Sample records for actively conducting research

  1. Planning and Conducting Research Activities.

    ERIC Educational Resources Information Center

    Christiansen, Richard L.

    1983-01-01

    Some directions and influences on dental research activities in the near future are discussed. Current challenges include international competition, fellowships, and equipment. Potential research activity includes preventive medicine, epidemiology, chronic illness, the elderly, bioengineering, materials research, nutrition, soft tissue research,…

  2. 30 CFR 280.3 - What requirements must I follow when I conduct prospecting or research activities?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... research activities? You must conduct G&G prospecting activities or scientific research activities under... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What requirements must I follow when I conduct prospecting or research activities? 280.3 Section 280.3 Mineral Resources MINERALS MANAGEMENT SERVICE...

  3. 30 CFR 280.3 - What requirements must I follow when I conduct prospecting or research activities?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... when I conduct prospecting or research activities? You must conduct G&G prospecting activities or scientific research activities under this part according to: (a) The Act; (b) The regulations in this part... prospecting or research activities? 280.3 Section 280.3 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT...

  4. 34 CFR 350.22 - What activities must a Rehabilitation Research and Training Center conduct?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Training Center conduct? 350.22 Section 350.22 Education Regulations of the Offices of the Department of... DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM What Rehabilitation Research and Training Centers Does the Secretary Assist? § 350.22 What activities must a Rehabilitation Research and Training...

  5. Review of physical activity measurement using accelerometers in older adults: considerations for research design and conduct.

    PubMed

    Murphy, Susan L

    2009-02-01

    Accelerometers are being increasingly used in studies of physical activity (PA) among older adults, however the use of these monitors requires some specialized knowledge and up-to-date information on technological innovations. The purpose of this review article is to provide researchers with a guide to some commonly-used accelerometers in order to better design and conduct PA research with older adults. A literature search was conducted to obtain all available literature on commonly-used accelerometers in older adult samples with specific attention to articles discussing research design. The use of accelerometers in older adults requires a basic understanding of the type being used, rationale for their placement, and attention to calibration when needed. The updated technology in some monitors should make study conduct less difficult, however comparison studies of the newer versus the older generation models will be needed. Careful considerations for design and conduct of accelerometer research as outlined in this review should help to enhance the quality and comparability of future research studies.

  6. Lessons learned from conducting qualitative research in a hospital.

    PubMed

    Woith, Wendy Mann; Jenkins, Sheryl Henry; Astroth, Kim Schafer; Kennedy, Julie A

    2014-11-01

    To examine unexpected barriers to the conduct of hospital research during a study of nurses' activation of rapid response teams. We interviewed hospital nurses regarding their decisions to activate rapid response teams and encountered unexpected barriers to the conduct of this study in the hospital setting. Experience of conducting qualitative research with bedside nurses in a community hospital. Review of the reports of others who have conducted hospital research. Barriers related to administrative support, environmental distractors, constraints on nurses' time, apparent lack of investment in research by staff and a cumbersome recruitment process are identified. Recommendations on study site selection, timing of research, gaining access to nurses, scheduling and conducting interviews, and transcribing recorded data are made. As evidence is necessary to deliver safe, quality care, it is important that nurses understand and participate in research. This participation involves not only conducting research, but also serving as subjects. Given the importance of bedside nurses' willingness to engage in research, it is crucial to understand factors that impede or assist their participation. We offer several recommendations to nurses conducting research in hospitals, including: ■ Seek hospitals that are supportive of research, yet not over-invested in the process. ■ Build extra time into data collection schedules to maximize flexibility and accommodate work-place demands. ■ Emphasise the relevance and benefits of the research to nurses.

  7. Overcoming the challenges of conducting physical activity and built environment research in Latin America: IPEN Latin America

    PubMed Central

    Salvo, Deborah; Reis, Rodrigo S.; Sarmiento, Olga L.; Pratt, Michael

    2014-01-01

    Objective There is evidence linking the built environment (BE) with physical activity (PA), but few studies have been conducted in Latin America (LA). State-of-the-art methods and protocols have been designed in and applied in high-income countries (HIC). In this paper we identify key challenges and potential solutions to conducting high quality PA and BE research in LA. Methods The experience of implementing the IPEN data collection protocol (IPEN: International Physical Activity Environment Network) in Curitiba, Brazil; Bogotá, Colombia; and Cuernavaca, Mexico (2010-2011); is described to identify challenges for conducting PA and BE research in LA. Results Five challenges were identified: Lack of academic capacity (implemented solutions (IS): building a strong international collaborative network); limited data availability, access and quality (IS: partnering with influential local institutions, and crafting creative solutions to use the best-available data); socio-political, socio-cultural and socio-economic context (IS: in-person recruitment and data collection, alternative incentives); safety (IS: strict rules for data collection procedures, and specific measures to increase trust); appropriateness of instruments and measures (IS: survey adaptation, use of standardized additional survey components, and employing a context-based approach to understanding the relationship between PA and the BE). Advantages of conducting PA and BE research in LA were also identified. Conclusions Conducting high quality PA and BE research in LA is challenging but feasible. Networks of institutions and researchers from both HIC and LMIC play a key role. The lessons learnt from the IPEN LA study may be applicable to other LMIC. PMID:25456800

  8. Overcoming the challenges of conducting physical activity and built environment research in Latin America: IPEN Latin America.

    PubMed

    Salvo, Deborah; Reis, Rodrigo S; Sarmiento, Olga L; Pratt, Michael

    2014-12-01

    There is evidence linking the built environment (BE) with physical activity (PA), but few studies have been conducted in Latin America (LA). State-of-the-art methods and protocols have been designed in and applied in high-income countries (HIC). In this paper, we identify key challenges and potential solutions to conducting high-quality PA and BE research in LA. The experience of implementing the IPEN data collection protocol (IPEN: International Physical Activity Environment Network) in Curitiba, Brazil; Bogotá, Colombia; and Cuernavaca, Mexico (2010-2011); is described to identify challenges for conducting PA and BE research in LA. Five challenges were identified: lack of academic capacity (implemented solutions (IS): building a strong international collaborative network); limited data availability, access and quality (IS: partnering with influential local institutions, and crafting creative solutions to use the best-available data); socio-political, socio-cultural and socio-economic context (IS: in-person recruitment and data collection, alternative incentives); safety (IS: strict rules for data collection procedures, and specific measures to increase trust); and appropriateness of instruments and measures (IS: survey adaptation, use of standardized additional survey components, and employing a context-based approach to understanding the relationship between PA and the BE). Advantages of conducting PA and BE research in LA were also identified. Conducting high-quality PA and BE research in LA is challenging but feasible. Networks of institutions and researchers from both HIC and LMIC play a key role. The lessons learned from the IPEN LA study may be applicable to other LMIC. Copyright © 2014 Elsevier Inc. All rights reserved.

  9. Aeroservoelastic and Structural Dynamics Research on Smart Structures Conducted at NASA Langley Research Center

    NASA Technical Reports Server (NTRS)

    McGowan, Anna-Maria Rivas; Wilkie, W. Keats; Moses, Robert W.; Lake, Renee C.; Florance, Jennifer Pinkerton; Wieseman, Carol D.; Reaves, Mercedes C.; Taleghani, Barmac K.; Mirick, Paul H.; Wilbur, Mathew L.

    1997-01-01

    An overview of smart structures research currently underway at the NASA Langley Research Center in the areas of aeroservoelasticity and structural dynamics is presented. Analytical and experimental results, plans, potential technology pay-offs, and challenges are discussed. The goal of this research is to develop the enabling technologies to actively and passively control aircraft and rotorcraft vibration and loads using smart devices. These enabling technologies and related research efforts include developing experimentally-validated finite element and aeroservoelastic modeling techniques; conducting bench experimental tests to assess feasibility and understand system trade-offs; and conducting large-scale wind tunnel tests to demonstrate system performance. The key aeroservoelastic applications of this research include: active twist control of rotor blades using interdigitated electrode piezoelectric composites and active control of flutter, and gust and buffeting responses using discrete piezoelectric patches. In addition, NASA Langley is an active participant in the DARPA/Air Force Research Laboratory/NASA/Northrop Grumman Smart Wing program which is assessing aerodynamic performance benefits using smart materials.

  10. Aeroservoelastic and Structural Dynamics Research on Smart Structures Conducted at NASA Langley Research Center

    NASA Technical Reports Server (NTRS)

    McGowan, Anna-Maria Rivas; Wilkie, W. Keats; Moses, Robert W.; Lake, Renee C.; Florance, Jennifer Pinkerton; Wieseman, Carol D.; Reaves, Mercedes C.; Taleghani, Barmac K.; Mirick, Paul H.; Wilbur, Matthew L.

    1998-01-01

    An overview of smart structures research currently underway at the NASA Langley Research Center in the areas of aeroservoelasticity and structural dynamics is presented. Analytical and experimental results, plans, potential technology pay-offs, and challenges are discussed. The goal of this research is to develop the enabling technologies to actively and passively control aircraft and rotorcraft vibration and loads using smart devices. These enabling technologies and related research efforts include developing experimentally-validated finite element and aeroservoelastic modeling techniques; conducting bench experimental tests to assess feasibility and understand system trade-offs; and conducting large-scale wind- tunnel tests to demonstrate system performance. The key aeroservoelastic applications of this research include: active twist control of rotor blades using interdigitated electrode piezoelectric composites and active control of flutter, and gust and buffeting responses using discrete piezoelectric patches. In addition, NASA Langley is an active participant in the DARPA/ Air Force Research Laboratory/ NASA/ Northrop Grumman Smart Wing program which is assessing aerodynamic performance benefits using smart materials. Keywords: aeroelasticity, smart structures, piezoelectric actuators, active fiber composites, rotorcraft, buffet load alleviation, individual blade control, aeroservoelasticity, shape memory alloys, damping augmentation, piezoelectric power consumption

  11. Methodological factors conducting research with incarcerated persons with diabetes.

    PubMed

    Reagan, Louise; Shelton, Deborah

    2016-02-01

    The aim of this study was to describe methodological issues specific to conducting research with incarcerated vulnerable populations who have diabetes. Much has been written about the ethical and logistical challenges of conducting research with vulnerable incarcerated populations. However, conducting research with incarcerated persons with diabetes is associated with additional issues related to research design, measurement, sampling and recruitment, and data collection procedures. A cross-sectional study examining the relationships of diabetes knowledge, illness representation and self-care behaviors with glycemic control in 124 incarcerated persons was conducted and serves as the basis for describing methodological factors for the conduct of research with an incarcerated population with diabetes. Within this incarcerated population with diabetes, sampling bias due to gender inequity, recruitment of participants not using insulin, self-reported vision impairment, and a lack of standardized instruments especially for measuring diabetes self-care were methodological challenges. Clinical factors that serve as potential barriers for study conduct were identified as risk for hypoglycemia due to insulin timing and other activities. Conducting research with incarcerated persons diagnosed with diabetes requires attention to a set of methodological concerns above and beyond that of the ethical and legal regulations for protecting the rights of this vulnerable population. To increase opportunities for conducting rigorous as well as facility- and patient-friendly research, researchers need to blend their knowledge of diabetes with an understanding of prison rules and routines. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Conducting Rapid, Relevant Research

    PubMed Central

    Glasgow, Russell E.; Kessler, Rodger S.; Ory, Marcia G.; Roby, Dylan; Gorin, Sherri Sheinfeld; Krist, Alex

    2015-01-01

    The lengthy and uncertain translation of research into clinical practice is well documented. Much of the current “gold standard” clinical research is slow, expensive, and lacks perceived relevance for practitioners and decision makers. In contrast, we summarize experiences conducting the My Own Health Report (MOHR) project to collect and address patient reported measures using principles of rapid, relevant pragmatic research. The methods used for rapid design and fielding of the MOHR project to improve attention to health behaviors and mental health are detailed. Within the multisite, pragmatic, implementation–focused MOHR study, we describe the four phases of the research and the key decisions made and actions taken within each. We provide concrete examples of how relevant research can be conducted transparently to rapidly provide information to practitioners. Data were collected and analyzed in 2013. The multisite (seven research centers partnered with 18 clinics) cluster randomized pragmatic delayed intervention trial was conducted in less than 18 months from receipt of funding applications to completion of data collection. Phases that were especially accelerated included funding and review, and recruitment and implementation. Conducting complex studies rapidly and efficiently is a realistic goal. Key lessons learned for prevention research include: use of existing research networks; use of web-based assessment/feedback tools that are tailored to fit local needs; engaging relevant stakeholders early on and throughout the process to minimize need for redesign; and making pragmatic decisions that balance internal and external validity concerns rather than waiting for perfect solutions. PMID:24953520

  13. Conducting survey research at nursing conferences.

    PubMed

    Sleutel, M R

    2001-01-01

    Conferences can provide large numbers of potential subjects in one location, yet there is little published guidance on how to collect data at a conference site. A computer search revealed no citations on this topic. This article outlines a systematic strategy to plan and perform research at conferences. This article provides a step-by-step process to guide researchers in planning and conducting survey research at conferences. Initial components in planning data collection at a conference include making a timeline and getting permission. Detailed advanced planning involves specific strategies for attracting participants, and for distributing and collecting the questionnaires. Travel provisions and on-site logistical approaches are explained, followed by suggestions for post-conference activities.

  14. Using UAVs to Conduct Student-led Research Projects

    NASA Astrophysics Data System (ADS)

    Olds, S. E.; Lewis, P. M., Jr.

    2016-12-01

    Recreational drones can inspire students to initiate research projects. These "toys" have a low cost (<$100), low weight (< 250 g, so do not require FAA registration), and an ability to carry small instrument packages, making them an ideal platform for conducting innovative investigations. This session describes an initiative by the Federation of Earth Science Information Partners (ESIP) Education Committee to compile and distribute a free e-book that will encourage learners to use drones for science investigations. Our goal is to inspire learners to use UAVs to carry scientific instruments and/or capture imagery to conduct local-scale investigations. Experiments such as discovering their vehicle's maximum payload help learners understand what sensors they can use (or build) to conduct research. The e-book will encourage learners to practice UAV civility and safety through a pre-flight checklist and flying guidelines, and to consider science objectives and flight team roles in performing investigations. Activities also advocate for robust data and metadata-collection practices. Suggested activities encompass repeat photography investigations as well as engineering design skills such as designing a camera mount to obtain nadir or oblique imagery. Learners can also move to more sophisticated research using photogrammetric skills such as taking overlapping photographs to create 3D structure from motion (SfM) models. To encourage the use of onboard sensors, the team worked with an engineer to build a 33-gram prototype environmental logger called SABEL (Shelley [Olds] and Bob [Ellis]'s Environmental Logger). Assembled on an Arduino board, SABEL collects temperature, humidity, and GPS position. This presentation will provide examples of student-led investigations, instructions for building the SABEL sensor package, and the status of the new e-book compilation of student-focused activities using recreational drones to pursue science, math, engineering, and technology

  15. 34 CFR 350.32 - What activities must a Rehabilitation Engineering Research Center conduct?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false What activities must a Rehabilitation Engineering... DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM What Rehabilitation Engineering Research Centers Does the Secretary Assist? § 350.32 What activities must a Rehabilitation Engineering Research...

  16. 34 CFR 350.32 - What activities must a Rehabilitation Engineering Research Center conduct?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 2 2012-07-01 2012-07-01 false What activities must a Rehabilitation Engineering... DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM What Rehabilitation Engineering Research Centers Does the Secretary Assist? § 350.32 What activities must a Rehabilitation Engineering Research...

  17. 34 CFR 350.32 - What activities must a Rehabilitation Engineering Research Center conduct?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 2 2013-07-01 2013-07-01 false What activities must a Rehabilitation Engineering... DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM What Rehabilitation Engineering Research Centers Does the Secretary Assist? § 350.32 What activities must a Rehabilitation Engineering Research...

  18. 34 CFR 350.32 - What activities must a Rehabilitation Engineering Research Center conduct?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 2 2011-07-01 2010-07-01 true What activities must a Rehabilitation Engineering... DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM What Rehabilitation Engineering Research Centers Does the Secretary Assist? § 350.32 What activities must a Rehabilitation Engineering Research...

  19. 34 CFR 350.32 - What activities must a Rehabilitation Engineering Research Center conduct?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true What activities must a Rehabilitation Engineering... DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM What Rehabilitation Engineering Research Centers Does the Secretary Assist? § 350.32 What activities must a Rehabilitation Engineering Research...

  20. 30 CFR 280.21 - What must I do in conducting G&G prospecting or scientific research?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... scientific research? 280.21 Section 280.21 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... prospecting or scientific research? While conducting G&G prospecting or scientific research activities under a... you are prospecting or conducting scientific research activities. (b) Consult and coordinate your G&G...

  1. 30 CFR 280.11 - What must I do before I may conduct scientific research?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... I may conduct scientific research? You may conduct G&G scientific research activities related to... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What must I do before I may conduct scientific research? 280.11 Section 280.11 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND...

  2. Conducting Educational Design Research

    ERIC Educational Resources Information Center

    McKenney, Susan; Reeves, Thomas

    2012-01-01

    Educational design research blends scientific investigation with systematic development and implementation of solutions to educational problems. Empirical investigation is conducted in real learning settings--not laboratories--to craft usable and effective solutions. At the same time, the research is carefully structured to produce theoretical…

  3. Hypogravity Research and Educational Parabolic Flight Activities Conducted in Barcelona: a new Hub of Innovation in Europe

    NASA Astrophysics Data System (ADS)

    Perez-Poch, Antoni; González, Daniel Ventura; López, David

    2016-12-01

    We report on different research and educational activities related to parabolic flights conducted in Barcelona since 2008. We use a CAP10B single-engine aerobatic aircraft flying out of Sabadell Airport and operating in visual flight conditions providing up to 8 seconds of hypogravity for each parabola. Aside from biomedical experiments being conducted, different student teams have flown in parabolic flights in the framework of the international contest `Barcelona Zero-G Challenge', and have published their results in relevant symposiums and scientific journals. The platform can certainly be a good testbed for a proof-of-concept before accessing other microgravity platforms, and has proved to be excellent for motivational student campaigns.

  4. Conducting international nursing research: challenges and opportunities.

    PubMed

    Opollo, Jackline Gloria; Opollo, Diana Alaka; Gray, Jennifer; Spies, Lori

    2014-11-01

    To describe practical experiences before, during and after gaining entry into research fields in Kenya and Uganda. Planning, conducting and implementing international research can be an arduous task. Novice researchers need practical guides to accessing international fields and mitigating challenges met in the field. The researchers conducted three different studies in two developing nations. This paper reviews challenges encountered when conducting international research. Solutions used to overcome these challenges are discussed. Establishing and maintaining effective partnerships is critical to the success of international research efforts. Researchers must be tactful, flexible and creative when handling methodological, ethical and logistical challenges encountered in settings poor in resources. International research provides opportunities for increasing dedication, building cross-cultural competence and advancing health professional practice globally. This paper contributes to nursing scholarship by highlighting the practical challenges of conducting international research. Illustrations aimed at lending insight and encouraging others to expand their dedication to conducting international research are offered.

  5. Benefits of Conducting Research.

    ERIC Educational Resources Information Center

    Anderson, Frances E.

    2001-01-01

    Metaphors for researchers, such as a crusader; a traveler; an explorer; a miner; an astronaut; a biblical Daniel; a Samurai; and an archaeologist are discussed. Benefits of conducting research are enumerated, including building the knowledge base for art therapy; increasing professional opportunities; improving client care; and advancing the…

  6. Research Trends of Soft Actuators based on Electroactive Polymers and Conducting Polymers

    NASA Astrophysics Data System (ADS)

    Kaneto, K.

    2016-04-01

    Artificial muscles (or soft actuators) based on electroactive polymers (EAPs) are attractive power sources to drive human-like robots in place of electrical motor, because they are quiet, powerful, light weight and compact. Among EAPs for soft actuators, conducting polymers are superior in strain, stress, deformation form and driving voltage compared with the other EAPs. In this paper, the research trends of EAPs and conducting polymers are reviewed by retrieval of the papers and patents. The research activity of EAP actuators showed the maximum around 2010 and somehow declining now days. The reasons for the reducing activity are found to be partly due to problems of conducting polymer actuators for the practical application. The unique characteristics of conducting polymer actuators are mentioned in terms of the basic mechanisms of actuation, creeping, training effect and shape retention under high tensile loads. The issues and limitation of conducting polymer soft actuators are discussed.

  7. 38 CFR 1.488 - Research activities.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2012-07-01 2012-07-01 false Research activities. 1... PROVISIONS Disclosures Without Patient Consent § 1.488 Research activities. Subject to the provisions of 38 U... disclosed for the purpose of conducting scientific research. (a) Information in individually identifiable...

  8. 38 CFR 1.488 - Research activities.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Research activities. 1... PROVISIONS Disclosures Without Patient Consent § 1.488 Research activities. Subject to the provisions of 38 U... disclosed for the purpose of conducting scientific research. (a) Information in individually identifiable...

  9. 38 CFR 1.488 - Research activities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Research activities. 1... PROVISIONS Disclosures Without Patient Consent § 1.488 Research activities. Subject to the provisions of 38 U... disclosed for the purpose of conducting scientific research. (a) Information in individually identifiable...

  10. 38 CFR 1.488 - Research activities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Research activities. 1... PROVISIONS Disclosures Without Patient Consent § 1.488 Research activities. Subject to the provisions of 38 U... disclosed for the purpose of conducting scientific research. (a) Information in individually identifiable...

  11. 38 CFR 1.488 - Research activities.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Research activities. 1... PROVISIONS Disclosures Without Patient Consent § 1.488 Research activities. Subject to the provisions of 38 U... disclosed for the purpose of conducting scientific research. (a) Information in individually identifiable...

  12. Community Interactive Research Workshop Series: Community Members Engaged as Team Teachers to Conduct Research.

    PubMed

    Nguyen-Truong, Connie Kim; Tang, Joannie; Hsiao, Chiao-Yun

    2017-01-01

    Vietnamese women are diagnosed with cervical cancer at twice the rate of non-Hispanic White women and the highest compared to Chinese, Filipino, Korean, and Japanese women. ἀ e Vietnamese Women's Health Project, a community-based participatory research partnership, was developed to address this concern. In earlier studies, community members received research training. To describe how we developed an innovative curricular research training framework. Community members developed their own learning goals and activities, taught alongside a nurse scientist, and participated in a community interactive research workshop series. Popular education principles were used to guide team teaching. Topics, learning goals, lesson plans, and an evaluation w ere de veloped t ogether. ἀ ree, 4 -5.5 h our workshops were hosted. Topics included qualitative research, art of hearing data, reflexivity, analysis, validity, and dissemination. Community members and a nurse scientist co-constructed knowledge through participatory methods. ἀe workshops ran concurrent to the study timeline to inform community members' research activities and vice versa. A range from 8 to 20 participants attended the workshops, of which six community members were team teachers and three facilitated at each workshop. In an evaluation, team teachers reported workshop strengths: an empathetic and trusting learn ing environment, a sense of ownership in learning, a greater under standing of roles in research partnerships, and a feel ing of safety to conduct research with academic investigators. Academic investigators need to be aware that co-constructing knowledge is foundational to long-term sustainability of community-based participatory research partnership (CBPR) partnerships, but requires building team capacity to conduct research collaboratively.

  13. Conducting Research With Community Groups.

    PubMed

    Doornbos, Mary Molewyk; Ayoola, Adejoke; Topp, Robert; Zandee, Gail Landheer

    2015-10-01

    Nurse scientists are increasingly recognizing the necessity of conducting research with community groups to effectively address complex health problems and successfully translate scientific advancements into the community. Although several barriers to conducting research with community groups exist, community-based participatory research (CBPR) has the potential to mitigate these barriers. CBPR has been employed in programs of research that respond in culturally sensitive ways to identify community needs and thereby address current health disparities. This article presents case studies that demonstrate how CBPR principles guided the development of (a) a healthy body weight program for urban, underserved African American women; (b) a reproductive health educational intervention for urban, low-income, underserved, ethnically diverse women; and (c) a pilot anxiety/depression intervention for urban, low-income, underserved, ethnically diverse women. These case studies illustrate the potential of CBPR as an orientation to research that can be employed effectively in non-research-intensive academic environments. © The Author(s) 2015.

  14. Conducting Research with Community Groups

    PubMed Central

    Doornbos, Mary Molewyk; Ayoola, Adejoke; Topp, Robert; Zandee, Gail Landheer

    2016-01-01

    Nurse scientists are increasingly recognizing the necessity of conducting research with community groups to effectively address complex health problems and successfully translate scientific advancements into the community. While several barriers to conducting research with community groups exist, community based participatory research (CBPR) has the potential to mitigate these barriers. CBPR has been employed in programs of research that respond in culturally sensitive ways to identify community needs and thereby address current health disparities. This manuscript presents case studies that demonstrate how CBPR principles guided the development of: (a) a healthy body weight program for urban, underserved African-American women, (b) a reproductive health educational intervention for urban, low-income, underserved, ethnically diverse women, and (c) a pilot anxiety/depression intervention for urban, low-income, underserved, ethnically diverse women. These case studies illustrate the potential of CBPR as an orientation to research that can be employed effectively in non-research intensive academic environments. PMID:25724557

  15. 30 CFR 280.11 - What must I do before I may conduct scientific research?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Apply for a Permit or File a Notice § 280.11 What must I do before I may conduct scientific research? You may conduct G&G scientific research activities related to hard minerals on the OCS only after you... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I do before I may conduct scientific...

  16. 34 CFR 350.22 - What activities must a Rehabilitation Research and Training Center conduct?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... individuals with disabilities, through conferences, workshops, public education programs, in-service training... Training Center conduct? 350.22 Section 350.22 Education Regulations of the Offices of the Department of... DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM What Rehabilitation Research and Training...

  17. 34 CFR 350.22 - What activities must a Rehabilitation Research and Training Center conduct?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... individuals with disabilities, through conferences, workshops, public education programs, in-service training... Training Center conduct? 350.22 Section 350.22 Education Regulations of the Offices of the Department of... DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM What Rehabilitation Research and Training...

  18. 34 CFR 350.22 - What activities must a Rehabilitation Research and Training Center conduct?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... individuals with disabilities, through conferences, workshops, public education programs, in-service training... Training Center conduct? 350.22 Section 350.22 Education Regulations of the Offices of the Department of... DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM What Rehabilitation Research and Training...

  19. 34 CFR 350.22 - What activities must a Rehabilitation Research and Training Center conduct?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... individuals with disabilities, through conferences, workshops, public education programs, in-service training... Training Center conduct? 350.22 Section 350.22 Education Regulations of the Offices of the Department of... DISABILITY AND REHABILITATION RESEARCH PROJECTS AND CENTERS PROGRAM What Rehabilitation Research and Training...

  20. Conducting Research in School Systems.

    ERIC Educational Resources Information Center

    Schutz, Richard E.

    The problems of conducting research in schools are discussed. Solutions to social psychological problems are suggested, and an improved design for research is recommended. Clearer definition of terminology is recommended to avoid the confusion that can result from ambiguous terms. A research design should be adaptable to the administrative and…

  1. Research-active clinical nurses: against all odds.

    PubMed

    Siedlecki, Sandra L; Albert, Nancy M

    2017-03-01

    To develop a theoretical understanding of factors that impact decisions of clinical nurses to conduct a research study. Only a small percentage of all nurses are research-active and even fewer clinical nurses are research-active. Several researchers have explored barriers to research activity by clinical nurses, but few have examined why, in spite of all odds, some clinical nurses are research-active. As the purpose of this study was to develop a theoretical understanding of the research-active nurse, a grounded theory approach was used. The sample interviewed for this study consisted of registered nurses (n = 26) who worked in a hospital or ambulatory setting, had daily direct patient contact and had participated as principal investigator on at least one completed clinical nursing research study that was not in fulfilment of an educational requirement. The interviews were digitally recorded and analysed by two researchers using the constant comparative method. The findings from this study suggest that the conduct of research by clinical nurses was the direct result of a clinical trigger, characteristics and beliefs of the nurse about research and their role in generating knowledge, and the presence of support conditions, such as a research mentor. Clinical nurses can and do conduct research, in spite of constraints due to a lack of time, money and/or knowledge, if they have access to research mentors and are practising in a research-supportive environment. Nurses at the bedside are in a unique position to identify problems most in need of solutions. Findings from this study provide a foundation upon which to develop and test various programmes that seek to increase the number of clinical nurses who are research-active. © 2016 John Wiley & Sons Ltd.

  2. 40 CFR 725.239 - Use of specific microorganisms in activities conducted outside a structure.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... activities conducted outside a structure. 725.239 Section 725.239 Protection of Environment ENVIRONMENTAL... MICROORGANISMS Exemptions for Research and Development Activities § 725.239 Use of specific microorganisms in activities conducted outside a structure. (a) Bradyrhizobium japonicum. To qualify for an exemption under...

  3. 40 CFR 725.239 - Use of specific microorganisms in activities conducted outside a structure.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... activities conducted outside a structure. 725.239 Section 725.239 Protection of Environment ENVIRONMENTAL... MICROORGANISMS Exemptions for Research and Development Activities § 725.239 Use of specific microorganisms in activities conducted outside a structure. (a) Bradyrhizobium japonicum. To qualify for an exemption under...

  4. Bone Conduction Communication: Research Progress and Directions

    DTIC Science & Technology

    2017-08-16

    ARL-TR-8096 ● AUG 2017 US Army Research Laboratory Bone Conduction Communication: Research Progress and Directions by Maranda...this report when it is no longer needed. Do not return it to the originator. ARL-TR-8096 ● AUG 2017 US Army Research Laboratory...Bone Conduction Communication: Research Progress and Directions by Maranda McBride North Carolina Agricultural and Technical State University

  5. How to Conduct Ethnographic Research

    ERIC Educational Resources Information Center

    Sangasubana, Nisaratana

    2011-01-01

    The purpose of this paper is to describe the process of conducting ethnographic research. Methodology definition and key characteristics are given. The stages of the research process are described including preparation, data gathering and recording, and analysis. Important issues such as reliability and validity are also discussed.

  6. Operational readiness for conducting global health research abroad.

    PubMed

    McDonald, Judy M; Gyorkos, Theresa W

    2016-12-27

    Research excellence is the goal of all researchers. Conducting quality research with the ultimate aim of improving health is a shared goal among researchers in the global health domain. The competencies required for conducting and producing quality research in global health go far beyond the academic or scientific spheres. They incorporate aspects of research partnership, which places humility, empathy, and mutual respect at its core. Conducting quality respectful global health research requires an appropriate balance of operational readiness (i.e., technical, physical, and mental readiness). This paper reports on the pertinence and potential shaping of conceptual work and exploratory research focusing on aspects of mental readiness. These aspects may be perceived to be significant enough to influence success and warrant further investigation in the context of conducting global health research abroad.

  7. Research Politics: Some Issues in Conducting Research for Government as a Client

    ERIC Educational Resources Information Center

    Diko, Nolutho; Bantwini, Bongani D.

    2013-01-01

    Researchers are guided by their ideological and ethical viewpoints when conducting research. Doing research for government challenges them to confront these ideals head-on. This article explores the uncertain terrain researchers sometimes have to negotiate when conducting research for government, and discusses relations between researchers and…

  8. Feasibility of Conducting Autism Biomarker Research in the Clinical Setting.

    PubMed

    Sices, Laura; Pawlowski, Katherine; Farfel, Laura; Phillips, Deirdre; Howe, Yamini; Cochran, David M; Choueiri, Roula; Forbes, Peter W; Brewster, Stephanie J; Frazier, Jean A; Neumeyer, Ann; Bridgemohan, Carolyn

    2017-09-01

    Recruitment and completion of research activities during regular clinical care has the potential to increase research participation in complex neurodevelopmental disorders. We evaluated the feasibility, and effect on clinical care, of conducting biomarker research within a subspecialty clinical visit for autism spectrum disorder (ASD). Children, aged 5 to 10 years, were recruited by providers in ASD clinics at 5 institutions. Biomarkers collected were growth measurements, head circumference, neurologic and dysmorphology examinations, digit ratio (2D:4D) measurement, and platelet serotonin and urinary melatonin sulfate excretion levels. Parents completed the Aberrant Behavior Checklist-Community and a medical/demographic questionnaire. Cognitive level was abstracted from the medical record. Parents and clinicians completed surveys on the effect of the study on the clinical visit. Eighty-three children and their caregivers participated. Factors limiting participation included difficulty reaching families by phone and parent concern about the study blood draw requirement. All children completed at least 4 of 7 planned research activities. Demographic factors, educational placement, and child behavior were not associated with completion of study activities. Lower nonverbal cognitive function was weakly associated with fewer activities completed. Forty-four percent of clinicians reported an effect of the research study on the clinical visit. However, neither parent-reported nor clinician-reported effect was associated with the degree of study activity completion. Recruiting study participants in the context of scheduled ASD clinical visits required significant effort. However, once recruited, participants completed most study activities, regardless of behavioral symptom severity. Research activities did not adversely affect the clinical visit.

  9. Ten steps to conducting health professional education research.

    PubMed

    Scott, Karen; Caldwell, Patrina; Schuwirth, Lambert

    2015-08-01

    The approaches used to educate future clinicians must be continually improved through evidence-based methods. Clinicians interested in conducting education research need to understand the terminology and conventions of health professional education, in the same way that health professional educators from education backgrounds need to be aware of clinical practices and scientific mores and jargon. This article provides clinicians with 10 steps to conducting health professional education research, and encourages collaboration between clinicians interested in education and health professional educators. The basic steps in conducting education research are introduced, beginning with literature searches, using appropriate terminology and writing conventions, and finding research collaborators. We encourage researchers to ask themselves, 'So what?' about their research idea to ensure it is interesting and relevant to a journal's readers. The nuts and bolts of educational research are then presented, including research questions and methodologies, outcome measures, theoretical frameworks and epistemologies. The final two steps aim to foster internationally relevant and well-designed research studies. Conducting and publishing education research is often difficult for clinicians, who struggle with what is required. Yet clinicians who teach are ideally placed to identify the knowledge gaps about how we can more effectively educate future clinicians. These 10 steps provide clinicians with guidance on how to conduct education research so relevant research findings can inform the education of future clinicians. Conducting and publishing education research is often difficult for clinicians. © 2015 John Wiley & Sons Ltd.

  10. A consensus statement on how to conduct inclusive health research.

    PubMed

    Frankena, T K; Naaldenberg, J; Cardol, M; Garcia Iriarte, E; Buchner, T; Brooker, K; Embregts, P; Joosa, E; Crowther, F; Fudge Schormans, A; Schippers, A; Walmsley, J; O'Brien, P; Linehan, C; Northway, R; van Schrojenstein Lantman-de Valk, H; Leusink, G

    2018-04-11

    The active involvement of people with intellectual disabilities in research, or inclusive research, is relatively common. However, inclusive health research is less common, even though it is expected to lead to appropriate healthcare and increased quality of life. Inclusive health research can build upon lessons learned from inclusive research. A total of 17 experts on inclusive (health) research without intellectual disabilities and 40 experts with intellectual disabilities collaborated in this consensus statement. The consensus statement was developed in three consecutive rounds: (1) an initial feedback round; (2) a roundtable discussion at the 2016 International Association for the Scientific Study of Intellectual and Developmental Disabilities World Congress; and (3) a final feedback round. This consensus statement provides researchers with guidelines, agreed upon by experts in the field, regarding attributes, potential outcomes, reporting and publishing, and future research directions, for designing and conducting inclusive health research. Consensus was reached on how to design and conduct inclusive health research. However, this statement should be continuously adapted to incorporate recent knowledge. The focus of this consensus statement is largely on inclusive health research, but the principles can also be applied to other areas. © 2018 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  11. How Work Positions Affect the Research Activity and Information Behaviour of Laboratory Scientists in the Research Lifecycle: Applying Activity Theory

    ERIC Educational Resources Information Center

    Kwon, Nahyun

    2017-01-01

    Introduction: This study was conducted to investigate the characteristics of research and information activities of laboratory scientists in different work positions throughout a research lifecycle. Activity theory was applied as the conceptual and analytical framework. Method: Taking a qualitative research approach, in-depth interviews and field…

  12. A Counsellor's Guide to Conducting Psychobiographical Research

    ERIC Educational Resources Information Center

    Ponterotto, Joseph G.

    2017-01-01

    By nature of their interests and professional training, counsellors are ideally equipped to conduct psychobiographical research. This article positions the counselling field in the broad specialty area of psychobiography, highlights the preparedness of counsellors to conduct psychobiographical research, and emphasizes the benefits of this research…

  13. Participatory Action Research as a Model for Conducting Family Research.

    ERIC Educational Resources Information Center

    Turnbull, Ann P.; Friesen, Barbara J.; Ramirez, Carmen

    1998-01-01

    This article discusses a participatory action research (PAR) approach to conducting family research. It proposes a model of PAR implementation level including the options of family members as research leaders and researchers as ongoing advisors, researchers and family members as coresearchers, and researches as leaders, and family members as…

  14. 30 CFR 280.21 - What must I do in conducting G&G prospecting or scientific research?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... scientific research? 280.21 Section 280.21 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION... What must I do in conducting G&G prospecting or scientific research? While conducting G&G prospecting or scientific research activities under a permit or notice, you must: (a) Immediately report to the...

  15. An Integrated Extravehicular Activity Research Plan

    NASA Technical Reports Server (NTRS)

    Abercromby, Andrew F. J.; Ross, Amy J.; Cupples, J. Scott

    2016-01-01

    Multiple organizations within NASA and outside of NASA fund and participate in research related to extravehicular activity (EVA). In October 2015, representatives of the EVA Office, the Crew and Thermal Systems Division (CTSD), and the Human Research Program (HRP) at NASA Johnson Space Center agreed on a formal framework to improve multi-year coordination and collaboration in EVA research. At the core of the framework is an Integrated EVA Research Plan and a process by which it will be annually reviewed and updated. The over-arching objective of the collaborative framework is to conduct multi-disciplinary cost-effective research that will enable humans to perform EVAs safely, effectively, comfortably, and efficiently, as needed to enable and enhance human space exploration missions. Research activities must be defined, prioritized, planned and executed to comprehensively address the right questions, avoid duplication, leverage other complementary activities where possible, and ultimately provide actionable evidence-based results in time to inform subsequent tests, developments and/or research activities. Representation of all appropriate stakeholders in the definition, prioritization, planning and execution of research activities is essential to accomplishing the over-arching objective. A formal review of the Integrated EVA Research Plan will be conducted annually. External peer review of all HRP EVA research activities including compilation and review of published literature in the EVA Evidence Book is already performed annually. Coordination with stakeholders outside of the EVA Office, CTSD, and HRP is already in effect on a study-by-study basis; closer coordination on multi-year planning with other EVA stakeholders including academia is being actively pursued. Details of the current Integrated EVA Research Plan are presented including description of ongoing and planned research activities in the areas of: Benchmarking; Anthropometry and Suit Fit; Sensors; Human

  16. Conducting research in clinical psychology practice: Barriers, facilitators, and recommendations.

    PubMed

    Smith, Kirsten V; Thew, Graham R

    2017-09-01

    The combination of clinical psychologists' therapeutic expertise and research training means that they are in an ideal position to be conducting high-quality research projects. However, despite these skills and the documented benefits of research to services and service users, research activity in practice remains low. This article aims to give an overview of the advantages of, and difficulties in conducting research in clinical practice. We reviewed the relevant literature on barriers to research and reflected on our clinical and research experiences in a range of contexts to offer practical recommendations. We considered factors involved in the planning, sourcing support, implementation, and dissemination phases of research, and outline suggestions to improve the feasibility of research projects in post-qualification roles. We suggest that research leadership is particularly important within clinical psychology to ensure the profession's continued visibility and influence within health settings. Clinical implications Emerging evidence suggests that clinical settings that foster research are associated with better patient outcomes. Suggestions to increase the feasibility of research projects in clinical settings are detailed. Limitations The present recommendations are drawn from the authors' practical experience and may need adaptation to individual practitioners' settings. This study does not attempt to assess the efficacy of the strategies suggested. © 2017 The Authors. British Journal of Clinical Psychology published by John Wiley & Sons Ltd on behalf of British Psychological Society.

  17. Integrated Extravehicular Activity Human Research Plan: 2017

    NASA Technical Reports Server (NTRS)

    Abercromby, Andrew

    2017-01-01

    Multiple organizations within NASA as well as industry and academia fund and participate in research related to extravehicular activity (EVA). In October 2015, representatives of the EVA Office, the Crew and Thermal Systems Division (CTSD), and the Human Research Program (HRP) at NASA Johnson Space Center agreed on a formal framework to improve multi-year coordination and collaboration in EVA research. At the core of the framework is an Integrated EVA Human Research Plan and a process by which it will be annually reviewed and updated. The over-arching objective of the collaborative framework is to conduct multi-disciplinary cost-effective research that will enable humans to perform EVAs safely, effectively, comfortably, and efficiently, as needed to enable and enhance human space exploration missions. Research activities must be defined, prioritized, planned and executed to comprehensively address the right questions, avoid duplication, leverage other complementary activities where possible, and ultimately provide actionable evidence-based results in time to inform subsequent tests, developments and/or research activities. Representation of all appropriate stakeholders in the definition, prioritization, planning and execution of research activities is essential to accomplishing the over-arching objective. A formal review of the Integrated EVA Human Research Plan will be conducted annually. Coordination with stakeholders outside of the EVA Office, CTSD, and HRP is already in effect on a study-by-study basis; closer coordination on multi-year planning with other EVA stakeholders including academia is being actively pursued. Details of the preliminary Integrated EVA Human Research Plan are presented including description of ongoing and planned research activities in the areas of: physiological and performance capabilities; suit design parameters; EVA human health and performance modeling; EVA tasks and concepts of operations; EVA informatics; human-suit sensors; suit

  18. Research challenges and lessons learned from conducting community-based research with the Hmong community.

    PubMed

    Kue, Jennifer; Thorburn, Sheryl; Keon, Karen Levy

    2015-05-01

    Conducting research with underserved communities with little exposure to research presents a number of challenges and opportunities. Our study used a community-based approach to better understand factors that influence breast and cervical cancer screening among Hmong women. This article shares lessons learned during the process of developing and conducting qualitative research with a Hmong community with limited experience with research. We conducted 17 key informant and 84 in-depth interviews with Hmong women and men. Research team discussions, insights from Hmong research team members, input from our Community Advisory Committee, and project documents were sources of information about the process of conducting research in this community. Lessons learned concern including a cultural insider as an investigator; building community partnerships and support; establishing and working with a community advisory committee; hiring and training bilingual, bicultural staff; and using culturally appropriate materials and methods in a small, kinship-based community. We used multiple strategies to ensure that this study was conducted in a culturally appropriate manner. The lessons learned from our experiences can provide guidance to researchers on methodological and practical issues in conducting research with the Hmong and can inform future research with the Hmong and other similar underserved populations. © 2014 Society for Public Health Education.

  19. Bioethical Issues in Conducting Pediatric Dentistry Clinical Research.

    PubMed

    Garrocho-Rangel, Arturo; Cerda-Cristerna, Bernardino; Pozos-Guillen, Amaury

    Pediatric clinical research on new drugs and biomaterials involves children in order to create valid and generalizable knowledge. Research on vulnerable populations, such as children, is necessary but only admissible when researchers strictly follow methodological and ethical standards, together with the respect to human rights; and very especially when the investigation cannot be conducted with other population or when the potential benefits are specifically for that age group. Clinical research in Pediatric Dentistry is not an exception. The aim of the present article was to provide the bioethical principles (with respect to the child/parents' autonomy, benefit/risk analysis, and distributive justice), and recommendations, including informed consent, research ethics committees, conflict of interest, and the "equipoise" concept. Current and future worldwide oral health research in children and adolescents must be conducted incorporating their perspectives in the decision-making process as completely as possible. This concept must be carefully considered when a dental clinical study research is going to be planned and conducted, especially in the case of randomized controlled trials, in which children will be recruited as participants.

  20. Conducting qualitative research in audiology: a tutorial.

    PubMed

    Knudsen, Line V; Laplante-Lévesque, Ariane; Jones, Lesley; Preminger, Jill E; Nielsen, Claus; Lunner, Thomas; Hickson, Louise; Naylor, Graham; Kramer, Sophia E

    2012-02-01

    Qualitative research methodologies are being used more frequently in audiology as it allows for a better understanding of the perspectives of people with hearing impairment. This article describes why and how international interdisciplinary qualitative research can be conducted. This paper is based on a literature review and our recent experience with the conduction of an international interdisciplinary qualitative study in audiology. We describe some available qualitative methods for sampling, data collection, and analysis and we discuss the rationale for choosing particular methods. The focus is on four approaches which have all previously been applied to audiologic research: grounded theory, interpretative phenomenological analysis, conversational analysis, and qualitative content analysis. This article provides a review of methodological issues useful for those designing qualitative research projects in audiology or needing assistance in the interpretation of qualitative literature.

  1. Who Is Conducting Teacher Research?

    ERIC Educational Resources Information Center

    Hahs-Vaughn, Debbie L.; Yanowitz, Karen L.

    2009-01-01

    Few researchers have gone beyond case studies to examine characteristics of teachers who engage in research activities. Results from the authors' logistic regression models provide evidence that teaching in private schools, teaching in a midsize or large city, participating in professional development programs, and receiving support from the…

  2. Confounding adjustment in comparative effectiveness research conducted within distributed research networks.

    PubMed

    Toh, Sengwee; Gagne, Joshua J; Rassen, Jeremy A; Fireman, Bruce H; Kulldorff, Martin; Brown, Jeffrey S

    2013-08-01

    A distributed research network (DRN) of electronic health care databases, in which data reside behind the firewall of each data partner, can support a wide range of comparative effectiveness research (CER) activities. An essential component of a fully functional DRN is the capability to perform robust statistical analyses to produce valid, actionable evidence without compromising patient privacy, data security, or proprietary interests. We describe the strengths and limitations of different confounding adjustment approaches that can be considered in observational CER studies conducted within DRNs, and the theoretical and practical issues to consider when selecting among them in various study settings. Several methods can be used to adjust for multiple confounders simultaneously, either as individual covariates or as confounder summary scores (eg, propensity scores and disease risk scores), including: (1) centralized analysis of patient-level data, (2) case-centered logistic regression of risk set data, (3) stratified or matched analysis of aggregated data, (4) distributed regression analysis, and (5) meta-analysis of site-specific effect estimates. These methods require different granularities of information be shared across sites and afford investigators different levels of analytic flexibility. DRNs are growing in use and sharing of highly detailed patient-level information is not always feasible in DRNs. Methods that incorporate confounder summary scores allow investigators to adjust for a large number of confounding factors without the need to transfer potentially identifiable information in DRNs. They have the potential to let investigators perform many analyses traditionally conducted through a centralized dataset with detailed patient-level information.

  3. 7 CFR 3400.21 - Scientific peer review for research activities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 15 2011-01-01 2011-01-01 false Scientific peer review for research activities. 3400... § 3400.21 Scientific peer review for research activities. Scientific peer review is an evaluation of a... with the scientific knowledge and technical skills to conduct the proposed research work. Peer...

  4. Conducting transcultural research: critical thinking in Thailand.

    PubMed

    Jenkins, Sheryl D

    2011-01-01

    Little has been written to help researchers prepare for the unique challenges of conducting transcultural research. The purpose of this article is to discuss issues that arose during the planning and execution of a transcultural study designed to compare critical thinking in Thailand and the United States. The challenges of identifying a research site, selecting participants, incorporating Thai research into the literature review, traveling and living in a foreign culture, overcoming cultural barriers to research, and strengthening internal validity and reliability are addressed.

  5. Technology Commercialization Effects on the Conduct of Research in Higher Education

    PubMed Central

    Powers, Joshua B.; Campbell, Eric G.

    2012-01-01

    The objective of this study was to investigate the effects of technology commercialization on researcher practice and productivity at U.S. universities. Using data drawn from licensing contract documents and databases of university-industry linkages and faculty research output, the study findings suggest that the common practice of licensing technologies exclusively to singular firms may have a dampening effect on faculty inventor propensity to conduct published research and to collaborate with others on research. Furthermore, faculty who are more actively engaged in patenting may be less likely to collaborate with outsiders on research while faculty at public universities may experience particularly strong norms to engage in commercialization vis-à-vis traditional routes to research dissemination. These circumstances appear to be hindering innovation via the traditional mechanisms (research publication and collaboration), questioning the success of policymaking to date for the purpose of speeding the movement of research from the lab bench to society. PMID:22427717

  6. 48 CFR 32.202-3 - Conducting market research about financing terms.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Conducting market research... 32.202-3 Conducting market research about financing terms. Contract financing may be a subject included in the market research conducted in accordance with part 10. If market research for contract...

  7. 48 CFR 32.202-3 - Conducting market research about financing terms.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Conducting market research... 32.202-3 Conducting market research about financing terms. Contract financing may be a subject included in the market research conducted in accordance with part 10. If market research for contract...

  8. Clinical Nurse Specialist Roles in Conducting Research: Changes Over 3 Years.

    PubMed

    Albert, Nancy M; Rice, Karen L; Waldo, Mary J; Bena, James F; Mayo, Ann M; Morrison, Shannon L; Westlake, Cheryl; Ellstrom, Kathleen; Powers, Jan; Foster, Jan

    2016-01-01

    The aim of this study is to describe clinical nurse specialists' characteristics, interest, confidence, motivators, and barriers in conducting research. This study was a descriptive, multicohort design. Clinical nurse specialists were recruited electronically through national and local organizations to complete anonymous surveys 3 times, over 3 years. Comparative analyses included χ and Kruskal-Wallis tests. Of 2052 responders (initial, n = 629; 18 months, n = 465; and 3 years, n = 958), mean (SD) participant age was 50.3 (9.3) years. Overall, 41.7% of participants were involved as principal or coinvestigators in research. Interest in conducting nursing research (on a 0-100 scale) was 61.1 (38.4) and was lowest among the 18-month time point participant group (score, 39.1 [32.2]) and highest at the 3-year time point (68.3, [30.7]; P < .001). Confidence in conducting research, discussion of statistics, and perceptions of motivators and barriers to conducting research did not differ across time period groups. Access to literature and mentors and research knowledge were the most prevalent barriers to conducting research. Less than 42% of clinical nurse specialists conducted research and the rate did not change between different time groups. Access and knowledge barriers to conducting research were prominent. Workplace leaders need to consider resources and support of academic educational opportunities to increase research conduct by clinical nurse specialists.

  9. Challenges in conducting research in pediatric long-term care facilities.

    PubMed

    Larson, Elaine L; Cohen, Bevin; Murray, Meghan; Saiman, Lisa

    2014-10-01

    Children residing in long-term care facilities (LTCFs) have complex medical problems and unique care needs, yet research in this setting is rare. As part of an intervention study to improve patient safety (Keep It Clean for Kids [KICK]), we describe the challenges encountered and recommend approaches to build a successful and sustained collaborative relationship between pediatric LTCFs and the research team. We implemented a program with 5 components: leadership commitment, active staff participation by the creation of KICK teams, workflow assessments, staff training in the World Health Organization's "5 Moments for Hand Hygiene," and electronic monitoring and feedback to staff regarding hand hygiene practices. Major challenges encountered were establishing trust, building research teams, enhancing staff participation, and engaging families and visitors. Approaches to deal with these challenges are discussed. Conducting research in pediatric LTCFs requires sustained commitment to dealing with challenges and establishing collaborative relationships with administrative and frontline staff. © The Author(s) 2014.

  10. Conducting Science-Based Psychology Research in Schools

    ERIC Educational Resources Information Center

    Dinella, Lisa M., Ed.

