Anthropology. Teacher Edition. Revised [and] Student Edition.

ERIC Educational Resources Information Center

Stark, Rebecca

The teacher and student editions of this book introduce students to the subject of anthropology and the subfields into which it is divided. Students learn about the beginnings of anthropology as an outgrowth of the curiosity stimulated by the Age of Exploration and how it grew into the basic field it is today. Students examine the origins and…

Biological Science: An Ecological Approach. BSCS Green Version. Teacher's Edition. Sixth Edition.

ERIC Educational Resources Information Center

Biological Sciences Curriculum Study, Colorado Springs.

This book is the teacher's edition to the 1987 edition of the Biological Sciences Curriculum Study Green Version textbook. It contains directions for teaching with this version, a description of the accompanying materials, teaching strategies by chapters, lists of useful software, safety guidelines, a materials list, chemical safety information,…

Diesel Technology: Safety Skills. Teacher Edition [and] Student Edition. Second Edition.

ERIC Educational Resources Information Center

Kellum, Mary

Teacher and student editions of this document are one in a series of competency-based instructional materials for diesel technology programs. The series aligns with the medium/heavy diesel duty truck task list used by the National Institute for Automotive Service Excellence in the certification of medium/heavy duty truck technicians. Introductory…

Civil Technology Applications. Teacher Edition [and] Student Edition.

ERIC Educational Resources Information Center

Schertz, Karen

Teacher and student editions of Civil Technology Applications are one in a series of competency-based instructional materials for drafting and civil technology programs. It includes the technical content and tasks necessary for a student to be employed as a drafter or civil technician in a civil engineering firm. Introductory pages in the teacher…

Diesel Technology: Workplace Skills. Teacher Edition and Student Edition.

ERIC Educational Resources Information Center

Kellum, Mary

This publication consists of instructional materials to provide secondary and postsecondary students with skills useful in pursuing a career in the diesel industry. Introductory materials in the teacher edition include information on use of the publication, competency profile, instructional/task analysis, related academic and workplace skills…

Basic Science Living Skills for Today's World. Teacher's Edition.

ERIC Educational Resources Information Center

Zellers (Robert W.) Educational Services, Johnstown, PA.

This document is a teacher's edition of a basic skills curriculum in science for adult basic education (ABE) students. The course consists of 25 lessons on basic science concepts, designed to give students a good understanding of the biological and physical sciences. Suggested activities and experiments that the student can do are also included.…

Basic Wiring. Fourth Edition. Teacher Edition [and] Student Guide [and] Student Workbook 1 [and] Student Workbook 2.

ERIC Educational Resources Information Center

Kaltwasser, Stan; Flowers, Gary; Blasingame, Don

Basic Wiring, first in a series of three wiring publications, serves as the foundation for students enrolled in a wiring program. It is a prerequisite to Commercial and Industrial Wiring or Residential Wiring. Instructional materials include a teacher edition, student guide, and two student workbooks. The teacher edition begins with introductory…

Health Activities Project (HAP), Trial Edition III.

ERIC Educational Resources Information Center

Buller, Dave; And Others

Contained within this Health Activities Project (HAP) trial edition (set III) are a teacher information folio and numerous student activity folios which center around the idea that students in grades 5-8 can control their own health and safety. Each student folio is organized into an Overview, Health Background, Materials, Setting Up, and…

Diesel Technology: Steering and Suspension. Second Edition. Teacher Edition [and] Student Edition.

ERIC Educational Resources Information Center

Miller, Roger; Scarberry, Terry; Tesch, Carl; Kellum, Mary

These teacher and student editions on steering and suspension are part of the diesel mechanics series of instructional materials. The series aligns with the medium/heavy duty truck task list developed by the National Automotive Technicians Education Foundation and used by the National Institute for Automotive Service Excellence in the…

Health Activities Project (HAP), Trial Edition II.

ERIC Educational Resources Information Center

Buller, Dave; And Others

Contained within this Health Activities Project (HAP) trial edition (set II) are a teacher information folio and numerous student activity folios which center around the idea that students in grades 5-8 can control their own health and safety. Each student folio is organized into a Synopsis, Health Background, Materials, Setting Up, and Activities…

Commercial and Industrial Wiring. Fourth Edition. Teacher Edition [and] Student Guide [and] Student Workbook 1 [and] Student Workbook 2.

ERIC Educational Resources Information Center

Kaltwasser, Stan; Flowers, Gary

Commercial and Industrial Wiring, third in a series of three wiring publications, includes the additional technical knowledge and applications required for job entry in the commercial and industrial wiring trade. Instructional materials include a teacher edition, student guide, and two student workbooks. The teacher edition begins with…

Power Product Equipment Technician: Equipment Systems. Teacher Edition. Student Edition.

ERIC Educational Resources Information Center

Hilley, Robert

This packet contains teacher and student editions on the topic of equipment systems, intended for the preparation of power product equipment technicians. This publication contains seven units: (1) principles of power transmission; (2) mechanical drive systems; (3) principles of fluid power; (4) hydraulic and pneumatic drive systems; (5) wheel and…

Fostering Teacher Candidates' Reflective Practice through Video Editing

ERIC Educational Resources Information Center

Trent, Margaret; Gurvitch, Rachel

2015-01-01

Recently, interest in using video to promote the reflective practice in preservice teacher education has increased. Video recordings of teaching incidents inspire the reflective practice in preservice teachers by allowing them to analyze instruction and view teaching in an objective light. As an extension of video recording, video editing has…

First Season Catfish Farming. A Workbook for Beginning Pond and Cage Culture of Channel Catfish. Teacher Edition and Student Edition.

ERIC Educational Resources Information Center

Oklahoma State Board of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This workbook, comprised of both the teacher and student editions, presents guidelines useful for first-year catfish farmers in Oklahoma using pond or cage cultures to raise channel catfish. The teacher edition is a set of unit guidelines only. Contents include a list of suggested readings, important addresses with types of information available…

Shielded Metal Arc Welding and Carbon Arc Cutting--Air. Teacher Edition [and] Student Edition [and] Student Workbook. Third Edition.

ERIC Educational Resources Information Center

Harper, Eddie; Knapp, John

This document contains the teacher and student texts and student workbook for a secondary-level course in shielded metal arc welding (SMAW) and carbon arc cutting that consists of units on the following topics: SMAW safety; SMAW equipment, applications, and techniques; hardfacing; and carbon arc cutting--air. The teacher edition includes the…

Greenhouse Management and Operations. Teacher Edition.

ERIC Educational Resources Information Center

Gowdy, Mary Ann Schwartz

This document is the teacher's edition of a module containing 16 instructional units covering competencies for students with career aspirations in horticulture. It is designed to provide high school students with an in-depth perspective of both the technical and the commercial aspects of running a greenhouse. The 16 units cover the following…

Teachers and the Law. Sixth Edition.

ERIC Educational Resources Information Center

Fischer, Louis; Schimmel, David; Stellman, Leslie

This book is about teachers and the laws that affect them. New to this sixth edition are new court cases and a chapter that highlights likely controversies in the coming years, including school choice, high-stakes testing, control of the Internet, and gang clothing. The book is divided into two parts. Part I, "The Legal Aspects of Teaching,"…

Well-Being, Teacher's Edition. Probing the Natural World/3.

ERIC Educational Resources Information Center

Florida State Univ., Tallahassee. Dept. of Science Education.

The teacher's edition for the Intermediate Science Curriculum Study Level III unit entitled "Well-Being" provides instructions for teachers. The main thrust of this unit is on examining some principles of human physiology and how these are affected by various substances. A brief introduction dealing with concepts of food, smoking,…

Comparative Critical Discourse Analysis of Student and Teacher Editions of Secondary Christian American Literature Textbooks

ERIC Educational Resources Information Center

Agiro, Christa Preston

2012-01-01

This article discusses the comparative application of critical discourse analysis to student and teacher editions of the two most widely used high school American literature textbooks by Christian publishers, examining them through the lens of critical theory. The study examined all parts of the student and teacher editions, excepting literary…

Probing the Natural World, Level III, Teacher's Edition: Environmental Science. Intermediate Science Curriculum Study.

ERIC Educational Resources Information Center

Bonar, John R., Ed.; Hathway, James A., Ed.

This is the teacher's edition of one of the eight units of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). This unit and its activities focuses on environmental pollution and hazards. Optional excursions are suggested for students who wish to study an area in greater depth. An introduction describes the problem…

Probing the Natural World, Level III, Teacher's Edition: Well-Being. Intermediate Science Curriculum Study.

ERIC Educational Resources Information Center

Bonar, John R., Ed.; Hathway, James A., Ed.

This is the teacher's edition of one of the eight units of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). This unit focuses on hazards to the body from drug use. Activities are given that relate to the topic. Optional excursions are suggested for students who wish to study an area in greater depth. An…

Psychology Teacher's Resource Book. First Course, Third Edition.

ERIC Educational Resources Information Center

Johnson, Margo, Ed.; Wertheimer, Michael, Ed.

Now in its third edition, this book contains background materials and resources for teaching introductory high school psychology. There are 11 chapters. Textbooks appropriate for introductory courses are reviewed in the first chapter. Books of reading which are a potentially valuable source of information to both student and teacher are listed in…

The Effective Teacher's Guide to Autism and Communication Difficulties: Practical Strategies, Second Edition. The Effective Teacher's Guides

ERIC Educational Resources Information Center

Farrell, Michael

2011-01-01

In this welcome second edition of "The Effective Teacher's Guide to Autism and Communication Difficulties", best-selling author Michael Farrell addresses how teachers and others can develop provision for students with autism and students that have difficulties with speech, grammar, meaning, use of language and comprehension. Updated and expanded,…

Physics Lab Experiments and Correlated Computer Aids. Teacher Edition.

ERIC Educational Resources Information Center

Gottlieb, Herbert H.

Forty-nine physics experiments are included in the teacher's edition of this laboratory manual. Suggestions are given in margins for preparing apparatus, organizing students, and anticipating difficulties likely to be encountered. Sample data, graphs, calculations, and sample answers to leading questions are also given for each experiment. It is…

Technical Analysis of the Disruptive Behavior Rating Scale--Second Edition--Teacher Version

ERIC Educational Resources Information Center

Erford, Bradley T.; Clark, Kelly

2011-01-01

The reliability and validity of scores on the Disruptive Behavior Rating Scale-second edition-teacher version (DBRS-II-T) was analyzed. The DBRS-II-T was designed to assess teacher observations of students referred for behavioral difficulties. The five-factor model fit the data poorly, but convergent and diagnostic validities were excellent.…

Aquaculture. Teacher Edition.

ERIC Educational Resources Information Center

Walker, Susan S.

This color-coded guide was developed to assist teachers in helping interested students plan, build, stock, and run aquaculture facilities of varied sizes. The guide contains 15 instructional units, each of which includes some or all of the following basic components: objective sheet, suggested activities for the teacher, instructor supplements,…

Anatomy and Physiology. Module Set II: Major Body Systems. Teacher Edition [and] Student Edition. Surgical Technology.

ERIC Educational Resources Information Center

Hilley, Robert

This document, which is the second part of a two-part set of modules on anatomy and physiology for future surgical technicians, contains the teacher and student editions of an introduction to anatomy and physiology that consists of modules on the following body systems: integumentary system; skeletal system; muscular system; nervous system;…

Primary Sources: America's Teachers on Teaching in an Era of Change. Third Edition

ERIC Educational Resources Information Center

Scholastic Inc. and the Bill & Melinda Gates Foundation, 2013

2013-01-01

This third edition of "Primary Sources" represents a joint project of Scholastic and the Bill & Melinda Gates Foundation. It reports the views of more than 20,000 public school teachers on important issues related to their profession. Fielded in July 2013, the survey asks teachers about their motivation, new learning standards,…

How Teachers Taught: Constancy and Change in American Classrooms, 1890-1990. Second Edition. Research on Teaching Series.

ERIC Educational Resources Information Center

Cuban, Larry

This second edition updates material in the first edition for another decade to 1990 and responds to criticisms of findings in the first edition. This book investigates teaching practices before, during, and after 20th-century reform efforts aimed at changing what teachers routinely do. Patterns of stability and change over a 100-year period are…

Solving Discipline and Classroom Management Problems: Methods and Models for Today's Teachers. 6th Edition

ERIC Educational Resources Information Center

Wolfgang, Charles H.

2004-01-01

Offering a wide range of methods and practical advice, this sixth edition equips teachers with tools they need to deal effectively with a range of discipline/management problems in the classroom--from minor misbehavior to serious assaults. The following features are included in this edition: (1) A new chapter discusses how to deal with and support…

Anatomy and Physiology. Module Set I: Introduction to Anatomy and Physiology. Teacher Edition [and] Student Edition. Surgical Technology.

ERIC Educational Resources Information Center

Hilley, Robert

This document, which is the first part in a two-part set of modules on anatomy and physiology for future surgical technicians, contains the teacher and student editions of an introduction to anatomy and physiology that consists of modules on the following topics: (1) organization of the human body; (2) biochemistry and microbiology; (3) infection,…

Beyond the Margins: Evaluating the Support for Multicultural Education within Teachers' Editions of U.S. History Textbooks

ERIC Educational Resources Information Center

Stanton, Christine Rogers

2015-01-01

Although previous research has described analysis of history textbooks in terms of multicultural education, limited attention has been given to teacher only resources, such as the "wraparound features" of teachers' editions. The study highlighted in this article applies critical discourse analysis to explore the potential for teachers'…

Why You're You, Teacher's Edition. Probing the Natural World/3.

ERIC Educational Resources Information Center

Florida State Univ., Tallahassee. Dept. of Science Education.

The teacher's edition for the Intermediate Science Curriculum Study Level III unit entitled "Why You're You" provides specific suggestions for teaching the seven chapters included in the unit. The unit deals primarily with the concepts of genetics and a brief discussion is included in the beginning about some of the basic ideas in this…

The World of Business. Teacher's Activity and Resource Guide.

ERIC Educational Resources Information Center

Columbus Public Schools, OH.

This activity and resource guide is intended to assist teachers in developing course content and effective teaching methods in business education. (General Business for Economic Understanding," 11th edition, is the adopted textbook for this guide.) The guide is organized into twelve major units and is designed so that each unit builds upon the…

Surgical Techniques. Second Edition. Teacher Edition.

ERIC Educational Resources Information Center

Bushey, Vicki; And Others

This instructor's manual contains 18 units of instruction for a course on surgical technology designed to include the entry-level competencies students need as a surgical technologist. Each unit includes some or all of the following basic components of a unit of instruction: objective sheet, suggested activities for the teacher, assignment sheets…

What Great Teachers Do Differently: Seventeen Things That Matter Most. Second Edition

ERIC Educational Resources Information Center

Whitaker, Todd

2012-01-01

In the second edition of this renowned book, you will find pearls of wisdom, heartfelt advice, and inspiration from one of the nation's leading authorities on staff motivation, teacher leadership, and principal effectiveness. With wit and understanding, Todd Whitaker describes the beliefs, behaviors, attitudes, and interactions of great teachers…

Our Economy: How It Works. Activities and Investigation. Teacher's Edition.

ERIC Educational Resources Information Center

Clawson, Elmer U.

To help junior and senior high school students develop a better understanding of the United States' economy, this teacher's guide presents a series of learning activities centered around eight general themes. The topics (corresponding to the document's eight chapters) include both international and global economic issues as well as current…

Medical and Psychosocial Problems in the Classroom: The Teacher's Role in Diagnosis and Management. Fifth Edition

ERIC Educational Resources Information Center

Haslam, Robert H. A., Ed.; Valletutti, Peter J., Ed.

2016-01-01

Now in its fifth edition, this outstanding resource for teachers and school professionals has been retitled "Medical and Psychosocial Problems in the Classroom" to more accurately reflect what teachers encounter during the course of their careers. Each chapter highlights the important role teachers play when interacting with health-care…

101 "Answers" for New Teachers and Their Mentors: Effective Teaching Tips for Daily Classroom Use. Second Edition

ERIC Educational Resources Information Center

Breaux, Annette L.

2011-01-01

The 2nd edition of this bestselling title features brand new strategies plus illustrations! Make sure your new teachers are ready for the realities of the classroom. Be confident that their mentors are focused and effective. Organized so new teachers can read it by themselves, this book can also be studied collaboratively with veteran teachers who…

Power Product Equipment Technician: Lawn and Garden Equipment. Teacher Edition. Student Version.

ERIC Educational Resources Information Center

Hilley, Robert

This packet contains teacher and student editions for lawn and garden equipment repair and maintenance, intended for the preparation of power product equipment technicians. This publication contains four units: (1) introduction to lawn and garden equipment; (2) light-duty lawn and garden equipment; (3) heavy-duty lawn and garden equipment; and (4)…

Archaeology. Second Teacher Edition. Grades 5-12.

ERIC Educational Resources Information Center

Stark, Rebecca

This book includes a student edition by the same name and introduces students to various civilizations and their achievements. The self-directed activities emphasize higher-level thinking skills and activities keyed to "Bloom's Taxonomy." The table of contents lists: (1) "What Is Archaeology?"; (2) "What Is Culture?"; (3) "Where to Dig"; (4)…

Reading Assessment: A Primer for Teachers and Coaches. Second Edition. Solving Problems in the Teaching of Literacy

ERIC Educational Resources Information Center

Caldwell, JoAnne Schudt

2007-01-01

Now in a revised and expanded second edition, this invaluable book provides teachers and coaches with the information and tools they need to get started on the complex process of reading assessment. Grounded in a solid scientific framework, the book presents practical strategies that enable teachers to recognize "good reader" behaviors, assess…

Taking the Lead: New Roles for Teachers and School-Based Coaches, 2nd Edition

ERIC Educational Resources Information Center

Killion, Joellen; Harrison, Cindy

2017-01-01

"Taking the Lead" outlines 10 practical and powerful roles for school-based coaches responsible for helping teachers increase their capacity to serve all students. The second edition is a rich update to Killion and Harrison's essential resource and includes dozens of online tools that support deep exploration and implementation of the…

The Chicago Handbook for Teachers: A Practical Guide to the College Classroom. Second Edition

ERIC Educational Resources Information Center

Brinkley, Alan; El-Fakahany, Esam; Dessants, Betty; Flamm, Michael; Forcey, Charles B., Jr.; Ouellett, Mathew L.; Rothschild, Eric

2011-01-01

Those who teach college students have extensive training in their disciplines, but unlike their counterparts at the high school or elementary school level, they often have surprisingly little instruction in the craft of teaching itself. "The Chicago Handbook for Teachers, Second Edition", is an extraordinarily helpful guide for anyone facing the…

Editing in Technical Communication: Theory and Practice in Editing Processes at the Graduate Level.

ERIC Educational Resources Information Center

Masse, Roger E.

At New Mexico State University, technical communication teachers have developed a course to teach editing processes to graduate students who take the advanced workshop in technical and professional communication. In this seminar group, students work on writing processes; editing processes; written, edited, and tested products; and oral processes…

Urban Teaching: The Essentials. Third Edition

ERIC Educational Resources Information Center

Weiner, Lois; Jerome, Daniel

2016-01-01

This significantly revised edition will help prospective and new city teachers navigate the realities of city teaching. Now the classic introduction to urban teaching, this book explains how global, national, state, and local reforms have impacted what teachers need to know to not only survive, but to do their jobs well. The Third Edition melds…

Probing the Natural World, Level III, Teacher's Edition: Investigating Variation. Intermediate Science Curriculum Study.

ERIC Educational Resources Information Center

Bonar, John R., Ed.; Hathway, James A., Ed.

This is the teacher's edition of one of the eight units of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). This unit focuses on diversity in human populations, measurement, and data collection. Optional excursions are described for students who wish to study a topic in greater depth. An introduction describes…

Noise Pollution, Teachers' Edition.

ERIC Educational Resources Information Center

O'Donnell, Patrick A.; Lavaroni, Charles W.

One of three in a series about pollution, this teacher's guide for a unit on noise pollution is designed for use in junior high school grades. It offers suggestions for extending the information and activities contained in the textual material for students. Chapter 1 discusses the problem of noise pollution and involves students in processes of…

Water Pollution, Teachers' Edition.

ERIC Educational Resources Information Center

Lavaroni, Charles W.; And Others

One of three in a series about pollution, this teacher's guide for a unit on water pollution is designed for use in junior high school grades. It offers suggestions for extending the information and activities contained in the textual material for students. Chapter 1 discusses the problem of water pollution and involves students in processes of…

Creative Sciencing. Ideas and Activities for Teachers and Children. Grades K-6. Third Edition.

ERIC Educational Resources Information Center

De Vito, Alfred; Krockover, Gerald H.

This resource book includes 163 science activities for both preservice and in-service teachers. Activities have been field-tested and are cross-referenced according to the processes of science and the content area covered. Each activity has been written to evoke ideas from the reader, thus enabling each activity to serve a base for additional…

Kids Food CyberClub. Teacher's Guide. First Edition.

ERIC Educational Resources Information Center

Belyea, Monica

This guide is designed to help teachers educate students to be healthier now and in the future. It presents fun, learner-centered activities about nutrition, food, hunger, and food sources. It offers an overview of each section of the Kids Food CyberClub web site, and classroom activities teachers can use to expand on information students will…

Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation

PubMed Central

Tang, Weixin; Hu, Johnny H.; Liu, David R.

2017-01-01

Programmable sequence-specific genome editing agents such as CRISPR-Cas9 have greatly advanced our ability to manipulate the human genome. Although canonical forms of genome-editing agents and programmable transcriptional regulators are constitutively active, precise temporal and spatial control over genome editing and transcriptional regulation activities would enable the more selective and potentially safer use of these powerful technologies. Here, by incorporating ligand-responsive self-cleaving catalytic RNAs (aptazymes) into guide RNAs, we developed a set of aptazyme-embedded guide RNAs that enable small molecule-controlled nuclease-mediated genome editing and small molecule-controlled base editing, as well as small molecule-dependent transcriptional activation in mammalian cells. PMID:28656978

Medical-Surgical II. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This publication is designed to provide students with the knowledge they need to pursue a career in medical-surgical nursing. Fifteen units are provided. Each instructional unit includes some or all of the basic components of a unit of instruction: performance objectives, suggested activities for the teacher, information sheets, job sheets,…

Medical-Surgical I. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This publication is designed to provide students with the knowledge they need to pursue a career in medical-surgical nursing. Eight units are provided. Each instructional unit includes some or all of the basic components of a unit of instruction: performance objectives, suggested activities for the teacher, information sheets, job sheets, written…

Demography and You: Teacher Edition.

ERIC Educational Resources Information Center

McCrea, Lester C.; And Others

This teacher's guide is the grades 7-9 unit for population education developed for the Baltimore public schools. This mini-demography course covers various factors of population growth and change. The activities of the unit focus on seven major concepts: (1) demography provides information for understanding population growth, trends, and changes;…

"GFL2"! The Updated "Geography for Life: National Geography Standards, Second Edition"

ERIC Educational Resources Information Center

Heffron, Susan Gallagher

2012-01-01

"Geography for Life: National Geography Standards, Second Edition" ("GFL2") is the recently released update of the original edition published in 1994. The original edition of "Geography for Life" provided excellent guidance on geographic content for teachers, curriculum designers, publishers, and pre-service teachers as well as many other…

How to Get the Teaching Job You Want: The Complete Guide for College Graduates, Teachers Changing Schools, Returning Teachers and Career Changers. Second Edition

ERIC Educational Resources Information Center

Feirsen, Robert; Weitzman, Seth

2004-01-01

Competition for the best teaching jobs is becoming more intense. Since publication of the first edition, when it was mainly the most desirable schools that were deluged by applications, the economic climate has made the teacher market more competitive across the board, and is changing hiring practices. Now extensively revised, this book maintains…

An Economic Course for Elementary School Teachers. Second Revised Edition.

ERIC Educational Resources Information Center

Lovell, Hugh; Harter, Charlotte

This handbook is intended to help economic educators develop teacher training courses for demonstrating to classroom teachers how to teach economics to children, grades 1-9. Teachers enrolled in the course carry out their own pupil activities which teach economic ideas. These activities include problem solving, case studies, skits, making posters,…

The Handbook of Literacy Assessment and Evaluation. Second Edition.

ERIC Educational Resources Information Center

Harp, Bill

This handbook gives teachers, reading specialists, administrators, or students concise, up-to-date information on the most popular assessment and evaluation tools in literacy. This second edition retains many of the tools reviewed in the first edition and adds 12 new tools. The first section reviews 24 tools that are teacher-made. The second…

Safety in Science for Primary Schools. 1st Edition.

ERIC Educational Resources Information Center

Association for Science Education, Cambridge (England).

This packet of teacher education materials is based on the publication "Be Safe!" and is intended for those teaching science to children ages 4 to 12. The pack contains INSET materials that supplement a safety exhibition contained in the second edition of "Be Safe!." Five basic activities include instructions for training…

Requirements for Certification for Elementary Schools, Secondary Schools, Junior Colleges: Teachers, Counselors, Librarians, Administrators. Forty-Ninth Edition, 1984-85.

ERIC Educational Resources Information Center

Burks, Mary P.

This edition of "Requirements for Certification" updates pertinent information on certification requirements for teachers, administrators, librarians, counselors, and other school personnel in each state in the United States. Outlines are provided of recommendations on certification by the following regional and national associations: Middle…

Basic Facialist. Teacher Edition. Cosmetology Series.

ERIC Educational Resources Information Center

Rogers, Jeanette A.

This Oklahoma curriculum guide contains six units. Each instructional unit includes some or all of these basic components: performance objectives; suggested activities for the teacher; pretest; handouts; information sheets; transparency masters; assignment sheets; job sheets; practical tests; written tests; and answers to pretest, assignment…

Aquaculture. Second Edition. Teacher Edition.

ERIC Educational Resources Information Center

Walker, Susan S.; Crummett, Dan

This teacher and student guide for aquaculture contains 15 units of instruction that cover the following topics: (1) introduction to aquaculture; (2) the aquatic environment; (3) fundamental fish biology; (4) marketing; (5) site selection; (6) facility design and layout; (7) water quality management; (8) fish health management; (9) commercial…

Exploring Technology Education. Second Edition. Teacher Guide.

ERIC Educational Resources Information Center

Murray, Steve

This color-coded guide was developed to help teachers provide middle school and junior high students with an activity-oriented approach to learning and thinking about technology. Through the instruction and the activities, students are shown how the different systems interrelate, how they influence everyday life, and how they combine in a…

A Vector Approach to Euclidean Geometry: Inner Product Spaces, Euclidean Geometry and Trigonometry, Volume 2. Teacher's Edition.

ERIC Educational Resources Information Center

Vaughan, Herbert E.; Szabo, Steven

This is the teacher's edition of a text for the second year of a two-year high school geometry course. The course bases plane and solid geometry and trigonometry on the fact that the translations of a Euclidean space constitute a vector space which has an inner product. Congruence is a geometric topic reserved for Volume 2. Volume 2 opens with an…

Mechanical Drafting with CAD. Teacher Edition.

ERIC Educational Resources Information Center

McClain, Gerald R.

This instructor's manual contains 13 units of instruction for a course on mechanical drafting with options for using computer-aided drafting (CAD). Each unit includes some or all of the following basic components of a unit of instruction: objective sheet, suggested activities for the teacher, assignment sheets and answers to assignment sheets,…

Human Resources Administration: A School-Based Perspective. Fourth Edition

ERIC Educational Resources Information Center

Smith, Richard

2009-01-01

Enhanced and updated, this Fourth Edition of Richard E. Smith's highly successful text examines the growing role of the principal in planning, hiring, staff development, supervision, and other human resource functions. The Fourth Edition includes new sections on ethics, induction, and the role of the mentor teacher. This edition also introduces…

Shielded Metal Arc Pipe Welding. Teacher Edition. Second Edition.

ERIC Educational Resources Information Center

Fortney, Clarence; And Others

This second edition of the shielded metal arc pipe welding curriculum guide presents both basic and advanced pipe welding skills. All specifications for procedure and welder qualification are presented according to national standards. The standards also include the test position for both groove and fillet pipe welding. The guide contains three…

Making the Journey: Being and Becoming a Teacher of English Language Arts. Second Edition.

ERIC Educational Resources Information Center

Christenbury, Leila

This book takes a look at the realities of classroom life, offering specific suggestions for dealing effectively with today's students. More than a compendium of activities, the first edition of the book introduced educators to a philosophy of teaching illustrated and implemented by workable, realistic techniques. The second edition of the book…

Requirements for Certification [of] Teachers, Counselors, Librarians, Administrators for Elementary Schools, Secondary Schools, Junior Colleges. Forty-eighth Edition, 1983-84.

ERIC Educational Resources Information Center

Woellner, Elizabeth H.

This edition of "Requirements for Certification" updates pertinent information on certification requirements for teachers, administrators, librarians, counselors, and other school personnel in each state in the United States. Outlines are provided of recommendations on certification by regional and national associations, and sources of information…

The Story of California. Student Workbook. Teacher's Edition = Libro de Trabajo de La Historia de California. Edicion del Maestro.

ERIC Educational Resources Information Center

Gray (Naomi) Associates, Inc., San Francisco, CA.

The workbook is designed to accompany a textbook, "The Story of California," a Spanish-English bilingual history and geography of the state intended for classroom use by limited-English-proficient, native Spanish-speaking students in California's urban middle schools. The teacher's edition, presented here, consists of reproductions of 51…

Hands-On Environmental Science Activities. Teacher's Edition. First Edition.

ERIC Educational Resources Information Center

Kutscher, Eugene

The ability of students to go beyond facts and to think critically, while at the same time enjoying and valuing the learning process, is fundamental to science and environmentalism. This book provides enrichment activities for the science curriculum that provide concrete connections with important world events. Each activity is self-contained and…

ACR Electrical Systems. Teacher Edition [and] Student Edition.

ERIC Educational Resources Information Center

Clemons, Mark

This document contains a teacher's guide and student guide for a high school-level competency-based course in air conditioning and refrigeration (ACR) equipment electrical systems. Presented in the teacher's guide are the following: explanation of the instructional units' use; competency profile for recording students' performance of the tasks in…

The Inside Story [Learning Packages for Exploratory Career Education--7th and 8th Grades: Teacher and Student Editions.

ERIC Educational Resources Information Center

Kemp, Louie E., Comp.

The four learning packages for exploratory career education are designed for use at the seventh and eighth grade levels. Each unit includes coordinated teacher and student editions. The units are: Culinary Cubs, focusing on occupations in the areas of food management, production, and services, with special reference to dietitians; Mini Nursery,…

Basics of Desktop Publishing. Second Edition.

