidisciplinary use of satellite ocean data. Parameters include sea-surface height, surface-wind vector, sea-surface temperature, atmospheric liquid water, and integrated water vapor. The JPL PO.DAAC is an element of the Earth Observing System Data and Information System (EOSDIS) and is the United States distribution site for Ocean Topography Experiment (TOPEX)/POSEIDON data and metadata.

Building a COTS archive for satellite data

NASA Technical Reports Server (NTRS)

Singer, Ken; Terril, Dave; Kelly, Jack; Nichols, Cathy

1994-01-01

The goal of the NOAA/NESDIS Active Archive was to provide a method of access to an online archive of satellite data. The archive had to manage and store the data, let users interrogate the archive, and allow users to retrieve data from the archive. Practical issues of the system design such as implementation time, cost and operational support were examined in addition to the technical issues. There was a fixed window of opportunity to create an operational system, along with budget and staffing constraints. Therefore, the technical solution had to be designed and implemented subject to constraint imposed by the practical issues. The NOAA/NESDIS Active Archive came online in July of 1994, meeting all of its original objectives.

GHRC: NASAs Hazardous Weather Distributed Active Archive Center

NASA Technical Reports Server (NTRS)

Ramachandran, Rahul; Bugbee, Kaylin

2016-01-01

The Global Hydrology Resource Center (GHRC; ghrc.nsstc.nasa.gov) is one of NASA's twelve Distributed Active Archive Centers responsible for providing access to NASA's Earth science data to users worldwide. Each of NASA's twelve DAACs focuses on a specific science discipline within Earth science, provides data stewardship services and supports its research community's needs. Established in 1991 as the Marshall Space Flight Center DAAC and renamed GHRC in 1997, the data center's original mission focused on the global hydrologic cycle. However, over the years, data holdings, tools and expertise of GHRC have gradually shifted. In 2014, a User Working Group (UWG) was established to review GHRC capabilities and provide recommendations to make GHRC more responsive to the research community's evolving needs. The UWG recommended an update to the GHRC mission, as well as a strategic plan to move in the new direction. After a careful and detailed analysis of GHRC's capabilities, research community needs and the existing data landscape, a new mission statement for GHRC has been crafted: to provide a comprehensive active archive of both data and knowledge augmentation services with a focus on hazardous weather, its governing dynamical and physical processes, and associated applications. Within this broad mandate, GHRC will focus on lightning, tropical cyclones and storm-induced hazards through integrated collections of satellite, airborne, and in-situ data sets. The new mission was adopted at the recent 2015 UWG meeting. GHRC will retain its current name until such time as it has built substantial data holdings aligned with the new mission.

Constraint based scheduling for the Goddard Space Flight Center distributed Active Archive Center's data archive and distribution system

NASA Technical Reports Server (NTRS)

Short, Nick, Jr.; Bedet, Jean-Jacques; Bodden, Lee; Boddy, Mark; White, Jim; Beane, John

1994-01-01

The Goddard Space Flight Center (GSFC) Distributed Active Archive Center (DAAC) has been operational since October 1, 1993. Its mission is to support the Earth Observing System (EOS) by providing rapid access to EOS data and analysis products, and to test Earth Observing System Data and Information System (EOSDIS) design concepts. One of the challenges is to ensure quick and easy retrieval of any data archived within the DAAC's Data Archive and Distributed System (DADS). Over the 15-year life of EOS project, an estimated several Petabytes (10(exp 15)) of data will be permanently stored. Accessing that amount of information is a formidable task that will require innovative approaches. As a precursor of the full EOS system, the GSFC DAAC with a few Terabits of storage, has implemented a prototype of a constraint-based task and resource scheduler to improve the performance of the DADS. This Honeywell Task and Resource Scheduler (HTRS), developed by Honeywell Technology Center in cooperation the Information Science and Technology Branch/935, the Code X Operations Technology Program, and the GSFC DAAC, makes better use of limited resources, prevents backlog of data, provides information about resources bottlenecks and performance characteristics. The prototype which is developed concurrently with the GSFC Version 0 (V0) DADS, models DADS activities such as ingestion and distribution with priority, precedence, resource requirements (disk and network bandwidth) and temporal constraints. HTRS supports schedule updates, insertions, and retrieval of task information via an Application Program Interface (API). The prototype has demonstrated with a few examples, the substantial advantages of using HTRS over scheduling algorithms such as a First In First Out (FIFO) queue. The kernel scheduling engine for HTRS, called Kronos, has been successfully applied to several other domains such as space shuttle mission scheduling, demand flow manufacturing, and avionics communications

A Caco-2 cell-based quantitative antioxidant activity assay for antioxidants.

PubMed

Wan, Hongxia; Liu, Dong; Yu, Xiangying; Sun, Haiyan; Li, Yan

2015-05-15

A Caco-2 cell-based antioxidant activity (CAA) assay for quantitative evaluation of antioxidants was developed by optimizing seeding density and culture time of Caco-2 cells, incubation time and concentration of fluorescent probe (2',7'-dichlorofluorescin diacetate, DCFH-DA), incubation way and incubation time of antioxidants (pure phytochemicals) and DCFH-DA with cells, and detection time of fluorescence. Results showed that the CAA assay was of good reproducibility and could be used to evaluate the antioxidant activity of antioxidants at the following conditions: seeding density of 5 × 10(4)/well, cell culture time of 24h, co-incubation of 60 μM DCFH-DA and pure phytochemicals with Caco-2 cells for 20 min and fluorescence recorded for 90 min. Additionally, a significant correlation was observed between CAA values and rat plasma ORAC values following the intake of antioxidants for selected pure phytochemicals (R(2) = 0.815, p < 0.01), demonstrating the good biological relevance of CAA assay. Copyright © 2014 Elsevier Ltd. All rights reserved.

Trace metal depositional patterns from an open pit mining activity as revealed by archived avian gizzard contents.

PubMed

Bendell, L I

2011-02-15

Archived samples of blue grouse (Dendragapus obscurus) gizzard contents, inclusive of grit, collected yearly between 1959 and 1970 were analyzed for cadmium, lead, zinc, and copper content. Approximately halfway through the 12-year sampling period, an open-pit copper mine began activities, then ceased operations 2 years later. Thus the archived samples provided a unique opportunity to determine if avian gizzard contents, inclusive of grit, could reveal patterns in the anthropogenic deposition of trace metals associated with mining activities. Gizzard concentrations of cadmium and copper strongly coincided with the onset of opening and the closing of the pit mining activity. Gizzard zinc and lead demonstrated significant among year variation; however, maximum concentrations did not correlate to mining activity. The archived gizzard contents did provide a useful tool for documenting trends in metal depositional patterns related to an anthropogenic activity. Further, blue grouse ingesting grit particles during the time of active mining activity would have been exposed to toxicologically significant levels of cadmium. Gizzard lead concentrations were also of toxicological significance but not related to mining activity. This type of "pulse" toxic metal exposure as a consequence of open-pit mining activity would not necessarily have been revealed through a "snap-shot" of soil, plant or avian tissue trace metal analysis post-mining activity. Copyright © 2010 Elsevier B.V. All rights reserved.

Bioenergetics at extreme temperature: Thermus thermophilus ba(3)- and caa(3)-type cytochrome c oxidases.

PubMed

Radzi Noor, Mohamed; Soulimane, Tewfik

2012-04-01

Seven years into the completion of the genome sequencing projects of the thermophilic bacterium Thermus thermophilus strains HB8 and HB27, many questions remain on its bioenergetic mechanisms. A key fact that is occasionally overlooked is that oxygen has a very limited solubility in water at high temperatures. The HB8 strain is a facultative anaerobe whereas its relative HB27 is strictly aerobic. This has been attributed to the absence of nitrate respiration genes from the HB27 genome that are carried on a mobilizable but highly-unstable plasmid. In T. thermophilus, the nitrate respiration complements the primary aerobic respiration. It is widely known that many organisms encode multiple biochemically-redundant components of the respiratory complexes. In this minireview, the presence of the two cytochrome c oxidases (CcO) in T. thermophilus, the ba(3)- and caa(3)-types, is outlined along with functional considerations. We argue for the distinct evolutionary histories of these two CcO including their respective genetic and molecular organizations, with the caa(3)-oxidase subunits having been initially 'fused'. Coupled with sequence analysis, the ba(3)-oxidase crystal structure has provided evolutionary and functional information; for example, its subunit I is more closely related to archaeal sequences than bacterial and the substrate-enzyme interaction is hydrophobic as the elevated growth temperature weakens the electrostatic interactions common in mesophiles. Discussion on the role of cofactors in intra- and intermolecular electron transfer and proton pumping mechanism is also included. Copyright © 2011 Elsevier B.V. All rights reserved.

The Rosetta Science Archive: Status and Plans for Completing and Enhancing the Archive Content

NASA Astrophysics Data System (ADS)

Heather, D.; Barthelemy, M.; Fraga, D.; Grotheer, E.; O'Rourke, L.; Taylor, M.

2017-09-01

On 30 September 2016, Rosetta's signal flat-lined, confirming that the spacecraft had completed its incredible mission by landing on the surface of Comet 67P/Churyumov-Gerasimenko. Although this marked an end to the spacecraft's active operations, intensive work is still on-going with instrument teams preparing their final science data increments for delivery and ingestion into ESA's Planetary Science Archive (PSA). In addition to this, ESA is establishing contracts with a number of instrument teams to enhance and improve their data and documentation in an effort to provide the best long- term archive possible for the Rosetta mission. This presentation will outline the current status of the Rosetta archive, as well as highlighting some of the 'enhanced archiving' activities planned and underway with the various instrument teams on Rosetta to ensure the scientific legacy of the mission.

The NASA Distributed Active Archive Center Experience in Providing Trustworthy Digital Repositories

NASA Astrophysics Data System (ADS)

de Sherbinin, A. M.; Downs, R. R.; Chen, R. S.

2017-12-01

Since the early 1990s, NASA Earth Observation System Data and Information System (EOSDIS) has supported between 10 to 12 discipline-specific Distributed Active Archive Centers (DAACs) that have provided long-term preservation of Earth Science data records, particularly from satellite and airborne remote sensing. The focus of this presentation is on two of the DAACs - the Socioeconomic Data and Applications Center (SEDAC) and Oak Ridge National Laboratory (ORNL) DAAC - that provide archiving and dissemination of third party data sets. The presentation describes the community of interest for these two DAACs, their data management practices, and the benefits of certification to the DAACs and their user communities. It also describes the organizational, technical, financial, and legal challenges to providing trustworthy long-term data stewardship.

Building A Cloud Based Distributed Active Data Archive Center

NASA Technical Reports Server (NTRS)

Ramachandran, Rahul; Baynes, Katie; Murphy, Kevin

2017-01-01

NASA's Earth Science Data System (ESDS) Program facilitates the implementation of NASA's Earth Science strategic plan, which is committed to the full and open sharing of Earth science data obtained from NASA instruments to all users. The Earth Science Data information System (ESDIS) project manages the Earth Observing System Data and Information System (EOSDIS). Data within EOSDIS are held at Distributed Active Archive Centers (DAACs). One of the key responsibilities of the ESDS Program is to continuously evolve the entire data and information system to maximize returns on the collected NASA data.

Stewardship of NASA's Earth Science Data and Ensuring Long-Term Active Archives

NASA Astrophysics Data System (ADS)

Ramapriyan, H.; Behnke, J.

2016-12-01

NASA's Earth Observing System Data and Information System (EOSDIS) has been in operation since 1994. EOSDIS manages data from pre-EOS missions dating back to 1960s, EOS missions that started in 1997, and missions from the post-EOS era. Its data holdings come from many different sources - satellite and airborne instruments, in situ measures, field experiments, science investigations, etc. Since the beginning of the EOS Program, NASA has followed an open data policy, with non-discriminatory access to data with no period of exclusive access. NASA has well-established processes for assigning and/or accepting datasets into one of 12 Distributed Active Archive Centers (DAACs) that are parts of EOSDIS. EOSDIS has been evolving through several information technology cycles, adapting to hardware and software changes in the commercial sector. NASA is responsible for maintaining Earth science data as long as users are interested in using them for research and applications, which is well beyond the life of the data gathering missions. For science data to remain useful over long periods of time, steps must be taken to preserve: 1. Data bits with no corruption, 2. Discoverability and access, 3. Readability, 4. Understandability, 5. Usability and 6. Reproducibility of results. NASA's Earth Science data and Information System (ESDIS) Project, along with the 12 EOSDIS Distributed Active Archive Centers (DAACs), has made significant progress in each of these areas over the last decade, and continues to evolve its active archive capabilities. Particular attention is being paid in recent years to ensure that the datasets are "published" in an easily accessible and citable manner through a unified metadata model, a common metadata repository (CMR), a coherent view through the earthdata.gov website, and assignment of Digital Object Identifiers (DOI) with well-designed landing/product information pages.

Earth Science Data Archive and Access at the NASA/Goddard Space Flight Center Distributed Active Archive Center (DAAC)

NASA Technical Reports Server (NTRS)

Leptoukh, Gregory

1999-01-01

The Goddard Distributed Active Archive Center (DAAC), as an integral part of the Earth Observing System Data and Information System (EOSDIS), is the official source of data for several important earth remote sensing missions. These include the Sea-viewing Wide-Field-of-view Sensor (SeaWiFS) launched in August 1997, the Tropical Rainfall Measuring Mission (TRMM) launched in November 1997, and the Moderate Resolution Imaging Spectroradiometer (MODIS) scheduled for launch in mid 1999 as part of the EOS AM-1 instrumentation package. The data generated from these missions supports a host of users in the hydrological, land biosphere and oceanographic research and applications communities. The volume and nature of the data present unique challenges to an Earth science data archive and distribution system such as the DAAC. The DAAC system receives, archives and distributes a large number of standard data products on a daily basis, including data files that have been reprocessed with updated calibration data or improved analytical algorithms. A World Wide Web interface is provided allowing interactive data selection and automatic data subscriptions as distribution options. The DAAC also creates customized and value-added data products, which allow additional user flexibility and reduced data volume. Another significant part of our overall mission is to provide ancillary data support services and archive support for worldwide field campaigns designed to validate the results from the various satellite-derived measurements. In addition to direct data services, accompanying documentation, WWW links to related resources, support for EOSDIS data formats, and informed response to inquiries are routinely provided to users. The current GDAAC WWW search and order system is being restructured to provide users with a simplified, hierarchical access to data. Data Browsers have been developed for several data sets to aid users in ordering data. These Browsers allow users to specify

RNA editing in the anticodon of tRNA Leu (CAA) occurs before group I intron splicing in plastids of a moss Takakia lepidozioides S. Hatt. & Inoue.

PubMed

Miyata, Y; Sugita, C; Maruyama, K; Sugita, M

2008-03-01

RNA editing of cytidine (C) to uridine (U) transitions occurs in plastids and mitochondria of most land plants. In this study, we amplified and sequenced the group I intron-containing tRNA Leu gene, trnL-CAA, from Takakia lepidozioides, a moss. DNA sequence analysis revealed that the T. lepidozioides tRNA Leu gene consisted of a 35-bp 5' exon, a 469-bp group I intron and a 50-bp 3' exon. The intron was inserted between the first and second position of the tRNA Leu anticodon. In general, plastid tRNA Leu genes with a group I intron code for a TAA anticodon in most land plants. This strongly suggests that the first nucleotide of the CAA anticodon could be edited in T. lepidozioides plastids. To investigate this possibility, we analysed cDNAs derived from the trnL-CAA transcripts. We demonstrated that the first nucleotide C of the anticodon was edited to create a canonical UAA anticodon in T. lepidozioides plastids. cDNA sequencing analyses of the spliced or unspliced tRNA Leu transcripts revealed that, while the spliced tRNA was completely edited, editing in the unspliced tRNAs were only partial. This is the first experimental evidence that the anticodon editing of tRNA occurs before RNA splicing in plastids. This suggests that this editing is a prerequisite to splicing of pre-tRNA Leu.

Development of a multiplex allele-specific primer PCR assay for simultaneous detection of QoI and CAA fungicide resistance alleles in Plasmopara viticola populations.

PubMed

Aoki, Yoshinao; Hada, Yosuke; Suzuki, Shunji

2013-02-01

DNA-based diagnosis has become a common tool for the evaluation of fungicide resistance in obligate phytopathogenic fungus Plasmopara viticola. A multiplex allele-specific primer PCR assay has been developed for the rapid detection of fungicide resistance in P. viticola populations. With this assay, a glycine-to-alanine substitution at codon 143 of the P. viticola cytochrome b gene, which conferred QoI fungicide resistance, and a glycine-to-serine substitution at codon 1105 of the P. viticola cellulose synthase gene PvCesA3, which conferred CAA fungicide resistance, were detected simultaneously. It is suggested that the present assay is a reliable tool for the rapid and simultaneous detection of QoI and CAA fungicide resistance alleles in P. viticola populations. The assay required only 2 h from the sampling of symptoms to the detection of resistance alleles to both fungicides. Copyright © 2012 Society of Chemical Industry.

Measures of Effectiveness-CONUS Reorganization 1973 (As Pertains to FORSCOM, TRADOC, HSC, OTEA and CAA). Volume I. Executive Summary

DTIC Science & Technology

1974-11-01

obvioun that they were’ dkep]y corncented a d halrd at work in &,tvrloping meaw to masure their rmT effectiveness . This proposed eval- tiatiot plIn wilt be...AD/A-002 532 MEASURES OF EFFECTIVENESS -CONUS REORCAN- IZATION 1973 (AS PERTAINS TO FORSCOM. TRADOC, HSC, OTEA AND CAA). VOLUME I.EXECUTIVE SUMMARY M...resulting Interaction organizational objective goal effectiveness imovati ye chanuge vrasurement are a The study provider, an evaluatinn plan, "ased

The NASA Heliophysics Active Final Archive at the Space Physics Data Facility

NASA Technical Reports Server (NTRS)

McGuire, Robert E.

2012-01-01

The 2009 NASA Heliophysics Science Data Management Policy re-defined and extended the responsibilities of the Space Physics Data Facility (SPDF) project. Building on SPDF's established capabilities, the new policy assigned the role of active "Final Archive" for non-solar NASA Heliophysics data to SPDF. The policy also recognized and formalized the responsibilities of SPDF as a source for critical infrastructure services such as VSPO to the overall Heliophysics Data Environment (HpDE) and as a Center of Excellence for existing SPDF science-enabling services and software including CDAWeb, SSCWeb/4D Orbit Viewer, OMNIweb and CDF. We will focus this talk to the principles, strategies and planned SPDF architecture to effectively and efficiently perform these roles, with special emphasis on how SPDF will ensure the long-term preservation and ongoing online community access to all the data entrusted to SPDF. We will layout our archival philosophy and what we are advocating in our work with NASA missions both current and future, with potential providers of NASA and NASA-relevant archival data, and to make the data and metadata held by SPDF accessible to other systems and services within the overall HpOE. We will also briefly review our current services, their metrics and our current plans and priorities for their evolution.

Design of cinnamaldehyde amino acid Schiff base compounds based on the quantitative structure–activity relationship

Treesearch

Hui Wang; Mingyue Jiang; Shujun Li; Chung-Yun Hse; Chunde Jin; Fangli Sun; Zhuo Li

2017-01-01

Cinnamaldehyde amino acid Schiff base (CAAS) is a new class of safe, bioactive compounds which could be developed as potential antifungal agents for fungal infections. To design new cinnamaldehyde amino acid Schiff base compounds with high bioactivity, the quantitative structure–activity relationships (QSARs) for CAAS compounds against Aspergillus niger (A. niger) and...

The EOSDIS Version 0 Distributed Active Archive Center for physical oceanography and air-sea interaction

NASA Technical Reports Server (NTRS)

Hilland, Jeffrey E.; Collins, Donald J.; Nichols, David A.

1991-01-01

The Distributed Active Archive Center (DAAC) at the Jet Propulsion Laboratory will support scientists specializing in physical oceanography and air-sea interaction. As part of the NASA Earth Observing System Data and Information System Version 0 the DAAC will build on existing capabilities to provide services for data product generation, archiving, distribution and management of information about data. To meet scientist's immediate needs for data, existing data sets from missions such as Seasat, Geosat, the NOAA series of satellites and the Global Positioning Satellite system will be distributed to investigators upon request. In 1992, ocean topography, wave and surface roughness data from the Topex/Poseidon radar altimeter mission will be archived and distributed. New data products will be derived from Topex/Poseidon and other sensor systems based on recommendations of the science community. In 1995, ocean wind field measurements from the NASA Scatterometer will be supported by the DAAC.

Renal cytochrome P450 omega-hydroxylase and epoxygenase activity are differentially modified by nitric oxide and sodium chloride.

PubMed

Oyekan, A O; Youseff, T; Fulton, D; Quilley, J; McGiff, J C

1999-10-01

Renal function is perturbed by inhibition of nitric oxide synthase (NOS). To probe the basis of this effect, we characterized the effects of nitric oxide (NO), a known suppressor of cytochrome P450 (CYP) enzymes, on metabolism of arachidonic acid (AA), the expression of omega-hydroxylase, and the efflux of 20-hydroxyeicosatetraenoic acid (20-HETE) from the isolated kidney. The capacity to convert [(14)C]AA to HETEs and epoxides (EETs) was greater in cortical microsomes than in medullary microsomes. Sodium nitroprusside (10-100 microM), an NO donor, inhibited renal microsomal conversion of [(14)C]AA to HETEs and EETs in a dose-dependent manner. 8-bromo cGMP (100 microM), the cell-permeable analogue of cGMP, did not affect conversion of [(14)C]AA. Inhibition of NOS with N(omega)-nitro-L-arginine-methyl ester (L-NAME) significantly increased conversion of [(14)C]AA to HETE and greatly increased the expression of omega-hydroxylase protein, but this treatment had only a modest effect on epoxygenase activity. L-NAME induced a 4-fold increase in renal efflux of 20-HETE, as did L-nitroarginine. Oral treatment with 2% sodium chloride (NaCl) for 7 days increased renal epoxygenase activity, both in the cortex and the medulla. In contrast, cortical omega-hydroxylase activity was reduced by treatment with 2% NaCl. Coadministration of L-NAME and 2% NaCl decreased conversion of [(14)C]AA to HETEs without affecting epoxygenase activity. Thus, inhibition of NOS increased omega-hydroxylase activity, CYP4A expression, and renal efflux of 20-HETE, whereas 2% NaCl stimulated epoxygenase activity.

Levels of H-ras codon 61 CAA to AAA mutation: response to 4-ABP-treatment and Pms2-deficiency.

PubMed

Parsons, Barbara L; Delongchamp, Robert R; Beland, Frederick A; Heflich, Robert H

2006-01-01

DNA mismatch repair (MMR) deficiencies result in increased frequencies of spontaneous mutation and tumor formation. In the present study, we tested the hypothesis that a chemically-induced mutational response would be greater in a mouse with an MMR-deficiency than in the MMR-proficient mouse models commonly used to assay for chemical carcinogenicity. To accomplish this, the induction of H-ras codon 61 CAA-->AAA mutation was examined in Pms2 knockout mice (Pms2-/-, C57BL/6 background) and sibling wild-type mice (Pms2+/+). Groups of five or six neonatal male mice were treated with 0.3 micromol 4-aminobiphenyl (4-ABP) or the vehicle control, dimethylsulfoxide. Eight months after treatment, liver DNAs were isolated and analysed for levels of H-ras codon 61 CAA-->AAA mutation using allele-specific competitive blocker-PCR. In Pms2-proficient and Pms2-deficient mice, 4-ABP treatment caused an increase in mutant fraction (MF) from 1.65x10(-5) to 2.91x10(-5) and from 3.40x10(-5) to 4.70x10(-5), respectively. Pooling data from 4-ABP-treated and control mice, the approximately 2-fold increase in MF observed in Pms2-deficient as compared with Pms2-proficient mice was statistically significant (P=0.0207) and consistent with what has been reported previously in terms of induction of G:C-->T:A mutation in a Pms2-deficient background. Pooling data from both genotypes, the increase in H-ras MF in 4-ABP-treated mice, as compared with control mice, did not reach the 95% confidence level of statistical significance (P=0.0606). The 4-ABP treatment caused a 1.76-fold and 1.38-fold increase in average H-ras MF in Pms2-proficient and Pms2-deficient mice, respectively. Furthermore, the levels of induced mutation in Pms2-proficient and Pms2-deficient mice were nearly identical (1.26x10(-5) and 1.30x10(-5), respectively). We conclude that Pms2-deficiency does not result in an amplification of the H-ras codon 61 CAA-->AAA mutational response induced by 4-ABP.

Dynamic Data Management Based on Archival Process Integration at the Centre for Environmental Data Archival

NASA Astrophysics Data System (ADS)

Conway, Esther; Waterfall, Alison; Pepler, Sam; Newey, Charles

2015-04-01

In this paper we decribe a business process modelling approach to the integration of exisiting archival activities. We provide a high level overview of existing practice and discuss how procedures can be extended and supported through the description of preservation state. The aim of which is to faciliate the dynamic controlled management of scientific data through its lifecycle. The main types of archival processes considered are: • Management processes that govern the operation of an archive. These management processes include archival governance (preservation state management, selection of archival candidates and strategic management) . • Operational processes that constitute the core activities of the archive which maintain the value of research assets. These operational processes are the acquisition, ingestion, deletion, generation of metadata and preservation actvities, • Supporting processes, which include planning, risk analysis and monitoring of the community/preservation environment. We then proceed by describing the feasability testing of extended risk management and planning procedures which integrate current practices. This was done through the CEDA Archival Format Audit which inspected British Atmospherics Data Centre and National Earth Observation Data Centre Archival holdings. These holdings are extensive, comprising of around 2PB of data and 137 million individual files which were analysed and characterised in terms of format based risk. We are then able to present an overview of the risk burden faced by a large scale archive attempting to maintain the usability of heterogeneous environmental data sets. We conclude by presenting a dynamic data management information model that is capable of describing the preservation state of archival holdings throughout the data lifecycle. We provide discussion of the following core model entities and their relationships: • Aspirational entities, which include Data Entity definitions and their associated

Development of Secondary Archive System at Goddard Space Flight Center Version 0 Distributed Active Archive Center

NASA Technical Reports Server (NTRS)

Sherman, Mark; Kodis, John; Bedet, Jean-Jacques; Wacker, Chris; Woytek, Joanne; Lynnes, Chris

1996-01-01

The Goddard Space Flight Center (GSFC) version 0 Distributed Active Archive Center (DAAC) has been developed to support existing and pre Earth Observing System (EOS) Earth science datasets, facilitate the scientific research, and test EOS data and information system (EOSDIS) concepts. To ensure that no data is ever lost, each product received at GSFC DAAC is archived on two different media, VHS and digital linear tape (DLT). The first copy is made on VHS tape and is under the control of UniTree. The second and third copies are made to DLT and VHS media under a custom built software package named 'Archer'. While Archer provides only a subset of the functions available with commercial software like UniTree, it supports migration between near-line and off-line media and offers much greater performance and flexibility to satisfy the specific needs of a data center. Archer is specifically designed to maximize total system throughput, rather than focusing on the turn-around time for individual files. The commercial off the shelf software (COTS) hierarchical storage management (HSM) products evaluated were mainly concerned with transparent, interactive, file access to the end-user, rather than a batch-orientated, optimizable (based on known data file characteristics) data archive and retrieval system. This is critical to the distribution requirements of the GSFC DAAC where orders for 5000 or more files at a time are received. Archer has the ability to queue many thousands of file requests and to sort these requests into internal processing schedules that optimize overall throughput. Specifically, mount and dismount, tape load and unload cycles, and tape motion are minimized. This feature did not seem to be available in many COTS pacages. Archer also uses a generic tar tape format that allows tapes to be read by many different systems rather than the proprietary format found in most COTS packages. This paper discusses some of the specific requirements at GSFC DAAC, the

Ifosfamide metabolites CAA, 4-OH-Ifo and Ifo-mustard reduce apical phosphate transport by changing NaPi-IIa in OK cells.

PubMed

Patzer, L; Hernando, N; Ziegler, U; Beck-Schimmer, B; Biber, J; Murer, H

2006-11-01

Renal Fanconi syndrome occurs in about 1-5% of all children treated with Ifosfamide (Ifo) and impairment of renal phosphate reabsorption in about 20-30% of them. Pathophysiological mechanisms of Ifo-induced nephropathy are ill defined. The aim has been to investigate whether Ifo metabolites affect the type IIa sodium-dependent phosphate transporter (NaPi-IIa) in viable opossum kidney cells. Ifo did not influence viability of cells or NaPi-IIa-mediated transport up to 1 mM/24 h. Incubation of confluent cells with chloroacetaldehyde (CAA) and 4-hydroperoxyIfosfamide (4-OH-Ifo) led to cell death by necrosis in a concentration-dependent manner. At low concentrations (50-100 microM/24 h), cell viability was normal but apical phosphate transport, NaPi-IIa protein, and -mRNA expression were significantly reduced. Coincubation with sodium-2-mercaptoethanesulfonate (MESNA) prevented the inhibitory action of CAA but not of 4-OH-Ifo; DiMESNA had no effect. Incubation with Ifosfamide-mustard (Ifo-mustard) did alter cell viability at concentrations above 500 microM/24 h. At lower concentrations (50-100 microM/24 h), it led to significant reduction in phosphate transport, NaPi-IIa protein, and mRNA expression. MESNA did not block these effects. The effect of Ifo-mustard was due to internalization of NaPi-IIa. Cyclophosphamide-mustard (CyP-mustard) did not have any influence on cell survival up to 1000 microM, but the inhibitory effect on phosphate transport and on NaPi-IIa protein was the same as found after Ifo-mustard. In conclusion, CAA, 4-OH-Ifo, and Ifo- and CyP-mustard are able to inhibit sodium-dependent phosphate cotransport in viable opossum kidney cells. The Ifo-mustard effect took place via internalization and reduction of de novo synthesis of NaPi-IIa. Therefore, it is possible that Ifo-mustard plays an important role in pathogenesis of Ifo-induced nephropathy.

HotGAS: A Public Archive of Ready-to-Go Chandra High Energy Grating Spectral Products for Active Galactic Nuclei

NASA Astrophysics Data System (ADS)

Yaqoob, T.

2005-12-01

We describe a public WWW archive (HotGAS) containing data products from Chandra observations using the High Energy Grating Spectrometer (HETGS). Spectral products are available from the archive in various formats and are suitable for use by non-experts and experts alike. Lightcurves and cross-dispersion profiles are also available. Easy and user-friendly access for non X-ray astronomers to reprocessed, publishable quality grating data products should help to promote inter-disciplinary and multi-wavelength research on active galactic nuclei (AGN). The archive will also be useful to X-ray astronomers who have not yet had experience with high resolution X-ray spectroscopy, as well as experienced X-ray astronomers who need quick access to clean and ready-to-go data products. Theoreticians may find the archive useful for testing their models without having to deal with the fine details of data processing and reduction. We also anticipate that the archive will be useful for training graduate students in high-resolution X-ray spectroscopy and for providing a resource for projects for high-school and graduate students. We plan to eventually expand the archive to include AGN data from the Chandra Low Energy Grating Spectrometer (LETGS), and the XMM-Newton Reflection-Grating Spectrometer (RGS). Further in the future we plan to extend the archive to include data from other astrophysical sources aside from AGN. The project thus far is funded by an archival Chandra grant.

Near-line Archive Data Mining at the Goddard Distributed Active Archive Center

NASA Astrophysics Data System (ADS)

Pham, L.; Mack, R.; Eng, E.; Lynnes, C.

2002-12-01

NASA's Earth Observing System (EOS) is generating immense volumes of data, in some cases too much to provide to users with data-intensive needs. As an alternative to moving the data to the user and his/her research algorithms, we are providing a means to move the algorithms to the data. The Near-line Archive Data Mining (NADM) system is the Goddard Earth Sciences Distributed Active Archive Center's (GES DAAC) web data mining portal to the EOS Data and Information System (EOSDIS) data pool, a 50-TB online disk cache. The NADM web portal enables registered users to submit and execute data mining algorithm codes on the data in the EOSDIS data pool. A web interface allows the user to access the NADM system. The users first develops personalized data mining code on their home platform and then uploads them to the NADM system. The C, FORTRAN and IDL languages are currently supported. The user developed code is automatically audited for any potential security problems before it is installed within the NADM system and made available to the user. Once the code has been installed the user is provided a test environment where he/she can test the execution of the software against data sets of the user's choosing. When the user is satisfied with the results, he/she can promote their code to the "operational" environment. From here the user can interactively run his/her code on the data available in the EOSDIS data pool. The user can also set up a processing subscription. The subscription will automatically process new data as it becomes available in the EOSDIS data pool. The generated mined data products are then made available for FTP pickup. The NADM system uses the GES DAAC-developed Simple Scalable Script-based Science Processor (S4P) to automate tasks and perform the actual data processing. Users will also have the option of selecting a DAAC-provided data mining algorithm and using it to process the data of their choice.

Detection of Hb Constant Spring [α142, Term→Gln, TAA>CAA (α2)] in heterozygotes combined with β-thalassemia.

PubMed

Li, You-Qiong; Li, Ru; Li, Dong-Zhi

2013-01-01

Hb Constant Spring [Hb CS, α142, Term→Gln, TAA>CAA (α2)] is a nondeletional form of α-thalassemia (α-thal) that is most prevalent in Southern Chinese and Southeast Asian populations. We previously found that Hb CS trait could efficiently be screened using Sebia Capillarys2. In this study, we report that Hb CS heterozygotes combined with β-thal could not be detected by the Sebia Capillarys2 method due to the very small amount of Hb CS.

Analysis of the access patterns at GSFC distributed active archive center

NASA Technical Reports Server (NTRS)

Johnson, Theodore; Bedet, Jean-Jacques

1996-01-01

The Goddard Space Flight Center (GSFC) Distributed Active Archive Center (DAAC) has been operational for more than two years. Its mission is to support existing and pre Earth Observing System (EOS) Earth science datasets, facilitate the scientific research, and test Earth Observing System Data and Information System (EOSDIS) concepts. Over 550,000 files and documents have been archived, and more than six Terabytes have been distributed to the scientific community. Information about user request and file access patterns, and their impact on system loading, is needed to optimize current operations and to plan for future archives. To facilitate the management of daily activities, the GSFC DAAC has developed a data base system to track correspondence, requests, ingestion and distribution. In addition, several log files which record transactions on Unitree are maintained and periodically examined. This study identifies some of the users' requests and file access patterns at the GSFC DAAC during 1995. The analysis is limited to the subset of orders for which the data files are under the control of the Hierarchical Storage Management (HSM) Unitree. The results show that most of the data volume ordered was for two data products. The volume was also mostly made up of level 3 and 4 data and most of the volume was distributed on 8 mm and 4 mm tapes. In addition, most of the volume ordered was for deliveries in North America although there was a significant world-wide use. There was a wide range of request sizes in terms of volume and number of files ordered. On an average 78.6 files were ordered per request. Using the data managed by Unitree, several caching algorithms have been evaluated for both hit rate and the overhead ('cost') associated with the movement of data from near-line devices to disks. The algorithm called LRU/2 bin was found to be the best for this workload, but the STbin algorithm also worked well.

The Gaia Archive at ESAC: a VO-inside archive

NASA Astrophysics Data System (ADS)

Gonzalez-Nunez, J.

2015-12-01

The ESDC (ESAC Science Data Center) is one of the active members of the IVOA (International Virtual Observatory Alliance) that have defined a set of standards, libraries and concepts that allows to create flexible,scalable and interoperable architectures on the data archives development. In the case of astronomy science that involves the use of big catalogues, as in Gaia or Euclid, TAP, UWS and VOSpace standards can be used to create an architecture that allows the explotation of this valuable data from the community. Also, new challenges arise like the implementation of the new paradigm "move code close to the data", what can be partially obtained by the extension of the protocols (TAP+, UWS+, etc) or the languages (ADQL). We explain how we have used VO standards and libraries for the Gaia Archive that, not only have producing an open and interoperable archive but, also, minimizing the developement on certain areas. Also we will explain how we have extended these protocols and the future plans.

Activating Archives in Women's Studies 101: New Stories about Old Feminism and the Future

ERIC Educational Resources Information Center

McDaneld, Jen

2017-01-01

The classroom is a sort of ground zero for feminist storytelling--it's there that we encounter the commonplace, surface stories students have absorbed about feminism, and it's there that we complicate, reiterate, or replace those stories through our syllabi and coursework. How can activating feminist archives in the classroom intervene in these…

Supporting users through integrated retrieval, processing, and distribution systems at the Land Processes Distributed Active Archive Center

USGS Publications Warehouse

Kalvelage, Thomas A.; Willems, Jennifer

2005-01-01

The US Geological Survey's EROS Data Center (EDC) hosts the Land Processes Distributed Active Archive Center (LP DAAC). The LP DAAC supports NASA's Earth Observing System (EOS), which is a series of polar-orbiting and low inclination satellites for long-term global observations of the land surface, biosphere, solid Earth, atmosphere, and oceans. The EOS Data and Information Systems (EOSDIS) was designed to acquire, archive, manage and distribute Earth observation data to the broadest possible user community.The LP DAAC is one of four DAACs that utilize the EOSDIS Core System (ECS) to manage and archive their data. Since the ECS was originally designed, significant changes have taken place in technology, user expectations, and user requirements. Therefore the LP DAAC has implemented additional systems to meet the evolving needs of scientific users, tailored to an integrated working environment. These systems provide a wide variety of services to improve data access and to enhance data usability through subsampling, reformatting, and reprojection. These systems also support the wide breadth of products that are handled by the LP DAAC.The LP DAAC is the primary archive for the Landsat 7 Enhanced Thematic Mapper Plus (ETM+) data; it is the only facility in the United States that archives, processes, and distributes data from the Advanced Spaceborne Thermal Emission/Reflection Radiometer (ASTER) on NASA's Terra spacecraft; and it is responsible for the archive and distribution of “land products” generated from data acquired by the Moderate Resolution Imaging Spectroradiometer (MODIS) on NASA's Terra and Aqua satellites.

The fifth electron in the fully reduced caa(3) from Thermus thermophilus is competent in proton pumping.

PubMed

Siletsky, Sergey A; Belevich, Ilya; Soulimane, Tewfik; Verkhovsky, Michael I; Wikström, Mårten

2013-01-01

The time-resolved kinetics of membrane potential generation coupled to oxidation of the fully reduced (five-electron) caa(3) cytochrome oxidase from Thermus thermophilus by oxygen was studied in a single-turnover regime. In order to calibrate the number of charges that move across the vesicle membrane in the different reaction steps, the reverse electron transfer from heme a(3) to heme a and further to the cytochrome c/Cu(A) has been resolved upon photodissociation of CO from the mixed valence enzyme in the absence of oxygen. The reverse electron transfer from heme a(3) to heme a and further to the cytochrome c/Cu(A) pair is resolved as a single transition with τ~40 μs. In the reaction of the fully reduced cytochrome caa(3) with oxygen, the first electrogenic phase (τ~30 μs) is linked to OO bond cleavage and generation of the P(R) state. The next electrogenic component (τ~50 μs) is associated with the P(R)→F transition and together with the previous reaction step it is coupled to translocation of about two charges across the membrane. The three subsequent electrogenic phases, with time constants of ~0.25 ms, ~1.4 ms and ~4 ms, are linked to the conversion of the binuclear center through the F→O(H)→E(H) transitions, and result in additional transfer of four charges through the membrane dielectric. This indicates that the delivery of the fifth electron from heme c to the binuclear center is coupled to pumping of an additional proton across the membrane. Copyright © 2012 Elsevier B.V. All rights reserved.

Characterization of the complete mitochondrial genome of the Grey-backed Shrike, Lanius tephronotus (Aves: Passeriformes): the first representative of the family Laniidae with a novel CAA stop codon at the end of cox2 gene.

PubMed

Qian, Chaoju; Yan, Xia; Guo, Zhichun; Wang, Yuanxiu; Li, Xixi; Yang, Jianke; Kan, Xianzhao

2013-08-01

The complete Grey-backed Shrike mitochondrial genome has been sequenced to be 16,820 bp in length, consisting of 37 encode genes: 13 protein-coding genes, 2 ribosomal RNA genes, and 22 transfer RNA genes. In addition, a single control region was also observed. Compared with other reported Passeriformes mtgenome sequences, three bases CAA were detected at the end of Lanius tephronotus cox2 gene with the downstream adjacent base T. The first base of CAA probably occurred C to U transcript editing event resulting in a normal stop codon UAA.

Continuous, Large-Scale Processing of Seismic Archives for High-Resolution Monitoring of Seismic Activity and Seismogenic Properties

NASA Astrophysics Data System (ADS)

Waldhauser, F.; Schaff, D. P.

2012-12-01

Archives of digital seismic data recorded by seismometer networks around the world have grown tremendously over the last several decades helped by the deployment of seismic stations and their continued operation within the framework of monitoring earthquake activity and verification of the Nuclear Test-Ban Treaty. We show results from our continuing effort in developing efficient waveform cross-correlation and double-difference analysis methods for the large-scale processing of regional and global seismic archives to improve existing earthquake parameter estimates, detect seismic events with magnitudes below current detection thresholds, and improve real-time monitoring procedures. We demonstrate the performance of these algorithms as applied to the 28-year long seismic archive of the Northern California Seismic Network. The tools enable the computation of periodic updates of a high-resolution earthquake catalog of currently over 500,000 earthquakes using simultaneous double-difference inversions, achieving up to three orders of magnitude resolution improvement over existing hypocenter locations. This catalog, together with associated metadata, form the underlying relational database for a real-time double-difference scheme, DDRT, which rapidly computes high-precision correlation times and hypocenter locations of new events with respect to the background archive (http://ddrt.ldeo.columbia.edu). The DDRT system facilitates near-real-time seismicity analysis, including the ability to search at an unprecedented resolution for spatio-temporal changes in seismogenic properties. In areas with continuously recording stations, we show that a detector built around a scaled cross-correlation function can lower the detection threshold by one magnitude unit compared to the STA/LTA based detector employed at the network. This leads to increased event density, which in turn pushes the resolution capability of our location algorithms. On a global scale, we are currently building

Archiving of HEAO-1 data products and the creation of a general user's guide to the archive

NASA Technical Reports Server (NTRS)

Nousek, John A.

1993-01-01

The activities at Penn State University are described. Initiated at Penn State in Jan. 1989, the goal of this program was to preserve the results of the HEAO-1 mission by transforming the obsolete and disorganized data products into modern and documented forms. The result of this effort was an archive of top level data products, totalling 70 Mbytes; a general User's Guide to the archive, which is attached; and a hardcopy archive containing standardized plots and output of fits made to all the pointing data taken by the HEAO-1 A-2 LED experiment. A more detailed description of these activities is found in the following sections. Accompanying this document is a copy of the User's Guide which may provide additional detail.

Getting Personal: Personal Archives in Archival Programs and Curricula

ERIC Educational Resources Information Center

Douglas, Jennifer

2017-01-01

In 2001, Catherine Hobbs referred to silences around personal archives, suggesting that these types of archives were not given as much attention as organizational archives in the development of archival theory and methodology. The aims of this article are twofold: 1) to investigate the extent to which such silences exist in archival education…

A comprehensive cost model for NASA data archiving

NASA Technical Reports Server (NTRS)

Green, J. L.; Klenk, K. F.; Treinish, L. A.

1990-01-01

A simple archive cost model has been developed to help predict NASA's archiving costs. The model covers data management activities from the beginning of the mission through launch, acquisition, and support of retrospective users by the long-term archive; it is capable of determining the life cycle costs for archived data depending on how the data need to be managed to meet user requirements. The model, which currently contains 48 equations with a menu-driven user interface, is available for use on an IBM PC or AT.

Real-time data archiving for GTA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, R.A.; Atkins, W.H.

1992-09-01

The architecture of the GTA control system, the nature of a typical GTA commissioning activity, and the varied interests of those analyzing the data make it challenging to develop a general-purpose scheme for archiving data and making the data available to those who will use it. Addressing the needs of those who develop and trouble-shoot hardware and software increases the challenge. This paper describes the aspects of GTA that affect archiving operations and discusses how the features of the EPICS archiving module meet a variety of needs for storing and accessing data.

Real-time data archiving for GTA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, R.A.; Atkins, W.H.

1992-01-01

The architecture of the GTA control system, the nature of a typical GTA commissioning activity, and the varied interests of those analyzing the data make it challenging to develop a general-purpose scheme for archiving data and making the data available to those who will use it. Addressing the needs of those who develop and trouble-shoot hardware and software increases the challenge. This paper describes the aspects of GTA that affect archiving operations and discusses how the features of the EPICS archiving module meet a variety of needs for storing and accessing data.

