Science.gov

Sample records for actores pro tabaco

  1. Actors: From Audience to Provider

    ERIC Educational Resources Information Center

    Charlier, Bernadette

    2011-01-01

    This article describes and analyzes actors' experiences of distance learning systems in a wide variety of cultural and organizational contexts. In line with the project of this special series of issues, results of research, much of which is longitudinal, allow us to suggest answers to the following questions: Who are the actors of distance…

  2. You're a What? Voice Actor

    ERIC Educational Resources Information Center

    Liming, Drew

    2009-01-01

    This article talks about voice actors and features Tony Oliver, a professional voice actor. Voice actors help to bring one's favorite cartoon and video game characters to life. They also do voice-overs for radio and television commercials and movie trailers. These actors use the sound of their voice to sell a character's emotions--or an advertised…

  3. Multicultural Monologues for Young Actors. The Young Actors Series.

    ERIC Educational Resources Information Center

    Slaight, Craig, Ed.; Sharrar, Jack, Ed.

    This book presents 62 monologue selections from diverse cultures for young actors to perform. The book's selections offer "quality literature by significant writers." Some of the writers represented in the book are George C. Wolfe, Miguel Pinero, Lorraine Hansberry, Amiri Baraka (LeRoi Jones), John M. Synge, Yukio Mishima, Reynolds Price, and John…

  4. The Actor and His Body.

    ERIC Educational Resources Information Center

    Rubin, Lucille S., Ed.

    Fourteen brief articles deal with training actors to use their bodies effectively on stage. The articles discuss the following topics: the concept of succession-sequential movement (movement that passes through the body joint by joint); learning physical action through staged fight sequences; techniques of empty-handed combat; protecting students…

  5. Actor Interdependence in Collaborative Telelearning.

    ERIC Educational Resources Information Center

    Wasson, Barbara; Bourdeau, Jacqueline

    This paper presents a model of collaborative telelearning and describes how coordination theory has provided a framework for the analysis of actor (inter)dependencies in this scenario. The model is intended to inform the instructional design of learning scenarios, the technological design of the telelearning environment, and the design of…

  6. Changing Power Actors in a Midwestern Community.

    ERIC Educational Resources Information Center

    Tait, John L.; And Others

    A longitudinal study was made of Prairie City, Iowa wherein the personal and social characteristics of the 1962 power actor pool were compared with characteristics of the 1973 power actor pool to test the hypothesis that: the personal and social characteristics of power actors will not change significantly over time. Procedures for identifying…

  7. Privileged Emotion Managers: The Case of Actors

    ERIC Educational Resources Information Center

    Orzechowicz, David

    2008-01-01

    Theatre provides a unique set of conditions for the management of emotions. Drawing on participant observation from one repertory theater, three university productions, and interviews with stage actors, directors, and acting instructors, I conceptualize actors as privileged emotion managers. Actors access structural resources that enable their…

  8. Genie Pro

    Energy Science and Technology Software Center (ESTSC)

    2004-05-15

    Genie Pro is a general purpose, interactive, adaptive tool for automatically labeling regions and finding objects in large amounts of image data. Genie Pro uses supervised learning techniques to search for spatio-spectral algorithms that are best able to match exaple labels provided by a user during a training session. After Genie Pro has discovered a useful algorithm, this algorith can then be applied to other similar types of image data, to label regions and objectsmore » similar to those provided during the training session. Genie Pro was originally developed for analyzing multispectral satellite data, but it works equally well with panchromatic (grayscale) and hyperspectral satellite data, aerial imagery, and various kinds of medical imagery. AS a rough guideline, Genie Pro can work with any imagery where the scene being imaged is all approximately at a constant distance fromt he imaging device, and so the scale of imagery is fixed. Applications for Genie Pro include: Crop and terrain type mapping, Road and river network mapping, Broad area search for vehicles and buildings, and Cancer identification in histological images.« less

  9. Mesenchymal Stem Cells after Polytrauma: Actor and Target.

    PubMed

    Huber-Lang, Markus; Wiegner, Rebecca; Lampl, Lorenz; Brenner, Rolf E

    2016-01-01

    Mesenchymal stem cells (MSCs) are multipotent cells that are considered indispensable in regeneration processes after tissue trauma. MSCs are recruited to damaged areas via several chemoattractant pathways where they function as "actors" in the healing process by the secretion of manifold pro- and anti-inflammatory, antimicrobial, pro- and anticoagulatory, and trophic/angiogenic factors, but also by proliferation and differentiation into the required cells. On the other hand, MSCs represent "targets" during the pathophysiological conditions after severe trauma, when excessively generated inflammatory mediators, complement activation factors, and damage- and pathogen-associated molecular patterns challenge MSCs and alter their functionality. This in turn leads to complement opsonization, lysis, clearance by macrophages, and reduced migratory and regenerative abilities which culminate in impaired tissue repair. We summarize relevant cellular and signaling mechanisms and provide an up-to-date overview about promising future therapeutic MSC strategies in the context of severe tissue trauma. PMID:27340408

  10. Informe del NCI y los CDC sobre el tabaco sin humo

    Cancer.gov

    El primer informe sobre el consumo mundial del tabaco sin humo y sus consecuencias en la salud pública reveló que más de 300 millones de personas en al menos 70 países usan estos productos dañinos.

  11. Bad Actors Criticality Assessment for Pipeline system

    NASA Astrophysics Data System (ADS)

    Nasir, Meseret; Chong, Kit wee; Osman, Sabtuni; Siaw Khur, Wee

    2015-04-01

    Failure of a pipeline system could bring huge economic loss. In order to mitigate such catastrophic loss, it is required to evaluate and rank the impact of each bad actor of the pipeline system. In this study, bad actors are known as the root causes or any potential factor leading to the system downtime. Fault Tree Analysis (FTA) is used to analyze the probability of occurrence for each bad actor. Bimbaum's Importance and criticality measure (BICM) is also employed to rank the impact of each bad actor on the pipeline system failure. The results demonstrate that internal corrosion; external corrosion and construction damage are critical and highly contribute to the pipeline system failure with 48.0%, 12.4% and 6.0% respectively. Thus, a minor improvement in internal corrosion; external corrosion and construction damage would bring significant changes in the pipeline system performance and reliability. These results could also be useful to develop efficient maintenance strategy by identifying the critical bad actors.

  12. Appia, Craig and the Actor: A New Look.

    ERIC Educational Resources Information Center

    Hubbard, Oliver F., Jr.

    Despite the amount of attention paid Adolphe Appia and Edward Gordon Craig, a misconception persists with regard to their ideas concerning the actor; namely, that Appia had the actor dominate all the elements of staging, and that Craig considered the actor less essential. However, to both, the actor was both essential and nonessential to the…

  13. ACToR - Aggregated Computational Toxicology Resource

    SciTech Connect

    Judson, Richard Richard, Ann; Dix, David; Houck, Keith; Elloumi, Fathi; Martin, Matthew; Cathey, Tommy; Transue, Thomas R.; Spencer, Richard; Wolf, Maritja

    2008-11-15

    ACToR (Aggregated Computational Toxicology Resource) is a database and set of software applications that bring into one central location many types and sources of data on environmental chemicals. Currently, the ACToR chemical database contains information on chemical structure, in vitro bioassays and in vivo toxicology assays derived from more than 150 sources including the U.S. Environmental Protection Agency (EPA), Centers for Disease Control (CDC), U.S. Food and Drug Administration (FDA), National Institutes of Health (NIH), state agencies, corresponding government agencies in Canada, Europe and Japan, universities, the World Health Organization (WHO) and non-governmental organizations (NGOs). At the EPA National Center for Computational Toxicology, ACToR helps manage large data sets being used in a high-throughput environmental chemical screening and prioritization program called ToxCast{sup TM}.

  14. Policy Actors: Doing Policy Work in Schools

    ERIC Educational Resources Information Center

    Ball, Stephen J.; Maguire, Meg; Braun, Annette; Hoskins, Kate

    2011-01-01

    This paper considers the "policy work" of teacher actors in schools. It focuses on the "problem of meaning" and offers a typology of roles and positions through which teachers engage with policy and with which policies get "enacted". It argues that "policy work" is made up of a set of complex and differentiated activities which involve both…

  15. Public Policies and Strategies of Actors

    ERIC Educational Resources Information Center

    Loiret, Pierre-Jean

    2011-01-01

    The synthesis "Public Policies and Strategies of Actors" concerns the same theme as Part 4 of the "Handbook of Distance Education" (Moore 2007), which deals with policies, administration, and management. Eleven articles illustrate the theme. Three articles are studies about the experience in France between 2000 and 2003 of the digital campuses.…

  16. Actor-Network Theory of Cosmopolitan Education

    ERIC Educational Resources Information Center

    Saito, Hiro

    2010-01-01

    In the past, philosophers discussed cosmopolitanism as a normative ideal of allegiance to humanity as a whole. A debate among social theorists, however, has examined cosmopolitanism as an incipient empirical phenomenon: an orientation of openness to foreign others and cultures. This paper introduces actor-network theory to elaborate the…

  17. Constructing Careers: Actor, Agent, and Author

    ERIC Educational Resources Information Center

    Savickas, Mark L.

    2011-01-01

    When individuals seek career counseling, they have stories to tell about their working lives. The aim of career construction theory is to be comprehensive in encouraging employment counselors to listen for a client's career story from the perspectives of actor, agent, and author. Taking multiple perspectives on career stories enables counselors to…

  18. Autoreporte de exposición a publicidad y promoción de tabaco en una cohorte de fumadores mexicanos: Antes y durante la publicación de la Ley General para el Control del tabaco en 2008

    PubMed Central

    Hernández, Rosaura Pérez; Thrasher, James F.; Bolaños, Rosibel Rodríguez; Gutiérrez, Inti Barrientos; Hernández, Norma A Ibañez

    2015-01-01

    Resumen Objetivo Determinar en población fumadora el nivel de exposición a la mercadotecnia por parte de la Industria Tabacalera (IT), a través de diferentes métodos de promocionar sus productos de tabaco, antes y durante la publicación de la Ley General para el Control del Tabaco (LGCT) en 2008. Material y métodos Estudio de cohorte en fumadores adultos (n=941 pre-LGCT y n=1051 post-LGCT) de cuatro ciudades mexicanas. Se realizaron análisis multivariados mediante modelos de ecuaciones de estimación generalizada (GEE). Resultados Se incremento el autoreporte de recepción de muestras gratis de cigarros (3.7% a 8.1%), ropa o artículos con marcas o logos (3.6% a 6.4%), haber visto información sobre eventos especiales (1.9% a 4.7%), y bares, antros y discos para mayores de edad (21.4% a 28%). Se observaron decrementos de publicidad en exteriores (54.7% a 47.2%). Conclusión Es necesaria una política integral con prohibiciones totales de la publicidad y promoción de los productos de tabaco que integre mayor vigilancia y sanciones para lograr la disminución y prevención del consumo de tabaco. PMID:22689158

  19. Pro-sociality without empathy

    PubMed Central

    Vasconcelos, Marco; Hollis, Karen; Nowbahari, Elise; Kacelnik, Alex

    2012-01-01

    Empathy, the capacity to recognize and share feelings experienced by another individual, is an important trait in humans, but is not the same as pro-sociality, the tendency to behave so as to benefit another individual. Given the importance of understanding empathy's evolutionary emergence, it is unsurprising that many studies attempt to find evidence for it in other species. To address the question of what should constitute evidence for empathy, we offer a critical comparison of two recent studies of rescuing behaviour that report similar phenomena but are interpreted very differently by their authors. In one of the studies, rescue behaviour in rats was interpreted as providing evidence for empathy, whereas in the other, rescue behaviour in ants was interpreted without reference to sharing of emotions. Evidence for empathy requires showing that actor individuals possess a representation of the receiver's emotional state and are driven by the psychological goal of improving its wellbeing. Proving psychological goal-directedness by current standards involves goal-devaluation and causal sensitivity protocols, which, in our view, have not been implemented in available publications. Empathy has profound significance not only for cognitive and behavioural sciences but also for philosophy and ethics and, in our view, remains unproven outside humans. PMID:22859561

  20. Pro-sociality without empathy.

    PubMed

    Vasconcelos, Marco; Hollis, Karen; Nowbahari, Elise; Kacelnik, Alex

    2012-12-23

    Empathy, the capacity to recognize and share feelings experienced by another individual, is an important trait in humans, but is not the same as pro-sociality, the tendency to behave so as to benefit another individual. Given the importance of understanding empathy's evolutionary emergence, it is unsurprising that many studies attempt to find evidence for it in other species. To address the question of what should constitute evidence for empathy, we offer a critical comparison of two recent studies of rescuing behaviour that report similar phenomena but are interpreted very differently by their authors. In one of the studies, rescue behaviour in rats was interpreted as providing evidence for empathy, whereas in the other, rescue behaviour in ants was interpreted without reference to sharing of emotions. Evidence for empathy requires showing that actor individuals possess a representation of the receiver's emotional state and are driven by the psychological goal of improving its wellbeing. Proving psychological goal-directedness by current standards involves goal-devaluation and causal sensitivity protocols, which, in our view, have not been implemented in available publications. Empathy has profound significance not only for cognitive and behavioural sciences but also for philosophy and ethics and, in our view, remains unproven outside humans. PMID:22859561

  1. Integrating actors into a simulation program: a primer.

    PubMed

    Pascucci, Robert C; Weinstock, Peter H; O'Connor, Brigid E; Fancy, Kristina M; Meyer, Elaine C

    2014-04-01

    We describe our more than 10 years' experience working with actors and provide a "how-to" guide to recruiting, auditioning, hiring, training, and mentoring actors for work as simulated patients in simulation programs. We contend that trained actors add great realism, richness, and depth to simulation-based training programs. The actors experience satisfaction from their contributions, and their skill and improvisational talent allow programs to offer ethical and relational training, customized to a wide range of practitioners and adapted across a variety of health care conversations. Such learning opportunities can directly address Accreditation Council for Graduate Medical Education core competencies in preparing capable, confident, and empathic health care practitioners. PMID:24096918

  2. Is It What You Do, or When You Do It? the Roles of Contingency and Similarity in Pro-Social Effects of Imitation

    ERIC Educational Resources Information Center

    Catmur, Caroline; Heyes, Cecilia

    2013-01-01

    Being imitated has a wide range of pro-social effects, but it is not clear how these effects are mediated. Naturalistic studies of the effects of being imitated have not established whether pro-social outcomes are due to the similarity and/or the contingency between the movements performed by the actor and those of the imitator. Similarity is…

  3. ACToR: Aggregated Computational Toxicology Resource (T)

    EPA Science Inventory

    The EPA Aggregated Computational Toxicology Resource (ACToR) is a set of databases compiling information on chemicals in the environment from a large number of public and in-house EPA sources. ACToR has 3 main goals: (1) The serve as a repository of public toxicology information ...

  4. Understanding the Employment of Actors. Research Division Report #3.

    ERIC Educational Resources Information Center

    National Endowment for the Arts, Washington, DC. Research Div.

    Focusing on actors' employment problems, part 1 of this report describes data collected by Actor's Equity primarily in terms of: (1) membership files; (2) the organization's contract department; (3) pension and welfare funds; and (4) employment statistics. Part 2 analyzes these data sets in relation to employment, unemployment, risk factors for…

  5. Teaching, Learning, and Leading: Preparing Teachers as Educational Policy Actors

    ERIC Educational Resources Information Center

    Heineke, Amy J.; Ryan, Ann Marie; Tocci, Charles

    2015-01-01

    Within the current federal, state, and local contexts of educational reform, teachers must be recognized as central actors in policy work, but rarely do we explicitly consider preparing teachers to become policy actors. Understanding these implications for teacher education, we investigate teacher candidates' learning of the complexity and…

  6. ProMat

    Energy Science and Technology Software Center (ESTSC)

    2008-06-12

    ProMAT is a software tool for statistically analyzing data from enzyme-linked immunosorbent assay microarray experiments. The software estimates standard curves, sample protein concentrations and their uncertainties for multiple assays. ProMAT generates a set of comprehensive figures for assessing results and diagnosing process quality. The tool is available for Windows or Mac, and is distributed as open-source Java and R code

  7. A false dichotomy? Mental illness and lone-actor terrorism.

    PubMed

    Corner, Emily; Gill, Paul

    2015-02-01

    We test whether significant differences in mental illness exist in a matched sample of lone- and group-based terrorists. We then test whether there are distinct behavioral differences between lone-actor terrorists with and without mental illness. We then stratify our sample across a range of diagnoses and again test whether significant differences exist. We conduct a series of bivariate, multivariate, and multinomial statistical tests using a unique dataset of 119 lone-actor terrorists and a matched sample of group-based terrorists. The odds of a lone-actor terrorist having a mental illness is 13.49 times higher than the odds of a group actor having a mental illness. Lone actors who were mentally ill were 18.07 times more likely to have a spouse or partner who was involved in a wider movement than those without a history of mental illness. Those with a mental illness were more likely to have a proximate upcoming life change, more likely to have been a recent victim of prejudice, and experienced proximate and chronic stress. The results identify behaviors and traits that security agencies can utilize to monitor and prevent lone-actor terrorism events. The correlated behaviors provide an image of how risk can crystalize within the individual offender and that our understanding of lone-actor terrorism should be multivariate in nature. PMID:25133916

  8. ACToR A Aggregated Computational Toxicology Resource

    EPA Science Inventory

    We are developing the ACToR system (Aggregated Computational Toxicology Resource) to serve as a repository for a variety of types of chemical, biological and toxicological data that can be used for predictive modeling of chemical toxicology.

  9. 29 CFR 570.125 - Actors and performers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... an actor or performer in motion pictures or theatrical productions, or in radio or television... definition will be helpful in determining whether a child qualifies as a “* * * performer in motion...

  10. Whose Journey Is It? A Critic's Plea to Actors.

    ERIC Educational Resources Information Center

    Lasser, Michael

    1999-01-01

    Laments the narcissism that the author sees in too many contemporary approaches to acting and directing. Argues that actors must focus on the world outside themselves, where the play and the audience most need them to be. (SR)

  11. Efficient model learning methods for actor-critic control.

    PubMed

    Grondman, Ivo; Vaandrager, Maarten; Buşoniu, Lucian; Babuska, Robert; Schuitema, Erik

    2012-06-01

    We propose two new actor-critic algorithms for reinforcement learning. Both algorithms use local linear regression (LLR) to learn approximations of the functions involved. A crucial feature of the algorithms is that they also learn a process model, and this, in combination with LLR, provides an efficient policy update for faster learning. The first algorithm uses a novel model-based update rule for the actor parameters. The second algorithm does not use an explicit actor but learns a reference model which represents a desired behavior, from which desired control actions can be calculated using the inverse of the learned process model. The two novel methods and a standard actor-critic algorithm are applied to the pendulum swing-up problem, in which the novel methods achieve faster learning than the standard algorithm. PMID:22156998

  12. ACToR A Aggregated Computational Toxicology Resource (S)

    EPA Science Inventory

    We are developing the ACToR system (Aggregated Computational Toxicology Resource) to serve as a repository for a variety of types of chemical, biological and toxicological data that can be used for predictive modeling of chemical toxicology.

  13. PRO-140 (Progenics).

    PubMed

    Poli, G

    2001-09-01

    PRO-140, a monoclonal antibody against the HIV coreceptor CCR5, is under investigation by Progenics and the Aaron Diamond AIDS Research Center (ADARC) as a potential treatment for HIV infection [211441], [286246], [286247]. Phase I/II trials were expected to commence during 2001 [395621], [409142], despite being initially planned for 2000 [322637], [361819], [365216], [375598], [408483]. In January 1998, ADARC and Progenics reported that the HIV binding site on the CCR5 coreceptor is distinct from betachemokine binding domains, which they claimed may allow for the development of therapeutics with fewer side effects [273391], 421256]. In vitro studies have shown PRO-140 potently blocked all of 17 primary HIV isolates that use CCR5 as a fusion coreceptor [342173]. In October 2000, Progenics was awarded an SBIR grant to fund a 2-year project exploring the breadth, potency and durability of PRO-140 therapy in laboratory and animal models of HIV infection. This project was a collaboration between Progenics, Weill Medical College of Cornell University and the Scripps Research Institute [385982]. In May 1999, the company entered into an agreement with Protein Design Labs (PDL) for the humanization by PDL of PRO-140 [325445]. In November 1997, Progenics was awarded a 600,000 dollars grant from the NIAID for the examination of new approaches to HIV vaccine design based on CCR5 [268407]. PMID:15965853

  14. TOXIRAE PRO PID

    EPA Science Inventory

    The ToxiRAE Pro PID measures total volatile organic compounds (VOCs) using a photoionization detector (PID). This sensor can be programmed to measure concentrations of a specified compound automatically and has a real time reading of VOC concentrations in parts per million (ppm) ...

  15. Transnational corporations as 'keystone actors' in marine ecosystems.

    PubMed

    Österblom, Henrik; Jouffray, Jean-Baptiste; Folke, Carl; Crona, Beatrice; Troell, Max; Merrie, Andrew; Rockström, Johan

    2015-01-01

    Keystone species have a disproportionate influence on the structure and function of ecosystems. Here we analyze whether a keystone-like pattern can be observed in the relationship between transnational corporations and marine ecosystems globally. We show how thirteen corporations control 11-16% of the global marine catch (9-13 million tons) and 19-40% of the largest and most valuable stocks, including species that play important roles in their respective ecosystem. They dominate all segments of seafood production, operate through an extensive global network of subsidiaries and are profoundly involved in fisheries and aquaculture decision-making. Based on our findings, we define these companies as keystone actors of the Anthropocene. The phenomenon of keystone actors represents an increasingly important feature of the human-dominated world. Sustainable leadership by keystone actors could result in cascading effects throughout the entire seafood industry and enable a critical transition towards improved management of marine living resources and ecosystems. PMID:26017777

  16. Two-actor conflict with time delay: A dynamical model

    NASA Astrophysics Data System (ADS)

    Qubbaj, Murad R.; Muneepeerakul, Rachata

    2012-11-01

    Recent mathematical dynamical models of the conflict between two different actors, be they nations, groups, or individuals, have been developed that are capable of predicting various outcomes depending on the chosen feedback strategies, initial conditions, and the previous states of the actors. In addition to these factors, this paper examines the effect of time delayed feedback on the conflict dynamics. Our analysis shows that under certain initial and feedback conditions, a stable neutral equilibrium of conflict may destabilize for some critical values of time delay, and the two actors may evolve to new emotional states. We investigate the results by constructing critical delay surfaces for different sets of parameters and analyzing results from numerical simulations. These results provide new insights regarding conflict and conflict resolution and may help planners in adjusting and assessing their strategic decisions.

  17. Actor Networks and the Division of Knowledge in the University.

    ERIC Educational Resources Information Center

    Busch, Lawrence

    This paper discusses the current division of knowledge at the college and university level, its historical roots, and the application of Actor Network Theory (ANT) to arrive at an explanation of the permanence of the current division of knowledge as well as what form a new division of knowledge might take. It finds fragmentation and disintegration…

  18. Researching the Habitus of Global Policy Actors in Education

    ERIC Educational Resources Information Center

    Lingard, Bob; Sellar, Sam; Baroutsis, Aspa

    2015-01-01

    This paper reprises the argument for the emergence of a global education policy field and then focuses on the shared habitus of global and national policy actors and technicians. It is argued that this shared habitus is constituted as a reflection of and a contribution to the creation of the global education policy field. Bourdieu's approach…

  19. Hugh Grant's Image Restoration Discourse: An Actor Apologizes.

    ERIC Educational Resources Information Center

    Benoit, William L.

    1997-01-01

    Examines the strategies used by actor Hugh Grant (in his appearances on talk shows) to help restore his reputation after he was arrested for lewd behavior with a prostitute. Uses this case as a springboard to contrast entertainment image repair with political and corporate image repair, arguing that important situational differences can be…

  20. Educational Judgment: Linking the Actor and the Spectator.

    ERIC Educational Resources Information Center

    Coulter, David; Wiens, John R.

    2002-01-01

    Recommends moving from debates between spectators and actors about knowledge and practice to discussions about how all educators can foster good judgment, outlining Aristotle's and Kant's accounts of judgment, which ultimately privilege spectators, and introducing Arendt's work. Arendt linked thinking and acting without privileging either in her…

  1. Children's Recognition of Plans in the Behavior of Other Actors.

    ERIC Educational Resources Information Center

    Walton, Marsha D.; Sedlak, Andrea J.

    An investigation of children's tendencies to infer planfulness from the behavior of other actors revealed systematic differences in the responses of kindergarten and second-grade children to questions about the motives, goals, and knowledge of story characters. Participating in the study were 13 boys and 13 girls attending public school (15…

  2. Lifelong Learning in the EU: Changing Conceptualisations, Actors, and Policies

    ERIC Educational Resources Information Center

    Volles, Nina

    2016-01-01

    This paper explores the changing conceptualisations, actors, and policies of lifelong learning (LLL) in the European Union (EU) from the time the topic first emerged and was promoted by international organisations in the 1960s. The author uses Kingdon's Multiple Streams Framework to analyse how the LLL discourse became an important part of the EU…

  3. VR/IS Lab Virtual Actor research overview

    SciTech Connect

    Shawver, D.M.; Stansfield, S.

    1995-06-22

    This overview presents current research at Sandia National Laboratories in the Virtual Reality and Intelligent Simulation Lab. Into an existing distributed VR environment which we have been developing, and which provides shared immersion for multiple users, we are adding virtual actor support. The virtual actor support we are adding to this environment is intended to provide semi-autonomous actors, with oversight and high-level guiding control by a director/user, and to allow the overall action to be driven by a scenario. We present an overview of the environment into which our virtual actors will be added in Section 3, and discuss the direction of the Virtual Actor research itself in Section 4. We will briefly review related work in Section 2. First however we need to place the research in the context of what motivates it. The motivation for our construction of this environment, and the line of research associated with it, is based on a long-term program of providing support, through simulation, for situational training, by which we mean a type of training in which students learn to handle multiple situations or scenarios. In these situations, the student may encounter events ranging from the routine occurance to the rare emergency. Indeed, the appeal of such training systems is that they could allow the student to experience and develop effective responses for situations they would otherwise have no opportunity to practice, until they happened to encounter an actual occurance. Examples of the type of students for this kind of training would be security forces or emergency response forces. An example of the type of training scenario we would like to support is given in Section 4.2.

  4. Balancing influence between actors in healthcare decision making

    PubMed Central

    2011-01-01

    Background Healthcare costs in most developed countries are not clearly linked to better patient and public health outcomes, but are rather associated with service delivery orientation. In the U.S. this has resulted in large variation in healthcare availability and use, increased cost, reduced employer participation in health insurance programs, and reduced overall population health outcomes. Recent U.S. healthcare reform legislation addresses only some of these issues. Other countries face similar healthcare issues. Discussion A major goal of healthcare is to enhance patient health outcomes. This objective is not realized in many countries because incentives and structures are currently not aligned for maximizing population health. The misalignment occurs because of the competing interests between "actors" in healthcare. In a simplified model these are individuals motivated to enhance their own health; enterprises (including a mix of nonprofit, for profit and government providers, payers, and suppliers, etc.) motivated by profit, political, organizational and other forces; and government which often acts in the conflicting roles of a healthcare payer and provider in addition to its role as the representative and protector of the people. An imbalance exists between the actors, due to the resources and information control of the enterprise and government actors relative to the individual and the public. Failure to use effective preventive interventions is perhaps the best example of the misalignment of incentives. We consider the current Pareto efficient balance between the actors in relation to the Pareto frontier, and show that a significant change in the healthcare market requires major changes in the utilities of the enterprise and government actors. Summary A variety of actions are necessary for maximizing population health within the constraints of available resources and the current balance between the actors. These actions include improved transparency of

  5. Teachers as Actors: The Implications of Acting on Physics Teaching

    NASA Astrophysics Data System (ADS)

    Milner-Bolotin, Marina

    2007-10-01

    In the spring of 2006, a rather unusual advertisement by the Centre of Teaching and Academic Growth at UBC (http://www.tag.ubc.ca) came to my attention. Faculty members were invited to take part in a workshop entitled "All the World's a Stage: Teachers as Actors," offered by a zoology instructor and an amateur actor, Greg Bole: Teaching can be seen as creating an interpersonal relationship and hence uses many of the same skills as acting. The investigation and use of acting skills in teacher preparation can allow a greater facility with diverse methods, increase skill at adapting to change in the classroom or lecture hall, and an increased ability to quickly form positive relationships with students. (Greg Bole: http://www.tag.ubc.ca/programs/series-detail.php?series_id=249 )

  6. Performance Analysis of an Actor-Based Distributed Simulation

    NASA Technical Reports Server (NTRS)

    Schoeffler, James D.

    1998-01-01

    Object-oriented design of simulation programs appears to be very attractive because of the natural association of components in the simulated system with objects. There is great potential in distributing the simulation across several computers for the purpose of parallel computation and its consequent handling of larger problems in less elapsed time. One approach to such a design is to use "actors", that is, active objects with their own thread of control. Because these objects execute concurrently, communication is via messages. This is in contrast to an object-oriented design using passive objects where communication between objects is via method calls (direct calls when they are in the same address space and remote procedure calls when they are in different address spaces or different machines). This paper describes a performance analysis program for the evaluation of a design for distributed simulations based upon actors.

