Science.gov

Sample records for affecting plastic instability

  1. Plastic instabilities in statically and dynamically loaded spherical vessels

    SciTech Connect

    Duffey, Thomas A; Rodriguez, Edward A

    2010-01-01

    Significant changes were made in design limits for pressurized vessels in the 2007 version of the ASME Code (Section VIII, Div. 3) and 2008 and 2009 Addenda. There is now a local damage-mechanics based strain-exhaustion limit as well as the well-known global plastic collapse limit. Moreover, Code Case 2564 (Section VIII, Div. 3) has recently been approved to address impulsively loaded vessels. It is the purpose of this paper to investigate the plastic collapse limit as it applies to dynamically loaded spherical vessels. Plastic instabilities that could potentially develop in spherical shells under symmetric loading conditions are examined for a variety of plastic constitutive relations. First, a literature survey of both static and dynamic instabilities associated with spherical shells is presented. Then, a general plastic instability condition for spherical shells subjected to displacement controlled and impulsive loading is given. This instability condition is evaluated for six plastic and visco-plastic constitutive relations. The role of strain-rate sensitivity on the instability point is investigated. Calculations for statically and dynamically loaded spherical shells are presented, illustrating the formation of instabilities as well as the role of imperfections. Conclusions of this work are that there are two fundamental types of instabilities associated with failure of spherical shells. In the case of impulsively loaded vessels, where the pulse duration is short compared to the fundamental period of the structure, one instability type is found not to occur in the absence of static internal pressure. Moreover, it is found that the specific role of strain-rate sensitivity on the instability strain depends on the form of the constitutive relation assumed.

  2. Directional plasticity of clay showing instability

    NASA Astrophysics Data System (ADS)

    Fortuna, Sonia

    2010-06-01

    A graphical approach is used to sketch the field of small plastic strains (epsilon < 0.1 %) of Pisa clay along different axi-symmetric stress paths associated to a partial confining stress reduction. Within the classic framework of elasto-plasticity, volumetric and deviatoric plastic strains contours are determined from data obtained from triaxial tests, assuming a cross-anisotropic hypo-elastic formulation calibrated on a wide set of tests and with non linear evolution of the elastic moduli calibrated along a quasi-1D swelling stress path. The evolutions of the plastic strains and of the plastic strain vectors are shown along the stress path directly explored with tests and along virtual paths interpolated from the actual data along intermediate directions at various strain levels.

  3. Tensile instabilities for porous plasticity models

    SciTech Connect

    BRANNON,REBECCA M.

    2000-02-29

    Several concepts (and assumptions) from the literature for porous metals and ceramics have been synthesized into a consistent model that predicts an admissibility limit on a material's porous yield surface. To ensure positive plastic work, the rate at which a yield surface can collapse as pores grow in tension must be constrained.

  4. Plastic instability in omega forming alloy systems

    NASA Astrophysics Data System (ADS)

    Banerjee, S.

    2006-11-01

    The plastic flow behaviour of two ω forming systems namely ordered Nb-40Ti-15Al and metastable Zr-Nb alloys has been studied over a range of strain rate and temperature to establish the domain of serrated flow or Protevin-Le Chatelier (PLC) effect. The observed features of serrated flow in these alloys are strikingly similar to that observed during PLC effect of solid solution alloys. Samples deformed in the serrated flow regime have been studied at different levels of magnification using light, scanning electron and transmission electron microscopy. A very characteristic feature of deformation in these alloys has been the presence precipitate free channels, microbands and deformation bands. The proposed mechanism of serrated flow involves creation of soft channels formed by shearing of ω-particles and dynamic restoration of ω-particles within the soft channel resulting in pinning of dislocation. It appears that this is the characteristic feature of deformation of ω forming system exhibiting PLC effect.

  5. Removal of plastic instabilities by reversal of the applied stress

    NASA Astrophysics Data System (ADS)

    Saada, Georges; Kruml, Tomas

    2013-01-01

    This paper presents experiments showing that the inversion of the sense of the applied stress on a specimen deformed in tension (respectively compression) results in the removal of mechanical instabilities such as the yield point and the Lüders band in a ferritic steel or serrations in an Al-Mg alloy. We show that this behaviour is connected neither to the mechanical set-up (tension, torsion, …) , nor to the crystal geometry, but to the development of antagonist internal stresses during plastic flow. We develop a multi-domain analysis of the effect of these stresses and emphasize the importance of the analysis of the elastic-plastic transition.

  6. Affective instability in patients with chronic pain: a diary approach.

    PubMed

    Rost, Silke; Van Ryckeghem, Dimitri M L; Koval, Peter; Sütterlin, Stefan; Vögele, Claus; Crombez, Geert

    2016-08-01

    Affective instability, conceptualized as fluctuations in mood over time, has been related to ill-health and psychopathology. In this study, we examined the role of affective instability on daily pain outcomes in 70 patients with chronic pain (Mage = 49.7 years; 46 females) using an end-of-day diary. During a baseline phase, patients completed self-reported questionnaires of pain severity, pain duration, disability, depression, and anxiety. During a subsequent diary phase, patients filled out an electronic end-of-day diary over 14 consecutive days assessing daily levels of pain severity, disability, cognitive complaints, negative affect (NA) and positive affect. Affective instability was operationalized as the mean square of successive differences in daily mood (separately for NA and positive affect), which takes into account the size of affective changes over consecutive days. Results indicated that NA instability was positively associated with daily disability, beyond the effects of daily pain severity. Furthermore, NA instability moderated the relationship between daily pain severity and daily disability and the relationship between daily pain severity and daily cognitive complaints. Positive affect instability, however, showed to be unrelated to all outcomes. Current findings extend previous results and reveal the putative role of affective instability on pain-related outcomes and may yield important clinical implications. Indeed, they suggest that targeting NA instability by improving emotion regulation skills may be a strategy to diminish disability and cognitive complaints in patients with chronic pain. PMID:27075427

  7. Affective instability: toward an integration of neuroscience and psychological perspectives.

    PubMed

    Koenigsberg, Harold W

    2010-02-01

    Affective instability is a prominent feature of a wide variety of psychiatric and neurological disorders, yet it has not been systematically studied. It encompasses a number of distinct phenomena, including: (1) frequent affective category shifts, (2) disturbances in affect intensity, (3) excessively rapid emotion rise-times, (4) delayed return to emotional baseline, (5) excessive reactivity to psychosocial cues, (6) endogenously driven, random, chaotic or rapid-cycling changes, and (7) overdramatic expression. To further clarify the construct of affective instability, this article examines the manifestations of affective instability in a range of psychiatric and neurologic disorders, reviews relevant neurobiological and psychological emotion regulatory processes, and considers the psychology of affective instability. PMID:20205499

  8. Affective instability, family history of mood disorders, and neurodevelopmental disturbance.

    PubMed

    Berenbaum, Howard; Bredemeier, Keith; Boden, M Tyler; Thompson, Renee J; Milanak, Melissa

    2011-07-01

    The association between affective instability and both family history of mood disorders and signs of neurodevelopmental disturbance was examined in a sample of 303 adults. Affective instability was measured using the borderline personality disorder "affective instability due to a marked reactivity of mood" diagnostic criterion as assessed dimensionally using the Personality Disorder Interview--IV. Participants were interviewed concerning family history of mood disorders, with family history coded using the Family History Research Diagnostic Criteria. Minor physical anomalies, inconsistent hand use, and dermatoglyphic asymmetries were used to index neurodevelopmental disturbance. Affective instability was associated with elevated rates of family history of mood disorders, particularly among individuals who exhibited inconsistent hand use and greater minor physical anomalies. These associations could not be accounted for by shared variance with age, gender, negative affect, or personal history of mood disorders. PMID:22448768

  9. Colored plastic mulch microclimates affect strawberry fruit yield and quality.

    PubMed

    Shiukhy, Saeid; Raeini-Sarjaz, Mahmoud; Chalavi, Vida

    2015-08-01

    Significant reduction of strawberry (Fragaria × ananassa, Duch.) fruit yield and quality, as a consequence of conventional cultivation method, is common in the Caspian Sea region, Iran. Recently, growers started using plastic mulches to overcome these shortcomings. Plastic mulches have different thermal and radiation properties and could affect strawberry fruit yield and quality. In the present study, the effect of different colored plastic mulches (black, red, and white) along with conventional practice was tested on yield and quality of strawberry Camarosa cultivar, in a completely randomized block design. Colored plastic mulches had highly significant effect on fruit weight, size, and phytochemical contents. In the most harvest times, mean fruit weight was significantly higher in red plastic relative to white and control treatments. Total fruit weight of plastic mulches was not significantly different, while all were statistically higher than that of control. Fruit size significantly increased over red plastic mulch. Total fruit numbers over plastic mulches were significantly higher than that of control treatment. The content of phenolic compounds was similar between treatments, while anthocyanin content, IC(50) value, and flavonoid content significantly were affected by colored plastics. In conclusion, colored plastic mulches could affect strawberry fruit weight and quality through altering strawberry thermal and radiation environment. PMID:25348886

  10. Colored plastic mulch microclimates affect strawberry fruit yield and quality

    NASA Astrophysics Data System (ADS)

    Shiukhy, Saeid; Raeini-Sarjaz, Mahmoud; Chalavi, Vida

    2015-08-01

    Significant reduction of strawberry ( Fragaria × ananassa, Duch.) fruit yield and quality, as a consequence of conventional cultivation method, is common in the Caspian Sea region, Iran. Recently, growers started using plastic mulches to overcome these shortcomings. Plastic mulches have different thermal and radiation properties and could affect strawberry fruit yield and quality. In the present study, the effect of different colored plastic mulches (black, red, and white) along with conventional practice was tested on yield and quality of strawberry Camarosa cultivar, in a completely randomized block design. Colored plastic mulches had highly significant effect on fruit weight, size, and phytochemical contents. In the most harvest times, mean fruit weight was significantly higher in red plastic relative to white and control treatments. Total fruit weight of plastic mulches was not significantly different, while all were statistically higher than that of control. Fruit size significantly increased over red plastic mulch. Total fruit numbers over plastic mulches were significantly higher than that of control treatment. The content of phenolic compounds was similar between treatments, while anthocyanin content, IC50 value, and flavonoid content significantly were affected by colored plastics. In conclusion, colored plastic mulches could affect strawberry fruit weight and quality through altering strawberry thermal and radiation environment.

  11. International conference on Statistical Mechanics of Plasticity and Related Instabilities

    NASA Astrophysics Data System (ADS)

    2006-11-01

    The papers compiled in this volume are based on talks and posters given at the International Conference on "Statistical Mechanics of Plasticity and Related Instabilities", (SMPRI 2005), held at the Materials Research Center of the Indian Institute of Science, Bangalore, India, from August 29 to September 2, 2005. Our aim in organizing SMPRI 2005 was to promote and enhance interactions between researchers from the statistical physics, materials science and solid mechanics communities. While predicting the (macroscopic) deformation properties of materials is a classical topic of materials science and materials mechanics, statistical physicists have become increasingly interested in the collective processes which control the irreversible deformation of matter on microscopic and mesoscopic scales. The SMPRI 2005 meeting has been a forum for the exchange of concepts, research ideas, and results among these communities. We hope that the contributions contained in this proceedings volume will not only help to continue and deepen this exchange, but also to disseminate the results beyond the, necessarily limited, circle of the actual participants. We want to thank all contributors for the work in preparing their manuscripts. We are grateful to the institutions which have supported this conference, in particular the Asian Office for Aerospace Research and Developement (AOARD/AFOSR), the Jawaharlal Nehru Center for Advanced Scientific Research, the Indian Center for Scientific and Industrial Research, the Indian Defense Research and Developement Organization, The Abdus Salam International Center for Theoretical Physics, Italy, the Indian Institute of Science, in particular the Center for Condensed Matter Theory and Materials Reseach Center, the Department of Science and Technology, India, the Materials Research Society of India, and the Karnatake State Center for Science and Technology. We would also like to thank the staff and students of Materials Research Center, Indian

  12. Plastic Instability in Amorphous Selenium near its Glass Transition Temperature

    SciTech Connect

    Su, Caijun; Lamanna Jr, James; Gao, Yanfei; Oliver, Warren C.; Pharr, George M

    2010-01-01

    Deformation behavior of amorphous selenium near its glass transition temperature (31 C) has been investigated by uniaxial compression and nanoindentation creep tests. Cylindrical specimens compressed at high temperatures and low strain rates deform into drum-like shape, while tests at low temperatures and high strain rates lead to fragmentation. These results agree nicely with the stress exponent and kinetic activation parameters extracted from the nanoindentation creep tests by using a similarity analysis. The dependence of deformation modes on temperature and strain rate is understood as a consequence of material instability and strain localization in the rate-dependent solids.

  13. Experimental investigation of Rayleigh Taylor instability in elastic-plastic materials

    NASA Astrophysics Data System (ADS)

    Haley, Aaron Alan; Banerjee, Arindam

    2010-11-01

    The interface of an elastic-plastic plate accelerated by a fluid of lower density is Rayleigh Taylor (RT) unstable, the growth being mitigated by the mechanical strength of the plate. The instability is observed when metal plates are accelerated by high explosives, in explosive welding, and in volcanic island formation due to the strength of the inner crust. In contrast to the classical case involving Newtonian fluids, RT instability in accelerated solids is not well understood. The difficulties for constructing a theory for the linear growth phase in solids is essentially due to the character of elastic-plastic constitutive properties which has a nonlinear dependence on the magnitude of the rate of deformation. Experimental investigation of the phenomena is difficult due to the exceedingly small time scales (in high energy density experiments) and large measurement uncertainties of material properties. We performed experiments on our Two-Wheel facility to study the linear stage of the incompressible RT instability in elastic-plastic materials (yogurt) whose properties were well characterized. Rotation of the wheels imparted a constant centrifugal acceleration on the material interface that was cut with a small sinusoidal ripple. The controlled initial conditions and precise acceleration amplitudes are levied to investigate transition from elastic to plastic deformation and allow accurate and detailed measurements of flow properties.

  14. Magnetic Field Generation by the Rayleigh-Taylor Instability in Laser-Driven Planar Plastic Targets

    NASA Astrophysics Data System (ADS)

    Gao, L.; Nilson, P. M.; Igumenschev, I. V.; Hu, S. X.; Davies, J. R.; Stoeckl, C.; Haines, M. G.; Froula, D. H.; Betti, R.; Meyerhofer, D. D.

    2012-09-01

    Magnetic fields generated by the Rayleigh-Taylor instability were measured in laser-accelerated planar foils using ultrafast proton radiography. Thin plastic foils were irradiated with ˜4-kJ, 2.5-ns laser pulses focused to an intensity of ˜1014W/cm2 on the OMEGA EP Laser System. Target modulations were seeded by laser nonuniformities and amplified during target acceleration by the Rayleigh-Taylor instability. The experimental data show the hydrodynamic evolution of the target and MG-level magnetic fields generated in the broken foil. The experimental data are in good agreement with predictions from 2-D magnetohydrodynamic simulations.

  15. Vestibular plasticity following orbital spaceflight: recovery from postflight postural instability

    NASA Technical Reports Server (NTRS)

    Black, F. O.; Paloski, W. H.; Doxey-Gasway, D. D.; Reschke, M. F.

    1995-01-01

    Results of previous studies suggested that the vestibular mediated postural instability observed in astronauts upon return to earth from orbital spaceflight may be exacerbated by an increased weighting of visual inputs for spatial orientation and control of movement. This study was performed to better understand the roles of visual and somatosensory contributions to recovery of normal sensori-motor postural control in returning astronauts. Preflight and postflight, 23 astronaut volunteers were presented randomly with three trials of six sensory organization test (SOT) conditions in the EquiTest system test battery. Sagittal plane center-of-gravity (COG) excursions computed from ground reaction forces were significantly higher on landing day than preflight for those test conditions presenting sway-referenced visual and/or somatosensory orientation cues. The ratio of summed peak-to-peak COG sway amplitudes on the two sway-referenced vision tests (SOTs 3 + 6) compared to the two eyes closed tests (SOTs 2 + 5) was increased on landing day, indicating an increased reliance on visual orientation cues for postural control. The ratio of peak-to-peak COG excursions on sway-referenced surfaces (SOTs 4, 5 & 6) to an earth fixed support surfaces (SOTs 1, 2 & 3) increased even more after landing suggesting primary reliance on somatosensory orientation cues for recovery of postflight postural stability. Readaptation to sway-referenced support surfaces took longer than readaptation to sway-referenced vision. The increased reliance on visual and somatosensory inputs disappeared in all astronauts 4-8 days following return to earth.

  16. Application of critical COD and plastic instability concepts to fracture of shells. [Crack Opening Displacement

    NASA Technical Reports Server (NTRS)

    Erdogan, F.; Ratwani, M.

    1974-01-01

    The paper deals with the initiation, growth, and possible arrest of fracture in shell structures containing initial defects which may be approximated by an isolated part-through crack. The main study is restricted to the structures in which the net section of the shell wall around the defect zone is fully yielded. The problem is solved by using an 8th order shallow shell theory with a conventional plastic strip model to account for the plastic deformations. Using the critical COD or the plastic instability as fracture criterion, the results are applied to the fracture propagation and arrest in shells. The calculated results are then compared with those obtained from the experiments on zircaloy, aluminum, and steel pipes.

  17. Do plastic particles affect microalgal photosynthesis and growth?

    PubMed

    Sjollema, Sascha B; Redondo-Hasselerharm, Paula; Leslie, Heather A; Kraak, Michiel H S; Vethaak, A Dick

    2016-01-01

    The unbridled increase in plastic pollution of the world's oceans raises concerns about potential effects these materials may have on microalgae, which are primary producers at the basis of the food chain and a major global source of oxygen. Our current understanding about the potential modes and mechanisms of toxic action that plastic particles exert on microalgae is extremely limited. How effects might vary with particle size and the physico-chemical properties of the specific plastic material in question are equally unelucidated, but may hold clues to how toxicity, if observed, is exerted. In this study we selected polystyrene particles, both negatively charged and uncharged, and three different sizes (0.05, 0.5 and 6μm) for testing the effects of size and material properties. Microalgae were exposed to different polystyrene particle sizes and surface charges for 72h. Effects on microalgal photosynthesis and growth were determined by pulse amplitude modulation fluorometry and flow cytometry, respectively. None of the treatments tested in these experiments had an effect on microalgal photosynthesis. Microalgal growth was negatively affected (up to 45%) by uncharged polystyrene particles, but only at high concentrations (250mg/L). Additionally, these adverse effects were demonstrated to increase with decreasing particle size. PMID:26675372

  18. Experimental and numerical study of plastic shear instability under high-speed loading conditions

    SciTech Connect

    Sokovikov, Mikhail E-mail: naimark@icmm.ru; Chudinov, Vasiliy E-mail: naimark@icmm.ru; Bilalov, Dmitry E-mail: naimark@icmm.ru; Oborin, Vladimir E-mail: naimark@icmm.ru; Uvarov, Sergey E-mail: naimark@icmm.ru; Plekhov, Oleg E-mail: naimark@icmm.ru; Terekhina, Alena E-mail: naimark@icmm.ru; Naimark, Oleg E-mail: naimark@icmm.ru

    2014-11-14

    The behavior of specimens dynamically loaded during the split Hopkinson (Kolsky) bar tests in a regime close to simple shear conditions was studied. The lateral surface of the specimens was investigated in a real-time mode with the aid of a high-speed infra-red camera CEDIP Silver 450M. The temperature field distribution obtained at different time made it possible to trace the evolution of plastic strain localization. The process of target perforation involving plug formation and ejection was examined using a high-speed infra-red camera and a VISAR velocity measurement system. The microstructure of tested specimens was analyzed using an optical interferometer-profilometer and a scanning electron microscope. The development of plastic shear instability regions has been simulated numerically.

  19. An elastic-plastic finite element analysis of crack initiation, stable crack growth, and instability

    NASA Technical Reports Server (NTRS)

    Newman, J. C., Jr.

    1984-01-01

    Studies have been conducted to develop efficient techniques to simulate crack extension and to examine various local and global fracture criteria. Of the considered criteria, the crack-tip-opening angle (CTOA) or displacement (CTOD) at a specified distance from the crack tip was shown to be most suited for modeling stable crack growth and instability during the fracture process. The results obtained in a number of studies show the necessity for studying different crack configurations when assessing the validity of any fracture criteria. One of the objectives of the present investigation is related to a critical evaluation of the CTOD growth criterion using an elastic-plastic finite element analysis under monotonic loading to failure. The analysis was found to predict three stages of crack growth behavior under monotonic loading to failure. Calculated CTOD values agreed well with experimental values for crack growth initiation.

  20. Projecting low-dimensional chaos from spatiotemporal dynamics in a model for plastic instability

    NASA Astrophysics Data System (ADS)

    Sarmah, Ritupan; Ananthakrishna, G.

    2012-11-01

    We investigate the possibility of projecting low-dimensional chaos from spatiotemporal dynamics of a model for a kind of plastic instability observed under constant strain rate deformation conditions. We first discuss the relationship between the spatiotemporal patterns of the model reflected in the nature of dislocation bands and the nature of stress serrations. We show that at low applied strain rates, there is a one-to-one correspondence with the randomly nucleated isolated bursts of mobile dislocation density and the stress drops. We then show that the model equations are spatiotemporally chaotic by demonstrating the number of positive Lyapunov exponents and Lyapunov dimension scale with the system size at low and high strain rates. Using a modified algorithm for calculating correlation dimension density, we show that the stress-strain signals at low applied strain rates corresponding to spatially uncorrelated dislocation bands exhibit features of low-dimensional chaos. This is made quantitative by demonstrating that the model equations can be approximately reduced to space-independent model equations for the average dislocation densities, which is known to be low-dimensionally chaotic. However, the scaling regime for the correlation dimension shrinks with increasing applied strain rate due to increasing propensity for propagation of the dislocation bands.

  1. Projecting low-dimensional chaos from spatiotemporal dynamics in a model for plastic instability.

    PubMed

    Sarmah, Ritupan; Ananthakrishna, G

    2012-11-01

    We investigate the possibility of projecting low-dimensional chaos from spatiotemporal dynamics of a model for a kind of plastic instability observed under constant strain rate deformation conditions. We first discuss the relationship between the spatiotemporal patterns of the model reflected in the nature of dislocation bands and the nature of stress serrations. We show that at low applied strain rates, there is a one-to-one correspondence with the randomly nucleated isolated bursts of mobile dislocation density and the stress drops. We then show that the model equations are spatiotemporally chaotic by demonstrating the number of positive Lyapunov exponents and Lyapunov dimension scale with the system size at low and high strain rates. Using a modified algorithm for calculating correlation dimension density, we show that the stress-strain signals at low applied strain rates corresponding to spatially uncorrelated dislocation bands exhibit features of low-dimensional chaos. This is made quantitative by demonstrating that the model equations can be approximately reduced to space-independent model equations for the average dislocation densities, which is known to be low-dimensionally chaotic. However, the scaling regime for the correlation dimension shrinks with increasing applied strain rate due to increasing propensity for propagation of the dislocation bands. PMID:23214858

  2. Plastic Instability in Complex Strain Paths Predicted by Advanced Constitutive Equations

    NASA Astrophysics Data System (ADS)

    Butuc, Marilena C.; Barlat, Frédéric; Gracio, José J.; Vincze, Gabriela

    2011-08-01

    The present paper aims at predicting plastic instabilities under complex loading histories using an advanced sheet metal forming limit model. The onset of localized necking is computed using the Marciniak-Kuczinsky (MK) analysis [1] with a physically-based hardening model and the phenomenological anisotropic yield criterion Yld2000-2d [2]. The hardening model accounts for anisotropic work-hardening induced by the microstructural evolution at large strains, which was proposed by Teodosiu and Hu [3]. Simulations are carried out for linear and complex strain paths. Experimentally, two deep-drawing quality sheet metals are selected: a bake-hardening steel (BH) and a DC06 steel sheet. The validity of the model is assessed by comparing the predicted and experimental forming limits. The remarkable accuracy of the developed software to predict the forming limits under linear and non-linear strain path is obviously due to the performance of the advanced constitutive equations to describe with great detail the material behavior. The effect of strain-induced anisotropy on formability evolution under strain path changes, as predicted by the microstructural hardening model, is particularly well captured by the model.

  3. Using plastic instability to validate and test the strength law of a material under pressure

    NASA Astrophysics Data System (ADS)

    Bolis, Cyril; Counilh, Denis; Savale, Brice

    2015-09-01

    In dynamical experiments (pressures higher than 10 GPa, strain rate around 104-106 s-1), metals are classically described using an equation of state and a strength law which is usually set using data from compression or traction tests at low pressure (few MPa) and low strain rates (less than 103 s-1). In consequence, it needs to be extrapolated during dynamical experiments. Classical shock experiments do not allow a fine validation of the stress law due to the interaction with the equation of state. To achieve this aim, we propose to use a dedicated experiment. We started from the works of Barnes et al. (1974 and 1980) where plastic instabilities initiated by a sinusoidal perturbation at the surface of the metal develop with the pressure. We adapted this principle to a new shape of initial perturbation and realized several experiments. We will present the setup and its use on a simple material: gold. We will detail how the interpretation of the experiments, coupled with previous characterization experiments helps us to test the strength lax of this material at high pressure and high strain rate.