ERIC Educational Resources Information Center

Beeby, Ellen; Crummett, Jerrie

This document contains teacher and student materials for a basic course in desktop publishing. Six units of instruction cover the following: (1) introduction to desktop publishing; (2) desktop publishing systems; (3) software; (4) type selection; (5) document design; and (6) layout. The teacher edition contains some or all of the following…

Audiovisual Materials for Teaching Economics. Third Edition.

ERIC Educational Resources Information Center

Harter, Charlotte T.; And Others

The third edition of this catalog, which expands and revises earlier editions, annotates audiovisual items for economic education in kindergarten through college. The purpose of the catalog is to help teachers select sound economic materials for classroom use. A selective listing, the catalog cites over 700 items out of more than 1200 items…

Mentoring New Teachers. Updated Edition.

ERIC Educational Resources Information Center

Portner, Hal

This book includes step-by-step instructions to help experienced teachers become just as skilled at mentoring beginning teachers as they are at teaching. It describes how teacher mentors can: relate to their proteges in ways that establish good working rapport; assess how the mentoring is progressing and make necessary adjustments; coach proteges…

No evidence of genome editing activity from Natronobacterium gregoryi Argonaute (NgAgo) in human cells.

PubMed

Javidi-Parsijani, Parisa; Niu, Guoguang; Davis, Meghan; Lu, Pin; Atala, Anthony; Lu, Baisong

2017-01-01

The argonaute protein from the thermophilic bacterium Thermus thermophilus shows DNA-guided DNA interfering activity at high temperatures, complicating its application in mammalian cells. A recent work reported that the argonaute protein from Natronobacterium gregoryi (NgAgo) had DNA-guided genome editing activity in mammalian cells. We compared the genome editing activities of NgAgo and Staphylococcus aureus Cas9 (SaCas9) in human HEK293T cells side by side. EGFP reporter assays and DNA sequencing consistently revealed high genome editing activity from SaCas9. However, these assays did not demonstrate genome editing activity by NgAgo. We confirmed that the conditions allowed simultaneous transfection of the NgAgo expressing plasmid DNA and DNA guides, as well as heterologous expression of NgAgo in the HEK293T cells. Our data show that NgAgo is not a robust genome editing tool, although it may have such activity under other conditions.

Surgical Procedures. Second Edition. Teacher Edition.

ERIC Educational Resources Information Center

Baker, Beverly; And Others

This teacher's guide contains 13 units of instruction for a course that will prepare students with the entry-level competencies needed by a surgical technologist. The course covers the following topics: introduction to surgical procedures; diagnostic procedures; general surgery; gastrointestinal surgery; obstetrics and gynecological surgery;…

Teaching Responsibility through Physical Activity. Second Edition.

ERIC Educational Resources Information Center

Hellison, Don

This book guides teachers in using physical activity to foster personal and social responsibility. Focusing on teaching in school settings, the book features comments from real students to motivate teachers to apply the concept; take-aways that summarize each chapter and help teachers consider their own situations; new chapters on the lesson plan…

Teacher Quality Toolkit. 2nd Edition

ERIC Educational Resources Information Center

Lauer, Patricia A.; Dean, Ceri B.; Martin-Glenn, Mya L.; Asensio, Margaret L.

2005-01-01

The Teacher Quality Toolkit addresses the continuum of teacher learning by providing tools that can be used to improve both preservice, and inservice teacher education. Each chapter provides self assessment tools that can guide progress toward improved teacher quality and describes resources for designing exemplary programs and practices. Chapters…

Teacher Activity Survey.

ERIC Educational Resources Information Center

Delaware Univ., Newark. School of Education.

The purpose of this survey is to determine what teachers think are (a) the relevant teaching activities, skills, or procedures and (b) the appropriate time and place to develop competence in an activity. Multiple choice responses are given for each of the following teacher activities: (a) utilize more than one approach to controlling and…

The Lecturer's Toolkit: A Resource for Developing Learning, Teaching & Assessment. Second Edition.

ERIC Educational Resources Information Center

Race, Phil

This "toolkit" ring binder is designed to help teachers develop their professional practice in higher education and to enhance their instruction and assessment. A smaller bound version of this second edition is designed to be used by individual lecturers as their personal copy; it contains fewer tasks and activities. The chapters are: (1)…

An analysis of teacher’s preparation in implementing 2013 revision edition curriculum on mathematics specialization learning

NASA Astrophysics Data System (ADS)

Susilo, T.; Suryawan, A.

2018-05-01

This study aimed to determine the pedagogical competence of teachers, the readiness of planning and implementation of learning related to the implementation 2013 revised edition curriculum on mathematics specialization learning for senior high schools Wonogiri. Informants in this study there are 6 high school mathematics teachers X and XI class who teach in the school district Wonogiri. Data were collected using questionnaire method, interview, observation and documentation. Qualitative data analysis is done interactively through 4 paths: data collection, data reduction, data display, drawing conclusion. The results showed that high school mathematics teacher class X and XI in school district of Wonogiri City. The results show that most high school mathematics teachers in grade X and XI are ready to implement the 2013 revised edition curriculum and a few have not been able to implement due to internal or external factors. High school math teachers at Wonogiri district who are ready to face the 2013 revised edition curriculum have applied 10 teacher pedagogic competency indicators according to Regulation of the national education ministry Number 16 Year 2007 in learning. The readiness and implementation of mathematics learning is in line with the demands of the 2013 revised edition curriculum. Based on the teachers who are not ready, data on issues that arise in the implementation of the 2013 revised edition curriculum. Especially the problems in learning, namely mismatch of Core Competence (KI) and Basic Competence (KD) in teacher manual, material disregard in student handbook and lack of examples of problems that exist in teacher manual.

"Convenience Editors" as Legitimate Participants in the Practice of Scientific Editing: An Interview Study

ERIC Educational Resources Information Center

Willey, Ian; Tanimoto, Kimie

2013-01-01

Native-English-speaking English teachers at universities in EFL contexts are often asked to edit scientific manuscripts written by English as an additional language (EAL) colleagues. However, a lack of familiarity with scientific writing can make such editing tasks burdensome to English teachers. Using Lave and Wenger's (1991) notion of legitimate…

Residential Wiring. Teacher Edition [and] Student Edition. Third Edition.

ERIC Educational Resources Information Center

Taylor, Mark; Batson, Larry; Carroll, Charles; Ipock, Dan; Leak, Lester; Onstott, Todd

This revised curriculum guide for teachers and students is designed to help prepare students for entry-level employment in the residential wiring trade. The curriculum guide contains six units that cover the following topics: (1) blueprint reading and load calculations; (2) service; (3) rough-in; (4) trim out and troubleshooting; (5) low voltage…

Measurement and Assessment in Teaching. Eighth Edition.

ERIC Educational Resources Information Center

Linn, Robert L.; Gronlund, Norman E.

This book is intended to introduce the classroom teacher and prospective teacher to the elements of measurement and assessment that are essential to good teaching. The main theme is that assessment plays an important role in the instructional process. This edition has been revised to reflect major changes in educational assessment since the last…

New Teachers Handbook. Second Edition.

ERIC Educational Resources Information Center

IMPACT II--The Teachers Network, New York, NY.

This practical guide for new teachers is written by teachers and offers strategies for the early years of teaching that cover classroom practice and professional development. Seven chapters address teaching practice and cover the following topics: getting to know students at the beginning of the year; strategic planning for the whole year;…

Teaching Outside the Box: How to Grab Your Students by Their Brains, 2nd Edition

ERIC Educational Resources Information Center

Johnson, LouAnne

2011-01-01

This second edition of the bestselling book includes practical suggestions for arranging your classroom, talking to students, avoiding the misbehavior cycle, and making your school a place where students learn and teachers teach. The book also contains enlivening Q&A from teachers, letters from students, and tips for grading. This new edition has…

The Minority Experience: A Basic Bibliography of American Ethnic Studies. Revised and Enlarged Edition.

ERIC Educational Resources Information Center

Caselli, Ron, Comp.

Approximately 1500 books published between 1940 and 1974 constitute this revised edition of the 1970 minority experience bibliography. It is said to be directed at teachers in inservice activities and students of American minority groups. Afro-Americans and native Americans are covered with additional sections on the Asian-American, Euro-American,…

Matematicas en la vida actual. Volumen II, edicion para el maestro. (Mathematics: A Practical View. Volume II, Teacher Edition). Applied Basic Curriculum Series.

ERIC Educational Resources Information Center

Evaluation, Dissemination and Assessment Center, Dallas.

This Spanish language teacher's edition of a practical mathematics text for the intermediate grades contains three components which can be structured in different combinations according to different student needs. Built around a review of selected objectives in the mathematics basic curriculum, the material is intended to stimulate interest in…

Matematicas en la vida actual. Volumen I, edicion para el maestro. (Mathematics: A Practical View. Volume I, Teacher Edition). Applied Basic Curriculum Series.

ERIC Educational Resources Information Center

Evaluation, Dissemination and Assessment Center, Dallas.

This Spanish language teacher's edition of a practical mathematics text for the intermediate grades contains three components which can be structured in different combinations according to different student needs. Built around a review of selected objectives in the mathematics basic curriculum, the material is intended to stimulate interest in…

Matematicas en la vida actual. Volumen III, edicion para el maestro. (Mathematics: A Practical View. Volume III, Teacher Edition). Applied Basic Curriculum Series.

ERIC Educational Resources Information Center

Evaluation, Dissemination and Assessment Center, Dallas.

This Spanish language teacher's edition of a practical mathematics text for the intermediate grades contains three components which can be structured in different combinations according to different student needs. Built around a review of selected objectives in the mathematics basic curriculum, the material is intended to stimulate interest in…

How Teachers Are Changing Schools. First Edition.

ERIC Educational Resources Information Center

IMPACT II--The Teachers Network, New York, NY.

The Teachers Network created The Teachers Voice Initiative to bring teachers together and empower them to create their vision of the future of education. This book presents the perspectives of participating teachers, who report on their experiences as agents of change and designers of curriculum. Papers include: "Teacher Leadership for Creating…

Inventory America: Residential Buildings. Student Workbook, Pilot Edition; Teacher & Project Supervisor Manual, Pilot Edition.

ERIC Educational Resources Information Center

Haupt, Richard; Pomeroy, Robert W., Ed.

Designed as a special studies unit for secondary school students or for adult volunteers, this student workbook and teacher's guide explains how to produce an accurate record of memorable neighborhood houses. The activities in the workbook include observation and information gathering. The workbook sections describe various steps in the process…

Biology Research Activities: Teacher's Edition (with Answers).

ERIC Educational Resources Information Center

Newman, Barbara

This book is part of the series "Explorations in Science" which contains enrichment activities for the general science curriculum. Each book in the series contains innovative and traditional projects for both the bright and average, the self-motivated, and those who find activity motivating. Each activity is self-contained and provides everything…

Employment in Agribusiness. Teacher Edition. Second Edition.

ERIC Educational Resources Information Center

Crummett, Dan M.; Newport, Alan K.

This curriculum guide is designed to help teachers prepare students with the variety of skills that will help them obtain jobs that can turn into rewarding careers in agribusiness. The guide also serves as a resource for students participating in agricultural sales and service competitions sponsored by student organizations such as Future Farmers…

Environmental Involvement. . . A Teacher's Guide (2nd Edition).

ERIC Educational Resources Information Center

1971

Presented in this teacher's guide are ideas and projects to help students develop an awareness and appreciation of their environment. Sharpening the senses is emphasized through activities dealing with water quality, sound qualities, and noise, air quality, solid waste control, and soil management. The text is divided into four levels roughly…

On Being a "Scholarly" Teacher

ERIC Educational Resources Information Center

Prenkert, Jamie Darin

2013-01-01

In this article, the author shares his thoughts on being a "scholarly" teacher. He points out that engaging in scholarly activity, which includes publishing as well as other ways to engage with relevant research, like reviewing and editing for journals, can lead to better teaching. This sort of scholarly commitment allows an instructor to maintain…

Peer-Editing Practice in the Writing Classroom: Benefits and Drawbacks

ERIC Educational Resources Information Center

Deni, Ann Rosnida Md.; Zainal, Zainor Izat

2011-01-01

Small scale studies have shown that peer-editing is beneficial to students as it increases their awareness of the complex process of writing, it improves their knowledge of and skills in writing and helps them become more autonomous in learning. Teachers too may benefit from peer-editing as this practice discloses invaluable information on…

Modern Indian Psychology. Revised Edition.

ERIC Educational Resources Information Center

Bryde, John F.

Written on the basis of senior Indian verbal relatings collected over a 23-year span, this revised edition on modern Indian psychology incorporates suggestions from Indian students and their teachers, Indian and non-Indian social studies experts, and other Indian people. The book contains 6 major divisions: (1) "Culture and Indian…

The International News Journal, Inc. Teacher Resource Manual [and] Student Activities. Second Edition. Exploring the Marketplace Series.

ERIC Educational Resources Information Center

Reinke, Robert; McGuire, Margit; Reinke, Diane Wilcox

This teacher resource manual and student activities economics education unit provides students with the opportunity to use economic content and related skills as they learn about the U.S. economic system and its relationship to the world economy. The lessons link to economic content and other subject areas traditionally taught in grades 5, 6, and…

Regulation of Gene Editing Activity Directed by Single-Stranded Oligonucleotides and CRISPR/Cas9 Systems

PubMed Central

Bialk, Pawel; Rivera-Torres, Natalia; Strouse, Bryan; Kmiec, Eric B.

2015-01-01

Single-stranded DNA oligonucleotides (ssODNs) can direct the repair of a single base mutation in human genes. While the regulation of this gene editing reaction has been partially elucidated, the low frequency with which repair occurs has hampered development toward clinical application. In this work a CRISPR/Cas9 complex is employed to induce double strand DNA breakage at specific sites surrounding the nucleotide designated for exchange. The result is a significant elevation in ssODN-directed gene repair, validated by a phenotypic readout. By analysing reaction parameters, we have uncovered restrictions on gene editing activity involving CRISPR/Cas9 complexes. First, ssODNs that hybridize to the non-transcribed strand direct a higher level of gene repair than those that hybridize to the transcribed strand. Second, cleavage must be proximal to the targeted mutant base to enable higher levels of gene editing. Third, DNA cleavage enables a higher level of gene editing activity as compared to single-stranded DNA nicks, created by modified Cas9 (Nickases). Fourth, we calculated the hybridization potential and free energy levels of ssODNs that are complementary to the guide RNA sequences of CRISPRs used in this study. We find a correlation between free energy potential and the capacity of single-stranded oligonucleotides to inhibit specific DNA cleavage activity, thereby indirectly reducing gene editing activity. Our data provide novel information that might be taken into consideration in the design and usage of CRISPR/Cas9 systems with ssODNs for gene editing. PMID:26053390

Regulation of Gene Editing Activity Directed by Single-Stranded Oligonucleotides and CRISPR/Cas9 Systems.

PubMed

Bialk, Pawel; Rivera-Torres, Natalia; Strouse, Bryan; Kmiec, Eric B

2015-01-01

Single-stranded DNA oligonucleotides (ssODNs) can direct the repair of a single base mutation in human genes. While the regulation of this gene editing reaction has been partially elucidated, the low frequency with which repair occurs has hampered development toward clinical application. In this work a CRISPR/Cas9 complex is employed to induce double strand DNA breakage at specific sites surrounding the nucleotide designated for exchange. The result is a significant elevation in ssODN-directed gene repair, validated by a phenotypic readout. By analysing reaction parameters, we have uncovered restrictions on gene editing activity involving CRISPR/Cas9 complexes. First, ssODNs that hybridize to the non-transcribed strand direct a higher level of gene repair than those that hybridize to the transcribed strand. Second, cleavage must be proximal to the targeted mutant base to enable higher levels of gene editing. Third, DNA cleavage enables a higher level of gene editing activity as compared to single-stranded DNA nicks, created by modified Cas9 (Nickases). Fourth, we calculated the hybridization potential and free energy levels of ssODNs that are complementary to the guide RNA sequences of CRISPRs used in this study. We find a correlation between free energy potential and the capacity of single-stranded oligonucleotides to inhibit specific DNA cleavage activity, thereby indirectly reducing gene editing activity. Our data provide novel information that might be taken into consideration in the design and usage of CRISPR/Cas9 systems with ssODNs for gene editing.

Instructional Supervision: Applying Tools and Concepts. 2nd Edition

ERIC Educational Resources Information Center

Zepeda, Sally J.

2007-01-01

The first edition of this book was highly regarded by both professors and students for its practicality and its: (1) coverage of tools & strategies to help supervisors work effectively with teachers; (2) up-to-date approach to clinical supervision which includes teacher portfolios, action research, peer coaching, and other innovative practices;…

The Role of Unions in the American Economy. Second Edition.

ERIC Educational Resources Information Center

Marshall, Ray; Rungeling, Brian

Intended as a resource for secondary teachers, this book analyzes the role of unions in the American economy and examines the main forces influencing unions in the United States. This second edition includes important domestic and external events that have affected U.S. economic policy and unions since the first edition was published in 1976.…

The Principal as Instructional Leader: A Practical Handbook. 3rd Edition

ERIC Educational Resources Information Center

Zepeda, Sally J.

2013-01-01

In the updated third edition of this highly successful book, leadership expert, Sally Zepeda offers savvy advice to both new and seasoned principals and assistant principals. You get practical tools and strategies, along with real-world examples to help you improve teacher effectiveness and boost student achievement. This edition features valuable…

Me and My Environment, Unit V: Air and Water in My Environment, Experimental Edition 1973-74.

ERIC Educational Resources Information Center

Biological Sciences Curriculum Study, Boulder, CO.

The experimental 1973-74 edition of Unit V consists of 35 life science curriculum activities intended for 13- to 16-year-old educable mentally handicapped adolescents. The role of the teacher in continuing field trials is noted and environmental themes and elements, inquiry skills, problem solving skills, and applicational behaviors and attitudes…

Promoting School Success. Third Edition

ERIC Educational Resources Information Center

Lovitt, Thomas C.

2007-01-01

Like its two predecessors, "Preventing School Dropouts" [C1991] and "Preventing School Failure" [C2000], this third edition is a book about teaching. Although primarily written for teachers, tutors and parents may also find this book helpful. It is a collection of carefully selected teaching techniques aimed at helping young adults learn important…

Process Instrumentation. Teacher Edition.

ERIC Educational Resources Information Center

Brown, A. O., III; Fowler, Malcolm

This module provides instructional materials that are designed to help teachers train students in job skills for entry-level jobs as instrumentation technicians. This text addresses the basics of troubleshooting control loops, and the transducers, transmitters, signal conditioners, control valves, and controllers that enable process systems to…

State Teacher Policy Yearbook: Progress on Teacher Quality, 2007. Colorado State Summary

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2007

2007-01-01

The "State Teacher Policy Yearbook" examines what is arguably the single most powerful authority over the teaching profession: state government. This Colorado edition of the National Council on Teacher Quality's (NCTQ's) "State Teacher Policy Yearbook" is the first of what will be an annual look at the status of state policies…

Places Where Teachers Are Taught. First Edition.

ERIC Educational Resources Information Center

Goodlad, John I., Ed.; And Others

This book utilizes 29 case histories of geographically and institutionally diverse teacher education programs to provide a comprehensive historical perspective on teacher education in the United States. The volume, organized into four parts, is further divided into nine chapters. "Part One: "Teacher Education: A Contemporary Perspective…

Commercial and Industrial Wiring. Teacher Edition [and] Student Edition. Third Edition.

ERIC Educational Resources Information Center

Kaltwasser, Stan; Flowers, Gary; Aneke, Norbert O.

This revised curriculum guide for teachers and students includes the additional technical knowledge and applications required to help prepare students for job entry in the commercial and industrial wiring trade. The curriculum guide contains 16 units that cover the following topics: (1) blueprint reading and load calculations; (2) tools and…

Teacher Evaluation That Works!! Second Edition

ERIC Educational Resources Information Center

Ribas, William B.

2005-01-01

Creating a system for successfully supervising and evaluating the entire teaching staff of a school district is a daunting task. An effective system-wide program can only be achieved if the administrators, teachers and the teachers' association understand and attend to the educational, legal, public relations (political), and social-emotional…

Hands-On Life Science Activities for Middle Schools. Teacher's Edition. First Edition.

ERIC Educational Resources Information Center

Newman, Barbara; Kramer, Stephanie

This book provides 50 enrichment activities for the science curriculum that provide concrete connections with important world events. Each activity is self-contained and provides everything the student needs to gain a basic understanding of a concept or to work through a project. The activities include innovative and traditional projects for both…

Motorcycle Mechanic. Teacher Edition.

ERIC Educational Resources Information Center

Baugus, Mickey; Fulkerson, Dan, Ed.

These teacher's materials are for a 19-unit competency-based course on entry-level motorcycle mechanics at the secondary and postsecondary levels. The 19 units are: (1) introduction to motorcycle repair; (2) general safety; (3) tools and equipment; (4) metric measurements; (5) fasteners; (6) service department operations; (7) motorcycle engines;…

Snowmobile Repair. Teacher Edition.

ERIC Educational Resources Information Center

Hennessy, Stephen S.; Conrad, Rex

This teacher's guide contains 14 units on snowmobile repair: (1) introduction to snowmobile repair; (2) skis, front suspension, and steering; (3) drive clutch; (4) drive belts; (5) driven clutch; (6) chain drives; (7) jackshafts and axles; (8) rear suspension; (9) tracks; (10) shock absorbers; (11) brakes; (12) engines; (13) ignition and…

Water quality management library. 2. edition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eckenfelder, W.W.; Malina, J.F.; Patterson, J.W.

1998-12-31

A series of ten books offered in conjunction with Water Quality International, the Biennial Conference and Exposition of the International Association on Water Pollution Research and Control (IAWPRC). Volume 1, Activated Sludge Process, Design and Control, 2nd edition, 1998: Volume 2, Upgrading Wastewater Treatment Plants, 2nd edition, 1998: Volume 3, Toxicity Reduction, 2nd edition, 1998: Volume 4, Municipal Sewage Sludge Management, 2nd edition, 1998: Volume 5, Design and Retrofit of Wastewater Treatment Plants for Biological Nutrient Removal, 1st edition, 1992: Volume 6, Dynamics and Control of the Activated Sludge Process, 2nd edition, 1998: Volume 7: Design of Anaerobic Processes formore » the Treatment of Industrial and Municipal Wastes, 1st edition, 1992: Volume 8, Groundwater Remediation, 1st edition, 1992: Volume 9, Nonpoint Pollution and Urban Stormwater Management, 1st edition, 1995: Volume 10, Wastewater Reclamation and Reuse, 1st edition, 1998.« less

The Teacher and Integration. Revised Edition.

ERIC Educational Resources Information Center

Noar, Gertrude

This book is intended for both beginning and experienced teachers who face many difficult challenges in today's desegregated school. Teachers must come to feel and recognize the many contingencies of the desegregated classroom if it is to be a place for learning. Because social class segregates children as often as does race, the major question…

2014 Teacher Prep Review: A Review of the Nation's Teacher Preparation Programs

ERIC Educational Resources Information Center

Greenberg, Julie; Walsh, Kate; McKee, Arthur

2014-01-01

"Teacher Prep Review 2014" is the second edition of the National Council on Teacher Quality's (NCTQ's) annual assessment of the nation's 2,400 teacher prep programs. The "Review" uncovers early evidence that teacher prep programs are beginning to make changes. It arrives at a time of heightened, unprecedented…

Partial DNA-guided Cas9 enables genome editing with reduced off-target activity

PubMed Central

Yin, Hao; Song, Chun-Qing; Suresh, Sneha; Kwan, Suet-Yan; Wu, Qiongqiong; Walsh, Stephen; Ding, Junmei; Bogorad, Roman L; Zhu, Lihua Julie; Wolfe, Scot A; Koteliansky, Victor; Xue, Wen; Langer, Robert; Anderson, Daniel G

2018-01-01

CRISPR–Cas9 is a versatile RNA-guided genome editing tool. Here we demonstrate that partial replacement of RNA nucleotides with DNA nucleotides in CRISPR RNA (crRNA) enables efficient gene editing in human cells. This strategy of partial DNA replacement retains on-target activity when used with both crRNA and sgRNA, as well as with multiple guide sequences. Partial DNA replacement also works for crRNA of Cpf1, another CRISPR system. We find that partial DNA replacement in the guide sequence significantly reduces off-target genome editing through focused analysis of off-target cleavage, measurement of mismatch tolerance and genome-wide profiling of off-target sites. Using the structure of the Cas9–sgRNA complex as a guide, the majority of the 3′ end of crRNA can be replaced with DNA nucleotide, and the 5 - and 3′-DNA-replaced crRNA enables efficient genome editing. Cas9 guided by a DNA–RNA chimera may provide a generalized strategy to reduce both the cost and the off-target genome editing in human cells. PMID:29377001

State Teacher Policy Yearbook: Progress on Teacher Quality, 2007. New Jersey State Summary

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2007

2007-01-01

The "State Teacher Policy Yearbook" examines what is arguably the single most powerful authority over the teaching profession: state government. This New Jersey edition of the National Council on Teacher Quality's (NCTQ's) "State Teacher Policy Yearbook" is the first of what will be an annual look at the status of state…

State Teacher Policy Yearbook: Progress on Teacher Quality, 2007. New Mexico State Summary

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2007

2007-01-01

The "State Teacher Policy Yearbook" examines what is arguably the single most powerful authority over the teaching profession: state government. This New Mexico edition of the National Council on Teacher Quality's (NCTQ's) "State Teacher Policy Yearbook" is the first of what will be an annual look at the status of state…

State Teacher Policy Yearbook: Progress on Teacher Quality, 2007. New Hampshire State Summary

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2007

2007-01-01

The "State Teacher Policy Yearbook" examines what is arguably the single most powerful authority over the teaching profession: state government. This New Hampshire edition of the National Council on Teacher Quality's (NCTQ's) "State Teacher Policy Yearbook" is the first of what will be an annual look at the status of state…

Going to the Market. Teacher Edition. Fashion Buying Series.

ERIC Educational Resources Information Center

Collins, Cindy

This teacher's guide presents material for a unit on attending the retail fashion market. Content focuses on previewing merchandise for purchase, factors involved in a major market trip, common terms used when ordering merchandise, and pricing strategies. The guide contains 4 objectives, 6 group learning activities keyed to the objectives, 12…

Introduction to Fashion Buying. Teacher Edition. Fashion Buying Series.

ERIC Educational Resources Information Center

Collins, Cindy

This teacher's guide presents material for a unit on introduction to fashion buying. Content focuses on information sources, retail store types, the responsibilities of a buyer, and the qualifications of a buyer. The guide contains 4 objectives, 4 group learning activities keyed to the objectives, 17 transparency masters with dialogue for each,…

Kentucky Teacher Preparation and Certification Handbook. 1983 Edition.

ERIC Educational Resources Information Center

Kentucky State Dept. of Education, Frankfort. Div. of Teacher Education and Certification.

This handbook includes teacher preparation and certification regulations adopted by the Kentucky State Board of Education through March 1983. State standards are delineated for: (1) statutory provisions relating to teacher education and certification; (2) teacher certification procedures; (3) ranking of teacher qualifications; (4) evaluation and…

Preparing for the Market. Teacher Edition. Fashion Buying Series.

ERIC Educational Resources Information Center

Collins, Cindy

This teacher's guide presents material for a unit on preparing for the retail fashion market. Content focuses on merchandise plans, computing open-to-buy, computing turnover, the components of a model stock plan, and criteria used when selecting a supplier. The guide contains 5 objectives, 6 group learning activities keyed to the objectives, 21…

Me and My Environment, Unit IV: Transfer and Cycling of Materials in My Environment, Experimental Edition 1973-74.

ERIC Educational Resources Information Center

Biological Sciences Curriculum Study, Boulder, CO.

The experimental 1973-74 edition of Unit IV consists of 28 life science curriculum activities for 13- to 16-year-old educable mentally handicapped children. The role of the teacher in continuing field trials is noted and environmental themes and elements, inquiry skills, problem solving skills, and applicational behaviors and attitudes are…

Kentucky Teacher Preparation and Certification Handbook. 1981 Edition.

ERIC Educational Resources Information Center

Kentucky State Dept. of Education, Frankfort.

This handbook sets forth the regulations of the Kentucky State Board of Education that relate to teacher education and certification. The following topics are covered: (1) selected statutory provisions relating to teacher education and certification; (2) teacher certification procedures; (3) ranking of teacher qualifications; (4) procedures for…

Multisensory Teaching of Basic Language Skills Activity Book. Revised Edition

ERIC Educational Resources Information Center

Carreker, Suzanne; Birsh, Judith R.

2011-01-01

With the new edition of this activity book--the companion to Judith Birsh's bestselling text, "Multisensory Teaching of Basic Language Skills"--students and practitioners will get the practice they need to use multisensory teaching effectively with students who have dyslexia and other learning disabilities. Ideal for both pre-service teacher…

Environments. Basic Edition. Science for Micronesia.

ERIC Educational Resources Information Center

Trust Territory of the Pacific Islands Dept. of Education, Saipan.

Presented is a teacher's guide to an elementary science unit designed for use with fourth grade, or higher, students in the Trust Territory of Micronesia. Although there is a degree of similarity to curriculum materials developed for the Science Curriculum Improvement Study, this Micronesian unit does not purport to be an adaption or edition of…

Populations. Basic Edition. Science for Micronesia.

ERIC Educational Resources Information Center

Trust Territory of the Pacific Islands Dept. of Education, Saipan.

This teacher's guide is for an elementary school science unit designed for use with third grade (or older) children in the Trust Territory of Micronesia. Although there is a degree of similarity to curriculum materials developed for the Science Curriculum Improvement Study, this Micronesian unit does not purport to be an adaptation or edition of…

Association of Guide RNA Binding Protein gBP21 with Active RNA Editing Complexes in Trypanosoma brucei

PubMed Central

Allen, Thomas E.; Heidmann, Stefan; Reed, RoseMary; Myler, Peter J.; Göringer, H. Ulrich; Stuart, Kenneth D.

1998-01-01

RNA editing in Trypanosoma brucei mitochondria produces mature mRNAs by a series of enzyme-catalyzed reactions that specifically insert or delete uridylates in association with a macromolecular complex. Using a mitochondrial fraction enriched for in vitro RNA editing activity, we produced several monoclonal antibodies that are specific for a 21-kDa guide RNA (gRNA) binding protein initially identified by UV cross-linking. Immunofluorescence studies localize the protein to the mitochondrion, with a preference for the kinetoplast. The antibodies cause a supershift of previously identified gRNA-specific ribonucleoprotein complexes and immunoprecipitate in vitro RNA editing activities that insert and delete uridylates. The immunoprecipitated material also contains gRNA-specific endoribonuclease, terminal uridylyltransferase, and RNA ligase activities as well as gRNA and both edited and unedited mRNA. The immunoprecipitate contains numerous proteins, of which the 21-kDa protein, a 90-kDa protein, and novel 55- and 16-kDa proteins can be UV cross-linked to gRNA. These studies indicate that the 21-kDa protein associates with the ribonucleoprotein complex (or complexes) that catalyze RNA editing. PMID:9742118

Adolescents at School: Perspectives on Youth, Identity, and Education. Second Edition

ERIC Educational Resources Information Center

Sadowski, Michael, Ed.

