Sample records for aerospace lp galp

  1. 76 FR 63823 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G280 Airplane Pilot-Compartment View...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-14

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 25 [Docket No. NM457; Notice No. 25-449-SC] Special Conditions: Gulfstream Aerospace LP (GALP) Model G280 Airplane Pilot... Gulfstream Aerospace LP (GALP) Model G280 airplane. This airplane will have a novel or unusual design feature...

  2. 76 FR 30294 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G250 Airplane Pilot Compartment View...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 25 [Docket No. NM457; Notice No. 25-11-14-SC] Special Conditions: Gulfstream Aerospace LP (GALP) Model G250 Airplane Pilot... conditions for the Gulfstream Aerospace LP (GALP) Model G250 airplane. This airplane will have a novel or...

  3. 76 FR 66660 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G280 Airplane, Operation Without Normal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-27

    ... distribution and equipment-loads-demand condition. 2. After the unrestorable loss of normal engine generator... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 25 [Docket No. FAA-2011-1172: Notice No. 25-11-17-SC] Special Conditions: Gulfstream Aerospace LP (GALP) Model G280 Airplane...

  4. 76 FR 81360 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G280 Airplane, Operation Without Normal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-28

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 25 [Docket No. FAA-2011-1172: Special Conditions No. 25-453-SC] Special Conditions: Gulfstream Aerospace LP (GALP) Model G280... is not equipped with a Ram Air Turbine (RAT) generator. The loss of all electrical power to certain...

  5. 76 FR 63822 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G280 Airplane, Limit Engine Torque Loads...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-14

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 25 [Docket No. FAA-2011-1107; Special Conditions No. 25-447-SC] Special Conditions: Gulfstream Aerospace LP (GALP) Model G280 Airplane, Limit Engine Torque Loads for Sudden Engine Stoppage AGENCY: Federal Aviation Administration (FAA...

  6. 78 FR 11567 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream G150... Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.): Amendment 39...

  7. 78 FR 47546 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-06

    ... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model... Aviation Authority of Israel (CAAI), which is the aviation authority for Israel, has issued Israeli...

  8. 76 FR 41432 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-14

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Model Galaxy, Gulfstream... Aerospace LP (Type Certificate previously held by Israel Aircraft Industries, Ltd.) Model Galaxy airplanes... Bulletin 150-27- 123, Revision 1, dated January 27, 2011. (2) For Model Galaxy and Gulfstream 200 airplanes...

  9. 76 FR 70040 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-10

    ... Aerospace LP (type certificate previously held by Israel Aircraft Industries, Ltd.) Model Galaxy and....) Model Galaxy airplanes; and Gulfstream Aerospace LP Model Gulfstream 200 airplanes; serial numbers 004... Bulletin 150-27- 123, Revision 1, dated January 27, 2011. (2) For Model Galaxy and Gulfstream 200 airplanes...

  10. 78 FR 12995 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-26

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... propose to supersede an existing airworthiness directive (AD) that applies to all Gulfstream Aerospace... information identified in this proposed AD, contact Gulfstream Aerospace Corporation, P.O. Box 2206, Mail...

  11. 77 FR 58323 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... Aerospace LP (Type Certificate Previously Held by Israel Aircraft Industries, Ltd.) Airplanes AGENCY... Previously Held by Israel Aircraft Industries, Ltd.) Model Gulfstream G150 airplanes. This proposed AD was.... Discussion The Civil Aviation Authority of Israel (CAAI), which is the aviation authority for Israel, has...

  12. 75 FR 36296 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ... Manual to prohibit deploying the air brakes above the stated speed. You may obtain further information by... SPEED 360 KIAS/0.79 M i NOTE During emergency, air brakes may be used at speeds above 0.79 M i. '' Note... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft...

  13. 75 FR 57844 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... inserting a copy of this AD into the AFM. ``MAXIMUM AIR BRAKES OPERATION/EXTENDED SPEED 360 KIAS/0.79 Mi NOTE During emergency, air brakes may be used at speeds above 0.79 M i. '' Note 1: When a statement... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft...

  14. 77 FR 32069 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... Information Gulfstream Aerospace LP has issued Service Bulletin 200-32-389, Revision 1, dated October 27, 2011... Bulletin 200-32-389, Revision 1, dated October 27, 2011. (1) If the length of the pins is within the limits specified in Gulfstream Service Bulletin 200-32-389, Revision 1, dated October 27, 2011, before further...

  15. Galanin-like peptide (GALP) is a hypothalamic regulator of energy homeostasis and reproduction.

    PubMed

    Lawrence, Catherine; Fraley, Gregory S

    2011-01-01

    Galanin-like peptide (GALP) was discovered in 1999 in the porcine hypothalamus and was found to be a 60 amino acid neuropeptide. GALP shares sequence homology to galanin (1-13) in position 9-21 and can bind to, as well as activate, the three galanin receptor subtypes (GalR1-3). GALP-expressing cells are limited, and are mainly found in the arcuate nucleus of the hypothalamus (ARC) and the posterior pituitary. GALP-positive neurons in the ARC project to several brain regions where they appear to make contact with multiple neuromodulators. These neuromodulators are involved in the regulation of energy homeostasis and reproduction, anatomical evidence that suggests a role for GALP in these physiological functions. In support of this idea, GALP gene expression is regulated by several factors that reflect metabolic state including the metabolic hormones leptin and insulin, thyroid hormones, and blood glucose. Considerable evidence now exists to support the hypothesis that GALP has a role in the regulation of energy homeostasis and reproduction; and, that GALP's role may be independent of the known galanin receptors. In this review, we (1) provide an overview of the distribution of GALP, and discuss the potential relationship between GALP and other neuromodulators of energy homeostasis and reproduction, (2) discuss the metabolic factors that regulate GALP expression, (3) review the evidence for the role of GALP in energy homeostasis and reproduction, (4) discuss the potential downstream mediators and mechanisms underlying GALP's effects, and (5) discuss the possibility that GALP may mediate its effects via an as yet unidentified GALP-specific receptor. Copyright © 2010 Elsevier Inc. All rights reserved.

  16. Galanin-like Peptide (GALP) is a Hypothalamic Regulator of Energy Homeostasis and Reproduction

    PubMed Central

    Lawrence, Catherine; Fraley, Gregory S.

    2010-01-01

    Galanin-like peptide (GALP) was discovered in 1999 in the porcine hypothalamus and was found to be a 60 amino-acid neuropeptide. GALP shares sequence homology to galanin (1–13) in position 9–21 and can bind to, as well as activate, the three galanin receptor subtypes (GalR1-3). GALP-expressing cells are limited, and are mainly found in the arcuate nucleus of the hypothalamus (ARC) and the posterior pituitary. GALP-positive neurons in the ARC project to several brain regions where they appear to make contact with multiple neuromodulators. These neuromodulators are involved in the regulation of energy homeostasis and reproduction, anatomical evidence that suggests a role for GALP in these physiological functions. In support of this idea, GALP gene expression is regulated by several factors that reflect metabolic state including the metabolic hormones leptin and insulin, thyroid hormones, and blood glucose. Considerable evidence now exists to support the hypothesis that GALP has a role in the regulation of energy homeostasis and reproduction; and, that GALP’s role may be independent of the known galanin receptors. In this review we (1) provide an overview of the distribution of GALP, and discuss the potential relationship between GALP and other neuromodulators of energy homeostasis and reproduction, (2) discuss the metabolic factors that regulate GALP expression, (3) review the evidence for the role of GALP in energy homeostasis and reproduction, (4) discuss the potential downstream mediators and mechanisms underlying GALP’s effects, and (5) discuss the possibility that GALP may mediate it’s effects via an as yet unidentified GALP-specific receptor. PMID:20558195

  17. Anti-obesity effect of intranasal administration of galanin-like peptide (GALP) in obese mice

    PubMed Central

    Kageyama, Haruaki; Shiba, Kanako; Hirako, Satoshi; Wada, Nobuhiro; Yamanaka, Satoru; Nogi, Yukinori; Takenoya, Fumiko; Nonaka, Naoko; Hirano, Tsutomu; Inoue, Shuji; Shioda, Seiji

    2016-01-01

    Galanin-like peptide (GALP) has an anti-obesity effect in rats and mice. It has been reported that the uptake of GALP by the brain is higher after intranasal administration than with intravenous injection. This study therefore aimed to clarify the effect of intranasal administration of GALP on the feeding behavior of lean and obese mice. Autoradiography revealed the presence of 125I-GALP in the olfactory bulb and the brain microcirculation. The body weights of ob/ob mice gradually increased during vehicle treatment, but remained unchanged in response to repeated intranasal administration of GALP, with both ob/ob and diet-induced obese mice displaying significantly decreased food intake, water intake and locomotor activity when treated with GALP. These results suggest that intranasal administration is an effective route whereby GALP can exert its effect as an anti-obesity drug. PMID:27323911

  18. Modifying glycyrrhetinic acid liposomes with liver-targeting ligand of galactosylated derivative: preparation and evaluations

    PubMed Central

    Cheng, Yi; Gao, Youheng; Zheng, Pinjing; Li, Chuangnan; Tong, Yidan; Li, Zhao; Luo, Wenhui; Chen, Zhao

    2017-01-01

    In this study, novel glycyrrhetinic acid (GA) liposomes modified with a liver-targeting galactosylated derivative ligand (Gal) were prepared using a film-dispersion method. To characterize the samples, particle size, zeta potential, drug loading, and encapsulation efficiency were performed. Moreover, plasma and tissues were pre-treated by liquid-liquid extraction and analyzed by high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). The results showed that the mean residence times (MRTs) and the area under the curve (AUC) of GA liposomes with Gal (Gal-GA-LP), and GA liposomes (GA-LP) were higher than the GA solution (GA-S) in plasma. The tissue (liver) distribution of Gal-GA-LP was significantly different in contrast to GA-LP. The relative intake rate (Re) of Gal-GA-LP and GA-LP in the liver was 4.752 and 2.196, respectively. The peak concentration ratio (Ce) of Gal-GA-LP and GA-LP in the liver was 2.796 and 1.083, respectively. The targeting efficiency (Te) of Gal-GA-LP and GA-LP in the liver was 48.193% and 34.718%, respectively. Taken together, the results indicate that Gal-GA-LP is an ideal complex for liver-targeting, and has great potential application in the clinical treatment of hepatic diseases. Drug loading and releasing experiments also indicated that most liposomes are spherical structures and have good dispersity under physiologic conditions, which could prolong GA release efficiency in vitro. PMID:29254224

  19. Alarin but not its alternative-splicing form, GALP (Galanin-like peptide) has antimicrobial activity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wada, Akihiro, E-mail: a-wada@nagasaki-u.ac.jp; Wong, Pooi-Fong; Hojo, Hironobu

    Highlights: • Alarin inhibits the growth of E. coli but not S. aureus. • Alarin’s potency is comparable to LL-37 in inhibiting the growth of E. coli. • Alarin can cause bacterial membrane blebbing. • Alalin does not induce hemolysis on erythrocytes. -- Abstract: Alarin is an alternative-splicing form of GALP (galanin-like peptide). It shares only 5 conserved amino acids at the N-terminal region with GALP which is involved in a diverse range of normal brain functions. This study seeks to investigate whether alarin has additional functions due to its differences from GALP. Here, we have shown using a radialmore » diffusion assay that alarin but not GALP inhibited the growth of Escherichia coli (strain ML-35). The conserved N-terminal region, however, remained essential for the antimicrobial activity of alarin as truncated peptides showed reduced killing effect. Moreover, alarin inhibited the growth of E. coli in a similar potency as human cathelicidin LL-37, a well-studied antimicrobial peptide. Electron microscopy further showed that alarin induced bacterial membrane blebbing but unlike LL-37, it did not cause hemolysis of erythrocytes. In addition, alarin is only active against the gram-negative bacteria, E. coli but not the gram-positive bacteria, Staphylococcus aureus. Thus, these data suggest that alarin has potentials as an antimicrobial and should be considered for the development in human therapeutics.« less

  20. 76 FR 9771 - SFPP, L.P.; SFPP, L.P.; SFPP, L.P.; SFPP, L.P.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    ..., L.P.; SFPP, L.P.; SFPP, L.P.; SFPP, L.P.; Notice of Filing Take notice that on February 10, 2011, the SFPP, L.P. filed with the Commission a proposal to provide refunds to shippers who were not... orders dated December 8, 2006 (SFPP, L.P., 117 FERC ] 61, 285 (2007)), December 26, 2007 (SFPP, L.P., 121...

  1. 77 FR 36123 - Special Conditions: Gulfstream Aerospace LP (GALP), Model Gulfstream G280 Airplane; Aircraft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-18

    ... architecture and connectivity capabilities of the airplane's computer systems and networks, which may allow... an association, business, labor union, etc.). DOT's complete Privacy Act Statement can be found in... or unusual design features: Digital systems architecture composed of several connected networks. The...

  2. 76 FR 35736 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G250 Airplane Automatic Power Reserve...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... novel or unusual design feature associated with go-around performance credit for use of Automatic Power... docket in person, go to the address in the ADDRESSES section of this preamble between 7:30 a.m. and 4 p.m... proposing to use the APR function of the Model G250 airplane during go-around and is requesting approach...

  3. 76 FR 25229 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G250 Airplane, Dynamic Test Requirements...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-04

    ..., Dynamic Test Requirements for Side-Facing, Single-Occupant Seats AGENCY: Federal Aviation Administration... or unusual design feature associated with dynamic test requirements for side-facing, single-occupant..., Aircraft Certification Service, 1601 Lind Avenue, SW., Renton, Washington 98057- 3356; telephone (425) 227...

  4. 76 FR 41041 - Special Conditions: Gulfstream Aerospace LP (GALP) Model G250 Airplane, Interaction of Systems...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... performance. They cannot be considered in isolation but should be included in the overall safety evaluation of.... 25.629(b)(2) are maintained. (4) Failures of the system that result in forced structural vibrations...

  5. 77 FR 38467 - Special Conditions: Gulfstream Aerospace LP (GALP), Model Gulfstream G280 Airplane; Isolation or...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ... network security vulnerabilities and increased risks potentially resulting in unsafe conditions for the... Gulfstream G280 Airplane; Isolation or Aircraft Electronic System Security Protection From Unauthorized... connectivity of the passenger service computer systems to the airplane critical systems and data networks. The...

  6. 76 FR 41045 - Special Conditions; Gulfstream Aerospace LP (GALP) Model G250 Airplane, Design Roll-Maneuver...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... with electronic flight controls as they relate to design roll-maneuver requirements. The applicable... load condition at design maneuvering speed V A , in which the cockpit roll control is returned to... neutral position. 3. At design cruising speed V C , the cockpit roll control must be moved suddenly and...

  7. 75 FR 39680 - Houston Pipe Line Company LP, Worsham-Steed Gas Storage, L.P., Energy Transfer Fuel, LP, Mid...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-12

    ... Company LP, Worsham-Steed Gas Storage, L.P., Energy Transfer Fuel, LP, Mid Continent Market Center, L.L.C... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-44-000; Docket No. PR10... the protest or intervention to the Federal Energy Regulatory Commission, 888 First Street, NE...

  8. Lp-dual affine surface area

    NASA Astrophysics Data System (ADS)

    Wei, Wang; Binwu, He

    2008-12-01

    According to the notion of Lp-affine surface area by Lutwak, in this paper, we introduce the concept of Lp-dual affine surface area. Further, we establish the affine isoperimetric inequality and the Blaschke-Santaló inequality for Lp-dual affine surface area. Besides, the dual Brunn-Minkowski inequality for Lp-dual affine surface area is presented.

  9. LP01 to LP0m mode converters using all-fiber two-stage tapers

    NASA Astrophysics Data System (ADS)

    Mellah, Hakim; Zhang, Xiupu; Shen, Dongya

    2015-11-01

    A mode converter between LP01 and LP0m modes is proposed using two stages of tapers. The first stage is formed by an adiabatically tapering a circular fiber to excite the desirable LP0m mode. The second stage is formed by inserting an inner core (tapered from both sides) with a refractive index smaller than the original core. This second stage is used to obtain low insertion loss and high extinction ratio of the desired LP0m mode. Three converters between LP01 and LP0m, m=2, 3, and 4, are designed for C-band, and simulation results show that less than 0.24, 0.54 and 0.7 dB insertion loss and higher than 15, 16, and 17.5 dB extinction ratio over the entire band were obtained for the three converters, respectively.

  10. A novel optical waveguide LP01/LP02 mode converter

    NASA Astrophysics Data System (ADS)

    Shen, Dongya; Wang, Changhui; Ma, Chuan; Mellah, Hakim; Zhang, Xiupu; Yuan, Hong; Ren, Wenping

    2018-07-01

    A novel optical waveguide LP01 /LP02 mode converter is proposed using combination of bicone structure based on the coupled-mode theory. It is composed of a cladding, a tapered core and combined bicone structure. It is found that this mode converter can have operating bandwidth of 1350-1700 nm, i.e. 350 nm, with a conversion efficiency of ∼90% (∼0.5 dB) and low crosstalk from other modes

  11. Aerospace Community. Aerospace Education I.

    ERIC Educational Resources Information Center

    Mickey, V. V.

    This book, one in the series on Aerospace Education I, emphasizes the two sides of aerospace--military aerospace and civilian aerospace. Chapter 1 includes a brief discussion on the organization of Air Force bases and missile sites in relation to their missions. Chapter 2 examines the community services provided by Air Force bases. The topics…

  12. Transverse stress induced LP 02-LP 21 modal interference of stimulated Raman scattered light in a few-mode optical fiber

    NASA Astrophysics Data System (ADS)

    Sharma, A.; Posey, R.

    1996-02-01

    Four-photon mixing followed by stimulated Raman scattering is observed in LP 02 mode in a 7.9 μm core diameter optical fiber. A localized transverse stress efficiency couples LP 02 to the LP 21 mode with a macroscopic beat length of 1.8 mm. LP 02-LP 21 modal interference is investigated by detecting the 550-590 nm SRS through a pinhole in the far field exit plane. Quantitative explanation of wavelength dependent intensity modulation results in a precise experimental determination of {∂[β 02(λ) - β 21(λ)] }/{∂λ}, for mode-propagation constants β02( λ) and β21( λ) of LP 02 and LP 21 modes respectively, as well as Δ, the relative core-cladding refractive index difference. The LP 02-LP 21 modal interference is used for sensing of temperature between 50-300°C.

  13. 77 FR 59393 - Jordan Cove Energy Project LP; Pacific Connector Gas Pipeline LP; Notice of Additional Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-27

    ...-17-000] Jordan Cove Energy Project LP; Pacific Connector Gas Pipeline LP; Notice of Additional Public..., and 11, 2012, the Federal Energy Regulatory Commission (FERC or Commission) Office of Energy Projects... additional public scoping meetings to take comments on Jordan Cove Energy Project LP's (Jordan Cove) proposed...

  14. Lp-mixed affine surface area

    NASA Astrophysics Data System (ADS)

    Wang, Weidong; Leng, Gangsong

    2007-11-01

    According to the three notions of mixed affine surface area, Lp-affine surface area and Lp-mixed affine surface area proposed by Lutwak, in this article, we give the concept of ith Lp-mixed affine surface area such that the first and second notions of Lutwak are its special cases. Further, some Lutwak's results are extended associated with this concept. Besides, applying this concept, we establish an inequality for the volumes and dual quermassintegrals of a class of star bodies.

  15. Selective excitation of LP01 and LP02 in dual-concentric cores fiber using an adiabatically tapered microstructured mode converter

    NASA Astrophysics Data System (ADS)

    Sammouda, Marwa; Taher, Aymen Belhadj; Bahloul, Faouzi; Bin, Philippe Di

    2016-09-01

    We propose to connect a single-mode fiber (SMF) to a dual-concentric cores fiber (DCCF) using an adiabatically tapered microstructured mode converter, and to evaluate the SMF LP01 mode and the DCCF LP01 and LP02 modes selective excitations performances. We theoretically and numerically study this selective excitation method by calculating the effective indices of the propagated modes, the adiabaticity criteria, the coupling loss, and the modes amplitudes along the tapered structure. This study shows that this method is able to achieve excellent selective excitations of the first two linearly polarized modes (LP01 and LP02) among the five guided modes in the DCCF with a negligible loss. The part of the LP01 and LP02 modes from the total power are 99% and 84% corresponding to 0.1 and 0.8 dB losses, respectively.

  16. 77 FR 58371 - Allegheny Hydro No. 8, L.P., Allegheny Hydro No. 9, L.P., and U.S. Bank National Association...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 3021-088] Allegheny Hydro No. 8, L.P., Allegheny Hydro No. 9, L.P., and U.S. Bank National Association Allegheny Hydro, LLC... 31, 2012, Allegheny Hydro No. 8, L.P., Allegheny Hydro No. 9, L.P., and U.S. Bank National...

  17. The Lp_3561 and Lp_3562 Enzymes Support a Functional Divergence Process in the Lipase/Esterase Toolkit from Lactobacillus plantarum

    PubMed Central

    Esteban-Torres, María; Reverón, Inés; Santamaría, Laura; Mancheño, José M.; de las Rivas, Blanca; Muñoz, Rosario

    2016-01-01

    Lactobacillus plantarum species is a good source of esterases since both lipolytic and esterase activities have been described for strains of this species. No fundamental biochemical difference exists among esterases and lipases since both share a common catalytic mechanism. L. plantarum WCFS1 possesses a protein, Lp_3561, which is 44% identical to a previously described lipase, Lp_3562. In contrast to Lp_3562, Lp_3561 was unable to degrade esters possessing a chain length higher than C4 and the triglyceride tributyrin. As in other L. plantarum esterases, the electrostatic potential surface around the active site in Lp_3561 is predicted to be basic, whereas it is essentially neutral in the Lp_3562 lipase. The fact that the genes encoding both proteins were located contiguously in the L. plantarum WCFS1 genome, suggests that they originated by tandem duplication, and therefore are paralogs as new functions have arisen during evolution. The presence of the contiguous lp_3561 and lp_3562 genes was studied among L. plantarum strains. They are located in a 8,903 bp DNA fragment that encodes proteins involved in the catabolism of sialic acid and are predicted to increase bacterial adaptability under certain growth conditions. PMID:27486450

  18. LP01 to LP11 mode convertor based on side-polished small-core single-mode fiber

    NASA Astrophysics Data System (ADS)

    Liu, Yan; Li, Yang; Li, Wei-dong

    2018-03-01

    An all-fiber LP01-LP11 mode convertor based on side-polished small-core single-mode fibers (SMFs) is numerically demonstrated. The linearly polarized incident beam in one arm experiences π shift through a fiber half waveplate, and the side-polished parts merge into an equivalent twin-core fiber (TCF) which spatially shapes the incident LP01 modes to the LP11 mode supported by the step-index few-mode fiber (FMF). Optimum conditions for the highest conversion efficiency are investigated using the beam propagation method (BPM) with an approximate efficiency as high as 96.7%. The proposed scheme can operate within a wide wavelength range from 1.3 μm to1.7 μm with overall conversion efficiency greater than 95%. The effective mode area and coupling loss are also characterized in detail by finite element method (FEM).

  19. 78 FR 22872 - TexStar Transmission, LP; TEAK Texana Transmission Company, LP; Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-17

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR13-16-001; Docket No. PR13-17-001; Not Consolidated] TexStar Transmission, LP; TEAK Texana Transmission Company, LP; Notice of Filings Take notice that on April 5, 2013, the applicants listed above submitted an amendment to the...

  20. 78 FR 25262 - TexStar Transmission, LP; TEAK Texana Transmission Company, LP; Notice of Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket Nos. PR13-16-002; PR13-17-002; Not Consolidated] TexStar Transmission, LP; TEAK Texana Transmission Company, LP; Notice of Filings Take notice that on April 23, 2013, the applicants listed above submitted an amendment to the December...

  1. The Aerospace Age. Aerospace Education I.

    ERIC Educational Resources Information Center

    Smith, J. C.

    This book is written for use only in the Air Force ROTC program and cannot be purchased on the open market. The book describes the historical development of aerospace industry. The first chapter contains a brief review of the aerospace environment and the nature of technological changes brought by the aerospace revolution. The following chapter…

  2. 78 FR 45592 - DeltaPoint Capital IV, LP;

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-29

    ... Regulations (13 CFR 107.730). DeltaPoint Capital IV, L.P. provided financing to BioMaxx, Inc., 1 Fishers Road... York), L.P., an Associate of DeltaPoint Capital IV, L.P., owns more than ten percent of BioMaxx, Inc...

  3. 77 FR 74179 - TexStar Transmission, LP; TEAK Texana Transmission Company, LP; Notice of Baseline Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR13-16-000; Docket No. PR13-17-000; Not Consolidated] TexStar Transmission, LP; TEAK Texana Transmission Company, LP; Notice of Baseline Filings Take notice that on December 6, 2012, the applicants listed above submitted a baseline...

  4. 78 FR 21491 - DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P.; Notice Seeking Exemption...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ... SMALL BUSINESS ADMINISTRATION [License No. 02/02-0662, 02/02-0661] DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that DeltaPoint Capital IV, L.P. and DeltaPoint...

  5. 76 FR 53440 - Freeport LNG Development, LP; Freeport LNG Expansion, LP; FLNG Liquefaction LLC; Notice of Intent...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PF11-2-000] Freeport LNG Development, LP; Freeport LNG Expansion, LP; FLNG Liquefaction LLC; Notice of Intent To Prepare an Environmental Assessment for the Planned Liquefaction Project, Request for Comments on Environmental Issues, and Notice of Public Scoping Meeting The...

  6. The Land Processes Distributed Active Archive Center (LP DAAC)

    USGS Publications Warehouse

    Golon, Danielle K.

    2016-10-03

    The Land Processes Distributed Active Archive Center (LP DAAC) operates as a partnership with the U.S. Geological Survey and is 1 of 12 DAACs within the National Aeronautics and Space Administration (NASA) Earth Observing System Data and Information System (EOSDIS). The LP DAAC ingests, archives, processes, and distributes NASA Earth science remote sensing data. These data are provided to the public at no charge. Data distributed by the LP DAAC provide information about Earth’s surface from daily to yearly intervals and at 15 to 5,600 meter spatial resolution. Data provided by the LP DAAC can be used to study changes in agriculture, vegetation, ecosystems, elevation, and much more. The LP DAAC provides several ways to access, process, and interact with these data. In addition, the LP DAAC is actively archiving new datasets to provide users with a variety of data to study the Earth.

  7. Aerospace Environment. Aerospace Education I.

    ERIC Educational Resources Information Center

    Savler, D. S.; Smith, J. C.

    This book is one in the series on Aerospace Education I. It briefly reviews current knowledge of the universe, the earth and its life-supporting atmosphere, and the arrangement of celestial bodies in outer space and their physical characteristics. Chapter 1 includes a brief survey of the aerospace environment. Chapters 2 and 3 examine the…

  8. Military Aerospace. Aerospace Education II.

    ERIC Educational Resources Information Center

    Smith, J. C.

    This book is a revised publication in the series on Aerospace Education II. It describes the employment of aerospace forces, their methods of operation, and some of the weapons and equipment used in combat and combat support activities. The first chapter describes some of the national objectives and policies served by the Air Force in peace and…

  9. Novel enzymatic method for assaying Lp-PLA2 in serum.

    PubMed

    Yamaura, Saki; Sakasegawa, Shin-Ichi; Koguma, Emisa; Ueda, Shigeru; Kayamori, Yuzo; Sugimori, Daisuke; Karasawa, Ken

    2018-06-01

    Measurement of lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) can be used as an adjunct to traditional cardiovascular risk factors for identifying individuals at higher risk of cardiovascular events. This can be performed by quantification of the protein concentration using an ELISA platform or by measuring Lp-PLA 2 activity using platelet-activating factor (PAF) analog as substrate. Here, an enzymatic Lp-PLA 2 activity assay method using 1-O-Hexadecyl-2-acetyl-rac-glycero-3-phosphocholine (rac C 16 PAF) was developed. The newly revealed substrate specificity of lysoplasmalogen-specific phospholipase D (lysophospholipase D (LysoPLD)) was exploited. Lp-PLA 2 hydrolyzes 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C 16 PAF) to 1-O-Hexadecyl-2-hydroxy-sn-glycero-3-phosphocholine (LysoPAF). LysoPLD acted on LysoPAF, and the hydrolytically released choline was detected by choline oxidase. Regression analysis of Lp-PLA 2 activity measured by the enzymatic Lp-PLA 2 activity assay vs. two chemical Lp-PLA 2 activity assays, i.e. LpPLA 2 FS and PLAC® test, and ELISA, gave the following correlation coefficients: 0.990, 0.893 and 0.785, respectively (n = 30). Advantages of this enzymatic Lp-PLA 2 activity assay compared with chemical Lp-PLA 2 methods include the following; (i) only requires two reagents enabling a simple two-point linear calibration method with one calibrator (ii) no need for inhibitors of esterase-like activity in serum. Copyright © 2018 Elsevier B.V. All rights reserved.

  10. 77 FR 73637 - Alliance Pipeline L.P.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-11

    ... Pipeline L.P.; Notice of Application Take notice that on November 26, 2012, Alliance Pipeline L.P..., Manager, Regulatory Affairs, Alliance Pipeline Ltd. on behalf of Alliance Pipeline L.P., 800, 605-5 Ave...] BILLING CODE 6717-01-P ...

  11. 77 FR 7572 - Alliance Pipeline L.P.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-13

    ...] Alliance Pipeline L.P.; Notice of Application Take notice that on January 25, 2012, Alliance Pipeline L.P... Pipeline Inc., Managing General Partner of Alliance Pipeline L.P., 800, 605--5 Ave. SW., Calgary, Alberta...; 8:45 am] BILLING CODE 6717-01-P ...

  12. Women in Aerospace Awards

    NASA Image and Video Library

    2010-10-26

    NASA Langley Aerospace Engineer Jill Lynette Hanna Prince receives the Women in Aerospace Achievement in Aerospace award from North Carolina State Professor Robert Tolson during the Women in Aerospace organization's annual awards ceremony and banquet held at the Ritz-Carlton Hotel in Arlington, VA on Tuesday, Oct. 26, 2010. Four current NASA leaders and one retiree were recognized for their work by Women in Aerospace. The event celebrates women's professional excellence in aerospace and honors women who have made outstanding contributions to the aerospace community. Photo Credit: (NASA/Bill Ingalls)

  13. Recent progress in making protein microarray through BioLP

    NASA Astrophysics Data System (ADS)

    Yang, Rusong; Wei, Lian; Feng, Ying; Li, Xiujian; Zhou, Quan

    2017-02-01

    Biological laser printing (BioLP) is a promising biomaterial printing technique. It has the advantage of high resolution, high bioactivity, high printing frequency and small transported liquid amount. In this paper, a set of BioLP device is design and made, and protein microarrays are printed by this device. It's found that both laser intensity and fluid layer thickness have an influence on the microarrays acquired. Besides, two kinds of the fluid layer coating methods are compared, and the results show that blade coating method is better than well-coating method in BioLP. A microarray of 0.76pL protein microarray and a "NUDT" patterned microarray are printed to testify the printing ability of BioLP.

  14. 78 FR 21491 - DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P.; Notice Seeking Exemption...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ... Small Business Investment Act of 1958, as amended (``the Act''), in connection with the financing of a... SMALL BUSINESS ADMINISTRATION [License No. 02/02-0662, 02/02-0661] DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P.; Notice Seeking Exemption Under Section 312 of the Small Business...

  15. Aerospace Medicine

    NASA Technical Reports Server (NTRS)

    Michaud, Vince

    2015-01-01

    NASA Aerospace Medicine overview - Aerospace Medicine is that specialty area of medicine concerned with the determination and maintenance of the health, safety, and performance of those who fly in the air or in space.

  16. Aerospace Meteorology Lessons Learned Relative to Aerospace Vehicle Design and Operations

    NASA Technical Reports Server (NTRS)

    Vaughan, William W.; Anderson, B. Jeffrey

    2004-01-01

    Aerospace Meteorology came into being in the 1950s as the development of rockets for military and civilian usage grew in the United States. The term was coined to identify those involved in the development of natural environment models, design/operational requirements, and environment measurement systems to support the needs of aerospace vehicles, both launch vehicles and spacecraft. It encompassed the atmospheric environment of the Earth, including Earth orbit environments. Several groups within the United States were active in this area, including the Department of Defense, National Aeronautics and Space Administration, and a few of the aerospace industry groups. Some aerospace meteorology efforts were similar to those being undertaken relative to aviation interests. As part of the aerospace meteorology activities a number of lessons learned resulted that produced follow on efforts which benefited from these experiences, thus leading to the rather efficient and technologically current descriptions of terrestrial environment design requirements, prelaunch monitoring systems, and forecast capabilities available to support the development and operations of aerospace vehicles.

  17. Elevated serum β₂-GPI-Lp(a) complexes levels in children with nephrotic syndrome.

    PubMed

    Zhang, Chunni; Luo, Yang; Huang, Zhongwei; Xia, Zhengkun; Cai, Xiaoyi; Yang, Yuhua; Niu, Dongmei; Wang, Junjun

    2012-10-09

    The complexes of β₂-glycoprotein I (β₂-GPI) with lipoprotein(a) [β₂-GPI-Lp(a)] exist in human circulation and are increased in serum from patients with some autoimmune diseases. This study aims to investigate the concentration of β₂-GPI-Lp(a) in serum of children with idiopathic nephrotic syndrome (NS) and its relationship with serum lipids, oxidized lipoprotein and renal function parameters to explore the potential of the complexes as an additional marker for evaluating pediatric NS. Serum concentrations of β₂-GPI-Lp(a) complexes and oxidized Lp(a) [ox-Lp(a)] were measured by "Sandwich" ELISAs in 80 NS children and 82 age/sex-matched healthy controls. The levels of serum lipids and kidney parameters were also determined. Multivariate logistic regression analysis was performed to identify correlate of β₂-GPI-Lp(a) and NS. The serum concentrations of β₂-GPI-Lp(a) complexes in children with NS were significantly higher than those in controls (median 0.95 U/ml vs 0.28 U/ml, P<0.0001). Ox-Lp(a) levels were also markedly elevated (median 14.55 mg/l vs 2.60 mg/l, P<0.0001] in NS children. The concentrations of β₂-GPI-Lp(a) were positively correlated with ox-Lp(a) (r=0.246, P=0.028), but not with Lp(a) level, and the concentrations of ox-Lp(a) were positively related with Lp(a) (r=0.301, P=0.007) in NS children. Multivariate logistic regression analysis identified a positive association between NS and β₂-GPI-Lp(a) (OR=13.694, 95% CI 6.400-29.299, P<0.0001), after adjusting for kidney function parameters, serum lipids and ox-Lp(a). Elevated β₂-GPI-Lp(a) level was an independent and significant risk factor for pediatric NS and, enhanced Lp(a) oxidation partly contributes to the formation of β₂-GPI-Lp(a) complexes. Copyright © 2012 Elsevier B.V. All rights reserved.

  18. Women in Aerospace Awards

    NASA Image and Video Library

    2010-10-26

    NASA Headquarters Program Planning Specialist Beth Beck speaks after being given the Women in Aerospace's Aerospace Awareness Award at the organization's annual awards ceremony and banquet held at the Ritz-Carlton Hotel in Arlington, VA on Tuesday, Oct. 26, 2010. Four current NASA leaders and one retiree were recognized for their work by Women in Aerospace. The event celebrates women's professional excellence in aerospace and honors women who have made outstanding contributions to the aerospace community. Photo Credit: (NASA/Bill Ingalls)

  19. PuLP/XtraPuLP : Partitioning Tools for Extreme-Scale Graphs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Slota, George M; Rajamanickam, Sivasankaran; Madduri, Kamesh

    2017-09-21

    PuLP/XtraPulp is software for partitioning graphs from several real-world problems. Graphs occur in several places in real world from road networks, social networks and scientific simulations. For efficient parallel processing these graphs have to be partitioned (split) with respect to metrics such as computation and communication costs. Our software allows such partitioning for massive graphs.

  20. CORN, LP Goldfield Approval

    EPA Pesticide Factsheets

    This November 19, 2015 letter from EPA approves the petition from CORN, LP, Goldfield facility, regarding non-grandfathered ethanol produced through a dry mill process, qualifying under the Clean Air Act for renewable fuel (D-code 6) RINs under the RFS pro

  1. 78 FR 16846 - Notice of Application; Equitrans, L.P.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-19

    ... Application; Equitrans, L.P. Take notice that on March 1, 2013, Equitrans, L.P. (Equitrans), 625 Liberty... (toll free). For TTY, call (202) 502-8659. Comment date: 5:00 p.m. Eastern Time on April 2, 2013. Dated... 6717-01-P ...

  2. Aerospace Education - An Overview

    ERIC Educational Resources Information Center

    Journal of Aerospace Education, 1975

    1975-01-01

    Discusses the surge of interest throughout the country in aerospace education and discusses what aerospace education is, the implications in career education and the relevance of aerospace education in the curriculum. (BR)

  3. Basic Aerospace Education Library

    ERIC Educational Resources Information Center

    Journal of Aerospace Education, 1975

    1975-01-01

    Lists the most significant resource items on aerospace education which are presently available. Includes source books, bibliographies, directories, encyclopedias, dictionaries, audiovisuals, curriculum/planning guides, aerospace statistics, aerospace education statistics and newsletters. (BR)

  4. Complications after LP related to needle type: pencil-point versus Quincke.

    PubMed

    Aamodt, A; Vedeler, C

    2001-06-01

    We studied the incidence of complications after diagnostic lumbar puncture (LP) related to needle type. A 5 months' observational study of routine diagnostic LP in 83 patients was conducted. Significantly more headache was observed after LP using thicker cutting needles (20G Quincke) compared with thinner cutting or non-cutting needles (22G Quincke or pencil-point). No significant difference in complications after LP was found between the 22G Quincke and pencil-point needles. The size of the needle and not the needle shape seems to be the main determinant for post-dural puncture headache (PDPH).

  5. 75 FR 38514 - Application to Export Electric Energy; Brookfield Energy Marketing LP

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... Energy Marketing LP AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Brookfield Energy Marketing LP (BEM LP) has applied for authority to transmit electric... surplus energy purchased from electric utilities, Federal power marketing agencies and other entities...

  6. 76 FR 9341 - Equitrans, L.P.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-17

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket Nos. CP11-68-000; PF10-19-000] Equitrans, L.P.; Notice of Application Take notice that on January 27, 2011, Equitrans, L.P. (``Equitrans''), having its principal place of business at 625 Liberty Avenue, Suite 1700, Pittsburgh, Pennsylvania 15222...

  7. COS LP4 FUV Target Acquisition Enabling and Verification

    NASA Astrophysics Data System (ADS)

    Penton, Steven V.

    2016-10-01

    This LP4 program is designed to verify the ability of the LV0058/LV0059 COS FSW to place an isolated point source at the center of the PSA, using FUV dispersed light target acquisition (TA) for COS (LP4-TA-COS). Tests will be performed for all 3 FUV TA modes (ACQ/SEARCH, ACQ/PEAKD, and ACQ/PEAKXD). It is sufficient to test ACQ/SEARCH and ACQ/PEAKD with only one grating, but all three FUV gratings need to be tested for the new (as of LV0054) ACQ/PEAKXD with NUM_POS>1 (also known internally, and in the spt files, as OPMODE=ACQ/PEAKD(XD) at the Fourth Lifetime Position (LP4). This program is modeled after the LP2 and LP3 versions of this program; 12797 and 13636.This program has specific visits to test each portion of the FUV spectroscopic TA process. Visits 01-05 will use the target AV18, while Visit 06 will observe (WD1657+343). Both targets are visible year round. For the LP4 enabling, several improvements to APT, the ground system, and the flight software (FSW) have greatly simplified the enabling process. There are now no non-standard exposures, or special commanding, in this program.Specifically; 1) We now use the LIFETIME-POS = LP4 functionality in APT & FSW to specify the LP. The old procedure of using LIFETIME-POS ="ALTERNATE" has been removed. FUV LPs are now called out by number (e.g., LP4). 2) We will be using the new NUM_POS > 1 PEAKXD algorithm at LP4 due to large geometric distortions (GD) at the "Y" detector positions of LP4. FUVA is particularly affected by GD rendering the old PEAKXD algorithm unable to center a target to the required XD accuracy at LP4. 3) Numerous FSW Patchable constants that were essential for PEAKXD operations at previous LPs are no longer required. These are the WCA-to-PSA offsets and XD plate-scales. Like PEAKD, the NUM_POS > 1 PEAKXD requires no patchable constant updates. At previous LPs, numerous updates to the patchable constants were required, this is not necessary for LP4 TA enabling.Prior to the submission of this

  8. Women in Aerospace Awards

    NASA Image and Video Library

    2010-10-26

    NASA Deputy Administrator Lori Garver speaks after being given the Women in Aerospace's Outstanding Member Award at the organization's annual awards ceremony and banquet held at the Ritz-Carlton Hotel in Arlington, VA on Tuesday, Oct. 26, 2010. Four current NASA leaders and one retiree were recognized for their work by Women in Aerospace. The event celebrates women's professional excellence in aerospace and honors women who have made outstanding contributions to the aerospace community. Photo Credit: (NASA/Bill Ingalls)

  9. Women in Aerospace Awards

    NASA Image and Video Library

    2010-10-26

    NASA's Langley Research Center Lesa Roe speaks after being given the Women in Aerospace's Leadership Award at the organization's annual awards ceremony and banquet held at the Ritz-Carlton Hotel in Arlington, VA on Tuesday, Oct. 26, 2010. Four current NASA leaders and one retiree were recognized for their work by Women in Aerospace. The event celebrates women's professional excellence in aerospace and honors women who have made outstanding contributions to the aerospace community. Photo Credit: (NASA/Bill Ingalls)

  10. Glycyrrhetinic Acid Liposomes Containing Mannose-Diester Lauric Diacid-Cholesterol Conjugate Synthesized by Lipase-Catalytic Acylation for Liver-Specific Delivery.

    PubMed

    Chen, Jing; Chen, Yuchao; Cheng, Yi; Gao, Youheng

    2017-09-24

    Mannose-diester lauric diacid-cholesterol (Man-DLD-Chol), as a liposomal target ligand, was synthesized by lipase catalyzed in a non-aqueous medium. Its chemical structure was confirmed by mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy. Glycyrrhetinic acid (GA) liposomes containing Man-DLD-Chol (Man-DLD-Chol-GA-Lp) were prepared by the film-dispersion method. We evaluated the characterizations of liposomes, drug-release in vitro, the hemolytic test, cellular uptake, pharmacokinetics, and the tissue distributions. The cellular uptake in vitro suggested that the uptake of Man-DLD-Chol-modified liposomes was significantly higher than that of unmodified liposomes in HepG2 cells. Pharmacokinetic parameters indicated that Man-DLD-Chol-GA-Lp was eliminated more rapidly than GA-Lp. In tissue distributions, the targeting efficiency (Te) of Man-DLD-Chol-GA-Lp on liver was 54.67%, relative targeting efficiency (R Te ) was 3.39, relative uptake rate (Re) was 4.78, and peak concentration ratio (Ce) was 3.46. All these results supported the hypothesis that Man-DLD-Chol would be an efficient liposomal carrier, and demonstrated that Man-DLD-Chol-GA-Lp has potential as a drug delivery for liver-targeting therapy.

