36 CFR 906.5 - Administration of affirmative action plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... CORPORATION AFFIRMATIVE ACTION POLICY AND PROCEDURE Development Program § 906.5 Administration of affirmative action plan. (a) The developer shall appoint an Affirmative Action Officer, and for projects exceeding $10 million in cost, the person appointed must have affirmative action as a primary responsibility. (b...

Errors in preparation and administration of parenteral drugs in neonatology: evaluation and corrective actions.

PubMed

Hasni, Nesrine; Ben Hamida, Emira; Ben Jeddou, Khouloud; Ben Hamida, Sarra; Ayadi, Imene; Ouahchi, Zeineb; Marrakchi, Zahra

2016-12-01

The medication iatrogenic risk is quite unevaluated in neonatology Objective: Assessment of errors that occurred during the preparation and administration of injectable medicines in a neonatal unit in order to implement corrective actions to reduce the occurrence of these errors. A prospective, observational study was performed in a neonatal unit over a period of one month. The practice of preparing and administering injectable medications were identified through a standardized data collection form. These practices were compared with summaries of the characteristics of each product (RCP) and the bibliography. One hundred preparations were observed of 13 different drugs. 85 errors during preparations and administration steps were detected. These errors were divided into preparation errors in 59% of cases such as changing the dilution protocol (32%), the use of bad solvent (11%) and administration errors in 41% of cases as errors timing of administration (18%) or omission of administration (9%). This study showed a high rate of errors during stages of preparation and administration of injectable drugs. In order to optimize the care of newborns and reduce the risk of medication errors, corrective actions have been implemented through the establishment of a quality assurance system which consisted of the development of injectable drugs preparation procedures, the introduction of a labeling system and staff training.

40 CFR 77.4 - Administrator's action on proposed offset plans.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Administrator's action on proposed offset plans. 77.4 Section 77.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) EXCESS EMISSIONS § 77.4 Administrator's action on proposed offset plans. (a...

40 CFR 78.6 - Action on petition for administrative review.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Action on petition for administrative review. 78.6 Section 78.6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPEAL PROCEDURES § 78.6 Action on petition for administrative review. (a) If no...

Effect of mode of administration on guaifenesin pharmacokinetics and expectorant action in the rat model.

PubMed

Kagan, Leonid; Lavy, Eran; Hoffman, Amnon

2009-06-01

Guaifenesin is a very commonly used and prescribed oral expectorant drug. However, its mechanism of action is not completely elucidated and the available information is limited. The purpose was to evaluate whether guaifenesin action on respiratory tract secretion is mediated through a reflex stimulation of the gastric mucosa or by the systemic exposure due to the absorption of the drug to the blood circulation. Guaifenesin was administered to rats by various routes: intravenous bolus, oral gavage, and gastric, jejunal or cecal infusions (through surgically implanted catheters). Phenol red respiratory tract secretion (after intraperitoneal or intravenous injection) was used as a marker for degree of expectorant action. Administration of saline by gavage was used as control. Respiratory secretion following oral bolus was approximately 2-fold higher (p<0.05) than that of control. Following IV administration the increase of respiratory secretion did not occur despite the fact that systemic exposure to guaifenesin was 1.5-fold higher than following oral administration. The abdominal surgery was found to eliminate the effect of guaifenesin although it did not change systemic absorption. Guaifenesin was equally absorbed from all parts of the gastrointestinal tract. It was demonstrated that expectorant action of guaifenesin is mediated by stimulation of the gastrointestinal tract and not by the systemic exposure to the drug.

32 CFR 513.3 - Administrative and punitive actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Administrative and punitive actions. 513.3 Section 513.3 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS INDEBTEDNESS OF MILITARY PERSONNEL § 513.3 Administrative and punitive...

45 CFR 689.8 - Interim administrative actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... RESEARCH MISCONDUCT § 689.8 Interim administrative actions. (a) After an inquiry or during an external or... misconduct. Such an order will normally be issued on recommendation from OIG and in consultation with the...

45 CFR 689.8 - Interim administrative actions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... RESEARCH MISCONDUCT § 689.8 Interim administrative actions. (a) After an inquiry or during an external or... misconduct. Such an order will normally be issued on recommendation from OIG and in consultation with the...

45 CFR 689.8 - Interim administrative actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... RESEARCH MISCONDUCT § 689.8 Interim administrative actions. (a) After an inquiry or during an external or... misconduct. Such an order will normally be issued on recommendation from OIG and in consultation with the...

45 CFR 689.8 - Interim administrative actions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... RESEARCH MISCONDUCT § 689.8 Interim administrative actions. (a) After an inquiry or during an external or... misconduct. Such an order will normally be issued on recommendation from OIG and in consultation with the...

45 CFR 689.8 - Interim administrative actions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... RESEARCH MISCONDUCT § 689.8 Interim administrative actions. (a) After an inquiry or during an external or... misconduct. Such an order will normally be issued on recommendation from OIG and in consultation with the...

42 CFR 8.34 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Court review of final administrative action; exhaustion of administrative remedies. 8.34 Section 8.34 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures for...

42 CFR 8.34 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Court review of final administrative action; exhaustion of administrative remedies. 8.34 Section 8.34 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures for...

42 CFR 8.34 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Court review of final administrative action; exhaustion of administrative remedies. 8.34 Section 8.34 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures for...

40 CFR 300.820 - Administrative record file for a removal action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.820 Administrative record file for a removal action. (a) If, based on the site evaluation, the lead agency determines... public comment. At such time, the lead agency shall publish in a major local newspaper of general...

40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean Water Act. Unless the Administrator otherwise...

21 CFR 10.45 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 12. (b) A request that the Commissioner take or refrain from taking any form of administrative action... review of final agency action; and (iii) It is not appropriate to move to dismiss a suit for... that it is an unconsented suit against the United States if the defect could be cured by amending the...

21 CFR 10.45 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 12. (b) A request that the Commissioner take or refrain from taking any form of administrative action... review of final agency action; and (iii) It is not appropriate to move to dismiss a suit for... that it is an unconsented suit against the United States if the defect could be cured by amending the...

21 CFR 10.45 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 12. (b) A request that the Commissioner take or refrain from taking any form of administrative action... review of final agency action; and (iii) It is not appropriate to move to dismiss a suit for... that it is an unconsented suit against the United States if the defect could be cured by amending the...

21 CFR 10.45 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 12. (b) A request that the Commissioner take or refrain from taking any form of administrative action... review of final agency action; and (iii) It is not appropriate to move to dismiss a suit for... that it is an unconsented suit against the United States if the defect could be cured by amending the...

12 CFR 615.5361 - Relation to other administrative actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Relation to other administrative actions. 615.5361 Section 615.5361 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM FUNDING AND FISCAL AFFAIRS, LOAN POLICIES AND OPERATIONS, AND FUNDING OPERATIONS Issuance of a Capital Directive...

40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean Water...

40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean Water...

40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean Water...

40 CFR 23.2 - Timing of Administrator's action under Clean Water Act.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under Clean Water Act. 23.2 Section 23.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.2 Timing of Administrator's action under Clean Water...

42 CFR 93.407 - HHS administrative actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.407 HHS administrative actions. (a) In response to a research misconduct proceeding... Subparts 9.4 and 309.4, or both. (b) In connection with findings of research misconduct, HHS also may seek...

42 CFR 8.34 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures for... Withdrawal of Approval of an Accreditation Body § 8.34 Court review of final administrative action...

42 CFR 8.34 - Court review of final administrative action; exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF OPIOID TREATMENT PROGRAMS Procedures for... Withdrawal of Approval of an Accreditation Body § 8.34 Court review of final administrative action...

23 CFR 810.208 - Action by the Federal Highway Administrator.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Action by the Federal Highway Administrator. 810.208 Section 810.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS Making Highway Rights-of-Way Available for Mass...

23 CFR 810.208 - Action by the Federal Highway Administrator.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Action by the Federal Highway Administrator. 810.208 Section 810.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS Making Highway Rights-of-Way Available for Mass...

23 CFR 810.208 - Action by the Federal Highway Administrator.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false Action by the Federal Highway Administrator. 810.208 Section 810.208 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PUBLIC TRANSPORTATION MASS TRANSIT AND SPECIAL USE HIGHWAY PROJECTS Making Highway Rights-of-Way Available for Mass...

20 CFR 408.1003 - Which administrative actions are initial determinations?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Which administrative actions are initial determinations? 408.1003 Section 408.1003 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR...) Our calculation of the amount of change in your federally administered State recognition payment...

24 CFR 25.6 - Violations creating grounds for administrative action.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Violations creating grounds for administrative action. 25.6 Section 25.6 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development MORTGAGEE REVIEW BOARD § 25.6 Violations creating grounds for administrative...

21 CFR 516.123 - Informal conferences regarding agency administrative actions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... exemption, determining that a qualified expert panel does not meet the selection criteria, denying a request... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Informal conferences regarding agency administrative actions. 516.123 Section 516.123 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH...

32 CFR 516.66 - Administrative and contractual actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Administrative and contractual actions. 516.66 Section 516.66 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.66...

75 FR 43537 - Mortgagee Review Board: Administrative Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-26

...., Fountain Valley, CA. 469. Ironwood Lending, Inc., Phoenix, AZ. 470. IVC Mortgage Group, Inc., Des Plaines..., connected, or had authorization from HUD for its Web site. 3. Americare Investment Group, Inc. d/b/a Premier... Notice of Administrative Action to Americare Investment Group, Inc. (Americare) permanently withdrawing...

32 CFR 516.66 - Administrative and contractual actions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 3 2011-07-01 2009-07-01 true Administrative and contractual actions. 516.66 Section 516.66 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.66...

40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless the...

Help Teachers Engage Students: Action Tools for Administrators

ERIC Educational Resources Information Center

Brinkman, Annette; Forlini, Gary; Williams, Ellen

2009-01-01

This unique, hands-on reference for school administrators offers guidelines for effective student engagement as well as reproducible action tools that will enable you to: (1) Identify and share "The Big Eight Student Engagement Strategies" with your teachers; (2) Promote teacher growth and provide support for new and/or struggling teachers; (3)…

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

40 CFR 300.815 - Administrative record file for a remedial action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... SUBSTANCES POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.815... investigation phase. At such time, the lead agency shall publish in a major local newspaper of general circulation a notice of the availability of the administrative record file. (b) The lead agency shall provide...

20 CFR 408.1004 - Which administrative actions are not initial determinations?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Which administrative actions are not initial determinations? 408.1004 Section 408.1004 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SPECIAL BENEFITS FOR... federally administered State recognition payments due to a State-initiated mass change, as defined in § 408...

Institutional Image: The Concept and Implications for Administrative Action.

ERIC Educational Resources Information Center

Renihan, Frederick I; Renihan, Patrick J.

1989-01-01

Explores institutional image as a key to providing a philosophy and a logical foundation for school improvement efforts. Identifies two image dimensions (cosmetic and pastoral) and classifies five school types (synergistic, candy store, disaffected, monastic, and survivor), and discusses implications for administrative action. Includes three…

The relative advantages of criminal versus administrative environmental enforcement actions in Israel.

PubMed

Tal, Alon; Aharon, Yaara; Yuhas-Peled, Hadar

2010-04-01

Most environmental enforcement programs have separate criminal and administrative procedures for addressing violations. Pitting "criminal"versus"administrative" enforcement as mutually exclusive alternatives constitutes a "false dilemma". Clearly, the government response should be influenced by the severity of pollution and the specific circumstances of the polluter. Yet, policy makers seeking to improve environmental compliance need to have a clearer picture about the merits of each approach and their relative effectiveness. This research empirically assesses the effectiveness of criminal versus administrative enforcement activities in Israel. After considering the philosophical implications associated with each regulatory approach, the results of a year-long study are presented. A series of performance indicators are utilized, with particular weight on compliance status in the field, to assess the condition of environmental violations several years subsequent to completion of enforcement activities. The state of 100 violations of air, water and hazardous materials laws that had been addressed through the criminal process were matched with results of comparable violations, against which administrative actions were taken. Results suggest that while criminal enforcement is a longer process, compliance following these actions was significantly greater than in administrative enforcement cases. The findings also underline the significance of a systematic follow-up system for tracking violations after enforcement actions are complete. Finally, the study confirms the benefits of targeted assistance to improve compliance among violators of environmental standards.

40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the Administrator...

40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the Administrator...

40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the Administrator...

40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the Administrator...

40 CFR 23.8 - Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. 23.8 Section 23.8 Protection of Environment... Administrator's action under Uranium Mill Tailings Radiation Control Act of 1978. Unless the Administrator...

40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise explicitly...

40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise explicitly...

40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise explicitly...

40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise explicitly...

40 CFR 23.10 - Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under the Federal Food, Drug, and Cosmetic Act. 23.10 Section 23.10 Protection of Environment ENVIRONMENTAL... action under the Federal Food, Drug, and Cosmetic Act. Unless the Administrator otherwise explicitly...

40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless the Administrator otherwise explicitly provides in a particular promulgation...

40 CFR 23.7 - Timing of Administrator's action under Safe Drinking Water Act.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Safe Drinking Water Act. 23.7 Section 23.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL JUDICIAL REVIEW UNDER EPA-ADMINISTERED STATUTES § 23.7 Timing of Administrator's action under Safe Drinking Water Act. Unless the Administrator otherwise explicitly provides in a particular promulgation...

Anticipation of delayed action-effects: learning when an effect occurs, without knowing what this effect will be.

PubMed

Dignath, David; Janczyk, Markus

2017-09-01

According to the ideomotor principle, behavior is controlled via a retrieval of the sensory consequences that will follow from the respective movement ("action-effects"). These consequences include not only what will happen, but also when something will happen. In fact, recollecting the temporal duration between response and effect takes time and prolongs the initiation of the response. We investigated the associative structure of action-effect learning with delayed effects and asked whether participants acquire integrated action-time-effect episodes that comprise a compound of all three elements or whether they acquire separate traces that connect actions to the time until an effect occurs and actions to the effects that follow them. In three experiments, results showed that participants retrieve temporal intervals that follow from their actions even when the identity of the effect could not be learned. Furthermore, retrieval of temporal intervals in isolation was not inferior to retrieval of temporal intervals that were consistently followed by predictable action-effects. More specifically, when tested under extinction, retrieval of action-time and action-identity associations seems to compete against each other, similar to overshadowing effects reported for stimulus-response conditioning. Together, these results suggest that people anticipate when the consequences of their action will occur, independently from what the consequences will be.

40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the time...

40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the time...

40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the time...

40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the time...

40 CFR 23.9 - Timing of Administrator's action under the Atomic Energy Act.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Timing of Administrator's action under the Atomic Energy Act. 23.9 Section 23.9 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Atomic Energy Act. Unless the Administrator otherwise explicitly provides in a particular order, the time...

32 CFR 636.5 - Army administrative actions against intoxicated drivers.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 4 2010-07-01 2010-07-01 true Army administrative actions against intoxicated drivers. 636.5 Section 636.5 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION (SPECIFIC INSTALLATIONS) Fort Stewart, Georgia § 636.5...

15 CFR 720.3 - Final decision on administrative action denying export privileges.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS DENIAL OF EXPORT PRIVILEGES § 720.3 Final decision on administrative action...

15 CFR 720.3 - Final decision on administrative action denying export privileges.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS DENIAL OF EXPORT PRIVILEGES § 720.3 Final decision on administrative action...

Noribogaine, but not 18-MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self-administration

PubMed Central

Carnicella, Sebastien; He, Dao-Yao; Yowell, Quinn V.; Glick, Stanley D.; Ron, Dorit

2013-01-01

Ibogaine is a naturally occurring alkaloid that has been reported to decrease various adverse phenotypes associated with exposure to drugs of abuse and alcohol in human and rodent models. Unfortunately, ibogaine cannot be used as a medication to treat addiction because of severe side effects. Previously, we reported that the desirable actions of ibogaine to reduce self-administration of, and relapse to, alcohol consumption are mediated via the upregulation of the expression of the glial cell line-derived neurotrophic factor (GDNF) in the midbrain ventral tegmental area (VTA), and the consequent activation of the GDNF pathway. The ibogaine metabolite, noribogaine, and a synthetic derivative of ibogaine, 18-Methoxycoronaridine (18-MC), possess a similar anti-addictive profile as ibogaine in rodent models, but without some of its adverse side effects. Here, we determined whether noribogaine and/or 18-MC, like ibogaine, increase GDNF expression, and whether their site of action to reduce alcohol consumption is the VTA. We used SH-SY5Y cells as a cell culture model and found that noribogaine, like ibogaine, but not 18-MC, induces a robust increase in GDNF mRNA levels. Next, we tested the effect of intra-VTA infusion of noribogaine and 18-MC on rat operant alcohol self-administration and found that noribogaine, but not 18-MC, in the VTA decreases responding for alcohol. Together, our results suggest that noribogaine and 18-MC have different mechanisms and sites of action. PMID:21040239

78 FR 277 - Food and Drug Administration Actions Related to Nicotine Replacement Therapies and Smoking...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-03

... Dependence; Public Hearing; Extension of Comment Period AGENCY: Food and Drug Administration, HHS. ACTION: Notification of public hearing; Extension of comment period. SUMMARY: The Food and Drug Administration (FDA) is... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 15 [Docket No...

15 CFR 720.2 - Initiation of administrative action denying export privileges.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Initiation of administrative action denying export privileges. 720.2 Section 720.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS...

15 CFR 720.2 - Initiation of administrative action denying export privileges.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 15 Commerce and Foreign Trade 2 2011-01-01 2011-01-01 false Initiation of administrative action denying export privileges. 720.2 Section 720.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE CHEMICAL WEAPONS...

Noribogaine, but not 18-MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self-administration.

PubMed

Carnicella, Sebastien; He, Dao-Yao; Yowell, Quinn V; Glick, Stanley D; Ron, Dorit

2010-10-01

Ibogaine is a naturally occurring alkaloid that has been reported to decrease various adverse phenotypes associated with exposure to drugs of abuse and alcohol in human and rodent models. Unfortunately, ibogaine cannot be used as a medication to treat addiction because of severe side effects. Previously, we reported that the desirable actions of ibogaine to reduce self-administration of, and relapse to, alcohol consumption are mediated via the upregulation of the expression of the glial cell line-derived neurotrophic factor (GDNF) in the midbrain ventral tegmental area (VTA), and the consequent activation of the GDNF pathway. The ibogaine metabolite, noribogaine, and a synthetic derivative of ibogaine, 18-Methoxycoronaridine (18-MC), possess a similar anti-addictive profile as ibogaine in rodent models, but without some of its adverse side effects. Here, we determined whether noribogaine and/or 18-MC, like ibogaine, increase GDNF expression, and whether their site of action to reduce alcohol consumption is the VTA. We used SH-SY5Y cells as a cell culture model and found that noribogaine, like ibogaine, but not 18-MC, induces a robust increase in GDNF mRNA levels. Next, we tested the effect of intra-VTA infusion of noribogaine and 18-MC on rat operant alcohol self-administration and found that noribogaine, but not 18-MC, in the VTA decreases responding for alcohol. Together, our results suggest that noribogaine and 18-MC have different mechanisms and sites of action. © 2010 The Authors, Addiction Biology © 2010 Society for the Study of Addiction.

Nursing Academic Administrators' Lived Experiences With Incivility and Bullying From Faculty: Consequences and Outcomes Demanding Action.