  7. Extended Generalized Blockmodeling for Compound Communities and External Actors

    NASA Astrophysics Data System (ADS)

    Brendel, Radoslaw; Krawczyk, Henryk

    Some social communities evident their own unique internal structure. In this chapter, we consider social communities composed of several cohesive subgroups which we call compound communities. For such communities, an extended generalized blockmodeling is proposed, taking into account the structure of compound communities and their relations with external actors. Using the extension, the community protection approach is proposed and used in detection of spam directed toward an e-mail local society.

  8. When More Power Makes Actors Worse off: Turning a Profit in the American Economy

    ERIC Educational Resources Information Center

    Piskorski, Mikolaj Jan; Casciaro, Tiziana

    2006-01-01

    We propose a theory which predicts that an increase in an actor's relative power reduces the actor's rewards in high mutual dependence dyads. Our argument is based on the premise that higher relative power gives the more powerful actor a greater share of surplus, but it also reduces dyadic exchange frequency, which lowers the expected magnitude of…

  9. A Low-cost System for Generating Near-realistic Virtual Actors

    NASA Astrophysics Data System (ADS)

    Afifi, Mahmoud; Hussain, Khaled F.; Ibrahim, Hosny M.; Omar, Nagwa M.

    2015-06-01

    Generating virtual actors is one of the most challenging fields in computer graphics. The reconstruction of a realistic virtual actor has been paid attention by the academic research and the film industry to generate human-like virtual actors. Many movies were acted by human-like virtual actors, where the audience cannot distinguish between real and virtual actors. The synthesis of realistic virtual actors is considered a complex process. Many techniques are used to generate a realistic virtual actor; however they usually require expensive hardware equipment. In this paper, a low-cost system that generates near-realistic virtual actors is presented. The facial features of the real actor are blended with a virtual head that is attached to the actor's body. Comparing with other techniques that generate virtual actors, the proposed system is considered a low-cost system that requires only one camera that records the scene without using any expensive hardware equipment. The results of our system show that the system generates good near-realistic virtual actors that can be used on many applications.

  10. Cognitively Central Actors and Their Personal Networks in an Energy Efficiency Training Program

    ERIC Educational Resources Information Center

    Hytönen, Kaisa; Palonen, Tuire; Hakkarainen, Kai

    2014-01-01

    This article aims to examine cognitively central actors and their personal networks in the emerging field of energy efficiency. Cognitively central actors are frequently sought for professional advice by other actors and, therefore, they are positioned in the middle of a social network. They often are important knowledge resources, especially in…

  11. Breaking into the Business: Experiences of Actors with Disabilities in the Entertainment Industry

    ERIC Educational Resources Information Center

    Raynor, Olivia; Hayward, Katharine

    2009-01-01

    The pursuit of an acting career is a difficult one for anybody. However, studies have yet to factor how disability affects casting opportunities. This study describes the employment of actors with disabilities, along with the unique barriers they encounter in the audition and casting process. Actors with disabilities from the Screen Actors Guild…

  12. Who Needs What? Some Thoughts on the Possibility of Using Psychology in Actor Training.

    ERIC Educational Resources Information Center

    Vulova, Marina

    2001-01-01

    Contends that the aim of professional actor training is to reveal and develop an actor's individuality. Proposes that the responsibility of drama teachers is to lead training in such away that students feel accepted, understood, and respected. Proposes that psychodrama is the most appropriate method for student and professional actors' personal…

  13. The angiotensin converting enzyme inhibitory tripeptides Ile-Pro-Pro and Val-Pro-Pro show increasing permeabilities with increasing physiological relevance of absorption models.

    PubMed

    Foltz, Martin; Cerstiaens, Anja; van Meensel, Ans; Mols, Raf; van der Pijl, Pieter C; Duchateau, Guus S M J E; Augustijns, Patrick

    2008-08-01

    Transepithelial transport of the ACE inhibitory peptides Ile-Pro-Pro and Val-Pro-Pro was studied in different models of absorption. Apparent permeability (P(app)) values for absorptive transport across Caco-2 monolayers were 1.0+/-0.9 x 10(-8) (Ile-Pro-Pro) and 0.5+/-0.1 x 10(-8)cms(-1) (Val-Pro-Pro). Ex vivo transport across jejunal segments in the Ussing chamber was 5-times (Ile-Pro-Pro) to 10-times (Val-Pro-Pro) higher with no significant differences (p>0.05) observed between both peptides. The peptidase inhibitor bestatin increased permeability for the absorptive direction for Ile-Pro-Pro by twofold. Neither a transepithelial pH gradient nor increased apical tripeptide concentration nor longitudinal localization of the intestinal segment influenced P(app) in the ex vivo experiments. Val-Pro-Pro transport across Peyer's patches, however, was 4-times higher (P(app)=21.0+/-9.3 x10(-8)cms(-1)) as compared to duodenum (P(app)=4.8+/-1.4 x 10(-8)cms(-1)). In the in situ perfusion experiments P(app) values varied greatly among different animals ranging from 0.5 to 24.0 x10(-8)cms(-1) (Ile-Pro-Pro) and from 1.0 to 15.6 x 10(-8)cms(-1) (Val-Pro-Pro). In summary, Caco-2 and ex vivo absorption models differ considerably regarding their peptide permeability. The in situ model seems to be less appropriate because of the observed large variability in peptide permeability. The results of this study demonstrate that the ACE inhibitory peptides Ile-Pro-Pro and Val-Pro-Pro are absorbed partially undegraded. PMID:18490081

  14. Sharing, caring, and surveilling: an actor-partner interdependence model examination of Facebook relational maintenance strategies.

    PubMed

    McEwan, Bree

    2013-12-01

    Abstract Relational maintenance is connected to high quality friendships. Friendship maintenance behaviors may occur online via social networking sites. This study utilized an Actor-Partner Interdependence Model to examine how Facebook maintenance and surveillance affect friendship quality. Bryant and Marmo's (2012) Facebook maintenance scale was evaluated, revealing two factors: sharing and caring. Facebook surveillance was also measured. For friendship satisfaction and liking, significant positive actor and partner effects emerged for caring; significant negative actor, partner, and interaction effects emerged for sharing; and significant positive actor effects emerged for surveillance. For friendship closeness, significant positive actor effects emerged for caring and surveillance. PMID:23962125

  15. Production of intoxication states by actors: perception by lay listeners.

    PubMed

    Hollien, H; DeJong, G; Martin, C A

    1998-11-01

    The effects of ingesting ethanol have been shown to be somewhat variable in humans; there appear to be but few universals. Yet, questions about intoxication often are asked by law enforcement personnel (especially relative to DUI), clinicians and various individuals in social settings. A key question: Is it possible to determine if a person is intoxicated by observing them in some manner? A closely associated one: Can speech be used for that purpose? Two of the many issues related to the second of these questions involve the possibility that (1) speakers, especially actors, can effectively mimic the speech of intoxicated individuals, and (2) they may be able to volitionally reduce any speech degradation which results from intoxication. The approach used to test these two questions tasked auditors to determine if these simulations were possible. To this end, young, healthy actors chosen on the basis of a large number of selection criteria were asked to produce several types of controlled utterances (1) during a learning phase, (2) when sober, (3) at three simulated levels of intoxication (mildly, legally and severely drunk), (4) during actual, and parallel, levels of intoxication, and (5) at the highest intoxication level attained but when attempting to sound completely sober. Two aural-perceptual studies were conducted; both involved counterbalanced ABX procedures where each subject was paired with him/herself. Listeners were normally hearing university students drawn from undergraduate phonetics and linguistics courses. In the first study, they rated the actors as being more intoxicated--when they actually were sober but simulating drunkenness--88% more often than when they actually were intoxicated. In the second study, they were judged as sounding less inebriated when attempting to sound sober (than they actually were) 61% of the time. These relationships would appear to impact a number of situations; one of special importance would be the detection of

  16. Backpack Smarts from A Pro

    MedlinePlus

    ... page: https://medlineplus.gov/news/fullstory_160665.html Backpack Smarts From a Pro Overloaded carryalls injure thousands ... SATURDAY, Aug. 27, 2016 (HealthDay News) -- Ill-fitting backpacks may put school children at risk for muscle ...

  17. Macro-actor execution on multilevel data-driven architectures

    SciTech Connect

    Gaudiot, J.L.; Najjar, W.

    1988-12-31

    The data-flow model of computation brings to multiprocessors high programmability at the expense of increased overhead. Applying the model at a higher level leads to better performance but also introduces loss of parallelism. We demonstrate here syntax directed program decomposition methods for the creation of large macro-actors in numerical algorithms. In order to alleviate some of the problems introduced by the lower resolution interpretation, we describe a multi-level of resolution and analyze the requirements for its actual hardware and software integration.

  18. Construal level and free will beliefs shape perceptions of actors' proximal and distal intent.

    PubMed

    Plaks, Jason E; Robinson, Jeffrey S

    2015-01-01

    Two components of lay observers' calculus of moral judgment are proximal intent (the actor's mind is focused on performing the action) and distal intent (the actor's mind is focused on the broader goal). What causes observers to prioritize one form of intent over the other? The authors observed whether construal level (Studies 1-2) and beliefs about free will (Studies 3-4) would influence participants' sensitivity to the actor's proximal vs. distal intent. In four studies, participants read scenarios in which the actor's proximal and distal intent were independently manipulated. In Study 1, when only distal intent was present in the actor's mind, participants rated the psychologically distant actor more responsible than the psychologically near actor. In Study 2, when only distal intent was in the actor's mind, participants with a chronic high level of action identification rated the actor more responsible than did those with a low level of action identification. In both studies, when only proximal intent was in the actor's mind, construal level did not predict judgments of responsibility. In Study 3, when only proximal intent was present in the actor's mind, the more participants believed in free will, the more they rated the actor responsible. When only distal intent was in the actor's mind, free will belief did not influence ratings of responsibility. In Study 4, the same pattern emerged when free will/determinism beliefs were manipulated and the actor performed a positive (life-saving) act. The authors discuss how these results shed new light on the literatures on moral reasoning and psycho-legal theory. PMID:26106352

  19. Construal level and free will beliefs shape perceptions of actors' proximal and distal intent

    PubMed Central

    Plaks, Jason E.; Robinson, Jeffrey S.

    2015-01-01

    Two components of lay observers' calculus of moral judgment are proximal intent (the actor's mind is focused on performing the action) and distal intent (the actor's mind is focused on the broader goal). What causes observers to prioritize one form of intent over the other? The authors observed whether construal level (Studies 1–2) and beliefs about free will (Studies 3–4) would influence participants' sensitivity to the actor's proximal vs. distal intent. In four studies, participants read scenarios in which the actor's proximal and distal intent were independently manipulated. In Study 1, when only distal intent was present in the actor's mind, participants rated the psychologically distant actor more responsible than the psychologically near actor. In Study 2, when only distal intent was in the actor's mind, participants with a chronic high level of action identification rated the actor more responsible than did those with a low level of action identification. In both studies, when only proximal intent was in the actor's mind, construal level did not predict judgments of responsibility. In Study 3, when only proximal intent was present in the actor's mind, the more participants believed in free will, the more they rated the actor responsible. When only distal intent was in the actor's mind, free will belief did not influence ratings of responsibility. In Study 4, the same pattern emerged when free will/determinism beliefs were manipulated and the actor performed a positive (life-saving) act. The authors discuss how these results shed new light on the literatures on moral reasoning and psycho-legal theory. PMID:26106352

  20. What about the "actor's formant" in actresses' voices?

    PubMed

    Master, Suely; De Biase, Noemi Grigolleto; Madureira, Sandra

    2012-05-01

    Spectrographic analysis of male actors' voices showed a cluster, the "actor's formant" (AF), which is related to the perception of good and projected voice quality. To date, similar phenomena have not been described in the voices of actresses. Therefore, the objective of the current investigation was to compare actresses' and nonactresses' voices through acoustic analysis to verify the existence of the "AF" cluster or the strategies used to produce the performing voice. Thirty actresses and 30 nonactresses volunteered as subjects in the present study. All subjects read a 40-second text at both habitual and loud levels. Praat (v.5.1) was then used to analyze equivalent sound pressure level (Leq), speaking fundamental frequency (SFF), and in the long-term average spectrum window, the difference between the amplitude level of the fundamental frequency and first formant (L1-L0), the spectral tilt (alpha ratio), and the amplitude and frequency of the "AF" region. Significant differences between the groups, in both levels, were observed for SFF and L1-L0, with actresses presenting lower values. There were no significant differences between groups for Leq or alpha ratio at either level. There was no evidence of an "AF" cluster in the actresses' voices. Voice projection for this group of actresses seemed to be mainly a result of a laryngeal setting instead of vocal tract resonances. PMID:21376530

  1. Understanding Health Information Seeking from an Actor-Centric Perspective

    PubMed Central

    Batchelor, Simon; Waldman, Linda; Bloom, Gerry; Rasheed, Sabrina; Scott, Nigel; Ahmed, Tanvir; Uz Zaman Khan, Nazib; Sharmin, Tamanna

    2015-01-01

    This paper presents a conceptual approach for discussing health information seeking among poor households in Africa and Asia. This approach is part of a larger research endeavor aimed at understanding how health systems are adapting; with possibilities and constraints emerging. These health systems can be found in a context of the changing relationships between states, markets and civil society in low and middle income countries. The paper starts from an understanding of the health sector as a “health knowledge economy”, organized to provide people with access to knowledge and advice. The use of the term “health knowledge economy” draws attention to the ways the health sector is part of a broader knowledge economy changing the way individuals and households obtain and use specialist information. The paper integrates an actor centric approach with the theory of planned behavior. It seeks to identify the actors engaged in the health knowledge economy as a precursor to longer term studies on the uptake of innovations integrating health services with mobile phones, commonly designated as mHealth, contributing to an understanding of the potential vulnerabilities of poor people, and highlighting possible dangers if providers of health information and advice are strongly influenced by interest groups. PMID:26184275

  2. Song Perception by Professional Singers and Actors: An MEG Study.

    PubMed

    Rosslau, Ken; Herholz, Sibylle C; Knief, Arne; Ortmann, Magdalene; Deuster, Dirk; Schmidt, Claus-Michael; Zehnhoff-Dinnesen, Antoinetteam; Pantev, Christo; Dobel, Christian

    2016-01-01

    The cortical correlates of speech and music perception are essentially overlapping, and the specific effects of different types of training on these networks remain unknown. We compared two groups of vocally trained professionals for music and speech, singers and actors, using recited and sung rhyme sequences from German art songs with semantic and/ or prosodic/melodic violations (i.e. violations of pitch) of the last word, in order to measure the evoked activation in a magnetoencephalographic (MEG) experiment. MEG data confirmed the existence of intertwined networks for the sung and spoken modality in an early time window after word violation. In essence for this early response, higher activity was measured after melodic/prosodic than semantic violations in predominantly right temporal areas. For singers as well as for actors, modality-specific effects were evident in predominantly left-temporal lateralized activity after semantic expectancy violations in the spoken modality, and right-dominant temporal activity in response to melodic violations in the sung modality. As an indication of a special group-dependent audiation process, higher neuronal activity for singers appeared in a late time window in right temporal and left parietal areas, both after the recited and the sung sequences. PMID:26863437

  3. Understanding Health Information Seeking from an Actor-Centric Perspective.

    PubMed

    Batchelor, Simon; Waldman, Linda; Bloom, Gerry; Rasheed, Sabrina; Scott, Nigel; Ahmed, Tanvir; Khan, Nazib Uz Zaman; Sharmin, Tamanna

    2015-07-01

    This paper presents a conceptual approach for discussing health information seeking among poor households in Africa and Asia. This approach is part of a larger research endeavor aimed at understanding how health systems are adapting; with possibilities and constraints emerging. These health systems can be found in a context of the changing relationships between states, markets and civil society in low and middle income countries. The paper starts from an understanding of the health sector as a "health knowledge economy", organized to provide people with access to knowledge and advice. The use of the term "health knowledge economy" draws attention to the ways the health sector is part of a broader knowledge economy changing the way individuals and households obtain and use specialist information. The paper integrates an actor centric approach with the theory of planned behavior. It seeks to identify the actors engaged in the health knowledge economy as a precursor to longer term studies on the uptake of innovations integrating health services with mobile phones, commonly designated as mHealth, contributing to an understanding of the potential vulnerabilities of poor people, and highlighting possible dangers if providers of health information and advice are strongly influenced by interest groups. PMID:26184275

  4. Song Perception by Professional Singers and Actors: An MEG Study

    PubMed Central

    Rosslau, Ken; Herholz, Sibylle C.; Knief, Arne; Ortmann, Magdalene; Deuster, Dirk; Schmidt, Claus-Michael; Zehnhoff-Dinnesen, Antoinetteam; Pantev, Christo; Dobel, Christian

    2016-01-01

    The cortical correlates of speech and music perception are essentially overlapping, and the specific effects of different types of training on these networks remain unknown. We compared two groups of vocally trained professionals for music and speech, singers and actors, using recited and sung rhyme sequences from German art songs with semantic and/ or prosodic/melodic violations (i.e. violations of pitch) of the last word, in order to measure the evoked activation in a magnetoencephalographic (MEG) experiment. MEG data confirmed the existence of intertwined networks for the sung and spoken modality in an early time window after word violation. In essence for this early response, higher activity was measured after melodic/prosodic than semantic violations in predominantly right temporal areas. For singers as well as for actors, modality-specific effects were evident in predominantly left-temporal lateralized activity after semantic expectancy violations in the spoken modality, and right-dominant temporal activity in response to melodic violations in the sung modality. As an indication of a special group-dependent audiation process, higher neuronal activity for singers appeared in a late time window in right temporal and left parietal areas, both after the recited and the sung sequences. PMID:26863437

  5. Action adaptation during natural unfolding social scenes influences action recognition and inferences made about actor beliefs.

    PubMed

    Keefe, Bruce D; Wincenciak, Joanna; Jellema, Tjeerd; Ward, James W; Barraclough, Nick E

    2016-07-01

    When observing another individual's actions, we can both recognize their actions and infer their beliefs concerning the physical and social environment. The extent to which visual adaptation influences action recognition and conceptually later stages of processing involved in deriving the belief state of the actor remains unknown. To explore this we used virtual reality (life-size photorealistic actors presented in stereoscopic three dimensions) to see how visual adaptation influences the perception of individuals in naturally unfolding social scenes at increasingly higher levels of action understanding. We presented scenes in which one actor picked up boxes (of varying number and weight), after which a second actor picked up a single box. Adaptation to the first actor's behavior systematically changed perception of the second actor. Aftereffects increased with the duration of the first actor's behavior, declined exponentially over time, and were independent of view direction. Inferences about the second actor's expectation of box weight were also distorted by adaptation to the first actor. Distortions in action recognition and actor expectations did not, however, extend across different actions, indicating that adaptation is not acting at an action-independent abstract level but rather at an action-dependent level. We conclude that although adaptation influences more complex inferences about belief states of individuals, this is likely to be a result of adaptation at an earlier action recognition stage rather than adaptation operating at a higher, more abstract level in mentalizing or simulation systems. PMID:27472496

  6. Structural analysis of the Tabaco anticline, Cerrejón open-cast coal mine, Colombia, South America

    NASA Astrophysics Data System (ADS)

    Cardozo, Néstor; Montes, Camilo; Marín, Dora; Gutierrez, Iván; Palencia, Alejandro

    2016-06-01

    The Tabaco anticline is a 15 km long, south plunging, east-vergent anticline in northern Colombia, close to the transpressional collisional margin between the Caribbean and South American plates. In the Cerrejón open-cast coal mine, systematic mapping of coal seams in the middle to upper Paleocene Cerrejón Formation has yielded an exceptional dataset consisting of 10 horizontal slices (sea level to 90 m elevation, regularly spaced at 10 m intervals) through the anticline. Coal seams and fault traces in these slices are used to construct a 3D model of the anticline. This 3D model shows tighter folds within lower coal seams, NW-vergent thrusts and related folds on the gentler western limb, and strike-slip faults on the steeper eastern limb. Fault slip-tendency analysis is used to infer that these two faulting styles resulted from two different stress fields: an earlier one consistent with thrusting and uplift of the Perijá range, and a later one consistent with strike-slip faulting (Oca, Ranchería and Samán faults). Our preferred interpretation is that the anticline developed its eastern vergence during the early stages (late Paleocene-early Eocene) of tilting of the Santa Marta massif. Later NW-vergent thrusting on the western limb (early to middle Eocene) was related to western propagation of the Perijá thrust system. These results contribute to the understanding of the structural evolution of the area. They are also a good example of the complex interplay between detachment folding, thrusting, and strike-slip faulting during the growth of a km-size fold in a transpressive setting.

  7. Structural analysis of the Tabaco anticline, Cerrejón open-cast coal mine, Colombia, South America

    NASA Astrophysics Data System (ADS)

    Cardozo, Néstor; Montes, Camilo; Marín, Dora; Gutierrez, Iván; Palencia, Alejandro

    2016-06-01

    The Tabaco anticline is a 15 km long, south plunging, east-vergent anticline in northern Colombia, close to the transpressional collisional margin between the Caribbean and South American plates. In the Cerrejón open-cast coal mine, systematic mapping of coal seams in the middle to upper Paleocene Cerrejón Formation has yielded an exceptional dataset consisting of 10 horizontal slices (sea level to 90 m elevation, regularly spaced at 10 m intervals) through the anticline. Coal seams and fault traces in these slices are used to construct a 3D model of the anticline. This 3D model shows tighter folds within lower coal seams, NW-vergent thrusts and related folds on the gentler western limb, and strike-slip faults on the steeper eastern limb. Fault slip-tendency analysis is used to infer that these two faulting styles resulted from two different stress fields: an earlier one consistent with thrusting and uplift of the Perijá range, and a later one consistent with strike-slip faulting (Oca, Ranchería and Samán faults). Our preferred interpretation is that the anticline developed its eastern vergence during the early stages (late Paleocene-early Eocene) of tilting of the Santa Marta massif. Later NW-vergent thrusting on the western limb (early to middle Eocene) was related to western propagation of the Perijá thrust system. These results contribute to the understanding of the structural evolution of the area. They are also a good example of the complex interplay between detachment folding, thrusting, and strike-slip faulting during the growth of a km-size fold in a transpressive setting.

  8. Mesenchymal Stem Cells after Polytrauma: Actor and Target

    PubMed Central

    Wiegner, Rebecca; Lampl, Lorenz; Brenner, Rolf E.

    2016-01-01

    Mesenchymal stem cells (MSCs) are multipotent cells that are considered indispensable in regeneration processes after tissue trauma. MSCs are recruited to damaged areas via several chemoattractant pathways where they function as “actors” in the healing process by the secretion of manifold pro- and anti-inflammatory, antimicrobial, pro- and anticoagulatory, and trophic/angiogenic factors, but also by proliferation and differentiation into the required cells. On the other hand, MSCs represent “targets” during the pathophysiological conditions after severe trauma, when excessively generated inflammatory mediators, complement activation factors, and damage- and pathogen-associated molecular patterns challenge MSCs and alter their functionality. This in turn leads to complement opsonization, lysis, clearance by macrophages, and reduced migratory and regenerative abilities which culminate in impaired tissue repair. We summarize relevant cellular and signaling mechanisms and provide an up-to-date overview about promising future therapeutic MSC strategies in the context of severe tissue trauma. PMID:27340408

  9. The actor as context for social judgments: effects of prior impressions and stereotypes.

    PubMed

    Stewart, T L; Doan, K A; Gingrich, B E; Smith, E R

    1998-11-01

    Three experiments identified conditions under which trait judgments made about a behavior were more likely to influence later judgments of the behavior. In Experiment 1, participants made trait judgments about numerous behaviors presented with photos of actors. Some behaviors were repeated, paired with the same or a different actor. All repeated behaviors were judged faster than new behaviors. Facilitation was greatest when repeated behaviors were paired with the same actor, suggesting greater influence of prior judgments in this condition. Experiments 2 and 3 replicated this effect, and the pattern of response times (RTs) suggested a stronger association between the actor and behavior when a prior impression of the actor had been formed (Experiment 2) and when the behavior was stereotypic of the actor's group (Experiment 3). Level of prejudice moderated RT patterns in Experiment 3. Implications for context effects, the nature of trait inferences, and stereotype change are discussed. PMID:9866181

  10. Politics, class actors, and health sector reform in Brazil and Venezuela.

    PubMed

    Mahmood, Qamar; Muntaner, Carles

    2013-03-01

    Universal access to healthcare has assumed renewed importance in global health discourse, along with a focus on strengthening health systems. These developments are taking place in the backdrop of concerted efforts to advocate moving away from vertical, disease-based approaches to tackling health problems. While this approach to addressing public health problems is a step in the right direction, there is still insufficient emphasis on understanding the socio-political context of health systems. Reforms to strengthen health systems and achieve universal access to healthcare should be cognizant of the importance of the socio-political context, especially state-society relations. That context determines the nature and trajectory of reforms promoting universality or any pro-equity change. Brazil and Venezuela in recent years have made progress in developing healthcare systems that aim to achieve universal access. These achievements are noteworthy given that, historically, both countries had a long tradition of healthcare systems which were highly privatized and geared towards access to healthcare for a small segment of the population while the majority was excluded. These achievements are also remarkable since they took place in an era of neoliberalism when many states, even those with universally-based healthcare systems, were moving in the opposite direction. We analyze the socio-political context in each of these countries and look specifically at how the changing state-society relations resulted in health being constitutionally recognized as a social right. We describe the challenges that each faced in developing and implementing healthcare systems embracing universality. Our contention is that achieving the principle of universality in healthcare systems is less of a technical matter and more a political project. It involves opposition from the socially conservative elements in the society. Navigation to achieve this goal requires a political strategy that

  11. ProC: Process Coordinator

    NASA Astrophysics Data System (ADS)

    Hovest, Wolfgang; Knoche, Jörg; Hell, Reinhard; Doerl, Uwe; Riller, Thomas; Matthai, Frank; Ensslin, Torsten; Rachen, Jörg; Robbers, Georg; Adorf, Hans-Martin; Reinecke, Martin; Bartelmann, Matthias

    2016-01-01

    ProC (short for Process Coordinator) is a versatile workflow engine that allows the user to build, run and manage workflows with just a few clicks. It automatically documents every processing step, making every modification to data reproducible. ProC provides a graphical user interface for constructing complex data processing workflows out of a given set of computer programs. The user can, for example, specify that only data products which are affected by a change in the input data are updated selectively, avoiding unnecessary computations. The ProC suite is flexible and satisfies basic needs of data processing centers that have to be able to restructure their data processing along with the development of a project.

  12. Using actor network theory to understand network centric healthcare operations.

    PubMed

    Wickramasinghe, Nilmini; Bali, Rajeev K; Tatnall, Arthur

    2007-01-01

    The adoption and diffusion of e-health and the application of ICT in healthcare is being heralded as the panacea with both European and US governments making e-health a priority on their agendas. In this context, a model of networkcentric healthcare operations has been proffered as the best way to maximise the benefits of ICT use in healthcare. We suggest that, before we can move forward and realise such a state, it is vital to examine the critical issues, likely barriers and facilitators and, most importantly, the critical success factors. To do this however, we need an appropriate cognitive lens through which we can capture all the complexities of healthcare dynamics. In this paper we suggest why Actor Network Theory (ANT) should be this lens. PMID:18048305

  13. Ship Finds and Their Management as Actor Network

    NASA Astrophysics Data System (ADS)

    Tuddenham, David Berg

    2012-12-01

    Ship finds in Norwegian waters that are more than 100 years old came under the jurisdiction of the Cultural Heritage Management (CHM) in 1963, when section 12a of the Norwegian Cultural Heritage Act was implemented. As a consequence, a functional division between land and sea was created where management objects receive different values depending on whether or not they belong to a ship. The objective of this paper is to review Norwegian CHM underwater policy, and discuss the creation of a new management object and its borders with the introduction of a section on ship finds specifically focusing on Actor Network Theory. It is argued that the understanding of the ship find and its belongings can not be understood as something based on inherent qualities to the management object. Instead this paper proposes to comprehend the ship find as a phenomenon held together within a heterogeneous network.

  14. Role of Actors and Gender Factor in Disaster Management

    NASA Astrophysics Data System (ADS)

    Gundogdu, Oguz; Isik, Ozden; Ozcep, Ferhat; Goksu, Goksel

    2014-05-01

    In Turkey, the discussions in the modern sense about disaster management begun after the 1992 Erzincan and the 1995 Dinar earthquakes, faulting in terms of features and effects. These earthquakes are "Urban Earthquakes'' with effects and faulting charectristics, and have led to radical changes in terms of disaster and disaster management. Disaster Management, to become a science in the world, but with the 1999 Izmit and Duzce earthquakes in Turkey has begun to take seriously on the agenda. Firstly, such as Civil Defense and Red Crescent organizations, by transforming its own, have entered into a new organizing effort. By these earthquakes, NGO's have contributed the search-rescue efforts in the field and to the process of normalization of life. Because "the authority and responsibilities" of NGO's could not be determined, and could not be in planning and scenario studies, we faced the problems. Thus, to the citizens of our country-specific "voluntary" has not benefited enough from the property. The most important development in disaster management in 2009, the Disaster and Emergency Management Presidency (AFAD) has been the establishment. However, in terms of coordination and accreditation to the target point has been reached yet. Another important issue in disaster management (need to be addressed along with disaster actors) is the role of women in disasters. After the Golcuk Earthquake, successful field works of women and women's victimization has attracted attention in two different directions. Gender-sensitive policies should be noted by the all disaster actors due to the importance of the mitigation, and these policies should take place in laws, regulations and planning.

