Sample records for additional www sites

  1. NASA Parts Selection List (NPSL) WWW Site http://nepp.nasa.gov/npsl

    NASA Technical Reports Server (NTRS)

    Brusse, Jay

    2000-01-01

    The NASA Parts Selection List (NPSL) is an on-line resource for electronic parts selection tailored for use by spaceflight projects. The NPSL provides a list of commonly used electronic parts that have a history of satisfactory use in spaceflight applications. The objective of this www site is to provide NASA projects, contractors, university experimenters, et al with an easy to use resource that provides a baseline of electronic parts from which designers are encouraged to select. The NPSL is an ongoing resource produced by Code 562 in support of the NASA HQ funded NASA Electronic Parts and Packaging (NEPP) Program. The NPSL is produced as an electronic format deliverable made available via the referenced www site administered by Code 562. The NPSL does not provide information pertaining to patented or proprietary information. All of the information contained in the NPSL is available through various other public domain resources such as US Military procurement specifications for electronic parts, NASA GSFC's Preferred Parts List (PPL-21), and NASA's Standard Parts List (MIL-STD975).

  2. Active and Passive Supplier Assessment Program (ASAP & PSAP) WWW Sites http://nepp.nasa.gov/imd/asap http://nepp.nasa.gov/imd/psap

    NASA Technical Reports Server (NTRS)

    Brusse, Jay

    2000-01-01

    The Active and Passive Supplier Assessment Programs (ASAP and PSAP) WWW Sites provide general information to the electronic parts community regarding the availability of electronic parts. They also provide information to NASA regarding modifications to commonly used procurement specifications and test methods. The ASAP and PSAP www sites are ongoing resources produced by Code 562 in support of the NASA HQ funded NASA Electronic Parts and Packaging (NEPP) Program. These WWW sites do not provide information pertaining to patented or proprietary information. All of the information contained in these www sites is available through various other public domain resources such as US Military Qualified Producers Listings (QPLs) and Qualified Manufacturer Listings (QMLs) and industry working groups such as the Electronics Industry Alliance (EIA) and the Space Parts Working Group (SPWG).

  3. Build a WWW Homepage for Your School!

    ERIC Educational Resources Information Center

    Chrobak, Kimberly

    1995-01-01

    Discusses the use of World Wide Web (WWW) Homepage for school information. Topics include school sites; installation of a WWW browser; file tags; sites for beginner's guides to the language (HTML); two Usenet discussion groups; and a sample lesson plan including objective, procedure, and evaluation. (AEF)

  4. WWW: Neuroscience Web Sites

    ERIC Educational Resources Information Center

    Liu, Dennis

    2006-01-01

    The human brain contains an estimated 100 billion neurons, and browsing the Web, one might be led to believe that there's a Web site for every one of those cells. It's no surprise that there are lots of Web sites concerning the nervous system. After all, the human brain is toward the top of nearly everyone's list of favorite organs and of…

  5. Image Reference Database in Teleradiology: Migrating to WWW

    NASA Astrophysics Data System (ADS)

    Pasqui, Valdo

    The paper presents a multimedia Image Reference Data Base (IRDB) used in Teleradiology. The application was developed at the University of Florence in the framework of the European Community TELEMED Project. TELEMED overall goals and IRDB requirements are outlined and the resulting architecture is described. IRDB is a multisite database containing radiological images, selected because their scientific interest, and their related information. The architecture consists of a set of IRDB Installations which are accessed from Viewing Stations (VS) located at different medical sites. The interaction between VS and IRDB Installations follows the client-server paradigm and uses an OSI level-7 protocol, named Telemed Communication Language. After reviewing Florence prototype implementation and experimentation, IRDB migration to World Wide Web (WWW) is discussed. A possible scenery to implement IRDB on the basis of WWW model is depicted in order to exploit WWW servers and browsers capabilities. Finally, the advantages of this conversion are outlined.

  6. WWW.cell Biology Education: Evolution Web Sites

    ERIC Educational Resources Information Center

    Liu, Dennis

    2005-01-01

    The debate over teaching evolution has once again reached a fever pitch in the United States. Earnest nineteenth-century clashes between scientific and religious worldviews have given way to the politically charged arguments of creation science and now intelligent design. The Web site of the National Center for Science Education (NCSE;…

  7. Site Preference of Ternary Alloying Additions to AuTi

    NASA Technical Reports Server (NTRS)

    Bozzolo, Guillermo; Mosca, Hugo O.; Noebe, Ronald D.

    2006-01-01

    Atomistic modeling of the site substitution behavior of several alloying additions, namely. Na, Mg, Al, Si. Sc, V, Cr, Mn. Fe, Co, Ni, Cu, Zn, Y, Zr. Nb, Mo, Tc, Ru, Rh, Pd, Ag, Cd, Hf, Ta, W, Re, Os, Ir, and Pt in B2 TiAu is reported. The 30 elements can be grouped according to their absolute preference for a specific site, regardless of concentration, or preference for available sites in the deficient sublattice. Results of large scale simulations are also presented, distinguishing between additions that remain in solution from those that precipitate a second phase.

  8. Insights on WWW-based geoscience teaching: Climbing the first year learning cliff

    NASA Astrophysics Data System (ADS)

    Lamberson, Michelle N.; Johnson, Mark; Bevier, Mary Lou; Russell, J. Kelly

    1997-06-01

    In early 1995, The University of British Columbia Department of Geological Sciences (now Earth and Ocean Sciences) initiated a project that explored the effectiveness of the World Wide Web as a teaching and learning medium. Four decisions made at the onset of the project have guided the department's educational technology plan: (1) over 90% of funding recieved from educational technology grants was committed towards personnel; (2) materials developed are modular in design; (3) a data-base approach was taken to resource development; and (4) a strong commitment to student involvement in courseware development. The project comprised development of a web site for an existing core course: Geology 202, Introduction to Petrology. The web site is a gateway to course information, content, resources, exercises, and several searchable data-bases (images, petrologic definitions, and minerals in thin section). Material was developed on either an IBM or UNIX machine, ported to a UNIX platform, and is accessed using the Netscape browser. The resources consist primarily of HTML files or CGI scripts with associated text, images, sound, digital movies, and animations. Students access the web site from the departmental student computer facility, from home or a computer station in the petrology laboratory. Results of a survey of the Geol 202 students indicate that they found the majority of the resources useful, and the site is being expanded. The Geology 202 project had a "trickle-up" effect throughout the department: prior to this project, there was minimal use of Internet resources in lower-level geology courses. By the end of the 1996-1997 academic year, we anticipate that at least 17 Earth and Ocean Science courses will have a WWW site for one or all of the following uses: (1) presenting basic information; (2) accessing lecture images; (3) providing a jumping-off point for exploring related WWW sites; (4) conducting on-line exercises; and/or (5) providing a communications forum

  9. The CpG island searcher: a new WWW resource.

    PubMed

    Takai, Daiya; Jones, Peter A

    2003-01-01

    Clusters of CpG dinucleotides in GC rich regions of the genome called "CpG islands" frequently occur in the 5' ends of genes. Methylation of CpG islands plays a role in transcriptional silencing in higher organisms in certain situations. We have established a CpG-island-extraction algorithm, which we previously developed [Takai and Jones, 2002], on a web site which has a simple user interface to identify CpG islands from submitted sequences of up to 50kb. The web site determines the locations of CpG islands using parameters (lower limit of %GC, ObsCpG/ExpCpG, length) set by the user, to display the value of parameters on each CpG island, and provides a graphical map of CpG dinucleotide distribution and borders of CpG islands. A command-line version of the CpG islands searcher has also been developed for larger sequences. The CpG Island Searcher was applied to the latest sequence and mapping information of human chromosomes 20, 21 and 22, and a total of 2345 CpG islands were extracted and 534 (23%) of them contained first coding exons and 650 (28%) contained other exons. The CpG Island Searcher is available on the World Wide Web at http://www.cpgislands.com or http://www.uscnorris.com/cpgislands/cpg.cgi.

  10. Health information for young people where and when they most want it: a case study of www.teenagehealthfreak.org.

    PubMed

    McPherson, Ann; Macfarlane, Aidan

    2007-08-01

    The Internet is an exciting resource for providing immediately available, evidence-based, health information for young people in an age-appropriate form on a 24 hours/day, 7 days/week basis. www.teenagehealthfreak.org is a United Kingdom-based Web site designed to take advantage of this. The content of the site, which is the leading teenage health Web site on a Google search, contains both the diary of a hypochondriac 15-year-old boy and a virtual doctor's surgery. It also allows for young people to e-mail health-related questions and receive relevant answers from a health expert. Analysis of the content of these e-mails indicates the unmet health needs and concerns of young people. Future developments of the site include linking the site www.youthhealthtalk.org, a Web site that contains videotaped interviews with young people who have a variety other health concerns.

  11. Environmental projects, volume 11. Environmental assessment: Addition to operations building, Mars site

    NASA Technical Reports Server (NTRS)

    1990-01-01

    An Environmental Assessment was performed of the proposed addition to building G-86 at the Mars Site, which will provide space for new electronic equipment to consolidate the Deep Space Network (DSN) support facilities from other Goldstone Deep Space Communication Complex (GDSCC) sites at the Mars Site, and will include a fifth telemetry and command group with its associated link monitor, control processor, and operator consoles. The addition of these facilities will increase the capability of the DSN to support future sophisticated NASA spacecraft missions such as the International Solar and Terrestrial Physics (ISTP) Program. The planned construction of this building addition requires an Environmental Assessment (EA) document that records the existing environmental conditions at the Mars Site, that analyzes the environmental effects that possibly could be expected from the construction and use of the new building addition, and that recommends measures to be taken to mitigate any possible deleterious environmental effects.

  12. 77 FR 699 - Regulation of Fuels and Fuel Additives: Identification of Additional Qualifying Renewable Fuel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-05

    ...\\ For a similar discussion see page 46 of Stratton, R.W., Wong, H.M., Hileman, J.I. 2010. Lifecycle... submitting comments. Email: a-and-r[email protected] , Attention Air and Radiation Docket ID EPA-HQ-OAR-2011... protected through www.regulations.gov or email. The www.regulations.gov Web site is an ``anonymous access...

  13. Ionospheric Electron/Ion Densities Temperatures on CD-ROM and WWW

    NASA Technical Reports Server (NTRS)

    Bilitza, Dieter; Papitashvili, Natasha; Schar, Bill; Grebowsky, Joseph

    2002-01-01

    As part of this project a large volume of ionospheric satellite insitu data from the sixties, seventies and early eighties were made accessible online in ASCII format for public use. This includes 14 data sets from the BE-B, Alouette 2, DME-A, AE-B, ISIS-1, ISIS-2, OGO-6, DE-2, AEROS-A, AE-C, AE-D, AE-E, and Hinotori satellites. The original data existed in various machine-specific, highly compressed, binary encoding on 7-, or 9-track magnetic tapes. The data were decoded and converted to a common ASCII data format, solar and magnetic indices were added, and some quality control measures were taken. The original intent of producing CD-ROMs with these data was overtaken by the rapid development of the Internet. Most users now prefer to obtain the data directly online and greatly value WWW-interfaces to browse, plot and subset the data. Accordingly the data were made available online on the anonymous ftp site of NASA's National Space Science Data Center (NSSDC) at ftp://nssdcftp.gsfc.nasa.gov/spacecraft data/ and on NSSDC's ATMOWeb (http://nssdc.gsfc.nasa.gov/atmoweb/), a WWW-interface for plotting, subsetting, and downloading the data. Several new features were implemented into ATMOWeb as part of this project including a filtering and scatter plot capability. The availability of this new database and WWW system was announced through several electronic mailer (AGU, CEDAR, IRI, etc) and through talks and posters during scientific meetings.

  14. EPA True NO2 ground site measurements ?? multiple sites, TCEQ ground site measurements of meteorological and air pollution parameters ?? multiple sites ,GeoTASO NO2 Vertical Column

    EPA Pesticide Factsheets

    EPA True NO2 ground site measurements ?? multiple sites - http://www-air.larc.nasa.gov/cgi-bin/ArcView/discover-aq.tx-2013; TCEQ ground site measurements of meteorological and air pollution parameters ?? multiple sites - http://www-air.larc.nasa.gov/cgi-bin/ArcView/discover-aq.tx-2013; GeoTASO NO2 Vertical Column - http://www-air.larc.nasa.gov/cgi-bin/ArcView/discover-aq.tx-2013?FALCON=1This dataset is associated with the following publication:Nowlan, C., X. Lu, J. Leitch, K. Chance, G. González Abad, C. Lu, P. Zoogman, J. Cole, T. Delker, W. Good, F. Murcray, L. Ruppert, D. Soo, M. Follette-Cook, S. Janz, M. Kowalewski, C. Loughner, K. Pickering, J. Herman, M. Beaver, R. Long, J. Szykman, L. Judd, P. Kelley, W. Luke, X. Ren, and J. Al-Saadi. Nitrogen dioxide observations from the Geostationary Trace gas and Aerosol Sensor Optimization (GeoTASO) airborne instrument: Retrieval algorithm and measurements during DISCOVER-AQ Texas 2013. Atmospheric Measurement Techniques. Copernicus Publications, Katlenburg-Lindau, GERMANY, 9(6): 2647-2668, (2016).

  15. Comparing Commercial WWW Browsers.

    ERIC Educational Resources Information Center

    Notess, Greg R.

    1995-01-01

    Four commercial World Wide Web browsers are evaluated for features such as handling of WWW protocols and different URLs: FTP, Telnet, Gopher and WAIS, and e-mail and news; bookmark capabilities; navigation features; file management; and security support. (JKP)

  16. CFD Data Sets on the WWW for Education and Testing

    NASA Technical Reports Server (NTRS)

    Globus, Al; Lasinski, T. A. (Technical Monitor)

    1995-01-01

    The Numerical Aerodynamic Simulation (NAS) Systems Division at NASA Ames Research Center has begun the development of a Computational Fluid Dynamics (CFD) data set archive on the World Wide Web (WWW) at URL http://www.nas.nasa.gov/NAS/DataSets/. Data sets are integrated with related information such as research papers, metadata, visualizations, etc. In this paper, four classes of users are identified and discussed: students, visualization developers, CFD practitioners, and management. Bandwidth and security issues are briefly reviewed and the status of the archive as of May 1995 is examined. Routine network distribution of data sets is likely to have profound implications for the conduct of science. The exact nature of these changes is subject to speculation, but the ability for anyone to examine the data, in addition to the investigator's analysis, may well play an important role in the future.

  17. 20. Photographic copy of an asconstructed site plan for additions ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Photographic copy of an as-constructed site plan for additions to North Base: Job No. A(8-1), Military Construction, Materiel Command Flight Test Base, Muroc, California; Additional Construction, Location Plan, Sheet No. 2, October 1943. Reproduced from the holdings of the National Archives, Pacific Southwest Region - Edwards Air Force Base, North Base, North Base Road, Boron, Kern County, CA

  18. Thanks to 70 years of Inter American Statistical cooperation, the world's largest integrated census microdata dissemination site www.ipums.org/international.

    PubMed

    McCAA, Robert

    2013-06-01

    Seventy years of Inter American Statistical cooperation, symbolized by the 70 th anniversary of Estadística , made possible the construction of IPUMS-International, the world's largest integrated census microdata dissemination site, www.ipums.org/international. Currently, the site offers access to 238 samples totaling over 540 million person records representing 74 countries. The Americas, which account for only about one-seventh of the world's population, amount to over one-third (36%) of the person records in the IPUMS-International database. Likewise, 35% of the citations in the IPUMS-International bibliography are for studies focused on Latin America, with about half of these analyzing a single Latin American country. This article discusses salient features of the IPUMS integration methods and system. National Statistical Institutes that have not yet entrusted 2010 census microdata to the initiative are invited to do so. Researchers and teachers are invited to use the data freely in analysis and teaching. Setenta años de cooperación estadística inter-Americana, simbolizada por el 70 aniversario de la revista Estadística , han hecho posible la construcción de IPUMS-internacional, la base en línea de microdatos censales harmonizados más grande del mundo, www.ipums.org/international. Actualmente, IPUMS proporciona acceso a 238 muestras con más de 540 millones de registros individuales de 74 países. Las Américas, que albergan una séptima parte de la población mundial, representan más de un tercio (36%) de todos los registros individuales en la base de datos IPUMS-internacional. Asimismo, el 35% de todas las referencias en la bibliografía de IPUMS son de estudios realizados sobre América Latina, la mitad de éstas basadas en un sólo país de la región. Este artículo presenta las principales características del sistema de integración y difusión de datos de IPUMS. Los Institutos Nacionales de Estadísticas que todavía no ha entregado la muestra

  19. 18. Photographic copy of site plan for additions to North ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Photographic copy of site plan for additions to North Base: Job No. Muroc A(511), Military Construction, Third District Region, San Bernardino, California; Muroc Bombing Range, Muroc Lake, Calif; Additional Temporary Construction, Materiel Center Flight Test Base, Location Plan, February 1943. Reproduced from the holdings of the National Archives, Pacific Southwest Region - Edwards Air Force Base, North Base, North Base Road, Boron, Kern County, CA

  20. 19. Photographic copy of an asconstructed site plan for additions ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. Photographic copy of an as-constructed site plan for additions to North Base: Job No. Muroc A(511), Military Construction, Third District Region, San Bernardino, California; Muroc Bombing Range, Muroc Lake, Calif; Additional Temporary Construction, Materiel Center Flight Test Base, Location Grading & Paving Plan, Sheet No. 1 of 21, March 1943. Reproduced from the holdings of the National Archives, Pacific Southwest Region - Edwards Air Force Base, North Base, North Base Road, Boron, Kern County, CA

  1. Making Dynamic Digital Maps Cross-Platform and WWW Capable

    NASA Astrophysics Data System (ADS)

    Condit, C. D.

    2001-05-01

    High-quality color geologic maps are an invaluable information resource for educators, students and researchers. However, maps with large datasets that include images, or various types of movies, in addition to site locations where analytical data has been collected, are difficult to publish in a format that facilitates their easy access, distribution and use. The development of capable desktop computers and object oriented graphical programming environments has facilitated publication of such data sets in an encapsulated form. The original Dynamic Digital Map (DDM) programs, developed using the Macintosh based SuperCard programming environment, exemplified this approach, in which all data are included in a single package designed so that display and access to the data did not depend on proprietary programs. These DDMs were aimed for ease of use, and allowed data to be displayed by several methods, including point-and-click at icons pin-pointing sample (or image) locations on maps, and from clicklists of sample or site numbers. Each of these DDMs included an overview and automated tour explaining the content organization and program use. This SuperCard development culminated in a "DDM Template", which is a SuperCard shell into which SuperCard users could insert their own content and thus create their own DDMs, following instructions in an accompanying "DDM Cookbook" (URL http://www.geo.umass.edu/faculty/condit/condit2.html). These original SuperCard-based DDMs suffered two critical limitations: a single user platform (Macintosh) and, although they can be downloaded from the web, their use lacked an integration into the WWW. Over the last eight months I have been porting the DDM technology to MetaCard, which is aggressively cross-platform (11 UNIX dialects, WIN32 and Macintosh). The new MetaCard DDM is redesigned to make the maps and images accessible either from CD or the web, using the "LoadNGo" concept. LoadNGo allows the user to download the stand-alone DDM

  2. Thanks to 70 years of Inter American Statistical cooperation, the world’s largest integrated census microdata dissemination site www.ipums.org/international

    PubMed Central

    McCAA, ROBERT

    2014-01-01

    Seventy years of Inter American Statistical cooperation, symbolized by the 70th anniversary of Estadística, made possible the construction of IPUMS-International, the world’s largest integrated census microdata dissemination site, www.ipums.org/international. Currently, the site offers access to 238 samples totaling over 540 million person records representing 74 countries. The Americas, which account for only about one-seventh of the world’s population, amount to over one-third (36%) of the person records in the IPUMS-International database. Likewise, 35% of the citations in the IPUMS-International bibliography are for studies focused on Latin America, with about half of these analyzing a single Latin American country. This article discusses salient features of the IPUMS integration methods and system. National Statistical Institutes that have not yet entrusted 2010 census microdata to the initiative are invited to do so. Researchers and teachers are invited to use the data freely in analysis and teaching. Setenta años de cooperación estadística inter-Americana, simbolizada por el 70 aniversario de la revista Estadística, han hecho posible la construcción de IPUMS-internacional, la base en línea de microdatos censales harmonizados más grande del mundo, www.ipums.org/international. Actualmente, IPUMS proporciona acceso a 238 muestras con más de 540 millones de registros individuales de 74 países. Las Américas, que albergan una séptima parte de la población mundial, representan más de un tercio (36%) de todos los registros individuales en la base de datos IPUMS-internacional. Asimismo, el 35% de todas las referencias en la bibliografía de IPUMS son de estudios realizados sobre América Latina, la mitad de éstas basadas en un sólo país de la región. Este artículo presenta las principales características del sistema de integración y difusión de datos de IPUMS. Los Institutos Nacionales de Estadísticas que todavía no ha entregado la muestra

  3. A WWW-based information system on resistance of bacteria to antibiotics.

    PubMed

    Schindler, J; Schindler, Z; Schindler, J

    1998-01-01

    The information system on resistance of bacteria to antibiotics (WARN--World Antibiotic Resistance Network) is implemented as a WWW server at Charles University in Prague (http:/(/)www.warn.cas.cz). Its main goal is to give information about problems of antibiotic resistance of bacteria and to process data on isolated strains. The WARN web-site contains six main topics. Four of them form the core of the system: Topics of Interest bring information on selected timely topics in antibiotic resistance--pneumococci, staphylococci, beta-lactamases, glycopeptide--and aminoglycoside resistance. Global Monitor brings references and reports on resistance in the world as well as recommended method of surveillance. The topic Data contains raw data on strains in particular countries and hospitals. Data can be viewed in their original form as a list of records (strains) or processed to provide statistics about the resistance rates in the selected country or hospital respectively. The topic Search allows one to search for one or several terms in the whole document. Counts of accessed pages show, that there is a standing demand for information about the serious problems of antibiotic therapy of infectious diseases.

  4. Internet resources for dentistry: government and medical sites for the dental professional.

    PubMed

    Guest, G F

    2000-02-15

    As society transitions deeper into the Information Age, Information Technology has become a critical tool that supports all facets of the global economy. The Internet, via the World-Wide Web (WWW), has become a major component of business operations for corporate and educational organizational entities. An estimated 10,000 or more health-related websites are providing information for both consumers and healthcare professionals. In addition to private and state-supported institutions being present on the Internet, the federal government has moved rapidly toward disseminating information electronically, with significant utilization of the WWW as the technological vehicle. All branches of the US Government and federal-related agencies are now represented on the Internet in an effort to deliver content to their end users, primarily the public. The intent of this article is to complement the previous publication, "Internet Resources for Dentistry: Utilization of the Internet to Support Professional Growth, Decision Making, and Patient Care," by presenting dental healthcare professionals with information on additional governmental and medical "Internet" sites. In addition, healthcare professionals must arm themselves with more than just access itself, but also the ability to critically judge the quality of information retrieved from the WWW.

  5. WWW database of optical constants for astronomy

    NASA Astrophysics Data System (ADS)

    Henning, Th.; Il'In, V. B.; Krivova, N. A.; Michel, B.; Voshchinnikov, N. V.

    1999-04-01

    The database we announce contains references to the papers, data files and links to the Internet resources related to measurements and calculations of the optical constants of the materials of astronomical interest: different silicates, ices, oxides, sulfides, carbides, carbonaceous species from amorphous carbon to graphite and diamonds, etc. We describe the general structure and content of the database which has now free access via Internet: http://www.astro.spbu.ru/JPDOC/entry.html\\ or \\ http:// www. astro.uni-jena.de/Users/database/entry.html

  6. Using the WWW to Make YOHKOH SXT Images Available to the Public: The YOHKOH Public Outreach Project

    NASA Astrophysics Data System (ADS)

    Larson, M.; McKenzie, D.; Slater, T.; Acton, L.; Alexander, D.; Freeland, S.; Lemen, J.; Metcalf, T.

    1997-05-01

    The Yohkoh Public Outreach Project (YPOP) is funded by NASA as one of the Information Infrastructure Technology and Applications Cooperative Agreement Teams to create public access to high quality Yohkoh SXT data via the World Wide Web. These products are being made available to the scientific research community, K-12 schools, and informal education centers including planetaria, museums, and libraries. The project aims to utilize the intrinsic excitement of the SXT data, and in particular the SXT movies, to develop science learning tools and classroom activities. The WWW site at URL: http://www.space.lockheed.com/YPOP/ uses a movie theater theme to highlight available Yohkoh movies in a non-intimidating and entertaining format for non-scientists. The site features lesson plans, 'solar' activities, slide shows and, of course, a variety of movies about the Sun. Classroom activities are currently undergoing development with a team of scientists and K-12 teachers for distribution in late 1997. We will display the products currently online, which include a solar classroom with activities for teachers, background resources, and a virtual tour of our Sun.

  7. Developing a WWW Resource Centre for Acquiring and Accessing Open Learning Materials on Research Methods (ReMOTE).

    ERIC Educational Resources Information Center

    Newton, Robert; Marcella, Rita; Middleton, Iain; McConnell, Michael

    This paper reports on ReMOTE (Research Methods Online Teaching Environment), a Robert Gordon University (Scotland) project focusing on the development of a World Wide Web (WWW) site devoted to the teaching of research methods. The aim of ReMOTE is to provide an infrastructure that allows direct links to specialist sources in order to enable the…

  8. 15 CFR 921.33 - Boundary changes, amendments to the management plan, and addition of multiple-site components.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... management plan, and addition of multiple-site components. 921.33 Section 921.33 Commerce and Foreign Trade... management plan, and addition of multiple-site components. (a) Changes in the boundary of a Reserve and major... management plan shall address goals and objectives for all components of the multi-site Reserve and the...

  9. 36 CFR 6.6 - Solid waste disposal sites within new additions to the National Park System.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... within new additions to the National Park System. 6.6 Section 6.6 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SOLID WASTE DISPOSAL SITES IN UNITS OF THE NATIONAL PARK SYSTEM § 6.6 Solid waste disposal sites within new additions to the National Park System. (a) An operator...

  10. 36 CFR 6.6 - Solid waste disposal sites within new additions to the National Park System.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... within new additions to the National Park System. 6.6 Section 6.6 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SOLID WASTE DISPOSAL SITES IN UNITS OF THE NATIONAL PARK SYSTEM § 6.6 Solid waste disposal sites within new additions to the National Park System. (a) An operator...

  11. 36 CFR 6.6 - Solid waste disposal sites within new additions to the National Park System.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... within new additions to the National Park System. 6.6 Section 6.6 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SOLID WASTE DISPOSAL SITES IN UNITS OF THE NATIONAL PARK SYSTEM § 6.6 Solid waste disposal sites within new additions to the National Park System. (a) An operator...

  12. 75 FR 816 - Identification of Additional Classes of Facilities for Development of Financial Responsibility...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-06

    ... protected through www.regulations.gov or e-mail. The www.regulations.gov Web site is an ``anonymous access... Can I Get Copies of This Document and Other Related Information? This Federal Register notice and.... EPA-HQ-SFUND-2009-0834. All documents in the docket are listed on the http://www.regulations.gov Web...

  13. Prediction of proprotein convertase cleavage sites.

    PubMed

    Duckert, Peter; Brunak, Søren; Blom, Nikolaj

    2004-01-01

    Many secretory proteins and peptides are synthesized as inactive precursors that in addition to signal peptide cleavage undergo post-translational processing to become biologically active polypeptides. Precursors are usually cleaved at sites composed of single or paired basic amino acid residues by members of the subtilisin/kexin-like proprotein convertase (PC) family. In mammals, seven members have been identified, with furin being the one first discovered and best characterized. Recently, the involvement of furin in diseases ranging from Alzheimer's disease and cancer to anthrax and Ebola fever has created additional focus on proprotein processing. We have developed a method for prediction of cleavage sites for PCs based on artificial neural networks. Two different types of neural networks have been constructed: a furin-specific network based on experimental results derived from the literature, and a general PC-specific network trained on data from the Swiss-Prot protein database. The method predicts cleavage sites in independent sequences with a sensitivity of 95% for the furin neural network and 62% for the general PC network. The ProP method is made publicly available at http://www.cbs.dtu.dk/services/ProP.

  14. Development of a laboratory niche Web site.

    PubMed

    Dimenstein, Izak B; Dimenstein, Simon I

    2013-10-01

    This technical note presents the development of a methodological laboratory niche Web site. The "Grossing Technology in Surgical Pathology" (www.grossing-technology.com) Web site is used as an example. Although common steps in creation of most Web sites are followed, there are particular requirements for structuring the template's menu on methodological laboratory Web sites. The "nested doll principle," in which one object is placed inside another, most adequately describes the methodological approach to laboratory Web site design. Fragmentation in presenting the Web site's material highlights the discrete parts of the laboratory procedure. An optimally minimal triad of components can be recommended for the creation of a laboratory niche Web site: a main set of media, a blog, and an ancillary component (host, contact, and links). The inclusion of a blog makes the Web site a dynamic forum for professional communication. By forming links and portals, cloud computing opens opportunities for connecting a niche Web site with other Web sites and professional organizations. As an additional source of information exchange, methodological laboratory niche Web sites are destined to parallel both traditional and new forms, such as books, journals, seminars, webinars, and internal educational materials. Copyright © 2013 Elsevier Inc. All rights reserved.

  15. 77 FR 9219 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-16

    ...: Office of Scientific and Technical Information, 1 Science.gov Way, Oak Ridge, Tennessee 37830. FOR... email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em/ssab . SUPPLEMENTARY... be available at the following Web site: http://www.oakridge.doe.gov/em/ssab/minutes.htm . Issued at...

  16. 77 FR 29996 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ...: Department of Energy Information Center, 1 Science.gov Way, Oak Ridge, Tennessee 37830. FOR [email protected]gov or check the Web site at www.oakridge.doe.gov/em/ssab . SUPPLEMENTARY INFORMATION: Purpose... also be available at the following Web site: http://www.oakridge.doe.gov/em/ssab/minutes.htm . Issued...

  17. 77 FR 64494 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-22

    ...: Department of Energy Information Center, Office of Science and Technical Information, 1 Science.gov Way, Oak...-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em... following Web site: http://www.oakridge.doe.gov/em/ssab/minutes.htm . [[Page 64495

  18. 77 FR 49442 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-16

    ...: Department of Energy Information Center, Office of Science and Technical Information, 1 Science.gov Way, Oak...-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em... following Web site: http://www.oakridge.doe.gov/em/ssab/minutes.htm . [[Page 49443

  19. 78 FR 23241 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-18

    ... of Energy Information Center, Office of Science and Technical Information, 1 Science.gov Way, Oak...-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em... also be available at the following Web site: http://www.oakridge.doe.gov/em/ssab/minutes.htm . Issued...

  20. 36 CFR 6.6 - Solid waste disposal sites within new additions to the National Park System.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Solid waste disposal sites... NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SOLID WASTE DISPOSAL SITES IN UNITS OF THE NATIONAL PARK SYSTEM § 6.6 Solid waste disposal sites within new additions to the National Park System. (a) An operator...

  1. 36 CFR 6.6 - Solid waste disposal sites within new additions to the National Park System.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Solid waste disposal sites... NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR SOLID WASTE DISPOSAL SITES IN UNITS OF THE NATIONAL PARK SYSTEM § 6.6 Solid waste disposal sites within new additions to the National Park System. (a) An operator...

  2. The New WWW: Whatever, Whenever, Wherever

    ERIC Educational Resources Information Center

    March, Tom

    2006-01-01

    We are entering an age of instant media gratification, in which a "multimedia aura" will "accompany us wherever we go," writes Tom March. The New WWW, says March, offers us whatever we want, whenever and wherever we want it. The effect on our children may be unrealistic expectations, premature disillusionment, and unhappiness. To counterbalance…

  3. 78 FR 49738 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-15

    ...: Department of Energy Information Center, Office of Science and Technical Information, 1 Science.gov Way, Oak...-3315; Fax (865) 576-0956 or email: n[email protected]gov or check the Web site at www.oakridge.doe.gov/em... following Web site: http://www.oakridge.doe.gov/em/ssab/board-minutes.html . Issued at Washington, DC, on...

  4. 78 FR 58292 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ...: Department of Energy Information Center, Office of Science and Technical Information, 1 Science.gov Way, Oak...-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em... above. Minutes will also be available at the following Web site: http://www.oakridge.doe.gov/em/ssab...

  5. 77 FR 58364 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ...: Department of Energy Information Center, Office of Science and Technical Information, 1 Science.gov Way, Oak...-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em... following Web site: http://www.oakridge.doe.gov/em/ssab/minutes.htm . Issued at Washington, DC, on September...

  6. 78 FR 17648 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ...: Department of Energy Information Center, Office of Science and Technical Information, 1 Science.gov Way, Oak...-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em... following Web site: http://www.oakridge.doe.gov/em/ssab/minutes.htm . Issued at Washington, DC, on March 15...

  7. 78 FR 3890 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-17

    ...: Department of Energy Information Center, Office of Science and Technical Information, 1 Science.gov Way, Oak...-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em... following Web site: http://www.oakridge.doe.gov/em/ssab/minutes.htm . Issued at Washington, DC on January 11...

  8. 78 FR 12746 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-25

    ...: Department of Energy Information Center, Office of Science and Technical Information, 1 Science.gov Way, Oak...-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em... above. Minutes will also be available at the following Web site: http://www.oakridge.doe.gov/em/ssab...

  9. 77 FR 74836 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-18

    ...: Department of Energy Information Center, Office of Science and Technical Information, 1 Science.gov Way, Oak...-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em... above. Minutes will also be available at the following Web site: http://www.oakridge.doe.gov/em/ssab...

  10. 78 FR 30911 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    ...: Department of Energy Information Center, Office of Science and Technical Information, 1 Science.gov Way, Oak...-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em... following Web site: http://www.oakridge.doe.gov/em/ssab/board-minutes.html . Issued at Washington, DC, on...

  11. PhosphoBase: a database of phosphorylation sites.

    PubMed Central

    Blom, N; Kreegipuu, A; Brunak, S

    1998-01-01

    PhosphoBase is a database of experimentally verified phosphorylation sites. Version 1.0 contains 156 entries and 398 experimentally determined phosphorylation sites. Entries are compiled and revised from the literature and from major protein sequence databases such as SwissProt and PIR. The entries provide information about the phosphoprotein and the exact position of its phosphorylation sites. Furthermore, part of the entries contain information about kinetic data obtained from enzyme assays on specific peptides. To illustrate the use of data extracted from PhosphoBase we present a sequence logo displaying the overall conservation of positions around serines phosphorylated by protein kinase A (PKA). PhosphoBase is available on the WWW at http://www.cbs.dtu.dk/databases/PhosphoBase/ PMID:9399879

  12. A movie of the RNA polymerase nucleotide addition cycle.

    PubMed

    Brueckner, Florian; Ortiz, Julio; Cramer, Patrick

    2009-06-01

    During gene transcription, RNA polymerase (Pol) passes through repetitive cycles of adding a nucleotide to the growing mRNA chain. Here we obtained a movie of the nucleotide addition cycle by combining structural information on different functional states of the Pol II elongation complex (EC). The movie illustrates the two-step loading of the nucleoside triphosphate (NTP) substrate, closure of the active site for catalytic nucleotide incorporation, and the presumed two-step translocation of DNA and RNA, which is accompanied by coordinated conformational changes in the polymerase bridge helix and trigger loop. The movie facilitates teaching and a mechanistic analysis of transcription and can be downloaded from http://www.lmb.uni-muenchen.de/cramer/pr-materials.

  13. How to use the WWW to distribute STI

    NASA Technical Reports Server (NTRS)

    Roper, Donna G.

    1994-01-01

    This presentation explains how to use the World Wide Web (WWW) to distribute scientific and technical information as hypermedia. WWW clients and servers use the HyperText Transfer Protocol (HTTP) to transfer documents containing links to other text, graphics, video, and sound. The standard language for these documents is the HyperText MarkUp Language (HTML). These are simply text files with formatting codes that contain layout information and hyperlinks. HTML documents can be created with any text editor or with one of the publicly available HTML editors or convertors. HTML can also include links to available image formats. This presentation is available online. The URL is http://sti.larc.nasa. (followed by) gov/demos/workshop/introtext.html.

  14. 77 FR 74266 - Review of National Environmental Policy Act Categorical Exclusion Survey Posted on DOT/FHWA Web Site

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    ... of National Environmental Policy Act Categorical Exclusion Survey Posted on DOT/FHWA Web Site AGENCY... review is now available on the FHWA Web site, http://www.fhwa.dot.gov/map21 , and FTA Web site, http://www.fta.dot.gov/map21 . DATES: These reports were posted on the Web site on December 7, 2012...

  15. Hosting an `Ask the Astronomer' Site on the Internet

    NASA Astrophysics Data System (ADS)

    Odenwald, S. F.

    1996-12-01

    Since 1995, the World Wide Web has explosively evolved into a significant medium for dispensing astronomical information to the general public. In addition to the numerous image archives that have proliferated, an increasing number of sites invite visitors to pose questions about astronomy and receive answers provided by professional astronomers. In this paper, I describe the operation of an Ask the Astronomer site that was opened on the WWW during August, 1995 as part of an astronomy education resource area called the "Astronomy Cafe" (URL=http://www2.ari.net/home/odenwald/cafe.html). The Astronomy Cafe includes a number of documents describing: a career in astronomy; how research papers are written; essays about cosmology, hyperspace and infrared astronomy; and the results from a 100-question, just for fun, personality test which distinguishes astronomers from non-astronomers. The Ask the Astronomer site is operated by a single astronomer through private donations and is now approaching its 500th day of operation. It contains over 2000+ questions and answers with a growth rate of 5 - 10 questions per day. It has attracted 70,000 visitors who are responsible for nearly 1 million 'hits' during the site's lifetime. The monthly statistics provide a unique survey of the kinds of individuals and organizations who visit Ask the Astronomer-type web sites, moreover, the accumulated questions provide a diagnostic X-ray into the public mind in the area of astronomy. I will present an analysis of the user demographics, and the types of questions that appear to be the most frequently asked. A paper copy of the complete index of these questions will be available for inspection.

  16. 78 FR 63171 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-23

    ...: Department of Energy Information Center, Office of Science and Technical Information, 1 Science.gov Way, Oak...-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em... above. Minutes will also be available at the following Web site: http://www.oakridge.doe.gov/em/ssab...

  17. Climate Web sites

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    With the growing interest in extreme climate and weather events, the National Oceanic and Atmospheric Administration (NOAA) has set up a one-stop Web site. It includes data on tornadoes, hurricanes, and heavy rainfall, temperature extremes, global climate change, satellite images, and El Niño and La Niña. The Web address is http://www.ncdc.noaa.gov.Another good climate Web site is the La Niña Home Page. Set up by the Environmental and Societal Impacts Group of the National Center for Atmospheric Research, the site includes forecasts, data sources, impacts, and Internet links.

  18. In Brief: Red tide Web site

    NASA Astrophysics Data System (ADS)

    Showstack, Randy; Kumar, Mohi

    2008-06-01

    The U.S. National Oceanic and Atmospheric Administration has established the NOAA New England Red Tide Information Center to help people understand the significant red tides that are predicted to form there later this spring. The site (http://www.oceanservice.noaa.gov/redtide) will provide a summary of the current red tide situation and its potential harmful impacts on humans and animals and will serve as a central repository of information. The site also will have direct links to news releases, changes to relevant federal fishing regulations, links to closures of shellfish waters, and links to state agency Web sites with localized information. In addition, the site will have information about NOAA's scientific response effort as well as information from several other sources including NOAA's major response partner, the Woods Hole Oceanographic Institution (WHOI). On 24 April, WHOI scientists, using forecast models developed with NOAA funding support, predicted ``that excess winter precipitation has set the stage for a harmful algal bloom similar to the historic red tide of 2005.'' That bloom shut down shellfish beds from the Bay of Fundy to Martha's Vineyard for several months.

  19. www.studentthink.molecularbiology.

    ERIC Educational Resources Information Center

    Morvillo, Nancy; Schmidt, Matthew; Carlson, Albert

    2000-01-01

    Describes a microbiology exercise that is designed to expose students to the world wide web. Introduces a molecular biology quiz site and National Center for Biotechnology Information (NCBI). Provides a list of molecular biology sites on the Internet. (YDS)

  20. Organization and dissemination of multimedia medical databases on the WWW.

    PubMed

    Todorovski, L; Ribaric, S; Dimec, J; Hudomalj, E; Lunder, T

    1999-01-01

    In the paper, we focus on the problem of building and disseminating multimedia medical databases on the World Wide Web (WWW). The current results of the ongoing project of building a prototype dermatology images database and its WWW presentation are presented. The dermatology database is part of an ambitious plan concerning an organization of a network of medical institutions building distributed and federated multimedia databases of a much wider scale.

  1. 17 CFR 230.493 - Additional Schedule B disclosure and filing requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... disclose in its Schedule B registration statement: (1) That the Commission maintains an Internet site that... (2) The address for the Commission Internet site (http://www.sec.gov). A foreign government or political subdivision filing on EDGAR is further encouraged to give its Internet address, if available. [67...

  2. Nuclear Data on the WWW

    NASA Astrophysics Data System (ADS)

    Firestone, Richard B.; Chu, S. Y. Frank; Ekstrom, L. Peter; Wu, Shiu-Chin; Singh, Balraj

    1997-10-01

    The Isotopes Project is developing Internet home pages to provide data for radioactive decay, nuclear structure, nuclear astrophysics, spontaneous fission, thermal neutron capture, and atomic masses. These home pages can be accessed from the Table of Isotopes home page at http://isotopes.lbl.gov/isotopes/toi.html. Data from the Evaluated Nuclear Structure Data File (ENSDF) is now available on the WWW in Nuclear Data Sheet style tables, complete with comments and hypertext linked footnotes. Bibliographic information from the Nuclear Science Reference (NSR) file can be searched on the WWW by combinations of author, A, Z, reaction, and various keywords. Decay gamma-ray data from several databases can be searched by energy. The Table of Superdeformed Nuclear Bands and Fission Isomers is continously updated. Reaction rates from Hoffman and Woosley and from Thielemann, fission yields from England and Rider, thermal neutron cross-sections from BNL-325, atomic masses from Audi, and skeleton scheme drawings and nuclear charts from the Table of Isotopes are among the information available through these websites. The nuclear data home pages are accessed by over 3500 different users each month.

  3. User Interface Design for WWW-Based Courses: Building upon Student Evaluations.

    ERIC Educational Resources Information Center

    van Rennes, Linda; Collis, Betty

    This paper describes how student reactions shaped the design of a WWW (World Wide Web)-based course environment at the University of Twente (Netherlands), using the example of a first year course. The first section discusses the importance of user interface (re)design for WWW-based courses. The University's focus on student evaluations of…

  4. 9 CFR 392.9 - Availability of additional guidance.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... 392.9 Section 392.9 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FOOD SAFETY AND INSPECTION SERVICE ADMINISTRATIVE PROVISIONS PETITIONS FOR RULEMAKING § 392.9... rulemaking may be found on the FSIS Web site at http://www/fsis.usda.gov/. ...

  5. The fate of prospective spine studies registered on www.ClinicalTrials.gov.

    PubMed

    Ohnmeiss, Donna D

    2015-03-01

    There has been concern expressed about research ethics with respect to not fully reporting data collected during clinical studies. One site available for all clinical trials is ClinicalTrials.gov. The original purpose of this site was to facilitate patients seeking a trial for the treatment of their particular condition. The internationally available site offers general information about the study, sponsor name, principal investigator, patient selection criteria, enrollment goal, study design, outcome measures, participating centers, initiation date, date posted, date completed, and other pertinent data. The site can be used to identify studies conducted for a particular condition or intervention. The purpose of this study was to investigate the fate of spine-related studies registered on www.ClinicalTrials.gov, with particular focus on the publication rate of completed trials. Analysis and classification of clinical studies posted on an international research registry Web page and literature search for related publications. Not applicable. The primary outcome measure was publication of the study registered on ClinicalTrials.gov. Multiple searches were conducted on ClinicalTrials.gov Web site to identify studies related to commonly treated spinal conditions, including herniated disc, degenerative disc disease, stenosis, and spondylolisthesis. Studies related to tumors, fractures, or that included nonspine conditions were not included. For studies classified as completed more than 18 months before this review, literature searches were conducted to determine if the results of the study had been published and factors related to publication. The author has no financial conflict related to this work. There were 263 spine-related studies identified from searches on the ClinicalTrials.gov site. Data on the site had the studies classified as follows: 72 completed, 70 active, not recruiting (generally indicates collecting follow-up data), 74 recruiting, 11 recruiting by

  6. Phase Structure and Site Preference Behavior of Ternary Alloying Additions to PdTi and PtTi Shape-Memory Alloys

    NASA Technical Reports Server (NTRS)

    Bozzolo, Guillermo; Mosca, Hugo O.; Noebe, Ronald D.

    2006-01-01

    The phasc structure and concentration dependence of the lattice parameter and energy of formation of ternary Pd-'I-X and Pt-Ti-X alloys for a large number of ternary alloying additions X (X = Na, Mg, Al, Si, Sc. V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Y, Zr, Nb, Mo, Tc, Ru, Rh, Ag, Cd, Hf, Ta, W, Re, Os, Ir) are investigated with an atomistic modeling approach. In addition, a detailed description of the site preference behavior of such additions showing that the elements can be grouped according to their absolute preference for a specific site, regardless of concentration, or preference for available sites in the deficient sublattice is provided.

