Sample records for activity requires knowledge

  1. 49 CFR 383.111 - Required knowledge.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 5 2011-10-01 2011-10-01 false Required knowledge. 383.111 Section 383.111... STANDARDS; REQUIREMENTS AND PENALTIES Required Knowledge and Skills § 383.111 Required knowledge. (a) All CMV operators must have knowledge of the following 20 general areas: (1) Safe operations regulations...

  2. 49 CFR 383.111 - Required knowledge.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Required knowledge. 383.111 Section 383.111... STANDARDS; REQUIREMENTS AND PENALTIES Required Knowledge and Skills § 383.111 Required knowledge. All commercial motor vehicle operators must have knowledge of the following general areas: (a) Safe operations...

  3. 14 CFR 63.53 - Knowledge requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Knowledge requirements. 63.53 Section 63.53 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: FLIGHT CREWMEMBERS OTHER THAN PILOTS Flight Navigators § 63.53 Knowledge requirements. (a) An...

  4. 14 CFR 65.75 - Knowledge requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Knowledge requirements. 65.75 Section 65.75 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: AIRMEN OTHER THAN FLIGHT CREWMEMBERS Mechanics § 65.75 Knowledge requirements. (a) Each applicant...

  5. 14 CFR 65.75 - Knowledge requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Knowledge requirements. 65.75 Section 65.75 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: AIRMEN OTHER THAN FLIGHT CREWMEMBERS Mechanics § 65.75 Knowledge requirements. (a) Each applicant...

  6. 14 CFR 65.55 - Knowledge requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Knowledge requirements. 65.55 Section 65.55 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: AIRMEN OTHER THAN FLIGHT CREWMEMBERS Aircraft Dispatchers § 65.55 Knowledge requirements. (a) A...

  7. 14 CFR 63.53 - Knowledge requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Knowledge requirements. 63.53 Section 63.53 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: FLIGHT CREWMEMBERS OTHER THAN PILOTS Flight Navigators § 63.53 Knowledge requirements. (a) An...

  8. 14 CFR 63.35 - Knowledge requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Knowledge requirements. 63.35 Section 63.35 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: FLIGHT CREWMEMBERS OTHER THAN PILOTS Flight Engineers § 63.35 Knowledge requirements. (a) An...

  9. What Math Knowledge Does Teaching Require?

    ERIC Educational Resources Information Center

    Thames, Mark Hoover; Ball, Deborah Loewenberg

    2010-01-01

    No one would argue with the claim that teaching mathematics requires mathematics knowledge. However, a clear description of such knowledge needed for teaching has been surprisingly elusive. To differentiate teachers' levels of mathematical knowledge, numerous studies have examined whether a teacher has a certification in math or a degree as well…

  10. Activating Event Knowledge

    ERIC Educational Resources Information Center

    Hare, Mary; Jones, Michael; Thomson, Caroline; Kelly, Sarah; McRae, Ken

    2009-01-01

    An increasing number of results in sentence and discourse processing demonstrate that comprehension relies on rich pragmatic knowledge about real-world events, and that incoming words incrementally activate such knowledge. If so, then even outside of any larger context, nouns should activate knowledge of the generalized events that they denote or…

  11. Active-learning strategies to develop health literacy knowledge and skills.

    PubMed

    Devraj, Radhika; Butler, Lakesha M; Gupchup, Gireesh V; Poirier, Therese I

    2010-10-11

    To implement active-learning exercises in a required pharmacy course and assess their impact on students' knowledge and confidence in identifying and communicating with patients with low health literacy, as part of a required course in cultural competency, health literacy, and health beliefs. Active-learning activities including administering health literacy assessments, identifying informal signs of low health literacy, conducting mock patient counseling sessions, rating the readability of drug information, analyzing information in drug advertisements, and writing patient education materials were incorporated into the 6-sesssion health literacy portion of the course. A pretest and posttest showed that students' knowledge of health literacy increased, and a retrospective pretest found improvement in students' confidence in their ability to care for patients with low health literacy. In-class discussions provided informal evidence that students gained new knowledge from the active-learning activities. The addition of active-learning activities was effective in teaching health literacy concepts to pharmacy students.

  12. 14 CFR 65.75 - Knowledge requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... CERTIFICATION: AIRMEN OTHER THAN FLIGHT CREWMEMBERS Mechanics § 65.75 Knowledge requirements. (a) Each applicant for a mechanic certificate or rating must, after meeting the applicable experience requirements of...

  13. 14 CFR 65.75 - Knowledge requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CERTIFICATION: AIRMEN OTHER THAN FLIGHT CREWMEMBERS Mechanics § 65.75 Knowledge requirements. (a) Each applicant for a mechanic certificate or rating must, after meeting the applicable experience requirements of...

  14. 14 CFR 65.75 - Knowledge requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CERTIFICATION: AIRMEN OTHER THAN FLIGHT CREWMEMBERS Mechanics § 65.75 Knowledge requirements. (a) Each applicant for a mechanic certificate or rating must, after meeting the applicable experience requirements of...

  15. 14 CFR 65.35 - Knowledge requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Knowledge requirements. 65.35 Section 65.35 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: AIRMEN OTHER THAN FLIGHT CREWMEMBERS Air Traffic Control Tower Operators § 65.35 Knowledge...

  16. 14 CFR 65.35 - Knowledge requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Knowledge requirements. 65.35 Section 65.35 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: AIRMEN OTHER THAN FLIGHT CREWMEMBERS Air Traffic Control Tower Operators § 65.35 Knowledge...

  17. Knowledge-based requirements analysis for automating software development

    NASA Technical Reports Server (NTRS)

    Markosian, Lawrence Z.

    1988-01-01

    We present a new software development paradigm that automates the derivation of implementations from requirements. In this paradigm, informally-stated requirements are expressed in a domain-specific requirements specification language. This language is machine-understable and requirements expressed in it are captured in a knowledge base. Once the requirements are captured, more detailed specifications and eventually implementations are derived by the system using transformational synthesis. A key characteristic of the process is that the required human intervention is in the form of providing problem- and domain-specific engineering knowledge, not in writing detailed implementations. We describe a prototype system that applies the paradigm in the realm of communication engineering: the prototype automatically generates implementations of buffers following analysis of the requirements on each buffer.

  18. Gamete activation: basic knowledge and clinical applications

    PubMed Central

    Tosti, Elisabetta; Ménézo, Yves

    2016-01-01

    Background The first clues to the process of gamete activation date back to nearly 60 years ago. The mutual activation of gametes is a crucial event during fertilization. In the testis and ovaries, spermatozoa and oocytes are in a state of meiotic and metabolic quiescence and require reciprocal signals in order to undergo functional changes that lead to competence for fertilization. First, the oocyte activates sperm by triggering motility, chemoattraction, binding and the acrosome reaction, culminating with the fusion of the two plasma membranes. At the end of this cascade of events, collectively known as sperm capacitation, sperm-induced oocyte activation occurs, generating electrical, morphological and metabolic modifications in the oocyte. Objective and rationale The aim of this review is to provide the current state of knowledge regarding the entire process of gamete activation in selected specific animal models that have contributed to our understanding of fertilization in mammals, including humans. Here we describe in detail the reciprocal induction of the two activation processes, the molecules involved and the mechanisms of cell interaction and signal transduction that ultimately result in successful embryo development and creation of a new individual. Search methods We carried out a literature survey with no restrictions on publication date (from the early 1950s to March 2016) using PubMed/Medline, Google Scholar and Web of Knowledge by utilizing common keywords applied in the field of fertilization and embryo development. We also screened the complete list of references published in the most recent research articles and relevant reviews published in English (both animal and human studies) on the topics investigated. Outcomes Literature on the principal animal models demonstrates that gamete activation is a pre-requisite for successful fertilization, and is a process common to all species studied to date. We provide a detailed description of the dramatic

  19. 14 CFR 65.55 - Knowledge requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Knowledge requirements. 65.55 Section 65.55 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN...) General system of weather and NOTAM collection, dissemination, interpretation, and use; (4) Interpretation...

  20. 14 CFR 65.55 - Knowledge requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Knowledge requirements. 65.55 Section 65.55 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN...) General system of weather and NOTAM collection, dissemination, interpretation, and use; (4) Interpretation...

  1. 14 CFR 65.35 - Knowledge requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Knowledge requirements. 65.35 Section 65.35 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN... assistance service; (f) Air navigation, and aids to air navigation; and (g) Aviation weather. ...

  2. 14 CFR 65.35 - Knowledge requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Knowledge requirements. 65.35 Section 65.35 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN... assistance service; (f) Air navigation, and aids to air navigation; and (g) Aviation weather. ...

  3. 14 CFR 65.35 - Knowledge requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Knowledge requirements. 65.35 Section 65.35 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN... assistance service; (f) Air navigation, and aids to air navigation; and (g) Aviation weather. ...

  4. 14 CFR 63.53 - Knowledge requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., including flight planning and cruise control; (3) Practical meteorology, including analysis of weather maps... CERTIFICATION: FLIGHT CREWMEMBERS OTHER THAN PILOTS Flight Navigators § 63.53 Knowledge requirements. (a) An applicant for a flight navigator certificate must pass a written test on— (1) The regulations of this...

  5. 14 CFR 63.53 - Knowledge requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., including flight planning and cruise control; (3) Practical meteorology, including analysis of weather maps... CERTIFICATION: FLIGHT CREWMEMBERS OTHER THAN PILOTS Flight Navigators § 63.53 Knowledge requirements. (a) An applicant for a flight navigator certificate must pass a written test on— (1) The regulations of this...

  6. 14 CFR 63.53 - Knowledge requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., including flight planning and cruise control; (3) Practical meteorology, including analysis of weather maps... CERTIFICATION: FLIGHT CREWMEMBERS OTHER THAN PILOTS Flight Navigators § 63.53 Knowledge requirements. (a) An applicant for a flight navigator certificate must pass a written test on— (1) The regulations of this...

  7. 49 CFR 383.111 - Required knowledge.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 5 2013-10-01 2013-10-01 false Required knowledge. 383.111 Section 383.111... safe vehicle operations; (iii) The effects of fatigue, poor vision, hearing impairment, and general..., off tracking, right/left turns and right curves. (5) Shifting. The basic shifting rules and terms for...

  8. 49 CFR 383.111 - Required knowledge.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 5 2012-10-01 2012-10-01 false Required knowledge. 383.111 Section 383.111... safe vehicle operations; (iii) The effects of fatigue, poor vision, hearing impairment, and general..., off tracking, right/left turns and right curves. (5) Shifting. The basic shifting rules and terms for...

  9. 49 CFR 383.111 - Required knowledge.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 5 2014-10-01 2014-10-01 false Required knowledge. 383.111 Section 383.111... safe vehicle operations; (iii) The effects of fatigue, poor vision, hearing impairment, and general..., off tracking, right/left turns and right curves. (5) Shifting. The basic shifting rules and terms for...

  10. The relationship between chiropractor required and current level of business knowledge.

    PubMed

    Ciolfi, Michael Anthony; Kasen, Patsy Anne

    2017-01-01

    Chiropractors frequently practice within health care systems requiring the business acumen of an entrepreneur. However, some chiropractors do not know the relationship between the level of business knowledge required for practice success and their current level of business knowledge. The purpose of this quantitative study was to examine the relationship between chiropractors' perceived level of business knowledge required and their perceived level of current business knowledge. Two hundred and seventy-four participants completed an online survey (Health Care Training and Education Needs Survey) which included eight key business items. Participants rated the level of perceived business knowledge required (Part I) and their current perceived level of knowledge (Part II) for the same eight items. Data was collected from November 27, 2013 to December 18, 2013. Data were analyzed using Spearman's ranked correlation to determine the statistically significant relationships for the perceived level of knowledge required and the perceived current level of knowledge for each of the paired eight items from Parts I and II of the survey. Wilcoxon Signed Ranks Tests were performed to determine the statistical difference between the paired items. The results of Spearman's correlation testing indicated a statistically significant ( p < 0.01) positive correlation for the perceived level of knowledge required and perceived current level of knowledge for six variables: (a) organizational behavior, (b) strategic management, (c) marketing, (d) legal and ethical, (e) managerial decisions, and (f) operations. Wilcoxon Signed Ranks testing indicated a significant difference for three paired items: strategic management; marketing and; legal and ethical. The results suggest that relationships exist for the majority of business items (6 of 8) however a statistically difference was demonstrated in only three of the paired business items. The implications of this study for social change include

  11. Access to finance from different finance provider types: Farmer knowledge of the requirements.

    PubMed

    Wulandari, Eliana; Meuwissen, Miranda P M; Karmana, Maman H; Oude Lansink, Alfons G J M

    2017-01-01

    Analysing farmer knowledge of the requirements of finance providers can provide valuable insights to policy makers about ways to improve farmers' access to finance. This study compares farmer knowledge of the requirements to obtain finance with the actual requirements set by different finance provider types, and investigates the relation between demographic and socioeconomic factors and farmer knowledge of finance requirements. We use a structured questionnaire to collect data from a sample of finance providers and farmers in Java Island, Indonesia. We find that the most important requirements to acquire finance vary among different finance provider types. We also find that farmers generally have little knowledge of the requirements, which are important to each type of finance provider. Awareness campaigns are needed to increase farmer knowledge of the diversity of requirements among the finance provider types.

  12. Requirements analysis, domain knowledge, and design

    NASA Technical Reports Server (NTRS)

    Potts, Colin

    1988-01-01

    Two improvements to current requirements analysis practices are suggested: domain modeling, and the systematic application of analysis heuristics. Domain modeling is the representation of relevant application knowledge prior to requirements specification. Artificial intelligence techniques may eventually be applicable for domain modeling. In the short term, however, restricted domain modeling techniques, such as that in JSD, will still be of practical benefit. Analysis heuristics are standard patterns of reasoning about the requirements. They usually generate questions of clarification or issues relating to completeness. Analysis heuristics can be represented and therefore systematically applied in an issue-based framework. This is illustrated by an issue-based analysis of JSD's domain modeling and functional specification heuristics. They are discussed in the context of the preliminary design of simple embedded systems.

  13. Access to finance from different finance provider types: Farmer knowledge of the requirements

    PubMed Central

    Meuwissen, Miranda P. M.; Karmana, Maman H.; Oude Lansink, Alfons G. J. M.

    2017-01-01

    Analysing farmer knowledge of the requirements of finance providers can provide valuable insights to policy makers about ways to improve farmers’ access to finance. This study compares farmer knowledge of the requirements to obtain finance with the actual requirements set by different finance provider types, and investigates the relation between demographic and socioeconomic factors and farmer knowledge of finance requirements. We use a structured questionnaire to collect data from a sample of finance providers and farmers in Java Island, Indonesia. We find that the most important requirements to acquire finance vary among different finance provider types. We also find that farmers generally have little knowledge of the requirements, which are important to each type of finance provider. Awareness campaigns are needed to increase farmer knowledge of the diversity of requirements among the finance provider types. PMID:28877174

  14. Invisible Brain: Knowledge in Research Works and Neuron Activity.

    PubMed

    Segev, Aviv; Curtis, Dorothy; Jung, Sukhwan; Chae, Suhyun

    2016-01-01

    If the market has an invisible hand, does knowledge creation and representation have an "invisible brain"? While knowledge is viewed as a product of neuron activity in the brain, can we identify knowledge that is outside the brain but reflects the activity of neurons in the brain? This work suggests that the patterns of neuron activity in the brain can be seen in the representation of knowledge-related activity. Here we show that the neuron activity mechanism seems to represent much of the knowledge learned in the past decades based on published articles, in what can be viewed as an "invisible brain" or collective hidden neural networks. Similar results appear when analyzing knowledge activity in patents. Our work also tries to characterize knowledge increase as neuron network activity growth. The results propose that knowledge-related activity can be seen outside of the neuron activity mechanism. Consequently, knowledge might exist as an independent mechanism.

  15. Invisible Brain: Knowledge in Research Works and Neuron Activity

    PubMed Central

    Segev, Aviv; Curtis, Dorothy; Jung, Sukhwan; Chae, Suhyun

    2016-01-01

    If the market has an invisible hand, does knowledge creation and representation have an “invisible brain”? While knowledge is viewed as a product of neuron activity in the brain, can we identify knowledge that is outside the brain but reflects the activity of neurons in the brain? This work suggests that the patterns of neuron activity in the brain can be seen in the representation of knowledge-related activity. Here we show that the neuron activity mechanism seems to represent much of the knowledge learned in the past decades based on published articles, in what can be viewed as an “invisible brain” or collective hidden neural networks. Similar results appear when analyzing knowledge activity in patents. Our work also tries to characterize knowledge increase as neuron network activity growth. The results propose that knowledge-related activity can be seen outside of the neuron activity mechanism. Consequently, knowledge might exist as an independent mechanism. PMID:27439199

  16. The study on knowledge transferring incentive for information system requirement development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Yang

    2015-03-10

    Information system requirement development is a process of users’ knowledge sharing and transferring. However the tacit requirements developing is a main problem during requirement development process, for the reason of difficult to encoding, express, and communicate. Knowledge fusion and corporate effort is needed to finding tacit requirements. Under this background, our paper try to find out the rule of effort dynamic evolutionary of software developer and user by building an evolutionary game model on the condition of incentive system. And in addition this paper provides an in depth discussion at the end of this paper.

  17. Excellence in clinical teaching: knowledge transformation and development required.

    PubMed

    Irby, David M

    2014-08-01

    Clinical teachers in medicine face the daunting task of mastering the many domains of knowledge needed for practice and teaching. The breadth and complexity of this knowledge continue to increase, as does the difficulty of transforming the knowledge into concepts that are understandable to learners. Properly targeted faculty development has the potential to expedite the knowledge transformation process for clinical teachers. Based on my own research in clinical teaching and faculty development, as well as the work of others, I describe the unique forms of clinical teacher knowledge, the transformation of that knowledge for teaching purposes and implications for faculty development. The following forms of knowledge for clinical teaching in medicine need to be mastered and transformed: (i) knowledge of medicine and patients; (ii) knowledge of context; (iii) knowledge of pedagogy and learners, and (iv) knowledge integrated into teaching scripts. This knowledge is employed and conveyed through the parallel processes of clinical reasoning and clinical instructional reasoning. Faculty development can facilitate this knowledge transformation process by: (i) examining, deconstructing and practising new teaching scripts; (ii) focusing on foundational concepts; (iii) demonstrating knowledge-in-use, and (iv) creating a supportive organisational climate for clinical teaching. To become an excellent clinical teacher in medicine requires the transformation of multiple forms of knowledge for teaching purposes. These domains of knowledge allow clinical teachers to provide tailored instruction to learners at varying levels in the context of fast-paced and demanding clinical practice. Faculty development can facilitate this knowledge transformation process. © 2014 John Wiley & Sons Ltd.

  18. Physical Activity Participation and Nutrition and Physical Activity Knowledge in University Dance Students.

    PubMed

    Hanna, Katherine; Hanley, Anne; Huddy, Avril; McDonald, Michael; Willer, Fiona

    2017-03-01

    To assess participation in physical activity and knowledge of general nutrition and current public health messages about the health benefits of physical activity in university dance students, and to investigate differences between first-year and later-year students and between students in dance and dance performance course groups. This cross-sectional study recruited 67 participants from dance undergraduate degrees in a university in Australia. Nutrition knowledge was assessed using the General Nutrition Knowledge Questionnaire. Physical activity participation and awareness of its benefits were assessed using the Active Australia Survey. Results indicate low nutrition knowledge among dance students, with 47% and 52% of responses correct in dance and dance performance students, respectively. Nutrition knowledge did not vary between students in first or later years. Self-reported participation in moderate and vigorous physical activity varied substantially and met or exceeded recommendations based upon duration and frequency for 98% of participants. However, awareness of physical activity messages varied, with dance students more likely to disagree about the level of activity needed for health benefits. Dance students report varying levels of physical activity that usually met or exceeded recommendations; however, knowledge of general nutrition and physical activity benefits was low. Improved knowledge could contribute to changes in behavior that improve health status in this population.

  19. The influence of prior knowledge on the retrieval-directed function of note taking in prior knowledge activation.

    PubMed

    Wetzels, Sandra A J; Kester, Liesbeth; van Merriënboer, Jeroen J G; Broers, Nick J

    2011-06-01

    Prior knowledge activation facilitates learning. Note taking during prior knowledge activation (i.e., note taking directed at retrieving information from memory) might facilitate the activation process by enabling learners to build an external representation of their prior knowledge. However, taking notes might be less effective in supporting prior knowledge activation if available prior knowledge is limited. This study investigates the effects of the retrieval-directed function of note taking depending on learners' level of prior knowledge. It is hypothesized that the effectiveness of note taking is influenced by the amount of prior knowledge learners already possess. Sixty-one high school students participated in this study. A prior knowledge test was used to ascertain differences in level of prior knowledge and assign participants to a low or a high prior knowledge group. A 2×2 factorial design was used to investigate the effects of note taking during prior knowledge activation (yes, no) depending on learners' level of prior knowledge (low, high) on mental effort, performance, and mental efficiency. Note taking during prior knowledge activation lowered mental effort and increased mental efficiency for high prior knowledge learners. For low prior knowledge learners, note taking had the opposite effect on mental effort and mental efficiency. The effects of the retrieval-directed function of note taking are influenced by learners' level of prior knowledge. Learners with high prior knowledge benefit from taking notes while activating prior knowledge, whereas note taking has no beneficial effects for learners with limited prior knowledge. ©2010 The British Psychological Society.

  20. Representation and presentation of requirements knowledge

    NASA Technical Reports Server (NTRS)

    Johnson, W. L.; Feather, Martin S.; Harris, David R.

    1992-01-01

    An approach to representation and presentation of knowledge used in the ARIES, an experimental requirements/specification environment, is described. The approach applies the notion of a representation architecture to the domain of software engineering and incorporates a strong coupling to a transformation system. It is characterized by a single highly expressive underlying representation, interfaced simultaneously to multiple presentations, each with notations of differing degrees of expressivity. This enables analysts to use multiple languages for describing systems and have these descriptions yield a single consistent model of the system.

  1. Animal Related Activities as Determinants of Species Knowledge

    ERIC Educational Resources Information Center

    Randler, Christoph

    2010-01-01

    Previous work has established a relationship between knowledge and environmental concern. Different factors may contribute to this knowledge and animal-related leisure activities may also contribute to this knowledge. 390 participants in Leipzig, Germany were interviewed to assess their animal-related leisure activities, their demographic status…

  2. 46 CFR 11.713 - Requirements for maintaining current knowledge of waters to be navigated.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Requirements for maintaining current knowledge of waters... § 11.713 Requirements for maintaining current knowledge of waters to be navigated. (a) If a first class... current knowledge of the route. Persons using this method of re-familiarization shall certify, when...

  3. Lack of knowledge of physical activity guidelines: can physical activity promotion campaigns do better?

    PubMed

    Knox, Emily C L; Esliger, Dale W; Biddle, Stuart J H; Sherar, Lauren B

    2013-12-05

    To identify the prevalence of knowledge of the current UK physical activity guidelines which were introduced in 2011 and prior physical activity guidelines (30 min on 5 days each week) within two large samples of UK adult's. To investigate whether knowledge of physical activity guidelines differs according to demographics such as ethnicity, age, education and employment status. Descriptive cross-sectional study comparing two distinctive adult samples. National survey and online-administered survey conducted in England. The 2007 Health Survey for England provides data on knowledge of physical activity guidelines from 2860 UK adults (56% women, 89% white, 63% under 45 years old). In 2013, an online survey was disseminated and data were collected from 1797 UK adults on knowledge of the most recent physical activity guidelines. The 2013 sample was 70% women, 92% white and 57% under 45 years old. All adults in both samples were >18 years old and without illnesses/disorders likely to restrict physical activity. Knowledge of physical activity guidelines in 2007 and 2013. Demographic correlates of knowledge of moderate-to-vigorous physical activity guidelines. 18% of the 2013 sample accurately recalled the current physical activity guidelines compared with 11% of the 2007 sample who accurately recalled the previous guidelines. The differences in knowledge of physical activity guidelines existed for marital status, gender, age, education and employment status within both 2007 and 2013 samples (p<0.05). Men with lower education and employment status (unemployed including student and retired) and older adults were less likely to know physical activity guidelines (p<0.05). Knowledge of physical activity guidelines remained higher in the 2013 sample after controlling for demographic differences (p<0.05). Disadvantaged population groups are less knowledgeable about physical activity guidelines. Although knowledge of physical activity guidelines appears to have increased in

  4. Some requirements and suggestions for a methodology to develop knowledge based systems.

    PubMed

    Green, D W; Colbert, M; Long, J

    1989-11-01

    This paper describes an approach to the creation of a methodology for the development of knowledge based systems. It specifies some requirements and suggests how these requirements might be met. General requirements can be satisfied using a systems approach. More specific ones can be met by viewing an organization as a network of consultations for coordinating expertise. The nature of consultations is described and the form of a possible cognitive model using a blackboard architecture is outlined. The value of the approach is illustrated in terms of certain knowledge elicitation methods.

  5. Course Ontology-Based User's Knowledge Requirement Acquisition from Behaviors within E-Learning Systems

    ERIC Educational Resources Information Center

    Zeng, Qingtian; Zhao, Zhongying; Liang, Yongquan

    2009-01-01

    User's knowledge requirement acquisition and analysis are very important for a personalized or user-adaptive learning system. Two approaches to capture user's knowledge requirement about course content within an e-learning system are proposed and implemented in this paper. The first approach is based on the historical data accumulated by an…

  6. Architecture and Initial Development of a Knowledge-as-a-Service Activator for Computable Knowledge Objects for Health.

    PubMed

    Flynn, Allen J; Boisvert, Peter; Gittlen, Nate; Gross, Colin; Iott, Brad; Lagoze, Carl; Meng, George; Friedman, Charles P

    2018-01-01

    The Knowledge Grid (KGrid) is a research and development program toward infrastructure capable of greatly decreasing latency between the publication of new biomedical knowledge and its widespread uptake into practice. KGrid comprises digital knowledge objects, an online Library to store them, and an Activator that uses them to provide Knowledge-as-a-Service (KaaS). KGrid's Activator enables computable biomedical knowledge, held in knowledge objects, to be rapidly deployed at Internet-scale in cloud computing environments for improved health. Here we present the Activator, its system architecture and primary functions.

  7. The Influence of Prior Knowledge on the Retrieval-Directed Function of Note Taking in Prior Knowledge Activation

    ERIC Educational Resources Information Center

    Wetzels, Sandra A. J.; Kester, Liesbeth; van Merrienboer, Jeroen J. G.; Broers, Nick J.

    2011-01-01

    Background: Prior knowledge activation facilitates learning. Note taking during prior knowledge activation (i.e., note taking directed at retrieving information from memory) might facilitate the activation process by enabling learners to build an external representation of their prior knowledge. However, taking notes might be less effective in…

  8. Generalized event knowledge activation during online sentence comprehension

    PubMed Central

    Metusalem, Ross; Kutas, Marta; Urbach, Thomas P.; Hare, Mary; McRae, Ken; Elman, Jeffrey L.

    2012-01-01

    Recent research has demonstrated that knowledge of real-world eventsplays an important role inguiding online language comprehension. The present study addresses the scope of event knowledge activation during the course of comprehension, specifically investigating whether activation is limited to those knowledge elements that align with the local linguistic context.The present study addresses this issue by analyzing event-related brain potentials (ERPs) recorded as participants read brief scenariosdescribing typical real-world events. Experiment 1 demonstratesthat a contextually anomalous word elicits a reduced N400 if it is generally related to the described event, even when controlling for the degree of association of this word with individual words in the preceding context and with the expected continuation. Experiment 2 shows that this effect disappears when the discourse context is removed.These findings demonstrate that during the course of incremental comprehension, comprehenders activate general knowledge about the described event, even at points at which this knowledge would constitute an anomalous continuation of the linguistic stream. Generalized event knowledge activationcontributes to mental representations of described events, is immediately available to influence language processing, and likely drives linguistic expectancy generation. PMID:22711976

  9. Pedagogical Content Knowledge of Experts and Novices--What Knowledge Do They Activate When Analyzing Science Lessons?

    ERIC Educational Resources Information Center

    Krepf, Matthias; Plöger, Wilfried; Scholl, Daniel; Seifert, Andreas

    2018-01-01

    In the current debate on pedagogical content knowledge (PCK), the term is used to refer to the context-specific knowledge that teachers activate when reflecting on practice. Against the background of this debate, we conducted an empirical study and sought to answer the question of which knowledge experts and novices activated in assessing a…

  10. The effects of activating prior topic and metacognitive knowledge on text comprehension scores.

    PubMed

    Kostons, Danny; van der Werf, Greetje

    2015-09-01

    Research on prior knowledge activation has consistently shown that activating learners' prior knowledge has beneficial effects on learning. If learners activate their prior knowledge, this activated knowledge serves as a framework for establishing relationships between the knowledge they already possess and new information provided to them. Thus far, prior knowledge activation has dealt primarily with topic knowledge in specific domains. Students, however, likely also possess at least some metacognitive knowledge useful in those domains, which, when activated, should aid in the deployment of helpful strategies during reading. In this study, we investigated the effects of both prior topic knowledge activation (PTKA) and prior metacognitive knowledge activation (PMKA) on text comprehension scores. Eighty-eight students in primary education were randomly distributed amongst the conditions of the 2 × 2 (PTKA yes/no × PMKA yes/no) designed experiment. Results show that activating prior metacognitive knowledge had a beneficial effect on text comprehension, whereas activating prior topic knowledge, after correcting for the amount of prior knowledge, did not. Most studies deal with explicit instruction of metacognitive knowledge, but our results show that this may not be necessary, specifically in the case of students who already have some metacognitive knowledge. However, existing metacognitive knowledge needs to be activated in order for students to make better use of this knowledge. © 2015 The British Psychological Society.

  11. Knowledge, attitude and practice towards eating and physical activity among primary school children in Brunei: a cross-sectional study.

    PubMed

    Murang, Zaidah Rizidah; Tuah, Naa; Naing, Lin

    2017-11-30

    Background Childhood obesity has become a global public health crisis. Many studies have been conducted to explore the knowledge, attitude and practices towards eating and physical activity amongst parents and healthcare workers. However, very little is known amongst children. It is imperative to understand these factors as they have been associated with obesity among children. Objective This study aimed to assess the knowledge, attitude and practices of Bruneian children towards eating and physical activity, in order to identify the factors that influence the development of obesity. Methods The study involved 353 children from four primary schools in Brunei. The data collection tool used was modified validated questionnaires with sections on demographic characteristic, knowledge about obesity, eating habits and physical activity. Results The majority of children (>60%) had good knowledge of obesity and intake of healthy food, but, 84.2% lacked knowledge on the required daily servings of fruits and vegetables. 68.8% purchased food and beverages from their school canteen. 93.8% were aware about the health benefits of physical activity and 70.2% spent only 1-2 h of screen time per day, however, 46.9% did not meet the recommended amount of physical activity although they reported to have performed enough. This suggested that a comprehensive education on food intake requirements and physical activity are necessary in order to better educate children. Conclusion Health educators and public health professionals may find our findings useful in order to plan and develop tailored interventions for children, as well as better promotion of a healthy lifestyle to children and their families.

  12. 14 CFR 65.115 - Senior parachute rigger certificate: Experience, knowledge, and skill requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Senior parachute rigger certificate: Experience, knowledge, and skill requirements. 65.115 Section 65.115 Aeronautics and Space FEDERAL AVIATION... CREWMEMBERS Parachute Riggers § 65.115 Senior parachute rigger certificate: Experience, knowledge, and skill...

  13. 14 CFR 65.119 - Master parachute rigger certificate: Experience, knowledge, and skill requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Master parachute rigger certificate: Experience, knowledge, and skill requirements. 65.119 Section 65.119 Aeronautics and Space FEDERAL AVIATION... CREWMEMBERS Parachute Riggers § 65.119 Master parachute rigger certificate: Experience, knowledge, and skill...

  14. 14 CFR 65.119 - Master parachute rigger certificate: Experience, knowledge, and skill requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Master parachute rigger certificate: Experience, knowledge, and skill requirements. 65.119 Section 65.119 Aeronautics and Space FEDERAL AVIATION... CREWMEMBERS Parachute Riggers § 65.119 Master parachute rigger certificate: Experience, knowledge, and skill...

  15. 14 CFR 65.115 - Senior parachute rigger certificate: Experience, knowledge, and skill requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Senior parachute rigger certificate: Experience, knowledge, and skill requirements. 65.115 Section 65.115 Aeronautics and Space FEDERAL AVIATION... CREWMEMBERS Parachute Riggers § 65.115 Senior parachute rigger certificate: Experience, knowledge, and skill...

  16. Comparing Primary Student Teachers' Attitudes, Subject Knowledge and Pedagogical Content Knowledge Needs in a Physics Activity

    ERIC Educational Resources Information Center

    Johnston, Jane; Ahtee, Maija

    2006-01-01

    This research explores and compares primary student teachers' attitudes, subject knowledge and pedagogical content knowledge (PCK) in physics in two institutions in England and Finland, using a practical physics activity and questionnaire. Teaching of physics activities was rated unpopular both in Finland and England, although English students…

  17. Competencies required for nursing telehealth activities: A Delphi-study.

    PubMed

    van Houwelingen, Cornelis T M; Moerman, Anna H; Ettema, Roelof G A; Kort, Helianthe S M; Ten Cate, Olle

    2016-04-01

    Telehealth is viewed as a major strategy to address the increasing demand for care and a shrinking care professional population. However, most nurses are not trained or are insufficiently trained to use these technologies effectively. Therefore, the potential of telehealth fails to reach full utilization. A better understanding of nursing telehealth entrustable professional activities (NT-EPAs) and the required competencies can contribute to the development of nursing telehealth education. In a four-round Delphi-study, a panel of experts discussed which NT-EPAs are relevant for nurses and which competencies nurses need to possess to execute these activities effectively. The 51 experts, including nurses, nursing faculty, clients and technicians all familiar with telehealth, were asked to select items from a list of 52 competencies based on the literature and on a previous study. Additionally, the panelists could add competencies based on their experience in practice. The threshold used for consensus was set at 80%. Consensus was achieved on the importance of fourteen NT-EPAs, requiring one or more of the following core competencies; coaching skills, the ability to combine clinical experience with telehealth, communication skills, clinical knowledge, ethical awareness, and a supportive attitude. Each NT-EPA requires a specific set of competencies (at least ten). In total, 52 competencies were identified as essential in telehealth. Many competencies for telehealth, including clinical knowledge and communication skills, are not novel competencies. They are fundamental to nursing care as a whole and therefore are also indispensable for telehealth. Additionally, the fourteen NT-EPAs appeared to require additional subject specific competencies, such as the ability to put patients at ease when they feel insecure about using technology. The NT-EPAs and related competencies presented in this study can be used by nursing schools that are considering including or expanding

  18. Noticing relevant problem features: activating prior knowledge affects problem solving by guiding encoding

    PubMed Central

    Crooks, Noelle M.; Alibali, Martha W.

    2013-01-01

    This study investigated whether activating elements of prior knowledge can influence how problem solvers encode and solve simple mathematical equivalence problems (e.g., 3 + 4 + 5 = 3 + __). Past work has shown that such problems are difficult for elementary school students (McNeil and Alibali, 2000). One possible reason is that children's experiences in math classes may encourage them to think about equations in ways that are ultimately detrimental. Specifically, children learn a set of patterns that are potentially problematic (McNeil and Alibali, 2005a): the perceptual pattern that all equations follow an “operations = answer” format, the conceptual pattern that the equal sign means “calculate the total”, and the procedural pattern that the correct way to solve an equation is to perform all of the given operations on all of the given numbers. Upon viewing an equivalence problem, knowledge of these patterns may be reactivated, leading to incorrect problem solving. We hypothesized that these patterns may negatively affect problem solving by influencing what people encode about a problem. To test this hypothesis in children would require strengthening their misconceptions, and this could be detrimental to their mathematical development. Therefore, we tested this hypothesis in undergraduate participants. Participants completed either control tasks or tasks that activated their knowledge of the three patterns, and were then asked to reconstruct and solve a set of equivalence problems. Participants in the knowledge activation condition encoded the problems less well than control participants. They also made more errors in solving the problems, and their errors resembled the errors children make when solving equivalence problems. Moreover, encoding performance mediated the effect of knowledge activation on equivalence problem solving. Thus, one way in which experience may affect equivalence problem solving is by influencing what students encode about the

  19. Finnish Mentor Mathematics Teachers' Views of the Teacher Knowledge Required for Teaching Mathematics

    ERIC Educational Resources Information Center

    Asikainen, Mervi A.; Pehkonen, Erkki; Hirvonen, Pekka E.

    2013-01-01

    Seven Finnish mentor mathematics teachers were interviewed about their views regarding the teacher knowledge required for teaching mathematics. The results of the interviews revealed not only the teachers' spontaneous views of the knowledge base needed for effective mathematics teaching but also their views of the particular types of teacher…

  20. 14 CFR 65.119 - Master parachute rigger certificate: Experience, knowledge, and skill requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Master parachute rigger certificate... CREWMEMBERS Parachute Riggers § 65.119 Master parachute rigger certificate: Experience, knowledge, and skill requirements. An applicant for a master parachute rigger certificate must meet the following requirements: (a...

  1. 14 CFR 65.119 - Master parachute rigger certificate: Experience, knowledge, and skill requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Master parachute rigger certificate... CREWMEMBERS Parachute Riggers § 65.119 Master parachute rigger certificate: Experience, knowledge, and skill requirements. An applicant for a master parachute rigger certificate must meet the following requirements: (a...

  2. 14 CFR 65.119 - Master parachute rigger certificate: Experience, knowledge, and skill requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Master parachute rigger certificate... CREWMEMBERS Parachute Riggers § 65.119 Master parachute rigger certificate: Experience, knowledge, and skill requirements. An applicant for a master parachute rigger certificate must meet the following requirements: (a...

  3. IT Knowledge Requirements Identification in Organizational Networks: Cooperation Between Industrial Organizations and Universities

    NASA Astrophysics Data System (ADS)

    Rudzajs, Peteris; Kirikova, Marite

    ICT professionals face rapid technology development, changes in design paradigms, methodologies, approaches, and cooperation patterns. These changes impact relationships between universities that teach ICT disciplines and industrial organizations that develop and use ICT-based products. The required knowledge and skills of university graduates depend mainly on the current industrial situation; therefore the university graduates have to meet industry requirements which are stated at the time point of their graduation, not at the start of their studies. Continuous cooperation between universities and industrial organizations is needed to identify a time and situation-dependent set of knowledge requirements, which lead to situation aware, industry acknowledged, balanced and productive ICT study programs. This chapter proposes information systems solutions supporting cooperation between the university and the industrial organizations with respect to curriculum development in ICT area.

  4. Information Sharing and Knowledge Sharing as Communicative Activities

    ERIC Educational Resources Information Center

    Savolainen, Reijo

    2017-01-01

    Introduction: This paper elaborates the picture of information sharing and knowledge sharing as forms of communicative activity. Method: A conceptual analysis was made to find out how researchers have approached information sharing and knowledge sharing from the perspectives of transmission and ritual. The findings are based on the analysis of one…

  5. [Managerial knowledge required of the nurse in the family health program].

    PubMed

    Benito, Gladys Amélia Vélez; Becker, Luciana Corrêa; Duarte, Jefferson; Leite, Daniela Stuarte

    2005-01-01

    This article is a part of a study entitled "Managerial skills required of the nurse in the Family Health Program" which sought to identify the managerial knowledge required of nurses, to run the nursing services in the Family Health Units in a city on the coast of Santa Catarina. Taking the perspective of professionals working in these units, the study used the descriptive-exploratory method, with a quantitative approach and a semi-structured questionnaire. The study sample consisted of 72 participants, who attributed a score of between 1 and 5 for each item on the questionnaire. The results indicated an emphasis on the mastery of a good knowledge of SUS (the national Brazilian healthcare system) policies, which would lead to the development of skills by the nurses, enabling them to achieve a good performance and consequently, ensuring quality care and the concrete resolution of multiple problems, guaranteeing satisfaction for the community, a decrease in levels of epidemiology and a better quality of life for the population.

  6. Management Knowledge and Skills Required in the Health Care System of the Federation Bosnia and Herzegovina

    PubMed Central

    Slipicevic, Osman; Masic, Izet

    2012-01-01

    Extremely complex health care organizations, by their structure and organization, operate in a constantly changing business environment, and such situation implies and requires complex and demanding health management. Therefore, in order to manage health organizations in a competent manner, health managers must possess various managerial skills and be familiar with problems in health care. Research, identification, analysis, and assessment of health management education and training needs are basic preconditions for the development and implementation of adequate programs to meet those needs. Along with other specific activities, this research helped to determine the nature, profile, and level of top-priority needs for education. The need for knowledge of certain areas in health management, as well as the need for mastering concrete managerial competencies has been recognized as top-priorities requiring additional improvement and upgrading. PMID:23922519

  7. Knowledge Work, Working Time, and Use of Time among Finnish Dual-Earner Families: Does Knowledge Work Require the Marginalization of Private Life?

    ERIC Educational Resources Information Center

    Natti, Jouko; Anttila, Timo; Tammelin, Mia

    2012-01-01

    The industrial working-time regime is dissolving--not dramatically, but rather as a trend. A new trend is that those in dynamic sectors and in a good labor market position work long hours: Demanding knowledge work appears to require the marginalization of private life. This study investigates the family situation of knowledge workers, the…

  8. Programming Not Required: Skills and Knowledge for the Digital Library Environment

    ERIC Educational Resources Information Center

    Howard, Katherine

    2010-01-01

    Education for Library and Information professionals in managing the digital environment has been a key topic for discussion within the LIS environment for some time. However, before designing and implementing a program for digital library education, it is prudent to ensure that the skills and knowledge required to work in this environment are…

  9. Teacher Knowledge for Active-Learning Instruction: Expert-Novice Comparison Reveals Differences.

    PubMed

    Auerbach, A J; Higgins, M; Brickman, P; Andrews, T C

    2018-01-01

    Active-learning strategies can improve science, technology, engineering, and mathematics (STEM) undergraduates' abilities to learn fundamental concepts and skills. However, the results instructors achieve vary substantially. One explanation for this is that instructors commonly implement active learning differently than intended. An important factor affecting how instructors implement active learning is knowledge of teaching and learning. We aimed to discover knowledge that is important to effective active learning in large undergraduate courses. We developed a lesson-analysis instrument to elicit teacher knowledge, drawing on the theoretical construct of teacher noticing. We compared the knowledge used by expert ( n = 14) and novice ( n = 29) active-learning instructors as they analyzed lessons. Experts and novices differed in what they noticed, with experts more commonly considering how instructors hold students accountable, topic-specific student difficulties, whether the instructor elicited and responded to student thinking, and opportunities students had to generate their own ideas and work. Experts were also better able to support their lesson analyses with reasoning. This work provides foundational knowledge for the future design of preparation and support for instructors adopting active learning. Improving teacher knowledge will improve the implementation of active learning, which will be necessary to widely realize the potential benefits of active learning in undergraduate STEM. © 2018 A. J. Auerbach et al. CBE—Life Sciences Education © 2018 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  10. Engineering knowledge requirements for sand and dust on Mars

    NASA Technical Reports Server (NTRS)

    Kaplan, D. I.

    1991-01-01

    The successful landing of human beings on Mars and the establishment of a permanent outpost there will require an understanding of the Martian environment by the engineers. A key feature of the Martian environment is the nearly ubiquitous presence of sand and dust. The process which the engineering community will undertake to determine the sensitivities of their designs to the current level of knowledge about Mars sand and dust is emphasized. The interaction of the engineering community with the space exploration initiative (SEI) mission planners and management is described.

  11. Awareness and knowledge of the youth 2008 Physical Activity Guidelines for Americans.

    PubMed

    DeBastiani, Summer Dawn; Carroll, Dianna D; Cunningham, Melissa; Lee, Sarah; Fulton, Janet

    2014-03-01

    To measure parental awareness of government physical activity guidelines and knowledge of the amount of physical activity recommended for youth (ie, 60 minutes per day, 7 days per week) as specified in the 2008 Physical Activity Guidelines for Americans. A cross-sectional national sample of adults responded to physical activity guideline questions added to the HealthStyles survey in 2009 (n = 1552). The prevalence of parents aware of government physical activity guidelines and knowledgeable of the youth physical activity guideline, specifically, was estimated overall and by parental demographic characteristics (sex, education, income level, race/ethnicity, age group, marital status) and body mass index. In 2009, 34.8% of parents reported being aware of physical activity guidelines, and 9.7% were knowledgeable of the amount of physical activity recommended for youth. Many parents lack awareness and knowledge of the youth physical activity guidelines. The low prevalence estimates suggest the 2008 Physical Activity Guidelines for Americans has not been effectively disseminated. These results may also indicate a need for effective communication strategies to educate and inform parents, an important influencer of children's health behaviors.

  12. Study Results on Knowledge Requirements for Entry-Level Airport Operations and Management Personnel

    NASA Technical Reports Server (NTRS)

    Quilty, Stephen M.

    2005-01-01

    This paper identifies important topical knowledge areas required of individuals employed in airport operations and management positions. A total of 116 airport managers and airfield operations personnel responded to a survey that sought to identify the importance of various subject matter for entry level airport operations personnel. The results from this study add to the body of research on aviation management curriculum development and can be used to better develop university curriculum and supplemental training focused on airport management and operations. Recommendations are made for specialized airport courses within aviation management programs. Further, this study identifies for job seekers or individuals employed in entry level positions those knowledge requirements deemed important by airport managers and operations personnel at different sized airports.

  13. Health and Physical Activity Content Knowledge of Pima Children

    ERIC Educational Resources Information Center

    Brusseau, Timothy; Kulinna, Pamela H.; Cothran, Donetta J.

    2011-01-01

    This study grounded in constructivist theory and the public health literature investigated Native American children's knowledge related to physical activity and healthy behavior concepts. Learning tends to be more meaningful and relevant when teachers take into consideration the students' knowledge and experiences. Therefore it is important to…

  14. Enhancement of knowledge construction activities utilizing 21st century learning design rubric

    NASA Astrophysics Data System (ADS)

    Pedoche, Margarette Anne U.; Taladua, Janica Mae M.; Panal, Geicky Pearl C.; Magsayo, Joy R.; Guarin, Rica Mae B.; Myrna, H. Lahoylahoy

    2018-01-01

    The main objective of the study was to enhance knowledge construction activities on its design particularly the objectives, support materials, student activities and assessment tools. Activities from the 2nd Quarter of Science Learners Material were the basis in the adaptation of activities. The adapted activities were evaluated by the In-service Science teachers and undergone modification by the researchers based on the teacher's comments and suggestions. It was then evaluated, revised, and validated, tried-out using the 21st CLD Rubric. Subjects of the study were 110 students from Grade 7-B, Grade 7-D, Grade 7-F in Geronima Cabrera National High School, Kolambugan, Lanao del Norte during the academic year 2016-2017, the study to determine their learning capabilities investigated by the use of Knowledge Construction Activities in the 21st Century Classroom, to investigate how the lessons were understood and appreciated by students, to stimulate interpretation, analysis, synthesizing, or evaluating ideas and develop critical thinking. Both quantitative and qualitative data were obtained from the students' scores in three activities. Results showed that there was a significant difference between the pretest and posttest scores of students. Mean scores between the pretest and posttest showed a mean difference of 3.35, thus the null hypothesis was rejected. It could be concluded with sufficient evidence to show that the students had basically low prior knowledge about the topic ecosystem. A significant difference was seen in the pretest and posttest, scores of the activities and Ecosystem model results after the implementation phase that a knowledge construction type of activity was better than the traditional one for it promoted meaningful learning and active engagement of students. Based on the results, it was clear that the use of knowledge construction activities had an effect on student's achievement in comparison to traditional teaching method. Thus, it was

  15. Sexual knowledge, attitudes and activity of older people in Taipei, Taiwan.

    PubMed

    Wang, Tze-Fang; Lu, Chwen-Hwa; Chen, I-Ju; Yu, Shu

    2008-02-01

    We examined sexual activity and predictive factors among older people in Taipei, Taiwan. We aimed to characterize the older population engaged in sexual activity and determine influencing factors, exploring aspects of sexuality that may influence elders' health and quality of life (QOL). Studies of sexual attitudes and behaviour have found that sexual difficulties are common among mature adults worldwide, influenced in men and women by physical health, ageing, psychosocial and cultural factors. We conducted a community-based retrospective study involving a random sample of 412 men and 204 women over age 65. A questionnaire on demographics and social situations was administered, along with a Sexuality Knowledge and Attitudes Scale; 34 questions evaluated sexual knowledge and 18 evaluated sexual attitudes. Two-hundred and twenty participants were sexually active (35.7%), 185 mainly with spouses (84.1%); frequency was 21.4 (SD 16.9) times per year (range: 1-120). Multiple logistic regressions identified five significant predictors of sexual activity: gender, age, being with spouse, sexual knowledge and sexual attitudes. Sexual activity was significantly associated with higher education levels, lower stress and more self-reported daily activities. Our results agreed with Western studies linking sexual activity with better health and higher QOL in older adults. Older peoples' stress and daily activity levels are recognized quality-of-life measures; lower stress and more daily activities among sexually active older people suggests a connection between sexual activity and higher QOL. Increasing knowledge and improving attitudes about sexuality may help older people build healthier relationships and enhance health and QOL. Relevance to clinical practice. If healthcare professionals possess greater understanding of older peoples' sexuality, healthcare systems may find ways to increase sexual knowledge and foster healthier attitudes and relationships to improve older peoples

  16. Translating three states of knowledge--discovery, invention, and innovation

    PubMed Central

    2010-01-01

    Background Knowledge Translation (KT) has historically focused on the proper use of knowledge in healthcare delivery. A knowledge base has been created through empirical research and resides in scholarly literature. Some knowledge is amenable to direct application by stakeholders who are engaged during or after the research process, as shown by the Knowledge to Action (KTA) model. Other knowledge requires multiple transformations before achieving utility for end users. For example, conceptual knowledge generated through science or engineering may become embodied as a technology-based invention through development methods. The invention may then be integrated within an innovative device or service through production methods. To what extent is KT relevant to these transformations? How might the KTA model accommodate these additional development and production activities while preserving the KT concepts? Discussion Stakeholders adopt and use knowledge that has perceived utility, such as a solution to a problem. Achieving a technology-based solution involves three methods that generate knowledge in three states, analogous to the three classic states of matter. Research activity generates discoveries that are intangible and highly malleable like a gas; development activity transforms discoveries into inventions that are moderately tangible yet still malleable like a liquid; and production activity transforms inventions into innovations that are tangible and immutable like a solid. The paper demonstrates how the KTA model can accommodate all three types of activity and address all three states of knowledge. Linking the three activities in one model also illustrates the importance of engaging the relevant stakeholders prior to initiating any knowledge-related activities. Summary Science and engineering focused on technology-based devices or services change the state of knowledge through three successive activities. Achieving knowledge implementation requires methods that

  17. Motor skill depends on knowledge of facts.

    PubMed

    Stanley, Jason; Krakauer, John W

    2013-01-01

    Those in 20th century philosophy, psychology, and neuroscience who have discussed the nature of skilled action have, for the most part, accepted the view that being skilled at an activity is independent of knowing facts about that activity, i.e., that skill is independent of knowledge of facts. In this paper we question this view of motor skill. We begin by situating the notion of skill in historical and philosophical context. We use the discussion to explain and motivate the view that motor skill depends upon knowledge of facts. This conclusion seemingly contradicts well-known results in cognitive science. It is natural, on the face of it, to take the case of H.M., the seminal case in cognitive neuroscience that led to the discovery of different memory systems, as providing powerful evidence for the independence of knowledge and skill acquisition. After all, H.M. seems to show that motor learning is retained even when previous knowledge about the activity has been lost. Improvements in skill generally require increased precision of selected actions, which we call motor acuity. Motor acuity may indeed not require propositional knowledge and has direct parallels with perceptual acuity. We argue, however, that reflection on the specifics of H.M.'s case, as well as other research on the nature of skill, indicates that learning to become skilled at a motor task, for example tennis, depends also on knowledge-based selection of the right actions. Thus skilled activity requires both acuity and knowledge, with both increasing with practice. The moral of our discussion ranges beyond debates about motor skill; we argue that it undermines any attempt to draw a distinction between practical and theoretical activities. While we will reject the independence of skill and knowledge, our discussion leaves open several different possible relations between knowledge and skill. Deciding between them is a task to be resolved by future research.

  18. Motor skill depends on knowledge of facts

    PubMed Central

    Stanley, Jason; Krakauer, John W.

    2013-01-01

    Those in 20th century philosophy, psychology, and neuroscience who have discussed the nature of skilled action have, for the most part, accepted the view that being skilled at an activity is independent of knowing facts about that activity, i.e., that skill is independent of knowledge of facts. In this paper we question this view of motor skill. We begin by situating the notion of skill in historical and philosophical context. We use the discussion to explain and motivate the view that motor skill depends upon knowledge of facts. This conclusion seemingly contradicts well-known results in cognitive science. It is natural, on the face of it, to take the case of H.M., the seminal case in cognitive neuroscience that led to the discovery of different memory systems, as providing powerful evidence for the independence of knowledge and skill acquisition. After all, H.M. seems to show that motor learning is retained even when previous knowledge about the activity has been lost. Improvements in skill generally require increased precision of selected actions, which we call motor acuity. Motor acuity may indeed not require propositional knowledge and has direct parallels with perceptual acuity. We argue, however, that reflection on the specifics of H.M.'s case, as well as other research on the nature of skill, indicates that learning to become skilled at a motor task, for example tennis, depends also on knowledge-based selection of the right actions. Thus skilled activity requires both acuity and knowledge, with both increasing with practice. The moral of our discussion ranges beyond debates about motor skill; we argue that it undermines any attempt to draw a distinction between practical and theoretical activities. While we will reject the independence of skill and knowledge, our discussion leaves open several different possible relations between knowledge and skill. Deciding between them is a task to be resolved by future research. PMID:24009571

  19. Correlates and geographic patterns of knowledge that physical activity decreases cancer risk.

    PubMed

    Ramírez, A Susana; Finney Rutten, Lila J; Vanderpool, Robin C; Moser, Richard P; Hesse, Bradford W

    2013-04-01

    While many lifestyle-related cancer risk factors including tobacco use, poor diet, and sun exposure are well recognized by the general public, the role of physical activity in decreasing cancer risk is less recognized. Studies have demonstrated gender-, race/ethnicity-, and age-based disparities in cancer risk factor knowledge; however, beliefs and geographic factors that may be related to knowledge are under-examined. In this study, we analyzed data from the 2008 Health Information National Trends Survey to determine correlates of knowledge of the relationship between physical activity and reduced cancer risk in the adult US population. We generated geographic information system maps to examine the geographic distribution of this knowledge. Results revealed that there is confusion among US adults about the relationship between physical activity and cancer risk: Respondents who believed that cancer is not preventable had significantly lower odds of knowing that physical activity reduces cancer risk (p < .001) whereas respondents who believed that cancer is caused by one's behavior had almost two times the odds of knowing that physical activity reduces cancer risk (p < .001). Those who were aware of current physical activity guidelines were also significantly more likely to know that physical activity reduces cancer risk (p < .01). Observed geographic variability in knowledge was consistent with geographic trends in obesity and physical inactivity. Correlates of cancer risk factor knowledge point to opportunities for targeted interventions.