    2009-01-01

    What are the common pitfalls experienced by school researchers and how can they be avoided? Edited by Lisa M. Dinella of Monmouth University, "Conducting Science-Based Psychology Research in Schools" includes the collective knowledge of both established and emerging names in the field, providing an unparalleled resource for those interested in…

  11. Conducting Research in Schools: A Practical Guide

    ERIC Educational Resources Information Center

    Alibali, Martha W.; Nathan, Mitchell J.

    2010-01-01

    Cognitive development unfolds in many contexts, and one of the most important of these contexts is school. Thus, understanding the school context is critical for understanding development. This article discusses some of the reasons why cognitive developmental researchers might wish to conduct research in schools, describes how to get started…

  12. Conducting On-Farm Animal Research: Procedures & Economic Analysis.

    ERIC Educational Resources Information Center

    Amir, Pervaiz; Knipscheer, Hendrik C.

    This book is intended to give animal scientists elementary tools to perform on-farm livestock analysis and to provide crop-oriented farming systems researchers with methods for conducting animal research. Chapter 1 describes farming systems research as a systems approach to on-farm animal research. Chapter 2 outlines some important…

  13. Considerations when conducting e-Delphi research: a case study.

    PubMed

    Toronto, Coleen

    2017-06-22

    Background E-Delphi is a way to access a geographically dispersed group of experts. It is similar to other Delphi methods but conducted online. E-research methodologies, such as the e-Delphi method, have yet to undergo significant critical discussion. Aim To highlight some of the challenges nurse researchers may wish to consider when using e-Delphi in their research. Discussion This paper provides details about the author's approach to conducting an e-Delphi study in which a group of health literacy nurse experts (n=41) used an online survey platform to identify and prioritise essential health literacy competencies for registered nurses. Conclusion This paper advances methodological discourse about e-Delphi by critically assessing an e-Delphi case study. The online survey platform used in this study was advantageous for the researcher and the experts: the experts could participate at any time and place where the internet was available; the researcher could efficiently access a national group of experts, track responses and analyse data in each round. Implications for practice E-Delphi studies create opportunities for nurse researchers to conduct research nationally and internationally. Before conducting an e-Delphi study, researchers should carefully consider the design and methods for collecting data, to avoid challenges that could potentially compromise the quality of the findings. Researchers are encouraged to publish details about their approaches to e-Delphi studies, to advance the state of the science.

  14. Challenges of Conducting Systematic Research in Australia's Northern Territory

    ERIC Educational Resources Information Center

    Helmer, Janet; Harper, Helen; Lea, Tess; Wolgemuth, Jennifer R.; Chalkiti, Kalotina

    2014-01-01

    This paper explores the challenges of conducting systematic research, using our experiences of conducting a study to evaluate the effectiveness of ABRACADABRA, an online tool for early childhood literacy instruction as the contextual framework. By discussing how the research team resolved such perennial issues as high teacher turnover, low or…

  15. Researcher Perceptions of Ethical Guidelines and Codes of Conduct

    PubMed Central

    Giorgini, Vincent; Mecca, Jensen T.; Gibson, Carter; Medeiros, Kelsey; Mumford, Michael D.; Connelly, Shane; Devenport, Lynn D.

    2014-01-01

    Ethical codes of conduct exist in almost every profession. Field-specific codes of conduct have been around for decades, each articulating specific ethical and professional guidelines. However, there has been little empirical research on researchers’ perceptions of these codes of conduct. In the present study, we interviewed faculty members in six research disciplines and identified five themes bearing on the circumstances under which they use ethical guidelines and the underlying reasons for not adhering to such guidelines. We then identify problems with the manner in which codes of conduct in academia are constructed and offer solutions for overcoming these problems. PMID:25635845

  16. Conducting a successful residency research project.

    PubMed

    Barletta, Jeffrey F

    2008-08-15

    The residency research project can be a challenging endeavor for pharmacy residents since they typically have limited experience in this area. Furthermore, as the number of accredited residency programs has increased, so has the demand for preceptors with research experience. This review is intended to assist the resident and preceptor by providing steps and guidance with conducting a successful residency research project. Items such as idea generation, proposing the right type of project, departmental review, and project management skills are discussed and guidance with writing the research protocol is provided. Items that must be addressed in every research protocol are described and a generalized protocol template is presented. In addition, the institutional review board review process is described and tips and pointers for obtaining approval are included. Finally, useful tools and resources are provided that can be used up front or throughout each phase of the research project.

  17. [Research activities in Kobe-Indonesia Collaborative Research Centers].

    PubMed

    Utsumi, Takako; Hayashi, Yoshitake; Hotta, Hak

    2013-01-01

    Kobe-Indonesia Collaborative Research Center was established in Institute of Tropical Disease (ITD), Airlangga University, Surabaya, Indonesia in 2007 under the program of ''Founding Research Centers for Emerging and Reemerging Infectious Diseases'' supported by the Ministry of Education, Culture, Sports, Science and Technology, Japan, and then it has been under the Japan Initiative for Global Research Network on Infectious Diseases (J-GRID) since 2010. Japanese researchers have been stationed at ITD, conducting joint researches on influenza, viral hepatitis, dengue and infectious diarrhea. Also, another Japanese researcher has been stationed at Faculty of Medicine, University of Indonesia, Jakarta, carrying out joint researches on'' Identification of anti-hepatitis C virus (HCV) substances and development of HCV and dengue vaccines'' in collaboration with University of Indonesia and Airlangga University through the Science and Technology Research Partnership for Sustainable Development (SATREPS) supported by the Japan Science and Technology Agency (JST) and Japan International Cooperation Agency (JICA) since 2009. In this article, we briefly introduce the background history of Kobe University Research Center in Indonesia, and discuss the research themes and outcomes of J-GRID and SATREPS activities.

  18. A human intermediate conductance calcium-activated potassium channel.

    PubMed

    Ishii, T M; Silvia, C; Hirschberg, B; Bond, C T; Adelman, J P; Maylie, J

    1997-10-14

    An intermediate conductance calcium-activated potassium channel, hIK1, was cloned from human pancreas. The predicted amino acid sequence is related to, but distinct from, the small conductance calcium-activated potassium channel subfamily, which is approximately 50% conserved. hIK1 mRNA was detected in peripheral tissues but not in brain. Expression of hIK1 in Xenopus oocytes gave rise to inwardly rectifying potassium currents, which were activated by submicromolar concentrations of intracellular calcium (K0.5 = 0.3 microM). Although the K0.5 for calcium was similar to that of small conductance calcium-activated potassium channels, the slope factor derived from the Hill equation was significantly reduced (1.7 vs. 3. 5). Single-channel current amplitudes reflected the macroscopic inward rectification and revealed a conductance level of 39 pS in the inward direction. hIK1 currents were reversibly blocked by charybdotoxin (Ki = 2.5 nM) and clotrimazole (Ki = 24.8 nM) but were minimally affected by apamin (100 nM), iberiotoxin (50 nM), or ketoconazole (10 microM). These biophysical and pharmacological properties are consistent with native intermediate conductance calcium-activated potassium channels, including the erythrocyte Gardos channel.

  19. Conducting Research: A Handbook for School Social Workers.

    ERIC Educational Resources Information Center

    McCullagh, James G., Ed.; Allen-Meares, Paula, Ed.

    This handbook on conducting research was written for school social workers and contains these articles: (1) "The School Social Work Practitioner and Research: An Overview" (Elizabeth Timberlake and Lewis Carr); (2) "Defining Empirically Based Practice" (Deborah Siegel); (3) "Future Research in School Social Work Services: An Update" (Christine…

  20. 30 CFR 250.207 - What ancillary activities may I conduct?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What ancillary activities may I conduct? 250... and Information Ancillary Activities § 250.207 What ancillary activities may I conduct? Before or... the Regional Supervisor may direct you to conduct ancillary activities. Ancillary activities include...

  1. Challenges in Conducting Qualitative Research with Persons with Dementia

    PubMed Central

    Beuscher, Linda; Grando, Victoria T.

    2010-01-01

    Qualitative research can capture the meaningful experiences and life values of persons with dementia not reported in quantitative studies. This researcher shares personal experience of the challenges faced and the lessons learned while conducting a qualitative study of 15 persons with early stage Alzheimer’s disease. The purpose of this paper is to discuss the issues concerning determination of capacity to consent to research, consent/assent, communication challenges, and trustworthiness of data when conducting a qualitative study of persons with dementia. Understanding communication challenges due to dementia is important to develop effective communication strategies, such as simplifying the structure of questions, allowing ample time for participant’s response, using reminiscence, and redirecting the dialogue. This information will be valuable to researchers conducting future qualitative studies and the resulting contributions to the body of knowledge about Alzheimer’s PMID:20077988

  2. How To Conduct Collaborative Action Research.

    ERIC Educational Resources Information Center

    Sagor, Richard

    Collaborative action research, conducted by teams of practitioners, is a process that enables teachers: (1) to improve student learning, (2) to improve their own practice, (3) to contribute to the development of their own profession, and (4) to overcome the isolation commonly experienced by classroom teachers. By promoting collegial relationships…

  3. 30 CFR 250.207 - What ancillary activities may I conduct?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What ancillary activities may I conduct? 250... Activities § 250.207 What ancillary activities may I conduct? Before or after you submit an EP, DPP, or DOCD... direct you to conduct ancillary activities. Ancillary activities include: (a) Geological and geophysical...

  4. A human intermediate conductance calcium-activated potassium channel

    PubMed Central

    Ishii, Takahiro M.; Silvia, Christopher; Hirschberg, Birgit; Bond, Chris T.; Adelman, John P.; Maylie, James

    1997-01-01

    An intermediate conductance calcium-activated potassium channel, hIK1, was cloned from human pancreas. The predicted amino acid sequence is related to, but distinct from, the small conductance calcium-activated potassium channel subfamily, which is ≈50% conserved. hIK1 mRNA was detected in peripheral tissues but not in brain. Expression of hIK1 in Xenopus oocytes gave rise to inwardly rectifying potassium currents, which were activated by submicromolar concentrations of intracellular calcium (K0.5 = 0.3 μM). Although the K0.5 for calcium was similar to that of small conductance calcium-activated potassium channels, the slope factor derived from the Hill equation was significantly reduced (1.7 vs. 3.5). Single-channel current amplitudes reflected the macroscopic inward rectification and revealed a conductance level of 39 pS in the inward direction. hIK1 currents were reversibly blocked by charybdotoxin (Ki = 2.5 nM) and clotrimazole (Ki = 24.8 nM) but were minimally affected by apamin (100 nM), iberiotoxin (50 nM), or ketoconazole (10 μM). These biophysical and pharmacological properties are consistent with native intermediate conductance calcium-activated potassium channels, including the erythrocyte Gardos channel. PMID:9326665

  5. Conducting collaborative abortion research in international settings.

    PubMed

    Gipson, Jessica D; Becker, Davida; Mishtal, Joanna Z; Norris, Alison H

    2011-01-01

    Nearly 20% of the 208 million pregnancies that occur annually are aborted. More than half of these (21.6 million) are unsafe, resulting in 47,000 abortion-related deaths each year. Accurate reports on the prevalence of abortion, the conditions under which it occurs, and the experiences women have in obtaining abortions are essential to addressing unsafe abortion globally. It is difficult, however, to obtain accurate and reliable reports of attitudes and practices given that abortion is often controversial and stigmatized, even in settings where it is legal. To improve the understanding and measurement of abortion, specific considerations are needed throughout all stages of the planning, design, and implementation of research on abortion: Establishment of strong local partnerships, knowledge of local culture, integration of innovative methodologies, and approaches that may facilitate better reporting. This paper draws on the authors' collaborative research experiences conducting abortion-related studies using clinic- and community-based samples in five diverse settings (Poland, Zanzibar, Mexico City, the Philippines, and Bangladesh). The purpose of this paper is to share insights and lessons learned with new and established researchers to inform the development and implementation of abortion-related research. The paper discusses the unique challenges of conducting abortion-related research and key considerations for the design and implementation of abortion research, both to maximize data quality and to frame inferences from this research appropriately. Copyright © 2011 Jacobs Institute of Women's Health. Published by Elsevier Inc. All rights reserved.

  6. Getting started in research: designing and preparing to conduct a research study.

    PubMed

    Macfarlane, Matthew D; Kisely, Steve; Loi, Samantha; Macfarlane, Stephen; Merry, Sally; Parker, Stephen; Power, Brian; Siskind, Dan; Smith, Geoff; Looi, Jeffrey C

    2015-02-01

    To discuss common pitfalls and useful tips in designing a quantitative research study, the importance and process of ethical approval, and consideration of funding. Through careful planning, based on formulation of a research question, early career researchers can design and conduct quantitative research projects within the framework of the Scholarly Project or in their own independent projects. © The Royal Australian and New Zealand College of Psychiatrists 2014.

  7. Conducting Quantitative Medical Education Research: From Design to Dissemination.

    PubMed

    Abramson, Erika L; Paul, Caroline R; Petershack, Jean; Serwint, Janet; Fischel, Janet E; Rocha, Mary; Treitz, Meghan; McPhillips, Heather; Lockspeiser, Tai; Hicks, Patricia; Tewksbury, Linda; Vasquez, Margarita; Tancredi, Daniel J; Li, Su-Ting T

    2018-03-01

    Rigorous medical education research is critical to effectively develop and evaluate the training we provide our learners. Yet many clinical medical educators lack the training and skills needed to conduct high-quality medical education research. We offer guidance on conducting sound quantitative medical education research. Our aim is to equip readers with the key skills and strategies necessary to conduct successful research projects, highlighting new concepts and controversies in the field. We utilize Glassick's criteria for scholarship as a framework to discuss strategies to ensure that the research question of interest is worthy of further study and how to use existing literature and conceptual frameworks to strengthen a research study. Through discussions of the strengths and limitations of commonly used study designs, we expose the reader to particular nuances of these decisions in medical education research and discuss outcomes generally focused on, as well as strategies for determining the significance of consequent findings. We conclude with information on critiquing research findings and preparing results for dissemination to a broad audience. Practical planning worksheets and comprehensive tables illustrating key concepts are provided in order to guide researchers through each step of the process. Medical education research provides wonderful opportunities to improve how we teach our learners, to satisfy our own intellectual curiosity, and ultimately to enhance the care provided to patients. Copyright © 2018 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

  8. Pre-Service Science Teachers' Understandings of Classroom Research and the Problems in Conducting Classroom Research Projects

    ERIC Educational Resources Information Center

    Jantarakantee, Ekgapoom; Roadrangka, Vantipa; Clarke, Anthony

    2012-01-01

    This research paper explores pre-service science teachers' understandings of classroom research, problems in conducting classroom research and the supports that pre-service science teachers need from their cooperating teachers to help them conduct a classroom research project during the internship period. The participants in this study are 19…

  9. Conducting Intervention Research among Underserved Populations: Lessons Learned and Recommendations for Researchers

    PubMed Central

    Pyatak, Elizabeth A.; Blanche, Erna I.; Garber, Susan L.; Diaz, Jesus; Blanchard, Jeanine; Florindez, Lucia; Clark, Florence A.

    2013-01-01

    Randomized controlled trials (RCTs) are considered the gold standard in research design for establishing treatment efficacy. However, the rigorous and highly controlled conditions of RCTs can be difficult to attain when conducting research among individuals living with a confluence of disability, low socioeconomic status, and being a member of a racial/ethnic minority group, who may be more likely to have unstable life circumstances. Research on effective interventions for these groups is urgently needed, as evidence regarding approaches to reduce health disparities and improve health outcomes is lacking. In this methodological paper we discuss the challenges and lessons learned in implementing the Lifestyle Redesign® for Pressure Ulcer Prevention in Spinal Cord Injury (LR-PUPS) study among a highly disadvantaged population. These issues are discussed in terms of strategies to enhance recruitment, retention, and intervention relevance to the target population. Recommendations for researchers seeking to conduct RCTs among socioeconomically disadvantaged, ethnically diverse populations are provided. PMID:23262157

  10. Research Review: DSM-V Conduct Disorder--Research Needs for an Evidence Base

    ERIC Educational Resources Information Center

    Moffitt, Terrie E.; Arseneault, Louise; Jaffee, Sara R.; Kim-Cohen, Julia; Koenen, Karestan C.; Odgers, Candice L.; Slutske, Wendy S.; Viding, Essi

    2008-01-01

    This article charts a strategic research course toward an empirical foundation for the diagnosis of conduct disorder in the forthcoming DSM-V. Since the DSM-IV appeared in 1994, an impressive amount of new information about conduct disorder has emerged. As a result of this new knowledge, reasonable rationales have been put forward for adding to…

  11. Conducting Nursing Research to Advance and Inform Health Policy.

    PubMed

    Ellenbecker, Carol Hall; Edward, Jean

    2016-11-01

    The primary roles of nurse scientists in conducting health policy research are to increase knowledge in the discipline and provide evidence for informing and advancing health policies with the goal of improving the health outcomes of society. Health policy research informs, characterizes, explains, or tests hypotheses by employing a variety of research designs. Health policy research focuses on improving the access to care, the quality and cost of care, and the efficiency with which care is delivered. In this article, we explain how nurses might envision their research in a policy process framework, describe research designs that nurse researchers might use to inform and advance health policies, and provide examples of research conducted by nurse researchers to explicate key concepts in the policy process framework. Health policies are well informed and advanced when nurse researchers have a good understanding of the political process. The policy process framework provides a context for improving the focus and design of research and better explicating the connection between research evidence and policy. Nurses should focus their research on addressing problems of importance that are on the healthcare agenda, work with interdisciplinary teams of researchers, synthesize, and widely disseminate results.

  12. Attitudes on Conducting Thesis Research in a Developing Country.

    ERIC Educational Resources Information Center

    Mason, S. C.; And Others

    1987-01-01

    Reports on a survey conducted to study attitudes toward agronomy graduate students conducting thesis research in developing countries. Compares perceptions of executive officers of international program offices and departments of agronomy, and major professors. (TW)

  13. Community Researchers Conducting Health Disparities Research: Ethical and other insights from fieldwork journaling

    PubMed Central

    Mosavel, Maghboeba; Ahmed, Rashid; Daniels, Doria; Simon, Christian

    2011-01-01

    Lay persons who are trained to conduct research in their own communities form an essential part of many research projects. However, the effects of conducting research in their own communities have not been adequately explored. This paper examines the experiences, perceptions, and challenges faced by a group of community researchers during their involvement in a research project that examined if, and how, the relationships between mothers and their adolescent daughters could be harnessed to develop a daughter-initiated cervical cancer intervention. Seven community researchers interviewed 157 mother-daughter pairs in Cape Town, South Africa. We examine the use of journaling as a tool to document the experiences of community researchers, and we consider how journaling may help the community-based researcher grapple with the research process, and, more broadly, what such journal content illustrates with respect to the nature and challenges of community-engaged health research. An analysis of the content of the journals provides a strong indication of how personal and intimate the research process can be for community researchers by virtue of the background that they bring into the process as well as the additional weight of the research process itself. The complexities of navigating dual and somewhat oppositional roles – the role of impartial scientist or researcher and the role of invested community person - has been both underestimated and insufficiently researched. PMID:21680071

  14. Ethical conduct for research : a code of scientific ethics

    Treesearch

    Marcia Patton-Mallory; Kathleen Franzreb; Charles Carll; Richard Cline

    2000-01-01

    The USDA Forest Service recently developed and adopted a code of ethical conduct for scientific research and development. The code addresses issues related to research misconduct, such as fabrication, falsification, or plagiarism in proposing, performing, or reviewing research or in reporting research results, as well as issues related to professional misconduct, such...

  15. Guidance for Researchers Developing and Conducting Clinical Trials in Practice-based Research Networks (PBRNs)

    PubMed Central

    Dolor, Rowena J.; Schmit, Kristine M.; Graham, Deborah G.; Fox, Chester H.; Baldwin, Laura Mae

    2015-01-01

    Background There is increased interest nationally in multicenter clinical trials to answer questions about clinical effectiveness, comparative effectiveness, and safety in real-world community settings. Primary care practice-based research networks (PBRNs), comprising community- and/or academically affiliated practices committed to improving medical care for a range of health problems, offer ideal settings for these trials, especially pragmatic clinical trials. However, many researchers are not familiar with working with PBRNs. Methods Experts in practice-based research identified solutions to challenges that researchers and PBRN personnel experience when collaborating on clinical trials in PBRNs. These were organized as frequently asked questions in a draft document presented at a 2013 Agency for Health care Research and Quality PBRN conference workshop, revised based on participant feedback, then shared with additional experts from the DARTNet Institute, Clinical Translational Science Award PBRN, and North American Primary Care Research Group PBRN workgroups for further input and modification. Results The “Toolkit for Developing and Conducting Multi-site Clinical Trials in Practice-Based Research Networks” offers guidance in the areas of recruiting and engaging practices, budgeting, project management, and communication, as well as templates and examples of tools important in developing and conducting clinical trials. Conclusion Ensuring the successful development and conduct of clinical trials in PBRNs requires a highly collaborative approach between academic research and PBRN teams. PMID:25381071

  16. Conducting Precision Medicine Research with African Americans.

    PubMed

    Halbert, Chanita Hughes; McDonald, Jasmine; Vadaparampil, Susan; Rice, LaShanta; Jefferson, Melanie

    2016-01-01

    Precision medicine is an approach to detecting, treating, and managing disease that is based on individual variation in genetic, environmental, and lifestyle factors. Precision medicine is expected to reduce health disparities, but this will be possible only if studies have adequate representation of racial minorities. It is critical to anticipate the rates at which individuals from diverse populations are likely to participate in precision medicine studies as research initiatives are being developed. We evaluated the likelihood of participating in a clinical study for precision medicine. Observational study conducted between October 2010 and February 2011 in a national sample of African Americans. Intentions to participate in a government sponsored study that involves providing a biospecimen and generates data that could be shared with other researchers to conduct future studies. One third of respondents would participate in a clinical study for precision medicine. Only gender had a significant independent association with participation intentions. Men had a 1.86 (95% CI = 1.11, 3.12, p = 0.02) increased likelihood of participating in a precision medicine study compared to women in the model that included overall barriers and facilitators. In the model with specific participation barriers, distrust was associated with a reduced likelihood of participating in the research described in the vignette (OR = 0.57, 95% CI = 0.34, 0.96, p = 0.04). African Americans may have low enrollment in PMI research. As PMI research is implemented, extensive efforts will be needed to ensure adequate representation. Additional research is needed to identify optimal ways of ethically describing precision medicine studies to ensure sufficient recruitment of racial minorities.

  17. Conducting qualitative research within Clinical Trials Units: avoiding potential pitfalls.

    PubMed

    Cooper, Cindy; O'Cathain, Alicia; Hind, Danny; Adamson, Joy; Lawton, Julia; Baird, Wendy

    2014-07-01

    The value of using qualitative research within or alongside randomised controlled trials (RCTs) is becoming more widely accepted. Qualitative research may be conducted concurrently with pilot or full RCTs to understand the feasibility and acceptability of the interventions being tested, or to improve trial conduct. Clinical Trials Units (CTUs) in the United Kingdom (UK) manage large numbers of RCTs and, increasingly, manage the qualitative research or collaborate with qualitative researchers external to the CTU. CTUs are beginning to explicitly manage the process, for example, through the use of standard operating procedures for designing and implementing qualitative research with trials. We reviewed the experiences of two UK Clinical Research Collaboration (UKCRC) registered CTUs of conducting qualitative research concurrently with RCTs. Drawing on experiences gained from 15 studies, we identify the potential for the qualitative research to undermine the successful completion or scientific integrity of RCTs. We show that potential problems can arise from feedback of interim or final qualitative findings to members of the trial team or beyond, in particular reporting qualitative findings whilst the trial is on-going. The problems include: We make recommendations for improving the management of qualitative research within CTUs. Copyright © 2014. Published by Elsevier Inc.

  18. Active subthreshold dendritic conductances shape the local field potential

    PubMed Central

    Ness, Torbjørn V.; Remme, Michiel W. H.

    2016-01-01

    Key points The local field potential (LFP), the low‐frequency part of extracellular potentials recorded in neural tissue, is often used for probing neural circuit activity. Interpreting the LFP signal is difficult, however.While the cortical LFP is thought mainly to reflect synaptic inputs onto pyramidal neurons, little is known about the role of the various subthreshold active conductances in shaping the LFP.By means of biophysical modelling we obtain a comprehensive qualitative understanding of how the LFP generated by a single pyramidal neuron depends on the type and spatial distribution of active subthreshold currents.For pyramidal neurons, the h‐type channels probably play a key role and can cause a distinct resonance in the LFP power spectrum.Our results show that the LFP signal can give information about the active properties of neurons and imply that preferred frequencies in the LFP can result from those cellular properties instead of, for example, network dynamics. Abstract The main contribution to the local field potential (LFP) is thought to stem from synaptic input to neurons and the ensuing subthreshold dendritic processing. The role of active dendritic conductances in shaping the LFP has received little attention, even though such ion channels are known to affect the subthreshold neuron dynamics. Here we used a modelling approach to investigate the effects of subthreshold dendritic conductances on the LFP. Using a biophysically detailed, experimentally constrained model of a cortical pyramidal neuron, we identified conditions under which subthreshold active conductances are a major factor in shaping the LFP. We found that, in particular, the hyperpolarization‐activated inward current, I h, can have a sizable effect and cause a resonance in the LFP power spectral density. To get a general, qualitative understanding of how any subthreshold active dendritic conductance and its cellular distribution can affect the LFP, we next performed a systematic

  19. Considerations for planning and conducting clinic-based research in physical therapy.

    PubMed

    Fitzgerald, G K; Delitto, A

    2001-08-01

    There is growing demand to increase the volume of clinic-based research in physical therapy. Special considerations, unique to the planning and conduct of clinic-based research, need to be addressed to increase the likelihood that these studies will be completed successfully. The purposes of this perspective are to discuss factors affecting clinic-based research and to offer suggestions for addressing these problems when designing and conducting research studies in a clinical setting. This perspective discusses issues such as patient management, determining the availability of target patient populations, acquiring support from physical therapists and physicians, reporting and managing research-related injury or illness, and modifying or terminating projects. Some of the points made in this perspective are illustrated using examples from the authors' experiences in conducting clinical research.

  20. Conducting Clinical Research Using Crowdsourced Convenience Samples.

    PubMed

    Chandler, Jesse; Shapiro, Danielle

    2016-01-01

    Crowdsourcing has had a dramatic impact on the speed and scale at which scientific research can be conducted. Clinical scientists have particularly benefited from readily available research study participants and streamlined recruiting and payment systems afforded by Amazon Mechanical Turk (MTurk), a popular labor market for crowdsourcing workers. MTurk has been used in this capacity for more than five years. The popularity and novelty of the platform have spurred numerous methodological investigations, making it the most studied nonprobability sample available to researchers. This article summarizes what is known about MTurk sample composition and data quality with an emphasis on findings relevant to clinical psychological research. It then addresses methodological issues with using MTurk--many of which are common to other nonprobability samples but unfamiliar to clinical science researchers--and suggests concrete steps to avoid these issues or minimize their impact.

  1. Recent researches concerning the obtaining of functional textiles based on conductive yarns

    NASA Astrophysics Data System (ADS)

    Leon, A. L.; Manea, L. R.; Hristian, L.

    2016-08-01

    Modem textile industry is influenced both by consumers' lifestyle and by novel materials. Functional textiles can be included into the group of technical textiles. The functional activity can be shortly interpreted as "sense - react - adapt" to the environment while traditional materials meet only passive protective role, a barrier between body and environment. Functional materials cross the conventional limits because they are designed for specific performances, being part of domains as: telemedicine, medicine, aeronautics, biotechnology, nanotechnology, protective clothes, sportswear, etc. This paper highlights the most recent developments in the field of using conductive yarns for obtaining functional textiles. Conductive fabrics can be done by incorporating into the textile structure the conductive fibers / yarns. The technologies differ from embroidering, sewing, weaving, knitting to braiding and obtaining nonwovens. The conductive fabrics production has a quickly growth because it is a high demand for these textiles used for data transfer in clothing, monitoring vital signs, germ-free garments, brain-computer interface, etc. Nowadays it is of high interest surface treatments of fibers/yarns which can be considered as a novel kind of textile finishing. There are presented some researches related to obtaining conductive yarns by coating PET and PP yarns with PANi conductive polymer.

  2. Conducting phenomenological research: Rationalizing the methods and rigour of the phenomenology of practice.

    PubMed

    Errasti-Ibarrondo, Begoña; Jordán, José Antonio; Díez-Del-Corral, Mercedes P; Arantzamendi, María

    2018-07-01

    To offer a complete outlook in a readable easy way of van Manen's hermeneutic-phenomenological method to nurses interested in undertaking phenomenological research. Phenomenology, as research methodology, involves a certain degree of complexity. It is difficult to identify a single article or author which sets out the didactic guidelines that specifically guide research of this kind. In this context, the theoretical-practical view of Max van Manen's Phenomenology of Practice may be seen as a rigorous guide and directive on which researchers may find support to undertake phenomenological research. Discussion paper. This discussion paper is based on our own experiences and supported by literature and theory. Our central sources of data have been the books and writings of Max van Manen and his website "Phenomenologyonline". The principal methods of the hermeneutic-phenomenological method are addressed and explained providing an enriching overview of phenomenology of practice. A proposal is made for the way the suggestions made by van Manen might be organized for use with the methods involved in Phenomenology of Practice: Social sciences, philosophical and philological methods. Thereby, nurse researchers interested in conducting phenomenological research may find a global outlook and support to understand and conduct this type of inquiry which draws on the art. The approach in this article may help nurse scholars and researchers reach an overall, encompassing perspective of the main methods and activities involved in doing phenomenological research. Nurses interested in doing phenomenology of practice are expected to commit with reflection and writing. © 2018 John Wiley & Sons Ltd.

  3. Logistical Challenges and Opportunities for Conducting Peer Nomination Research in Schools.

    PubMed

    Mayeux, Lara; Kraft, Caroline

    2017-09-01

    Although conducting psychological research within schools has always required effort, persistence, and the careful navigation of various interests, there is a consensus among child and adolescent researchers that, over the past 2 decades, it has become increasingly difficult to collect data within schools. In this chapter, we lay out common and consistent difficulties, frustrations, and obstacles that researchers face when attempting to conduct peer nomination research in schools. Many of these difficulties are faced not only by researchers conducting peer nominations but by any investigator attempting to do school-based research, and we discuss these issues more broadly. We also focus on the specific challenges associated with sociometric methods. We present suggestions and solutions for overcoming these issues and consider ways that researchers can give back to schools and establish long-term partnerships that benefit the students, teachers, and administrators of participating schools, as well as the researchers themselves. Such partnerships have the potential to make data collection easier and to open doors to new research opportunities. © 2017 Wiley Periodicals, Inc.

  4. Nature and governance of veterinary clinical research conducted in the UK.

    PubMed

    Fordyce, P; Mullan, S

    2017-01-21

    In order to quantify the amount of clinical research conducted on client-owned animals under the Veterinary Surgeons Act 1966, and the nature and extent of any ethical review of that research, a questionnaire was sent to 6 UK veterinary schools, 1 charity veterinary clinic and 12 private referral clinics. The questionnaire examined whether and how much clinical research respondents undertook, and the composition of any ethical review panels examining research proposals. The questionnaire revealed a substantial amount of clinical research was conducted in the UK, with over 200 veterinary surgeons involved in the year of the survey, with at least 170 academic papers involving clinical research published by respondents in the same year. However, it proved impossible to quantify the full extent of clinical research in the UK. All UK veterinary schools required ethical review of clinical research. The composition and working practices of their ethical review panels generally reflected skill sets in ethical review panels set-up under statute to consider the ethics of non-clinical biomedical research on animals and clinical research conducted on human patients. The process for review of clinical research in the private sector was less clear. British Veterinary Association.

  5. [Research activities of cosmonauts in long-duration orbital missions].

    PubMed

    2012-01-01

    The paper presents the view of space medicine and human factor experts on the problems of cosmonaut's research activities. Readiness of ISS crewmembers for conducting experiments and research equipment handling depends on the pre-flight training quality and course of adaptation to the flight conditions, the latter of particular criticality for participation in human use tests as an object.

  6. Conducting research and collaborating with researchers: the experience of clinicians in a residential treatment center.

    PubMed

    Adelman, Robert W; Castonguay, Louis G; Kraus, David R; Zack, Sanno E

    2015-01-01

    This paper describes the experience of clinicians in conducting research and collaborating with academic researchers. As part of clinical routine of a residential program for adolescent substance abusers, empirical data have been collected to assess client's needs before and after treatment, improve clinical practice, and identify barriers to change. Some of the challenges faced and the benefits learned in conducting these studies are presented. In addition to highlighting the convergence of research interests between clinicians and academicians, the conclusion offers general recommendations to foster these partnerships and solidify the scientific-practitioner model.

  7. Research as Profession and Practice: Frameworks for Guiding the Responsible Conduct of Research.

    PubMed

    Chen, Jiin-Yu

    2016-01-01

    Programs in the responsible conduct of research (RCR) vary between institutions, demonstrated by disparate structures and goals. These variations may be attributed to the absence of grounding frameworks within which to examine research and RCR education programs. This article examines research as a practice and a profession, using these frames to draw out defining features of research and the moral obligations entailed. Situating research within virtue ethics can clarify how researchers might cultivate the virtues necessary for meeting its obligations and aims. By elucidating these features, these perspectives can serve to guide the development of RCR education programs.

  8. Ethical Issues Involving Research Conducted with Homebound Older Adults

    ERIC Educational Resources Information Center

    Locher, Julie L.; Bronstein, Janet; Robinson, Caroline O.; Williams, Charlotte; Ritchie, Christine S.

    2006-01-01

    Conducting research in the home setting with homebound older adults presents distinct ethical and practical challenges that require special consideration. This article describes the methodological issues that make studying homebound older adults especially vulnerable to therapeutic misconception and researcher role conflict and offers practical…

  9. The Impact of the Physical Activity Policy Research Network.

    PubMed

    Manteiga, Alicia M; Eyler, Amy A; Valko, Cheryl; Brownson, Ross C; Evenson, Kelly R; Schmid, Thomas

    2017-03-01

    Lack of physical activity is one of the greatest challenges of the 21st century. The Physical Activity Policy Research Network (PAPRN) is a thematic network established in 2004 to identify determinants, implementation, and outcomes of policies that are effective in increasing physical activity. The purpose of this study is to describe the products of PAPRN and make recommendations for future research and best practices. A mixed methods approach was used to obtain both quantitative and qualitative data on the network. First, in 2014, PAPRN's dissemination products from 2004 to 2014 were extracted and reviewed, including 57 publications and 56 presentations. Next, semi-structured qualitative interviews were conducted with 25 key network participants from 17 locations around the U.S. The transcripts were transcribed and coded. The results of the interviews indicated that the research network addressed several components of its mission, including the identification of physical activity policies, determinants of these policies, and the process of policy implementation. However, research focusing on physical activity policy outcomes was limited. Best practices included collaboration between researchers and practitioners and involvement of practitioners in research design, data collection, and dissemination of results. PAPRN is an example of a productive research network and has contributed to both the process and content of physical activity policy research over the past decade. Future research should emphasize physical activity policy outcomes. Additionally, increased partnerships with practitioners for collaborative, cross-sectoral physical activity policy research should be developed. Copyright © 2016 American Journal of Preventive Medicine. All rights reserved.

  10. Regulatory Framework for Conducting Clinical Research in Canada.

    PubMed

    Alas, Josmar K; Godlovitch, Glenys; Mohan, Connie M; Jelinski, Shelly A; Khan, Aneal A

    2017-09-01

    Research in human subjects is at the core of achieving improvements in health outcomes. For clinical trials, in addition to the peer review of the results before publication, it is equally important to consider whether the trial will be conducted in a manner that generates data of the highest quality and provides a measure of safety for the participating subjects. In Canada, there is no definitive legislation that governs the conduct of research involving human subjects, but a network of regulations at different levels does provide a framework for both principal investigators and sponsors. In this paper, we provide an overview of the federal, provincial and institutional legislation, guidelines and policies that will inform readers about the requirements for clinical trial research. This includes a review of the role of the Food and Drug Regulations under the Food and Drugs Act and the Tri-Council Policy Statement (TCPS2), an overview of provincial legislation across the country, and a focus on selected policies from institutional research ethics boards and public health agencies. Many researchers may find navigation through regulations frustrating, and there is a paucity of information that explains the interrelationship between the different regulatory agencies in Canada. Better understanding the process, we feel, will facilitate investigators interested in clinical trials and also enhance the long-term health of Canadians.

  11. Perceptions of the Usefulness and Use of Research Conducted in Other Countries

    ERIC Educational Resources Information Center

    Burchett, Helen; Lavis, John N.; Mayhew, Susannah H.; Dobrow, Mark J.

    2012-01-01

    Semi-structured interviews in Ghana and England explored perceptions of the usefulness and use of foreign research (ie, beyond the original study country) compared to locally conducted research (ie, conducted in Ghana). There was a preference for locally conducted studies, although interviewees generally recognised the potential usefulness of…

  12. Behind Bars: Experiences Conducting Behavioral Addictions Research in a County Jail.

    PubMed

    Hickey, Kari L; Kerber, Cindy; Astroth, Kim Schafer; Kim, MyoungJin; Schlenker, Emily

    2015-10-01

    Individuals who are incarcerated experience disparities in mental health, warranting study by nurse researchers. However, nurse researchers' unfamiliarity with the jail environment may pose a barrier to conducting research with this vulnerable population. The current article presents an account of the planning and implementation needed to study perceived health and gambling behavior in county jail inmates. The challenges and rewards of research that aim to better understand the mental health issues affecting this population are also identified. Developing relationships with jail personnel and understanding the incarcerated population and their surroundings are key to conducting research in this environment. Copyright 2015, SLACK Incorporated.

  13. Challenges in conducting qualitative research in health: A conceptual paper.

    PubMed

    Khankeh, Hamidreza; Ranjbar, Maryam; Khorasani-Zavareh, Davoud; Zargham-Boroujeni, Ali; Johansson, Eva

    2015-01-01

    Qualitative research focuses on social world and provides the tools to study health phenomena from the perspective of those experiencing them. Identifying the problem, forming the question, and selecting an appropriate methodology and design are some of the initial challenges that researchers encounter in the early stages of any research project. These problems are particularly common for novices. This article describes the practical challenges of using qualitative inquiry in the field of health and the challenges of performing an interpretive research based on professional experience as a qualitative researcher and on available literature. One of the main topics discussed is the nature of qualitative research, its inherent challenges, and how to overcome them. Some of those highlighted here include: identification of the research problem, formation of the research question/aim, and selecting an appropriate methodology and research design, which are the main concerns of qualitative researchers and need to be handled properly. Insights from real-life experiences in conducting qualitative research in health reveal these issues. The paper provides personal comments on the experiences of a researcher in conducting pure qualitative research in the field of health. It offers insights into the practical difficulties encountered when performing qualitative studies and offers solutions and alternatives applied by these authors, which may be of use to others.

  14. A Context-Aware Ubiquitous Learning Approach to Conducting Scientific Inquiry Activities in a Science Park

    ERIC Educational Resources Information Center

    Hwang, Gwo-Jen; Tsai, Chin-Chung; Chu, Hui-Chun; Kinshuk; Chen, Chieh-Yuan

    2012-01-01

    Fostering students' scientific inquiry competence has been recognised as being an important and challenging objective of science education. To strengthen the understanding of science theories or notations, researchers have suggested conducting some learning activities in the field via operating relevant devices. In a traditional infield scientific…

  15. Research engagement of health sciences librarians: a survey of research-related activities and attitudes.

    PubMed

    Lessick, Susan; Perryman, Carol; Billman, Brooke L; Alpi, Kristine M; De Groote, Sandra L; Babin, Ted D

    2016-04-01

    The extent to which health sciences librarians are engaged in research is a little-studied question. This study assesses the research activities and attitudes of Medical Library Association (MLA) members, including the influence of work affiliation. An online survey was designed using a combination of multiple-choice and open-ended questions and distributed to MLA members. Responses were analyzed using descriptive statistics, content analysis, and significance testing. The authors used statistical tools and categorized open-ended question topics by the constant comparative method, also applying the broad subject categories used in a prior study. Pearson's chi-square analysis was performed on responses to determine significant differences among respondents employed in three different institutional environments. Analysis showed that 79% of respondents read research articles at least once a month; 58% applied published research studies to practice; 44% had conducted research; 62% reported acting on research had enhanced their libraries; 38% had presented findings; and 34% had authored research articles. Hospital librarians were significantly less likely than academic librarians to have participated in research activities. Highly ranked research benefits, barriers, and competencies of health sciences librarians are described. Findings indicate that health sciences librarians are actively engaged in research activities. Practice implications for practitioners, publishers, and stakeholders are discussed. Results suggest that practitioners can use published research results and results from their own research to affect practice decisions and improve services. Future studies are needed to confirm and extend these findings, including the need for intervention studies to increase research and writing productivity.

  16. Research engagement of health sciences librarians: a survey of research-related activities and attitudes

    PubMed Central

    Lessick, Susan; Perryman, Carol; Billman, Brooke L.; Alpi, Kristine M.; De Groote, Sandra L.; Babin, Ted D.

    2016-01-01

    Introduction The extent to which health sciences librarians are engaged in research is a little-studied question. This study assesses the research activities and attitudes of Medical Library Association (MLA) members, including the influence of work affiliation. Methods An online survey was designed using a combination of multiple-choice and open-ended questions and distributed to MLA members. Responses were analyzed using descriptive statistics, content analysis, and significance testing. The authors used statistical tools and categorized open-ended question topics by the constant comparative method, also applying the broad subject categories used in a prior study. Pearson's chi-square analysis was performed on responses to determine significant differences among respondents employed in three different institutional environments. Results Analysis showed that 79% of respondents read research articles at least once a month; 58% applied published research studies to practice; 44% had conducted research; 62% reported acting on research had enhanced their libraries; 38% had presented findings; and 34% had authored research articles. Hospital librarians were significantly less likely than academic librarians to have participated in research activities. Highly ranked research benefits, barriers, and competencies of health sciences librarians are described. Conclusions Findings indicate that health sciences librarians are actively engaged in research activities. Practice implications for practitioners, publishers, and stakeholders are discussed. Results suggest that practitioners can use published research results and results from their own research to affect practice decisions and improve services. Future studies are needed to confirm and extend these findings, including the need for intervention studies to increase research and writing productivity. PMID:27076808

  17. Challenges Confronting Beginning Researchers in Conducting Literature Reviews

    ERIC Educational Resources Information Center

    Chen, Der-Thanq; Wang, Yu-Mei; Lee, Wei Ching

    2016-01-01

    Conducting literature review is a complicated, sometimes confusing and laborious process that beginning educational researchers, especially graduate students, often find challenging. However, in the past these challenges were hardly considered, but in more recent times they have been increasingly considered by various faculties and graduate…

  18. Exploring the Challenges of Conducting Respectful Research: Seen and Unforeseen Factors within Urban School Research

    ERIC Educational Resources Information Center

    Samaroo, Julia; Dahya, Negin; Alidina, Shahnaaz

    2013-01-01

    This paper discusses the significance of conducting respectful research within urban schools, using the example of one large-scale university-school board partnership in northwestern Toronto. The authors, three research assistants on the project, use their experiences within three of the participating schools to interrogate the research approach…

  19. Towards the responsible conduct of scientific research: is ethics education enough?

    PubMed Central

    Novossiolova, Tatyana; Sture, Judi

    2012-01-01

    Much of the discourse on ‘beyond the laboratory door’ biosecurity to date has focused on the need to raise awareness among the scientific community of the risks posed by the rapid advancement of biotechnology in recent decades. While education is undoubtedly important, a growing body of evidence suggests that ethics education does not necessarily translate into ethical behaviour. This trend has already been reported in clinical settings, where research has highlighted doctors’ own reports of ethically dubious practices and challenges when confronted with moral dilemmas in their everyday work. The purpose of this paper is to critically evaluate the practical value of ethics education and show why it is an essential, although insufficient, measure for promoting a culture of responsible conduct of research. We conclude by highlighting the importance of continuing professional development as a way of maintaining life scientists’ engagement with biosecurity issues and supporting them in active roles in the effective implementation of the Biological and Toxin Weapons Convention (BWC). PMID:22606762

  20. 21 CFR 814.15 - Research conducted outside the United States.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Research conducted outside the United States. 814... SERVICES (CONTINUED) MEDICAL DEVICES PREMARKET APPROVAL OF MEDICAL DEVICES General § 814.15 Research... paragraph (b) or (c) of this section, as applicable. (b) Research begun on or after effective date. FDA will...

  1. Challenges in conducting qualitative research in health: A conceptual paper

    PubMed Central

    Khankeh, Hamidreza; Ranjbar, Maryam; Khorasani-Zavareh, Davoud; Zargham-Boroujeni, Ali; Johansson, Eva

    2015-01-01

    Background: Qualitative research focuses on social world and provides the tools to study health phenomena from the perspective of those experiencing them. Identifying the problem, forming the question, and selecting an appropriate methodology and design are some of the initial challenges that researchers encounter in the early stages of any research project. These problems are particularly common for novices. Materials and Methods: This article describes the practical challenges of using qualitative inquiry in the field of health and the challenges of performing an interpretive research based on professional experience as a qualitative researcher and on available literature. Results: One of the main topics discussed is the nature of qualitative research, its inherent challenges, and how to overcome them. Some of those highlighted here include: identification of the research problem, formation of the research question/aim, and selecting an appropriate methodology and research design, which are the main concerns of qualitative researchers and need to be handled properly. Insights from real-life experiences in conducting qualitative research in health reveal these issues. Conclusions: The paper provides personal comments on the experiences of a researcher in conducting pure qualitative research in the field of health. It offers insights into the practical difficulties encountered when performing qualitative studies and offers solutions and alternatives applied by these authors, which may be of use to others. PMID:26793245

  2. Acrylamide: update on selected research activities conducted by the European food and drink industry.

    PubMed

    Taeymans, Dominique; Andersson, Anders; Ashby, Peter; Blank, Imre; Gondé, Pierre; van Eijck, Paul; Faivre, Virginie; Lalljie, Sam P D; Lingnert, Hans; Lindblom, Marianne; Matissek, Reinhard; Müller, Detflef; Stadler, Richard H; Studer, Alfred; Silvani, David; Tallmadge, Dan; Thompson, Geoff; Whitmore, Tricia; Wood, John; Zyzak, David

    2005-01-01

    This paper reviews the progress made by the European food and drink industry (CIAA) on acrylamide with regard to analytical methods, mechanisms of formation, and mitigation research in the major food categories. It is an update on the first CIAA review paper, "A Review of Acrylamide: An Industry Perspective on Research, Analysis, Formation and Control." Initial difficulties with the establishment of reliable analytical methods, in most cases, have now been overcome, but challenges remain in terms of the need to develop simple and rapid test methods and certified reference materials. Many trials have been conducted under laboratory and experimental conditions in a variety of foods, and a number of possible measures have been identified to relatively lower the amounts of acrylamide in food. Promising applications were studied in reconstituted potato models by addition of amino acids or use of asparaginase. In bakery wares, predictive models have been established to determine the role of ammonium carbonate and invert sugar in acrylamide formation. Studies in several commercial foods showed that acrylamide is not stable over time in roasted and ground coffee. Some progress in relatively lowering acrylamide in certain food categories has been achieved, but at this stage can only be considered marginal. Any options that are chosen to reduce acrylamide in commercial products must be technologically feasible and must not adversely affect the quality and safety of the final product.

  3. A calcium-permeable cGMP-activated cation conductance in hippocampal neurons

    NASA Technical Reports Server (NTRS)

    Leinders-Zufall, T.; Rosenboom, H.; Barnstable, C. J.; Shepherd, G. M.; Zufall, F.

    1995-01-01

    Whole-cell patch clamp recordings detected a previously unidentified cGMP-activated membrane conductance in cultured rat hippocampal neurons. This conductance is nonselectively permeable for cations and is completely but reversibly blocked by external Cd2+. The Ca2+ permeability of the hippocampal cGMP-activated conductance was examined in detail, indicating that the underlying ion channels display a high relative permeability for Ca2+. The results indicate that hippocampal neurons contain a cGMP-activated membrane conductance that has some properties similar to the cyclic nucleotide-gated channels previously shown in sensory receptor cells and retinal neurons. In hippocampal neurons this conductance similarly could mediate membrane depolarization and Ca2+ fluxes in response to intracellular cGMP elevation.

  4. The Applied Behavior Analysis Research Paradigm and Single-Subject Designs in Adapted Physical Activity Research.

    PubMed

    Haegele, Justin A; Hodge, Samuel Russell

    2015-10-01

    There are basic philosophical and paradigmatic assumptions that guide scholarly research endeavors, including the methods used and the types of questions asked. Through this article, kinesiology faculty and students with interests in adapted physical activity are encouraged to understand the basic assumptions of applied behavior analysis (ABA) methodology for conducting, analyzing, and presenting research of high quality in this paradigm. The purposes of this viewpoint paper are to present information fundamental to understanding the assumptions undergirding research methodology in ABA, describe key aspects of single-subject research designs, and discuss common research designs and data-analysis strategies used in single-subject studies.

  5. The ethics of clinical research and the conduct of clinical drug trials: international comparisons and codes of conduct.

    PubMed

    Beran, R G

    2000-01-01

    Human research must respect most rigorous ethical standards to protect both the investigators and subjects. Codes of ethical practice relevant to such research are subjected to reviews around the world including The European Union (EU), the Canadian Tri-Council Policy Statement (including the Medical Research Council, the Natural Sciences and Engineering Research Council and the Social Sciences and Humanities Research Council), the Finnish Parliament Research Act (April 1999) and the National Statement on Ethical Conduct in Research Involving Humans in accordance with the NHMRC Act 1992 (Cth) from the National Health and Medical Research Council of Australia. The Australian Statement was endorsed by the Australian Vice-Chancellors' Committee, the Australian Research Council, the Australian Academy of the Humanities, the Australian Academy of Science and the Academy of Social Sciences in Australia and supported by the Academy of Technological Sciences and Engineering. This reflects the extensive ramifications of human experimentation and the range of stack holders. Private organisations have also produced interpretations of minimum standards of good clinical practice. The paper that follows analyses approaches to human experimentation and the minimal ethical expectations in the conduct of such research.

  6. Latino community-based participatory research studies: a model for conducting bilingual translations.

    PubMed

    Sánchez-Johnsen, Lisa; Escamilla, Julia; Rodriguez, Erin M; Vega, Susan; Bolaños, Liliana

    2015-01-01

    Many behavioral health materials have not been translated into Spanish. Of those that are available in Spanish, some of them have not been translated correctly, many are only appropriate for a subgroup of Latinos, and/or multiple versions of the same materials exist. This article describes an innovative model of conducting bilingual English-Spanish translations as part of community-based participatory research studies and provides recommendations based on this model. In this article, the traditional process of conducting bilingual translations is reviewed, and an innovative model for conducting translations in collaboration with community partners is described. Finally, recommendations for conducting future health research studies with community partners are provided. Researchers, health care providers, educators, and community partners will benefit from learning about this innovative model that helps produce materials that are more culturally appropriate than those that are produced with the most commonly used method of conducting translations.