  4. How do hydrodynamic instabilities affect 3D transport in geophysical vortices?

    NASA Astrophysics Data System (ADS)

    Wang, Peng; Özgökmen, Tamay M.

    2015-03-01

    Three-dimensional (3D) transport within geophysical vortices (e.g. ocean eddies) is important in understanding processes at a variety of scales, ranging from plankton production to climate variability. 3D transport can be affected by hydrodynamic instabilities of geophysical vortices; however, how the instabilities affecting 3D transport is not clear. Focusing on barotropic, inertial and 3D instabilities, we investigate the joint impacts of instabilities on 3D transport by using analytical methods and direct numerical simulations. We discover for the first time that material can be exchanged through 3D pathways which link a family of vortices generated by the instabilities in a single, initially unstable vortex. We also show that instabilities can increase the magnitude of vertical velocity, mixing rate and vertical material exchange. Besides, we find that instabilities can cause the kinetic energy wavenumber spectrum to have a power-law regime different than the classic regimes of k - 5 / 3 and k-3, and propose a new energy spectrum to interpret the non-classic regime.

  5. Affected chromosome homeostasis and genomic instability of clonal yeast cultures.

    PubMed

    Adamczyk, Jagoda; Deregowska, Anna; Panek, Anita; Golec, Ewelina; Lewinska, Anna; Wnuk, Maciej

    2016-05-01

    Yeast cells originating from one single colony are considered genotypically and phenotypically identical. However, taking into account the cellular heterogeneity, it seems also important to monitor cell-to-cell variations within a clone population. In the present study, a comprehensive yeast karyotype screening was conducted using single chromosome comet assay. Chromosome-dependent and mutation-dependent changes in DNA (DNA with breaks or with abnormal replication intermediates) were studied using both single-gene deletion haploid mutants (bub1, bub2, mad1, tel1, rad1 and tor1) and diploid cells lacking one active gene of interest, namely BUB1/bub1, BUB2/bub2, MAD1/mad1, TEL1/tel1, RAD1/rad1 and TOR1/tor1 involved in the control of cell cycle progression, DNA repair and the regulation of longevity. Increased chromosome fragility and replication stress-mediated chromosome abnormalities were correlated with elevated incidence of genomic instability, namely aneuploid events-disomies, monosomies and to a lesser extent trisomies as judged by in situ comparative genomic hybridization (CGH). The tor1 longevity mutant with relatively balanced chromosome homeostasis was found the most genomically stable among analyzed mutants. During clonal yeast culture, spontaneously formed abnormal chromosome structures may stimulate changes in the ploidy state and, in turn, promote genomic heterogeneity. These alterations may be more accented in selected mutated genetic backgrounds, namely in yeast cells deficient in proper cell cycle regulation and DNA repair. PMID:26581629

  6. Richtmyer-Meshkov instability for elastic-plastic solids in converging geometries

    NASA Astrophysics Data System (ADS)

    López Ortega, A.; Lombardini, M.; Barton, P. T.; Pullin, D. I.; Meiron, D. I.

    2015-03-01

    We present a detailed study of the interface instability that develops at the boundary between a shell of elastic-plastic material and a cylindrical core of confined gas during the inbound implosive motion generated by a shock-wave. The main instability in this configuration is the so-called Richtmyer-Meshkov instability that arises when the shock wave crosses the material interface. Secondary instabilities, such as Rayleigh-Taylor, due to the acceleration of the interface, and Kelvin-Helmholtz, due to slip between solid and fluid, arise as the motion progresses. The reflection of the shock wave at the axis and its second interaction with the material interface as the shock moves outbound, commonly known as re-shock, results in a second Richtmyer-Meshkov instability that potentially increases the growth rate of interface perturbations, resulting in the formation of a mixing zone typical of fluid-fluid configurations and the loss of the initial perturbation length scales. The study of this problem is of interest for achieving stable inertial confinement fusion reactions but its complexity and the material conditions produced by the implosion close to the axis prove to be challenging for both experimental and numerical approaches. In this paper, we attempt to circumvent some of the difficulties associated with a classical numerical treatment of this problem, such as element inversion in Lagrangian methods or failure to maintain the relationship between the determinant of the deformation tensor and the density in Eulerian approaches, and to provide a description of the different events that occur during the motion of the interface. For this purpose, a multi-material numerical solver for evolving in time the equations of motion for solid and fluid media in an Eulerian formalism has been implemented in a Cartesian grid. Equations of state are derived using thermodynamically consistent hyperelastic relations between internal energy and stresses. The resolution required

  7. Do Polyethylene Plastic Covers Affect Smoke Emissions from Debris Piles?

    NASA Astrophysics Data System (ADS)

    Weise, D. R.; Jung, H.; Cocker, D.; Hosseini, E.; Li, Q.; Shrivastava, M.; McCorison, M.

    2010-12-01

    Shrubs and small diameter trees exist in the understories of many western forests. They are important from an ecological perspective; however, this vegetation also presents a potential hazard as “ladder fuels” or as a heat source to damage the overstory during prescribed burns. Cutting and piling of this material to burn under safe conditions is a common silvicultural practice. To improve ignition success of the piled debris, polyethylene plastic is often used to cover a portion of the pile. While burning of piled forest debris is an acceptable practice in southern California from an air quality perspective, inclusion of plastic in the piles changes these debris piles to rubbish piles which should not be burned. With support from the four National Forests in southern California, we conducted a laboratory experiment to determine if the presence of polyethylene plastic in a pile of burning wood changed the smoke emissions. Debris piles in southern California include wood and foliage from common forest trees such as sugar and ponderosa pines, white fir, incense cedar, and California black oak and shrubs such as ceanothus and manzanita in addition to forest floor material and dirt. Manzanita wood was used to represent the debris pile in order to control the effects of fuel bed composition. The mass of polyethylene plastic incorporated into the pile was 0, 0.25 and 2.5% of the wood mass—a range representative of field conditions. Measured emissions included NOx, CO, CO2, SO2, polycyclic and light hydrocarbons, carbonyls, particulate matter (5 to 560 nm), elemental and organic carbon. The presence of polyethylene did not alter the emissions composition from this experiment.

  8. Magnetic Field Generation by the Nonlinear Rayleigh--Taylor Instability in Laser-Driven Planar Plastic Targets

    NASA Astrophysics Data System (ADS)

    Gao, L.; Igumenshchev, I. V.; Hu, S. X.; Stoeckl, C.; Froula, D. H.; Nilson, P. M.; Davies, J. R.; Betti, R.; Meyerhofer, D. D.; Haines, M. G.

    2012-10-01

    Magnetic field generation during the nonlinear phase of the Rayleigh--Taylor (RT) instability in an ablatively driven plasma using ultrafast laser-driven proton radiography has been measured. Thin plastic foils were irradiated with ˜4-kJ, 2.5-ns laser pulses focused to an intensity of ˜10^14 W/cm^2 on the OMEGA EP Laser System. Target modulations were seeded by laser nonuniformities and amplified during target acceleration by the RT instability. The experimental data show the hydrodynamic evolution of the target and MG-level magnetic fields generated in the broken foil. The experimental data are in good agreement with predictions from 2-D magnetohydrodynamic simulations. This work was supported by the U.S. Department of Energy Office of Inertial Confinement Fusion under Cooperative Agreement No. DE-FC52-08NA28302.

  9. Adhesion-induced instabilities in elastic and elastic-plastic contacts during single and repetitive normal loading

    NASA Astrophysics Data System (ADS)

    Song, Z.; Komvopoulos, K.

    2011-04-01

    Adhesive interaction in spherical contacts was modeled with the Lennard-Jones (L-J) potential. Elastic adhesive contact was analyzed by the equivalent system of a rigid sphere with reduced radius of curvature and a half-space of effective elastic modulus. The critical gap at the instant of abrupt surface contact (jump-in) and separation (jump-out) was determined from the deformed surface profile of the elastic half-space and geometrical relationships. A finite element model of a rigid sphere and an elastic-plastic half-space was used to examine elastic-plastic adhesive contact. Surface adhesion was modeled by nonlinear springs with a force-displacement relationship governed by the L-J potential. The evolution of the interfacial force and the central gap distance as well as the occurrence of jump-in and jump-out instabilities were investigated in terms of the Tabor parameter, plasticity parameter, and dimensionless maximum normal displacement. The force-displacement response due to several approach-retraction cycles was interpreted in the context of elastic and plastic shakedown behaviors using dimensionless parameters.

  10. CB1 receptor affects cortical plasticity and response to physiotherapy in multiple sclerosis

    PubMed Central

    Mori, Francesco; Ljoka, Concetta; Nicoletti, Carolina G.; Kusayanagi, Hajime; Buttari, Fabio; Giordani, Laura; Rossi, Silvia; Foti, Calogero

    2014-01-01

    Objectives: Therapeutic effects of physical therapy in neurologic disorders mostly rely on the promotion of use-dependent synaptic plasticity in damaged neuronal circuits. Genetic differences affecting the efficiency of synaptic plasticity mechanisms could explain why some patients do not respond adequately to the treatment. It is known that physical exercise activates the endocannabinoid system and that stimulation of cannabinoid CB1 receptors (CB1Rs) promotes synaptic plasticity in both rodents and humans. We thus tested whether CB1R genetic variants affect responsiveness to exercise therapy. Methods: We evaluated the effect of a genetic variant of the CB1R associated with reduced receptor expression (patients with long AAT trinucleotide short tandem repeats in the CNR1 gene) on long-term potentiation (LTP)–like cortical plasticity induced by transcranial magnetic theta burst stimulation (TBS) of the motor cortex and, in parallel, on clinical response to exercise therapy in patients with multiple sclerosis. Results: We found that patients with long AAT CNR1 repeats do not express TBS-induced LTP-like cortical plasticity and show poor clinical benefit after exercise therapy. Conclusions: Our results provide the first evidence that genetic differences within the CB1R may influence clinical responses to exercise therapy, and they strengthen the hypothesis that CB1Rs are involved in the regulation of synaptic plasticity and in the control of spasticity in humans. This information might be of great relevance for patient stratification and personalized rehabilitation treatment programs. PMID:25520956

  11. Affective instability and suicidal ideation and behavior in patients with borderline personality disorder.

    PubMed

    Links, Paul S; Eynan, Rahel; Heisel, Marnin J; Barr, Aiala; Korzekwa, Marilyn; McMain, Shelley; Ball, Jeffrey S

    2007-02-01

    This study employed an Experience Sampling Methodology (ESM) to test whether various elements of affective instability can predict future suicide ideation in patients with borderline personality disorder (BPD) and a history of recurrent suicidal behavior. Eighty-two individuals with BPD and a history of recurrent suicidal behavior were followed prospectively for one month during which time they recorded their current mood states, 6 times daily over three weeks. Accounting for a set of robust suicide risk factors in multiple regression analyses, only negative mood intensity was significantly related to intensity of self-reported suicide ideation and to number of suicidal behaviors over the past year. Other elements of affective instability examined (e.g., mood amplitude, dyscontrol, and reactivity) were not associated with future suicide ideation or with recent suicidal behavior. Affective instability in patients with BPD is highly variable from one individual to another and is characterized by high levels of intense negative mood. These negative mood states, versus other aspects of mood variability, seem to be more closely tied to the occurrence of suicidal ideation and behavior. PMID:17373891

  12. The use of COD and plastic instability in crack propagation and arrest in shells

    NASA Technical Reports Server (NTRS)

    Erdogan, F.; Ratwani, M.

    1974-01-01

    The initiation, growth, and possible arrest of fracture in cylindrical shells containing initial defects are dealt with. For those defects which may be approximated by a part-through semi-elliptic surface crack which is sufficiently shallow so that part of the net ligament in the plane of the crack is still elastic, the existing flat plate solution is modified to take into account the shell curvature effect as well as the effect of the thickness and the small scale plastic deformations. The problem of large defects is then considered under the assumptions that the defect may be approximated by a relatively deep meridional part-through surface crack and the net ligament through the shell wall is fully yielded. The results given are based on an 8th order bending theory of shallow shells using a conventional plastic strip model to account for the plastic deformations around the crack border.

  13. Tensile elastic properties of 18:8 chromium-nickel steel as affected by plastic deformation

    NASA Technical Reports Server (NTRS)

    Mcadam, D J; Mebs, R W

    1939-01-01

    The relationship between stress and strain, and between stress and permanent set, for 18:8 alloy as affected by prior plastic deformation is discussed. Hysteresis and creep and their effects on the stress-strain and stress-set curves are also considered, as well as the influence of duration of the rest interval after cold work and the influence of plastic deformation on proof stresses, on the modulus of elasticity at zero stress, and on the curvature of the stress-strain line. A constant (c sub 1) is suggested to represent the variation of the modulus of elasticity with stress.

  14. Specificity of Affective Instability in Patients With Borderline Personality Disorder Compared to Posttraumatic Stress Disorder, Bulimia Nervosa, and Healthy Controls

    PubMed Central

    Santangelo, Philip; Mussgay, Lutz; Sawitzki, Günther; Trull, Timothy J.; Reinhard, Iris; Steil, Regina; Klein, Christoph; Bohus, Martin; Ebner-Priemer, Ulrich W.

    2014-01-01

    Affective instability is a core feature of borderline personality disorder (BPD). The use of advanced assessment methodologies and appropriate statistical analyses has led to consistent findings that indicate a heightened instability in patients with BPD compared with healthy controls. However, few studies have investigated the specificity of affective instability among patients with BPD with regard to relevant clinical control groups. In this study, 43 patients with BPD, 28 patients with posttraumatic stress disorder (PTSD), 20 patients with bulimia nervosa (BN), and 28 healthy controls carried e-diaries for 24 hours and were prompted to rate their momentary affective states approximately every 15 minutes while awake. To quantify instability, we used 3 state-of-the-art indices: multilevel models for squared successive differences (SSDs), multilevel models for probability of acute changes (PACs), and aggregated point-by-point changes (APPCs). Patients with BPD displayed heightened affective instability for emotional valence and distress compared with healthy controls, regardless of the specific instability indices. These results directly replicate earlier studies. However, affective instability did not seem to be specific to patients with BPD. With regard to SSDs, PACs, and APPCs, patients with PTSD or BN showed a similar heightened instability of affect (emotional valence and distress) to that of patients with BPD. Our results give raise to the discussion if affective instability is a transdiagnostic or a disorder-specific mechanism. Current evidence cannot answer this question, but investigating psychopathological mechanisms in everyday life across disorders is a promising approach to enhance validity and specificity of mental health diagnoses. PMID:24661176

  15. A novel parametric instability of propagating critical layer affecting the laser longitudinal envelope

    NASA Astrophysics Data System (ADS)

    Sahai, Aakash

    2015-11-01

    A parametric instability that affects the longitudinal envelope of a laser pulse interacting with a propagating critical layer is presented [Sahai, PoP 21,056707, 2014; Sahai, arXiv:1411.2401, 2014]. It is shown that non-linear mixing between the incident and reflected laser pulse from a propagating critical layer electron compression results in a beat-wave with a complete modulation of the incident wave envelope. This beat-wave modulates the velocity of the propagating critical layer, resulting in a new Doppler frequency which creates a second beat-wave, further modulating the laser envelope. The frequency spread of the laser envelope grows in time resulting in a large spectral spread of the laser pulse envelope. The velocity of the propagating critical layer acceleration structure is correspondingly modulated as is the space-charge potential. Thus, the ions that are accelerated off the potential have a large energy spread. Since, the growth rate of this instability depends upon the acceleration structure velocity, longer pulses are unfavorable for accelerating ions to higher energies with a narrow energy spread. This instability is also relevant to laser-driven fusion and laser hole-boring based fast-ignition but due to much smaller velocities, its effect is mitigated.

  16. Boudinage as a material instability of elasto-visco-plastic rocks

    NASA Astrophysics Data System (ADS)

    Peters, Max; Veveakis, Manolis; Poulet, Thomas; Karrech, Ali; Herwegh, Marco; Regenauer-Lieb, Klaus

    2015-09-01

    Pinch-and-swell structures are commonly interpreted to evolve out of viscosity contrasts, which are induced by geometric interactions and material imperfections. From materials science an additional localization phenomenon is well established, where localization emerges out of steady state for critical material parameters and/or loading rates. Here we investigate the conditions under which this second type of instabilities prevails and whether geological materials necessarily require a trigger by imperfections in order to generate instability. We focus on imperfections in terms of grain size variations embedded in a deformation environment controlled by thermo-mechanical feedbacks. We introduce a random distribution of grain sizes over two orders of magnitude in a central layer embedded in a matrix with a diffusion creep rheology. The rheology of the layer evolves with dislocation and diffusion creep as end-member deformation mechanisms. Applying pure shear extension, the 3-layer model is subjected to natural deformation conditions. The central layer quickly establishes a viscous steady state as a natural response of the system due to relaxation and energy optimization. Upon continued loading, localization then intriguingly arises out of a homogeneous state. We present an analysis which confirms that this type of instability is indeed physically admissible. Using vibration analysis, we verify the robustness of the numerical solution by first identifying the natural mode shapes and frequencies of the simulated structure and material parameters, including geometric imperfections. In a second step, the eigenmodes are perturbed and superposed to the initial conditions. We conclude that this pattern of perturbations guides the onset of strain localization. Boudinage can therefore be seen both as a geometric problem and/or a material bifurcation, which evolves out of homogeneous state. The latter class offers the great possibility of extracting fundamental material

  17. A Mixed Model to Disentangle Variance and Serial Autocorrelation in Affective Instability Using Ecological Momentary Assessment Data.

    PubMed

    Vansteelandt, Kristof; Verbeke, Geert

    2016-01-01

    Affective instability, the tendency to experience emotions that fluctuate frequently and intensively over time, is a core feature of several mental disorders including borderline personality disorder. Currently, affect is often measured with Ecological Momentary Assessment protocols, which yield the possibility to quantify the instability of affect over time. A number of linear mixed models are proposed to examine (diagnostic) group differences in affective instability. The models contribute to the existing literature by estimating simultaneously both the variance and serial dependency component of affective instability when observations are unequally spaced in time with the serial autocorrelation (or emotional inertia) declining as a function of the time interval between observations. In addition, the models can eliminate systematic trends, take between subject differences into account and test for (diagnostic) group differences in serial autocorrelation, short-term as well as long-term affective variability. The usefulness of the models is illustrated in a study on diagnostic group differences in affective instability in the domain of eating disorders. Limitations of the model are that they pertain to group (and not individual) differences and do not focus explicitly on circadian rhythms or cycles in affect. PMID:27191204

  18. Factors Affecting Return to Baseline Function at 6 months Following Anterior Shoulder Instability Surgery

    PubMed Central

    Hettrich, Carolyn M.; Buckwalter, Joseph; Wolf, Brian R.; Bollier, Matthew; MOON, Shoulder Group; Glass, Natalie

    2016-01-01

    Objectives: Pre-operative and surgical factors related to early return to baseline function after anterior shoulder instability surgery are not clear. This study was designed to determine the pre-operative and operative factors affecting return to baseline function at 6 months following anterior shoulder instability surgery. Identifying these factors will help surgeons establish expectations for functional return post-operatively. Methods: The Multicenter Orthopaedic Outcomes Network (MOON) shoulder group enrolled patients undergoing surgery for shoulder instability from 16 sites throughout the United States. Initial demographic data and validated, patient-oriented outcomes questionnaires were collected along with the physicians documented initial physical exam, treatment, surgical findings and surgical techniques used at the time of surgery. At the 6-month follow up visit, range of motion (ROM) and strength measurement of the operative shoulder were collected and compared to pre-operative measurement. Return to baseline was defined as return to within -10° ROM and full strength at the 6 month physical exam. Continuous and categorical data were analyzed using student t-tests and chi-square tests, respectively. The Kruskal-Wallis/Wilcoxin tests were used to compare groups that were not normally distributed. Factors reaching significance in a univariate analysis were then applied in a multivariable model. Significance was set a p<0.05. Results: A total of 338 patients with history of surgical intervention for anterior instability of the shoulder were identified. 278 patients had complete pre- and post-surgical range of motion and strength measurements. 138 (50%) patients (139 shoulders) returned to baseline and 133 (50%) patients did not return to baseline. Univariate analysis identified age (p=0.0013), Beighton score (p=0.0004), SF-36 general health (p=0.0017), WOSI (p=0.0250), and duration of symptoms (p=0.0046) as significant factors. When these factors were

  19. Plastic components affect the activation of the aryl hydrocarbon and the androgen receptor.

    PubMed

    Krüger, Tanja; Long, Manhai; Bonefeld-Jørgensen, Eva C

    2008-04-18

    Phenols and plasticizers are widely used in the plastic industry, in food packaging and to impart softness and flexibility to normally rigid plastic medical devices and children's toys. The effects on the aryl hydrocarbon receptor (AhR) and the androgen receptor (AR) were assessed using luciferase reporter gene assays of the following compounds: bisphenol A (BPA), 4-n-nonylphenol (nNP), 4-tert-octylphenol (tOP), bis(2-ethylhexyl) phthalate (DEHP), di-isononyl phthalate (DINP), diisodecyl phthalate (DIDP), di-n-octyl phthalate (DNOP), dibutyl phthalate (DBP), benzyl butyl phthalate (BBP), 4-chloro-3-methylphenol (CMP), 2-phenylphenol (2-PP), 2,4-dichlorophenol (DCP), resorcinol and bis(2-ethylhexyl) adipate (DEHA). Furthermore, a mixture of selected compounds was tested at the no-observed-effect concentration (NOEC), the low-observed-effect concentration (LOEC) and the half-maximum-effect/inhibitory concentration (EC50/IC50) of the single chemicals. Both receptors were affected by BPA, nNP, BBP, CMP, DCP and resorcinol whereas DEHP, DIDP and DBP affected only the AhR and tOP and 2-PP antagonised the AR activity. The mixture was composed of 6 compounds, of which one compound weakly induced the AhR but all compounds antagonized the AR activation. Using the concentration addition principle additive effects were observed at the NOEC, LOEC and EC50/IC50 for both receptors. Our in vitro data suggest that the effect of a mixture depends on the concentration, character, potency and composition of the single mixture compounds and that also the combined effects of the compounds should be taken into consideration for risk assessment of human health. PMID:18294747

  20. Pushing the Limits: Cognitive, Affective, and Neural Plasticity Revealed by an Intensive Multifaceted Intervention.

    PubMed

    Mrazek, Michael D; Mooneyham, Benjamin W; Mrazek, Kaita L; Schooler, Jonathan W

    2016-01-01

    Scientific understanding of how much the adult brain can be shaped by experience requires examination of how multiple influences combine to elicit cognitive, affective, and neural plasticity. Using an intensive multifaceted intervention, we discovered that substantial and enduring improvements can occur in parallel across multiple cognitive and neuroimaging measures in healthy young adults. The intervention elicited substantial improvements in physical health, working memory, standardized test performance, mood, self-esteem, self-efficacy, mindfulness, and life satisfaction. Improvements in mindfulness were associated with increased degree centrality of the insula, greater functional connectivity between insula and somatosensory cortex, and reduced functional connectivity between posterior cingulate cortex (PCC) and somatosensory cortex. Improvements in working memory and reading comprehension were associated with increased degree centrality of a region within the middle temporal gyrus (MTG) that was extensively and predominately integrated with the executive control network. The scope and magnitude of the observed improvements represent the most extensive demonstration to date of the considerable human capacity for change. These findings point to higher limits for rapid and concurrent cognitive, affective, and neural plasticity than is widely assumed. PMID:27047361

  1. Pushing the Limits: Cognitive, Affective, and Neural Plasticity Revealed by an Intensive Multifaceted Intervention

    PubMed Central

    Mrazek, Michael D.; Mooneyham, Benjamin W.; Mrazek, Kaita L.; Schooler, Jonathan W.

    2016-01-01

    Scientific understanding of how much the adult brain can be shaped by experience requires examination of how multiple influences combine to elicit cognitive, affective, and neural plasticity. Using an intensive multifaceted intervention, we discovered that substantial and enduring improvements can occur in parallel across multiple cognitive and neuroimaging measures in healthy young adults. The intervention elicited substantial improvements in physical health, working memory, standardized test performance, mood, self-esteem, self-efficacy, mindfulness, and life satisfaction. Improvements in mindfulness were associated with increased degree centrality of the insula, greater functional connectivity between insula and somatosensory cortex, and reduced functional connectivity between posterior cingulate cortex (PCC) and somatosensory cortex. Improvements in working memory and reading comprehension were associated with increased degree centrality of a region within the middle temporal gyrus (MTG) that was extensively and predominately integrated with the executive control network. The scope and magnitude of the observed improvements represent the most extensive demonstration to date of the considerable human capacity for change. These findings point to higher limits for rapid and concurrent cognitive, affective, and neural plasticity than is widely assumed. PMID:27047361

  2. Analysis of Affective Instability in Ecological Momentary Assessment: Indices Using Successive Difference and Group Comparison via Multilevel Modeling

    ERIC Educational Resources Information Center

    Jahng, Seungmin; Wood, Phillip K.; Trull, Timothy J.