  20. Integration of Humanitarian Knowledge in Art and Design Activity

    ERIC Educational Resources Information Center

    Kamzina, Nadezhda Enovna; Mazina, Julia Ilyinichna; Turganbayeva, Shakhizada Sainbekovna

    2016-01-01

    The process of integration of humanitarian knowledge is being examined in the article and the development of the project activities and a special outlook on the examples of famous artists, designers and architects are investigated. The forms of creative thinking are systematized and the factors modifying the borders of design knowledge are formed…

  1. Knowledge of Senior Center Activities among the Elderly.

    ERIC Educational Resources Information Center

    Krout, John A.

    In the past few decades, senior centers have developed at an exponential rate. To investigate elderly citizens' knowledge of senior center activities and services, 250 white older adults (125 center users and 125 nonusers) from a small urban community were personally interviewed about the services and activities provided by their local senior…

  2. Nutrition knowledge of active-duty Navy personnel.

    PubMed

    Trent, L K

    1992-06-01

    As evidence continues to mount implicating diet in the etiology of disease, the US Navy is developing nutrition education programs designed to reflect the consolidated dietary recommendations of national expert agencies. The purpose of this study was to provide a baseline assessment of the level of nutrition knowledge among Navy personnel. Forty true/false questions were developed to test nutrition knowledge as conveyed by the Navy's instructional manual for nutrition educators. The questionnaire was mailed to a representative sample of all active-duty Navy personnel. Usable questionnaires were received from 2,938 participants (72.7% response rate). Mean number of correct items was 26.1 (65%). Nutrition knowledge was higher among older respondents, more highly educated personnel, whites, officers, women, and overweight individuals. Knowledge was weakest in the areas of calories/food intake and carbohydrates and strongest on vitamins/minerals and fiber. Program managers were recommended to intensify efforts to reach low-scoring subgroups, place more emphasis on the role of complex carbohydrates, disseminate guidelines for using nutrition labels on products, and develop point-of-choice nutrition education interventions for military dining facilities.

  3. Active and passive spatial learning in human navigation: acquisition of graph knowledge.

    PubMed

    Chrastil, Elizabeth R; Warren, William H

    2015-07-01

    It is known that active exploration of a new environment leads to better spatial learning than does passive visual exposure. We ask whether specific components of active learning differentially contribute to particular forms of spatial knowledge-the exploration-specific learning hypothesis. Previously, we found that idiothetic information during walking is the primary active contributor to metric survey knowledge (Chrastil & Warren, 2013). In this study, we test the contributions of 3 components to topological graph and route knowledge: visual information, idiothetic information, and cognitive decision making. Four groups of participants learned the locations of 8 objects in a virtual hedge maze by (a) walking or (b) watching a video, crossed with (1) either making decisions about their path or (2) being guided through the maze. Route and graph knowledge were assessed by walking in the maze corridors from a starting object to the remembered location of a test object, with frequent detours. Decision making during exploration significantly contributed to subsequent route finding in the walking condition, whereas idiothetic information did not. Participants took novel routes and the metrically shortest routes on the majority of both direct and barrier trials, indicating that labeled graph knowledge-not merely route knowledge-was acquired. We conclude that, consistent with the exploration-specific learning hypothesis, decision making is the primary component of active learning for the acquisition of topological graph knowledge, whereas idiothetic information is the primary component for metric survey knowledge. (c) 2015 APA, all rights reserved.

  4. Knowledge-Integration Processes and Learning Outcomes Associated with a Self-Diagnosis Activity: The Case of 5th-Graders Studying Simple Fractions

    ERIC Educational Resources Information Center

    Safadi, Rafi'

    2018-01-01

    I examined how well a self-diagnosis activity engages students in knowledge-integration processes, and its impact on students' mathematical achievements. The self-diagnosis activity requires students to self-diagnose their solutions to problems that they have solved on their own--namely, to identify where they went wrong and to explain the nature…

  5. Decision Support System Requirements Definition for Human Extravehicular Activity Based on Cognitive Work Analysis

    PubMed Central

    Miller, Matthew James; McGuire, Kerry M.; Feigh, Karen M.

    2016-01-01

    The design and adoption of decision support systems within complex work domains is a challenge for cognitive systems engineering (CSE) practitioners, particularly at the onset of project development. This article presents an example of applying CSE techniques to derive design requirements compatible with traditional systems engineering to guide decision support system development. Specifically, it demonstrates the requirements derivation process based on cognitive work analysis for a subset of human spaceflight operations known as extravehicular activity. The results are presented in two phases. First, a work domain analysis revealed a comprehensive set of work functions and constraints that exist in the extravehicular activity work domain. Second, a control task analysis was performed on a subset of the work functions identified by the work domain analysis to articulate the translation of subject matter states of knowledge to high-level decision support system requirements. This work emphasizes an incremental requirements specification process as a critical component of CSE analyses to better situate CSE perspectives within the early phases of traditional systems engineering design. PMID:28491008

  6. Decision Support System Requirements Definition for Human Extravehicular Activity Based on Cognitive Work Analysis.

    PubMed

    Miller, Matthew James; McGuire, Kerry M; Feigh, Karen M

    2017-06-01

    The design and adoption of decision support systems within complex work domains is a challenge for cognitive systems engineering (CSE) practitioners, particularly at the onset of project development. This article presents an example of applying CSE techniques to derive design requirements compatible with traditional systems engineering to guide decision support system development. Specifically, it demonstrates the requirements derivation process based on cognitive work analysis for a subset of human spaceflight operations known as extravehicular activity . The results are presented in two phases. First, a work domain analysis revealed a comprehensive set of work functions and constraints that exist in the extravehicular activity work domain. Second, a control task analysis was performed on a subset of the work functions identified by the work domain analysis to articulate the translation of subject matter states of knowledge to high-level decision support system requirements. This work emphasizes an incremental requirements specification process as a critical component of CSE analyses to better situate CSE perspectives within the early phases of traditional systems engineering design.

  7. Proposed Conceptual Requirements for the CTBT Knowledge Base,

    DTIC Science & Technology

    1995-08-14

    knowledge available to automated processing routines and human analysts are significant, and solving these problems is an essential step in ensuring...knowledge storage in a CTBT system. In addition to providing regional knowledge to automated processing routines, the knowledge base will also address

  8. Activation of Background Knowledge for Inference Making: Effects on Reading Comprehension

    ERIC Educational Resources Information Center

    Elbro, Carsten; Buch-Iversen, Ida

    2013-01-01

    Failure to "activate" relevant, existing background knowledge may be a cause of poor reading comprehension. This failure may cause particular problems with inferences that depend heavily on prior knowledge. Conversely, teaching how to use background knowledge in the context of gap-filling inferences could improve reading comprehension in…

  9. The Body of Knowledge & Content Framework. Identifying the Important Knowledge Required for Productive Performance of a Plastics Machine Operator. Blow Molding, Extrusion, Injection Molding, Thermoforming.

    ERIC Educational Resources Information Center

    Society of the Plastics Industry, Inc., Washington, DC.

    Designed to guide training and curriculum development to prepare machine operators for the national certification exam, this publication identifies the important knowledge required for productive performance by a plastics machine operator. Introductory material discusses the rationale for a national standard, uses of the Body of Knowledge,…

  10. A simple screening method for determining knowledge of the appropriate levels of activity and risk behaviour in young people with congenital cardiac conditions.

    PubMed

    Kendall, Lynne; Parsons, Jonathan M; Sloper, Patricia; Lewin, Robert J P

    2007-04-01

    To assess a novel method for assessing risk and providing advice about activity to children and young people with congenital cardiac disease and their parents. Questionnaire survey in outpatient clinics at a tertiary centre dealing with congenital cardiac disease, and 6 peripheral clinics. Children or their parents completed a brief questionnaire. If this indicated a desire for help, or a serious mismatch between advised and real level of activity, they were telephoned by a physiotherapist. MAIN MEASURES OF OUTCOME: Knowledge about appropriate levels of activity, and identification of the number exercising at an unsafe level, the number seeking help, and the type of help required. 253/258 (98.0%) questionnaires were returned, with 119/253 (47.0%) showing incorrect responses in their belief about their advised level of exercise; 17/253 (6.7%) had potentially dangerous overestimation of exercise. Asked if they wanted advice 93/253 (36.8%) said "yes", 43/253 (17.0%) "maybe", and 117/253 (46.2%) "no". Of those contacted by phone to give advice, 72.7% (56/77) required a single contact and 14.3% (11/77) required an intervention that required more intensive contact lasting from 2 up to 12 weeks. Of the cohort, 3.9% (3/77) were taking part in activities that put them at significant risk. There is a significant lack of knowledge about appropriate levels of activity, and a desire for further advice, in children and young people with congenital cardiac disease. A few children may be at very significant risk. These needs can be identified, and clinical risk reduced, using a brief self-completed questionnaire combined with telephone follow-up from a suitably knowledgeable physiotherapist.

  11. A Knowledge-Based and Model-Driven Requirements Engineering Approach to Conceptual Satellite Design

    NASA Astrophysics Data System (ADS)

    Dos Santos, Walter A.; Leonor, Bruno B. F.; Stephany, Stephan

    Satellite systems are becoming even more complex, making technical issues a significant cost driver. The increasing complexity of these systems makes requirements engineering activities both more important and difficult. Additionally, today's competitive pressures and other market forces drive manufacturing companies to improve the efficiency with which they design and manufacture space products and systems. This imposes a heavy burden on systems-of-systems engineering skills and particularly on requirements engineering which is an important phase in a system's life cycle. When this is poorly performed, various problems may occur, such as failures, cost overruns and delays. One solution is to underpin the preliminary conceptual satellite design with computer-based information reuse and integration to deal with the interdisciplinary nature of this problem domain. This can be attained by taking a model-driven engineering approach (MDE), in which models are the main artifacts during system development. MDE is an emergent approach that tries to address system complexity by the intense use of models. This work outlines the use of SysML (Systems Modeling Language) and a novel knowledge-based software tool, named SatBudgets, to deal with these and other challenges confronted during the conceptual phase of a university satellite system, called ITASAT, currently being developed by INPE and some Brazilian universities.

  12. Knowledge of pediatricians regarding physical activity in childhood and adolescence

    PubMed Central

    Gordia, Alex Pinheiro; de Quadros, Teresa Maria Bianchini; Silva, Luciana Rodrigues; dos Santos, Gilton Marques

    2015-01-01

    Objective: To investigate the knowledge and guidance given by pediatricians regarding physical activity in childhood and adolescence. Methods: A cross-sectional study involving a convenience sample of pediatricians (n=210) who participated in a national pediatrics congress in 2013. Sociodemographic and professional data and data regarding habitual physical activity and pediatricians’ knowledge and instructions for young people regarding physical activity were collected using a questionnaire. Absolute and relative frequencies and means and standard deviations were calculated. Results: Most pediatricians were females, had graduated from medical school more than 15 years ago, and had residency in pediatrics. More than 70% of the participants reported to include physical activity guidance in their prescriptions. On the other hand, approximately two-thirds of the pediatricians incorrectly reported that children should not work out and less than 15% answered the question about physical activity barriers correctly. With respect to the two questions about physical activity to tackle obesity, incorrect answers were marked by more than 50% of the pediatricians. Most participants incorrectly reported that 30 min should be the minimum daily time of physical activity in young people. Less than 40% of the pediatricians correctly indicated the maximum time young people should spend in front of a screen. Conclusions: In general, the pediatricians reported that they recommend physical activity to their young patients, but specific knowledge of this topic was limited. Programs providing adequate information are needed. PMID:26298654

  13. Motivational activities based on previous knowledge of students

    NASA Astrophysics Data System (ADS)

    García, J. A.; Gómez-Robledo, L.; Huertas, R.; Perales, F. J.

    2014-07-01

    Academic results depend strongly on the individual circumstances of students: background, motivation and aptitude. We think that academic activities conducted to increase motivation must be tuned to the special situation of the students. Main goal of this work is analyze the students in the first year of the Degree in Optics and Optometry in the University of Granada and the suitability of an activity designed for those students. Initial data were obtained from a survey inquiring about the reasons to choose this degree, their knowledge of it, and previous academic backgrounds. Results show that: 1) the group is quite heterogeneous, since students have very different background. 2) Reasons to choose the Degree in Optics and Optometry are also very different, and in many cases were selected as a second option. 3) Knowledge and motivations about the Degree are in general quite low. Trying to increase the motivation of the students we designed an academic activity in which we show different topics studied in the Degree. Results show that students that have been involved in this activity are the most motivated and most satisfied with their election of the degree.

  14. Instructional Transaction Theory: Knowledge Relationships among Processes, Entities, and Activities.

    ERIC Educational Resources Information Center

    Merrill, M. David; And Others

    1993-01-01

    Discussion of instructional transaction theory focuses on knowledge representation in an automated instructional design expert system. A knowledge structure called PEA-Net (processes, entities, and activities) is explained; the refrigeration process is used as an example; text resources and graphic resources are described; and simulations are…

  15. Knowledge and Skill Requirements for Marketing Jobs in the 21st Century

    ERIC Educational Resources Information Center

    Schlee, Regina Pefanis; Harich, Katrin R.

    2010-01-01

    This study examines the skills and conceptual knowledge that employers require for marketing positions at different levels ranging from entry- or lower-level jobs to middle- and senior-level positions. The data for this research are based on a content analysis of 500 marketing jobs posted on Monster.com for Atlanta, Chicago, Los Angeles, New York…

  16. Describing functional requirements for knowledge sharing communities

    NASA Technical Reports Server (NTRS)

    Garrett, Sandra; Caldwell, Barrett

    2002-01-01

    Human collaboration in distributed knowledge sharing groups depends on the functionality of information and communication technologies (ICT) to support performance. Since many of these dynamic environments are constrained by time limits, knowledge must be shared efficiently by adapting the level of information detail to the specific situation. This paper focuses on the process of knowledge and context sharing with and without mediation by ICT, as well as issues to be resolved when determining appropriate ICT channels. Both technology-rich and non-technology examples are discussed.

  17. [Knowledge of pediatricians regarding physical activity in childhood and adolescence].

    PubMed

    Gordia, Alex Pinheiro; de Quadros, Teresa Maria Bianchini; Silva, Luciana Rodrigues; dos Santos, Gilton Marques

    2015-12-01

    To investigate the knowledge and guidance given by pediatricians regarding physical activity in childhood and adolescence. A cross-sectional study involving a convenience sample of pediatricians (n=210) who participated in a national pediatrics congress in 2013. Sociodemographic and professional data and data regarding habitual physical activity and pediatricians' knowledge and instructions for young people regarding physical activity were collected using a questionnaire. Absolute and relative frequencies and means and standard deviations were calculated. Most pediatricians were females, had graduated from medical school more than 15 years ago, and had residency in pediatrics. More than 70% of the participants reported to include physical activity guidance in their prescriptions. On the other hand, approximately two-thirds of the pediatricians incorrectly reported that children should not work out and less than 15% answered the question about physical activity barriers correctly. With respect to the two questions about physical activity to tackle obesity, incorrect answers were marked by more than 50% of the pediatricians. Most participants incorrectly reported that 30 minutes should be the minimum daily time of physical activity in young people. Less than 40% of the pediatricians correctly indicated the maximum time young people should spend in front of a screen. In general, the pediatricians reported that they recommend physical activity to their young patients, but specific knowledge of this topic was limited. Programs providing adequate information are needed. Copyright © 2015 Sociedade de Pediatria de São Paulo. Publicado por Elsevier Editora Ltda. All rights reserved.

  18. Improving preservice chemistry teachers' content knowledge through intervention activities

    NASA Astrophysics Data System (ADS)

    Wheeldon, Ruth

    2017-06-01

    The effect of intervention activities on the chemistry content knowledge of 92 preservice chemistry teachers (PSCT) was examined via a pre and post true/false with confidence level test focusing on ionisation energy values and the use of a common alternative conception (AC). Data were collected from three cohorts of PSCT each engaged in a one year full-time university-based teacher education programme. Comparison of pre-and post-test responses and discrimination differences between responses for each PSCT were used to identify the use of the AC and hence the efficacy of the intervention activities. Interviews with 14 of these PSCT allowed triangulation of the data. Findings suggest that the activities allow 71% of PSCT to identify this AC as non-scientific or become more confident in doing so. Interview data indicate that this rejection of this AC is sustained for 9 of the 11 PSCT whose test data indicated improvement. These data have implications for teacher education such that 2 hour intervention sessions can offer the opportunity for PSCT to develop their subject matter knowledge. As the accurate application of electrostatic concepts to electrons has wider application to bonding, these interventions offer PSCT more accurate chemical subject knowledge resources to draw on in their teaching.

  19. Knowledge-Building Activity Structures in Japanese Elementary Science Pedagogy

    ERIC Educational Resources Information Center

    Oshima, Jun; Oshima, Ritsuko; Murayama, Isao; Inagaki, Shigenori; Takenaka, Makiko; Yamamoto, Tomokazu; Yamaguchi, Etsuji; Nakayama, Hayashi

    2006-01-01

    The purpose of this study is to refine Japanese elementary science activity structures by using a CSCL approach to transform the classroom into a knowledge-building community. We report design studies on two science lessons in two consecutive years and describe the progressive refinement of the activity structures. Through comparisons of student…

  20. Sexual knowledge, attitudes and activity of men conscripted into the military

    PubMed Central

    2010-01-01

    Background Military conscripts may experience a change in their attitude towards sex at times when sexual urges are at their peak during their physical growth. This study examines the experience, understanding, knowledge and attitudes regarding sexual activity of the military conscripts. Methods Data was obtained from a cross-sectional survey of 1127 young adult military conscripts, and were evaluated in Southern Taiwan from January to July 2009, their demographic data, sexual knowledge, attitudes and activities were assessed. Results Nearly 43% of the participants had performed penetrative vaginal intercourse at least once; 34% of the participants performed heterosexual oral sex at least once; almost 7% of participants had had homosexual intercourse, and 7.5% of participants had experienced homosexual oral sex in the past year. The mean sexual knowledge score based on 30 questions was 23.2 ± 4.0. The higher the educational level of the participants, the greater sexual knowledge they had obtained. Conclusion This study found that 43% of unmarried young recruits had experienced premarital sexual activity. However, their sexual knowledge was insufficient and should be strengthened by sex education from an earlier age. College aged and adult learners also have sex education needs, especially with regard to integrating sexuality and life, being able to relate responsibly as sexual beings to others, the use of contraception, and about sexually transmitted disease. Keywords Young recruits, Sexual behavior, Sexual knowledge, Sex education PMID:20875121

  1. Engaging national organizations for knowledge translation: comparative case studies in knowledge value mapping.

    PubMed

    Lane, Joseph P; Rogers, Juan D

    2011-09-12

    should result in higher levels of knowledge awareness, interest, and use, which can then be documented. National organizations and their members, in turn, can strive to optimize their absorptive capacities regarding the state of the sciences. This combination will ensure the highest possible return on public investment in research activities. This knowledge-value mapping study concludes that national organizations are appropriate channels for communicating research findings and for meeting statutory requirements and general expectations for generating and documenting knowledge use.

  2. Effects of Biology Teachers' Professional Knowledge and Cognitive Activation on Students' Achievement

    ERIC Educational Resources Information Center

    Förtsch, Christian; Werner, Sonja; von Kotzebue, Lena; Neuhaus, Birgit J.

    2016-01-01

    This study examined the effects of teachers' biology-specific dimensions of professional knowledge--pedagogical content knowledge (PCK) and content knowledge (CK)--and cognitively activating biology instruction, as a feature of instructional quality, on students' learning. The sample comprised 39 German secondary school teachers whose lessons on…

  3. Effects of biology teachers' professional knowledge and cognitive activation on students' achievement

    NASA Astrophysics Data System (ADS)

    Förtsch, Christian; Werner, Sonja; von Kotzebue, Lena; Neuhaus, Birgit J.

    2016-11-01

    This study examined the effects of teachers' biology-specific dimensions of professional knowledge - pedagogical content knowledge (PCK) and content knowledge (CK) - and cognitively activating biology instruction, as a feature of instructional quality, on students' learning. The sample comprised 39 German secondary school teachers whose lessons on the topic neurobiology were videotaped twice. Teachers' instruction was coded with regard to cognitive activation using a rating manual. Multilevel path analysis results showed a positive significant effect of cognitive activation on students' learning and an indirect effect of teachers' PCK on students' learning mediated through cognitive activation. These findings highlight the importance of PCK in preservice biology teachers' education. Items of the rating manual may be used to provide exemplars of concrete teaching situations during university seminars for preservice teacher education or professional development initiatives for in-service teachers.

  4. Children's daily activities and knowledge acquisition: A case study among the Baka from southeastern Cameroon.

    PubMed

    Gallois, Sandrine; Duda, Romain; Hewlett, Barry; Reyes-García, Victoria

    2015-12-24

    The acquisition of local knowledge occurs through complex interactions between individual and contextual characteristics: as context changes, so it changes the acquisition of knowledge. Contemporary small-scale societies facing rapid social-ecological change provide a unique opportunity to study the relation between social-ecological changes and the process of acquisition of local knowledge. In this work, we study children's involvement in subsistence related activities (i.e., hunting and gathering) in a context of social-ecological change and discuss how such involvement might condition the acquisition of local knowledge during childhood. We interviewed 98 children from a hunter-gatherer society, the Baka, living in two different villages in southeastern Cameroon and assessed their involvement in daily activities. Using interviews, we collected self-reported data on the main activities performed during the previous 24 h. We describe the frequency of occurrence of daily activities during middle childhood and adolescence and explore the variation in occurrence according to the sex, the age group, and the village of residency of the child. We also explore variation according to the season in which the activity is conducted and to the predicted potential of the activity for the acquisition of local knowledge. Baka children and adolescents engage in subsistence-related activities (i.e., hunting and gathering) and playing more frequently than in other activities (i.e., traditional tales or schooling). Gender differences in children's subsistence activities emerge at an early age. Engagement in activities also varies with age, with adolescents spending more time in agricultural activities, modern leisure (i.e., going to bars), and socializing than younger children. When conducting similar activities, adolescents use more complex techniques than younger children. Subsistence activities, which present a high potential for transmission of local knowledge, continue to be

  5. Parental Strategies for Knowledge of Adolescents' Friends: Distinct from Monitoring?

    ERIC Educational Resources Information Center

    Bourdeau, Beth; Miller, Brenda A.; Duke, Michael R.; Ames, Genevieve M.

    2011-01-01

    Parental monitoring is defined as a set of behaviors used to gain knowledge about an adolescent's whereabouts, friends and associates, and activities. However, can knowledge of adolescents' whereabouts/activities, and friends all be attained through the same strategies? Or do they require their own strategies? This study used qualitative…

  6. The Impact of a Required Undergraduate Health and Wellness Course on Students' Awareness and Knowledge of Physical Activity and Chronic Disease

    ERIC Educational Resources Information Center

    Kuruganti, Usha

    2014-01-01

    As part of the undergraduate curriculum, the Faculty of Kinesiology at the University of New Brunswick (UNB) requires all students to take an undergraduate course in physical activity, health and wellness in their third year of study. This capstone course allows students to integrate concepts from their program regarding physical activity,…

  7. Passive vs Active Knowledge Transfer: boosting grant proposal impact

    NASA Astrophysics Data System (ADS)

    Grigorov, Ivo; Bayliss-Brown, Georgia; Murphy, David; Thøgersen, Thomas; Mariani, Patrizio

    2017-04-01

    Research funders are increasingly concerned with measurable socio-economic impact of investment in research, and on increasingly shorter timescales. Innovation, and "open innovation" are the policy priorities of the moment and optimising the flow of ideas along the lab-2-market spectrum is essential for re-use of results, fuelling open innovation, and boosting socio-economic impact or public funded research. The presentation showcases two complimentary strategies that Project Managers can employ pre- and/or post-award in order to optimise the exploitation and impact of research project: passive and active knowledge transfer. Passive Knowledge Transfer relies on maximum disclosure of research output (other than commercially exploitable research via patents and other IPR) in the interest of optimal reproducibility, independent validation and re-use by both academic and non-academic users, without necessarily targeting specific users. Tools of the trade include standard public & academic dissemination means (research articles, online media publications, newsletters, generic policy briefs). Additional transparency of the research workflow can be achieved by integrating "open science" (open notebooks, open data, open research software and open access to research publications) as well as Virtual Research Environments (VREs) in the methodology of the proposed work. Ensuring that the proposal partners are suitably trained in best practices of open science, makes proposal grant more competitive at evaluation and the resulting maximum access to research outputs does contribute to better return on investment for funders (Beagrie 2016) and economic growth objectives of public s e.g. Blue Growth (Houghton & Swan 2011, Marine Knowledge 2020 Roadmap). Active Knowledge Transfer, or the pro-active translation of research into policy or commercial context, is the more classical and better known approach (also referred to as extension services, or researchers providing advice e.g. to

  8. Prior knowledge guided active modules identification: an integrated multi-objective approach.

    PubMed

    Chen, Weiqi; Liu, Jing; He, Shan

    2017-03-14

    Active module, defined as an area in biological network that shows striking changes in molecular activity or phenotypic signatures, is important to reveal dynamic and process-specific information that is correlated with cellular or disease states. A prior information guided active module identification approach is proposed to detect modules that are both active and enriched by prior knowledge. We formulate the active module identification problem as a multi-objective optimisation problem, which consists two conflicting objective functions of maximising the coverage of known biological pathways and the activity of the active module simultaneously. Network is constructed from protein-protein interaction database. A beta-uniform-mixture model is used to estimate the distribution of p-values and generate scores for activity measurement from microarray data. A multi-objective evolutionary algorithm is used to search for Pareto optimal solutions. We also incorporate a novel constraints based on algebraic connectivity to ensure the connectedness of the identified active modules. Application of proposed algorithm on a small yeast molecular network shows that it can identify modules with high activities and with more cross-talk nodes between related functional groups. The Pareto solutions generated by the algorithm provides solutions with different trade-off between prior knowledge and novel information from data. The approach is then applied on microarray data from diclofenac-treated yeast cells to build network and identify modules to elucidate the molecular mechanisms of diclofenac toxicity and resistance. Gene ontology analysis is applied to the identified modules for biological interpretation. Integrating knowledge of functional groups into the identification of active module is an effective method and provides a flexible control of balance between pure data-driven method and prior information guidance.

  9. Verb Aspect and the Activation of Event Knowledge

    ERIC Educational Resources Information Center

    Ferretti, Todd R.; Kutas, Marta; McRae, Ken

    2007-01-01

    The authors show that verb aspect influences the activation of event knowledge with 4 novel results. First, common locations of events (e.g., arena) are primed following verbs with imperfective aspect (e.g., was skating) but not verbs with perfect aspect (e.g., had skated). Second, people generate more locative prepositional phrases as…

  10. Comparative analysis of knowledge representation and reasoning requirements across a range of life sciences textbooks.

    PubMed

    Chaudhri, Vinay K; Elenius, Daniel; Goldenkranz, Andrew; Gong, Allison; Martone, Maryann E; Webb, William; Yorke-Smith, Neil

    2014-01-01

    Using knowledge representation for biomedical projects is now commonplace. In previous work, we represented the knowledge found in a college-level biology textbook in a fashion useful for answering questions. We showed that embedding the knowledge representation and question-answering abilities in an electronic textbook helped to engage student interest and improve learning. A natural question that arises from this success, and this paper's primary focus, is whether a similar approach is applicable across a range of life science textbooks. To answer that question, we considered four different textbooks, ranging from a below-introductory college biology text to an advanced, graduate-level neuroscience textbook. For these textbooks, we investigated the following questions: (1) To what extent is knowledge shared between the different textbooks? (2) To what extent can the same upper ontology be used to represent the knowledge found in different textbooks? (3) To what extent can the questions of interest for a range of textbooks be answered by using the same reasoning mechanisms? Our existing modeling and reasoning methods apply especially well both to a textbook that is comparable in level to the text studied in our previous work (i.e., an introductory-level text) and to a textbook at a lower level, suggesting potential for a high degree of portability. Even for the overlapping knowledge found across the textbooks, the level of detail covered in each textbook was different, which requires that the representations must be customized for each textbook. We also found that for advanced textbooks, representing models and scientific reasoning processes was particularly important. With some additional work, our representation methodology would be applicable to a range of textbooks. The requirements for knowledge representation are common across textbooks, suggesting that a shared semantic infrastructure for the life sciences is feasible. Because our representation overlaps

  11. Engaging national organizations for knowledge translation: Comparative case studies in knowledge value mapping

    PubMed Central

    2011-01-01

    capacity of nonscholars. Greater absorption should result in higher levels of knowledge awareness, interest, and use, which can then be documented. National organizations and their members, in turn, can strive to optimize their absorptive capacities regarding the state of the sciences. This combination will ensure the highest possible return on public investment in research activities. This knowledge-value mapping study concludes that national organizations are appropriate channels for communicating research findings and for meeting statutory requirements and general expectations for generating and documenting knowledge use. PMID:21910866

  12. Knowledge engineering for health: a new discipline required to bridge the "ICT gap" between research and healthcare.

    PubMed

    Beck, Tim; Gollapudi, Sirisha; Brunak, Søren; Graf, Norbert; Lemke, Heinz U; Dash, Debasis; Buchan, Iain; Díaz, Carlos; Sanz, Ferran; Brookes, Anthony J

    2012-05-01

    Despite vast amount of money and research being channeled toward biomedical research, relatively little impact has been made on routine clinical practice. At the heart of this failure is the information and communication technology "chasm" that exists between research and healthcare. A new focus on "knowledge engineering for health" is needed to facilitate knowledge transmission across the research-healthcare gap. This discipline is required to engineer the bidirectional flow of data: processing research data and knowledge to identify clinically relevant advances and delivering these into healthcare use; conversely, making outcomes from the practice of medicine suitably available for use by the research community. This system will be able to self-optimize in that outcomes for patients treated by decisions that were based on the latest research knowledge will be fed back to the research world. A series of meetings, culminating in the "I-Health 2011" workshop, have brought together interdisciplinary experts to map the challenges and requirements for such a system. Here, we describe the main conclusions from these meetings. An "I4Health" interdisciplinary network of experts now exists to promote the key aims and objectives, namely "integrating and interpreting information for individualized healthcare," by developing the "knowledge engineering for health" domain. © 2012 Wiley Periodicals, Inc.

  13. Identifying knowledge activism in worker health and safety representation: A cluster analysis.

    PubMed

    Hall, Alan; Oudyk, John; King, Andrew; Naqvi, Syed; Lewchuk, Wayne

    2016-01-01

    Although worker representation in OHS has been widely recognized as contributing to health and safety improvements at work, few studies have examined the role that worker representatives play in this process. Using a large quantitative sample, this paper seeks to confirm findings from an earlier exploratory qualitative study that worker representatives can be differentiated by the knowledge intensive tactics and strategies that they use to achieve changes in their workplace. Just under 900 worker health and safety representatives in Ontario completed surveys which asked them to report on the amount of time they devoted to different types of representation activities (i.e., technical activities such as inspections and report writing vs. political activities such as mobilizing workers to build support), the kinds of conditions or hazards they tried to address through their representation (e.g., housekeeping vs. modifications in ventilation systems), and their reported success in making positive improvements. A cluster analysis was used to determine whether the worker representatives could be distinguished in terms of the relative time devoted to different activities and the clusters were then compared with reference to types of intervention efforts and outcomes. The cluster analysis identified three distinct groupings of representatives with significant differences in reported types of interventions and in their level of reported impact. Two of the clusters were consistent with the findings in the exploratory study, identified as knowledge activism for greater emphasis on knowledge based political activity and technical-legal representation for greater emphasis on formalized technical oriented procedures and legal regulations. Knowledge activists were more likely to take on challenging interventions and they reported more impact across the full range of interventions. This paper provides further support for the concepts of knowledge activism and technical

  14. Eliciting and Representing High-Level Knowledge Requirements to Discover Ecological Knowledge in Flower-Visiting Data

    PubMed Central

    2016-01-01

    Observations of individual organisms (data) can be combined with expert ecological knowledge of species, especially causal knowledge, to model and extract from flower–visiting data useful information about behavioral interactions between insect and plant organisms, such as nectar foraging and pollen transfer. We describe and evaluate a method to elicit and represent such expert causal knowledge of behavioral ecology, and discuss the potential for wider application of this method to the design of knowledge-based systems for knowledge discovery in biodiversity and ecosystem informatics. PMID:27851814

  15. Spheres of Knowledge that Require Open-mindedness and Open Data

    NASA Astrophysics Data System (ADS)

    Branch, B. D.

    2009-05-01

    The progress of social knowledge is impeded if not paralyzed at present by two fundamental factors, one impinging from knowledge without, and the other operating within the world of science itself' (Mannheim, Wirth, and Shils, p. xi). Hence, a Sphere of Knowledge (SK) defined here as a pseudo-ontology, may require a societal open-mindedness as defined by Dewey (1912). With professional open-mindedness and open data use, such social constructs may bridge and build relations towards efficient and effective societal problem solving. Open data use is defined where information has to be gathered from many sources to provided input for latter decision-making in the public interest. Here, spatial thinking may be the heart of data collection, analysis, and reporting that sustains an informatics experience among all parts of society. Here, at risk may be human survival and sustainability if policy and politics has hindered scientific or evidence-based transfer. Executive Order 12096, Coordinating Geographical Data Acquisition and Access: The National Spatial Data Infrastructure, by the federal government in 1994, may be an example of an informatics gap of knowledge where a federal mandate is not being connected to geosciences tools and community leaders that could benefit an open society. Critical in a SK is how an open society makes effective decisions if the issues it faces are new with unpredictable outcomes. Policy and politics should not impede the scientific or evidence based knowledge transfer but should be a root of democratic tools. Policy development and implementation should reflect such complexities' (Gardner, et al, 2003, p. 2). Conceptually, a SK may be too broad for any one disciplinary to address effectively as a next generation concern. The demand for deep integration of scientific data within and between disciplines is also growing, as larger and broader science questions are becoming more common. Concurrent with the growing demand for next generation

  16. Using an ACTIVE teaching format versus a standard lecture format for increasing resident interaction and knowledge achievement during noon conference: a prospective, controlled study.

    PubMed

    Sawatsky, Adam P; Berlacher, Kathryn; Granieri, Rosanne

    2014-07-01

    The traditional lecture is used by many residency programs to fulfill the mandate for regular didactic sessions, despite limited evidence to demonstrate its effectiveness. Active teaching strategies have shown promise in improving medical knowledge but have been challenging to implement within the constraints of residency training. We developed and evaluated an innovative structured format for interactive teaching within the residency noon conference. We developed an ACTIVE teaching format structured around the following steps: assemble (A) into groups, convey (C) learning objectives, teach (T) background information, inquire (I) through cases and questions, verify (V) understanding, and explain (E) answer choices and educate on the learning points. We conducted a prospective, controlled study of the ACTIVE teaching format versus the standard lecture format, comparing resident satisfaction, immediate knowledge achievement and long-term knowledge retention. We qualitatively assessed participating faculty members' perspectives on the faculty development efforts and the feasibility of teaching using the ACTIVE format. Sixty-nine internal medicine residents participated in the study. Overall, there was an improvement in perceived engagement using the ACTIVE teaching format (4.78 vs. 3.80, P < 0.01), with no increase in stress or decrement in break time. There was an improvement in initial knowledge achievement with the ACTIVE teaching format (overall absolute score increase of 11%, P = 0.04) and a trend toward improvement in long-term knowledge retention. Faculty members felt adequately prepared to use the ACTIVE teaching format, and enjoyed teaching with the ACTIVE teaching format more than the standard lecture. A structured ACTIVE teaching format improved resident engagement and initial knowledge, and required minimal resources. The ACTIVE teaching format offers an exciting alternative to the standard lecture for resident noon conference and is easy to implement.

  17. Using an ACTIVE teaching format versus a standard lecture format for increasing resident interaction and knowledge achievement during noon conference: a prospective, controlled study

    PubMed Central

    2014-01-01

    Background The traditional lecture is used by many residency programs to fulfill the mandate for regular didactic sessions, despite limited evidence to demonstrate its effectiveness. Active teaching strategies have shown promise in improving medical knowledge but have been challenging to implement within the constraints of residency training. We developed and evaluated an innovative structured format for interactive teaching within the residency noon conference. Methods We developed an ACTIVE teaching format structured around the following steps: assemble (A) into groups, convey (C) learning objectives, teach (T) background information, inquire (I) through cases and questions, verify (V) understanding, and explain (E) answer choices and educate on the learning points. We conducted a prospective, controlled study of the ACTIVE teaching format versus the standard lecture format, comparing resident satisfaction, immediate knowledge achievement and long-term knowledge retention. We qualitatively assessed participating faculty members’ perspectives on the faculty development efforts and the feasibility of teaching using the ACTIVE format. Results Sixty-nine internal medicine residents participated in the study. Overall, there was an improvement in perceived engagement using the ACTIVE teaching format (4.78 vs. 3.80, P < 0.01), with no increase in stress or decrement in break time. There was an improvement in initial knowledge achievement with the ACTIVE teaching format (overall absolute score increase of 11%, P = 0.04) and a trend toward improvement in long-term knowledge retention. Faculty members felt adequately prepared to use the ACTIVE teaching format, and enjoyed teaching with the ACTIVE teaching format more than the standard lecture. Conclusions A structured ACTIVE teaching format improved resident engagement and initial knowledge, and required minimal resources. The ACTIVE teaching format offers an exciting alternative to the standard lecture for

  18. Knowledge Requirements and Management in Expert Decision Support Systems for (Military) Situation Assessment

    DTIC Science & Technology

    1983-08-01

    constitutes a fundamental problem in many decision making processes. In business management we face this problem when determining the status of an...Tehiical Report 576 ( 1 ) 4 KNOWLEDGE REQUIREMENTS AND MANAGEMENT IN EXPERT DECISION SUPPORT SYSTEMS FOR (MILITARY) SITUATION ASSESSMENT MOOM sen...accomplished under contract for the Department of the Army The Israel Institute of Business Research Technical review by Robert H. Sasmor Joseph M

  19. Health-Related Fitness Knowledge and Physical Activity of High School Students

    ERIC Educational Resources Information Center

    Thompson, Angela; Hannon, James C.

    2012-01-01

    The purpose of this study was to determine if health-related fitness (HRF) knowledge is related to self-reported physical activity (PA) of high school students. Students (N=165) enrolled in physical education from two schools in the Southwestern U.S participated. A 100-point HRF knowledge test was assembled, focusing on the HRF concepts of…

  20. The Effects of Prior Knowledge Activation on Free Recall and Study Time Allocation.

    ERIC Educational Resources Information Center

    Machiels-Bongaerts, Maureen; And Others

    The effects of mobilizing prior knowledge on information processing were studied. Two hypotheses, the cognitive set-point hypothesis and the selective attention hypothesis, try to account for the facilitation effects of prior knowledge activation. These hypotheses predict different recall patterns as a result of mobilizing prior knowledge. In…

  1. Active Prior Tactile Knowledge Transfer for Learning Tactual Properties of New Objects

    PubMed Central

    Feng, Di

    2018-01-01

    Reusing the tactile knowledge of some previously-explored objects (prior objects) helps us to easily recognize the tactual properties of new objects. In this paper, we enable a robotic arm equipped with multi-modal artificial skin, like humans, to actively transfer the prior tactile exploratory action experiences when it learns the detailed physical properties of new objects. These experiences, or prior tactile knowledge, are built by the feature observations that the robot perceives from multiple sensory modalities, when it applies the pressing, sliding, and static contact movements on objects with different action parameters. We call our method Active Prior Tactile Knowledge Transfer (APTKT), and systematically evaluated its performance by several experiments. Results show that the robot improved the discrimination accuracy by around 10% when it used only one training sample with the feature observations of prior objects. By further incorporating the predictions from the observation models of prior objects as auxiliary features, our method improved the discrimination accuracy by over 20%. The results also show that the proposed method is robust against transferring irrelevant prior tactile knowledge (negative knowledge transfer). PMID:29466300

  2. Contemporary undergraduate physiotherapy education in terms of physical activity and exercise prescription: practice tutors' knowledge, attitudes and beliefs.

    PubMed

    O'Donoghue, Grainne; Cusack, Tara; Doody, Catherine

    2012-06-01

    Practice tutors' evaluation to (i) establish current physical activity and exercise promotion and prescription curriculum content and (ii) their knowledge, attitudes and beliefs concerning physical activity and exercise prescription in clinical education, in terms of contemporary and emerging health trends and priorities. A cross sectional survey employing a questionnaire and focus groups. All practice tutors delivering physiotherapy undergraduate education in four physiotherapy schools in Ireland (n=38) were invited to participate. Thirty participated giving a response rate of 79%. Two methods of data collection were employed. Clinical content questionnaires were administered, the results of which informed follow-up focus groups. Focus group transcriptions were analysed using the 'Framework Analysis' method. 66% of practice tutors were unhappy with their own knowledge and felt they required further training in the following areas: strategies for changing physical activity behaviour; exercise promotion and prescription for public health; exercise prescription for lifestyle related disease. Main themes emerging from the focus groups were (i) perceptions of the physiotherapist's role, (ii) perceptions of the practice tutor's role and (iii) facilitators and barriers to change. In terms of physical activity and exercise prescription education, practice tutors identified a need for further education to improve their knowledge base. However, their attitudes and beliefs relating to physiotherapists' and educators' role in terms of teaching contemporary and emerging health trends and priorities were mixed. Results of this study provide useful data to inform future physiotherapy curricula development in terms of physical activity and exercise content. Copyright © 2011 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.

  3. Information Professional or IT Professional?: The Knowledge and Skills Required by Academic Librarians in the Digital Library Environment

    ERIC Educational Resources Information Center

    Raju, Jaya

    2017-01-01

    As library and information science (LIS) becomes an increasingly technology-driven profession, particularly in the academic library environment, questions arise as to the extent of information technology (IT) knowledge and skills that LIS professionals require. The purpose of this paper is to ascertain what IT knowledge and skills are needed by…

  4. 10 CFR 490.507 - Credit activity reporting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 3 2011-01-01 2011-01-01 false Credit activity reporting requirements. 490.507 Section 490.507 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Fueled Vehicle Credit Program § 490.507 Credit activity reporting requirements. (a) A covered...

  5. 10 CFR 490.507 - Credit activity reporting requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 3 2013-01-01 2013-01-01 false Credit activity reporting requirements. 490.507 Section 490.507 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Fueled Vehicle Credit Program § 490.507 Credit activity reporting requirements. (a) A covered...

  6. 10 CFR 490.507 - Credit activity reporting requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Credit activity reporting requirements. 490.507 Section 490.507 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Fueled Vehicle Credit Program § 490.507 Credit activity reporting requirements. (a) A covered...

  7. 10 CFR 490.507 - Credit activity reporting requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 3 2012-01-01 2012-01-01 false Credit activity reporting requirements. 490.507 Section 490.507 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Fueled Vehicle Credit Program § 490.507 Credit activity reporting requirements. (a) A covered...

  8. 10 CFR 490.507 - Credit activity reporting requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 3 2014-01-01 2014-01-01 false Credit activity reporting requirements. 490.507 Section 490.507 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ALTERNATIVE FUEL TRANSPORTATION PROGRAM Alternative Fueled Vehicle Credit Program § 490.507 Credit activity reporting requirements. (a) A covered...

  9. Knowledge-acquisition tools for medical knowledge-based systems.

    PubMed

    Lanzola, G; Quaglini, S; Stefanelli, M

    1995-03-01

    Knowledge-based systems (KBS) have been proposed to solve a large variety of medical problems. A strategic issue for KBS development and maintenance are the efforts required for both knowledge engineers and domain experts. The proposed solution is building efficient knowledge acquisition (KA) tools. This paper presents a set of KA tools we are developing within a European Project called GAMES II. They have been designed after the formulation of an epistemological model of medical reasoning. The main goal is that of developing a computational framework which allows knowledge engineers and domain experts to interact cooperatively in developing a medical KBS. To this aim, a set of reusable software components is highly recommended. Their design was facilitated by the development of a methodology for KBS construction. It views this process as comprising two activities: the tailoring of the epistemological model to the specific medical task to be executed and the subsequent translation of this model into a computational architecture so that the connections between computational structures and their knowledge level counterparts are maintained. The KA tools we developed are illustrated taking examples from the behavior of a KBS we are building for the management of children with acute myeloid leukemia.

  10. Active and passive spatial learning in human navigation: acquisition of survey knowledge.

    PubMed

    Chrastil, Elizabeth R; Warren, William H

    2013-09-01

    It seems intuitively obvious that active exploration of a new environment would lead to better spatial learning than would passive visual exposure. It is unclear, however, which components of active learning contribute to spatial knowledge, and previous literature is decidedly mixed. This experiment tests the contributions of 4 components to metric survey knowledge: visual, vestibular, and podokinetic information and cognitive decision making. In the learning phase, 6 groups of participants learned the locations of 8 objects in a virtual hedge maze by (a) walking, (b) being pushed in a wheelchair, or (c) watching a video, crossed with (1) making decisions about their path or (2) being guided through the maze. In the test phase, survey knowledge was assessed by having participants walk a novel shortcut from a starting object to the remembered location of a test object, with the maze removed. Performance was slightly better than chance in the passive video condition. The addition of vestibular information did not improve performance in the wheelchair condition, but the addition of podokinetic information significantly improved angular accuracy in the walking condition. In contrast, there was no effect of decision making in any condition. The results indicate that visual and podokinetic information significantly contribute to survey knowledge, whereas vestibular information and decision making do not. We conclude that podokinetic information is the primary component of active learning for the acquisition of metric survey knowledge. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  11. Knowledge Activation, Integration, and Validation during Narrative Text Comprehension

    ERIC Educational Resources Information Center

    Cook, Anne E.; O'Brien, Edward J.

    2014-01-01

    Previous text comprehension studies using the contradiction paradigm primarily tested assumptions of the activation mechanism involved in reading. However, the nature of the contradiction in such studies relied on validation of information in readers' general world knowledge. We directly tested this validation process by varying the strength of…

  12. The Effectiveness of WhatsApp Mobile Learning Activities Guided by Activity Theory on Students' Knowledge Management

    ERIC Educational Resources Information Center

    Barhoumi, Chokri

    2015-01-01

    This research paper explores the effectiveness of using mobile technologies to support a blended learning course titled Scientific Research Methods in Information Science. Specifically, it discusses the effects of WhatsApp mobile learning activities guided by activity theory on students' knowledge Management (KM). During the 2014 academic year,…

  13. A Study of Emotions in Requirements Engineering

    NASA Astrophysics Data System (ADS)

    Colomo-Palacios, Ricardo; Hernández-López, Adrián; García-Crespo, Ángel; Soto-Acosta, Pedro

    Requirements engineering (RE) is a crucial activity in software development projects. This phase in the software development cycle is knowledge intensive, and thus, human capital intensive. From the human point of view, emotions play an important role in behavior and can even act as behavioral motivators. Thus, if we consider that RE represents a set of knowledge-intensive tasks, which include acceptance and negotiation activities, then the emotional factor represents a key element in these issues. However, the emotional factor in RE has not received the attention it deserves. This paper aims to integrate the stakeholder's emotions into the requirement process, proposing to catalogue them like any other factor in the process such as clarity or stability. Results show that high arousal and low pleasure levels are predictors of high versioning requirements.

  14. To Move More and Sit Less: Does Physical Activity/Fitness Knowledge Matter in Youth?

    ERIC Educational Resources Information Center

    Chen, Senlin; Liu, Yang; Schaben, Jodee

    2017-01-01

    Purpose: The purpose of this study was to examine physical activity (PA)/fitness knowledge and its association with PA and sedentary behavior in youth. Method: Eighth grade students from five schools (N = 660) in a midwestern state completed a PE Metrics written test and the Youth Activity Profile to assess PA/fitness knowledge, PA (at school and…

  15. Verb Aspect and the Activation of Event Knowledge

    PubMed Central

    Ferretti, Todd R.; Kutas, Marta; McRae, Ken

    2011-01-01

    The authors show that verb aspect influences the activation of event knowledge with 4 novel results. First, common locations of events (e.g., arena) are primed following verbs with imperfective aspect (e.g., was skating) but not verbs with perfect aspect (e.g., had skated). Second, people generate more locative prepositional phrases as completions to sentence fragments with imperfective than those with perfect aspect. Third, the amplitude of the N400 component to location nouns varies as a function of aspect and typicality, being smallest for imperfective sentences with highly expected locations and largest for imperfective sentences with less expected locations. Fourth, the amplitude of a sustained frontal negativity spanning prepositional phrases is larger following perfect than following imperfective aspect. Taken together, these findings suggest a dynamic interplay between event knowledge and the linguistic stream. PMID:17201561

  16. The Association between Nutrition and Physical Activity Knowledge and Weight Status of Primary School Educators

    ERIC Educational Resources Information Center

    Dalais, Lucinda; Abrahams, Zulfa; Steyn, Nelia P.; de Villiers, Anniza; Fourie, Jean M.; Hill, Jillian; Lambert, Estelle V.; Draper, Catherine E.

    2014-01-01

    The purpose of this study was to investigate primary school educators' health status, knowledge, perceptions and behaviour regarding nutrition and physical activity. Thus, nutrition and physical activity knowledge, attitudes, behaviour and risk factors for the development of non-communicable diseases of 155 educators were assessed in a…

  17. Improving Preservice Chemistry Teachers' Content Knowledge through Intervention Activities

    ERIC Educational Resources Information Center

    Wheeldon, Ruth

    2017-01-01

    The effect of intervention activities on the chemistry content knowledge of 92 preservice chemistry teachers (PSCT) was examined via a pre and post true/false with confidence level test focusing on ionisation energy values and the use of a common alternative conception (AC). Data were collected from three cohorts of PSCT each engaged in a one year…

  18. Draft position paper on knowledge management in space activities

    NASA Technical Reports Server (NTRS)

    Holm, Jeanne; Moura, Denis

    2003-01-01

    As other fields of industry, space activities are facing the challenge of Knowledge Management and the International Academy of Astronautics decided to settle in 2002 a Study Group to analyse the problem and issue general guidelines. This communication presents the draft position paper of this group in view to be discussed during the 2003 IAF Congress.

  19. Osteoporosis Knowledge, Calcium Intake, and Weight-Bearing Physical Activity in Three Age Groups of Women.

    ERIC Educational Resources Information Center

    Terrio, Kate; Auld, Garry W.

    2002-01-01

    Determined the extent and integration of osteoporosis knowledge in three age groups of women, comparing knowledge to calcium intake and weight bearing physical activity (WBPA). Overall calcium intake was relatively high. There were no differences in knowledge, calcium intake, or WBPA by age, nor did knowledge predict calcium intake and WBPA. None…

  20. Knowledge portal: a tool to capture university requirements

    NASA Astrophysics Data System (ADS)

    Mansourvar, Marjan; Binti Mohd Yasin, Norizan

    2011-10-01

    New technologies, especially, the Internet have made a huge impact on knowledge management and information dissemination in education. The web portal as a knowledge management system is very popular topics in many organizations including universities. Generally, a web portal defines as a gateway to online network accessible resources through the intranet, extranet or Internet. This study develops a knowledge portal for the students in the Faculty of Computer Science and Information Technology (FCSIT), University of Malaya (UM). The goals of this portal are to provide information for the students to help them to choose the right courses and major that are relevant to their intended future jobs or career in IT. A quantitative approach used as the selected method for this research. Quantitative method provides an easy and useful way to collect data from a large sample population.

  1. UML activity diagrams in requirements specification of logic controllers

    NASA Astrophysics Data System (ADS)

    Grobelna, Iwona; Grobelny, Michał

    2015-12-01

    Logic controller specification can be prepared using various techniques. One of them is the wide understandable and user-friendly UML language and its activity diagrams. Using formal methods during the design phase increases the assurance that implemented system meets the project requirements. In the approach we use the model checking technique to formally verify a specification against user-defined behavioral requirements. The properties are usually defined as temporal logic formulas. In the paper we propose to use UML activity diagrams in requirements definition and then to formalize them as temporal logic formulas. As a result, UML activity diagrams can be used both for logic controller specification and for requirements definition, what simplifies the specification and verification process.

  2. Clinical knowledge governance: the international perspective.

    PubMed

    Garde, Sebastian

    2013-01-01

    As a basis for semantic interoperability, ideally, a Clinical Knowledge Resource for a clinical concept should be defined formally and defined once in a way that all clinical professions and all countries can agree on. Clinical Knowledge Governance is required to create high-quality, reusable Clinical Knowledge Resources and achieve this aim. Traditionally, this is a time-consuming and cumbersome process, relying heavily on face-to-face meetings and being able to get sufficient input from clinicians. However, in a national or even international space, it is required to streamline the processes involved in creating Clinical Knowledge Resources. For this, a Web 2.0 tool that supports online collaboration of clinicians during their creation and publishing of Clinical Knowledge Resources has been developed. This tool is named the Clinical Knowledge Manager (CKM) and supports the development, review and publication of Clinical Knowledge Resources. Also, post-publication activities such as adding terminology bindings, translating the Clinical Knowledge Resource into another language and republishing it are supported. The acceptance of Clinical Knowledge Resources depends on their quality and being able to determine their quality, for example it is important to know that a broad umber of reviewers from various clinical disciplines have been involved in the development of the Clinical Knowledge Resource. We are still far from realizing the vision of a global repository of a great number of reusable, high-quality Clinical Knowledge Resources, which can provide the basis for broad semantic interoperability between systems. However progress towards this aim is being made around the world.

  3. The Effect of Prior Knowledge Activation on Text Recall: An Investigation of Two Conflicting Hypotheses.

    ERIC Educational Resources Information Center

    Machiels-Bongaerts, Maureen; And Others

    Two hypotheses, the cognitive capacity hypothesis and the selective attention hypothesis, try to account for the facilitation effects of prior knowledge activation. They appear to be mutually exclusive since they predict different recall patterns as a result of prior knowledge activation. This study was designed to determine whether the two…

  4. Effects of cardiorespiratory fitness and weight status on knowledge of physical activity and fitness, attitude toward physical education, and physical activity.

    PubMed

    Chen, Senlin; Gu, Xiangli

    2018-02-20

    The purpose of this study was to examine the effects of cardiorespiratory fitness and weight status on knowledge of physical activity and fitness (PAF knowledge), attitude toward physical education (PE), and physical activity. A total of 343 middle school students participated in the study (Age: M/SD = 12.76/.94, ranging from 11 to 14 years old). PE Metrics™ was used to measure PAF knowledge, and Attitude toward Physical Education Questionnaire and Youth Activity Profile were used to measure attitude, physical activity and sedentary behavior. Fitness and weight status were assessed using FitnessGram and converted to in Healthy Fitness Zone (HFZ) or Not in HFZ. Two-way multivariate analyses of covariance (MANCOVA; gender and grade as covariates) showed a significant group effect for cardiorespiratory fitness (Λ Pilla  = .07, F 4,255  = 5.03, p = .001, [Formula: see text] = .07) but not for weight status (p = .57). PAF knowledge (F 1,258  = 9.49, p < .01, [Formula: see text]= .04), attitude (F 1,258  = 4.45, p < .05, [Formula: see text]= .02) and sedentary behavior (F 1,258  = 6.89, p < .01, [Formula: see text]= .03) all favored the HFZ group. The findings reinforce the importance of promoting cardiorespiratory fitness in middle school PE as students acquire attitude, knowledge, and behaviors needed for active-living.

  5. Software support environment design knowledge capture

    NASA Technical Reports Server (NTRS)

    Dollman, Tom

    1990-01-01

    The objective of this task is to assess the potential for using the software support environment (SSE) workstations and associated software for design knowledge capture (DKC) tasks. This assessment will include the identification of required capabilities for DKC and hardware/software modifications needed to support DKC. Several approaches to achieving this objective are discussed and interim results are provided: (1) research into the problem of knowledge engineering in a traditional computer-aided software engineering (CASE) environment, like the SSE; (2) research into the problem of applying SSE CASE tools to develop knowledge based systems; and (3) direct utilization of SSE workstations to support a DKC activity.