PubMed

LaSala, Kathleen B; Wilson, Vicki; Sprunk, Elizabeth

2016-01-01

There are an increasing number of nursing academic administrators who identify themselves as victims of faculty incivility. This study examined experiences that academic administrators encountered with faculty incivility using a phenomenological research design. Three major themes emerged: faculty inappropriate behaviors, consequences of faculty behaviors on administrator targets, and administrators call for action. Findings revealed that incivility had devastating effects on administrators personally and professionally.

School Administrator Perceptions of Cyberbullying Facilitators and Barriers to Preventive Action: A Qualitative Study.

PubMed

Young, Rachel; Tully, Melissa; Ramirez, Marizen

2017-06-01

Schools are often held responsible for preventing or addressing cyberbullying, yet little is known about school administrator perceptions of cyberbullying and the challenges they face in addressing this public health issue. The goal of this study is to examine school administrators' perceptions of the facilitators of cyberbullying and barriers to primary and secondary prevention strategies. Public school administrators ( N = 36) participated in in-depth interviews about bullying and discussed their experiences with cyberbullying and their perceptions of cyberbullying facilitators and barriers to prevention. Three main themes arose from the analysis: (1) cyberbullying as a major challenge; (2) facilitators of cyberbullying and barriers to preventive action, including parents and technology; and (3) prevention efforts, including unclear jurisdiction for action, primary versus secondary prevention efforts, and technology attributes that facilitate school response to bullying. Although administrators perceive cyberbullying as a major challenge facing their schools, they are often unsure about appropriate primary and secondary prevention efforts. Relationships with parents and police complicate response and prevention as schools attempt to navigate unclear jurisdiction. Additionally, technology presents a challenge to schools because it is seen as an enabler of cyberbullying, a facilitator of prevention, and a necessary part of education efforts. Lack of research on prevention strategies, parents' knowledge and attitudes, and confusion about responsibility for addressing cyberbullying are barriers to action. Findings suggest administrators could benefit from additional clarity on which strategies are most effective for primary prevention of cyberbullying, and that prevention strategies should proactively involve parents to promote effective collaboration with schools.

42 CFR 456.524 - Notification of Administrator's action and duration of variance.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL ASSISTANCE PROGRAMS UTILIZATION CONTROL Utilization Review Plans: FFP, Waivers, and Variances for Hospitals and Mental Hospitals Ur Plan: Remote Facility Variances from Time Requirements § 456.524 Notification of Administrator's action and duration of...

Electroporation-delivered transdermal neostigmine in rats: equivalent action to intravenous administration

PubMed Central

Berkó, Szilvia; Szűcs, Kálmán F; Balázs, Boglárka; Csányi, Erzsébet; Varju, Gábor; Sztojkov-Ivanov, Anita; Budai-Szűcs, Mária; Bóta, Judit; Gáspár, Róbert

2016-01-01

Purpose Transdermal electroporation has become one of the most promising noninvasive methods for drug administration, with greatly increased transport of macromolecules through the skin. The cecal-contracting effects of repeated transdermal electroporation delivery and intravenous administration of neostigmine were compared in anesthetized rats. Methods The cecal contractions were detected with implantable strain gauge sensors, and the plasma levels of neostigmine were followed by high-performance liquid chromatography. Results Both intravenously and EP-administered neostigmine (0.2–66.7 μg/kg) increased the cecal contractions in a dose-dependent manner. For both the low doses and the highest dose, the neostigmine plasma concentrations were the same after the two modes of administration, while an insignificantly higher level was observed at a dose of 20 μg/kg after intravenous administration as compared with the electroporation route. The contractile responses did not differ significantly after the two administration routes. Conclusion The results suggest that electroporation-delivered neostigmine elicits action equivalent to that observed after intravenous administration as concerning both time and intensity. Electroporation permits the delivery of even lower doses of water-soluble compounds through the skin, which is very promising for clinical practice. PMID:27274203

42 CFR 457.203 - Administrative and judicial review of action on State plan material.

Code of Federal Regulations, 2010 CFR

2010-10-01

... determines that his or her original decision was incorrect, CMS will pay the State a lump sum equal to any... with the Administrator's action on State plan material under § 457.150 may, within 60 days after... of hearing. Within 30 days after receipt of the request, the Administrator notifies the State of the...

42 CFR 93.408 - Mitigating and aggravating factors in HHS administrative actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Mitigating and aggravating factors in HHS administrative actions. 93.408 Section 93.408 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES...

42 CFR 93.408 - Mitigating and aggravating factors in HHS administrative actions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Mitigating and aggravating factors in HHS administrative actions. 93.408 Section 93.408 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES...

42 CFR 93.408 - Mitigating and aggravating factors in HHS administrative actions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Mitigating and aggravating factors in HHS administrative actions. 93.408 Section 93.408 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES...

42 CFR 93.408 - Mitigating and aggravating factors in HHS administrative actions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Mitigating and aggravating factors in HHS administrative actions. 93.408 Section 93.408 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES...

Administrators in Action--Managing Public Monies and Processing Emotion in School Activities: A Teaching Case Study

ERIC Educational Resources Information Center

Tenuto, Penny L.; Gardiner, Mary E.; Yamamoto, Julie K.

2015-01-01

This teaching case describes school administrators in action performing day-to-day leadership tasks, managing public funds in school activities, and interacting with others appropriately. The case focuses on administrative challenges in handling and managing school activity funds. A method for processing emotion is discussed to assist…

Neurohumoral mechanism in the natriuretic action of intracerebroventricular administration of renin.

PubMed

Zavala, Lida; Barbella, Yarisma; Israel, Anita

2004-03-01

Intracerebroventricular (i.v.t.) administration of renin (R) decreases urinary volume and increases urinary sodium excretion. We investigated whether i.v.t.-R-induced natriuresis could be associated with the release of atrial natriuretic peptide (ANP), its interaction with renal ANP-A receptors (ANPR-A) and the subsequent increase of urinary cyclic 3-5 guanosine monophosphate (cGMP). In i.v.t. cannulated rats, the left carotid artery was catheterised with PE-50 tubing for blood collection, renin was injected i.v.t. and arterial blood samples were collected at 0, 2, 5, 10 and 15 minutes of injection, and urinary sodium and cGMP excretion at 1-, 3- and 6-hour periods of urine collection. Plasma ANP levels and urinary cGMP were determined by radioimmunoassay, and each urine sample was analysed for sodium concentration using a flame photometer. Our results demonstrate that i.v.t.-R administration increases plasma ANP levels after two minutes of injection and urinary cGMP concentration at 1-, 3- and 6 hour period of urine collection. The natriuretic action induced by i.v.t.-R was blunted by peripheral administration of anantin, an ANPR-A antagonist. We assessed the role of brain angiotensin II (Ang II) AT1-receptors on the i.v.t.-induced antidiuresis, natriuresis and cGMP urinary excretion, the last as an indirect index of ANP secretion. Blockade of brain Ang II AT1-receptors with losartan (LOS; 120 microg/3 microl, i.v.t.), inhibited the antidiuretic action and blocked the increased urinary sodium and cGMP excretion induced by i.v.t.-R (7.14 mGU/5 microl). The increase in urinary cGMP was independent of nitric oxide synthase stimulation, since L-NAME pre-treatment did not alter the renal actions induced by i.v.t.-R. Our results suggest that there is a link between the brain and the kidney. The activation of brain angiotensinergic neurons and stimulation of AT1- receptors may stimulate the release of ANP to the circulation. The released ANP circulates to the kidneys

20 CFR 667.800 - What actions of the Department may be appealed to the Office of Administrative Law Judges?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false What actions of the Department may be appealed to the Office of Administrative Law Judges? 667.800 Section 667.800 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR ADMINISTRATIVE PROVISIONS UNDER TITLE I OF THE WORKFORCE INVESTMENT ACT Administrative Adjudication...

10 CFR 10.33 - Action by the Deputy Executive Director for Information Services and Administration and Chief...

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 1 2011-01-01 2011-01-01 false Action by the Deputy Executive Director for Information Services and Administration and Chief Information Officer. 10.33 Section 10.33 Energy NUCLEAR REGULATORY... SECURITY INFORMATION OR AN EMPLOYMENT CLEARANCE Procedures § 10.33 Action by the Deputy Executive Director...

10 CFR 10.33 - Action by the Deputy Executive Director for Information Services and Administration and Chief...

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 1 2012-01-01 2012-01-01 false Action by the Deputy Executive Director for Information Services and Administration and Chief Information Officer. 10.33 Section 10.33 Energy NUCLEAR REGULATORY... SECURITY INFORMATION OR AN EMPLOYMENT CLEARANCE Procedures § 10.33 Action by the Deputy Executive Director...

Fetal radiation dose estimates for I-131 sodium iodide in cases where conception occurs after administration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sparks, R.B.; Stabin, M.G.

1999-01-01

After administration of I-131 to the female patient, the possibility of radiation exposure of the embryo/fetus exists if the patient becomes pregnant while radioiodine remains in the body. Fetal radiation dose estimates for such cases were calculated. Doses were calculated for various maternal thyroid uptakes and time intervals between administration and conception, including euthyroid and hyperthyroid cases. The maximum fetal dose calculating was about 9.8E-03 mGy/MBq, which occurred with 100% maternal thyroid uptake and a 1 week interval between administration and conception. Placental crossover of the small amount of radioiodine remaining 90 days after conception was also considered. Such crossovermore » could result in an additional fetal dose of 9.8E-05 mGy/MBq and a maximum fetal thyroid self dose of 3.5E-04 mGy/MBq.« less

Phytohormonal basis for the plant growth promoting action of naturally occurring biostimulators.

PubMed

Kurepin, Leonid V; Zaman, Mohammad; Pharis, Richard P

2014-07-01

There is increasing interest in the use of naturally occurring 'biostimulators' for enhancing the growth of agricultural and horticultural crops. Bacteria, fungi and protozoa, as well as marine algae-based seaweed extracts, can produce or contain biostimulators. The activity of biostimulators to promote plant growth is often attributed to their ability to directly or indirectly provide mineral nutrients (mostly N, but also P, S and other macro- and micro-nutrients) to plants. Alternatively, biostimulators are postulated to increase the plant's ability to assimilate these mineral nutrients, often in return for photo-assimilates (as occurs with certain bacteria and fungi associations). Although optimal growth of plants depends on the availability of adequate mineral nutritients, that growth (and also development, including reproduction) is also regulated by plant hormones (phytohormones), including gibberellins, auxins and cytokinins. This review describes and discusses the evidence that the presence or application of biostimulators also increases plant growth directly via phytohormone action and also influences the plant's ability to control its own hormone biosynthesis and homeostasis. Finally, it discusses the need for a better understanding of the role(s) that are played by the naturally occurring biostimulators associated with the plant in the crop field. It is suggested that better understanding will allow for optimal crop yield returns, since disruptions of phytohormone homeostasis in plant organs and tissues can yield either beneficial or sub-optimal outcomes. © 2013 Society of Chemical Industry.

Attitudes of Faculty and Administrators Toward Affirmative Action in Higher Education; A Second Look.

ERIC Educational Resources Information Center

Maca, Suanne D.

This dissertation investigated six indications of change regarding affirmative action efforts on the University of Texas at Austin campus since December, 1973. These indications of change were recorded in university personnel documents, EEO/AA Office records, and the results of a questionnaire submitted to the faculty and administrators of the…

12 CFR 513.6 - Duty to file information concerning adverse judicial or administrative action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Duty to file information concerning adverse judicial or administrative action. 513.6 Section 513.6 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY PRACTICE BEFORE THE OFFICE § 513.6 Duty to file information concerning adverse...

Hypophosphatemia occurs with insulin administration during refeeding by total parenteral nutrition in rats.

PubMed

Kawamura, Hiromi; Tanaka, Sarasa; Uenami, Yuri; Tani, Mariko; Ishitani, Midori; Morii, Saeko; Sakaue, Motoyoshi; Ito, Mikiko

2018-01-01

Refeeding syndrome (RFS) is characterized by the metabolic and clinical changes that occur following aggressive nutritional supplementation in malnourished patients. Hypophosphatemia is the hallmark of RFS and is key to its prevention and treatment in clinical practice. However, the mechanism of hypophosphatemia during RFS is unclear because of the lack of an animal model. In this study, we developed a rat RFS model as a first step to clarifying the molecular mechanism. After establishing the parenteral route, rats were fasted for 5 days and refeeding was started using total parenteral nutrition. The animals were infused with a high calorie solution with or without insulin administration. Results showed that plasma phosphate levels did not decrease in rats infused with the high calorie solution alone;in contrast, a 20% reduction compared to baseline was observed in rats administered insulin. In addition, rats infused with the high calorie solution containing added phosphate did not present with hypophosphatemia. Thus, we developed a rat RFS model with hypophosphatemia by tube feeding and insulin administration, and demonstrated the importance of phosphate in preventing refeeding hypophosphatemia. J. Med. Invest. 65:50-55, February, 2018.

Technology assessment and citizen action

NASA Technical Reports Server (NTRS)

Mottur, E. R.

1972-01-01

The importance of citizen participation in the assessment process is discussed, and a system for citizen assessment action is proposed. A national assessment system is outlined. Citizen participation is considered essential in the assessment process, and impediments to effective action taken by citizens are discussed. These impediments are finance, organization and motivation, and information. The establishment of citizens' assessment associations is proposed, whose functioning would be fostered and regulated by the Citizens' Assessment Administration. The organization, functions, and financing of these associations are described. The implications of citizen action are indicated as the extensive use of class action suits, the broad interpretation of associated costs of litigation, and the use of present scientific research as evidence to assert that it is reasonable to conclude that certain consequences are probable to occur in the future.

Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration.

PubMed

Bannenberg, Gerard; Moussignac, Rose-Laure; Gronert, Karsten; Devchand, Pallavi R; Schmidt, Birgitta A; Guilford, William J; Bauman, John G; Subramanyam, Babu; Perez, H Daniel; Parkinson, John F; Serhan, Charles N

2004-09-01

1. Lipoxins (LX) and aspirin-triggered 15-epi-lipoxins (ATL) exert potent anti-inflammatory actions. In the present study, we determined the anti-inflammatory efficacy of endogenous LXA(4) and LXB(4), the stable ATL analog ATLa2, and a series of novel 3-oxa-ATL analogs (ZK-996, ZK-990, ZK-994, and ZK-142) after intravenous, oral, and topical administration in mice. 2. LXA(4), LXB(4), ATLa2, and ZK-994 were orally active, exhibiting potent systemic inhibition of zymosan A-induced peritonitis at very low doses (50 ng kg(-1)-50 microg kg(-1)). 3. Intravenous ZK-994 and ZK-142 (500 microg kg(-1)) potently attenuated hind limb ischemia/reperfusion-induced lung injury, with 32+/-12 and 53+/-5% inhibition (P<0.05), respectively, of neutrophil accumulation in lungs. The same dose of ATLa2 had no significant protective action. 4. Topical application of ATLa2, ZK-994, and ZK-142 ( approximately 20 microg cm(-2)) prevented vascular leakage and neutrophil infiltration in LTB(4)/PGE(2)-stimulated ear skin inflammation. While ATLa2 and ZK-142 displayed approximately equal anti-inflammatory efficacy in this model, ZK-994 displayed a slower onset of action. 5. In summary, native LXA(4) and LXB(4), and analogs ATLa2, ZK-142, and ZK-994 retain broad anti-inflammatory effects after intravenous, oral, and topical administration. The 3-oxa-ATL analogs, which have enhanced metabolic and chemical stability and a superior pharmacokinetic profile, provide new opportunities to explore the actions and therapeutic potential for LX and ATL.

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

20 CFR 422.445 - May we bring a civil action against your employer for failure to comply with our administrative...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false May we bring a civil action against your employer for failure to comply with our administrative wage garnishment order? 422.445 Section 422.445 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ORGANIZATION AND PROCEDURES Collection of Debts by...

Taking Action: Ideas To Promote Technology Integration [and] Administrator's Desk Reference: Readings To Promote Technology Integration. Technology Integration: A Thematic Focus.

ERIC Educational Resources Information Center

Thormann, Joan, Ed.; And Others

This guide for school administrators interested in technology integration in the curriculum was developed from discussions at the Technology Integration Seminar held in March, 1991. The guide is divided into five chapters covering various administrative responsibilities and action steps. The first chapter presents an overview and identifies…

10 CFR 10.33 - Action by the Deputy Executive Director for Information Services and Administration and Chief...

Code of Federal Regulations, 2010 CFR

2010-01-01

... well as the unfavorable information concerning the individual and shall take into account the value of... 10 Energy 1 2010-01-01 2010-01-01 false Action by the Deputy Executive Director for Information Services and Administration and Chief Information Officer. 10.33 Section 10.33 Energy NUCLEAR REGULATORY...

Collaborative Developmental Action Inquiry: An Opportunity for Transformative Learning to Occur?

ERIC Educational Resources Information Center

Nicolaides, Aliki; Dzubinski, Leanne

2016-01-01

Life in the 21st century is increasingly complex, paradoxical, and ambiguous, bringing into question the ways that graduate adult education programs function. In this article, we describe an action research study involving the method of collaborative developmental action inquiry conducted with key stakeholders of a program in adult education at a…

15 CFR 922.50 - Appeals of administrative action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL... Administrator for Ocean Services and Coastal Zone Management, NOAA 1305 East-West Highway, 13th Floor, Silver Spring, MD 20910. (c)(1) The Assistant Administrator may request the appellant to submit such information...

15 CFR 922.50 - Appeals of administrative action.

Code of Federal Regulations, 2011 CFR

2011-01-01

... (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OCEAN AND COASTAL... Administrator for Ocean Services and Coastal Zone Management, NOAA 1305 East-West Highway, 13th Floor, Silver Spring, MD 20910. (c)(1) The Assistant Administrator may request the appellant to submit such information...

Conqueror and Administrator: Civil and Military Actions of Marshall Louis-Gabriel Suchet in the Spanish Province of Aragon, 1808-1813

DTIC Science & Technology

2008-05-01

action as an administrator was to prevent the displacement to Madrid of the silver objects of worship from the Church of Notre Dame du Pilar in Saragossa...respect for the Catholic Church , and their aversion for the central power in Madrid . This apparently benevolent action was indeed a skilful information...Insurgencies and Counter-Insurgencies: Guerillas and their Opponents since 1750.London and New York: Routledge, 2001. • Bell , David A. The First Total War.Boston

Naturally Occurring Food Toxins

PubMed Central

Dolan, Laurie C.; Matulka, Ray A.; Burdock, George A.

2010-01-01

Although many foods contain toxins as a naturally-occurring constituent or, are formed as the result of handling or processing, the incidence of adverse reactions to food is relatively low. The low incidence of adverse effects is the result of some pragmatic solutions by the US Food and Drug Administration (FDA) and other regulatory agencies through the creative use of specifications, action levels, tolerances, warning labels and prohibitions. Manufacturers have also played a role by setting limits on certain substances and developing mitigation procedures for process-induced toxins. Regardless of measures taken by regulators and food producers to protect consumers from natural food toxins, consumption of small levels of these materials is unavoidable. Although the risk for toxicity due to consumption of food toxins is fairly low, there is always the possibility of toxicity due to contamination, overconsumption, allergy or an unpredictable idiosyncratic response. The purpose of this review is to provide a toxicological and regulatory overview of some of the toxins present in some commonly consumed foods, and where possible, discuss the steps that have been taken to reduce consumer exposure, many of which are possible because of the unique process of food regulation in the United States. PMID:22069686

5 CFR 1201.125 - Administrative law judge.

Code of Federal Regulations, 2010 CFR

2010-01-01

... PRACTICES AND PROCEDURES Procedures for Original Jurisdiction Cases Special Counsel Disciplinary Actions § 1201.125 Administrative law judge. (a) An administrative law judge will hear a disciplinary action... complaint seeking disciplinary action against a Federal or District of Columbia government employee for a...