  11. Women in Aerospace Awards

    NASA Image and Video Library

    2010-10-26

    NASA's Associate Administrator of the Science Mission Directorate Dr. Edward J. Weiler presents the Women in Aerospace's Lifetime Achievement Award to retired NASA chief astronomer Nancy Grace Roman at the organization's annual awards ceremony and banquet held at the Ritz-Carlton Hotel in Arlington, VA on Tuesday, Oct. 26, 2010. Four current NASA leaders and one retiree were recognized for their work by Women in Aerospace. The event celebrates women's professional excellence in aerospace and honors women who have made outstanding contributions to the aerospace community. Photo Credit: (NASA/Bill Ingalls)

  12. 76 FR 7833 - Texas Eastern Transmission, LP; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ...] Texas Eastern Transmission, LP; Notice of Application Take notice that on January 25, 2011, Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056, filed in the above... TEAM 2012 Project. Specifically, Texas Eastern requests: (i) Authorization under NGA sections 7(b) and...

  13. 76 FR 49760 - Texas Eastern Transmission, LP; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-11

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP11-524-000] Texas Eastern Transmission, LP; Notice of Application Take notice that on July 29, 2011, Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056-5310, filed with the Federal Energy...

  14. 77 FR 20015 - Texas Eastern Transmission, LP; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-03

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP12-88-000] Texas Eastern Transmission, LP; Notice of Application Take notice that on March 19, 2012, Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056-5310, filed an application in Docket No...

  15. 77 FR 12045 - Texas Eastern Transmission, LP; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-28

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP12-68-000] Texas Eastern Transmission, LP; Notice of Application Take notice that on February 16, 2012, Texas Eastern Transmission, LP (Texas Eastern), PO Box 1642, Houston, Texas 77056 filed an application in the above referenced docket...

  16. 78 FR 43874 - Texas Eastern Transmission, LP; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-22

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP13-514-000] Texas Eastern Transmission, LP; Notice of Application On July 2, 2013, Texas Eastern Transmission, LP (Texas Eastern) filed... natural gas facilities no longer in service. As described more fully in the Application, Texas Eastern...

  17. 76 FR 38381 - Texas Eastern Transmission, LP; Notice of Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-30

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP11-67-001] Texas Eastern Transmission, LP; Notice of Amendment Take notice that on June 13, 2011, Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056, filed in the above referenced docket an amendment...

  18. 78 FR 32294 - DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P., License No. 02/02-0662,02/02...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    ... Small Business Investment Act of 1958, as amended (``the Act''), in connection with the financing of a... SMALL BUSINESS ADMINISTRATION DeltaPoint Capital IV, L.P., DeltaPoint Capital IV (New York), L.P., License No. 02/02-0662,02/02-0661; Notice Seeking Exemption Under Section 312 of the Small Business...

  19. 77 FR 26534 - Texas Eastern Transmission, LP; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP12-164-000] Texas Eastern Transmission, LP; Notice of Application Take notice that on April 19, 2012, Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056, filed in Docket No. CP12-164-000, a request...

  20. 78 FR 66352 - Texas Eastern Transmission, LP; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP14-9-000] Texas Eastern Transmission, LP; Notice of Application Take notice that on October 17, 2013, Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056, filed an application in Docket No. CP14-9...

  1. International Access to Aerospace Information.

    DTIC Science & Technology

    1980-04-01

    data that belong into the category ’reproducible" belong here into the category ’conditions controlled by man" " non reproducible data’ belong into the...SESSION IV - NON -LITERATURE DATA IN AEROSPACE RESEARCH AND DEVELOPMENT THE NUMERIC AEROSPACE DATA: PROBLEMS OF EVALUATION, HANDLING AND DISSEMINATION...34. Sessions III and IV, held on 18 October, were entitled "Problems of Utilization of Aerospace Literature" and " Non -Literature Data in Aerospace and

  2. Environmentally regulated aerospace coatings

    NASA Technical Reports Server (NTRS)

    Morris, Virginia L.

    1995-01-01

    Aerospace coatings represent a complex technology which must meet stringent performance requirements in the protection of aerospace vehicles. Topcoats and primers are used, primarily, to protect the structural elements of the air vehicle from exposure to and subsequent degradation by environmental elements. There are also many coatings which perform special functions, i.e., chafing resistance, rain erosion resistance, radiation and electric effects, fuel tank coatings, maskants, wire and fastener coatings. The scheduled promulgation of federal environmental regulations for aerospace manufacture and rework materials and processes will regulate the emissions of photochemically reactive precursors to smog and air toxics. Aerospace organizations will be required to identify, qualify and implement less polluting materials. The elimination of ozone depleting chemicals (ODC's) and implementation of pollution prevention requirements are added constraints which must be addressed concurrently. The broad categories of operations affected are the manufacture, operation, maintenance, and repair of military, commercial, general aviation, and space vehicles. The federal aerospace regulations were developed around the precept that technology had to be available to support the reduction of organic and air toxic emissions, i.e., the regulations cannot be technology forcing. In many cases, the regulations which are currently in effect in the South Coast Air Quality Management District (SCAQMD), located in Southern California, were used as the baseline for the federal regulations. This paper addresses strategies used by Southern California aerospace organizations to cope with these regulatory impacts on aerospace productions programs. All of these regulatory changes are scheduled for implementation in 1993 and 1994, with varying compliance dates established.

  3. Aerospace Education. NSTA Position Statement

    ERIC Educational Resources Information Center

    National Science Teachers Association (NJ1), 2008

    2008-01-01

    National Science Teachers Association (NSTA) has developed a new position statement, "Aerospace Education." NSTA believes that aerospace education is an important component of comprehensive preK-12 science education programs. This statement highlights key considerations that should be addressed when implementing a high quality aerospace education…

  4. 78 FR 79687 - Texas Eastern Transmission, LP; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP14-29-000] Texas Eastern Transmission, LP; Notice of Application Take notice that on December 10, 2013 Texas Eastern Transmission, LP (Texas Eastern), at 5400 Westheimer Court, Houston, Texas 77056, filed an application in Docket No. CP14-29-000 pursuant to section 7(b) of...

  5. Interactions of Liquid Propellant/LP XM46 With Soils

    DTIC Science & Technology

    1994-09-01

    of the solution was plated for colony counting. Results Microbial populations before contact with I.P (controls) Bacteria were detected in BRL-SAS B...agars ( bacteria ) from the control and short-term contact tests .................... 96 Figure 3 i. Response of microfiora in Picatinny A soil to 1 hr...native actinomycetes, bacteria , and fungi after contact with LP or nmtrin, acid. Effects of washing the soil with water immediately after contact with LP

  6. Index of international publications in aerospace medicine.

    DOT National Transportation Integrated Search

    1993-02-01

    The Index of International Publications in Aerospace Medicine is a comprehensive listing of international publications in clinical aerospace medicine, operational aerospace medicine, aerospace physiology, environmental medicine/physiology, diving med...

  7. Index of international publications in aerospace medicine

    DOT National Transportation Integrated Search

    2001-08-01

    The Index of International Publications in Aerospace Medicine is a comprehensive listing of international publications in clinical aerospace medicine, operational aerospace medicine, aerospace physiology, environmental medicine/physiology, diving med...

  8. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 41: Technical communication practices of Dutch and US aerospace engineers and scientists: International perspective on aerospace

    NASA Technical Reports Server (NTRS)

    Barclay, Rebecca O.; Pinelli, Thomas E.; Kennedy, John M.

    1994-01-01

    As part of Phase 4 of the NASA/DOD Aerospace Knowledge Diffusion Research Project, studies were conducted that investigated the technical communications practices of Dutch and U.S. aerospace engineers and scientists. The studies had the following objectives: (1) to solicit the opinions of aerospace engineers and scientists regarding the importance of technical communication to their professions, (2) to determine the use and production of technical communication by aerospace engineers and scientists, (3) to investigate their use of libraries and technical information centers, (4) to investigate their use of and the importance to them of computer and information technology, (5) to examine their use of electronic networks, and (6) to determine their use of foreign and domestically produced technical reports. Self-administered (mail) questionnaires were distributed to Dutch aerospace engineers and scientists at the National Aerospace Laboratory (NLR) in the Netherlands, the NASA Ames Research Center in the U.S., and the NASA Langley Research Center in the U.S. Responses of the Dutch and U.S. participants to selected questions are presented in this paper.

  9. A New Algorithm for Detecting Cloud Height using OMPS/LP Measurements

    NASA Technical Reports Server (NTRS)

    Chen, Zhong; DeLand, Matthew; Bhartia, Pawan K.

    2016-01-01

    The Ozone Mapping and Profiler Suite Limb Profiler (OMPS/LP) ozone product requires the determination of cloud height for each event to establish the lower boundary of the profile for the retrieval algorithm. We have created a revised cloud detection algorithm for LP measurements that uses the spectral dependence of the vertical gradient in radiance between two wavelengths in the visible and near-IR spectral regions. This approach provides better discrimination between clouds and aerosols than results obtained using a single wavelength. Observed LP cloud height values show good agreement with coincident Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation (CALIPSO) measurements.

  10. Index of international publications in aerospace medicine.

    DOT National Transportation Integrated Search

    2014-05-01

    The 5th edition of the Index of International Publications in Aerospace Medicine is a comprehensive : listing of international publications in clinical aerospace medicine, operational aerospace medicine, : aerospace physiology, environmental medicine...

  11. Index of International Publications in Aerospace Medicine

    DOT National Transportation Integrated Search

    2007-01-01

    The 3rd edition of theIndex of International Publications in Aerospace Medicine is a comprehensive listing of : international publications in clinical aerospace medicine, operational aerospace medicine, aerospace : physiology, environmental medicine/...

  12. Kelvin waves in the tropical stratosphere observed in OMPS-LP ozone measurements

    NASA Astrophysics Data System (ADS)

    Randel, W. J.; Park, M.

    2017-12-01

    We investigate equatorial waves in the tropical stratosphere using OMPS limb profiler (LP) ozone measurements spanning 2012-2017. The OMPS-LP data show clear evidence of eastward propagating planetary-scale Kelvin waves with periods near 15-20 days, and these feature are strongly modulated by the background winds linked to the quasi-biennial oscillation (QBO). We study coherence between OMPS-LP ozone and GPS radio occultation temperature measurements, and use these analyses to evaluate data quality and variability in the tropical stratosphere.

  13. 75 FR 27334 - Regency Intrastate Gas LP; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-14

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-20-000] Regency Intrastate Gas LP; Notice of Baseline Filing May 7, 2010. Take notice that on April 30, 2010, Regency Intrastate Gas LP (Regency) submitted its baseline filing of its Statement of Operating Conditions for...

  14. Aerospace Dermatology

    PubMed Central

    Arora, Sandeep

    2017-01-01

    Evolutionarily, man is a terrestrial mammal, adapted to land. Aviation and now space/microgravity environment, hence, pose new challenges to our physiology. Exposure to these changes affects the human body in acute and chronic settings. Since skin reflects our mental and physical well-being, any change/side effects of this environment shall be detected on the skin. Aerospace industry offers a unique environment with a blend of all possible occupational disorders, encompassing all systems of the body, particularly the skin. Aerospace dermatologists in the near future shall be called upon for their expertise as we continue to push human physiological boundaries with faster and more powerful military aircraft and look to colonize space stations and other planets. Microgravity living shall push dermatology into its next big leap-space, the final frontier. This article discusses the physiological effects of this environment on skin, effect of common dermatoses in aerospace environment, effect of microgravity on skin, and occupational hazards of this industry. PMID:28216729

  15. Aerospace Dermatology.

    PubMed

    Arora, Sandeep

    2017-01-01

    Evolutionarily, man is a terrestrial mammal, adapted to land. Aviation and now space/microgravity environment, hence, pose new challenges to our physiology. Exposure to these changes affects the human body in acute and chronic settings. Since skin reflects our mental and physical well-being, any change/side effects of this environment shall be detected on the skin. Aerospace industry offers a unique environment with a blend of all possible occupational disorders, encompassing all systems of the body, particularly the skin. Aerospace dermatologists in the near future shall be called upon for their expertise as we continue to push human physiological boundaries with faster and more powerful military aircraft and look to colonize space stations and other planets. Microgravity living shall push dermatology into its next big leap-space, the final frontier. This article discusses the physiological effects of this environment on skin, effect of common dermatoses in aerospace environment, effect of microgravity on skin, and occupational hazards of this industry.

  16. Amplitude and Recurrence Time of LP activity at Mt. Etna, Italy

    NASA Astrophysics Data System (ADS)

    Cauchie, Léna; Saccorotti, Gilberto; Bean, Christopher

    2013-04-01

    The manifestation of Long-Period (LP) activity is attested on many volcanoes worldwide and is thought to be associated with the resonant oscillations of subsurface, fluid-filled, cracks and conduits. Nonetheless the actual source mechanism that originates the resonance is still unclear. Different models have been proposed so far, including (i) fluid flow instabilities as periodic degassing and (ii) brittle failure in viscous magmas. Since LP activity usually precedes and accompanies volcanic eruption, the understanding of these sources is crucial for the hazard assessment and eruption early warning. The work is aimed at improving the understanding of the LP source mechanism through a statistical analysis of detailed LP catalogues. The behaviour of LP activity is compared with the empirical laws governing earthquakes recurrence (e.g., Gutenberg-Richter [GR] and Gamma-law distributions), in order to understand what relationships, if any, exist between these two apparently different earthquake classes. In particular, about 13000 events were detected on Mount Etna in August 2005 through a STA/LTA method. For this given period, the volcano does not present particular sign of unrest. The manifestation of the LP events is sustained in time over all the period of analysis. From the analysis of the directional properties, it turns out that the events of this first catalog propagate from 2 distinct sources . Furthermore, the events exhibit a high degree of waveform similarity, and provide a criterion for classification/source separation. The events were then grouped into families of comparable waveforms, resulting also in a separation for their source locations. We then used template signals of each family for a Matched-Filtering of the continuous data streams, in order to discriminate small-amplitude events previously undetected by the STA/LTA triggering method. This procedure allowed for a significant enrichment of the catalogues. The retrieved amplitude distributions

  17. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 39: The role of computer networks in aerospace engineering

    NASA Technical Reports Server (NTRS)

    Bishop, Ann P.; Pinelli, Thomas E.

    1994-01-01

    This paper presents selected results from an empirical investigation into the use of computer networks in aerospace engineering. Such networks allow aerospace engineers to communicate with people and access remote resources through electronic mail, file transfer, and remote log-in. The study drew its subjects from private sector, government and academic organizations in the U.S. aerospace industry. Data presented here were gathered in a mail survey, conducted in Spring 1993, that was distributed to aerospace engineers performing a wide variety of jobs. Results from the mail survey provide a snapshot of the current use of computer networks in the aerospace industry, suggest factors associated with the use of networks, and identify perceived impacts of networks on aerospace engineering work and communication.

  18. Measurement of Lp(a) with a two-step monoclonal competitive sandwich ELISA method.

    PubMed

    Morikawa, W; Iki, R; Terano, T; Funatsu, A; Sugiuchi, H; Uji, Y; Okabe, H

    1995-06-01

    To evaluate the results of Lipoprotein (a)[Lp(a)] measurements by a competitive two-step monoclonal enzyme-linked immuno sorbent assay method comparing them with those by a conventional ELISA. Serum having various isoforms of Lp(a) and purified Lp(a) were assayed using the method described here and commercially available kits. The reference range was determined with the use of 324 normal subjects by means of calculation from Lp(a) results of logarithmic transformation. Our method takes advantage of a competitive reaction between fixed antibody and free antibody to Lp(a), having the detection range up to 1000 mg/L with the lowest detection limit of 2 mg/L. The anti-Lp(a) monoclonal antibody employed in the assay system reacts uniformly with all phenotypes of Lp(a) but showing very low cross-reactivity for plasminogen and LDL. Within-run and between-run precisions were excellent, giving CVs of 2.9 and 4.0% with mean values of 145 and 635 mg/L, respectively. In comparison of the results by our method with those by a polyclonal method (Biopool) or a monoclonal antibody method (Terumo), they correlated well; Y (our method) = 0.99 x (polyclonal method, Biopool) - 1.9, r = 0.994 (n = 60), and Y = 0.94 X(monoclonal method, Terumo) -9.8, r = 0.97 (n = 60), respectively. The reference range was 105.9 +/- 25.4 mg/L, the difference between the sexes was not significant. Our method has proven highly accurate and specific. It is applicable with auto analyzer because it does not require such a pre-dilution step as is necessary for Lp(a) determination by conventional ELISA assay. Accordingly, we can conclude that our test method is workable for both clinical laboratories and mass screening.

  19. Aerospace engineering educational program

    NASA Technical Reports Server (NTRS)

    Craft, William; Klett, David; Lai, Steven

    1992-01-01

    The principle goal of the educational component of NASA CORE is the creation of aerospace engineering options in the mechanical engineering program at both the undergraduate and graduate levels. To accomplish this goal, a concerted effort during the past year has resulted in detailed plans for the initiation of aerospace options in both the BSME and MSME programs in the fall of 1993. All proposed new courses and the BSME aerospace option curriculum must undergo a lengthy approval process involving two cirriculum oversight committees (School of Engineering and University level) and three levels of general faculty approval. Assuming approval is obtained from all levels, the options will officially take effect in Fall '93. In anticipation of this, certain courses in the proposed curriculum are being offered during the current academic year under special topics headings so that current junior level students may graduate in May '94 under the BSME aerospace option. The proposed undergraduate aerospace option curriculum (along with the regular mechanical engineering curriculum for reference) is attached at the end of this report, and course outlines for the new courses are included in the appendix.

  20. 76 FR 81925 - Freeport LNG Development, L.P.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

    ... Development, L.P.; Notice of Application Take notice that on December 9, 2011, Freeport LNG Development, L.P... questions regarding this application should be directed to Lisa M. Tonery, Fulbright & Jaworski L.L.P., 666...-Filing'' link. The Commission strongly encourages electronic filings. Comment Date: 5 p.m. Eastern Time...

  1. Amplitude and recurrence time analysis of LP activity at Mount Etna, Italy

    NASA Astrophysics Data System (ADS)

    Cauchie, Léna; Saccorotti, Gilberto; Bean, Christopher J.

    2015-09-01

    The aim of this work is to improve our understanding of the long-period (LP) source mechanism at Mount Etna (Italy) through a statistical analysis of detailed LP catalogues. The behavior of LP activity is compared with the empirical laws governing earthquake recurrence, in order to investigate whether any relationships exist between these two apparently different earthquake classes. We analyzed a family of 8894 events detected during a temporary experiment in August 2005. For that time interval, the LP activity is sustained in time and the volcano did not exhibit any evident sign of unrest. The completeness threshold of the catalogue is established through a detection test based on synthetic waveforms. The retrieved amplitude distribution differs significantly from the Gutenberg-Richter law, and the interevent times distribution does not follow the typical γ law, expected for tectonic activity. In order to compare these results with a catalogue for which the source mechanism is well established, we applied the same procedure to a data set from Stromboli Volcano, where recurrent LP activity is closely related to very-long-period pulses, in turn associated with the summit explosions. Our results indicate that the two catalogues exhibit similar behavior in terms of amplitude and interevent time distributions. This suggests that the Etna's LP signals are most likely driven by stress changes caused by an intermittent degassing process occurring at depth, similar to that which drives the summit explosions at Stromboli Volcano.

  2. Women in Aerospace Awards

    NASA Image and Video Library

    2010-10-26

    NASA Administrator Charlie Bolden holds up a photograph showing four female Astronauts onboard the Space Station during his presentation at the Women in Aerospace (WIA) organization's annual awards ceremony and banquet at the Ritz-Carlton Hotel in Arlington, VA on Tuesday, Oct. 26, 2010. Bolden presented Women in Aerospace's Outstanding Member Award to NASA Deputy Administrator Lori Garver, noting her ongoing leadership and participation in Women in Aerospace and her passion and dedication to opening the high frontier of space to the everyday person. Photo Credit: (NASA/Bill Ingalls)

  3. The role of indoleamine 2,3-dioxygenase in LP-BPM5 murine retroviral disease progression.

    PubMed

    O'Connor, Megan A; Green, William R

    2013-05-17

    Indoleamine 2,3-dioxygenase (IDO) is an immunomodulatory intracellular enzyme involved in tryptophan degradation. IDO is induced during cancer and microbial infections by cytokines, ligation of co-stimulatory molecules and/or activation of pattern recognition receptors, ultimately leading to modulation of the immune response. LP-BM5 murine retroviral infection induces murine AIDS (MAIDS), which is characterized by profound and broad immunosuppression of T- and B-cell responses. Our lab has previously described multiple mechanisms regulating the development of immunodeficiency of LP-BM5-induced disease, including Programmed Death 1 (PD-1), IL-10, and T-regulatory (Treg) cells. Immunosuppressive roles of IDO have been demonstrated in other retroviral models, suggesting a possible role for IDO during LP-BM5-induced retroviral disease progression and/or development of viral load. Mice deficient in IDO (B6.IDO-/-) and wildtype C57BL/6 (B6) mice were infected with LP-BM5 murine retrovirus. MAIDS and LP-BM5 viral load were assessed at termination. As expected, IDO was un-inducible in B6.IDO-/- during LP-BM5 infection. B6.IDO-/- mice infected with LP-BM5 retrovirus succumbed to MAIDS as indicated by splenomegaly, serum hyper IgG2a and IgM, decreased responsiveness to B- and T-cell mitogens, conversion of a proportion of CD4+ T cells from Thy1.2+ to Thy1.2-, and increased percentages of CD11b+Gr-1+ cells. LP-BM5 infected B6.IDO-/- mice also demonstrated the development of roughly equivalent disease kinetics as compared to infected B6 mice. Splenic viral loads of B6 and B6.IDO-/- mice were also equivalent after infection as measured by LP-BM5-specific Def Gag and Eco Gag viral mRNA, determined by qRT-PCR. Collectively, these results demonstrate IDO neither plays an essential role, nor is required, in LP-BM5-induced disease progression or LP-BM5 viral load.

  4. The role of indoleamine 2,3-dioxygenase in LP-BPM5 murine retroviral disease progression

    PubMed Central

    2013-01-01

    Background Indoleamine 2,3-dioxygenase (IDO) is an immunomodulatory intracellular enzyme involved in tryptophan degradation. IDO is induced during cancer and microbial infections by cytokines, ligation of co-stimulatory molecules and/or activation of pattern recognition receptors, ultimately leading to modulation of the immune response. LP-BM5 murine retroviral infection induces murine AIDS (MAIDS), which is characterized by profound and broad immunosuppression of T- and B-cell responses. Our lab has previously described multiple mechanisms regulating the development of immunodeficiency of LP-BM5-induced disease, including Programmed Death 1 (PD-1), IL-10, and T-regulatory (Treg) cells. Immunosuppressive roles of IDO have been demonstrated in other retroviral models, suggesting a possible role for IDO during LP-BM5-induced retroviral disease progression and/or development of viral load. Methods Mice deficient in IDO (B6.IDO−/−) and wildtype C57BL/6 (B6) mice were infected with LP-BM5 murine retrovirus. MAIDS and LP-BM5 viral load were assessed at termination. Results As expected, IDO was un-inducible in B6.IDO−/− during LP-BM5 infection. B6.IDO−/− mice infected with LP-BM5 retrovirus succumbed to MAIDS as indicated by splenomegaly, serum hyper IgG2a and IgM, decreased responsiveness to B- and T-cell mitogens, conversion of a proportion of CD4+ T cells from Thy1.2+ to Thy1.2-, and increased percentages of CD11b+Gr-1+ cells. LP-BM5 infected B6.IDO−/− mice also demonstrated the development of roughly equivalent disease kinetics as compared to infected B6 mice. Splenic viral loads of B6 and B6.IDO−/− mice were also equivalent after infection as measured by LP-BM5-specific Def Gag and Eco Gag viral mRNA, determined by qRT-PCR. Conclusions Collectively, these results demonstrate IDO neither plays an essential role, nor is required, in LP-BM5-induced disease progression or LP-BM5 viral load. PMID:23680027

  5. Anatomy of the hyper-runaway star LP 40-365 with Gaia

    NASA Astrophysics Data System (ADS)

    Raddi, R.; Hollands, M. A.; Gänsicke, B. T.; Townsley, D. M.; Hermes, J. J.; Gentile Fusillo, N. P.; Koester, D.

    2018-06-01

    LP 40-365 (aka GD 492) is a nearby low-luminosity hyper-runaway star with an extremely unusual atmospheric composition, which has been proposed as the remnant of a white dwarf that survived a subluminous Type Ia supernova (SN Ia) in a single-degenerate scenario. Adopting the Gaia Data Release (DR2) parallax, ϖ = 1.58 ± 0.03 mas, we estimate a radius of 0.18 ± 0.01 R⊙, confirming LP 40-365 as a subluminous star that is ≃ 15 times larger than a typical white dwarf and is compatible with the SN Ia remnant scenario. We present an updated kinematic analysis, making use of the Gaia parallax and proper motion, and confirm that LP 40-365 is leaving the Milky Way at about 1.5 times the escape velocity of the Solar neighbourhood with a rest-frame velocity of 852 ± 10 km s-1. Integrating the past trajectories of LP 40-365, we confirm it crossed the Galactic disc 5.0 ± 0.3 Myr ago in the direction of Carina, likely coming from beneath the plane. Finally, we estimate that LP 40-365 was ejected from its progenitor binary with a velocity of at least 600 km s-1, which is compatible with theoretical predictions for close binaries containing a white dwarf and a helium-star donor.

  6. Lightning Protection Guidelines for Aerospace Vehicles

    NASA Technical Reports Server (NTRS)

    Goodloe, C. C.

    1999-01-01

    This technical memorandum provides lightning protection engineering guidelines and technical procedures used by the George C. Marshall Space Flight Center (MSFC) Electromagnetics and Aerospace Environments Branch for aerospace vehicles. The overviews illustrate the technical support available to project managers, chief engineers, and design engineers to ensure that aerospace vehicles managed by MSFC are adequately protected from direct and indirect effects of lightning. Generic descriptions of the lightning environment and vehicle protection technical processes are presented. More specific aerospace vehicle requirements for lightning protection design, performance, and interface characteristics are available upon request to the MSFC Electromagnetics and Aerospace Environments Branch, mail code EL23.

  7. 78 FR 53487 - Equinox Funds Trust and Equinox Institutional Asset Management LP; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-29

    ... Funds Trust and Equinox Institutional Asset Management LP; Notice of Application August 23, 2013. AGENCY...: Equinox Funds Trust (the ``Trust'') and Equinox Institutional Asset Management LP (the ``Initial Adviser... Institutional Asset Management LP, 47 Hulfish Street, Suite 510, Princeton, NJ 08542; Daniel Prezioso, Equinox...

  8. Association of freezing tolerance to LpCBFIIIb and LpCBFIIIc gene polymorphism in perennial ryegrass accessions

    USDA-ARS?s Scientific Manuscript database

    CBF/DREB related genes are considered important genes for regulation of abiotic stress in plants. In this study, CBF/DREB genes in perennial ryegrass (Lolium perenne L.), also known as LpCBF genes, were resequenced from several cultivated and landrace plants from a worldwide collection. The same pla...

  9. Is Lp(a) ready for prime time use in the clinic? A pros-and-cons debate.

    PubMed

    Kostner, Karam M; Kostner, Gert M; Wierzbicki, Anthony S

    2018-04-30

    Lipoprotein (a) (Lp(a)) is a cholesterol-rich lipoprotein known since 1963. In spite of extensive research on Lp(a), there are still numerous gaps in our knowledge relating to its function, biosynthesis and catabolism. One reason for this might be that apo(a), the characteristic glycoprotein of Lp(a), is expressed only in primates. Results from experiments using transgenic animals therefore may need verification in humans. Studies on Lp(a) are also handicapped by the great number of isoforms of apo(a) and the heterogeneity of apo(a)-containing fractions in plasma. Quantification of Lp(a) in the clinical laboratory for a long time has not been standardized. Starting from its discovery, reports accumulated that Lp(a) contributed to the risk of cardiovascular disease (CVD), myocardial infarction (MI) and stroke. Early reports were based on case control studies but in the last decades a great deal of prospective studies have been published that highlight the increased risk for CVD and MI in patients with elevated Lp(a). Final answers to the question of whether Lp(a) is ready for wider clinical use will come from intervention studies with novel selective Lp(a) lowering medications that are currently underway. This article expounds arguments for and against this proposition from currently available data. Copyright © 2018 Elsevier B.V. All rights reserved.

  10. Diagnostic value of CRP and Lp(a) in coronary heart disease.

    PubMed

    Erbağci, Ayşe Binnur; Tarakçioğlu, Mehmet; Aksoy, Mehmet; Kocabaş, Ramazan; Nacak, Muradiye; Aynacioğlu, A Sükrü; Sivrikoz, Cumhur

    2002-06-01

    Increased lipoprotein (a) [Lp(a)] concentration was reported to be an independent risk factor for coronary heart disease (CHD). Recent epidemiological studies affirmed the value of C-reactive protein (CRP) as the strongest, univariate predictor of the cardiovascular events. We decided to establish cut-off levels providing maximum diagnostic efficiency for CHD. In this study we measured CRP and Lp(a) concentrations in patients with angiographically demonstrated CHD (group A, n: 120), patients without any angiographically demonstrable lesion (group B, n: 62) and a group of healthy subjects (group C, n: 41). Data were evaluated correcting for lipid and lipoprotein concentrations, diabetes mellitus, hypertension, smoking, age, and body mass index in men and women. ROC curve based cut-off values (comparing group A versus groups B and C) and associated diagnostic performances of the assays were evaluated. Significant increases were noted in serum CRP concentrations in men and women, in groups A vs. B,A vs. C, B vs. C. Lp(a) concentrations were not different among groups in men but were higher in group A vs. B and C in women. Optimal cut-off levels for CRP in women and men were found as 2.1 and 3.0 mg/l with the diagnostic values of 0.792 and 0.770, respectively. For Lp(a) optimal cut-off levels were found as 22.6 and 9.8 mg/dl with the diagnostic values of 0.612 and 0.596 in women and men, respectively. The CRP level is quite efficient for separation of patients from controls. Therefore keeping in mind the lack of specificity, the CRP level may be a useful tool in the diagnosis of coronary heart disease. However, the Lp(a) level is not efficient enough to support the use of Lp(a) measurement for management of coronary heart disease.

  11. 77 FR 70432 - Magic Valley Pipeline, L.P.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... Pipeline, L.P.; Notice of Filing Take notice that on November 15, 2012, Magic Valley Pipeline, L.P. (Magic...: 5:00 p.m. Eastern Time on Tuesday, November 27, 2012. Dated: November 19, 2012. Kimberly D. Bose, Secretary. [FR Doc. 2012-28544 Filed 11-23-12; 8:45 am] BILLING CODE 6717-01-P ...

  12. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 12: The diffusion of federally funded aerospace research and development (R/D) and the information seeking behavior of US aerospace engineers and scientists

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Kennedy, John M.; Barclay, Rebecca O.

    1991-01-01

    In this paper, the diffusion of federally funded aerospace R&D is explored from the perspective of the information-seeking behavior of U.S. aerospace engineers and scientists. The following three assumptions frame this exploration: (1) knowledge production, transfer, and utilization are equally important components of the aerospace R&D process; (2) the diffusion of knowledge resulting from federally funded aerospace R&D is indispensable for the U.S. to remain a world leader in aerospace; and (3) U.S. government technical reports, produced by NASA and DOD, play an important, but as yet undefined, role in the diffusion of federally funded aerospace R&D. A conceptual model for federally funded aerospace knowledge diffusion, one that emphasizes U.S. goverment technical reports, is presented. Data regarding three research questions concerning the information-seeking behavior of U.S. aerospace engineers and scientists are also presented.

  13. Neural Network Based Modeling and Analysis of LP Control Surface Allocation

    NASA Technical Reports Server (NTRS)

    Langari, Reza; Krishnakumar, Kalmanje; Gundy-Burlet, Karen

    2003-01-01

    This paper presents an approach to interpretive modeling of LP based control allocation in intelligent flight control. The emphasis is placed on a nonlinear interpretation of the LP allocation process as a static map to support analytical study of the resulting closed loop system, albeit in approximate form. The approach makes use of a bi-layer neural network to capture the essential functioning of the LP allocation process. It is further shown via Lyapunov based analysis that under certain relatively mild conditions the resulting closed loop system is stable. Some preliminary conclusions from a study at Ames are stated and directions for further research are given at the conclusion of the paper.

  14. Automated Test Assembly Using lp_Solve Version 5.5 in R

    ERIC Educational Resources Information Center

    Diao, Qi; van der Linden, Wim J.

    2011-01-01

    This article reviews the use of the software program lp_solve version 5.5 for solving mixed-integer automated test assembly (ATA) problems. The program is freely available under Lesser General Public License 2 (LGPL2). It can be called from the statistical language R using the lpSolveAPI interface. Three empirical problems are presented to…

  15. Anechoic Chambers: Aerospace Applications. (Latest Citations from the Aerospace Database)

    NASA Technical Reports Server (NTRS)

    1996-01-01

    The bibliography contains citations concerning the design, development, performance, and applications of anechoic chambers in the aerospace industry. Anechoic chamber testing equipment, techniques for evaluation of aerodynamic noise, microwave and radio antennas, and other acoustic measurement devices are considered. Shock wave studies on aircraft models and components, electromagnetic measurements, jet flow studies, and antenna radiation pattern measurements for industrial and military aerospace equipment are discussed. (Contains 50-250 citations and includes a subject term index and title list.)

  16. Anechoic Chambers: Aerospace Applications. (Latest Citations from the Aerospace Database)

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The bibliography contains citations concerning the design, development, performance, and applications of anechoic chambers in the aerospace industry. Anechoic chamber testing equipment, techniques for evaluation of aerodynamic noise, microwave and radio antennas, and other acoustic measurement devices are considered. Shock wave studies on aircraft models and components, electromagnetic measurements, jet flow studies, and antenna radiation pattern measurements for industrial and military aerospace equipment are discussed. (Contains 50-250 citations and includes a subject term index and title list.)

  17. 75 FR 22125 - Trans-Union Interstate Pipeline, L.P.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-27

    ... Interstate Pipeline, L.P.; Notice of Filing April 20, 2010. Take notice that on April 9, 2010 Trans-Union Interstate Pipeline, L.P. submitted a request for waiver of the requirement to submit the 2009 FERC Form No... am] BILLING CODE 6717-01-P ...

  18. Welcome to the Ohio Aerospace Institute

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The mission and various programs administered by the Ohio Aerospace Institute, a consortium made up of 9 Ohio Universities, LeRC, and members of the Aerospace Industry are described. The video highlights the following: programs to bring aerospace research to K-12 classrooms; programs to allow graduate students access to laboratory equipment at LeRC; the creation of a statewide television network to link researchers in industry and academia; and focus groups to encourage collaboration between companies in aerospace research.

  19. Effect of Lactobacillus plantarum LP-Onlly on gut flora and colitis in interleukin-10 knockout mice.

    PubMed

    Xia, Yang; Chen, Hong-Qi; Zhang, Min; Jiang, Yan-Qun; Hang, Xiao-Min; Qin, Huan-Long

    2011-02-01

    Probiotics are used in the therapy of inflammatory bowel disease. This study aimed to determine the effects of probiotic Lactobacillus plantarum LP-Onlly (LP) on gut flora and colitis in interleukin-10 knockout (IL-10(-/-) ) mice, a model of spontaneous colitis. IL-10(-/-) and wild-type mice were used at 8 weeks of age and LP by gavage was administered at a dose of 10(9) cells/day per mice for 4 weeks. Mice were maintained for another one week without LP treatment. The colonic tissues were collected for histological and ultrastructural analysis at death after 4 weeks treatment of LP, and the feces were collected at 1-week intervals throughout the experiment for the analysis of gut flora and LP using selective culture-based techniques. Compared with control mice, IL-10(-/-) mice developed a severe intestinal inflammation and tissue damage, and had an abnormal composition of gut microflora. LP administration attenuated colitis with the decreased inflammatory scoring and histological injury in the colon of IL-10(-/-) mice. In addition, LP administration increased the numbers of beneficial total bifidobacteria and lactobacilli, and decreased the numbers of potential pathogenic enterococci and Clostridium perfringens, although the decrease of coliforms was not significant after LP treatment in IL-10(-/-) mice. Oral administration of LP was effective in the treatment of colitis, with the direct modification of gut microflora in IL-10(-/-) mice. This probiotic strain could be used as a potential adjuvant in the therapy of inflammatory bowel disease, although further studies are required in human. © 2011 Journal of Gastroenterology and Hepatology Foundation and Blackwell Publishing Asia Pty Ltd.

  20. 77 FR 74280 - Proposed Information Collection (Learner's Perception (LP) Survey); Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-13

    ... (Learner's Perception (LP) Survey); Comment Request AGENCY: Veterans Health Administration, Department of... techniques or the use of other forms of information technology. Title: Learner's Perception (LP) Survey, VA... collection. Abstract: VA Form 10-0439 will be use to obtain health care trainees perception of their clinical...

  1. 77 FR 50487 - Application To Export Electric Energy; RBC Energy Services LP

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ... DEPARTMENT OF ENERGY [OE Docket No. EA-328-A] Application To Export Electric Energy; RBC Energy Services LP AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: RBC Energy Services LP (RBC Energy) has applied to renew its authority to transmit...

  2. Lp-estimates on diffusion processes

    NASA Astrophysics Data System (ADS)

    Yan, Litan; Zhu, Bei

    2005-03-01

    Let be a diffusion process on given by where B=(Bt)t[greater-or-equal, slanted]0 is a standard Brownian motion starting at zero and [mu],[sigma] are two continuous functions on , and [sigma](x)>0 if x[not equal to]0. For a nonnegative continuous function [phi] we define the functional by , t[greater-or-equal, slanted]0. Then under suitable conditions we establish the relationship between Lp-norm of sup0[less-than-or-equals, slant]t[less-than-or-equals, slant][tau]Xt and Lp-norm of J[tau] for all stopping times [tau]. In particular, for a Bessel process Z of dimension [delta]>0 starting at zero, we show that the inequalities hold for all 00, where Cp and cp are some positive constants depending only on p, and H[mu],h[mu] are the inverses of x|->(e2[mu]x-2[mu]x-1)/2[mu]2 and x|->(e-2[mu]x+2[mu]x-1)/2[mu]2 on (0,[infinity]), respectively.

  3. 77 FR 29624 - Cheniere Creole Trail Pipeline, L.P.; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-18

    ... Creole Trail Pipeline, L.P.; Notice of Application Take notice that on April 30, 2012, Cheniere Creole Trail Pipeline, L.P. (Cheniere), 700 Milam, Suite 800, Houston, TX 77002, filed an application in Docket... Creole Trail Expansion Project (Project). Cheniere's Project would consist of construction of a new 53...

  4. 76 FR 20971 - Eagle Rock Desoto Pipeline, L.P.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-14

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-120-001] Eagle Rock Desoto Pipeline, L.P.; Notice of Filing Take notice that on April 7, 2011, Eagle Rock Desoto Pipeline, L.P. filed a revised Statement of Operating Conditions to comply with an unpublished delegated letter...

  5. Aerospace management techniques: Commercial and governmental applications

    NASA Technical Reports Server (NTRS)

    Milliken, J. G.; Morrison, E. J.

    1971-01-01

    A guidebook for managers and administrators is presented as a source of useful information on new management methods in business, industry, and government. The major topics discussed include: actual and potential applications of aerospace management techniques to commercial and governmental organizations; aerospace management techniques and their use within the aerospace sector; and the aerospace sector's application of innovative management techniques.

  6. 78 FR 21929 - TexStar Crude Oil Pipeline, LP; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. AC13-63-000] TexStar Crude Oil Pipeline, LP; Notice of Filing Take notice that on March 26, 2013, TexStar Crude Oil Pipeline, LP (TexStar) submitted to the Federal Energy Regulatory Commission (Commission) a request for waiver of...

  7. 75 FR 63452 - Lobo Pipeline Company L.P.; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... Company L.P.; Notice of Baseline Filing October 7, 2010. Take notice that on October 1, 2010, Lobo Pipeline Company L.P. submitted a revised baseline filing of its Statement of Operating Conditions for... free). For TTY, call (202) 502-8659. Comment Date: 5 p.m. Eastern time on Wednesday, October 20, 2010...

  8. Structure and Antitumor and Immunomodulatory Activities of a Water-Soluble Polysaccharide from Dimocarpus longan Pulp

    PubMed Central

    Meng, Fa-Yan; Ning, Yuan-Ling; Qi, Jia; He, Zhou; Jie, Jiang; Lin, Juan-Juan; Huang, Yan-Jun; Li, Fu-Sen; Li, Xue-Hua

    2014-01-01

    A new water-soluble polysaccharide (longan polysaccharide 1 (LP1)) was extracted and successfully purified from Dimocarpus longan pulp via diethylaminoethyl (DEAE)-cellulose anion-exchange and Sephacryl S-300 HR gel chromatography. The chemical structure was determined using Infrared (IR), gas chromatography (GC) and nuclear magnetic resonance (NMR) analysis. The results indicated that the molecular weight of the sample was 1.1 × 105 Da. Monosaccharide composition analysis revealed that LP1 was composed of Glc, GalA, Ara and Gal in a molar ratio of 5.39:1.04:0.74:0.21. Structural analysis indicated that LP1 consisted of a backbone of →4)-α-d-Glcp-(1→4)-α-d-GalpA-(1→4)-α-d-Glcp-(1→4)-β-d-Glcp-(1→ units with poly saccharide side chains composed of →2)-β-d-Fruf-(1→2)-l-sorbose-(1→ attached to the O-6 position of the α-d-Glcp residues. In vitro experiments indicated that LP1 had significantly high antitumor activity against SKOV3 and HO8910 tumor cells, with inhibition percentages of 40% and 50%, respectively. In addition, LP1 significantly stimulated the production of the cytokine interferon-γ (IFN-γ), increased the activity of murine macrophages and enhanced B- and T-lymphocyte proliferation. The results of this study demonstrate that LP1 has potential applications as a natural antitumor agent with immunomodulatory activity. PMID:24663085

  9. LP 543-25: A Rare Low-mass Runaway Disk Star

    NASA Astrophysics Data System (ADS)

    de la Fuente Marcos, Raúl; de la Fuente Marcos, Carlos

    2018-05-01

    LP 543-25 or PSS 544-7 is a high proper-motion star located 458 pc from the Sun in the constellation of Canis Minor; it has been argued that it could be a candidate cannonball star ejected by a star cluster. Here, we revisit the issue of the kinematics of this interesting star using Gaia DR2. The heliocentric Galactic velocity components are (U, V, W) = (206, -289, 30) km/s; the corresponding Galactocentric Galactic velocity components show that LP 543-25 is moving in the Galactic plane and away from the Galactic Center at a rate of nearly 200 km/s, which is compatible with an origin in one of the multiple star clusters that inhabit the inner regions of the Milky Way. LP 543-25 appears to be a member of an elusive class of stars, the low-mass runaway stars. It is perhaps one of the closest and less massive runaway stars identified so far.