    2008-01-01

    Temporal instability of affect is a defining characteristic of psychological disorders such as borderline personality disorder (BPD) and mood cycling disorders. Ecological momentary assessment (EMA) enables researchers to directly assess such frequent and extreme fluctuations over time. The authors examined 4 operationalizations of such temporal…

  3. ERK Pathway Activation Bidirectionally Affects Visual Recognition Memory and Synaptic Plasticity in the Perirhinal Cortex

    PubMed Central

    Silingardi, Davide; Angelucci, Andrea; De Pasquale, Roberto; Borsotti, Marco; Squitieri, Giovanni; Brambilla, Riccardo; Putignano, Elena; Pizzorusso, Tommaso; Berardi, Nicoletta

    2011-01-01

    ERK 1,2 pathway mediates experience-dependent gene transcription in neurons and several studies have identified its pivotal role in experience-dependent synaptic plasticity and in forms of long term memory involving hippocampus, amygdala, or striatum. The perirhinal cortex (PRHC) plays an essential role in familiarity-based object recognition memory. It is still unknown whether ERK activation in PRHC is necessary for recognition memory consolidation. Most important, it is unknown whether by modulating the gain of the ERK pathway it is possible to bidirectionally affect visual recognition memory and PRHC synaptic plasticity. We have first pharmacologically blocked ERK activation in the PRHC of adult mice and found that this was sufficient to impair long term recognition memory in a familiarity-based task, the object recognition task (ORT). We have then tested performance in the ORT in Ras-GRF1 knock-out (KO) mice, which exhibit a reduced activation of ERK by neuronal activity, and in ERK1 KO mice, which have an increased activation of ERK2 and exhibit enhanced striatal plasticity and striatal mediated memory. We found that Ras-GRF1 KO mice have normal short term memory but display a long term memory deficit; memory reconsolidation is also impaired. On the contrary, ERK1 KO mice exhibit a better performance than WT mice at 72 h retention interval, suggesting a longer lasting recognition memory. In parallel with behavioral data, LTD was strongly reduced and LTP was significantly smaller in PRHC slices from Ras-GRF1 KO than in WT mice while enhanced LTP and LTD were found in PRHC slices from ERK1 KO mice. PMID:22232579

  4. Plasticity and epistasis strongly affect bacterial fitness after losing multiple metabolic genes.

    PubMed

    D'Souza, Glen; Waschina, Silvio; Kaleta, Christoph; Kost, Christian

    2015-05-01

    Many bacterial lineages lack seemingly essential metabolic genes. Previous work suggested selective benefits could drive the loss of biosynthetic functions from bacterial genomes when the corresponding metabolites are sufficiently available in the environment. However, the factors that govern this "genome streamlining" remain poorly understood. Here we determine the effect of plasticity and epistasis on the fitness of Escherichia coli genotypes from whose genome biosynthetic genes for one, two, or three different amino acids have been deleted. Competitive fitness experiments between auxotrophic mutants and prototrophic wild-type cells in one of two carbon environments revealed that plasticity and epistasis strongly affected the mutants' fitness individually and interactively. Positive and negative epistatic interactions were prevalent, yet on average cancelled each other out. Moreover, epistasis correlated negatively with the expected effects of combined auxotrophy-causing mutations, thus producing a pattern of diminishing returns. Moreover, computationally analyzing 1,432 eubacterial metabolic networks revealed that most pairs of auxotrophies co-occurred significantly more often than expected by chance, suggesting epistatic interactions and/or environmental factors favored these combinations. Our results demonstrate that both the genetic background and environmental conditions determine the adaptive value of a loss-of-biochemical-function mutation and that fitness gains decelerate, as more biochemical functions are lost. PMID:25765095

  5. Interplay of model ingredients affecting aggregate shape plasticity in diffusion-limited aggregation

    NASA Astrophysics Data System (ADS)

    Duarte-Neto, P.; Stošić, T.; Stošić, B.; Lessa, R.; Milošević, M. V.

    2014-07-01

    We analyze the combined effect of three ingredients of an aggregation model—surface tension, particle flow and particle source—representing typical characteristics of many aggregation growth processes in nature. Through extensive numerical experiments and for different underlying lattice structures we demonstrate that the location of incoming particles and their preferential direction of flow can significantly affect the resulting general shape of the aggregate, while the surface tension controls the surface roughness. Combining all three ingredients increases the aggregate shape plasticity, yielding a wider spectrum of shapes as compared to earlier works that analyzed these ingredients separately. Our results indicate that the considered combination of effects is fundamental for modeling the polymorphic growth of a wide variety of structures in confined geometries and/or in the presence of external fields, such as rocks, crystals, corals, and biominerals.

  6. Interplay of model ingredients affecting aggregate shape plasticity in diffusion-limited aggregation.

    PubMed

    Duarte-Neto, P; Stošić, T; Stošić, B; Lessa, R; Milošević, M V

    2014-07-01

    We analyze the combined effect of three ingredients of an aggregation model--surface tension, particle flow and particle source--representing typical characteristics of many aggregation growth processes in nature. Through extensive numerical experiments and for different underlying lattice structures we demonstrate that the location of incoming particles and their preferential direction of flow can significantly affect the resulting general shape of the aggregate, while the surface tension controls the surface roughness. Combining all three ingredients increases the aggregate shape plasticity, yielding a wider spectrum of shapes as compared to earlier works that analyzed these ingredients separately. Our results indicate that the considered combination of effects is fundamental for modeling the polymorphic growth of a wide variety of structures in confined geometries and/or in the presence of external fields, such as rocks, crystals, corals, and biominerals. PMID:25122308

  7. Affecting Pseudomonas aeruginosa Phenotypic Plasticity by Quorum Sensing Dysregulation Hampers Pathogenicity in Murine Chronic Lung Infection

    PubMed Central

    Bondí, Roslen; Messina, Marco; De Fino, Ida; Bragonzi, Alessandra; Rampioni, Giordano; Leoni, Livia

    2014-01-01

    In Pseudomonas aeruginosa quorum sensing (QS) activates the production of virulence factors, playing a critical role in pathogenesis. Multiple negative regulators modulate the timing and the extent of the QS response either in the pre-quorum or post-quorum phases of growth. This regulation likely increases P. aeruginosa phenotypic plasticity and population fitness, facilitating colonization of challenging environments such as higher organisms. Accordingly, in addition to the factors required for QS signals synthesis and response, also QS regulators have been proposed as targets for anti-virulence therapies. However, while it is known that P. aeruginosa mutants impaired in QS are attenuated in their pathogenic potential, the effect of mutations causing a dysregulated timing and/or magnitude of the QS response has been poorly investigated so far in animal models of infection. In order to investigate the impact of QS dysregulation on P. aeruginosa pathogenesis in a murine model of lung infection, the QteE and RsaL proteins have been selected as representatives of negative regulators controlling P. aeruginosa QS in the pre- and post-quorum periods, respectively. Results showed that the qteE mutation does not affect P. aeruginosa lethality and ability to establish chronic infection in mice, despite causing a premature QS response and enhanced virulence factors production in test tube cultures compared to the wild type. Conversely, the post-quorum dysregulation caused by the rsaL mutation hampers the establishment of P. aeruginosa chronic lung infection in mice without affecting the mortality rate. On the whole, this study contributes to a better understanding of the impact of QS regulation on P. aeruginosa phenotypic plasticity during the infection process. Possible fallouts of these findings in the anti-virulence therapy field are also discussed. PMID:25420086

  8. The Role of GluK4 in Synaptic Plasticity and Affective Behavior in Mice

    NASA Astrophysics Data System (ADS)

    Catches, Justin Samuel

    Kainate receptors (KARs) are glutamate-gated ion channels that signal through both ionotropic and metabotropic pathways (Contractor et al., 2011). Combinations of five KAR subunits (GluK1-5) form tetrameric receptors with GluK1, GluK2, and GluK3 able to form functional homomeric channels. The high-affinity subunits, GluK4 and GluK5, do not form homomeric channels but modify the properties of heteromeric receptors. Expression of the GluK4 receptor subunit in the forebrain is restricted to the CA3 region of the hippocampus and dentate gyrus regions where KARs modulate synaptic plasticity. In this study, ablation of Grik4, which encodes GluK4, in mice reduced KAR synaptic currents and altered activation properties of postsynaptic receptors but left two forms of presynaptic short-term plasticity intact. Disruption of both Grik4 and Grik5 caused complete loss of the postsynaptic ionotropic KAR current and impaired presynaptic frequency facilitation. Additionally, KAR surface expression was altered at pre- and postsynaptic sites at the MF synapse. Despite the loss of ionotropic signaling, KAR-mediated inhibition of the slow afterhyperpolarization current, which is dependent on metabotropic signaling, was intact in CA3 neurons. Long-term potentiation at the MF-CA3 synapse was reduced, likely through a loss of KAR modulation of excitability of the presynaptic MF axons. Genetic variants in the human GRIK4 gene alter the susceptibility for affective disorders (Bloss and Hunter, 2010). We found that ablation of Grik4 in mice resulted in reduced anxiety and an antidepressant-like phenotype. In the elevated zero-maze, a test for anxiety and risk taking behavior, and in two anxiogenic tests, marble-burying and novelty-induced suppression of feeding, anxiety-like behavior was consistently reduced in knockout animals. In the forced swim, a test of learned helplessness used to determine depression-like behavior, knockout mice demonstrated significantly less immobility suggesting

  9. How Do Hydrodynamic Instabilities Affect 3D Transport in Geophysical Vortices?

    NASA Astrophysics Data System (ADS)

    Wang, P.; Ozgokmen, T. M.

    2014-12-01

    Understanding three-dimensional (3D) transport in ocean eddies is important for processes at a variety of scales, ranging from plankton production to climate variability. It is well known that geophysical vortices are subject to various hydrodynamic instabilities. Yet the influence of these instabilities on 3D material transport in vortex systems is not well investigated. Focusing on barotropic, inertial and 3D instabilities, we analyze these instabilities with normal-mode method, and reproduce their characteristics via highly-resolved numerical simulations using a spectral element Navier-Stokes solver. By comparing the simulation results of stable and unstable vortices, we investigate the joint impacts of instabilities on 3D transport through three major aspects: (i) energy transfer, (ii) overturning transport of the secondary circulation, and (iii) rates of vertical exchange and mixing. It is found that instabilities can enhance local nonlinear interactions and cause the kinetic energy wavenumber spectrum to have slopes between the conventional -5/3 and -3 at inertial ranges. The cascade of a new quantity is proposed to explain these non-conventional slopes. One of our main results is the discovery of material exchange between the central vortex and satellite vortices through 3D pathways, called funnels. These funnels modify the concept of elliptic regions that can trap material when confined to 2D dynamics. Thus, we show that a family of vortices, created by the hydrodynamic instabilities of the initially unstable vortex, can still continue to operate in unity in order to complete the 3D transport in these systems. We also show that flow instabilities can double the magnitude of vertical velocity, increase the rate of vertical exchange by an order of magnitude and enhance mixing rate more than 100%.

  10. Cognitive-affective neural plasticity following active-controlled mindfulness intervention

    PubMed Central

    Allen, Micah; Dietz, Martin; Blair, Karina S.; van Beek, Martijn; Rees, Geraint; Vestergaard-Poulsen, Peter; Lutz, Antoine; Roepstorff, Andreas

    2015-01-01

    Mindfulness meditation is a set of attention-based, regulatory and self-inquiry training regimes. Although the impact of mindfulness meditation training (MT) on self-regulation is well established, the neural mechanisms supporting such plasticity are poorly understood. MT is thought to act on attention through interoceptive salience and attentional control mechanisms, but until now conflicting evidence from behavioral and neural measures has made it difficult to distinguish the role of these mechanisms. To resolve this question we conducted a fully randomized 6-week longitudinal trial of MT, explicitly controlling for cognitive and treatment effects with an active control group. We measured behavioral metacognition and whole-brain Blood Oxygenation Level Dependent (BOLD) signals using functional MRI during an affective Stroop task before and after intervention. Although both groups improved significantly on a response-inhibition task, only the MT group showed reduced affective Stroop conflict. Moreover, the MT group displayed greater dorsolateral prefrontal cortex (DLPFC) responses during executive processing, consistent with increased recruitment of top-down mechanisms to resolve conflict. In contrast, we did not observe overall group by time interactions on negative affect-related RTs or BOLD responses. However, only participants with the greatest amount of MT practice showed improvements in response-inhibition and increased recruitment of dorsal anterior cingulate cortex (dACC), medial prefrontal cortex (mPFC), and right anterior insula during negative valence processing. Collectively our findings highlight the importance of active control in MT research, and indicate unique neural mechanisms for progressive stages of mindfulness training. PMID:23115195

  11. 40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 12 2010-07-01 2010-07-01 true How do I know if my reinforced plastic... for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new affected source...

  12. 40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 12 2011-07-01 2009-07-01 true How do I know if my reinforced plastic... for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new affected source...

  13. Optimal level activity of matrix metalloproteinases is critical for adult visual plasticity in the healthy and stroke-affected brain.

    PubMed

    Pielecka-Fortuna, Justyna; Kalogeraki, Evgenia; Fortuna, Michal G; Löwel, Siegrid

    2016-01-01

    The ability of the adult brain to undergo plastic changes is of particular interest in medicine, especially regarding recovery from injuries or improving learning and cognition. Matrix metalloproteinases (MMPs) have been associated with juvenile experience-dependent primary visual cortex (V1) plasticity, yet little is known about their role in this process in the adult V1. Activation of MMPs is a crucial step facilitating structural changes in a healthy brain; however, upon brain injury, upregulated MMPs promote the spread of a lesion and impair recovery. To clarify these seemingly opposing outcomes of MMP-activation, we examined the effects of MMP-inhibition on experience-induced plasticity in healthy and stoke-affected adult mice. In healthy animals, 7-day application of MMP-inhibitor prevented visual plasticity. Additionally, treatment with MMP-inhibitor once but not twice following stroke rescued plasticity, normally lost under these conditions. Our data imply that an optimal level of MMP-activity is crucial for adult visual plasticity to occur. PMID:26609811

  14. Optimal level activity of matrix metalloproteinases is critical for adult visual plasticity in the healthy and stroke-affected brain

    PubMed Central

    Pielecka-Fortuna, Justyna; Kalogeraki, Evgenia; Fortuna, Michal G; Löwel, Siegrid

    2015-01-01

    The ability of the adult brain to undergo plastic changes is of particular interest in medicine, especially regarding recovery from injuries or improving learning and cognition. Matrix metalloproteinases (MMPs) have been associated with juvenile experience-dependent primary visual cortex (V1) plasticity, yet little is known about their role in this process in the adult V1. Activation of MMPs is a crucial step facilitating structural changes in a healthy brain; however, upon brain injury, upregulated MMPs promote the spread of a lesion and impair recovery. To clarify these seemingly opposing outcomes of MMP-activation, we examined the effects of MMP-inhibition on experience-induced plasticity in healthy and stoke-affected adult mice. In healthy animals, 7-day application of MMP-inhibitor prevented visual plasticity. Additionally, treatment with MMP-inhibitor once but not twice following stroke rescued plasticity, normally lost under these conditions. Our data imply that an optimal level of MMP-activity is crucial for adult visual plasticity to occur. DOI: http://dx.doi.org/10.7554/eLife.11290.001 PMID:26609811

  15. Spines slow down dendritic chloride diffusion and affect short-term ionic plasticity of GABAergic inhibition

    PubMed Central

    Mohapatra, Namrata; Tønnesen, Jan; Vlachos, Andreas; Kuner, Thomas; Deller, Thomas; Nägerl, U. Valentin; Santamaria, Fidel; Jedlicka, Peter

    2016-01-01

    Cl− plays a crucial role in neuronal function and synaptic inhibition. However, the impact of neuronal morphology on the diffusion and redistribution of intracellular Cl− is not well understood. The role of spines in Cl− diffusion along dendritic trees has not been addressed so far. Because measuring fast and spatially restricted Cl− changes within dendrites is not yet technically possible, we used computational approaches to predict the effects of spines on Cl− dynamics in morphologically complex dendrites. In all morphologies tested, including dendrites imaged by super-resolution STED microscopy in live brain tissue, spines slowed down longitudinal Cl− diffusion along dendrites. This effect was robust and could be observed in both deterministic as well as stochastic simulations. Cl− extrusion altered Cl− diffusion to a much lesser extent than the presence of spines. The spine-dependent slowing of Cl− diffusion affected the amount and spatial spread of changes in the GABA reversal potential thereby altering homosynaptic as well as heterosynaptic short-term ionic plasticity at GABAergic synapses in dendrites. Altogether, our results suggest a fundamental role of dendritic spines in shaping Cl− diffusion, which could be of relevance in the context of pathological conditions where spine densities and neural excitability are perturbed. PMID:26987404

  16. Social competition affects electric signal plasticity and steroid levels in the gymnotiform fish Brachyhypopomus gauderio

    PubMed Central

    Salazar, Vielka L.; Stoddard, Philip K.

    2009-01-01

    Sexually-selected communication signals can be used by competing males to settle contests without incurring the costs of fighting. Steroid regulation of these signals can render them as reliable indicators of a male's physiological state. We investigated how plasticity in electrocommunication signals is driven by social competition for mates, mediated by steroid hormones, and subject to the effects of past social experience. We measured the electric waveform's amplitude and duration and steroid hormone levels of male gymnotiform electric fish (Brachyhypopomus gauderio) following week-long periods of social isolation, and low or high social competition. To quantify the effect of social history on the modulation of the electric signal, six groups of six males experienced all the above three social conditions but in different order. We found that males differentially modulate their electric signals depending on the order they experienced these conditions. Thus, past social interactions affect both present and future social electric signals. Cortisol levels and the amplitude of the electric signal appeared to track the intensity of competition, while androgen levels and the duration of the electric signal only responded to the presence (low and high competition) or absence (isolation) of a social environment (low and high androgens respectively). In addition, cortisol levels were related to the body size of the males at high social competition. Taken together, these findings suggest that the capacity of males to modulate their signals in response to social competition is regulated by steroids. PMID:19647742

  17. Spines slow down dendritic chloride diffusion and affect short-term ionic plasticity of GABAergic inhibition

    NASA Astrophysics Data System (ADS)

    Mohapatra, Namrata; Tønnesen, Jan; Vlachos, Andreas; Kuner, Thomas; Deller, Thomas; Nägerl, U. Valentin; Santamaria, Fidel; Jedlicka, Peter

    2016-03-01

    Cl‑ plays a crucial role in neuronal function and synaptic inhibition. However, the impact of neuronal morphology on the diffusion and redistribution of intracellular Cl‑ is not well understood. The role of spines in Cl‑ diffusion along dendritic trees has not been addressed so far. Because measuring fast and spatially restricted Cl‑ changes within dendrites is not yet technically possible, we used computational approaches to predict the effects of spines on Cl‑ dynamics in morphologically complex dendrites. In all morphologies tested, including dendrites imaged by super-resolution STED microscopy in live brain tissue, spines slowed down longitudinal Cl‑ diffusion along dendrites. This effect was robust and could be observed in both deterministic as well as stochastic simulations. Cl‑ extrusion altered Cl‑ diffusion to a much lesser extent than the presence of spines. The spine-dependent slowing of Cl‑ diffusion affected the amount and spatial spread of changes in the GABA reversal potential thereby altering homosynaptic as well as heterosynaptic short-term ionic plasticity at GABAergic synapses in dendrites. Altogether, our results suggest a fundamental role of dendritic spines in shaping Cl‑ diffusion, which could be of relevance in the context of pathological conditions where spine densities and neural excitability are perturbed.

  18. Stress and hippocampal plasticity: implications for the pathophysiology of affective disorders.

    PubMed

    McEwen, Bruce S.; Magarinos, Ana Maria

    2001-01-01

    The hippocampal formation, a structure involved in declarative, spatial and contextual memory, is a particularly sensitive and vulnerable brain region to stress and stress hormones. The hippocampus shows a considerable degree of structural plasticity in the adult brain. Stress suppresses neurogenesis of dentate gyrus granule neurons, and repeated stress causes atrophy of dendrites in the CA3 region. In addition, ovarian steroids regulate synapse formation during the estrous cycle of female rats. All three forms of structural remodeling of the hippocampus are mediated by hormones working in concert with excitatory amino acids (EAA) and N-methyl-D-aspartate (NMDA) receptors. EAA and NMDA receptors are also involved in neuronal death that is caused in pyramidal neurons by seizures and by ischemia and prolonged psychosocial stress. In the human hippocampus, magnetic resonance imaging studies have shown that there is a selective atrophy in recurrent depressive illness, accompanied by deficits in memory performance. Hippocampal atrophy may be a feature of affective disorders that is not treated by all medications. From a therapeutic standpoint, it is essential to distinguish between permanent damage and reversible atrophy in order to develop treatment strategies to either prevent or reverse deficits. In addition, remodeling of brain cells may occur in other brain regions. Possible treatments are discussed. Copyright 2001 John Wiley & Sons, Ltd. PMID:12404531

  19. Low-Volatility Model Demonstrates Humidity Affects Environmental Toxin Deposition on Plastics at a Molecular Level.

    PubMed

    Hankett, Jeanne M; Collin, William R; Yang, Pei; Chen, Zhan; Duhaime, Melissa

    2016-02-01

    Despite the ever-increasing prevalence of plastic debris and endocrine disrupting toxins in aquatic ecosystems, few studies describe their interactions in freshwater environments. We present a model system to investigate the deposition/desorption behaviors of low-volatility lake ecosystem toxins on microplastics in situ and in real time. Molecular interactions of gas-phase nonylphenols (NPs) with the surfaces of two common plastics, poly(styrene) and poly(ethylene terephthalate), were studied using quartz crystal microbalance and sum frequency generation vibrational spectroscopy. NP point sources were generated under two model environments: plastic on land and plastic on a freshwater surface. We found the headspace above calm water provides an excellent environment for NP deposition and demonstrate significant NP deposition on plastic within minutes at relevant concentrations. Further, NP deposits and orders differently on both plastics under humid versus dry environments. We attributed the unique deposition behaviors to surface energy changes from increased water content during the humid deposition. Lastly, nanograms of NP remained on microplastic surfaces hours after initial NP introduction and agitating conditions, illustrating feasibility for plastic-bound NPs to interact with biota and surrounding matter. Our model studies reveal important interactions between low-volatility environmental toxins and microplastics and hold potential to correlate the environmental fate of endocrine disrupting toxins in the Great Lakes with molecular behaviors. PMID:26752114

  20. Progressive deformation of ultramafic rocks accompanied with deflection of layered structure and mylonitization culminating into a pseudotachylyte-bearing seismogenic fault - a field evidence of plastic instability

    NASA Astrophysics Data System (ADS)

    Ueda, T.; Obata, M.