  7. WWW.2CHEAT.COM.

    ERIC Educational Resources Information Center

    Rooks, Clay D.

    This paper addresses the subject of cheating and plagiarism via the World Wide Web. After spending just a few hours browsing on the Internet, the author found dozens of "cheat" sites that offered term papers of all kinds. Some sites charge a fee for papers, some sites only request that students join by sending in one of their papers to add to the…

  8. 12 CFR 4.4 - Washington office and web site.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Washington office and web site. 4.4 Section 4.4... EXAMINERS Organization and Functions § 4.4 Washington office and web site. The Washington office of the OCC...'s Web site is at http://www.occ.gov. [76 FR 43561, July 21, 2011] ...

  9. 12 CFR 4.4 - Washington office and web site.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Washington office and web site. 4.4 Section 4.4... EXAMINERS Organization and Functions § 4.4 Washington office and web site. The Washington office of the OCC...'s Web site is at http://www.occ.gov. [76 FR 43561, July 21, 2011] ...

  10. 12 CFR 4.4 - Washington office and web site.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Washington office and web site. 4.4 Section 4.4... EXAMINERS Organization and Functions § 4.4 Washington office and web site. The Washington office of the OCC...'s Web site is at http://www.occ.gov. [76 FR 43561, July 21, 2011] ...

  11. Russian and CIS Library Internet Service: An Analysis of WWW-Server Development.

    ERIC Educational Resources Information Center

    Shraiberg, Yakov

    This paper traces the expansion of the Internet into Russian and Commonwealth of Independent States (CIS) libraries from basic access to the development of World Wide Web (WWW) servers. An analysis of the most representative groups of library WWW-servers arranged by projects, by corporate library network, or by geographical characteristics is…

  12. Nevada Test Site Environmental Report 2008

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cathy A. Wills

    2009-09-01

    The Nevada Test Site Environmental Report (NTSER) 2008 was prepared to meet the information needs of the public and the requirements and guidelines of the U.S. Department of Energy (DOE) for annual site environmental reports. It was prepared by National Security Technologies, LLC (NSTec), for the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO). This and previous years’ NTSERs are posted on the NNSA/NSO website at http://www.nv.doe.gov/library/publications/aser.aspx.

  13. Integrating WWW Technology into Classroom Teaching: College Students' Perceptions of Course Web Sites as an Instructional Resource.

    ERIC Educational Resources Information Center

    El-Tigi, Manal Aziz-El-Din

    This study examined college students' perceptions of course Web sites as an instructional resource for classroom-based courses. The focus was on identifying functions on the sites that students perceived as supporting and fostering their learning experiences. Subjects were 142 students responding to a 60-item questionnaire and open-ended…

  14. New Research Site to Launch in June

    NASA Astrophysics Data System (ADS)

    Zielinski, Sarah

    2007-05-01

    Thirteen science and technology societies will launch a new Web site (http://www.scitopia.org) in June that will enable users to search more than three million journal articles, conference proceedings, and patents at once.

  15. Ocean Drilling Program: Related Sites

    Science.gov Websites

    ) 306-0390 Web site: www.nsf.gov Joint Oceanographic Institutions for Deep Earth Sampling (JOIDES) US Members: Columbia University, Lamont-Doherty Earth Observatory Florida State University Oregon State University, College of Oceanic and Atmospheric Sciences Pennsylvania State University, College of Earth and

  16. Additional disturbances as a beneficial tool for restoration of post-mining sites: a multi-taxa approach.

    PubMed

    Řehounková, Klára; Čížek, Lukáš; Řehounek, Jiří; Šebelíková, Lenka; Tropek, Robert; Lencová, Kamila; Bogusch, Petr; Marhoul, Pavel; Máca, Jan

    2016-07-01

    Open interior sands represent a highly threatened habitat in Europe. In recent times, their associated organisms have often found secondary refuges outside their natural habitats, mainly in sand pits. We investigated the effects of different restoration approaches, i.e. spontaneous succession without additional disturbances, spontaneous succession with additional disturbances caused by recreational activities, and forestry reclamation, on the diversity and conservation values of spiders, beetles, flies, bees and wasps, orthopterans and vascular plants in a large sand pit in the Czech Republic, Central Europe. Out of 406 species recorded in total, 112 were classified as open sand specialists and 71 as threatened. The sites restored through spontaneous succession with additional disturbances hosted the largest proportion of open sand specialists and threatened species. The forestry reclamations, in contrast, hosted few such species. The sites with spontaneous succession without disturbances represent a transition between these two approaches. While restoration through spontaneous succession favours biodiversity in contrast to forestry reclamation, additional disturbances are necessary to maintain early successional habitats essential for threatened species and open sand specialists. Therefore, recreational activities seem to be an economically efficient restoration tool that will also benefit biodiversity in sand pits.

  17. Telomere formation on macronuclear chromosomes of Oxytricha trifallax and O. fallax: alternatively processed regions have multiple telomere addition sites

    PubMed Central

    Williams, Kevin R; Doak, Thomas G; Herrick, Glenn

    2002-01-01

    Background Ciliates employ massive chromatid breakage and de novo telomere formation during generation of the somatic macronucleus. Positions flanking the 81-MAC locus are reproducibly cut. But those flanking the Common Region are proposed to often escape cutting, generating three nested macronuclear chromosomes, two retaining "arms" still appended to the Common Region. Arm-distal positions must differ (in cis) from the Common Region flanks. Results The Common-Region-flanking positions also differ from the arm-distal positions in that they are "multi-TAS" regions: anchored PCR shows heterogeneous patterns of telomere addition sites, but arm-distal sites do not. The multi-TAS patterns are reproducible, but are sensitive to the sequence of the allele being processed. Thus, random degradation following chromatid cutting does not create this heterogeneity; these telomere addition sites also must be dictated by cis-acting sequences. Conclusions Most ciliates show such micro-heterogeneity in the precise positions of telomere addition sites. Telomerase is believed to be tightly associated with, and act in concert with, the chromatid-cutting nuclease: heterogeneity must be the result of intervening erosion activity. Our "weak-sites" hypothesis explains the correlation between alternative chromatid cutting at the Common Region boundaries and their multi-TAS character: when the chromatid-breakage machine encounters either a weak binding site or a weak cut site at these regions, then telomerase dissociates prematurely, leaving the new end subject to erosion by an exonuclease, which pauses at cis-acting sequences; telomerase eventually heals these resected termini. Finally, we observe TAS positioning influenced by trans-allelic interactions, reminiscent of transvection. PMID:12199911

  18. Systematic Site Characterization at Seismic Stations combined with Empirical Spectral Modeling: critical data for local hazard analysis

    NASA Astrophysics Data System (ADS)

    Michel, Clotaire; Hobiger, Manuel; Edwards, Benjamin; Poggi, Valerio; Burjanek, Jan; Cauzzi, Carlo; Kästli, Philipp; Fäh, Donat

    2016-04-01

    The Swiss Seismological Service operates one of the densest national seismic networks in the world, still rapidly expanding (see http://www.seismo.ethz.ch/monitor/index_EN). Since 2009, every newly instrumented site is characterized following an established procedure to derive realistic 1D VS velocity profiles. In addition, empirical Fourier spectral modeling is performed on the whole network for each recorded event with sufficient signal-to-noise ratio. Besides the source characteristics of the earthquakes, statistical real time analyses of the residuals of the spectral modeling provide a seamlessly updated amplification function w.r. to Swiss rock conditions at every station. Our site characterization procedure is mainly based on the analysis of surface waves from passive experiments and includes cross-checks of the derived amplification functions with those obtained through spectral modeling. The systematic use of three component surface-wave analysis, allowing the derivation of both Rayleigh and Love waves dispersion curves, also contributes to the improved quality of the retrieved profiles. The results of site characterisation activities at recently installed strong-motion stations depict the large variety of possible effects of surface geology on ground motion in the Alpine context. Such effects range from de-amplification at hard-rock sites to amplification up to a factor of 15 in lacustrine sediments with respect to the Swiss reference rock velocity model. The derived velocity profiles are shown to reproduce observed amplification functions from empirical spectral modeling. Although many sites are found to exhibit 1D behavior, our procedure allows the detection and qualification of 2D and 3D effects. All data collected during the site characterization procedures in the last 20 years are gathered in a database, implementing a data model proposed for community use at the European scale through NERA and EPOS (www.epos-eu.org). A web stationbook derived from it

  19. Biological Soil Crust Web Site

    Science.gov Websites

    www.soilcrust.org Crust 101 Advanced Gallery References CCERS site Links Biological Soil Crusts Textbook Corrections Level of Development Index Biological soil crusts are the community of organisms , mosses, liverworts and lichens. A Field Guide to Biological Soil Crusts of Western U.S. Drylands: Common

  20. WIND Toolkit Power Data Site Index

    DOE Data Explorer

    Draxl, Caroline; Mathias-Hodge, Bri

    2016-10-19

    This spreadsheet contains per-site metadata for the WIND Toolkit sites and serves as an index for the raw data hosted on Globus connect (nrel#globus:/globusro/met_data). Aside from the metadata, per site average power and capacity factor are given. This data was prepared by 3TIER under contract by NREL and is public domain. Authoritative documentation on the creation of the underlying dataset is at: Final Report on the Creation of the Wind Integration National Dataset (WIND) Toolkit and API: http://www.nrel.gov/docs/fy16osti/66189.pdf

  1. CancerNet redistribution via WWW.

    PubMed

    Quade, G; Püschel, N; Far, F

    1996-01-01

    CancerNet from the National Cancer Institute contains nearly 500 ASCII-files, updated monthly, with up-to-date information about cancer and the "Golden Standard" in tumor therapy. Perl scripts are used to convert these files to HTML-documents. A complex algorithm, using regular expression matching and extensive exception handling, detects headlines, listings and other constructs of the original ASCII-text and converts them into their HTML-counterparts. A table of contents is also created during the process. The resulting files are indexed for full-text search via WAIS. Building the complete CancerNet WWW redistribution takes less than two hours with a minimum of manual work. For 26,000 requests of information from our service per month the average costs for the worldwide delivery of one document is about 19 cents.

  2. Site preference of ternary alloying additions to NiTi: Fe, Pt, Pd, Au, Al, Cu, Zr and Hf

    NASA Technical Reports Server (NTRS)

    Bozzolo, Guillermo; Noebe, Ronald D.; Mosca, Hugo O.

    2004-01-01

    Atomistic modeling of the site substitution behavior of Pd in NiTi (J. Alloys and Comp. (2004), in press) has been extended to examine the behavior of several other alloying additions, namely, Fe, Pt, Au, Al, Cu, Zr and Hf in this important shape memory alloy. It was found that all elements, to a varying degree, displayed absolute preference for available sites in the deficient sublattice. How- ever, the energetics of the different substitutional schemes, coupled with large scale simulations indicate that the general trend in all cases is for the ternary addition to want to form stronger ordered structures with Ti.

  3. Reading level of privacy policies on Internet health Web sites.

    PubMed

    Graber, Mark A; D'Alessandro, Donna M; Johnson-West, Jill

    2002-07-01

    Most individuals would like to maintain the privacy of their medical information on the World Wide Web (WWW). In response, commercial interests and other sites post privacy policies that are designed to inform users of how their information will be used. However, it is not known if these statements are comprehensible to most WWW users. The purpose of this study was to determine the reading level of privacy statements on Internet health Web sites and to determine whether these statements can inform users of their rights. This was a descriptive study. Eighty Internet health sites were examined and the readability of their privacy policies was determined. The selected sample included the top 25 Internet health sites as well as other sites that a user might encounter while researching a common problem such as high blood pressure. Sixty percent of the sites were commercial (.com), 17.5% were organizations (.org), 8.8% were from the United Kingdom (.uk), 3.8% were United States governmental (.gov), and 2.5% were educational (.edu). The readability level of the privacy policies was calculated using the Flesch, the Fry, and the SMOG readability levels. Of the 80 Internet health Web sites studied, 30% (including 23% of the commercial Web sites) had no privacy policy posted. The average readability level of the remaining sites required 2 years of college level education to comprehend, and no Web site had a privacy policy that was comprehensible by most English-speaking individuals in the United States. The privacy policies of health Web sites are not easily understood by most individuals in the United States and do not serve to inform users of their rights. Possible remedies include rewriting policies to make them comprehensible and protecting online health information by using legal statutes or standardized insignias indicating compliance with a set of privacy standards (eg, "Health on the Net" [HON] http://www.hon.ch).

  4. Commercial WWW Site Appeal: How Does It Affect Online Food and Drink Consumers' Purchasing Behavior?

    ERIC Educational Resources Information Center

    White, Gregory K.; Manning, Barbara J.

    1998-01-01

    Reports on an online survey of consumer attitudes toward online storefronts marketing barbecue sauce, cheese, olive oil, potato chips, and other specialty food products. The relationship between consumer attitudes toward Web sites and the likelihood of purchase, as well as demographic factors related to online food and drink buying, are described.…

  5. A WWW-Based Archive and Retrieval System for Multimedia

    NASA Technical Reports Server (NTRS)

    Hyon, J.; Sorensen, S.; Martin, M.; Kawasaki, K.; Takacs, M.

    1996-01-01

    This paper describes the Data Distribution Laboratory (DDL) and discusses issues involved in building multimedia CD-ROMs. It describes the modeling philosophy for cataloging multimedia products and the worldwide-web (WWW)-based multimedia archive and retrieval system (Webcat) built on that model.

  6. A World Wide Web (WWW) server database engine for an organelle database, MitoDat.

    PubMed

    Lemkin, P F; Chipperfield, M; Merril, C; Zullo, S

    1996-03-01

    We describe a simple database search engine "dbEngine" which may be used to quickly create a searchable database on a World Wide Web (WWW) server. Data may be prepared from spreadsheet programs (such as Excel, etc.) or from tables exported from relationship database systems. This Common Gateway Interface (CGI-BIN) program is used with a WWW server such as available commercially, or from National Center for Supercomputer Algorithms (NCSA) or CERN. Its capabilities include: (i) searching records by combinations of terms connected with ANDs or ORs; (ii) returning search results as hypertext links to other WWW database servers; (iii) mapping lists of literature reference identifiers to the full references; (iv) creating bidirectional hypertext links between pictures and the database. DbEngine has been used to support the MitoDat database (Mendelian and non-Mendelian inheritance associated with the Mitochondrion) on the WWW.

  7. Never Too Young to Learn: Web Site Evaluation Is Elementary!

    ERIC Educational Resources Information Center

    Franklin, Lori L.

    2006-01-01

    This article is based on a series of lessons prepared for a class of third graders who were going to research specific planets. With so many Web sites on the Internet, there is a need to be concerned about information overload for the audience. The NASA site (www.nasa.gov) is filled with lots of sites providing factual information about the…

  8. A Framework for WWW Query Processing

    NASA Technical Reports Server (NTRS)

    Wu, Binghui Helen; Wharton, Stephen (Technical Monitor)

    2000-01-01

    Query processing is the most common operation in a DBMS. Sophisticated query processing has been mainly targeted at a single enterprise environment providing centralized control over data and metadata. Submitting queries by anonymous users on the web is different in such a way that load balancing or DBMS' accessing control becomes the key issue. This paper provides a solution by introducing a framework for WWW query processing. The success of this framework lies in the utilization of query optimization techniques and the ontological approach. This methodology has proved to be cost effective at the NASA Goddard Space Flight Center Distributed Active Archive Center (GDAAC).

  9. 78 FR 729 - Leonard Chemical Superfund Site; Catawba, York County, SC; Notice of Settlement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-04

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9767-7; CERCLA-04-2013-3752] Leonard Chemical Superfund Site... perform a Remedial Action at the Leonard Chemical Superfund Site located in Catawba, York County, South.... Submit your comments by Site name Leonard Chemical Superfund Site by one of the following methods: www...

  10. Carbonylation of Mitochondrial Aconitase with 4-Hydroxy-2-(E)-nonenal: Localization and Relative Reactivity of Addition Sites

    PubMed Central

    Liu, Qingyuan; Simpson, David C.; Gronert, Scott

    2013-01-01

    Mass spectrometry was used to investigate the effects of exposing mitochondrial aconitase (ACO2) to the membrane lipid peroxidation product, 4-hydroxy-2-(E)-nonenal (HNE). ACO2 was selected for this study because (1) it is known to be inactivated by HNE, (2) elevated concentrations of HNE-adducted ACO2 have been associated with disease states, (3) extensive structural information is available, and (4) the iron-sulfur cluster in ACO2 offers a critical target for HNE adduction. The aim of this study was to relate the inactivation of ACO2 by HNE to structural features. Initially, western blotting and an enzyme activity assay were used to assess aggregate effects and then gel electrophoresis, in-gel digestion, and tandem mass spectrometry were used to identify HNE addition sites. HNE addition reaction rates were determined for the most significant sites using the iTRAQ approach. The most reactive sites were Cys358, Cys421, and Cys424, the three iron-sulfur cluster-coordinating cysteines, Cys99, the closest non-ligated cysteine to the cluster, and Cys565, which is located in the cleft leading to the active site. Interestingly, both enzyme activity assay and iTRAQ relative abundance plots appeared to be trending toward horizontal asymptotes, rather than completion. PMID:23518448

  11. Web-phreeq: a WWW instructional tool for modeling the distribution of chemical species in water

    NASA Astrophysics Data System (ADS)

    Saini-Eidukat, Bernhardt; Yahin, Andrew

    1999-05-01

    A WWW-based tool, WEB-PHREEQ, was developed for classroom teaching and for routine calculation of low temperature aqueous speciation. Accessible with any computer that has an internet-connected forms-capable WWW-browser, WEB-PHREEQ provides user interface and other support for modeling, creates a properly formatted input file, passes it to the public domain program PHREEQC and returns the output to the WWW browser. Users can calculate the equilibrium speciation of a solution over a range of temperatures or can react solid minerals or gases with a particular water and examine the resulting chemistry. WEB-PHREEQ is one of a number of interactive distributed-computing programs available on the WWW that are of interest to geoscientists.

  12. 75 FR 27118 - Additional Designations, Foreign Narcotics Kingpin Designation Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-13

    ... OFAC's Web site ( http://www.treas.gov/ofac ) or via facsimile through a 24-hour fax-on demand service... establishes a program targeting the activities of significant foreign narcotics traffickers and their organizations on a worldwide basis. It provides a statutory framework for the President to impose sanctions...

  13. Heavy metal interaction for Andropogon scoparius and Rudbeckia hirta grown on soil from urban and rural sites with heavy metals additions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miles, L.J.; Parker, G.R.

    1979-10-01

    Little bluestem (Andropogon scoparius) and black-eyed Susan (Rudbeckia hirta) were grown in two soils with all combinations of Cd, Zn, Pb, and Cu at two levels each for 12 weeks. Germination and establishment were completely retarded by the addition of 1000 ..mu..g/g Zn as ZnCl/sub 2/, which was due to a salt effect. Neither Cd nor Cu additions affected germination. A slight decrease in germination was noted for Pb additions of 900 ..mu..g/g which may also be associated with a salt effect. Cadmium at 10- and 20-..mu..g/g addition rates did not affect top or root dry weight. Lead and Cumore » additions reduced shoot and root dry weight yields of Andropogon scoparius, root weights being more severely affected than shoot weights. Metal additions to the urban site soil did not reduce yields to the extent they did on the rural site soil. However, yields on the urban site soil control treatment were lower compared to those for the rural site control treatment. DTPA extraction levels of heavy metals were not well correlated to plant concentrations for comparisons between the two soils. It was concluded that DTPA soil extraction may not be acceptable for metal availability comparisons among soils of differing pH. Circumstantial evidence was found for both synergistic and antagonistic effects among the heavy metals. These were of a low level and no consistent response could be determined over species or soils.« less

  14. 75 FR 22391 - Notice of Web Site Publication for the Climate Program Office

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ...-01] Notice of Web Site Publication for the Climate Program Office AGENCY: Climate Program Office (CPO... its Web site at http://www.climate.noaa.gov . FOR FURTHER INFORMATION CONTACT: Eric Locklear; Chief... information is available on the Climate Program Office Web site pertaining to the CPO's research strategies...

  15. WWW Entrez: A Hypertext Retrieval Tool for Molecular Biology.

    ERIC Educational Resources Information Center

    Epstein, Jonathan A.; Kans, Jonathan A.; Schuler, Gregory D.

    This article describes the World Wide Web (WWW) Entrez server which is based upon the National Center for Biotechnology Information's (NCBI) Entrez retrieval database and software. Entrez is a molecular sequence retrieval system that contains an integrated view of portions of Medline and all publicly available nucleotide and protein databases,…

  16. Breeding site selection by coho salmon (Oncorhynchus kisutch) in relation to large wood additions and factors that influence reproductive success

    USGS Publications Warehouse

    Clark, Steven M.; Dunham, Jason B.; McEnroe, Jeffery R.; Lightcap, Scott W.

    2014-01-01

    The fitness of female Pacific salmon (Oncorhynchus spp.) with respect to breeding behavior can be partitioned into at least four fitness components: survival to reproduction, competition for breeding sites, success of egg incubation, and suitability of the local environment near breeding sites for early rearing of juveniles. We evaluated the relative influences of habitat features linked to these fitness components with respect to selection of breeding sites by coho salmon (Oncorhynchus kisutch). We also evaluated associations between breeding site selection and additions of large wood, as the latter were introduced into the study system as a means of restoring habitat conditions to benefit coho salmon. We used a model selection approach to organize specific habitat features into groupings reflecting fitness components and influences of large wood. Results of this work suggest that female coho salmon likely select breeding sites based on a wide range of habitat features linked to all four hypothesized fitness components. More specifically, model parameter estimates indicated that breeding site selection was most strongly influenced by proximity to pool-tail crests and deeper water (mean and maximum depths). Linkages between large wood and breeding site selection were less clear. Overall, our findings suggest that breeding site selection by coho salmon is influenced by a suite of fitness components in addition to the egg incubation environment, which has been the emphasis of much work in the past.

  17. Using Ambient Noise for Investigating Cultural Heritage Sites and Evaluating Seismic Site Response

    NASA Astrophysics Data System (ADS)

    D'Amico, S.; Farrugia, D.; Galea, P. M.; Ruben, B. P., Sr.

    2016-12-01

    Recordings of ambient noise as well as use of the HVSR technique represent a common tool for evaluating seismic site response. In this study we applied such techniques to several cultural heritage sites located on the Maltese archipelago (Central Mediterranean). In particular, two of the Maltese watchtowers, built by the Knights of St. John between 1637 and 1659, were investigated together with the megalithic temple site of Mnajdra. Array data were acquired using the Micromed SoilSpy Rosina™ equipped with 4.5 Hz vertical geophones, setting the array in an L-shaped configuration. The Extended Spatial Autocorrelation (ESAC) technique was used to extract Rayleigh-wave dispersion curves. Moreover, single-station data close to the array was collected using a Tromino 3-component seismograph (www.tromino.eu), and the H/V curves were extracted. The dispersion curves and the H/V curves were jointly inverted using the Genetic Algorithm (GA) to obtain the shear-wave velocity profile. A fixed number of layers was used in the inversion and ranges for the layer thickness, P-wave and S-wave velocity, and density were specified. The obtained velocity profiles were used to compute the amplification function for the site based on the square root of the effective seismic impedance, also known as the quarter-wavelength approximation. This was used in the simulation of ground motion parameters at the site for various earthquakes using the stochastic one-dimensional site response analysis algorithm, Extended Source Simulation (EXSIM). In addition, the fundamental period and the damping ratio of the watchtowers was obtained by recording ambient vibrations. In the megalithic temples we were also able to evaluate the coverage of the soil deposits within the structure, comparing our results with previous study that used different geophysical techniques. In conclusion, this study enables us to map the seismic amplification hazard and provides primary data on the seismic risk assessment of

  18. 78 FR 729 - Ellman Battery Superfund Site; Orlando, Orange County, FL; Notice of Settlement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-04

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9767-6; CERCLA-04-2012-3780] Ellman Battery Superfund Site... Action at the Ellman Battery Superfund Site located in Orlando, Orange County, Florida. DATES: The Agency... name Ellman Battery Superfund Site by one of the following methods: www.epa.gov/region4/superfund...

  19. 78 FR 13339 - Florida Petroleum Reprocessors Site; Davie, Broward County, FL; Notice of Settlement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-27

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL 9785-7; CERCLA-04-2013-3755] Florida Petroleum Reprocessors... settlement with 2238 NW. 86th Street Inc. concerning the Florida Petroleum Reprocessors Site located in Davie... by Site name Florida Petroleum Reprocesssors Site by one of the following methods: www.epa.gov...

  20. Nurses in need of additional support: web sites offering information in eldercare nursing environments.

    PubMed

    Matusitz, Jonathan; Breen, Gerald-Mark; Marathe, Shriram S; Wan, Thomas T H

    2010-01-01

    Studies have shown the usefulness of telemedicine and telecare in multiple settings. One form of telemedicine is e-health. Residents of nursing homes are a unique population that may significantly benefit from the e-health resources available to their caregivers. E-health Web sites appear to be viable, feasible, and timely interventional methods to provide the additional knowledge and support practitioners in these settings may need to provide preventative, reactive, and remedial care for frail residents.

  1. The WWW Cabinet of Curiosities: A Serendipitous Research Tool

    ERIC Educational Resources Information Center

    Arnold, Josie

    2012-01-01

    This paper proposes that the WWW is able to be fruitfully understood as a research tool when we utilise the metaphor of the cabinet of curiosities, the wunderkammer. It unpeels some of the research attributes of the metaphor as it reveals the multiplicity of connectivity on the web that provides serendipitous interactions between unexpected…

  2. An additional substrate binding site in a bacterial phenylalanine hydroxylase

    PubMed Central

    Ronau, Judith A.; Paul, Lake N.; Fuchs, Julian E.; Corn, Isaac R.; Wagner, Kyle T.; Liedl, Klaus R.; Abu-Omar, Mahdi M.; Das, Chittaranjan

    2014-01-01

    Phenylalanine hydroxylase (PAH) is a non-heme iron enzyme that catalyzes phenylalanine oxidation to tyrosine, a reaction that must be kept under tight regulatory control. Mammalian PAH features a regulatory domain where binding of the substrate leads to allosteric activation of the enzyme. However, existence of PAH regulation in evolutionarily distant organisms, such as certain bacteria in which it occurs, has so far been underappreciated. In an attempt to crystallographically characterize substrate binding by PAH from Chromobacterium violaceum (cPAH), a single-domain monomeric enzyme, electron density for phenylalanine was observed at a distal site, 15.7Å from the active site. Isothermal titration calorimetry (ITC) experiments revealed a dissociation constant of 24 ± 1.1 µM for phenylalanine. Under the same conditions, no detectable binding was observed in ITC for alanine, tyrosine, or isoleucine, indicating the distal site may be selective for phenylalanine. Point mutations of residues in the distal site that contact phenylalanine (F258A, Y155A, T254A) lead to impaired binding, consistent with the presence of distal site binding in solution. Kinetic analysis reveals that the distal site mutants suffer a discernible loss in their catalytic activity. However, x-ray structures of Y155A and F258A, two of the mutants showing more noticeable defect in their activity, show no discernible change in their active site structure, suggesting that the effect of distal binding may transpire through protein dynamics in solution. PMID:23860686

  3. Biodegradation of diesel by mixed bacteria immobilized onto a hybrid support of peat moss and additives: a batch experiment.

    PubMed

    Lee, Young-Chul; Shin, Hyun-Jae; Ahn, Yeonghee; Shin, Min-Chul; Lee, Myungjin; Yang, Ji-Won

    2010-11-15

    We report microbial cell immobilization onto a hybrid support of peat moss for diesel biodegradation. Three strains isolated from a site contaminated with diesel oil were used in this study: Acinetobacter sp., Gordonia sp., and Rhodococcus sp. To increase not only diesel adsorption but also diesel biodegradation, additives such as zeolite, bentonite, chitosan, and alginate were tested. In this study, a peat moss, bentonite, and alginate (2/2.9/0.1 g, w/w/w) hybrid support (PBA) was the best support matrix, considering both diesel physical adsorption capacity and mixed microbial immobilization. Copyright © 2010 Elsevier B.V. All rights reserved.

  4. 31 CFR Appendix A to Part 560 - Persons Determined To Be the Government of Iran, as Defined in § 560.304 of This Part

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... through the following page on OFAC's Web site: http://www.treasury.gov/sdn. Additional information.... This document and additional information concerning OFAC are available from OFAC's Web site: http://www... via facsimile through a 24-hour fax-on-demand service, tel.: 202/622-0077. Please consult OFAC's Web...

  5. 76 FR 47391 - Mandatory Reporting of Greenhouse Gases

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    ...://www.regulations.gov Web site is an ``anonymous access'' system, which means EPA will not know your... Rule Program Web site http://www.epa.gov/climatechange/emissions/ghgrulemaking.html . To submit a.../ghgrulemaking.html . Alternatively, contact Carole Cook at 202-343-9263. Worldwide Web (WWW). In addition to...

  6. Nevada National Security Site Environmental Report 2011

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cathy Wills, ed

    2012-09-12

    This report was prepared to meet the information needs of the public and the requirements and guidelines of the U.S. Department of Energy (DOE) for annual site environmental reports. It was prepared by National Security Technologies, LLC (NSTec), for the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO). This and previous years reports, called Annual Site Environmental Reports (ASERs), Nevada Test Site Environmental Reports (NTSERs), and, beginning in 2010, Nevada National Security Site Environmental Reports (NNSSERs), are posted on the NNSA/NSO website at http://www.nv.energy.gov/library/publications/aser.aspx. This NNSSER was prepared to satisfy DOE Order DOE O 231.1B, 'Environment,more » Safety and Health Reporting.' Its purpose is to (1) report compliance status with environmental standards and requirements, (2) present results of environmental monitoring of radiological and nonradiological effluents, (3) report estimated radiological doses to the public from releases of radioactive material, (4) summarize environmental incidents of noncompliance and actions taken in response to them, (5) describe the NNSA/NSO Environmental Management System and characterize its performance, and (6) highlight significant environmental programs and efforts. This NNSSER summarizes data and compliance status for calendar year 2011 at the Nevada National Security Site (NNSS) (formerly the Nevada Test Site) and its two support facilities, the North Las Vegas Facility (NLVF) and the Remote Sensing Laboratory-Nellis (RSL-Nellis). It also addresses environmental restoration (ER) projects conducted at the Tonopah Test Range (TTR). Through a Memorandum of Agreement, NNSA/NSO is responsible for the oversight of TTR ER projects, and the Sandia Site Office of NNSA (NNSA/SSO) has oversight of all other TTR activities. NNSA/SSO produces the TTR annual environmental report available at http://www.sandia.gov/news/publications/environmental/index.html.« less

  7. 77 FR 11533 - Anniston PCB Superfund Site, Anniston, Calhoun County, Alabama; Notice of Amended Settlement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-27

    ... ENVIRONMENTAL PROTECTION AGENCY [CERCLA-04-2012-3763; FRL 9637-7] Anniston PCB Superfund Site... past response costs concerning the Anniston PCB Superfund Site located in Anniston, Calhoun County.... Submit your comments by Site name Anniston PCB by one of the following methods: www.epa.gov/region4...

  8. Test-retest and between-site reliability in a multicenter fMRI study.

    PubMed

    Friedman, Lee; Stern, Hal; Brown, Gregory G; Mathalon, Daniel H; Turner, Jessica; Glover, Gary H; Gollub, Randy L; Lauriello, John; Lim, Kelvin O; Cannon, Tyrone; Greve, Douglas N; Bockholt, Henry Jeremy; Belger, Aysenil; Mueller, Bryon; Doty, Michael J; He, Jianchun; Wells, William; Smyth, Padhraic; Pieper, Steve; Kim, Seyoung; Kubicki, Marek; Vangel, Mark; Potkin, Steven G

    2008-08-01

    In the present report, estimates of test-retest and between-site reliability of fMRI assessments were produced in the context of a multicenter fMRI reliability study (FBIRN Phase 1, www.nbirn.net). Five subjects were scanned on 10 MRI scanners on two occasions. The fMRI task was a simple block design sensorimotor task. The impulse response functions to the stimulation block were derived using an FIR-deconvolution analysis with FMRISTAT. Six functionally-derived ROIs covering the visual, auditory and motor cortices, created from a prior analysis, were used. Two dependent variables were compared: percent signal change and contrast-to-noise-ratio. Reliability was assessed with intraclass correlation coefficients derived from a variance components analysis. Test-retest reliability was high, but initially, between-site reliability was low, indicating a strong contribution from site and site-by-subject variance. However, a number of factors that can markedly improve between-site reliability were uncovered, including increasing the size of the ROIs, adjusting for smoothness differences, and inclusion of additional runs. By employing multiple steps, between-site reliability for 3T scanners was increased by 123%. Dropping one site at a time and assessing reliability can be a useful method of assessing the sensitivity of the results to particular sites. These findings should provide guidance toothers on the best practices for future multicenter studies.

  9. Identification of Bacteria Synthesizing Ribosomal RNA in Response to Uranium Addition During Biostimulation at the Rifle, CO Integrated Field Research Site

    PubMed Central

    McGuinness, Lora R.; Wilkins, Michael J.; Williams, Kenneth H.; Long, Philip E.; Kerkhof, Lee J.

    2015-01-01

    Understanding which organisms are capable of reducing uranium at historically contaminated sites provides crucial information needed to evaluate treatment options and outcomes. One approach is determination of the bacteria which directly respond to uranium addition. In this study, uranium amendments were made to groundwater samples from a site of ongoing biostimulation with acetate. The active microbes in the planktonic phase were deduced by monitoring ribosomes production via RT-PCR. The results indicated several microorganisms were synthesizing ribosomes in proportion with uranium amendment up to 2 μM. Concentrations of U (VI) >2 μM were generally found to inhibit ribosome synthesis. Two active bacteria responding to uranium addition in the field were close relatives of Desulfobacter postgateii and Geobacter bemidjiensis. Since RNA content often increases with growth rate, our findings suggest it is possible to rapidly elucidate active bacteria responding to the addition of uranium in field samples and provides a more targeted approach to stimulate specific populations to enhance radionuclide reduction in contaminated sites. PMID:26382047

  10. Nevada Test Site Environmental Report 2009

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cathy Wills, ed.

    2010-09-13

    The Nevada Test Site Environmental Report 2009 was prepared to meet the information needs of the public and the requirements and guidelines of the U.S. Department of Energy (DOE) for annual site environmental reports. It was prepared by National Security Technologies, LLC (NSTec), for the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office (NNSA/NSO). This and previous years’ Nevada Test Site Environmental Reports (NTSERs) are posted on the NNSA/NSO website at http://www.nv.doe.gov/library/publications/aser.aspx. This NTSER was prepared to satisfy DOE Order DOE O 231.1A, “Environment, Safety and Health Reporting.” Its purpose is to (1) report compliance status withmore » environmental standards and requirements, (2) present results of environmental monitoring of radiological and nonradiological effluents, (3) report estimated radiological doses to the public from releases of radioactive material, (4) summarize environmental incidents of noncompliance and actions taken in response to them, (5) describe the NNSA/NSO Environmental Management System and characterize its performance, and (6) highlight significant environmental programs and efforts. This NTSER summarizes data and compliance status for calendar year 2009 at the Nevada Test Site (NTS) and its two support facilities, the North Las Vegas Facility (NLVF) and the Remote Sensing Laboratory (RSL)-Nellis. It also addresses environmental restoration (ER) projects conducted at the Tonopah Test Range (TTR). Through a Memorandum of Agreement, NNSA/NSO is responsible for the oversight of TTR ER projects, and the Sandia Site Office of NNSA (NNSA/SSO) has oversight of all other TTR activities. NNSA/SSO produces the TTR annual environmental report available at http://www.sandia.gov/news/publications/environmental/index.html.« less

  11. [Learning from regional differences: online platform: http://www.versorgungsatlas.de].

    PubMed

    Mangiapane, S

    2014-02-01

    In 2011, the Central Research Institute of Ambulatory Health Care in Germany (ZI) published the website http://www.versorgungsatlas.de, a portal that presents research results from regional health services in Germany. The Web portal provides a publicly accessible source of information and a growing number of selected analyses focusing on regional variation in health care. Each topic is presented in terms of interactive maps, tables, and diagrams and is supplemented by a paper that examines the results in detail and provides an explanation of the findings. The portal has been designed to provide a forum on which health service researchers can publish their results derived from various data sources of different institutions in Germany and can comment on results already available on http://www.versorgungsatlas.de. For health policy actors, the discussion of regional differences offers a new, previously unavailable basis for determining the region-specific treatment needs and for providing health-care management with the goal of high-quality care for each resident.

  12. 76 FR 38389 - Caraleigh Phosphate and Fertlizer Works Superfund Site; Raleigh, Wake County, NC; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-30

    ... and Fertlizer Works Superfund Site; Raleigh, Wake County, NC; Notice of Settlement AGENCY... Caraleigh Phosphate and Fertilizer Works Superfund Site located in Raleigh, Wake County, North Carolina for... Phosphate and Fertilizer Works Superfund Site by one of the following methods: http://www.regulations.gov...

  13. Web site access statistics and delivery of research results

    Treesearch

    Daniel L. Schmoldt; Matthew F. Winn; Philip A. Araman

    1998-01-01

    For the past 2-1/2 years, our Research Work Unit (RWU) has been operating a Web site (http://www.se4702.forprod.vt.edu). The site became operational in October 1995. In the beginning, it was primarily designed to stake out a piece of the Internet with our name and our RWU’s organizational mission. Quickly, it became apparent to us, however, that our user community...

  14. Web site review. Carolinas HealthCare recognized Internet marketing potential early.

    PubMed

    Botvin, Judith D

    2005-01-01

    Since the early days of the Internet, administrators Carolinas HealthCare System in Charlotte, NC, have appreciated its potential as a marketing tool. This places a lot of expectations on the Web site, www.carolinashealthcare.org, which is managed by the marketing-public relations department. Find out how the well-established site fulfills its mission and more.

  15. POOL server: machine learning application for functional site prediction in proteins.

    PubMed

    Somarowthu, Srinivas; Ondrechen, Mary Jo

    2012-08-01

    We present an automated web server for partial order optimum likelihood (POOL), a machine learning application that combines computed electrostatic and geometric information for high-performance prediction of catalytic residues from 3D structures. Input features consist of THEMATICS electrostatics data and pocket information from ConCavity. THEMATICS measures deviation from typical, sigmoidal titration behavior to identify functionally important residues and ConCavity identifies binding pockets by analyzing the surface geometry of protein structures. Both THEMATICS and ConCavity (structure only) do not require the query protein to have any sequence or structure similarity to other proteins. Hence, POOL is applicable to proteins with novel folds and engineered proteins. As an additional option for cases where sequence homologues are available, users can include evolutionary information from INTREPID for enhanced accuracy in site prediction. The web site is free and open to all users with no login requirements at http://www.pool.neu.edu. m.ondrechen@neu.edu Supplementary data are available at Bioinformatics online.

  16. Ocean Drilling Program: Web Site Access Statistics

    Science.gov Websites

    and products Drilling services and tools Online Janus database Search the ODP/TAMU web site ODP's main See statistics for JOIDES members. See statistics for Janus database. 1997 October November December accessible only on www-odp.tamu.edu. ** End of ODP, start of IODP. Privacy Policy ODP | Search | Database

  17. 76 FR 44912 - Callaway and Son Drum Service Superfund Site; Lake Alfred, Polk County, FL; Notice of Settlement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-27

    ... Service Superfund Site; Lake Alfred, Polk County, FL; Notice of Settlement AGENCY: Environmental... Callaway and son Drum Service Superfund Site located in Lake Alfred, Polk County, Florida for publication... by Site name Callaway and Son Drum Service Superfund Site by one of the following methods: http://www...

  18. 75 FR 70956 - Post Office Closing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    ... electronically via the Commission's Filing Online system at http:[sol][sol]www.prc.gov. Those who cannot submit... supporting material on its Web site at http:[sol][sol]www.prc.gov. Additional filings in this case and...) pursuant to Commission rules 9(a) and 10(a) at the Commission's Web site, http:[sol][sol]www.prc.gov...

  19. Identification of bacteria synthesizing ribosomal RNA in response to uranium addition during biostimulation at the Rifle, CO Integrated Field Research site

    DOE PAGES

    McGuinness, Lora R.; Wilkins, Michael J.; Williams, Kenneth H.; ...

    2015-09-18

    Understanding which organisms are capable of reducing uranium at historically contaminated sites provides crucial information needed to evaluate treatment options and outcomes. One approach is determination of the bacteria which directly respond to uranium addition. In this research, uranium amendments were made to groundwater samples from a site of ongoing biostimulation with acetate. The active microbes in the planktonic phase were deduced by monitoring ribosomes production via RT-PCR. The results indicated several microorganisms were synthesizing ribosomes in proportion with uranium amendment up to 2 μM. Concentrations of U (VI) >2 μM were generally found to inhibit ribosome synthesis. Two activemore » bacteria responding to uranium addition in the field were close relatives of Desulfobacter postgateii and Geobacter bemidjiensis. Since RNA content often increases with growth rate, our findings suggest it is possible to rapidly elucidate active bacteria responding to the addition of uranium in field samples and provides a more targeted approach to stimulate specific populations to enhance radionuclide reduction in contaminated sites.« less

  20. [Development of laboratory sequence analysis software based on WWW and UNIX].

    PubMed

    Huang, Y; Gu, J R

    2001-01-01

    Sequence analysis tools based on WWW and UNIX were developed in our laboratory to meet the needs of molecular genetics research in our laboratory. General principles of computer analysis of DNA and protein sequences were also briefly discussed in this paper.

  1. Effectiveness of the addition of alkaline materials at surface coal mines in preventing or abating acid mine drainage--Part 2. Mine site case studies

    USGS Publications Warehouse

    Brady, Keith; Smith, Michael W.; Beam, Richard L.; Cravotta,, Charles A.

    1990-01-01

    The effectiveness of preventing or ameliorating acid mine drainage (AMD) through the application of alkaline additives is evaluated for eight surface coal mines in Pennsylvania. Many of the mine sites had overburden characteristics that made prediction of post‐mining water quality uncertain. Alkaline materials were applied at rates ranging from 42 to greater than 1,000 tons as calcium carbonate per acre. In addition, two sites that were mined and reclaimed without alkaline additives are included for comparative purposes. Overburden sulfur concentration and "neutralization potential" (NP) data for multiple strata at each mine site were used to compute the cumulative, mass‐weighted "maximum potential acidity" (MPA) and "net neutralization potential" (NNP = NP ‐ MPA) by using three different calculation methods. Post‐reclamation water‐quality data were used to compute the net alkalinity (= alkalinity ‐ acidity). The most conservative determination of NNP, whereby MPA is calculated by multiplying the total sulfur concentration, in weight percent, by 62.5 instead of 31.25, yielded the best agreement with net alkalinity (patching signs on NNP and net alkalinity). The error in prediction using each method was that the reclaimed overburden was computed to be alkaline overall (NNP > 0), but the post‐reclamation water was acid (net alkalinity < 0). In general, alkaline addition rates were probably insufficient to neutralize, or too late to prevent, acid production in the mine spoil. At six of the seven mine sites that had overburden with insufficient NP relative to MPA (NNP < 0), the addition of alkaline materials failed to create alkaline mine drainage; AMD was formed or persisted. A control site which also had insufficient alkaline material, but did not incorporate alkaline additives, generated severe AMD. Two sites that had substantial, natural alkaline overburden produced alkaline drainage. Although the addition rates appear to be inadequate, other factors

  2. MX Siting Investigation. Mineral Resources Survey, Seven Additional Valleys, Nevada/Utah Siting Area. Volume I.

    DTIC Science & Technology

    1981-06-23

    Some negative impacts of MX deployment on mining in the study area are unavoidable, but careful planning in water use and actual shelter site...depend upon the extent of deployment and location of shelter sites. A major impact on the mining industry will result if draw-down of the water table...use and acquire the necessary land rights or whether the affected shelter (s) should be abandoned or replaced elsewhere in the deployment area. Egec E-TR

  3. Highly Interactive WWW Services: A New Type of Information Sources.

    ERIC Educational Resources Information Center

    Vanouplines, Patrick; Nieuwenhuysen, P.

    The World Wide Web is evolving from a collection of texts linked by hypertext and hypermedia toward services that operate interactively with the information user, and which offer results through use of a broad spectrum of tools. This paper presents a collection of interactive WWW services. The services are classified on the basis of the client…

  4. An introduction to the special issue on ecological sites

    USDA-ARS?s Scientific Manuscript database

    The establishment of the Rangeland Interagency Ecological Site Manual by the Natural Resources Conservation Service (NRCS), Forest Service (FS), and the Bureau of Land Management (BLM) heralds a new era of rangeland management in the United States (http://www.fs.fed.us/biology/soil/Signed_RIESM_2010...

  5. Nevada National Security Site Environmental Report 2013

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wills, C.

    2014-09-09

    This report was prepared to meet the information needs of the public and the requirements and guidelines of the U.S. Department of Energy (DOE) for annual site environmental reports. It was prepared by National Security Technologies, LLC (NSTec), for the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office (NNSA/NFO) (formerly designated as the Nevada Site Office [NNSA/NSO]). The new field office designation occurred in March 2013. Published reports cited in this 2013 report, therefore, may bear the name or authorship of NNSA/NSO. This and previous years’ reports, called Annual Site Environmental Reports (ASERs), Nevada Test Site Environmentalmore » Reports (NTSERs), and, beginning in 2010, Nevada National Security Site Environmental Reports (NNSSERs), are posted on the NNSA/NFO website at http://www.nv.energy.gov/library/publications/aser.aspx.« less

  6. FOCUSED FEASIBILITY STUDY OF PHYTOREMEDIATION ALTERNATIVE FOR THE INDUSTRIAL EXCESS LANDFILL SITE IN STARK COUNTY, OHIO.