2008-01-01

As any teacher or parent knows, adolescence is a time when youth grapple with the question, "Who am I?" Issues of race, ethnicity, class, gender, sexual orientation, and ability can complicate this question for young people, affecting their schoolwork and their relationships with teachers, family, and peers. This new edition of "Adolescents at…

Introduction to Natural Resources. Second Edition. [Teacher Edition and Student Edition Combined.

ERIC Educational Resources Information Center

Crummett, Dan

These student and teacher guides are designed for a secondary-level course in natural resources that focuses on renewable and nonrenewable natural resources, methods of protecting the environment, and the various careers and technologies available in the natural resources area. The following topics are covered in the course's 10 units: outdoor…

Enlivening Secondary History: 50 Classroom Activities for Teachers and Pupils. Second Edition

ERIC Educational Resources Information Center

Davies, Peter; Davies, Rhys

2012-01-01

"Enlivening Secondary History" is the ideal handbook for busy history teachers who want to do something different in their classrooms, but have little time to plan and organise their lessons. Featuring tried-and-tested practical ideas complete with relevant exemplars and step-by-step advice, this best-selling book is a compendium of creative…

Teacher's Guide to Animal Camouflage: The MATCH Box Project; Prototype Edition.

ERIC Educational Resources Information Center

Standring, Gillian; Bernath, Robert

The Materials and Activities for Teachers and Children (MATCH Box) project was developed in 1965 to provide for the relatively intensive treatment of a subject over a short period through materials geared to the elementary school level. Each MATCH Box contains materials, equipment, and activities that work together to foster the teaching/learning…

State Teacher Policy Yearbook: What States Can Do to Retain Effective New Teachers, 2008. Alabama

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2008

2008-01-01

This paper presents the Alabama edition of the National Council on Teacher Quality's 2008 "State Teacher Policy Yearbook". The 2008 "Yearbook" focuses on how state policies impact the retention of effective new teachers. This policy evaluation is broken down into three areas that encompass 15 goals. Broadly, these goals examine…

State Teacher Policy Yearbook: What States Can Do to Retain Effective New Teachers, 2008. Idaho

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2008

2008-01-01

This report presents the Idaho edition of the National Council on Teacher Quality's 2008 "State Teacher Policy Yearbook." The 2008 "Yearbook" focuses on how state policies impact the retention of effective new teachers. This policy evaluation is broken down into three areas that encompass 15 goals. Broadly, these goals examine…

Best Practices in Literacy Instruction. Second Edition.

ERIC Educational Resources Information Center

Morrow, Lesley Mandel, Ed.; Gambrell, Linda B., Ed.; Pressley, Michael, Ed.

Now revised and updated, this book's second edition aims to guide teachers in providing effective, engaging literacy instruction that meets the challenges of today's legislative mandates. Identified in the book are principles of best practice that reflect cutting-edge scientific research as well as decades of hands-on classroom experience.…

How the Brain Learns: A Classroom Teacher's Guide. Second Edition.

ERIC Educational Resources Information Center

Sousa, David A.

This book presents information to help teachers turn research on brain function into practical classroom activities and lessons, offering: brain facts; information on how the brain processes information; tips on maximizing retention; an information processing model that reflects new terminology regarding the memory systems; new research on how the…

Teacher's Guide to the Algonquins: The MATCH Box Project; Prototype Edition.

ERIC Educational Resources Information Center

Butler, Eva; And Others

What better way is there to learn about something than to hold it, examine it, and take it apart? The Match Box Project (Materials and Activities for Teachers and Children) loans to schools a series of boxes which contain materials, equipment, supplies, and activities designed as a unit to foster the teaching/learning of specific subjects at the…

A Revised Guide for Improving Teacher Education in Human Rights.

ERIC Educational Resources Information Center

Phi Delta Kappa, Bloomington, IN. Commission of Education, Human Rights, and Responsibilities.

This document serves as a guide for teacher education institutions and programs designed to prepare educators for meeting their responsibilities in the area of human rights and human relations. This second edition of the guide represents a substantial modification of the original guide, and includes many activities, experiences, and suggestions…

State Teacher Policy Yearbook: What States Can Do to Retain Effective New Teachers, 2008. South Carolina

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2008

2008-01-01

This paper presents the South Carolina edition of the National Council on Teacher Quality's 2008 "State Teacher Policy Yearbook". The 2008 "Yearbook" focuses on how state policies impact the retention of effective new teachers. This policy evaluation is broken down into three areas that encompass 15 goals. Broadly, these goals…

State Teacher Policy Yearbook: What States Can Do to Retain Effective New Teachers, 2008. New Mexico

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2008

2008-01-01

This paper presents the New Mexico edition of the National Council on Teacher Quality's 2008 "State Teacher Policy Yearbook". The 2008 "Yearbook" focuses on how state policies impact the retention of effective new teachers. This policy evaluation is broken down into three areas that encompass 15 goals. Broadly, these goals…

State Teacher Policy Yearbook: What States Can Do to Retain Effective New Teachers, 2008. New Jersey

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2008

2008-01-01

This paper presents the New Jersey edition of the National Council on Teacher Quality's 2008 "State Teacher Policy Yearbook". The 2008 "Yearbook" focuses on how state policies impact the retention of effective new teachers. This policy evaluation is broken down into three areas that encompass 15 goals. Broadly, these goals…

State Teacher Policy Yearbook: What States Can Do to Retain Effective New Teachers, 2008. New Hampshire

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2008

2008-01-01

This paper presents the New Hampshire edition of the National Council on Teacher Quality's 2008 "State Teacher Policy Yearbook". The 2008 "Yearbook" focuses on how state policies impact the retention of effective new teachers. This policy evaluation is broken down into three areas that encompass 15 goals. Broadly, these goals…

Fundamentals of Welding. Teacher Edition.

ERIC Educational Resources Information Center

Fortney, Clarence; And Others

These instructional materials assist teachers in improving instruction on the fundamentals of welding. The following introductory information is included: use of this publication; competency profile; instructional/task analysis; related academic and workplace skills list; tools, materials, and equipment list; and 27 references. Seven units of…

Editing activity for eliminating mischarged tRNAs is essential in mammalian mitochondria

PubMed Central

Hilander, Taru; Zhou, Xiao-Long; Konovalova, Svetlana; Zhang, Fu-Ping; Euro, Liliya; Chilov, Dmitri; Poutanen, Matti; Chihade, Joseph

2018-01-01

Abstract Accuracy of protein synthesis is enabled by the selection of amino acids for tRNA charging by aminoacyl-tRNA synthetases (ARSs), and further enhanced by the proofreading functions of some of these enzymes for eliminating tRNAs mischarged with noncognate amino acids. Mouse models of editing-defective cytoplasmic alanyl-tRNA synthetase (AlaRS) have previously demonstrated the importance of proofreading for cytoplasmic protein synthesis, with embryonic lethal and progressive neurodegeneration phenotypes. Mammalian mitochondria import their own set of nuclear-encoded ARSs for translating critical polypeptides of the oxidative phosphorylation system, but the importance of editing by the mitochondrial ARSs for mitochondrial proteostasis has not been known. We demonstrate here that the human mitochondrial AlaRS is capable of editing mischarged tRNAs in vitro, and that loss of the proofreading activity causes embryonic lethality in mice. These results indicate that tRNA proofreading is essential in mammalian mitochondria, and cannot be overcome by other quality control mechanisms. PMID:29228266

The Law of Teacher Evaluation. Second Edition.

ERIC Educational Resources Information Center

Rossow, Lawrence F.; Tate, James O.

This monograph is a legal treatise covering all legal aspects of the evaluation of teachers. It looks at what can legally be evaluated, how the evaluation can become evidence for termination, and how to avoid and win lawsuits involving wrongful teacher dismissals. It is intended for practicing administrators, supervisors of instruction, teacher…

The High School Mathematics Library. Eighth Edition.

ERIC Educational Resources Information Center

Schaaf, William L.

This eighth edition of the bibliography reflects changes in emphasis in the secondary school mathematics curriculum. The booklet is addressed primarily to high school students of all ability levels and to their mathematics teachers, and should also be of interest to students and instructors of mathematics in two-year colleges as well as librarians…

Enriching Student Teaching Relationships. Student Teacher Edition.

ERIC Educational Resources Information Center

Clothier, Grant; Kingsley, Elizabeth

This document seeks to enable student teachers to deal more effectively with their cooperating teachers. The student teaching situation can be a time of stress for the student because of the abrupt change to near-professional status, the experience of being closely supervised by another person in foreign territory, and the knowledge that his…

Introduction to Instrumentation. Teacher Edition.

ERIC Educational Resources Information Center

Brown, A. O., III

This module contains instructional materials on instrumentation to help teachers train students in the job skills they will need as beginning instrumentation technicians. The module addresses the nature of accessing, measuring, and controlling phenomena such as level, flow, pressure, and temperature. Students are introduced to the devices and…

SCDC Spanish Curricula Units. Science/Math Strand, Unit 5, Grade 2, Teacher's Guide--Multi-Ethnic Edition.

ERIC Educational Resources Information Center

Operations Research Society of America, Arlington, VA.

Continuing the theme of the school as a community, the teacher's guide to the science/math strand of unit five presents both instructional and assessment activities for kits 17-20. Focus, materials and objective for each activity are in Spanish and English; teacher instructions are in Spanish only. In kit 17 the science activities deal with the…

Small Business Management. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This instructor's guide, which is designed to assist teachers in providing instruction and technical support to small business owners and managers, contains 17 competency-based units of instruction on the following areas that both small business instructors and small business owners have deemed critical to the success of any business:…

Guest-Service Agent. Teacher Edition.

ERIC Educational Resources Information Center

Al-Harake, Mounzer

This teacher's guide for the hospitality and tourism industry is designed to include the entry-level competencies students will need to enter any of the occupational areas identified in the front-desk section of the lodging occupations cluster. These occupations include front-desk clerk, cashier, telephone operator, guest-service agent,…

Literature for Today's Young Adults. Fourth Edition.

ERIC Educational Resources Information Center

Nilsen, Alleen Pace; Donelson, Kenneth L.

Designed to help teachers open young minds to literature, this book presents criteria for evaluating books in all genres and their suggested classroom uses, an examination of hotly debated topics, and an overview of the significance of young adult literature. The fourth edition of the book features 30 boxed inserts containing essays by some of the…

A Model for Flexibly Editing CSCL Scripts

ERIC Educational Resources Information Center

Sobreira, Pericles; Tchounikine, Pierre

2012-01-01

This article presents a model whose primary concern and design rationale is to offer users (teachers) with basic ICT skills an intuitive, easy, and flexible way of editing scripts. The proposal is based on relating an end-user representation as a table and a machine model as a tree. The table-tree model introduces structural expressiveness and…

Material Objects. Basic Edition. Science for Micronesia.

ERIC Educational Resources Information Center

Trust Territory of the Pacific Islands Dept. of Education, Saipan.

Presented is a teacher's guide for an elementary science unit designed for use with first grade students in the Trust Territory of Micronesia. Although there is a degree of similarity to the curriculum materials developed for the Science Curriculum Improvement Study, this Micronesian unit does not purport to be an adaptation or edition of the SCIS…

Counseling Skills for Teachers

ERIC Educational Resources Information Center

Kottler, Jeffrey A.; Kottler, Ellen

2006-01-01

By necessity, today's teachers do much more than deliver instruction. In the classroom, on the playground, or even in the parking lot, teachers are often called upon to respond quickly and appropriately to students' social and emotional needs, drawing from instinct more than anything else. In this second edition of "Counseling Skills for…

Resource Book for Drug Abuse Education. Second Edition.

ERIC Educational Resources Information Center

Nellis, Muriel, Ed.

This second edition of the "Resource Book" assembles a selection of scientific, philosophical, and educational drug abuse literature. The publication, as viewed by its authors, serves as a basis for improved understanding, trust, and communication between teacher and student concerning drug use and its place in both contemporary youth culture and…

Biotechnology in Agriculture. Teacher Edition.

ERIC Educational Resources Information Center

Peterson, Dennis R.; Rehberger, Thomas

This curriculum guide is designed to help teachers to present a course that emphasizes the interrelationship of science and technology and the impact of this technology on agriculture and agricultural products. The guide contains six units that each contain some or all of the following basic components of a unit of instruction: objective sheet,…

Decay and Renewal. Teacher Edition.

ERIC Educational Resources Information Center

Trautmann, Nancy M.; Krasny, Marianne E.; Carlsen, William S.; Cunningham, Christine M.; Canning, Harry; Carroll, Patricia; Johnson, Mark; Khandar, Alpa; Olynciw, Elaina; Kottler, Bennett; Penningroth, Stephen; Welman, Adam

This teacher guide is part of the Environmental Inquiry (EI) curriculum series developed at Cornell University to enable high school students to conduct authentic environmental science research. The goals of EI are for students to: (1) develop research skills; (2) use their newly acquired skills to conduct research projects of their own design,…

Microwave Oven Repair. Teacher Edition.

ERIC Educational Resources Information Center

Smreker, Eugene

This competency-based curriculum guide for teachers addresses the skills a technician will need to service microwave ovens and to provide customer relations to help retain the customer's confidence in the product and trust in the service company that performs the repair. The guide begins with a task analysis, listing 20 cognitive tasks and 5…

Food Production, Management and Services: Service. Teacher Edition. Second Edition.

ERIC Educational Resources Information Center

Palan, Earl

This food production, management, and services teacher guide contains nine units: (1) orientation; (2) types of service; (3) table settings; (4) dining room personnel; (5) dining room procedures; (6) side work; (7) guest/employee relationships; (8) sales techniques; and (9) safety and sanitation. Suggestions are included to increase reinforcement…

State Teacher Policy Yearbook, 2009. National Summary

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The 2009 edition of the "State Teacher Policy Yearbook" is the National Council on Teacher Quality's (NCTQ's) third annual review of state laws, rules and regulations that govern the teaching profession. This year's report is a comprehensive analysis of the full range of each state's teacher policies, measured against a realistic…

Food Production, Management, and Services. Production. Teacher Edition. Second Edition.

ERIC Educational Resources Information Center

Gibson, LeRoy

This teacher's guide contains 20 units of instruction for a course in production in the food production, management, and services area. Units of instruction are designed for use in more than one lesson or class period of instruction. Introductory materials include the following: a competency profile; instructional/task analysis; related academic…

State Teacher Policy Yearbook, 2011. National Summary

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2011

2011-01-01

The year 2011 was no ordinary year for teacher policy. In fact, it was a year like no other chronicled by the National Council on Teacher Quality's (NCTQ) "State Teacher Policy Yearbook". This fifth annual edition of the Yearbook documents more changes in state teacher policy than NCTQ has seen in any of its previous top-to-bottom reviews of the…

CRISPR Epigenome Editing of AKAP150 in DRG Neurons Abolishes Degenerative IVD-Induced Neuronal Activation.

PubMed

Stover, Joshua D; Farhang, Niloofar; Berrett, Kristofer C; Gertz, Jason; Lawrence, Brandon; Bowles, Robby D

2017-09-06

Back pain is a major contributor to disability and has significant socioeconomic impacts worldwide. The degenerative intervertebral disc (IVD) has been hypothesized to contribute to back pain, but a better understanding of the interactions between the degenerative IVD and nociceptive neurons innervating the disc and treatment strategies that directly target these interactions is needed to improve our understanding and treatment of back pain. We investigated degenerative IVD-induced changes to dorsal root ganglion (DRG) neuron activity and utilized CRISPR epigenome editing as a neuromodulation strategy. By exposing DRG neurons to degenerative IVD-conditioned media under both normal and pathological IVD pH levels, we demonstrate that degenerative IVDs trigger interleukin (IL)-6-induced increases in neuron activity to thermal stimuli, which is directly mediated by AKAP and enhanced by acidic pH. Utilizing this novel information on AKAP-mediated increases in nociceptive neuron activity, we developed lentiviral CRISPR epigenome editing vectors that modulate endogenous expression of AKAP150 by targeted promoter histone methylation. When delivered to DRG neurons, these epigenome-modifying vectors abolished degenerative IVD-induced DRG-elevated neuron activity while preserving non-pathologic neuron activity. This work elucidates the potential for CRISPR epigenome editing as a targeted gene-based pain neuromodulation strategy. Copyright © 2017 The American Society of Gene and Cell Therapy. Published by Elsevier Inc. All rights reserved.

Genome Editing Tools in Plants

PubMed Central

Mohanta, Tapan Kumar; Bashir, Tufail; Hashem, Abeer; Bae, Hanhong

2017-01-01

Genome editing tools have the potential to change the genomic architecture of a genome at precise locations, with desired accuracy. These tools have been efficiently used for trait discovery and for the generation of plants with high crop yields and resistance to biotic and abiotic stresses. Due to complex genomic architecture, it is challenging to edit all of the genes/genomes using a particular genome editing tool. Therefore, to overcome this challenging task, several genome editing tools have been developed to facilitate efficient genome editing. Some of the major genome editing tools used to edit plant genomes are: Homologous recombination (HR), zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), pentatricopeptide repeat proteins (PPRs), the CRISPR/Cas9 system, RNA interference (RNAi), cisgenesis, and intragenesis. In addition, site-directed sequence editing and oligonucleotide-directed mutagenesis have the potential to edit the genome at the single-nucleotide level. Recently, adenine base editors (ABEs) have been developed to mutate A-T base pairs to G-C base pairs. ABEs use deoxyadeninedeaminase (TadA) with catalytically impaired Cas9 nickase to mutate A-T base pairs to G-C base pairs. PMID:29257124

Traffic Flow - USMES Teacher Resource Book. Fourth Edition. Trial Edition.

ERIC Educational Resources Information Center

Keskulla, Jean

This Unified Sciences and Mathematics for Elementary Schools (USMES) unit challenges students to improve traffic flow at a problem location. The challenge is general enough to apply to many problem-solving situations in mathematics, science, social science, and language arts at any elementary school level (grades 1-8). The Teacher Resource Book…

Characteristics of Effective Teachers--A Clarifying Activity.

ERIC Educational Resources Information Center

Ford, Jerry D.

An activity, developed to assist preservice teachers to clarify their understanding of teacher effectiveness and the role of a teacher training program, uses a list, given to each student, of words that may be used to describe an effective teacher: fair, honest, friendly, knowledgeable, organized, prepared, articulate, creative, well-groomed,…

Protein synthesis editing by a DNA aptamer.

PubMed Central

Hale, S P; Schimmel, P

1996-01-01

Potential errors in decoding genetic information are corrected by tRNA-dependent amino acid recognition processes manifested through editing reactions. One example is the rejection of difficult-to-discriminate misactivated amino acids by tRNA synthetases through hydrolytic reactions. Although several crystal structures of tRNA synthetases and synthetase-tRNA complexes exist, none of them have provided insight into the editing reactions. Other work suggested that editing required active amino acid acceptor hydroxyl groups at the 3' end of a tRNA effector. We describe here the isolation of a DNA aptamer that specifically induced hydrolysis of a misactivated amino acid bound to a tRNA synthetase. The aptamer had no effect on the stability of the correctly activated amino acid and was almost as efficient as the tRNA for inducing editing activity. The aptamer has no sequence similarity to that of the tRNA effector and cannot be folded into a tRNA-like structure. These and additional data show that active acceptor hydroxyl groups in a tRNA effector and a tRNA-like structure are not essential for editing. Thus, specific bases in a nucleic acid effector trigger the editing response. Images Fig. 3 Fig. 4 PMID:8610114

The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis

PubMed Central

Gumireddy, Kiranmai; Li, Anping; Kossenkov, Andrew V.; Sakurai, Masayuki; Yan, Jinchun; Li, Yan; Xu, Hua; Wang, Jian; Zhang, Paul J.; Zhang, Lin; Showe, Louise C.; Nishikura, Kazuko; Huang, Qihong

2016-01-01

Metastasis is a critical event affecting breast cancer patient survival. To identify molecules contributing to the metastatic process, we analysed The Cancer Genome Atlas (TCGA) breast cancer data and identified 41 genes whose expression is inversely correlated with survival. Here we show that GABAA receptor alpha3 (Gabra3), normally exclusively expressed in adult brain, is also expressed in breast cancer, with high expression of Gabra3 being inversely correlated with breast cancer survival. We demonstrate that Gabra3 activates the AKT pathway to promote breast cancer cell migration, invasion and metastasis. Importantly, we find an A-to-I RNA-edited form of Gabra3 only in non-invasive breast cancers and show that edited Gabra3 suppresses breast cancer cell invasion and metastasis. A-to-I-edited Gabra3 has reduced cell surface expression and suppresses the activation of AKT required for cell migration and invasion. Our study demonstrates a significant role for mRNA-edited Gabra3 in breast cancer metastasis. PMID:26869349

The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis.

PubMed

Gumireddy, Kiranmai; Li, Anping; Kossenkov, Andrew V; Sakurai, Masayuki; Yan, Jinchun; Li, Yan; Xu, Hua; Wang, Jian; Zhang, Paul J; Zhang, Lin; Showe, Louise C; Nishikura, Kazuko; Huang, Qihong

2016-02-12

Metastasis is a critical event affecting breast cancer patient survival. To identify molecules contributing to the metastatic process, we analysed The Cancer Genome Atlas (TCGA) breast cancer data and identified 41 genes whose expression is inversely correlated with survival. Here we show that GABAA receptor alpha3 (Gabra3), normally exclusively expressed in adult brain, is also expressed in breast cancer, with high expression of Gabra3 being inversely correlated with breast cancer survival. We demonstrate that Gabra3 activates the AKT pathway to promote breast cancer cell migration, invasion and metastasis. Importantly, we find an A-to-I RNA-edited form of Gabra3 only in non-invasive breast cancers and show that edited Gabra3 suppresses breast cancer cell invasion and metastasis. A-to-I-edited Gabra3 has reduced cell surface expression and suppresses the activation of AKT required for cell migration and invasion. Our study demonstrates a significant role for mRNA-edited Gabra3 in breast cancer metastasis.

High GC Content Cas9-Mediated Genome-Editing and Biosynthetic Gene Cluster Activation in Saccharopolyspora erythraea.

PubMed

Liu, Yong; Wei, Wen-Ping; Ye, Bang-Ce

2018-05-18

The overexpression of bacterial secondary metabolite biosynthetic enzymes is the basis for industrial overproducing strains. Genome editing tools can be used to further improve gene expression and yield. Saccharopolyspora erythraea produces erythromycin, which has extensive clinical applications. In this study, the CRISPR-Cas9 system was used to edit genes in the S. erythraea genome. A temperature-sensitive plasmid containing the PermE promoter, to drive Cas9 expression, and the Pj23119 and PkasO promoters, to drive sgRNAs, was designed. Erythromycin esterase, encoded by S. erythraea SACE_1765, inactivates erythromycin by hydrolyzing the macrolactone ring. Sequencing and qRT-PCR confirmed that reporter genes were successfully inserted into the SACE_1765 gene. Deletion of SACE_1765 in a high-producing strain resulted in a 12.7% increase in erythromycin levels. Subsequent PermE- egfp knock-in at the SACE_0712 locus resulted in an 80.3% increase in erythromycin production compared with that of wild type. Further investigation showed that PermE promoter knock-in activated the erythromycin biosynthetic gene clusters at the SACE_0712 locus. Additionally, deletion of indA (SACE_1229) using dual sgRNA targeting without markers increased the editing efficiency to 65%. In summary, we have successfully applied Cas9-based genome editing to a bacterial strain, S. erythraea, with a high GC content. This system has potential application for both genome-editing and biosynthetic gene cluster activation in Actinobacteria.

Trypanosoma brucei RNA Editing Complex

PubMed Central

O'Hearn, Sean F.; Huang, Catherine E.; Hemann, Mike; Zhelonkina, Alevtina; Sollner-Webb, Barbara

2003-01-01

Maturation of Trypanosoma brucei mitochondrial mRNA involves massive posttranscriptional insertion and deletion of uridine residues. This RNA editing utilizes an enzymatic complex with seven major proteins, band I through band VII. We here use RNA interference (RNAi) to examine the band II and band V proteins. Band II is found essential for viability; it is needed to maintain the normal structure of the editing complex and to retain the band V ligase protein. Previously, band III was found essential for certain activities, including maintenance of the editing complex and retention of the band IV ligase protein. Thus, band II and band V form a protein pair with features analogous to the band III/band IV ligase pair. Since band V is specific for U insertion and since band IV is needed for U deletion, their parallel organization suggests that the editing complex has a pseudosymmetry. However, unlike the essential band IV ligase, RNAi to band V has only a morphological but no growth rate effect, suggesting that it is stimulatory but nonessential. Indeed, in vitro analysis of band V RNAi cell extract demonstrates that band IV can seal U insertion when band V is lacking. Thus, band IV ligase is the first activity of the basic editing complex shown able to serve in both forms of editing. Our studies also indicate that the U insertional portion may be less central in the editing complex than the corresponding U deletional portion. PMID:14560033

Cas9 gRNA engineering for genome editing, activation and repression

DOE PAGES

Kiani, Samira; Chavez, Alejandro; Tuttle, Marcelle; ...

2015-09-07

Here we demonstrate that by altering the length of Cas9-associated guide RNA(gRNA) we were able to control Cas9 nuclease activity and simultaneously perform genome editing and transcriptional regulation with a single Cas9 protein. We exploited these principles to engineer mammalian synthetic circuits with combined transcriptional regulation and kill functions governed by a single multifunctional Cas9 protein.

Beyond the Wasteland: The Criticism of Broadcasting. Revised Edition.

ERIC Educational Resources Information Center

Smith, Robert Rutherford

This second edition of "Beyond the Wasteland" provides an updated review of broadcast criticism. It offers teachers information to sharpen their own critical capacities and help for exploring media criticism with their students. It also provides suggestions and contextual insights for the mass media researcher. The book is divided into…

Leading the Teacher Induction and Mentoring Program. Second Edition

ERIC Educational Resources Information Center

Sweeny, Barry W.

2007-01-01

While resources are abundant for helping the mentor and the new teacher, very little has been written to guide the leaders of teacher and mentor development. This book provides an effective, proven model for developing, implementing, evaluating, and sustaining an induction and mentoring program that results in highly qualified teachers. A…

How To Help Beginning Teachers Succeed. 2nd Edition.

ERIC Educational Resources Information Center

Gordon, Stephen P.; Maxey, Susan

This book explores the reasons that beginning teachers struggle and provides research-based plans for helping them make the most of their initial teaching years. It proposes Beginning Teacher Assistance Programs (BTAPs) as a practical strategy for success. BTAPs draw on the knowledge and expertise of teachers, principals, central office…

Key Data on Teaching Languages at School in Europe. 2008 Edition

ERIC Educational Resources Information Center

Baidak, Nathalie; Parveva, Teodora

2008-01-01

This second edition of "Key Data on Teaching Languages at School in Europe" contains 44 indicators in five chapters entitled "Context," "Organisation," "Participation," "Teachers" and "Teaching Processes." It has been produced in collaboration with Eurostat and belongs to the "Key…

Book Review: New Perspectives on Technical Editing

NASA Astrophysics Data System (ADS)

Murphy, A. J. (Ed.); Sterken, Christiaan

2012-08-01

New Perspectives on Technical Editing by Avon J. Murphy (ed.) ISBN : 978-0895033949 (2010) Baywood Publishing Company Inc, Hardcover, 210 pages, 35.5 GBP This book presents a collection of 10 chapters dealing with diverse aspects of technical editing (ie, editorial planning, and analysis and structural changes made to other people's technological documents): research in technical editing, trends and teaching of technical editing, copyediting, and technical journal editing. The role and function of the modern journal and book editor is also dealt with in detail. Each chapter is written by an expert in the field: senior editors, university professors in technical communication, technical writers and linguists. The ever-evolving role of the editor is clearly elucidated in several historical reviews, and in the descriptions of the expectations for the future. A very striking aspect of this book is its extensive collection of bibliographic resources: every chapter lists dozens of very useful references, and the closing chapter, and annotated bibliography, contain many not so well known references, and are most useful. All in all, the book is a treasure trove listing more than 400 references, in addition to numerous webpage URLs embedded in the texts. The book is designed to help the reader to understand current practices and norms in technical editing, and to help to take action in editing as well as in teaching and educating would-be editors. The audience for this book thus includes editors and teachers, but also writers, researchers and students. A deep reading of this book will result in a better understanding of the difference between full technical editing and its much narrower component so well known as copyediting, and will convince any prospective editor that editing should not be undertaken if the people involved do not master the art of precision and accuracy in technical (as well as in human) communication, do not possess the technical know how and computer

Adult Learning Methods: A Guide for Effective Instruction. Second Edition.

ERIC Educational Resources Information Center

Galbraith, Michael W., Ed.

This book contains 21 papers devoted to understanding and facilitating adult learning. After "Foreword to the Second Edition" (Malcolm S. Knowles) and other introductory materials, the papers are: "Becoming an Effective Teacher of Adults" (Michael W. Galbraith); "Understanding Adult Learners" (Huey B. Long); "Identifying Your Philosophical…

Drafting. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials for drafting for students in grades 6-10 consists of an instructor's section and student materials. The instructor's section contains background information, suggested activities, and a list of suggested resources. A lesson plan for the 8-day module includes assignments; equipment, tools,…

Lasers. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This document contains the materials required for presenting an 8-day competency-based technology learning activity (TLA) designed to introduce students in grades 6-10 to advances and career opportunities in the field of laser technology. The guide uses a series of hands-on exploratory experiences into which activities to help students develop…

The levels of edit, second edition

NASA Technical Reports Server (NTRS)

Vanburen, R.; Buehler, M. F.

1980-01-01

The editorial process is analyzed, and five levels of edit are identified. These levels represent cumulative combinations of nine types of edit: Coordination, Policy, Integrity, Screening, Copy Clarification, Format, Mechanical Style, Language, and Substantive. The levels and types of edit, although developed for specific use with external reports at the Jet Propulsion Laboratory, cover the general range of technical editing, especially as it applies to an in-house technical publications organization. Each type of edit is set forth in terms of groups of actions to be performed by editor. The edit-level concept has enhanced understanding and communication among editors, authors, and publications managers concerning the specific editorial work to be done on each manuscript. It has also proved useful as a management tool for estimating and monitoring cost.

Occupational Investigation. Teacher's Handbook. First Edition.

ERIC Educational Resources Information Center

East Texas State Univ., Commerce. Occupational Curriculum Lab.