Controlling Attention through Action: Observing Actions Primes Action-Related Stimulus Dimensions

ERIC Educational Resources Information Center

Fagioli, Sabrina; Ferlazzo, Fabio; Hommel, Bernhard

2007-01-01

Previous findings suggest that planning an action "backward-primes" perceptual dimension related to this action: planning a grasp facilitates the processing of visual size information, while planning a reach facilitates the processing of location information. Here we show that dimensional priming of perception through action occurs even in the…

7 CFR 356.4 - Property valued at $10,000 or less; notice of seizure administrative action to obtain forfeiture.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 5 2012-01-01 2012-01-01 false Property valued at $10,000 or less; notice of seizure administrative action to obtain forfeiture. 356.4 Section 356.4 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE FORFEITURE...

78 FR 43091 - Technical Operations Safety Action Program (T-SAP) and Air Traffic Safety Action Program (ATSAP)

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-19

... Administration 14 CFR Part 193 [Docket No.: FAA-2013-0375] Technical Operations Safety Action Program (T-SAP) and Air Traffic Safety Action Program (ATSAP) AGENCY: Federal Aviation Administration (FAA), Department of Transportation (DOT). ACTION: Notice of Proposed Order Designating Safety Information as Protected from...

5 CFR 532.413 - Simultaneous action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Simultaneous action. 532.413 Section 532.413 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PREVAILING RATE SYSTEMS Pay Administration § 532.413 Simultaneous action. (a) If an employee becomes entitled to more than...

46 CFR 327.8 - Court action.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 8 2010-10-01 2010-10-01 false Court action. 327.8 Section 327.8 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY SEAMEN'S CLAIMS; ADMINISTRATIVE ACTION AND LITIGATION § 327.8 Court action. No seamen, having a claim specified in subsections (2) and (3) of...

46 CFR 327.8 - Court action.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 8 2011-10-01 2011-10-01 false Court action. 327.8 Section 327.8 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION A-NATIONAL SHIPPING AUTHORITY SEAMEN'S CLAIMS; ADMINISTRATIVE ACTION AND LITIGATION § 327.8 Court action. No seamen, having a claim specified in subsections (2) and (3) of...

45 CFR 77.4 - Remedial actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Remedial actions. 77.4 Section 77.4 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION REMEDIAL ACTIONS APPLICABLE TO LETTER OF CREDIT ADMINISTRATION § 77.4 Remedial actions. If, after the conclusion of the procedures set forth in...

45 CFR 77.4 - Remedial actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Remedial actions. 77.4 Section 77.4 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION REMEDIAL ACTIONS APPLICABLE TO LETTER OF CREDIT ADMINISTRATION § 77.4 Remedial actions. If, after the conclusion of the procedures set forth in...

14 CFR 1275.106 - Administrative actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275... that an institutional official other than those guilty of research misconduct certify the accuracy of... institution to ensure that steps have been taken to prevent repetition of the research misconduct. (3) Group...

14 CFR 1275.106 - Administrative actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275... that an institutional official other than those guilty of research misconduct certify the accuracy of... institution to ensure that steps have been taken to prevent repetition of the research misconduct. (3) Group...

14 CFR 1275.106 - Administrative actions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275... that an institutional official other than those guilty of research misconduct certify the accuracy of... institution to ensure that steps have been taken to prevent repetition of the research misconduct. (3) Group...

14 CFR 1275.106 - Administrative actions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT § 1275... that an institutional official other than those guilty of research misconduct certify the accuracy of... institution to ensure that steps have been taken to prevent repetition of the research misconduct. (3) Group...

29 CFR 15.6 - Administrative action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Solicitor in a timely manner. The Administrative Report shall be in the form of a single memorandum in narrative form with attachments. It should contain all of the following elements, unless permission is... suit. (d) Litigation. During the course of any litigation, organizational units are responsible for...

Cardioprotective Action of Ginkgo biloba Extract against Sustained β-Adrenergic Stimulation Occurs via Activation of M2/NO Pathway.

PubMed

Mesquita, Thássio R R; de Jesus, Itamar C G; Dos Santos, Jucilene F; de Almeida, Grace K M; de Vasconcelos, Carla M L; Guatimosim, Silvia; Macedo, Fabrício N; Dos Santos, Robervan V; de Menezes-Filho, José E R; Miguel-Dos-Santos, Rodrigo; Matos, Paulo T D; Scalzo, Sérgio; Santana-Filho, Valter J; Albuquerque-Júnior, Ricardo L C; Pereira-Filho, Rose N; Lauton-Santos, Sandra

2017-01-01

Ginkgo biloba is the most popular phytotherapic agent used worldwide for treatment of several human disorders. However, the mechanisms involved in the protective actions of Ginkgo biloba on cardiovascular diseases remain poorly elucidated. Taking into account recent studies showing beneficial actions of cholinergic signaling in the heart and the cholinergic hypothesis of Ginkgo biloba -mediated neuroprotection, we aimed to investigate whether Ginkgo biloba extract (GBE) promotes cardioprotection via activation of cholinergic signaling in a model of isoproterenol-induced cardiac hypertrophy. Here, we show that GBE treatment (100 mg/kg/day for 8 days, v.o.) reestablished the autonomic imbalance and baroreflex dysfunction caused by chronic β-adrenergic receptor stimulation (β-AR, 4.5 mg/kg/day for 8 days, i.p.). Moreover, GBE prevented the upregulation of muscarinic receptors (M 2 ) and downregulation of β 1 -AR in isoproterenol treated-hearts. Additionally, we demonstrated that GBE prevents the impaired endothelial nitric oxide synthase activity in the heart. GBE also prevented the pathological cardiac remodeling, electrocardiographic changes and impaired left ventricular contractility that are typical of cardiac hypertrophy. To further investigate the mechanisms involved in GBE cardioprotection in vivo , we performed in vitro studies. By using neonatal cardiomyocyte culture we demonstrated that the antihypertrophic action of GBE was fully abolished by muscarinic receptor antagonist or NOS inhibition. Altogether, our data support the notion that antihypertrophic effect of GBE occurs via activation of M 2 /NO pathway uncovering a new mechanism involved in the cardioprotective action of Ginkgo biloba .

77 FR 42360 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-18

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on... Safety Administration (PHMSA), DOT. ACTION: Notice of actions on Special Permit Applications. SUMMARY: In... given of the actions on special permits applications in (June to June 2012). The mode of transportation...

A strong protective action of guttiferone-A, a naturally occurring prenylated benzophenone, against iron-induced neuronal cell damage.

PubMed

Figueredo, Yanier Núñez; García-Pupo, Laura; Cuesta Rubio, Osmany; Delgado Hernández, René; Naal, Zeki; Curti, Carlos; Pardo Andreu, Gilberto L

2011-01-01

Guttiferone-A (GA) is a natural occurring polyisoprenylated benzophenone with several reported pharmacological actions. We have assessed the protective action of GA on iron-induced neuronal cell damage by employing the PC12 cell line and primary culture of rat cortical neurons (PCRCN). A strong protection by GA, assessed by the 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carbox-anilide (XTT) assay, was revealed, with IC(50) values <1 µM. GA also inhibited Fe(3+)-ascorbate reduction, iron-induced oxidative degradation of 2-deoxiribose, and iron-induced lipid peroxidation in rat brain homogenate, as well as stimulated oxygen consumption by Fe(2+) autoxidation. Absorption spectra and cyclic voltammograms of GA-Fe(2+)/Fe(3+) complexes suggest the formation of a transient charge transfer complex between Fe(2+) and GA, accelerating Fe(2+) oxidation. The more stable Fe(3+) complex with GA would be unable to participate in Fenton-Haber Weiss-type reactions and the propagation phase of lipid peroxidation. The results show a potential of GA against neuronal diseases associated with iron-induced oxidative stress.

7 CFR 356.4 - Property valued at $10,000 or less; notice of seizure administrative action to obtain forfeiture.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 5 2010-01-01 2010-01-01 false Property valued at $10,000 or less; notice of seizure... PROCEDURES § 356.4 Property valued at $10,000 or less; notice of seizure administrative action to obtain... notice of seizure and proposed forfeiture as provided in paragraph (c)(1) of this section, by posting for...

A multiscale approach to modelling electrochemical processes occurring across the cell membrane with application to transmission of action potentials.

PubMed

Richardson, G

2009-09-01

By application of matched asymptotic expansions, a simplified partial differential equation (PDE) model for the dynamic electrochemical processes occurring in the vicinity of a membrane, as ions selectively permeate across it, is formally derived from the Poisson-Nernst-Planck equations of electrochemistry. It is demonstrated that this simplified model reduces itself, in the limit of a long thin axon, to the cable equation used by Hodgkin and Huxley to describe the propagation of action potentials in the unmyelinated squid giant axon. The asymptotic reduction from the simplified PDE model to the cable equation leads to insights that are not otherwise apparent; these include an explanation of why the squid giant axon attains a diameter in the region of 1 mm. The simplified PDE model has more general application than the Hodgkin-Huxley cable equation and can, e.g. be used to describe action potential propagation in myelinated axons and neuronal cell bodies.

78 FR 9771 - Federal Highway Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-11

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Notice of Final Federal Agency Action on Proposed Transportation Project in Illinois and Indiana AGENCY: Federal Highway Administration...., Acting Division Administrator, Federal Highway Administration, 3250 Executive Park Drive, Springfield...

Cardioprotective Action of Ginkgo biloba Extract against Sustained β-Adrenergic Stimulation Occurs via Activation of M2/NO Pathway

PubMed Central

Mesquita, Thássio R. R.; de Jesus, Itamar C. G.; dos Santos, Jucilene F.; de Almeida, Grace K. M.; de Vasconcelos, Carla M. L.; Guatimosim, Silvia; Macedo, Fabrício N.; dos Santos, Robervan V.; de Menezes-Filho, José E. R.; Miguel-dos-Santos, Rodrigo; Matos, Paulo T. D.; Scalzo, Sérgio; Santana-Filho, Valter J.; Albuquerque-Júnior, Ricardo L. C.; Pereira-Filho, Rose N.; Lauton-Santos, Sandra

2017-01-01

Ginkgo biloba is the most popular phytotherapic agent used worldwide for treatment of several human disorders. However, the mechanisms involved in the protective actions of Ginkgo biloba on cardiovascular diseases remain poorly elucidated. Taking into account recent studies showing beneficial actions of cholinergic signaling in the heart and the cholinergic hypothesis of Ginkgo biloba-mediated neuroprotection, we aimed to investigate whether Ginkgo biloba extract (GBE) promotes cardioprotection via activation of cholinergic signaling in a model of isoproterenol-induced cardiac hypertrophy. Here, we show that GBE treatment (100 mg/kg/day for 8 days, v.o.) reestablished the autonomic imbalance and baroreflex dysfunction caused by chronic β-adrenergic receptor stimulation (β-AR, 4.5 mg/kg/day for 8 days, i.p.). Moreover, GBE prevented the upregulation of muscarinic receptors (M2) and downregulation of β1-AR in isoproterenol treated-hearts. Additionally, we demonstrated that GBE prevents the impaired endothelial nitric oxide synthase activity in the heart. GBE also prevented the pathological cardiac remodeling, electrocardiographic changes and impaired left ventricular contractility that are typical of cardiac hypertrophy. To further investigate the mechanisms involved in GBE cardioprotection in vivo, we performed in vitro studies. By using neonatal cardiomyocyte culture we demonstrated that the antihypertrophic action of GBE was fully abolished by muscarinic receptor antagonist or NOS inhibition. Altogether, our data support the notion that antihypertrophic effect of GBE occurs via activation of M2/NO pathway uncovering a new mechanism involved in the cardioprotective action of Ginkgo biloba. PMID:28553225

49 CFR 27.11 - Remedial action, voluntary action and compliance planning.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 1 2011-10-01 2011-10-01 false Remedial action, voluntary action and compliance....11 Remedial action, voluntary action and compliance planning. (a) Remedial action. (1) If the... discrimination not occurred. (b) Voluntary action. A recipient may take steps, in addition to any action that is...

Psychologists in Academic Administration: A Call to Action and Service.

PubMed

Schmaling, Karen B; Linton, John C

2017-06-01

Academic psychologists' backgrounds may prepare them for many aspects of academic administration such as: understanding and working with people; prioritizing others' needs and institutional needs; and managing projects and budgets, e.g., for research grants or training programs. Contemporary academic health centers also may provide opportunities for psychologists to serve in academic health administration. This article encourages psychologists to consider preparing for and seeking administrative and higher-level leadership roles. Six psychologists serving diverse administrative roles-from vice chairs in medical school departments to presidents of universities with academic health centers-reflected on: their paths to administration; their preparation for administrative roles; and the commonalities and differences between the work and skills sets of psychologist health service providers and the work and skill sets required for higher level administrative and leadership roles.

45 CFR 77.5 - Remedial action procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Remedial action procedures. 77.5 Section 77.5 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION REMEDIAL ACTIONS APPLICABLE TO LETTER OF CREDIT ADMINISTRATION § 77.5 Remedial action procedures. Except as provided in § 77.6...

76 FR 34120 - Action Subject to Intergovernmental Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-10

... SMALL BUSINESS ADMINISTRATION Action Subject to Intergovernmental Review AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: Under Executive Order 12372, the Small Business Administration (SBA) is notifying the public that it intends to grant the pending applications of 39 existing...

76 FR 34119 - Action Subject to Intergovernmental Review

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-10

... SMALL BUSINESS ADMINISTRATION Action Subject to Intergovernmental Review AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: Under Executive Order 12372, the Small Business Administration (SBA) is notifying the public that it intends to grant the pending applications of 22 existing...

48 CFR 342.7101 - Contract administration.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Contract administration. 342.7101 Section 342.7101 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES CONTRACT MANAGEMENT CONTRACT ADMINISTRATION Administrative Actions for Cost Overruns 342.7101 Contract administration. ...

48 CFR 342.7101 - Contract administration.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Contract administration. 342.7101 Section 342.7101 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES CONTRACT MANAGEMENT CONTRACT ADMINISTRATION Administrative Actions for Cost Overruns 342.7101 Contract administration. ...

28 CFR 544.44 - Disciplinary action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Disciplinary action. 544.44 Section 544.44 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT EDUCATION Mandatory English-as-a-Second Language Program (ESL) § 544.44 Disciplinary action. As with any...

28 CFR 544.44 - Disciplinary action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Disciplinary action. 544.44 Section 544.44 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT EDUCATION Mandatory English-as-a-Second Language Program (ESL) § 544.44 Disciplinary action. As with any...

28 CFR 544.75 - Disciplinary action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Disciplinary action. 544.75 Section 544.75 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT EDUCATION Literacy Program § 544.75 Disciplinary action. As with other mandatory programs, such as work...

Balancing RIF & Affirmative Action: A Guidebook for Administrators. Draft.

ERIC Educational Resources Information Center

Ruzicka, Pat; Berard, Barbara, Ed.

The result of two seminars bringing together educators to discuss the "often conflicting requirements of affirmative action and reductions in force" (RIF), this booklet is intended to provide practical insights and suggestions on meeting affirmative action goals "in situations characterized by staff and program cutbacks." Chapter 1 describes…

22 CFR 223.11 - Appropriate action.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Appropriate action. 223.11 Section 223.11...-EMPLOYMENT RESTRICTIONS § 223.11 Appropriate action. The Administrator may take appropriate action in the... action. ...

22 CFR 223.11 - Appropriate action.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Appropriate action. 223.11 Section 223.11...-EMPLOYMENT RESTRICTIONS § 223.11 Appropriate action. The Administrator may take appropriate action in the... action. ...

15 CFR 766.25 - Administrative action denying export privileges.

Code of Federal Regulations, 2013 CFR

2013-01-01

... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

15 CFR 766.25 - Administrative action denying export privileges.

Code of Federal Regulations, 2012 CFR

2012-01-01

... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

15 CFR 766.25 - Administrative action denying export privileges.

Code of Federal Regulations, 2010 CFR

2010-01-01

... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

15 CFR 766.25 - Administrative action denying export privileges.

Code of Federal Regulations, 2011 CFR

2011-01-01

... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

15 CFR 766.25 - Administrative action denying export privileges.

Code of Federal Regulations, 2014 CFR

2014-01-01

... of a violation of the EAA, the EAR, or any order, license, or authorization issued thereunder; any... transaction subject to the EAR. Before taking action to deny a person export privileges under this section... privileges” for purposes of § 736.2(b)(4) (General Prohibition 4—Engage in actions prohibited by a denial...

28 CFR 115.404 - Audit corrective action plan.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Audit corrective action plan. 115.404 Section 115.404 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Auditing and Corrective Action § 115.404 Audit corrective action plan. (a) A finding of...

28 CFR 115.404 - Audit corrective action plan.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Audit corrective action plan. 115.404 Section 115.404 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Auditing and Corrective Action § 115.404 Audit corrective action plan. (a) A finding of...

28 CFR 115.404 - Audit corrective action plan.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Audit corrective action plan. 115.404 Section 115.404 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PRISON RAPE ELIMINATION ACT NATIONAL STANDARDS Auditing and Corrective Action § 115.404 Audit corrective action plan. (a) A finding of...

28 CFR 902.7 - Court action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Court action. 902.7 Section 902.7 Judicial Administration NATIONAL CRIME PREVENTION AND PRIVACY COMPACT COUNCIL DISPUTE ADJUDICATION PROCEDURES § 902.7 Court action. Pursuant to Section (c) of Article XI of the Compact, a decision by the...

Response to Agencywide Crisis: A Model for Administrative Action.

ERIC Educational Resources Information Center

Alwon, Floyd J.

1980-01-01

Guidelines are suggested whereby mental health agency administrators can promote organizational growth and avoid dangers during an agency crisis. Emphasis is placed on the administrator's comprehension of leadership styles and task organization. Typical staff reactions to agency crises are described. (Author/DB)

50 CFR 11.24 - Final administrative action.

Code of Federal Regulations, 2010 CFR

2010-10-01

... TAKING, POSSESSION, TRANSPORTATION, SALE, PURCHASE, BARTER, EXPORTATION, AND IMPORTATION OF WILDLIFE AND... law judge's decision shall constitute the final administrative determination of the Secretary in the matter and shall become effective 30 calendar days from the date of the decision. ...

42 CFR 93.523 - The Administrative Law Judge's ruling.

Code of Federal Regulations, 2010 CFR

2010-10-01

... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.523 The Administrative Law Judge's ruling. (a) The ALJ shall issue a... decision in whole or in part is the final HHS action, unless debarment or suspension is an administrative...

42 CFR 93.523 - The Administrative Law Judge's ruling.

Code of Federal Regulations, 2011 CFR

2011-10-01

... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.523 The Administrative Law Judge's ruling. (a) The ALJ shall issue a... decision in whole or in part is the final HHS action, unless debarment or suspension is an administrative...