    EPA Science Inventory

    Focused feasibility study of phytoremediation alternative for the Industrial Excess Landfill site in Stark County, Ohio. More information can be found on the NPL Fact Sheet for this site at www.epa.gov/region5/superfund/npl/ohio/OHD000377971.htm

  7. Remediation management of complex sites using an adaptive site management approach.

    PubMed

    Price, John; Spreng, Carl; Hawley, Elisabeth L; Deeb, Rula

    2017-12-15

    Complex sites require a disproportionate amount of resources for environmental remediation and long timeframes to achieve remediation objectives, due to their complex geologic conditions, hydrogeologic conditions, geochemical conditions, contaminant-related conditions, large scale of contamination, and/or non-technical challenges. A recent team of state and federal environmental regulators, federal agency representatives, industry experts, community stakeholders, and academia worked together as an Interstate Technology & Regulatory Council (ITRC) team to compile resources and create new guidance on the remediation management of complex sites. This article summarizes the ITRC team's recommended process for addressing complex sites through an adaptive site management approach. The team provided guidance for site managers and other stakeholders to evaluate site complexities and determine site remediation potential, i.e., whether an adaptive site management approach is warranted. Adaptive site management was described as a comprehensive, flexible approach to iteratively evaluate and adjust the remedial strategy in response to remedy performance. Key aspects of adaptive site management were described, including tools for revising and updating the conceptual site model (CSM), the importance of setting interim objectives to define short-term milestones on the journey to achieving site objectives, establishing a performance model and metrics to evaluate progress towards meeting interim objectives, and comparing actual with predicted progress during scheduled periodic evaluations, and establishing decision criteria for when and how to adapt/modify/revise the remedial strategy in response to remedy performance. Key findings will be published in an ITRC Technical and Regulatory guidance document in 2017 and free training webinars will be conducted. More information is available at www.itrc-web.org. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. 77 FR 59878 - Additional Requirements for Charitable Hospitals; Hearing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ... public hearing is being held in the IRS Auditorium, Internal Revenue Service Building, 1111 Constitution... Constitution Avenue entrance. In addition, all visitors must present photo identification to enter the building... Constitution Avenue NW., Washington, DC or sent electronically via the Federal eRulemaking Portal at www...

  9. Data Validation Package, June 2016 Groundwater Sampling at the Hallam, Nebraska, Decommissioned Reactor Site, August 2016

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Surovchak, Scott; Miller, Michele

    The 2008 Long-Term Surveillance Plan [LTSP] for the Decommissioned Hallam Nuclear Power Facility, Hallam, Nebraska (http://www.lm.doe.gov/Hallam/Documents.aspx) requires groundwater monitoring once every 2 years. Seventeen monitoring wells at the Hallam site were sampled during this event as specified in the plan. Planned monitoring locations are shown in Attachment 1, Sampling and Analysis Work Order. Water levels were measured at all sampled wells and at two additional wells (6A and 6B) prior to the start of sampling. Additionally, water levels of each sampled well were measured at the beginning of sampling. See Attachment 2, Trip Report, for additional details. Sampling and analysismore » were conducted as specified in Sampling and Analysis Plan for U.S. Department of Energy Office of Legacy Management Sites (LMS/PRO/S04351, continually updated, http://energy.gov/lm/downloads/sampling-and-analysis-plan-us-department- energy-office-legacy-management-sites). Gross alpha and gross beta are the only parameters that were detected at statistically significant concentrations. Time/concentration graphs of the gross alpha and gross beta data are included in Attachment 3, Data Presentation. The gross alpha and gross beta activity concentrations observed are consistent with values previously observed and are attributed to naturally occurring radionuclides (e.g., uranium and uranium decay chain products) in the groundwater.« less

  10. Off-site Emergency Planning at UK Nuclear Licensed Sites.

    PubMed

    Leonard, Paul; Thomas, Gareth

    2017-04-01

    Nuclear emergency planning arrangements in the UK are continually kept under review. This work proposes to outline how experience from nuclear exercises and undertaking emergency response duties can be based on radiological knowledge of specific sites and utilised in the future. In 2014, the UK regulator, the Office for Nuclear Regulation (ONR) revised their principles for the determination of off-site emergency planning areas around nuclear sites where predetermined countermeasures and other protection measures are applied to protect those people who may be affected by a radiation emergency. The revised principles also enhanced communication from the nuclear site operators and local authorities to the public. This updated ONR's application of the UK Radiation (Emergency Preparedness and Public Information) Regulations 2001 (REPPIR) http://www.hse.gov.uk/radiation/ionising/reppir.htm, which includes details of minimising potential doses to the public, as well as assessment and reassurance, linked to other concurrent risks such as flooding. ONR undertakes site-specific assessments of each operators' hazard identification and risk evaluation, which include consideration of whether the public might receive a significant radiation dose in the year following the emergency (excluding countermeasures in the first 24 hours). In defining the areas for off-site emergency planning, practical and strategic factors are then considered, which include other local non-nuclear emergency planning arrangements and experience, and whether local geographic and demographic aspects could aid public credibility and confidence. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  11. Virtual dermatohistopathology at http://www.pathowiki.org.

    PubMed

    Roßner, Mathias; Roßner, Florian; Zwönitzer, Ralf; Hofmann, Harald; Sterry, Wolfram; Kalinski, Thomas

    2012-04-01

    PATHOWIKI (http://www.pathowiki.org) is a new specialized information system in the form of a web-based wiki with content from all sub-disciplines of human pathology. Essential components are articles and specimens which are located thematically in dermatopathology. The project is presented on the basis of impressive examples and possibilities. The ability to link all kinds of content and integrate pattern analysis theories creates an effective tool for teaching and training in dermatopathology. Collaborative work ensures the effective usage of available resources and a continually growing amount of content, the quality of which depends on the number of users and should be as high as possible. Therefore, all interested colleagues are invited to support the project. © The Authors • Journal compilation © Blackwell Verlag GmbH, Berlin.

  12. Asymmetric Iridium Catalyzed C-C Coupling of Chiral Diols via Site-Selective Redox-Triggered Carbonyl Addition

    PubMed Central

    Shin, Inji; Krische, Michael J.

    2015-01-01

    Cyclometalated π-allyliridium C,O-benzoate complexes modified by axially chiral chelating phosphine ligands display a pronounced kinetic preference for primary alcohol dehydrogenation, enabling highly site-selective redox-triggered carbonyl additions of chiral primary-secondary 1,3-diols with exceptional levels of catalyst-directed diastereoselectivity. Unlike conventional methods for carbonyl allylation, the present redox-triggered alcohol C-H functionalizations bypass the use of protecting groups, premetalated reagents, and discrete alcohol-to-aldehyde redox reactions. PMID:26187028

  13. Use of the WWW as a Collaborative Tool in a Large HEP Collaboration

    NASA Astrophysics Data System (ADS)

    Bower, G.; Dubois, R.; Johnson, A. S.; Moss, L.; Perl, J.; Langston, M.; Weiss, E.

    As the phenomenal growth of the WWW continues it is easy to view it purely as a tool for PR and advertising, and to forget its roots as a collaborative tool for HEP research. The SLD collaboration has made extensive use of WWW in this latter role, using it to allow collaborators to sign up for shifts, to monitor physics data-taking in near real time, and as a tool to educate and inform collaborators. By their nature such tools are accessible to all collaborators wherever they are located. In this talk we will describe our current system and comment on its effectiveness, and discuss possible enhancements based on forthcoming more powerful web browsers.

  14. Methanopyrus kandleri topoisomerase V contains three distinct AP lyase active sites in addition to the topoisomerase active site

    PubMed Central

    Rajan, Rakhi; Osterman, Amy; Mondragón, Alfonso

    2016-01-01

    Topoisomerase V (Topo-V) is the only topoisomerase with both topoisomerase and DNA repair activities. The topoisomerase activity is conferred by a small alpha-helical domain, whereas the AP lyase activity is found in a region formed by 12 tandem helix-hairpin-helix ((HhH)2) domains. Although it was known that Topo-V has multiple repair sites, only one had been mapped. Here, we show that Topo-V has three AP lyase sites. The atomic structure and Small Angle X-ray Scattering studies of a 97 kDa fragment spanning the topoisomerase and 10 (HhH)2 domains reveal that the (HhH)2 domains extend away from the topoisomerase domain. A combination of biochemical and structural observations allow the mapping of the second repair site to the junction of the 9th and 10th (HhH)2 domains. The second site is structurally similar to the first one and to the sites found in other AP lyases. The 3rd AP lyase site is located in the 12th (HhH)2 domain. The results show that Topo-V is an unusual protein: it is the only known protein with more than one (HhH)2 domain, the only known topoisomerase with dual activities and is also unique by having three AP lyase repair sites in the same polypeptide. PMID:26908655

  15. Improved Coast Guard Communications Using Commercial Satellites and WWW Technology: Slide Presentation

    DOT National Transportation Integrated Search

    1997-06-18

    The slides in this file amplify a paper that was presented at International Mobile Satellite Conference, (IMSC-97), Pasadena CA on 18 June 1997. The text of that presentation can be found at http://www.bts.gov/NTL/data/imsc.pdf.

  16. DeepSite: protein-binding site predictor using 3D-convolutional neural networks.

    PubMed

    Jiménez, J; Doerr, S; Martínez-Rosell, G; Rose, A S; De Fabritiis, G

    2017-10-01

    An important step in structure-based drug design consists in the prediction of druggable binding sites. Several algorithms for detecting binding cavities, those likely to bind to a small drug compound, have been developed over the years by clever exploitation of geometric, chemical and evolutionary features of the protein. Here we present a novel knowledge-based approach that uses state-of-the-art convolutional neural networks, where the algorithm is learned by examples. In total, 7622 proteins from the scPDB database of binding sites have been evaluated using both a distance and a volumetric overlap approach. Our machine-learning based method demonstrates superior performance to two other competitive algorithmic strategies. DeepSite is freely available at www.playmolecule.org. Users can submit either a PDB ID or PDB file for pocket detection to our NVIDIA GPU-equipped servers through a WebGL graphical interface. gianni.defabritiis@upf.edu. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  17. 31 CFR 380.5 - Where can I find current information, and who can I contact for additional guidance and...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... on Treasury's Bureau of the Public Debt Web site at http://www.treasurydirect.gov. You may also..., Bureau of the Public Debt, Office of the Commissioner, Government Securities Regulations Staff, 799 9th...

  18. 76 FR 40773 - Additional Designation of Entities Pursuant to Executive Order 13382 and Information Regarding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-11

    ... INVESTMENT COMPANY; a.k.a. MEHR IRANIAN ECONOMY COMPANY; a.k.a. MEHR IRANIAN ECONOMY INVESTMENTS; f.k.a... Square, Tehran, Iran; No. 48, 14th Alley, Ahmad Qassir Street, Argentina Square, Tehran, Iran; Business Registration Document 103222 (Iran); Web site http://www.mebank.ir ; Telephone: 982188526300; Alt. Telephone...

  19. PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

    PubMed Central

    Hornbeck, Peter V.; Zhang, Bin; Murray, Beth; Kornhauser, Jon M.; Latham, Vaughan; Skrzypek, Elzbieta

    2015-01-01

    PhosphoSitePlus® (PSP, http://www.phosphosite.org/), a knowledgebase dedicated to mammalian post-translational modifications (PTMs), contains over 330 000 non-redundant PTMs, including phospho, acetyl, ubiquityl and methyl groups. Over 95% of the sites are from mass spectrometry (MS) experiments. In order to improve data reliability, early MS data have been reanalyzed, applying a common standard of analysis across over 1 000 000 spectra. Site assignments with P > 0.05 were filtered out. Two new downloads are available from PSP. The ‘Regulatory sites’ dataset includes curated information about modification sites that regulate downstream cellular processes, molecular functions and protein-protein interactions. The ‘PTMVar’ dataset, an intersect of missense mutations and PTMs from PSP, identifies over 25 000 PTMVars (PTMs Impacted by Variants) that can rewire signaling pathways. The PTMVar data include missense mutations from UniPROTKB, TCGA and other sources that cause over 2000 diseases or syndromes (MIM) and polymorphisms, or are associated with hundreds of cancers. PTMVars include 18 548 phosphorlyation sites, 3412 ubiquitylation sites, 2316 acetylation sites, 685 methylation sites and 245 succinylation sites. PMID:25514926

  20. The NeMO Explorer Web Site: Interactive Exploration of a Recent Submarine Eruption and Hydrothermal Vents, Axial Volcano, Juan de Fuca Ridge

    NASA Astrophysics Data System (ADS)

    Weiland, C.; Chadwick, W. W.; Embley, R. W.

    2001-12-01

    To help visualize the submarine volcanic landscape at NOAA's New Millennium Observatory (NeMO), we have created the NeMO Explorer web site: http://www.pmel.noaa.gov/vents/nemo/explorer.html. This web site takes visitors a mile down beneath the ocean surface to explore Axial Seamount, an active submarine volcano 300 miles off the Oregon coast. We use virtual reality to put visitors in a photorealistic 3-D model of the seafloor that lets them view hydrothermal vents and fresh lava flows as if they were really on the seafloor. At each of six virtual sites there is an animated tour and a 360o panorama in which users can view the volcanic landscape and see biological communities within a spatially accurate context. From the six sites there are hyperlinks to 50 video clips taken by a remotely operated vehicle. Each virtual site concentrates on a different topic, including the dynamics of the 1998 eruption at Axial volcano (Rumbleometer), high-temperature hydrothermal vents (CASM and ASHES), diffuse hydrothermal venting (Marker33), subsurface microbial blooms (The Pit), and the boundary between old and new lavas (Castle vent). In addition to exploring the region geographically, visitors can also explore the web site via geological concepts. The concepts gallery lets you quickly find information about mid-ocean ridges, hydrothermal vents, vent fauna, lava morphology, and more. Of particular interest is an animation of the January 1998 eruption, which shows the rapid inflation (by over 3 m) and draining of the sheet flow. For more info see Fox et al., Nature, v.412, p.727, 2001. This project was funded by NOAA's High Performance Computing and Communication (HPCC) and Vents Programs. Our goal is to present a representative portion of the vast collection of NOAA's multimedia imagery to the public in a way that is easy to use and understand. These data are particularly challenging to present because of their high data rates and low contextual information. The 3-D models create

  1. 77 FR 46911 - Approval and Promulgation of Air Quality Implementation Plans; Michigan; Regional Haze State...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-06

    .... or until all parties present have had the opportunity to speak. EPA shall maintain a Web site at http... or otherwise protected through www.regulations.gov or email. The www.regulations.gov Web site is an... viruses. For additional instructions on submitting comments, go to Section I of the SUPPLEMENTARY...

  2. [Preparation of the database and the Internet (WWW) homepage for regulations on chemicals in Japan].

    PubMed

    Yamamoto, M; Morita, M; Kaminuma, T

    1999-01-01

    We prepared a database on chemical regulations in Japan. The regulations consist of "The Law concerning the Examination and Regulation of Manufacture, etc., of Chemical Substances", "Poisonous and Deleterious Substances", Control Law", "Waterworks Law", "Law for the Control of Household Products containing Harmful Substances", and Pesticide Residues in Food Sanitation Law". We also set up a World Wide Web (WWW) homepage containing an explanation of the law as well as chemical names, CAS registry numbers, and standards. The WWW pages contain lists of chemicals and the retrieval page for the database.

  3. Public outreach supports the entire life-cycle of the Ketzin pilot site, Germany

    NASA Astrophysics Data System (ADS)

    Martens, Sonja; Kollersberger, Tanja; Möller, Fabian; Liebscher, Axel

    2017-04-01

    Interdisciplinary research at the Ketzin pilot site in Germany contributes to the understanding of the geological CO2 storage since 2004. In addition to the research activities, public outreach has been a key element through the entire life-cycle of the project including site assessment, characterization, development as well as operation (2008-2013) and post-closure. From the very beginning of the project, the research activities were accompanied by an open dialogue with the general public including locals and interested people from all over Germany and the world. The visitor centre at the Ketzin site is run by GFZ and the most important contact point to inform about first-hand experiences from the project. Up to now, about 3,000 visitors came to the Ketzin site for guided tours and the annual open house days. In addition, project status and progress are disseminated in brochures and on the public website www.co2ketzin.de. The Ketzin project is also presented in short films, e.g. on monitoring, drilling and well closure. As the post-closure and pre-transfer phase started after the cease of CO2 injection in August 2013 and the injection facility was dismantled in December 2013, we were looking for a tool to further inform about the previous operation and site infrastructure. A virtual tour was set up for the Ketzin site which is accessible via the website. This tour includes several videos which virtually guide you on site and provide information on the (former) facilities. Public acceptance is a key issue for the Ketzin project as it is for any other CO2 storage project. For example, an open communication with the local residents helped to conduct large-scale seismic campaigns without severe restrictions. The experience from the Ketzin pilot site shows that honest communication and a diverse dissemination program is able to overcome critical public perception even for highly debated technologies.

  4. 76 FR 43960 - NARA Records Reproduction Fees

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... transferred to NARA and maintain its fee schedule on NARA's Web site http://www.archives.gov . The proposed... document is faint or too dark, it requires additional time to obtain a readable image. In TABLE 1 below... our Web site ( http://www.archives.gov ) annually when announcing that records reproduction fees will...

  5. 31 CFR 380.5 - Where can I find current information, and who can I contact for additional guidance and...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... valuations on Treasury's Bureau of the Fiscal Service Web site at http://www.treasurydirect.gov. You may also... 9th Street, NW., 8th Floor, Washington, DC 20239-0001, or by e-mail at [email protected]gov. ...

  6. The influence of question design on the response to self-assessment in www.elearnSCI.org: a submodule pilot study.

    PubMed

    Liu, N; Li, X-W; Zhou, M-W; Biering-Sørensen, F

    2015-08-01

    This is an interventional training session. The objective of this study was to investigate the difference in response to self-assessment questions in the original and an adjusted version for a submodule of www.elearnSCI.org for student nurses. The study was conducted in a teaching hospital affiliated to Peking University, China. In all, 28 student nurses divided into two groups (groups A and B; 14 in each) received a print-out of a Chinese translation of the slides from the 'Maintaining skin integrity following spinal cord injury' submodule in www.elearnSCI.org for self-study. Both groups were then tested using the 10 self-assessment multiple-choice questions (MCQs) related to the same submodule. Group A used the original questions, whereas group B received an adjusted questionnaire. The responses to four conventional single-answer MCQs were nearly all correct in both groups. However, in three questions, group A, with the option 'All of the above', had a higher number of correct answers than group B, with multiple-answer MCQs. In addition, in another three questions, group A, using the original multiple-answer MCQs, had fewer correct answers than group B, where it was only necessary to tick a single incorrect answer. Variations in design influence the response to questions. The use of conventional single-answer MCQs should be reconsidered, as they only examine the recall of isolated knowledge facts. The 'All of the above' option should be avoided because it would increase the number of correct answers arrived at by guessing. When using multiple-answer MCQs, it is recommended that the questions asked should be in accordance with the content within the www.elearnSCI.org.

  7. Using a Web Site in an Elementary Science Methods Class: Are We Opening a Pandora's Box?

    ERIC Educational Resources Information Center

    Lewis, Scott P.; O'Brien, George E.

    This paper describes the introduction and use of the World Wide Web (WWW) in an elementary science methods course at Florida International University (FIU). The goals of creating a web site include engaging conversations among educators, providing access to local resources for students, and examining student use of web sites and the Internet. The…

  8. A web site on lung cancer: who are the users and what are they looking for?

    PubMed

    Linssen, Cilia; Schook, Romane M; The, Anne-Mei; Lammers, Ernst; Festen, Jan; Postmus, Pieter E

    2007-09-01

    site are caregivers (57%), patients (8%), and others (students, people fearing lung cancer). Of the visitors, 895 found what they were looking for, and the satisfaction is the highest among nurses and caregivers (91% and 95%, respectively) and the lowest among physicians and patients (85% and 83%). Given the number of visitors to the lung cancer Web site, it can be concluded that there is a great need for additional information among patients and caregivers. The launched Web site www.longkanker.info has reached its goal of providing a dependable source of information about lung cancer and satisfying its visitors.

  9. A User-centered Model for Web Site Design

    PubMed Central

    Kinzie, Mable B.; Cohn, Wendy F.; Julian, Marti F.; Knaus, William A.

    2002-01-01

    As the Internet continues to grow as a delivery medium for health information, the design of effective Web sites becomes increasingly important. In this paper, the authors provide an overview of one effective model for Web site design, a user-centered process that includes techniques for needs assessment, goal/task analysis, user interface design, and rapid prototyping. They detail how this approach was employed to design a family health history Web site, Health Heritage <www.healthheritage.net>. This Web site helps patients record and maintain their family health histories in a secure, confidential manner. It also supports primary care physicians through analysis of health histories, identification of potential risks, and provision of health care recommendations. Visual examples of the design process are provided to show how the use of this model resulted in an easy-to-use Web site that is likely to meet user needs. The model is effective across diverse content arenas and is appropriate for applications in varied media. PMID:12087113

  10. 76 FR 44579 - Notice of Availability of Environmental Assessment for Strike Fighter Realignment at Naval Air...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-26

    ... Engineering Command, Southwest; Attn: Code EV21.AK; 1220 Pacific Highway, Building 1, 5th Floor; San Diego, CA... available for public review at the following Web site: http://www.cnic.navy.mil/cnrsw . In addition, paper... language informational materials will be made available on the Web site: http://www.cnic.navy.mil/cnrsw and...

  11. 75 FR 51434 - Hazardous and Solid Waste Management System; Identification and Listing of Special Wastes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... characters, any form of encryption, and be free of any defects or viruses. For additional information about... hearings can be found on EPA's Web site at: http://www.epa.gov/epawaste/nonhaz/industrial/special/fossil... information on the Web site: http://www.epa.gov/osw/nonhaz/industrial/special/fossil/ccr-rule/ccr-webinar.htm...

  12. Planetary Science Research Discoveries (PSRD) www.psrd.hawaii.edu

    NASA Astrophysics Data System (ADS)

    Martel, L.; Taylor, J.

    2010-12-01

    NASA's Year of the Solar System is celebrating not only Solar System mission milestones but also the collective data reduction and analysis that happens here on Earth. The Cosmochemistry Program of NASA's Science Mission Directorate takes a direct approach to enhance student learning and engage the public in the latest research on meteorites, asteroids, planets, moons, and other materials in our Solar System with the website known as PSRD. The Planetary Science Research Discoveries (PSRD) website at www.psrd.hawaii.edu explores the science questions that researchers are actively pursuing about our Solar System and explains how the answers are discovered and what they mean. The site helps to convey the scientific basis for sample study to the broader scientific community and the excitement of new results in cosmochemistry to the general public. We share with our broad audience the fascinating discoveries made by cosmochemists, increasing public awareness of the value of sample-focused research in particular and of fundamental scientific research and space exploration in general. The scope of the website covers the full range of cosmochemical research and highlights the investigations of extraterrestrial materials that are used to better understand the origin of the Solar System and the processes by which planets, moons, and small bodies evolve. We relate the research to broader planetary science themes and mission results. Articles are categorized into: asteroids, comets, Earth, instruments of cosmochemistry, Jupiter system, Mars, Mars life issues, Mercury, meteorites, Moon, origins, and space weathering. PSRD articles are based on peer-reviewed, journal publications. Some PSRD articles are based on more than one published paper in order to present multiple views and outcomes of research on a topic of interest. To date, 150 PSRD articles have been based on 184 journal articles (and counting) written by some of the most active cosmochemists and planetary scientists

  13. Long-term application of winery wastewater - Effect on soil microbial populations and soil chemistry

    NASA Astrophysics Data System (ADS)

    Mosse, Kim; Patti, Antonio; Smernik, Ron; Cavagnaro, Timothy

    2010-05-01

    The ability to reuse winery wastewater (WWW) has potential benefits both with respect to treatment of a waste stream, as well as providing a beneficial water resource in water limited regions such as south-eastern Australia, California and South Africa. Over an extended time period, this practice leads to changes in soil chemistry, and potentially, also to soil microbial populations. In this study, we compared the short term effects of WWW (both treated and untreated) application on soil biology and chemistry in two adjacent paired sites with the same soil type, one of which had received WWW for approximately 30 years, and the other which had not. The paired sites were treated with an industrially relevant quantity of WWW, and the soil microbial activity (measured as soil CO2 efflux) and common soil physicochemical properties were monitored over a 16-day period. In addition, Solid State 13C NMR was employed on whole soil samples from the two sites, to measure and compare the chemical nature of the soil organic matter at the paired sites. The acclimatised soil showed a high level of organic matter and a greater spike in microbial activity following WWW addition, in comparison with the non-acclimatised soil, suggesting differences in soil chemistry and soil microbial communities between the two sites. Soil nitrate and phosphorus levels showed significant differences between WWW treatments; these differences likely to be microbially mediated.

  14. 78 FR 29752 - Notification of a Public Teleconference of the Clean Air Act Advisory Committee (CAAAC)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... prepared for the meeting will be publicly available on the CAAAC Web site at http://www.epa.gov/oar/caaac... . Additional information on these meetings can be found on the CAAAC Web site: http://www.epa.gov/oar/caaac... Craig at (202) 564-1674 or [email protected] , preferably at least 10 days prior to the meeting to...

  15. Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites.

    PubMed

    Ribeiro, António J M; Holliday, Gemma L; Furnham, Nicholas; Tyzack, Jonathan D; Ferris, Katherine; Thornton, Janet M

    2018-01-04

    M-CSA (Mechanism and Catalytic Site Atlas) is a database of enzyme active sites and reaction mechanisms that can be accessed at www.ebi.ac.uk/thornton-srv/m-csa. Our objectives with M-CSA are to provide an open data resource for the community to browse known enzyme reaction mechanisms and catalytic sites, and to use the dataset to understand enzyme function and evolution. M-CSA results from the merging of two existing databases, MACiE (Mechanism, Annotation and Classification in Enzymes), a database of enzyme mechanisms, and CSA (Catalytic Site Atlas), a database of catalytic sites of enzymes. We are releasing M-CSA as a new website and underlying database architecture. At the moment, M-CSA contains 961 entries, 423 of these with detailed mechanism information, and 538 with information on the catalytic site residues only. In total, these cover 81% (195/241) of third level EC numbers with a PDB structure, and 30% (840/2793) of fourth level EC numbers with a PDB structure, out of 6028 in total. By searching for close homologues, we are able to extend M-CSA coverage of PDB and UniProtKB to 51 993 structures and to over five million sequences, respectively, of which about 40% and 30% have a conserved active site. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  16. 48 CFR 8.402 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... System.) Ordering activities may access GSA Advantage! through the GSA Federal Supply Service Home Page (http://www.gsa.gov/fss) or the GSA Federal Supply Schedule Home Page at http://www.gsa.gov/schedules..., review the following Web site: http://www.gsa.gov/schedules. Additionally, for on-line training courses...

  17. www.fallasdechile.cl, the First Online Repository for Neotectonic Faults in the Chilean Andes

    NASA Astrophysics Data System (ADS)

    Aron, F.; Salas, V.; Bugueño, C. J.; Hernández, C.; Leiva, L.; Santibanez, I.; Cembrano, J. M.

    2016-12-01

    We introduce the site www.fallasdechile.cl, created and maintained by undergraduate students and researchers at the Catholic University of Chile. Though the web page seeks to inform and educate the general public about potentially seismogenic faults of the country, layers of increasing content complexity allow students, researchers and educators to consult the site as a scientific tool as well. This is the first comprehensive, open access database on Chilean geologic faults; we envision that it may grow organically with contributions from peer scientists, resembling the SCEC community fault model for southern California. Our website aims at filling a gap between science and society providing users the opportunity to get involved by self-driven learning through interactive education modules. The main page highlights recent developments and open questions in Chilean earthquake science. Front pages show first level information of general concepts in earthquake topics such as tectonic settings, definition of geologic faults, and space-time constraints of faults. Users can navigate interactive modules to explore, with real data, different earthquake scenarios and compute values of seismic moment and magnitude. A second level covers Chilean/Andean faults classified according to their geographic location containing at least one of the following parameters: mapped trace, 3D geometry, sense of slip, recurrence times and date of last event. Fault traces are displayed on an interactive map using a Google Maps API. The material is compiled and curated in an effort to present, up to our knowledge, accurate and up to date information. If interested, the user can navigate to a third layer containing more advanced technical details including primary sources of the data, a brief structural description, published scientific articles, and links to other online content complementing our site. Also, geographically referenced fault traces with attributes (kml, shapefiles) and fault 3D

  18. Microwave-induced activation of additional active edge sites on the MoS2 surface for enhanced Hg0 capture

    NASA Astrophysics Data System (ADS)

    Zhao, Haitao; Mu, Xueliang; Yang, Gang; Zheng, Chengheng; Sun, Chenggong; Gao, Xiang; Wu, Tao

    2017-10-01

    In recent years, significant effort has been made in the development of novel materials for the removal of mercury from coal-derived flue gas. In this research, microwave irradiation was adopted to induce the creation of additional active sites on the MoS2 surface. The results showed that Hg0 capture efficiency of the adsorbent containing MoS2 nanosheets being microwave treated was as high as 97%, while the sample prepared via conventional method only showed an efficiency of 94% in its first 180 min testing. After the adsorbent was treated by microwave irradiation for 3 more times, its mercury removal efficiency was still noticeably higher than that of the sample prepared via conventional method. Characterization of surface structure of the MoS2 containing material together with DFT study further revealed that the (001) basal planes of MoS2 crystal structure were cracked into (100) edge planes (with an angle of approximately 75°) under microwave treatment, which subsequently resulted in the formation of additional active edge sites on the MoS2 surface and led to the improved performance on Hg0 capture.

  19. 75 FR 63865 - National Science Board; Sunshine Act Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

    ... the National Science Board Web site http:[sol][sol]www.nsf.gov/nsb for additional information and schedule updates (time, place, subject matter or status of meeting) may be found at http:[sol][sol]www.nsf...

  20. 76 FR 3180 - National Science Board; Sunshine Act Meetings; Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-19

    ... Board Web site http:[sol][sol]www.nsf.gov/nsb for additional information and schedule updates (time, place, subject matter or status of meeting) may be found at http:[sol][sol]www.nsf.gov/nsb/notices...

  1. Documentation for a web site to serve ULF-EM (Ultra-Low Frequency Electromagnetic) data to the public

    USGS Publications Warehouse

    Neumann, Danny A.; McPherson, Selwyn; Klemperer, Simon L.; Glen, Jonathan M.G.; McPhee, Darcy K.; Kappler, Karl

    2011-01-01

    The Stanford Ultra-Low Frequency Electromagnetic (ULF-EM) Monitoring Project is recording naturally varying electromagnetic signals adjacent to active earthquake faults, in an attempt to establish whether there is any variation in these signals associated with earthquakes. Our project is collaborative between Stanford University, the U.S. Geological Survey (USGS), and UC Berkeley. Lead scientists are Simon Klemperer (Stanford University), Jonathan Glen (USGS) and Darcy Karakelian McPhee (USGS). Our initial sites are in the San Francisco Bay Area, monitoring different strands of the San Andreas fault system, at Stanford University's Jasper Ridge Biological Preserve (JRSC), Marin Headlands of the Golden Gate National Recreation Area (MHDL), and the UC Berkeley's Russell Reservation Field Station adjacent to Briones Regional Park (BRIB). In addition, we maintain in conjunction with the Berkeley Seismological Laboratory (BSL) two remote reference stations at the Bear Valley Ranch in Parkfield, Calif., (PKD) and the San Andreas Geophysical Observatory at Hollister, Calif., (SAO). Metadata about our site can be found at http://ulfem-data.stanford.edu/info.html. Site descriptions can be found at the BSL at http://seismo.berkeley.edu/, and seismic data can be obtained from the Northern California Earthquake Data Center at http://www.ncedc.org/. The site http://ulfem-data.stanford.edu/ allows access to data from the Stanford-USGS sites JRSC, MHDL and BRIB, as well as UC Berkeley sites PKD and SAO.

  2. 2013 Annual Site Inspection and Monitoring Report for Uranium Mill Tailings Radiation Control Act Title II Disposal Sites

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    This report, in fulfillment of a license requirement, presents the results of long-term surveillance and maintenance activities conducted by the U.S. Department of Energy (DOE) Office of Legacy Management in 2013 at six uranium mill tailings disposal sites reclaimed under Title II of the Uranium Mill Tailings Radiation Control Act (UMTRCA) of 1978. These activities verified that the UMTRCA Title II disposal sites remain in compliance with license requirements. DOE manages six UMTRCA Title II disposal sites under a general license granted by the U.S. Nuclear Regulatory Commission (NRC) established at Title 10 Code of Federal Regulations Part 40.28. Reclamationmore » and site transition activities continue at other sites, and DOE ultimately expects to manage approximately 27 Title II disposal sites. Long-term surveillance and maintenance activities and services for these disposal sites include inspecting and maintaining the sites; monitoring environmental media and institutional controls; conducting any necessary corrective action; and performing administrative, records, stakeholder services, and other regulatory functions. Annual site inspections and monitoring are conducted in accordance with site-specific long-term surveillance plans (LTSPs) and procedures established by DOE to comply with license requirements. Each site inspection is performed to verify the integrity of visible features at the site; to identify changes or new conditions that may affect the long-term performance of the site; and to determine the need, if any, for maintenance, follow-up inspections, or corrective action. LTSPs and site compliance reports are available online at http://www.lm.doe.gov« less

  3. "WWW.MDTF.ORG": a World Wide Web forum for developing open-architecture, freely distributed, digital teaching file software by participant consensus.

    PubMed

    Katzman, G L; Morris, D; Lauman, J; Cochella, C; Goede, P; Harnsberger, H R

    2001-06-01

    To foster a community supported evaluation processes for open-source digital teaching file (DTF) development and maintenance. The mechanisms used to support this process will include standard web browsers, web servers, forum software, and custom additions to the forum software to potentially enable a mediated voting protocol. The web server will also serve as a focal point for beta and release software distribution, which is the desired end-goal of this process. We foresee that www.mdtf.org will provide for widespread distribution of open source DTF software that will include function and interface design decisions from community participation on the website forums.

  4. Did You Just See that? Online Video Sites Can Jumpstart Lessons

    ERIC Educational Resources Information Center

    Oishi, Lindsay

    2007-01-01

    Free video sharing Web sites like www.youtube.com allow millions of people to witness videos that are free and can be viewed immediately without having to download any software. These videos do not provide content, but they can stimulate the interest that makes curriculum relevant or "jumpstart" lessons. The YouTube video blog of World War II…

  5. Effectiveness of the addition of Lidocaine to a hemostatic, bioresorbable putty in the treatment of iliac crest donor site pain.

    PubMed

    Müller, Marc Andreas; Mehrkens, Arne; Zürcher, Roman; Vavken, Patrick; Valderrabano, Victor

    2014-12-08

    The harvest of iliac crest bone grafts (ICBG) is associated with relevant donor site pain, but may be lowered by the application of lidocaine loaded on biodegradable, hemostatic putty for sustained local analgesic release. The goal of this double-blind controlled trial was to assess the efficacy of adding lidocaine to a hemostatic putty (Orthostat ™) to treat donor site pain following harvest of ICBG in foot and ankle procedures. After ICBG harvest during a foot and ankle procedure, the resulting bone defect was either filled with Orthostat™ (n = 7) or with the same hemostatic putty loaded with lidocaine (Orthostat-L™, n = 7). During the first 72 postoperative hours, donor site and surgical site pain were managed by patient controlled morphine delivery and a peripheral nerve block. Donor site pain was periodically quantified on a Visual Analog (VAS) and a Wong Baker FACES scale. Pain scores were plotted over time to calculate the area under the curve (AUC) to quantify the overall pain experienced in specific time intervals. Orthostat-L™ significantly reduced donor site pain over the first 12 hours postoperatively as evidenced by a significant decrease of the AUC in both VAS (p = 0.0366) and Wong Baker FACES pain score plots (p = 0.0024). Cumulated morphine uses were not significantly decreased with Orthostat-L™. The addition of lidocaine to a hemostatic putty offers a significant ICBG donor site pain reduction over the first 12 postoperative hours. ClinicalTrials.gov NCT01504035. Registered January 2nd 2012.

  6. [WWW.2CHEAT.COM] Update

    ERIC Educational Resources Information Center

    Rooks, Clay D.

    2006-01-01

    This paper is an updated presentation on the subject of cheating and plagiarism via the World Wide Web. In a few hours searching the Internet, the author found even more "cheat" sites than in 1998 that offered not only all types of term and research papers, but college admission letters, reviews, case studies, even dissertations as well. Most now…

  7. 77 FR 18243 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-27

    ... of Energy Information Center, 1 Science.gov Way, Oak Ridge, Tennessee 37830. FOR FURTHER INFORMATION... 2001, EM-90, Oak Ridge, TN 37831. Phone (865) 241-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em/ssab . SUPPLEMENTARY INFORMATION: Purpose of the...

  8. 77 FR 38275 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... of Energy Information Center, 1 Science.gov Way, Oak Ridge, Tennessee 37830. FOR FURTHER INFORMATION... 2001, EM-90, Oak Ridge, TN 37831. Phone (865) 241-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em/ssab . SUPPLEMENTARY INFORMATION: Purpose of the...

  9. 77 FR 23470 - Environmental Management Site-Specific Advisory Board, Oak Ridge Reservation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-19

    ... Energy Information Center, 1 Science.gov Way, Oak Ridge, Tennessee 37830. FOR FURTHER INFORMATION CONTACT...-90, Oak Ridge, TN 37831. Phone (865) 241-3315; Fax (865) 576-0956 or email: [email protected]gov or check the Web site at www.oakridge.doe.gov/em/ssab . SUPPLEMENTARY INFORMATION: Purpose of the Board...

  10. The EuroSITES network: Integrating and enhancing fixed-point open ocean observatories around Europe

    NASA Astrophysics Data System (ADS)

    Lampitt, Richard S.; Larkin, Kate E.; EuroSITES Consortium

    2010-05-01

    EuroSITES is a 3 year (2008-2011) EU collaborative project (3.5MEuro) with the objective to integrate and enhance the nine existing open ocean fixed point observatories around Europe (www.eurosites.info). These observatories are primarily composed of full depth moorings and make multidisciplinary in situ observations within the water column as the European contribution to the global array OceanSITES (www.oceansites.org). In the first 18 months, all 9 observatories have been active and integration has been significant through the maintenance and enhancement of observatory hardware. Highlights include the enhancement of observatories with sensors to measure O2, pCO2, chlorophyll, and nitrate in near real-time from the upper 1000 m. In addition, some seafloor missions are also actively supported. These include seafloor platforms currently deployed in the Mediterranean, one for tsunami detection and one to monitor fluid flow related to seismic activity and slope stability. Upcoming seafloor science missions in 2010 include monitoring benthic biological communities and associated biogeochemistry as indicators of climate change in both the Northeast Atlantic and Mediterranean. EuroSITES also promotes the development of innovative sensors and samplers in order to progress capability to measure climate-relevant properties of the ocean. These include further developing current technologies for autonomous long-term monitoring of oxygen consumption in the mesopelagic, pH and mesozooplankton abundance. Many of these science missions are directly related to complementary activities in other European projects such as EPOCA, HYPOX and ESONET. In 2010 a direct collaboration including in situ field work will take place between ESONET and EuroSITES. The demonstration mission MODOO (funded by ESONET) will be implemented in 2010 at the EuroSITES PAP observatory. Field work will include deployment of a seafloor lander system with various sensors which will send data to shore in real

  11. LIBRA-WA: a web application for ligand binding site detection and protein function recognition.

    PubMed

    Toti, Daniele; Viet Hung, Le; Tortosa, Valentina; Brandi, Valentina; Polticelli, Fabio

    2018-03-01

    Recently, LIBRA, a tool for active/ligand binding site prediction, was described. LIBRA's effectiveness was comparable to similar state-of-the-art tools; however, its scoring scheme, output presentation, dependence on local resources and overall convenience were amenable to improvements. To solve these issues, LIBRA-WA, a web application based on an improved LIBRA engine, has been developed, featuring a novel scoring scheme consistently improving LIBRA's performance, and a refined algorithm that can identify binding sites hosted at the interface between different subunits. LIBRA-WA also sports additional functionalities like ligand clustering and a completely redesigned interface for an easier analysis of the output. Extensive tests on 373 apoprotein structures indicate that LIBRA-WA is able to identify the biologically relevant ligand/ligand binding site in 357 cases (∼96%), with the correct prediction ranking first in 349 cases (∼98% of the latter, ∼94% of the total). The earlier stand-alone tool has also been updated and dubbed LIBRA+, by integrating LIBRA-WA's improved engine for cross-compatibility purposes. LIBRA-WA and LIBRA+ are available at: http://www.computationalbiology.it/software.html. polticel@uniroma3.it. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  12. 76 FR 54195 - 2010 Resources Planning Act (RPA) Assessment Draft

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ... Resources Planning Act (RPA) Assessment is available for review and comment at http://www.fs.fed.us/research... facsimile to 703-605-5131 or by email using the comment form on the Web site http://www.fs.fed.us/research... . Additional information about the RPA Assessment can be obtained on the Internet at http://www.fs.fed.us...

  13. Secure Web-Site Access with Tickets and Message-Dependent Digests

    USGS Publications Warehouse

    Donato, David I.

    2008-01-01

    Although there are various methods for restricting access to documents stored on a World Wide Web (WWW) site (a Web site), none of the widely used methods is completely suitable for restricting access to Web applications hosted on an otherwise publicly accessible Web site. A new technique, however, provides a mix of features well suited for restricting Web-site or Web-application access to authorized users, including the following: secure user authentication, tamper-resistant sessions, simple access to user state variables by server-side applications, and clean session terminations. This technique, called message-dependent digests with tickets, or MDDT, maintains secure user sessions by passing single-use nonces (tickets) and message-dependent digests of user credentials back and forth between client and server. Appendix 2 provides a working implementation of MDDT with PHP server-side code and JavaScript client-side code.

  14. 76 FR 79228 - Combined Licenses at William States Lee III Nuclear Station Site, Units 1 and 2; Duke Energy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-21

    ... William States Lee III Nuclear Station Site, Units 1 and 2; Duke Energy Carolinas, LLC AGENCY: Nuclear... Statement for Combined Licenses (COL) for William States Lee III Nuclear Station Units 1 and 2 [Lee Nuclear... draft EIS can be accessed online at the NRC's William States Lee III Nuclear Site Web page at http://www...

  15. Cluster-Randomized Trial of Personalized Site Performance Feedback in Get With The Guidelines-Heart Failure.

    PubMed

    DeVore, Adam D; Cox, Margueritte; Heidenreich, Paul A; Fonarow, Gregg C; Yancy, Clyde W; Eapen, Zubin J; Peterson, Eric D; Hernandez, Adrian F

    2015-07-01

    There is significant variation in the delivery of evidence-based care for patients with heart failure (HF), but there is limited evidence defining the best methods to improve the quality of care. We performed a cluster-randomized trial of personalized site performance feedback at 147 hospitals participating in the Get With The Guidelines-Heart Failure quality improvement program from October 2009 to March 2011. The intervention provided sites with specific data on their heart failure achievement and quality measures in addition to the usual Get With The Guidelines-Heart Failure tools. The primary outcome for our trial was improvement in site composite quality of care score. Overall, 73 hospitals (n=33 886 patients) received the intervention, whereas 74 hospitals (n=37 943 patients) did not. One year after the intervention, both the intervention and control arms had a similar mean change in percentage points in their composite quality score (absolute change, +0.31 [SE, 1.51] versus +3.18 [SE, 1.68] in control; P=0.21). Similarly, none of the individual achievement measures or quality measures improved more at intervention versus control hospitals. Our site-based intervention, which included personalized site feedback on adherence to quality metrics, was not able to elicit more quality improvement beyond that already associated with participation in the Get With The Guidelines-Heart Failure program. URL: http://www.clinicaltrials.gov. Unique identifier: NCT00979264. © 2015 American Heart Association, Inc.

  16. 78 FR 37222 - Columbia Organic Chemical Company Site, Columbia, Richland County, South Carolina; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9826-7; CERCLA-04-2013-3761] Columbia Organic Chemical... Agency has entered into a settlement with Stephen Reichlyn concerning the Columbia Organic Chemical... comments by site name Columbia Organic Chemical Company by one of the following methods: www.epa.gov...