  7. Building capacity for the conduct of nursing research at a Veterans Administration hospital.

    PubMed

    Phelan, Cynthia H; Schumacher, Sandra; Roiland, Rachel; Royer, Heather; Roberts, Tonya

    2015-05-01

    Evidence is the bedrock of nursing practice, and nursing research is the key source for this evidence. In this article, we draw distinctions between the use and the conduct of nursing research and provide a perspective for how the conduct of nursing research in a Veterans Administration hospital can build an organization's capacity for nursing research.

  8. Becoming a Scientist: Research Findings on STEM Students' Gains from Conducting Undergraduate Research

    NASA Astrophysics Data System (ADS)

    Hunter, A.; Laursen, S.; Thiry, H.; Seymour, E.

    2006-12-01

    Undergraduate research is widely believed to enhance STEM students' education and increase their persistence to graduate education and careers in the sciences. Yet until very recently, little evidence from research and evaluation studies was available to substantiate such claims and document what students gain from doing undergraduate research or how these gains come about. We have conducted a three-year qualitative research study of STEM students participating in UR at four liberal arts colleges with a strong tradition of faculty-led summer research apprenticeships. Benefits to students reported by both students and their faculty advisors are categorized into six main categories of gains in skills, knowledge, "thinking like a scientist," career preparation, career development, and personal and professional growth. Student and faculty observations are strongly corroborative, but also differ in interesting ways that reflect the distinct perspectives of each group: students are still in the midst of discovering their own career paths while faculty advisors have observed the later career development of their past research students. While not all students find UR to heighten their interest in graduate school, they do find it a powerful growth experience that clarifies their career ambitions by providing a "real world" experience of science. For students whose interest in science is reinforced, UR has a significant role in their professional socialization into the culture and norms of science, which we call "becoming a scientist," through interactions that draw them into the scientific community and experiences that deepen their understanding of the nature of research. Cumulatively, the qualitative data set of nearly 350 interviews offers a rich portrayal of the UR enterprise from a variety of perspectives. Longitudinal data enable us to track the influence of UR on students' career and education trajectories in the years after college, and comparative data from a group

  9. Health, human rights, and the conduct of clinical research within oppressed populations

    PubMed Central

    Mills, Edward J; Singh, Sonal

    2007-01-01

    Background Clinical trials evaluating interventions for infectious diseases require enrolling participants that are vulnerable to infection. As clinical trials are conducted in increasingly vulnerable populations, issues of protection of these populations become challenging. In settings where populations are forseeably oppressed, the conduct of research requires considerations that go beyond common ethical concerns and into issues of international human rights law. Discussion Using examples of HIV prevention trials in Thailand, hepatitis-E prevention trials in Nepal and malaria therapeutic trials in Burma (Myanmar), we address the inadequacies of current ethical guidelines when conducting research within oppressed populations. We review existing legislature in the United States and United Kingdom that may be used against foreign investigators if trial hardships exist. We conclude by making considerations for research conducted within oppressed populations. PMID:17996056

  10. Time Use Differences in Activity Participation among Children 4-5 Years Old with and without the Risk of Developing Conduct Problems

    ERIC Educational Resources Information Center

    Yu, Mong-Lin; Ziviani, Jenny; Baxter, Janeen; Haynes, Michele

    2012-01-01

    Conduct problems in childhood are associated with the way in which children engage in daily activities. Research, to date, on conduct problems in relation to time use has primarily focused on school aged children and their participation in discrete activities such as watching TV and sport. The purpose of the present study is to determine if…

  11. The HIV and Drug Abuse Prevention Research Ethics Training Institute: Training Early-Career Scientists to Conduct Research on Research Ethics

    PubMed Central

    Fisher, Celia B.; Yuko, Elizabeth

    2018-01-01

    The responsible conduct of HIV/drug abuse prevention research requires investigators with both the knowledge of and ability to generate empirical data that can enhance global ethical practices and policies. This article describes a multidisciplinary program offering early-career professionals a 2-year intensive summer curriculum along with funding to conduct a mentored research study on a wide variety of HIV/drug abuse research ethics topics. Now in its fifth year, the program has admitted 29 trainees who have to date demonstrated increased knowledge of research ethics, produced 17 peer-reviewed publications, 46 professional presentations, and submitted or been awarded five related federal grants. The institute also hosts a global information platform providing general and HIV/drug abuse relevant research ethics educational and research resources that have had more than 38,800 unique visitors from more than 150 countries. PMID:26564944

  12. Conducting multicenter research in healthcare simulation: Lessons learned from the INSPIRE network.

    PubMed

    Cheng, Adam; Kessler, David; Mackinnon, Ralph; Chang, Todd P; Nadkarni, Vinay M; Hunt, Elizabeth A; Duval-Arnould, Jordan; Lin, Yiqun; Pusic, Martin; Auerbach, Marc

    2017-01-01

    Simulation-based research has grown substantially over the past two decades; however, relatively few published simulation studies are multicenter in nature. Multicenter research confers many distinct advantages over single-center studies, including larger sample sizes for more generalizable findings, sharing resources amongst collaborative sites, and promoting networking. Well-executed multicenter studies are more likely to improve provider performance and/or have a positive impact on patient outcomes. In this manuscript, we offer a step-by-step guide to conducting multicenter, simulation-based research based upon our collective experience with the International Network for Simulation-based Pediatric Innovation, Research and Education (INSPIRE). Like multicenter clinical research, simulation-based multicenter research can be divided into four distinct phases. Each phase has specific differences when applied to simulation research: (1) Planning phase , to define the research question, systematically review the literature, identify outcome measures, and conduct pilot studies to ensure feasibility and estimate power; (2) Project Development phase , when the primary investigator identifies collaborators, develops the protocol and research operations manual, prepares grant applications, obtains ethical approval and executes subsite contracts, registers the study in a clinical trial registry, forms a manuscript oversight committee, and conducts feasibility testing and data validation at each site; (3) Study Execution phase , involving recruitment and enrollment of subjects, clear communication and decision-making, quality assurance measures and data abstraction, validation, and analysis; and (4) Dissemination phase , where the research team shares results via conference presentations, publications, traditional media, social media, and implements strategies for translating results to practice. With this manuscript, we provide a guide to conducting quantitative multicenter

  13. A Framework for Conducting Deceased Donor Research in the United States.

    PubMed

    Glazier, Alexandra K; Heffernan, Kate Gallin; Rodrigue, James R

    2015-11-01

    There are a number of regulatory barriers both perceived and real that have hampered widespread clinical research in the field of donation and transplantation. This article sets forth a framework clarifying the existing legal requirements and their application to the conduct of research on deceased donors and donor organs within the United States. Recommendations are focused on resolving some of the ambiguity surrounding deceased donor authorization for research, Health Insurance Portability and Accountability Act requirements and the role of institutional review board oversight. The successful conduct of clinical research in the field of donation and transplantation requires an understanding of these regulatory nuances as well as identification of important ethical principles to consider. Facilitation of these concepts will ultimately provide support for innovative research designed to increase the availability of organs for transplantation. Further work identifying the optimal infrastructure for overview of clinical research in the field should be given priority.

  14. Holistic Experiences and Strategies for Conducting Research With Couples.

    PubMed

    Braybrook, Debbie E; Mróz, Lawrence W; Robertson, Steve; White, Alan; Milnes, Kate

    2017-03-01

    In this article, we outline methodological considerations for conducting research interviews with couples. We draw from two qualitative men's health studies, both developed to explore social interactions between men and their partners of either sex in relation to their health practices. We utilized a combination of separate interviews and joint couple interviews. From these studies, we offer insight into our experiences of using both types of interview styles, addressing four key areas which span elements across the research project journey: (a) choosing a mode of interview, (b) ethical concerns in couple research, (c) the interview as a platform for disclosure, and (d) analyzing data from couple research.

  15. The HIV and Drug Abuse Prevention Research Ethics Training Institute: Training Early-Career Scientists to Conduct Research on Research Ethics.

    PubMed

    Fisher, Celia B; Yuko, Elizabeth

    2015-12-01

    The responsible conduct of HIV/drug abuse prevention research requires investigators with both the knowledge of and ability to generate empirical data that can enhance global ethical practices and policies. This article describes a multidisciplinary program offering early-career professionals a 2-year intensive summer curriculum along with funding to conduct a mentored research study on a wide variety of HIV/drug abuse research ethics topics. Now in its fifth year, the program has admitted 29 trainees who have to date demonstrated increased knowledge of research ethics, produced 17 peer-reviewed publications, 46 professional presentations, and submitted or been awarded five related federal grants. The institute also hosts a global information platform providing general and HIV/drug abuse relevant research ethics educational and research resources that have had more than 38,800 unique visitors from more than 150 countries. © The Author(s) 2015.

  16. Top 10 research questions related to children physical activity motivation.

    PubMed

    Chen, Ang

    2013-12-01

    Physical activity is critical to healthy development of children. It is well documented that helping children develop and sustain a physically active lifestyle requires children to become motivated. Many studies have been conducted in the past 2.5 decades on determinants and correlates for children and adolescents' physical activity motivation. The findings have informed researchers and practitioners about motivation sources for children and effective strategies to motivate children in given physical activity settings. Built on the extensive knowledge base and theoretical platforms formed by these research studies, the purpose of this article is to take a look at the current research landscape and provide subjective thoughts about what we still need to know about children's physical activity motivation. The product of this subjective thinking process rendered 10 potential questions for future research on children's physical activity motivation in both in-school and out-of-school settings. These topics encompass those focusing on children's physical activity motivation as a mental dispositional process, those conceptualizing the motivation as an outcome of person-environment interactions, and those attempting to dissect the motivation as an outcome of social-cultural influences and educational policies. It is hoped that the topics can serve researchers interested in children's physical activity motivation as starting blocks from which they can extend their conceptual thinking and identify research questions that are personally meaningful. It is also hoped that the list of potential questions can be helpful to researchers in accomplishing the imperative and significant mission to motivate children to be physically active in the 21st century and beyond.

  17. Practicalities and Research Considerations for Conducting Childhood Obesity Prevention Interventions with Families

    PubMed Central

    Morgan, Philip J.; Jones, Rachel A.; Collins, Clare E.; Hesketh, Kylie D.; Young, Myles D.; Burrows, Tracy L.; Magarey, Anthea M.; Brown, Helen L.; Hinkley, Trina; Perry, Rebecca A.; Brennan, Leah; Spence, Alison C.; Campbell, Karen J.

    2016-01-01

    Internationally, childhood obesity is a major public health concern. Given the established difficulties in treating obesity, designing and evaluating effective obesity prevention interventions are research priorities. As parents play a crucial role in establishing positive health behaviours in children, they are a key target for child obesity prevention programs. However, recruiting and engaging parents in such interventions can be a considerable challenge for researchers and practitioners. Members of the ‘Parenting, Child Behaviour and Well-being’ stream of the Australasian Child and Adolescent Obesity Research Network (ACAORN) have considerable and varied expertise in conducting such interventions and can provide insights into addressing these challenges. This paper aims to highlight considerations regarding the design, implementation, and evaluation of obesity prevention interventions with families and provide practical insights and recommendations for researchers and practitioners conducting family-based research in this area. Case studies of three family-based interventions conducted by ACAORN members are highlighted to provide examples and contextualise the recommendations proposed. PMID:27834820

  18. Conducting Research with the Disability Community: A Rights-Based Approach

    ERIC Educational Resources Information Center

    Munger, Kelly M.; Mertens, Donna M.

    2011-01-01

    This article explores philosophical and theoretical frameworks that are useful for the conduct of research with people with disabilities. It then uses these frameworks as a basis for discussion of research practices, with a specific focus on differences that occur because of specific impairments and various cultural meanings of disability. The…

  19. Challenges of Conducting Research With Young Offenders With Traumatic Brain Injury.

    PubMed

    OʼRourke, Conall; Templeton, Michelle; Cohen, Miriam H; Linden, Mark A

    2018-05-31

    The purpose of this commentary is to highlight the challenges encountered when conducting research with young offenders. This is drawn from the first-hand experience of 3 researchers working on separate projects within this environment. Young offenders present as a complex clinical population with high levels of illiteracy, substance abuse, and mental health issues. Significant planning is therefore required before working with this group. Consideration must be given to the heterogeneity of prison populations alongside the potential limitations of datacollection methods, in particular, reliance on self-report. The capacity of young offenders to comprehend and effectively engage with research is also of concern, posing issues of both a practical and ethical nature. The absence of a consistent "research culture" within prison environments poses further practical challenges, potentially also placing significant burden on both researchers and prison resources. The challenges discussed in this article may help inform future studies in the area and emphasize the need for greater critical reflection among researchers conducting work of this type.

  20. 75 FR 8677 - Takes of Marine Mammals Incidental to Specified Activities; Seabird and Pinniped Research...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... Marine Mammals Incidental to Specified Activities; Seabird and Pinniped Research Activities in Central... forth the permissible methods of taking, other means of effecting the least practicable adverse impact... the taking by harassment, of marine mammals incidental to conducting seabird and pinniped research...

  1. Device-based monitoring in physical activity and public health research.

    PubMed

    Bassett, David R

    2012-11-01

    Measurement of physical activity is important, given the vital role of this behavior in physical and mental health. Over the past quarter of a century, the use of small, non-invasive, wearable monitors to assess physical activity has become commonplace. This review is divided into three sections. In the first section, a brief history of physical activity monitoring is provided, along with a discussion of the strengths and weaknesses of different devices. In the second section, recent applications of physical activity monitoring in physical activity and public health research are discussed. Wearable monitors are being used to conduct surveillance, and to determine the extent and distribution of physical activity and sedentary behaviors in populations around the world. They have been used to help clarify the dose-response relation between physical activity and health. Wearable monitors that provide feedback to users have also been used in longitudinal interventions to motivate research participants and to assess their compliance with program goals. In the third section, future directions for research in physical activity monitoring are discussed. It is likely that new developments in wearable monitors will lead to greater accuracy and improved ease-of-use.

  2. Redox-active charge carriers of conducting polymers as a tuner of conductivity and its potential window

    PubMed Central

    Park, Han-Saem; Ko, Seo-Jin; Park, Jeong-Seok; Kim, Jin Young; Song, Hyun-Kon

    2013-01-01

    Electric conductivity of conducting polymers has been steadily enhanced towards a level worthy of being called its alias, “synthetic metal”. PEDOT:PSS (poly(3,4-ethylenedioxythiophene) doped with poly(styrene sulfonate)), as a representative conducting polymer, recently reached around 3,000 S cm−1, the value to open the possibility to replace transparent conductive oxides. The leading strategy to drive the conductivity increase is solvent annealing in which aqueous solution of PEDOT:PSS is treated with an assistant solvent such as DMSO (dimethyl sulfoxide). In addition to the conductivity enhancement, we found that the potential range in which PEDOT:PSS is conductive is tuned wider into a negative potential direction by the DMSO-annealing. Also, the increase in a redox-active fraction of charge carriers is proposed to be responsible for the enhancement of conductivity in the solvent annealing process. PMID:23949091

  3. Top 10 Research Questions Related to Children Physical Activity Motivation

    PubMed Central

    Chen, Ang

    2017-01-01

    Physical activity is critical to healthy development of children. It is well documented that helping children develop and sustain a physically active lifestyle requires children to become motivated. Many studies have been conducted in the past 2.5 decades on determinants and correlates for children and adolescents’ physical activity motivation. The findings have informed researchers and practitioners about motivation sources for children and effective strategies to motivate children in given physical activity settings. Built on the extensive knowledge base and theoretical platforms formed by these research studies, the purpose of this article is to take a look at the current research landscape and provide subjective thoughts about what we still need to know about children’s physical activity motivation. The product of this subjective thinking process rendered 10 potential questions for future research on children’s physical activity motivation in both in-school and out-of-school settings. These topics encompass those focusing on children’s physical activity motivation as a mental dispositional process, those conceptualizing the motivation as an outcome of person–environment interactions, and those attempting to dissect the motivation as an outcome of social–cultural influences and educational policies. It is hoped that the topics can serve researchers interested in children’s physical activity motivation as starting blocks from which they can extend their conceptual thinking and identify research questions that are personally meaningful. It is also hoped that the list of potential questions can be helpful to researchers in accomplishing the imperative and significant mission to motivate children to be physically active in the 21st century and beyond. PMID:24592774

  4. Research Experience and Agreement with Selected Ethics Principles from Canada's "Tri-Council Policy Statement--Ethical Conduct for Research Involving Humans"

    ERIC Educational Resources Information Center

    Fahy, Pat; Spencer, Bob

    2004-01-01

    An online survey was conducted of students, instructors, and researchers in distance education regarding principles for the ethical treatment of human research subjects. The study used an online questionnaire based on principles drawn from Canada's "Tri-Council Policy Statement, Ethical Conduct for Research Involving Humans" (TCPS,…

  5. 40 CFR 26.1303 - Submission of information pertaining to ethical conduct of completed human research.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ethical conduct of completed human research. 26.1303 Section 26.1303 Protection of Environment... on the Ethical Conduct of Completed Human Research § 26.1303 Submission of information pertaining to ethical conduct of completed human research. Any person who submits to EPA data derived from human...

  6. 40 CFR 26.1303 - Submission of information pertaining to ethical conduct of completed human research.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ethical conduct of completed human research. 26.1303 Section 26.1303 Protection of Environment... on the Ethical Conduct of Completed Human Research § 26.1303 Submission of information pertaining to ethical conduct of completed human research. Any person who submits to EPA data derived from human...

  7. 40 CFR 26.1303 - Submission of information pertaining to ethical conduct of completed human research.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ethical conduct of completed human research. 26.1303 Section 26.1303 Protection of Environment... on the Ethical Conduct of Completed Human Research § 26.1303 Submission of information pertaining to ethical conduct of completed human research. Any person who submits to EPA data derived from human...

  8. 40 CFR 26.1303 - Submission of information pertaining to ethical conduct of completed human research.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... ethical conduct of completed human research. 26.1303 Section 26.1303 Protection of Environment... on the Ethical Conduct of Completed Human Research § 26.1303 Submission of information pertaining to ethical conduct of completed human research. Any person who submits to EPA data derived from human...

  9. 40 CFR 26.1303 - Submission of information pertaining to ethical conduct of completed human research.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ethical conduct of completed human research. 26.1303 Section 26.1303 Protection of Environment... on the Ethical Conduct of Completed Human Research § 26.1303 Submission of information pertaining to ethical conduct of completed human research. Any person who submits to EPA data derived from human...

  10. Primary care research conducted in networks: getting down to business.

    PubMed

    Mold, James W

    2012-01-01

    This seventh annual practice-based research theme issue of the Journal of the American Board of Family Medicine highlights primary care research conducted in practice-based research networks (PBRNs). The issue includes discussion of (1) theoretical and methodological research, (2) health care research (studies addressing primary care processes), (3) clinical research (studies addressing the impact of primary care on patients), and (4) health systems research (studies of health system issues impacting primary care including the quality improvement process). We had a noticeable increase in submissions from PBRN collaborations, that is, studies that involved multiple networks. As PBRNs cooperate to recruit larger and more diverse patient samples, greater generalizability and applicability of findings lead to improved primary care processes.

  11. The university and the responsible conduct of research: who is responsible for what?

    PubMed

    Alfredo, Katherine; Hart, Hillary

    2011-09-01

    Research misconduct has been thoroughly discussed in the literature, but mainly in terms of definitions and prescriptions for proper conduct. Even when case studies are cited, they are generally used as a repository of "lessons learned." What has been lacking from this conversation is how the lessons of responsible conduct of research are imparted in the first place to graduate students, especially those in technical fields such as engineering. Nor has there been much conversation about who is responsible for what in training students in Responsible Conduct of Research or in allocating blame in cases of misconduct. This paper explores three seemingly disparate cases of misconduct-the 2004 plagiarism scandal at Ohio University; the famous Robert Millikan article of 1913, in which his reported data selection did not match his notebooks; and the 1990 fabrication scandal in Dr. Leroy Hood's research lab. Comparing these cases provides a way to look at the relationship between the graduate student (or trainee) and his/her advisor (a relationship that has been shown to be the most influential one for the student) as well as at possibly differential treatment for established researchers and researchers-in-training, in cases of misconduct. This paper reflects on the rights and responsibilities of research advisers and their students and offers suggestions for clarifying both those responsibilities and the particularly murky areas of research-conduct guidelines.

  12. Undergraduates Conducting Research Using High-Resolution Multibeam and Sidescan Sonar to Map and Characterize the Seabed: the BEAMS Program

    NASA Astrophysics Data System (ADS)

    Harris, M. S.; Sautter, L.

    2017-12-01

    The College of Charleston's BEnthic Acoustic Mapping and Survey (BEAMS) Program has just completed its 10th year of operation, and has proven to be remarkably effective at activating and maintaining undergraduate student interest in conducting research using sophisticated software, state-of-the-art instrumentation, enormous datasets, and significant experiential time. BEAMS students conduct research as part of a minimum 3-course sequence of marine geology-based content, marine geospatial software, and seafloor research courses. Over 140 students have completed the program, 56% of the graduated students remain active in the marine geospatial workforce or academic arenas. Forty-eight percent (48%) of those students are female. As undergraduates, students not only conduct independent research projects, but present their work at national conferences each year. Additionally, over 90 % of all "BEAMers" have been provided a 2-3 day at-sea experience on a dedicated BEAMS Program multibeam survey research cruise, and many students also volunteer as survey technicians aboard NOAA research vessels. Critical partnerships have developed with private industry to provide numerous collaborative opportunities and an employment/employer pipeline, as well as provision of software and hardware at many fiscal levels. Ongoing collaboration with the Marine Institute of Ireland and the National and Kapodistrian University of Athens has also provided valuable field opportunities and collaborative experiences. This talk will summarize the program while highlighting some of the key areas and topics investigated by students, including detailed geomorphologic studies of continental margins, submarine canyons, tectonic features and seamounts. Students also work with NOAA investigators to aid in the characterization of fish and deep coral habitats, and with BOEM researchers to study offshore windfield suitability and submerged cultural landscapes. Our sister program at the University of

  13. 14 CFR 1275.105 - Conduct of the OIG investigation of research misconduct.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... research misconduct. 1275.105 Section 1275.105 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275.105 Conduct of the OIG investigation of research misconduct. (a) The OIG shall make every reasonable effort to complete a NASA research misconduct investigation and issue...

  14. 14 CFR 1275.105 - Conduct of the OIG investigation of research misconduct.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... research misconduct. 1275.105 Section 1275.105 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275.105 Conduct of the OIG investigation of research misconduct. (a) The OIG shall make every reasonable effort to complete a NASA research misconduct investigation and issue...

  15. 14 CFR 1275.105 - Conduct of the OIG investigation of research misconduct.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... research misconduct. 1275.105 Section 1275.105 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275.105 Conduct of the OIG investigation of research misconduct. (a) The OIG shall make every reasonable effort to complete a NASA research misconduct investigation and issue...

  16. PLRP-3: Operational Perspectives of Conducting Science-Driven Extravehicular Activity with Communications Latency

    NASA Technical Reports Server (NTRS)

    Miller, Matthew J.; Lim, Darlene S. S.; Brady, Allyson; Cardman, Zena; Bell, Ernest; Garry, Brent; Reid, Donnie; Chappell, Steve; Abercromby, Andrew F. J.

    2016-01-01

    The Pavilion Lake Research Project (PLRP) is a unique platform where the combination of scientific research and human space exploration concepts can be tested in an underwater spaceflight analog environment. The 2015 PLRP field season was performed at Pavilion Lake, Canada, where science-driven exploration techniques focusing on microbialite characterization and acquisition were evaluated within the context of crew and robotic extravehicular activity (EVA) operations. The primary objectives of this analog study were to detail the capabilities, decision-making process, and operational concepts required to meet non-simulated scientific objectives during 5-minute one-way communication latency utilizing crew and robotic assets. Furthermore, this field study served as an opportunity build upon previous tests at PLRP, NASA Desert Research and Technology Studies (DRATS), and NASA Extreme Environment Mission Operations (NEEMO) to characterize the functional roles and responsibilities of the personnel involved in the distributed flight control team and identify operational constraints imposed by science-driven EVA operations. The relationship and interaction between ground and flight crew was found to be dependent on the specific scientific activities being addressed. Furthermore, the addition of a second intravehicular operator was found to be highly enabling when conducting science-driven EVAs. Future human spaceflight activities will need to cope with the added complexity of dynamic and rapid execution of scientific priorities both during and between EVA execution to ensure scientific objectives are achieved.

  17. Guidelines for conducting rigorous health care psychosocial cross-cultural/language qualitative research.

    PubMed

    Arriaza, Pablo; Nedjat-Haiem, Frances; Lee, Hee Yun; Martin, Shadi S

    2015-01-01

    The purpose of this article is to synthesize and chronicle the authors' experiences as four bilingual and bicultural researchers, each experienced in conducting cross-cultural/cross-language qualitative research. Through narrative descriptions of experiences with Latinos, Iranians, and Hmong refugees, the authors discuss their rewards, challenges, and methods of enhancing rigor, trustworthiness, and transparency when conducting cross-cultural/cross-language research. The authors discuss and explore how to effectively manage cross-cultural qualitative data, how to effectively use interpreters and translators, how to identify best methods of transcribing data, and the role of creating strong community relationships. The authors provide guidelines for health care professionals to consider when engaging in cross-cultural qualitative research.

  18. Assessing research activity and capacity of community-based organizations: development and pilot testing of an instrument.

    PubMed

    Humphries, Debbie L; Carroll-Scott, Amy; Mitchell, Leif; Tian, Terry; Choudhury, Shonali; Fiellin, David A

    2014-01-01

    Although awareness of the importance of the research capacity of community-based organizations (CBOs) is growing, a uniform framework of the research capacity domains within CBOs has not yet been developed. To develop a framework and instrument (the Community REsearch Activity assessment Tool [CREAT]) for assessing the research activity and capacity of CBOs that incorporates awareness of the different data collection and analysis priorities of CBOs. We conducted a review of existing tools for assessing research capacity to identify key capacity domains. Instrument items were developed through an iterative process with CBO representatives and community researchers. The CREAT was then pilot tested with 30 CBOs. The four primary domains of the CREAT framework include 1) organizational support for research, 2) generalizable experiences, 3) research specific experiences, and 4) funding. Organizations reported a high prevalence of activities in the research-specific experiences domain, including conducting literature reviews (70%), use of research terminology (83%), and primary data collection (100%). Respondents see research findings as important to improve program and service delivery, and to seek funds for new programs and services. Funders, board members, and policymakers are the most important dissemination audiences. The work reported herein advances the field of CBO research capacity by developing a systematic framework for assessing research activity and capacity relevant to the work of CBOs, and by developing and piloting an instrument to assess activity in these domains.

  19. Integrating a framework for conducting public health systems research into statewide operations-based exercises to improve emergency preparedness

    PubMed Central

    2012-01-01

    Background Due to the uncommon nature of large-scale disasters and emergencies, public health practitioners often turn to simulated emergencies, known as “exercises”, for preparedness assessment and improvement. Under the right conditions, exercises can also be used to conduct original public health systems research. This paper describes the integration of a research framework into a statewide operations-based exercise program in California as a systems-based approach for studying public health emergency preparedness and response. Methods We developed a research framework based on the premise that operations-based exercises conducted by medical and public health agencies can be described using epidemiologic concepts. Using this framework, we conducted a survey of key local and regional medical and health agencies throughout California following the 2010 Statewide Medical and Health Exercise. The survey evaluated: (1) the emergency preparedness capabilities activated and functions performed in response to the emergency scenario, and (2) the major challenges to inter-organizational communications and information management. Results Thirty-five local health departments (LHDs), 24 local emergency medical services (EMS) agencies, 121 hospitals, and 5 Regional Disaster Medical and Health Coordinators/Specialists (RDMHC) responded to our survey, representing 57%, 77%, 26% and 83%, respectively, of target agencies in California. We found two sets of response capabilities were activated during the 2010 Statewide Exercise: a set of core capabilities that were common across all agencies, and a set of agency-specific capabilities that were more common among certain agency types. With respect to one response capability in particular, inter-organizational information sharing, we found that the majority of respondents’ comments were related to the complete or partial failure of communications equipment or systems. Conclusions Using the 2010 Statewide Exercise in California

  20. Conducting Research in a Medical Science Museum: Lessons Learned from Collaboration between Researchers and Museum Educators

    ERIC Educational Resources Information Center

    Durksen, Tracy L.; Martin, Andrew J.; Burns, Emma C.; Ginns, Paul; Williamson, Derek; Kiss, Julia

    2017-01-01

    Museums promote co-learning through the construction of a social community, one that involves personal, physical, and sociocultural contexts. As researchers and museum educators, we report some of our contextual reflections and recommendations that emerged from our collaborative learning experience of conducting research in a medical science…

  1. Space Research, Education, and Related Activities in the Space Sciences

    NASA Technical Reports Server (NTRS)

    Black, David; Marshall, Frank (Technical Monitor)

    2002-01-01

    The Universities Space Research Association received an award of Cooperative Agreement NCC5-356 on September 29, 1998. The mission of this activity, known as the Cooperative Program in Space Sciences (CPSS), is to conduct space science research and leading-edge instrumentation and technology development, enable research by the space sciences communities, and to expedite the effective dissemination of space science research, technology, data, and information to the educational community and the general public. To fulfill this mission, USRA recruits and maintains a staff of scientific researchers, operates a series of guest investigator facilities, organizes scientific meetings and workshops, and encourages various interactions with students and university faculty members.

  2. Space Research, Education, and Related Activities In the Space Sciences

    NASA Technical Reports Server (NTRS)

    Black, David

    2002-01-01

    The mission of this activity, known as the Cooperative Program in Space Sciences (CPSS), is to conduct space science research and leading-edge instrumentation and technology development, enable research by the space sciences communities, and to expedite the effective dissemination of space science research, technology, data, and information to the educational community and the general public. To fulfill this mission, the Universities Space Research Association (USRA) recruits and maintains a staff of scientific researchers, operates a series of guest investigator facilities, organizes scientific meetings and workshops, and encourages various interactions with students and university faculty members. This paper is the final report from this now completed Cooperative Agreement.

  3. Space Research, Education, and Related Activities in the Space Sciences

    NASA Technical Reports Server (NTRS)

    2000-01-01

    The Universities Space Research Association received an award of Cooperative Agreement #NCC5-356 on September 29, 1998. The mission of this activity, know as the Cooperative Program in Space Sciences (CPSS), is to conduct space science research and leading-edge instrumentation and technology development, enable research by the space sciences communities, and to expedite the effective dissemination of space science research, technology, data, and information to the educational community and the general public. To fulfill this mission, USRA recruits and maintains a staff of scientific researchers, operates a series of guest investigator facilities, organizes scientific meetings and workshops, and encourages various interactions with students and university faculty members.

  4. Responsible Conduct of Research in Communication Sciences and Disorders: Faculty and Student Perceptions

    ERIC Educational Resources Information Center

    Minifie, Fred D.; Robey, Randall R.; Horner, Jennifer; Ingham, Janis C.; Lansing, Charissa; McCartney, James H.; Alldredge, Elham-Eid; Slater, Sarah C.; Moss, Sharon E.

    2011-01-01

    Purpose: Two Web-based surveys (Surveys I and II) were used to assess perceptions of faculty and students in Communication Sciences and Disorders (CSD) regarding the responsible conduct of research (RCR). Method: Survey questions addressed 9 RCR domains thought important to the responsible conduct of research: (a) human subjects protections; (b)…

  5. Research Ethics I: Responsible Conduct of Research (RCR)--Historical and Contemporary Issues Pertaining to Human and Animal Experimentation

    ERIC Educational Resources Information Center

    Horner, Jennifer; Minifie, Fred D.

    2011-01-01

    Purpose: In this series of articles--"Research Ethics I", "Research Ethics II", and "Research Ethics III"--the authors provide a comprehensive review of the 9 core domains for the responsible conduct of research (RCR) as articulated by the Office of Research Integrity. In "Research Ethics I", they present a historical overview of the evolution of…

  6. 26 CFR 1.355-3 - Active conduct of a trade or business.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 4 2011-04-01 2011-04-01 false Active conduct of a trade or business. 1.355-3... TAX (CONTINUED) INCOME TAXES Effects on Shareholders and Security Holders § 1.355-3 Active conduct of... section 355 only if— (i) The distributing and the controlled corporations are each engaged in the active...

  7. Research Activities for Nuclear Power Plant Aging Promoted by PLEC, JAPEIC, Japan

    NASA Astrophysics Data System (ADS)

    Maeda, Noriyoshi; Tajima, Kenichi

    In order to perform research activity for aging countermeasure of nuclear power plant effectively, Plant Life Engineering Center (PLEC) was established in Japan Power Engineering and Inspection Corporation (JAPEIC) in April 2000 sponsored by Ministry of International Trade and Industry (MITI, presently METI). Outlined activities of PLEC are as follows. Results of technical survey for research and development for aging phenomena have been summarized in a table (Research Map) categorizing them into “inspection and monitoring”, “evaluation method for aging” and “preventive maintenances and refurbishment”. Necessary research themes have been extracted from the Research Map consulting to experts of the specified research area and they are summarized into Medium and Long-term Research Perspective (Research Perspective), which contains prioritized research themes and outlined specification of each theme. Several new research themes proposed by various organizations and selected by PLEC as effective for the regulation activities are identified and proposed to be funded by METI every year. This paper also provides outlines and obtained results of aging related research projects currently conducted by JAPEIC sponsored by METI.

  8. Conducting Qualitative Research on Stigmatizing Conditions with Military Populations

    PubMed Central

    Lincoln, Martha L.; Ames, Genevieve M.; Moore, Roland S.

    2016-01-01

    This article addresses the conduct of qualitative research regarding sensitive or stigmatizing topics with military populations, and provides suggestions for implementing culturally responsive and effective data collection with these groups. Given high rates of underreporting of sensitive and stigmatizing conditions in the military, qualitative methods have potential to shed light on phenomena that are not well understood. Drawing on a study of U.S. Army National Guard personnel by civilian anthropologists, we present lessons learned and argue that the value of similar studies can be maximized by culturally responsive research design. PMID:27722033

  9. Designing and Proposing Your Research Project. Concise Guides to Conducting Behavioral, Health, and Social Science Research Series

    ERIC Educational Resources Information Center

    Urban, Jennifer Brown; van Eeden-Moorefield, Bradley Matheus

    2017-01-01

    Designing your own study and writing your research proposal takes time, often more so than conducting the study. This practical, accessible guide walks you through the entire process. You will learn to identify and narrow your research topic, develop your research question, design your study, and choose appropriate sampling and measurement…

  10. Conducting Research with LGB People of Color: Methodological Challenges and Strategies

    ERIC Educational Resources Information Center

    DeBlaere, Cirleen; Brewster, Melanie E.; Sarkees, Anthony; Moradi, Bonnie

    2010-01-01

    Methodological barriers have been highlighted as a primary reason for the limited research with lesbian, gay, and bisexual (LGB) people of color. Thus, strategies for anticipating and addressing potential methodological barriers are needed. To address this need, this article discusses potential challenges associated with conducting research with…

  11. Conducting Research as a Visiting Scientist in a Women’s Prison

    PubMed Central

    Byrne, Mary Woods

    2006-01-01

    Incarcerated populations have disparities in health risks and illness conditions meriting study, but the history of prison research is marred by unethical conduct. Ethical participation strategies are discussed in the context of studies implemented by the author in a state prison system. This study used ethnographic approaches, observed adherence to federal and institutional review board regulations and corrections department directives, and maintained continuous communication with vested interests to provide entry and long-term access for studies on female prisoners and their civilian infants. A culture clash between the punitive restrictive environment that serves the custody–control–care mission of corrections systems and the open inquiry environment needed for conduct of health research exists. Federal regulations protect prisoners as human subjects but additional vigilance and communication by researchers are required. Gaining and maintaining access to prison inmates for nursing research are leadership challenges that can be met within the caring and collaborative paradigm of nursing. PMID:16061169

  12. Procedure versus process: ethical paradigms and the conduct of qualitative research.

    PubMed

    Pollock, Kristian

    2012-09-27

    Research is fundamental to improving the quality of health care. The need for regulation of research is clear. However, the bureaucratic complexity of research governance has raised concerns that the regulatory mechanisms intended to protect participants now threaten to undermine or stifle the research enterprise, especially as this relates to sensitive topics and hard to reach groups. Much criticism of research governance has focused on long delays in obtaining ethical approvals, restrictions imposed on study conduct, and the inappropriateness of evaluating qualitative studies within the methodological and risk assessment frameworks applied to biomedical and clinical research. Less attention has been given to the different epistemologies underlying biomedical and qualitative investigation. The bioethical framework underpinning current regulatory structures is fundamentally at odds with the practice of emergent, negotiated micro-ethics required in qualitative research. The complex and shifting nature of real world settings delivers unanticipated ethical issues and (occasionally) genuine dilemmas which go beyond easy or formulaic 'procedural' resolution. This is not to say that qualitative studies are 'unethical' but that their ethical nature can only be safeguarded through the practice of 'micro-ethics' based on the judgement and integrity of researchers in the field. This paper considers the implications of contrasting ethical paradigms for the conduct of qualitative research and the value of 'empirical ethics' as a means of liberating qualitative (and other) research from an outmoded and unduly restrictive research governance framework based on abstract prinicipalism, divorced from real world contexts and values.

  13. Obtaining active parental consent for school-based research: a guide for researchers.

    PubMed

    Wolfenden, Luke; Kypri, Kypros; Freund, Megan; Hodder, Rebecca

    2009-06-01

    Schools increasingly require researchers to obtain active parental consent for students to participate in health research. We sought to identify effective strategies for the recruitment of child research participants through schools. A search of Medline, PsycINFO, Educational Resources Information Center, ProQuest 5000 and the Cochrane Library electronic databases was conducted for the period 1988 to 2008. The review found evidence that the following strategies may be effective in enhancing participation rates: 1) promotion of the research to school principals, teachers, parents and students; 2) dissemination of study information using methods allowing direct contact with parents (i.e. telephone or face-to-face); 3) provision of incentives to teachers, students and at a class level; 4) making reminder contacts; and 5) having a member of the research team co-ordinate and closely monitor the recruitment process. Application of these strategies should reduce the risk of non-response and other biases that result from selective non-participation. Further randomised controlled trials of these and other strategies are required to strengthen the evidence base.

  14. Problems of Conducting Research in Organizations: The Case of Police Departments.

    ERIC Educational Resources Information Center

    Lefkowitz, Joel

    This paper presents a description of police research problems in such fashion that it could be generalized to other types of organizations. A two-dimensional taxonomy of problems in conducting psychological research in police departments is discussed. The first dimension concerns generality-uniqueness of the problem, relative to formal…

  15. Conducting rapid, relevant research: lessons learned from the My Own Health Report project.

    PubMed

    Glasgow, Russell E; Kessler, Rodger S; Ory, Marcia G; Roby, Dylan; Gorin, Sherri Sheinfeld; Krist, Alex

    2014-08-01

    The lengthy and uncertain translation of research into clinical practice is well documented. Much of the current "gold standard" clinical research is slow, expensive, and lacks perceived relevance for practitioners and decision makers. In contrast, we summarize experiences conducting the My Own Health Report (MOHR) project to collect and address patient reported measures using principles of rapid, relevant pragmatic research. The methods used for rapid design and fielding of the MOHR project to improve attention to health behaviors and mental health are detailed. Within the multisite, pragmatic, implementation-focused MOHR study, we describe the four phases of the research and the key decisions made and actions taken within each. We provide concrete examples of how relevant research can be conducted transparently to rapidly provide information to practitioners. Data were collected and analyzed in 2013. The multisite (seven research centers partnered with 18 clinics) cluster randomized pragmatic delayed intervention trial was conducted in less than 18 months from receipt of funding applications to completion of data collection. Phases that were especially accelerated included funding and review, and recruitment and implementation. Conducting complex studies rapidly and efficiently is a realistic goal. Key lessons learned for prevention research include use of existing research networks; use of web-based assessment/feedback tools that are tailored to fit local needs; engaging relevant stakeholders early on and throughout the process to minimize need for redesign; and making pragmatic decisions that balance internal and external validity concerns rather than waiting for perfect solutions. Published by Elsevier Inc.

  16. Ethical challenges in conducting clinical research in lung cancer

    PubMed Central

    Tod, Angela M.

    2016-01-01

    The article examines ethical challenges that arise with clinical lung cancer research focusing on design, recruitment, conduct and dissemination. Design: problems related to equipoise can arise in lung cancer studies. Equipoise is an ethics precondition for RCTs and exists where there is insufficient evidence to decide which of two or more treatments is best. Difficulties arise in deciding what level of uncertainty constitutes equipoise and who should be in equipoise, for example, patients might not be even where clinicians are. Patient and public involvement (PPI) can reduce but not remove the problems. Recruitment: (I) lung cancer studies can be complex, making it difficult to obtain good quality consent. Some techniques can help, such as continuous consent. But researchers should not expect consent to be the sole protection for participants’ welfare. This protection is primarily done elsewhere in the research process, for example, in ethics review; (II) the problem of desperate volunteers: some patients only consent to a trial because it gives them a 50/50 option of the treatment they want and can be disappointed or upset if randomised to the other arm. This is not necessarily unfair, given clinical equipoise. However, it should be avoided where possible, for example, by using alternative trial designs; (III) the so-called problem of therapeutic misconception: this is the idea that patients are mistaken if they enter trials believing this to be in their clinical best interest. We argue the problem is misconceived and relates only to certain health systems. Conduct: lung cancer trials face standard ethical challenges with regard to trial conduct. PPI could be used in decisions about criteria for stopping rules. Dissemination: as in other trial areas, it is important that all results, including negative ones, are reported. We argue also that the role of PPI with regard to dissemination is currently under-developed. PMID:27413698

  17. Practice-based research networks (PBRNs) are promising laboratories for conducting dissemination and implementation research.

    PubMed

    Heintzman, John; Gold, Rachel; Krist, Alexander; Crosson, Jay; Likumahuwa, Sonja; DeVoe, Jennifer E

    2014-01-01

    Dissemination and implementation science addresses the application of research findings in varied health care settings. Despite the potential benefit of dissemination and implementation work to primary care, ideal laboratories for this science have been elusive. Practice-based research networks (PBRNs) have a long history of conducting research in community clinical settings, demonstrating an approach that could be used to execute multiple research projects over time in broad and varied settings. PBRNs also are uniquely structured and increasingly involved in pragmatic trials, a research design central to dissemination and implementation science. We argue that PBRNs and dissemination and implementation scientists are ideally suited to work together and that the collaboration of these 2 groups will yield great value for the future of primary care and the delivery of evidence-based health care. © Copyright 2014 by the American Board of Family Medicine.

  18. 14 CFR 1275.105 - Conduct of the OIG investigation of research misconduct.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... misconduct. 1275.105 Section 1275.105 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275.105 Conduct of the OIG investigation of research misconduct. (a) The OIG shall make every reasonable effort to complete a NASA research misconduct investigation and issue a report...

  19. Logistical Challenges and Opportunities for Conducting Peer Nomination Research in Schools

    ERIC Educational Resources Information Center

    Mayeux, Lara; Kraft, Caroline

    2017-01-01

    Although conducting psychological research within schools has always required effort, persistence, and the careful navigation of various interests, there is a consensus among child and adolescent researchers that, over the past 2 decades, it has become increasingly difficult to collect data within schools. In this chapter, we lay out common and…

  20. Methodological Issues and Practical Problems in Conducting Research on Abused Children.

    ERIC Educational Resources Information Center

    Kinard, E. Milling

    In order to inform policy and programs, research on child abuse must be not only methodologically rigorous, but also practically feasible. However, practical problems make child abuse research difficult to conduct. Definitions of abuse must be explicit and different types of abuse must be assessed separately. Study samples should be as…

  1. Physical Activity Breaks and Student Learning: A Teacher-Research Project

    ERIC Educational Resources Information Center

    Camahalan, Faye Marsha G.; Ipock, Amanda R.

    2015-01-01

    This study is a teacher initiated action research. The purpose is to improve student learning in math using physical activity breaks during classroom lessons. The study was conducted by tracking the results of ten 5th grade students for a period of one week. Using anecdotal notes, students showed improvement on attentiveness during class…

  2. Microbial Activity Influences Electrical Conductivity of Biofilm Anode

    EPA Science Inventory

    This study assessed the conductivity of a Geobacter-enriched biofilm anode along with biofilm activity in a microbial electrochemical cell (MxC) equipped with two gold anodes (25 mM acetate medium), as different proton gradients were built throughout the biofilm. There was no pH ...

  3. Computer Based Procedures for Field Workers - FY16 Research Activities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Oxstrand, Johanna; Bly, Aaron

    The Computer-Based Procedure (CBP) research effort is a part of the Light-Water Reactor Sustainability (LWRS) Program, which provides the technical foundations for licensing and managing the long-term, safe, and economical operation of current nuclear power plants. One of the primary missions of the LWRS program is to help the U.S. nuclear industry adopt new technologies and engineering solutions that facilitate the continued safe operation of the plants and extension of the current operating licenses. One area that could yield tremendous savings in increased efficiency and safety is in improving procedure use. A CBP provides the opportunity to incorporate context-driven jobmore » aids, such as drawings, photos, and just-in-time training. The presentation of information in CBPs can be much more flexible and tailored to the task, actual plant condition, and operation mode. The dynamic presentation of the procedure will guide the user down the path of relevant steps, thus minimizing time spent by the field worker to evaluate plant conditions and decisions related to the applicability of each step. This dynamic presentation of the procedure also minimizes the risk of conducting steps out of order and/or incorrectly assessed applicability of steps. This report provides a summary of the main research activities conducted in the Computer-Based Procedures for Field Workers effort since 2012. The main focus of the report is on the research activities conducted in fiscal year 2016. The activities discussed are the Nuclear Electronic Work Packages – Enterprise Requirements initiative, the development of a design guidance for CBPs (which compiles all insights gained through the years of CBP research), the facilitation of vendor studies at the Idaho National Laboratory (INL) Advanced Test Reactor (ATR), a pilot study for how to enhance the plant design modification work process, the collection of feedback from a field evaluation study at Plant Vogtle, and path forward to

  4. An overview of Japanese CELSS research activities

    NASA Technical Reports Server (NTRS)

    Nitta, Keiji

    1987-01-01

    Development of Controlled Ecological Life Support System (CELSS) technology is inevitable for future long duration stays of human beings in space, for lunar base construction and for manned Mars flight programs. CELSS functions can be divided into 2 categories, Environmental Control and Material Recycling. Temperature, humidity, total atmospheric pressure and partial pressure of oxygen and carbon dioxide, necessary for all living things, are to be controlled by the environment control function. This function can be performed by technologies already developed and used as the Environment Control Life Support System (ECLSS) of Space Shuttle and Space Station. As for material recycling, matured technologies have not yet been established for fully satisfying the specific metabolic requirements of each living thing including human beings. Therefore, research activities for establishing CELSS technology should be focused on material recycling technologies using biological systems such as plants and animals and physico-chemical systems, for example, a gas recycling system, a water purifying and recycling system and a waste management system. Japanese research activities were conducted and will be continued accordingly.

  5. Procedure versus process: ethical paradigms and the conduct of qualitative research

    PubMed Central

    2012-01-01

    Background Research is fundamental to improving the quality of health care. The need for regulation of research is clear. However, the bureaucratic complexity of research governance has raised concerns that the regulatory mechanisms intended to protect participants now threaten to undermine or stifle the research enterprise, especially as this relates to sensitive topics and hard to reach groups. Discussion Much criticism of research governance has focused on long delays in obtaining ethical approvals, restrictions imposed on study conduct, and the inappropriateness of evaluating qualitative studies within the methodological and risk assessment frameworks applied to biomedical and clinical research. Less attention has been given to the different epistemologies underlying biomedical and qualitative investigation. The bioethical framework underpinning current regulatory structures is fundamentally at odds with the practice of emergent, negotiated micro-ethics required in qualitative research. The complex and shifting nature of real world settings delivers unanticipated ethical issues and (occasionally) genuine dilemmas which go beyond easy or formulaic ‘procedural’ resolution. This is not to say that qualitative studies are ‘unethical’ but that their ethical nature can only be safeguarded through the practice of ‘micro-ethics’ based on the judgement and integrity of researchers in the field. Summary This paper considers the implications of contrasting ethical paradigms for the conduct of qualitative research and the value of ‘empirical ethics’ as a means of liberating qualitative (and other) research from an outmoded and unduly restrictive research governance framework based on abstract prinicipalism, divorced from real world contexts and values. PMID:23016663

  6. Ethical Issues in Conducting Research With Deaf Populations

    PubMed Central

    Schlehofer, Deirdre; Thew, Denise

    2013-01-01

    Deaf American Sign Language (ASL) users represent a small population at risk for marginalization from research and surveillance activities resulting from cultural, language, and ethical challenges. The Deaf community’s view of deafness as a cultural identity, rather than a disability, contradicts the medical community’s perception of deafness as a disease or deficiency in need of correction or elimination. These differences continue to have significant cultural and social implications within the Deaf community, resulting in mistrust of research opportunities. Two particularly contentious ethical topics for the Deaf community are the absence of community representation in genetic research and the lack of accessible informed consents and research materials. This article outlines a series of innovative strategies and solutions to these issues, including the importance of community representation and collaboration with researchers studying deaf populations. PMID:24134363

  7. Conducting perception research over the internet: a tutorial review.

    PubMed

    Woods, Andy T; Velasco, Carlos; Levitan, Carmel A; Wan, Xiaoang; Spence, Charles

    2015-01-01

    This article provides an overview of the recent literature on the use of internet-based testing to address important questions in perception research. Our goal is to provide a starting point for the perception researcher who is keen on assessing this tool for their own research goals. Internet-based testing has several advantages over in-lab research, including the ability to reach a relatively broad set of participants and to quickly and inexpensively collect large amounts of empirical data, via services such as Amazon's Mechanical Turk or Prolific Academic. In many cases, the quality of online data appears to match that collected in lab research. Generally-speaking, online participants tend to be more representative of the population at large than those recruited for lab based research. There are, though, some important caveats, when it comes to collecting data online. It is obviously much more difficult to control the exact parameters of stimulus presentation (such as display characteristics) with online research. There are also some thorny ethical elements that need to be considered by experimenters. Strengths and weaknesses of the online approach, relative to others, are highlighted, and recommendations made for those researchers who might be thinking about conducting their own studies using this increasingly-popular approach to research in the psychological sciences.

  8. Conducting perception research over the internet: a tutorial review

    PubMed Central

    Velasco, Carlos; Levitan, Carmel A.; Wan, Xiaoang; Spence, Charles

    2015-01-01

    This article provides an overview of the recent literature on the use of internet-based testing to address important questions in perception research. Our goal is to provide a starting point for the perception researcher who is keen on assessing this tool for their own research goals. Internet-based testing has several advantages over in-lab research, including the ability to reach a relatively broad set of participants and to quickly and inexpensively collect large amounts of empirical data, via services such as Amazon’s Mechanical Turk or Prolific Academic. In many cases, the quality of online data appears to match that collected in lab research. Generally-speaking, online participants tend to be more representative of the population at large than those recruited for lab based research. There are, though, some important caveats, when it comes to collecting data online. It is obviously much more difficult to control the exact parameters of stimulus presentation (such as display characteristics) with online research. There are also some thorny ethical elements that need to be considered by experimenters. Strengths and weaknesses of the online approach, relative to others, are highlighted, and recommendations made for those researchers who might be thinking about conducting their own studies using this increasingly-popular approach to research in the psychological sciences. PMID:26244107

  9. Annual Report for 2003 Wild Horse Research and Field Activities

    USGS Publications Warehouse

    Ransom, Jason; Singer, Francis J.; Zeigenfuss, Linda C.