  15. Reassembling the Social - An Introduction to Actor-Network-Theory

    NASA Astrophysics Data System (ADS)

    Latour, Bruno

    2005-09-01

    Reassembling the Social is a fundamental challenge from one of the world's leading social theorists to how we understand society and the 'social'. Bruno Latour's contention is that the world 'social' as used by Social Scientists has become laden with assumptions to the point where it has become misnomer. When the adjective is applied to a phenomenon, it is used to indicate a stabilized state of affairs, a bundle of ties that in due course may be used to account for another phenomenon. But Latour also finds the word used as if it described a type of material, in a comparable way to an adjective such as 'wooden' or 'steely'. Rather than simply indicating what is already assembled together, it is now used in a way that makes assumptions about the nature of what is assembled. It has become a word that designates two distinct things: a process of assembling: and a type of material, distinct from others. Latour shows why 'the social' cannot be thought of as a kind of material or domain, and disputes attempts to provide a 'social explanation' of other states of affairs. While these attempts have been productive (and probably necessary) in the past, the very success of the social sciences mean that they are largely no longer so. At the present stage it is no longer possible to inspect the precise constituents entering the social domain. Latour returns to the original meaning of 'the social' to redefine the notion and allow it to trace connections again. It will then be possible to resume the traditional goal of the social sciences, but using more refined tools. Drawing on his extensive work examining the 'assemblages' of nature, Latour finds it necessary to scrutinize thoroughly the exact content of what is assembled under the umbrella of Society. This approach, a 'sociology of associations' has become known as Actor-Network-Theory, and this book is an essential introduction both for those seeking to understand Actor-Network-Theory, or the ideas of one of its most

  16. Managing the Bologna Process at the European Level: Institution and Actor Dynamics

    ERIC Educational Resources Information Center

    Lazetic, Predrag

    2010-01-01

    This article analyses the work of the Bologna Follow Up Group as the main institution of the Bologna Process and the perceptions of the policy actors involved concerning the character of the process in terms of its functioning in contrast to similar multi-level multi-actor European processes, its modes of communication and consensus seeking, as…

  17. Reading Educational Reform with Actor Network Theory: Fluid Spaces, Otherings, and Ambivalences

    ERIC Educational Resources Information Center

    Fenwick, Tara

    2011-01-01

    In considering two extended examples of educational reform efforts, this discussion traces relations that become visible through analytic approaches associated with actor-network theory (ANT). The strategy here is to present multiple readings of the two examples. The first reading adopts an ANT approach to follow ways that all actors--human and…

  18. Commercial Actors and the Governing of Education: The Case of Academy School Sponsors in England

    ERIC Educational Resources Information Center

    Papanastasiou, Natalie

    2013-01-01

    This article explores the ways in which commercial actors are operating in state education by focusing on the case study of England's academies policy. First of all the discussion outlines the development of academies over time and the way in which the policy has provided opportunities for private actors to become involved in the state…

  19. Nonhumans Unbound: Actor-Network Theory and the Reconsideration of "Things" in Educational Foundations

    ERIC Educational Resources Information Center

    Waltz, Scott B.

    2006-01-01

    The aim of this paper is to call attention to the missing discourse of non-humans as social actors in the Social Foundations of Education. The paper outlines three common figuring metaphors that impede the adoption of such a theoretical discourse and shows how Actor-Network Theory (ANT), more recently developed in the nascent field of Science and…

  20. West Side Silence: Producing "West Side Story" with Deaf and Hearing Actors.

    ERIC Educational Resources Information Center

    Brewer, Diane

    2002-01-01

    Details a collaborative production of "West Side Story" with hearing actors from MacMurray College and deaf actors from the Illinois School for the Deaf. Explores some of the practical dilemmas encountered as the distinctions between the Deaf and hearing communities were negotiated. Explains that the show explored the ways in which sign language…

  1. Corner Office: ProQuest's Marty Kahn

    ERIC Educational Resources Information Center

    Fialkoff, Francine; Oder, Norman

    2009-01-01

    In a scant three years at ProQuest, Marty Kahn, CEO, has moved a company coming out of a financial morass back onto solid ground. He came on board after the purchase of ProQuest Information and Learning by the (mostly) privately owned Cambridge Information Group in late 2006 and the merger of ProQuest and CSA to form ProQuest CSA. (It's now just…

  2. CREMA-D: Crowd-sourced Emotional Multimodal Actors Dataset

    PubMed Central

    Cao, Houwei; Cooper, David G.; Keutmann, Michael K.; Gur, Ruben C.; Nenkova, Ani; Verma, Ragini

    2014-01-01

    People convey their emotional state in their face and voice. We present an audio-visual data set uniquely suited for the study of multi-modal emotion expression and perception. The data set consists of facial and vocal emotional expressions in sentences spoken in a range of basic emotional states (happy, sad, anger, fear, disgust, and neutral). 7,442 clips of 91 actors with diverse ethnic backgrounds were rated by multiple raters in three modalities: audio, visual, and audio-visual. Categorical emotion labels and real-value intensity values for the perceived emotion were collected using crowd-sourcing from 2,443 raters. The human recognition of intended emotion for the audio-only, visual-only, and audio-visual data are 40.9%, 58.2% and 63.6% respectively. Recognition rates are highest for neutral, followed by happy, anger, disgust, fear, and sad. Average intensity levels of emotion are rated highest for visual-only perception. The accurate recognition of disgust and fear requires simultaneous audio-visual cues, while anger and happiness can be well recognized based on evidence from a single modality. The large dataset we introduce can be used to probe other questions concerning the audio-visual perception of emotion. PMID:25653738

  3. BNP and NT-proBNP Test

    MedlinePlus

    ... Peptides Formal name: B-type Natriuretic Peptide; N-terminal pro b-type Natriuretic Peptide Related tests: Cardiac ... for B-type natriuretic peptide (BNP) or N-terminal pro b-type natriuretic peptide (NT-proBNP) is ...

  4. Two routes to actorhood: lexicalized potency to act and identification of the actor role.

    PubMed

    Frenzel, Sabine; Schlesewsky, Matthias; Bornkessel-Schlesewsky, Ina

    2015-01-01

    The inference of causality is a crucial cognitive ability and language processing is no exception: recent research suggests that, across different languages, the human language comprehension system attempts to identify the primary causer of the state of affairs described (the "actor") quickly and unambiguously (Bornkessel-Schlesewsky and Schlesewsky, 2009). This identification can take place verb-independently based on certain prominence cues (e.g., case, word order, animacy). Here, we present two experiments demonstrating that actor potential is also encoded at the level of individual nouns (a king is a better actor than a beggar). Experiment 1 collected ratings for 180 German nouns on 12 scales defined by adjective oppositions and deemed relevant for actorhood potential. By means of structural equation modeling, an actor potential (ACT) value was calculated for each noun. Experiment 2, an event-related potential study, embedded nouns from Experiment 1 in verb-final sentences, in which they were either actors or non-actors. N400 amplitude increased with decreasing ACT values and this modulation was larger for highly frequent nouns and for actor versus non-actor nouns. We argue that potency to act is lexically encoded for individual nouns and, since it modulates the N400 even for non-actor participants, it should be viewed as a property that modulates ease of lexical access (akin, for example, to lexical frequency). We conclude that two separate dimensions of actorhood computation are crucial to language comprehension: an experience-based, lexically encoded (bottom-up) representation of actorhood potential, and a prominence-based, computational mechanism for calculating goodness-of-fit to the actor role in a particular (top-down) sentence context. PMID:25688217

  5. ProMAT: protein microarray analysis tool

    SciTech Connect

    White, Amanda M.; Daly, Don S.; Varnum, Susan M.; Anderson, Kevin K.; Bollinger, Nikki; Zangar, Richard C.

    2006-04-04

    Summary: ProMAT is a software tool for statistically analyzing data from ELISA microarray experiments. The software estimates standard curves, sample protein concentrations and their uncertainties for multiple assays. ProMAT generates a set of comprehensive figures for assessing results and diagnosing process quality. The tool is available for Windows or Mac, and is distributed as open-source Java and R code. Availability: ProMAT is available at http://www.pnl.gov/statistics/ProMAT. ProMAT requires Java version 1.5.0 and R version 1.9.1 (or more recent versions) which are distributed with the tool.

  6. Hacia el consumo informado de tabaco en México: efecto de las advertencias con pictogramas en población fumadora

    PubMed Central

    Thrasher, James F; Pérez-Hernández, Rosaura; Arillo-Santillán, Edna; Barrientos-Gutiérrez, Inti

    2015-01-01

    Resumen Objetivo Evaluar el efecto de las advertencias sanitarias (AS) con pictogramas en las cajetillas de tabaco en adultos fumadores. Material y métodos Cohorte de fumadores con representatividad poblacional de siete ciudades mexi canas, antes (2010) y después (2011) de la implementación de AS con pictogramas (ASP). Para determinar el cambio en las variables sobre el impacto cognitivo y conductual de las advertencias, se estimaron modelos bivariados y ajustados de ecuaciones de estimación generalizada. En el Segundo levantamiento (2011), se estimaron modelos para determiner los factores que se asocian con el reporte de recordar cada advertencia que había entrado al mercado, además de los factores asociados con el autorreporte del impacto de cada advertencia vigente. Resultados Se observaron incrementos importantes de 2010 a 2011 en los conocimientos sobre los riesgos de fumar, los componentes tóxicos del tabaco y el número telefónico para recibir consejos sobre dejar de fumar. La recordación e impacto de las primeras advertencias con pictogramas parecen ser amplios y equitativos a través de la población fumadora. En comparación con 2010, un mayor nivel de ex fumadores entrevistados en 2011 reportaron que las advertencias habían influido mucho en dejar de fumar (RM=2.44, 95% IC 1.27–4.72). Conclusiones Las AS con pictogramas han logrado un impacto importante en el conocimiento y conducta, información relevante para la población y en tomadores de decisiones. PMID:22689162

  7. Force-stabilizing synergies in motor tasks involving two actors.

    PubMed

    Solnik, Stanislaw; Reschechtko, Sasha; Wu, Yen-Hsun; Zatsiorsky, Vladimir M; Latash, Mark L

    2015-10-01

    We investigated the ability of two persons to produce force-stabilizing synergies in accurate multi-finger force production tasks under visual feedback on the total force only. The subjects produced a time profile of total force (the sum of two hand forces in one-person tasks and the sum of two subject forces in two-person tasks) consisting of a ramp-up, steady-state, and ramp-down segments; the steady-state segment was interrupted in the middle by a quick force pulse. Analyses of the structure of inter-trial finger force variance, motor equivalence, anticipatory synergy adjustments (ASAs), and the unintentional drift of the sharing pattern were performed. The two-person performance was characterized by a dramatically higher amount of inter-trial variance that did not affect total force, higher finger force deviations that did not affect total force (motor equivalent deviations), shorter ASAs, and larger drift of the sharing pattern. The rate of sharing pattern drift correlated with the initial disparity between the forces produced by the two persons (or two hands). The drift accelerated following the quick force pulse. Our observations show that sensory information on the task-specific performance variable is sufficient for the organization of performance-stabilizing synergies. They suggest, however, that two actors are less likely to follow a single optimization criterion as compared to a single performer. The presence of ASAs in the two-person condition might reflect fidgeting by one or both of the subjects. We discuss the characteristics of the drift in the sharing pattern as reflections of different characteristic times of motion within the subspaces that affect and do not affect salient performance variables. PMID:26105756

  8. Deterring Asymmetric Threats from Sub-State Actors

    SciTech Connect

    Homsy, R V

    2002-01-31

    Deterrence means preventing another's actions by influencing their decisionmaking process. Nuclear deterrence was successfully accomplished during the Cold War by holding the adversary's valuable assets at risk by targeting them with nuclear weapons, a policy known as mutually assured destruction (MAD). In this case neither player attacks the other, because the ultimate outcome is self-destruction. Deterrence based upon MAD is largely ineffective against sub-state actors who may have few if any assets, the location of which may be unknown. Furthermore, the threat of destroying their assets may only serve to strengthen their motivation to do more stealthy violence, the threat being interpreted as a taunt. The key to establishing deterrence is understanding the adversary's decision process, starting with the factors upon which decisions are made, called decision attributes. Asymmetric threats are assumed to involve chemical, biological, radiological, or nuclear (CBRN) weapons. So, the key decision attributes here are concerned with the acquisition and use of CBRN weapons. We have identified the following five countermeasure objectives for establishing deterrence: (1) Reduce access to CBRN weapons, expertise, materials, and equipment; (2) Make CBRN weapons difficult to use; (3) Reduce the effectiveness of CBRN weapons; (4) Increase the likelihood of being caught acquiring and using CBRN weapons; and (5) Establish a policy of retribution for acquiring and using CBRN weapons. It should be emphasized that an adversary's perception toward these objectives is most important in affecting their decisionmaking. Of course each adversary will respond differently toward these countermeasures, depending upon their motivations, objectives, preferences, resources, and willingness to gamble. Motivation of violence is defined as the fundamental cause or driving force; absent which the intent to do violence no longer exists. Correct understanding of motivations requires adapting your

  9. Bombing alone: tracing the motivations and antecedent behaviors of lone-actor terrorists,.

    PubMed

    Gill, Paul; Horgan, John; Deckert, Paige

    2014-03-01

    This article analyzes the sociodemographic network characteristics and antecedent behaviors of 119 lone-actor terrorists. This marks a departure from existing analyses by largely focusing upon behavioral aspects of each offender. This article also examines whether lone-actor terrorists differ based on their ideologies or network connectivity. The analysis leads to seven conclusions. There was no uniform profile identified. In the time leading up to most lone-actor terrorist events, other people generally knew about the offender's grievance, extremist ideology, views, and/or intent to engage in violence. A wide range of activities and experiences preceded lone actors' plots or events. Many but not all lone-actor terrorists were socially isolated. Lone-actor terrorists regularly engaged in a detectable and observable range of activities with a wider pressure group, social movement, or terrorist organization. Lone-actor terrorist events were rarely sudden and impulsive. There were distinguishable behavioral differences between subgroups. The implications for policy conclude this article. PMID:24313297

  10. Two routes to actorhood: lexicalized potency to act and identification of the actor role

    PubMed Central

    Frenzel, Sabine; Schlesewsky, Matthias; Bornkessel-Schlesewsky, Ina

    2015-01-01

    The inference of causality is a crucial cognitive ability and language processing is no exception: recent research suggests that, across different languages, the human language comprehension system attempts to identify the primary causer of the state of affairs described (the “actor”) quickly and unambiguously (Bornkessel-Schlesewsky and Schlesewsky, 2009). This identification can take place verb-independently based on certain prominence cues (e.g., case, word order, animacy). Here, we present two experiments demonstrating that actor potential is also encoded at the level of individual nouns (a king is a better actor than a beggar). Experiment 1 collected ratings for 180 German nouns on 12 scales defined by adjective oppositions and deemed relevant for actorhood potential. By means of structural equation modeling, an actor potential (ACT) value was calculated for each noun. Experiment 2, an event-related potential study, embedded nouns from Experiment 1 in verb-final sentences, in which they were either actors or non-actors. N400 amplitude increased with decreasing ACT values and this modulation was larger for highly frequent nouns and for actor versus non-actor nouns. We argue that potency to act is lexically encoded for individual nouns and, since it modulates the N400 even for non-actor participants, it should be viewed as a property that modulates ease of lexical access (akin, for example, to lexical frequency). We conclude that two separate dimensions of actorhood computation are crucial to language comprehension: an experience-based, lexically encoded (bottom–up) representation of actorhood potential, and a prominence-based, computational mechanism for calculating goodness-of-fit to the actor role in a particular (top–down) sentence context. PMID:25688217

  11. Inferring the Size of a Goal Object from an Actor's Grasping Movement in 6- and 9-Month-Old Infants

    ERIC Educational Resources Information Center

    Daum, Moritz M.; Vuori, Maria T.; Prinz, Wolfgang; Aschersleben, Gisa

    2009-01-01

    The present study applied a preferential looking paradigm to test whether 6- and 9-month old infants are able to infer the size of a goal object from an actor's grasping movement. The target object was a cup with the handle rotated either towards or away from the actor. In two experiments, infants saw the video of an actor's grasping movement…

  12. Vocal range and intensity in actors: a studio versus stage comparison.

    PubMed

    Emerich, Kate A; Titze, Ingo R; Svec, Jan G; Popolo, Peter S; Logan, Gary

    2005-03-01

    A voice range profile (VRP) was obtained from each of eight professional actors and compared with two speech range profiles (SRPs). One speech profile was obtained during the dramatic reading of a scene in the laboratory and the other during a performance on stage in a professional theater. The objective was to determine the pitch and loudness ranges used by the actors in speech relative to the VRP. The principal question of interest was whether the actors stayed within the center of the VRP, or whether they tended to drift toward the boundaries of intensity and frequency. A second question was whether the performance within the laboratory accurately reflects that of a stage performance. The results suggest that some subjects tend to exceed the center of the VRP during the stage performance. It is hypothesized that these actors may stress their vocal mechanism during performance and are more likely candidates for vocal injury. PMID:15766852

  13. Two-factor theory, the actor-critic model, and conditioned avoidance.

    PubMed

    Maia, Tiago V

    2010-02-01

    Two-factor theory (Mowrer, 1947, 1951, 1956) remains one of the most influential theories of avoidance, but it is at odds with empirical findings that demonstrate sustained avoidance responding in situations in which the theory predicts that the response should extinguish. This article shows that the well-known actor-critic model seamlessly addresses the problems with two-factor theory, while simultaneously being consistent with the core ideas that underlie that theory. More specifically, the article shows that (1) the actor-critic model bears striking similarities to two-factor theory and explains all of the empirical phenomena that two-factor theory explains, in much the same way, and (2) there are subtle but important differences between the actor-critic model and two-factor theory, which result in the actor-critic model predicting the persistence of avoidance responses that is found empirically. PMID:20065349

  14. Modeling and training emotional talking faces of virtual actors in synthetic movies

    NASA Astrophysics Data System (ADS)

    Karunaratne, Savant; Yan, Hong

    2000-05-01

    This paper presents an overview of a virtual actor system composed of several subsystems designed to automate some of these animation tasks. Our emphasis is on the facial animation of virtual actors. The paper specifically details the situations processor component of the framework, which is a major building block in the automatic virtual actor system. An expert system using a fuzzy knowledge-based control system is used to realize the automated system. Fuzzy linguistic rules are used to train virtual actors to know the appropriate emotions and gestures to use in different situations of a synthetic movie, the higher level parameters of which are provided by human directors. Theories of emotion, personality, dialogue, and acting, as well as empirical evidence is incorporated into our framework and knowledge bases to produce promising results.

  15. Time-delay effects on dynamics of a two-actor conflict model

    NASA Astrophysics Data System (ADS)

    Rojas-Pacheco, A.; Obregón-Quintana, B.; Liebovitch, L. S.; Guzmán-Vargas, L.

    2013-02-01

    We present a study of time-delay effects on a two-actor conflict model based on nonlinear differential equations. The state of each actor depends on its own state in isolation, its previous state, its inertia to change, the positive or negative feedback and a time delay in the state of the other actor. We use both theoretical and numerical approaches to characterize the evolution of the system for several values of time delays. We find that, under particular conditions, a time delay leads to the appearance of oscillations in the states of the actors. Besides, phase portraits for the trajectories are presented to illustrate the evolution of the system for different time delays. Finally, we discuss our results in the context of social conflict models.

  16. The Relation of Pro-Sociality to Self-Esteem: The Mediational Role of Quality of Friendships.

    PubMed

    Zuffianò, Antonio; Eisenberg, Nancy; Alessandri, Guido; Luengo Kanacri, Bernadette Paula; Pastorelli, Concetta; Milioni, Michela; Caprara, Gian Vittorio

    2016-02-01

    The present longitudinal study examined the role of quality of friendship in mediating the relation of pro-sociality to self-esteem over time. Participants were 424 Italian young adults (56% females) assessed at two waves (M(age) = 21.1 at Time 1; M(age) = 25 at Time 2). An autoregressive cross-lagged panel model was used to test the mediational model. Self- and friend-report measures of pro-sociality, quality of friendship, and self-esteem were included in the analyses. Results were in line with the hypothesized paths, with quality of friendship mediating the relation of pro-sociality to later self-esteem above and beyond its high stability. Self-esteem, in turn, predicted pro-sociality 4 years later. Overall, the present findings support the potential benefits of behaving pro-socially for an actor in terms of increased perceived self-worth and also expand previous work by outlining the specific mediational role of the quality of friendships. The theoretical and practical implications of these results are discussed. PMID:25234333

  17. Neuroimaging of the joint Simon effect with believed biological and non-biological co-actors

    PubMed Central

    Wen, Tanya; Hsieh, Shulan

    2015-01-01

    Performing a task alone or together with another agent can produce different outcomes. The current study used event-related functional magnetic resonance imaging (fMRI) to investigate the neural underpinnings when participants performed a Go/Nogo task alone or complementarily with another co-actor (unseen), whom was believed to be another human or a computer. During both complementary tasks, reaction time data suggested that participants integrated the potential action of their co-actor in their own action planning. Compared to the single-actor task, increased parietal and precentral activity during complementary tasks as shown in the fMRI data further suggested representation of the co-actor’s response. The superior frontal gyrus of the medial prefrontal cortex was differentially activated in the human co-actor condition compared to the computer co-actor condition. The medial prefrontal cortex, involved thinking about the beliefs and intentions of other people, possibly reflects a social-cognitive aspect or self-other discrimination during the joint task when believing a biological co-actor is present. Our results suggest that action co-representation can occur even offline with any agent type given a priori information that they are co-acting; however, additional regions are recruited when participants believe they are task-sharing with another human. PMID:26388760

  18. False recollection of the role played by an actor in an event.

    PubMed

    Kersten, Alan W; Earles, Julie L; Upshaw, Christin

    2013-11-01

    Two experiments demonstrated that eyewitnesses more frequently associate an actor with the actions of another person when those two people had appeared together in the same event, rather than in different events. This greater likelihood of binding an actor with the actions of another person from the same event was associated with high-confidence recognition judgments and "remember" responses in a remember-know task, suggesting that viewing an actor together with the actions of another person led participants to falsely recollect having seen that actor perform those actions. An analysis of age differences provided evidence that familiarity also contributed to false recognition independently of a false-recollection mechanism. In particular, older adults were more likely than young adults to falsely recognize a novel conjunction of a familiar actor and action, regardless of whether that actor and action were from the same or from different events. Older adults' elevated rate of false recognition was associated with intermediate confidence levels, suggesting that it stemmed from increased reliance on familiarity rather than from false recollection. The implications of these results are discussed for theories of conjunction errors in memory and of unconscious transference in eyewitness testimony. PMID:23722927

  19. False recollection of the role played by an actor in an event

    PubMed Central

    Earles, Julie L.; Upshaw, Christin

    2013-01-01

    Two experiments demonstrated that eyewitnesses more frequently associate an actor with the actions of another person when those two people had appeared together in the same event, rather than in different events. This greater likelihood of binding an actor with the actions of another person from the same event was associated with high-confidence recognition judgments and “remember” responses in a remember–know task, suggesting that viewing an actor together with the actions of another person led participants to falsely recollect having seen that actor perform those actions. An analysis of age differences provided evidence that familiarity also contributed to false recognition independently of a false-recollection mechanism. In particular, older adults were more likely than young adults to falsely recognize a novel conjunction of a familiar actor and action, regardless of whether that actor and action were from the same or from different events. Older adults’ elevated rate of false recognition was associated with intermediate confidence levels, suggesting that it stemmed from increased reliance on familiarity rather than from false recollection. The implications of these results are discussed for theories of conjunction errors in memory and of unconscious transference in eyewitness testimony. PMID:23722927

  20. Getting acquainted: Actor and partner effects of attachment and temperament on young children's peer behavior.

    PubMed

    McElwain, Nancy L; Holland, Ashley S; Engle, Jennifer M; Ogolsky, Brian G

    2014-06-01

    Guided by a dyadic view of children's peer behavior, this study assessed actor and partner effects of attachment security and temperament on young children's behavior with an unfamiliar peer. At 33 months of age, child-mother attachment security was assessed via a modified Strange Situation procedure, and parents reported on child temperament (anger proneness and social fearfulness). At 39 months, same-sex children (N = 114, 58 girls) were randomly paired, and child dyads were observed during 3 laboratory visits occurring over 1 month. Actor-partner interdependence models, tested via multilevel modeling, revealed that actor security, partner anger proneness, and acquaintanceship (e.g., initial vs. later visits) combined to predict child behavior. Actor security predicted more responsiveness to the new peer partner at the initial visit, regardless of partner anger proneness. Actor security continued to predict responsiveness at the 2nd and 3rd visits when partner anger was low, but these associations were nonsignificant when partner anger was high. Actor security also predicted a less controlling assertiveness style at the initial visit when partner anger proneness was high, yet this association was nonsignificant by the final visit. The findings shed light on the dynamic nature of young children's peer behavior and indicate that attachment security is related to behavior in expected ways during initial interactions with a new peer, but may change as children become acquainted. PMID:24635647

  1. Characteristics of pornography film actors: self-report versus perceptions of college students.

    PubMed

    Griffith, James D; Hayworth, Michelle; Adams, Lea T; Mitchell, Sharon; Hart, Christian

    2013-05-01

    The assumed characteristics of individuals in the adult entertainment industry have been used to advocate positions for and against pornography. Although prior studies have investigated perceptions of porn actors, no data on the actual characteristics of this group exist. The present study compared the self-reports of 105 male and 177 female porn actors to the perceptions of 399 college students on childhood sexual abuse (CSA), self-esteem, work and non-work sexual behaviors, and safe sex issues. College students were asked to identify the characteristics associated with either a male or female porn star. College students provided underestimates for both female and male porn actors on self-esteem, age of first intercourse, lifetime number of partners outside of work, ideal experience in a romantic partner, concerns regarding sexually transmitted diseases (STDs), enjoyment of sex, and condom use during a first time sexual encounter, but overestimated earnings. Additional differences among male porn stars included an underestimate of the number of partners at work. For female porn stars, college students underestimated their enjoyment of work, the probability of catching an STD, and having unprotected sex. Although there were no significant differences on perceived rates of childhood abuse of porn actors, the incidence of CSA among the porn actor participants were within the ranges of the general population. The majority of college student stereotypes were not supported regarding the perceptions of porn actors. These findings were discussed within the context of attributing unfounded characteristics of individuals to an entire industry. PMID:23179237

  2. Bombing Alone: Tracing the Motivations and Antecedent Behaviors of Lone-Actor Terrorists*,†,‡

    PubMed Central

    Gill, Paul; Horgan, John; Deckert, Paige

    2014-01-01

    This article analyzes the sociodemographic network characteristics and antecedent behaviors of 119 lone-actor terrorists. This marks a departure from existing analyses by largely focusing upon behavioral aspects of each offender. This article also examines whether lone-actor terrorists differ based on their ideologies or network connectivity. The analysis leads to seven conclusions. There was no uniform profile identified. In the time leading up to most lone-actor terrorist events, other people generally knew about the offender’s grievance, extremist ideology, views, and/or intent to engage in violence. A wide range of activities and experiences preceded lone actors’ plots or events. Many but not all lone-actor terrorists were socially isolated. Lone-actor terrorists regularly engaged in a detectable and observable range of activities with a wider pressure group, social movement, or terrorist organization. Lone-actor terrorist events were rarely sudden and impulsive. There were distinguishable behavioral differences between subgroups. The implications for policy conclude this article. PMID:24313297

  3. Airway hyperresponsiveness; smooth muscle as the principal actor.

    PubMed

    Lauzon, Anne-Marie; Martin, James G

    2016-01-01

    Airway hyperresponsiveness (AHR) is a defining characteristic of asthma that refers to the capacity of the airways to undergo exaggerated narrowing in response to stimuli that do not result in comparable degrees of airway narrowing in healthy subjects. Airway smooth muscle (ASM) contraction mediates airway narrowing, but it remains uncertain as to whether the smooth muscle is intrinsically altered in asthmatic subjects or is responding abnormally as a result of the milieu in which it sits. ASM in the trachea or major bronchi does not differ in its contractile characteristics in asthmatics, but the more pertinent peripheral airways await complete exploration. The mass of ASM is increased in many but not all asthmatics and therefore cannot be a unifying hypothesis for AHR, although when increased in mass it may contribute to AHR. The inability of a deep breath to reverse or prevent bronchial narrowing in asthma may reflect an intrinsic difference in the mechanisms that lead to softening of contracted ASM when subjected to stretch. Cytokines such as interleukin-13 and tumor necrosis factor-α promote a more contractile ASM phenotype. The composition and increased stiffness of the matrix in which ASM is embedded promotes a more proliferative and pro-inflammatory ASM phenotype, but the expected dedifferentiation and loss of contractility have not been shown. Airway epithelium may drive ASM proliferation and/or molecular remodeling in ways that may lead to AHR. In conclusion, AHR is likely multifactorial in origin, reflecting the plasticity of ASM properties in the inflammatory environment of the asthmatic airway. PMID:26998246

  4. Airway hyperresponsiveness; smooth muscle as the principal actor

    PubMed Central

    Lauzon, Anne-Marie; Martin, James G.