This teacher's handbook provides suggestions for organization and presentation of resource and instructional materials found in four occupational investigation guides available separately (see Note). Chapter 1 explains Texas Education Agency operations and the Occupational Investigation program and policies. Chapter 2 discusses public relations…

Photography. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum guide provides technology learning activities designed to prepare students in grades 6-10 to work in the world of the future. The 8-day course provides exploratory, hands-on learning activities and information that can enhance the education of students of all types in an integrated curriculum that provides practical applications of…

Cellphones in Classrooms Land Teachers on Online Video Sites

ERIC Educational Resources Information Center

Honawar, Vaishali

2007-01-01

Videos of teachers that students taped in secrecy are all over online sites like YouTube and MySpace. Angry teachers, enthusiastic teachers, teachers clowning around, singing, and even dancing are captured, usually with camera phones, for the whole world to see. Some students go so far as to create elaborately edited videos, shot over several…

Good Questions: Great Ways to Differentiate Mathematics Instruction in the Standards-Based Classroom. Third Edition

ERIC Educational Resources Information Center

Small, Marian

2017-01-01

Now in its Third Edition--expanded with over 100 new tasks and questions--this bestselling resource helps experienced and novice teachers to effectively and efficiently differentiate mathematics instruction in grades K-8. Math education expert Marian Small shows teachers how to get started and become expert at using two powerful and universal…

Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish

PubMed Central

Porath, Hagit T.; Barak, Michal; Pinto, Yishay; Wachtel, Chaim; Zilberberg, Alona; Lerer-Goldshtein, Tali; Efroni, Sol; Levanon, Erez Y.; Appelbaum, Lior

2015-01-01

Fragile X syndrome (FXS) is the most frequent inherited form of mental retardation. The cause for this X-linked disorder is the silencing of the fragile X mental retardation 1 (fmr1) gene and the absence of the fragile X mental retardation protein (Fmrp). The RNA-binding protein Fmrp represses protein translation, particularly in synapses. In Drosophila, Fmrp interacts with the adenosine deaminase acting on RNA (Adar) enzymes. Adar enzymes convert adenosine to inosine (A-to-I) and modify the sequence of RNA transcripts. Utilizing the fmr1 zebrafish mutant (fmr1-/-), we studied Fmrp-dependent neuronal circuit formation, behavior, and Adar-mediated RNA editing. By combining behavior analyses and live imaging of single axons and synapses, we showed hyperlocomotor activity, as well as increased axonal branching and synaptic density, in fmr1-/- larvae. We identified thousands of clustered RNA editing sites in the zebrafish transcriptome and showed that Fmrp biochemically interacts with the Adar2a protein. The expression levels of the adar genes and Adar2 protein increased in fmr1-/- zebrafish. Microfluidic-based multiplex PCR coupled with deep sequencing showed a mild increase in A-to-I RNA editing levels in evolutionarily conserved neuronal and synaptic Adar-targets in fmr1-/- larvae. These findings suggest that loss of Fmrp results in increased Adar-mediated RNA editing activity on target-specific RNAs, which, in turn, might alter neuronal circuit formation and behavior in FXS. PMID:26637167

A Rainforest Child. An Active Learning Pack for 8-13 Year Olds [Second Edition.

ERIC Educational Resources Information Center

Lyle, Sue; Roberts, Maggy

This resource packet includes a teacher's guide, reproducible student worksheets, posters, activity cards, and a music audiotape: "Song of the Forest," with a booklet of lyrics. The teacher's guide suggests interdisciplinary activities which meet the United Kingdom's National Curriculum requirements and encourage active learning as…

Teacher's Guide to Paddle-to-the-Sea: The MATCH Box Project; Prototype Edition.

ERIC Educational Resources Information Center

Bever, Buz; Kresse, Frederick H.

The Materials and Activities for Teachers and Children (MATCH Box) project provides for a two-week intensive treatment of a subject on the elementary school level. Each MATCH Box contains materials, equipment and activities that work together to foster the teaching/learning of the particular subject matter. PADDLE-TO-THE-SEA is a social studies…

Diesel Technology: Electrical and Electronic Systems. Teacher Edition [and] Student Edition.

ERIC Educational Resources Information Center

Ready, Allan; Kauffman, Ricky; Bogle, Jerry

This document contains the materials for a competency-based course in diesel technology and electrical and electronic systems that is tied to measurable and observable learning outcomes identified and validated by an advisory committee of business and industry representatives and teachers. The competencies addressed align with the medium/heavy…

Changing genetic information through RNA editing

NASA Technical Reports Server (NTRS)

Maas, S.; Rich, A.

2000-01-01

RNA editing, the post-transcriptional alteration of a gene-encoded sequence, is a widespread phenomenon in eukaryotes. As a consequence of RNA editing, functionally distinct proteins can be produced from a single gene. The molecular mechanisms involved include single or multiple base insertions or deletions as well as base substitutions. In mammals, one type of substitutional RNA editing, characterized by site-specific base-modification, was shown to modulate important physiological processes. The underlying reaction mechanism of substitutional RNA editing involves hydrolytic deamination of cytosine or adenosine bases to uracil or inosine, respectively. Protein factors have been characterized that are able to induce RNA editing in vitro. A supergene family of RNA-dependent deaminases has emerged with the recent addition of adenosine deaminases specific for tRNA. Here we review the developments that have substantially increased our understanding of base-modification RNA editing over the past few years, with an emphasis on mechanistic differences, evolutionary aspects and the first insights into the regulation of editing activity.

Teachers' Professional Agency and Learning--From Adaption to Active Modification in the Teacher Community

ERIC Educational Resources Information Center

Pyhältö, Kirsi; Pietarinen, Janne; Soini, Tiina

2015-01-01

The aim of this study was to examine teacher learning in terms of teachers' professional agency in the professional community of the school. Altogether 2310 Finnish comprehensive school teachers completed a survey. Results showed that teachers' active efforts to learn in the professional community and to promote school development cannot be…

Bread in a Bag. Teacher's Packet. Revised Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Education, Oklahoma City.

This unit is designed to familiarize students in grades 3-6 with wheat production; teach them the nutritional value of wheat products and their role in a well-balanced diet; and give then an easy, hands-on experience in bread making with a nominal amount of cleanup for teachers. The kit suggests that in the first week, teachers discuss wheat…

State Teacher Policy Yearbook, 2009. Connecticut

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This Connecticut edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

State Teacher Policy Yearbook, 2009. Tennessee

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This Tennessee edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

Basics of Desktop Publishing. Teacher Edition.

ERIC Educational Resources Information Center

Beeby, Ellen

This color-coded teacher's guide contains curriculum materials designed to give students an awareness of various desktop publishing techniques before they determine their computer hardware and software needs. The guide contains six units, each of which includes some or all of the following basic components: objective sheet, suggested activities…

Pipe Drafting with CAD. Teacher Edition.

ERIC Educational Resources Information Center

Smithson, Buddy

This teacher's guide contains nine units of instruction for a course on computer-assisted pipe drafting. The course covers the following topics: introduction to pipe drafting with CAD (computer-assisted design); flow diagrams; pipe and pipe components; valves; piping plans and elevations; isometrics; equipment fabrication drawings; piping design…

Food Service Management. Second Edition. Answer Book/Teacher's Guide. Second Edition.

ERIC Educational Resources Information Center

Hatchett, Melvin S.; Zelade, Richard

This document contains a student assignment book with 22 assignments for a course in food service management and a teacher's guide with answers to the assignments and tips on presenting the lessons to which they pertain. The assignments cover the following topics: career opportunities; entering the food service industry; classifications of…

Elementary School Teachers' Perception of Desirable Learning Activities: A Singaporean Perspective.

ERIC Educational Resources Information Center

Tan, Ai-girl

2001-01-01

From ratings of children's learning activities by 209 elementary teachers in Singapore, four factors emerged: conventional activities, motivational activities, student-directed activities that foster independence and collaboration, and teacher-directed group activities. Beginning teachers preferred motivational activities. The current environment…

Educating Children with Multiple Disabilities: A Collaborative Approach. Fourth Edition

ERIC Educational Resources Information Center

Orelove, Fred P., Ed.; Sobsey, Dick, Ed.; Silberman, Rosanne K., Ed.

2004-01-01

Now in its fourth edition, this highly respected, bestselling textbook gives undergraduate and graduate students up-to-the-minute research and strategies for educating children with severe and multiple disabilities. This popular core text--for 15 years, a staple of teacher training programs in special education and related fields--thoroughly…

1001 Best Internet Sites for Educators. 2nd Edition.

ERIC Educational Resources Information Center

Treadwell, Mark

This second edition of a resource designed to help teachers find relevant information on the Internet for both themselves and their students, provides concise reviews of more than 1,000 Web sites sorted by subject area. Each site is evaluated with one to five stars for content, presentation and grade level. Easy-to-follow explanations are provided…

LdShake: Learning Design Solutions Sharing and Co-Edition

ERIC Educational Resources Information Center

Hernandez-Leo, Davinia; Romeo, Lauren; Carralero, Miguel A.; Chacon, Jonathan; Carrio, Mar; Moreno, Pau; Blat, Josep

2011-01-01

Two important challenges that teachers are currently facing are the sharing and the collaborative authoring of their learning design solutions, such as didactical units and learning materials. On the one hand, there are tools that can be used for the creation of design solutions and only some of them facilitate the co-edition. However, they do not…

The Read-Aloud Handbook. Fourth Edition. Revised and Updated.

ERIC Educational Resources Information Center

Trelease, Jim

This new edition of a guide which has made reading aloud a special pleasure for millions of people offers a chance for a new generation of parents, teachers, grandparents, and siblings to discover the rewards--and the necessity--of reading aloud. The guide provides an up-to-date annotated bibliography ("treasury") of more than 1200…

Introduction to Natural Resources. Teacher Edition.

ERIC Educational Resources Information Center

Hehn, Darold; Newport, Bob

This color-coded teacher's guide contains curriculum materials designed to help students develop an awareness of renewable and nonrenewable natural resources and to identify occupations in the area of natural resources. The guide contains nine units, each of which includes some or all of the following basic components: objective sheet, suggested…

Technology for Teachers. 6th Edition.

ERIC Educational Resources Information Center

Volker, Roger; Simonson, Michael

This book helps teachers learn how to use and make educational media, covering traditional and new media such as computer laboratories, authentic assessment, theory bases, and hypermedia. Chapter topics progress from simple to complex. Each chapter includes clearly stated behavioral objectives that provide a study guide for students and can serve…

Contextualizing Teacher Professionalism: Findings from a Cross-Case Analysis of Union Active Teachers

ERIC Educational Resources Information Center

Osmond-Johnson, Pamela

2016-01-01

This paper draws on data collected as part of a study of the discourses of teacher professionalism amongst union active teachers in the Canadian provinces of Alberta and Ontario. Interviews revealed a triad of influences on the professionalism discourses of participants: engagement in teacher associations, the larger policy environment, and…

Classroom Archaeology: An Archaeology Activity Guide for Teachers. Third Edition.

ERIC Educational Resources Information Center

Hawkins, Nancy W.

This guide describes archaeology activities appropriate for middle school students, but some activities can be used in intermediate and primary grades or high school and college classes. The activities range in length from less than one hour to 15 hours. A sequence of activities may be used together as a unit on archaeology, or individual…

State Teacher Policy Yearbook, 2009. Hawaii

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The Hawaii edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Idaho

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The Idaho edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Utah

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This Utah edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Maine

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This Maine edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Alaska

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The Alaska edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Kansas

ERIC Educational Resources Information Center

Rosen, Kelli M.; Madden, Trisha M.; Maltz, Stephanie T.; Myers-Preston, Tracey L.

2009-01-01

This Kansas edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Kentucky

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The Kentucky edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. Iowa

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The Iowa edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

Active Learning Promoting Student Teachers' Professional Competences in Finland and Turkey

ERIC Educational Resources Information Center

Niemi, Hannele; Nevgi, Anne; Aksit, Fisun

2016-01-01

This study investigates student teachers' active learning experiences in teacher education (TE) in Finnish and Turkish contexts and attempts to determine how active learning methods' impact student teachers' professional competences. Student teachers (N = 728) assessed their active learning experiences and the professional competences they…

Science: A Practical View. Volume I. Teacher Edition. Applied Basic Curriculum Series.

ERIC Educational Resources Information Center

Evaluation, Dissemination and Assessment Center, Dallas.

This guide, the first in a series of three, provides the intermediate science student and teacher an opportunity to review selected science concepts and processes through activities which emphasize the applicability of scientific knowledge in the professional world. The three components in this guide deal with (1) ecology (what marine science…

Solar Energy Education. Industrial arts: teacher's guide. Field test edition. [Includes glossary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

An instructional aid is presented which integrates the subject of solar energy into the classroom study of industrial arts. This guide for teachers was produced in addition to the student activities book for industrial arts by the USDOE Solar Energy Education. A glossary of solar energy terms is included. (BCS)

America's Hero to the World, George C. Marshall. Teacher's Guide. Second Edition [and] Resource Packet [and] George C. Marshall: An American Leader. A Teacher's Notebook.

ERIC Educational Resources Information Center

Thompson, Rachel Yarnell; Sittig, Linda H.

This teaching unit about George C. Marshall contains a teacher's guide, a resource packet, and a teacher's notebook. The teacher's guide includes ten introductory, overarching, and culminating activities: (1) About this Guide; (2) Getting to Know Him; (3) Marshal on Video; (4) Share a Space with a Hero; (5) On a Global Stage--Links; (6) A Picture…

Beyond Discipline: From Compliance to Community. 10th Anniversary Edition

ERIC Educational Resources Information Center

Kohn, Alfie

2006-01-01

In this 10th anniversary edition of an Association for Supervision and Curriculum Development (ASCD) best seller, the author reflects on his revolutionary ideas in the context of today's emphasis on school accountability and high-stakes testing. The author relates how his innovative approach--where teachers learn to work with students, rather than…

Collaborative Work and Language Learners' Identities When Editing Academic Texts

ERIC Educational Resources Information Center

Caviedes, Lorena; Meza, Angélica; Rodriguez, Ingrid

2016-01-01

This paper presents a qualitative case study that involved three groups of English as a foreign language pre-service teachers at a Colombian private university. Each group attended tutoring sessions during an academic semester. Along these sessions, students were asked to work collaboratively in the editing process of some chapters of their thesis…

Behavioral Talk-Write as a Method for Teaching Technical Editing.

ERIC Educational Resources Information Center

Gilbertsen, Michael; Killingsworth, M. Jimmie

1987-01-01

Presents a process-oriented method for teachers of stylistic editing workshops that allows them to (1) focus on individual students, (2) start with students basic repertory of responses and build from there, (3) work with freely emitted behavior, (4) ensure frequent and brief responses, and (5) achieve desired behavior through sequential steps.…

High/Scope Buyer's Guide to Children's Software. 11th Edition.

ERIC Educational Resources Information Center

Hohmann, Charles; And Others

This 11th edition of the High/Scope Buyer's Guide to Children's Software was designed to help teachers, caregivers, and parents make good choices when purchasing software to enhance children's learning. The book consists of an introduction, a chapter on finding the best software, software reviews for 48 different software products. The…

Job stressors and job stress among teachers engaged in nursing activity.

PubMed

Muto, Shigeki; Muto, Takashi; Seo, Akihiko; Yoshida, Tsutomu; Taoda, Kazushi; Watanabe, Misuzu

2007-01-01

Teachers and staff members engaged in nursing activity experience more stress than other workers. However, it is unknown whether teachers engaged in nursing activity in schools for handicapped children experience even greater stress. This study evaluated job stressors and job stress among such teachers using a cross-sectional study design. The subjects were all 1,461 teachers from all 19 prefectural schools for handicapped children in Shizuoka Prefecture, Japan. We used a brief job stress questionnaire for the survey and 831 teachers completed the questionnaire. Job stressors among teachers engaged in nursing activity were compared with those among teachers not engaged in nursing activity. Job stress among such teachers was estimated by the score for total health risk, and was compared with the score in the Japanese general population. Male and female teachers engaged in nursing activity had a significantly higher level of job stressors for physical work load and job control compared with those not engaged in nursing activity. The scores for total health risk among male and female teachers engaged in nursing activity were 102 points and 98 points, respectively. These scores were not markedly above 100 points which is the mean score in the Japanese general population.

A Survey of Validation Strategies for CRISPR-Cas9 Editing.

PubMed

Sentmanat, Monica F; Peters, Samuel T; Florian, Colin P; Connelly, Jon P; Pruett-Miller, Shondra M

2018-01-17

The T7 endonuclease 1 (T7E1) mismatch detection assay is a widely used method for evaluating the activity of site-specific nucleases, such as the clustered regularly interspaced short palindromic repeats (CRISPR)-Cas9 system. To determine the accuracy and sensitivity of this assay, we compared the editing estimates derived by the T7E1 assay with that of targeted next-generation sequencing (NGS) in pools of edited mammalian cells. Here, we report that estimates of nuclease activity determined by T7E1 most often do not accurately reflect the activity observed in edited cells. Editing efficiencies of CRISPR-Cas9 complexes with similar activity by T7E1 can prove dramatically different by NGS. Additionally, we compared editing efficiencies predicted by the Tracking of Indels by Decomposition (TIDE) assay and the Indel Detection by Amplicon Analysis (IDAA) assay to that observed by targeted NGS for both cellular pools and single-cell derived clones. We show that targeted NGS, TIDE, and IDAA assays predict similar editing efficiencies for pools of cells but that TIDE and IDAA can miscall alleles in edited clones.

Jobs and Engines, Teacher's Guide: Political Issues. Comparing Political Experiences, Experimental Edition.

ERIC Educational Resources Information Center

Gillespie, Judith A.; Lazarus, Stuart

This teacher's guide to unit 5 of the 12th-grade second-semester "Comparing Political Experiences" course provides specific objectives and instructional procedures for each of the five activities that focus on the case study of the Cummins Engine Company. In addition, the guide provides instructions for coordinating the use of the…

"Teachers and Teaching": From Classroom to Reflection.

ERIC Educational Resources Information Center

Frankes, Lisa

1993-01-01

Book review recommends "Teachers and Teaching," edited by Tom Russell and Hugh Munby, to educators who envision a symbiosis of professional practice and research to promote teacher researchers, suggesting that the book's strength lies in its diversity of forms of enquiry--from narrative dialogs between educators, to case studies, to more…

Tape It Yourself: Videotapes for Teacher Education

ERIC Educational Resources Information Center

Ebsworth, Miriam Eistein; Feknous, Barbara; Loyet, Dianne; Zimmerman, Spencer

2004-01-01

This paper describes the development and implementation of a series of videotapes of ESL classes for a pre-service teacher education program grounded in experiential learning theory. The videos included footage of ESL classrooms, and tapes edited and supplemented with interviews of ESL teachers. Our experience demonstrates that-with relatively low…

Teacher feedback during active learning: current practices in primary schools.

PubMed

van den Bergh, Linda; Ros, Anje; Beijaard, Douwe

2013-06-01

Feedback is one of the most powerful tools, which teachers can use to enhance student learning. It appears difficult for teachers to give qualitatively good feedback, especially during active learning. In this context, teachers should provide facilitative feedback that is focused on the development of meta-cognition and social learning. The purpose of the present study is to contribute to the existing knowledge about feedback and to give directions to improve teacher feedback in the context of active learning. The participants comprised 32 teachers who practiced active learning in the domain of environmental studies in the sixth, seventh, or eighth grade of 13 Dutch primary schools. A total of 1,465 teacher-student interactions were examined. Video observations were made of active learning lessons in the domain of environmental studies. A category system was developed based on the literature and empirical data. Teacher-student interactions were assessed using this system. Results. About half of the teacher-student interactions contained feedback. This feedback was usually focused on the tasks that were being performed by the students and on the ways in which these tasks were processed. Only 5% of the feedback was explicitly related to a learning goal. In their feedback, the teachers were directing (rather than facilitating) the learning processes. During active learning, feedback on meta-cognition and social learning is important. Feedback should be explicitly related to learning goals. In practice, these kinds of feedback appear to be scarce. Therefore, giving feedback during active learning seems to be an important topic for teachers' professional development. © 2012 The British Psychological Society.

Teachers' Cognitive Activities and Overt Behaviors.

ERIC Educational Resources Information Center

Brophy, Jere E.

Recent research on teacher planning, thinking, and decision making is reviewed. The work on planning reveals that teachers typically do not use the objectives-based, rational models stressed in textbooks, but instead concentrate on the activities included in a curriculum as they seem to relate to the needs and interests of the students. This…

Adult and Family Living. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum guide for teachers is designed for use with 11th- and 12th-grade students who have had no more than 1 year of vocational home economics. It focuses on providing young adults with the knowledge and skills they need for healthy and positive adult and family lives. It includes 27 units in 8 sections as follows: (1) personal…

Illinois State Bar Association Law Day Activities Guide. 2001 Edition.

ERIC Educational Resources Information Center

Illinois State Bar Association, Springfield.

These law-related lessons and activities can facilitate participation in a Law Day program. Following an introduction, this activities guide is divided into these sections: "Tips for Teachers" ("What Can a Lawyer Add to the Classroom?"; "So You Have Been Asked to Speak to Kids about the Law"; "A Checklist for…

Nuclear Concepts & Technological Issues Institute: Teacher Activity Booklet.

ERIC Educational Resources Information Center

Davison, Candace C., Ed.; Lunetta, Lois W., Ed.

For many summers the Radiation Science and Engineering Center at Pennsylvania State University has been the site of a Nuclear Concepts and Technological Issues Institute for secondary school science teachers. As a culminating activity of the institute teachers develop lesson plans, laboratory experiments, demonstrations, or other activities and…

Targeted activation of diverse CRISPR-Cas systems for mammalian genome editing via proximal CRISPR targeting.

PubMed

Chen, Fuqiang; Ding, Xiao; Feng, Yongmei; Seebeck, Timothy; Jiang, Yanfang; Davis, Gregory D

2017-04-07

Bacterial CRISPR-Cas systems comprise diverse effector endonucleases with different targeting ranges, specificities and enzymatic properties, but many of them are inactive in mammalian cells and are thus precluded from genome-editing applications. Here we show that the type II-B FnCas9 from Francisella novicida possesses novel properties, but its nuclease function is frequently inhibited at many genomic loci in living human cells. Moreover, we develop a proximal CRISPR (termed proxy-CRISPR) targeting method that restores FnCas9 nuclease activity in a target-specific manner. We further demonstrate that this proxy-CRISPR strategy is applicable to diverse CRISPR-Cas systems, including type II-C Cas9 and type V Cpf1 systems, and can facilitate precise gene editing even between identical genomic sites within the same genome. Our findings provide a novel strategy to enable use of diverse otherwise inactive CRISPR-Cas systems for genome-editing applications and a potential path to modulate the impact of chromatin microenvironments on genome modification.

Targeted activation of diverse CRISPR-Cas systems for mammalian genome editing via proximal CRISPR targeting

PubMed Central

Chen, Fuqiang; Ding, Xiao; Feng, Yongmei; Seebeck, Timothy; Jiang, Yanfang; Davis, Gregory D.

2017-01-01

Bacterial CRISPR–Cas systems comprise diverse effector endonucleases with different targeting ranges, specificities and enzymatic properties, but many of them are inactive in mammalian cells and are thus precluded from genome-editing applications. Here we show that the type II-B FnCas9 from Francisella novicida possesses novel properties, but its nuclease function is frequently inhibited at many genomic loci in living human cells. Moreover, we develop a proximal CRISPR (termed proxy-CRISPR) targeting method that restores FnCas9 nuclease activity in a target-specific manner. We further demonstrate that this proxy-CRISPR strategy is applicable to diverse CRISPR–Cas systems, including type II-C Cas9 and type V Cpf1 systems, and can facilitate precise gene editing even between identical genomic sites within the same genome. Our findings provide a novel strategy to enable use of diverse otherwise inactive CRISPR–Cas systems for genome-editing applications and a potential path to modulate the impact of chromatin microenvironments on genome modification. PMID:28387220

We're Born to Learn: Using the Brain's Natural Learning Process to Create Today's Curriculum. Second Edition

ERIC Educational Resources Information Center

Smilkstein, Rita

2011-01-01

This updated edition of the bestselling book on the brain's natural learning process brings new research results and applications in a power-packed teacher tool kit. Rita Smilkstein shows teachers how to create and deliver curricula that help students become the motivated, successful, and natural learners they were born to be. Updated features…

A hammerhead ribozyme substrate and reporter for in vitro kinetoplastid RNA editing.

PubMed Central

Wang, Bingbing; Salavati, Reza; Heidmann, Stefan; Stuart, Kenneth

2002-01-01

Current in vitro assays for RNA editing in kinetoplastids directly examine the products generated by incubation of pre-mRNA substrate with guide RNA (gRNA) and mitochondrial (mt) extract. RNA editing substrates that are modeled on hammerhead ribozymes were designed with catalytic cores that contained or lacked additional uridylates (Us). They proved to be sensitive reporters of editing activity when used for in vitro assays. A deletion editing substrate that is based on A6 pre-mRNA had no ribozyme activity, but its incubation with gRNA and mt extract resulted in its deletion editing and production of a catalytically active ribozyme. Hammerhead ribozymes are thus sensitive tools to assay in vitro RNA editing. PMID:11991648

Strategies That Work: Teaching Comprehension for Understanding and Engagement, Second Edition

ERIC Educational Resources Information Center

Harvey, Stephanie; Goudvis, Anne

2007-01-01

Since its publication in 2000, Strategies That Work has become an indispensable resource for teachers who want to explicitly teach thinking strategies so that students become engaged, thoughtful, independent readers. In this revised and expanded edition, the authors have added twenty completely new comprehension lessons, extending the scope of the…

Discipline with Dignity, 3rd Edition: New Challenges, New Solutions

ERIC Educational Resources Information Center

Curwin, Richard L.; Mendler, Allen N.; Mendler, Brian D.

2008-01-01

Since 1988, this landmark publication has given thousands of teachers timeless advice on not only how to prevent and solve discipline problems but also how to teach discipline as an affirming approach that promotes respect for self and others. Now this expanded 20th Anniversary Edition extends the authors' wisdom to new principles for coping with…

Recombination Narratives to Accompany "A-LM French One," First Edition.

ERIC Educational Resources Information Center

Coughlin, Dorothy

Supplementary recombination narratives intended for use with the 1961 edition of the text "A-LM French One" are designed to help students learn to manipulate basic textual materials. The sample narratives correlate with Units 4-14 of the text. The teacher is urged to make use of the overhead projector when using the narratives for the…

State Teacher Policy Yearbook, 2009. New Mexico

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This New Mexico edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

State Teacher Policy Yearbook, 2009. New Hampshire

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This New Hampshire edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

State Teacher Policy Yearbook, 2009. South Carolina

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This South Carolina edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

State Teacher Policy Yearbook, 2009. New Jersey

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This New Jersey edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

State Teacher Policy Yearbook, 2009. North Carolina

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This North Carolina edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

State Teacher Policy Yearbook, 2009. New York

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The New York edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on teacher…

State Teacher Policy Yearbook, 2009. South Dakota

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

This South Dakota edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive impact on…

Therapeutic gene editing: delivery and regulatory perspectives.

PubMed

Shim, Gayong; Kim, Dongyoon; Park, Gyu Thae; Jin, Hyerim; Suh, Soo-Kyung; Oh, Yu-Kyoung

2017-06-01

Gene-editing technology is an emerging therapeutic modality for manipulating the eukaryotic genome by using target-sequence-specific engineered nucleases. Because of the exceptional advantages that gene-editing technology offers in facilitating the accurate correction of sequences in a genome, gene editing-based therapy is being aggressively developed as a next-generation therapeutic approach to treat a wide range of diseases. However, strategies for precise engineering and delivery of gene-editing nucleases, including zinc finger nucleases, transcription activator-like effector nuclease, and CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats-associated nuclease Cas9), present major obstacles to the development of gene-editing therapies, as with other gene-targeting therapeutics. Currently, viral and non-viral vectors are being studied for the delivery of these nucleases into cells in the form of DNA, mRNA, or proteins. Clinical trials are already ongoing, and in vivo studies are actively investigating the applicability of CRISPR/Cas9 techniques. However, the concept of correcting the genome poses major concerns from a regulatory perspective, especially in terms of safety. This review addresses current research trends and delivery strategies for gene editing-based therapeutics in non-clinical and clinical settings and considers the associated regulatory issues.

Therapeutic gene editing: delivery and regulatory perspectives

PubMed Central

Shim, Gayong; Kim, Dongyoon; Park, Gyu Thae; Jin, Hyerim; Suh, Soo-Kyung; Oh, Yu-Kyoung

2017-01-01

Gene-editing technology is an emerging therapeutic modality for manipulating the eukaryotic genome by using target-sequence-specific engineered nucleases. Because of the exceptional advantages that gene-editing technology offers in facilitating the accurate correction of sequences in a genome, gene editing-based therapy is being aggressively developed as a next-generation therapeutic approach to treat a wide range of diseases. However, strategies for precise engineering and delivery of gene-editing nucleases, including zinc finger nucleases, transcription activator-like effector nuclease, and CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats-associated nuclease Cas9), present major obstacles to the development of gene-editing therapies, as with other gene-targeting therapeutics. Currently, viral and non-viral vectors are being studied for the delivery of these nucleases into cells in the form of DNA, mRNA, or proteins. Clinical trials are already ongoing, and in vivo studies are actively investigating the applicability of CRISPR/Cas9 techniques. However, the concept of correcting the genome poses major concerns from a regulatory perspective, especially in terms of safety. This review addresses current research trends and delivery strategies for gene editing-based therapeutics in non-clinical and clinical settings and considers the associated regulatory issues. PMID:28392568

Awakening the Sleeping Giant: Helping Teachers Develop as Leaders. Second Edition.

ERIC Educational Resources Information Center

Katzenmayer, Marilyn; Moller, Gayle

This book presents updated research on and examples of teacher leadership, offering practical tips for educators at all levels, tools for self-assessment, and a new vision of the future. The eight chapters are: (1) "What Is Teacher Leadership?" (e.g., definition of teacher leadership, roles for teacher leaders, and who is responsible); (2)…

Rhode Island Model Evaluation & Support System: Teacher. Edition III

ERIC Educational Resources Information Center

Rhode Island Department of Education, 2015

2015-01-01

Rhode Island educators believe that implementing a fair, accurate, and meaningful educator evaluation and support system will help improve teaching and learning. The primary purpose of the Rhode Island Model Teacher Evaluation and Support System (Rhode Island Model) is to help all teachers improve. Through the Model, the goal is to help create a…

Child's Play: An Activities and Materials Handbook.

ERIC Educational Resources Information Center

Trencher, Barbara R.