  6. Importance of Self-Efficacy and Knowledge to Physical Activity Behavior in Older African Americans.

    PubMed

    Babatunde, Oyinlola Toyin

    2015-11-01

    Regular physical activity is an important lifestyle behavior for preventing or reducing the burden of osteoporosis, and for promoting optimal bone health. This report evaluates the effect of an osteoporosis education program on knowledge, self-efficacy, and initiation and/maintenance of physical activity (PA) in older African Americans. African American adults 50 years and older (n=130) were randomly assigned to either experimental (EG) or control (CG) groups. Immediately following baseline assessment EG was offered six-weekly education sessions, using the Expanded Heath Belief Model and the CG offered same after the intervention. Main outcome measures were knowledge and self-efficacy regarding osteoporosis and engagement in PA. One hundred and ten (59=EG, 51=CG) participants completed all assessments. Overall, significantly higher (p<.01) mean self-efficacy and knowledge scores were observed in the EG than in the CG. Physical activity scores were positively related to self-efficacy but not knowledge scores. Self-efficacy is important in increasing PA in older African Americans, and emphasis on culturally appropriate strategies may improve PA and reduce the risk of osteoporotic fracture.

  7. Design of customer knowledge management system for Aglaonema Nursery in South Tangerang, Indonesia

    NASA Astrophysics Data System (ADS)

    Sugiarto, D.; Mardianto, I.; Dewayana, TS; Khadafi, M.

    2017-12-01

    The purpose of this paper is to describe the design of customer knowledge management system to support customer relationship management activities for an aglaonema nursery in South Tangerang, Indonesia. System. The steps were knowledge identification (knowledge about customer, knowledge from customer, knowledge for customer), knowledge capture, codification, analysis of system requirement and create use case and activity diagram. The result showed that some key knowledge were about supporting customer in plant care (know how) and types of aglaonema including with the prices (know what). That knowledge for customer then codified and shared in knowledge portal website integrated with social media. Knowledge about customer were about customers and their behaviour in purchasing aglaonema. Knowledge from customer were about feedback, favorite and customer experience. Codified knowledge were placed and shared using content management system based on wordpress.

  8. Association between Physical Activity Knowledge and Levels of Physical Activity in Chinese Adults with Type 2 Diabetes

    PubMed Central

    Hui, Stanley Sai-Chuen; Hui, Grace Pui-Sze; Xie, Yao Jie

    2014-01-01

    Background Physical activity (PA) is an important treatment regimen for diabetes. The purposes of this study were to evaluate people’s knowledge of how exercise influences wellbeing (termed “PA knowledge” or “knowledge of PA” in this paper) and the resulting association with levels of PA in Chinese adults with Type 2 diabetes, and to identify the valuable demographic and lifestyle factors that possibly influence the association between PA knowledge and level of PA. Methods Two hundred and fifty-eight adults with Type 2 diabetes completed an interviewer-administered survey at a diabetes clinic in Hong Kong. Data on demographics, lifestyle factors and diabetes-related medical indicators were obtained. A 20-item questionnaire was developed to measure PA-related knowledge (one point scored for each correct answer; aggregate score up to 20 points). level of PA was measured by the International Physical Activity Questionnaire. Results The proportions of correct answers to each question ranged from 19.4 to 90.7%. Compared with poorly educated participants, those with university education level and above had PA knowledge scores 1.7 points higher (14.3 vs. 12.6, P<0.05). Younger, female, and obese participants were more likely to have lower level of PA (all P<0.05). After adjustment for age, gender, (BMI) and education level, the odds of having a moderate-to-high level of PA was 19% greater with 1 unit increase in PA knowledge score [95% confidence interval (CI): 1.09–1.29; P<0.001], this association was strongest in participants with tertiary education level or above [odds ratio (OR): 1.35; 95% CI: 1.03–1.77; P<0.05]. Conclusions PA knowledge was positively associated with level of PA. Education level significantly influenced the association between PA knowledge and level of PA, leading to the suggestion of vulnerable groups to target for PA improvement in the face of diabetes. PMID:25493559

  9. A Priori Knowledge and Heuristic Reasoning in Architectural Design.

    ERIC Educational Resources Information Center

    Rowe, Peter G.

    1982-01-01

    It is proposed that the various classes of a priori knowledge incorporated in heuristic reasoning processes exert a strong influence over architectural design activity. Some design problems require exercise of some provisional set of rules, inference, or plausible strategy which requires heuristic reasoning. A case study illustrates this concept.…

  10. Active and Passive Spatial Learning in Human Navigation: Acquisition of Graph Knowledge

    ERIC Educational Resources Information Center

    Chrastil, Elizabeth R.; Warren, William H.

    2015-01-01

    It is known that active exploration of a new environment leads to better spatial learning than does passive visual exposure. We ask whether specific components of active learning differentially contribute to particular forms of spatial knowledge--the "exploration-specific learning hypothesis". Previously, we found that idiothetic…

  11. Knowledge into action - supporting the implementation of evidence into practice in Scotland.

    PubMed

    Davies, Sandra; Herbert, Paul; Wales, Ann; Ritchie, Karen; Wilson, Suzanne; Dobie, Laura; Thain, Annette

    2017-03-01

    The knowledge into action model for NHS Scotland provides a framework for librarians and health care staff to support getting evidence into practice. Central to this model is the development of a network of knowledge brokers to facilitate identification, use, creation and sharing of knowledge. To translate the concepts described in the model into tangible activities with the intention of supporting better use of evidence in health care and subsequently improving patient outcomes. Four areas of activity were addressed by small working groups comprising knowledge services staff in local and national boards. The areas of activity were as follows: defining existing and required capabilities and developing learning opportunities for the knowledge broker network; establishing national search and summarising services; developing actionable knowledge tools; and supporting person-to-person knowledge sharing. This work presents the development of practical tools and support to translate a conceptual model for getting knowledge into action into a series of activities and outputs to support better use of evidence in health care and subsequently improved patient outcomes. © 2017 Health Libraries Group.

  12. Ubiquitous Mobile Knowledge Construction in Collaborative Learning Environments

    PubMed Central

    Baloian, Nelson; Zurita, Gustavo

    2012-01-01

    Knowledge management is a critical activity for any organization. It has been said to be a differentiating factor and an important source of competitiveness if this knowledge is constructed and shared among its members, thus creating a learning organization. Knowledge construction is critical for any collaborative organizational learning environment. Nowadays workers must perform knowledge creation tasks while in motion, not just in static physical locations; therefore it is also required that knowledge construction activities be performed in ubiquitous scenarios, and supported by mobile and pervasive computational systems. These knowledge creation systems should help people in or outside organizations convert their tacit knowledge into explicit knowledge, thus supporting the knowledge construction process. Therefore in our understanding, we consider highly relevant that undergraduate university students learn about the knowledge construction process supported by mobile and ubiquitous computing. This has been a little explored issue in this field. This paper presents the design, implementation, and an evaluation of a system called MCKC for Mobile Collaborative Knowledge Construction, supporting collaborative face-to-face tacit knowledge construction and sharing in ubiquitous scenarios. The MCKC system can be used by undergraduate students to learn how to construct knowledge, allowing them anytime and anywhere to create, make explicit and share their knowledge with their co-learners, using visual metaphors, gestures and sketches to implement the human-computer interface of mobile devices (PDAs). PMID:22969333

  13. Ubiquitous mobile knowledge construction in collaborative learning environments.

    PubMed

    Baloian, Nelson; Zurita, Gustavo

    2012-01-01

    Knowledge management is a critical activity for any organization. It has been said to be a differentiating factor and an important source of competitiveness if this knowledge is constructed and shared among its members, thus creating a learning organization. Knowledge construction is critical for any collaborative organizational learning environment. Nowadays workers must perform knowledge creation tasks while in motion, not just in static physical locations; therefore it is also required that knowledge construction activities be performed in ubiquitous scenarios, and supported by mobile and pervasive computational systems. These knowledge creation systems should help people in or outside organizations convert their tacit knowledge into explicit knowledge, thus supporting the knowledge construction process. Therefore in our understanding, we consider highly relevant that undergraduate university students learn about the knowledge construction process supported by mobile and ubiquitous computing. This has been a little explored issue in this field. This paper presents the design, implementation, and an evaluation of a system called MCKC for Mobile Collaborative Knowledge Construction, supporting collaborative face-to-face tacit knowledge construction and sharing in ubiquitous scenarios. The MCKC system can be used by undergraduate students to learn how to construct knowledge, allowing them anytime and anywhere to create, make explicit and share their knowledge with their co-learners, using visual metaphors, gestures and sketches to implement the human-computer interface of mobile devices (PDAs).

  14. Effects of Activation of Prior Knowledge on the Recall of a Clinical Case.

    ERIC Educational Resources Information Center

    Schmidt, Henk G.; Boshuizen, Henny P. A.

    A study investigated the known phenomenon of "intermediate effect" in which medical students with an intermediate amount of knowledge and experience demonstrate higher amounts of recall of the text of a medical case than either experienced clinicians or novices. In this study the amount of activation of prior knowledge was controlled by…

  15. Knowledge representation of motor activity of patients with Parkinson's disease.

    PubMed

    Kostek, Bożena; Kupryjanow, Adam; Czyżewski, Andrzej

    An approach to the knowledge representation extraction from biomedical signals analysis concerning motor activity of Parkinson disease patients is proposed in this paper. This is done utilizing accelerometers attached to their body as well as exploiting video image of their hand movements. Experiments are carried out employing artificial neural networks and support vector machine to the recognition of characteristic motor activity disorders in patients. Obtained results indicate that it is possible to interpret some selected patient's body movements with a sufficiently high effectiveness.

  16. Knowledge-based environment for optical system design

    NASA Astrophysics Data System (ADS)

    Johnson, R. Barry

    1991-01-01

    Optical systems are extensively utilized by industry government and military organizations. The conceptual design engineering design fabrication and testing of these systems presently requires significant time typically on the order of 3-5 years. The Knowledge-Based Environment for Optical System Design (KB-OSD) Program has as its principal objectives the development of a methodology and tool(s) that will make a notable reduction in the development time of optical system projects reduce technical risk and overall cost. KB-OSD can be considered as a computer-based optical design associate for system engineers and design engineers. By utilizing artificial intelligence technology coupled with extensive design/evaluation computer application programs and knowledge bases the KB-OSD will provide the user with assistance and guidance to accomplish such activities as (i) develop system level and hardware level requirements from mission requirements (ii) formulate conceptual designs (iii) construct a statement of work for an RFP (iv) develop engineering level designs (v) evaluate an existing design and (vi) explore the sensitivity of a system to changing scenarios. The KB-OSD comprises a variety of computer platforms including a Stardent Titan supercomputer numerous design programs (lens design coating design thermal materials structural atmospherics etc. ) data bases and heuristic knowledge bases. An important element of the KB-OSD Program is the inclusion of the knowledge of individual experts in various areas of optics and optical system engineering. This knowledge is obtained by KB-OSD knowledge engineers performing

  17. Active and Passive Spatial Learning in Human Navigation: Acquisition of Survey Knowledge

    ERIC Educational Resources Information Center

    Chrastil, Elizabeth R.; Warren, William H.

    2013-01-01

    It seems intuitively obvious that active exploration of a new environment would lead to better spatial learning than would passive visual exposure. It is unclear, however, which components of active learning contribute to spatial knowledge, and previous literature is decidedly mixed. This experiment tests the contributions of 4 components to…

  18. AIDS knowledge and sexual activity among Flemish secondary school students: a multilevel analysis of the effects of type of education.

    PubMed

    Van Rossem, Ronan; Berten, Hans; Van Tuyckom, Charlotte

    2010-01-21

    The behavior of adolescents puts them at an increased risk for HIV and other STIs, and their knowledge about HIV/AIDS is often inadequate. An understanding of how AIDS knowledge and sexual activity co-vary among Flemish secondary school students and of how education type, specifically, affects these students is limited. This study addresses the question of whether the effects of education type on HIV/AIDS knowledge and sexual activity are independent of the socio-demographic characteristics of the students. Data from the Flemish Educational Assessment survey, which collected data from a large representative sample of third- and fifth-grade high school students (N = 11,872), were used. Data were analyzed using multilevel logistic and Poisson regression techniques. There is an indication that type of education affects both an adolescent's sexual activity and his/her AIDS knowledge; these effects prove robust for differences in socio-economic backgrounds. Students in lower status education types are more likely to be sexually active and to have poorer AIDS knowledge. The relationship between AIDS knowledge and sexual activity is, however, more complex. Although students in education types with poorer AIDS knowledge are more sexually active, within each of these groups the sexually active have better AIDS knowledge than the non-sexually active. There is also evidence of active information seeking by sexually active students, which leads to improved AIDS knowledge. These findings are consistent with the literature on the role of the educational system in the reproduction of social inequalities. Students from lower status education types are at increased sexual risk compared to those from higher status types. There is also evidence of active information seeking by sexually active students, which leads to improved AIDS knowledge.

  19. An active-learning assignment requiring pharmacy students to write medicinal chemistry examination questions.

    PubMed

    Kolluru, Srikanth

    2012-08-10

    To implement and assess the effectiveness of an assignment requiring doctor of pharmacy (PharmD) students to write examination questions for the medicinal chemistry sections of a pharmacotherapeutics course. Students were divided into groups of 5-6 and given detailed instructions and grading rubrics for writing multiple-choice examination questions on medicinal chemistry topics. The compiled student-written questions for each examination were provided to the entire class as a study aid. Approximately 5% of the student-written questions were used in course examinations. Student appreciation of and performance in the medicinal chemistry portion of the course was significantly better than that of the previous year's class. Also, students' responses on a qualitative survey instrument indicated that the assignment provided students' guidance on which concepts to focus on, helped them retain knowledge better, and fostered personal exploration of the content, which led to better performance on examinations. Adding an active-learning assignment in which students write examination questions for the medicinal chemistry portion of a pharmacotherapeutics course was an effective means of increasing students engagement in the class and knowledge of the course material.

  20. Assessment of weight status, dietary habits and beliefs, physical activity, and nutritional knowledge among university students.

    PubMed

    Yahia, Najat; Wang, Daniel; Rapley, Melyssa; Dey, Rajarshi

    2016-07-01

    The purpose of this study was to assess weight status, dietary habits, physical activity, dietary beliefs, and nutrition knowledge among a sample of students from Central Michigan University. A cross-sectional survey was conducted among a sample of undergraduate students in Fall 2011 and Spring 2012 at Central Michigan University. Participating students completed an online questionnaire that included questions related to their eating habits, physical activity and lifestyle, dietary beliefs, and nutritional knowledge. Weight, height, and waist circumference were measured. Percentage body fat and visceral fat score were determined using a Tanita body composition analyser (SC-331S). Outcomes of this study indicated that 78% of female students were within the healthy weight range compared to 52% of male students. Visceral body fat and waist circumference scores were higher in males than in females. Most students showed 'satisfactory' dietary habits. Almost half of the students reported drinking two glasses of milk and consuming two cups of fruits and vegetables daily. Physical activity and lifestyle score indicated that most of the students were not physically active. Only 7% of students reported having a very active lifestyle, and 4% had quite good nutritional knowledge. The majority of students, particularly females, were within the healthy body weight range. Students' dietary habits were satisfactory. However, physical activity, students' knowledge of healthy and unhealthy diet habits, and nutritional knowledge needed improvement. Developing gender-specific programmes for promoting healthy lifestyle behaviours among students is recommended. © Royal Society for Public Health 2015.

  1. Comparing Two Forms of Concept Map Critique Activities to Facilitate Knowledge Integration Processes in Evolution Education

    ERIC Educational Resources Information Center

    Schwendimann, Beat A.; Linn, Marcia C.

    2016-01-01

    Concept map activities often lack a subsequent revision step that facilitates knowledge integration. This study compares two collaborative critique activities using a Knowledge Integration Map (KIM), a form of concept map. Four classes of high school biology students (n?=?81) using an online inquiry-based learning unit on evolution were assigned…

  2. "What-Where-Which" Episodic Retrieval Requires Conscious Recollection and Is Promoted by Semantic Knowledge

    PubMed Central

    Saive, Anne-Lise; Royet, Jean-Pierre; Garcia, Samuel; Thévenet, Marc; Plailly, Jane

    2015-01-01

    Episodic memory is defined as the conscious retrieval of specific past events. Whether accurate episodic retrieval requires a recollective experience or if a feeling of knowing is sufficient remains unresolved. We recently devised an ecological approach to investigate the controlled cued-retrieval of episodes composed of unnamable odors (What) located spatially (Where) within a visual context (Which context). By combining the Remember/Know procedure with our laboratory-ecological approach in an original way, the present study demonstrated that the accurate odor-evoked retrieval of complex and multimodal episodes overwhelmingly required conscious recollection. A feeling of knowing, even when associated with a high level of confidence, was not sufficient to generate accurate episodic retrieval. Interestingly, we demonstrated that the recollection of accurate episodic memories was promoted by odor retrieval-cue familiarity and describability. In conclusion, our study suggested that semantic knowledge about retrieval-cues increased the recollection which is the state of awareness required for the accurate retrieval of complex episodic memories. PMID:26630170

  3. "What-Where-Which" Episodic Retrieval Requires Conscious Recollection and Is Promoted by Semantic Knowledge.

    PubMed

    Saive, Anne-Lise; Royet, Jean-Pierre; Garcia, Samuel; Thévenet, Marc; Plailly, Jane

    2015-01-01

    Episodic memory is defined as the conscious retrieval of specific past events. Whether accurate episodic retrieval requires a recollective experience or if a feeling of knowing is sufficient remains unresolved. We recently devised an ecological approach to investigate the controlled cued-retrieval of episodes composed of unnamable odors (What) located spatially (Where) within a visual context (Which context). By combining the Remember/Know procedure with our laboratory-ecological approach in an original way, the present study demonstrated that the accurate odor-evoked retrieval of complex and multimodal episodes overwhelmingly required conscious recollection. A feeling of knowing, even when associated with a high level of confidence, was not sufficient to generate accurate episodic retrieval. Interestingly, we demonstrated that the recollection of accurate episodic memories was promoted by odor retrieval-cue familiarity and describability. In conclusion, our study suggested that semantic knowledge about retrieval-cues increased the recollection which is the state of awareness required for the accurate retrieval of complex episodic memories.

  4. Impact of a Required Pharmaceutical Calculations Course on Mathematics Ability and Knowledge Retention

    PubMed Central

    Buring, Shauna M.; Papas, Elizabeth

    2013-01-01

    Objective. To assess doctor of pharmacy (PharmD) students’ mathematics ability by content area before and after completing a required pharmaceutical calculations course and to analyze changes in scores. Methods. A mathematics skills assessment was administered to 2 cohorts of pharmacy students (class of 2013 and 2014) before and after completing a pharmaceutical calculations course. The posttest was administered to the second cohort 6 months after completing the course to assess knowledge retention. Results. Both cohorts performed significantly better on the posttest (cohort 1, 13% higher scores; cohort 2, 15.9% higher scores). Significant improvement on posttest scores was observed in 6 of the 10 content areas for cohorts 1 and 2. Both cohorts scored lower in percentage calculations on the posttest than on the pretest. Conclusions. A required, 1-credit-hour pharmaceutical calculations course improved PharmD students’ overall ability to perform fundamental and application-based calculations. PMID:23966727

  5. Impact of a required pharmaceutical calculations course on mathematics ability and knowledge retention.

    PubMed

    Hegener, Michael A; Buring, Shauna M; Papas, Elizabeth

    2013-08-12

    To assess doctor of pharmacy (PharmD) students' mathematics ability by content area before and after completing a required pharmaceutical calculations course and to analyze changes in scores. A mathematics skills assessment was administered to 2 cohorts of pharmacy students (class of 2013 and 2014) before and after completing a pharmaceutical calculations course. The posttest was administered to the second cohort 6 months after completing the course to assess knowledge retention. Both cohorts performed significantly better on the posttest (cohort 1, 13% higher scores; cohort 2, 15.9% higher scores). Significant improvement on posttest scores was observed in 6 of the 10 content areas for cohorts 1 and 2. Both cohorts scored lower in percentage calculations on the posttest than on the pretest. A required, 1-credit-hour pharmaceutical calculations course improved PharmD students' overall ability to perform fundamental and application-based calculations.

  6. Tracking real-time neural activation of conceptual knowledge using single-trial event-related potentials.

    PubMed

    Amsel, Ben D

    2011-04-01

    Empirically derived semantic feature norms categorized into different types of knowledge (e.g., visual, functional, auditory) can be summed to create number-of-feature counts per knowledge type. Initial evidence suggests several such knowledge types may be recruited during language comprehension. The present study provides a more detailed understanding of the timecourse and intensity of influence of several such knowledge types on real-time neural activity. A linear mixed-effects model was applied to single trial event-related potentials for 207 visually presented concrete words measured on total number of features (semantic richness), imageability, and number of visual motion, color, visual form, smell, taste, sound, and function features. Significant influences of multiple feature types occurred before 200ms, suggesting parallel neural computation of word form and conceptual knowledge during language comprehension. Function and visual motion features most prominently influenced neural activity, underscoring the importance of action-related knowledge in computing word meaning. The dynamic time courses and topographies of these effects are most consistent with a flexible conceptual system wherein temporally dynamic recruitment of representations in modal and supramodal cortex are a crucial element of the constellation of processes constituting word meaning computation in the brain. Copyright © 2011 Elsevier Ltd. All rights reserved.

  7. Student knowledge and confidence in an elective clinical toxicology course using active-learning techniques.

    PubMed

    Thomas, Michael C; Macias-Moriarity, Liliairica Z

    2014-06-17

    To measure changes in students' knowledge and confidence scores after completing an elective clinical toxicology course in an accelerated doctor of pharmacy (PharmD) program. Various active-learning techniques were used to create a learner-centered environment. Approximately two-thirds of the course used student-led presentations. Some of those not presenting were assigned to be evaluators, responsible for asking the presenter a question or writing quiz questions based on the presented material. Other learner-centered activities included weekly quizzes and discussions at the conclusion of each presented topic. A test instrument designed to measure students' knowledge and associated level of confidence on each item was administered at the beginning and end of the course. Students' knowledge and confidence scores increased significantly from pretest to posttest. Students' increased confidence and knowledge scores were well correlated after course completion, indicating students were better able to self-assess these areas. These findings suggest that confidence could be an additional measure of students' metacognitive skill development.

  8. A Web-based Multimedia Program Before Colonoscopy Increased Knowledge and Decreased Anxiety, Sedation Requirement, and Procedure Time.

    PubMed

    Parker, Siddhartha; Zipursky, Jonathan; Ma, Helen; Baumblatt, Geri-Lynn; Siegel, Corey A

    2018-07-01

    Assess the impact of a web-based multimedia patient engagement program on patient anxiety, perception and knowledge about the colonoscopy in addition to procedure outcomes. The success of patients coming for a colonoscopy for colorectal cancer screening is dependent in part on patients' understanding of the preparation and of the procedure. Patients were randomized to use either our institution's standard preprocedure colonoscopy packet or a web-based multimedia patient engagement program (Emmi Solutions) before their scheduled procedure. On the day of colonoscopy, all participants completed a survey including questions to assess knowledge and perception of colonoscopy, in addition to the State Trait Anxiety Inventory. We also collected procedure data including medication doses and procedure time. Patients in the experimental group correctly answered knowledge questions (82%) more often than the control group (74%) (P=0.0003). More than half (58%) of patients in the experimental group felt this intervention reduced their anxiety about the procedure, and the State Trait Anxiety Inventory anxiety score was lower in the experimental group (P=0.026). Patients who viewed the program required less midazolam (3.66 vs. 4.46 mg, P=0.0035) and total procedure time was shorter (24.8 vs. 29 min, P=0.024). A web-based multimedia patient engagement program watched before colonoscopy decreased patient anxiety, medication requirements, and procedure time while increasing knowledge. This intervention could help patients understand and feel more comfortable about colonoscopy leading to increased screening rates while increasing efficiency and decreasing recovery time.

  9. An active learning curriculum improves fellows' knowledge and faculty teaching skills.

    PubMed

    Inra, Jennifer A; Pelletier, Stephen; Kumar, Navin L; Barnes, Edward L; Shields, Helen M

    2017-01-01

    Traditional didactic lectures are the mainstay of teaching for graduate medical education, although this method may not be the most effective way to transmit information. We created an active learning curriculum for Brigham and Women's Hospital (BWH) gastroenterology fellows to maximize learning. We evaluated whether this new curriculum improved perceived knowledge acquisition and knowledge base. In addition, our study assessed whether coaching faculty members in specific methods to enhance active learning improved their perceived teaching and presentation skills. We compared the Gastroenterology Training Exam (GTE) scores before and after the implementation of this curriculum to assess whether an improved knowledge base was documented. In addition, fellows and faculty members were asked to complete anonymous evaluations regarding their learning and teaching experiences. Fifteen fellows were invited to 12 lectures over a 2-year period. GTE scores improved in the areas of stomach ( p <0.001), general gastroenterology ( p =0.005), esophagus ( p <0.001), and small bowel ( p =0.001), and the total score ( p =0.001) between pre- and postimplementation of the active learning curriculum. Scores in hepatology, as well as biliary and pancreatic study, showed a trend toward improvement ( p >0.05). All fellows believed the lectures were helpful, felt more prepared to take the GTE, and preferred the interactive format to traditional didactic lectures. All lecturers agreed that they acquired new teaching skills, improved teaching and presentation skills, and learned new tools that could help them teach better in the future. An active learning curriculum is preferred by GI fellows and may be helpful for improving transmission of information in any specialty in medical education. Individualized faculty coaching sessions demonstrating new ways to transmit information may be important for an individual faculty member's teaching excellence.

  10. Development of an Inquiry-Based Learning Support System Based on an Intelligent Knowledge Exploration Approach

    ERIC Educational Resources Information Center

    Wu, Ji-Wei; Tseng, Judy C. R.; Hwang, Gwo-Jen

    2015-01-01

    Inquiry-Based Learning (IBL) is an effective approach for promoting active learning. When inquiry-based learning is incorporated into instruction, teachers provide guiding questions for students to actively explore the required knowledge in order to solve the problems. Although the World Wide Web (WWW) is a rich knowledge resource for students to…

  11. Gender, Religiosity, Sexual Activity, Sexual Knowledge, and Attitudes Toward Controversial Aspects of Sexuality.

    PubMed

    Sümer, Zeynep Hatipoğlu

    2015-12-01

    The purpose of this study is to examine the role of gender, religiosity, sexual activity, and sexual knowledge in predicting attitudes toward controversial aspects of sexuality among Turkish university students. Participants were 162 female and 135 male undergraduate students who were recruited on a volunteer basis from an urban state university in Turkey. The SKAT-A Attitude Scale along with background information form, sexual activities inventory, and sexual knowledge scale were administered to the participants. Simultaneous multiple regression analyses revealed that religiosity, particularly attendance to religious services was the most significant predictor in explaining university students' attitudes toward masturbation, abortion, homosexuality, pornography, and sexual coercion.

  12. On the comparability of knowledge transfer activities - a case study at the German Baltic Sea Coast focusing regional climate services

    NASA Astrophysics Data System (ADS)

    Meinke, Insa

    2017-06-01

    In this article the comparability of knowledge transfer activities is discussed by accounting for external impacts. It is shown that factors which are neither part of the knowledge transfer activity nor part of the participating institution may have significant impact on the potential usefulness of knowledge transfer activities. Differences in the potential usefulness are leading to different initial conditions of the knowledge transfer activities. This needs to be taken into account when comparing different knowledge transfer activities, e.g., in program evaluations. This study is focusing on regional climate services at the German Baltic Sea coast. It is based on two surveys and experiences with two identical web tools applied on two regions with different spatial coverage. The results show that comparability among science based knowledge transfer activities is strongly limited through several external impacts. The potential usefulness and thus the initial condition of a particular knowledge transfer activity strongly depends on (1) the perceived priority of the focused topic, (2) the used information channels, (3) the conformity between the research agenda of service providing institutions and information demands in the public, as well as (4) on the spatial coverage of a service. It is suggested to account for the described external impacts for evaluations of knowledge transfer activities. The results show that the comparability of knowledge transfer activities is limited and challenge the adequacy of quantitative measures in this context. Moreover, as shown in this case study, in particular regional climate services should be individually evaluated on a long term perspective, by potential user groups and/or by its real users. It is further suggested that evaluation criteria should be co-developed with these stakeholder groups.

  13. Integrating the Use of Interdisciplinary Learning Activity Task in Creating Students' Mathematical Knowledge

    ERIC Educational Resources Information Center

    Mahanin, Hajah Umisuzimah Haji; Shahrill, Masitah; Tan, Abby; Mahadi, Mar Aswandi

    2017-01-01

    This study investigated the use of interdisciplinary learning activity task to construct students' knowledge in Mathematics, specifically on the topic of scale drawing application. The learning activity task involved more than one academic discipline, which is Mathematics, English Language, Art, Geography and integrating the Brunei Darussalam…

  14. Community Knowledge about Water: Who Has Better Knowledge and Is This Associated with Water-Related Behaviors and Support for Water-Related Policies?

    PubMed Central

    Fielding, Kelly S.; Newton, Fiona J.

    2016-01-01

    Sustainable approaches to water management require broad community acceptance of changes in policy, practice and technology, which in turn, requires an engaged community. A critical first step in building an engaged community is to identify community knowledge about water management, an issue rarely examined in research. To address this, we surveyed a representative sample of Australian adults (n = 5172). Knowledge was assessed using 15 questions about impact of household activities on waterways, the urban water cycle, and water management. This survey also examined demographics, psychosocial characteristics, exposure to water-related information, and water-related behaviors and policy support. Participants correctly answered a mean of 8.0 questions (Range 0–15). Most respondents knew that household actions can reduce water use and influence waterway health, whereas less than one third correctly identified that domestic wastewater is treated prior to entering waterways, urban stormwater is not treated, and that these are carried via different pipes. Higher water knowledge was associated with older age, higher education and living in non-urban areas. Poorer water knowledge was associated with speaking a language other than English in the home. Garden size, experience of water restrictions, satisfaction, waterway use for swimming, and certain information sources were also associated with knowledge. Greater water knowledge was associated with adoption of water-saving and pollution-reduction behaviors, and support for both alternative water sources and raingardens. These findings confirm the importance of community knowledge, and identify potential subgroups who may require additional targeting to build knowledge and support for water management initiatives. PMID:27428372

  15. Community Knowledge about Water: Who Has Better Knowledge and Is This Associated with Water-Related Behaviors and Support for Water-Related Policies?

    PubMed

    Dean, Angela J; Fielding, Kelly S; Newton, Fiona J

    2016-01-01

    Sustainable approaches to water management require broad community acceptance of changes in policy, practice and technology, which in turn, requires an engaged community. A critical first step in building an engaged community is to identify community knowledge about water management, an issue rarely examined in research. To address this, we surveyed a representative sample of Australian adults (n = 5172). Knowledge was assessed using 15 questions about impact of household activities on waterways, the urban water cycle, and water management. This survey also examined demographics, psychosocial characteristics, exposure to water-related information, and water-related behaviors and policy support. Participants correctly answered a mean of 8.0 questions (Range 0-15). Most respondents knew that household actions can reduce water use and influence waterway health, whereas less than one third correctly identified that domestic wastewater is treated prior to entering waterways, urban stormwater is not treated, and that these are carried via different pipes. Higher water knowledge was associated with older age, higher education and living in non-urban areas. Poorer water knowledge was associated with speaking a language other than English in the home. Garden size, experience of water restrictions, satisfaction, waterway use for swimming, and certain information sources were also associated with knowledge. Greater water knowledge was associated with adoption of water-saving and pollution-reduction behaviors, and support for both alternative water sources and raingardens. These findings confirm the importance of community knowledge, and identify potential subgroups who may require additional targeting to build knowledge and support for water management initiatives.

  16. Development of an expert system prototype for determining software functional requirements for command management activities at NASA Goddard

    NASA Technical Reports Server (NTRS)

    Liebowitz, J.

    1986-01-01

    The development of an expert system prototype for software functional requirement determination for NASA Goddard's Command Management System, as part of its process of transforming general requests into specific near-earth satellite commands, is described. The present knowledge base was formulated through interactions with domain experts, and was then linked to the existing Knowledge Engineering Systems (KES) expert system application generator. Steps in the knowledge-base development include problem-oriented attribute hierarchy development, knowledge management approach determination, and knowledge base encoding. The KES Parser and Inspector, in addition to backcasting and analogical mapping, were used to validate the expert system-derived requirements for one of the major functions of a spacecraft, the solar Maximum Mission. Knowledge refinement, evaluation, and implementation procedures of the expert system were then accomplished.

  17. 20 CFR 665.200 - What are required Statewide workforce investment activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... investment activities? 665.200 Section 665.200 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR STATEWIDE WORKFORCE INVESTMENT ACTIVITIES UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Required and Allowable Statewide Workforce Investment Activities § 665.200 What are required Statewide...

  18. Impact of interprofessional activities on health professions students' knowledge of community pharmacists' role and services.

    PubMed

    Vrontos, Emily B; Kuhn, Catherine H; Brittain, Kristy L

    2011-10-10

    To determine the impact of health professions students' participation in interprofessional activities on their knowledge of the roles of community pharmacists and community pharmacist-provided services. Students at the Medical University of South Carolina were surveyed via a self-administered online survey tool to determine their participation in interprofessional activities as well as their knowledge of the role of community pharmacists and community pharmacist-provided services. Over 600 students completed the survey instrument. Nonpharmacy students who attended the university-sponsored Interprofessional Day were more knowledgeable of pharmacist-provided services. Previous interaction with a pharmacist increased nonpharmacy students' awareness of the services that pharmacists provide. Participation in interprofessional activities increased health professions students' awareness of the role of pharmacists. Continued education among healthcare professions about the role of and services provided by pharmacists is needed to ensure that pharmacists have the greatest possible impact on patient care.

  19. Knowledge management: an application to wildfire prevention planning

    Treesearch

    Daniel L Schmoldt

    1989-01-01

    Residential encroachment into wildland areas places an additional burden on fire management activities. Prevention programs, fuel management efforts, and suppression strategies, previously employed in wildland areas, require modification for protection of increased values at risk in this interface area. Knowledge-based computer systems are being investigated as...

  20. The Nuclear Energy Knowledge and Validation Center – Summary of Activities Conducted in FY15

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gougar, Hans David; Hong, Bonnie Colleen

    2016-05-01

    The Nuclear Energy Knowledge and Validation Center (NEKVaC) is a new initiative by the Department of Energy and the Idaho National Laboratory to coordinate and focus the resources and expertise that exist with the DOE Complex toward solving issues in modern nuclear code validation. In time, code owners, users, and developers will view the Center as a partner and essential resource for acquiring the best practices and latest techniques for validating codes, for guidance in planning and executing experiments, for facilitating access to, and maximizing the usefulness of, existing data, and for preserving knowledge for continual use by nuclear professionalsmore » and organizations for their own validation needs. The scope of the center covers many inter-related activities which will need to be cultivated carefully in the near-term and managed properly once the Center is fully functional. Three areas comprise the principal mission: 1) identification and prioritization of projects that extend the field of validation science and its application to modern codes, 2) adapt or develop best practices and guidelines for high fidelity multiphysics/multiscale analysis code development and associated experiment design, and 3) define protocols for data acquisition and knowledge preservation and provide a portal for access to databases currently scattered among numerous organizations. These mission areas, while each having a unique focus, are inter-dependent and complementary. Likewise, all activities supported by the NEKVaC, both near-term and long-term), must possess elements supporting all three. This cross-cutting nature is essential to ensuring that activities and supporting personnel do not become ‘stove-piped’, i.e. focused so much on a specific function that the activity itself becomes the objective rather than the achieving the larger vision. Achieving the broader vision will require a healthy and accountable level of activity in each of the areas. This will take time

  1. Enhancing Primary School Students' Knowledge about Global Warming and Environmental Attitude Using Climate Change Activities

    NASA Astrophysics Data System (ADS)

    Karpudewan, Mageswary; Roth, Wolff-Michael; Abdullah, Mohd Nor Syahrir Bin

    2015-01-01

    Climate change generally and global warming specifically have become a common feature of the daily news. Due to widespread recognition of the adverse consequences of climate change on human lives, concerted societal effort has been taken to address it (e.g. by means of the science curriculum). This study was designed to test the effect that child-centred, 5E learning cycle-based climate change activities would have over more traditional teacher-centred activities on Malaysian Year 5 primary students (11 years). A quasi-experimental design involving a treatment (n = 55) and a group representing typical teaching method (n = 60) was used to measure the effectiveness of these activities on (a) increasing children's knowledge about global warming; (b) changing their attitudes to be more favourable towards the environment and (c) identify the relationship between knowledge and attitude that exist in this study. Statistically significant differences in favour of the treatment group were detected for both knowledge and environmental attitudes. Non-significant relationship was identified between knowledge and attitude in this study. Interviews with randomly selected students from treatment and comparison groups further underscore these findings. Implications are discussed.

  2. Elementary Physical Education Teachers' Content Knowledge of Physical Activity and Health-Related Fitness

    ERIC Educational Resources Information Center

    Santiago, Jose A.; Disch, James G.; Morales, Julio

    2012-01-01

    The purpose of this study was to examine elementary physical education teachers' content knowledge of physical activity and health-related fitness. Sixty-four female and 24 male teachers completed the Appropriate Physical Activity and Health-Related Fitness test. Descriptive statistics results indicated that the mean percentage score for the test…

  3. Management of Knowledge Representation Standards Activities

    NASA Technical Reports Server (NTRS)

    Patil, Ramesh S.

    1993-01-01

    Ever since the mid-seventies, researchers have recognized that capturing knowledge is the key to building large and powerful AI systems. In the years since, we have also found that representing knowledge is difficult and time consuming. In spite of the tools developed to help with knowledge acquisition, knowledge base construction remains one of the major costs in building an Al system: For almost every system we build, a new knowledge base must be constructed from scratch. As a result, most systems remain small to medium in size. Even if we build several systems within a general area, such as medicine or electronics diagnosis, significant portions of the domain must be represented for every system we create. The cost of this duplication of effort has been high and will become prohibitive as we attempt to build larger and larger systems. To overcome this barrier we must find ways of preserving existing knowledge bases and of sharing, re-using, and building on them. This report describes the efforts undertaken over the last two years to identify the issues underlying the current difficulties in sharing and reuse, and a community wide initiative to overcome them. First, we discuss four bottlenecks to sharing and reuse, present a vision of a future in which these bottlenecks have been ameliorated, and describe the efforts of the initiative's four working groups to address these bottlenecks. We then address the supporting technology and infrastructure that is critical to enabling the vision of the future. Finally, we consider topics of longer-range interest by reviewing some of the research issues raised by our vision.

  4. A modal H∞-norm-based performance requirement for damage-tolerant active controller design

    NASA Astrophysics Data System (ADS)

    Genari, Helói F. G.; Mechbal, Nazih; Coffignal, Gérard; Nóbrega, Eurípedes G. O.

    2017-04-01

    Damage-tolerant active control (DTAC) is a recent research area that encompasses control design methodologies resulting from the application of fault-tolerant control methods to vibration control of structures subject to damage. The possibility of damage occurrence is not usually considered in the active vibration control design requirements. Damage changes the structure dynamics, which may produce unexpected modal behavior of the closed-loop system, usually not anticipated by the controller design approaches. A modal H∞ norm and a respective robust controller design framework were recently introduced, and this method is here extended to face a new DTAC strategy implementation. Considering that damage affects each vibration mode differently, this paper adopts the modal H∞ norm to include damage as a design requirement. The basic idea is to create an appropriate energy distribution over the frequency range of interest and respective vibration modes, guaranteeing robustness, damage tolerance, and adequate overall performance, taking into account that it is common to have previous knowledge of the structure regions where damage may occur during its operational life. For this purpose, a structural health monitoring technique is applied to evaluate modal modifications caused by damage. This information is used to create modal weighing matrices, conducting to the modal H∞ controller design. Finite element models are adopted for a case study structure, including different damage severities, in order to validate the proposed control strategy. Results show the effectiveness of the proposed methodology with respect to damage tolerance.

  5. Required Preliminary Administrative Service Credential Program Culminating Activities in California NCATE Accredited Universities

    ERIC Educational Resources Information Center

    Wildman, Louis

    2014-01-01

    The purpose of this effort is to share information about the variety of culminating activities used in the acquisition of the California Preliminary Administrative Services Credential. Knowledge of these varying culminating activities and related practices has not previously been readily available. The culminating activities among California's…

  6. Validation of an iPad activity to measure preschool children's food and physical activity knowledge and preferences.

    PubMed

    Wiseman, Nicola; Harris, Neil; Downes, Martin

    2017-02-01

    Preschool children's knowledge of, and preference for food and physical activity play an important role in the development of lifestyle behaviors throughout childhood. Valid and reliable instruments that are interactive and appealing to preschool children are needed, to obtain quality information in a way that actively engages children and encourages willing participation. The purpose of the current research is to assess the reliability and validity of an adapted computerized (iPad) version of the photo-pair food and exercise questionnaire (PPFEQ). The adaptation of the PPFEQ involved generating the questionnaire as an iPad-based tool, updating the photo-pairs within the questionnaire and testing for validity and reliability. This involved four phases of investigation to assess test-retest reliability, internal consistency, sensitivity to change and percent agreement of the questionnaire. The adaption of the PPFEQ resulted in an 18-item questionnaire, titled the preschool food and play questionnaire (Pre-FPQ). The Pre-FPQ demonstrated acceptable reliability and sensitivity to change. Test-retest reliability and internal consistency improved with age, however, it was evident that the tool was not suitable for children younger than 4 years of age. Children encounter a dynamic world that shapes their knowledge, preferences, choices and behaviors. The Pre-FPQ is an innovative tool to measure preschool children's knowledge of and preference for food and physical activity. The questionnaire offers the advantage of being presented in a well-received modality for preschool children as well as being easy and inexpensive to administer. This new tool is likely to be useful for the assessment of the effectiveness of healthy lifestyle programs implemented in the childcare setting. Future work is needed to refine and improve measures of physical activity preference in preschool children.

  7. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based paint... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Lead-based paint activities...

  8. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based paint... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Lead-based paint activities...

  9. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based paint... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Lead-based paint activities...

  10. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based paint... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Lead-based paint activities...

  11. 40 CFR 745.233 - Lead-based paint activities requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) TOXIC SUBSTANCES CONTROL ACT LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Lead-Based Paint Activities § 745.233 Lead-based paint activities requirements. Lead-based paint... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Lead-based paint activities...

  12. Patient activation, knowledge, and health literacy association with self-management behaviors in persons with heart failure.

    PubMed

    Jacobson, Ann F; Sumodi, Veronica; Albert, Nancy M; Butler, Robert S; DeJohn, Lori; Walker, Donna; Dion, Kelly; Tai, Hua-Li Lin; Ross, Donna M

    2018-06-14

    More evidence is needed about factors that influence self-management behaviors in persons with heart failure. To test a correlational mediation model of the independent variables of health literacy, patient activation, and heart failure knowledge with heart failure self-management behaviors. The study used a prospective, cross-sectional, correlational design. Correlation and multiple regression were used to analyze associations among variables. Of 151 participants, 57% were male, and mean age was 68 years. Heart failure self-management behaviors was positively correlated with patient activation level (p = .0008), but not with health literacy or heart failure knowledge. Persons with heart failure may better manage their condition if sufficiently activated, regardless of their level of health literacy or knowledge of heart failure disease and management processes. Copyright © 2018 Elsevier Inc. All rights reserved.

  13. Knowledge, attitude and practice of physiotherapists towards promotion of physically active lifestyles in patient management.

    PubMed

    Aweto, Happiness A; Oligbo, Cynthia N; Fapojuwo, Oluseun A; Olawale, Olajide A

    2013-01-14

    Physiotherapists as primary health care practitioners are well placed in promoting physically active lifestyles, but their role and practice towards its promotion among patients in Nigeria has not been fully investigated. This study was therefore aimed at determining the knowledge, attitude and practice of Nigerian physiotherapists towards promotion of non-treatment physical activity among patients. Three hundred and eight practicing physiotherapists from various public and private hospitals in 14 states of Nigeria completed an adopted 20-item questionnaire, which collected information on physical activity promotion in physiotherapy practice. Respondents with good knowledge and attitude towards physical activity promotion in patient management were 196(63.6%) and 292(94.8%) respectively. Only 111 (36%) of the respondents counselled more than 10 patients in the past one month on the benefits of adopting a more physically active lifestyle. Chi-square analysis showed a significant association between low practice of physical activity promotion in patient management with inadequate consultation time (ℵ2=3.36, p=0.043), years of working experience of physiotherapists (ℵ2=11.37, p=0.023) and relative physical activity levels of physiotherapists (ℵ2=11.82, p=0.037). The need for Physical activity recommendation guideline was supported by 287 (97%) respondents. Nigerian physiotherapists have good knowledge and attitude towards promotion of physically active lifestyle in their patients but do not counsel many of them, due to insufficient consultation time. Integrating brief counselling into usual treatment sessions is perceived as the most feasible form of physical activity promotion in patient management.

  14. Daily Parental Knowledge of Youth Activities Is Linked to Youth Physical Symptoms and HPA functioning

    PubMed Central

    Lippold, Melissa A.; Davis, Kelly D.; McHale, Susan M.; Almeida, David M.

    2015-01-01

    Considerable evidence documents linkages between parental knowledge of youth activities and youth risky behavior. We extended this research to determine whether parental knowledge was associated with youth physical health, including reports of physical symptoms (e.g., headaches, stomachaches) and a biomarker of hypothalamic pituitary adrenocortical (HPA) axis functioning (i.e., salivary cortisol levels). Participants were children of employees in the Information Technology division of a Fortune 500 company (N = 132, Mean Age Youth = 13.39 years, 55% female) who participated in a daily diary study. Data were collected via telephone calls on eight consecutive evenings. On four study days, cortisol samples were collected at 4 time points (waking, 30 min after waking, before dinner, bedtime). Multi-level models revealed that, at the between-person level, youth whose parents had higher average knowledge about their activities, exhibited lower bedtime cortisol levels. Furthermore, at the within-person level, on days when parents displayed more knowledge than usual (relative to their own eight-day average), youth had lower before-dinner cortisol than usual. Linkages between average parental knowledge and physical health symptoms were moderated by youth age: Younger but not older adolescents whose parents were more knowledgeable had fewer physical health symptoms, on average. A next step is to identify the processes that underlie these associations. PMID:26751757

  15. Knowledge Activation versus Sentence Mapping When Representing Fictional Characters' Emotional States.

    ERIC Educational Resources Information Center

    Gernsbacher, Morton Ann; Robertson, Rachel R. W.

    1992-01-01

    In a study of knowledge activation and sentence mapping, subjects read stories that described concrete actions, and then the content of the stories was manipulated (i.e. stories were written that implied different emotional states). It is suggested that the more emotionally evoking situations one encounters the more memory traces are stored and…

  16. Knowledge management for efficient quantitative analyses during regulatory reviews.

    PubMed

    Krudys, Kevin; Li, Fang; Florian, Jeffry; Tornoe, Christoffer; Chen, Ying; Bhattaram, Atul; Jadhav, Pravin; Neal, Lauren; Wang, Yaning; Gobburu, Joga; Lee, Peter I D

    2011-11-01

    Knowledge management comprises the strategies and methods employed to generate and leverage knowledge within an organization. This report outlines the activities within the Division of Pharmacometrics at the US FDA to effectively manage knowledge with the ultimate goal of improving drug development and advancing public health. The infrastructure required for pharmacometric knowledge management includes provisions for data standards, queryable databases, libraries of modeling tools, archiving of analysis results and reporting templates for effective communication. Two examples of knowledge management systems developed within the Division of Pharmacometrics are used to illustrate these principles. The benefits of sound knowledge management include increased productivity, allowing reviewers to focus on research questions spanning new drug applications, such as improved trial design and biomarker development. The future of knowledge management depends on the collaboration between the FDA and industry to implement data and model standards to enhance sharing and dissemination of knowledge.

  17. Activity Theory as a Lens to Understand How Facebook Develops Knowledge Application Skills

    ERIC Educational Resources Information Center

    Bagarukayo, Emily; Ssentamu, Proscovia; Mayisela, Tabisa; Brown, Cheryl

    2016-01-01

    Uganda's higher education system has generally been criticized for concentrating on theory leading to a mismatch between training received and practical skills required by employers. Studies have documented the inability of graduates from some programmes at Makerere University in applying knowledge in the work environment. This could partly be…

  18. Hemispheric asymmetry in event knowledge activation during incremental language comprehension: A visual half-field ERP study.

    PubMed

    Metusalem, Ross; Kutas, Marta; Urbach, Thomas P; Elman, Jeffrey L

    2016-04-01

    During incremental language comprehension, the brain activates knowledge of described events, including knowledge elements that constitute semantic anomalies in their linguistic context. The present study investigates hemispheric asymmetries in this process, with the aim of advancing our understanding of the neural basis and functional properties of event knowledge activation during incremental comprehension. In a visual half-field event-related brain potential (ERP) experiment, participants read brief discourses in which the third sentence contained a word that was either highly expected, semantically anomalous but related to the described event (Event-Related), or semantically anomalous but unrelated to the described event (Event-Unrelated). For both visual fields of target word presentation, semantically anomalous words elicited N400 ERP components of greater amplitude than did expected words. Crucially, Event-Related anomalous words elicited a reduced N400 relative to Event-Unrelated anomalous words only with left visual field/right hemisphere presentation. This result suggests that right hemisphere processes are critical to the activation of event knowledge elements that violate the linguistic context, and in doing so informs existing theories of hemispheric asymmetries in semantic processing during language comprehension. Additionally, this finding coincides with past research suggesting a crucial role for the right hemisphere in elaborative inference generation, raises interesting questions regarding hemispheric coordination in generating event-specific linguistic expectancies, and more generally highlights the possibility of functional dissociation of event knowledge activation for the generation of elaborative inferences and for linguistic expectancies. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. Hemispheric Asymmetry in Event Knowledge Activation During Incremental Language Comprehension: A Visual Half-Field ERP Study

    PubMed Central

    Metusalem, Ross; Kutas, Marta; Urbach, Thomas P.; Elman, Jeffrey L.

    2016-01-01

    During incremental language comprehension, the brain activates knowledge of described events, including knowledge elements that constitute semantic anomalies in their linguistic context. The present study investigates hemispheric asymmetries in this process, with the aim of advancing our understanding of the neural basis and functional properties of event knowledge activation during incremental comprehension. In a visual half-field event-related brain potential (ERP) experiment, participants read brief discourses in which the third sentence contained a word that was either highly expected, semantically anomalous but related to the described event, or semantically anomalous but unrelated to the described event. For both visual fields of target word presentation, semantically anomalous words elicited N400 ERP components of greater amplitude than did expected words. Crucially, event-related anomalous words elicited a reduced N400 relative to event-unrelated anomalous words only with left visual field/right hemisphere presentation. This result suggests that right hemisphere processes are critical to the activation of event knowledge elements that violate the linguistic context, and in doing so informs existing theories of hemispheric asymmetries in semantic processing during language comprehension. Additionally, this finding coincides with past research suggesting a crucial role for the right hemisphere in elaborative inference generation, raises interesting questions regarding hemispheric coordination in generating event-specific linguistic expectancies, and more generally highlights the possibility of functional dissociation between event knowledge activation for the generation of elaborative inferences and for linguistic expectancies. PMID:26878980

  20. Local people's knowledge with regard to land use activities in southwest Madagascar - Conceptual insights for sustainable land management.

    PubMed

    Fritz-Vietta, Nadine V M; Tahirindraza, H Stone; Stoll-Kleemann, Susanne

    2017-09-01

    Environmental conditions in the Mahafaly Plateau region in southwest Madagascar are harsh, with a long dry season and a short rainy season. The local people's land use capabilities and skills are adapted to these conditions. Nevertheless, they are currently confronted by drastic climatic changes, including longer dry seasons, which have resulted in food and water scarcities. It is therefore essential to ensure sustainable land management in the region. At present, the main land use activities are agriculture, livestock farming, natural resource collection including timber and non-timber forest products, and the practice of local customs. Land use activities have always resulted in land conversion, yet over time this ecological transformation also leads to the accumulation of knowledge. The aim of the present article is therefore twofold. First, it aims to examine local people's knowledge with regard to land use activities and the transmission of this knowledge from one generation to the next; second, it considers the extent to which local people's knowledge may contribute to the development of sustainable land management. Our research is based on more than 80 qualitative interviews with local inhabitants of the Mahafaly Plateau region. Our analysis of local people's knowledge identifies four categories: ecological knowledge, knowledge related to natural resource usage, knowledge of names, and the interconnection between knowledge and belief. Furthermore, these knowledge categories provide conceptual insights for sustainable land management. Along with the long-term persistence of natural resources and their functions and the satisfaction of basic needs through resource usage, both the recognition of mental images as a regulating mechanism and the maintenance of the relation between the natural and the supernatural world have a role to play in sustainable land management in the study area. Local knowledge transmission processes serve to foster ongoing learning and

  1. Designing the RiverCare knowledge base and web-collaborative platform to exchange knowledge in river management

    NASA Astrophysics Data System (ADS)

    Cortes Arevalo, Juliette; den Haan, Robert-Jan; van der Voort, Mascha; Hulscher, Suzanne

    2016-04-01

    Effective communication strategies are necessary between different scientific disciplines, practitioners and non-experts for a shared understanding and better implementation of river management measures. In that context, the RiverCare program aims to get a better understanding of riverine measures that are being implemented towards self-sustaining multifunctional rivers in the Netherlands. During the RiverCare program, user committees are organized between the researchers and practitioners to discuss the aim and value of RiverCare outputs, related assumptions and uncertainties behind scientific results. Beyond the RiverCare program end, knowledge about river interventions, integrated effects, management and self-sustaining applications will be available to experts and non-experts by means of River Care communication tools: A web-collaborative platform and a serious gaming environment. As part of the communication project of RiverCare, we are designing the RiverCare web-collaborative platform and the knowledge-base behind that platform. We aim at promoting collaborative efforts and knowledge exchange in river management. However, knowledge exchange does not magically happen. Consultation and discussion of RiverCare outputs as well as elicitation of perspectives and preferences from different actors about the effects of riverine measures has to be facilitated. During the RiverCare research activities, the platform will support the user committees or collaborative sessions that are regularly held with the organizations directly benefiting from our research, at project level or in study areas. The design process of the collaborative platform follows an user centred approach to identify user requirements, co-create a conceptual design and iterative develop and evaluate prototypes of the platform. The envisioned web-collaborative platform opens with an explanation and visualisation of the RiverCare outputs that are available in the knowledge base. Collaborative sessions

  2. Challenges of Knowledge Management and Creation in Communities of Practice Organisations of Deaf and Non-Deaf Members: Requirements for a Web Platform

    ERIC Educational Resources Information Center

    de Freitas Guilhermino Trindade, Daniela; Guimaraes, Cayley; Antunes, Diego Roberto; Garcia, Laura Sanchez; Lopes da Silva, Rafaella Aline; Fernandes, Sueli

    2012-01-01

    This study analysed the role of knowledge management (KM) tools used to cultivate a community of practice (CP) in its knowledge creation (KC), transfer, learning processes. The goal of such observations was to determine requirements that KM tools should address for the specific CP formed by Deaf and non-Deaf members of the CP. The CP studied is a…

  3. Examining the Knowledge and Capacity of Elementary Teachers to Implement Classroom Physical Activity Breaks

    ERIC Educational Resources Information Center

    Dinkel, Danae M.; Lee, Jung-Min; Schaffer, Connie

    2016-01-01

    This study examined teachers' zone of proximal development for classroom physical activity breaks by assessing teachers' knowledge and capacity for implementing classroom physical activity breaks. Five school districts of various sizes (n = 346 teachers) took part in a short online survey. Descriptive statistics were calculated and chi-square…

  4. Activation-specific metabolic requirements for NK cell IFN-γ production1

    PubMed Central

    Keppel, Molly P.; Topcagic, Nermina; Mah, Annelise Y.; Vogel, Tiphanie P.; Cooper, Megan A.