75 FR 6433 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-09

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Availability of a Draft... 9, West Chicago, IL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of... Surveillance Radar, Model 9, West Chicago, Illinois. SUMMARY: The Federal Aviation Administration (FAA...

75 FR 18014 - Federal Highway Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-08

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of Availability regarding a Finding of No Significant Impact (FONSI): U.S.... FOR FURTHER INFORMATION CONTACT: Federal Highway Administration, Kentucky Division: Mr. Greg Rawlings...

76 FR 78966 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-20

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Approval of Noise Compatibility Program for Kona International Airport at Keahole, Keahole, North Kona, HI AGENCY: Federal Aviation Administration, DOT. ACTION: Notice. SUMMARY: The Federal Aviation Administration (FAA) announces its findings on...

75 FR 12809 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-17

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Intent To Rule on Request...: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Request to Release Airport Property. SUMMARY... Nicely, Manager, Federal Aviation Administration, Southwest Region, Airports Division, Texas Airports...

The gender differences in the inhibitory action of UVB-induced melanocyte activation by the administration of tranexamic acid.

PubMed

Hiramoto, Keiichi; Yamate, Yurika; Sugiyama, Daijiro; Takahashi, Yumi; Mafune, Eiichi

2016-05-01

Tranexamic acid has an inhibitory action on ultraviolet (UV) B-induced melanocyte activation. This study examined the sex differences in the inhibitory action of tranexamic acid on UVB-induced melanocyte activation. We irradiated the eye and ear of male and female mice with UVB at a dose of 1.0 kJ/m(2) using a 20SE sunlamp. We orally administered tranexamic acid (750 mg/kg/day) at 30 min before UVB exposure. Tranexamic acid inhibited the UVB-induced epidermal melanocyte activation, and the effect was more remarkable under UVB eye irradiation than under UVB ear irradiation. Furthermore, the melanocyte activity suppression effect was stronger in female mice than in male mice. Following the administration of tranexamic acid, the female displayed increased blood levels of β-endorphin and μ-opioid receptor and estradiol receptor β expression in comparison with the male. Furthermore, the effect of melanocyte activity suppression in the female mice was decreased by the administration of tamoxifen (antagonist of estrogen receptor) or naltrexone (antagonist of μ-opioid receptor). These results suggest that the suppression by tranexamic acid of the UVB-induced melanocyte activation (UVB sensitivity) is stronger in female mice than in male mice and that female hormones and β-endorphin play an important role in this sex difference. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

78 FR 25524 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-01

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Request To Release Airport Property AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of Intent to Rule on Request to... address: Lynn D. Martin, Airports Compliance Specialist, Federal Aviation Administration, Airports...

5 CFR 772.102 - Interim personnel actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Interim personnel actions. 772.102 Section 772.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) INTERIM RELIEF General § 772.102 Interim personnel actions. When an employee or...

5 CFR 772.102 - Interim personnel actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Interim personnel actions. 772.102 Section 772.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) INTERIM RELIEF General § 772.102 Interim personnel actions. When an employee or...

78 FR 13395 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-27

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of Availability of Draft...: Federal Aviation Administration (FAA), DOT. ACTION: Notice of availability and request for comments... 4. U.S. Mail: Leslie Grey--AAL-614, Federal Aviation Administration, Airports Division, 222 West 7th...

78 FR 41183 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-09

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Meeting: RTCA Program Management Committee AGENCY: Federal Aviation Administration (FAA), U.S. Department of Transportation (DOT). ACTION... Operations Group, Federal Aviation Administration. [FR Doc. 2013-16464 Filed 7-8-13; 8:45 am] BILLING CODE...

Ameliorating treatment-refractory depression with intranasal ketamine: potential NMDA receptor actions in the pain circuitry representing mental anguish.

PubMed

Opler, Lewis A; Opler, Mark G A; Arnsten, Amy F T

2016-02-01

This article reviews the antidepressant actions of ketamine, an N-methyl-D-aspartame glutamate receptor (NMDAR) antagonist, and offers a potential neural mechanism for intranasal ketamine's ultra-rapid actions based on the key role of NMDAR in the nonhuman primate prefrontal cortex (PFC). Although intravenous ketamine infusions can lift mood within hours, the current review describes how intranasal ketamine administration can have ultra-rapid antidepressant effects, beginning within minutes (5-40 minutes) and lasting hours, but with repeated treatments needed for sustained antidepressant actions. Research in rodents suggests that increased synaptogenesis in PFC may contribute to the prolonged benefit of ketamine administration, beginning hours after administration. However, these data cannot explain the relief that occurs within minutes of intranasal ketamine delivery. We hypothesize that the ultra-rapid effects of intranasal administration in humans may be due to ketamine blocking the NMDAR circuits that generate the emotional representations of pain (eg, Brodmann Areas 24 and 25, insular cortex), cortical areas that can be overactive in depression and which sit above the nasal epithelium. In contrast, NMDAR blockade in the dorsolateral PFC following systemic administration of ketamine may contribute to cognitive deficits. This novel view may help to explain how intravenous ketamine can treat the symptoms of depression yet worsen the symptoms of schizophrenia.

14 CFR § 1275.106 - Administrative actions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... § 1275.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION RESEARCH MISCONDUCT... that an institutional official other than those guilty of research misconduct certify the accuracy of... institution to ensure that steps have been taken to prevent repetition of the research misconduct. (3) Group...

78 FR 11216 - Enforcement Actions Summary

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-15

...] Enforcement Actions Summary AGENCY: Transportation Security Administration, DHS. ACTION: Notice of... an annual summary of all enforcement actions taken by TSA under the authority granted in the... public with an annual summary of all enforcement actions taken by TSA under this subsection; and include...

77 FR 12865 - Enforcement Actions Summary

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-02

...] Enforcement Actions Summary AGENCY: Transportation Security Administration, DHS. ACTION: Notice of... an annual summary of all enforcement actions taken by TSA under the authority granted in the... public with an annual summary of all enforcement actions taken by TSA under this subsection; and include...

76 FR 9357 - Enforcement Actions Summary

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-17

...] Enforcement Actions Summary AGENCY: Transportation Security Administration, DHS. ACTION: Notice of... an annual summary of all enforcement actions taken by TSA under the authority granted in the... to provide the public with an annual summary of all enforcement actions taken by TSA under this...

40 CFR 265.259 - Response actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... response action plan must set forth the actions to be taken if the action leakage rate has been exceeded... section. (b) If the flow rate into the leak determination system exceeds the action leakage rate for any... notification that the action leakage rate has been exceeded, submit to the Regional Administrator the results...

5 CFR 930.113 - Corrective action.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Corrective action. 930.113 Section 930....113 Corrective action. An agency will take adverse, disciplinary, or other appropriate action against... such action against an operator or an incidental operator: (a) The employee is convicted of operating...

5 CFR 930.113 - Corrective action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Corrective action. 930.113 Section 930....113 Corrective action. An agency will take adverse, disciplinary, or other appropriate action against... such action against an operator or an incidental operator: (a) The employee is convicted of operating...

5 CFR 250.103 - Consequences of improper agency actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Consequences of improper agency actions. 250.103 Section 250.103 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE... Consequences of improper agency actions. If OPM finds that an agency has taken an action contrary to a law...

40 CFR 265.224 - Response actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... action plan. The response action plan must set forth the actions to be taken if the action leakage rate... paragraph (b) of this section. (b) If the flow rate into the leak detection system exceeds the action leakage rate for any sump, the owner or operator must: (1) Notify the Regional Administrator in writing of...

40 CFR 264.223 - Response actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) If the flow rate into the leak detection system exceeds the action leakage rate for any sump, the... action plan must set forth the actions to be taken if the action leakage rate has been exceeded. At a... action leakage rate has been exceeded, submit to the Regional Administrator the results of the analyses...

40 CFR 265.303 - Response actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... section. (b) If the flow rate into the leak detection system exceeds the action leakage rate for any sump... response action plan must set forth the actions to be taken if the action leakage rate has been exceeded... notification that the action leakage rate has been exceeded, submit to the Regional Administrator the results...

5 CFR 1201.125 - Administrative law judge.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Administrative law judge. 1201.125... § 1201.125 Administrative law judge. (a) An administrative law judge will hear a disciplinary action... administrative law judge will issue an initial decision on the complaint pursuant to 5 U.S.C. 557. The applicable...

45 CFR 32.12 - Right of action.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Right of action. 32.12 Section 32.12 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION ADMINISTRATIVE WAGE GARNISHMENT § 32.12 Right of action. (a) The employer of a debtor subject to wage withholding pursuant to this part...

"Progress or Abuse--A Choice." A Study to Investigate the Need for Legislative and Administrative Actions Regarding Standards of Progress Provisions of the GI Bill and Class Session Requirements of the Veterans' Administration Regulations.

ERIC Educational Resources Information Center

Veterans Administration, Washington, DC.

The need for legislative and administrative action was examined in regard to the GI Bill and the satisfactory progress requirements and the "seat-time" requirements prescribed by regulation. Information is presented on the GI Bill Improvement Act of 1977 (P.L. 95-202), standards of progress of the veteran student, and contact time, or…

48 CFR 9901.314 - Informal actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Informal actions. 9901.314... actions. The Chairman may take actions on behalf of the Board on administrative issues, as determined by the Chairman, without holding an official meeting of the members. However, details of the actions so...

48 CFR 9901.314 - Informal actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Informal actions. 9901.314... actions. The Chairman may take actions on behalf of the Board on administrative issues, as determined by the Chairman, without holding an official meeting of the members. However, details of the actions so...

14 CFR 13.19 - Certificate action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Certificate action. 13.19 Section 13.19... INVESTIGATIVE AND ENFORCEMENT PROCEDURES Legal Enforcement Actions § 13.19 Certificate action. (a) Under section... charges or other reasons upon which the Administrator bases the proposed action and, except in an...

77 FR 20779 - Committee on Administration and Management

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-06

... Committee on Administration and Management AGENCY: Administrative Conference of the United States. ACTION... Administration and Management of the Assembly of the Administrative Conference of the United States. The meeting... Committees,'' and then on ``Committee on Administration and Management.'' Comments may be submitted by email...

46 CFR 5.19 - Administrative Law Judge.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 46 Shipping 1 2014-10-01 2014-10-01 false Administrative Law Judge. 5.19 Section 5.19 Shipping... REGULATIONS-PERSONNEL ACTION Definitions § 5.19 Administrative Law Judge. (a) An Administrative Law Judge... has delegated to Administrative Law Judges the authority to admonish, suspend, with or without...

46 CFR 5.19 - Administrative Law Judge.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 46 Shipping 1 2012-10-01 2012-10-01 false Administrative Law Judge. 5.19 Section 5.19 Shipping... REGULATIONS-PERSONNEL ACTION Definitions § 5.19 Administrative Law Judge. (a) An Administrative Law Judge... has delegated to Administrative Law Judges the authority to admonish, suspend, with or without...

46 CFR 5.19 - Administrative Law Judge.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 46 Shipping 1 2013-10-01 2013-10-01 false Administrative Law Judge. 5.19 Section 5.19 Shipping... REGULATIONS-PERSONNEL ACTION Definitions § 5.19 Administrative Law Judge. (a) An Administrative Law Judge... has delegated to Administrative Law Judges the authority to admonish, suspend, with or without...

46 CFR 5.19 - Administrative Law Judge.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 1 2011-10-01 2011-10-01 false Administrative Law Judge. 5.19 Section 5.19 Shipping... REGULATIONS-PERSONNEL ACTION Definitions § 5.19 Administrative Law Judge. (a) An Administrative Law Judge... has delegated to Administrative Law Judges the authority to admonish, suspend, with or without...

29 CFR 1625.30 - Administrative exemptions; procedures.

Code of Federal Regulations, 2013 CFR

2013-07-01

....30 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.30 Administrative exemptions; procedures. (a... discrimination in employment. Administrative action consistent with this statutory purpose may be taken under...

29 CFR 1625.30 - Administrative exemptions; procedures.

Code of Federal Regulations, 2012 CFR

2012-07-01

....30 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.30 Administrative exemptions; procedures. (a... discrimination in employment. Administrative action consistent with this statutory purpose may be taken under...

29 CFR 1625.30 - Administrative exemptions; procedures.

Code of Federal Regulations, 2011 CFR

2011-07-01

....30 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.30 Administrative exemptions; procedures. (a... discrimination in employment. Administrative action consistent with this statutory purpose may be taken under...

29 CFR 1625.30 - Administrative exemptions; procedures.

Code of Federal Regulations, 2014 CFR

2014-07-01

....30 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.30 Administrative exemptions; procedures. (a... discrimination in employment. Administrative action consistent with this statutory purpose may be taken under...

29 CFR 1625.30 - Administrative exemptions; procedures.

Code of Federal Regulations, 2010 CFR

2010-07-01

....30 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION AGE DISCRIMINATION IN EMPLOYMENT ACT Administrative Exemptions § 1625.30 Administrative exemptions; procedures. (a... discrimination in employment. Administrative action consistent with this statutory purpose may be taken under...

Noble or Malevolent in a Moment of Dismay: How Postsecondary Students Construe and Characterize Bystander Action in School Violence Shooting Incidents

ERIC Educational Resources Information Center

Underhill, Dyan Whitlow

2012-01-01

Multiple incidents of postsecondary school shooting violence have occurred in American society--prompting concern about safety on college campuses, administrators' roles in prevention, and proactive and responsible bystander actions. Active shooter plans have become more established in educational environments, with efforts are directed…

78 FR 25337 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-30

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Agency Information Collection Activities: Requests for Comments; Clearance of Renewed Approval of Information Collection: Operations Specifications AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice and request for comments...

14 CFR 13.19 - Certificate action.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Certificate action. 13.19 Section 13.19... INVESTIGATIVE AND ENFORCEMENT PROCEDURES Legal Enforcement Actions § 13.19 Certificate action. (a) Under section... Administrator bases the proposed action and, except in an emergency, allows the holder to answer any charges and...

76 FR 45621 - Employment and Training Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-29

... DEPARTMENT OF LABOR Employment and Training Administration Comment Request for Extension of... Administration. ACTION: Notice. SUMMARY: The Department of Labor (Department), as part of its continuing effort..., the Employment and Training Administration (ETA) is soliciting comments concerning the extension of...

AMELIORATING TREATMENT-REFRACTORY DEPRESSION WITH INTRANASAL KETAMINE: POTENTIAL NMDA RECEPTOR ACTIONS IN THE PAIN CIRCUITRY REPRESENTING MENTAL ANGUISH

PubMed Central

Opler, Lewis A.; Opler, Mark G.; Arnsten, Amy F.T.

2014-01-01

This paper reviews the anti-depressant actions of the N-methyl-D-aspartame glutamate receptor (NMDAR) antagonist, ketamine, and offers a potential neural mechanism for intranasal ketamine’s ultra-rapid actions based on the key role of NMDAR in the nonhuman primate prefrontal cortex (PFC). Although intravenous ketamine infusions can lift mood within hours, the current review describes how intranasal ketamine administration can have ultra-rapid antidepressant effects, beginning within minutes (5–40 minutes) and lasting hours, but with repeated treatments needed for sustained antidepressant actions. Research in rodents suggests that increased synaptogenesis in PFC may contribute to the prolonged benefit of ketamine administration, beginning hours after administration. However, these data cannot explain the relief that occurs within minutes of intranasal ketamine delivery. We hypothesize that the ultra-rapid effects of intranasal administration in humans may be due to ketamine blocking the NMDAR circuits that generate the emotional representations of pain (e.g. Brodmann Areas 24 and 25, insular cortex), cortical areas that can be overactive in depression and which sit above the nasal epithelium. In contrast, NMDAR blockade in the dorsolateral PFC following systemic administration of ketamine may contribute to cognitive deficits. This novel view may help to explain how intravenous ketamine can treat the symptoms of depression yet worsen the symptoms of schizophrenia. PMID:25619798

49 CFR 386.54 - Administrative Law Judge.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 5 2011-10-01 2011-10-01 false Administrative Law Judge. 386.54 Section 386.54... General Rules and Hearings § 386.54 Administrative Law Judge. (a) Powers of an Administrative Law Judge. The Administrative Law Judge may take any action and may prescribe all necessary rules and regulations...

49 CFR 386.54 - Administrative Law Judge.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 5 2013-10-01 2013-10-01 false Administrative Law Judge. 386.54 Section 386.54... General Rules and Hearings § 386.54 Administrative Law Judge. (a) Powers of an Administrative Law Judge. The Administrative Law Judge may take any action and may prescribe all necessary rules and regulations...

49 CFR 386.54 - Administrative Law Judge.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 5 2010-10-01 2010-10-01 false Administrative Law Judge. 386.54 Section 386.54... General Rules and Hearings § 386.54 Administrative Law Judge. (a) Powers of an Administrative Law Judge. The Administrative Law Judge may take any action and may prescribe all necessary rules and regulations...

78 FR 18420 - Special Permit Applications Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-26

... Applications Actions AGENCY: Pipeline and Hazardous Materials Safety Administration (PHMSA), DOT. ACTION: Notice of actions on special permit applications. SUMMARY: In accordance with the procedures governing... Hazardous Material Regulations (49 CFR part 107, subpart B), notice is hereby given of the actions on...

75 FR 57820 - National Credit Union Administration Restoration Plan

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-22

... NATIONAL CREDIT UNION ADMINISTRATION National Credit Union Administration Restoration Plan AGENCY: National Credit Union Administration (NCUA). ACTION: Approval of National Credit Union Administration restoration plan. On September 16, 2010, the National Credit Union Administration (NCUA) implemented a...

41 CFR 105-57.012 - Actions prohibited by the employer.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Administration 57-ADMINISTRATION WAGE GARNISHMENT § 105-57.012 Actions prohibited by the employer. An employer may not discharge, refuse to employ, or take disciplinary action against the debtor due to the... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Actions prohibited by...

20 CFR 416.1402 - Administrative actions that are initial determinations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... determinations. 416.1402 Section 416.1402 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Determinations, Administrative Review Process, and... preponderance of the evidence. We will state the important facts and give the reasons for our conclusions in the...

20 CFR 658.702 - Initial action by the Regional Administrator.

Code of Federal Regulations, 2010 CFR

2010-04-01

... JS regulations. (b) Wherever a Regional Administrator discovers or is apprised of possible State agency violations of JS regulations by the review and assessment activities under subpart G of this part... a State agency has violated JS regulations. (c) The Regional Administrator shall accept complaints...

Women as Academic Administrators in the Age of Affirmative Action.

ERIC Educational Resources Information Center

Palley, Marian Lief

1978-01-01

Data indicate that, once academic women select or are selected for administrative careers, quantitative opportunities are available to those who seem to be approximately equivalent to men. However, if qualitative measures are assessed, it becomes clear that women administrators do not fare as well as men. (Author)

5 CFR 315.909 - Relationship to other actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Relationship to other actions. 315.909 Section 315.909 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS CAREER... Position § 315.909 Relationship to other actions. (a) If an employee is required to concurrently serve both...

38 CFR 18.550 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... administrative remedies. 18.550 Section 18.550 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS..., Conciliation, and Enforcement Procedures § 18.550 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act. Administrative...

47 CFR 1.1906 - Informal action.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 1 2011-10-01 2011-10-01 false Informal action. 1.1906 Section 1.1906... United States General Provisions § 1.1906 Informal action. Nothing contained in these regulations is intended to preclude utilization of informal administrative actions or remedies which may be available...