Crew Activity Analyzer

NASA Technical Reports Server (NTRS)

Murray, James; Kirillov, Alexander

2008-01-01

The crew activity analyzer (CAA) is a system of electronic hardware and software for automatically identifying patterns of group activity among crew members working together in an office, cockpit, workshop, laboratory, or other enclosed space. The CAA synchronously records multiple streams of data from digital video cameras, wireless microphones, and position sensors, then plays back and processes the data to identify activity patterns specified by human analysts. The processing greatly reduces the amount of time that the analysts must spend in examining large amounts of data, enabling the analysts to concentrate on subsets of data that represent activities of interest. The CAA has potential for use in a variety of governmental and commercial applications, including planning for crews for future long space flights, designing facilities wherein humans must work in proximity for long times, improving crew training and measuring crew performance in military settings, human-factors and safety assessment, development of team procedures, and behavioral and ethnographic research. The data-acquisition hardware of the CAA (see figure) includes two video cameras: an overhead one aimed upward at a paraboloidal mirror on the ceiling and one mounted on a wall aimed in a downward slant toward the crew area. As many as four wireless microphones can be worn by crew members. The audio signals received from the microphones are digitized, then compressed in preparation for storage. Approximate locations of as many as four crew members are measured by use of a Cricket indoor location system. [The Cricket indoor location system includes ultrasonic/radio beacon and listener units. A Cricket beacon (in this case, worn by a crew member) simultaneously transmits a pulse of ultrasound and a radio signal that contains identifying information. Each Cricket listener unit measures the difference between the times of reception of the ultrasound and radio signals from an identified beacon

Structural insights into electron transfer in caa3-type cytochrome oxidase

PubMed Central

Lyons, Joseph A.; Aragão, David; Slattery, Orla; Pisliakov, Andrei V.; Soulimane, Tewfik; Caffrey, Martin

2012-01-01

Summary Paragraph Cytochrome c oxidase is a member of the heme copper oxidase superfamily (HCO)1. HCOs function as the terminal enzymes in the respiratory chain of mitochondria and aerobic prokaryotes, coupling molecular oxygen reduction to transmembrane proton pumping. Integral to the enzyme’s function is the transfer of electrons from cytochrome c to the oxidase via a transient association of the two proteins. Electron entry and exit are proposed to occur from the same site on cytochrome c2–4. Here we report the crystal structure of the caa3-type cytochrome oxidase from Thermus thermophilus, which has a covalently tethered cytochrome c domain. Crystals were grown in a bicontinuous mesophase using a synthetic short-chain monoacylglycerol as the hosting lipid. From the electron density map, at 2.36 Å resolution, a novel integral membrane subunit and a native glycoglycerophospholipid embedded in the complex were identified. Contrary to previous electron transfer mechanisms observed for soluble cytochrome c, the structure reveals the architecture of the electron transfer complex for the fused cupredoxin/cytochrome c domain which implicates different sites on cytochrome c for electron entry and exit. Support for an alternative to the classical proton gate characteristic of this HCO class is presented. PMID:22763450

State Implementation Plans; General Preamble & Lead (Pb) Addendum for the Implementation of Title I of the Clean Air Act (CAA) Amendments of 1990 (57 FR 13498 & 58 FR 67748)

EPA Pesticide Factsheets

This page contains a copy of the 1993 & 1993 Federal Register publications of the State Implementation Plans (SIPs); General Preamble & Lead (Pb) Addendum for the Implementation of Title I of the Clean Air Act (CAA) Amendments of 1990.

Enlivening Dance History Pedagogy through Archival Projects

ERIC Educational Resources Information Center

Randall, Tresa

2012-01-01

Dance archives can bring students into contact with historical subjects through artifacts of the past. This article advocates the use of archival projects in undergraduate dance history courses, arguing that such hands-on learning activities give students dynamic and interactive experiences of history. The author describes a creative project she…

TxDOT ITS data archiving research project activities

DOT National Transportation Integrated Search

2001-09-01

The objective of this project was to assemble guidance for the Texas Department of Trasportation (TxDOT) in further developing data archiving systems across the state. This guidance, which is contained in the companion Report 2127-3, includes informa...

The Nation's Memory: The United States National Archives and Records Administration. An Interview with Don W. Wilson, Archivist of the United States, National Archives and Records Administration.

ERIC Educational Resources Information Center

Brodhead, Michael J.; Zink, Steven D.

1993-01-01

Discusses the National Archives and Records Administration (NARA) through an interview with the Archivist of the United States, Don Wilson. Topics addressed include archival independence and congressional relations; national information policy; expansion plans; machine-readable archival records; preservation activities; and relations with other…

The Kanzelhöhe Online Data Archive

NASA Astrophysics Data System (ADS)

Pötzi, W.; Hirtenfellner-Polanec, W.; Temmer, M.

The Kanzelhöhe Observatory provides high-cadence full-disk observations of solar activity phenomena like sunspots, flares and prominence eruptions on a regular basis. The data are available for download from the KODA (Kanzelhöhe Observatory Data Archive) which is freely accessible. The archive offers sunspot drawings back to 1950 and high cadence H-α data back to 1973. Images from other instruments, like white-light and CaIIK, are available since 2007 and 2010, respectively. In the following we describe how to access the archive and the format of the data.

Study of Stevia rebaudiana Bertoni antioxidant activities and cellular properties.

PubMed

Bender, Cecilia; Graziano, Sara; Zimmermann, Benno F

2015-01-01

The aim of our study was to determine the antioxidant activities, cytotoxicity and proliferative properties in Stevia rebaudiana leaves and stems. Leaves extracts exhibited a higher antioxidant activity than stems extract, through oxygen radical absorbance capacity (ORAC) and cellular antioxidant activity (CAA) assays. Stevioside and rebaudioside A, the main sweetening metabolites in stevia leaves, exhibited a low ORAC value in comparison with plant extracts, while did not elicit any CAA. Stevia rebaudiana did not exhibit toxicity against HepG2 (hepatocellular carcinoma) human cells. No proliferative nor catalase modulations were observed in cells treated with such extracts. Our findings support the promising role of stevia that, apart from its sweetness, can act as a source of antioxidants, even at the intracellular level. This activity makes S. rebaudiana crude extract an interesting resource of natural sweetness with antioxidant properties which may find numerous applications in foods and nutritional supplements industries.

Archive interoperability in the Virtual Observatory

NASA Astrophysics Data System (ADS)

Genova, Françoise

2003-02-01

Main goals of Virtual Observatory projects are to build interoperability between astronomical on-line services, observatory archives, databases and results published in journals, and to develop tools permitting the best scientific usage from the very large data sets stored in observatory archives and produced by large surveys. The different Virtual Observatory projects collaborate to define common exchange standards, which are the key for a truly International Virtual Observatory: for instance their first common milestone has been a standard allowing exchange of tabular data, called VOTable. The Interoperability Work Area of the European Astrophysical Virtual Observatory project aims at networking European archives, by building a prototype using the CDS VizieR and Aladin tools, and at defining basic rules to help archive providers in interoperability implementation. The prototype is accessible for scientific usage, to get user feedback (and science results!) at an early stage of the project. ISO archive participates very actively to this endeavour, and more generally to information networking. The on-going inclusion of the ISO log in SIMBAD will allow higher level links for users.

Gaia archive

NASA Astrophysics Data System (ADS)

Hypki, Arkadiusz; Brown, Anthony

2016-06-01

The Gaia archive is being designed and implemented by the DPAC Consortium. The purpose of the archive is to maximize the scientific exploitation of the Gaia data by the astronomical community. Thus, it is crucial to gather and discuss with the community the features of the Gaia archive as much as possible. It is especially important from the point of view of the GENIUS project to gather the feedback and potential use cases for the archive. This paper presents very briefly the general ideas behind the Gaia archive and presents which tools are already provided to the community.

Evolution of Archival Storage (from Tape to Memory)

NASA Technical Reports Server (NTRS)

Ramapriyan, Hampapuram K.

2015-01-01

Over the last three decades, there has been a significant evolution in storage technologies supporting archival of remote sensing data. This section provides a brief survey of how these technologies have evolved. Three main technologies are considered - tape, hard disk and solid state disk. Their historical evolution is traced, summarizing how reductions in cost have helped being able to store larger volumes of data on faster media. The cost per GB of media is only one of the considerations in determining the best approach to archival storage. Active archives generally require faster response to user requests for data than permanent archives. The archive costs have to consider facilities and other capital costs, operations costs, software licenses, utilities costs, etc. For meeting requirements in any organization, typically a mix of technologies is needed.

Opening the Landsat Archive

USGS Publications Warehouse

,

2008-01-01

The USGS Landsat archive holds an unequaled 36-year record of the Earth's surface that is invaluable to climate change studies, forest and resource management activities, and emergency response operations. An aggressive effort is taking place to provide all Landsat imagery [scenes currently held in the USGS Earth Resources Observation and Science (EROS) Center archive, as well as newly acquired scenes daily] free of charge to users with electronic access via the Web by the end of December 2008. The entire Landsat 7 Enhanced Thematic Mapper Plus (ETM+) archive acquired since 1999 and any newly acquired Landsat 7 ETM+ images that have less than 40 percent cloud cover are currently available for download. When this endeavor is complete all Landsat 1-5 data will also be available for download. This includes Landsat 1-5 Multispectral Scanner (MSS) scenes, as well as Landsat 4 and 5 Thematic Mapper (TM) scenes.

The Operation and Architecture of the Keck Observatory Archive

NASA Astrophysics Data System (ADS)

Berriman, G. B.; Gelino, C. R.; Laity, A.; Kong, M.; Swain, M.; Holt, J.; Goodrich, R.; Mader, J.; Tran, H. D.

2014-05-01

The Infrared Processing and Analysis Center (IPAC) and the W. M. Keck Observatory (WMKO) are collaborating to build an archive for the twin 10-m Keck Telescopes, located near the summit of Mauna Kea. The Keck Observatory Archive (KOA) takes advantage of IPAC's long experience with managing and archiving large and complex data sets from active missions and serving them to the community; and of the Observatory's knowledge of the operation of its sophisticated instrumentation and the organization of the data products. By the end of 2013, KOA will contain data from all eight active observatory instruments, with an anticipated volume of 28 TB. The data include raw science and observations, quick look products, weather information, and, for some instruments, reduced and calibrated products. The goal of including data from all instruments is the cumulation of a rapid expansion of the archive's holdings, and already data from four new instruments have been added since October 2012. One more active instrument, the integral field spectrograph OSIRIS, is scheduled for ingestion in December 2013. After preparation for ingestion into the archive, the data are transmitted electronically from WMKO to IPAC for curation in the physical archive. This process includes validation of the science and content of the data and verification that data were not corrupted in transmission. The archived data include both newly-acquired observations and all previously acquired observations. The older data extends back to the date of instrument commissioning; for some instruments, such as HIRES, these data can extend as far back as 1994. KOA will continue to ingest all newly obtained observations, at an anticipated volume of 4 TB per year, and plans to ingest data from two decommissioned instruments. Access to these data is governed by a data use policy that guarantees Principal Investigators (PI) exclusive access to their data for at least 18 months, and allows for extensions as granted by

AVIRIS and TIMS data processing and distribution at the land processes distributed active archive center

NASA Technical Reports Server (NTRS)

Mah, G. R.; Myers, J.

1993-01-01

The U.S. Government has initiated the Global Change Research program, a systematic study of the Earth as a complete system. NASA's contribution of the Global Change Research Program is the Earth Observing System (EOS), a series of orbital sensor platforms and an associated data processing and distribution system. The EOS Data and Information System (EOSDIS) is the archiving, production, and distribution system for data collected by the EOS space segment and uses a multilayer architecture for processing, archiving, and distributing EOS data. The first layer consists of the spacecraft ground stations and processing facilities that receive the raw data from the orbiting platforms and then separate the data by individual sensors. The second layer consists of Distributed Active Archive Centers (DAAC) that process, distribute, and archive the sensor data. The third layer consists of a user science processing network. The EOSDIS is being developed in a phased implementation. The initial phase, Version 0, is a prototype of the operational system. Version 0 activities are based upon existing systems and are designed to provide an EOSDIS-like capability for information management and distribution. An important science support task is the creation of simulated data sets for EOS instruments from precursor aircraft or satellite data. The Land Processes DAAC, at the EROS Data Center (EDC), is responsible for archiving and processing EOS precursor data from airborne instruments such as the Thermal Infrared Multispectral Scanner (TIMS), the Thematic Mapper Simulator (TMS), and Airborne Visible and Infrared Imaging Spectrometer (AVIRIS). AVIRIS, TIMS, and TMS are flown by the NASA-Ames Research Center ARC) on an ER-2. The ER-2 flies at 65000 feet and can carry up to three sensors simultaneously. Most jointly collected data sets are somewhat boresighted and roughly registered. The instrument data are being used to construct data sets that simulate the spectral and spatial

Design of cinnamaldehyde amino acid Schiff base compounds based on the quantitative structure-activity relationship.

PubMed

Wang, Hui; Jiang, Mingyue; Li, Shujun; Hse, Chung-Yun; Jin, Chunde; Sun, Fangli; Li, Zhuo

2017-09-01

Cinnamaldehyde amino acid Schiff base (CAAS) is a new class of safe, bioactive compounds which could be developed as potential antifungal agents for fungal infections. To design new cinnamaldehyde amino acid Schiff base compounds with high bioactivity, the quantitative structure-activity relationships (QSARs) for CAAS compounds against Aspergillus niger ( A. niger ) and Penicillium citrinum (P. citrinum) were analysed. The QSAR models ( R 2  = 0.9346 for A. niger , R 2  = 0.9590 for P. citrinum, ) were constructed and validated. The models indicated that the molecular polarity and the Max atomic orbital electronic population had a significant effect on antifungal activity. Based on the best QSAR models, two new compounds were designed and synthesized. Antifungal activity tests proved that both of them have great bioactivity against the selected fungi.

Design of cinnamaldehyde amino acid Schiff base compounds based on the quantitative structure–activity relationship

PubMed Central

Wang, Hui; Jiang, Mingyue; Hse, Chung-Yun; Jin, Chunde; Sun, Fangli; Li, Zhuo

2017-01-01

Cinnamaldehyde amino acid Schiff base (CAAS) is a new class of safe, bioactive compounds which could be developed as potential antifungal agents for fungal infections. To design new cinnamaldehyde amino acid Schiff base compounds with high bioactivity, the quantitative structure–activity relationships (QSARs) for CAAS compounds against Aspergillus niger (A. niger) and Penicillium citrinum (P. citrinum) were analysed. The QSAR models (R2 = 0.9346 for A. niger, R2 = 0.9590 for P. citrinum,) were constructed and validated. The models indicated that the molecular polarity and the Max atomic orbital electronic population had a significant effect on antifungal activity. Based on the best QSAR models, two new compounds were designed and synthesized. Antifungal activity tests proved that both of them have great bioactivity against the selected fungi. PMID:28989758

Archival Services and Technologies for Scientific Data

NASA Astrophysics Data System (ADS)

Meyer, Jörg; Hardt, Marcus; Streit, Achim; van Wezel, Jos

2014-06-01

After analysis and publication, there is no need to keep experimental data online on spinning disks. For reliability and costs inactive data is moved to tape and put into a data archive. The data archive must provide reliable access for at least ten years following a recommendation of the German Science Foundation (DFG), but many scientific communities wish to keep data available much longer. Data archival is on the one hand purely a bit preservation activity in order to ensure the bits read are the same as those written years before. On the other hand enough information must be archived to be able to use and interpret the content of the data. The latter is depending on many also community specific factors and remains an areas of much debate among archival specialists. The paper describes the current practice of archival and bit preservation in use for different science communities at KIT for which a combination of organizational services and technical tools are required. The special monitoring to detect tape related errors, the software infrastructure in use as well as the service certification are discussed. Plans and developments at KIT also in the context of the Large Scale Data Management and Analysis (LSDMA) project are presented. The technical advantages of the T10 SCSI Stream Commands (SSC-4) and the Linear Tape File System (LTFS) will have a profound impact on future long term archival of large data sets.

Pesticide Active Ingredient Production Industry: National Emission Standards for Hazardous Air Pollutants (NESHAP)

EPA Pesticide Factsheets

This action promulgates national emission standards for hazardous air pollutants (NESHAP) for the pesticide active ingredient (PAI) production source category under section 112 of the Clean Air Act as amended (CAA or Act).

Enabling data access and interoperability at the EOS Land Processes Distributed Active Archive Center

NASA Astrophysics Data System (ADS)

Meyer, D. J.; Gallo, K. P.

2009-12-01

The NASA Earth Observation System (EOS) is a long-term, interdisciplinary research mission to study global-scale processes that drive Earth systems. This includes a comprehensive data and information system to provide Earth science researchers with easy, affordable, and reliable access to the EOS and other Earth science data through the EOS Data and Information System (EOSDIS). Data products from EOS and other NASA Earth science missions are stored at Distributed Active Archive Centers (DAACs) to support interactive and interoperable retrieval and distribution of data products. ¶ The Land Processes DAAC (LP DAAC), located at the US Geological Survey’s (USGS) Earth Resources Observation and Science (EROS) Center is one of the twelve EOSDIS data centers, providing both Earth science data and expertise, as well as a mechanism for interaction between EOS data investigators, data center specialists, and other EOS-related researchers. The primary mission of the LP DAAC is stewardship for land data products from the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) and the Moderate Resolution Imaging Spectroradiometer (MODIS) instruments on the Terra and Aqua observation platforms. The co-location of the LP DAAC at EROS strengthens the relationship between the EOSDIS and USGS Earth science activities, linking the basic research and technology development mission of NASA to the operational mission requirements of the USGS. This linkage, along with the USGS’ role as steward of land science data such as the Landsat archive, will prove to be especially beneficial when extending both USGS and EOSDIS data records into the Decadal Survey era. ¶ This presentation provides an overview of the evolution of LP DAAC efforts over the years to improve data discovery, retrieval and preparation services, toward a future of integrated data interoperability between EOSDIS data centers and data holdings of the USGS and its partner agencies. Historical developmental

The ISO Data Archive and Interoperability with Other Archives

NASA Astrophysics Data System (ADS)

Salama, Alberto; Arviset, Christophe; Hernández, José; Dowson, John; Osuna, Pedro

The ESA's Infrared Space Observatory (ISO), an unprecedented observatory for infrared astronomy launched in November 1995, successfully made nearly 30,000 scientific observations in its 2.5-year mission. The ISO data can be retrieved from the ISO Data Archive, available at ISO Data Archive , and comprised of about 150,000 observations, including parallel and serendipity mode observations. A user-friendly Java interface permits queries to the database and data retrieval. The interface currently offers a wide variety of links to other archives, such as name resolution with NED and SIMBAD, access to electronic articles from ADS and CDS/VizieR, and access to IRAS data. In the past year development has been focused on improving the IDA interoperability with other astronomical archives, either by accessing other relevant archives or by providing direct access to the ISO data for external services. A mechanism of information transfer has been developed, allowing direct query to the IDA via a Java Server Page, returning quick look ISO images and relevant, observation-specific information embedded in an HTML page. This method has been used to link from the CDS/Vizier Data Centre and ADS, and work with IPAC to allow access to the ISO Archive from IRSA, including display capabilities of the observed sky regions onto other mission images, is in progress. Prospects for further links to and from other archives and databases are also addressed.

The Planetary Archive

NASA Astrophysics Data System (ADS)

Penteado, Paulo F.; Trilling, David; Szalay, Alexander; Budavári, Tamás; Fuentes, César

2014-11-01

We are building the first system that will allow efficient data mining in the astronomical archives for observations of Solar System Bodies. While the Virtual Observatory has enabled data-intensive research making use of large collections of observations across multiple archives, Planetary Science has largely been denied this opportunity: most astronomical data services are built based on sky positions, and moving objects are often filtered out.To identify serendipitous observations of Solar System objects, we ingest the archive metadata. The coverage of each image in an archive is a volume in a 3D space (RA,Dec,time), which we can represent efficiently through a hierarchical triangular mesh (HTM) for the spatial dimensions, plus a contiguous time interval. In this space, an asteroid occupies a curve, which we determine integrating its orbit into the past. Thus when an asteroid trajectory intercepts the volume of an archived image, we have a possible observation of that body. Our pipeline then looks in the archive's catalog for a source with the corresponding coordinates, to retrieve its photometry. All these matches are stored into a database, which can be queried by object identifier.This database consists of archived observations of known Solar System objects. This means that it grows not only from the ingestion of new images, but also from the growth in the number of known objects. As new bodies are discovered, our pipeline can find archived observations where they could have been recorded, providing colors for these newly-found objects. This growth becomes more relevant with the new generation of wide-field surveys, particularly LSST.We also present one use case of our prototype archive: after ingesting the metadata for SDSS, 2MASS and GALEX, we were able to identify serendipitous observations of Solar System bodies in these 3 archives. Cross-matching these occurrences provided us with colors from the UV to the IR, a much wider spectral range than that

Self-assembling cyclic tetrapeptide from alternating C-linked carbo-beta-amino acid [(S)-beta-Caa] and alpha-aminoxy acid [(R)-Ama]: a selective chloride ion receptor.

PubMed

Sharma, Gangavaram V M; Manohar, Vennampalli; Dutta, Samit Kumar; Sridhar, Bojja; Ramesh, Venna; Srinivas, Ragampeta; Kunwar, Ajit C

2010-02-19

A cyclic tetrapeptide is prepared from alternating (S)-beta-Caa (C-linked carbo-beta-amino acid) and (R)-Ama (alpha-aminoxy acid). Extensive NMR (in CDCl(3) solution) and mass spectral (MS) studies show its halide binding capacity, with a special affinity to the chloride ion. At higher concentration it was found to form molecular aggregates as evidenced from transmission electron microscopic and atomic force microscopic analysis, confirming the formation of nanorods.

Dang An: A Brief History of the Chinese Imperial Archives and Its Administration

ERIC Educational Resources Information Center

Zhang, Wenxian

2004-01-01

Archives are preserved records of human activities. An account of Chinese archival development is as long as the written records of the Chinese history. Oracle bones, bronze ware, and wood and bamboo strips are the three most important recording forms of the early Chinese civilization, as they represented three major stages of archival development…

Significance of different carbon forms and carbonic anhydrase activity in monitoring and prediction of algal blooms in the urban section of Jialing River, Chongqing, China.

PubMed

Nie, Yudong; Zhang, Zhi; Shen, Qian; Gao, Wenjin; Li, Yingfan

2016-05-18

The Three Gorges Dam is one of the largest hydroelectric power plants worldwide; its reservoir was preliminarily impounded in 2003 and finally impounded to 175 m in 2012. The impoundment caused some environmental problems, such as algal blooms. Carbonic anhydrase (CA) is an important biocatalyst in the carbon utilization by algae and plays an important role in algal blooms. CA has received considerable attention for its role in red tides in oceans, but less investigation has been focused on its role in algal blooms in fresh water. In this study, the seasonal variation of water quality parameters, different carbon forms, carbonic anhydrase activity (CAA), and the algal cell density of four sampling sites in the urban section of the Jialing River were investigated from November 1, 2013 to October 31, 2014. Results indicated that CAA exhibited a positive correlation with dissoluble organic carbon (DOC), pH, and temperature, but a negative correlation with CO2 and dissoluble inorganic carbon (DIC). Algal cell density exhibited a positive correlation with flow velocity (V), pH, particulate organic carbon (POC), and CAA, a negative correlation with CO2, and a negative partial correlation with DIC. The relationship between CAA and algal cell density for the entire year can be described as cells = 23.278CAA - 42.666POC + 139.547pH - 1057.106. The algal bloom prediction model for the key control period can be described as cells = -45.895CAA + 776.103V- 29.523DOC + 14.219PIC + 35.060POC + 19.181 (2 weeks in advance) and cells = 69.200CAA + 203.213V + 4.184CO2 + 38.911DOC + 40.770POC - 189.567 (4 weeks in advance). The findings in this study demonstrate that the carbon utilization by algae is conducted by CA and provide a new method of monitoring algal cell density and predicting algal blooms.

CDDIS: NASA's Archive of Space Geodesy Data and Products Supporting GGOS

NASA Technical Reports Server (NTRS)

Noll, Carey; Michael, Patrick

2016-01-01

The Crustal Dynamics Data Information System (CDDIS) supports data archiving and distribution activities for the space geodesy and geodynamics community. The main objectives of the system are to store space geodesy and geodynamics related data and products in a central archive, to maintain information about the archival of these data,to disseminate these data and information in a timely manner to a global scientific research community, and provide user based tools for the exploration and use of the archive. The CDDIS data system and its archive is a key component in several of the geometric services within the International Association of Geodesy (IAG) and its observing systemthe Global Geodetic Observing System (GGOS), including the IGS, the International DORIS Service (IDS), the International Laser Ranging Service (ILRS), the International VLBI Service for Geodesy and Astrometry (IVS), and the International Earth Rotation and Reference Systems Service (IERS). The CDDIS provides on-line access to over 17 Tbytes of dataand derived products in support of the IAG services and GGOS. The systems archive continues to grow and improve as new activities are supported and enhancements are implemented. Recently, the CDDIS has established a real-time streaming capability for GNSS data and products. Furthermore, enhancements to metadata describing the contents ofthe archive have been developed to facilitate data discovery. This poster will provide a review of the improvements in the system infrastructure that CDDIS has made over the past year for the geodetic community and describe future plans for the system.

VLBA Archive &Distribution Architecture

NASA Astrophysics Data System (ADS)

Wells, D. C.

1994-01-01

Signals from the 10 antennas of NRAO's VLBA [Very Long Baseline Array] are processed by a Correlator. The complex fringe visibilities produced by the Correlator are archived on magnetic cartridges using a low-cost architecture which is capable of scaling and evolving. Archive files are copied to magnetic media to be distributed to users in FITS format, using the BINTABLE extension. Archive files are labelled using SQL INSERT statements, in order to bind the DBMS-based archive catalog to the archive media.

A Robust, Low-Cost Virtual Archive for Science Data

NASA Technical Reports Server (NTRS)

Lynnes, Christopher; Vollmer, Bruce

2005-01-01

Despite their expense tape silos are still often the only affordable option for petabytescale science data archives, particularly when other factors such as data reliability, floor space, power and cooling load are accounted for. However, the complexity, management software, hardware reliability and access latency of tape silos make online data storage ever more attractive. Drastic reductions in low-cost mass-market PC disk drivers help to make this more affordable (approx. 1$/GB), but are challenging to scale to the petabyte range and of questionable reliability for archival use, On the other hand, if much of the science archive could be "virtualized", i.e., produced on demand when requested by users, we would need store only a fraction of the data online, perhaps bringing an online-only system into in affordable range. Radiance data from the satellite-borne Moderate Resolution Imaging Spectroradiometer (MODIS) instrument provides a good opportunity for such a virtual archive: the raw data amount to 140 GB/day, but these are small relative to the 550 GB/day making up the radiance products. These data are routinely processed as inputs for geophysical parameter products and then archived on tape at the Goddard Earth Sciences Distributed Active Archive (GES DAAC) for distributing to users. Virtualizing them would be an immediate and signifcant reduction in the amount of data being stored in the tape archives and provide more customizable products. A prototype of such a virtual archive is being developed to prove the concept and develop ways of incorporating the robustness that a science data archive requires.

Theoretical and experimental studies on alpha/epsilon-hybrid peptides: design of a 14/12-helix from peptides with alternating (S)-C-linked carbo-epsilon-amino acid [(S)-epsilon-Caa((x))] and L-ala.

PubMed

Sharma, Gangavaram V M; Babu, Bommagani Shoban; Chatterjee, Deepak; Ramakrishna, Kallaganti V S; Kunwar, Ajit C; Schramm, Peter; Hofmann, Hans-Jörg

2009-09-04

An (S)-C-linked carbo-epsilon-amino acid [(S)-epsilon-Caa((x))] was prepared from the known (S)-delta-Caa. This monomer was utilized together with l-Ala to give novel alpha/epsilon-hybrid peptides in 1:1 alternation. Conformational analysis on penta- and hexapeptides by NMR (in CDCl(3)), CD, and MD studies led to the identification of robust 14/12-mixed helices. This is in agreement with the data from a theoretical conformational analysis on the basis of ab initio MO theory providing a complete overview on all formally possible hydrogen-bonded helix patterns of alpha/epsilon-hybrid peptides with 1:1 backbone alternation. The "new motif" of a mixed 14/12-helix was predicted as most stable in vacuum. Obviously, the formation of ordered secondary structures is also possible in peptide foldamers with amino acid constituents of considerable backbone lengths. Thus, alpha/epsilon-hybrid peptides expand the domain of foldamers and allow the introduction of desired functionalities via the alpha-amino acid constituents.

Technology and the Transformation of Archival Description

ERIC Educational Resources Information Center

Pitti, Daniel V.

2005-01-01

The emergence of computer and network technologies has presented the archival profession with daunting challenges as well as inspiring opportunities. Archivists have been actively imagining and realizing the application of advanced technologies to their professional functions and activities. Using advanced technologies, archivists have been…

My Dream Archive

ERIC Educational Resources Information Center

Phelps, Christopher

2007-01-01

In this article, the author shares his experience as he traveled from island to island with a single objective--to reach the archives. He found out that not all archives are the same. In recent months, his daydreaming in various facilities has yielded a recurrent question on what would constitute the Ideal Archive. What follows, in no particular…

Phytochemical profiles and antioxidant activity of 27 cultivars of tea.

PubMed

Zeng, Liang; Luo, Liyong; Li, Hongjun; Liu, Ruihai

2017-08-01

Tea, rich in phytochemicals, has been suggested to have human health benefits. The phenolic profiles, antioxidant and antiproliferative activities of 27 tea cultivars were determined. Wide ranges of variation were found in analyzed cultivars for the contents of water-soluble phenolics (121.6-223.7 mg/g dry weight (DW)), total catechins (TC) (90.5-177.2 mg/g DW), antioxidant activities (PSC values 627.3-2332.3 μmol of vitamin C equiv/g DW, ORAC values (1865.1-3489.3 μmol of vitamin C equiv/g DW), CAA values (37.7-134.3 μmol of QE/g DW without PBS wash and 25.3-75.4 μmol of QE/g DW with PBS wash) and antiproliferative activity (53.0-90.8% at the concentration of 400 μg/mL extracts). The PSC, ORAC and CAA values were significantly correlated with phenolics, epicatechin gallate (ECG), CC and TC. Knowledge of specific differences among tea cultivars is important for breeding tea cultivars and gives sights to its potential application to promote health.

Operational environmental satellite archives in the 21st Century

NASA Astrophysics Data System (ADS)

Barkstrom, Bruce R.; Bates, John J.; Privette, Jeff; Vizbulis, Rick

2007-09-01

NASA, NOAA, and USGS collections of Earth science data are large, federated, and have active user communities and collections. Our experience raises five categories of issues for long-term archival: *Organization of the data in the collections is not well-described by text-based categorization principles *Metadata organization for these data is not well-described by Dublin Core and needs attention to data access and data use patterns *Long-term archival requires risk management approaches to dealing with the unique threats to knowledge preservation specific to digital information *Long-term archival requires careful attention to archival cost management *Professional data stewards for these collections may require special training. This paper suggests three mechanisms for improving the quality of long-term archival: *Using a maturity model to assess the readiness of data for accession, for preservation, and for future data usefulness *Developing a risk management strategy for systematically dealing with threats of data loss *Developing a life-cycle cost model for continuously evolving the collections and the data centers that house them.

Trends and variability in summer sea ice cover in the Canadian Arctic based on the Canadian Ice Service Digital Archive, 1960-2008 and 1968-2008

NASA Astrophysics Data System (ADS)

Tivy, Adrienne; Howell, Stephen E. L.; Alt, Bea; McCourt, Steve; Chagnon, Richard; Crocker, Greg; Carrieres, Tom; Yackel, John J.

2011-03-01

The Canadian Ice Service Digital Archive (CISDA) is a compilation of weekly ice charts covering Canadian waters from the early 1960s to present. The main sources of uncertainty in the database are reviewed and the data are validated for use in climate studies before trends and variability in summer averaged sea ice cover are investigated. These data revealed that between 1968 and 2008, summer sea ice cover has decreased by 11.3% ± 2.6% decade-1 in Hudson Bay, 2.9% ± 1.2% decade-1 in the Canadian Arctic Archipelago (CAA), 8.9% ± 3.1% decade-1 in Baffin Bay, and 5.2% ± 2.4% decade-1 in the Beaufort Sea with no significant reductions in multiyear ice. Reductions in sea ice cover are linked to increases in early summer surface air temperature (SAT); significant increases in SAT were observed in every season and they are consistently greater than the pan-Arctic change by up to ˜0.2°C decade-1. Within the CAA and Baffin Bay, the El Niño-Southern Oscillation index correlates well with multiyear ice coverage (positive) and first-year ice coverage (negative) suggesting that El Niño episodes precede summers with more multiyear ice and less first-year ice. Extending the trend calculations back to 1960 along the major shipping routes revealed significant decreases in summer sea ice coverage ranging between 11% and 15% decade-1 along the route through Hudson Bay and 6% and 10% decade-1 along the southern route of the Northwest Passage, the latter is linked to increases in SAT. Between 1960 and 2008, no significant trends were found along the northern western Parry Channel route of the Northwest Passage.

Fermilab History and Archives Project | Home

Science.gov Websites

Fermilab History and Archives Project Fermilab History and Archives Project Fermi National Accelerator Laboratory Home About the Archives History & Archives Online Request Contact Us Site Index SEARCH the site: History & Archives Project Fermilab History and Archives Project The History of

Comparison of phytochemical profiles, antioxidant and cellular antioxidant activities of different varieties of blueberry (Vaccinium spp.).

PubMed

Wang, Huailing; Guo, Xinbo; Hu, Xiaodan; Li, Tong; Fu, Xiong; Liu, Rui Hai

2017-02-15

Numerous reports have demonstrated that the consumption of fruits and vegetables is beneficial for the human health. Blueberries, in particular, are rich in phytochemicals including free and bound forming. Phytochemical profiles of 14 varieties of blueberry were compared in this study. 12 compounds were analyzed and had significant changes in blueberry fruits. Total antioxidant activities in different blueberry varieties varied about 2.6times by oxygen radical absorbance capacity (ORAC) assay, and 2times by peroxyl radical scavenging capacity (PSC) assay. The cellular antioxidant activities (CAA) in different varieties varied about 3.9times without phosphate buffer saline (PBS) wash, and 4.7times with PBS wash by CAA assay. Blueberry extracts had potent antiproliferative activities against HepG2 human liver cancer cells, indicating the potential protective benefits associated with their use as functional foods. The anti-proliferative activity was observed to be dose-dependent in blueberry extracts. Copyright © 2016 Elsevier Ltd. All rights reserved.

Back to the Future: Long-Term Seismic Archives Revisited

NASA Astrophysics Data System (ADS)

Waldhauser, F.; Schaff, D. P.

2007-12-01

Archives of digital seismic data recorded by seismometer networks around the world have grown tremendously over the last several decades helped by the deployment of seismic stations and their continued operation within the framework of monitoring seismic activity. These archives typically consist of waveforms of seismic events and associated parametric data such as phase arrival time picks and the location of hypocenters. Catalogs of earthquake locations are fundamental data in seismology, and even in the Earth sciences in general. Yet, these locations have notoriously low spatial resolution because of errors in both the picks and the models commonly used to locate events one at a time. This limits their potential to address fundamental questions concerning the physics of earthquakes, the structure and composition of the Earth's interior, and the seismic hazards associated with active faults. We report on the comprehensive use of modern waveform cross-correlation based methodologies for high- resolution earthquake location - as applied to regional and global long-term seismic databases. By simultaneous re-analysis of two decades of the digital seismic archive of Northern California, reducing pick errors via cross-correlation and model errors via double-differencing, we achieve up to three orders of magnitude resolution improvement over existing hypocenter locations. The relocated events image networks of discrete faults at seismogenic depths across various tectonic settings that until now have been hidden in location uncertainties. Similar location improvements are obtained for earthquakes recorded at global networks by re- processing 40 years of parametric data from the ISC and corresponding waveforms archived at IRIS. Since our methods are scaleable and run on inexpensive Beowulf clusters, periodic re-analysis of entire archives may thus become a routine procedure to continuously improve resolution in existing catalogs. We demonstrate the role of seismic archives

Comprehensive planning of data archive in Japanese planetary missions

NASA Astrophysics Data System (ADS)

Yamamoto, Yukio; Shinohara, Iku; Hoshino, Hirokazu; Tateno, Naoki; Hareyama, Makoto; Okada, Naoki; Ebisawa, Ken

Comprehensive planning of data archive in Japanese planetary missions Japan Aerospace Exploration Agency (JAXA) provides HAYABUSA and KAGUYA data as planetary data archives. These data archives, however, were prepared independently. Therefore the inconsistency of data format has occurred, and the knowledge of data archiving activity is not inherited. Recently, the discussion of comprehensive planning of data archive has started to prepare up-coming planetary missions, which indicates the comprehensive plan of data archive is required in several steps. The framework of the comprehensive plan is divided into four items: Preparation, Evaluation, Preservation, and Service. 1. PREPARATION FRAMEWORK Data is classified into several types: raw data, level-0, 1, 2 processing data, ancillary data, and etc. The task of mission data preparation is responsible for instrument teams, but preparations beside mission data and support of data management are essential to make unified conventions and formats over instruments in a mission, and over missions. 2. EVALUATION FRAMEWORK There are two meanings of evaluation: format and quality. The format evaluation is often discussed in the preparation framework. The data quality evaluation which is often called quality assurance (QA) or quality control (QC) must be performed by third party apart from preparation teams. An instrument team has the initiative for the preparation itself, and the third-party group is organized to evaluate the instrument team's activity. 3. PRESERVATION FRAMEWORK The main topic of this framework is document management, archiving structure, and simple access method. The mission produces many documents in the process of the development. Instrument de-velopment is no exception. During long-term development of a mission, many documents are obsoleted and updated repeatedly. A smart system will help instrument team to reduce some troubles of document management and archiving task. JAXA attempts to follow PDS manners

(Per)Forming Archival Research Methodologies

ERIC Educational Resources Information Center

Gaillet, Lynee Lewis

2012-01-01

This article raises multiple issues associated with archival research methodologies and methods. Based on a survey of recent scholarship and interviews with experienced archival researchers, this overview of the current status of archival research both complicates traditional conceptions of archival investigation and encourages scholars to adopt…

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A Tale of Two Archives: PDS3/PDS4 Archiving and Distribution of Juno Mission Data

NASA Astrophysics Data System (ADS)

Stevenson, Zena; Neakrase, Lynn; Huber, Lyle; Chanover, Nancy J.; Beebe, Reta F.; Sweebe, Kathrine; Johnson, Joni J.

2017-10-01

The Juno mission to Jupiter, which was launched on 5 August 2011 and arrived at the Jovian system in July 2016, represents the last mission to be officially archived under the PDS3 archive standards. Modernization and availability of the newer PDS4 archive standard has prompted the PDS Atmospheres Node (ATM) to provide on-the-fly migration of Juno data from PDS3 to PDS4. Data distribution under both standards presents challenges in terms of how to present data to the end user in both standards, without sacrificing accessibility to the data or impacting the active PDS3 mission pipelines tasked with delivering the data on predetermined schedules. The PDS Atmospheres Node has leveraged its experience with prior active PDS4 missions (e.g., LADEE and MAVEN) and ongoing PDS3-to-PDS4 data migration efforts providing a seamless distribution of Juno data in both PDS3 and PDS4. When ATM receives a data delivery from the Juno Science Operations Center, the PDS3 labels are validated and then fed through PDS4 migration software built at ATM. Specifically, a collection of Python methods and scripts has been developed to make the migration process as automatic as possible, even when working with the more complex labels used by several of the Juno instruments. This is used to create all of the PDS4 data labels at once and build PDS4 archive bundles with minimal human effort. Resultant bundles are then validated against the PDS4 standard and released alongside the certified PDS3 versions of the same data. The newer design of the distribution pages provides access to both versions of the data, utilizing some of the enhanced capabilities of PDS4 to improve search and retrieval of Juno data. Webpages are designed with the intent of offering easy access to all documentation for Juno data as well as the data themselves in both standards for users of all experience levels. We discuss the structure and organization of the Juno archive and associated webpages as examples of joint PDS3/PDS4

EOSDIS: Archive and Distribution Systems in the Year 2000

NASA Technical Reports Server (NTRS)

Behnke, Jeanne; Lake, Alla

2000-01-01

Earth Science Enterprise (ESE) is a long-term NASA research mission to study the processes leading to global climate change. The Earth Observing System (EOS) is a NASA campaign of satellite observatories that are a major component of ESE. The EOS Data and Information System (EOSDIS) is another component of ESE that will provide the Earth science community with easy, affordable, and reliable access to Earth science data. EOSDIS is a distributed system, with major facilities at seven Distributed Active Archive Centers (DAACs) located throughout the United States. The EOSDIS software architecture is being designed to receive, process, and archive several terabytes of science data on a daily basis. Thousands of science users and perhaps several hundred thousands of non-science users are expected to access the system. The first major set of data to be archived in the EOSDIS is from Landsat-7. Another EOS satellite, Terra, was launched on December 18, 1999. With the Terra launch, the EOSDIS will be required to support approximately one terabyte of data into and out of the archives per day. Since EOS is a multi-mission program, including the launch of more satellites and many other missions, the role of the archive systems becomes larger and more critical. In 1995, at the fourth convening of NASA Mass Storage Systems and Technologies Conference, the development plans for the EOSDIS information system and archive were described. Five years later, many changes have occurred in the effort to field an operational system. It is interesting to reflect on some of the changes driving the archive technology and system development for EOSDIS. This paper principally describes the Data Server subsystem including how the other subsystems access the archive, the nature of the data repository, and the mass-storage I/O management. The paper reviews the system architecture (both hardware and software) of the basic components of the archive. It discusses the operations concept, code

Lessons learned from planetary science archiving

NASA Astrophysics Data System (ADS)

Zender, J.; Grayzeck, E.

2006-01-01

The need for scientific archiving of past, current, and future planetary scientific missions, laboratory data, and modeling efforts is indisputable. To quote from a message by G. Santayama carved over the entrance of the US Archive in Washington DC “Those who can not remember the past are doomed to repeat it.” The design, implementation, maintenance, and validation of planetary science archives are however disputed by the involved parties. The inclusion of the archives into the scientific heritage is problematic. For example, there is the imbalance between space agency requirements and institutional and national interests. The disparity of long-term archive requirements and immediate data analysis requests are significant. The discrepancy between the space missions archive budget and the effort required to design and build the data archive is large. An imbalance exists between new instrument development and existing, well-proven archive standards. The authors present their view on the problems and risk areas in the archiving concepts based on their experience acquired within NASA’s Planetary Data System (PDS) and ESA’s Planetary Science Archive (PSA). Individual risks and potential problem areas are discussed based on a model derived from a system analysis done upfront. The major risk for a planetary mission science archive is seen in the combination of minimal involvement by Mission Scientists and inadequate funding. The authors outline how the risks can be reduced. The paper ends with the authors view on future planetary archive implementations including the archive interoperability aspect.

Cooking techniques improve the levels of bioactive compounds and antioxidant activity in kale and red cabbage.

PubMed

Murador, Daniella Carisa; Mercadante, Adriana Zerlotti; de Rosso, Veridiana Vera

2016-04-01

The aim of this study is to investigate the effects of different home cooking techniques (boiling, steaming, and stir-frying) in kale and red cabbage, on the levels of bioactive compounds (carotenoids, anthocyanins and phenolic compounds) determined by high-performance liquid chromatography coupled with photodiode array and mass spectrometry detectors (HPLC-DAD-MS(n)), and on the antioxidant activity evaluated by ABTS, ORAC and cellular antioxidant activity (CAA) assays. The steaming technique resulted in a significant increase in phenolic content in kale (86.1%; p<0.001) whereas in red cabbage it was significantly reduced (34.6%; p<0.001). In the kale, steaming resulted in significant increases in antioxidant activity levels in all of the evaluation methods. In the red cabbage, boiling resulted in a significant increase in antioxidant activity using the ABTS assay but resulted in a significant decrease using the ORAC assay. According to the CAA assay, the stir-fried sample displayed the highest levels of antioxidant activity. Copyright © 2015 Elsevier Ltd. All rights reserved.