    2014-01-01

    There has been increasing recognition of the importance of cellular metabolism and metabolic substrates for the function and differentiation of immune cells. Here, for the first time, we investigate the metabolic requirements for production of IFN-γ by freshly isolated NK cells. Primary murine NK cells mainly utilize mitochondrial oxidative phosphorylation at rest and with short-term activation. Remarkably, we discovered significant differences in the metabolic requirements of murine NK cell IFN-γ production depending upon the activation signal. Stimulation of NK cell IFN-γ production was independent of glycolysis or mitochondrial oxidative phosphorylation when cells were activated with IL-12+IL-18. By contrast, stimulation via activating NK receptors required glucose-driven oxidative phosphorylation. Prolonged treatment with high-dose, but not low dose, IL-15 eliminated the metabolic requirement for receptor stimulation. In summary, this study demonstrates that metabolism provides an essential second signal for induction of IFN-γ production by activating NK cell receptors that can be reversed with prolonged high-dose IL-15 treatment. PMID:25595780

  5. High-Fidelity Simulation in Nursing Practice: The Impact on Nurses' Knowledge Acquisition, Satisfaction, and Self-Confidence

    ERIC Educational Resources Information Center

    Square, Nicole Decuir

    2012-01-01

    Nurses require ongoing opportunities to expand knowledge and skills; this expansion of knowledge and skills is one aspect of continued competence. One method that may be used to maintain and refine knowledge and skills is participation in continuing education activities. However, there has been little inquiry into creative strategies used in…

  6. Knowledge of physical activity recommendations in adults employed in England: associations with individual and workplace-related predictors.

    PubMed

    Knox, Emily C L; Musson, Hayley; Adams, Emma J

    2015-05-23

    Physical activity guidelines state that adults should engage in at least 150 min of moderate to vigorous physical activity (MVPA) per week to benefit health. A high proportion of adults in England fail to reach this target. Accurate knowledge of MVPA guidelines could influence the amount and quality of MVPA engaged in by adults. This study aimed to determine knowledge of the MVPA guideline within a large sample of working adults in England and identify individual and workplace-related predictors of knowledge. 10,992 adults completed an online survey which included questions on demographics, knowledge of the MVPA guideline and workplace predictors for physical activity. Multinomial logistic regression identified predictors of underestimating, overestimating or not knowing the MVPA guideline relative to accurately reporting the guideline for males and females separately. Respondents were 37% male, 95% White, 63% with a degree or higher, and had a mean age of 38.9 ± 11 years. The MVPA guideline was accurately reported by 15% of adults while 13.8% overestimated, 8.9% underestimated and 62.3% failed to provide any estimate of the guideline. Low education predicted underestimation (females: OR = 0.36, 95% CI 0.17, 0.80) and not knowing (males: OR = 0.37, 95% CI 0.14, 0.96; females: OR = 0.36, 95% CI 0.19, 0.69). Ethnicity was a significant predictor for females only (OR 3.55, 95% CI 1.46, 8.63; OR 4.03, 95% CI 1.58, 10.27; OR 3.73, 95% CI 1.67, 8.33). Employer support for physical activity was a significant predictor of accurate knowledge of the MVPA guideline for both males (underestimation: OR = 0.63, 95% CI 0.40, 1.00; 'don't know': OR = 0.71, 95% CI 0.51, 1.00) and females (overestimation: OR = 0.72, 95% CI 0.53, 0.97; underestimation: OR = 0.66, 95% CI 0.47, 0.92; 'don't know': OR = 0.60, 95% CI 0.47, 0.76). Knowledge of the MVPA guideline within working adults in England is low. Employers should play a role in using targeted

  7. The Nuclear Energy Knowledge and Validation Center Summary of Activities Conducted in FY16

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gougar, Hans David

    The Nuclear Energy Knowledge and Validation Center (NEKVaC) is a new initiative by the Department of Energy (DOE) and Idaho National Laboratory (INL) to coordinate and focus the resources and expertise that exist with the DOE toward solving issues in modern nuclear code validation and knowledge management. In time, code owners, users, and developers will view the NEKVaC as a partner and essential resource for acquiring the best practices and latest techniques for validating codes, providing guidance in planning and executing experiments, facilitating access to and maximizing the usefulness of existing data, and preserving knowledge for continual use by nuclearmore » professionals and organizations for their own validation needs. The scope of the NEKVaC covers many interrelated activities that will need to be cultivated carefully in the near term and managed properly once the NEKVaC is fully functional. Three areas comprise the principal mission: (1) identify and prioritize projects that extend the field of validation science and its application to modern codes, (2) develop and disseminate best practices and guidelines for high-fidelity multiphysics/multiscale analysis code development and associated experiment design, and (3) define protocols for data acquisition and knowledge preservation and provide a portal for access to databases currently scattered among numerous organizations. These mission areas, while each having a unique focus, are interdependent and complementary. Likewise, all activities supported by the NEKVaC, both near term and long term, must possess elements supporting all three areas. This cross cutting nature is essential to ensuring that activities and supporting personnel do not become “stove piped” (i.e., focused a specific function that the activity itself becomes the objective rather than achieving the larger vision). This report begins with a description of the mission areas; specifically, the role played by each major committee and

  8. Parental knowledge of adolescent activities: links with parental attachment style and adolescent substance use.

    PubMed

    Jones, Jason D; Ehrlich, Katherine B; Lejuez, C W; Cassidy, Jude

    2015-04-01

    Parents' knowledge of their adolescents' whereabouts and activities is a robust predictor of adolescent risk behavior, including the use of drugs and alcohol. Surprisingly few studies have attempted to identify parental characteristics that are associated with the degree of parental knowledge. The present study is the first to examine how parental attachment style relates to mother, father, and adolescent reports of parental knowledge. Further, we used structural equation modeling to test the associations among parents' attachment styles, reports of parental knowledge, and adolescents' alcohol and marijuana use. Participants included 203 adolescents (M age = 14.02, SD = .91) living in 2-parent households and their parent(s). As predicted, mothers' and fathers' insecure attachment styles were negatively associated with self-reported and adolescent-reported parental knowledge, and all 3 reports of parental knowledge were negatively related to adolescent substance use. Mothers' and fathers' attachment styles were unrelated to adolescent substance use. However, evidence emerged for indirect effects of parental attachment style on adolescent substance use through reports of parental knowledge. Implications for prevention efforts and the importance of multiple reporters within the family are discussed. (c) 2015 APA, all rights reserved).

  9. Parental Knowledge of Adolescent Activities: Links with Parental Attachment Style and Adolescent Substance Use

    PubMed Central

    Jones, Jason D.; Ehrlich, Katherine B.; Lejuez, C. W.; Cassidy, Jude

    2015-01-01

    Parents’ knowledge of their adolescents’ whereabouts and activities is a robust predictor of adolescent risk behavior, including the use of drugs and alcohol. Surprisingly few studies have attempted to identify parental characteristics that are associated with the degree of parental knowledge. The present study is the first to examine how parental attachment style relates to mother, father, and adolescent reports of parental knowledge. Further, we used structural equation modeling to test the associations among parents’ attachment styles, reports of parental knowledge, and adolescents’ alcohol and marijuana use. Participants included 203 adolescents (mean age = 14.02, SD = .91) living in two-parent households and their parent(s). As predicted, mothers’ and fathers’ insecure attachment styles were negatively associated with self-reported and adolescent-reported parental knowledge, and all three reports of parental knowledge were negatively related to adolescent substance use. Mothers’ and fathers’ attachment styles were unrelated to adolescent substance use. However, evidence emerged for indirect effects of parental attachment style on adolescent substance use through reports of parental knowledge. Implications for prevention efforts and the importance of multiple reporters within the family are discussed. PMID:25730406

  10. 10 CFR 60.46 - Particular activities requiring license amendment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Particular activities requiring license amendment. 60.46 Section 60.46 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses License Issuance and Amendment § 60.46 Particular activities...

  11. 10 CFR 60.46 - Particular activities requiring license amendment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Particular activities requiring license amendment. 60.46 Section 60.46 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Licenses License Issuance and Amendment § 60.46 Particular activities...

  12. The Extension-Reduction Strategy: Activating Prior Knowledge

    ERIC Educational Resources Information Center

    Sloyer, Cliff W.

    2004-01-01

    A mathematical problem is solved using the extension-reduction or build it up-tear it down tactic. This technique is implemented in reviving students' earlier knowledge to enable them to apply this knowledge to solving new problems.

  13. Current Situation and Analysis of Geography Teachers' Active Learning Knowledge and Usage in Turkey

    ERIC Educational Resources Information Center

    Tuna, Fikret

    2012-01-01

    In parallel to the developments in the approach to education, the secondary education geography curriculum in Turkey was renewed in 2005. This new programme encourages the use of active learning methods and techniques in the classroom by adopting the idea that students should construct and interpret knowledge by actively participating in the…

  14. Correlation set analysis: detecting active regulators in disease populations using prior causal knowledge

    PubMed Central

    2012-01-01

    Background Identification of active causal regulators is a crucial problem in understanding mechanism of diseases or finding drug targets. Methods that infer causal regulators directly from primary data have been proposed and successfully validated in some cases. These methods necessarily require very large sample sizes or a mix of different data types. Recent studies have shown that prior biological knowledge can successfully boost a method's ability to find regulators. Results We present a simple data-driven method, Correlation Set Analysis (CSA), for comprehensively detecting active regulators in disease populations by integrating co-expression analysis and a specific type of literature-derived causal relationships. Instead of investigating the co-expression level between regulators and their regulatees, we focus on coherence of regulatees of a regulator. Using simulated datasets we show that our method performs very well at recovering even weak regulatory relationships with a low false discovery rate. Using three separate real biological datasets we were able to recover well known and as yet undescribed, active regulators for each disease population. The results are represented as a rank-ordered list of regulators, and reveals both single and higher-order regulatory relationships. Conclusions CSA is an intuitive data-driven way of selecting directed perturbation experiments that are relevant to a disease population of interest and represent a starting point for further investigation. Our findings demonstrate that combining co-expression analysis on regulatee sets with a literature-derived network can successfully identify causal regulators and help develop possible hypothesis to explain disease progression. PMID:22443377

  15. Knowledge and Its Enemies

    ERIC Educational Resources Information Center

    Kruk, Miroslav

    2007-01-01

    As libraries are the physical manifestations of knowledge, some refection about the concept of knowledge would not be unjustified. In modern societies, knowledge plays such a central role that it requires some effort and imagination to understand on what grounds knowledge could be rejected. Karl Popper wrote about the open society and its enemies.…

  16. Knowledge and Policy: Research and Knowledge Transfer

    ERIC Educational Resources Information Center

    Ozga, Jenny

    2007-01-01

    Knowledge transfer (KT) is the emergent "third sector" of higher education activity--alongside research and teaching. Its commercialization origins are evidenced in its concerns to extract maximum value from research, and in the policy push to make research-based knowledge trapped in disciplinary silos more responsive to the growing…

  17. Comparison of active-learning strategies for motivational interviewing skills, knowledge, and confidence in first-year pharmacy students.

    PubMed

    Lupu, Ana M; Stewart, Autumn L; O'Neil, Christine

    2012-03-12

    To compare 3 strategies for pharmacy student learning of motivational interviewing skills, knowledge of motivational interviewing principles, and confidence in and attitudes toward their application. Following a motivational interviewing lecture, first-year students were randomized to perform practice activities (written dialogue, peer role-play, or mock-patient counseling activities). Motivational interviewing skills, knowledge, confidence, and attitudes were measured. All students demonstrated improvement in skills, knowledge, and confidence. Students in the mock-patient counseling group demonstrated significantly better motivational interviewing skills during practice and trended toward higher scores on the summative evaluation. They also demonstrated a significant improvement in knowledge compared with that of the written dialogue group during practice. Feedback at the end was generally positive, with students expressing recognition for the value of motivational interviewing. Students demonstrated their best performance of motivational interviewing during assessments using interactions with mock or standardized patients.

  18. [Correlation between knowledge about the consequences of obesity and physical activity levels among university students].

    PubMed

    Ocampo-Mascaró, Javier; Silva-Salazar, Vera; da Costa-Bullón, A Daniel

    2015-12-02

    Obesity is a growing public health issue. One of the main strategies to prevent it is physical activity. To determine if a correlation exists between awareness of the consequences of obesity and physical activity level. A cross-sectional study performed on a group of 215 students was conducted in 2013 and 2014. Non-health related program students were selected by convenience sampling at a university in Lima, Peru. Their physical activity level was measured using the International Physical Activity Questionnaire (IPAQ), and knowledge about the consequences of obesity was assessed using the Obesity Risk Knowledge-10 scale (ORK-10). Each student was also asked to record the source where they obtained whatever information they knew about the topic. The median age of the participants was 20 (interquartile range of 4; 22-18), and 63% of the participants were female. According to the IPAQ, 53.9% of the participants recorded high levels of physical activity, 35.4% recorded moderate levels, and 10.7%, recorded low levels. While a low correlation between the ORK-10 score and the amount of METs/minute/week spent was found (rs=0.06), it was not significant (p=0.38). We found that people who were informed by the media or by healthcare personnel achieved higher scores on the ORK-10 scale than those who used other sources of information (p<0,05). There is a very low correlation between the knowledge about the consequences of obesity and a person’s physical activity level. A multidisciplinary approach that includes all determinants of physical activity is necessary in order to attain changes in people’s behavior.

  19. Co-producing active lifestyles as whole-system-approach: theory, intervention and knowledge-to-action implications.

    PubMed

    Rütten, Alfred; Frahsa, Annika; Abel, Thomas; Bergmann, Matthias; de Leeuw, Evelyne; Hunter, David; Jansen, Maria; King, Abby; Potvin, Louise

    2017-09-08

    Population health interventions tend to lack links to the emerging discourse on interactive knowledge production and exchange. This situation may limit both a better understanding of mechanisms that impact health lifestyles and the development of strategies for population level change. This paper introduces an integrated approach based on structure-agency theory in the context of 'social practice'. It investigates the mechanisms of co-production of active lifestyles by population groups, professionals, policymakers and researchers. It combines a whole system approach with an interactive knowledge-to-action strategy for developing and implementing active lifestyle interventions. A system model is outlined to describe and explain how social practices of selected groups co-produce active lifestyles. Four intervention models for promoting the co-production of active lifestyles through an interactive-knowledge-to-action approach are discussed. Examples from case studies of the German research network Capital4Health are used to illustrate, how intervention models might be operationalized in a real-world intervention. Five subprojects develop, implement and evaluate interventions across the life-course. Although subprojects differ with regard to settings and population groups involved, they all focus on the four key components of the system model. The paper contributes new strategies to address the intervention research challenge of sustainable change of inactive lifestyles. The interactive approach presented allows consideration of the specificities of settings and scientific contexts for manifold purposes. Further research remains needed on what a co-produced knowledge-to-action agenda would look like and what impact it might have for whole system change. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  20. 10 CFR 60.7 - License not required for certain preliminary activities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false License not required for certain preliminary activities. 60.7 Section 60.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE... activities. The requirement for a license set forth in § 60.3(a) of this part is not applicable to the extent...

  1. Effect of Personalized System of Instruction on Health-Related Fitness Knowledge and Class Time Physical Activity

    ERIC Educational Resources Information Center

    Prewitt, Steven L.; Hannon, James C.; Colquitt, Gavin; Brusseau, Timothy A.; Newton, Maria; Shaw, Janet

    2015-01-01

    In previous studies, researchers have identified a general low level of health-related fitness (HRF) knowledge among secondary students that can effect levels of physical activity (PA). An instructional strategy that may increase HRF knowledge without decreasing PA is the personalized system of instruction (PSI). Two classes from a private urban…

  2. 43 CFR 5.4 - When is a permit required for news-gathering activities?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false When is a permit required for news... Wildlife Service § 5.4 When is a permit required for news-gathering activities? (a) Permit requirements. News-gathering activities involving filming, videography, or still photography do not require a permit...

  3. 43 CFR 5.4 - When is a permit required for news-gathering activities?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false When is a permit required for news... Wildlife Service § 5.4 When is a permit required for news-gathering activities? (a) Permit requirements. News-gathering activities involving filming, videography, or still photography do not require a permit...

  4. [Artificial intelligence--the knowledge base applied to nephrology].

    PubMed

    Sancipriano, G P

    2005-01-01

    The idea that efficacy efficiency, and quality in medicine could not be reached without sorting the huge knowledge of medical and nursing science is very common. Engineers and computer scientists have developed medical software with great prospects for success, but currently these software applications are not so useful in clinical practice. The medical doctor and the trained nurse live the 'information age' in many daily activities, but the main benefits are not so widespread in working activities. Artificial intelligence and, particularly, export systems charm health staff because of their potential. The first part of this paper summarizes the characteristics of 'weak artificial intelligence' and of expert systems important in clinical practice. The second part discusses medical doctors' requirements and the current nephrologic knowledge bases available for artificial intelligence development.

  5. Writing Science and Objectification: Selecting, Organizing, and Decontextualing Knowledge

    ERIC Educational Resources Information Center

    Wright, Laura J.

    2008-01-01

    This analysis focuses on two writing activities required by a middle school science curriculum unit to demonstrate how particular forms of writing guide students to frame their knowledge in important ways. Following the completion of charts and "Think and Write" questions related to a single scientific phenomenon, I trace how students identify the…

  6. Knowledge at Work.

    ERIC Educational Resources Information Center

    Scribner, Sylvia

    1985-01-01

    Activity theory posits that culturally organized actions guide the acquisition and organization of knowledge. This theory was applied to the organization of knowledge within a large milk processing plant. The dairy was found to be organized by social knowledge, yet individuals creatively synthesized several domains of knowledge to organize their…

  7. Improving Oncology Nurses' Knowledge About Nutrition and Physical Activity for Cancer Survivors.

    PubMed

    van Veen, Merel R; Hoedjes, Meeke; Versteegen, Joline J; van de Meulengraaf-Wilhelm, Nienke; Kampman, Ellen; Beijer, Sandra

    2017-07-01

    To assess what percentage of oncology nurses perceived themselves as having insufficient knowledge to provide advice on nutrition and/or physical activity (PA), which characteristics were associated with nurses' perception, and whether the content and information sources differed among those nurses.
. A cross-sectional study.
. A web-based survey among oncology nurses in the Netherlands.
. 355 oncology nurses provided advice on nutrition; of these, 327 provided advice on PA.
. From May to July 2013, oncology nurses were invited to complete an online questionnaire. Pearson's chi-squared tests and uni- and multivariate logistic regression analyses were conducted.
. Oncology nurses' perception of having sufficient or insufficient knowledge to be able to provide advice on nutrition and PA, the content of the advice, and the information sources on which the advice was based.
. 43% of oncology nurses perceived themselves as having insufficient knowledge to provide advice on nutrition, and 46% perceived insufficient knowledge to provide advice on PA. Factors associated with perceiving insufficient knowledge on nutrition were being aged younger, having lower education, and providing counseling during treatment only. Those nurses were more likely to suggest taking oral nutritional supplements or visiting a dietitian and were less likely to provide information on fluid intake. Nurses perceiving insufficient knowledge about PA used oncology guidelines less often.
. Almost half of the oncology nurses providing advice on nutrition and PA perceived themselves as having insufficient knowledge to be able to provide such advice. In particular, younger oncology nurses and oncology nurses with an intermediate vocational education may benefit most from education about these topics. 
. Educational training for oncology nurses should include nutrition and PA. Oncology nurses should collaborate with dietitians to discuss what information should be provided to patients by

  8. Formalization of the engineering science discipline - knowledge engineering

    NASA Astrophysics Data System (ADS)

    Peng, Xiao

    Knowledge is the most precious ingredient facilitating aerospace engineering research and product development activities. Currently, the most common knowledge retention methods are paper-based documents, such as reports, books and journals. However, those media have innate weaknesses. For example, four generations of flying wing aircraft (Horten, Northrop XB-35/YB-49, Boeing BWB and many others) were mostly developed in isolation. The subsequent engineers were not aware of the previous developments, because these projects were documented such which prevented the next generation of engineers to benefit from the previous lessons learned. In this manner, inefficient knowledge retention methods have become a primary obstacle for knowledge transfer from the experienced to the next generation of engineers. In addition, the quality of knowledge itself is a vital criterion; thus, an accurate measure of the quality of 'knowledge' is required. Although qualitative knowledge evaluation criteria have been researched in other disciplines, such as the AAA criterion by Ernest Sosa stemming from the field of philosophy, a quantitative knowledge evaluation criterion needs to be developed which is capable to numerically determine the qualities of knowledge for aerospace engineering research and product development activities. To provide engineers with a high-quality knowledge management tool, the engineering science discipline Knowledge Engineering has been formalized to systematically address knowledge retention issues. This research undertaking formalizes Knowledge Engineering as follows: 1. Categorize knowledge according to its formats and representations for the first time, which serves as the foundation for the subsequent knowledge management function development. 2. Develop an efficiency evaluation criterion for knowledge management by analyzing the characteristics of both knowledge and the parties involved in the knowledge management processes. 3. Propose and develop an

  9. Time required for motor activity in lucid dreams.

    PubMed

    Erlacher, Daniel; Schredl, Michael

    2004-12-01

    The present study investigated the relationship between the time required for specific tasks (counting and performing squats) in lucid dreams and in the waking state. Five proficient lucid dreamers (26-34 yr. old, M=29.8, SD=3.0; one woman and four men) participated. Analysis showed that the time needed for counting in a lucid dream is comparable to the time needed for counting in wakefulness, but motor activities required more time in lucid dreams than in the waking state.

  10. Knowledge, perceived skills and activities of nursing staff to support oral home care among older domiciliary care clients.

    PubMed

    Salmi, Riikka; Tolvanen, Mimmi; Suhonen, Riitta; Lahti, Satu; Närhi, Timo

    2018-04-25

    Increasing number of older adults lives in their own homes, but needs help in many daily routines. Domiciliary care nursing staff (DCNS) is often needed to support oral home care. However, information of nursing staff's knowledge, skills and activity in this task is sparse. The study aimed to assess DCNS knowledge, perceived skills and activities to support oral home care of older domiciliary care clients. The study was conducted among DCNS in one of the largest cities in Finland. All DCNS members (n = 465) received a questionnaire with 14 multiple choice and open questions regarding the perceived skills, knowledge and activities of oral health guidance of older domiciliary care clients. In total, 115 (25%) DCNS members returned the questionnaires. Frequencies, percentages, means and standard deviations were used to describe the samples and study variables. DCNS was categorised according to age and working years for group comparisons, which were assessed with chi-squared test. Knowledge concerning oral health was mostly on a high level. Around 50% of DCNS considered their knowledge regarding dental prosthesis hygiene as sufficient. Of the DCNS, 67% informed that they had received education on oral health care. However, over 50% of the DCNS had a need for further education in issues related to oral home care. DCNS were active in supporting most oral and prosthesis hygiene means, yet less in guidance concerning toothbrushing. Activity to support cleaning the interdental spaces was the weakest, in which only 12% of the respondents considered having average or excellent skills. Younger DCNS had better knowledge on oral home care due to recent education, but older staff members were more skilful in performing oral hygiene measures. There is a need for structured instructions and training on oral home care for DCNS. Oral home care should be taken into account more often and regularly. © 2018 Nordic College of Caring Science.

  11. Risk of error estimated from Palestine pharmacists' knowledge and certainty on the adverse effects and contraindications of active pharmaceutical ingredients and excipients.

    PubMed

    Shawahna, Ramzi; Al-Rjoub, Mohammed; Al-Horoub, Mohammed M; Al-Hroub, Wasif; Al-Rjoub, Bisan; Al-Nabi, Bashaaer Abd

    2016-01-01

    This study aimed to investigate community pharmacists' knowledge and certainty of adverse effects and contraindications of pharmaceutical products to estimate the risk of error. Factors influencing their knowledge and certainty were also investigated. The knowledge of community pharmacists was assessed in a cross-sectional design using a multiple-choice questions test on the adverse effects and contraindications of active pharmaceutical ingredients and excipients from May 2014 to March 2015. Self-rated certainty scores were also recorded for each question. Knowledge and certainty scores were combined to estimate the risk of error. Out of 315 subjects, 129 community pharmacists (41.0%) completed the 30 multiple-choice questions test on active ingredients and excipients. Knowledge on active ingredients was associated with the year of graduation and obtaining a licence to practice pharmacy. Knowledge on excipients was associated with the degree obtained. There was higher risk of error in items on excipients than those on ingredients (P<0.01). The knowledge of community pharmacists in Palestine was insufficient with high risk of errors. Knowledge of community pharmacists on the safety issues of active ingredients and excipients need to be improved.

  12. Learning to Teach: Pedagogical Content Knowledge in Adventure-Based Learning

    ERIC Educational Resources Information Center

    Sutherland, Sue; Stuhr, Paul T.; Ayvazo, Shiri

    2016-01-01

    Background: Many alternative curricular models exist in physical education to better meet the needs of students than the multi-activity team sports curriculum that dominates in the USA. These alternative curricular models typically require different content knowledge (CK) and pedagogical CK (PCK) to implement successfully. One of the complexities…

  13. Functional dissection of the alphavirus capsid protease: sequence requirements for activity.

    PubMed

    Thomas, Saijo; Rai, Jagdish; John, Lijo; Günther, Stephan; Drosten, Christian; Pützer, Brigitte M; Schaefer, Stephan

    2010-11-18

    The alphavirus capsid is multifunctional and plays a key role in the viral life cycle. The nucleocapsid domain is released by the self-cleavage activity of the serine protease domain within the capsid. All alphaviruses analyzed to date show this autocatalytic cleavage. Here we have analyzed the sequence requirements for the cleavage activity of Chikungunya virus capsid protease of genus alphavirus. Amongst alphaviruses, the C-terminal amino acid tryptophan (W261) is conserved and found to be important for the cleavage. Mutating tryptophan to alanine (W261A) completely inactivated the protease. Other amino acids near W261 were not having any effect on the activity of this protease. However, serine protease inhibitor AEBSF did not inhibit the activity. Through error-prone PCR we found that isoleucine 227 is important for the effective activity. The loss of activity was analyzed further by molecular modelling and comparison of WT and mutant structures. It was found that lysine introduced at position 227 is spatially very close to the catalytic triad and may disrupt electrostatic interactions in the catalytic site and thus inactivate the enzyme. We are also examining other sequence requirements for this protease activity. We analyzed various amino acid sequence requirements for the activity of ChikV capsid protease and found that amino acids outside the catalytic triads are important for the activity.

  14. Autophagy is required for the activation of NFκB.

    PubMed

    Criollo, Alfredo; Chereau, Fanny; Malik, Shoaib Ahmad; Niso-Santano, Mireia; Mariño, Guillermo; Galluzzi, Lorenzo; Maiuri, Maria Chiara; Baud, Véronique; Kroemer, Guido

    2012-01-01

    It is well-established that the activation of the inhibitor of NFκB (IκBα) kinase (IKK) complex is required for autophagy induction by multiple stimuli. Here, we show that in autophagy-competent mouse embryonic fibroblasts (MEFs), distinct autophagic triggers, including starvation, mTOR inhibition with rapamycin and p53 inhibition with cyclic pifithrin α lead to the activation of IKK, followed by the phosphorylation-dependent degradation of IκBα and nuclear translocation of NFκB. Remarkably, the NFκB signaling pathway was blocked in MEFs lacking either the essential autophagy genes Atg5 or Atg7. In addition, we found that tumor necrosis factor α (TNFα)-induced NFκB nuclear translocation is abolished in both Atg5- and Atg7-deficient MEFs. Similarly, the depletion of essential autophagy modulators, including ATG5, ATG7, Beclin 1 and VPS34, by RNA interference inhibited TNFα-driven NFκB activation in two human cancer cell lines. In conclusion, it appears that, at least in some instances, autophagy is required for NFκB activation, highlighting an intimate crosstalk between these two stress response signaling pathways.

  15. Knowledge management: An abstraction of knowledge base and database management systems

    NASA Technical Reports Server (NTRS)

    Riedesel, Joel D.

    1990-01-01

    Artificial intelligence application requirements demand powerful representation capabilities as well as efficiency for real-time domains. Many tools exist, the most prevalent being expert systems tools such as ART, KEE, OPS5, and CLIPS. Other tools just emerging from the research environment are truth maintenance systems for representing non-monotonic knowledge, constraint systems, object oriented programming, and qualitative reasoning. Unfortunately, as many knowledge engineers have experienced, simply applying a tool to an application requires a large amount of effort to bend the application to fit. Much work goes into supporting work to make the tool integrate effectively. A Knowledge Management Design System (KNOMAD), is described which is a collection of tools built in layers. The layered architecture provides two major benefits; the ability to flexibly apply only those tools that are necessary for an application, and the ability to keep overhead, and thus inefficiency, to a minimum. KNOMAD is designed to manage many knowledge bases in a distributed environment providing maximum flexibility and expressivity to the knowledge engineer while also providing support for efficiency.

  16. Advanced extravehicular activity systems requirements definition study

    NASA Technical Reports Server (NTRS)

    1988-01-01

    A study to define the requirements for advanced extravehicular activities (AEVA) was conducted. The purpose of the study was to develop an understanding of the EVA technology requirements and to map a pathway from existing or developing technologies to an AEVA system capable of supporting long-duration missions on the lunar surface. The parameters of an AEVA system which must sustain the crewmembers and permit productive work for long periods in the lunar environment were examined. A design reference mission (DRM) was formulated and used as a tool to develop and analyze the EVA systems technology aspects. Many operational and infrastructure design issues which have a significant influence on the EVA system are identified.

  17. A Sport Education Fitness Season's Impact on Students' Fitness Levels, Knowledge, and In-Class Physical Activity.

    PubMed

    Ward, Jeffery Kurt; Hastie, Peter A; Wadsworth, Danielle D; Foote, Shelby; Brock, Sheri J; Hollett, Nikki

    2017-09-01

    The purpose of this study was to determine the extent to which a sport education season of fitness could provide students with recommended levels of in-class moderate-to-vigorous physical activity (MVPA) while also increasing students' fitness knowledge and fitness achievement. One hundred and sixty-six 5th-grade students (76 boys, 90 girls) participated in a 20-lesson season called "CrossFit Challenge" during a 4-week period. The Progressive Aerobic Cardiovascular Endurance Run, push-ups, and curl-ups tests of the FITNESSGRAM® were used to assess fitness at pretest and posttest, while fitness knowledge was assessed through a validated, grade-appropriate test of health-related fitness knowledge (HRF). Physical activity was measured with Actigraph GT3X triaxial accelerometers. Results indicated a significant time effect for all fitness tests and the knowledge test. Across the entire season, the students spent an average of 54.5% of lesson time engaged in MVPA, irrespective of the type of lesson (instruction, free practice, or competition). The results suggest that configuring the key principles of sport education within a unit of fitness is an efficient model for providing students with the opportunity to improve fitness skill and HRF knowledge while attaining recommended levels of MVPA.

  18. Influence of prior knowledge of exercise duration on pacing strategies during game-based activities.

    PubMed

    Gabbett, Tim J; Walker, Ben; Walker, Shane

    2015-04-01

    To investigate the influence of prior knowledge of exercise duration on the pacing strategies employed during game-based activities. Twelve semiprofessional team-sport athletes (mean ± SD age 22.8 ± 2.1 y) participated in this study. Players performed 3 small-sided games in random order. In one condition (Control), players were informed that they would play the small-sided game for 12 min and then completed the 12-min game. In a 2nd condition (Deception), players were told that they would play the small-sided game for 6 minutes, but after completing the 6-min game, they were asked to complete another 6 min. In a 3rd condition (Unknown), players were not told how long they would be required to play the small-sided game, but the activity was terminated after 12 min. Movement was recorded using a GPS unit sampling at 10 Hz. Post hoc inspection of video footage was undertaken to count the number of possessions and the number and quality of disposals. Higher initial intensities were observed in the Deception (130.6 ± 3.3 m/min) and Unknown (129.3 ± 2.4 m/min) conditions than the Control condition (123.3 ± 3.4 m/min). Greater amounts of high-speed running occurred during the initial phases of the Deception condition, and more low-speed activity occurred during the Unknown condition. A moderately greater number of total skill involvements occurred in the Unknown condition than the Control condition. These findings suggest that during game-based activities, players alter their pacing strategy based on the anticipated endpoint of the exercise bout.

  19. Virtual Knowledge Brokering: Describing the Roles and Strategies Used by Knowledge Brokers in a Pediatric Physiotherapy Virtual Community of Practice.

    PubMed

    Hurtubise, Karen; Rivard, Lisa; Héguy, Léa; Berbari, Jade; Camden, Chantal

    2016-01-01

    Knowledge transfer in pediatric rehabilitation is challenging and requires active, multifaceted strategies. The use of knowledge brokers (KBs) is one such strategy noted to promote clinician behavior change. The success of using KBs to transfer knowledge relies on their ability to adapt to ever-changing clinical contexts. In addition, with the rapid growth of online platforms as knowledge transfer forums, KBs must become effective in virtual environments. Although the role of KBs has been studied in various clinical contexts, their emerging role in specific online environments designed to support evidence-based behavior change has not yet been described. Our objective is to describe the roles of, and strategies used by, four KBs involved in a virtual community of practice to guide and inform future online KB interventions. A descriptive design guided this study and a thematic content analysis process was used to analyze online KB postings. The Promoting Action on Research in Health Sciences knowledge transfer framework and online andragogical learning theories assisted in the coding. A thematic map was created illustrating the links between KBs' strategies and emerging roles in the virtual environment. We analyzed 95 posts and identified three roles: 1) context architect: promoting a respectful learning environment, 2) knowledge sharing promoter: building capacity, and 3) linkage creator: connecting research-to-practice. Strategies used by KBs reflected invitational, constructivism, and connectivism approaches, with roles and strategies changing over time. This study increases our understanding of the actions of KBs in virtual contexts to foster uptake of research evidence in pediatric physiotherapy. Our results provide valuable information about the knowledge and skills required by individuals to fulfill this role in virtual environments.

  20. So what exactly is nursing knowledge?

    PubMed

    Clarke, L

    2011-06-01

    This paper aims to present a discussion about intrinsic nursing knowledge. The paper stems from the author's study of knowledge claims enshrined in nursing journal articles, books and conference speeches. It is argued that claims by academic nurses have largely depended on principles drawn from continental and not Analytic (British-American) philosophy. Thus, claims are credible only insofar as they defer propositional logic. This is problematic inasmuch as nursing is a practice-based activity usually carried out in medical settings. Transpersonal nursing models are particularly criticizable in respect of their unworldly character as are also concepts based on shallow usages of physics or mathematics. I argue that sensible measurements of the 'real world' are possible--without endorsing positivism--and that nursing requires little recourse to logically unsustainable claims. The paper concludes with an analysis of a recent review of nursing knowledge, which analysis indicates the circularity that attends many discussions on the topic. © 2011 Blackwell Publishing.

  1. Equality Act 2010: knowledge, perceptions and practices of occupational physicians.

    PubMed

    Masupe, T; Parker, G

    2013-04-01

    Historically, many prospective employees in Great Britain have undergone pre-employment health screening (PEHS) assessments before a job offer. Section 60 of the Equality Act 2010 stipulates that PEHS assessments before a job offer may contravene the disability provisions of the Act except under specific circumstances. PEHS assessments in the current format may not fully comply with the provisions of the legislation. To describe the knowledge, perceptions and practices of occupational health physicians in UK following implementation of the Equality Act 2010. Data were collected through an anonymous online survey of occupational health physicians (OHPs) actively reporting to the Occupational Physicians Reporting Activity (OPRA) at the Centre for Occupational and Environmental Health, the University of Manchester. There were 126 responses available for analysis (response rate 43%). Most participants (81%) were accredited occupational health specialists providing occupational health advice to various industry sectors; 96% reported involvement in PEHS assessments; 81% reported awareness of section 60 of the Equality Act 2010. Further analysis of these participants revealed varying knowledge levels and practices relating to specific requirements of section 60. Changes in professional practice resulting from the Act were reported by 38%, while 46% reported no change. There have been minimal immediate changes to PEHS practices by OHPs in response to section 60 of the Act. Some OHPs displayed inadequate knowledge of specific requirements of section 60 of the Act. OHPs could benefit from further training on specific requirements of this legislation.

  2. Perspectives on knowledge in engineering design

    NASA Technical Reports Server (NTRS)

    Rasdorf, W. J.

    1985-01-01

    Various perspectives are given of the knowledge currently used in engineering design, specifically dealing with knowledge-based expert systems (KBES). Constructing an expert system often reveals inconsistencies in domain knowledge while formalizing it. The types of domain knowledge (facts, procedures, judgments, and control) differ from the classes of that knowledge (creative, innovative, and routine). The feasible tasks for expert systems can be determined based on these types and classes of knowledge. Interpretive tasks require reasoning about a task in light of the knowledge available, where generative tasks create potential solutions to be tested against constraints. Only after classifying the domain by type and level can the engineer select a knowledge-engineering tool for the domain being considered. The critical features to be weighed after classification are knowledge representation techniques, control strategies, interface requirements, compatibility with traditional systems, and economic considerations.

  3. 10 CFR 73.50 - Requirements for physical protection of licensed activities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Requirements for physical protection of licensed activities. 73.50 Section 73.50 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PHYSICAL PROTECTION OF PLANTS AND MATERIALS Physical Protection Requirements at Fixed Sites § 73.50 Requirements for physical...

  4. 10 CFR 73.50 - Requirements for physical protection of licensed activities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Requirements for physical protection of licensed activities. 73.50 Section 73.50 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PHYSICAL PROTECTION OF PLANTS AND MATERIALS Physical Protection Requirements at Fixed Sites § 73.50 Requirements for physical...

  5. 49 CFR 383.110 - General requirement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... STANDARDS; REQUIREMENTS AND PENALTIES Required Knowledge and Skills § 383.110 General requirement. All drivers of CMVs must have the knowledge and skills necessary to operate a CMV safely as contained in this subpart. The specific types of items that a State must include in the knowledge and skills tests that it...

  6. Parental Strategies for Knowledge of Adolescents’ Friends: Distinct from Monitoring?

    PubMed Central

    Miller, Brenda A.; Duke, Michael R.; Ames, Genevieve M.

    2012-01-01

    Parental monitoring is defined as a set of behaviors used to gain knowledge about an adolescent’s whereabouts, friends and associates, and activities. However, can knowledge of adolescents’ whereabouts/activities, and friends all be attained through the same strategies? Or do they require their own strategies? This study used qualitative interviews with 173 parents of older adolescents from 100 families. Emergent themes described strategies by which parents gain information about their adolescents’ friends and the substance use of those friends. The strategies included direct interaction with the friend, gaining information from the teen, using second-hand sources, and making assumptions. Some of these strategies were consistent with previous research, while others raise new questions and provide interesting new directions to pursue. Primarily, additional consideration needs to be given to assessments of parental monitoring that include strategies for gaining knowledge of adolescents’ friends and their substance use. PMID:23209361

  7. The effects of an infant-feeding classroom activity on the breast-feeding knowledge and intentions of adolescents.

    PubMed

    Walsh, Audrey; Moseley, Jane; Jackson, Winston

    2008-06-01

    This study examined the impact of an infant-feeding classroom activity on the breast-feeding knowledge and intentions of adolescents living in Nova Scotia, Canada. One hundred twenty-one students attending two high schools were administered one pretest and two posttest questionnaires. Students were arbitrarily assigned to a control or intervention group. The intervention group partook in a 60-minute classroom activity on infant feeding. Findings indicated that students in the intervention group demonstrated significantly greater breast-feeding knowledge at Posttest 1 and at 10 weeks postintervention. Students in the intervention group reported a significantly greater intention toward breast-feeding their own future children; an increase was sustained at 10 weeks. These findings suggest that adolescents' knowledge of and intention toward breast-feeding may be positively influenced during their teen years. School nurses are well positioned to support and encourage the inclusion of breast-feeding content in school curricula to enhance adolescents' knowledge and intentions toward breast-feeding.

  8. 14 CFR 63.35 - Knowledge requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... aerodynamics. (3) Basic meteorology with respect to engine operations. (4) Center of gravity computations. (b... written test, is employed as a flight crewmember or mechanic by a U.S. air carrier or commercial operator... training; and (iii) Meets the recurrent training requirements of the applicable part or, for mechanics...

  9. 14 CFR 63.35 - Knowledge requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... aerodynamics. (3) Basic meteorology with respect to engine operations. (4) Center of gravity computations. (b... written test, is employed as a flight crewmember or mechanic by a U.S. air carrier or commercial operator... training; and (iii) Meets the recurrent training requirements of the applicable part or, for mechanics...

  10. 14 CFR 63.35 - Knowledge requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... aerodynamics. (3) Basic meteorology with respect to engine operations. (4) Center of gravity computations. (b... written test, is employed as a flight crewmember or mechanic by a U.S. air carrier or commercial operator... training; and (iii) Meets the recurrent training requirements of the applicable part or, for mechanics...

  11. 14 CFR 63.35 - Knowledge requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... aerodynamics. (3) Basic meteorology with respect to engine operations. (4) Center of gravity computations. (b... written test, is employed as a flight crewmember or mechanic by a U.S. air carrier or commercial operator... training; and (iii) Meets the recurrent training requirements of the applicable part or, for mechanics...

  12. Activating knowledge for patient safety practices: a Canadian academic-policy partnership.

    PubMed

    Harrison, Margaret B; Nicklin, Wendy; Owen, Marie; Godfrey, Christina; McVeety, Janice; Angus, Val

    2012-02-01

    Over the past decade, the need for healthcare delivery systems to identify and address patient safety issues has been propelled to the forefront. A Canadian survey, for example, demonstrated patient safety to be a major concern of frontline nurses (Nicklin & McVeety 2002). Three crucial patient safety elements, current knowledge, resources, and context of care have been identified by the World Health Organization (WHO 2009). To develop strategies to respond to the scope and mandate of the WHO report within the Canadian context, a pan-Canadian academic-policy partnership has been established. This newly formed Pan-Canadian Partnership, the Queen's Joanna Briggs Collaboration for Patient Safety (referred throughout as "QJBC" or "the Partnership"), includes the Queen's University School of Nursing, Accreditation Canada, the Canadian Patient Safety Institute (CPSI), the Canadian Institutes of Health Research, and is supported by an active and committed advisory council representing over 10 national organizations representing all sectors of the health continuum, including patients/families advocacy groups, professional associations, and other bodies. This unique partnership is designed to provide timely, focused support from academia to the front line of patient safety. QJBC has adopted an "integrated knowledge translation" approach to identify and respond to patient safety priorities and to ensure active engagement with stakeholders in producing and using available knowledge. Synthesis of evidence and guideline adaptation methodologies are employed to access quantitative and qualitative evidence relevant to pertinent patient safety questions and subsequently, to respond to issues of feasibility, meaningfulness, appropriateness/acceptability, and effectiveness. This paper describes the conceptual grounding of the Partnership, its proposed methods, and its plan for action. It is hoped that our journey may provide some guidance to others as they develop patient safety

  13. Understanding the Knowledge Environment

    DTIC Science & Technology

    2011-01-01

    understand , learn, and apply the processes, technologies, principles, and strategies required in a self aware and adaptive Army. The knowledge , skills...resource. In the mid-90s, the term ‘ knowledge management’ was used to address the shortcomings of information technology to deliver on the promise of...application of tacit knowledge (the knowledge in our heads) has replaced the who, what, when, and where questions that provided us only information . As

  14. Working with the Cold War: Types of Knowledge in Swedish and Australian History Textbook Activities

    ERIC Educational Resources Information Center

    Ammert, Niklas; Sharp, Heather

    2016-01-01

    This article presents a comparative analysis of pupils' activities dealing with the Cold War in Swedish and Australian history textbooks. By focusing on textbook activities to which pupils respond in relation to their learning of a particular topic, this study identifies knowledge types included in a selection of history textbooks. The study also…

  15. Ninth Graders' Energy Balance Knowledge and Physical Activity Behavior: An Expectancy-Value Perspective

    ERIC Educational Resources Information Center

    Chen, Senlin; Chen, Ang

    2012-01-01

    Expectancy beliefs and task values are two essential motivators in physical education. This study was designed to identify the relation between the expectancy-value constructs (Eccles & Wigfield, 1995) and high school students' physical activity behavior as associated with their energy balance knowledge. High school students (N = 195) in two…

  16. Research on knowledge representation, machine learning, and knowledge acquisition

    NASA Technical Reports Server (NTRS)

    Buchanan, Bruce G.

    1987-01-01

    Research in knowledge representation, machine learning, and knowledge acquisition performed at Knowledge Systems Lab. is summarized. The major goal of the research was to develop flexible, effective methods for representing the qualitative knowledge necessary for solving large problems that require symbolic reasoning as well as numerical computation. The research focused on integrating different representation methods to describe different kinds of knowledge more effectively than any one method can alone. In particular, emphasis was placed on representing and using spatial information about three dimensional objects and constraints on the arrangement of these objects in space. Another major theme is the development of robust machine learning programs that can be integrated with a variety of intelligent systems. To achieve this goal, learning methods were designed, implemented and experimented within several different problem solving environments.

  17. Employer knowledge of federal requirements for recording work-related injuries and illnesses: Implications for occupational injury surveillance data.

    PubMed

    Wuellner, Sara; Phipps, Polly

    2018-05-01

    Accuracy of the Bureau of Labor Statistics Survey of Occupational Injuries and Illnesses (SOII) data is dependent on employer compliance with workplace injury and illness recordkeeping requirements. Characterization of employer recordkeeping can inform efforts to improve the data. We interviewed representative samples of SOII respondents from four states to identify common recordkeeping errors and to assess employer characteristics associated with limited knowledge of the recordkeeping requirements and non compliant practices. Less than half of the establishments required to maintain OSHA injury and illness records reported doing so. Few establishments knew to omit cases limited to diagnostic services (22%) and to count unscheduled weekend days as missed work (27%). No single state or establishment characteristic was consistently associated with better or worse record-keeping. Many employers possess a limited understanding of workplace injury recordkeeping requirements, potentially leading them to over-report minor incidents, and under-report missed work cases. © 2018 Wiley Periodicals, Inc.

  18. Effect of Body Composition, Physical Activity, and Aerobic Fitness on the Physical Activity and Fitness Knowledge of At-Risk Inner-City Children

    ERIC Educational Resources Information Center

    Brusseau, Timothy A.; Burns, Ryan D.; Hannon, James C.

    2016-01-01

    SHAPE America has highlighted the importance of developing physically literate children as part of quality physical education programming. Unfortunately, most children know little about physical activity and health-related fitness. The purpose of this study was to examine the physical activity and fitness content knowledge of at-risk inner-city…

  19. Knowledge is (not) power: healthy eating and physical activity for African-American women.

    PubMed

    Barnett, Tracey Marie; Praetorius, Regina T

    2015-01-01

    African-American women are more likely to be overweight or obese as compared to other ethnic groups. The purpose of this Qualitative Interpretive Meta-Synthesis (QIMS) was to explore the experiences that African-American women encounter when trying to eat healthily and maintain physical activity to inform practice and research. The QIMS included studies from various disciplines to understand the experiences of African-American women with eating healthily and being physically active. Five themes were identified: family; structured support; translating knowledge into behavior modifications; barriers to physical activity; and God is my healer. These themes enhance understanding of what African-American women know, their support system(s), and how cultural barriers impact nutrition and physical activity.

  20. Knowledge, attitudes, and behavior concerning nutrition and physical activity in Mexican children.

    PubMed

    Escalante-Guerrero, Claudia Susana; De la Roca-Chiapas, José María; Macías-Cervantes, Maciste Habacuc

    2012-03-01

    To identify the stages of behavior change and the knowledge, attitudes, and habits concerning nutrition and physical activity in Mexican children. A survey was applied to 48 children from 10 years old to obtain data. Stages of behavior change were classified according to the transtheoretical model. For food habits, 31% were in precontemplation, 17% in contemplation, 10% in preparation, 40% in action, and 2% in maintenance. For physical activity, 12% were in precontemplation, 15% in contemplation, 29% in preparation, 42% in action, and 2% in maintenance. It is important to consider the stages of behavior change to plan strategies of educational models.

  1. Knowledge Activation and Schema Construction.

    ERIC Educational Resources Information Center

    Alvarez, Marino C.

    This study examined how instruction that encourages critical thinking about what has been read can lead to incorporated knowledge that can be retrieved and applied to other related settings. Case-based learning (an instructional method long used with graduate business, law, and medical students) is one method that can be used to foster critical…

  2. Murine Polyomavirus Cell Surface Receptors Activate Distinct Signaling Pathways Required for Infection.

    PubMed

    O'Hara, Samantha D; Garcea, Robert L

    2016-11-01

    Virus binding to the cell surface triggers an array of host responses, including activation of specific signaling pathways that facilitate steps in virus entry. Using mouse polyomavirus (MuPyV), we identified host signaling pathways activated upon virus binding to mouse embryonic fibroblasts (MEFs). Pathways activated by MuPyV included the phosphatidylinositol 3-kinase (PI3K), FAK/SRC, and mitogen-activated protein kinase (MAPK) pathways. Gangliosides and α4-integrin are required receptors for MuPyV infection. MuPyV binding to both gangliosides and the α4-integrin receptors was required for activation of the PI3K pathway; however, either receptor interaction alone was sufficient for activation of the MAPK pathway. Using small-molecule inhibitors, we confirmed that the PI3K and FAK/SRC pathways were required for MuPyV infection, while the MAPK pathway was dispensable. Mechanistically, the PI3K pathway was required for MuPyV endocytosis, while the FAK/SRC pathway enabled trafficking of MuPyV along microtubules. Thus, MuPyV interactions with specific cell surface receptors facilitate activation of signaling pathways required for virus entry and trafficking. Understanding how different viruses manipulate cell signaling pathways through interactions with host receptors could lead to the identification of new therapeutic targets for viral infection. Virus binding to cell surface receptors initiates outside-in signaling that leads to virus endocytosis and subsequent virus trafficking. How different viruses manipulate cell signaling through interactions with host receptors remains unclear, and elucidation of the specific receptors and signaling pathways required for virus infection may lead to new therapeutic targets. In this study, we determined that gangliosides and α4-integrin mediate mouse polyomavirus (MuPyV) activation of host signaling pathways. Of these pathways, the PI3K and FAK/SRC pathways were required for MuPyV infection. Both the PI3K and FAK/SRC pathways

  3. 20 CFR 404.1311 - Ninety-day active service requirement for World War II veterans.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Ninety-day active service requirement for... Uniformed Services World War II Veterans § 404.1311 Ninety-day active service requirement for World War II veterans. (a) The 90 days of active service required for World War II veterans do not have to be...

  4. 20 CFR 404.1311 - Ninety-day active service requirement for World War II veterans.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Ninety-day active service requirement for... Uniformed Services World War II Veterans § 404.1311 Ninety-day active service requirement for World War II veterans. (a) The 90 days of active service required for World War II veterans do not have to be...

  5. 20 CFR 404.1311 - Ninety-day active service requirement for World War II veterans.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Ninety-day active service requirement for... Uniformed Services World War II Veterans § 404.1311 Ninety-day active service requirement for World War II veterans. (a) The 90 days of active service required for World War II veterans do not have to be...

  6. Physical Activity and Fitness Knowledge Learning in Physical Education: Seeking a Common Ground

    ERIC Educational Resources Information Center

    Chen, Senlin; Chen, Ang; Sun, Haichun; Zhu, Xihe

    2013-01-01

    Motivation to learn is a disposition developed through exposure to learning opportunities. Guided by the expectancy-value theory of Eccles and Wigfield (1995), this study examined the extent to which expectancy belief and task value influenced elementary school students' physical activity and knowledge learning in physical education (PE).…

  7. Reading Comprehension Requires Knowledge--of Words and the World.

    ERIC Educational Resources Information Center

    Hirsch, E. D., Jr.

    2003-01-01

    The "fourth grade slump" in reading comprehension still exists. Among poor children, low comprehension ruins their chances for academic success. Among all children, comprehension scores are stagnant. Research indicates that key to both problems is systematically building children's vocabulary, fluency, and domain knowledge. To improve reading,…

  8. Enhancing health care professionals' and trainees' knowledge of physical activity guidelines for adults with and without SCI.

    PubMed

    Shirazipour, Celina H; Tomasone, Jennifer R; Martin Ginis, Kathleen A

    2018-01-11

    Health care providers (HCPs) are preferred sources of physical activity (PA) information; however, minimal research has explored HCPs' knowledge of spinal cord injury (SCI) PA guidelines, and no research has examined HCP trainees' PA guideline knowledge. The current study explored HCPs' and trainees' initial knowledge of PA guidelines for both adults with SCI and the general population, and the utility of an event-based intervention for improving this knowledge. Participants (HCPs n = 129; trainees n = 573) reported guideline knowledge for both sets of guidelines (SCI and general population) immediately after, one-month, and six-months following the intervention. Frequencies determined guideline knowledge at each timepoint, while chi-squared tests examined differences in knowledge of both guidelines, as well as knowledge differences in the short- and long-term. Results demonstrated that HCPs and trainees lack knowledge of PA guidelines, particularly guidelines for adults with SCI. The results further suggest that a single event-based intervention is not effective for improving long-term guideline knowledge. Suggestions are made for future research with the aim of improving interventions that target HCP and HCP trainees' long-term guideline knowledge for adults with SCI and the general population.

  9. Behaviors and Knowledge of HealthCorps New York City High School Students: Nutrition, Mental Health and Physical Activity

    PubMed Central

    Moonseong, Heo; Erica, Irvin; Natania, Ostrovsky; Carmen, Isasi; Shawn, Hayes; Judith, Wylie-Rosett

    2015-01-01

    BACKGROUND HealthCorps provides school wellness programming using curricula to promote changes in nutrition, mental health and physical activity behaviors. The research objective was to evaluate effects of implementing its curricula on nutrition, mental health and physical activity knowledge and behavior. METHODS Pre- and post-survey data were collected (N = 2255) during the 2012-13 academic year from 14 New York City public high schools. An 18-item knowledge questionnaire addressed 3 domains; 26 behavioral items were analyzed by factor analysis to identify 6 behavior domains, breakfast being a seventh one-item domain. We examined the effects stratified by sex, applying mixed-effects models to take into account clustering effects of schools and participants adjusted for age. RESULTS The HealthCorps program significantly increased all 3 knowledge domains (p < .05), and significantly changed several key behavioral domains. Boys significantly increased fruits/vegetables intake (p = .03). Girls increased acceptance of new fruits/vegetables (p = .03) and breakfast consumption (p = .04), and decreased sugar-sweetened beverages and energy dense food intake (p = .03). The associations between knowledge and behavior were stronger in boys than girls. CONCLUSION The HealthCorps program significantly increased participants’ knowledge on nutrition, mental health and physical activity. It also improved several key behavioral domains, which are targets of the 2010 Dietary Guidelines to address obesity in youth. PMID:26762819

  10. Behaviors and Knowledge of HealthCorps New York City High School Students: Nutrition, Mental Health, and Physical Activity.