  10. 65 nm LP/GP mix low cost platform for multi-media wireless and consumer applications

    NASA Astrophysics Data System (ADS)

    Tavel, B.; Duriez, B.; Gwoziecki, R.; Basso, M. T.; Julien, C.; Ortolland, C.; Laplanche, Y.; Fox, R.; Sabouret, E.; Detcheverry, C.; Boeuf, F.; Morin, P.; Barge, D.; Bidaud, M.; Biénacel, J.; Garnier, P.; Cooper, K.; Chapon, J. D.; Trouiller, Y.; Belledent, J.; Broekaart, M.; Gouraud, P.; Denais, M.; Huard, V.; Rochereau, K.; Difrenza, R.; Planes, N.; Marin, M.; Boret, S.; Gloria, D.; Vanbergue, S.; Abramowitz, P.; Vishnubhotla, L.; Reber, D.; Stolk, P.; Woo, M.; Arnaud, F.

    2006-04-01

    A complete 65 nm CMOS platform, called LP/GP Mix, has been developed employing thick oxide transistor (IO), Low Power (LP) and General Purpose (GP) devices on the same chip. Dedicated to wireless multi-media and consumer applications, this new triple gate oxide platform is low cost (+1mask only) and saves over 35% of dynamic power with the use of the low operating voltage GP. The LP/GP mix shows competitive digital performance with a ring oscillator (FO = 1) speed equal to 7 ps per stage (GP) and 6T-SRAM static power lower than 10 pA/cell (LP). Compatible with mixed-signal design requirements, transistors show high voltage gain, low mismatch factor and low flicker noise. Moreover, to address mobile phone demands, excellent RF performance has been achieved with FT = 160 GHz for LP and 280 GHz for GP nMOS transistors.

  11. Heat transfer in aerospace propulsion

    NASA Technical Reports Server (NTRS)

    Simoneau, Robert J.; Hendricks, Robert C.; Gladden, Herbert J.

    1988-01-01

    Presented is an overview of heat transfer related research in support of aerospace propulsion, particularly as seen from the perspective of the NASA Lewis Research Center. Aerospace propulsion is defined to cover the full spectrum from conventional aircraft power plants through the Aerospace Plane to space propulsion. The conventional subsonic/supersonic aircraft arena, whether commercial or military, relies on the turbine engine. A key characteristic of turbine engines is that they involve fundamentally unsteady flows which must be properly treated. Space propulsion is characterized by very demanding performance requirements which frequently push systems to their limits and demand tailored designs. The hypersonic flight propulsion systems are subject to severe heat loads and the engine and airframe are truly one entity. The impact of the special demands of each of these aerospace propulsion systems on heat transfer is explored.

  12. [NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 7:] The NASA/DOD Aerospace Knowledge Diffusion Research Project: The DOD perspective

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Kennedy, John M.

    1990-01-01

    This project will provide descriptive and analytical data regarding the flow of STI at the individual, organizational, national, and international levels. It will examine both the channels used to communicate information and the social system of the aerospace knowledge diffusion process. Results of the project should provide useful information to R and D managers, information managers, and others concerned with improving access to and use of STI. Objectives include: (1) understanding the aerospace knowledge diffusion process at the individual, organizational, and national levels, placing particular emphasis on the diffusion of Federally funded aerospace STI; (2) understanding the international aerospace knowledge diffusion process at the individual and organizational levels, placing particular emphasis on the systems used to diffuse the results of Federally funded aerospace STI; (3) understanding the roles NASA/DoD technical report and aerospace librarians play in the transfer and use of knowledge derived from Federally funded aerospace R and D; (4) achieving recognition and acceptance within NASA, DoD and throughout the aerospace community that STI is a valuable strategic resource for innovation, problem solving, and productivity; and (5) providing results that can be used to optimize the effectiveness and efficiency of the Federal STI aerospace transfer system and exchange mechanism.

  13. Unification - An international aerospace information issue

    NASA Technical Reports Server (NTRS)

    Cotter, Gladys A.; Lahr, Thomas F.

    1992-01-01

    Scientific and Technical Information (STI) represents the results of large investments in research and development (R&D) and the expertise of a nation and is a valuable resource. For more than four decades, NASA and its predecessor organizations have developed and managed the preeminent aerospace information system. NASA obtains foreign materials through its international exchange relationships, continually increasing the comprehensiveness of the NASA Aerospace Database (NAD). The NAD is de facto the international aerospace database. This paper reviews current NASA goals and activities with a view toward maintaining compatibility among international aerospace information systems, eliminating duplication of effort, and sharing resources through international cooperation wherever possible.

  14. 44th Aerospace Mechanisms Symposium

    NASA Technical Reports Server (NTRS)

    Boesiger, Edward A. (Compiler)

    2018-01-01

    The Aerospace Mechanisms Symposium (AMS) provides a unique forum for those active in the design, production and use of aerospace mechanisms. A major focus is the reporting of problems and solutions associated with the development and flight certification of new mechanisms.

  15. Aerospace Activities and Language Development

    ERIC Educational Resources Information Center

    Jones, Robert M.; Piper, Martha

    1975-01-01

    Describes how science activities can be used to stimulate language development in the elementary grades. Two aerospace activities are described involving liquid nitrogen and the launching of a weather balloon which integrate aerospace interests into the development of language skills. (BR)

  16. Acting Administrator Lightfoot Visits Ball Aerospace

    NASA Image and Video Library

    2017-04-06

    Acting NASA Deputy Administrator Lesa Roe, second from left, and acting NASA Administrator Robert Lightfoot, second from left, are seen with Mike Gazarik, vice president of Engineering at Ball Aerospace, left and Shawn Conley, test operations manager at Ball Aerospace, left, in front of the large semi-anechoic chamber, Thursday, April 6, 2017 during a visit to Ball Aerospace in Boulder, Colo. Photo Credit: (NASA/Joel Kowsky)

  17. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 19: Computer and information technology and aerospace knowledge diffusion

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Kennedy, John M.; Barclay, Rebecca O.; Bishop, Ann P.

    1992-01-01

    To remain a world leader in aerospace, the US must improve and maintain the professional competency of its engineers and scientists, increase the research and development (R&D) knowledge base, improve productivity, and maximize the integration of recent technological developments into the R&D process. How well these objectives are met, and at what cost, depends on a variety of factors, but largely on the ability of US aerospace engineers and scientists to acquire and process the results of federally funded R&D. The Federal Government's commitment to high speed computing and networking systems presupposes that computer and information technology will play a major role in the aerospace knowledge diffusion process. However, we know little about information technology needs, uses, and problems within the aerospace knowledge diffusion process. The use of computer and information technology by US aerospace engineers and scientists in academia, government, and industry is reported.

  18. State of the Art in LP-WAN Solutions for Industrial IoT Services

    PubMed Central

    Sanchez-Iborra, Ramon; Cano, Maria-Dolores

    2016-01-01

    The emergence of low-cost connected devices is enabling a new wave of sensorization services. These services can be highly leveraged in industrial applications. However, the technologies employed so far for managing this kind of system do not fully cover the strict requirements of industrial networks, especially those regarding energy efficiency. In this article a novel paradigm, called Low-Power Wide Area Networking (LP-WAN), is explored. By means of a cellular-type architecture, LP-WAN–based solutions aim at fulfilling the reliability and efficiency challenges posed by long-term industrial networks. Thus, the most prominent LP-WAN solutions are reviewed, identifying and discussing the pros and cons of each of them. The focus is also on examining the current deployment state of these platforms in Spain. Although LP-WAN systems are at early stages of development, they represent a promising alternative for boosting future industrial IIoT (Industrial Internet of Things) networks and services. PMID:27196909

  19. State of the Art in LP-WAN Solutions for Industrial IoT Services.

    PubMed

    Sanchez-Iborra, Ramon; Cano, Maria-Dolores

    2016-05-17

    The emergence of low-cost connected devices is enabling a new wave of sensorization services. These services can be highly leveraged in industrial applications. However, the technologies employed so far for managing this kind of system do not fully cover the strict requirements of industrial networks, especially those regarding energy efficiency. In this article a novel paradigm, called Low-Power Wide Area Networking (LP-WAN), is explored. By means of a cellular-type architecture, LP-WAN-based solutions aim at fulfilling the reliability and efficiency challenges posed by long-term industrial networks. Thus, the most prominent LP-WAN solutions are reviewed, identifying and discussing the pros and cons of each of them. The focus is also on examining the current deployment state of these platforms in Spain. Although LP-WAN systems are at early stages of development, they represent a promising alternative for boosting future industrial IIoT (Industrial Internet of Things) networks and services.

  20. NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 45; The Technical Communications Practices of US Aerospace Engineers and Scientists: Results of the Phase 3 US Aerospace Engineering Educators Survey

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.

    1996-01-01

    The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. Little is also known about the intermediary-based system that is used to transfer the results of federally funded R&D to the U.S. aerospace industry. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports, present a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis the technical communication practices of U.S. aerospace engineers and scientists who were members of the American Institute of Aeronautics and Astronautics (AIAA) and identified themselves as educators.

  1. 76 FR 67017 - Praesidian Capital Opportunity Fund III, LP License No. 02/02-0647; Notice Seeking Exemption...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ... II, LP, Associate of Praesidian Capital Opportunity Fund III, LP, holds a debt investment and warrant... SMALL BUSINESS ADMINISTRATION Praesidian Capital Opportunity Fund III, LP License No. 02/02- 0647; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest...

  2. 77 FR 50492 - Notice of Petition for Declaratory Order; Shell Pipeline Company LP

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-21

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. OR12-23-000] Notice of Petition for Declaratory Order; Shell Pipeline Company LP Take notice that on August 10, 2012, pursuant to Rule 207(a)(2), Shell Pipeline Company LP submitted a petition requesting that the Federal Energy...

  3. 77 FR 21764 - Shell Pipeline Company LP; Notice of Petition for Declaratory Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-11

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. OR12-11-000] Shell Pipeline Company LP; Notice of Petition for Declaratory Order Take notice that on March 30, 2012, pursuant to Rule 207(a)(2), Shell Pipeline Company LP (SPLC) submitted a petition requesting that the Federal Energy...

  4. 76 FR 63294 - Chevron Products Company v. SFPP, L.P. ; Notice of Complaint

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. OR12-1-000; Docket No. IS11-585-000] Chevron Products Company v. SFPP, L.P. ; Notice of Complaint Take notice that on October 5.... 13(1), Chevron Products Company (Complainants) filed a complaint against SFPP, L.P. (Respondent...

  5. 77 FR 36527 - Enstor Katy Storage and Transportation, L.P.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-19

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR12-29-000] Enstor Katy Storage and Transportation, L.P.; Notice of Filing Take notice that on June 12, 2012, Enstor Katy Storage and Transportation, L.P. filed to revise its Statement of Operating Conditions to correct, update, and...

  6. 75 FR 37785 - Crosstex North Texas Pipeline, L.P.; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-30

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-39-000] Crosstex North Texas Pipeline, L.P.; Notice of Baseline Filing June 23, 2010. Take notice that on June 21, 2010, Crosstex North Texas Pipeline, L.P. submitted a baseline filing of its FERC Operating Statement for...

  7. 75 FR 33799 - Enbridge Pipelines (North Texas) L.P.; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-29-000] Enbridge Pipelines (North Texas) L.P.; Notice of Baseline Filing June 8, 2010. Take notice that on June 4, 2010, Enbridge Pipelines (North Texas) L.P. submitted a baseline filing of its Statement of Operating Conditions...

  8. 75 FR 61462 - Enbridge Pipelines (North Texas) L.P.; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-29-002] Enbridge Pipelines (North Texas) L.P.; Notice of Baseline Filing September 29, 2010. Take notice that on September 27, 2010, Enbridge Pipelines (North Texas) L.P. submitted a revised baseline filing of its Statement of...

  9. 75 FR 69063 - Enbridge Pipelines (North Texas) L.P.; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-29-003] Enbridge Pipelines (North Texas) L.P.; Notice of Baseline Filing November 4, 2010. Take notice that on November 3, 2010, Enbridge Pipelines (North Texas) L.P. submitted a revised baseline filing of its Statement of...

  10. Frontier Aerospace Opportunities

    NASA Technical Reports Server (NTRS)

    Bushnell, Dennis M.

    2014-01-01

    Discussion and suggested applications of the many ongoing technology opportunities for aerospace products and missions, resulting in often revolutionary capabilities. The, at this point largely unexamined, plethora of possibilities going forward, a subset of which is discussed, could literally reinvent aerospace but requires triage of many possibilities. Such initial upfront homework would lengthen the Research and Development (R&D) time frame but could greatly enhance the affordability and performance of the evolved products and capabilities. Structural nanotubes and exotic energetics along with some unique systems approaches are particularly compelling.

  11. Unification: An international aerospace information issue

    NASA Technical Reports Server (NTRS)

    Cotter, Gladys A.; Lahr, Thomas F.

    1991-01-01

    Science and technology projects are becoming more and more international and interdisciplinary. Other parts of the world, notably Europe, are increasingly powerful players in the aerospace business. This change has led to the development of various aerospace information initiatives in other countries. With scarce resources in all areas of government and industry, the NASA STI Program is reviewing its current acquisition and exchange practices and policies to factor in the changing requirements and new opportunities within the international community. Current NASA goals and activities are reviewed with a view toward developing a scenario for establishing an international aerospace data base, maintaining compatibility among national aerospace information systems, eliminating duplication of effort, and sharing resources through international cooperation wherever possible.

  12. Unification - An international aerospace information opportunity

    NASA Technical Reports Server (NTRS)

    Cotter, Gladys A.; Lahr, Thomas F.

    1992-01-01

    Science and technology projects are becoming more and more international and interdisciplinary. Other parts of the world, notably Europe, are increasingly powerful players in the aerospace industry. This change has led to the development of various aerospace information initiatives in other countries. With scarce resources in all areas of government and industry, the NASA STI Program is reviewing its current acquisition and exchange practices and policies to factor in the changing requirements and new opportunities within the international community. Current NASA goals and activities are reviewed with a new view toward developing a scenario for establishing an international aerospace database, maintaining compatibility among national aerospace information systems, eliminating duplication of effort, and sharing resources through international cooperation wherever possible.

  13. Unification: An international aerospace information opportunity

    NASA Technical Reports Server (NTRS)

    Cotter, Gladys A.; Lahr, Thomas F.; Carroll, Bonnie C.

    1992-01-01

    Science and technology projects are becoming more and more international and interdisciplinary. Other parts of the world, notably Europe, are increasingly powerful players in the aerospace industry. This change has led to the development of various aerospace information initiatives in other countries. With scarce resources in all areas of government and industry, the NASA STI Program is reviewing its current acquisition and exchange practices and policies to factor in the changing requirements and new opportunities within the international community. Current NASA goals and activities are reviewed with a new view toward developing a scenario for establishing an international aerospace database, maintaining compatibility among national aerospace information systems, eliminating duplication of effort, and sharing resources through international cooperation wherever possible.

  14. Limitless Horizons: Careers in Aerospace.

    ERIC Educational Resources Information Center

    Lewis, Mary H.

    This is a manual for acquainting students with pertinent information relating to career choices in aerospace science, engineering, and technology. The first chapter presents information about the aerospace industry by describing disciplines typical of this industry. The National Aeronautics and Space Administration's (NASA) classification system…

  15. Mass spectrometry of aerospace materials

    NASA Technical Reports Server (NTRS)

    Colony, J. A.

    1976-01-01

    Mass spectrometry is used for chemical analysis of aerospace materials and contaminants. Years of analytical aerospace experience have resulted in the development of specialized techniques of sampling and analysis which are required in order to optimize results. This work has resulted in the evolution of a hybrid method of indexing mass spectra which include both the largest peaks and the structurally significant peaks in a concise format. With this system, a library of mass spectra of aerospace materials was assembled, including the materials responsible for 80 to 90 percent of the contamination problems at Goddard Space Flight Center during the past several years.

  16. Aeromedical solutions for aerospace safety.

    PubMed

    Kapoor, Pawan; Gaur, Deepak

    2017-10-01

    All facets of activity in the speciality of Aviation Medicine are essentially aimed at enhancing aerospace safety. This paper highlights some innovative changes brought about by Aerospace Medicine in the three major fields of the speciality namely, medical evaluation, aeromedical training and research. Based on lab and field studies, military aircrew are now permitted flying with Modifinil as 'Go' Pill and Zolpidem as 'No-Go' Pill during sustained operations. Several other drugs for disabilities like Hypertension and CAD are now permitted for aviators. Comprehensive revision of policy permitting early return to flying is an on-going process. OPRAM courses for all three streams of aircrew in IAF have contributed to reduce aircraft accident rates. Human Engineering Consultancy and expert advice is provided by specialists at IAM as well as those in the field. In future, the country needs to provide better post-service opportunities to aerospace medicine specialists. This, in turn, will attract bright young minds to the specialty. The ISRO Humanin-Space programme will be an exciting challenge for all in this unique field. Aerospace Medicine continues to provide aerospace safety solutions to the IAF and the aviation industry. The nation needs to continue to utilize and support this specialty.

  17. Recent advances in the development of aerospace materials

    NASA Astrophysics Data System (ADS)

    Zhang, Xuesong; Chen, Yongjun; Hu, Junling

    2018-02-01

    In recent years, much progress has been made on the development of aerospace materials for structural and engine applications. Alloys, such as Al-based alloys, Mg-based alloys, Ti-based alloys, and Ni-based alloys, are developed for aerospace industry with outstanding advantages. Composite materials, the innovative materials, are taking more and more important roles in aircrafts. However, recent aerospace materials still face some major challenges, such as insufficient mechanical properties, fretting wear, stress corrosion cracking, and corrosion. Consequently, extensive studies have been conducted to develop the next generation aerospace materials with superior mechanical performance and corrosion resistance to achieve improvements in both performance and life cycle cost. This review focuses on the following topics: (1) materials requirements in design of aircraft structures and engines, (2) recent advances in the development of aerospace materials, (3) challenges faced by recent aerospace materials, and (4) future trends in aerospace materials.

  18. 32 CFR 705.30 - Aerospace Education Workshop.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 5 2012-07-01 2012-07-01 false Aerospace Education Workshop. 705.30 Section 705... REGULATIONS AND OFFICIAL RECORDS PUBLIC AFFAIRS REGULATIONS § 705.30 Aerospace Education Workshop. (a) This... of Naval Operations has cognizance of all assistance provided by the Navy to all Aerospace Education...

  19. 32 CFR 705.30 - Aerospace Education Workshop.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 5 2014-07-01 2014-07-01 false Aerospace Education Workshop. 705.30 Section 705... REGULATIONS AND OFFICIAL RECORDS PUBLIC AFFAIRS REGULATIONS § 705.30 Aerospace Education Workshop. (a) This... of Naval Operations has cognizance of all assistance provided by the Navy to all Aerospace Education...

  20. 32 CFR 705.30 - Aerospace Education Workshop.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 5 2013-07-01 2013-07-01 false Aerospace Education Workshop. 705.30 Section 705... REGULATIONS AND OFFICIAL RECORDS PUBLIC AFFAIRS REGULATIONS § 705.30 Aerospace Education Workshop. (a) This... of Naval Operations has cognizance of all assistance provided by the Navy to all Aerospace Education...

  1. 76 FR 29234 - Texas Eastern Transmission, LP; Notice of Request Under Blanket Authorization

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-20

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP11-477-000] Texas Eastern Transmission, LP; Notice of Request Under Blanket Authorization Take notice that on May 10, 2011 Texas Eastern Transmission, LP (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056, filed in Docket No. CP11-477-000...

  2. 77 FR 68118 - TexStar Transmission, LP; Notice of Petition for Rate Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-15

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [ Docket No. PR13-4-000] TexStar Transmission, LP; Notice of Petition for Rate Approval Take notice that on November 2, 2012, TexStar Transmission, LP (TexStar) filed a Petition for Rate Approval pursuant to 284.123(b)(2) of the Commissions...

  3. 77 FR 13593 - PowerSmith Cogeneration Project, LP; Notice of Request for Waiver

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-07

    ...] PowerSmith Cogeneration Project, LP; Notice of Request for Waiver Take notice that on February 27, 2012... CFR 292.205(c), PowerSmith Cogeneration Project, LP (PowerSmith) filed a Request for Waiver, for... Regulations for the topping- cycle cogeneration facility owned and operated by PowerSmith located in Oklahoma...

  4. The Apo(a) gene is the major determinant of variation in plasma Lp(a) levels in African Americans.

    PubMed Central

    Mooser, V; Scheer, D; Marcovina, S M; Wang, J; Guerra, R; Cohen, J; Hobbs, H H

    1997-01-01

    The distributions of plasma lipoprotein(a), or Lp(a), levels differ significantly among ethnic groups. Individuals of African descent have a two- to threefold higher mean plasma level of Lp(a) than either Caucasians or Orientals. In Caucasians, variation in the plasma Lp(a) levels has been shown to be largely determined by sequence differences at the apo(a) locus, but little is known about either the genetic architecture of plasma Lp(a) levels in Africans or why they have higher levels of plasma Lp(a). In this paper we analyze the plasma Lp(a) levels of 257 sibling pairs from 49 independent African American families. The plasma Lp(a) levels were much more similar in the sibling pairs who inherited both apo(a) alleles identical by descent (IBD) (r = .85) than in those that shared one (r = .48) or no (r = .22) parental apo(a) alleles in common. On the basis of these findings, it was estimated that 78% of the variation in plasma Lp(a) levels in African Americans is attributable to polymorphism at either the apo(a) locus or sequences closely linked to it. Thus, the apo(a) locus is the major determinant of variation in plasma Lp(a) levels in African Americans, as well as in Caucasians. No molecular evidence was found for a common "high-expressing" apo(a) allele in the African Americans. We propose that the higher plasma levels of Lp(a) in Africans are likely due to a yet-to-be-identified trans-acting factor(s) that causes an increase in the rate of secretion of apo(a) or a decrease in its catabolism. PMID:9311746

  5. Technical communications in aerospace - An analysis of the practices reported by U.S. and European aerospace engineers and scientists

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.; Glassman, Myron

    1990-01-01

    The flow of scientific and technical information (STI) at the individual, organizational, national, and international levels is studied. The responses of U.S and European aerospace engineers and scientists to questionnaires concerning technical communications in aerospace are examined. Particular attention is given to the means used to communicate information and the social system of the aerospace knowledge diffusion process. Demographic data about the survey respondents are provided. The methods used to communicate technical data and the sources utilized to solve technical problems are described. The importance of technical writing skills and the use of computer technology in the aerospace field are discussed. The derived data are useful for R&D and information managers in order to improve access to and utilization of aerospace STI.

  6. NASA Aerospace Flight Battery Systems Program Update

    NASA Technical Reports Server (NTRS)

    Manzo, Michelle; ODonnell, Patricia

    1997-01-01

    The objectives of NASA's Aerospace Flight Battery Systems Program is to: develop, maintain and provide tools for the validation and assessment of aerospace battery technologies; accelerate the readiness of technology advances and provide infusion paths for emerging technologies; provide NASA projects with the required database and validation guidelines for technology selection of hardware and processes relating to aerospace batteries; disseminate validation and assessment tools, quality assurance, reliability, and availability information to the NASA and aerospace battery communities; and ensure that safe, reliable batteries are available for NASA's future missions.

  7. 76 FR 28026 - TransCanada Keystone Pipeline, LP; Notice of Request for Waiver

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. OR11-7-000] TransCanada Keystone Pipeline, LP; Notice of Request for Waiver Take notice that on May 2, 2011, TransCanada Keystone Pipeline, LP (TransCanada Keystone) filed a request for waiver of the requirement in 18 CFR 342.4(c) that...

  8. 76 FR 63918 - ConocoPhillips Company v. SFPP, L.P.; Notice of Complaint

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-14

    ... Company v. SFPP, L.P.; Notice of Complaint Take notice that on October 5, 2011, pursuant to Rule 206 of... Company (Complainant) filed a formal complaint against SFPP, L.P. (Respondent), challenging the lawfulness...: 5 p.m. Eastern Time on October 25, 2011. Dated: October 6, 2011. Kimberly D. Bose, Secretary. [FR...

  9. Aerospace Training. Washington's Community and Technical Colleges

    ERIC Educational Resources Information Center

    Washington State Board for Community and Technical Colleges, 2014

    2014-01-01

    Aerospace is an economic powerhouse that generates jobs and fuels our economy. Washington's community and technical colleges produce the world-class employees needed to keep it that way. With about 1,250 aerospace-related firms employing more than 94,000 workers, Washington has the largest concentration of aerospace expertise in the nation. To…

  10. Single-Nucleotide Polymorphisms in LPA Explain Most of the Ancestry-Specific Variation in Lp(a) Levels in African Americans

    PubMed Central

    Lawson, Kim; Kao, W. H. Linda; Reich, David; Tandon, Arti; Akylbekova, Ermeg; Patterson, Nick; Mosley, Thomas H.; Boerwinkle, Eric; Taylor, Herman A.

    2011-01-01

    Lipoprotein(a) (Lp(a)) is an important causal cardiovascular risk factor, with serum Lp(a) levels predicting atherosclerotic heart disease and genetic determinants of Lp(a) levels showing association with myocardial infarction. Lp(a) levels vary widely between populations, with African-derived populations having nearly 2-fold higher Lp(a) levels than European Americans. We investigated the genetic basis of this difference in 4464 African Americans from the Jackson Heart Study (JHS) using a panel of up to 1447 ancestry informative markers, allowing us to accurately estimate the African ancestry proportion of each individual at each position in the genome. In an unbiased genome-wide admixture scan for frequency-differentiated genetic determinants of Lp(a) level, we found a convincing peak (LOD = 13.6) at 6q25.3, which spans the LPA locus. Dense fine-mapping of the LPA locus identified a number of strongly associated, common biallelic SNPs, a subset of which can account for up to 7% of the variation in Lp(a) level, as well as >70% of the African-European population differences in Lp(a) level. We replicated the association of the most strongly associated SNP, rs9457951 (p = 6×10−22, 27% change in Lp(a) per allele, ∼5% of Lp(a) variance explained in JHS), in 1,726 African Americans from the Dallas Heart Study and found an even stronger association after adjustment for the kringle(IV) repeat copy number. Despite the strong association with Lp(a) levels, we find no association of any LPA SNP with incident coronary heart disease in 3,225 African Americans from the Atherosclerosis Risk in Communities Study. PMID:21283670

  11. Aerospace Education for the Melting Pot.

    ERIC Educational Resources Information Center

    Joels, Kerry M.

    1979-01-01

    Aerospace education is eminently suited to provide a framework for multicultural education. Effective programs accommodating minorities' frames of reference to the rapidly developing disciplines of aerospace studies have been developed. (RE)

  12. Aerospace Education and the Elementary Teacher

    ERIC Educational Resources Information Center

    Jones, Robert M.

    1978-01-01

    This articles attempts to stimulate otherwise reluctant school teachers to involve aerospace education in their content repertoire. Suggestions are made to aid the teacher in getting started with aerospace education. (MDR)

  13. 75 FR 27774 - Eagle Rock Desoto Pipeline, L.P.; Notice of Rate Election

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-18

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-22-000] Eagle Rock Desoto Pipeline, L.P.; Notice of Rate Election May 11, 2010. Take notice that on May 3, 2010, Eagle Rock Desoto Pipeline, L.P., (Desoto) filed a Notice of Rate Election pursuant to section 284.123(b)(1)(ii) of...

  14. 75 FR 69428 - Enbridge Pipelines (North Texas) L.P.; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-12

    ... Pipelines (North Texas) L.P.; Notice of Baseline Filing November 4, 2010. Take notice that on November 3, 2010, Enbridge Pipelines (North Texas) L.P. submitted a revised baseline filing of its Statement of... , or call (866) 208-3676 (toll free). For TTY, call (202) 502-8659. Comment Date: 5 p.m. Eastern Time...

  15. 77 FR 63813 - Sunoco Pipeline L.P.; Notice of Petition for Declaratory Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... L.P.; Notice of Petition for Declaratory Order Take notice that on October 9, 2012, pursuant to Rule... Pipeline L.P. (``SPLP''), filed a petition seeking a declaratory order approving priority service, the... (18 CFR 385.211 and 385.214) on or before 5:00 p.m. Eastern time on the specified comment date...

  16. 78 FR 18973 - Bridgeline Holdings, L.P.; Notice of Petition for Rate Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ... Holdings, L.P.; Notice of Petition for Rate Approval Take notice that on February 28, 2013, as supplemented on March 12, 2013, Bridgeline Holdings, L.P. filed for approval of rates for transportation services... TTY, call (202) 502-8659. Comment Date: 5:00 p.m. Eastern Time on Monday, April 1, 2013. Dated: March...

  17. 75 FR 49917 - Enbridge Pipelines (North Texas) L.P.; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-16

    ... Pipelines (North Texas) L.P.; Notice of Baseline Filing August 6, 2010. Take notice that on July 29, 2010, Enbridge Pipelines (North Texas) L.P. submitted a revised baseline filing of its Statement of Operating... (toll free). For TTY, call (202) 502-8659. Comment Date: 5 p.m. Eastern Time on Monday, August 16, 2010...

  18. Metabolic and anthropometric determinants of serum Lp(a) concentrations and Apo(a) polymorphism in a healthy Arab population.

    PubMed

    Akanji, A O; al-Shayji, I A; Kumar, P

    1999-08-01

    Blood lipoprotein(a) Lp(a) concentrations are an important risk factor for atherosclerosis. The basis for this atherogenic property of Lp(a) and the factors that influence its cross-population levels, however, remain poorly understood. To investigate the relationship between serum Lp(a) and metabolic and anthropometric parameters in a healthy Kuwaiti population. Cross-sectional study. 177 (72 male, 105 female) randomly recruited healthy Kuwait Arabs aged 17-60 y Metabolic parameters in serum: Lp(a), apo(a) phenotypes, lipids and lipoproteins, glucose and urate. Anthropometric parameters: body mass index (BMI) and waist:hip-ratio (WHR). The distribution of Lp(a) concentrations was positively skewed (median 153 mg/l, range 0-1086). Women had higher concentrations-(194, 0-1086) than men (117, 0-779), P = 0.069. Lp(a) and insulin concentrations were significantly higher when the men and women were obese. In all subjects, there were significant correlations between Lp(a) and BMI (r = 0.23), total cholesterol (TC) (r = 0.17) and LDL (r = 0.20). Lp(a) correlated only with glucose in men (r = 0.28). In women it correlated with age (r = 0.20), BMI (r = 0.30), BP (r = 0.20), TC (r = 0.20) and LDL (r = 0.26). Multivariate analyses confirmed BMI and low-density lipoprotein (LDL) as the significant determinants of serum Lp(a). On apo (a) phenotyping, 114 (67%), 51 (30%) and 6 (4%) had single, double and null phenotypes respectively. The isoforms and their corresponding kringle IV repeat numbers were: F (14 repeats in 3%, mean Lp(a) 497 mg/l); S1 (19 repeats in 14%, mean 245 mg/l); S2 (23 repeats in 16%, mean 264 mg/l); S3 (27 repeats in 35%, mean 236 mg/l); and S4 (35 repeats in 28%, mean 235 mg/l). The results from the Kuwaiti population studied suggest that: (1) serum Lp(a) concentrations and distribution are similar to the pattern in Caucasians and Asians but not African-Americans or Africans; (2) serum Lp(a) is variably influenced by BMI and LDL--the impact of either factor

  19. Limitless Horizons. Careers in Aerospace

    NASA Technical Reports Server (NTRS)

    Lewis, M. H.

    1980-01-01

    A manual is presented for use by counselors in career guidance programs. Pertinent information is provided on choices open in aerospace sciences, engineering, and technology. Accredited institutions awarding degrees in pertinent areas are listed as well as additional sources of aerospace career information. NASA's role and fields of interest are emphasized.

  20. 76 FR 58776 - U.S. Aerospace Supplier & Investment Mission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-22

    ... DEPARTMENT OF COMMERCE International Trade Administration U.S. Aerospace Supplier & Investment... organizing a U.S. Aerospace Supplier & Investment Mission to Montreal, Canada, May 6-9, 2012. This aerospace.... Participation Requirements All parties interested in participating in the U.S. aerospace trade and investment...

  1. Comparative genome analysis of Lactobacillus plantarum GB-LP3 provides candidates of survival-related genetic factors.

    PubMed

    Jeon, Soomin; Jung, Jaehoon; Kim, Kwondo; Yoo, DongAhn; Lee, Chanho; Kang, Jungsun; Cho, Kyungjin; Kang, Dae-Kyung; Kwak, Woori; Yoon, Sook Hee; Kim, Heebal; Cho, Seoae

    2017-09-01

    Lactobacillus plantarum is found in various environmental niches such as in the gastrointestinal tract of an animal host or a fermented food. This species isolated from a certain environment is known to possess a variety of properties according to inhabited environment's adaptation. However, a causal relationship of a genetic factor and phenotype affected by a specific environment has not been systematically comprehended. L. plantarum GB-LP3 strain was isolated from Korean traditional fermented vegetable and the whole genome of GB-LP3 was sequenced. Comparative genome analysis of GB-LP3, with other 14 L. plantarum strains, was conducted. In addition, genomic island regions were investigated. The assembled whole GB-LP3 genome contained a single circular chromosome of 3,206,111bp with the GC content of 44.7%. In the phylogenetic tree analysis, GB-LP3 was in the closest distance from ZJ316. The genomes of GB-LP3 and ZJ316 have the high level of synteny. Functional genes that are related to prophage, bacteriocin, and quorum sensing were found through comparative genomic analysis with ZJ316 and investigation of genomic islands. dN/dS analysis identified that the gene coding for phosphonate ABC transporter ATP-binding protein is evolutionarily accelerated in GB-LP3. Our study found that potential candidate genes that are affected by environmental adaptation in Korea traditional fermented vegetable. Copyright © 2017. Published by Elsevier B.V.

  2. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 47: The value of computer networks in aerospace

    NASA Technical Reports Server (NTRS)

    Bishop, Ann Peterson; Pinelli, Thomas E.

    1995-01-01

    This paper presents data on the value of computer networks that were obtained from a national survey of 2000 aerospace engineers that was conducted in 1993. Survey respondents reported the extent to which they used computer networks in their work and communication and offered their assessments of the value of various network types and applications. They also provided information about the positive impacts of networks on their work, which presents another perspective on value. Finally, aerospace engineers' recommendations on network implementation present suggestions for increasing the value of computer networks within aerospace organizations.

  3. Differential expression of Lp-PLA2 in obesity and type 2 diabetes and the influence of lipids.

    PubMed

    Jackisch, Laura; Kumsaiyai, Warunee; Moore, Jonathan D; Al-Daghri, Nasser; Kyrou, Ioannis; Barber, Thomas M; Randeva, Harpal; Kumar, Sudhesh; Tripathi, Gyanendra; McTernan, Philip G

    2018-05-01

    Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a circulatory macrophage-derived factor that increases with obesity and leads to a higher risk of cardiovascular disease (CVD). Despite this, its role in adipose tissue and the adipocyte is unknown. Therefore, the aims of this study were to clarify the expression of Lp-PLA2 in relation to different adipose tissue depots and type 2 diabetes, and ascertain whether markers of obesity and type 2 diabetes correlate with circulating Lp-PLA2. A final aim was to evaluate the effect of cholesterol on cellular Lp-PLA2 in an in vitro adipocyte model. Analysis of anthropometric and biochemical variables from a cohort of lean (age 44.4 ± 6.2 years; BMI 22.15 ± 1.8 kg/m 2 , n = 23), overweight (age 45.4 ± 12.3 years; BMI 26.99 ± 1.5 kg/m 2 , n = 24), obese (age 49.0 ± 9.1 years; BMI 33.74 ± 3.3 kg/m 2 , n = 32) and type 2 diabetic women (age 53.0 ± 6.13 years; BMI 35.08 ± 8.6 kg/m 2 , n = 35), as part of an ethically approved study. Gene and protein expression of PLA2 and its isoforms were assessed in adipose tissue samples, with serum analysis undertaken to assess circulating Lp-PLA2 and its association with cardiometabolic risk markers. A human adipocyte cell model, Chub-S7, was used to address the intracellular change in Lp-PLA2 in adipocytes. Lp-PLA2 and calcium-independent PLA2 (iPLA2) isoforms were altered by adiposity, as shown by microarray analysis (p < 0.05). Type 2 diabetes status was also observed to significantly alter gene and protein levels of Lp-PLA2 in abdominal subcutaneous (AbdSc) (p < 0.01), but not omental, adipose tissue. Furthermore, multivariate stepwise regression analysis of circulating Lp-PLA2 and metabolic markers revealed that the greatest predictor of Lp-PLA2 in non-diabetic individuals was LDL-cholesterol (p = 0.004). Additionally, in people with type 2 diabetes, oxidised LDL (oxLDL), triacylglycerols and HDL

  4. Long Period (LP) volcanic earthquake source location at Merapi volcano by using dense array technics

    NASA Astrophysics Data System (ADS)

    Metaxian, Jean Philippe; Budi Santoso, Agus; Laurin, Antoine; Subandriyo, Subandriyo; Widyoyudo, Wiku; Arshab, Ghofar

    2015-04-01

    Since 2010, Merapi shows unusual activity compared to last decades. Powerful phreatic explosions are observed; some of them are preceded by LP signals. In the literature, LP seismicity is thought to be originated within the fluid, and therefore to be representative of the pressurization state of the volcano plumbing system. Another model suggests that LP events are caused by slow, quasi-brittle, low stress-drop failure driven by transient upper-edifice deformations. Knowledge of the spatial distribution of LP events is fundamental for better understanding the physical processes occurring in the conduit, as well as for the monitoring and the improvement of eruption forecasting. LP events recorded at Merapi have a spectral content dominated by frequencies between 0.8 and 3 Hz. To locate the source of these events, we installed a seismic antenna composed of 4 broadband CMG-6TD Güralp stations. This network has an aperture of 300 m. It is located on the site of Pasarbubar, between 500 and 800 m from the crater rim. Two multi-parameter stations (seismic, tiltmeter, S-P) located in the same area, equipped with broadband CMG-40T Güralp sensors may also be used to complete the data of the antenna. The source of LP events is located by using different approaches. In the first one, we used a method based on the measurement of the time delays between the early beginnings of LP events for each array receiver. The observed differences of time delays obtained for each pair of receivers are compared to theoretical values calculated from the travel times computed between grid nodes, which are positioned in the structure, and each receiver. In a second approach, we estimate the slowness vector by using MUSIC algorithm applied to 3-components data. From the slowness vector, we deduce the back-azimuth and the incident angle, which give an estimation of LP source depth in the conduit. This work is part of the Domerapi project funded by French Agence Nationale de la Recherche (https

  5. An alternative physiological role for the EmhABC efflux pump in Pseudomonas fluorescens cLP6a

    PubMed Central

    2011-01-01

    Background Efflux pumps belonging to the resistance-nodulation-division (RND) superfamily in bacteria are involved in antibiotic resistance and solvent tolerance but have an unknown physiological role. EmhABC, a RND-type efflux pump in Pseudomonas fluorescens strain cLP6a, extrudes hydrophobic antibiotics, dyes and polycyclic aromatic hydrocarbons including phenanthrene. The effects of physico-chemical factors such as temperature or antibiotics on the activity and expression of EmhABC were determined in order to deduce its physiological role(s) in strain cLP6a in comparison to the emhB disruptant strain, cLP6a-1. Results Efflux assays conducted with 14C-phenanthrene showed that EmhABC activity is affected by incubation temperature. Increased phenanthrene efflux was measured in cLP6a cells grown at 10°C and decreased efflux was observed at 35°C compared with cells grown at the optimum temperature of 28°C. Membrane fatty acids in cLP6a cells were substantially altered by changes in growth temperature and in the presence of tetracycline. Changed membrane fatty acids and increased membrane permeability were associated with ~30-fold increased expression of emhABC in cLP6a cells grown at 35°C, and with increased extracellular free fatty acids. Growth of P. fluorescens cLP6a at supra-optimal temperature was enhanced by the presence of EmhABC compared to strain cLP6a-1. Conclusions Combined, these observations suggest that the EmhABC efflux pump may be involved in the management of membrane stress effects such as those due to unfavourable incubation temperatures. Efflux of fatty acids replaced as a result of membrane damage or phospholipid turnover may be the primary physiological role of the EmhABC efflux pump in P. fluorescens cLP6a. PMID:22085438

  6. Transcriptome analysis of the epidermis of the purple quail-like (q-lp) mutant of silkworm, Bombyx mori.

    PubMed

    Wang, Pingyang; Qiu, Zhiyong; Xia, Dingguo; Tang, Shunming; Shen, Xingjia; Zhao, Qiaoling

    2017-01-01

    A new purple quail-like (q-lp) mutant found from the plain silkworm strain 932VR has pigment dots on the epidermis similar to the pigment mutant quail (q). In addition, q-lp mutant larvae are inactive, consume little and grow slowly, with a high death rate and other developmental abnormalities. Pigmentation of the silkworm epidermis consists of melanin, ommochrome and pteridine. Silkworm development is regulated by ecdysone and juvenile hormone. In this study, we performed RNA-Seq on the epidermis of the q-lp mutant in the 4th instar during molting, with 932VR serving as the control. The results showed 515 differentially expressed genes, of which 234 were upregulated and 281 downregulated in q-lp. BLASTGO analysis indicated that the downregulated genes mainly encode protein-binding proteins, membrane components, oxidation/reduction enzymes, and proteolytic enzymes, whereas the upregulated genes largely encode cuticle structural constituents, membrane components, transport related proteins, and protein-binding proteins. Quantitative reverse transcription PCR was used to verify the accuracy of the RNA-Seq data, focusing on key genes for biosynthesis of the three pigments and chitin as well as genes encoding cuticular proteins and several related nuclear receptors, which are thought to play key roles in the q-lp mutant. We drew three conclusions based on the results: 1) melanin, ommochrome and pteridine pigments are all increased in the q-lp mutant; 2) more cuticle proteins are expressed in q-lp than in 932VR, and the number of upregulated cuticular genes is significantly greater than downregulated genes; 3) the downstream pathway regulated by ecdysone is blocked in the q-lp mutant. Our research findings lay the foundation for further research on the developmental changes responsible for the q-lp mutant.

  7. Optical Information Processing for Aerospace Applications

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Current research in optical processing is reviewed. Its role in future aerospace systems is determined. The development of optical devices and components demonstrates that system concepts can be implemented in practical aerospace configurations.