    2004-01-01

    This report is meant to highlight the activities of the 2003 field season, as well as to provide a general overview of the data collected. More in-depth data analysis will be conducted following the conclusion of each I phase of the research project, and in many cases will not be possible until several seasons of data are collected.

  10. Nigerian pharmacists’ self-perceived competence and confidence to plan and conduct pharmacy practice research

    PubMed Central

    Usman, Mohammad N.; Umar, Muhammad D.

    2018-01-01

    Background: Recent studies have revealed that pharmacists have interest in conducting research. However, lack of confidence is a major barrier. Objective: This study evaluated pharmacists’ self-perceived competence and confidence to plan and conduct health-related research. Method: This cross sectional study was conducted during the 89th Annual National Conference of the Pharmaceutical Society of Nigeria in November 2016. An adapted questionnaire was validated and administered to 200 pharmacist delegates during the conference. Result: Overall, 127 questionnaires were included in the analysis. At least 80% of the pharmacists had previous health-related research experience. Pharmacist’s competence and confidence scores were lowest for research skills such as: using software for statistical analysis, choosing and applying appropriate inferential statistical test and method, and outlining detailed statistical plan to be used in data analysis. Highest competence and confidence scores were observed for conception of research idea, literature search and critical appraisal of literature. Pharmacists with previous research experience had higher competence and confidence scores than those with no previous research experience (p<0.05). The only predictor of moderate-to-extreme self-competence and confidence was having at least one journal article publication during the last 5 years. Conclusion: Nigerian pharmacists indicated interest to participate in health-related research. However, self-competence and confidence to plan and conduct research were low. This was particularly so for skills related to statistical analysis. Training programs and building of Pharmacy Practice Research Network are recommended to enhance pharmacist’s research capacity. PMID:29619141

  11. ECUT: Energy Conversion and Utilization Technologies program - Biocatalysis research activity

    NASA Technical Reports Server (NTRS)

    Wilcox, R.

    1984-01-01

    The activities of the Biocatalysis Research Activity are organized into the Biocatalysis and Molecular Modeling work elements and a supporting planning and analysis function. In the Biocatalysis work element, progress is made in developing a method for stabilizing genetically engineered traits in microorganisms, refining a technique for monitoring cells that are genetically engineered, and identifying strains of fungi for highly efficient preprocessing of biomass for optimizing the efficiency of bioreactors. In the Molecular Modeling work element, a preliminary model of the behavior of enzymes is developed. A preliminary investigation of the potential for synthesizing enzymes for use in electrochemical processes is completed. Contact with industry and universities is made to define key biocatalysis technical issues and to broaden the range of potential participants in the activity. Analyses are conducted to identify and evaluate potential concepts for future research funding.

  12. The CELSS research program - A brief review of recent activities

    NASA Technical Reports Server (NTRS)

    Macelroy, R. D.; Tremor, J.; Bubenheim, D. L.; Gale, J.

    1989-01-01

    The history of the Controlled Ecological Life Support System program, initiated by NASA in the late 1970s to explore the use of bioregenerative methods of life support, is reviewed. The project focused on examining the process involved in converting inorganic minerals and gases into life support materials using sunlight as the primary energy source. The research, planning, and technological development required by the CELSS program and conducted at NASA field centers, at various universities, and by commercial organizations are reviewed. Research activities at universities have focused upon exploring methods of reducing the size of the system, reducing system power requirements, understanding issues that are associated with its long-term stability, and identifying new technologies that might be useful in improving its efficiency. Research activities at Ames research center have focused on the use of common duckweed as a high biomass-producing plant, which is high in protein and on waste processing.

  13. How Not to Let Secrets Out When Conducting Qualitative Research With Dyads.

    PubMed

    Ummel, Deborah; Achille, Marie

    2016-05-01

    Confidentiality is one of the cornerstones of research involving human participants. Researchers are the frontline gatekeepers of their participants' right to confidentiality, and situations can arise that challenge this responsibility. This is the case when individuals who have shared a common experience (i.e., dyads) are interviewed separately, but interview results are disseminated within the context of dyads. Based on our experience of conducting research with dyads and given how little literature is available to serve as guide, we set out to write this article to share the knowledge we acquired and the solutions we found. We will describe both the ethical challenges and the methodological decisions involved in conducting qualitative research with dyads. The article also describes different modalities of dyadic analysis, their benefits and drawbacks. This endeavor seems especially relevant as research with dyads is emerging in several domains involving couples, families, caregivers and health. © The Author(s) 2016.

  14. Visible-light active conducting polymer nanostructures with superior photocatalytic activity

    NASA Astrophysics Data System (ADS)

    Ghosh, Srabanti; Kouame, Natalie Amoin; Remita, Samy; Ramos, Laurence; Goubard, Fabrice; Aubert, Pierre-Henri; Dazzi, Alexandre; Deniset-Besseau, Ariane; Remita, Hynd

    2015-12-01

    The development of visible-light responsive photocatalysts would permit more efficient use of solar energy, and thus would bring sustainable solutions to many environmental issues. Conductive polymers appear as a new class of very active photocatalysts under visible light. Among them poly(3,4-ethylenedioxythiophene) (PEDOT) is one of the most promising conjugated polymer with a wide range of applications. PEDOT nanostructures synthesized in soft templates via chemical oxidative polymerization demonstrate unprecedented photocatalytic activities for water treatment without the assistance of sacrificial reagents or noble metal co-catalysts and turn out to be better than TiO2 as benchmark catalyst. The PEDOT nanostructures exhibit a narrow band gap (E = 1.69 eV) and are characterized by excellent ability to absorb light in visible and near infrared region. The novel PEDOT-based photocatalysts are very stable with cycling and can be reused without appreciable loss of activity. Interestingly, hollow micrometric vesicular structures of PEDOT are not effective photocatalysts as compared to nanometric spindles suggesting size and shape dependent photocatalytic properties. The visible-light active photocatalytic properties of the polymer nanostructures present promising applications in solar light harvesting and broader fields.

  15. Ethical Considerations for Conducting Health Disparities Research in Community Health Centers: A Social-Ecological Perspective

    PubMed Central

    Scott, Ebony; Melendez, Jennifer; Rodriguez, Anna; Ramos, Rosio; Kanna, Balavenkatesh; Michelen, Walid

    2013-01-01

    Community health centers (CHCs) provide optimal research settings. They serve a high-risk, medically underserved population in the greatest need of intervention. Low socioeconomic status renders this population particularly vulnerable to research misconduct. Traditional principles of research ethics are often applied to participants only. The social-ecological model offers a comprehensive framework for applying these principles across multiple levels (participants, providers, organizations, communities, and policy). Our experience with the Trial Using Motivational Interviewing, Positive Affect and Self-Affirmation in African-Americans with Hypertension, a randomized trial conducted in CHCs, led us to propose a new platform for discussing research ethics; examine the social, community, and political factors surrounding research conducted in CHCs; and recommend how future research should be conducted in such settings. PMID:24134347

  16. Ethical considerations for conducting health disparities research in community health centers: a social-ecological perspective.

    PubMed

    Boutin-Foster, Carla; Scott, Ebony; Melendez, Jennifer; Rodriguez, Anna; Ramos, Rosio; Kanna, Balavenkatesh; Michelen, Walid

    2013-12-01

    Community health centers (CHCs) provide optimal research settings. They serve a high-risk, medically underserved population in the greatest need of intervention. Low socioeconomic status renders this population particularly vulnerable to research misconduct. Traditional principles of research ethics are often applied to participants only. The social-ecological model offers a comprehensive framework for applying these principles across multiple levels (participants, providers, organizations, communities, and policy). Our experience with the Trial Using Motivational Interviewing, Positive Affect and Self-Affirmation in African-Americans with Hypertension, a randomized trial conducted in CHCs, led us to propose a new platform for discussing research ethics; examine the social, community, and political factors surrounding research conducted in CHCs; and recommend how future research should be conducted in such settings.

  17. A Survey of Marketing and Market Research Activities in Two and Four-Year Colleges and Universities.

    ERIC Educational Resources Information Center

    Smith, Janet D.; And Others

    A survey of marketing and market research activities in large, urban, two- and four-year colleges was conducted to identify the nature of marketing problems faced by institutions; current and preferred emphasis placed on market research activities; modes of assessing the needs of target groups and developing appropriate programs; the location of…

  18. Overcoming practical challenges to conducting clinical research in the inpatient stroke rehabilitation setting.

    PubMed

    Campbell, Grace B; Skidmore, Elizabeth R; Whyte, Ellen M; Matthews, Judith T

    2015-10-01

    There is a shortage of published empirical studies conducted in acute inpatient stroke rehabilitation, though such studies are greatly needed in order to shed light on the most efficacious inpatient stroke rehabilitation interventions. The inherent challenges of inpatient research may dissuade researchers from undertaking this important work. This paper describes our institution's experience devising practical solutions to research barriers in this setting. Through concentrated efforts to overcome research barriers, such as by cultivating collaborative relationships and capitalizing on unanticipated benefits, we successfully facilitated conduct of five simultaneous inpatient stroke studies. Tangible benefits realized include increased effectiveness of research participant identification and enrollment, novel collaborative projects, innovative clinical care initiatives, and enhanced emotional and practical support for patients and their families. We provide recommendations based on lessons learned during our experience, and discuss benefits of this collaboration for our research participants, clinical staff, and the research team.

  19. Research Involving Health Providers and Managers: Ethical Issues Faced by Researchers Conducting Diverse Health Policy and Systems Research in Kenya.

    PubMed

    Molyneux, Sassy; Tsofa, Benjamin; Barasa, Edwine; Nyikuri, Mary Muyoka; Waweru, Evelyn Wanjiku; Goodman, Catherine; Gilson, Lucy

    2016-12-01

    There is a growing interest in the ethics of Health Policy and Systems Research (HPSR), and especially in areas that have particular ethical salience across HPSR. Hyder et al (2014) provide an initial framework to consider this, and call for more conceptual and empirical work. In this paper, we respond by examining the ethical issues that arose for researchers over the course of conducting three HPSR studies in Kenya in which health managers and providers were key participants. All three studies involved qualitative work including observations and individual and group interviews. Many of the ethical dilemmas researchers faced only emerged over the course of the fieldwork, or on completion, and were related to interactions and relationships between individuals operating at different levels or positions in health/research systems. The dilemmas reveal significant ethical challenges for these forms of HPSR, and show that potential 'solutions' to dilemmas often lead to new issues and complications. Our experiences support the value of research ethics frameworks, and suggest that these can be enriched by incorporating careful consideration of context embedded social relations into research planning and conduct. Many of these essential relational elements of ethical practice, and of producing quality data, are given stronger emphasis in social science research ethics than in epidemiological, clinical or biomedical research ethics, and are particularly relevant where health systems are understood as social and political constructs. We conclude with practical and research implications. © 2016 The Authors Developing World Bioethics Published by John Wiley & Sons Ltd.

  20. Music therapists' research activity and utilization barriers: a survey of the membership.

    PubMed

    Waldon, Eric G

    2015-01-01

    Music therapists have access to a rapidly expanding body of research supporting the use of music-based interventions. What is not known is the extent to which music therapists access these resources and what factors may prevent them from incorporating research findings into clinical work. After constructing the Music Therapists' Research Activity and Utilization Barrier (MTRAUB) database, the purposes of this study involved: assessing the extent to which American Music Therapy Association (AMTA) members engage in certain research-related activities; and identifying respondents' perceived barriers to integrating research into clinical practice. This study employed a quantitative, non-experimental approach using an online survey. Respondents included professional, associate, student/graduate student, retired, inactive, and honorary life members of AMTA. Instrumentation involved a researcher-designed Background Questionnaire as well as the Barriers to Research Utilization Scale (BARRIERS; Funk, Champagne, Wiese, & Tornquist, 1991), a tool designed to assess perceived barriers to incorporating research into practice. Of the 3,194 survey invitations distributed, 974 AMTA members replied (a response rate of 30%). Regarding research-related activities, descriptive findings indicate that journal reading is the most frequently reported research-related activity while conducting research is the least frequently reported activity. Results from the BARRIERS Scale indicated that Organizational and Communication factors are perceived as interfering most prominently with the ability to utilize research in clinical practice. Findings suggest that research-related activity and perceived barriers vary as a function of educational attainment, work setting, and occupational role. The author discusses these differential findings in detail, suggests supportive mechanisms to encourage increased research activity and utilization, and offers recommendations for further analysis of the

  1. Conducting Original Research at the High School Level--the Students' Perspective.

    ERIC Educational Resources Information Center

    Scott, Marcus; VanNoord, Greg

    1996-01-01

    High school students discuss the process of conducting original scientific research in a high school biology course, including developing an idea, obtaining financial support, collecting data, and presenting findings. (MKR)

  2. Educational Research: Planning, Conducting, and Evaluating Quantitative and Qualitative Research, Enhanced Pearson eText with Loose-Leaf Version--Access Card Package. Fifth Edition

    ERIC Educational Resources Information Center

    Creswell, John W.

    2015-01-01

    "Educational Research: Planning, Conducting, and Evaluating Quantitative and Qualitative Research" offers a truly balanced, inclusive, and integrated overview of the processes involved in educational research. This text first examines the general steps in the research process and then details the procedures for conducting specific types…

  3. Embedding Responsible Conduct in Learning and Research into an Australian Undergraduate Curriculum

    ERIC Educational Resources Information Center

    Fernandes, Lynette B.

    2017-01-01

    Responsible conduct in learning and research (RCLR) was progressively introduced into the pharmacology curriculum for undergraduate science students at The University of Western Australia. In the second year of this undergraduate curriculum, a lecture introduces students to issues such as the use of animals in teaching and responsible conduct of…

  4. 42 CFR 51.31 - Conduct of protection and advocacy activities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Conduct of protection and advocacy activities. 51.31 Section 51.31 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS... shall establish policies and procedures to guide and coordinate advocacy activities. The P&A system...

  5. Post-market clinical research conducted by medical device manufacturers: a cross-sectional survey.

    PubMed

    Ross, Joseph S; Blount, Katrina L; Ritchie, Jessica D; Hodshon, Beth; Krumholz, Harlan M

    2015-01-01

    In the US, once a medical device is made available for use, several requirements have been established by the US Food and Drug Administration (FDA) to ensure ongoing post-market surveillance of device safety and effectiveness. Our objective was to determine how commonly medical device manufacturers initiate post-market clinical studies or augment FDA post-market surveillance requirements for higher-risk devices that are most often approved via the FDA's pre-market approval (PMA) pathway. We conducted a cross-sectional survey of 47 manufacturers with operations in California, Minnesota, and Massachusetts who market devices approved via the PMA pathway. Among 22 respondents (response rate =47%), nearly all self-reported conducting post-market clinical research studies, commonly between 1 and 5; only 1 respondent reported never conducting post-market clinical research studies. While manufacturers most often engaged in these studies to satisfy FDA requirements, other reasons were reported, including performance monitoring and surveillance and market acceptance initiatives. Risks of conducting and not conducting post-market clinical research studies were described through open-ended response to questions. Medical device manufacturers commonly initiate post-market clinical studies at the request of the FDA. Clinical data from these studies should be integrated into national post-market surveillance initiatives.

  6. Post-market clinical research conducted by medical device manufacturers: a cross-sectional survey

    PubMed Central

    Ross, Joseph S; Blount, Katrina L; Ritchie, Jessica D; Hodshon, Beth; Krumholz, Harlan M

    2015-01-01

    Background In the US, once a medical device is made available for use, several requirements have been established by the US Food and Drug Administration (FDA) to ensure ongoing post-market surveillance of device safety and effectiveness. Our objective was to determine how commonly medical device manufacturers initiate post-market clinical studies or augment FDA post-market surveillance requirements for higher-risk devices that are most often approved via the FDA’s pre-market approval (PMA) pathway. Methods and results We conducted a cross-sectional survey of 47 manufacturers with operations in California, Minnesota, and Massachusetts who market devices approved via the PMA pathway. Among 22 respondents (response rate =47%), nearly all self-reported conducting post-market clinical research studies, commonly between 1 and 5; only 1 respondent reported never conducting post-market clinical research studies. While manufacturers most often engaged in these studies to satisfy FDA requirements, other reasons were reported, including performance monitoring and surveillance and market acceptance initiatives. Risks of conducting and not conducting post-market clinical research studies were described through open-ended response to questions. Conclusion Medical device manufacturers commonly initiate post-market clinical studies at the request of the FDA. Clinical data from these studies should be integrated into national post-market surveillance initiatives. PMID:26060416

  7. Extracurricular research activities among senior medical students in Kuwait: experiences, attitudes, and barriers.

    PubMed

    Al-Halabi, Becher; Marwan, Yousef; Hasan, Mohammad; Alkhadhari, Sulaiman

    2014-01-01

    Research is the foundation of scientific advancement and improvement in quality of health care, which ensures the good health of the community. The aim of this study is to explore experiences, attitudes, and barriers of medical students in Kuwait University (KU) in regards to extracurricular research. A questionnaire about extracurricular research activities (ie, any research activity that is not part of the required undergraduate curriculum, such as publishing a paper, research elective, etc) was distributed to 175 senior medical students (years 6 and 7). Descriptive and chi-square analyses were used to analyze the responses, considering a P-value of <0.05 as the cut-off level for significance. The main outcome was defined as taking part in any of the extracurricular research activities. Of the 150 participants (response rate = 85.7%), 26 (17.3%), 68 (45.3%), 52 (34.7%), and 17 (11.3%) had published their required medical school research, presented abstracts in conferences, conducted extracurricular research, and completed a research elective/course, respectively; 99 (66.0%) took part in any of these activities. Participants who read medical journals regularly (81; 54%) reported higher participation in extracurricular research activities than those who did not read journals (P=0.003). Improving the availability of mentors for students' extracurricular research was ranked by the participants as the most important factor to improve their participation in extracurricular research (4.05/5.00). Despite the lack of adequate support, extracurricular research activities among medical students of KU were comparable to students from other countries. Barriers for these activities should be addressed by KU medical educators in order to enhance research activities among the students.

  8. Extracurricular research activities among senior medical students in Kuwait: experiences, attitudes, and barriers

    PubMed Central

    Al-Halabi, Becher; Marwan, Yousef; Hasan, Mohammad; Alkhadhari, Sulaiman

    2014-01-01

    Background Research is the foundation of scientific advancement and improvement in quality of health care, which ensures the good health of the community. The aim of this study is to explore experiences, attitudes, and barriers of medical students in Kuwait University (KU) in regards to extracurricular research. Methods A questionnaire about extracurricular research activities (ie, any research activity that is not part of the required undergraduate curriculum, such as publishing a paper, research elective, etc) was distributed to 175 senior medical students (years 6 and 7). Descriptive and chi-square analyses were used to analyze the responses, considering a P-value of <0.05 as the cut-off level for significance. The main outcome was defined as taking part in any of the extracurricular research activities. Results Of the 150 participants (response rate = 85.7%), 26 (17.3%), 68 (45.3%), 52 (34.7%), and 17 (11.3%) had published their required medical school research, presented abstracts in conferences, conducted extracurricular research, and completed a research elective/course, respectively; 99 (66.0%) took part in any of these activities. Participants who read medical journals regularly (81; 54%) reported higher participation in extracurricular research activities than those who did not read journals (P=0.003). Improving the availability of mentors for students’ extracurricular research was ranked by the participants as the most important factor to improve their participation in extracurricular research (4.05/5.00). Conclusion Despite the lack of adequate support, extracurricular research activities among medical students of KU were comparable to students from other countries. Barriers for these activities should be addressed by KU medical educators in order to enhance research activities among the students. PMID:24812535

  9. 14 CFR § 1275.105 - Conduct of the OIG investigation of research misconduct.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... research misconduct. § 1275.105 Section § 1275.105 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275.105 Conduct of the OIG investigation of research misconduct. (a) The OIG shall make every reasonable effort to complete a NASA research misconduct investigation and issue...

  10. Time use differences in activity participation among children 4-5 years old with and without the risk of developing conduct problems.

    PubMed

    Yu, Mong-Lin; Ziviani, Jenny; Baxter, Janeen; Haynes, Michele

    2012-01-01

    Conduct problems in childhood are associated with the way in which children engage in daily activities. Research, to date, on conduct problems in relation to time use has primarily focused on school aged children and their participation in discrete activities such as watching TV and sport. The purpose of the present study is to determine if children at risk of developing conduct problems have different activity patterns compared to those not at risk. Specifically aspects of time use which concern involvement in activities that provide physical exertion, structure, rest and social engagement were examined. Data for this investigation were drawn from the Longitudinal Study of Australian Children (Wave 1) and focused on 4936 children aged 4-5 years. Findings indicate that children at risk of developing conduct problems spend significantly more time in: physical activities such as "riding a bike", and "in the company of adults only" than children not at risk of developing conduct problems but less time "with peers under adult supervision". Gender differences were also found in the same activities with boys participating in more "bike riding" and activities "without peers under adult supervision" than girls. Young children generally participated in more physical activities and spend more time "with peers while supervised by adults" on weekend days, and more time in "structured activities" and "in the company of adults only" on weekdays. These findings are discussed in respect of the potentially risky nature of physical activity choice and the contribution of adult supervision in the context of peer group participation for children at risk of developing conduct problems. Copyright © 2011 Elsevier Ltd. All rights reserved.

  11. A right to confidentiality or a duty to disclose? Ethical guidance for conducting prevention research with children and adolescents.

    PubMed

    Hiriscau, Ioana E; Stingelin-Giles, Nicola; Stadler, Christina; Schmeck, Klaus; Reiter-Theil, Stella

    2014-06-01

    Conducting prevention research with children and adolescents raises ethical challenges especially regarding confidentiality. Research with children and adolescents often applies methodologies which aims at the disclosure of sensitive information about practices that impact on adolescent mental and physical health such as sexual activity, smoking, alcohol consumption, illegal drug use, self-damaging and suicidal behaviour (ideation and attempts). The scope of the article is to review normative documents that cover topics relevant for confidentiality when conducting research with children and adolescents. A systematic literature search in MEDLINE was performed to identify relevant international and European guidelines and codes of ethics that cover health, behavioural and social science research. Additionally, the European Research Ethics website was consulted for double check. However, none of the documents aimed at biomedical, behavioural or social research offers concrete support in resolving practical research ethics problems regarding confidentiality. The codes show a lack of clarity in any circumstances in which the researcher might have an obligation to breach confidentiality by disclosing sensitive information. Only little information is given on what kind of disclosed information, if disclosed, might justify breaching confidentiality. The findings prove a need for normative documents to address the ethical questions regarding confidentiality arising in research practice explicitly and specifically. Moreover, further forms of ethical guidance should be developed to support ethical research with children and adolescents.

  12. 26 CFR 1.355-3 - Active conduct of a trade or business.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 26 Internal Revenue 4 2013-04-01 2013-04-01 false Active conduct of a trade or business. 1.355-3 Section 1.355-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Effects on Shareholders and Security Holders § 1.355-3 Active conduct of a trade or business. (a) Genera...

  13. 26 CFR 1.355-3 - Active conduct of a trade or business.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 26 Internal Revenue 4 2012-04-01 2012-04-01 false Active conduct of a trade or business. 1.355-3 Section 1.355-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (Continued) Effects on Shareholders and Security Holders § 1.355-3 Active conduct of a trade or business. (a) Genera...

  14. Single-molecule conductance studies of photo-active and photochromic molecules

    NASA Astrophysics Data System (ADS)

    Tam, E. S.; Parks, J. J.; Santiago-Berrios, M. B.; Zhong, Y.-W.; Abruna, H. D.; Ralph, D. C.

    2010-03-01

    We perform statistical measurements of single molecule conductance in repeatedly-formed metal-molecule-metal junctions at room temperature. Our results on diaminoalkanes are consistent with those reported by the Venkataraman group. We focus on photo-active and photochromic molecules, including a series of transition-metal complexes with different metal centers and endgroups. We compare the trend in conductance across the family of complexes with that expected from electrochemical measurements. We will also report initial results on the voltage dependence of single-molecule conductances and the effects of optical excitations.

  15. Considering Culturally Relevant Practices and Knowledge-Sharing When Creating an Activity-Promoting Community Research Agenda

    ERIC Educational Resources Information Center

    Coppola, Angela M.; McHugh, Tara-Leigh F.

    2018-01-01

    The purpose of the article is to discuss and reflect upon a process of building relationships and conducting community consultations to co-create a relevant community-based participatory research agenda exploring Indigenous youth activity-promoting programming. Four consultations were conducted with approximately 30 community members in Edmonton,…

  16. The Research and Training Activities for the Joint Institute for Aeronautics and Acoustics

    NASA Technical Reports Server (NTRS)

    Cantwell, Brian

    1997-01-01

    This proposal requests continued support for the program of activities to be undertaken by the Ames-Stanford Joint Institute for Aeronautics and Acoustics during the one-year period October 1, 1997 to September 30, 1998. The emphasis in this program is on training and research in experimental and computational methods with application to aerodynamics, acoustics and the important interactions between them. The program comprises activities in active flow control, Large Eddy Simulation of jet noise, flap aerodynamics and acoustics, high lift modeling studies and luminescent paint applications. During the proposed period there will be a continued emphasis on the interaction between NASA Ames, Stanford University and Industry, particularly in connection with the noise and high lift activities. The program will be conducted within the general framework of the Memorandum of Understanding (1976) establishing the Institute, as updated in 1993. As outlined in the agreement, the purposes of the Institute include the following: (1) To conduct basic and applied research; (2) to promote joint endeavors between Center scientists and those in the academic community; (3) to provide training to graduate students in specialized areas of aeronautics and acoustics through participation in the research programs of the Institute; (4) to provide opportunities for Post-Doctoral Fellows to collaborate in research programs of the Institute; and (5) to disseminate information about important aeronautical topics and to enable scientists and engineers of the Center to stay abreast of new advances through symposia, seminars and publications.

  17. The Research and Training Activities for the Joint Institute for Aeronautics and Acoustics

    NASA Technical Reports Server (NTRS)

    Cantwell, Brian

    1996-01-01

    This proposal requests continued support for the program of activities to be undertaken by the Ames-Stanford Joint Institute for Aeronautics and Acoustics during the one-year period October 1, 1996 to September 30, 1997. The emphasis in this program is on training and research in experimental and computational methods with application to aerodynamics, acoustics and the important interactions between them. The program comprises activities in active flow control, Large Eddy Simulation of jet noise, flap aerodynamics and acoustics, high lift modeling studies and luminescent paint applications. During the proposed period there will be a continued emphasis on the interaction between NASA Ames, Stanford University and Industry, particularly in connection with the noise and high lift activities. The program will be conducted within the general framework of the Memorandum of Understanding (1976) establishing the Institute, as updated in 1993. As outlined in the agreement, the purposes of the institute include the following: To conduct basic and applied research. To promote joint endeavors between Center scientists and those in the academic community To provide training to graduate students in specialized areas of aeronautics and acoustics through participation in the research programs of the Institute. To provide opportunities for Post-Doctoral Fellows to collaborate in research programs of the Institute. To disseminate information about important aeronautical topics and to enable scientists and engineers of the Center to stay abreast of new advances through symposia, seminars and publications.

  18. Interface-Controlled Conductive Fibers for Wearable Strain Sensors and Stretchable Conducting Wires.

    PubMed

    Cao, Zherui; Wang, Ranran; He, Tengyu; Xu, Fangfang; Sun, Jing

    2018-04-25

    As an important subfield of flexible electronics, conductive fibers have been an active area of research. The interfacial interaction between nanostructured conductive materials with elastic substrates plays a vital role in the electromechanical performance of conductive fibers. However, the underlying mechanism has seldom been investigated. Here, we propose a fabricating strategy for a silver nanowire (Ag NW)/polyurethane composite fiber with a sheath-core architecture. The interfacial bonding layer is regulated, and its influence on the performance of conductive fibers is investigated, based on which an interfacial interaction model is proposed. The model underlines the significance of the embedding depth of the Ag NW network. Both supersensitive (gauge factor up to 9557) and ultrastable (negligible conductance degradation below the strain of 150%) conductive fibers are obtained via interface regulating, exhibiting great potential in the applications of wearable sensors and stretchable conducting connections.

  19. Conducting environmental health research in the Arabian Middle East: lessons learned and opportunities.

    PubMed

    Yeatts, Karin B; El-Sadig, Mohamed; Ali, Habiba I; Al-Maskari, Fatma; Campbell, Alan; Ng, Shu Wen; Reeves, Lisa; Chan, Ronna L; Davidson, Christopher A; Funk, William E; Boundy, Maryanne G; Leith, David; Popkin, Barry; Gibson, Jacqueline Macdonald; Rusyn, Ivan; Olshan, Andrew F

    2012-05-01

    The Arabian Gulf nations are undergoing rapid economic development, leading to major shifts in both the traditional lifestyle and the environment. Although the pace of change is brisk, there is a dearth of environmental health research in this region. We describe challenges and successes of conducting an environmental epidemiologic study in the United Arab Emirates (UAE), a Gulf nation in the Middle East, with an inter-disciplinary team that includes in-country academic and government collaborators as well as U.S. academic collaborators. We present several issues, including study and data collection design, exposure assessment, scheduling and time coordination, quality assurance and quality control, and institutional review board protocols. These topics are considered in a cultural context. Benefits of this research included building linkages among multinational, interdisciplinary team members, generating data for local environmental decision making, and developing local epidemiologic research capacity. The Middle Eastern culture of hospitality greatly benefited the project team. Cultural differences impact multiple aspects of epidemiologic research and should be respectfully addressed. Conducting international population-based environmental research poses many challenges; these challenges can be met successfully with careful planning, cultural knowledge, and flexibility. Lessons learned are applicable to interdisciplinary research all over the world. The research conducted will benefit the environmental and public health agencies of the UAE and provide the nation's leadership with country-specific environmental health data that can be used to protect the public's health in a rapidly changing environment.

  20. Conducting Environmental Health Research in the Arabian Middle East: Lessons Learned and Opportunities

    PubMed Central

    El-Sadig, Mohamed; Ali, Habiba I.; Al-Maskari, Fatma; Campbell, Alan; Ng, Shu Wen; Reeves, Lisa; Chan, Ronna L.; Davidson, Christopher A.; Funk, William E.; Boundy, Maryanne G.; Leith, David; Popkin, Barry; Gibson, Jacqueline MacDonald; Rusyn, Ivan; Olshan, Andrew F.

    2012-01-01

    Background: The Arabian Gulf nations are undergoing rapid economic development, leading to major shifts in both the traditional lifestyle and the environment. Although the pace of change is brisk, there is a dearth of environmental health research in this region. Objective: We describe challenges and successes of conducting an environmental epidemiologic study in the United Arab Emirates (UAE), a Gulf nation in the Middle East, with an inter-disciplinary team that includes in-country academic and government collaborators as well as U.S. academic collaborators. Discussion: We present several issues, including study and data collection design, exposure assessment, scheduling and time coordination, quality assurance and quality control, and institutional review board protocols. These topics are considered in a cultural context. Benefits of this research included building linkages among multinational, interdisciplinary team members, generating data for local environmental decision making, and developing local epidemiologic research capacity. The Middle Eastern culture of hospitality greatly benefited the project team. Conclusion: Cultural differences impact multiple aspects of epidemiologic research and should be respectfully addressed. Conducting international population-based environmental research poses many challenges; these challenges can be met successfully with careful planning, cultural knowledge, and flexibility. Lessons learned are applicable to interdisciplinary research all over the world. The research conducted will benefit the environmental and public health agencies of the UAE and provide the nation’s leadership with country-specific environmental health data that can be used to protect the public’s health in a rapidly changing environment. PMID:22356946

  1. Danish research-active clinical nurses overcome barriers in research utilization.

    PubMed

    Adamsen, Lis; Larsen, Kristian; Bjerregaard, Lene; Madsen, Jan K

    2003-03-01

    The aim of this study was to examine whether there was a difference between clinical nurses who were research-active, and clinical nurses who were nonresearch-active in utilization of research. A further aim was to identify the most significant barriers faced by a group of Danish clinical nurses in their use of research. Discrepancy between the improved quality of research results and the lack of implementing them was the starting point for a series of studies which showed the types of barriers clinical nurses found especially cumbersome when applying the research results of other researchers. This study investigates whether the clinical nurses' own engagement in research had any impact on their perception of research utilization. The study had an exploratory and descriptive design. Seventy-nine Danish clinical nurses participated and semi-structured interviewing was used as the research method. There was a statistically significant difference between the research-active and nonresearch-active nurses on various variables. The study showed that, to a larger extent, research-active nurses used evidence-based knowledge and were generally more internationally orientated. Furthermore, two important barriers for research utilization were identified by all 79 clinical nurses included in the study, i.e. 90% of the nurses explained that the quantity of research results was overwhelming, and 75% of them found that they were unable to evaluate the quality of the research. Clinical nurses, who were research-active themselves, experienced more success in overcoming some of the barriers, which existed in applying research to practice. The research potential found amongst clinical nurses in Denmark needed to be further supported through training and guidance in research methodology, establishing introductory stipends and part-time research positions. By doing so, some of the barriers affecting research utilization and the so-called theory-practice gap might be reduced. Further

  2. Conducting Action Research in a Practicum: A Student Teacher's Perspective

    ERIC Educational Resources Information Center

    Kasula, Alex

    2015-01-01

    This article looks at my reflection as a teacher during a master's degree practicum for a Second Language Studies Program. This particular practicum differs from the other common student teacher-training courses found in master's programs as it incorporated a teacher-training session on conducting action research (AR) in the classroom, a practice…

  3. A scoping review of reporting 'Ethical Research Practices' in research conducted among refugees and war-affected populations in the Arab world.

    PubMed

    Makhoul, Jihad; Chehab, Rana F; Shaito, Zahraa; Sibai, Abla M

    2018-05-15

    Ethical research conduct is a cornerstone of research practice particularly when research participants include vulnerable populations. This study mapped the extent of reporting ethical research practices in studies conducted among refugees and war-affected populations in the Arab World, and assessed variations by time, country of study, and study characteristics. An electronic search of eight databases resulted in 5668 unique records published between 2000 and 2013. Scoping review yielded 164 eligible articles for analyses. Ethical research practices, including obtaining institutional approval, access to the community/research site, and informed consent/assent from the research participants, were reported in 48.2, 54.9, and 53.7% of the publications, respectively. Institutional approval was significantly more likely to be reported when the research was biomedical in nature compared to public health and social (91.7% vs. 54.4 and 32.4%), when the study employed quantitative compared to qualitative or mixed methodologies (61.7% vs. 26.8 and 42.9%), and when the journal required a statement on ethical declarations (57.4% vs. 27.1%). Institutional approval was least likely to be reported in papers that were sole-authored (9.5%), when these did not mention a funding source (29.6%), or when published in national journals (0%). Similar results were obtained for access to the community site and for seeking informed consent/assent from study participants. The responsibility of inadequacies in adherence to ethical research conduct in crisis settings is born by a multitude of stakeholders including funding agencies, institutional research boards, researchers and international relief organizations involved in research, as well as journal editors, all of whom need to play a more proactive role for enhancing the practice of ethical research conduct in conflict settings.

  4. Prison health service directors' views on research priorities and organizational issues in conducting research in prison: outcomes of a national deliberative roundtable.

    PubMed

    Simpson, Paul Leslie; Guthrie, Jill; Butler, Tony

    2017-06-12

    Purpose Given that prisoners have significant health needs across most areas, the paucity of prisoner health research, and the difficulties involved in the conduct of research in this setting, there is a need to develop research priorities that align with key stakeholder groups. One such group are those responsible for health service provision in prisons - prison health service directors. The paper aims to discuss these issues. Design/methodology/approach Prison health service directors in each Australian state and territory were invited to participate in a national (deliberative) roundtable where the consensus building nominal group technique was utilized. This involved the identification of research priorities and organizational issues in conducting research with prisoners, and ranking research priorities. A thematic analysis was conducted on organizational issues. Findings In total, 13 participants attended the roundtable. Participants identified 28 research priorities and 12 organizational issues. Top ranked research priorities were mental health, cognitive and intellectual disability, post-release health maintenance, ageing prisoners, chronic health conditions and Aboriginal and Torres Strait Islander health. Themes identified from the organizational issues included prisoner access to research participation, health and research literacy of custodial staff, and institutional protectionism in response to research that may discover negative information about the custodial setting. Research limitations/implications These findings should inform future efforts to improve research infrastructures to undertake research to improve the health of people in Australian prisons, and help to align researchers' efforts with those of a key organizational stakeholder. Originality/value This is the first paper to determine the research priorities and organizational issues in conducting research in prisons of prison health service directors.

  5. Local vs. volume conductance activity of field potentials in the human subthalamic nucleus

    PubMed Central

    Marmor, Odeya; Valsky, Dan; Joshua, Mati; Bick, Atira S; Arkadir, David; Tamir, Idit; Bergman, Hagai; Israel, Zvi

    2017-01-01

    Subthalamic nucleus field potentials have attracted growing research and clinical interest over the last few decades. However, it is unclear whether subthalamic field potentials represent locally generated neuronal subthreshold activity or volume conductance of the organized neuronal activity generated in the cortex. This study aimed at understanding of the physiological origin of subthalamic field potentials and determining the most accurate method for recording them. We compared different methods of recordings in the human subthalamic nucleus: spikes (300–9,000 Hz) and field potentials (3–100 Hz) recorded by monopolar micro- and macroelectrodes, as well as by differential-bipolar macroelectrodes. The recordings were done outside and inside the subthalamic nucleus during electrophysiological navigation for deep brain stimulation procedures (150 electrode trajectories) in 41 Parkinson’s disease patients. We modeled the signal and estimated the contribution of nearby/independent vs. remote/common activity in each recording configuration and area. Monopolar micro- and macroelectrode recordings detect field potentials that are considerably affected by common (probably cortical) activity. However, bipolar macroelectrode recordings inside the subthalamic nucleus can detect locally generated potentials. These results are confirmed by high correspondence between the model predictions and actual correlation of neuronal activity recorded by electrode pairs. Differential bipolar macroelectrode subthalamic field potentials can overcome volume conductance effects and reflect locally generated neuronal activity. Bipolar macroelectrode local field potential recordings might be used as a biological marker of normal and pathological brain functions for future electrophysiological studies and navigation systems as well as for closed-loop deep brain stimulation paradigms. NEW & NOTEWORTHY Our results integrate a new method for human subthalamic recordings with a development of

  6. Teaching and Assessing the Responsible Conduct of Research: A Delphi Consensus Panel Report

    ERIC Educational Resources Information Center

    DuBois, James M.; Dueker, Jeffrey M.

    2009-01-01

    In an effort to foster research integrity, the National Institutes of Health and the National Science Foundation mandate education of all trainees in the responsible conduct of research (RCR). Nevertheless, recent studies suggest that rates of questionable research practices and scientific misconduct are both high and considerably underreported.…

  7. Art Therapists and Research: A Survey Conducted by the Potomac Art Therapy Association.

    ERIC Educational Resources Information Center

    Betts, Donna J.; Laloge, Laura

    2000-01-01

    The Potomac Art Therapy Association (PATA) conducted a survey of its members' involvement in and attitudes toward research. Two factors were found to contribute to art therapists' hesitancy to pursue research: (1) a lack of training; and (2) statistics and mathematics. Discusses PATA's initiatives to promote research. (Author/JDM)

  8. Stratton Sagebrush Hydrology Study Area: An annotated bibliography of research conducted 1968-1990

    USGS Publications Warehouse

    Burgess, Leah M.; Schoenecker, Kathryn A.

    2004-01-01

    This annotated bibliography provides an overview of research projects conducted on the Stratton Sagebrush Hydrology Study Area (Stratton) since its designation as such in 1967. Sources include the Rocky Mountain Forest and Range Experiment Station records storage room, Laramie, Wyoming, the USGS and USFS online reference libraries, and scientific journal databases at the University of Wyoming and Colorado State University. This annotated bibliography summarizes publications from research conducted at Stratton during the prime of its tenure as a research lab from 1968 to 1990. In addition, an appendix is included that catalogues all data on file at the Rocky Mountain Forest and Range Experiment Station in Laramie, Wyoming. Each file folder was searched and its contents recorded here for the researcher seeking original data sets, charts, photographs and records.

  9. Embedding responsible conduct in learning and research into an Australian undergraduate curriculum.

    PubMed

    Fernandes, Lynette B

    2017-01-02

    Responsible conduct in learning and research (RCLR) was progressively introduced into the pharmacology curriculum for undergraduate science students at The University of Western Australia. In the second year of this undergraduate curriculum, a lecture introduces students to issues such as the use of animals in teaching and responsible conduct of research. Third year student groups deliver presentations on topics including scientific integrity and the use of human subjects in research. Academic and research staff attending these presentations provide feedback and participate in discussions. Students enrolled in an optional capstone Honours year complete an online course on the responsible conduct of research and participate in an interactive movie. Once RCLR became established in the curriculum, a survey of Likert-scaled and open-ended questions examined student and staff perceptions. Data were expressed as Approval (% of responses represented by Strongly Agree and Agree). RCLR was found to be relevant to the study of pharmacology (69-100% Approval), important for one's future career (62-100% Approval), and stimulated further interest in this area (32-75% Approval). Free entry comments demonstrated the value of RCLR and constructive suggestions for improvement have now been incorporated. RCLR modules were found to be a valuable addition to the pharmacology undergraduate curriculum. This approach may be used to incorporate ethics into any science undergraduate curriculum, with the use of discipline-specific topics. © 2016 by The International Union of Biochemistry and Molecular Biology, 45(1):53-59, 2017. © 2016 The International Union of Biochemistry and Molecular Biology.

  10. 12 CFR 208.72 - What activities may a financial subsidiary conduct?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... insurance company investment activity permitted for financial holding companies by section 4(k)(4)(H) or (I... 12 Banks and Banking 2 2011-01-01 2011-01-01 false What activities may a financial subsidiary...) Financial Subsidiaries of State Member Banks § 208.72 What activities may a financial subsidiary conduct? (a...

  11. 12 CFR 208.72 - What activities may a financial subsidiary conduct?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... insurance company investment activity permitted for financial holding companies by section 4(k)(4)(H) or (I... 12 Banks and Banking 2 2010-01-01 2010-01-01 false What activities may a financial subsidiary...) Financial Subsidiaries of State Member Banks § 208.72 What activities may a financial subsidiary conduct? (a...

  12. Guidelines for Conducting and Reporting Mixed Research in the Field of Counseling and beyond

    ERIC Educational Resources Information Center

    Leech, Nancy L.; Onwuegbuzie, Anthony J.

    2010-01-01

    This article provides guidelines for conducting, reporting, and evaluating mixed research studies in 3 sections: research formulation, research planning, and research implementation. To date, no such guidelines are available. Detailed descriptions of each subsection are included. The authors hope that these standards assist researchers from the…

  13. A Review of Recent RLV Research Activities in Japan

    NASA Astrophysics Data System (ADS)

    Sasaki, Makoto; Watanabe, Atsutaro

    2004-02-01

    Researches on reusable launch vehicle (RLV) in Japan have been conducted mainly by the three space agencies: the National Space Development Agency of Japan (NASDA), the National Aerospace Laboratory of Japan (NAL) and the Institute of Space and Astronautical Science (ISAS). HOPE-X program by NASDA/NAL, spaceplane/scramjet related researches by NAL, and development studies of ATREX engine and small reusable vehicle testing (RVT) by ISAS are such major activities. After the consecutive launch failures of NASDA's H-II and ISAS's M-V rockets in 1999-2000, it was concluded that more intensive efforts should be concentrated on the reliability improvement of those major expendable vehicles and that RLV related researches should be promoted to establish fundamental technologies essential to future RLV. In past two years, NASDA succeeded in five consecutive launches of new H-IIA, and ISAS successfully resumed the launch of M-V. As for RLV researches, considerable progress has been achieved in the high speed flight demonstration (HSFD) tests of HOPE-X program, scramjet tests of Mach 4 to 8 by NAL, and ATREX engine and small RVT tests by ISAS. The current three space agencies will be merged into one in October 2003 to establish a new organization named Japan Aerospace Exploration Agency (JAXA). It is expected that the above research activities will be also merged to promote a higher-level research program on RLV.

  14. Transmission research activities at NASA Lewis Research Center

    NASA Technical Reports Server (NTRS)

    Lewicki, D. G.

    1990-01-01

    A joint research program, to advance the technology of rotorcraft transmissions, consists of analytical and experimental efforts to achieve the overall goals of reducing transmission weight and noise, while increasing life and reliability. Recent activities in the areas of transmission and related component research are highlighted. Current areas include specific technologies in support of military rotary wing aviation, gearing technology, transmission noise reduction studies, a recent interest in gearbox diagnostics, and advanced transmission system studies. Results of recent activities are presented along with near term research plans.

  15. Factors that Motivate Business Faculty to Conduct Research: An Expectancy Theory Analysis

    ERIC Educational Resources Information Center

    Chen, Yining; Gupta, Ashok; Hoshower, Leon

    2006-01-01

    In this study, the authors used expectancy theory to examine key factors that motivate business faculty to conduct research. The survey results, from 320 faculty members at 10 business schools, showed that faculty members who assign higher importance ratings to both the extrinsic and the intrinsic rewards of research exhibit higher research…

  16. Conducting Action Research in Kenyan Primary Schools: A Narrative of Lived Experiences

    ERIC Educational Resources Information Center

    Otienoh, Ruth

    2015-01-01

    This paper is a narrative of my personal experiences of conducting action research in Kenyan primary schools. It highlights the opportunities, successes, challenges and dilemmas I encountered during the process: from the school hunting period, to the carrying out of the actual research in two schools, with four teachers. This study reveals that…

  17. Will Undergraduate Students Play Games to Learn How to Conduct Library Research?

    ERIC Educational Resources Information Center

    Markey, Karen; Swanson, Fritz; Jenkins, Andrea; Jennings, Brian; St. Jean, Beth; Rosenberg, Victor; Yao, Xingxing; Frost, Robert

    2009-01-01

    This exploratory study examines whether undergraduate students will play games to learn how to conduct library research. Results indicate that students will play games that are an integral component of the course curriculum and enable them to accomplish overall course goals at the same time they learn about library research. (Contains 1 table.)

  18. Sugar beet activities of the USDA-ARS East Lansing conducted in cooperation with Saginaw Research & Extension Center during 2013 (including Project 905)

    USDA-ARS?s Scientific Manuscript database

    Evaluation and rating plots were planted at the Saginaw Valley Research & Extension Center (SVREC) in Frankenmuth, MI in 2013 that focused on Cercospora leaf spot and Rhizoctonia seedling disease performance of a wide range of Beta vulgaris materials. Leaf spot trials were conducted in conjunction w...

  19. 30 CFR 285.614 - When may I begin conducting activities under my approved SAP?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... approved SAP? 285.614 Section 285.614 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... Plans and Information Requirements Activities Under An Approved Sap § 285.614 When may I begin conducting activities under my approved SAP? (a) You may begin conducting the activities approved in your SAP...

  20. Collaboration as Community: Outcomes of Conducting Research on One's Colleagues.

    ERIC Educational Resources Information Center

    Slater, Marsha S.

    A series of interviews carried out over a 6-month period investigated: (1) why and how five New York City high school teachers used writing-to-learn across the curriculum, and, (2) the outcome of conducting research on one's own colleagues. Subjects were a math teacher, a physics teacher, and a career education teacher from a high school for…

  1. 21 CFR 312.87 - Active monitoring of conduct and evaluation of clinical trials.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Active monitoring of conduct and evaluation of clinical trials. 312.87 Section 312.87 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH... to Treat Life-threatening and Severely-debilitating Illnesses § 312.87 Active monitoring of conduct...

  2. 21 CFR 312.87 - Active monitoring of conduct and evaluation of clinical trials.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Active monitoring of conduct and evaluation of clinical trials. 312.87 Section 312.87 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH... to Treat Life-threatening and Severely-debilitating Illnesses § 312.87 Active monitoring of conduct...

  3. 21 CFR 312.87 - Active monitoring of conduct and evaluation of clinical trials.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Active monitoring of conduct and evaluation of clinical trials. 312.87 Section 312.87 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH... to Treat Life-threatening and Severely-debilitating Illnesses § 312.87 Active monitoring of conduct...

  4. 21 CFR 312.87 - Active monitoring of conduct and evaluation of clinical trials.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Active monitoring of conduct and evaluation of clinical trials. 312.87 Section 312.87 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH... to Treat Life-threatening and Severely-debilitating Illnesses § 312.87 Active monitoring of conduct...

  5. 78 FR 47282 - Takes of Marine Mammals Incidental to Specified Activities; Navy Research, Development, Test and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-05

    ... Director. Post-mission surveys will be conducted from the surface vessel(s) and aircraft used for pre-test... post-test events. Systematic monitoring of the affected area for marine mammals will be conducted prior... Marine Mammals Incidental to Specified Activities; Navy Research, Development, Test and Evaluation...

  6. Geoscience and Political Instability: Policies and Philosophies for Conducting Research in the Political Terra Infirma

    NASA Astrophysics Data System (ADS)

    Kelmelis, J.

    2006-12-01

    Earth scientists must conduct their work on, in or above the Earth, wherever the scientific questions can best be answered. This can put the scientist in harms way. Although the science itself can be policy or politics neutral, it may not be viewed that way in some locations. Still, the geosciences are a foundation of national security in the strictest statist sense as well as in the evolving concept of security, which incorporates the many sectors of society. On one extreme of this multi axis framework they inform military operations and on another, sustainable development cannot be conducted without them. Some geoscience issues are truly global and none respect borders unless the borders are defined by the earth itself. Yet, they are problematic in they require field work, which sometimes must logically cross political rift zones into erupting political conflicts. Describing the landscape of conflict is difficult. It can change rapidly due to internal or external variables. It can be redefined by the by the viewer as the political landscape shifts under his or her feet. As a result, there is no single policy for conducting scientific research in areas of political conflict, but a collection of policies, some fairly constant and some changing. Issues such as bi- and multi-lateral relations, legal aspects of scientific and technological exchange, and potential health and safety of the scientists must be considered along with the type of scientific work to be conducted. In fact, the organization from which the scientist originates is a concern in some areas as well. In this presentation I discuss several types of conflict, the United States' Country Level Foreign Assistance Framework, the objectives of U.S. foreign policy strategy, transformational diplomacy, and the importance of earth and natural sciences to them. I consider several cases involving different nations, different types and levels of conflict, and different scientific activities. I also ask the earth

  7. Barriers and Solutions to Conducting Large International, Interdisciplinary Research Projects

    NASA Astrophysics Data System (ADS)

    Pischke, Erin C.; Knowlton, Jessie L.; Phifer, Colin C.; Gutierrez Lopez, Jose; Propato, Tamara S.; Eastmond, Amarella; de Souza, Tatiana Martins; Kuhlberg, Mark; Picasso Risso, Valentin; Veron, Santiago R.; Garcia, Carlos; Chiappe, Marta; Halvorsen, Kathleen E.

    2017-12-01

    Global environmental problems such as climate change are not bounded by national borders or scientific disciplines, and therefore require international, interdisciplinary teamwork to develop understandings of their causes and solutions. Interdisciplinary scientific work is difficult enough, but these challenges are often magnified when teams also work across national boundaries. The literature on the challenges of interdisciplinary research is extensive. However, research on international, interdisciplinary teams is nearly non-existent. Our objective is to fill this gap by reporting on results from a study of a large interdisciplinary, international National Science Foundation Partnerships for International Research and Education (NSF-PIRE) research project across the Americas. We administered a structured questionnaire to team members about challenges they faced while working together across disciplines and outside of their home countries in Argentina, Brazil, and Mexico. Analysis of the responses indicated five major types of barriers to conducting interdisciplinary, international research: integration, language, fieldwork logistics, personnel and relationships, and time commitment. We discuss the causes and recommended solutions to the most common barriers. Our findings can help other interdisciplinary, international research teams anticipate challenges, and develop effective solutions to minimize the negative impacts of these barriers to their research.