    2016-01-01

    Airway hyperresponsiveness (AHR) is a defining characteristic of asthma that refers to the capacity of the airways to undergo exaggerated narrowing in response to stimuli that do not result in comparable degrees of airway narrowing in healthy subjects. Airway smooth muscle (ASM) contraction mediates airway narrowing, but it remains uncertain as to whether the smooth muscle is intrinsically altered in asthmatic subjects or is responding abnormally as a result of the milieu in which it sits. ASM in the trachea or major bronchi does not differ in its contractile characteristics in asthmatics, but the more pertinent peripheral airways await complete exploration. The mass of ASM is increased in many but not all asthmatics and therefore cannot be a unifying hypothesis for AHR, although when increased in mass it may contribute to AHR. The inability of a deep breath to reverse or prevent bronchial narrowing in asthma may reflect an intrinsic difference in the mechanisms that lead to softening of contracted ASM when subjected to stretch. Cytokines such as interleukin-13 and tumor necrosis factor-α promote a more contractile ASM phenotype. The composition and increased stiffness of the matrix in which ASM is embedded promotes a more proliferative and pro-inflammatory ASM phenotype, but the expected dedifferentiation and loss of contractility have not been shown. Airway epithelium may drive ASM proliferation and/or molecular remodeling in ways that may lead to AHR. In conclusion, AHR is likely multifactorial in origin, reflecting the plasticity of ASM properties in the inflammatory environment of the asthmatic airway. PMID:26998246

  5. Not My Problem: Vicarious Conflict Adaptation with Human and Virtual Co-actors

    PubMed Central

    Spapé, Michiel M.; Ravaja, Niklas

    2016-01-01

    The Simon effect refers to an incompatibility between stimulus and response locations resulting in a conflict situation and, consequently, slower responses. Like other conflict effects, it is commonly reduced after repetitions, suggesting an executive control ability, which flexibly rewires cognitive processing and adapts to conflict. Interestingly, conflict is not necessarily individually defined: the Social Simon effect refers to a scenario where two people who share a task show a conflict effect where a single person does not. Recent studies showed these observations might converge into what could be called vicarious conflict adaptation, with evidence indicating that observing someone else's conflict may subsequently reduce one's own. While plausible, there is reason for doubt: both the social aspect of the Simon Effect, and the degree to which executive control accounts for the conflict adaptation effect, have become foci of debate in recent studies. Here, we present two experiments that were designed to test the social dimension of the effect by varying the social relationship between the actor and the co-actor. In Experiment 1, participants performed a conflict task with a virtual co-actor, while the actor-observer relationship was manipulated as a function of the similarity between response modalities. In Experiment 2, the same task was performed both with a virtual and with a human co-actor, while heart-rate measurements were taken to measure the impact of observed conflict on autonomous activity. While both experiments replicated the interpersonal conflict adaptation effects, neither showed evidence of the critical social dimension. We consider the findings as demonstrating that vicarious conflict adaptation does not rely on the social relationship between the actor and co-actor. PMID:27199839

  6. Not My Problem: Vicarious Conflict Adaptation with Human and Virtual Co-actors.

    PubMed

    Spapé, Michiel M; Ravaja, Niklas

    2016-01-01

    The Simon effect refers to an incompatibility between stimulus and response locations resulting in a conflict situation and, consequently, slower responses. Like other conflict effects, it is commonly reduced after repetitions, suggesting an executive control ability, which flexibly rewires cognitive processing and adapts to conflict. Interestingly, conflict is not necessarily individually defined: the Social Simon effect refers to a scenario where two people who share a task show a conflict effect where a single person does not. Recent studies showed these observations might converge into what could be called vicarious conflict adaptation, with evidence indicating that observing someone else's conflict may subsequently reduce one's own. While plausible, there is reason for doubt: both the social aspect of the Simon Effect, and the degree to which executive control accounts for the conflict adaptation effect, have become foci of debate in recent studies. Here, we present two experiments that were designed to test the social dimension of the effect by varying the social relationship between the actor and the co-actor. In Experiment 1, participants performed a conflict task with a virtual co-actor, while the actor-observer relationship was manipulated as a function of the similarity between response modalities. In Experiment 2, the same task was performed both with a virtual and with a human co-actor, while heart-rate measurements were taken to measure the impact of observed conflict on autonomous activity. While both experiments replicated the interpersonal conflict adaptation effects, neither showed evidence of the critical social dimension. We consider the findings as demonstrating that vicarious conflict adaptation does not rely on the social relationship between the actor and co-actor. PMID:27199839

  7. Integrated Programs and Pro-Environmental Behaviour

    ERIC Educational Resources Information Center

    Smith, Tiffany

    2008-01-01

    Research suggested that "nature experience as an education method played a role in developing environmental value and attitudes, and was influential in pro-environmental behaviour." Few of these studies however, assessed the long-term influences of outdoor education experiences on participants' pro-environmental behaviour. The Outward Bound Canada…

  8. Conformational Plasticity of proNGF

    PubMed Central

    Paoletti, Francesca; Malerba, Francesca; Kelly, Geoff; Noinville, Sylvie; Lamba, Doriano; Cattaneo, Antonino; Pastore, Annalisa

    2011-01-01

    Nerve Growth Factor is an essential protein that supports neuronal survival during development and influences neuronal function throughout adulthood, both in the central and peripheral nervous system. The unprocessed precursor of NGF, proNGF, seems to be endowed with biological functions distinct from those of the mature protein, such as chaperone-like activities and apoptotic and/or neurotrophic properties. We have previously suggested, based on Small Angle X-ray Scattering data, that recombinant murine proNGF has features typical of an intrinsically unfolded protein. Using complementary biophysical techniques, we show here new evidence that clarifies and widens this hypothesis through a detailed comparison of the structural properties of NGF and proNGF. Our data provide direct information about the dynamic properties of the pro-peptide and indicate that proNGF assumes in solution a compact globular conformation. The N-terminal pro-peptide extension influences the chemical environment of the mature protein and protects the protein from proteolytic digestion. Accordingly, we observe that unfolding of proNGF involves a two-steps mechanism. The distinct structural properties of proNGF as compared to NGF agree with and rationalise a different functional role of the precursor. PMID:21818348

  9. Representing Micro-Macro Linkages by Actor-Based Dynamic Network Models

    PubMed Central

    Snijders, Tom A.B.; Steglich, Christian E.G.

    2014-01-01

    Stochastic actor-based models for network dynamics have the primary aim of statistical inference about processes of network change, but may be regarded as a kind of agent-based models. Similar to many other agent-based models, they are based on local rules for actor behavior. Different from many other agent-based models, by including elements of generalized linear statistical models they aim to be realistic detailed representations of network dynamics in empirical data sets. Statistical parallels to micro-macro considerations can be found in the estimation of parameters determining local actor behavior from empirical data, and the assessment of goodness of fit from the correspondence with network-level descriptives. This article studies several network-level consequences of dynamic actor-based models applied to represent cross-sectional network data. Two examples illustrate how network-level characteristics can be obtained as emergent features implied by micro-specifications of actor-based models. PMID:25960578

  10. Emotional labor actors: a latent profile analysis of emotional labor strategies.

    PubMed

    Gabriel, Allison S; Daniels, Michael A; Diefendorff, James M; Greguras, Gary J

    2015-05-01

    Research on emotional labor focuses on how employees utilize 2 main regulation strategies-surface acting (i.e., faking one's felt emotions) and deep acting (i.e., attempting to feel required emotions)-to adhere to emotional expectations of their jobs. To date, researchers largely have considered how each strategy functions to predict outcomes in isolation. However, this variable-centered perspective ignores the possibility that there are subpopulations of employees who may differ in their combined use of surface and deep acting. To address this issue, we conducted 2 studies that examined surface acting and deep acting from a person-centered perspective. Using latent profile analysis, we identified 5 emotional labor profiles-non-actors, low actors, surface actors, deep actors, and regulators-and found that these actor profiles were distinguished by several emotional labor antecedents (positive affectivity, negative affectivity, display rules, customer orientation, and emotion demands-abilities fit) and differentially predicted employee outcomes (emotional exhaustion, job satisfaction, and felt inauthenticity). Our results reveal new insights into the nature of emotion regulation in emotional labor contexts and how different employees may characteristically use distinct combinations of emotion regulation strategies to manage their emotional expressions at work. PMID:25068812

  11. Pro-Anorexia and Pro-Recovery Photo Sharing: A Tale of Two Warring Tribes

    PubMed Central

    Yom-Tov, Elad; Weber, Ingmar; Crain, Steven P

    2012-01-01

    Background There is widespread use of the Internet to promote anorexia as a lifestyle choice. Pro-anorexia content can be harmful for people affected or at risk of having anorexia. That movement is actively engaged in sharing photos on social networks such as Flickr. Objective To study the characteristics of the online communities engaged in disseminating content that encourages eating disorders (known as “pro-anorexia”) and to investigate if the posting of such content is discouraged by the posting of recovery-oriented content. Methods The extraction of pro-anorexia and pro-recovery photographs from the photo sharing site Flickr pertaining to 242,710 photos from 491 users and analyzing four separate social networks therein. Results Pro-anorexia and pro-recovery communities interact to a much higher degree among themselves than what is expected from the distribution of contacts (only 59-72% of contacts but 74-83% of comments are made to members inside the community). Pro-recovery users employ similar words to those used by pro-anorexia users to describe their photographs, possibly in order to ensure that their content appears when pro-anorexia users search for images. Pro-anorexia users who are exposed to comments from the opposite camp are less likely to cease posting pro-anorexia photographs than those who do not receive such comments (46% versus 61%), and if they cease, they do so approximately three months later. Our observations show two highly active communities, where most interaction is within each community. However, the pro-recovery community takes steps to ensure that their content is visible to the pro-anorexia community, both by using textual descriptions of their photographs that are similar to those used by the pro-anorexia group and by commenting to pro-anorexia content. The latter activity is, however, counterproductive, as it entrenches pro-anorexia users in their stance. Conclusions Our results highlight the nature of pro-anorexia and pro

  12. When private actors matter: Information-sharing network and surveillance of Highly Pathogenic Avian Influenza in Vietnam.

    PubMed

    Delabouglise, A; Dao, T H; Truong, D B; Nguyen, T T; Nguyen, N T X; Duboz, R; Fournié, G; Antoine-Moussiaux, N; Grosbois, V; Vu, D T; Le, T H; Nguyen, V K; Salem, G; Peyre, M

    2015-07-01

    The effectiveness of animal health surveillance systems depends on their capacity to gather sanitary information from the animal production sector. In order to assess this capacity we analyzed the flow of sanitary information regarding Highly Pathogenic Avian Influenza (HPAI) suspicions in poultry in Vietnam. Participatory methods were applied to assess the type of actors and likelihood of information sharing between actors in case of HPAI suspicion in poultry. While the reporting of HPAI suspicions is mandatory, private actors had more access to information than public actors. Actors of the upstream sector (medicine and feed sellers) played a key role in the diffusion of information. The central role of these actors and the influence of the information flow on the adoption by poultry production stakeholders of behaviors limiting (e.g. prevention measures) or promoting disease transmission (e.g. increased animal movements) should be accounted for in the design of surveillance and control programs. PMID:25847263

  13. Application of the Actor-Critic Architecture to Functional Electrical Stimulation Control of a Human Arm.

    PubMed

    Thomas, Philip; Branicky, Michael; van den Bogert, Antonie; Jagodnik, Kathleen

    2009-01-01

    Clinical tests have shown that the dynamics of a human arm, controlled using Functional Electrical Stimulation (FES), can vary significantly between and during trials. In this paper, we study the application of the actor-critic architecture, with neural networks for the both the actor and the critic, as a controller that can adapt to these changing dynamics of a human arm. Development and tests were done in simulation using a planar arm model and Hill-based muscle dynamics. We begin by training it using a Proportional Derivative (PD) controller as a supervisor. We then make clinically relevant changes to the dynamics of the arm and test the actor-critic's ability to adapt without supervision in a reasonable number of episodes. Finally, we devise methods for achieving both rapid learning and long-term stability. PMID:20689654

  14. Pro-choice: a new militancy.

    PubMed

    Davis, S E

    1989-01-01

    Davis, a pro-choice advocate, describes the reactions of the abortion rights movement to the U.S. Supreme Court's opinion in the 1989 Webster v. Reproductive Health Services case. Viewing the decision that allows individual states to set some restrictions on abortion as a threat to women's reproductive rights, pro-choice advocates have responded "with a new sense of defiance and commitment." Davis describes the demonstrations, sit-ins, and coalitions that give evidence of the new activism of the pro-choice movement. PMID:2606658

  15. Manduca sexta proprophenoloxidase activating proteinase-3 (PAP3) stimulates melanization by activating proPAP3, proSPHs, and proPOs

    PubMed Central

    Wang, Yang; Lu, Zhiqiang; Jiang, Haobo

    2014-01-01

    Melanization participates in various insect physiological processes including antimicrobial immune responses. Phenoloxidase (PO), a critical component of the enzyme system catalyzing melanin formation, is produced as an inactive precursor prophenoloxidase (proPO) and becomes active via specific proteolytic cleavage by proPO activating proteinase (PAP). In Manduca sexta, three PAPs can activate proPOs in the presence of two serine proteinase homologs (SPH1 and SPH2). While the hemolymph proteinases (HPs) that generate the active PAPs are known, it is unclear how the proSPHs (especially proSPH1) are activated. In this study, we isolated from plasma of bar-stage M. sexta larvae an Ile-Glu-Ala-Arg-p-nitroanilide hydrolyzing enzyme that cleaved the proSPHs. This proteinase, PAP3, generated active SPH1 and SPH2, which function as cofactors for PAP3 in proPO activation. Cleavage of the purified recombinant proSPHs by PAP3 yielded 38 kDa bands similar in mobility to the SPHs formed in vivo. Surprisingly, PAP3 also can activate proPAP3 to stimulate melanization in a direct positive feedback loop. The enhanced proPO activation concurred with the cleavage activation of proHP6, proHP8, proPAP1, proPAP3, proSPH1, proSPH2, proPOs, but not proHP14 or proHP21. These results indicate that PAP3, like PAP1, is a key factor of the self-reinforcing mechanism in the proPO activation system, which is linked to other immune responses in M. sexta. PMID:24768974

  16. Power and pro-poor policies: the case of iCCM in Niger.

    PubMed

    Dalglish, Sarah L; Surkan, Pamela J; Diarra, Aïssa; Harouna, Abdoutan; Bennett, Sara

    2015-12-01

    Analyses of health policy in low- and middle-income countries frequently mention but rarely adequately explore power dynamics, whether or not the policy in question targets the poor. We present a case study in Niger of integrated community case management (iCCM), a policy to provide basic care for poor rural children sick with malaria, diarrhoea and pneumonia, which has contributed to measurable reductions in child mortality. We focus on the three dimensions of power in policymaking: political authority, financial resources and technical expertise. Data collection took place March to August 2012 and included semi-structured interviews with policy actors (N = 32), a document review (N = 103) and contextual analysis. Preliminary data analysis relied on process tracing methodology to examine why iCCM was prioritized and identify dimensions of power most relevant to the Nigerien case; we then applied theoretical categories deductively to our data. We find that political authorities, namely President Mamadou Tandja, created the underlying health infrastructure for the policy ('health huts') as a way to distribute rents from development aid through client networks while claiming the mantle of political legitimacy. Conditional influxes of financial resources created an incentive to declare fee exemptions for children below 5 years, a key condition for the policy's success. Technical expertise was concentrated among international actors from multi-lateral and bilateral agencies who packaged and delivered scientific arguments in support of iCCM to Nigerien policymakers, whose input was limited mainly to operational decisions. The Nigerien case sheds light on the dimensions of power in health policymaking, particularly in neo-patrimonial African regimes, and provides insights on how external actors can work within these contexts to promote pro-poor policies. PMID:26516154

  17. Technology evaluation: PRO-542, Progenics Pharmaceuticals inc.

    PubMed

    Mukhtar, M; Parveen, Z; Pomerantz, R J

    2000-12-01

    Progenics's rCD4-IgG2 (PRO-542) is a recombinant fusion protein, which has been developed using the company's Universal Antiviral Binding (UnAB) technology, and is in phase I/II clinical trials for the treatment of human immunodeficiency virus type I (HIV-1) infection [273391]. At the beginning of 1997, Progenics received a Phase II Small Business Innovation Research Program (SBIR) grant from the National Institute of Allergy and Infectious diseases (NIAID) to fund the development of PRO-542 [236048]. A further grant of $2.7 million was awarded in August 1998 for the clinical evaluation of PRO-542 and other anti-HIV therapies [294200]. Progenics is collaborating with the Aaron Diamond AIDS Research Center (ADARC) in New York and the Center for Disease Control and Prevention in Atlanta [178410]. In February 2000, Progenics and Genzyme Transgenics Corp signed an agreement to continue the development of a transgenic source of PRO-542. Genzyme will develop transgenic goats that produce PRO-542 in their milk in exchange for undisclosed fees and milestone payments. Genzyme will supply PRO-542 to Progenics for clinical trials with a possibility for eventual commercial supply [357291]. Following on from this, in October 2000, Progenics received an SBIR grant to fund a two-year project with Genzyme Transgenics into the development of cost-effective methods for the manufacture of PRO-542, by optimization of the production of the drug in the milk of transgenic dairy animals [385982]. In August 2000, Punk, Ziegel & Company predicted that Progenics Pharmaceuticals will become sustainably profitable in 2003 following the launch of PRO-542 and GMK (Progenics Pharmaceuticals) in 2002 [390063]. PMID:11249748

  18. Temporal Effects of Performance on Causal Attributions in Actors and Observers.

    ERIC Educational Resources Information Center

    Bryant, Fred B.

    Although understanding how causal attributions for performance develop is important to attribution theory, little research has been done on this topic. To explore changes in attributions during task performance for both actors and observers, 90 female undergraduates participated in a procedure in which they received either 80 percent or 20 percent…

  19. Toddlers as Both More and Less Competent Social Actors in Finnish Day Care Centres

    ERIC Educational Resources Information Center

    Kalliala, Marjatta

    2014-01-01

    In recent decades, the notion of the competent child has, in the field of Early Childhood Education, become a powerful discourse. In this paradigm, inspired by the sociology of childhood, the child is seen as a competent social actor having agency in his or her life. However, critical comments have been made at both the micro-and macro-level about…

  20. Inside the Actors' Studio: Exploring Dietetics Education Practices through Dialogical Inquiry

    ERIC Educational Resources Information Center

    Fox, Ann L.; Gingras, Jacqui

    2012-01-01

    Two colleagues, Ann and Jacqui, came together, within the safety of an imagined actors' studio, to explore the challenges that Ann faced in planning a new graduate program in public health nutrition. They met before, during, and after program implementation to discuss Ann's experiences, and audio-taped and transcribed the discussions. When all…

  1. Exchange Studies as Actor-Networks: Following Korean Exchange Students in Swedish Higher Education

    ERIC Educational Resources Information Center

    Ahn, Song-ee

    2011-01-01

    This article explores how Korean exchange students organized their studies during exchange programs in Swedish higher education. For most students, the programs became a disordered period in relation to their education. The value of exchange studies seems mainly to be extra-curricular. Drawing upon actor network theory, the article argues that the…

  2. ("un")Doing the Next Generation Science Standards: Climate Change Education Actor-Networks in Oklahoma

    ERIC Educational Resources Information Center

    Colston, Nicole M.; Ivey, Toni A.

    2015-01-01

    This exploratory research investigated how science education communities of practice in Oklahoma engage in translations of climate change education (CCE). Applications of actor-network theory to educational policymaking facilitate this analysis of the spaces of prescription and spaces of negotiation that characterize CCE in Oklahoma. Informed by…

  3. ("Un")Doing Standards in Education with Actor-Network Theory

    ERIC Educational Resources Information Center

    Fenwick, Tara J.

    2010-01-01

    Recent critiques have drawn important attention to the depoliticized consensus and empty promises embedded in network discourses of educational policy. While acceding this critique, this discussion argues that some forms of network analysis--specifically those adopting actor-network theory (ANT) approaches--actually offer useful theoretical…

  4. Recent Trends in Intergovernmental Relations: The Resurgence of Local Actors in Education Policy

    ERIC Educational Resources Information Center

    Marsh, Julie A.; Wohlstetter, Priscilla

    2013-01-01

    In this essay, the authors explore trends in intergovernmental relations (IGR) by analyzing recent education policies--No Child Left Behind Act, Common Core State Standards, and local empowerment policies. Identifying a resurgent role for local actors in education policy, the authors argue that recent federal efforts to exert more control have in…

  5. Early Social Fear in Relation to Play with an Unfamiliar Peer: Actor and Partner Effects

    ERIC Educational Resources Information Center

    Walker, Olga L.; Degnan, Kathryn A.; Fox, Nathan A.; Henderson, Heather A.

    2015-01-01

    The purpose of this study was to examine the associations between maternal reports of social fear at 24 months and social behaviors with an unfamiliar peer during play at 36 months, using the Actor-Partner Interdependence Model (APIM; Kashy & Kenny, 1999). The APIM model was used to not only replicate previous findings of direct effects of…

  6. The Role of Key Actors in School Governance: An Italian Evidence

    ERIC Educational Resources Information Center

    Salvioni, Daniela; Gandini, Giuseppina; Franzoni, Simona; Gennari, Francesca

    2012-01-01

    The greater awareness of the role of key actors in the school governance processes and the need to expect a "new leader" in the increasing school complexity are essential conditions to reform the schools from within, so as to provide them with skills related to globalisation, improvement to the educational quality, strengthening of positive…

  7. Modeling Homophily over Time with an Actor-Partner Interdependence Model

    ERIC Educational Resources Information Center

    Popp, Danielle; Laursen, Brett; Kerr, Margaret; Stattin, Hakan; Burk, William J.

    2008-01-01

    Selection and socialization have been implicated in friendship homophily, but the relative contributions of each are difficult to measure simultaneously because of the nonindependent nature of the data. To address this problem, the authors applied a multiple-groups longitudinal actor-partner interdependence model (D. A. Kashy & D. A. Kenny, 2000)…

  8. Assessing Mediation in Dyadic Data Using the Actor-Partner Interdependence Model

    ERIC Educational Resources Information Center

    Ledermann, Thomas; Macho, Siegfried; Kenny, David A.

    2011-01-01

    The assessment of mediation in dyadic data is an important issue if researchers are to test process models. Using an extended version of the actor-partner interdependence model the estimation and testing of mediation is complex, especially when dyad members are distinguishable (e.g., heterosexual couples). We show how the complexity of the model…

  9. Scientific Journals of Universities of Chile, Colombia, and Venezuela: Actors and Roles

    ERIC Educational Resources Information Center

    Delgado, Jorge Enrique

    2014-01-01

    A qualitative study was carried out to identify the roles of actors associated with the publication of scientific journals in Chilean, Colombian, and Venezuelan universities. Twenty-four semi-structured in-depth interviews were conducted with journal editors, university authorities, and other experts. The categories of analysis included university…

  10. Whose Quality? Social Actors in the Interface of Transnational and National Higher Education Policy

    ERIC Educational Resources Information Center

    Saarinen, Taina

    2008-01-01

    The article analyzes the construction of national reactions to a transnational higher education policy from the point of view of the representation of social actors in policy documents. The data are provided by the so-called Bologna Process, particularly the development of comparable quality assurance systems, and Finnish responses to those…

  11. Learning Science in a Virtual Reality Application: The Impacts of Animated-Virtual Actors' Visual Complexity

    ERIC Educational Resources Information Center

    Kartiko, Iwan; Kavakli, Manolya; Cheng, Ken

    2010-01-01

    As the technology in computer graphics advances, Animated-Virtual Actors (AVAs) in Virtual Reality (VR) applications become increasingly rich and complex. Cognitive Theory of Multimedia Learning (CTML) suggests that complex visual materials could hinder novice learners from attending to the lesson properly. On the other hand, previous studies have…

  12. Reading Theatre, Parents as Actors: Movie Production in a Family Literacy Workshop

    ERIC Educational Resources Information Center

    Huang, Grace; Dolejs, Barbara

    2007-01-01

    The goal of the family literacy workshop "Reading Theatre, Parents as Actors: Movie production in a Family Literacy Workshop" is to empower and motivate parents to learn various storytelling strategies through theatrical production experiences and apply them at home. This is a theory-based family literacy practice supported by McClelland's…

  13. Learning through Civic Participation: Policy Actors' Perspectives on Curriculum Reform Involvement in Ontario

    ERIC Educational Resources Information Center

    Pinto, Laura Elizabeth

    2014-01-01

    When citizens participate in policy production, the advantages go beyond policy outcomes--though the presumption is that participation leads to better public policy. Robust democracy characterized by agonistic exchanges among policy actors ought to encourage learning, dialogue, empow­erment, equity, and a shared spirit of inquiry. This article…

  14. Attachment Anxiety and Avoidance and Perceptions of Group Climate: An Actor-Partner Interdependence Analysis

    ERIC Educational Resources Information Center

    Kivlighan, Dennis M.; Lo Coco, Gianluca; Gullo, Salvatore

    2012-01-01

    There is a lack of research examining group members' attachment styles and group climate perceptions in the context of the attachment styles and group climate perceptions of the other group members. In the current study, the actor-partner interdependence model (APIM) was used to examine the relationships among (a) a group member's attachment…

  15. Coordination between Governance Actors in Universities: The Role of Policy Documents

    ERIC Educational Resources Information Center

    Macheridis, Nikos

    2015-01-01

    This article focuses on coordination between governance actors in a public university. The purpose of this paper is to illustrate and analyze policy documents as governance tools that allow departmental management to coordinate with the authorities, the board, and the management at different university levels. A central finding is that the…

  16. Developing Integrated Rural Tourism: Actor Practices in the English/Welsh Border

    ERIC Educational Resources Information Center

    Saxena, Gunjan; Ilbery, Brian

    2010-01-01

    This paper examines community attitudes and distinctive practices that shape local responses to integrated rural tourism (IRT) development in the lagging rural region of the English/Welsh border area. The focus is on how actors acquire attributes as a result of their relations with others and how these assumed identities are performed in, by and…

  17. Learning to Act/Acting to Learn: Children as Actors, Critics, and Characters in Classroom Theatre.

    ERIC Educational Resources Information Center

    Wolf, Shelby Anne

    1994-01-01

    Investigates the experiences of 17 "remedial" readers as they interpreted and performed texts through classroom theater. Discusses results of a study aimed at analyzing patterns of children's text interpretation. Details the students' evolving conception of themselves as actors and interpreters of texts. (HB)

  18. Tolerance of Practices by Muslim Actors: An Integrative Social-Developmental Perspective

    ERIC Educational Resources Information Center

    Gieling, Maike; Thijs, Jochem; Verkuyten, Maykel

    2010-01-01

    Using social-cognitive domain theory and social identity theory, tolerance judgments of practices by Muslim actors among Dutch adolescents (12-17) were investigated. The findings for Study 1 (N = 180) demonstrated that participants evaluated 4 practices using different types of reasons: personal, social-conventional, and moral. In Study 2 (N =…

  19. Beyond Dyadic Interdependence: Actor-Oriented Models for Co-Evolving Social Networks and Individual Behaviors

    ERIC Educational Resources Information Center

    Burk, William J.; Steglich, Christian E. G.; Snijders, Tom A. B.