47 CFR 1.1906 - Informal action.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Informal action. 1.1906 Section 1.1906... United States General Provisions § 1.1906 Informal action. Nothing contained in these regulations is intended to preclude utilization of informal administrative actions or remedies which may be available...

23 CFR 771.137 - International actions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false International actions. 771.137 Section 771.137 Highways... IMPACT AND RELATED PROCEDURES § 771.137 International actions. (a) The requirements of this part apply to: (1) Administration actions significantly affecting the environment of a foreign nation not...

Administrative Leadership as Projection, Social Control, and Action.

ERIC Educational Resources Information Center

Reed, Donald B.

Over the past 50 years, theoretical and methodological problems have plagued the study of leadership. This paper, proposing an alternative theory, argues that leadership has three fundamental components: projection and social control, which are linked by action. Projection is the visualization of a project to be completed. Educational…

76 FR 2745 - Federal Aviation Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-14

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Eighty-Fourth Meeting: RTCA Special Committee 159: Global Positioning System (GPS) AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of RTCA Special Committee 159 meeting: Global Positioning System (GPS). SUMMARY: The FAA is...

20 CFR 410.610 - Administrative actions that are initial determinations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... determinations. 410.610 Section 410.610 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE...) Withdrawal of claim or cancellation of withdrawal request. When a request for withdrawal of a claim, or a request for cancellation of a “request for withdrawal” of a claim, is denied by the Administration, the...

18 CFR 401.89 - Action by the Commission.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Action by the Commission. 401.89 Section 401.89 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Administrative and Other Hearings § 401.89 Action by the...

ELECTROCARDIOGRAPHIC CHANGES IN RABBITS SUBJECTED TO THE CHRONIC ACTION OF RADIOACTIVE ZINC DURING INTRAVENOUS ADMINISTRATION OF ADRENALINE AND INHALATION OF AMMONIA (in Russian)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ovakimov, V.G.; Bibikhin, L.N.; Saitanov, A.O.

1963-09-01

The employment of pharmacological loadings (administration of adrenaline and inhalation of ammonia) in rabbits subjected to the chronic action of radioactive zinc (1 and 10 mu C/kg) disclosed changes in the sensitivity of adrenoreactive systems of the myocardium (in adrenaline test) and an altered intensity and duration of reflex bradycardia (in ammonia test). (auth)

21 CFR 1309.41 - Administrative review generally.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

21 CFR 1309.41 - Administrative review generally.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

21 CFR 1309.41 - Administrative review generally.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

21 CFR 1309.41 - Administrative review generally.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

21 CFR 1309.41 - Administrative review generally.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Administrative review generally. 1309.41 Section... MANUFACTURERS, DISTRIBUTORS, IMPORTERS AND EXPORTERS OF LIST I CHEMICALS Action on Applications for Registration: Revocation Or Suspension of Registration § 1309.41 Administrative review generally. The Administrator may...

40 CFR 77.4 - Administrator's action on proposed offset plans.

Code of Federal Regulations, 2012 CFR

2012-07-01

... representative. The Administrator will also give notice of any approval in the Federal Register. The plans will... response to public comments submitted on the draft offset plan or disapproval of a draft offset plan... offset plan. The Administrator will serve a copy of any approved offset plan and the response to comments...

40 CFR 77.4 - Administrator's action on proposed offset plans.

Code of Federal Regulations, 2014 CFR

2014-07-01

... representative. The Administrator will also give notice of any approval in the Federal Register. The plans will... response to public comments submitted on the draft offset plan or disapproval of a draft offset plan... offset plan. The Administrator will serve a copy of any approved offset plan and the response to comments...

40 CFR 77.4 - Administrator's action on proposed offset plans.

Code of Federal Regulations, 2010 CFR

2010-07-01

... representative. The Administrator will also give notice of any approval in the Federal Register. The plans will... response to public comments submitted on the draft offset plan or disapproval of a draft offset plan... offset plan. The Administrator will serve a copy of any approved offset plan and the response to comments...

40 CFR 77.4 - Administrator's action on proposed offset plans.

Code of Federal Regulations, 2011 CFR

2011-07-01

... representative. The Administrator will also give notice of any approval in the Federal Register. The plans will... response to public comments submitted on the draft offset plan or disapproval of a draft offset plan... offset plan. The Administrator will serve a copy of any approved offset plan and the response to comments...

28 CFR 544.75 - Disciplinary action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Disciplinary action. 544.75 Section 544... EDUCATION Literacy Program § 544.75 Disciplinary action. As with other mandatory programs, such as work assignments, staff may take disciplinary action against an inmate lacking a GED credential or high school...

29 CFR 1450.6 - Informal action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false Informal action. 1450.6 Section 1450.6 Labor Regulations... UNITED STATES General Provisions § 1450.6 Informal action. Nothing contained in this regulation is intended to preclude utilization of informal administrative actions or remedies which may be available. ...

5 CFR 250.103 - Consequences of improper agency actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Consequences of improper agency actions. 250.103 Section 250.103 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERSONNEL MANAGEMENT IN AGENCIES Authority for Personnel Actions in Agencies § 250.103...

5 CFR 731.105 - Authority to take suitability actions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Authority to take suitability actions. 731.105 Section 731.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.105 Authority to take suitability actions. (a...

5 CFR 731.105 - Authority to take suitability actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Authority to take suitability actions. 731.105 Section 731.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.105 Authority to take suitability actions. (a...

5 CFR 731.105 - Authority to take suitability actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Authority to take suitability actions. 731.105 Section 731.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.105 Authority to take suitability actions. (a...

5 CFR 731.105 - Authority to take suitability actions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Authority to take suitability actions. 731.105 Section 731.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.105 Authority to take suitability actions. (a...

5 CFR 731.105 - Authority to take suitability actions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Authority to take suitability actions. 731.105 Section 731.105 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) SUITABILITY Scope § 731.105 Authority to take suitability actions. (a...

75 FR 60768 - Single-Ingredient Oral Colchicine Products; Enforcement Action Dates

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-01

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0257] Single-Ingredient Oral Colchicine Products; Enforcement Action Dates AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA or agency) is announcing its...

75 FR 34960 - Import Administration IA ACCESS Pilot Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-21

... DEPARTMENT OF COMMERCE International Trade Administration 19 CFR Part 351 [Docket No. 100602237-0250-02] Import Administration IA ACCESS Pilot Program AGENCY: Import Administration, International Trade Administration, Department of Commerce. ACTION: Public notice and request for comments; correction...

75 FR 37877 - Federal Highway Administration (FHWA), DOT.

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-30

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Buy America Waiver Notification Federal Highway Administration (FHWA), DOT. ACTION: Notice. SUMMARY: This notice provides information... Program Administration, (202) 366-1562, or via e-mail at [email protected] . For legal questions...

29 CFR 35.40 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true Exhaustion of administrative remedies. 35.40 Section 35.40... Enforcement Procedures § 35.40 Exhaustion of administrative remedies. (a) A complainant may file a civil action under the Act following the exhaustion of administrative remedies. Administrative remedies are...

34 CFR 110.39 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Exhaustion of administrative remedies. 110.39 Section... administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act. Administrative remedies are exhausted if— (1) One hundred eighty days have elapsed...

29 CFR 35.40 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 1 2011-07-01 2011-07-01 false Exhaustion of administrative remedies. 35.40 Section 35.40... Enforcement Procedures § 35.40 Exhaustion of administrative remedies. (a) A complainant may file a civil action under the Act following the exhaustion of administrative remedies. Administrative remedies are...

48 CFR 9901.310 - Board action.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Board action. 9901.310... PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATION RULES AND PROCEDURES 9901.310 Board action. Board action shall be by majority vote of the members present and voting, except that any vote to...

48 CFR 9901.310 - Board action.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Board action. 9901.310... PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATION RULES AND PROCEDURES 9901.310 Board action. Board action shall be by majority vote of the members present and voting, except that any vote to...

77 FR 58213 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-19

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on.... ACTION: Notice of actions on Special Permit Applications. SUMMARY: In accordance with the procedures... actions on special permits applications in (August to August 2012). The mode of transportation involved...

32 CFR 1602.2 - Administrative classification.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Administrative classification. 1602.2 Section 1602.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.2 Administrative classification. A reclassification action relating to a registrant's claim...

32 CFR 1602.2 - Administrative classification.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Administrative classification. 1602.2 Section 1602.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.2 Administrative classification. A reclassification action relating to a registrant's claim...

32 CFR 1602.2 - Administrative classification.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Administrative classification. 1602.2 Section 1602.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.2 Administrative classification. A reclassification action relating to a registrant's claim...

32 CFR 1602.2 - Administrative classification.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Administrative classification. 1602.2 Section 1602.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.2 Administrative classification. A reclassification action relating to a registrant's claim...

32 CFR 1602.2 - Administrative classification.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Administrative classification. 1602.2 Section 1602.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM DEFINITIONS § 1602.2 Administrative classification. A reclassification action relating to a registrant's claim...

Caloric restriction and IGF-I administration promote rabbit fecundity: Possible interrelationships and mechanisms of action.

PubMed

Sirotkin, Alexander V; Florkovičová, Iveta Koničková; Švarcová, Olga Østrup; Rafay, Jan; Laurincik, Jozef; Harrath, Abdel Halim

2017-03-01

. Addition of IGF-I to culture medium reduced accumulation of bax, MAPK, and IGF-I and promoted PKA accumulation and E 2 release. CR promoted the stimulatory effect of IGF-I on E 2 output. Thus, CR can increase rabbit fecundity, probably via changes in IGF-I, leptin and steroid hormones released, which in turn can affect ovarian cell cycle, apoptosis, and response to IGF-I. Furthermore, they demonstrate the stimulatory influence of IGF-I on rabbit fecundity, which was associated with changes in plasma leptin, E 2 and ovarian cell apoptosis, PKA, MAPK, IGF-I and E 2 release. The promotion of IGF-I output by CR and the ability of IGF-I to mimic/replace but not to modify CR effects on fecundity, plasma IGF-I, and ovarian cell apoptosis suggest that IGF can mediate the action of CR on these reproductive indexes. In contrast, differences in the action of CR and IGF-I on other hormones, ovarian cell proliferation, protein kinases and IGF-I suggest that CR action on these indexes is not mediated by IGF-I. We thus demonstrate that both CR and IGF-I administration can increase rabbit fecundity, and that their effects can be mediated by changes in reproductive hormones, ovarian cell proliferation, apoptosis, and the response of ovarian cells to IGF-I. Copyright © 2016 Elsevier Inc. All rights reserved.

40 CFR 1.27 - Offices of the Associate Administrators.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Agency decision-making processes, assessing the impact of Headquarters actions on Regional operations... Regional Operations. The Office of Regional Operations, under the supervision of an Associate Administrator... communications link between the Administrator/Deputy Administrator and the Regional Administrators. It provides a...

78 FR 62417 - Import Administration; Change of Agency Name

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

... DEPARTMENT OF COMMERCE International Trade Administration 19 CFR Parts 351, 354, and 356 RIN 0625-AA97 [Docket No. 130927845-3845-01] Import Administration; Change of Agency Name AGENCY: Import Administration, International Trade Administration, Commerce. ACTION: Final rule; nomenclature change. SUMMARY...

10 CFR 4.340 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 1 2010-01-01 2010-01-01 false Exhaustion of administrative remedies. 4.340 Section 4.340... administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act. Administrative remedies are exhausted if— (1) 180 days have elapsed since the...

77 FR 64843 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-23

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on.... ACTION: Notice of actions on Special Permit Applications. SUMMARY: In accordance with the procedures...'s Hazardous Material Regulations (49 CFR part 107, subpart B), notice is hereby given of the actions...

78 FR 24305 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-24

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on.... ACTION: Notice of actions on Special Permit Applications. SUMMARY: In accordance with the procedures...'s Hazardous Material Regulations (49 CFR Part 107, Subpart B), notice is hereby given of the actions...

77 FR 49483 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-16

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on.... ACTION: Notice of actions on Special Permit Applications. SUMMARY: In accordance with the procedures...'s Hazardous Material Regulations (49 CFR Part 107, Subpart B), notice is hereby given of the actions...

78 FR 30394 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-22

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on.... ACTION: Notice of actions on Special Permit Applications. SUMMARY: In accordance with the procedures...'s Hazardous Material Regulations (49 CFR part 107, subpart B), notice is hereby given of the actions...

77 FR 29450 - Actions on Special Permit Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-17

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Actions on.... ACTION: Notice of actions on Special Permit Applications. SUMMARY: In accordance with the procedures...'s Hazardous Material Regulations (49 CFR part 107, subpart B), notice is hereby given of the actions...

34 CFR 303.424 - Civil action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true Civil action. 303.424 Section 303.424 Education... Civil action. Any party aggrieved by the findings and decision regarding an administrative complaint has the right to bring a civil action in State or Federal court under section 639(a)(1) of the Act...

34 CFR 303.424 - Civil action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false Civil action. 303.424 Section 303.424 Education... Civil action. Any party aggrieved by the findings and decision regarding an administrative complaint has the right to bring a civil action in State or Federal court under section 639(a)(1) of the Act...

76 FR 7893 - FAA Policy Statement on Expungement of Certain Enforcement Actions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-11

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration FAA Policy Statement on Expungement of Certain Enforcement Actions AGENCY: Federal Aviation Administration, DOT. ACTION: Policy statement... policy. On August 1, 2010, the Airline Safety and Federal Aviation Administration Extension Act of 2010...

Brain regions mediating α3β4 nicotinic antagonist effects of 18-MC on nicotine self-administration

PubMed Central

Glick, Stanley D.; Sell, Elizabeth M.; McCallum, Sarah E; Maisonneuve, Isabelle M.

2011-01-01

18-methoxycoronaridine (18-MC), a putative anti-addictive agent, has been shown to decrease the self-administration of several drugs of abuse in rats. 18-MC is a potent antagonist at α3β4 nicotinic receptors. Consistent with high densities of α3β4 nicotinic receptors being located in the medial habenula and the interpeduncular nucleus, 18-MC has been shown to act in these regions to decrease both morphine and methamphetamine self-administration. The present study was conducted to determine if 18-MC’s effect on nicotine self-administration is mediated by acting in these same brain regions. Because moderate densities of α3β4 receptors occur in the dorsolateral tegmentum, ventral tegmental area, and basolateral amygdala, these brain areas were also examined as potential sites of action of 18-MC. Local administration of 18-MC into either the medial habenula, the basolateral amygdala or the dorsolateral tegmentum decreased nicotine self-administration. Surprisingly, local administration of 18-MC into the interpeduncular nucleus increased nicotine self-administration while local administration of 18-MC into the ventral tegmental area had no effect on nicotine self-administration. Similar effects were produced by local administration of either mecamylamine or conotoxin AuIB. These data are consistent with the hypothesis that 18-MC decreases nicotine self-administration by indirectly modulating the dopaminergic mesolimbic pathway via blockade of α3β4 nicotinic receptors in the medial habenula, basolateral amygdala, and dorsolateral tegmentum. The data also suggest that an action of 18-MC in the interpeduncular nucleus may attenuate aversive and/or depressive effects of nicotine. PMID:21871879

Corrective Action Decision Document/Corrective Action Plan for Corrective Action Unit 547: Miscellaneous Contaminated Waste Sites, Nevada National Security Site, Nevada, Revision 0

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mark Krauss

2011-09-01

The purpose of this CADD/CAP is to present the corrective action alternatives (CAAs) evaluated for CAU 547, provide justification for selection of the recommended alternative, and describe the plan for implementing the selected alternative. Corrective Action Unit 547 consists of the following three corrective action sites (CASs): (1) CAS 02-37-02, Gas Sampling Assembly; (2) CAS 03-99-19, Gas Sampling Assembly; and(3) CAS 09-99-06, Gas Sampling Assembly. The gas sampling assemblies consist of inactive process piping, equipment, and instrumentation that were left in place after completion of underground safety experiments. The purpose of these safety experiments was to confirm that a nuclearmore » explosion would not occur in the case of an accidental detonation of the high-explosive component of the device. The gas sampling assemblies allowed for the direct sampling of the gases and particulates produced by the safety experiments. Corrective Action Site 02-37-02 is located in Area 2 of the Nevada National Security Site (NNSS) and is associated with the Mullet safety experiment conducted in emplacement borehole U2ag on October 17, 1963. Corrective Action Site 03-99-19 is located in Area 3 of the NNSS and is associated with the Tejon safety experiment conducted in emplacement borehole U3cg on May 17, 1963. Corrective Action Site 09-99-06 is located in Area 9 of the NNSS and is associated with the Player safety experiment conducted in emplacement borehole U9cc on August 27, 1964. The CAU 547 CASs were investigated in accordance with the data quality objectives (DQOs) developed by representatives of the Nevada Division of Environmental Protection (NDEP) and the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office. The DQO process was used to identify and define the type, amount, and quality of data needed to determine and implement appropriate corrective actions for CAU 547. Existing radiological survey data and historical

40 CFR 73.84 - Administrator's action on applications.

Code of Federal Regulations, 2013 CFR

2013-07-01

... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation. (1) The Administrator will not award allowances to more...

40 CFR 73.84 - Administrator's action on applications.

Code of Federal Regulations, 2012 CFR

2012-07-01

... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation.(1) The Administrator will not award allowances to more...

40 CFR 73.84 - Administrator's action on applications.

Code of Federal Regulations, 2014 CFR

2014-07-01

... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation. (1) The Administrator will not award allowances to more...

40 CFR 73.84 - Administrator's action on applications.

Code of Federal Regulations, 2011 CFR

2011-07-01

... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation.(1) The Administrator will not award allowances to more...

40 CFR 73.84 - Administrator's action on applications.

Code of Federal Regulations, 2010 CFR

2010-07-01

... PROGRAMS (CONTINUED) SULFUR DIOXIDE ALLOWANCE SYSTEM Energy Conservation and Renewable Energy Reserve § 73... categories of qualified renewable energy generation enumerated in § 73.81(c)(2)(i) and appendix A(3.1-3.4... conservation measures or renewable energy generation.(1) The Administrator will not award allowances to more...

78 FR 63380 - Farm Credit Administration Board Policy Statements

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-24

... FARM CREDIT ADMINISTRATION 12 CFR Chapter VI Farm Credit Administration Board Policy Statements AGENCY: Farm Credit Administration. ACTION: Notice of policy statements and index. SUMMARY: The Farm Credit Administration (FCA), as part of its annual public notification process, is publishing for notice...

42 CFR 93.506 - Authority of the Administrative Law Judge.

Code of Federal Regulations, 2011 CFR

2011-10-01

... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.506 Authority of the Administrative Law Judge. (a) The ALJ assigned... communication; (17) Take action against any party for failing to follow an order or procedure or for disruptive...

40 CFR 264.222 - Action leakage rate.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Action leakage rate. 264.222 Section... Impoundments § 264.222 Action leakage rate. (a) The Regional Administrator shall approve an action leakage rate for surface impoundment units subject to § 264.221 (c) or (d). The action leakage rate is the maximum...

40 CFR 264.252 - Action leakage rate.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Action leakage rate. 264.252 Section... Piles § 264.252 Action leakage rate. (a) The Regional Administrator shall approve an action leakage rate for waste pile units subject to § 264.251(c) or (d). The action leakage rate is the maximum design...