This handbook, the third printing of the original 1976 edition, presents an eclectic combination of activities gathered from parents and teachers of preschool children, with a focus on the process rather than the product of learning. Its goal is the establishment of positive experiences and sound interpersonal relationships between adults and…

Japan in the Classroom: Elementary and Secondary Activities, Revised Edition.

ERIC Educational Resources Information Center

Parisi, Lynn; And Others

This activity book is designed to present information and insights on Japanese culture and society. Because few teachers can devote entire units to the study of Japan, the activities focus on teaching about Japan within the context of larger social science units. Some of the lessons can be taught within the context of the humanities and fine arts,…

The Economy of Energy Conservation in Educational Facilities. A Report. Revised Edition.

ERIC Educational Resources Information Center

Educational Facilities Labs., Inc., New York, NY.

This is an update of the 1973 edition of a guide for energy conservation in schools. This Educational Facilities Laboratories publication is an information source for teachers, school administrators, school maintenance personnel, school designers, or anyone interested in conserving energy in schools. Topics discussed include: (1) life-cycle…

Woman's "True" Profession: Voices from the History of Teaching. 2nd Edition

ERIC Educational Resources Information Center

Hoffman, Nancy

2003-01-01

A rich and fascinating portrait of education life in America between 1830 and 1920, "Woman's 'True' Profession" is an indispensable contribution to our understanding of the teaching profession. "Women have always been teachers." So begins this second edition of Nancy Hoffman's classic history of women and the teaching…

"You're Going to Love This Kid!" Teaching Students with Autism in the Inclusive Classroom, Second Edition

ERIC Educational Resources Information Center

Kluth, Paula

2010-01-01

Thousands of educators have turned to "You're Going to Love this Kid!" for fresh ways to welcome and teach students with autism--and now the book teachers trust is fully revised and more practical than ever! Gathering feedback from teachers across the country during her popular workshops, autism expert Paula Kluth targeted this second edition to…

Entrepreneurship. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on entrepreneurship for students in grades 6-10 consists of a technology education overview, information on use, and instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections are…

Seven Steps You Can Take to Improve Your Objectives. Third Edition.

ERIC Educational Resources Information Center

Alvir, Claire Gelinas

This document gives examples of seven steps a classroom teacher can take to improve both instructional and learning objectives. This improvement is to be measured by increased student learning. The seven steps are as follows: a) write a simple behavioral objective, b) edit, c) revise objective to make it learner centered, d) clarify, e) evaluate…

Residential Construction. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials for residential construction for students in grades 6-10 consists of an instructor's section and student materials. The instructor's section contains background information, suggested activities, and a list of suggested resources. A lesson plan for the 10-day module includes assignments;…

State Teacher Policy Yearbook, 2009. District of Columbia

ERIC Educational Resources Information Center

National Council on Teacher Quality, 2009

2009-01-01

The District of Columbia edition of the National Council on Teacher Quality's (NCTQ's) 2009 "State Teacher Policy Yearbook" is the third annual look at state policies impacting the teaching profession. It is hoped that this report will help focus attention on areas where state policymakers can make changes that will have a positive…

Mapping Inner Space: Learning and Teaching Visual Mapping. Second Edition.

ERIC Educational Resources Information Center

Margulies, Nancy

More than 10 years ago, when "Mapping Inner Space" was first published, a few teachers were using this creative technique and teaching it to their students. Today mapping is widely used in schools, universities, and the corporate world, as well. This second edition of the book explores a variety of mapping styles and also takes a fresh look at the…

Controlled flexibility in technical editing - The levels-of-edit concept at JPL

NASA Technical Reports Server (NTRS)

Buehler, M. F.

1977-01-01

The levels-of-edit concept, which can be used to specify the amount of editorial effort involved in the preparation of a manuscript for publication, is discussed. Nine types of editing are identified and described. These include coordination edit (preparing estimates, gathering cost data, monitoring production processes), policy edit, integrity edit (making sure that parts of a publication match in a physical or numerical sense), screening edit (ensuring that the quality of camera-ready copy is sufficient for external publication), copy clarification edit, format edit, mechanical style edit, language edit, and substantive edit (reviewing the manuscript for content coherence, emphasis, subordination and parallelism). These functions are grouped into five levels of edit. An edit-level number is assigned to each manuscript, providing a quantitative and qualitative indicator of the editing to be done which is clearly understood by authors, managers, and editors alike. In addition, clear boundaries are drawn between normal and extraordinary editing tasks. Individual organizations will group various edits in different ways to reflect their needs and priorities; the essential element of the system is unambiguous definition and coding of the types and amount of work to be done.

Problem Solving. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum guide provides technology learning activities designed to prepare students in grades 6-10 to work in the world of the future. The 8-day course provides exploratory, hands-on learning activities and information that can enhance the education of students of all types in an integrated curriculum that provides practical applications of…

Structural Engineering. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum guide provides technology learning activities designed to prepare students in grades 6-10 to work in the world of the future. The 8-day course provides exploratory, hands-on learning activities and information that can enhance the education of students of all types in an integrated curriculum that provides practical applications of…

Control Robotics Programming Technology. Technology Learning Activity. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This Technology Learning Activity (TLA) for control robotics programming technology in grades 6-10 is designed to teach students to construct and program computer-controlled devices using a LEGO DACTA set and computer interface and to help them understand how control technology and robotics affect them and their lifestyle. The suggested time for…

How to Activate Teachers through Teacher Evaluation?

ERIC Educational Resources Information Center

Tuytens, Melissa; Devos, Geert

2014-01-01

There is a general doubt on whether teacher evaluation can contribute to teachers' professional development. Recently, standards-based teacher evaluation has been introduced in many countries to improve teaching practice. This study wants to investigate which teacher evaluation procedural, leadership, and teacher characteristics can stimulate…

Projections of Education Statistics to 2018. Thirty-Seventh Edition. NCES 2009-062

ERIC Educational Resources Information Center

Hussar, William J.; Bailey, Tabitha M.

2009-01-01

"Projections of Education Statistics to 2018" is the 37th report in a series begun in 1964. It includes statistics on elementary and secondary schools and degree-granting institutions. Included are projections of enrollment, graduates, teachers, and expenditures to the year 2018. This is the first edition of the "Projections of…

RNA Editing with CRISPR-Cas13

PubMed Central

Cox, David B.T.; Gootenberg, Jonathan S.; Abudayyeh, Omar O.; Franklin, Brian; Kellner, Max J.; Joung, Julia; Zhang, Feng

2017-01-01

Nucleic acid editing holds promise for treating genetic disease, particularly at the RNA level, where disease-relevant sequences can be rescued to yield functional protein products. Type VI CRISPR-Cas systems contain the programmable single-effector RNA-guided RNases Cas13. Here, we profile Type VI systems to engineer a Cas13 ortholog capable of robust knockdown and demonstrate RNA editing by using catalytically-inactive Cas13 (dCas13) to direct adenosine to inosine deaminase activity by ADAR2 to transcripts in mammalian cells. This system, referred to as RNA Editing for Programmable A to I Replacement (REPAIR), has no strict sequence constraints, can be used to edit full-length transcripts containing pathogenic mutations. We further engineer this system to create a high specificity variant, REPAIRv2, that is 919 times more specific than REPAIRv1 as well as minimize the system to ease viral delivery. REPAIR presents a promising RNA editing platform with broad applicability for research, therapeutics, and biotechnology. PMID:29070703

The Technique of Film Editing. Enlarged Edition.

ERIC Educational Resources Information Center

Reisz, Karel; Millar, Gavin

Film editing is discussed from the point of view, not only of the person in the cutting room, but also of the person who has responsibility for the final film. Part I outlines the history of editing from the silent film to 1953. It discusses the practice of editing for action, dialogue, comedy, and montage sequences, as well as in documentaries,…

A Tale of 2 Teachers: A Preschool Physical Activity Intervention Case Study.

PubMed

Howie, Erin K; Brewer, Alisa E; Dowda, Marsha; McIver, Kerry L; Saunders, Ruth P; Pate, Russell R

2016-01-01

Preschool settings vary greatly, and research has shown that interventions are more successful when they can be adapted to individual settings. This is a descriptive case study of how 2 teachers successfully adapted and implemented a preschool physical activity intervention. The Study of Health and Activity in Preschool Environments (SHAPES) was a 3-year physical activity intervention. A detailed case study of 2 high-implementing teachers was conducted. Multiple data sources included accelerometry, direct observation, teacher surveys, and intervention staff field notes. Teacher A focused on integrating physical activity into a wide range of activities, including parent and community events. Teacher B focused on high-intensity, structured activities. Both teachers supported the intervention, worked closely with intervention staff, and operated their classroom as an autonomous unit with support from their directors. Teacher A provided an average of 31.5, 78.0, and 67.5 min of physical activity opportunity per day of observation during years 1, 2, and 3. Teacher B provided an average of 2.7, 33.5, and 73.3 minutes of physical activity opportunity per day of observation. Successful implementation of physical activity interventions may look different in different contexts; thus, interventions should allow for flexible implementation. © 2015, American School Health Association.

A Tale of Two Teachers: A Preschool Physical Activity Intervention Case Study

PubMed Central

Howie, Erin K.; Brewer, Alisa E.; Dowda, Marsha; McIver, Kerry L.; Saunders, Ruth P.; Pate, Russell R.

2016-01-01

BACKGROUND Preschool settings vary greatly, and research has shown that interventions are more successful when they can be adapted to individual settings. This is a descriptive case study of how two teachers successfully adapted and implemented a preschool physical activity intervention. METHODS The Study of Health and Activity in Preschool Environments (SHAPES) was a three-year physical activity intervention. A detailed case study of two high-implementing teachers was conducted. Multiple data sources included accelerometry, direct observation, teacher surveys and intervention staff field notes. RESULTS Teacher A focused on integrating physical activity into a wide range of activities, including parent and community events. Teacher B focused on high-intensity, structured activities. Both teachers supported the intervention, worked closely with intervention staff, and operated their classroom as an autonomous unit with support from their directors. Teacher A provided an average of 31.5, 78.0 and 67.5 minutes of physical activity opportunity per day of observation during Years 1, 2, and 3. Teacher B provided an average of 2.7, 33.5, and 73.3 minutes of physical activity opportunity per day of observation. CONCLUSION Successful implementation of physical activity interventions may look different in different contexts; thus, interventions should allow for flexible implementation. PMID:26645417

Diesel Technology: Engines. [Teacher and Student Editions.

ERIC Educational Resources Information Center

Barbieri, Dave; Miller, Roger; Kellum, Mary

Competency-based teacher and student materials on diesel engines are provided for a diesel technology curriculum. Seventeen units of instruction cover the following topics: introduction to engine principles and procedures; engine systems and components; fuel systems; engine diagnosis and maintenance. The materials are based on the…

Challenging Science and Literacy Activities for K-9 Students - The Cricket Chronicles: Student Edition

ERIC Educational Resources Information Center

Matthews, Catherine E.

2006-01-01

This is an extensive integrated unit of study focused on that common and familiar insect-the cricket. In this edition, students are provided with more than 30 activities on crickets, which will help them learn science content and skills including: (1) Taxonomy; (2) Anatomy; (3) Ecology; (4) Mark and recapture techniques for estimating population…

From Teacher to Writer: How Does It Happen?

ERIC Educational Resources Information Center

Lewis, Barbara A.

1992-01-01

Discusses a sixth grade teacher's experience in turning a classroom project into a book. Offers advice for teachers on becoming writers. Explores obstacles, benefits, and suggestions on writing, editing, and publishing work. Describes a class project that resulted in the cleanup of a toxic waste site and the publication of "The Kid's Guide to…

Teachers Learning: Professional Development and Education. Cambridge Education Research Series

ERIC Educational Resources Information Center

McLaughlin, Colleen, Ed.

2012-01-01

"Teachers Learning: Professional Development and Education" is part of The Cambridge Education Research series, edited by senior colleagues at the University of Cambridge Faculty of Education, which has a longstanding tradition of involvement in high quality, innovative teacher education and continuing professional development.…

Physical and postural aspects of teachers during work activity.

PubMed

da Silva, Nilson Rogério; Almeida, Maria Amélia

2012-01-01

Studies indicate that teachers constitute a professional segment, in which the work characteristics and the demands originating from the act of teaching, favor the emergence of sickness, concerning physical or emotional aspects. The present work aimed to describe physical and postural aspects during the working activity of teachers. A total of 120 elementary school teachers (1st to 8th grade) took part in the survey. For data collection, a questionnaire was applied: it included personal and occupational information, perception of discomfort and being off work; physical strength activities; posture at work and physical conditioning activities. The average age of teachers of the present sample corresponds to 35,8 years. In relation to activities which generate more physical strength, the answer none of the activities was predominant with 30 answers; followed by writing on the board, standing up during the period of classes, explanation of the subjects, class elaboration, correction of homework and others. The area of the body with higher amount of occurrences and prevalent discomfort referred to the lower limbs and spinal cord. These data inform the necessity of investing in prevention programs for the teachers, in order to develop strategies into the organizational context and interventions at the work environment.

Learning Outcomes of Teacher Professional Development Activities: A Meta-Study

ERIC Educational Resources Information Center

Thurlings, Marieke; den Brok, Perry

2017-01-01

Former literature reviews suggested that if (student) teachers learn together in their professional development activities, professional development is enhanced. In the present literature review, we explored a variety of peer teacher professional development activities, conceptually divided into coaching, collaborating, and assessing activities.…

Contemporary Literacies and Technologies in English Language Arts Teacher Education: Shift Happens!

ERIC Educational Resources Information Center

George, Marshall; Pope, Carol; Reid, Louann

2015-01-01

Three leaders of the National Council of Teachers of English (NCTE) Conference on English Education (CEE) reflect on the changes that have occurred in English language arts teacher education in the past 15 years since the first edition of "Contemporary Issues in Technology and Teacher Education" ("CITE Journal") was published.…

Millennial Teachers of Color

ERIC Educational Resources Information Center

Dilworth, Mary E., Ed.

2018-01-01

"Millennial Teachers of Color" explores the opportunities and challenges for creating and sustaining a healthy teaching force in the United States. Millennials are the largest generational cohort in American history, with approximately ninety million members and, of these, roughly 43 percent are people of color. This book, edited by…

What do mathematics teachers and teacher trainees know about the history of mathematics?

NASA Astrophysics Data System (ADS)

Gazit, Avikam

2013-06-01

The aim of this study is to present the findings of a study that examined the knowledge of mathematics teachers and teacher trainees, in different tracks, about the concepts, topics and characters from the history of mathematics. The findings indicate a lack of knowledge concerning most of the topics examined. Only about 40% of the participants knew about the origin of our counting system and the only item that reached above 50% was the item relating to the man who edited the book which is the basis for the plane geometry - Euclid (about 83%). Another meaningful finding was that the group with the highest score was that of mathematics teacher trainees in the accelerated track - a unique training scheme for middle school teachers (65.7%). The group with the lowest score was that of the elementary school mathematics student teachers (19.3%). One obvious conclusion is that we need to strengthen the knowledge of the history of mathematics in teacher training and in-service teachers' advanced studies.

Teaching with Emotional Intelligence: A Step-By-Step Guide for Higher and Further Education Professionals. 2nd Edition

ERIC Educational Resources Information Center

Mortiboys, Alan

2011-01-01

The way teachers shape and handle their own feelings and those of their learners is central to the success of learning. Now in its second edition, "Teaching with Emotional Intelligence" shows how to manage this influential yet neglected area of learning and teaching. This practical book looks at how lecturers and teachers can develop and use their…

Gene Editing: Regulatory and Translation to Clinic.

PubMed

Ando, Dale; Meyer, Kathleen

2017-10-01

The clinical application and regulatory strategy of genome editing for ex vivo cell therapy is derived from the intersection of two fields of study: viral vector gene therapy trials; and clinical trials with ex vivo purification and engraftment of CD34 +  hematopoietic stem cells, T cells, and tumor cell vaccines. This article covers the regulatory and translational preclinical activities needed for a genome editing clinical trial modifying hematopoietic stem cells and the genesis of this current strategy based on previous clinical trials using genome-edited T cells. The SB-728 zinc finger nuclease platform is discussed because this is the most clinically advanced genome editing technology. Copyright © 2017 Elsevier Inc. All rights reserved.

Kaleidoscope: A Multicultural Booklist for Grades K-8. Third Edition. NCTE Bibliography Series.

ERIC Educational Resources Information Center

Yokota, Junko, Ed.

The third edition of this annotated bibliography collection offers students, teachers, and librarians a helpful guide to the best multicultural literature (published between 1996 and 1998) for elementary and middle school readers. With approximately 600 annotations on topics and formats including picture story books, realistic fiction, history and…

Trying to Contain Ourselves: A Dialogic Review of the "MLA Handbook, Eighth Edition"

ERIC Educational Resources Information Center

Walker, Janice R.; Kelly, Erin E.

2017-01-01

Since the 2016 release of the Modern Language Association's new style guidelines, scholars and teachers--along with writing centers, libraries, and editorial staffs--have been familiarizing themselves with the changes. Based on a standardized approach to citation, the eighth edition of the "MLA Handbook" asks us to adjust some…

Kaleidoscope: A Multicultural Booklist for Grades K-8. Fourth Edition. NCTE Bibliography Series.

ERIC Educational Resources Information Center

Hansen-Krening, Nancy, Ed.; Aoki, Elaine M., Ed.; Mizokawa, Donald T., Ed.

The fourth edition of this annotated bibliography collection offers students, teachers, and librarians a helpful guide to the best multicultural literature (published from 1999 to 2001) for elementary and middle school readers. The book continues a tradition of promoting unity through diversity by highlighting fiction and nonfiction published by…

Active Learning and Self-Regulation Enhance Student Teachers' Professional Competences

ERIC Educational Resources Information Center

Virtanen, Päivi; Niemi, Hannele M.; Nevgi, Anne

2017-01-01

The study identifies the relationships between active learning, student teachers' self-regulated learning and professional competences. Further, the aim is to investigate how active learning promotes professional competences of student teachers with different self-regulation profiles. Responses from 422 student teachers to an electronic survey…

Tuning of RNA editing by ADAR is required in Drosophila

PubMed Central

Keegan, Liam P; Brindle, James; Gallo, Angela; Leroy, Anne; Reenan, Robert A; O'Connell, Mary A

2005-01-01

RNA editing increases during development in more than 20 transcripts encoding proteins involved in rapid synaptic neurotransmission in Drosophila central nervous system and muscle. Adar (adenosine deaminase acting on RNA) mutant flies expressing only genome-encoded, unedited isoforms of ion-channel subunits are viable but show severe locomotion defects. The Adar transcript itself is edited in adult wild-type flies to generate an isoform with a serine to glycine substitution close to the ADAR active site. We show that editing restricts ADAR function since the edited isoform of ADAR is less active in vitro and in vivo than the genome-encoded, unedited isoform. Ubiquitous expression in embryos and larvae of an Adar transcript that is resistant to editing is lethal. Expression of this transcript in embryonic muscle is also lethal, with above-normal, adult-like levels of editing at sites in a transcript encoding a muscle voltage-gated calcium channel. PMID:15920480

Introduction to Hospitality and Tourism. Teacher Edition.

ERIC Educational Resources Information Center

Walker, Susan S.

This teacher's guide is the core publication of a series of instructional materials developed for the hospitality and tourism industry. It includes the entry-level competencies students will need to enter any of the occupational areas identified in the four cluster areas of the hospitality and tourism industry: lodging, food service, travel and…

Investigating the Activity Design and Development Skills of Geography Teachers

ERIC Educational Resources Information Center

Meydan, Ali

2017-01-01

As geography program has been discussed with the constructivist approach, it has become necessary to enhance the lessons with activities. Geography teachers implement the activities in course books, on the one hand, and also use the activities other teachers prepared or the activities in social network websites, on the other. However, what is more…

10 Myths & Realities about Community College Teacher Education Programs. Second Edition

ERIC Educational Resources Information Center

Maricopa Community Colleges, 2009

2009-01-01

As community colleges emerge as a solution to the teacher quality and shortage issue, the National Association of Community College Teacher Education Programs (NACCTEP) created this pamphlet in an attempt to dispel any misperceptions individuals may have about the community college role in teacher education. "10 Myths About Community College…

Effects of biology teachers' professional knowledge and cognitive activation on students' achievement

NASA Astrophysics Data System (ADS)

Förtsch, Christian; Werner, Sonja; von Kotzebue, Lena; Neuhaus, Birgit J.

2016-11-01

This study examined the effects of teachers' biology-specific dimensions of professional knowledge - pedagogical content knowledge (PCK) and content knowledge (CK) - and cognitively activating biology instruction, as a feature of instructional quality, on students' learning. The sample comprised 39 German secondary school teachers whose lessons on the topic neurobiology were videotaped twice. Teachers' instruction was coded with regard to cognitive activation using a rating manual. Multilevel path analysis results showed a positive significant effect of cognitive activation on students' learning and an indirect effect of teachers' PCK on students' learning mediated through cognitive activation. These findings highlight the importance of PCK in preservice biology teachers' education. Items of the rating manual may be used to provide exemplars of concrete teaching situations during university seminars for preservice teacher education or professional development initiatives for in-service teachers.

What Successful Science Teachers Do: 75 Research-Based Strategies

ERIC Educational Resources Information Center

Glasgow, Neal A.; Cheyne, Michele; Yerrick, Randy K.

2010-01-01

The experience and science expertise of these award-winning authors makes this easy-to-use guide a teacher's treasure trove. This latest edition to the popular What Successful Teachers Do series describes 75 research-based strategies and outlines best practices for inquiry-oriented science. Each strategy includes a brief description of the…

GREENHOUSE WORKER, TEACHERS COPY.

ERIC Educational Resources Information Center

FITTS, JAMES; JOHNSON, JOHNNY

DESIGNED FOR VOCATIONAL AGRICULTURE STUDENTS IN A COOPERATIVE PART-TIME TRAINING PROGRAM, THIS GUIDE WAS DEVELOPED BY TWO VOCATIONAL AGRICULTURE TEACHERS WITH INTEREST, TRAINING, AND EXPERIENCE IN HORTICULTURE AND WAS COORDINATED AND EDITED BY A SUBJECT MATTER SPECIALIST. INCLUDED ARE TEN UNITS, EACH DIVIDED INTO TOPICS. EACH TOPIC INCLUDES A…

First-Hand Participation: Illuminating Teachers' Self-Perceptions of Physical Activity Delivery

ERIC Educational Resources Information Center

Till, Jude; Ferkins, Lesley

2014-01-01

The study examines school-based physical activity in investigating teachers' perceptions of a physical activity-related professional development (PD) intervention in New Zealand primary schools. Eighteen semi-structured interviews with six teachers from two schools was the primary data collection method. Using a selected programme, teachers'…

Basic Automotive Responsibilities. Life Skills. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This teacher's guide is designed for use in presenting a four-unit course in basic automotive responsibilities that is part of a life skills series intended to help students become more self-sufficient in their personal and professional lives. The course's four instructional units cover these topics: purchasing a motor vehicle, maintaining a motor…

Teachers' Everyday Professional Development: Mapping Informal Learning Activities, Antecedents, and Learning Outcomes

ERIC Educational Resources Information Center

Kyndt, Eva; Gijbels, David; Grosemans, Ilke; Donche, Vincent

2016-01-01

Although a lot is known about teacher development by means of formal learning activities, research on teachers' everyday learning is limited. In the current systematic review, we analyzed 74 studies focusing on teachers' informal learning to identify teachers' learning activities, antecedents for informal learning, and learning outcomes. In…

Multimode drug inducible CRISPR/Cas9 devices for transcriptional activation and genome editing

PubMed Central

Lu, Jia; Zhao, Chen; Zhao, Yingze; Zhang, Jingfang; Zhang, Yue; Chen, Li; Han, Qiyuan; Ying, Yue; Peng, Shuai; Ai, Runna; Wang, Yu

2018-01-01

Abstract Precise investigation and manipulation of dynamic biological processes often requires molecular modulation in a controlled inducible manner. The clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR associated protein 9 (Cas9) has emerged as a versatile tool for targeted gene editing and transcriptional programming. Here, we designed and vigorously optimized a series of Hybrid drug Inducible CRISPR/Cas9 Technologies (HIT) for transcriptional activation by grafting a mutated human estrogen receptor (ERT2) to multiple CRISPR/Cas9 systems, which renders them 4-hydroxytamoxifen (4-OHT) inducible for the access of genome. Further, extra functionality of simultaneous genome editing was achieved with one device we named HIT2. Optimized terminal devices herein delivered advantageous performances in comparison with several existing designs. They exerted selective, titratable, rapid and reversible response to drug induction. In addition, these designs were successfully adapted to an orthogonal Cas9. HIT systems developed in this study can be applied for controlled modulation of potentially any genomic loci in multiple modes. PMID:29237052

Winds and Weather, Teacher's Edition. Probing the Natural World/3.

ERIC Educational Resources Information Center

Florida State Univ., Tallahassee. Dept. of Science Education.

The teacher's edtion for the Intermediate Science Curriculum Study Level III unit entitled "Winds and Weather" provides instructions for teachers for examining some principles underlying thermal convention, weather observation, closed systems, moisture and cloud formation, the heated-air model, and fronts. A brief introduction dealing…

Abundant off-target edits from site-directed RNA editing can be reduced by nuclear localization of the editing enzyme.

PubMed

Vallecillo-Viejo, Isabel C; Liscovitch-Brauer, Noa; Montiel-Gonzalez, Maria Fernanda; Eisenberg, Eli; Rosenthal, Joshua J C

2018-01-02

Site-directed RNA editing (SDRE) is a general strategy for making targeted base changes in RNA molecules. Although the approach is relatively new, several groups, including our own, have been working on its development. The basic strategy has been to couple the catalytic domain of an adenosine (A) to inosine (I) RNA editing enzyme to a guide RNA that is used for targeting. Although highly efficient on-target editing has been reported, off-target events have not been rigorously quantified. In this report we target premature termination codons (PTCs) in messages encoding both a fluorescent reporter protein and the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein transiently transfected into human epithelial cells. We demonstrate that while on-target editing is efficient, off-target editing is extensive, both within the targeted message and across the entire transcriptome of the transfected cells. By redirecting the editing enzymes from the cytoplasm to the nucleus, off-target editing is reduced without compromising the on-target editing efficiency. The addition of the E488Q mutation to the editing enzymes, a common strategy for increasing on-target editing efficiency, causes a tremendous increase in off-target editing. These results underscore the need to reduce promiscuity in current approaches to SDRE.

RNA editing with CRISPR-Cas13.

PubMed

Cox, David B T; Gootenberg, Jonathan S; Abudayyeh, Omar O; Franklin, Brian; Kellner, Max J; Joung, Julia; Zhang, Feng

2017-11-24

Nucleic acid editing holds promise for treating genetic disease, particularly at the RNA level, where disease-relevant sequences can be rescued to yield functional protein products. Type VI CRISPR-Cas systems contain the programmable single-effector RNA-guided ribonuclease Cas13. We profiled type VI systems in order to engineer a Cas13 ortholog capable of robust knockdown and demonstrated RNA editing by using catalytically inactive Cas13 (dCas13) to direct adenosine-to-inosine deaminase activity by ADAR2 (adenosine deaminase acting on RNA type 2) to transcripts in mammalian cells. This system, referred to as RNA Editing for Programmable A to I Replacement (REPAIR), which has no strict sequence constraints, can be used to edit full-length transcripts containing pathogenic mutations. We further engineered this system to create a high-specificity variant and minimized the system to facilitate viral delivery. REPAIR presents a promising RNA-editing platform with broad applicability for research, therapeutics, and biotechnology. Copyright © 2017, American Association for the Advancement of Science.

Probability & Statistics: Modular Learning Exercises. Teacher Edition

ERIC Educational Resources Information Center

Actuarial Foundation, 2012

2012-01-01

The purpose of these modules is to provide an introduction to the world of probability and statistics to accelerated mathematics students at the high school level. The modules also introduce students to real world math concepts and problems that property and casualty actuaries come across in their work. They are designed to be used by teachers and…

Busy Teachers: A Case of Comparing Online Teacher-Created Activities with the Ready-Made Activity Resource Books

ERIC Educational Resources Information Center

Khoshhal, Yasin

2016-01-01

With the ever-growing needs for more resources, the lack of concentration on preparing an exclusive activity for a particular classroom can be observed in a large number of educational contexts. The present study investigates the efficiency of ready-made activities for busy teachers. To this end, an activity from the ready-made resource book,…

Secondary School Teachers' Classroom Activities and Their Perceptions on Effectiveness of the Activity

ERIC Educational Resources Information Center

Guvenc, Hulya

2017-01-01

In the present research, effective and ineffective activities that secondary school teachers used and their perceptions on the effectiveness of the activities are investigated. The data were collected from 20 teachers using semi-structured interviews. Data were analysed using open coding and directed content analysis. Research findings showed that…

Power Product Equipment Technician: Outboard-Engine Boat Systems. Teacher Edition [and] Student Edition.

ERIC Educational Resources Information Center

Hilley, Robert

This curriculum guide contains teacher and student materials for a course on outboard-engine boat systems for power product equipment technician occupations. The course contains the following three units of instruction: (1) Orientation to Outboard-Engine Boat Systems and Rigging; (2) Trailers and Safe Towing and Boat Operation; and (3) Seasonal…

APOBEC3A cytidine deaminase induces RNA editing in monocytes and macrophages

PubMed Central

Sharma, Shraddha; Patnaik, Santosh K.; Thomas Taggart, R.; Kannisto, Eric D.; Enriquez, Sally M.; Gollnick, Paul; Baysal, Bora E.

2015-01-01

The extent, regulation and enzymatic basis of RNA editing by cytidine deamination are incompletely understood. Here we show that transcripts of hundreds of genes undergo site-specific C>U RNA editing in macrophages during M1 polarization and in monocytes in response to hypoxia and interferons. This editing alters the amino acid sequences for scores of proteins, including many that are involved in pathogenesis of viral diseases. APOBEC3A, which is known to deaminate cytidines of single-stranded DNA and to inhibit viruses and retrotransposons, mediates this RNA editing. Amino acid residues of APOBEC3A that are known to be required for its DNA deamination and anti-retrotransposition activities were also found to affect its RNA deamination activity. Our study demonstrates the cellular RNA editing activity of a member of the APOBEC3 family of innate restriction factors and expands the understanding of C>U RNA editing in mammals. PMID:25898173

Mathematics teachers' conceptions about modelling activities and its reflection on their beliefs about mathematics

NASA Astrophysics Data System (ADS)

Shahbari, Juhaina Awawdeh

2018-07-01

The current study examines whether the engagement of mathematics teachers in modelling activities and subsequent changes in their conceptions about these activities affect their beliefs about mathematics. The sample comprised 52 mathematics teachers working in small groups in four modelling activities. The data were collected from teachers' Reports about features of each activity, interviews and questionnaires on teachers' beliefs about mathematics. The findings indicated changes in teachers' conceptions about the modelling activities. Most teachers referred to the first activity as a mathematical problem but emphasized only the mathematical notions or the mathematical operations in the modelling process; changes in their conceptions were gradual. Most of the teachers referred to the fourth activity as a mathematical problem and emphasized features of the whole modelling process. The results of the interviews indicated that changes in the teachers' conceptions can be attributed to structure of the activities, group discussions, solution paths and elicited models. These changes about modelling activities were reflected in teachers' beliefs about mathematics. The quantitative findings indicated that the teachers developed more constructive beliefs about mathematics after engagement in the modelling activities and that the difference was significant, however there was no significant difference regarding changes in their traditional beliefs.