    2007-01-01

    Actor-oriented models are described as a longitudinal strategy for examining the co-evolution of social networks and individual behaviors. We argue that these models provide advantages over conventional approaches due to their ability to account for inherent dependencies between individuals embedded in a social network (i.e., reciprocity,…

  20. Seven Consciousness-Expanding Techniques and Their Relevance to Actor Training.

    ERIC Educational Resources Information Center

    Feldshuh, David Mark

    This dissertation explores techniques that assist actors in getting their minds and bodies out of the way through consciousness-expanding. The techniques examined here attempt to promote a permeability, a childlike quality of presence, and are largely drawn from Eastern philosophies. Part one of this dissertation discusses structural integration,…

  1. Extended mind and after: socially extended mind and actor-network.

    PubMed

    Kono, Tetsuya

    2014-03-01

    The concept of extended mind has been impressively developed over the last 10 years by many philosophers and cognitive scientists. The extended mind thesis (EM) affirms that the mind is not simply ensconced inside the head, but extends to the whole system of brain-body-environment. Recently, some philosophers and psychologists try to adapt the idea of EM to the domain of social cognition research. Mind is socially extended (SEM). However, EM/SEM theory has problems to analyze the interactions among a subject and its surroundings with opposition, antagonism, or conflict; it also tends to think that the environment surrounding the subject is passive or static, and to neglect the power of non-human actants to direct and regulate the human subject. In these points, actor-network theory (ANT) proposed by Latour and Callon is more persuasive, while sharing some important ideas with EM/SEM theory. Actor-network is a hybrid community which is composed of a series of heterogeneous elements, animate and inanimate for a certain period of time. I shall conclude that EM/SEM could be best analyzed as a special case of actor-network. EM/SEM is a system which can be controlled by a human agent alone. In order to understand collective behavior, philosophy and psychology have to study the actor-network in which human individuals are situated. PMID:23975479

  2. Students' Inventory of Social Actors Concerned by the Controversy Surrounding Cellular Telephones: A Case Study

    ERIC Educational Resources Information Center

    Pouliot, Chantal

    2008-01-01

    The present article scrutinizes the manner with which a group of three postsecondary students (in Quebec, Canada) describe the social actors concerned by the controversy surrounding cellular telephones. The study was conducted on the basis of an ethnographic approach. Participant observation was performed by the researcher for 3 hours during each…

  3. Managing the Dynamics of the Bologna Reforms: How Institutional Actors Re-Construct the Policy Framework

    ERIC Educational Resources Information Center

    Veiga, Amélia; Neave, Guy

    2015-01-01

    How do the constituencies in higher education re-interpret Bologna's function with regard to the European Higher Education Area? This research examines how institutional actors re-construct the policy framework in the light of their own institutional agendas. Drawing on empirical data from a survey of academics, students and administrative and…

  4. What the Words Mean: Teaching Young Actors the Value of Language.

    ERIC Educational Resources Information Center

    Miller, Bruce

    1999-01-01

    Confronts the challenges of getting young actors to embrace the use of language. Presents a series of exercises designed to expose students to the potential power of the spoken word by using three different kinds of texts: advertising copy, children's storybooks, and the Pledge of Allegiance to the flag. Discusses how the author engages his…

  5. Ordering Subjects: Actor-Networks and Intellectual Technologies in Lifelong Learning.

    ERIC Educational Resources Information Center

    Edwards, Richard

    2003-01-01

    Argues that discourses of lifelong learning act as intellectual technologies that construct individuals as subjects in a learning society. Discuses three discourses using actor-network theory: (1) economics/human capital (individuals as accumulators of skills for competitiveness); (2) humanistic psychology (individuals seeking fulfilment through…

  6. Invisible Actors: The Oromo and the Creation of Modern Ethiopia (1855-1913)

    ERIC Educational Resources Information Center

    Yates, Brian James

    2009-01-01

    This is a comprehensive study of key Oromo actors in the central Ethiopia traditional provinces of Wallo and Shawa, specifically the Mammadoch of Wallo and the Tulama of Shawa during the reigns of Emperors Tewodros II (r.1855-68), Yohannes IV (1872-1888) and Menilek II (1889-1913). The Oromo entered the political arena in the highlands of Ethiopia…

  7. Effects Of Principal Actor Time Structuring On Goal Attainment In Group Counseling

    ERIC Educational Resources Information Center

    Jessell, John C.; Bush, John F.

    1973-01-01

    Subjects were 84 university and high school students. Data was obtained from responses to a behavioral goal questionnaire and the Truax Relationship Inventory. Structuring of group counseling through the use of principal actor time did not result in differential goal attainment between clients of structured or unstructured groups. Neither was any…

  8. Movement Actors in the Education Bureaucracy: The Figured World of Activity Based Learning in Tamil Nadu

    ERIC Educational Resources Information Center

    Niesz, Tricia; Krishnamurthy, Ramchandar

    2014-01-01

    Tamil Nadu has gained international recognition for reforming its government school classrooms into active, child-centered learning environments. Our exploration of the history of the Activity Based Learning movement suggests that this reform was achieved by social movement actors serving in and through the state's administration.…

  9. Social health insurance without corporate actors: changes in self-regulation in Germany, Poland and Turkey.

    PubMed

    Wendt, Claus; Agartan, Tuba I; Kaminska, Monika Ewa

    2013-06-01

    Social health insurance in Western Europe has for many years been characterized by self-regulation in which specific conditions of healthcare financing and provision have been regulated by social-insurance institutions through mutual self-governance. However, the principle of self-regulation has recently been weakened by increased state regulation and market competition, which were introduced in response to economic and social changes. Even in Germany, which has been regarded as an "ideal-type" health insurance system and in which self-regulation remains at the core of healthcare governance, more direct state intervention has gained in importance. On the other hand, in countries such as Poland and Turkey, where this tradition of self-regulation is missing, social health insurance is deemed a financing instrument but not an instrument of governance and corporate actors are not accorded a significant role in regulation. This article investigates how social health insurance systems are regulated in contexts in which corporate actors' role is either diminishing or absent by focusing on three crucial areas of regulation: financing, the remuneration of medical doctors, and the definition of the healthcare benefit package. In Germany, state regulation has increased in healthcare financing and remuneration while the role of corporate actors has grown in the definition of the benefits package. In Poland and Turkey, on the other hand, reforms have maintained the status quo in terms of the strong regulatory, budgetary, and managerial powers of the state and very limited involvement of corporate actors. PMID:23608097

  10. New Plays from A.C.T.'s Young Conservatory. Volume II. Young Actors Series.

    ERIC Educational Resources Information Center

    Slaight, Craig, Ed.

    This collection of new plays for young actors comes from the repertoire of the Young Conservatory, a professional theater training program for young people ages 8 to 18 at the American Conservatory Theater. Each of the five plays in the collection was developed in this way: an outstanding professional playwright is invited to create a new play…

  11. Actor Vocal Training for the Habilitation of Speech in Adolescent Users of Cochlear Implants

    ERIC Educational Resources Information Center

    Holt, Colleen M.; Dowell, Richard C.

    2011-01-01

    This study examined changes to speech production in adolescents with hearing impairment following a period of actor vocal training. In addition to vocal parameters, the study also investigated changes to psychosocial factors such as confidence, self-esteem, and anxiety. The group were adolescent users of cochlear implants (mean age at commencement…

  12. Why Do Policy Frames Change? Actor-Idea Coevolution in Debates over Welfare Reform

    ERIC Educational Resources Information Center

    Steensland, Brian

    2008-01-01

    One shortcoming in the literature on policy framing has been the absence of analytic models through which to explicate change. This paper advances research in this area in three related ways. First, it links policy frames to the actors who employ them. Second, based upon this linkage it proposes two complementary approaches for examining…

  13. Protein ProQ Influences Osmotic Activation of Compatible Solute Transporter ProP in Escherichia coli K-12

    PubMed Central

    Kunte, H. Jörg; Crane, Rebecca A.; Culham, Doreen E.; Richmond, Deborah; Wood, Janet M.

    1999-01-01

    ProP is an osmoregulatory compatible solute transporter in Escherichia coli K-12. Mutation proQ220::Tn5 decreased the rate constant for and the extent of ProP activation by an osmotic upshift but did not alter proP transcription or the ProP protein level. Allele proQ220::Tn5 was isolated, and the proQ sequence was determined. Locus proQ is upstream from prc (tsp) at 41.2 centisomes on the genetic map. The proQ220::Tn5 and prc phenotypes were different, however. Gene proQ is predicted to encode a 232-amino-acid, basic, hydrophilic protein (molecular mass, 25,876 Da; calculated isoelectric point, 9.66; 32% D, E, R, or K; 54.5% polar amino acids). The insertion of PCR-amplified proQ into vector pBAD24 produced a plasmid containing the wild-type proQ open reading frame, the expression of which yielded a soluble protein with an apparent molecular mass of 30 kDa. Antibodies raised against the overexpressed ProQ protein detected cross-reactive material in proQ+ bacteria but not in proQ220::Tn5 bacteria. ProQ may be a structural element that influences the osmotic activation of ProP at a posttranslational level. PMID:10049386

  14. Actor-critic models of the basal ganglia: new anatomical and computational perspectives.

    PubMed

    Joel, Daphna; Niv, Yael; Ruppin, Eytan

    2002-01-01

    A large number of computational models of information processing in the basal ganglia have been developed in recent years. Prominent in these are actor-critic models of basal ganglia functioning, which build on the strong resemblance between dopamine neuron activity and the temporal difference prediction error signal in the critic, and between dopamine-dependent long-term synaptic plasticity in the striatum and learning guided by a prediction error signal in the actor. We selectively review several actor-critic models of the basal ganglia with an emphasis on two important aspects: the way in which models of the critic reproduce the temporal dynamics of dopamine firing, and the extent to which models of the actor take into account known basal ganglia anatomy and physiology. To complement the efforts to relate basal ganglia mechanisms to reinforcement learning (RL), we introduce an alternative approach to modeling a critic network, which uses Evolutionary Computation techniques to 'evolve' an optimal RL mechanism, and relate the evolved mechanism to the basic model of the critic. We conclude our discussion of models of the critic by a critical discussion of the anatomical plausibility of implementations of a critic in basal ganglia circuitry, and conclude that such implementations build on assumptions that are inconsistent with the known anatomy of the basal ganglia. We return to the actor component of the actor-critic model, which is usually modeled at the striatal level with very little detail. We describe an alternative model of the basal ganglia which takes into account several important, and previously neglected, anatomical and physiological characteristics of basal ganglia-thalamocortical connectivity and suggests that the basal ganglia performs reinforcement-biased dimensionality reduction of cortical inputs. We further suggest that since such selective encoding may bias the representation at the level of the frontal cortex towards the selection of rewarded

  15. Actor-specific contributions to the deforestation slowdown in the Brazilian Amazon.

    PubMed

    Godar, Javier; Gardner, Toby A; Tizado, E Jorge; Pacheco, Pablo

    2014-10-28

    Annual deforestation rates in the Brazilian Amazon fell by 77% between 2004 and 2011, yet have stabilized since 2009 at 5,000-7,000 km(2). We provide the first submunicipality assessment, to our knowledge, of actor-specific contributions to the deforestation slowdown by linking agricultural census and remote-sensing data on deforestation and forest degradation. Almost half (36,158 km(2)) of the deforestation between 2004 and 2011 occurred in areas dominated by larger properties (>500 ha), whereas only 12% (9,720 km(2)) occurred in areas dominated by smallholder properties (<100 ha). In addition, forests in areas dominated by smallholders tend to be less fragmented and less degraded. However, although annual deforestation rates fell during this period by 68-85% for all actors, the contribution of the largest landholders (>2,500 ha) to annual deforestation decreased over time (63% decrease between 2005 and 2011), whereas that of smallholders went up by a similar amount (69%) during the same period. In addition, the deforestation share attributable to remote areas increased by 88% between 2009 and 2011. These observations are consistent across the Brazilian Amazon, regardless of geographical differences in actor dominance or socioenvironmental context. Our findings suggest that deforestation policies to date, which have been particularly focused on command and control measures on larger properties in deforestation hotspots, may be increasingly limited in their effectiveness and fail to address all actors equally. Further reductions in deforestation are likely to be increasingly costly and require actor-tailored approaches, including better monitoring to detect small-scale deforestation and a shift toward more incentive-based conservation policies. PMID:25313087

  16. E-health approach to link-up actors in the health care system of Austria.

    PubMed

    Schabetsberger, Thomas; Ammenwerth, Elske; Breu, Ruth; Hoerbst, Alexander; Goebel, Georg; Penz, Robert; Schindelwig, Klaus; Toth, Herlinde; Vogl, Raimund; Wozak, Florian

    2006-01-01

    "Electronic health services are important" the EU commission stated in the E-Health action plan. By these means access to health care can be improved and the quality and effect of the offered medical services can be increased. By introducing the e-card in Austria, an overall link-up of nearly all health service providers of the external sector (e.g. family doctors) was achieved. In 2005 the Austrian E-Health Initiative (EHI) of the Austrian Federal Ministry for Health and Women mapped out a strategy to organise the development of the health system towards an integrated patient-centred. Hereby the electronic health record (EHR) plays a decisive role. The aim of this study is to analyse requirements for a virtual, cross-institutional and patient-centred electronic health record from the point of view of the exemplary main actors (Doctor and Patient), to define conditions, and then to evaluate the thus derived, specific concept of implementation. Aside from the two main actors regarding medical acts, namely the institution treating a patient (e.g. doctor, paramedic or nurse) and the patient receiving treatment, a row of other actors could be identified. Group assessment techniques with representatives of these actors resulted in an overview of required functions of an EHR. As a proof-of-concept an information system architecture conformable to the IHE XDS architecture for cross enterprise document sharing is currently being constructed and evaluated in the course of a pilot-project. If the core architecture fulfils the expectations, then a further extension to other hospitals and resident doctors, and subsequently also to the other actors of the health system, is planned. Since both legal and socio-technical requirements are presently not yet entirely met, and since there are also deficits from a methodical viewpoint, a complete implementation and widespread introduction will be a long term goal. PMID:17108555

  17. 31 CFR 50.92 - Determination of pro rata share.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Determination of pro rata share. 50... INSURANCE PROGRAM Cap on Annual Liability § 50.92 Determination of pro rata share. (a) Pro rata loss... compliance with pro rata payments in accordance with the effective date of the PRLP. (2) Determine an...

  18. Marital Relationship Quality and Couples' Cognitive Stimulation Practices toward Their Infants: Actor and Partner Effects of White and Hispanic Parents

    ERIC Educational Resources Information Center

    Sotomayor-Peterson, Marcela; Wilhelm, Mari S.; Card, Noel A.

    2011-01-01

    The present study explores actor and partner effects on mothers' and fathers' cognitive stimulation within an Actor-Partner Interdependence Model (APIM). This model allows us to evaluate whether mothers' and fathers' practices are impacted not only by their own experiences but also by their partners' experiences. The APIM treats the couple as the…

  19. From Capitol Hill to Dupont Circle and Beyond: The Influence of Policy Actors in the Federal Higher Education Rulemaking Process

    ERIC Educational Resources Information Center

    Natow, Rebecca S.

    2015-01-01

    The federal higher education rulemaking process develops policies that can profoundly affect college students, higher education institutions, and other actors in the higher education policy community. But little has been researched about the influence that different types of actors have on higher education rulemaking. By analyzing interviews with…

  20. Teachers as Language-Policy Actors: Contending with the Erasure of Lesser-Used Languages in Schools

    ERIC Educational Resources Information Center

    Brown, Kara

    2010-01-01

    On the basis of an ethnographic study of the Voro-language revitalization in Estonia, this article explores the way teachers function as policy actors in the broader context of the school. As policy actors, the language teachers' appropriation of regional-language policy helps simultaneously to reproduce and challenge existing ideologies in the…

  1. Side Effects: An Analysis of Mind the Gap's "Boo" and the Reception of Theatre Involving Learning Disabled Actors

    ERIC Educational Resources Information Center

    Hargrave, Matt

    2010-01-01

    This article analyses Mind the Gap's Boo, a re-imagining of Harper Lee's "To Kill a Mockingbird", which features a cast of learning disabled actors. It is concerned with the public reception of the work, particularly the "effect" of an all-disabled cast. What are the consequences, both ethical and aesthetic, for these actors to tell this story on…

  2. Action observers implicitly expect actors to act goal-coherently, even if they do not: an fMRI study.

    PubMed

    Hrkać, Mari; Wurm, Moritz F; Schubotz, Ricarda I

    2014-05-01

    Actions observed in everyday life normally consist of one person performing sequences of goal-directed actions. The present fMRI study tested the hypotheses that observers are influenced by the actor's identity, even when this information is task-irrelevant, and that this information shapes their expectation on subsequent actions of the same actor. Participants watched short video clips of action steps that either pertained to a common action with an overarching goal or not, and were performed by either one or by varying actors (2 × 2 design). Independent of goal coherence, actor coherence elicited activation in dorsolateral and ventromedial frontal cortex, together pointing to a spontaneous attempt to integrate all actions performed by one actor. Interestingly, watching an actor performing unrelated actions elicited additional activation in left inferior frontal gyrus, suggesting a search in semantic memory in an attempt to construct an overarching goal that can reconcile the disparate action steps with a coherent intention. Post-experimental surveys indicate that these processes occur mostly unconsciously. Findings strongly suggest a spontaneous expectation bias toward actor-related episodes in action observers, and hence to the immense impact of actor information on action observation. PMID:23983202

  3. Human melioidosis reported by ProMED

    PubMed Central

    Nasner-Posso, Katherinn Melissa; Cruz-Calderón, Stefania; Montúfar-Andrade, Franco E.; Dance, David A.B.; Rodriguez-Morales, Alfonso J.

    2015-01-01

    Summary Objective There are limited sources describing the global burden of emerging diseases. A review of human melioidosis reported by ProMED was performed and the reliability of the data retrieved assessed in comparison to published reports. The effectiveness of ProMED was evaluated as a source of epidemiological data by focusing on melioidosis. Methods Using the keyword ‘melioidosis’ in the ProMED search engine, all of the information from the reports and collected data was reviewed using a structured form, including the year, country, gender, occupation, number of infected individuals, and number of fatal cases. Results One hundred and twenty-four entries reported between January 1995 and October 2014 were identified. A total of 4630 cases were reported, with death reported in 505 cases, suggesting a misleadingly low overall case fatality rate (CFR) of 11%. Of 20 cases for which the gender was reported, 12 (60%) were male. Most of the cases were reported from Australia, Thailand, Singapore, Vietnam, and Malaysia, with sporadic reports from other countries. Conclusions Internet-based reporting systems such as ProMED are useful to gather information and synthesize knowledge on emerging infections. Although certain areas need to be improved, ProMED provided good information about melioidosis. PMID:25975651

  4. Vocal projection in actors: the long-term average spectral features that distinguish comfortable acting voice from voicing with maximal projection in male actors.

    PubMed

    Pinczower, Rachel; Oates, Jennifer

    2005-09-01

    This study explored whether acoustic and perceptual features could distinguish comfortable from maximally projected acting voice. Thirteen professional male actors performed a passage from William Shakespeare's Julius Caesar twice. The first delivery used their comfortably projected voices, whereas the second used maximal projection. Acoustic measures, expert ratings, and self-ratings of projection and voice quality were investigated. Long-term average spectra (LTAS) and sound pressure level (SPL) analyses were conducted. Perceptual variables included projection, breathiness, roughness, and strain. When comparing the intensity difference between the higher (2-4 kHz) and lower (0-2 kHz) regions of the spectrum in voice samples from the maximal projected condition, LTAS analyses demonstrated increased acoustic energy in the higher part of the spectrum. This LTAS pattern was not as evident in the comfortable projected condition. These findings offered some preliminary support for the existence of an actor's formant (prominent peak in the upper part of the spectrum) during maximal projection. PMID:16102670

  5. A climate game based on a Multi-Actor Dynamic Integrated Assessment Model (MADIAM)

    NASA Astrophysics Data System (ADS)

    Weber, M.; Hasselmann, K.

    2003-04-01

    In November 2002 a special exhibition on climate issues opened in the German Museum for Science and Techniques ('Deutsches Museum') in Munich. Within this exposition we present an interactive game in which visitors control future climate policy by adopting the role of either the government, a CEO (Chief Executive Officer) of a global company or a typical private household of an industrialized country. The players endeavor to maintain a sustainable climate in the future (global goal) while pursuing their own individual welfare goals. Task of the exhibition visitor is to combine the personal interests of the actor he is adopting with the global goal. The individual goal of government is maintain economic growth while avoiding conflicts due to inter-regional or societal inequalities. The CEO seeks to maximize total profits (business earnings). The goal of households is to maximize wages and interest earnings. The evolution of the economic system and climate is governed by the decisions of the actors. Government sets economic side conditions in terms of carbon taxes, subsidies for R&D or market infusion support for climate-friendly technologies, and transfers development aid to less advanced regions. The CEOs decide how much to invest in a number of alternative investment options and in which region. Households influences the economy by their purchasing and savings decisions. The model considers four regions, three real actors (mentioned above) and two different goods (climate-adverse and a climate-friendly). We introduce four different kinds of energy (coal, oil/gas, nuclear, renewable). A World Bank handles money flows. At different points in time the actors can cooperate with other actors in order to reach the global goal Stochastic elements regarding future technology and future climate are included. A touch-screen monitor with user friendly interface is used to present animations and videos. An animated climate scientist uses a climate simulator to compute future

  6. A Poor Man's Nuclear Deterrent: Assessing the Value of Radiological Weapons for State Actors

    NASA Astrophysics Data System (ADS)

    Donohue, Nathan

    The threat of weapons of mass destruction is an issue which remains at the forefront on national security. Nuclear, chemical, and biological weapons are all considered very dangerous by both state and non-state actors. Radiological weapons exist in that same category yet are not held in the same regard; the reason that is given is that these types of weapons are not the weapons of mass destruction that the other three are. Instead, radiological weapons are better considered weapons of mass disruption. Accordingly, in the academic and policy literature there has been very little perceived value associated with such weapons for use by state actors. However the historical focus on the military efficacy of radiological weapons has obscured the obvious truth that they may pose significant value for state actors. What this research shows is that the explosion of a radiological weapon could disrupt a target area in ways which could cripple the economy of an adversary state and promote widespread fear concerning exposure to radiation. Any such attack would not only necessitate large scale evacuation, but cleanup, decontamination, demolition, territory exclusion, and relocation. Moreover, the effects of such an attack would be unlikely to remain an isolated event as evacuated and displaced citizens spread across the nation carrying both fear and residual radiation. All of these factors would only be compounded by a state actor's ability to not only develop such weapons, but to manufacture them in such a composition that contemporary examples of such weapons grossly underestimate their impact. Accordingly, radiological weapons could hold great value for any state actor wishing to pursue their development and to threaten their use. Moreover, "while RDDs may not be well suited as "military weapons" in the classic sense, the use of RDDs could be powerfully coercive."1 In that sense, state actors could even acquire radiological weapons for their deterrent value. 1James L. Ford

  7. Alternative manifestations of actor responses to urban flooding: case studies from Bradford and Glasgow.

    PubMed

    Cashman, A C

    2009-01-01

    Flooding processes are complex and can occur throughout urban areas sometimes with devastating consequences. Traditionally flood risks have been managed through a combination of structural defence measures, warnings and emergency measures. More recently they have included development controls and land zoning policies. When such measures fail, individuals, authorities and the economy have to cope with the consequences. There is a growing realization that the resilience of individuals and institutions to floods and the risks from flooding need to be addressed. In the past few years there has been what some have referred to as a paradigm shift in the way responses to flooding are being conceptualized and the way this affects actors and actions. Based on fieldwork including interviews this paper presents two examples of actor and institutional responses to flooding events from the cities of Bradford and Glasgow in the United Kingdom. PMID:19587405

  8. Actor-network theory: a tool to support ethical analysis of commercial genetic testing.

    PubMed

    Williams-Jones, Bryn; Graham, Janice E

    2003-12-01

    Social, ethical and policy analysis of the issues arising from gene patenting and commercial genetic testing is enhanced by the application of science and technology studies, and Actor-Network Theory (ANT) in particular. We suggest the potential for transferring ANT's flexible nature to an applied heuristic methodology for gathering empirical information and for analysing the complex networks involved in the development of genetic technologies. Three concepts are explored in this paper--actor-networks, translation, and drift--and applied to the case of Myriad Genetics and their commercial BRACAnalysis genetic susceptibility test for hereditary breast cancer. Treating this test as an active participant in socio-technical networks clarifies the extent to which it interacts with, shapes and is shaped by people, other technologies, and institutions. Such an understanding enables more sophisticated and nuanced technology assessment, academic analysis, as well as public debate about the social, ethical and policy implications of the commercialization of new genetic technologies. PMID:15115034

  9. Reinforcement learning for a biped robot based on a CPG-actor-critic method.

    PubMed

    Nakamura, Yutaka; Mori, Takeshi; Sato, Masa-aki; Ishii, Shin

    2007-08-01

    Animals' rhythmic movements, such as locomotion, are considered to be controlled by neural circuits called central pattern generators (CPGs), which generate oscillatory signals. Motivated by this biological mechanism, studies have been conducted on the rhythmic movements controlled by CPG. As an autonomous learning framework for a CPG controller, we propose in this article a reinforcement learning method we call the "CPG-actor-critic" method. This method introduces a new architecture to the actor, and its training is roughly based on a stochastic policy gradient algorithm presented recently. We apply this method to an automatic acquisition problem of control for a biped robot. Computer simulations show that training of the CPG can be successfully performed by our method, thus allowing the biped robot to not only walk stably but also adapt to environmental changes. PMID:17412559

  10. [The emergence and institutionalization of sexology in Portugal: processes, actors, and specificities].

    PubMed

    Alarcão, Violeta; Machado, Fernando Luís; Giami, Alain

    2016-01-01

    Based on Bourdieu's field theory, this article analyzes the emergence and institutionalization of sexology as a science and profession in Portugal, identifying relevant institutions, actors, and professional practices and discussing its relations and specificities. The analysis begins by contextualizing the emergence of modern Western sexology in order to comprehend the Portuguese case in the international sexology context. The second section describes the social, cultural, and institutional factors that have driven the professionalization of sexology. The third section describes the emergence of Portuguese sexology and its principal historical milestones, institutions, and actors. Finally, the article discusses some implications of this process for the role of sexology as a science and profession. The study reveals the dynamics of national and international processes in the field, in the transition from a holistic perspective of sexology to the hegemony of sexual medicine, and sheds light on its mechanisms of legitimation as a transdisciplinary science of sexuality, suggesting future perspectives. PMID:27598015

  11. The international right to health: state obligations and private actors in the health care system.

    PubMed

    O'Brien, Paula

    2013-09-01

    Most health systems have historically used a mix of public and private actors for financing and delivering care. But the last 30 years have seen many rich and middle-income countries moving to privatise parts of their health care systems. This phenomenon has generated concerns, especially about equitable access to health care. This article examines what the international right to the highest attainable standard of health in Art 12 of the International Covenant on Economic, Social and Cultural Rights says about the obligations of states which use private actors in health care. The article involves a close study of the primary documents of the key institutions responsible for interpreting and promoting Art 12. From this study, the article concludes that in mixed public-private health care systems, states not only retain primary responsibility for fulfilling the right to health but are subject to a range of additional specific responsibilities. PMID:24218792

  12. Daily Associations Among Self-control, Heavy Episodic Drinking, and Relationship Functioning: An Examination of Actor and Partner Effects

    PubMed Central

    Crane, Cory A.; Testa, Maria; Derrick, Jaye L.; Leonard, Kenneth E.

    2014-01-01

    An emerging literature suggests that temporary deficits in the ability to inhibit impulsive urges may be proximally associated with intimate partner aggression. The current study examined the experience of alcohol use and the depletion of self-control in the prediction of relationship functioning. Daily diary data collected from 118 heterosexual couples were analyzed using parallel multi-level Actor Partner Interdependence Models to assess the effects of heavy episodic drinking and depletion of self-control across partners on outcomes of participant-reported daily arguing with and anger toward an intimate partner. Heavy episodic drinking among actors predicted greater arguing but failed to interact with either actor or partner depletion. We also found that greater arguing was reported on days of high congruent actor and partner depletion. Both actor and partner depletion, as well as their interaction, predicted greater partner-specific anger. Greater partner-specific anger was generally reported on days of congruent actor and partner depletion, particularly on days of high partner depletion. The current results highlight the importance of independently assessing partner effects (i.e., depletion of self-control), which interact dynamically with disinhibiting actor effects, in the prediction of daily adverse relationship functioning. Results offer further support for the development of prospective individualized and couples-based interventions for partner conflict. PMID:24700558

  13. Inferring the size of a goal object from an actor's grasping movement in 6- and 9-month-old infants.

    PubMed

    Daum, Moritz M; Vuori, Maria T; Prinz, Wolfgang; Aschersleben, Gisa

    2009-11-01

    The present study applied a preferential looking paradigm to test whether 6- and 9-month old infants are able to infer the size of a goal object from an actor's grasping movement. The target object was a cup with the handle rotated either towards or away from the actor. In two experiments, infants saw the video of an actor's grasping movement towards an occluded target object. The aperture size of the actor's hand was varied as between-subjects factor. Subsequently, two final states of the grasping movement were presented simultaneously with the occluder being removed. In Experiment 1, the expected final state showed the actor's hand holding a cup in a way that would be expected after the performed grasping movement. In the unexpected final state, the actor's hand held the cup at the side which would be unexpected after the performed grasping movement. Results show that 6- as well as 9-month-olds looked longer at the unexpected than at the expected final state. Experiment 2 excluded an alternative explanation of these findings, namely that the discrimination of the final states was due to geometrical familiarity or novelty of the final states. These findings provide evidence that infants are able to infer the size of a goal object from the aperture size of the actor's hand during the grasp. PMID:19840041

  14. The Empathy Enigma: Does It Still Exist? Comparison of Empathy Using Students and Standardized Actors.

    PubMed

    Ward, Julia

    2016-01-01

    Empathy is at the heart of all nurse-patient interactions. Yet empathy often declines during students' nursing education. Nurse educators are challenged to find ways to offset this decline. A mixed-methods research design was used to assess whether an educational intervention using standardized actors influenced nursing student empathy. The results suggest that the educational intervention holds potential for improving empathy in nursing students. PMID:26779692

  15. Forest biodiversity monitoring for REDD+: a case study of actors' views in Peru.

    PubMed

    Entenmann, Steffen K; Kaphegyi, Thomas A M; Schmitt, Christine B

    2014-02-01

    The climate change mitigation mechanism Reducing Emissions from Deforestation and Forest Degradation in developing countries (REDD+) is currently being negotiated under the United Nations Framework Convention on Climate Change (UNFCCC). Integrating biodiversity monitoring into REDD+ facilitates compliance with the safeguards stipulated by the UNFCCC to exclude environmental risks. Interviews with actors engaged in REDD+ implementation and biodiversity conservation at the national and sub-national level in Peru (n = 30) and a literature review (n = 58) were conducted to pinpoint constraints and opportunities for monitoring effects of REDD+ management interventions on biodiversity, and to identify relevant biodiversity data and indicators. It was found that particularly sub-national actors, who were frequently involved in REDD+ pilot projects, acknowledge the availability of biodiversity data. Actors at both the national and sub-national levels, however, criticized data gaps and data being scattered across biodiversity research organizations. Most of the literature reviewed (78 %) included indicators on the state of certain biodiversity aspects, especially mammals. Indicators for pressure on biodiversity, impacts on environmental functions, or policy responses to environmental threats were addressed less frequently (31, 21, and 10 %, respectively). Integrating biodiversity concerns in carbon monitoring schemes was considered to have potential, although few specific examples were identified. The involvement of biodiversity research organizations in sub-national REDD+ activities enhances monitoring capacities. It is discussed how improvements in collaboration among actors from the project to the national level could facilitate the evaluation of existing information at the national level. Monitoring changes in ecosystem services may increase the ecological and socioeconomic viability of REDD+. PMID:24178126

  16. Forest Biodiversity Monitoring for REDD+: A Case Study of Actors' Views in Peru

    NASA Astrophysics Data System (ADS)

    Entenmann, Steffen K.; Kaphegyi, Thomas A. M.; Schmitt, Christine B.