  17. Seeing and Reading Red: Hue and Color-word Correlation in Images and Attendant Text on the WWW

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Newsam, S

    2004-07-12

    This work represents an initial investigation into determining whether correlations actually exist between metadata and content descriptors in multimedia datasets. We provide a quantitative method for evaluating whether the hue of images on the WWW is correlated with the occurrence of color-words in metadata such as URLs, image names, and attendant text. It turns out that such a correlation does exist: the likelihood that a particular color appears in an image whose URL, name, and/or attendant text contains the corresponding color-word is generally at least twice the likelihood that the color appears in a randomly chosen image on the WWW.more » While this finding might not be significant in and of itself, it represents an initial step towards quantitatively establishing that other, perhaps more useful correlations exist. These correlations form the basis for exciting novel approaches that leverage semi-supervised datasets, such as the WWW, to overcome the semantic gap that has hampered progress in multimedia information retrieval for some time now.« less

  18. Phosphate additives in food--a health risk.

    PubMed

    Ritz, Eberhard; Hahn, Kai; Ketteler, Markus; Kuhlmann, Martin K; Mann, Johannes

    2012-01-01

    Hyperphosphatemia has been identified in the past decade as a strong predictor of mortality in advanced chronic kidney disease (CKD). For example, a study of patients in stage CKD 5 (with an annual mortality of about 20%) revealed that 12% of all deaths in this group were attributable to an elevated serum phosphate concentration. Recently, a high-normal serum phosphate concentration has also been found to be an independent predictor of cardiovascular events and mortality in the general population. Therefore, phosphate additives in food are a matter of concern, and their potential impact on health may well have been underappreciated. We reviewed pertinent literature retrieved by a selective search of the PubMed and EU databases (www.zusatzstoffe-online.de, www.codexalimentarius.de), with the search terms "phosphate additives" and "hyperphosphatemia." There is no need to lower the content of natural phosphate, i.e. organic esters, in food, because this type of phosphate is incompletely absorbed; restricting its intake might even lead to protein malnutrition. On the other hand, inorganic phosphate in food additives is effectively absorbed and can measurably elevate the serum phosphate concentration in patients with advanced CKD. Foods with added phosphate tend to be eaten by persons at the lower end of the socioeconomic scale, who consume more processed and "fast" food. The main pathophysiological effect of phosphate is vascular damage, e.g. endothelial dysfunction and vascular calcification. Aside from the quality of phosphate in the diet (which also requires attention), the quantity of phosphate consumed by patients with advanced renal failure should not exceed 1000 mg per day, according to the guidelines. Prospective controlled trials are currently unavailable. In view of the high prevalence of CKD and the potential harm caused by phosphate additives to food, the public should be informed that added phosphate is damaging to health. Furthermore, calls for labeling

  19. www.elearnSCI.org: a global educational initiative of ISCoS.

    PubMed

    Chhabra, H S; Harvey, L A; Muldoon, S; Chaudhary, S; Arora, M; Brown, D J; Biering-Sorensen, F; Wyndaele, J J; Charlifue, S; Horsewell, J; Ducharme, S; Green, D; Simpson, D; Glinsky, J; Weerts, E; Upadhyay, N; Aito, S; Wing, P; Katoh, S; Kovindha, A; Krassioukov, A; Weeks, C; Srikumar, V; Reeves, R; Siriwardane, C; Hasnan, N; Kalke, Y B; Lanig, I

    2013-03-01

    To develop a web-based educational resource for health professionals responsible for the management of spinal cord injury (SCI). The resource:www.elearnSCI.org is comprised of seven learning modules, each subdivided into various submodules. Six of the seven modules address the educational needs of all disciplines involved in comprehensive SCI management. The seventh module addresses prevention of SCI. Each submodule includes an overview, activities, self-assessment questions and references. Three hundred and thirty-two experts from The International Spinal Cord Society (ISCoS) and various affiliated societies from 36 countries were involved in developing the resource through 28 subcommittees. The content of each submodule was reviewed and approved by the Education and Scientific Committees of ISCoS and finally by an Editorial Committee of 23 experts. The content of the learning modules is relevant to students and to new as well as experienced SCI healthcare professionals. The content is applicable globally, has received consumer input and is available at no cost. The material is presented on a website underpinned by a sophisticated content-management system, which allows easy maintenance and ready update of all the content. The resource conforms to key principles of e-learning, including appropriateness of curriculum, engagement of learners, innovative approaches, effective learning, ease of use, inclusion, assessment, coherence, consistency, transparency, cost effectiveness and feedback. www.elearnSCI.org provides a cost effective way of training healthcare professionals that goes beyond the textbook and traditional face-to-face teaching.

  20. Online sea ice data platform: www.seaiceportal.de

    NASA Astrophysics Data System (ADS)

    Nicolaus, Marcel; Asseng, Jölund; Bartsch, Annekathrin; Bräuer, Benny; Fritzsch, Bernadette; Grosfeld, Klaus; Hendricks, Stefan; Hiller, Wolfgang; Heygster, Georg; Krumpen, Thomas; Melsheimer, Christian; Ricker, Robert; Treffeisen, Renate; Weigelt, Marietta; Nicolaus, Anja; Lemke, Peter

    2016-04-01

    There is an increasing public interest in sea ice information from both Polar Regions, which requires up-to-date background information and data sets at different levels for various target groups. In order to serve this interest and need, seaiceportal.de (originally: meereisportal.de) was developed as a comprehensive German knowledge platform on sea ice and its snow cover in the Arctic and Antarctic. It was launched in April 2013. Since then, the content and selection of data sets increased and the data portal received increasing attention, also from the international science community. Meanwhile, we are providing near-real time and archive data of many key parameters of sea ice and its snow cover. The data sets result from measurements acquired by various platforms as well as numerical simulations. Satellite observations of sea ice concentration, freeboard, thickness and drift are available as gridded data sets. Sea ice and snow temperatures and thickness as well as atmospheric parameters are available from autonomous platforms (buoys). Additional ship observations, ice station measurements, and mooring time series are compiled as data collections over the last decade. In parallel, we are continuously extending our meta-data and uncertainty information for all data sets. In addition to the data portal, seaiceportal.de provides general comprehensive background information on sea ice and snow as well as expert statements on recent observations and developments. This content is mostly in German in order to complement the various existing international sites for the German speaking public. We will present the portal, its content and function, but we are also asking for direct user feedback.

  1. 78 FR 44119 - Circle Environmental #1 Superfund Site; Dawson, Terrell County, Georgia; Notice of Settlement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ... ENVIRONMENTAL PROTECTION AGENCY [FRL-9837-3; CERCLA-04-2013-3760] Circle Environmental 1 Superfund... settlement with Walter G. Mercer, Jr. concerning the Circle Environmental 1 Superfund Site located in Dawson... methods: Internet: www.epa.gov/region4/superfund/programs/enforcement/enforcement.html U.S. Mail: U.S...

  2. 78 FR 70551 - Macalloy Superfund Site, North Charleston, Charleston County, South Carolina; Notice of Settlement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-26

    ... ENVIRONMENTAL PROTECTION AGENCY [CERCLA-04-2014-3750; FRL 9903-42-Region 4] Macalloy Superfund...., addressing past costs and a portion of future costs concerning the Macalloy Superfund Site located in North... following methods: Internet: www.epa.gov/region4/superfund/programs/enforcement/enforcement.html . U.S. Mail...

  3. Factors predicting publication of spinal cord injury trials registered on www.ClinicalTrials. gov.

    PubMed

    DePasse, J Mason; Park, Sara; Eltorai, Adam E M; Daniels, Alan H

    2018-02-06

    Treatment options for spinal cord injuries are currently limited, but multiple clinical trials are underway for a variety of interventions, drugs, and devices. The Food and Drug Administration website www.ClinicalTrials.gov catalogues these trials and includes information on the status of the trial, date of initiation and completion, source of funding, and region. This investigation assesses the factors associated with publication and the publication rate of spinal cord injury trials. Retrospective analysis of publically available data on www.ClinicalTrials.gov. The www.ClinicalTrials.gov was queried for all trials on patients with spinal cord injury, and these trials were assessed for status, type of intervention, source of funding, and region. Multiple literature searches were performed on all completed trials to determine publication status. There were 626 studies identified concerning the treatment of patients with spinal cord injury, of which 250 (39.9%) were completed. Of these, only 119 (47.6%) were published. There was no significant difference in the rate of publication between regions (p> 0.16) or by study type (p> 0.29). However, trials that were funded by the NIH were more likely to be published than trials funded by industry (p= 0.01). The current publication rate of spinal cord injury trials is only 47.6%, though this rate is similar to the publication rate for trials in other fields. NIH-funded trials are significantly more likely to become published than industry-funded trials, which could indicate that some trials remain unpublished due to undesirable results. However, it is also likely that many trials on spinal cord injury yield negative results, as treatments are often ineffective.

  4. On-Site Additive Manufacturing by Selective Laser Melting of Composite Objects

    NASA Astrophysics Data System (ADS)

    Fateri, M.; Khosravi, M.

    2012-06-01

    This paper proposes a method for cost reduction of future space missions by manufacturing parts on foreign planets. The suitability of Selective Laser Melting process for on-site production of metallic, ceramic and glass products on mars is examined.

  5. Pulp fiction - The volunteer concept (or how not to site additional LLRW disposal capacity)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burton, D.A.

    1995-12-31

    Experiences of compacts and of individual states throughout the nation indicate that low-level radioactive waste disposal siting processes, based from the beginning upon the volunteer concept are fraught with problems. Most apparent among these problems is that the volunteer concept does not lead to scientifically and technically based siting endeavors. Ten years have passed since the Amendments Act of 1985, and no compact or state has been - successful in providing for new LLRW disposal capacity. That failure can be traced in part to the reliance upon the volunteer concept in siting attempts. If success is to be achieved, themore » future direction for LLRW management must focus on three areas: first, a comprehensive evaluation of all LLRW management options, including reduction of waste generated and on-site storage; secondly, a comprehensive evaluation of the current as well as projected waste stream, to determine the amount of disposal capacity actually needed; and, finally, sound scientifically and technically based siting processes.« less

  6. QuickMap: a public tool for large-scale gene therapy vector insertion site mapping and analysis.

    PubMed

    Appelt, J-U; Giordano, F A; Ecker, M; Roeder, I; Grund, N; Hotz-Wagenblatt, A; Opelz, G; Zeller, W J; Allgayer, H; Fruehauf, S; Laufs, S

    2009-07-01

    Several events of insertional mutagenesis in pre-clinical and clinical gene therapy studies have created intense interest in assessing the genomic insertion profiles of gene therapy vectors. For the construction of such profiles, vector-flanking sequences detected by inverse PCR, linear amplification-mediated-PCR or ligation-mediated-PCR need to be mapped to the host cell's genome and compared to a reference set. Although remarkable progress has been achieved in mapping gene therapy vector insertion sites, public reference sets are lacking, as are the possibilities to quickly detect non-random patterns in experimental data. We developed a tool termed QuickMap, which uniformly maps and analyzes human and murine vector-flanking sequences within seconds (available at www.gtsg.org). Besides information about hits in chromosomes and fragile sites, QuickMap automatically determines insertion frequencies in +/- 250 kb adjacency to genes, cancer genes, pseudogenes, transcription factor and (post-transcriptional) miRNA binding sites, CpG islands and repetitive elements (short interspersed nuclear elements (SINE), long interspersed nuclear elements (LINE), Type II elements and LTR elements). Additionally, all experimental frequencies are compared with the data obtained from a reference set, containing 1 000 000 random integrations ('random set'). Thus, for the first time a tool allowing high-throughput profiling of gene therapy vector insertion sites is available. It provides a basis for large-scale insertion site analyses, which is now urgently needed to discover novel gene therapy vectors with 'safe' insertion profiles.

  7. Lessons from Afar: A Review of www.daisakuikeda.org, Official Website of Daisaku Ikeda

    ERIC Educational Resources Information Center

    Arauz, Luis

    2012-01-01

    Daisaku Ikeda (1928- ) is a Buddhist leader, peace builder, school founder, and poet. His own biography and lifework provide a model for how one can transform adversity into alternative opportunities for some of the most disenfranchised students. Scrutinizing Ikeda's official website (www.daisakuikeda.org) reveals an extensive collection of his…

  8. Delinquent Medical Service Accounts at Brooke Army Medical Center Need Additional Management Oversight

    DTIC Science & Technology

    2014-08-13

    No. DODIG-2014-101 A U G U S T 1 3 , 2 0 1 4 Delinquent Medical Service Accounts at Brooke Army Medical Center Need Additional Management...13 AUG 2014 2. REPORT TYPE 3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE Delinquent Medical Service Accounts at Brooke Army...Results in Brief Delinquent Medical Service Accounts at Brooke Army Medical Center Need Additional Management Oversight Visit us at www.dodig.mil

  9. Site Environmental Report for 2002, Volume 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pauer, Ron

    2003-07-01

    Each year, Ernest Orlando Lawrence Berkeley National Laboratory prepares an integrated report on its environmental programs to satisfy the requirements of United States Department of Energy Order 231.1. The ''Site Environmental Report for 2002'' summarizes Berkeley Lab's compliance with environmental standards and requirements, characterizes environmental management efforts through surveillance and monitoring activities, and highlights significant programs and efforts for calendar year 2002. Throughout this report, Ernest Orlando Lawrence Berkeley National Laboratory is referred to as ''Berkeley Lab,'' ''the Laboratory,'' ''Lawrence Berkeley National Laboratory,'' and ''LBNL.'' The report is separated into two volumes. Volume I contains a general overview of themore » Laboratory, the status of environmental programs, and summarized results from surveillance and monitoring activities. Volume II contains individual data results from the monitoring programs. This year, the ''Site Environmental Report'' was distributed on a CD in PDF format that includes Volume I, Volume II, and related documents. The report is also available on the Web at http://www.lbl.gov/ehs/esg/. The report follows the Laboratory's policy of using the International System of Units (SI), also known as the metric system of measurements. Whenever possible, results are additionally reported using the more conventional (non-SI) system of measurements because this system is referenced by some current regulatory standards and is more familiar to some readers. The tables included at the end of the Glossary are intended to help readers understand the various prefixes used with SI units of measurement and convert these units from one system to the other.« less

  10. Site Environmental Report for 2002, Volume 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pauer, Ron

    2003-07-01

    Each year, Ernest Orlando Lawrence Berkeley National Laboratory prepares an integrated report on its environmental programs to satisfy the requirements of United States Department of Energy Order 231.1. The ''Site Environmental Report for 2002'' summarizes Berkeley Lab's compliance with environmental standards and requirements, characterizes environmental management efforts through surveillance and monitoring activities, and highlights significant programs and efforts for calendar year 2002. Throughout this report, Ernest Orlando Lawrence Berkeley National Laboratory is referred to as ''Berkeley Lab,'' ''the Laboratory,'' ''Lawrence Berkeley National Laboratory,'' and ''LBNL.'' The report is separated into two volumes. Volume I contains a general overview of themore » Laboratory, the status of environmental programs, and summarized results from surveillance and monitoring activities. Volume II contains individual data results from the monitoring programs. This year, the ''Site Environmental Report'' was distributed on a CD in PDF format that includes Volume I, Volume II, and related documents. The report is also available on the Web at http://www.lbl.gov/ehs/esg/. The report follows the Laboratory's policy of using the International System of Units (SI), also known as the metric system of measurements. Whenever possible, results are additionally reported using the more conventional (non-SI) system of measurements because this system is referenced by some current regulatory standards and is more familiar to some readers. The tables included at the end of the Glossary are intended to help readers understand the various prefixes used with SI units of measurement and convert these units from one system to the other.« less

  11. Places to Go: Sakai|http://www.sakaiproject.org/

    ERIC Educational Resources Information Center

    Downes, Stephen

    2006-01-01

    Stephen Downes continues his examination of open source learning management systems (LMSs) with a visit to Sakai's Web site. While Sakai's Web site is not particularly easy to navigate, it provides access to a large community and constellation of related online learning products and initiatives. Visitors can visit discussion forums to ask…

  12. Network Update: WWW Page Writing and Design Helpers.

    ERIC Educational Resources Information Center

    Higgins, Chris

    1997-01-01

    Lists and describes the sites available on the World Wide Web used for Web-based projects for language education. Notes that the number and style of such sites has risen dramatically, reflecting a growing interest among language teaching faculty. Points out that both a program's content and its presentation affect its feasibility as an educational…

  13. Examples from the Greenland-Project - Gentle Remediation Optiones (GROs) on Pb/zn Contaminated Sites

    NASA Astrophysics Data System (ADS)

    Friesl-Hanl, Wolfgang; Kidd, Petra; Siebielec, Grzegorz

    2017-04-01

    The GREENLAND-project brought together "best practice" examples of several field applied gentle remediation techniques (EUFP7-project "Gentle remediation of trace element-contaminated land - GREENLAND; www.greenland-project.eu) with 17 partners from 11 countries. Gentle remediation options (GRO) comprise environmentally friendly technologies that have little or no negative impact on the soil. The main technologies are • phytoextraction • in situ immobilization and • assisted phytostabilization. Mining and processing activities affecting many sites worldwide negatively. The huge amounts of moved and treated materials have led to considerable flows of wastes and emissions. Alongside the many advantages of processed ores to our society, adverse effects in nature and risks for the environment and human health are observed. Three stages of impact of Pb/Zn-ore-treatment on the environment are discussed here: (1) On sites where the ores are mined impacts are the result of crushing, grinding, concentrating activities, and where additionally parts of the installations remain after abandoning the mine, as well as by the massive amounts of remaining deposits or wastes (mine tailings). (2) On sites where smelting and processing takes place, depending on the process (Welz, Doerschel) different waste materials are deposited. The Welz process waste generally contains less Cd and Pb than the Doerschel process waste which additionally shows higher water- extractable metals. (3) On sites close to the emitting source metal contamination can be found in areas for housing, gardening, and agricultural use. Emissions consist mainly from oxides and sulfides (Zn, Cd), sulfates (Zn, Pb, and Cd), chlorides (Pb) and carbonates (Cd). All these wastes and emissions pose potential risks of dispersion of pollutants into the food chain due to erosion (wind, water), leaching and the transfer into feeding stuff and food crops. In-situ treatments have the potential for improving the situation

  14. Lysine acetylation sites prediction using an ensemble of support vector machine classifiers.

    PubMed

    Xu, Yan; Wang, Xiao-Bo; Ding, Jun; Wu, Ling-Yun; Deng, Nai-Yang

    2010-05-07

    Lysine acetylation is an essentially reversible and high regulated post-translational modification which regulates diverse protein properties. Experimental identification of acetylation sites is laborious and expensive. Hence, there is significant interest in the development of computational methods for reliable prediction of acetylation sites from amino acid sequences. In this paper we use an ensemble of support vector machine classifiers to perform this work. The experimentally determined acetylation lysine sites are extracted from Swiss-Prot database and scientific literatures. Experiment results show that an ensemble of support vector machine classifiers outperforms single support vector machine classifier and other computational methods such as PAIL and LysAcet on the problem of predicting acetylation lysine sites. The resulting method has been implemented in EnsemblePail, a web server for lysine acetylation sites prediction available at http://www.aporc.org/EnsemblePail/. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  15. Factors influencing clicking of banner ads on the WWW.

    PubMed

    Cho, Chang-Hoan

    2003-04-01

    This paper explores various factors influencing the clicking of banner ads on the WWW. The study indicates that several important variables affect the clicking of banner ads: (1) level of product involvement, (2) congruency between the content of a vehicle and the product category of a banner ad, (3) attitude toward the vehicle, and (4) overall attitude toward web advertising. For methodology, this study employed a between-group experimental design and measured real click-through rates with the aid of an online data collection technology called FileMaker Pro. Results of logistic regressions show that people are more likely to click banner ads if they are highly involved with products, perceive high synergy between web pages and ads, have a favorable attitude toward a vehicle, or have a favorable attitude toward web advertising in general. A total of 756 subjects participated in this research.

  16. The Ensembl Web Site: Mechanics of a Genome Browser

    PubMed Central

    Stalker, James; Gibbins, Brian; Meidl, Patrick; Smith, James; Spooner, William; Hotz, Hans-Rudolf; Cox, Antony V.

    2004-01-01

    The Ensembl Web site (http://www.ensembl.org/) is the principal user interface to the data of the Ensembl project, and currently serves >500,000 pages (∼2.5 million hits) per week, providing access to >80 GB (gigabyte) of data to users in more than 80 countries. Built atop an open-source platform comprising Apache/mod_perl and the MySQL relational database management system, it is modular, extensible, and freely available. It is being actively reused and extended in several different projects, and has been downloaded and installed in companies and academic institutions worldwide. Here, we describe some of the technical features of the site, with particular reference to its dynamic configuration that enables it to handle disparate data from multiple species. PMID:15123591

  17. The Ensembl Web site: mechanics of a genome browser.

    PubMed

    Stalker, James; Gibbins, Brian; Meidl, Patrick; Smith, James; Spooner, William; Hotz, Hans-Rudolf; Cox, Antony V

    2004-05-01

    The Ensembl Web site (http://www.ensembl.org/) is the principal user interface to the data of the Ensembl project, and currently serves >500,000 pages (approximately 2.5 million hits) per week, providing access to >80 GB (gigabyte) of data to users in more than 80 countries. Built atop an open-source platform comprising Apache/mod_perl and the MySQL relational database management system, it is modular, extensible, and freely available. It is being actively reused and extended in several different projects, and has been downloaded and installed in companies and academic institutions worldwide. Here, we describe some of the technical features of the site, with particular reference to its dynamic configuration that enables it to handle disparate data from multiple species.

  18. 14 CFR 11.63 - How and to whom do I submit my petition for rulemaking or petition for exemption?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ..., submit your petition for rulemaking or exemption to FAA through the Internet at http://www.regulations.gov, the Federal Docket Management System Web site. For additional instructions, you may visit http... 20590 or by electronic submission to this Internet address: http://www.regulations.gov. (c) The FAA may...

  19. MED40/472: A WWW Multimedia Textbook of Internal Propedeutics

    PubMed Central

    Zelenková, J; Vejvalka, J; Holá, D; Segethová, J

    1999-01-01

    Introduction Traditional ways of teaching techniques of physical examinations in the first clinical courses are rather demanding in terms of teacher involvement and a pool of patients suitable for demonstrations. For a long time, various audio-visual tools have been used to save teachers' and students' time and patients' patience. The modern technology of WWW publishing of multimedia allows good access to such teaching materials - and there already exist several collections of heart sounds, breath sounds etc. The aim of our project is to design and set up a comprehensive multimedia textbook of internal propedeutics that would present various physiological and pathological findings (auscultation, inspection, basic imaging) in the context of diagnostic patient investigation - the status praesens - as it is taught in the first clinical courses. Methods Unlike classical textbooks, hypertext presentation allows to ogranize the material into several structures - reflecting various approaches: systemic (digestive, cardiovascular etc.) approach, nosological, differential diagnoses, etc. To identify and implement the various useful approaches is the most difficult part of the task. The accompanying illustrative material is being prepared with the use of modern technologies - digital camera, scanner, video-camera and digitizer, digital audio recording, etc. Results In the first year of the project, the skeleton of the multimedia presentation is being constructed - corresponding to the various approaches to the subject. Concurrently, suitable illustrative material is being gathered from cases of the Internal Clinic. Various existing WWW presentations dealing with heart and breath sounds and other relevant investigations have been searched and listed. Discussion Experience and feedback from other projects of this type confirm that a rather elaborate logical and technical construction of multimedia textbooks is rewarded by a good acceptance by both students and teachers. Good

  20. Culture differences in design of portal sites.

    PubMed

    Fang, Xiaowen; Rau, Pei-Luen Patrick

    2003-01-15

    Two experiments were carried out to examine the effects of cultural differences between the Chinese and the US people on the perceived usability and search performance of World Wide Web (WWW) portal sites. Chinese users in Taiwan and US users in Chicago were recruited to perform searching tasks on two versions of Yahoo! portal site: the standard Yahoo! and Yahoo! Chinese. The layout of Yahoo! Chinese is the same as the layout of Yahoo!, and categories on Yahoo! Chinese have been translated from its US counterpart. A special browser was programmed to record all the keystroke data and participants were asked to fill out a satisfaction questionnaire after finishing the tasks. Significant differences of satisfaction and steps to perform some tasks were found between the two groups. The experiment results also provided more detailed insights into the cultural differences between the Chinese and the US users.

  1. Modification of the Creator recombination system for proteomics applications--improved expression by addition of splice sites.

    PubMed

    Colwill, Karen; Wells, Clark D; Elder, Kelly; Goudreault, Marilyn; Hersi, Kadija; Kulkarni, Sarang; Hardy, W Rod; Pawson, Tony; Morin, Gregg B

    2006-03-06

    Recombinational systems have been developed to rapidly shuttle Open Reading Frames (ORFs) into multiple expression vectors in order to analyze the large number of cDNAs available in the post-genomic era. In the Creator system, an ORF introduced into a donor vector can be transferred with Cre recombinase to a library of acceptor vectors optimized for different applications. Usability of the Creator system is impacted by the ability to easily manipulate DNA, the number of acceptor vectors for downstream applications, and the level of protein expression from Creator vectors. To date, we have developed over 20 novel acceptor vectors that employ a variety of promoters and epitope tags commonly employed for proteomics applications and gene function analysis. We also made several enhancements to the donor vectors including addition of different multiple cloning sites to allow shuttling from pre-existing vectors and introduction of the lacZ alpha reporter gene to allow for selection. Importantly, in order to ameliorate any effects on protein expression of the loxP site between a 5' tag and ORF, we introduced a splicing event into our expression vectors. The message produced from the resulting 'Creator Splice' vector undergoes splicing in mammalian systems to remove the loxP site. Upon analysis of our Creator Splice constructs, we discovered that protein expression levels were also significantly increased. The development of new donor and acceptor vectors has increased versatility during the cloning process and made this system compatible with a wider variety of downstream applications. The modifications introduced in our Creator Splice system were designed to remove extraneous sequences due to recombination but also aided in downstream analysis by increasing protein expression levels. As a result, we can now employ epitope tags that are detected less efficiently and reduce our assay scale to allow for higher throughput. The Creator Splice system appears to be an extremely

  2. 2013 Annual Site Inspection and Monitoring Report for Uranium Mill Tailings Radiation Control Act Title I Disposal Sites

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    This report, in fulfillment of a license requirement, presents the results of long-term surveillance and maintenance activities conducted by the U.S. Department of Energy (DOE) Office of Legacy Management (LM) in 2013 at 19 uranium mill tailings disposal sites established under Title I of the Uranium Mill Tailings Radiation Control Act (UMTRCA) of 1978.1 These activities verified that the UMTRCA Title I disposal sites remain in compliance with license requirements. DOE operates 18 UMTRCA Title I sites under a general license granted by the U.S. Nuclear Regulatory Commission (NRC) in accordance with Title 10 Code of Federal Regulations Part 40.27more » (10 CFR 40.27). As required under the general license, a long-term surveillance plan (LTSP) for each site was prepared by DOE and accepted by NRC. The Grand Junction, Colorado, Disposal Site, one of the 19 Title I sites, will not be included under the general license until the open, operating portion of the cell is closed. The open portion will be closed either when it is filled or in 2023. This site is inspected in accordance with an interim LTSP. Long-term surveillance and maintenance services for these disposal sites include inspecting and maintaining the sites; monitoring environmental media and institutional controls; conducting any necessary corrective actions; and performing administrative, records, stakeholder relations, and other regulatory stewardship functions. Annual site inspections and monitoring are conducted in accordance with site-specific LTSPs and procedures established by DOE to comply with license requirements. Each site inspection is performed to verify the integrity of visible features at the site; to identify changes or new conditions that may affect the long-term performance of the site; and to determine the need, if any, for maintenance, follow-up or contingency inspections, or corrective action in accordance with the LTSP. LTSPs and site compliance reports are available on the Internet at

  3. 78 FR 13855 - Notice of March 14 Advisory Committee on Voluntary Foreign Aid Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-01

    ... members and USAID leadership, and an open Q&A. A draft agenda, room location, and additional information will be forthcoming on the ACVFA Web site at http://www.usaid.gov/who-we-are/organization/advisory... register online at http://www.usaid.gov/who-we-are/organization/advisory-committee/get-involved . FOR...

  4. Nickel binding to NikA: an additional binding site reconciles spectroscopy, calorimetry and crystallography.

    PubMed

    Addy, Christine; Ohara, Masato; Kawai, Fumihiro; Kidera, Akinori; Ikeguchi, Mitsunori; Fuchigami, Sotaro; Osawa, Masanori; Shimada, Ichio; Park, Sam-Yong; Tame, Jeremy R H; Heddle, Jonathan G

    2007-02-01

    Intracellular nickel is required by Escherichia coli as a cofactor for a number of enzymes and is necessary for anaerobic respiration. However, high concentrations of nickel are toxic, so both import and export systems have evolved to control the cellular level of the metal. The nik operon in E. coli encodes a nickel-uptake system that includes the periplasmic nickel-binding protein NikA. The crystal structures of wild-type NikA both bound to nickel and in the apo form have been solved previously. The liganded structure appeared to show an unusual interaction between the nickel and the protein in which no direct bonds are formed. The highly unusual nickel coordination suggested by the crystal structure contrasted strongly with earlier X-ray spectroscopic studies. The known nickel-binding site has been probed by extensive mutagenesis and isothermal titration calorimetry and it has been found that even large numbers of disruptive mutations appear to have little effect on the nickel affinity. The crystal structure of a binding-site mutant with nickel bound has been solved and it is found that nickel is bound to two histidine residues at a position distant from the previously characterized binding site. This novel site immediately resolves the conflict between the crystal structures and other biophysical analyses. The physiological relevance of the two binding sites is discussed.

  5. Evidence of global demand for medication abortion information An analysis of www.medicationabortion.com

    PubMed Central

    Foster, Angel M.; Wynn, L. L.; Trussell, James

    2013-01-01

    Introduction The worldwide expansion of the Internet offers an important modality of disseminating medically accurate information about medication abortion. We chronicle the story of www.medicationabortion.com, an English-, Spanish-, Arabic-, and French-language website dedicated to three early abortion regimens. Methods We evaluated the website use patterns from 2005 through 2009. We also conducted a content and thematic analysis of 1,910 emails submitted during this period. Results The website experienced steady growth in use. In 2009, it received 35,000 visits each month from more than 20,000 unique visitors and was accessed by users in 208 countries and territories. More than half of all users accessed the website from a country in which abortion is legally restricted. Users from more than 40 countries sent emails with individual questions. Women often wrote in extraordinary detail about the circumstances of their pregnancies and attempts to obtain an abortion. These emails also reflect considerable demand for information about the use of misoprostol for self-induction. Conclusion The use patterns of www.medicationabortion.com indicate that there is significant demand for online information about abortion, and the findings suggest future priorities for research, collaboration, and educational outreach. PMID:24360644

  6. JEA's Code of Ethics for Advisers; and Sites for Additional Ethics Information.

    ERIC Educational Resources Information Center

    Bowen, John

    1997-01-01

    Lists general principles that media advisers should follow, the 12 points agreed upon as the Journalism Education Association's (JEA) Code of Ethics for Advisers, and a list of Web sites that deal with journalism ethics. (PA)

  7. Installing a Local Copy of the Reactome Web Site and Knowledgebase

    PubMed Central

    McKay, Sheldon J; Weiser, Joel

    2015-01-01

    The Reactome project builds, maintains, and publishes a knowledgebase of biological pathways. The information in the knowledgebase is gathered from the experts in the field, peer reviewed, and edited by Reactome editorial staff and then published to the Reactome Web site, http://www.reactome.org (see UNIT 8.7; Croft et al., 2013). The Reactome software is open source and builds on top of other open-source or freely available software. Reactome data and code can be freely downloaded in its entirety and the Web site installed locally. This allows for more flexible interrogation of the data and also makes it possible to add one’s own information to the knowledgebase. PMID:26087747

  8. Adding Automation and Decision Support Capabilities at the Reagan Test Site

    DTIC Science & Technology

    2016-04-04

    Tech Notes www.ll.mit.edu May 2016 The U.S. Army’s Reagan Test Site (RTS), approximately 2300 miles west southwest of Hawaii on the Kwajalein Atoll...in the Marshall Islands , is ideal for missile and interceptor testing because of its distance from populous areas and its open-ocean line from...by three components: • The event processor determines the high-level state of the mission by moni- toring events such as information from uprange

  9. Effect of and satisfaction with www.elearnSCI.org for training of nurse students: a submodule pilot study.

    PubMed

    Liu, N; Li, X W; Zhou, M W; Krassioukov, A V; Biering-Sørensen, F

    2014-10-01

    Interventional training session. To investigate the effect and satisfaction with didactic training using printed text of a submodule of www.elearnSCI.org for nurse students and to assess the answers of each question. A Peking University teaching hospital. Twenty-eight nurse students in two groups (14 in each) were involved. Only group A received a translated print-out of the slides from the 'Nursing management' submodule in www.elearnSCI.org for 1-h self-study before the class. At the beginning of class, both groups were tested using the self assessment questions. Then, a lecture according to the content of this submodule was carried out and afterwards both groups answered the self assessment questions again. Finally, both groups filled in a training course satisfaction questionnaire. At the beginning of the class, the mean score (max 9) of the self assessment in group A was 7.1 ± 1.1, which was significantly higher than that in group B (4.9 ± 1.7, P = 0.001). After the lecture, the mean score of the self assessment in group A had insignificantly increased to 7.4 ± 1.3, whereas in group B it increased significantly to 6.9 ± 0.8 (P < 0.001). The mean score (max 50) of the training course satisfaction questionnaire was 42.8 ± 5.2. Sixty-four percentage of the students indicated that they were very satisfied (overall score ⩾ 42) with the training and no students were unsatisfied (overall score < 30). Self-study and lecture presentation are effective methods for training the content of www.elearnSCI.org to nurse students. The training satisfaction of this submodule within the www.elearnSCI.org is favorable.

  10. Addition of Sulfometuron Methyl to Fall Site Preparation Tank Mixes Improves Herbaceous Weed Control

    Treesearch

    A.W. Ezell

    2002-01-01

    A total of 12 herbicide treatments were applied to a recently harvested forest site in Winston County, MS. All treatments were representative of forest site preparation tank mixtures and were applied early September, 1999. Three ounces of Oust7 were included in two of the tank mixes, and 19 ounces of Oustar7 were included in two of the mixes. All treatments were...

  11. Effect of Sn addition on glassy Si-Te bulk sample

    NASA Astrophysics Data System (ADS)

    Babanna, Jagannatha K.; Roy, Diptoshi; Varma, Sreevidya G.; Asokan, Sundarrajan; Das, Chandasree

    2018-05-01

    Bulk Si20Te79Sn1 glass is prepared by melt-quenching method, amorphous nature of the as-quenched glass is confirmed by XRD. I-V characteristics reveals that Si20Te79Sn1 bulk sample exhibits threshold type electrical switching behavior. The thermal parameters such as crystallization temperature, glass transition temperature are obtained using differential scanning calorimetry. The crystalline peak study of the sample annealed at crystallization temperature for 2 hr shows that the Sn atom interact with Si or Te but do not interact with the Si-Te matrix in a greater extent and it forms a separate phase network individually.

  12. Stardial -- an autonomous astronomical camera on the WWW

    NASA Astrophysics Data System (ADS)

    McCullough, P. R.; Thakkar, U.

    1997-05-01

    The use of an autonomous electronic camera, called ``Stardial,'' for undergraduate instruction is described. Stardial delivers images of the night sky nearly in real-time to the world wide web (www.astro.uiuc.edu/stardial/). The remote instrumentation of Stardial is robust, inexpensive, and accomodates many students asynchronously with respect to the instructor(s). The guiding philosophy of the curriculum is to provide students with authentic astronomical data so that they may learn about science by doing it themselves on the internet. Students respond favorably to the opportunity to learn from their own experiences with genuine data, complete with its irregularities and its surprises. Perhaps surprisingly, 9 of 10 self-selected student volunteers in our pilot project were female. Stardial's instrumentation is similar to that of Gaustad et al., and to that of Richmond, Droege, et al. (both at this same meeting). Stardial has benefitted from contributions from students, especially Lawrence Tan, Troy Klyber, Jim Pulokas, Jim Waldemer, and Diana Lopez, and from a number of professionals, especially G.T. Becker, Mike Newberry, John Dolby, Tom Droege, Bob Mutel, Mike Richmond, John Thorstensen, and Rick White. Stardial is funded by the University of Illinois, primarily from the office of the Vice President for Academic Affairs. We welcome participation from amateur astronomers and other educators.

  13. Additional Analysis of the ESTCP Discrimination Study Data at Camp Sibert, Alabama. Project 200504: Practical Discrimination Strategies for Application to Live Sites

    DTIC Science & Technology

    2008-10-20

    Dr. Stephen Billings Dr. Leonard Pasion Sky Research, Inc) Laurens Beran UBC-GIF Approved for public release; distribution...Sites 5. FUNDING NUMBERS Contract # W912HQ-05-C-0018 6. AUTHOR(S) Dr. Stephen Billings, Dr. Leonard Pasion (Sky Research, Inc.) Laurens Beran...representative of the test datasets. ESTCP MM-0504: Additional Analysis of Camp Sibert Data Sky Research Inc October 2008 References [1] L.R. Pasion , N

  14. [Evaluation of an internet site on evidence-based medicine].

    PubMed

    Mathys, J; Steurer, J

    2000-10-19

    The present study evaluated a Swiss internet provider of Evidence-based Medicine (EBM) with regard to its utilization and function for medical practitioners. The internet provider under study (www.evimed.ch) primarily provides abstracts of original articles relevant to medical practice that are presented according to the criteria of EBM and includes information about EBM itself. In March 1999 a survey was conducted to better appraise the benefits gained from the information provided from the website visitors' point of view. Around 400 persons who had entered their names in the homepage guest book were informed about the survey by e-mail. A total of 167 questionnaires were filled in online, which is equivalent to the reply rate of close to 42%. The majority of the replies (63.5%) were from private-practice physicians, 22.2% from hospital-based physicians. The average age ranged between 40 and 49 years. 67.7% of the 167 respondents had internet access at their workplace, 72.5% had private internet access. For their own practical work, 61.1% of the respondents rated the information provided by www.evimed.ch as generally useful. The clinical relevance of the studies presented in the Journal Club was rated as good by 55.7% and as very good by 26.9%. The reliability of the information provided was rated as good by 56.3% and as very good by 35.3%. The majority regarded the following homepage sites as personally important: Journal Club (55.7%), articles about EBM (46.1%), MEDLINE access (37.7%) and article citations/links (41.3%). The homepage was visited at an average frequency of 1-3 times a month. 50.3% preferred electronic media (40.1% using various internet providers, 10.2% www.evimed.ch) and 44.3% preferred print media to search for specialist information on a specific medical subject. With regard to new medical findings, 44.9% of the respondents stated that they used print media, 17.4% the www.evimed.ch homepage and 28.7% other internet sources as their primary

  15. Regulation of E2s: A Role for Additional Ubiquitin Binding Sites?

    PubMed

    Middleton, Adam J; Wright, Joshua D; Day, Catherine L

    2017-11-10

    Attachment of ubiquitin to proteins relies on a sophisticated enzyme cascade that is tightly regulated. The machinery of ubiquitylation responds to a range of signals, which remarkably includes ubiquitin itself. Thus, ubiquitin is not only the central player in the ubiquitylation cascade but also a key regulator. The ubiquitin E3 ligases provide specificity to the cascade and often bind the substrate, while the ubiquitin-conjugating enzymes (E2s) have a pivotal role in determining chain linkage and length. Interaction of ubiquitin with the E2 is important for activity, but the weak nature of these contacts has made them hard to identify and study. By reviewing available crystal structures, we identify putative ubiquitin binding sites on E2s, which may enhance E2 processivity and the assembly of chains of a defined linkage. The implications of these new sites are discussed in the context of known E2-ubiquitin interactions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. 31 CFR Appendix A to Part 560 - Persons Determined to be the Government of Iran, as defined in § 560.304 of This Part

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...), available on OFAC's Web site. New names of persons determined to be the Government of Iran and changes to...'s Web site. Appendix A to Part 560 will be republished annually. This document and additional information concerning OFAC are available from OFAC's Web site (http://www.treas.gov/ofac). Certain general...

  17. WWW.LCACCESS - GLOBAL DIRECTORY OF LCI RESOURCES

    EPA Science Inventory

    LCAccess is a USEPA sponsored web-site intended to promote the use of Life Cycle Assessment in business decision-making by facilitating access to data sources useful in developing a life cycle inventory (OCI). While LCAccess will not itself contain data, it will be a searchable g...

  18. WWW.LCACCESS -- GLOBAL DIRECTORY OF LCI RESOURCES

    EPA Science Inventory

    LCAccess is a USEPA sponsored web-site intended to promote the use of Life Cycle Assessments in business decision-making by facilitating access to data sources useful in developing a life cycle inventory (LCI). While LCAccess will not itself contain data, it will be a searchable...

  19. Modification of the Creator recombination system for proteomics applications – improved expression by addition of splice sites

    PubMed Central

    Colwill, Karen; Wells, Clark D; Elder, Kelly; Goudreault, Marilyn; Hersi, Kadija; Kulkarni, Sarang; Hardy, W Rod; Pawson, Tony; Morin, Gregg B

    2006-01-01

    Background Recombinational systems have been developed to rapidly shuttle Open Reading Frames (ORFs) into multiple expression vectors in order to analyze the large number of cDNAs available in the post-genomic era. In the Creator system, an ORF introduced into a donor vector can be transferred with Cre recombinase to a library of acceptor vectors optimized for different applications. Usability of the Creator system is impacted by the ability to easily manipulate DNA, the number of acceptor vectors for downstream applications, and the level of protein expression from Creator vectors. Results To date, we have developed over 20 novel acceptor vectors that employ a variety of promoters and epitope tags commonly employed for proteomics applications and gene function analysis. We also made several enhancements to the donor vectors including addition of different multiple cloning sites to allow shuttling from pre-existing vectors and introduction of the lacZ alpha reporter gene to allow for selection. Importantly, in order to ameliorate any effects on protein expression of the loxP site between a 5' tag and ORF, we introduced a splicing event into our expression vectors. The message produced from the resulting 'Creator Splice' vector undergoes splicing in mammalian systems to remove the loxP site. Upon analysis of our Creator Splice constructs, we discovered that protein expression levels were also significantly increased. Conclusion The development of new donor and acceptor vectors has increased versatility during the cloning process and made this system compatible with a wider variety of downstream applications. The modifications introduced in our Creator Splice system were designed to remove extraneous sequences due to recombination but also aided in downstream analysis by increasing protein expression levels. As a result, we can now employ epitope tags that are detected less efficiently and reduce our assay scale to allow for higher throughput. The Creator Splice

  20. Active Site Detection by Spatial Conformity and Electrostatic Analysis—Unravelling a Proteolytic Function in Shrimp Alkaline Phosphatase

    PubMed Central

    Chakraborty, Sandeep; Minda, Renu; Salaye, Lipika; Bhattacharjee, Swapan K.; Rao, Basuthkar J.

    2011-01-01

    Computational methods are increasingly gaining importance as an aid in identifying active sites. Mostly these methods tend to have structural information that supplement sequence conservation based analyses. Development of tools that compute electrostatic potentials has further improved our ability to better characterize the active site residues in proteins. We have described a computational methodology for detecting active sites based on structural and electrostatic conformity - C ata L ytic A ctive S ite P rediction (CLASP). In our pipelined model, physical 3D signature of any particular enzymatic function as defined by its active sites is used to obtain spatially congruent matches. While previous work has revealed that catalytic residues have large pKa deviations from standard values, we show that for a given enzymatic activity, electrostatic potential difference (PD) between analogous residue pairs in an active site taken from different proteins of the same family are similar. False positives in spatially congruent matches are further pruned by PD analysis where cognate pairs with large deviations are rejected. We first present the results of active site prediction by CLASP for two enzymatic activities - β-lactamases and serine proteases, two of the most extensively investigated enzymes. The results of CLASP analysis on motifs extracted from Catalytic Site Atlas (CSA) are also presented in order to demonstrate its ability to accurately classify any protein, putative or otherwise, with known structure. The source code and database is made available at www.sanchak.com/clasp/. Subsequently, we probed alkaline phosphatases (AP), one of the well known promiscuous enzymes, for additional activities. Such a search has led us to predict a hitherto unknown function of shrimp alkaline phosphatase (SAP), where the protein acts as a protease. Finally, we present experimental evidence of the prediction by CLASP by showing that SAP indeed has protease activity in vitro

  1. Research on the quarantine pathogen Phytophthora ramorum at the National Ornamentals Research Site at Dominican University of California

    Treesearch

    Wolfgang Schweigkofler; Kathleen Kosta; Tomas Pastalka; Vernon Huffman; Supriya Sharma; Karen Suslow

    2017-01-01

    The National Ornamentals Research Site at Dominican University of California (NORS-DUC) was founded in the year 2009 by a Farm Bill grant to study Phytophthora ramorum in a sophisticated research nursery that reflects an authentic commercial nursery setting (www.dominican.edu/norsduc). NORS-DUC goals are to develop practical solutions for...

  2. 76 FR 8799 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Approving a Proposed Rule Change To List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-15

    ... will provide Web site disclosure of portfolio holdings daily and will include, as applicable, the names... same time, and the Web site for the Fund ( http://www.teucriumoilfund.com ) and/or the Exchange will... addition, the Web site disclosure of the portfolio composition of the Fund will occur at the same time as...

  3. Understanding and using organizational politics, Part Two.

    PubMed

    Pickett, Ronald B; Kennedy, Marilyn Moats

    2004-01-01

    Politics is a fact of life in industry, academia, the military, religion, and even health care. Remember these five major ideas: 1. Politics exists in organizations. 2. Politics can be understood. 3. Politics can be managed. 4. Denial won't make politics go away. 5. You can become a better and more ethical organizational politician. Try these web sites for more information: http://www.bredemeyer.com/pdf_files/PoliticsCompetency.PDF. The political competency model presented here is for architects; however, it provides some interesting insights that you may find helpful. http://www.andersonconsulting.com/doopinto.htm. This web site has "The Dysfunctional Office and Organizational Politics Scale" that you can take online. http://www.politicalsavvy.com/. In addition to a newsletter, this web site lets you test your political savvy IQ and allows you to read further about politics in organizations.