    2011-12-01

    Plastic instability leading to rupture nucleation and propagetion (e.g. Hobbs et al.1986, Kelemen and Hirth, 2007) is an attractive hypothesis for deep earthquakes but lacked clear field evidences. 1D across-fault shear localization observed in some places (e.g. Jin et al.1998) is not clear if the deformation is directly related with seismicity. We present a clear field evidence of plastic instability as guided by pyroxenite/peridotite layering deflection structure (hereafter called LD structure, see figure) accompanied with mylonitization in spinel(Sp)-peridotite facies (P>~1GPa) in Balmuccia peridotite, Ivrea-Verbano Zone, Italy. The studied area contains abundant PST-bearing faults and N-S trending primary pyroxenite layers. Many faults in the area cut pyroxenite layers, but LD structure is found only in one place presented here. Many PSTs in the area have been (re)crystallized in Sp-peridotite facies, and have typically ultramylonitic texture (Ueda et al., 2008) with some injection veins. The fault with LD structure is situated in a fault system, which has two dominant attitudes with regional N-S extension. The shear strain of LD structure measured on outcrop surface is ~2.0. Near the fault, elongated Opx porphyroclasts (ellipses in figure) oblique to local layering are visible in peridotite. The dominant deformation textures are dynamic recrystallization in peridotite and kinking or undulatory extinction in pyroxenite. The mineral assemblages of the mylonite neoblast in the peridotite and the pyroxenite are Ol+Opx+Cpx+Sp+hornblende(Hbl), Cpx+Opx+Sp, respectively. Hbl typically occur only in neoblast. In the vicinity (several hundreds of micron) of the fault, dolomite(Dol) also occur in equilibrium with the assemblage above. The recrystallized grain sizes are 20-50 microns in peridotite and 10-30 microns in pyroxenite. The rarity of LD structure is consistent with general conception that deformation processes which lead to dynamic rupture initiation ought to be

  1. Legal and institutional tools to mitigate plastic pollution affecting marine species: Argentina as a case study.

    PubMed

    González Carman, Victoria; Machain, Natalia; Campagna, Claudio

    2015-03-15

    Plastics are the most common form of debris found along the Argentine coastline. The Río de la Plata estuarine area is a relevant case study to describe a situation where ample policy exists against a backdrop of plastics disposed by populated coastal areas, industries, and vessels; with resultant high impacts of plastic pollution on marine turtles and mammals. Policy and institutions are in place but the impact remains due to ineffective waste management, limited public education and awareness, and weaknesses in enforcement of regulations. This context is frequently repeated all over the world. We list possible interventions to increase the effectiveness of policy that require integrating efforts among governments, the private sector, non-governmental organizations and the inhabitants of coastal cities to reduce the amount of plastics reaching the Río de la Plata and protect threatened marine species. What has been identified for Argentina applies to the region and globally. PMID:25627195

  2. Fertilization and Colors of Plastic Mulch Affect Biomass and Essential Oil of Sweet-Scented Geranium

    PubMed Central

    Silva, Anderson de Carvalho; dos Santos, Wallace Melo; Prata, Paloma Santana; Alves, Péricles Barreto

    2014-01-01

    Sweet-scented geranium (Pelargonium graveolens L'Hér), a plant belonging to the Geraniaceae family, has medicinal and aromatic properties and is widely used in the cosmetic, soap, perfume, aromatherapy, and food industries. The aim of this study was to evaluate the influence of fertilization and the use of different colors of plastic mulch on sweet-scented geranium biomass and essential oil. Three colors of plastic mulch (black, white, and silver-colored) and a control without plastic mulch were assessed along with three fertilizers (20,000 L·ha−1 of cattle manure; 1,000 kg·ha−1 of NPK 3-12-6; and 20,000 L·ha−1 of cattle manure + 1,000 kg·ha−1 of NPK 3-12-6 fertilizer) and a control without fertilizer. The absence of a soil cover negatively influenced the agronomical variables, while coverage with plastic mulch was associated with increased biomass. The use of fertilizer had no effect on the evaluated agronomic variables. When cattle manure and NPK 3-12-6 were used together, combined with white or black plastic mulch, the highest yields of essential oil were obtained. For the silver-colored plastic mulch, higher amounts of essential oil (6,9-guaiadien) were obtained with mineral fertilizer. PMID:24757440

  3. Fertilization and colors of plastic mulch affect biomass and essential oil of sweet-scented geranium.

    PubMed

    Silva, Anderson de Carvalho; Blank, Arie Fitzgerald; dos Santos, Wallace Melo; Prata, Paloma Santana; Alves, Péricles Barreto; Arrigoni-Blank, Maria de Fátima

    2014-01-01

    Sweet-scented geranium (Pelargonium graveolens L'Hér), a plant belonging to the Geraniaceae family, has medicinal and aromatic properties and is widely used in the cosmetic, soap, perfume, aromatherapy, and food industries. The aim of this study was to evaluate the influence of fertilization and the use of different colors of plastic mulch on sweet-scented geranium biomass and essential oil. Three colors of plastic mulch (black, white, and silver-colored) and a control without plastic mulch were assessed along with three fertilizers (20,000 L · ha(-1) of cattle manure; 1,000 kg · ha(-1) of NPK 3-12-6; and 20,000 L · ha(-1) of cattle manure + 1,000 kg · ha(-1) of NPK 3-12-6 fertilizer) and a control without fertilizer. The absence of a soil cover negatively influenced the agronomical variables, while coverage with plastic mulch was associated with increased biomass. The use of fertilizer had no effect on the evaluated agronomic variables. When cattle manure and NPK 3-12-6 were used together, combined with white or black plastic mulch, the highest yields of essential oil were obtained. For the silver-colored plastic mulch, higher amounts of essential oil (6,9-guaiadien) were obtained with mineral fertilizer. PMID:24757440

  4. Are the interpersonal and identity disturbances in the borderline personality disorder criteria linked to the traits of affective instability and impulsivity?

    PubMed

    Koenigsberg, H W; Harvey, P D; Mitropoulou, V; New, A S; Goodman, M; Silverman, J; Serby, M; Schopick, F; Siever, L J

    2001-08-01

    This study examines the degree to which two putative biologically influenced personality traits, affective instability and impulsive aggression, are associated with some of the interpersonal and intrapsychic disturbances of borderline personality disorder (BPD) and with choice of defense mechanism. In a sample of 152 personality disorder patients, affective instability and impulsive aggression were measured. Defense mechanisms were assessed in 140 of these patients using the Defensive Style Questionnaire (DSQ). The correlations between the traits of affective instability and impulsive aggression and the eight DSM-III-R criteria for borderline personality disorder and 20 DSQ defenses were examined. Affective instability was significantly correlated with the DSM-III-R criteria of identity disturbance, chronic emptiness or boredom, inappropriate anger, suicidality, and the affective instability criteria. It also was associated with the defenses of splitting, projection, acting out, passive aggression, undoing, and autistic fantasy. Impulsive aggression was related to unstable interpersonal relationships, inappropriate anger and impulsiveness and with the defense of acting out. It was negatively correlated with the defenses of suppression and reaction formation. A number of the interpersonal and experiential disturbances and defense mechanisms that are features of BPD are associated with the traits of affective instability and impulsive aggression among patients with personality disorders. PMID:11556702

  5. COULD COSMIC RAYS AFFECT INSTABILITIES IN THE TRANSITION LAYER OF NONRELATIVISTIC COLLISIONLESS SHOCKS?

    SciTech Connect

    Stroman, Thomas; Pohl, Martin; Niemiec, Jacek; Bret, Antoine

    2012-02-10

    There is an observational correlation between astrophysical shocks and nonthermal particle distributions extending to high energies. As a first step toward investigating the possible feedback of these particles on the shock at the microscopic level, we perform particle-in-cell (PIC) simulations of a simplified environment consisting of uniform, interpenetrating plasmas, both with and without an additional population of cosmic rays. We vary the relative density of the counterstreaming plasmas, the strength of a homogeneous parallel magnetic field, and the energy density in cosmic rays. We compare the early development of the unstable spectrum for selected configurations without cosmic rays to the growth rates predicted from linear theory, for assurance that the system is well represented by the PIC technique. Within the parameter space explored, we do not detect an unambiguous signature of any cosmic-ray-induced effects on the microscopic instabilities that govern the formation of a shock. We demonstrate that an overly coarse distribution of energetic particles can artificially alter the statistical noise that produces the perturbative seeds of instabilities, and that such effects can be mitigated by increasing the density of computational particles.

  6. Investigation of instabilities affecting detonations: Improving the resolution using block-structured adaptive mesh refinement

    NASA Astrophysics Data System (ADS)

    Ravindran, Prashaanth

    The unstable nature of detonation waves is a result of the critical relationship between the hydrodynamic shock and the chemical reactions sustaining the shock. A perturbative analysis of the critical point is quite challenging due to the multiple spatio-temporal scales involved along with the non-linear nature of the shock-reaction mechanism. The author's research attempts to provide detailed resolution of the instabilities at the shock front. Another key aspect of the present research is to develop an understanding of the causality between the non-linear dynamics of the front and the eventual breakdown of the sub-structures. An accurate numerical simulation of detonation waves requires a very efficient solution of the Euler equations in conservation form with detailed, non-equilibrium chemistry. The difference in the flow and reaction length scales results in very stiff source terms, requiring the problem to be solved with adaptive mesh refinement. For this purpose, Berger-Colella's block-structured adaptive mesh refinement (AMR) strategy has been developed and applied to time-explicit finite volume methods. The block-structured technique uses a hierarchy of parent-child sub-grids, integrated recursively over time. One novel approach to partition the problem within a large supercomputer was the use of modified Peano-Hilbert space filling curves. The AMR framework was merged with CLAWPACK, a package providing finite volume numerical methods tailored for wave-propagation problems. The stiffness problem is bypassed by using a 1st order Godunov or a 2nd order Strang splitting technique, where the flow variables and source terms are integrated independently. A linearly explicit fourth-order Runge-Kutta integrator is used for the flow, and an ODE solver was used to overcome the numerical stiffness. Second-order spatial resolution is obtained by using a second-order Roe-HLL scheme with the inclusion of numerical viscosity to stabilize the solution near the discontinuity

  7. EMPIRICAL MODELING OF PHYSICAL PROPERTIES OF CASEIN FILMS AS AFFECTED BY PLASTICIZER CONTENT

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Casein films have the potential to be used to improve the quality and safety of food or to be used as biodegradable packaging. Plasticizers are incorporated into protein films to lower the glass transition temperature (Tg) and to improve tensile properties relative to pure films. The extent that p...

  8. TRUNK SPROUTING AND GROWTH OF CITRUS AS AFFECTED BY NAA, ALUMINUM FOIL, AND PLASTIC TRUNK WRAPS

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In spring 1999, a commercial NAA (1-naphthaleneacetic acid) preparation for trunk sprout inhibition was compared to a corrugated plastic trunk wrap, aluminum foil wrap, bimonthly hand-removal of sprouts, use of NAA preparation plus bimonthly hand-removal when sprouts appeared, and a non-treated cont...

  9. Within- and trans-generational plasticity affects the opportunity for selection in barbed goatgrass (Aegilops Triuncialis)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Although genetic change can enhance the success of many biological invaders, phenotypic plasticity may also facilitate establishment and spread of introduced species in new environments. To determine if processes influencing the opportunity for selection differ between resource- rich and resource- p...

  10. Hip instability.

    PubMed

    Smith, Matthew V; Sekiya, Jon K

    2010-06-01

    Hip instability is becoming a more commonly recognized source of pain and disability in patients. Traumatic causes of hip instability are often clear. Appropriate treatment includes immediate reduction, early surgery for acetabular rim fractures greater than 25% or incarcerated fragments in the joint, and close follow-up to monitor for avascular necrosis. Late surgical intervention may be necessary for residual symptomatic hip instability. Atraumatic causes of hip instability include repetitive external rotation with axial loading, generalized ligamentous laxity, and collagen disorders like Ehlers-Danlos. Symptoms caused by atraumatic hip instability often have an insidious onset. Patients may have a wide array of hip symptoms while demonstrating only subtle findings suggestive of capsular laxity. Traction views of the affected hip can be helpful in diagnosing hip instability. Open and arthroscopic techniques can be used to treat capsular laxity. We describe an arthroscopic anterior hip capsular plication using a suture technique. PMID:20473129

  11. Intra-day signal instabilities affect decoding performance in an intracortical neural interface system

    NASA Astrophysics Data System (ADS)

    Perge, János A.; Homer, Mark L.; Malik, Wasim Q.; Cash, Sydney; Eskandar, Emad; Friehs, Gerhard; Donoghue, John P.; Hochberg, Leigh R.

    2013-06-01

    Objective. Motor neural interface systems (NIS) aim to convert neural signals into motor prosthetic or assistive device control, allowing people with paralysis to regain movement or control over their immediate environment. Effector or prosthetic control can degrade if the relationship between recorded neural signals and intended motor behavior changes. Therefore, characterizing both biological and technological sources of signal variability is important for a reliable NIS. Approach. To address the frequency and causes of neural signal variability in a spike-based NIS, we analyzed within-day fluctuations in spiking activity and action potential amplitude recorded with silicon microelectrode arrays implanted in the motor cortex of three people with tetraplegia (BrainGate pilot clinical trial, IDE). Main results. 84% of the recorded units showed a statistically significant change in apparent firing rate (3.8 ± 8.71 Hz or 49% of the mean rate) across several-minute epochs of tasks performed on a single session, and 74% of the units showed a significant change in spike amplitude (3.7 ± 6.5 µV or 5.5% of mean spike amplitude). 40% of the recording sessions showed a significant correlation in the occurrence of amplitude changes across electrodes, suggesting array micro-movement. Despite the relatively frequent amplitude changes, only 15% of the observed within-day rate changes originated from recording artifacts such as spike amplitude change or electrical noise, while 85% of the rate changes most likely emerged from physiological mechanisms. Computer simulations confirmed that systematic rate changes of individual neurons could produce a directional ‘bias’ in the decoded neural cursor movements. Instability in apparent neuronal spike rates indeed yielded a directional bias in 56% of all performance assessments in participant cursor control (n = 2 participants, 108 and 20 assessments over two years), resulting in suboptimal performance in these sessions

  12. Chromosome nondisjunction and instabilities in tapetal cells are affected by B chromosomes in maize.

    PubMed Central

    Chiavarino, A M; Rosato, M; Manzanero, S; Jiménez, G; González-Sánchez, M; Puertas, M J

    2000-01-01

    Abnormal mitosis occurs in maize tapetum, producing binucleate cells that later disintegrate, following a pattern of programmed cell death. FISH allowed us to observe chromosome nondisjunction and micronucleus formation in binucleate cells, using DNA probes specific to B chromosomes (B's), knobbed chromosomes, and the chromosome 6 (NOR) of maize. All chromosome types seem to be involved in micronucleus formation, but the B's form more micronuclei than do knobbed chromosomes and knobbed chromosomes form more than do chromosomes without knobs. Micronuclei were more frequent in 1B plants and in a genotype selected for low B transmission rate. Nondisjunction was observed in all types of FISH-labeled chromosomes. In addition, unlabeled bridges and delayed chromatids were observed in the last telophase before binucleate cell formation, suggesting that nondisjunction might occur in all chromosomes of the maize complement. B nondisjunction is known to occur in the second pollen mitosis and in the endosperm, but it was not previously reported in other tissues. This is also a new report of nondisjunction of chromosomes of the normal set (A's) in tapetal cells. Our results support the conclusion that nondisjunction and micronucleus formation are regular events in the process of the tapetal cell death program, but B's strongly increase A chromosome instability. PMID:10835407

  13. Influence of system size on spatiotemporal dynamics of a model for plastic instability: Projecting low-dimensional and extensive chaos

    NASA Astrophysics Data System (ADS)

    Sarmah, Ritupan; Ananthakrishna, G.

    2013-05-01

    This work is a continuation of our efforts to quantify the irregular scalar stress signals from the Ananthakrishna model for the Portevin-Le Chatelier instability observed under constant strain rate deformation conditions. Stress related to the spatial average of the dislocation activity is a dynamical variable that also determines the time evolution of dislocation densities. We carry out detailed investigations on the nature of spatiotemporal patterns of the model realized in the form of different types of dislocation bands seen in the entire instability domain and establish their connection to the nature of stress serrations. We then characterize the spatiotemporal dynamics of the model equations by computing the Lyapunov dimension as a function of the drive parameter. The latter scales with the system size only for low strain rates, where isolated dislocation bands are seen, and at high strain rates, where fully propagating bands are seen. At intermediate applied strain rates corresponding to the partially propagating bands, the Lyapunov dimension exhibits two distinct slopes, one for small system sizes and another for large. This feature is rationalized by demonstrating that the spatiotemporal patterns for small system sizes are altered from the partially propagating band types to isolated burst type. This in turn allows us to reconfirm that low-dimensional chaos is projected from the stress signals as long as there is a one-to-one correspondence between the bursts of dislocation bands and the stress drops. We then show that the stress signals in the regime of partially to fully propagative bands have features of extensive chaos by calculating the correlation dimension density. We also show that the correlation dimension density also depends on the system size. A number of issues related to the system size dependence of the Lyapunov dimension density and the correlation dimension density are discussed.

  14. Influence of system size on spatiotemporal dynamics of a model for plastic instability: projecting low-dimensional and extensive chaos.

    PubMed

    Sarmah, Ritupan; Ananthakrishna, G

    2013-05-01

    This work is a continuation of our efforts to quantify the irregular scalar stress signals from the Ananthakrishna model for the Portevin-Le Chatelier instability observed under constant strain rate deformation conditions. Stress related to the spatial average of the dislocation activity is a dynamical variable that also determines the time evolution of dislocation densities. We carry out detailed investigations on the nature of spatiotemporal patterns of the model realized in the form of different types of dislocation bands seen in the entire instability domain and establish their connection to the nature of stress serrations. We then characterize the spatiotemporal dynamics of the model equations by computing the Lyapunov dimension as a function of the drive parameter. The latter scales with the system size only for low strain rates, where isolated dislocation bands are seen, and at high strain rates, where fully propagating bands are seen. At intermediate applied strain rates corresponding to the partially propagating bands, the Lyapunov dimension exhibits two distinct slopes, one for small system sizes and another for large. This feature is rationalized by demonstrating that the spatiotemporal patterns for small system sizes are altered from the partially propagating band types to isolated burst type. This in turn allows us to reconfirm that low-dimensional chaos is projected from the stress signals as long as there is a one-to-one correspondence between the bursts of dislocation bands and the stress drops. We then show that the stress signals in the regime of partially to fully propagative bands have features of extensive chaos by calculating the correlation dimension density. We also show that the correlation dimension density also depends on the system size. A number of issues related to the system size dependence of the Lyapunov dimension density and the correlation dimension density are discussed. PMID:23767598

  15. Borderline personality features and instability of daily negative affect and self-esteem.

    PubMed

    Tolpin, Laura Hochschild; Gunthert, Kathleen Cimbolic; Cohen, Lawrence H; O'Neill, Suzanne C

    2004-02-01

    We used a daily process design and multilevel modeling to examine the role of borderline personality features in the day-to-day stability of college students' negative affect and self-esteem and their reactivity to interpersonal stressors. At the end of each day for two weeks, students completed a checklist of daily stressors and measures of state affect and self-esteem. We predicted that high scores on a measure of borderline features would be related to more daily interpersonal stressors, greater negative affective and self-esteem reactivity to these stressors, and less day-to-day carryover of negative mood and self-esteem. The first and third hypotheses were supported, but not the second. The findings demonstrate the utility of a daily process methodology and multilevel modeling to study the day-to-day functioning of individuals with borderline features. PMID:14686886

  16. The Clinical Significance of Single Features of Borderline Personality Disorder: Anger, Affective Instability, Impulsivity, and Chronic Emptiness in Psychiatric Outpatients.

    PubMed

    Ellison, William D; Rosenstein, Lia; Chelminski, Iwona; Dalrymple, Kristy; Zimmerman, Mark

    2016-04-01

    Although dimensional models of borderline personality disorder (BPD) are consistent with findings showing that minimal levels of pathology are associated with substantial increases in psychosocial impairment, it is still unclear whether different individual BPD criteria are each clinically significant on their own. The current study uses semistructured interview data from 1,870 adults presenting for outpatient psychiatric treatment to investigate whether the BPD criteria of impulsivity, affective instability, emptiness, and anger are each related to psychosocial morbidity when met in the absence of the other eight criteria. Analyses showed that each of these criteria was associated with dysfunction in comparison with a control group meeting zero BPD criteria, but only the emptiness criterion was a marker of impairment on all indices of psychosocial morbidity: suicidality, history of suicide attempts and psychiatric hospitalizations, social and work dysfunction, Axis I comorbidity, and global functioning. Implications for the study of borderline pathology are discussed. PMID:25893552

  17. Phenotypic plasticity in growth and fecundity induced by strong population fluctuations affects reproductive traits of female fish.

    PubMed

    Karjalainen, Juha; Urpanen, Olli; Keskinen, Tapio; Huuskonen, Hannu; Sarvala, Jouko; Valkeajärvi, Pentti; Marjomäki, Timo J

    2016-02-01

    Fish are known for their high phenotypic plasticity in life-history traits in relation to environmental variability, and this is particularly pronounced among salmonids in the Northern Hemisphere. Resource limitation leads to trade-offs in phenotypic plasticity between life-history traits related to the reproduction, growth, and survival of individual fish, which have consequences for the age and size distributions of populations, as well as their dynamics and productivity. We studied the effect of plasticity in growth and fecundity of vendace females on their reproductive traits using a series of long-term incubation experiments. The wild parental fish originated from four separate populations with markedly different densities, and hence naturally induced differences in their growth and fecundity. The energy allocation to somatic tissues and eggs prior to spawning served as a proxy for total resource availability to individual females, and its effects on offspring survival and growth were analyzed. Vendace females allocated a rather constant proportion of available energy to eggs (per body mass) despite different growth patterns depending on the total resources in the different lakes; investment into eggs thus dictated the share remaining for growth. The energy allocation to eggs per mass was higher in young than in old spawners and the egg size and the relative fecundity differed between them: Young females produced more and smaller eggs and larvae than old spawners. In contrast to earlier observations of salmonids, a shortage of maternal food resources did not increase offspring size and survival. Vendace females in sparse populations with ample resources and high growth produced larger eggs and larvae. Vendace accommodate strong population fluctuations by their high plasticity in growth and fecundity, which affect their offspring size and consequently their recruitment and productivity, and account for their persistence and resilience in the face of high

  18. Identification of critical factors for the instability of permafrost-affected rockwalls in the Turtmann valley (Swiss Alps)

    NASA Astrophysics Data System (ADS)

    Messenzehl, Karoline; Draebing, Daniel; Dikau, Richard

    2014-05-01

    Rock slope instability, small-scale rockfalls and associated talus slopes are widespread phenomena in mountain environments. The heterogeneous spatial pattern, sediment properties and volume of talus deposits in alpine valleys reflect a complicated set of various variables governing the spatial and temporal occurrence of slope failure. However, the dynamic and non-linear interplay between environmental settings, the mechanical properties of the rock mass, its discontinuities and different weathering processes promoting rock degradation makes the identification of the dominant destabilizing factors a difficult task. In our project we studied the instability of permafrost-affected rockwalls (Nyenhuis et al., 2005) in the high alpine Turtmann Valley in the Swiss Alps (110 km2). Here, we present a combination of (i) meso-scale spatial analyses and (ii) local-scale geotechnical investigations of critical factors on rockwall instability and (iii) incorporate the results into a theoretical concept with respect to abiotic and biotic weathering processes. (i) To explain the spatial variability of talus deposits stored in 14 WE-oriented hanging valleys, a detailed geomorphological map of 220 talus slopes (Otto et al. 2009) was spatially combined with different key variables of the rockfall source area including topography, climate, lithology and rockwall morphometry. The talus slopes are strongly oriented towards north indicating reduced solar radiation. This aspect-driven trend appears to support the high significance of frost weathering processes as dominant mechanism for rock slope instability, in particular during thawing phases of rockwall permafrost. (ii) To assess the role of mechanical properties of rockwalls at local scales, field surveys of rock discontinuities were performed at selected rockwalls with and without talus slopes based on ISRM standards. Geotechnical investigations reveal discontinuity orientations and spacings that might effectively promote rock

  19. Microstructure and Mechanical Instability of Water-Quenched U-6wt% Nb Alloy Affected by Long-Term Aging

    SciTech Connect

    Hsiung, L; Zhou, J

    2005-12-06

    A combinative approach of microhardness testing, tensile testing, and TEM microstructural analysis was employed to study the microstructure and mechanical instability of a water-quenched U-6wt.% Nb (WQ-U6Nb) alloy subjected to different aging schedules including artificial aging at 200 C, 15-year natural aging at ambient temperatures, and 15-year natural aging followed by accelerative aging at 200 C. The changes in mechanical property during and after the aging processes were examined using microhardness and tensile-testing methods. During the early stages of artificial aging at 200 C, the microhardness of WQ-U6Nb alloy increased, i.e., age hardening, as a result of the development of nanoscale modulation caused by spinodal decomposition. Coarsening of the modulated structure occurred after a prolonged aging at 200 C for 16 hours, and it led to a decrease of microhardness, i.e., age softening. Phase instability was also found to occur in WQ-U6Nb alloy that was subjected to a 15-year natural aging at ambient temperatures. The formation of partially ordered domains resulting from a spinodal modulation with an atomic-scale wavelength rendered the appearance of swirl-shape antiphase domain boundaries (APBs) observed in TEM images. Although it did not cause a significant change in microhardness, 15-year natural aging has dramatically affected the aging mechanisms of the alloy isothermally aged at 200 C. Microhardness values of the NA alloy continuously increased and no age softening was found after isothermal aging at 200 C for 96 hours as a result of the phase decomposition of partially ordered domains into Nb-depleted {alpha} phase and Nb-enriched U{sub 3}Nb ordered phase in the alloy. It is concluded that the long-term natural aging changes the transformation pathway of WQ-U6Nb, and it leads to order-disorder transformation, precipitation hardening, and ductility embrittlement of WQ-U6Nb alloy.

  20. How does visual language affect crossmodal plasticity and cochlear implant success?

    PubMed Central

    Lyness, C.R.; Woll, B.; Campbell, R.; Cardin, V.