Archiving Derrida

ERIC Educational Resources Information Center

Morris, Marla

2003-01-01

Derrida's archive, broadly speaking, is brilliantly mad, for he digs exegetically into the most difficult textual material and combines the most unlikely texts--from Socrates to Freud, from postcards to encyclopedias, from madness(es) to the archive, from primal scenes to death. In this paper, the author would like to do a brief study of the…

Social Media and Archives: A Survey of Archive Users

ERIC Educational Resources Information Center

Washburn, Bruce; Eckert, Ellen; Proffitt, Merrilee

2013-01-01

In April and May of 2012, the Online Computer Library Center (OCLC) Research conducted a survey of users of archives to learn more about their habits and preferences. In particular, they focused on the roles that social media, recommendations, reviews, and other forms of user-contributed annotation play in archival research. OCLC surveyed faculty,…

Contents of the NASA ocean data system archive, version 11-90

NASA Technical Reports Server (NTRS)

Smith, Elizabeth A. (Editor); Lassanyi, Ruby A. (Editor)

1990-01-01

The National Aeronautics and Space Administration (NASA) Ocean Data System (NODS) archive at the Jet Propulsion Laboratory (JPL) includes satellite data sets for the ocean sciences and global-change research to facilitate multidisciplinary use of satellite ocean data. Parameters include sea-surface height, surface-wind vector, sea-surface temperature, atmospheric liquid water, and surface pigment concentration. NODS will become the Data Archive and Distribution Service of the JPL Distributed Active Archive Center for the Earth Observing System Data and Information System (EOSDIS) and will be the United States distribution site for Ocean Topography Experiment (TOPEX)/POSEIDON data and metadata.

Status of worldwide Landsat archive

USGS Publications Warehouse

Warriner, Howard W.

1987-01-01

In cooperation with the International Landsat community, and through the Landsat Technical Working Group (LTWG), NOAA is assembling information about the status of the Worldwide Landsat Archive. During LTWG 9, member nations agreed to participate in a survey of International Landsat data holding and of their archive experiences with Landsat data. The goal of the effort was two-fold; one, to document the Landsat archive to date, and, two, to ensure that specific nations' experience with long-term Landsat archival problems were available to others. The survey requested details such as amount of data held, the format of the archive holdings by Spacecraft/Sensor, and acquisition years; the estimated costs to accumulated process, and replace the data (if necessary); the storage space required, and any member nation's plans that would establish the insurance of continuing quality. As a group, the LTWG nations are concerned about the characteristics and reliability of long-term magnetic media storage. Each nation's experience with older data retrieval is solicited in the survey. This information will allow nations to anticipate and plan for required changes to their archival holdings. Also solicited were reports of any upgrades to a nation's archival system that are currently planned and all results of attempts to reduce archive holdings including methodology, current status, and the planned access rates and product support that are anticipated for responding to future archival usage.

The GTC Public Archive

NASA Astrophysics Data System (ADS)

Alacid, J. Manuel; Solano, Enrique

2015-12-01

The Gran Telescopio Canarias (GTC) archive is operational since November 2011. The archive, maintained by the Data Archive Unit at CAB in the framework of the Spanish Virtual Observatory project, provides access to both raw and science ready data and has been designed in compliance with the standards defined by the International Virtual Observatory Alliance (IVOA) to guarantee a high level of data accessibility and handling. In this presentation I will describe the main capabilities the GTC archive offers to the community, in terms of functionalities and data collections, to carry out an efficient scientific exploitation of GTC data.

Overcoming Geometry-Induced Stiffness with IMplicit-Explicit (IMEX) Runge-Kutta Algorithms on Unstructured Grids with Applications to CEM, CFD, and CAA

NASA Technical Reports Server (NTRS)

Kanevsky, Alex

2004-01-01

My goal is to develop and implement efficient, accurate, and robust Implicit-Explicit Runge-Kutta (IMEX RK) methods [9] for overcoming geometry-induced stiffness with applications to computational electromagnetics (CEM), computational fluid dynamics (CFD) and computational aeroacoustics (CAA). IMEX algorithms solve the non-stiff portions of the domain using explicit methods, and isolate and solve the more expensive stiff portions using implicit methods. Current algorithms in CEM can only simulate purely harmonic (up to lOGHz plane wave) EM scattering by fighter aircraft, which are assumed to be pure metallic shells, and cannot handle the inclusion of coatings, penetration into and radiation out of the aircraft. Efficient MEX RK methods could potentially increase current CEM capabilities by 1-2 orders of magnitude, allowing scientists and engineers to attack more challenging and realistic problems.

The ESA Planetary Science Archive User Group (PSA-UG)

NASA Astrophysics Data System (ADS)

Pio Rossi, Angelo; Cecconi, Baptiste; Fraenz, Markus; Hagermann, Axel; Heather, David; Rosenblatt, Pascal; Svedhem, Hakan; Widemann, Thomas

2014-05-01

ESA has established a Planetary Science Archive User Group (PSA-UG), with the task of offering independent advice to ESA's Planetary Science Archive (e.g. Heather et al., 2013). The PSA-UG is an official and independent body that continuously evaluates services and tools provided by the PSA to the community of planetary data scientific users. The group has been tasked with the following top level objectives: a) Advise ESA on future development of the PSA. b) Act as a focus for the interests of the scientific community. c) Act as an advocate for the PSA. d) Monitor the PSA activities. Based on this, the PSA-UG will report through the official ESA channels. Disciplines and subjects represented by PSA-UG members include: Remote Sensing of both Atmosphere and Solid Surfaces, Magnetospheres, Plasmas, Radio Science and Auxilliary data. The composition of the group covers ESA missions populating the PSA both now and in the near future. The first members of the PSA-UG were selected in 2013 and will serve for 3 years, until 2016. The PSA-UG will address the community through workshops, conferences and the internet. Written recommendations will be made to the PSA coordinator, and an annual report on PSA and the PSA-UG activities will be sent to the Solar System Exploration Working Group (SSEWG). Any member of the community and planetary data user can get in touch with individual members of the PSA-UG or with the group as a whole via the contacts provided on the official PSA-UG web-page: http://archives.esac.esa.int/psa/psa-ug. The PSA is accessible via: http://archives.esac.esa.int/psa References: Heather, D., Barthelemy, M., Manaud, N., Martinez, S., Szumlas, M., Vazquez, J. L., Osuna, P. and the PSA Development Team (2013) ESA's Planetary Science Archive: Status, Activities and Plans. EuroPlanet Sci. Congr. #EPSC2013-626

Cassini Archive Tracking System

NASA Technical Reports Server (NTRS)

Conner, Diane; Sayfi, Elias; Tinio, Adrian

2006-01-01

The Cassini Archive Tracking System (CATS) is a computer program that enables tracking of scientific data transfers from originators to the Planetary Data System (PDS) archives. Without CATS, there is no systematic means of locating products in the archive process or ensuring their completeness. By keeping a database of transfer communications and status, CATS enables the Cassini Project and the PDS to efficiently and accurately report on archive status. More importantly, problem areas are easily identified through customized reports that can be generated on the fly from any Web-enabled computer. A Web-browser interface and clearly defined authorization scheme provide safe distributed access to the system, where users can perform functions such as create customized reports, record a transfer, and respond to a transfer. CATS ensures that Cassini provides complete science archives to the PDS on schedule and that those archives are available to the science community by the PDS. The three-tier architecture is loosely coupled and designed for simple adaptation to multimission use. Written in the Java programming language, it is portable and can be run on any Java-enabled Web server.

Fermilab History and Archives Project | Norman F. Ramsey

Science.gov Websites

Fermilab History and Archives Project Fermilab History and Archives Project Fermilab History and Archives Project Home About the Archives History and Archives Online Request Contact Us History & ; Archives Project Fermilab History and Archives Project Norman F. Ramsey Back to History and Archives

HEASARC - The High Energy Astrophysics Science Archive Research Center

NASA Technical Reports Server (NTRS)

Smale, Alan P.

2011-01-01

The High Energy Astrophysics Science Archive Research Center (HEASARC) is NASA's archive for high-energy astrophysics and cosmic microwave background (CMB) data, supporting the broad science goals of NASA's Physics of the Cosmos theme. It provides vital scientific infrastructure to the community by standardizing science data formats and analysis programs, providing open access to NASA resources, and implementing powerful archive interfaces. Over the next five years the HEASARC will ingest observations from up to 12 operating missions, while serving data from these and over 30 archival missions to the community. The HEASARC archive presently contains over 37 TB of data, and will contain over 60 TB by the end of 2014. The HEASARC continues to secure major cost savings for NASA missions, providing a reusable mission-independent framework for reducing, analyzing, and archiving data. This approach was recognized in the NRC Portals to the Universe report (2007) as one of the HEASARC's great strengths. This poster describes the past and current activities of the HEASARC and our anticipated developments in coming years. These include preparations to support upcoming high energy missions (NuSTAR, Astro-H, GEMS) and ground-based and sub-orbital CMB experiments, as well as continued support of missions currently operating (Chandra, Fermi, RXTE, Suzaku, Swift, XMM-Newton and INTEGRAL). In 2012 the HEASARC (which now includes LAMBDA) will support the final nine-year WMAP data release. The HEASARC is also upgrading its archive querying and retrieval software with the new Xamin system in early release - and building on opportunities afforded by the growth of the Virtual Observatory and recent developments in virtual environments and cloud computing.

Analysis of the request patterns to the NSSDC on-line archive

NASA Technical Reports Server (NTRS)

Johnson, Theodore

1994-01-01

NASA missions, both for earth science and for space science, collect huge amounts of data, and the rate at which data is being gathered is increasing. For example, the EOSDIS project is expected to collect petabytes per year. In addition, these archives are being made available to remote users over the Internet. The ability to manage the growth of the size and request activity of scientific archives depends on an understanding of the access patterns of scientific users. The National Space Science Data Center (NSSDC) of NASA Goddard Space Flight Center has run their on-line mass storage archive of space data, the National Data Archive and Distribution Service (NDADS), since November 1991. A large world-wide space research community makes use of NSSDC, requesting more than 20,000 files per month. Since the initiation of their service, they have maintained log files which record all accesses the archive. In this report, we present an analysis of the NDADS log files. We analyze the log files, and discuss several issues, including caching, reference patterns, clustering, and system loading.

Ethics and Truth in Archival Research

ERIC Educational Resources Information Center

Tesar, Marek

2015-01-01

The complexities of the ethics and truth in archival research are often unrecognised or invisible in educational research. This paper complicates the process of collecting data in the archives, as it problematises notions of ethics and truth in the archives. The archival research took place in the former Czechoslovakia and its turbulent political…

A MySQL Based EPICS Archiver

DOE Office of Scientific and Technical Information (OSTI.GOV)

Christopher Slominski

2009-10-01

Archiving a large fraction of the EPICS signals within the Jefferson Lab (JLAB) Accelerator control system is vital for postmortem and real-time analysis of the accelerator performance. This analysis is performed on a daily basis by scientists, operators, engineers, technicians, and software developers. Archiving poses unique challenges due to the magnitude of the control system. A MySQL Archiving system (Mya) was developed to scale to the needs of the control system; currently archiving 58,000 EPICS variables, updating at a rate of 11,000 events per second. In addition to the large collection rate, retrieval of the archived data must also bemore » fast and robust. Archived data retrieval clients obtain data at a rate over 100,000 data points per second. Managing the data in a relational database provides a number of benefits. This paper describes an archiving solution that uses an open source database and standard off the shelf hardware to reach high performance archiving needs. Mya has been in production at Jefferson Lab since February of 2007.« less

Design and implementation of scalable tape archiver

NASA Technical Reports Server (NTRS)

Nemoto, Toshihiro; Kitsuregawa, Masaru; Takagi, Mikio

1996-01-01

In order to reduce costs, computer manufacturers try to use commodity parts as much as possible. Mainframes using proprietary processors are being replaced by high performance RISC microprocessor-based workstations, which are further being replaced by the commodity microprocessor used in personal computers. Highly reliable disks for mainframes are also being replaced by disk arrays, which are complexes of disk drives. In this paper we try to clarify the feasibility of a large scale tertiary storage system composed of 8-mm tape archivers utilizing robotics. In the near future, the 8-mm tape archiver will be widely used and become a commodity part, since recent rapid growth of multimedia applications requires much larger storage than disk drives can provide. We designed a scalable tape archiver which connects as many 8-mm tape archivers (element archivers) as possible. In the scalable archiver, robotics can exchange a cassette tape between two adjacent element archivers mechanically. Thus, we can build a large scalable archiver inexpensively. In addition, a sophisticated migration mechanism distributes frequently accessed tapes (hot tapes) evenly among all of the element archivers, which improves the throughput considerably. Even with the failures of some tape drives, the system dynamically redistributes hot tapes to the other element archivers which have live tape drives. Several kinds of specially tailored huge archivers are on the market, however, the 8-mm tape scalable archiver could replace them. To maintain high performance in spite of high access locality when a large number of archivers are attached to the scalable archiver, it is necessary to scatter frequently accessed cassettes among the element archivers and to use the tape drives efficiently. For this purpose, we introduce two cassette migration algorithms, foreground migration and background migration. Background migration transfers cassettes between element archivers to redistribute frequently accessed

University of Michigan lecture archiving and related activities of the U-M ATLAS Collaboratory Project

NASA Astrophysics Data System (ADS)

Herr, J.; Bhatnagar, T.; Goldfarb, S.; Irrer, J.; McKee, S.; Neal, H. A.

2008-07-01

Large scientific collaborations as well as universities have a growing need for multimedia archiving of meetings and courses. Collaborations need to disseminate training and news to their wide-ranging members, and universities seek to provide their students with more useful studying tools. The University of Michigan ATLAS Collaboratory Project has been involved in the recording and archiving of multimedia lectures since 1999. Our software and hardware architecture has been used to record events for CERN, ATLAS, many units inside the University of Michigan, Fermilab, the American Physical Society and the International Conference on Systems Biology at Harvard. Until 2006 our group functioned primarily as a tiny research/development team with special commitments to the archiving of certain ATLAS events. In 2006 we formed the MScribe project, using a larger scale, and highly automated recording system to record and archive eight University courses in a wide array of subjects. Several robotic carts are wheeled around campus by unskilled student helpers to automatically capture and post to the Web audio, video, slides and chalkboard images. The advances the MScribe project has made in automation of these processes, including a robotic camera operator and automated video processing, are now being used to record ATLAS Collaboration events, making them available more quickly than before and enabling the recording of more events.

The Ethics of Archival Research

ERIC Educational Resources Information Center

McKee, Heidi A.; Porter, James E.

2012-01-01

What are the key ethical issues involved in conducting archival research? Based on examination of cases and interviews with leading archival researchers in composition, this article discusses several ethical questions and offers a heuristic to guide ethical decision making. Key to this process is recognizing the person-ness of archival materials.…

Archive and records management-Fiscal year 2010 offline archive media trade study

USGS Publications Warehouse

Bodoh, Tom; Boettcher, Ken; Gacke, Ken; Greenhagen, Cheryl; Engelbrecht, Al

2010-01-01

This document is a trade study comparing offline digital archive storage technologies. The document compares and assesses several technologies and recommends which technologies could be deployed as the next generation standard for the U.S. Geological Survey (USGS). Archives must regularly migrate to the next generation of digital archive technology, and the technology selected must maintain data integrity until the next migration. This document is the fiscal year 2010 (FY10) revision of a study completed in FY01 and revised in FY03, FY04, FY06, and FY08.

[Information production by scientists and the history of science: typological study of personal archives].

PubMed

Silva, Maria Celina Soares de Mello E; Trancoso, Márcia Cristina Duarte

2015-01-01

This article addresses the study of document typology in the personal archives of scientists and its importance in the history of science studies and for the archivist's work. A brief history is presented of diplomatic to typological information, emphasizing that identifying document production activity as essential for its classification. The article illustrates personal archive characteristics as regards the diversity of documental types and, in particular, those belonging to physicists. Furthermore, it presents five examples of documental types found in the archives of physicists as examples of research in progress. It also highlights the elaboration of a glossary of different documental kinds and types found in the private archives of Museum of Astronomy and Related Sciences in Rio de Janeiro.

NASA's Astrophysics Data Archives

NASA Astrophysics Data System (ADS)

Hasan, H.; Hanisch, R.; Bredekamp, J.

2000-09-01

The NASA Office of Space Science has established a series of archival centers where science data acquired through its space science missions is deposited. The availability of high quality data to the general public through these open archives enables the maximization of science return of the flight missions. The Astrophysics Data Centers Coordinating Council, an informal collaboration of archival centers, coordinates data from five archival centers distiguished primarily by the wavelength range of the data deposited there. Data are available in FITS format. An overview of NASA's data centers and services is presented in this paper. A standard front-end modifyer called `Astrowbrowse' is described. Other catalog browsers and tools include WISARD and AMASE supported by the National Space Scince Data Center, as well as ISAIA, a follow on to Astrobrowse.

SODA: Smart Objects, Dumb Archives

NASA Technical Reports Server (NTRS)

Nelson, Michael L.; Maly, Kurt; Zubair, Mohammad; Shen, Stewart N. T.

2004-01-01

We present the Smart Object, Dumb Archive (SODA) model for digital libraries (DLs). The SODA model transfers functionality traditionally associated with archives to the archived objects themselves. We are exploiting this shift of responsibility to facilitate other DL goals, such as interoperability, object intelligence and mobility, and heterogeneity. Objects in a SODA DL negotiate presentation of content and handle their own terms and conditions. In this paper we present implementations of our smart objects, buckets, and our dumb archive (DA). We discuss the status of buckets and DA and how they are used in a variety of DL projects.

Creating a web-based digital photographic archive: one hospital library's experience.

PubMed

Marshall, Caroline; Hobbs, Janet

2017-04-01

Cedars-Sinai Medical Center is a nonprofit community hospital based in Los Angeles. Its history spans over 100 years, and its growth and development from the merging of 2 Jewish hospitals, Mount Sinai and Cedars of Lebanon, is also part of the history of Los Angeles. The medical library collects and maintains the hospital's photographic archive, to which retiring physicians, nurses, and an active Community Relations Department have donated photographs over the years. The collection was growing rapidly, it was impossible to display all the materials, and much of the collection was inaccessible to patrons. The authors decided to make the photographic collection more accessible to medical staff and researchers by purchasing a web-based digital archival package, Omeka. We decided what material should be digitized by analyzing archival reference requests and considering the institution's plan to create a Timeline Wall documenting and celebrating the history of Cedars-Sinai. Within 8 months, we digitized and indexed over 500 photographs. The digital archive now allows patrons and researchers to access the history of the hospital and enables the library to process archival references more efficiently.

Archiving, processing, and disseminating ASTER products at the USGS EROS Data Center

USGS Publications Warehouse

Jones, B.; Tolk, B.; ,

2002-01-01

The U.S. Geological Survey EROS Data Center archives, processes, and disseminates Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) data products. The ASTER instrument is one of five sensors onboard the Earth Observing System's Terra satellite launched December 18, 1999. ASTER collects broad spectral coverage with high spatial resolution at near infrared, shortwave infrared, and thermal infrared wavelengths with ground resolutions of 15, 30, and 90 meters, respectively. The ASTER data are used in many ways to understand local and regional earth-surface processes. Applications include land-surface climatology, volcanology, hazards monitoring, geology, agronomy, land cover change, and hydrology. The ASTER data are available for purchase from the ASTER Ground Data System in Japan and from the Land Processes Distributed Active Archive Center in the United States, which receives level 1A and level 1B data from Japan on a routine basis. These products are archived and made available to the public within 48 hours of receipt. The level 1A and level 1B data are used to generate higher level products that include routine and on-demand decorrelation stretch, brightness temperature at the sensor, emissivity, surface reflectance, surface kinetic temperature, surface radiance, polar surface and cloud classification, and digital elevation models. This paper describes the processes and procedures used to archive, process, and disseminate standard and on-demand higher level ASTER products at the Land Processes Distributed Active Archive Center.

Land Processes Distributed Active Archive Center (LP DAAC) 25th Anniversary Recognition "A Model for Government Partnerships". LP DAAC "History and a Look Forward"

NASA Technical Reports Server (NTRS)

Behnke, Jeanne; Doescher, Chris

2015-01-01

This presentation discusses 25 years of interactions between NASA and the USGS to manage a Land Processes Distributed Active Archive Center (LPDAAC) for the purpose of providing users access to NASA's rich collection of Earth Science data. The presentation addresses challenges, efforts and metrics on the performance.

Long-Term Preservation and Advanced Access Services to Archived Data: The Approach of a System Integrator

NASA Astrophysics Data System (ADS)

Petitjean, Gilles; de Hauteclocque, Bertrand

2004-06-01

EADS Defence and Security Systems (EADS DS SA) have developed an expertise as integrator of archive management systems for both their commercial and defence customers (ESA, CNES, EC, EUMETSAT, French MOD, US DOD, etc.), especially in Earth Observation and in Meteorology fields.The concern of valuable data owners is both their long-term preservation but also the integration of the archive in their information system with in particular an efficient access to archived data for their user community. The system integrator answers to this requirement by a methodology combining understanding of user needs, exhaustive knowledge of the existing solutions both for hardware and software elements and development and integration ability. The system integrator completes the facility development by support activities.The long-term preservation of archived data obviously involves a pertinent selection of storage media and archive library. This selection relies on storage technology survey but the selection criteria depend on the analysis of the user needs. The system integrator will recommend the best compromise for implementing an archive management facility, thanks to its knowledge and its independence of storage market and through the analysis of the user requirements. He will provide a solution, which is able to evolve to take advantage of the storage technology progress.But preserving the data for long-term is not only a question of storage technology. Some functions are required to secure the archive management system against contingency situation: multiple data set copies using operational procedures, active quality control of the archived data, migration policy optimising the cost of ownership.

Archiving Student Solutions with Tablet PCs in a Discussion-based Introductory Physics Class

NASA Astrophysics Data System (ADS)

Price, Edward; De Leone, Charles

2008-10-01

Many active learning based physics courses use whiteboards as a space for groups to respond to prompts based on short lab activities, problem solving, or inquiry-oriented activities. Whiteboards are volatile; once erased, the material is lost. Tablet PCs and software such as Ubiquitous Presenter can be used as digital whiteboards in active learning classes. This enables automatic capture and archiving of student work for online review by students, instructors, and researchers. We studied the use of digital whiteboards in an active-learning introductory physics course at California State University, San Marcos. In this paper we examine the archival features of digital whiteboards', and characterize the use of these features by students and instructors, and explore possible uses for researchers and curriculum developers.

A biological survey on the Ottoman Archive papers and determination of the D10 value

NASA Astrophysics Data System (ADS)

Kantoğlu, Ömer; Ergun, Ece; Ozmen, Dilan; Halkman, Hilal B. D.

2018-03-01

The Ottoman Archives have one of the richest archive collections in the world. However, not all the archived documents are well preserved and some undergo biodeterioration. Therefore, a rapid and promising treatment method is necessary to preserve the collection for following generations as heritage. Radiation presents as an alternative for the treatment of archival materials for this purpose. In this study, we conducted a survey to determine the contamination species and the D10 values of the samples obtained from the shelves of the Ottoman Archives. The samples also included several insect pests collected at using a pheromone trap placed in the archive storage room. With the exception of few localized problems, no active pest presence was observed. The D10 values of mold contamination and reference mold (A. niger) were found to be 1.0 and 0.68 kGy, respectively. Based on these results, it can be concluded that an absorbed dose of 6 kGy is required to remove the contamination from the materials stored in the Ottoman Archives.

Archives: New Horizons in Astronomy

NASA Astrophysics Data System (ADS)

Bobis, L.; Laurenceau, A.

2010-10-01

The scientific archives in the Paris Observatory's library date back to the XVIIth century. In addition to the preservation and the valorisation of these historic archives, the library is also responsible for the efficient and timely management of contemporary documents to ensure their optimum conservation and identification once they become historical. Oral, iconographic and electronic documents complement these paper archives.

Phenolic Acids Profiles and Cellular Antioxidant Activity in Tortillas Produced from Mexican Maize Landrace Processed by Nixtamalization and Lime Extrusion Cooking.

PubMed

Gaxiola-Cuevas, Nallely; Mora-Rochín, Saraid; Cuevas-Rodriguez, Edith Oliva; León-López, Liliana; Reyes-Moreno, Cuauhtémoc; Montoya-Rodríguez, Alvaro; Milán-Carrillo, Jorge

2017-09-01

Phenolic acids profiles, chemical antioxidant activities (ABTS and ORAC), as well as cellular antioxidant activity (CAA) of tortilla of Mexican native maize landraces elaborated from nixtamalization and lime cooking extrusion processes were studied. Both cooking procedures decreased total phenolics, chemicals antioxidant activity when compared to raw grains. Extruded tortillas retained 79.6-83.5%, 74.1-77.6% and 79.8-80.5% of total phenolics, ABTS and ORAC values, respectively, compared to 47.8-49.8%, 41.3-42.3% and 43.7-44.4% assayed in traditional tortillas, respectively. Approximately 72.5-88.2% of ferulic acid in raw grains and their tortillas were in the bound form. Regarding of the CAA initially found in raw grains, the retained percentage for traditional and extruded tortillas ranged from 47.4 to 48.7% and 72.8 to 77.5%, respectively. These results suggest that Mexican maize landrace used in this study could be considered for the elaboration of nixtamalized and extruded food products with nutraceutical potential.

Marine ferromanganese encrustations: Archives of changing oceans

USGS Publications Warehouse

Koschinsky, Andrea; Hein, James

2017-01-01

Marine iron–manganese oxide coatings occur in many shallow and deep-water areas of the global ocean and can form in three ways: 1) Fe–Mn crusts can precipitate from seawater onto rocks on seamounts; 2) Fe–Mn nodules can form on the sediment surface around a nucleus by diagenetic processes in sediment pore water; 3) encrustations can precipitate from hydrothermal fluids. These oxide coatings have been growing for thousands to tens of millions of years. They represent a vast archive of how oceans have changed, including variations of climate, ocean currents, geological activity, erosion processes on land, and even anthropogenic impact. A growing toolbox of age-dating methods and element and isotopic signatures are being used to exploit these archives.

Influences and interactions of inundation, peat, and snow on active layer thickness: Modeling Archive

DOE Data Explorer

Scott Painter; Ethan Coon; Cathy Wilson; Dylan Harp; Adam Atchley

2016-04-21

This Modeling Archive is in support of an NGEE Arctic publication currently in review [4/2016]. The Advanced Terrestrial Simulator (ATS) was used to simulate thermal hydrological conditions across varied environmental conditions for an ensemble of 1D models of Arctic permafrost. The thickness of organic soil is varied from 2 to 40cm, snow depth is varied from approximately 0 to 1.2 meters, water table depth was varied from -51cm below the soil surface to 31 cm above the soil surface. A total of 15,960 ensemble members are included. Data produced includes the third and fourth simulation year: active layer thickness, time of deepest thaw depth, temperature of the unfrozen soil, and unfrozen liquid saturation, for each ensemble member. Input files used to run the ensemble are also included.

Community archiving of imaging studies

NASA Astrophysics Data System (ADS)

Fritz, Steven L.; Roys, Steven R.; Munjal, Sunita

1996-05-01

The quantity of image data created in a large radiology practice has long been a challenge for available archiving technology. Traditional methods ofarchiving the large quantity of films generated in radiology have relied on warehousing in remote sites, with courier delivery of film files for historical comparisons. A digital community archive, accessible via a wide area network, represents a feasible solution to the problem of archiving digital images from a busy practice. In addition, it affords a physician caring for a patient access to imaging studies performed at a variety ofhealthcare institutions without the need to repeat studies. Security problems include both network security issues in the WAN environment and access control for patient, physician and imaging center. The key obstacle to developing a community archive is currently political. Reluctance to participate in a community archive can be reduced by appropriate design of the access mechanisms.

The COROT Archive at LAEFF

NASA Astrophysics Data System (ADS)

Velasco, Almudena; Gutiérrez, Raúl; Solano, Enrique; García-Torres, Miguel; López, Mauro; Sarro, Luis Manuel

We describe here the main capabilities of the COROT archive. The archive (http://sdc.laeff.inta.es/corotfa/jsp/searchform.jsp), managed at LAEFF in the framework of the Spanish Virtual Observatory (http://svo.laeff.inta.es), has been developed following the standards and requirements defined by IVOA (http://www.ivoa.net). The COROT archive at LAEFF will be publicly available by the end of 2008.

The extreme ultraviolet explorer archive

NASA Astrophysics Data System (ADS)

Polomski, E.; Drake, J. J.; Dobson, C.; Christian, C.

1993-09-01

The Extreme Ultrviolet Explorer (EUVE) public archive was created to handle the storage, maintenance, and distribution of EUVE data and ancillary documentation, information, and software. Access to the archive became available to the public on July 17, 1992, only 40 days after the launch of the EUVE satellite. A brief overview of the archive's contents and the various methods of access will be described.

Inactivation of Cg10062, a cis-3-chloroacrylic acid dehalogenase homologue in Corynebacterium glutamicum, by (R)- and (S)-oxirane-2-carboxylate: analysis and implications.

PubMed

Robertson, Brooklyn A; Johnson, William H; Lo, Herng-Hsiang; Whitman, Christian P

2008-08-19

( R)- and ( S)-oxirane-2-carboxylate were determined to be active site-directed irreversible inhibitors of the cis-3-chloroacrylic acid dehalogenase ( cis-CaaD) homologue Cg10062 found in Corynebacterium glutamicum. Kinetic analysis indicates that the ( R) enantiomer binds more tightly and is the more potent inhibitor, likely reflecting more favorable interactions with active site residues. Pro-1 is the sole site of covalent modification by the ( R) and ( S) enantiomers. Pro-1, Arg-70, Arg-73, and Glu-114, previously identified as catalytic residues in Cg10062, have also been implicated in the inactivation mechanism. Pro-1, Arg-70, and Arg-73 are essential residues for the process as indicated by the observation that the enzymes with the corresponding alanine mutations are not covalently modified by either enantiomer. The E114Q mutant slows covalent modification of Cg10062 but does not prevent it. The results are comparable to those found for the irreversible inactivation of cis-CaaD by ( R)-oxirane-2-carboxylate with two important distinctions: the alkylation of cis-CaaD is stereospecific, and Glu-114 does not take part in the cis-CaaD inactivation mechanism. Cg10062 exhibits low-level cis-CaaD and trans-3-chloroacrylic acid dehalogenase (CaaD) activities, with the cis-CaaD activity predominating. Hence, the preference of Cg10062 for the cis isomer correlates with the observation that the ( R) enantiomer is the more potent inactivator. Moreover, the factors responsible for the relaxed substrate specificity of Cg10062 may account for the stereoselective inactivation by the enantiomeric epoxides. Delineation of these factors would provide a more complete picture of the substrate specificity determinants for cis-CaaD. This study represents an important step toward this goal by setting the stage for a crystallographic analysis of inactivated Cg10062.

Comparison of sodium naphthenate and air-ionization corona discharge as surface treatments for the ethylene-tetrafluoroethylene polymer (ETFE) to improve adhesion between ETFE and acrylonitrile-butadiene-styrene polymer (ABS) in the presence of a cyanoacrylate adhesive (CAA)

NASA Astrophysics Data System (ADS)

Lucía Johanning-Solís, Ana; Stradi-Granados, Benito A.

2014-09-01

This study compares two ethylene-tetrafluoroethylene (ETFE) surface activation treatments, namely chemical attack with a solution of sodium naphthenate and plasma erosion via air-ionization corona discharge in order to improve the adhesive properties of the ETFE. An experimental design was prepared for both treatments in order to assess the effect of the treatment characteristics on the tensile load needed to break the bond between the ETFE and the acrylonitrile-butadiene-styrene polymer (ABS) formed with a cyanoacrylate adhesive (CAA) applied between them. The reason for the selection of this problem is that both polymers are frequently used in the biomedical industry for their properties, and they need to be joined firmly in biomedical devices, and the cyanoacrylate adhesive is the adhesive traditionally used for fluoropolymers, in this case the ETFE, and the same CAA has also shown good adhesion with ABS. However, the strength of the bond for the triplet ETFE-CAA-ABS has not been reported and the improvement of the strength of the bond with surface treatments is not found in scholarly journals for modern medical devices such as stents and snares. Both treatments were compared based on the aforementioned design of experiments. The case where ETFE receives no surface treatment serves as the reference. The results indicated that the three factors evaluated (initial drying of the material, temperature of the chemical bath, and immersion time), and their interactions have no significant effect over the tensile load at failure (tensile strength) of the adhesive bond being evaluated. For the air-ionization corona discharge treatment, two factors were evaluated: discharge exposition time and air pressure. The results obtained from this experimental design indicate that there is no significant difference between the levels of the factors evaluated. These results were unexpected as the ranges used were representative of the maximum ranges permissible in manufacturing

Archival Information Management System.

DTIC Science & Technology

1995-02-01

management system named Archival Information Management System (AIMS), designed to meet the audit trail requirement for studies completed under the...are to be archived to the extent that future reproducibility and interrogation of results will exist. This report presents a prototype information

The Hubble Spectroscopic Legacy Archive

NASA Astrophysics Data System (ADS)

Peeples, M.; Tumlinson, J.; Fox, A.; Aloisi, A.; Fleming, S.; Jedrzejewski, R.; Oliveira, C.; Ayres, T.; Danforth, C.; Keeney, B.; Jenkins, E.

2017-04-01

With no future space ultraviolet instruments currently planned, the data from the UV spectrographs aboard the Hubble Space Telescope have a legacy value beyond their initial science goals. The goal of the Hubble Spectroscopic Legacy Archive(HSLA) is to provide to the community new science-grade combined spectra for all publicly available data obtained by the Cosmic Origins Spectrograph (COS)and the Space Telescope Imaging Spectrograph (STIS). These data are packaged into "smart archives" according to target type and scientific themes to facilitate the construction of archival samples for common science uses. A new "quick look" capability makes the data easy for users to quickly access, assess the quality of,and download for archival science. The first generation of these products for the far-ultraviolet (FUV) modes of COS was made available online via the Mikulski Archive for Space Telescopes (MAST) in early 2016 and updated in early 2017; future releases will include COS/NUV and STIS/UV data.

A generic archive protocol and an implementation

NASA Technical Reports Server (NTRS)

Jordan, J. M.; Jennings, D. G.; Mcglynn, T. A.; Ruggiero, N. G.; Serlemitsos, T. A.

1992-01-01

Archiving vast amounts of data has become a major part of every scientific space mission today. The Generic Archive/Retrieval Services Protocol (GRASP) addresses the question of how to archive the data collected in an environment where the underlying hardware archives may be rapidly changing. GRASP is a device independent specification defining a set of functions for storing and retrieving data from an archive, as well as other support functions. GRASP is divided into two levels: the Transfer Interface and the Action Interface. The Transfer Interface is computer/archive independent code while the Action Interface contains code which is dedicated to each archive/computer addressed. Implementations of the GRASP specification are currently available for DECstations running Ultrix, Sparcstations running SunOS, and microVAX/VAXstation 3100's. The underlying archive is assumed to function as a standard Unix or VMS file system. The code, written in C, is a single suite of files. Preprocessing commands define the machine unique code sections in the device interface. The implementation was written, to the greatest extent possible, using only ANSI standard C functions.

About Fermilab - History and Archives Project

Science.gov Websites

Fermilab Organization Chart Diversity Architecture History and Archives Project Sustainability Nature Accommodations Recreation Architecture & History Nature/Ecology Order Fermilab Merchandise Online Education K Fermilab History and Archives Project Archives Project main page | Fermilab History main page A Brief

Intestinal Permeability and Cellular Antioxidant Activity of Phenolic Compounds from Mango (Mangifera indica cv. Ataulfo) Peels.

PubMed

Pacheco-Ordaz, Ramón; Antunes-Ricardo, Marilena; Gutiérrez-Uribe, Janet A; González-Aguilar, Gustavo A

2018-02-08

Mango ( Mangifera indica cv. Ataulfo) peel contains bound phenolics that may be released by alkaline or acid hydrolysis and may be converted into less complex molecules. Free phenolics from mango cv. Ataulfo peel were obtained using a methanolic extraction, and their cellular antioxidant activity (CAA) and permeability were compared to those obtained for bound phenolics released by alkaline or acid hydrolysis. Gallic acid was found as a simple phenolic acid after alkaline hydrolysis along with mangiferin isomers and quercetin as aglycone and glycosides. Only gallic acid, ethyl gallate, mangiferin, and quercetin were identified in the acid fraction. The acid and alkaline fractions showed the highest CAA (60.5% and 51.5%) when tested at 125 µg/mL. The value of the apparent permeability coefficient (Papp) across the Caco-2/HT-29 monolayer of gallic acid from the alkaline fraction was higher (2.61 × 10 -6 cm/s) than in the other fractions and similar to that obtained when tested pure (2.48 × 10 -6 cm/s). In conclusion, mango peels contain bound phenolic compounds that, after their release, have permeability similar to pure compounds and exert an important CAA. This finding can be applied in the development of nutraceuticals using this important by-product from the mango processing industry.

The GTC scientific archive

NASA Astrophysics Data System (ADS)

Gutiérrez, R.; Solano, E.

2011-11-01

At present, data management in telescopes ofclass 8-10 meters is very inefficient. The Gran Telescopio Canarias(GTC) scientific archive that is being developed by the Centro deAstrobiología (CAB) in the framework of the Spanish Virtual Observatoryis aimed at avoiding this situation, providing the telescope with anarchive accessible via internet, guaranteeing the accessibility,efficiency, visibility and data security demanded by a telescope of itsentity. The GTC archive will also be adapted to the standards defined bythe International Virtual Observatory, maximizing the visibility of thedata produced by the telescope. The main characteristics of the GTCscientific archive are described in this poster.

Building a cloud based distributed active archive data center

NASA Astrophysics Data System (ADS)

Ramachandran, Rahul; Baynes, Katie; Murphy, Kevin

2017-04-01

NASA's Earth Science Data System (ESDS) Program serves as a central cog in facilitating the implementation of NASA's Earth Science strategic plan. Since 1994, the ESDS Program has committed to the full and open sharing of Earth science data obtained from NASA instruments to all users. One of the key responsibilities of the ESDS Program is to continuously evolve the entire data and information system to maximize returns on the collected NASA data. An independent review was conducted in 2015 to holistically review the EOSDIS in order to identify gaps. The review recommendations were to investigate two areas: one, whether commercial cloud providers offer potential for storage, processing, and operational efficiencies, and two, the potential development of new data access and analysis paradigms. In response, ESDS has initiated several prototypes investigating the advantages and risks of leveraging cloud computing. This poster will provide an overview of one such prototyping activity, "Cumulus". Cumulus is being designed and developed as a "native" cloud-based data ingest, archive and management system that can be used for all future NASA Earth science data streams. The long term vision for Cumulus, its requirements, overall architecture, and implementation details, as well as lessons learned from the completion of the first phase of this prototype will be covered. We envision Cumulus will foster design of new analysis/visualization tools to leverage collocated data from all of the distributed DAACs as well as elastic cloud computing resources to open new research opportunities.

Sushi repeat-containing protein 1: a novel disease-associated molecule in cerebral amyloid angiopathy.

PubMed

Inoue, Yasuteru; Ueda, Mitsuharu; Tasaki, Masayoshi; Takeshima, Akari; Nagatoshi, Akihito; Masuda, Teruaki; Misumi, Yohei; Kosaka, Takayuki; Nomura, Toshiya; Mizukami, Mayumi; Matsumoto, Sayaka; Yamashita, Taro; Takahashi, Hitoshi; Kakita, Akiyoshi; Ando, Yukio

2017-10-01

Sporadic cerebral amyloid angiopathy (CAA) is characterized by cerebrovascular amyloid beta (Aβ) deposits and causes cerebral hemorrhage and dementia. The exact molecules that co-accumulate with cerebrovascular Aβ deposits are still not fully known. In our study here, we performed proteomic analyses with microdissected leptomeningeal arteries and cerebral neocortical arterioles from 8 cases with severe CAA, 12 cases with mild CAA, and 10 control cases without CAA, and we determined the levels of highly expressed proteins in cerebral blood vessels in CAA. We focused on sushi repeat-containing protein 1 (SRPX1), which is specifically expressed in CAA-affected cerebral blood vessels. Because SRPX1, which is known as a tumor suppressor gene, reportedly induced apoptosis in tumor cells, we hypothesized that SRPX1 may play an important role in Aβ-induced apoptosis in CAA. Immunohistochemical studies revealed that SRPX1 co-accumulated with Aβ deposits in cerebral blood vessels of all autopsied cases with severe CAA. In contrast, no SRPX1 co-accumulated with Aβ deposits in senile plaques. Furthermore, we demonstrated that both Aβ40 and Aβ42 bound to SRPX1 in vitro and enhanced SRPX1 expression in primary cultures of cerebrovascular smooth muscle cells. SRPX1 enhanced caspase activity induced by Aβ40. Knockdown of SRPX1, in contrast, reduced the formation of Aβ40 accumulations and the activity of caspase in cultured cerebrovascular smooth muscle cells. SRPX1 may thus be a novel molecule that is up-regulated in cerebrovascular Aβ deposits and that may increase Aβ-induced cerebrovascular degeneration in CAA.

A Background to Motion Picture Archives.

ERIC Educational Resources Information Center

Fletcher, James E.; Bolen, Donald L., Jr.

The emphasis of archives is on the maintenance and preservation of materials for scholarly research and professional reference. Archives may be established as separate entities or as part of a library or museum. Film archives may include camera originals (positive and negative), sound recordings, outtakes, scripts, contracts, advertising…

Migration Stories: Upgrading a PDS Archive to PDS4

NASA Astrophysics Data System (ADS)

Kazden, D. P.; Walker, R. J.; Mafi, J. N.; King, T. A.; Joy, S. P.; Moon, I. S.

2015-12-01

Increasing bandwidth, storage capacity and computational capabilities have greatly increased our ability to access data and use them. A significant challenge, however, is to make data archived under older standards useful in the new data environments. NASA's Planetary Data System (PDS) recently released version 4 of its information model (PDS4). PDS4 is an improvement and has advantages over previous versions. PDS4 adopts the XML standard for metadata and expresses structural requirements with XML Schema and content constraints by using Schematron. This allows for thorough validation by using off the shelf tools. This is a substantial improvement over previous PDS versions. PDS4 was designed to improve discoverability of products (resources) in a PDS archive. These additions allow for more uniform metadata harvesting from the collection level to the product level. New tools and services are being deployed that depend on the data adhering to the PDS4 model. However, the PDS has been an operational archive since 1989 and has large holdings that are compliant with previous versions of the PDS information model. The challenge is the make the older data accessible and useable with the new PDS4 based tools. To provide uniform utility and access to the entire archive the older data must be migrated to the PDS4 model. At the Planetary Plasma Interactions (PPI) Node of the PDS we've been actively planning and preparing to migrate our legacy archive to the new PDS4 standards for several years. With the release of the PDS4 standards we have begun the migration of our archive. In this presentation we will discuss the preparation of the data for the migration and how we are approaching this task. The presentation will consist of a series of stories to describe our experiences and the best practices we have learned.

The ESA Planetary Science Archive User Group (PSA-UG)

NASA Astrophysics Data System (ADS)

Rossi, A. P.; Cecconi, B.; Fraenz, M.; Hagermann, A.; Heather, D.; Rosenblatt, P.; Svedhem, H.; Widemann, T.

2014-04-01

ESA has established a Planetary Science Archive User Group (PSA-UG), with the task of offering independent advice to ESA's Planetary Science Archive (e.g. Heather et al., 2013). The PSA-UG is an official and independent body that continuously evaluates services and tools provided by the PSA to the community of planetary data scientific users. The group has been tasked with the following top level objectives: a) Advise ESA on future development of the PSA. b) Act as a focus for the interests of the scientific community. c) Act as an advocate for the PSA. d) Monitor the PSA activities. Based on this, the PSA-UG will report through the official ESA channels. Disciplines and subjects represented by PSA-UG members include: Remote Sensing of both Atmosphere and Solid Surfaces, Magnetospheres, Plasmas, Radio Science and Auxilliary data. The composition of the group covers ESA missions populating the PSA both now and in the near future. The first members of the PSA-UG were selected in 2013 and will serve for 3 years, until 2016. The PSA-UG will address the community through workshops, conferences and the internet. Written recommendations will be made to the PSA coordinator, and an annual report on PSA and the PSA-UG activities will be sent to the Solar System Exploration Working Group (SSEWG). Any member of the community and planetary data user can get in touch with individual members of the PSA-UG or with the group as a whole via the contacts provided on the official PSA-UG web-page: http://archives.esac.esa.int/psa/psa-ug The PSA is accessible via: http://archives.esac.esa.int/psa

Enterprise utilization of "always on-line" diagnostic study archive.