  4. Pinellas County, Florida Site Environmental Restoration Project Semiannual Progress Report for the 4.5 Acre Site June through November 2016 January 2017

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Survochak, Scott; Daniel, Joe

    This Pinellas County, Florida, Site Environmental Restoration Project Semiannual Progress Report for the 4.5 Acre Site describes environmental restoration activities for the 4.5 Acre Site located in Pinellas County, Largo, Florida (Figure 1). The former U.S. Department of Energy (DOE) Pinellas Plant facility consisted of the 4.5 Acre Site and what is now the STAR Center (Young - Rainey Science, Technology, and Research Center). Both the 4.5 Acre Site and the STAR Center are part of the overall Pinellas County, Florida, Site (Figure 2). The 4.5 Acre Site is located immediately northwest of the STAR Center, in the northeast quartermore » of Section 13, Township 30 South, Range 15 East. DOE owned this parcel from 1957 to 1972, at which time it was sold to a private landowner. During the period of DOE ownership, the property was used for the disposal of drums of waste resins and solvents. As a result of this practice, the surficial aquifer was impacted by volatile organic compounds (VOCs)—trichloroethene (TCE), cis-1,2-dichloroethene (cDCE), trans-1,2-dichloroethene (tDCE), vinyl chloride (VC), and benzene. Detailed background information for the site is contained in the Long-Term Surveillance and Maintenance Plan for the Pinellas Site (DOE 2016). That document and other site-related documents can be accessed at this website: http://www.lm.doe.gov/Pinellas/Sites.aspx. Recent remediation activities consist of the injection of emulsified soybean oil and the microorganism Dehalococcoides mccartyi (formerly known as Dehalococcoides ethenogenes) into the subsurface in February 2010 and again in July 2013 to enhance contaminant biodegradation (hereafter described as bioinjection). Monitoring the performance of these actions, in the form of monitoring well sampling, is ongoing.« less

  5. 78 FR 56944 - Sunshine Act Meetings; National Science Board

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-16

    ... Web site ( http://www.nsf.gov/nsb/notices/ ) for additional information and schedule updates, or...: ``The Future of Advanced Cyberinfrastructure for Science and Engineering, Research and Education...

  6. 76 FR 27315 - EPA Science Advisory Board Staff Invitation to a Session on Public Involvement in EPA Advisory...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... and SAB Three inter-related public access Web sites ( http://www.epa.gov/advisorycouncilcaa , http...) ``Recent Happenings'' and ``Recent Additions'' sections and related ``really simple syndication'' (RSS...

  7. Transcription factor HIF1A: downstream targets, associated pathways, polymorphic hypoxia response element (HRE) sites, and initiative for standardization of reporting in scientific literature.

    PubMed

    Slemc, Lucija; Kunej, Tanja

    2016-11-01

    Hypoxia-inducible factor-1α (HIF-1α) has crucial role in adapting cells to hypoxia through expression regulation of many genes. Identification of HIF-1α target genes (HIF-1α-TGs) is important for understanding the adapting mechanism. The aim of the present study was to collect known HIF-1α-TGs and identify their associated pathways. Targets and associated genomics data were retrieved using PubMed, WoS ( http://apps.webofknowledge.com/ ), HGNC ( http://www.genenames.org/ ), NCBI ( http://www.ncbi.nlm.nih.gov/ ), Ensemblv.84 ( http://www.ensembl.org/index.html ), DAVID Bioinformatics Resources ( https://david.ncifcrf.gov /), and Disease Ontology database ( http://disease-ontology.org/ ). From 51 papers, we collected 98 HIF-1α TGs found to be associated with 20 pathways, including metabolism of carbohydrates and pathways in cancer. Reanalysis of genomic coordinates of published HREs (hypoxia response elements) revealed six polymorphisms within HRE sites (HRE-SNPs): ABCG2, ACE, CA9, and CP. Due to large heterogeneity of results presentation in scientific literature, we also propose a first step towards reporting standardization of HIF-1α-target interactions consisting of ten relevant data types. Suggested minimal checklist for reporting will enable faster development of a complete catalog of HIF-1α-TGs, data sharing, bioinformatics analyses, and setting novel more targeted hypotheses. The proposed format for data standardization is not yet complete but presents a baseline for further optimization of the protocol with additional details, for example, regarding the experimental validation.

  8. Effects of nutrient and lime additions in mine site rehabilitation strategies on the accumulation of antimony and arsenic by native Australian plants.

    PubMed

    Wilson, Susan C; Leech, Calvin D; Butler, Leo; Lisle, Leanne; Ashley, Paul M; Lockwood, Peter V

    2013-10-15

    The effects of nutrient and lime additions on antimony (Sb) and arsenic (As) accumulation by native Australian and naturalised plants growing in two contaminated mine site soils (2,735 mg kg(-1) and 4,517 mg kg(-1) Sb; 826 mg kg(-1) and 1606 As mgkg(-1)) was investigated using a glasshouse pot experiment. The results indicated an increase in soil solution concentrations with nutrient addition in both soils and also with nutrient+lime addition for Sb in one soil. Metalloid concentrations in plant roots were significantly greater than concentrations in above ground plant parts. The metalloid transfer to above ground plant parts from the roots and from the soil was, however, low (ratio of leaf concentration/soil concentration≪1) for all species studied. Eucalyptus michaeliana was the most successful at colonisation with lowest metalloid transfer to above ground plant parts. Addition of nutrients and nutrients+lime to soils, in general, increased plant metalloid accumulation. Relative As accumulation was greater than that of Sb. All the plant species studied were suitable for consideration in the mine soil phytostabilisation strategies but lime additions should be limited and longer term trials also recommended. Copyright © 2013 Elsevier B.V. All rights reserved.

  9. SigniSite: Identification of residue-level genotype-phenotype correlations in protein multiple sequence alignments.

    PubMed

    Jessen, Leon Eyrich; Hoof, Ilka; Lund, Ole; Nielsen, Morten

    2013-07-01

    Identifying which mutation(s) within a given genotype is responsible for an observable phenotype is important in many aspects of molecular biology. Here, we present SigniSite, an online application for subgroup-free residue-level genotype-phenotype correlation. In contrast to similar methods, SigniSite does not require any pre-definition of subgroups or binary classification. Input is a set of protein sequences where each sequence has an associated real number, quantifying a given phenotype. SigniSite will then identify which amino acid residues are significantly associated with the data set phenotype. As output, SigniSite displays a sequence logo, depicting the strength of the phenotype association of each residue and a heat-map identifying 'hot' or 'cold' regions. SigniSite was benchmarked against SPEER, a state-of-the-art method for the prediction of specificity determining positions (SDP) using a set of human immunodeficiency virus protease-inhibitor genotype-phenotype data and corresponding resistance mutation scores from the Stanford University HIV Drug Resistance Database, and a data set of protein families with experimentally annotated SDPs. For both data sets, SigniSite was found to outperform SPEER. SigniSite is available at: http://www.cbs.dtu.dk/services/SigniSite/.

  10. Nevada National Security Site Environmental Report 2010

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    C. Wills, ed.

    2011-09-13

    This NNSSER was prepared to satisfy DOE Order DOE O 231.1B, “Environment, Safety and Health Reporting.” Its purpose is to (1) report compliance status with environmental standards and requirements, (2) present results of environmental monitoring of radiological and nonradiological effluents, (3) report estimated radiological doses to the public from releases of radioactive material, (4) summarize environmental incidents of noncompliance and actions taken in response to them, (5) describe the NNSA/NSO Environmental Management System and characterize its performance, and (6) highlight significant environmental programs and efforts. This NNSSER summarizes data and compliance status for calendar year 2010 at the Nevada Nationalmore » Security Site (NNSS) (formerly the Nevada Test Site) and its two support facilities, the North Las Vegas Facility (NLVF) and the Remote Sensing Laboratory–Nellis (RSL-Nellis). It also addresses environmental restoration (ER) projects conducted at the Tonopah Test Range (TTR). Through a Memorandum of Agreement, NNSA/NSO is responsible for the oversight of TTR ER projects, and the Sandia Site Office of NNSA (NNSA/SSO) has oversight of all other TTR activities. NNSA/SSO produces the TTR annual environmental report available at http://www.sandia.gov/news/publications/environmental/index.html.« less

  11. Onco-Regulon: an integrated database and software suite for site specific targeting of transcription factors of cancer genes

    PubMed Central

    Tomar, Navneet; Mishra, Akhilesh; Mrinal, Nirotpal; Jayaram, B.

    2016-01-01

    Transcription factors (TFs) bind at multiple sites in the genome and regulate expression of many genes. Regulating TF binding in a gene specific manner remains a formidable challenge in drug discovery because the same binding motif may be present at multiple locations in the genome. Here, we present Onco-Regulon (http://www.scfbio-iitd.res.in/software/onco/NavSite/index.htm), an integrated database of regulatory motifs of cancer genes clubbed with Unique Sequence-Predictor (USP) a software suite that identifies unique sequences for each of these regulatory DNA motifs at the specified position in the genome. USP works by extending a given DNA motif, in 5′→3′, 3′ →5′ or both directions by adding one nucleotide at each step, and calculates the frequency of each extended motif in the genome by Frequency Counter programme. This step is iterated till the frequency of the extended motif becomes unity in the genome. Thus, for each given motif, we get three possible unique sequences. Closest Sequence Finder program predicts off-target drug binding in the genome. Inclusion of DNA-Protein structural information further makes Onco-Regulon a highly informative repository for gene specific drug development. We believe that Onco-Regulon will help researchers to design drugs which will bind to an exclusive site in the genome with no off-target effects, theoretically. Database URL: http://www.scfbio-iitd.res.in/software/onco/NavSite/index.htm PMID:27515825

  12. MRSA – ‘Bug-Bear’ of a Surgical Practice: Reducing the Incidence of MRSA Surgical Site Infections

    PubMed Central

    Guyot, Andrea; Layer, Graham

    2006-01-01

    Adverse publicity (the ‘superbug') has demonstrated that the problem of MRSA (methicillin-resistant Staphylococcus aureus) is prevalent in many of the country's most prestigious hospitals. The results of the mandatory UK Department of Health (DH) surveillance for early surgical site infections in orthopaedic surgery (SSIS) have been published recently for the period April 2004 to March 2005 when 41,242 operations were studied (www.dh.gov.uk/PublicationsAndStatistics/Publications/PublicationsStatistic> 28 October 2005). Infection rates were generally and gratifyingly low but 48% of surgical site infections were caused by Staph. aureus and of those 68% were MRSA. The following article will discuss the aetiology and prevention of MRSA surgical site infection. PMID:16551425

  13. 2006 SITE ENVIRONMENTAL REPORT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    BROOKHAVEN NATIONAL LABORATORY; RATEL,K.

    2007-10-01

    Each year, Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy. The report is written to inform the public, regulators, employees, and other stakeholders of BNL's environmental performance during the calendar year in review. The SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and compliance, restoration, and surveillance monitoring program performance. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inception in 1947.more » The report is available in print and as a downloadable file on the BNL web page at http://www.bnl.gov/ewms/ser/. A summary of the SER is also prepared each year to provide a general overview of the report, and is distributed with a CD of the full report.« less

  14. SITE CHARACTERIZATION LIBRARY VERSION 3.0

    EPA Science Inventory

    The Site Characterization Library is a CD that provides a centralized, field-portable source for site characterization information. Version 3 of the Site Characterization Library contains additional (from earlier versions) electronic documents and computer programs related to th...

  15. Online Sea Ice Knowledge and Data Platform: www.seaiceportal.de

    NASA Astrophysics Data System (ADS)

    Treffeisen, R. E.; Nicolaus, M.; Bartsch, A.; Fritzsch, B.; Grosfeld, K.; Haas, C.; Hendricks, S.; Heygster, G.; Hiller, W.; Krumpen, T.; Melsheimer, C.; Nicolaus, A.; Ricker, R.; Weigelt, M.

    2016-12-01

    There is an increasing public interest in sea ice information from both Polar Regions, which requires up-to-date background information and data sets at different levels for various target groups. In order to serve this interest and need, seaiceportal.de (originally: meereisportal.de) was developed as a comprehensive German knowledge platform on sea ice and its snow cover in the Arctic and Antarctic. It was launched in April 2013. Since then, the content and selection of data sets increased and the data portal received increasing attention, also from the international science community. Meanwhile, we are providing near-real time and archived data of many key parameters of sea ice and its snow cover. The data sets result from measurements acquired by various platforms as well as numerical simulations. Satellite observations (e.g., AMSR2, CryoSat-2 and SMOS) of sea ice concentration, freeboard, thickness and drift are available as gridded data sets. Sea ice and snow temperatures and thickness as well as atmospheric parameters are available from autonomous ice-tethered platforms (buoys). Additional ship observations, ice station measurements, and mooring time series are compiled as data collections over the last decade. In parallel, we are continuously extending our meta-data and uncertainty information for all data sets. In addition to the data portal, seaiceportal.de provides general comprehensive background information on sea ice and snow as well as expert statements on recent observations and developments. This content is mostly in German in order to complement the various existing international sites for the German speaking public. We will present the portal, its content and function, but we are also asking for direct user feedback and are open for potential new partners.

  16. Field-based ET calibration and validation sites in interior Alaska: Preparatory Science for NASA's planned HyspIRI Mission

    NASA Astrophysics Data System (ADS)

    Prakash, A.; Cristobal, J.; Fochesatto, G. J.; Starkenburg, D. P.; Kane, D. L.; Gens, R.; Alfieri, J. G.; Irving, K.; Anderson, M. C.; Kustas, W.

    2012-12-01

    Evapotranspiration (ET) is a critical component of the hydrologic cycle in interior Alaska, being about 74% of summer precipitation or 50% of annual precipitation, and is a process that will become more important as we witness increasing trends of climate warming, permafrost degradation, forest fire occurrences, and significant land cover changes. In preparation for NASA's planned Hyperspectral Infrared Imager (HyspIRI) satellite mission; we have established two experimental sites in interior Alaska to measure representative ET values for typical boreal forest in this region as a basis to estimate and upscale ET from remote sensing solar and thermal data. The first site (University of Alaska Fairbanks, UAF, north campus) is located in a needleleaf forest mainly composed of black spruce (Picea mariana) and the second site (Caribou-Poker Creek Research Watershed) is in a deciduous forest mainly composed of paper birch (Betula papyrifera). Both field sites are equipped with sonic anemometers and gas analyzers at 24 m height operating at a 20Hz sampling rate, and, additionally, the UAF north campus site includes a 3 and 12m sonic anemometers. At 24m, the tower is also equipped with a four component net radiometer sensor and air temperature and pressure sensors are installed at different heights. To monitor ground heat, temperature and soil moisture sensors as well as heat flux plates have also been installed in the organic and the subsurface soil layers. Additionally, a Large Aperture Scintillometer (LAS) transmitter and receiver units with a separation of 1.2 km have been installed across the tower ensuring a beam height of 24m. Data is recorded on data loggers and downloaded for quality check and processing on a weekly basis. Further details of tower set-up are available at www.et.alaska.edu. Data from the field instruments are presented and their use for Alaska specific ET model calibration are discussed. The field set-up provides all input data for ET modeling and

  17. 40 CFR 1065.1 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... regulated under vehicle-based, equipment-based, or vessel-based standards, use good engineering judgment to...) For additional information regarding these test procedures, visit our Web site at http://www.epa.gov...

  18. 40 CFR 1065.1 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... regulated under vehicle-based, equipment-based, or vessel-based standards, use good engineering judgment to...) For additional information regarding these test procedures, visit our Web site at http://www.epa.gov...

  19. 75 FR 55617 - National Science Board; Sunshine Act Meetings Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-13

    ... to the National Science Board Web site http://www.nsf.gov/nsb for additional information and schedule... of Deep Underground Science and Engineering Laboratory (DUSEL) on South Dakota Graduate Education in...

  20. Cost Effectiveness of On-site versus Off-site Depression Collaborative Care in Rural Federally Qualified Health Centers

    PubMed Central

    Pyne, Jeffrey M.; Fortney, John C.; Mouden, Sip; Lu, Liya; Hudson, Teresa J; Mittal, Dinesh

    2018-01-01

    Objective Collaborative care for depression is effective and cost-effective in primary care settings. However, there is minimal evidence to inform the choice of on-site versus off-site models. This study examined the cost-effectiveness of on-site practice-based collaborative care (PBCC) versus off-site telemedicine-based collaborative care (TBCC) for depression in Federally Qualified Health Centers (FQHCs). Methods Multi-site randomized pragmatic comparative cost-effectiveness trial. 19,285 patients were screened for depression, 14.8% (n=2,863) screened positive (PHQ9 ≥10) and 364 were enrolled. Telephone interview data were collected at baseline, 6-, 12-, and 18-months. Base case analysis used Arkansas FQHC healthcare costs and secondary analysis used national cost estimates. Effectiveness measures were depression-free days and quality-adjusted life years (QALYs) derived from depression-free days, Medical Outcomes Study SF-12, and Quality of Well Being scale (QWB). Nonparametric bootstrap with replacement methods were used to generate an empirical joint distribution of incremental costs and QALYs and acceptability curves. Results Mean base case FQHC incremental cost-effectiveness ratio (ICER) using depression-free days was $10.78/depression-free day. Mean base case ICERs using QALYs ranged from $14,754/QALY (depression-free day QALY) to $37,261/QALY (QWB QALY). Mean secondary national ICER using depression-free days was $8.43/depression-free day and using QALYs ranged from $11,532/QALY (depression-free day QALY) to $29,234/QALY (QWB QALY). Conclusions These results support the cost-effectiveness of the TBCC intervention in medically underserved primary care settings. Results can inform the decision about whether to insource (make) or outsource (buy) depression care management in the FQHC setting within the current context of Patient-Centered Medical Home, value-based purchasing, and potential bundled payments for depression care. The www.clinicaltrials.gov # for

  1. Guide to Sea Ice Information and Sea Ice Data Online - the Sea Ice Knowledge and Data Platform www.meereisportal.de and www.seaiceportal.de

    NASA Astrophysics Data System (ADS)

    Treffeisen, R. E.; Nicolaus, M.; Bartsch, A.; Fritzsch, B.; Grosfeld, K.; Haas, C.; Hendricks, S.; Heygster, G.; Hiller, W.; Krumpen, T.; Melsheimer, C.; Ricker, R.; Weigelt, M.

    2016-12-01

    The combination of multi-disciplinary sea ice science and the rising demand of society for up-to-date information and user customized products places emphasis on creating new ways of communication between science and society. The new knowledge platform is a contribution to the cross-linking of scientifically qualified information on climate change, and focuses on the theme: `sea ice' in both Polar Regions. With this platform, the science opens to these changing societal demands. It is the first comprehensive German speaking knowledge platform on sea ice; the platform went online in 2013. The web site delivers popularized information for the general public as well as scientific data meant primarily for the more expert readers and scientists. It also provides various tools allowing for visitor interaction. The demand for the web site indicates a high level of interest from both the general public and experts. It communicates science-based information to improve awareness and understanding of sea ice related research. The principle concept of the new knowledge platform is based on three pillars: (1) sea ice knowledge and background information, (2) data portal with visualizations, and (3) expert knowledge, latest research results and press releases. Since then, the content and selection of data sets increased and the data portal received increasing attention, also from the international science community. Meanwhile, we are providing near-real time and archived data of many key parameters of sea ice and its snow cover. The data sets result from measurements acquired by various platforms as well as numerical simulations. Satellite observations (e.g., AMSR2, CryoSat-2 and SMOS) of sea ice concentration, freeboard, thickness and drift are available as gridded data sets. Sea ice and snow temperatures and thickness as well as atmospheric parameters are available from autonomous ice-tethered platforms (buoys). Additional ship observations, ice station measurements, and

  2. 78 FR 12365 - Tennessee Valley Authority; Notice of Receipt and Availability of Application for Renewal of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-22

    ... 20852, or through the internet from the NRC's Agencywide Documents Access and Management System (ADAMS... Room is accessible from the NRC Web site at http://www.nrc.gov/reading-rm/adams.html . In addition, the... also be available to local residents near the site at the Chattanooga-Hamilton County Library...

  3. Delinquent Medical Service Accounts at David Grant Air Force Medical Center Need Additional Management Oversight

    DTIC Science & Technology

    2015-09-24

    No. DODIG-2015-179 S E P T E M B E R 2 4 , 2 0 1 5 Delinquent Medical Service Accounts at David Grant Air Force Medical Center Need Additional...us at www.dodig.mil Results in Brief Delinquent Medical Service Accounts at David Grant Air Force...Force Medical Center (DGMC) properly managed delinquent accounts over 180 days by effectively transferring the debt to the appropriate debt collection

  4. 77 FR 1526 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Relating...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ... other public sources, or on-line information services such as Bloomberg or Reuters. Each Benchmark and..., on the Web site of ICE Futures ( www.theice.com ). In addition, various data vendors and news... major market data vendors worldwide, including Bloomberg and Reuters. In addition, the Exchange further...

  5. 76 FR 17473 - Twelfth Meeting: RTCA Special Committee 214: Working Group 78: Standards for Air Traffic Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-29

    [email protected] , and copy to [email protected] . FOR FURTHER INFORMATION CONTACT: RTCA Secretariat, 1828... site http://www.rtca.org . SUPPLEMENTARY INFORMATION: Pursuant to section 10(a)(2) of the Federal... will include: Additional Information Additional information and all the documents to be considered can...

  6. 34 CFR 600.32 - Eligibility of additional locations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... reason other than a normal vacation period or a natural disaster that directly affects the institution or...)(1) An institution that conducts a teach-out at a site of a closed institution may apply to have that site approved as an additional location if— (i) The closed institution ceased operations and the...

  7. Integrating NASA Dryden Research Endeavors into the Teaching-Learning of Mathematics in the K-12 Classroom via the WWW

    NASA Technical Reports Server (NTRS)

    Ward, Robin A.

    2002-01-01

    The primary goal of this project was to continue populating the currently existing web site developed in 1998 in conjunction with the NASA Dryden Flight Research Center and California Polytechnic State University, with more mathematics lesson plans and activities that K-12 teachers, students, home-schoolers, and parents could access. All of the activities, while demonstrating some mathematical topic, also showcase the research endeavors of the NASA Dryden Flight Research Center. The website is located at: http://daniel.calpoly.edu/dfrc/Robin. The secondary goal of this project was to share the web-based activities with educators at various conferences and workshops. To address the primary goal of this project, over the past year, several new activities were posted on the web site and some of the existing activities were enhanced to contain more video clips, photos, and materials for teachers. To address the project's secondary goal, the web-based activities were showcased at several conferences and workshops. Additionally, in order to measure and assess the outreach impact of the web site, a link to the web site hitbox.com was established in April 2001, which allowed for the collection of traffic statistics against the web site (such as the domains of visitors, the frequency of visitors to this web site, etc.) Provided is a description of some of the newly created activities posted on the web site during the project period of 2001-2002, followed by a description of the conferences and workshops at which some of the web-based activities were showcased. Next is a brief summary of the web site's traffic statistics demonstrating its worldwide educational impact, followed by a listing of some of the awards and accolades the web site has received.

  8. Cleanups In My Community (CIMC) - Superfund National Priority List (NPL) Sites, National Layer

    EPA Pesticide Factsheets

    This data layer provides access to Superfund National Priority List Sites as part of the CIMC web service. Superfund is a program administered by the EPA to locate, investigate, and clean up worst hazardous waste sites throughout the United States. EPA administers the Superfund program in cooperation with individual states and tribal governments. These sites include abandoned warehouses, manufacturing facilities, processing plants, and landfills - the key word here being abandoned.Only NPL sites have been included in Cleanups in My Community thus far. EPA maintains the NPL, which identifies for the States and the public those sites or other releases that appear to warrant remedial (long term) actions. These NPL sites fall into the following categories:Proposed: Sites may be proposed for the NPL and then may be placed on the NPL as final or be removed from the Proposed NPL.Final: Those sites placed on the NPL are called final, and for these sites, a cleanup remedy is selected and implemented. However, it may be several years after construction of the remedy is completed before the hazardous substances are completely cleaned up or controlled in place.Deleted: After the clean up process is complete, and appropriate reviews confirm the area is cleaned up or the hazards are controlled, sites can be deleted from the NPL.For more information on the data provided through this web service, please see the processing steps below, and see more information here: https://www.

  9. Trends in free WWW-based E-learning Modules seen from the Learning Resource Server Medicine (LRSMed).

    PubMed

    Stausberg, Jürgen; Geueke, Martin; Bludßat, Kevin

    2005-01-01

    Despite the lost enthusiasm concerning E-learning a lot of material is available on the World Wide Web (WWW) free of charge. This material is collected and systematically described by services like the Learning Resource Server Medicine (LRSMed) at http://mmedia.medizin.uni-essen.de/portal/. With the LRSMed E-learning modules are made available for medical students by means of a metadata description that can be used for a catalogue search. The number of resources included has risen enormously from 100 in 1999 up to 805 today. Especially in 2004 there was an exponential increase in the LRSMed's content. Anatomy is still the field with the highest amount of available material, but general medicine has improved its position over the years and is now the second one. Technically and didactically simple material as scripts, textbooks, and link lists (called info services) is still dominating. Similar to 1999, there is not one module which could be truly referred to as tutorial dialogue. Simple material can not replace face-to-face-teaching. But it could be combined with conventional courses to establish some kind of blending learning. The scene of free E-learning modules on the WWW is ready to meet current challenges for efficient training of students and continuing education in medicine.

  10. 77 FR 2972 - City and Borough of Sitka, Alaska, Alaska; Notice of Availability of Environmental Assessment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-20

    ... 20426. The EA also may be viewed on the Commission's Internet Web site at ( www.ferc.gov ) using the ``eLibrary'' link. Enter the docket number excluding the last three digits in the docket number field to access the document. Additional information about the project is available from the Commission's Web site...

  11. From the Arctic to fetal life: physiological importance and structural basis of an 'additional' chloride-binding site in haemoglobin.

    PubMed

    De Rosa, M Cristina; Castagnola, Massimo; Bertonati, Claudia; Galtieri, Antonio; Giardina, Bruno

    2004-06-15

    Haemoglobins from mammals of sub-Arctic and Arctic species, as well as fetal human Hb, are all characterized by a significantly lower Delta H of oxygenation compared with the majority of mammalian haemoglobins from temperate species (exceptions are represented by some cold-resistant species, such as cow, horse and pig). This has been interpreted as an adaptive mechanism of great importance from a physiological point of view. To date, the molecular basis of this thermodynamic characteristic is still not known. In the present study, we show that binding of extra chloride (with respect to adult human Hb) ions to Hb would significantly contribute to lowering the overall heat of oxygenation, thus providing a molecular basis for the low effect of temperature on the oxygenation-deoxygenation cycle. To this aim, the oxygen binding properties of bovine Hb, bear (Ursus arctos) Hb and horse Hb, which are representative of this series of haemoglobins, have been studied with special regard to the effect of heterotropic ligands, such as organic phosphates (namely 2,3-diphosphoglycerate) and chloride. Functional results are consistent with a mechanism for ligand binding that involves an additional binding site for chloride ion. Analysis of computational chemistry results, obtained by the GRID program, further confirm the hypothesis that the reason for the lower Delta H of oxygenation is mainly due to an increase in the number of the oxygen-linked chloride-binding sites.

  12. Recent Additions for 1998

    EPA Science Inventory

    December 22, 1998
    Benchmark Dose Software

    December 16, 1998
    www.epa.gov/fedrgstr/E...

  13. Medical pioneers in cyberspace: German practice owners advertising on the WWW.

    PubMed

    Schuh, C

    1999-01-01

    In the last few years, the number of Internet users has increased explosively. In the same way the number of Internet users has exploded, the costs in the public health sector have also increased. This resulted cost saving efforts by those responsible people in politics and medical administration. These economy measures have impacted in particular the established physicians. The current German practice owners are faced with an unknown economic situation and are forced to think and act like businessmen. Doubts arise concerning the age-old tradition of the advertising prohibition. Now advertisement is recognized as an important necessity. This study was conducted to answer the following questions: Who are the pioneers among the German practice owners presenting themselves to the public with their own website? How do they differ from their colleagues not advertising on the WWW? What motives and expectations do they associate with their website? Built on a detailed analysis of the relevant German and international literature, hypotheses were developed which were empirically checked in the further course of the work. For this purpose, an online survey was conducted on the WWW among established German physicians with their own websites. 194 physicians participated and 159 valid questionnaires were included in the analysis. The study revealed the following results: The age and sex distribution as well as the distribution of medical specialties in the examined group correspond to the expectations. A high percentage of the respondents participated in a medical professional organization. The median time in practice for practice age of the respondents was a little more than ten years. Many of the websites have been online less than one year. The following hypotheses could only partly be confirmed by the results of the survey: Physicians from different specialties deal with their own website differently. The Internet Familiarity of the physicians is responsible for the

  14. Mars exobiology landing sites for future exploration

    NASA Technical Reports Server (NTRS)

    Landheim, Ragnhild; Greeley, Ronald; Desmarais, David; Farmer, Jack D.; Klein, Harold

    1993-01-01

    The selection of landing sites for Exobiology is an important issue for planning for future Mars missions. Results of a recent site selection study which focused on potential landing sites described in the Mars Landing Site Catalog are presented. In addition, basic Exobiology science objectives in Mars exploration are reviewed, and the procedures used in site evaluation and prioritization are outlined.

  15. The WWW as a research medium: an illustrative survey on paranormal belief.

    PubMed

    Göritz, A S; Schumacher, J

    2000-06-01

    Data collected with a short World Wide Web (WWW) survey on paranormal belief, age, sex, locus of control, extraversion, emotional and physical well-being, and mood were compared with findings from recent literature while controlling for effects of self-selection. Each variable was measured with one item. The sample comprised 342 women, 648 men, and 8 participants of unknown sex, of whom 76.7% were self-selected and 23.3% did not select themselves. There was a weak but, given the large sample, significant effect of self-selection regarding paranormal belief (rpb 932 = .08) but no relationships for paranormal belief and the examined variables. In the entire sample, statistically significant correlations ranging from .13 to .07 between paranormal belief and female sex, scores on external locus of control, good mood, extraversion, and emotional well-being corresponded with previous offline results.

  16. 77 FR 39959 - Draft Guidance To Implement Requirements for the Treatment of Air Quality Monitoring Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-06

    ... of the revised draft High Winds Guidance document, the EPA identifies example technical analyses that... identified analyses and any additional technical analyses that air agencies could use to demonstrate that the... Web site at http://www.epa.gov/ttn/analysis/exevents.htm for additional details on the draft non...

  17. 77 FR 17472 - Texas Eastern Transmission, LP, Algonquin Gas Transmission, LLC; Notice of Availability of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-26

    .... Paper copy versions of the EIS were mailed to those specifically requesting them; all others received a CD version. In addition, the EIS is available for public viewing on the FERC's Web site ( www.ferc.... Questions Additional information about the Project is available from the Commission's Office of External...

  18. SPEER-SERVER: a web server for prediction of protein specificity determining sites

    PubMed Central

    Chakraborty, Abhijit; Mandloi, Sapan; Lanczycki, Christopher J.; Panchenko, Anna R.; Chakrabarti, Saikat

    2012-01-01

    Sites that show specific conservation patterns within subsets of proteins in a protein family are likely to be involved in the development of functional specificity. These sites, generally termed specificity determining sites (SDS), might play a crucial role in binding to a specific substrate or proteins. Identification of SDS through experimental techniques is a slow, difficult and tedious job. Hence, it is very important to develop efficient computational methods that can more expediently identify SDS. Herein, we present Specificity prediction using amino acids’ Properties, Entropy and Evolution Rate (SPEER)-SERVER, a web server that predicts SDS by analyzing quantitative measures of the conservation patterns of protein sites based on their physico-chemical properties and the heterogeneity of evolutionary changes between and within the protein subfamilies. This web server provides an improved representation of results, adds useful input and output options and integrates a wide range of analysis and data visualization tools when compared with the original standalone version of the SPEER algorithm. Extensive benchmarking finds that SPEER-SERVER exhibits sensitivity and precision performance that, on average, meets or exceeds that of other currently available methods. SPEER-SERVER is available at http://www.hpppi.iicb.res.in/ss/. PMID:22689646

  19. SPEER-SERVER: a web server for prediction of protein specificity determining sites.

    PubMed

    Chakraborty, Abhijit; Mandloi, Sapan; Lanczycki, Christopher J; Panchenko, Anna R; Chakrabarti, Saikat

    2012-07-01

    Sites that show specific conservation patterns within subsets of proteins in a protein family are likely to be involved in the development of functional specificity. These sites, generally termed specificity determining sites (SDS), might play a crucial role in binding to a specific substrate or proteins. Identification of SDS through experimental techniques is a slow, difficult and tedious job. Hence, it is very important to develop efficient computational methods that can more expediently identify SDS. Herein, we present Specificity prediction using amino acids' Properties, Entropy and Evolution Rate (SPEER)-SERVER, a web server that predicts SDS by analyzing quantitative measures of the conservation patterns of protein sites based on their physico-chemical properties and the heterogeneity of evolutionary changes between and within the protein subfamilies. This web server provides an improved representation of results, adds useful input and output options and integrates a wide range of analysis and data visualization tools when compared with the original standalone version of the SPEER algorithm. Extensive benchmarking finds that SPEER-SERVER exhibits sensitivity and precision performance that, on average, meets or exceeds that of other currently available methods. SPEER-SERVER is available at http://www.hpppi.iicb.res.in/ss/.

  20. Software-supported USER cloning strategies for site-directed mutagenesis and DNA assembly.

    PubMed

    Genee, Hans Jasper; Bonde, Mads Tvillinggaard; Bagger, Frederik Otzen; Jespersen, Jakob Berg; Sommer, Morten O A; Wernersson, Rasmus; Olsen, Lars Rønn

    2015-03-20

    USER cloning is a fast and versatile method for engineering of plasmid DNA. We have developed a user friendly Web server tool that automates the design of optimal PCR primers for several distinct USER cloning-based applications. Our Web server, named AMUSER (Automated DNA Modifications with USER cloning), facilitates DNA assembly and introduction of virtually any type of site-directed mutagenesis by designing optimal PCR primers for the desired genetic changes. To demonstrate the utility, we designed primers for a simultaneous two-position site-directed mutagenesis of green fluorescent protein (GFP) to yellow fluorescent protein (YFP), which in a single step reaction resulted in a 94% cloning efficiency. AMUSER also supports degenerate nucleotide primers, single insert combinatorial assembly, and flexible parameters for PCR amplification. AMUSER is freely available online at http://www.cbs.dtu.dk/services/AMUSER/.

  1. Natural Capital - putting a value on geological sites

    NASA Astrophysics Data System (ADS)

    Dunlop, Lesley

    2017-04-01

    Natural Capital is a mechanism through which a value can be placed on nature allowing it to be considered alongside other assets. When the Government of the United Kingdom produced a Natural Environment White Paper (The Natural Choice: securing the value of nature) in 2012 there was no direct mention of geosites, geoheritage or geodiversity. One ambition of the Natural Environment White Paper was to stop environmental degradation and to rebuild natural capital and to value it. Whilst landscapes are mentioned in the paper geodiversity is not directly and this has been problematic for funding and recognition within the UK. Natural Capital is being used as the basis for many of the environmental reviews therefore it is essential that geodiversity can be included within this. The Natural Capital Committee defines natural capital as 'those elements of the natural environment which provide valuable goods and services to people'. In the main, these goods and services are related to ecology/biodiversity rather than to the full range of natural capital. Specifically, the values associated with abiotic nature (geodiversity) are frequently undervalued or ignored. The English Geodiversity Forum have been producing case studies as to how this might be done for different locations and this paper will present the work of this and how a value can be attributed to geodiversity. For example links to tourism and recreation within areas such as the Jurassic Coast World Heritage Site and the Black Country proposed Geopark are easy to place a value on but it is more difficult with educational, scientific sites. Using an ecosystems services and biodiversity analogies this paper presents a framework that can be adopted for evaluation of geological sites. Defra (2015) The state of natural capital: protecting and improving natural capital for prosperity and wellbeing. Department for Environment, Food & Rural Affairs, 73 pages https://www

  2. JASSA: a comprehensive tool for prediction of SUMOylation sites and SIMs.

    PubMed

    Beauclair, Guillaume; Bridier-Nahmias, Antoine; Zagury, Jean-François; Saïb, Ali; Zamborlini, Alessia

    2015-11-01

    Post-translational modification by the Small Ubiquitin-like Modifier (SUMO) proteins, a process termed SUMOylation, is involved in many fundamental cellular processes. SUMO proteins are conjugated to a protein substrate, creating an interface for the recruitment of cofactors harboring SUMO-interacting motifs (SIMs). Mapping both SUMO-conjugation sites and SIMs is required to study the functional consequence of SUMOylation. To define the best candidate sites for experimental validation we designed JASSA, a Joint Analyzer of SUMOylation site and SIMs. JASSA is a predictor that uses a scoring system based on a Position Frequency Matrix derived from the alignment of experimental SUMOylation sites or SIMs. Compared with existing web-tools, JASSA displays on par or better performances. Novel features were implemented towards a better evaluation of the prediction, including identification of database hits matching the query sequence and representation of candidate sites within the secondary structural elements and/or the 3D fold of the protein of interest, retrievable from deposited PDB files. JASSA is freely accessible at http://www.jassa.fr/. Website is implemented in PHP and MySQL, with all major browsers supported. guillaume.beauclair@inserm.fr Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  3. 32 CFR 701.102 - Online resources.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... online Web site (http://www.privacy.navy.mil). This Web site supplements this subpart and subpart G. It...) Web site (http://www.doncio.navy.mil). This Web site provides detailed guidance on PIAs. (c) DOD's PA Web site (http://www.defenselink.mil/privacy). This Web site is an excellent resource that contains a...

  4. Reuse of Winery Wastewater by Application to Vineyard Soils

    NASA Astrophysics Data System (ADS)

    Mosse, K. P.; Patti, A. F.; Parikh, S.; Steenwerth, K. L.; Buelow, M. C.; Cavagnaro, T. R.

    2010-12-01

    The ability to reuse winery wastewater (WWW) has potential benefits both with respect to treatment of a waste stream, as well as providing a beneficial water resource in water limited regions such as south-eastern Australia, California and South Africa. Our study in south-eastern Australia and California has focused on characterizing the physicochemical properties and microbial communities on soils following WWW application. Studies in the Yarra Valley, Victoria, Australia considered the effect of a single WWW application on paired soil sites, one of which was acclimatized to WWW application via 30 years of this practice, and the other of which was not. Soils that had received WWW appear to have a primed microbial population, with soil respiration showing a significantly greater spike following the single WWW application. In addition, the nitrate and ammonium spikes were impacted upon in the acclimatised site. Taken together, this information suggests that long-term WWW application causes an alteration to the microbial community, which may be more readily able to assimilate the carbon and nitrogen sources present in WWW. Studies are currently underway to assess the impacts of the application of a synthetic WWW on vineyard soils in Davis, California. In this study, four different synthetic WWWs are being applied as irrigation water, and soil will be sampled at the time of grape harvest. Results from this ongoing work will be presented with a view to informing long term vineyard management for sustainability.

  5. Localized melt-scan strategy for site specific control of grain size and primary dendrite arm spacing in electron beam additive manufacturing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Raghavan, Narendran; Simunovic, Srdjan; Dehoff, Ryan

    In addition to design geometry, surface roughness, and solid-state phase transformation, solidification microstructure plays a crucial role in controlling the performance of additively manufactured components. Crystallographic texture, primary dendrite arm spacing (PDAS), and grain size are directly correlated to local solidification conditions. We have developed a new melt-scan strategy for inducing site specific, on-demand control of solidification microstructure. We were able to induce variations in grain size (30 μm–150 μm) and PDAS (4 μm - 10 μm) in Inconel 718 parts produced by the electron beam additive manufacturing system (Arcam®). A conventional raster melt-scan resulted in a grain size ofmore » about 600 μm. The observed variations in grain size with different melt-scan strategies are rationalized using a numerical thermal and solidification model which accounts for the transient curvature of the melt pool and associated thermal gradients and liquid-solid interface velocities. The refinement in grain size at high cooling rates (>104 K/s) is also attributed to the potential heterogeneous nucleation of grains ahead of the epitaxially growing solidification front. The variation in PDAS is rationalized using a coupled numerical-theoretical model as a function of local solidification conditions (thermal gradient and liquid-solid interface velocity) of the melt pool.« less

  6. CUES - A Study Site for Measuring Snowpack Energy Balance in the Sierra Nevada

    NASA Astrophysics Data System (ADS)

    Bair, Edward; Dozier, Jeff; Davis, Robert; Colee, Michael; Claffey, Keran

    2015-09-01

    Accurate measurement and modeling of the snowpack energy balance are critical to understanding the terrestrial water cycle. Most of the water resources in the western US come from snowmelt, yet statistical runoff models that rely on the historical record are becoming less reliable because of a changing climate. For physically based snow melt models that do not depend on past conditions, ground based measurements of the energy balance components are imperative for verification. For this purpose, the US Army Corps of Engineers Cold Regions Research and Engineering Laboratory (CRREL) and the University of California, Santa Barbara (UCSB) established the “CUES” snow study site (CRREL/UCSB Energy Site, http://www.snow.ucsb.edu/) at 2940 m elevation on Mammoth Mountain, California. We describe CUES, provide an overview of research, share our experience with scientific measurements, and encourage future collaborative research. Snow measurements began near the current CUES site for ski area operations in 1969. In the 1970s, researchers began taking scientific measurements. Today, CUES benefits from year round gondola access and a fiber optic internet connection. Data loggers and computers automatically record and store over 100 measurements from more than 50 instruments each minute. CUES is one of only five high altitude mountain sites in the Western US where a full suite of energy balance components are measured. In addition to measuring snow on the ground at multiple locations, extensive radiometric and meteorological measurements are recorded. Some of the more novel measurements include scans by an automated terrestrial LiDAR, passive and active microwave imaging of snow stratigraphy, microscopic imaging of snow grains, snowflake imaging with a multi-angle camera, fluxes from upward and downward looking radiometers, snow water equivalent from different types of snow pillows, snowmelt from lysimeters, and concentration of impurities in the snowpack. We give an

  7. American Recovery and Reinvestment Act Wind Turbine Projects at Long-Range Radar Sites in Alaska Were Not Adequately Planned

    DTIC Science & Technology

    2011-09-30

    Ratio TAFS Treasury Appropriation Fund Symbol INSPECTOR GENERAL DEPARTMENT OF DEFENSE 400 ARMY NAVY DRIVE ARLINGTON, VIRGINIA 22202-4704...Symbol ( TAFS ) to the www.recovery.gov Web site. As a result of our review, officials at AFCESA took action to correct the errors in the...projects in a timely manner, and the funding authorization documents properly identified a Recovery Act designation. Funding documents cited a TAFS of

  8. Usage of the www.2aida.org AIDA diabetes software Website: a pilot study.

    PubMed

    Lehmann, Eldon D

    2003-01-01

    AIDA is a diabetes-computing program freely available from www.2aida.org on the Web. The software is intended to serve as an educational support tool, and can be used by anyone who has an interest in diabetes, whether they be patients, relatives, health-care professionals, or students. In previous "Diabetes Information Technology & WebWatch" columns various indicators of usage of the AIDA program have been reviewed, and various comments from users of the software have been documented. One aspect of AIDA, though, that has been of considerable interest has been to investigate its Web-based distribution as a wider paradigm for more general medically related usage of the Internet. In this respect we have been keen to understand in general terms: (1) why people are turning to the Web for health-care/diabetes information; (2) more specifically, what sort of people are making use of the AIDA software; and (3) what benefits they feel might accrue from using the program. To answer these types of questions we have been conducting a series of audits/surveys via the AIDA Website, and via the software program itself, to learn as much as possible about who the AIDA end users really are. The rationale for this work is that, in this way, it should be possible to improve the program as well as tailor future versions of the software to the interests and needs of its users. However, a recurring observation is that data collection is easiest if it is as unobtrusive and innocuous as possible. One aspect of learning as much as possible about diabetes Website visitors and users may be to apply techniques that do not necessitate any visitor or user interaction. There are various programs that can monitor what pages visitors are viewing at a site. As these programs do not require visitors to do anything special, over time some interesting insights into Website usage may be obtained. For the current study we have reviewed anonymous logstats data, which are automatically collected at many

  9. Using the WWW to supply the molecular biology lab.

    PubMed

    Labant, M; Anderson, R

    2000-01-01

    The World Wide Web is changing the face of business today and will continue to reshape it in the coming years. Nonvalue-added processes are being eliminated as organizations reengineer their internal ways of doing business in a continual effort to reduce costs and remain competitive. Current electronic market followers claim that gateways, or portals, of information will be the wave of the future. This does not mean that individual suppliers' websites will become extinct. It means that content will continue to change and adapt so that sites will continue to be more useful. If gateways do turn out to be the user's choice for product information presentation in the future, expect more consolidated sites devoted to specific product categories, such as chemicals, molecular biology supplies, and the like.

  10. A Worldwide Web-portal for Aquatic Mesocosm Facilities: WWW.MESOCOSM.EU

    NASA Astrophysics Data System (ADS)

    Berger, S. A.; Nejstgaard, J. C.

    2016-02-01

    Experimental mesocosms are valuable tools to fill the gap between highly controlled/replicated lab experiments and uncontrolled/non-replicated natural environments such as rivers, lakes and oceans. WWW.MESOCOSM.EU is an open web-portal for leading aquatic mesocosm facilities around the world. It was created within the FP7 EU-project MESOAQUA (A network of leading MESOcosm facilities to advance the studies of future AQUAtic ecosystems from the Arctic to the Mediterranean). The goal of the portal is to increase international knowledge about existing mesocosm facilities, including information on locations, environment, equipment, contacts, research opportunities and mesocosm-based publications. MESOCOSM.EU specifically aims to be a tool to enhance the quality of research by facilitating international cooperative network building, announcement of new research initiatives, transfer of best practice, and dissemination of knowledge, public information and press releases. As an open platform for all aquatic ecosystem scale science (marine and freshwater), MESOCOSM.EU aims to fill the lack of a centralized, coordinating virtual infrastructure for international aquatic mesocosm research, from the mountains to the ocean and from polar to tropical regions.