    2014-02-01

    The climate change mitigation mechanism Reducing Emissions from Deforestation and Forest Degradation in developing countries (REDD+) is currently being negotiated under the United Nations Framework Convention on Climate Change (UNFCCC). Integrating biodiversity monitoring into REDD+ facilitates compliance with the safeguards stipulated by the UNFCCC to exclude environmental risks. Interviews with actors engaged in REDD+ implementation and biodiversity conservation at the national and sub-national level in Peru ( n = 30) and a literature review ( n = 58) were conducted to pinpoint constraints and opportunities for monitoring effects of REDD+ management interventions on biodiversity, and to identify relevant biodiversity data and indicators. It was found that particularly sub-national actors, who were frequently involved in REDD+ pilot projects, acknowledge the availability of biodiversity data. Actors at both the national and sub-national levels, however, criticized data gaps and data being scattered across biodiversity research organizations. Most of the literature reviewed (78 %) included indicators on the state of certain biodiversity aspects, especially mammals. Indicators for pressure on biodiversity, impacts on environmental functions, or policy responses to environmental threats were addressed less frequently (31, 21, and 10 %, respectively). Integrating biodiversity concerns in carbon monitoring schemes was considered to have potential, although few specific examples were identified. The involvement of biodiversity research organizations in sub-national REDD+ activities enhances monitoring capacities. It is discussed how improvements in collaboration among actors from the project to the national level could facilitate the evaluation of existing information at the national level. Monitoring changes in ecosystem services may increase the ecological and socioeconomic viability of REDD+.

  17. [Status quo and potential of health services research: the perspective of Bavarian actors].

    PubMed

    Hollederer, A; Voigtländer, S; Wildner, M; Zapf, A; Zellner, A

    2015-03-01

    In 2011, the Bavarian Parliament decided to advance health services research (HSR) in Bavaria by bundling scientific competencies in a State Working Group and integrating other actors in it. The establishment of such a State Working Group "Health Services Research" -(LAGeV) together with members from science, health care and politics followed in 2012. The objective of this study is to identify the status quo of HSR in Bavaria including its determinants and potential for development based on the actors' perspective.After the inaugural meeting a semi-structured questionnaire was sent to all 36 members from 28 organisations. Items comprise information on the respondent's background as well as status quo, future topics and potential for development of HSR in Bavaria.27 members took part in the survey, resulting in a response rate of 75.0%. Satisfaction of actors with the status quo of HSR is rather low, especially regarding the effectiveness of policy advice. Researchers and health care providers are also not much satisfied with the HSR environment. For the future of HSR, respondents prioritise the topics interface and networking research, followed by innovative care concepts, care for patients with multiple or chronic conditions as well as evaluation of innovations, processes and technologies. Potential for development and thus improvement of care is primarily seen in the abolishment of existing constraints by an overall HSR concept (including selective research promotion), networking and cooperation, research funding as well as improving the interface between politics and science. Respondents assess the benefit of an increased networking within the LAGeV as high.Status quo of HSR in Bavaria is not very satisfactory. The survey reveals important constraints as well as promoting factors based on the viewpoints of different groups of actors. It also prioritises future HSR topics and identifies potential for development, which are important for the LAGeV. The findings

  18. Modelling the Impact of Human Actors on Groundwater Resources under Conditions of Climate Change

    NASA Astrophysics Data System (ADS)

    Barthel, R.; Reichenau, T. G.; Krimly, T.; Dabbert, S.; Schneider, K.; Mauser, W.; Hennicker, R.

    2012-12-01

    Water resources, activities of human actors and climate change are related in many different and complex ways because of the existence of and strong interactions between various influencing factors, including those that are natural-environmental and socio-economic. The GLOWA-Danube research cooperation has developed the integrated simulation system DANUBIA to simulate water-related influences of global change in different spatial and temporal contexts. DANUBIA is a modular system comprised of 17 dynamically-coupled, process-based model components and a framework which controls the interaction of these components with respect to space and time. This contribution describes approaches and capabilities of DANUBIA with regard to the simulation of global change effects on human decisions in water related fields with a focus on agriculture and groundwater. In agriculture, market prices and legislation can be equally or even more important than water availability in determining farmers' behavior and thus in determining the agricultural impact on water resources quantity and quality. The DANUBIA simulation framework and the associated DeepActor-framework for simulation of decision-making by human actors are presented together with the model components which are most relevant to the interactions between agriculture and groundwater. The approach for developing combination climate and socio-economic scenarios is explained. Exemplary scenario results are shown for the Upper Danube Catchment in Southern Germany. References Barthel, R., Janisch, S., N. Schwarz, A. Trifkovic, D. Nickel, C. Schulz, W. Mauser (2008): An integrated modelling framework for simulating regional-scale actor responses to global change in the water domain. Environmental Modelling and Software, 23, 1095-1121 (doi:10.1016/j.envsoft.2008.02.004) Barthel, R., Reichenau T., Krimly, T., Dabbert, S., Schneider, K., Mauser, W. (2012) Integrated modeling of climate change impacts on agriculture and groundwater

  19. Virtual actors and avatars in a flexible user-determined-scenario environment

    SciTech Connect

    Shawver, D.M.

    1997-02-01

    VRaptor, a VR system for situational training that uses trainer-defined scenarios is described. The trainee is represented by an avatar; the rest of the virtual world is populated by virtual actors, which are under the control of trainer-defined scripts. The scripts allow reactive behaviors, but the trainer can control the overall scenario. This type of training system may be very useful in supplementing physical training.

  20. Finding a voice. Like individuals, organizations are moral speakers and actors.

    PubMed

    Ozar, David T

    2006-01-01

    Though "good people' are important for the life of any organization, it is a myth to think that enough good people will make for a good organization. To break free of this myth, a health care organization, which is made up of numerous persons and groups, ought to be regarded as a single, unitary actor in society. When seen as a single actor, the organization's systems for carrying out its mission can be better assessed and improved if necessary. If the organization's systems are not functioning as they should, then even good people will be hindered in their efforts. It can be said, therefore, that organizational ethics takes seriously the idea that every Catholic health care organization is a moral actor needing to reflect carefully on what it does in relation to its employees, leaders, and the outside community. In an environment where the organization's actions are reflected upon, and its character is carefully and continually shaped according to its mission, individual persons in that organization will be better equipped for making and carrying out good decisions that are aligned with that same regard for the mission. PMID:17086792

  1. Acoustic changes in student actors' voices after 12 months of training.

    PubMed

    Walzak, Peta; McCabe, Patricia; Madill, Cate; Sheard, Christine

    2008-05-01

    This study was to evaluate acoustic changes in student actors' voices after 12 months of actor training. The design used was a longitudinal study. Eighteen students enrolled in an Australian tertiary 3-year acting program (nine male and nine female) were assessed at the beginning of their acting course and again 12 months later using a questionnaire, interview, maximum phonation time (MPT), reading, spontaneous speaking, sustained phonation tasks, and a pitch range task. Samples were analyzed for MPT, fundamental frequency across tasks, pitch range for speaking and reading, singing pitch range, noise-to-harmonic ratio, shimmer, and jitter. After training, measures of shimmer significantly increased for both male and female participants. Female participants' pitch range significantly increased after training, with a significantly lower mean frequency for their lowest pitch. The finding of limited or negative changes for some measures indicate that further investigation is required into the long-term effects of actor voice training and which parameters of voicing are most targeted and valued in training. Particular investigation into the relationship between training targets and outcomes could more reliably inform acting programs about changes in teaching methodologies. Further research into the relationship between specific training techniques, physiological changes, and vocal changes may also provide information on implementing more evidence-based training methods. PMID:17512170

  2. Experiential learning in nursing consultation education via clinical simulation with actors: action research.

    PubMed

    de Oliveira, Saionara Nunes; do Prado, Marta Lenise; Kempfer, Silvana Silveira; Martini, Jussara Gue; Caravaca-Morera, Jaime Alonso; Bernardi, Mariely Carmelina

    2015-02-01

    This was an action research study conducted during an undergraduate nursing course. The objective was to propose and implement experiential learning for nursing consultation education using clinical simulation with actors. The 4 steps of action research were followed: planning, action, observation and reflection. Three nursing undergraduate students participated in the study. Data were collected in May and July 2013 via participant comments and interviews and were analyzed in accordance with the operative proposal for qualitative data analysis. Planning included constructing and validating the clinical guides, selecting and training the actors, organizing and preparing the scenario and the issuing invitations to the participants. The action was carried out according to Kolb's (1984) 4 stages of learning cycles: Concrete Experience, Reflective Observation, Abstract Conceptualization and Active Experimentation. Clinical simulation involves different subjects' participation in all stages, and action research is a method that enables the clinical stimulation to be implemented. It must be guided by clear learning objectives and by a critical pedagogy that encourages critical thinking in students. Using actors and a real scenario facilitated psychological fidelity, and debriefing was the key moment of the reflective process that facilitated the integral training of students through experiential learning. PMID:25563657

  3. Humanoids Learning to Walk: A Natural CPG-Actor-Critic Architecture.

    PubMed

    Li, Cai; Lowe, Robert; Ziemke, Tom

    2013-01-01

    The identification of learning mechanisms for locomotion has been the subject of much research for some time but many challenges remain. Dynamic systems theory (DST) offers a novel approach to humanoid learning through environmental interaction. Reinforcement learning (RL) has offered a promising method to adaptively link the dynamic system to the environment it interacts with via a reward-based value system. In this paper, we propose a model that integrates the above perspectives and applies it to the case of a humanoid (NAO) robot learning to walk the ability of which emerges from its value-based interaction with the environment. In the model, a simplified central pattern generator (CPG) architecture inspired by neuroscientific research and DST is integrated with an actor-critic approach to RL (cpg-actor-critic). In the cpg-actor-critic architecture, least-square-temporal-difference based learning converges to the optimal solution quickly by using natural gradient learning and balancing exploration and exploitation. Futhermore, rather than using a traditional (designer-specified) reward it uses a dynamic value function as a stability indicator that adapts to the environment. The results obtained are analyzed using a novel DST-based embodied cognition approach. Learning to walk, from this perspective, is a process of integrating levels of sensorimotor activity and value. PMID:23675345

  4. Integrated management of natural resources: dealing with ambiguous issues, multiple actors and diverging frames.

    PubMed

    Dewulf, A; Craps, M; Bouwen, R; Taillieu, T; Pahl-Wostl, C

    2005-01-01

    Uncertainty is an increasingly important concern when trying to manage complex systems of interrelated natural resources. Scientific knowledge or necessary information may be lacking or incomplete. Additionally, the multiple and interdependent users of those resources may diverge in defining what really is at stake. When they frame issues in very different ways, ambiguity results, i.e., the existence of two or more equally plausible interpretation possibilities. Environmental management in these conditions implies a shift in attention from solving clearly delineated problems to continuous negotiating and tuning between different actors and expertise domains. This requires dealing with the frame differences in a reciprocal way by mutually acknowledging frames and connecting them. Some or all parties will have to revise, enlarge or reframe the way they relate to the issues and to each other, in order to support mutual understanding and common action. The contribution of experts does not consist then in providing total predictability nor in predefining issues and solutions, but in supporting a joint learning and negotiation process among different actors and in feeding this process with relevant information. Behavioural simulations may play an important function to stimulate multi-actor learning and negotiation processes. PMID:16304943

  5. Creating Inquiry Between Technology Developers and Civil Society Actors: Learning from Experiences Around Nanotechnology.

    PubMed

    Krabbenborg, Lotte

    2016-06-01

    Engaging civil society actors as knowledgeable dialogue partners in the development and governance of emerging technologies is a new challenge. The starting point of this paper is the observation that the design and orchestration of current organized interaction events shows limitations, particularly in the articulation of issues and in learning how to address the indeterminacies that go with emerging technologies. This paper uses Dewey's notion of 'publics' and 'reflective inquiry' to outline ways of doing better and to develop requirements for a more productive involvement of civil society actors. By studying four novel spaces for interaction in the domain of nanotechnology, this paper examines whether and how elements of Dewey's thought are visible and under what conditions. One of the main findings is that, in our society, special efforts are needed in order for technology developers and civil society actors to engage in a joint inquiry on emerging nanotechnology. Third persons, like social scientists and philosophers, play a role in this respect in addition to external input such as empirically informed scenarios and somewhat protected spaces. PMID:26040841

  6. Humanoids Learning to Walk: A Natural CPG-Actor-Critic Architecture

    PubMed Central

    Li, Cai; Lowe, Robert; Ziemke, Tom

    2013-01-01

    The identification of learning mechanisms for locomotion has been the subject of much research for some time but many challenges remain. Dynamic systems theory (DST) offers a novel approach to humanoid learning through environmental interaction. Reinforcement learning (RL) has offered a promising method to adaptively link the dynamic system to the environment it interacts with via a reward-based value system. In this paper, we propose a model that integrates the above perspectives and applies it to the case of a humanoid (NAO) robot learning to walk the ability of which emerges from its value-based interaction with the environment. In the model, a simplified central pattern generator (CPG) architecture inspired by neuroscientific research and DST is integrated with an actor-critic approach to RL (cpg-actor-critic). In the cpg-actor-critic architecture, least-square-temporal-difference based learning converges to the optimal solution quickly by using natural gradient learning and balancing exploration and exploitation. Futhermore, rather than using a traditional (designer-specified) reward it uses a dynamic value function as a stability indicator that adapts to the environment. The results obtained are analyzed using a novel DST-based embodied cognition approach. Learning to walk, from this perspective, is a process of integrating levels of sensorimotor activity and value. PMID:23675345

  7. Stuck in the middle?: A perspective on ongoing pro-competitive reforms in Dutch mental health care.

    PubMed

    Westra, Daan; Wilbers, Gloria; Angeli, Federica

    2016-04-01

    Pro-competitive reforms have been implemented in many Western healthcare systems, of which the Netherlands is a prominent example. While the pro-competitive reforms in the Dutch specialized care sector have drawn considerable academic attention, mental health care is often excluded. However, in line with other segments of specialized care, pro-competitive legislation has formed the core of mental health care reforms, albeit with several notable differences. Ever since mental health services were included in the Health Insurance Act in 2008, the Dutch mental healthcare sector has been in an ongoing state of reform. Numerous major and minor adaptations have continuously altered the services covered by the basic insurance package, the actors responsible for providing and contracting care, and definitions and measurements of quality. Most notably, insurers and municipalities, which are responsible for selectively contracting those providers that offer high value-for-money, seem insensitive to quality aspects. The question whether the Dutch mental health sector has inherited the best or the worst of a competitive and non-competitive system lingers and international policy makers contemplating reforming their mental health sector should take note. PMID:26994866

  8. Application of actor level social characteristic indicator selection for the precursory detection of bullies in online social networks

    NASA Astrophysics Data System (ADS)

    White, Holly M.; Fields, Jeremy; Hall, Robert T.; White, Joshua S.

    2016-05-01

    Bullying is a national problem for families, courts, schools, and the economy. Social, educational, and professional lives of victims are affected. Early detection of bullies mitigates destructive effects of bullying. Our previous research found, given specific characteristics of an actor, actor logics can be developed utilizing input from natural language processing and graph analysis. Given similar characteristics of cyberbullies, in this paper, we create specific actor logics and apply these to a select social media dataset for the purpose of rapid identification of cyberbullying.

  9. Pocahontas: Problematizing the Pro-Social.

    ERIC Educational Resources Information Center

    Aidman, Amy; Reese, Debbie

    The Disney film "Pocahontas" appears to be an attempt to respond to growing cultural diversity, calls for multiculturalism, and strong female role models in the United States. This paper provides an analysis of the film, examining how Disney's claims to the creation of positive, pro-social representations of women and Native Americans in…

  10. Local energy governance in vermont: an analysis of energy system transition strategies and actor capacity

    NASA Astrophysics Data System (ADS)

    Rowse, Tarah

    While global, national, and regional efforts to address climate and energy challenges remain essential, local governments and community groups are playing an increasingly stronger and vital role. As an active state in energy system policy, planning and innovation, Vermont offers a testing ground for research into energy governance at the local level. A baseline understanding of the energy planning and energy organizing activities initiated at the local level can support efforts to foster a transition to a sustainable energy system in Vermont. Following an inductive, applied and participatory approach, and grounded in the fields of sustainability transitions, energy planning, and community energy, this research project identifies conditions for change, including opportunities and challenges, within Vermont energy system decision-making and governance at the local level. The following questions are posed: What are the main opportunities and challenges for sustainable energy development at the town level? How are towns approaching energy planning? What are the triggers that will facilitate a faster transition to alternative energy systems, energy efficiency initiatives, and localized approaches? In an effort to answer these questions two studies were conducted: 1) an analysis of municipal energy plans, and 2) a survey of local energy actors. Study 1 examined Vermont energy planning at the state and local level through a review and comparison of 40 municipal plan energy chapters with the state 2011 Comprehensive Energy Plan. On average, municipal plans mentioned just over half of the 24 high-level strategies identified in the Comprehensive Energy Plan. Areas of strong and weak agreement were examined. Increased state and regional interaction with municipal energy planners would support more holistic and coordinated energy planning. The study concludes that while municipalities are keenly aware of the importance of education and partnerships, stronger policy mechanisms

  11. Opponent actor learning (OpAL): modeling interactive effects of striatal dopamine on reinforcement learning and choice incentive.

    PubMed

    Collins, Anne G E; Frank, Michael J

    2014-07-01

    The striatal dopaminergic system has been implicated in reinforcement learning (RL), motor performance, and incentive motivation. Various computational models have been proposed to account for each of these effects individually, but a formal analysis of their interactions is lacking. Here we present a novel algorithmic model expanding the classical actor-critic architecture to include fundamental interactive properties of neural circuit models, incorporating both incentive and learning effects into a single theoretical framework. The standard actor is replaced by a dual opponent actor system representing distinct striatal populations, which come to differentially specialize in discriminating positive and negative action values. Dopamine modulates the degree to which each actor component contributes to both learning and choice discriminations. In contrast to standard frameworks, this model simultaneously captures documented effects of dopamine on both learning and choice incentive-and their interactions-across a variety of studies, including probabilistic RL, effort-based choice, and motor skill learning. PMID:25090423

  12. 26 CFR 1.1377-1 - Pro rata share.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 11 2011-04-01 2011-04-01 false Pro rata share. 1.1377-1 Section 1.1377-1...) INCOME TAXES (CONTINUED) Small Business Corporations and Their Shareholders § 1.1377-1 Pro rata share. (a) Computation of pro rata shares—(1) In general. For purposes of subchapter S of chapter 1 of the...

  13. 31 CFR 50.93 - Application of pro rata share.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Application of pro rata share. 50.93... PROGRAM Cap on Annual Liability § 50.93 Application of pro rata share. An insurer shall apply the PRLP to determine the pro rata share of each insured loss to be paid by the insurer on all insured losses...

  14. 31 CFR 50.93 - Application of pro rata share.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Application of pro rata share. 50.93... PROGRAM Cap on Annual Liability § 50.93 Application of pro rata share. An insurer shall apply the PRLP to determine the pro rata share of each insured loss to be paid by the insurer on all insured losses...

  15. Cryogenic system for BERLinPro

    NASA Astrophysics Data System (ADS)

    Anders, W.; Hellwig, A.; Knobloch, J.; Pflückhahn, D.; Rotterdam, S.

    2014-01-01

    In 2010 Helmholtz-Zentrum Berlin (HZB) received funding to design and build the Berlin Energy Recovery Linac Project BERLinPro. The goal of this compact Energy recovery linac (ERL) is to develop the accelerator physics and technology required to generate and accelerate a 100-mA, 1-mm mrad emittance electron beam. The BERLinPro know-how can then be transferred to various ERL-based applications. All accelerating RF cavities including the electron source are based on superconducting technology operated at 1.8 K. A Linde L700 helium liquefier is supplying 4.5 K helium. The subatmospheric pressure of 16 mbar of the helium bath of the cavities will be achieved by pumping with a set of cold compressors and warm vacuum pumps. While the L700 is already in operating, the 1.8 K system and the helium transfer system are in design phase.

  16. [Radiation Anticarcinogenesis by Thiazolidine Pro-drug

    NASA Technical Reports Server (NTRS)

    Warters, Raymond L.; Roberts, Jeanette C.; Fain, Heidi

    1999-01-01

    The original goal of this work was to determine the capacity of selected aminothiols to modulate radiation induced cytotoxicity, mutagenesis and carcinogenesis in a human mammary epithelial cell line. The conclusions from this work are that WR-1065 is the "gold standard" for protection against radiation induced cytotoxicity, mutagenesis and carcinogenesis. While a potent radiation protector, WR-1065 is cytotoxic in vitro and in vivo. Our rationale for a study of the thiazolidine pro-drugs was that these compounds are neither toxic in vitro or in vivo. The results obtained during this funding period indicate that the thiazolidine pro-drugs are as potent as WR-1065 as protectors against radiation induced mutation induction, and thus presumably against radiation induced carcinogenesis. Our results indicate that the thiazolidine prodrugs are excellent candidates to test as non-toxic anticarcinogens for protecting astronauts from cancer induction during space travel.

  17. Cryogenic system for BERLinPro

    SciTech Connect

    Anders, W.; Hellwig, A.; Knobloch, J.; Pflückhahn, D.; Rotterdam, S.

    2014-01-29

    In 2010 Helmholtz-Zentrum Berlin (HZB) received funding to design and build the Berlin Energy Recovery Linac Project BERLinPro. The goal of this compact Energy recovery linac (ERL) is to develop the accelerator physics and technology required to generate and accelerate a 100-mA, 1-mm mrad emittance electron beam. The BERLinPro know-how can then be transferred to various ERL-based applications. All accelerating RF cavities including the electron source are based on superconducting technology operated at 1.8 K. A Linde L700 helium liquefier is supplying 4.5 K helium. The subatmospheric pressure of 16 mbar of the helium bath of the cavities will be achieved by pumping with a set of cold compressors and warm vacuum pumps. While the L700 is already in operating, the 1.8 K system and the helium transfer system are in design phase.

  18. The ProSeal laryngeal mask airway.

    PubMed

    Brimacombe, Joseph; Keller, Christian

    2002-12-01

    The ProSeal LMA is a major advance over the Classic LMA because of the following reasons: it allows ventilation at much higher airway pressures; it protects the lungs from aspiration and the stomach from gastric insufflation; it facilitates passage of a gastric tube and monitoring devices into the esophagus; it can be inserted like the Classic or Intubating LMA; it has its own built-in bite block; malposition is detected more readily; and, through use of techniques such as gum elastic bougie-guided insertion, correct positioning is almost guaranteed. The ProSeal can be considered a replacement device for the Classic LMA, but the Flexible LMA is still preferable for most intraoral procedures, and the Intubating LMA is still preferable whenever intubation is required. Limitations are that it is slightly more difficult to insert and requires more careful thought to use optimally. PMID:12512267

  19. Actor groups, related needs, and challenges at the climate downscaling interface

    NASA Astrophysics Data System (ADS)

    Rössler, Ole; Benestad, Rasmus; Diamando, Vlachogannis; Heike, Hübener; Kanamaru, Hideki; Pagé, Christian; Margarida Cardoso, Rita; Soares, Pedro; Maraun, Douglas; Kreienkamp, Frank; Christodoulides, Paul; Fischer, Andreas; Szabo, Peter

    2016-04-01

    At the climate downscaling interface, numerous downscaling techniques and different philosophies compete on being the best method in their specific terms. Thereby, it remains unclear to what extent and for which purpose these downscaling techniques are valid or even the most appropriate choice. A common validation framework that compares all the different available methods was missing so far. The initiative VALUE closes this gap with such a common validation framework. An essential part of a validation framework for downscaling techniques is the definition of appropriate validation measures. The selection of validation measures should consider the needs of the stakeholder: some might need a temporal or spatial average of a certain variable, others might need temporal or spatial distributions of some variables, still others might need extremes for the variables of interest or even inter-variable dependencies. Hence, a close interaction of climate data providers and climate data users is necessary. Thus, the challenge in formulating a common validation framework mirrors also the challenges between the climate data providers and the impact assessment community. This poster elaborates the issues and challenges at the downscaling interface as it is seen within the VALUE community. It suggests three different actor groups: one group consisting of the climate data providers, the other two groups being climate data users (impact modellers and societal users). Hence, the downscaling interface faces classical transdisciplinary challenges. We depict a graphical illustration of actors involved and their interactions. In addition, we identified four different types of issues that need to be considered: i.e. data based, knowledge based, communication based, and structural issues. They all may, individually or jointly, hinder an optimal exchange of data and information between the actor groups at the downscaling interface. Finally, some possible ways to tackle these issues are

  20. Performance evaluation of a simulated data-flow computer with low-resolution actors

    SciTech Connect

    Gaudiot, J.L.; Ercegovac, M.D.

    1985-11-01

    In the ambition to go beyond a single-processor architecture, to enhance programmability, and to take advantage of the power brought by VLSI devices, data-flow systems and languages were devised. Indeed, due to their functional semantics, these languages offer promise in the area of multiprocessor systems design and will possibly enable the development of computers comprising large numbers of processors with a corresponding increase in performance. Several important design problems have to be surmounted and are described here. The authors thus present a ''variable-resolution'' scheme, where the level of primitives can be selected so that the overhead due to the data-flow mode of operation is reduced. A deterministic simulation of a data-flow machine with a variable number of processing elements was undertaken and is described here. The tests were performed using various program structures such as directed acyclic graphs, vector operations, and array handling. The performance results observed confirm the advantage of actors with variable size and indicate the presence of a trade-off between overhead control and the need to control parallelism in the program. The authors also look at some of the communication issues and examine the effect of several interconnection networks (dual counter-rotating rings, daisy chain, and optimal double loop network) on the performance. It is shown how increasing communication costs induce a performance degradation that can be masked when the size of the basic data-flow actor is increased. The associative memory cycle time is also changed with similar conclusions. Finally, the lower-resolution scheme is applied to the array handling case; the observations confirm the advantage of a more complex actor at the array level.