  8. Acting Administrator Lightfoot Visits Ball Aerospace

    NASA Image and Video Library

    2017-04-06

    Acting NASA Deputy Administrator Lesa Roe, right, speaks with Rob Strain, president of Ball Aerospace, Thursday, April 6, 2017 during a visit to Ball Aerospace in Boulder, Colo. Photo Credit: (NASA/Joel Kowsky)

  9. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 5: Aerospace librarians and technical information specialists as information intermediaries: A report of phase 2 activities of the NASA/DOD Aerospace Knowledge Diffusion Research Project

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Kennedy, John M.

    1990-01-01

    The objective of the NASA/DOD Aerospace Knowledge Diffusion Research Project is to provide descriptive and analytical data regarding the flow of scientific and technical information (STI) at the individual, organizational, national, and international levels, placing emphasis on the systems used to diffuse the results of federally funded aerospace STI. An overview of project assumptions, objectives, and design is presented and preliminary results of the phase 2 aerospace library survey are summarized. Phase 2 addressed aerospace knowledge transfer and use within the larger social system and focused on the flow of aerospace STI in government and industry and the role of the information intermediary in knowledge transfer.

  10. 77 FR 2293 - AmeriGas Propane, L.P., AmeriGas Propane, Inc., Energy Transfer Partners, L.P., and Energy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-17

    ... GP in which AmeriGas proposed to acquire ETP's Heritage Propane business through the approximately $2..., Titan Energy Partner, L.P., and Titan Energy GP, L.L.C. ETP's Heritage Propane business includes Heritage Propane Express, an entity that is engaged in the business of preparing, filling, distributing and...

  11. Dual-LP11 mode 4×4 MIMO-OFDM transmission over a two-mode fiber.

    PubMed

    Al Amin, Abdullah; Li, An; Chen, Simin; Chen, Xi; Gao, Guanjun; Shieh, William

    2011-08-15

    We report successful transmission of dual-LP(11) mode (LP(11a) and LP(11b)), dual polarization coherent optical orthogonal frequency-division multiplexing (CO-OFDM) signals over two-mode fibers (TMF) using all-fiber mode converters. Mode converters based on mechanically induced long-period grating with better than 20 dB extinction ratios are realized and used for interfacing single-mode fiber transmitter and receivers to the TMF. We demonstrate that by using 4×4 MIMO-OFDM processing, the random coupling of the two LP(11) spatial modes can be successfully tracked and equalized with a one-tap frequency-domain equalizer. We achieve successful transmission of 35.3 Gb/s over 26-km two-mode fiber with less than 3 dB penalty. © 2011 Optical Society of America

  12. Civil Air Patrol and Aerospace Education

    ERIC Educational Resources Information Center

    Sorenson, John V.

    1972-01-01

    Aerospace education is a branch of general education concerned with communicating knowledge, imparting skills, and developing attitudes necessary to interpret aerospace activities and the total impact of air and space vehicles upon society. (Author)

  13. 78 FR 1265 - Aerospace Safety Advisory Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 13-001] Aerospace Safety Advisory Panel... Aeronautics and Space Administration announces a forthcoming meeting of the Aerospace Safety Advisory Panel..., Aerospace Safety Advisory Panel Executive Director, National Aeronautics and Space Administration...

  14. 76 FR 62455 - Aerospace Safety Advisory Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-07

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-088)] Aerospace Safety Advisory Panel... Aeronautics and Space Administration announces a forthcoming meeting of the Aerospace Safety Advisory Panel... Burch, Aerospace Safety Advisory Panel Administrative Officer, National Aeronautics and Space...

  15. The benzomorphan-based LP1 ligand is a suitable MOR/DOR agonist for chronic pain treatment.

    PubMed

    Pasquinucci, Lorella; Parenti, Carmela; Turnaturi, Rita; Aricò, Giuseppina; Marrazzo, Agostino; Prezzavento, Orazio; Ronsisvalle, Simone; Georgoussi, Zafiroula; Fourla, Danai-Dionysia; Scoto, Giovanna M; Ronsisvalle, Giuseppe

    2012-01-02

    Powerful analgesics relieve pain primarily through activating mu opioid receptor (MOR), but the long-term use of MOR agonists, such as morphine, is limited by the rapid development of tolerance. Recently, it has been observed that simultaneous stimulation of the delta opioid receptor (DOR) and MOR limits the incidence of tolerance induced by MOR agonists. 3-[(2R,6R,11R)-8-hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide (LP1) is a centrally acting agent with antinociceptive activity comparable to morphine and is able to bind and activate MOR and DOR. The aim of this work was to evaluate and compare the induction of tolerance to antinociceptive effects from treatment with LP1 and morphine. Here, we evaluated the pharmacological effects of LP1 administered at a dose of 4 mg/kg subcutaneously (s.c.) twice per day for 9 days to male Sprague-Dawley rats. In addition, the LP1 mechanism of action was assessed by measurement of LP1-induced [(35)S]GTPγS binding to the MOR and DOR. Data obtained from the radiant heat tail flick test showed that LP1 maintained its antinociceptive profile until the ninth day, while tolerance to morphine (10mg/kg s.c. twice per day) was observed on day 3. Moreover, LP1 significantly enhanced [(35)S]GTPγS binding in the membranes of HEK293 cells expressing either the MOR or the DOR. LP1 is a novel analgesic agent for chronic pain treatment, and its low tolerance-inducing capability may be correlated with its ability to bind both the MOR and DOR. Copyright © 2011 Elsevier Inc. All rights reserved.

  16. 75 FR 8921 - Grant of Authority for Subzone Status; Brightpoint North America L.P. (Cell Phone Kitting and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-26

    ... Status; Brightpoint North America L.P. (Cell Phone Kitting and Distribution) Indianapolis, IN Pursuant to... the cell phone kitting and distribution facilities of Brightpoint North America L.P., located in... cell phones at the facilities of Brightpoint North America L.P., located in Plainfield, Indiana...

  17. 75 FR 61219 - Aerospace Safety Advisory Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (10-116)] Aerospace Safety Advisory Panel... Aeronautics and Space Administration announces a forthcoming meeting of the Aerospace Safety Advisory Panel... Dakon, Aerospace Safety Advisory Panel Executive Director, National Aeronautics and Space Administration...

  18. 76 FR 19147 - Aerospace Safety Advisory Panel; Meeting.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-06

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-030)] Aerospace Safety Advisory Panel... Aeronautics and Space Administration announce a forthcoming meeting of the Aerospace Safety Advisory Panel.... Kathy Dakon, Aerospace Safety Advisory Panel Executive Director, National Aeronautics and Space...

  19. 78 FR 15976 - Aerospace Safety Advisory Panel; Meeting.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-13

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice: 13-023] Aerospace Safety Advisory Panel... Aeronautics and Space Administration announce a forthcoming meeting of the Aerospace Safety Advisory Panel... Space Administration, Washington, DC 20546, (202) 358-1857. SUPPLEMENTARY INFORMATION: The Aerospace...

  20. 78 FR 56941 - Aerospace Safety Advisory Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-16

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice: 13-114] Aerospace Safety Advisory Panel... Aeronautics and Space Administration announces a forthcoming meeting of the Aerospace Safety Advisory Panel.... Harmony Myers, Aerospace Safety Advisory Panel Executive Director, National Aeronautics and Space...

  1. 77 FR 58413 - Aerospace Safety Advisory Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 12-074] Aerospace Safety Advisory Panel... Aeronautics and Space Administration announces a forthcoming meeting of the Aerospace Safety Advisory Panel.... Harmony Myers, Aerospace Safety Advisory Panel Executive Director, National Aeronautics and Space...

  2. 77 FR 38090 - Aerospace Safety Advisory Panel; Meeting.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-26

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 12-044] Aerospace Safety Advisory Panel... Aeronautics and Space Administration announces a forthcoming meeting of the Aerospace Safety Advisory Panel.... Harmony Myers, Aerospace Safety Advisory Panel Executive Director, National Aeronautics and Space...

  3. Capital raising of aerospace companies: equities or debts?

    NASA Astrophysics Data System (ADS)

    Hui-Shan, L.; Taw-Onn, Y.; Wai-Mun, H.

    2016-10-01

    Aerospace products enhance national and economic activities, thus maintaining the sustainability of aerospace industry is crucial. One of the perspectives in ensuring sustainability of aerospace companies is expansion of firms by raising funds for research and development in order to provide a reasonable profitability to the firms. This study comprises a sample of 47 aerospace companies from 2009 to 2015 to analyze the impact of raising fund by equities or debts to the profitability of the firms. The result indicates that capital raising through equities is preferable than debts. Moreover, the study also identifies that the profit of aerospace industry is volatile and there is cyclical reduction of the net income in the first quarter of the year. The management needs to make wise decisions in raising fund to ensure a healthy growth of the aerospace company.

  4. LpMab-23-recognizing cancer-type podoplanin is a novel predictor for a poor prognosis of early stage tongue cancer.

    PubMed

    Miyazaki, Akihiro; Nakai, Hiromi; Sonoda, Tomoko; Hirohashi, Yoshihiko; Kaneko, Mika K; Kato, Yukinari; Sawa, Yoshihiko; Hiratsuka, Hiroyoshi

    2018-04-20

    We report that the reactivity of a novel monoclonal antibody LpMab-23 for human cancer-type podoplanin (PDPN) is a predictor for a poor prognosis of tongue cancer. The association between LpMab-23-recognizing cancer-type PDPN expression and clinical/pathological features were analyzed on 60 patients with stage I and II tongue cancer treated with transoral resection of the primary tumor. In the mode of invasion, the LpMab-23-dull/negative cases were significantly larger in cases with low-grade malignancies and without late cervical lymph node metastasis, than in cases with high-grade malignancies and the metastasis. In the high-grade malignant cases, LpMab-23-positive cases were significantly larger than LpMab-23-dull/negative cases. The Kaplan-Meier curves of the five-year metastasis-free survival rate (MFS) were significantly lower in the LpMab-23 positive patients than in LpMab-23 dull/negative patients. The LpMab-23-dull/negative cases showed the highest MFS in all of the clinical/pathological features and particularly, the MFS of the LpMab-23 positive cases decreased to less than 60% in the first year. In the Cox proportional hazard regression models a comparison of the numbers of LpMab-23 dull/negative with positive cases showed the highest hazard ratio with statistical significance in all of the clinical/pathological features. LpMab-23 positive cases may be considered to present a useful predictor of poor prognosis for early stage tongue cancer.

  5. ChLpMab-23: Cancer-Specific Human-Mouse Chimeric Anti-Podoplanin Antibody Exhibits Antitumor Activity via Antibody-Dependent Cellular Cytotoxicity.

    PubMed

    Kaneko, Mika K; Nakamura, Takuro; Kunita, Akiko; Fukayama, Masashi; Abe, Shinji; Nishioka, Yasuhiko; Yamada, Shinji; Yanaka, Miyuki; Saidoh, Noriko; Yoshida, Kanae; Fujii, Yuki; Ogasawara, Satoshi; Kato, Yukinari

    2017-06-01

    Podoplanin is expressed in many cancers, including oral cancers and brain tumors. The interaction between podoplanin and its receptor C-type lectin-like receptor 2 (CLEC-2) has been reported to be involved in cancer metastasis and tumor malignancy. We previously established many monoclonal antibodies (mAbs) against human podoplanin using the cancer-specific mAb (CasMab) technology. LpMab-23 (IgG 1 , kappa), one of the mouse anti-podoplanin mAbs, was shown to be a CasMab. However, we have not shown the usefulness of LpMab-23 for antibody therapy against podoplanin-expressing cancers. In this study, we first determined the minimum epitope of LpMab-23 and revealed that Gly54-Leu64 peptide, especially Gly54, Thr55, Ser56, Glu57, Asp58, Arg59, Tyr60, and Leu64 of podoplanin, is a critical epitope of LpMab-23. We further produced human-mouse chimeric LpMab-23 (chLpMab-23) and investigated whether chLpMab-23 exerts antibody-dependent cellular cytotoxicity (ADCC) and antitumor activity. In flow cytometry, chLpMab-23 showed high sensitivity against a podoplanin-expressing glioblastoma cell line, LN319, and an oral cancer cell line, HSC-2. chLpMab-23 also showed ADCC activity against podoplanin-expressing CHO cells (CHO/podoplanin). In xenograft models with HSC-2 and CHO/podoplanin, chLpMab-23 exerts antitumor activity using human natural killer cells, indicating that chLpMab-23 could be useful for antibody therapy against podoplanin-expressing cancers.

  6. 75 FR 64306 - Shell Energy North America (US), LP; Notice of Institution of Proceeding and Refund Effective Date

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-19

    ...] Shell Energy North America (US), LP; Notice of Institution of Proceeding and Refund Effective Date...), concerning the justness and reasonableness of Shell Energy North America (US), LP's market- based rate authority in the Central and Southwest balancing authority area. Shell Energy North America (US), LP, 133...

  7. The 1990 NASA Aerospace Battery Workshop

    NASA Technical Reports Server (NTRS)

    Kennedy, Lewis M. (Compiler)

    1991-01-01

    This document contains the proceedings of the 21st annual NASA Aerospace Battery Workshop, hosted by the Marshall Space Flight Center on December 4-6, 1990. The workshop was attended by scientists and engineers from various agencies of the U.S. Government, aerospace contractors, and battery manufacturers as well as participation in like kind from the European Space Agency member nations. The subjects covered included nickel-cadmium, nickel-hydrogen, silver-zinc, lithium based chemistries, and advanced technologies as they relate to high reliability operations in aerospace applications.

  8. Aerospace applications of magnetic bearings

    NASA Technical Reports Server (NTRS)

    Downer, James; Goldie, James; Gondhalekar, Vijay; Hockney, Richard

    1994-01-01

    Magnetic bearings have traditionally been considered for use in aerospace applications only where performance advantages have been the primary, if not only, consideration. Conventional wisdom has been that magnetic bearings have certain performance advantages which must be traded off against increased weight, volume, electric power consumption, and system complexity. These perceptions have hampered the use of magnetic bearings in many aerospace applications because weight, volume, and power are almost always primary considerations. This paper will review progress on several active aerospace magnetic bearings programs at SatCon Technology Corporation. The magnetic bearing programs at SatCon cover a broad spectrum of applications including: a magnetically-suspended spacecraft integrated power and attitude control system (IPACS), a magnetically-suspended momentum wheel, magnetic bearings for the gas generator rotor of a turboshaft engine, a vibration-attenuating magnetic bearing system for an airborne telescope, and magnetic bearings for the compressor of a space-rated heat pump system. The emphasis of these programs is to develop magnetic bearing technologies to the point where magnetic bearings can be truly useful, reliable, and well tested components for the aerospace community.

  9. Aerospace applications of magnetic bearings

    NASA Astrophysics Data System (ADS)

    Downer, James; Goldie, James; Gondhalekar, Vijay; Hockney, Richard

    1994-05-01

    Magnetic bearings have traditionally been considered for use in aerospace applications only where performance advantages have been the primary, if not only, consideration. Conventional wisdom has been that magnetic bearings have certain performance advantages which must be traded off against increased weight, volume, electric power consumption, and system complexity. These perceptions have hampered the use of magnetic bearings in many aerospace applications because weight, volume, and power are almost always primary considerations. This paper will review progress on several active aerospace magnetic bearings programs at SatCon Technology Corporation. The magnetic bearing programs at SatCon cover a broad spectrum of applications including: a magnetically-suspended spacecraft integrated power and attitude control system (IPACS), a magnetically-suspended momentum wheel, magnetic bearings for the gas generator rotor of a turboshaft engine, a vibration-attenuating magnetic bearing system for an airborne telescope, and magnetic bearings for the compressor of a space-rated heat pump system. The emphasis of these programs is to develop magnetic bearing technologies to the point where magnetic bearings can be truly useful, reliable, and well tested components for the aerospace community.

  10. 76 FR 49468 - Tesoro Refining and Marketing Company, SFPP, L.P.; Notice of Complaint

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-10

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. OR11-20-000] Tesoro Refining and Marketing Company, SFPP, L.P.; Notice of Complaint Take notice that on August 2, 2011, pursuant to... Marketing Company (Complainant) filed a complaint against SFPP, L.P. (SFPP or Respondent), challenging the...

  11. Accommodation of Nontraditional Aerospace Degree Aspirants

    ERIC Educational Resources Information Center

    Schukert, Michael A.

    1977-01-01

    Presents results of a national survey of institutions offering college level aerospace studies. Primary survey concern is the availability of nontraditional aerospace education programs; however, information pertaining to institution characteristics, program characteristics, and staffing are also included. (SL)

  12. Aerospace Engineering Systems

    NASA Technical Reports Server (NTRS)

    VanDalsem, William R.; Livingston, Mary E.; Melton, John E.; Torres, Francisco J.; Stremel, Paul M.

    1999-01-01

    Continuous improvement of aerospace product development processes is a driving requirement across much of the aerospace community. As up to 90% of the cost of an aerospace product is committed during the first 10% of the development cycle, there is a strong emphasis on capturing, creating, and communicating better information (both requirements and performance) early in the product development process. The community has responded by pursuing the development of computer-based systems designed to enhance the decision-making capabilities of product development individuals and teams. Recently, the historical foci on sharing the geometrical representation and on configuration management are being augmented: Physics-based analysis tools for filling the design space database; Distributed computational resources to reduce response time and cost; Web-based technologies to relieve machine-dependence; and Artificial intelligence technologies to accelerate processes and reduce process variability. Activities such as the Advanced Design Technologies Testbed (ADTT) project at NASA Ames Research Center study the strengths and weaknesses of the technologies supporting each of these trends, as well as the overall impact of the combination of these trends on a product development event. Lessons learned and recommendations for future activities will be reported.

  13. Autoregressive model in the Lp norm space for EEG analysis.

    PubMed

    Li, Peiyang; Wang, Xurui; Li, Fali; Zhang, Rui; Ma, Teng; Peng, Yueheng; Lei, Xu; Tian, Yin; Guo, Daqing; Liu, Tiejun; Yao, Dezhong; Xu, Peng

    2015-01-30

    The autoregressive (AR) model is widely used in electroencephalogram (EEG) analyses such as waveform fitting, spectrum estimation, and system identification. In real applications, EEGs are inevitably contaminated with unexpected outlier artifacts, and this must be overcome. However, most of the current AR models are based on the L2 norm structure, which exaggerates the outlier effect due to the square property of the L2 norm. In this paper, a novel AR object function is constructed in the Lp (p≤1) norm space with the aim to compress the outlier effects on EEG analysis, and a fast iteration procedure is developed to solve this new AR model. The quantitative evaluation using simulated EEGs with outliers proves that the proposed Lp (p≤1) AR can estimate the AR parameters more robustly than the Yule-Walker, Burg and LS methods, under various simulated outlier conditions. The actual application to the resting EEG recording with ocular artifacts also demonstrates that Lp (p≤1) AR can effectively address the outliers and recover a resting EEG power spectrum that is more consistent with its physiological basis. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. International Conference on Aerospace Trends...2001 - From Aeroplane to Aerospace Plane, Thiruvananthapuram, India, June 27, 28, 1991, Proceedings

    NASA Astrophysics Data System (ADS)

    1991-08-01

    Consideration is given to operational characteristics of future launch vehicles, trends in propulsion technology, technology challenges in the development of cryogenic propulsion systems for future reusable space-launch vehicles, estimation of the overall drag coefficient of an aerospace plane, and self-reliance in aerospace structures. Attention is also given to basic design concepts for smart actuators for aerospace plane control, a software package for the preliminary design of a helicopter, and multiconstraint wing optimization.

  15. The development of aerospace polyimide adhesives

    NASA Technical Reports Server (NTRS)

    St.clair, A. K.; St.clair, T. L.

    1983-01-01

    Few materials are available which can be used as aerospace adhesives at temperatures in the range of 300 C. The Materials Division at NASA-Langley Research Center developed several high temperature polyimide adhesives to fulfill the stringent needs of current aerospace programs. These adhesives are the result of a decade of basic research studies on the structure property relationships of both linear and addition aromatic polyimides. The development of both in house and commercially available polyimides is reviewed with regards to their potential for use as aerospace adhesives.

  16. Aerospace Technology.

    ERIC Educational Resources Information Center

    Paschke, Jean; And Others

    1991-01-01

    Describes the Sauk Rapids (Minnesota) High School aviation and aerospace curriculum that was developed by Curtis Olson and the space program developed by Gerald Mayall at Philadelphia's Northeast High School. Both were developed in conjunction with NASA. (JOW)

  17. Association of Lp-PLA2-A and early recurrence of vascular events after TIA and minor stroke.

    PubMed

    Lin, Jinxi; Zheng, Hongwei; Cucchiara, Brett L; Li, Jiejie; Zhao, Xingquan; Liang, Xianhong; Wang, Chunxue; Li, Hao; Mullen, Michael T; Johnston, S Claiborne; Wang, Yilong; Wang, Yongjun

    2015-11-03

    To determine the association of lipoprotein-associated phospholipase A2 (Lp-PLA2) measured in the acute period and the short-term risk of recurrent vascular events in patients with TIA or minor stroke. We measured Lp-PLA2 activity (Lp-PLA2-A) in a subset of 3,201 participants enrolled in the CHANCE (Clopidogrel in High-Risk Patients with Acute Non-disabling Cerebrovascular Events) trial. Participants with TIA or minor stroke were enrolled within 24 hours of symptom onset and randomized to single or dual antiplatelet therapy. In the current analysis, the primary outcome was defined as the composite of ischemic stroke, myocardial infarction, or death within 90 days. The composite endpoint occurred in 299 of 3,021 participants (9.9%). The population average Lp-PLA2-A level was 209 ± 59 nmol/min/mL (95% confidence interval [CI] 207-211). Older age, male sex, and current smoking were associated with higher Lp-PLA2-A levels. Lp-PLA2-A was significantly associated with the primary endpoint (adjusted hazard ratio 1.07, 95% CI 1.01-1.13 for every 30 nmol/min/mL increase). Similar results were seen for ischemic stroke alone. Adjustment for low-density lipoprotein cholesterol attenuated the association between Lp-PLA2-A and the primary endpoint (adjusted hazard ratio 1.04, 95% CI 0.97-1.11 for every 30 nmol/min/mL increase). Higher levels of Lp-PLA2-A in the acute period are associated with increased short-term risk of recurrent vascular events. © 2015 American Academy of Neurology.

  18. 75 FR 38802 - Copano Pipelines/Upper Gulf Coast, L.P.; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-43-000] Copano Pipelines/Upper Gulf Coast, L.P.; Notice of Baseline Filing June 28, 2010. Take notice that on June 24, 2010, Copano Pipelines/Upper Gulf Coast, L.P. submitted a baseline filing of its Statement of Operating...

  19. The 42nd Aerospace Mechanism Symposium

    NASA Technical Reports Server (NTRS)

    Boesiger, Edward A. (Editor); Hakun, Claef (Editor)

    2014-01-01

    The Aerospace Mechanisms Symposium (AMS) provides a unique forum for those active in the design, production, and use of aerospace mechanisms. A major focus is the reporting of problems and solutions associated with the development, and flight certification of new mechanisms.

  20. 77 FR 30589 - SteelRiver Infrastructure Partners LP, SteelRiver Infrastructure Associates LLC, SteelRiver...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-23

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35622] SteelRiver Infrastructure Partners LP, SteelRiver Infrastructure Associates LLC, SteelRiver Infrastructure Fund North America LP, and Patriot Funding LLC--Control Exemption--Patriot Rail Corp., et al. SteelRiver...

  1. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 6: Aerospace knowledge diffusion in the academic community: A report of phase 3 activities of the NASA/DOD Aerospace Knowledge Diffusion Research Project

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Kennedy, John M.

    1990-01-01

    Descriptive and analytical data regarding the flow of aerospace-based scientific and technical information (STI) in the academic community are presented. An overview is provided of the Federal Aerospace Knowledge Diffusion Research Project, illustrating a five-year program on aerospace knowledge diffusion. Preliminary results are presented of the project's research concerning the information-seeking habits, practices, and attitudes of U.S. aerospace engineering and science students and faculty. The type and amount of education and training in the use of information sources are examined. The use and importance ascribed to various information products by U.S. aerospace faculty and students including computer and other information technology is assessed. An evaluation of NASA technical reports is presented and it is concluded that NASA technical reports are rated high in terms of quality and comprehensiveness, citing Engineering Index and IAA as the most frequently used materials by faculty and students.

  2. Smell of danger: an analysis of LP-gas odorization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cain, W.S.; Turk, A.

    1985-03-01

    LP-gas derives warning properties from the odorants ethyl mercaptan or thiophane. Laboratory tests have implied that the average person has the ability to smell the odors before leaking LP-gas reaches one-fifth its lower limit of flammability. Generally, however, laboratory tests ignore or discard persons with a poor sense of smell, especially the elderly and persons with certain types of hyposmia. Some persons who apparently can smell the warning agents when directed may otherwise fail to notice or identify them. Elderly men seem particularly vulnerable to instances of incidental anosmia and olfactory agnosia. Psychophysical testing of the warning agents has beenmore » rather unsophisticated. There exists neither a standard protocol for testing nor adequate specification of the perceptual properties that might make one warning agent better than another. Without such developments, improvement in warning agents will fail to occur. Possible improvements include increases in concentration, the use of blends to insure more uniform delivery of agent and, to decrease the perceptual vulnerability of relatively insensitive people, use of agents with favorable psychophysical (stimulus-response) functions and use of agents with favorable adaptation characteristics. Even without a change in existing products, it seems advisable to learn more about the vulnerability of LP-gas users and to employ educational means to reduce risks.« less

  3. Advanced Ceramic Materials for Future Aerospace Applications

    NASA Technical Reports Server (NTRS)

    Misra, Ajay

    2015-01-01

    With growing trend toward higher temperature capabilities, lightweight, and multifunctionality, significant advances in ceramic matrix composites (CMCs) will be required for future aerospace applications. The presentation will provide an overview of material requirements for future aerospace missions, and the role of ceramics and CMCs in meeting those requirements. Aerospace applications will include gas turbine engines, aircraft structure, hypersonic and access to space vehicles, space power and propulsion, and space communication.

  4. Sealed aerospace metal-hydride batteries

    NASA Technical Reports Server (NTRS)

    Coates, Dwaine

    1992-01-01

    Nickel metal hydride and silver metal hydride batteries are being developed for aerospace applications. There is a growing market for smaller, lower cost satellites which require higher energy density power sources than aerospace nickel-cadmium at a lower cost than space nickel-hydrogen. These include small LEO satellites, tactical military satellites and satellite constellation programs such as Iridium and Brilliant Pebbles. Small satellites typically do not have the spacecraft volume or the budget required for nickel-hydrogen batteries. NiCd's do not have adequate energy density as well as other problems such as overcharge capability and memory effort. Metal hydride batteries provide the ideal solution for these applications. Metal hydride batteries offer a number of advantages over other aerospace battery systems.

  5. Aerospace Measurements: Challenges and Opportunities

    NASA Technical Reports Server (NTRS)

    Conway, Bruce A.

    1992-01-01

    New aerospace research initiatives offer both challenges and opportunities to rapidly-emerging electronics and electro-optics technology. Defining and implementing appropriate measurement technology development programs in response to the aeronautical ground facility research and testing needs of the new initiatives poses some particularly important problems. This paper discusses today's measurement challenges along with some of the technological opportunities which offer some hope for meeting the challenges, and describes measurement technology activities currently underway in the Langley Research Center's Instrument Research Division to address modern aerospace research and design engineering requirements. Projected and realized benefits and payoffs from the ongoing measurement and instrumentation efforts will be emphasized. A discussion of future trends in the aerospace measurement technology field will be included.

  6. Photogrammetric techniques for aerospace applications

    NASA Astrophysics Data System (ADS)

    Liu, Tianshu; Burner, Alpheus W.; Jones, Thomas W.; Barrows, Danny A.

    2012-10-01

    Photogrammetric techniques have been used for measuring the important physical quantities in both ground and flight testing including aeroelastic deformation, attitude, position, shape and dynamics of objects such as wind tunnel models, flight vehicles, rotating blades and large space structures. The distinct advantage of photogrammetric measurement is that it is a non-contact, global measurement technique. Although the general principles of photogrammetry are well known particularly in topographic and aerial survey, photogrammetric techniques require special adaptation for aerospace applications. This review provides a comprehensive and systematic summary of photogrammetric techniques for aerospace applications based on diverse sources. It is useful mainly for aerospace engineers who want to use photogrammetric techniques, but it also gives a general introduction for photogrammetrists and computer vision scientists to new applications.

  7. Acting Administrator Lightfoot Visits Ball Aerospace

    NASA Image and Video Library

    2017-04-06

    Acting NASA Administrator Robert Lightfoot, left, views a clean room with Tim Schoenweis, senior project engineer for the Ozone Mapping Profiler Suite (OMPS) at Ball Aerospace, right, Thursday, April 6, 2017 at Ball Aerospace in Boulder, Colo. Photo Credit: (NASA/Joel Kowsky)

  8. Acting Administrator Lightfoot Visits Ball Aerospace

    NASA Image and Video Library

    2017-04-06

    Acting NASA Deputy Administrator Lesa Roe, center, views a clean room with Tim Schoenweis, senior project engineer for the Ozone Mapping Profiler Suite (OMPS) at Ball Aerospace, left, Thursday, April 6, 2017 at Ball Aerospace in Boulder, Colo. Photo Credit: (NASA/Joel Kowsky)

  9. Novel Monoclonal Antibody LpMab-17 Developed by CasMab Technology Distinguishes Human Podoplanin from Monkey Podoplanin.

    PubMed

    Kato, Yukinari; Ogasawara, Satoshi; Oki, Hiroharu; Honma, Ryusuke; Takagi, Michiaki; Fujii, Yuki; Nakamura, Takuro; Saidoh, Noriko; Kanno, Hazuki; Umetsu, Mitsuo; Kamata, Satoshi; Kubo, Hiroshi; Yamada, Mitsuhiro; Sawa, Yoshihiko; Morita, Kei-Ichi; Harada, Hiroyuki; Suzuki, Hiroyoshi; Kaneko, Mika Kato

    2016-04-01

    Podoplanin (PDPN) is a type-I transmembrane sialoglycoprotein, which possesses a platelet aggregation-stimulating (PLAG) domain in its N-terminus. Among the three PLAG domains, O-glycan on Thr52 of PLAG3 is critical for the binding with C-type lectin-like receptor-2 (CLEC-2) and is essential for platelet-aggregating activity of PDPN. Although many anti-PDPN monoclonal antibodies (mAbs) have been established, almost all mAbs bind to PLAG domains. We recently established CasMab technology to produce mAbs against membranous proteins. Using CasMab technology, we produced a novel anti-PDPN mAb, LpMab-17, which binds to non-PLAG domains. LpMab-17 clearly detected endogenous PDPN of cancer cells and normal cells in Western-blot, flow cytometry, and immunohistochemistry. LpMab-17 recognized glycan-deficient PDPN in flow cytometry, indicating that the interaction between LpMab-17 and PDPN is independent of its glycosylation. The minimum epitope of LpMab-17 was identified as Gly77-Asp82 of PDPN using enzyme-linked immunosorbent assay. Of interest, LpMab-17 did not bind to monkey PDPN, whereas the homology is 94% between human PDPN and monkey PDPN, indicating that the epitope of LpMab-17 is unique compared with the other anti-PDPN mAbs. The combination of different epitope-possessing mAbs could be advantageous for the PDPN-targeting diagnosis or therapy.

  10. 75 FR 51451 - Erie Boulevard Hydropower, L.P.; Notice of Intent To File License Application, Filing of Pre...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... Hydropower, L.P.; Notice of Intent To File License Application, Filing of Pre-Application Document, and.... Project No.: 7320-040. c. Dated Filed: June 29, 2010. d. Submitted By: Erie Boulevard Hydropower, L.P. e...: John Mudre at (202) 502-8902; or e-mail at [email protected] . j. Erie Boulevard Hydropower, L.P...

  11. LP-search and its use in analysis of the accuracy of control systems with acoustical models

    NASA Technical Reports Server (NTRS)

    Sergeyev, V. I.; Sobol, I. M.; Statnikov, R. B.; Statnikov, I. N.

    1973-01-01

    The LP-search is proposed as an analog of the Monte Carlo method for finding values in nonlinear statistical systems. It is concluded that: To attain the required accuracy in solution to the problem of control for a statistical system in the LP-search, a considerably smaller number of tests is required than in the Monte Carlo method. The LP-search allows the possibility of multiple repetitions of tests under identical conditions and observability of the output variables of the system.

  12. Worldwide surplus of LP-gases to grow, expert tells European meet in Venice

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1988-07-01

    There appears to be a growing consensus among students of the LP-gas industry that (1) the worldwide surplus of supplies of LP-gases will continue and grow, and (2) this will provide ample opportunity for market development between now and the year 2000, but (3) that development will be largely in the field of petro-chemical feedstocks, although (4) if the price should not remain competitive with feedstocks such as naphtha, the surpluses could find their way into the U.S., if (5) the price is right. This viewpoint was set forth for the benefit of the delegates to the convention May 19-20more » of the European LP-Gas Association in Venice, Italy, by Rick Haun, vice president of Purvin and Gertz, the Dallas consulting firm.« less

  13. Aerospace engineers: We're tomorrow-minded people

    NASA Technical Reports Server (NTRS)

    Lewis, M. H.

    1981-01-01

    Brief job-related autobiographical sketches of engineers working on NASA aerospace projects are presented. Career and educational guidance is offered to students thinking about entering the aerospace field.

  14. The Need for an Aerospace Pharmacy Residency

    NASA Technical Reports Server (NTRS)

    Bayuse, T.; Schuyler, C.; Bayuse, Tina M.

    2007-01-01

    This viewgraph poster presentation reviews the rationale for a call for a new program in residency for aerospace pharmacy. Aerospace medicine provides a unique twist on traditional medicine, and a specialty has evolved to meet the training for physicians, and it is becoming important to develop such a program for training in pharmacy designed for aerospace. The reasons for this specialist training are outlined and the challenges of developing a program are reviewed.

  15. Hexavalent Chromium Reduction in the Aerospace Industry

    DTIC Science & Technology

    2010-12-01

    1 Hexavalent Chromium Reduction in the Aerospace Industry Unpublished work © 2010 Aerospace Industries Association of America, Inc. Lisa Goldberg...COVERED 00-00-2010 to 00-00-2010 4. TITLE AND SUBTITLE Hexavalent Chromium Reduction in the Aerospace Industry 5a. CONTRACT NUMBER 5b. GRANT...ABSTRACT AIA and its members have a long history in minimizing the use of hexavalent chromium in the manufacture of its products. Included in that history

  16. Supercomputing in Aerospace

    NASA Technical Reports Server (NTRS)

    Kutler, Paul; Yee, Helen

    1987-01-01

    Topics addressed include: numerical aerodynamic simulation; computational mechanics; supercomputers; aerospace propulsion systems; computational modeling in ballistics; turbulence modeling; computational chemistry; computational fluid dynamics; and computational astrophysics.

  17. 77 FR 34055 - Accreditation and Approval of Saybolt LP, as a Commercial Gauger and Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection Accreditation and Approval of Saybolt LP, as a Commercial Gauger and Laboratory AGENCY: U.S. Customs and Border Protection, Department of Homeland Security. ACTION: Notice of accreditation and approval of Saybolt LP, as a commercial...

  18. High Flight. Aerospace Activities, K-12.

    ERIC Educational Resources Information Center

    Oklahoma State Dept. of Education, Oklahoma City.

    Following discussions of Oklahoma aerospace history and the history of flight, interdisciplinary aerospace activities are presented. Each activity includes title, concept fostered, purpose, list of materials needed, and procedure(s). Topics include planets, the solar system, rockets, airplanes, air travel, space exploration, principles of flight,…

  19. Aerospace Technicians: We're Tomorrow-Minded People

    NASA Technical Reports Server (NTRS)

    Lewis, M. H.

    1981-01-01

    Brief job-related autobiographical sketches of technicians working on NASA aerospace projects are presented. Career and educational guidance is offered to students thinking about entering the field of aerospace technology.

  20. 76 FR 2432 - Bancshares Capital, L.P.; Notice of Surrender Under 13 CFR 107.1900

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-13

    ... SMALL BUSINESS ADMINISTRATION [License No. 10/10-0194] Bancshares Capital, L.P.; Notice of Surrender Under 13 CFR 107.1900 Pursuant to the authority granted to the United States Small Business... 107.1900 of the Small Business Administration Rules and Regulations Bancshares Capital, L.P., 16118...

  1. 77 FR 71585 - Brookfield Energy Marketing LP v. ISO New England Inc.; Notice of Complaint

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-03

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL13-23-000] Brookfield Energy Marketing LP v. ISO New England Inc.; Notice of Complaint Take notice that on November 21, 2012...), Brookfield Energy Marketing LP (Complainant) filed a formal complaint against ISO New England Inc...

  2. 76 FR 45247 - Tesoro Refining and Marketing Company v. SFPP, L.P.; Notice of Complaint

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-28

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. OR 11-18-000] Tesoro Refining and Marketing Company v. SFPP, L.P.; Notice of Complaint Take notice that on July 20, 2011... Marketing Company (Complainant) filed a formal complaint against SFPP L.P. (SFPP or Respondent) alleging...

  3. 75 FR 35017 - Brookfield Energy Marketing LP; Supplemental Notice That Initial Market-Based Rate Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-21

    ... Energy Marketing LP; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for... proceeding of Brookfield Energy Marketing LP's application for market-based rate authority, with an... protests and interventions in lieu of paper, using the FERC Online links at http://www.ferc.gov . To...

  4. Validation of ozone profile retrievals derived from the OMPS LP version 2.5 algorithm against correlative satellite measurements

    NASA Astrophysics Data System (ADS)

    Kramarova, Natalya A.; Bhartia, Pawan K.; Jaross, Glen; Moy, Leslie; Xu, Philippe; Chen, Zhong; DeLand, Matthew; Froidevaux, Lucien; Livesey, Nathaniel; Degenstein, Douglas; Bourassa, Adam; Walker, Kaley A.; Sheese, Patrick

    2018-05-01

    The Limb Profiler (LP) is a part of the Ozone Mapping and Profiler Suite launched on board of the Suomi NPP satellite in October 2011. The LP measures solar radiation scattered from the atmospheric limb in ultraviolet and visible spectral ranges between the surface and 80 km. These measurements of scattered solar radiances allow for the retrieval of ozone profiles from cloud tops up to 55 km. The LP started operational observations in April 2012. In this study we evaluate more than 5.5 years of ozone profile measurements from the OMPS LP processed with the new NASA GSFC version 2.5 retrieval algorithm. We provide a brief description of the key changes that had been implemented in this new algorithm, including a pointing correction, new cloud height detection, explicit aerosol correction and a reduction of the number of wavelengths used in the retrievals. The OMPS LP ozone retrievals have been compared with independent satellite profile measurements obtained from the Aura Microwave Limb Sounder (MLS), Atmospheric Chemistry Experiment Fourier Transform Spectrometer (ACE-FTS) and Odin Optical Spectrograph and InfraRed Imaging System (OSIRIS). We document observed biases and seasonal differences and evaluate the stability of the version 2.5 ozone record over 5.5 years. Our analysis indicates that the mean differences between LP and correlative measurements are well within required ±10 % between 18 and 42 km. In the upper stratosphere and lower mesosphere (> 43 km) LP tends to have a negative bias. We find larger biases in the lower stratosphere and upper troposphere, but LP ozone retrievals have significantly improved in version 2.5 compared to version 2 due to the implemented aerosol correction. In the northern high latitudes we observe larger biases between 20 and 32 km due to the remaining thermal sensitivity issue. Our analysis shows that LP ozone retrievals agree well with the correlative satellite observations in characterizing vertical, spatial and temporal

  5. Modulation of gut barrier function in patients with obstructive jaundice using probiotic LP299v.

    PubMed

    Jones, Claire; Badger, Stephen A; Regan, Mark; Clements, Barry W; Diamond, Tom; Parks, Rowan W; Taylor, Mark A

    2013-12-01

    This study aimed to determine the effect of LP229v on intestinal permeability and tumour necrosis factor (TNF) p55 receptor concentrations in patients with obstructive jaundice undergoing biliary drainage. Patients undergoing biliary drainage were recruited and randomized into three groups to receive Lactobacillus plantarum 299v (LP299v), inactivated LP299v (placebo) or water. These were administered daily at noon until 7 days after biliary drainage. Intestinal permeability was measured using the lactulose/mannitol (L/M) dual sugar absorption test on admission, the day before biliary drainage and on days 1 and 7 after biliary drainage. Blood and urine were collected to determine the L/M ratio and the TNF p55 receptor levels at each time point. A total of 25 patients were recruited; 12 had choledocholithiasis and nine had a periampullary tumour. Open surgical biliary drainage was performed in nine patients, endoscopic retrograde cholangiopancreatography in 12 and percutaneous transhepatic cholangiography in two. Five patients received LP299v, five received placebo and seven, water. The median L/M ratio was 0.035 (0.018-0.065) at baseline. No difference existed between the groups on admission, before drainage and on day 7 after drainage (P=0.59, 0.175 and 0.61, respectively). The L/M ratio was lower in the LP299v group on day 1 after drainage [0.01 (0.01) vs. 0.18 (0.03-0.3) and 0.11 (0.07-0.14); P=0.37]. Although the TNF p55 receptor levels were lower on day 1 after drainage in the LP299v group (15.3 vs. 30.9 vs. 82.7 ng/ml; P=0.43), the concentration at the four time points was similar (P=0.24, 0.96, 0.43 and 0.68). Pretreatment with probiotic LP299v improves intestinal permeability after biliary drainage and attenuates the inflammatory response. However, a larger multicentre trial is required to determine the effect on clinical outcome.

  6. NASA-UVa light aerospace alloy and structures technology program

    NASA Technical Reports Server (NTRS)

    Gangloff, Richard P.; Haviland, John K.; Herakovich, Carl T.; Pilkey, Walter D.; Pindera, Marek-Jerzy; Scully, John R.; Stoner, Glenn E.; Swanson, Robert E.; Thornton, Earl A.; Wawner, Franklin E., Jr.

    1991-01-01

    The general objective of the NASA-UVa Light Aerospace Alloy and Structures Technology Program was to conduct research on the performance of next generation, light weight aerospace alloys, composites, and associated thermal gradient structures. The following research areas were actively investigated: (1) mechanical and environmental degradation mechanisms in advanced light metals and composites; (2) aerospace materials science; (3) mechanics of materials and composites for aerospace structures; and (4) thermal gradient structures.

  7. The 26th Aerospace Mechanisms Symposium

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The proceedings of the 26th Aerospace Mechanisms Symposium, which was held at the Goddard Space Flight Center on May 13, 14, and 15, 1992 are reported. Technological areas covered include actuators, aerospace mechanism applications for ground support equipment, lubricants, latches, connectors and other mechanisms for large space structures.