PubMed

McEnery, Kevin W; Suitor, Charles T; Thompson, Stephen K; Shepard, Jeffrey S; Murphy, William A

2002-01-01

To meet demands for enterprise image distribution, an "always on-line" image storage archive architecture was implemented before soft copy interpretation. It was presumed that instant availability of historical diagnostic studies would elicit a substantial utilization. Beginning November 1, 2000 an enterprise distribution archive was activated (Stentor, SanFrancisco, CA). As of August 8, 2001, 83,052 studies were available for immediate access without the need for retrieval from long-term archive. Image storage and retrieval logs for the period from June 12, 2001 to August 8, 2001 were analyzed. A total of 41,337 retrieval requests were noted for the 83,052 studies available as August 8, 2001. Computed radiography represented 16.8% of retrieval requests; digital radiography, 16.9%; computed tomography (CT), 44.5%; magnetic resonance (MR), 19.2%; and ultrasonography, 2.6%. A total of 51.5% of study retrievals were for studies less than 72 hours old. Study requests for cases greater than 100 days old represented 9.9% of all accessions, 9.7% of CT accessions, and 15.4% of MR accessions. Utilization of the archive indicates a substantial proportion of study retrievals for studies less than 72 hours after study completion. However, significant interest in historical CT and MR examinations was shown.

Internet FAQ Archives - Online Education - faqs.org

Science.gov Websites

faqs.org Internet FAQ Archives - Online Education faqs.org faqs.org - Internet FAQ Archives Internet FAQ Archives Online Education Internet RFC Index Usenet FAQ Index Other FAQs Documents Tools IFC Rated FAQs Internet RFC/STD/FYI/BCP Archives The Internet RFC series of documents is also available from

Image dissemination and archiving.

PubMed

Robertson, Ian

2007-08-01

Images generated as part of the sonographic examination are an integral part of the medical record and must be retained according to local regulations. The standard medical image format, known as DICOM (Digital Imaging and COmmunications in Medicine) makes it possible for images from many different imaging modalities, including ultrasound, to be distributed via a standard internet network to distant viewing workstations and a central archive in an almost seamless fashion. The DICOM standard is a truly universal standard for the dissemination of medical images. When purchasing an ultrasound unit, the consumer should research the unit's capacity to generate images in a DICOM format, especially if one wishes interconnectivity with viewing workstations and an image archive that stores other medical images. PACS, an acronym for Picture Archive and Communication System refers to the infrastructure that links modalities, workstations, the image archive, and the medical record information system into an integrated system, allowing for efficient electronic distribution and storage of medical images and access to medical record data.

Stewardship of very large digital data archives

NASA Technical Reports Server (NTRS)

Savage, Patric

1991-01-01

An archive is a permanent store. There are relatively few very large digital data archives in existence. Most business records are expired within five or ten years. Many kinds of business records that do have long lives are embedded in data bases that are continually updated and re-issued cyclically. Also, a great deal of permanent business records are actually archived as microfilm, fiche, or optical disk images - their digital version being an operational convenience rather than an archive. The problems forseen in stewarding the very large digital data archives that will accumulate during the mission of the Earth Observing System (EOS) are addressed. It focuses on the function of shepherding archived digital data into an endless future. Stewardship entails storing and protecting the archive and providing meaningful service to the community of users. The steward will (1) provide against loss due to physical phenomena; (2) assure that data is not lost due to storage technology obsolescence; and (3) maintain data in a current formatting methodology.

The NASA/IPAC Teacher Archive Research Program (NITARP) at Pierce College

NASA Astrophysics Data System (ADS)

Mallory, Carolyn R.; Feig, M.; Mahmud, N.; Silic, T.; Rebull, L.; Hoette, V.; Johnson, C.; McCarron, K.

2011-01-01

Our team from Pierce Community College, Woodland Hills, CA, participated in the NASA/IPAC Teacher Archive Research Program (NITARP) this past year (2010). (NITARP is described in another poster, Rebull et al.) Our team worked with archival Spitzer, 2MASS, and optical data to look for young stars in CG4, part of the Gum Nebula; our scientific results are described in a companion poster, Johnson et al. In this poster, we describe more about what we learned and how we incorporated our NITARP experiences into the Pierce College environment. Students developed critical thinking skills and an ability to organize their data analysis and develop a mental "big picture" of what is going on in the CG4 region. The NITARP program is one of several "Active Learning" programs going on at Pierce, and the other programs are briefly summarized in this poster as well. This program was made possible through the NASA/IPAC Teacher Archive Research Project (NITARP) and was funded by NASA Astrophysics Data Program and Archive Outreach funds.

An Integrative Approach to Archival Outreach: A Case Study of Becoming Part of the Constituents' Community

ERIC Educational Resources Information Center

Rettig, Patricia J.

2007-01-01

Archival outreach, an essential activity for any repository, should focus on what constituents are already doing and capitalize on existing venues related to the repository's subject area. The Water Resources Archive at Colorado State University successfully undertook this integrative approach to outreach. Detailed in the article are outreach…

HST archive primer, version 4.1

NASA Technical Reports Server (NTRS)

Fruchter, A. (Editor); Baum, S. (Editor)

1994-01-01

This version of the HST Archive Primer provides the basic information a user needs to know to access the HST archive via StarView the new user interface to the archive. Using StarView, users can search for observations interest, find calibration reference files, and retrieve data from the archive. Both the terminal version of StarView and the X-windows version feature a name resolver which simplifies searches of the HST archive based on target name. In addition, the X-windows version of StarView allows preview of all public HST data; compressed versions of public images are displayed via SAOIMAGE, while spectra are plotted using the public plotting package, XMGR. Finally, the version of StarView described here features screens designed for observers preparing Cycle 5 HST proposals.

Providing comprehensive and consistent access to astronomical observatory archive data: the NASA archive model

NASA Astrophysics Data System (ADS)

McGlynn, Thomas; Fabbiano, Giuseppina; Accomazzi, Alberto; Smale, Alan; White, Richard L.; Donaldson, Thomas; Aloisi, Alessandra; Dower, Theresa; Mazzerella, Joseph M.; Ebert, Rick; Pevunova, Olga; Imel, David; Berriman, Graham B.; Teplitz, Harry I.; Groom, Steve L.; Desai, Vandana R.; Landry, Walter

2016-07-01

Since the turn of the millennium a constant concern of astronomical archives have begun providing data to the public through standardized protocols unifying data from disparate physical sources and wavebands across the electromagnetic spectrum into an astronomical virtual observatory (VO). In October 2014, NASA began support for the NASA Astronomical Virtual Observatories (NAVO) program to coordinate the efforts of NASA astronomy archives in providing data to users through implementation of protocols agreed within the International Virtual Observatory Alliance (IVOA). A major goal of the NAVO collaboration has been to step back from a piecemeal implementation of IVOA standards and define what the appropriate presence for the US and NASA astronomy archives in the VO should be. This includes evaluating what optional capabilities in the standards need to be supported, the specific versions of standards that should be used, and returning feedback to the IVOA, to support modifications as needed. We discuss a standard archive model developed by the NAVO for data archive presence in the virtual observatory built upon a consistent framework of standards defined by the IVOA. Our standard model provides for discovery of resources through the VO registries, access to observation and object data, downloads of image and spectral data and general access to archival datasets. It defines specific protocol versions, minimum capabilities, and all dependencies. The model will evolve as the capabilities of the virtual observatory and needs of the community change.

Providing Comprehensive and Consistent Access to Astronomical Observatory Archive Data: The NASA Archive Model

NASA Technical Reports Server (NTRS)

McGlynn, Thomas; Guiseppina, Fabbiano A; Accomazzi, Alberto; Smale, Alan; White, Richard L.; Donaldson, Thomas; Aloisi, Alessandra; Dower, Theresa; Mazzerella, Joseph M.; Ebert, Rick;

The new European Hubble archive

NASA Astrophysics Data System (ADS)

De Marchi, Guido; Arevalo, Maria; Merin, Bruno

2016-01-01

The European Hubble Archive (hereafter eHST), hosted at ESA's European Space Astronomy Centre, has been released for public use in October 2015. The eHST is now fully integrated with the other ESA science archives to ensure long-term preservation of the Hubble data, consisting of more than 1 million observations from 10 different scientific instruments. The public HST data, the Hubble Legacy Archive, and the high-level science data products are now all available to scientists through a single, carefully designed and user friendly web interface. In this talk, I will show how the the eHST can help boost archival research, including how to search on sources in the field of view thanks to precise footprints projected onto the sky, how to obtain enhanced previews of imaging data and interactive spectral plots, and how to directly link observations with already published papers. To maximise the scientific exploitation of Hubble's data, the eHST offers connectivity to virtual observatory tools, easily integrates with the recently released Hubble Source Catalog, and is fully accessible through ESA's archives multi-mission interface.

Long-term data archiving

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moore, David Steven

2009-01-01

Long term data archiving has much value for chemists, not only to retain access to research and product development records, but also to enable new developments and new discoveries. There are some recent regulatory requirements (e.g., FDA 21 CFR Part 11), but good science and good business both benefit regardless. A particular example of the benefits of and need for long term data archiving is the management of data from spectroscopic laboratory instruments. The sheer amount of spectroscopic data is increasing at a scary rate, and the pressures to archive come from the expense to create the data (or recreatemore » it if it is lost) as well as its high information content. The goal of long-term data archiving is to save and organize instrument data files as well as any needed meta data (such as sample ID, LIMS information, operator, date, time, instrument conditions, sample type, excitation details, environmental parameters, etc.). This editorial explores the issues involved in long-term data archiving using the example of Raman spectral databases. There are at present several such databases, including common data format libraries and proprietary libraries. However, such databases and libraries should ultimately satisfy stringent criteria for long term data archiving, including readability for long times into the future, robustness to changes in computer hardware and operating systems, and use of public domain data formats. The latter criterion implies the data format should be platform independent and the tools to create the data format should be easily and publicly obtainable or developable. Several examples of attempts at spectral libraries exist, such as the ASTM ANDI format, and the JCAMP-DX format. On the other hand, proprietary library spectra can be exchanged and manipulated using proprietary tools. As the above examples have deficiencies according to the three long term data archiving criteria, Extensible Markup Language (XML; a product of the World Wide

A Pre-Steady State Kinetic Analysis of the αY60W mutant of trans-3-Chloroacrylic Acid Dehalogenase: Implications for the Mechanism of the Wild-type Enzyme†

PubMed Central

Huddleston, Jamison P.; Schroeder, Gottfried K.; Johnson, Kenneth A.; Whitman, Christian P.

2012-01-01

The bacterial degradation of the nematicide 1,3-dichloropropene, an isomeric mixture, requires the action of trans- and cis-3-chloracrylic acid dehalogenase (CaaD and cis-CaaD, respectively). Both enzymes are tautomerase superfamily members and share a core catalytic mechanism for the hydrolytic dehalogenation of the respective isomer of 3-haloacrylate. The observation that cis-CaaD requires two additional residues raises the question of how CaaD carries out a comparable reaction with fewer catalytic residues. As part of an effort to determine the basis for the apparently simpler CaaD-catalyzed reaction, the kinetic mechanism was determined by stopped-flow and chemical quench techniques using a fluorescent mutant form of the enzyme, αY60W-CaaD, and trans-3-bromoacrylate as the substrate. The data from these experiments as well as bromide inhibition studies are best accommodated by a six-step model that provides individual rate constants for substrate binding, chemistry, and a proposed conformational change occurring after chemistry followed by release of malonate semialdehyde and bromide. The conformational change and product release rates are comparable and together they limit the rate of turnover. The kinetic analysis and modeling studies validate the αY60W-CaaD mutant as an accurate reporter of active site events during the course of the enzyme-catalyzed reaction. The kinetic mechanism for the αY60W-CaaD-catalyzed reaction is comparable to that obtained for the cis-CaaD-catalyzed reaction. The kinetic model and the validated αY60W-CaaD mutant set the stage for an analysis of active site mutants to explore the contributions of individual catalytic residues and the basis for the simplicity of the reaction. PMID:23110338

New Developments At The Science Archives Of The NASA Exoplanet Science Institute

NASA Astrophysics Data System (ADS)

Berriman, G. Bruce

2018-06-01

The NASA Exoplanet Science Institute (NExScI) at Caltech/IPAC is the science center for NASA's Exoplanet Exploration Program and as such, NExScI operates three scientific archives: the NASA Exoplanet Archive (NEA) and Exoplanet Follow-up Observation Program Website (ExoFOP), and the Keck Observatory Archive (KOA).The NASA Exoplanet Archive supports research and mission planning by the exoplanet community by operating a service that provides confirmed and candidate planets, numerous project and contributed data sets and integrated analysis tools. The ExoFOP provides an environment for exoplanet observers to share and exchange data, observing notes, and information regarding the Kepler, K2, and TESS candidates. KOA serves all raw science and calibration observations acquired by all active and decommissioned instruments at the W. M. Keck Observatory, as well as reduced data sets contributed by Keck observers.In the coming years, the NExScI archives will support a series of major endeavours allowing flexible, interactive analysis of the data available at the archives. These endeavours exploit a common infrastructure based upon modern interfaces such as JuypterLab and Python. The first service will enable reduction and analysis of precision radial velocity data from the HIRES Keck instrument. The Exoplanet Archive is developing a JuypterLab environment based on the HIRES PRV interactive environment. Additionally, KOA is supporting an Observatory initiative to develop modern, Python based pipelines, and as part of this work, it has delivered a NIRSPEC reduction pipeline. The ensemble of pipelines will be accessible through the same environments.

Radio data archiving system

NASA Astrophysics Data System (ADS)

Knapic, C.; Zanichelli, A.; Dovgan, E.; Nanni, M.; Stagni, M.; Righini, S.; Sponza, M.; Bedosti, F.; Orlati, A.; Smareglia, R.

2016-07-01

Radio Astronomical Data models are becoming very complex since the huge possible range of instrumental configurations available with the modern Radio Telescopes. What in the past was the last frontiers of data formats in terms of efficiency and flexibility is now evolving with new strategies and methodologies enabling the persistence of a very complex, hierarchical and multi-purpose information. Such an evolution of data models and data formats require new data archiving techniques in order to guarantee data preservation following the directives of Open Archival Information System and the International Virtual Observatory Alliance for data sharing and publication. Currently, various formats (FITS, MBFITS, VLBI's XML description files and ancillary files) of data acquired with the Medicina and Noto Radio Telescopes can be stored and handled by a common Radio Archive, that is planned to be released to the (inter)national community by the end of 2016. This state-of-the-art archiving system for radio astronomical data aims at delegating as much as possible to the software setting how and where the descriptors (metadata) are saved, while the users perform user-friendly queries translated by the web interface into complex interrogations on the database to retrieve data. In such a way, the Archive is ready to be Virtual Observatory compliant and as much as possible user-friendly.

(abstract) Satellite Physical Oceanography Data Available From an EOSDIS Archive

NASA Technical Reports Server (NTRS)

Digby, Susan A.; Collins, Donald J.

1996-01-01

The Physical Oceanography Distributed Active Archive Center (PO.DAAC) at the Jet Propulsion Laboratory archives and distributes data as part of the Earth Observing System Data and Information System (EOSDIS). Products available from JPL are largely satellite derived and include sea-surface height, surface-wind speed and vectors, integrated water vapor, atmospheric liquid water, sea-surface temperature, heat flux, and in-situ data as it pertains to satellite data. Much of the data is global and spans fourteen years.There is email access, a WWW site, product catalogs, and FTP capabilities. Data is free of charge.

Astronomical Archive at Tartu Observatory

NASA Astrophysics Data System (ADS)

Annuk, K.

2007-10-01

Archiving astronomical data is important task not only at large observatories but also at small observatories. Here we describe the astronomical archive at Tartu Observatory. The archive consists of old photographic plate images, photographic spectrograms, CCD direct--images and CCD spectroscopic data. The photographic plate digitizing project was started in 2005. An on-line database (based on MySQL) was created. The database includes CCD data as well photographic data. A PHP-MySQL interface was written for access to all data.

Transportation plan repository and archive.

DOT National Transportation Integrated Search

2011-04-01

This project created a repository and archive for transportation planning documents in Texas within the : established Texas A&M Repository (http://digital.library.tamu.edu). This transportation planning archive : and repository provides ready access ...

Molecular screening of the Hbs Constant Spring (codon 142, TAA>CAA, α2) and Paksé (codon 142, TAA>TAT, α2) mutations in Thailand.

PubMed

Pichanun, Dalad; Munkongdee, Thongperm; Klamchuen, Sumonmaln; Butthep, Punnee; Winichagoon, Pranee; Fucharoen, Suthat; Svasti, Saovaros

2010-01-01

Hb Constant Spring [Hb CS, α142(H19)Term] and Hb Paksé [α142(H19)Term] occur from the mutation in the termination codon of the α2-globin gene, TAA>CAA (→Gln) and TAA>TAT (→Tyr), respectively. They are the most common nondeletional α-thalassemia (α-thal) variants causing Hb H disease in Southeast Asia. In this study, 587 cord blood samples were screened for the Hb CS and Hb Paksé mutations by a dot-blot hybridization technique using oligonucleotide probes specific for each mutation. The results showed that the prevalence of Hb CS and Hb Paksé in Central Thailand are 5.80 and 0.51%, respectively, which is in concordance with the results from previous studies.

Structural characterization of phenolic compounds and antioxidant activity of the phenolic-rich fraction from defatted adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) seed meal.

PubMed

Wang, Lifeng; Chen, Chao; Su, Anxiang; Zhang, Yiyi; Yuan, Jian; Ju, Xingrong

2016-04-01

The current study aims to investigate the antioxidant activities of various extracts from defatted adlay seed meal (DASM) based on the oxygen radical absorbance capacity (ORAC) assay, peroxyl radical scavenging capacity (PSC) assay and cellular antioxidant activity (CAA) assay. Of all the fractions, the n-butanol fraction exhibited the highest antioxidant activity, followed by crude acetone extract and aqueous fractions. Of the three sub-fractions obtained by Sephadex LH-20 chromatography, sub-fraction 3 possessed the highest antioxidant activity and total phenolic content. There was a strong positive correlation between the total phenolic content and the antioxidant activity. Based on HPLC-DAD-ESI-MS/MS analysis, the most abundant phenolic acid in sub-fraction 3 of DASM was ferulic acid at 67.28 mg/g, whereas the predominant flavonoid was rutin at 41.11 mg/g. Of the major individual compounds in sub-fraction 3, p-coumaric acid exhibited the highest ORAC values, and quercetin exhibited the highest PSC values and CAA values. Copyright © 2015 Elsevier Ltd. All rights reserved.

The French Astronomical Archives Alidade Project

NASA Astrophysics Data System (ADS)

Debarbat, S.; Bobis, L.

2004-12-01

The present state of Alidade, an archival project of Paris Observatory, including not only archival papers, but also instruments, documents, iconography, paintings etc., of various institutions, is described. Documents and collections, e.g. from donations or purchases, are still integrated into the archives, and selected material is displayed in temporary exhibits at the Observatory. Modern uses of old material are briefly mentioned

A Vision of Archival Education at the Millennium.

ERIC Educational Resources Information Center

Tibbo, Helen R.

1997-01-01

Issues critical to the development of an archival education degree program are discussed including number of credit hours and courses. Archival educators continue to revise the Society of American Archivists (SAA) Master's of Archival Studies (M.A.S.) guidelines as higher education and the world changes. Archival educators must cooperate with…

ASP archiving solution of regional HUSpacs.

PubMed

Pohjonen, Hanna; Kauppinen, Tomi; Ahovuo, Juhani

2004-09-01

The application service provider (ASP) model is not novel, but widely used in several non-health care-related business areas. In this article, ASP is described as a potential solution for long-term and back-up archiving of the picture archiving and communication system (PACS) of the Hospital District of Helsinki and Uusimaa (HUS). HUSpacs is a regional PACS for 21 HUS hospitals serving altogether 1.4 million citizens. The ultimate goal of this study was to define the specifications for the ASP archiving service and to compare different commercial options for archiving solutions (costs derived by unofficial requests for proposal): in-house PACS components, the regional ASP concept and the hospital-based ASP concept. In conclusion, the large scale of the HUS installation enables a cost-effective regional ASP archiving, resulting in a four to five times more economical solution than hospital-based ASP.

STScI Archive Manual, Version 7.0

NASA Astrophysics Data System (ADS)

Padovani, Paolo

1999-06-01

The STScI Archive Manual provides information a user needs to know to access the HST archive via its two user interfaces: StarView and a World Wide Web (WWW) interface. It provides descriptions of the StarView screens used to access information in the database and the format of that information, and introduces the use to the WWW interface. Using the two interfaces, users can search for observations, preview public data, and retrieve data from the archive. Using StarView one can also find calibration reference files and perform detailed association searches. With the WWW interface archive users can access, and obtain information on, all Multimission Archive at Space Telescope (MAST) data, a collection of mainly optical and ultraviolet datasets which include, amongst others, the International Ultraviolet Explorer (IUE) Final Archive. Both interfaces feature a name resolver which simplifies searches based on target name.

The ``One Archive'' for JWST

NASA Astrophysics Data System (ADS)

Greene, G.; Kyprianou, M.; Levay, K.; Sienkewicz, M.; Donaldson, T.; Dower, T.; Swam, M.; Bushouse, H.; Greenfield, P.; Kidwell, R.; Wolfe, D.; Gardner, L.; Nieto-Santisteban, M.; Swade, D.; McLean, B.; Abney, F.; Alexov, A.; Binegar, S.; Aloisi, A.; Slowinski, S.; Gousoulin, J.

2015-09-01

The next generation for the Space Telescope Science Institute data management system is gearing up to provide a suite of archive system services supporting the operation of the James Webb Space Telescope. We are now completing the initial stage of integration and testing for the preliminary ground system builds of the JWST Science Operations Center which includes multiple components of the Data Management Subsystem (DMS). The vision for astronomical science and research with the JWST archive introduces both solutions to formal mission requirements and innovation derived from our existing mission systems along with the collective shared experience of our global user community. We are building upon the success of the Hubble Space Telescope archive systems, standards developed by the International Virtual Observatory Alliance, and collaborations with our archive data center partners. In proceeding forward, the “one archive” architectural model presented here is designed to balance the objectives for this new and exciting mission. The STScI JWST archive will deliver high quality calibrated science data products, support multi-mission data discovery and analysis, and provide an infrastructure which supports bridges to highly valued community tools and services.

The Hubble Spectroscopic Legacy Archive

NASA Astrophysics Data System (ADS)

Peeples, Molly S.; Tumlinson, Jason; Fox, Andrew; Aloisi, Alessandra; Ayres, Thomas R.; Danforth, Charles; Fleming, Scott W.; Jenkins, Edward B.; Jedrzejewski, Robert I.; Keeney, Brian A.; Oliveira, Cristina M.

2016-01-01

With no future space ultraviolet instruments currently planned, the data from the UV spectrographs aboard the Hubble Space Telescope have a legacy value beyond their initial science goals. The Hubble Spectroscopic Legacy Archive will provide to the community new science-grade combined spectra for all publicly available data obtained by the Cosmic Origins Spectrograph (COS) and the Space Telescope Imaging Spectrograph (STIS). These data will be packaged into "smart archives" according to target type and scientific themes to facilitate the construction of archival samples for common science uses. A new "quick look" capability will make the data easy for users to quickly access, assess the quality of, and download for archival science starting in Cycle 24, with the first generation of these products for the FUV modes of COS available online via MAST in early 2016.

The JPL ASTER Volcano Archive: the development and capabilities of a 15 year global high resolution archive of volcano data.

NASA Astrophysics Data System (ADS)

Linick, J. P.; Pieri, D. C.; Sanchez, R. M.

2014-12-01

The physical and temporal systematics of the world's volcanic activity is a compelling and productive arena for the exercise of orbital remote sensing techniques, informing studies ranging from basic volcanology to societal risk. Comprised of over 160,000 frames and spanning 15 years of the Terra platform mission, the ASTER Volcano Archive (AVA: http://ava.jpl.nasa.gov) is the world's largest (100+Tb) high spatial resolution (15-30-90m/pixel), multi-spectral (visible-SWIR-TIR), downloadable (kml enabled) dedicated archive of volcano imagery. We will discuss the development of the AVA, and describe its growing capability to provide new easy public access to ASTER global volcano remote sensing data. AVA system architecture is designed to facilitate parameter-based data mining, and for the implementation of archive-wide data analysis algorithms. Such search and analysis capabilities exploit AVA's unprecedented time-series data compilations for over 1,550 volcanoes worldwide (Smithsonian Holocene catalog). Results include thermal anomaly detection and mapping, as well as detection of SO2 plumes from explosive eruptions and passive SO2 emissions confined to the troposphere. We are also implementing retrospective ASTER image retrievals based on volcanic activity reports from Volcanic Ash Advisory Centers (VAACs) and the US Air Force Weather Agency (AFWA). A major planned expansion of the AVA is currently underway, with the ingest of the full 1972-present LANDSAT, and NASA EO-1, volcano imagery for comparison and integration with ASTER data. Work described here is carried out under contract to NASA at the Jet Propulsion Laboratory as part of the California Institute of Technology.

Natural and Cultural Preservation - Complementary Endeavors through Soil Archive Research

NASA Astrophysics Data System (ADS)

Ackermann, Oren; Frumin, Suembikya; Kolska Horwitz, Liora; Maeir, Aren M.; Weiss, Ehud; Zhevelev, Helena M.

2016-04-01

Soil is an excellent archive for the history of landscape components such as ancient topography, erosion and accumulation processes, and vegetation characterization. In special cases, the soil archive even preserves botanical faunal and mollusc assemblages, allowing for the production of an archive of organic species as well. Long-term human activities in the past have left their imprints on certain landscape systems, leading to the formation of landscapes composed of both cultural and natural assets. The aim of this presentation is to suggest a conceptual model, based on the soil archive, which enables the preservation and sustainability of such environments. The proposed area (eastern Mediterranean) underwent cycles of ancient site establishment and abandonment. When areas were occupied, the natural vegetation around settlements experienced human interventions such as woodcutting, grazing and horticulture. During site abandonment, these interventions ceased, resulting in vegetation regeneration, a reduction in biodiversity, increased fire hazard, etc. This ultimately led to the deterioration of the landscape system as well as the destruction of cultural assets such as ancient buildings and/or remnants. In order to preserve and restore these sites, a conceptual model that combines both modern natural conservation strategies and restoration of traditional land-use techniques is proposed. This model provides a complementary approach to existing natural and cultural preservation efforts.

Intestinal Permeability and Cellular Antioxidant Activity of Phenolic Compounds from Mango (Mangifera indica cv. Ataulfo) Peels

PubMed Central

Pacheco-Ordaz, Ramón; González-Aguilar, Gustavo A.

2018-01-01

Mango (Mangifera indica cv. Ataulfo) peel contains bound phenolics that may be released by alkaline or acid hydrolysis and may be converted into less complex molecules. Free phenolics from mango cv. Ataulfo peel were obtained using a methanolic extraction, and their cellular antioxidant activity (CAA) and permeability were compared to those obtained for bound phenolics released by alkaline or acid hydrolysis. Gallic acid was found as a simple phenolic acid after alkaline hydrolysis along with mangiferin isomers and quercetin as aglycone and glycosides. Only gallic acid, ethyl gallate, mangiferin, and quercetin were identified in the acid fraction. The acid and alkaline fractions showed the highest CAA (60.5% and 51.5%) when tested at 125 µg/mL. The value of the apparent permeability coefficient (Papp) across the Caco-2/HT-29 monolayer of gallic acid from the alkaline fraction was higher (2.61 × 10−6 cm/s) than in the other fractions and similar to that obtained when tested pure (2.48 × 10−6 cm/s). In conclusion, mango peels contain bound phenolic compounds that, after their release, have permeability similar to pure compounds and exert an important CAA. This finding can be applied in the development of nutraceuticals using this important by-product from the mango processing industry. PMID:29419800

HEASARC Software Archive

NASA Technical Reports Server (NTRS)

White, Nicholas (Technical Monitor); Murray, Stephen S.

2003-01-01

(1) Chandra Archive: SAO has maintained the interfaces through which HEASARC gains access to the Chandra Data Archive. At HEASARC's request, we have implemented an anonymous ftp copy of a major part of the public archive and we keep that archive up-to- date. SAO has participated in the ADEC interoperability working group, establishing guidelines or interoperability standards and prototyping such interfaces. We have provided an NVO-based prototype interface, intending to serve the HEASARC-led NVO demo project. HEASARC's Astrobrowse interface was maintained and updated. In addition, we have participated in design discussions surrounding HEASARC's Caldb project. We have attended the HEASARC Users Group meeting and presented CDA status and developments. (2) Chandra CALDB: SA0 has maintained and expanded the Chandra CALDB by including four new data file types, defining the corresponding CALDB keyword/identification structures. We have provided CALDB upgrades for the public (CIAO) and for Standard Data Processing. Approximately 40 new files have been added to the CALDB in these version releases. There have been in the past year ten of these CALDB upgrades, each with unique index configurations. In addition, with the inputs from software, archive, and calibration scientists, as well as CIAO/SDP software developers, we have defined a generalized expansion of the existing CALDB interface and indexing structure. The purpose of this is to make the CALDB more generally applicable and useful in new and future missions that will be supported archivally by HEASARC. The generalized interface will identify additional configurational keywords and permit more extensive calibration parameter and boundary condition specifications for unique file selection. HEASARC scientists and developers from SAO and GSFC have become involved in this work, which is expected to produce a new interface for general use within the current year. (3) DS9: One of the decisions that came from last year

Archiving Microgravity Flight Data and Samples

NASA Technical Reports Server (NTRS)

1996-01-01

To obtain help in evaluating its current strategy for archiving data and samples obtained in microgravity research, NASA's Microgravity Science and Applications Division (MSAD) asked the Space Studies Board's Committee on Microgravity Research for guidance on the following questions: What data should be archived and where should it be kept? In what form should the data be maintained (electronic files, photographs, hard copy, samples)? What should the general format of the database be? To what extent should it be universally accessible and through what mechanisms? Should there be a period of time for which principal investigators have proprietary access? If so, how long should proprietary data be stored? What provisions should be made for data obtained from ground-based experiments? What should the deadline be for investigators placing their data in the archive? How long should data be saved? How long should data be easily accessible? As a prelude to making recommendations for optimum selection and storage of microgravity data and samples, the committee in this report briefly describes NASA's past archiving practices and outlines MSAD's current archiving strategy. Although the committee found that only a limited number of experiments have thus far been archived, it concluded that the general archiving strategy, characterized by MSAD as minimalist, appears viable. A central focus of attention is the Experiment Data Management Plan (EDMP), MSAD's recently instituted data management and archiving framework for flight experiments. Many of the report's recommendations are aimed at enhancing the effectiveness of the EDMP approach, which the committee regards as an appropriate data management method for MSAD. Other recommendations provide guidance on broader issues related to the questions listed above. This report does not address statutory or regulatory records retention requirements.

36 CFR 1253.1 - National Archives Building.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false National Archives Building... PUBLIC AVAILABILITY AND USE LOCATION OF RECORDS AND HOURS OF USE § 1253.1 National Archives Building. (a) The National Archives Building is located at 700 Pennsylvania Avenue, NW., Washington, DC 20408...

A Generic Archive Protocol and an Implementation

NASA Astrophysics Data System (ADS)

Jordan, J. M.; Jennings, D. G.; McGlynn, T. A.; Ruggiero, N. G.; Serlemitsos, T. A.

1993-01-01

Archiving vast amounts of data has become a major part of every scientific space mission today. GRASP, the Generic Retrieval/Ar\\-chive Services Protocol, addresses the question of how to archive the data collected in an environment where the underlying hardware archives and computer hosts may be rapidly changing.

SCA17 repeat expansion: mildly expanded CAG/CAA repeat alleles in neurological disorders and the functional implications.

PubMed

Chen, Chiung-Mei; Lee, Li-Ching; Soong, Bing-Wen; Fung, Hon-Chung; Hsu, Wen-Chuin; Lin, Pei-Ying; Huang, Hui-Ju; Chen, Fen-Lin; Lin, Cheng-Yueh; Lee-Chen, Guey-Jen; Wu, Yih-Ru

2010-03-01

Spinocerebellar ataxia type 17 (SCA17) involves the expression of a CAG/CAA expansion mutation in the gene encoding TATA-box binding protein (TBP), a general transcription initiation factor. The spectrum of SCA17 clinical presentation is broad. We screened for triplet expansion in the TBP gene in Taiwanese Parkinson's disease (PD), Alzheimer's disease (AD) and atypical parkinsonism and investigated the functional implication of expanded alleles using lymphoblastoid cells as a model. A total of 6 mildly expanded alleles (44-46) were identified in patients group. The frequency of the individuals carrying expanded alleles in PD (3/602 [0.5%]), AD (2/245 [0.8%]) and atypical parkinsonism (1/44 [2.3%]) is not significant as compared to that in the control subjects (0/644 [0.0%]). In lymphoblastoid cells, HSPA5, HSPA8 and HSPB1 expression levels in cells with expanded TBP were significantly lower than that of the control cells. Although not significantly, the levels of PARK7 protein isoforms 6.1 and 6.4 are notably increased in SCA17 lymphoblastoid cells. Treatment of TBH (tert-butyl hydroperoxide) significantly increases cell death in the cells with mildly expanded TBP. Our findings expand the spectrum of SCA17 phenotype and may contribute to our understanding of the disease. Copyright 2009 Elsevier B.V. All rights reserved.

The Preservation of Paper Collections in Archives.

ERIC Educational Resources Information Center

Adams, Cynthia Ann

The preservation methods used for paper collections in archives were studied through a survey of archives in the metropolitan Atlanta (Georgia) area. The preservation policy or program was studied, and the implications for conservators and preservation officers were noted. Twelve of 15 archives responded (response rate of 80 percent). Basic…

Records & Information Management Services | Alaska State Archives

Science.gov Websites

Search Search in: Archives State of Alaska Home About Records Management (RIMS) For Researchers Collections Imaging (IMS) ASHRAB Libraries, Archives, & Museums Archives Records Management (RIMS) Records records and information management for the State of Alaska. Frequently Asked Questions Submit Records

Picture archiving and communication in radiology.

PubMed

Napoli, Marzia; Nanni, Marinella; Cimarra, Stefania; Crisafulli, Letizia; Campioni, Paolo; Marano, Pasquale

2003-01-01

After over 80 years of exclusive archiving of radiologic films, at present, in Radiology, digital archiving is increasingly gaining ground. Digital archiving allows a considerable reduction in costs and space saving, but most importantly, immediate or remote consultation of all examinations and reports in the hospital clinical wards, is feasible. The RIS system, in this case, is the starting point of the process of electronic archiving which however is the task of PACS. The latter can be used as radiologic archive in accordance with the law provided that it is in conformance with some specifications as the use of optical long-term storage media or with electronic track of change. PACS archives, in a hierarchical system, all digital images produced by each diagnostic imaging modality. Images and patient data can be retrieved and used for consultation or remote consultation by the reporting radiologist who requires images and reports of previous radiologic examinations or by the referring physician of the ward. Modern PACS owing to the WEB server allow remote access to extremely simplified images and data however ensuring the due regulations and access protections. Since the PACS enables a simpler data communication within the hospital, security and patient privacy should be protected. A secure and reliable PACS should be able to minimize the risk of accidental data destruction, and should prevent non authorized access to the archive with adequate security measures in relation to the acquired knowledge and based on the technological advances. Archiving of data produced by modern digital imaging is a problem now present also in small Radiology services. The technology is able to readily solve problems which were extremely complex up to some years ago as the connection between equipment and archiving system owing also to the universalization of the DICOM 3.0 standard. The evolution of communication networks and the use of standard protocols as TCP/IP can minimize

The Design of Archives Buildings.

ERIC Educational Resources Information Center

Faye, Bernard

1982-01-01

Studies specific problems arising from design of archives buildings and examines three main purposes of this type of building, namely conservation, classification and restoration of archives, and the provision of access to them by administrators and research workers. Three references are listed. (Author/EJS)

Archival storage solutions for PACS

NASA Astrophysics Data System (ADS)

Chunn, Timothy

1997-05-01

While they are many, one of the inhibitors to the wide spread diffusion of PACS systems has been robust, cost effective digital archive storage solutions. Moreover, an automated Nearline solution is key to a central, sharable data repository, enabling many applications such as PACS, telemedicine and teleradiology, and information warehousing and data mining for research such as patient outcome analysis. Selecting the right solution depends on a number of factors: capacity requirements, write and retrieval performance requirements, scaleability in capacity and performance, configuration architecture and flexibility, subsystem availability and reliability, security requirements, system cost, achievable benefits and cost savings, investment protection, strategic fit and more.This paper addresses many of these issues. It compares and positions optical disk and magnetic tape technologies, which are the predominant archive mediums today. Price and performance comparisons will be made at different archive capacities, plus the effect of file size on storage system throughput will be analyzed. The concept of automated migration of images from high performance, high cost storage devices to high capacity, low cost storage devices will be introduced as a viable way to minimize overall storage costs for an archive. The concept of access density will also be introduced and applied to the selection of the most cost effective archive solution.

Building an archives in a medical library.

PubMed Central

Sammis, S K

1984-01-01

In 1979 the University of Medicine and Dentistry of New Jersey established an archives to collect, preserve, and retrieve important documentation related to its history. This paper examines various steps in building an archives and the development of a coherent collection policy, including potential sources for archival material. Problems and possible solutions concerning what to preserve from the vast quantities of material generated by an institution are considered. The relationship between the archives and the medical library and the requirements of the physical plant are discussed, including the storage and preservation of materials. PMID:6743876

Probiotic Properties and Cellular Antioxidant Activity of Lactobacillus plantarum MA2 Isolated from Tibetan Kefir Grains.

PubMed

Tang, Wei; Li, Chao; He, Zengguo; Pan, Fen; Pan, Shuo; Wang, Yanping

2017-11-20

Lactobacillus plantarum MA2 was isolated from traditional Chinese Tibetan kefir grains. Its antioxidant properties had been demonstrated in vitro and in vivo previously. In the present study, the probiotic characteristics of this strain were further evaluated by investigating its acid and bile salt tolerances, cell surface hydrophobicity, and autoaggregation, respectively. In addition, the cellular antioxidant activity (CAA) assay was applied to test the antioxidant capacity of the isolate in different growth phases. Same method was also used to evaluate the antioxidant capacity of its fermentation supernatant, cell-free extract, and intact cell quantitatively. The results of probiotic characteristic tests showed that MA2 could survive at pH 2.5 and 0.3% bile salt. Meanwhile, the measurements of cell surface hydrophobicity and autoaggregation were 45.29 ± 2.15 and 6.30 ± 0.34%, respectively. The results of cellular antioxidant activity tests indicated that MA2 had high antioxidant potential. The CAA value of logarithmic phase cell-free extract of MA2 (39,450.00 ± 424.05 μmol quercetin equivalents/100 g sample) was significantly higher than that in stationary phase cell-free extract (3395.98 ± 126.06 μmol quercetin equivalents/100 g sample) and that of fermentation supernatant in logarithmic phase (2174.41 ± 224.47 μmol quercetin equivalents/100 g sample) (p < 0.05). The CAA method was successively applied to evaluate the antioxidant capacity of MA2 in this study, which suggests that it could be used as a useful method for lactic acid bacteria antioxidant potential evaluation.

Rapid and Efficient Conversion of All-E-astaxanthin to 9Z- and 13Z-Isomers and Assessment of Their Stability and Antioxidant Activities.

PubMed

Yang, Cheng; Zhang, Lianfu; Zhang, Hua; Sun, Qingrui; Liu, Ronghua; Li, Jing; Wu, Leiyan; Tsao, Rong

2017-02-01

An optimized isomerization method was developed by heating all-E-astaxanthin in ethyl acetate (70 °C) with I-TiO 2 catalyst, yielding 22.7% and 16.9% of 9Z- and 13Z-astaxanthin, respectively, in 2 h, with 92-95% purity after semipreparative HPLC purification. 13Z-Astaxanthin had higher antioxidant activity than all-E- and 9Z-astaxanthins in oxygen radical absorbing capacity assay for lipophilic compounds, photochemiluminescence, and cellular antioxidant activity (CAA) assays, and 9Z-astaxanthin was higher in DPPH radical-scavenging activity assay and lower in CAA assay. All isomers were relatively stable between pH 2.0 and 11.6, except 13Z- and 9Z-astaxanthins at pH 2.0, suggesting they may be converted after passing the gastric phase in vivo. Metal ions did not significantly (p < 0.05) affect the stability. Results of the current study provides a means for further study into the mechanisms related to in vivo transformation and bioavailability of Z-astaxanthins, and their application in the development of functional foods and nutraceutical products.

Supporting users through integrated retrieval, processing, and distribution systems at the land processes distributed active archive center

USGS Publications Warehouse

Kalvelage, T.; Willems, Jennifer

2003-01-01

The design of the EOS Data and Information Systems (EOSDIS) to acquire, archive, manage and distribute Earth observation data to the broadest possible user community was discussed. A number of several integrated retrieval, processing and distribution capabilities have been explained. The value of these functions to the users were described and potential future improvements were laid out for the users. The users were interested in acquiring the retrieval, processing and archiving systems integrated so that they can get the data they want in the format and delivery mechanism of their choice.

The preservation of LANDSAT data by the National Land Remote Sensing Archive

NASA Technical Reports Server (NTRS)

Boyd, John E.

1992-01-01

Digital data, acquired by the National Landsat Remote Sensing Program, document nearly two decades of global agricultural, environmental, and sociological change. The data were widely applied and continue to be essential to a variety of geologic, hydrologic, agronomic, and strategic programs and studies by governmental, academic, and commercial researchers. Landsat data were acquired by five observatories that use primarily two digital sensor systems. The Multispectral Scanner (MSS) was onboard all five Landsats, which have orbited over 19 years; the higher resolution Thematic Mapper (TM) sensor acquired data for the last 9 years on Landsats 4 and 5 only. The National Land Remote Sensing Archive preserves the 800,000 scenes, which total more than 60 terabytes of data, on master tapes that are steadily deteriorating. Data are stored at two terabytes of data, on master tapes that are steadily deteriorating. Data are stored at two locations (Sioux Falls, South Dakota and Landover, Maryland), in three archive formats. The U.S. Geological Survey's EROS Data Center has initiated a project to consolidate and convert, over the next 4 years, two of the archive formats from antiquated instrumentation tape to rotary-recorded cassette magnetic tape. The third archive format, consisting of 300,000 scenes of MSS data acquired from 1972 through 1978, will not be converted because of budgetary constraints. This data preservation project augments EDC's experience in data archiving and information management, expertise that is critical to EDC's role as a Distributed Active Archive Center for the Earth Observing System, a new and much larger national earth science program.

System Security Authorization Agreement (SSAA) for the WIRE Archive and Research Facility

NASA Technical Reports Server (NTRS)

2002-01-01

The Wide-Field Infrared Explorer (WIRE) Archive and Research Facility (WARF) is operated and maintained by the Department of Physics, USAF Academy. The lab is located in Fairchild Hall, 2354 Fairchild Dr., Suite 2A103, USAF Academy, CO 80840. The WARF will be used for research and education in support of the NASA Wide Field Infrared Explorer (WIRE) satellite, and for related high-precision photometry missions and activities. The WARF will also contain the WIRE preliminary and final archives prior to their delivery to the National Space Science Data Center (NSSDC). The WARF consists of a suite of equipment purchased under several NASA grants in support of WIRE research. The core system consists of a Red Hat Linux workstation with twin 933 MHz PIII processors, 1 GB of RAM, 133 GB of hard disk space, and DAT and DLT tape drives. The WARF is also supported by several additional networked Linux workstations. Only one of these (an older 450 Mhz PIII computer running Red Hat Linux) is currently running, but the addition of several more is expected over the next year. In addition, a printer will soon be added. The WARF will serve as the primary research facility for the analysis and archiving of data from the WIRE satellite, together with limited quantities of other high-precision astronomical photometry data from both ground- and space-based facilities. However, the archive to be created here will not be the final archive; rather, the archive will be duplicated at the NSSDC and public access to the data will generally take place through that site.

Archives of Memory and Memories of Archive: CMS Women's Letters and Diaries 1823-35

ERIC Educational Resources Information Center

Fitzgerald, Tanya

2005-01-01

Searching for evidence written about or by women regarding past lives and experiences has raised challenges about what counts as an archive. Archives provide a form of connection between past and present and are a form of memory storing, memory-recording and memory-making. Records such as letters, diaries, and journals that may have been…

[Self-archiving of biomedical papers in open access repositories].