  8. Barriers and Solutions to Conducting Large International, Interdisciplinary Research Projects.

    PubMed

    Pischke, Erin C; Knowlton, Jessie L; Phifer, Colin C; Gutierrez Lopez, Jose; Propato, Tamara S; Eastmond, Amarella; de Souza, Tatiana Martins; Kuhlberg, Mark; Picasso Risso, Valentin; Veron, Santiago R; Garcia, Carlos; Chiappe, Marta; Halvorsen, Kathleen E

    2017-12-01

    Global environmental problems such as climate change are not bounded by national borders or scientific disciplines, and therefore require international, interdisciplinary teamwork to develop understandings of their causes and solutions. Interdisciplinary scientific work is difficult enough, but these challenges are often magnified when teams also work across national boundaries. The literature on the challenges of interdisciplinary research is extensive. However, research on international, interdisciplinary teams is nearly non-existent. Our objective is to fill this gap by reporting on results from a study of a large interdisciplinary, international National Science Foundation Partnerships for International Research and Education (NSF-PIRE) research project across the Americas. We administered a structured questionnaire to team members about challenges they faced while working together across disciplines and outside of their home countries in Argentina, Brazil, and Mexico. Analysis of the responses indicated five major types of barriers to conducting interdisciplinary, international research: integration, language, fieldwork logistics, personnel and relationships, and time commitment. We discuss the causes and recommended solutions to the most common barriers. Our findings can help other interdisciplinary, international research teams anticipate challenges, and develop effective solutions to minimize the negative impacts of these barriers to their research.

  9. Conducting longitudinal, process-oriented research with conflict-affected youth: Solving the inevitable challenges.

    PubMed

    Dubow, Eric F; Aber, J Lawrence; Betancourt, Theresa S; Cummings, E Mark; Huesmann, L Rowell

    2017-02-01

    The reader might get the impression that the four projects described in this Special Section proceeded in a systematic and predictable way. Of course, those of us engaged in each research project encountered pitfalls and challenges along the way. A main goal of this Special Section is to provide pathways and encouragement for those who may be interested in advancing high-quality research on this topic. In this paper, we describe a set of practical and ethical challenges that we encountered in conducting our longitudinal, process-oriented, and translational research with conflict-affected youth, and we illustrate how problems can be solved with the goal of maintaining the internal and external validity of the research designs. We are hopeful that by describing the challenges of our work, and how we overcame them, which are seldom treated in this or any other literature on research on child development in high-risk contexts, we can offer a realistic and encouraging picture of conducting methodologically sound research in conflict-affected contexts.

  10. Conducting research in risk communication that is both beneficial for stakeholders and scientists

    NASA Astrophysics Data System (ADS)

    Charrière, Marie; Bogaard, Thom; Junier, Sandra; Malet, Jean-Philippe; Mostert, Erik

    2015-04-01

    One of the key tasks for disaster risk reduction is raising awareness. On way to increase it is through risk communication, including visual risk communication. Previous research showed that visual risk communication linked to natural hazards is mostly evaluated in terms of user's requirements, ability to understand the content, or satisfaction with the diverse components of the tool(s): Its impact on risk awareness is not researched. Most of the risk communication evaluations are performed in a lab-type environments and thus their conclusions might not be fully valid in real life settings. Our approach differs in the sense that we decided to test a real communication effort. However, we did not use an existing one but designed our own. This process was conducted according to collaborative research principles, meaning that we created the communication effort in collaboration with the local stakeholders in order to respect the social environment of the case study. Moreover, our research activity should be beneficial and significant for the community in which we work as well as for science. This contribution will present the process that allowed us to design an exhibition in the Ubaye Valley (France) and the methodology that was developed to measure changes in risk awareness. During a 2-years project, we collaborated with local and regional stakeholders (politicians and technicians). Informal meetings with local stakeholders were organized to determine what they perceived as the needs in term of risk communication and to investigate the potential to develop activities that would benefit both them and us. We were offered the opportunity to design an exhibition for the local public library. We proposed the content and this was adjusted in interaction with the stakeholders. Later local technicians and inhabitants contributed to the content of the exhibition and regional stakeholders helped with the funding of the exhibition. Finally, employees of the public library took

  11. Future Directions for Research on the Development and Prevention of Early Conduct Problems

    ERIC Educational Resources Information Center

    Shaw, Daniel S.

    2013-01-01

    This article describes our state of knowledge regarding the development and prevention of conduct problems in early childhood, then identifies directions that would benefit future basic and applied research. Our understanding about the course and risk factors associated with early-developing conduct problems has been significantly enhanced during…

  12. A Methodology for Conducting Integrative Mixed Methods Research and Data Analyses

    PubMed Central

    Castro, Felipe González; Kellison, Joshua G.; Boyd, Stephen J.; Kopak, Albert

    2011-01-01

    Mixed methods research has gained visibility within the last few years, although limitations persist regarding the scientific caliber of certain mixed methods research designs and methods. The need exists for rigorous mixed methods designs that integrate various data analytic procedures for a seamless transfer of evidence across qualitative and quantitative modalities. Such designs can offer the strength of confirmatory results drawn from quantitative multivariate analyses, along with “deep structure” explanatory descriptions as drawn from qualitative analyses. This article presents evidence generated from over a decade of pilot research in developing an integrative mixed methods methodology. It presents a conceptual framework and methodological and data analytic procedures for conducting mixed methods research studies, and it also presents illustrative examples from the authors' ongoing integrative mixed methods research studies. PMID:22167325

  13. Easier said than done!: methodological challenges with conducting maternal death review research in Malawi.

    PubMed

    Combs Thorsen, Viva; Sundby, Johanne; Meguid, Tarek; Malata, Address

    2014-02-21

    Maternal death auditing is widely used to ascertain in-depth information on the clinical, social, cultural, and other contributing factors that result in a maternal death. As the 2015 deadline for Millennium Development Goal 5 of reducing maternal mortality by three quarters between 1990 and 2015 draws near, this information becomes even more critical for informing intensified maternal mortality reduction strategies. Studies using maternal death audit methodologies are widely available, but few discuss the challenges in their implementation. The purpose of this paper is to discuss the methodological issues that arose while conducting maternal death review research in Lilongwe, Malawi. Critical reflections were based on a recently conducted maternal mortality study in Lilongwe, Malawi in which a facility-based maternal death review approach was used. The five-step maternal mortality surveillance cycle provided the framework for discussion. The steps included: 1) identification of cases, 2) data collection, 3) data analysis, 4) recommendations, and 5) evaluation. Challenges experienced were related to the first three steps of the surveillance cycle. They included: 1) identification of cases: conflicting maternal death numbers, and missing medical charts, 2) data collection: poor record keeping, poor quality of documentation, difficulties in identifying and locating appropriate healthcare workers for interviews, the potential introduction of bias through the use of an interpreter, and difficulties with locating family and community members and recall bias; and 3) data analysis: determining the causes of death and clinical diagnoses. Conducting facility-based maternal death reviews for the purpose of research has several challenges. This paper illustrated that performing such an activity, particularly the data collection phase, was not as easy as conveyed in international guidelines and in published studies. However, these challenges are not insurmountable. If they are

  14. Usability of Mobile Phones in Physical Activity-Rrelated Research: A Systematic Review

    ERIC Educational Resources Information Center

    Monroe, Courtney M.; Thompson, Dixie L.; Bassett, David R., Jr.; Fitzhugh, Eugene C.; Raynor, Hollie A.

    2015-01-01

    Background: The use of mobile phones for physical activity (PA) promotion and assessment represents an attractive research area because this technology is characterized by a widespread reach and dynamic features. Purpose: The purpose of this study was to conduct a systematic review of mobile phone-based approaches for encouraging and assessing PA.…

  15. Nutrition professionals are obligated to follow ethical guidelines when conducting industry-funded research

    USDA-ARS?s Scientific Manuscript database

    The fiscal climate for research reflects the increasing difficulty in obtaining competitive government and foundation funds. Thus, nutrition professionals conducting research may need to work with industry. However, there is a growing concern about real or perceived conflicts of interest and the pot...

  16. Graduate Socialization in the Responsible Conduct of Research: A National Survey on the Research Ethics Training Experiences of Psychology Doctoral Students

    PubMed Central

    Fisher, Celia B.; Fried, Adam L.; Feldman, Lindsay G.

    2013-01-01

    Little is known about the mechanisms by which psychology graduate programs transmit responsible conduct of research (RCR) values. A national sample of 968 current students and recent graduates of mission-diverse doctoral psychology programs, completed a web-based survey on their research ethics challenges, perceptions of RCR mentoring and department climate, their ability to conduct research responsibility, and whether they believed psychology as a discipline promotes scientific integrity. Research experience, mentor RCR instruction and modeling, and department RCR policies predicted student RCR preparedness. Mentor RCR instruction, department RCR policies, and faculty modeling of RCR behaviors predicted confidence in the RCR integrity of the discipline. Implications for training are discussed. PMID:23641128

  17. Survey on astrobiology research and teaching activities within the United kingdom.

    PubMed

    Dartnell, Lewis R; Burchell, Mark J

    2009-10-01

    While astrobiology is apparently growing steadily around the world, in terms of the number of researchers drawn into this interdisciplinary area and teaching courses provided for new students, there have been very few studies conducted to chart this expansion quantitatively. To address this deficiency, the Astrobiology Society of Britain (ASB) conducted a questionnaire survey of universities and research institutions nationwide to ascertain the current extent of astrobiology research and teaching in the UK. The aim was to provide compiled statistics and an information resource for those who seek research groups or courses of study, and to facilitate new interdisciplinary collaborations. The report here summarizes details gathered on 33 UK research groups, which involved 286 researchers (from undergraduate project students to faculty members). The survey indicates that around 880 students are taking university-level courses, with significant elements of astrobiology included, every year in the UK. Data are also presented on the composition of astrobiology students by their original academic field, which show a significant dominance of physics and astronomy students. This survey represents the first published systematic national assessment of astrobiological academic activity and indicates that this emerging field has already achieved a strong degree of penetration into the UK academic community.

  18. Establishing good collaborative research practices in the responsible conduct of research in nursing science.

    PubMed

    Ulrich, Connie M; Wallen, Gwenyth R; Cui, Naixue; Chittams, Jesse; Sweet, Monica; Plemmons, Dena

    2015-01-01

    Team science is advocated to speed the pace of scientific discovery, yet the goals of collaborative practice in nursing science and the responsibilities of nurse stakeholders are sparse and inconclusive. The purpose of this study was to examine nurse scientists' views on collaborative research as part of a larger study on standards of scientific conduct. Web-based descriptive survey of nurse scientists randomly selected from 50 doctoral graduate programs in the United States. Nearly forty percent of nurse respondents were not able to identify good collaborative practices for the discipline; more than three quarters did not know of any published guidelines available to them. Successful research collaborations were challenged by different expectations of authorship and data ownership, lack of timeliness and communication, poorly defined roles and responsibilities, language barriers, and when they involve junior and senior faculty working together on a project. Individual and organizational standards, practices, and policies for collaborative research needs clarification within the discipline. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Conducting Online Behavioral Research Using Crowdsourcing Services in Japan

    PubMed Central

    Majima, Yoshimasa; Nishiyama, Kaoru; Nishihara, Aki; Hata, Ryosuke

    2017-01-01

    Recent research on human behavior has often collected empirical data from the online labor market, through a process known as crowdsourcing. As well as the United States and the major European countries, there are several crowdsourcing services in Japan. For research purpose, Amazon's Mechanical Turk (MTurk) is the widely used platform among those services. Previous validation studies have shown many commonalities between MTurk workers and participants from traditional samples based on not only personality but also performance on reasoning tasks. The present study aims to extend these findings to non-MTurk (i.e., Japanese) crowdsourcing samples in which workers have different ethnic backgrounds from those of MTurk. We conducted three surveys (N = 426, 453, 167, respectively) designed to compare Japanese crowdsourcing workers and university students in terms of their demographics, personality traits, reasoning skills, and attention to instructions. The results generally align with previous studies and suggest that non-MTurk participants are also eligible for behavioral research. Furthermore, small screen devices are found to impair participants' attention to instructions. Several recommendations concerning this sample are presented. PMID:28382006

  20. Leading Change and Advancing Health by Enhancing Nurses' and Midwives' Knowledge, Ability and Confidence to Conduct Research through a Clinical Scholar Program in Western Australia

    PubMed Central

    Chapman, Rose; Duggan, Ravani; Combs, Shane

    2011-01-01

    This paper reports on an evaluation of a Clinical Scholar Program initiated at a hospital in Western Australia. The aim of the program was to build the capacity of nurses and midwives to conduct research and evidence-based practice within the hospital. The program was based on a previous program and consisted of six teaching days and four hours per month release for proposal preparation. At the end of the program participants were asked to complete a short anonymous questionnaire. The answers were analysed using standard processes of qualitative analysis. Themes emerging from the data included program strengths, individual gains, ability to conduct research, and areas for improvement. The findings highlighted that, while the participants considered that they were more knowledgeable and confident to conduct research, they still required support. The Clinical Scholar Program has provided a way to increase the capacity of clinicians to participate in research activities. PMID:22111024

  1. Leading Change and Advancing Health by Enhancing Nurses' and Midwives' Knowledge, Ability and Confidence to Conduct Research through a Clinical Scholar Program in Western Australia.

    PubMed

    Chapman, Rose; Duggan, Ravani; Combs, Shane

    2011-01-01

    This paper reports on an evaluation of a Clinical Scholar Program initiated at a hospital in Western Australia. The aim of the program was to build the capacity of nurses and midwives to conduct research and evidence-based practice within the hospital. The program was based on a previous program and consisted of six teaching days and four hours per month release for proposal preparation. At the end of the program participants were asked to complete a short anonymous questionnaire. The answers were analysed using standard processes of qualitative analysis. Themes emerging from the data included program strengths, individual gains, ability to conduct research, and areas for improvement. The findings highlighted that, while the participants considered that they were more knowledgeable and confident to conduct research, they still required support. The Clinical Scholar Program has provided a way to increase the capacity of clinicians to participate in research activities.

  2. [Research Conducted at the Institute for Computer Applications in Science and Engineering

    NASA Technical Reports Server (NTRS)

    1997-01-01

    This report summarizes research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, fluid mechanics, and computer science during the period 1 Oct. 1996 - 31 Mar. 1997.

  3. NHS Trusts' clinical research activity and overall CQC performance - Is there a correlation?

    PubMed

    Jonker, L; Fisher, S J

    2015-11-01

    Since the late 2000's, the creation of the National Institute for Health Research (NIHR) has transformed clinical research activity in the United Kingdom. This study sought to establish if there is a link between clinical research activity and overall NHS Trust performance. Retrospective cohort study. Data for NHS Trust performance were obtained from public databases, namely the Care Quality Commission (CQC) 2013 risk rating for overall performance, and 2012-13 NIHR records for clinical research activity. Applying Spearman's rank analysis, none of the Trust categories showed a correlation with CQC risk rating: small hospitals, r = -0.062 (P = 0.76; n = 27); medium, r = -0.224 (P = 0.13; n = 47); large, r = -0.008 (P = 0.96; n = 57); academic, r = -0.18 (P = 0.41; n = 24). Similar results were observed when CQC risk rating was compared with the number of different clinical research studies conducted per Trust. The degree of NIHR National Portfolio clinical research activity is not significantly related to CQC risk rating, used as an indicator of overall NHS Trust performance. Other studies have previously shown that increased research activity correlates with improved mortality rates, one component of CQC risk rating scores. Alternative tools may have to be explored to evaluate the impact of clinical research on NHS Trusts and its patients. Copyright © 2015 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  4. HRP Chief Scientist's Office: Conducting Research to Enable Deep Space Exploration

    NASA Technical Reports Server (NTRS)

    Charles, J. B.; Fogarty, J.; Vega, L.; Cromwell, R. L.; Haven, C. P.; McFather, J. C.; Savelev, I.

    2017-01-01

    The HRP Chief Scientist's Office sets the scientific agenda for the Human Research Program. As NASA plans for deep space exploration, HRP is conducting research to ensure the health of astronauts, and optimize human performance during extended duration missions. To accomplish this research, HRP solicits for proposals within the U.S., collaborates with agencies both domestically and abroad, and makes optimal use of ISS resources in support of human research. This session will expand on these topics and provide an opportunity for questions and discussion with the HRP Chief Scientist. Presentations in this session will include: NRA solicitations - process improvements and focus for future solicitations, Multilateral Human Research Panel for Exploration - future directions (MHRPE 2.0), Extramural liaisons - National Science Foundation (NSF) and Department of Defense (DOD), Standardized Measures for spaceflight, Ground-based Analogs - international collaborations, and International data sharing.

  5. Flowable Conducting Particle Networks in Redox-Active Electrolytes for Grid Energy Storage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hatzell, K. B.; Boota, M.; Kumbur, E. C.

    2015-01-01

    This study reports a new hybrid approach toward achieving high volumetric energy and power densities in an electrochemical flow capacitor for grid energy storage. The electrochemical flow capacitor suffers from high self-discharge and low energy density because charge storage is limited to the available surface area (electric double layer charge storage). Here, we examine two carbon materials as conducting particles in a flow battery electrolyte containing the VO2+/VO2+ redox couple. Highly porous activated carbon spheres (CSs) and multi-walled carbon nanotubes (MWCNTs) are investigated as conducting particle networks that facilitate both faradaic and electric double layer charge storage. Charge storage contributionsmore » (electric double layer and faradaic) are distinguished for flow-electrodes composed of MWCNTs and activated CSs. A MWCNT flow-electrode based in a redox-active electrolyte containing the VO2+/VO2+ redox couple demonstrates 18% less self-discharge, 10 X more energy density, and 20 X greater power densities (at 20 mV s-1) than one based on a non-redox active electrolyte. Furthermore, a MWCNT redox-active flow electrode demonstrates 80% capacitance retention, and >95% coulombic efficiency over 100 cycles, indicating the feasibility of utilizing conducting networks with redox chemistries for grid energy storage.« less

  6. Flowable conducting particle networks in redox-active electrolytes for grid energy storage

    DOE PAGES

    Hatzell, K. B.; Boota, M.; Kumbur, E. C.; ...

    2015-01-09

    This paper reports a new hybrid approach toward achieving high volumetric energy and power densities in an electrochemical flow capacitor for grid energy storage. The electrochemical flow capacitor suffers from high self-discharge and low energy density because charge storage is limited to the available surface area (electric double layer charge storage). Here, we examine two carbon materials as conducting particles in a flow battery electrolyte containing the VO 2+/VO 2 + redox couple. Highly porous activated carbon spheres (CSs) and multi-walled carbon nanotubes (MWCNTs) are investigated as conducting particle networks that facilitate both faradaic and electric double layer charge storage.more » Charge storage contributions (electric double layer and faradaic) are distinguished for flow-electrodes composed of MWCNTs and activated CSs. A MWCNT flow-electrode based in a redox-active electrolyte containing the VO 2+/VO 2 + redox couple demonstrates 18% less self-discharge, 10 X more energy density, and 20 X greater power densities (at 20 mV s -1) than one based on a non-redox active electrolyte. Additionally, a MWCNT redox-active flow electrode demonstrates 80% capacitance retention, and >95% coulombic efficiency over 100 cycles, indicating the feasibility of utilizing conducting networks with redox chemistries for grid energy storage.« less

  7. Practical strategies and perceptions from community pharmacists following their experiences with conducting pharmacy practice research: a qualitative content analysis.

    PubMed

    De Vera, Mary A; Campbell, Natasha K J; Chhina, Harpreet; Galo, Jessica S; Marra, Carlo

    2017-10-26

    While prior research identified barriers to conducting research in community pharmacies, there remains a need to better understand facilitators to ensure successful collaborations between academic researchers and pharmacists. Our objective was to determine the experiences and perspectives of community pharmacists who have recently conducted a pharmacy practice-based research study to gain in-depth understanding of challenges as well as facilitators and identify strategies and solutions. We conducted a qualitative study involving one-on-one semi-structured telephone interviews with community pharmacists following the completion of a practice-based research study in their pharmacies. Interview transcripts were analysed using inductive content analysis involving open coding, creating categories and abstraction into final themes. Eleven pharmacists participated in the qualitative interviews. We identified six major themes including: (1) barriers (e.g. time constraints); (2) facilitators (e.g. ideal pharmacy layout); (3) support and resources from academic researchers (e.g. helpfulness of training, easy-to-use study materials); (4) pharmacist-initiated strategies for conducting research (beyond prior suggestions from researchers); (5) suggestions for future pharmacy practice research; and (6) motivation for conducting pharmacy practice research. These findings informed practical strategies targeted at academic researchers and pharmacists, respectively, to facilitate the conduct of research in community pharmacists across various stages of the research process. Our study adds to better understanding of community pharmacists' perspectives on conducting research and identifies practical solutions that can be readily implemented by academic researchers and pharmacists participating in research. © 2017 Royal Pharmaceutical Society.

  8. Ostracod-inferred conductivity transfer function and its utility in palaeo-conductivity reconstruction in Tibetan Lakes

    NASA Astrophysics Data System (ADS)

    Peng, P.; Zhu, L.; Guo, Y.; Wang, J.; Fürstenberg, S.; Ju, J.; Wang, Y.; Frenzel, P.

    2016-12-01

    Ostracod, was used as a sensitive monitor in palaeo-environmental change research. Ostracod transfer function was developing as a quantitate indicator in palaeo-limnology research. Plenty of lakes scattered on the Tibetan Plateau supplied sediments for analyzing indexes of environment in past climate change research. This application was research on samples of sub-fossil ostracod and its habitat condition, including water sample and water parameters, to produce a database for a forward transfer function based on gradient analyses. This transfer function was used for environment reconstruction of Tibetan lakes to preview past climate changes. In our research, twelve species belonging to ten genus were documented from 114 studied samples in 34 lakes. This research illustrated a specific conductivity gradient gradually increased by L.sinensis-L.dorsotuberosa-C.xizangensis, L.dorsotuberosa-L.inopinata and L.inopinata to indicate fresh-lightly brackish, brackish, brine water condition, respectively. Gradient analysis revealed that specific conductivity was the most important variable drove the distribution of sub-fossil Ostracods. A specific conductivity transfer function using a weighted averaging partial least squares (WA-PLS) model was set up to reconstruct palaeo-specific conductivity. The model presented a good correlation of measured and estimated specific conductivity (R2=0.67), a relative low root mean squared error of prediction (RMSEP=0.47). Multi-proxies, including ostracod assemblages, ostracod-inferred lake level and specific conductivity, mean grain size, total organic carbon and total inorganic carbon of sediment from core of Tibetan Lakes, inferred the palaeo-climate change history of the research area. The environmental change probably was an adaption to the weakening activities of India monsoon since mid-Holocene inferred from the comparable climatic change records from the Tibetan Plateau and relative monsoonal areas.

  9. Transparent Conducting Oxides: Status and Opportunities in Basic Research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Coutts, T. J.; Perkins, J. D.; Ginley, D.S.

    1999-08-01

    In this paper, we begin by discussing the historical background of transparent conducting oxides and then make some general remarks about their typical properties. This is followed by a short discussion of the desired properties for future applications (particularly photovoltaic devices). These are ambitious objectives but they provide targets for future basic research and development. Although it may be possible to obtain these properties in the laboratory, it is vital to ensure that account is taken of industrial perceptions to the development of the next generation of materials. Hence, we spend some time discussing industrial criteria. Next, we discuss keymore » physical properties that determine the macroscopic physical properties that, in turn, affect the performance of devices. Finally, we select several key topics that ought to be included in future basic research programs.« less

  10. Research nurse manager perceptions about research activities performed by non-nurse clinical research coordinators.

    PubMed

    Jones, Carolynn Thomas; Hastings, Clare; Wilson, Lynda Law

    2015-01-01

    There has been limited research to document differences in roles between nurses and non-nurses who assume clinical research coordination and management roles. Several authors have suggested that there is no acknowledged guidance for the licensure requirements for research study coordinators and that some non-nurse research coordinators may be assuming roles that are outside of their legal scopes of practice. There is a need for further research on issues related to the delegation of clinical research activities to non-nurses. This study used nominal group process focus groups to identify perceptions of experienced research nurse managers at an academic health science center in the Southern United States about the clinical research activities that are being performed by non-nurse clinical research coordinators without supervision that they believed should only be performed by a nurse or under the supervision of a nurse. A total of 13 research nurse managers volunteered to be contacted about the study. Of those, 8 participated in two separate nominal group process focus group sessions. The group members initially identified 22 activities that they felt should only be performed by a nurse or under the direct supervision of a nurse. After discussion and clarification of results, activities were combined into 12 categories of clinical research activities that participants believed should only be performed by a nurse or under the direct supervision of a nurse. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Research and technology activities at Ames Research Center's Biomedical Research Division

    NASA Technical Reports Server (NTRS)

    Martello, N.

    1985-01-01

    Various research and technology activities at Ames Research Center's Biomedical Research Division are described. Contributions to the Space Administration's goals in the life sciences include descriptions of research in operational medicine, cardiovascular deconditioning, motion sickness, bone alterations, muscle atrophy, fluid and electrolyte changes, radiation effects and protection, behavior and performance, gravitational biology, and life sciences flight experiments.

  12. The Role of Institutional Research in Conducting Comparative Analysis of Peers

    ERIC Educational Resources Information Center

    Trainer, James F.

    2008-01-01

    In this age of accountability, transparency, and accreditation, colleges and universities increasingly conduct comparative analyses and engage in benchmarking activities. Meant to inform institutional planning and decision making, comparative analyses and benchmarking are employed to let stakeholders know how an institution stacks up against its…

  13. Cohort Profile of the Goals Study: A Large-Scale Research of Physical Activity in Dutch Students

    ERIC Educational Resources Information Center

    de Groot, Renate H. M.; van Dijk, Martin L.; Kirschner, Paul A.

    2015-01-01

    The GOALS study (Grootschalig Onderzoek naar Activiteiten van Limburgse Scholieren [Large-scale Research of Activities in Dutch Students]) was set up to investigate possible associations between different forms of physical activity and inactivity with cognitive performance, academic achievement and mental well-being. It was conducted at a…

  14. A practical field guide to conducting nursing research in low- and middle-income countries.

    PubMed

    LeBaron, Virginia T; Iribarren, Sarah J; Perri, Seneca; Beck, Susan L

    2015-01-01

    The purpose of this report is to offer practical guidance to nurse investigators interested in international research in low- and middle-income countries (LMICs). Lessons learned and strategies for planning and implementing an international research project are addressed. Four nurse researchers who conducted studies in diverse international settings (Argentina, India, South Africa, and Tanzania) describe their collective experiences regarding study planning and implementation; data collection using a variety of methods; and cultural, contextual and ethical considerations. Nurses who undertake international health research projects, particularly in LMICs, can face unique challenges and opportunities. Recommendations for success include advance planning, remaining flexible, having a backup plan, cultivating an attitude of curiosity and cultural humility, establishing collaborative and respectful partnerships, and budgeting adequate time. Nurse scientists often receive little training and support to conduct international research. Guidance to undertake research projects in LMICs can build capacity for nurses to make significant contributions to global health. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. 12 CFR 7.5008 - Location of a national bank conducting electronic activities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Location of a national bank conducting electronic activities. 7.5008 Section 7.5008 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY BANK ACTIVITIES AND OPERATIONS Electronic Activities § 7.5008 Location of a national bank...

  16. 12 CFR 7.5008 - Location of a national bank conducting electronic activities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Location of a national bank conducting electronic activities. 7.5008 Section 7.5008 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY BANK ACTIVITIES AND OPERATIONS Electronic Activities § 7.5008 Location of a national bank...

  17. Trust Building Recruitment Strategies for Researchers Conducting Studies in African American (AA) Churches: Lessons Learned

    PubMed Central

    Bonner, Gloria; Williams, Sharon; Wilkie, Diana; Hart, Alysha; Burnett, Glenda; Peacock, Geraldine

    2017-01-01

    Background An initial and vital important step in recruiting participants for church-based hospice and palliative care research is the establishment of trust and credibility within the church community. Mistrust of medical research is an extremely important barrier hindering recruitment in African American (AA) communities. A church-based EOL dementia education project is currently being conducted at four large urban AA churches. Church leaders voiced mistrust concerns of previous researchers who conducted investigations in their faith-based institutions. We explored strategies to ameliorate the mistrust concerns. Specific aim To identify trust-rebuilding elements for researchers following others who violated trust of AA church leaders. Methods Face-to-face, in-depth interviews were conducted from a convenient sample of four established AA church leaders. Interviews were held in the informants’ churches to promote candor and comfort in revealing sensitive information about trust/mistrust. Content analysis framework was used to analyze the data. Elements identified from the analysis were then used to create themes. Results Multidimensional overarching themes emerged from the analysis included: Experience with researchers (positive and extremely negative), violation of trust and trust building strategies. Conclusions Findings suggest that researchers who wish to conduct successful studies in the AA religious institutions must implement trust rebuilding strategies that include mutual respect, collaboration and partnership building. If general moral practices continue to be violated, threat to future hospice and palliative care research within the institutions may prevail. Thus, potential benefits are thwarted for the church members, AA community, and advancement of EOL care scholarship. PMID:27577723

  18. Trust Building Recruitment Strategies for Researchers Conducting Studies in African American (AA) Churches: Lessons Learned.

    PubMed

    Bonner, Gloria; Williams, Sharon; Wilkie, Diana; Hart, Alysha; Burnett, Glenda; Peacock, Geraldine

    2017-12-01

    An initial and vital important step in recruiting participants for church-based hospice and palliative care research is the establishment of trust and credibility within the church community. Mistrust of medical research is an extremely important barrier hindering recruitment in African American (AA) communities. A church-based EOL dementia education project is currently being conducted at four large urban AA churches. Church leaders voiced mistrust concerns of previous researchers who conducted investigations in their faith-based institutions. We explored strategies to ameliorate the mistrust concerns. Specific aim: To identify trust-rebuilding elements for researchers following others who violated trust of AA church leaders. Face-to-face, in-depth interviews were conducted from a convenient sample of four established AA church leaders. Interviews were held in the informants' churches to promote candor and comfort in revealing sensitive information about trust /mistrust. Content analysis framework was used to analyze the data. Elements identified from the analysis were then used to create themes. Multidimensional overarching themes emerged from the analysis included: Experience with researchers (positive and extremely negative), violation of trust and trust building strategies. Findings suggest that researchers who wish to conduct successful studies in the AA religious institutions must implement trust rebuilding strategies that include mutual respect, collaboration and partnership building. If general moral practices continue to be violated, threat to future hospice and palliative care research within the institutions may prevail. Thus, potential benefits are thwarted for the church members, AA community, and advancement of EOL care scholarship.

  19. Responsible Conduct of Research: Not Just for Researchers

    ERIC Educational Resources Information Center

    Schaller-Demers, Debra S.

    2015-01-01

    Every research institution employs administrative staff who support the research community on a daily basis. Whether in a central office, department, clinic or laboratory, these people may not be aware of the important role they play in safe-guarding the integrity of the research enterprise. Frequently, research administrators are forced to face…

  20. Relating practitioner needs to research activities

    NASA Technical Reports Server (NTRS)

    Feather, M. S.; Menzies, T.; Connelly, J. R.

    2003-01-01

    We present an approach to matching needs (practioner requirements) to solutions (researcher activities). A taxonomical classification scheme acts as intermediary between needs and activities. Expert practitioners exprss their needs in terms of this taxonomy. Researchers express their activities in the same terms. A decision support tool is used to assist in the combination and study of their expressions of needs and activities.

  1. Conducting Human Research

    DTIC Science & Technology

    2009-08-05

    Socio-cultural data acquisition, extraction, and management.??? First the idea of a theoretical framework will be very briefly discussed as well as...SUBJECT TERMS human behavior, theoretical framework , hypothesis development, experimental design, ethical research, statistical power, human laboratory...who throw rocks? • How can we make them stay too far away to throw rocks? UNCLASSIFIED – Approved for Public Release Theoretical Framework / Conceptual

  2. What's so important about conducting research involving third parties?

    PubMed

    Murrelle, L; McCarthy, C R

    2001-01-01

    Controversy has arisen over the long-standing practice of collecting family health and behavioral history information in the course of conducting biomedical research. Identifiable individuals (third parties) on whom investigators collect private data through primary research subjects (probands) also are considered research subjects. At issue is whether informed consent is required from third parties prior to obtaining information about them from probands. A recent federal regulatory ruling dictates that investigators must either obtain informed consent from all third parties or their research must qualify for a waiver of consent. Because of the ruling, a traditional family medical history questionnaire, typical of those routinely used in genetic epidemiologic studies of familial risk, failed to meet the criteria for the waiver. The implications of this ruling are far-reaching. They could influence the quality of research in the United States on the causes of most human diseases. To enable continuing medical and bioethical education on the topic, in March 2001, Virginia Commonwealth University hosted a 2-day open conference, "Third Party Rights and Risks: A Forum on Informed Consent from Persons Affected by the Study of Human Subjects." International leaders from the fields of biomedical ethics and law convened with federal regulatory officials, Institutional Review Board members, academic and industry scientists, and patient-family rights advocates to discuss and debate this critical topic. Conference presenters submitted papers to clarify the issues, promote continued debate, and assist in the formulation of policy recommendations regarding third-party rights and risks.

  3. IAU Project and Research Activity in Nepal

    NASA Astrophysics Data System (ADS)

    Gautam, Suman

    2015-08-01

    The second half of the twentieth century has witnessed a tremendous development in the field of astronomy and space exploration. The large telescope both on the land and in the orbit, using the whole range of the electromagnetic spectra from radio waves to gamma rays are extending their range of exploration, right to the edge of the observable universe, and making astounding discoveries in the process. Many large international telescope facilities and global plans are accessible to all astronomers throughout the world, providing an inexpensive entry to cutting- edge international research for developing countries.Nepal is a mountainous country it has a wide range of climatic and altitude variations which varies from an elevation of 200 meter to ≥ 4000 meter. The average temperature varies from ≥ 25 o C to ≤ 0 to 5oC. Because of these diverse weather and climatic variation there is the potential for the establishment of sophisticated observatory/ data centre and link with each other. So, the future possible opportunity of astronomy in Nepal will be discussed. Besides Education and Research activities conducted in Tribhuvan University, Nepal under the support of International Astronomical Union (IAU) will also be highlighted. The importance brought by those two workshops conducted on data simulation supported by IAU under TF1 will also be discussed which is believed to play a vital role for the promotion and development of astronomy and astrophysics in developing countries.

  4. 34 CFR 97.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... proposals for research to be conducted or supported by a Federal Department or Agency. 97.120 Section 97.120... the Protection of Human Subjects (Basic ED Policy for Protection of Human Research Subjects) § 97.120 Evaluation and disposition of applications and proposals for research to be conducted or supported by a...

  5. How to conduct a high-quality original study on a diagnostic research topic.

    PubMed

    Yao, Xiaomei; Vella, Emily

    2017-09-01

    As health research methodologists and journal reviewers, we noticed that the methodological rigor of many publications on diagnostic or prognostic topics in the medical literature could be improved. We present a concise and clear series of reviews to help clinicians and health researchers to master the basic key components of how to conduct a high-quality original study or systematic review on a diagnostic or prognostic research topic from a methodological perspective. This is the first review of the series, which focuses on how to conduct a high-quality diagnostic study. We are introducing four aspects: clarifying the objectives; generating an appropriate research question; planning the study design; and reporting and analyzing data. This review highlights that diagnostic test accuracy outcomes are surrogates for patient outcomes, a diagnostic test has three roles, the "PIRO" components should be included in a diagnostic research question, a new study should be registered, multiple index tests can be compared in one study, and prevalence affects test accuracy outcomes. This review also emphasizes reporting any thresholds, calculating sample size, and performing a two-by-three table to calculate diagnostic outcomes. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. 45 CFR 46.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... proposals for research to be conducted or supported by a Federal Department or Agency. 46.120 Section 46.120... SUBJECTS Basic HHS Policy for Protection of Human Research Subjects § 46.120 Evaluation and disposition of applications and proposals for research to be conducted or supported by a Federal Department or Agency. (a) The...

  7. Comorbidity of Anxiety and Conduct Problems in Children: Implications for Clinical Research and Practice

    ERIC Educational Resources Information Center

    Cunningham, Natoshia Raishevich; Ollendick, Thomas H.

    2010-01-01

    Given the relative lack of research on the comorbidity of anxiety disorders (ADs) and conduct problems (oppositional defiant disorder, conduct disorder) in youth, we examine this comorbidity from both basic and applied perspectives. First, we review the concept of comorbidity and provide a framework for understanding issues pertaining to…

  8. 22 CFR 225.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., appropriate for the research in question, on file with the Office for Human Research Protections, HHS, or any... Human Research Protections, HHS, or any successor office. (b) Departments and agencies will conduct or... responsibilities for protecting the rights and welfare of human subjects of research conducted at or sponsored by...

  9. 40 CFR 26.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Protection of Subjects in Human Research Conducted or Supported by EPA § 26.103 Assuring compliance with this..., appropriate for the research in question, on file with the Office for Human Research Protections, HHS, or any... Human Research Protections, HHS, or any successor office. (b) Departments and agencies will conduct or...

  10. 28 CFR 46.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., appropriate for the research in question, on file with the Office for Human Research Protections, HHS, or any... Human Research Protections, HHS, or any successor office. (b) Departments and agencies will conduct or... responsibilities for protecting the rights and welfare of human subjects of research conducted at or sponsored by...

  11. 16 CFR 1028.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., appropriate for the research in question, on file with the Office for Human Research Protections, HHS, or any... Human Research Protections, HHS, or any successor office. (b) Departments and agencies will conduct or... responsibilities for protecting the rights and welfare of human subjects of research conducted at or sponsored by...

  12. 15 CFR 27.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., appropriate for the research in question, on file with the Office for Human Research Protections, HHS, or any... Human Research Protections, HHS, or any successor office. (b) Departments and agencies will conduct or... responsibilities for protecting the rights and welfare of human subjects of research conducted at or sponsored by...

  13. 49 CFR 11.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., appropriate for the research in question, on file with the Office for Human Research Protections, HHS, or any... Human Research Protections, HHS, or any successor office. (b) Departments and agencies will conduct or... responsibilities for protecting the rights and welfare of human subjects of research conducted at or sponsored by...

  14. Separate Cl^- Conductances Activated by cAMP and Ca2+ in Cl^--Secreting Epithelial Cells

    NASA Astrophysics Data System (ADS)

    Cliff, William H.; Frizzell, Raymond A.

    1990-07-01

    We studied the cAMP- and Ca2+-activated secretory Cl^- conductances in the Cl^--secreting colonic epithelial cell line T84 using the whole-cell patch-clamp technique. Cl^- and K^+ currents were measured under voltage clamp. Forskolin or cAMP increased Cl^- current 2-15 times with no change in K^+ current. The current-voltage relation for cAMP-activated Cl^- current was linear from -100 to +100 mV and showed no time-dependent changes in current during voltage pulses. Ca2+ ionophores or increased pipette Ca2+ increased both Cl^- and K^+ currents 2-30 times. The Ca2+-activated Cl^- current was outwardly rectified, activated during depolarizing voltage pulses, and inactivated during hyperpolarizing voltage pulses. Addition of ionophore after forskolin further increased Cl^- conductance 1.5-5 times, and the current took on the time-dependent characteristics of that stimulated by Ca2+. Thus, cAMP and Ca2+ activate Cl^- conductances with different properties, implying that these second messengers activate different Cl^- channels or that they induce different conductive and kinetic states in the same Cl^- channel.

  15. Non-Arrhenius ionic conductivities in glasses due to a distribution of activation energies.

    PubMed

    Bischoff, C; Schuller, K; Beckman, S P; Martin, S W

    2012-08-17

    Previously observed non-Arrhenius behavior in fast ion conducting glasses [J. Kincs and S. W. Martin, Phys. Rev. Lett. 76, 70 (1996)] occurs at temperatures near the glass transition temperature, T(g), and is attributed to changes in the ion mobility due to ion trapping mechanisms that diminish the conductivity and result in a decreasing conductivity with increasing temperature. It is intuitive that disorder in glass will also result in a distribution of the activation energies (DAE) for ion conduction, which should increase the conductivity with increasing temperature, yet this has not been identified in the literature. In this Letter, a series of high precision ionic conductivity measurements are reported for 0.5Na(2)S + 0.5[xGeS(2) + (1-x)PS(5/2)] glasses with compositions ranging from 0 ≤ x ≤ 1. The impact of the cation site disorder on the activation energy is identified and explained using a DAE model. The absence of the non-Arrhenius behavior in other glasses is explained and it is predicted which glasses are expected to accentuate the DAE effect on the ionic conductivity.

  16. Semantic Support Environment for Research Activity

    ERIC Educational Resources Information Center

    Ismail, Maizatul Akmar; Yaacob, Mashkuri; Kareem, Sameem Abdul

    2008-01-01

    Scholarly activities are a collection of academic related activities such as research, teaching and consultation work which result in research outputs such as journals, theses and articles in proceedings. The output will then be disseminated to researchers all over the world by means of the WWW. The four pillars of this scholarship i.e. discovery,…

  17. Value and challenges of conducting rapid response research on wildland fires

    Treesearch

    L. Lentile; P. Morgan; C. Hardy; A. Hudak; R. Means; R. Ottmar; P. Robichaud; E. Kennedy Sutherland; J. Szymoniak; F. Way; J. Fites-Kaufman; S. Lewis; E. Mathews; H. Shovik; K. Ryan

    2007-01-01

    Rapid Response Research is conducted during and immediately after wildland fires, in coordination with fire management teams, in order to collect information that can best be garnered in situ and in real-time. This information often includes fire behavior and fire effects data, which can be used to generate practical tools such as predictive fire models for managers....

  18. The development of scientific identification theory to conduct operation research in education management

    NASA Astrophysics Data System (ADS)

    Hardhienata, S.

    2017-01-01

    Operations research is a general method used in the study and optimization of a system through modeling of the system. In the field of education, especially in education management, operations research has not been widely used. This paper gives an exposition of ideas about how operations research can be used to conduct research and optimization in the field of education management by developing SITOREM (Scientific Identification Theory for Operation Research in Education Management). To clarify the intent of the idea, an example of applying SITOREM to enhance the professional commitment of lecturers associated with achieving the vision of university will be described.

  19. Antiviral drug research proposal activity.

    PubMed

    Injaian, Lisa; Smith, Ann C; Shipley, Jennifer German; Marbach-Ad, Gili; Fredericksen, Brenda

    2011-01-01

    The development of antiviral drugs provides an excellent example of how basic and clinical research must be used together in order to achieve the final goal of treating disease. A Research Oriented Learning Activity was designed to help students to better understand how basic and clinical research can be combined toward a common goal. Through this project students gained a better understanding of the process of scientific research and increased their information literacy in the field of virology. The students worked as teams to research the many aspects involved in the antiviral drug design process, with each student becoming an "expert" in one aspect of the project. The Antiviral Drug Research Proposal (ADRP) culminated with students presenting their proposals to their peers and local virologists in a poster session. Assessment data showed increased student awareness and knowledge of the research process and the steps involved in the development of antiviral drugs as a result of this activity.

  20. Action research in radiography: What it is and how it can be conducted

    PubMed Central

    Munn, Zachary; Pearson, Alan; Jordan, Zoe; Murphy, Frederick; Pilkington, Diana

    2013-01-01

    Action research is a form of research that investigates and describes a social or work situation with the aim of achieving a change which results in improvement. This article emphasizes the potential for action research to be a useful research method in radiography. A search was conducted to determine the extent to which action research has been utilized in radiography. Although action research has been used in a number of health-care settings, there are no published examples of action research being utilized in a clinical medical imaging department. Action research is discussed in detail, along with an example guide for an action research study. Action research has been identified as a useful way to affect change, to involve radiographers in the research process, and to introduce evidence-based practice to radiography. PMID:26229607

  1. Activities report of PTT Research

    NASA Astrophysics Data System (ADS)

    In the field of postal infrastructure research, activities were performed on postcode readers, radiolabels, and techniques of operations research and artificial intelligence. In the field of telecommunication, transportation, and information, research was made on multipurpose coding schemes, speech recognition, hypertext, a multimedia information server, security of electronic data interchange, document retrieval, improvement of the quality of user interfaces, domotics living support (techniques), and standardization of telecommunication prototcols. In the field of telecommunication infrastructure and provisions research, activities were performed on universal personal telecommunications, advanced broadband network technologies, coherent techniques, measurement of audio quality, near field facilities, local beam communication, local area networks, network security, coupling of broadband and narrowband integrated services digital networks, digital mapping, and standardization of protocols.

  2. 42 CFR 51.31 - Conduct of protection and advocacy activities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... to mental health system improvement. Decisions concerning the selection of individuals to receive... 42 Public Health 1 2010-10-01 2010-10-01 false Conduct of protection and advocacy activities. 51.31 Section 51.31 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS...

  3. An Online Course for Instruction in the Reponsible Conduct of Research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Michael Kalichman

    2004-10-12

    Responsible Conduct of Research (RCR) is the process by which regulations, guidelines, standards and ethics are reconciled to promote integrity in research. The development of this online resource, with contributions from the Department of Health and Human Services (DHHS), will allow the DOE system to offer state-of-the-art education in RCR to its sites. The intent of the project is to establish basic RCR content websites, publicize for public use and review, revise as recommended or as ethics change, and to continue supplementing with new material. The resulting resources will be posted on the Web (http://rcrec.org/r)

  4. Conducting Mathematical Research with Undergraduates

    ERIC Educational Resources Information Center

    Roberts, Gareth E.

    2013-01-01

    The notion that undergraduates are capable of making profound and original contributions to mathematical research is rapidly gaining acceptance. Undergraduates bring their enthusiasm, creativity, curiosity, and perseverance to bona fide research problems. This article discusses some of the key issues concerning undergraduate mathematical research:…

  5. Research on thermal conductivity of HGMs at vacuum in room temperature

    NASA Astrophysics Data System (ADS)

    Wang, Ping; Liao, Bin; An, Zhenguo; Yan, Kaiqi; Zhang, Jingjie

    2018-05-01

    Hollow glass microspheres (HGMs) can be used as thermal insulation materials owing to its hollow structure which brings excellent thermal insulation property and low density. At present, most researches on thermal conductivity of HGMs are focused on polymer matrix/HGMs composite materials. However, thermal conductivity of HGMs at vacuum in room temperature has rarely been investigated. In this work, thermal conductivity of six types of HGMs (T17 (0.17g/cm3), T20 (0.20g/cm3), T22 (0.22g/cm3), T25 (0.25g/cm3), T32 (0.32g/cm3) and T40 (0.40g/cm3)) at vacuum in room temperature were calculated by heat transfer of solid conduction and radiation. The calculation results showed that thermal conductivity of HGMs would be decreased by an order of magnitude compared with no vacuum. In order to verify the calculation and study vacuum thermal insulation properties of HGMs, thermal conductivity of above-mentioned HGMs at no vacuum and high vacuum in room temperature were measured by a self-made thermal conductivity measuring apparatus which was based on the transient plane source (TPS) method. The experimental results showed that thermal conductivity of HGMs were in the range of 4.2030E-02 to 6.3300E-02 W/m.K (at no vacuum) and 3.8160E-03 to 4.9660E-03 W/m.K (at high vacuum). The results indicated that experimental thermal conductivity was consistent with the calculation results and both of them were all decreased by 8-13 times at vacuum compared with no vacuum. In addition, the relationship with physical properties and thermal conductivity of HGMs has been discussed in detail. In conclusion, HGMs possess excellent thermal insulation performance at high vacuum in room temperature and have potential to further reduce thermal conductivity at the same conditions.

  6. Barriers to conducting research: A survey of trainees in emergency medicine.

    PubMed

    Olaussen, Alexander; Jennings, Paul A; O'Reilly, Gerard; Mitra, Biswadev; Cameron, Peter A

    2017-04-01

    Research underpins evidence-based practice, but there are significant barriers to conducting research relevant to each clinical discipline. Understanding these barriers could allow strategies to reduce their impact. The present study was undertaken to understand specific barriers to research for emergency medicine (EM) trainees. EM trainees attending research short courses were surveyed. Free-text responses were classified into themes and a list of pre-specified potential barriers was used for ranking purposes. The responders (n = 61/90; 67.8%) were young, mostly male with low confidence in leading a research project and limited previous research experience. There were 155 unique barriers identified from 55 respondents, which fitted into nine categories. The most frequently perceived barrier was time (29%), followed by skills (22.6%) and cultural factors (19.4%). Most trainees (n = 54/56, 96.4%) believed that the barriers could be overcome. Strategies suggested included protection of time, mentoring and education, as well as top-down improved research culture. Barriers to research in EM are similar to other specialities and were perceived to be manageable. Reorganisation and refocus of the Australasian College for Emergency Medicine training curriculum may be an option to foster an environment to promote research. © 2017 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

  7. Considerations for Conducting Plant Research in Open Atmosphere Chambers on ISS

    NASA Astrophysics Data System (ADS)

    Wheeler, Raymond; Hummerick, Mary; Graham, Thomas; Dixit, Anirudha; Massa, Gioia

    The access to spaceflight and now the International Space Station has provided plant researchers a laboratory that is in continuous freefall (near weightlessness). As veteran spaceflight investigators know too well, research in space is difficult to conduct and the experiments are often confounded by secondary events. An example of this is the distribution of water and gases in rooting systems in µ-gravity. Since the water does not settle to the ”bottom” of the rooting media in space, there can be poor distribution and movement of water and oxygen, which in turn can stress the plants. This also creates challenges for conducting ground controls where the logical approach is to use the same volume of water as in space. But under 1-g, the water does settle to the bottom of the root zone, which leaves less in the upper profile of the rooting medium. In addition, some chambers such as the Russian Svet (on Mir), Lada (ISS), and NASA’s Veggie chamber were or are open to the cabin air. This simplifies the hardware development and allows the use of cabin air for cooling and supplying CO2 to the plants. Yet it also exposes the plants to the cabin air, which could have very high CO2 levels (e.g., 3000 to 6000 ppm), low humidity, and trace contaminants that might be below the limits for human concerns but could still affect plants. A known effect of these “super-elevated” CO2 levels on many dicot species is increased transpiration due to elevated stomatal conductance, both during the light and the dark cycles. Examples of these secondary effects will be discussed, along with potential approaches for conducting adequate ground controls.

  8. 78 FR 9108 - Proposed Information Collection (Conduct the Point-of-Care Research Questionnaire) Activity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-07

    ... patient and provider attitudes and willingness to participate in Point-of-Care Research (POC-R). POC-R is... of a Point-of-care research innovation program by assessing the perceptions and attitudes of patients...

  9. Challenges in conducting community-driven research created by differing ways of talking and thinking about science: a researcher's perspective.