    PubMed

    Heo, Moonseong; Irvin, Erica; Ostrovsky, Natania; Isasi, Carmen; Blank, Arthur E; Lounsbury, David W; Fredericks, Lynn; Yom, Tiana; Ginsberg, Mindy; Hayes, Shawn; Wylie-Rosett, Judith

    2016-02-01

    HealthCorps provides school wellness programming using curricula to promote changes in nutrition, mental health, and physical activity behaviors. The research objective was to evaluate effects of implementing its curricula on nutrition, mental health, and physical activity knowledge and behavior. Pre- and postsurvey data were collected (N = 2255) during the 2012-2013 academic year from 14 New York City public high schools. An 18-item knowledge questionnaire addressed 3 domains; 26 behavioral items were analyzed by factor analysis to identify 6 behavior domains, breakfast being a seventh 1-item domain. We examined the effects stratified by sex, applying mixed-effects models to take into account clustering effects of schools and participants adjusted for age. The HealthCorps program significantly increased all 3 knowledge domains (p < .05), and significantly changed several key behavioral domains. Boys significantly increased fruits/vegetables intake (p = .03). Girls increased acceptance of new fruits/vegetables (p = .03) and breakfast consumption (p = .04), and decreased sugar-sweetened beverages and energy dense food intake (p = .03). The associations between knowledge and behavior were stronger in boys than girls. The HealthCorps program significantly increased participants' knowledge on nutrition, mental health, and physical activity. It also improved several key behavioral domains, which are targets of the 2010 Dietary Guidelines to address obesity in youth. © 2016, American School Health Association.

  11. The Costs of Knowledge

    NASA Technical Reports Server (NTRS)

    Prusak, Laurence

    2008-01-01

    Acquiring knowledge-genuinely learning something new-requires the consent and commitment of the person you're trying to learn from. In contrast to information, which can usually be effectively transmitted in a document or diagram, knowledge comes from explaining, clarifying, questioning, and sometimes actually working together. Getting this kind of attention and commitment often involves some form of negotiation, since even the most generous person's time and energy are limited. Few experts sit around waiting to share their knowledge with strangers or casual acquaintances. In reasonably collaborative enterprises- I think NASA is one-this sort of negotiation isn't too onerous. People want to help each other and share what they know, so the "cost" of acquiring knowledge is relatively low. In many organizations (and many communities and countries), however, there are considerable costs associated with this activity, and many situations in which negotiations fail. The greatest knowledge cost is in and adopting knowledge to one's own use. Sometimes this means formally organizing what one learns in writing. Sometimes it means just taking time to reflect on someone else's thoughts and experiences-thinking about knowledge that is not exactly what you need but can lead you to develop ideas that will be useful. A long, discursive conversation, with all the back-and-forth that defines conversation, can be a mechanism of knowledge exchange. I have seen many participants at NASA APPEL Masters Forums talking, reflecting, and thinking-adapting what they are hearing to their own needs. Knowledge transfer is not a simple proposition. An enormous amount of information flows through the world every day, but knowledge is local, contextual, and "stickyn-that is, it takes real effort to move it from one place to another. There is no way around this. To really learn a subject, you have to work at it, you have to pay your "knowledge dues." So while, thanks to advances in technology

  12. Mobile, Collaborative Situated Knowledge Creation for Urban Planning

    PubMed Central

    Zurita, Gustavo; Baloian, Nelson

    2012-01-01

    Geo-collaboration is an emerging research area in computer sciences studying the way spatial, geographically referenced information and communication technologies can support collaborative activities. Scenarios in which information associated to its physical location are of paramount importance are often referred as Situated Knowledge Creation scenarios. To date there are few computer systems supporting knowledge creation that explicitly incorporate physical context as part of the knowledge being managed in mobile face-to-face scenarios. This work presents a collaborative software application supporting visually-geo-referenced knowledge creation in mobile working scenarios while the users are interacting face-to-face. The system allows to manage data information associated to specific physical locations for knowledge creation processes in the field, such as urban planning, identifying specific physical locations, territorial management, etc.; using Tablet-PCs and GPS in order to geo-reference data and information. It presents a model for developing mobile applications supporting situated knowledge creation in the field, introducing the requirements for such an application and the functionalities it should have in order to fulfill them. The paper also presents the results of utility and usability evaluations. PMID:22778639

  13. Mobile, collaborative situated knowledge creation for urban planning.

    PubMed

    Zurita, Gustavo; Baloian, Nelson

    2012-01-01

    Geo-collaboration is an emerging research area in computer sciences studying the way spatial, geographically referenced information and communication technologies can support collaborative activities. Scenarios in which information associated to its physical location are of paramount importance are often referred as Situated Knowledge Creation scenarios. To date there are few computer systems supporting knowledge creation that explicitly incorporate physical context as part of the knowledge being managed in mobile face-to-face scenarios. This work presents a collaborative software application supporting visually-geo-referenced knowledge creation in mobile working scenarios while the users are interacting face-to-face. The system allows to manage data information associated to specific physical locations for knowledge creation processes in the field, such as urban planning, identifying specific physical locations, territorial management, etc.; using Tablet-PCs and GPS in order to geo-reference data and information. It presents a model for developing mobile applications supporting situated knowledge creation in the field, introducing the requirements for such an application and the functionalities it should have in order to fulfill them. The paper also presents the results of utility and usability evaluations.

  14. Requirements for color technology

    NASA Astrophysics Data System (ADS)

    Campbell, Ronald B., Jr.

    1993-06-01

    The requirements for color technology in the general office are reviewed. The two most salient factors driving the requirements for color are the information explosion and the virtually negligible growth in white collar productivity in the recent past. Accordingly, the business requirement upon color technology is that it be utilized in an effective and efficient manner to increase office productivity. Recent research on productivity and growth has moved beyond the classical two factor productivity model of labor and capital to explicitly include knowledge as a third and vital factor. Documents are agents of knowledge in the general office. Documents articulate, express, disseminate, and communicate knowledge. The central question addressed here is how can color, in conjunction with other techniques such as graphics and document design, improve the growth of knowledge? The central thesis is that the effective use of color to convert information into knowledge is one of the most powerful ways to increase office productivity. Material on the value of color is reviewed. This material is related to the role of documents. Document services are the way in which users access and utilize color technology. The requirements for color technology are then defined against the services taxonomy.

  15. 49 CFR Appendix to Subpart G of... - Required Knowledge and Skills-Sample Guidelines

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... knowledge and skills tests that it administers to CDL applicants. This appendix closely follows the... discretion provided their CDL program tests for the general areas of knowledge and skill specified in §§ 383.111 and 383.113. Examples of specific knowledge elements (a) Safe operations regulations. Driver...

  16. Intracultural Differences in Local Botanical Knowledge and Knowledge Loss among the Mexican Isthmus Zapotecs.

    PubMed

    Saynes-Vásquez, Alfredo; Vibrans, Heike; Vergara-Silva, Francisco; Caballero, Javier

    2016-01-01

    This study reports on the socio-demographic and locality factors that influence ethnobiological knowledge in three communities of Zapotec indigenous people of the Isthmus of Tehuantepec, Mexico. It uses local botanical nomenclature as a proxy for general ethnobiological knowledge. In each of these communities (one urban and two rural), 100 adult men were interviewed aided with a field herbarium. Fifty had a background in farming, and 50 worked in the secondary or tertiary sector as their main economic activity, totaling 300 interviews. Using a field herbarium with samples of 30 common and rare wild regional species, we documented visual recognition, knowledge of the local life form, generic and specific names and uses (five knowledge levels measuring knowledge depth). The relationship between sociodemographic variables and knowledge was analyzed with simple correlations. Differences between the three communities and the five knowledge levels were then evaluated with a discriminant analysis. A general linear analysis identified factors and covariables that influenced the observed differences. Differences between the groups with different economic activities were estimated with a t-test for independent samples. Most of the relationships found between sociodemographic variables and plant knowledge were expected: age and rurality were positively related with knowledge and years of formal schooling was negatively related. However, the somewhat less rural site had more traditional knowledge due to local circumstances. The general linear model explained 70-77% of the variation, a high value. It showed that economic activity was by far the most important factor influencing knowledge, by a factor of five. The interaction of locality and economic activity followed. The discriminant analysis assigned interviewees correctly to their localities in 94% of the cases, strengthening the evidence for intracultural variation. Both sociodemographic and historic intracultural

  17. Intracultural Differences in Local Botanical Knowledge and Knowledge Loss among the Mexican Isthmus Zapotecs

    PubMed Central

    Saynes-Vásquez, Alfredo; Vibrans, Heike; Vergara-Silva, Francisco; Caballero, Javier

    2016-01-01

    This study reports on the socio-demographic and locality factors that influence ethnobiological knowledge in three communities of Zapotec indigenous people of the Isthmus of Tehuantepec, Mexico. It uses local botanical nomenclature as a proxy for general ethnobiological knowledge. In each of these communities (one urban and two rural), 100 adult men were interviewed aided with a field herbarium. Fifty had a background in farming, and 50 worked in the secondary or tertiary sector as their main economic activity, totaling 300 interviews. Using a field herbarium with samples of 30 common and rare wild regional species, we documented visual recognition, knowledge of the local life form, generic and specific names and uses (five knowledge levels measuring knowledge depth). The relationship between sociodemographic variables and knowledge was analyzed with simple correlations. Differences between the three communities and the five knowledge levels were then evaluated with a discriminant analysis. A general linear analysis identified factors and covariables that influenced the observed differences. Differences between the groups with different economic activities were estimated with a t-test for independent samples. Most of the relationships found between sociodemographic variables and plant knowledge were expected: age and rurality were positively related with knowledge and years of formal schooling was negatively related. However, the somewhat less rural site had more traditional knowledge due to local circumstances. The general linear model explained 70–77% of the variation, a high value. It showed that economic activity was by far the most important factor influencing knowledge, by a factor of five. The interaction of locality and economic activity followed. The discriminant analysis assigned interviewees correctly to their localities in 94% of the cases, strengthening the evidence for intracultural variation. Both sociodemographic and historic intracultural

  18. Nutrition and physical activity randomized control trial in child care centers improves knowledge, policies, and children's body mass index.

    PubMed

    Alkon, Abbey; Crowley, Angela A; Neelon, Sara E Benjamin; Hill, Sherika; Pan, Yi; Nguyen, Viet; Rose, Roberta; Savage, Eric; Forestieri, Nina; Shipman, Linda; Kotch, Jonathan B

    2014-03-01

    To address the public health crisis of overweight and obese preschool-age children, the Nutrition And Physical Activity Self Assessment for Child Care (NAP SACC) intervention was delivered by nurse child care health consultants with the objective of improving child care provider and parent nutrition and physical activity knowledge, center-level nutrition and physical activity policies and practices, and children's body mass index (BMI). A seven-month randomized control trial was conducted in 17 licensed child care centers serving predominantly low income families in California, Connecticut, and North Carolina, including 137 child care providers and 552 families with racially and ethnically diverse children three to five years old. The NAP SACC intervention included educational workshops for child care providers and parents on nutrition and physical activity and consultation visits provided by trained nurse child care health consultants. Demographic characteristics and pre - and post-workshop knowledge surveys were completed by providers and parents. Blinded research assistants reviewed each center's written health and safety policies, observed nutrition and physical activity practices, and measured randomly selected children's nutritional intake, physical activity, and height and weight pre- and post-intervention. Hierarchical linear models and multiple regression models assessed individual- and center-level changes in knowledge, policies, practices and age- and sex-specific standardized body mass index (zBMI), controlling for state, parent education, and poverty level. Results showed significant increases in providers' and parents' knowledge of nutrition and physical activity, center-level improvements in policies, and child-level changes in children's zBMI based on 209 children in the intervention and control centers at both pre- and post-intervention time points. The NAP SACC intervention, as delivered by trained child health professionals such as child care

  19. Frequent Surfing on Social Health Networks is Associated With Increased Knowledge and Patient Health Activation

    PubMed Central

    Grosberg, Dafna; Grinvald, Haya; Reuveni, Haim

    2016-01-01

    Background The advent of the Internet has driven a technological revolution that has changed our lives. As part of this phenomenon, social networks have attained a prominent role in health care. A variety of medical services is provided over the Internet, including home monitoring, interactive communications between the patient and service providers, and social support, among others. This study emphasizes some of the practical implications of Web-based health social networks for patients and for health care systems. Objective The objective of this study was to assess how participation in a social network among individuals with a chronic condition contributed to patient activation, based on the Patient Activation Measure (PAM). Methods A prospective, cross-sectional survey with a retrospective component was conducted. Data were collected from Camoni, a Hebrew-language Web-based social health network, participants in the diabetes mellitus, pain, hypertension, and depression/anxiety forums, during November 2012 to 2013. Experienced users (enrolled at least 6 months) and newly enrolled received similar versions of the same questionnaire including sociodemographics and PAM. Results Among 686 participants, 154 of 337 experienced and 123 of 349 newly enrolled completed the questionnaire. Positive correlations (P<.05) were found between frequency and duration of site visits and patient activation, social relationships, and chronic disease knowledge. Men surfed longer than women (χ²3=10.104, P<.05). Experienced users with diabetes surfed more than those with other illnesses and had significantly higher PAM scores (mean, M=69.3, standard deviation, SD=19.1, PAM level 4; Z=−4.197, P<.001) than new users (M=62.8, SD=18.7, PAM level 3). Disease knowledge directly predicted PAM for all users (β=.26 and .21, respectively). Frequency and duration of social health network use were correlated with increased knowledge about a chronic disease. Experienced surfers had higher PAM

  20. Frequent Surfing on Social Health Networks is Associated With Increased Knowledge and Patient Health Activation.

    PubMed

    Grosberg, Dafna; Grinvald, Haya; Reuveni, Haim; Magnezi, Racheli

    2016-08-10

    The advent of the Internet has driven a technological revolution that has changed our lives. As part of this phenomenon, social networks have attained a prominent role in health care. A variety of medical services is provided over the Internet, including home monitoring, interactive communications between the patient and service providers, and social support, among others. This study emphasizes some of the practical implications of Web-based health social networks for patients and for health care systems. The objective of this study was to assess how participation in a social network among individuals with a chronic condition contributed to patient activation, based on the Patient Activation Measure (PAM). A prospective, cross-sectional survey with a retrospective component was conducted. Data were collected from Camoni, a Hebrew-language Web-based social health network, participants in the diabetes mellitus, pain, hypertension, and depression/anxiety forums, during November 2012 to 2013. Experienced users (enrolled at least 6 months) and newly enrolled received similar versions of the same questionnaire including sociodemographics and PAM. Among 686 participants, 154 of 337 experienced and 123 of 349 newly enrolled completed the questionnaire. Positive correlations (P<.05) were found between frequency and duration of site visits and patient activation, social relationships, and chronic disease knowledge. Men surfed longer than women (χ²3=10.104, P<.05). Experienced users with diabetes surfed more than those with other illnesses and had significantly higher PAM scores (mean, M=69.3, standard deviation, SD=19.1, PAM level 4; Z=-4.197, P<.001) than new users (M=62.8, SD=18.7, PAM level 3). Disease knowledge directly predicted PAM for all users (β=.26 and .21, respectively). Frequency and duration of social health network use were correlated with increased knowledge about a chronic disease. Experienced surfers had higher PAM than newly enrolled, suggesting that

  1. TRIM25 Is Required for the Antiviral Activity of Zinc Finger Antiviral Protein

    PubMed Central

    Zheng, Xiaojiao; Wang, Xinlu; Tu, Fan; Wang, Qin; Fan, Zusen

    2017-01-01

    ABSTRACT Zinc finger antiviral protein (ZAP) is a host factor that specifically inhibits the replication of certain viruses by binding to viral mRNAs and repressing the translation and/or promoting the degradation of target mRNA. In addition, ZAP regulates the expression of certain cellular genes. Here, we report that tripartite motif-containing protein 25 (TRIM25), a ubiquitin E3 ligase, is required for the antiviral activity of ZAP. Downregulation of endogenous TRIM25 abolished ZAP's antiviral activity. The E3 ligase activity of TRIM25 is required for this regulation. TRIM25 mediated ZAP ubiquitination, but the ubiquitination of ZAP itself did not seem to be required for its antiviral activity. Downregulation of endogenous ubiquitin or overexpression of the deubiquitinase OTUB1 impaired ZAP's activity. We provide evidence indicating that TRIM25 modulates the target RNA binding activity of ZAP. These results uncover a mechanism by which the antiviral activity of ZAP is regulated. IMPORTANCE ZAP is a host antiviral factor that specifically inhibits the replication of certain viruses, including HIV-1, Sindbis virus, and Ebola virus. ZAP binds directly to target mRNA, and it represses the translation and promotes the degradation of target mRNA. While the mechanisms by which ZAP posttranscriptionally inhibits target RNA expression have been extensively studied, how its antiviral activity is regulated is not very clear. Here, we report that TRIM25, a ubiquitin E3 ligase, is required for the antiviral activity of ZAP. Downregulation of endogenous TRIM25 remarkably abolished ZAP's activity. TRIM25 is required for ZAP optimal binding to target mRNA. These results help us to better understand how the antiviral activity of ZAP is regulated. PMID:28202764

  2. TRIM25 Is Required for the Antiviral Activity of Zinc Finger Antiviral Protein.

    PubMed

    Zheng, Xiaojiao; Wang, Xinlu; Tu, Fan; Wang, Qin; Fan, Zusen; Gao, Guangxia

    2017-05-01

    Zinc finger antiviral protein (ZAP) is a host factor that specifically inhibits the replication of certain viruses by binding to viral mRNAs and repressing the translation and/or promoting the degradation of target mRNA. In addition, ZAP regulates the expression of certain cellular genes. Here, we report that tripartite motif-containing protein 25 (TRIM25), a ubiquitin E3 ligase, is required for the antiviral activity of ZAP. Downregulation of endogenous TRIM25 abolished ZAP's antiviral activity. The E3 ligase activity of TRIM25 is required for this regulation. TRIM25 mediated ZAP ubiquitination, but the ubiquitination of ZAP itself did not seem to be required for its antiviral activity. Downregulation of endogenous ubiquitin or overexpression of the deubiquitinase OTUB1 impaired ZAP's activity. We provide evidence indicating that TRIM25 modulates the target RNA binding activity of ZAP. These results uncover a mechanism by which the antiviral activity of ZAP is regulated. IMPORTANCE ZAP is a host antiviral factor that specifically inhibits the replication of certain viruses, including HIV-1, Sindbis virus, and Ebola virus. ZAP binds directly to target mRNA, and it represses the translation and promotes the degradation of target mRNA. While the mechanisms by which ZAP posttranscriptionally inhibits target RNA expression have been extensively studied, how its antiviral activity is regulated is not very clear. Here, we report that TRIM25, a ubiquitin E3 ligase, is required for the antiviral activity of ZAP. Downregulation of endogenous TRIM25 remarkably abolished ZAP's activity. TRIM25 is required for ZAP optimal binding to target mRNA. These results help us to better understand how the antiviral activity of ZAP is regulated. Copyright © 2017 American Society for Microbiology.

  3. 13 CFR 107.590 - Licensee's requirement to maintain active operations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... did not exceed 20 percent of your total assets (at cost) at your most recent fiscal year end. (b... lack of available funds, evidenced by Loans and Investments (at cost) equal to at least 90 percent of... requirements. The activity requirements in paragraph (a) of this section do not apply if you have filed a “Wind...

  4. 13 CFR 107.590 - Licensee's requirement to maintain active operations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... did not exceed 20 percent of your total assets (at cost) at your most recent fiscal year end. (b... lack of available funds, evidenced by Loans and Investments (at cost) equal to at least 90 percent of... requirements. The activity requirements in paragraph (a) of this section do not apply if you have filed a “Wind...

  5. 13 CFR 107.590 - Licensee's requirement to maintain active operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... did not exceed 20 percent of your total assets (at cost) at your most recent fiscal year end. (b... lack of available funds, evidenced by Loans and Investments (at cost) equal to at least 90 percent of... requirements. The activity requirements in paragraph (a) of this section do not apply if you have filed a “Wind...

  6. 13 CFR 107.590 - Licensee's requirement to maintain active operations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... did not exceed 20 percent of your total assets (at cost) at your most recent fiscal year end. (b... lack of available funds, evidenced by Loans and Investments (at cost) equal to at least 90 percent of... requirements. The activity requirements in paragraph (a) of this section do not apply if you have filed a “Wind...

  7. 13 CFR 107.590 - Licensee's requirement to maintain active operations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... did not exceed 20 percent of your total assets (at cost) at your most recent fiscal year end. (b... lack of available funds, evidenced by Loans and Investments (at cost) equal to at least 90 percent of... requirements. The activity requirements in paragraph (a) of this section do not apply if you have filed a “Wind...

  8. Mothers' Knowledge of Early Adolescents' Activities following the Middle School Transition and Pubertal Maturation

    ERIC Educational Resources Information Center

    Laird, Robert D.; Marrero, Matthew D.

    2011-01-01

    This study tested a sequential mediation model to determine whether experiences, social cognitions, or parent-adolescent interactional processes account for lower levels of mothers' knowledge of adolescents' whereabouts and activities following early adolescents' transition into middle school (MS) and pubertal development. Cross-sectional data…

  9. Knowledge mobilization in bridging patient-practitioner-researcher boundaries: A systematic integrative review protocol.

    PubMed

    Cowdell, Fiona; Booth, Andrew; Appleby, Ben

    2017-11-01

    To review published literature to identify when and how patients and healthcare practitioners have been involved in knowledge mobilization activity and the impact this may have had on their care. Improving patient outcomes, satisfaction and quality of care is increasingly reliant on shared decision-making between health professionals and patients. Knowledge mobilization, at its simplest: "moving knowledge to where it can be most useful" is a growing field of academic study. To date, it appears that much effort has focused on moving knowledge from researchers to healthcare practitioners. Knowledge mobilization to patients is currently under-researched. Integrative review. Methods of integrative review will be used to address the review problem. PRISMA guidelines were used as a general framework to guide structuring and reporting the review. Elements of method-specific reporting guidelines for specific streams of evidence will be used as required. This review will aim to provide a broad and deep understanding of patient-practitioner-researcher engagement in knowledge mobilization activity. This synthesis of the extant literature should offer insights into the optimum characteristics of methods for bridging patient-practitioner-researcher boundaries in knowledge mobilization action. © 2017 John Wiley & Sons Ltd.

  10. Alginate Lyase (AlgL) Activity Is Required for Alginate Biosynthesis in Pseudomonas aeruginosa

    PubMed Central

    Albrecht, Mark T.; Schiller, Neal L.

    2005-01-01

    To determine whether AlgL's lyase activity is required for alginate production in Pseudomonas aeruginosa, an algLΔ::Gmr mutant (FRD-MA7) was created. algL complementation of FRD-MA7 restored alginate production, but algL constructs containing mutations inactivating lyase activity did not, demonstrating that the enzymatic activity of AlgL is required for alginate production. PMID:15901714

  11. Scotland's knowledge network: a progress report on Knowledge into Action.

    PubMed

    Wales, Ann; Boyle, Derek

    2015-11-01

    Launched in 2012, Knowledge into Action is the national knowledge management strategy for the health and social care workforce in Scotland. It is transforming the role of the national digital knowledge service--NHS Education for Scotlands' Knowledge Network--and the NHSS librarian role to offer more active, tailored support for translating knowledge into frontline clinical practice. This includes the development of a national evidence search and summary service, help with converting knowledge into practical and usable formats for easy use at point of care and with using digital tools to share clinicians' learning, experience and expertise. Through this practical support, Knowledge into Action is contributing to quality and safety outcomes across NHS Scotland, building clinicians' capacity and capability in applying knowledge in frontline practice and service improvement. © The Author(s) 2015.

  12. The Medawar Lecture 2001 Knowledge for vision: vision for knowledge

    PubMed Central

    Gregory, Richard L

    2005-01-01

    An evolutionary development of perception is suggested—from passive reception to active perception to explicit conception—earlier stages being largely retained and incorporated in later species. A key is innate and then individually learned knowledge, giving meaning to sensory signals. Inappropriate or misapplied knowledge produces rich cognitive phenomena of illusions, revealing normally hidden processes of vision, tentatively classified here in a ‘peeriodic table’. Phenomena of physiology are distinguished from phenomena of general rules and specific object knowledge. It is concluded that vision uses implicit knowledge, and provides knowledge for intelligent behaviour and for explicit conceptual understanding including science. PMID:16147519

  13. Knowledge, Attitudes and Practices of Clinicians in Promoting Physical Activity to Prostate Cancer Survivors

    ERIC Educational Resources Information Center

    Spellman, Claire; Craike, Melinda; Livingston, Patricia M.

    2014-01-01

    Objectives: This study examined the knowledge, attitudes and practices of clinicians in promoting physical activity to prostate cancer survivors. Design: A purposeful sample was used and cross-sectional data were collected using an anonymous, self-reported online questionnaire or an identical paper-based questionnaire. Settings: Health services…

  14. Left prefrontal cortex activation during sentence comprehension covaries with grammatical knowledge in children.

    PubMed

    Knoll, L J; Obleser, J; Schipke, C S; Friederici, A D; Brauer, J

    2012-08-01

    Children's language skills develop rapidly with increasing age, and several studies indicate that they use language- and age-specific strategies to understand complex sentences. In the present experiment, functional magnetic resonance imaging (fMRI) and behavioral measures were used to investigate the acquisition of case-marking cues for sentence interpretation in the developing brain of German preschool children with a mean age of 6 years. Short sentences were presented auditorily, consisting of a transitive verb and two case-marked arguments with canonical subject-initial or non canonical object-initial word order. Overall group results revealed mainly left hemispheric activation in the perisylvian cortex with increased activation in the inferior parietal cortex (IPC), and the anterior cingulate cortex (ACC) for object-initial compared to subject-initial sentences. However, single-subject analysis suggested two distinct activation patterns within the group which allowed a classification into two subgroups. One subgroup showed the predicted activation increase in the left inferior frontal gyrus (IFG) for the more difficult object-initial compared to subject-initial sentences, while the other group showed the reverse effect. This activation in the left IFG can be taken to reflect the degree to which adult-like sentence processing strategies, necessary to integrate case-marking information, are applied. Additional behavioral data on language development tests show that these two subgroups differ in their grammatical knowledge. Together with these behavioral findings, the results indicate that the use of a particular processing strategy is not dependent on age as such, but rather on the child's individual grammatical knowledge and the ability to use specific language cues for successful sentence comprehension. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. Advanced extravehicular activity systems requirements definition study. Phase 2: Extravehicular activity at a lunar base

    NASA Technical Reports Server (NTRS)

    Neal, Valerie; Shields, Nicholas, Jr.; Carr, Gerald P.; Pogue, William; Schmitt, Harrison H.; Schulze, Arthur E.

    1988-01-01

    The focus is on Extravehicular Activity (EVA) systems requirements definition for an advanced space mission: remote-from-main base EVA on the Moon. The lunar environment, biomedical considerations, appropriate hardware design criteria, hardware and interface requirements, and key technical issues for advanced lunar EVA were examined. Six remote EVA scenarios (three nominal operations and three contingency situations) were developed in considerable detail.

  16. Rural patients' knowledge about heart failure.

    PubMed

    Dracup, Kathleen; Moser, Debra K; Pelter, Michele M; Nesbitt, Thomas; Southard, Jeffrey; Paul, Steven M; Robinson, Susan; Hemsey, Jessica Zègre; Cooper, Lawton

    2014-01-01

    Heart failure (HF) is a potentially disabling condition requiring significant patient knowledge to manage the requirements of self-care. The need for self-care is important for all patients but particularly for those living in rural areas that are geographically remote from healthcare services. The aim of this study was to identify the level of knowledge of rural patients with HF and the clinical and demographic characteristics associated with low levels of HF knowledge. Baseline data from 612 patients with HF enrolled in the Rural Education to Improve Outcomes in Heart Failure trial were analyzed using the Heart Failure Knowledge Scale, the Short Test of Functional Health Literacy in Adults, and the anxiety subscale of the Brief Symptom Inventory. Multiple linear regression was used to explore the contribution of sociodemographic and clinical variables to levels of HF knowledge. The mean (SD) age was 66 (13) years; 59% were men, and 50.5% had an ejection fraction of less than 40%. The mean (SD) percent correct on the Heart Failure Knowledge Scale was 69.5% (13%; range, 25%-100%), with the most frequent incorrect items related to symptoms of HF and the need for daily weights. The men and the older patients scored significantly lower in HF knowledge than did the women and the younger patients (P = 0.002 and 0.011, respectively). The patients with preserved systolic function also scored significantly lower than those with systolic HF (P = 0.030). Patients who are at risk for poor self-care because of low levels of HF knowledge can be identified. Older patients, men, and, patients with HF with preserved systolic function may require special educational strategies to gain the knowledge required for effective self-care.

  17. Cdc7 is required throughout the yeast S phase to activate replication origins.

    PubMed

    Donaldson, A D; Fangman, W L; Brewer, B J

    1998-02-15

    The long-standing conclusion that the Cdc7 kinase of Saccharomyces cerevisiae is required only to trigger S phase has been challenged by recent data that suggests it acts directly on individual replication origins. We tested the possibility that early- and late-activated origins have different requirements for Cdc7 activity. Cells carrying a cdc7(ts) allele were first arrested in G1 at the cdc7 block by incubation at 37 degrees C, and then were allowed to enter S phase by brief incubation at 23 degrees C. During the S phase, after return to 37 degrees C, early-firing replication origins were activated, but late origins failed to fire. Similarly, a plasmid with a late-activated origin was defective in replication. As a consequence of the origin activation defect, duplication of chromosomal sequences that are normally replicated from late origins was greatly delayed. Early-replicating regions of the genome duplicated at approximately their normal time. The requirements of early and late origins for Cdc7 appear to be temporally rather than quantitatively different, as reducing overall levels of Cdc7 by growth at semi-permissive temperature reduced activation at early and late origins approximately equally. Our results show that Cdc7 activates early and late origins separately, with late origins requiring the activity later in S phase to permit replication initiation.

  18. Temporal Dynamics of Activation of Thematic and Functional Knowledge During Conceptual Processing of Manipulable Artifacts

    PubMed Central

    Kalénine, Solène; Mirman, Daniel; Middleton, Erica L.; Buxbaum, Laurel J.

    2012-01-01

    The current research aimed at specifying the activation time course of different types of semantic information during object conceptual processing and the effect of context on this time course. We distinguished between thematic and functional knowledge and the specificity of functional similarity. Two experiments were conducted with healthy older adults using eye tracking in a word-to-picture matching task. The time course of gaze fixations was used to assess activation of distractor objects during the identification of manipulable artifact targets (e.g., broom). Distractors were (a) thematically related (e.g., dustpan), (b) related by a specific function (e.g., vacuum cleaner), or (c) related by a general function (e.g., sponge). Growth curve analyses were used to assess competition effects when target words were presented in isolation (Experiment 1) and embedded in contextual sentences of different generality levels (Experiment 2). In the absence of context, there was earlier and shorter lasting activation of thematically related as compared to functionally related objects. The time course difference was more pronounced for general functions than specific functions. When contexts were provided, functional similarities that were congruent with context generality level increased in salience with earlier activation of those objects. Context had little impact on thematic activation time course. These data demonstrate that processing a single manipulable artifact concept implicitly activates thematic and functional knowledge with different time courses and that context speeds activation of context-congruent functional similarity. PMID:22449134

  19. Talin-dependent integrin activation is required for fibrin clot retraction by platelets

    PubMed Central

    Haling, Jacob R.; Monkley, Susan J.; Critchley, David R.

    2011-01-01

    Talin functions both as a regulator of integrin affinity and as an important mechanical link between integrins and the cytoskeleton. Using genetic deletion of talin, we show for the first time that the capacity of talin to activate integrins is required for fibrin clot retraction by platelets. To further dissect which talin functions are required for this process, we tested clot retraction in platelets expressing a talin1(L325R) mutant that binds to integrins, but exhibits impaired integrin activation ascribable to disruption of the interaction between talin and the membrane-proximal region (MPR) in the β-integrin cytoplasmic domain. Talin-deficient and talin1(L325R) platelets were defective in retracting fibrin clots. However, the defect in clot retraction in talin1(L325R) platelets, but not talin-deficient platelets, was rescued by extrinsically activating integrins with manganese, thereby proving that integrin activation is required and showing that talin1(L325R) can form functional links to the actin cytoskeleton. PMID:20971947

  20. 24 CFR 1000.50 - What Indian preference requirements apply to IHBG administration activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false What Indian preference requirements apply to IHBG administration activities? 1000.50 Section 1000.50 Housing and Urban Development... § 1000.50 What Indian preference requirements apply to IHBG administration activities? To the greatest...

  1. Effectiveness of the Sport Education Fitness Model on Fitness Levels, Knowledge, and Physical Activity

    ERIC Educational Resources Information Center

    Pritchard, Tony; Hansen, Andrew; Scarboro, Shot; Melnic, Irina

    2015-01-01

    The purpose of this study was to investigate changes in fitness levels, content knowledge, physical activity levels, and participants' perceptions following the implementation of the sport education fitness model (SEFM) at a high school. Thirty-two high school students participated in 20 lessons using the SEFM. Aerobic capacity, muscular…

  2. Integration of Mathematical and Natural-Science Knowledge in School Students' Project-Based Activity

    ERIC Educational Resources Information Center

    Luneeva, Olga L.; Zakirova, Venera G.

    2017-01-01

    New educational standards implementation prioritizes the projective beginning of training in school education. Therefore, consideration of educational activity only as the process of obtaining ready knowledge should be abandoned. Thus the relevance of the studied problem is substantiated by the need to develop methodical works connected with the…

  3. Health-Related Fitness Knowledge and Its Relation to Student Physical Activity Patterns at a Large U.S. Southern State University

    ERIC Educational Resources Information Center

    Keating, Xiaofen D.; Castro-Pinero, Jose; Centeio, Erin; Harrison, Louis, Jr.; Ramirez, Tere; Chen, Li

    2010-01-01

    This study examined student health-related fitness (HRF) knowledge and its relationship to physical activity (PA). The participants were undergraduate students from a large U.S. state university. HRF knowledge was assessed using a test consisting of 150 multiple choice items. Differences in HRF knowledge scores by sex, ethnicity, and years in…

  4. 49 CFR 383.117 - Requirements for passenger endorsement.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... COMMERCIAL DRIVER'S LICENSE STANDARDS; REQUIREMENTS AND PENALTIES Required Knowledge and Skills § 383.117... following additional knowledge and skills test requirements. (a) Knowledge test. All applicants for the... procedures not otherwise specified. (b) Skills test. To obtain a passenger endorsement applicable to a...

  5. Students' Knowledge Sources and Knowledge Sharing in the Design Studio--An Exploratory Study

    ERIC Educational Resources Information Center

    Chiu, Sheng-Hsiao

    2010-01-01

    Architectural design is a knowledge-intensive activity; however, students frequently lack sufficient knowledge when they practice design. Collaborative learning can supplement the students' insufficient expertise. Successful collaborative learning relies on knowledge sharing between students. This implies that the peers are a considerable design…

  6. 10 CFR 60.7 - License not required for certain preliminary activities.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false License not required for certain preliminary activities. 60.7 Section 60.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.7 License not required for certain preliminary...

  7. 10 CFR 60.7 - License not required for certain preliminary activities.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false License not required for certain preliminary activities. 60.7 Section 60.7 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES General Provisions § 60.7 License not required for certain preliminary...

  8. Transcriptional activation of peroxisome proliferator-activated receptor-{gamma} requires activation of both protein kinase A and Akt during adipocyte differentiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Sang-pil; Ha, Jung Min; Yun, Sung Ji

    2010-08-13

    Research highlights: {yields} Elevated cAMP activates both PKA and Epac. {yields} PKA activates CREB transcriptional factor and Epac activates PI3K/Akt pathway via Rap1. {yields} Akt modulates PPAR-{gamma} transcriptional activity in concert with CREB. -- Abstract: Peroxisome proliferator-activated receptor-{gamma} (PPAR-{gamma}) is required for the conversion of pre-adipocytes. However, the mechanism underlying activation of PPAR-{gamma} is unclear. Here we showed that cAMP-induced activation of protein kinase A (PKA) and Akt is essential for the transcriptional activation of PPAR-{gamma}. Hormonal induction of adipogenesis was blocked by a phosphatidylinositol 3-kinase (PI3K) inhibitor (LY294002), by a protein kinase A (PKA) inhibitor (H89), and by amore » Rap1 inhibitor (GGTI-298). Transcriptional activity of PPAR-{gamma} was markedly enhanced by 3-isobutyl-1-methylxanthine (IBMX), but not insulin and dexamethasone. In addition, IBMX-induced PPAR-{gamma} transcriptional activity was blocked by PI3K/Akt, PKA, or Rap1 inhibitors. 8-(4-Chlorophenylthio)-2'-O-methyl-cAMP (8-pCPT-2'-O-Me-cAMP) which is a specific agonist for exchanger protein directly activated by cAMP (Epac) significantly induced the activation of Akt. Furthermore, knock-down of Akt1 markedly attenuated PPAR-{gamma} transcriptional activity. These results indicate that both PKA and Akt signaling pathways are required for transcriptional activation of PPAR-{gamma}, suggesting post-translational activation of PPAR-{gamma} might be critical step for adipogenic gene expression.« less

  9. Social construction of physical knowledge of shadows: A study of five preoperational children's perceptions, collaborative experiences, and activities across knowledge domains

    NASA Astrophysics Data System (ADS)

    Smith, Amy M.

    The first purpose of this qualitative case study was to understand the process of social construction of physical knowledge of shadows among preoperational thinkers by examining collaborative behaviors that may lead to new knowledge. The second purpose was to understand children's perspectives concerning the connection between social interaction and learning. The study focused on group collaboration and physical knowledge building as they relate to preoperational thought, a phase of cognitive development in early childhood. The case study consisted of five kindergarten children enrolled in a private, laboratory school at a southern, urban university. Across the eight-week data collection period, the children explored shadows through planned activities on 10 occasions and were interviewed three times in a focus group context. Primary methods for collecting data included videotaping the interviews and participant observations. Data were transcribed and coded inductively to discover emerging patterns while relating these patterns to existing constructivist theories. In addition, field notes, artifacts, and interviews with the children's teacher served to verify the findings. The findings revealed four major themes. Firstly, in terms of collaborative learning, children, while exhibiting a focus on the self, were attracted to learning with each other. Secondly, interactions seldom involved dialogic complexity, revealing minimal rationale, even during conflict. Thirdly, negative behaviors, such as tattling and exclusion, and prosocial behaviors, such as helping, were perceived as integral to the success of social construction of knowledge. The children considered each of these moral behaviors from the personal standpoint of how it affected them emotionally and in accomplishing a learning-related task. Fourthly, in terms of knowledge building, the findings indicated children's knowledge of shadows evolved over time as they participated in a developing scientific community

  10. Diagnosis: Reasoning from first principles and experiential knowledge

    NASA Technical Reports Server (NTRS)

    Williams, Linda J. F.; Lawler, Dennis G.

    1987-01-01

    Completeness, efficiency and autonomy are requirements for suture diagnostic reasoning systems. Methods for automating diagnostic reasoning systems include diagnosis from first principles (i.e., reasoning from a thorough description of structure and behavior) and diagnosis from experiential knowledge (i.e., reasoning from a set of examples obtained from experts). However, implementation of either as a single reasoning method fails to meet these requirements. The approach of combining reasoning from first principles and reasoning from experiential knowledge does address the requirements discussed above and can possibly ease some of the difficulties associated with knowledge acquisition by allowing developers to systematically enumerate a portion of the knowledge necessary to build the diagnosis program. The ability to enumerate knowledge systematically facilitates defining the program's scope, completeness, and competence and assists in bounding, controlling, and guiding the knowledge acquisition process.

  11. Knowledge Management

    NASA Technical Reports Server (NTRS)

    Shariq, Syed Z.; Kutler, Paul (Technical Monitor)

    1997-01-01

    The emergence of rapidly expanding technologies for distribution and dissemination of information and knowledge has brought to focus the opportunities for development of knowledge-based networks, knowledge dissemination and knowledge management technologies and their potential applications for enhancing productivity of knowledge work. The challenging and complex problems of the future can be best addressed by developing the knowledge management as a new discipline based on an integrative synthesis of hard and soft sciences. A knowledge management professional society can provide a framework for catalyzing the development of proposed synthesis as well as serve as a focal point for coordination of professional activities in the strategic areas of education, research and technology development. Preliminary concepts for the development of the knowledge management discipline and the professional society are explored. Within this context of knowledge management discipline and the professional society, potential opportunities for application of information technologies for more effectively delivering or transferring information and knowledge (i.e., resulting from the NASA's Mission to Planet Earth) for the development of policy options in critical areas of national and global importance (i.e., policy decisions in economic and environmental areas) can be explored, particularly for those policy areas where a global collaborative knowledge network is likely to be critical to the acceptance of the policies.

  12. Towards transdisciplinarity in Arctic sustainability knowledge co-production: Socially-Oriented Observations as a participatory integrated activity

    NASA Astrophysics Data System (ADS)

    Vlasova, Tatiana; Volkov, Sergey

    2016-09-01

    The paper is an attempt to tie together main biogeophysical and social science projects under the auspice of interdisciplinary sustainability science development. Special attention is put to the necessity of the transdisciplinary knowledge co-production based on activities and problem-solutions approaches. It puts attention to the role of monitoring activities in sustainability interdisciplinary science and transdisciplinary knowledge evolution in the Arctic. Socially focused monitoring named Socially-Oriented Observations creating a transdisciplinary space is viewed as one of sources of learning and transformations towards sustainability making possible to shape rapid changes happening in the Arctic based on sustainability knowledge co-production. Continuous Socially-Oriented Observations integrating scientific, education and monitoring methods enables to define adaptation and transformation pathways in the Arctic - the most rapidly changing region of our planet. Socially-Oriented Observations are based on the existing and developing interdisciplinary scientific approaches emerged within natural science and social science projects, sustainable development and resilience concepts putting principle attention to building sustainable and resilient socio-ecological systems. It is argued that the Arctic sustainability science is a valuable component of the whole and broader system of the Arctic Sustainability knowledge co-produced with the help of transdisciplinary approaches integrating science, local/traditional knowledge, entrepreneurship, education, decision-making. Socially-Oriented Observations are designed to be a transdisciplinary interactive continuous participatory process empowering deliberate choices of people that can shape the changes and enable transformation towards sustainability. Approaches of Socially-Oriented Observations and methods of implementation that have been developed since the IPY 2007/2008 and being practiced in different regions of the

  13. Behaviors and Knowledge of Healthcorps New York City High School Students: Nutrition, Mental Health, and Physical Activity

    ERIC Educational Resources Information Center

    Heo, Moonseong; Irvin, Erica; Ostrovsky, Natania; Isasi, Carmen; Blank, Arthur E.; Lounsbury, David W.; Fredericks, Lynn; Yom, Tiana; Ginsberg, Mindy; Hayes, Shawn; Wylie-Rosett, Judith

    2016-01-01

    Background: HealthCorps provides school wellness programming using curricula to promote changes in nutrition, mental health, and physical activity behaviors. The research objective was to evaluate effects of implementing its curricula on nutrition, mental health, and physical activity knowledge and behavior. Methods: Pre- and postsurvey data were…

  14. Nutrition and physical activity randomized control trial in child care centers improves knowledge, policies, and children’s body mass index

    PubMed Central

    2014-01-01

    Background To address the public health crisis of overweight and obese preschool-age children, the Nutrition And Physical Activity Self Assessment for Child Care (NAP SACC) intervention was delivered by nurse child care health consultants with the objective of improving child care provider and parent nutrition and physical activity knowledge, center-level nutrition and physical activity policies and practices, and children’s body mass index (BMI). Methods A seven-month randomized control trial was conducted in 17 licensed child care centers serving predominantly low income families in California, Connecticut, and North Carolina, including 137 child care providers and 552 families with racially and ethnically diverse children three to five years old. The NAP SACC intervention included educational workshops for child care providers and parents on nutrition and physical activity and consultation visits provided by trained nurse child care health consultants. Demographic characteristics and pre - and post-workshop knowledge surveys were completed by providers and parents. Blinded research assistants reviewed each center’s written health and safety policies, observed nutrition and physical activity practices, and measured randomly selected children’s nutritional intake, physical activity, and height and weight pre- and post-intervention. Results Hierarchical linear models and multiple regression models assessed individual- and center-level changes in knowledge, policies, practices and age- and sex-specific standardized body mass index (zBMI), controlling for state, parent education, and poverty level. Results showed significant increases in providers’ and parents’ knowledge of nutrition and physical activity, center-level improvements in policies, and child-level changes in children’s zBMI based on 209 children in the intervention and control centers at both pre- and post-intervention time points. Conclusions The NAP SACC intervention, as delivered by

  15. Personal Knowledge Integrators

    ERIC Educational Resources Information Center

    White, David C.

    2013-01-01

    This paper discusses, in the context of personal learning environments, the need for Personal Knowledge Integrators--PKI's or Knowers. It first illustrates and establishes the need for Knowers with usage scenarios and people's requirements. It then describes the elements required to make a Knower which can exchange information with other Knowers,…

  16. The effect of an active shooter response intervention on hospital employees' response knowledge, perceived program usefulness, and perceived organizational preparedness.

    PubMed

    Landry, Gail; Zimbro, Kathie S; Morgan, Merri K; Maduro, Ralitsa S; Snyder, Tim; Sweeney, Nancy L

    2018-04-02

    Active shooter events occur frequently across the United States in a variety of locations, including health care facilities. Hospital health care worker response to an active shooter event may mean the difference in life or death for self or others. There is little research on how hospitals prepare nonmanagers to respond to active shooter events. We conducted a study to explore differences in knowledge, perceived organizational preparedness, and program utility following participation in an active shooter response program. Self-efficacy, personal characteristics, and professional characteristics were also explored. Program evaluation was conducted via a one-group pretest/posttest design. There was a significant increase in knowledge and perceived organizational preparedness postintervention. Trait-level self-efficacy did not have a significant effect on retained knowledge and perceived organizational preparedness. The current study is the first known to evaluate the efficacy of an active shooter response program for nonmanagers within an inpatient health care facility. Findings from this study may inform risk managers on how to educate employees on what to expect and how to react should an active shooter event occur. © 2018 American Society for Healthcare Risk Management of the American Hospital Association.

  17. Towards a standardised representation of a knowledge base for adverse drug event prevention.

    PubMed

    Koutkias, Vassilis; Lazou, Katerina; de Clercq, Paul; Maglaveras, Nicos

    2011-01-01

    Knowledge representation is an important part of knowledge engineering activities that is crucial for enabling knowledge sharing and reuse. In this regard, standardised formalisms and technologies play a significant role. Especially for the medical domain, where knowledge may be tacit, not articulated and highly diverse, the development and adoption of standardised knowledge representations is highly challenging and of outmost importance to achieve knowledge interoperability. To this end, this paper presents a research effort towards the standardised representation of a Knowledge Base (KB) encapsulating rule-based signals and procedures for Adverse Drug Event (ADE) prevention. The KB constitutes an integral part of Clinical Decision Support Systems (CDSSs) to be used at the point of care. The paper highlights the requirements at the domain of discourse with respect to knowledge representation, according to which GELLO (an HL7 and ANSI standard) has been adopted. Results of our prototype implementation are presented along with the advantages and the limitations introduced by the employed approach.

  18. "We Know but We Don't Really Know": Diet, Physical Activity and Cardiovascular Disease Prevention Knowledge and Beliefs Among Underserved Pregnant Women.

    PubMed

    Beckham, A Jenna; Urrutia, Rachel Peragallo; Sahadeo, Latoya; Corbie-Smith, Giselle; Nicholson, Wanda

    2015-08-01

    To describe the knowledge of underserved pregnant women related to diet, physical activity, and cardiovascular disease (CVD). Underserved pregnant women from the University of North Carolina and Pitt County, North Carolina participated in 9 focus group interviews. Focus group questions focused on knowledge of CVD risk factors, lifestyle prevention strategies such as diet and physical activity, and the sources of such knowledge. Data were analyzed with the constant comparative method. Prior to the focus group, each woman was invited to complete a telephone survey to collect demographic information and responses to a 13-item CVD knowledge questionnaire. Means and frequency procedures were used to analyze demographic information. Fifty women participated in nine focus group interviews. Participants possessed basic knowledge of CVD risk factors and preventive strategies, such as basic guidelines and recommendations for healthy diet and physical activity in pregnancy. However, women often receive incomplete guidance from obstetric providers, and women, therefore, desired more information on these topics. Some gaps were filled by nurses and nutritionists. Women also sought information from female friends and relatives. Incorrect knowledge was demonstrated in all groups and led to less healthful behaviors in some cases. Underserved pregnant women have basic knowledge about healthy lifestyle and CVD prevention behaviors; however important gaps and misinformation exist.

  19. 10 CFR 73.50 - Requirements for physical protection of licensed activities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Requirements for physical protection of licensed activities. 73.50 Section 73.50 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PHYSICAL PROTECTION OF... suspicious activity or to the breaching of any physical barrier. (4) An isolation zone shall be maintained...

  20. A Controlled Experimental Evaluation of Three AIDS Prevention Activities for Improving Knowledge, Changing Attitudes, and Decreasing Risk Behaviors of High School Seniors.

    ERIC Educational Resources Information Center

    Smith, Mike U.; Katner, Harold P.

    This study was conducted to assess the level of AIDS-related knowledge, attitudes, and risk behaviors of a group of predominantly sexually active high school seniors (N=734) and to evaluate the relative effectiveness of three AIDS prevention activities in improving knowledge, attitudes, and behaviors among these students. The educational program…

  1. Attention Is Required for Knowledge-Based Sequential Grouping: Insights from the Integration of Syllables into Words.

    PubMed

    Ding, Nai; Pan, Xunyi; Luo, Cheng; Su, Naifei; Zhang, Wen; Zhang, Jianfeng

    2018-01-31

    How the brain groups sequential sensory events into chunks is a fundamental question in cognitive neuroscience. This study investigates whether top-down attention or specific tasks are required for the brain to apply lexical knowledge to group syllables into words. Neural responses tracking the syllabic and word rhythms of a rhythmic speech sequence were concurrently monitored using electroencephalography (EEG). The participants performed different tasks, attending to either the rhythmic speech sequence or a distractor, which was another speech stream or a nonlinguistic auditory/visual stimulus. Attention to speech, but not a lexical-meaning-related task, was required for reliable neural tracking of words, even when the distractor was a nonlinguistic stimulus presented cross-modally. Neural tracking of syllables, however, was reliably observed in all tested conditions. These results strongly suggest that neural encoding of individual auditory events (i.e., syllables) is automatic, while knowledge-based construction of temporal chunks (i.e., words) crucially relies on top-down attention. SIGNIFICANCE STATEMENT Why we cannot understand speech when not paying attention is an old question in psychology and cognitive neuroscience. Speech processing is a complex process that involves multiple stages, e.g., hearing and analyzing the speech sound, recognizing words, and combining words into phrases and sentences. The current study investigates which speech-processing stage is blocked when we do not listen carefully. We show that the brain can reliably encode syllables, basic units of speech sounds, even when we do not pay attention. Nevertheless, when distracted, the brain cannot group syllables into multisyllabic words, which are basic units for speech meaning. Therefore, the process of converting speech sound into meaning crucially relies on attention. Copyright © 2018 the authors 0270-6474/18/381178-11$15.00/0.

  2. The relationship between knowledge of leadership and knowledge management practices in the food industry in Kurdistan province, Iran.

    PubMed

    Jad, Seyyed Mohammad Moosavi; Geravandi, Sahar; Mohammadi, Mohammad Javad; Alizadeh, Rashin; Sarvarian, Mohammad; Rastegarimehr, Babak; Afkar, Abolhasan; Yari, Ahmad Reza; Momtazan, Mahboobeh; Valipour, Aliasghar; Mahboubi, Mohammad; Karimyan, Azimeh; Mazraehkar, Alireza; Nejad, Ali Soleimani; Mohammadi, Hafez

    2017-12-01

    The aim of this study was to identify the relationship between the knowledge of leadership and knowledge management practices. This research strategy, in terms of quantity, procedure and obtain information, is descriptive and correlational. Statistical population, consist of all employees of a food industry in Kurdistan province of Iran, who were engaged in 2016 and their total number is about 1800 people. 316 employees in the Kurdistan food industry (Kurdistan FI) were selected, using Cochran formula. Non-random method and valid questions (standard) for measurement of the data are used. Reliability and validity were confirmed. Statistical analysis of the data was carried out, using SPSS 16. The statistical analysis of collected data showed the relationship between knowledge-oriented of leadership and knowledge management activities as mediator variables. The results of the data and test hypotheses suggest that knowledge management activities play an important role in the functioning of product innovation and the results showed that the activities of Knowledge Management (knowledge transfer, storage knowledge, application of knowledge, creation of knowledge) on performance of product innovation.

  3. 76 FR 26750 - Agency Information Collection Activities: Documentation Requirements for Articles Entered Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-09

    ... Activities: Documentation Requirements for Articles Entered Under Various Special Tariff Treatment Provisions...: Documentation Requirements for Articles Entered Under Various Special Tariff Treatment Provisions. This request... collection: Title: Documentation Requirements for Articles Entered Under Various Special Tariff Treatment...

  4. 76 FR 39416 - Agency Information Collection Activities: Documentation Requirements for Articles Entered Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-06

    ... Activities: Documentation Requirements for Articles Entered Under Various Special Tariff Treatment Provisions... accordance with the Paperwork Reduction Act: Documentation Requirements for Articles Entered Under Various... techniques or other forms of information. Title: Documentation Requirements for Articles Entered Under...

  5. Developing pre-service science teachers' pedagogical content knowledge by using training program

    NASA Astrophysics Data System (ADS)

    Udomkan, Watinee; Suwannoi, Paisan

    2018-01-01

    A training program was developed for enhancing pre-service science teachers' pedagogical content knowledge (PCK). The pre-service science teachers are able to: understand science curriculum, knowledge of assessment in science, knowledge of students' understanding of science, instructional strategies and orientations towards science teaching, which is conceptualized as PCK [5]. This study examined the preservice science teachers' understandings and their practices which include five pre-service science teachers' PCK. In this study, the participants demonstrated their PCK through the process of the training program by writing content representations (CoRes), preparing the lesson plans, micro-teaching, and actual teaching respectively. All pre-service science teachers' performs were collected by classroom observations. Then, they were interviewed. The results showed that the pre-service science teachers progressively developed knowledge components of PCK. Micro-teaching is the key activities for developing PCK. However, they had some difficulties in their classroom teaching. They required of sufficient ability to design appropriate instructional strategies and assessment activities for teaching. Blending content and pedagogy is also a matter of great concern. The implication of this study was that science educators can enhance pre-service science teachers' PCK by fostering their better understandings of the instructional strategies, assessment activities and blending between content and pedagogy in their classroom.

  6. Maritime Activities: Requirements for Improving Space Based Solutions

    NASA Astrophysics Data System (ADS)

    Cragnolini, A.; Miguel-Lago, M.

    2005-03-01

    Maritime initiatives cannot be pursued only within their own perimeter. Sector endeavours and the policies which rule over them have wide range implications and several links with other sectors of activity. A well- balanced relationship of sea exploitation, maritime transportation, environmental protection and security ruled by national or international laws, will be a main issue for the future of all kind of maritime activities. Scientific research and technology development, along with enlightened and appropriate institutional regulations are relevant to ensure maritime sustainability.The use of satellite technology for monitoring international agreements should have a close co- ordination and be based on institutional consensus. Frequently, rules and new regulations set by policy makers are not demanding enough due to lack of knowledge about the possibilities offered by available technologies.Law enforcement actions could bring space technology new opportunities to offer solutions for monitoring and verification. Operators should aim at offering space data in a more operational and user-friendly way, providing them with useful and timely information.This paper will analyse the contribution of satellite technology to deal with the specificity of maritime sector, stressing the conditions for both an adequate technology improvement and an effective policy implementation.After analysing the links between maritime activities, space technologies and the institutional environment, the paper identifies some boundary conditions of the future developments. Conclusions are basically a check list for improving the present situation, while a road map is suggested as a matter of a way to proceed.