    2013-01-01

    Cochlear implants (CI) are the most successful intervention for ameliorating hearing loss in severely or profoundly deaf children. Despite this, educational performance in children with CI continues to lag behind their hearing peers. From animal models and human neuroimaging studies it has been proposed the integrative functions of auditory cortex are compromised by crossmodal plasticity. This has been argued to result partly from the use of a visual language. Here we argue that ‘cochlear implant sensitive periods’ comprise both auditory and language sensitive periods, and thus cannot be fully described with animal models. Despite prevailing assumptions, there is no evidence to link the use of a visual language to poorer CI outcome. Crossmodal reorganisation of auditory cortex occurs regardless of compensatory strategies, such as sign language, used by the deaf person. In contrast, language deprivation during early sensitive periods has been repeatedly linked to poor language outcomes. Language sensitive periods have largely been ignored when considering variation in CI outcome, leading to ill-founded recommendations concerning visual language in CI habilitation. PMID:23999083

  1. Maternal care differentially affects neuronal excitability and synaptic plasticity in the dorsal and ventral hippocampus.

    PubMed

    Nguyen, Huy-Binh; Bagot, Rosemary C; Diorio, Josie; Wong, Tak Pan; Meaney, Michael J

    2015-06-01

    Variations in early life maternal care modulate hippocampal development to program distinct emotional-cognitive phenotypes that persist into adulthood. Adult rat offspring that received low compared with high levels of maternal licking and grooming (low LG offspring) in early postnatal life show reduced long term potentiation (LTP) and impaired hippocampal-dependent memory, suggesting a 'detrimental' maternal effect on neural development. However, these studies focused uniquely on the dorsal hippocampus. Emerging evidence suggests a distinct role of the ventral hippocampus in mediating aggression, anxiety, and fear-memory formation, which are enhanced in low LG offspring. We report that variations in maternal care in the rat associate with opposing effects on hippocampal function in the dorsal and ventral hippocampus. Reduced pup licking associated with suppressed LTP formation in the dorsal hippocampus, but enhanced ventral hippocampal LTP. Ventral hippocampal neurons in low LG offspring fired action potentials at lower threshold voltages that were of larger amplitude and faster rise rate in comparison with those in high LG offspring. Furthermore, recordings of excitatory postsynaptic potential-to-spike coupling (E-S coupling) revealed an increase in excitability of ventral hippocampal CA1 neurons in low LG offspring. These effects do not associate with changes in miniature excitatory postsynaptic currents or paired-pulse facilitation, suggesting a specific effect of maternal care on intrinsic excitability. These findings suggest region-specific influences of maternal care in shaping neural development and synaptic plasticity. PMID:25598429

  2. Maternal Care Differentially Affects Neuronal Excitability and Synaptic Plasticity in the Dorsal and Ventral Hippocampus

    PubMed Central

    Nguyen, Huy-Binh; Bagot, Rosemary C; Diorio, Josie; Wong, Tak Pan; Meaney, Michael J

    2015-01-01

    Variations in early life maternal care modulate hippocampal development to program distinct emotional–cognitive phenotypes that persist into adulthood. Adult rat offspring that received low compared with high levels of maternal licking and grooming (low LG offspring) in early postnatal life show reduced long term potentiation (LTP) and impaired hippocampal-dependent memory, suggesting a ‘detrimental' maternal effect on neural development. However, these studies focused uniquely on the dorsal hippocampus. Emerging evidence suggests a distinct role of the ventral hippocampus in mediating aggression, anxiety, and fear-memory formation, which are enhanced in low LG offspring. We report that variations in maternal care in the rat associate with opposing effects on hippocampal function in the dorsal and ventral hippocampus. Reduced pup licking associated with suppressed LTP formation in the dorsal hippocampus, but enhanced ventral hippocampal LTP. Ventral hippocampal neurons in low LG offspring fired action potentials at lower threshold voltages that were of larger amplitude and faster rise rate in comparison with those in high LG offspring. Furthermore, recordings of excitatory postsynaptic potential-to-spike coupling (E-S coupling) revealed an increase in excitability of ventral hippocampal CA1 neurons in low LG offspring. These effects do not associate with changes in miniature excitatory postsynaptic currents or paired-pulse facilitation, suggesting a specific effect of maternal care on intrinsic excitability. These findings suggest region-specific influences of maternal care in shaping neural development and synaptic plasticity. PMID:25598429

  3. Plasticity-Related Gene 1 Affects Mouse Barrel Cortex Function via Strengthening of Glutamatergic Thalamocortical Transmission.

    PubMed

    Unichenko, Petr; Kirischuk, Sergei; Yang, Jenq-Wei; Baumgart, Jan; Roskoden, Thomas; Schneider, Patrick; Sommer, Angela; Horta, Guilherme; Radyushkin, Konstantin; Nitsch, Robert; Vogt, Johannes; Luhmann, Heiko J

    2016-07-01

    Plasticity-related gene-1 (PRG-1) is a brain-specific protein that modulates glutamatergic synaptic transmission. Here we investigated the functional role of PRG-1 in adolescent and adult mouse barrel cortex both in vitro and in vivo. Compared with wild-type (WT) animals, PRG-1-deficient (KO) mice showed specific behavioral deficits in tests assessing sensorimotor integration and whisker-based sensory discrimination as shown in the beam balance/walking test and sandpaper tactile discrimination test, respectively. At P25-31, spontaneous network activity in the barrel cortex in vivo was higher in KO mice compared with WT littermates, but not at P16-19. At P16-19, sensory evoked cortical responses in vivo elicited by single whisker stimulation were comparable in KO and WT mice. In contrast, at P25-31 evoked responses were smaller in amplitude and longer in duration in WT animals, whereas KO mice revealed no such developmental changes. In thalamocortical slices from KO mice, spontaneous activity was increased already at P16-19, and glutamatergic thalamocortical inputs to Layer 4 spiny stellate neurons were potentiated. We conclude that genetic ablation of PRG-1 modulates already at P16-19 spontaneous and evoked excitability of the barrel cortex, including enhancement of thalamocortical glutamatergic inputs to Layer 4, which distorts sensory processing in adulthood. PMID:26980613

  4. Plasticity-Related Gene 1 Affects Mouse Barrel Cortex Function via Strengthening of Glutamatergic Thalamocortical Transmission

    PubMed Central

    Unichenko, Petr; Kirischuk, Sergei; Yang, Jenq-Wei; Baumgart, Jan; Roskoden, Thomas; Schneider, Patrick; Sommer, Angela; Horta, Guilherme; Radyushkin, Konstantin; Nitsch, Robert; Vogt, Johannes; Luhmann, Heiko J.

    2016-01-01

    Plasticity-related gene-1 (PRG-1) is a brain-specific protein that modulates glutamatergic synaptic transmission. Here we investigated the functional role of PRG-1 in adolescent and adult mouse barrel cortex both in vitro and in vivo. Compared with wild-type (WT) animals, PRG-1-deficient (KO) mice showed specific behavioral deficits in tests assessing sensorimotor integration and whisker-based sensory discrimination as shown in the beam balance/walking test and sandpaper tactile discrimination test, respectively. At P25-31, spontaneous network activity in the barrel cortex in vivo was higher in KO mice compared with WT littermates, but not at P16-19. At P16-19, sensory evoked cortical responses in vivo elicited by single whisker stimulation were comparable in KO and WT mice. In contrast, at P25-31 evoked responses were smaller in amplitude and longer in duration in WT animals, whereas KO mice revealed no such developmental changes. In thalamocortical slices from KO mice, spontaneous activity was increased already at P16-19, and glutamatergic thalamocortical inputs to Layer 4 spiny stellate neurons were potentiated. We conclude that genetic ablation of PRG-1 modulates already at P16-19 spontaneous and evoked excitability of the barrel cortex, including enhancement of thalamocortical glutamatergic inputs to Layer 4, which distorts sensory processing in adulthood. PMID:26980613

  5. How does visual language affect crossmodal plasticity and cochlear implant success?

    PubMed

    Lyness, C R; Woll, B; Campbell, R; Cardin, V

    2013-12-01

    Cochlear implants (CI) are the most successful intervention for ameliorating hearing loss in severely or profoundly deaf children. Despite this, educational performance in children with CI continues to lag behind their hearing peers. From animal models and human neuroimaging studies it has been proposed the integrative functions of auditory cortex are compromised by crossmodal plasticity. This has been argued to result partly from the use of a visual language. Here we argue that 'cochlear implant sensitive periods' comprise both auditory and language sensitive periods, and thus cannot be fully described with animal models. Despite prevailing assumptions, there is no evidence to link the use of a visual language to poorer CI outcome. Crossmodal reorganisation of auditory cortex occurs regardless of compensatory strategies, such as sign language, used by the deaf person. In contrast, language deprivation during early sensitive periods has been repeatedly linked to poor language outcomes. Language sensitive periods have largely been ignored when considering variation in CI outcome, leading to ill-founded recommendations concerning visual language in CI habilitation. PMID:23999083

  6. Pancreatic β-Cell Adaptive Plasticity in Obesity Increases Insulin Production but Adversely Affects Secretory Function.

    PubMed

    Alarcon, Cristina; Boland, Brandon B; Uchizono, Yuji; Moore, Patrick C; Peterson, Bryan; Rajan, Suryalekha; Rhodes, Olivia S; Noske, Andrew B; Haataja, Leena; Arvan, Peter; Marsh, Bradly J; Austin, Jotham; Rhodes, Christopher J

    2016-02-01

    Pancreatic β-cells normally produce adequate insulin to control glucose homeostasis, but in obesity-related diabetes, there is a presumed deficit in insulin production and secretory capacity. In this study, insulin production was assessed directly in obese diabetic mouse models, and proinsulin biosynthesis was found to be contrastingly increased, coupled with a significant expansion of the rough endoplasmic reticulum (without endoplasmic reticulum stress) and Golgi apparatus, increased vesicular trafficking, and a depletion of mature β-granules. As such, β-cells have a remarkable capacity to produce substantial quantities of insulin in obesity, which are then made available for immediate secretion to meet increased metabolic demand, but this comes at the price of insulin secretory dysfunction. Notwithstanding, it can be restored. Upon exposing isolated pancreatic islets of obese mice to normal glucose concentrations, β-cells revert back to their typical morphology with restoration of regulated insulin secretion. These data demonstrate an unrealized dynamic adaptive plasticity of pancreatic β-cells and underscore the rationale for transient β-cell rest as a treatment strategy for obesity-linked diabetes. PMID:26307586

  7. Mesenchymal stem cell adhesion but not plasticity is affected by high substrate stiffness

    NASA Astrophysics Data System (ADS)

    Kal Van Tam, Janice; Uto, Koichiro; Ebara, Mitsuhiro; Pagliari, Stefania; Forte, Giancarlo; Aoyagi, Takao

    2012-12-01

    The acknowledged ability of synthetic materials to induce cell-specific responses regardless of biological supplies provides tissue engineers with the opportunity to find the appropriate materials and conditions to prepare tissue-targeted scaffolds. Stem and mature cells have been shown to acquire distinct morphologies in vitro and to modify their phenotype when grown on synthetic materials with tunable mechanical properties. The stiffness of the substrate used for cell culture is likely to provide cells with mechanical cues mimicking given physiological or pathological conditions, thus affecting the biological properties of cells. The sensitivity of cells to substrate composition and mechanical properties resides in multiprotein complexes called focal adhesions, whose dynamic modification leads to cytoskeleton remodeling and changes in gene expression. In this study, the remodeling of focal adhesions in human mesenchymal stem cells in response to substrate stiffness was followed in the first phases of cell-matrix interaction, using poly-ɛ-caprolactone planar films with similar chemical composition and different elasticity. As compared to mature dermal fibroblasts, mesenchymal stem cells showed a specific response to substrate stiffness, in terms of adhesion, as a result of differential focal adhesion assembly, while their multipotency as a bulk was not significantly affected by matrix compliance. Given the sensitivity of stem cells to matrix mechanics, the mechanobiology of such cells requires further investigations before preparing tissue-specific scaffolds.

  8. Factors Affecting the Plasticity of Sodium Chloride, Lithium Fluoride, and Magnesium Oxide Single Crystals. 1

    NASA Technical Reports Server (NTRS)

    Stearns, Carl A.; Pack, Ann E.; Lad, Robert A.

    1959-01-01

    A study was made of the relative magnitude of the effects of various factors on the ductility of single crystals of sodium chloride (NaCl), lithium fluoride (LiF), and magnesium oxide (MgO). Specimen treatments included water-polishing, varying cleavage rate, annealing, quenching, X-irradiation, surface coating, aging, and combinations of some of these treatments. The mechanical behavior of the crystals was studied in flexure and in compression, the latter study being performed at both constant strain rate and constant load. Etch-pit studies were carried out to provide some pertinent information on the results of pretreatment on the dislocation concentration and distribution in the vicinity of the surface. The load deformation curves for these ionic single crystals show an initial region of very low slope which proved to be due to anelastic deformation. The extent of initial anelastic deformation is modified by specimen pretreatment in a way that suggests that this deformation is the result of expansion of cleaved-in dislocation loops, which can contract on the removal of the stress. The effects of the various pretreatments on the load and deflection at fracture are in accord with the prediction one might make with regard to their effect on the nucleation of fatal surface cracks. For NaCl, increases in ductility are always accompanied by increases in strength. The creep constants for NaCl are a function of treatments which affect the bulk structure but are not a function of treatments which only affect the surface.

  9. Four Weeks of Balance Training does not Affect Ankle Joint Stiffness in Subjects with Unilateral Chronic Ankle Instability

    PubMed Central

    Jain, Tarang Kumar; Wauneka, Clayton N.; Liu, Wen

    2016-01-01

    Background Balance training has been shown to be effective in preventing ankle sprain recurrences in subjects with chronic ankle instability (CAI) but the biomechanical pathways underlying the clinical outcomes are still unknown. This study was conducted to determine if a 4-week balance training intervention can alter the mechanical characteristics in ankles with CAI. Methods Twenty-two recreationally active subjects with unilateral CAI were randomized to either a control (n = 11, 35.1 ± 9.3 years) or intervention (n = 11, 33.5 ± 6.6 years) group. Subjects in the intervention group were trained on the affected limb with static and dynamic components using a Biodex balance stability system for 4-weeks. The ankle joint stiffness and neutral zone in inversion and eversion directions on the involved and uninvolved limbs was measured at baseline and post-intervention using a dynamometer. Results At baseline, the mean values of the inversion stiffness (0.69 ± 0.37 Nm/degree) in the involved ankle was significantly lower (p < 0.011, 95% CI [0.563, 0.544]) than that of uninvolved contralateral ankle (0.99 ± 0.41 Nm/degree). With the available sample size, the eversion stiffness, inversion neutral zone, and eversion neutral zone were not found to be significantly different between the involved and uninvolved contralateral ankles. The 4-week balance training intervention failed to show any significant effect on the passive ankle stiffness and neutral zones in inversion and eversion. Conclusion Decreased inversion stiffness in the involved chronic unstable ankle was found that of uninvolved contralateral ankle. The 4-week balance training program intervention was ineffective in altering the mechanical characteristics of ankles with CAI. Level of evidence Randomized controlled clinical trial; Level of evidence, 1.

  10. Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction.

    PubMed

    Grillo, Claudia A; Piroli, Gerardo G; Evans, Ashlie N; Macht, Victoria A; Wilson, Steven P; Scott, Karen A; Sakai, Randall R; Mott, David D; Reagan, Lawrence P

    2011-08-01

    Epidemiological studies estimate that greater than 60% of the adult US population may be categorized as either overweight or obese and there is a growing appreciation that obesity affects the functional integrity of the central nervous system (CNS). We recently developed a lentivirus (LV) vector that produces an insulin receptor (IR) antisense RNA sequence (IRAS) that when injected into the hypothalamus selectively decreases IR signaling in hypothalamus, resulting in increased body weight, peripheral adiposity and plasma leptin levels. To test the hypothesis that this obesity/hyperleptinemic phenotype would impair hippocampal synaptic transmission, we examined short term potentiation (STP) and long term potentiation (LTP) in the hippocampus of rats that received the LV-IRAS construct or the LV-Control construct in the hypothalamus (hypo-IRAS and hypo-Con, respectively). Stimulation of the Schaffer collaterals elicits STP that develops into LTP in the CA1 region of hypo-Con rats; conversely, hypo-IRAS rats exhibit STP that fails to develop into LTP. To more closely examine the potential role of hyperleptinemia in these electrophysiological deficits, hypo-IRAS were subjected to mild food restriction paradigms that would either: 1) prevent the development of the obesity phenotype; or 2) reverse an established obesity phenotype in hypo-IRAS rats. Both of these paradigms restored LTP in the CA1 region and reversed the decreases in the phosphorylated/total ratio of GluA1 Ser845 AMPA receptor subunit expression observed in the hippocampus of hypo-IRAS rats. Collectively, these data support the hypothesis that obesity impairs hippocampal synaptic transmission and support the hypothesis that these deficits are mediated through the impairment of hippocampal leptin activity. PMID:21036186

  11. Prenatal Hypoxia in Different Periods of Embryogenesis Differentially Affects Cell Migration, Neuronal Plasticity, and Rat Behavior in Postnatal Ontogenesis.

    PubMed

    Vasilev, Dmitrii S; Dubrovskaya, Nadezhda M; Tumanova, Natalia L; Zhuravin, Igor A

    2016-01-01

    cortical cytoarchitecture, neuronal plasticity and behavior in postnatal ontogenesis which testify to cortical dysfunction. Hypoxia on E18 does not significantly affect cortical structure and parietal cortex-dependent behavioral tasks. PMID:27065788

  12. Will the Location of the Perturbation Boundary Affect the Growth Rate of the Kelvin-Helmholtz Instability?

    NASA Astrophysics Data System (ADS)

    Chang, Yi-Wei; Lyu, Ling-Hsiao

    2016-04-01

    During the northward interplanetary magnetic field (IMF), Kelvin-Helmholtz (K-H) instability plays an important role in the mass transport at the flank magnetopause. Previous analytic study of K-H instability showed that, for a given subsonic Mach number, the growth rate varies with wavelength but is independent of the location of the perturbation boundary. In this study, we examine the growth rate of the K-H instability as a function of Mach number, the wavelength of the surface wave, and the location of the perturbation boundary. The main results are summarized as follows: (1) The growth rate of the most unstable mode of a given subsonic Mach number increases with increasing the location of the perturbation boundary. (2) No unstable mode can be found when the location of the perturbation boundary is much greater than half of the wavelength of the surface wave. (3) The growth rate of the K-H instability could remain constant if the wavelength of the surface wave increases with increasing the location of the perturbation boundary.

  13. Bacterial Genome Instability

    PubMed Central

    Darmon, Elise

    2014-01-01

    SUMMARY Bacterial genomes are remarkably stable from one generation to the next but are plastic on an evolutionary time scale, substantially shaped by horizontal gene transfer, genome rearrangement, and the activities of mobile DNA elements. This implies the existence of a delicate balance between the maintenance of genome stability and the tolerance of genome instability. In this review, we describe the specialized genetic elements and the endogenous processes that contribute to genome instability. We then discuss the consequences of genome instability at the physiological level, where cells have harnessed instability to mediate phase and antigenic variation, and at the evolutionary level, where horizontal gene transfer has played an important role. Indeed, this ability to share DNA sequences has played a major part in the evolution of life on Earth. The evolutionary plasticity of bacterial genomes, coupled with the vast numbers of bacteria on the planet, substantially limits our ability to control disease. PMID:24600039

  14. Parent-of-origin genetic background affects the transcriptional levels of circadian and neuronal plasticity genes following sleep loss

    PubMed Central

    Tinarelli, Federico; Garcia-Garcia, Celina; Nicassio, Francesco; Tucci, Valter

    2014-01-01

    Sleep homoeostasis refers to a process in which the propensity to sleep increases as wakefulness progresses and decreases as sleep progresses. Sleep is tightly organized around the circadian clock and is regulated by genetic and epigenetic mechanisms. The homoeostatic response of sleep, which is classically triggered by sleep deprivation, is generally measured as a rebound effect of electrophysiological measures, for example delta sleep. However, more recently, gene expression changes following sleep loss have been investigated as biomarkers of sleep homoeostasis. The genetic background of an individual may affect this sleep-dependent gene expression phenotype. In this study, we investigated whether parental genetic background differentially modulates the expression of genes following sleep loss. We tested the progeny of reciprocal crosses of AKR/J and DBA/2J mouse strains and we show a parent-of-origin effect on the expression of circadian, sleep and neuronal plasticity genes following sleep deprivation. Thus, we further explored, by in silico, specific functions or upstream mechanisms of regulation and we observed that several upstream mechanisms involving signalling pathways (i.e. DICER1, PKA), growth factors (CSF3 and BDNF) and transcriptional regulators (EGR2 and ELK4) may be differentially modulated by parental effects. This is the first report showing that a behavioural manipulation (e.g. sleep deprivation) in adult animals triggers specific gene expression responses according to parent-of-origin genomic mechanisms. Our study suggests that the same mechanism may be extended to other behavioural domains and that the investigation of gene expression following experimental manipulations should take seriously into account parent-of-origin effects. PMID:24446504

  15. Can high pressure I-II transitions in semiconductors be affected by plastic flow and nanocrystal precipitation in phase I?

    NASA Astrophysics Data System (ADS)

    Weinstein, B. A.; Lindberg, G. P.

    Pressure-Raman spectroscopy in ZnSe and ZnTe single crystals reveals that Se and Te nano-crystals (NCs) precipitate in these II-VI hosts for pressures far below their I-II phase transitions. The inclusions are evident from the appearance and negative pressure-shift of the A1 Raman peaks of Se and Te (trigonal phase). The Se and Te NCs nucleate at dislocations and grain boundaries that arise from pressure-induced plastic flow. This produces chemical and structural inhomogeneities in the zincblende phase of the host. At substantially higher pressures, the I-II transition proceeds in the presence of these inhomogenities. This can affect the transition's onset pressure Pt and width ΔPt, and the occurrence of metastable phases along the transition path. Precipitation models in metals show that nucleation of inclusions depends on the Peierls stress τp and a parameter α related to the net free energy gained on nucleation. For favorable values of τp and α, NC precipitation at pressures below the I-II transition could occur in other compounds. We propose criteria to judge whether this is likely based on the observed ranges of τp in the hosts, and estimates of α derived from the cohesive energy densities of the NC materials. One finds trends that can serve as a useful guide, both to test the proposed criteria, and to decide when closer scrutiny of phase transition experiments is warranted, e.g., in powders where high dislocation densities are initially created

  16. Mechanisms of Plastic and Fracture Instabilities for Alloy Development of Fusion Materials. Final Project Report for period July 15, 1998 - July 14, 2003

    SciTech Connect

    Ghoniem, N. M.

    2003-07-14

    The main objective of this research was to develop new computational tools for the simulation and analysis of plasticity and fracture mechanisms of fusion materials, and to assist in planning and assessment of corresponding radiation experiments.

  17. Metaplasticity and behavior: how training and inflammation affect plastic potential within the spinal cord and recovery after injury

    PubMed Central

    Grau, James W.; Huie, J. Russell; Lee, Kuan H.; Hoy, Kevin C.; Huang, Yung-Jen; Turtle, Joel D.; Strain, Misty M.; Baumbauer, Kyle M.; Miranda, Rajesh M.; Hook, Michelle A.; Ferguson, Adam R.; Garraway, Sandra M.