  11. Nitrogen addition increases fecundity in the desert shrub Sarcobatus vermiculatus.

    PubMed

    Drenovsky, R E; Richards, J H

    2005-04-01

    Nutrients, in addition to water, limit desert primary productivity, but nutrient limitations to fecundity and seed quality in desert ecosystems have received little attention. Reduced seed production and quality may affect recruitment, population, and community processes. At the Mono Basin, CA, USA where the alkaline, sandy soil has very low availability of N, P, and most other nutrients, seed production, recruitment, and dominance of the desert shrub Sarcobatus vermiculatus decrease over a dune successional sequence. Concurrently, Sarcobatus leaf N, P, and Ca/Mg ratio decline from early to later successional dunes. At two later successional dune sites, we fertilized adult Sarcobatus shrubs for 2 years and determined which nutrient(s) limited growth, seed production, and seed quality. We also tested whether nutrient addition at these older sites made these fitness-related variables equivalent to a younger, high-fecundity site. Nitrogen addition, alone, increased Sarcobatus leaf N, growth, and seed production per shoot module. Any treatment including P, Ca, Mg, or micronutrients but not N had an insignificant effect on growth and fecundity. Nitrogen addition also increased filled seed weight, a predictor of potential seedling survival, at one of the sites. Nitrogen-limited seed production and seed mass may reduce Sarcobatus fitness and contribute to the observed successional changes in plant community composition in this alkaline desert ecosystem.

  12. REGENERATIVE SITE LEARNING LABORATORY: A SITE INTERVENTION FOR SUSTAINABILITY EDUCATION

    EPA Science Inventory

    The project will indicate strategies that can be used to mitigate the negative impact of an existing developed site on a watershed and natural habitats. Additionally, the project design will inspire interest in ecological sustainability in an educational context. The project ...

  13. 10 CFR 13.26 - Filing and service of papers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... found in the E-Filing Guidance and on the NRC Web site at http://www.nrc.gov/site-help/e-submittals.html... electronically to the E-Filing system. In addition, optical storage media (OSM) containing the entire filing must... document (e.g., motion to quash subpoena). (6) Filing is complete when the filer performs the last act that...

  14. 75 FR 61779 - National Science Board: Sunshine Act Meetings; Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-06

    ...:30 p.m. to 3 p.m. SUBJECT MATTER: Review of NSB Action Item (NSB/CPP-10-63) (Deep Underground Science... National Science Board Web site http://www.nsf.gov/nsb for additional information and schedule updates...

  15. 77 FR 58443 - Migratory Bird Hunting; Final Frameworks for Late-Season Migratory Bird Hunting Regulations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... address above, or from the Division of Migratory Bird Management's Web site at http://www.fws.gov... INFORMATION CONTACT or from our Web site at http://www.fws.gov/migratorybirds . Review of Public Comments and... http://www.regulations.gov , or from our Web site at http://www.fws.gov/migratorybirds/NewReports...

  16. The K+/site and H+/site stoichiometry of mitochondrial electron transport.

    PubMed

    Reynafarje, B; Lehninger, A L

    1978-09-25

    Electrode measurements of the average number of H+ ejected and K+ taken up (in the presence of valinomycin) per pair of electrons passing the energy-conserving sites of the respiratory chain of rat liver and rat heart mitochondria have given identical values of the H+/site and 5+/site ratios very close to 4 in the presence of N-ethylmaleimide, an inhibitor of interfering respiration-coupled uptake of H+ + H2PO4-. The K+/site uptake ratio of 4 not only shows that inward movement of K+ provides quantitative charge-compensation for the 4 H+ ejected, but also confirms that 4 charges are separated per pair of electrons per site. When N-ethylmaleimide is omitted, the H+/site ejection ratio is depressed, because of the interfering secondary uptake of H/+ with H2PO4- on the phosphate carrier, but the K+/site uptake ratio remains at 4.0. Addition of phosphate or acetate, which can carry H+ into respiring mitochondria, further depresses the H+/site ratio, but does not affect the K+/site ratio, which remains at 4.0. These and other considerations thus confirm our earlier stoichiometric measurements that the average H+/site ratio is 4.0 and also show that the K+/site uptake ratio can be used as a measure of the intrinsic H+/site ratio, regardless of the presence of phosphate in the medium and without the necessity of adding N-ethylmaleimide or other inhibitors of H+ + H2PO4- transport.

  17. Report on Lessons Learned from the NP 2010 Early Site Permit Program FINAL REPORT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    2008-03-26

    This report provides a summary of lessons learned from the demonstration of the licensing process for three Early Site Permit (ESP) applications supported as part of the Department of Energy’s (DOE) Nuclear Power 2010 (NP 2010) program. The ESP process was established by the Nuclear Regulatory Commission (NRC) to enable completion of the site evaluation component of nuclear power plant licensing under 10 CFR Part 52 before a utility makes a decision to build a plant. Early Site Permits are valid for 10 to 20 years and can be renewed for an additional 10 to 20 years. NRC review ofmore » an ESP application addresses site safety issues, environmental protection issues, and plans for coping with emergencies. Successful completion of the ESP process will establish that a site is suitable for possible future construction and operation of a nuclear power plant. Most importantly, an ESP resolves significant site-related safety and environmental issues early in the decision process and helps achieve acceptance by the public. DOE competitively selected Dominion Nuclear Energy North Anna, LLC (Dominion); System Energy Resources, Inc. (an Entergy subsidiary); and Exelon Generation Company, LLC (Exelon) in 2002 to demonstrate the ESP process and provided cost-shared support through the NP 2010 program. Dominion pursued an ESP for the North Anna site in Virginia; System Energy Resources, Inc. pursued an ESP for the Grand Gulf site in Mississippi; and Exelon pursued an ESP for the Clinton site in Illinois. After successfully demonstrating the process, the NRC issued an ESP for Clinton on March 17, 2007; Grand Gulf on April 5, 2007; and North Anna on November 27, 2007. As with all successful projects, there are lessons to be learned from the NP 2010 early site permitting demonstration that can help improve future implementation guidance documents and regulatory review standards. In general, these lessons pertain to the effectiveness of the regulatory process, experience

  18. Outcome of bone marrow instillation at fracture site in intracapsular fracture of femoral neck treated by head preserving surgery.

    PubMed

    Verma, Nikhil; Singh, M P; Ul-Haq, Rehan; Rajnish, Rajesh K; Anshuman, Rahul

    2017-08-01

    The aim of present study is to evaluate the outcome of bone marrow instillation at the fracture site in fracture of intracapsular neck femur treated by head preserving surgery. This study included 32 patients of age group 18-50 years with closed fracture of intracapsular neck femur. Patients were randomized into two groups as per the plan generated via www.randomization.com. The two groups were Group A (control), in which the fracture of intracapsular neck femur was treated by closed reduction and cannulated cancellous screw fixation, and Group B (intervention), in which additional percutaneous autologous bone marrow aspirate instillation at fracture site was done along with cannulated cancellous screw fixation. Postoperatively the union at fracture site and avascular necrosis of the femoral head were assessed on serial plain radiographs at final follow-up. Functional outcome was evaluated by Harris hip score. The average follow-up was 19.6 months. Twelve patients in each group had union and 4 patients had signs of nonunion. One patient from each group had avascular necrosis of the femoral head. The average Harris hip score at final follow-up in Group A was 80.50 and in Group B was 75.73, which was found to be not significant. There is no significant role of adding on bone marrow aspirate instillation at the fracture site in cases of fresh fracture of intracapsular neck femur treated by head preserving surgery in terms of accelerating the bone healing and reducing the incidence of femoral head necrosis. Copyright © 2017 Daping Hospital and the Research Institute of Surgery of the Third Military Medical University. Production and hosting by Elsevier B.V. All rights reserved.

  19. 26 CFR 301.6320-1 - Notice and opportunity for hearing upon filing of notice of Federal tax lien.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., by downloading a copy from the IRS Internet site, http://www.irs.gov/pub/irs-pdf/f12153.pdf, or by... result of an additional assessment of tax (not including interest or penalties) for that period or an... another CDP hearing under section 6320 if the additional assessment represents accruals of interest...

  20. 26 CFR 301.6320-1 - Notice and opportunity for hearing upon filing of notice of Federal tax lien.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., by downloading a copy from the IRS Internet site, http://www.irs.gov/pub/irs-pdf/f12153.pdf, or by... result of an additional assessment of tax (not including interest or penalties) for that period or an... another CDP hearing under section 6320 if the additional assessment represents accruals of interest...

  1. 26 CFR 301.6320-1 - Notice and opportunity for hearing upon filing of notice of Federal tax lien.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., by downloading a copy from the IRS Internet site, http://www.irs.gov/pub/irs-pdf/f12153.pdf, or by... result of an additional assessment of tax (not including interest or penalties) for that period or an... another CDP hearing under section 6320 if the additional assessment represents accruals of interest...

  2. Website Use and Effects of Online Information About Tobacco Additives Among the Dutch General Population: A Randomized Controlled Trial.

    PubMed

    Reinwand, Dominique A; Crutzen, Rik; Kienhuis, Anne S; Talhout, Reinskje; de Vries, Hein

    2017-03-14

    communication about the risks of tobacco additives. Nederlands Trial Register NTR4620; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=4620 (Archived by WebCite at http://www.webcitation.org/6oW7w4Gnj). ©Dominique A Reinwand, Rik Crutzen, Anne S Kienhuis, Reinskje Talhout, Hein de Vries. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 14.03.2017.

  3. Developing Study Stations on Your School Site.

    ERIC Educational Resources Information Center

    Ohio State Dept. of Natural Resources, Columbus. Office of Information and Education.

    The school site is a convenient location for study stations since it is available for short periods of time and can be used consistently. Special preparations, such as transportation, required for off-site fieldtrips can be eliminated. In addition, on-site activities provide students with concrete experiences necessary to understand difficult…

  4. Transcription Factor Information System (TFIS): A Tool for Detection of Transcription Factor Binding Sites.

    PubMed

    Narad, Priyanka; Kumar, Abhishek; Chakraborty, Amlan; Patni, Pranav; Sengupta, Abhishek; Wadhwa, Gulshan; Upadhyaya, K C

    2017-09-01

    Transcription factors are trans-acting proteins that interact with specific nucleotide sequences known as transcription factor binding site (TFBS), and these interactions are implicated in regulation of the gene expression. Regulation of transcriptional activation of a gene often involves multiple interactions of transcription factors with various sequence elements. Identification of these sequence elements is the first step in understanding the underlying molecular mechanism(s) that regulate the gene expression. For in silico identification of these sequence elements, we have developed an online computational tool named transcription factor information system (TFIS) for detecting TFBS for the first time using a collection of JAVA programs and is mainly based on TFBS detection using position weight matrix (PWM). The database used for obtaining position frequency matrices (PFM) is JASPAR and HOCOMOCO, which is an open-access database of transcription factor binding profiles. Pseudo-counts are used while converting PFM to PWM, and TFBS detection is carried out on the basis of percent score taken as threshold value. TFIS is equipped with advanced features such as direct sequence retrieving from NCBI database using gene identification number and accession number, detecting binding site for common TF in a batch of gene sequences, and TFBS detection after generating PWM from known raw binding sequences in addition to general detection methods. TFIS can detect the presence of potential TFBSs in both the directions at the same time. This feature increases its efficiency. And the results for this dual detection are presented in different colors specific to the orientation of the binding site. Results obtained by the TFIS are more detailed and specific to the detected TFs as integration of more informative links from various related web servers are added in the result pages like Gene Ontology, PAZAR database and Transcription Factor Encyclopedia in addition to NCBI and Uni

  5. The use of UAVs to monitor archeological sites: the case study of Choirokoitia within the PROTHEGO project

    NASA Astrophysics Data System (ADS)

    Themistocleous, K.

    2017-09-01

    PROTHEGO (PROTection of European Cultural HEritage from GeO-hazards) is a collaborative research project funded in the framework of the Joint Programming Initiative on Cultural Heritage and Global Change (JPICH) - Heritage Plus in 2015-2018 (www.prothego.eu). PROTHEGO aims to make an innovative contribution towards the analysis of geo-hazards in areas of cultural heritage, and uses novel space technology for the management of sites and world heritage monuments located throughout Europe, using specialized remote sensing techniques. Τhe methodology will include the 395 monuments of UNESCO in Europe, with case studies conducted in 4 UNESCO sites in England, Spain, Italy and Cyprus. For the Cyprus case study in Choirokoitia, Unmanned Aerial Vehicles (UAVs) are used to monitor and assess the risk from natural hazards on the archaeological site to evaluate cultural heritage sites deformation. The UAVs were flown over the study area to produce time-series data, including orthoimages, 3D models and digital elevation models of the Choirokoitia site in order to identify changes in the area caused by natural hazards.

  6. SITEX 2.0: Projections of protein functional sites on eukaryotic genes. Extension with orthologous genes.

    PubMed

    Medvedeva, Irina V; Demenkov, Pavel S; Ivanisenko, Vladimir A

    2017-04-01

    Functional sites define the diversity of protein functions and are the central object of research of the structural and functional organization of proteins. The mechanisms underlying protein functional sites emergence and their variability during evolution are distinguished by duplication, shuffling, insertion and deletion of the exons in genes. The study of the correlation between a site structure and exon structure serves as the basis for the in-depth understanding of sites organization. In this regard, the development of programming resources that allow the realization of the mutual projection of exon structure of genes and primary and tertiary structures of encoded proteins is still the actual problem. Previously, we developed the SitEx system that provides information about protein and gene sequences with mapped exon borders and protein functional sites amino acid positions. The database included information on proteins with known 3D structure. However, data with respect to orthologs was not available. Therefore, we added the projection of sites positions to the exon structures of orthologs in SitEx 2.0. We implemented a search through database using site conservation variability and site discontinuity through exon structure. Inclusion of the information on orthologs allowed to expand the possibilities of SitEx usage for solving problems regarding the analysis of the structural and functional organization of proteins. Database URL: http://www-bionet.sscc.ru/sitex/ .

  7. Integration of Live Video and WWW Delivery Systems To Teach University Level Science, Technology, and Society in High Schools.

    ERIC Educational Resources Information Center

    Urven, Lance E.; Yin, L. Roger; Bak, John D.

    In fall 1997, the University of Wisconsin-Whitewater (UWW) provided Science and Technology in Society, a university general studies science literacy course, to advanced placement high school students at three local high schools, using a combination of live video presentations and World Wide Web (WWW) courseware. A total of 26 high school students…

  8. 76 FR 47538 - Sacred Sites; Executive Order 13007

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-05

    ... is available for review and comment at http://www.fs.fed.us/spf/tribalrelations/sacredsites . DATES.... The draft report, and other associated information, is available at: http://www.fs.fed.us/spf...

  9. 77 FR 43574 - National Climate Assessment and Development Advisory Committee (NCADAC); Open Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration (NOAA) National Climate... NOAA National Climate Assessment and Development Advisory Committee (NCADAC). Time and Date: The... check the National Climate Assessment Web site for additional information at http://www.globalchange.gov...

  10. Sharing Site-Based Research Data: Standardizing and Packaging for Reuse

    NASA Astrophysics Data System (ADS)

    Gordon, S.; DiLauro, T.; Jett, J. G.; Thomer, A.

    2014-12-01

    One of the key aims of the Institute of Museum and Library Services-funded Site-Based Data Curation (SBDC) Project[1] is to increase the reuse of data gathered or generated through research at sites like Yellowstone National Park (YNP) by improving its usefulness, discoverability, and accessibility. Toward this goal, SBDC worked closely with a geobiologist conducting fieldwork at YNP to explore existing data practices and held a two-day stakeholders workshop at the park with some of the scientists who study it and the National Park Service (NPS) staff who support research activities there. The resulting workshop report[2] recommends, among other things, improvements to the level of detail and consistency of documentation of data and of its sampling and analysis methods. A set of core metadata elements and domain-specific extension elements is proposed (Appendix 9) to provide a more coherent view into the data. Armed with these findings, we are pursuing approaches that will reduce the effort, complexity, and risk tied to adoption of these recommendations. During our investigation, we discovered the EarthChem templates[3], into which we began mapping the geobiologist's data. We find the Vent Fluids template particularly appropriate and adaptable, as many of the high-interest features at YNP are shallow water vents. We are currently building an EarthChem-compatible template that will capture the environmental context of microbes, tracing their identities from water sample through to GenBank entry. Given the variety of potential targets (e.g., site, institutional, and domain repositories; visualization and presentation tools), we decided to record the data in a structured package, which we can transform for a given target. We are using the Data Conservancy's Packaging Tool[4], which provides an intuitive file system view, stores file checksums, and serializes a graph of relationships. This permits a researcher to conveniently group desired data products into a single

  11. 26 CFR 301.6330-1 - Notice and opportunity for hearing prior to levy.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... copy from the IRS Internet site, http://www.irs.gov/pub/irs-pdf/f12153.pdf, or by calling, toll-free, 1... including interest or penalties) for that period or an additional accuracy-related or filing-delinquency... additional assessment represents accruals of interest, accruals of penalties, or both. Q-D2. Will a CDP...

  12. 26 CFR 301.6330-1 - Notice and opportunity for hearing prior to levy.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... copy from the IRS Internet site, http://www.irs.gov/pub/irs-pdf/f12153.pdf, or by calling, toll-free, 1... including interest or penalties) for that period or an additional accuracy-related or filing-delinquency... additional assessment represents accruals of interest, accruals of penalties, or both. Q-D2. Will a CDP...

  13. 26 CFR 301.6330-1 - Notice and opportunity for hearing prior to levy.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... copy from the IRS Internet site, http://www.irs.gov/pub/irs-pdf/f12153.pdf, or by calling, toll-free, 1... including interest or penalties) for that period or an additional accuracy-related or filing-delinquency... additional assessment represents accruals of interest, accruals of penalties, or both. Q-D2. Will a CDP...

  14. e23D: database and visualization of A-to-I RNA editing sites mapped to 3D protein structures.

    PubMed

    Solomon, Oz; Eyal, Eran; Amariglio, Ninette; Unger, Ron; Rechavi, Gidi

    2016-07-15

    e23D, a database of A-to-I RNA editing sites from human, mouse and fly mapped to evolutionary related protein 3D structures, is presented. Genomic coordinates of A-to-I RNA editing sites are converted to protein coordinates and mapped onto 3D structures from PDB or theoretical models from ModBase. e23D allows visualization of the protein structure, modeling of recoding events and orientation of the editing with respect to nearby genomic functional sites from databases of disease causing mutations and genomic polymorphism. http://www.sheba-cancer.org.il/e23D CONTACT: oz.solomon@live.biu.ac.il or Eran.Eyal@sheba.health.gov.il. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  15. 9 CFR 94.9 - Pork and pork products from regions where classical swine fever exists.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... declared free of classical swine fever is maintained on the APHIS Web site at http://www.aphis.usda.gov... which they must be cooked in hot oil (deep-fried) at a minimum of 104 °C for an additional 150 minutes...

  16. 9 CFR 94.9 - Pork and pork products from regions where classical swine fever exists.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... swine fever is maintained on the APHIS Web site at http://www.aphis.usda.gov/import_export/animals... which they must be cooked in hot oil (deep-fried) at a minimum of 104 °C for an additional 150 minutes...

  17. 9 CFR 94.12 - Pork and pork products from regions where swine vesicular disease exists.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... has declared free of swine vesicular disease is maintained on the APHIS Web site at http://www.aphis... which they must be cooked in hot oil (deep-fried) at a minimum of 104 °C for an additional 150 minutes...

  18. Site Rehabilitation Completion Report with No Further Action Proposal for the Northeast Site

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Daniel, Joe; Tabor, Charles; Survochak, Scott

    2013-05-01

    The purpose of this Site Rehabilitation Completion Report is to present the post-active-remediation monitoring results for the Northeast Site and to propose No Further Action with Controls. This document includes information required by Chapter 62-780.750(4)(d), 62-780.750(6), and 62-780.600(8)(a)27 Florida Administrative Code (F.A.C.). The Closure Monitoring Plan for the Northeast Site and 4.5 Acre Site (DOE 2009a) describes the approach for post-active-remediation monitoring. The Young - Rainey Science, Technology, and Research Center (STAR Center) is a former U.S. Department of Energy (DOE) facility constructed in the mid-1950s. The 99-acre STAR Center is located in Largo, Florida. The Northeast Site is locatedmore » in the northeast corner of the STAR Center. The Northeast Site meets all the requirements for an RMO II closure—No Further Action with Controls. DOE is nearing completion of a restrictive covenant for the Northeast Site. DOE has completed post-active-remediation monitoring at the Northeast Site as of September 2012. No additional monitoring will be conducted.« less

  19. Amino-Acid Network Clique Analysis of Protein Mutation Non-Additive Effects: A Case Study of Lysozme.

    PubMed

    Ming, Dengming; Chen, Rui; Huang, He

    2018-05-10

    Optimizing amino-acid mutations in enzyme design has been a very challenging task in modern bio-industrial applications. It is well known that many successful designs often hinge on extensive correlations among mutations at different sites within the enzyme, however, the underpinning mechanism for these correlations is far from clear. Here, we present a topology-based model to quantitively characterize non-additive effects between mutations. The method is based on the molecular dynamic simulations and the amino-acid network clique analysis. It examines if the two mutation sites of a double-site mutation fall into to a 3-clique structure, and associates such topological property of mutational site spatial distribution with mutation additivity features. We analyzed 13 dual mutations of T4 phage lysozyme and found that the clique-based model successfully distinguishes highly correlated or non-additive double-site mutations from those additive ones whose component mutations have less correlation. We also applied the model to protein Eglin c whose structural topology is significantly different from that of T4 phage lysozyme, and found that the model can, to some extension, still identify non-additive mutations from additive ones. Our calculations showed that mutation non-additive effects may heavily depend on a structural topology relationship between mutation sites, which can be quantitatively determined using amino-acid network k -cliques. We also showed that double-site mutation correlations can be significantly altered by exerting a third mutation, indicating that more detailed physicochemical interactions should be considered along with the network clique-based model for better understanding of this elusive mutation-correlation principle.

  20. Does taping in addition to physiotherapy improve the outcomes in subacromial impingement syndrome? A systematic review.

    PubMed

    Saracoglu, Ismail; Emuk, Yusuf; Taspinar, Ferruh

    2018-04-01

    Taping is used with or without other interventions for many purposes, especially to manage pain and improve functional activity in patients with shoulder pain. The aim of this review was to determine whether any taping technique in addition to physiotherapy care is more effective than physiotherapy care alone in patients with shoulder impingement syndrome. A systematic search of Cochrane Database of Systematic Review, MEDLINE (EBSCO), Physiotherapy Evidence Database (PEDro), CINAHL (EBSCO), PUBMED, AMED, EMBASE (OVID), The Kinesio Kinesio® Taping Method, Kinesio® Tex Tape UK and International websites ( www.kinesiotaping.co.uk ; www.kinesiotaping.com ) was conducted to June 2015. The outcome measures were pain, disability, range of motion and muscle strength. As data were not suitable for meta-analysis, narrative synthesis were applied. Three randomized controlled trials and one controlled trial (135 patients) were included. The results were conflicting and weak on the effectiveness of taping as an adjunct therapy for improvement of pain, disability, range of motion and muscle strength. Clinical taping in addition to physiotherapy interventions (e.g. exercise, electrotherapy, and manual therapy) might be an optional modality for managing patients with shoulder impingement syndrome, especially for the initial stage of the treatment; however, we need further robust, placebo controlled and consistent studies to prove whether it is more effective than physiotherapy interventions without taping.

  1. Soil nutrient additions increase invertebrate herbivore abundances, but not herbivory, across three grassland systems.

    PubMed

    La Pierre, Kimberly J; Smith, Melinda D

    2016-02-01

    Resource availability may influence invertebrate communities, with important consequences for ecosystem function, such as biomass production. We assessed: (1) the effects of experimental soil nutrient additions on invertebrate abundances and feeding rates and (2) the resultant changes in the effects of invertebrates on aboveground plant biomass at three grassland sites spanning the North American Central Plains, across which plant tissue chemistry and biomass vary. Invertebrate communities and rates of herbivory were sampled within a long-term nutrient-addition experiment established at each site along the broad Central Plains precipitation gradient. Additionally, the effects of invertebrates on aboveground plant biomass were determined under ambient and elevated nutrient conditions. At the more mesic sites, invertebrate herbivore abundances increased and their per capita rate of herbivory decreased with nutrient additions. In contrast, at the semi-arid site where plant biomass is low and plant nutrient concentrations are high, invertebrate herbivore abundances did not vary and per capita rates of herbivory increased with nutrient additions. No change in the effect of invertebrate herbivores on aboveground plant biomass was observed at any of the sites. In sum, nutrient additions induced shifts in both plant biomass and leaf nutrient content, which altered invertebrate abundances and feeding rate. However, due to the inverse relationship between changes in herbivore abundance and per capita rates of herbivory, nutrient additions did not alter the effect of invertebrates on aboveground biomass. Overall, we suggest that this inverse response of herbivore abundance and per capita feeding rate may buffer ecosystems against changes in invertebrate damage in response to fluctuations in nutrient levels.

  2. Site Environmental Report for 2004. Volume 1, Environment, Health, and Safety Division

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2005-09-30

    Each year, Ernest Orlando Lawrence Berkeley National Laboratory prepares an integrated report on its environmental programs to satisfy the requirements of United States Department of Energy Order 231.1A, Environment, Safety, and Health Reporting.1 The Site Environmental Report for 2004 summarizes Berkeley Lab’s environmental management performance, presents environmental monitoring results, and describes significant programs for calendar year 2004. (Throughout this report, Ernest Orlando Lawrence Berkeley National Laboratory is referred to as “Berkeley Lab,” “the Laboratory,” “Lawrence Berkeley National Laboratory,” and “LBNL.”) The report is separated into two volumes. Volume I contains an overview of the Laboratory, the status of environmental programs,more » and summarized results from surveillance and monitoring activities. Volume II contains individual data results from these activities. This year, the Site Environmental Report was distributed by releasing it on the Web from the Berkeley Lab Environmental Services Group (ESG) home page, which is located at http://www.lbl.gov/ehs/esg/. Many of the documents cited in this report also are accessible from the ESG Web page. CD and printed copies of this Site Environmental Report are available upon request.« less

  3. Nuclear power: Siting and safety

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Openshaw, S.

    1986-01-01

    By 2030, half, or even two-thirds, of all electricity may be generated by nuclear power. Major reactor accidents are still expected to be rare occurrences, but nuclear safety is largely a matter of faith. Terrorist attacks, sabotage, and human error could cause a significant accident. Reactor siting can offer an additional, design-independent margin of safety. Remote geographical sites for new plants would minimize health risks, protect the industry from negative changes in public opinion concerning nuclear energy, and improve long-term public acceptance of nuclear power. U.K. siting practices usually do not consider the contribution to safety that could be obtainedmore » from remote sites. This book discusses the present trends of siting policies of nuclear power and their design-independent margin of safety.« less

  4. Effect of Additional Incentives for Aviation Biofuels: Results from the Biomass Scenario Model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vimmerstedt, Laura J; Newes, Emily K

    2017-12-05

    The National Renewable Energy Laboratory supported the Department of Energy, Bioenergy Technologies Office, with analysis of alternative jet fuels in collaboration with the U.S. Department of Transportation, Federal Aviation Administration. Airlines for America requested additional exploratory scenarios within FAA analytic framework. Airlines for America requested additional analysis using the same analytic framework, the Biomass Scenario Model. The results were presented at a public working meeting of the California Air Resources Board on including alternative jet fuel in the Low Carbon Fuel Standard on March 17, 2017 (https://www.arb.ca.gov/fuels/lcfs/lcfs_meetings/lcfs_meetings.htm). This presentation clarifies and annotates the slides from the public working meeting, andmore » provides a link to the full data set. NREL does not advocate for or against the policies analyzed in this study.« less

  5. Effect of Additional Incentives for Aviation Biofuels: Results from the Biomass Scenario Model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vimmerstedt, Laura J; Newes, Emily K

    The National Renewable Energy Laboratory supported the Department of Energy, Bioenergy Technologies Office, with analysis of alternative jet fuels in collaboration with the U.S. Department of Transportation, Federal Aviation Administration. Airlines for America requested additional exploratory scenarios within FAA analytic framework. Airlines for America requested additional analysis using the same analytic framework, the Biomass Scenario Model. The results were presented at a public working meeting of the California Air Resources Board on including alternative jet fuel in the Low Carbon Fuel Standard on March 17, 2017 (https://www.arb.ca.gov/fuels/lcfs/lcfs_meetings/lcfs_meetings.htm). This presentation clarifies and annotates the slides from the public working meeting, andmore » provides a link to the full data set. NREL does not advocate for or against the policies analyzed in this study.« less

  6. 75 FR 32005 - National Emission Standards for Hazardous Air Pollutants for Major Sources: Industrial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-04

    ... Web site. E-mail: Comments may be sent by electronic mail (e-mail) to a-and-r[email protected] otherwise protected through http://www.regulations.gov or e-mail. The http://www.regulations.gov Web site is... Web site: http://www.epa.gov/airquality/combustion . Please refer to this Web site to confirm the date...

  7. Site clearance working group

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    The Gulf of Mexico and Louisiana continue to be areas with a high level of facility removal, and the pace of removal is projected to increase. Regulations were promulgated for the Gulf of Mexico and Louisiana requiring that abandoned sites be cleared of debris that could interfere with fishing and shrimping activities. The site clearance regulations also required verification that the sites were clear. Additionally, government programs were established to compensate fishermen for losses associated with snagging their equipment on oil and gas related objects that remained on the water bottoms in areas other than active producing sites and sitesmore » that had been verified as clear of obstructions and snags. The oil and gas industry funds the compensation programs. This paper reviews the regulations and evolving operating practices in the Gulf of Mexico and Louisiana where site clearance and fisherman`s gear compensation regulations have been in place for a number of years. Although regulations and guidelines may be in place elsewhere in the world, this paper focuses on the Gulf of Mexico and Louisiana. Workshop participants are encouraged to bring up international issues during the course of the workshop. Additionally, this paper raises questions and focuses on issues that are of concern to the various Gulf of Mexico and Louisiana water surface and water bottom stakeholders. This paper does not have answers to the questions or issues. During the workshop participants will debate the questions and issues in an attempt to develop consensus opinions and/or make suggestions that can be provided to the appropriate organizations, both private and government, for possible future research or policy adjustments. Site clearance and facility removal are different activities. Facility removal deals with removal of the structures used to produce oil and gas including platforms, wells, casing, piles, pipelines, well protection structures, etc.« less

  8. 76 FR 79656 - Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ... buildings, parks and memorials. Draft agendas and additional information regarding the Commission are available on our Web site: www.cfa.gov . Inquiries regarding the agenda and requests to submit written or... Filed 12-21-11; 8:45 am] BILLING CODE 6330-01-M ...

  9. 76 FR 27020 - National Climate Assessment and Development Advisory Committee (NCADAC); Notice of Open Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-10

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration National Climate Assessment... proposed agenda of a forthcoming meeting of the DoC NOAA National Climate Assessment and Development... Climate Assessment Web site for additional information at http://www.globalchange.gov/what-we-do...

  10. Refining the site conceptual model at a former uranium mill site in Riverton, Wyoming, USA

    DOE PAGES

    Dam, William; Campbell, Sam; Johnson, Ray; ...

    2015-07-07

    Milling activities at a former uranium mill site near Riverton, Wyoming, USA, contaminated the shallow groundwater beneath and downgradient of the site. Although the mill operated for <6 years (1958-1963), its impact remains an environmental liability. Groundwater modeling predicted that contaminant concentrations were declining steadily, which confirmed the conceptual site model (CSM). However, local flooding in 2010 mobilized contaminants that migrated downgradient from the Riverton site and resulted in a dramatic increase in groundwater contaminant concentrations. This observation indicated that the original CSM was inadequate to explain site conditions and needed to be refined. In response to the new observationsmore » after the flood, a collaborative investigation to better understand site conditions and processes commenced. This investigation included installing 103 boreholes to collect soil and groundwater samples, sampling and analysis of evaporite minerals along the bank of the Little Wind River, an analysis of evaportranspiration in the shallow aquifer, and sampling naturally organic-rich sediments near groundwater discharge areas. The enhanced characterization revealed that the existing CSM did not account for high uranium concentrations in groundwater remaining on the former mill site and groundwater plume stagnation near the Little Wind River. Observations from the flood and subsequent investigations indicate that additional characterization is still needed to continue refining the CSM and determine the viability of the natural flushing compliance strategy. Additional sampling, analysis, and testing of soil and groundwater are necessary to investigate secondary contaminant sources, mobilization of contaminants during floods, geochemical processes, contaminant plume stagnation, distribution of evaporite minerals and organic-rich sediments, and mechanisms and rates of contaminant transfer from soil to groundwater. Future data collection will be used to

  11. Middlesex FUSRAP Site - A Path to Site-Wide Closure - 13416

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Miller, David M.; Edge, Helen

    2013-07-01

    The road-map to obtaining closure of the Middlesex Sampling Plant FUSRAP site in Middlesex, New Jersey (NJ) has required a multi-faceted approach, following the CERCLA Process. Since 1998, the US ACE, ECC, and other contractors have completed much of the work required for regulatory acceptance of site closure with unrestricted use. To date, three buildings have been decontaminated, demolished, and disposed of. Two interim storage piles have been removed and disposed of, followed by the additional removal and disposal of over 87,000 tons of radiologically and chemically-impacted subsurface soils by the summer of 2008. The US ACE received a determinationmore » from the EPA for the soils Operable Unit, (OU)-1, in September 2010 that the remedial excavations were acceptable, and meet the criteria for unrestricted use as required by the 2004 Record of Decision (ROD) for OU-1. Following the completion of OU-1, the project delivery team performed additional field investigation of the final Operable Unit for Middlesex, OU-2, Groundwater. As of December 2012, the project delivery team has completed a Supplemental Remedial Investigation, which will be followed with a streamlined Feasibility Study, Proposed Plan, and ROD. Several years of historical groundwater data was available from previous investigations and the FUSRAP Environmental Surveillance Program. Historical data indicated sporadic detections of Volatile Organic Compounds (VOCs), primarily trichloroethylene (TCE), carbon tetrachloride (CT), and methyl tert-butyl ether (MTBE), with no apparent trend or pattern indicating extent or source of the VOC impact. In 2008, the project delivery team initiated efforts to re-assess the Conceptual Site Model (CSM) for groundwater. The bedrock was re-evaluated as a leaky multi-unit aquifer, and a plan was developed for additional investigations for adequate bedrock characterization and delineation of groundwater contaminated primarily by CT, TCE, and tetrachloroethene (PCE

  12. Oak Ridge Reservation annual site environmental report for 2008

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    none,

    2009-09-01

    The Oak Ridge Reservation (ORR) consists of three major government-owned, contractor-operated facilities: the Y-12 National Security Complex, Oak Ridge National Laboratory, and East Tennessee Technology Park. The ORR was established in the early 1940s as part of the Manhattan Project, a secret undertaking that produced materials for the first atomic bombs. The reservation’s role has evolved over the years, and it continues to adapt to meet the changing defense, energy, and research needs of the United States. Both the work carried out for the war effort and subsequent research, development, and production activities have involved, and continue to involve, themore » use of radiological and hazardous materials. The Oak Ridge Reservation Annual Site Environmental Report and supporting data are available at http://www.ornl.gov/sci/env_rpt or from the project director. This document is prepared annually to summarize environmental activities, primarily environmental monitoring activities, on the Oak Ridge Reservation (ORR) and within the ORR surroundings. The document fulfills the requirement of Department of Energy (DOE) Order 231.1A, Environment, Safety and Health Reporting, for an annual summary of environmental data to characterize environmental performance. The environmental monitoring criteria are described in DOE Order 450.1A, Environmental Protection Program. The results summarized in this report are based on data collected prior to and through 2008. This report is not intended to provide the results of all sampling on the ORR. Additional data collected for other site and regulatory purposes, such as environmental restoration/remedial investigation reports, waste management characterization sampling data, and environmental permit compliance data, are presented in other documents that have been prepared in accordance with applicable DOE guidance and/or laws and are referenced herein as appropriate. Corrections to the report for the previous year are found in

  13. Effect-site concentration of propofol required for LMA-Supreme™ insertion with and without remifentanil: a randomized controlled trial.

    PubMed

    Zaballos, Matilde; Bastida, Emilia; Agustí, Salomé; Portas, Maite; Jiménez, Consuelo; López-Gil, Maite

    2015-10-06

    A new supraglottic device, the LMA-Supreme™, has recently become available for clinical use. Information on anaesthetic and co-adjuvant requirements for insertion of the LMA-Supreme™ is limited. The present study aimed to evaluate the optimal effect-site concentration of propofol in 50 % (EC50) of adults necessary for successful insertion of the LMA-Supreme™ and to examine remifentanil's effect on propofol requirements. Fifty-eight elective patients (aged 18-60 years; ASA (American Society Anaesthesiologists) physical status classification I and II) scheduled for day surgery were randomly assigned to one of two groups: propofol with saline or propofol with remifentanil. Anaesthesia was induced by target-controlled infusion according to predetermined effect-site concentrations of propofol and remifentanil (5 ng.mL(-1)). The EC50 was calculated using Dixon's up-and-down method. Ten minutes following drug administration, LMA-Supreme™ insertion was attempted without the use of muscle relaxant drugs. In the propofol + saline group, the EC50 of propofol required for LMA-Supreme™ insertion was 6.32 ± 0.67 μg.mL(-1) (95 % CI, 5.69-6.94 μg.mL(-1)). With the addition of remifentanil at an effect-site concentration of 5 ng.mL(-1), the EC50 of propofol required for LMA-Supreme™ insertion was 2.50 ± 0.80 μg.mL(-1) (95 % CI, 1.82-3.17 μg.mL(-1); p < 0.0001). The propofol requirement for smooth insertion of the LMA-Supreme™ was 60 % less when remifentanil (5 ng.mL(-1)) was co-administered. Identified as NCT01974648 at www.clinicaltrials.gov .

  14. 75 FR 59322 - Notice of Availability of Answers to Frequently Asked Questions Regarding Buy America & FRA's...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-27

    ... Asked Questions can be found on FRA's Web site at http://www.fra.dot.gov/Pages/11.shtml . DATES: Written... electronic site at http://www.regulations.gov . Commenters should follow the instructions below for mailed and hand-delivered comments. (1) Web Site: http://www.regulations.gov . Follow the instructions for...

  15. Internet (WWW) based system of ultrasonic image processing tools for remote image analysis.

    PubMed

    Zeng, Hong; Fei, Ding-Yu; Fu, Cai-Ting; Kraft, Kenneth A

    2003-07-01

    Ultrasonic Doppler color imaging can provide anatomic information and simultaneously render flow information within blood vessels for diagnostic purpose. Many researchers are currently developing ultrasound image processing algorithms in order to provide physicians with accurate clinical parameters from the images. Because researchers use a variety of computer languages and work on different computer platforms to implement their algorithms, it is difficult for other researchers and physicians to access those programs. A system has been developed using World Wide Web (WWW) technologies and HTTP communication protocols to publish our ultrasonic Angle Independent Doppler Color Image (AIDCI) processing algorithm and several general measurement tools on the Internet, where authorized researchers and physicians can easily access the program using web browsers to carry out remote analysis of their local ultrasonic images or images provided from the database. In order to overcome potential incompatibility between programs and users' computer platforms, ActiveX technology was used in this project. The technique developed may also be used for other research fields.

  16. Identification of site frequencies from building records

    USGS Publications Warehouse

    Celebi, M.

    2003-01-01

    A simple procedure to identify site frequencies using earthquake response records from roofs and basements of buildings is presented. For this purpose, data from five different buildings are analyzed using only spectral analyses techniques. Additional data such as free-field records in close proximity to the buildings and site characterization data are also used to estimate site frequencies and thereby to provide convincing evidence and confirmation of the site frequencies inferred from the building records. Furthermore, simple code-formula is used to calculate site frequencies and compare them with the identified site frequencies from records. Results show that the simple procedure is effective in identification of site frequencies and provides relatively reliable estimates of site frequencies when compared with other methods. Therefore the simple procedure for estimating site frequencies using earthquake records can be useful in adding to the database of site frequencies. Such databases can be used to better estimate site frequencies of those sites with similar geological structures.

  17. Manipulating crystallization with molecular additives.

    PubMed

    Shtukenberg, Alexander G; Lee, Stephanie S; Kahr, Bart; Ward, Michael D

    2014-01-01

    Given the importance of organic crystals in a wide range of industrial applications, the chemistry, biology, materials science, and chemical engineering communities have focused considerable attention on developing methods to control crystal structure, size, shape, and orientation. Tailored additives have been used to control crystallization to great effect, presumably by selectively binding to particular crystallographic surfaces and sites. However, substantial knowledge gaps still exist in the fundamental mechanisms that govern the formation and growth of organic crystals in both the absence and presence of additives. In this review, we highlight research discoveries that reveal the role of additives, either introduced by design or present adventitiously, on various stages of formation and growth of organic crystals, including nucleation, dislocation spiral growth mechanisms, growth inhibition, and nonclassical crystal morphologies. The insights from these investigations and others of their kind are likely to guide the development of innovative methods to manipulate crystallization for a wide range of materials and applications.

  18. Site observational work plan for the UMTRA Project site at Monument Valley, Arizona

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1995-09-01

    The site observational work plan (SOWP) for the Monument Valley, Arizona, US Department of Energy (DOE) Uranium Mill Tailings Remedial Action (UMTRA) Project site is one of the first site-specific documents developed to achieve ground water compliance at the site. This SOWP applies information about the Monument Valley site to a regulatory compliance framework that identifies strategies that could be used to meet ground water compliance. The compliance framework was developed in the UMTRA Ground Water programmatic environmental impact statement (DOE, 1995). The DOE`s goal is to implement a cost-effective site strategy that complies with the US Environmental Protection Agencymore » (EPA) ground water standards and protects human health and the environment. The compliance strategy that emerges in the final version of the SOWP will assess potential environmental impacts and provide stakeholder a forum for review and comment. When the compliance strategy is acceptable, it will be detailed in a remedial action plan that will be subject to review by the state and/or tribe and concurrence by the US Nuclear Regulatory Commission (NRC). Information available for the preparation of this SOWP indicates active remediation is the most likely compliance strategy for the Monument Valley site. Additional data are needed to determine the most effective remediation technology.« less

  19. A novel classification and online platform for planning and documentation of medical applications of additive manufacturing.

    PubMed

    Tuomi, Jukka; Paloheimo, Kaija-Stiina; Vehviläinen, Juho; Björkstrand, Roy; Salmi, Mika; Huotilainen, Eero; Kontio, Risto; Rouse, Stephen; Gibson, Ian; Mäkitie, Antti A

    2014-12-01

    Additive manufacturing technologies are widely used in industrial settings and now increasingly also in several areas of medicine. Various techniques and numerous types of materials are used for these applications. There is a clear need to unify and harmonize the patterns of their use worldwide. We present a 5-class system to aid planning of these applications and related scientific work as well as communication between various actors involved in this field. An online, matrix-based platform and a database were developed for planning and documentation of various solutions. This platform will help the medical community to structurally develop both research innovations and clinical applications of additive manufacturing. The online platform can be accessed through http://www.medicalam.info. © The Author(s) 2014.

  20. A web site for calculating the degree of chirality.

    PubMed

    Zayit, Amir; Pinsky, Mark; Elgavi, Hadassah; Dryzun, Chaim; Avnir, David

    2011-01-01

    The web site, http://www.csm.huji.ac.il/, uses the Continuous Chirality Measure to evaluate quantitatively the degree of chirality of a molecule, a structure, a fragment. The value of this measure ranges from zero, the molecule is achiral, to higher values (the upper limit is 100); the higher the chirality value, the more chiral the molecule is. The measure is based on the distance between the chiral molecule and the nearest structure that is achiral. Questions such as the following can be addressed: by how much is one molecule more chiral than the other? how does chirality change along conformational motions? is there a correlation between chirality and enantioselectivity in a series of molecules? Both elementary and advanced features are offered. Related calculation options are the symmetry measures and shape measures. Copyright © 2009 Wiley-Liss, Inc.

  1. The Oak Ridge Reservation Annual Site Environmental Report, 2007

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hughes, Joan; Thompson, Sharon; Page, David

    2008-09-30

    The Oak Ridge Reservation (ORR) consists of three major government-owned, contractor-operated facilities: the Y-12 National Security Complex, Oak Ridge National Laboratory, and East Tennessee Technology Park. The ORR was established in the early 1940s as part of the Manhattan Project, a secret undertaking that produced materials for the first atomic bombs. The reservation’s role has evolved over the years, and it continues to adapt to meet the changing defense, energy, and research needs of the United States. Both the work carried out for the war effort and subsequent research, development, and production activities have involved, and continue to involve, themore » use of radiological and hazardous materials. The Oak Ridge Reservation Annual Site Environmental Report and supporting data are available at Http://www.ornl.gov/sci/env_rpt or from the project director.« less

  2. 78 FR 14776 - Federal Perkins Loan, Federal Work-Study, and Federal Supplemental Educational Opportunity Grant...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-07

    ... for Financial Aid Professionals (IFAP) Web site at: www.ifap.ed.gov . Deadline Dates: The following... site at www.cbfisap.ed.gov . 2. The 2012-2013 Fiscal Operations Report The FISAP must be submitted... the eCampus-Based Web site at www.cbfisap.ed.gov . The FISAP signature page must be mailed to: FISAP...