  8. Sparse Adaptive Iteratively-Weighted Thresholding Algorithm (SAITA) for Lp-Regularization Using the Multiple Sub-Dictionary Representation

    PubMed Central

    Zhang, Jie; Fan, Shangang; Xiong, Jian; Cheng, Xiefeng; Sari, Hikmet; Adachi, Fumiyuki

    2017-01-01

    Both L1/2 and L2/3 are two typical non-convex regularizations of Lp (0Lp thresholding algorithm and then proposes a sparse adaptive iterative-weighted Lp thresholding algorithm (SAITA). Moreover, a simple yet effective regularization parameter is proposed to weight each sub-dictionary-based Lp regularizer. Simulation results have shown that the proposed SAITA not only performs better than the corresponding L1 algorithms but can also obtain a better recovery performance and achieve faster convergence than the conventional single-dictionary sparse transform-based Lp case. Moreover, we conduct some applications about sparse image recovery and obtain good results by comparison with relative work. PMID:29244777

  9. NASA Aerospace Flight Battery Program: Recommendations for Technical Requirements for Inclusion in Aerospace Battery Procurements. Volume 1, Part 2

    NASA Technical Reports Server (NTRS)

    Jung, David S.; Manzo, Michelle A.

    2010-01-01

    This NASA Aerospace Flight Battery Systems Working Group was chartered within the NASA Engineering and Safety Center (NESC). The Battery Working Group was tasked to complete tasks and to propose proactive work to address battery related, agency-wide issues on an annual basis. In its first year of operation, this proactive program addressed various aspects of the validation and verification of aerospace battery systems for NASA missions. Studies were performed, issues were discussed and in many cases, test programs were executed to generate recommendations and guidelines to reduce risk associated with various aspects of implementing battery technology in the aerospace industry. This document contains Part 2 - Volume I: Recommendations for Technical Requirements for Inclusion in Aerospace Battery Procurements of the program's operations.

  10. 75 FR 19646 - Cheniere Creole Trail Pipeline, L.P.; Notice of Request Under Blanket Authorization

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ... Creole Trail Pipeline, L.P.; Notice of Request Under Blanket Authorization April 7, 2010. Take notice that on April 2, 2010, Cheniere Creole Trail Pipeline, L.P. (Creole Trail), 700 Milam, Suite 800... Trail seeks authorization to construct and operate approximately 550 feet of 12-inch diameter pipe (no...

  11. 76 FR 45246 - Tesoro Refining and Marketing Company v. SFPP, L.P.; Notice of Complaint

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-28

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. OR11-19-000] Tesoro Refining and Marketing Company v. SFPP, L.P.; Notice of Complaint Take notice that on July 20, 2011, pursuant...), Tesoro Refining and Marketing Company (Tesoro) filed a formal complaint against SFPP, L.P. (SFPP). Tesoro...

  12. The 27th Aerospace Mechanisms Symposium

    NASA Technical Reports Server (NTRS)

    Mancini, Ron (Compiler)

    1993-01-01

    The proceedings of the 27th Aerospace Mechanisms Symposium, which was held at ARC, Moffett Field, California, on 12-14 May 1993, are reported. Technological areas covered include the following: actuators, aerospace mechanism applications for ground support equipment, lubricants, latches, connectors, robotic mechanisms, and other mechanisms for large space structures.

  13. 77 FR 74579 - Airworthiness Directives; Gulfstream Aerospace Corporation Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-17

    ... Airworthiness Directives; Gulfstream Aerospace Corporation Airplanes AGENCY: Federal Aviation Administration... directive (AD) for certain Gulfstream Aerospace Corporation Model GIV-X airplanes. This AD requires... Aerospace Corporation, Technical Publications Dept., P.O. Box 2206, Savannah, GA 31402-2206; telephone 800...

  14. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 10: The NASA/DOD Aerospace Knowledge Diffusion Research Project

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Kennedy, John M.; Barclay, Rebecca O.

    1991-01-01

    The role of the NASA/DOD Aerospace Knowledge DIffusion Research Project in helping to maintain U.S. competitiveness is addressed. The phases of the project are examined in terms of the focus, emphasis, subjects, methods, and desired outcomes. The importance of the project to aerospace R&D is emphasized.

  15. 76 FR 76802 - Riverside Micro-Cap Fund II, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-08

    ... SMALL BUSINESS ADMINISTRATION [License No. 02/02-0646] Riverside Micro-Cap Fund II, L.P.; Notice... hereby given that Riverside Micro-Cap Fund II, L.P., 45 Rockefeller Center, New York, NY 10111, a Federal... Regulations (13 CFR 107.730). Riverside Micro-Cap Fund II, L.P. proposes to provide equity security financing...

  16. 77 FR 7655 - Riverside Micro-Cap Fund II, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-13

    ... SMALL BUSINESS ADMINISTRATION [License No. 02/02-0646] Riverside Micro-Cap Fund II, L.P.; Notice... hereby given that Riverside Micro-Cap Fund II, L.P., 45 Rockefeller Center, New York, NY 10111, a Federal... Regulations (13 CFR 107.730). Riverside Micro-Cap Fund II, L.P. proposes to provide equity security financing...

  17. Increased risk of coronary artery calcification progression in subjects with high baseline Lp(a) levels: The Kangbuk Samsung Health Study.

    PubMed

    Cho, Jung Hwan; Lee, Da Young; Lee, Eun Seo; Kim, Jihyun; Park, Se Eun; Park, Cheol-Young; Lee, Won-Young; Oh, Ki-Won; Park, Sung-Woo; Rhee, Eun-Jung

    2016-11-01

    Results from previous studies support the association of lipoprotein(a) [Lp(a)] levels and coronary artery disease risk. In this study, we analyzed the association between baseline Lp(a) levels and future progression of coronary artery calcification (CAC) in apparently healthy Korean adults. A total of 2611 participants (mean age: 41years, 92% mend) who underwent a routine health check-up in 2010 and 2014 were enrolled. Coronary artery calcium score (CACS) were measured by multi-detector computed tomography. Baseline Lp(a) was measured by high-sensitivity immunoturbidimetric assay. Progression of CAC was defined as a change in CACS >0 over four years. Bivariate correlation analyses with baseline Lp(a) and other metabolic parameters revealed age, total cholesterol, HDL-C, LDL-C and CACS to have a significant positive correlation, while body weight, fasting glucose level, blood pressure and triglyceride level were negatively correlated with baseline Lp(a) level. After four years of follow-up, 635 subjects (24.3%) had CAC progression. The participants who had CAC progression were older, composed of more men, more obese, and had higher fasting glucose levels and worse baseline lipid profiles compared to those who did not have CAC progression. The mean serum Lp(a) level was significantly higher in subjects who had CAC progression compared to those who did not (32.5 vs. 28.9mg/dL, p<0.01). When the risk for CAC progression according to baseline Lp(a) was calculated, those with Lp(a) level≥50mg/dL had an odds ratio of 1.333 (95% CI 1.027-1.730) for CAC progression compared to those with Lp(a)<50mg/dL after adjusting for confounding factors. In this study, the subjects who had higher Lp(a) were at significantly higher risk for CAC progression after four years of follow-up, suggesting the role of high Lp(a) in CAC progression. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  18. 75 FR 26224 - Cheniere Creole Trail Pipeline, L.P.; Notice of Request Under Blanket Authorization

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... Creole Trail Pipeline, L.P.; Notice of Request Under Blanket Authorization May 4, 2010. Take notice that on April 29, 2010, Cheniere Creole Trail Pipeline, L.P. (Creole Trail), 700 Milam, Suite 800, Houston... 157.216(b) of the Commission's regulations under the Natural Gas Act (NGA). Creole Trail seeks...

  19. NASA/DoD aerospace knowledge diffusion research project. VIII - The role of the information intermediary in the diffusion of aerospace knowledge

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Kennedy, John M.; Barclay, Rebecca O.

    1990-01-01

    The U.S. aerospace industry is experiencing profound changes created by a combination of domestic actions and circumstances such as airline deregulation. Other changes result from external trends such as emerging foreign competition. These circumstances intensify the need to understand the production, transfer, and utilization of knowledge as a precursor to the rapid diffusion of technology. This article presents a conceptual framework for understanding the diffusion of aerospace knowledge. The framework focuses on the information channels and members of the social system associated with the aerospace knowledge diffusion process, placing particular emphasis on aerospace librarians as information intermediaries.

  20. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 26: The relationship between technology policy and scientific and technical information within the US and Japanese aerospace industries

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.

    1993-01-01

    Government technology policy has nurtured the growth of the aerospace industry which is vital to both the U.S. and Japanese economies. Japanese technology policy differs significantly from U.S. technology policy, however, particularly with respect to the production, transfer, and use of scientific and technical information (STI). In this paper, we discuss the unique position of the aerospace industry in the U.S. and Japan, U.S. and Japanese aerospace policy, and the role of STI in the process of aerospace innovation. The information-seeking behaviors of U.S. and Japanese aerospace engineers and scientists are compared. The authors advocate the development of innovation-adoption technology and STI policy goals for U.S. aerospace and the inclusion of an aerospace knowledge diffusion transfer system with an 'active' component for scanning and acquiring foreign aerospace technology and STI.

  1. Applications of aerospace technology in biology and medicine

    NASA Technical Reports Server (NTRS)

    Beall, H. C.; Beadles, R. L.; Brown, J. N., Jr.; Clingman, W. H.; Courtney, M. W.; Rouse, D. J.; Scearce, R. W.

    1979-01-01

    Medical products utilizing and incorporating aerospace technology were studied. A bipolar donor-recipient model for medical transfer is presented. The model is designed to: (1) identify medical problems and aerospace technology which constitute opportunities for successful medical products; (2) obtain early participation of industry in the transfer process; and (3) obtain acceptance by medical community of new medical products based on aerospace technology.

  2. Sunoco Pipeline, L.P. Clean Water Act Settlement - 2017

    EPA Pesticide Factsheets

    EPA, and the U.S. Department of Justice announced that Sunoco Pipeline, L.P. (Sunoco) has agreed to pay a civil penalty for alleged violation of the Clean Water Act stemming from a 2012 gasoline discharge near Wellington, Ohio.

  3. Poly-(R)-3-hydroxybutyrates (PHB) are Atherogenic Components of Lipoprotein Lp(a).

    PubMed

    Reusch, Rosetta N

    2015-12-01

    The hypothesis is that poly-(R)-3-hydroxybutyrates (PHB), linear polymers of the ketone body, R-3-hydroxybutyrate (R-3HB), are atherogenic components of lipoprotein Lp(a). PHB are universal constituents of biological cells and are thus components of all foods. Medium chain-length PHB (<200 residues) (mPHB) are located in membranes and organelles, and short-chain PHB (<15 residues) are covalently attached to certain proteins (cPHB). PHB are highly insoluble in water, but soluble in lipids in which they exhibit a high intrinsic viscosity. They have a higher density than other cellular lipids and they are very adhesive, i.e. they engage in multiple noncovalent interactions with other molecules and salts via hydrogen, hydrophobic and coordinate bonds, thus producing insoluble deposits. Following digestive processes, PHB enter the circulation in chylomicrons and very low density lipoproteins (VLDL). The majority of the PHB (>70%) are absorbed by albumin, which transports them to the liver for disposal. When the amount of PHB in the diet exceed the capacity of albumin to safely remove them from the circulation, the excess PHB remain in the lipid core of LDL particles that become constituents of lipoprotein Lp(a), and contribute to the formation of arterial deposits. In summary, the presence of PHB – water-insoluble, dense, viscous, adhesive polymers – in the lipid cores of the LDL moieties of Lp(a) particles supports the hypothesis that PHB are atherogenic components of Lp(a).

  4. 75 FR 39911 - Aerospace Supplier Development Mission to China

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-13

    ... DEPARTMENT OF COMMERCE International Trade Administration Aerospace Supplier Development Mission... Commercial Service (CS) is organizing an Aerospace Supplier Development Mission to China from November 7-17, 2010. The 2010 Aerospace Supplier Development Mission to China is being developed due to a successful...

  5. 78 FR 49908 - Airworthiness Directives; Eclipse Aerospace, Inc. Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-16

    ... Airworthiness Directives; Eclipse Aerospace, Inc. Airplanes AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new airworthiness directive (AD) for all Eclipse Aerospace... Eclipse Aerospace, Inc., 26 East Palatine Road, Wheeling, Illinois 60090; telephone: (877) 373-7978...

  6. Women, Innovation and Aerospace Event

    NASA Image and Video Library

    2012-03-08

    NASA Deputy Administrator, Lori Garver, gives the keynote address at the Women, Innovation and Aerospace event celebrating Women's History Month at the George Washington University Jack Morton Auditorium, Thursday, March 8, 2012 in Washington. The WIA day-long event will help to foster a discussion for students and early career professionals about how to continue to encourage women to enter and succeed in the field of aerospace. Photo Credit: (NASA/Carla Cioffi)

  7. Women, Innovation and Aerospace Event

    NASA Image and Video Library

    2012-03-08

    NASA Deputy Administrator, Lori Garver, far right, gives the keynote address at the Women, Innovation and Aerospace event celebrating Women's History Month at the George Washington University Jack Morton Auditorium, Thursday, March 8, 2012 in Washington. The WIA day-long event will help to foster a discussion for students and early career professionals about how to continue to encourage women to enter and succeed in the field of aerospace. Photo Credit: (NASA/Carla Cioffi)

  8. Women, Innovation and Aerospace Event

    NASA Image and Video Library

    2012-03-08

    Marcia Smith, President, spacepolicyonline.com, participates in a panel discussion at the Women, Innovation and Aerospace event celebrating Women's History Month at the George Washington University Jack Morton Auditorium, Thursday, March 8, 2012 in Washington. The WIA day-long event will help to foster a discussion for students and early career professionals about how to continue to encourage women to enter and succeed in the field of aerospace. Photo Credit: (NASA/Carla Cioffi)

  9. Polyimides: Thermally stable aerospace polymers

    NASA Technical Reports Server (NTRS)

    St.clair, A. K.

    1980-01-01

    An up to date review of available commercial and experimental high temperature polyimide resins which show potential for aerospace applications is presented. Current government research trends involving the use of polyimides as matrix resins for structural composites are discussed. Both the development of polyimides as adhesives for bonding metals and composites, and as films and coatings for use in an aerospace environment are reviewed. In addition, future trends for polyimides are proposed.

  10. Discovery of radio emission from the brown dwarf LP944-20.

    PubMed

    Berger, E; Ball, S; Becker, K M; Clarke, M; Frail, D A; Fukuda, T A; Hoffman, I M; Mellon, R; Momjian, E; Murphy, N W; Teng, S H; Woodruff, T; Zauderer, B A; Zavala, R T

    2001-03-15

    Brown dwarfs are not massive enough to sustain thermonuclear fusion of hydrogen at their centres, but are distinguished from gas-giant planets by their ability to burn deuterium. Brown dwarfs older than approximately 10 Myr are expected to possess short-lived magnetic fields and to emit radio and X-rays only very weakly from their coronae. An X-ray flare was recently detected on the brown dwarf LP944-20, whereas previous searches for optical activity (and one X-ray search) yielded negative results. Here we report the discovery of quiescent and flaring radio emission from LP944-20, with luminosities several orders of magnitude larger than predicted by the empirical relation between the X-ray and radio luminosities that has been found for many types of stars. Interpreting the radio data within the context of synchrotron emission, we show that LP944-20 has an unusually weak magnetic field in comparison to active M-dwarf stars, which might explain the previous null optical and X-ray results, as well as the strength of the radio emissions compared to those at X-ray wavelengths.

  11. US EPA Testing of LP & MP UV Disinfection Technologies

    EPA Science Inventory

    Presentation will discuss the ongoing USEPA research on UV disinfection addressing the following objectives: Conservatively predict log inactivation and RED of adenovirus with surrogates; Conduct many (LP=61) UV reactor conditions challenged with Ad2, B. pumilus, and MS2 & conduc...

  12. 77 FR 28375 - Eagle Rock Desoto Pipeline, L.P.; Notice of Petition for Rate Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR12-25-000] Eagle Rock Desoto Pipeline, L.P.; Notice of Petition for Rate Approval Take notice that on May 1, 2012, Eagle Rock Desoto Pipeline, L.P. (Desoto) filed a Rate Election pursuant to 284.123(b)(1) of the Commissions...

  13. iSTEM: The Aerospace Engineering Challenge

    ERIC Educational Resources Information Center

    English, Lyn D.; King, Donna T.; Hudson, Peter; Dawes, Les

    2014-01-01

    The authors developed The Paper Plane Challenge as one of a three-part response to The Aerospace Engineering Challenge. The Aerospace Engineering Challenge was the second of three multi-part activities that they had developed with the teachers during the year. Their aim was to introduce students to the exciting world of engineering, where they…

  14. 76 FR 1600 - U.S. Aerospace Supplier & Investment Mission

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ... DEPARTMENT OF COMMERCE International Trade Administration U.S. Aerospace Supplier & Investment... Commercial Service is organizing a U.S. Aerospace Supplier & Investment Mission to Montreal, Canada on May 2... parties interested in participating in the U.S. Aerospace Trade and Investment Mission must complete and...

  15. 78 FR 30243 - Airworthiness Directives; Eclipse Aerospace, Inc. Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-22

    ... Airworthiness Directives; Eclipse Aerospace, Inc. Airplanes AGENCY: Federal Aviation Administration (FAA), DOT... (AD) for all Eclipse Aerospace, Inc. Model EA500 airplanes equipped with Avio, Avio with ETT, or Avio... identified in this proposed AD, contact Eclipse Aerospace, Inc. 26 East Palatine Road, Wheeling, Illinois...

  16. Switchable narrow linewidth fiber laser with LP11 transverse mode output

    NASA Astrophysics Data System (ADS)

    Shen, Ya; Ren, Guobin; Yang, Yuguang; Yao, Shuzhi; Wu, Yue; Jiang, Youchao; Xu, Yao; Jin, Wenxing; Zhu, Bofeng; Jian, Shuisheng

    2018-01-01

    We experimentally demonstrate a switchable narrow linewidth single-longitudinal-mode (SLM) erbium-doped fiber (EDF) ring laser with LP11 transverse mode output. The laser is based on a mode selective all-fiber fused coupler which is composed of a single-mode fiber (SMF) and a two-mode fiber (TMF). By controlling the polarization state of the output light, the laser can provide narrow linewidth SLM output with LP11 transverse mode at two specific wavelengths, which correspond to two transmission peaks of the chirped moiré fiber grating (CMFBG). The 20 dB linewidth of the fiber laser for each wavelength is approximately 7.2 and 6.4 kHz.

  17. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 28: The technical communication practices of Russian and US aerospace engineers and scientists

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Keene, Michael L.; Flammia, Madelyn; Kennedy, John M.

    1993-01-01

    As part of Phase 4 of the NASA/DoD Aerospace Knowledge Diffusion Research Project, two studies were conducted that investigated the technical communication practices of Russian and U.S. aerospace engineers and scientists. Both studies had the same five objectives: first, to solicit the opinions of aerospace engineers and scientists regarding the importance of technical communication to their professions; second, to determine the use and production of technical communication by aerospace engineers and scientists; third, to seek their views about the appropriate content of the undergraduate course in technical communication; fourth, to determine aerospace engineers' and scientists' use of libraries, technical information centers, and on-line databases; and fifth, to determine the use and importance of computer and information technology to them. A self administered questionnaire was distributed to Russian aerospace engineers and scientists at the Central Aero-Hydrodynamic Institute (TsAGI) and to their U.S. counterparts at the NASA Ames Research Center and the NASA Langley Research Center. The completion rates for the Russian and U.S. surveys were 64 and 61 percent, respectively. Responses of the Russian and U.S. participants to selected questions are presented in this paper.

  18. Anti-soluble liver antigen/liver-pancreas (SLA/LP) antibodies in pediatric patients with autoimmune hepatitis.

    PubMed

    Vitozzi, Susana; Djilali-Saiah, Idriss; Lapierre, Pascal; Alvarez, Fernando

    2002-12-01

    Antibodies against soluble liver antigen/liver-pancreas (SLA/LP) have been associated with severe autoimmune hepatitis (AIH) and poor outcome, but most of these reports have focused on adult patients. The aim of this study was to assess the prevalence and clinical significance of anti-SLA/LP antibodies in a pediatric population with AIH. We developed a quantitative enzyme-linked immunoassay (ELISA), a Western blot (WB) and an immunoprecipitation assay (IPA) based on recombinant cDNA from activated Jurkat cells. The specificity of these tests was validated by testing 200 serum samples from healthy subjects, and from patients with liver and non-liver diseases. Anti-SLA/LP antibodies were found in patients with type 1 and type 2 AIH. The prevalence of these antibodies in patients with type 1 AIH was: 42% when tested by ELISA, 15% by WB and 50% by IPA. In patients with type 2 AIH, the prevalence rates were 42% by ELISA, 18% by WB and 44% by IPA. The mean titer values for anti-SLA/LP antibodies was significantly higher in type 2 AIH (1:1,300 +/- 339) than in type 1 AIH (1:600 +/- 71; p < 0.0001) and closely associated with higher titers of anti-liver kidney microsome type 1 (LKM1) and anti-liver cytosol type 1 (LC1) antibodies in sera. The presence of anti-SLA/LP showed a significant female preponderance in type 1 and 2 AIH patients (p = 0.0003 and p = 0.003, respectively), and was significantly correlated with a lower age at diagnosis (p = 0.05) in type 1 AIH patients. In conclusion, anti-SLA/LP antibodies in pediatric patients are associated with both type 1 and 2 AIH.

  19. 76 FR 55614 - Airworthiness Directives; Pacific Aerospace Limited Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-08

    ...-0971; Directorate Identifier 2011-CE-030-AD] RIN 2120-AA64 Airworthiness Directives; Pacific Aerospace... (AD) for Pacific Aerospace Limited Models FU24-954 and FU24A-954 airplanes modified with an unapproved... INFORMATION CONTACT: Karl Schletzbaum, Aerospace Engineer, FAA, Small Airplane Directorate, 901 Locust, Room...

  20. The importance of age and statin therapy in the interpretation of Lp-PLA(2) in ACS patients, and relation to CRP.

    PubMed

    Franeková, J; Kettner, J; Kubíček, Z; Jabor, A

    2015-01-01

    C-reactive protein (CRP) is a marker of arterial inflammation while lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is related to plaque instability. The aim of this study was to evaluate the correlation between the risk of unstable plaque presenting as acute coronary syndrome (ACS) and Lp-PLA(2), and to assess the influence of statins on interpretation of Lp-PLA(2). A total of 362 consecutive patients presenting to the emergency department (ED) with acute chest pain suggestive of ACS were evaluated by cardiologists as STEMI, NSTEMI, or unstable angina, and non-ACS. Serum biomarkers measured on admission: troponin I, C-reactive protein (Abbott), and Lp-PLA(2) (DiaDexus). Four groups were defined according to the final diagnosis and history of statin medication: ACS/statin-; ACS/statin+; non-ACS/statin-; non-ACS/statin+. Lp-PLA(2) was highest in ACS/statin- group; statins decreased Lp-PLA(2) both in ACS and non-ACS of about 20 %. Lp-PLA(2) was higher in ACS patients in comparison with non-ACS patients group without respect to statin therapy (p<0.001). Lp-PLA(2) predicted worse outcome (in terms of acute coronary syndrome) effectively in patients up to 62 years; limited prediction was found in older patients. C-reactive protein (CRP) failed to discriminate four groups of patients. Statin therapy and age should be taken into consideration while interpreting Lp-PLA(2) concentrations and lower cut-off values should be used for statin-treated persons.

  1. 78 FR 48205 - Ranger Alternative Management, L.P. and Ranger Funds Investment Trust; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-07

    ... Alternative Management, L.P. and Ranger Funds Investment Trust; Notice of Application August 1, 2013. AGENCY... Management, L.P. (``Ranger'') and Ranger Funds Investment Trust (the ``Trust''). Summary of Application... (e) certain registered management investment companies and unit investment trusts outside of the same...

  2. 76 FR 66710 - Erie Boulevard Hydropower, L.P.; Notice of Application Accepted for Filing, Soliciting Comments...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-27

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 5984-063] Erie Boulevard Hydropower, L.P.; Notice of Application Accepted for Filing, Soliciting Comments, Motions To Intervene, and....: 5984-063. c. Date Filed: May 10, 2011. d. Applicant: Erie Boulevard Hydropower, L.P. (dba Brookfield...

  3. NASA HPCC Technology for Aerospace Analysis and Design

    NASA Technical Reports Server (NTRS)

    Schulbach, Catherine H.

    1999-01-01

    The Computational Aerosciences (CAS) Project is part of NASA's High Performance Computing and Communications Program. Its primary goal is to accelerate the availability of high-performance computing technology to the US aerospace community-thus providing the US aerospace community with key tools necessary to reduce design cycle times and increase fidelity in order to improve safety, efficiency and capability of future aerospace vehicles. A complementary goal is to hasten the emergence of a viable commercial market within the aerospace community for the advantage of the domestic computer hardware and software industry. The CAS Project selects representative aerospace problems (especially design) and uses them to focus efforts on advancing aerospace algorithms and applications, systems software, and computing machinery to demonstrate vast improvements in system performance and capability over the life of the program. Recent demonstrations have served to assess the benefits of possible performance improvements while reducing the risk of adopting high-performance computing technology. This talk will discuss past accomplishments in providing technology to the aerospace community, present efforts, and future goals. For example, the times to do full combustor and compressor simulations (of aircraft engines) have been reduced by factors of 320:1 and 400:1 respectively. While this has enabled new capabilities in engine simulation, the goal of an overnight, dynamic, multi-disciplinary, 3-dimensional simulation of an aircraft engine is still years away and will require new generations of high-end technology.

  4. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 8: The role of the information intermediary in the diffusion of aerospace knowledge

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Kennedy, John M.; Barclay, Rebecca O.

    1990-01-01

    The United States aerospace industry is experiencing profound changes created by a combination of domestic actions and circumstances such as airline deregulation. Other changes result from external trends such as emerging foreign competition. These circumstances intensify the need to understand the production, transfer, and utilization of knowledge as a precursor to the rapid diffusion of technology. Presented here is a conceptual framework for understanding the diffusion of technology. A conceptual framework is given for understanding the diffusion of aerospace knowledge. The framework focuses on the information channels and members of the social system associated with the aerospace knowledge diffusion process, placing particular emphasis on aerospace librarians as information intermediaries.

  5. 32nd Aerospace Mechanisms Symposium

    NASA Technical Reports Server (NTRS)

    Walker, S. W. (Compiler); Boesiger, Edward A. (Compiler)

    1998-01-01

    The proceedings of the 32nd Aerospace Mechanism Symposium are reported. NASA John F. Kennedy Space Center (KSC) hosted the symposium that was held at the Hilton Oceanfront Hotel in Cocoa Beach, Florida on May 13-15, 1998. The symposium was cosponsored by Lockheed Martin Missiles and Space and the Aerospace Mechanisms Symposium Committee. During these days, 28 papers were presented. Topics included robotics, deployment mechanisms, bearing, actuators, scanners, boom and antenna release, and test equipment.

  6. Women, Innovation and Aerospace Event

    NASA Image and Video Library

    2012-03-08

    Catherine Didion, Senior Fellow, National Academy of Engineering, participates in a panel discussion at the Women, Innovation and Aerospace event celebrating Women's History Month at the George Washington University Jack Morton Auditorium, Thursday, March 8, 2012 in Washington. The WIA day-long event will help to foster a discussion for students and early career professionals about how to continue to encourage women to enter and succeed in the field of aerospace. Photo Credit: (NASA/Carla Cioffi)

  7. Women, Innovation and Aerospace Event

    NASA Image and Video Library

    2012-03-08

    Rebecca Spyke-Keiser, NASA's Associate Deputy Administrator for policy integration, gives opening remarks at the Women, Innovation and Aerospace event celebrating Women's History Month at the George Washington University Jack Morton Auditorium, Thursday, March 8, 2012 in Washington. The WIA day-long event will help to foster a discussion for students and early career professionals about how to continue to encourage women to enter and succeed in the field of aerospace. Photo Credit: (NASA/Carla Cioffi)

  8. Access to Japanese aerospace-related scientific and technical information: The NASA Aerospace Database

    NASA Technical Reports Server (NTRS)

    Hoetker, Glenn P.; Lahr, Thomas F.

    1993-01-01

    With Japan's growing R&D strength in aerospace-related fields, it is increasingly important for U.S. researchers to be aware of Japanese advances. However, several factors make it difficult to do so. After reviewing the diffusion of aerospace STI in Japan, four factors which make it difficult for U.S. researchers to gather this information are discussed: language, the human network, information scatter, and document acquisition. NASA activities to alleviate these difficulties are described, beginning with a general overview of the NASA STI Program. The effects of the new National Level Agreement between NASA and NASDA are discussed.

  9. Aerospace Nickel-cadmium Cell Verification

    NASA Technical Reports Server (NTRS)

    Manzo, Michelle A.; Strawn, D. Michael; Hall, Stephen W.

    2001-01-01

    During the early years of satellites, NASA successfully flew "NASA-Standard" nickel-cadmium (Ni-Cd) cells manufactured by GE/Gates/SAFF on a variety of spacecraft. In 1992 a NASA Battery Review Board determined that the strategy of a NASA Standard Cell and Battery Specification and the accompanying NASA control of a standard manufacturing control document (MCD) for Ni-Cd cells and batteries was unwarranted. As a result of that determination, standards were abandoned and the use of cells other than the NASA Standard was required. In order to gain insight into the performance and characteristics of the various aerospace Ni-Cd products available, tasks were initiated within the NASA Aerospace Flight Battery Systems Program that involved the procurement and testing of representative aerospace Ni-Cd cell designs. A standard set of test conditions was established in order to provide similar information about the products from various vendors. The objective of this testing was to provide independent verification of representative commercial flight cells available in the marketplace today. This paper will provide a summary of the verification tests run on cells from various manufacturers: Sanyo 35 Ampere-hour (Ali) standard and 35 Ali advanced Ni-Cd cells, SAFr 50 Ah Ni-Cd cells and Eagle-Picher 21 Ali Magnum and 21 Ali Super Ni-CdTM cells from Eagle-Picher were put through a full evaluation. A limited number of 18 and 55 Ali cells from Acme Electric were also tested to provide an initial evaluation of the Acme aerospace cell designs. Additionally, 35 Ali aerospace design Ni-MH cells from Sanyo were evaluated under the standard conditions established for this program. Ile test program is essentially complete. The cell design parameters, the verification test plan and the details of the test result will be discussed.

  10. NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 34: How early career-stage US aerospace engineers and scientists produce and use information

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.

    1995-01-01

    The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis the production and use of information by U.S. aerospace engineers and scientists who had changed their American Institute of Aeronautics and Astronautics (AIAA) membership from student to professional in the past five years.

  11. Serum Lp-PLA2: as a novel viewpoint in periodontal treatment of hyperlipidaemics.

    PubMed

    Fentoğlu, Özlem; Kirzioğlu, Fatma Yeşim; Tözüm Bulut, Memduha; Kurgan, Şivge; Koçak, Havva; Sütcü, Recep; Kale Köroğlu, Banu; Günhan, Meral

    2015-01-01

    To evaluate the effects of periodontal treatment on serum lipoprotein-associated phospholipase A2 (Lp-PLA2) and C-reactive protein (CRP) levels in hyperlipidaemic patients with periodontitis. The study included 52 hyperlipidaemics and 28 systemically healthy controls (C) with periodontitis. Of the 52 hyperlipidaemics, 29 received a suggested diet (HD), and 23 of them were prescribed statin (HS). Clinical periodontal parameters, serum lipids, Lp-PLA2, and CRP levels were assessed at the baseline and 2 months after the completion of the nonsurgical periodontal treatment (2MPT). Serum parameters were also evaluated 1 week following the periodontal treatment (1WPT). At the baseline, patients in the HS group had a higher percentage of bleeding on probing than those in the C and HD groups. Hyperlipidaemics had higher serum triglyceride levels than the control group at 2MPT compared to the baseline. At 2MPT, the levels of Lp-PLA2 in the HS group were significantly higher compared to the baseline and 1WPT. There were no statistically significant differences in CRP levels between study periods for all groups. The periodontal treatment may affect the inflammatory control of hyperlipidaemic patients with periodontitis via increased Lp-PLA2 levels and severity of the impaired lipid metabolism. These findings may be important regarding the therapeutic strategies for hyperlipidaemics with periodontitis.

  12. An international aerospace information system: A cooperative opportunity

    NASA Technical Reports Server (NTRS)

    Cotter, Gladys A.; Blados, Walter R.

    1992-01-01

    Scientific and technical information (STI) is a valuable resource which represents the results of large investments in research and development (R&D), and the expertise of a nation. NASA and its predecessor organizations have developed and managed the preeminent aerospace information system. We see information and information systems changing and becoming more international in scope. In Europe, consistent with joint R&D programs and a view toward a united Europe, we have seen the emergence of a European Aerospace Database concept. In addition, the development of aeronautics and astronautics in individual nations have also lead to initiatives for national aerospace databases. Considering recent technological developments in information science and technology, as well as the reality of scarce resources in all nations, it is time to reconsider the mutually beneficial possibilities offered by cooperation and international resource sharing. The new possibilities offered through cooperation among the various aerospace database efforts toward an international aerospace database initiative which can optimize the cost/benefit equation for all participants are considered.

  13. Aerospace Technology Careers: The Opportunity To Soar. Information Summaries.

    ERIC Educational Resources Information Center

    National Aeronautics and Space Administration, Washington, DC.

    This document provides guidelines for the preparation of careers in aerospace, whether with the National Aeronautics and Space Administration (NASA) or private industry. The document discusses the following topics: (1) Preparing for an Aerospace Career; (2) Careers in Aerospace; (3) Employment Requirements; and (4) How To Apply. (ZWH)

  14. NASA/DoD Aerospace Knowledge Diffusion Research Project. Paper 30: The electronic transfer of information and aerospace knowledge diffusion

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Bishop, Ann P.; Barclay, Rebecca O.; Kennedy, John M.

    1992-01-01

    Increasing reliance on and investment in information technology and electronic networking systems presupposes that computing and information technology will play a major role in the diffusion of aerospace knowledge. Little is known, however, about actual information technology needs, uses, and problems within the aerospace knowledge diffusion process. The authors state that the potential contributions of information technology to increased productivity and competitiveness will be diminished unless empirically derived knowledge regarding the information-seeking behavior of the members of the social system - those who are producing, transferring, and using scientific and technical information - is incorporated into a new technology policy framework. Research into the use of information technology and electronic networks by U.S. aerospace engineers and scientists, collected as part of a research project designed to study aerospace knowledge diffusion, is presented in support of this assertion.

  15. Aerosol Correction for Improving OMPS/LP Ozone Retrieval

    NASA Technical Reports Server (NTRS)

    Chen, Zhong; Bhartia, Pawan K.; Loughman, Robert

    2015-01-01

    The Ozone Mapping and Profiler Suite Limb Profiler (OMPS-LP) on board the Suomi National Polar-orbiting Partnership (SNPP) satellite was launched on Oct. 28, 2011. Limb profilers measures the radiance scattered from the Earth's atmospheric in limb viewing mode from 290 to 1000 nm and infer ozone profiles from tropopause to 60 km. The recently released OMPS-LP Version 2 data product contains the first publicly released ozone profiles retrievals, and these are now available for the entire OMPS mission, which extends from April, 2012. The Version 2 data product retrievals incorporate several important improvements to the algorithm. One of the primary changes is to turn off the aerosol retrieval module. The aerosol profiles retrieved inside the ozone code was not helping the ozone retrieval and was adding noise and other artifacts. Aerosols including polar stratospheric cloud (PSC) and polar mesospheric clouds (PMC) have a detectable effect on OMPS-LP data. Our results show that ignoring the aerosol contribution would produce an ozone density bias of up to 10 percent in the region of maximum aerosol extinction. Therefore, aerosol correction is needed to improve the quality of the retrieved ozone concentration profile. We provide Aerosol Scattering Index (ASI) for detecting aerosols-PMC-PSC, defined as ln(Im-Ic) normalized at 45km, where Im is the measured radiance and Ic is the calculated radiance assuming no aerosols. Since ASI varies with wavelengths, latitude and altitude, we can start by assuming no aerosol profiles in calculating the ASIs and then use the aerosol profile to see if it significantly reduces the residuals. We also discuss the effect of aerosol size distribution on the ozone profile retrieval process. Finally, we present an aerosol-PMC-PSC correction scheme.

  16. NASA/DoD Aerospace Knowledge Diffusion Research Project. XXVI - The relationship between technology policy and scientific and technical information within the U.S. and Japanese aerospace industries

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Lahr, Tom; Hoetker, Glenn

    1993-01-01

    Government technology policy has nurtured the growth of the aerospace industry, which is vital to both the U.S. and Japanese economies. Japanese technology policy differs significantly from U.S. technology policy, however, particularly with respect to the production, transfer, and use of scientific and technical information (STI). In this paper, we discuss the unique position of the aerospace industry in the U.S. and Japan, U.S. and Japanese aerospace policy, and the role of STI in the process of aerospace innovation. The information-seeking behaviors of U.S. and Japanese aerospace engineers and scientists are compared. The authors advocate the development of innovation-adoption technology and STI policy goals for U.S. aerospace and the inclusion of an aerospace knowledge diffusion transfer system with an 'active' component for scanning and acquiring foreign aerospace technology and STI.

  17. 77 FR 45596 - Shell Energy North America (US), L.P. v. California Independent System Operator Corporation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-01

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL12-88 -000] Shell Energy North America (US), L.P. v. California Independent System Operator Corporation; Notice of Complaint Take... (Commission) Rules of Practice and Procedure, 18 CFR 385.206, Shell Energy North America (US), L.P...

  18. 78 FR 3495 - Claritas Capital Specialty Debt II, L.P.; Application No. 99000779; Notice Seeking Exemption...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-16

    ... SMALL BUSINESS ADMINISTRATION Claritas Capital Specialty Debt II, L.P.; Application No. 99000779; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Claritas Capital Specialty Debt II, L.P., 30 Burton Hills Blvd., Suite 100...

  19. 77 FR 25133 - Foreign-Trade Zone 126, Temporary/Interim Manufacturing Authority, Brightpoint North America L.P...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket T-3-2012] Foreign-Trade Zone 126, Temporary/Interim Manufacturing Authority, Brightpoint North America L.P. (Cell Phone Kitting and... America L.P., to produce cell phone kits under FTZ procedures within FTZ 126--Site 23, in Reno, Nevada...

  20. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 11: The Voice of the User: How US Aerospace Engineers and Scientists View DoD Technical Reports

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Kennedy, John M.

    1991-01-01

    The project examines how the results of NASA/DOD research diffuse into the aerospace R&D process, and empirically analyzes the implications of the aerospace knowledge diffusion process. Specific issues considered are the roles played by government technical reports, the recognition of the value of scientific and technical information (STI), and the optimization of the STI aerospace transfer system. Information-seeking habits are assessed for the U.S. aerospace community, the general community, the academic sector, and the international community. U.S. aerospace engineers and scientists use 65 percent of working time to communicate STI, and prefer 'internal' STI over 'external' STI. The isolation from 'external' information is found to be detrimental to U.S. aerospace R&D in general.

  1. Lp-PLA2 activity is associated with increased risk of diabetic retinopathy: a longitudinal disease progression study.

    PubMed

    Siddiqui, Moneeza K; Kennedy, Gwen; Carr, Fiona; Doney, Alexander S F; Pearson, Ewan R; Morris, Andrew D; Johnson, Toby; McLaughlin, Megan M; Williams, Rachel E; Palmer, Colin N A

    2018-06-01

    The aim of the study was to examine the association between lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) activity levels and incident diabetic retinopathy and change in retinopathy grade. This was a cohort study of diabetic participants with serum collected at baseline and routinely collected diabetic retinal screening data. Participants with type 2 diabetes from the GoDARTS (Genetics of Diabetes Audit and Research in Tayside Scotland) cohort were used. This cohort is composed of individuals of white Scottish ancestry from the Tayside region of Scotland. Survival analysis accounting for informative censoring by modelling death as a competing risk was performed for the development of incident diabetic retinopathy from a disease-free state in a 3 year follow-up period (n = 1364) by stratified Lp-PLA 2 activity levels (in quartiles). The same analysis was performed for transitions to more severe grades. The hazard of developing incident diabetic retinopathy was 2.08 times higher (95% CI 1.64, 2.63) for the highest quartile of Lp-PLA 2 activity compared with the lowest. Higher Lp-PLA 2 activity levels were associated with a significantly increased risk for transitions to all grades. The hazards of developing observable (or more severe) and referable (or more severe) retinopathy were 2.82 (95% CI 1.71, 4.65) and 1.87 (95% CI 1.26, 2.77) times higher for the highest quartile of Lp-PLA 2 activity compared with the lowest, respectively. Higher Lp-PLA 2 levels are associated with increased risk of death and the development of incident diabetic retinopathy, as well as transitions to more severe grades of diabetic retinopathy. These associations are independent of calculated LDL-cholesterol and other traditional risk factors. Further, this biomarker study shows that the association is temporally sensitive to the proximity of the event to measurement of Lp-PLA 2.

  2. NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 14: Engineering work and information use in aerospace: Results of a telephone survey

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Kennedy, John M.; White, Terry F.

    1992-01-01

    A telephone survey of U.S. aerospace engineers and scientists who were on the Society of Automotive Engineers (SAE) mailing list was conducted between August 14-26, 1991. The survey was undertaken to obtain information on the daily work activities of aerospace engineers and scientists, to measure various practices used by aerospace engineers and scientists to obtain STI, and to ask aerospace engineers and scientists about their use of electronic networks. Co-workers were found important sources of information. Co-workers are used to obtain technical information because the information they have is relevant, not because co-workers are accessible. As technical uncertainty increases, so does the need for information internal and external to the organization. Electronic networks enjoy widespread use within the aerospace community. These networks are accessible and they are used to contact people at remote sites. About 80 percent of the respondents used electronic mail, file transfer, and information or data retrieval to commercial or in-house data bases.

  3. The 29th Aerospace Mechanisms Symposium

    NASA Technical Reports Server (NTRS)

    Schneider, William C. (Editor)

    1995-01-01

    The proceedings of the 29th Aerospace Mechanisms Symposium, which was hosted by NASA Johnson Space Center and held at the South Shore Harbour Conference Facility on May 17-19, 1995, are reported. Technological areas covered include actuators, aerospace mechanism applications for ground support equipment, lubricants, pointing mechanisms joints, bearings, release devices, booms, robotic mechanisms, and other mechanisms for spacecraft.

  4. The 28th Aerospace Mechanisms Symposium

    NASA Technical Reports Server (NTRS)

    Rohn, Douglas A. (Compiler)

    1994-01-01

    The proceedings of the 28th Aerospace Mechanisms Symposium, which was hosted by the NASA Lewis Research Center and held at the Cleveland Marriott Society Center on May 18, 19, and 20, 1994, are reported. Technological areas covered include actuators, aerospace mechanism applications for ground support equipment, lubricants, pointing mechanisms joints, bearings, release devices, booms, robotic mechanisms, and other mechanisms for spacecraft.