PubMed

Abad-García, M Francisca; Melero, Remedios; Abadal, Ernest; González-Teruel, Aurora

2010-04-01

Open-access literature is digital, online, free of charge, and free of most copyright and licensing restrictions. Self-archiving or deposit of scholarly outputs in institutional repositories (open-access green route) is increasingly present in the activities of the scientific community. Besides the benefits of open access for visibility and dissemination of science, it is increasingly more often required by funding agencies to deposit papers and any other type of documents in repositories. In the biomedical environment this is even more relevant by the impact scientific literature can have on public health. However, to make self-archiving feasible, authors should be aware of its meaning and the terms in which they are allowed to archive their works. In that sense, there are some tools like Sherpa/RoMEO or DULCINEA (both directories of copyright licences of scientific journals at different levels) to find out what rights are retained by authors when they publish a paper and if they allow to implement self-archiving. PubMed Central and its British and Canadian counterparts are the main thematic repositories for biomedical fields. In our country there is none of similar nature, but most of the universities and CSIC, have already created their own institutional repositories. The increase in visibility of research results and their impact on a greater and earlier citation is one of the most frequently advance of open access, but removal of economic barriers to access to information is also a benefit to break borders between groups.

Profiles of international archives: Les archives Jean Piaget, University of Geneva, Switzerland.

PubMed

Burman, Jeremy Trevelyan

2013-05-01

This research report provides a look behind closed doors at the Jean Piaget Archives in Geneva, Switzerland. It situates the potential visitor, contextualizes the Archives in its own history, and then describes what scholars can expect to find. New details about Piaget's views on Equal Rights and Equal Pay are also provided, including a look at how they affected the women who worked his factory (esp. Bärbel Inhelder). (PsycINFO Database Record (c) 2013 APA, all rights reserved).

The Protein Data Bank: unifying the archive

PubMed Central

Westbrook, John; Feng, Zukang; Jain, Shri; Bhat, T. N.; Thanki, Narmada; Ravichandran, Veerasamy; Gilliland, Gary L.; Bluhm, Wolfgang F.; Weissig, Helge; Greer, Douglas S.; Bourne, Philip E.; Berman, Helen M.

2002-01-01

The Protein Data Bank (PDB; http://www.pdb.org/) is the single worldwide archive of structural data of biological macromolecules. This paper describes the progress that has been made in validating all data in the PDB archive and in releasing a uniform archive for the community. We have now produced a collection of mmCIF data files for the PDB archive (ftp://beta.rcsb.org/pub/pdb/uniformity/data/mmCIF/). A utility application that converts the mmCIF data files to the PDB format (called CIFTr) has also been released to provide support for existing software. PMID:11752306

36 CFR 1280.66 - May I use the National Archives Library?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Archives Library? 1280.66 Section 1280.66 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS... the Washington, DC, Area? § 1280.66 May I use the National Archives Library? The National Archives Library facilities in the National Archives Building and in the National Archives at College Park are...

36 CFR 1280.66 - May I use the National Archives Library?

Code of Federal Regulations, 2014 CFR

2014-07-01

... Archives Library? 1280.66 Section 1280.66 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS... the Washington, DC, Area? § 1280.66 May I use the National Archives Library? The National Archives Library facilities in the National Archives Building and in the National Archives at College Park are...

36 CFR 1280.66 - May I use the National Archives Library?

Code of Federal Regulations, 2011 CFR

2011-07-01

... Archives Library? 1280.66 Section 1280.66 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS... the Washington, DC, Area? § 1280.66 May I use the National Archives Library? The National Archives Library facilities in the National Archives Building and in the National Archives at College Park are...

36 CFR 1280.66 - May I use the National Archives Library?

Code of Federal Regulations, 2012 CFR

2012-07-01

... Archives Library? 1280.66 Section 1280.66 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS... the Washington, DC, Area? § 1280.66 May I use the National Archives Library? The National Archives Library facilities in the National Archives Building and in the National Archives at College Park are...

Archives of Transformation: A Case Study of the International Women's Network against Militarism's Archival System

ERIC Educational Resources Information Center

Cachola, Ellen-Rae Cabebe

2014-01-01

This dissertation describes the International Women's Network Against Militarism's (IWNAM) political epistemology of security from an archival perspective, and how they create community archives to evidence this epistemology. This research examines records created by Women for Genuine Security (WGS) and Women's Voices Women Speak (WVWS), U.S. and…

European distributed seismological data archives infrastructure: EIDA

NASA Astrophysics Data System (ADS)

Clinton, John; Hanka, Winfried; Mazza, Salvatore; Pederson, Helle; Sleeman, Reinoud; Stammler, Klaus; Strollo, Angelo

2014-05-01

The European Integrated waveform Data Archive (EIDA) is a distributed Data Center system within ORFEUS that (a) securely archives seismic waveform data and related metadata gathered by European research infrastructures, and (b) provides transparent access to the archives for the geosciences research communities. EIDA was founded in 2013 by ORFEUS Data Center, GFZ, RESIF, ETH, INGV and BGR to ensure sustainability of a distributed archive system and the implementation of standards (e.g. FDSN StationXML, FDSN webservices) and coordinate new developments. Under the mandate of the ORFEUS Board of Directors and Executive Committee the founding group is responsible for steering and maintaining the technical developments and organization of the European distributed seismic waveform data archive and the integration within broader multidisciplanry frameworks like EPOS. EIDA currently offers uniform data access to unrestricted data from 8 European archives (www.orfeus-eu.org/eida), linked by the Arclink protocol, hosting data from 75 permanent networks (1800+ stations) and 33 temporary networks (1200+) stations). Moreover, each archive may also provide unique, restricted datasets. A webinterface, developed at GFZ, offers interactive access to different catalogues (EMSC, GFZ, USGS) and EIDA waveform data. Clients and toolboxes like arclink_fetch and ObsPy can connect directly to any EIDA node to collect data. Current developments are directed to the implementation of quality parameters and strong motion parameters.

NASA Data Archive Evaluation

NASA Technical Reports Server (NTRS)

Holley, Daniel C.; Haight, Kyle G.; Lindstrom, Ted

1997-01-01

The purpose of this study was to expose a range of naive individuals to the NASA Data Archive and to obtain feedback from them, with the goal of learning how useful people with varied backgrounds would find the Archive for research and other purposes. We processed 36 subjects in four experimental categories, designated in this report as C+R+, C+R-, C-R+ and C-R-, for computer experienced researchers, computer experienced non-researchers, non-computer experienced researchers, and non-computer experienced non-researchers, respectively. This report includes an assessment of general patterns of subject responses to the various aspects of the NASA Data Archive. Some of the aspects examined were interface-oriented, addressing such issues as whether the subject was able to locate information, figure out how to perform desired information retrieval tasks, etc. Other aspects were content-related. In doing these assessments, answers given to different questions were sometimes combined. This practice reflects the tendency of the subjects to provide answers expressing their experiences across question boundaries. Patterns of response are cross-examined by subject category in order to bring out deeper understandings of why subjects reacted the way they did to the archive. After the general assessment, there will be a more extensive summary of the replies received from the test subjects.

The Alaska Arctic Vegetation Archive (AVA-AK)

Treesearch

Donald A. Walker; Amy L. Breen; Lisa A. Druckenmiller; Lisa W. Wirth; Will Fisher; Martha K. Raynolds; Jozef Šibík; Marilyn D. Walker; Stephan Hennekens; Keith Boggs; Tina Boucher; Marcel Buchhorn; Helga Bültmann; David J. Cooper; Fred J.A Daniëls; Scott J. Davidson; James J. Ebersole; Sara C. Elmendorf; Howard E. Epstein; William A. Gould; Robert D. Hollister; Colleen M. Iversen; M. Torre Jorgenson; Anja Kade; Michael T. Lee; William H. MacKenzie; Robert K. Peet; Jana L. Peirce; Udo Schickhoff; Victoria L. Sloan; Stephen S. Talbot; Craig E. Tweedie; Sandra Villarreal; Patrick J. Webber; Donatella Zona

2016-01-01

The Alaska Arctic Vegetation Archive (AVA-AK, GIVD-ID: NA-US-014) is a free, publically available database archive of vegetation-plot data from the Arctic tundra region of northern Alaska. The archive currently contains 24 datasets with 3,026 non-overlapping plots. Of these, 74% have geolocation data with 25-m or better precision. Species cover data and header data are...

Archiving Space Geodesy Data for 20+ Years at the CDDIS

NASA Technical Reports Server (NTRS)

Noll, Carey E.; Dube, M. P.

2004-01-01

Since 1982, the Crustal Dynamics Data Information System (CDDIS) has supported the archive and distribution of geodetic data products acquired by NASA programs. These data include GPS (Global Positioning System), GLONASS (GLObal NAvigation Satellite System), SLR (Satellite Laser Ranging), VLBI (Very Long Baseline Interferometry), and DORIS (Doppler Orbitography and Radiolocation Integrated by Satellite). The data archive supports NASA's space geodesy activities through the Solid Earth and Natural Hazards (SENH) program. The CDDIS data system and its archive have become increasingly important to many national and international programs, particularly several of the operational services within the International Association of Geodesy (IAG), including the International GPS Service (IGS), the International Laser Ranging Service (ILRS), the International VLBI Service for Geodesy and Astrometry (IVS), the International DORIS Service (IDS), and the International Earth Rotation Service (IERS). The CDDIS provides easy and ready access to a variety of data sets, products, and information about these data. The specialized nature of the CDDIS lends itself well to enhancement and thus can accommodate diverse data sets and user requirements. All data sets and metadata extracted from these data sets are accessible to scientists through ftp and the web; general information about each data set is accessible via the web. The CDDIS, including background information about the system and its user communities, the computer architecture, archive contents, available metadata, and future plans will be discussed.

Fluvial deposits as an archive of early human activity: Progress during the 20 years of the Fluvial Archives Group

NASA Astrophysics Data System (ADS)

Chauhan, Parth R.; Bridgland, David R.; Moncel, Marie-Hélène; Antoine, Pierre; Bahain, Jean-Jacques; Briant, Rebecca; Cunha, Pedro P.; Despriée, Jackie; Limondin-Lozouet, Nicole; Locht, Jean-Luc; Martins, Antonio A.; Schreve, Danielle C.; Shaw, Andrew D.; Voinchet, Pierre; Westaway, Rob; White, Mark J.; White, Tom S.

2017-06-01

Fluvial sedimentary archives are important repositories for Lower and Middle Palaeolithic artefacts throughout the 'Old World', especially in Europe, where the beginning of their study coincided with the realisation that early humans were of great antiquity. Now that many river terrace sequences can be reliably dated and correlated with the globally valid marine isotope record, potentially useful patterns can be recognized in the distribution of the find-spots of the artefacts that constitute the large collections that were assembled during the years of manual gravel extraction. This paper reviews the advances during the past two decades in knowledge of hominin occupation based on artefact occurrences in fluvial contexts, in Europe, Asia and Africa. As such it is an update of a comparable review in 2007, at the end of IGCP Project no. 449, which had instigated the compilation of fluvial records from around the world during 2000-2004, under the auspices of the Fluvial Archives Group. An overarching finding is the confirmation of the well-established view that in Europe there is a demarcation between handaxe making in the west and flake-core industries in the east, although on a wider scale that pattern is undermined by the increased numbers of Lower Palaeolithic bifaces now recognized in East Asia. It is also apparent that, although it seems to have appeared at different places and at different times in the later Lower Palaeolithic, the arrival of Levallois technology as a global phenomenon was similarly timed across the area occupied by Middle Pleistocene hominins, at around 0.3 Ma.

Software for Managing an Archive of Images

NASA Technical Reports Server (NTRS)

Hallai, Charles; Jones, Helene; Callac, Chris

2003-01-01

This is a revised draft by Innovators concerning the report on Software for Managing and Archive of Images.The SSC Multimedia Archive is an automated electronic system to manage images, acquired both by film and digital cameras, for the Public Affairs Office (PAO) at Stennis Space Center (SSC). Previously, the image archive was based on film photography and utilized a manual system that, by todays standards, had become inefficient and expensive. Now, the SSC Multimedia Archive, based on a server at SSC, contains both catalogs and images for pictures taken both digitally and with a traditional film-based camera, along with metadata about each image.

In vitro antioxidant activities of the novel pentapeptides Ser-His-Glu-Cys-Asn and Leu-Pro-Phe-Ala-Met and the relationship between activity and peptide secondary structure.

PubMed

Yang, Ruiwen; Wang, Jia; Lin, Songyi; Ye, Haiqing; Chen, Feng

2017-04-01

Using high-performance liquid chromatography/tandem mass spectrometry, two novel antioxidant pentapeptides [Ser-His-Glu-Cys-Asn (SHECN) and Leu-Pro-Phe-Ala-Met (LPFAM)] were identified from 1-3-kDa soybean protein hydrolysates (SPH). The MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay was used to evaluate cytotoxicity in HepG2 cells. Antioxidant activity was measured using in vitro assays, including the cellular antioxidant activity assay (CAA), 2,2-diphenyl-1-picrylhydrazyl or 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) inhibition, and oxygen radical absorbance capacity (ORAC) assays. Finally, the secondary structure was determined using circular dichroism (CD). The results revealed that two novel peptides were nontoxic and possessed antioxidant activity. SHECN had significantly higher antioxidant activity than LPFAM (P < 0.05). The CAA value of SHECN was 776.22 µmol QE 100 g -1 . SHECN also showed significant DPPH inhibition (70.18 ± 4.06%) and ABTS inhibition (88.16 ± 0.76%). It had normalized ORAC values of 0.3000 ± 0.0070 µmol GE mg -1 and 0.0900 ± 0.0020 µmol TE mg -1 , respectively. The results of the CD analysis demonstrated that, compared to LPFAM, which had much lower antioxidant activity, SHECN had a high β-sheet content and reduced α-helix content. The results indicated that SHECN possessed high antioxidant activity. A higher β-sheet content and lower content levels of α-helix appear to be correlated with antioxidant activity. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

Life Sciences Data Archive (LSDA)

NASA Technical Reports Server (NTRS)

Fitts, M.; Johnson-Throop, Kathy; Thomas, D.; Shackelford, K.

2008-01-01

In the early days of spaceflight, space life sciences data were been collected and stored in numerous databases, formats, media-types and geographical locations. While serving the needs of individual research teams, these data were largely unknown/unavailable to the scientific community at large. As a result, the Space Act of 1958 and the Science Data Management Policy mandated that research data collected by the National Aeronautics and Space Administration be made available to the science community at large. The Biomedical Informatics and Health Care Systems Branch of the Space Life Sciences Directorate at JSC and the Data Archive Project at ARC, with funding from the Human Research Program through the Exploration Medical Capability Element, are fulfilling these requirements through the systematic population of the Life Sciences Data Archive. This program constitutes a formal system for the acquisition, archival and distribution of data for Life Sciences-sponsored experiments and investigations. The general goal of the archive is to acquire, preserve, and distribute these data using a variety of media which are accessible and responsive to inquiries from the science communities.

Managing an Archive of Images

NASA Technical Reports Server (NTRS)

Andres, Vince; Walter, David; Hallal, Charles; Jones, Helene; Callac, Chris

2004-01-01

The SSC Multimedia Archive is an automated electronic system to manage images, acquired both by film and digital cameras, for the Public Affairs Office (PAO) at Stennis Space Center (SSC). Previously, the image archive was based on film photography and utilized a manual system that, by today s standards, had become inefficient and expensive. Now, the SSC Multimedia Archive, based on a server at SSC, contains both catalogs and images for pictures taken both digitally and with a traditional, film-based camera, along with metadata about each image. After a "shoot," a photographer downloads the images into the database. Members of the PAO can use a Web-based application to search, view and retrieve images, approve images for publication, and view and edit metadata associated with the images. Approved images are archived and cross-referenced with appropriate descriptions and information. Security is provided by allowing administrators to explicitly grant access privileges to personnel to only access components of the system that they need to (i.e., allow only photographers to upload images, only PAO designated employees may approve images).

Challenges for Data Archival Centers in Evolving Environmental Sciences

NASA Astrophysics Data System (ADS)

Wei, Y.; Cook, R. B.; Gu, L.; Santhana Vannan, S. K.; Beaty, T.

2015-12-01

Environmental science has entered into a big data era as enormous data about the Earth environment are continuously collected through field and airborne missions, remote sensing observations, model simulations, sensor networks, etc. An open-access and open-management data infrastructure for data-intensive science is a major grand challenge in global environmental research (BERAC, 2010). Such an infrastructure, as exemplified in EOSDIS, GEOSS, and NSF EarthCube, will provide a complete lifecycle of environmental data and ensures that data will smoothly flow among different phases of collection, preservation, integration, and analysis. Data archival centers, as the data integration units closest to data providers, serve as the source power to compile and integrate heterogeneous environmental data into this global infrastructure. This presentation discusses the interoperability challenges and practices of geosciences from the aspect of data archival centers, based on the operational experiences of the NASA-sponsored Oak Ridge National Laboratory Distributed Active Archive Center (ORNL DAAC) and related environmental data management activities. Specifically, we will discuss the challenges to 1) encourage and help scientists to more actively share data with the broader scientific community, so that valuable environmental data, especially those dark data collected by individual scientists in small independent projects, can be shared and integrated into the infrastructure to tackle big science questions; 2) curate heterogeneous multi-disciplinary data, focusing on the key aspects of identification, format, metadata, data quality, and semantics to make them ready to be plugged into a global data infrastructure. We will highlight data curation practices at the ORNL DAAC for global campaigns such as BOREAS, LBA, SAFARI 2000; and 3) enhance the capabilities to more effectively and efficiently expose and deliver "big" environmental data to broad range of users and systems

76 FR 46855 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-03

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Agency Information Collection Activities: Proposed Collection; Comment Request AGENCY: National Archives and Records Administration (NARA). ACTION: Notice... original archival records in a National Archives and Records Administration facility. The public is invited...

Databases and archiving for cryoEM

PubMed Central

Patwardhan, Ardan; Lawson, Catherine L.

2017-01-01

Cryo-EM in structural biology is currently served by three public archives – EMDB for 3DEM reconstructions, PDB for models built from 3DEM reconstructions and EMPIAR for the raw 2D image data used to obtain the 3DEM reconstructions. These archives play a vital role for both the structural community and the wider biological community in making the data accessible so that results may be reused, reassessed and integrated with other structural and bioinformatics resources. The important role of the archives is underpinned by the fact that many journals mandate the deposition of data to PDB and EMDB on publication. The field is currently undergoing transformative changes where on the one hand high-resolution structures are becoming a routine occurrence while on the other hand electron tomography is enabling the study of macromolecules in the cellular context. Concomitantly the archives are evolving to best serve their stakeholder communities. In this chapter we describe the current state of the archives, resources available for depositing, accessing, searching, visualising and validating data, on-going community-wide initiatives and opportunities and challenges for the future. PMID:27572735

Caffeic acid ameliorates colitis in association with increased Akkermansia population in the gut microbiota of mice

PubMed Central

Zhang, Zhan; Wu, Xinyue; Cao, Shuyuan; Wang, Li; Wang, Di; Yang, Hui; Feng, Yiming; Wang, Shoulin; Li, Lei

2016-01-01

Emerging evidence shows that dietary agents and phytochemicals contribute to the prevention and treatment of ulcerative colitis (UC). We first reported the effects of dietary caffeic acid (CaA) on murine experimental colitis and on fecal microbiota. Colitis was induced in C57BL/6 mice by administration of 2.5% dextran sulfate sodium (DSS). Mice were fed a control diet or diet with CaA (1 mM). Our results showed that dietary CaA exerted anti-inflammatory effects in DSS colitis mice. Moreover, CaA could significantly suppress the secretion of IL-6, TNFα, and IFNγ and the colonic infiltration of CD3+ T cells, CD177+ neutrophils and F4/80+ macrophages via inhibition of the activation of NF-κB signaling pathway. Analysis of fecal microbiota showed that CaA could restore the reduction of richness and inhibit the increase of the ratio of Firmicute to Bacteroidetes in DSS colitis mice. And CaA could dramatically increase the proportion of the mucin-degrading bacterium Akkermansia in DSS colitis mice. Thus, CaA could ameliorate colonic pathology and inflammation in DSS colitis mice, and it might be associated with a proportional increase in Akkermansia. PMID:27177331

The Role of Data Archives in Synoptic Solar Physics

NASA Astrophysics Data System (ADS)

Reardon, Kevin

The detailed study of solar cycle variations requires analysis of recorded datasets spanning many years of observations, that is, a data archive. The use of digital data, combined with powerful database server software, gives such archives new capabilities to provide, quickly and flexibly, selected pieces of information to scientists. Use of standardized protocols will allow multiple databases, independently maintained, to be seamlessly joined, allowing complex searches spanning multiple archives. These data archives also benefit from being developed in parallel with the telescope itself, which helps to assure data integrity and to provide close integration between the telescope and archive. Development of archives that can guarantee long-term data availability and strong compatibility with other projects makes solar-cycle studies easier to plan and realize.

Technologically Enhanced Archival Collections: Using the Buddy System

ERIC Educational Resources Information Center

Holz, Dayna

2006-01-01

Based in the context of challenges faced by archives when managing digital projects, this article explores options of looking outside the existing expertise of archives staff to find collaborative partners. In teaming up with other departments and organizations, the potential scope of traditional archival digitization projects is expanded beyond…

Cassini/Huygens Program Archive Plan for Science Data

NASA Technical Reports Server (NTRS)

Conners, D.

2000-01-01

The purpose of this document is to describe the Cassini/Huygens science data archive system which includes policy, roles and responsibilities, description of science and supplementary data products or data sets, metadata, documentation, software, and archive schedule and methods for archive transfer to the NASA Planetary Data System (PDS).

Data archiving for animal cognition research: report of an NIMH workshop.

PubMed

Kurtzman, Howard S; Church, Russell M; Crystal, Jonathon D

2002-11-01

In July 2001, the National Institute of Mental Health sponsored a workshop titled "Data Archiving for Animal Cognition Research." Participants included scientists as well as experts in archiving, publishing, policy, and law. As is described in this report, the workshop resulted in a set of conclusions and recommendations concerning (A) the impact of data archiving on research, (B) how to incorporate data archiving into research practice, (C) contents of data archives, (D) technical and archival standards, and (E) organizational, financing, and policy issues. The animal cognition research community is encouraged to begin now to establish archives, deposit data and related materials, and make use of archived materials in new scientific projects.

A new archival infrastructure for highly-structured astronomical data

NASA Astrophysics Data System (ADS)

Dovgan, Erik; Knapic, Cristina; Sponza, Massimo; Smareglia, Riccardo

2018-03-01

With the advent of the 2020 Radio Astronomy Telescopes era, the amount and format of the radioastronomical data is becoming a massive and performance-critical challenge. Such an evolution of data models and data formats require new data archiving techniques that allow massive and fast storage of data that are at the same time also efficiently processed. A useful expertise for efficient archiviation has been obtained through data archiving of Medicina and Noto Radio Telescopes. The presented archival infrastructure named the Radio Archive stores and handles various formats, such as FITS, MBFITS, and VLBI's XML, which includes description and ancillary files. The modeling and architecture of the archive fulfill all the requirements of both data persistence and easy data discovery and exploitation. The presented archive already complies with the Virtual Observatory directives, therefore future service implementations will also be VO compliant. This article presents the Radio Archive services and tools, from the data acquisition to the end-user data utilization.

Comparison of the free and bound phenolic profiles and cellular antioxidant activities of litchi pulp extracts from different solvents

PubMed Central

2014-01-01

Background The phenolic contents and antioxidant activities of fruits could be underestimated if the bound phenolic compounds are not considered. In the present study, the extraction efficiencies of various solvents were investigated in terms of the total content of the free and bound phenolic compounds, as well as the phenolic profiles and antioxidant activities of the extracts. Methods Five different solvent mixtures were used to extract the free phenolic compounds from litchi pulp. Alkaline and acidic hydrolysis methods were compared for the hydrolysis of bound phenolic compounds from litchi pulp residue. The phenolic compositions of the free and bound fractions from the litchi pulp were identified using HPLC-DAD. The antioxidant activities of the litchi pulp extracts were determined by oxygen radical absorbance capacity (ORAC) and cellular antioxidant activity (CAA) assays. Results Of the solvents tested, aqueous acetone extracted the largest amount of total free phenolic compounds (210.7 mg GAE/100 g FW) from litchi pulp, followed sequentially by aqueous mixtures of methanol, ethanol and ethyl acetate, and water itself. The acid hydrolysis method released twice as many bound phenolic compounds as the alkaline hydrolysis method. Nine phenolic compounds were detected in the aqueous acetone extract. In contrast, not all of these compounds were found in the other four extracts. The classification and content of the bound phenolic compounds released by the acid hydrolysis method were higher than those achieved by the alkaline hydrolysis. The aqueous acetone extract showing the highest ORAC value (3406.9 μmol TE/100 g FW) for the free phenolic extracts. For the CAA method, however, the aqueous acetone and methanol extracts (56.7 and 55.1 μmol QE/100 g FW) showed the highest levels of activity of the five extracts tested. The ORAC and CAA values of the bound phenolic compounds obtained by acid hydrolysis were 2.6- and 1.9-fold higher than those obtained using the

Finding "Science" in the Archives of the Spanish Monarchy.

PubMed

Portuondo, Maria M

2016-03-01

This essay explores the history of several archives that house the early modern records of Spanish imperial science. The modern "archival turn" urges us to think critically about archives and to recognize in the history of these collections an embedded, often implicit, history that--unless properly recognized, acknowledged, and understood--can distort the histories we are trying to tell. This essay uses a curious episode in the history of science to illustrate how Spanish archives relate to each other and shape the collections they house. During the late eighteenth century a young navy officer, Martín Fernández de Navarrete, was dispatched to all the principal archives of the Spanish monarchy with a peculiar mission: he was to search for evidence that the Spanish in fact had a scientific tradition. This essay uses his mission to explain how the original purpose of an archive--the archive's telos--may persist as a strong and potentially deterministic force in the work of historians of science. In the case of the archives discussed, this telos was shaped by issues as wide ranging as defending a nation's reputation against claims of colonial neglect and as idiosyncratic as an archivist's selection criteria.

Lecture archiving on a larger scale at the University of Michigan and CERN

NASA Astrophysics Data System (ADS)

Herr, Jeremy; Lougheed, Robert; Neal, Homer A.

2010-04-01

The ATLAS Collaboratory Project at the University of Michigan has been a leader in the area of collaborative tools since 1999. Its activities include the development of standards, software and hardware tools for lecture archiving, and making recommendations for videoconferencing and remote teaching facilities. Starting in 2006 our group became involved in classroom recordings, and in early 2008 we spawned CARMA, a University-wide recording service. This service uses a new portable recording system that we developed. Capture, archiving and dissemination of rich multimedia content from lectures, tutorials and classes are increasingly widespread activities among universities and research institutes. A growing array of related commercial and open source technologies is becoming available, with several new products introduced in the last couple years. As the result of a new close partnership between U-M and CERN IT, a market survey of these products was conducted and a summary of the results are presented here. It is informing an ambitious effort in 2009 to equip many CERN rooms with automated lecture archiving systems, on a much larger scale than before. This new technology is being integrated with CERN's existing webcast, CDS, and Indico applications.

Living with a Red Dwarf: A Chandra Archival Study of dM Star Activity and Habitability

NASA Astrophysics Data System (ADS)

Engle, Scott

2017-09-01

We propose to analyze 6 archival Chandra visits, not pointed at, but serendipitously including 3 dM stars of known age. GJ 669 AB are a common proper motion pair, each are resolved and detected in 3 exposures, and LHS 373 is a much older dM star also detected on 3 exposures. Photometry (by us) of GJ 669 AB began 5 years ago, is ongoing, and has precisely determined rotation rates for both stars and evidence of frequent flaring from GJ 669 B. We will analyze the multiple exposures, derive an accurate mean level of X-ray activity from the targets, and also separate out and individually analyze and model any observed X-ray flares. This proposal will provide highly accurate coronal properties for the targets, but also very useful data for stellar evolution and planetary habitability studies.

Antioxidant Activity of Orange Flesh and Peel Extracted with Various Solvents

PubMed Central

Park, Jae-Hee; Lee, Minhee; Park, Eunju

2014-01-01

The aim of this study was to investigate the antioxidant activity of orange (Citrus auranthium) flesh (OF) and peel (OP) extracted with acetone, ethanol, and methanol. Antioxidant potential was examined by measuring total phenolic content (TPC), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity (RSA), total radical-trapping anti-oxidant potential (TRAP), oxygen radical absorbance capacity (ORAC), and cellular antioxidant activity (CAA). The comet assay was used to determine the protective effects of OF and OP against H2O2-induced DNA damage. TPC was highest in the acetone extracts of OF and OP. DPPH RSA was also higher in the acetone extracts than in the ethanol extracts. The DPPH RSA was highest in the acetone extracts of OF. The TRAP and ORAC values of the all extracts increased in a dose-dependent manner. In the TRAP assay, the acetone extracts of OF and OP had the lowest IC50 values. In the CAA assay, the methanol and acetone extracts of OP had the lowest IC50 values. All of the samples protected against H2O2-induced DNA damage in human leukocytes, as measured by the comet assay, but the acetone extracts of OP had the strongest effect. These results suggest that acetone is the best solvent for the extraction of antioxidant compounds from OF and OP. Furthermore, the high antioxidant activity of OP, which is a by-product of orange processing, suggests that it can be used in nutraceutical and functional foods. PMID:25580393

An enhanced archive facilitating climate impacts analysis

USGS Publications Warehouse

Maurer, E.P.; Brekke, L.; Pruitt, T.; Thrasher, B.; Long, J.; Duffy, P.; Dettinger, M.; Cayan, D.; Arnold, J.

2014-01-01

We describe the expansion of a publicly available archive of downscaled climate and hydrology projections for the United States. Those studying or planning to adapt to future climate impacts demand downscaled climate model output for local or regional use. The archive we describe attempts to fulfill this need by providing data in several formats, selectable to meet user needs. Our archive has served as a resource for climate impacts modelers, water managers, educators, and others. Over 1,400 individuals have transferred more than 50 TB of data from the archive. In response to user demands, the archive has expanded from monthly downscaled data to include daily data to facilitate investigations of phenomena sensitive to daily to monthly temperature and precipitation, including extremes in these quantities. New developments include downscaled output from the new Coupled Model Intercomparison Project phase 5 (CMIP5) climate model simulations at both the monthly and daily time scales, as well as simulations of surface hydrologi- cal variables. The web interface allows the extraction of individual projections or ensemble statistics for user-defined regions, promoting the rapid assessment of model consensus and uncertainty for future projections of precipitation, temperature, and hydrology. The archive is accessible online (http://gdo-dcp.ucllnl.org/downscaled_ cmip_projections).

Directory of Unesco Information Services: Library, Archives, and Documentation Centres = Repertoire des Services d'information de l'Unesco: bibliotheque, archives et centres de documentation.

ERIC Educational Resources Information Center

United Nations Educational, Scientific and Cultural Organization, Paris (France). Div. of Unesco Information Services.

Although primarily a directory of Unesco documentation centers and information units, this guide also provides information on the Main Library and the Unesco Archives. The listing for each of the nine centers includes information on any subdivisions of the center: (1) Bureau for Co-ordination of Operational Activities (BAO); (2) Culture and…

Digital Archival Image Collections: Who Are the Users?

ERIC Educational Resources Information Center

Herold, Irene M. H.

2010-01-01

Archival digital image collections are a relatively new phenomenon in college library archives. Digitizing archival image collections may make them accessible to users worldwide. There has been no study to explore whether collections on the Internet lead to users who are beyond the institution or a comparison of users to a national or…

Speeches Archive

Science.gov Websites

Speeches Archive Former AF Top 3 Viewpoints and Speeches Air Force Warrior Games 2017 Events 2018 Air Force Strategic Documents Desert Storm 25th Anniversary Observances DoD Warrior Games Portraits in Courage

BAO plate archive digitization

NASA Astrophysics Data System (ADS)

Mickaelian, A. M.; Nikoghosyan, E. H.; Gigoyan, K. S.; Paronyan, G. M.; Abrahamyan, H. V.; Andreasyan, H. R.; Azatyan, N. M.; Kostandyan, G. R.; Khachatryan, K. G.; Vardanyan, A. V.; Gyulzadyan, M. V.; Mikayelyan, G. A.; Farmanyan, S. V.; Knyazyan, A. V.

Astronomical plate archives created on the basis of numerous observations at many observatories are important part of the astronomical heritage. Byurakan Astrophysical Observatory (BAO) plate archive consists of 37,000 photographic plates and films, obtained at 2.6m telescope, 1m and 0.5m Schmidt telescopes and other smaller ones during 1947-1991. In 2015, we have started a project on the whole BAO Plate Archive digitization, creation of electronic database and its scientific usage. A Science Program Board is created to evaluate the observing material, to investigate new possibilities and to propose new projects based on the combined usage of these observations together with other world databases. The Executing Team consists of 11 astronomers and 2 computer scientists and will use 2 EPSON Perfection V750 Pro scanners for the digitization. The project will run during 3 years in 2015-2017 and the final result will be an electronic database and online interactive sky map to be used for further research projects.

Current status of the international Halley Watch infrared net archive

NASA Technical Reports Server (NTRS)

Mcguinness, Brian B.

1988-01-01

The primary purposes of the Halley Watch have been to promote Halley observations, coordinate and standardize the observing where useful, and to archive the results in a database readily accessible to cometary scientists. The intention of IHW is to store the observations themselves, along with any information necessary to allow users to understand and use the data, but to exclude interpretations of these data. Each of the archives produced by the IHW will appear in two versions: a printed archive and a digital archive on CD-ROMs. The archive is expected to have a very long lifetime. The IHW has already produced an archive for P/Crommelin. This consists of one printed volume and two 1600 bpi tapes. The Halley archive will contain at least twenty gigabytes of information.

Archiving for Rosetta: Lessons for IPDA

NASA Astrophysics Data System (ADS)

Heather, David

The Rosetta Project is unusual, possibly unique, in that all data must be archived both in NASA's Planetary Data System (PDS), and in ESA's Planetary Science Archive (PSA), ac-cording to an inter-agency agreement that predates the existence of ESA's PSA. This requires that all data are formatted according to NASA's PDS3 Standards. Scientific peer reviews of the data content for Rosetta have been carried out both in the US and in Europe and there was a very large overlap of the issues raised, illustrating the general scientific agreement, independent of geography, in what an archive must contain to be useful to the broader community of planetary scientists. However, validation of the data against the PDS Standards using both PSA and PDS devel-oped software has led to the discovery that many of the items that are validated are unstated assumptions in the written PDS Standards and are related, at least in large part, to how the two archiving systems operate rather than to the actual content that a scientist needs to use the data. The talk will illustrate some of these discrepancies with examples and suggest how to avoid such issues in future, optimizing the scientific return on the investment in archiving while minimizing the costs.

Longitudinal decrease in blood oxygenation level dependent response in cerebral amyloid angiopathy.

PubMed

Switzer, Aaron R; McCreary, Cheryl; Batool, Saima; Stafford, Randall B; Frayne, Richard; Goodyear, Bradley G; Smith, Eric E

2016-01-01

Lower blood oxygenation level dependent (BOLD) signal changes in response to a visual stimulus in functional magnetic resonance imaging (fMRI) have been observed in cross-sectional studies of cerebral amyloid angiopathy (CAA), and are presumed to reflect impaired vascular reactivity. We used fMRI to detect a longitudinal change in BOLD responses to a visual stimulus in CAA, and to determine any correlations between these changes and other established biomarkers of CAA progression. Data were acquired from 22 patients diagnosed with probable CAA (using the Boston Criteria) and 16 healthy controls at baseline and one year. BOLD data were generated from the 200 most active voxels of the primary visual cortex during the fMRI visual stimulus (passively viewing an alternating checkerboard pattern). In general, BOLD amplitudes were lower at one year compared to baseline in patients with CAA (p = 0.01) but were unchanged in controls (p = 0.18). The longitudinal difference in BOLD amplitudes was significantly lower in CAA compared to controls (p < 0.001). White matter hyperintensity (WMH) volumes and number of cerebral microbleeds, both presumed to reflect CAA-mediated vascular injury, increased over time in CAA (p = 0.007 and p = 0.001, respectively). Longitudinal increases in WMH (rs = 0.04, p = 0.86) or cerebral microbleeds (rs = -0.18, p = 0.45) were not associated with the longitudinal decrease in BOLD amplitudes.

Archiving California’s historical duck nesting data

USGS Publications Warehouse

Ackerman, Joshua T.; Herzog, Mark P.; Brady, Caroline; Eadie, John M.; Yarris, Greg S.

2015-07-14

With the conclusion of this project, most duck nest data have been entered, but all nest-captured hen data and other breeding waterfowl data that were outside the scope of this project have still not been entered and electronically archived. Maintaining an up-to-date archive will require additional resources to archive and enter the new duck nest data each year in an iterative process. Further, data proofing should be conducted whenever possible, and also should be considered an iterative process as there was sometimes missing data that could not be filled in without more direct knowledge of specific projects. Despite these disclaimers, this duck data archive represents a massive and useful dataset to inform future research and management questions.

Medical image digital archive: a comparison of storage technologies

NASA Astrophysics Data System (ADS)

Chunn, Timothy; Hutchings, Matt

1998-07-01

A cost effective, high capacity digital archive system is one of the remaining key factors that will enable a radiology department to eliminate film as an archive medium. The ever increasing amount of digital image data is creating the need for huge archive systems that can reliably store and retrieve millions of images and hold from a few terabytes of data to possibly hundreds of terabytes. Selecting the right archive solution depends on a number of factors: capacity requirements, write and retrieval performance requirements, scaleability in capacity and performance, conformance to open standards, archive availability and reliability, security, cost, achievable benefits and cost savings, investment protection, and more. This paper addresses many of these issues. It compares and positions optical disk and magnetic tape technologies, which are the predominant archive mediums today. New technologies will be discussed, such as DVD and high performance tape. Price and performance comparisons will be made at different archive capacities, plus the effect of file size on random and pre-fetch retrieval time will be analyzed. The concept of automated migration of images from high performance, RAID disk storage devices to high capacity, NearlineR storage devices will be introduced as a viable way to minimize overall storage costs for an archive.

"The Glory and Romance of Our History Are Here Preserved." An Introduction to the Records of the National Archives.

ERIC Educational Resources Information Center

National Archives and Records Administration, Washington, DC. Office of Public Programs.

This publication is intended for teachers bringing a class to visit the National Archives in Washington, D.C., for a workshop on primary documents. The National Archives serves as the repository for all federal records of enduring value. Primary sources are vital teaching tools because they actively engage the student's imagination so that he or…

Comparison of the Effects of the US Clean Air Act and of Smoking Prevention and Cessation Efforts on the Risk of Acute Myelogenous Leukemia

PubMed Central

Liu, Yan; Wu, Felicia; Lioy, Paul

2011-01-01

Objectives. We used 2 approaches based on published information to compare the impacts on leukemia incidence and benzene exposure of the 1990 US Clean Air Act (CAA) amendments and smoking prevention and cessation efforts. Methods. We extrapolated leukemia mortality related to community air pollution levels and to cigarette smoking from data from the US Environmental Protection Agency and the US Surgeon General. We also estimated relative decline in total exposures to benzene (a known human leukemogen) owing to the CAA amendments and to smoking prevention and cessation efforts. Results. We estimated that because of the CAA, there will be approximately 300 fewer leukemia deaths in the United States during the period 2000 through 2020. During the closest comparable period (1987–2007), we estimated that decline in cigarette smoking led to 7120 fewer leukemia deaths, of which 1282 to 3702 were attributable to benzene. Similarly, the decline in smoking led to about a tenfold greater decrease in total-population benzene exposure than did the 1990 CAA amendments. Conclusions. Both the CAA and smoking cessation activities contribute to a decrease in leukemia incidence. Smoking cessation activities have had a greater effect in the past. PMID:22021318

Comparison of the effects of the US Clean Air Act and of smoking prevention and cessation efforts on the risk of acute myelogenous leukemia.

PubMed

Goldstein, Bernard D; Liu, Yan; Wu, Felicia; Lioy, Paul

2011-12-01

We used 2 approaches based on published information to compare the impacts on leukemia incidence and benzene exposure of the 1990 US Clean Air Act (CAA) amendments and smoking prevention and cessation efforts. We extrapolated leukemia mortality related to community air pollution levels and to cigarette smoking from data from the US Environmental Protection Agency and the US Surgeon General. We also estimated relative decline in total exposures to benzene (a known human leukemogen) owing to the CAA amendments and to smoking prevention and cessation efforts. We estimated that because of the CAA, there will be approximately 300 fewer leukemia deaths in the United States during the period 2000 through 2020. During the closest comparable period (1987-2007), we estimated that decline in cigarette smoking led to 7120 fewer leukemia deaths, of which 1282 to 3702 were attributable to benzene. Similarly, the decline in smoking led to about a tenfold greater decrease in total-population benzene exposure than did the 1990 CAA amendments. Both the CAA and smoking cessation activities contribute to a decrease in leukemia incidence. Smoking cessation activities have had a greater effect in the past.

50 CFR 635.33 - Archival tags.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 50 Wildlife and Fisheries 12 2013-10-01 2013-10-01 false Archival tags. 635.33 Section 635.33 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE ATLANTIC HIGHLY MIGRATORY SPECIES Management Measures § 635.33 Archival tags. (a...

The new Gemini Observatory archive: a fast and low cost observatory data archive running in the cloud

NASA Astrophysics Data System (ADS)

Hirst, Paul; Cardenes, Ricardo

2016-08-01

We have developed and deployed a new data archive for the Gemini Observatory. Focused on simplicity and ease of use, the archive provides a number of powerful and novel features including automatic association of calibration data with the science data, and the ability to bookmark searches. A simple but powerful API allows programmatic search and download of data. The archive is hosted on Amazon Web Services, which provides us excellent internet connectivity and significant cost savings in both operations and development over more traditional deployment options. The code is written in python, utilizing a PostgreSQL database and Apache web server.

On missing Data Treatment for degraded video and film archives: a survey and a new Bayesian approach.

PubMed

Kokaram, Anil C

2004-03-01

Image sequence restoration has been steadily gaining in importance with the increasing prevalence of visual digital media. The demand for content increases the pressure on archives to automate their restoration activities for preservation of the cultural heritage that they hold. There are many defects that affect archived visual material and one central issue is that of Dirt and Sparkle, or "Blotches." Research in archive restoration has been conducted for more than a decade and this paper places that material in context to highlight the advances made during that time. The paper also presents a new and simpler Bayesian framework that achieves joint processing of noise, missing data, and occlusion.

Making geospatial data in ASF archive readily accessible

NASA Astrophysics Data System (ADS)

Gens, R.; Hogenson, K.; Wolf, V. G.; Drew, L.; Stern, T.; Stoner, M.; Shapran, M.

2015-12-01

The way geospatial data is searched, managed, processed and used has changed significantly in recent years. A data archive such as the one at the Alaska Satellite Facility (ASF), one of NASA's twelve interlinked Distributed Active Archive Centers (DAACs), used to be searched solely via user interfaces that were specifically developed for its particular archive and data sets. ASF then moved to using an application programming interface (API) that defined a set of routines, protocols, and tools for distributing the geospatial information stored in the database in real time. This provided a more flexible access to the geospatial data. Yet, it was up to user to develop the tools to get a more tailored access to the data they needed. We present two new approaches for serving data to users. In response to the recent Nepal earthquake we developed a data feed for distributing ESA's Sentinel data. Users can subscribe to the data feed and are provided with the relevant metadata the moment a new data set is available for download. The second approach was an Open Geospatial Consortium (OGC) web feature service (WFS). The WFS hosts the metadata along with a direct link from which the data can be downloaded. It uses the open-source GeoServer software (Youngblood and Iacovella, 2013) and provides an interface to include the geospatial information in the archive directly into the user's geographic information system (GIS) as an additional data layer. Both services are run on top of a geospatial PostGIS database, an open-source geographic extension for the PostgreSQL object-relational database (Marquez, 2015). Marquez, A., 2015. PostGIS essentials. Packt Publishing, 198 p. Youngblood, B. and Iacovella, S., 2013. GeoServer Beginner's Guide, Packt Publishing, 350 p.

36 CFR § 1280.66 - May I use the National Archives Library?

Code of Federal Regulations, 2013 CFR

2013-07-01

... Archives Library? § 1280.66 Section § 1280.66 Parks, Forests, and Public Property NATIONAL ARCHIVES AND... Facilities in the Washington, DC, Area? § 1280.66 May I use the National Archives Library? The National Archives Library facilities in the National Archives Building and in the National Archives at College Park...