  3. 75 FR 31937 - Standards of Performance for New Stationary Sources and Emission Guidelines for Existing Sources...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-04

    ...-and-r[email protected] , Attention Docket ID No. EPA-HQ-OAR-2003-0119. Facsimile: Fax your comments to... otherwise protected through http://www.regulations.gov or e-mail. The http://www.regulations.gov Web site is... following Web site: http://www.epa.gov/airquality/combustion . Please refer to this Web site to confirm the...

  4. Report on July 2015 Additional Protocol Coordinators Best Practices Workshop

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gitau, Ernest T.N.; Burbank, Roberta L.; Finch, Valerie A.

    After 10 years of implementation experience, the Office of Nonproliferation and Arms Control (NPAC) within the Department of Energy/National Nuclear Security Administration (DOE/NNSA) conducted the Additional Protocol (AP) Coordinators Best Practices Workshop at Oak Ridge National Laboratory from July 29-30, 2015. The goal of this workshop was to identify implementation best practices, lessons learned, and compliance challenges from the various Additional Protocol Coordinators (APCs) at each laboratory in the DOE/NNSA complex and associated sites. The workshop provided the opportunity for participants to share their insights and establish networks that APCs can utilize to continue to discuss challenges (new and old),more » identify best practices, and enhance communication and coordination for reporting multi-lab research projects during review activities. Workshop participants included DOE/NNSA HQ, laboratory and site APCs, seasoned experts, members of the original implementation outreach team, and Field Element and site security representatives.« less

  5. 77 FR 35430 - National Science Board; Sunshine Act Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-13

    ... Board's Committee on Science and Engineering Indicators, pursuant to NSF regulations (45 CFR part 614... policy Companion to Science and Engineering Indicators 2012 on the topic of state funding of public... National Science Board Web site www.nsf.gov/nsb for additional information and schedule updates (time...

  6. 75 FR 54882 - Submission of information collection for approval From the Office of Management and Budget

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ... Floor, 1700 G Street, NW., Washington, DC 20552. We will post all public comments we receive without... site at http://www.fhfa.gov . In addition, copies of all comments received will be available for... supporting documentation, contact Charles McLean, Associate Director, Office of Housing and Community...

  7. 31 CFR 541.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[ZIMBABWE].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining...

  8. 31 CFR 541.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[ZIMBABWE].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining...

  9. 31 CFR 541.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[ZIMBABWE].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining...

  10. 31 CFR 541.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[ZIMBABWE].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining...

  11. 76 FR 28224 - Science Advisory Board Staff Office; Notification of a Public Teleconference of the Science...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-16

    ... Advisory Board can be found at the EPA SAB Web site at http://www.epa.gov/sab . SUPPLEMENTARY INFORMATION..., and human health effects. The Deep Water Horizon spill identified the need for additional research on alternative spill response technologies; environmental impacts of chemical dispersants under deep sea...

  12. Addition of a breeding database in the Genome Database for Rosaceae.

    PubMed

    Evans, Kate; Jung, Sook; Lee, Taein; Brutcher, Lisa; Cho, Ilhyung; Peace, Cameron; Main, Dorrie

    2013-01-01

    Breeding programs produce large datasets that require efficient management systems to keep track of performance, pedigree, geographical and image-based data. With the development of DNA-based screening technologies, more breeding programs perform genotyping in addition to phenotyping for performance evaluation. The integration of breeding data with other genomic and genetic data is instrumental for the refinement of marker-assisted breeding tools, enhances genetic understanding of important crop traits and maximizes access and utility by crop breeders and allied scientists. Development of new infrastructure in the Genome Database for Rosaceae (GDR) was designed and implemented to enable secure and efficient storage, management and analysis of large datasets from the Washington State University apple breeding program and subsequently expanded to fit datasets from other Rosaceae breeders. The infrastructure was built using the software Chado and Drupal, making use of the Natural Diversity module to accommodate large-scale phenotypic and genotypic data. Breeders can search accessions within the GDR to identify individuals with specific trait combinations. Results from Search by Parentage lists individuals with parents in common and results from Individual Variety pages link to all data available on each chosen individual including pedigree, phenotypic and genotypic information. Genotypic data are searchable by markers and alleles; results are linked to other pages in the GDR to enable the user to access tools such as GBrowse and CMap. This breeding database provides users with the opportunity to search datasets in a fully targeted manner and retrieve and compare performance data from multiple selections, years and sites, and to output the data needed for variety release publications and patent applications. The breeding database facilitates efficient program management. Storing publicly available breeding data in a database together with genomic and genetic data will

  13. Facility siting as a decision process at the Savannah River Site

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wike, L.D.

    1995-12-31

    Site selection for new facilities at Savannah River Site (SRS) historically has been a process dependent only upon specific requirements of the facility. While this approach is normally well suited to engineering and operational concerns, it can have serious deficiencies in the modern era of regulatory oversight and compliance requirements. There are many issues related to the site selection for a facility that are not directly related to engineering or operational requirements; such environmental concerns can cause large schedule delays and budget impact,s thereby slowing or stopping the progress of a project. Some of the many concerns in locating amore » facility include: waste site avoidance, National Environmental Policy Act requirements, Clean Water Act, Clean Air Act, wetlands conservation, US Army Corps of Engineers considerations, US Fish and Wildlife Service statutes including threatened and endangered species issues, and State of South Carolina regulations, especially those of the Department of Health and Environmental Control. In addition, there are SRS restrictions on research areas set aside for National Environmental Research Park (NERP), Savannah River Ecology Laboratory, Savannah River Forest Station, University of South Carolina Institute of Archaeology and Anthropology, Southeastern Forest Experimental Station, and Savannah River Technology Center (SRTC) programs. As with facility operational needs, all of these siting considerations do not have equal importance. The purpose of this document is to review recent site selection exercises conducted for a variety of proposed facilities, develop the logic and basis for the methods employed, and standardize the process and terminology for future site selection efforts.« less

  14. SITE CHARACTERIZATION LIBRARY: VOLUMN 1 (RELEASE 2.5)

    EPA Science Inventory

    This CD-ROM, Volume 1, Release 2.5, of EPA's National Exposure Research Laboratory (NERL - Las Vegas) Site Characterization Library, contains additional electronic documents and computer programs related to the characterization of hazardous waste sites. EPA has produced this libr...

  15. Quantifying site-specific physical heterogeneity within an estuarine seascape

    USGS Publications Warehouse

    Kennedy, Cristina G.; Mather, Martha E.; Smith, Joseph M.

    2017-01-01

    Quantifying physical heterogeneity is essential for meaningful ecological research and effective resource management. Spatial patterns of multiple, co-occurring physical features are rarely quantified across a seascape because of methodological challenges. Here, we identified approaches that measured total site-specific heterogeneity, an often overlooked aspect of estuarine ecosystems. Specifically, we examined 23 metrics that quantified four types of common physical features: (1) river and creek confluences, (2) bathymetric variation including underwater drop-offs, (3) land features such as islands/sandbars, and (4) major underwater channel networks. Our research at 40 sites throughout Plum Island Estuary (PIE) provided solutions to two problems. The first problem was that individual metrics that measured heterogeneity of a single physical feature showed different regional patterns. We solved this first problem by combining multiple metrics for a single feature using a within-physical feature cluster analysis. With this approach, we identified sites with four different types of confluences and three different types of underwater drop-offs. The second problem was that when multiple physical features co-occurred, new patterns of total site-specific heterogeneity were created across the seascape. This pattern of total heterogeneity has potential ecological relevance to structure-oriented predators. To address this second problem, we identified sites with similar types of total physical heterogeneity using an across-physical feature cluster analysis. Then, we calculated an additive heterogeneity index, which integrated all physical features at a site. Finally, we tested if site-specific additive heterogeneity index values differed for across-physical feature clusters. In PIE, the sites with the highest additive heterogeneity index values were clustered together and corresponded to sites where a fish predator, adult striped bass (Morone saxatilis), aggregated in a

  16. SPECTRE (www.noveltis.fr/spectre): a web Service for Ionospheric Products

    NASA Astrophysics Data System (ADS)

    Jeansou, E.; Crespon, F.; Garcia, R.; Helbert, J.; Moreaux, G.; Lognonne, P.

    2005-12-01

    The dense GPS networks developed for geodesic applications appear to be very efficient ionospheric sensors because of interaction between plasma and electromagnetic waves. Indeed, the dual frequency receivers provide data from which the Slant Total Electron Content (STEC) can be easily extracted to compute Vertical Total Electron Content (VTEC) maps. The SPECTRE project, Service and Products for ionospheric Electron Content and Tropospheric Refractivity over Europe, is currently a pre-operational service providing VTEC maps with high time and space resolution after 3 days time delay (http://www.noveltis.fr/spectre and http://ganymede.ipgp.jussieu.fr/spectre). This project is a part of SWENET, SpaceWeather European Network, initiated by the European Space Agency. The SPECTRE data products are useful for many applications. We will present these applications in term of interest for the scientific community with a special focus on spaceweather and transient ionospheric perturbations related to Earthquakes. Moreover, the pre-operational extensions of SPECTRE to the californian (SCIGN/BARD) and japanese (GEONET) dense GPS networks will be presented. Then the method of 3D tomography of the electron density from GPS data will be presented and its resolution discussed. The expected improvements of the 3D tomographic images by new tomographic reconstruction algorithms and by the advent of the Galileo system will conclude the presentation.

  17. Implications of NGA for NEHRP site coefficients

    USGS Publications Warehouse

    Borcherdt, Roger D.

    2012-01-01

    Three proposals are provided to update tables 11.4-1 and 11.4-2 of Minimum Design Loads for Buildings and Other Structures (7-10), by the American Society of Civil Engineers (2010) (ASCE/SEI 7-10), with site coefficients implied directly by NGA (Next Generation Attenuation) ground motion prediction equations (GMPEs). Proposals include a recommendation to use straight-line interpolation to infer site coefficients at intermediate values of ̅vs (average shear velocity). Site coefficients are recommended to ensure consistency with ASCE/SEI 7-10 MCER (Maximum Considered Earthquake) seismic-design maps and simplified site-specific design spectra procedures requiring site classes with associated tabulated site coefficients and a reference site class with unity site coefficients. Recommended site coefficients are confirmed by independent observations of average site amplification coefficients inferred with respect to an average ground condition consistent with that used for the MCER maps. The NGA coefficients recommended for consideration are implied directly by the NGA GMPEs and do not require introduction of additional models.

  18. Pursestring closure of the stoma site leads to fewer wound infections: results from a multicenter randomized controlled trial.

    PubMed

    Lee, Janet T; Marquez, Thao T; Clerc, Daniel; Gie, Olivier; Demartines, Nicolas; Madoff, Robert D; Rothenberger, David A; Christoforidis, Dimitrios

    2014-11-01

    Surgical site infection after stoma reversal is common. The optimal skin closure technique after stoma reversal has been widely debated in the literature. We hypothesized that pursestring near-complete closure of the stoma site would lead to fewer surgical site infections compared with conventional primary closure. This study was a parallel prospective multicenter randomized controlled trial. This study was conducted at 2 university medical centers. Patients (N = 122) presenting for elective colostomy or ileostomy reversal were selected. Pursestring versus conventional primary closure of stoma sites were compared. Stoma site surgical site infection within 30 days of surgery, overall surgical site infection, delayed healing (open wound for >30 days), time to wound epithelialization, and patient satisfaction were the primary outcomes measured. The pursestring group had a significantly lower stoma site infection rate (2% vs 15%, p = 0.01). There was no difference in delayed healing or patient satisfaction between groups. Time to epithelialization was measured in only 51 patients but was significantly longer in the pursestring group (34.6 ± 20 days vs 24.1 ± 17 days, p = 0.02). This study was limited by the variability in procedures and surgeons, the limited follow-up after 30 days, and the inability to perform blinding. Pursestring closure after stoma reversal has a lower risk of stoma site surgical site infection than conventional primary closure, although wounds may take longer to heal with the use of this approach. NCT01713452 (www.clinicaltrials.gov).

  19. Arsenic Remediation Enhancement Through Chemical Additions to Pump and Treat Operations

    NASA Astrophysics Data System (ADS)

    Wovkulich, K.; Mailloux, B. J.; Stute, M.; Simpson, H. J.; Keimowitz, A. R.; Powell, A.; Lacko, A.; Chillrud, S. N.

    2008-12-01

    Arsenic is a contaminant found at more than 500 US Superfund sites. Since pump and treat technologies are widely used for remediation of contaminated groundwater, increasing the efficiency of contaminant removal at such sites should allow limited financial resources to clean up more sites. The Vineland Chemical Company Superfund site is extensively contaminated with arsenic after waste arsenic salts were stored and disposed of improperly for much of the company's 44 year manufacturing lifetime. Despite approximately eight years of pump and treat remediation, arsenic concentrations in the recovery wells can still be greater than 1000 ppb. The arsenic concentrations in the groundwater remain high because of slow desorption of arsenic from contaminated aquifer solids. Extrapolation of laboratory column experiments suggest that continuing the current groundwater remediation practice based on flushing ambient groundwater through the system may require on the order of hundreds of years to clean the site. However, chemical additions of phosphate or oxalic acid into the aquifer could decrease the remediation time scale substantially. Laboratory results from a soil column experiment using input of 10 mM oxalic acid suggest that site clean up of groundwater could be decreased to as little as four years. Pilot scale forced gradient field experiments will help establish whether chemical additions can be effective for increasing arsenic mobilization from aquifer solids and thus substantially decrease pump and treat clean up time.

  20. 40 CFR 228.6 - Specific criteria for site selection.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Specific criteria for site selection... selection. (a) In the selection of disposal sites, in addition to other necessary or appropriate factors...) Existence at or in close proximity to the site of any significant natural or cultural features of historical...

  1. Perceptions of Business Students' Feature Requirements in Educational Web Sites

    ERIC Educational Resources Information Center

    Hazari, Sunil; Johnson, Barbara

    2007-01-01

    There is paucity of original research that explains phenomena related to content organization and site design of educational Web sites. Educational Web sites are often used to provide Web-based instruction, which itself is a relatively recent phenomenon for business schools, and additional research is needed in this area. Educational Web sites are…

  2. Factors Associated With Time to Site Activation, Randomization, and Enrollment Performance in a Stroke Prevention Trial.

    PubMed

    Demaerschalk, Bart M; Brown, Robert D; Roubin, Gary S; Howard, Virginia J; Cesko, Eldina; Barrett, Kevin M; Longbottom, Mary E; Voeks, Jenifer H; Chaturvedi, Seemant; Brott, Thomas G; Lal, Brajesh K; Meschia, James F; Howard, George

    2017-09-01

    Multicenter clinical trials attempt to select sites that can move rapidly to randomization and enroll sufficient numbers of patients. However, there are few assessments of the success of site selection. In the CREST-2 (Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trials), we assess factors associated with the time between site selection and authorization to randomize, the time between authorization to randomize and the first randomization, and the average number of randomizations per site per month. Potential factors included characteristics of the site, specialty of the principal investigator, and site type. For 147 sites, the median time between site selection to authorization to randomize was 9.9 months (interquartile range, 7.7, 12.4), and factors associated with early site activation were not identified. The median time between authorization to randomize and a randomization was 4.6 months (interquartile range, 2.6, 10.5). Sites with authorization to randomize in only the carotid endarterectomy study were slower to randomize, and other factors examined were not significantly associated with time-to-randomization. The recruitment rate was 0.26 (95% confidence interval, 0.23-0.28) patients per site per month. By univariate analysis, factors associated with faster recruitment were authorization to randomize in both trials, principal investigator specialties of interventional radiology and cardiology, pre-trial reported performance >50 carotid angioplasty and stenting procedures per year, status in the top half of recruitment in the CREST trial, and classification as a private health facility. Participation in StrokeNet was associated with slower recruitment as compared with the non-StrokeNet sites. Overall, selection of sites with high enrollment rates will likely require customization to align the sites selected to the factor under study in the trial. URL: http://www.clinicaltrials.gov. Unique identifier: NCT02089217. © 2017

  3. Addition Chains: A reSolve Lesson

    ERIC Educational Resources Information Center

    Turner, Paul; Thornton, Steve

    2017-01-01

    This article draws on some ideas explored during and after a writing workshop to develop classroom resources for the reSolve: Mathematics by Inquiry (www.resolve.edu.au) project. The project develops classroom and professional learning resources that will promote a spirit of inquiry in school mathematics from Foundation to year ten. The…

  4. The role of forest site in fertilizer response

    Treesearch

    Raymond E. Leonard; Albert L. Leaf; John V. Berglund; John V. Berglund

    1972-01-01

    A major task in developing a successful forest-fertilization program is the proper assessment of the site conditions and organism relations so that efficient site-dependent fertilizer prescriptions may be developed for the most effective and least wasteful use of fertilizer additives.

  5. The relation between social network site usage and loneliness and mental health in community-dwelling older adults.

    PubMed

    Aarts, S; Peek, S T M; Wouters, E J M

    2015-09-01

    Loneliness is expected to become an even bigger social problem in the upcoming decades, because of the growing number of older adults. It has been argued that the use of social network sites can aid in decreasing loneliness and improving mental health. The purpose of this study was to examine whether and how social network sites usage is related to loneliness and mental health in community-dwelling older adults. The study population included community-dwelling older adults aged 60 and over residing in the Netherlands (n = 626) collected through the LISS panel (www.lissdata.nl). Univariate and multivariate linear regression analyses, adjusted for potentially important confounders, were conducted in order to investigate the relation between social network sites usage and (emotional and social) loneliness and mental health. More than half of the individuals (56.2%) reported to use social network sites at least several times per week. Social network sites usage appeared unrelated to loneliness in general, and to emotional and social loneliness in particular. Social network sites usage also appeared unrelated to mental health. Several significant associations between related factors and the outcomes at hand were detected. In this sample, which was representative for the Dutch population, social network sites usage was unrelated to loneliness and/or mental health. The results indicate that a simple association between social network site usage and loneliness and mental health as such, cannot automatically be assumed in community-dwelling older adults. Copyright © 2014 John Wiley & Sons, Ltd.

  6. Improving Strategies to Prevent and Prepare for Radiological Attack

    DTIC Science & Technology

    2010-03-01

    minimum 0.75% of available grant funding. Additionally, American Samoa, Guam, the Northern Mariana Islands, and the U.S. Virgin Islands each receive a...and Florida offer tax holidays on hurricane readiness supplies. The government should consider additional incentives to promote readiness. One...Taxation. “May Sales Tax Holiday : Hurricane and Emergency Preparedness Equipment.” Virginia Department of Taxation Web site http://www.tax.virginia.gov

  7. Pinellas County, Florida, Site Environmental Restoration Project Sitewide Environmental Monitoring Semiannual Progress Report for the Young - Rainey STAR Center June Through November 2016, January 2017

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Surovchak, Scott; Daniel, Joe

    The Young - Rainey STAR Center (Science, Technology, and Research Center) at the Pinellas County, Florida, Site is a former U.S. Department of Energy (DOE) facility constructed in the mid-1950s. The 96-acre STAR Center is located in Largo, Florida, and lies in the northeast quarter of Section 13, Township 30 South, Range 15 East (Figure 1). While it was owned by DOE, the purpose of the site was to develop and manufacture components for the nation’s nuclear weapons program. In 1987, the U.S. Environmental Protection Agency (EPA) performed a Resource Conservation and Recovery Act Facility Assessment (EPA 1988) at themore » site to gather information on potential releases of hazardous materials. In February of 1990, EPA issued a Hazardous and Solid Waste Amendments permit to DOE, requiring DOE to investigate and perform remediation activities in those areas designated as solid-waste management units (SWMUs) contaminated by hazardous materials resulting from DOE operations. A total of 17 SWMUs were identified and investigated at the STAR Center. By 1997, 13 of the 17 SWMUs had been remediated or approved for no further action. More recently, the Florida Department of Environmental Protection (FDEP) executed Conditional Site Rehabilitation Completion Orders for the Northeast Site and the Wastewater Neutralization Area on July 27, 2016, stating that no further action is required for those SWMUs. The Building 100 Area (a combination of the Old Drum Storage Site and the Building 100-Industrial Drain Leaks SWMUs) comprises the only two active SWMUs at the STAR Center (Figure 2). This document serves as the semiannual progress report for the SWMUs by providing the results of recent monitoring activities and a summary of ongoing and projected work. The STAR Center is owned by the Pinellas County Industrial Development Authority, but DOE is responsible for remediation activities at the site. Additional background information for the site is contained in the Long

  8. 77 FR 35430 - National Science Board; Sunshine Act Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-13

    ... Board's Committee on Science and Engineering Indicators, pursuant to NSF regulations (45 CFR part 614... policy Companion to Science and Engineering Indicators 2012 on the topic of state funding of public... refer to the National Science Board Web site www.nsf.gov/nsb for additional information and schedule...

  9. 75 FR 3210 - Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... scheduled for 21 January 2010, at 10 a.m. in the Commission offices at the National Building Museum, Suite... buildings, parks and memorials. Draft agendas and additional information regarding the Commission are available on our Web site: http://www.cfa.gov . Inquiries regarding the agenda and requests to submit...

  10. 78 FR 6813 - Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-31

    ... scheduled for 21 February 2013, at 10:00 a.m. in the Commission offices at the National Building Museum... include buildings, parks, and memorials. Draft agendas and additional information regarding the Commission are available on our Web site: www.cfa.gov . Inquiries regarding the agenda and requests to submit...

  11. 31 CFR 537.201 - Prohibited transactions involving certain blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[BURMA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the...

  12. 31 CFR 562.201 - Prohibited transactions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... the Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[IRAN-HR].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information...

  13. 31 CFR 562.201 - Prohibited transactions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[IRAN-HR].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information...

  14. 31 CFR 589.201 - Prohibited transactions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Register and incorporated into OFAC's Specially Designated Nationals and Blocked Persons List (“SDN List”) and appear with the prefix “UKRAINE” in the program tag associated with each listing. The SDN List is accessible through the following page on OFAC's Web site: www.treasury.gov/sdn. Additional information...

  15. 31 CFR 544.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[NPWMD].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the...

  16. 31 CFR 544.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[NPWMD].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the...

  17. 31 CFR 544.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[NPWMD].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the...

  18. 31 CFR 562.201 - Prohibited transactions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... the Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[IRAN-HR].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information...

  19. 31 CFR 537.201 - Prohibited transactions involving certain blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[BURMA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the...

  20. 31 CFR 595.311 - Specially designated terrorist.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[SDT].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the...

  1. 31 CFR 562.201 - Prohibited transactions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[IRAN-HR].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information...

  2. 31 CFR 537.201 - Prohibited transactions involving certain blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[BURMA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the...

  3. 31 CFR 544.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[NPWMD].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the...

  4. 31 CFR 595.311 - Specially designated terrorist.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Office of Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[SDT].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the...

  5. 77 FR 981 - Changes To Implement the Inventor's Oath or Declaration Provisions of the Leahy-Smith America...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-06

    ... are signing the oath or declaration, the joint inventors must sign the oath or declaration on behalf... be received on or before March 6, 2012. ADDRESSES: Comments should be sent be electronic mail message... Portal Web site ( http://www.regulations.gov ) for additional instructions on providing comments via the...

  6. 77 FR 64490 - North Pacific Fishery Management Council (NPFMC); Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-22

    ... Building at 700 West 9th Street, Juneau, AK. Council address: North Pacific Fishery Management Council, 605... will be required to enter the Federal Building in Juneau. Foreign nationals wishing to attend this... Federal Building in Juneau. Additional information is posted on the Council Web site: http://www...

  7. Promoting Evidence-Based Practices: New Teaching Module for Early Childhood Teacher Educators

    ERIC Educational Resources Information Center

    Young Children, 2009

    2009-01-01

    Linda Halgunseth, head of NAEYC's Office of Applied Research (OAR), tells readers about Child Care and Early Education Research Connections, a Web site (www.researchconnections.org/teaching_modules) to help teacher educators integrate knowledge about evidence-based practices into teacher education programs. In addition, the article touts the…

  8. 7 CFR 3411.4 - How to apply for a grant.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... funding opportunities Web site (http://www.grants.gov) as early as practicable each fiscal year. It will... and will be as complete as possible with respect to: (1) Descriptions of the specific research areas..., highly technical words or phraseology should be avoided where possible. In addition, phrases such as...

  9. CHARACTERIZING SITE HYDROLOGY (REGION 5)

    EPA Science Inventory

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  10. Using Publishers' Web Sites for Reference Collection Development.

    ERIC Educational Resources Information Center

    Holmberg, Melissa

    2000-01-01

    Analyzes the ways publishers' Web sites can be used by librarians to locate additional science and technology reference materials which fall within budget constraints while meeting the needs of the patrons. Reviews specific publishers' Web sites to compare features and show how they differ. (Author/LRW)

  11. Hanford Site Waste Management Units Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shearer, Jeffrey P.

    2012-02-29

    The Hanford Site Waste Management Units Report (HSWMUR) has been created to meet the requirements of the Tri-Party Agreement (TPA) Action Plan, Section 3.5, which states: “The Hanford Site Waste Management Units Report shall be generated, in a format agreed upon by the Parties, as a calendar year report and issued annually by the DOE by the end of February of each year, and posted electronically for regulator and public access. This report shall reflect all changes made in waste management unit status during the previous year.” This February 2012 version of the HSWMUR contains a comprehensive inventory of themore » 3389 sites and 540 subsites in the Waste Information Data System (WIDS). The information for each site contains a description of each unit and the waste it contains, where applicable. The WIDS database provides additional information concerning the sites contained in this report and is maintained with daily changes to these sites.« less

  12. Hanford Site Waste Management Units Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shearer, Jeffrey P.

    2014-02-19

    The Hanford Site Waste Management Units Report (HSWMUR) has been created to meet the requirements of the Tri-Party Agreement (TPA) Action Plan, Section 3.5, which states: “The Hanford Site Waste Management Units Report shall be generated, in a format agreed upon by the Parties, as a calendar year report and issued annually by the DOE by the end of February of each year, and posted electronically for regulator and public access. This report shall reflect all changes made in waste management unit status during the previous year.” This February 2013 version of the HSWMUR contains a comprehensive inventory of themore » 3438 sites and 569 subsites in the Waste Information Data System (WIDS). The information for each site contains a description of each unit and the waste it contains, where applicable. The WIDS database provides additional information concerning the sites contained in this report and is maintained with daily changes to these sites.« less

  13. Hanford Site Waste Management Units Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shearer, Jeffrey P.

    2013-02-13

    The Hanford Site Waste Management Units Report (HSWMUR) has been created to meet the requirements of the Tri-Party Agreement (TPA) Action Plan, Section 3.5, which states: “The Hanford Site Waste Management Units Report shall be generated, in a format agreed upon by the Parties, as a calendar year report and issued annually by the DOE by the end of February of each year, and posted electronically for regulator and public access. This report shall reflect all changes made in waste management unit status during the previous year.” This February 2013 version of the HSWMUR contains a comprehensive inventory of themore » 3427 sites and 564 subsites in the Waste Information Data System (WIDS). The information for each site contains a description of each unit and the waste it contains, where applicable. The WIDS database provides additional information concerning the sites contained in this report and is maintained with daily changes to these sites.« less

  14. CavityPlus: a web server for protein cavity detection with pharmacophore modelling, allosteric site identification and covalent ligand binding ability prediction.

    PubMed

    Xu, Youjun; Wang, Shiwei; Hu, Qiwan; Gao, Shuaishi; Ma, Xiaomin; Zhang, Weilin; Shen, Yihang; Chen, Fangjin; Lai, Luhua; Pei, Jianfeng

    2018-05-10

    CavityPlus is a web server that offers protein cavity detection and various functional analyses. Using protein three-dimensional structural information as the input, CavityPlus applies CAVITY to detect potential binding sites on the surface of a given protein structure and rank them based on ligandability and druggability scores. These potential binding sites can be further analysed using three submodules, CavPharmer, CorrSite, and CovCys. CavPharmer uses a receptor-based pharmacophore modelling program, Pocket, to automatically extract pharmacophore features within cavities. CorrSite identifies potential allosteric ligand-binding sites based on motion correlation analyses between cavities. CovCys automatically detects druggable cysteine residues, which is especially useful to identify novel binding sites for designing covalent allosteric ligands. Overall, CavityPlus provides an integrated platform for analysing comprehensive properties of protein binding cavities. Such analyses are useful for many aspects of drug design and discovery, including target selection and identification, virtual screening, de novo drug design, and allosteric and covalent-binding drug design. The CavityPlus web server is freely available at http://repharma.pku.edu.cn/cavityplus or http://www.pkumdl.cn/cavityplus.

  15. Effects of Molybdenum Addition on Hydrogen Desorption of TiC Precipitation-Hardened Steel

    NASA Astrophysics Data System (ADS)

    Song, Eun Ju; Baek, Seung-Wook; Nahm, Seung Hoon; Suh, Dong-Woo

    2018-05-01

    The hydrogen-trap states in TiC and MoC that have coherent interfaces with ferrite were investigated using first-principles calculation. The trapping sites of TiC were the interfaces and interstitial sites of ferrite. On the other hand, the trapping sites of MoC were ferrite interstitial sites; the interface had a negative binding energy with H. Thermal desorption analysis confirms that the amounts of diffusible hydrogen were significantly reduced by addition of Mo in Ti-bearing steel.

  16. 75 FR 13320 - Florida Power Corporation, et al., Crystal River Unit 3 Nuclear Generating Plant; Environmental...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-19

    ... replacement outage that is currently underway at CR-3. In addition to steam generators, other large components (e.g., moisture separators and large heat exchangers) are being replaced during this outage... on the Internet at the NRC Web site: http://www.nrc.gov/reading-rm/adams.html . Persons who do not...

  17. 78 FR 2398 - Motorola Mobility LLC and Google Inc.; Analysis of Proposed Consent Order to Aid Public Comment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ... responsible for making sure that your comment does not include any sensitive health information, like medical records or other individually identifiable health information. In addition, do not include any ``[t]rade... overnight service. Visit the Commission Web site at http://www.ftc.gov to read this Notice and the news...

  18. 31 CFR 546.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[DARFUR].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found...

  19. 31 CFR 551.201 - Prohibited transactions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[SOMALIA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found...

  20. 31 CFR 552.201 - Prohibited transactions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[YEMEN].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in...

  1. 31 CFR 552.201 - Prohibited transactions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[YEMEN].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in...

  2. 31 CFR 548.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[BELARUS].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be...

  3. 31 CFR 593.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[LIBERIA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix...

  4. 31 CFR 548.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[BELARUS].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be...

  5. 31 CFR 593.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[LIBERIA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix...

  6. 31 CFR 546.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[DARFUR].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found...

  7. 31 CFR 593.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[LIBERIA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix...

  8. 31 CFR 593.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[LIBERIA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix...

  9. 31 CFR 551.201 - Prohibited transactions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[SOMALIA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found...

  10. 31 CFR 551.201 - Prohibited transactions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[SOMALIA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found...

  11. 31 CFR 546.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[DARFUR].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found...

  12. 31 CFR 548.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[BELARUS].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be...

  13. 31 CFR 551.201 - Prohibited transactions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[SOMALIA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found...

  14. 31 CFR 546.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[DARFUR].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found...

  15. 77 FR 2777 - Unblocking of One Specially Designated National or Blocked Person Pursuant to Executive Order...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ...,'' as amended by Executive Order 13350 of July 30, 2004. DATES: The removal of this entity from the SDN... The SDN List and additional information concerning OFAC are available from OFAC's web site ( www... property were blocked pursuant to Executive Order 13315, as amended, should be removed from the SDN List...

  16. 31 CFR 548.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Foreign Assets Control's Specially Designated Nationals and Blocked Persons List (“SDN List”) with the identifier “[BELARUS].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be...

  17. Estimating interaction on an additive scale between continuous determinants in a logistic regression model.

    PubMed

    Knol, Mirjam J; van der Tweel, Ingeborg; Grobbee, Diederick E; Numans, Mattijs E; Geerlings, Mirjam I

    2007-10-01

    To determine the presence of interaction in epidemiologic research, typically a product term is added to the regression model. In linear regression, the regression coefficient of the product term reflects interaction as departure from additivity. However, in logistic regression it refers to interaction as departure from multiplicativity. Rothman has argued that interaction estimated as departure from additivity better reflects biologic interaction. So far, literature on estimating interaction on an additive scale using logistic regression only focused on dichotomous determinants. The objective of the present study was to provide the methods to estimate interaction between continuous determinants and to illustrate these methods with a clinical example. and results From the existing literature we derived the formulas to quantify interaction as departure from additivity between one continuous and one dichotomous determinant and between two continuous determinants using logistic regression. Bootstrapping was used to calculate the corresponding confidence intervals. To illustrate the theory with an empirical example, data from the Utrecht Health Project were used, with age and body mass index as risk factors for elevated diastolic blood pressure. The methods and formulas presented in this article are intended to assist epidemiologists to calculate interaction on an additive scale between two variables on a certain outcome. The proposed methods are included in a spreadsheet which is freely available at: http://www.juliuscenter.nl/additive-interaction.xls.

  18. What Motivates Young Adults to Talk About Physical Activity on Social Network Sites?

    PubMed

    Zhang, Ni; Campo, Shelly; Yang, Jingzhen; Eckler, Petya; Snetselaar, Linda; Janz, Kathleen; Leary, Emily

    2017-06-22

    Electronic word-of-mouth on social network sites has been used successfully in marketing. In social marketing, electronic word-of-mouth about products as health behaviors has the potential to be more effective and reach more young adults than health education through traditional mass media. However, little is known about what motivates people to actively initiate electronic word-of-mouth about health behaviors on their personal pages or profiles on social network sites, thus potentially reaching all their contacts on those sites. This study filled the gap by applying a marketing theoretical model to explore the factors associated with electronic word-of-mouth on social network sites about leisure-time physical activity. A Web survey link was sent to undergraduate students at one of the Midwestern universities and 439 of them completed the survey. The average age of the 439 participants was 19 years (SD=1 year, range: 18-24). Results suggested that emotional engagement with leisure-time physical activity (ie, affective involvement in leisure-time physical activity) predicted providing relevant opinions or information on social network sites. Social network site users who perceived stronger ties with all their contacts were more likely to provide and seek leisure-time physical activity opinions and information. People who provided leisure-time physical activity opinions and information were more likely to seek opinions and information, and people who forwarded information about leisure-time physical activity were more likely to chat about it. This study shed light on the application of the electronic word-of-mouth theoretical framework in promoting health behaviors. The findings can also guide the development of future social marketing interventions using social network sites to promote leisure-time physical activity. ©Ni Zhang, Shelly Campo, Jingzhen Yang, Petya Eckler, Linda Snetselaar, Kathleen Janz, Emily Leary. Originally published in the Journal of Medical

  19. Real-Time Detection of Infusion Site Failures in a Closed-Loop Artificial Pancreas.

    PubMed

    Howsmon, Daniel P; Baysal, Nihat; Buckingham, Bruce A; Forlenza, Gregory P; Ly, Trang T; Maahs, David M; Marcal, Tatiana; Towers, Lindsey; Mauritzen, Eric; Deshpande, Sunil; Huyett, Lauren M; Pinsker, Jordan E; Gondhalekar, Ravi; Doyle, Francis J; Dassau, Eyal; Hahn, Juergen; Bequette, B Wayne

    2018-05-01

    As evidence emerges that artificial pancreas systems improve clinical outcomes for patients with type 1 diabetes, the burden of this disease will hopefully begin to be alleviated for many patients and caregivers. However, reliance on automated insulin delivery potentially means patients will be slower to act when devices stop functioning appropriately. One such scenario involves an insulin infusion site failure, where the insulin that is recorded as delivered fails to affect the patient's glucose as expected. Alerting patients to these events in real time would potentially reduce hyperglycemia and ketosis associated with infusion site failures. An infusion site failure detection algorithm was deployed in a randomized crossover study with artificial pancreas and sensor-augmented pump arms in an outpatient setting. Each arm lasted two weeks. Nineteen participants wore infusion sets for up to 7 days. Clinicians contacted patients to confirm infusion site failures detected by the algorithm and instructed on set replacement if failure was confirmed. In real time and under zone model predictive control, the infusion site failure detection algorithm achieved a sensitivity of 88.0% (n = 25) while issuing only 0.22 false positives per day, compared with a sensitivity of 73.3% (n = 15) and 0.27 false positives per day in the SAP arm (as indicated by retrospective analysis). No association between intervention strategy and duration of infusion sets was observed ( P = .58). As patient burden is reduced by each generation of advanced diabetes technology, fault detection algorithms will help ensure that patients are alerted when they need to manually intervene. Clinical Trial Identifier: www.clinicaltrials.gov,NCT02773875.

  20. 75 FR 33949 - Mandatory Reporting of Greenhouse Gases

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    .... The http://www.regulations.gov Web site is an ``anonymous access'' system, which means EPA will not.../emissions/ghgrulemaking.html . Alternatively, contact Carole Cook at 202-343-9263. Worldwide Web (WWW). In... greenhouse gas reporting rule Web site at http://www.epa.gov/climatechange/emissions/ghgrulemaking.html...

  1. Modeling of Substitutional Site Preference in Ordered Intermetallic Alloys

    NASA Technical Reports Server (NTRS)

    Bozzolo, Guillermo; Noebe, Ronald D.; Honecy, Frank

    1998-01-01

    We investigate the site substitution scheme of specific alloying elements in ordered compounds and the dependence of site occupancy on compound stoichiometry, alloy concentration. This basic knowledge, and the interactions with other alloying additions are necessary in order to predict and understand the effect of various alloying schemes on the physical properties of a material, its response to various temperature treatments, and the resulting mechanical properties. Many theoretical methods can provide useful but limited insight in this area, since most techniques suffer from constraints in the type of elements and the crystallographic structures that can be modeled. With this in mind, the Bozzolo-Ferrante-Smith (BFS) method for alloys was designed to overcome these limitations, with the intent of providing an useful tool for the theoretical prediction of fundamental properties and structure of complex systems. After a brief description of the BFS method, its use for the determination of site substitution schemes for individual as well as collective alloying additions to intermetallic systems is described, including results for the concentration dependence of the lattice parameter. Focusing on B2 NiAl, FeAl and CoAl alloys, the energetics of Si, Ti, V, Cr, Fe, Co, Ni, Cu, Zr, Nb, Mo, Ru, Hf, Ta and W alloying additions are surveyed. The effect of single additions as well as the result of two simultaneous additions, discussing the interaction between additions and their influence on site preference schemes is considered. Finally, the BFS analysis is extended to ternary L1(sub 2) (Heusler phase) alloys. A comparison between experimental and theoretical results for the limited number of cases for which experimental data is available is also included.

  2. Publishing on the WWW. Part 1 - Static graphics

    PubMed Central

    Grech, V

    2000-01-01

    An on-line journal's ability to publish graphics at no additional cost is a major advantage over conventional printed journals. This article outlines technical, copyright and other issues related to graphic publishing on the world-wide-web. PMID:22368588

  3. JET2 Viewer: a database of predicted multiple, possibly overlapping, protein-protein interaction sites for PDB structures.

    PubMed

    Ripoche, Hugues; Laine, Elodie; Ceres, Nicoletta; Carbone, Alessandra

    2017-01-04

    The database JET2 Viewer, openly accessible at http://www.jet2viewer.upmc.fr/, reports putative protein binding sites for all three-dimensional (3D) structures available in the Protein Data Bank (PDB). This knowledge base was generated by applying the computational method JET 2 at large-scale on more than 20 000 chains. JET 2 strategy yields very precise predictions of interacting surfaces and unravels their evolutionary process and complexity. JET2 Viewer provides an online intelligent display, including interactive 3D visualization of the binding sites mapped onto PDB structures and suitable files recording JET 2 analyses. Predictions were evaluated on more than 15 000 experimentally characterized protein interfaces. This is, to our knowledge, the largest evaluation of a protein binding site prediction method. The overall performance of JET 2 on all interfaces are: Sen = 52.52, PPV = 51.24, Spe = 80.05, Acc = 75.89. The data can be used to foster new strategies for protein-protein interactions modulation and interaction surface redesign. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  4. Site safety plan for Lawrence Livermore National Laboratory CERCLA investigations at site 300. Revision 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kilmer, J.

    Various Department of Energy Orders incorporate by reference, health and safety regulations promulgated by the Occupational Safety and Health Administration (OSHA). One of the OSHA regulations, 29 CFR 1910.120, Hazardous Waste Operations and Emergency Response, requires that site safety plans are written for activities such as those covered by work plans for Site 300 environmental investigations. Based upon available data, this Site Safety Plan (Plan) for environmental restoration has been prepared specifically for the Lawrence Livermore National Laboratory Site 300, located approximately 15 miles east of Livermore, California. As additional facts, monitoring data, or analytical data on hazards are provided,more » this Plan may need to be modified. It is the responsibility of the Environmental Restoration Program and Division (ERD) Site Safety Officer (SSO), with the assistance of Hazards Control, to evaluate data which may impact health and safety during these activities and to modify the Plan as appropriate. This Plan is not `cast-in-concrete.` The SSO shall have the authority, with the concurrence of Hazards Control, to institute any change to maintain health and safety protection for workers at Site 300.« less

  5. Parametric Studies for Scenario Earthquakes: Site Effects and Differential Motion

    NASA Astrophysics Data System (ADS)

    Panza, G. F.; Panza, G. F.; Romanelli, F.

    2001-12-01

    In presence of strong lateral heterogeneities, the generation of local surface waves and local resonance can give rise to a complicated pattern in the spatial groundshaking scenario. For any object of the built environment with dimensions greater than the characteristic length of the ground motion, different parts of its foundations can experience severe non-synchronous seismic input. In order to perform an accurate estimate of the site effects, and of differential motion, in realistic geometries, it is necessary to make a parametric study that takes into account the complex combination of the source and propagation parameters. The computation of a wide set of time histories and spectral information, corresponding to possible seismotectonic scenarios for different source and structural models, allows us the construction of damage scenarios that are out of reach of stochastic models. Synthetic signals, to be used as seismic input in a subsequent engineering analysis, e.g. for the design of earthquake-resistant structures or for the estimation of differential motion, can be produced at a very low cost/benefit ratio. We illustrate the work done in the framework of a large international cooperation following the guidelines of the UNESCO IUGS IGCP Project 414 "Realistic Modeling of Seismic Input for Megacities and Large Urban Areas" and show the very recent numerical experiments carried out within the EC project "Advanced methods for assessing the seismic vulnerability of existing motorway bridges" (VAB) to assess the importance of non-synchronous seismic excitation of long structures. >http://www.ictp.trieste.it/www_users/sand/projects.html

  6. 76 FR 80377 - Notice of Submission of Proposed Information Collection to OMB Additional On-Site Data Collection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... with PHA staff and reviews of client files and administrative data collected by the PHA. The results of... reviews of client files and administrative data collected by the PHA. The results of the site visits will...

  7. Multiple grid arrangement improves ligand docking with unknown binding sites: Application to the inverse docking problem.

    PubMed

    Ban, Tomohiro; Ohue, Masahito; Akiyama, Yutaka

    2018-04-01

    The identification of comprehensive drug-target interactions is important in drug discovery. Although numerous computational methods have been developed over the years, a gold standard technique has not been established. Computational ligand docking and structure-based drug design allow researchers to predict the binding affinity between a compound and a target protein, and thus, they are often used to virtually screen compound libraries. In addition, docking techniques have also been applied to the virtual screening of target proteins (inverse docking) to predict target proteins of a drug candidate. Nevertheless, a more accurate docking method is currently required. In this study, we proposed a method in which a predicted ligand-binding site is covered by multiple grids, termed multiple grid arrangement. Notably, multiple grid arrangement facilitates the conformational search for a grid-based ligand docking software and can be applied to the state-of-the-art commercial docking software Glide (Schrödinger, LLC). We validated the proposed method by re-docking with the Astex diverse benchmark dataset and blind binding site situations, which improved the correct prediction rate of the top scoring docking pose from 27.1% to 34.1%; however, only a slight improvement in target prediction accuracy was observed with inverse docking scenarios. These findings highlight the limitations and challenges of current scoring functions and the need for more accurate docking methods. The proposed multiple grid arrangement method was implemented in Glide by modifying a cross-docking script for Glide, xglide.py. The script of our method is freely available online at http://www.bi.cs.titech.ac.jp/mga_glide/. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

  8. Development of a QTL-environment-based predictive model for node addition rate in common bean.

    PubMed

    Zhang, Li; Gezan, Salvador A; Eduardo Vallejos, C; Jones, James W; Boote, Kenneth J; Clavijo-Michelangeli, Jose A; Bhakta, Mehul; Osorno, Juan M; Rao, Idupulapati; Beebe, Stephen; Roman-Paoli, Elvin; Gonzalez, Abiezer; Beaver, James; Ricaurte, Jaumer; Colbert, Raphael; Correll, Melanie J

    2017-05-01

    This work reports the effects of the genetic makeup, the environment and the genotype by environment interactions for node addition rate in an RIL population of common bean. This information was used to build a predictive model for node addition rate. To select a plant genotype that will thrive in targeted environments it is critical to understand the genotype by environment interaction (GEI). In this study, multi-environment QTL analysis was used to characterize node addition rate (NAR, node day - 1 ) on the main stem of the common bean (Phaseolus vulgaris L). This analysis was carried out with field data of 171 recombinant inbred lines that were grown at five sites (Florida, Puerto Rico, 2 sites in Colombia, and North Dakota). Four QTLs (Nar1, Nar2, Nar3 and Nar4) were identified, one of which had significant QTL by environment interactions (QEI), that is, Nar2 with temperature. Temperature was identified as the main environmental factor affecting NAR while day length and solar radiation played a minor role. Integration of sites as covariates into a QTL mixed site-effect model, and further replacing the site component with explanatory environmental covariates (i.e., temperature, day length and solar radiation) yielded a model that explained 73% of the phenotypic variation for NAR with root mean square error of 16.25% of the mean. The QTL consistency and stability was examined through a tenfold cross validation with different sets of genotypes and these four QTLs were always detected with 50-90% probability. The final model was evaluated using leave-one-site-out method to assess the influence of site on node addition rate. These analyses provided a quantitative measure of the effects on NAR of common beans exerted by the genetic makeup, the environment and their interactions.