    PubMed

    Colquhoun, Amy; Geary, Janis; Goodman, Karen J

    2013-01-01

    Increasingly, health scientists are becoming aware that research collaborations that include community partnerships can be an effective way to broaden the scope and enhance the impact of research aimed at improving public health. Such collaborations extend the reach of academic scientists by integrating a variety of perspectives and thus strengthening the applicability of the research. Communication challenges can arise, however, when attempting to address specific research questions in these collaborations. In particular, inconsistencies can exist between scientists and community members in the use and interpretation of words and other language features, particularly when conducting research with a biomedical component. Additional challenges arise from differing perceptions of the investigative process. There may be divergent perceptions about how research questions should and can be answered, and in expectations about requirements of research institutions and research timelines. From these differences, misunderstandings can occur about how the results will ultimately impact the community. These communication issues are particularly challenging when scientists and community members are from different ethnic and linguistic backgrounds that may widen the gap between ways of talking and thinking about science, further complicating the interactions and exchanges that are essential for effective joint research efforts. Community-driven research that aims to describe the burden of disease associated with Helicobacter pylori infection is currently underway in northern Aboriginal communities located in the Yukon and Northwest Territories, Canada, with the goal of identifying effective public health strategies for reducing health risks from this infection. This research links community representatives, faculty from various disciplines at the University of Alberta, as well as territorial health care practitioners and officials. This highly collaborative work will be used to

  10. Lessons Learned: Conducting Research With Victims Portrayed in Sexual Abuse Images and Their Parents.

    PubMed

    Walsh, Wendy A; Wolak, Janis; Lounsbury, Kaitlin; Howley, Susan; Lippert, Tonya; Thompson, Lawrence

    2016-03-27

    Victims portrayed in sexual abuse images may be resistant to participate in research because of embarrassment or shame due to the sensitive nature and potential permanency of images. No studies we are aware of explore reactions to participating in research after this type of crime. Telephone interviews were conducted with convenience samples of parents (n= 46) and adolescents who were victims of child sexual abuse (n= 11; some of whom were portrayed in sexual abuse images), and online surveys were completed by adult survivors depicted in abuse images (N= 133). The first lesson was that few agencies tracked this type of crime. This lack of tracking raises the question as to what types of data should be collected and tracked as part of an investigation. The second lesson was that few victims at the two participating agencies had been portrayed in sexual abuse images (4%-5%). The third lesson was that once possible cases were identified, we found relatively high percentages of consent to contact and interview completions. This implies that researchers and service providers should not be hesitant about conducting research after an investigation of child sexual abuse. The fourth lesson was that the vast majority of participants reported not being upset by the questions. We hope that the data presented here will encourage agencies to reconsider the types of data being tracked and will encourage researchers to conduct in-depth research with populations that are often difficult to reach to continue improving the professional response to child victimization. © The Author(s) 2016.

  11. Using Actively Heated Fibre Optics (AHFO) to determine soil thermal conductivity and soil moisture content at high spatial and temporal resolution

    NASA Astrophysics Data System (ADS)

    Ciocca, Francesco; Abesser, Corinna; Hannah, David; Blaen, Philip; Chalari, Athena; Mondanos, Michael; Krause, Stefan

    2017-04-01

    Optical fibre distributed temperature sensing (DTS) is increasingly used in environmental monitoring and for subsurface characterisation, e.g. to obtain precise measurements of soil temperature at high spatio-temporal resolution, over several kilometres of optical fibre cable. When combined with active heating of metal elements embedded in the optical fibre cable (active-DTS), the temperature response of the soil to heating provides valuable information from which other important soil parameters, such as thermal conductivity and soil moisture content, can be inferred. In this presentation, we report the development of an Actively Heated Fibre Optics (AHFO) method for the characterisation of soil thermal conductivity and soil moisture dynamics at high temporal and spatial resolutions at a vegetated hillslope site in central England. The study site is located within a juvenile forest adjacent to the Birmingham Institute of Forest Research (BIFoR) experimental site. It is instrumented with three loops of a 500m hybrid-optical cable installed at 10cm, 25cm and 40cm depths. Active DTS surveys were undertaken in June and October 2016, collecting soil temperature data at 0.25m intervals along the cable, prior to, during and after the 900s heating phase. Soil thermal conductivity and soil moisture were determined according to Ciocca et al. 2012, applied to both the cooling and the heating phase. Independent measurements of soil thermal conductivity and soil moisture content were collected using thermal needle probes, calibrated capacitance-based probes and laboratory methods. Results from both the active DTS survey and independent in-situ and laboratory measurements will be presented, including the observed relationship between thermal conductivity and moisture content at the study site and how it compares against theoretical curves used by the AHFO methods. The spatial variability of soil thermal conductivity and soil moisture content, as observed using the different

  12. Ethical decision making in the conduct of research: role of individual, contextual and organizational factors. Commentary on "Science, human nature, and a new paradigm for ethics education".

    PubMed

    Langlais, Philip J

    2012-09-01

    Despite the importance of scientific integrity to the well-being of society, recent findings suggest that training and mentoring in the responsible conduct of research are not very reliable or effective inhibitors of research misbehavior. Understanding how and why individual scientists decide to behave in ways that conform to or violate norms and standards of research is essential to the development of more effective training programs and the creation of more supportive environments. Scholars in business management, psychology, and other disciplines have identified many important factors that affect ethical behavior, including individual, contextual, and organizational factors. Surprisingly little research has been conducted to examine the role of these factors in either the development of ethical decision-making skills, or their applicability to ethical issues commonly encountered in research and other scholarly and professional activities. Interdisciplinary approaches combined with research and discipline relevant paradigms should greatly enhance understanding of the individual contextual and organizational factors involved in ethical and unethical research conduct. Such studies will inform and facilitate the development of more effective ethics education programs in the sciences and engineering professions.

  13. Hierarchical nanostructured conducting polymer hydrogel with high electrochemical activity

    PubMed Central

    Pan, Lijia; Yu, Guihua; Zhai, Dongyuan; Lee, Hye Ryoung; Zhao, Wenting; Liu, Nian; Wang, Huiliang; Tee, Benjamin C.-K.; Shi, Yi; Cui, Yi; Bao, Zhenan

    2012-01-01

    Conducting polymer hydrogels represent a unique class of materials that synergizes the advantageous features of hydrogels and organic conductors and have been used in many applications such as bioelectronics and energy storage devices. They are often synthesized by polymerizing conductive polymer monomer within a nonconducting hydrogel matrix, resulting in deterioration of their electrical properties. Here, we report a scalable and versatile synthesis of multifunctional polyaniline (PAni) hydrogel with excellent electronic conductivity and electrochemical properties. With high surface area and three-dimensional porous nanostructures, the PAni hydrogels demonstrated potential as high-performance supercapacitor electrodes with high specific capacitance (∼480 F·g-1), unprecedented rate capability, and cycling stability (∼83% capacitance retention after 10,000 cycles). The PAni hydrogels can also function as the active component of glucose oxidase sensors with fast response time (∼0.3 s) and superior sensitivity (∼16.7 μA·mM-1). The scalable synthesis and excellent electrode performance of the PAni hydrogel make it an attractive candidate for bioelectronics and future-generation energy storage electrodes. PMID:22645374

  14. Comparative Effectiveness Research: A Roadmap for Physical Activity and Lifestyle

    PubMed Central

    Jakicic, John M.; Sox, Harold; Blair, Steven N.; Bensink, Mark; Johnson, William G.; King, Abby C.; Lee, I-Min; Nahum-Shani, Inbal; Sallis, James F.; Sallis, Robert E.; Craft, Lynette; Whitehead, James R.; Ainsworth, Barbara E.

    2017-01-01

    Purpose Comparative Effectiveness Research (CER) is designed to support informed decision making at both the individual, population, and policy levels. The American College of Sports Medicine and partners convened a conference with the focus of building an agenda for CER within the context of physical activity and non-pharmacological lifestyle approaches in the prevention and treatment of chronic disease. This report summarizes the conference content and consensus recommendations that culminated in a CER Roadmap for Physical Activity and Lifestyle approaches to reducing the risk of chronic disease. Methods This conference focused on presentations and discussion around the following topic areas: 1) defining CER, 2) identifying the current funding climate to support CER, 3) summarizing methods for conducting CER, and 4) identifying CER opportunities for physical activity. Results This conference resulted in consensus recommendations to adopt a CER Roadmap for Physical Activity and Lifestyle approaches to reducing the risk of chronic disease. In general, this roadmap provides a systematic framework by which CER for physical activity can move from a planning phase, to a phase of engagement in CER related to lifestyle factors with particular emphasis on physical activity, to a societal change phase that results in changes in policy, practice, and health. Conclusions It is recommended that physical activity researchers and healthcare providers use the roadmap developed from this conference as a method to systematically engage in and apply CER to the promotion of physical activity as a key lifestyle behavior that can be effective at impacting a variety of health-related outcomes. PMID:25426735

  15. Research ethics I: Responsible conduct of research (RCR)--historical and contemporary issues pertaining to human and animal experimentation.

    PubMed

    Horner, Jennifer; Minifie, Fred D

    2011-02-01

    In this series of articles--Research Ethics I, Research Ethics II, and Research Ethics III--the authors provide a comprehensive review of the 9 core domains for the responsible conduct of research (RCR) as articulated by the Office of Research Integrity. In Research Ethics I, they present a historical overview of the evolution of RCR in the United States then examine the evolution of human and animal experimentation from the birth of scientific medicine through World War II to the present day. They relied on authoritative documents, both historical and contemporary, insightful commentary, and empirical research in order to identify current issues and controversies of potential interest to both faculty and students. The authors have written this article from a historical perspective because they think all readers interested in RCR should appreciate how the history of science and all the good--and harm--it has produced can inform how researchers practice responsible research in the 21st century and beyond.

  16. Increasing value and reducing waste in research design, conduct, and analysis.

    PubMed

    Ioannidis, John P A; Greenland, Sander; Hlatky, Mark A; Khoury, Muin J; Macleod, Malcolm R; Moher, David; Schulz, Kenneth F; Tibshirani, Robert

    2014-01-11

    Correctable weaknesses in the design, conduct, and analysis of biomedical and public health research studies can produce misleading results and waste valuable resources. Small effects can be difficult to distinguish from bias introduced by study design and analyses. An absence of detailed written protocols and poor documentation of research is common. Information obtained might not be useful or important, and statistical precision or power is often too low or used in a misleading way. Insufficient consideration might be given to both previous and continuing studies. Arbitrary choice of analyses and an overemphasis on random extremes might affect the reported findings. Several problems relate to the research workforce, including failure to involve experienced statisticians and methodologists, failure to train clinical researchers and laboratory scientists in research methods and design, and the involvement of stakeholders with conflicts of interest. Inadequate emphasis is placed on recording of research decisions and on reproducibility of research. Finally, reward systems incentivise quantity more than quality, and novelty more than reliability. We propose potential solutions for these problems, including improvements in protocols and documentation, consideration of evidence from studies in progress, standardisation of research efforts, optimisation and training of an experienced and non-conflicted scientific workforce, and reconsideration of scientific reward systems. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Reprioritizing current research trends in medical education: a reflection on research activities in Saudi Arabia.

    PubMed

    Obeidat, Akef S; Alhaqwi, Ali Ibrahim; Abdulghani, Hamza Mohammad

    2015-04-01

    There are numerous national efforts to determine and develop research priorities of medical education in Saudi Arabia. These priorities were first proposed in 2010 by "Dr Al-Khuli's Chair for Developing Medical Education in Saudi Arabia". The proposed priority domains were: curriculum, students, faculty, and quality assurance and accreditation. To investigate publications in medical education at the national and international levels in areas relating to these proposed priorities. Electronic search within PubMed database for papers relating to each domain of priority was conducted at national and international levels in the last three years, using the same keywords as the priority domains, but only confined to undergraduate medical education. Out of 3145 articles retrieved when searching with keyword as broad as "undergraduate medical curriculum" only 81 articles worldwide and 3 articles from Saudi Arabia were dealing with curriculum related issues as a whole. Further search on the sub-domains "effective strategies to manage undergraduate curriculum" and "undergraduate medical education models", resulted in the retrieval of few articles worldwide and none from Saudi Arabia. At the national level, there were 63 publications from Saudi Arabia that were either course (topic)-specific or could not be classified under the four domains specified by Dr Al-Khuli's Chair. Research activities in medical education in Saudi Arabia in the last 3 years showed diversity and lack of focus in the research priorities. Efforts of academic and research centers should continue to monitor and encourage these activities toward achieving the recommended priorities.

  18. Developmental Pathways to Conduct Disorder: Implications for Future Directions in Research, Assessment, and Treatment

    ERIC Educational Resources Information Center

    Frick, Paul J.

    2012-01-01

    Research has indicated that there are several common pathways through which children and adolescents develop conduct disorder, each with different risk factors and each with different underlying developmental mechanisms leading to the child's aggressive and antisocial behavior. The current article briefly summarizes research on these pathways,…

  19. The National Trauma Institute: Lessons learned in the funding and conduct of 16 trauma research studies.

    PubMed

    Price, Michelle A; Beilman, Gregory J; Fabian, Timothy C; Hoyt, David B; Jurkovich, Gregory J; Knudson, M Margaret; MacKenzie, Ellen J; Marshall, Vivienne S; Overton, Kimberly E; Peitzman, Andrew B; Phillips, Monica J; Pruitt, Basil A; Smith, Sharon L; Stewart, Ronald M; Jenkins, Donald H

    2016-09-01

    To increase trauma-related research and elevate trauma on the national research agenda, the National Trauma Institute (NTI) issued calls for proposals, selected funding recipients, and coordinated 16 federally funded (Department of Defense) trauma research awards over a 4-year period. We sought to collect and describe the lessons learned from this activity to inform future researchers of barriers and facilitators. Fifteen principal investigators participated in semistructured interviews focused on study management issues such as securing institutional approvals, screening and enrollment, multisite trials management, project funding, staffing, and institutional support. NTI Science Committee meeting minutes and study management data were included in the analysis. Simple descriptive statistics were generated and textual data were analyzed for common themes. Principal investigators reported challenges in obtaining institutional approvals, delays in study initiation, screening and enrollment, multisite management, and study funding. Most were able to successfully resolve challenges and have been productive in terms of scholarly publications, securing additional research funding, and training future trauma investigators. Lessons learned in the conduct of the first two funding rounds managed by NTI are instructive in four key areas: regulatory processes, multisite coordination, adequate funding, and the importance of an established research infrastructure to ensure study success. Recommendations for addressing institution-related and investigator-related challenges are discussed along with ongoing advocacy efforts to secure sustained federal funding of a national trauma research program commensurate with the burden of injury.

  20. Provision of community-wide benefits in public health intervention research: the experience of investigators conducting research in the community setting in South Asia.

    PubMed

    Taylor, Holly A; Merritt, Maria W

    2012-12-01

    This article describes the types of community-wide benefits provided by investigators conducting public health research in South Asia as well as their self-reported reasons for providing such benefits. We conducted 52 in-depth interviews to explore how public health investigators in low-resource settings make decisions about the delivery of ancillary care to research subjects. In 39 of the interviews respondents described providing benefits to members of the community in which they conducted their study. We returned to our narrative dataset to find answers to two questions: What types of community-wide benefits do researchers provide when conducting public health intervention studies in the community setting, and what reasons do researchers give when asked why they provided community-wide benefits? The types of community-wide benefits delivered were directed to the health and well-being of the population. The most common types of benefits delivered were the facilitation of access to health care for individuals in acute medical need and emergency response to natural disasters. Respondents' self-reported reasons when asked why they provided such benefits fell into 2 general categories: intrinsic importance and instrumental importance. © 2012 Blackwell Publishing Ltd.

  1. Pharmacogenetic research activity in Central America and the Caribbean: a systematic review

    PubMed Central

    Céspedes-Garro, Carolina; Naranjo, María-Eugenia G; Rodrigues-Soares, Fernanda; LLerena, Adrián; Duconge, Jorge; Montané-Jaime, Lazara K; Roblejo, Hilda; Fariñas, Humberto; Campos, María de los A; Ramírez, Ronald; Serrano, Víctor; Villagrán, Carmen I; Peñas-LLedó, Eva M

    2016-01-01

    Aim: The present review was aimed at analyzing the pharmacogenetic scientific activity in Central America and the Caribbean. Materials & methods: A literature search for pharmacogenetic studies in each country of the region was conducted on three databases using a list of the most relevant pharmacogenetic biomarkers including ‘phenotyping probe drugs’ for major drug metabolizing enzymes. The review included 132 papers involving 47 biomarkers and 35,079 subjects (11,129 healthy volunteers and 23,950 patients). Results: The country with the most intensive pharmacogenetic research was Costa Rica. The most studied medical therapeutic area was oncology, and the most investigated biomarkers were CYP2D6 and HLA-A/B. Conclusion: Research activity on pharmacogenetics in Central American and the Caribbean populations is limited or absent. Therefore, strategies to promote effective collaborations, and foster interregional initiatives and research efforts among countries from the region could help for the rational clinical implementation of pharmacogenetics and personalized medicine. PMID:27633613

  2. Restitution of the research data in ethnographic health research: issues for debate based on field research conducted in Brazil and France.

    PubMed

    Ferreira, Jaqueline

    2015-09-01

    This study examines relevant aspects about the way anthropological research data restitution has been applied in the area of health, based on data obtained from ethnographic field research conducted in Brazil and France. These experiences show that data restitution has been part of the area of research, in different forms and time frames, making it possible to extend periods spent in the field and to interact with individual respondents. This also made it possible to interact with research interlocutors and compare different points of view, adding new information and thereby enriching the research. These aspects raise important questions that require reflection, from an ethical and epistemological standpoint. One is related to the demands made on health anthropologists when they begin their field research and how they deal with these questions: how will researchers use the data they collect without worrying that this may be wrongly interpreted or used in some way to reinforce normative patterns? So, how should an anthropological debate be "translated"? Conscientious researchers will seek to validate their analysis, to discover new points of view and provoke new lines of questioning. Thus, such data should provoke reflexivity about new avenues of research and interpretations.

  3. Research Activity and the Association with Mortality

    PubMed Central

    Ozdemir, Baris A.; Karthikesalingam, Alan; Sinha, Sidhartha; Poloniecki, Jan D.; Hinchliffe, Robert J.; Thompson, Matt M.; Gower, Jonathan D.; Boaz, Annette; Holt, Peter J. E.

    2015-01-01

    Introduction The aims of this study were to describe the key features of acute NHS Trusts with different levels of research activity and to investigate associations between research activity and clinical outcomes. Methods National Institute for Health Research (NIHR) Comprehensive Clinical Research Network (CCRN) funding and number of patients recruited to NIHR Clinical Research Network (CRN) portfolio studies for each NHS Trusts were used as markers of research activity. Patient-level data for adult non-elective admissions were extracted from the English Hospital Episode Statistics (2005-10). Risk-adjusted mortality associations between Trust structures, research activity and, clinical outcomes were investigated. Results Low mortality Trusts received greater levels of funding and recruited more patients adjusted for size of Trust (n = 35, 2,349 £/bed [95% CI 1,855–2,843], 5.9 patients/bed [2.7–9.0]) than Trusts with expected (n = 63, 1,110 £/bed, [864–1,357] p<0.0001, 2.6 patients/bed [1.7–3.5] p<0.0169) or, high (n = 42, 930 £/bed [683–1,177] p = 0.0001, 1.8 patients/bed [1.4–2.1] p<0.0005) mortality rates. The most research active Trusts were those with more doctors, nurses, critical care beds, operating theatres and, made greater use of radiology. Multifactorial analysis demonstrated better survival in the top funding and patient recruitment tertiles (lowest vs. highest (odds ratio & 95% CI: funding 1.050 [1.033–1.068] p<0.0001, recruitment 1.069 [1.052–1.086] p<0.0001), middle vs. highest (funding 1.040 [1.024–1.055] p<0.0001, recruitment 1.085 [1.070–1.100] p<0.0001). Conclusions Research active Trusts appear to have key differences in composition than less research active Trusts. Research active Trusts had lower risk-adjusted mortality for acute admissions, which persisted after adjustment for staffing and other structural factors. PMID:25719608

  4. Hearing outcomes of the active bone conduction system Bonebridge® in conductive or mixed hearing loss.

    PubMed

    Carnevale, Claudio; Til-Pérez, Guillermo; Arancibia-Tagle, Diego J; Tomás-Barberán, Manuel D; Sarría-Echegaray, Pedro L

    2018-05-18

    The active transcutaneous bone conduction implant Bonebridge ® , is indicated for patients affected by bilateral conductive/mixed hearing loss or unilateral sensorineural hearing loss, showing hearing outcomes similar to other percutaneous bone conduction implants, but with a lower rate of complications. The aim of this study was to analyze the hearing outcomes in a series of 26 patients affected by conductive or mixed hearing loss and treated with Bonebridge ® . 26 of 30 patients implanted with Bonebridge ® between October 2012 and May 2017, were included in the study. We compared the air conduction thresholds at the frequencies 500, 1000, 2000, 3000, 4000Hz, the SRT50% and the percentage of correct answers at an intensity of 50dB with and without the implant. "Pure tone average" with the implant was 34.91dB showing an average gain of 33.46dB. Average SRT 50% with the implant was 34.33dB, whereas before the surgery no patient achieved 50% of correct answers at a sound intensity of 50dB. The percentage of correct answers at 50dB changed from 11% without the implant to 85% with it. We only observed one complication consisting of an extrusion of the implant in a patient with a history of 2 previous rhytidectomies. The hearing outcomes obtained in our study are similar to those published in the literature. Bonebridge ® represents an excellent alternative in the treatment of conductive or mixed hearing loss, and with a lower rate of complications. Copyright © 2018 Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello. Publicado por Elsevier España, S.L.U. All rights reserved.

  5. Occupational Safety and Health Activities Conducted across Countries in Asia.

    PubMed

    Park, Jung-Keun; Khai, Ton T

    2015-06-01

    Three occupational safety and health (OSH) activities, one international and two national workshops, were documented as part of OSH activities conducted under the International Labor Organization/Korea Partnership Program in the year 2011-2012. This study aimed to provide information on what the three OSH activities were implemented and how they contributed to the improvement of OSH in Asian countries. The international workshop was useful for the participants to understand a variety of information on OSH as well as participatory action-oriented training (PAOT) approaches at the regional and global levels. The two national workshops were practical for participants to strengthen their knowledge and skills on the PAOT at the enterprise and national levels. The study shows that the three OSH activities contributed to the understanding of the participants on OSH and PAOT, and that the activities promoted the improvement of OSH across countries in Asia.

  6. NASA's Rodent Research Project: Validation of Capabilities for Conducting Long Duration Experiments in Space

    NASA Technical Reports Server (NTRS)

    Choi, Sungshin Y.; Cole, Nicolas; Reyes, America; Lai, San-Huei; Klotz, Rebecca; Beegle, Janet E.; Wigley, Cecilia L.; Pletcher, David; Globus, Ruth K.

    2015-01-01

    Research using rodents is an essential tool for advancing biomedical research on Earth and in space. Prior rodent experiments on the Shuttle were limited by the short flight duration. The International Space Station (ISS) provides a new platform for conducting rodent experiments under long duration conditions. Rodent Research (RR)-1 was conducted to validate flight hardware, operations, and science capabilities that were developed at the NASA Ames Research Center. Twenty C57BL6J adult female mice were launched on Sept 21, 2014 in a Dragon Capsule (SpaceX-4), then transferred to the ISS for a total time of 21-22 days (10 commercial mice) or 37 days (10 validation mice). Tissues collected on-orbit were either rapidly frozen or preserved in RNAlater at -80C (n2group) until their return to Earth. Remaining carcasses on-orbit were rapidly frozen for dissection post-flight. The three controls groups at Kennedy Space Center consisted of: Basal mice euthanized at the time of launch, Vivarium controls housed in standard cages, and Ground Controls (GC) housed in flight hardware within an environmental chamber. Upon return to Earth, there were no differences in body weights between Flight (FLT) and GC at the end of the 37 days in space. Liver enzyme activity levels of FLT mice and all control mice were similar in magnitude to those of the samples that were processed under optimal conditions in the laboratory. Liver samples dissected on-orbit yielded high quality RNA (RIN8.99+-0.59, n7). Liver samples dissected post-flight from the intact, frozen FLT carcasses yielded RIN of 7.27 +- 0.52 (n6). Additionally, wet weights of various tissues were measured. Adrenal glands and spleen showed no significant differences in FLT compared to GC although thymus and livers weights were significantly greater in FLT compared to GC. Over 3,000 tissue aliquots collected post-flight from the four groups of mice were deposited into the Ames Life Science Data Archives for future Biospecimen

  7. Conducting Research with Tribal Communities: Sovereignty, Ethics, and Data-Sharing Issues

    PubMed Central

    Harper, Barbara; Stone, Dave; O’Neill, Catherine; Berger, Patricia; Harris, Stuart; Donatuto, Jamie

    2011-01-01

    Background: When conducting research with American Indian tribes, informed consent beyond conventional institutional review board (IRB) review is needed because of the potential for adverse consequences at a community or governmental level that are unrecognized by academic researchers. Objectives: In this article, we review sovereignty, research ethics, and data-sharing considerations when doing community-based participatory health–related or natural-resource–related research with American Indian nations and present a model material and data-sharing agreement that meets tribal and university requirements. Discussion: Only tribal nations themselves can identify potential adverse outcomes, and they can do this only if they understand the assumptions and methods of the proposed research. Tribes must be truly equal partners in study design, data collection, interpretation, and publication. Advances in protection of intellectual property rights (IPR) are also applicable to IRB reviews, as are principles of sovereignty and indigenous rights, all of which affect data ownership and control. Conclusions: Academic researchers engaged in tribal projects should become familiar with all three areas: sovereignty, ethics and informed consent, and IPR. We recommend developing an agreement with tribal partners that reflects both health-related IRB and natural-resource–related IPR considerations. PMID:21890450

  8. Conducting research with tribal communities: sovereignty, ethics, and data-sharing issues.

    PubMed

    Harding, Anna; Harper, Barbara; Stone, Dave; O'Neill, Catherine; Berger, Patricia; Harris, Stuart; Donatuto, Jamie

    2012-01-01

    When conducting research with American Indian tribes, informed consent beyond conventional institutional review board (IRB) review is needed because of the potential for adverse consequences at a community or governmental level that are unrecognized by academic researchers. In this article, we review sovereignty, research ethics, and data-sharing considerations when doing community-based participatory health-related or natural-resource-related research with American Indian nations and present a model material and data-sharing agreement that meets tribal and university requirements. Only tribal nations themselves can identify potential adverse outcomes, and they can do this only if they understand the assumptions and methods of the proposed research. Tribes must be truly equal partners in study design, data collection, interpretation, and publication. Advances in protection of intellectual property rights (IPR) are also applicable to IRB reviews, as are principles of sovereignty and indigenous rights, all of which affect data ownership and control. Academic researchers engaged in tribal projects should become familiar with all three areas: sovereignty, ethics and informed consent, and IPR. We recommend developing an agreement with tribal partners that reflects both health-related IRB and natural-resource-related IPR considerations.

  9. Psychological research online: report of Board of Scientific Affairs' Advisory Group on the Conduct of Research on the Internet.

    PubMed

    Kraut, Robert; Olson, Judith; Banaji, Mahzarin; Bruckman, Amy; Cohen, Jeffrey; Couper, Mick

    2004-01-01

    As the Internet has changed communication, commerce, and the distribution of information, so too it is changing psychological research. Psychologists can observe new or rare phenomena online and can do research on traditional psychological topics more efficiently, enabling them to expand the scale and scope of their research. Yet these opportunities entail risk both to research quality and to human subjects. Internet research is inherently no more risky than traditional observational, survey, or experimental methods. Yet the risks and safeguards against them will differ from those characterizing traditional research and will themselves change over time. This article describes some benefits and challenges of conducting psychological research via the Internet and offers recommendations to both researchers and institutional review boards for dealing with them. ((c) 2004 APA, all rights reserved) (c) 2004 APA, all rights reserved

  10. 22 CFR 225.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... proposals for research to be conducted or supported by a Federal Department or Agency. 225.120 Section 225... Evaluation and disposition of applications and proposals for research to be conducted or supported by a Federal Department or Agency. The department or agency head will evaluate all applications and proposals...

  11. 15 CFR 27.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... applications and proposals for research to be conducted or supported by a Federal Department or Agency. 27.120... § 27.120 Evaluation and disposition of applications and proposals for research to be conducted or... applications and proposals involving human subjects submitted to the department or agency through such officers...

  12. 16 CFR 1028.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... and proposals for research to be conducted or supported by a Federal Department or Agency. 1028.120... SUBJECTS § 1028.120 Evaluation and disposition of applications and proposals for research to be conducted... applications and proposals involving human subjects submitted to the department or agency through such officers...

  13. 28 CFR 46.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... applications and proposals for research to be conducted or supported by a Federal Department or Agency. 46.120....120 Evaluation and disposition of applications and proposals for research to be conducted or supported... and proposals involving human subjects submitted to the department or agency through such officers and...

  14. Being an Insider Researcher while Conducting Case Study Research

    ERIC Educational Resources Information Center

    Unluer, Sema

    2012-01-01

    It is crucial for social researchers to clarify their researchers' roles, especially for those utilizing qualitative methodology to make their research credible. The purpose of this paper is to examine the advantages and disadvantages of the researcher's insider role, an instructor, occupied within case study research on the integration of…

  15. Shaking stack model of ion conduction through the Ca(2+)-activated K+ channel.

    PubMed Central

    Schumaker, M F

    1992-01-01

    Motivated by the results of Neyton and Miller (1988. J. Gen. Physiol. 92:549-586), suggesting that the Ca(2+)-activated K+ channel has four high affinity ion binding sites, we propose a physically attractive variant of the single-vacancy conduction mechanism for this channel. Simple analytical expressions for conductance, current, flux ratio exponent, and reversal potential under bi-ionic conditions are found. A set of conductance data are analyzed to determine a realistic range of parameter values. Using these, we find qualitative agreement with a variety of experimental results previously reported in the literature. The exquisite selectivity of the Ca(2+)-activated K+ channel may be explained as a consequence of the concerted motion of the "stack" in the proposed mechanism. PMID:1420923

  16. Conducting-polymer-driven actively shaped propellers and screws

    NASA Astrophysics Data System (ADS)

    Madden, John D.; Schmid, Bryan; Lafontaine, Serge R.; Madden, Peter G. A.; Hover, Franz S.; McLetchie, Karl; Hunter, Ian W.

    2003-07-01

    Conducting polymer actuators are employed to create actively shaped hydrodynamic foils. The active foils are designed to allow control over camber, much like the ailerons of an airplane wing. Control of camber promises to enable variable thrust in propellers and screws, increased maneuverability, and improved stealth. The design and fabrication of the active foils are presented, the forces are measured and operation is demonstrated both in still air and water. The foils have a "wing" span of 240 mm, and an average chord length (width) of 70 mm. The trailing 30 mm of the foil is composed of a thin polypyrrole actuator that curls chordwise to achieve variable camber. The actuator consists of two 30 μm thick sheets of hexafluorophosphate doped polypyrrole separated from each other by a gel electrolyte. A polymer layer encapsulates the entire structure. Potentials are applied between the polymer layers to induce reversible bending by approximately 35 degrees, and generating forces of 0.15 N. These forces and displacements are expected to enable operation in water at flow rates of > 1 m/s and ~ 30 m/s in air.

  17. Translating active living research into policy and practice: one important pathway to chronic disease prevention.

    PubMed

    Giles-Corti, Billie; Sallis, James F; Sugiyama, Takemi; Frank, Lawrence D; Lowe, Melanie; Owen, Neville

    2015-05-01

    Global concerns about rising levels of chronic disease make timely translation of research into policy and practice a priority. There is a need to tackle common risk factors: tobacco use, unhealthy diets, physical inactivity, and harmful alcohol use. Using evidence to inform policy and practice is challenging, often hampered by a poor fit between academic research and the needs of policymakers and practitioners--notably for active living researchers whose objective is to increase population physical activity by changing the ways cities are designed and built. We propose 10 strategies that may facilitate translation of research into health-enhancing urban planning policy. Strategies include interdisciplinary research teams of policymakers and practitioners; undertaking explicitly policy-relevant research; adopting appropriate study designs and methodologies (evaluation of policy initiatives as 'natural experiments'); and adopting dissemination strategies that include knowledge brokers, advocates, and lobbyists. Conducting more policy-relevant research will require training for researchers as well as different rewards in academia.

  18. Which nerve conduction parameters can predict spontaneous electromyographic activity in carpal tunnel syndrome?

    PubMed

    Chang, Chia-Wei; Lee, Wei-Ju; Liao, Yi-Chu; Chang, Ming-Hong

    2013-11-01

    We investigate electrodiagnostic markers to determine which parameters are the best predictors of spontaneous electromyographic (EMG) activity in carpal tunnel syndrome (CTS). We enrolled 229 patients with clinically proven and nerve conduction study (NCS)-proven CTS, as well as 100 normal control subjects. All subjects were evaluated using electrodiagnostic techniques, including median distal sensory latencies (DSLs), sensory nerve action potentials (SNAPs), distal motor latencies (DMLs), compound muscle action potentials (CMAPs), forearm median nerve conduction velocities (FMCVs) and wrist-palm motor conduction velocities (W-P MCVs). All CTS patients underwent EMG examination of the abductor pollicis brevis (APB) muscle, and the presence or absence of spontaneous EMG activities was recorded. Normal limits were determined by calculating the means ± 2 standard deviations from the control data. Associations between parameters from the NCS and EMG findings were investigated. In patients with clinically diagnosed CTS, abnormal median CMAP amplitudes were the best predictors of spontaneous activity during EMG examination (p<0.001; OR 36.58; 95% CI 15.85-84.43). If the median CMAP amplitude was ≤ 2.1 mV, the rate of occurrence of spontaneous EMG activity was >95% (positive predictive rate >95%). If the median CMAP amplitude was higher than the normal limit (>4.9 mV), the rate of no spontaneous EMG activity was >94% (negative predictive rate >94%). An abnormal SNAP amplitude was the second best predictor of spontaneous EMG activity (p<0.001; OR 4.13; 95% CI 2.16-7.90), and an abnormal FMCV was the third best predictor (p=0.01; OR 2.10; 95% CI 1.20-3.67). No other nerve conduction parameters had significant power to predict spontaneous activity upon EMG examination. The CMAP amplitudes of the APB are the most powerful predictors of the occurrence of spontaneous EMG activity. Low CMAP amplitudes are strongly associated with spontaneous activity, whereas high CMAP

  19. Rigour and Complexity in Educational Research. Conducting Educational Research

    ERIC Educational Resources Information Center

    Berry, Kathleen; Kincheloe, Joe

    2004-01-01

    What does it mean to engage in rigorous research? What does a researcher need to know to produce such research? What is specifically involved in multiple method bricolage research? In an era where talk abounds about scientific rigour and evidence-based research in education, this groundbreaking book presents a new and compelling examination of…

  20. Development of a Survey Instrument to Measure TEFL Academics' Perceptions about, Individual and Workplace Characteristics for Conducting Research

    ERIC Educational Resources Information Center

    Bai, Li; Hudson, Peter; Millwater, Jan; Tones, Megan

    2013-01-01

    A 30-item survey was devised to determine Chinese TEFL (Teaching English as a Foreign Language) academics' potential for conducting research. A five-part Likert scale was used to gather data from 182 academics on four factors: (1) perceptions on teaching-research nexus, (2) personal perspectives for conducting research, (3) predispositions for…

  1. New Development in NASA's Rodent Research Hardware for Conducting Long Duration Biomedical and Basic Research in Space

    NASA Technical Reports Server (NTRS)

    Shirazi-Fard, Y.; Choi, S.; Harris, C.; Gong, C.; Beegle, J. E.; Stube, K. C.; Martin, K. J.; Nevitt, R. G.; Globus, R. G.

    2017-01-01

    animals easily. The Rodent Research team has also developed Live Animal Return (LAR) capability, which will be implemented during Rodent Research-5 mission for the first time. The animals will be transported from the Habitat to a Transporter, which will return on the Dragon capsule and splashes down in the Pacific Ocean. Once SpaceX retrieves the Dragon, all powered payloads will be transferred to a SeaVan and transferred to the Long Beach pier. The NASA team then receives the transporter and delivers to a PI-designated laboratory within 120 mile radius of Long Beach. This is a significant improvement allowing researchers to examine animals within 72 hrs. of reentry or to conduct recovery experiments. Together, the hardware improvements and experience that the Rodent Research team has gained working with principal investigators and ISS crew to conduct complex experiments on orbit are expanding capabilities for long duration rodent research on the ISS to achieve both basic science and biomedical objectives.

  2. 32 CFR 219.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... proposals for research to be conducted or supported by a Federal Department or Agency. 219.120 Section 219...) MISCELLANEOUS PROTECTION OF HUMAN SUBJECTS § 219.120 Evaluation and disposition of applications and proposals for research to be conducted or supported by a Federal Department or Agency. (a) The department or...

  3. 49 CFR 11.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... proposals for research to be conducted or supported by a Federal Department or Agency. 11.120 Section 11.120... disposition of applications and proposals for research to be conducted or supported by a Federal Department or Agency. The department or agency head will evaluate all applications and proposals involving human...

  4. The Legacy of Hobbs and Gray: Research on the Development and Prevention of Conduct Problems.

    ERIC Educational Resources Information Center

    Dodge, Kenneth A.

    1996-01-01

    Describes research on the development of chronic conduct problems in childhood and adolescence, examining a multiple risk-factor model that includes biological predispositions, ecological context, family processes, peer influences, academic performance, and social information processing as factors leading to conduct problems. The paper describes a…

  5. Conducting HIV research in racial and ethnic minority communities: building a successful interdisciplinary research team.

    PubMed

    Polanco, Frinny R; Dominguez, Dinora C; Grady, Christine; Stoll, Pamela; Ramos, Catalina; Mican, Joann M; Miranda-Acevedo, Robert; Morgan, Marcela; Aizvera, Jeasmine; Purdie, Lori; Koziol, Deloris; Rivera-Goba, Migdalia V

    2011-01-01

    HIV infection occurs in disproportionately high rates among racial and ethnic minorities in the United States, making it imperative that individuals from these groups be included in research studies. However, it is often difficult to recruit HIV-infected Hispanics and African Americans in clinical trials, but a skilled interdisciplinary team that includes researchers with racial and ethnic diversity can help. This article describes a successful approach for building an interdisciplinary team that values the participation of racial and ethnic minorities in clinical trials and has the skills to work with these groups. The success of the Adelante (a Spanish word meaning forward) Team can be attributed to team members who actively participate in decision-making, are empowered, and function in a cohesive manner. Successful research teams build relationships with research participants to increase the probability that racial and ethnic minorities will enroll and participate fully in research. Published by Elsevier Inc.

  6. Issues in Conducting Epidemiologic Research Among Elders: Lessons From The MOBILIZE Boston Study

    PubMed Central

    Kelsey, Jennifer L.; Kiel, Douglas P.; Roman, Anthony M.; Cupples, L. Adrienne; Freeman, Marcie B.; Jones, Richard N.; Hannan, Marian T.; Leveille, Suzanne G.; Gagnon, Margaret M.; Lipsitz, Lewis A.

    2008-01-01

    Conducting research in elderly populations is important, but challenging. In this paper, the authors describe specific challenges that have arisen and solutions that have been used in carrying out The MOBILIZE Boston Study, a community-based, prospective cohort study in Massachusetts focusing on falls among 765 participants aged 70 years or older enrolled during 2005–2007. To recruit older individuals, face-to-face interactions are more effective than less personal approaches. Use of a board of community leaders facilitated community acceptance of the research. Establishing eligibility for potential participants required several interactions, so resources must be anticipated in advance. Assuring a safe and warm environment for elderly participants and offering a positive experience are a vital priority. Adequate funding, planning, and monitoring are required to provide transportation and a fully accessible environment in which to conduct study procedures as well as to select personnel highly skilled in interacting with elders. It is hoped that this paper will encourage and inform future epidemiologic research in this important segment of the population. PMID:18953059

  7. Issues in conducting epidemiologic research among elders: lessons from the MOBILIZE Boston Study.

    PubMed

    Samelson, Elizabeth J; Kelsey, Jennifer L; Kiel, Douglas P; Roman, Anthony M; Cupples, L Adrienne; Freeman, Marcie B; Jones, Richard N; Hannan, Marian T; Leveille, Suzanne G; Gagnon, Margaret M; Lipsitz, Lewis A

    2008-12-15

    Conducting research in elderly populations is important, but challenging. In this paper, the authors describe specific challenges that have arisen and solutions that have been used in carrying out The MOBILIZE Boston Study, a community-based, prospective cohort study in Massachusetts focusing on falls among 765 participants aged 70 years or older enrolled during 2005-2007. To recruit older individuals, face-to-face interactions are more effective than less personal approaches. Use of a board of community leaders facilitated community acceptance of the research. Establishing eligibility for potential participants required several interactions, so resources must be anticipated in advance. Assuring a safe and warm environment for elderly participants and offering a positive experience are a vital priority. Adequate funding, planning, and monitoring are required to provide transportation and a fully accessible environment in which to conduct study procedures as well as to select personnel highly skilled in interacting with elders. It is hoped that this paper will encourage and inform future epidemiologic research in this important segment of the population.

  8. 10 CFR 745.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... applications and proposals for research to be conducted or supported by a Federal department or agency. The... 10 Energy 4 2011-01-01 2011-01-01 false Evaluation and disposition of applications and proposals for research to be conducted or supported by a Federal department or agency. 745.120 Section 745.120...

  9. Building Global Capacity for Conducting Operational Research Using the SORT IT Model: Where and Who?

    PubMed

    Zachariah, Rony; Rust, Stefanie; Berger, Selma Dar; Guillerm, Nathalie; Bissell, Karen; Delaunois, Paul; Reid, Anthony J; Kumar, Ajay M V; Olliaro, Piero L; Reeder, John C; Harries, Anthony D; Ramsay, Andrew

    2016-01-01

    Research capacity is weakest in low and middle-income countries (LMICs) where operational research is highly relevant and needed. Structured Operational Research and Training Initiative (SORT IT) courses have been developed to train participants to conduct and publish operational research and influence policy and practice. Twenty courses were completed in Asia, Africa, Europe and the South Pacific between 2009 and 2014. In the 20 completed SORT IT courses, to assess where the research was conducted, who was trained, who became facilitators in subsequent courses and course outcomes. A cohort study of completed SORT IT courses. There were 236 participants (41% female) including 64 nationalities who conducted research in 59 countries, mostly from Asia and Africa (mean course duration = 9.7 months). Most participants (68%) were from government health programs and non-governmental agencies. A total of 213(90%) participants completed all milestones successfully with 41(19%) becoming subsequent course facilitators, 88% of whom were from LMICs. Of 228 manuscripts submitted to scientific journals, 197(86%) were either published or in press; in 86%, the principal investigator (first author) was a LMIC national. Papers were published in 23 scientific journals (impact factor 0.5-4.4) and covered 21 disease categories (median publication time = 5.7 months). Published papers (186) had 94,794 cumulative article views/downloads. Article views/downloads for immediate open access articles were double those from closed access journals. The SORT IT model has been effective in training personnel to produce relevant operational research in LMICs. It merits continued commitment and support for further scale-up and development.

  10. An institutional approach to support the conduct and use of health policy and systems research: The Nodal Institute in the Eastern Mediterranean Region.

    PubMed

    El-Jardali, Fadi; Saleh, Shadi; Khodor, Rawya; Abu Al Rub, Raeda; Arfa, Chokri; Ben Romdhane, Habiba; Hamadeh, Randah R

    2015-10-01

    The use of health policy and systems research (HPSR) to support decision making in health systems is limited in the Eastern Mediterranean Region (EMR). This is partly due to the lack of effective initiatives to strengthen regional HPSR capacities and promote its use in decision making. This paper offers a structured reflection on the establishment and core functioning of a HPSR Nodal Institute for the EMR with specific focus on the approach used to support the conduct and use of HPSR. It seeks to gain better understanding of the activities conducted by the Nodal Institute, the methods by which the Nodal Institute implemented these activities, and the outcomes of these activities. A multi-faceted approach was implemented by the Nodal Institute in collaboration with regional academic/research institutions, Sub-Nodes. The overall approach was a phased one that included the selection of Sub-Nodes, mapping of academic/research institutions in the EMR, stakeholders' meetings, and HPSR capacity building workshops, and culminated with a regional meeting. The mapping of academic/research institutions in the EMR resulted in the identification of 50 institutions, of which only 32 were engaged in HPSR. These institutions have the highest HPSR involvement in information/evidence (84%) and the lowest in human resources for health (34%). Their main HPSR focus areas included quality of healthcare services, patient safety, management of non-communicable diseases, and human resources for health. Regional HPSR challenges among these institutions were identified. The validation and ranking questionnaires resulted in the identification of country-specific HPSR priorities according to stakeholders in three countries. From these results, cross-cutting HPSR priorities among the countries related to primary healthcare, non-communicable diseases, human resources for health, as well as cross-cutting HPSR priorities among stakeholders and according to stakeholders of the countries, were

  11. A Primer for Conducting Survey Research Using MTurk: Tips for the Field

    ERIC Educational Resources Information Center

    Chambers, Silvana; Nimon, Kim; Anthony-McMann, Paula

    2016-01-01

    This paper presents best practices for conducting survey research using Amazon Mechanical Turk (MTurk). Readers will learn the benefits, limitations, and trade-offs of using MTurk as compared to other recruitment services, including SurveyMonkey and Qualtrics. A synthesis of survey design guidelines along with a sample survey are presented to help…

  12. [An Investigation of the Role Responsibilities of Clinical Research Nurses in Conducting Clinical Trials].

    PubMed

    Kao, Chi-Yin; Huang, Guey-Shiun; Dai, Yu-Tzu; Pai, Ya-Ying; Hu, Wen-Yu

    2015-06-01

    Clinical research nurses (CRNs) play an important role in improving the quality of clinical trials. In Taiwan, the increasing number of clinical trials has increased the number of practicing CRNs. Understanding the role responsibilities of CRNs is necessary to promote professionalism in this nursing category. This study investigates the role responsibilities of CRNs in conducting clinical trials / research. A questionnaire survey was conducted in a medical center in Taipei City, Taiwan. Eighty CRNs that were registered to facilitate and conduct clinical trials at this research site completed the survey. "Subject protection" was the CRN role responsibility most recognized by participants, followed by "research coordination and management", "subject clinical care", and "advanced professional nursing". Higher recognition scores were associated with higher importance scores and lower difficulty scores. Participants with trial training had significantly higher difficulty scores for "subject clinical care" and "research coordination and management" than their peers without this training (p < .05). Participants who had participated in a long-term trial-training course earned higher importance scores for "CRN four-subthemes role responsibilities" (p <.05) and lower difficulty scores for "subject protection", "research coordination and management" (p <.005) than their short-term course peers. "Recognition of overall responsibilities" and "receiving trial training" were the significant predictors of difficulty in performing CRN role responsibilities, explaining 21.9% of the total variance. To further promote CRN as a professional career in Taiwan, the findings of this study recommend identifying the core competences of CRNs and adding CRN-related study materials into the advanced nursing curriculum. Long-term and systematic educational training may help CRNs understand the importance of their role responsibilities, better recognize their professional role, and reflect these

  13. Participants' Reactions to and Suggestions for Conducting Intimate Partner Violence Research: A Study of Rural Young Adults.

    PubMed

    Edwards, Katie M; Greaney, Kayleigh; Palmer, Kelly M

    2016-01-01

    To document rural young adults' reasons for emotional reactions to participating in intimate partner violence (IPV) research as well as to hear young adults' perspectives on how to most effectively conduct comprehensive IPV research in their rural communities. The data presented in this paper draw from 2 studies (ie, an online survey study and an in-person or telephone interview study) that included the same 16 US rural counties in New England and Appalachia. Participants, 47% of whom were in both studies, were young (age range 18-24), white (92%-94%), heterosexual (89%-90%), female (62%-68%), and mostly low to middle income. Nine percent of participants reported they were upset by the questions due to personal experiences with IPV or for other reasons not related to personal IPV experiences. Forty percent of participants reported they personally benefited from participating in the study, and they provided various reasons for this benefit. Regarding suggestions for conducting IPV research with rural young adults, participants believed that both online recruitment and online data collection methods were the best ways to engage young adults, although many participants suggested that more than 1 modality was ideal, which underscores the need for multimethod approaches when conducting research with rural young adults. These findings are reassuring to those committed to conducting research on sensitive topics with rural populations and also shed light on best practices for conducting this type of research from the voices of rural young adults themselves. © 2015 National Rural Health Association.

  14. Overcoming Practical Challenges to Conducting Clinical Research in the Inpatient Stroke Rehabilitation Setting

    PubMed Central

    Campbell, Grace B.; Skidmore, Elizabeth R.; Whyte, Ellen M.; Matthews, Judith T.

    2015-01-01

    There is a shortage of published empirical studies conducted in acute inpatient stroke rehabilitation, though such studies are greatly needed in order to shed light on the most efficacious inpatient stroke rehabilitation interventions. The inherent challenges of inpatient research may dissuade researchers from undertaking this important work. This paper describes our institution’s experience devising practical solutions to research barriers in this setting. Our efforts facilitated five simultaneous inpatient stroke rehabilitation studies, and led to several benefits, including increased effectiveness of research participant identification and enrollment, novel collaborative projects, innovative clinical care initiatives, and enhanced emotional and practical support for patients and their families. We provide recommendations based on lessons learned during our experience, and discuss benefits of this collaboration for our research participants, clinical staff, and the research team. PMID:25775955

  15. Conducting HIV Research in Racial and Ethnic Minority Communities: Building a Successful Interdisciplinary Research Team

    PubMed Central

    Polanco, Frinny R.; Dominguez, Dinora C.; Grady, Christine; Stoll, Pamela; Ramos, Catalina; Mican, JoAnn M.; Miranda-Acevedo, Robert; Morgan, Marcela; Aizvera, Jeasmine; Purdie, Lori; Koziol, Deloris; Rivera-Goba, Migdalia V.

    2011-01-01

    HIV infection occurs in disproportionately high rates among racial and ethnic minorities in the United States, making it imperative that individuals from these groups be included in research studies. Unfortunately, it is often difficult to recruit HIV-infected Hispanics and African Americans into clinical trials, but a skilled interdisciplinary team that includes researchers with racial and ethnic diversity can help. This article describes a successful approach for building an interdisciplinary team that values the participation of racial and ethnic minorities in clinical trials and that has the skills to work with these groups. The success of the Adelante (a Spanish word meaning forward) Team can be attributed to team members who actively participate in decision-making, are empowered, and function in a cohesive manner. Successful research teams build relationships with research participants in order to increase the probability that racial and ethnic minorities will enroll and participate fully in research. PMID:21277228

  16. NASA Langley Research Center's Contributions to International Active Buffeting Alleviation Programs

    NASA Technical Reports Server (NTRS)

    Moses, Robert W.

    2000-01-01

    Buffeting is an aeroelastic phenomenon which plagues high performance aircraft, especially those with twin vertical tails like the F/A-18, at high angles of attack. This buffeting is a concern from fatigue and inspection points of view. By means of wind-tunnel and flight tests, this phenomenon is well studied to the point that buffet loads can be estimated and fatigue life can be increased by structural enhancements to the airframe. In more recent years, buffeting alleviation through active control of smart materials has been highly researched in wind-tunnel proof-of-concept demonstrations and full-scale ground tests using the F/A-18 as a test bed. Because the F/A-18 resides in fleets outside as well as inside the United States, these tests have evolved into international collaborative research activities with Australia and Canada, coordinated by the Air Force Research Laboratory (AFRL) and conducted under the auspices of The Technical Cooperation Program (TTCP). With the recent successes and advances in smart materials, the main focus of these buffeting alleviation tests has also evolved to a new level: utilize the F/A-18 as a prototype to mature smart materials for suppressing vibrations of aerospace structures. The role of the NASA Langley Research Center (LaRC) in these programs is presented.