76 FR 65183 - National Oceanic and Atmospheric Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-20

... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration National Climate Assessment... Oceanic and Atmospheric Administration (NOAA), Department of Commerce (DOC). ACTION: Notice of open..., National Oceanic and Atmospheric Administration. [FR Doc. 2011-27113 Filed 10-19-11; 8:45 am] BILLING CODE...

Enhanced actions of insulin-like growth factor-I and interferon-alpha co-administration in experimental cirrhosis.

PubMed

Tutau, Federico; Rodríguez-Ortigosa, Carlos; Puche, Juan Enrique; Juanarena, Nerea; Monreal, Iñigo; García Fernández, María; Clavijo, Encarna; Castilla, Alberto; Castilla-Cortázar, Inma

2009-01-01

Cirrhosis is a diffuse process of hepatic fibrosis and regenerative nodule formation. The liver is the major source of circulating insulin-like growth factor-I (IGF-I) whose plasma levels are diminished in cirrhosis. IGF-I supplementation has been shown to induce beneficial effects in cirrhosis, including antifibrogenic and hepatoprotective effects. On other hand, interferon-alpha (IFN-alpha) therapy seems to suppress the progression of hepatic fibrosis. The aim of this study was to investigate the effect of the co-administration of IGF-I+IFN-alpha to Wistar rats with CCl(4)-induced cirrhosis, exploring liver function tests, hepatic lipid peroxidation and histopathology. The mechanisms underlying the effects of these agents were studied by reverse transcription-polymerase chain reaction, determining the expression of some factors [hepatocyte growth factor (HGF), transforming growth factor-beta (TGF-beta), alpha-smooth muscle actin, collagen, tissular inhibitor of metalloproteinases-1 and pregnane X receptor (PXR)] involved in fibrogenesis, fibrolysis and/or hepatoprotection. Both IGF-I and IFN-alpha exerted significant effects on fibrogenesis. IGF-I significantly increased serum albumin and HGF whereas IFN-alpha-therapy did not. The inhibition of TGF-beta expression was only observed by the effect of IFN-alpha-therapy. In addition, only the co-administration of IGF-I and IFN-alpha was able to increase the PXR. The combined therapy with both factors improved liver function tests, hepatic lipid peroxidation and reduced fibrosis, inducing a relevant histological improvement, reducing fibrosis and recovering hepatic architecture. The co-administration IGF-I+IFN enhanced all the beneficial effects observed with each factor separately, showing an additive action on histopathology and PXR expression, which is involved in the inhibition of fibrogenesis.

Proactive action preparation: seeing action preparation as a continuous and proactive process.

PubMed

Pezzulo, Giovanni; Ognibene, Dimitri

2012-07-01

In this paper, we aim to elucidate the processes that occur during action preparation from both a conceptual and a computational point of view. We first introduce the traditional, serial model of goal-directed action and discuss from a computational viewpoint its subprocesses occurring during the two phases of covert action preparation and overt motor control. Then, we discuss recent evidence indicating that these subprocesses are highly intertwined at representational and neural levels, which undermines the validity of the serial model and points instead to a parallel model of action specification and selection. Within the parallel view, we analyze the case of delayed choice, arguing that action preparation can be proactive, and preparatory processes can take place even before decisions are made. Specifically, we discuss how prior knowledge and prospective abilities can be used to maximize utility even before deciding what to do. To support our view, we present a computational implementation of (an approximated version of) proactive action preparation, showing its advantages in a simulated tennis-like scenario.

36 CFR 223.198 - Administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Administrative remedies. 223.198 Section 223.198 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE SALE... Act of 1990 Program § 223.198 Administrative remedies. In addition to possible debarment action...

42 CFR 405.1875 - Administrator review.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Appeals § 405.1875 Administrator review. (a) Basic rule: Time limit for rendering Administrator decisions... after the date the party making the request received the Board's decision or other reviewable action... decision or other reviewable matter. (ii) Any submission must be limited to the issues accepted for...

Faculty: Thy Administrator's Keeper? Some Evidence

ERIC Educational Resources Information Center

Cunningham, Brendan M.

2009-01-01

Colleges and universities face a principal-agent problem. There are information asymmetries over the actions chosen by administrators. Because non-profit constraints limit the financial stake of trustees there may be insufficient monitoring of administrators and, consequentially, shirking. It is conceivable that faculty will serve as "delegated…

[Therapeutic administration of immunoglobulins].

PubMed

Witte, T

2016-12-01

Intravenously administered immunoglobulins have multiple modes of action that are anti-inflammatory. They can therefore be beneficial in a number of autoimmune disorders. The aim of this article is to analyze and summarize studies on the administration of intravenous immunoglobulins in rheumatological diseases. A selective search and analysis of the literature was carried out related to the mode of action and efficacy of intravenous immunoglobulins in rheumatological diseases. Intravenous immunoglobulins have a broad mode of action and can therefore be beneficial in almost all autoimmune diseases. Conditions in which they are of special benefit include immunothrombopenia (ITP), Kawasaki disease and idiopathic inflammatory myopathies. In rare situations, they may also be indicated in systemic lupus erythematosus (SLE), Sjögren's syndrome and neuropathies, catastrophic antiphospholipid syndrome (APS), scleroderma, antineutrophil cytoplasmic antibody (ANCA) associated vasculitis, pyoderma gangrenosum and scleromyxedema. Severe adverse events are rare. In view of the high costs of the therapy, intravenous immunoglobulins are mostly applied in emergency situations, as salvage therapy when other standard therapies have failed or when severe infections are a contraindication to the administration of immunosuppressants.

40 CFR 264.302 - Action leakage rate.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Action leakage rate. 264.302 Section... § 264.302 Action leakage rate. (a) The Regional Administrator shall approve an action leakage rate for landfill units subject to § 264.301(c) or (d). The action leakage rate is the maximum design flow rate that...

14 CFR 1252.410 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Exhaustion of administrative remedies. 1252..., Conciliation, and Enforcement Procedures § 1252.410 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

42 CFR 8.32 - Administrative record.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Administrative record. 8.32 Section 8.32 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF..., and of Adverse Action Regarding Withdrawal of Approval of an Accreditation Body § 8.32 Administrative...

42 CFR 8.32 - Administrative record.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Administrative record. 8.32 Section 8.32 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS CERTIFICATION OF..., and of Adverse Action Regarding Withdrawal of Approval of an Accreditation Body § 8.32 Administrative...

18 CFR 808.2 - Administrative appeals.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Administrative appeals. 808.2 Section 808.2 Conservation of Power and Water Resources SUSQUEHANNA RIVER BASIN COMMISSION HEARINGS AND ENFORCEMENT ACTIONS Conduct of Hearings § 808.2 Administrative appeals. (a) A project sponsor...

48 CFR 522.804 - Affirmative action programs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Affirmative action programs. 522.804 Section 522.804 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION... Affirmative action programs. ...

48 CFR 522.804 - Affirmative action programs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Affirmative action programs. 522.804 Section 522.804 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION... Affirmative action programs. ...

28 CFR 61.4 - Major federal action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ENVIRONMENTAL POLICY ACT General § 61.4 Major federal action. The NEPA regulations define “major federal action... judicial or administrative enforcement proceedings or civil or criminal litigation, including but not...

41 CFR 101-8.724 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-07-01

... administrative remedies. 101-8.724 Section 101-8.724 Public Contracts and Property Management Federal Property... Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act. Administrative remedies are exhausted if: (1) 180 calendar days elapse...

41 CFR 101-8.724 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... administrative remedies. 101-8.724 Section 101-8.724 Public Contracts and Property Management Federal Property... Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act. Administrative remedies are exhausted if: (1) 180 calendar days elapse...

Affirmative Action Employment Plan. Revised.

ERIC Educational Resources Information Center

Oakland Unified School District, CA.

This is the affirmative action employment plan adopted by the Board of Education of the Oakland Unified School District, Oakland, California. A statement of school district policy and goals is provided. Responsibilities of the school district administrators and the Affirmative Action Advisory Committee are also outlined. Steps to be taken to…

76 FR 45332 - Pipeline and Hazardous Materials Safety Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-28

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration Office of... Hazardous Materials Safety Administration (PHMSA), DOT. ACTION: List of Applications for Modification of..., 2011. ADDRESSES: Record Center, Pipeline and Hazardous Materials Safety Administration, U.S. Department...

43 CFR 17.339 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Exhaustion of administrative remedies. 17... Investigation, Conciliation, and Enforcement Procedures § 17.339 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

45 CFR 91.50 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Exhaustion of administrative remedies. 91.50... Investigation, Conciliation, and Enforcement Procedures § 91.50 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

45 CFR 91.50 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Exhaustion of administrative remedies. 91.50... Investigation, Conciliation, and Enforcement Procedures § 91.50 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

45 CFR 1156.21 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false Exhaustion of administrative remedies. 1156.21... Investigation, Conciliation, and Enforcement Procedures § 1156.21 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

Student Voice in High School: An Action Research Study

ERIC Educational Resources Information Center

Termini, Lorraine

2013-01-01

This action research study examined the effects of student voice in one high school and the self-reflection of the researcher-administrator involved in the effort. Using three cycles of action research, the researcher-administrator completed a pilot study, implemented a student voice project in one class, and developed a professional development…

12 CFR 263.22 - Consolidation and severance of actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Consolidation and severance of actions. (a) Consolidation. (1) On the motion of any party, or on the administrative law judge's own motion, the administrative law judge may consolidate, for some or all purposes... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Consolidation and severance of actions. 263.22...

12 CFR 308.22 - Consolidation and severance of actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... severance of actions. (a) Consolidation. (1) On the motion of any party, or on the administrative law judge's own motion, the administrative law judge may consolidate, for some or all purposes, any two or... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Consolidation and severance of actions. 308.22...

12 CFR 509.22 - Consolidation and severance of actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Consolidation and severance of actions. (a) Consolidation. (1) On the motion of any party, or on the administrative law judge's own motion, the administrative law judge may consolidate, for some or all purposes... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Consolidation and severance of actions. 509.22...

76 FR 27002 - Information Collection; National Recreation Program Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-10

... Administration AGENCY: Forest Service, USDA. ACTION: Notice; request for comment. SUMMARY: In accordance with the... organizations on the new information collection, National Recreation Program Administration. DATES: Comments... holidays. SUPPLEMENTARY INFORMATION: Title: National Recreation Program Administration. OMB Number: 0596...

25 CFR 700.479 - Administrative review.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Administrative review. 700.479 Section 700.479 Indians... Discretionary Funds § 700.479 Administrative review. (a) If the Commissioners determine that implementation of... is terminated or suspended under paragraph (b) of this section may request a review of such action by...

Convergent mechanisms underlying rapid antidepressant action

PubMed Central

Zanos, Panos; Thompson, Scott M.; Duman, Ronald S.; Zarate, Carlos A.; Gould, Todd D.

2018-01-01

Traditional pharmacological treatments for depression have a delayed therapeutic onset, ranging from several weeks to months, and there is a high percentage of individuals who never respond to treatment. In contrast, ketamine produces rapid-onset antidepressant, anti-suicidal and anti-anhedonic actions following a single administration to depressed patients. Proposed mechanisms of ketamine’s antidepressant action include N-methyl-D-aspartate receptor (NMDAR) modulation, GABAergic interneuron disinhibition, and direct actions of its hydroxynorketamine (HNK) metabolites. Downstream actions include activation of mechanistic target of rapamycin (mTOR), deactivation of glycogen synthase kinase-3 and eukaryotic elongation factor 2 (eEF2), enhanced brain-derived neurotrophic factor (BDNF) signaling, and activation of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptors (AMPARs). These putative mechanisms of ketamine action are not mutually exclusive and may complement each other to induce potentiation of excitatory synapses in affective-regulating brain circuits, which results in amelioration of depression symptoms. We review these proposed mechanisms of ketamine action in the context of how such mechanisms are informing the development of novel putative rapid-acting antidepressant drugs. Such drugs that have undergoing pre-clinical, and in some cases clinical, testing include the muscarinic acetylcholine receptor antagonist scopolamine, GluN2B-NMDAR antagonists (i.e., CP-101,606, MK-0657), (2R,6R)-HNK, NMDAR glycine site modulators (i.e., 4-chlorokynurenine - pro-drug of the glycineB NMDAR antagonist 7-chlorokynurenic acid), NMDAR agonists (i.e. GLYX-13 (rapastinel)), metabotropic glutamate receptor 2/3 (mGluR2/3) antagonists, GABAA receptor modulators, and drugs acting on various serotonin receptor subtypes. These ongoing studies suggest that the future acute treatment of depression will typically occur within hours, rather than months, of treatment

23 CFR 140.605 - Approval actions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Approval actions. 140.605 Section 140.605 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Bond Issue Projects § 140.605 Approval actions. (a) Authorization to proceed with preliminary...

23 CFR 140.605 - Approval actions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Approval actions. 140.605 Section 140.605 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Bond Issue Projects § 140.605 Approval actions. (a) Authorization to proceed with preliminary...

23 CFR 140.605 - Approval actions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Approval actions. 140.605 Section 140.605 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Bond Issue Projects § 140.605 Approval actions. (a) Authorization to proceed with preliminary...

23 CFR 140.605 - Approval actions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Approval actions. 140.605 Section 140.605 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PAYMENT PROCEDURES REIMBURSEMENT Reimbursement for Bond Issue Projects § 140.605 Approval actions. (a) Authorization to proceed with preliminary...

78 FR 69288 - Import Administration; Change of Agency Name

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-19

...] RIN 0625-AA98 Import Administration; Change of Agency Name AGENCY: Foreign-Trade Zones Board, International Trade Administration, Commerce. ACTION: Final rule; nomenclature change. SUMMARY: Effective... orders, changed the name of ``Import Administration'' to ``Enforcement and Compliance.'' Consistent with...

40 CFR 7.175 - Exhaustion of administrative remedy.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Exhaustion of administrative remedy. 7... Discrimination Prohibited on the Basis of Age § 7.175 Exhaustion of administrative remedy. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Age Discrimination...

24 CFR 146.45 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-04-01

... remedies. 146.45 Section 146.45 Housing and Urban Development Regulations Relating to Housing and Urban... Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act. Administrative remedies are exhausted if: (1) 180 days have elapsed since...

40 CFR 7.175 - Exhaustion of administrative remedy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Exhaustion of administrative remedy. 7... Discrimination Prohibited on the Basis of Age § 7.175 Exhaustion of administrative remedy. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Age Discrimination...

75 FR 53975 - Administration for Native Americans; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-02

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Administration..., Administration for Children and Families. ACTION: Notice of Tribal Consultation. SUMMARY: The Department of Health and Human Services (HHS), Administration for Children and Families (ACF) will host a tribal...

Neuroprotective action and free radical scavenging activity of Guttiferone-A, a naturally occurring prenylated benzophenone.

PubMed

Nuñez-Figueredo, Y; García-Pupo, L; Ramírez-Sánchez, J; Alcántara-Isaac, Y; Cuesta-Rubio, O; Hernández, R D; Naal, Z; Curti, C; Pardo-Andreu, G L

2012-12-01

Reactive oxygen species (ROS) are important mediators in a number of neurodegenerative diseases and molecules capable of scavenging ROS may be a feasible strategy for protecting neuronal cells. We previously demonstrated a powerful iron-chelating action of Guttiferone-A (GA), a naturally occurring polyphenol, on oxidative stress injuries initiated by iron overload. Here we addressed the neuroprotective potential of GA in hydrogen peroxide and glutamate-induced injury on rat's primary culture of cortical neurons and PC12 cells, respectively, and antioxidant properties concerning scavenging and anti-lipoperoxidative activities in cell-free models. The decrease in cell viability induced by each of the toxins, assessed by [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] (MTT) assay, was significantly attenuated by GA. In addition, GA was found to be a potent antioxidant, as shown by (i) inhibition of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical reduction (EC50=20.0 μM), (ii) prevention against chemically or electrochemically generated superoxide radicals, (iii) inhibition of spontaneous brain lipid peroxidation and (iv) interference with the Fenton reaction. These results indicate that GA exerts neuroprotective effects against H2O2 or glutamate toxicity and its antioxidant activity, demonstrated in vitro, could be at least partly involved. They also suggest a promising potential for GA as a therapeutic agent against neurodegenerative diseases involving ROS and oxidative damage. © Georg Thieme Verlag KG Stuttgart · New York.

Mechanisms of Hormone Action

PubMed Central

Abeles, F. B.; Ruth, J. M.; Forrence, L. E.; Leather, G. R.

1972-01-01

We observed no exchange between deuterated ethylene (C2D4) and the hydrogen of pea seedlings (Pisum sativum L. cv. Alaska). This suggests that bonding forces in which exchange could readily occur are not important in the physiological action of ethylene. Deuterated ethylene was just as effective as normal ethylene in inhibiting the growth of pea root sections. These results indicate that splitting carbon to hydrogen bonds did not occur during ethylene action. PMID:16658026

From Headline to Hard Grind: The Importance of Understanding Public Administration in Achieving Health OutcomesComment on "Understanding the Role of Public Administration in Implementing Action on the Social Determinants of Health and Health Inequities".

PubMed

O'Flynn, Janine

2016-04-30

Many public policy programs fail to translate ambitious headlines to on-the-ground action. The reasons for this are many and varied, but for public administration and management scholars a large part of the gap between ambition and achievement is the challenge associated with the operation of the machinery of government itself, and how it relates to the other parties that it relies on to fulfill these outcomes. In their article, Carey and Friel set out key reasons why public health scholars should seek to better understand important ideas in public administration. In commenting on their contribution, I draw out two critical questions that are raised by this discussion: (i) what are boundaries and what forms do they take? and (ii) why work across boundaries? Expanding on these key questions extends the points made by Carey and Friel on the importance of understanding public administration and will better place public health scholars and practitioners to realise health outcomes. © 2016 by Kerman University of Medical Sciences.

14 CFR 161.415 - Reevaluation action.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Reevaluation action. 161.415 Section 161.415 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED... § 161.415 Reevaluation action. (a) Upon completing the reevaluation, the FAA will issue appropriate...

National Credit Union Administration Semiannual Regulatory Agenda

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-26

... only the minimum required burdens on credit unions, consumers, and the public; are appropriate for the... Administration--Completed Actions Regulation Sequence Title Identifier Number Number 412 Privacy of Consumer... Actions 412. PRIVACY OF CONSUMER FINANCIAL INFORMATION Legal Authority: 15 USC 6801 et seq Abstract: NCUA...

40 CFR 265.302 - Action leakage rate.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Action leakage rate. 265.302 Section... FACILITIES Landfills § 265.302 Action leakage rate. (a) The owner or operator of landfill units subject to § 265.301(a) must submit a proposed action leakage rate to the Regional Administrator when submitting...

75 FR 31744 - Information Collection; Contract Operations and Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-04

... Administration AGENCY: Forest Service, USDA. ACTION: Notice; request for comment. SUMMARY: In accordance with the... organizations on a new information collection, Contract Operations and Administration. DATES: Comments must be... INFORMATION: Title: Contract Operations and Administration. OMB Number: 0596-NEW. Expiration Date of Approval...

77 FR 40069 - Single-Ingredient, Immediate-Release Drug Products Containing Oxycodone for Oral Administration...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0563... Labeled for Human Use; Enforcement Action Dates AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA or Agency) is announcing its intention to take enforcement...