    2014-01-01

    Research has shown that spinal circuits have the capacity to adapt in response to training, nociceptive stimulation and peripheral inflammation. These changes in neural function are mediated by physiological and neurochemical systems analogous to those that support plasticity within the hippocampus (e.g., long-term potentiation and the NMDA receptor). As observed in the hippocampus, engaging spinal circuits can have a lasting impact on plastic potential, enabling or inhibiting the capacity to learn. These effects are related to the concept of metaplasticity. Behavioral paradigms are described that induce metaplastic effects within the spinal cord. Uncontrollable/unpredictable stimulation, and peripheral inflammation, induce a form of maladaptive plasticity that inhibits spinal learning. Conversely, exposure to controllable or predictable stimulation engages a form of adaptive plasticity that counters these maladaptive effects and enables learning. Adaptive plasticity is tied to an up-regulation of brain derived neurotrophic factor (BDNF). Maladaptive plasticity is linked to processes that involve kappa opioids, the metabotropic glutamate (mGlu) receptor, glia, and the cytokine tumor necrosis factor (TNF). Uncontrollable nociceptive stimulation also impairs recovery after a spinal contusion injury and fosters the development of pain (allodynia). These adverse effects are related to an up-regulation of TNF and a down-regulation of BDNF and its receptor (TrkB). In the absence of injury, brain systems quell the sensitization of spinal circuits through descending serotonergic fibers and the serotonin 1A (5HT 1A) receptor. This protective effect is blocked by surgical anesthesia. Disconnected from the brain, intracellular Cl- concentrations increase (due to a down-regulation of the cotransporter KCC2), which causes GABA to have an excitatory effect. It is suggested that BDNF has a restorative effect because it up-regulates KCC2 and re-establishes GABA-mediated inhibition

  18. Preventive brain radio-chemotherapy alters plasticity associated metabolite profile in the hippocampus but seems to not affect spatial memory in young leukemia patients

    PubMed Central

    Brandt, Moritz D; Brandt, Kalina; Werner, Annett; Schönfeld, Robby; Loewenbrück, Kai; Donix, Markus; Schaich, Markus; Bornhäuser, Martin; von Kummer, Rüdiger; Leplow, Bernd; Storch, Alexander

    2015-01-01

    Background Neuronal plasticity leading to evolving reorganization of the neuronal network during entire lifespan plays an important role for brain function especially memory performance. Adult neurogenesis occurring in the dentate gyrus of the hippocampus represents the maximal way of network reorganization. Brain radio-chemotherapy strongly inhibits adult hippocampal neurogenesis in mice leading to impaired spatial memory. Methods To elucidate the effects of CNS radio-chemotherapy on hippocampal plasticity and function in humans, we performed a longitudinal pilot study using 3T proton magnetic resonance spectroscopy (1H-MRS) and virtual water-maze-tests in 10 de-novo patients with acute lymphoblastic leukemia undergoing preventive whole brain radio-chemotherapy. Patients were examined before, during and after treatment. Results CNS radio-chemotherapy did neither affect recall performance in probe trails nor flexible (reversal) relearning of a new target position over a time frame of 10 weeks measured by longitudinal virtual water-maze-testing, but provoked hippocampus-specific decrease in choline as a metabolite associated with cellular plasticity in 1H-MRS. Conclusion Albeit this pilot study needs to be followed up to definitely resolve the question about the functional role of adult human neurogenesis, the presented data suggest that 1H-MRS allows the detection of neurogenesis-associated plasticity in the human brain. PMID:26442754

  19. Repeated Three-Hour Maternal Separation Induces Depression-Like Behavior and Affects the Expression of Hippocampal Plasticity-Related Proteins in C57BL/6N Mice

    PubMed Central

    Bian, Yaoyao; Yang, Lili; Wang, Zhongli; Wang, Qing; Zeng, Li; Xu, Guihua

    2015-01-01

    Adverse early life experiences can negatively affect behaviors later in life. Maternal separation (MS) has been extensively investigated in animal models in the adult phase of MS. The study aimed to explore the mechanism by which MS negatively affects C57BL/6N mice, especially the effects caused by MS in the early phase. Early life adversity especially can alter plasticity functions. To determine whether adverse early life experiences induce changes in plasticity in the brain hippocampus, we established an MS paradigm. In this research, the mice were treated with mild (15 min, MS15) or prolonged (180 min, MS180) maternal separation from postnatal day 2 to postnatal day 21. The mice underwent a forced swimming test, a tail suspension test, and an open field test, respectively. Afterward, the mice were sacrificed on postnatal day 31 to determine the effects of MS on early life stages. Results implied that MS induces depression-like behavior and the effects may be mediated partly by interfering with the hippocampal GSK-3β-CREB signaling pathway and by reducing the levels of some plasticity-related proteins. PMID:26798520

  20. Plastic hatching timing by red-eyed treefrog embryos interacts with larval predator identity and sublethal predation to affect prey morphology but not performance.

    PubMed

    Touchon, Justin C; Wojdak, Jeremy M

    2014-01-01

    Many animals respond to predation risk by altering their morphology, behavior, or life-history. We know a great deal about the cues prey respond to and the changes to prey that can be induced by predation risk, but less is known about how plastic responses to predators may be affected by separate plastic responses occurring earlier in life, particularly during the embryonic period. Embryos of a broad array of taxa can respond to egg- or larval-stage risks by altering hatching timing, which may alter the way organisms respond to future predators. Using the red-eyed treefrog (Agalychnis callidryas), a model for understanding the effects of plasticity across life-stages, we assessed how the combined effects of induced variation in the timing of embryo hatching and variation in the larval predator community impacted tadpole morphology, pigmentation and swimming performance. We found that A. callidryas tadpoles developed deeper tail muscles and fins and darker pigmentation in response to fish predators, either when alone or in diverse community with other predators. Tadpoles altered morphology much less so to dragonfly naiads or water bugs. Interestingly, morphological responses to predators were also affected by induced differences in hatching age, with early and late-hatched tadpoles exhibiting different allometric relationships between tail height and body length in different predator environments. Beyond induced morphological changes, fish predators often damaged tadpoles' tails without killing them (i.e., sublethal predation), but these tadpoles swam equally quickly to those with fully intact tails. This was due to the fact that tadpoles with more damaged tails increased tail beats to achieve equal swimming speed. This study demonstrates that plastic phenotypic responses to predation risk can be influenced by a complex combination of responses to both the embryo and larval environments, but also that prey performance can be highly resilient to sublethal predation

  1. Plastic Hatching Timing by Red-Eyed Treefrog Embryos Interacts with Larval Predator Identity and Sublethal Predation to Affect Prey Morphology but Not Performance

    PubMed Central

    Touchon, Justin C.; Wojdak, Jeremy M.

    2014-01-01

    Many animals respond to predation risk by altering their morphology, behavior, or life-history. We know a great deal about the cues prey respond to and the changes to prey that can be induced by predation risk, but less is known about how plastic responses to predators may be affected by separate plastic responses occurring earlier in life, particularly during the embryonic period. Embryos of a broad array of taxa can respond to egg- or larval-stage risks by altering hatching timing, which may alter the way organisms respond to future predators. Using the red-eyed treefrog (Agalychnis callidryas), a model for understanding the effects of plasticity across life-stages, we assessed how the combined effects of induced variation in the timing of embryo hatching and variation in the larval predator community impacted tadpole morphology, pigmentation and swimming performance. We found that A. callidryas tadpoles developed deeper tail muscles and fins and darker pigmentation in response to fish predators, either when alone or in diverse community with other predators. Tadpoles altered morphology much less so to dragonfly naiads or water bugs. Interestingly, morphological responses to predators were also affected by induced differences in hatching age, with early and late-hatched tadpoles exhibiting different allometric relationships between tail height and body length in different predator environments. Beyond induced morphological changes, fish predators often damaged tadpoles’ tails without killing them (i.e., sublethal predation), but these tadpoles swam equally quickly to those with fully intact tails. This was due to the fact that tadpoles with more damaged tails increased tail beats to achieve equal swimming speed. This study demonstrates that plastic phenotypic responses to predation risk can be influenced by a complex combination of responses to both the embryo and larval environments, but also that prey performance can be highly resilient to sublethal predation

  2. Tensile Elastic Properties of Typical Stainless Steels and Nonferrous Metals as Affected by Plastic Deformation and by Heat Treatment

    NASA Technical Reports Server (NTRS)

    Mcadam, D J; Mebs, R W

    1940-01-01

    A general discussion is given of the relationships between stress, strain, and permanent set. From stress-set curves are derived proof stresses based on five different percentages of permanent set. The influence of prior plastic extension on these values is illustrated and discussed. A discussion is given of the influence of work-hardening, rest interval, and internal stress on the form of the proof stress-extension curve.

  3. Ovarian cycle-linked plasticity of δ-GABAA receptor subunits in hippocampal interneurons affects γ oscillations in vivo.

    PubMed

    Barth, Albert M I; Ferando, Isabella; Mody, Istvan

    2014-01-01

    GABAA receptors containing δ subunits (δ-GABAARs) are GABA-gated ion channels with extra- and perisynaptic localization, strong sensitivity to neurosteroids (NS), and a high degree of plasticity. In selective brain regions they are expressed on specific principal cells and interneurons (INs), and generate a tonic conductance that controls neuronal excitability and oscillations. Plasticity of δ-GABAARs in principal cells has been described during states of altered NS synthesis including acute stress, puberty, ovarian cycle, pregnancy and the postpartum period, with direct consequences on neuronal excitability and network dynamics. The defining network events implicated in cognitive function, memory formation and encoding are γ oscillations (30-120 Hz), a well-timed loop of excitation and inhibition between principal cells and PV-expressing INs (PV + INs). The δ-GABAARs of INs can modify γ oscillations, and a lower expression of δ-GABAARs on INs during pregnancy alters γ frequency recorded in vitro. The ovarian cycle is another physiological event with large fluctuations in NS levels and δ-GABAARs. Stages of the cycle are paralleled by swings in memory performance, cognitive function, and mood in both humans and rodents. Here we show δ-GABAARs changes during the mouse ovarian cycle in hippocampal cell types, with enhanced expression during diestrus in principal cells and specific INs. The plasticity of δ-GABAARs on PV-INs decreases the magnitude of γ oscillations continuously recorded in area CA1 throughout several days in vivo during diestrus and increases it during estrus. Such recurring changes in γ magnitude were not observed in non-cycling wild-type (WT) females, cycling females lacking δ-GABAARs only on PV-INs (PV-Gabrd (-/-)), and in male mice during a time course equivalent to the ovarian cycle. Our findings may explain the impaired memory and cognitive performance experienced by women with premenstrual syndrome (PMS) or premenstrual dysphoric

  4. Cyclic loading of an elastic-plastic adhesive spherical microcontact

    NASA Astrophysics Data System (ADS)

    Kadin, Y.; Kligerman, Y.; Etsion, I.

    2008-10-01

    A previous study of a single load-unload cycle of an adhesive contact between an elastic-plastic microscopic sphere and a rigid flat is extended here for several load-unload cycles. The interacting forces between the sphere and the flat obey the Lennard-Jones potential. Kinematic hardening is assumed for the sphere material to account for possible plastic shakedown, and the difference between kinematic and isotropic hardenings is discussed. The main goal of the current work is to investigate the evolution of the load-approach curves for the elastic-plastic spherical contact during its cyclic loading-unloading. These curves are presented for different physical conditions, represented by three main dimensionless parameters, which affect the behavior of the elastic-plastic adhesive contact. A transition value of the Tabor parameter is found, below which the load-approach curves are always continuous and jump-in and jump-out instabilities are not expected.

  5. Does Carbopol Elasticity affect its Yielding Dynamics? A study based on the Settling of a Particle in ``Plastic'' materials

    NASA Astrophysics Data System (ADS)

    Fraggedakis, Dimitris; Dimakopoulos, Yiannis; Tsamopoulos, John

    2015-11-01

    For several decades, Carbopol is assumed to be the ideal plastic material, exhibiting only yield phenomena without viscoelastic effects in yielded regions. Recently, it has been shown that when stresses do not overcome the yield criterion, it behaves as an ideal Hookean solid, Piau (2007). Also, experiments (Putz et al. (2006); Holenberg et al. (2012)) reveal phenomena which can be attributed only to elastic properties of the fluidized region, such as the appearance of the so-called ``negative wake,'' Harlen (2002), downstream the sphere and the loss of fore-aft symmetry of the yield surface around a sedimenting particle. Our study is based on the sedimentation of a confined particle in materials which exhibit elastoviscoplastic behavior and proves that Carbopol cannot be considered as the ideal plastic material anymore. Moreover, when elasticity comes into play, the derived stoppage criterion for a sedimenting sphere by Beris et al. (1985) and experimentally confirmed by Tabuteau et al. (2007) is not satisfied, as a complex stress field is developed around the particle and fluidization near the rigid surface is favored. The existence of the yield surface near the sphere enhances the formation of shear layers, which are responsible for the formation of the negative wake, irrespectively of the position of the confinement in relation to the sphere. GSRT Greece-Israel bilateral projects PHARMAMUDS #3163.

  6. Biodegradability of Plastics

    PubMed Central

    Tokiwa, Yutaka; Calabia, Buenaventurada P.; Ugwu, Charles U.; Aiba, Seiichi

    2009-01-01

    Plastic is a broad name given to different polymers with high molecular weight, which can be degraded by various processes. However, considering their abundance in the environment and their specificity in attacking plastics, biodegradation of plastics by microorganisms and enzymes seems to be the most effective process. When plastics are used as substrates for microorganisms, evaluation of their biodegradability should not only be based on their chemical structure, but also on their physical properties (melting point, glass transition temperature, crystallinity, storage modulus etc.). In this review, microbial and enzymatic biodegradation of plastics and some factors that affect their biodegradability are discussed. PMID:19865515

  7. Colored light-quality selective plastic films affect anthocyanin content, enzyme activities, and the expression of flavonoid genes in strawberry (Fragaria × ananassa) fruit.

    PubMed

    Miao, Lixiang; Zhang, Yuchao; Yang, Xiaofang; Xiao, Jinping; Zhang, Huiqin; Zhang, Zuofa; Wang, Yuezhi; Jiang, Guihua

    2016-09-15

    The influence of colored light-quality selective plastic films (red, yellow, green, blue, and white) on the content of anthocyanin, the activities of the related enzymes and the transcripts of the flavonoid gene was studied in developing strawberry fruit. The results indicated that colored films had highly significant effects on the total anthocyanin content (TAC) and proportions of individual anthocyanins. Compared with the white control film, the red and yellow films led to the significant increase of TAC, while the green and blue films caused a decrease of TAC. Colored film treatments also significantly affected the related enzyme activity and the expression of structural genes and transcription factor genes, which suggested that the enhancement of TAC by the red and yellow films might have resulted from the activation of related enzymes and transcription factor genes in the flavonoid pathway. Treatment with red and yellow light-quality selective plastic films might be useful as a supplemental cultivation practice for enhancing the anthocyanin content in developing strawberry fruit. PMID:27080884

  8. Shoulder Instability

    MedlinePlus

    ... Risk Factors Is shoulder instability the same as shoulder dislocation? No. The signs of dislocation and instability might ... the same to you--weakness and pain. However, dislocation occurs when your shoulder goes completely out of place. The shoulder ligaments ...

  9. 40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 13 2012-07-01 2012-07-01 false How do I know if my reinforced plastic... Emissions Standards for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new...

  10. 40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 13 2013-07-01 2012-07-01 true How do I know if my reinforced plastic... Emissions Standards for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new...

  11. 40 CFR 63.5795 - How do I know if my reinforced plastic composites production facility is a new affected source or...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 13 2014-07-01 2014-07-01 false How do I know if my reinforced plastic... Emissions Standards for Hazardous Air Pollutants: Reinforced Plastic Composites Production What This Subpart Covers § 63.5795 How do I know if my reinforced plastic composites production facility is a new...

  12. Rotor internal friction instability

    NASA Technical Reports Server (NTRS)

    Bently, D. E.; Muszynska, A.

    1985-01-01

    Two aspects of internal friction affecting stability of rotating machines are discussed. The first role of internal friction consists of decreasing the level of effective damping during rotor subsynchronous and backward precessional vibrations caused by some other instability mechanisms. The second role of internal frication consists of creating rotor instability, i.e., causing self-excited subsynchronous vibrations. Experimental test results document both of these aspects.

  13. Plastic Surgery

    MedlinePlus

    ... How Can I Help a Friend Who Cuts? Plastic Surgery KidsHealth > For Teens > Plastic Surgery Print A ... her forehead lightened with a laser? What Is Plastic Surgery? Just because the name includes the word " ...

  14. Congenital absence of corticospinal tract does not severely affect plastic changes of the developing postnatal spinal cord.

    PubMed

    Huang, L; Xian, Q; Shen, N; Shi, L; Qu, Y; Zhou, L

    2015-08-20

    The arrival and refinement of corticospinal afferents are likely to influence the maturation of the spinal cord and sensory-motor networks. To understand this better, we studied the revision of monosynaptic muscle afferents, the expression of activity-related genes, neurotrophins and their receptors in the cervical spinal cord from postnatal day (P) 0 to 21. We compared control and Celsr3|Emx1 mice, in which corticospinal axons never develop. The corticospinal tract (CST), labeled by anti-protein kinase C gamma (PKCγ) antibody in the dorsal funiculus, increased gradually in the control, but was never visible in the mutant. Using anti-parvalbumin and choline acetyltransferase double immunostaining, close contacts between proprioceptive afferent fibers and spinal motor neurons appeared at P0 and were gradually eliminated thereafter, with no difference between control and mutant mice. In both genotypes, the number of parvalbumin-positive interneurons increased similarly from P7 to P21, and a comparable upregulation of c-Jun protein was seen at P7. Contrary to control samples, in which ciliary neurotrophic factor (CNTF) protein levels increased from P0 to P7 and gradually decreased after P14, CNTF concentrations were time-invariant in mutant samples. The dynamic profile of neurotrophin-3 (NT3) expression was also moderately affected in mutant mice. In control spinal cord, NT3 was increased at P7 and decreased at P14, but remained more stable in mutant samples. In contrast, expression profiles of brain-derived neurotrophic factor (BDNF), tropomyosin-related kinase (Trk) B, TrkC, p75 neurotrophin receptor (p75(NTR)) and glial cell-line-derived neurotrophic factor (GDNF) were similar in both genotypes. In conclusion, with the possible exception of CNTF and NT3 expression, most events that accompany maturation of the spinal cord appear largely independent of corticospinal inputs. PMID:26079333

  15. Gestational stress and fluoxetine treatment differentially affect plasticity, methylation and serotonin levels in the PFC and hippocampus of rat dams.

    PubMed

    Gemmel, Mary; Rayen, Ine; van Donkelaar, Eva; Loftus, Tiffany; Steinbusch, Harry W; Kokras, Nikolaos; Dalla, Christina; Pawluski, Jodi L

    2016-07-01

    Women are more likely to develop depression during childbearing years with up to 20% of women suffering from depression during pregnancy and in the postpartum period. Increased prevalence of depression during the perinatal period has resulted in frequent selective serotonin reuptake inhibitor (SSRI) antidepressant treatment; however the effects of such medications on the maternal brain remain limited. Therefore, the aim of the present study is to investigate the effects of the SSRI medication, fluoxetine, on neurobiological differences in the maternal brain. To model aspects of maternal depression, gestational stress was used. Sprague-Dawley rat dams were exposed to either gestational stress and/or fluoxetine (5mg/kg/day) to form the following four groups: 1. Control+Vehicle, 2. Stress+Vehicle, 3. Control+Fluoxetine, and 4. Stress+Fluoxetine. At weaning maternal brains were collected. Main findings show that gestational stress alone increased synaptophysin and serotonin metabolism in the cingulate cortex2 region of the cortex while fluoxetine treatment after stress normalized these effects. In the hippocampus, fluoxetine treatment, regardless of gestational stress exposure, decreased both global measures of methylation in the dentate gyrus, as measured by Dnmt3a immunoreactivity, as well as serotonin metabolism. No further changes in synaptophysin, PSD-95, or Dnmt3a immunoreactivity were seen in the cortical or hippocampal areas investigated. These findings show that gestational stress and SSRI medication affect the neurobiology of the maternal brain in a region-specific manner. This work adds to a much needed area of research aimed at understanding neurobiological changes associated with maternal depression and the role of SSRI treatment in altering these changes in the female brain. PMID:27060483

  16. Collective instabilities

    SciTech Connect

    K.Y. Ng

    2003-08-25

    The lecture covers mainly Sections 2.VIII and 3.VII of the book ''Accelerator Physics'' by S.Y. Lee, plus mode-coupling instabilities and chromaticity-driven head-tail instability. Besides giving more detailed derivation of many equations, simple interpretations of many collective instabilities are included with the intention that the phenomena can be understood more easily without going into too much mathematics. The notations of Lee's book as well as the e{sup jwt} convention are followed.

  17. Vortex Plastic Flow in Superconductors: Computing and Visualizing Dynamical Instabilities, Flux Cascades, Voltage Bursts, and the Derivation of Macroscopic Magnetic Quantities from the Microscopic Dynamics of Individual Flux Lines

    NASA Astrophysics Data System (ADS)

    Nori, Franco

    1996-03-01

    Computer simulations can be a valuable tool for the analysis of the microscopic spatio-temporal dynamics of individual flux-lines in superconductors, lending insight to commonly measured bulk macroscopic quantities such as magnetization and critical currents. We have performed(In collaboration with C. Reichhardt, C.J. Olson, J. Groth, and S. Field, Phys. Rev. B 52), 10441 (1995); and preprints. extensive MD simulations of flux-gradient-driven flux lines (i.e., there is no artificial uniform external force on the vortices) as an external field H(t) is quasi-statically ramped up and down. We explore a wide variety of relevant parameters which are difficult to continuously tune experimentally, such as the density, strength, radius, and location of the pinning sites. We find a rich variety of behavior in which all these parameters play an important role. Our predictions (e.g., magnetization hysteresis loops) can be directly compared with commonly-measured experimental quantities. Among others, we study in detail samples (i) with twin boundaries, (ii) with a periodic array of pinning sites, (iii) in the Bose glass regime. We analyze both global (e.g., M(H), J_c(H)) and local (e.g., B(x,y,H(t)), M(x,y,H(t)), J_c(x,y,B)) measurable quantities. Our results elucidate the topological order dynamics of a driven plastic lattice interacting with a rigid disordered substrate, a problem that has recently attracted considerable attention. We characterize, and illustrate with a color video, dynamical instabilities (i.e., flux cascades, voltage bursts), as well as the evolution of the topological order and vortex flow paths (``vortex streets" surrounded by regions of pinned flux).

  18. How Plastics Work

    NASA Astrophysics Data System (ADS)

    Bloomfield, Louis

    2013-03-01

    We encounter plastics every day, but despite their widespread use, amazing range of properties, and basic scientific underpinnings, most physicists--like most people--know relatively little about plastics. In contrast to hard crystalline and amorphous solids (e.g., metals, salts, ceramics, and glasses), we take plastics for granted, select them carelessly, and examine them more closely only on a need-to-know basis. By ignoring plastics until we need them, however, we risk not knowing what we don't know and using the wrong ones. To repurpose a familiar advertisement, ``there's a plastic for that.'' This talk will review some of the basic physics and science of plastics. It will examine the roles of temperature, order, intermolecular forces, entanglements, and linkages in plastics, and how those issues affect the properties of a given plastic. We'll stop along the way to recognize a few of the more familiar plastics, natural and synthetic, and explain some of their mechanical, chemical, and optical properties. The talk will conclude by explaining the remarkable properties of a plastic that has been largely misunderstood since its discovery 70 years ago: Silly Putty.

  19. Plastic Jellyfish.

    ERIC Educational Resources Information Center

    Moseley, Christine

    2000-01-01

    Presents an environmental science activity designed to enhance students' awareness of the hazards of plastic waste for wildlife in aquatic environments. Discusses how students can take steps to reduce the effects of plastic waste. (WRM)

  20. Micromechanics of nonlinear plastic modes

    NASA Astrophysics Data System (ADS)

    Lerner, Edan

    2016-05-01

    Nonlinear plastic modes (NPMs) are collective displacements that are indicative of imminent plastic instabilities in elastic solids. In this work we formulate the atomistic theory that describes the reversible evolution of NPMs and their associated stiffnesses under external deformations. The deformation dynamics of NPMs is compared to those of the analogous observables derived from atomistic linear elastic theory, namely, destabilizing eigenmodes of the dynamical matrix and their associated eigenvalues. The key result we present and explain is that the dynamics of NPMs and of destabilizing eigenmodes under external deformations follow different scaling laws with respect to the proximity to imminent instabilities. In particular, destabilizing modes vary with a singular rate, whereas NPMs exhibit no such singularity. As a result, NPMs converge much earlier than destabilizing eigenmodes to their common final form at plastic instabilities. This dynamical difference between NPMs and linear destabilizing eigenmodes underlines the usefulness of NPMs for predicting the locus and geometry of plastic instabilities, compared to their linear-elastic counterparts.

  1. Rayleigh-Taylor and Richtmyer-Meshkov Instabilities in Turbulent Regime

    NASA Astrophysics Data System (ADS)

    Dimonte, G.

    1998-11-01

    The Rayleigh-Taylor instability (RTI) and its shock driven analog, the Richtmyer-Meshkov instability (RMI), affect a wide variety of important phenomena from sub-terrainian to astrophysical environments. The ``fluids" are equally varied from plasmas and magnetic fields to elastic-plastic solids. In most applications, the instabilities occur with a complex acceleration history and evolve to a highly nonlinear state, making the theoretical description formidable. We will link the fluid and plasma regimes while describing the theoretical issues and basic experiments in different venues to isolate key physics issues. RMI experiments on the Nova laser investigate the affects of compressibility with strong radiatively driven shocks (Mach > 10) in near solid density plasmas of sub-millimeter scale. The growth of single sinusoidal and random 3-D perturbations are measured using backlit radiography. RTI experiments with the Linear Electric Motor (LEM) are conducted with a variety of acceleration (<< 10^4 m/s^2) histories and fluids of 10 cm scale. Turbulent RTI experiments with high Reynolds number liquids show self-similar growth which is characterized with laser induced fluorescence. LEM experiments with an elastic-plastic material (yogurt) exhibit a critical wavelength and amplitude for instability. The experimental results will be compared with linear and nonlinear theories and hydrodynamic simulations.