  5. Women, Innovation and Aerospace Event

    NASA Image and Video Library

    2012-03-08

    Kathy Sullivan, NOAA (National Oceanic and Atmospheric Administration) Deputy Administrator and former NASA astronaut, participates in a panel discussion at the Women, Innovation and Aerospace event celebrating Women's History Month at the George Washington University Jack Morton Auditorium, Thursday, March 8, 2012 in Washington. The WIA day-long event will help to foster a discussion for students and early career professionals about how to continue to encourage women to enter and succeed in the field of aerospace. Photo Credit: (NASA/Carla Cioffi)

  6. Women, Innovation and Aerospace Event

    NASA Image and Video Library

    2012-03-08

    Veronica Villalobos, Director, Office of Diversity and Inclusion, Office of Personnel Management, participates in a panel discussion at the Women, Innovation and Aerospace event celebrating Women's History Month at the George Washington University Jack Morton Auditorium, Thursday, March 8, 2012 in Washington. The WIA day-long event will help to foster a discussion for students and early career professionals about how to continue to encourage women to enter and succeed in the field of aerospace. Photo Credit: (NASA/Carla Cioffi)

  7. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 14: An analysis of the technical communications practices reported by Israeli and US aerospace engineers and scientists

    NASA Technical Reports Server (NTRS)

    Barclay, Rebecca O.; Pinelli, Thomas E.; Elazar, David; Kennedy, John M.

    1991-01-01

    As part of Phase 4 of the NASA/DoD Aerospace Knowledge Diffusion Research Project, two pilot studies were conducted that investigated the technical communications practices of Israeli and U.S. aerospace engineers and scientists. Both studies had the same five objectives: first, to solicit the opinions of aerospace engineers and scientists regarding the importance of technical communications to their profession; second, to determine the use and production of technical communications by aerospace engineers and scientists; third, to seek their view about the appropriate content of an undergraduate course in technical communications; fourth, to determine aerospace engineers' and scientists' use of libraries, technical information centers, and on-line databases; and fifth, to determine the use and importance of computer and information technology to them. A self-administered questionnaire was mailed to randomly selected U.S. aerospace engineers and scientists who are working in cryogenics, adaptive walls, and magnetic suspension. A slightly modified version was sent to Israeli aerospace engineers and scientists working at Israel Aircraft Industries, LTD. Responses of the Israeli and U.S. aerospace engineers and scientists to selected questions are presented in this paper.

  8. Wireless Sensing Opportunities for Aerospace Applications

    NASA Technical Reports Server (NTRS)

    Wilson, William; Atkinson, Gary

    2007-01-01

    Wireless sensors and sensor networks is an emerging technology area with many applications within the aerospace industry. Integrated vehicle health monitoring (IVHM) of aerospace vehicles is needed to ensure the safety of the crew and the vehicle, yet often high costs, weight, size and other constraints prevent the incorporation of instrumentation onto spacecraft. This paper presents a few of the areas such as IVHM, where new wireless sensing technology is needed on both existing vehicles as well as future spacecraft. From ground tests to inflatable structures to the International Space Station, many applications could receive benefits from small, low power, wireless sensors. This paper also highlights some of the challenges that need to overcome when implementing wireless sensor networks for aerospace vehicles.

  9. Knowledge-based diagnosis for aerospace systems

    NASA Technical Reports Server (NTRS)

    Atkinson, David J.

    1988-01-01

    The need for automated diagnosis in aerospace systems and the approach of using knowledge-based systems are examined. Research issues in knowledge-based diagnosis which are important for aerospace applications are treated along with a review of recent relevant research developments in Artificial Intelligence. The design and operation of some existing knowledge-based diagnosis systems are described. The systems described and compared include the LES expert system for liquid oxygen loading at NASA Kennedy Space Center, the FAITH diagnosis system developed at the Jet Propulsion Laboratory, the PES procedural expert system developed at SRI International, the CSRL approach developed at Ohio State University, the StarPlan system developed by Ford Aerospace, the IDM integrated diagnostic model, and the DRAPhys diagnostic system developed at NASA Langley Research Center.

  10. Conservation of Strategic Aerospace Materials (COSAM)

    NASA Technical Reports Server (NTRS)

    Stephens, J. R.

    1981-01-01

    Research efforts to reduce the dependence of the aerospace industry on strategic metals, such as cobalt (Co), columbium (Cb), tantalum (Ta), and chromium (Cr), by providing the materials technology needed to minimize the strategic metal content of critical aerospace components for gas turbine engines are addressed. Thrusts in three technology areas are identified: near term activities in the area of strategic element substitution; intermediate-range activities in the area of materials processing; and long term, high risk activities in the area of 'new classes' of high temprature metallic materials. Specifically, the role of cobalt in nickel-base and cobalt-base superalloys vital to the aerospace industry is examined along with the mechanical and physical properties of intermetallics that will contain a minimum of the stragetic metals.

  11. Aerospace Environmental Technology Conference

    NASA Technical Reports Server (NTRS)

    Whitaker, A. F. (Editor)

    1995-01-01

    The mandated elimination of CFC's, Halons, TCA, and other ozone depleting chemicals and specific hazardous materials has required changes and new developments in aerospace materials and processes. The aerospace industry has been involved for several years in providing product substitutions, redesigning entire production processes, and developing new materials that minimize or eliminate damage to the environment. These activities emphasize replacement cleaning solvents and their application verifications, compliant coatings including corrosion protection systems, and removal techniques, chemical propulsion effects on the environment, and the initiation of modifications to relevant processing and manufacturing specifications and standards. The Executive Summary of this Conference is published as NASA CP-3297.

  12. 76 FR 68745 - Seneca Power Partners, L.P.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL12-6-000] Seneca Power... October 27, 2011, pursuant to sections 206 and 306 of the Federal Power Act, 16 U.S.C. 824e and 825e and..., 18 CFR 385.206, Seneca Power Partners, L.P. (Complainant) filed a complaint against the New York...

  13. 32 CFR 705.30 - Aerospace Education Workshop.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Aerospace Education Workshop. 705.30 Section 705... REGULATIONS AND OFFICIAL RECORDS PUBLIC AFFAIRS REGULATIONS § 705.30 Aerospace Education Workshop. (a) This... education programs. (b) Appropriate commands are encouraged to provide assistance to educational...

  14. Aerospace Resources for Science and Technology Education.

    ERIC Educational Resources Information Center

    Maley, Donald, Ed.; Smith, Kenneth L., Ed.

    This publication on Aerospace Programs is a special edition of "Technology Education" featuring descriptions of 15 select aerospace education programs from diverse localities spanning the full range of instructional levels. Following introductory material, the monograph contains the following largely unedited program descriptions: (1)…

  15. 32 CFR 705.30 - Aerospace Education Workshop.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Aerospace Education Workshop. 705.30 Section 705... REGULATIONS AND OFFICIAL RECORDS PUBLIC AFFAIRS REGULATIONS § 705.30 Aerospace Education Workshop. (a) This... education programs. (b) Appropriate commands are encouraged to provide assistance to educational...

  16. Learning to perceive and recognize a second language: the L2LP model revised.

    PubMed

    van Leussen, Jan-Willem; Escudero, Paola

    2015-01-01

    We present a test of a revised version of the Second Language Linguistic Perception (L2LP) model, a computational model of the acquisition of second language (L2) speech perception and recognition. The model draws on phonetic, phonological, and psycholinguistic constructs to explain a number of L2 learning scenarios. However, a recent computational implementation failed to validate a theoretical proposal for a learning scenario where the L2 has less phonemic categories than the native language (L1) along a given acoustic continuum. According to the L2LP, learners faced with this learning scenario must not only shift their old L1 phoneme boundaries but also reduce the number of categories employed in perception. Our proposed revision to L2LP successfully accounts for this updating in the number of perceptual categories as a process driven by the meaning of lexical items, rather than by the learners' awareness of the number and type of phonemes that are relevant in their new language, as the previous version of L2LP assumed. Results of our simulations show that meaning-driven learning correctly predicts the developmental path of L2 phoneme perception seen in empirical studies. Additionally, and to contribute to a long-standing debate in psycholinguistics, we test two versions of the model, with the stages of phonemic perception and lexical recognition being either sequential or interactive. Both versions succeed in learning to recognize minimal pairs in the new L2, but make diverging predictions on learners' resulting phonological representations. In sum, the proposed revision to the L2LP model contributes to our understanding of L2 acquisition, with implications for speech processing in general.

  17. Engineering in the 21st century. [aerospace technology prospects

    NASA Technical Reports Server (NTRS)

    Mccarthy, J. F., Jr.

    1978-01-01

    A description is presented of the nature of the aerospace technology system that might be expected by the 21st century from a reasonable evolution of the current resources and capabilities. An aerospace employment outlook is provided. The years 1977 and 1978 seem to be marking the beginning of a period of stability and moderate growth in the aerospace industry. Aerospace research and development employment increased to 70,000 in 1977 and is now occupying a near-constant 18% share of the total research and development work force. The changing job environment is considered along with the future of aerospace education. It is found that one trend is toward a more interdisciplinary education. Most trend setters in engineering education recognize that the really challenging engineering problems invariably require the judicious exercise of several disciplines for their solution. Some future trends in aerospace technology are discussed. By the year 2000 space technology will have achieved major advances in four areas, including management of information, transportation, space structures, and energy.

  18. Recent advances in aerospace composite NDE

    NASA Astrophysics Data System (ADS)

    Georgeson, Gary E.

    2002-06-01

    As the aerospace industry continues to advance the design and use of composite structure, the NDE community faces the difficulties of trying to keep up. The challenges lie in manufacturing evaluation of the newest aerospace structures and materials and the in-service inspection and monitoring of damaged or aging composites. This paper provides examples of several promising NDI applications in the world of aerospace composites. Airborne (or non-contact) Ultrasonic Testing (UT) has been available for decades, but recently has generated new interest due to significant improvements in transducer design and low noise electronics. Boeing is developing inspection techniques for composite joints and core blankets using this technology. In-service inspection techniques for thick, multi-layer structures are also being advanced. One effective technique integrates the S-9 Sondicator, a traditional bond testing device, with Boeing's Mobile Automated Scanner (MAUS) platform. Composite patches have seen limited use on-aircraft, due, in part, to the difficulty of determining the quality of a bonded joint. A unique approach using Electronic Speckle Pattern Interferometry (ESPI) is showing promise as a bonded patch-inspection method. Other NDI techniques currently being developed for aerospace application are also briefly discussed.

  19. 75 FR 17706 - Flint Hills Resources, LP, Complainant v. Mid-America Pipeline Company, LLC, Respondent; Notice...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-07

    ... Resources, LP, Complainant v. Mid-America Pipeline Company, LLC, Respondent; Notice of Complaint March 29... Interstate Commerce Act, 49 U.S.C. App. 2, 3, 13, and 15 (1988), Flint Hills Resources, LP (Complainant... ``eSubscription'' link on the Web site that enables subscribers to receive e-mail notification when a...

  20. NASA Elementary Aerospace Activities Free to Members

    ERIC Educational Resources Information Center

    Journal of Aerospace Education, 1978

    1978-01-01

    Describes the contents of Elementary School Aerospace Activities: A Resource for Teachers. Activities examine a variety of topics in aerospace education and are intended to be used with children ages 5-11. The book is available from the Government Printing Office (GPO) for $3.00. (CP)

  1. An international aerospace information system - A cooperative opportunity

    NASA Technical Reports Server (NTRS)

    Blados, Walter R.; Cotter, Gladys A.

    1992-01-01

    This paper presents for consideration new possibilities for uniting the various aerospace database efforts toward a cooperative international aerospace database initiative that can optimize the cost-benefit equation for all members. The development of astronautics and aeronautics in individual nations has led to initiatives for national aerospace databases. Technological developments in information technology and science, as well as the reality of scarce resources, makes it necessary to reconsider the mutually beneficial possibilities offered by cooperation and international resource sharing.

  2. Challenges in aerospace medicine education.

    PubMed

    Grenon, S Marlene; Saary, Joan

    2011-11-01

    Aerospace medicine training and research represents a dream for many and a challenge for most. In Canada, although some opportunities exist for the pursuit of education and research in the aerospace medicine field, they are limited despite the importance of this field for enabling safe human space exploration. In this commentary, we aim to identify some of the challenges facing individuals wishing to get involved in the field as well as the causal factors for these challenges. We also explore strategies to mitigate against these.

  3. Advanced Engineering Environments: Implications for Aerospace Manufacturing

    NASA Technical Reports Server (NTRS)

    Thomas, D.

    2001-01-01

    There are significant challenges facing today's aerospace industry. Global competition, more complex products, geographically-distributed design teams, demands for lower cost, higher reliability and safer vehicles, and the need to incorporate the latest technologies quicker all face the developer of aerospace systems. New information technologies offer promising opportunities to develop advanced engineering environments (AEEs) to meet these challenges. Significant advances in the state-of-the-art of aerospace engineering practice are envisioned in the areas of engineering design and analytical tools, cost and risk tools, collaborative engineering, and high-fidelity simulations early in the development cycle. These advances will enable modeling and simulation of manufacturing methods, which will in turn allow manufacturing considerations to be included much earlier in the system development cycle. Significant cost savings, increased quality, and decreased manufacturing cycle time are expected to result. This paper will give an overview of the NASA's Intelligent Synthesis Environment, the agency initiative to develop an AEE, with a focus on the anticipated benefits in aerospace manufacturing.

  4. Probability and Statistics in Aerospace Engineering

    NASA Technical Reports Server (NTRS)

    Rheinfurth, M. H.; Howell, L. W.

    1998-01-01

    This monograph was prepared to give the practicing engineer a clear understanding of probability and statistics with special consideration to problems frequently encountered in aerospace engineering. It is conceived to be both a desktop reference and a refresher for aerospace engineers in government and industry. It could also be used as a supplement to standard texts for in-house training courses on the subject.

  5. Acting Administrator Lightfoot Visits Ball Aerospace

    NASA Image and Video Library

    2017-04-06

    Michael Dean, senior project engineer for the Joint Polar Satellite System (JPSS) program at Ball Aerospace, right, speaks with acting NASA Deputy Administrator Lesa Roe, second from left, and acting NASA Administrator Robert Lightfoot, center, about the 20ft. by 24 ft. vertical thermal vacuum chamber, Thursday, April 6, 2017 during a visit to Ball Aerospace in Boulder, Colo. Photo Credit: (NASA/Joel Kowsky)

  6. The 2001 NASA Aerospace Battery Workshop

    NASA Technical Reports Server (NTRS)

    Brewer, Jeff C. (Compiler)

    2002-01-01

    This document contains the proceedings of the 34th annual NASA Aerospace Battery Workshop, hosted by the Marshall Space Flight Center, November 27-29, 2001. The workshop was attended by scientists and engineers from various agencies of the US Government, aerospace contractors, and battery manufacturers, as well as international participation in like kind. The subjects covered included nickel-hydrogen, nickel-cadmium, lithium-ion, and silver-zinc technologies.

  7. Aero-space plane figures of merit

    NASA Technical Reports Server (NTRS)

    Hunt, James L.; Martin, John G.

    1992-01-01

    The design environment of the aerospace plane is variable rich, intricately networked and sensitivity intensive. To achieve a viable design necessitates addressing three principal elements: knowledge of the 'figures of merit' and their relationships, the synthesis procedure, and the synergistic integration of advanced technologies across the discipline spectrum. This paper focuses on the 'figures of merit' that create the design of an aerospace plane.

  8. Index of aerospace mechanisms symposia proceedings 1-19

    NASA Technical Reports Server (NTRS)

    Rinaldo, A.; Wilson, J.

    1986-01-01

    This index, organized in five sections (by symposium, by title, by author, by subject, and by project), brings together information on the first 19 Aerospace Mechanisms symposia. Key words are included, cross-referencing all the symposia, and the eighteenth and nineteenth symposia are cross-indexed by project. The Aerospace Mechanisms symposia are devoted to discussions of design, fabrication, test, and operational use of aerospace mechanisms; this is the first index that compiles information on symposia held from 1966 through 1985.

  9. Guides to Aerospace Research and Development in NATO Countries.

    DTIC Science & Technology

    1984-01-01

    The directory contains worldwide information Administrations et Services Aeroautiques. Designadores de Empresas Explotadoras about aviation/aerospace...ADVISORY GROUP FOR AEROSPACE RESEARCH AND DEVELOPMENT (ORGANISATION DU TRAITE DE L’ATLANTIQUE NORD) AGARD Report No.7 18 * GUIDES TO AEROSPACE RESEARCH...and transport containing also The Tithe and Keyword Index includes titles of all establishments listed in this highly professional photographs received

  10. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 21: Technological innovation and technical communications: Their place in aerospace engineering curricula. A survey of European, Japanese, and US Aerospace Engineers and Scientists

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Holland, Maurita Peterson; Keene, Michael L.; Kennedy, John M.

    1991-01-01

    Aerospace engineers and scientists from Western Europe, Japan, and the United States were surveyed as part of the NASA/DoD Aerospace Knowledge Diffusion Research Project. Questionnaires were used to solicit their opinions regarding the following: (1) the importance of technical communications to their profession; (2) the use and production of technical communications; and (3) their views about the appropriate content of an undergraduate course in technical communications. The ability to communicate technical information effectively was very important to the aerospace engineers and scientists who participated in the study. A considerable portion of their working week is devoted to using and producing technical information. The types of technical communications used and produced varied within and among the three groups. The type of technical communication product used and produced appears to be related to respondents' professional duties. Respondents from the three groups made similar recommendations regarding the principles, mechanics, and on-the-job communications to be included in an undergraduate technical communications course for aerospace majors.

  11. Common Cause Failure Modeling: Aerospace Versus Nuclear

    NASA Technical Reports Server (NTRS)

    Stott, James E.; Britton, Paul; Ring, Robert W.; Hark, Frank; Hatfield, G. Spencer

    2010-01-01

    Aggregate nuclear plant failure data is used to produce generic common-cause factors that are specifically for use in the common-cause failure models of NUREG/CR-5485. Furthermore, the models presented in NUREG/CR-5485 are specifically designed to incorporate two significantly distinct assumptions about the methods of surveillance testing from whence this aggregate failure data came. What are the implications of using these NUREG generic factors to model the common-cause failures of aerospace systems? Herein, the implications of using the NUREG generic factors in the modeling of aerospace systems are investigated in detail and strong recommendations for modeling the common-cause failures of aerospace systems are given.

  12. Machine intelligence and autonomy for aerospace systems

    NASA Technical Reports Server (NTRS)

    Heer, Ewald (Editor); Lum, Henry (Editor)

    1988-01-01

    The present volume discusses progress toward intelligent robot systems in aerospace applications, NASA Space Program automation and robotics efforts, the supervisory control of telerobotics in space, machine intelligence and crew/vehicle interfaces, expert-system terms and building tools, and knowledge-acquisition for autonomous systems. Also discussed are methods for validation of knowledge-based systems, a design methodology for knowledge-based management systems, knowledge-based simulation for aerospace systems, knowledge-based diagnosis, planning and scheduling methods in AI, the treatment of uncertainty in AI, vision-sensing techniques in aerospace applications, image-understanding techniques, tactile sensing for robots, distributed sensor integration, and the control of articulated and deformable space structures.

  13. Effects of topography and crustal heterogeneities on the source estimation of LP event at Kilauea volcano

    USGS Publications Warehouse

    Cesca, S.; Battaglia, J.; Dahm, T.; Tessmer, E.; Heimann, S.; Okubo, P.

    2008-01-01

    The main goal of this study is to improve the modelling of the source mechanism associated with the generation of long period (LP) signals in volcanic areas. Our intent is to evaluate the effects that detailed structural features of the volcanic models play in the generation of LP signal and the consequent retrieval of LP source characteristics. In particular, effects associated with the presence of topography and crustal heterogeneities are here studied in detail. We focus our study on a LP event observed at Kilauea volcano, Hawaii, in 2001 May. A detailed analysis of this event and its source modelling is accompanied by a set of synthetic tests, which aim to evaluate the effects of topography and the presence of low velocity shallow layers in the source region. The forward problem of Green's function generation is solved numerically following a pseudo-spectral approach, assuming different 3-D models. The inversion is done in the frequency domain and the resulting source mechanism is represented by the sum of two time-dependent terms: a full moment tensor and a single force. Synthetic tests show how characteristic velocity structures, associated with shallow sources, may be partially responsible for the generation of the observed long-lasting ringing waveforms. When applying the inversion technique to Kilauea LP data set, inversions carried out for different crustal models led to very similar source geometries, indicating a subhorizontal cracks. On the other hand, the source time function and its duration are significantly different for different models. These results support the indication of a strong influence of crustal layering on the generation of the LP signal, while the assumption of homogeneous velocity model may bring to misleading results. ?? 2008 The Authors Journal compilation ?? 2008 RAS.

  14. Immune-Enhancing Effect of Nanometric Lactobacillus plantarum nF1 (nLp-nF1) in a Mouse Model of Cyclophosphamide-Induced Immunosuppression.

    PubMed

    Choi, Dae-Woon; Jung, Sun Young; Kang, Jisu; Nam, Young-Do; Lim, Seong-Il; Kim, Ki Tae; Shin, Hee Soon

    2018-02-28

    Nanometric Lactobacillus plantarum nF1 (nLp-nF1) is a biogenics consisting of dead L. plantarum cells pretreated with heat and a nanodispersion process. In this study, we investigated the immune-enhancing effects of nLp-nF1 in vivo and in vitro. To evaluate the immunostimulatory effects of nLp-nF1, mice immunosuppressed by cyclophosphamide (CPP) treatment were administered with nLp-nF1. As expected, CPP restricted the immune response of mice, whereas oral administration of nLp-nF1 significantly increased the total IgG in the serum, and cytokine production (interleukin-12 (IL-12) and tumor necrosis factor alpha (TNF-α)) in bone marrow cells. Furthermore, nLp-nF1 enhanced the production of splenic cytokines such as IL-12, TNF-α, and interferon gamma (IFN-γ). In vitro, nLp-nF1 stimulated the immune response by enhancing the production of cytokines such as IL-12, TNF-α, and IFN-γ. Moreover, nLp-nF1 given a food additive enhanced the immune responses when combined with various food materials in vitro. These results suggest that nLp-nF1 could be used to strengthen the immune system and recover normal immunity in people with a weak immune system, such as children, the elderly, and patients.

  15. Women, Innovation and Aerospace Event

    NASA Image and Video Library

    2012-03-08

    Kathy Sullivan, right, NOAA (National Oceanic and Atmospheric Administration) Deputy Administrator and former NASA astronaut, participates in a panel discussion at the Women, Innovation and Aerospace event celebrating Women's History Month at the George Washington University Jack Morton Auditorium, Thursday, March 8, 2012 in Washington. Sullivan is joined by Catherine Didion, Senior Fellow, National Academy of Engineering. The WIA day-long event will help to foster a discussion for students and early career professionals about how to continue to encourage women to enter and succeed in the field of aerospace. Photo Credit: (NASA/Carla Cioffi)

  16. Second Aerospace Environmental Technology Conference

    NASA Technical Reports Server (NTRS)

    Whitaker, A. F. (Editor); Clark-Ingram, M. (Editor)

    1997-01-01

    The mandated elimination of CFC'S, Halons, TCA, and other ozone depleting chemicals and specific hazardous materials has required changes and new developments in aerospace materials and processes. The aerospace industry has been involved for several years in providing product substitutions, redesigning entire production processes, and developing new materials that minimize or eliminate damage to the environment. These activities emphasize replacement cleaning solvents and their application, verification, compliant coatings including corrosion protection system and removal techniques, chemical propulsion effects on the environment, and the initiation of modifications to relevant processing and manufacturing specifications and standards.

  17. Second Aerospace Environmental Technology Conference

    NASA Technical Reports Server (NTRS)

    Whitaker, A. F.; Clark-Ingram, M.; Hessler, S. L.

    1997-01-01

    The mandated elimination of CFC's, Halons, TCA, and other ozone depleting chemicals and specific hazardous materials has required changes and new developments in aerospace materials and processes. The aerospace industry has been involved for several years in providing product substitutions, redesigning entire production processes, and developing new materials that minimize or eliminate damage to the environment. These activities emphasize replacement cleaning solvents and their application verifications, compliant coatings including corrosion protection systems, and removal techniques, chemical propulsion effects on the environment, and the initiation of modifications to relevant processing and manufacturing specifications and standards.

  18. Aerospace Applications of Microprocessors

    NASA Technical Reports Server (NTRS)

    1980-01-01

    An assessment of the state of microprocessor applications is presented. Current and future requirements and associated technological advances which allow effective exploitation in aerospace applications are discussed.

  19. Synthesis and Structure-Activity Relationships of (-)-cis-N-Normetazocine-Based LP1 Derivatives.

    PubMed

    Pasquinucci, Lorella; Parenti, Carmela; Amata, Emanuele; Georgoussi, Zafiroula; Pallaki, Paschalina; Camarda, Valeria; Calò, Girolamo; Arena, Emanuela; Montenegro, Lucia; Turnaturi, Rita

    2018-05-05

    (−)- cis - N -Normetazocine represents a rigid scaffold able to mimic the tyramine moiety of endogenous opioid peptides, and the introduction of different N -substituents influences affinity and efficacy of respective ligands at MOR (mu opioid receptor), DOR (delta opioid receptor), and KOR (kappa opioid receptor). We have previously identified LP1, a MOR/DOR multitarget opioid ligand, with an N -phenylpropanamido substituent linked to (−)- cis - N -Normetazocine scaffold. Herein, we report the synthesis, competition binding and calcium mobilization assays of new compounds 10 ⁻ 16 that differ from LP1 by the nature of the N -substituent. In radioligand binding experiments, the compounds 10 ⁻ 13 , featured by an electron-withdrawing or electron-donating group in the para position of phenyl ring, displayed improved affinity for KOR (K i = 0.85⁻4.80 μM) in comparison to LP1 (7.5 μM). On the contrary, their MOR and DOR affinities were worse (K i = 0.18⁻0.28 μM and K i = 0.38⁻1.10 μM, respectively) with respect to LP1 values (K i = 0.049 and 0.033 μM). Analogous trends was recorded for the compounds 14 ⁻ 16 , featured by indoline, tetrahydroquinoline, and diphenylamine functionalities in the N -substituent. In calcium mobilization assays, the compound 10 with a p -fluorophenyl in the N -substituent shared the functional profile of LP1 (pEC 50 MOR = 7.01), although it was less active. Moreover, the p -methyl- ( 11 ) and p -cyano- ( 12 ) substituted compounds resulted in MOR partial agonists and DOR/KOR antagonists. By contrast, the derivatives 13 ⁻ 15 resulted as MOR antagonists, and the derivative 16 as a MOR/KOR antagonist (pK B MOR = 6.12 and pK B KOR = 6.11). Collectively, these data corroborated the critical role of the N -substituent in (−)- cis - N -Normetazocine scaffold. Thus, the new synthesized compounds could represent a template to achieve a specific agonist, antagonist, or mixed agonist/antagonist functional

  20. U.S. Aerospace and Aviation Industry: A State-By-State Analysis

    NASA Technical Reports Server (NTRS)

    2002-01-01

    President George W. Bush and the Congress created the Commission on the Future of the United States Aerospace Industry to evaluate the current and future health of the industry as well as the challenges that lie ahead for the U.S. workforce and the economy. To accomplish our mission, we commissioned a study on the economic impact of the aerospace industry nationally and on a state-by-state basis, using the best available U.S. government data. This study sought to define the core of the aerospace industry. The resulting data represents that very core those jobs specifically tied to commercial and civilian aerospace. U.S. Aerospace and Aviation: A State-by-State Analysis examines the civilian and commercial aerospace and aviation industry by employment, wages, payroll, and establishments. The report found that the U.S. civilian and commercial aerospace and aviation industry employed over 2 million workers in 2001.

  1. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 42: An analysis of the transfer of Scientific and Technical Information (STI) in the US aerospace industry

    NASA Technical Reports Server (NTRS)

    Kennedy, John M.; Pinelli, Thomas E.; Hecht, Laura F.; Barclay, Rebecca O.

    1994-01-01

    The U.S. aerospace industry has a long history of federal support for research related to its needs. Since the establishment of the National Advisory Committee for Aeronautics (NACA) in 1915, the federal government has provided continuous research support related to flight and aircraft design. This research has contributed to the international preeminence of the U.S. aerospace industry. In this paper, we present a sociological analysis of aerospace engineers and scientists and how their attitudes and behaviors impact the flow of scientific and technical information (STI). We use a constructivist framework to explain the spotty dissemination of federally funded aerospace research. Our research is aimed towards providing federal policymakers with a clearer understanding of how and when federally funded aerospace research is used. This understanding will help policymakers design improved information transfer systems that will aid the competitiveness of the U.S. aerospace industry.

  2. 78 FR 35625 - Sabine Pass Liquefaction Expansion, LLC; Sabine Pass Liquefaction, LLC; Sabine Pass LNG, L.P...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-13

    ... Pipeline, L.P.: Notice of Intent To Prepare an Environmental Assessment for the Planned Sabine Pass Liquefaction Expansion Project and Cheniere Creole Trail Pipeline Expansion Project, Request for Comments on... Expansion Project (SPLE Project) and the Cheniere Creole Trail Pipeline, L.P. (CCTPL) Chenier Creole Trail...

  3. NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 17: A comparison of the technical communication practices of Dutch and US aerospace engineers and scientists

    NASA Technical Reports Server (NTRS)

    Barclay, Rebecca O.; Pinelli, Thomas E.; Kennedy, John M.

    1993-01-01

    As part of Phase 4 of the NASA/DoD Aerospace Knowledge Diffusion Research Project, two studies were conducted that investigated the technical communications practices of Dutch and U.S. aerospace engineers and scientists. Both studies have the same seven objectives: first, to solicit the opinions of aerospace engineers and scientists regarding the importance of technical communications to their profession; second, to determine the use and production of technical communications by aerospace engineers and scientists; third, to seek their views about the appropriate content of an undergraduate course in technical communications; fourth, to determine aerospace engineers' and scientists' use of libraries, technical information centers, and on-line data bases; fifth, to determine the use and importance of computer and information technology to them; sixth, to determine their use of electronic networks; and seventh, to determine their use of foreign and domestically produced technical reports. A self-administered questionnaire was distributed to aerospace engineers and scientists at the National Aerospace Laboratory (NLR), and NASA Ames Research Center, and the NASA Langley Research Center. The completion rates for the Dutch and U.S. surveys were 55 and 61 percent, respectively. Responses of the Dutch and U.S. participants to selected questions are presented.

  4. Aerospace Medicine

    NASA Technical Reports Server (NTRS)

    Davis, Jeffrey R.

    2006-01-01

    This abstract describes the content of a presentation for ground rounds at Mt. Sinai School of Medicine. The presentation contains three sections. The first describes the history of aerospace medicine beginning with early flights with animals. The second section of the presentation describes current programs and planning for future missions. The third section describes the medical challenges of exploration missions.

  5. Optical Information Processing for Aerospace Applications 2

    NASA Technical Reports Server (NTRS)

    Stermer, R. L. (Compiler)

    1984-01-01

    Current research in optical processing, and determination of its role in future aerospace systems was reviewed. It is shown that optical processing offers significant potential for aircraft and spacecraft control, pattern recognition, and robotics. It is demonstrated that the development of optical devices and components can be implemented in practical aerospace configurations.

  6. Sparse filtering with the generalized lp/lq norm and its applications to the condition monitoring of rotating machinery

    NASA Astrophysics Data System (ADS)

    Jia, Xiaodong; Zhao, Ming; Di, Yuan; Li, Pin; Lee, Jay

    2018-03-01

    Sparsity is becoming a more and more important topic in the area of machine learning and signal processing recently. One big family of sparse measures in current literature is the generalized lp /lq norm, which is scale invariant and is widely regarded as normalized lp norm. However, the characteristics of the generalized lp /lq norm are still less discussed and its application to the condition monitoring of rotating devices has been still unexplored. In this study, we firstly discuss the characteristics of the generalized lp /lq norm for sparse optimization and then propose a method of sparse filtering with the generalized lp /lq norm for the purpose of impulsive signature enhancement. Further driven by the trend of industrial big data and the need of reducing maintenance cost for industrial equipment, the proposed sparse filter is customized for vibration signal processing and also implemented on bearing and gearbox for the purpose of condition monitoring. Based on the results from the industrial implementations in this paper, the proposed method has been found to be a promising tool for impulsive feature enhancement, and the superiority of the proposed method over previous methods is also demonstrated.

  7. Meaning and value of cloud manufacturing platform for aerospace enterprises

    NASA Astrophysics Data System (ADS)

    Tang, Wei; Xu, Wei; Xin, Xin

    2017-08-01

    Aerospace manufacturing engineering technology status it is important symbol to measure the comprehensive strength of nation. This paper analyzes the meaning and value of aerospace enterprises, based on the concept of cloud manufacturing to the practical production and application, combined with the characteristics of aerospace enterprises.

  8. Most significant reduction of cardiovascular events in patients undergoing lipoproteinapheresis due to raised Lp(a) levels - A multicenter observational study.

    PubMed

    Schatz, U; Tselmin, S; Müller, G; Julius, U; Hohenstein, B; Fischer, S; Bornstein, S R

    2017-11-01

    Lipoprotein(a) (Lp(a)) is an independent cardiovascular (CV) risk factor, predisposing to premature and progressive CV events. Lipoproteinapheresis (LA) is the only efficacious therapy for reducing Lp(a). Data comparing the clinical efficacy of LA with respect to reduction of CV events in subjects with elevated Lp(a) versus LDL-C versus both disorders is scarce. We aimed to perform this comparison in a multicenter observational study. 113 LA patients from 8 apheresis centers were included (mean age 56.3 years). They were divided into 3 groups: Group I: Lp(a) < 600 mg/l, LDL-C > 2.6 mmol/l, Group II: Lp(a) > 600 mg/l, LDL-C < 2.6 mmol/l, and Group III: Lp(a) > 600 mg/l, LDL-C > 2.6 mmol/l. CV events were documented 2 years before versus 2 years after LA start. Before start of LA Group II showed the highest CV event rate (p 0.001). Group III had a higher CV event rate than Group I (p 0.03). During LA there was a significant reduction of CV events/patient in all vessel beds (1.22 ± 1.16 versus 0.33 ± 0.75, p < 0.001). The highest CV event rate during LA was seen in coronaries followed by peripheral arteries, cerebrovascular events were least common. Greater CV event reduction rates were achieved in patients with isolated Lp(a) elevation (-77%, p < 0.001) and in patients with Lp(a) and LDL-C elevation (-74%, p < 0.001) than in subjects with isolated hypercholesterolemia (-53%, p 0.06). This study demonstrates that patients with Lp(a) elevation benefit most from LA treatment. Prospective trials to confirm these data are warranted. Copyright © 2017. Published by Elsevier B.V.

  9. The effect of an inhibitor of gut serotonin (LP533401) during the induction of periodontal disease.

    PubMed

    Lima, G M G; Corazza, B J M; Moraes, R M; de Oliveira, F E; de Oliveira, L D; Franco, G C N; Perrien, D S; Elefteriou, F; Anbinder, A L

    2016-10-01

    LP533401 is an inhibitor of tryptophan hydroxylase 1, which regulates serotonin production in the gut. Previous work indicates that LP533401 has an anabolic effect in bone. Thus, we hypothesized that inhibition of gut serotonin production may modulate the host response in periodontal disease. In this study, we aimed to analyze the effects of LP533401 in a rat periodontitis model to evaluate the role of gut serotonin in periodontitis pathophysiology. Twenty-four rats were divided into three groups: treated group (T: ligature-induced periodontal disease and LP533401, 25 mg/kg/d) by gavage; ligature group (L: ligature-induced periodontal disease only); and control group (C: without ligature-induced periodontal disease). After 28 d, radiographic alveolar bone support was measured on digital radiographs, and alveolar bone volume fraction, tissue mineral density and trabeculae characteristics were quantified by microcomputed tomography in the right hemi-mandible. Left hemi-mandibles were decalcified and alveolar bone loss, attachment loss and area of collagen in the gingiva were histologically analyzed. Significant difference between the L and C groups was found, confirming that periodontal disease was induced. We observed no difference between the T and L groups regarding alveolar bone destruction and area of collagen. LP533401 (25 mg/kg/d) for 28 d does not prevent bone loss and does not modulate host response in a rat model of induced periodontal disease. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. 78 FR 338 - Buckeye Hammond Railroad, L.L.C.; Acquisition and Operation Exemption; Buckeye Partners, L.P.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-03

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35697] Buckeye Hammond Railroad, L.L.C.; Acquisition and Operation Exemption; Buckeye Partners, L.P. Buckeye Hammond Railroad, L.L... acquire from Buckeye Partners, L.P., a noncarrier, and to operate approximately 6,797 feet (1.29 miles) of...

  11. 77 FR 11618 - Solutions Capital I, L.P.; Notice Seeking Exemption Under the Small Business Investment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-27

    ... SMALL BUSINESS ADMINISTRATION [License No. 03/03-0247] Solutions Capital I, L.P.; Notice Seeking Exemption Under the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Solutions Capital I, L.P., 1100 Wilson Blvd., Suite 3000, Arlington, VA 22209, a Federal Licensee under the...

  12. 78 FR 10128 - Expansion/Reorganization of Foreign-Trade Subzone 70T; Marathon Petroleum Company LP; Detroit, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-13

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Order No. 1881] Expansion/Reorganization of Foreign-Trade Subzone 70T; Marathon Petroleum Company LP; Detroit, MI Pursuant to its authority under the... Subzone 70T and remove Site 3 of the subzone at the Marathon Petroleum Company LP refinery in Detroit...

  13. Aerospace bibliography, seventh edition

    NASA Technical Reports Server (NTRS)

    Blashfield, J. F. (Compiler)

    1983-01-01

    Space travel, planetary probes, applications satellites, manned spaceflight, the impacts of space exploration, future space activities, astronomy, exobiology, aeronautics, energy, space and the humanities, and aerospace education are covered.

  14. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 16: A comparison of the technical communications practices of Russian and US aerospace engineers and scientists

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Kennedy, John M.; Barclay, Rebecca O.

    1993-01-01

    As part of Phase 4 of the NASA/DOD Aerospace Knowledge Diffusion Project, two studies were conducted that investigated the technical communications practices of Russian and U.S. aerospace engineers and scientists. Both studies have the same five objectives: first, to solicit the opinions of aerospace engineers and scientists regarding the importance of technical communications to their profession; second, to determine the use and production of technical communications by aerospace engineers and scientists; third, to seek their views about the appropriate content of an undergraduate course in technical communications; fourth, to determine aerospace engineers' and scientists' use of libraries, technical information centers, and on-line data bases; and fifth, to determine the use and importance of computer and information technology to them. A self-administered questionnaire was distributed to aerospace engineers and scientists at the Central Aero-Hydrodynamic Institute (TsAGI), NASA ARC, and NASA LaRC. The completion rates for the Russian and U.S. surveys were 64 and 61 percent, respectively. The responses of the Russian and U.S. participants, to selected questions, are presented in this report.

  15. NASA Deputy Administrator Tours Bigelow Aerospace

    NASA Image and Video Library

    2011-02-04

    Bigelow Aerospace President Robert Bigelow talks during a press conference shortly after he and NASA Deputy Administrator Lori Garver toured the Bigelow Aerospace facilities on Friday, Feb. 4, 2011, in Las Vegas. NASA has been discussing potential partnership opportunities with Bigelow for its inflatable habitat technologies as part of NASA's goal to develop innovative technologies to ensure that the U.S. remains competitive in future space endeavors. Photo Credit: (NASA/Bill Ingalls)

  16. 6. ROOF OF TURBINE BUILDING AND OF L.P. BOILER ROOM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. ROOF OF TURBINE BUILDING AND OF L.P. BOILER ROOM FROM NORTH END OF TURBINE BUILDING ROOF - Portland General Electric Company, Turbine Building, 1841 Southeast Water Street, Portland, Multnomah County, OR

  17. Aerospace Power Technology for Potential Terrestrial Applications

    NASA Technical Reports Server (NTRS)

    Lyons, Valerie J.

    2012-01-01

    Aerospace technology that is being developed for space and aeronautical applications has great potential for providing technical advances for terrestrial power systems. Some recent accomplishments arising from activities being pursued at the National Aeronautics and Space Administration (NASA) Centers is described in this paper. Possible terrestrial applications of the new aerospace technology are also discussed.

  18. NASA/DoD Aerospace Knowledge Diffusion Research Project. Report Number 14. Engineering Work and Information Use in Aerospace: Results of a Telephone Survey

    DTIC Science & Technology

    1992-10-01

    and superficial. The results of engineering information studies have not accumulated to form a significant body of knowledge that can be used to...Aerospace Kmowledge Diffits1ion. Studies indicate that timely access to STI can increase productivity and innovation and help aerospace engineers and...scientists maintain and improve their professional skills. These same studies demonstrate, however, how little is known about aerospace knowledge diffusion or

  19. Hormonal regulation of serum Lp (a) levels. Opposite effects after estrogen treatment and orchidectomy in males with prostatic carcinoma.

    PubMed Central

    Henriksson, P; Angelin, B; Berglund, L

    1992-01-01

    Serum concentrations of lipoprotein (a) [Lp (a)] were determined in two groups of elderly males suffering from prostatic carcinoma, who were randomized to treatment with estrogen (n = 15) or orchidectomy (n = 16). Estrogen was given as oral ethinylestradiol, 150 micrograms daily, combined with intramuscular polyestradiol phosphate, 80 mg/mo. The baseline levels were similar in both groups, but 6 mo after initiation of therapy, serum Lp (a) levels were decreased approximately 50% in the estrogen-treated group (P less than 0.001) in contrast to a 20% increase (P less than 0.01) in the orchidectomized group. Concomitantly, LDL cholesterol decreased by 30% and HDL cholesterol increased by almost 60% in the estrogen-treated patients. There was no relationship between the change in LDL cholesterol and Lp (a) reduction. In conclusion, Lp (a) levels in males were found to drastically decrease upon estrogen treatment and to increase after orchidectomy, suggesting that sex hormones, and particularly estrogens, exert a regulatory role on the serum Lp (a) level in man. Images PMID:1532586

  20. NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 23: The communications practices of US aerospace engineering faculty and students: Results of the phase 3 survey

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.

    1994-01-01

    The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis U.S. aerospace engineering faculty and students.

  1. 76 FR 36937 - Aerospace Safety Advisory Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-23

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-055)] Aerospace Safety Advisory Panel; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of meeting. SUMMARY... Aeronautics and Space Administration announce a forthcoming meeting of the Aerospace Safety Advisory Panel...

  2. 77 FR 1955 - Aerospace Safety Advisory Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-12

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 12-001] Aerospace Safety Advisory Panel; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of meeting. SUMMARY... Aeronautics and Space Administration announce a forthcoming meeting of the Aerospace Safety Advisory Panel...

  3. 78 FR 36793 - Aerospace Safety Advisory Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-19

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 13-068] Aerospace Safety Advisory Panel; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of meeting. SUMMARY... Aeronautics and Space Administration announce a forthcoming meeting of the Aerospace Safety Advisory Panel...