  17. Enhancement of methanogenesis via direct interspecies electron transfer between Geobacteraceae and Methanosaetaceae conducted by granular activated carbon.

    PubMed

    Zhang, Shuo; Chang, Jiali; Lin, Chao; Pan, Yiran; Cui, Kangping; Zhang, Xiaoyuan; Liang, Peng; Huang, Xia

    2017-12-01

    To understand how granular activated carbon (GAC) promotes methanogenesis, batch tests of CH 4 production potential in anaerobic serum bottles with addition of GAC or not were conducted. Tests showed that GAC promoted methanogenesis remarkably, but the non-conductive zeolite did not. The qPCR demonstrated that the biomass on GAC contributed little to the promotion. High-throughput sequencing data implied that promotion was related with direct interspecies electron transfer between Geobacteraceae and Methanosaetaceae. According to the c-type cytochromes (c-Cyts) response to the supplement of GAC, it was speculated that GAC may play the role of c-Cyts' substitution. In the undefined cultures, the phenomenon that c-Cyts were repressed by GAC was first observed. This research provided new evidence to microbial mechanism of promoting methanogenesis via GAC. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Research and Development. Laboratory Activities.

    ERIC Educational Resources Information Center

    Gallaway, Ann, Ed.

    Research and Development is a laboratory-oriented course that includes the appropriate common essential elements for industrial technology education plus concepts and skills related to research and development. This guide provides teachers of the course with learning activities for secondary students. Introductory materials include an…

  19. 20 CFR 401.165 - Statistical and research activities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Statistical and research activities. 401.165... RECORDS AND INFORMATION Disclosure of Official Records and Information § 401.165 Statistical and research activities. (a) General. Statistical and research activities often do not require information in a format...

  20. 20 CFR 401.165 - Statistical and research activities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Statistical and research activities. 401.165... RECORDS AND INFORMATION Disclosure of Official Records and Information § 401.165 Statistical and research activities. (a) General. Statistical and research activities often do not require information in a format...

  1. 20 CFR 401.165 - Statistical and research activities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Statistical and research activities. 401.165... RECORDS AND INFORMATION Disclosure of Official Records and Information § 401.165 Statistical and research activities. (a) General. Statistical and research activities often do not require information in a format...

  2. Building Global Capacity for Conducting Operational Research Using the SORT IT Model: Where and Who?

    PubMed Central

    Zachariah, Rony; Rust, Stefanie; Berger, Selma Dar; Guillerm, Nathalie; Bissell, Karen; Delaunois, Paul; Reid, Anthony J.; Kumar, Ajay M. V.; Olliaro, Piero L.; Reeder, John C.; Harries, Anthony D.; Ramsay, Andrew

    2016-01-01

    Setting Research capacity is weakest in low and middle-income countries (LMICs) where operational research is highly relevant and needed. Structured Operational Research and Training Initiative (SORT IT) courses have been developed to train participants to conduct and publish operational research and influence policy and practice. Twenty courses were completed in Asia, Africa, Europe and the South Pacific between 2009 and 2014. Objectives In the 20 completed SORT IT courses, to assess where the research was conducted, who was trained, who became facilitators in subsequent courses and course outcomes. Design A cohort study of completed SORT IT courses Results There were 236 participants (41% female) including 64 nationalities who conducted research in 59 countries, mostly from Asia and Africa (mean course duration = 9.7 months). Most participants (68%) were from government health programs and non-governmental agencies. A total of 213(90%) participants completed all milestones successfully with 41(19%) becoming subsequent course facilitators, 88% of whom were from LMICs. Of 228 manuscripts submitted to scientific journals, 197(86%) were either published or in press; in 86%, the principal investigator (first author) was a LMIC national. Papers were published in 23 scientific journals (impact factor 0.5–4.4) and covered 21 disease categories (median publication time = 5.7 months). Published papers (186) had 94,794 cumulative article views/downloads. Article views/downloads for immediate open access articles were double those from closed access journals. Conclusion The SORT IT model has been effective in training personnel to produce relevant operational research in LMICs. It merits continued commitment and support for further scale-up and development. PMID:27505253

  3. Responsible conduct of research in communication sciences and disorders: faculty and student perceptions.

    PubMed

    Minifie, Fred D; Robey, Randall R; Horner, Jennifer; Ingham, Janis C; Lansing, Charissa; McCartney, James H; Alldredge, Elham-Eid; Slater, Sarah C; Moss, Sharon E

    2011-02-01

    Two Web-based surveys (Surveys I and II) were used to assess perceptions of faculty and students in Communication Sciences and Disorders (CSD) regarding the responsible conduct of research (RCR). Survey questions addressed 9 RCR domains thought important to the responsible conduct of research: (a) human subjects protections; (b) research involving animals; (c) publication practices and responsible authorship; (d) mentor/trainee responsibilities; (e) collaborative science; (f) peer review; (g) data acquisition, management, sharing, and ownership; (h) conflicts of interest; and (i) research misconduct. Respondents rated each of 37 topics for importance and for sufficiency of instructional coverage. Respondents to Survey I were 137 faculty members from 68 (26%) of the 261 graduate programs in CSD. By comparison, 237 students from 39 (15%) programs responded to Survey II. Data about the importance and sufficiency of coverage of each of the 37 items were transformed into z scores to reveal relative ratings among the 37 topics. Data presentations were grouped for topics in each of the 9 RCR domains. Ratings indicated the relatively high importance assigned among the 37 topics by CSD faculty and students. Sufficiency of coverage of those same topics received lower ratings. The results of these surveys support the notion that students in CSD perceive that they are receiving information about RCR. The data pertaining to sufficiency of coverage provide a basis for improving instruction in this important aspect of research education.

  4. Engaging families in physical activity research: a family-based focus group study.

    PubMed

    Brown, Helen Elizabeth; Schiff, Annie; van Sluijs, Esther M F

    2015-11-25

    Family-based interventions present a much-needed opportunity to increase children's physical activity levels. However, little is known about how best to engage parents and their children in physical activity research. This study aimed to engage with the whole family to understand how best to recruit for, and retain participation in, physical activity research. Families (including a 'target' child aged between 8 and 11 years, their parents, siblings, and others) were recruited through schools and community groups. Focus groups were conducted using a semi-structured approach (informed by a pilot session). Families were asked to order cards listing the possible benefits of, and the barriers to, being involved in physical activity research and other health promotion activities, highlighting the items they consider most relevant, and suggesting additional items. Duplicate content analysis was used to identify transcript themes and develop a coding frame. Eighty-two participants from 17 families participated, including 17 'target' children (mean age 9.3 ± 1.1 years, 61.1% female), 32 other children and 33 adults (including parents, grandparents, and older siblings). Social, health and educational benefits were cited as being key incentives for involvement in physical activity research, with emphasis on children experiencing new things, developing character, and increasing social contact (particularly for shy children). Children's enjoyment was also given priority. The provision of child care or financial reward was not considered sufficiently appealing. Increased time commitment or scheduling difficulties were quoted as the most pertinent barriers to involvement (especially for families with several children), but parents commented these could be overcome if the potential value for children was clear. Lessons learned from this work may contribute to the development of effective recruitment and retention strategies for children and their families. Making the wide

  5. Matching software practitioner needs to researcher activities

    NASA Technical Reports Server (NTRS)

    Feather, M. S.; Menzies, T.; Connelly, J. R.

    2003-01-01

    We present an approach to matching software practitioners' needs to software researchers' activities. It uses an accepted taxonomical software classfication scheme as intermediary, in terms of which practitioners express needs, and researchers express activities.

  6. Ethical Considerations in Conducting Research on Autism Spectrum Disorders in Low and Middle Income Countries

    ERIC Educational Resources Information Center

    Daley, Tamara C.; Singhal, Nidhi; Krishnamurthy, Vibha

    2013-01-01

    Autism spectrum disorder (ASD) is being identified in an ever-increasing number of countries, including many that are low or middle income (LMIC). Research conducted in these countries requires awareness of unique ethical issues. Drawing on the experience of two organizations that have been involved in conducting and collaborating in ASD research…

  7. Preparing Practitioners to Conduct Educational Research and Evaluation: What the Research Says and What Our Experiences Taught Us

    ERIC Educational Resources Information Center

    Mansfield, Katherine Cumings; Stacy, Jaime

    2017-01-01

    The purpose of this article is to share the insights gleaned from the literature and our on-the-ground realities teaching practitioners to conduct educational research and evaluation. We focus on four areas we have found most important for teaching practitioner-scholars: (a) giving careful attention to andragogy versus pedagogy, (b) engaging the…

  8. Family intervention in Indigenous communities: emergent issues in conducting outcome research.

    PubMed

    Turner, Karen; Sanders, Matthew

    2007-01-01

    Indigenous children and youth are at greater risk of emotional and behavioural problems than non-Indigenous youth, with family life stresses and parenting style identified as common risk factors. There is substantial evidence that parenting programs can improve family relationships and improve child outcomes, however little research has focused on Indigenous communities. Our team is conducting research to evaluate a culturally sensitive adaptation of a mainstream intervention, the Group Triple P---Positive Parenting Program, for Indigenous families. This paper shares some of the insights into research and clinical issues gained as non-Indigenous researchers working with urban, rural and remote Indigenous communities. The experience of the research team and feedback from practitioners and parents have been drawn on for this discussion. Parenting programs need to be sensitive to the political and cultural context in which parenting takes place, flexibly incorporate cultural practices and expectations, and develop an evidence base of outcomes for families in diverse communities. As research is needed to evaluate the acceptability and effectiveness of these programs, culturally sensitive research practices are also necessary and the value of program evaluation and its benefit to the community must be clear. Community acceptance of the research process and the intervention itself is vital and may be influenced by community perceptions, current priorities, and local issues. If our overall aim is to increase the skilled health and mental health workforce in Indigenous communities and their use of evidence-based interventions, ongoing collaborative relationships between research institutions and service providers will serve to further this aim.

  9. Determining Attitudes of Postgraduate Students towards Scientific Research and Codes of Conduct, Supported by Digital Script

    ERIC Educational Resources Information Center

    Tavukcu, Tahir

    2016-01-01

    In this research, it is aimed to determine the effect of the attitudes of postgraduate students towards scientific research and codes of conduct, supported by digital script. This research is a quantitative study, and it has been formed according to pre-test & post-test research model of experiment and control group. In both groups, lessons…

  10. 76 FR 50457 - Taking and Importing Marine Mammals; Military Training Activities and Research Conducted Within...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-15

    ... were taken for species identification and individual recognition. Surveys conducted around Saipan and... individual recognition. Photo Data Collection and Biopsy Sampling In conjunction with the vessel surveys from... biopsy samples were collected. Photos will be used to study social behavior and movement patterns of...

  11. Conducting a Multisite Education Research Project: Strategies to Overcome the Barriers to Achieve the Benefits.

    PubMed

    Beischel, Kelly P; Hart, Julie; Turkelson, Sandra L

    2016-01-01

    Multisite education research projects have many benefits as well as perceived barriers. In this article, we share our experiences with a multisite education research project and the barriers we overcame to reap the benefits. The outcome of our research resulted in increased rigor, role-modeling professional collaboration, and promotion of future multisite education studies. The strategies presented in this article will help alleviate perceived barriers and ameliorate the process of conducting multisite education research studies.

  12. Cracking the Code: Assessing Institutional Compliance with the Australian Code for the Responsible Conduct of Research

    ERIC Educational Resources Information Center

    Morris, Suzanne E.

    2010-01-01

    This paper provides a review of institutional authorship policies as required by the "Australian Code for the Responsible Conduct of Research" (the "Code") (National Health and Medical Research Council (NHMRC), the Australian Research Council (ARC) & Universities Australia (UA) 2007), and assesses them for Code compliance.…

  13. Mapping Research Activities and Technologies for Sustainability and Environmental Studies--A Case Study at University Level

    ERIC Educational Resources Information Center

    Hara, Keishiro; Uwasu, Michinori; Kurimoto, Shuji; Yamanaka, Shinsuke; Umeda, Yasushi; Shimoda, Yoshiyuki

    2013-01-01

    Systemic understanding of potential research activities and available technology seeds at university level is an essential condition to promote interdisciplinary and vision-driven collaboration in an attempt to cope with complex sustainability and environmental problems. Nonetheless, any such practices have been hardly conducted at universities…

  14. 10 CFR 52.91 - Authorization to conduct limited work authorization activities.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... determination required by 10 CFR 50.10(e), and the Director of New Reactors or the Director of Nuclear Reactor... activities. 52.91 Section 52.91 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.91 Authorization to conduct limited work...

  15. 10 CFR 52.91 - Authorization to conduct limited work authorization activities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... determination required by 10 CFR 50.10(e), and the Director of New Reactors or the Director of Nuclear Reactor... activities. 52.91 Section 52.91 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.91 Authorization to conduct limited work...

  16. 10 CFR 52.91 - Authorization to conduct limited work authorization activities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... determination required by 10 CFR 50.10(e), and the Director of New Reactors or the Director of Nuclear Reactor... activities. 52.91 Section 52.91 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.91 Authorization to conduct limited work...

  17. 10 CFR 52.91 - Authorization to conduct limited work authorization activities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... determination required by 10 CFR 50.10(e), and the Director of New Reactors or the Director of Nuclear Reactor... activities. 52.91 Section 52.91 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.91 Authorization to conduct limited work...

  18. 10 CFR 52.91 - Authorization to conduct limited work authorization activities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... determination required by 10 CFR 50.10(e), and the Director of New Reactors or the Director of Nuclear Reactor... activities. 52.91 Section 52.91 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES, CERTIFICATIONS, AND APPROVALS FOR NUCLEAR POWER PLANTS Combined Licenses § 52.91 Authorization to conduct limited work...

  19. 77 FR 46606 - Enforcement of Nondiscrimination on the Basis of Disability in Programs and Activities Conducted...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-06

    ..., and specific learning disabilities. (3) Diseases and conditions such as orthopedic, visual, speech and... of Nondiscrimination on the Basis of Disability in Programs and Activities Conducted by the Bureau of... disability in programs or activities conducted by the Bureau of Consumer Financial Protection. It sets forth...

  20. Antiviral Drug Research Proposal Activity

    PubMed Central

    Injaian, Lisa; Smith, Ann C.; Shipley, Jennifer German; Marbach-Ad, Gili; Fredericksen, Brenda

    2011-01-01

    The development of antiviral drugs provides an excellent example of how basic and clinical research must be used together in order to achieve the final goal of treating disease. A Research Oriented Learning Activity was designed to help students to better understand how basic and clinical research can be combined toward a common goal. Through this project students gained a better understanding of the process of scientific research and increased their information literacy in the field of virology. The students worked as teams to research the many aspects involved in the antiviral drug design process, with each student becoming an “expert” in one aspect of the project. The Antiviral Drug Research Proposal (ADRP) culminated with students presenting their proposals to their peers and local virologists in a poster session. Assessment data showed increased student awareness and knowledge of the research process and the steps involved in the development of antiviral drugs as a result of this activity. PMID:23653735

  1. The Need to Objectively Measure Physical Activity During Pregnancy: Considerations for Clinical Research and Public Health Impact.

    PubMed

    Guérin, Eva; Ferraro, Zachary M; Adamo, Kristi B; Prud'homme, Denis

    2018-05-01

    Engaging in recommended levels of physical activity during pregnancy can provide a host of physical and mental health benefits for the expecting mother and her child. However, methodological issues related to physical activity measurement have plagued many studies examining the effects of physical activity during this important life stage. Burgeoning support exists for the more widespread use of objective methods, and accelerometers specifically, for an accurate appraisal of maternal physical activity. In this commentary, we highlight discrepancies between activity estimates obtained via self-report and objective measures and describe the implications of erroneous measurement when making clinical recommendations and in conducting future physical activity and pregnancy research. Most importantly, we aim to foster academic discussion and propose a call to action requiring a paradigm shift where we acknowledge the shortcomings of self-report and move toward an empirically driven approach for physical activity measurement. Results from more high-quality research studies will help support public health messaging and facilitate trust among health care providers, clinical researchers, and expecting mothers regarding the health benefits of physical activity recommendations.

  2. Responsible Conduct of Research Assessment of Doctor of Education Candidates, Graduate Faculty, and Curriculum Considerations

    ERIC Educational Resources Information Center

    Thompson, Carla J.

    2014-01-01

    The study included an assessment of doctoral students, graduate faculty, and curriculum considerations to determine the degree of infusion of research integrity and responsible conduct of research (RCR) principles within a Doctor of Education program. Study results showed substantial increases in doctoral candidates' knowledge levels of RCR,…

  3. 45 CFR 46.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Assuring compliance with this policy-research conducted or supported by any Federal Department or Agency. 46.103 Section 46.103 Public Welfare DEPARTMENT... welfare of human subjects of research conducted at or sponsored by the institution, regardless of whether...

  4. 45 CFR 46.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Assuring compliance with this policy-research conducted or supported by any Federal Department or Agency. 46.103 Section 46.103 Public Welfare DEPARTMENT... welfare of human subjects of research conducted at or sponsored by the institution, regardless of whether...

  5. 45 CFR 46.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Assuring compliance with this policy-research conducted or supported by any Federal Department or Agency. 46.103 Section 46.103 Public Welfare DEPARTMENT... welfare of human subjects of research conducted at or sponsored by the institution, regardless of whether...

  6. 45 CFR 46.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Assuring compliance with this policy-research conducted or supported by any Federal Department or Agency. 46.103 Section 46.103 Public Welfare Department... welfare of human subjects of research conducted at or sponsored by the institution, regardless of whether...

  7. 30 CFR 585.800 - How must I conduct my activities to comply with safety and environmental requirements?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... for Activities Conducted Under SAPs, COPs and GAPs § 585.800 How must I conduct my activities to.... (b) You must certify compliance with those terms and conditions identified in your approved SAP, COP...

  8. 30 CFR 585.800 - How must I conduct my activities to comply with safety and environmental requirements?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... for Activities Conducted Under SAPs, COPs and GAPs § 585.800 How must I conduct my activities to.... (b) You must certify compliance with those terms and conditions identified in your approved SAP, COP...

  9. 30 CFR 585.800 - How must I conduct my activities to comply with safety and environmental requirements?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... for Activities Conducted Under SAPs, COPs and GAPs § 585.800 How must I conduct my activities to.... (b) You must certify compliance with those terms and conditions identified in your approved SAP, COP...

  10. Zinc-dependent multi-conductance channel activity in mitochondria isolated from ischemic brain.

    PubMed

    Bonanni, Laura; Chachar, Mushtaque; Jover-Mengual, Teresa; Li, Hongmei; Jones, Adrienne; Yokota, Hidenori; Ofengeim, Dimitry; Flannery, Richard J; Miyawaki, Takahiro; Cho, Chang-Hoon; Polster, Brian M; Pypaert, Marc; Hardwick, J Marie; Sensi, Stefano L; Zukin, R Suzanne; Jonas, Elizabeth A

    2006-06-21

    Transient global ischemia is a neuronal insult that induces delayed cell death. A hallmark event in the early post-ischemic period is enhanced permeability of mitochondrial membranes. The precise mechanisms by which mitochondrial function is disrupted are, as yet, unclear. Here we show that global ischemia promotes alterations in mitochondrial membrane contact points, a rise in intramitochondrial Zn2+, and activation of large, multi-conductance channels in mitochondrial outer membranes by 1 h after insult. Mitochondrial channel activity was associated with enhanced protease activity and proteolytic cleavage of BCL-xL to generate its pro-death counterpart, deltaN-BCL-xL. The findings implicate deltaN-BCL-xL in large, multi-conductance channel activity. Consistent with this, large channel activity was mimicked by introduction of recombinant deltaN-BCL-xL to control mitochondria and blocked by introduction of a functional BCL-xL antibody to post-ischemic mitochondria via the patch pipette. Channel activity was also inhibited by nicotinamide adenine dinucleotide, indicative of a role for the voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane. In vivo administration of the membrane-impermeant Zn2+ chelator CaEDTA before ischemia or in vitro application of the membrane-permeant Zn2+ chelator tetrakis-(2-pyridylmethyl) ethylenediamine attenuated channel activity, suggesting a requirement for Zn2+. These findings reveal a novel mechanism by which ischemic insults disrupt the functional integrity of the outer mitochondrial membrane and implicate deltaN-BCL-xL and VDAC in the large, Zn2+-dependent mitochondrial channels observed in post-ischemic hippocampal mitochondria.

  11. Zinc-Dependent Multi-Conductance Channel Activity in Mitochondria Isolated from Ischemic Brain

    PubMed Central

    Bonanni, Laura; Chachar, Mushtaque; Jover-Mengual, Teresa; Li, Hongmei; Jones, Adrienne; Yokota, Hidenori; Ofengeim, Dimitry; Flannery, Richard J.; Miyawaki, Takahiro; Cho, Chang-Hoon; Polster, Brian M.; Pypaert, Marc; Hardwick, J. Marie; Sensi, Stefano L.; Zukin, R. Suzanne; Jonas, Elizabeth A.

    2015-01-01

    Transient global ischemia is a neuronal insult that induces delayed cell death. A hallmark event in the early post-ischemic period is enhanced permeability of mitochondrial membranes. The precise mechanisms by which mitochondrial function is disrupted are, as yet, unclear.Here we show that global ischemia promotes alterations in mitochondrial membrane contact points, a rise in intramitochondrial Zn2+, and activation of large, multi-conductance channels in mitochondrial outer membranes by 1 h after insult. Mitochondrial channel activity was associated with enhanced protease activity and proteolytic cleavage of BCL-xL to generate its pro-death counterpart, ΔN-BCL-xL. The findings implicate ΔN-BCL-xL in large, multi-conductance channel activity. Consistent with this, large channel activity was mimicked by introduction of recombinant ΔN-BCL-xL to control mitochondria and blocked by introduction of a functional BCL-xL antibody to post-ischemic mitochondria via the patch pipette. Channel activity was also inhibited by nicotinamide adenine dinucleotide, indicative of a role for the voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane. In vivo administration of the membrane-impermeant Zn2+ chelator CaEDTA before ischemia or in vitro application of the membrane-permeant Zn2+ chelator tetrakis-(2-pyridylmethyl) ethylenediamine attenuated channel activity, suggesting a requirement for Zn2+. These findings reveal a novel mechanism by which ischemic insults disrupt the functional integrity of the outer mitochondrial membrane and implicate ΔNBCL-xL and VDAC in the large, Zn2+-dependent mitochondrial channels observed in post-ischemic hippocampal mitochondria. PMID:16793892

  12. Challenges and strategies for conducting sensitive research with an Arab American population.

    PubMed

    Timraz, Shahrazad M; Alhasanat, Dalia I; Albdour, Maha M; Lewin, Linda; Giurgescu, Carmen; Kavanaugh, Karen

    2017-02-01

    Recruiting minority groups such as Arab Americans (Ar-Am) for research studies has been challenging. To date no studies were found that explicitly addressed challenges to recruit Ar-Am for sensitive research. The purpose of this article is to present the challenges across three pilot studies that involved Ar-Am samples and the strategies that were implemented to overcome these challenges. The challenges faced with conducting studies with Ar-Am included difficulty for participants to express emotions, influence of male/female authority to consent for the study, lack of trust to disclose sensitive information, language barrier, and slow recruitment. Having bilingual female recruiters of Arabic descent, engaging the women's family members in the consent process, and addressing the sensitive topics in culturally appropriate language were effective strategies to overcome these challenges. These strategies might be helpful for other researchers who recruit Ar-Am for sensitive research. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. 7 CFR 1c.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... proposals for research to be conducted or supported by a Federal Department or Agency. 1c.120 Section 1c.120... disposition of applications and proposals for research to be conducted or supported by a Federal Department or Agency. (a) The department or agency head will evaluate all applications and proposals involving human...

  14. 21 CFR 20.105 - Testing and research conducted by or with funds provided by the Food and Drug Administration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Testing and research conducted by or with funds... Categories of Records § 20.105 Testing and research conducted by or with funds provided by the Food and Drug Administration. (a) Any list that may be prepared by the Food and Drug Administration of testing and research...

  15. 21 CFR 20.105 - Testing and research conducted by or with funds provided by the Food and Drug Administration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Testing and research conducted by or with funds... Categories of Records § 20.105 Testing and research conducted by or with funds provided by the Food and Drug Administration. (a) Any list that may be prepared by the Food and Drug Administration of testing and research...

  16. Human Research Program Science Management: Overview of Research and Development Activities

    NASA Technical Reports Server (NTRS)

    Charles, John B.

    2007-01-01

    An overview of research and development activities of NASA's Human Research Science Management Program is presented. The topics include: 1) Human Research Program Goals; 2) Elements and Projects within HRP; 3) Development and Maintenance of Priorities; 4) Acquisition and Evaluation of Research and Technology Proposals; and 5) Annual Reviews

  17. NASA SPoRT Modeling and Data Assimilation Research and Transition Activities Using WRF, LIS and GSI

    NASA Technical Reports Server (NTRS)

    Case, Jonathan L.; Blankenship, Clay B.; Zavodsky, Bradley T.; Srikishen, Jayanthi; Berndt, Emily B.

    2014-01-01

    weather research and forecasting ===== The NASA Short-term Prediction Research and Transition (SPoRT) program has numerous modeling and data assimilation (DA) activities in which the WRF model is a key component. SPoRT generates realtime, research satellite products from the MODIS and VIIRS instruments, making the data available to NOAA/NWS partners running the WRF/EMS, including: (1) 2-km northwestern-hemispheric SST composite, (2) daily, MODIS green vegetation fraction (GVF) over CONUS, and (3) NASA Land Information System (LIS) runs of the Noah LSM over the southeastern CONUS. Each of these datasets have been utilized by specific SPoRT partners in local EMS model runs, with select offices evaluating the impacts using a set of automated scripts developed by SPoRT that manage data acquisition and run the NCAR Model Evaluation Tools verification package. SPoRT is engaged in DA research with the Gridpoint Statistical Interpolation (GSI) and Ensemble Kalman Filter in LIS for soil moisture DA. Ongoing DA projects using GSI include comparing the impacts of assimilating Atmospheric Infrared Sounder (AIRS) radiances versus retrieved profiles, and an analysis of extra-tropical cyclones with intense non-convective winds. As part of its Early Adopter activities for the NASA Soil Moisture Active Passive (SMAP) mission, SPoRT is conducting bias correction and soil moisture DA within LIS to improve simulations using the NASA Unified-WRF (NU-WRF) for both the European Space Agency's Soil Moisture Ocean Salinity and upcoming SMAP mission data. SPoRT has also incorporated real-time global GVF data into LIS and WRF from the VIIRS product being developed by NOAA/NESDIS. This poster will highlight the research and transition activities SPoRT conducts using WRF, NU-WRF, EMS, LIS, and GSI.

  18. Conducting Field Research on Gender Relations in a Gender Repressive State: A Case Study of Gender Research in Iran

    ERIC Educational Resources Information Center

    Rezai-Rashti, Goli M.

    2013-01-01

    This paper reflects on the experience of conducting fieldwork and the gendering of research within the context of a gender repressive state. The Islamic Republic of Iran has consistently enacted discriminatory policies regarding gender relations since 1979. These regressive measures have made the state apprehensive and sensitive towards any…

  19. Ask "Teaching Sociology": What Should Faculty Consider before Having Students Conduct Research in a Class?

    ERIC Educational Resources Information Center

    Lowney, Kathleen S.

    2014-01-01

    There are many things that sociology faculty have to consider as they begin planning a student course such as: (1) why students need to understand scientific methods, by conducting research for themselves; (2) What specific learning goals and objectives will be met by students doing research, either individually or collectively?; (3) Why do…

  20. Comparative effectiveness research for the clinician researcher: a framework for making a methodological design choice.

    PubMed

    Williams, Cylie M; Skinner, Elizabeth H; James, Alicia M; Cook, Jill L; McPhail, Steven M; Haines, Terry P

    2016-08-17

    Comparative effectiveness research compares two active forms of treatment or usual care in comparison with usual care with an additional intervention element. These types of study are commonly conducted following a placebo or no active treatment trial. Research designs with a placebo or non-active treatment arm can be challenging for the clinician researcher when conducted within the healthcare environment with patients attending for treatment.A framework for conducting comparative effectiveness research is needed, particularly for interventions for which there are no strong regulatory requirements that must be met prior to their introduction into usual care. We argue for a broader use of comparative effectiveness research to achieve translatable real-world clinical research. These types of research design also affect the rapid uptake of evidence-based clinical practice within the healthcare setting.This framework includes questions to guide the clinician researcher into the most appropriate trial design to measure treatment effect. These questions include consideration given to current treatment provision during usual care, known treatment effectiveness, side effects of treatments, economic impact, and the setting in which the research is being undertaken.

  1. 42 CFR 2.52 - Research activities.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Research activities. 2.52 Section 2.52 Public... OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures Without Patient Consent § 2.52 Research... research if the program director makes a determination that the recipient of the patient identifying...

  2. 42 CFR 2.52 - Research activities.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Research activities. 2.52 Section 2.52 Public... OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures Without Patient Consent § 2.52 Research... research if the program director makes a determination that the recipient of the patient identifying...

  3. 42 CFR 2.52 - Research activities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Research activities. 2.52 Section 2.52 Public... OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures Without Patient Consent § 2.52 Research... research if the program director makes a determination that the recipient of the patient identifying...

  4. 42 CFR 2.52 - Research activities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Research activities. 2.52 Section 2.52 Public... OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures Without Patient Consent § 2.52 Research... research if the program director makes a determination that the recipient of the patient identifying...

  5. 42 CFR 2.52 - Research activities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Research activities. 2.52 Section 2.52 Public... OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Disclosures Without Patient Consent § 2.52 Research... research if the program director makes a determination that the recipient of the patient identifying...

  6. Up-Regulatory Effects of Curcumin on Large Conductance Ca2+-Activated K+ Channels

    PubMed Central

    Hei, Hongya; Li, Fangping; Wang, Yunman; Peng, Wen; Zhang, Xuemei

    2015-01-01

    Large conductance Ca2+-activated potassium channels (BK) are targets for research that explores therapeutic means to various diseases, owing to the roles of the channels in mediating multiple physiological processes in various cells and tissues. We investigated the pharmacological effects of curcumin, a compound isolated from the herb Curcuma longa, on BK channels. As recorded by whole-cell patch-clamp, curcumin increased BK (α) and BK (α+β1) currents in transfected HEK293 cells as well as the current density of BK in A7r5 smooth muscle cells in a dose-dependent manner. By incubating with curcumin for 24 hours, the current density of exogenous BK (α) in HEK293 cells and the endogenous BK in A7r5 cells were both enhanced notably, though the steady-state activation of the channels did not shift significantly, except for BK (α+β1). Curcumin up-regulated the BK protein expression without changing its mRNA level in A7r5 cells. The surface expression and the half-life of BK channels were also increased by curcumin in HEK293 cells. These effects of curcumin were abolished by MG-132, a proteasome inhibitor. Curcumin also increased ERK 1/2 phosphorylation, while inhibiting ERK by U0126 attenuated the curcumin-induced up-regulation of BK protein expression. We also observed that the curcumin-induced relaxation in the isolated rat aortic rings was significantly attenuated by paxilline, a BK channel specific blocker. These results show that curcumin enhances the activity of the BK channels by interacting with BK directly as well as enhancing BK protein expression through inhibiting proteasomal degradation and activating ERK signaling pathway. The findings suggest that curcumin is a potential BK channel activator and provide novel insight into its complicated pharmacological effects and the underlying mechanisms. PMID:26672753

  7. Transparent electrical conducting films by activated reactive evaporation

    DOEpatents

    Bunshah, Rointan; Nath, Prem

    1982-01-01

    Process and apparatus for producing transparent electrical conducting thin films by activated reactive evaporation. Thin films of low melting point metals and alloys, such as indium oxide and indium oxide doped with tin, are produced by physical vapor deposition. The metal or alloy is vaporized by electrical resistance heating in a vacuum chamber, oxygen and an inert gas such as argon are introduced into the chamber, and vapor and gas are ionized by a beam of low energy electrons in a reaction zone between the resistance heater and the substrate. There is a reaction between the ionized oxygen and the metal vapor resulting in the metal oxide which deposits on the substrate as a thin film which is ready for use without requiring post deposition heat treatment.

  8. Electrically Conductive and Optically Active Porous Silicon Nanowires

    PubMed Central

    Qu, Yongquan; Liao, Lei; Li, Yujing; Zhang, Hua; Huang, Yu; Duan, Xiangfeng

    2009-01-01

    We report the synthesis of vertical silicon nanowire array through a two-step metal-assisted chemical etching of highly doped n-type silicon (100) wafers in a solution of hydrofluoric acid and hydrogen peroxide. The morphology of the as-grown silicon nanowires is tunable from solid nonporous nanowires, nonporous/nanoporous core/shell nanowires, and entirely nanoporous nanowires by controlling the hydrogen peroxide concentration in the etching solution. The porous silicon nanowires retain the single crystalline structure and crystallographic orientation of the starting silicon wafer, and are electrically conductive and optically active with visible photoluminescence. The combination of electronic and optical properties in the porous silicon nanowires may provide a platform for the novel optoelectronic devices for energy harvesting, conversion and biosensing. PMID:19807130

  9. Local conduction during acute myocardial infarction in rats: Interplay between central sympathetic activation and endothelin.

    PubMed

    Kolettis, Theofilos M; Kontonika, Marianthi; La Rocca, Vassilios; Vlahos, Antonios P; Baltogiannis, Giannis G; Kyriakides, Zenon S

    2017-04-01

    We investigated the effects of autonomic dysfunction and endothelin on local conduction and arrhythmogenesis during myocardial infarction. We recorded ventricular tachyarrhythmias, monophasic action potentials, and activation sequences in wild-type and ET B -deficient rats displaying high endothelin levels. Central sympathetic inputs were examined after clonidine administration. Clonidine mitigated early and delayed arrhythmogenesis in ET B -deficient and wild-type rats, respectively. The right ventricular activation delay increased in clonidine-treated ET B -deficient rats and slightly decreased in wild-type rats. The left ventricular voltage rise decreased in all groups, whereas the activation delay increased mainly in clonidine-treated ET B -deficient rats. Central sympathetic activation and endothelin modulate ischemia-induced arrhythmogenesis. Ischemia alters excitability, whereas endothelin impairs local conduction, an action partly counterbalanced by central sympathetic activity.

  10. Contributions to Active Buffeting Alleviation Programs by the NASA Langley Research Center

    NASA Technical Reports Server (NTRS)

    Moses, Robert W.

    1999-01-01

    Buffeting is an aeroelastic phenomenon which plagues high performance aircraft, especially those with twin vertical tails like the F/A-18, at high angles of attack. This buffeting is a concern from fatigue and inspection points of view. By means of wind-tunnel and flight tests, this phenomenon is well studied to the point that buffet loads can be estimated and fatigue life can be increased by structural enhancements to the airframe. In more recent years, buffeting alleviation through active control of smart materials has been highly researched in wind-tunnel proof-of-concept demonstrations and full-scale ground tests using the F/A-18 as a test bed. Because the F/A-18 resides in fleets outside as well as inside the United States, these tests have evolved into international collaborative research activities with Australia and Canada, coordinated by the Air Force Research Laboratory (AFRL) and conducted under the auspices of The Technical Cooperation Program (TTCP). With the recent successes and advances in smart materials, the main focus of these buffeting alleviation tests has also evolved to a new level: utilize the F/A-18 as a prototype to mature smart materials for suppressing vibrations of aerospace structures. The role of the NASA Langley Research Center (LaRC) in these programs is presented.

  11. The examination of headache activity using time-series research designs.

    PubMed

    Houle, Timothy T; Remble, Thomas A; Houle, Thomas A

    2005-05-01

    The majority of research conducted on headache has utilized cross-sectional designs which preclude the examination of dynamic factors and principally rely on group-level effects. The present article describes the application of an individual-oriented process model using time-series analytical techniques. The blending of a time-series approach with an interactive process model allows consideration of the relationships of intra-individual dynamic processes, while not precluding the researcher to examine inter-individual differences. The authors explore the nature of time-series data and present two necessary assumptions underlying the time-series approach. The concept of shock and its contribution to headache activity is also presented. The time-series approach is not without its problems and two such problems are specifically reported: autocorrelation and the distribution of daily observations. The article concludes with the presentation of several analytical techniques suited to examine the time-series interactive process model.

  12. Education in the responsible conduct of research in psychology: methods and scope.

    PubMed

    DiLorenzo, Terry A; Becker-Fiegeles, Jill; Gibelman, Margaret

    2014-01-01

    In this mixed-method study of education in the responsible conduct of research (RCR) in psychology, phase one survey respondents (n = 141) reported that faculty and students were familiar with RCR standards and procedures to educate them were believed to be adequate. However, educational methods varied widely. In phase two, seven survey respondents completed in-depth interviews assessing RCR training and education and research review procedures. Educational methods through which RCR content was presented included the following ones: traditional (lectures), technical (web-based), and experiential (internships), but RCR was often minimally considered in the formal curriculum. Our results suggest that psychology training programs might benefit from more formal consideration of RCR education and training in the curriculum.

  13. Balancing activity, stability and conductivity of nanoporous core-shell iridium/iridium oxide oxygen evolution catalysts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Yong-Tae; Lopes, Pietro Papa; Park, Shin-Ae

    The selection of oxide materials for catalyzing the Oxygen Evolution Reaction in acid-based electrolyzers must be guided by the proper balance between activity, stability and conductivity – a challenging mission of great importance for delivering affordable and environmentally friendly hydrogen. Here we report that the highly conductive nanoporous architecture of an iridium oxide shell on a metallic iridium core, formed through the fast dealloying of osmium from an Ir25Os75 alloy, exhibits an exceptional balance between oxygen evolution activity and stability as quantified by the Activity-Stability FactorASF. Based on this metric, the nanoporous Ir/IrO2 morphology of dealloyed Ir25Os75 shows a factormore » of ~30 improvement ASFrelative to conventional Ir-based oxide materials and a ~8 times improvement over dealloyed Ir25Os75 nanoparticles due to optimized stability and conductivity, respectively. We propose that the Activity-Stability FactorASF is the key “metric” for determining the technological relevance of oxide-based anodic water electrolyzer catalysts.« less

  14. Conducting Clinically Based Intimate Partner Violence Research: Safety Protocol Recommendations.

    PubMed

    Anderson, Jocelyn C; Glass, Nancy E; Campbell, Jacquelyn C

    Maintaining safety is of utmost importance during research involving participants who have experienced intimate partner violence (IPV). Limited guidance on safety protocols to protect participants is available, particularly information related to technology-based approaches to informed consent, data collection, and contacting participants during the course of a study. The purpose of the article is to provide details on the safety protocol developed and utilized with women receiving care at an urban HIV clinic and who were taking part in an observational study of IPV, mental health symptoms, and substance abuse and their relationship to HIV treatment adherence. The protocol presents the technological strategies to promote safety and allow autonomy in participant decision-making throughout the research process, including Voice over Internet Protocol telephone numbers, and tablet-based eligibility screening and data collection. Protocols for management of participants at risk for suicide and/or intimate partner homicide that included automated high-risk messaging to participants and research staff and facilitated disclosure of risk to clinical staff based on participant preferences are discussed. Use of technology and partnership with clinic staff helped to provide an environment where research regarding IPV could be conducted without undue burden or risk to participants. Utilizing tablet-based survey administration provided multiple practical and safety benefits for participants. Most women who screened into high-risk categories for suicide or intimate partner homicide did not choose to have their results shared with their healthcare providers, indicating the importance of allowing participants control over information sharing whenever possible.

  15. 2nd Annual Postdoc Research Day: US Army Research Laboratory PosterSymposia and Activities

    DTIC Science & Technology

    2018-04-12

    ARL-SR-0394•APR 2018 US Army Research Laboratory 2nd Annual Postdoc Research Day: US Army Research Laboratory Poster Symposia and Activities by...Do not return it to the originator. ARL-SR-0394•APR 2018 US Army Research Laboratory 2nd Annual Postdoc Research Day: US Army Research Laboratory...Poster Symposia and Activities by Efraín Hernández–Rivera Weapons and Materials Research Directorate, ARL Julia Cline Oak Ridge Institute for Science and

  16. The conduct of practice-based research in community clinics compared to private practices: similarities, differences, and challenges

    PubMed Central

    Gillette, Jane; Cunha-Cruz, Joana; Gilbert, Ann; Speed-McIntyre, Pollene; Zhou, Lingmei; DeRouen, Timothy

    2013-01-01

    Practice-based research should be performed in all practice settings if the results are to be applied to all settings. However, some practice settings, such as community clinics, have unique features that may make the conduct of such research more challenging. The purpose of this article is to describe and compare the similarities and unique challenges related to conducting research in community clinics compared to private practices within the Northwest Practice-Based REsearch Collaborative in Evidence-Based DENTistry (PRECEDENT) network. Information was obtained from meetings with general dentists, a survey of general dentists (N = 253), and a clinical examination and record review of a systemic random sample of patients visiting community clinics and private practices. (N = 1903)—all part of a dental practice-based research network. The processes of conducting research, the dentist and patient sociodemographic characteristics, the prevalence of oral diseases, and the dental treatments received in community clinics and private practices were compared. Both community clinics and private practices have the clinical treatment of the patients as their priority and have time constraints on research. The processes of research training, obtaining informed consent, and collecting, transmitting, and securely maintaining research data are also similar. The patient populations and treatment needs differ substantially between community clinics and private practices, with a higher prevalence of dental caries and higher restorative treatment needs in the community clinic patients. The process of study participant selection and follow-up for research and the dentist and staff work arrangements also vary between the two practice settings. Although community clinic patients and their dental healthcare providers have different research needs and challenges than their counterparts in private practice, practice-based research can be successfully PMID:25429251

  17. Scientific Research Activity of Students Pre-Service Teachers of Sciences at University: The Aspects of Understanding, Situation and Improvement

    ERIC Educational Resources Information Center

    Lamanauskas, Vincentas; Augiene, Dalia

    2017-01-01

    The development of student abilities of scientific research activity (SRA) in the process of studies appears as a highly important area. In the course of studies, students not only increase their general competencies, acquire professional abilities and skills but also learn to conduct research. This does not mean that all students will build their…

  18. 78 FR 32228 - Cotton Research and Promotion Program: Determination of Whether To Conduct a Referendum Regarding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    ... DEPARTMENT OF AGRICULTURE Agricultural Marketing Service [AMS-CN-12-0029] Cotton Research and Promotion Program: Determination of Whether To Conduct a Referendum Regarding 1990 Amendments to the Cotton... of the 1990 amendments to the Cotton Research and Promotion Act (Act). The 1990 amendments require...

  19. The NORDA (Naval Ocean Research and Development Activity) Review.

    DTIC Science & Technology

    1986-03-01

    H 1/3). sea ice edge. sounders with bottom pressure gauges , conductivity- and surface wind speed is now being actively pursued in temperature-depth...actively pursuing these fiscal year. After gauging the status of naval electronic possibilities in the United States, Canada, and Japan for charting...the in situ using specimens collected on Leg 101 of the Ocean Drill - conductivity measurements to identify infrequent, but ing Project. Additional

  20. Research use and support needs, and research activity in social care: a cross-sectional survey in two councils with social services responsibilities in the UK.

    PubMed

    Cooke, Jo; Bacigalupo, Ruth; Halladay, Linsay; Norwood, Hayley

    2008-09-01

    The purpose of this study was to investigate the level of research activity, research use, research interests and research skills in the social care workforce in two UK councils with social service responsibilities (CSSRs). A cross-sectional survey was conducted of the social care workforce in two CSSRs (n = 1512) in 2005. The sample was identified in partnership with the councils, and included employees with professional qualifications (social workers and occupational therapists); staff who have a role to assess, plan and monitor care; service managers; commissioners of services; and those involved with social care policy, information management and training. The survey achieved a response rate of 24% (n = 368). The Internet was reported as an effective source of research information; conversely, research-based guidelines were reported to have a low impact on practice. Significant differences were found in research use, by work location, and postgraduate training. Most respondents saw research as useful for practice (69%), and wanted to collaborate in research (68%), but only 11% were planning to do research within the next 12 months. Having a master's degree was associated with a greater desire to lead or collaborate in research. A range of research training needs, and the preferred modes of delivery were identified. Support to increase research activity includes protected time and mentorship. The study concludes that a range of mechanisms to make research available for the social care workforce needs to be in place to support evidence-informed practice. Continual professional development to a postgraduate level supports the use and production of evidence in the social care workforce, and promotes the development of a research culture. The term research is used to include service user consultations, needs assessment and service evaluation. The findings highlight a relatively large body of the social care workforce willing to collaborate and conduct research

  1. An annotated bibliography of scientific literature on research and management activities conducted in Manitou Experimental Forest

    Treesearch

    Ilana Abrahamson

    2012-01-01

    The Manitou Experimental Forest (MEF) is part of the USDA Forest Service Rocky Mountain Research Station. Established in 1936, its early research focused on range and watershed management. Currently, the site is home to several meteorological, ecological and biological research initiatives. Our collaborators include the University of Colorado, Colorado State University...

  2. 50 CFR 600.745 - Scientific research activity, exempted fishing, and exempted educational activity.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... collection designed to capture and land quantities of fish for product development, market research, and/or... 50 Wildlife and Fisheries 12 2014-10-01 2014-10-01 false Scientific research activity, exempted...-STEVENS ACT PROVISIONS General Provisions for Domestic Fisheries § 600.745 Scientific research activity...

  3. 50 CFR 600.745 - Scientific research activity, exempted fishing, and exempted educational activity.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... collection designed to capture and land quantities of fish for product development, market research, and/or... 50 Wildlife and Fisheries 12 2012-10-01 2012-10-01 false Scientific research activity, exempted...-STEVENS ACT PROVISIONS General Provisions for Domestic Fisheries § 600.745 Scientific research activity...

  4. 50 CFR 600.745 - Scientific research activity, exempted fishing, and exempted educational activity.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... collection designed to capture and land quantities of fish for product development, market research, and/or... 50 Wildlife and Fisheries 12 2013-10-01 2013-10-01 false Scientific research activity, exempted...-STEVENS ACT PROVISIONS General Provisions for Domestic Fisheries § 600.745 Scientific research activity...

  5. 50 CFR 600.745 - Scientific research activity, exempted fishing, and exempted educational activity.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... collection designed to capture and land quantities of fish for product development, market research, and/or... 50 Wildlife and Fisheries 10 2011-10-01 2011-10-01 false Scientific research activity, exempted...-STEVENS ACT PROVISIONS General Provisions for Domestic Fisheries § 600.745 Scientific research activity...

  6. 50 CFR 600.745 - Scientific research activity, exempted fishing, and exempted educational activity.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... collection designed to capture and land quantities of fish for product development, market research, and/or... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Scientific research activity, exempted...-STEVENS ACT PROVISIONS General Provisions for Domestic Fisheries § 600.745 Scientific research activity...

  7. How to conduct research on burnout: advantages and disadvantages of a unidimensional approach in burnout research

    PubMed Central

    Brenninkmeijer, V; VanYperen, N

    2003-01-01

    When conducting research on burnout, it may be difficult to decide whether one should report results separately for each burnout dimension or whether one should combine the dimensions. Although the multidimensionality of the burnout concept is widely acknowledged, for research purposes it is sometimes convenient to regard burnout as a unidimensional construct. This article deals with the question of whether and when it may be appropriate to treat burnout as a unidimensional variable, and presents a decision rule to distinguish between people high and low in burnout. To develop a guideline for obtaining a dichotomous measure of burnout, the scores on the Utrecht Burnout Scale (UBOS) of 44 well functioning individuals were compared with the scores of 29 individuals diagnosed as suffering from burnout. Based on these data, the authors recommend the "exhaustion + 1" criterion for research in non-clinical populations. Following this criterion, individuals can be considered as burnt out when they report, compared to a norm group, high emotional exhaustion, in combination with high depersonalisation or low personal accomplishment. The criterion may be used to estimate the percentage in a sample of individuals in a state of burnout. PMID:12782742

  8. Transparent electrical conducting films by activated reactive evaporation

    DOEpatents

    Bunshah, R.; Nath, P.

    1982-06-22

    Process and apparatus for producing transparent electrical conducting thin films by activated reactive evaporation is disclosed. Thin films of low melting point metals and alloys, such as indium oxide and indium oxide doped with tin, are produced by physical vapor deposition. The metal or alloy is vaporized by electrical resistance heating in a vacuum chamber, oxygen and an inert gas such as argon are introduced into the chamber, and vapor and gas are ionized by a beam of low energy electrons in a reaction zone between the resistance heater and the substrate. There is a reaction between the ionized oxygen and the metal vapor resulting in the metal oxide which deposits on the substrate as a thin film which is ready for use without requiring post deposition heat treatment. 1 fig.

  9. Ensuring PhD development of responsible conduct of research behaviors: who's responsible?

    PubMed

    Titus, Sandra L; Ballou, Janice M

    2014-03-01

    The importance of public confidence in scientific findings and trust in scientists cannot be overstated. Thus, it becomes critical for the scientific community to focus on enhancing the strategies used to educate future scientists on ethical research behaviors. What we are lacking is knowledge on how faculty members shape and develop ethical research standards with their students. We are presenting the results of a survey with 3,500 research faculty members. We believe this is the first report on how faculty work with and educate their PhD students on basic research standards. Specifically, we wanted to determine whether individual faculty members, who are advisors or mentors, differ in how they implemented components of responsible conduct of research (RCR) with their PhD students. Mentors were more likely than advisors or supervisors to report working with all of their PhDs, who graduated in the last 5 years, on the 17 recognized critical components of RCR training and research skill development. We also found about half of the faculty members believe RCR is an institutional responsibility versus a faculty responsibility. Less than a quarter have had opportunities to participate in faculty training to be a better mentor, advisor, or research teacher, and about one third of faculty did not or could not remember whether they had guidelines related to their responsibilities to PhD students. We discuss the implications of our findings and focus on ways that PhD research mentoring can be enhanced.