Reference Model for an Open Archival Information System

NASA Technical Reports Server (NTRS)

1997-01-01

This document is a technical report for use in developing a consensus on what is required to operate a permanent, or indefinite long-term, archive of digital information. It may be useful as a starting point for a similar document addressing the indefinite long-term preservation of non-digital information. This report establishes a common framework of terms and concepts which comprise an Open Archival Information System (OAIS). It allows existing and future archives to be more meaningfully compared and contrasted. It provides a basis for further standardization of within an archival context and it should promote greater vendor awareness of, and support of , archival requirements. Through the process of normal evolution, it is expected that expansion, deletion, or modification to this document may occur. This report is therefore subject to CCSDS document management and change control procedures.

ModelArchiver—A program for facilitating the creation of groundwater model archives

USGS Publications Warehouse

Winston, Richard B.

2018-03-01

ModelArchiver is a program designed to facilitate the creation of groundwater model archives that meet the requirements of the U.S. Geological Survey (USGS) policy (Office of Groundwater Technical Memorandum 2016.02, https://water.usgs.gov/admin/memo/GW/gw2016.02.pdf, https://water.usgs.gov/ogw/policy/gw-model/). ModelArchiver version 1.0 leads the user step-by-step through the process of creating a USGS groundwater model archive. The user specifies the contents of each of the subdirectories within the archive and provides descriptions of the archive contents. Descriptions of some files can be specified automatically using file extensions. Descriptions also can be specified individually. Those descriptions are added to a readme.txt file provided by the user. ModelArchiver moves the content of the archive to the archive folder and compresses some folders into .zip files.As part of the archive, the modeler must create a metadata file describing the archive. The program has a built-in metadata editor and provides links to websites that can aid in creation of the metadata. The built-in metadata editor is also available as a stand-alone program named FgdcMetaEditor version 1.0, which also is described in this report. ModelArchiver updates the metadata file provided by the user with descriptions of the files in the archive. An optional archive list file generated automatically by ModelMuse can streamline the creation of archives by identifying input files, output files, model programs, and ancillary files for inclusion in the archive.

An Invitation to the ALA Archives.

ERIC Educational Resources Information Center

Beckel, Deborah; Brichford, Maynard

1984-01-01

Description of materials found in American Library Association Archives located at University of Illinois highlights 1905 letter defending Melvil Dewey, the 1900 Saguenay River Trip, children's librarians, library education, 1926 visit to President Coolidge by foreign librarians, and the American Library in Mexico. Notes on using the archives are…

Broadsides & Posters from the National Archives.

ERIC Educational Resources Information Center

National Archives and Records Administration, Washington, DC.

This booklet evolved from research for the exhibition "Uncle Sam Speaks: Broadsides and Posters from the National Archives," which opened at the National Archives in February 1986. The booklet is presented chronologically, beginning with broadsides from the American Revolution and ending with posters of the 1980's. Accompanying text…

Flexible server-side processing of climate archives

NASA Astrophysics Data System (ADS)

Juckes, Martin; Stephens, Ag; Damasio da Costa, Eduardo

2014-05-01

The flexibility and interoperability of OGC Web Processing Services are combined with an extensive range of data processing operations supported by the Climate Data Operators (CDO) library to facilitate processing of the CMIP5 climate data archive. The challenges posed by this peta-scale archive allow us to test and develop systems which will help us to deal with approaching exa-scale challenges. The CEDA WPS package allows users to manipulate data in the archive and export the results without first downloading the data -- in some cases this can drastically reduce the data volumes which need to be transferred and greatly reduce the time needed for the scientists to get their results. Reductions in data transfer are achieved at the expense of an additional computational load imposed on the archive (or near-archive) infrastructure. This is managed with a load balancing system. Short jobs may be run in near real-time, longer jobs will be queued. When jobs are queued the user is provided with a web dashboard displaying job status. A clean split between the data manipulation software and the request management software is achieved by exploiting the extensive CDO library. This library has a long history of development to support the needs of the climate science community. Use of the library ensures that operations run on data by the system can be reproduced by users using the same operators installed on their own computers. Examples using the system deployed for the CMIP5 archive will be shown and issues which need to be addressed as archive volumes expand into the exa-scale will be discussed.

Flexible server-side processing of climate archives

NASA Astrophysics Data System (ADS)

Juckes, M. N.; Stephens, A.; da Costa, E. D.

2013-12-01

The flexibility and interoperability of OGC Web Processing Services are combined with an extensive range of data processing operations supported by the Climate Data Operators (CDO) library to facilitate processing of the CMIP5 climate data archive. The challenges posed by this peta-scale archive allow us to test and develop systems which will help us to deal with approaching exa-scale challenges. The CEDA WPS package allows users to manipulate data in the archive and export the results without first downloading the data -- in some cases this can drastically reduce the data volumes which need to be transferred and greatly reduce the time needed for the scientists to get their results. Reductions in data transfer are achieved at the expense of an additional computational load imposed on the archive (or near-archive) infrastructure. This is managed with a load balancing system. Short jobs may be run in near real-time, longer jobs will be queued. When jobs are queued the user is provided with a web dashboard displaying job status. A clean split between the data manipulation software and the request management software is achieved by exploiting the extensive CDO library. This library has a long history of development to support the needs of the climate science community. Use of the library ensures that operations run on data by the system can be reproduced by users using the same operators installed on their own computers. Examples using the system deployed for the CMIP5 archive will be shown and issues which need to be addressed as archive volumes expand into the exa-scale will be discussed.

Getting from then to now: Sustaining the Lesbian Herstory Archives as a lesbian organization.

PubMed

Smith-Cruz, Shawn ta; Rando, Flavia; Corbman, Rachel; Edel, Deborah; Gwenwald, Morgan; Nestle, Joan; Thistlethwaite, Polly

2016-01-01

This article is a compilation of six narratives written by collective members of the volunteer-run Lesbian Herstory Archives, the oldest and largest collection of lesbian material in the world. Narratives draw on a yearlong series of conversations, which culminated in a panel discussion at the 40th Anniversary celebration. Authors' narratives detail the significance of the Lesbian Herstory Archives as a successful and sustainable lesbian organization. Topics covered span four decades and include: the organization's history and practice, founding and activism, the acquisition of the current space, community engagement, and processing of special collections.

A system approach to archival storage

NASA Technical Reports Server (NTRS)

Corcoran, John W.

1991-01-01

The introduction and viewgraphs of a discussion on a system approach to archival storage presented at the National Space Science Data Center (NSSDC) Mass Storage Workshop is included. The use of D-2 iron particles for archival storage is discussed along with how acceleration factors relating short-term tests to archival life times can be justified. Ampex Recording Systems is transferring D-2 video technology to data storage applications, and encountering concerns about corrosion. To protect the D-2 standard, Battelle tests were done on all four tapes in the Class 2 environment. Error rates were measured before and after the test on both exposed and control groups.

Digitized Archival Primary Sources in STEM: A Selected Webliography

ERIC Educational Resources Information Center

Jankowski, Amy

2017-01-01

Accessibility and findability of digitized archival resources can be a challenge, particularly for students or researchers not familiar with archival formats and digital interfaces, which adhere to different descriptive standards than more widely familiar library resources. Numerous aggregate archival collection databases exist, which provide a…

36 CFR 1253.1 - National Archives Building.

Code of Federal Regulations, 2012 CFR

2012-07-01

.... Hours for the Research Center and the Central Research Room are posted at http://www.archives.gov. The exhibit areas' hours of operation are also posted at http://www.archives.gov. Last admission to the...

36 CFR 1253.1 - National Archives Building.

Code of Federal Regulations, 2011 CFR

2011-07-01

.... Hours for the Research Center and the Central Research Room are posted at http://www.archives.gov. The exhibit areas' hours of operation are also posted at http://www.archives.gov. Last admission to the...

36 CFR 1253.1 - National Archives Building.

Code of Federal Regulations, 2014 CFR

2014-07-01

.... Hours for the Research Center and the Central Research Room are posted at http://www.archives.gov. The exhibit areas' hours of operation are also posted at http://www.archives.gov. Last admission to the...

Life Sciences Data Archive Scientific Development

NASA Technical Reports Server (NTRS)

Buckey, Jay C., Jr.

1995-01-01

The Life Sciences Data Archive will provide scientists, managers and the general public with access to biomedical data collected before, during and after spaceflight. These data are often irreplaceable and represent a major resource from the space program. For these data to be useful, however, they must be presented with enough supporting information, description and detail so that an interested scientist can understand how, when and why the data were collected. The goal of this contract was to provide a scientific consultant to the archival effort at the NASA-Johnson Space Center. This consultant (Jay C. Buckey, Jr., M.D.) is a scientist, who was a co-investigator on both the Spacelab Life Sciences-1 and Spacelab Life Sciences-2 flights. In addition he was an alternate payload specialist for the Spacelab Life Sciences-2 flight. In this role he trained on all the experiments on the flight and so was familiar with the protocols, hardware and goals of all the experiments on the flight. Many of these experiments were flown on both SLS-1 and SLS-2. This background was useful for the archive, since the first mission to be archived was Spacelab Life Sciences-1. Dr. Buckey worked directly with the archive effort to ensure that the parameters, scientific descriptions, protocols and data sets were accurate and useful.

Resources for Archives: Developing Collections, Constituents, Colleagues, and Capital

ERIC Educational Resources Information Center

Primer, Ben

2009-01-01

The essential element for archival success is to be found in the quality of management decisions made and public services provided. Archivists can develop first-class archives operations through understanding the organizational context; planning; hiring, retaining, and developing staff; meeting archival standards for storage and access; and…

Length Variation of Cag/Caa Trinucleotide Repeats in Natural Populations of Drosophila Melanogaster and Its Relation to the Recombination Rate

PubMed Central

Michalakis, Y.; Veuille, M.

1996-01-01

Eleven genes distributed along the Drosophila melanogaster chromosome 2 and showing exonic tandem repeats of glutamine codons (CAG or CAA) were surveyed for length variation in a sample of four European and African populations. Only one gene was monomorphic. Eight genes were polymorphic in all populations, with a total number of alleles varying between five and 12 for 120 chromosomes. The average heterozygozity per locus and population was 0.41. Selective neutrality in length variation could not be rejected under the assumptions of the infinite allele model. Significant population subdivision was found though no geographical pattern emerged, all populations being equally different. Significant linkage disequilibrium was found in four out of seven cases where the genetic distance between loci was <1 cM and was negligible when the distance was larger. There is evidence that these associations were established after the populations separated. An unexpected result was that variation at each locus was independent of the coefficient of exchange, although the latter ranged from zero to the relatively high value of 6.7%. This would indicate that background selection and selective hitchhiking, which are thought to affect levels of nucleotide substitution polymorphism, have no effect on trinucleotide repeat variation. PMID:8844158

The Alaska Arctic Vegetation Archive (AVA-AK)

DOE PAGES

Walker, Donald; Breen, Amy; Druckenmiller, Lisa; ...

2016-05-17

The Alaska Arctic Vegetation Archive (AVA-AK, GIVD-ID: NA-US-014) is a free, publically available database archive of vegetation-plot data from the Arctic tundra region of northern Alaska. The archive currently contains 24 datasets with 3,026 non-overlapping plots. Of these, 74% have geolocation data with 25-m or better precision. Species cover data and header data are stored in a Turboveg database. A standardized Pan Arctic Species List provides a consistent nomenclature for vascular plants, bryophytes, and lichens in the archive. A web-based online Alaska Arctic Geoecological Atlas (AGA-AK) allows viewing and downloading the species data in a variety of formats, and providesmore » access to a wide variety of ancillary data. We conducted a preliminary cluster analysis of the first 16 datasets (1,613 plots) to examine how the spectrum of derived clusters is related to the suite of datasets, habitat types, and environmental gradients. Here, we present the contents of the archive, assess its strengths and weaknesses, and provide three supplementary files that include the data dictionary, a list of habitat types, an overview of the datasets, and details of the cluster analysis.« less

NADIR: A Flexible Archiving System Current Development

NASA Astrophysics Data System (ADS)

Knapic, C.; De Marco, M.; Smareglia, R.; Molinaro, M.

2014-05-01

The New Archiving Distributed InfrastructuRe (NADIR) is under development at the Italian center for Astronomical Archives (IA2) to increase the performances of the current archival software tools at the data center. Traditional softwares usually offer simple and robust solutions to perform data archive and distribution but are awkward to adapt and reuse in projects that have different purposes. Data evolution in terms of data model, format, publication policy, version, and meta-data content are the main threats to re-usage. NADIR, using stable and mature framework features, answers those very challenging issues. Its main characteristics are a configuration database, a multi threading and multi language environment (C++, Java, Python), special features to guarantee high scalability, modularity, robustness, error tracking, and tools to monitor with confidence the status of each project at each archiving site. In this contribution, the development of the core components is presented, commenting also on some performance and innovative features (multi-cast and publisher-subscriber paradigms). NADIR is planned to be developed as simply as possible with default configurations for every project, first of all for LBT and other IA2 projects.

The Alaska Arctic Vegetation Archive (AVA-AK)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walker, Donald; Breen, Amy; Druckenmiller, Lisa

The Alaska Arctic Vegetation Archive (AVA-AK, GIVD-ID: NA-US-014) is a free, publically available database archive of vegetation-plot data from the Arctic tundra region of northern Alaska. The archive currently contains 24 datasets with 3,026 non-overlapping plots. Of these, 74% have geolocation data with 25-m or better precision. Species cover data and header data are stored in a Turboveg database. A standardized Pan Arctic Species List provides a consistent nomenclature for vascular plants, bryophytes, and lichens in the archive. A web-based online Alaska Arctic Geoecological Atlas (AGA-AK) allows viewing and downloading the species data in a variety of formats, and providesmore » access to a wide variety of ancillary data. We conducted a preliminary cluster analysis of the first 16 datasets (1,613 plots) to examine how the spectrum of derived clusters is related to the suite of datasets, habitat types, and environmental gradients. Here, we present the contents of the archive, assess its strengths and weaknesses, and provide three supplementary files that include the data dictionary, a list of habitat types, an overview of the datasets, and details of the cluster analysis.« less

ROSETTA: How to archive more than 10 years of mission

NASA Astrophysics Data System (ADS)

Barthelemy, Maud; Heather, D.; Grotheer, E.; Besse, S.; Andres, R.; Vallejo, F.; Barnes, T.; Kolokolova, L.; O'Rourke, L.; Fraga, D.; A'Hearn, M. F.; Martin, P.; Taylor, M. G. G. T.

2018-01-01

The Rosetta spacecraft was launched in 2004 and, after several planetary and two asteroid fly-bys, arrived at comet 67P/Churyumov-Gerasimenko in August 2014. After escorting the comet for two years and executing its scientific observations, the mission ended on 30 September 2016 through a touch down on the comet surface. This paper describes how the Planetary Science Archive (PSA) and the Planetary Data System - Small Bodies Node (PDS-SBN) worked with the Rosetta instrument teams to prepare the science data collected over the course of the Rosetta mission for inclusion in the science archive. As Rosetta is an international mission in collaboration between ESA and NASA, all science data from the mission are fully archived within both the PSA and the PDS. The Rosetta archiving process, supporting tools, archiving systems, and their evolution throughout the mission are described, along with a discussion of a number of the challenges faced during the Rosetta implementation. The paper then presents the current status of the archive for each of the science instruments, before looking to the improvements planned both for the archive itself and for the Rosetta data content. The lessons learned from the first 13 years of archiving on Rosetta are finally discussed with an aim to help future missions plan and implement their science archives.

A MYSQL-BASED DATA ARCHIVER: PRELIMINARY RESULTS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matthew Bickley; Christopher Slominski

2008-01-23

Following an evaluation of the archival requirements of the Jefferson Laboratory accelerator’s user community, a prototyping effort was executed to determine if an archiver based on MySQL had sufficient functionality to meet those requirements. This approach was chosen because an archiver based on a relational database enables the development effort to focus on data acquisition and management, letting the database take care of storage, indexing and data consistency. It was clear from the prototype effort that there were no performance impediments to successful implementation of a final system. With our performance concerns addressed, the lab undertook the design and developmentmore » of an operational system. The system is in its operational testing phase now. This paper discusses the archiver system requirements, some of the design choices and their rationale, and presents the acquisition, storage and retrieval performance.« less

76 FR 19147 - Advisory Committee on the Electronic Records Archives (ACERA)

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-06

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on the Electronic Records Archives... Electronic Records Archives (ACERA). The meeting has been consolidated into one day. This meeting will be... number of individuals planning to attend must be submitted to the Electronic Records Archives Program at...

The NAS Computational Aerosciences Archive

NASA Technical Reports Server (NTRS)

Miceli, Kristina D.; Globus, Al; Lasinski, T. A. (Technical Monitor)

1995-01-01

In order to further the state-of-the-art in computational aerosciences (CAS) technology, researchers must be able to gather and understand existing work in the field. One aspect of this information gathering is studying published work available in scientific journals and conference proceedings. However, current scientific publications are very limited in the type and amount of information that they can disseminate. Information is typically restricted to text, a few images, and a bibliography list. Additional information that might be useful to the researcher, such as additional visual results, referenced papers, and datasets, are not available. New forms of electronic publication, such as the World Wide Web (WWW), limit publication size only by available disk space and data transmission bandwidth, both of which are improving rapidly. The Numerical Aerodynamic Simulation (NAS) Systems Division at NASA Ames Research Center is in the process of creating an archive of CAS information on the WWW. This archive will be based on the large amount of information produced by researchers associated with the NAS facility. The archive will contain technical summaries and reports of research performed on NAS supercomputers, visual results (images, animations, visualization system scripts), datasets, and any other supporting meta-information. This information will be available via the WWW through the NAS homepage, located at http://www.nas.nasa.gov/, fully indexed for searching. The main components of the archive are technical summaries and reports, visual results, and datasets. Technical summaries are gathered every year by researchers who have been allotted resources on NAS supercomputers. These summaries, together with supporting visual results and references, are browsable by interested researchers. Referenced papers made available by researchers can be accessed through hypertext links. Technical reports are in-depth accounts of tools and applications research projects

A complete public archive for the Einstein IPC

NASA Technical Reports Server (NTRS)

Helfand, David J.

1993-01-01

This report documents progress made in the period 29 September 1992 and 28 September 1993, on the project described in our proposal 'A Complete Public Archive for the Einstein IPC,' which was approved under the Astrophysics Data Program last year. All of the principal first-year objectives were achieved and we expect to continue our efforts over the next two years toward the goal of transferring the entire activity to the HEASARC.

36 CFR 1253.2 - National Archives at College Park.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false National Archives at College Park. 1253.2 Section 1253.2 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS... College Park. (a) The National Archives at College Park is located at 8601 Adelphi Road, College Park, MD...

36 CFR 1253.2 - National Archives at College Park.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false National Archives at College Park. 1253.2 Section 1253.2 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS... Park, MD 20740-6001. Hours for the Research Center are posted at http://www.archives.gov. The phone...

36 CFR 1253.2 - National Archives at College Park.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false National Archives at College Park. 1253.2 Section 1253.2 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS... Park, MD 20740-6001. Hours for the Research Center are posted at http://www.archives.gov. The phone...

36 CFR 1253.2 - National Archives at College Park.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false National Archives at College Park. 1253.2 Section 1253.2 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS... Park, MD 20740-6001. Hours for the Research Center are posted at http://www.archives.gov. The phone...

Radiation Embrittlement Archive Project

DOE Office of Scientific and Technical Information (OSTI.GOV)

Klasky, Hilda B; Bass, Bennett Richard; Williams, Paul T

2013-01-01

The Radiation Embrittlement Archive Project (REAP), which is being conducted by the Probabilistic Integrity Safety Assessment (PISA) Program at Oak Ridge National Laboratory under funding from the U.S. Nuclear Regulatory Commission s (NRC) Office of Nuclear Regulatory Research, aims to provide an archival source of information about the effect of neutron radiation on the properties of reactor pressure vessel (RPV) steels. Specifically, this project is an effort to create an Internet-accessible RPV steel embrittlement database. The project s website, https://reap.ornl.gov, provides information in two forms: (1) a document archive with surveillance capsule(s) reports and related technical reports, in PDF format,more » for the 104 commercial nuclear power plants (NPPs) in the United States, with similar reports from other countries; and (2) a relational database archive with detailed information extracted from the reports. The REAP project focuses on data collected from surveillance capsule programs for light-water moderated, nuclear power reactor vessels operated in the United States, including data on Charpy V-notch energy testing results, tensile properties, composition, exposure temperatures, neutron flux (rate of irradiation damage), and fluence, (Fast Neutron Fluence a cumulative measure of irradiation for E>1 MeV). Additionally, REAP contains data from surveillance programs conducted in other countries. REAP is presently being extended to focus on embrittlement data analysis, as well. This paper summarizes the current status of the REAP database and highlights opportunities to access the data and to participate in the project.« less

BAO Plate Archive Project

NASA Astrophysics Data System (ADS)

Mickaelian, A. M.; Gigoyan, K. S.; Gyulzadyan, M. V.; Paronyan, G. M.; Abrahamyan, H. V.; Andreasyan, H. R.; Azatyan, N. M.; Kostandyan, G. R.; Samsonyan, A. L.; Mikayelyan, G. A.; Farmanyan, S. V.; Harutyunyan, V. L.

2017-12-01

We present the Byurakan Astrophysical Observatory (BAO) Plate Archive Project that is aimed at digitization, extraction and analysis of archival data and building an electronic database and interactive sky map. BAO Plate Archive consists of 37,500 photographic plates and films, obtained with 2.6m telescope, 1m and 0.5m Schmidt telescopes and other smaller ones during 1947-1991. The famous Markarian Survey (or the First Byurakan Survey, FBS) 2000 plates were digitized in 2002-2005 and the Digitized FBS (DFBS, www.aras.am/Dfbs/dfbs.html) was created. New science projects have been conducted based on this low-dispersion spectroscopic material. Several other smaller digitization projects have been carried out as well, such as part of Second Byurakan Survey (SBS) plates, photographic chain plates in Coma, where the blazar ON 231 is located and 2.6m film spectra of FBS Blue Stellar Objects. However, most of the plates and films are not digitized. In 2015, we have started a project on the whole BAO Plate Archive digitization, creation of electronic database and its scientific usage. Armenian Virtual Observatory (ArVO, www.aras.am/Arvo/arvo.htm) database will accommodate all new data. The project runs in collaboration with the Armenian Institute of Informatics and Automation Problems (IIAP) and will continues during 4 years in 2015-2018. The final result will be an Electronic Database and online Interactive Sky map to be used for further research projects. ArVO will provide all standards and tools for efficient usage of the scientific output and its integration in international databases.

Troubleshooting Public Data Archiving: Suggestions to Increase Participation

PubMed Central

Roche, Dominique G.; Lanfear, Robert; Binning, Sandra A.; Haff, Tonya M.; Schwanz, Lisa E.; Cain, Kristal E.; Kokko, Hanna; Jennions, Michael D.; Kruuk, Loeske E. B.

2014-01-01

An increasing number of publishers and funding agencies require public data archiving (PDA) in open-access databases. PDA has obvious group benefits for the scientific community, but many researchers are reluctant to share their data publicly because of real or perceived individual costs. Improving participation in PDA will require lowering costs and/or increasing benefits for primary data collectors. Small, simple changes can enhance existing measures to ensure that more scientific data are properly archived and made publicly available: (1) facilitate more flexible embargoes on archived data, (2) encourage communication between data generators and re-users, (3) disclose data re-use ethics, and (4) encourage increased recognition of publicly archived data. PMID:24492920

Guide to the Seattle Archives Branch.

ERIC Educational Resources Information Center

Hobbs, Richard, Comp.

The guide presents an overview of the textual and microfilmed records located at the Seattle Branch of the National Archives of the United States. Established in 1969, the Seattle Archives Branch is one of 11 branches which preserve and make available for research those U.S. Government records of permanent value created and maintained by Federal…

77 FR 36297 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-18

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Agency Information Collection Activities: Proposed Collection; Comment Request AGENCY: National Archives and Records Administration (NARA). ACTION: Notice... Reduction Act Comments (NHP), Room 4400, National Archives and Records Administration, 8601 Adelphi Rd...

78 FR 78401 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-26

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION [NARA-2014-012] Agency Information Collection Activities: Proposed Collection; Comment Request AGENCY: National Archives and Records Administration (NARA... biomedical statistical research in archival records containing highly personal information. The second is...

76 FR 72449 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-23

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Agency Information Collection Activities: Proposed Collection; Comment Request AGENCY: National Archives and Records Administration (NARA). ACTION: Notice... Reduction Act Comments (ISP), Room 4400, National Archives and Records Administration, 8601 Adelphi Rd...

The proactive historian: Methodological opportunities presented by the new archives documenting genomics.

PubMed

García-Sancho, Miguel

2016-02-01

In this paper, I propose a strategy for navigating newly available archives in the study of late-twentieth century genomics. I demonstrate that the alleged 'explosion of data' characteristic of genomics-and of contemporary science in general-is not a new problem and that historians of earlier periods have dealt with information overload by relying on the 'perspective of time': the filtering effect the passage of time naturally exerts on both sources and memories. I argue that this reliance on the selective capacity of time results in inheriting archives curated by others and, consequently, poses the risk of reifying ahistorical scientific discourses. Through a preliminary examination of archives documenting early attempts at mapping and sequencing the human genome, I propose an alternative approach, in which historians proactively problematize and improve available sources. This approach provides historians with a voice in the socio-political management of scientific heritage and advances methodological innovations in the use of oral histories. It also provides a narrative framework in which to address big science initiatives by following second order administrators, rather than individual scientists. The new genomic archives thus represent an opportunity for historians to take an active role in current debates concerning 'big data' and critically embed the humanities in pressing global problems. Copyright © 2015 Elsevier Ltd. All rights reserved.

75 FR 69474 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-12

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Agency Information Collection Activities: Proposed Collection; Comment Request AGENCY: National Archives and Records Administration (NARA). ACTION: Notice... research in archival records containing highly personal information. The second is an application that is...

75 FR 66802 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-29

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Agency Information Collection Activities: Proposed Collection; Comment Request AGENCY: National Archives and Records Administration (NARA). ACTION: Notice...: NATF 81, National Archives Order for Copies of Ship Passenger Arrival Records; NATF 82, National...

The Post-Soviet Archives: Organization, Access, and Declassification

DTIC Science & Technology

1993-01-01

attempting to place these files under Poskeirkhlv but has had limited success . The successors to the 503-the Ninistry of Security and the Foreign...their transfer to Roakomazkbiv. Pikhoia was able to take over these archives with some success ; yet, comp~lete control over the RO= archives has alluded...key 1Mironenko interview, May 27, 1992. - 20 - players are involved in the management of the Russian Presidential Archive. First, the director of the

PH5 for integrating and archiving different data types

NASA Astrophysics Data System (ADS)

Azevedo, Steve; Hess, Derick; Beaudoin, Bruce

2016-04-01

PH5 is IRIS PASSCAL's file organization of HDF5 used for seismic data. The extensibility and portability of HDF5 allows the PH5 format to evolve and operate on a variety of platforms and interfaces. To make PH5 even more flexible, the seismic metadata is separated from the time series data in order to achieve gains in performance as well as ease of use and to simplify user interaction. This separation affords easy updates to metadata after the data are archived without having to access waveform data. To date, PH5 is currently used for integrating and archiving active source, passive source, and onshore-offshore seismic data sets with the IRIS Data Management Center (DMC). Active development to make PH5 fully compatible with FDSN web services and deliver StationXML is near completion. We are also exploring the feasibility of utilizing QuakeML for active seismic source representation. The PH5 software suite, PIC KITCHEN, comprises in-field tools that include data ingestion (e.g. RefTek format, SEG-Y, and SEG-D), meta-data management tools including QC, and a waveform review tool. These tools enable building archive ready data in-field during active source experiments greatly decreasing the time to produce research ready data sets. Once archived, our online request page generates a unique web form and pre-populates much of it based on the metadata provided to it from the PH5 file. The data requester then can intuitively select the extraction parameters as well as data subsets they wish to receive (current output formats include SEG-Y, SAC, mseed). The web interface then passes this on to the PH5 processing tools to generate the requested seismic data, and e-mail the requester a link to the data set automatically as soon as the data are ready. PH5 file organization was originally designed to hold seismic time series data and meta-data from controlled source experiments using RefTek data loggers. The flexibility of HDF5 has enabled us to extend the use of PH5 in several

Recommendations for a service framework to access astronomical archives

NASA Technical Reports Server (NTRS)

Travisano, J. J.; Pollizzi, J.

1992-01-01

There are a large number of astronomical archives and catalogs on-line for network access, with many different user interfaces and features. Some systems are moving towards distributed access, supplying users with client software for their home sites which connects to servers at the archive site. Many of the issues involved in defining a standard framework of services that archive/catalog suppliers can use to achieve a basic level of interoperability are described. Such a framework would simplify the development of client and server programs to access the wide variety of astronomical archive systems. The primary services that are supplied by current systems include: catalog browsing, dataset retrieval, name resolution, and data analysis. The following issues (and probably more) need to be considered in establishing a standard set of client/server interfaces and protocols: Archive Access - dataset retrieval, delivery, file formats, data browsing, analysis, etc.; Catalog Access - database management systems, query languages, data formats, synchronous/asynchronous mode of operation, etc.; Interoperability - transaction/message protocols, distributed processing mechanisms (DCE, ONC/SunRPC, etc), networking protocols, etc.; Security - user registration, authorization/authentication mechanisms, etc.; Service Directory - service registration, lookup, port/task mapping, parameters, etc.; Software - public vs proprietary, client/server software, standard interfaces to client/server functions, software distribution, operating system portability, data portability, etc. Several archive/catalog groups, notably the Astrophysics Data System (ADS), are already working in many of these areas. In the process of developing StarView, which is the user interface to the Space Telescope Data Archive and Distribution Service (ST-DADS), these issues and the work of others were analyzed. A framework of standard interfaces for accessing services on any archive system which would benefit

Fermilab History and Archives Project | Announcement of Renaming NAL

Science.gov Websites

Archives Project Home About the Archives History and Archives Online Request Contact Us History & Fermi Laboratory In 1972 Enrico Fermi, Nobel Laureate Physicist Return to the Wilson Years NAL TO BECOME ENRICO FERMI LABORATORY IN 1972 Dr. Glenn T. Seaborg, Chairman of the Atomic Energy Commission, announced

The challenge of archiving and preserving remotely sensed data

USGS Publications Warehouse

Faundeen, John L.

2003-01-01

Few would question the need to archive the scientific and technical (S&T) data generated by researchers. At a minimum, the data are needed for change analysis. Likewise, most people would value efforts to ensure the preservation of the archived S&T data. Future generations will use analysis techniques not even considered today. Until recently, archiving and preserving these data were usually accomplished within existing infrastructures and budgets. As the volume of archived data increases, however, organizations charged with archiving S&T data will be increasingly challenged (U.S. General Accounting Office, 2002). The U.S. Geological Survey has had experience in this area and has developed strategies to deal with the mountain of land remote sensing data currently being managed and the tidal wave of expected new data. The Agency has dealt with archiving issues, such as selection criteria, purging, advisory panels, and data access, and has met with preservation challenges involving photographic and digital media. That experience has allowed the USGS to develop management approaches, which this paper outlines.

GLAS Long-Term Archive: Preservation and Stewardship for a Vital Earth Observing Mission

NASA Astrophysics Data System (ADS)

Fowler, D. K.; Moses, J. F.; Zwally, J.; Schutz, B. E.; Hancock, D.; McAllister, M.; Webster, D.; Bond, C.

2012-12-01

Data Stewardship, preservation, and reproducibility are fast becoming principal parts of a data manager's work. In an era of distributed data and information systems, it is of vital importance that organizations make a commitment to both current and long-term goals of data management and the preservation of scientific data. Satellite missions and instruments go through a lifecycle that involves pre-launch calibration, on-orbit data acquisition and product generation, and final reprocessing. Data products and descriptions flow to the archives for distribution on a regular basis during the active part of the mission. However there is additional information from the product generation and science teams needed to ensure the observations will be useful for long term climate studies. Examples include ancillary input datasets, product generation software, and production history as developed by the team during the course of product generation. These data and information will need to be archived after product data processing is completed. NASA has developed a set of Earth science data and information content requirements for long term preservation that is being used for all the EOS missions as they come to completion. Since the ICESat/GLAS mission was one of the first to end, NASA and NSIDC, in collaboration with the science team, are collecting data, software, and documentation, preparing for long-term support of the ICESat mission. For a long-term archive, it is imperative to preserve sufficient information about how products were prepared in order to ensure future researchers that the scientific results are accurate, understandable, and useable. Our experience suggests data centers know what to preserve in most cases. That is, the processing algorithms along with the Level 0 or Level 1a input and ancillary products used to create the higher-level products will be archived and made available to users. In other cases, such as pre-launch, calibration/validation, and test

COMBINE archive and OMEX format: one file to share all information to reproduce a modeling project.

PubMed

Bergmann, Frank T; Adams, Richard; Moodie, Stuart; Cooper, Jonathan; Glont, Mihai; Golebiewski, Martin; Hucka, Michael; Laibe, Camille; Miller, Andrew K; Nickerson, David P; Olivier, Brett G; Rodriguez, Nicolas; Sauro, Herbert M; Scharm, Martin; Soiland-Reyes, Stian; Waltemath, Dagmar; Yvon, Florent; Le Novère, Nicolas

2014-12-14

With the ever increasing use of computational models in the biosciences, the need to share models and reproduce the results of published studies efficiently and easily is becoming more important. To this end, various standards have been proposed that can be used to describe models, simulations, data or other essential information in a consistent fashion. These constitute various separate components required to reproduce a given published scientific result. We describe the Open Modeling EXchange format (OMEX). Together with the use of other standard formats from the Computational Modeling in Biology Network (COMBINE), OMEX is the basis of the COMBINE Archive, a single file that supports the exchange of all the information necessary for a modeling and simulation experiment in biology. An OMEX file is a ZIP container that includes a manifest file, listing the content of the archive, an optional metadata file adding information about the archive and its content, and the files describing the model. The content of a COMBINE Archive consists of files encoded in COMBINE standards whenever possible, but may include additional files defined by an Internet Media Type. Several tools that support the COMBINE Archive are available, either as independent libraries or embedded in modeling software. The COMBINE Archive facilitates the reproduction of modeling and simulation experiments in biology by embedding all the relevant information in one file. Having all the information stored and exchanged at once also helps in building activity logs and audit trails. We anticipate that the COMBINE Archive will become a significant help for modellers, as the domain moves to larger, more complex experiments such as multi-scale models of organs, digital organisms, and bioengineering.

Interoperability at ESA Heliophysics Science Archives: IVOA, HAPI and other implementations

NASA Astrophysics Data System (ADS)

Martinez-Garcia, B.; Cook, J. P.; Perez, H.; Fernandez, M.; De Teodoro, P.; Osuna, P.; Arnaud, M.; Arviset, C.

2017-12-01

The data of ESA heliophysics science missions are preserved at the ESAC Science Data Centre (ESDC). The ESDC aims for the long term preservation of those data, which includes missions such as Ulysses, Soho, Proba-2, Cluster, Double Star, and in the future, Solar Orbiter. Scientists have access to these data through web services, command line and graphical user interfaces for each of the corresponding science mission archives. The International Virtual Observatory Alliance (IVOA) provides technical standards that allow interoperability among different systems that implement them. By adopting some IVOA standards, the ESA heliophysics archives are able to share their data with those tools and services that are VO-compatible. Implementation of those standards can be found in the existing archives: Ulysses Final Archive (UFA) and Soho Science Archive (SSA). They already make use of VOTable format definition and Simple Application Messaging Protocol (SAMP). For re-engineered or new archives, the implementation of services through Table Access Protocol (TAP) or Universal Worker Service (UWS) will leverage this interoperability. This will be the case for the Proba-2 Science Archive (P2SA) and the Solar Orbiter Archive (SOAR). We present here which IVOA standards were already used by the ESA Heliophysics archives in the past and the work on-going.

[Psychiatric Archives: Archive for which History? The Writings and Drawings of René L.

PubMed

Artières, Philippe

The archives of the psychiatric institutions are often mobilized to investigate the history of the treatment of mental disorders and its modalities in our societies. From a patient's record, interned in the Hôpital du Bon Sauveur in the department of Manche in France in 1963, this article shows how these archives are part of writing a different story that of decolonization and particularly the independence of Algeria and the end of French colonization. In particular, studied the drawings by this patient and the way it reflects the collective history.

Planetary Data Archiving Plan at JAXA

NASA Astrophysics Data System (ADS)

Shinohara, Iku; Kasaba, Yasumasa; Yamamoto, Yukio; Abe, Masanao; Okada, Tatsuaki; Imamura, Takeshi; Sobue, Shinichi; Takashima, Takeshi; Terazono, Jun-Ya

After the successful rendezvous of Hayabusa with the small-body planet Itokawa, and the successful launch of Kaguya to the moon, Japanese planetary community has gotten their own and full-scale data. However, at this moment, these datasets are only available from the data sites managed by each mission team. The databases are individually constructed in the different formats, and the user interface of these data sites is not compatible with foreign databases. To improve the usability of the planetary archives at JAXA and to enable the international data exchange smooth, we are investigating to make a new planetary database. Within a coming decade, Japan will have fruitful datasets in the planetary science field, Venus (Planet-C), Mercury (BepiColombo), and several missions in planning phase (small-bodies). In order to strongly assist the international scientific collaboration using these mission archive data, the planned planetary data archive at JAXA should be managed in an unified manner and the database should be constructed in the international planetary database standard style. In this presentation, we will show the current status and future plans of the planetary data archiving at JAXA.

LBT Distributed Archive: Status and Features

NASA Astrophysics Data System (ADS)

Knapic, C.; Smareglia, R.; Thompson, D.; Grede, G.

2011-07-01

After the first release of the LBT Distributed Archive, this successful collaboration is continuing within the LBT corporation. The IA2 (Italian Center for Astronomical Archive) team had updated the LBT DA with new features in order to facilitate user data retrieval while abiding by VO standards. To facilitate the integration of data from any new instruments, we have migrated to a new database, developed new data distribution software, and enhanced features in the LBT User Interface. The DBMS engine has been changed to MySQL. Consequently, the data handling software now uses java thread technology to update and synchronize the main storage archives on Mt. Graham and in Tucson, as well as archives in Trieste and Heidelberg, with all metadata and proprietary data. The LBT UI has been updated with additional features allowing users to search by instrument and some of the more important characteristics of the images. Finally, instead of a simple cone search service over all LBT image data, new instrument specific SIAP and cone search services have been developed. They will be published in the IVOA framework later this fall.

76 FR 15349 - Advisory Committee on the Electronic Records Archives (ACERA); Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-21

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on the Electronic Records Archives (ACERA); Meeting AGENCY: National Archives and Records Administration. ACTION: Notice of Meeting. SUMMARY... Archives and Records Administration (NARA) announces a meeting of the Advisory Committee on the Electronic...

[The contribution of the Archive of the Military Medical Museum in summarizing the experience of the Great Patriotic War].

PubMed

Budko, A A; Gribovskaya, G A

2015-06-01

During 70 years of existence of the Military Medical Museum one of its main goals was to create an archive of military medical documents, the formation of his ideology and collecting funds, saving and promotion of unique materials related to the history of Russia, feat of arms Defenders of the Fatherland in the wars of the XX century. Creating a military medical museum archive was conceived in the beginning of the Great Patriotic War by leading figures of the military medicine--E.I.Smirnov, S.M.Bagdasaryan, V.N.Shevkunenko, A.N.Maksimenkov, who offered to collect all materials about the work of physicians at the front and in the rear, to consider the archive as a base for scientific works on the history of the military health care. Today the archive was removed from the Army Medical Museum and now it is a branch of the Central Archive of the Ministry of Defence of the Russian Federation (military medical records). His staff keeps the traditions established by predecessors and use in their activities a wealth of experience and background research.

PACS archive upgrade and data migration: clinical experiences

NASA Astrophysics Data System (ADS)

Liu, Brent J.; Documet, Luis; Sarti, Dennis A.; Huang, H. K.; Donnelly, John

2002-05-01

Saint John's Health Center PACS data volumes have increased dramatically since the hospital became filmless in April of 1999. This is due in part of continuous image accumulation, and the integration of a new multi-slice detector CT scanner into PACS. The original PACS archive would not be able to handle the distribution and archiving load and capacity in the near future. Furthermore, there is no secondary copy backup of all the archived PACS image data for disaster recovery purposes. The purpose of this paper is to present a clinical and technical process template to upgrade and expand the PACS archive, migrate existing PACs image data to the new archive, and provide a back-up and disaster recovery function not currently available. Discussion of the technical and clinical pitfalls and challenges involved in this process will be presented as well. The server hardware configuration was upgraded and a secondary backup implemented for disaster recovery. The upgrade includes new software versions, database reconfiguration, and installation of a new tape jukebox to replace the current MOD jukebox. Upon completion, all PACS image data from the original MOD jukebox was migrated to the new tape jukebox and verified. The migration was performed during clinical operation continuously in the background. Once the data migration was completed the MOD jukebox was removed. All newly acquired PACS exams are now archived to the new tape jukebox. All PACs image data residing on the original MOD jukebox have been successfully migrated into the new archive. In addition, a secondary backup of all PACS image data has been implemented for disaster recovery and has been verified using disaster scenario testing. No PACS image data was lost during the entire process and there was very little clinical impact during the entire upgrade and data migration. Some of the pitfalls and challenges during this upgrade process included hardware reconfiguration for the original archive server, clinical

Three Good Reasons for Celebrating at the ESO/ST-ECF Science Archive Facility

NASA Astrophysics Data System (ADS)

2000-12-01

Great Demand for Data from New "Virtual Observatory" Summary Due to a happy coincidence, the ESO/ST-ECF Science Archive Facility is celebrating three different milestones at the same time: * its 10th anniversary since the establishment in 1991 * the 10,000th request for data , and * the signing-up of active user number 2000 . This Archive contains over 8 Terabytes (1 Terabyte = 1 million million bytes) of valuable observational data from the NASA/ESA Hubble Space Telescope (HST), the ESO Very Large Telescope (VLT) and other ESO telescopes . Its success paves the way for the establishment of "Virtual Observatories" from which first-class data can be obtained by astronomers all over the world. This greatly enhances the opportunities for more (young) scientists to participate in front-line research. PR Photo 34/00 : Front-page of a new brochure, describing the ESO/ST-ECF Science Archive Facility. Just 10 years ago, on the 1st of January 1991, the ESO/ST-ECF (European Southern Observatory/Space Telescope-European Coordinating Facility) Science Archive Facility opened. It has since served the astronomical community with gigabyte after gigabyte of high-quality astronomical data from some of the world's leading telescopes. The Archive, which is located in Garching, just outside Munich (Germany), contains data from the 2.4-m NASA/ESA Hubble Space Telescope , as well as from several ESO telescopes: the four 8.2-m Unit Telescopes of the Very Large Telescope (VLT) at the Paranal Observatory , and the 3.5-m New Technology Telescope (NTT) , the 3.6-m telescope and the MPG/ESO 2.2-m telescope at La Silla. The Archive is a continuously developing project - in terms of amounts of data stored, the number of users and in particular because of the current dramatic development of innovative techniques for data handling and storage. In the year 2000 more than 2 Terabytes (2000 Gigabytes) of data were distributed to users worldwide. The archiving of VLT data has been described in ESO PR

PRESENTATION TYPE: Round Table Discussion (80 minutes) TITLE: Unlocking the ‘Omics Archive: Enabling Toxicogenomic/Proteomic Investigation from Archival Samples

EPA Science Inventory

Formalin fixation and paraffin embedding (FFPE) is a cross-industry gold standard for preparing nonclinical and clinical samples for histopathological assessment which preserves tissue architecture and enables storage of tissue in archival banks. These archival banks are an untap...

36 CFR § 1253.1 - National Archives Building.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., DC 20408. Hours for the Research Center and the Central Research Room are posted at http://www.archives.gov. The exhibit areas' hours of operation are also posted at http://www.archives.gov. Last...

NASA's astrophysics archives at the National Space Science Data Center

NASA Technical Reports Server (NTRS)

Vansteenberg, M. E.

1992-01-01

NASA maintains an archive facility for Astronomical Science data collected from NASA's missions at the National Space Science Data Center (NSSDC) at Goddard Space Flight Center. This archive was created to insure the science data collected by NASA would be preserved and useable in the future by the science community. Through 25 years of operation there are many lessons learned, from data collection procedures, archive preservation methods, and distribution to the community. This document presents some of these more important lessons, for example: KISS (Keep It Simple, Stupid) in system development. Also addressed are some of the myths of archiving, such as 'scientists always know everything about everything', or 'it cannot possibly be that hard, after all simple data tech's do it'. There are indeed good reasons that a proper archive capability is needed by the astronomical community, the important question is how to use the existing expertise as well as the new innovative ideas to do the best job archiving this valuable science data.