  4. 75 FR 36697 - Aerospace Safety Advisory Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (10-071)] Aerospace Safety Advisory Panel; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of meeting. SUMMARY... Aeronautics and Space Administration announce a forthcoming meeting of the Aerospace Safety Advisory Panel...

  5. 77 FR 25502 - Aerospace Safety Advisory Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-30

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (12-030)] Aerospace Safety Advisory Panel; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of meeting. SUMMARY... Aeronautics and Space Administration announce a forthcoming meeting of the Aerospace Safety Advisory Panel...

  6. 75 FR 6407 - Aerospace Safety Advisory Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (10- 020)] Aerospace Safety Advisory Panel; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of Meeting. SUMMARY... Aeronautics and Space Administration announce a forthcoming meeting of the Aerospace Safety Advisory Panel...

  7. 76 FR 2923 - Aerospace Safety Advisory Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-004)] Aerospace Safety Advisory Panel; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of Meeting. SUMMARY... Aeronautics and Space Administration announce a forthcoming meeting of the Aerospace Safety Advisory Panel...

  8. 75 FR 19662 - Aerospace Safety Advisory Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (10-043)] Aerospace Safety Advisory Panel; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of meeting. SUMMARY... Aeronautics and Space Administration announce a forthcoming meeting of the Aerospace Safety Advisory Panel...

  9. 75 FR 28547 - Aerospace Supplier Mission to Russia

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ... DEPARTMENT OF COMMERCE International Trade Administration Aerospace Supplier Mission to Russia...-users in Russia's aerospace market. Participating U.S. companies will receive market intelligence briefings by Russian industry experts, information on how to do business in Russia, networking opportunities...

  10. 76 FR 18210 - Texas Eastern Transmission, LP; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. CP11-138-000] Texas Eastern Transmission, LP; Notice of Application On March 15, 2011, Texas Eastern Transmission Corporation (Texas Eastern), 5400 Westheimer Court, Houston, Texas 77056-5310, filed with the Federal Energy Regulatory...

  11. 77 FR 33716 - Foreign-Trade Zone 70-Detroit, MI; Expansion of Subzone; Marathon Petroleum Company LP, (Oil...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-07

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [B-42-2012] Foreign-Trade Zone 70--Detroit, MI; Expansion of Subzone; Marathon Petroleum Company LP, (Oil Refinery) Detroit, MI An application has been...., grantee of FTZ 70, requesting an expansion of Subzone 70T, on behalf of Marathon Petroleum Company LP in...

  12. Prenatal exposure to a maternal LP diet decreases BDNF expression in the brains of the neonatal offspring

    USDA-ARS?s Scientific Manuscript database

    Maternal low protein (LP) diets during gestation cause learning and mernmy impai1ment as well as cognitive deficits in the neonatal and adult offsp1ing. The cellular and molecular mechanism that mediate the deleterious effects of prenatal exposure to a maternal LP diet on cognitive function is egreg...

  13. 1998 IEEE Aerospace Conference. Proceedings.

    NASA Astrophysics Data System (ADS)

    The following topics were covered: science frontiers and aerospace; flight systems technologies; spacecraft attitude determination and control; space power systems; smart structures and dynamics; military avionics; electronic packaging; MEMS; hyperspectral remote sensing for GVP; space laser technology; pointing, control, tracking and stabilization technologies; payload support technologies; protection technologies; 21st century space mission management and design; aircraft flight testing; aerospace test and evaluation; small satellites and enabling technologies; systems design optimisation; advanced launch vehicles; GPS applications and technologies; antennas and radar; software and systems engineering; scalable systems; communications; target tracking applications; remote sensing; advanced sensors; and optoelectronics.

  14. 78 FR 32294 - Escalate Capital Partners SBIC I, L.P., License No. 06/06-0335; Notice Seeking Exemption Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    ..., L.P. proposes to provide loan financing to SailPoint Technologies, Inc., 6034 West Courtyard Drive... Associate of Escalate Capital Partners, SBIC I, L.P., owns more than ten percent of SailPoint Technologies...

  15. NASA Aerospace Flight Battery Program: Recommendations for Technical Requirements for Inclusion in Aerospace Battery Procurements. Volume 2/Part 2

    NASA Technical Reports Server (NTRS)

    Jung, David S.; Manzo, Michelle A.

    2010-01-01

    This NASA Aerospace Flight Battery Systems Working Group was chartered within the NASA Engineering and Safety Center (NESC). The Battery Working Group was tasked to complete tasks and to propose proactive work to address battery related, agency-wide issues on an annual basis. In its first year of operation, this proactive program addressed various aspects of the validation and verification of aerospace battery systems for NASA missions. Studies were performed, issues were discussed and in many cases, test programs were executed to generate recommendations and guidelines to reduce risk associated with various aspects of implementing battery technology in the aerospace industry. This document contains Part 2 - Volume II Appendix A to Part 2 - Volume I.

  16. Advanced Materials and Coatings for Aerospace Applications

    NASA Technical Reports Server (NTRS)

    Miyoshi, Kazuhisa

    2004-01-01

    In the application area of aerospace tribology, researchers and developers must guarantee the highest degree of reliability for materials, components, and systems. Even a small tribological failure can lead to catastrophic results. The absence of the required knowledge of tribology, as Professor H.P. Jost has said, can act as a severe brake in aerospace vehicle systems-and indeed has already done so. Materials and coatings must be able to withstand the aerospace environments that they encounter, such as vacuum terrestrial, ascent, and descent environments; be resistant to the degrading effects of air, water vapor, sand, foreign substances, and radiation during a lengthy service; be able to withstand the loads, stresses, and temperatures encountered form acceleration and vibration during operation; and be able to support reliable tribological operations in harsh environments throughout the mission of the vehicle. This presentation id divided into two sections: surface properties and technology practice related to aerospace tribology. The first section is concerned with the fundamental properties of the surfaces of solid-film lubricants and related materials and coatings, including carbon nanotubes. The second is devoted to applications. Case studies are used to review some aspects of real problems related to aerospace systems to help engineers and scientists to understand the tribological issues and failures. The nature of each problem is analyzed, and the tribological properties are examined. All the fundamental studies and case studies were conducted at the NASA Glenn Research Center.

  17. Crew factors in the aerospace workplace

    NASA Technical Reports Server (NTRS)

    Kanki, Barbara G.; Foushee, H. C.

    1990-01-01

    The effects of technological change in the aerospace workplace on pilot performance are discussed. Attention is given to individual and physiological problems, crew and interpersonal problems, environmental and task problems, organization and management problems, training and intervention problems. A philosophy and conceptual framework for conducting research on these problems are presented and two aerospace studies are examined which investigated: (1) the effect of leader personality on crew effectiveness and (2) the working undersea habitat known as Aquarius.

  18. The 1999 NASA Aerospace Battery Workshop

    NASA Technical Reports Server (NTRS)

    Brewer, J. C. (Compiler)

    2000-01-01

    This document contains the proceedings of the 32nd annual NASA Aerospace Battery Workshop, hosted by the Marshall Space Flight Center on November 16-18, 1999. The workshop was attended by scientists and engineers from various agencies of the US Government, aerospace contractors, and battery manufacturers, as well as international participation in like kind from a number of countries around the world. The subjects covered included nickel-hydrogen, nickel-cadmium, lithium-ion, and silver-zinc technologies.

  19. The 2000 NASA Aerospace Battery Workshop

    NASA Technical Reports Server (NTRS)

    Brewer, J. C. (Compiler)

    2001-01-01

    This document contains the proceedings of the 33nd annual NASA Aerospace Battery Workshop, hosted by the Marshall Space Flight Center on November 14-16, 2000. The workshop was attended by scientists and engineers from various agencies of the U.S. Government, aerospace contractors, and battery manufacturers, as well as international participation in like kind from a number of countries around the world. The subjects covered included nickel-hydrogen, lithium-ion, lithium-sulfur, and silver-zinc technologies.

  20. Heart-Lung Interactions in Aerospace Medicine

    NASA Technical Reports Server (NTRS)

    Guy, Harold J. B.; Prisk, Gordon Kim

    1991-01-01

    Few of the heart-lung interactions that are discussed have been studied in any detail in the aerospace environment, but is seems that many such interactions must occur in the setting of altered accelerative loadings and pressure breathing. That few investigations are in progress suggests that clinical and academic laboratory investigators and aerospace organizations are further apart than during the pioneering work on pressure breathing and acceleration tolerance in the 1940s. The purpose is to reintroduce some of the perennial problems of aviation physiology as well as some newer aerospace concerns that may be of interest. Many possible heart-lung interactions are pondered, by necessity often drawing on data from within the aviation field, collected before the modern understanding of these interactions developed, or on recent laboratory data that may not be strictly applicable. In the field of zero-gravity effects, speculation inevitably outruns the sparse available data.

  1. Synthesis of a model trisaccharide for studying the interplay between the anti α-Gal antibody and the trans-sialidase reactions in Trypanosoma cruzi.

    PubMed

    Giorgi, M Eugenia; Lopez, Rosana; Agusti, Rosalia; Marino, Carla; de Lederkremer, Rosa M

    2017-10-10

    Trypanosoma cruzi, the etiologic agent of Chagas disease, is covered by a dense glycocalix mainly composed by glycoproteins called mucins which are also the acceptors of sialic acid in a reaction catalyzed by a trans-sialidase (TcTS). Sialylation of trypomastigote mucins protects the parasite from lysis by the anti α-Galp antibodies from serum. The TcTS is essential for the infection process since T. cruzi is unable to biosynthesize sialic acid. The enzyme specifically transfers it from a terminal β-d-Galp unit in the host glycoconjugate to terminal β-d-Galp units in the parasite mucins to construct the d-NeuNAc(α2→3)β-d-Galp motif. On the other hand, although galactose is the most abundant sugar in mucins of both, the infective trypomastigotes and the insect stage epimastigotes, α-d-Galp is only present in the infective stage whereas β-d-Galf is characteristic of the epimastigote stage of the less virulent strains. Neither α-d-Galp nor d-Galf is acceptor of sialic acid. In the mucins, some of the oligosaccharides are branched with terminal β-d-Galp units to be able to accept sialic acid in the TcTS reaction. Based on previous reports showing that anti α-Galp antibodies only partially colocalize with sialic acid, we have undertaken the synthesis of the trisaccharide α-d-Galp(1→3)-[β-d-Galp(1→6)]-d-Galp, the smallest structure containing both, the antigenic d-Galp(α1→3)-d-Galp unit and the sialic acid-acceptor β-d-Galp unit. The trisaccharide was obtained as the 6-aminohexyl glycoside to facilitate further conjugation for biochemical studies. The synthetic approach involved the α-galactosylation at O-4 of a suitable precursor of the reducing end, followed by β-galactosylation at O-6 of the same precursor and introduction of the 6-aminohexyl aglycone. The fully deprotected trisaccharide was successfully sialylated by TcTS using either 3'-sialyllactose or fetuin as donors. The product, 6-aminohexyl α-d-NeuNAc(2→3)-β-d-Galp(1→6)-[α-d-Galp

  2. Ethernet for Aerospace Applications - Ethernet Heads for the Skies

    NASA Technical Reports Server (NTRS)

    Grams, Paul R.

    2015-01-01

    One of the goals of aerospace applications is to reduce the cost and complexity of avionic systems. Ethernet is a highly scalable, flexible, and popular protocol. The aerospace market is large, with a forecasted production of over 50,000 turbine-powered aircraft valued at $1.7 trillion between 2012 and 2022. Boeing estimates demand for commercial aircraft by 2033 to total over 36,000 with a value of over $5 trillion. In 2014 US airlines served over 750 million passengers and this is growing over 2% yearly. Electronic fly-by-wire is now used for all airliners and high performance aircraft. Although Ethernet has been widely used for four decades, its use in aerospace applications is just beginning to become common. Ethernet is the universal solution in commercial networks because of its high bandwidths, lower cost, openness, reliability, maintainability, flexibility, and interoperability. However, when Ethernet was designed applications with time-critical, safety relevant and deterministic requirements were not given much consideration. Many aerospace applications use a variety of communication architectures that add cost and complexity. Some of them are SpaceWire, MIL-STD-1553, Avionics Full Duplex Switched Ethernet (AFDX), and Time-Triggered Ethernet (TTE). Aerospace network designers desire to decrease the number of networks to reduce cost and effort while improving scalability, flexibility, openness, maintainability, and reliability. AFDX and TTE are being considered more for critical aerospace systems because they provide redundancy, failover protection, guaranteed timing, and frame priority and are based on Ethernet IEEE 802.3. This paper explores the use of AFDX and TTE for aerospace applications.

  3. 78 FR 77618 - Airworthiness Directives; M7 Aerospace LLC Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ...-1057; Directorate Identifier 2013-CE-041-AD] RIN 2120-AA64 Airworthiness Directives; M7 Aerospace LLC...). SUMMARY: We propose to adopt a new airworthiness directive (AD) for all M7 Aerospace LLC Models SA226-AT... bulkhead. This proposed AD also requires reporting certain inspection results to M7 Aerospace LLC. We are...

  4. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 33: Technical communications practices and the use of information technologies as reported by Dutch and US aerospace engineers

    NASA Technical Reports Server (NTRS)

    Barclay, Rebecca O.; Pinelli, Thomas E.; Tan, Axel S. T.; Kennedy, John M.

    1993-01-01

    As part of Phase 4 of the NASA/DOD Aerospace Knowledge Diffusion Research Project, two studies were conducted that investigated the technical communications practices of Dutch and U.S. aerospace engineers and scientists. A self-administered questionnaire was distributed to aerospace engineers and scientists at the National Aerospace Laboratory (The Netherlands), and NASA ARC (U.S.), and NASA LaRC (U.S.). This paper presents responses of the Dutch and U.S. participants to selected questions concerning four of the seven project objectives: determining the importance of technical communications to aerospace engineering professionals, investigating the production of technical communications, examining the use and importance of computer and information technology, and exploring the use of electronic networks.

  5. Federal R and D Reductions, Market Share, and Aerospace Information Usage

    NASA Technical Reports Server (NTRS)

    Rocker, JoAnne; Roncaglia, George

    2000-01-01

    Reductions in federally funded research have a rippling effect over the entire aerospace industry. The decline in federal R&D spending in aerospace in recent years coincides with declines in U.S. aerospace market share, One of the lesser-understood factors in the declining U.S. market share may be the differing ways and intensity with which the U.S. and its competitors approach another trend, the increasing availability of large amounts of aerospace research information on the World Wide Web. The U.S. has been a pioneer in making research information available in electronic form, and the international community has long been a heavy consumer of that information. In essence, the U.S. contributes to the research efforts of its competitors, thus contributing to foreign aerospace consortiums efforts to gain market share in the aerospace industry, This may be a cautionary note to the U.S. aerospace industry to consider the use of R&D output in its own development and strategy because the foreign competition is using the U.S. scientific and technical literature.

  6. 78 FR 4842 - Linden VFT, LLC v. Brookfield Energy Marketing, LP, Cargill Power Markets, LLC; Notice of Complaint

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-23

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL13-40-000] Linden VFT, LLC v. Brookfield Energy Marketing, LP, Cargill Power Markets, LLC; Notice of Complaint Take notice that... Brookfield Energy Marketing, LP and Cargill Power Markets, LLC (Respondents) alleging that, Respondents...

  7. NASA/DoD Aerospace Knowledge Diffusion Research Project, Paper Six: Aerospace Knowledge Diffusion in the Academic Community: A Report of Phase 3 Activities of the NASA/DoD Aerospace Knowledge Diffusion Research Project

    DTIC Science & Technology

    1990-06-27

    empirically derived data, very little is known about the diffusion of knowledge in the aerospace industry both in terms of the channels used to communicate... diffusion of knowledge resulting from federally funded aerospace R&D and the academic community. Faced with shrinking enrollments, particularly at the

  8. Silicon Carbide Technologies for Lightweighted Aerospace Mirrors

    DTIC Science & Technology

    2008-09-01

    Silicon Carbide Technologies for Lightweighted Aerospace Mirrors Lawrence E. Matson (1) Ming Y. Chen (1) Brett deBlonk (2) Iwona A...glass and beryllium to produce lightweighted aerospace mirror systems has reached its limits due to the long lead times, high processing costs...for making mirror structural substrates, figuring and finishing technologies being investigated to reduce cost time and cost, and non-destructive

  9. An International Aerospace Information System: A Cooperative Opportunity.

    ERIC Educational Resources Information Center

    Blados, Walter R.; Cotter, Gladys A.

    1992-01-01

    Introduces and discusses ideas and issues relevant to the international unification of scientific and technical information (STI) through development of an international aerospace database (IAD). Specific recommendations for improving the National Aeronautics and Space Administration Aerospace Database (NAD) and for implementing IAD are given.…

  10. NSWC Crane Aerospace Cell Test History Database

    NASA Technical Reports Server (NTRS)

    Brown, Harry; Moore, Bruce

    1994-01-01

    The Aerospace Cell Test History Database was developed to provide project engineers and scientists ready access to the data obtained from testing of aerospace cell designs at Naval Surface Warfare Center, Crane Division. The database is intended for use by all aerospace engineers and scientists involved in the design of power systems for satellites. Specifically, the database will provide a tool for project engineers to review the progress of their test at Crane and to have ready access to data for evaluation. Additionally, the database will provide a history of test results that designers can draw upon to answer questions about cell performance under certain test conditions and aid in selection of a cell for a satellite battery. Viewgraphs are included.

  11. Adopting exergy analysis for use in aerospace

    NASA Astrophysics Data System (ADS)

    Hayes, David; Lone, Mudassir; Whidborne, James F.; Camberos, José; Coetzee, Etienne

    2017-08-01

    Thermodynamic analysis methods, based on an exergy metric, have been developed to improve system efficiency of traditional heat driven systems such as ground based power plants and aircraft propulsion systems. However, in more recent years interest in the topic has broadened to include applying these second law methods to the field of aerodynamics and complete aerospace vehicles. Work to date is based on highly simplified structures, but such a method could be shown to have benefit to the highly conservative and risk averse commercial aerospace sector. This review justifies how thermodynamic exergy analysis has the potential to facilitate a breakthrough in the optimization of aerospace vehicles based on a system of energy systems, through studying the exergy-based multidisciplinary design of future flight vehicles.

  12. Improving Attitudes and Practices in Teaching/Learning by Means of Aerospace In-Service Teacher Education. Aerospace Teacher Education Statistical Study.

    ERIC Educational Resources Information Center

    Romero, J. Christian

    The purpose of this investigation was to examine the relationship of the first two aerospace education workshops conducted by the United States Space Foundation and sponsored by the Univesity of Colorado, Colorado Springs, and the United States Air Force Academy to attitudes and practices of workshop participants regarding aerospace education. To…

  13. Challenges for Insertion of Structural Nanomaterials in Aerospace Applications

    NASA Technical Reports Server (NTRS)

    Sochi, Emilie J.

    2012-01-01

    In the two decades since Iijima's report on carbon nanotubes (CNT), there has been great interest in realizing the benefits of mechanical properties observed at the nanoscale in large-scale structures. The weight savings possible due to dramatic improvements in mechanical properties relative to state-of-the-art material systems can be game changing for applications like aerospace vehicles. While there has been significant progress in commercial production of CNTs, major aerospace applications that take advantage of properties offered by this material have yet to be realized. This paper provides a perspective on the technical challenges and barriers for insertion of CNTs as an emerging material technology in aerospace applications and proposes approaches that may reduce the typical timeframe for technology maturation and insertion into aerospace structures.

  14. 77 FR 12867 - Accreditation of Saybolt LP, as a Commercial Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... given that, pursuant to 19 CFR 151.12, Saybolt LP, 109 Woodland Dr., Laplace, LA 70068, has been... Pennsylvania Avenue NW., Suite 1500N, Washington, DC 20229, 202-344- 1060. Dated: February 22, 2012. Ira S...

  15. NASA Deputy Administrator Tours Bigelow Aerospace

    NASA Image and Video Library

    2011-02-04

    NASA Deputy Administrator Lori Garver views the inside of a full scale mockup of Bigelow Aerospace's Space Station Alpha during a tour of the Bigelow Aerospace facilities by the company's President Robert Bigelow on Friday, Feb. 4, 2011, in Las Vegas. NASA has been discussing potential partnership opportunities with Bigelow for its inflatable habitat technologies as part of NASA's goal to develop innovative technologies to ensure that the U.S. remains competitive in future space endeavors. Photo Credit: (NASA/Bill Ingalls)

  16. Novel Wiring Technologies for Aerospace Applications

    NASA Technical Reports Server (NTRS)

    Gibson, Tracy L.; Parrish, Lewis M.

    2014-01-01

    Because wire failure in aerospace vehicles could be catastrophic, smart wiring capabilities have been critical for NASA. Through the years, researchers at Kennedy Space Center (KSC) have developed technologies, expertise, and research facilities to meet this need. In addition to aerospace applications, NASA has applied its knowledge of smart wiring, including self-healing materials, to serve the aviation industry. This webinar will discuss the development efforts of several wiring technologies at KSC and provide insight into both current and future research objectives.

  17. NASA Ames aerospace systems directorate research

    NASA Technical Reports Server (NTRS)

    Albers, James A.

    1991-01-01

    The Aerospace Systems Directorate is one of four research directorates at the NASA Ames Research Center. The Directorate conducts research and technology development for advanced aircraft and aircraft systems in intelligent computational systems and human-machine systems for aeronautics and space. The Directorate manages research and aircraft technology development projects, and operates and maintains major wind tunnels and flight simulation facilities. The Aerospace Systems Directorate's research and technology as it relates to NASA agency goals and specific strategic thrusts are discussed.

  18. 75 FR 32230 - Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-07

    ... SMALL BUSINESS ADMINISTRATION [License No. 09/79-0454] Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Emergence Capital Partners SBIC, L.P., 160 Bovet Road, Suite 300, San Mateo...

  19. 76 FR 25732 - Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-05

    ... SMALL BUSINESS ADMINISTRATION [License No. 09/79-0454] Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Emergence Capital Partners SBIC, L.P., 160 Bovet Road, Suite 300, San Mateo...

  20. 78 FR 62931 - Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-22

    ... SMALL BUSINESS ADMINISTRATION [License No. 09/79-0454] Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Emergence Capital Partners SBIC, L.P., 160 Bovet Road, Suite 300, San Mateo...

  1. 77 FR 14853 - Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ... SMALL BUSINESS ADMINISTRATION [License No. 09/79-0454] Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Emergence Capital Partners SBIC, L.P., 160 Bovet Road, Suite 300, San Mateo...

  2. 76 FR 9630 - Convergent Capital Partners II, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-18

    ... SMALL BUSINESS ADMINISTRATION [License No. 05/05-0293] Convergent Capital Partners II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Convergent Capital Partners II, L.P., 505 North Highway 169, Suite 245...

  3. 76 FR 74115 - Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-30

    ... SMALL BUSINESS ADMINISTRATION [License No. 09/79-0454] Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Emergence Capital Partners SBIC, L.P., 160 Bovet Road, Suite 300, San Mateo...

  4. 76 FR 21936 - Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-19

    ... SMALL BUSINESS ADMINISTRATION [License No. 09/79-0454] Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Emergence Capital Partners SBIC, L.P., 160 Bovet Road, Suite 300, San Mateo...

  5. 75 FR 54661 - Main Street Mezzanine Fund, LP; Notice of Exemption Under Section 312 of the Small Business...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... SMALL BUSINESS ADMINISTRATION [License No. 06/06-0326] Main Street Mezzanine Fund, LP; Notice of Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby...), Financings which Constitute Conflicts of Interest. Main Street Mezzanine Fund, LP provided a debt/equity...

  6. 76 FR 44899 - Astoria Generating Company, L.P and TC Ravenswood, LLC v. New York Independent System Operator...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-27

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL11-50-000] Astoria Generating Company, L.P and TC Ravenswood, LLC v. New York Independent System Operator, Inc.; Notice of... (Commission), Astoria Generating Company, L.P. and TC Ravenswood, LLC (Complainants) filed a formal complaint...

  7. 78 FR 49753 - Granting of Request for Early Termination of the Waiting Period Under the Premerger Notification...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-15

    ... Power Fund V (FT), L.P. 20131078 G Marathon Petroleum Corporation; The Andersons Clymers Ethanol LLC; Marathon Petroleum Corporation. 20131080 G Precision Castparts Corp.; Exacta Aerospace, Inc.; Precision...

  8. Cost-effective lightweight mirrors for aerospace and defense

    NASA Astrophysics Data System (ADS)

    Woodard, Kenneth S.; Comstock, Lovell E.; Wamboldt, Leonard; Roy, Brian P.

    2015-05-01

    The demand for high performance, lightweight mirrors was historically driven by aerospace and defense (A&D) but now we are also seeing similar requirements for commercial applications. These applications range from aerospace-like platforms such as small unmanned aircraft for agricultural, mineral and pollutant aerial mapping to an eye tracking gimbaled mirror for optometry offices. While aerospace and defense businesses can often justify the high cost of exotic, low density materials, commercial products rarely can. Also, to obtain high performance with low overall optical system weight, aspheric surfaces are often prescribed. This may drive the manufacturing process to diamond machining thus requiring the reflective side of the mirror to be a diamond machinable material. This paper summarizes the diamond machined finishing and coating of some high performance, lightweight designs using non-exotic substrates to achieve cost effective mirrors. The results indicate that these processes can meet typical aerospace and defense requirements but may also be competitive in some commercial applications.

  9. 77 FR 50145 - Approval of Saybolt LP, as a Commercial Gauger

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-20

    ... 19 CFR 151.13, Saybolt LP, 120 West Highway 30, Gonzales, LA 70737, has been approved to gauge... Pennsylvania Avenue NW., Suite 1500N, Washington, DC 20229, 202-344- 1060. Dated: August 13, 2012. Ira S. Reese...

  10. 77 FR 47430 - Approval of Saybolt LP, as a Commercial Gauger

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-08

    ... 19 CFR 151.13, Saybolt LP, 4025 Oak Lane, Sulfur, LA 70665, has been approved to gauge petroleum... Pennsylvania Avenue NW., Suite 1500N, Washington, DC 20229, 202-344- 1060. Dated: July 26, 2012. Ira S. Reese...

  11. Combustion Processes in the Aerospace Environment

    NASA Technical Reports Server (NTRS)

    Huggett, Clayton

    1969-01-01

    The aerospace environment introduces new and enhanced fire hazards because the special atmosphere employed may increase the frequency and intensity of fires, because the confinement associated with aerospace systems adversely affects the dynamics of fire development and control, and because the hostile external environments limit fire control and rescue operations. Oxygen enriched atmospheres contribute to the fire hazard in aerospace systems by extending the list of combustible fuels, increasing the probability of ignition, and increasing the rates of fire spread and energy release. A system for classifying atmospheres according to the degree of fire hazard, based on the heat capacity of the atmosphere per mole of oxygen, is suggested. A brief exploration of the dynamics of chamber fires shows that such fires will exhibit an exponential growth rate and may grow to dangerous size in a very short time. Relatively small quantities of fuel and oxygen can produce a catastrophic fire in a closed chamber.

  12. CNT-based Thermal Interface Materials for Load-Bearing Aerospace Applications

    DTIC Science & Technology

    2012-08-01

    CNT -based Thermal Interface Materials for Load-Bearing Aerospace Applications Michael Bifano, Pankaj Kaul and Vikas Prakash (PI) Department...4. TITLE AND SUBTITLE CNT -based Thermal Interface Materials for Load-Bearing Aerospace Applications 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...Z39-18 Objective Develop multifunctional CNT -epoxy Thermal Interface Materials (TIMs) for load bearing aerospace applications. Emphasis - To

  13. Women, Innovation and Aerospace Event

    NASA Image and Video Library

    2012-03-08

    Catherine Didion, far right, Senior Fellow, National Academy of Engineering, participates in a panel discussion at the Women, Innovation and Aerospace event celebrating Women's History Month at the George Washington University Jack Morton Auditorium, Thursday, March 8, 2012 in Washington. Didion is joined by Marcia Smith, President, Space Policy Online.com, and Veronica Villalobos, Director, Office of Diversity and Inclusion, Office of Personnel Management, far left. The WIA day-long event will help to foster a discussion for students and early career professionals about how to continue to encourage women to enter and succeed in the field of aerospace. Photo Credit: (NASA/Carla Cioffi)

  14. 75 FR 79065 - Emergence Capital Partners SBIC, L.P. License No. 09/79-0454; Notice Seeking Exemption Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... SMALL BUSINESS ADMINISTRATION Emergence Capital Partners SBIC, L.P. License No. 09/79-0454; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Emergence Capital Partners SBIC, L.P., 160 Bovet Road, Suite 300, San Mateo, CA 94402...

  15. 75 FR 54661 - Main Street Capital II, LP; Notice of Exemption Under Section 312 of the Small Business...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... SMALL BUSINESS ADMINISTRATION [License No. 06/06-0332] Main Street Capital II, LP; Notice of Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Main Street Capital II, LP, 1300 Post Oak Blvd, Suite 800, Houston, TX 77056, a Federal...

  16. 75 FR 32230 - Solutions Capital I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-07

    ... SMALL BUSINESS ADMINISTRATION [License No. 03/03-0247] Solutions Capital I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Solutions Capital I, L.P., 1100 Wilson Blvd., Suite 3000, Arlington, VA 22209, a Federal...

  17. 75 FR 22435 - Pharos Capital Partners II, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... SMALL BUSINESS ADMINISTRATION [License No. 06/76-0329] Pharos Capital Partners II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Pharos Capital Partners II, L.P., 1 Burton Hills Boulevard, Suite 180, Nashville, TN...

  18. 75 FR 3502 - KLH Capital, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment Act...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-21

    ... SMALL BUSINESS ADMINISTRATION [License No. 04/04-0296] KLH Capital, L.P.; Notice Seeking Exemption Under 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that KLH Capital, L.P., 101 East Kennedy Boulevard, Suite 3925, Tampa, Florida 33602, a Federal Licensee under the...

  19. 76 FR 76474 - Emergence Capital Partners SBIC, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ..., L.P. proposes to provide equity financing to Lithium Technologies, Inc., 6121 Hollis Street, Suite 4, Emeryville, CA 94608 (``Lithium''). The financing is contemplated for working capital and general operating... Partners SBIC, L.P., own more than ten percent of Lithium. Therefore, Lithium is considered an Associate of...

  20. 76 FR 76475 - Tregaron Opportunity Fund I, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-07

    ... SMALL BUSINESS ADMINISTRATION [License No. 09/09-0463] Tregaron Opportunity Fund I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Tregaron Opportunity Fund I, L.P., 540 University Avenue, Suite 250, Palo Alto, CA...

  1. 77 FR 12868 - Approval of Saybolt LP, as a Commercial Gauger

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... 19 CFR 151.13, Saybolt LP, 190 James Drive East, Suite 110, St. Rose, LA 70087, has been approved to... Avenue NW., Suite 1500N, Washington, DC 20229, 202-344- 1060. Dated: February 22, 2012. Ira S. Reese...

  2. 78 FR 9781 - Airworthiness Directives; Pacific Aerospace Limited Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-12

    ...: +64 7 843 6134; email: [email protected]nz ; Internet: http://www.aerospace.co.nz/ . You may...; email: [email protected]nz ; Internet: http://www.aerospace.co.nz/ . (4) You may view this service...

  3. Reciprocal relationship of T regulatory cells and monocytic myeloid-derived suppressor cells in LP-BM5 murine retrovirus-induced immunodeficiency.

    PubMed

    O'Connor, Megan A; Vella, Jennifer L; Green, William R

    2016-02-01

    Immunomodulatory cellular subsets, including myeloid-derived suppressor cells (MDSCs) and T regulatory cells (Tregs), contribute to the immunosuppressive tumour microenvironment and are targets of immunotherapy, but their role in retroviral-associated immunosuppression is less well understood. Due to known crosstalk between Tregs and MDSCs in the tumour microenvironment, and also their hypothesized involvement during human immunodeficiency virus/simian immunodeficiency virus infection, studying the interplay between these immune cells during LP-BM5 retrovirus-induced murine AIDS is of interest. IL-10-producing FoxP3+ Tregs expanded after LP-BM5 infection. Following in vivo adoptive transfer of natural Treg (nTreg)-depleted CD4+T-cells, and subsequent LP-BM5 retroviral infection, enriched monocytic MDSCs (M-MDSCs) from these nTreg-depleted mice displayed altered phenotypic subsets. In addition, M-MDSCs from LP-BM5-infected nTreg-depleted mice exhibited increased suppression of T-cell, but not B-cell, responses, compared with M-MDSCs derived from non-depleted LP-BM5-infected controls. Additionally, LP-BM5-induced M-MDSCs modulated the production of IL-10 by FoxP3+ Tregs in vitro. These collective data highlight in vitro and for the first time, to the best of our knowledge, in vivo reciprocal modulation between retroviral-induced M-MDSCs and Tregs, and may provide insight into the immunotherapeutic targeting of such regulatory cells during retroviral infection.

  4. Effect of over-the-counter fish-oil administration on plasma Lp(a) levels in an end-stage renal disease population.

    PubMed

    Beavers, Kristen M; Beavers, Daniel P; Bowden, Rodney G; Wilson, Ronald L; Gentile, Mindy

    2009-11-01

    This study sought to examine the effect of n-3 supplementation on lipoprotein(a) (Lp(a)) levels in end-stage renal disease (ESRD) patients undergoing chronic hemodialysis. The present study was conducted using a double-blind, permuted-randomized, controlled experimental protocol. This study took place at the Central Texas Nephrology Associates Dialysis Clinic (Waco, TX). Patients with ESRD and associated with the Central Texas Nephrology Associates who were undergoing chronic hemodialysis participated in this study. Patients with ESRD were followed prospectively while receiving supplements of fish oil (treatment, eicosapentaenoic acid, 0.96g/day, and docosahexaenoic acid, 0.6g/day) or corn oil (control subjects) for 6 months. After a 12-hour fast, participants donated 12mL of blood for analysis of Lp(a) at baseline and at 6 months. The comparison of Lp(a) concentration by group at 6 months was the primary outcome measure of the study. Our study suggests that fish-oil supplementation did not decrease levels of Lp(a) (P=.66), compared with control subjects. We failed to show a significant effect of 6 months of over-the-counter fish-oil supplementation on Lp(a) status in an ESRD population, although results from this study support findings from other studies suggesting that African Americans have higher Lp(a) concentrations than persons of Caucasian decent.

  5. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 40: Technical communications in aerospace education: A study of AIAA student members

    NASA Technical Reports Server (NTRS)

    Kennedy, John M.; Pinelli, Thomas E.; Barclay, Rebecca O.

    1994-01-01

    This paper describes the preliminary analysis of a survey of the American Institute of Aeronautics and Astronautics (AIAA) student members. In the paper we examine (1) the demographic characteristics of the students, (2) factors that affected their career decisions, (3) their career goals and aspirations, and (4) their training in technical communication and techniques for finding and using aerospace scientific and technical information (STI). We determine that aerospace engineering students receive training in technical communication skills and the use of STI. While those in the aerospace industry think that more training is needed, we believe the students receive the appropriate amount of training. We think that the differences between the amount of training students receive and the perception of training needs is related partially to the characteristics of the students and partially to the structure of the aerospace STI dissemination system. Overall, we conclude that the students' technical communication training and knowledge of STI, while limited by external forces, makes it difficult for students to achieve their career goals.

  6. High-Performing, Low-Temperature-Operating, Long-Lifetime Aerospace Lubricants

    NASA Technical Reports Server (NTRS)

    Joshi, Prakash

    2015-01-01

    Long-duration space exploration will require spacecraft systems that can operate effectively over several years with minimal or no maintenance. Aerospace lubricants are key components of spacecraft systems. Physical Sciences Inc., has synthesized and characterized novel ionic liquids for use in aerospace lubricants that contribute to decreased viscosity, friction, and wear in aerospace systems. The resulting formulations offer low vapor pressure and outgassing properties and thermal stability up to 250 C. They are effective for use at temperatures as low as -70 C and provide long-term operational stability in aerospace systems. In Phase II, the company scaled several new ionic liquids and evaluated a novel formulation in a NASA testbed. The resulting lubricant compounds will offer lower volatility, decreased corrosion, and better tribological characteristics than standard liquid lubricants, particularly at lower temperatures.

  7. Structures Technology for Future Aerospace Systems

    NASA Technical Reports Server (NTRS)

    Noor, Ahmed K.; Venneri, Samuel L.; Paul, Donald B.; Hopkins, Mark A.

    2000-01-01

    An overview of structures technology for future aerospace systems is given. Discussion focuses on developments in component technologies that will improve the vehicle performance, advance the technology exploitation process, and reduce system life-cycle costs. The component technologies described are smart materials and structures, multifunctional materials and structures, affordable composite structures, extreme environment structures, flexible load bearing structures, and computational methods and simulation-based design. The trends in each of the component technologies are discussed and the applicability of these technologies to future aerospace vehicles is described.

  8. The 1993 NASA Aerospace Battery Workshop

    NASA Technical Reports Server (NTRS)

    Brewer, Jeffrey C. (Compiler)

    1994-01-01

    This document contains the proceedings of the 26th annual NASA Aerospace Battery Workshop, hosted by the Marshall Space Flight Center on 16-18 Nov. 1993. The workshop was attended by scientists and engineers from various agencies of the U.S. Government, aerospace contractors, and battery manufacturers, as well as international participation in like kind from a number of countries around the world. The subjects covered included nickel-cadmium, nickel-hydrogen, nickel-metal hydride, and lithium based technologies, as well as advanced technologies including various bipolar designs.

  9. 78 FR 64933 - Texas Eastern Transmission, LP; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-30

    ... and necessity to construct its Emerald Longwall Mine Panel D1 Project. Texas Eastern states in its application that, due to anticipated longwall mining activities of Emerald Coal Resources, LP (Emerald) in Greene County, Pennsylvania in Panel D1 of Emerald's mine, ground subsidence may occur. In order to...

  10. Aerospace manpower transfer to small business enterprises

    NASA Technical Reports Server (NTRS)

    Green, M. K.

    1972-01-01

    The feasibility of a program to effect transfer of aerospace professional people from the ranks of the unemployed into gainful employment in the small business community was investigated. The effectiveness of accomplishing transfer of technology from the aerospace effort into the private sector through migration of people rather than products or hardware alone was also studied. Two basic methodologies were developed. One involves the matching of ex-aerospace professionals and small companies according to their mutual needs. A training and indoctrination program is aimed at familiarizing the professional with the small company environment, and a program of follow-up counseling is defined. The second methodology incorporates efforts to inform and arouse interest among the nonaerospace business community toward affirmative action programs that will serve mutual self-interests of the individuals, companies, and communities involved.

  11. 48 CFR 1852.244-70 - Geographic participation in the aerospace program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... in the aerospace program. 1852.244-70 Section 1852.244-70 Federal Acquisition Regulations System... CLAUSES Texts of Provisions and Clauses 1852.244-70 Geographic participation in the aerospace program. As prescribed in 1844.204-70, insert the following clause: Geographic Participation in the Aerospace Program...

  12. 48 CFR 1852.244-70 - Geographic participation in the aerospace program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... in the aerospace program. 1852.244-70 Section 1852.244-70 Federal Acquisition Regulations System... CLAUSES Texts of Provisions and Clauses 1852.244-70 Geographic participation in the aerospace program. As prescribed in 1844.204-70, insert the following clause: Geographic Participation in the Aerospace Program...

  13. 48 CFR 1852.244-70 - Geographic participation in the aerospace program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... in the aerospace program. 1852.244-70 Section 1852.244-70 Federal Acquisition Regulations System... CLAUSES Texts of Provisions and Clauses 1852.244-70 Geographic participation in the aerospace program. As prescribed in 1844.204-70, insert the following clause: Geographic Participation in the Aerospace Program...

  14. 48 CFR 1852.244-70 - Geographic participation in the aerospace program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... in the aerospace program. 1852.244-70 Section 1852.244-70 Federal Acquisition Regulations System... CLAUSES Texts of Provisions and Clauses 1852.244-70 Geographic participation in the aerospace program. As prescribed in 1844.204-70, insert the following clause: Geographic Participation in the Aerospace Program...

  15. 48 CFR 1852.244-70 - Geographic participation in the aerospace program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the aerospace program. 1852.244-70 Section 1852.244-70 Federal Acquisition Regulations System NATIONAL... Provisions and Clauses 1852.244-70 Geographic participation in the aerospace program. As prescribed in 1844.204-70, insert the following clause: Geographic Participation in the Aerospace Program (APR 1985) (a...

  16. PLA2G7 genotype, Lp-PLA2 activity and coronary heart disease risk in 10,494 cases and 15,624 controls of European ancestry

    PubMed Central

    Casas, Juan P.; Ninio, Ewa; Panayiotou, Andrie; Palmen, Jutta; Cooper, Jackie A; Ricketts, Sally L; Sofat, Reecha; Nicolaides, Andrew N; Corsetti, James P; Fowkes, F Gerry R; Tzoulaki, Ioanna; Kumari, Meena; Brunner, Eric J; Kivimaki, Mika; Marmot, Michael G; Hoffmann, Michael M; Winkler, Karl; März, Winfred; Ye, Shu; Stirnadel, Heide A; MBBChir, Kay-Tee Khaw; Humphries, Steve E; Sandhu, Manjinder S; Hingorani, Aroon D; Talmud, Philippa J

    2012-01-01

    Background Higher Lp-PLA2 activity is associated with increased risk of coronary heart disease (CHD), making Lp-PLA2 a potential therapeutic target. PLA2G7 variants associated with Lp-PLA2 activity could evaluate whether this relationship is causal. Methods and Results A meta-analysis including a total of 12 studies (5 prospective, 4 case-control, 1 case-only and 2 cross-sectional, n=26,118) was undertaken to examine the association of: (i) LpPLA2 activity vs. cardiovascular biomarkers and risk factors and CHD events (two prospective studies; n=4884); ii) PLA2G7 SNPs and Lp-PLA2 activity (3 prospective, 2 case-control, 2 cross-sectional studies; up to n=6094); and iii) PLA2G7 SNPs and angiographic coronary artery disease (2 case-control, 1 case-only study; n=4971 cases) and CHD events (5 prospective, 2 case-control studies; n=5523). Lp-PLA2 activity correlated with several CHD risk markers. Hazard ratio for CHD events top vs. bottom quartile of Lp-PLA2 activity was 1.61 (95%CI: 1.31, 1.99) and 1.17 (95%CI: 0.91, 1.51) after adjustment for baseline traits. Of seven SNPs, rs1051931 (A379V) showed the strongest association with Lp-PLA2 activity, VV subjects having 7.2% higher activity than AAs. Genotype was not associated with risk markers, angiographic coronary disease (OR 1.03 (95%CI 0.80, 1.32), or CHD events (OR 0.98 (95%CI 0.82, 1.17). Conclusions Unlike Lp-PLA2 activity, PLA2G7 variants associated with modest effects on Lp-PLA2 activity were not associated with cardiovascular risk markers, coronary atheroma or CHD. Larger association studies, identification of SNPs with larger effects, or randomised trials of specific Lp-PLA2 inhibitors are needed to confirm/refute a contributory role for Lp-PLA2 in CHD. PMID:20479152

  17. IS30-related transposon mediated insertional inactivation of bile salt hydrolase (bsh1) gene of Lactobacillus plantarum strain Lp20.