  2. A numerical and analytical investigation of Rayleigh-Taylor instability in a solid tungsten plate

    SciTech Connect

    Robinson, A.C.; Swegle, J.W.

    1987-07-01

    The Rayleigh-Taylor instability response of an elastic-plastic tungsten plate is investigated by numerical experiments and an approximate modal analysis. The so-called ''minimum amplitude'' instability criteria derived from plasticity analyses is shown to be incomplete as a general indicator of instability or stability at very large driving pressures. Model equations are derived which are able to reproduce the basic qualitative features of the observed instability response given by the numerical calculations. 11 refs., 29 figs.

  3. Individual differences in behavioural plasticities.

    PubMed

    Stamps, Judy A

    2016-05-01

    Interest in individual differences in animal behavioural plasticities has surged in recent years, but research in this area has been hampered by semantic confusion as different investigators use the same terms (e.g. plasticity, flexibility, responsiveness) to refer to different phenomena. The first goal of this review is to suggest a framework for categorizing the many different types of behavioural plasticities, describe examples of each, and indicate why using reversibility as a criterion for categorizing behavioural plasticities is problematic. This framework is then used to address a number of timely questions about individual differences in behavioural plasticities. One set of questions concerns the experimental designs that can be used to study individual differences in various types of behavioural plasticities. Although within-individual designs are the default option for empirical studies of many types of behavioural plasticities, in some situations (e.g. when experience at an early age affects the behaviour expressed at subsequent ages), 'replicate individual' designs can provide useful insights into individual differences in behavioural plasticities. To date, researchers using within-individual and replicate individual designs have documented individual differences in all of the major categories of behavioural plasticities described herein. Another important question is whether and how different types of behavioural plasticities are related to one another. Currently there is empirical evidence that many behavioural plasticities [e.g. contextual plasticity, learning rates, IIV (intra-individual variability), endogenous plasticities, ontogenetic plasticities) can themselves vary as a function of experiences earlier in life, that is, many types of behavioural plasticity are themselves developmentally plastic. These findings support the assumption that differences among individuals in prior experiences may contribute to individual differences in behavioural

  4. DIFFUSION AND EMISSIONS OF 1,3-DICHLOROPROPENE IN FLORIDA SANDY SOIL IN MICROPLOTS AFFECTED BY SOIL MOISTURE, ORGANIC MATTER, AND PLASTIC FILM.

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The fumigant 1,3-dichloropropene (1,3-D) is a methyl bromide alternative for preplant soil treatment. The objective was to determine effects of soil water and plastic cover on dispersion and emissions of 1,3-D in a Florida soil (Arredondo fine sand). Liquid 1,3-D was injected at 30-cm depths at 8 po...

  5. Plastics Technology.

    ERIC Educational Resources Information Center

    Barker, Tommy G.

    This curriculum guide is designed to assist junior high schools industrial arts teachers in planning new courses and revising existing courses in plastics technology. Addressed in the individual units of the guide are the following topics: introduction to production technology; history and development of plastics; safety; youth leadership,…

  6. Hybrid rocket instability

    NASA Technical Reports Server (NTRS)

    Greiner, B.; Frederick, R. A., Jr.

    1993-01-01

    The paper provides a brief review of theoretical and experimental studies concerned with hybrid rocket instability. The instabilities discussed include atomization and mixing instabilities, chuffing instabilities, pressure coupled combustion instabilities, and vortex shedding. It is emphasized that the future use of hybrid motor systems as viable design alternatives will depend on a better understanding of hybrid instability.

  7. Hybrid rocket instability

    NASA Astrophysics Data System (ADS)

    Greiner, B.; Frederick, R. A., Jr.

    1993-06-01

    The paper provides a brief review of theoretical and experimental studies concerned with hybrid rocket instability. The instabilities discussed include atomization and mixing instabilities, chuffing instabilities, pressure coupled combustion instabilities, and vortex shedding. It is emphasized that the future use of hybrid motor systems as viable design alternatives will depend on a better understanding of hybrid instability.

  8. Plastic-film mulching and urea types affect soil CO2 emissions and grain yield in spring maize on the Loess Plateau, China

    PubMed Central

    Liu, Qiaofei; Chen, Yu; Li, Weiwei; Liu, Yang; Han, Juan; Wen, Xiaoxia; Liao, Yuncheng

    2016-01-01

    A 2-year field experiment was conducted on maize (Zea mays L.) to explore effective ways to decrease soil CO2 emissions and increase grain yield. Treatments established were: (1) no mulching with urea, (2) no mulching with controlled release fertiliser (CRF), (3) transparent plastic-film mulching (PMt) with urea, (4) PMt with CRF, (5) black plastic-film mulching (PMb) with urea, and (6) PMb with CRF. During the early growth stages, soil CO2 emissions were noted as PMt > PMb > no mulching, and this order was reversed in the late growth stages. This trend was the result of topsoil temperature dynamics. There were no significant correlations noted between soil CO2 emissions and soil temperature and moisture. Cumulative soil CO2 emissions were higher for the PMt than for the PMb, and grain yield was higher for the PMb treatments than for the PMt or no mulching treatments. The CRF produced higher grain yield and inhibited soil CO2 emissions. Soil CO2 emissions per unit grain yield were lower for the BC treatment than for the other treatments. In conclusion, the use of black plastic-film mulching and controlled release fertiliser not only increased maize yield, but also reduced soil CO2 emissions. PMID:27329934

  9. Plastic-film mulching and urea types affect soil CO2 emissions and grain yield in spring maize on the Loess Plateau, China.

    PubMed

    Liu, Qiaofei; Chen, Yu; Li, Weiwei; Liu, Yang; Han, Juan; Wen, Xiaoxia; Liao, Yuncheng

    2016-01-01

    A 2-year field experiment was conducted on maize (Zea mays L.) to explore effective ways to decrease soil CO2 emissions and increase grain yield. Treatments established were: (1) no mulching with urea, (2) no mulching with controlled release fertiliser (CRF), (3) transparent plastic-film mulching (PMt) with urea, (4) PMt with CRF, (5) black plastic-film mulching (PMb) with urea, and (6) PMb with CRF. During the early growth stages, soil CO2 emissions were noted as PMt > PMb > no mulching, and this order was reversed in the late growth stages. This trend was the result of topsoil temperature dynamics. There were no significant correlations noted between soil CO2 emissions and soil temperature and moisture. Cumulative soil CO2 emissions were higher for the PMt than for the PMb, and grain yield was higher for the PMb treatments than for the PMt or no mulching treatments. The CRF produced higher grain yield and inhibited soil CO2 emissions. Soil CO2 emissions per unit grain yield were lower for the BC treatment than for the other treatments. In conclusion, the use of black plastic-film mulching and controlled release fertiliser not only increased maize yield, but also reduced soil CO2 emissions. PMID:27329934

  10. Developmental instability of gynodioecious Teucrium lusitanicum

    USGS Publications Warehouse

    Alados, C.L.; Navarro, T.; Cabezudo, B.; Emlen, J.M.; Freeman, C.

    1998-01-01

    Developmental instability was assessed in two geographical races of Teucrium lusitanicum using morphometric measures of vegetative and reproductive structures. T. lusitanicum is a gynodioecious species. Male sterile (female) individuals showed greater developmental instability at all sites. Plants located inland had higher developmental instability of vegetative characters and lower developmental instability of reproductive characters than coastal plants. These results support the contentions that (1) developmental instability is affected more by the disruption of co-adapted gene complexes than by lower heterozygosity, and (2) different habitat characteristics result in the differential response of vegetative and reproductive structures.

  11. Rayleigh-Taylor instability in elastic solids.

    PubMed

    Piriz, A R; Cela, J J López; Cortázar, O D; Tahir, N A; Hoffmann, D H H

    2005-11-01

    We present an analytical model for the Rayleigh-Taylor instability that allows for an approximate but still very accurate and appealing description of the instability physics in the linear regime. The model is based on the second law of Newton and it has been developed with the aim of dealing with the instability of accelerated elastic solids. It yields the asymptotic instability growth rate but also describes the initial transient phase determined by the initial conditions. We have applied the model to solid/solid and solid/fluid interfaces with arbitrary Atwood numbers. The results are in excellent agreement with previous models that yield exact solutions but which are of more limited validity. Our model allows for including more complex physics. In particular, the present approach is expected to lead to a more general theory of the instability that would allow for describing the transition to the plastic regime. PMID:16383751

  12. Magnetohydrodynamic instability

    NASA Technical Reports Server (NTRS)

    Priest, E. R.; Cargill, P.; Forbes, T. G.; Hood, A. W.; Steinolfson, R. S.

    1986-01-01

    There have been major advances in the theory of magnetic reconnection and of magnetic instability, with important implications for the observations, as follows: (1) Fast and slow magnetic shock waves are produced by the magnetohydrodynamics of reconnection and are potential particle accelerators. (2) The impulsive bursty regime of reconnection gives a rapid release of magnetic energy in a series of bursts. (3) The radiative tearing mode creates cool filamentary structures in the reconnection process. (4) The stability analyses imply that an arcade can become unstable when either its height or twist of plasma pressure become too great.

  13. Yet another instability in glasma

    NASA Astrophysics Data System (ADS)

    Tsutsui, Shoichiro; Iida, Hideaki; Kunihiro, Teiji; Ohnishi, Akira

    2014-09-01

    In relativistic heavy ion collisions (HIC), hydrodynamic models can describe many experimental data and suggest that the quark-gluon plasma formed at RHIC and LHC is almost perfect fluid. We need very short thermalization time and far-from-equilibrium dynamics may be important in thermalization processes of HIC. In the earliest stages of HIC, classical gluon dynamics is dominant and many types of instabilities emerge there. These instabilities may strongly affect the later stages of dynamics; realization of chaoticity and field-particle conversions. We investigate instabilities of classical gluon fields under the homogeneous, but time dependent background color magnetic fields. The background field become periodic function of time and we can analyze the stability of fluctuations based on the Floquet theory which consists the basis of the Bloch theory. As a result, we get the complete structure of instability bands for physical degrees of freedom appearing from parametric resonance. We also find that the parametric instabilities considered here have different natures from the several known instabilities; Weibel and Nielsen-Olesen instabilities. We also discuss some implications of parametric resonance to the particle productions in HIC.

  14. Plastic Bronchitis.

    PubMed

    Rubin, Bruce K

    2016-09-01

    Plastic bronchitis is an uncommon and probably underrecognized disorder, diagnosed by the expectoration or bronchoscopic removal of firm, cohesive, branching casts. It should not be confused with purulent mucous plugging of the airway as seen in patients with cystic fibrosis or bronchiectasis. Few medications have been shown to be effective and some are now recognized as potentially harmful. Current research directions in plastic bronchitis research include understanding the genetics of lymphatic development and maldevelopment, determining how abnormal lymphatic malformations contribute to cast formation, and developing new treatments. PMID:27514587

  15. Cosmetic Plastic Surgery Statistics

    MedlinePlus

    2014 Cosmetic Plastic Surgery Statistics Cosmetic Procedure Trends 2014 Plastic Surgery Statistics Report Please credit the AMERICAN SOCIETY OF PLASTIC SURGEONS when citing statistical data or using ...

  16. Plastics Technician.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 16 units to consider for use in a tech prep competency profile for the occupation of plastics technician. All the units listed will not necessarily apply to every situation or tech prep consortium, nor will all the competencies within each unit be appropriate. Several units appear within each specific occupation and would…

  17. Nonlinear plastic modes in disordered solids

    NASA Astrophysics Data System (ADS)

    Gartner, Luka; Lerner, Edan

    2016-01-01

    We propose a theoretical framework within which a robust micromechanical definition of precursors to plastic instabilities, often termed soft spots, naturally emerges. They are shown to be collective displacements (modes) z ̂ that correspond to local minima of a barrier function b (z ̂) , which depends solely on inherent structure information. We demonstrate how some heuristic searches for local minima of b (z ̂) can a priori detect the locus and geometry of imminent plastic instabilities with remarkable accuracy, at strains as large as γc-γ ˜10-2 away from the instability strain γc. Our findings suggest that the a priori detection of the entire field of soft spots can be effectively carried out by a systematic investigation of the landscape of b (z ̂) .

  18. Amorphous Silicon Display Backplanes on Plastic Substrates

    NASA Astrophysics Data System (ADS)

    Striakhilev, Denis; Nathan, Arokia; Vygranenko, Yuri; Servati, Peyman; Lee, Czang-Ho; Sazonov, Andrei

    2006-12-01

    Amorphous silicon (a-Si) thin-film transistor (TFT) backplanes are very promising for active-matrix organic light-emitting diode displays (AMOLEDs) on plastic. The technology benefits from a large manufacturing base, simple fabrication process, and low production cost. The concern lies in the instability of the TFTs threshold voltage (VT) and its low device mobility. Although VT-instability can be compensated by means of advanced multi-transistor pixel circuits, the lifetime of the display is still dependent on the TFT process quality and bias conditions. A-Si TFTs with field-effect mobility of 1.1 cm2/V · s and pixel driver circuits have been fabricated on plastic substrates at 150 °C. The circuits are characterized in terms of current drive capability and long-term stability of operation. The results demonstrate sufficient and stable current delivery and the ability of the backplane on plastic to meet AMOLED requirements.

  19. Photochromic plastics

    SciTech Connect

    Chu, N.Y.C.

    1990-12-31

    The benefits of photochromic glazing materials as well as other switchable devices for solar control and/or use have been analyzed. The analysis indicates that the saving in cooling costs may be significant for a commercial building. This saving can be further increased if other solar control technologies which operate in the solar spectra region outside the visible range are integrated with photochromic property. Photochromic plastics have the advantage of readiness to integrate with other solar control technologies as in the case of retrofit polyester film. The glazing applications of spirooxazines have only been considered recently. The few examples described in the preceding section are just exploratory. Improvements in photochromic performance and durability are definitely probable as more spirooxazine compounds and formulations are tested and stabilization methods are discovered. Recently, an all plastic model house was constructed by General Electric in which both photochromic and electrochromic switchable windows were employed. Thus, commercialization of photochromic plastics for glazing applications may not be as remote as it was not too long ago. 66 refs., 4 figs., 1 tab.

  20. Mechanical Instabilities of Biological Tubes

    NASA Astrophysics Data System (ADS)

    Hannezo, Edouard; Prost, Jacques; Joanny, Jean-François

    2012-07-01

    We study theoretically the morphologies of biological tubes affected by various pathologies. When epithelial cells grow, the negative tension produced by their division provokes a buckling instability. Several shapes are investigated: varicose, dilated, sinuous, or sausagelike. They are all found in pathologies of tracheal, renal tubes, or arteries. The final shape depends crucially on the mechanical parameters of the tissues: Young’s modulus, wall-to-lumen ratio, homeostatic pressure. We argue that since tissues must be in quasistatic mechanical equilibrium, abnormal shapes convey information as to what causes the pathology. We calculate a phase diagram of tubular instabilities which could be a helpful guide for investigating the underlying genetic regulation.

  1. Longitudinal instability in HIF beams

    SciTech Connect

    Smith, L.

    1991-04-01

    In contrast to an electron induction accelerator, in which the particle velocity is virtually constant, the resistive and inductive components of accelerating module impedances can cause instability for an intense non-relativistic heavy ion beam accelerated in a similar structure. Since focusing requirements at the fusion pellet imply a momentum spread {approx lt}3 {times} 10{sup {minus}4} at the end of the accelerator, it is essential to understand and suppress this instability. There is also an economic issue involved for this application; selection of parameters to control the instability must not unduly affect the efficiency and cost of the accelerator. This paper will present the results of analytic and computational work on module impedances, growth rates and feed back (forward) systems. 2 refs., 3 figs.

  2. Chondral Injury in Patellofemoral Instability

    PubMed Central

    Lustig, Sébastien; Servien, Elvire; Neyret, Philippe

    2014-01-01

    Objective: Patellofemoral instability is common and affects a predominantly young age group. Chondral injury occurs in up to 95%, and includes osteochondral fractures and loose bodies acutely and secondary degenerative changes in recurrent cases. Biomechanical abnormalities, such as trochlear dysplasia, patella alta, and increased tibial tuberosity-trochlear groove distance, predispose to both recurrent dislocations and patellofemoral arthrosis. Design: In this article, we review the mechanisms of chondral injury in patellofemoral instability, diagnostic modalities, the distribution of lesions seen in acute and episodic dislocation, and treatments for articular cartilage lesions of the patellofemoral joint. Results: Little specific evidence exists for cartilage treatments in patellofemoral instability. In general, the results of reparative and restorative procedures in the patellofemoral joint are inferior to those observed in other compartments of the knee. Conclusion: Given the increased severity of chondral lesions and progression to osteoarthritis seen with recurrent dislocations, careful consideration should be given to early stabilisation in patients with predisposing factors. PMID:26069693

  3. Cultural diversity, economic development and societal instability

    USGS Publications Warehouse

    Nettle, D.; Grace, J.B.; Choisy, M.; Cornell, H.V.; Guegan, J.-F.; Hochberg, M.E.

    2007-01-01

    Background. Social scientists have suggested that cultural diversity in a nation leads to societal instability. However, societal instability may be affected not only by within-nation on ?? diversity, but also diversity between a nation and its neighbours or ?? diversity. It is also necessary to distinguish different domains of diversity, namely linguistic, ethnic and religious, and to distinguish between the direct effects of diversity on societal instability, and effects that are mediated by economic conditions. Methodology/Principal Findings. We assembled a large cross-national dataset with information on ?? and ?? cultural diversity, economic conditions, and indices of societal instability. Structural equation modeling was used to evaluate the direct and indirect effects of cultural diversity on economics and societal stability. Results show that different type and domains of diversity have interacting effects. As previously documented, linguistic ?? diversity has a negative effect on economic performance, and we show that it is largely through this economic mechanism that it affects societal instability. For ?? diversity, the higher the linguistic diversity among nations in a region, the less stable the nation. But, religious ?? diversity has the opposite effect, reducing instability, particularly in the presence of high linguistic diversity. Conclusions. Within-nation linguistic diversity is associated with reduced economic performance, which, in turn, increases societal instability. Nations which differ linguistically from their neighbors are also less stable. However, religious diversity between, neighboring nations has the opposite effect, decreasing societal instability.

  4. Linear analysis of incompressible Rayleigh-Taylor instability in solids.

    PubMed

    Piriz, A R; Cela, J J López; Tahir, N A

    2009-10-01

    The study of the linear stage of the incompressible Rayleigh-Taylor instability in elastic-plastic solids is performed by considering thick plates under a constant acceleration that is also uniform except for a small sinusoidal ripple in the horizontal plane. The analysis is carried out by using an analytical model based on the Newton second law and it is complemented with extensive two-dimensional numerical simulations. The conditions for marginal stability that determine the instability threshold are derived. Besides, the boundary for the transition from the elastic to the plastic regime is obtained and it is demonstrated that such a transition is not a sufficient condition for instability. The model yields complete analytical solutions for the perturbation amplitude evolution and reveals the main physical process that governs the instability. The theory is in general agreement with the numerical simulations and provides useful quantitative results. Implications for high-energy-density-physics experiments are also discussed. PMID:19905434

  5. Plastic ingestion by Procellariiformes in Southern Brazil.

    PubMed

    Colabuono, Fernanda I; Barquete, Viviane; Domingues, Beatriz S; Montone, Rosalinda C

    2009-01-01

    The Procellariiformes are the birds most affected by plastic pollution. Plastic fragments and pellets were the most frequent items found in the digestive tract of eight species of Procellariiformes incidentally caught by longline fisheries as well as beached birds in Southern Brazil. Plastic objects were found in 62% of the petrels and 12% of the albatrosses. The Great shearwater, Manx shearwater, Cory's shearwater and Antarctic fulmar were found to have greater quantities and frequencies of occurrence of plastic. There was no significant difference in the number of plastics between the birds from longline fisheries and beached birds. No correlation was found between the number of prey and number of plastics in the digestive tract of the birds analyzed, but this does not discard the hypothesis that, in some cases, the presence of plastic in the digestive tract has a negative effect on the feeding efficiency of these birds. PMID:18840384

  6. TRANSVERSE INSTABILITIES IN RHIC.

    SciTech Connect

    Blaskiewicz, M; Cameron, P; Catalan-Lasheras, N; Dawson, C; Degen, C; Drees, K; Fischer, W; Koropsak, E; Michnoff, R; Montag, C; Roser, T

    2003-05-12

    The beam quality in RHIC can be significantly impacted by a transverse instability which can occur just after transition [1]. Data characterizing the instability are presented and analyzed. Techniques for ameliorating the situation are considered.

  7. Turbine instabilities: Case histories

    NASA Technical Reports Server (NTRS)

    Laws, C. W.

    1985-01-01

    Several possible causes of turbine rotor instability are discussed and the related design features of a wide range of turbomachinery types and sizes are considered. The instrumentation options available for detecting rotor instability and assessing its severity are also discussed.

  8. Neurocardiovascular Instability and Cognition

    PubMed Central

    O’Callaghan, Susan; Kenny, Rose Anne

    2016-01-01

    Neurocardiovascular instability (NCVI) refers to abnormal neural control of the cardiovascular system affecting blood pressure and heart rate behavior. Autonomic dysfunction and impaired cerebral autoregulation in aging contribute to this phenomenon characterized by hypotension and bradyarrhythmia. Ultimately, this increases the risk of falls and syncope in older people. NCVI is common in patients with neurodegenerative disorders including dementia. This review discusses the various syndromes that characterize NCVI icluding hypotension, carotid sinus hypersensitivity, postprandial hypotension and vasovagal syncope and how they may contribute to the aetiology of cognitive decline. Conversely, they may also be a consequence of a common neurodegenerative process. Regardless, recognition of their association is paramount in optimizing management of these patients. PMID:27505017

  9. Mix and Instability Growth from Oblique Shock

    NASA Astrophysics Data System (ADS)

    Molitoris, John D.; Batteux, Jan D.; Garza, Raul G.; Tringe, Joseph W.; Souers, P. Clark; Energetic Materials Center Team

    2011-06-01

    We have studied the formation and evolution of shock-induced turbulent mix resulting from pre-emplaced interface features in a cylindrical geometry. In this research a solid cylindrical core of high-explosive was detonated to create an oblique shock wave that is driven through a cylindrical interface. Pre-emplaced surface features in plastic and aluminum were studied. Time sequence radiographic imaging was utilized to observe the resulting instability formation from the growth phase to onset of mix and turbulence. Different types of pre-emplaced structures at the interface resulted in a range of mix and instability conditions, with some much more effective at creating a well-mixed region. The plastic used here was porous polyethylene. Interfaces studied were between the high-explosive/aluminum, aluminum/plastic, and finally plastic/air. Radiographic image data will be compared with numerical simulations of the experiments. Partial support for this research was obtained from the Advanced Energetics Program, Defense Threat Reduction Agency. This work performed under the auspices of the U. S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  10. MIX and Instability Growth from Oblique Shock

    SciTech Connect

    Molitoris, J D; Batteux, J D; Garza, R G; Tringe, J W; Souers, P C; Forbes, J W

    2011-07-22

    We have studied the formation and evolution of shock-induced mix resulting from interface features in a divergent cylindrical geometry. In this research a cylindrical core of high-explosive was detonated to create an oblique shock wave and accelerate the interface. The interfaces studied were between the high-explosive/aluminum, aluminum/plastic, and finally plastic/air. Pre-emplaced surface features added to the aluminum were used to modify this interface. Time sequence radiographic imaging quantified the resulting instability formation from the growth phase to over 60 {micro}s post-detonation. Thus allowing the study of the onset of mix and evolution to turbulence. The plastic used here was porous polyethylene. Radiographic image data are compared with numerical simulations of the experiments.

  11. The Future of Plastic Surgery: Surgeon's Perspective.

    PubMed

    Ozturk, Sinan; Karagoz, Huseyin; Zor, Fatih

    2015-11-01

    Since the days of Sushruta, innovation has shaped the history of plastic surgery. Plastic surgeons have always been known as innovators or close followers of innovations. With this descriptive international survey study, the authors aimed to evaluate the future of plastic surgeons by analyzing how plastic surgery and plastic surgeons will be affected by new trends in medicine. Aesthetic surgery is the main subclass of plastic surgery thought to be the one that will change the most in the future. Stem cell therapy is considered by plastic surgeons to be the most likely "game changer." Along with changes in surgery, plastic surgeons also expect changes in plastic surgery education. The most approved assumption for the future of plastic surgery is, "The number of cosmetic nonsurgical procedures will increase in the future." If surgeons want to have better outcomes in their practice, they must at least be open minded for innovations if they do not become innovators themselves. Besides the individual effort of each surgeon, international and local plastic surgery associations should develop new strategies to adopt these innovations in surgical practice and education. PMID:26594981

  12. Understanding Multidirectional Instability of the Shoulder

    PubMed Central

    Cordasco, Frank A.