Correlation of Serum and Dried Blood Spot Results for Quantitation of Schistosoma Circulating Anodic Antigen: a Proof of Principle

PubMed Central

Downs, Jennifer A.; Corstjens, Paul L.A.M.; Mngara, Julius; Lutonja, Peter; Isingo, Raphael; Urassa, Mark; Kornelis, Dieuwke; van Dam, Govert J.

2015-01-01

Circulating Anodic Antigen (CAA) testing is a powerful, increasingly-used tool for diagnosis of active schistosome infection. We sought to determine the feasibility and reliability of measuring CAA in blood spots collected on Whatman 903 Protein Saver cards, which are the predominant filter papers used worldwide for dried blood spot (DBS) research and clinical care. CAA was eluted from blood spots collected from 19 individuals onto Whatman 903 cards in Mwanza, Tanzania, and the assay was optimized to achieve CAA ratios comparable to those obtained from the spots’ corresponding serum samples. The optimized assay was then used to determine the correlation of serum samples (n=16) with DBS from cards that had been stored for 8 years at ambient temperature.Using a DBS volume equivalent to approximately four times the quantity of serum, CAA testing in DBS had a sensitivity of 76% and a specificity of 79% compared to CAA testing in serum. CAA testing was reliable in samples eluted from Whatman 903 cards that had been stored for 8 years at ambient temperature. The overall kappa coefficient was 0.53 (standard error 0.17, p<0.001). We conclude that CAA can be reliably and accurately measured in DBS collected onto the filter paper that is most commonly used for clinical care and research, and that can be stored for prolonged periods of time. This finding opens new avenues for future work among more than 700 million individuals living in areas worldwide in which schistosomes are endemic. PMID:26149541

Shoichi Sakata: His Life and Physics ---Collections of Materials in Sakata Memorial Archival Library---

NASA Astrophysics Data System (ADS)

Tanabashi, M.

Shoichi Sakata and his Nagoya School made a lot of important achievements at the predawn of the particle physics revolution. The ``two-meson'' theory (introduction of the second generation leptons), the ``C-meson theory'' (a theory which inspired Tomonaga's renormalization theory), the ``Sakata model'' (a precursor to the quark model), and the ``Maki-Nakagawa-Sakata'' theory on the neutrino mixings are among them. These outputs are now regarded as essential ingredients in modern particle physics. Sakata also took his leadership in setting up democratic administration system in his theoretical particle physics group (E-ken). It was this democratic atmosphere in which many excellent physicists were brought up as Sakata's diciples. In this talk, I introduce Sakata and his achievements in physics, showing various materials archived in the Sakata Memorial Archival Library (SMAL), an archival repository of primary material showing Sakata's activities. These SMAL documents vividly show Sakata's way of thinking in his approach to the new physics.

Remediation of the protein data bank archive.

PubMed

Henrick, Kim; Feng, Zukang; Bluhm, Wolfgang F; Dimitropoulos, Dimitris; Doreleijers, Jurgen F; Dutta, Shuchismita; Flippen-Anderson, Judith L; Ionides, John; Kamada, Chisa; Krissinel, Eugene; Lawson, Catherine L; Markley, John L; Nakamura, Haruki; Newman, Richard; Shimizu, Yukiko; Swaminathan, Jawahar; Velankar, Sameer; Ory, Jeramia; Ulrich, Eldon L; Vranken, Wim; Westbrook, John; Yamashita, Reiko; Yang, Huanwang; Young, Jasmine; Yousufuddin, Muhammed; Berman, Helen M

2008-01-01

The Worldwide Protein Data Bank (wwPDB; wwpdb.org) is the international collaboration that manages the deposition, processing and distribution of the PDB archive. The online PDB archive at ftp://ftp.wwpdb.org is the repository for the coordinates and related information for more than 47 000 structures, including proteins, nucleic acids and large macromolecular complexes that have been determined using X-ray crystallography, NMR and electron microscopy techniques. The members of the wwPDB-RCSB PDB (USA), MSD-EBI (Europe), PDBj (Japan) and BMRB (USA)-have remediated this archive to address inconsistencies that have been introduced over the years. The scope and methods used in this project are presented.

Long-term archives reveal shifting extinction selectivity in China's postglacial mammal fauna

PubMed Central

Crees, Jennifer J.; Li, Zhipeng; Bielby, Jon; Yuan, Jing

2017-01-01

Ecosystems have been modified by human activities for millennia, and insights about ecology and extinction risk based only on recent data are likely to be both incomplete and biased. We synthesize multiple long-term archives (over 250 archaeological and palaeontological sites dating from the early Holocene to the Ming Dynasty and over 4400 historical records) to reconstruct the spatio-temporal dynamics of Holocene–modern range change across China, a megadiverse country experiencing extensive current-day biodiversity loss, for 34 mammal species over three successive postglacial time intervals. Our combined zooarchaeological, palaeontological, historical and current-day datasets reveal that both phylogenetic and spatial patterns of extinction selectivity have varied through time in China, probably in response both to cumulative anthropogenic impacts (an ‘extinction filter’ associated with vulnerable species and accessible landscapes being affected earlier by human activities) and also to quantitative and qualitative changes in regional pressures. China has experienced few postglacial global species-level mammal extinctions, and most species retain over 50% of their maximum estimated Holocene range despite millennia of increasing regional human pressures, suggesting that the potential still exists for successful species conservation and ecosystem restoration. Data from long-term archives also demonstrate that herbivores have experienced more historical extinctions in China, and carnivores have until recently displayed greater resilience. Accurate assessment of patterns of biodiversity loss and the likely predictive power of current-day correlates of faunal vulnerability and resilience is dependent upon novel perspectives provided by long-term archives. PMID:29167363

Latin American Archives.

ERIC Educational Resources Information Center

Belsunce, Cesar A. Garcia

1983-01-01

Examination of the situation of archives in four Latin American countries--Argentina, Brazil, Colombia, and Costa Rica--highlights national systems, buildings, staff, processing of documents, accessibility and services to the public and publications and extension services. (EJS)

Desired Precision in Multi-Objective Optimization: Epsilon Archiving or Rounding Objectives?

NASA Astrophysics Data System (ADS)

Asadzadeh, M.; Sahraei, S.

2016-12-01

Multi-objective optimization (MO) aids in supporting the decision making process in water resources engineering and design problems. One of the main goals of solving a MO problem is to archive a set of solutions that is well-distributed across a wide range of all the design objectives. Modern MO algorithms use the epsilon dominance concept to define a mesh with pre-defined grid-cell size (often called epsilon) in the objective space and archive at most one solution at each grid-cell. Epsilon can be set to the desired precision level of each objective function to make sure that the difference between each pair of archived solutions is meaningful. This epsilon archiving process is computationally expensive in problems that have quick-to-evaluate objective functions. This research explores the applicability of a similar but computationally more efficient approach to respect the desired precision level of all objectives in the solution archiving process. In this alternative approach each objective function is rounded to the desired precision level before comparing any new solution to the set of archived solutions that already have rounded objective function values. This alternative solution archiving approach is compared to the epsilon archiving approach in terms of efficiency and quality of archived solutions for solving mathematical test problems and hydrologic model calibration problems.

Archived Data User Service self evaluation report : FAST

DOT National Transportation Integrated Search

2000-11-01

The Archived Data User Service (ADUS) is a recent addition to the National Intelligent Transportation System (ITS) Architecture. This user service required ITS system to have the capability to receive, collect and archive ITS-generated operational...

An Introduction to Archival Automation: A RAMP Study with Guidelines.

ERIC Educational Resources Information Center

Cook, Michael

Developed under a contract with the International Council on Archives, these guidelines are designed to emphasize the role of automation techniques in archives and records services, provide an indication of existing computer systems used in different archives services and of specific computer applications at various stages of archives…

75 FR 12573 - Advisory Committee on the Electronic Records Archives (ACERA)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-16

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on the Electronic Records Archives (ACERA) AGENCY: National Archives and Records Administration. ACTION: Notice of meeting. SUMMARY: In... and Records Administration (NARA) announces a [[Page 12574

Better Living Through Metadata: Examining Archive Usage

NASA Astrophysics Data System (ADS)

Becker, G.; Winkelman, S.; Rots, A.

2013-10-01

The primary purpose of an observatory's archive is to provide access to the data through various interfaces. User interactions with the archive are recorded in server logs, which can be used to answer basic questions like: Who has downloaded dataset X? When did she do this? Which tools did she use? The answers to questions like these fill in patterns of data access (e.g., how many times dataset X has been downloaded in the past three years). Analysis of server logs provides metrics of archive usage and provides feedback on interface use which can be used to guide future interface development. The Chandra X-ray Observatory is fortunate in that a database to track data access and downloads has been continuously recording such transactions for years; however, it is overdue for an update. We will detail changes we hope to effect and the differences the changes may make to our usage metadata picture. We plan to gather more information about the geographic location of users without compromising privacy; create improved archive statistics; and track and assess the impact of web “crawlers” and other scripted access methods on the archive. With the improvements to our download tracking we hope to gain a better understanding of the dissemination of Chandra's data; how effectively it is being done; and perhaps discover ideas for new services.

Studying The Spectral Shape And The X-ray/uv Variability Of Active Galactic Nuclei With Data From Swift And Xmm Archives

NASA Astrophysics Data System (ADS)

Turriziani, Sara

2011-01-01

Many efforts have been made in understanding the underlying origin of variability in Active Galactic Nuclei (AGN), but at present they could give still no conclusive answers. Since a deeper knowledge of variability will enable to understand better the accretion process onto supermassive black holes, I built the first ensemble struction function analysis of the X-ray variability of samples of quasars with data from Swift and XMM-Newton archives in order to study the average properties of their variability. Moreover, it is known that UV and X-ray luminosities of quasars are correlated and recent studies quantified this relation across 5 orders of magnitude. In this context, I presents results on the X-ray/UV ratio from simultaneous observations in UV and X-ray bands of a sample of quasars with data from XMM-Newton archive. Lastly, I will present a complete sample of Swift/SDSS faint blazars and other non-thermal dominated AGNs. I used this sample to calculate the general statistical properties of faint blazars and radio galaxies and in particular their Radio LogN-LogS with fluxes down to 10 mJy, in order to gain knowledge on the contribution to Cosmic Microwave Background (CMB) and gamma-ray background radiation from the faint tail of the radio population. I acknowledge financial support through Grant ASI I/088/06/0.

Clinical experiences with an ASP model backup archive for PACS images

NASA Astrophysics Data System (ADS)

Liu, Brent J.; Cao, Fei; Documet, Luis; Huang, H. K.; Muldoon, Jean

2003-05-01

Last year we presented a Fault-Tolerant Backup Archive using an Application Service Provider (ASP) model for disaster recovery. The purpose of this paper is to update and provide clinical experiences related towards implementing the ASP model archive solution for short-term backup of clinical PACS image data as well as possible applications other than disaster recovery. The ASP backup archive provides instantaneous, automatic backup of acquired PACS image data and instantaneous recovery of stored PACS image data all at a low operational cost and with little human intervention. This solution can be used for a variety of scheduled and unscheduled downtimes that occur on the main PACS archive. A backup archive server with hierarchical storage was implemented offsite from the main PACS archive location. Clinical data from a hospital PACS is sent to this ASP storage server in parallel to the exams being archived in the main server. Initially, connectivity between the main archive and the ASP storage server is established via a T-1 connection. In the future, other more cost-effective means of connectivity will be researched such as the Internet 2. We have integrated the ASP model backup archive with a clinical PACS at Saint John's Health Center and has been operational for over 6 months. Pitfalls encountered during integration with a live clinical PACS and the impact to clinical workflow will be discussed. In addition, estimations of the cost of establishing such a solution as well as the cost charged to the users will be included. Clinical downtime scenarios, such as a scheduled mandatory downtime and an unscheduled downtime due to a disaster event to the main archive, were simulated and the PACS exams were sent successfully from the offsite ASP storage server back to the hospital PACS in less than 1 day. The ASP backup archive was able to recover PACS image data for comparison studies with no complex operational procedures. Furthermore, no image data loss was

Archival of Amateur Observations in Support to ESA/Rosetta Mission

NASA Astrophysics Data System (ADS)

Shirinian, R.; Yanamandra-Fisher, P. A.; Buratti, B. J.

2016-12-01

The European Space Agency's Rosetta mission to comet 67P/Churyumov-Gerasimenko (CG) has included a global ground-based observing campaign consisting of both professional and amateur observers. While professional observers have access to world class observatories with multi-spectral instruments, amateur observers use smaller aperture telescopes that mainly cover the optical spectrum. Amateur observers however, have the advantage of being able to observe as needed since their time is not competed by other observers as it is in professional facilities. This allows amateurs to create a temporal baseline of observations throughout a mission to complement professional observations with context. The Rosetta mission has had an active amateur observer campaign for over 2 years, from January 2014 to August 2016 and has nearly 150 active observers from around the globe. As the Rosetta mission and its observer campaign come to an end in September 2016, an important goal of the project is the collection and archival of the amateur observational data. The ESA's Planetary Science Archive (PSA) has created a unique system that provides firewalled user-specific directories for amateur observers to upload and archive their data, allowing professionals and amateurs to crowdsource data for future science analyses. Possible future science products could include analysis of luminosity, dust cover, position angle, and tail length, all of which can be analyzed over time due to the consistent amateur data taken for over two years. A challenge for the project is that amateur observers have varying amounts of data, ranging from a few megabytes to several gigabytes. Our project addresses the retrieval of amateur observations, renaming, reformatting, and upload to the PSA. The final steps of the archival of amateur observations are the quality check of the data, some of the possible analyses, and identification of data that can be integrated with professional data analysis. The unique

A Structure Standard for Archival Context: EAC-CPF Is Here

ERIC Educational Resources Information Center

Dryden, Jean

2010-01-01

The archival community's new descriptive standard, "Encoded Archival Context" for Corporate Bodies, Persons, and Families (EAC-CPF), supports the sharing of descriptions of records creators and is a significant addition to the suite of standards for archival description. EAC-CPF is a data structure standard similar to its older sibling EAD…

Improving Internet Archive Service through Proxy Cache.

ERIC Educational Resources Information Center

Yu, Hsiang-Fu; Chen, Yi-Ming; Wang, Shih-Yong; Tseng, Li-Ming

2003-01-01

Discusses file transfer protocol (FTP) servers for downloading archives (files with particular file extensions), and the change to HTTP (Hypertext transfer protocol) with increased Web use. Topics include the Archie server; proxy cache servers; and how to improve the hit rate of archives by a combination of caching and better searching mechanisms.…

76 FR 4737 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-26

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Agency Information Collection Activities: Submission for OMB Review; Comment Request AGENCY: National Archives and Records Administration (NARA). ACTION... concerning the following information collections: 1. Title: Statistical Research in Archival Records...

Policies and Procedures for Accessing Archived NASA Lunar Data via the Web

NASA Technical Reports Server (NTRS)

James, Nathan L.; Williams, David R.

2011-01-01

The National Space Science Data Center (NSSDC) was established by NASA to provide for the preservation and dissemination of scientific data from NASA missions. This paper describes the policies specifically related to lunar science data. NSSDC presently archives 660 lunar data collections. Most of these data (423 units) are stored offline in analog format. The remainder of this collection consists of magnetic tapes and discs containing approximately 1.7 TB of digital lunar data. The active archive for NASA lunar data is the Planetary Data System (PDS). NSSDC has an agreement with the PDS Lunar Data Node to assist in the restoration and preparation of NSSDC-resident lunar data upon request for access and distribution via the PDS archival system. Though much of NSSDC's digital store also resides in PDS, NSSDC has many analog data collections and some digital lunar data sets that are not in PDS. NSSDC stands ready to make these archived lunar data accessible to both the research community and the general public upon request as resources allow. Newly requested offline lunar data are digitized and moved to near-line storage devices called digital linear tape jukeboxes. The data are then packaged and made network-accessible via FTP for the convenience of a growing segment of the user community. This publication will 1) discuss the NSSDC processes and policies that govern how NASA lunar data is preserved, restored, and made accessible via the web and 2) highlight examples of special lunar data requests.

Adaptability in the Development of Data Archiving Services at Johns Hopkins University

NASA Astrophysics Data System (ADS)

Petters, J.; DiLauro, T.; Fearon, D.; Pralle, B.

2015-12-01

Johns Hopkins University (JHU) Data Management Services provides archiving services for institutional researchers through the JHU Data Archive, thereby increasing the access to and use of their research data. From its inception our unit's archiving service has evolved considerably. While some of these changes have been internally driven so that our unit can archive quality data collections more efficiently, we have also developed archiving policies and procedures on the fly in response to researcher needs. Providing our archiving services for JHU research groups from a variety of research disciplines have surfaced different sets of expectations and needs. We have used each interaction to help us refine our services and quickly satisfy the researchers we serve (following the first agile principle). Here we discuss the development of our newest archiving service model, its implementation over the past several months, and the processes by which we have continued to refine and improve our archiving services since its implementation. Through this discussion we will illustrate the benefits of planning, structure and flexibility in development of archiving services that maximize the potential value of research data. We will describe interactions with research groups, including those from environmental engineering and international health, and how we were able to rapidly modify and develop our archiving services to meet their needs (e.g. in an 'agile' way). For example, our interactions with both of these research groups led first to discussion in regular standing meetings and eventually development of new archiving policies and procedures. These policies and procedures centered on limiting access to archived research data while associated manuscripts progress through peer-review and publication.

The SpaceInn SISMA archive

NASA Astrophysics Data System (ADS)

Rainer, Monica; Poretti, Ennio; Mistò, Angelo; Rosa Panzera, Maria

2017-10-01

The Spectroscopic Indicators in a SeisMic Archive (SISMA) has been built in the framework of the FP7 SpaceInn project to contain the 7013 HARPS spectra observed during the CoRoT asteroseismic groundbased program, along with their variability and asteroseismic indicators. The spectra pertain to 261 stars spread around the whole Herztsprung-Russell diagram: 72 of them were CoRoT targets while the others were observed in order to better characterize their variability classes. The Legacy Data lightcurves of the CoRoT targets are also stored in the archive.

Managing Data and Facilitating Science: A spectrum of activities in the Centre for Environmental Data Archival. (Invited)

NASA Astrophysics Data System (ADS)

Lawrence, B.; Bennett, V.; Callaghan, S.; Juckes, M. N.; Pepler, S.

2013-12-01

The UK Centre for Environmental Data Archival (CEDA) hosts a number of formal data centres, including the British Atmospheric Data Centre (BADC), and is a partner in a range of national and international data federations, including the InfraStructure for the European Network for Earth system Simulation, the Earth System Grid Federation, and the distributed IPCC Data Distribution Centres. The mission of CEDA is to formally curate data from, and facilitate the doing of, environmental science. The twin aims are symbiotic: data curation helps facilitate science, and facilitating science helps with data curation. Here we cover how CEDA delivers this strategy by established internal processes supplemented by short-term projects, supported by staff with a range of roles. We show how CEDA adds value to data in the curated archive, and how it supports science, and show examples of the aforementioned symbiosis. We begin by discussing curation: CEDA has the formal responsibility for curating the data products of atmospheric science and earth observation research funded by the UK Natural Environment Research Council (NERC). However, curation is not just about the provider community, the consumer communities matter too, and the consumers of these data cross the boundaries of science, including engineers, medics, as well as the gamut of the environmental sciences. There is a small, and growing cohort of non-science users. For both producers and consumers of data, information about data is crucial, and a range of CEDA staff have long worked on tools and techniques for creating, managing, and delivering metadata (as well as data). CEDA "science support" staff work with scientists to help them prepare and document data for curation. As one of a spectrum of activities, CEDA has worked on data Publication as a method of both adding value to some data, and rewarding the effort put into the production of quality datasets. As such, we see this activity as both a curation and a

Interrogating trees as archives of sulphur deposition

NASA Astrophysics Data System (ADS)

Wynn, P. M.; Loader, N. J.; Fairchild, I. J.

2012-04-01

A principal driver of climatic variability over the past 1,000 years and essential forcing mechanism for climate, are the changes in atmospheric composition resulting from sulphur aerosols. Natural and anthropogenic aerosols released into the atmosphere disrupt the radiative balance through backscattering and absorption of incoming solar radiation and increase cloud albedo by acting as condensation nuclei. Understanding the impact of sulphur emissions upon climate beyond the last few hundred years however is not straightforward and natural archives of environmental information must be explored. Tree-rings represent one such archive as they are widely distributed and preserve environmental information within a precisely dateable, annually resolved timescale. Until recently the sulphur contained within tree-rings has largely remained beyond the reach of environmental scientists and climate modelers owing to difficulties associated with the extraction of a robust signal and uncertainties regarding post-depositional mobility. Our recent work using synchrotron radiation has established that the majority of non-labile sulphur in two conifer species is preserved within the cellular structure of the woody tissue after uptake and demonstrates an increasing trend in sulphur concentration during the 20th century and during known volcanic events. Due to the clear isotopic distinction between marine (+21), geological (+10 to +30), atmospheric pollution (-3 to +9 ) and volcanic sources of sulphur (0 to +5), isotopic ratios provide a diagnostic tool with which changes in the source of atmospheric sulphur can be detected in a more reliable fashion than concentration alone. Sulphur isotopes should thereby provide a fingerprint of short lived events including volcanic activity when extracted at high resolution and in conjunction with high resolution S concentrations defining the event. Here we present methodologies associated with extracting the sulphur isotopic signal from tree

The archiving and dissemination of biological structure data.

PubMed

Berman, Helen M; Burley, Stephen K; Kleywegt, Gerard J; Markley, John L; Nakamura, Haruki; Velankar, Sameer

2016-10-01

The global Protein Data Bank (PDB) was the first open-access digital archive in biology. The history and evolution of the PDB are described, together with the ways in which molecular structural biology data and information are collected, curated, validated, archived, and disseminated by the members of the Worldwide Protein Data Bank organization (wwPDB; http://wwpdb.org). Particular emphasis is placed on the role of community in establishing the standards and policies by which the PDB archive is managed day-to-day. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

76 FR 29012 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-19

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Agency Information Collection Activities: Submission for OMB Review; Comment Request AGENCY: National Archives and Records Administration (NARA). ACTION... Personnel Records Center (NPRC) of the National Archives and Records Administration (NARA) administers...

78 FR 50451 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-19

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION [NARA-2013-041] Agency Information Collection Activities: Submission for OMB Review; Comment Request AGENCY: National Archives and Records Administration... following information collection: Title: National Archives and Records Administration Training and Event...

From Archive to Awards Ceremony: An Approach for Engaging Students in Historical Research

ERIC Educational Resources Information Center

Erekson, Keith A.

2011-01-01

Recent literature on history teaching has emphasized "doing history"--whether as "active learning", cognitive science, or with simple photocopies of primary sources. This article extends the discussion of a "signature pedagogy" of history to include all aspects of the work of historians, from archival research through…

CAA Annual Report Fiscal Year 1998.

DTIC Science & Technology

1998-12-01

Studies , 3-1 Quick Reaction Analyses & Projects 3-1 4 TECHNOLOGY RESEARCH AND ANALYSIS SUPPORT 4-1 Technology Research 4-1 Methodology Research 4-2...Publications, Graphics, and Reproduction 5-2 6 ANALYTICAL EFFORTS COMPLETED BETWEEN FY90 AND FY98 6-1 Appendix A Annual Study , Work Evaluation...future. Chapter 2 highlights major studies and analysis activities which occurred in FY 98. Chapter 3 is the total package of analytical summaries

76 FR 52991 - Renewal of Advisory Committee on Electronic Records Archives

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-24

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Renewal of Advisory Committee on Electronic Records... Records Administration's (NARA) Advisory Committee on Electronic Records Archives. In accordance with... Committee on Electronic Records Archives in NARA's ceiling of discretionary advisory committees. FOR FURTHER...

Long-term archiving and data access: modelling and standardization

NASA Technical Reports Server (NTRS)

Hoc, Claude; Levoir, Thierry; Nonon-Latapie, Michel

1996-01-01

This paper reports on the multiple difficulties inherent in the long-term archiving of digital data, and in particular on the different possible causes of definitive data loss. It defines the basic principles which must be respected when creating long-term archives. Such principles concern both the archival systems and the data. The archival systems should have two primary qualities: independence of architecture with respect to technological evolution, and generic-ness, i.e., the capability of ensuring identical service for heterogeneous data. These characteristics are implicit in the Reference Model for Archival Services, currently being designed within an ISO-CCSDS framework. A system prototype has been developed at the French Space Agency (CNES) in conformance with these principles, and its main characteristics will be discussed in this paper. Moreover, the data archived should be capable of abstract representation regardless of the technology used, and should, to the extent that it is possible, be organized, structured and described with the help of existing standards. The immediate advantage of standardization is illustrated by several concrete examples. Both the positive facets and the limitations of this approach are analyzed. The advantages of developing an object-oriented data model within this contxt are then examined.

Archive Inventory Management System (AIMS) — A Fast, Metrics Gathering Framework for Validating and Gaining Insight from Large File-Based Data Archives

NASA Astrophysics Data System (ADS)

Verma, R. V.

2018-04-01

The Archive Inventory Management System (AIMS) is a software package for understanding the distribution, characteristics, integrity, and nuances of files and directories in large file-based data archives on a continuous basis.

News from the ESO Science Archive Facility

NASA Astrophysics Data System (ADS)

Dobrzycki, A.; Arnaboldi, M.; Bierwirth, T.; Boelter, M.; Da Rocha, C.; Delmotte, N.; Forchì, V.; Fourniol, N.; klein Gebbinck, M.; Lange, U.; Mascetti, L.; Micol, A.; Moins, C.; Munte, C.; Pluciennik, C.; Retzlaff, J.; Romaniello, M.; Rosse, N.; Sequeiros, I. V.; Vuong, M.-H.; Zampieri, S.

2015-09-01

ESO Science Archive Facility (SAF) - one of the world's biggest astronomical archives - combines two roles: operational (ingest, tallying, safekeeping and distribution to observers of raw data taken with ESO telescopes and processed data generated both internally and externally) and scientific (publication and delivery of all flavours of data to external users). This paper presents the “State of the SAF.” SAF, as a living entity, is constantly implementing new services and upgrading the existing ones. We present recent and future developments related to the Archive's Request Handler and metadata handling as well as performance and usage statistics and trends. We also discuss the current and future datasets on offer at SAF.

Operating a petabyte class archive at ESO

NASA Astrophysics Data System (ADS)

Suchar, Dieter; Lockhart, John S.; Burrows, Andrew

2008-07-01

The challenges of setting up and operating a Petabyte Class Archive will be described in terms of computer systems within a complex Data Centre environment. The computer systems, including the ESO Primary and Secondary Archive and the associated computational environments such as relational databases will be explained. This encompasses the entire system project cycle, including the technical specifications, procurement process, equipment installation and all further operational phases. The ESO Data Centre construction and the complexity of managing the environment will be presented. Many factors had to be considered during the construction phase, such as power consumption, targeted cooling and the accumulated load on the building structure to enable the smooth running of a Petabyte class Archive.

Remediation of the protein data bank archive

PubMed Central

Henrick, Kim; Feng, Zukang; Bluhm, Wolfgang F.; Dimitropoulos, Dimitris; Doreleijers, Jurgen F.; Dutta, Shuchismita; Flippen-Anderson, Judith L.; Ionides, John; Kamada, Chisa; Krissinel, Eugene; Lawson, Catherine L.; Markley, John L.; Nakamura, Haruki; Newman, Richard; Shimizu, Yukiko; Swaminathan, Jawahar; Velankar, Sameer; Ory, Jeramia; Ulrich, Eldon L.; Vranken, Wim; Westbrook, John; Yamashita, Reiko; Yang, Huanwang; Young, Jasmine; Yousufuddin, Muhammed; Berman, Helen M.

2008-01-01

The Worldwide Protein Data Bank (wwPDB; wwpdb.org) is the international collaboration that manages the deposition, processing and distribution of the PDB archive. The online PDB archive at ftp://ftp.wwpdb.org is the repository for the coordinates and related information for more than 47 000 structures, including proteins, nucleic acids and large macromolecular complexes that have been determined using X-ray crystallography, NMR and electron microscopy techniques. The members of the wwPDB–RCSB PDB (USA), MSD-EBI (Europe), PDBj (Japan) and BMRB (USA)–have remediated this archive to address inconsistencies that have been introduced over the years. The scope and methods used in this project are presented. PMID:18073189

36 CFR § 1253.2 - National Archives at College Park.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true National Archives at College Park. § 1253.2 Section § 1253.2 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS... Park, MD 20740-6001. Hours for the Research Center are posted at http://www.archives.gov. The phone...

Metadata and Buckets in the Smart Object, Dumb Archive (SODA) Model

NASA Technical Reports Server (NTRS)

Nelson, Michael L.; Maly, Kurt; Croom, Delwin R., Jr.; Robbins, Steven W.

2004-01-01

We present the Smart Object, Dumb Archive (SODA) model for digital libraries (DLs), and discuss the role of metadata in SODA. The premise of the SODA model is to "push down" many of the functionalities generally associated with archives into the data objects themselves. Thus the data objects become "smarter", and the archives "dumber". In the SODA model, archives become primarily set managers, and the objects themselves negotiate and handle presentation, enforce terms and conditions, and perform data content management. Buckets are our implementation of smart objects, and da is our reference implementation for dumb archives. We also present our approach to metadata translation for buckets.

Phytochemical profiles and antioxidant activities of Chinese dark teas obtained by different processing technologies.

PubMed

Lv, Hai-Peng; Zhang, Yue; Shi, Jiang; Lin, Zhi

2017-10-01

Dark teas are rich in secondary metabolites, such as phenolics and flavonoids, which have been suggested to be associated with their health benefits. In this study, the concentrations of tea polyphenols, tea pigments, catechins, flavonoids, alkaloid, and volatile components in 44 dark tea samples, including Pu-erh, Fuzhuan and Liubao teas, were systematically examined. Among the samples tested, Pu-erh tea contained the highest total flavonoid content (5.24±0.05%), followed by Liubao (4.45±0.61%) and Fuzhuan teas (3.33±0.23%). The tea polyphenols levels in the dark teas were approximately 10%, and no statistically significant differences (p>0.05) were found among the different types. Hexadecanoic acid was the most abundant aroma component in the dark teas, accounting for 15-20% of the total volatile oils. Moreover, the antioxidant activities of these dark teas were analyzed using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt (ABTS) assay, ferric reducing antioxidant power (FRAP) assay, and cellular antioxidant activity (CAA) assay (HepG2 cells). The fat metabolism modulation activities (FMMA) of the dark teas were tested using a high-throughput screening method (SMMC-7221 cells). The results indicated that the different dark teas had diverse antioxidant activities, and the variation in the activities was significant. Correlation analysis showed that there was a significant positive correlation between the levels of EGCG and antioxidant activities measured using the ABTS (r=0.916) and FRAP (r=0.853) assays, and the levels of total flavonoids and theabrownins correlated well with the values determined using the CAA (r=0.845 and 0.865, respectively) assay. Copyright © 2016 Elsevier Ltd. All rights reserved.

75 FR 63208 - Advisory Committee on the Electronic Records Archives (ACERA)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-14

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on the Electronic Records Archives (ACERA) AGENCY: National Archives and Records Administration. ACTION: Notice of meeting. SUMMARY: In... and Records Administration (NARA) announces a meeting of the Advisory Committee on the Electronic...

76 FR 65218 - Advisory Committee on the Electronic Records Archives (ACERA)

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-20

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on the Electronic Records Archives (ACERA) AGENCY: National Archives and Records Administration. ACTION: Notice of meeting. SUMMARY: In... and Records Administration (NARA) announces a meeting of the Advisory Committee on the Electronic...

St. Petersburg Coastal and Marine Science Center's Core Archive Portal

USGS Publications Warehouse

Reich, Chris; Streubert, Matt; Dwyer, Brendan; Godbout, Meg; Muslic, Adis; Umberger, Dan

2012-01-01

This Web site contains information on rock cores archived at the U.S. Geological Survey (USGS) St. Petersburg Coastal and Marine Science Center (SPCMSC). Archived cores consist of 3- to 4-inch-diameter coral cores, 1- to 2-inch-diameter rock cores, and a few unlabeled loose coral and rock samples. This document - and specifically the archive Web site portal - is intended to be a 'living' document that will be updated continually as additional cores are collected and archived. This document may also contain future references and links to a catalog of sediment cores. Sediment cores will include vibracores, pushcores, and other loose sediment samples collected for research purposes. This document will: (1) serve as a database for locating core material currently archived at the USGS SPCMSC facility; (2) provide a protocol for entry of new core material into the archive system; and, (3) set the procedures necessary for checking out core material for scientific purposes. Core material may be loaned to other governmental agencies, academia, or non-governmental organizations at the discretion of the USGS SPCMSC curator.

78 FR 22345 - Advisory Committee on the Electronic Records Archives (ACERA)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-15

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on the Electronic Records Archives... and Records Administration (NARA) announces a meeting of the Advisory Committee on the Electronic... United States, on technical, mission, and service issues related to the Electronic Records Archives (ERA...

77 FR 21812 - Advisory Committee on the Electronic Records Archives (ACERA).

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-11

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on the Electronic Records Archives... and Records Administration (NARA) announces a meeting of the Advisory Committee on the Electronic... United States, on technical, mission, and service issues related to the Electronic Records Archives (ERA...

77 FR 56234 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-12

... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Agency Information Collection Activities: Submission for OMB Review; Comment Request AGENCY: National Archives and Records Administration (NARA). ACTION... not be viewed or advertised as an endorsement by the National Archives and Records Administration...

Commercial imagery archive product development

NASA Astrophysics Data System (ADS)

Sakkas, Alysa

1999-12-01

The Lockheed Martin (LM) team had garnered over a decade of operational experience in digital imagery management and analysis for the US Government at numerous worldwide sites. Recently, it set out to create a new commercial product to serve the needs of large-scale imagery archiving and analysis markets worldwide. LM decided to provide a turnkey commercial solution to receive, store, retrieve, process, analyze and disseminate in 'push' or 'pull' modes components and adapted and developed its own algorithms to provide added functionality not commercially available elsewhere. The resultant product, Intelligent Library System, satisfies requirements for (a) a potentially unbounded, data archive automated workflow management for increased user productivity; (c) automatic tracking and management of files stored on shelves; (d) ability to ingest, process and disseminate data involves with bandwidths ranging up to multi-gigabit per second; (e) access through a thin client- to-server network environment; (f) multiple interactive users needing retrieval of filters in seconds from both archived images or in real time, and (g) scalability that maintains information throughput performance as the size of the digital library grows.

Capillary cerebral amyloid angiopathy in Alzheimer's disease: association with allocortical/hippocampal microinfarcts and cognitive decline.

PubMed

Hecht, Moritz; Krämer, Lara Maria; von Arnim, Christine A F; Otto, Markus; Thal, Dietmar Rudolf

2018-05-01

Cerebral amyloid angiopathy (CAA) is caused by the deposition of the amyloid β-protein (Aβ) in the wall of cerebral and leptomeningeal blood vessels and is related to Alzheimer's disease (AD). Capillary Aβ deposition is observed in a subset of CAA cases and represents a distinct type of CAA named capillary CAA or CAA type 1. This type of CAA is strongly associated with the presence of the apolipoprotein E ε4 allele. CAA type 1-associated AD cases often exhibit a more severe Aβ plaque pathology but less widespread neurofibrillary tangle (NFT) pathology. The objective of this study was to analyze whether capillary CAA and its effects on cerebral blood flow have an impact on dementia. To address this objective, we performed neuropathological evaluation of 284 autopsy cases of demented and non-demented individuals. We assessed the presence of CAA and its subtypes as well as for that of hemorrhages and infarcts. Capillary CAA and CAA severity were associated with allocortical microinfarcts, comprising the CA1 region of the hippocampus. Allocortical microinfarcts, capillary CAA and CAA severity were, thereby, associated with cognitive decline. In conclusion, allocortical microinfarcts, CAA severity, and the capillary type of CAA were associated with one another and with the development of cognitive decline. Thus, AD cases with CAA type 1 (capillary CAA) appear to develop dementia symptoms not only due to AD-related Aβ plaque and NFT pathology but also due to hippocampal microinfarcts that are associated with CAA type 1 and CAA severity, and that damage a brain region important for memory function.

NVST Data Archiving System Based On FastBit NoSQL Database

NASA Astrophysics Data System (ADS)

Liu, Ying-bo; Wang, Feng; Ji, Kai-fan; Deng, Hui; Dai, Wei; Liang, Bo

2014-06-01

The New Vacuum Solar Telescope (NVST) is a 1-meter vacuum solar telescope that aims to observe the fine structures of active regions on the Sun. The main tasks of the NVST are high resolution imaging and spectral observations, including the measurements of the solar magnetic field. The NVST has been collecting more than 20 million FITS files since it began routine observations in 2012 and produces a maximum observational records of 120 thousand files in a day. Given the large amount of files, the effective archiving and retrieval of files becomes a critical and urgent problem. In this study, we implement a new data archiving system for the NVST based on the Fastbit Not Only Structured Query Language (NoSQL) database. Comparing to the relational database (i.e., MySQL; My Structured Query Language), the Fastbit database manifests distinctive advantages on indexing and querying performance. In a large scale database of 40 million records, the multi-field combined query response time of Fastbit database is about 15 times faster and fully meets the requirements of the NVST. Our study brings a new idea for massive astronomical data archiving and would contribute to the design of data management systems for other astronomical telescopes.

[Management and development of the dangerous preparation archive].

PubMed

Binetti, Roberto; Longo, Marcello; Scimonelli, Luigia; Costamagna, Francesca

2006-01-01

In the year 2000 an archive of dangerous preparations was created at the National Health Institute (Istituto Superiore di Sanità), following a principle included in the Directive 88/379/EEC on dangerous preparations, subsequently modified by the Directive 1999/45/EC, concerning the creation of a data bank on dangerous preparations in each European country. The information stored in the archive is useful for purposes of health consumer's and workers protection and prevention, and particularly in case of acute poisonings. The archive is fully informatised, therefore the companies can send the information using the web and the authorized Poison Centres can find the information on the archive using the web. In each Member State different procedures are in place to comply with the 1999/45/EC Directive; therefore an international coordination could be useful in order to create an European network of national data-banks on dangerous preparations.

The digital archive of the International Halley Watch

NASA Technical Reports Server (NTRS)

Klinglesmith, D. A., III; Niedner, M. B.; Grayzeck, E.; Aronsson, M.; Newburn, R. L.; Warnock, A., III

1992-01-01

The International Halley Watch was established to coordinate, collect, archive, and distribute the scientific data from Comet P/Halley that would be obtained from both the ground and space. This paper describes one of the end products of that effort, namely the IHW Digital Archive. The IHW Digital Archive consists of 26 CD-ROM's containing over 32 gigabytes of data from the 9 IHW disciplines as well as data from the 5 spacecraft missions flown to comet P/Haley and P/Giacobini-Zinner. The total archive contains over 50,000 observations by 1,500 observers from at least 40 countries. The first 24 CD's, which are currently available, contain data from the 9 IHW disciplines. The two remaining CD's will have the spacecraft data and should be available within the next year. A test CD-ROM of these data has been created and is currently under review.

The ESA Gaia Archive: Data Release 1

NASA Astrophysics Data System (ADS)

Salgado, J.; González-Núñez, J.; Gutiérrez-Sánchez, R.; Segovia, J. C.; Durán, J.; Hernández, J. L.; Arviset, C.

2017-10-01

The ESA Gaia mission is producing the most accurate source catalogue in astronomy to date. This represents a challenge in archiving to make the information and data accessible to astronomers in an efficient way, due to the size and complexity of the data. Also, new astronomical missions, taking larger and larger volumes of data, are reinforcing this change in the development of archives. Archives, as simple applications to access data, are evolving into complex data centre structures where computing power services are available for users and data mining tools are integrated into the server side. In the case of astronomy missions that involve the use of large catalogues, such as Gaia (or Euclid to come), the common ways to work on the data need to be changed to the following paradigm: "move the code close to the data". This implies that data mining functionalities are becoming a must to allow for the maximum scientific exploitation of the data. To enable these capabilities, a TAP+ interface, crossmatch capabilities, full catalogue histograms, serialisation of intermediate results in cloud resources, such as VOSpace etc., have been implemented for the Gaia Data Release 1 (DR1), to enable the exploitation of these science resources by the community without any bottlenecks in the connection bandwidth. We present the architecture, infrastructure and tools already available in the Gaia Archive DR1 (http://archives.esac.esa.int/gaia/) and we describe the capabilities and infrastructure.

Stewardship of very large digital data archives

NASA Technical Reports Server (NTRS)

Savage, Patric

1992-01-01

This paper addresses the problems foreseen by the author in stewarding the very large digital data archives that will accumulate during the mission of the Earth Orbiting Satellite (EOS). It focuses on the function of 'shepherding' archived digital data into an endless future. Stewardship entails a great deal more than storing and protecting the archive. It also includes all aspects of providing meaningful service to the community of users (scientists) who will want to access the data. The complete steward will be required to do the following: (1) provide against loss due to physical phenomena; (2) assure that data is not 'lost' due to storage technology obsolescence; (3) maintain data in a current formatting methodology with the additional requirement of being able to reconstitute the data to its original, as-received format; (4) secure against loss or pollution of data due to accidental, misguided, or willful software intrusion; (5) prevent unauthorized electronic access to the data, including unauthorized placement of data into the archive; (6) index the data in a metadatabase so that all anticipatable queries can be served without searching through the data itself; (7) provide responsive access to the metadatabase; (8) provide appropriately responsive access to the data; (9) incorporate additions and changes to the archive (and to the metadatabase) in a timely way; and (10) deliver only copies of data to clients - retain physical custody of the 'official' data. Items 1 through 4 are discussed in this paper.

Opportunistic Collaboration: Unlocking the Archives of the Birmingham Institute of Art and Design

ERIC Educational Resources Information Center

Everitt, Sian

2005-01-01

Purpose: To review a small specialist repository's strategic and opportunistic approach to utilising collaborative regional and national digital initiatives to increase access. The Birmingham Institute of Art and Design (BIAD) Archives activity is evaluated to determine whether a project-based approach recognises and meets the needs of historians,…

Data Information for Global Change Studies: NASA's Distributed Active Archive Centers and Cooperating Data Centers

NASA Technical Reports Server (NTRS)

2000-01-01

The Earth Observing System (EOS) is an integral part of the National Aeronautics and Space Administration's (NASA's) Earth Science Enterprise (ESE). ESE is a long-term global change research program designed to improve our understanding of the Earth's interrelated processes involving the atmosphere, oceans, land surfaces, and polar regions. Data from EOS instruments and other Earth science measurement systems are useful in understanding the causes and processes of global climate change and the consequences of human activities. The EOS Data and Information System (EOSDIS) provides a structure for data management and user services for products derived from EOS satellite instruments and other NASA Earth science data. Within the EOSDIS framework, the Distributed Active Archive Centers (DAACs) have been established to provide expertise in one or more Earth science disciplines. The DAACs and cooperating data centers provide data and information services to support the global change research community. Much of the development of the DAACs has been in anticipation of the enormous amount of data expected from EOS instruments to be launched within the next two decades. Terra, the EOS flagship launched in December 1999, is the first of a series of EOS satellites to carry several instruments with multispectral capabilities. Some data products from these instruments are now available from several of the DAACs. These and other data products can be ordered through the EOS Data Gateway (EDG) and DAAC-specific online ordering systems.