  7. An object-oriented, knowledge-based system for cardiovascular rehabilitation--phase II.

    PubMed Central

    Ryder, R. M.; Inamdar, B.

    1995-01-01

    The Heart Monitor is an object-oriented, knowledge-based system designed to support the clinical activities of cardiovascular (CV) rehabilitation. The original concept was developed as part of graduate research completed in 1992. This paper describes the second generation system which is being implemented in collaboration with a local heart rehabilitation program. The PC UNIX-based system supports an extensive patient database organized by clinical areas. In addition, a knowledge base is employed to monitor patient status. Rule-based automated reasoning is employed to assess risk factors contraindicative to exercise therapy and to monitor administrative and statutory requirements. PMID:8563285

  8. Dkk1 haploinsufficiency requires expression of Bmp2 for bone anabolic activity.

    PubMed

    Intini, Giuseppe; Nyman, Jeffry S

    2015-06-01

    Bone fractures remain a serious health burden and prevention and enhanced healing of fractures have been obtained by augmenting either BMP or Wnt signaling. However, whether BMP and Wnt signaling are both required or are self-sufficient for anabolic and fracture healing activities has never been fully elucidated. Mice haploinsufficient for Dkk1 (Dkk1(+/-)) exhibit a high bone mass phenotype due to an up-regulation of canonical Wnt signaling while mice lacking Bmp2 expression in the limbs (Bmp2(c/c);Prx1::cre) succumb to spontaneous fracture and are unable to initiate fracture healing; combined, these mice offer an opportunity to examine the requirement for activated BMP signaling on the anabolic and fracture healing activity of Wnts. When Dkk1(+/-) mice were crossed with Bmp2(c/c);Prx1::cre mice, the offspring bearing both genetic alterations were unable to increase bone mass and heal fractures, indicating that increased canonical Wnt signaling is unable to exploit its activity in absence of Bmp2. Thus, our data suggest that BMP signaling is required for Wnt-mediated anabolic activity and that therapies aimed at preventing fractures and fostering fracture repair may need to target both pathways for maximal efficacy. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Dkk1 haploinsufficiency requires expression of Bmp2 for bone anabolic activity

    PubMed Central

    Intini, Giuseppe; Nyman, Jeffry S.

    2015-01-01

    Bone fractures remain a serious health burden and prevention and enhanced healing of fractures has been obtained by augmenting either BMP or Wnt signaling. However, whether BMP and Wnt signaling are both required or are self-sufficient for anabolic and fracture healing activities has never been fully elucidated. Mice haploinsufficient for Dkk1 (Dkk1+/−) exhibit a high bone mass phenotype due to an up-regulation of canonical Wnt signaling while mice lacking Bmp2 expression in the limbs (Bmp2c/c;Prx1::cre) succumb to spontaneous fracture and are unable to initiate fracture healing; combined, these mice offer an opportunity to examine the requirement for activated BMP signaling on the anabolic and fracture healing activity of Wnts. When Dkk1+/− mice were crossed with Bmp2c/c;Prx1::cre mice, the offspring bearing both genetic alterations were unable to increase bone mass and heal fractures, indicating that increased canonical Wnt signaling is unable to exploit its activity in absence of Bmp2. Thus, our data suggest that BMP signaling is required for Wnt-mediated anabolic activity and that therapies aimed at preventing fractures and fostering fracture repair may need to target both pathways for maximal efficacy. PMID:25603465

  10. Combination of a Flipped Classroom Format and a Virtual Patient Case to Enhance Active Learning in a Required Therapeutics Course.

    PubMed

    Lichvar, Alicia Beth; Hedges, Ashley; Benedict, Neal J; Donihi, Amy C

    2016-12-25

    Objective. To design and evaluate the integration of a virtual patient activity in a required therapeutics course already using a flipped-classroom teaching format. Design. A narrative-branched, dynamic virtual-patient case was designed to replace the static written cases that students worked through during the class, which was dedicated to teaching the complications of liver disease. Students completed pre- and posttests before and after completing the virtual patient case. Examination scores were compared to those in the previous year. Assessment. Students' posttest scores were higher compared to pretest scores (33% vs 50%). Overall median examination scores were higher compared to the historical control group (70% vs 80%), as well as scores on questions assessing higher-level learning (67% vs 83%). A majority of students (68%) felt the virtual patient helped them apply knowledge gained in the pre-class video lecture. Students preferred this strategy to usual in-class activities (33%) or indicated it was of equal value (37%). Conclusion. The combination of a pre-class video lecture with an in-class virtual patient case is an effective active-learning strategy.

  11. Combination of a Flipped Classroom Format and a Virtual Patient Case to Enhance Active Learning in a Required Therapeutics Course

    PubMed Central

    Lichvar, Alicia Beth; Hedges, Ashley; Benedict, Neal J.

    2016-01-01

    Objective. To design and evaluate the integration of a virtual patient activity in a required therapeutics course already using a flipped-classroom teaching format. Design. A narrative-branched, dynamic virtual-patient case was designed to replace the static written cases that students worked through during the class, which was dedicated to teaching the complications of liver disease. Students completed pre- and posttests before and after completing the virtual patient case. Examination scores were compared to those in the previous year. Assessment. Students’ posttest scores were higher compared to pretest scores (33% vs 50%). Overall median examination scores were higher compared to the historical control group (70% vs 80%), as well as scores on questions assessing higher-level learning (67% vs 83%). A majority of students (68%) felt the virtual patient helped them apply knowledge gained in the pre-class video lecture. Students preferred this strategy to usual in-class activities (33%) or indicated it was of equal value (37%). Conclusion. The combination of a pre-class video lecture with an in-class virtual patient case is an effective active-learning strategy. PMID:28179724

  12. Knowledge exchange systems for youth health and chronic disease prevention: a tri-provincial case study.

    PubMed

    Murnaghan, D; Morrison, W; Griffith, E J; Bell, B L; Duffley, L A; McGarry, K; Manske, S

    2013-09-01

    The research teams undertook a case study design using a common analytical framework to investigate three provincial (Prince Edward Island, New Brunswick and Manitoba) knowledge exchange systems. These three knowledge exchange systems seek to generate and enhance the use of evidence in policy development, program planning and evaluation to improve youth health and chronic disease prevention. We applied a case study design to explore the lessons learned, that is, key conditions or processes contributing to the development of knowledge exchange capacity, using a multi-data collection method to gain an in-depth understanding. Data management, synthesis and analysis activities were concurrent, iterative and ongoing. The lessons learned were organized into seven "clusters." Key findings demonstrated that knowledge exchange is a complex process requiring champions, collaborative partnerships, regional readiness and the adaptation of knowledge exchange to diverse stakeholders. Overall, knowledge exchange systems can increase the capacity to exchange and use evidence by moving beyond collecting and reporting data. Areas of influence included development of new partnerships, expanded knowledge-sharing activities, and refinement of policy and practice approaches related to youth health and chronic disease prevention.

  13. 76 FR 69204 - Anti-Money Laundering Program and Suspicious Activity Reporting Requirements for Housing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-08

    ... 1506-AB14 Anti-Money Laundering Program and Suspicious Activity Reporting Requirements for Housing... enterprises as financial institutions for the purpose of requiring them to establish anti-money laundering... organizations to establish anti-money laundering programs and report suspicious activities is intended to help...

  14. Team- and Case-Based Learning to Activate Participants and Enhance Knowledge: An Evaluation of Seminars in Germany

    ERIC Educational Resources Information Center

    Kuhne-Eversmann, Lisa; Eversmann, Thomas; Fischer, Martin R.

    2008-01-01

    Introduction: There is a strong need for high-quality continuing medical education (CME) in Germany. To maintain a medical license, physicians are required to participate in regular training. Although evidence suggests that compared to lectures interactive methods can impart sustainable knowledge and a high degree of satisfaction, few interactive…

  15. Pharmaceutical knowledge governance: a human rights perspective.

    PubMed

    Lemmens, Trudo

    2013-01-01

    Industry control over the production and distribution of pharmaceutical safety and efficacy data has become a serious public health and health care funding concern. Various recent scandals, several involving the use of flawed representations of scientific data in the most influential medical journals, highlight the urgency of enhancing pharmaceutical knowledge governance. This paper analyzes why this is a human rights concern and what difference a human rights analysis can make. The paper first identifies the challenges associated with the current knowledge deficit. It then discusses, based on an analysis of case law, how various human rights associated interests can be invoked to support the claim that states have an obligation to actively contribute to independent knowledge governance, for example through ensuring clinical trials transparency. The paper further discusses a conceptual use of human rights, as a methodology which requires a comprehensive analysis of the different interwoven historical, economic, cultural, and social factors that contribute to the problem. Such an analysis reveals that historically grown drug regulations have, in fact, contributed directly to industry control over pharmaceutical knowledge production. This type of finding should inform needed reforms of drug regulation. The paper ends with a recommendation for a comprehensive global response to the problem of pharmaceutical knowledge governance. © 2013 American Society of Law, Medicine & Ethics, Inc.

  16. The Active Role of Instruments in Articulating Knowing and Knowledge: The Case of Animal Qualification Practices in Breeding Organisations

    ERIC Educational Resources Information Center

    Labatut, Julie; Aggeri, Franck; Astruc, Jean-Michel; Bibe, Bernard; Girard, Nathalie

    2009-01-01

    Purpose: The purpose of this paper is to investigate the role of instruments defined as artefacts, rules, models or norms, in the articulation between knowing-in-practice and knowledge, in learning processes. Design/methodology/approach: The paper focuses on a distributed, knowledge-intensive and instrumented activity at the core of any collective…

  17. A randomized controlled study to evaluate the effect of pharmacist-led educational intervention on glycemic control, self-care activities and disease knowledge among type 2 diabetes patients: A consort compliant study protocol.

    PubMed

    Bukhsh, Allah; Nawaz, Muhammad Sarfraz; Ahmed, Hafiz Sajjad; Khan, Tahir Mehmood

    2018-03-01

    Diabetes self-care activities, like, healthy diet, regular exercise, self-monitoring of blood glucose, and rational use of medicines are considered to play a vital role in establishing euglycemia. Health literacy among type 2 diabetes mellitus (T2DM) patients in Pakistan is very low, which is the most likely cause for poor clinical outcomes. This study is designed to investigate the impact of pharmacist-led educational intervention on glycemic control, self-care activities and disease knowledge among T2DM patients in Pakistan. In this randomized controlled trail, effectiveness of a 6-month pharmacist-led educational intervention will be examined on glycemic control, diabetes self-care activities and disease knowledge of 80 adult T2DM patients (age >30 years) with poorly controlled T2DM (HbA1c> 7%), after randomizing them into intervention and control groups, at diabetes care clinic of Capital Hospital Islamabad, Pakistan. The primary outcome is change in patients' HbA1c, whereas, changes in self-care activities and patients' disease knowledge are the secondary outcomes. After baseline assessment of their self-care activities and disease knowledge by using validated Urdu versions of Diabetes Self-management Questionnaire (DSMQ) and Diabetes Knowledge Questionnaire (DKQ), respectively, interventional group patients will be supplemented with a face-to-face pharmacist-led educational intervention, whereas, the control group will receive usual care. Intervention arm patients will be educated successively at their first follow-up visit (12th week) and telephonically after every 4 weeks. All assessments will be made at baseline and end of trail for both intervention and control groups. Multivariate general linear model will be applied to analyze the effects of the intervention. Glycemic control in T2DM patients requires optimum self-care activities. This study is an attempt to improve self-care behaviors among poorly controlled T2DM patients who are at higher risk of

  18. Photosensitization is required for antiretroviral activity of hypericin

    NASA Astrophysics Data System (ADS)

    Carpenter, Susan; Tossberg, John; Kraus, George A.

    1991-06-01

    In a seminal series of papers, Meruelo and co-workers have described the potent antiretroviral effect of hypericin. Interestingly, hypericin was found to inhibit not only the production of infectious virus from chronically infected cells, but was also shown to directly inhibit reverse transcriptase activity of mature virions. The effect of hypericin on cells chronically infected with equine infectious anemia virus (EIAV), a retrovirus genetically related to HIV, is demonstrated. At concentrations of 10 (mu) g/ml, hypericin reduced production of infectious EIAV by 99.99 without causing obvious cytopathic effects. Interestingly, the results indicated that the antiretroviral activity of hypericin was wholly dependent on the presence of light. No decrease in viral infectivity was observed when hypericin and virus were incubated in the dark. Moreover, it appeared that light was an absolute requirement for the antiviral activity, as even high concentrations of hypericin (10 (mu) g/ml) were unable to reduce infectivity of as few as 100 infectious virions.

  19. Human nicotine conditioning requires explicit contingency knowledge: is addictive behaviour cognitively mediated?

    PubMed

    Hogarth, Lee; Duka, Theodora

    2006-03-01

    Two seemingly contrary theories describe the learning mechanisms that mediate human addictive behaviour. According to the classical incentive theories of addiction, addictive behaviour is motivated by a Pavlovian conditioned appetitive emotional response elicited by drug-paired stimuli. Expectancy theory, on the other hand, argues that addictive behaviour is mediated by an expectancy of the drug imparted by cognitive knowledge of the Pavlovian (predictive) contingency between stimuli (S+) and the drug and of the instrumental (causal) contingency between instrumental behaviour and the drug. The present paper reviewed human-nicotine-conditioning studies to assess the role of appetitive emotional conditioning and explicit contingency knowledge in mediating addictive behaviour. The studies reviewed here provided evidence for both the emotional conditioning and the expectancy accounts. The first source of evidence is that nicotine-paired S+ elicit an appetitive emotional conditioned response (CR), albeit only in participants who expect nicotine. Furthermore, the magnitude of this emotional state is modulated by nicotine deprivation/satiation. However, the causal status of the emotional response in driving other forms of conditioned behaviour remains undemonstrated. The second source of evidence is that other nicotine CRs, including physiological responses, self-administration, attentional bias and subjective craving, are also dependent on participants possessing explicit knowledge of the Pavlovian contingencies arranged in the experiment. In addition, several of the nicotine CRs can be brought about or modified by instructed contingency knowledge, demonstrating the causal status of this knowledge. Collectively, these data suggest that human nicotine conditioned effects are mediated by an explicit expectancy of the drug coupled with an appetitive emotional response that reflects the positive biological value of the drug. The implication of this conclusion is that

  20. Examining Challenges Related to the Production of Actionable Climate Knowledge for Adaptation Decision-Making: A Focus on Climate Knowledge System Producers

    NASA Astrophysics Data System (ADS)

    Ernst, K.; Preston, B. L.; Tenggren, S.; Klein, R.; Gerger-Swartling, Å.

    2017-12-01

    Many challenges to adaptation decision-making and action have been identified across peer-reviewed and gray literature. These challenges have primarily focused on the use of climate knowledge for adaptation decision-making, the process of adaptation decision-making, and the needs of the decision-maker. Studies on climate change knowledge systems often discuss the imperative role of climate knowledge producers in adaptation decision-making processes and stress the need for producers to engage in knowledge co-production activities and to more effectively meet decision-maker needs. While the influence of climate knowledge producers on the co-production of science for adaptation decision-making is well-recognized, hardly any research has taken a direct approach to analyzing the challenges that climate knowledge producers face when undertaking science co-production. Those challenges can influence the process of knowledge production and may hinder the creation, utilization, and dissemination of actionable knowledge for adaptation decision-making. This study involves semi-structured interviews, focus groups, and participant observations to analyze, identify, and contextualize the challenges that climate knowledge producers in Sweden face as they endeavor to create effective climate knowledge systems for multiple contexts, scales, and levels across the European Union. Preliminary findings identify complex challenges related to education, training, and support; motivation, willingness, and culture; varying levels of prioritization; professional roles and responsibilities; the type and amount of resources available; and professional incentive structures. These challenges exist at varying scales and levels across individuals, organizations, networks, institutions, and disciplines. This study suggests that the creation of actionable knowledge for adaptation decision-making is not supported across scales and levels in the climate knowledge production landscape. Additionally

  1. Obstetric care providers' knowledge, practice and associated factors towards active management of third stage of labor in Sidama Zone, South Ethiopia.

    PubMed

    Tenaw, Zelalem; Yohannes, Zemenu; Amano, Abdela

    2017-09-07

    Active management of third stage of labor played a great role to prevent child birth related hemorrhage. However, maternal morbidity and mortality related to hemorrhage is high due to lack of knowledge and skill of obstetric care providers 'on active management of third stage of labor. Our study was aimed to assess knowledge, practice and associated factors of obstetric care providers (Midwives, Nurses and Health officers) on active management of third stage of labor in Sidama Zone, South Ethiopia. An institution based cross sectional study design was conducted from December 1-30 /2015 among midwives, nurses and health officers. Simple random sampling technique was used to get the total of 528 participants. Data entry was done using EPI Info 3.5.1 and exported to SPSS version 20.0 software package for analysis. The presence of association between independent and dependent variables was assessed using odds ratio with 97% confidence interval by applying logistic regression model. Of the 528 obstetric care providers 37.7% and 32.8% were knowledgeable and skilled to manage third stage of labor respectively. After controlling for possible confounding factors, the result showed that pre/in service training, being midwife and graduation year were found to be the major predictors of proper active management of third stage of labor. The knowledge and practice of obstetric care providers towards active management of third stage of labor can be improved with appropriate interventions like in-service trainings. This study also clearly showed that the level of knowledge and practice of obstetric care providers to wards active management of third stage of labor needs immediate attention of Universities and health science colleges better to revise their obstetrics course contents, health institutions and zonal health bureau should arrange trainings for their obstetrics care providers to enhance skill.

  2. RNA helicase A is not required for RISC activity.

    PubMed

    Liang, Xue-Hai; Crooke, Stanley T

    2013-10-01

    It has been shown that siRNAs can compete with each other or with endogenous miRNAs for RISC components. This competition may complicate the interpretations of phenotypes observed through siRNA-mediated knockdown of genes, especially those genes implicated in the RISC pathway. In this study, we re-examined the function of RNA helicase A (RHA), which has been previously proposed to function in RISC loading based on siRNA-mediated knockdown studies. Here we show that reduced RISC activity or loading of siRNAs was observed only in cells depleted of RHA using siRNA, but not using RNaseH-dependent antisense oligonucleotides (ASOs), suggesting that the impaired RISC function stems from the competition between pre-existing and newly transfected siRNAs, but not from reduction of the RHA protein. This view is further supported by the findings that cells depleted of a control protein, NCL1, using siRNA, but not ASO, exhibited similar defects on the loading and activity of a subsequently transfected siRNA. Transfection of RHA or NCL1 siRNAs, but not ASOs, reduced the levels of endogenous miRNAs, suggesting a competition mechanism. As a positive control, we showed that reduction of MOV10 by either siRNA or ASO decreased siRNA activity, confirming its role in RISC function. Together, our results indicate that RHA is not required for RISC activity or loading, and suggest that proper controls are required when using siRNAs to functionalize genes to avoid competition effects. © 2013. Published by Elsevier B.V. All rights reserved.

  3. PKC-Dependent Human Monocyte Adhesion Requires AMPK and Syk Activation

    PubMed Central

    Chang, Mei-Ying; Huang, Duen-Yi; Ho, Feng-Ming; Huang, Kuo-Chin; Lin, Wan-Wan

    2012-01-01

    PKC plays a pivotal role in mediating monocyte adhesion; however, the underlying mechanisms of PKC-mediated cell adhesion are still unclear. In this study, we elucidated the signaling network of phorbol ester PMA-stimulated human monocyte adhesion. Our results with pharmacological inhibitors suggested the involvement of AMPK, Syk, Src and ERK in PKC-dependent adhesion of THP-1 monocytes to culture plates. Biochemical analysis further confirmed the ability of PMA to activate these kinases, as well as the involvement of AMPK-Syk-Src signaling in this event. Direct protein interaction between AMPK and Syk, which requires the kinase domain of AMPK and linker region of Syk, was observed following PMA stimulation. Notably, we identified Syk as a novel downstream target of AMPK; AICAR can induce Syk phosphorylation at Ser178 and activation of this kinase. However, activation of AMPK alone, either by stimulation with AICAR or by overexpression, is not sufficient to induce monocyte adhesion. Studies further demonstrated that PKC-mediated ERK signaling independent of AMPK activation is also involved in cell adhesion. Moreover, AMPK, Syk, Src and ERK signaling were also required for PMA to induce THP-1 cell adhesion to endothelial cells as well as to induce adhesion response of human primary monocytes. Taken together, we propose a bifurcated kinase signaling pathway involved in PMA-mediated adhesion of monocytes. PKC can activate LKB1/AMPK, leading to phosphorylation and activation of Syk, and subsequent activation of Src and FAK. In addition, PKC-dependent ERK activation induces a coordinated signal for cytoskeleton rearrangement and cell adhesion. For the first time we demonstrate Syk as a novel substrate target of AMPK, and shed new light on the role of AMPK in monocyte adhesion, in addition to its well identified functions in energy homeostasis. PMID:22848421

  4. Integrating Social Activity Theory and Critical Discourse Analysis: A Multilayered Methodological Model for Examining Knowledge Mediation in Mentoring

    ERIC Educational Resources Information Center

    Becher, Ayelet; Orland-Barak, Lily

    2016-01-01

    This study suggests an integrative qualitative methodological framework for capturing complexity in mentoring activity. Specifically, the model examines how historical developments of a discipline direct mentors' mediation of professional knowledge through the language that they use. The model integrates social activity theory and a framework of…

  5. Active Learning Applications in the History of Chemistry: Pre-Service Chemistry Teachers' Level of Knowledge and Views

    ERIC Educational Resources Information Center

    Sendur, Gülten; Polat, Merve; Toku, Abdullah; Kazanci, Coskun

    2014-01-01

    This study aims to investigate the effects of a History and Philosophy of Chemistry-I course based on active learning applications on the level of knowledge of pre-service chemistry teachers about the history of chemistry. The views of pre-service chemistry teachers about these activities were also investigated. The study was carried out with 38…

  6. Engineering Knowledge for Assistive Living

    NASA Astrophysics Data System (ADS)

    Chen, Liming; Nugent, Chris

    This paper introduces a knowledge based approach to assistive living in smart homes. It proposes a system architecture that makes use of knowledge in the lifecycle of assistive living. The paper describes ontology based knowledge engineering practices and discusses mechanisms for exploiting knowledge for activity recognition and assistance. It presents system implementation and experiments, and discusses initial results.

  7. Differentiating Knowledge, Differentiating (Occupational) Practice

    ERIC Educational Resources Information Center

    Hordern, Jim

    2016-01-01

    This paper extends arguments for differentiating knowledge into conceptualisations of occupational practice. It is argued that specialised forms of knowledge and practice require recognition and differentiation in ways that many contemporary approaches to practice theory deny. Drawing on Hager's interpretation of MacIntyre, it is suggested that…

  8. Lecturers' Perception of Research Activities for Knowledge Production in Universities in Cross River State, Nigeria

    ERIC Educational Resources Information Center

    Uchendu, C. C.; Osim, R. O.; Odigwe, F. N.; Alade, F. N.

    2014-01-01

    This study examined lecturers' perception of research activities for knowledge production in universities in Cross River State, Nigeria. Two hypotheses were isolated to give direction to this investigation. 240 university lecturers were sampled from a population of 1,868 from the two universities in Cross River State, using stratified random…

  9. Towards a Methodology for Identifying Program Constraints During Requirements Analysis

    NASA Technical Reports Server (NTRS)

    Romo, Lilly; Gates, Ann Q.; Della-Piana, Connie Kubo

    1997-01-01

    Requirements analysis is the activity that involves determining the needs of the customer, identifying the services that the software system should provide and understanding the constraints on the solution. The result of this activity is a natural language document, typically referred to as the requirements definition document. Some of the problems that exist in defining requirements in large scale software projects includes synthesizing knowledge from various domain experts and communicating this information across multiple levels of personnel. One approach that addresses part of this problem is called context monitoring and involves identifying the properties of and relationships between objects that the system will manipulate. This paper examines several software development methodologies, discusses the support that each provide for eliciting such information from experts and specifying the information, and suggests refinements to these methodologies.

  10. Influence of a vertical subject on research in biomedicine and activities of The Cochrane Collaboration branch on medical students' knowledge and attitudes toward evidence-based medicine

    PubMed Central

    Balajić, Karolina; Barac-Latas, Vesna; Drenjančević, Ines; Ostojić, Marko; Fabijanić, Damir; Puljak, Livia

    2012-01-01

    Aim To investigate whether the introduction of a vertical subject on research in biomedicine and founding of The Cochrane Collaboration branch at the University of Split School of Medicine influenced students’ knowledge and attitudes toward evidence-based medicine (EBM), including the use of research literature. Methods We used a 26-item questionnaire on EBM knowledge and attitudes to survey 1232 medical students of all study years in 3 medical schools in Croatia (Split, Rijeka, Osijek) and the Croatian-speaking medical school in Mostar (Bosnia and Herzegovina). Results Students from the University of Split School of Medicine who had been exposed to the vertical subject on research in biomedicine and activities of The Cochrane Collaboration at the school had better knowledge and more positive attitudes toward EBM. In general, students rarely searched for evidence; 28% of students searched for evidence more than once a month and 96% of students used only textbooks in Croatian and teachers’ handouts, even though 74% of students agreed that articles from scholarly journals were an important supplement for textbooks. Conclusion Building up an environment that fosters EBM may be beneficial for students’ knowledge and attitudes toward EBM. Teachers should encourage and require using evidence during all the courses in medical school. PMID:22911530

  11. 25 CFR 262.4 - Activities by Indian tribes or individuals that require a permit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Activities by Indian tribes or individuals that require a... PRESERVATION PROTECTION OF ARCHAEOLOGICAL RESOURCES § 262.4 Activities by Indian tribes or individuals that require a permit. (a) No Indian tribe may, without a permit under the Act, excavate or remove...

  12. 20 CFR 404.1311 - Ninety-day active service requirement for World War II veterans.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... World War II veterans. 404.1311 Section 404.1311 Employees' Benefits SOCIAL SECURITY ADMINISTRATION... Uniformed Services World War II Veterans § 404.1311 Ninety-day active service requirement for World War II veterans. (a) The 90 days of active service required for World War II veterans do not have to be...

  13. Mitochondrial fragmentation in excitotoxicity requires ROCK activation.

    PubMed

    Martorell-Riera, Alejandro; Segarra-Mondejar, Marc; Reina, Manuel; Martínez-Estrada, Ofelia M; Soriano, Francesc X

    2015-01-01

    Mitochondria morphology constantly changes through fission and fusion processes that regulate mitochondrial function, and it therefore plays a prominent role in cellular homeostasis. Cell death progression is associated with mitochondrial fission. Fission is mediated by the mainly cytoplasmic Drp1, which is activated by different post-translational modifications and recruited to mitochondria to perform its function. Our research and other studies have shown that in the early moments of excitotoxic insult Drp1 must be nitrosylated to mediate mitochondrial fragmentation in neurons. Nonetheless, mitochondrial fission is a multistep process in which filamentous actin assembly/disassembly and myosin-mediated mitochondrial constriction play prominent roles. Here we establish that in addition to nitric oxide production, excitotoxicity-induced mitochondrial fragmentation also requires activation of the actomyosin regulator ROCK. Although ROCK1 has been shown to phosphorylate and activate Drp1, experiments using phosphor-mutant forms of Drp1 in primary cortical neurons indicate that in excitotoxic conditions, ROCK does not act directly on Drp1 to mediate fission, but may act on the actomyosin complex. Thus, these data indicate that a wider range of signaling pathways than those that target Drp1 are amenable to be inhibited to prevent mitochondrial fragmentation as therapeutic option.

  14. On-orbit Metrology and Calibration Requirements for Space Station Activities Definition Study

    NASA Technical Reports Server (NTRS)

    Cotty, G. M.; Ranganathan, B. N.; Sorrell, A. L.

    1989-01-01

    The Space Station is the focal point for the commercial development of space. The long term routine operation of the Space Station and the conduct of future commercial activities suggests the need for in-space metrology capabilities analogous when possible to those on-Earth. The ability to perform periodic calibrations and measurements with proper traceability is imperative for the routine operation of the Space Station. An initial review, however, indicated a paucity of data related to metrology and calibration requirements for in-space operations. This condition probably exists because of the highly developmental aspect of space activities to date, their short duration, and nonroutine nature. The on-orbit metrology and calibration needs of the Space Station were examined and assessed. In order to achieve this goal, the following tasks were performed: an up-to-date literature review; identification of on-orbit calibration techniques; identification of sensor calibration requirements; identification of calibration equipment requirements; definition of traceability requirements; preparation of technology development plans; and preparation of the final report. Significant information and major highlights pertaining to each task is presented. In addition, some general (generic) conclusions/observations and recommendations that are pertinent to the overall in-space metrology and calibration activities are presented.

  15. 76 FR 76430 - Agency Information Collection Activities: Documents Required Aboard Private Aircraft

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ... certificate of registration, which is also called a ``pink slip'' and is a duplicate copy of the Aircraft... Activities: Documents Required Aboard Private Aircraft AGENCY: U.S. Customs and Border Protection, Department... Required Aboard Private Aircraft. This is a proposed extension of an information collection that was...

  16. Modification of knowledge on occupational accidents among schoolchildren who resided in a landfill impacted area.

    PubMed

    Gomes, Rosangela Maiara Vindoura; Câmara, Volney de Magalhães; Souza, Delma Perpétua Oliveira de

    2016-01-01

    The prevalence of occupational accidents is very high in Brazil, having impacts on the health system and social security. This requires prevention, which must start with students of the Basic Education. The knowledge on this kind of accidents among children and adolescents studying in an area near a sanitary landfill was evaluated, before and after the development of activities on health education. A cross-sectional study was conducted in 2013 and included the application of the same questionnaire among students from a school in Cuiabá-MT, Brazil, before and after educational health activities related to the definition of occupational accidents. Univariate analyses of absolute and relative frequencies and bivariate analyses using the χ2 Test and Fisher's Exact Test were performed with a significance level of 0.05 and 95%CI. There was a statistically significant increase of the knowledge on these types of accidents after the educational activities (p < 0.05). The activities carried out indicate that schools are important for the development and systematization of knowledge arising from reality.

  17. Knowledge is power: how conceptual knowledge transforms visual cognition.

    PubMed

    Collins, Jessica A; Olson, Ingrid R

    2014-08-01

    In this review, we synthesize the existing literature demonstrating the dynamic interplay between conceptual knowledge and visual perceptual processing. We consider two theoretical frameworks that demonstrate interactions between processes and brain areas traditionally considered perceptual or conceptual. Specifically, we discuss categorical perception, in which visual objects are represented according to category membership, and highlight studies showing that category knowledge can penetrate early stages of visual analysis. We next discuss the embodied account of conceptual knowledge, which holds that concepts are instantiated in the same neural regions required for specific types of perception and action, and discuss the limitations of this framework. We additionally consider studies showing that gaining abstract semantic knowledge about objects and faces leads to behavioral and electrophysiological changes that are indicative of more efficient stimulus processing. Finally, we consider the role that perceiver goals and motivation may play in shaping the interaction between conceptual and perceptual processing. We hope to demonstrate how pervasive such interactions between motivation, conceptual knowledge, and perceptual processing are in our understanding of the visual environment, and to demonstrate the need for future research aimed at understanding how such interactions arise in the brain.

  18. Knowledge is Power: How Conceptual Knowledge Transforms Visual Cognition

    PubMed Central

    Collins, Jessica A.; Olson, Ingrid R.

    2014-01-01

    In this review we synthesize the existing literature demonstrating the dynamic interplay between conceptual knowledge and visual perceptual processing. We consider two theoretical frameworks demonstrating interactions between processes and brain areas traditionally considered perceptual or conceptual. Specifically, we discuss categorical perception, in which visual objects are represented according to category membership, and highlight studies showing that category knowledge can penetrate early stages of visual analysis. We next discuss the embodied account of conceptual knowledge, which holds that concepts are instantiated in the same neural regions required for specific types of perception and action, and discuss the limitations of this framework. We additionally consider studies showing that gaining abstract semantic knowledge about objects and faces leads to behavioral and electrophysiological changes that are indicative of more efficient stimulus processing. Finally, we consider the role that perceiver goals and motivation may play in shaping the interaction between conceptual and perceptual processing. We hope to demonstrate how pervasive such interactions between motivation, conceptual knowledge, and perceptual processing are to our understanding of the visual environment, and demonstrate the need for future research aimed at understanding how such interactions arise in the brain. PMID:24402731

  19. Software Requirements Analysis as Fault Predictor

    NASA Technical Reports Server (NTRS)

    Wallace, Dolores

    2003-01-01

    Waiting until the integration and system test phase to discover errors leads to more costly rework than resolving those same errors earlier in the lifecycle. Costs increase even more significantly once a software system has become operational. WE can assess the quality of system requirements, but do little to correlate this information either to system assurance activities or long-term reliability projections - both of which remain unclear and anecdotal. Extending earlier work on requirements accomplished by the ARM tool, measuring requirements quality information against code complexity and test data for the same system may be used to predict specific software modules containing high impact or deeply embedded faults now escaping in operational systems. Such knowledge would lead to more effective and efficient test programs. It may enable insight into whether a program should be maintained or started over.

  20. A Dyadic Approach to Understanding the Relationship of Maternal Knowledge of Youths' Activities to Youths' Problem Behavior among Rural Adolescents

    ERIC Educational Resources Information Center

    Lippold, Melissa A.; Greenberg, Mark T.; Feinberg, Mark E.

    2011-01-01

    Most studies that explore parental knowledge of youths' activities utilize parents' and youths' reports separately. Using a sample of 938 rural early adolescents (53% female; 84% White), we explore congruence between mothers' and youths' perceptions of maternal knowledge and its association with youth problem behaviors (delinquency, substance use,…

  1. Design of a Knowledge Driven HIS

    PubMed Central

    Pryor, T. Allan; Clayton, Paul D.; Haug, Peter J.; Wigertz, Ove

    1987-01-01

    Design of the software architecture for a knowledge driven HIS is presented. In our design the frame has been used as the basic unit of knowledge representation. The structure of the frame is being designed to be sufficiently universal to contain knowledge required to implement not only expert systems, but almost all traditional HIS functions including ADT, order entry and results review. The design incorporates a two level format for the knowledge. The first level as ASCII records is used to maintain the knowledge base while the second level converted by special knowledge compilers to standard computer languages is used for efficient implementation of the knowledge applications.

  2. A Knowledge-Based Arrangement of Prototypical Neural Representation Prior to Experience Contributes to Selectivity in Upcoming Knowledge Acquisition.

    PubMed

    Kurashige, Hiroki; Yamashita, Yuichi; Hanakawa, Takashi; Honda, Manabu

    2018-01-01

    Knowledge acquisition is a process in which one actively selects a piece of information from the environment and assimilates it with prior knowledge. However, little is known about the neural mechanism underlying selectivity in knowledge acquisition. Here we executed a 2-day human experiment to investigate the involvement of characteristic spontaneous activity resembling a so-called "preplay" in selectivity in sentence comprehension, an instance of knowledge acquisition. On day 1, we presented 10 sentences (prior sentences) that were difficult to understand on their own. On the following day, we first measured the resting-state functional magnetic resonance imaging (fMRI). Then, we administered a sentence comprehension task using 20 new sentences (posterior sentences). The posterior sentences were also difficult to understand on their own, but some could be associated with prior sentences to facilitate their understanding. Next, we measured the posterior sentence-induced fMRI to identify the neural representation. From the resting-state fMRI, we extracted the appearances of activity patterns similar to the neural representations for posterior sentences. Importantly, the resting-state fMRI was measured before giving the posterior sentences, and thus such appearances could be considered as preplay-like or prototypical neural representations. We compared the intensities of such appearances with the understanding of posterior sentences. This gave a positive correlation between these two variables, but only if posterior sentences were associated with prior sentences. Additional analysis showed the contribution of the entorhinal cortex, rather than the hippocampus, to the correlation. The present study suggests that prior knowledge-based arrangement of neural activity before an experience contributes to the active selection of information to be learned. Such arrangement prior to an experience resembles preplay activity observed in the rodent brain. In terms of knowledge

  3. "Heart Shots": a classroom activity to instigate active learning.

    PubMed

    Abraham, Reem Rachel; Vashe, Asha; Torke, Sharmila

    2015-09-01

    The present study aimed to provide undergraduate medical students at Melaka Manipal Medical College (Manipal Campus), Manipal University, in Karnataka, India, an opportunity to apply their knowledge in cardiovascular concepts to real-life situations. A group activity named "Heart Shots" was implemented for a batch of first-year undergraduate students (n = 105) at the end of a block (teaching unit). Students were divided into 10 groups each having 10-11 students. They were requested to make a video/PowerPoint presentation about the application of cardiovascular principles to real-life situations. The presentation was required to be of only pictures/photos and no text material, with a maximum duration of 7 min. More than 95% of students considered that the activity helped them to apply their knowledge in cardiovascular concepts to real-life situations and understand the relevance of physiology in medicine and to revise the topic. More than 90% of students agreed that the activity helped them to apply their creativity in improving their knowledge and to establish a link between concepts rather than learning them as isolated facts. Based on the feedback, we conclude that the activity was student centered and that it facilitated learning. Copyright © 2015 The American Physiological Society.

  4. Design knowledge capture for a corporate memory facility

    NASA Technical Reports Server (NTRS)

    Boose, John H.; Shema, David B.; Bradshaw, Jeffrey M.

    1990-01-01

    Currently, much of the information regarding decision alternatives and trade-offs made in the course of a major program development effort is not represented or retained in a way that permits computer-based reasoning over the life cycle of the program. The loss of this information results in problems in tracing design alternatives to requirements, in assessing the impact of change in requirements, and in configuration management. To address these problems, the problem was studied of building an intelligent, active corporate memory facility which would provide for the capture of the requirements and standards of a program, analyze the design alternatives and trade-offs made over the program's lifetime, and examine relationships between requirements and design trade-offs. Early phases of the work have concentrated on design knowledge capture for the Space Station Freedom. Tools are demonstrated and extended which helps automate and document engineering trade studies, and another tool is being developed to help designers interactively explore design alternatives and constraints.

  5. From Data to Knowledge: GEOSS experience and the GEOSS Knowledge Base contribution to the GCI

    NASA Astrophysics Data System (ADS)

    Santoro, M.; Nativi, S.; Mazzetti, P., Sr.; Plag, H. P.

    2016-12-01

    According to systems theory, data is raw, it simply exists and has no significance beyond its existence; while, information is data that has been given meaning by way of relational connection. The appropriate collection of information, such that it contributes to understanding, is a process of knowledge creation.The Global Earth Observation System of Systems (GEOSS) developed by the Group on Earth Observations (GEO) is a set of coordinated, independent Earth observation, information and processing systems that interact and provide access to diverse information for a broad range of users in both public and private sectors. GEOSS links these systems to strengthen the monitoring of the state of the Earth. In the past ten years, the development of GEOSS has taught several lessons dealing with the need to move from (open) data to information and knowledge sharing. Advanced user-focused services require to move from a data-driven framework to a knowledge sharing platform. Such a platform needs to manage information and knowledge, in addition to datasets linked to them. For this scope, GEO has launched a specific task called "GEOSS Knowledge Base", which deals with resources, like user requirements, Sustainable Development Goals (SDGs), observation and processing ontologies, publications, guidelines, best practices, business processes/algorithms, definition of advanced concepts like Essential Variables (EVs), indicators, strategic goals, etc. In turn, information and knowledge (e.g. guidelines, best practices, user requirements, business processes, algorithms, etc.) can be used to generate additional information and knowledge from shared datasets. To fully utilize and leverage the GEOSS Knowledge Base, the current GEOSS Common Infrastructure (GCI) model will be extended and advanced to consider important concepts and implementation artifacts, such as data processing services and environmental/economic models as well as EVs, Primary Indicators, and SDGs. The new GCI model

  6. Chief Knowledge Officers? Perceptions, Pitfalls, & Potential.

    ERIC Educational Resources Information Center

    Corcoran, Mary; Jones, Rebecca

    1997-01-01

    Argues that few librarians possess the needed competencies to fill the role of "chief knowledge officer" or "knowledge executive." Outlines executive competencies required: communications, leadership, experience, financial management, customer focus, entrepreneurial insight, and information technology grounding; examines gaps…

  7. Automatic knowledge extraction from chemical structures: the case of mutagenicity prediction.

    PubMed

    Ferrari, T; Cattaneo, D; Gini, G; Golbamaki Bakhtyari, N; Manganaro, A; Benfenati, E

    2013-01-01

    This work proposes a new structure-activity relationship (SAR) approach to mine molecular fragments that act as structural alerts for biological activity. The entire process is designed to fit with human reasoning, not only to make the predictions more reliable but also to permit clear control by the user in order to meet customized requirements. This approach has been tested on the mutagenicity endpoint, showing marked prediction skills and, more interestingly, bringing to the surface much of the knowledge already collected in the literature as well as new evidence.

  8. Factors Required for Activation of Urease as a Virulence Determinant in Cryptococcus neoformans

    PubMed Central

    Singh, Arpita; Panting, Robert J.; Varma, Ashok; Saijo, Tomomi; Waldron, Kevin J.; Jong, Ambrose; Ngamskulrungroj, Popchai; Chang, Yun C.; Rutherford, Julian C.; Kwon-Chung, Kyung J.

    2013-01-01

    ABSTRACT Urease in Cryptococcus neoformans plays an important role in fungal dissemination to the brain and causing meningoencephalitis. Although urea is not required for synthesis of apourease encoded by URE1, the available nitrogen source affected the expression of URE1 as well as the level of the enzyme activity. Activation of the apoenzyme requires three accessory proteins, Ure4, Ure6, and Ure7, which are homologs of the bacterial urease accessory proteins UreD, UreF, and UreG, respectively. A yeast two-hybrid assay showed positive interaction of Ure1 with the three accessory proteins encoded by URE4, URE6, and URE7. Metalloproteomic analysis of cryptococcal lysates using inductively coupled plasma mass spectrometry (ICP-MS) and a biochemical assay of urease activity showed that, as in many other organisms, urease is a metallocentric enzyme that requires nickel transported by Nic1 for its catalytic activity. The Ure7 accessory protein (bacterial UreG homolog) binds nickel likely via its conserved histidine-rich domain and appears to be responsible for the incorporation of Ni2+ into the apourease. Although the cryptococcal genome lacks the bacterial UreE homolog, Ure7 appears to combine the functions of bacterial UreE and UreG, thus making this pathogen more similar to that seen with the plant system. Brain invasion by the ure1, ure7, and nic1 mutant strains that lack urease activity was significantly less effective in a mouse model. This indicated that an activated urease and not the Ure1 protein was responsible for enhancement of brain invasion and that the factors required for urease activation in C. neoformans resemble those of plants more than those of bacteria. PMID:23653445

  9. The contribution of indigenous knowledge to disaster risk reduction activities in Zimbabwe: A big call to practitioners

    PubMed Central

    Munsaka, Edson

    2018-01-01

    This article examined the contribution of indigenous knowledge to disaster risk reduction activities in Zimbabwe. The current discourse underrates the use of indigenous knowledge of communities by practitioners when dealing with disasters’, as the knowledge is often viewed as outdated and primitive. This study, which was conducted in 2016, sought to examine this problem through analysing the potential contribution of indigenous knowledge as a useful disaster risk reduction intervention. Tsholotsho district in Matabeleland, North province of Zimbabwe, which frequently experiences perennial devastating floods, was used as a case study. Interviews and researcher observations were used to gather data from 40 research participants. The findings were that communities understand weather patterns and could predict imminent flooding after studying trees and clouds, and the behaviours of certain animal species. Local communities also use available local resources to put structural measures in place as part of disaster risk reduction interventions. Despite this important potential, the study found that the indigenous knowledge of disaster risk reduction of the communities is often shunned by practitioners. The practitioners claim that indigenous knowledge lacks documentation, it is not found in all generational classes, it is contextualised to particular communities and the knowledge cannot be scientifically validated. The study concluded that both local communities and disaster risk reduction practitioners can benefit from the indigenous knowledge of communities. This research has the potential to benefit communities, policymakers and disaster risk reduction practitioners.

  10. Engaging in Problem Posing Activities in a Dynamic Geometry Setting and the Development of Prospective Teachers' Mathematical Knowledge

    ERIC Educational Resources Information Center

    Lavy, Ilana; Shriki, Atara

    2010-01-01

    In the present study we explore changes in perceptions of our class of prospective mathematics teachers (PTs) regarding their mathematical knowledge. The PTs engaged in problem posing activities in geometry, using the "What If Not?" (WIN) strategy, as part of their work on computerized inquiry-based activities. Data received from the PTs'…

  11. Relationships between Health-Related Fitness Knowledge, Perceived Competence, Self- Determination, and Physical Activity Behaviors of High School Students

    ERIC Educational Resources Information Center

    Haslem, Liz; Wilkinson, Carol; Prusak, Keven A.; Christensen, William F.; Pennington, Todd

    2016-01-01

    The purpose of this study was (a) to test a hypothesized model of motivation within the context of conceptual physical education (CPE), and (b) to explore the strength and directionality of perceived competence for physical activity as a possible mediator for health-related fitness knowledge (HRFK) and physical activity behaviors. High school…

  12. Context memory formation requires activity-dependent protein degradation in the hippocampus.

    PubMed

    Cullen, Patrick K; Ferrara, Nicole C; Pullins, Shane E; Helmstetter, Fred J

    2017-11-01

    Numerous studies have indicated that the consolidation of contextual fear memories supported by an aversive outcome like footshock requires de novo protein synthesis as well as protein degradation mediated by the ubiquitin-proteasome system (UPS). Context memory formed in the absence of an aversive stimulus by simple exposure to a novel environment requires de novo protein synthesis in both the dorsal (dHPC) and ventral (vHPC) hippocampus. However, the role of UPS-mediated protein degradation in the consolidation of context memory in the absence of a strong aversive stimulus has not been investigated. In the present study, we used the context preexposure facilitation effect (CPFE) procedure, which allows for the dissociation of context learning from context-shock learning, to investigate the role of activity-dependent protein degradation in the dHPC and vHPC during the formation of a context memory. We report that blocking protein degradation with the proteasome inhibitor clasto-lactacystin β-lactone (βLac) or blocking protein synthesis with anisomycin (ANI) immediately after context preexposure significantly impaired context memory formation. Additionally, we examined 20S proteasome activity at different time points following context exposure and saw that the activity of proteasomes in the dHPC increases immediately after stimulus exposure while the vHPC exhibits a biphasic pattern of proteolytic activity. Taken together, these data suggest that the requirement of increased proteolysis during memory consolidation is not driven by processes triggered by the strong aversive outcome (i.e., shock) normally used to support fear conditioning. © 2017 Cullen et al.; Published by Cold Spring Harbor Laboratory Press.

  13. 77 FR 23490 - Agency Information Collection Activities: Country of Origin Marking Requirements for Containers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-19

    ... Activities: Country of Origin Marking Requirements for Containers or Holders AGENCY: U.S. Customs and Border... of Origin Marking Requirements for Containers or Holders. This is a proposed extension of an... Requirements for Containers or Holders. [[Page 23491

  14. Creation of University Wellness Program Healthy Eating and Active Lifestyle Supports: A Knowledge-to-Action Process.

    PubMed

    Joy, Phillip; Mann, Linda; Blotnicky, Karen

    2018-03-01

    With the burdens that preventable health conditions place on individuals, workplaces, and society, workplace wellness programs (WWP) are critical to ensuring employees have access to health promotion supports tailored to their work environments. Such programs are best guided by a knowledge-to-action (KTA) framework; a theoretically grounded, systematic process that considers the ongoing exchange of knowledge with employees to engage them in health behaviour change and to garner employers' support for the interventions. Therefore the purpose of this project was to develop, implement, and evaluate WWP healthy eating and active lifestyle supports at a university. A KTA process guided the consultations with employees and stakeholders that led to the development and implementation of a range of resource effective supports and the incorporation of wellness in the organization culture. A key support was the Wellness Passport that encouraged participation in scheduled WWP activities, as well as allowing for self-identified ones. Quality assurance assessments demonstrated a desire for a continuation of these WWP supports and activities. Dietitians, as health promotion leaders, can play key roles in the emerging field of WWPs. University dietetic and internship programs should consider adding WWP and KTA training components.

  15. Enhancing Knowledge Integration: An Information System Capstone Project

    ERIC Educational Resources Information Center

    Steiger, David M.

    2009-01-01

    This database project focuses on learning through knowledge integration; i.e., sharing and applying specialized (database) knowledge within a group, and combining it with other business knowledge to create new knowledge. Specifically, the Tiny Tots, Inc. project described below requires students to design, build, and instantiate a database system…

  16. Collaborative Robots and Knowledge Management - A Short Review

    NASA Astrophysics Data System (ADS)

    Mușat, Flaviu-Constantin; Mihu, Florin-Constantin

    2017-12-01

    Because the requirements of the customers are more and more high related to quality, quantity, delivery times at lowest costs possible, the industry had to come with automated solutions to improve these requirements. Starting from the automated lines developed by Ford and Toyota, we have now developed automated and self-sustained working lines, which is possible nowadays-using collaborative robots. By using the knowledge management system we can improve the development of the future of this kind of area of research. This paper shows the benefits and the smartness use of the robots that are performing the manipulation activities that increases the work place ergonomically and improve the interaction between human - machine in order to assist in parallel tasks and lowering the physically human efforts.

  17. Students' Perceptions of an Experiential Learning Activity Designed to Develop Knowledge of Food and Food Preparation Methods

    ERIC Educational Resources Information Center

    Leveritt, Michael; Ball, Lauren; Desbrow, Jane

    2013-01-01

    The aim of this study was to describe student learning after completing an experiential learning task that was designed to develop students' knowledge of food and food preparation methods. The task required students to follow a special diet and then complete a daily online journal entry about the experience for other students to read and review.…

  18. Computer-assisted knowledge acquisition for hypermedia systems

    NASA Technical Reports Server (NTRS)

    Steuck, Kurt

    1990-01-01

    The usage of procedural and declarative knowledge to set up the structure or 'web' of a hypermedia environment is described. An automated knowledge acquisition tool was developed that helps a knowledge engineer elicit and represent an expert's knowledge involved in performing procedural tasks. The tool represents both procedural and prerequisite, declarative knowledge that supports each activity performed by the expert. This knowledge is output and subsequently read by a hypertext scripting language to generate the link between blank, but labeled cards. Each step of the expert's activity and each piece of supporting declarative knowledge is set up as an empty node. An instructional developer can then enter detailed instructional material concerning each step and declarative knowledge into these empty nodes. Other research is also described that facilitates the translation of knowledge from one form into a form more readily useable by computerized systems.

  19. HIPAA: update on rule revisions and compliance requirements.

    PubMed

    Maddox, P J

    2002-01-01

    Due to the highly technical requirements for HIPAA compliance and the numerous administrative and clinical functions and processes involved, guidance from experts who are knowledgeable about systems design and use to secure private data is necessary. In health care organizations, this will require individuals who are knowledgeable about clinical processes and those who understand health information technology, security, and privacy to work together to establish an entity's compliance plans and revise operations and practices accordingly. As a precondition of designing such systems, it is essential that covered entities understand the HIPAA's statutory requirements and timeline for compliance. An organization's success in preparing for HIPAA will depend upon an active program of assessment, planning, and implementation. Compliance with security and privacy standards can be expected to increase costs initially. However, greater use of EDI is expected to reduce costs and enhance revenues in the long run if processes and systems are improved. NOTE: Special protection for psychotherapy notes holds them to a higher standard of protection. Notes used only by a psychotherapist are not intended to be shared with anyone and are not considered part of the medical record.

  20. 41 CFR 51-7.2 - Early involvement in private, State, and local activities requiring Federal approval.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... environment; (3) Consult with appropriate Federal, regional, State and local agencies and other potentially... private, State, and local activities requiring Federal approval. 51-7.2 Section 51-7.2 Public Contracts... involvement in private, State, and local activities requiring Federal approval. (a) 40 CFR 1501.2(d) requires...

  1. 41 CFR 51-7.2 - Early involvement in private, State, and local activities requiring Federal approval.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... environment; (3) Consult with appropriate Federal, regional, State and local agencies and other potentially... private, State, and local activities requiring Federal approval. 51-7.2 Section 51-7.2 Public Contracts... involvement in private, State, and local activities requiring Federal approval. (a) 40 CFR 1501.2(d) requires...

  2. Increase Productivity Through Knowledge Management

    NASA Astrophysics Data System (ADS)

    Gavrikova, N. A.; Dolgih, I. N.; Dyrina, E. N.

    2016-04-01

    Increase in competition level requires companies to improve the efficiency of work force use characterized by labor productivity. Professional knowledge of staff and its experience play the key role in it. The results of Extrusion Line operator’s working time analysis are performed in this article. The analysis revealed that the reasons of working time ineffective use connected with inadequate information exchange and knowledge management in the company. Authors suggest the way to solve this problem: the main sources of knowledge in engineering enterprise have been defined, the conditions of success and the stages of knowledge management control have been stated.

  3. Knowledge-based design of a biosensor to quantify localized ERK activation in living cells

    PubMed Central

    Kummer, Lutz; Hsu, Chia-Wen; Dagliyan, Onur; MacNevin, Christopher; Kaufholz, Melanie; Zimmermann, Bastian; Dokholyan, Nikolay V.; Hahn, Klaus M.; Plückthun, Andreas

    2014-01-01

    Summary Investigation of protein activation in living cells is fundamental to understand how proteins are influenced by the full complement of upstream regulators they experience. We describe here the generation of a biosensor based on the Designed Ankyrin Repeat Protein (DARPin) binding scaffold suited for intracellular applications. Combining selection and evolution from libraries, knowledge-based design and efficient and rapid testing of conjugate candidates, we created an ERK activity biosensor by derivatizing a DARPin specific for phosphorylated ERK (pERK) with a solvatochromic merocyanine dye (mero87), whose fluorescence increases upon pERK binding. The biosensor specifically responded to pERK2, recognized by its conformation, but not to non-phosphorylated ERK2 or other closely related mitogen-activated kinases tested. Activated endogenous ERK was visualized in mouse embryo fibroblasts incubated in 2% serum, revealing greater activation in the nucleus, perinuclear regions, and especially the nucleoli. Activity was greatly reduced by the MEK1/2 inhibitor U0126. The DARPin-based biosensor will serve as useful tool for studying biological functions of ERK in vitro and in vivo. PMID:23790495

  4. The Importance of Establishing and Maintaining Continuity of Knowledge during 21st Century Nuclear Fuel Cycle Activities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pickett, Chris A; Rowe, Nathan C; Younkin, James R

    2012-01-01

    During this century, the entire nuclear fuel cycle will expand and become increasingly more global, taxing both the resources and capabilities of the International Atomic Energy Agency (IAEA) to maintain an effective Continuity of Knowledge (CoK) and its ability to provide timely detection of diversion. Uranium that currently is mined and milled in one country will be converted, enriched, and fabricated into fuel for reactors in an expanding set of new countries. This expansion will make it harder to guarantee that regional activities stay regional and that diversion detection is timely unless new and sustainable tools are developed to improvemore » inspector effectiveness. To deal with this emerging reality, the IAEA must increase its use of unattended monitoring and employ new tools and methods that enhance CoK during all phases of the fuel cycle. This approach will help provide useful information to aid in detecting undeclared activities and create opportunities for timely and appropriate responses to events well before they enter phases of greater concern (e.g., enrichment). The systems that maintain CoK of safeguarded assets rely on containment and surveillance (C/S) technologies. The 21st century fuel cycle will require increased use of these technologies and systems, plus greater implementation of unattended systems that can securely collect data when inspectors are not present.« less

  5. Association of knowledge, preventive counseling and personal health behaviors on physical activity and consumption of fruits or vegetables in community health workers.