Representing the Hyphen in Action-Effect Associations: Automatic Acquisition and Bidirectional Retrieval of Action-Effect Intervals

ERIC Educational Resources Information Center

Dignath, David; Pfister, Roland; Eder, Andreas B.; Kiesel, Andrea; Kunde, Wilfried

2014-01-01

We examined whether a temporal interval between an action and its sensory effect is integrated in the cognitive action structure in a bidirectional fashion. In 3 experiments, participants first experienced that actions produced specific acoustic effects (high and low tones) that occurred temporally delayed after their actions. In a following test…

14 CFR 91.103 - Preflight action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Preflight action. 91.103 Section 91.103 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC... action. Each pilot in command shall, before beginning a flight, become familiar with all available...

14 CFR 91.103 - Preflight action.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Preflight action. 91.103 Section 91.103 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC... action. Each pilot in command shall, before beginning a flight, become familiar with all available...

40 CFR 265.255 - Action leakage rates.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Action leakage rates. 265.255 Section... FACILITIES Waste Piles § 265.255 Action leakage rates. (a) The owner or operator of waste pile units subject to § 265.254 must submit a proposed action leakage rate to the Regional Administrator when submitting...

5 CFR 2636.104 - Civil, disciplinary and other action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Civil, disciplinary and other action... Provisions § 2636.104 Civil, disciplinary and other action. (a) Civil action. Except when the employee... prohibited conduct, whichever is greater. (b) Disciplinary and corrective action. An agency may initiate...

28 CFR 104.61 - Limitation on civil actions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Limitation on civil actions. 104.61... COMPENSATION FUND OF 2001 Limitations § 104.61 Limitation on civil actions. (a) General. Section 405(c)(3)(B... to file a civil action (or be a party to an action) in any Federal or State court for damages...

28 CFR 104.61 - Limitation on civil actions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Limitation on civil actions. 104.61... COMPENSATION FUND Limitations § 104.61 Limitation on civil actions. (a) General. Section 405(c)(3)(C) of the... a civil action (or be a party to an action) in any Federal or State court for damages sustained as a...

28 CFR 104.61 - Limitation on civil actions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Limitation on civil actions. 104.61... COMPENSATION FUND OF 2001 Limitations § 104.61 Limitation on civil actions. (a) General. Section 405(c)(3)(B... to file a civil action (or be a party to an action) in any Federal or State court for damages...

12 CFR 1008.309 - Absence of liability for good-faith administration.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 8 2013-01-01 2013-01-01 false Absence of liability for good-faith... for Administration of the NMLSR § 1008.309 Absence of liability for good-faith administration. The... action or proceeding for monetary damages by reason of the good-faith action or omission of any officer...

12 CFR 1008.309 - Absence of liability for good-faith administration.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 8 2012-01-01 2012-01-01 false Absence of liability for good-faith... for Administration of the NMLSR § 1008.309 Absence of liability for good-faith administration. The... action or proceeding for monetary damages by reason of the good-faith action or omission of any officer...

12 CFR 1008.309 - Absence of liability for good-faith administration.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 8 2014-01-01 2014-01-01 false Absence of liability for good-faith... for Administration of the NMLSR § 1008.309 Absence of liability for good-faith administration. The... action or proceeding for monetary damages by reason of the good-faith action or omission of any officer...

77 FR 22358 - Occupational Safety and Health Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-13

... DEPARTMENT OF LABOR Occupational Safety and Health Administration Preparations for the 23rd...: Occupational Safety and Health Administration (OSHA), Labor. ACTION: Notice of public meeting. SUMMARY: OSHA... health, physical, and environmental effects. It also provides harmonized communication elements...

76 FR 8400 - National Highway Traffic Safety Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-14

... DEPARTMENT OF TRANSPORTATION National Highway Traffic Safety Administration Petition for Exemption From the Vehicle Theft Prevention Standard; Mitsubishi Motors AGENCY: National Highway Traffic Safety Administration (NHTSA) Department of Transportation (DOT). ACTION: Grant of petition for exemption. SUMMARY: This...

18 CFR 401.7 - Further action.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 18 Conservation of Power and Water Resources 2 2011-04-01 2011-04-01 false Further action. 401.7 Section 401.7 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Comprehensive Plan § 401.7 Further action. The Commission will...

18 CFR 401.7 - Further action.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Further action. 401.7 Section 401.7 Conservation of Power and Water Resources DELAWARE RIVER BASIN COMMISSION ADMINISTRATIVE MANUAL RULES OF PRACTICE AND PROCEDURE Comprehensive Plan § 401.7 Further action. The Commission will...

76 FR 30236 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0061] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 31004 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0069] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 18300 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD-2011 0031] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 24563 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-02

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0040] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 28846 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-18

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0055] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 31007 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0066] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 55734 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0014] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 55734 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0012] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 24563 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-02

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0042] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 6183 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-03

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0001] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 26793 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-09

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD 2011 0041] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 28846 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-18

... DEPARTMENT OF TRANSPORTATION Maritime Administration Docket No. MARAD-2011-0052 Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 51467 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0105] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 30237 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0054] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 55733 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0113] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 29332 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-20

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0053] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 31007 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0065] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 35943 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-20

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0075] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 18299 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD 2011-0032] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 13701 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-14

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD-2011 0024] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 31006 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-27

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011-0064] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 30755 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-26

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2011 0068] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

76 FR 18299 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-01

... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD 2011 0034] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws...

Investigating action understanding: inferential processes versus action simulation.

PubMed

Brass, Marcel; Schmitt, Ruth M; Spengler, Stephanie; Gergely, György

2007-12-18

In our daily life, we continuously monitor others' behaviors and interpret them in terms of goals, intentions, and reasons. Despite their central importance for predicting and interpreting each other's actions, the functional mechanisms and neural circuits involved in action understanding remain highly controversial. Two alternative accounts have been advanced. Simulation theory assumes that we understand actions by simulating the observed behavior through a direct matching process that activates the mirror-neuron circuit. The alternative interpretive account assumes that action understanding is based on specialized inferential processes activating brain areas with no mirror properties. Although both approaches recognize the central role of contextual information in specifying action intentions, their respective accounts of this process differ in significant respects. Here, we investigated the role of context in action understanding by using functional brain imaging while participants observed an unusual action in implausible versus plausible contexts. We show that brain areas that are part of a network involved in inferential interpretive processes of rationalization and mentalization but that lack mirror properties are more active when the action occurs in an implausible context. However, no differential activation was found in the mirror network. Our findings support the assumption that action understanding in novel situations is primarily mediated by an inferential interpretive system rather than the mirror system.

78 FR 14806 - Health Resources and Services Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-07

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Statement of Organization, Functions and Delegations of Authority; Correction AGENCY: Health Resources and Services Administration (HRSA), HHS. ACTION: Notice; correction. SUMMARY: HRSA published a document in the Federal...

77 FR 66910 - Notice of Final Federal Agency Actions on Proposed Highway in California

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-07

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Notice of Final Federal Agency Actions on Proposed Highway in California AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice...). A claim seeking judicial review of the Federal agency actions on the highway project will be barred...

32 CFR 1901.44 - Action by appeals authority.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Action by appeals authority. 1901.44 Section 1901.44 National Defense Other Regulations Relating to National Defense CENTRAL INTELLIGENCE AGENCY PUBLIC RIGHTS UNDER THE PRIVACY ACT OF 1974 Action on Privacy Act Administrative Appeals § 1901.44 Action...

32 CFR 1901.44 - Action by appeals authority.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Action by appeals authority. 1901.44 Section 1901.44 National Defense Other Regulations Relating to National Defense CENTRAL INTELLIGENCE AGENCY PUBLIC RIGHTS UNDER THE PRIVACY ACT OF 1974 Action on Privacy Act Administrative Appeals § 1901.44 Action...

28 CFR 42.724 - Remedial and affirmative action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Remedial and affirmative action. 42.724... affirmative action. (a) If the Department finds that, in violation of this subpart, a recipient has discriminated on the basis of age, the recipient shall take remedial action that the Department considers...

28 CFR 42.724 - Remedial and affirmative action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Remedial and affirmative action. 42.724... affirmative action. (a) If the Department finds that, in violation of this subpart, a recipient has discriminated on the basis of age, the recipient shall take remedial action that the Department considers...

78 FR 57445 - Charging Standard Administrative Fees for Nonprogram-Related Information

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-18

... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA-2012-0026] Charging Standard Administrative Fees for Nonprogram-Related Information AGENCY: Social Security Administration. ACTION: Notice of standard... administration of a program under the Social Security Act (Act). SUPPLEMENTARY INFORMATION: Section 1106 of the...

29 CFR 1990.147 - Final action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 9 2010-07-01 2010-07-01 false Final action. 1990.147 Section 1990.147 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED... Occupational Carcinogens § 1990.147 Final action. (a) Within one hundred twenty (120) days from the last day of...

10 CFR 1040.89-13 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Exhaustion of administrative remedies. 1040.89-13 Section... Investigation, Conciliation and Enforcement Procedures § 1040.89-13 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

10 CFR 1040.89-13 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Exhaustion of administrative remedies. 1040.89-13 Section... Investigation, Conciliation and Enforcement Procedures § 1040.89-13 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

42 CFR 456.407 - UR responsibilities of administrative staff.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 4 2014-10-01 2014-10-01 false UR responsibilities of administrative staff. 456... administrative staff. The UR plan must describe— (a) The UR support responsibilities of the ICF's administrative staff; and (b) Procedures used by the staff for taking needed corrective action. UR Plan: Informational...

42 CFR 456.407 - UR responsibilities of administrative staff.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 4 2012-10-01 2012-10-01 false UR responsibilities of administrative staff. 456... administrative staff. The UR plan must describe— (a) The UR support responsibilities of the ICF's administrative staff; and (b) Procedures used by the staff for taking needed corrective action. UR Plan: Informational...

42 CFR 456.407 - UR responsibilities of administrative staff.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false UR responsibilities of administrative staff. 456... administrative staff. The UR plan must describe— (a) The UR support responsibilities of the ICF's administrative staff; and (b) Procedures used by the staff for taking needed corrective action. UR Plan: Informational...

42 CFR 456.407 - UR responsibilities of administrative staff.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 4 2013-10-01 2013-10-01 false UR responsibilities of administrative staff. 456... administrative staff. The UR plan must describe— (a) The UR support responsibilities of the ICF's administrative staff; and (b) Procedures used by the staff for taking needed corrective action. UR Plan: Informational...

42 CFR 456.407 - UR responsibilities of administrative staff.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 4 2011-10-01 2011-10-01 false UR responsibilities of administrative staff. 456... administrative staff. The UR plan must describe— (a) The UR support responsibilities of the ICF's administrative staff; and (b) Procedures used by the staff for taking needed corrective action. UR Plan: Informational...

40 CFR 35.6815 - Administrative requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Requirements for Administering A Superfund State Contract (ssc) § 35.6815 Administrative...

40 CFR 35.6815 - Administrative requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Requirements for Administering A Superfund State Contract (ssc) § 35.6815 Administrative...

40 CFR 35.6815 - Administrative requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Requirements for Administering A Superfund State Contract (ssc) § 35.6815 Administrative...

40 CFR 35.6815 - Administrative requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Requirements for Administering A Superfund State Contract (ssc) § 35.6815 Administrative...

40 CFR 35.6815 - Administrative requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund Response Actions Requirements for Administering A Superfund State Contract (ssc) § 35.6815 Administrative...

76 FR 9853 - Notice of Final Federal Agency Actions on Proposed Highway in California

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-22

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Notice of Final Federal Agency Actions on Proposed Highway in California AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice... final within the meaning of 23 U.S.C. 139(l)(1). The actions relate to a proposed highway project...

Corrective Action Decision Document for Corrective Action Unit 204: Storage Bunkers, Nevada Test Site, Nevada: Revision 0, Including Errata Sheet

DOE Office of Scientific and Technical Information (OSTI.GOV)

U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office

2004-04-01

This Corrective Action Decision Document identifies the U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office's corrective action alternative recommendation for each of the corrective action sites (CASs) within Corrective Action Unit (CAU) 204: Storage Bunkers, Nevada Test Site (NTS), Nevada, under the Federal Facility Agreement and Consent Order. An evaluation of analytical data from the corrective action investigation, review of current and future operations at each CAS, and a detailed comparative analysis of potential corrective action alternatives were used to determine the appropriate corrective action for each CAS. There are six CASs in CAU 204, which aremore » all located between Areas 1, 2, 3, and 5 on the NTS. The No Further Action alternative was recommended for CASs 01-34-01, 02-34-01, 03-34-01, and 05-99-02; and a Closure in Place with Administrative Controls recommendation was the preferred corrective action for CASs 05-18-02 and 05-33-01. These alternatives were judged to meet all requirements for the technical components evaluated as well as applicable state and federal regulations for closure of the sites and will eliminate potential future exposure pathways to the contaminated media at CAU 204.« less

77 FR 64794 - Membership of the Economic Development Administration Performance Review Board

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-23

... DEPARTMENT OF COMMERCE Economic Development Administration Membership of the Economic Development Administration Performance Review Board AGENCY: Economic Development Administration, Department of Commerce. ACTION: Notice of Membership on the Economic Development Administration's Performance Review Board...

75 FR 63813 - Membership of the Economic Development Administration Performance Review Board

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-18

... DEPARTMENT OF COMMERCE Economic Development Administration Membership of the Economic Development Administration Performance Review Board AGENCY: Economic Development Administration, Department of Commerce. ACTION: Notice of membership on the Economic Development Administration's Performance Review Board...

21 CFR 812.30 - FDA action on applications.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 8 2012-04-01 2012-04-01 false FDA action on applications. 812.30 Section 812.30...) MEDICAL DEVICES INVESTIGATIONAL DEVICE EXEMPTIONS Application and Administrative Action § 812.30 FDA action on applications. (a) Approval or disapproval. FDA will notify the sponsor in writing of the date...

21 CFR 812.30 - FDA action on applications.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 8 2011-04-01 2011-04-01 false FDA action on applications. 812.30 Section 812.30...) MEDICAL DEVICES INVESTIGATIONAL DEVICE EXEMPTIONS Application and Administrative Action § 812.30 FDA action on applications. (a) Approval or disapproval. FDA will notify the sponsor in writing of the date...

21 CFR 812.30 - FDA action on applications.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 8 2014-04-01 2014-04-01 false FDA action on applications. 812.30 Section 812.30...) MEDICAL DEVICES INVESTIGATIONAL DEVICE EXEMPTIONS Application and Administrative Action § 812.30 FDA action on applications. (a) Approval or disapproval. FDA will notify the sponsor in writing of the date...

21 CFR 812.30 - FDA action on applications.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 8 2013-04-01 2013-04-01 false FDA action on applications. 812.30 Section 812.30...) MEDICAL DEVICES INVESTIGATIONAL DEVICE EXEMPTIONS Application and Administrative Action § 812.30 FDA action on applications. (a) Approval or disapproval. FDA will notify the sponsor in writing of the date...

21 CFR 812.30 - FDA action on applications.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false FDA action on applications. 812.30 Section 812.30...) MEDICAL DEVICES INVESTIGATIONAL DEVICE EXEMPTIONS Application and Administrative Action § 812.30 FDA action on applications. (a) Approval or disapproval. FDA will notify the sponsor in writing of the date...

49 CFR 222.57 - Can parties seek review of the Associate Administrator's actions?

Code of Federal Regulations, 2010 CFR

2010-10-01

..., the State agency responsible for grade crossing safety, the State agency responsible for highway and road safety, and the Associate Administrator. Unless the Administrator specifically provides otherwise... additional safety measures, by filing a petition for reconsideration with the Associate Administrator. The...

49 CFR 222.57 - Can parties seek review of the Associate Administrator's actions?

Code of Federal Regulations, 2011 CFR

2011-10-01

..., the State agency responsible for grade crossing safety, the State agency responsible for highway and road safety, and the Associate Administrator. Unless the Administrator specifically provides otherwise... additional safety measures, by filing a petition for reconsideration with the Associate Administrator. The...

A Case of Severe, Prolonged, Refractory Hypophosphatemia After Zoledronic Acid Administration.

PubMed

Clark, Sarah L; Nystrom, Erin M

2016-04-01

Zoledronic acid (ZA) administration has been associated with electrolyte abnormalities, including hypocalcemia, hypomagnesemia, hypokalemia, and hypophosphatemia. We describe a case of severe, refractory hypophosphatemia in a patient who received ZA for hypercalcemia of malignancy (HCM). Little data are available that describe the incidence or degree of severity of hypophosphatemia that can occur following ZA administration. In addition, no formal recommendations exist to guide monitoring for or management of electrolyte derangements in the setting of bisphosphonate use. Our patient required daily, high-dose phosphorus replacement beginning day 4 following ZA administration. The average daily dose of phosphorus, including both intravenous and enteral administration, was highest in the first 2 weeks after ZA, averaging 77 mmol/d days 4 through 15, and does not include sources of phosphorus from the patient's nutrition support. Despite this high amount of supplementation, which was well beyond what meets normal daily requirements and the amount expected to treat "usual" hypophosphatemia, the patient did not achieve sustained normal serum phosphorus levels for over 30 days after ZA. ZA is a favorable option for treating HCM because of its longer duration of action, potent serum calcium-lowering effects, and favorable safety profile. The risk of hypophosphatemia with ZA use is reviewed. © The Author(s) 2016.

9 CFR 4.10 - Summary action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Summary action. 4.10 Section 4.10 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL... Practice § 4.10 Summary action. (a) In any situation where the Administrator has reason to believe that any...

44 CFR 7.949 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2011 CFR

2011-10-01

... remedies. 7.949 Section 7.949 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... Investigation, Conciliation, and Enforcement Procedures § 7.949 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

44 CFR 7.949 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2010 CFR

2010-10-01

... remedies. 7.949 Section 7.949 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... Investigation, Conciliation, and Enforcement Procedures § 7.949 Exhaustion of administrative remedies. (a) A complainant may file a civil action following the exhaustion of administrative remedies under the Act...

78 FR 64595 - Notice of Final Federal Agency Actions on Proposed Highway in Illinois

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-29

... DEPARTMENT OF TRANSPORTATION Federal Highway Administration Notice of Final Federal Agency Actions on Proposed Highway in Illinois AGENCY: Federal Highway Administration (FHWA), DOT. ACTION: Notice of... Sec. 139(l)(1). The actions relate to a proposed highway project, Circle Interchange, I-90/I-94 and I...

Corrective Action Decision Document/Closure Report for Corrective Action Unit 567: Miscellaneous Soil Sites - Nevada National Security Site, Nevada

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matthews, Patrick

2014-12-01

This Corrective Action Decision Document/Closure Report presents information supporting the closure of Corrective Action Unit (CAU) 567: Miscellaneous Soil Sites, Nevada National Security Site, Nevada. The purpose of this Corrective Action Decision Document/Closure Report is to provide justification and documentation supporting the recommendation that no further corrective action is needed for CAU 567 based on the implementation of the corrective actions. The corrective actions implemented at CAU 567 were developed based on an evaluation of analytical data from the CAI, the assumed presence of COCs at specific locations, and the detailed and comparative analysis of the CAAs. The CAAs weremore » selected on technical merit focusing on performance, reliability, feasibility, safety, and cost. The implemented corrective actions meet all requirements for the technical components evaluated. The CAAs meet all applicable federal and state regulations for closure of the site. Based on the implementation of these corrective actions, the DOE, National Nuclear Security Administration Nevada Field Office provides the following recommendations: • No further corrective actions are necessary for CAU 567. • The Nevada Division of Environmental Protection issue a Notice of Completion to the DOE, National Nuclear Security Administration Nevada Field Office for closure of CAU 567. • CAU 567 be moved from Appendix III to Appendix IV of the FFACO.« less

40 CFR 300.800 - Establishment of an administrative record.

Code of Federal Regulations, 2011 CFR

2011-07-01

... POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.800 Establishment of... agency for a federal facility. (3) If EPA is involved in the selection of the response action at a... record that contains the documents that form the basis for the selection of a response action. The lead...