Integration experiences and performance studies of A COTS parallel archive systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Hsing-bung; Scott, Cody; Grider, Bary

2010-01-01

Current and future Archive Storage Systems have been asked to (a) scale to very high bandwidths, (b) scale in metadata performance, (c) support policy-based hierarchical storage management capability, (d) scale in supporting changing needs of very large data sets, (e) support standard interface, and (f) utilize commercial-off-the-shelf(COTS) hardware. Parallel file systems have been asked to do the same thing but at one or more orders of magnitude faster in performance. Archive systems continue to move closer to file systems in their design due to the need for speed and bandwidth, especially metadata searching speeds such as more caching and lessmore » robust semantics. Currently the number of extreme highly scalable parallel archive solutions is very small especially those that will move a single large striped parallel disk file onto many tapes in parallel. We believe that a hybrid storage approach of using COTS components and innovative software technology can bring new capabilities into a production environment for the HPC community much faster than the approach of creating and maintaining a complete end-to-end unique parallel archive software solution. In this paper, we relay our experience of integrating a global parallel file system and a standard backup/archive product with a very small amount of additional code to provide a scalable, parallel archive. Our solution has a high degree of overlap with current parallel archive products including (a) doing parallel movement to/from tape for a single large parallel file, (b) hierarchical storage management, (c) ILM features, (d) high volume (non-single parallel file) archives for backup/archive/content management, and (e) leveraging all free file movement tools in Linux such as copy, move, ls, tar, etc. We have successfully applied our working COTS Parallel Archive System to the current world's first petaflop/s computing system, LANL's Roadrunner, and demonstrated its capability to address requirements of future

Integration experiments and performance studies of a COTS parallel archive system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Hsing-bung; Scott, Cody; Grider, Gary

2010-06-16

Current and future Archive Storage Systems have been asked to (a) scale to very high bandwidths, (b) scale in metadata performance, (c) support policy-based hierarchical storage management capability, (d) scale in supporting changing needs of very large data sets, (e) support standard interface, and (f) utilize commercial-off-the-shelf (COTS) hardware. Parallel file systems have been asked to do the same thing but at one or more orders of magnitude faster in performance. Archive systems continue to move closer to file systems in their design due to the need for speed and bandwidth, especially metadata searching speeds such as more caching andmore » less robust semantics. Currently the number of extreme highly scalable parallel archive solutions is very small especially those that will move a single large striped parallel disk file onto many tapes in parallel. We believe that a hybrid storage approach of using COTS components and innovative software technology can bring new capabilities into a production environment for the HPC community much faster than the approach of creating and maintaining a complete end-to-end unique parallel archive software solution. In this paper, we relay our experience of integrating a global parallel file system and a standard backup/archive product with a very small amount of additional code to provide a scalable, parallel archive. Our solution has a high degree of overlap with current parallel archive products including (a) doing parallel movement to/from tape for a single large parallel file, (b) hierarchical storage management, (c) ILM features, (d) high volume (non-single parallel file) archives for backup/archive/content management, and (e) leveraging all free file movement tools in Linux such as copy, move, Is, tar, etc. We have successfully applied our working COTS Parallel Archive System to the current world's first petafiop/s computing system, LANL's Roadrunner machine, and demonstrated its capability to address requirements

Role and Justification of Web Archiving by National Libraries: A Questionnaire Survey

ERIC Educational Resources Information Center

Shiozaki, Ryo; Eisenschitz, Tamara

2009-01-01

This paper reports on a questionnaire survey of 16 national libraries designed to clarify how national libraries attempt to justify their web archiving activities. Results indicate they envisage that a) the benefits brought about by their initiatives are greater than the overall costs, b) the costs imposed on libraries are greater than the costs…

Archiving of Wideband Plasma Wave Data

NASA Technical Reports Server (NTRS)

Kurth, William S.

1997-01-01

Beginning with the third year of funding, we began a more ambitious archiving production effort, minimizing work on new software and concentrating on building representative archives of the missions mentioned above, recognizing that only a small percentage of the data from any one mission can be archived with reasonable effort. We concentrated on data from Dynamics Explorer and ISEE 1, archiving orbits or significant fractions of orbits which attempt to capture the essence of the mission and provide data which will hopefully be sufficient for ongoing and new research as well as to provide a reference to upcoming and current ISTP missions which will not fly in the same regions of space as the older missions and which will not have continuous wideband data. We archived approximately 181 Gigabytes of data, accounting for some 1582 hours of data. Included in these data are all of the AMPTE chemical releases, all of the Spacelab 2/PDP data obtained during the free-flight portion of its mission, as well as significant portions of the S3, DE-1, Imp-6, Hawkeye, Injun 5, and ISEE 1 and 2 data sets. Table 1 summarizes these data. All of the data archived are summarized in gif-formatted images of frequency-time spectrograms which are directly accessible via the internet. Each of the gif files are identified by year, day, and time as described in the Web page. This provides a user with a specific date/time in mind a way of determining very quickly if there is data for the interval in question and, by clicking on the file name, browsing the data. Alternately, a user can browse the data for interesting features and events simply by viewing each of the gif files. When a user finds data of interest, he/she can notify us by email of the time period involved. Based on the user's needs, we can provide data on a convenient medium or by ftp, or we can mount the appropriate data and provide access to our analysis tools via the network. We can even produce products such as plots or

SUBSTANCE ABUSE AND MENTAL HEALTH DATA ARCHIVE (SAMHDA)

EPA Science Inventory

The Substance Abuse and Mental Health Data Archive (SAMHDA) is an initiative of the Office of Applied Studies, Substance Abuse and Mental Health Services Administration (SAMHSA) of the United States Department of Health and Human Services. The goal of the archive is to provide re...

The Emirates Space Data Center, a PDS4-Compliant Data Archive

NASA Astrophysics Data System (ADS)

DeWolfe, A. W.; Al Hammadi, O.; Amiri, S.

2017-12-01

As part of the UAE's Emirates Mars Mission (EMM), we are constructing a data archive to preserve and distribute science data from this and future missions. The archive will be publicly accessible and will provide access to Level 2 and 3 science data products from EMM, as well as ancillary data such as SPICE kernels and mission event timelines. As a member of the International Planetary Data Alliance (IPDA), the UAE has committed to making its archive PDS4-compatible, and maintaining the archive beyond the end of the mission. EMM is scheduled to begin collecting science data in spring 2021, and the archive is expected to begin releasing data in September 2021.

The Gran Telescopio Canarias and Calar Alto Virtual Observatory Compliant Archives

NASA Astrophysics Data System (ADS)

Alacid, J. M.; Solano, E.; Jiménez-Esteban, F. M.; Velasco, A.

2014-05-01

The Gran Telescopio Canarias and Calar Alto archives are the result of the collaboration agreements between the Centro de Astrobiología and two entities: GRANTECAN S.A. and the Centro Astronómico Hispano Alemán (CAHA). The archives have been developed in the framework of the Spanish Virtual Observatory and are maintained by the Data Archive Unit at Centro de Astrobiología. The archives contain both raw and science ready data and have been designed in compliance with the standards defined by the International Virtual Observatory Alliance, which guarantees a high level of data accessibility and handling. In this paper we describe the main characteristics and functionalities of both archives.

The Gran Telescopio Canarias and Calar Alto Virtual Observatory compliant archives

NASA Astrophysics Data System (ADS)

Solano, Enrique; Gutiérrez, Raúl; Alacid, José Manuel; Jiménez-Esteban, Francisco; Velasco Trasmonte, Almudena

2012-09-01

The Gran Telescopio Canarias (GTC) and Calar Alto archives are the result of the collaboration agreements between the Centro de Astrobiología (CAB, INTA-CSIC)) and two entities: GRANTECAN S.A. and the Centro Astronómico Hispano Alemán (CAHA). The archives have been developed in the framework of the Spanish Virtual Observatory and are maintained by the Data Archive Unit at CAB. The archives contain both raw and science ready data and have been designed in compliance with the standards defined by the International Virtual Observatory Alliance (IVOA) which guarantees a high level of data accessibility and handling. In this paper we describe the main characteristics and functionalities of both archives.

Enhancement of real-time EPICS IOC PV management for the data archiving system

NASA Astrophysics Data System (ADS)

Kim, Jae-Ha

2015-10-01

The operation of a 100-MeV linear proton accelerator, the major driving values and experimental data need to be archived. According to the experimental conditions, different data are required. Functions that can add new data and delete data in real time need to be implemented. In an experimental physics and industrial control system (EPICS) input output controller (IOC), the value of process variables (PVs) are matched with the driving values and data. The PV values are archived in text file format by using the channel archiver. There is no need to create a database (DB) server, just a need for large hard disk. Through the web, the archived data can be loaded, and new PV values can be archived without stopping the archive engine. The details of the implementation of a data archiving system with channel archiver are presented, and some preliminary results are reported.

Expansion of the On-line Archive "Statistically Downscaled WCRP CMIP3 Climate Projections"

NASA Astrophysics Data System (ADS)

Brekke, L. D.; Pruitt, T.; Maurer, E. P.; Das, T.; Duffy, P.; White, K.

2009-12-01

Presentation highlights status and plans for a public-access archive of downscaled CMIP3 climate projections. Incorporating climate projection information into long-term evaluations of water and energy resources requires analysts to have access to projections at "basin-relevant" resolution. Such projections would ideally be bias-corrected to account for climate model tendencies to systematically simulate historical conditions different than observed. In 2007, the U.S. Bureau of Reclamation, Santa Clara University and Lawrence Livermore National Laboratory (LLNL) collaborated to develop an archive of 112 bias-corrected and spatially disaggregated (BCSD) CMIP3 temperature and precipitation projections. These projections were generated using 16 CMIP3 models to simulate three emissions pathways (A2, A1b, and B1) from one or more initializations (runs). Projections are specified on a monthly time step from 1950-2099 and at 0.125 degree spatial resolution within the North American Land Data Assimilation System domain (i.e. contiguous U.S., southern Canada and northern Mexico). Archive data are freely accessible at LLNL Green Data Oasis (url). Since being launched, the archive has served over 3500 data requests by nearly 500 users in support of a range of planning, research and educational activities. Archive developers continue to look for ways to improve the archive and respond to user needs. One request has been to serve the intermediate datasets generated during the BCSD procedure, helping users to interpret the relative influences of the bias-correction and spatial disaggregation on the transformed CMIP3 output. This request has been addressed with intermediate datasets now posted at the archive web-site. Another request relates closely to studying hydrologic and ecological impacts under climate change, where users are asking for projected diurnal temperature information (e.g., projected daily minimum and maximum temperature) and daily time step resolution. In

Archiving InSight Lander Science Data Using PDS4 Standards

NASA Astrophysics Data System (ADS)

Stein, T.; Guinness, E. A.; Slavney, S.

2017-12-01

The InSight Mars Lander is scheduled for launch in 2018, and science data from the mission will be archived in the NASA Planetary Data System (PDS) using the new PDS4 standards. InSight is a geophysical lander with a science payload that includes a seismometer, a probe to measure subsurface temperatures and heat flow, a suite of meteorology instruments, a magnetometer, an experiment using radio tracking, and a robotic arm that will provide soil physical property information based on interactions with the surface. InSight is not the first science mission to archive its data using PDS4. However, PDS4 archives do not currently contain examples of the kinds of data that several of the InSight instruments will produce. Whereas the existing common PDS4 standards were sufficient for most of archiving requirements of InSight, the data generated by a few instruments required development of several extensions to the PDS4 information model. For example, the seismometer will deliver a version of its data in SEED format, which is standard for the terrestrial seismology community. This format required the design of a new product type in the PDS4 information model. A local data dictionary has also been developed for InSight that contains attributes that are not part of the common PDS4 dictionary. The local dictionary provides metadata relevant to all InSight data sets, and attributes specific to several of the instruments. Additional classes and attributes were designed for the existing PDS4 geometry dictionary that will capture metadata for the lander position and orientation, along with camera models for stereo image processing. Much of the InSight archive planning and design work has been done by a Data Archiving Working Group (DAWG), which has members from the InSight project and the PDS. The group coordinates archive design, schedules and peer review of the archive documentation and test products. The InSight DAWG archiving effort for PDS is being led by the PDS Geosciences

Archiving Mars Mission Data Sets with the Planetary Data System

NASA Technical Reports Server (NTRS)

Guinness, Edward A.

2006-01-01

This viewgraph presentation reviews the use of the Planetary Data System (PDS) to archive the datasets that are received from the Mars Missions. It reviews the lessons learned in the actual archiving process, and presents an overview of the actual archiving process. It also reviews the lessons learned from the perspectives of the projects, the data producers and the data users.

Astro-H Data Analysis, Processing and Archive

NASA Technical Reports Server (NTRS)

Angelini, Lorella; Terada, Yukikatsu; Loewenstein, Michael; Miller, Eric D.; Yamaguchi, Hiroya; Yaqoob, Tahir; Krimm, Hans; Harrus, Ilana; Takahashi, Hiromitsu; Nobukawa, Masayoshi;

Strike Up the Score: Deriving Searchable and Playable Digital Formats from Sheet Music; Smart Objects and Open Archives; Building the Archives of the Future: Advanced in Preserving Electronic Records at the National Archives and Records Administration; From the Digitized to the Digital Library.

ERIC Educational Resources Information Center

Choudhury, G. Sayeed; DiLauro, Tim; Droettboom, Michael; Fujinaga, Ichiro; MacMillan, Karl; Nelson, Michael L.; Maly, Kurt; Thibodeau, Kenneth; Thaller, Manfred

2001-01-01

These articles describe the experiences of the Johns Hopkins University library in digitizing their collection of sheet music; motivation for buckets, Smart Object, Dumb Archive (SODA) and the Open Archives Initiative (OAI), and initial experiences using them in digital library (DL) testbeds; requirements for archival institutions, the National…

The COROT ground-based archive and access system

NASA Astrophysics Data System (ADS)

Solano, E.; González-Riestra, R.; Catala, C.; Baglin, A.

2002-01-01

A prototype of the COROT ground-based archive and access system is presented here. The system has been developed at LAEFF and it is based on the experience gained at Laboratorio de Astrofisica Espacial y Fisica Fundamental (LAEFF) with the INES (IUE Newly Extracted System) Archive.

Social Science Data Archives and Libraries: A View to the Future.

ERIC Educational Resources Information Center

Clark, Barton M.

1982-01-01

Discusses factors militating against integration of social science data archives and libraries in near future, noting usage of materials, access requisite skills of librarians, economic stability of archives, existing structures which manage social science data archives. Role of librarians, data access tools, and cataloging of machine-readable…

Simple, Script-Based Science Processing Archive

NASA Technical Reports Server (NTRS)

Lynnes, Christopher; Hegde, Mahabaleshwara; Barth, C. Wrandle

2007-01-01

The Simple, Scalable, Script-based Science Processing (S4P) Archive (S4PA) is a disk-based archival system for remote sensing data. It is based on the data-driven framework of S4P and is used for data transfer, data preprocessing, metadata generation, data archive, and data distribution. New data are automatically detected by the system. S4P provides services such as data access control, data subscription, metadata publication, data replication, and data recovery. It comprises scripts that control the data flow. The system detects the availability of data on an FTP (file transfer protocol) server, initiates data transfer, preprocesses data if necessary, and archives it on readily available disk drives with FTP and HTTP (Hypertext Transfer Protocol) access, allowing instantaneous data access. There are options for plug-ins for data preprocessing before storage. Publication of metadata to external applications such as the Earth Observing System Clearinghouse (ECHO) is also supported. S4PA includes a graphical user interface for monitoring the system operation and a tool for deploying the system. To ensure reliability, S4P continuously checks stored data for integrity, Further reliability is provided by tape backups of disks made once a disk partition is full and closed. The system is designed for low maintenance, requiring minimal operator oversight.

Science Archives in the 21st Century: A NASA LAMBDA Report

NASA Technical Reports Server (NTRS)

Butterworth, P.; Greason, M.

2007-01-01

Lambda is a thematic data center that focuses on serving the cosmic microwave background (CMB) research community. LAMBDA is an active archive for NASA's Cosmic Background Explorer (COBE) and Wilkinson Microwave Anisotropy Probe (WMAP) mission data sets. In addition, LAMBDA provides analysis software, on-line tools, relevant ancillary data and important web links. LAMBDA also tries to preserve the most important ground-based and suborbital CMB data sets. CMB data is unlike other astrophysical data, consisting of intrinsically diffuse surface brightness photometry with a signal contrast of the order 1 part in 100,000 relative to the uniform background. Because of the extremely faint signal levels, the signal-to-noise ratio is relatively low and detailed instrument-specific knowledge of the data is essential. While the number of data sets being produced is not especially large, those data sets are becoming large and complex. That tendency will increase when the many polarization experiments currently being deployed begin producing data. The LAMBDA experience supports many aspects of the NASA data archive model developed informally over the last ten years-that small focused data centers are often more effective than larger more ambitious collections, for example; that data centers are usually best run by active scientists; that it can be particularly advantageous if those scientists are leaders in the use of the archived data sets; etc. LAMBDA has done some things so well that they might provide lessons for other archives. A lot of effort has been devoted to developing a simple and consistent interface to data sets, for example; and serving all the documentation required via simple 'more' pages and longer explanatory supplements. Many of the problems faced by LAMBDA will also not surprise anyone trying to manage other space science data. These range from persuading mission scientists to provide their data as quickly as possible, to dealing with a high volume of

The ExoMars Rover Science Archive: Status and Plans

NASA Astrophysics Data System (ADS)

Heather, D.; Lim, T.; Metcalfe, L.

2017-09-01

The ExoMars program is a co-operation between ESA and Roscosmos comprising two missions: the first, launched on 14 March 2016, included the Trace Gas Orbiter and Schiaparelli lander; the second, due for launch in 2020, will be a Rover and Surface Platform (RSP). The ExoMars Rover and Surface Platform deliveries will be among the first data in the PSA to be formatted according to the new PDS4 Standards, and will be the first rover data to be hosted within the archive at all. The archiving and management of the science data to be returned from ExoMars will require a significant development effort for the new Planetary Science Archive (PSA). This presentation will outline the current plans for archiving of the ExoMars Rover and Surface Platform science data.

Seabird tissue archival and monitoring project: Protocol for collecting and banking seabird eggs

USGS Publications Warehouse

Weston-York, Geoff; Porter, Barbara J.; Pugh, Rebecca S.; Roseneau, David G.; Simac, Kristin S.; Becker, Paul R.; Thorsteinson, Lyman K.; Wise, Stephen A.

2001-01-01

Archiving biological and environmental samples for retrospective analysis is a major component of systematic environmental monitoring. The long-term storage of carefully selected, representative samples in an environmental specimen bank is an important complement to the real-time monitoring of the environment. These archived samples permit:The use of subsequently developed innovative analytical technology that was not available at the time the samples were archived, for clear state-of-art identification an~ quantification of analytes of interest,The identification and quantification of analytes that are of subsequent interest but that were not of interest at the time the samples were archived, andThe comparison of present and past analytical techniques and values, providing continued credibility of past analytical values, and allowing flexibility in environmental monitoring programs.Seabirds, including albatrosses, pelicans, cormorants, terns, kittiwakes, murres, guillemots, and puffins spend most of their lives at sea and have special adaptations for feeding in the marine environment, including the ability to excrete the excess salt obtained from ingesting seawater. Many species nest in dense groups (colonies) on steep, precipitous sea-cliffs and headlands.Seabirds are long-lived and slow to mature. They occupy high positions in the marine food web and are considered sensitive indicators for the marine environment (prey includes krill, small fish, and squid). Breeding success, timing of nesting, diets, and survival rates may provide early indications of changing environmental conditions (e.g., see Hatch et aI., 1993). Chemical analysis of seabird tissues, including egg contents, can be particularly useful in determining whether contaminants (and potential biological effects) associated with human industrial activities, such as offshore petroleum and mineral exploration and development, are accumulating in marine environments. The collection and archival of seabird

The European HST Science Data Archive. [and Data Management Facility (DMF)

NASA Technical Reports Server (NTRS)

Pasian, F.; Pirenne, B.; Albrecht, R.; Russo, G.

1993-01-01

The paper describes the European HST Science Data Archive. Particular attention is given to the flow from the HST spacecraft to the Science Data Archive at the Space Telescope European Coordinating Facility (ST-ECF); the archiving system at the ST-ECF, including the hardware and software system structure; the operations at the ST-ECF and differences with the Data Management Facility; and the current developments. A diagram of the logical structure and data flow of the system managing the European HST Science Data Archive is included.

BOOK REVIEW: Treasure-Hunting in Astronomical Plate Archives.

NASA Astrophysics Data System (ADS)

Kroll, Peter; La Dous, Constanze; Brauer, Hans-Juergen; Sterken, C.

This book consists of the proceedings of a conference on the exploration of the invaluable scientific treasure present in astronomical plate archives worldwide. The book incorporates fifty scientific papers covering almost 250 pages. There are several most useful papers, such as, for example, an introduction to the world's large plate archives that serves the purpose of a guide for the beginning user of plate archives. It includes a very useful list of twelve mayor archives with many details on their advantages (completeness, number of plates, classification system and homogeneity of time coverage) and their limitations (plate quality, access, electronic catalogues, photographic services, limiting magnitudes, search software and cost to the user). Other topics cover available contemporary digitization machines, the applications of commercial flatbed scanners, technical aspects of plate consulting, astrophysical applications and astrometric uses, data reduction, data archiving and retrieval, and strategies to find astrophysically useful information on plates. The astrophysical coverage is very broad: from solar-system bodies to variable stars, sky surveys and sky patrols covering the galactic and extragalactic domain and even gravitational lensing. The book concludes by an illuminating paper on ALADIN, the reference tool for identification of astronomical sources. This work can be considered as a kind of field guide, and is recommended reading for anyone who wishes to undertake small- or large-scale consulting of photographic plate material. A shortcoming of the proceedings is the fact that very few papers have abstracts. BOOK REVIEW: Treasure-Hunting in Astronomical Plate Archives. Proceedings of the international workshop held at Sonneberg Observatory, March 4-6, 1999. Peter Kroll, Constanze la Dous and Hans-Juergen Brauer (Eds.)

Kepler Archive Manual

NASA Technical Reports Server (NTRS)

Thompson, Susan E.; Fraquelli, Dorothy; Van Cleve, Jeffrey E.; Caldwell, Douglas A.

2016-01-01

A description of Kepler, its design, performance and operational constraints may be found in the Kepler Instrument Handbook (KIH, Van Cleve Caldwell 2016). A description of Kepler calibration and data processing is described in the Kepler Data Processing Handbook (KDPH, Jenkins et al. 2016; Fanelli et al. 2011). Science users should also consult the special ApJ Letters devoted to early Kepler results and mission design (April 2010, ApJL, Vol. 713 L79-L207). Additional technical details regarding the data processing and data qualities can be found in the Kepler Data Characteristics Handbook (KDCH, Christiansen et al. 2013) and the Data Release Notes (DRN). This archive manual specifically documents the file formats, as they exist for the last data release of Kepler, Data Release 25(KSCI-19065-002). The earlier versions of the archive manual and data release notes act as documentation for the earlier versions of the data files.

AstroCloud, a Cyber-Infrastructure for Astronomy Research: Data Archiving and Quality Control

NASA Astrophysics Data System (ADS)

He, B.; Cui, C.; Fan, D.; Li, C.; Xiao, J.; Yu, C.; Wang, C.; Cao, Z.; Chen, J.; Yi, W.; Li, S.; Mi, L.; Yang, S.

2015-09-01

AstroCloud is a cyber-Infrastructure for Astronomy Research initiated by Chinese Virtual Observatory (China-VO) under funding support from NDRC (National Development and Reform commission) and CAS (Chinese Academy of Sciences)1(Cui et al. 2014). To archive the astronomical data in China, we present the implementation of the astronomical data archiving system (ADAS). Data archiving and quality control are the infrastructure for the AstroCloud. Throughout the data of the entire life cycle, data archiving system standardized data, transferring data, logging observational data, archiving ambient data, And storing these data and metadata in database. Quality control covers the whole process and all aspects of data archiving.

PCB Analysis Plan for Tank Archive Samples

DOE Office of Scientific and Technical Information (OSTI.GOV)

NGUYEN, D.M.

2001-03-22

This analysis plan specifies laboratory analysis, quality assurance/quality control (QA/QC), and data reporting requirements for analyzing polychlorinated biphenyls (PCB) concentrations in archive samples. Tank waste archive samples that are planned for PCB analysis are identified in Nguyen 2001. The tanks and samples are summarized in Table 1-1. The analytical data will be used to establish a PCB baseline inventory in Hanford tanks.

The NASA Exoplanet Science Institute Archives: KOA and NStED

NASA Astrophysics Data System (ADS)

Berriman, G. B.; Ciardi, D.; Abajian, M.; Barlow, T.; Bryden, G.; von Braun, K.; Good, J.; Kane, S.; Kong, M.; Laity, A.; Lynn, M.; Elroy, D. M.; Plavchan, P.; Ramirez, S.; Schmitz, M.; Stauffer, J.; Wyatt, P.; Zhang, A.; Goodrich, R.; Mader, J.; Tran, H.; Tsubota, M.; Beekley, A.; Berukoff, S.; Chan, B.; Lau, C.; Regelson, M.; Saucedo, M.; Swain, M.

2010-12-01

The NASA Exoplanet Science Institute (NExScI) maintains a series of archival services in support of NASA’s planet finding and characterization goals. Two of the larger archival services at NExScI are the Keck Observatory Archive (KOA) and the NASA Star and Exoplanet Database (NStED). KOA, a collaboration between the W. M. Keck Observatory and NExScI, serves raw data from the High Resolution Echelle Spectrograph (HIRES) and extracted spectral browse products. As of June 2009, KOA hosts over 28 million files (4.7 TB) from over 2,000 nights. In Spring 2010, it will begin to serve data from the Near-Infrared Echelle Spectrograph (NIRSPEC). NStED is a general purpose archive with the aim of providing support for NASA’s planet finding and characterization goals, and stellar astrophysics. There are two principal components of NStED: a database of (currently) all known exoplanets, and images; and an archive dedicated to high precision photometric surveys for transiting exoplanets. NStED is the US portal to the CNES mission CoRoT, the first space mission dedicated to the discovery and characterization of exoplanets. These archives share a common software and hardware architecture with the NASA/IPAC Infrared Science Archive (IRSA). The software architecture consists of standalone utilities that perform generic query and retrieval functions. They are called through program interfaces and plugged together to form applications through a simple executive library.

Dusting the Archives of Childhood: Child Welfare Records as Historical Sources

ERIC Educational Resources Information Center

Vehkalahti, Kaisa

2016-01-01

Using administrative sources in the history of education and childhood involves a range of methodological and ethical considerations. This article discusses these problems, as well as the role of archives and archival policies in preserving history and shaping our understanding of past childhoods. Using Finnish child welfare archives from the…

Checklist of Standards Applicable to the Preservation of Archives and Manuscripts.

ERIC Educational Resources Information Center

Walch, Victoria Irons, Comp.

1990-01-01

Presents a checklist of more than 150 standards that have been identified by the Society of American Archivists (SAA) Task Force on Archival Standards as applicable to the preservation of archives and manuscripts. The organizations that developed the standards are described, and increased archival participation in the standards development process…

Increasing Access to Archival Records in Library Online Public Access Catalogs.

ERIC Educational Resources Information Center

Gilmore, Matthew B.

1988-01-01

Looks at the use of online public access catalogs, the utility of subject and call-number searching, and possible archival applications. The Wallace Archives at the Claremont Colleges is used as an example of the availability of bibliographic descriptions of multiformat archival materials through the library catalog. Sample records and searches…

The Council on Aviation Accreditation. Part 2; Contemporary Issues

NASA Technical Reports Server (NTRS)

Prather, C. Daniel

2007-01-01

The Council on Aviation Accreditation (CAA) was established in 1988 in response to the need for formal, specialized accreditation of aviation academic programs, as expressed by institutional members of the University Aviation Association (UAA). The first aviation programs were accredited by the CAA in 1992, and today, the CAA lists 60 accredited programs at 21 institutions nationwide. Although the number of accredited programs has steadily grown, there are currently only 20 percent of UAA member institutions with CAA accredited programs. In an effort to further understand this issue, a case study of the CAA was performed, which resulted in a two-part case study report. Part one addressed the historical foundation of the organization and the current environment in which the CAA functions. Part two focuses on the following questions: (a) what are some of the costs to a program seeking CAA accreditation (b) what are some fo the benefits of being CAA accredited; (c) why do programs seek CAA accreditation; (d) why do programs choose no to seek CAA accreditation; (e) what role is the CAA playing in the international aviation academic community; and (f) what are some possible strategies the CAA may adopt to enhance the benefits of CAA accreditation and increase the number of CAA accredited programs. This second part allows for a more thorough understanding of the contemporary issued faced by the organization, as well as alternative strategies for the CAA to consider in an effort to increase the number of CAA accredited programs and more fully fulfill the role of the CAA in the collegiate aviation community.

Teaching Electronic Records Management in the Archival Curriculum

ERIC Educational Resources Information Center

Zhang, Jane

2016-01-01

Electronic records management has been incorporated into the archival curriculum in North America since the 1990s. This study reported in this paper provides a systematic analysis of the content of electronic records management (ERM) courses currently taught in archival education programs. Through the analysis of course combinations and their…

The American Archival Profession and Information Technology Standards.

ERIC Educational Resources Information Center

Cox, Richard J.

1992-01-01

Discussion of the use of standards by archivists highlights the U.S. MARC AMC (Archives-Manuscript Control) format for reporting archival records and manuscripts; their interest in specific standards being developed for the OSI (Open Systems Interconnection) reference model; and the management of records in electronic formats. (16 references) (LAE)

Towards improving searches on the NASA's Distributed Active Archive Centers (DAACs)

NASA Astrophysics Data System (ADS)

McGibbney, L. J.; Whitehall, K. D.; Ramapriyan, H.; Khalsa, S. J. S.; Lynnes, C.; Armstrong, E. M.

2016-12-01

NASA supports numerous observing missions to study the Earth, its interactions, and understand its changes. These missions generate heterogeneous data from a variety of sources including satellites and airborne platforms. NASA's Earth Observing System Data and Information System (EOSDIS) is the capability in NASA's Earth Science Data Systems Program responsible for the end-to-end management of these science data. More specifically, the EOSDIS Distributed Active Archive Centers (DAACs) are the key entities that maintain, distribute these data and provide related data services for the mission data associated with a given property of the Earth System e.g. PO.DAAC for physical oceanographic data, NSIDC DAAC for snow and ice data. As the volume, variety and velocity of Earth science data grow, users are focused on high veracity (i.e., data quality), and as their needs become more diverse, they find it more difficult to readily find the data that best suits their purposes. For instance, simple keyword searches on most DAAC holdings return many datasets of potential interest but which are unranked either based on the content of the query or the historical data usage. The Earth Science Data System Working Group (ESDSWG) on Search Relevance WG started in May 2015 to address these concerns. The mandates of the WG are: to characterize the term "search relevance" as it relates to EOSDIS; to assess the current implementations towards search relevance; and to determine how practices and standards in industry and other domains can be applied to DAACs - in a federated-sense - in order to effectively serve the Earth Science data consumers. This poster will present the WG's insights into user profiles and behaviors accessing the DAACs, identify the core areas essential to improve search relevance across the DAACs (individually and collectively), and highlight ongoing efforts within NASA and similar organizations towards search relevance.

Viking Seismometer PDS Archive Dataset

NASA Astrophysics Data System (ADS)

Lorenz, R. D.

2016-12-01

The Viking Lander 2 seismometer operated successfully for over 500 Sols on the Martian surface, recording at least one likely candidate Marsquake. The Viking mission, in an era when data handling hardware (both on board and on the ground) was limited in capability, predated modern planetary data archiving, and ad-hoc repositories of the data, and the very low-level record at NSSDC, were neither convenient to process nor well-known. In an effort supported by the NASA Mars Data Analysis Program, we have converted the bulk of the Viking dataset (namely the 49,000 and 270,000 records made in High- and Event- modes at 20 and 1 Hz respectively) into a simple ASCII table format. Additionally, since wind-generated lander motion is a major component of the signal, contemporaneous meteorological data are included in summary records to facilitate correlation. These datasets are being archived at the PDS Geosciences Node. In addition to brief instrument and dataset descriptions, the archive includes code snippets in the freely-available language 'R' to demonstrate plotting and analysis. Further, we present examples of lander-generated noise, associated with the sampler arm, instrument dumps and other mechanical operations.

Archiving Software Systems: Approaches to Preserve Computational Capabilities

NASA Astrophysics Data System (ADS)

King, T. A.

2014-12-01

A great deal of effort is made to preserve scientific data. Not only because data is knowledge, but it is often costly to acquire and is sometimes collected under unique circumstances. Another part of the science enterprise is the development of software to process and analyze the data. Developed software is also a large investment and worthy of preservation. However, the long term preservation of software presents some challenges. Software often requires a specific technology stack to operate. This can include software, operating systems and hardware dependencies. One past approach to preserve computational capabilities is to maintain ancient hardware long past its typical viability. On an archive horizon of 100 years, this is not feasible. Another approach to preserve computational capabilities is to archive source code. While this can preserve details of the implementation and algorithms, it may not be possible to reproduce the technology stack needed to compile and run the resulting applications. This future forward dilemma has a solution. Technology used to create clouds and process big data can also be used to archive and preserve computational capabilities. We explore how basic hardware, virtual machines, containers and appropriate metadata can be used to preserve computational capabilities and to archive functional software systems. In conjunction with data archives, this provides scientist with both the data and capability to reproduce the processing and analysis used to generate past scientific results.

Large Scale Data Mining to Improve Usability of Data: An Intelligent Archive Testbed

NASA Technical Reports Server (NTRS)

Ramapriyan, Hampapuram; Isaac, David; Yang, Wenli; Morse, Steve

2005-01-01

Research in certain scientific disciplines - including Earth science, particle physics, and astrophysics - continually faces the challenge that the volume of data needed to perform valid scientific research can at times overwhelm even a sizable research community. The desire to improve utilization of this data gave rise to the Intelligent Archives project, which seeks to make data archives active participants in a knowledge building system capable of discovering events or patterns that represent new information or knowledge. Data mining can automatically discover patterns and events, but it is generally viewed as unsuited for large-scale use in disciplines like Earth science that routinely involve very high data volumes. Dozens of research projects have shown promising uses of data mining in Earth science, but all of these are based on experiments with data subsets of a few gigabytes or less, rather than the terabytes or petabytes typically encountered in operational systems. To bridge this gap, the Intelligent Archives project is establishing a testbed with the goal of demonstrating the use of data mining techniques in an operationally-relevant environment. This paper discusses the goals of the testbed and the design choices surrounding critical issues that arose during testbed implementation.

The long hold: Storing data at the National Archives

NASA Technical Reports Server (NTRS)

Thibodeau, Kenneth

1992-01-01

The National Archives is, in many respects, in a unique position. For example, I find people from other organizations describing an archival medium as one which will last for three to five years. At the National Archives, we deal with the centuries, not years. From our perspective, there is no archival medium for data storage, and we do not expect there will ever be one. Predicting the long-term future of information technology beyond a mere five or ten years approaches the occult arts. But one prediction is probably safe. It is that the technology will continue to change, at least until analysts start talking about the post-information age. If we did have a medium which lasted a hundred years or longer, we probably would not have a device capable of reading it. The issue of obsolescence, as opposed to media stability, is more complex and more costly. It is especially complex at the National Archives because of two other aspects of our peculiar position. The first aspect is that we deal with incoherent data. The second is that we are charged with satisfying unknown and unknowable requirements. A brief overview of these aspects is presented.

An External Archive-Guided Multiobjective Particle Swarm Optimization Algorithm.

PubMed

Zhu, Qingling; Lin, Qiuzhen; Chen, Weineng; Wong, Ka-Chun; Coello Coello, Carlos A; Li, Jianqiang; Chen, Jianyong; Zhang, Jun

2017-09-01

The selection of swarm leaders (i.e., the personal best and global best), is important in the design of a multiobjective particle swarm optimization (MOPSO) algorithm. Such leaders are expected to effectively guide the swarm to approach the true Pareto optimal front. In this paper, we present a novel external archive-guided MOPSO algorithm (AgMOPSO), where the leaders for velocity update are all selected from the external archive. In our algorithm, multiobjective optimization problems (MOPs) are transformed into a set of subproblems using a decomposition approach, and then each particle is assigned accordingly to optimize each subproblem. A novel archive-guided velocity update method is designed to guide the swarm for exploration, and the external archive is also evolved using an immune-based evolutionary strategy. These proposed approaches speed up the convergence of AgMOPSO. The experimental results fully demonstrate the superiority of our proposed AgMOPSO in solving most of the test problems adopted, in terms of two commonly used performance measures. Moreover, the effectiveness of our proposed archive-guided velocity update method and immune-based evolutionary strategy is also experimentally validated on more than 30 test MOPs.

The global Landsat archive: Status, consolidation, and direction

USGS Publications Warehouse

Wulder, Michael A.; White, Joanne C.; Loveland, Thomas; Woodcock, Curtis; Belward, Alan; Cohen, Warren B.; Fosnight, Eugene A.; Shaw, Jerad; Masek, Jeffery G.; Roy, David P.

2016-01-01

New and previously unimaginable Landsat applications have been fostered by a policy change in 2008 that made analysis-ready Landsat data free and open access. Since 1972, Landsat has been collecting images of the Earth, with the early years of the program constrained by onboard satellite and ground systems, as well as limitations across the range of required computing, networking, and storage capabilities. Rather than robust on-satellite storage for transmission via high bandwidth downlink to a centralized storage and distribution facility as with Landsat-8, a network of receiving stations, one operated by the U.S. government, the other operated by a community of International Cooperators (ICs), were utilized. ICs paid a fee for the right to receive and distribute Landsat data and over time, more Landsat data was held outside the archive of the United State Geological Survey (USGS) than was held inside, much of it unique. Recognizing the critical value of these data, the USGS began a Landsat Global Archive Consolidation (LGAC) initiative in 2010 to bring these data into a single, universally accessible, centralized global archive, housed at the Earth Resources Observation and Science (EROS) Center in Sioux Falls, South Dakota. The primary LGAC goals are to inventory the data held by ICs, acquire the data, and ingest and apply standard ground station processing to generate an L1T analysis-ready product. As of January 1, 2015 there were 5,532,454 images in the USGS archive. LGAC has contributed approximately 3.2 million of those images, more than doubling the original USGS archive holdings. Moreover, an additional 2.3 million images have been identified to date through the LGAC initiative and are in the process of being added to the archive. The impact of LGAC is significant and, in terms of images in the collection, analogous to that of having had twoadditional Landsat-5 missions. As a result of LGAC, there are regions of the globe that now have markedly improved

The GIK-Archive of sediment core radiographs with documentation

NASA Astrophysics Data System (ADS)

Grobe, Hannes; Winn, Kyaw; Werner, Friedrich; Driemel, Amelie; Schumacher, Stefanie; Sieger, Rainer

2017-12-01

The GIK-Archive of radiographs is a collection of X-ray negative and photographic images of sediment cores based on exposures taken since the early 1960s. During four decades of marine geological work at the University of Kiel, Germany, several thousand hours of sampling, careful preparation and X-raying were spent on producing a unique archive of sediment radiographs from several parts of the World Ocean. The archive consists of more than 18 500 exposures on chemical film that were digitized, geo-referenced, supplemented with metadata and archived in the data library PANGAEA®. With this publication, the images have become available open-access for use by the scientific community at https://doi.org/10.1594/PANGAEA.854841.

Reiterating "Asylum Archive": Documenting Direct Provision in Ireland

ERIC Educational Resources Information Center

Nedeljkovic, Vukasin

2018-01-01

Originally a coping mechanism for an artist housed in a Direct Provision Centres while seeking asylum in Ireland, "Asylum Archive" has become much more than that. In 2018, it is now a collaborative archive, interactive and intermedial online document, and a scholarly research project. This iteration includes five new images of Railway…

Comparative studies on the interaction of caffeic acid, chlorogenic acid and ferulic acid with bovine serum albumin

NASA Astrophysics Data System (ADS)

Li, Shuang; Huang, Kelong; Zhong, Ming; Guo, Jun; Wang, Wei-zheng; Zhu, Ronghua

2010-10-01

The substitution of the hydrogen on aromatic and esterification of carboxyl group of the phenol compounds plays an important role in their bio-activities. In this paper, caffeic acid (CaA), chlorogenic acid (ChA) and ferulic acid (FA) were selected to investigate the binding to bovine serum albumin (BSA) using UV absorption spectroscopy, fluorescence spectroscopy and synchronous fluorescence spectroscopy. It was found that the methoxyl group substituting for the 3-hydroxyl group of CaA decreased the affinity for BSA and the esterification of carboxyl group of CaA with quinic acid increased the affinities. The affinities of ChA and FA with BSA were more sensitive to the temperature than that of CaA with BSA. Synchronous fluorescence spectroscopy and time-resolved fluorescence indicated that the Stern-Volmer plots largely deviated from linearity at high concentrations and were caused by complete quenching of the tyrosine fluorescence of BSA.

Digital information management: a progress report on the National Digital Mammography Archive

NASA Astrophysics Data System (ADS)

Beckerman, Barbara G.; Schnall, Mitchell D.

2002-05-01

Digital mammography creates very large images, which require new approaches to storage, retrieval, management, and security. The National Digital Mammography Archive (NDMA) project, funded by the National Library of Medicine (NLM), is developing a limited testbed that demonstrates the feasibility of a national breast imaging archive, with access to prior exams; patient information; computer aids for image processing, teaching, and testing tools; and security components to ensure confidentiality of patient information. There will be significant benefits to patients and clinicians in terms of accessible data with which to make a diagnosis and to researchers performing studies on breast cancer. Mammography was chosen for the project, because standards were already available for digital images, report formats, and structures. New standards have been created for communications protocols between devices, front- end portal and archive. NDMA is a distributed computing concept that provides for sharing and access across corporate entities. Privacy, auditing, and patient consent are all integrated into the system. Five sites, Universities of Pennsylvania, Chicago, North Carolina and Toronto, and BWXT Y12, are connected through high-speed networks to demonstrate functionality. We will review progress, including technical challenges, innovative research and development activities, standards and protocols being implemented, and potential benefits to healthcare systems.

Architecture Studio Archive: A Case Study in the Comprehensive Digital Capture and Repository of Student Design Work as an Aid to Teaching, Research, and Accreditation

ERIC Educational Resources Information Center

Anderson, Ross; Arndell, Michael; Christensen, Sten

2009-01-01

The "Architecture Studio Archive" pilot sought to form a comprehensive digital archive of the diverse student work conducted in the first year of the Bachelor of Design in Architecture Degree at the University of Sydney. The design studio is the primary vehicle for teaching architectural design. It is a locus for creative activity, with…

Anatomical measurement of the ossicles in patients with congenital aural atresia and stenosis.

PubMed

Li, Jieying; Chen, Keguang; Li, Chenlong; Yin, Dongming; Zhang, Tianyu; Dai, Peidong

2017-10-01

Our aims were to measure and compare anatomical parameters of the ossicles in normal, congenital aural stenosis (CAS), and congenital aural atresia (CAA) ears. This retrospective study was performed using three-dimensional reconstructed images derived from computed tomography scans of 20 normal subjects, 20 CAS patients, and 20 CAA patients. The lengths of the malleus handle and long process of the incus were greater in normal ears than in CAS and CAA ears (all P < 0.05). The angles of the incudostapedial joint and between the short and long processes of the incus were smaller in normal ears than in CAS and CAA ears (all P < 0.05). There were no significant differences in the positions of the malleus head and incudomalleolar joint, the size of the malleus head, the length of the short process of the incus, or the angle of the incudomalleolar joint (P > 0.05). Anatomical parameters of the lower part, but not of the upper part, of the ossicular chain in CAS and CAA ears differed from those in normal ears. Different branchial arch origins of the upper and lower parts of the ossicular chain may explain these findings. Dysplasia of the second arch, which develops into the lower part of the ossicular chain, may contribute to ossicular malformation in CAA and CAS. Accurate radiographic measurement of malformed ossicles may be useful for reconstructive surgery of CAA and CAS using the patient's native ossicular chain and for choosing an appropriate place for active middle ear implants. Copyright © 2017. Published by Elsevier B.V.

An Integrated Nonlinear Analysis library - (INA) for solar system plasma turbulence

NASA Astrophysics Data System (ADS)

Munteanu, Costel; Kovacs, Peter; Echim, Marius; Koppan, Andras

2014-05-01

We present an integrated software library dedicated to the analysis of time series recorded in space and adapted to investigate turbulence, intermittency and multifractals. The library is written in MATLAB and provides a graphical user interface (GUI) customized for the analysis of space physics data available online like: Coordinated Data Analysis Web (CDAWeb), Automated Multi Dataset Analysis system (AMDA), Planetary Science Archive (PSA), World Data Center Kyoto (WDC), Ulysses Final Archive (UFA) and Cluster Active Archive (CAA). Three main modules are already implemented in INA : the Power Spectral Density (PSD) Analysis, the Wavelet and Intemittency Analysis and the Probability Density Functions (PDF) analysis.The layered structure of the software allows the user to easily switch between different modules/methods while retaining the same time interval for the analysis. The wavelet analysis module includes algorithms to compute and analyse the PSD, the Scalogram, the Local Intermittency Measure (LIM) or the Flatness parameter. The PDF analysis module includes algorithms for computing the PDFs for a range of scales and parameters fully customizable by the user; it also computes the Flatness parameter and enables fast comparison with standard PDF profiles like, for instance, the Gaussian PDF. The library has been already tested on Cluster and Venus Express data and we will show relevant examples. Research supported by the European Community's Seventh Framework Programme (FP7/2007-2013) under grant agreement no 313038/STORM, and a grant of the Romanian Ministry of National Education, CNCS UEFISCDI, project number PN-II-ID PCE-2012-4-0418.

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