    PubMed

    Kumar, Rajesh; Grover, Sunita; Kaushik, Jai K; Batish, Virender Kumar

    2014-01-01

    Lactobacillus plantarum is a flexible and versatile microorganism that inhabits a variety of niches, and its genome may express up to four bsh genes to maximize its survival in the mammalian gut. However, the ecological significance of multiple bsh genes in L. plantarum is still not clearly understood. Hence, this study demonstrated the disruption of bile salt hydrolase (bsh1) gene due to the insertion of a transposable element in L. plantarum Lp20 - a wild strain of human fecal origin. Surprisingly, L. plantarum strain Lp20 produced a ∼2.0 kb bsh1 amplicon against the normal size (∼1.0 kb) bsh1 amplicon of Bsh(+)L. plantarum Lp21. Strain Lp20 exhibited minimal Bsh activity in spite of having intact bsh2, bsh3 and bsh4 genes in its genome and hence had a Bsh(-) phenotype. Cloning and sequence characterization of Lp20 bsh1 gene predicted four individual open reading frames (ORFs) within this region. BLAST analysis of ORF1 and ORF2 revealed significant sequence similarity to the L. plantarum bsh1 gene while ORF3 and ORF4 showed high sequence homology to IS30-family transposases. Since, IS30-related transposon element was inserted within Lp20 bsh1 gene in reverse orientation (3'-5'), it introduced several stop codons and disrupted the protein reading frames of both Bsh1 and transposase. Inverted terminal repeats (GGCAGATTG) of transposon, mediated its insertion at 255-263 nt and 1301-1309 nt positions of Lp20 bsh1 gene. In conclusion, insertion of IS30 related-transposon within the bsh1 gene sequence of L. plantarum strain Lp20 demolished the integrity and functionality of Bsh1 enzyme. Additionally, this transposon DNA sequence remains active among various Lactobacillus spp. and hence harbors the potential to be explored in the development of efficient insertion mutagenesis system. Copyright © 2013 Elsevier GmbH. All rights reserved.

  18. Emerging Needs for Pervasive Passive Wireless Sensor Networks on Aerospace Vehicles

    NASA Technical Reports Server (NTRS)

    Wilson, William C.; Juarez, Peter D.

    2014-01-01

    NASA is investigating passive wireless sensor technology to reduce instrumentation mass and volume in ground testing, air flight, and space exploration applications. Vehicle health monitoring systems (VHMS) are desired on all aerospace programs to ensure the safety of the crew and the vehicles. Pervasive passive wireless sensor networks facilitate VHMS on aerospace vehicles. Future wireless sensor networks on board aerospace vehicles will be heterogeneous and will require active and passive network systems. Since much has been published on active wireless sensor networks, this work will focus on the need for passive wireless sensor networks on aerospace vehicles. Several passive wireless technologies such as microelectromechanical systems MEMS, SAW, backscatter, and chipless RFID techniques, have all shown potential to meet the pervasive sensing needs for aerospace VHMS applications. A SAW VHMS application will be presented. In addition, application areas including ground testing, hypersonic aircraft and spacecraft will be explored along with some of the harsh environments found in aerospace applications.

  19. NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 29: A comparison of the technical communications practices of Japanese and US aerospace engineers and scientists

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.

    1994-01-01

    As part of Phase 4 of the NASA/DoD Aerospace Knowledge Diffusion Research Project, two studies were conducted that investigated the technical communications practices of Japanese and U.S. aerospace engineers and scientists. Both studies have the same seven objectives: first, to solicit the opinions of aerospace engineers and scientists regarding the importance of technical communications to their profession; second, to determine the use and production of technical communications by aerospace engineers and scientists; third; to seek their views about the appropriate content of an undergraduate course in technical communications; fourth, to determine aerospace engineers' and scientists' use of libraries, technical information centers, and on-line data bases; fifth, to determine the use and importance of computer and information technology to them; sixth, to determine their use of electronic networks; and seventh, to determine their use of foreign and domestically produced technical reports. A self-administered questionnaire was distributed to aerospace engineers and scientists in Japan and at the NASA Ames Research Center and the NASA Langley Research Center. The completion rates for the Japanese and U.S. surveys were 85 and 61 percent, respectively. Responses of the Japanese and U.S. participants to selected questions are presented in this report.

  20. A RESOURCE BOOK OF AEROSPACE ACTIVITIES, K-6.

    ERIC Educational Resources Information Center

    Lincoln Public Schools, NE.

    THIS RESOURCE BOOK OF ACTIVITIES WAS WRITTEN FOR TEACHERS OF GRADES K-6, TO HELP THEM INTEGRATE AEROSPACE SCIENCE WITH THE REGULAR LEARNING EXPERIENCES OF THE CLASSROOM. SUGGESTIONS ARE MADE FOR INTRODUCING AEROSPACE CONCEPTS INTO THE VARIOUS SUBJECT FIELDS SUCH AS LANGUAGE ARTS, MATHEMATICS, PHYSICAL EDUCATION, SOCIAL STUDIES, AND OTHERS. SUBJECT…

  1. Current Trends in Aerospace Engineering Education on Taiwan.

    ERIC Educational Resources Information Center

    Hsieh, Sheng-Jii

    A proposal for current trends in Aerospace Engineering Education on Taiwan has been drawn from the suggestions made after a national conference of "Workshop on Aerospace Engineering Education Reform." This workshop was held in January 18-20, 1998, at the Institute of Aeronautics and Astronautics, National Cheng Kung University, Tainan,…

  2. 76 FR 77580 - Contemporary Healthcare Senior Lien Fund I, LP; Notice Seeking Exemption Under Section 312 of the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-13

    ... SMALL BUSINESS ADMINISTRATION [License No. 02/02-0649] Contemporary Healthcare Senior Lien Fund I... Interest Notice is hereby given that Contemporary Healthcare Senior Lien Fund I, LP, 1040 Broad Street... Senior Lien Fund I, LP, proposes to provide a loan to New Port Richey Real Estate, LLC, and New Port...

  3. 75 FR 28657 - Dell Products LP-Parmer North Location, a Subsidiary of Dell, Inc., Including On-Site Leased...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ... Spherion Corporation; Round Rock, TX; Dell Products LP--Parmer North One; Austin, TX; Amended Certification... Products LP--Parmer North Location, a Subsidiary of Dell, Inc., Including On-Site Leased Workers From... Act of 1974, as amended (``Act''), 19 U.S.C. 2273, the Department of Labor issued a Certification of...

  4. Development of first generation aerospace NiMH cells

    NASA Technical Reports Server (NTRS)

    Tinker, Lawrence; Dell, Dan; Wu, Tony; Rampel, Guy

    1993-01-01

    Gates Aerospace Batteries in conjunction with Gates Energy Products (GEP) has been developing NiMH technology for aerospace use since 1990. GEP undertook the development of NiMH technology for commercial cell applications in 1987. This program focused on wound cell technology for replacement of current NiCd technology. As an off shoot of this program small, wound cells were used to evaluate initial design options for aerospace prismatic cell designs. Early in 1991, the first aerospace prismatic cell designs were built in a 6 Ah cell configuration. These cells were used to initially characterize performance in prismatic configurations and begin early life cycle testing. Soon after the 6 Ah cells were on test, several 22 Ah cells were built to test other options. The results of testing of these cells were used to identify potential problem areas for long lived cells and develop solutions to those problems. Following these two cell builds, a set of 7 Ah cells was built to evaluate improvements to the technology. To date results from these tests are very promising. Cycle lives in excess of 2,200 LEO cycles at 50 percent DoD were achieved with cells continuing on test. Results from these cell tests are discussed and data presented to demonstrate feasibility of this technology for aerospace programs.

  5. NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 24: The technical communications practices of US aerospace engineers and scientists: Results of the phase 1 SAE mail survey

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.

    1994-01-01

    The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis the technical communications practices of U.S. aerospace engineers and scientists affiliated with the Society of Automotive Engineers (SAE).

  6. NASA/DOD Aerospace Knowledge Diffusion Research Project. Report number 21: US aerospace industry librarians and technical information specialists as information intermediaries: Results of the phase 2 survey

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.

    1994-01-01

    The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DoD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis U.S. aerospace industry librarians and technical information specialists as information intermediaries.

  7. High temperature arc-track resistant aerospace insulation

    NASA Technical Reports Server (NTRS)

    Dorogy, William

    1994-01-01

    The topics are presented in viewgraph form and include the following: high temperature aerospace insulation; Foster-Miller approach to develop a 300 C rated, arc-track resistant aerospace insulation; advantages and disadvantages of key structural features; summary goals and achievements of the phase 1 program; performance goals for selected materials; materials under evaluation; molecular structures of candidate polymers; candidate polymer properties; film properties; and a detailed program plan.

  8. Reach and its Impact: NASA and US Aerospace Communities

    NASA Technical Reports Server (NTRS)

    Rothgeb, Matthew J.

    2011-01-01

    REACH is a European law that threatens to impact materials used within the US aerospace communities, including NASA. The presentation briefly covers REACH and generally, its perceived impacts to NASA and the aerospace community within the US.

  9. Applications of aerospace technology

    NASA Technical Reports Server (NTRS)

    Rouse, Doris J.

    1984-01-01

    The objective of the Research Triangle Institute Technology Transfer Team is to assist NASA in achieving widespread utilization of aerospace technology in terrestrial applications. Widespread utilization implies that the application of NASA technology is to benefit a significant sector of the economy and population of the Nation. This objective is best attained by stimulating the introduction of new or improved commercially available devices incorporating aerospace technology. A methodology is presented for the team's activities as an active transfer agent linking NASA Field Centers, industry associations, user groups, and the medical community. This methodology is designed to: (1) identify priority technology requirements in industry and medicine, (2) identify applicable NASA technology that represents an opportunity for a successful solution and commercial product, (3) obtain the early participation of industry in the transfer process, and (4) successfully develop a new product based on NASA technology.

  10. Trends in aerospace structures

    NASA Technical Reports Server (NTRS)

    Card, M. F.

    1978-01-01

    Recent developments indicate that there may soon be a revolution in aerospace structures. Increases in allowable operational stress levels, utilization of high-strength, high-toughness materials, and new structural concepts will highlight this advancement. Improved titanium and aluminum alloys and high-modulus, high-strength advanced composites, with higher specific properties than aluminum and high-strength nickel alloys, are expected to be the principal materials. Significant advances in computer technology will cause major changes in the preliminary design cycle and permit solutions of otherwise too-complex interactive structural problems and thus the development of vehicles and components of higher performance. The energy crisis will have an impact on material costs and choices and will spur the development of more weight-efficient structures. There will also be significant spinoffs of aerospace structures technology, particularly in composites and design/analysis software.

  11. The 1995 NASA Aerospace Battery Workshop

    NASA Technical Reports Server (NTRS)

    Brewer, J. C. (Compiler)

    1996-01-01

    This document contains the proceedings of the 28th annual NASA Aerospace Battery Workshop, hosted by the Marshall Space Flight Center on 28-30 Nov. 1995. The workshop was attended by scientists and engineers from various agencies of the U.S. Government, aerospace contractors, and battery manufacturers, as well as international participation in like kind from a number of countries around the world. The subjects covered included nickel-cadmium, nickel-hydrogen, nickel-metal hybride, and lithium based technologies, as well as flight and ground test data. Nickel-hydrogen modeling was also covered.

  12. The 1998 NASA Aerospace Battery Workshop

    NASA Technical Reports Server (NTRS)

    Brewer, Jeffrey C. (Compiler)

    1999-01-01

    This document contains the proceedings of the 31st annual NASA Aerospace Battery Workshop, hosted by the Marshall Space Flight Center on October 27-29, 1998. The workshop was attended by scientists and engineers from various agencies of the U.S. Government, aerospace contractors, and battery manufacturers, as well as international participation in like kind from a number of countries around the world. The subjects covered included nickel-hydrogen, silver-hydrogen, nickel-metal hydride, and lithium-based technologies, as well as results from destructive physical analyses on various cell chemistries.

  13. The 1992 NASA Aerospace Battery Workshop

    NASA Technical Reports Server (NTRS)

    Brewer, Jeffrey C. (Compiler)

    1993-01-01

    This document contains the proceedings of the 23rd annual NASA Aerospace Battery Workshop, hosted by the Marshall Space Flight Center on November 15-19, 1992. The workshop was attended by scientists and engineers from various agencies of the U.S. Government, aerospace contractors, and battery manufacturers, as well as international participation in like kind from a number of countries around the world. The subjects covered included nickel-cadmium, nickel-hydrogen, nickel-metal hydride, and lithium based technologies, as well as advanced technologies including sodium-sulfur and various bipolar designs.

  14. The 1997 NASA Aerospace Battery Workshop

    NASA Technical Reports Server (NTRS)

    Brewer, Jeffrey C. (Compiler)

    1998-01-01

    This document contains the proceedings of the 30th annual NASA Aerospace Battery Workshop, hosted by the Marshall Space Flight Center on November 18-20, 1997. The workshop was attended by scientists and engineers from various agencies of the U.S. Government, aerospace contractors, and battery manufacturers, as well as international participation in like kind from a number of countries around the world. The subjects covered included nickel-cadmium, nickel-hydrogen, nickel-metal hydride, lithium, lithium-ion, and silver-zinc technologies, as well as various aspects of nickel electrode design.

  15. Ninteenth Aerospace Mechanisms Symposium

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The proceedings of the 19th Aerospace Mechanisms Symposium are reported. Technological areas covered include space lubrication, bearings, aerodynamic devices, spacecraft/Shuttle latches, deployment, positioning, and pointing. Devices for spacecraft docking and manipulator and teleoperator mechanisms are also described.

  16. NASA/DoD Aerospace Knowledge Diffusion Research Project. XXXIII - Technical communications practices and the use of information technologies as reported by Dutch and U.S. aerospace engineers

    NASA Technical Reports Server (NTRS)

    Barclay, Rebecca O.; Pinelli, Thomas E.; Tan, Axel S. T.; Kennedy, John M.

    1993-01-01

    As part of Phase 4 of the NASA/DOD Aerospace Knowledge Diffusion Research Project, two studies were conducted that investigated the technical communications practices of Dutch and U.S. aerospace engineers and scientists. A self-administered questionnaire was distributed to aerospace engineers and scientists at the National Aerospace Laboratory (The Netherlands), and NASA Ames Research Center (U.S.), and the NASA Langley Research Center (U.S.). This paper presents responses of the Dutch and U.S. participants to selected questions about four of the seven project objectives: determining the importance of technical communications to aerospace engineering professionals, investigating the production of technical communications, examining the use and importance of computer and information technology, and exploring the use of electronic networks.

  17. The electronic transfer of information and aerospace knowledge diffusion

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Bishop, Ann P.; Barclay, Rebecca O.; Kennedy, John M.

    1992-01-01

    Increasing reliance on and investment in information technology and electronic networking systems presupposes that computing and information technology will play a motor role in the diffusion of aerospace knowledge. Little is known, however, about actual information technology needs, uses, and problems within the aerospace knowledge diffusion process. The authors state that the potential contributions of information technology to increased productivity and competitiveness will be diminished unless empirically derived knowledge regarding the information-seeking behavior of the members of the social system - those who are producing, transferring, and using scientific and technical information - is incorporated into a new technology policy framework. Research into the use of information technology and electronic networks by U.S. aerospace engineers and scientists, collected as part of a research project designed to study aerospace knowledge diffusion, is presented in support of this assertion.

  18. Biomedical applications of aerospace technology

    NASA Technical Reports Server (NTRS)

    Castles, T. R.

    1971-01-01

    Aerospace technology transfer to biomedical research problems is discussed, including transfer innovations and potential applications. Statistical analysis of the transfer activities and impact is also presented.

  19. The 2004 NASA Aerospace Battery Workshop

    NASA Technical Reports Server (NTRS)

    2006-01-01

    Topics covered include: Super NiCd(TradeMark) Energy Storage for Gravity Probe-B Relativity Mission; Hubble Space Telescope 2004 Battery Update; The Development of Hermetically Sealed Aerospace Nickel-Metal Hydride Cell; Serial Charging Test on High Capacity Li-Ion Cells for the Orbiter Advanced Hydraulic Power System; Cell Equalization of Lithium-Ion Cells; The Long-Term Performance of Small-Cell Batteries Without Cell-Balancing Electronics; Identification and Treatment of Lithium Battery Cell Imbalance under Flight Conditions; Battery Control Boards for Li-Ion Batteries on Mars Exploration Rovers; Cell Over Voltage Protection and Balancing Circuit of the Lithium-Ion Battery; Lithium-Ion Battery Electronics for Aerospace Applications; Lithium-Ion Cell Charge Control Unit; Lithium Ion Battery Cell Bypass Circuit Test Results at the U.S. Naval Research Laboratory; High Capacity Battery Cell By-Pass Switches: High Current Pulse Testing of Lithium-Ion; Battery By-Pass Switches to Verify Their Ability to Withstand Short-Circuits; Incorporation of Physics-Based, Spatially-Resolved Battery Models into System Simulations; A Monte Carlo Model for Li-Ion Battery Life Projections; Thermal Behavior of Large Lithium-Ion Cells; Thermal Imaging of Aerospace Battery Cells; High Rate Designed 50 Ah Li-Ion Cell for LEO Applications; Evaluation of Corrosion Behavior in Aerospace Lithium-Ion Cells; Performance of AEA 80 Ah Battery Under GEO Profile; LEO Li-Ion Battery Testing; A Review of the Feasibility Investigation of Commercial Laminated Lithium-Ion Polymer Cells for Space Applications; Lithium-Ion Verification Test Program; Panasonic Small Cell Testing for AHPS; Lithium-Ion Small Cell Battery Shorting Study; Low-Earth-Orbit and Geosynchronous-Earth-Orbit Testing of 80 Ah Batteries under Real-Time Profiles; Update on Development of Lithium-Ion Cells for Space Applications at JAXA; Foreign Comparative Technology: Launch Vehicle Battery Cell Testing; 20V, 40 Ah Lithium Ion Polymer

  20. Aerospace applications of mass market MEMS products

    NASA Astrophysics Data System (ADS)

    Bauer, Karin; Kroetz, Gerhard; Schalk, Josef; Mueller, Gerhard

    2002-07-01

    Aerospace applications of MEMS products, originally developed for automotive mass markets, are discussed. Various sensor examples with a high dual use potential are presented: inertial sensing, flow and gas sensing, robust micro sensors including SiC- and GaN-based devices, as well as first approaches towards flexible and distributed microsystems. In Europe the automotive industry is one of the main MEMS market drivers, simply because of the sheer size of this market and Europe's strong position in this industrial field. Main MEMS activities are development and integration of vehicle dynamics sensing systems, passenger safety and navigation systems, air and fuel intake systems, as well as sensor systems for exhaust gas after treatment and climate control. Benefits on the customer side are increased safety, passenger comfort and reduced fuel consumption. Benefits on the manufacturer's side are increased sub-system integration, modularity and reduced production cost. In the future the aerospace industry is likely to benefit from the introduction of micro-systems for the same reasons as the automotive industry. Interests of the aerospace industry are increasing safety and reliability of airplane operation, health and state monitoring of fuselage and airplane subsystems as well as improving service and maintenance procedures. In comparison to automotive applications, the numbers of devices needed is likely to be much smaller, however, new challenges arise in so far as distributed sensing and actuating microsystems will be needed. The idea is to identify and to exploit synergies between automotive mass market MEMS applications and lower-volume aerospace ones. The effort necessary to meet aerospace requirements and the extent of necessary trade-offs in customizing automotive MEMS is addressed considering the above-mentioned examples.

  1. Women, Innovation and Aerospace Event

    NASA Image and Video Library

    2012-03-08

    Lori Garver (far right) NASA Deputy Administrator, participates in a panel discussion at the Women, Innovation and Aerospace event celebrating Women's History Month at the George Washington University Jack Morton Auditorium, Thursday, March 8, 2012 in Washington. Garver is seen with Kathy Sullivan, NOAA Deputy Administrator; Catherine Didion, Senior Fellow, National Academy of Engineering; Marcia Smith, President, spacepolicyonline.com and Veronica Villalobos, Director, Office of Diversity and Inclusion, Office of Personnel Management (far left). The WIA day-long event will help to foster a discussion for students and early career professionals about how to continue to encourage women to enter and succeed in the field of aerospace. Photo Credit: (NASA/Carla Cioffi)

  2. Third Aerospace Environmental Technology Conference

    NASA Technical Reports Server (NTRS)

    Whitaker, A. F. (Editor); Cross, D. R. (Editor); Caruso, S. V. (Editor); Clark-Ingram, M. (Editor)

    1999-01-01

    The elimination of CFC's, Halons, TCA, other ozone depleting chemicals, and specific hazardous materials is well underway. The phaseout of these chemicals has mandated changes and new developments in aerospace materials and processes. We are beyond discovery and initiation of these new developments and are now in the implementation phase. This conference provided a forum for materials and processes engineers, scientists, and managers to describe, review, and critically assess the evolving replacement and clean propulsion technologies from the standpoint of their significance, application, impact on aerospace systems, and utilization by the research and development community. The use of these new technologies, their selection and qualification, their implementation, and the needs and plans for further developments are presented.

  3. Polymer and ceramic nanocomposites for aerospace applications

    NASA Astrophysics Data System (ADS)

    Rathod, Vivek T.; Kumar, Jayanth S.; Jain, Anjana

    2017-11-01

    This paper reviews the potential of polymer and ceramic matrix composites for aerospace/space vehicle applications. Special, unique and multifunctional properties arising due to the dispersion of nanoparticles in ceramic and metal matrix are briefly discussed followed by a classification of resulting aerospace applications. The paper presents polymer matrix composites comprising majority of aerospace applications in structures, coating, tribology, structural health monitoring, electromagnetic shielding and shape memory applications. The capabilities of the ceramic matrix nanocomposites to providing the electromagnetic shielding for aircrafts and better tribological properties to suit space environments are discussed. Structural health monitoring capability of ceramic matrix nanocomposite is also discussed. The properties of resulting nanocomposite material with its disadvantages like cost and processing difficulties are discussed. The paper concludes after the discussion of the possible future perspectives and challenges in implementation and further development of polymer and ceramic nanocomposite materials.

  4. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 55: Career goals and educational preparation of aerospace engineering and science students: An international perspective

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Kennedy, John M.; Barclay, Rebecca O.

    1995-01-01

    Results are presented of a survey of aerospace engineering and science students conducted in India, Japan, Russia, the United Kingdom, and the United States. The similarities and differences among aerospace engineering and science students from the five countries are examined in the context of two general aspects of educational experience. First, the extent to which students differ regarding the factors that led to the choice of a career in aerospace, their current levels of satisfaction with that choice, and career-related goals and objectives is considered. Second, the importance of certain communications/information-use skills for professional use is examined, as well as the frequency of use and importance of specific information sources and products to meet students' educational needs. Overall, the students who participated in this research remain relatively happy with the choice of a career in aerospace engineering, despite pessimism in some quarters about the future of the industry. Regardless of national identity, aerospace engineering and science students appear to share a similar vision of the profession in terms of their career goals and aspirations. The data also indicate that aerospace engineering and science students are well aware of the importance of communications/information-use skills to professional success and that competency in these skills will help them to be productive members of their profession. Collectively, all of the students appear to use and value similar information sources and products, although some differences appear by country.

  5. An Assessment of the Effectiveness of Selected Aerospace Education Workshops in Tennessee

    ERIC Educational Resources Information Center

    Maupin, Pauline Hicks

    1976-01-01

    Data from questionnaires indicated that the Tennessee Aerospace Education Workshops were successful in reaching their stated goals, which included developing a greater awareness of aerospace education and helping teachers incorporate more aerospace education in classroom activities. (MLH)

  6. 76 FR 65750 - Aerospace Safety Advisory Panel; Charter Renewal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-24

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (11-105)] Aerospace Safety Advisory Panel; Charter Renewal AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of renewal and amendment of the charter of the NASA Aerospace Safety Advisory Panel. SUMMARY: Pursuant to...

  7. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 35: The US government technical report and aerospace knowledge diffusion: Results of an on-going investigation

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Khan, A. Rahman; Barclay, Rebecca O.; Kennedy, John M.

    1993-01-01

    The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded (U.S.) R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this paper, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from two surveys (one of five studies) of our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report and close with a brief overview of on-going research into the use of the U.S. government technical report as a rhetorical device for transferring federally funded aerospace R&D.

  8. 78 FR 69516 - DeltaPoint Capital IV, L.P.; License No. 02/02-0662; Notice Seeking Exemption Under the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ... 107.730). DeltaPoint Capital IV, L.P. provided financing to BioMaxx, Inc., 1 Fishers Road, Suite 160...., an Associate of DeltaPoint Capital IV, L.P., owns more than ten percent of BioMaxx, Inc. Therefore...

  9. National Aerospace Professional Societies and Associations and Organizations

    NASA Technical Reports Server (NTRS)

    Henderson, Arthur J., Jr.

    2000-01-01

    This session will highlight several highly recognized National Technical and Professional Aerospace Societies, Associations and Organizations that are dedicated to the advancement of the theories, practices and unique applications of Science, Engineering and related Aerospace Activities ongoing in the United States. The emphasis will be on at least three (3) Aerospace Organizations, while reference many others. This paper will provide a wealth of educational references, information, opportunities and services available through many of the National and Local Chapter Affiliates, associated with the respective associations. Again, all experience and knowledge levels (K-12) will benefit from this information and reference material. Reference materials and other points of contact will be made available to all attendees.

  10. Characterizing the Resolved M6 Dwarf Twin LP 318-218AB

    NASA Astrophysics Data System (ADS)

    Moreno Hilario, Elizabeth; Burgasser, Adam J.; Bardalez Gagliuffi, Daniella; Tamiya, Tomoki

    2017-01-01

    The lowest-mass stars and brown dwarfs are among the most common objects in the Milky Way Galaxy, but theories of their formation and evolution remain poorly constrained. Binary systems are important for understanding the formation of these objects and for making direct orbit and mass measurements to validate evolutionary theories. We report the discovery of LP 318-218, a high proper motion late M dwarf, as a near equal-brightness binary system with a separation of 0.72 arcseconds. Resolved near-infrared spectroscopy confirms the components as nearly identical M6 twins. We using our resolved photometry and spectroscopy to estimate the distance, projected separation and tangential velocity of the system, and confirm common proper motion. We also perform atmosphere model fits to the resolved spectra to assess their physical properties. We place LP 318-218 in context with other widely-separated late M dwarf binaries.

  11. Introduction: Aims and Requirements of Future Aerospace Vehicles. Chapter 1

    NASA Technical Reports Server (NTRS)

    Rodriguez, Pedro I.; Smeltzer, Stanley S., III; McConnaughey, Paul (Technical Monitor)

    2001-01-01

    The goals and system-level requirements for the next generation aerospace vehicles emphasize safety, reliability, low-cost, and robustness rather than performance. Technologies, including new materials, design and analysis approaches, manufacturing and testing methods, operations and maintenance, and multidisciplinary systems-level vehicle development are key to increasing the safety and reducing the cost of aerospace launch systems. This chapter identifies the goals and needs of the next generation or advanced aerospace vehicle systems.

  12. NASA Aerospace Flight Battery Program: Generic Safety, Handling and Qualification Guidelines for Lithium-Ion (Li-Ion) Batteries; Availability of Source Materials for Lithium-Ion (Li-Ion) Batteries; Maintaining Technical Communications Related to Aerospace Batteries (NASA Aerospace Battery Workshop). Volume 1, Part 1

    NASA Technical Reports Server (NTRS)

    Manzo, Michelle A.; Brewer, Jeffrey C.; Bugga, Ratnakumar V.; Darcy, Eric C.; Jeevarajan, Judith A.; McKissock, Barbara I.; Schmitz, Paul C.

    2010-01-01

    This NASA Aerospace Flight Battery Systems Working Group was chartered within the NASA Engineering and Safety Center (NESC). The Battery Working Group was tasked to complete tasks and to propose proactive work to address battery related, agency-wide issues on an annual basis. In its first year of operation, this proactive program addressed various aspects of the validation and verification of aerospace battery systems for NASA missions. Studies were performed, issues were discussed and in many cases, test programs were executed to generate recommendations and guidelines to reduce risk associated with various aspects of implementing battery technology in the aerospace industry. This document contains Part 1 - Volume I: Generic Safety, Handling and Qualification Guidelines for Lithium-Ion (Li-Ion) Batteries, Availability of Source Materials for Lithium-Ion (Li-Ion) Batteries, and Maintaining Technical Communications Related to Aerospace Batteries (NASA Aerospace Battery Workshop).

  13. 75 FR 16662 - Airworthiness Directives; Kelly Aerospace Energy Systems, LLC Rebuilt Turbochargers

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... Airworthiness Directives; Kelly Aerospace Energy Systems, LLC Rebuilt Turbochargers AGENCY: Federal Aviation... airworthiness directive (AD) for certain Kelly Aerospace Energy Systems, LLC (KAES) rebuilt turbochargers. This... Federal holidays. Fax: (202) 493-2251. Contact Kelly Aerospace Energy Systems, LLC, 2900 Selma Highway...

  14. LP DAAC MEaSUREs Project Artifact Tracking Via the NASA Earthdata Collaboration Environment

    NASA Astrophysics Data System (ADS)

    Bennett, S. D.

    2015-12-01

    The Land Processes Distributed Active Archive Center (LP DAAC) is a NASA Earth Observing System (EOS) Data and Information System (EOSDIS) DAAC that supports selected EOS Community non-standard data products such as the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) Global Emissivity Database (GED), and also supports NASA Earth Science programs such as Making Earth System Data Records for Use in Research Environments (MEaSUREs) to contribute in providing long-term, consistent, and mature data products. As described in The LP DAAC Project Lifecycle Plan (Daucsavage, J.; Bennett, S., 2014), key elements within the Project Inception Phase fuse knowledge between NASA stakeholders, data producers, and NASA data providers. To support and deliver excellence for NASA data stewardship, and to accommodate long-tail data preservation with Community and MEaSUREs products, the LP DAAC is utilizing NASA's own Earthdata Collaboration Environment to bridge stakeholder communication divides. By leveraging a NASA supported platform, this poster describes how the Atlassian Confluence software combined with a NASA URS/Earthdata support can maintain each project's members, status, documentation, and artifact checklist. Furthermore, this solution provides a gateway for project communities to become familiar with NASA clients, as well as educating the project's NASA DAAC Scientists for NASA client distribution.

  15. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 69: Writing for the Aerospace Industry. Chapter 3; The Practice of Technical and Scientific Communication: Writing in Professional Contexts

    NASA Technical Reports Server (NTRS)

    Barclay, Rebecca O.; Pinelli, Thomas E.

    1997-01-01

    The large and complex aerospace industry, which employed approximately 850,000 people in 1994 (Aerospace Facts, 1994-95, p. 11), plays a vital role in the nation's economy. Although only a small percentage of those employed in aerospace are technical communicators, they perform a wide variety of communication duties in government and the private sector.

  16. 77 FR 42353 - Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-18

    ... SMALL BUSINESS ADMINISTRATION [License No. 06/06-0335] Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Escalate Capital Partners SBIC I, L.P., 300 West 6th Street, Suite 2250...

  17. 75 FR 71785 - Escalate Capital Partners SBIC I, L.P., License No. 06/06-0335; Notice Seeking Exemption Under...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... SMALL BUSINESS ADMINISTRATION Escalate Capital Partners SBIC I, L.P., License No. 06/06-0335; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Escalate Capital Partners, SBIC I, L.P., 300 W. 6th Street, Suite 2250...

  18. 76 FR 619 - Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... SMALL BUSINESS ADMINISTRATION [License No. 06/06-0335] Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Escalate Capital Partners, SBIC I, L.P., 300 W. 6th Street, Suite 2250...

  19. 76 FR 17180 - KLH Capital II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-28

    ... SMALL BUSINESS ADMINISTRATION [License No. 04/04-0296] KLH Capital II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that KLH Capital, L.P., 101 East Kennedy Boulevard, Suite 3925, Tampa, FL, 33602 a Federal...

  20. 76 FR 68803 - Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ... SMALL BUSINESS ADMINISTRATION [License No. 06/06-0335] Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Escalate Capital Partners, SBIC I, L.P., 300 W. 6th Street, Suite 2250...

  1. 75 FR 45178 - Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-02

    ... SMALL BUSINESS ADMINISTRATION Escalate Capital Partners SBIC I, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Escalate Capital Partners SBIC I, L.P., 300 W. 6th Street, Suite 2250, Austin, TX 78701, a Federal...

  2. 77 FR 37728 - GMB Mezzanine Capital II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ... SMALL BUSINESS ADMINISTRATION [License No. 05/05-0299] GMB Mezzanine Capital II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that GMB Mezzanine Capital II, L.P., 50 South Sixth Street, Suite 1460, Minneapolis, MN...

  3. 75 FR 76037 - HAVI Logistics, North America a Subsidiary of HAVI Group, LP Including On-Site Leased Workers of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-07

    ... Logistics, North America a Subsidiary of HAVI Group, LP Including On-Site Leased Workers of Express Personnel Services and the La Salle Network, Bloomingdale, IL; Havi Logistics, North America, Lisle, IL..., applicable to workers of HAVI Logistics, North America, a subsidiary of HAVI Group, LP, including on-site...

  4. NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 25: The technical communications practices of British aerospace engineers and scientists: Results of the phase 4 RAeS mail survey

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.

    1994-01-01

    The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis the technical communications practices of British aerospace engineers and scientists.

  5. NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 33: The technical communications practices of US aerospace engineers and scientists: Results of the phase 1 AIAA mail survey

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.

    1995-01-01

    The U.S. government technical report is a primary means by which the results of federally funded research and development (R&D) are transferred to the U.S. aerospace industry. However, little is known about this information product in terms of its actual use, importance, and value in the transfer of federally funded R&D. To help establish a body of knowledge, the U.S. government technical report is being investigated as part of the NASA/DOD Aerospace Knowledge Diffusion Research Project. In this report, we summarize the literature on technical reports and provide a model that depicts the transfer of federally funded aerospace R&D via the U.S. government technical report. We present results from our investigation of aerospace knowledge diffusion vis-a-vis the U.S. government technical report, and present the results of research that investigated aerospace knowledge diffusion vis-a-vis the technical communications practices of U.S. aerospace engineers and scientists who are members of the American Institute of Aeronautics and Astronautics (AIAA).

  6. Oklahoma Aerospace Intellectual Capital/Educational Recommendations: An Inquiry of Oklahoma Aerospace Executives

    ERIC Educational Resources Information Center

    Nelson, Erin M.

    2010-01-01

    Scope and Method of Study: The purpose of this qualitative study was to conduct detailed personal interviews with aerospace industry executives/managers from both the private and military sectors from across Oklahoma to determine their perceptions of intellectual capital needs of the industry. Interviews with industry executives regarding…

  7. Protons, Aerospace, and Electronics: A National Interest

    NASA Technical Reports Server (NTRS)

    Label, Kenneth A.; Turflinger, Thomas L.

    2017-01-01

    The aerospace and semiconductor industries lost 2000 hours annually of research access when IUCF closed. An ad hoc team between the U.S. government and industry was formed to evaluate other facility options. In this presentation, we will discuss: 1) Why aerospace, semiconductor manufacturers, and others are interested in proton facility access, as well as, 2) Some of the basics of a typical test for electronics, and 3) We'll conclude with the brief current status on progress.

  8. Protons, Aerospace, and Electronics: A National Interest

    NASA Technical Reports Server (NTRS)

    LaBel, Kenneth A.; Turflinger, Thomas L.

    2018-01-01

    The aerospace and semiconductor industries lost approximately 2000 hours annually of research access when IUCF closed. An ad hoc team between the U.S. government and industry was formed to evaluate other facility options. In this presentation, we will discuss: 1) Why aerospace, semiconductor manufacturers, and others are interested in proton facility access, as well as, 2) Some of the basics of a typical tests for electronics, and 3) We'll conclude with the brief current status on progress.

  9. Protons, Aerospace, and Electronics: A National Interest

    NASA Technical Reports Server (NTRS)

    LaBel, Kenneth A.; Turflinger, Thomas L.

    2018-01-01

    The aerospace and semiconductor industries lost approx. 2000 hours annually of research access when IUCF closed. An ad hoc team between the U.S. government and industry was formed to evaluate other facility options. In this presentation, we will discuss: 1) Why aerospace, semiconductor manufacturers, and others are interested in proton facility access, as well as, 2) Some of the basics of a typical test for electronics, and 3) We"ll conclude with the brief current status on progress.

  10. Directory of aerospace safety specialized information sources

    NASA Technical Reports Server (NTRS)

    Fullerton, E. A.; Rubens, L. S.

    1973-01-01

    A directory is presented to make available to the aerospace safety community a handbook of organizations and experts in specific, well-defined areas of safety technology. It is designed for the safety specialist as an aid for locating both information sources and individual points of contact (experts) in engineering related fields. The file covers sources of data in aerospace design, tests, as well as information in hazard and failure cause identification, accident analysis, materials characteristics, and other related subject areas. These 171 organizations and their staff members, hopefully, should provide technical information in the form of documentation, data and consulting expertise. These will be sources that have assembled and collated their information, so that it will be useful in the solution of engineering problems. One of the goals of the project in the United States that have and are willing to share data of value to the aerospace safety community.

  11. Acting Administrator Lightfoot Visits Ball Aerospace

    NASA Image and Video Library

    2017-04-06

    Leanne Presley, Operational Land Imager-2 (OLI-2) program manager at Ball Aerospace, left, speaks with acting NASA Deputy Administrator Lesa Roe, center, and acting NASA Administrator Robert Lightfoot in front of a thermal vacuum chamber used to test satellite optics, Thursday, April 6, 2017 during a visit to Ball Aerospace in Boulder, Colo. The Operation Land Imager-2 (OLI-2) is being build for Landsat 9, a collaboration between NASA and the U.S. Geological Survey that will continue the Landsat Program's 40-year data record of monitoring the Earth's landscapes from space. Photo Credit: (NASA/Joel Kowsky)

  12. The 1993 NASA Aerospace Battery Workshop

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brewer, J.C.

    1994-02-01

    This document contains the proceedings of the 26th annual NASA Aerospace Battery Workshop, hosted by the Marshall Space Flight Center on 16-18 Nov. 1993. The workshop was attended by scientists and engineers from various agencies of the U.S. Government, aerospace contractors, and battery manufacturers, as well as international participation in like kind from a number of countries around the world. The subjects covered included nickel-cadmium, nickel-hydrogen, nickel-metal hydride, and lithium based technologies, as well as advanced technologies including various bipolar designs. Separate abstracts have been prepared for papers from this report.

  13. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 43: The role of information resource training in aerospace education. Expanded version

    NASA Technical Reports Server (NTRS)

    Lawrence, Barbara; Pinelli, Thomas E.; Barclay, Rebecca O.; Kennedy, John M.; Holloway, Karen

    1994-01-01

    Information resource instruction for undergraduate aerospace engineering students has traditionally been limited to an occasional part of the education process--a written paper required in the capstone design course or a library tour. Efforts to encourage the use of aerospace literature and information resources have been made in the past decade, with a recent push from information and, especially, networking technology. This paper presents data from a survey of U.S. aerospace engineering students regarding their instruction in the use of information resources. We find that more than 25 percent of the students surveyed had no instruction in technical communications skills or the use of information resources. We consider the need for instruction in the use of information resources and technical communications skills and the opportunities presented for improvement.

  14. 78 FR 77770 - Aldine Capital Fund II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... SMALL BUSINESS ADMINISTRATION [License No. 05/05-0310] Aldine Capital Fund II, L.P.; Notice Seeking Exemption Under Section 312 of the Small Business Investment Act, Conflicts of Interest Notice is hereby given that Aldine Capital Fund II, L.P., 30 West Monroe Street, Suite 710, Chicago, IL 60603, a...

  15. Hexavalent Chromium Free Coatings Projects for Aerospace Applications

    DTIC Science & Technology

    2012-08-01

    1-Evaluate trivalent chromium pretreatment (TCP) for use on aluminum  2-Evaluate three hexavalent chrome free alternatives to DoD-P-15328 wash...UNCLASSIFIED UNCLASSIFIED Hexavalent Chromium Free Coatings Projects for Aerospace Applications Report Documentation Page Form...COVERED 00-00-2012 to 00-00-2012 4. TITLE AND SUBTITLE Hexavalent Chromium Free Coatings Projects for Aerospace Applications 5a. CONTRACT NUMBER

  16. Damping in aerospace composite materials

    NASA Astrophysics Data System (ADS)

    Agneni, A.; Balis Crema, L.; Castellani, A.

    Experimental results are presented on specimens of carbon and Kevlar fibers in epoxy resin, materials used in many aerospace structures (control surfaces and wings in aircraft, large antennas in spacecraft, etc.). Some experimental methods of estimating damping ratios are first reviewed, either in the time domain or in the frequency domain. Some damping factor estimates from experimental tests are then shown; in order to evaluate the effects of the aerospace environment, damping factors have been obtained in a typical range of temperature, namely between +120 C and -120 C, and in the pressure range from room pressure to 10 exp -6 torr. Finally, a theoretical approach for predicting the bounds of the damping coefficients is shown, and prediction data are compared with experimental results.

  17. Aerospace applications of batteries

    NASA Technical Reports Server (NTRS)

    Habib, Shahid

    1993-01-01

    NASA has developed battery technology to meet the demanding requirements for aerospace applications; specifically, the space vacuum, launch loads, and high duty cycles. Because of unique requirements and operating environments associated with space applications, NASA has written its own standards and specifications for batteries.

  18. 75 FR 45075 - Airworthiness Directives; Eclipse Aerospace, Inc. Model EA500 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-02

    ... Airworthiness Directives; Eclipse Aerospace, Inc. Model EA500 Airplanes AGENCY: Federal Aviation Administration... in the Federal Register on July 9, 2010 (75 FR 39472), and applies to certain Eclipse Aerospace, Inc... Federal holidays. For service information identified in this proposed AD, contact Eclipse Aerospace, Inc...

  19. 75 FR 20265 - Airworthiness Directives; Liberty Aerospace Incorporated Model XL-2 Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-19

    ... Airworthiness Directives; Liberty Aerospace Incorporated Model XL-2 Airplanes AGENCY: Federal Aviation...-08- 05, which applies to certain Liberty Aerospace Incorporated Model XL-2 airplanes. AD 2009-08-05...), the Director of the Federal Register approved the incorporation by reference of Liberty Aerospace, Inc...

  20. 76 FR 51350 - Aerospace Executive Service Trade Mission (AESTM) to Seoul, Korea

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... Korean governments and private aerospace and defense companies, the AESTM service at this major aerospace..., government officials, senior company managers, and high-level executives involved in the aerospace and... display company literature and conduct meetings with visitors to the air show. Company information and...