[Genome-editing: focus on the off-target effects].

PubMed

He, Xiubin; Gu, Feng

2017-10-25

Breakthroughs of genome-editing in recent years have paved the way to develop new therapeutic strategies. These genome-editing tools mainly include Zinc-finger nucleases (ZFNs), Transcription activator-like effector nucleases (TALENs), and clustered regulatory interspaced short palindromic repeat (CRISPR)/Cas-based RNA-guided DNA endonucleases. However, off-target effects are still the major issue in genome editing, and limit the application in gene therapy. Here, we summarized the cause and compared different detection methods of off-targets.

Primary Sources. Update: Teachers' Views on Common Core State Standards

ERIC Educational Resources Information Center

Scholastic Inc. and the Bill & Melinda Gates Foundation, 2014

2014-01-01

Scholastic and the Bill & Melinda Gates Foundation fielded the third edition of the "Primary Sources" survey of America's teachers in July 2013 (see ED562664). Twenty thousand pre-K through grade 12 public school teachers responded, sharing their perspectives on issues important to their profession, including the Common Core State…

Teacher Learning that Matters: International Perspectives. Routledge Research in Education

ERIC Educational Resources Information Center

Kooy, Mary, Ed.; van Veen, Klaas, Ed.

2011-01-01

In the continuing global call for educational reforms and change, the contributors in this edited collection address the critical issue of teacher learning from diverse national contexts and perspectives. They define "teacher learning that matters" as it shapes and directs pedagogical practices with the goal of improving student learning. Student…

Novice Teachers' Infusion into Pedagogical Activity at American Schools

ERIC Educational Resources Information Center

Chychuk, Antonina

2016-01-01

The article deals with innovations used in the USA to assist novice teachers with adaptation to professional activity. It has been found out that the experience in implementing support programs for novice teachers and introducing the position of a mentor at schools is an extremely innovative system of novice teachers' adaptation in the USA. The…

Reading Assessment: Principles and Practices for Elementary Teachers. Second Edition

ERIC Educational Resources Information Center

Barrentine, Shelby J., Ed.; Stokes, Sandra M., Ed.

2005-01-01

How do teachers respond to the competing pressures of school accountability, high-stakes testing, classroom assessment and instruction? This updated collection of articles from The Reading Teacher can help. Readers will find tools for: (1) Building school assessment policies; (2) Helping students succeed on high-stakes tests; (3) Using assessment…

Advances in targeted genome editing.

PubMed

Perez-Pinera, Pablo; Ousterout, David G; Gersbach, Charles A

2012-08-01

New technologies have recently emerged that enable targeted editing of genomes in diverse systems. This includes precise manipulation of gene sequences in their natural chromosomal context and addition of transgenes to specific genomic loci. This progress has been facilitated by advances in engineering targeted nucleases with programmable, site-specific DNA-binding domains, including zinc finger proteins and transcription activator-like effectors (TALEs). Recent improvements have enhanced nuclease performance, accelerated nuclease assembly, and lowered the cost of genome editing. These advances are driving new approaches to many areas of biotechnology, including biopharmaceutical production, agriculture, creation of transgenic organisms and cell lines, and studies of genome structure, regulation, and function. Genome editing is also being investigated in preclinical and clinical gene therapies for many diseases. Copyright © 2012 Elsevier Ltd. All rights reserved.

Wikipedia editing dynamics.

PubMed

Gandica, Y; Carvalho, J; Sampaio Dos Aidos, F

2015-01-01

A model for the probabilistic function followed in editing Wikipedia is presented and compared with simulations and real data. It is argued that the probability of editing is proportional to the editor's number of previous edits (preferential attachment), to the editor's fitness, and to an aging factor. Using these simple ingredients, it is possible to reproduce the results obtained for Wikipedia editing dynamics for a collection of single pages as well as the averaged results. Using a stochastic process framework, a recursive equation was obtained for the average of the number of edits per editor that seems to describe the editing behavior in Wikipedia.

Wikipedia editing dynamics

NASA Astrophysics Data System (ADS)

Gandica, Y.; Carvalho, J.; Sampaio dos Aidos, F.

2015-01-01

A model for the probabilistic function followed in editing Wikipedia is presented and compared with simulations and real data. It is argued that the probability of editing is proportional to the editor's number of previous edits (preferential attachment), to the editor's fitness, and to an aging factor. Using these simple ingredients, it is possible to reproduce the results obtained for Wikipedia editing dynamics for a collection of single pages as well as the averaged results. Using a stochastic process framework, a recursive equation was obtained for the average of the number of edits per editor that seems to describe the editing behavior in Wikipedia.

Microgravity: Teacher's Guide with Activities for Physical Science.

ERIC Educational Resources Information Center

Vogt, Gregory L.; Wargo, Michael J.

This teacher's guide to microgravity contains 16 student science activities with full background information to facilitate an understanding of the concepts of microgravity for teachers and students. Topics covered in the background sections include the definitions of gravity and microgravity, creating microgravity, the fluid state, combustion…

Genome editing comes of age.

PubMed

Kim, Jin-Soo

2016-09-01

Genome editing harnesses programmable nucleases to cut and paste genetic information in a targeted manner in living cells and organisms. Here, I review the development of programmable nucleases, including zinc finger nucleases (ZFNs), TAL (transcription-activator-like) effector nucleases (TALENs) and CRISPR (cluster of regularly interspaced palindromic repeats)-Cas9 (CRISPR-associated protein 9) RNA-guided endonucleases (RGENs). I specifically highlight the key advances that set the foundation for the rapid and widespread implementation of CRISPR-Cas9 genome editing approaches that has revolutionized the field.

The First-Year Teacher: Teaching with Confidence (K-8). New Revised Edition.

ERIC Educational Resources Information Center

Bosch, Karen A.; Kersey, Katharine C.

This book offers beginning teachers daily step-by-step plans for the first 4 weeks of school. It is based on a survey of first year teachers that examined their problems, concerns, needs, and feelings. It is also based on a task force of preservice and inservice teachers who set an agenda and tasks to find out more about beginning teacher needs.…

Dialogue for Change. Options for Re-Structuring K-12 Education. 3rd Edition, 1988.

ERIC Educational Resources Information Center

Metropolitan Affairs Corp., Detroit, MI.

This Third Edition of the 1985 report, "Dialogue for Change," discusses options and examples of educational choice and teacher empowerment and summarizes developments between 1985 and 1987. The following key options are discussed in Chapter 1, "Proposed Options for Change": (1) magnet schools; (2) open enrollment; (3) purchase…

A Celebration of Teachers for the Diamond Jubilee of the National Council of Teachers of English. New Edition.

ERIC Educational Resources Information Center

National Council of Teachers of English, Urbana, IL.

Recognition of teachers has been a focus of the Diamond Jubilee Year of the National Council of Teachers of English (1985-86), which honors the outstanding teachers of some of the nation's leaders in this collection of testimonials about the influence these teachers have had on their lives. Contributors to the collection are Margaret Walker…

The technical editing internship: What makes it work

DOE Office of Scientific and Technical Information (OSTI.GOV)

Caruthers, C.M.; Caruthers, L.E.; Schmidt, B.J.

1988-01-01

The following paper presents the experiences and perceptions of the three main participants of a technical editing internship at Argonne National Laboratory during the summer of 1986. Linda Caruthers, Clifford Caruthers, and Bryan Schmidt/emdash/teacher, supervisor, and intern, respectively/emdash/share what they received as their roles and responsibilities in guiding, managing, and becoming an entry-level technical editor. The following discussions demonstrate how the efforts of three people pursuing different objectives achieve the primary goal of all technical writers and editors: high-quality publications.

Critical Pedagogy for Rural Teachers?

ERIC Educational Resources Information Center

Theobald, Paul; Theobald, Jan

Three books represent the recent work of leading U.S. proponents of critical approaches to pedagogy: "Life in Schools: An Introduction to Critical Pedagogy in the Foundations of Education," by Peter McLaren; "Freire for the Classroom: A Sourcebook for Liberatory Teaching," edited by Ira Shor; and "Teachers as…

Student, teacher, and classroom predictors of between-teacher variance of students' teacher-rated behavior.

PubMed

Splett, Joni W; Smith-Millman, Marissa; Raborn, Anthony; Brann, Kristy L; Flaspohler, Paul D; Maras, Melissa A

2018-03-08

The current study examined between-teacher variance in teacher ratings of student behavioral and emotional risk to identify student, teacher and classroom characteristics that predict such differences and can be considered in future research and practice. Data were taken from seven elementary schools in one school district implementing universal screening, including 1,241 students rated by 68 teachers. Students were mostly African America (68.5%) with equal gender (female 50.1%) and grade-level distributions. Teachers, mostly White (76.5%) and female (89.7%), completed both a background survey regarding their professional experiences and demographic characteristics and the Behavior Assessment System for Children (Second Edition) Behavioral and Emotional Screening System-Teacher Form for all students in their class, rating an average of 17.69 students each. Extant student data were provided by the district. Analyses followed multilevel linear model stepwise model-building procedures. We detected a significant amount of variance in teachers' ratings of students' behavioral and emotional risk at both student and teacher/classroom levels with student predictors explaining about 39% of student-level variance and teacher/classroom predictors explaining about 20% of between-teacher differences. The final model fit the data (Akaike information criterion = 8,687.709; pseudo-R2 = 0.544) significantly better than the null model (Akaike information criterion = 9,457.160). Significant predictors included student gender, race ethnicity, academic performance and disciplinary incidents, teacher gender, student-teacher gender interaction, teacher professional development in behavior screening, and classroom academic performance. Future research and practice should interpret teacher-rated universal screening of students' behavioral and emotional risk with consideration of the between-teacher variance unrelated to student behavior detected. (PsycINFO Database Record (c) 2018 APA, all

Gender Balance Analysis of the Metropolitan Achievement Tests, 1978 Edition.

ERIC Educational Resources Information Center

Jensen, Marjane; Beck, Michael D.

The 1978 edition of the Metropolitan Achievement Tests was analyzed for sex stereotyping and for the use of male, female, or neuter references and a comparison was made with the 1970 edition. There was less bias in the new edition, and there was relatively little sex stereotyping with respect to occupations, activities, and roles for females.…

Visual Messages: Integrating Imagery into Instruction. A Media Literacy Resource for Teachers. Second Edition.

ERIC Educational Resources Information Center

Considine, David M.; Haley, Gail E.

Connecting the curriculum of the K-12 classroom with the "curriculum of the living room," this book helps teachers and library media specialists maintain a viable program of visual (or media) literacy by presenting background information on the visual literacy movement and dozens of effective strategies and classroom activities that are ready to…

Teachers' Goal Orientation Profiles and Participation in Professional Development Activities

ERIC Educational Resources Information Center

Kunst, Eva M.; van Woerkom, Marianne; Poell, Rob F.

2018-01-01

Participation in professional development activities is important for teachers to continuously improve their knowledge and skills. However, teachers differ in their attitude towards learning activities. This paper examined how different goal orientation profiles are related to participation in professional development activities (acquiring…

Really Writing! Ready-To-Use Writing Process Activities for the Elementary Grades. 2nd Edition

ERIC Educational Resources Information Center

Sunflower, Cherlyn

2005-01-01

The second edition of "Really Writing!" provides 40 real-life writing activities designed to capture the attention of young authors (grades 2 through 6) who are just learning the composing process. This book is also a resource for teaching advanced writers who are ready to experiment with a variety of writing and speaking genres. Each of the…

STEM Outreach Activities: An Approach to Teachers' Professional Development

ERIC Educational Resources Information Center

Aslam, Farzana; Adefila, Arinola; Bagiya, Yamuna

2018-01-01

STEM outreach programmes in secondary schools are mediated by STEM teachers who are responsible for organising, implementing and evaluating the activities with a view to promoting STEM subjects. However, research investigating teachers' STEM roles and professional development through participation in outreach activities is limited. This paper…

Teacher Activism: Enacting a Vision for Social Justice

ERIC Educational Resources Information Center

Picower, Bree

2012-01-01

This qualitative study focused on educators who participated in grassroots social justice groups to explore the role teacher activism can play in the struggle for educational justice. Findings show teacher activists made three overarching commitments: to reconcile their vision for justice with the realities of injustice around them; to work within…

Factors Influencing Teachers' Engagement in Informal Learning Activities

ERIC Educational Resources Information Center

Lohman, Margaret C.

2006-01-01

Purpose: The purpose of this study is to examine factors influencing the engagement of public school teachers in informal learning activities. Design/methodology/approach: This study used a survey research design. Findings: Analysis of the data found that teachers rely to a greater degree on interactive than on independent informal learning…

The Art of Problem Posing. 3rd Edition

ERIC Educational Resources Information Center

Brown, Stephen I.; Walter, Marion I.

2005-01-01

The new edition of this classic book describes and provides a myriad of examples of the relationships between problem posing and problem solving, and explores the educational potential of integrating these two activities in classrooms at all levels. "The Art of Problem Posing, Third Edition" encourages readers to shift their thinking…

Ideas Para Fortalecer Las Destrezas en Matematicas. Ideas for Strengthening Mathematics Skills. Spanish Edition.

ERIC Educational Resources Information Center

New York State Education Dept., Albany. Bureau of Bilingual Education.

Presented is an overview of some specific schemes that have been used successfully by teachers throughout New York State to strengthen basic mathematics skills. Components offer ideas that have been successful with primary, intermediate, and secondary students. The contents of this Spanish language edition are identical to the English language and…

Idee Per Consolidare Le Abilita In Matematica. Ideas for Strengthening Mathematics Skills. Italian Edition.

ERIC Educational Resources Information Center

New York State Education Dept., Albany. Bureau of Bilingual Education.

Presented is an overview of some specific schemes that have been used successfully by teachers throughout New York State to strengthen basic mathematics skills. Components offer ideas that have been successful with primary, intermediate, and secondary students. The contents of this Italian language edition are identical to the English language and…

Sounds Like Fun: Activities for Developing Phonological Awareness, Revised Edition

ERIC Educational Resources Information Center

Spector, Cecile Cyrul

2009-01-01

Kids love jokes--and teachers and SLPs love fast and easy ways to improve students' phonological awareness. That's why every elementary and middle-school SLP and educator needs this playful, effective activity book, packed with jokes and riddles that increase students' awareness of the phonemes that make up words. The perfect way to avoid "drill…

The Mathematics Education of Elementary Teachers: Issues and Strategies for Content Courses

ERIC Educational Resources Information Center

Hart, Lynn C., Ed.; Oesterle, Susan, Ed.; Auslander, Susan Swars, Ed.; Kajander, Ann, Ed.

2016-01-01

This book is an edited volume addressing specific issues of significance for individuals involved with the undergraduate mathematics content preparation of prospective elementary teachers (PSTs). Teaching mathematics content courses to this group of students presents unique challenges. While some PSTs enter their teacher preparation with weak…

Attention Science Teachers: Classroom Activities with Water.

ERIC Educational Resources Information Center

HAZWRAP, The Hazardous Waste Remedial Actions Program.

This collection of 10 activities is designed to give students a better grasp of concepts relating to groundwater, aquifers, and hydrology. Activities can be conducted as a demonstration (especially for younger students) or as a laboratory activity for students in higher grades. The guide contains an introduction for teachers and students, a…

Genetic spell-checking: gene editing using single-stranded DNA oligonucleotides.

PubMed

Rivera-Torres, Natalia; Kmiec, Eric B

2016-02-01

Single-stranded oligonucleotides (ssODNs) can be used to direct the exchange of a single nucleotide or the repair of a single base within the coding region of a gene in a process that is known, generically, as gene editing. These molecules are composed of either all DNA residues or a mixture of RNA and DNA bases and utilize inherent metabolic functions to execute the genetic alteration within the context of a chromosome. The mechanism of action of gene editing is now being elucidated as well as an understanding of its regulatory circuitry, work that has been particularly important in establishing a foundation for designing effective gene editing strategies in plants. Double-strand DNA breakage and the activation of the DNA damage response pathway play key roles in determining the frequency with which gene editing activity takes place. Cellular regulators respond to such damage and their action impacts the success or failure of a particular nucleotide exchange reaction. A consequence of such activation is the natural slowing of replication fork progression, which naturally creates a more open chromatin configuration, thereby increasing access of the oligonucleotide to the DNA template. Herein, how critical reaction parameters influence the effectiveness of gene editing is discussed. Functional interrelationships between DNA damage, the activation of DNA response pathways and the stalling of replication forks are presented in detail as potential targets for increasing the frequency of gene editing by ssODNs in plants and plant cells. © 2015 Society for Experimental Biology, Association of Applied Biologists and John Wiley & Sons Ltd.

Kindergarten Teachers' Orchestration of Mathematical Activities Afforded by Technology: Agency and Mediation

ERIC Educational Resources Information Center

Carlsen, Martin; Erfjord, Ingvald; Hundeland, Per Sigurd; Monaghan, John

2016-01-01

This paper focuses on kindergarten teachers' interactions with young children during mathematical learning activities involving the use of digital tools. We aim to characterise the teachers' roles and actions in these activities and extend considerations of teachers' orchestrations current in the research literature with regard to agency and…

Teachers' Purposeful Design of Effective Technology Learning Activities

ERIC Educational Resources Information Center

Morgan, John Andrew Kerlin

2014-01-01

The goal of this study was to explore how exemplary teachers design learning activities that incorporate the use of technology. Teachers at three schools in a school district in Southern California were solicited for a survey regarding their use of technology in the classroom. Based on the surveys, high and low technology implementers were…

Robotics-Control Technology. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This document contains the materials required for presenting an 8-day competency-based technology learning activity (TLA) designed to introduce students in grades 6-10 to advances and career opportunities in the field of robotics-control technology. The guide uses hands-on exploratory experiences into which activities to help students develop…

Teaching Science in Elementary and Middle School: A Cognitive and Cultural Approach. Second Edition

ERIC Educational Resources Information Center

Buxton, Cory A.; Provenzo, Eugene F., Jr.

2010-01-01

Featuring an increased emphasis on the way today's changing science and technology is shaping our culture, this Second Edition of "Teaching Science in Elementary and Middle School" provides pre- and in-service teachers with an introduction to basic science concepts and methods of science instruction, as well as practical strategies for the…

Oral health activities of early head start teachers directed toward children and parents.

PubMed

Kranz, Ashley M; Rozier, R Gary; Zeldin, Leslie P; Preisser, John S

2011-01-01

This cross-sectional study examined Early Head Start (EHS) teachers' oral health program activities and their association with teacher and program characteristics. Self-completed questionnaires were distributed to the staff in all EHS programs in North Carolina. Variables for dental health activities for parents (four items) and children (four items) were constructed as the sum of responses to a 0-4 Likert-type scale (never to very frequently). Ordinary least squares regression models examined the association between teachers' oral health program activities and modifiable teacher (oral health knowledge, values, self-efficacy, dental health training, perceived barriers to dental activities) and program (director and health coordinator knowledge and perceived barriers to dental activities) characteristics. Teachers in the parent (n=260) and child (n=231) analyses were a subset of the 485 staff respondents (98 percent response rate). Teachers engaged in child oral health activities (range = 0-16; mean = 9.0) more frequently than parent activities (range = 0-16; mean = 6.9). Teachers' oral health values, perceived oral health self-efficacy, dental training, and director and health coordinator knowledge were positively associated with oral health activities (P < 0.05). Perceived barriers were negatively associated with child activities (P < 0.05). The level of oral health activity in EHS programs is less than optimal. Several characteristics of EHS staff were identified that can be targeted with education interventions. Evidence for effectiveness of EHS interventions needs to be strengthened, but results of this survey provide encouraging findings about the potential effects of teacher training on their oral health practices.

Pedagogical and Social Climate in School Questionnaire: Factorial Validity and Reliability of the Teacher Version

ERIC Educational Resources Information Center

Dimitrova, Radosveta; Ferrer-Wreder, Laura; Galanti, Maria Rosaria

2016-01-01

This study evaluated the factorial structure of the Pedagogical and Social Climate in School (PESOC) questionnaire among 307 teachers in Bulgaria. The teacher edition of PESOC consists of 11 scales (i.e., Expectations for Students, Unity Among Teachers, Approach to Students, Basic Assumptions About Students' Ability to Learn, School-Home…

Teachers as Writers: Who Me?

ERIC Educational Resources Information Center

Way, Jenni

2004-01-01

In an earlier edition of this journal, Paul Swan (1997) published an article called "Writing for journals: An avenue for professional development". His article encourages teachers to share their experiences and ideas by becoming writers of APMC journal articles, and in doing so, engage in professional development. The set of guidelines Swan…

Teacher Use of Creativity-Enhancing Activities in Chinese and American Elementary Classrooms

ERIC Educational Resources Information Center

Hartley, Kylie A.; Plucker, Jonathan A.

2014-01-01

The purpose of these exploratory studies was to examine Chinese and American elementary teachers' perceptions of how various classroom activities contribute to student creativity, and how often teachers report engaging their students in these activities. Third, fourth, and fifth grade teachers in the Midwestern United States (N = 51) and in…

Solar Energy Education. Humanities: activities and teacher's guide. Field test edition

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1982-01-01

Activities are outlined to introduce students to information on solar energy while performing ordinary classroom work. In this teaching manual solar energy is integrated with the humanities. The activities include such things as stories, newspapers, writing assignments, and art and musical presentations all filled with energy related terms. An energy glossary is provided. (BCS)

Thermal Screen Printing. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum guide provides technology learning activities designed to prepare students in grades 6-10 to work in the world of the future. The 8-day course provides exploratory, hands-on learning activities and information that can enhance the education of students of all types in an integrated curriculum that provides practical applications of…

Research and Design. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum guide provides technology learning activities designed to prepare students in grades 6-10 to work in the world of the future. The 8-day course provides exploratory, hands-on learning activities and information that can enhance the education of students of all types in an integrated curriculum that provides practical applications of…

Mediated Plastid RNA Editing in Plant Immunity

PubMed Central

García-Andrade, Javier; Ramírez, Vicente; López, Ana; Vera, Pablo

2013-01-01

Plant regulatory circuits coordinating nuclear and plastid gene expression have evolved in response to external stimuli. RNA editing is one of such control mechanisms. We determined the Arabidopsis nuclear-encoded homeodomain-containing protein OCP3 is incorporated into the chloroplast, and contributes to control over the extent of ndhB transcript editing. ndhB encodes the B subunit of the chloroplast NADH dehydrogenase-like complex (NDH) involved in cyclic electron flow (CEF) around photosystem I. In ocp3 mutant strains, ndhB editing efficiency decays, CEF is impaired and disease resistance to fungal pathogens substantially enhanced, a process recapitulated in plants defective in editing plastid RNAs encoding NDH complex subunits due to mutations in previously described nuclear-encoded pentatricopeptide-related proteins (i.e. CRR21, CRR2). Furthermore, we observed that following a pathogenic challenge, wild type plants respond with editing inhibition of ndhB transcript. In parallel, rapid destabilization of the plastidial NDH complex is also observed in the plant following perception of a pathogenic cue. Therefore, NDH complex activity and plant immunity appear as interlinked processes. PMID:24204264

Professional Learning Activities in Context: A Statewide Survey of Middle School Mathematics Teachers

ERIC Educational Resources Information Center

Akiba, Motoko

2012-01-01

Based on a statewide survey of professional learning activities among 577 middle school mathematics teachers in Missouri, this study examined two questions: 1) What professional learning activities do middle school math teachers participate in and how much time do they spend in these activities?, and 2) How are teacher qualifications and…

Audiovisual Programming. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on audiovisual programming for students in grades 6-10 consists of a technology education overview, information on use, and the instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections…

Health Occupations. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on health occupations for students in grades 6-10 consists of a technology education overview, information on use, and instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections are…

Electronic Publishing. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on electronic publishing for students in grades 6-10 consists of a technology education overview, information on use, and the instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor and student sections are…

Career Search. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on career search for students in grades 6-10 consists of a technology education overview, information on use, and the instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections are…

African Studies Curriculum Materials for Teachers. Second Edition.

ERIC Educational Resources Information Center

Illinois Univ., Urbana. Center for African Studies.

This handbook features an exhaustive collection of African studies curriculum materials considered most appropriate for teachers. The material is coded for elementary school, middle school, senior high school/adult, and general interest. Material is presented in the following chapters: "General Information" which contains facts sheets on…

Impact of Technology on the Family. Teacher Edition.

ERIC Educational Resources Information Center

Mid-America Vocational Curriculum Consortium, Stillwater, OK.

These instructional materials create an awareness of new technological innovations and how they affect personal and family life. This teacher's guide is for instructing secondary students enrolled in a home economics program. The following introductory information is included: use of this publication, competency profile, instructional/task…

Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing

PubMed Central

Lee, Ciaran M; Cradick, Thomas J; Fine, Eli J; Bao, Gang

2016-01-01

The rapid advancement in targeted genome editing using engineered nucleases such as ZFNs, TALENs, and CRISPR/Cas9 systems has resulted in a suite of powerful methods that allows researchers to target any genomic locus of interest. A complementary set of design tools has been developed to aid researchers with nuclease design, target site selection, and experimental validation. Here, we review the various tools available for target selection in designing engineered nucleases, and for quantifying nuclease activity and specificity, including web-based search tools and experimental methods. We also elucidate challenges in target selection, especially in predicting off-target effects, and discuss future directions in precision genome editing and its applications. PMID:26750397

Examining of Model Eliciting Activities Developed by Mathematics Student Teachers

ERIC Educational Resources Information Center

Dede, Ayse Tekin; Hidiroglu, Çaglar Naci; Güzel, Esra Bukova

2017-01-01

The purpose of this study is to examine the model eliciting activities developed by the mathematics student teachers in the context of the principles of the model eliciting activities. The participants of the study conducted as a case study design were twenty one mathematics student teachers working on seven groups. The data collection tools were…

Teacher Feedback during Active Learning: Current Practices in Primary Schools

ERIC Educational Resources Information Center

van den Bergh, Linda; Ros, Anje; Beijaard, Douwe

2013-01-01

Background: Feedback is one of the most powerful tools, which teachers can use to enhance student learning. It appears dif?cult for teachers to give qualitatively good feedback, especially during active learning. In this context, teachers should provide facilitative feedback that is focused on the development of meta-cognition and social learning.…

Introduction to Natural Resources. Third Edition. Teacher Edition [and] Student Guide [and] Student Workbook.

ERIC Educational Resources Information Center

Hehn, Darold; Newport, Bob

These student and teacher guides are designed for a secondary-level course in natural resources that focuses on renewable and nonrenewable natural resources, methods of protecting the environment, and the various careers and technologies available in the natural resources area. The following topics are covered in the course's 10 units: outdoor…

Power Product Equipment Technician: Outboard-Engine Systems and Service. Teacher Edition [and] Student Edition.

ERIC Educational Resources Information Center

Hilley, Robert

This curriculum guide contains teacher and student materials for a course on outboard-engine boat systems and service for power product equipment technician occupations. The course contains the following four units of instruction: (1) Outboard-Engine Design and Identification; (2) Operation and Service of Engine-Support Systems; (3) Operation and…

Agriculture Education SimFarm(TM). Technology Learning Activity. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This Technology Learning Activity (TLA) for agriculture education in grades 6-10 is designed to help students learn the basic terminology of a farm system while they experience the responsibility of keeping a profitable farm in operation through use of the interactive SimFarm software. Introductory materials provide an overview of technology…

Criminal Justice in America. Teacher's Guide. Second Edition.

ERIC Educational Resources Information Center

Croddy, Marshall; Hayes, Bill

This teacher's guide outlines effective strategies for using "Criminal Justice in America." This comprehensive textbook on criminal justice may serve either as the foundation for a high school law-related education course or as a supplemental text for civics, government or contemporary-issues courses. Designed to foster critical thinking…

Temperature effect on CRISPR-Cas9 mediated genome editing.

PubMed

Xiang, Guanghai; Zhang, Xingying; An, Chenrui; Cheng, Chen; Wang, Haoyi

2017-04-20

Zinc-finger nuclease (ZFN), transcription activator-like effector nuclease (TALEN), and clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR-Cas9) are the most commonly used genome editing tools. Previous studies demonstrated that hypothermia treatment increased the mutation rates induced by ZFNs and TALENs in mammalian cells. Here, we characterize the effect of different culture temperatures on CRISPR-Cas9 mediated genome editing and find that the genome editing efficiency of CRISPR-Cas9 is significantly hampered by hypothermia treatment, unlike ZFN and TALEN. In addition, hyperthermia culture condition enhances genome editing by CRISPR-Cas9 in some cell lines, due to the higher enzyme activity and sgRNA expression level at higher temperature. Our study has implications on CRISPR-Cas9 applications in a broad spectrum of species, many of which do not live at 37°C. Copyright © 2017 Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, and Genetics Society of China. Published by Elsevier Ltd. All rights reserved.

Examination of Pre-Service Science Teachers' Activities Using Problem Based Learning Method

ERIC Educational Resources Information Center

Ekici, Didem Inel

2016-01-01

In this study, both the activities prepared by pre-service science teachers regarding the Problem Based Learning method and the pre-service science teachers' views regarding the method were examined before and after applying their activities in a real class environment. 69 pre-service science teachers studying in the 4th grade of the science…

Genome editing systems in novel therapies.

PubMed

Jang, Yoon-Young; Cai, Liuhong; Ye, Zhaohui

2016-01-01

Genome editing is the process in which DNA sequences at precise genomic locations are modified. In the past three decades, genome editing by homologous recombination has been successfully performed in mouse for generating genetic models. The low efficiency of this process in human cells, however, had prevented its clinical application until the recent advancements in designer endonuclease technologies. The significantly improved genome editing efficiencies aided by ZFN, TALEN, and CRISPR systems provide unprecedented opportunities not only for biomedical research, but also for developing novel therapies. Applications based on these genome editing tools to disrupt deleterious genes, correct genetic mutations, deliver functional transgenes more effectively or even modify the epigenetic landscape are being actively investigated for gene and cell therapy purposes. Encouraging results have been obtained in limited clinical trials in the past two years. While most of the applications are still in proof-of-principle or preclinical development stages, it is anticipated that the coming years will see increasing clinical success in novel therapies based on the modern genome editing technologies. It should be noted that critical issues still remain before the technologies can be translated into more reliable therapies. These key issues include off-target evaluation, establishing appropriate preclinical models and improving the currently low efficiency of homology-based precise gene replacement. In this review we discuss the preclinical and clinical studies aiming at translating the genome editing technologies as well as the issues that are important for more successful translation.