    PubMed

    Florindo, Alex A; Brownson, Ross C; Mielke, Gregore I; Gomes, Grace Ao; Parra, Diana C; Siqueira, Fernando V; Lobelo, Felipe; Simoes, Eduardo J; Ramos, Luiz R; Bracco, Mário M; Hallal, Pedro C

    2015-04-09

    There is evidence that if a health professional is active and has a healthy diet, he/she is more likely to advise patients about the benefits of physical activity and healthy eating The aims of this study were to: (1) describe the personal physical activity, consumption of fruits and vegetables behaviors and nutritional status of community health workers; (2) evaluate the association between knowledge, delivery of preventive counseling and personal behaviors among community health workers. This was a cross-sectional study conducted in a nationally sample of health professionals working in primary health care settings in Brazil in 2011. This survey was part of the second phase of the Guide for Useful Interventions for Activity in Brazil and Latin America project, and data were collected through telephone interviews of 269 community health workers from the Unified Health Care system of Brazil. We applied questionnaires about personal reported behaviors, knowledge and preventive counseling in physical activity and consumption of fruits and vegetables. We calculated the prevalence and associations between the variables with logistic regression. The proportion of community health workers that practiced 150 minutes per week of physical activity in leisure time or transportation was high (64.9%). Half of community health workers were overweight and only 26.2% reported consuming five portions/day of fruits or vegetables. Most community health workers reported counseling about physical activity for more than six months (59.7%), and most were not knowledgeable of the fruits and vegetables and physical activity recommendations. Meeting the fruits and vegetables recommendations was associated with correct knowledge (OR = 4.5; CI95% 1.03;19.7), with reporting 150 minutes or more of physical activity per week (OR = 2.0; CI95% 1.03;3.7) and with reporting physical activity in leisure time (OR = 2.0; CI95% 1.05;3.6). Regular physical activity counseling was associated

  6. Differing contributions of inferior prefrontal and anterior temporal cortex to concrete and abstract conceptual knowledge

    PubMed Central

    Hoffman, Paul; Binney, Richard J.; Lambon Ralph, Matthew A.

    2015-01-01

    Semantic cognition is underpinned by regions involved in representing conceptual knowledge and executive control areas that provide regulation of this information according to current task requirements. Using distortion-corrected fMRI, we investigated the contributions of these two systems to abstract and concrete word comprehension. We contrasted semantic decisions made either with coherent contextual support, which encouraged retrieval of a rich conceptual representation, or with irrelevant contextual information, which instead maximised demands on control processes. Inferior prefrontal cortex was activated more when decisions were made in the presence of irrelevant context, suggesting that this region is crucial for the semantic control functions required to select appropriate aspects of meaning in the face of competing information. It also exhibited greater activation for abstract words, which reflects the fact that abstract words tend to have variable, context-dependent meanings that place higher demands on control processes. In contrast, anterior temporal regions (ATL) were most active when decisions were made with the benefit of a coherent context, suggesting a representational role. There was a graded shift in concreteness effects in this region, with dorsolateral areas particularly active for abstract words and ventromedial areas preferentially activated by concrete words. This supports the idea that concrete concepts are closely associated with visual experience and abstract concepts with auditory-verbal information; and that sub-regions of the ATL display graded specialisation for these two types of knowledge. Between these two extremes, we identified significant activations for both word types in ventrolateral ATL. This area is known to be involved in representing knowledge for concrete concepts; here we established that it is also activated by abstract concepts. These results converge with data from rTMS and neuropsychological investigations in

  7. Differing contributions of inferior prefrontal and anterior temporal cortex to concrete and abstract conceptual knowledge.

    PubMed

    Hoffman, Paul; Binney, Richard J; Lambon Ralph, Matthew A

    2015-02-01

    Semantic cognition is underpinned by regions involved in representing conceptual knowledge and executive control areas that provide regulation of this information according to current task requirements. Using distortion-corrected fMRI, we investigated the contributions of these two systems to abstract and concrete word comprehension. We contrasted semantic decisions made either with coherent contextual support, which encouraged retrieval of a rich conceptual representation, or with irrelevant contextual information, which instead maximised demands on control processes. Inferior prefrontal cortex was activated more when decisions were made in the presence of irrelevant context, suggesting that this region is crucial for the semantic control functions required to select appropriate aspects of meaning in the face of competing information. It also exhibited greater activation for abstract words, which reflects the fact that abstract words tend to have variable, context-dependent meanings that place higher demands on control processes. In contrast, anterior temporal regions (ATL) were most active when decisions were made with the benefit of a coherent context, suggesting a representational role. There was a graded shift in concreteness effects in this region, with dorsolateral areas particularly active for abstract words and ventromedial areas preferentially activated by concrete words. This supports the idea that concrete concepts are closely associated with visual experience and abstract concepts with auditory-verbal information; and that sub-regions of the ATL display graded specialisation for these two types of knowledge. Between these two extremes, we identified significant activations for both word types in ventrolateral ATL. This area is known to be involved in representing knowledge for concrete concepts; here we established that it is also activated by abstract concepts. These results converge with data from rTMS and neuropsychological investigations in

  8. 24 CFR 1000.48 - Are Indian preference requirements applicable to IHBG activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Are Indian preference requirements applicable to IHBG activities? 1000.48 Section 1000.48 Housing and Urban Development Regulations Relating to..., DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT NATIVE AMERICAN HOUSING ACTIVITIES General § 1000.48 Are Indian...

  9. 38 CFR 3.12a - Minimum active-duty service requirement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2013-07-01 2013-07-01 false Minimum active-duty service requirement. 3.12a Section 3.12a Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3.12a...

  10. 38 CFR 3.12a - Minimum active-duty service requirement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Minimum active-duty service requirement. 3.12a Section 3.12a Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3.12a...

  11. 38 CFR 3.12a - Minimum active-duty service requirement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2014-07-01 2014-07-01 false Minimum active-duty service requirement. 3.12a Section 3.12a Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3.12a...

  12. 38 CFR 3.12a - Minimum active-duty service requirement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2012-07-01 2012-07-01 false Minimum active-duty service requirement. 3.12a Section 3.12a Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3.12a...

  13. 38 CFR 3.12a - Minimum active-duty service requirement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2011-07-01 2011-07-01 false Minimum active-duty service requirement. 3.12a Section 3.12a Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS ADJUDICATION Pension, Compensation, and Dependency and Indemnity Compensation General § 3.12a...

  14. 40 CFR 35.3540 - Requirements for funding set-aside activities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... workplan describing how it will expend funds needed to provide technical assistance to public water systems... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Drinking Water State Revolving Funds § 35.3540 Requirements for funding set-aside activities. (a) General. If a State makes a grant or enters into a...

  15. 40 CFR 35.3540 - Requirements for funding set-aside activities.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... workplan describing how it will expend funds needed to provide technical assistance to public water systems... OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Drinking Water State Revolving Funds § 35.3540 Requirements for funding set-aside activities. (a) General. If a State makes a grant or enters into a...

  16. An interpolated activity during the knowledge-of-results delay interval eliminates the learning advantages of self-controlled feedback schedules.

    PubMed

    Carter, Michael J; Ste-Marie, Diane M

    2017-03-01

    The learning advantages of self-controlled knowledge-of-results (KR) schedules compared to yoked schedules have been linked to the optimization of the informational value of the KR received for the enhancement of one's error-detection capabilities. This suggests that information-processing activities that occur after motor execution, but prior to receiving KR (i.e., the KR-delay interval) may underlie self-controlled KR learning advantages. The present experiment investigated whether self-controlled KR learning benefits would be eliminated if an interpolated activity was performed during the KR-delay interval. Participants practiced a waveform matching task that required two rapid elbow extension-flexion reversals in one of four groups using a factorial combination of choice (self-controlled, yoked) and KR-delay interval (empty, interpolated). The waveform had specific spatial and temporal constraints, and an overall movement time goal. The results indicated that the self-controlled + empty group had superior retention and transfer scores compared to all other groups. Moreover, the self-controlled + interpolated and yoked + interpolated groups did not differ significantly in retention and transfer; thus, the interpolated activity eliminated the typically found learning benefits of self-controlled KR. No significant differences were found between the two yoked groups. We suggest the interpolated activity interfered with information-processing activities specific to self-controlled KR conditions that occur during the KR-delay interval and that these activities are vital for reaping the associated learning benefits. These findings add to the growing evidence that challenge the motivational account of self-controlled KR learning advantages and instead highlights informational factors associated with the KR-delay interval as an important variable for motor learning under self-controlled KR schedules.

  17. Personalized Knowledge Transfer for Caregiving Relatives.

    PubMed

    Wolff, Dominik; Behrends, Marianne; Gerlach, Mario; Kupka, Thomas; Marschollek, Michael

    2018-01-01

    Caregiving relatives have to manage very diverse tasks and need a lot of care-relevant knowledge. For most of them it is not easy to find the knowledge required. Thus, a personalized knowledge transfer for caregiving relatives is necessary. Against this background, methods to determine the personal relevance and importance of knowledge resources for caregiving relatives are developed. To evaluate these methods, an exemplary fictitious person is created by experts in Nursing Science. In this evaluation, the approach's results are compared with an expert opinion. The approach indicates that a personalized knowledge transfer is possible, providing caregiving relatives with necessary care knowledge according to their personal life situation.

  18. From science to action: Principles for undertaking environmental research that enables knowledge exchange and evidence-based decision-making.

    PubMed

    Cvitanovic, C; McDonald, J; Hobday, A J

    2016-12-01

    Effective conservation requires knowledge exchange among scientists and decision-makers to enable learning and support evidence-based decision-making. Efforts to improve knowledge exchange have been hindered by a paucity of empirically-grounded guidance to help scientists and practitioners design and implement research programs that actively facilitate knowledge exchange. To address this, we evaluated the Ningaloo Research Program (NRP), which was designed to generate new scientific knowledge to support evidence-based decisions about the management of the Ningaloo Marine Park in north-western Australia. Specifically, we evaluated (1) outcomes of the NRP, including the extent to which new knowledge informed management decisions; (2) the barriers that prevented knowledge exchange among scientists and managers; (3) the key requirements for improving knowledge exchange processes in the future; and (4) the core capacities that are required to support knowledge exchange processes. While the NRP generated expansive and multidisciplinary science outputs directly relevant to the management of the Ningaloo Marine Park, decision-makers are largely unaware of this knowledge and little has been integrated into decision-making processes. A range of barriers prevented efficient and effective knowledge exchange among scientists and decision-makers including cultural differences among the groups, institutional barriers within decision-making agencies, scientific outputs that were not translated for decision-makers and poor alignment between research design and actual knowledge needs. We identify a set of principles to be implemented routinely as part of any applied research program, including; (i) stakeholder mapping prior to the commencement of research programs to identify all stakeholders, (ii) research questions to be co-developed with stakeholders, (iii) implementation of participatory research approaches, (iv) use of a knowledge broker, and (v) tailored knowledge management

  19. Extra-team connections for knowledge transfer between staff teams

    PubMed Central

    Ramanadhan, Shoba; Wiecha, Jean L.; Emmons, Karen M.; Gortmaker, Steven L.; Viswanath, Kasisomayajula

    2009-01-01

    As organizations implement novel health promotion programs across multiple sites, they face great challenges related to knowledge management. Staff social networks may be a useful medium for transferring program-related knowledge in multi-site implementation efforts. To study this potential, we focused on the role of extra-team connections (ties between staff members based in different site teams) as potential channels for knowledge sharing. Data come from a cross-sectional study of afterschool childcare staff implementing a health promotion program at 20 urban sites of the Young Men's Christian Association of Greater Boston. We conducted a sociometric social network analysis and attempted a census of 91 program staff members. We surveyed 80 individuals, and included 73 coordinators and general staff, who lead and support implementation, respectively, in this study. A multiple linear regression model demonstrated a positive relationship between extra-team connections (β = 3.41, P < 0.0001) and skill receipt, a measure of knowledge transfer. We also found that intra-team connections (within-team ties between staff members) were also positively related to skill receipt. Connections between teams appear to support knowledge transfer in this network, but likely require greater active facilitation, perhaps via organizational changes. Further research on extra-team connections and knowledge transfer in low-resource, high turnover environments is needed. PMID:19528313

  20. The Effects of Physical Education Requirements on Physical Activity of Young Adults

    ERIC Educational Resources Information Center

    Mears, Derrick

    2008-01-01

    The purpose of this study was to determine if requiring multiple credits of high school physical education for graduation has an impact on promoting physical activity in young adults. Participants in this study (N=361) were surveyed concerning their high school physical education experiences and current performance of physical activity. Results…

  1. Constructing cardiovascular fitness knowledge in physical education

    PubMed Central

    Zhang, Tan; Chen, Ang; Chen, Senlin; Hong, Deockki; Loflin, Jerry; Ennis, Catherine

    2015-01-01

    In physical education, it has become necessary for children to learn kinesiological knowledge for understanding the benefits of physical activity and developing a physically active lifestyle. This study was conducted to determine the extent to which cognitive assignments about healthful living and fitness contributed to knowledge growth on cardiorespiratory fitness and health. Fourth grade students (N = 616) from 15 randomly sampled urban elementary schools completed 34 cognitive assignments related to the cardiorespiratory physical activities they were engaged in across 10 lessons. Performance on the assignments were analyzed in relation to their knowledge gain measured using a standardized knowledge test. A multivariate discriminant analysis revealed that the cognitive assignments contributed to knowledge gain but the contribution varied assignment by assignment. A multiple regression analysis indicated that students’ assignment performance by lesson contributed positively to their knowledge growth scores. A content analysis based on the constructivist learning framework showed that observing–reasoning assignments contributed the most to knowledge growth. Analytical and analytical–application assignments contributed less than the constructivist theories would predict. PMID:25995702

  2. Diabetes knowledge in nursing homes and home-based care services: a validation study of the Michigan Diabetes Knowledge Test adapted for use among nursing personnel.

    PubMed

    Haugstvedt, Anne; Aarflot, Morten; Igland, Jannicke; Landbakk, Tilla; Graue, Marit

    2016-01-01

    Providing high-quality diabetes care in nursing homes and home-based care facilities requires suitable instruments to evaluate the level of diabetes knowledge among the health-care providers. Thus, the aim of this study was to examine the psychometric properties of the Michigan Diabetes Knowledge Test adapted for use among nursing personnel. The study included 127 nursing personnel (32 registered nurses, 69 nursing aides and 26 nursing assistants) at three nursing homes and one home-based care facility in Norway. We examined the reliability and content and construct validity of the Michigan Diabetes Knowledge Test. The items in both the general diabetes subscale and the insulin-use subscale were considered relevant and appropriate. The instrument showed satisfactory properties for distinguishing between groups. Item response theory-based measurements and item information curves indicate maximum information at average or lower knowledge scores. Internal consistency and the item-total correlations were quite weak, indicating that the Michigan Diabetes Knowledge Test measures a set of items related to various relevant knowledge topics but not necessarily related to each other. The Michigan Diabetes Knowledge Test measures a broad range of topics relevant to diabetes care. It is an appropriate instrument for identifying individual and distinct needs for diabetes education among nursing personnel. The knowledge gaps identified by the Michigan Diabetes Knowledge Test could also provide useful input for the content of educational activities. However, some revision of the test should be considered.

  3. 77 FR 33479 - Information Collection Activities: Oil-Spill Response Requirements for Facilities Located Seaward...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ...-0010; OMB Control Number 1014-0007] Information Collection Activities: Oil-Spill Response Requirements... regulations under Part 254, ``Oil-Spill Response Requirements for Facilities Located Seaward of the Coast Line... 254, Oil-Spill Response Requirements for Facilities Located Seaward of the Coast Line. OMB Control...

  4. The educational value of Disaster Victim Identification (DVI) missions-transfer of knowledge.

    PubMed

    Winskog, Calle; Tonkin, Anne; Byard, Roger W

    2012-06-01

    Transfer of knowledge is the cornerstone of any educational organisation, with senior staff expected to participate in the training of less experienced colleagues and students. Teaching in the field is, however, slightly different, and a less theoretical approach is usually recommended. In terms of Disaster Victim Identification (DVI) activities, practical work under supervision of a field team stimulates tactile memory. A more practical approach is also useful when multiple organizations from a variety of countries are involved, as language barriers make it easier to manually show someone how to solve a problem, instead of attempting to explain complex concepts verbally. "See one, do one, teach one" is an approach that can be used to ensure that teaching is undertaken with the teacher grasping the essentials of a situation before passing on the information to someone else. The key principles of adult learning that need to be applied to DVI situations include the following: participants need to know why they are learning and to be motivated to learn by the need to solve problems; previous experience must be respected and built upon and learning approaches should match participants' background and diversity; and finally participants need to be actively involved in the learning process. Active learning involves the active acquisition of knowledge and/or skills during the performance of a task and characterizes DVI activities. Learning about DVI structure, activities and responsibilities incorporates both the learning of facts ("declarative knowledge") and practical skills ("procedural knowledge"). A fundamental requirement of all DVI exercises should be succession planning with involvement of less experienced colleagues at every opportunity so that essential teaching and learning opportunities are maximized. DVI missions provide excellent teaching opportunities and international agencies have a responsibility to teach less experienced colleagues and local staff

  5. Nuclear calcium is required for human T cell activation

    PubMed Central

    Samstag, Yvonne

    2016-01-01

    Calcium signals in stimulated T cells are generally considered single entities that merely trigger immune responses, whereas costimulatory events specify the type of reaction. Here we show that the “T cell calcium signal” is a composite signal harboring two distinct components that antagonistically control genomic programs underlying the immune response. Using human T cells from healthy individuals, we establish nuclear calcium as a key signal in human T cell adaptogenomics that drives T cell activation and is required for signaling to cyclic adenosine monophosphate response element–binding protein and the induction of CD25, CD69, interleukin-2, and γ-interferon. In the absence of nuclear calcium signaling, cytosolic calcium activating nuclear factor of activated T cells translocation directed the genomic response toward enhanced expression of genes that negatively modulate T cell activation and are associated with a hyporesponsive state. Thus, nuclear calcium controls the T cell fate decision between a proliferative immune response and tolerance. Modulators of nuclear calcium–driven transcription may be used to develop a new type of pro-tolerance immunosuppressive therapy. PMID:27810914

  6. Active prospective control is required for effective sensorimotor learning.

    PubMed

    Snapp-Childs, Winona; Casserly, Elizabeth; Mon-Williams, Mark; Bingham, Geoffrey P

    2013-01-01

    Passive modeling of movements is often used in movement therapy to overcome disabilities caused by stroke or other disorders (e.g. Developmental Coordination Disorder or Cerebral Palsy). Either a therapist or, recently, a specially designed robot moves or guides the limb passively through the movement to be trained. In contrast, action theory has long suggested that effective skill acquisition requires movements to be actively generated. Is this true? In view of the former, we explicitly tested the latter. Previously, a method was developed that allows children with Developmental Coordination Disorder to produce effective movements actively, so as to improve manual performance to match that of typically developing children. In the current study, we tested practice using such active movements as compared to practice using passive movement. The passive movement employed, namely haptic tracking, provided a strong test of the comparison, one that showed that the mere inaction of the muscles is not the problem. Instead, lack of prospective control was. The result was no effective learning with passive movement while active practice with prospective control yielded significant improvements in performance.

  7. A Knowledge-Based Arrangement of Prototypical Neural Representation Prior to Experience Contributes to Selectivity in Upcoming Knowledge Acquisition

    PubMed Central

    Kurashige, Hiroki; Yamashita, Yuichi; Hanakawa, Takashi; Honda, Manabu

    2018-01-01

    Knowledge acquisition is a process in which one actively selects a piece of information from the environment and assimilates it with prior knowledge. However, little is known about the neural mechanism underlying selectivity in knowledge acquisition. Here we executed a 2-day human experiment to investigate the involvement of characteristic spontaneous activity resembling a so-called “preplay” in selectivity in sentence comprehension, an instance of knowledge acquisition. On day 1, we presented 10 sentences (prior sentences) that were difficult to understand on their own. On the following day, we first measured the resting-state functional magnetic resonance imaging (fMRI). Then, we administered a sentence comprehension task using 20 new sentences (posterior sentences). The posterior sentences were also difficult to understand on their own, but some could be associated with prior sentences to facilitate their understanding. Next, we measured the posterior sentence-induced fMRI to identify the neural representation. From the resting-state fMRI, we extracted the appearances of activity patterns similar to the neural representations for posterior sentences. Importantly, the resting-state fMRI was measured before giving the posterior sentences, and thus such appearances could be considered as preplay-like or prototypical neural representations. We compared the intensities of such appearances with the understanding of posterior sentences. This gave a positive correlation between these two variables, but only if posterior sentences were associated with prior sentences. Additional analysis showed the contribution of the entorhinal cortex, rather than the hippocampus, to the correlation. The present study suggests that prior knowledge-based arrangement of neural activity before an experience contributes to the active selection of information to be learned. Such arrangement prior to an experience resembles preplay activity observed in the rodent brain. In terms of

  8. Tyrosine Kinase Btk Is Required for NK Cell Activation

    PubMed Central

    Bao, Yan; Zheng, Jian; Han, Chaofeng; Jin, Jing; Han, Huanxing; Liu, Yinping; Lau, Yu-Lung; Tu, Wenwei; Cao, Xuetao

    2012-01-01

    Bruton tyrosine kinase (Btk) is not only critical for B cell development and differentiation but is also involved in the regulation of Toll-like receptor-triggered innate response of macrophages. However, whether Btk is involved in the regulation of natural killer (NK) cell innate function remains unknown. Here, we show that Btk expression is up-regulated during maturation and activation of mouse NK cells. Murine Btk−/− NK cells have decreased innate immune responses to the TLR3 ligand, with reduced expressions of IFN-γ, perforin, and granzyme-B and decreased cytotoxic activity. Furthermore, Btk is found to promote TLR3-triggered NK cell activation mainly by activating the NF-κB pathway. Poly(I:C)-induced NK cell-mediated acute hepatitis was observed to be attenuated in Btk−/− mice or the mice with in vivo administration of the Btk inhibitor. Correspondingly, liver damage was aggravated in Btk−/− mice after the adoptive transfer of Btk+/+ NK cells, further indicating that Btk-mediated NK cell activation contributes to TLR3-triggered acute liver injury. Importantly, reduced TLR3-triggered activation of human NK cells was observed in Btk-deficient patients with X-linked agammaglobulinemia, as evidenced by the reduced IFN-γ, CD69, and CD107a expression and cytotoxic activity. These results indicate that Btk is required for activation of NK cells, thus providing insight into the physiological significance of Btk in the regulation of immune cell functions and innate inflammatory response. PMID:22589540

  9. Tyrosine kinase Btk is required for NK cell activation.

    PubMed

    Bao, Yan; Zheng, Jian; Han, Chaofeng; Jin, Jing; Han, Huanxing; Liu, Yinping; Lau, Yu-Lung; Tu, Wenwei; Cao, Xuetao

    2012-07-06

    Bruton tyrosine kinase (Btk) is not only critical for B cell development and differentiation but is also involved in the regulation of Toll-like receptor-triggered innate response of macrophages. However, whether Btk is involved in the regulation of natural killer (NK) cell innate function remains unknown. Here, we show that Btk expression is up-regulated during maturation and activation of mouse NK cells. Murine Btk(-/-) NK cells have decreased innate immune responses to the TLR3 ligand, with reduced expressions of IFN-γ, perforin, and granzyme-B and decreased cytotoxic activity. Furthermore, Btk is found to promote TLR3-triggered NK cell activation mainly by activating the NF-κB pathway. Poly(I:C)-induced NK cell-mediated acute hepatitis was observed to be attenuated in Btk(-/-) mice or the mice with in vivo administration of the Btk inhibitor. Correspondingly, liver damage was aggravated in Btk(-/-) mice after the adoptive transfer of Btk(+/+) NK cells, further indicating that Btk-mediated NK cell activation contributes to TLR3-triggered acute liver injury. Importantly, reduced TLR3-triggered activation of human NK cells was observed in Btk-deficient patients with X-linked agammaglobulinemia, as evidenced by the reduced IFN-γ, CD69, and CD107a expression and cytotoxic activity. These results indicate that Btk is required for activation of NK cells, thus providing insight into the physiological significance of Btk in the regulation of immune cell functions and innate inflammatory response.

  10. New strategies to strengthen the soil science knowledge of student during field activities

    NASA Astrophysics Data System (ADS)

    Benito, Marta; Hontoria, Chiquinquirá; Masaguer, Alberto; Diéguez, Carmen; Almorox, Javier; Pérez, Juana; Santano, Jesús; Mariscal, Ignacio; Gutiérrez, Jesús; Moliner, Ana

    2013-04-01

    Soil Science can be considered a discipline that serves as a fundamental base for other disciplines such as ecology, agronomy, plant production, etc. In order to demonstrate the relevance and connection to real world it is important to develop field and practical activities. Field activities help student to comprehend soil as part of the landscape and the natural ecosystems. These activities also help them to realize the importance of historical soil use on the quality of todaýs soil and landscapes. It is well known that fieldwork practices are essential to strengthen the soil science knowledge of students and their learning process. These fieldwork practices involve doing a physical activity rather than passively attending lectures or watching demonstrations. The simple visual and tactile observations in the field could be used to predict soil behavior and these direct observations are best made in the field. Students who learned in the field using an active work are more motivated, have more positive attitudes, and place more value in their work than those that learn passively. Therefore, when scheduling the coursework an important time is assigned to field work, which sometimes is not sufficiently profited from the standpoint of student learning taking into consideration the economic effort involved. We are aware that part of the students are simple spectators in the field so we encourage their participation by making them responsible for obtaining part of the information about the place and the types of soils that will be visited. On the other hand, we will invite the students to do some game based exercises, which are fun and force them to work in groups and to pay attention to explanations. Our objective is to present the information in a more attractive way, making the learning of soil profile description and easier task. The exercises that we propose are both field and problem-based learning to make sure that the knowledge is more memorable (non

  11. Effect of Knowledge Integration Activities on Students' Perception of the Earth's Crust as a Cyclic System.

    ERIC Educational Resources Information Center

    Kali, Yael; Orion, Nir; Eylon, Bat-Sheva

    2003-01-01

    Characterizes students' understanding of the rock cycle system. Examines effects of a knowledge integration activity on their system thinking. Interprets answers to an open-ended test using a systems thinking continuum ranging from a completely static view of the system to an understanding of the system's cyclic nature. Reports meaningful…

  12. Antileishmanial activities of dihydrochalcones from piper elongatum and synthetic related compounds. Structural requirements for activity.

    PubMed

    Hermoso, Alicia; Jiménez, Ignacio A; Mamani, Zulma A; Bazzocchi, Isabel L; Piñero, José E; Ravelo, Angel G; Valladares, Basilio

    2003-09-01

    Two dihydrochalcones (1 and 2) were isolated from Piper elongatum Vahl by activity-guided fractionation against extracellular promastigotes of Leishmania braziliensis in vitro. Their structures were elucidated by spectral analysis, including homonuclear and heteronuclear correlation NMR experiments. Derivatives 3-7 and 20 synthetic related compounds (8-27) were also assayed to establish the structural requirements for antileishmanial activity. Compounds 1-11 that proved to be more active that ketoconazol, used as positive control, were further assayed against promastigotes of Leishmania tropica and Leishmania infantum. Compounds 7 and 11, with a C(6)-C(3)-C(6) system, proved to be the most promising compounds, with IC(50) values of 2.98 and 3.65 microg/mL, respectively, and exhibited no toxic effect on macrophages (around 90% viability). Correlation between the molecular structures and antileishmanial activity is discussed in detail.

  13. [Connection between the knowledge of the recommendations of the National Nutrition and Health Program and patterns of eating behaviour and physical activity].

    PubMed

    Escalon, H; Beck, F; Bossard, C

    2013-02-01

    Nutrition education is one of the main lines of the French nutrition policy that has been undertaken for several years. The underlying hypothesis of this approach is that knowledge improvement is one of the ways likely to contribute to health-enhancing diet and physical activity. The objective of this paper, based on the 2008 Health and nutrition Barometer, is to examine the associations observed between knowledge and behavior with regard to diet and physical activity. The 2008 Health and nutrition Barometer is a nationally representative telephone survey conducted on 4714 individuals aged 12-75 years. For six recommendations of the National Nutrition and Health Program (Programme national nutrition santé [PNNS]), multiple logistic models were used to identify associations between knowledge of these recommendations and behavior, among adults aged 18-75 years. For food consumed on the day before the interview, odds ratios were adjusted for sex, age, education level, agglomeration size and region. As bivariate analysis showed that income level was significant for recommended consumption of fish, this variable was introduced among adjustment variables. Similarly, the variable occupation was introduced for physical activity. A positive association between knowledge of recommendations and nutritional behavior on the day before interview was observed for fruit and vegetables (OR=1.7), dairy products (OR=1.6), and starchy food (OR=1.6). The same was observed for consumption of fish during the 15 days before the interview (OR=5.0) and for physical activity during a usual week (OR=1.5) but not for the "meat, seafood and eggs" food group. Eating habits and physical activity are positively associated with knowledge of nutritional recommendations, mainly acquired via nutritional information and educational actions. Nevertheless, the important differences observed for certain dietary groups between knowledge of recommendations and dietary intake emphasizes the need to further

  14. U.S. Spacesuit Knowledge Capture Series Catalog

    NASA Technical Reports Server (NTRS)

    Bitterly, Rose; Oliva, Vladenka

    2012-01-01

    The National Aeronautics and Space Administration (NASA) and other organizations have been performing U.S. Spacesuit Knowledge Capture (USSKC) since the beginning of space exploration through published reports, conference presentations, specialized seminars, and classes instructed by veterans in the field. The close physical interaction between spacesuit systems and human beings makes them among the most personally evocative pieces of space hardware. Consequently, spacesuit systems have required nearly constant engineering refinements to do their jobs without impinging on human activity. Since 2008, spacesuit knowledge capture has occurred through video recording, engaging both current and former specialists presenting technical scope specifically to educate individuals and preserve knowledge. These archives of spacesuit legacy reflect its rich history and will provide knowledge that will enhance the chances for the success of future and more ambitious spacesuit system programs. The scope and topics of USSKC have included lessons learned in spacesuit technology; experience from the Gemini, Apollo, Skylab, and Shuttle Programs; the process of hardware certification, design, development, and other program components; spacesuit evolution and experience; failure analysis and resolution; and aspects of program management. USSKC activities have progressed to a level where NASA, the National Air and Space Museum (NASM), Hamilton Sundstrand (HS) and the spacesuit community are now working together to provide a comprehensive way to organize and archive intra-agency information related to the development of spacesuit systems. These video recordings are currently being reviewed for public release using NASA export control processes. After a decision is made for either public or non-public release (internal NASA only), the videos and presentations will be available through the NASA Johnson Space Center Engineering Directorate (EA) Engineering Academy, the NASA Technical

  15. 77 FR 6815 - Agency Information Collection Activities: Country of Origin Marking Requirements for Containers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    ... Activities: Country of Origin Marking Requirements for Containers or Holders AGENCY: U.S. Customs and Border... information collection requirement concerning Country of Origin Marking Requirements for Containers or Holders... request for Office of Management and Budget (OMB) approval. All comments will become a matter of public...

  16. 20 CFR 404.1321 - Ninety-day active service requirement for post-World War II veterans.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... post-World War II veterans. 404.1321 Section 404.1321 Employees' Benefits SOCIAL SECURITY... of the Uniformed Services Post-World War II Veterans § 404.1321 Ninety-day active service requirement for post-World War II veterans. (a) The 90 days of active service required for post-World War II...

  17. 20 CFR 404.1321 - Ninety-day active service requirement for post-World War II veterans.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... post-World War II veterans. 404.1321 Section 404.1321 Employees' Benefits SOCIAL SECURITY... of the Uniformed Services Post-World War II Veterans § 404.1321 Ninety-day active service requirement for post-World War II veterans. (a) The 90 days of active service required for post-World War II...

  18. 20 CFR 404.1321 - Ninety-day active service requirement for post-World War II veterans.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... post-World War II veterans. 404.1321 Section 404.1321 Employees' Benefits SOCIAL SECURITY... of the Uniformed Services Post-World War II Veterans § 404.1321 Ninety-day active service requirement for post-World War II veterans. (a) The 90 days of active service required for post-World War II...

  19. 20 CFR 404.1321 - Ninety-day active service requirement for post-World War II veterans.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... post-World War II veterans. 404.1321 Section 404.1321 Employees' Benefits SOCIAL SECURITY... of the Uniformed Services Post-World War II Veterans § 404.1321 Ninety-day active service requirement for post-World War II veterans. (a) The 90 days of active service required for post-World War II...

  20. Active Knowledge Structures for Natural Language Processing.

    DTIC Science & Technology

    1991-01-01

    specialist belief: Assume there is a lambda-expression "(LAMBDA L) immed-type-ofL" and Z = ((LAMBDA L) immed-type-of L) ( thalassemia ), we can describe...SPEC) -> ([AVG-PERSON] -> (VAL-FOR) -> CGREEK-PLCE)3 This expresses the various levels of specialized knowledge of thalassemia , depending on

  1. Knowledge and institutional requirements to promote land degradation neutrality in drylands - An analysis of the outcomes of the 3rd UNCCD scientific conference

    NASA Astrophysics Data System (ADS)

    Akhtar-Schuster, Mariam; Safriel, Uriel; Abraham, Elena; de Vente, Joris; Essahli, Wafa; Escadafal, Richard; Stringer, Lindsay

    2015-04-01

    Achieving land degradation neutrality (LDN) through sustainable land management (SLM) targets the maintenance or restoration of the productivity of land, and therefore has to include decision-makers, knowledge generators and knowledge holders at the different relevant geographic scales. In order to enhance the implementation of the Convention, the Conference of the Parties (COP) of the United Nations Convention to Combat Desertification therefore decided that each future session of its Committee on Science and Technology (CST) would be organized in a predominantly scientific and technical conference-style format. This contribution will outline the major outcomes of UNCCD's 3rd scientific conference that will be held in Cancún, Mexico, from 9 to 12 March 2015, on addressing desertification, land degradation and drought issues (DLDD) for poverty reduction and sustainable development. The conference follows an exceptional new round table conference format that will allow the various stakeholders to discuss scientific as well as the contribution of traditional knowledge and practices in combating land degradation. This format should provide two-way communication and enable deeper insight into the availability and contribution of all forms of knowledge for achieving LDN through the assessment of: • the vulnerability of lands to DLDD and climate change and the adaptive capacities of socio-ecosystems; • best examples of adapted, knowledge-based practices and technologies; • monitoring and assessment methods to evaluate the effectiveness of adaptation practices and technologies. The outcomes of UNCCD's 3rd scientific conference will serve as a basis for discussing: • contributions of science to diagnose the status of land; • research gaps that need to be addressed to achieve LDN for poverty reduction; • additional institutional requirements to optimally bridge knowledge generation, knowledge maintenance and knowledge implementation at the science

  2. Sparse representation of electrodermal activity with knowledge-driven dictionaries.

    PubMed

    Chaspari, Theodora; Tsiartas, Andreas; Stein, Leah I; Cermak, Sharon A; Narayanan, Shrikanth S

    2015-03-01

    Biometric sensors and portable devices are being increasingly embedded into our everyday life, creating the need for robust physiological models that efficiently represent, analyze, and interpret the acquired signals. We propose a knowledge-driven method to represent electrodermal activity (EDA), a psychophysiological signal linked to stress, affect, and cognitive processing. We build EDA-specific dictionaries that accurately model both the slow varying tonic part and the signal fluctuations, called skin conductance responses (SCR), and use greedy sparse representation techniques to decompose the signal into a small number of atoms from the dictionary. Quantitative evaluation of our method considers signal reconstruction, compression rate, and information retrieval measures, that capture the ability of the model to incorporate the main signal characteristics, such as SCR occurrences. Compared to previous studies fitting a predetermined structure to the signal, results indicate that our approach provides benefits across all aforementioned criteria. This paper demonstrates the ability of appropriate dictionaries along with sparse decomposition methods to reliably represent EDA signals and provides a foundation for automatic measurement of SCR characteristics and the extraction of meaningful EDA features.

  3. The Effect of Outdoor Learning Activities on the Development of Preschool Children

    ERIC Educational Resources Information Center

    Yildirim, Günseli; Özyilmaz Akamca, Güzin

    2017-01-01

    Learning ought to be supported by both in class activities and outdoor activities contributing to structuring knowledge. Outdoor activities allow children to actively participate and to learn by doing. Learning requires a lot of work and activities. These activities, which provide primary experiences, help children to change theoretical knowledge…

  4. The Role of Specificity, Targeted Learning Activities, and Prior Knowledge for the Effects of Relevance Instructions

    ERIC Educational Resources Information Center

    Roelle, Julian; Lehmkuhl, Nina; Beyer, Martin-Uwe; Berthold, Kirsten

    2015-01-01

    In 2 experiments we examined the role of (a) specificity, (b) the type of targeted learning activities, and (c) learners' prior knowledge for the effects of relevance instructions on learning from instructional explanations. In Experiment 1, we recruited novices regarding the topic of atomic structure (N = 80) and found that "specific"…

  5. Development of a Knowledge Base for Enduser Consultation of AAL-Systems.

    PubMed

    Röll, Natalie; Stork, Wilhelm; Rosales, Bruno; Stephan, René; Knaup, Petra

    2016-01-01

    Manufacturer information, user experiences and product availability of assistive living technologies are usually not known to citizens or consultation centers. The different knowledge levels concerning the availability of technology shows the need for building up a knowledge base. The aim of this contribution is the definition of requirements in the development of knowledge bases for AAL consultations. The major requirements, such as a maintainable and easy to use structure were implemented into a web based knowledge base, which went productive in ~3700 consulting interviews of municipal technology information centers. Within this field phase the implementation of the requirements for a knowledge base in the field of AAL consulting was evaluated and further developed.

  6. Calcium mobilization and Rac1 activation are required for VCAM-1 (vascular cell adhesion molecule-1) stimulation of NADPH oxidase activity.

    PubMed Central

    Cook-Mills, Joan M; Johnson, Jacob D; Deem, Tracy L; Ochi, Atsuo; Wang, Lei; Zheng, Yi

    2004-01-01

    VCAM-1 (vascular cell adhesion molecule-1) plays an important role in the regulation of inflammation in atherosclerosis, asthma, inflammatory bowel disease and transplantation. VCAM-1 activates endothelial cell NADPH oxidase, and this oxidase activity is required for VCAM-1-dependent lymphocyte migration. We reported previously that a mouse microvascular endothelial cell line promotes lymphocyte migration that is dependent on VCAM-1, but not on other known adhesion molecules. Here we have investigated the signalling mechanisms underlying VCAM-1 function. Lymphocyte binding to VCAM-1 on the endothelial cell surface activated an endothelial cell calcium flux that could be inhibited with anti-alpha4-integrin and mimicked by anti-VCAM-1-coated beads. VCAM-1 stimulation of calcium responses could be blocked by an inhibitor of intracellular calcium mobilization, a calcium channel inhibitor or a calcium chelator, resulting in the inhibition of NADPH oxidase activity. Addition of ionomycin overcame the calcium channel blocker suppression of VCAM-1-stimulated NADPH oxidase activity, but could not reverse the inhibitory effect imposed by intracellular calcium blockage, indicating that both intracellular and extracellular calcium mobilization are required for VCAM-1-mediated activation of NADPH oxidase. Furthermore, VCAM-1 specifically activated the Rho-family GTPase Rac1, and VCAM-1 activation of NADPH oxidase was blocked by a dominant negative Rac1. Thus VCAM-1 stimulates the mobilization of intracellular and extracellular calcium and Rac1 activity that are required for the activation of NADPH oxidase. PMID:14594451

  7. Investigating TPACK: Knowledge Growth in Teaching with Technology

    ERIC Educational Resources Information Center

    Niess, Margaret L.

    2011-01-01

    Technological pedagogical and content knowledge (TPACK) presents a dynamic framework for describing teachers' knowledge required for designing, implementing, and evaluating curriculum and instruction with technology. TPACK strategic thinking includes knowing when, where, and how to use domain-specific knowledge and strategies for guiding students'…

  8. Perception, Knowledge, and Attitude toward Physical Activity Behaviour: Implications for Participation among Individuals with Essential Hypertension.

    PubMed

    Maruf, Fatai Adesina; Ojukwu, C C; Akindele, M O

    2018-03-01

    Understanding lifestyle behavior among individuals with hypertension is important for achieving hypertension control. This study explored perception, knowledge, attitude and participation in physical activity (PA) among individuals with hypertension attending tertiary hospitals in a south-eastern Nigerian state. This cross-sectional survey involved 200 individuals with hypertension from the Out-Patient Departments of the two teaching hospitals in Anambra State, Nigeria. Information on age, education level, gender, height, sleep duration, perception of PA, knowledge about PA, attitude towards PA, and participation in PA was collected using a self-developed and pilot-tested questionnaire. Blood pressure (BP), height, body weight, and waist circumference were measured using standardized procedures. PA level was assessed using 7-Day International PA Questionnaire. Majority of participants reported good perceptions of PA behavior, in terms of not being discouraged by relations and friends, and of its benefits. They reported good knowledge about PA behavior. The participants demonstrated positive attitude in terms of benefits, importance, and involved risk of PA, and reported high level of participation in PA. There were significant correlations among knowledge about PA, attitude towards PA and participation in PA. PA level generally correlated significantly with attitude and participation in PA CONCLUSIONS: Perceived high level of participation in PA in this study sample can be attributed to their much knowledge and positive attitude towards PA. Increasing the knowledge about PA among individuals with hypertension by creating awareness about benefits and utilization of PA will improve their attitudes towards PA, and thereby fosters their participation in PA.

  9. Parental Knowledge of Adolescents' Online Content and Contact Risks.

    PubMed

    Symons, Katrien; Ponnet, Koen; Emmery, Kathleen; Walrave, Michel; Heirman, Wannes

    2017-02-01

    Parental knowledge about adolescents' activities is an identified protective factor in terms of adolescent adjustment. While research on parental knowledge has focused on adolescents' offline behavior, there is little empirical understanding of parental knowledge about adolescents' online behavior. This study investigates parental knowledge about adolescents' online activities and experiences with online risks, as well as the correlates of such knowledge. Building on former research, open communication and knowledge-generating monitoring practices are investigated as potential correlates of parental knowledge. Use is made of triadic data, relying on reports from children aged 13 to 18, mothers and fathers within the same family (N = 357 families; 54.9 % female adolescents). The results showed that parents have little knowledge about the occurrence of online risks and their children's online activities. While mothers did not have more accurate knowledge compared to fathers, they did perceive themselves to be more knowledgeable than fathers. Associations between parental knowledge and hypothesized correlates were tested by means of one-way ANOVA tests and stepwise logistic regression models. Limited evidence was found for associations with parents' accurate knowledge about the occurrence of online risks. Engagement in knowledge-generating monitoring practices was linked to mothers and fathers' self-perceived knowledge about their children's online activities. For mothers, open communication with the child was linked to self-perceived knowledge. The findings suggest that parents need to be more aware of the possibility that online risks might occur and that more research needs to be done in order to understand what parents can do to improve their accurate knowledge.

  10. Activation of phenylalanine hydroxylase by phenylalanine does not require binding in the active site.

    PubMed

    Roberts, Kenneth M; Khan, Crystal A; Hinck, Cynthia S; Fitzpatrick, Paul F

    2014-12-16

    Phenylalanine hydroxylase (PheH), a liver enzyme that catalyzes the hydroxylation of excess phenylalanine in the diet to tyrosine, is activated by phenylalanine. The lack of activity at low levels of phenylalanine has been attributed to the N-terminus of the protein's regulatory domain acting as an inhibitory peptide by blocking substrate access to the active site. The location of the site at which phenylalanine binds to activate the enzyme is unknown, and both the active site in the catalytic domain and a separate site in the N-terminal regulatory domain have been proposed. Binding of catecholamines to the active-site iron was used to probe the accessibility of the active site. Removal of the regulatory domain increases the rate constants for association of several catecholamines with the wild-type enzyme by ∼2-fold. Binding of phenylalanine in the active site is effectively abolished by mutating the active-site residue Arg270 to lysine. The k(cat)/K(phe) value is down 10⁴ for the mutant enzyme, and the K(m) value for phenylalanine for the mutant enzyme is >0.5 M. Incubation of the R270K enzyme with phenylalanine also results in a 2-fold increase in the rate constants for catecholamine binding. The change in the tryptophan fluorescence emission spectrum seen in the wild-type enzyme upon activation by phenylalanine is also seen with the R270K mutant enzyme in the presence of phenylalanine. Both results establish that activation of PheH by phenylalanine does not require binding of the amino acid in the active site. This is consistent with a separate allosteric site, likely in the regulatory domain.

  11. Activation of Phenylalanine Hydroxylase by Phenylalanine Does Not Require Binding in the Active Site

    PubMed Central

    2015-01-01

    Phenylalanine hydroxylase (PheH), a liver enzyme that catalyzes the hydroxylation of excess phenylalanine in the diet to tyrosine, is activated by phenylalanine. The lack of activity at low levels of phenylalanine has been attributed to the N-terminus of the protein’s regulatory domain acting as an inhibitory peptide by blocking substrate access to the active site. The location of the site at which phenylalanine binds to activate the enzyme is unknown, and both the active site in the catalytic domain and a separate site in the N-terminal regulatory domain have been proposed. Binding of catecholamines to the active-site iron was used to probe the accessibility of the active site. Removal of the regulatory domain increases the rate constants for association of several catecholamines with the wild-type enzyme by ∼2-fold. Binding of phenylalanine in the active site is effectively abolished by mutating the active-site residue Arg270 to lysine. The kcat/Kphe value is down 104 for the mutant enzyme, and the Km value for phenylalanine for the mutant enzyme is >0.5 M. Incubation of the R270K enzyme with phenylalanine also results in a 2-fold increase in the rate constants for catecholamine binding. The change in the tryptophan fluorescence emission spectrum seen in the wild-type enzyme upon activation by phenylalanine is also seen with the R270K mutant enzyme in the presence of phenylalanine. Both results establish that activation of PheH by phenylalanine does not require binding of the amino acid in the active site. This is consistent with a separate allosteric site, likely in the regulatory domain. PMID:25453233

  12. An Intelligent Tool for Activity Data Collection

    PubMed Central

    Jehad Sarkar, A. M.

    2011-01-01

    Activity recognition systems using simple and ubiquitous sensors require a large variety of real-world sensor data for not only evaluating their performance but also training the systems for better functioning. However, a tremendous amount of effort is required to setup an environment for collecting such data. For example, expertise and resources are needed to design and install the sensors, controllers, network components, and middleware just to perform basic data collections. It is therefore desirable to have a data collection method that is inexpensive, flexible, user-friendly, and capable of providing large and diverse activity datasets. In this paper, we propose an intelligent activity data collection tool which has the ability to provide such datasets inexpensively without physically deploying the testbeds. It can be used as an inexpensive and alternative technique to collect human activity data. The tool provides a set of web interfaces to create a web-based activity data collection environment. It also provides a web-based experience sampling tool to take the user’s activity input. The tool generates an activity log using its activity knowledge and the user-given inputs. The activity knowledge is mined from the web. We have performed two experiments to validate the tool’s performance in producing reliable datasets. PMID:22163832

  13. An intelligent tool for activity data collection.

    PubMed

    Sarkar, A M Jehad

    2011-01-01

    Activity recognition systems using simple and ubiquitous sensors require a large variety of real-world sensor data for not only evaluating their performance but also training the systems for better functioning. However, a tremendous amount of effort is required to setup an environment for collecting such data. For example, expertise and resources are needed to design and install the sensors, controllers, network components, and middleware just to perform basic data collections. It is therefore desirable to have a data collection method that is inexpensive, flexible, user-friendly, and capable of providing large and diverse activity datasets. In this paper, we propose an intelligent activity data collection tool which has the ability to provide such datasets inexpensively without physically deploying the testbeds. It can be used as an inexpensive and alternative technique to collect human activity data. The tool provides a set of web interfaces to create a web-based activity data collection environment. It also provides a web-based experience sampling tool to take the user's activity input. The tool generates an activity log using its activity knowledge and the user-given inputs. The activity knowledge is mined from the web. We have performed two experiments to validate the tool's performance in producing reliable datasets.

  14. Substrate Shuttling Between Active Sites of Uroporphyrinogen Decarboxylase in Not Required to Generate Coproporphyrinogen

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Phillips, J.; Warby, C; Whitby, F

    2009-01-01

    Uroporphyrinogen decarboxylase (URO-D; EC 4.1.1.37), the fifth enzyme of the heme biosynthetic pathway, is required for the production of heme, vitamin B12, siroheme, and chlorophyll precursors. URO-D catalyzes the sequential decarboxylation of four acetate side chains in the pyrrole groups of uroporphyrinogen to produce coproporphyrinogen. URO-D is a stable homodimer, with the active-site clefts of the two subunits adjacent to each other. It has been hypothesized that the two catalytic centers interact functionally, perhaps by shuttling of reaction intermediates between subunits. We tested this hypothesis by construction of a single-chain protein (single-chain URO-D) in which the two subunits were connectedmore » by a flexible linker. The crystal structure of this protein was shown to be superimposable with wild-type activity and to have comparable catalytic activity. Mutations that impaired one or the other of the two active sites of single-chain URO-D resulted in approximately half of wild-type activity. The distributions of reaction intermediates were the same for mutant and wild-type sequences and were unaltered in a competition experiment using I and III isomer substrates. These observations indicate that communication between active sites is not required for enzyme function and suggest that the dimeric structure of URO-D is required to achieve conformational stability and to create a large active-site cleft.« less

  15. Encouraging post-stroke patients to be active seems possible: results of an intervention study with knowledge brokers.

    PubMed

    Willems, Mia; Schröder, Carin; van der Weijden, Trudy; Post, Marcel W; Visser-Meily, Anne M

    2016-08-01

    Although physical activity and exercise for stroke patients is highly recommended for fast recovery, patients in hospitals and rehabilitation centres are insufficiently encouraged to be physically active. In this study, we investigated the impact of knowledge brokers (KBs), enterprising nurses and therapists, on health professionals' (HP) performance to encourage stroke inpatients to be physically active. This multicenter intervention study used a pre-post test design. Two or three KBs were trained in each stroke unit of 12 hospitals and 10 rehabilitation centres in The Netherlands. Questionnaires were completed by patients and HPs before and after the KB-intervention. The primary outcome was encouragement given by HPs to their patients to be physically active, as reported by patients and HPs. After the KB-intervention, many more patients (48%; N=217) reported at least some encouragement by HPs to be physically active than before (26%; N=243, p<0.000). HPs (N=288) on an average reported encouraging patients more often after the intervention, but this difference was significant only for occupational therapists and KBs. Based on patient's reports of HP behaviour, the KB-intervention appears effective since more patients felt encouraged to be physically active after the intervention compared to before. Replication of this study in an experimental design is needed to allow causal inferences. Implications for rehabilitation We advise rehabilitation teams to make use of knowledge brokers (KBs), since the KB-intervention was shown to increase the encouragement felt by stroke patients to be physically active. It seems worthwhile to involve physicians, nurses and patients' families more frequently in efforts to encourage stroke patients to be physically active.

  16. Activated Rac1 requires gp130 for Stat3 activation, cell proliferation and migration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Arulanandam, Rozanne; Geletu, Mulu; Feracci, Helene

    2010-03-10

    Rac1 (Rac) is a member of the Rho family of small GTPases which controls cell migration by regulating the organization of actin filaments. Previous results suggested that mutationally activated forms of the Rho GTPases can activate the Signal Transducer and Activator of Transcription-3 (Stat3), but the exact mechanism is a matter of controversy. We recently demonstrated that Stat3 activity of cultured cells increases dramatically following E-cadherin engagement. To better understand this pathway, we now compared Stat3 activity levels in mouse HC11 cells before and after expression of the mutationally activated Rac1 (Rac{sup V12}), at different cell densities. The results revealedmore » for the first time a dramatic increase in protein levels and activity of both the endogenous Rac and Rac{sup V12} with cell density, which was due to inhibition of proteasomal degradation. In addition, Rac{sup V12}-expressing cells had higher Stat3, tyrosine-705 phosphorylation and activity levels at all densities, indicating that Rac{sup V12} is able to activate Stat3. Further examination of the mechanism of Stat3 activation showed that Rac{sup V12} expression caused a surge in mRNA of Interleukin-6 (IL6) family cytokines, known potent Stat3 activators. Knockdown of gp130, the common subunit of this family reduced Stat3 activity, indicating that these cytokines may be responsible for the Stat3 activation by Rac{sup V12}. The upregulation of IL6 family cytokines was required for cell migration and proliferation induced by Rac{sup V12}, as shown by gp130 knockdown experiments, thus demonstrating that the gp130/Stat3 axis represents an essential effector of activated Rac for the regulation of key cellular functions.« less

  17. Dietary selenium requirements based on tissue selenium concentration and glutathione peroxidase activities in old female rats.

    PubMed

    Sunde, Roger A; Thompson, Kevin M

    2009-01-01

    Dietary nutrient requirements for older animals have been studied far less than have requirements for young growing animals. To determine dietary selenium (Se) requirements in old rats, we fed female weanling rats a Se-deficient diet (0.007 microg Se/g) or supplemented rats with graded levels of dietary Se (0-0.3 microg Se/g) as Na(2)SeO(3) for 52 weeks. At no point did Se deficiency or level of Se supplementation have a significant effect (P>0.05) on growth. To determine Se requirements, Se response curves were determined for 7 Se-dependent parameters. We found that minimum dietary Se requirements in year-old female rats were at or below 0.05 microg Se/g diet based on liver Se, red blood cell glutathione peroxidase (Gpx1) activity, plasma Gpx3 activity, liver and kidney Gpx1 activity, and liver and kidney Gpx4 activity. In conclusion, this study found that dietary Se requirements in old female rats were decreased at least 50% relative to requirements found in young, rapidly growing female rats. Collectively, this indicates that the homeostatic mechanisms related to retention and maintenance of Se status are still fully functional in old female rats.

  18. TARGET's role in knowledge acquisition, engineering, validation, and documentation

    NASA Technical Reports Server (NTRS)

    Levi, Keith R.

    1994-01-01

    We investigate the use of the TARGET task analysis tool for use in the development of rule-based expert systems. We found TARGET to be very helpful in the knowledge acquisition process. It enabled us to perform knowledge acquisition with one knowledge engineer rather than two. In addition, it improved communication between the domain expert and knowledge engineer. We also found it to be useful for both the rule development and refinement phases of the knowledge engineering process. Using the network in these phases required us to develop guidelines that enabled us to easily translate the network into production rules. A significant requirement for TARGET remaining useful throughout the knowledge engineering process was the need to carefully maintain consistency between the network and the rule representations. Maintaining consistency not only benefited the knowledge engineering process, but also has significant payoffs in the areas of validation of the expert system and documentation of the knowledge in the system.