  9. The Savannah River Site`s groundwater monitoring program. Third quarter 1990

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1991-05-06

    The Environmental Protection Department/Environmental Monitoring Section (EPD/EMS) administers the Savannah River Site`s (SRS) Groundwater Monitoring Program. During third quarter 1990 (July through September) EPD/EMS conducted routine sampling of monitoring wells and drinking water locations. EPD/EMS established two sets of flagging criteria in 1986 to assist in the management of sample results. The flagging criteria do not define contamination levels; instead they aid personnel in sample scheduling, interpretation of data, and trend identification. The flagging criteria are based on detection limits, background levels in SRS groundwater, and drinking water standards. All analytical results from third quarter 1990 are listed in thismore » report, which is distributed to all site custodians. One or more analytes exceeded Flag 2 in 87 monitoring well series. Analytes exceeded Flat 2 for the first since 1984 in 14 monitoring well series. In addition to groundwater monitoring, EPD/EMS collected drinking water samples from SRS drinking water systems supplied by wells. The drinking water samples were analyzed for radioactive constituents.« less

  10. Perioperative oxygen supplementation and surgical site infection after cesarean delivery: a randomized trial.

    PubMed

    Duggal, Neena; Poddatoori, Vineela; Poddatorri, Vineela; Noroozkhani, Sara; Siddik-Ahmad, R Iram; Caughey, Aaron B

    2013-07-01

    To evaluate whether supplemental perioperative oxygen decreases surgical site wound infections or endometritis. This was a prospective, randomized trial. Patients who were to undergo cesarean delivery were recruited and randomly allocated to either 30% or 80% oxygen during the cesarean delivery and for 1 hour after surgery. The obstetricians and patients were blinded to the concentration of oxygen used. Patients were evaluated for wound infection or endometritis during their hospital stay and by 6 weeks postpartum. The primary end point was a composite of either surgical site infection or endometritis. Eight hundred thirty-one patients were recruited. Of these, 415 participants received 30% oxygen perioperatively and 416 received 80% oxygen. The groups were well matched for age, race, parity, diabetes, number of previous cesarean deliveries, and scheduled compared with unscheduled cesarean deliveries. An intention-to-treat analysis was used. There was no difference in the primary composite outcome (8.2% in women who received 30% oxygen compared with 8.2% in women who received 80% oxygen, P=.89), no difference in surgical site infection in the two groups (5.5% compared with 5.8%, P=.98), and no significant difference in endometritis in the two groups (2.7% compared with 2.4%, P=.66), respectively. Women who received 80% supplemental oxygen perioperatively did not have a lower rate of a surgical site infection or endometritis as compared with women who received 30% supplemental oxygen concentration. ClinicalTrials.gov, www.clincaltrials.gov, NCT00876005. I.

  11. Accessibility of School Districts' Web Sites: A Descriptive Study

    ERIC Educational Resources Information Center

    Bray, Marty; Flowers, Claudia; Gibson, Patricia

    2003-01-01

    Many school districts (SDs) use the World Wide Web (WWW or Web) to disseminate a wide variety of information about things such as district events, policies, and a wide variety of student information. On-line barriers limit the accessibility of the WWW for persons and students with disabilities and thus can limit their access to vital information.…

  12. 31 CFR 576.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Blocked Persons List (“SDN List”) with the identifier “[IRAQ2]” (for persons designated pursuant to...)(3) of this section). The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List...

  13. 31 CFR 576.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Blocked Persons List (“SDN List”) with the identifier “[IRAQ2]” (for persons designated pursuant to...)(3) of this section). The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List...

  14. 31 CFR 576.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Blocked Persons List (“SDN List”) with the identifier “[IRAQ2]” (for persons designated pursuant to...)(3) of this section). The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List...

  15. 31 CFR 576.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Blocked Persons List (“SDN List”) with the identifier “[IRAQ2]” (for persons designated pursuant to...)(3) of this section). The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List...

  16. 76 FR 46350 - Agency Self-Evaluation Under Section 504 of the Rehabilitation Act of 1973; Public Forums on...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-02

    ... communications. In addition, we will record and stream each public forum live on the Internet. Accordingly, each... the recording will be streamed live on the internet during the event and available thereafter for...-772-1213 or TTY 1-800-325- 0778, or visit our Internet site, Social Security Online at http://www...

  17. 77 FR 26316 - Progress Energy Florida; Final Environmental Impact Statement for Combined Licenses for Levy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-03

    ..., Rockville, Maryland, 20852 or from NRC's Agencywide Documents Access and Management System (ADAMS). ADAMS is accessible from the NRC's Web site at www.nrc.gov/reading-rm/adams.html . The ADAMS accession numbers for the... . In addition, the following four public libraries have agreed to make the final EIS available to the...

  18. 10 CFR 2.704 - Discovery-required disclosures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... at the NRC Web site, http://www.nrc.gov, and/or the NRC Public Document Room, a sufficient disclosure... based on the information then reasonably available to it. A party is not excused from making its... disclosures when required under paragraph (e) of this section. (c) Pretrial disclosures. (1) In addition to...

  19. Skin Preparation for Prevention of Surgical Site Infection After Cesarean Delivery: A Randomized Controlled Trial.

    PubMed

    Ngai, Ivan M; Van Arsdale, Anne; Govindappagari, Shravya; Judge, Nancy E; Neto, Nicole K; Bernstein, Jeffrey; Bernstein, Peter S; Garry, David J

    2015-12-01

    To compare chlorhexidine with alcohol, povidone-iodine with alcohol, and both applied sequentially to estimate their relative effectiveness in prevention of surgical site infections after cesarean delivery. Women undergoing nonemergent cesarean birth at greater than 37 0/7 weeks of gestation were randomly allocated to one of three antiseptic skin preparations: povidone-iodine with alcohol, chlorhexidine with alcohol, or the sequential combination of both solutions. The primary outcome was surgical site infection reported within the first 30 days postpartum. Based on a surgical site infection rate of 12%, an anticipated 50% reduction for the combination group relative to either single skin preparation group, with a power of 0.90 and an α of 0.05, 430 women per group were needed to detect a difference. From January 2013 to July 2014, 1,404 women were randomly assigned to one of three groups: povidone-iodine with alcohol (n=463), chlorhexidine with alcohol (n=474), or both (n=467). The groups were similar with respect to demographics, medical disorders, indication for cesarean delivery, operative time, and blood loss. The overall rate of surgical site infection-4.3%-was lower than anticipated. The skin preparation groups had similar surgical site infection rates: povidone-iodine 4.6%, chlorhexidine with alcohol 4.5%, and sequential 3.9% (P=.85). The skin preparation techniques resulted in similar rates of surgical site infections. Our study provides no support for any particular method of skin preparation before cesarean delivery. ClinicalTrials.gov, www.clinicaltrials.gov, NCT01870583. I.

  20. NASA GSFC Tin Whisker Homepage http://nepp.nasa.gov/whisker

    NASA Technical Reports Server (NTRS)

    Shaw, Harry

    2000-01-01

    The NASA GSFC Tin Whisker Homepage provides general information and GSFC Code 562 experimentation results regarding the well known phenomenon of tin whisker formation from pure tin plated substrates. The objective of this www site is to provide a central repository for information pertaining to this phenomenon and to provide status of the GSFC experiments to understand the behavior of tin whiskers in space environments. The Tin Whisker www site is produced by Code 562. This www site does not provide information pertaining to patented or proprietary information. All of the information contained in this www site is at the level of that produced by industry and university researchers and is published at international conferences.

  1. Genetics on the World Wide Web.

    PubMed

    Trangenstein, P A; Hetteberg, C

    1998-11-01

    Since 1990, when the Human Genome Project was initiated, the amount of genetic information on the World Wide Web (WWW) has grown substantially. The WWW has become an important resource for current, accurate, and reliable genetic information for health care professionals and the general public. The purpose of this article is to provide a variety of genetics-related WWW sites that are useful for all levels of practitioners interested in genetics. In selecting sites to be included in this article, a number of evaluation tools were reviewed. The primary concern was that these sites be reputable and provide accurate, timely information. A table of the WWW sites is included for quick easy reference.

  2. 75 FR 40864 - Notice of Fiscal Year 2010 Border Grant Funding and Solicitation for Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-14

    ... Federal Grant Web site, http://www.grants.gov . Eligible projects for funding with BEG are identified in... applications for BEG funding at the Federal Grant Web site, http://www.grants.gov . FOR FURTHER INFORMATION... the MOE explanation, http://www.fmcsa.dot.gov/safety-security/grants/beg/moe.aspx . The Border...

  3. Site 765: Sedimentology

    USGS Publications Warehouse

    ,

    1990-01-01

    Various techniques were used to decipher the sedimentation history of Site 765, including Markov chain analysis of facies transitions, XRD analysis of clay and other minerals, and multivariate analysis of smear-slide data, in addition to the standard descriptive procedures employed by the shipboard sedimentologist. This chapter presents brief summaries of methodology and major findings of these three techniques, a summary of the sedimentation history, and a discussion of trends in sedimentation through time.

  4. iSS-PC: Identifying Splicing Sites via Physical-Chemical Properties Using Deep Sparse Auto-Encoder.

    PubMed

    Xu, Zhao-Chun; Wang, Peng; Qiu, Wang-Ren; Xiao, Xuan

    2017-08-15

    Gene splicing is one of the most significant biological processes in eukaryotic gene expression, such as RNA splicing, which can cause a pre-mRNA to produce one or more mature messenger RNAs containing the coded information with multiple biological functions. Thus, identifying splicing sites in DNA/RNA sequences is significant for both the bio-medical research and the discovery of new drugs. However, it is expensive and time consuming based only on experimental technique, so new computational methods are needed. To identify the splice donor sites and splice acceptor sites accurately and quickly, a deep sparse auto-encoder model with two hidden layers, called iSS-PC, was constructed based on minimum error law, in which we incorporated twelve physical-chemical properties of the dinucleotides within DNA into PseDNC to formulate given sequence samples via a battery of cross-covariance and auto-covariance transformations. In this paper, five-fold cross-validation test results based on the same benchmark data-sets indicated that the new predictor remarkably outperformed the existing prediction methods in this field. Furthermore, it is expected that many other related problems can be also studied by this approach. To implement classification accurately and quickly, an easy-to-use web-server for identifying slicing sites has been established for free access at: http://www.jci-bioinfo.cn/iSS-PC.

  5. 76 FR 800 - Policy and Procedural Change Regarding the Publication of Notices of Funding Opportunities in the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-06

    ... Web site, http://www.grants.gov , in accordance with the policy directive issued by the Office of... posted at http://www.grants.gov by following the universal resource locator (URL) link included in the synopsis, or by visiting ETA's Web site at http://www.doleta.gov . DATES: Effective Date: January 6, 2011...

  6. 78 FR 60271 - Hollow Dam Power Company; Ampersand Hollow Dam Hydro, LLC; Notice of Application for Transfer of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-01

    ...Library link of Commission's Web site at http://www.ferc.gov/docs-filing/elibrary.asp . Enter the docket...) and the instructions on the Commission's Web site under http://www.ferc.gov/docs-filing/efiling.asp... system at http://www.ferc.gov/docs-filing/ecomment.asp . You must include your name and contact...

  7. 78 FR 38027 - Wilkesboro Hydroelectric Company, LLC; Wilkesboro Hydropower, LLC; Notice of Application for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-25

    ... viewed or printed on the eLibrary link of Commission's Web site at http://www.ferc.gov/docs-filing... Commission's Web site under http://www.ferc.gov/docs-filing/efiling.asp . Commenters can submit brief comments up to 6,000 characters, without prior registration, using the eComment system at http://www.ferc...

  8. 78 FR 934 - 37 Wilton Road, Milford LLC, and 282 Route 101 LLC, PVM Commercial Center, LLC; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-07

    ... printed on the eLibrary link of Commission's Web site at http://www.ferc.gov/docs-filing/elibrary.asp... Commission's Web site under http://www.ferc.gov/docs-filing/efiling.asp . Commenters can submit brief comments up to 6,000 characters, without prior registration, using the eComment system at http://www.ferc...

  9. The WORM site: worm.csirc.net

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jones, T.

    2000-07-01

    The Write One, Run Many (WORM) site (worm.csirc.net) is the on-line home of the WORM language and is hosted by the Criticality Safety Information Resource Center (CSIRC) (www.csirc.net). The purpose of this web site is to create an on-line community for WORM users to gather, share, and archive WORM-related information. WORM is an embedded, functional, programming language designed to facilitate the creation of input decks for computer codes that take standard ASCII text files as input. A functional programming language is one that emphasizes the evaluation of expressions, rather than execution of commands. The simplest and perhaps most common examplemore » of a functional language is a spreadsheet such as Microsoft Excel. The spreadsheet user specifies expressions to be evaluated, while the spreadsheet itself determines the commands to execute, as well as the order of execution/evaluation. WORM functions in a similar fashion and, as a result, is very simple to use and easy to learn. WORM improves the efficiency of today's criticality safety analyst by allowing: (1) input decks for parameter studies to be created quickly and easily; (2) calculations and variables to be embedded into any input deck, thus allowing for meaningful parameter specifications; (3) problems to be specified using any combination of units; and (4) complex mathematically defined models to be created. WORM is completely written in Perl. Running on all variants of UNIX, Windows, MS-DOS, MacOS, and many other operating systems, Perl is one of the most portable programming languages available. As such, WORM works on practically any computer platform.« less

  10. Viking site selection and certification

    NASA Technical Reports Server (NTRS)

    Masursky, H.; Crabill, N. L.

    1981-01-01

    The landing site selection and certification effort for the Viking mission to Mars is reviewed from the premission phase through the acquisition of data and decisions during mission operations and the immediate postlanding evaluation. The utility and limitations of the orbital television and infrared data and ground based radar observation of candidate and actual landing sites are evaluated. Additional instruments and types of observations which would have been useful include higher resolution cameras, radar altimeters, and terrain hazard avoidance capability in the landing system. Suggestions based on this experience that might be applied to future missions are included.

  11. Analysis of ILRS Site Ties

    NASA Astrophysics Data System (ADS)

    Husson, V. S.; Long, J. L.; Pearlman, M.

    2001-12-01

    By the end of 2000, 94% of ILRS stations had completed station and site information forms (i.e. site logs). These forms contain six types of information. These six categories include site identifiers, contact information, approximate coordinates, system configuration history, system ranging capabilities, and local survey ties. The ILRS Central Bureau, in conjunction with the ILRS Networks and Engineering Working Group, has developed procedures to quality control site log contents. Part of this verification entails data integrity checks of local site ties and is the primary focus of this paper. Local survey ties are critical to the combination of space geodetic network coordinate solutions (i.e. GPS, SLR, VLBI, DORIS) of the International Terrestrial Reference Frame (ITRF). Approximately 90% of active SLR sites are collocated with at least one other space geodetic technique. The process used to verify these SLR ties, at collocated sites, is identical to the approach used in ITRF2000. Local vectors (X, Y, Z) from each ILRS site log are differenced from its corresponding ITRF2000 position vectors (i.e. no transformations). These X, Y, and Z deltas are converted into North, East, and Up. Any deltas, in any component, larger than 5 millimeter is flagged for investigation. In the absence of ITRF2000 SLR positions, CSR positions were used. To further enhance this comparison and to fill gaps in information, local ties contained in site logs from the other space geodetic services (i.e. IGS, IVS, IDS) were used in addition to ITRF2000 ties. Case studies of two collocated sites (McDonald/Ft. Davis and Hartebeeshtoek) will be explored in-depth. Recommendations on how local site surveys should be conducted and how this information should be managed will also be presented.

  12. PolyA_DB 3 catalogs cleavage and polyadenylation sites identified by deep sequencing in multiple genomes

    PubMed Central

    Wang, Ruijia; Nambiar, Ram; Zheng, Dinghai

    2018-01-01

    Abstract PolyA_DB is a database cataloging cleavage and polyadenylation sites (PASs) in several genomes. Previous versions were based mainly on expressed sequence tags (ESTs), which had a limited amount and could lead to inaccurate PAS identification due to the presence of internal A-rich sequences in transcripts. Here, we present an updated version of the database based solely on deep sequencing data. First, PASs are mapped by the 3′ region extraction and deep sequencing (3′READS) method, ensuring unequivocal PAS identification. Second, a large volume of data based on diverse biological samples increases PAS coverage by 3.5-fold over the EST-based version and provides PAS usage information. Third, strand-specific RNA-seq data are used to extend annotated 3′ ends of genes to obtain more thorough annotations of alternative polyadenylation (APA) sites. Fourth, conservation information of PAS across mammals sheds light on significance of APA sites. The database (URL: http://www.polya-db.org/v3) currently holds PASs in human, mouse, rat and chicken, and has links to the UCSC genome browser for further visualization and for integration with other genomic data. PMID:29069441

  13. R4FRS_RCRAINFO

    EPA Pesticide Factsheets

    To improve public health and the environment, the United States Environmental Protection Agency (USEPA) collects information about facilities, sites, or places subject to environmental regulation or of environmental interest. Through the Geospatial Data Download Service, the public is now able to download the EPA Geodata shapefile containing facility and site information from EPA's national program systems. The file is Internet accessible from the Envirofacts Web site (http://www.epa.gov/enviro). The data may be used with geospatial mapping applications. (Note: The shapefile omits facilities without latitude/longitude coordinates.) The EPA Geospatial Data contains the name, location (latitude/longitude), and EPA program information about specific facilities and sites. In addition, the file contains a Uniform Resource Locator (URL), which allows mapping applications to present an option to users to access additional EPA data resources on a specific facility or site.

  14. US EPA Region 4 RMP Facilities

    EPA Pesticide Factsheets

    To improve public health and the environment, the United States Environmental Protection Agency (USEPA) collects information about facilities, sites, or places subject to environmental regulation or of environmental interest. Through the Geospatial Data Download Service, the public is now able to download the EPA Geodata shapefile containing facility and site information from EPA's national program systems. The file is Internet accessible from the Envirofacts Web site (http://www.epa.gov/enviro). The data may be used with geospatial mapping applications. (Note: The shapefile omits facilities without latitude/longitude coordinates.) The EPA Geospatial Data contains the name, location (latitude/longitude), and EPA program information about specific facilities and sites. In addition, the file contains a Uniform Resource Locator (URL), which allows mapping applications to present an option to users to access additional EPA data resources on a specific facility or site.

  15. CHARACTERIZING SITE HYDROLOGY (WORKSHOP MSA PRESENTATION)

    EPA Science Inventory

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  16. CHARACTERIZING SITE HYDROLOGY (REGION 8 WORKSHOP)

    EPA Science Inventory

    Hydrogeology is the foundation of subsurface site characterization for evaluations of monitored natural attenuation (MNA). Three case studies are presented. Examples of the potentially detrimental effects of drilling additives on ground-water samples from monitoring wells are d...

  17. 31 CFR 588.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... List (“SDN List”) with the identifier “[BALKANS].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. See § 588.411 concerning...

  18. 31 CFR 549.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... List (“SDN List”) with the identifier “[LEBANON].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. See § 549.411 concerning...

  19. 31 CFR 549.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... List (“SDN List”) with the identifier “[LEBANON].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. See § 549.411 concerning...

  20. 31 CFR 536.312 - Specially designated narcotics trafficker.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... List (“SDN List”) with the identifier “[SDNT].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. Sections 501.806 and 501...

  1. 31 CFR 549.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... List (“SDN List”) with the identifier “[LEBANON].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. See § 549.411 concerning...

  2. 31 CFR 536.312 - Specially designated narcotics trafficker.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... List (“SDN List”) with the identifier “[SDNT].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. Sections 501.806 and 501...

  3. 31 CFR 542.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Persons List (“SDN List”) with the identifier “[SYRIA].” The names of persons listed in or designated... incorporated into the SDN List with the identifier “[HRIT-SY].” The SDN List is accessible through the following page on OFAC's Web site: www.treasury.gov/sdn. Additional information pertaining to the SDN List...

  4. 31 CFR 558.201 - Prohibited transactions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Designated Nationals and Blocked Persons List (SDN List) with the identifier “[SOUTH SUDAN].” The SDN List is accessible through the following page on OFAC's Web site: www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in Appendix A to this chapter. See § 558.406 concerning entities that...

  5. 31 CFR 536.312 - Specially designated narcotics trafficker.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... List (“SDN List”) with the identifier “[SDNT].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. Sections 501.806 and 501...

  6. 31 CFR 588.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... List (“SDN List”) with the identifier “[BALKANS].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. See § 588.411 concerning...

  7. 31 CFR 588.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... List (“SDN List”) with the identifier “[BALKANS].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. See § 588.411 concerning...

  8. 31 CFR 588.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... List (“SDN List”) with the identifier “[BALKANS].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. See § 588.411 concerning...

  9. 31 CFR 536.312 - Specially designated narcotics trafficker.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... List (“SDN List”) with the identifier “[SDNT].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. Sections 501.806 and 501...

  10. 31 CFR 549.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... List (“SDN List”) with the identifier “[LEBANON].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. See § 549.411 concerning...

  11. 78 FR 41891 - Proposed Establishment of the Upper Hiwassee Highlands Viticultural Area

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ... allow vintners to better describe the origin of their wines and to allow consumers to better identify wines they may purchase. TTB invites comments on this proposed addition to its regulations. DATES... Docket No. TTB-2013-0008. A link to that docket is posted on the TTB Web site at http://www.ttb.gov/wine...

  12. 76 FR 30060 - Proposed Establishment of the Naches Heights Viticultural Area (2009R-107P)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-24

    ... areas to allow vintners to better describe the origin of their wines and to allow consumers to better identify wines they may purchase. TTB invites comments on this proposed addition to the Bureau's.... TTB-2011-0005. A direct link to this docket is posted on the TTB Web site at http://www.ttb.gov/wine...

  13. Ocean Drilling Program: Mirror Sites

    Science.gov Websites

    Publication services and products Drilling services and tools Online Janus database Search the ODP/TAMU web information, see www.iodp-usio.org. ODP | Search | Database | Drilling | Publications | Science | Cruise Info

  14. 78 FR 14528 - Mayo Hydropower, LLC, Avalon Hydropower, LLC; Notice of Application for Transfer of License, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-06

    ... this project can be viewed or printed on the eLibrary link of Commission's Web site at http://www.ferc...) and the instructions on the Commission's Web site under http://www.ferc.gov/docs-filing/efiling.asp... system at http://www.ferc.gov/docs-filing/ecomment.asp . You must include your name and contact...

  15. Use of Additives in Bioremediation of Contaminated Groundwater and Soil

    EPA Science Inventory

    This chapter reviews application of additives used in bioremediation of chlorinated solvents and fuels for groundwater and soil remediation. Soluble carbon substrates are applicable to most site conditions except aquifers with very high or very low groundwater flow. Slow-release ...

  16. Site-Based Management: Avoiding Disaster While Sharing Decision Making.

    ERIC Educational Resources Information Center

    Sorenson, Larry Dean

    This paper argues that many site-based management practices do not represent true empowerment and are not founded on a consensual framework of values, goals, and priorities developed by educational stakeholders. In addition, they often lack clearly stated operating principles. The paper distinguishes between site-based management (SBM) and…

  17. Differential phosphorylation patterns of P-glycoprotein reconstituted into a proteoliposome system: insight into additional unconventional phosphorylation sites.

    PubMed

    Lelong-Rebel, Isabelle H; Cardarelli, Carol O

    2005-01-01

    Membrane vesicles from the multidrug-resistant KB-V1 and KB-C1 cell lines overexpressing P-glycoprotein (Pgp), responsible for pleiotropic chemotherapeutic agents resistance, were solubilized with octyl-glucoside (OG-EX) and further fractionated on DEAE-sepharose column with increased concentrations of NaCl. The fraction containing Pgp (F3) was reconstituted into proteoliposomes (F3-PLP). Comparisons of the phosphorylation levels of Pgp achieved throughout the purification and reconstitution steps were addressed in this study. The [delta32 P] ATP-driven phosphorylation of Pgp was strongly increased in OG-EX, decreased in F3 and not detected in F3-PLP, when compared to Pgp phosphorylation in native plasma membrane vesicles. [delta32 P]ATP-phosphorylation of Pgp in F3-PLP could be restored by exogenously added PKC or by the catalytic sub-unit of PKA. The vanadate-induced hyperphosphorylation effect on Pgp by [delta32 P]ATP observed with plasma membrane vesicles was maintained in OG-EX, but was lost in F3 and did not enable labelling in F3-PLP. Enhancement of [delta32 P]-labelling of native Pgp via [delta32 P]ATP combined with GTP was maintained and also triggered phosphorylation of purified/reconstituted Pgp in F3-PLP as well. Altogether, our data suggest differential phosphorylation patterns of the transporter linked to environmental molecular composition (lipids, presence of detergent) and structure (unfolded versus embedded). In addition, restoration by GTP of Pgp phosphorylation by [delta32 P]ATP in the frame of F3-PLP suggests intra-molecular modulations and hints that other phosphorylation sites and processes, different from the classic ones involving PKC and/or PKA, may participate in the transporter's mechanism.

  18. 2015 Advanced Site Investigation and Monitoring Report Riverton, Wyoming, Processing Site September 2016

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Frazier, William; Campbell, Sam

    The U.S. Department of Energy conducted initial groundwater characterization of the Riverton, Wyoming, Processing Site in the 1990s. The characterization culminated in a Site Observational Work Plan in 1998 that recommended a natural flushing compliance strategy. Results of verification monitoring indicated that natural flushing was generally progressing as expected until June 2010, when significant increases in contaminant concentrations were measured in several monitoring wells downgradient of the site after the area flooded. In response to the unexpected results following the flood, an enhanced characterization of the surficial aquifer was conducted in 2012, which included installation of 103 boreholes along ninemore » transects with a Geoprobe, collection of 103 water samples and 65 soil samples, laboratory tests on the soil samples, and additional groundwater modeling. This advanced site investigation report summarizes additional investigation in 2015 through the use of backhoe trenching, sonic drilling, multilevel monitoring wells, direct-push drilling, and temporary well points to collect soil and groundwater samples. Additional surface water measurements were made included the installation of a stilling well and the measurement of stream elevation along the Wind River to approximate upgradient groundwater heads. Groundwater sampling included the addition of geochemical constituents and isotopes that have not been sampled in the past to better understand post-flood conditions and the possibility of additional or ongoing contaminant sources. This sampling was performed to (1) better define the contaminant plumes, (2) verify the occurrence of persistent secondary contaminant sources, (3) better understand the reason for the contaminant spikes after a 2010 flood, and (4) assess contaminant plume stagnation near the Little Wind River. This report provides data analyses and interpretations for the 2015 site investigation that addresses these issues and provides

  19. 39 CFR 3004.13 - Notice and publication of public information.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Web site at http://www.prc.gov. (b) Descriptions of the Commission's organization, its methods of... the Federal Register publication system, and are available on the Commission's Web site, http://www...

  20. 39 CFR 3004.13 - Notice and publication of public information.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Web site at http://www.prc.gov. (b) Descriptions of the Commission's organization, its methods of... the Federal Register publication system, and are available on the Commission's Web site, http://www...

  1. 39 CFR 3004.13 - Notice and publication of public information.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Web site at http://www.prc.gov. (b) Descriptions of the Commission's organization, its methods of... the Federal Register publication system, and are available on the Commission's Web site, http://www...

  2. 39 CFR 3004.13 - Notice and publication of public information.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Web site at http://www.prc.gov. (b) Descriptions of the Commission's organization, its methods of... the Federal Register publication system, and are available on the Commission's Web site, http://www...

  3. 39 CFR 3004.13 - Notice and publication of public information.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Web site at http://www.prc.gov. (b) Descriptions of the Commission's organization, its methods of... the Federal Register publication system, and are available on the Commission's Web site, http://www...

  4. 76 FR 70412 - Smart Grid Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-14

    ... recommendations that the Committee will consider at the meeting will be posted on the SGAC Web site at http://www... posted on the Smart Grid Web site at http://www.nist.gov/smartgrid . DATES: The SGAC will hold a meeting... (5 U.S.C. App.). Background information on the Committee is available at http://www.nist.gov...

  5. 78 FR 78349 - Andrew Peklo III; Notice of Availability of Draft Environmental Assessment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-26

    ... draft EA may also be viewed on the Commission's Web site at http://www.ferc.gov using the ``eLibrary... CFR 385.2001(a)(1)(iii) and the instructions on the Commission's Web site http://www.ferc.gov/docs... registration, using the eComment system at http://www.ferc.gov/docs-filing/ecomment.asp . You must include your...

  6. 76 FR 10054 - Notice of Availability: Notice of Technical Correction to the Notice of Funding Availability for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-23

    ...: Notice. SUMMARY: On January 20, 2011, HUD posted on http://www.Grants.gov , a Notice of Funding... Housing and Urban Development agency link on the Grants.gov/Find Web site at http://www.grants.gov/search/agency.do . A link to Grants.gov is also available on the HUD Web site at http://www.hud.gov/offices/adm...

  7. 29 CFR 1917.3 - Incorporation by reference.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...: 212-642-4900; fax: 212-398-0023; Web site: http://www.ansi.org. (1) ANSI A14.1-1990, Safety..., Itasca, IL 60143-0558; telephone: 1-800-621-7619; fax: 708-285-0797; Web site: http://www.nsc.org. (5...://www.nsc.org. (6) ANSI Z87.1-2003, American National Standard Practice for Occupational and Educational...

  8. Endogenous Hot Spots of De Novo Telomere Addition in the Yeast Genome Contain Proximal Enhancers That Bind Cdc13

    PubMed Central

    Obodo, Udochukwu C.; Epum, Esther A.; Platts, Margaret H.; Seloff, Jacob; Dahlson, Nicole A.; Velkovsky, Stoycho M.; Paul, Shira R.

    2016-01-01

    DNA double-strand breaks (DSBs) pose a threat to genome stability and are repaired through multiple mechanisms. Rarely, telomerase, the enzyme that maintains telomeres, acts upon a DSB in a mutagenic process termed telomere healing. The probability of telomere addition is increased at specific genomic sequences termed sites of repair-associated telomere addition (SiRTAs). By monitoring repair of an induced DSB, we show that SiRTAs on chromosomes V and IX share a bipartite structure in which a core sequence (Core) is directly targeted by telomerase, while a proximal sequence (Stim) enhances the probability of de novo telomere formation. The Stim and Core sequences are sufficient to confer a high frequency of telomere addition to an ectopic site. Cdc13, a single-stranded DNA binding protein that recruits telomerase to endogenous telomeres, is known to stimulate de novo telomere addition when artificially recruited to an induced DSB. Here we show that the ability of the Stim sequence to enhance de novo telomere addition correlates with its ability to bind Cdc13, indicating that natural sites at which telomere addition occurs at high frequency require binding by Cdc13 to a sequence 20 to 100 bp internal from the site at which telomerase acts to initiate de novo telomere addition. PMID:27044869

  9. AmeriFlux CA-NS6 UCI-1989 burn site

    DOE Data Explorer

    Goulden, Mike [University of California - Irvine

    2016-01-01

    This is the AmeriFlux version of the carbon flux data for the site CA-NS6 UCI-1989 burn site. Site Description - The UCI-1989 site is located in a continental boreal forest, dominated by black spruce trees, within the BOREAS northern study area in central Manitoba, Canada. The site is a member of a chronological series of sites that are representative secondary succession growth stages after large stand replacement fires. Black spruce trees undergo a slow growth process enabling the accurate determination of the chronosequence of stand age disturbance. Additionally, boreal forests make up approximately 25% of forest ecosystems on earth. With both of these in mind, the UCI sites provide an excellent location to study the CO2 exchange between the atmosphere and boreal forest ecosystems as a function of sequential wildfires.

  10. AmeriFlux CA-NS2 UCI-1930 burn site

    DOE Data Explorer

    Goulden, Mike [University of California - Irvine

    2016-01-01

    This is the AmeriFlux version of the carbon flux data for the site CA-NS2 UCI-1930 burn site. Site Description - The UCI-1930 site is located in a continental boreal forest, dominated by black spruce trees, within the BOREAS northern study area in central Manitoba, Canada. The site is a member of a chronological series of sites that are representative secondary succession growth stages after large stand replacement fires. Black spruce trees undergo a slow growth process enabling the accurate determination of the chronosequence of stand age disturbance. Additionally, boreal forests make up approximately 25% of forest ecosystems on earth. With both of these in mind, the UCI sites provide an excellent location to study the CO2 exchange between the atmosphere and boreal forest ecosystems as a function of sequential wildfires.

  11. AmeriFlux CA-NS3 UCI-1964 burn site

    DOE Data Explorer

    Goulden, Mike [University of California - Irvine

    2016-01-01

    This is the AmeriFlux version of the carbon flux data for the site CA-NS3 UCI-1964 burn site. Site Description - The UCI-1964 site is located in a continental boreal forest, dominated by black spruce trees, within the BOREAS northern study area in central Manitoba, Canada. The site is a member of a chronological series of sites that are representative secondary succession growth stages after large stand replacement fires. Black spruce trees undergo a slow growth process enabling the accurate determination of the chronosequence of stand age disturbance. Additionally, boreal forests make up approximately 25% of forest ecosystems on earth. With both of these in mind, the UCI sites provide an excellent location to study the CO2 exchange between the atmosphere and boreal forest ecosystems as a function of sequential wildfires.

  12. AmeriFlux CA-NS7 UCI-1998 burn site

    DOE Data Explorer

    Goulden, Mike [University of California - Irvine

    2016-01-01

    This is the AmeriFlux version of the carbon flux data for the site CA-NS7 UCI-1998 burn site. Site Description - The UCI-1998 site is located in a continental boreal forest, dominated by black spruce trees, within the BOREAS northern study area in central Manitoba, Canada. The site is a member of a chronological series of sites that are representative secondary succession growth stages after large stand replacement fires. Black spruce trees undergo a slow growth process enabling the accurate determination of the chronosequence of stand age disturbance. Additionally, boreal forests make up approximately 25% of forest ecosystems on earth. With both of these in mind, the UCI sites provide an excellent location to study the CO2 exchange between the atmosphere and boreal forest ecosystems as a function of sequential wildfires.

  13. AmeriFlux CA-NS8 UCI-2003 burn site

    DOE Data Explorer

    Goulden, Mike [University of California - Irvine

    2016-01-01

    This is the AmeriFlux version of the carbon flux data for the site CA-NS8 UCI-2003 burn site. Site Description - The UCI-2003 site is located in a continental boreal forest, dominated by black spruce trees, within the BOREAS northern study area in central Manitoba, Canada. The site is a member of a chronological series of sites that are representative secondary succession growth stages after large stand replacement fires. Black spruce trees undergo a slow growth process enabling the accurate determination of the chronosequence of stand age disturbance. Additionally, boreal forests make up approximately 25% of forest ecosystems on earth. With both of these in mind, the UCI sites provide an excellent location to study the CO2 exchange between the atmosphere and boreal forest ecosystems as a function of sequential wildfires.

  14. AmeriFlux CA-NS5 UCI-1981 burn site

    DOE Data Explorer

    Goulden, Mike [University of California - Irvine

    2016-01-01

    This is the AmeriFlux version of the carbon flux data for the site CA-NS5 UCI-1981 burn site. Site Description - The UCI-1981 site is located in a continental boreal forest, dominated by black spruce trees, within the BOREAS northern study area in central Manitoba, Canada. The site is a member of a chronological series of sites that are representative secondary succession growth stages after large stand replacement fires. Black spruce trees undergo a slow growth process enabling the accurate determination of the chronosequence of stand age disturbance. Additionally, boreal forests make up approximately 25% of forest ecosystems on earth. With both of these in mind, the UCI sites provide an excellent location to study the CO2 exchange between the atmosphere and boreal forest ecosystems as a function of sequential wildfires.

  15. AmeriFlux CA-NS1 UCI-1850 burn site

    DOE Data Explorer

    Goulden, Mike [University of California - Irvine

    2016-01-01

    This is the AmeriFlux version of the carbon flux data for the site CA-NS1 UCI-1850 burn site. Site Description - The UCI-1850 site is located in a continental boreal forest, dominated by black spruce trees, within the BOREAS northern study area in central Manitoba, Canada. The site is a member of a chronological series of sites that are representative secondary succession growth stages after large stand replacement fires. Black spruce trees undergo a slow growth process enabling the accurate determination of the chronosequence of stand age disturbance. Additionally, boreal forests make up approximately 25% of forest ecosystems on earth. With both of these in mind, the UCI sites provide an excellent location to study the CO2 exchange between the atmosphere and boreal forest ecosystems as a function of sequential wildfires.

  16. Hydrogeologic applications for historical records and images from rock samples collected at the Nevada National Security Site and vicinity, Nye County, Nevada - A supplement to Data Series 297

    USGS Publications Warehouse

    Wood, David B.

    2018-03-14

    Rock samples have been collected, analyzed, and interpreted from drilling and mining operations at the Nevada National Security Site for over one-half of a century. Records containing geologic and hydrologic analyses and interpretations have been compiled into a series of databases. Rock samples have been photographed and thin sections scanned. Records and images are preserved and available for public viewing and downloading at the U.S. Geological Survey ScienceBase, Mercury Core Library and Data Center Web site at https://www.sciencebase.gov/mercury/ and documented in U.S. Geological Survey Data Series 297. Example applications of these data and images are provided in this report.

  17. Addition of a breeding database in the Genome Database for Rosaceae

    PubMed Central

    Evans, Kate; Jung, Sook; Lee, Taein; Brutcher, Lisa; Cho, Ilhyung; Peace, Cameron; Main, Dorrie

    2013-01-01

    Breeding programs produce large datasets that require efficient management systems to keep track of performance, pedigree, geographical and image-based data. With the development of DNA-based screening technologies, more breeding programs perform genotyping in addition to phenotyping for performance evaluation. The integration of breeding data with other genomic and genetic data is instrumental for the refinement of marker-assisted breeding tools, enhances genetic understanding of important crop traits and maximizes access and utility by crop breeders and allied scientists. Development of new infrastructure in the Genome Database for Rosaceae (GDR) was designed and implemented to enable secure and efficient storage, management and analysis of large datasets from the Washington State University apple breeding program and subsequently expanded to fit datasets from other Rosaceae breeders. The infrastructure was built using the software Chado and Drupal, making use of the Natural Diversity module to accommodate large-scale phenotypic and genotypic data. Breeders can search accessions within the GDR to identify individuals with specific trait combinations. Results from Search by Parentage lists individuals with parents in common and results from Individual Variety pages link to all data available on each chosen individual including pedigree, phenotypic and genotypic information. Genotypic data are searchable by markers and alleles; results are linked to other pages in the GDR to enable the user to access tools such as GBrowse and CMap. This breeding database provides users with the opportunity to search datasets in a fully targeted manner and retrieve and compare performance data from multiple selections, years and sites, and to output the data needed for variety release publications and patent applications. The breeding database facilitates efficient program management. Storing publicly available breeding data in a database together with genomic and genetic data will

  18. 31 CFR 594.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Nationals and Blocked Persons List (“SDN List”) with the identifier “[SDGT].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. Note 3 to...

  19. 31 CFR 594.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Nationals and Blocked Persons List (“SDN List”) with the identifier “[SDGT].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. See § 594.412...

  20. 31 CFR 542.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (“SDN List”) with the identifier “[SYRIA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. Note 2 to paragraph (a) of § 542.201...

  1. 31 CFR 570.201 - Prohibited transactions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Blocked Persons List (“SDN List”) with the identifier “[LIBYA2].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in Appendix A to this chapter. See § 570.406 concerning...

  2. 31 CFR 598.314 - Specially designated narcotics trafficker.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Nationals and Blocked Persons List (“SDN List”) with the identifier “[SDNTK].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. Note 2 to § 598...

  3. 31 CFR 560.211 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Blocked Persons List (“SDN List”) with the identifier “[IRAN].” The SDN List is accessible through the following page on the Office of Foreign Control's Web site: www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. See § 560.425 concerning entities that...

  4. 31 CFR 594.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Nationals and Blocked Persons List (“SDN List”) with the identifier “[SDGT].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. See § 594.412...

  5. 31 CFR 542.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (“SDN List”) with the identifier “[SYRIA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. Note 2 to paragraph (a) of § 542.201...

  6. 31 CFR 570.201 - Prohibited transactions.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Blocked Persons List (“SDN List”) with the identifier “[LIBYA2].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in Appendix A to this chapter. See § 570.406 concerning...

  7. 31 CFR 542.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (“SDN List”) with the identifier “[SYRIA].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. Note 2 to paragraph (a) of § 542.201...

  8. 31 CFR 570.201 - Prohibited transactions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Blocked Persons List (“SDN List”) with the identifier “[LIBYA2].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in Appendix A to this chapter. See § 570.406 concerning...

  9. 31 CFR 598.314 - Specially designated narcotics trafficker.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Nationals and Blocked Persons List (“SDN List”) with the identifier “[SDNTK].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. Note 2 to § 598...

  10. 31 CFR 560.211 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Blocked Persons List (“SDN List”) with the identifier “[IRAN].” The SDN List is accessible through the following page on the Office of Foreign Control's Web site: www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. See § 560.425 concerning entities that...

  11. 31 CFR 570.201 - Prohibited transactions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Blocked Persons List (“SDN List”) with the identifier “[LIBYA2].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in Appendix A to this chapter. See § 570.406 concerning...

  12. 31 CFR 598.314 - Specially designated narcotics trafficker.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Nationals and Blocked Persons List (“SDN List”) with the identifier “[SDNTK].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. Note 2 to § 598...

  13. 31 CFR 594.201 - Prohibited transactions involving blocked property.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Nationals and Blocked Persons List (“SDN List”) with the identifier “[SDGT].” The SDN List is accessible through the following page on the Office of Foreign Assets Control's Web site: http://www.treasury.gov/sdn. Additional information pertaining to the SDN List can be found in appendix A to this chapter. Note 3 to...

  14. 77 FR 68820 - Designation of Four (4) Individuals and Five (5) Entities Pursuant to Executive Order 13628 of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-16

    ... concerning OFAC are available from OFAC's Web site ( www.treasury.gov/ofac ) or via facsimile through a 24..., RASOUL), 90 Park Ave, Farahzadi St, Tehran, Iran; DOB 19 Aug 1961; POB Eghlid, Fars Province, Iran; Web site http://www.jalili.ir ; alt. Web site [[Page 68821

  15. 75 FR 17333 - Addition of National Toxicology Program Carcinogens; Community Right-to-Know Toxic Chemical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-06

    ... encryption, and be free of any defects or viruses. Docket: All documents in the docket are listed in the www... Community Right-to-Know Hotline, toll free at (800) 424-9346 or (703) 412-9810 in Virginia and Alaska or toll free, TDD (800) 553-7672, http://www.epa.gov/epaoswer/hotline/ . SUPPLEMENTARY INFORMATION: I...

  16. 15 CFR 921.33 - Boundary changes, amendments to the management plan, and addition of multiple-site components.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Reserve, may be made only after written approval by NOAA. NOAA may require public notice, including notice... statement may be required. NOAA will place a notice in the Federal Register of any proposed changes in... made. NOAA will publish notice of the proposed new site including an invitation for comments from the...

  17. 15 CFR 921.33 - Boundary changes, amendments to the management plan, and addition of multiple-site components.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Reserve, may be made only after written approval by NOAA. NOAA may require public notice, including notice... statement may be required. NOAA will place a notice in the Federal Register of any proposed changes in... made. NOAA will publish notice of the proposed new site including an invitation for comments from the...

  18. 15 CFR 921.33 - Boundary changes, amendments to the management plan, and addition of multiple-site components.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Reserve, may be made only after written approval by NOAA. NOAA may require public notice, including notice... statement may be required. NOAA will place a notice in the Federal Register of any proposed changes in... made. NOAA will publish notice of the proposed new site including an invitation for comments from the...

  19. 15 CFR 921.33 - Boundary changes, amendments to the management plan, and addition of multiple-site components.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Reserve, may be made only after written approval by NOAA. NOAA may require public notice, including notice... statement may be required. NOAA will place a notice in the Federal Register of any proposed changes in... made. NOAA will publish notice of the proposed new site including an invitation for comments from the...

  20. Use of historic metabolic biotransformation data as a means of anticipating metabolic sites using MetaPrint2D and Bioclipse.

    PubMed

    Carlsson, Lars; Spjuth, Ola; Adams, Samuel; Glen, Robert C; Boyer, Scott

    2010-07-01

    Predicting metabolic sites is important in the drug discovery process to aid in rapid compound optimisation. No interactive tool exists and most of the useful tools are quite expensive. Here a fast and reliable method to analyse ligands and visualise potential metabolic sites is presented which is based on annotated metabolic data, described by circular fingerprints. The method is available via the graphical workbench Bioclipse, which is equipped with advanced features in cheminformatics. Due to the speed of predictions (less than 50 ms per molecule), scientists can get real time decision support when editing chemical structures. Bioclipse is a rich client, which means that all calculations are performed on the local computer and do not require network connection. Bioclipse and MetaPrint2D are free for all users, released under open source licenses, and available from http://www.bioclipse.net.