The Law and the Teacher in Missouri--A Handbook for Teachers, Administrators, and School Board Members. Third Edition.

ERIC Educational Resources Information Center

Garber, Lee O.; Delon, Floyd G.

This book is designed to acquaint Missouri teachers with the state laws that affect them. Teachers' legal status, their rights, duties, and obligations are defined. Examples are taken from constitutional provisions, judicial decisions, and statutory enactments to show both general aspects of school law for all teachers and specific applications to…

Diesel Technology: Safety Skills. [Teacher and Student Editions.

ERIC Educational Resources Information Center

Kellum, Mary

Competency-based teacher and student materials are provided for three units on safety skills as part of a diesel technology curriculum. The units cover the following topics: general safety; workplace safety; and first aid. The materials are based on the curriculum-alignment concept of first stating the objectives, then developing instructional…

Science on TeacherTube: A Mixed Methods Analysis of Teacher Produced Video

NASA Astrophysics Data System (ADS)

Chmiel, Margaret (Marjee)

Increased bandwidth, inexpensive video cameras and easy-to-use video editing software have made social media sites featuring user generated video (UGV) an increasingly popular vehicle for online communication. As such, UGV have come to play a role in education, both formal and informal, but there has been little research on this topic in scholarly literature. In this mixed-methods study, a content and discourse analysis are used to describe the most successful UGV in the science channel of an education-focused site called TeacherTube. The analysis finds that state achievement tests, and their focus on vocabulary and recall-level knowledge, drive much of the content found on TeacherTube.

Genome Editing for the Study of Cardiovascular Diseases.

PubMed

Chadwick, Alexandra C; Musunuru, Kiran

2017-03-01

The opportunities afforded through the recent advent of genome-editing technologies have allowed investigators to more easily study a number of diseases. The advantages and limitations of the most prominent genome-editing technologies are described in this review, along with potential applications specifically focused on cardiovascular diseases. The recent genome-editing tools using programmable nucleases, such as zinc-finger nucleases, transcription activator-like effector nucleases, and clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (Cas9), have rapidly been adapted to manipulate genes in a variety of cellular and animal models. A number of recent cardiovascular disease-related publications report cases in which specific mutations are introduced into disease models for functional characterization and for testing of therapeutic strategies. Recent advances in genome-editing technologies offer new approaches to understand and treat diseases. Here, we discuss genome editing strategies to easily characterize naturally occurring mutations and offer strategies with potential clinical relevance.

Genome Editing for the Study of Cardiovascular Diseases

PubMed Central

Chadwick, Alexandra C.

2018-01-01

Purpose of Review The opportunities afforded through the recent advent of genome-editing technologies have allowed investigators to more easily study a number of diseases. The advantages and limitations of the most prominent genome-editing technologies are described in this review, along with potential applications specifically focused on cardiovascular diseases. Recent Findings The recent genome-editing tools using programmable nucleases, such as zinc-finger nucleases, transcription activator-like effector nucleases, and clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (Cas9), have rapidly been adapted to manipulate genes in a variety of cellular and animal models. A number of recent cardiovascular disease-related publications report cases in which specific mutations are introduced into disease models for functional characterization and for testing of therapeutic strategies. Summary Recent advances in genome-editing technologies offer new approaches to understand and treat diseases. Here, we discuss genome editing strategies to easily characterize naturally occurring mutations and offer strategies with potential clinical relevance. PMID:28220462

Foreign Language Teaching in Rudolf Steiner Schools. Guidelines for Class-Teachers and Language Teachers. First Edition.

ERIC Educational Resources Information Center

Stott, Michael

This book is intended for foreign language teachers interested in the approaches used in Rudolf Steiner schools, and also classroom teachers who teach foreign languages. Chapters address these issues: what the language lesson is to achieve; how the language lesson differs from other lessons; lesson design; examples of actual lessons; avoiding the…

Genome-Wide Analysis of A-to-I RNA Editing.

PubMed

Savva, Yiannis A; Laurent, Georges St; Reenan, Robert A

2016-01-01

Adenosine (A)-to-inosine (I) RNA editing is a fundamental posttranscriptional modification that ensures the deamination of A-to-I in double-stranded (ds) RNA molecules. Intriguingly, the A-to-I RNA editing system is particularly active in the nervous system of higher eukaryotes, altering a plethora of noncoding and coding sequences. Abnormal RNA editing is highly associated with many neurological phenotypes and neurodevelopmental disorders. However, the molecular mechanisms underlying RNA editing-mediated pathogenesis still remain enigmatic and have attracted increasing attention from researchers. Over the last decade, methods available to perform genome-wide transcriptome analysis, have evolved rapidly. Within the RNA editing field researchers have adopted next-generation sequencing technologies to identify RNA-editing sites within genomes and to elucidate the underlying process. However, technical challenges associated with editing site discovery have hindered efforts to uncover comprehensive editing site datasets, resulting in the general perception that the collections of annotated editing sites represent only a small minority of the total number of sites in a given organism, tissue, or cell type of interest. Additionally to doubts about sensitivity, existing RNA-editing site lists often contain high percentages of false positives, leading to uncertainty about their validity and usefulness in downstream studies. An accurate investigation of A-to-I editing requires properly validated datasets of editing sites with demonstrated and transparent levels of sensitivity and specificity. Here, we describe a high signal-to-noise method for RNA-editing site detection using single-molecule sequencing (SMS). With this method, authentic RNA-editing sites may be differentiated from artifacts. Machine learning approaches provide a procedure to improve upon and experimentally validate sequencing outcomes through use of computationally predicted, iterative feedback loops

Secondary science teachers' use of laboratory activities: Linking epistemological beliefs, goals, and practices

NASA Astrophysics Data System (ADS)

Kang, Nam-Hwa; Wallace, Carolyn S.

2005-01-01

The purpose of this study was to explore how science teachers' epistemological beliefs and teaching goals are related to their use of lab activities. Research questions include (a) What are the teachers' epistemological beliefs pertaining to lab activities? (b) Why do the science teachers use lab activities? (c) How are the teachers' epistemological beliefs and instructional goals related to teaching actions? Two major aspects of epistemologies guided this study: ontological aspect (certainty/diversity of truth) and relational aspect (relationship between the knower and the known). The ontological aspect addresses whether one views knowledge as one certain truth or as tentative multiple truths. The relational aspect addresses whether one views him/herself as a receiver of prescribed knowledge separating self from knowledge construction or as an active meaning maker connecting self to the knowledge construction processes. More sophisticated epistemological beliefs include the acknowledgement of multiple interpretations of the same phenomena and active role of the knower in knowledge construction. Three experienced secondary science teachers were interviewed and observed throughout an academic course. The findings illustrate that a teacher's naïve epistemological beliefs are clearly reflected in the teacher's teaching practices. However, a teacher's sophisticated epistemological beliefs are not always clearly connected to the practice. This seems to be related to the necessary negotiation among their epistemological beliefs, teaching contexts, and instructional goals. Ontological and relational beliefs seem to be connected to different facets of teaching practices. Findings indicate that various syntheses of different aspects of epistemological beliefs and instructional goals are linked to teachers' diverse ways of using lab activities. Implications for research and teacher education are discussed.

The Market System: Does It Work? Teacher's Edition.

ERIC Educational Resources Information Center

O'Neill, James B.

This document is the teacher's guide for SO 008 864. Developed for secondary students, the materials aid students in the understanding of the United States economic system. Along with the narrative found in the student materials, the guide presents objectives, concepts, procedures, and evaluation for completing the unit. The materials are arranged…

Teaching for Understanding: What It Is and How to Do It. 2nd Edition

ERIC Educational Resources Information Center

Newton, Douglas P.

2011-01-01

At a time when league tables can be everything, examination grades matter. Perhaps more than many would admit, the cost is a lack of understanding. The new edition of this book provides practical advice about how to support understanding in both children and adults. It is for all teachers and lecturers, experienced or otherwise, who want learners…

A robust TALENs system for highly efficient mammalian genome editing.

PubMed

Feng, Yuanxi; Zhang, Siliang; Huang, Xin

2014-01-10

Recently, transcription activator-like effector nucleases (TALENs) have emerged as a highly effective tool for genomic editing. A pair of TALENs binds to two DNA recognition sites separated by a spacer sequence, and the dimerized FokI nucleases at the C terminal then cleave DNA in the spacer. Because of its modular design and capacity to precisely target almost any desired genomic locus, TALEN is a technology that can revolutionize the entire biomedical research field. Currently, for genomic editing in cultured cells, two plasmids encoding a pair of TALENs are co-transfected, followed by limited dilution to isolate cell colonies with the intended genomic manipulation. However, uncertain transfection efficiency becomes a bottleneck, especially in hard-to-transfect cells, reducing the overall efficiency of genome editing. We have developed a robust TALENs system in which each TALEN plasmid also encodes a fluorescence protein. Thus, cells transfected with both TALEN plasmids, a prerequisite for genomic editing, can be isolated by fluorescence-activated cell sorting. Our improved TALENs system can be applied to all cultured cells to achieve highly efficient genomic editing. Furthermore, an optimized procedure for genomic editing using TALENs is also presented. We expect our system to be widely adopted by the scientific community.

Learning To Teach Science: Activities for Student Teachers and Mentors.

ERIC Educational Resources Information Center

Monk, Martin, Ed.; Dillon, Justin, Ed.

Despite the variations in the spontaneous ability of new teachers, teaching is both an art and a craft that can be learned through hard work and that demands close attention to detail. The practical purpose of this book is to provide mentors in England with activities to be used with their student teachers and to provide guidance on activities to…

Teacher Negotiations and Solutions to Impasse.

ERIC Educational Resources Information Center

Rollins, Sidney P., Ed.

This document contains edited presentations given during a conference on teacher negotiations and solutions to impasse in Rhode Island. The principal speakers were Henry J. Nardone, chairman of the Elementary and Secondary Education Sub-Committee of the Board of Regents; Julius C. Michaelson, Attorney General for Rhode Island; and Dr. Peter…

Forestry. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum is designed to provide training in skills used by technicians and foresters throughout the world who plant, care for, and harvest trees. It contains 16 units. Each instructional unit includes some or all of the basic components of a unit of instruction: performance objectives, suggested activities, handouts, information sheets,…

Creating Futures Activity Cards and Teacher Guide.

ERIC Educational Resources Information Center

Klenzman, Elizabeth; Taylor, Paula

Teachers can use these learning activities to teach about the future in elementary and secondary social studies, science, math, language arts, and arts courses. The purpose of the activities is to help students practice creative-thinking skills, investigate problems relevant to their personal futures, experience the concept of change, and evaluate…

Introduction to Agricultural Products and Processing. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This document consists of the teacher's guide to a module designed to teach high school students entry-level job competencies in the new areas of agriculture that are now emerging. The module, one of a series of publications designed to identify these new competencies, contains 11 instructional units that cover the following topics: trends in…

The Newbery and Caldecott Awards: A Guide to the Medal and Honor Books. 2012 Edition

ERIC Educational Resources Information Center

ALA Editions, 2012

2012-01-01

Updated to include the 2012 award and honor books, this new edition of the annual guide to the Newbery and Caldecott awards gathers together the books deemed most distinguished in American children's literature and illustration since the inception of the renowned prizes. Librarians and teachers everywhere rely on this guidebook for quick reference…

C-to-U editing and site-directed RNA editing for the correction of genetic mutations.

PubMed

Vu, Luyen Thi; Tsukahara, Toshifumi

2017-07-24

Cytidine to uridine (C-to-U) editing is one type of substitutional RNA editing. It occurs in both mammals and plants. The molecular mechanism of C-to-U editing involves the hydrolytic deamination of a cytosine to a uracil base. C-to-U editing is mediated by RNA-specific cytidine deaminases and several complementation factors, which have not been completely identified. Here, we review recent findings related to the regulation and enzymatic basis of C-to-U RNA editing. More importantly, when C-to-U editing occurs in coding regions, it has the power to reprogram genetic information on the RNA level, therefore it has great potential for applications in transcript repair (diseases related to thymidine to cytidine (T>C) or adenosine to guanosine (A>G) point mutations). If it is possible to manipulate or mimic C-to-U editing, T>C or A>G genetic mutation-related diseases could be treated. Enzymatic and non-enzymatic site-directed RNA editing are two different approaches for mimicking C-to-U editing. For enzymatic site-directed RNA editing, C-to-U editing has not yet been successfully performed, and in theory, adenosine to inosine (A-to-I) editing involves the same strategy as C-to-U editing. Therefore, in this review, for applications in transcript repair, we will provide a detailed overview of enzymatic site-directed RNA editing, with a focus on A-to-I editing and non-enzymatic site-directed C-to-U editing.

Meeting Special Educational Needs in Primary Classrooms: Inclusion and How to Do It. 2nd Edition

ERIC Educational Resources Information Center

Briggs, Sue

2016-01-01

There are greater numbers of children with Special Educational Needs and Disabilities (SEND) now attending mainstream schools. This fully updated and revised edition of "Meeting Special Educational Needs in Primary Classrooms" is written by an experienced teacher, adviser and SEN consultant and explains the challenges that these children…

The Humanities: A Selective Guide to Information Sources. Fifth Edition. Library and Information Science Text Series.

ERIC Educational Resources Information Center

Blazek, Ron; Aversa, Elizabeth

This book provides a guide to humanities information sources for teachers and students in schools of library and information science, reference librarians, collection development officers in libraries, humanities scholars, and others who have information needs in the broad discipline. This fifth edition represents a more comprehensive and updated…

International Education: Values and Perspectives on...Four Human Rights. Teacher Edition.

ERIC Educational Resources Information Center

American Federation of Teachers, Washington, DC.

This handbook is for use in teacher center or school district inservice programs designed to raise the levels of teacher interest, understanding, and involvement in incorporating international education into the curricula of the public schools. The introduction in the first section provides background information on the use of the guide and…

Alternative Splicing of STAT3 Is Affected by RNA Editing.

PubMed

Goldberg, Lior; Abutbul-Amitai, Mor; Paret, Gideon; Nevo-Caspi, Yael

2017-05-01

A-to-I RNA editing, carried out by adenosine deaminase acting on RNA (ADAR) enzymes, is an epigenetic phenomenon of posttranscriptional modifications on pre-mRNA. RNA editing in intronic sequences may influence alternative splicing of flanking exons. We have previously shown that conditions that induce editing result in elevated expression of signal transducer and activator of transcription 3 (STAT3), preferentially the alternatively-spliced STAT3β isoform. Mechanisms regulating alternative splicing of STAT3 have not been elucidated. STAT3 undergoes A-to-I RNA editing in an intron residing in proximity to the alternatively spliced exon. We hypothesized that RNA editing plays a role in regulating alternative splicing toward STAT3β. In this study we extend our observation connecting RNA editing to the preferential induction of STAT3β expression. We study the involvement of ADAR1 in STAT3 editing and reveal the connection between editing and alternative splicing of STAT3. Deferoaxamine treatment caused the induction in STAT3 RNA editing and STAT3β expression. Silencing ADAR1 caused a decrease in STAT3 editing and expression with a preferential decrease in STAT3β. Cells transfected with a mutated minigene showed preferential splicing toward the STAT3β transcript. Editing in the STAT3 intron is performed by ADAR1 and affects STAT3 alternative splicing. These results suggest that RNA editing is one of the molecular mechanisms regulating the expression of STAT3β.

Focusing on Teacher Learning Opportunities to Identify Potentially Productive Coaching Activities

ERIC Educational Resources Information Center

Gibbons, Lynsey K.; Cobb, Paul

2017-01-01

Instructional improvement initiatives in many districts include instructional coaching as a primary form of job-embedded support for teachers. However, the coaching literature provides little guidance about what activities coaches should engage in with teachers to improve instruction. When researchers do propose activities, they rarely justify why…

Impact of Online Support for Teachers' Open-Ended Questioning in Pre-K Science Activities

ERIC Educational Resources Information Center

Lee, Youngju; Kinzie, Mable B.; Whittaker, Jessica Vick

2012-01-01

We examined the effects of teacher supports in enhancing teachers' open-ended questioning in pre-k activities. The blended teacher supports included online video demonstrations of questioning techniques and companion workshop activities. Twenty-five teachers received the blended supports while the control group did not. The data consisted of…

Determinants of Teachers' Intentions To Teach Physically Active Physical Education Classes.

ERIC Educational Resources Information Center

Martin, Jeffrey J.; Kulinna, Pamela Hodges; Eklund, Robert C.; Reed, Brett

2001-01-01

Investigated elementary and secondary teachers' intentions to teach physically active physical education classes, examining a model hypothesizing that teachers' intentions were determined by subjective norm, attitude, perceived behavioral control, and self-efficacy. Teacher surveys supported the theories of reasoned action and planned behavior.…

The Teacher as Re-Designer of Technology Integrated Activities for an Early Literacy Curriculum

ERIC Educational Resources Information Center

Cviko, Amina; McKenney, Susan; Voogt, Joke

2013-01-01

Though popular among children outside of school, Dutch teachers often struggle to offer technology integrated activities in the kindergarten classroom. Because involving teachers in development of technology integrated activities can support their implementation, this study examines teachers in the role of re-designing such activities. Two case…

The Role of Physical Educators in Helping Classroom Teachers to Promote Physical Activity

ERIC Educational Resources Information Center

Russ, Laura

2015-01-01

Elementary classroom teachers are an increasingly important constituency in school-based physical activity promotion. This article situates the need for classroom teacher physical-activity promotion at the intersection of what we know about teacher actions, what informs those actions, and what recent research has uncovered. Recommendations are…

Star Trek with Latin. Teacher's Guide. Tentative Edition.

ERIC Educational Resources Information Center

Masciantonio, Rudolph; And Others

The purpose of this guide is to assist Latin and English teachers with some background in Latin to expand the English vocabulary and reading skills of students through the study of Latin roots, prefixes, and suffixes. The introductory material in the guide provides general notes on the teaching of Latin in the Philadelphia School District,…

Traffic Flow. USMES Teacher's Resource Book, Preliminary Edition.

ERIC Educational Resources Information Center

Education Development Center, Inc., Newton, MA.

This USMES unit challenges students to recommend and try to have a new road design or a system for rerouting traffic accepted so that cars and trucks can move safely at a reasonable speed through a busy intersection near the school. The teacher resource book for the Traffic Flow unit contains five sections. The first section describes the USMES…

Chemistry and the Periodic Table: Teacher's Guide Levels A, B, and C. Preliminary Limited Edition.

ERIC Educational Resources Information Center

Cambridge Physics Outlet, Woburn, MA. Education Programs Dept.

This is a two-part curriculum package for the teaching of chemistry and the periodic table. The first part, the Teacher's Guide, contains information necessary for using the equipment in a typical classroom including learning goals, vocabulary, math skills, and sample data for each activity. The second part of the package consists of photocopy…

RNA editing: trypanosomes rewrite the genetic code.

PubMed

Stuart, K

1998-01-01

The understanding of how genetic information is stored and expressed has advanced considerably since the "central dogma" asserted that genetic information flows from the nucleotide sequence of DNA to that of messenger RNA (mRNA) which in turn specifies the amino acid sequence of a protein. It was found that genetic information can be stored as RNA (e.g. in RNA viruses) and can flow from RNA to DNA by reverse transcriptase enzyme activity. In addition, some genes contain introns, nucleotide sequences that are removed from their RNA (by RNA splicing) and thus are not represented in the resultant protein. Furthermore, alternative splicing was found to produce variant proteins from a single gene. More recently, the study of trypanosome parasites revealed an unexpected and indeed counter-intuitive genetic complexity. Genetic information for a single protein can be dispersed among several (DNA) genes in these organisms. One of these genes specifies an encrypted precursor mRNA that is converted to a functional mRNA by a process called RNA editing that inserts and deletes uridylate nucleotides. The sequence of the edited mRNA is specified by multiple small RNAs, named guide RNAs, (gRNAs) each of which is encoded in a separate gene. Thus, edited mRNA sequences are assembled from multiple genes by the transfer of information from one type of RNA to another. The existence of editing was surprising but has stimulated the discovery of other types of RNA editing. The Stuart laboratory has been exploring RNA editing in trypanosomes from the time of its discovery. They found dramatic differences between the mitochondrial gene sequences and those of the corresponding mRNAs, which indicated editing by the insertion and deletion of uridylates. Some editing was modest; simply eliminating shifts in sequence register of minimally extending the protein coding sequence. However, editing of many mRNAs was startingly extensive. The RNA sequence was essentially entirely remodeled with its

Reaching and Teaching Students in Poverty: Strategies for Erasing the Opportunity Gap. Second Edition. Multicultural Education Series

ERIC Educational Resources Information Center

Gorski, Paul C.

2017-01-01

This influential book describes the knowledge and skills teachers and school administrators need to recognize and combat bias and inequity that undermine educational engagement for students experiencing poverty. The Second Edition features two new chapters--"Embracing a Structural View of Poverty and Education: Ditching Deficit Ideology and…

Educating Everybody's Children: Diverse Teaching Strategies for Diverse Learners, Revised and Expanded 2nd Edition

ERIC Educational Resources Information Center

Cole, Robert W.

2008-01-01

Since its first publication in 1995, hundreds of thousands of teachers in every grade and subject have benefited from this landmark guide on how to teach students from economically, ethnically, culturally, and linguistically diverse groups. Now at last, this all-new and expanded edition--nearly twice the size of the original--explains how these…

Reliability and Validity of the Early Childhood Environment Rating Scale, Revised Edition, ECERS-R in Arabic

ERIC Educational Resources Information Center

Hadeed, Julie

2014-01-01

The aim of this study was to test reliabilities and validations for the Arabic translation of the Early Childhood Environment Rating Scale, Revised (ECERS-R) scale [Harms, T., Clifford, R. M., & Cryer, D. (1998). "Early childhood environment rating scale, revised edition." New York: Teachers College Press]. ECERS-R mean scores were…

Review and Analysis of the EU Teacher-Related Policies and Activities

ERIC Educational Resources Information Center

Stéger, Csilla

2014-01-01

This article aims at raising awareness of the key role the EU already plays in matters of teacher policy. It takes stock of European teacher policy related documents and activities, such as relevant strategies, presidency priorities, Council Conclusions, Commission working documents, the activities of thematic working groups, of networks, of data…

DNA and RNA editing of retrotransposons accelerate mammalian genome evolution.

PubMed

Knisbacher, Binyamin A; Levanon, Erez Y

2015-04-01

Genome evolution is commonly viewed as a gradual process that is driven by random mutations that accumulate over time. However, DNA- and RNA-editing enzymes have been identified that can accelerate evolution by actively modifying the genomically encoded information. The apolipoprotein B mRNA editing enzymes, catalytic polypeptide-like (APOBECs) are potent restriction factors that can inhibit retroelements by cytosine-to-uridine editing of retroelement DNA after reverse transcription. In some cases, a retroelement may successfully integrate into the genome despite being hypermutated. Such events introduce unique sequences into the genome and are thus a source of genomic innovation. adenosine deaminases that act on RNA (ADARs) catalyze adenosine-to-inosine editing in double-stranded RNA, commonly formed by oppositely oriented retroelements. The RNA editing confers plasticity to the transcriptome by generating many transcript variants from a single genomic locus. If the editing produces a beneficial variant, the genome may maintain the locus that produces the RNA-edited transcript for its novel function. Here, we discuss how these two powerful editing mechanisms, which both target inserted retroelements, facilitate expedited genome evolution. © 2015 New York Academy of Sciences.

The GIANT Encyclopedia of Science Activities for Children 3 to 6: More Than 600 Science Activities Written by Teachers for Teachers.

ERIC Educational Resources Information Center

Charner, Kathy, Ed.

This book presents science activities developed by teachers for children ages 3-6 years old. The activities aim to develop science skills including communication, observation, estimation, measurement, cause and effect, investigation, and evaluation in children by using their curiosity as a staring point. Activities include age suggestions, address…

The Structure of the Atom: Teacher's Guide Levels A, B, and C. Preliminary Limited Edition.

ERIC Educational Resources Information Center

Cambridge Physics Outlet, Woburn, MA. Education Programs Dept.

This is a two-part curriculum package for teaching the structure of atoms. The first part--the Teacher's Guide--contains information necessary for using the equipment in a typical classroom including learning goals, vocabulary, math skills, and sample data for each activity. The second part of the package consists of photocopy masters for a set of…

Designing laboratory activities in elementary school oriented to scientific approach for teachers SD-Kreatif Bojonegoro

NASA Astrophysics Data System (ADS)

Dwikoranto; Surasmi, W. A.; Suparto, A.; Tresnaningsih, S.; Sambada, D.; Setyowati, T.; Faqih, A.; Setiani, R.

2018-03-01

Important science lessons are introduced to elementary school students through inquiry. This training is important to do because one key determinant of succesful laboratory activities is teachers. This course aims to enable teachers to design an inquiry-based Laboratory Activity and be able to apply it in the classroom. The training was conducted at SD-Kreatif Bojonegoro by Modeling, Design Laboratory activities and Implementing. The results of Laboratory Activities designed to trace the seven aspects that can support the development of inquiry skills in either category. The teacher's response in this activity is positive. The conclusion of this training can improve the ability of teachers in designing and implementing laboratory activities of Science and then expected to positively affect the frequency of science laboratory activities. Usually teachers use learning by using this Laboratory Activity, it will be affected on the pattern of inquiry behavior to the students as well so that will achieve the expected goals. Teachers are expected to continue for other topics, even for other similarly characterized subjects. This habitation is important so that the teacher's skill in making Laboratory Activity continues to be well honed and useful for the students.

ExpEdit: a webserver to explore human RNA editing in RNA-Seq experiments.

PubMed

Picardi, Ernesto; D'Antonio, Mattia; Carrabino, Danilo; Castrignanò, Tiziana; Pesole, Graziano

2011-05-01

ExpEdit is a web application for assessing RNA editing in human at known or user-specified sites supported by transcript data obtained by RNA-Seq experiments. Mapping data (in SAM/BAM format) or directly sequence reads [in FASTQ/short read archive (SRA) format] can be provided as input to carry out a comparative analysis against a large collection of known editing sites collected in DARNED database as well as other user-provided potentially edited positions. Results are shown as dynamic tables containing University of California, Santa Cruz (UCSC) links for a quick examination of the genomic context. ExpEdit is freely available on the web at http://www.caspur.it/ExpEdit/.

A Classroom Teacher's Guide to Reading Improvement in Middle School Social Studies. Revised Edition. Resource Monograph No. 17.

ERIC Educational Resources Information Center

Guttinger, Hellen I., Ed.

The reading improvement activities in this handbook are intended for use by middle school social studies teachers. Focusing on study skills, vocabulary development, and comprehension development, the activities include (1) surveying social studies texts and content area reading materials, (2) outlining, (3) spelling, (4) syllabication, (5) word…

A Classroom Teacher's Guide to Reading Improvement in Middle School Language Arts. Revised Edition. Resource Monograph No. 18.

ERIC Educational Resources Information Center

Guttinger, Hellen I., Ed.

The reading improvement activities in this handbook are intended for use by middle school language arts teachers. Focusing on study skills, vocabulary development, and comprehension development, the activities include (1) surveying literary materials, (2) outlining, (3) spelling, (4) syllabication, (5) word recognition, (6) using synonyms, (7)…

The Effect of Creative Drama Activities on Candidate Teachers' Self- Directed Skills

ERIC Educational Resources Information Center

Kosucu, Emine; Hursen, Cigdem

2017-01-01

This research aimed to specify the effect of creative drama activities on candidate teachers' self-directed skills. 35 candidate teachers participated in this study in which a mixture of a qualitative and quantitative method was used. The results obtained from the research showed that creative drama activities are effective on candidate teachers'…

Teacher's Psycho-Diagnostic Activities in School Educational System

ERIC Educational Resources Information Center

Minakhmetova, Albina Z.; Pyanova, Ekaterina N.; Akhmetshina, Enze M.

2016-01-01

The urgency of the problem stated in the article stems from the fact that in modern conditions the study of the psycho-diagnostic component of the teacher's activities is relevant in practical terms, since the functions of these activities affect the efficiency of pedagogical activity and the educational process itself, including the effectiveness…

The agents of natural genome editing.

PubMed

Witzany, Guenther

2011-06-01

The DNA serves as a stable information storage medium and every protein which is needed by the cell is produced from this blueprint via an RNA intermediate code. More recently it was found that an abundance of various RNA elements cooperate in a variety of steps and substeps as regulatory and catalytic units with multiple competencies to act on RNA transcripts. Natural genome editing on one side is the competent agent-driven generation and integration of meaningful DNA nucleotide sequences into pre-existing genomic content arrangements, and the ability to (re-)combine and (re-)regulate them according to context-dependent (i.e. adaptational) purposes of the host organism. Natural genome editing on the other side designates the integration of all RNA activities acting on RNA transcripts without altering DNA-encoded genes. If we take the genetic code seriously as a natural code, there must be agents that are competent to act on this code because no natural code codes itself as no natural language speaks itself. As code editing agents, viral and subviral agents have been suggested because there are several indicators that demonstrate viruses competent in both RNA and DNA natural genome editing.

Non-viral delivery of genome-editing nucleases for gene therapy.

PubMed

Wang, M; Glass, Z A; Xu, Q

2017-03-01

Manipulating the genetic makeup of mammalian cells using programmable nuclease-based genome-editing technology has recently evolved into a powerful avenue that holds great potential for treating genetic disorders. There are four types of genome-editing nucleases, including meganucleases, zinc finger nucleases, transcription activator-like effector nucleases and clustered, regularly interspaced, short palindromic repeat-associated nucleases such as Cas9. These nucleases have been harnessed to introduce precise and specific changes of the genome sequence at virtually any genome locus of interest. The therapeutic relevance of these genome-editing technologies, however, is challenged by the safe and efficient delivery of nuclease into targeted cells. Herein, we summarize recent advances that have been made on non-viral delivery of genome-editing nucleases. In particular, we focus on non-viral delivery of Cas9/sgRNA ribonucleoproteins for genome editing. In addition, the future direction for developing non-viral delivery of programmable nucleases for genome editing is discussed.

Great Decisions [and] Great Decisions Activity Book. 1994 Edition.