  10. Positive Activities: Qualitative Research with Parents. Solutions Research. Research Report. DCSF-RR142

    ERIC Educational Resources Information Center

    Department for Children, Schools and Families, 2009

    2009-01-01

    This research was commissioned by COI and DCSF to understand in depth, the barriers, motivators and messages for parents to encourage participation in positive activities for young people. Within this the research was designed to understand the level of influence of parents in whether a young person participates/what a young person might…

  11. Unusually conductive carbon-inherently conducting polymer (ICP) composites: Synthesis and characterization

    NASA Astrophysics Data System (ADS)

    Bourdo, Shawn Edward

    Two groups of materials that have recently come to the forefront of research initiatives are carbon allotropes, especially nanotubes, and conducting polymers-more specifically inherently conducting polymers. The terms conducting polymers and inherently conducting polymers sometimes are used interchangeably without fully acknowledging a major difference in these terms. Conducting polymers (CPs) and inherently conducting polymers (ICPs) are both polymeric materials that conduct electricity, but the difference lies in how each of these materials conducts electricity. For CPs of the past, an electrically conductive filler such as metal particles, carbon black, or graphite would be blended into a polymer (insulator) allowing for the CP to carry an electric current. An ICP conducts electricity due to the intrinsic nature of its chemical structure. The two materials at the center of this research are graphite and polyaniline. For the first time, a composite between carbon allotropes (graphite) and an inherently conducting polymer (PANI) has exhibited an electrical conductivity greater than either of the two components. Both components have a plethora of potential applications and therefore the further investigation could lead to use of these composites in any number of technologies. Touted applications that use either conductive carbons or ICPs exist in a wide range of fields, including electromagnetic interference (EMI) shielding, radar evasion, low power rechargeable batteries, electrostatic dissipation (ESD) for anti-static textiles, electronic devices, light emitting diodes (LEDs), corrosion prevention, gas sensors, super capacitors, photovoltaic cells, and resistive heating. The main motivation for this research has been to investigate the connection between an observed increase in conductivity and structure of composites. Two main findings have resulted from the research as related to the observed increase in conductivity. The first was the structural evidence from

  12. Xanthine derivatives without PDE effect stimulate voltage-activated chloride conductance of toad skin.

    PubMed

    Nagel, Wolfram; Katz, Uri

    2003-02-01

    The effect of xanthine derivatives on the voltage-activated Cl(-) conductance (G(Cl)) of amphibian skin was analyzed. 3-Isobutyl-1-methylxanthine (IBMX) and the recently synthesized xanthine derivatives 3,7-dimethyl-1-propyl xanthine (X-32) and 3,7-dimethyl-1-isobutyl xanthine (X-33), which lack inhibitory effects on phosphodiesterases in CHO and Calu-3 cells, increased voltage-activated G(Cl) without effect on baseline conductance at inactivating voltage. Half-maximal stimulation of G(Cl) occurred at 108 +/- 9 microM for X-32 and X-33 after apical or basolateral application. The stimulation of G(Cl), which occurs only in the presence of Cl(-) in the mucosal solution, is caused by a shift of the voltage sensitivity to lower clamp potentials and an increase of the maximally activated level. Furosemide reversed both the shift of sensitivity and the increase in magnitude. These patterns are fundamentally different from those seen after application of membrane-permeant, nonmetabolized analogs of cAMP, and they indicate that the xanthines stimulate G(Cl) directly. This notion is strengthened by the lack of influence on intracellular cAMP content, which is consistent with the observations in CHO and Calu-3 cells. We propose that the xanthine derivatives increase the voltage sensitivity of a regulative component in the conductive Cl(-) pathway across amphibian skin.

  13. Use of modular amphibious vehicles for conducting research in coastal zone

    NASA Astrophysics Data System (ADS)

    Zeziulin, Denis; Makarov, Vladimir; Belyaev, Alexander; Beresnev, Pavel; Kurkin, Andrey

    2016-04-01

    The project aims to create workable running systems of research complexes, moving along the bottom of coastal areas (in shallow waters) for investigation of waves, currents, sediment transport; investigation of ecosystems and biodiversity assessment of organisms; inspection and monitoring environmental conditions and anthropogenic load on nature; bathymetric studies. With all the variety of functional capabilities of modern robotic systems, possibilities of their application in the context of the study of coastal zones are extremely limited. Conducting research using aerial vehicles is limited to safety conditions of flight. Use of floating robotic systems in environmental monitoring and ecosystem research is only possible in conditions of relatively «soft» wave climate of the coastal zone. For these purposes, there are special amphibians such as remote-controlled vehicle Surf Rover [Daily, William R., Mark A. Johnson, and Daniel A. Oslecki. «Initial Development of an Amphibious ROV for Use in Big Surf.» Marine Technology Society 28.1 (1994): 3-10. Print.], mobile system MARC-1 [«The SPROV'er.» Florida Institute of Technology: Department of Marine and. Environmental Systems. Web. 05 May 2010.]. The paper describes methodological approaches to the selection of the design parameters of a new system.

  14. Making Strategic Decisions: Conducting and Using Research on the Impact of Sequenced Library Instruction

    ERIC Educational Resources Information Center

    Lundstrom, Kacy; Martin, Pamela; Cochran, Dory

    2016-01-01

    This study explores the relationship between course grades and sequenced library instruction interventions throughout psychology students' curriculum. Researchers conducted this study to inform decisions about sustaining and improving program integrations for first- and second-year composition courses and to improve discipline-level integrations.…

  15. Writing Interview Protocols and Conducting Interviews: Tips for Students New to the Field of Qualitative Research

    ERIC Educational Resources Information Center

    Jacob, Stacy A.; Furgerson, S. Paige

    2012-01-01

    Students new to doing qualitative research in the ethnographic and oral traditions, often have difficulty creating successful interview protocols. This article offers practical suggestions for students new to qualitative research for both writing interview protocol that elicit useful data and for conducting the interview. This piece was originally…

  16. Superoxide activates a GDP-sensitive proton conductance in skeletal muscle mitochondria from king penguin (Aptenodytes patagonicus).

    PubMed

    Talbot, Darren A; Hanuise, Nicolas; Rey, Benjamin; Rouanet, Jean-Louis; Duchamp, Claude; Brand, Martin D

    2003-12-26

    We present the partial nucleotide sequence of the avian uncoupling protein (avUCP) gene from king penguin (Aptenodytes patagonicus), showing that the protein is 88-92% identical to chicken (Gallus gallus), turkey (Meleagris gallopavo), and hummingbird (Eupetomena macroura). We show that superoxide activates the proton conductance of mitochondria isolated from king penguin skeletal muscle. GDP abolishes the superoxide-activated proton conductance, indicating that it is mediated via avUCP. In the absence of superoxide there is no GDP-sensitive component of the proton conductance from penguin muscle mitochondria demonstrating that avUCP plays no role in the basal proton leak.

  17. Update on U.S.EPA Cookstove Research Activities

    EPA Science Inventory

    The presentation includes background information on EPA's stove research, focuses on cookstove testing for air pollutant emissions and energy efficiency, and briefly describes current research activities. Ongoing activities are highlighted, and EPA contacts are provided.

  18. Seven Activities for Enhancing the Replicability of Evidence-Based Practices. Research-to-Results Brief. Publication #2007-30

    ERIC Educational Resources Information Center

    Metz, Allison J. R.; Bowie, Lillian; Blase, Karen

    2007-01-01

    This brief will define program replication, describe the critical role of "core components" in program replication, and outline seven activities that program developers and researchers can conduct to enhance the replicability of effective program models and facilitate their adoption by other organizations and programs. Outlined is seven specific…

  19. Building Research Capacity of Medical Students and Health Professionals in Rural Communities: Leveraging a Rural Clinical School's Resources to Conduct Research Skills Workshops

    ERIC Educational Resources Information Center

    Lasserre, Kaye E.; Moffatt, Jennifer J.

    2013-01-01

    The paper reports on a project where the objective was for the Rural Clinical School, The University of Queensland, Australia, to design an acceptable model of research skills workshops for medical students and rural health professionals. Eight, interactive research skills workshops focused on skill development were conducted in rural Queensland,…

  20. 12 CFR 550.580 - When may I conduct fiduciary activities without obtaining OTS approval?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false When may I conduct fiduciary activities without obtaining OTS approval? 550.580 Section 550.580 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY FIDUCIARY POWERS OF SAVINGS ASSOCIATIONS Activities Exempt From This Part § 550.580...

  1. 30 CFR 550.208 - If I conduct ancillary activities, what notices must I provide?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 2 2014-07-01 2014-07-01 false If I conduct ancillary activities, what notices must I provide? 550.208 Section 550.208 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT... activity and any mitigation to eliminate or minimize these effects on the marine, coastal, and human...

  2. 30 CFR 550.208 - If I conduct ancillary activities, what notices must I provide?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 2 2012-07-01 2012-07-01 false If I conduct ancillary activities, what notices must I provide? 550.208 Section 550.208 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT... activity and any mitigation to eliminate or minimize these effects on the marine, coastal, and human...

  3. 30 CFR 250.208 - If I conduct ancillary activities, what notices must I provide?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false If I conduct ancillary activities, what notices must I provide? 250.208 Section 250.208 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION... the proposed activity and any mitigation to eliminate or minimize these effects on the marine, coastal...

  4. 30 CFR 550.208 - If I conduct ancillary activities, what notices must I provide?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 2 2013-07-01 2013-07-01 false If I conduct ancillary activities, what notices must I provide? 550.208 Section 550.208 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT... activity and any mitigation to eliminate or minimize these effects on the marine, coastal, and human...

  5. Summary of Research Activities Academic Departments 1981-1982.

    DTIC Science & Technology

    1982-10-01

    M12 MICROCOPY RESOLUTIONI TEST CHART NATION4AL BUREAU OF STAN4DARDS- 1963-A SUMMARY OF RESEARCH ACTIVITIES ACADEMIC I DEPARTMENTS 1 1981-1982 42 4...r I OFFICE OF THE ACADEMIC DEAN I UNITED STATES NAVAL ACADEMY ANNAPOLIS, MARYLAND li. 6 4 | I I SUMMARY OF IRESEARCH ACTIVITIES [ 1981 - 1982 i... activities that contribute to the professional growth of the faculty and outstanding midshipmen may flourish. * The research activities of the faculty

  6. Overview of EPA Superfund human health research program.

    PubMed

    Kowalski, Lorelei; Denne, Jane; Dyer, Robert; Garrahan, Kevin; Wentsel, Randall S

    2002-03-01

    This paper presents major research needs for the Superfund program, and provides an overview of the EPA Office of Research and Development's (ORDs) current human health research program designed to fill some of those data gaps. Research is presented in terms of the risk paradigm and covers exposure, effects, and assessment activities directly funded by Superfund, as well as research not funded by Superfund but directly applicable to Superfund research needs. Research on risk management is not covered. Current research activities conducted by the Superfund program office are also included to provide a full picture of Superfund human health research activities being conducted by EPA.

  7. Teaching Research Methodology through Active Learning

    ERIC Educational Resources Information Center

    Lundahl, Brad W.

    2008-01-01

    To complement traditional learning activities in a masters-level research methodology course, social work students worked on a formal research project which involved: designing the study, constructing measures, selecting a sampling strategy, collecting data, reducing and analyzing data, and finally interpreting and communicating the results. The…

  8. 50 CFR 600.512 - Scientific research.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 50 Wildlife and Fisheries 12 2013-10-01 2013-10-01 false Scientific research. 600.512 Section 600... research. (a) Scientific research activity. Persons planning to conduct scientific research activities on board a scientific research vessel in the EEZ that may be confused with fishing are encouraged to submit...

  9. 50 CFR 600.512 - Scientific research.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 12 2012-10-01 2012-10-01 false Scientific research. 600.512 Section 600... research. (a) Scientific research activity. Persons planning to conduct scientific research activities on board a scientific research vessel in the EEZ that may be confused with fishing are encouraged to submit...

  10. 50 CFR 600.512 - Scientific research.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Scientific research. 600.512 Section 600... research. (a) Scientific research activity. Persons planning to conduct scientific research activities on board a scientific research vessel in the EEZ that may be confused with fishing are encouraged to submit...

  11. 50 CFR 600.512 - Scientific research.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 10 2011-10-01 2011-10-01 false Scientific research. 600.512 Section 600... research. (a) Scientific research activity. Persons planning to conduct scientific research activities on board a scientific research vessel in the EEZ that may be confused with fishing are encouraged to submit...

  12. 50 CFR 600.512 - Scientific research.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 12 2014-10-01 2014-10-01 false Scientific research. 600.512 Section 600... research. (a) Scientific research activity. Persons planning to conduct scientific research activities on board a scientific research vessel in the EEZ that may be confused with fishing are encouraged to submit...

  13. Interplay of activation kinetics and the derivative conductance determines resonance properties of neurons

    NASA Astrophysics Data System (ADS)

    Pena, Rodrigo F. O.; Ceballos, Cesar C.; Lima, Vinicius; Roque, Antonio C.

    2018-04-01

    In a neuron with hyperpolarization activated current (Ih), the correct input frequency leads to an enhancement of the output response. This behavior is known as resonance and is well described by the neuronal impedance. In a simple neuron model we derive equations for the neuron's resonance and we link its frequency and existence with the biophysical properties of Ih. For a small voltage change, the component of the ratio of current change to voltage change (d I /d V ) due to the voltage-dependent conductance change (d g /d V ) is known as derivative conductance (GhDer). We show that both GhDer and the current activation kinetics (characterized by the activation time constant τh) are mainly responsible for controlling the frequency and existence of resonance. The increment of both factors (GhDer and τh) greatly contributes to the appearance of resonance. We also demonstrate that resonance is voltage dependent due to the voltage dependence of GhDer. Our results have important implications and can be used to predict and explain resonance properties of neurons with the Ih current.

  14. 34 CFR 97.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Subjects (Basic ED Policy for Protection of Human Research Subjects) § 97.103 Assuring compliance with this..., appropriate for the research in question, on file with the Office for Human Research Protections, HHS, or any... Human Research Protections, (HHS), or any successor office. (b) Departments and agencies will conduct or...

  15. 45 CFR 46.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Protection of Human Research Subjects § 46.103 Assuring compliance with this policy—research conducted or... file with the Office for Human Research Protections, HHS, or any successor office, and approved for... department and agency heads shall also be made to the Office for Human Research Protections, HHS, or any...

  16. Reflections on moral care when conducting qualitative research about suicide in the United States military.

    PubMed

    Polanco, Marcela; Mancías, Saraí; LeFeber, Tirzah

    2017-09-01

    Critical suicidology (White, Marsh, Kral, & Morris, 2016 ) offers a critique of positivism as the mainstream rhetoric of scientific research. In this article, the authors add a critique to the moral detachment of scientific inquiry (Wilkinson & Kleinman, 2016 ) in suicidology. They provide a discussion at the intersection of theory and research when considering moral care of all stakeholders in the implementation of suicide research toward the development of more humanitarian policies and program alternatives. The authors reflect upon their experience of conducting an Interpretative Phenomenological Analysis (Finlay, 2011 ) on suicide in the U.S. military.

  17. A high-conduction Ge substituted Li3AsS4 solid electrolyte with exceptional low activation energy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sahu, Gayatri; Rangasamy, Ezhiylmurugan; Li, Juchuan

    2014-04-16

    In lithium-ion conducting solid electrolytes the potential to enable high-energy-density secondary batteries and offer distinctive safety features as an advantage over traditional liquid electrolytes is shown. Achieving the combination of high ionic conductivity, low activation energy, and outstanding electrochemical stability in crystalline solid electrolytes is a challenge for the synthesis of novel solid electrolytes. We report an exceptionally low activation energy (Ea) and high room temperature superionic conductivity via facile aliovalent substitution of Li 3AsS 4 by Ge, which increased the conductivity by two orders of magnitude as compared to the parent compound. The composition Li 3.334Ge 0.334As 0.666S 4more » has a high ionic conductivity of 1.12 mScm -1 at 27°C. Local Li + hopping in this material is accompanied by distinctive low activation energy Ea of 0.17 eV being the lowest of Li + solid conductors. Finally, our study demonstrates the efficacy of surface passivation of solid electrolyte to achieve compatibility with metallic lithium electrodes.« less

  18. Highly conductive and porous activated reduced graphene oxide films for high-power supercapacitors.

    PubMed

    Zhang, Li Li; Zhao, Xin; Stoller, Meryl D; Zhu, Yanwu; Ji, Hengxing; Murali, Shanthi; Wu, Yaping; Perales, Stephen; Clevenger, Brandon; Ruoff, Rodney S

    2012-04-11

    We present a novel method to prepare highly conductive, free-standing, and flexible porous carbon thin films by chemical activation of reduced graphene oxide paper. These flexible carbon thin films possess a very high specific surface area of 2400 m(2) g(-1) with a high in-plane electrical conductivity of 5880 S m(-1). This is the highest specific surface area for a free-standing carbon film reported to date. A two-electrode supercapacitor using these carbon films as electrodes demonstrated an excellent high-frequency response, an extremely low equivalent series resistance on the order of 0.1 ohm, and a high-power delivery of about 500 kW kg(-1). While higher frequency and power values for graphene materials have been reported, these are the highest values achieved while simultaneously maintaining excellent specific capacitances and energy densities of 120 F g(-1) and 26 W h kg(-1), respectively. In addition, these free-standing thin films provide a route to simplify the electrode-manufacturing process by eliminating conducting additives and binders. The synthetic process is also compatible with existing industrial level KOH activation processes and roll-to-roll thin-film fabrication technologies. © 2012 American Chemical Society

  19. Integrating high electrical conductivity and photocatalytic activity in cotton fabric by cationizing for enriched coating of negatively charged graphene oxide.

    PubMed

    Sahito, Iftikhar Ali; Sun, Kyung Chul; Arbab, Alvira Ayoub; Qadir, Muhammad Bilal; Jeong, Sung Hoon

    2015-10-05

    Electroconductive textiles have attended tremendous focus recently and researchers are making efforts to increase conductivity of e-textiles, in order to increase the use of such flexible and low cost textile materials. In this study, surface conductivity and photo catalytic activity of standard cotton fabric (SCF) was enhanced by modifying its surface charge, from negative to positive, using Bovine Serum Albumin (BSA) as a cationic agent, to convert it into cationised cotton fabric (CCF). Then, both types of fabrics were dip coated with a simple dip and dry technique for the adsorption of negatively charged graphene oxide (GO) sheets onto its surface. This resulted in 67.74% higher loading amount of GO on the CCF making self-assembly. Finally, this coating was chemically converted by vapor reduction using hydrazine hydrate to reduced graphene oxide (rGO) for restoration of a high electrical conductivity at the fabric surface. Our results revealed that with such high loading of GO, the surface resistance of CCF was only 40Ω/sq as compared to 510Ω/sq of the SCF and a 66% higher photo catalytic activity was also achieved through cationization for improved GO coating. Graphene coated SCF and CCF were characterized using FE-SEM, FTIR, Raman, UV-vis, WAXD, EDX and XPS spectroscopy to ascertain successful reduction of GO to rGO. The effect of BSA treatment on adsorption of cotton fabric was studied using drop shape analyzer to measure contact angle and for thermal and mechanical resistance, the fabric was tested for TGA and tensile strength, respectively. rGO coated fabric also showed slightly improved thermal stability yet a minor loss of strength was observed. The high flexibility, photocatalytic activity and excellent conductivity of this fabric suggests that it can be used as an electrode material for various applications. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. 40 CFR 745.230 - Work practice standards for conducting lead-based paint activities: public and commercial...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.230 Work practice standards for conducting lead-based paint activities: public... lead-based paint activities: public and commercial buildings, bridges and superstructures. [Reserved...

  1. 40 CFR 745.230 - Work practice standards for conducting lead-based paint activities: public and commercial...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.230 Work practice standards for conducting lead-based paint activities: public... lead-based paint activities: public and commercial buildings, bridges and superstructures. [Reserved...

  2. 40 CFR 745.230 - Work practice standards for conducting lead-based paint activities: public and commercial...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.230 Work practice standards for conducting lead-based paint activities: public... lead-based paint activities: public and commercial buildings, bridges and superstructures. [Reserved...

  3. Conducting research with communities of color

    Treesearch

    Leo McAvoy; Patricia L. Winter; Corliss W. Outley; Dan McDonald; Deborah J. Chavez

    2000-01-01

    This article presents the major challenges facing those who want to address the issues of race and ethnicity through research with communities of color; general methodological recommendations appropriate to many communities of color; and, specific research method recommendations for African American, American Indian, and Hispanic American communities.

  4. Reflecting on the Challenges of Conducting Research across National and Linguistic Borders: Lessons from the Field

    ERIC Educational Resources Information Center

    Rubinstein-Ávila, Eliane

    2009-01-01

    Whether a study is qualitative or quantitative, the process of data collection is not as orderly as it may seem when described in published research reports, articles, or books. Data collection may be more challenging when conducting research across national and linguistic borders. In this article, I share and reflect upon the complex and messy…

  5. New Developments in NASA's Rodent Research Hardware for Conducting Long Duration Biomedical and Basic Research in Space

    NASA Technical Reports Server (NTRS)

    Shirazi, Yasaman; Choi, S.; Harris, C.; Gong, C.; Fisher, R. J.; Beegle, J. E.; Stube, K. C.; Martin, K. J.; Nevitt, R. G.; Globus, R. K.

    2017-01-01

    common human diseases. Together, the hardware improvements (enrichment, telemetry sensors, cameras), new capabilities (live animal return), and experience that the Rodent Research team has gained working with principal investigator teams and ISS crew to conduct complex experiments on orbit are expanding capabilities for long duration rodent research on the ISS to achieve both basic science and biomedical research objectives.

  6. A Decision Process for Determining Whether to Conduct Responder Health Research Following Disasters

    PubMed Central

    Decker, John A.; Kiefer, Max; Reissman, Dori B.; Funk, Renée; Halpin, John; Bernard, Bruce; Ehrenberg, Richard L.; Schuler, Christine R.; Whelan, Elizabeth; Myers, Kyle; Howard, John

    2015-01-01

    Background Disasters often set the stage for scientific inquiry within the field of occupational safety and health. This is especially true when the long-term consequences of exposures associated with a particular disaster are unclear. However, a responder research study can be costly and difficult to design, and researchers must consider whether the proposed study will produce useful, reliable results and is a prudent public health investment. Methods Senior NIOSH scientists, experienced with disaster response and representing the disciplines of epidemiology, occupational medicine and psychiatry, and industrial hygiene, were convened at the request of the NIOSH Director to develop a decision process to help determine when to conduct responder health research following disasters. Results The decision process can be broken down into various components, including scientific rationale that should be formally recognized as critical to efficiently and effectively determine whether a research study is warranted. The scientific rationale includes certain controlling or “gatekeeper” factors that should be present to proceed with research. Providing the foundation for responder disaster research also requires strategizing before an event occurs, so that critical baseline and comparison data can be collected. Conclusions The recommended framework should ensure that research that is most needed and justified will be identified and prioritized. PMID:23716371

  7. Steps toward validity in active living research: research design that limits accusations of physical determinism.

    PubMed

    Riggs, William

    2014-03-01

    "Active living research" has been accused of being overly "physically deterministic" and this article argues that urban planners must continue to evolve research and address biases in this area. The article first provides background on how researchers have dealt with the relationship between the built environment and health over years. This leads to a presentation of how active living research might be described as overly deterministic. The article then offers lessons for researchers planning to embark in active-living studies as to how they might increase validity and minimize criticism of physical determinism. © 2013 Published by Elsevier Ltd.

  8. An Action Research Inquiry into the Relationship Among Aerobic Activities, Memory, and Stress with Students Identified as Gifted

    NASA Astrophysics Data System (ADS)

    Ford, Denise Marie

    Students identified as gifted come from varying socio-economic strata and nationalities with a range of talents and temperaments comprising a diverse community. They may experience stress for a variety of reasons. Although a certain amount of stress can enhance the learning process, too much stress can impede learning, especially memory. Strategies have been offered for relieving stress, yet the benefits of physical activities as stress reducers for the gifted have frequently been overlooked. The purpose of this study was to investigate the relationship among aerobic activity, stress, and memory ability in students in an elementary school gifted program. An exceptional aspect of this research was that the students were an integral part of their own study. As co-researchers they had a vested interest in what they were doing, enhancing the significance of the experience and heightening learning. This action research project conducted in a mid-western school district with fourth and fifth grade students examined the impact of aerobic movement on physical indicators of stress and memory. The study lasted twelve weeks with data collected on physical indicators of stress, memory test scores, parent observations, interviews with students, a parent focus group session, observational data, student comments, and investigator/teacher journal. By infusing regular exercise into curricula, stress levels in students identified as gifted were examined. Students' scores on declarative memory tasks conducted with and without an accompanying aerobic activity were documented. Students learned of the delicate relationship between stress and memory as they studied the physiology of the brain. Twenty-four hour retention rates of declarative memory items were higher when a 20-minute aerobic activity intervention preceded the memory activity. Perceived stress levels were lowered for 14 of the 16 co-researchers. Students indicated a positive attitude toward physical activity and its

  9. Maternal smoking during pregnancy and offspring conduct problems: evidence from 3 independent genetically sensitive research designs.

    PubMed

    Gaysina, Darya; Fergusson, David M; Leve, Leslie D; Horwood, John; Reiss, David; Shaw, Daniel S; Elam, Kit K; Natsuaki, Misaki N; Neiderhiser, Jenae M; Harold, Gordon T

    2013-09-01

    Several studies report an association between maternal smoking during pregnancy and offspring conduct disorder. However, past research evidences difficulty in disaggregating prenatal environmental influences from genetic and postnatal environmental influences. To examine the relationship between maternal smoking during pregnancy and offspring conduct problems among children reared by genetically related mothers and genetically unrelated mothers. The following 3 studies using distinct but complementary research designs were used: The Christchurch Health and Development Study (a longitudinal cohort study that includes biological and adopted children), the Early Growth and Development Study (a longitudinal adoption-at-birth study), and the Cardiff IVF (In Vitro Fertilization) Study (an adoption-at-conception study among genetically related families and genetically unrelated families). Maternal smoking during pregnancy was measured as the mean number of cigarettes per day (0, 1-9, or 10) smoked during pregnancy. Possible covariates were controlled for in the analyses, including child sex, birth weight, race/ethnicity, placement age, and breastfeeding, as well as maternal education and maternal age at birth and family breakdown, parenting practices, and family socioeconomic status. Offspring conduct problems (age range, 4-10 years) reported by parents or teachers using the behavior rating scales by Rutter and Conners, the Child Behavior Checklist and the Children's Behavior Questionnaire Short Form, and the Strengths and Difficulties Questionnaire. A significant association between maternal smoking during pregnancy and offspring conduct problems was observed among children reared by genetically related mothers and genetically unrelated mothers. Results from a meta-analysis affirmed this pattern of findings across pooled study samples. Findings across 3 studies using a complement of genetically sensitive research designs suggest that smoking during pregnancy is a

  10. Maternal smoking during pregnancy and offspring conduct problems: Evidence from three independent genetically-sensitive research designs

    PubMed Central

    Gaysina, Darya; Fergusson, David M.; Leve, Leslie D.; Horwood, John; Reiss, David; Shaw, Daniel S.; Elam, Kit K.; Natsuaki, Misaki N.; Neiderhiser, Jenae M.; Harold, Gordon T.

    2013-01-01

    Context A number of studies report an association between maternal smoking during pregnancy and offspring conduct disorder. However, past research evidences difficulty disaggregating prenatal environmental from genetic and postnatal environmental influences. Objective To examine the relationship between maternal smoking during pregnancy and offspring conduct problems among children reared by genetically-related and genetically-unrelated mothers. Design, Setting and Participants Three studies employing distinct but complementary research designs were utilized: The Christchurch Health and Development Study (a longitudinal cohort study that includes biological and adopted children), the Early Growth and Development Study (a longitudinal adoption at birth study), and the Cardiff IVF Study (genetically-related and -unrelated families; an adoption at conception study). Maternal smoking during pregnancy was measured as the average number of cigarettes/day (0, 1–9 or 10+) smoked during pregnancy. A number of possible covariates (child gender, ethnicity, birth weight, breast feeding, maternal age at birth, maternal education, family SES, family breakdown, placement age, and parenting practices) were controlled in the analyses. Main Outcome Measure Child conduct problems (age 4–10 years) reported by parents and/or teachers using the Rutter and Conners behaviour scales, the Child Behavior Checklist and Children's Behavior Questionnaire, and the Strengths and Difficulties Questionnaire. Results A significant association between maternal smoking during pregnancy and child conduct problems was observed among children reared by genetically-related and genetically-unrelated mothers. Results from a meta-analysis affirmed this pattern of findings across pooled study samples. Conclusions Findings across the three studies using a complement of genetically-sensitive research designs suggest smoking during pregnancy is a prenatal risk factor for offspring conduct problems, when

  11. Conducting Classroom Design Research with Teachers

    ERIC Educational Resources Information Center

    Stephan, Michelle. L.

    2015-01-01

    Design research is usually motivated by university members with experience and interest in building theory and instructional designs in collaboration with one teacher. Typically, the teacher is considered as a member of the research team, with the primary responsibility of implementing instruction. However, in this chapter, I describe a Classroom…

  12. 75 FR 69295 - Taking and Importing Marine Mammals; Navy Training Activities Conducted Within the Northwest...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... partners, the comparative study will be designed and conducted for specific sites during intervals of both...' analysis of these measures is included in the Response to Public Comment section. Research The Navy provides a significant amount of funding and support to marine research. In the past five years [[Page...

  13. Integrating Responsible Conduct of Research Education into Undergraduate Biochemistry and Molecular Biology Laboratory Curricula

    ERIC Educational Resources Information Center

    Hendrickson, Tamara L.

    2015-01-01

    Recently, a requirement for directed responsible conduct in research (RCR) education has become a priority in the United States and elsewhere. In the US, both the National Institutes of Health and the National Science Foundation require RCR education for all students who are financially supported by federal awards. The guidelines produced by these…

  14. Performance-Enhanced Activated Carbon Electrodes for Supercapacitors Combining Both Graphene-Modified Current Collectors and Graphene Conductive Additive

    PubMed Central

    Wang, Rubing; Qian, Yuting; Li, Weiwei; Zhu, Shoupu; Liu, Fengkui; Guo, Yufen; Chen, Mingliang; Li, Qi; Liu, Liwei

    2018-01-01

    Graphene has been widely used in the active material, conductive agent, binder or current collector for supercapacitors, due to its large specific surface area, high conductivity, and electron mobility. However, works simultaneously employing graphene as conductive agent and current collector were rarely reported. Here, we report improved activated carbon (AC) electrodes (AC@G@NiF/G) simultaneously combining chemical vapor deposition (CVD) graphene-modified nickel foams (NiF/Gs) current collectors and high quality few-layer graphene conductive additive instead of carbon black (CB). The synergistic effect of NiF/Gs and graphene additive makes the performances of AC@G@NiF/G electrodes superior to those of electrodes with CB or with nickel foam current collectors. The performances of AC@G@NiF/G electrodes show that for the few-layer graphene addition exists an optimum value around 5 wt %, rather than a larger addition of graphene, works out better. A symmetric supercapacitor assembled by AC@G@NiF/G electrodes exhibits excellent cycling stability. We attribute improved performances to graphene-enhanced conductivity of electrode materials and NiF/Gs with 3D graphene conductive network and lower oxidation, largely improving the electrical contact between active materials and current collectors. PMID:29762528

  15. Performance-Enhanced Activated Carbon Electrodes for Supercapacitors Combining Both Graphene-Modified Current Collectors and Graphene Conductive Additive.

    PubMed

    Wang, Rubing; Qian, Yuting; Li, Weiwei; Zhu, Shoupu; Liu, Fengkui; Guo, Yufen; Chen, Mingliang; Li, Qi; Liu, Liwei

    2018-05-15

    Graphene has been widely used in the active material, conductive agent, binder or current collector for supercapacitors, due to its large specific surface area, high conductivity, and electron mobility. However, works simultaneously employing graphene as conductive agent and current collector were rarely reported. Here, we report improved activated carbon (AC) electrodes (AC@G@NiF/G) simultaneously combining chemical vapor deposition (CVD) graphene-modified nickel foams (NiF/Gs) current collectors and high quality few-layer graphene conductive additive instead of carbon black (CB). The synergistic effect of NiF/Gs and graphene additive makes the performances of AC@G@NiF/G electrodes superior to those of electrodes with CB or with nickel foam current collectors. The performances of AC@G@NiF/G electrodes show that for the few-layer graphene addition exists an optimum value around 5 wt %, rather than a larger addition of graphene, works out better. A symmetric supercapacitor assembled by AC@G@NiF/G electrodes exhibits excellent cycling stability. We attribute improved performances to graphene-enhanced conductivity of electrode materials and NiF/Gs with 3D graphene conductive network and lower oxidation, largely improving the electrical contact between active materials and current collectors.

  16. Departmental Contexts and Faculty Research Activity in Norway

    ERIC Educational Resources Information Center

    Smeby, Jens-Christian; Try, Sverre

    2005-01-01

    The aim of the paper is to examine the relationship between departmental attributes and university faculty research activity. Since individual and departmental factors are highly interrelated, individual attributes are included in a hierarchical linear model taking into consideration the nested structure of the data. Research activity is measured…

  17. Conducting Original, Hands-On Astronomical Research in the Classroom

    NASA Astrophysics Data System (ADS)

    Corneau, M. J.

    2009-12-01

    teachers to convey moderately complex computer science, optical, geographic, mathematical, informational and physical principles through hands-on telescope operations. In addition to the general studies aspects of classroom internet-based astronomy, Tzec Maun supports real science by enabling operators precisely point telescopes and acquire extremely faint, magnitude 19+ CCD images. Thanks to the creative Team of Photometrica (photometrica.org), my teams now have the ability to process and analyze images online and produce results in short order. Normally, astronomical data analysis packages cost greater than thousands of dollars for single license operations. Free to my team members, Photometrica allows students to upload their data to a cloud computing server and read precise photometric and/or astrometric results. I’m indebted to Michael and Geir for their support. The efficacy of student-based research is well documented. The Council on Undergraduate Research defines student research as, "an inquiry or investigation conducted by an undergraduate that makes an original intellectual or creative contribution to the discipline." (http://serc.carleton.edu/introgeo/studentresearch/What. Teaching from Tzec Maun in the classroom is the most original teaching research I can imagine. I very much look forward to presenting this program to the convened body.

  18. Immersion research education: students as catalysts in international collaboration research.

    PubMed

    Anderson, K H; Friedemann, M L; Bűscher, A; Sansoni, J; Hodnicki, D

    2012-12-01

    This paper describes an international nursing and health research immersion program. Minority students from the USA work with an international faculty mentor in teams conducting collaborative research. The Minority Health International Research Training (MHIRT) program students become catalysts in the conduct of cross-cultural research. To narrow the healthcare gap for disadvantaged families in the USA and partner countries. Faculty from the USA, Germany, Italy, Colombia, England, Austria and Thailand formed an international research and education team to explore and compare family health issues, disparities in chronic illness care, social inequities and healthcare solutions. USA students in the MHIRT program complete two introductory courses followed by a 3-month research practicum in a partner country guided by faculty mentors abroad. The overall program development, student study abroad preparation, research project activities, cultural learning, and student and faculty team outcomes are explored. Cross-fertilization of research, cultural awareness and ideas about improving family health occur through education, international exchange and research immersion. Faculty research and international team collaboration provide opportunities for learning about research, health disparities, cultural influences and healthcare systems. The students are catalysts in the research effort, the dissemination of research findings and other educational endeavours. Five steps of the collaborative activities lead to programmatic success. MHIRT scholars bring creativity, enthusiasm, and gain a genuine desire to conduct health research about families with chronic illness. Their cultural learning stimulates career plans that include international research and attention to vulnerable populations. © 2012 The Authors. International Nursing Review © 2012 International Council of Nurses.

  19. Immersion Research Education: Students as Catalysts in International Collaboration Research

    PubMed Central

    Anderson, Kathryn Hoehn; Friedemann, Marie-Luise; Bűscher, Andreas; Sansoni, Julita; Hodnicki, Donna

    2012-01-01

    Background This paper describes an international nursing and health research immersion program. Minority students from the United States of America (USA) work with an international faculty mentor in teams conducting collaborative research. The Minority Health International Research Training (MHIRT) program students become catalysts in the conduct of cross-cultural research. Aim To narrow the health care gap for disadvantaged families in the U.S.A. and partner countries. Methods Faculty from the U.S.A, Germany, Italy, Colombia, England, Austria, and Thailand formed an international research and education team to explore and compare family health issues, disparities in chronic illness care, social inequities, and health care solutions. U.S.A. students in the MHIRT program complete two introductory courses followed by a three-month research practicum in a partner country guided by faculty mentors abroad. The overall program development, student study abroad preparation, research project activities, cultural learning, and student and faculty team outcomes are explored. Results Cross-fertilization of research, cultural awareness, and ideas about improving family health occur through education, international exchange, and research immersion. Faculty research and international team collaboration provide opportunities for learning about research, health disparities, cultural influences, and health care systems. The students are catalysts in the research effort, the dissemination of research findings, and other educational endeavours. Five steps of the collaborative activities lead to programmatic success. Conclusions MHIRT scholars bring creativity, enthusiasm, and gain a genuine desire to conduct health research about families with chronic illness. Their cultural learning stimulates career plans that include international research and attention to vulnerable populations. PMID:23134134

  20. Activation Theory and Uses and Gratifications Research.

    ERIC Educational Resources Information Center

    Tate, E. D.

    Uses and gratifications research involves a critical appraisal of conceptual and theoretical issues in mass communication and is concerned with what audience members do with the media. Activation theory understands people as active manipulators of their environment. (Activation refers to that level of psychological and physiological excitement an…

  1. 38 CFR 16.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... disposition of applications and proposals for research to be conducted or supported by a Federal Department or... PROTECTION OF HUMAN SUBJECTS § 16.120 Evaluation and disposition of applications and proposals for research... will evaluate all applications and proposals involving human subjects submitted to the department or...

  2. 32 CFR 219.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... HUMAN SUBJECTS § 219.103 Assuring compliance with this policy—research conducted or supported by any... Office for Human Research Protections, HHS, or any successor office, and approved for federalwide use by... and agency heads shall also be made to the Office for Human Research Protections, HHS, or any...

  3. 39 CFR 255.3 - Nondiscrimination under any program or activity conducted by the Postal Service.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Nondiscrimination under any program or activity conducted by the Postal Service. 255.3 Section 255.3 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION ACCESS OF PERSONS WITH DISABILITIES TO POSTAL SERVICE PROGRAMS, ACTIVITIES...

  4. 32 CFR 56.10 - Ensuring compliance with this part in programs and activities conducted by the Department of...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 1 2012-07-01 2012-07-01 false Ensuring compliance with this part in programs and activities conducted by the Department of Defense. 56.10 Section 56.10 National Defense Department... THE BASIS OF HANDICAP IN PROGRAMS AND ACTIVITIES ASSISTED OR CONDUCTED BY THE DEPARTMENT OF DEFENSE...

  5. 32 CFR 56.10 - Ensuring compliance with this part in programs and activities conducted by the Department of...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 1 2014-07-01 2014-07-01 false Ensuring compliance with this part in programs and activities conducted by the Department of Defense. 56.10 Section 56.10 National Defense Department... THE BASIS OF HANDICAP IN PROGRAMS AND ACTIVITIES ASSISTED OR CONDUCTED BY THE DEPARTMENT OF DEFENSE...

  6. 32 CFR 56.10 - Ensuring compliance with this part in programs and activities conducted by the Department of...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Ensuring compliance with this part in programs and activities conducted by the Department of Defense. 56.10 Section 56.10 National Defense Department... THE BASIS OF HANDICAP IN PROGRAMS AND ACTIVITIES ASSISTED OR CONDUCTED BY THE DEPARTMENT OF DEFENSE...

  7. 32 CFR 56.10 - Ensuring compliance with this part in programs and activities conducted by the Department of...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 1 2013-07-01 2013-07-01 false Ensuring compliance with this part in programs and activities conducted by the Department of Defense. 56.10 Section 56.10 National Defense Department... THE BASIS OF HANDICAP IN PROGRAMS AND ACTIVITIES ASSISTED OR CONDUCTED BY THE DEPARTMENT OF DEFENSE...

  8. 32 CFR 56.10 - Ensuring compliance with this part in programs and activities conducted by the Department of...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 1 2011-07-01 2011-07-01 false Ensuring compliance with this part in programs and activities conducted by the Department of Defense. 56.10 Section 56.10 National Defense Department... THE BASIS OF HANDICAP IN PROGRAMS AND ACTIVITIES ASSISTED OR CONDUCTED BY THE DEPARTMENT OF DEFENSE...

  9. 12 CFR 211.29 - Applications by state branches and state agencies to conduct activities not permissible for...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Comptroller imposes a quantitative limitation on the conduct of such activity by the federal branch; (3) Is... study, management plan, financial projections, business plan, or similar document concerning the conduct...

  10. Differential activation of the HCO3− conductance through the cystic fibrosis transmembrane conductance regulator anion channel by genistein and forskolin in murine duodenum

    PubMed Central

    Tuo, Biguang; Wen, Guorong; Seidler, Ursula

    2009-01-01

    Background and purpose: Many cystic fibrosis (CF)-associated mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) anion channels affect CFTR-activated HCO3− transport more than Cl− transport. Targeting the CFTR HCO3− conductance, if possible, may therefore be of major therapeutic benefit. In the present study, we examined the effects of genistein and forskolin on duodenal mucosal HCO3− and Cl− secretion. Experimental approach: Murine duodenal mucosal HCO3− and Cl− secretions were examined in vitro in Ussing chambers by the pH stat and short circuit current (Isc) techniques. Key results: Genistein markedly stimulated duodenal HCO3− secretion and Isc in a dose-dependent manner in CFTR wild-type mice, but not in CFTR null mice. CFTRinh-172, a highly specific CFTR inhibitor, inhibited genistein-stimulated duodenal HCO3− secretion and Isc in wild-type mice. Genistein induced 59% net HCO3− increase and 123% net Isc increase over basal value, whereas forskolin, an activator of adenylate cyclase, induced 94% net HCO3− increase and 507% net Isc increase, indicating that, compared with forskolin, genistein induced a relatively high HCO3−/Isc ratio. Further data showed that CFTR HCO3−/Cl− conductance ratio was 1.05 after genistein stimulation, whereas after forskolin stimulation, the CFTR HCO3−/Cl− conductance ratio was 0.27. Conclusions and implications: Genistein stimulates duodenal HCO3− and Cl− secretion through CFTR, and has a relatively high selectivity for the CFTR HCO3− conductance, compared with forskolin. This may indicate the feasibility of selective targeting of the HCO3− conductance of the CFTR channels. PMID:19788494

  11. Nespoli conducts a test run with the French/CNES Neuroscientific Research Experiment

    NASA Image and Video Library

    2011-02-12

    ISS026-E-027000 (12 Feb. 2011) --- European Space Agency (ESA) astronaut Paolo Nespoli, Expedition 26 flight engineer, conducts a test run with the French/CNES neuroscientific research experiment ?3D-Space? (SAP) in the Columbus laboratory of the International Space Station. While floating freely, Nespoli used the ESA multipurpose laptop with a prepared hard disk drive, data storage on a memory card, and an electronic pen table connected to it. 3D-Space, which involves distance, writing and illusion exercises, is designed to test the hypothesis that altered visual perception affects motor control.

  12. An annotated bibliography of scientific literature on research and management activities conducted in Coram Experimental Forest

    Treesearch

    Ilana Abrahamson; Katie Lyon

    2012-01-01

    The Coram Experimental Forest represents western larch-mixed conifer forests of the Northern Rockies. Western larch research was centered at Coram Experimental Forest (CEF) to provide a scientific basis to regenerate and grow this important and valuable species. For example, the long-term silvicultural studies installed at CEF are allowing researchers and managers to...

  13. Comparative research on activation technique for GaAs photocathodes

    NASA Astrophysics Data System (ADS)

    Chen, Liang; Qian, Yunsheng; Chang, Benkang; Chen, Xinlong; Yang, Rui

    2012-03-01

    The properties of GaAs photocathodes mainly depend on the material design and activation technique. In early researches, high-low temperature two-step activation has been proved to get more quantum efficiency than high-temperature single-step activation. But the variations of surface barriers for two activation techniques have not been well studied, thus the best activation temperature, best Cs-O ratio and best activation time for two-step activation technique have not been well found. Because the surface photovoltage spectroscopy (SPS) before activation is only in connection with the body parameters for GaAs photocathode such as electron diffusion length and the spectral response current (SRC) after activation is in connection with not only body parameters but also surface barriers, thus the surface escape probability (SEP) can be well fitted through the comparative research between SPS before activation and SEP after activation. Through deduction for the tunneling process of surface barriers by Schrödinger equation, the width and height for surface barrier I and II can be well fitted through the curves of SEP. The fitting results were well proved and analyzed by quantitative analysis of angle-dependent X-ray photoelectron spectroscopy (ADXPS) which can also study the surface chemical compositions, atomic concentration percentage and layer thickness for GaAs photocathodes. This comparative research method for fitting parameters of surface barriers through SPS before activation and SRC after activation shows a better real-time in system method for the researches of activation techniques.

  14. The conduct of Australian Indigenous primary health care research focusing on social and emotional wellbeing: a systematic review.

    PubMed

    Farnbach, Sara; Eades, Anne-Maree; Gwynn, Josephine D; Glozier, Nick; Hackett, Maree L

    2018-06-14

    Objectives and importance of study: Values and ethics: guidelines for ethical conduct in Aboriginal and Torres Strait Islander health research (Values and ethics) describes key values that should underpin Aboriginal and Torres Strait Islander (Indigenous)-focused health research. It is unclear how research teams address this document in primary health care research. We systematically review the primary health care literature focusing on Indigenous social and emotional wellbeing (SEWB) to identify how Values and ethics and community preferences for standards of behaviour (local protocols) are addressed during research. Systematic review in accordance with PRISMA Guidelines and MOOSE Guidelines for Meta-Analyses and Systematic Reviews of Observational Studies. We searched four databases and one Indigenous-specific website for qualitative, quantitative and mixed-method studies published since Values and ethics was implemented (2003). Included studies were conducted in primary health care services, focused on Indigenous SEWB and were conducted by research teams. Using standard data extraction forms, we identified actions taken (reported by authors or identified by us) relating to Values and ethics and local protocols. A total of 25 studies were included. Authors of two studies explicitly mentioned the Values and ethics document, but neither reported how their actions related to the document's values. In more than half the studies, we identified at least three actions relating to the values. Some actions related to multiple values, including use of culturally sensitive research processes and involving Indigenous representatives in the research team. Local protocols were rarely reported. Addressing Values and ethics appears to improve research projects. The academic community should focus on culturally sensitive research processes, relationship building and developing the Indigenous research workforce, to facilitate acceptable research that affects health outcomes. For

  15. 10 CFR 745.103 - Assuring compliance with this policy-research conducted or supported by any Federal department or...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... PROTECTION OF HUMAN SUBJECTS § 745.103 Assuring compliance with this policy—research conducted or supported... file with the Office for Human Research Protections, HHS, or any successor office, and approved for... department and agency heads shall also be made to the Office for Human Research Protections, HHS, or any...

  16. 45 CFR 690.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... proposals for research to be conducted or supported by a Federal department or agency. 690.120 Section 690... PROTECTION OF HUMAN SUBJECTS § 690.120 Evaluation and disposition of applications and proposals for research... evaluate all applications and proposals involving human subjects submitted to the department or agency...

  17. Instruction in the Responsible Conduct of Research: An Inventory of Programs and Materials within CTSAs

    PubMed Central

    DuBois, James M.; Schilling, Debie A.; Heitman, Elizabeth; Steneck, Nicholas H.; Kon, Alexander A.

    2010-01-01

    Abstract The National Institutes of Health (NIH) require instruction in the responsible conduct of research (RCR) as a component of any Clinical and Translational Science Award (CTSA). The Educational Materials Group of the NIH CTSA Consortium's Clinical Research Ethics Key Function Committee (CRE‐KFC) conducted a survey of the 38 institutions that held CTSA funding as of January 2009 to determine how they satisfy RCR training requirements. An 8‐item questionnaire was sent by email to directors of the Clinical Research Ethics, the Educational and Career Development, and the Regulatory Knowledge cores. We received 78 completed surveys from 38 CTSAs (100%). We found that there is no unified approach to RCR training across CTSAs, many programs lack a coherent plan for RCR instruction, and most CTSAs have not developed unique instructional materials tailored to the needs of clinical and translational scientists. We recommend collaboration among CTSAs and across CTSA key function committees to address these weaknesses. We also requested that institutions send electronic copies of original RCR training materials to share among CTSAs via the CTSpedia website. Twenty institutions submitted at least one educational product. The CTSpedia now contains more than 90 RCR resources. PMID:20590680

  18. Instruction in the responsible conduct of research: an inventory of programs and materials within CTSAs.

    PubMed

    DuBois, James M; Schilling, Debie A; Heitman, Elizabeth; Steneck, Nicholas H; Kon, Alexander A

    2010-06-01

    The National Institutes of Health (NIH) require instruction in the responsible conduct of research (RCR) as a component of any Clinical and Translational Science Award (CTSA). The Educational Materials Group of the NIH CTSA Consortium's Clinical Research Ethics Key Function Committee (CRE-KFC) conducted a survey of the 38 institutions that held CTSA funding as of January 2009 to determine how they satisfy RCR training requirements. An 8-item questionnaire was sent by email to directors of the Clinical Research Ethics, the Educational and Career Development, and the Regulatory Knowledge cores. We received 78 completed surveys from 38 CTSAs (100%). We found that there is no unified approach to RCR training across CTSAs, many programs lack a coherent plan for RCR instruction, and most CTSAs have not developed unique instructional materials tailored to the needs of clinical and translational scientists. We recommend collaboration among CTSAs and across CTSA key function committees to address these weaknesses. We also requested that institutions send electronic copies of original RCR training materials to share among CTSAs via the CTSpedia website. Twenty institutions submitted at least one educational product. The CTSpedia now contains more than 90 RCR resources.

  19. Active pore space utilization in nanoporous carbon-based supercapacitors: Effects of conductivity and pore accessibility

    NASA Astrophysics Data System (ADS)

    Seredych, Mykola; Koscinski, Mikolaj; Sliwinska-Bartkowiak, Malgorzata; Bandosz, Teresa J.

    2012-12-01

    Composites of commercial graphene and nanoporous sodium-salt-polymer-derived carbons were prepared with 5 or 20 weight% graphene. The materials were characterized using the adsorption of nitrogen, SEM/EDX, thermal analysis, Raman spectroscopy and potentiometric titration. The samples' conductivity was also measured. The performance of the carbon composites in energy storage was linked to their porosity and electronic conductivity. The small pores (<0.7) were found as very active for double layer capacitance. It was demonstrated that when double layer capacitance is a predominant mechanism of charge storage, the degree of the pore space utilization for that storage can be increased by increasing the conductivity of the carbons. That active pore space utilization is defined as gravimetric capacitance per unit pore volume in pores smaller than 0.7 nm. Its magnitude is affected by conductivity of the carbon materials. The functional groups, besides pseudocapacitive contribution, increased the wettability and thus the degree of the pore space utilization. Graphene phase, owing to its conductivity, also took part in an insitu increase of the small pore accessibility and thus the capacitance of the composites via enhancing an electron transfer to small pores and thus imposing the reduction of groups blocking the pores for electrolyte ions.

  20. Developing a research agenda for promoting physical activity in Brazil through environmental and policy change.

    PubMed

    Reis, Rodrigo S; Kelly, Cheryl M; Parra, Diana C; Barros, Mauro; Gomes, Grace; Malta, Deborah; Schmid, Thomas; Brownson, Ross C

    2012-08-01

    To identify the highest priorities for research on environmental and policy changes for promoting physical activity (PA) in Brazil; to uncover any gaps between researchers' and practitioners' priorities; and to consider which tools, methods, collaborative strategies, and actions could be useful to moving a research agenda forward. This was a mixed-methods study (qualitative and quantitative) conducted by Project GUIA (Guide for Useful Interventions for Activity in Brazil and Latin America) in February 2010-January 2011. A total of 240 individuals in the PA field (186 practitioners and 54 researchers) were asked to generate research ideas; 82 participants provided 266 original statements from which 52 topics emerged. Participants rated topics by "importance" and "feasibility;" a separate convenience sample of 21 individuals categorized them. Cluster analysis and multidimensional scaling were used to create concept maps and pattern matches. Five distinct clusters emerged from the concept mapping, of which "effectiveness and innovation in PA interventions" was rated most important by both practitioners and researchers. Pattern matching showed a divergence between the groups, especially regarding feasibility, where there was no consensus. The study results provided the basis for a research agenda to advance the understanding of environmental and policy influences on PA promotion in Brazil and Latin America. These results should stimulate future research and, ultimately, contribute to the evidence-base of successful PA strategies in Latin America.