  1. Is Brain Activity during Action Observation Modulated by the Perceived Fairness of the Actor?

    PubMed Central

    Gazzola, Valeria; Keysers, Christian

    2016-01-01

    Perceiving other people’s actions triggers activity in premotor and parietal areas, brain areas also involved in executing and sensing our own actions. Paralleling this phenomenon, observing emotional states (including pain) in others is associated with activity in the same brain areas as activated when experiencing similar emotions directly. This emotion perception associated activity has been shown to be affected by the perceived fairness of the actor, and in-group membership more generally. Here, we examine whether action observation associated brain activity is also affected by the perceived social fairness of the actors. Perceived fairness was manipulated using an alternating iterated Prisoner’s Dilemma game between the participant and two confederates, one of whom played fairly and the other unfairly. During fMRI scanning the participants watched movies of the confederates performing object-directed hand actions, and then performed hand actions themselves. Mass-univariate analysis showed that observing the actions triggered robust activation in regions associated with action execution, but failed to identify a strong modulation of this activation based on perceived fairness. Multivariate pattern analysis, however, identified clusters potentially carrying information about the perceived fairness of the actor in the middle temporal gyrus, left postcentral gyrus, right inferior parietal lobule, right middle cingulate cortex, right angular gyrus, and right superioroccipital gyrus. Despite being identified by a whole-brain searchlight analysis (and so without anatomical restriction), these clusters fall into areas frequently associated with action observation. We conclude that brain activity during action observation may be modulated by perceived fairness, but such modulation is subtle; robust activity is associated with observing the actions of both fair and unfair individuals. PMID:26820995

  2. Is Brain Activity during Action Observation Modulated by the Perceived Fairness of the Actor?

    PubMed

    Etzel, Joset A; Valchev, Nikola; Gazzola, Valeria; Keysers, Christian

    2016-01-01

    Perceiving other people's actions triggers activity in premotor and parietal areas, brain areas also involved in executing and sensing our own actions. Paralleling this phenomenon, observing emotional states (including pain) in others is associated with activity in the same brain areas as activated when experiencing similar emotions directly. This emotion perception associated activity has been shown to be affected by the perceived fairness of the actor, and in-group membership more generally. Here, we examine whether action observation associated brain activity is also affected by the perceived social fairness of the actors. Perceived fairness was manipulated using an alternating iterated Prisoner's Dilemma game between the participant and two confederates, one of whom played fairly and the other unfairly. During fMRI scanning the participants watched movies of the confederates performing object-directed hand actions, and then performed hand actions themselves. Mass-univariate analysis showed that observing the actions triggered robust activation in regions associated with action execution, but failed to identify a strong modulation of this activation based on perceived fairness. Multivariate pattern analysis, however, identified clusters potentially carrying information about the perceived fairness of the actor in the middle temporal gyrus, left postcentral gyrus, right inferior parietal lobule, right middle cingulate cortex, right angular gyrus, and right superioroccipital gyrus. Despite being identified by a whole-brain searchlight analysis (and so without anatomical restriction), these clusters fall into areas frequently associated with action observation. We conclude that brain activity during action observation may be modulated by perceived fairness, but such modulation is subtle; robust activity is associated with observing the actions of both fair and unfair individuals. PMID:26820995

  3. Cognitive Obstacles to Pro-Vaccination Beliefs.

    PubMed

    Miton, Helena; Mercier, Hugo

    2015-11-01

    Two frameworks--cultural attraction theory and epistemic vigilance--predict a cultural disadvantage for counter-intuitive beliefs. We review several cognitive mechanisms that conspire to render pro-vaccination beliefs counter-intuitive. Trust and argumentation can spread counter-intuitive beliefs, but only under some conditions. We discuss the hurdles that trust and argumentation face in the case of vaccination. PMID:26522341

  4. Some problems with pro-competition reforms.

    PubMed

    Agich, G J; Begley, C E

    1985-01-01

    As the search for effective cost-containment policies continues, health care reform along pro-competition lines has gained considerable backing in the United States. By offering market competition to achieve allocational efficiency and vouchers and tax credits to achieve distributional equity, pro-competition reforms appear to satisfy what many believed were incommensurable goals. A critical review of this strategy reveals two practical difficulties, however. The first concerns the ambiguity arising from the proposals' reliance on the concept of equal access to some basic level of health care as its distributional objective and the second concerns the ethical dilemma arising from the proposals' reliance on physicians as rationers of health care. In considering the distributional goal of guaranteeing access to a basic minimum of health care, we argue that, despite its theoretical attractiveness, there exists no acceptable way of determining or justifying its content, and without a clear definition of the basic minimum there is no guarantee that any equity objective will be achieved under the pro-competition strategy. With regard to the use of physicians and other providers as society's gatekeepers, we point out that this role is in direct conflict with traditional responsibilities that patients expect providers to assume. Requiring doctors to ration services in response to market incentives may further erode the trust relationship between physicians and patients, and clearly puts the more seriously ill at a disadvantage. PMID:4059946

  5. Calibrating the Prominence Magnetometer (ProMag)

    NASA Astrophysics Data System (ADS)

    Fox, Lewis; Casini, R.

    2013-07-01

    The Prominence Magnetometer (ProMag) is a dual-channel, dual-beam, slit-scanning, full Stokes spectro-polarimeter designed by the High Altitude Observatory at the National Center for Atmospheric Research (HAO/NCAR) for the study of the magnetism of solar prominences and filaments. It was deployed in August 2009 at the 40 cm coronagraph of the Evans Solar Facility (ESF) of the National Solar Observatory on Sacramento Peak (NSO/SP). In its standard mode of operation it acquires spectro-polarimetric maps of solar targets simultaneously in the two chromospheric lines of He I at 587.6 nm and 1083.0 nm. Since August 2011 ProMag has operated in “patrol mode” with a dedicated observer. We aim to routinely measure the vector magnetic field in prominences. The electro-optic modulator and polarization analyzer are integrated into a single mechanical unit located at the coude feed of the telescope. This location was necessary for proper co-alignment of the dual beams, but complicates the precise polarimeter calibration necessary to achieve the sensitivity required for prominence measurements (< 10^-3). At this sensitivity, small variations in optical alignment can become significant. We present a calibration method for ProMag, using a polarizer and retarder at coronagraph prime focus. Calibrations are recorded before and after observations. We discuss the success of this method and its limitations.

  6. Perl Embedded in PTC's Pro/ENGINEER, Version 1

    SciTech Connect

    2003-12-22

    Pro-PERL (AKA Pro/PERL) is a Perl extension to the PTC Pro/TOOLKIT API to the PTC Pro/ENGINEER CAD application including an embedded interpreter. It can be used to automate and customize Pro/ENGINEER, create Vendor Neutral Archive (VNA) format files and re-create CAD models from the VNA files. This has applications in sanitizing classified CAD models created in a classified environment for transfer to an open environment, creating template models for modification to finished models by non-expert users, and transfer of design intent data to other modeling technologies.

  7. Perl Embedded in PTC's Pro/ENGINEER, Version 1

    Energy Science and Technology Software Center (ESTSC)

    2003-12-22

    Pro-PERL (AKA Pro/PERL) is a Perl extension to the PTC Pro/TOOLKIT API to the PTC Pro/ENGINEER CAD application including an embedded interpreter. It can be used to automate and customize Pro/ENGINEER, create Vendor Neutral Archive (VNA) format files and re-create CAD models from the VNA files. This has applications in sanitizing classified CAD models created in a classified environment for transfer to an open environment, creating template models for modification to finished models by non-expertmore » users, and transfer of design intent data to other modeling technologies.« less

  8. Potential risks of pro-eating disorder websites.

    PubMed

    Rouleau, Codie R; von Ranson, Kristin M

    2011-06-01

    Although dangers of pro-eating disorder (pro-ED) websites have recently been discussed in the popular press, no integration of research findings on this topic yet exists. After completing a systematic search for peer-reviewed articles about pro-ED websites, we identified three possible risks as themes: operation under the guise of "support," reinforcement of disordered eating, and prevention of help-seeking and recovery. Pro-ED websites tend to be perceived as supportive by users, but instead appear to exacerbate or maintain users' eating disorder symptoms. We discuss research and clinical implications of these dangers. Future research should clarify how specific features of pro-ED websites contribute to the development, exacerbation, and maintenance of eating pathology, e.g., by employing experimental techniques and prospective designs with clinical samples and various ages. Despite limited empirical research on the topic, existing findings should prompt clinicians, parents, and researchers to remain vigilant about potential negative influences of pro-ED websites on users. PMID:21272967

  9. BDNF pro-peptide regulates dendritic spines via caspase-3.

    PubMed

    Guo, J; Ji, Y; Ding, Y; Jiang, W; Sun, Y; Lu, B; Nagappan, G

    2016-01-01

    The precursor of brain-derived neurotrophic factor (BDNF) (proBDNF) is enzymatically cleaved, by either intracellular (furin/PC1) or extracellular proteases (tPA/plasmin/MMP), to generate mature BDNF (mBDNF) and its pro-peptide (BDNF pro-peptide). Little is known about the function of BDNF pro-peptide. We have developed an antibody that specifically detects cleaved BDNF pro-peptide, but not proBDNF or mBDNF. Neuronal depolarization elicited a marked increase in extracellular BDNF pro-peptide, suggesting activity-dependent regulation of its extracellular levels. Exposure of BDNF pro-peptide to mature hippocampal neurons in culture dramatically reduced dendritic spine density. This effect was mediated by caspase-3, as revealed by studies with pharmacological inhibitors and genetic knockdown. BDNF pro-peptide also increased the number of 'elongated' mitochondria and cytosolic cytochrome c, suggesting the involvement of mitochondrial-caspase-3 pathway. These results, along with BDNF pro-peptide effects recently reported on growth cones and long-term depression (LTD), suggest that BDNF pro-peptide is a negative regulator of neuronal structure and function. PMID:27310873

  10. Real-time reinforcement learning by sequential Actor-Critics and experience replay.

    PubMed

    Wawrzyński, Paweł

    2009-12-01

    Actor-Critics constitute an important class of reinforcement learning algorithms that can deal with continuous actions and states in an easy and natural way. This paper shows how these algorithms can be augmented by the technique of experience replay without degrading their convergence properties, by appropriately estimating the policy change direction. This is achieved by truncated importance sampling applied to the recorded past experiences. It is formally shown that the resulting estimation bias is bounded and asymptotically vanishes, which allows the experience replay-augmented algorithm to preserve the convergence properties of the original algorithm. The technique of experience replay makes it possible to utilize the available computational power to reduce the required number of interactions with the environment considerably, which is essential for real-world applications. Experimental results are presented that demonstrate that the combination of experience replay and Actor-Critics yields extremely fast learning algorithms that achieve successful policies for non-trivial control tasks in considerably short time. Namely, the policies for the cart-pole swing-up [Doya, K. (2000). Reinforcement learning in continuous time and space. Neural Computation, 12(1), 219-245] are obtained after as little as 20 min of the cart-pole time and the policy for Half-Cheetah (a walking 6-degree-of-freedom robot) is obtained after four hours of Half-Cheetah time. PMID:19523786

  11. Actors and networks in resource conflict resolution under climate change in rural Kenya

    NASA Astrophysics Data System (ADS)

    Ngaruiya, Grace W.; Scheffran, Jürgen

    2016-05-01

    The change from consensual decision-making arrangements into centralized hierarchical chieftaincy schemes through colonization disrupted many rural conflict resolution mechanisms in Africa. In addition, climate change impacts on land use have introduced additional socio-ecological factors that complicate rural conflict dynamics. Despite the current urgent need for conflict-sensitive adaptation, resolution efficiency of these fused rural institutions has hardly been documented. In this context, we analyse the Loitoktok network for implemented resource conflict resolution structures and identify potential actors to guide conflict-sensitive adaptation. This is based on social network data and processes that are collected using the saturation sampling technique to analyse mechanisms of brokerage. We find that there are three different forms of fused conflict resolution arrangements that integrate traditional institutions and private investors in the community. To effectively implement conflict-sensitive adaptation, we recommend the extension officers, the council of elders, local chiefs and private investors as potential conduits of knowledge in rural areas. In conclusion, efficiency of these fused conflict resolution institutions is aided by the presence of holistic resource management policies and diversification in conflict resolution actors and networks.

  12. Actor-critic-based optimal tracking for partially unknown nonlinear discrete-time systems.

    PubMed

    Kiumarsi, Bahare; Lewis, Frank L

    2015-01-01

    This paper presents a partially model-free adaptive optimal control solution to the deterministic nonlinear discrete-time (DT) tracking control problem in the presence of input constraints. The tracking error dynamics and reference trajectory dynamics are first combined to form an augmented system. Then, a new discounted performance function based on the augmented system is presented for the optimal nonlinear tracking problem. In contrast to the standard solution, which finds the feedforward and feedback terms of the control input separately, the minimization of the proposed discounted performance function gives both feedback and feedforward parts of the control input simultaneously. This enables us to encode the input constraints into the optimization problem using a nonquadratic performance function. The DT tracking Bellman equation and tracking Hamilton-Jacobi-Bellman (HJB) are derived. An actor-critic-based reinforcement learning algorithm is used to learn the solution to the tracking HJB equation online without requiring knowledge of the system drift dynamics. That is, two neural networks (NNs), namely, actor NN and critic NN, are tuned online and simultaneously to generate the optimal bounded control policy. A simulation example is given to show the effectiveness of the proposed method. PMID:25312944

  13. The actor-critic learning is behind the matching law: matching versus optimal behaviors.

    PubMed

    Sakai, Yutaka; Fukai, Tomoki

    2008-01-01

    The ability to make a correct choice of behavior from various options is crucial for animals' survival. The neural basis for the choice of behavior has been attracting growing attention in research on biological and artificial neural systems. Alternative choice tasks with variable ratio (VR) and variable interval (VI) schedules of reinforcement have often been employed in studying decision making by animals and humans. In the VR schedule task, alternative choices are reinforced with different probabilities, and subjects learn to select the behavioral response rewarded more frequently. In the VI schedule task, alternative choices are reinforced at different average intervals independent of the choice frequencies, and the choice behavior follows the so-called matching law. The two policies appear robustly in subjects' choice of behavior, but the underlying neural mechanisms remain unknown. Here, we show that these seemingly different policies can appear from a common computational algorithm known as actor-critic learning. We present experimentally testable variations of the VI schedule in which the matching behavior gives only a suboptimal solution to decision making and show that the actor-critic system exhibits the matching behavior in the steady state of the learning even when the matching behavior is suboptimal. However, it is found that the matching behavior can earn approximately the same reward as the optimal one in many practical situations. PMID:18045007

  14. Brain-Machine Interface control of a robot arm using actor-critic rainforcement learning.

    PubMed

    Pohlmeyer, Eric A; Mahmoudi, Babak; Geng, Shijia; Prins, Noeline; Sanchez, Justin C

    2012-01-01

    Here we demonstrate how a marmoset monkey can use a reinforcement learning (RL) Brain-Machine Interface (BMI) to effectively control the movements of a robot arm for a reaching task. In this work, an actor-critic RL algorithm used neural ensemble activity in the monkey's motor cortext to control the robot movements during a two-target decision task. This novel approach to decoding offers unique advantages for BMI control applications. Compared to supervised learning decoding methods, the actor-critic RL algorithm does not require an explicit set of training data to create a static control model, but rather it incrementally adapts the model parameters according to its current performance, in this case requiring only a very basic feedback signal. We show how this algorithm achieved high performance when mapping the monkey's neural states (94%) to robot actions, and only needed to experience a few trials before obtaining accurate real-time control of the robot arm. Since RL methods responsively adapt and adjust their parameters, they can provide a method to create BMIs that are robust against perturbations caused by changes in either the neural input space or the output actions they generate under different task requirements or goals. PMID:23366831

  15. An Actor-Critic architecture and simulator for goal-directed Brain-Machine Interfaces.

    PubMed

    Mahmoudi, Babak; Principe, Jose C; Sanchez, Justin C

    2009-01-01

    The Perception-Action Cycle (PAC) is a central component of goal-directed behavior because it links internal percepts with external outcomes in the environment. Using inspiration from the PAC, we are developing a Brain-Machine Interface control architecture that utilizes both motor commands and goal information directly from the brain to navigate to novel targets in an environment. An Actor-Critic algorithm was selected for decoding the neural motor commands because it is a PAC-based computational framework where the perception component is implemented in the critic structure and the actor is responsible for taking actions. We develop in this work a biologically realistic simulator to analyze the performance of the decoder in terms of convergence and target acquisition. Experience from the simulator will guide parameter selection and assist in understanding the architecture before animal experiments. By varying the signal to noise ratio of the neural input and error signal, we were able to demonstrate how the learning rate and initial conditions affect a motor control target selection task. In this framework, the naïve decoder was able to reach targets in the presence of noise in the error signal and neural motor command with 98% accuracy. PMID:19963795

  16. Actor coalitions and implementation in strategic delta planning: Opening the Haringvliet sluices in the Netherlands

    NASA Astrophysics Data System (ADS)

    Vermoolen, Myrthe; Hermans, Leon

    2016-04-01

    The sustained development of urbanizing deltas is influenced by natural and societal processes. These processes are characterized by their long time span, in which conflicting interests of different stakeholders have to be reconciled. Reaching consent between actors is a challenge itself, but maintaining this consent throughout different stages of strategic planning - from advocacy and agenda setting to implementation - over these long periods of time is even more difficult. The implementation stage still includes many different actors involved, some of which are different than the ones who agreed before, due to both the long run of the strategic delta planning, and to a shift of tasks and responsibilities. Thus, implementation of strategic plans often features delays, deviations of agreed plans and unintended outcomes. A key question therefore is how coalition dynamics in (pre-)planning stages influence and are influenced by the coalition dynamics during implementation. The different stages in strategic planning are often studied from either a plan formulation or an implementation perspective, but the connection between the two proves an important bottleneck for strategic planning in deltas. For instance, many building with nature solutions are still in their pilot-phase, and their upscaling can profit from lessons concerning past implementation efforts. The proposed contribution will use the case of the management of the Dutch Haringvliet sluices and the decision ('Kierbesluit') in 2000 to put these sluices ajar, to study the link between the different strategic delta planning stages and the role of the formation and change of actor coalitions herein. With the completion of the Haringvliet dam with outlet sluices in 1970, the Haringvliet estuary of the rivers Rhine and Meuse was closed off from the sea, creating a fresh water lake. This was done to make the Dutch Southwest delta safe from flooding, and had positive effects for agricultural water supply and

  17. The pro-adhesive and pro-survival effects of glucocorticoid in human ovarian cancer cells.

    PubMed

    Yin, Lijuan; Fang, Fang; Song, Xinglei; Wang, Yan; Huang, Gaoxiang; Su, Jie; Hui, Ning; Lu, Jian

    2016-07-01

    Cell adhesion to extracellular matrix (ECM) is controlled by multiple signaling molecules and intracellular pathways, and is pivotal for survival and growth of cells from most solid tumors. Our previous works demonstrated that dexamethasone (DEX) significantly enhances cell adhesion and cell resistance to chemotherapeutics by increasing the levels of integrin β1, α4, and α5 in human ovarian cancer cells. However, it is unclear whether the components of ECM or other membrane molecules are also involved in the pro-adhesive effect of DEX in ovarian cancer cells. In this study, we demonstrated that the treatment of cells with DEX did not change the expression of collagens (I, III, and IV), laminin, CD44, and its principal ligand hyaluronan (HA), but significantly increased the levels of intracellular and secreted fibronectin (FN). Inhibiting the expression of FN with FN1 siRNA or blocking CD44, another FN receptor, with CD44 blocking antibody significantly attenuated the pro-adhesion of DEX, indicating that upregulation of FN mediates the pro-adhesive effect of DEX by its interaction with CD44 besides integrin β1. Moreover, DEX significantly enhanced cell resistance to the chemotherapeutic agent paclitaxel (PTX) by activating PI-3K-Akt pathway. Finally, we found that DEX also significantly upregulated the expression of MUC1, a transmembrane glycoprotein. Inhibiting the expression of MUC1 with MUC1 siRNA significantly attenuated the DEX-induced effects of pro-adhesion, Akt-activation, and pro-survival. In conclusion, these results provide new data that upregulation of FN and MUC1 by DEX contributes to DEX-induced pro-adhesion and protects ovarian cancer cells from chemotherapy. PMID:27151574

  18. The Establishment of Marine Protected Areas in Senegal: Untangling the Interactions Between International Institutions and National Actors

    NASA Astrophysics Data System (ADS)

    Ferraro, Gianluca; Brans, Marleen; Dème, Moustapha; Failler, Pierre

    2011-04-01

    International institutions, understood as sets of rules contained in international agreements, are aimed at orienting national governments towards specific policy options. Nevertheless, they can determine a change in national policies and practices only if states are willing and capable of incorporating international obligations into their national legislations and ensuring their application and enforcement in areas that follow completely under national jurisdiction. The establishment of marine protected areas promoted by international agreements as a tool for the protection of marine resources represents an interesting case for revealing the complex interactions between international institutions and national actors. Particularly, the establishment of these areas in Senegal shows the salience of domestic constellations of actors who may support or undercut national commitments to international regimes: political elites, bureaucracies, the general public and target groups. By anchoring the empirical analysis to an actor-centred institutionalist perspective, the article explains how dynamic constellations of actors can distort the penetration of international objectives in the national policy framework. Different constellations of national actors can indeed bend international institutions at different moments: during the formulation of a new law in line with international obligations; in the definition of its implementation framework; and in the enforcement of national policies.

  19. Educational Opportunities in Pro-Am Collaboration

    NASA Astrophysics Data System (ADS)

    Fienberg, R. T.; Stencel, R. E.

    2006-08-01

    While many backyard stargazers take up the hobby just for fun, many others are attracted to it because of their keen interest in learning more about the universe. The best way to learn science is to do science. Happily, the technology available to today's amateur astronomers — including computer-controlled telescopes, CCD cameras, powerful astronomical software, and the Internet — gives them the potential to make real contributions to scientific research and to help support local educational objectives. Meanwhile, professional astronomers are losing access to small telescopes as funding is shifted to larger projects, including survey programs that will soon discover countless interesting objects needing follow-up observations. Clearly the field is ripe with opportunities for amateurs, professionals, and educators to collaborate. Amateurs will benefit from mentoring by expert professionals, pros will benefit from observations and data processing by increasingly knowledgeable amateurs, and educators will benefit from a larger pool of skilled talent to help them carry out astronomy-education initiatives. We will look at some successful pro-am collaborations that have already borne fruit and examine areas where the need and/or potential for new partnerships is especially large. In keeping with the theme of this special session, we will focus on how pro-am collaborations in astronomy can contribute to science education both inside and outside the classroom, not only for students of school age but also for adults who may not have enjoyed particularly good science education when they were younger. Because nighttime observations with sophisticated equipment are not always possible in formal educational settings, we will also mention other types of pro-am partnerships, including those involving remote observing, data mining, and/or distributed computing.

  20. The utility of Pro Forma Income Statements.

    PubMed

    Reiboldt, Max; Reiboldt, John

    2002-01-01

    Recent headlines surrounding the financial demise of the nation's seventh largest company, Enron, and its subsequent entanglements with its accounting and consulting firm, Arthur Andersen, have placed a cloud of suspicion upon many reasonable business practices that otherwise are considered standard procedure. The proforma income statement is one of those practices. An oft-used tool in financial management, pro formas play a useful role for projecting financial performance based on predictable forecasts or assumptions. Regardless of the current scrutiny, there is still a valid use for accurately prepared statements. PMID:12389329

  1. The key actors maintaining elders in functional autonomy in Bobo-Dioulasso (Burkina Faso)

    PubMed Central

    2014-01-01

    Background Globally, a significant increase in functional disability among the elderly is expected in the near future. It is therefore vital to begin considering how Sub-Saharan Africa countries can best start building or strengthening the care and support system for that target population. Study objectives are: 1) identify the key actors of the social system who maintain elders in functional autonomy at home in Bobo-Dioulasso (Burkina Faso) and 2) to describe the functional status of older people living at home. Methods We conducted a longitudinal descriptive study among the elderly aged 60 and above (351). Their functional status was evaluated using the Functional Autonomy Measurement System (SMAF). Data analysis was done using the statistical software package STATA (SE11). Results In Bobo-Dioulasso, 68% of seniors have good functional capacity or a slight incapacity and 32% have moderate to severe incapacities. Older people die before (3%) or during (14%) moderate to severe disabilities. This would mean that the quality of medical and/or social care is not good for maintaining functional autonomy of older people with moderate to severe disabilities. Two main groups of people contribute to maintain elders in functional autonomy: the elderly themselves and their family. Community, private or public structures for maintaining elders in functional autonomy are non-existent. The social system for maintaining elders in functional autonomy is incomplete and failing. In case of functional handicap at home, the elders die. But stakeholders are not conscious of this situation; they believe that this system is good for maintaining elders in functional autonomy. Conclusion It is likely that the absence of formal care and support structure likely shortens the lifespan of severely disabled older people. Stakeholders have not yet looked at this possibility. The stakeholders should seriously think about: 1) how to establish the third level of actors who can fulfill the needs to

  2. Visions of the Future - the Changing Role of Actors in Data-Intensive Science

    NASA Astrophysics Data System (ADS)

    Schäfer, L.; Klump, J. F.

    2013-12-01

    Around the world scientific disciplines are increasingly facing the challenge of a burgeoning volume of research data. This data avalanche consists of a stream of information generated from sensors and scientific instruments, digital recordings, social-science surveys or drawn from the World Wide Web. All areas of the scientific economy are affected by this rapid growth in data, from the logging of digs in Archaeology, telescope data with observations of distant galaxies in Astrophysics or data from polls and surveys in the Social Sciences. The challenge for science is not only to process the data through analysis, reduction and visualization, but also to set up infrastructures for provisioning and storing the data. The rise of new technologies and developments also poses new challenges for the actors in the area of research data infrastructures. Libraries, as one of the actors, enable access to digital media and support the publication of research data and its long-term archiving. Digital media and research data, however, introduce new aspects into the libraries' range of activities. How are we to imagine the library of the future? The library as an interface to the computer centers? Will library and computer center fuse into a new service unit? What role will scientific publishers play in future? Currently the traditional form of publication still carry greater weight - articles for conferences and journals. But will this still be the case in future? New forms of publication are already making their presence felt. The tasks of the computer centers may also change. Yesterday their remit was provisioning of rapid hardware, whereas now everything revolves around the topic of data and services. Finally, how about the researchers themselves? Not such a long time ago, Geoscience was not necessarily seen as linked to Computer Science. Nowadays, modern Geoscience relies heavily on IT and its techniques. Thus, in how far will the profile of the modern geoscientist change

  3. ProSAT+: visualizing sequence annotations on 3D structure.

    PubMed

    Stank, Antonia; Richter, Stefan; Wade, Rebecca C

    2016-08-01

    PRO: tein S: tructure A: nnotation T: ool-plus (ProSAT(+)) is a new web server for mapping protein sequence annotations onto a protein structure and visualizing them simultaneously with the structure. ProSAT(+) incorporates many of the features of the preceding ProSAT and ProSAT2 tools but also provides new options for the visualization and sharing of protein annotations. Data are extracted from the UniProt KnowledgeBase, the RCSB PDB and the PDBe SIFTS resource, and visualization is performed using JSmol. User-defined sequence annotations can be added directly to the URL, thus enabling visualization and easy data sharing. ProSAT(+) is available at http://prosat.h-its.org. PMID:27284084

  4. [The prevention of voice disorders in the actor: protocol and follow-up nine months of professional theater].

    PubMed

    Ormezzano, Y; Delale, A; Lamy-Simonian, A

    2011-01-01

    In July 2009, at the beginning of this work, 26 theses addressing professional principles of voice were listed in the database of SUDOC (Système Universitaire de Documentation): 9 related to voices of teachers (about 900,000* professionals in France), 14 theses relating to singers (7500** professionals), and only 3 about the voice of actors (20 000*** professional actors in France in 2006). The latter pertaining to concerning rookie actors (sensibilisation vocale auprès du comédien débutant Bichet, Linda, Bordeaux II, 2006), the mechanical larynx (étude des mécanismes laryngés dans la voix projetée: cas particulier des comédiennes Guerin, Mélanie, Paris VI, 2009), vocal fatigue (Fatigue vocale après une tâche d'utilisation prolongée de la voix chez le comédien Canaan Baggioni, Brigitte, Aix-Marseille II, 2009). Professional actors are plentiful; their training in vocal technique is very heterogeneous, or non-existent: it is not a prerequisite to have a degree to work as an actor! This lack of vocal technique is associated with risk factors specific to the acting profession: numerous travels in air-conditioned vehicles, unsuitable workplaces; dusty or poorly heated, irregular working patterns, excessive demands from directors... All this makes the actors highly susceptible to voice disorders. The protocol for the prevention of voice disorders presented here is holistic and ecological. This work also examines the effectiveness of such a preventive protocol aimed at theatre comedians. PMID:21977701

  5. Actor-Network Theory and its role in understanding the implementation of information technology developments in healthcare

    PubMed Central

    2010-01-01

    Background Actor-Network Theory (ANT) is an increasingly influential, but still deeply contested, approach to understand humans and their interactions with inanimate objects. We argue that health services research, and in particular evaluations of complex IT systems in health service organisations, may benefit from being informed by Actor-Network Theory perspectives. Discussion Despite some limitations, an Actor-Network Theory-based approach is conceptually useful in helping to appreciate the complexity of reality (including the complexity of organisations) and the active role of technology in this context. This can prove helpful in understanding how social effects are generated as a result of associations between different actors in a network. Of central importance in this respect is that Actor-Network Theory provides a lens through which to view the role of technology in shaping social processes. Attention to this shaping role can contribute to a more holistic appreciation of the complexity of technology introduction in healthcare settings. It can also prove practically useful in providing a theoretically informed approach to sampling (by drawing on informants that are related to the technology in question) and analysis (by providing a conceptual tool and vocabulary that can form the basis for interpretations). We draw on existing empirical work in this area and our ongoing work investigating the integration of electronic health record systems introduced as part of England's National Programme for Information Technology to illustrate salient points. Summary Actor-Network Theory needs to be used pragmatically with an appreciation of its shortcomings. Our experiences suggest it can be helpful in investigating technology implementations in healthcare settings. PMID:21040575

  6. Performance evaluation of a simulated data-flow computer with low-resolution actors

    NASA Technical Reports Server (NTRS)

    Gaudiot, J. L.; Ercegovac, M. D.

    1985-01-01

    Basic problems related to the exploitation of parallelism in a program include sequencing of the instructions and communication of the data. It is pointed out that the data-flow approach offers an elegant solution to the sequencing problem, since all data dependencies are automatically handled and only instructions with ready input sets are activated. It is shown that a change in the level of subcomputations (actors) affects communications costs. The concept of variable resolution is discussed, and the testbed environment is examined. Attention is given to the architecture of the processing elements, the communication network, and the simulators. A description of the analytical model is also provided. Simulation and results are discussed, taking into account test programs and allocation, the variation of the number of processing elements, the variation of the resolution in directed acyclic graphs, performance in processing loops, and array handling.

  7. Clients' and therapists' real relationship and session quality in brief therapy: an actor partner interdependence analysis.