  19. Supporting Students' Knowledge Transfer in Modeling Activities

    ERIC Educational Resources Information Center

    Piksööt, Jaanika; Sarapuu, Tago

    2014-01-01

    This study investigates ways to enhance secondary school students' knowledge transfer in complex science domains by implementing question prompts. Two samples of students applied two web-based models to study molecular genetics--the model of genetic code (n = 258) and translation (n = 245). For each model, the samples were randomly divided into…

  20. There and Back Again: From Research Methods to Principles of Learning, and Everything in Between: Consolidated Knowledge Using the Course Wiki

    ERIC Educational Resources Information Center

    Hogendoorn, Adrian

    2017-01-01

    A course wiki is an active environment in which students not only solve problems, but also find their own problems (Bransford, Brown, & Cocking, 1999). Wikis are novel, immersive environments requiring active participation, which enable students to build knowledge within a secure online setting (Hadjerrouit, 2011). This contribution traces a…

  1. When knowledge activated from memory intrudes on probabilistic inferences from description - the case of stereotypes.

    PubMed

    Dorrough, Angela R; Glöckner, Andreas; Betsch, Tilmann; Wille, Anika

    2017-10-01

    To make decisions in probabilistic inference tasks, individuals integrate relevant information partly in an automatic manner. Thereby, potentially irrelevant stimuli that are additionally presented can intrude on the decision process (e.g., Söllner, Bröder, Glöckner, & Betsch, 2014). We investigate whether such an intrusion effect can also be caused by potentially irrelevant or even misleading knowledge activated from memory. In four studies that combine a standard information board paradigm from decision research with a standard manipulation from social psychology, we investigate the case of stereotypes and demonstrate that stereotype knowledge can yield intrusion biases in probabilistic inferences from description. The magnitude of these biases increases with stereotype accessibility and decreases with a clarification of the rational solution. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Eating habits and behaviors, physical activity, nutritional and food safety knowledge and beliefs in an adolescent Italian population.

    PubMed

    Turconi, Giovanna; Guarcello, Marianna; Maccarini, Laura; Cignoli, Federica; Setti, Stefania; Bazzano, Rosella; Roggi, Carla

    2008-02-01

    The present study evaluates eating habits and behaviors, and nutritional and food safety knowledge of a group of Italian adolescents. A dietary questionnaire previously constructed and tested was self-administered during school time. Each section was evaluated using a separate score. The study was carried out as a part of a nutritional surveillance project in the Aosta Valley Region, Northern Italy. Five hundred and thirty-two adolescent subjects, aged 15.4 +/- 0.7 years, attending the second year of secondary schools participated in the study. We evaluated eating habits, physical activity, meaning of healthy and unhealthy dietary habits and food, self-efficacy, barriers affecting healthy food choices, nutritional and food safety, weight, height, Body Mass Index (BMI). Only 37.0% of the sample have satisfactory eating habits; 18.5% have a very active lifestyle; only 8.6% have quite good nutritional knowledge, 2.4% have satisfactory food safety knowledge, although 43.7% have good hygiene practices. The results point out unhealthy behaviors influencing adolescents' eating habits and suggest which of these must be considered in order to develop tailored nutrition interventions, improving adolescents' consciousness aimed at adopting a healthy lifestyle.

  3. Eliciting and activating funds of knowledge in an environmental science community college classroom: An action research study

    NASA Astrophysics Data System (ADS)

    van Niel, John J.

    Many non-traditional students are currently underperforming in college and yet may have untapped knowledge and skills that could support their academic success if appropriately utilized. Previous practices that students experience as a part of their lives are what Gonzales and other researchers call "funds of knowledge" (FOK). There is ample evidence to show that utilization of students' FOK in K-12 instructional contexts can be beneficial. In contrast, little formal FOK research has been done with higher education students. To address this gap, this study explores how environmental college courses could be designed so as to better elicit and capitalize on students' FOK, with the ultimate goal of increasing student engagement and learning. More specifically, using an action research paradigm, I designed, implemented and studied an intervention in two sections of the required environmental science course I taught in Fall 2009 at the community college where I am employed. The intervention consisted of two phases: (1) eliciting FOK from the students enrolled in one section of the course through a draft survey, and (2) refining that survey tool in order to better elicit FOK, development of other methods of elicitation of FOK and activating (or incorporating) the FOK thus identified as relevant to enhance the learning experience of the students in both sections of the course. The designs of the intervention as well as data collection and analysis were informed by the following research questions: Q1. What are effective strategies for eliciting FOK that may be generalized to the practices of other college instructors? Q2. What relevant FOK do students bring to this class? Q3. What were instances where FOK were activated in the course? Q4. What are effective strategies for activating FOK that may be generalized to the practices of other college instructors? Q5. What evidence was there that students took up new practices due to the intervention? Data were collected from a

  4. Automated knowledge base development from CAD/CAE databases

    NASA Technical Reports Server (NTRS)

    Wright, R. Glenn; Blanchard, Mary

    1988-01-01

    Knowledge base development requires a substantial investment in time, money, and resources in order to capture the knowledge and information necessary for anything other than trivial applications. This paper addresses a means to integrate the design and knowledge base development process through automated knowledge base development from CAD/CAE databases and files. Benefits of this approach include the development of a more efficient means of knowledge engineering, resulting in the timely creation of large knowledge based systems that are inherently free of error.

  5. Safer obstetric anesthesia through education and mentorship: a model for knowledge translation in Rwanda.

    PubMed

    Livingston, Patricia; Evans, Faye; Nsereko, Etienne; Nyirigira, Gaston; Ruhato, Paulin; Sargeant, Joan; Chipp, Megan; Enright, Angela

    2014-11-01

    High rates of maternal mortality remain a widespread problem in the developing world. Skilled anesthesia providers are required for the safe conduct of Cesarean delivery and resuscitation during obstetrical crises. Few anesthesia providers in low-resource settings have access to continuing education. In Rwanda, anesthesia technicians with only three years of post-secondary training must manage complex maternal emergencies in geographically isolated areas. The purpose of this special article is to describe implementation of the SAFE (Safer Anesthesia From Education) Obstetric Anesthesia course in Rwanda, a three-day refresher course designed to improve obstetrical anesthesia knowledge and skills for practitioners in low-resource areas. In addition, we describe how the course facilitated the knowledge-to-action (KTA) cycle whereby a series of steps are followed to promote the uptake of new knowledge into clinical practice. The KTA cycle requires locally relevant teaching interventions and continuation of knowledge post intervention. In Rwanda, this meant carefully considering educational needs, revising curricula to suit the local context, employing active experiential learning during the SAFE Obstetric Anesthesia course, encouraging supportive relationships with peers and mentors, and using participant action plans for change, post-course logbooks, and follow-up interviews with participants six months after the course. During those interviews, participants reported improvements in clinical practice and greater confidence in coordinating team activities. Anesthesia safety remains challenged by resource limitations and resistance to change by health care providers who did not attend the course. Future teaching interventions will address the need for team training.

  6. 49 CFR 383.135 - Passing knowledge and skills tests.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 5 2013-10-01 2013-10-01 false Passing knowledge and skills tests. 383.135... COMMERCIAL DRIVER'S LICENSE STANDARDS; REQUIREMENTS AND PENALTIES Tests § 383.135 Passing knowledge and skills tests. (a) Knowledge tests. (1) To achieve a passing score on each of the knowledge tests, a...

  7. 49 CFR 383.135 - Passing knowledge and skills tests.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 5 2011-10-01 2011-10-01 false Passing knowledge and skills tests. 383.135... COMMERCIAL DRIVER'S LICENSE STANDARDS; REQUIREMENTS AND PENALTIES Tests § 383.135 Passing knowledge and skills tests. (a) Knowledge tests. (1) To achieve a passing score on each of the knowledge tests, a...

  8. 49 CFR 383.135 - Passing knowledge and skills tests.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 5 2014-10-01 2014-10-01 false Passing knowledge and skills tests. 383.135... COMMERCIAL DRIVER'S LICENSE STANDARDS; REQUIREMENTS AND PENALTIES Tests § 383.135 Passing knowledge and skills tests. (a) Knowledge tests. (1) To achieve a passing score on each of the knowledge tests, a...

  9. Variation in behavioral engagement during an active learning activity leads to differential knowledge gains in college students.

    PubMed

    LaDage, Lara D; Tornello, Samantha L; Vallejera, Jennilyn M; Baker, Emily E; Yan, Yue; Chowdhury, Anik

    2018-03-01

    There are many pedagogical techniques used by educators in higher education; however, some techniques and activities have been shown to be more beneficial to student learning than others. Research has demonstrated that active learning and learning in which students cognitively engage with the material in a multitude of ways result in better understanding and retention. The aim of the present study was to determine which of three pedagogical techniques led to improvement in learning and retention in undergraduate college students. Subjects partook in one of three different types of pedagogical engagement: hands-on learning with a model, observing someone else manipulate the model, and traditional lecture-based presentation. Students were then asked to take an online quiz that tested their knowledge of the new material, both immediately after learning the material and 2 wk later. Students who engaged in direct manipulation of the model scored higher on the assessment immediately after learning the material compared with the other two groups. However, there were no differences among the three groups when assessed after a 2-wk retention interval. Thus active learning techniques that involve direct interaction with the material can lead to learning benefits; however, how these techniques benefit long-term retention of the information is equivocal.

  10. The Relationship between Feelings-of-Knowing and Partial Knowledge for General Knowledge Questions

    PubMed Central

    Norman, Elisabeth; Blakstad, Oskar; Johnsen, Øivind; Martinsen, Stig K.; Price, Mark C.

    2016-01-01

    Feelings of knowing (FoK) are introspective self-report ratings of the felt likelihood that one will be able to recognize a currently unrecallable memory target. Previous studies have shown that FoKs are influenced by retrieved fragment knowledge related to the target, which is compatible with the accessibility hypothesis that FoK is partly based on currently activated partial knowledge about the memory target. However, previous results have been inconsistent as to whether or not FoKs are influenced by the accuracy of such information. In our study (N = 26), we used a recall-judge-recognize procedure where stimuli were general knowledge questions. The measure of partial knowledge was wider than those applied previously, and FoK was measured before rather than after partial knowledge. The accuracy of reported partial knowledge was positively related to subsequent recognition accuracy, and FoK only predicted recognition on trials where there was correct partial knowledge. Importantly, FoK was positively related to the amount of correct partial knowledge, but did not show a similar incremental relation with incorrect knowledge. PMID:27445950

  11. A survey of physicians and physiotherapists on physical activity promotion in Nigeria.

    PubMed

    Oyeyemi, Adewale L; Oyeyemi, Adetoyeje Y; Habib, Rahana Y; Usman, Rashida B; Sunday, Jasper U; Usman, Zubair

    2017-01-01

    Effective control of non-communicable diseases and promotion of population-wide physical activity participation require the active engagement of health professionals. Physiotherapists and physicians, as part of their practice, routinely screen and assess physical activity status, and recommend health enhancing physical activity participation for their patients. This study aims to compare Nigerian physiotherapists and physicians' knowledge of physical activity message, role perception and confidence, perceived feasibility and barriers, and overall disposition to promoting physical activity in their practice. A total of 153 physicians and 94 physiotherapists recruited from 10 government hospitals in five states in Northern Nigeria completed a standardized physical activity promotion questionnaire that elicited information on the knowledge of physical activity, role perception and confidence, feasibility, and barriers to physical activity promotion. Descriptive and inferential statistics were used to analyze the data. The physiotherapists and physicians were fairly knowledgeable on physical activity message (14.2 ± 2.1/20), reported minimal or little barrier to physical activity promotion (23.7 ± 3.1/30), perceived physical activity promotion as their role (13.0 ± 1.8/15), were confident in their ability to discuss and recommend physical activity promotion (7.6 ± 1.6/10) and believed promoting physical activity was feasible for them (15.6 ± 2.6/20). However, over 40% of the physiotherapists and physicians do not know the correct dosage of physical activity that could confer health benefits to patients. The physicians showed better overall disposition to physical activity promotion than the physiotherapists ( P  = 0.048), but more physiotherapists than the physicians believed ' it is part of their role to suggest to patients to increase their daily physical activity' (95.7% vs 88.2%, P  = 0.043) and were more 'confident in suggesting

  12. 24 CFR 1000.242 - When does the requirement for exemption from taxation apply to affordable housing activities?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... exemption from taxation apply to affordable housing activities? 1000.242 Section 1000.242 Housing and Urban... ACTIVITIES Indian Housing Plan (IHP) § 1000.242 When does the requirement for exemption from taxation apply to affordable housing activities? The requirement for exemption from taxation applies only to rental...

  13. 24 CFR 1000.242 - When does the requirement for exemption from taxation apply to affordable housing activities?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... exemption from taxation apply to affordable housing activities? 1000.242 Section 1000.242 Housing and Urban... ACTIVITIES Indian Housing Plan (IHP) § 1000.242 When does the requirement for exemption from taxation apply to affordable housing activities? The requirement for exemption from taxation applies only to rental...

  14. Students Fail to Transfer Knowledge of Chromosome Structure to Topics Pertaining to Cell Division

    PubMed Central

    Newman, Dina L.; Catavero, Christina M.; Wright, L. Kate

    2012-01-01

    Cellular processes that rely on knowledge of molecular behavior are difficult for students to comprehend. For example, thorough understanding of meiosis requires students to integrate several complex concepts related to chromosome structure and function. Using a grounded theory approach, we have unified classroom observations, assessment data, and in-depth interviews under the theory of knowledge transfer to explain student difficulties with concepts related to chromosomal behavior. In this paper, we show that students typically understand basic chromosome structure but do not activate cognitive resources that would allow them to explain macromolecular phenomena (e.g., homologous pairing during meiosis). To improve understanding of topics related to genetic information flow, we suggest that instructors use pedagogies and activities that prime students for making connections between chromosome structure and cellular processes. PMID:23222838

  15. Knowledge-driven information mining in remote-sensing image archives

    NASA Astrophysics Data System (ADS)

    Datcu, M.; Seidel, K.; D'Elia, S.; Marchetti, P. G.

    2002-05-01

    Users in all domains require information or information-related services that are focused, concise, reliable, low cost and timely and which are provided in forms and formats compatible with the user's own activities. In the current Earth Observation (EO) scenario, the archiving centres generally only offer data, images and other "low level" products. The user's needs are being only partially satisfied by a number of, usually small, value-adding companies applying time-consuming (mostly manual) and expensive processes relying on the knowledge of experts to extract information from those data or images.

  16. Lending a Helping Hand: Voluntary Engagement in Knowledge Sharing

    ERIC Educational Resources Information Center

    Mergel, Ines; Lazer, David; Binz-Scharf, Maria Christina

    2008-01-01

    Knowledge is essential for the functioning of every social system, especially for professionals in knowledge-intensive organisations. Since individuals do not possess all the work-related knowledge that they require, they turn to others in search for that knowledge. While prior research has mainly focused on antecedents and consequences of…

  17. Identifying knowledge-attitude-practice gaps to enhance HPV vaccine diffusion.

    PubMed

    Cohen, Elisia L; Head, Katharine J

    2013-01-01

    To examine differences in knowledge, attitudes, and related practices among adopters and nonadopters of the human papillomavirus (HPV) vaccine, the researchers conducted 83 in-depth interviews with 18- to 26-year-old women. The study identified knowledge-attitude-practice gaps in the context of the HPV vaccine to explain why diffusion of a preventive innovation (such as the HPV vaccine) requires targeted risk communication strategies in order to increase demand. Salient findings included similarities between vaccinated and unvaccinated women's lack of knowledge and uncertainties about HPV and cervical cancer. Vaccinated women who had no knowledge of HPV or no-risk/low-risk perceptions of HPV reported receiving vaccination, indicating HPV risk protection behavior could precede knowledge acquisition for vaccinated women. These vaccinated women identified an interpersonal network supportive of vaccination and reported supportive social influences. Among unvaccinated women, unsupportive vaccination attitudes included low perceived personal risk of HPV. In contrast, unvaccinated women often cited erroneous beliefs that HPV could be avoided by abstinence, monogamy, and knowledge of their partners' sexual history as reasons that the vaccine was not personally relevant. Unvaccinated women cited interpersonal influences that activated short- and long-term vaccination safety and efficacy concerns. Different levels of fear regarding the HPV vaccine may underlie (a) attitudinal differences between vaccinated and unvaccinated women in perceived vaccination value and (b) attitude-practice gaps.

  18. Active Mirror Predictive and Requirements Verification Software (AMP-ReVS)

    NASA Technical Reports Server (NTRS)

    Basinger, Scott A.

    2012-01-01

    This software is designed to predict large active mirror performance at various stages in the fabrication lifecycle of the mirror. It was developed for 1-meter class powered mirrors for astronomical purposes, but is extensible to other geometries. The package accepts finite element model (FEM) inputs and laboratory measured data for large optical-quality mirrors with active figure control. It computes phenomenological contributions to the surface figure error using several built-in optimization techniques. These phenomena include stresses induced in the mirror by the manufacturing process and the support structure, the test procedure, high spatial frequency errors introduced by the polishing process, and other process-dependent deleterious effects due to light-weighting of the mirror. Then, depending on the maturity of the mirror, it either predicts the best surface figure error that the mirror will attain, or it verifies that the requirements for the error sources have been met once the best surface figure error has been measured. The unique feature of this software is that it ties together physical phenomenology with wavefront sensing and control techniques and various optimization methods including convex optimization, Kalman filtering, and quadratic programming to both generate predictive models and to do requirements verification. This software combines three distinct disciplines: wavefront control, predictive models based on FEM, and requirements verification using measured data in a robust, reusable code that is applicable to any large optics for ground and space telescopes. The software also includes state-of-the-art wavefront control algorithms that allow closed-loop performance to be computed. It allows for quantitative trade studies to be performed for optical systems engineering, including computing the best surface figure error under various testing and operating conditions. After the mirror manufacturing process and testing have been completed, the

  19. Bodily Knowledge beyond Motor Skills and Physical Fitness: A Phenomenological Description of Knowledge Formation in Physical Training

    ERIC Educational Resources Information Center

    Parviainen, Jaana; Aromaa, Johanna

    2017-01-01

    Bodily knowledge has attracted significant attention within the humanities and other related fields over the last two decades. Although theoretical discussion on bodily knowledge in the context of physical education has been active over the past 10 years, these discussions lack clear conceptual analyses of bodily knowledge. Using a…

  20. From the greenhouse to the field: Cultivation requirements of Arizona cliffrose (Purshia subintegra)

    Treesearch

    Joanne E. Baggs; Joyce Maschinski

    2001-01-01

    Central to the conservation of the federally endangered Purshia subintegra (Arizona cliffrose) is development of an understanding of its cultivation requirements. This knowledge will enable us to augment declining or threatened populations as well as preserve genotypes impacted by human activities. We studied seed and stem cutting propagation of P. subintegra. The...

  1. Evaluation of pharmacy students' knowledge and perceptions of pharmacogenetics before and after a simulation activity.

    PubMed

    Patel, Radha V; Chudow, Melissa; Vo, Teresa T; Serag-Bolos, Erini S

    The purpose of this study was to evaluate students' knowledge and perceptions of the clinical application of pharmacogenetics through a simulation activity and to assess communication of pharmacogenetic-guided treatment recommendations utilizing standardized patients. Third-year students in the four-year doctor of pharmacy (PharmD) program at University of South Florida College of Pharmacy completed a pharmacogenetics simulation involving a patient case review, interpretation of pharmacogenetic test results, completion of a situation, background, assessment, recommendation (SBAR) note with drug therapy recommendations, and patient counseling. Voluntary assessments were completed before and after the simulation, which included demographics, knowledge, and perceptions of students' ability to interpret and communicate pharmacogenetic results. Response rates for the pre- and post-simulation assessments were 109 (98%) and 104 (94%), respectively. Correct responses in application-type questions improved after the simulation (74%) compared to before the simulation (44%, p < 0.01). Responses to perception questions shifted towards "strongly agree" or "agree" after the simulation (p < 0.01). The simulation gave students an opportunity to apply pharmacogenetics knowledge and allowed them to gain an appreciation of pharmacists' roles within the pharmacogenetics field. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Awareness of knowledge and practice regarding physical activity: A population-based prospective, observational study among students in Nanjing, China

    PubMed Central

    Xiang, Dandan; Wang, Zhiyong; Ye, Qing; Ware, Robert S.

    2017-01-01

    Background Physical activity (PA) promotion has proven effectiveness in preventing childhood obesity. Increasing children’s health knowledge is the most frequently used approach in PA intervention programs targeting childhood obesity prevention. However, little is known about the specific association between the change in a child’s knowledge awareness and their PA practice. Methods A one-year follow-up study was conducted among primary and junior high school students in Nanjing, China. At baseline students’ knowledge of healthy behavior, and their PA levels, were assessed. Students who were unaware of the association between PA and obesity were followed for one academic year. After nine-months their knowledge and PA levels were re-measured using the same validated questionnaire. Mixed effects regression models were used to estimate the relationship between awareness of knowledge about the link between PA and obesity and PA changes. Results Of the 1899 students who were unaware of the association between PA and obesity at baseline, 1859 (follow-up rate = 97.9%) were successfully followed-up. After nine months 1318 (70.9%) participants had become aware of PA-obesity association. Compared to their counterparts who remained unaware, students who became aware of the PA-obesity association were more likely to increase both the frequency (odds ratio (OR) = 1.34, 95%CI = 1.09, 1.64) and duration (OR = 1.34, 95%CI = 1.09, 1.65) of PA, after adjusting for potentially confounding variables. Conclusion Becoming aware of the known link between PA and obesity led to positive behavior modification regarding PA in this cohort of Chinese students. This is of particular importance that knowledge disimination and health education may be a useful approach for population-based physical activity promotion aiming at childhood obesity prevention in China. PMID:28622354

  3. Academic Libraries and Copyright: Do Librarians Really Have the Required Knowledge?

    ERIC Educational Resources Information Center

    Fernández-Molina, Juan-Carlos; Moraes, João Batista E.; Guimarães, José Augusto C.

    2017-01-01

    A solid professional performance on the part of academic librarians at present calls for adequate knowledge about copyright law, not only for the development of their own tasks without infringing the law, but also to guide and provide pertinent advice for library users (faculty and students). This paper presents the results of an online survey of…

  4. 77 FR 12364 - Agency Information Collection; Activity Under OMB Review: Reporting Required for International...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-29

    ... supplemental data for the International Civil Aviation Organization (ICAO). Comments are requested concerning.... 2138-0039. Title: Reporting Required for International Civil Aviation Organization (ICAO). Form No...-0002] Agency Information Collection; Activity Under OMB Review: Reporting Required for International...

  5. Specific Sirt1 Activator-mediated Improvement in Glucose Homeostasis Requires Sirt1-Independent Activation of AMPK.

    PubMed

    Park, Sung-Jun; Ahmad, Faiyaz; Um, Jee-Hyun; Brown, Alexandra L; Xu, Xihui; Kang, Hyeog; Ke, Hengming; Feng, Xuesong; Ryall, James; Philp, Andrew; Schenk, Simon; Kim, Myung K; Sartorelli, Vittorio; Chung, Jay H

    2017-04-01

    The specific Sirt1 activator SRT1720 increases mitochondrial function in skeletal muscle, presumably by activating Sirt1. However, Sirt1 gain of function does not increase mitochondrial function, which raises a question about the central role of Sirt1 in SRT1720 action. Moreover, it is believed that the metabolic effects of SRT1720 occur independently of AMP-activated protein kinase (AMPK), an important metabolic regulator that increases mitochondrial function. Here, we show that SRT1720 activates AMPK in a Sirt1-independent manner and SRT1720 activates AMPK by inhibiting a cAMP degrading phosphodiesterase (PDE) in a competitive manner. Inhibiting the cAMP effector protein Epac prevents SRT1720 from activating AMPK or Sirt1 in myotubes. Moreover, SRT1720 does not increase mitochondrial function or improve glucose tolerance in AMPKα2 knockout mice. Interestingly, weight loss induced by SRT1720 is not sufficient to improve glucose tolerance. Therefore, contrary to current belief, the metabolic effects produced by SRT1720 require AMPK, which can be activated independently of Sirt1. Published by Elsevier B.V.

  6. Taking knowledge users' knowledge needs into account in health: an evidence synthesis framework.

    PubMed

    Wickremasinghe, Deepthi; Kuruvilla, Shyama; Mays, Nicholas; Avan, Bilal Iqbal

    2016-05-01

    The increased demand for evidence-based practice in health policy in recent years has provoked a parallel increase in diverse evidence-based outputs designed to translate knowledge from researchers to policy makers and practitioners. Such knowledge translation ideally creates user-friendly outputs, tailored to meet information needs in a particular context for a particular audience. Yet matching users' knowledge needs to the most suitable output can be challenging. We have developed an evidence synthesis framework to help knowledge users, brokers, commissioners and producers decide which type of output offers the best 'fit' between 'need' and 'response'. We conducted a four-strand literature search for characteristics and methods of evidence synthesis outputs using databases of peer reviewed literature, specific journals, grey literature and references in relevant documents. Eight experts in synthesis designed to get research into policy and practice were also consulted to hone issues for consideration and ascertain key studies. In all, 24 documents were included in the literature review. From these we identified essential characteristics to consider when planning an output-Readability, Relevance, Rigour and Resources-which we then used to develop a process for matching users' knowledge needs with an appropriate evidence synthesis output. We also identified 10 distinct evidence synthesis outputs, classifying them in the evidence synthesis framework under four domains: key features, utility, technical characteristics and resources, and in relation to six primary audience groups-professionals, practitioners, researchers, academics, advocates and policy makers. Users' knowledge needs vary and meeting them successfully requires collaborative planning. The Framework should facilitate a more systematic assessment of the balance of essential characteristics required to select the best output for the purpose. © The Author 2015. Published by Oxford University Press.

  7. Motivation in a Computer-Supported Collaborative Learning Scenario and Its Impact on Learning Activities and Knowledge Acquisition

    ERIC Educational Resources Information Center

    Schoor, Cornelia; Bannert, Maria

    2011-01-01

    Addressing a drawback in current research on computer-supported collaborative learning (CSCL), this study investigated the influence of motivation on learning activities and knowledge acquisition during CSCL. Participants' (N = 200 university students) task was to develop a handout for which they had first an individual preparing phase followed by…

  8. Physical Education Teacher Education Students' Knowledge, Perceptions and Experiences of Promoting Healthy, Active Lifestyles in Secondary Schools

    ERIC Educational Resources Information Center

    Harris, Jo

    2014-01-01

    Background: Physical education teacher education (PETE) offers a context for students to learn about the promotion of active lifestyles in secondary schools through their interactions and experiences during the teacher education process. However, previous studies have found low levels of health-related fitness knowledge amongst PETE students,…

  9. Enhancing Knowledge Sharing and Research Collaboration among Academics: The Role of Knowledge Management

    ERIC Educational Resources Information Center

    Tan, Christine Nya-Ling

    2016-01-01

    Although knowledge sharing (KS) has been acknowledged as important, universities face issues that may hinder active sharing among its faculty members such as the absence of trust among its members or insufficient incentives rewarded to those who deserved it. The aim of this research is to focus on the impact of knowledge management (KM) factors in…

  10. 77 FR 8148 - Anti-Money Laundering Program and Suspicious Activity Report Filing Requirements for Residential...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-14

    ... 1506-AB02 Anti-Money Laundering Program and Suspicious Activity Report Filing Requirements for... finance companies for the purpose of requiring them to establish anti-money laundering programs and report... Secretary is authorized to impose anti-money laundering (``AML'') program requirements on financial...

  11. Constructing Cardiovascular Fitness Knowledge in Physical Education

    ERIC Educational Resources Information Center

    Zhang, Tan; Chen, Ang; Chen, Senlin; Hong, Deockki; Loflin, Jerry; Ennis, Catherine

    2014-01-01

    In physical education, it has become necessary for children to learn kinesiological knowledge for understanding the benefits of physical activity and developing a physically active lifestyle. This study was conducted to determine the extent to which cognitive assignments about healthful living and fitness contributed to knowledge growth on…

  12. Health, lifestyle, belief and knowledge differences between two ethnic groups with specific reference to tobacco, diet and physical activity.

    PubMed

    Anthony, Denis; Baggott, Rob; Tanner, Judith; Jones, Kathryn; Evans, Hala; Perkins, Gill; Palmer, Hilary

    2012-11-01

      To compare physical activity levels, body mass index, habitual diet, tobacco use and prevalence of non-communicable disease between the two ethnic groups and to identify predictors for differences between groups.   Tobacco use, poor diet and physical inactivity are major lifestyle risk factors for chronic cardiovascular diseases, certain cancers, diabetes and chronic lung diseases. There are higher risk and incidence of these diseases in some ethnic groups, for example Asians have higher incidence of diabetes.   Cross sectional survey.   Cross sectional survey of Asians of Indian descent and white British adults conducted between October-December 2009. Main outcome variables were lifestyle behaviours and BMI. Self-reported disease diagnosis was also collected. In a regression analysis, predictors of outcome variables were demographic variables and beliefs/attitudes/knowledge towards lifestyle behaviours.   Body mass index, tobacco use and non-communicable disease (except diabetes) were lower in Indians. Indians reported lower physical activity levels and greater salt use than Whites. Tobacco use was higher in Whites, but knowledge, attitudes and beliefs were similar between Whites and Indians.   Health risk behaviour and morbidity are different between the two ethnic groups. Gender, age, educational level, beliefs, attitudes and knowledge do not explain these differences. Health promotion that aims to improve knowledge will probably not work and innovative methods are needed to improve health in high risk groups. © 2012 Blackwell Publishing Ltd.

  13. 42 CFR 495.314 - Activities required to receive an incentive payment.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Activities required to receive an incentive payment. 495.314 Section 495.314 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION STANDARDS FOR THE ELECTRONIC HEALTH RECORD...

  14. Sexually active older Australian's knowledge of sexually transmitted infections and safer sexual practices.

    PubMed

    Lyons, Anthony; Heywood, Wendy; Fileborn, Bianca; Minichiello, Victor; Barrett, Catherine; Brown, Graham; Hinchliff, Sharron; Malta, Sue; Crameri, Pauline

    2017-06-01

    Rates of sexually transmitted infections (STIs) are rising among older Australians. We conducted a large survey of older people's knowledge of STIs and safer sexual practices. A total of 2,137 Australians aged 60 years and older completed the survey, which included 15 questions assessing knowledge of STIs and safer sexual practices. We examined both levels of knowledge and factors associated with an overall knowledge score. In total, 1,652 respondents reported having sex in the past five years and answered all knowledge questions. This group had good general knowledge but poorer knowledge in areas such as the protection offered by condoms and potential transmission modes for specific STIs. Women had better knowledge than men. Men in their 60s, men with higher education levels, and men who thought they were at risk of STIs reported better knowledge than other men. Knowledge was also better among men and women who had been tested for STIs or reported 'other' sources of knowledge on STIs. Many older Australians lack knowledge of STIs and safer sexual practices. Implications for public health: To reverse current trends toward increasing STI diagnoses in this population, policies and education campaigns aimed at improving knowledge levels may need to be considered. © 2017 The Authors.

  15. Regulatory requirements for genotoxicity assessment of plant protection product active ingredients, impurities, and metabolites.

    PubMed

    Booth, Ewan D; Rawlinson, Paul J; Maria Fagundes, Priscila; Leiner, Kevin A

    2017-06-01

    Active ingredients in plant protection products are subject to rigorous safety assessment during their development, including assessment of genotoxicity. Plant protection products are used for agriculture in multiple regions and for the registration of active ingredients it is necessary to satisfy the data requirements of these different regions. There are no overarching global agreements on which genotoxicity studies need to be conducted to satisfy the majority of regulatory authorities. The implementation of new OECD guidelines for the in vitro micronucleus, transgenic rodent somatic and germ cell gene mutation and in vivo comet assays, as well as the revision of a number of other OECD test guidelines has resulted in some changes to data requirements. This review describes the genotoxicity data requirements for chemical active ingredients as well as biologicals, microbials, ground water metabolites, metabolites, and impurities in a number of regions. Similarities and differences are highlighted. Environ. Mol. Mutagen. 58:325-344, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  16. Designing for knowledge: bridging socio-hydrological monitoring and beyond

    NASA Astrophysics Data System (ADS)

    Mao, F.; Clark, J.; Buytaert, W.; Ochoa-Tocachi, B. F.; Hannah, D. M.

    2016-12-01

    Many methods and applications have been developed to research socio-hydrological systems, such as participatory monitoring, environmental big data processing and sensor network data transmission. However, these data-centred activities are insufficient to guarantee successful knowledge co-generation, decision making or governance. This research suggests a shift of attentions in designing socio-hydrological monitoring tools, from designing for data to designing for knowledge (DfK). Compared to the former strategy, DfK has at least three features as follows. (1) Why monitor? DfK demands the data produced by the newly introduced monitoring application to have potentials to generate socio-hydrological knowledge that supports decision making or management. It means that when designing a monitoring tool, we should not only answer how to collect data, but also questions such as how to best use the collected data in the form of knowledge. (2) What is the role of monitoring? DfK admits that the socio-hydrological data and knowledge generated by monitoring is just one of many kinds to support decision making and management. It means that the importance of monitoring and scientific evidence should not be overestimated, and knowledge cogeneration and synthesis should be considered in advance in the monitoring design process. (3) Who participate? DfK implies a wider engagement of stakeholders, which is not restricted between volunteers as data collectors and providers, and scientist and researcher communities as main data users. It requires a broader consideration of users, including not only data collectors, processors and interpreters, but also local and indigenous knowledge providers, and decision makers who use the knowledge and data. In summary, this research proposes a knowledge-centred strategy in designing participatory socio-hydrological monitoring tools, in order to make monitoring more useful and effective.

  17. The Effects of an Infant-Feeding Classroom Activity on the Breast-Feeding Knowledge and Intentions of Adolescents

    ERIC Educational Resources Information Center

    Walsh, Audrey; Moseley, Jane; Jackson, Winston

    2008-01-01

    This study examined the impact of an infant-feeding classroom activity on the breast-feeding knowledge and intentions of adolescents living in Nova Scotia, Canada. One hundred twenty-one students attending two high schools were administered one pretest and two posttest questionnaires. Students were arbitrarily assigned to a control or intervention…

  18. Changes in Men's Physical Activity and Healthy Eating Knowledge and Behavior as a Result of Program Exposure: Findings From the Workplace POWERPLAY Program.

    PubMed

    Caperchione, Cristina M; Stolp, Sean; Bottorff, Joan L; Oliffe, John L; Johnson, Steven T; Seaton, Cherisse; Sharp, Paul; Jones-Bricker, Margaret; Lamont, Sonia; Errey, Sally; Healy, Theresa; Medhurst, Kerensa; Christian, Holly; Klitch, Megan

    2016-12-01

    The purpose of this study was to examine changes in physical activity and healthy eating knowledge and behaviors associated with the level of exposure to POWERPLAY, a men-centered workplace health promotion program. This study is based on a quasi-experimental prepost design. Using a computer assisted telephone interview survey, data regarding program exposure and physical activity and health eating knowledge and behaviors were collected from men (N = 103) in 4 workplaces. Exposure scores were calculated and participants were categorized as having low (n = 54) or high exposure (n = 49) to POWERPLAY. Compared with the low exposure group, those reporting high exposure scored significantly higher on physical activity knowledge (F (1, 99) =14.17, P < .001, eta2 = .125) and health eating knowledge (F (1, 99) =14.37, P = .001, eta2 = .111). The high exposure group also reported significantly more minutes walked place to place (F (2, 206) = 3.91, P = .022, eta 2 = .037) and on minutes walked for leisure (F (2, 230) = 3.08, P = .048, eta 2 = .026). POWERPLAY shows significant promise as a workplace health promotion approach and may have an even greater impact when program exposure is augmented with environmental and policy changes.

  19. A Discussion of Knowledge Based Design

    NASA Technical Reports Server (NTRS)

    Wood, Richard M.; Bauer, Steven X. S.

    1999-01-01

    A discussion of knowledge and Knowledge- Based design as related to the design of aircraft is presented. The paper discusses the perceived problem with existing design studies and introduces the concepts of design and knowledge for a Knowledge- Based design system. A review of several Knowledge-Based design activities is provided. A Virtual Reality, Knowledge-Based system is proposed and reviewed. The feasibility of Virtual Reality to improve the efficiency and effectiveness of aerodynamic and multidisciplinary design, evaluation, and analysis of aircraft through the coupling of virtual reality technology and a Knowledge-Based design system is also reviewed. The final section of the paper discusses future directions for design and the role of Knowledge-Based design.

  20. Conceptualisation of knowledge construction in community service-learning programmes in nursing education.

    PubMed

    Mthembu, Sindi Z; Mtshali, Fikile G

    2013-01-01

    Practices in higher education have been criticised for not developing and preparing students for the expertise required in real environments. Literature reports that educational programmes tend to favour knowledge conformation rather than knowledge construction; however, community service learning (CSL) is a powerful pedagogical strategy that encourages students to make meaningful connections between the content in the classroom and real-life experiences as manifested by the communities. Through CSL, learning is achieved by the active construction of knowledge supported by multiple perspectives within meaningful real contexts, and the social interactions amongst students are seen to play a critical role in the processes of learning and cognition. This article reflects facilitators’ perspective of the knowledge construction process as used with students doing community service learning in basic nursing programmes. The aim of this article was to conceptualise the phenomenon of knowledge construction and thereby provide educators with a shared meaning and common understanding, and to analyse the interaction strategies utilised by nurse educators in the process of knowledge construction in community service-learning programmes in basic nursing education. A qualitative research approach based on a grounded theory research design was used in this article. Two nursing education institutions were purposively selected. Structured interviews were conducted with 16 participants. The results revealed that the knowledge construction in community service-learning programmes is conceptualised as having specific determinants, including the use of authentic health-related problems, academic coaching through scaffolding, academic discourse-dialogue, interactive learning in communities of learners, active learning, continuous reflection as well as collaborative and inquiry-based learning. Upon completion of an experience, students create and test generated knowledge in different

  1. V-ATPase proton pumping activity is required for adult zebrafish appendage regeneration.

    PubMed

    Monteiro, Joana; Aires, Rita; Becker, Jörg D; Jacinto, António; Certal, Ana C; Rodríguez-León, Joaquín

    2014-01-01

    The activity of ion channels and transporters generates ion-specific fluxes that encode electrical and/or chemical signals with biological significance. Even though it is long known that some of those signals are crucial for regeneration, only in recent years the corresponding molecular sources started to be identified using mainly invertebrate or larval vertebrate models. We used adult zebrafish caudal fin as a model to investigate which and how ion transporters affect regeneration in an adult vertebrate model. Through the combined use of biophysical and molecular approaches, we show that V-ATPase activity contributes to a regeneration-specific H+ ef`flux. The onset and intensity of both V-ATPase expression and H+ efflux correlate with the different regeneration rate along the proximal-distal axis. Moreover, we show that V-ATPase inhibition impairs regeneration in adult vertebrate. Notably, the activity of this H+ pump is necessary for aldh1a2 and mkp3 expression, blastema cell proliferation and fin innervation. To the best of our knowledge, this is the first report on the role of V-ATPase during adult vertebrate regeneration.

  2. V-ATPase Proton Pumping Activity Is Required for Adult Zebrafish Appendage Regeneration

    PubMed Central

    Monteiro, Joana; Aires, Rita; Becker, Jörg D.; Jacinto, António; Certal, Ana C.; Rodríguez-León, Joaquín

    2014-01-01

    The activity of ion channels and transporters generates ion-specific fluxes that encode electrical and/or chemical signals with biological significance. Even though it is long known that some of those signals are crucial for regeneration, only in recent years the corresponding molecular sources started to be identified using mainly invertebrate or larval vertebrate models. We used adult zebrafish caudal fin as a model to investigate which and how ion transporters affect regeneration in an adult vertebrate model. Through the combined use of biophysical and molecular approaches, we show that V-ATPase activity contributes to a regeneration-specific H+ ef`flux. The onset and intensity of both V-ATPase expression and H+ efflux correlate with the different regeneration rate along the proximal-distal axis. Moreover, we show that V-ATPase inhibition impairs regeneration in adult vertebrate. Notably, the activity of this H+ pump is necessary for aldh1a2 and mkp3 expression, blastema cell proliferation and fin innervation. To the best of our knowledge, this is the first report on the role of V-ATPase during adult vertebrate regeneration. PMID:24671205

  3. Pib2 and the EGO complex are both required for activation of TORC1.

    PubMed

    Varlakhanova, Natalia V; Mihalevic, Michael J; Bernstein, Kara A; Ford, Marijn G J

    2017-11-15

    The TORC1 complex is a key regulator of cell growth and metabolism in Saccharomyces cerevisiae The vacuole-associated EGO complex couples activation of TORC1 to the availability of amino acids, specifically glutamine and leucine. The EGO complex is also essential for reactivation of TORC1 following rapamycin-induced growth arrest and for its distribution on the vacuolar membrane. Pib2, a FYVE-containing phosphatidylinositol 3-phosphate (PI3P)-binding protein, is a newly discovered and poorly characterized activator of TORC1. Here, we show that Pib2 is required for reactivation of TORC1 following rapamycin-induced growth arrest. Pib2 is required for EGO complex-mediated activation of TORC1 by glutamine and leucine as well as for redistribution of Tor1 on the vacuolar membrane. Therefore, Pib2 and the EGO complex cooperate to activate TORC1 and connect phosphoinositide 3-kinase (PI3K) signaling and TORC1 activity. © 2017. Published by The Company of Biologists Ltd.

  4. Maintenance of neuronal size gradient in MNTB requires sound-evoked activity.

    PubMed

    Weatherstone, Jessica H; Kopp-Scheinpflug, Conny; Pilati, Nadia; Wang, Yuan; Forsythe, Ian D; Rubel, Edwin W; Tempel, Bruce L

    2017-02-01

    The medial nucleus of the trapezoid body (MNTB) is an important source of inhibition during the computation of sound location. It transmits fast and precisely timed action potentials at high frequencies; this requires an efficient calcium clearance mechanism, in which plasma membrane calcium ATPase 2 (PMCA2) is a key component. Deafwaddler ( dfw 2J ) mutant mice have a null mutation in PMCA2 causing deafness in homozygotes ( dfw 2J / dfw 2J ) and high-frequency hearing loss in heterozygotes (+/ dfw 2J ). Despite the deafness phenotype, no significant differences in MNTB volume or cell number were observed in dfw 2J homozygous mutants, suggesting that PMCA2 is not required for MNTB neuron survival. The MNTB tonotopic axis encodes high to low sound frequencies across the medial to lateral dimension. We discovered a cell size gradient along this axis: lateral neuronal somata are significantly larger than medially located somata. This size gradient is decreased in +/ dfw 2J and absent in dfw 2J / dfw 2J The lack of acoustically driven input suggests that sound-evoked activity is required for maintenance of the cell size gradient. This hypothesis was corroborated by selective elimination of auditory hair cell activity with either hair cell elimination in Pou4f3 DTR mice or inner ear tetrodotoxin (TTX) treatment. The change in soma size was reversible and recovered within 7 days of TTX treatment, suggesting that regulation of the gradient is dependent on synaptic activity and that these changes are plastic rather than permanent. NEW & NOTEWORTHY Neurons of the medial nucleus of the trapezoid body (MNTB) act as fast-spiking inhibitory interneurons within the auditory brain stem. The MNTB is topographically organized, with low sound frequencies encoded laterally and high frequencies medially. We discovered a cell size gradient along this axis: lateral neurons are larger than medial neurons. The absence of this gradient in deaf mice lacking plasma membrane calcium ATPase 2

  5. Sss1p Is Required to Complete Protein Translocon Activation*

    PubMed Central

    Wilkinson, Barrie M.; Brownsword, Judith K.; Mousley, Carl J.; Stirling, Colin J.

    2010-01-01

    Protein translocation across the endoplasmic reticulum membrane occurs at the Sec61 translocon. This has two essential subunits, the channel-forming multispanning membrane protein Sec61p/Sec61α and the tail-anchored Sss1p/Sec61γ, which has been proposed to “clamp” the channel. We have analyzed the function of Sss1p using a series of domain mutants and found that both the cytosolic and transmembrane clamp domains of Sss1p are essential for protein translocation. Our data reveal that the cytosolic domain is required for Sec61p interaction but that the transmembrane clamp domain is required to complete activation of the translocon after precursor targeting to Sec61p. PMID:20709746

  6. The Use of Clinical Interviews to Develop Inservice Secondary Science Teachers' Nature of Science Knowledge and Assessment of Student Nature of Science Knowledge

    ERIC Educational Resources Information Center

    Peters-Burton, Erin E.

    2013-01-01

    To fully incorporate nature of science knowledge into classrooms, teachers must be both proficient in their own nature of science knowledge, but also skillful in translating their knowledge into a learning environment which assesses student knowledge. Twenty-eight inservice teachers enrolled in a graduate course which in part required a clinical…

  7. Eating for 1, Healthy and Active for 2; feasibility of delivering novel, compact training for midwives to build knowledge and confidence in giving nutrition, physical activity and weight management advice during pregnancy

    PubMed Central

    2014-01-01

    Background Women in Wales are more likely to be obese in pregnancy than in any other United Kingdom (UK) country. Midwives are ideally placed to explore nutrition, physical activity and weight management concerns however qualitative studies indicate they lack confidence in raising the sensitive issue of weight. Acknowledging this and the reality of finite time and resources, this study aimed to deliver compact training on nutrition, physical activity and weight management during pregnancy to increase the knowledge and confidence of midwives in this subject. Methods A compact training package for midwives was developed comprising of evidence based nutrition, physical activity and weight management guidance for pregnancy. Training was promoted via midwifery leads and delivered within the Health Board. Questionnaires based on statements from national public health guidance were used to assess changes in self-reported knowledge and confidence pre and post training. Descriptive statistics were applied and 95% confidence intervals were calculated. Results 43 midwives registered for training, 32 (74%) attended and completed the questionnaires. Although, pre training knowledge and confidence varied between participants, statistically significant improvements in self-reported knowledge and confidence were observed post training. 97% indicated knowledge of pregnancy specific food and nutrition messages as ‘better’ (95% CI 85 to 100), as opposed to 3% stating ‘stayed the same’ – 60% stated ‘much better’. 83% indicated confidence to explain the risks of raised BMI in pregnancy was either ‘much’ or ‘somewhat better’ (95% CI 66 to 93), as opposed to 17% stating ‘stayed the same’. 89% indicated confidence to discuss eating habits and physical activity was ‘much’ or ‘somewhat better’ (95% CI 73 to 97) as opposed to 11% stating ‘stayed the same’. Emergent themes highlighted that training was positively received and relevant to midwifery

  8. On the Limitations of Biological Knowledge

    PubMed Central

    Dougherty, Edward R; Shmulevich, Ilya

    2012-01-01

    Scientific knowledge is grounded in a particular epistemology and, owing to the requirements of that epistemology, possesses limitations. Some limitations are intrinsic, in the sense that they depend inherently on the nature of scientific knowledge; others are contingent, depending on the present state of knowledge, including technology. Understanding limitations facilitates scientific research because one can then recognize when one is confronted by a limitation, as opposed to simply being unable to solve a problem within the existing bounds of possibility. In the hope that the role of limiting factors can be brought more clearly into focus and discussed, we consider several sources of limitation as they apply to biological knowledge: mathematical complexity, experimental constraints, validation, knowledge discovery, and human intellectual capacity. PMID:23633917

  9. 75 FR 74066 - Agency Information Collection Activities: Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-30

    .... Physical Activity, which includes measures related to change in knowledge, attitudes, behavior, and levels... hours BMI 50 30 1,500 .10 150 Nutrition 50 30 1,500 .20 300 Physical Activity 50 30 1,500 .20 300... Information Collection Activities: Proposed Collection: Comment Request In compliance with the requirement for...

  10. Nutrition knowledge, beliefs and dietary habits among elderly people in Nizwa, Oman: implications for policy.

    PubMed

    Al Riyami, A; Al Hadabi, S; Abd El Aty, M A; Al Kharusi, H; Morsi, M; Jaju, S

    2010-08-01

    The nutritional needs of the ageing population require special attention. We undertook a cross-sectional, community-based, household survey in Nizwa wilayat, Oman to study nutrition-related knowledge and beliefs and self-reported dietary habits among a sample of elderly people. The response rate for the household interview was 99.3% from a total sample of 2041. About 45% of the elderly were overweight or obese. Overall we found poor knowledge of nutrition plus some nutritional imbalances and low levels of physical activity. Significant sex differences existed in elderly peoples' nutritional knowledge, consumption of fluids, milk and sweets, use of dietary regimens and experience of appetite change. The findings warrant reorientation of the existing health promotion strategy for the elderly.

  11. Optimization of knowledge sharing through multi-forum using cloud computing architecture

    NASA Astrophysics Data System (ADS)

    Madapusi Vasudevan, Sriram; Sankaran, Srivatsan; Muthuswamy, Shanmugasundaram; Ram, N. Sankar

    2011-12-01

    Knowledge sharing is done through various knowledge sharing forums which requires multiple logins through multiple browser instances. Here a single Multi-Forum knowledge sharing concept is introduced which requires only one login session which makes user to connect multiple forums and display the data in a single browser window. Also few optimization techniques are introduced here to speed up the access time using cloud computing architecture.

  12. Changes in Student Knowledge and Views of Geohazards, Societal Risks, and Monitoring at Active Plate Boundaries Using a Data-Rich Curriculum

    NASA Astrophysics Data System (ADS)

    Selkin, P. A.; Goodell, L. P.; Teasdale, R.

    2015-12-01

    The "Living on the Edge: Building Resilient Societies on Active Plate Margins" curriculum consists of six data-rich activities, each intended for a 50-minute class, in which students assess risk at active plate boundaries due to earthquakes and volcanoes. Developed as part of the InTeGrate NSF STEP Center the peer-reviewed, publically available materials (http://serc.carleton.edu/104296) have been used at several institutions in diverse classroom settings including small laboratory sections, large lecture courses, medium-sized upper division courses and professional development programs for middle and high school teachers. Pre- and post-instruction surveys measured content knowledge and geoscience literacy, self-efficacy in using geologic data to assess hazards and risk, and attitudes towards the value of monitoring plate margins. The activities have overall positive effects on knowledge of geohazard concepts. Views about the value of scientific practice also became more positive: 74% of students indicated they "agree" or "strongly agree" that monitoring geologic activity has value to them personally (even if they don't live on an active plate margin) and 94% indicated that such monitoring is valuable to society. Most became more confident in evaluating geologic hazard and risk (>60% of students self-described increased confidence by one or more Likert levels). Student knowledge of both the types and limits of data in forecasting geological hazards and their effects also improved. However, attitudes toward sustainability and geoscience careers did not change. Learning and attitudinal improvements are true for all classroom types, but the degree of change varies with class size and the amount of time spent on activities. Learning data and instructor feedback suggest that interactive classroom activities that use real-world data to address societally relevant issues increase student learning and enhance students' ability to synthesize scientific information.

  13. Methods to Succeed in Effective Knowledge Translation in Clinical Practice.

    PubMed

    Kitson, Alison L; Harvey, Gillian

    2016-05-01

    To explore the evidence around facilitation as an intervention for the successful implementation of new knowledge into clinical practice. The revised version of the Promoting Action on Research Implementation in Health Services (PARIHS) framework, called the integrated or i-PARIHS framework, is used as the explanatory framework. This framework posits that evidence is a multidimensional construct embedded within innovation and operationalized by clinicians (individuals and within teams), working across multiple layers of context. Facilitation is the active ingredient that promotes successful implementation. An emerging body of evidence supports facilitation as a mechanism to getting new knowledge into clinical practice. Facilitation roles are divided into beginner, experienced, and expert facilitators. Facilitators can be internal or external to the organization they work in, and their skills and attributes complement other knowledge translation (KT) roles. Complex KT projects require facilitators who are experienced in implementation methods. Facilitation is positioned as the active ingredient to effectively introduce new knowledge into a clinical setting. Levels of facilitation experience are assessed in relation to the complexity of the KT task. Three core facilitation roles are identified, and structured interventions are established taking into account the nature and novelty of the evidence, the receptiveness of the clinicians, and the context or setting where the new evidence is to be introduced. Roles such as novice, experienced, and expert facilitators have important and complementary parts to play in enabling the successful translation of evidence into everyday practice in order to provide effective care for patients. © 2016 Sigma Theta Tau International.

  14. Understanding How Students Perceive the Role of Ideas for Their Knowledge Work in a Knowledge-Building Environment

    ERIC Educational Resources Information Center

    Hong, Huang-Yao; Chiu, Chieh-Hsin

    2016-01-01

    This study explored how students viewed the role of ideas for knowledge work and how such a view was related to their inquiry activities. Data mainly came from students' online interaction logs, group discussion and inquiry, and a survey concerning the role of ideas for knowledge work. The findings suggest that knowledge building was conducive to…

  15. Sea Stories: A Collaborative Tool for Articulating Tactical Knowledge.

    ERIC Educational Resources Information Center

    Radtke, Paul H.; Frey, Paul R.

    Having subject matter experts (SMEs) identify the skills and knowledge to be taught is among the more difficult and time-consuming steps in the training development process. A procedure has been developed for identifying specific tactical decision-making knowledge requirements and translating SME knowledge into appropriate multimedia…

  16. 18 CFR 376.209 - Procedures during periods of emergency requiring activation of the Continuity of Operations Plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... periods of emergency requiring activation of the Continuity of Operations Plan. 376.209 Section 376.209... GENERAL RULES ORGANIZATION, MISSION, AND FUNCTIONS; OPERATIONS DURING EMERGENCY CONDITIONS Commission Operation During Emergency Conditions § 376.209 Procedures during periods of emergency requiring activation...

  17. Mechanical knowledge does matter to tool use even when assessed with a non-production task: Evidence from left brain-damaged patients.

    PubMed

    Lesourd, Mathieu; Budriesi, Carla; Osiurak, François; Nichelli, Paolo F; Bartolo, Angela

    2017-12-20

    In the literature on apraxia of tool use, it is now accepted that using familiar tools requires semantic and mechanical knowledge. However, mechanical knowledge is nearly always assessed with production tasks, so one may assume that mechanical knowledge and familiar tool use are associated only because of their common motor mechanisms. This notion may be challenged by demonstrating that familiar tool use depends on an alternative tool selection task assessing mechanical knowledge, where alternative uses of tools are assumed according to their physical properties but where actual use of tools is not needed. We tested 21 left brain-damaged patients and 21 matched controls with familiar tool use tasks (pantomime and single tool use), semantic tasks and an alternative tool selection task. The alternative tool selection task accounted for a large amount of variance in the single tool use task and was the best predictor among all the semantic tasks. Concerning the pantomime of tool use task, group and individual results suggested that the integrity of the semantic system and preserved mechanical knowledge are neither necessary nor sufficient to produce pantomimes. These results corroborate the idea that mechanical knowledge is essential when we use tools, even when tasks assessing mechanical knowledge do not require the production of any motor action. Our results also confirm the value of pantomime of tool use, which can be considered as a complex activity involving several cognitive abilities (e.g., communicative skills) rather than the activation of gesture engrams. © 2017 The British Psychological Society.

  18. 40 CFR 145.13 - Requirements for enforcement authority.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... willfully violates any program requirement. Note: In many States the State Director will be represented in... degree of knowledge or intent required under State law for establishing violations under paragraph (a)(3) of this section, shall be no greater than the burden of proof or degree of knowledge or intent EPA...

  19. 48 CFR 306.303-1 - Requirements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Requirements. 306.303-1... ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 306.303-1 Requirements. (b... written in a manner to permit an individual without technical knowledge of the requirement to understand...

  20. 48 CFR 306.303-1 - Requirements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Requirements. 306.303-1... ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 306.303-1 Requirements. (b... written in a manner to permit an individual without technical knowledge of the requirement to understand...