40 CFR 300.800 - Establishment of an administrative record.

Code of Federal Regulations, 2010 CFR

2010-07-01

... POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.800 Establishment of... agency for a federal facility. (3) If EPA is involved in the selection of the response action at a... record that contains the documents that form the basis for the selection of a response action. The lead...

40 CFR 300.800 - Establishment of an administrative record.

Code of Federal Regulations, 2014 CFR

2014-07-01

... POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.800 Establishment of... agency for a federal facility. (3) If EPA is involved in the selection of the response action at a... record that contains the documents that form the basis for the selection of a response action. The lead...

40 CFR 300.800 - Establishment of an administrative record.

Code of Federal Regulations, 2012 CFR

2012-07-01

... POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.800 Establishment of... agency for a federal facility. (3) If EPA is involved in the selection of the response action at a... record that contains the documents that form the basis for the selection of a response action. The lead...

40 CFR 300.800 - Establishment of an administrative record.

Code of Federal Regulations, 2013 CFR

2013-07-01

... POLLUTION CONTINGENCY PLAN Administrative Record for Selection of Response Action § 300.800 Establishment of... agency for a federal facility. (3) If EPA is involved in the selection of the response action at a... record that contains the documents that form the basis for the selection of a response action. The lead...

21 CFR 120.10 - Corrective actions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Corrective actions. 120.10 Section 120.10 Food and... actions. Whenever a deviation from a critical limit occurs, a processor shall take corrective action by... develop written corrective action plans, which become part of their HACCP plans in accordance with § 120.8...

Quality in Action: Closing the Loop

ERIC Educational Resources Information Center

Nair, Chenicheri Sid; Pawley, David; Mertova, Patricie

2010-01-01

Purpose: This paper aims to report on how an Administrative Division at a research-intensive Australian university utilised feedback data from the Learning and Growth Survey, to initiate changes. Design/methodology/approach: This paper refers to the actions taken by the Administrative Division to the results obtained from the Learning and Growth…

76 FR 55928 - Food and Drug Administration Health Professional Organizations Conference

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-09

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0002] Food and Drug Administration Health Professional Organizations Conference AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public conference. The Food and Drug Administration (FDA) is announcing a...

49 CFR 1503.607 - Administrative law judges.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 9 2012-10-01 2012-10-01 false Administrative law judges. 1503.607 Section 1503... PROCEDURES Rules of Practice in TSA Civil Penalty Actions § 1503.607 Administrative law judges. (a) Powers of...) Administer oaths and affirmations. (4) Issue subpoenas authorized by law. (5) Rule on offers of proof. (6...

49 CFR 1503.607 - Administrative law judges.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 9 2010-10-01 2010-10-01 false Administrative law judges. 1503.607 Section 1503... PROCEDURES Rules of Practice in TSA Civil Penalty Actions § 1503.607 Administrative law judges. (a) Powers of...) Administer oaths and affirmations. (4) Issue subpoenas authorized by law. (5) Rule on offers of proof. (6...

Affirmative Action Guidelines.

ERIC Educational Resources Information Center

Barbarita, Juana

Clarifying guidelines are presented for use by California community college districts in interpreting Title 5 of the California Administrative Code, which requires the adoption of employee affirmative action plans, including goals and timetables to increase the number of ethnic minorities and women in district employment. Following material on the…

78 FR 67210 - Charging Standard Administrative Fees for Nonprogram-Related Information; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-08

... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA-2012-0026] Charging Standard Administrative Fees for Nonprogram-Related Information; Correction AGENCY: Social Security Administration. ACTION: Notice... Social Security Administration published a document in the Federal Register of September 18, 2013...

7 CFR 246.18 - Administrative review of State agency actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) The State agency's determination to include or exclude an infant formula manufacturer, wholesaler... WOMEN, INFANTS AND CHILDREN State Agency Provisions § 246.18 Administrative review of State agency...

5 CFR 1201.136 - Action on stay request.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Action on stay request. 1201.136 Section....136 Action on stay request. (a) Initial stay. A Special Counsel request for an initial stay of 45 days... extending a stay, the agency ordered to stay a personnel action must file evidence setting forth facts and...

44 CFR 10.12 - Pre-implementation actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Pre-implementation actions. (a) Decision-making. The Regional Administrator shall ensure that... integrated into the decision-making process. Because of the diversity of FEMA, it is not feasible to describe in this part the decision-making process for each of the various FEMA programs. Proposals and actions...

75 FR 42481 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-21

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, DOT. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws for the vessel SEAFLYER... Administration (MARAD), is authorized to grant waivers of the U.S.-build requirement of the coastwise laws under...

45 CFR 91.50 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2013 CFR

2013-10-01

... her right to bring a civil action for injunctive relief; and (3) Inform the complainant: (i) That the... recipient is found or transacts business; (ii) That a complainant prevailing in a civil action has the right... Section 91.50 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION...

45 CFR 91.50 - Exhaustion of administrative remedies.

Code of Federal Regulations, 2012 CFR

2012-10-01

... her right to bring a civil action for injunctive relief; and (3) Inform the complainant: (i) That the... recipient is found or transacts business; (ii) That a complainant prevailing in a civil action has the right... Section 91.50 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION...

12 CFR 747.22 - Consolidation and severance of actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... ADMINISTRATIVE ACTIONS, ADJUDICATIVE HEARINGS, RULES OF PRACTICE AND PROCEDURE, AND INVESTIGATIONS Uniform Rules... the motion of any party, or on the administrative law judge's own motion, the administrative law judge... involves at least one common respondent or a material common question of law or fact, unless such...

5 CFR 1305.5 - No private right of action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false No private right of action. 1305.5 Section 1305.5 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATIVE PROCEDURES RELEASE OF OFFICIAL INFORMATION, AND TESTIMONY BY OMB PERSONNEL AS WITNESSES, IN LITIGATION § 1305.5 No...

5 CFR 315.605 - Appointment of former ACTION volunteers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Appointment of former ACTION volunteers... Authorities § 315.605 Appointment of former ACTION volunteers. (a) Agency authority. An agency in the... Director of ACTION certifies as having served satisfactorily as a volunteer or volunteer leader under the...

5 CFR 315.605 - Appointment of former ACTION volunteers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Appointment of former ACTION volunteers... Authorities § 315.605 Appointment of former ACTION volunteers. (a) Agency authority. An agency in the... Director of ACTION certifies as having served satisfactorily as a volunteer or volunteer leader under the...

5 CFR 315.605 - Appointment of former ACTION volunteers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Appointment of former ACTION volunteers... Authorities § 315.605 Appointment of former ACTION volunteers. (a) Agency authority. An agency in the... Director of ACTION certifies as having served satisfactorily as a volunteer or volunteer leader under the...

5 CFR 315.605 - Appointment of former ACTION volunteers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Appointment of former ACTION volunteers... Authorities § 315.605 Appointment of former ACTION volunteers. (a) Agency authority. An agency in the... Director of ACTION certifies as having served satisfactorily as a volunteer or volunteer leader under the...

5 CFR 315.605 - Appointment of former ACTION volunteers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Appointment of former ACTION volunteers... Authorities § 315.605 Appointment of former ACTION volunteers. (a) Agency authority. An agency in the... Director of ACTION certifies as having served satisfactorily as a volunteer or volunteer leader under the...

12 CFR 747.22 - Consolidation and severance of actions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Consolidation and severance of actions. 747.22... ADMINISTRATIVE ACTIONS, ADJUDICATIVE HEARINGS, RULES OF PRACTICE AND PROCEDURE, AND INVESTIGATIONS Uniform Rules of Practice and Procedure § 747.22 Consolidation and severance of actions. (a) Consolidation. (1) On...

14 CFR 13.231 - Argument before the administrative law judge.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 1 2013-01-01 2013-01-01 false Argument before the administrative law... Actions § 13.231 Argument before the administrative law judge. (a) Arguments during the hearing. During the hearing, the administrative law judge shall give the parties a reasonable opportunity to present...

14 CFR 13.231 - Argument before the administrative law judge.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Argument before the administrative law... Actions § 13.231 Argument before the administrative law judge. (a) Arguments during the hearing. During the hearing, the administrative law judge shall give the parties a reasonable opportunity to present...

Reforming Administrator Training: Here We Go Again!

ERIC Educational Resources Information Center

Drury, William R.

1989-01-01

The National Policy Board for Educational Administration report ("Improving the Preparation of School Administrators: An Agenda for Reform") reiterates the need for program improvements for educational administrators. Obstacles to any real change occurring in the near future are pointed out. (six references) (SI)

40 CFR 35.110 - Time frame for EPA action.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Time frame for EPA action. 35.110... ASSISTANCE STATE AND LOCAL ASSISTANCE Environmental Program Grants Epa Action on Application § 35.110 Time frame for EPA action. The Regional Administrator will review a complete application and either approve...

42 CFR 93.406 - Final HHS actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues... prescribed in § 93.501, the ORI finding of research misconduct is the final HHS action on the research misconduct issues and the HHS administrative actions become final and will be implemented, except that the...

75 FR 71412 - Notice of Public Meeting of the Committee on Administration

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-23

... ADMINISTRATIVE CONFERENCE OF THE UNITED STATES Notice of Public Meeting of the Committee on Administration AGENCY: Administrative Conference of the United States. ACTION: Notice of meeting. SUMMARY: Notice is hereby given that the Administrative Conference of the United States will host a public meeting of...

45 CFR 77.3 - Conditions that may give rise to remedial actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Conditions that may give rise to remedial actions. 77.3 Section 77.3 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION REMEDIAL ACTIONS APPLICABLE TO LETTER OF CREDIT ADMINISTRATION § 77.3 Conditions that may give rise to...

45 CFR 77.3 - Conditions that may give rise to remedial actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Conditions that may give rise to remedial actions. 77.3 Section 77.3 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION REMEDIAL ACTIONS APPLICABLE TO LETTER OF CREDIT ADMINISTRATION § 77.3 Conditions that may give rise to...

75 FR 34625 - Administrative Remedy Program: Exception to Initial Filing Procedures

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-18

... Remedy Program: Exception to Initial Filing Procedures AGENCY: Bureau of Prisons, Justice. ACTION... Administrative Remedy Program to add an exception to initial filing of Administrative Remedy appeals at the institution level. The exception will state that formal administrative remedy requests regarding initial...

SOCIAL PSYCHOLOGICAL FACTORS IN KNOWLEDGE UTILIZATION AS APPLIED TO EDUCATIONAL ADMINISTRATION.

ERIC Educational Resources Information Center

SCHMUCK, RICHARD

THREE PROBLEM AREAS ARE EXPLORED IN THIS SOCIAL PSYCHOLOGICAL ANALYSIS OF RESEARCH UTILIZATION IN EDUCATIONAL ADMINISTRATION--(1) INTERPERSONAL RELATIONSHIPS BETWEEN BEHAVIORAL SCIENTISTS AND SCHOOL ADMINISTRATORS, (2) PSYCHOLOGICAL LINKAGES BETWEEN THE ADMINISTRATOR'S SCIENTIFIC KNOWLEDGE AND HIS ACTIONS, AND (3) THE LACK OF CONNECTION BETWEEN…

78 FR 18481 - Project-Level Predecisional Administrative Review Process

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-27

... Administrative Review Process AGENCY: Forest Service, USDA. ACTION: Final rule. SUMMARY: The United States... process by which the public may file objections seeking predecisional administrative review for proposed... for a predecisional objection process. Section 428 further directs the Secretary to apply these...

7 CFR 246.18 - Administrative review of State agency actions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... actions: (A) Denial of authorization based on the application of the vendor selection criteria for minimum...) Denial of authorization based on the vendor selection criteria for business integrity or for a current...)(iii)); (B) Denial of authorization based on the application of the vendor selection criteria for...

21 CFR 123.7 - Corrective actions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Corrective actions. 123.7 Section 123.7 Food and... CONSUMPTION FISH AND FISHERY PRODUCTS General Provisions § 123.7 Corrective actions. (a) Whenever a deviation from a critical limit occurs, a processor shall take corrective action either by: (1) Following a...

Additive effect of combined application of magnesium and MK-801 on analgesic action of morphine.

PubMed

Bujalska-Zadrożny, Magdalena; Duda, Kamila

2014-01-01

As previously reported, magnesium ions (Mg(2+)) administered in relatively low doses markedly potentiated opioid analgesia in neuropathic pain, in which the effectiveness of opioids is limited. Considering that Mg(2+) behaves like an N-methyl-D-aspartate receptor antagonist, the effect of this ion on the analgesic action of morphine was compared with that of MK-801. Acute pain was evoked by mechanical or thermal stimuli, whereas neuropathic hyperalgesia was induced by streptozotocin (STZ) administration. Magnesium sulphate (40 mg/kg i.p.) or MK-801 (0.05 mg/kg s.c.) administered alone did not modify the nociceptive threshold to acute stimuli or the streptozotocin hyperalgesia but significantly augmented the analgesic action of morphine (5 mg/kg i.p.). Furthermore, if these drugs (i.e. magnesium sulphate and MK-801) were applied concomitantly, a clear additive effect on the analgesic action of morphine occurred in both models of pain. Possible explanations of these observations are discussed. © 2014 S. Karger AG, Basel.

12 CFR 263.22 - Consolidation and severance of actions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Consolidation and severance of actions. (a) Consolidation. (1) On the motion of any party, or on the administrative law judge's own motion, the administrative law judge may consolidate, for some or all purposes... administrative law judge may, upon the motion of any party, sever the proceeding for separate resolution of the...

12 CFR 509.22 - Consolidation and severance of actions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Consolidation and severance of actions. (a) Consolidation. (1) On the motion of any party, or on the administrative law judge's own motion, the administrative law judge may consolidate, for some or all purposes... administrative law judge may, upon the motion of any party, sever the proceeding for separate resolution of the...

Factual and Counterfactual Action-Outcome Mappings Control Choice between Goal-Directed Actions in Rats.

PubMed

Laurent, Vincent; Balleine, Bernard W

2015-04-20

The capacity to extract causal knowledge from the environment allows us to predict future events and to use those predictions to decide on a course of action. Although evidence of such causal reasoning has long been described, recent evidence suggests that using predictive knowledge to guide decision-making in this way is predicated on reasoning about causes in two quite distinct ways: choosing an action can be based on the interaction between predictive information and the consequences of that action, or, alternatively, actions can be selected based on the consequences that they do not produce. The latter counterfactual reasoning is highly adaptive because it allows us to use information about both present and absent events to guide decision-making. Nevertheless, although there is now evidence to suggest that animals other than humans, including rats and birds, can engage in causal reasoning of one kind or another, there is currently no evidence that they use counterfactual reasoning to guide choice. To assess this question, we gave rats the opportunity to learn new action-outcome relationships, after which we probed the structure of this learning by presenting excitatory and inhibitory cues predicting that the specific outcomes of their actions would either occur or would not occur. Whereas the excitors biased choice toward the action delivering the predicted outcome, the inhibitory cues selectively elevated actions predicting the absence of the inhibited outcome, suggesting that rats encoded the counterfactual action-outcome mappings and were able to use them to guide choice. Copyright © 2015 Elsevier Ltd. All rights reserved.

Root cause analysis of serious adverse events among older patients in the Veterans Health Administration.

PubMed

Lee, Alexandra; Mills, Peter D; Neily, Julia; Hemphill, Robin R

2014-06-01

Preventable adverse events are more likely to occur among older patients because of the clinical complexity of their care. The Veterans Health Administration (VHA) National Center for Patient Safety (NCPS) stores data about serious adverse events when a root cause analysis (RCA) has been performed. A primary objective of this study was to describe the types of adverse events occurring among older patients (age > or = 65 years) in Department of Veterans Affairs (VA) hospitals. Secondary objectives were to determine the underlying reasons for the occurrence of these events and report on effective action plans that have been implemented in VA hospitals. In a retrospective, cross-sectional review, RCA reports were reviewed and outcomes reported using descriptive statistics for all VA hospitals that conducted an RCA for a serious geriatric adverse event from January 2010 to January 2011 that resulted in sustained injury or death. The search produced 325 RCA reports on VA patients (age > or = 65 years). Falls (34.8%), delays in diagnosis and/or treatment (11.7%), unexpected death (9.9%), and medication errors (9.0%) were the most commonly reported adverse events among older VA patients. Communication was the most common underlying reason for these events, representing 43.9% of reported root causes. Approximately 40% of implemented action plans were judged by local staff to be effective. The RCA process identified falls and communication as important themes in serious adverse events. Concrete actions, such as process standardization and changes to communication, were reported by teams to yield some improvement. However, fewer than half of the action plans were reported to be effective. Further research is needed to guide development and implementation of effective action plans.

76 FR 30237 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws... requirement of the coastwise laws under certain circumstances. A request for such a waiver has been received...

75 FR 54960 - Requested Administrative Waiver of the Coastwise Trade Laws

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2010-09-09

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

76 FR 35944 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-20

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws... requirement of the coastwise laws under certain circumstances. A request for such a waiver has been received...

75 FR 28101 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-19

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

76 FR 51464 - Requested Administrative Waiver of the Coastwise Trade Laws

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2011-08-18

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

76 FR 29332 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-20

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws... requirement of the coastwise laws under certain circumstances. A request for such a waiver has been received...

76 FR 6184 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-03

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

76 FR 51467 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

75 FR 9021 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-26

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws... requirement of the coastwise laws under certain circumstances. A request for such a waiver has been received...

76 FR 13701 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-14

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

75 FR 11991 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-12

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

75 FR 38865 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-06

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

76 FR 11559 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-02

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws... requirement of the coastwise laws under certain circumstances. A request for such a waiver has been received...

76 FR 30236 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

75 FR 70069 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-16

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws... requirement of the coastwise laws under certain circumstances. A request for such a waiver has been received...

76 FR 820 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-06

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

76 FR 51465 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws... requirement of the coastwise laws under certain circumstances. A request for such a waiver has been received...

76 FR 30755 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-26

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws... requirement of the coastwise laws under certain circumstances. A request for such a waiver has been received...

75 FR 14487 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-25

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

76 FR 38269 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-29

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Department of Transportation, Maritime Administration. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

75 FR 5171 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-01

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

75 FR 14486 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-25

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

75 FR 5172 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-01

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

76 FR 11561 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-02

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

76 FR 13702 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-14

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws... requirement of the coastwise laws under certain circumstances. A request for such a waiver has been received...

76 FR 51466 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-18

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

76 FR 6183 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-03

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

75 FR 6433 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-09

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws....-build requirement of the coastwise laws under certain circumstances. A request for such a waiver has...

76 FR 30235 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-24

... Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Invitation for public comments on a requested administrative waiver of the Coastwise Trade Laws... requirement of the coastwise laws under certain circumstances. A request for such a waiver has been received...

76 FR 11560 - Requested Administrative Waiver of the Coastwise Trade Laws

Federal Register 2010, 2011, 2012, 2013, 2014