    PubMed

    Markin, Rayna D; Kivlighan, Dennis M; Gelso, Charles J; Hummel, Ann M; Spiegel, Eric B

    2014-09-01

    This study used the Actor Partner Interdependence Model (APIM; Kenny & Cook, 1999) to examine the associations of client- and therapist-rated real relationship (RR) and session quality over time. Eighty-seven clients and their therapists (n = 25) completed RR and session quality measures after every session of brief therapy. Therapists' current session quality ratings were significantly related to all of the following: session number (b = .04), their session quality rating of the previous session (b = .24), their RR in the previous session (b = 1.091), their client's RR in the previous session (b = .17), and interactions between their own and their clients' RR and session number (b = -.16 and β = -.04, respectively). Clients' ratings of current session quality were significantly related to only their own RR in the previous session (b = .47). Implications for future research and practice are discussed. PMID:24773091

  8. Explicit recognition of emotional facial expressions is shaped by expertise: evidence from professional actors

    PubMed Central

    Conson, Massimiliano; Ponari, Marta; Monteforte, Eva; Ricciato, Giusy; Sarà, Marco; Grossi, Dario; Trojano, Luigi

    2013-01-01

    Can reading others' emotional states be shaped by expertise? We assessed processing of emotional facial expressions in professional actors trained either to voluntary activate mimicry to reproduce character's emotions (as foreseen by the “Mimic Method”), or to infer others' inner states from reading the emotional context (as foreseen by “Stanislavski Method”). In explicit recognition of facial expressions (Experiment 1), the two experimental groups differed from each other and from a control group with no acting experience: the Mimic group was more accurate, whereas the Stanislavski group was slower. Neither acting experience, instead, influenced implicit processing of emotional faces (Experiment 2). We argue that expertise can selectively influence explicit recognition of others' facial expressions, depending on the kind of “emotional expertise”. PMID:23825467

  9. Testing crossover effects in an actor-partner interdependence model among Chinese dual-earner couples.

    PubMed

    Liu, Huimin; Cheung, Fanny M

    2015-03-01

    The purpose of the present study is to examine the crossover effects from one partner's work-family interface (work-family conflict [WFC] and work-family enrichment [WFE]) to the other partner's four outcomes (psychological strain, life satisfaction, marital satisfaction and job satisfaction) in a sample of Chinese dual-earner couples. Married couples (N = 361) completed a battery of questionnaires, including the work-family interface scale, the psychological strain scale, the life, marital, as well as job satisfaction scale. Results from the actor-partner interdependence model (APIM) analyses showed that wives' WFE was negatively associated with husbands' psychological strain, and positively associated with husbands' life, marital and job satisfaction. Furthermore, husbands' WFC was negatively related to wives' marital satisfaction, whereas husbands' WFE was positively related to wives' marital satisfaction. Theoretical and practical implications were discussed, and future research directions were provided. PMID:25721880

  10. Industry Actors, Think Tanks, and Alcohol Policy in the United Kingdom

    PubMed Central

    McCambridge, Jim

    2014-01-01

    Corporate actors seek to influence alcohol policies through various means, including attempts to shape the evidential content of policy debates. In this case study, we examined how SABMiller engaged the think tank Demos to produce reports on binge drinking, which were heavily promoted among policymakers at crucial stages in the development of the UK government’s 2012 alcohol strategy. One key report coincided with other SABMiller-funded publications, advocating measures to enhance parenting as an alternative to minimum unit pricing. In this instance, the perceived independence of an influential think tank was used to promote industry interests in tactics similar to those of transnational tobacco corporations. This approach is in keeping with other alcohol industry efforts to marginalize the peer-reviewed literature. PMID:24922137

  11. Ethics in actor networks, or: what Latour could learn from Darwin and Dewey.

    PubMed

    Waelbers, Katinka; Dorstewitz, Philipp

    2014-03-01

    In contemporary Science, Technology and Society (STS) studies, Bruno Latour's Actor Network Theory (ANT) is often used to study how social change arises from interaction between people and technologies. Though Latour's approach is rich in the sense of enabling scholars to appreciate the complexity of many relevant technological, environmental, and social factors in their studies, the approach is poor from an ethical point of view: the doings of things and people are couched in one and the same behaviorist (third person) vocabulary without giving due recognition to the ethical relevance of human intelligence, sympathy and reflection in making responsible choices. This article argues that two other naturalist projects, the non-teleological virtue ethics of Charles Darwin and the pragmatist instrumentalism of John Dewey can enrich ANT-based STS studies, both, in a descriptive and in a normative sense. PMID:23371512

  12. Ensuring Mobility-Supporting Environments for an Aging Population: Critical Actors and Collaborations

    PubMed Central

    Kochtitzky, Chris S.; Freeland, Amy L.; Yen, Irene H.

    2011-01-01

    Successful aging takes on an array of attributes, including optimal health and community participation. Research indicates that (1) persons with disabilities, including age-related disabilities, report frequent barriers to community participation, including unsuitable building design (43%), transportation (32%), and sidewalks/curbs (31%), and (2) many seniors report an inability to cross roads safely near their homes. This paper attempts to define mobility-related elements that contribute to optimal health and quality of life, within the context of successful aging. It then examines the impacts of community design on individual mobility, delving into which traditional and nontraditional actors—including architects, urban planners, transportation engineers, occupational therapists, and housing authorities—play critical roles in ensuring that community environments serve as facilitators (rather than barriers) to mobility. As America ages, mobility challenges for seniors will only increase unless both traditional aging specialists and many nontraditional actors make a concerted effort to address the challenges. PMID:21766029

  13. A spiking neural network model of an actor-critic learning agent.

    PubMed

    Potjans, Wiebke; Morrison, Abigail; Diesmann, Markus

    2009-02-01

    The ability to adapt behavior to maximize reward as a result of interactions with the environment is crucial for the survival of any higher organism. In the framework of reinforcement learning, temporal-difference learning algorithms provide an effective strategy for such goal-directed adaptation, but it is unclear to what extent these algorithms are compatible with neural computation. In this article, we present a spiking neural network model that implements actor-critic temporal-difference learning by combining local plasticity rules with a global reward signal. The network is capable of solving a nontrivial gridworld task with sparse rewards. We derive a quantitative mapping of plasticity parameters and synaptic weights to the corresponding variables in the standard algorithmic formulation and demonstrate that the network learns with a similar speed to its discrete time counterpart and attains the same equilibrium performance. PMID:19196231

  14. Online human training of a myoelectric prosthesis controller via actor-critic reinforcement learning.

    PubMed

    Pilarski, Patrick M; Dawson, Michael R; Degris, Thomas; Fahimi, Farbod; Carey, Jason P; Sutton, Richard S

    2011-01-01

    As a contribution toward the goal of adaptable, intelligent artificial limbs, this work introduces a continuous actor-critic reinforcement learning method for optimizing the control of multi-function myoelectric devices. Using a simulated upper-arm robotic prosthesis, we demonstrate how it is possible to derive successful limb controllers from myoelectric data using only a sparse human-delivered training signal, without requiring detailed knowledge about the task domain. This reinforcement-based machine learning framework is well suited for use by both patients and clinical staff, and may be easily adapted to different application domains and the needs of individual amputees. To our knowledge, this is the first my-oelectric control approach that facilitates the online learning of new amputee-specific motions based only on a one-dimensional (scalar) feedback signal provided by the user of the prosthesis. PMID:22275543

  15. Impedance learning for robotic contact tasks using natural actor-critic algorithm.

    PubMed

    Kim, Byungchan; Park, Jooyoung; Park, Shinsuk; Kang, Sungchul

    2010-04-01

    Compared with their robotic counterparts, humans excel at various tasks by using their ability to adaptively modulate arm impedance parameters. This ability allows us to successfully perform contact tasks even in uncertain environments. This paper considers a learning strategy of motor skill for robotic contact tasks based on a human motor control theory and machine learning schemes. Our robot learning method employs impedance control based on the equilibrium point control theory and reinforcement learning to determine the impedance parameters for contact tasks. A recursive least-square filter-based episodic natural actor-critic algorithm is used to find the optimal impedance parameters. The effectiveness of the proposed method was tested through dynamic simulations of various contact tasks. The simulation results demonstrated that the proposed method optimizes the performance of the contact tasks in uncertain conditions of the environment. PMID:19696001

  16. Multirate parallel distributed compensation of a cluster in wireless sensor and actor networks

    NASA Astrophysics Data System (ADS)

    Yang, Chun-xi; Huang, Ling-yun; Zhang, Hao; Hua, Wang

    2016-01-01

    The stabilisation problem for one of the clusters with bounded multiple random time delays and packet dropouts in wireless sensor and actor networks is investigated in this paper. A new multirate switching model is constructed to describe the feature of this single input multiple output linear system. According to the difficulty of controller design under multi-constraints in multirate switching model, this model can be converted to a Takagi-Sugeno fuzzy model. By designing a multirate parallel distributed compensation, a sufficient condition is established to ensure this closed-loop fuzzy control system to be globally exponentially stable. The solution of the multirate parallel distributed compensation gains can be obtained by solving an auxiliary convex optimisation problem. Finally, two numerical examples are given to show, compared with solving switching controller, multirate parallel distributed compensation can be obtained easily. Furthermore, it has stronger robust stability than arbitrary switching controller and single-rate parallel distributed compensation under the same conditions.

  17. Free-viewpoint video of human actors using multiple handheld Kinects.

    PubMed

    Ye, Genzhi; Liu, Yebin; Deng, Yue; Hasler, Nils; Ji, Xiangyang; Dai, Qionghai; Theobalt, Christian

    2013-10-01

    We present an algorithm for creating free-viewpoint video of interacting humans using three handheld Kinect cameras. Our method reconstructs deforming surface geometry and temporal varying texture of humans through estimation of human poses and camera poses for every time step of the RGBZ video. Skeletal configurations and camera poses are found by solving a joint energy minimization problem, which optimizes the alignment of RGBZ data from all cameras, as well as the alignment of human shape templates to the Kinect data. The energy function is based on a combination of geometric correspondence finding, implicit scene segmentation, and correspondence finding using image features. Finally, texture recovery is achieved through jointly optimization on spatio-temporal RGB data using matrix completion. As opposed to previous methods, our algorithm succeeds on free-viewpoint video of human actors under general uncontrolled indoor scenes with potentially dynamic background, and it succeeds even if the cameras are moving. PMID:23893757

  18. THEORIZING HYBRIDITY: INSTITUTIONAL LOGICS, COMPLEX ORGANIZATIONS, AND ACTOR IDENTITIES: THE CASE OF NONPROFITS

    PubMed Central

    SKELCHER, CHRIS; SMITH, STEVEN RATHGEB

    2015-01-01

    We propose a novel approach to theorizing hybridity in public and nonprofit organizations. The concept of hybridity is widely used to describe organizational responses to changes in governance, but the literature seldom explains how hybrids arise or what forms they take. Transaction cost and organizational design literatures offer some solutions, but lack a theory of agency. We use the institutional logics approach to theorize hybrids as entities that face a plurality of normative frames. Logics provide symbolic and material elements that structure organizational legitimacy and actor identities. Contradictions between institutional logics offer space for them to be elaborated and creatively reconstructed by situated agents. We propose five types of organizational hybridity – segmented, segregated, assimilated, blended, and blocked. Each type is theoretically derived from empirically observed variations in organizational responses to institutional plurality. We develop propositions to show how our approach to hybridity adds value to academic and policy-maker audiences. PMID:26640298

  19. Rejection sensitivity and depressive symptoms: Longitudinal actor-partner effects in adolescent romantic relationships.

    PubMed

    Norona, Jerika C; Roberson, Patricia N E; Welsh, Deborah P

    2016-08-01

    The present study utilizes the actor-partner interdependence model to examine the longitudinal relationship between rejection sensitivity and one's own and one's partner's depressive symptoms. The sample included adolescent romantic couples from the U.S. (N = 198 adolescents; 50% girls; 90.2% Caucasian) whose rejection sensitivity at Time 1 and depressive symptoms approximately one year later (Time 2) were assessed. Additionally, aggressive behaviors and maintenance behaviors that commonly associated with rejection sensitivity (e.g., self-silencing) are explored as mediators. Results indicate that boyfriends' rejection sensitivity at Time 1 predicted girlfriends' depressive symptoms at Time 2. Additionally, girls' rejection sensitivity predicted their own and their boyfriends' self-silencing. Developmental and clinical implications are discussed. PMID:27254083

  20. Integrating Water, Actors, and Structure to Study Socio-Hydro-Ecological Systems

    NASA Astrophysics Data System (ADS)

    Hale, R. L.; Armstrong, A.; Baker, M. A.; Bedingfield, S.; Betts, D.; Buahin, C. A.; Buchert, M.; Crowl, T.; Dupont, R.; Endter-Wada, J.; Flint, C.; Grant, J.; Hinners, S.; Horns, D.; Horsburgh, J. S.; Jackson-Smith, D.; Jones, A. S.; Licon, C.; Null, S. E.; Odame, A.; Pataki, D. E.; Rosenberg, D. E.; Runburg, M.; Stoker, P.; Strong, C.

    2014-12-01

    Urbanization, climate uncertainty, and ecosystem change represent major challenges for managing water resources. Water systems and the forces acting upon them are complex, and there is a need to understand and generically represent the most important system components and linkages. We developed a framework to facilitate understanding of water systems including potential vulnerabilities and opportunities for sustainability. Our goal was to produce an interdisciplinary framework for water resources research to address water issues across scales (e.g., city to region) and domains (e.g., water supply and quality, urban and transitioning landscapes). An interdisciplinary project (iUTAH - innovative Urban Transitions and Aridregion Hydro-sustainability) with a large (N=~100), diverse team having expertise spanning the hydrologic, biological, ecological, engineering, social, planning, and policy sciences motivated the development of this framework. The framework was developed through review of the literature, meetings with individual researchers, and workshops with participants. The Structure-Water-Actor Framework (SWAF) includes three main components: water (quality and quantity), structure (natural, built, and social), and actors (individual and organizational). Key linkages include: 1) ecological and hydrological processes, 2) ecosystem and geomorphic change, 3) planning, design, and policy, 4) perceptions, information, and experience, 5) resource access, and 6) operational water use and management. Our expansive view of structure includes natural, built, and social components, allowing us to examine a broad set of tools and levers for water managers and decision-makers to affect system sustainability and understand system outcomes. We validate the SWAF and illustrate its flexibility to generate insights for three research and management problems: green stormwater infrastructure in an arid environment, regional water supply and demand, and urban river restoration

  1. iSAW: Integrating Structure, Actors, and Water to study socio-hydro-ecological systems

    NASA Astrophysics Data System (ADS)

    Hale, Rebecca L.; Armstrong, Andrea; Baker, Michelle A.; Bedingfield, Sean; Betts, David; Buahin, Caleb; Buchert, Martin; Crowl, Todd; Dupont, R. Ryan; Ehleringer, James R.; Endter-Wada, Joanna; Flint, Courtney; Grant, Jacqualine; Hinners, Sarah; Horsburgh, Jeffery S.; Jackson-Smith, Douglas; Jones, Amber S.; Licon, Carlos; Null, Sarah E.; Odame, Augustina; Pataki, Diane E.; Rosenberg, David; Runburg, Madlyn; Stoker, Philip; Strong, Courtenay

    2015-03-01

    Urbanization, climate, and ecosystem change represent major challenges for managing water resources. Although water systems are complex, a need exists for a generalized representation of these systems to identify important components and linkages to guide scientific inquiry and aid water management. We developed an integrated Structure-Actor-Water framework (iSAW) to facilitate the understanding of and transitions to sustainable water systems. Our goal was to produce an interdisciplinary framework for water resources research that could address management challenges across scales (e.g., plot to region) and domains (e.g., water supply and quality, transitioning, and urban landscapes). The framework was designed to be generalizable across all human-environment systems, yet with sufficient detail and flexibility to be customized to specific cases. iSAW includes three major components: structure (natural, built, and social), actors (individual and organizational), and water (quality and quantity). Key linkages among these components include: (1) ecological/hydrologic processes, (2) ecosystem/geomorphic feedbacks, (3) planning, design, and policy, (4) perceptions, information, and experience, (5) resource access and risk, and (6) operational water use and management. We illustrate the flexibility and utility of the iSAW framework by applying it to two research and management problems: understanding urban water supply and demand in a changing climate and expanding use of green storm water infrastructure in a semi-arid environment. The applications demonstrate that a generalized conceptual model can identify important components and linkages in complex and diverse water systems and facilitate communication about those systems among researchers from diverse disciplines.

  2. Reinforcement learning using a continuous time actor-critic framework with spiking neurons.

    PubMed

    Frémaux, Nicolas; Sprekeler, Henning; Gerstner, Wulfram

    2013-04-01

    Animals repeat rewarded behaviors, but the physiological basis of reward-based learning has only been partially elucidated. On one hand, experimental evidence shows that the neuromodulator dopamine carries information about rewards and affects synaptic plasticity. On the other hand, the theory of reinforcement learning provides a framework for reward-based learning. Recent models of reward-modulated spike-timing-dependent plasticity have made first steps towards bridging the gap between the two approaches, but faced two problems. First, reinforcement learning is typically formulated in a discrete framework, ill-adapted to the description of natural situations. Second, biologically plausible models of reward-modulated spike-timing-dependent plasticity require precise calculation of the reward prediction error, yet it remains to be shown how this can be computed by neurons. Here we propose a solution to these problems by extending the continuous temporal difference (TD) learning of Doya (2000) to the case of spiking neurons in an actor-critic network operating in continuous time, and with continuous state and action representations. In our model, the critic learns to predict expected future rewards in real time. Its activity, together with actual rewards, conditions the delivery of a neuromodulatory TD signal to itself and to the actor, which is responsible for action choice. In simulations, we show that such an architecture can solve a Morris water-maze-like navigation task, in a number of trials consistent with reported animal performance. We also use our model to solve the acrobot and the cartpole problems, two complex motor control tasks. Our model provides a plausible way of computing reward prediction error in the brain. Moreover, the analytically derived learning rule is consistent with experimental evidence for dopamine-modulated spike-timing-dependent plasticity. PMID:23592970

  3. Reinforcement Learning Using a Continuous Time Actor-Critic Framework with Spiking Neurons

    PubMed Central

    Frémaux, Nicolas; Sprekeler, Henning; Gerstner, Wulfram

    2013-01-01

    Animals repeat rewarded behaviors, but the physiological basis of reward-based learning has only been partially elucidated. On one hand, experimental evidence shows that the neuromodulator dopamine carries information about rewards and affects synaptic plasticity. On the other hand, the theory of reinforcement learning provides a framework for reward-based learning. Recent models of reward-modulated spike-timing-dependent plasticity have made first steps towards bridging the gap between the two approaches, but faced two problems. First, reinforcement learning is typically formulated in a discrete framework, ill-adapted to the description of natural situations. Second, biologically plausible models of reward-modulated spike-timing-dependent plasticity require precise calculation of the reward prediction error, yet it remains to be shown how this can be computed by neurons. Here we propose a solution to these problems by extending the continuous temporal difference (TD) learning of Doya (2000) to the case of spiking neurons in an actor-critic network operating in continuous time, and with continuous state and action representations. In our model, the critic learns to predict expected future rewards in real time. Its activity, together with actual rewards, conditions the delivery of a neuromodulatory TD signal to itself and to the actor, which is responsible for action choice. In simulations, we show that such an architecture can solve a Morris water-maze-like navigation task, in a number of trials consistent with reported animal performance. We also use our model to solve the acrobot and the cartpole problems, two complex motor control tasks. Our model provides a plausible way of computing reward prediction error in the brain. Moreover, the analytically derived learning rule is consistent with experimental evidence for dopamine-modulated spike-timing-dependent plasticity. PMID:23592970

  4. Vocal fold self-disruption after phonotrauma on a lead actor: a case presentation.

    PubMed

    Behlau, Mara; Oliveira, Gisele; Pontes, Paulo

    2009-11-01

    It is well known that phonotraumatic events may produce laryngeal inflammation, vocal fold hemorrhage and different types of mass lesions. This study describes a vocal fold self-disruption that occurred on stage to a lead actor in the role of Richard III. The study design is as case presentation. A 43-year-old actor presented with a sudden voice loss that first occurred on stage after a series of presentations. He also had a cold-like condition that had not been treated. His past medical history included an average of ten cigarettes per day for ten years and a 10-year history of gastritis and stomach ulcer. Perceptual, acoustic, and laryngeal analyses were performed following pharmacological and voice therapy. Perceptual and acoustic analyses showed mild deviations whereas laryngeal visual examination revealed a complete right vocal fold detachment from the anterior commissure to the vocal process, with generalized hyperemia. A mild diffuse Reinke's edema was observed on the left vocal fold. Mild discomfort was present only during the first day of the acute period. Modified vocal rest was recommended and a series of vocal exercises were administered. The patient performed again 4 days later, after following a series of behavioral modification techniques that included casting guidelines during the subsequent 15 days. Healing was exceptional and his voice returned to normal. This unique case with an exceptional recovery emphasizes the etiological aspects of scar formation after phonotrauma. Positive contributing factors may include a good vocal technique and adequate training as well as the protective upregulated genes present in Reinke's edema. PMID:18538985

  5. Pro-Anorexia and Anti-Pro-Anorexia Videos on YouTube: Sentiment Analysis of User Responses

    PubMed Central

    Garcia, David; Sirola, Anu; Näsi, Matti; Kaakinen, Markus; Keipi, Teo; Räsänen, Pekka

    2015-01-01

    Background Pro-anorexia communities exist online and encourage harmful weight loss and weight control practices, often through emotional content that enforces social ties within these communities. User-generated responses to videos that directly oppose pro-anorexia communities have not yet been researched in depth. Objective The aim was to study emotional reactions to pro-anorexia and anti-pro-anorexia online content on YouTube using sentiment analysis. Methods Using the 50 most popular YouTube pro-anorexia and anti-pro-anorexia user channels as a starting point, we gathered data on users, their videos, and their commentators. A total of 395 anorexia videos and 12,161 comments were analyzed using positive and negative sentiments and ratings submitted by the viewers of the videos. The emotional information was automatically extracted with an automatic sentiment detection tool whose reliability was tested with human coders. Ordinary least squares regression models were used to estimate the strength of sentiments. The models controlled for the number of video views and comments, number of months the video had been on YouTube, duration of the video, uploader’s activity as a video commentator, and uploader’s physical location by country. Results The 395 videos had more than 6 million views and comments by almost 8000 users. Anti-pro-anorexia video comments expressed more positive sentiments on a scale of 1 to 5 (adjusted prediction [AP] 2.15, 95% CI 2.11-2.19) than did those of pro-anorexia videos (AP 2.02, 95% CI 1.98-2.06). Anti-pro-anorexia videos also received more likes (AP 181.02, 95% CI 155.19-206.85) than pro-anorexia videos (AP 31.22, 95% CI 31.22-37.81). Negative sentiments and video dislikes were equally distributed in responses to both pro-anorexia and anti-pro-anorexia videos. Conclusions Despite pro-anorexia content being widespread on YouTube, videos promoting help for anorexia and opposing the pro-anorexia community were more popular, gaining more

  6. Actor-Network Theory as a sociotechnical lens to explore the relationship of nurses and technology in practice: methodological considerations for nursing research.

    PubMed

    Booth, Richard G; Andrusyszyn, Mary-Anne; Iwasiw, Carroll; Donelle, Lorie; Compeau, Deborah

    2016-06-01

    Actor-Network Theory is a research lens that has gained popularity in the nursing and health sciences domains. The perspective allows a researcher to describe the interaction of actors (both human and non-human) within networked sociomaterial contexts, including complex practice environments where nurses and health technology operate. This study will describe Actor-Network Theory and provide methodological considerations for researchers who are interested in using this sociotechnical lens within nursing and informatics-related research. Considerations related to technology conceptualization, levels of analysis, and sampling procedures in Actor-Network Theory based research are addressed. Finally, implications for future nursing research within complex environments are highlighted. PMID:26531190

  7. Pro-sociality and strategic reasoning in economic decisions

    PubMed Central

    Arruñada, Benito; Casari, Marco; Pancotto, Francesca

    2015-01-01

    We study the relationship between pro-social preferences and strategic reasoning. These aspects are typically studied separately but little is known about their joint distribution. In an experiment, for each participant we elicit individual concerns toward pro-sociality—inequality aversion and efficiency—as well as the number of steps of reasoning through a guessing game. We report that self-regarding and pro-social participants exhibit similar levels of strategic reasoning, which supports the view that pro-sociality and strategic reasoning can be studied independently. PMID:26074799

  8. InterPro, progress and status in 2005.

    PubMed

    Mulder, Nicola J; Apweiler, Rolf; Attwood, Teresa K; Bairoch, Amos; Bateman, Alex; Binns, David; Bradley, Paul; Bork, Peer; Bucher, Phillip; Cerutti, Lorenzo; Copley, Richard; Courcelle, Emmanuel; Das, Ujjwal; Durbin, Richard; Fleischmann, Wolfgang; Gough, Julian; Haft, Daniel; Harte, Nicola; Hulo, Nicolas; Kahn, Daniel; Kanapin, Alexander; Krestyaninova, Maria; Lonsdale, David; Lopez, Rodrigo; Letunic, Ivica; Madera, Martin; Maslen, John; McDowall, Jennifer; Mitchell, Alex; Nikolskaya, Anastasia N; Orchard, Sandra; Pagni, Marco; Ponting, Chris P; Quevillon, Emmanuel; Selengut, Jeremy; Sigrist, Christian J A; Silventoinen, Ville; Studholme, David J; Vaughan, Robert; Wu, Cathy H

    2005-01-01

    InterPro, an integrated documentation resource of protein families, domains and functional sites, was created to integrate the major protein signature databases. Currently, it includes PROSITE, Pfam, PRINTS, ProDom, SMART, TIGRFAMs, PIRSF and SUPERFAMILY. Signatures are manually integrated into InterPro entries that are curated to provide biological and functional information. Annotation is provided in an abstract, Gene Ontology mapping and links to specialized databases. New features of InterPro include extended protein match views, taxonomic range information and protein 3D structure data. One of the new match views is the InterPro Domain Architecture view, which shows the domain composition of protein matches. Two new entry types were introduced to better describe InterPro entries: these are active site and binding site. PIRSF and the structure-based SUPERFAMILY are the latest member databases to join InterPro, and CATH and PANTHER are soon to be integrated. InterPro release 8.0 contains 11 007 entries, representing 2573 domains, 8166 families, 201 repeats, 26 active sites, 21 binding sites and 20 post-translational modification sites. InterPro covers over 78% of all proteins in the Swiss-Prot and TrEMBL components of UniProt. The database is available for text- and sequence-based searches via a webserver (http://www.ebi.ac.uk/interpro), and for download by anonymous FTP (ftp://ftp.ebi.ac.uk/pub/databases/interpro). PMID:15608177

  9. InterPro, progress and status in 2005

    PubMed Central

    Mulder, Nicola J.; Apweiler, Rolf; Attwood, Teresa K.; Bairoch, Amos; Bateman, Alex; Binns, David; Bradley, Paul; Bork, Peer; Bucher, Phillip; Cerutti, Lorenzo; Copley, Richard; Courcelle, Emmanuel; Das, Ujjwal; Durbin, Richard; Fleischmann, Wolfgang; Gough, Julian; Haft, Daniel; Harte, Nicola; Hulo, Nicolas; Kahn, Daniel; Kanapin, Alexander; Krestyaninova, Maria; Lonsdale, David; Lopez, Rodrigo; Letunic, Ivica; Madera, Martin; Maslen, John; McDowall, Jennifer; Mitchell, Alex; Nikolskaya, Anastasia N.; Orchard, Sandra; Pagni, Marco; Ponting, Chris P.; Quevillon, Emmanuel; Selengut, Jeremy; Sigrist, Christian J. A.; Silventoinen, Ville; Studholme, David J.; Vaughan, Robert; Wu, Cathy H.

    2005-01-01

    InterPro, an integrated documentation resource of protein families, domains and functional sites, was created to integrate the major protein signature databases. Currently, it includes PROSITE, Pfam, PRINTS, ProDom, SMART, TIGRFAMs, PIRSF and SUPERFAMILY. Signatures are manually integrated into InterPro entries that are curated to provide biological and functional information. Annotation is provided in an abstract, Gene Ontology mapping and links to specialized databases. New features of InterPro include extended protein match views, taxonomic range information and protein 3D structure data. One of the new match views is the InterPro Domain Architecture view, which shows the domain composition of protein matches. Two new entry types were introduced to better describe InterPro entries: these are active site and binding site. PIRSF and the structure-based SUPERFAMILY are the latest member databases to join InterPro, and CATH and PANTHER are soon to be integrated. InterPro release 8.0 contains 11 007 entries, representing 2573 domains, 8166 families, 201 repeats, 26 active sites, 21 binding sites and 20 post-translational modification sites. InterPro covers over 78% of all proteins in the Swiss-Prot and TrEMBL components of UniProt. The database is available for text- and sequence-based searches via a webserver (http://www.ebi.ac.uk/interpro), and for download by anonymous FTP (ftp://ftp.ebi.ac.uk/pub/databases/interpro). PMID:15608177

  10. Pro-sociality and strategic reasoning in economic decisions.

    PubMed

    Arruñada, Benito; Casari, Marco; Pancotto, Francesca

    2015-01-01

    We study the relationship between pro-social preferences and strategic reasoning. These aspects are typically studied separately but little is known about their joint distribution. In an experiment, for each participant we elicit individual concerns toward pro-sociality-inequality aversion and efficiency-as well as the number of steps of reasoning through a guessing game. We report that self-regarding and pro-social participants exhibit similar levels of strategic reasoning, which supports the view that pro-sociality and strategic reasoning can be studied independently. PMID:26074799