ERIC Educational Resources Information Center

Hoepli, Nancy L., Ed.

This book discusses foreign policy issues and provides background information on current topics. This edition examines the following major issues: (1) "Conflict in Former Yugoslavia: Quest for Solutions" (Susan L. Woodward); (2) "South Africa: Forging a Democratic Union" (Jean Herskovits); (3) "Environmental Crisis in Former Soviet Bloc: Whose…

Why Change to Active Learning? Pre-Service and In-Service Science Teachers' Perceptions

ERIC Educational Resources Information Center

O'Grady, Audrey; Simmie, Geraldine Mooney; Kennedy, Therese

2014-01-01

This article explores pre-service and in-service science teachers' perceptions on active learning, and examines the effectiveness of active learning by pre-service science teachers in the Irish second level classroom through a two-phase study. In the first phase, data on perceptions were gathered from final year pre-service teachers and in-service…

Teacher's Resource Guide on Acidic Precipitation with Laboratory Activities.

ERIC Educational Resources Information Center

Barrow, Lloyd H.

The purpose of this teacher's resource guide is to help science teachers incorporate the topic of acidic precipitation into their curricula. A survey of recent junior high school science textbooks found a maximum of one paragraph devoted to the subject; in addition, none of these books had any related laboratory activities. It was on the basis of…

The Marginal Teacher: A Step-by-Step Guide to Fair Procedures for Identification and Dismissal

ERIC Educational Resources Information Center

Lawrence, C. Edward

2005-01-01

This third edition offers timely solutions for successfully dealing with marginal teachers. Lawrence illustrates the proper actions that principals should integrate into the evaluation processes to successfully gather documentation to help improve or terminate an ineffective teacher. Complete with tools and resources to streamline the evaluation…

Improving School Feeding through Participation: Should the Teacher Be Actively Involved?

ERIC Educational Resources Information Center

Iddrisu, Issah

2018-01-01

Purpose: Maintaining the success of educational institutions largely depends on the teacher. It is the teacher whose main efforts and contribution help in achieving the goals in education. The purpose of this paper is to examine the current state of the programme delivery and how involving the active participation of the teacher will help enhance…

The teachers at Sea program of the Committee on Education of EGU

NASA Astrophysics Data System (ADS)

Laj, Carlo; Kissel, Catherine; Leau, Hélène

2015-04-01

"Teachers at sea" is an Educational Program making it possible for high school teachers to participate to oceanographic cruises together with the scientists. With the support of the French Polar Insitute (IPEV) and of EGU, 3 editions of this program have taken place on board the R/V Marion Dufresne during cruises PACHIDERME in 2007 (along the Coast and in the fiords of Southern Chile), AMOCINT in 2008 (in the North Atlantic Ocean), and CIRCEA (in the South China Sea in 2012) Another edition took place in 2014, aboard the oceanographic cruise PREPARED (PREsent and PAst flow REgime on contourite Drifts west of Spitsbergen, onboard the Norwegian Research Vessel G.O Sars from 05 to 15 June 2014. The expedition was part of the EUROFLEETS On board, the teachers participated to all the scientific activities. In order to be fully immersed in the scientific work, the teachers also participated together with the scientists and technicians to two 4-hours shifts per day (8h total per day). During these shifts, they were involved in every step of the process of obtaining the cores, cutting, opening and labelling them, archiving, and measuring some of the physical parameters, and finally sediment description. It was possible to establish almost daily reports of the scientific progress of the cruise and to send regular logs to the participating land-based teachers in different schools mainly in Europe and in the USA, taking advantage of a list of addresses of teachers having participated to the Geosciences Information for teachers (GIFT) workshops of the European Geosciences Union. This should bring authentic science in the classroom, and indeed we received enthusiastic responses from many teachers. Exposure to authentic science, such as that the teachers have experienced during these oceanographic cruises, may be a pivotal experience for them, causing them to change at least in part their teaching methods, possibly creating more future scientists or at least adults with positive

Can You Tube It? Providing Chemistry Teachers with Technological Tools and Enhancing Their Self-Efficacy Beliefs

ERIC Educational Resources Information Center

Blonder, Ron; Jonatan, Moshe; Bar-Dov, Ziva; Benny, Naama; Rap, Shelley; Sakhnini, Sohair

2013-01-01

The goal of this research was to examine the change in the skills, Technological Pedagogical Content Knowledge (TPACK) and self-efficacy beliefs of chemistry teachers regarding video editing and using YouTube videos in high-school chemistry lessons, as a result of a professional development program that focused on editing YouTube videos and the…

Jelly Jam, the People Preserver. Teaching Guide. An Environmental Manual for Teachers and Parents. Revised Edition.

ERIC Educational Resources Information Center

Friedman, Judi

Designed for teachers of students in grades 2 through 4, this teaching guide for a self-teaching, interdisciplinary reading and activity program comprises a complete supplemental reading, science, and social studies approach to the problems of environmental pollution. Jelly Jam, a caring little animal, helps children understand how air, water, and…

SCDC Spanish Curricula Units. Social Science Strand, Unit 2, Grade One, Teacher's Guide--Multi-Ethnic Edition.

ERIC Educational Resources Information Center

Spanish Curricula Development Center, Miami Beach, FL.

Building on a unit designed to help first graders adjust to the classroom environment, this teacher's guide for the second bilingual social science instructional unit includes material which expands the conceptual field of the child to the family. The Spanish-English guide presents instructional and assessment activities for kits five through…

A 'new lease of life': FnCpf1 possesses DNA cleavage activity for genome editing in human cells.

PubMed

Tu, Mengjun; Lin, Li; Cheng, Yilu; He, Xiubin; Sun, Huihui; Xie, Haihua; Fu, Junhao; Liu, Changbao; Li, Jin; Chen, Ding; Xi, Haitao; Xue, Dongyu; Liu, Qi; Zhao, Junzhao; Gao, Caixia; Song, Zongming; Qu, Jia; Gu, Feng

2017-11-02

Cpf1 nucleases were recently reported to be highly specific and programmable nucleases with efficiencies comparable to those of SpCas9. AsCpf1 and LbCpf1 require a single crRNA and recognize a 5'-TTTN-3' protospacer adjacent motif (PAM) at the 5' end of the protospacer for genome editing. For widespread application in precision site-specific human genome editing, the range of sequences that AsCpf1 and LbCpf1 can recognize is limited due to the size of this PAM. To address this limitation, we sought to identify a novel Cpf1 nuclease with simpler PAM requirements. Specifically, here we sought to test and engineer FnCpf1, one reported Cpf1 nuclease (FnCpf1) only requires 5'-TTN-3' as a PAM but does not exhibit detectable levels of nuclease-induced indels at certain locus in human cells. Surprisingly, we found that FnCpf1 possesses DNA cleavage activity in human cells at multiple loci. We also comprehensively and quantitatively examined various FnCpf1 parameters in human cells, including spacer sequence, direct repeat sequence and the PAM sequence. Our study identifies FnCpf1 as a new member of the Cpf1 family for human genome editing with distinctive characteristics, which shows promise as a genome editing tool with the potential for both research and therapeutic applications. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

Unlocking Mathematics Teaching. Second Edition

ERIC Educational Resources Information Center

Koshy, Valsa, Ed.; Murray, Jean, Ed.

2011-01-01

Now in a fully updated second edition, "Unlocking Mathematics Teaching" is a comprehensive guide to teaching mathematics in the primary school. Combining theory and practice, selected experts outline the current context of mathematics education. They suggest strategies, activities and examples to help develop readers understanding and confidence…

The Development of a Physical Education Teachers' Physical Activity Self-Efficacy Instrument.

ERIC Educational Resources Information Center

Martin, Jeffrey J.; Kulinna, Pamela Hodges

2003-01-01

Developed a valid, reliable physical education teachers' physical activity self-efficacy scale for teaching classes in which students were engaged in high levels of physical activity. Results offer preliminary support for the psychometric properties of this instrument, which can help understand physical education teachers' efficacy in overcoming…

Mitochondrial tRNA 5'-editing in Dictyostelium discoideum and Polysphondylium pallidum.

PubMed

Abad, Maria G; Long, Yicheng; Kinchen, R Dimitri; Schindel, Elinor T; Gray, Michael W; Jackman, Jane E

2014-05-30

Mitochondrial tRNA (mt-tRNA) 5'-editing was first described more than 20 years ago; however, the first candidates for 5'-editing enzymes were only recently identified in a eukaryotic microbe (protist), the slime mold Dictyostelium discoideum. In this organism, eight of 18 mt-tRNAs are predicted to be edited based on the presence of genomically encoded mismatched nucleotides in their aminoacyl-acceptor stem sequences. Here, we demonstrate that mt-tRNA 5'-editing occurs at all predicted sites in D. discoideum as evidenced by changes in the sequences of isolated mt-tRNAs compared with the expected sequences encoded by the mitochondrial genome. We also identify two previously unpredicted editing events in which G-U base pairs are edited in the absence of any other genomically encoded mismatches. A comparison of 5'-editing in D. discoideum with 5'-editing in another slime mold, Polysphondylium pallidum, suggests organism-specific idiosyncrasies in the treatment of U-G/G-U pairs. In vitro activities of putative D. discoideum editing enzymes are consistent with the observed editing reactions and suggest an overall lack of tRNA substrate specificity exhibited by the repair component of the editing enzyme. Although the presence of terminal mismatches in mt-tRNA sequences is highly predictive of the occurrence of mt-tRNA 5'-editing, the variability in treatment of U-G/G-U base pairs observed here indicates that direct experimental evidence of 5'-editing must be obtained to understand the complete spectrum of mt-tRNA editing events in any species. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

Improving Teacher Feedback during Active Learning: Effects of a Professional Development Program

ERIC Educational Resources Information Center

Van den Bergh, Linda; Ros, Anje; Beijaard, Douwe

2014-01-01

This study focuses on improving teacher feedback during active learning. Changing teachers' behavior sustainably, however, is very difficult. Several conditions should be taken into account, and programs should build on teachers' cognitions and practices. Effects of a specifically designed professional development program on 16 elementary…

Solar Physics and Terrestrial Effects: A Curriculum Guide for Teachers Grades 7-12, 2nd Edition.

ERIC Educational Resources Information Center

Briggs, Roger P.; Carlisle, Robert J.

This curriculum guide includes a brief textbook, a hands-on activity guide, and resource listings. The textbook provides background information in solar physics for teachers and contains problems suitable for advanced students at the end of each chapter. Topics covered in the textbook include stellar evolution, the structure of the sun, methods of…

Examining the Knowledge and Capacity of Elementary Teachers to Implement Classroom Physical Activity Breaks

ERIC Educational Resources Information Center

Dinkel, Danae M.; Lee, Jung-Min; Schaffer, Connie

2016-01-01

This study examined teachers' zone of proximal development for classroom physical activity breaks by assessing teachers' knowledge and capacity for implementing classroom physical activity breaks. Five school districts of various sizes (n = 346 teachers) took part in a short online survey. Descriptive statistics were calculated and chi-square…

Decreased A-to-I RNA editing as a source of keratinocytes' dsRNA in psoriasis.

PubMed

Shallev, Lea; Kopel, Eli; Feiglin, Ariel; Leichner, Gil S; Avni, Dror; Sidi, Yechezkel; Eisenberg, Eli; Barzilai, Aviv; Levanon, Erez Y; Greenberger, Shoshana

2018-06-01

Recognition of dsRNA molecules activates the MDA5-MAVS pathway and plays a critical role in stimulating type-I interferon responses in psoriasis. However, the source of the dsRNA accumulation in psoriatic keratinocytes remains largely unknown. A-to-I RNA editing is a common co- or post-transcriptional modification that diversifies adenosine in dsRNA, and leads to unwinding of dsRNA structures. Thus, impaired RNA editing activity can result in an increased load of endogenous dsRNAs. Here we provide a transcriptome-wide analysis of RNA editing across dozens of psoriasis patients, and we demonstrate a global editing reduction in psoriatic lesions. In addition to the global alteration, we also detect editing changes in functional recoding sites located in the IGFBP7 , COPA , and FLNA genes. Accretion of dsRNA activates autoimmune responses, and therefore the results presented here, linking for the first time an autoimmune disease to reduction in global editing level, are relevant to a wide range of autoimmune diseases. © 2018 Shallev et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

Re-editing the paradigm of Cytidine (C) to Uridine (U) RNA editing.

PubMed

Fossat, Nicolas; Tam, Patrick P L

2014-01-01

Cytidine (C) to Uridine (U) RNA editing is a post-trancriptional modification that until recently was known to only affect Apolipoprotein b (Apob) RNA and minimally require 2 components of the C to U editosome, the deaminase APOBEC1 and the RNA-binding protein A1CF. Our latest work has identified a novel RNA-binding protein, RBM47, as a core component of the editosome, which can substitute A1CF for the editing of ApoB mRNA. In addition, new RNA species that are subjected to C to U editing have been identified. Here, we highlight these recent discoveries and discuss how they change our view of the composition of the C to U editing machinery and expand our knowledge of the functional attributes of C to U RNA editing.

A Curriculum Activities Guide to Birds, Bugs, Dogs, and Weather and Environmental Studies. Volume 5. 2nd Edition.

ERIC Educational Resources Information Center

Hershey, John T.; And Others

This material is one publication of a series of documents available from the Institute for Environmental Education (Cleveland) and consists of a curriculum activities guide to birds, bugs, dogs, and weather and environmental studies. The first edition of this material was prepared by the Documentation Task Force of Project KARE, Philadelphia, and…

Genome-editing Technologies for Gene and Cell Therapy.

PubMed

Maeder, Morgan L; Gersbach, Charles A

2016-03-01

Gene therapy has historically been defined as the addition of new genes to human cells. However, the recent advent of genome-editing technologies has enabled a new paradigm in which the sequence of the human genome can be precisely manipulated to achieve a therapeutic effect. This includes the correction of mutations that cause disease, the addition of therapeutic genes to specific sites in the genome, and the removal of deleterious genes or genome sequences. This review presents the mechanisms of different genome-editing strategies and describes each of the common nuclease-based platforms, including zinc finger nucleases, transcription activator-like effector nucleases (TALENs), meganucleases, and the CRISPR/Cas9 system. We then summarize the progress made in applying genome editing to various areas of gene and cell therapy, including antiviral strategies, immunotherapies, and the treatment of monogenic hereditary disorders. The current challenges and future prospects for genome editing as a transformative technology for gene and cell therapy are also discussed.

Genome-editing Technologies for Gene and Cell Therapy

PubMed Central

Maeder, Morgan L; Gersbach, Charles A

2016-01-01

Gene therapy has historically been defined as the addition of new genes to human cells. However, the recent advent of genome-editing technologies has enabled a new paradigm in which the sequence of the human genome can be precisely manipulated to achieve a therapeutic effect. This includes the correction of mutations that cause disease, the addition of therapeutic genes to specific sites in the genome, and the removal of deleterious genes or genome sequences. This review presents the mechanisms of different genome-editing strategies and describes each of the common nuclease-based platforms, including zinc finger nucleases, transcription activator-like effector nucleases (TALENs), meganucleases, and the CRISPR/Cas9 system. We then summarize the progress made in applying genome editing to various areas of gene and cell therapy, including antiviral strategies, immunotherapies, and the treatment of monogenic hereditary disorders. The current challenges and future prospects for genome editing as a transformative technology for gene and cell therapy are also discussed. PMID:26755333

The Impact of Continuity Editing in Narrative Film on Event Segmentation

PubMed Central

Magliano, Joseph P.; Zacks, Jeffrey M.

2011-01-01

Filmmakers use continuity editing to engender a sense of situational continuity or discontinuity at editing boundaries. The goal of this study was to assess the impact of continuity editing on how people perceive the structure of events in a narrative film and to identify brain networks that are associated with the processing of different types of continuity editing boundaries. Participants viewed a commercially produced film and segmented it into meaningful events while brain activity was recorded with functional MRI. We identified three degrees of continuity that can occur at editing locations: edits that are continuous in space, time, and action; edits that are discontinuous in space or time but continuous in action; and edits that are discontinuous in action as well as space or time. Discontinuities in action had the biggest impact on behavioral event segmentation and discontinuities in space and time had minor effects. Edits were associated with large transient increases in early visual areas. Spatial-temporal changes and action changes produced strikingly different patterns of transient change, and provided evidence that specialized mechanisms in higher-order perceptual processing regions are engaged to maintain continuity of action in the face of spatiotemporal discontinuities. These results suggest that commercial film editing is shaped to support the comprehension of meaningful events that bridge breaks in low-level visual continuity, and even breaks in continuity of spatial and temporal location. PMID:21972849

Convergent Validity with the BERS-2 Teacher Rating Scale and the Achenbach Teacher's Report Form: A Replication and Extension

ERIC Educational Resources Information Center

Benner, Gregory J.; Beaudoin, Kathleen; Mooney, Paul; Uhing, Brad M.; Pierce, Corey D.

2008-01-01

In the present study, we sought to extend instrument validation research for a strength-based emotional and behavior rating scale, the "Teacher Rating Scale of the Behavior and Emotional Rating Scale-Second Edition" (BERS-2; Epstein, M. H. (2004). "Behavioral and emotional rating scale" (2nd ed.). Austin, TX: PRO-ED) through…

Your Reading: An Annotated Booklist for Middle School and Junior High. 11th Edition. NCTE Bibliography Series.

ERIC Educational Resources Information Center

Brown, Jean E., Ed.; Stephens, Elaine C., Ed.

Organized around the theme of "challenges," the 11th edition of "Your Reading" offers annotations of more than 1,200 books for young adults. Intended for teachers, librarians, parents, and students, this booklist presents recently published books that can be read for many purposes--for sheer enjoyment of the story, to pique…

The Effects of the Mississippi Curriculum Test: Second Edition: A Study on the Teacher Morale and Teacher Efficacy of Seventh and Eighth Grade Teachers

ERIC Educational Resources Information Center

Willis, Mario

2014-01-01

The primary purpose of this study was to examine the effects that high-stakes tests have on middle school teachers' morale and teachers' efficacy in the state of Mississippi. The participants in this study were teachers in the areas of language arts, mathematics, and science at the middle school level. The researcher used a correlational design,…

Ebola virus RNA editing depends on the primary editing site sequence and an upstream secondary structure.

PubMed

Mehedi, Masfique; Hoenen, Thomas; Robertson, Shelly; Ricklefs, Stacy; Dolan, Michael A; Taylor, Travis; Falzarano, Darryl; Ebihara, Hideki; Porcella, Stephen F; Feldmann, Heinz

2013-01-01

Ebolavirus (EBOV), the causative agent of a severe hemorrhagic fever and a biosafety level 4 pathogen, increases its genome coding capacity by producing multiple transcripts encoding for structural and nonstructural glycoproteins from a single gene. This is achieved through RNA editing, during which non-template adenosine residues are incorporated into the EBOV mRNAs at an editing site encoding for 7 adenosine residues. However, the mechanism of EBOV RNA editing is currently not understood. In this study, we report for the first time that minigenomes containing the glycoprotein gene editing site can undergo RNA editing, thereby eliminating the requirement for a biosafety level 4 laboratory to study EBOV RNA editing. Using a newly developed dual-reporter minigenome, we have characterized the mechanism of EBOV RNA editing, and have identified cis-acting sequences that are required for editing, located between 9 nt upstream and 9 nt downstream of the editing site. Moreover, we show that a secondary structure in the upstream cis-acting sequence plays an important role in RNA editing. EBOV RNA editing is glycoprotein gene-specific, as a stretch encoding for 7 adenosine residues located in the viral polymerase gene did not serve as an editing site, most likely due to an absence of the necessary cis-acting sequences. Finally, the EBOV protein VP30 was identified as a trans-acting factor for RNA editing, constituting a novel function for this protein. Overall, our results provide novel insights into the RNA editing mechanism of EBOV, further understanding of which might result in novel intervention strategies against this viral pathogen.

In Search of the Eco-Teacher: Public School Edition

ERIC Educational Resources Information Center

Blenkinsop, Sean

2014-01-01

This paper uses an innovative building-less Canadian public elementary school and its accompanying large-scale research project to consider the characteristics that might be required of a teacher interested in working in an emergent, environmental, place- and community-based experiential public school setting. The six characteristics considered…

Engineered Viruses as Genome Editing Devices

PubMed Central

Chen, Xiaoyu; Gonçalves, Manuel A F V

2016-01-01

Genome editing based on sequence-specific designer nucleases, also known as programmable nucleases, seeks to modify in a targeted and precise manner the genetic information content of living cells. Delivering into cells designer nucleases alone or together with donor DNA templates, which serve as surrogate homologous recombination (HR) substrates, can result in gene knockouts or gene knock-ins, respectively. As engineered replication-defective viruses, viral vectors are having an increasingly important role as delivery vehicles for donor DNA templates and designer nucleases, namely, zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and clustered, regularly interspaced, short palindromic repeats (CRISPR)-associated Cas9 (CRISPR−Cas9) nucleases, also known as RNA-guided nucleases (RGNs). We review this dual role played by engineered viral particles on genome editing while focusing on their main scaffolds, consisting of lentiviruses, adeno-associated viruses, and adenoviruses. In addition, the coverage of the growing body of research on the repurposing of viral vectors as delivery systems for genome editing tools is complemented with information regarding their main characteristics, pros, and cons. Finally, this information is framed by a concise description of the chief principles, tools, and applications of the genome editing field as a whole. PMID:26336974

Engineered Viruses as Genome Editing Devices.

PubMed

Chen, Xiaoyu; Gonçalves, Manuel A F V

2016-03-01

Genome editing based on sequence-specific designer nucleases, also known as programmable nucleases, seeks to modify in a targeted and precise manner the genetic information content of living cells. Delivering into cells designer nucleases alone or together with donor DNA templates, which serve as surrogate homologous recombination (HR) substrates, can result in gene knockouts or gene knock-ins, respectively. As engineered replication-defective viruses, viral vectors are having an increasingly important role as delivery vehicles for donor DNA templates and designer nucleases, namely, zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and clustered, regularly interspaced, short palindromic repeats (CRISPR)-associated Cas9 (CRISPR-Cas9) nucleases, also known as RNA-guided nucleases (RGNs). We review this dual role played by engineered viral particles on genome editing while focusing on their main scaffolds, consisting of lentiviruses, adeno-associated viruses, and adenoviruses. In addition, the coverage of the growing body of research on the repurposing of viral vectors as delivery systems for genome editing tools is complemented with information regarding their main characteristics, pros, and cons. Finally, this information is framed by a concise description of the chief principles, tools, and applications of the genome editing field as a whole.

Genome Editing in Human Pluripotent Stem Cells.

PubMed

Carlson-Stevermer, Jared; Saha, Krishanu

2017-01-01

Genome editing in human pluripotent stem cells (hPSCs) enables the generation of reporter lines and knockout cell lines. Zinc finger nucleases, transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9 technology have recently increased the efficiency of proper gene editing by creating double strand breaks (DSB) at defined sequences in the human genome. These systems typically use plasmids to transiently transcribe nucleases within the cell. Here, we describe the process for preparing hPSCs for transient expression of nucleases via electroporation and subsequent analysis to create genetically modified stem cell lines.

Genome editing: a robust technology for human stem cells.

PubMed

Chandrasekaran, Arun Pandian; Song, Minjung; Ramakrishna, Suresh

2017-09-01

Human pluripotent stem cells comprise induced pluripotent and embryonic stem cells, which have tremendous potential for biological and therapeutic applications. The development of efficient technologies for the targeted genome alteration of stem cells in disease models is a prerequisite for utilizing stem cells to their full potential. Genome editing of stem cells is possible with the help of synthetic nucleases that facilitate site-specific modification of a gene of interest. Recent advances in genome editing techniques have improved the efficiency and speed of the development of stem cells for human disease models. Zinc finger nucleases, transcription activator-like effector nucleases, and clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated system are powerful tools for editing DNA at specific loci. Here, we discuss recent technological advances in genome editing with site-specific nucleases in human stem cells.

Teachers as Co-Designers of Technology-Rich Learning Activities for Early Literacy

ERIC Educational Resources Information Center

Cviko, Amina; McKenney, Susan; Voogt, Joke

2015-01-01

Although kindergarten teachers often struggle with implementing technology, they are rarely involved in co-designing technology-rich learning activities. This study involved teachers in the co-design of technology-rich learning activities and sought to explore implementation and pupil learning outcomes. A case-study method was used to investigate:…

Understanding Editing Behaviors in Multilingual Wikipedia.

PubMed

Kim, Suin; Park, Sungjoon; Hale, Scott A; Kim, Sooyoung; Byun, Jeongmin; Oh, Alice H

2016-01-01

Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary) languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language.

Understanding Editing Behaviors in Multilingual Wikipedia

PubMed Central

Hale, Scott A.; Kim, Sooyoung; Byun, Jeongmin; Oh, Alice H.

2016-01-01

Multilingualism is common offline, but we have a more limited understanding of the ways multilingualism is displayed online and the roles that multilinguals play in the spread of content between speakers of different languages. We take a computational approach to studying multilingualism using one of the largest user-generated content platforms, Wikipedia. We study multilingualism by collecting and analyzing a large dataset of the content written by multilingual editors of the English, German, and Spanish editions of Wikipedia. This dataset contains over two million paragraphs edited by over 15,000 multilingual users from July 8 to August 9, 2013. We analyze these multilingual editors in terms of their engagement, interests, and language proficiency in their primary and non-primary (secondary) languages and find that the English edition of Wikipedia displays different dynamics from the Spanish and German editions. Users primarily editing the Spanish and German editions make more complex edits than users who edit these editions as a second language. In contrast, users editing the English edition as a second language make edits that are just as complex as the edits by users who primarily edit the English edition. In this way, English serves a special role bringing together content written by multilinguals from many language editions. Nonetheless, language remains a formidable hurdle to the spread of content: we find evidence for a complexity barrier whereby editors are less likely to edit complex content in a second language. In addition, we find that multilinguals are less engaged and show lower levels of language proficiency in their second languages. We also examine the topical interests of multilingual editors and find that there is no significant difference between primary and non-primary editors in each language. PMID:27171158

Teachers' Choice of Using Practical Activities--A Hierarchical Classification Attempt

ERIC Educational Resources Information Center

Haara, Frode Olav

2015-01-01

From a system theoretically grounded point of view, a hierarchy of primary and secondary impact factors influencing the mathematics teacher's choice to use practical activities in mathematics teaching is suggested initially in the article. A study, based on qualitative responses from mathematics teachers, then gives grounds for suggesting that a…

Aerospace and Flight. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on aerospace and flight for students in grades 6-10 consists of a technology education overview, information on use, and instructor's and student's sections. The overview discusses the technology education program and materials. Components of the instructor's and student's sections are…

Introduction to Animation. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This packet of technology learning activity (TLA) materials on introduction to animation for students in grades 6-10 consists of a technology education overview, information on use, and the instructor's and student's sections. The overview discusses the technology education program and materials. Section components are described next. The…

Obama Proposes Teacher Results in Federal Law

ERIC Educational Resources Information Center

Sawchuk, Stephen

2010-01-01

In its fiscal 2011 budget request, the Obama administration has laid out its intention of carrying forward key teacher-effectiveness policies within the economic-stimulus law into the next edition of the Elementary and Secondary Education Act. In doing so, the budget proposal would invest heavily in competitive grants for new ways of recruiting,…

School Law for Kentucky Teachers and Administrators. Third Edition.

ERIC Educational Resources Information Center

Faber, Charles F.; And Others

Intended for use in school law courses of a primarily informative nature with some attention given to attitudinal concerns, this book was designed for teachers and educational administrators. The contents are divided into 13 units that contain information regarding education and the American legal system, certification and employment, religion and…

Classical Civilization (Greece-Hellenistic-Rome). Teacher's Manual. 1968 Edition.

ERIC Educational Resources Information Center

Leppert, Ella C.; Smith, Rozella B.

This secondary teachers guide builds upon a previous sequential course described in SO 003 173, and consists of three sections on the classical civilizations--Greek, Hellenistic, and Rome. Major emphasis is upon students gaining an understanding of cultural development and transmission. Using an analytic method, students learn to examine primary…

BIOINFORMATICS IN THE K-8 CLASSROOM: DESIGNING INNOVATIVE ACTIVITIES FOR TEACHER IMPLEMENTATION

PubMed Central

Shuster, Michele; Claussen, Kira; Locke, Melly; Glazewski, Krista

2016-01-01

At the intersection of biology and computer science is the growing field of bioinformatics—the analysis of complex datasets of biological relevance. Despite the increasing importance of bioinformatics and associated practical applications, these are not standard topics in elementary and middle school classrooms. We report on a pilot project and its evolution to support implementation of bioinformatics-based activities in elementary and middle school classrooms. Specifically, we ultimately designed a multi-day summer teacher professional development workshop, in which teachers design innovative classroom activities. By focusing on teachers, our design leverages enhanced teacher knowledge and confidence to integrate innovative instructional materials into K-8 classrooms and contributes to capacity building in STEM instruction. PMID:27429860

SCDC Spanish Curricula Units. Science/Math Strand, Unit 8, Grade 3, Teacher's Guide--Multi-Ethnic Edition.

ERIC Educational Resources Information Center

Spanish Curricula Development Center, Miami Beach, FL.

Built around a theme of communities in the nation, this teacher's guide for unit eight of a science/math strand for Spanish-speaking children in grade three contains both learning and assessment activities. This unit addresses what the elements are, how needs and wants are satisfied, how change occurs, and what the results of change are. The guide…

Recognition of RNA Editing Sites Is Directed by Unique Proteins in Chloroplasts: Biochemical Identification of cis-Acting Elements and trans-Acting Factors Involved in RNA Editing in Tobacco and Pea Chloroplasts

PubMed Central

Miyamoto, Tetsuya; Obokata, Junichi; Sugiura, Masahiro

2002-01-01

RNA editing in higher-plant chloroplasts involves C-to-U conversions at specific sites. Although in vivo analyses have been performed, little is known about the biochemical aspects of chloroplast editing reactions. Here we improved our original in vitro system and devised a procedure for preparing active chloroplast extracts not only from tobacco plants but also from pea plants. Using our tobacco in vitro system, cis-acting elements were defined for psbE and petB mRNAs. Distinct proteins were found to bind specifically to each cis-element, a 56-kDa protein to the psbE site and a 70-kDa species to the petB site. Pea chloroplasts lack the corresponding editing site in psbE since T is already present in the DNA. Parallel in vitro analyses with tobacco and pea extracts revealed that the pea plant has no editing activity for psbE mRNAs and lacks the 56-kDa protein, whereas petB mRNAs are edited and the 70-kDa protein is also present. Therefore, coevolution of an editing site and its cognate trans-factor was demonstrated biochemically in psbE mRNA editing between tobacco and pea plants. PMID:12215530