    2000-01-01

    Objective: To provide an overview of the evaluation and treatment of the patient with multidirectional shoulder instability. Data Sources: I searched MEDLINE for the years from 1980 to 2000 using the key words “shoulder joint,” “instability,” “dislocation,” “multidirectional shoulder instability,” and “inferior capsular shift.” Data Synthesis: Multidirectional instability is symptomatic glenohumeral subluxation or dislocation in more than 1 direction: anterior, inferior, or posterior. The primary pathology is a loose and patulous capsule, and the entity is more common than previously recognized. Multidirectional instability affects young, sedentary patients with generalized ligamentous laxity, often with bilateral symptoms and an atraumatic history, but it also affects athletes, many of whom have sustained injuries. Patients with multidirectional instability may also have Bankart lesions and humeral head impression defects. Conclusions/Recommendations: Patients with multidirectional instability must be identified before appropriate treatment can be initiated. If a course of rehabilitation fails to improve the patient's symptoms, an inferior capsular shift procedure has been demonstrated to be an effective surgical option. ImagesFigure 1.Figure 2.Figure 3.Figure 4.Figure 5.Figure 6.Figure 7.Figure 8.Figure 9.Figure 10. PMID:16558641

  13. Radiative heat transport instability in a laser produced inhomogeneous plasma

    SciTech Connect

    Bychenkov, V. Yu.; Rozmus, W.

    2015-08-15

    A laser produced high-Z plasma in which an energy balance is achieved due to radiation emission and radiative heat transfer supports ion acoustic instability. A linear dispersion relation is derived, and instability is compared to the radiation cooling instability [R. G. Evans, Plasma Phys. Controlled Fusion 27, 751 (1985)]. Under conditions of indirect drive fusion experiments, the driving term for the instability is the radiative heat flux and, in particular, the density dependence of the radiative heat conductivity. A specific example of thermal Bremsstrahlung radiation source has been considered. This instability may lead to plasma jet formation and anisotropic x-ray generation, thus affecting inertial confinement fusion related experiments.

  14. Scribable coating for plastic films

    NASA Technical Reports Server (NTRS)

    Clark, R. T.

    1967-01-01

    Scribable opaque coating for transparent plastic film tape is not affected by aging, vacuum, and moderate temperature extremes. It consists of titanium dioxide, a water-compatible acrylic polymer emulsion, and a detergent. The coating mixture is readily dispersed in water before it is dried.

  15. Visco-plastic sculpting

    NASA Astrophysics Data System (ADS)

    Hormozi, S.; Dunbrack, G.; Frigaard, I. A.

    2014-09-01

    Visco-plastic lubrication (VPL) has been established as a method for reliably suppressing interfacial instabilities and enhancing flow stability for multi-layer systems. Here we extend this methodology to the formation of shaped interfaces in multifluid core-annular configurations. We study multi-layer VPL flows in which we perform both experiment and computation with oscillating the flow rates of the individual phases. According to the flow rate variations we succeed in freezing in a range of different interfacial patterns. Experiments performed with carbopol as lubricating fluid, and with xanthan and polyethylene oxide solutions as core fluid, serve to illustrate the potential of the method. We show that single pulsed changes in the imposed inflow rates can result in small interface indentations that remain frozen into the interface as it propagates downstream. Repeated pulses produce periodically patterned interfaces. We are able to control the frequency and amplitude of the interfacial patterns, but not directly the shape. Inelastic core fluids have been observed to produce rounded bulges whereas elastic core fluids have produced diamond shapes. Moreover, numerical simulations extend the range of shapes achievable and give us interesting insights into the forming process.

  16. Evolution of environmental cues for phenotypic plasticity.

    PubMed

    Chevin, Luis-Miguel; Lande, Russell

    2015-10-01

    Phenotypically plastic characters may respond to multiple variables in their environment, but the evolutionary consequences of this phenomenon have rarely been addressed theoretically. We model the evolution of linear reaction norms in response to several correlated environmental variables, in a population undergoing stationary environmental fluctuations. At evolutionary equilibrium, the linear combination of environmental variables that acts as a developmental cue for the plastic trait is the multivariate best linear predictor of changes in the optimum. However, the reaction norm with respect to any single environmental variable may exhibit nonintuitive patterns. Apparently maladaptive, or hyperadaptive plasticity can evolve with respect to single environmental variables, and costs of plasticity may increase, rather than reduce, plasticity in response to some variables. We also find conditions for the evolution of an indirect environmental indicator that affects expression of a plastic phenotype, despite not influencing natural selection on it. PMID:26292649

  17. Joint instability and osteoarthritis.

    PubMed

    Blalock, Darryl; Miller, Andrew; Tilley, Michael; Wang, Jinxi

    2015-01-01

    Joint instability creates a clinical and economic burden in the health care system. Injuries and disorders that directly damage the joint structure or lead to joint instability are highly associated with osteoarthritis (OA). Thus, understanding the physiology of joint stability and the mechanisms of joint instability-induced OA is of clinical significance. The first section of this review discusses the structure and function of major joint tissues, including periarticular muscles, which play a significant role in joint stability. Because the knee, ankle, and shoulder joints demonstrate a high incidence of ligament injury and joint instability, the second section summarizes the mechanisms of ligament injury-associated joint instability of these joints. The final section highlights the recent advances in the understanding of the mechanical and biological mechanisms of joint instability-induced OA. These advances may lead to new opportunities for clinical intervention in the prevention and early treatment of OA. PMID:25741184

  18. Joint Instability and Osteoarthritis

    PubMed Central

    Blalock, Darryl; Miller, Andrew; Tilley, Michael; Wang, Jinxi

    2015-01-01

    Joint instability creates a clinical and economic burden in the health care system. Injuries and disorders that directly damage the joint structure or lead to joint instability are highly associated with osteoarthritis (OA). Thus, understanding the physiology of joint stability and the mechanisms of joint instability-induced OA is of clinical significance. The first section of this review discusses the structure and function of major joint tissues, including periarticular muscles, which play a significant role in joint stability. Because the knee, ankle, and shoulder joints demonstrate a high incidence of ligament injury and joint instability, the second section summarizes the mechanisms of ligament injury-associated joint instability of these joints. The final section highlights the recent advances in the understanding of the mechanical and biological mechanisms of joint instability-induced OA. These advances may lead to new opportunities for clinical intervention in the prevention and early treatment of OA. PMID:25741184

  19. Instability in Rotating Machinery

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The proceedings contain 45 papers on a wide range of subjects including flow generated instabilities in fluid flow machines, cracked shaft detection, case histories of instability phenomena in compressors, turbines, and pumps, vibration control in turbomachinery (including antiswirl techniques), and the simulation and estimation of destabilizing forces in rotating machines. The symposium was held to serve as an update on the understanding and control of rotating machinery instability problems.

  20. Laboratory blast wave driven instabilities

    NASA Astrophysics Data System (ADS)

    Kuranz, Carolyn

    2008-04-01

    This presentation discusses experiments well-scaled to the blast wave driven instabilities during the explosion phase of SN1987A. Blast waves occur following a sudden, finite release of energy, and consist of a shock front followed by a rarefaction wave. When a blast wave crosses an interface with a decrease in density, hydrodynamic instabilities will develop. These experiments include target materials scaled in density to the He/H layer in SN1987A. About 5 kJ of laser energy from the Omega Laser facility irradiates a 150 μm plastic layer that is followed by a low density foam layer. A blast wave structure similar to those in supernovae, is created in the plastic layer. The blast wave crosses a perturbed interface, which produces nonlinear, unstable growth dominated by the Rayleigh-Taylor (RT) instability. Recent experiments have been performed using complex initial conditions featuring a three-dimensional interface structure with a wavelength of 71 μm in two orthogonal directions, at times supplemented by an additional sinusoidal mode of 212 μm or 424 μm. We have detected the interface structure under these conditions, using dual orthogonal radiographs on some shots, and will show some of the resulting data. Recent advancements in our x-ray backlighting techniques have greatly improved the resolution of our x-ray radiographic images. Under certain conditions, the improved images show some mass extending beyond the RT spike and penetrating further than previously observed. Current simulations do not show this phenomenon. This presentation will discuss the amount of mass in these spike extensions as well as the error analysis of this calculation. Future experiments will also be discussed. They will be focusing on realistic initial conditions based on 3D stellar evolution models. This research was sponsored by the Stewardship Science Academic Alliances Program through DOE Research Grants DE-FG52-07NA28058, DE-FG52-04NA00064, and other grants and contracts.

  1. Nonlocal magnetorotational instability

    SciTech Connect

    Mikhailovskii, A. B.; Erokhin, N. N.; Lominadze, J. G.; Galvao, R. M. O.; Churikov, A. P.; Kharshiladze, O. A.; Amador, C. H. S.

    2008-05-15

    An analytical theory of the nonlocal magnetorotational instability (MRI) is developed for the simplest astrophysical plasma model. It is assumed that the rotation frequency profile has a steplike character, so that there are two regions in which it has constant different values, separated by a narrow transition layer. The surface wave approach is employed to investigate the MRI in this configuration. It is shown that the main regularities of the nonlocal MRI are similar to those of the local instability and that driving the nonaxisymmetric MRI is less effective than the axisymmetric one, also for the case of the nonlocal instability. The existence of nonlocal instabilities in nonmagnetized plasma is predicted.

  2. Influence of ion streaming instabilities on transport near plasma boundaries

    NASA Astrophysics Data System (ADS)

    Baalrud, Scott D.

    2016-04-01

    Plasma boundary layers are susceptible to electrostatic instabilities driven by ion flows in presheaths and, when present, these instabilities can influence transport. In plasmas with a single species of positive ion, ion-acoustic instabilities are expected under conditions of low pressure and large electron-to-ion temperature ratio ({{T}e}/{{T}i}\\gg 1 ). In plasmas with two species of positive ions, ion-ion two-stream instabilities can also be excited. The stability phase-space is characterized using the Penrose criterion and approximate linear dispersion relations. Predictions for how these instabilities affect ion and electron transport in presheaths, including rapid thermalization due to instability-enhanced collisions and an instability-enhanced ion-ion friction force, are briefly reviewed. Recent experimental tests of these predictions are discussed along with research needs required for further validation. The calculated stability boundaries provide a guide to determine the experimental conditions at which these effects can be expected.

  3. Oxytocin and Maternal Brain Plasticity.

    PubMed

    Kim, Sohye; Strathearn, Lane

    2016-09-01

    Although dramatic postnatal changes in maternal behavior have long been noted, we are only now beginning to understand the neurobiological mechanisms that support this transition. The present paper synthesizes growing insights from both animal and human research to provide an overview of the plasticity of the mother's brain, with a particular emphasis on the oxytocin system. We examine plasticity observed within the oxytocin system and discuss how these changes mediate an array of other adaptations observed within the maternal brain. We outline factors that affect the oxytocin-mediated plasticity of the maternal brain and review evidence linking disruptions in oxytocin functions to challenges in maternal adaptation. We conclude by suggesting a strategy for intervention with mothers who may be at risk for maladjustment during this transition to motherhood, while highlighting areas where further research is needed. PMID:27589498

  4. Model of plasticity of amorphous materials

    NASA Astrophysics Data System (ADS)

    Marchenko, V. I.; Misbah, Chaouqi

    2011-08-01

    Starting from a classical Kröener-Rieder kinematic picture for plasticity, we derive a set of dynamical equations describing plastic flow in a Lagrangian formulation. Our derivation is a natural and straightforward extension of simple fluids, elastic, and viscous solids theories. These equations contain the Maxwell model as a special limit. This paper is inspired by the particularly important work of Langer and coworkers. We shall show that our equations bear some resemblance with the shear-transformation zones model developed by Langer and coworkers. We shall point out some important differences. We discuss some results of plasticity, which can be described by the present model. We exploit the model equations for the simple examples: straining of a slab and a rod. We find that necking manifests always itself (not as a result of instability), except if the very special constant-velocity stretching process is imposed.

  5. Experimental observations of turbulent mixing due to Kelvin-Helmholtz instability on the OMEGA Laser Facility

    NASA Astrophysics Data System (ADS)

    Smalyuk, V. A.; Hansen, J. F.; Hurricane, O. A.; Langstaff, G.; Martinez, D.; Park, H.-S.; Raman, K.; Remington, B. A.; Robey, H. F.; Schilling, O.; Wallace, R.; Elbaz, Y.; Shimony, A.; Shvarts, D.; Di Stefano, C.; Drake, R. P.; Marion, D.; Krauland, C. M.; Kuranz, C. C.

    2012-09-01

    Shear-flow, Kelvin-Helmholtz (KH) turbulent mixing experiments were performed on the OMEGA Laser Facility [Boehly et al., Opt. Commun. 133, 495 (1997)] in which laser-driven shock waves propagated through a low-density plastic foam placed on top of a higher-density plastic foil. The plastic foil was comprised a thin iodine-doped plastic tracer layer bonded on each side to an undoped density-matched polyamide-imide plastic. Behind the shock front, lower-density foam plasma flowed over the higher-density plastic plasma, such that the interface between the foam and plastic was KH unstable. The initial perturbations consisted of pre-imposed, sinusoidal 2D perturbations, and broadband 3D perturbations due to surface roughness at the interface between the plastic and foam. KH instability growth was measured using side-on radiography with a point-projection 5-keV vanadium backlighter. Time-integrated images were captured on D-8 x-ray film. Spatial density profiles of iodine-doped plastic mixed with foam were inferred using x-ray radiographs. The mixing layer ensuing from the KH instability with layer width up to ˜100 μm was observed at a location ˜1 mm behind the shock front. The measured mixing layer width was in good agreement with predictions based on a simple self-similar model of KH instability growth using an estimate of the shear velocity obtained from numerical simulations of the experiments.

  6. Experimental observations of turbulent mixing due to Kelvin-Helmholtz instability on the OMEGA Laser Facility

    SciTech Connect

    Smalyuk, V. A.; Hansen, J. F.; Hurricane, O. A.; Langstaff, G.; Martinez, D.; Park, H.-S.; Raman, K.; Remington, B. A.; Robey, H. F.; Schilling, O.; Wallace, R.; Elbaz, Y.; Shimony, A.; Shvarts, D.; Di Stefano, C.; Drake, R. P.; Marion, D.; Krauland, C. M.; Kuranz, C. C.

    2012-09-15

    Shear-flow, Kelvin-Helmholtz (KH) turbulent mixing experiments were performed on the OMEGA Laser Facility [Boehly et al., Opt. Commun. 133, 495 (1997)] in which laser-driven shock waves propagated through a low-density plastic foam placed on top of a higher-density plastic foil. The plastic foil was comprised a thin iodine-doped plastic tracer layer bonded on each side to an undoped density-matched polyamide-imide plastic. Behind the shock front, lower-density foam plasma flowed over the higher-density plastic plasma, such that the interface between the foam and plastic was KH unstable. The initial perturbations consisted of pre-imposed, sinusoidal 2D perturbations, and broadband 3D perturbations due to surface roughness at the interface between the plastic and foam. KH instability growth was measured using side-on radiography with a point-projection 5-keV vanadium backlighter. Time-integrated images were captured on D-8 x-ray film. Spatial density profiles of iodine-doped plastic mixed with foam were inferred using x-ray radiographs. The mixing layer ensuing from the KH instability with layer width up to {approx}100 {mu}m was observed at a location {approx}1 mm behind the shock front. The measured mixing layer width was in good agreement with predictions based on a simple self-similar model of KH instability growth using an estimate of the shear velocity obtained from numerical simulations of the experiments.

  7. Plastic flow of polycrystalline materials

    NASA Astrophysics Data System (ADS)

    Langer, James

    Leo Kadanoff had a long interest in fluid flows, especially fingering instabilities. This interest was one example of his insatiable curiosity about simple, fundamentally important, and often multidisciplinary phenomena. Here is an example of another class of such phenomena that I had hoped to show him this year. The experts in polycrystalline solid mechanics have insisted for decades that their central problem - dislocation-mediated strain hardening - is intrinsically unsolvable. I think they're wrong. My colleagues and I have made progress recently in theories of both amorphous and polycrystalline plasticity by introducing an effective disorder temperature as a dynamical variable in our equations of motion. In this way, we have been able to describe how the densities of flow defects or dislocations evolve in response to external forcing, and thus to develop theories that promise to become as predictive, and full of surprises, as the laws of fluid flow. For Kadanoff session.

  8. Convective Instabilities in Liquid Foams

    NASA Technical Reports Server (NTRS)

    Veretennikov, Igor; Glazier, James A.

    2004-01-01

    The main goal of this work is to better understand foam behavior both on the Earth and in microgravity conditions and to determine the relation between a foam's structure and wetness and its rheological properties. Our experiments focused on the effects of the bubble size distribution (BSD) on the foam behavior under gradual or stepwise in the liquid flow rate and on the onset of the convective instability. We were able to show experimentally, that the BSD affects foam rheology very strongly so any theory must take foam texture into account.

  9. Ear Plastic Surgery

    MedlinePlus

    ... Meeting Calendar Find an ENT Doctor Near You Ear Plastic Surgery Ear Plastic Surgery Patient Health Information ... they may improve appearance and self-confidence. Can Ear Deformities Be Corrected? Formation of the ear during ...

  10. Plastic Surgery for Teenagers

    MedlinePlus

    ... or severe acne and scarring. Teens frequently gain self-esteem and confidence when their physical problems are corrected. ... art as a helpful index of anxiety and self-esteem with plastic surgery. Plastic and Reconstructive Surgery 2002. ...

  11. Plastic encapsulated parts

    SciTech Connect

    Castillo, T.

    1994-10-01

    Plastic semiconductor packages were characterized as possible alternatives for canned devices, which are susceptible to internal shorts caused by conductive particles. Highly accelerated stress testing (HAST) as well as electrical and mechanical testing were conducted on plastic technology devices.

  12. Periodontal Plastic Surgery

    MedlinePlus

    ... Dental Implants Dentures Direct Bonding Implants versus Bridges Orthodontics and Aligners Periodontal Plastic Surgery Porcelain Crowns Porcelain ... Dental Implants Dentures Direct Bonding Implants versus Bridges Orthodontics and Aligners Periodontal Plastic Surgery Porcelain Crowns Porcelain ...

  13. Plasticity and Geotechnics

    NASA Astrophysics Data System (ADS)

    Yu, Hai-Sui

    Plasticity and Geotechnics is the first attempt to summarize and present, in one volume, the major developments achieved to date in the field of plasticity theory for geotechnical materials and its applications to geotechnical analysis and design.

  14. Growth instabilities in mechanical breakdown under mechanical and thermal stresses

    NASA Astrophysics Data System (ADS)

    Zhang, S.-Z.; Louis, E.; Plá, O.; Guinea, F.

    1995-12-01

    A linear stability analysis is used to investigate crack growth in two dimensional elastic media, and under mechanical or thermal stresses. Although in most cases a circular geometry is considered, the instability of a planar crack is also discussed. Several boundary conditions and size effects are considered. The results indicate that the tendency towards instabilities in mechanical breakdown is stronger than in the case of growth in fields governed by the Laplace equation (diffusion or electrostatic fields), in line with the smaller fractal dimensions obtained in the first case. Instabilities under thermal stresses are shown to depend on the actual thermal gradients. Finally, a model previously investigated numerically is used to show that plasticity decreases the strength of the instability. (c) 1995 The American Physical Society

  15. Circuit reactivation dynamically regulates synaptic plasticity in neocortex

    NASA Astrophysics Data System (ADS)

    Kruskal, Peter B.; Li, Lucy; Maclean, Jason N.

    2013-10-01

    Circuit reactivations involve a stereotyped sequence of neuronal firing and have been behaviourally linked to memory consolidation. Here we use multiphoton imaging and patch-clamp recording, and observe sparse and stereotyped circuit reactivations that correspond to UP states within active neurons. To evaluate the effect of the circuit on synaptic plasticity, we trigger a single spike-timing-dependent plasticity (STDP) pairing once per circuit reactivation. The pairings reliably fall within a particular epoch of the circuit sequence and result in long-term potentiation. During reactivation, the amplitude of plasticity significantly correlates with the preceding 20-25 ms of membrane depolarization rather than the depolarization at the time of pairing. This circuit-dependent plasticity provides a natural constraint on synaptic potentiation, regulating the inherent instability of STDP in an assembly phase-sequence model. Subthreshold voltage during endogenous circuit reactivations provides a critical informative context for plasticity and facilitates the stable consolidation of a spatiotemporal sequence.

  16. Processing of plastics

    PubMed Central

    Spaak, Albert

    1975-01-01

    An overview is given of the processing of plastic materials from the handling of polymers in the pellet and powder form to manufacturing of a plastic fabricated product. Various types of equipment used and melt processing ranges of various polymer formulations to make the myriad of plastic products that are commercially available are discussed. PMID:1175556

  17. Plastics in Building.

    ERIC Educational Resources Information Center

    Skeist, Irving, Ed.

    The evaluation and use of plastics in the construction industry are explained. The contributors offer extensive, timely, and thoroughly researched data on the chemistry, properties, functions, engineering behavior, and specific applications of plastics to building requirements. The major subjects discussed in depth are--(1) the role of plastics in…

  18. Tomorrow's Plastic World

    ERIC Educational Resources Information Center

    Macdonald, Averil

    2005-01-01

    Far from being just cheap packaging materials, plastics may be the materials of tomorrow. Plastic can conduct electricity, and this opens up a host of high-tech possibilities in the home and in energy generation. These possibilities are discussed here along with how plastic can be recycled and perhaps even grown.

  19. Plasticity of Nonneuronal Brain Tissue: Roles in Developmental Disorders

    ERIC Educational Resources Information Center

    Dong, Willie K.; Greenough, William T.

    2004-01-01

    Neuronal and nonneuronal plasticity are both affected by environmental and experiential factors. Remodeling of existing neurons induced by such factors has been observed throughout the brain, and includes alterations in dendritic field dimensions, synaptogenesis, and synaptic morphology. The brain loci affected by these plastic neuronal changes…

  20. Plastic Accumulation in the Mediterranean Sea

    PubMed Central

    Cózar, Andrés; Sanz-Martín, Marina; Martí, Elisa; González-Gordillo, J. Ignacio; Ubeda, Bárbara; Gálvez, José Á.; Irigoien, Xabier; Duarte, Carlos M.

    2015-01-01

    Concentrations of floating plastic were measured throughout the Mediterranean Sea to assess whether this basin can be regarded as a great accumulation region of plastic debris. We found that the average density of plastic (1 item per 4 m2), as well as its frequency of occurrence (100% of the sites sampled), are comparable to the accumulation zones described for the five subtropical ocean gyres. Plastic debris in the Mediterranean surface waters was dominated by millimeter-sized fragments, but showed a higher proportion of large plastic objects than that present in oceanic gyres, reflecting the closer connection with pollution sources. The accumulation of floating plastic in the Mediterranean Sea (between 1,000 and 3,000 tons) is likely related to the high human pressure together with the hydrodynamics of this semi-enclosed basin, with outflow mainly occurring through a deep water layer. Given the biological richness and concentration of economic activities in the Mediterranean Sea, the affects of plastic pollution on marine and human life are expected to be particularly frequent in this plastic accumulation region. PMID:25831129

  1. Plastic accumulation in the Mediterranean sea.

    PubMed

    Cózar, Andrés; Sanz-Martín, Marina; Martí, Elisa; González-Gordillo, J Ignacio; Ubeda, Bárbara; Gálvez, José Á; Irigoien, Xabier; Duarte, Carlos M

    2015-01-01

    Concentrations of floating plastic were measured throughout the Mediterranean Sea to assess whether this basin can be regarded as a great accumulation region of plastic debris. We found that the average density of plastic (1 item per 4 m2), as well as its frequency of occurrence (100% of the sites sampled), are comparable to the accumulation zones described for the five subtropical ocean gyres. Plastic debris in the Mediterranean surface waters was dominated by millimeter-sized fragments, but showed a higher proportion of large plastic objects than that present in oceanic gyres, reflecting the closer connection with pollution sources. The accumulation of floating plastic in the Mediterranean Sea (between 1,000 and 3,000 tons) is likely related to the high human pressure together with the hydrodynamics of this semi-enclosed basin, with outflow mainly occurring through a deep water layer. Given the biological richness and concentration of economic activities in the Mediterranean Sea, the affects of plastic pollution on marine and human life are expected to be particularly frequent in this plastic accumulation region. PMID:25831129

  2. Chiral plasma instabilities.

    PubMed

    Akamatsu, Yukinao; Yamamoto, Naoki

    2013-08-01

    We study the collective modes in relativistic electromagnetic or quark-gluon plasmas with an asymmetry between left- and right-handed chiral fermions, based on the recently formulated kinetic theory with Berry curvature corrections. We find that there exists an unstable mode, signaling the presence of a plasma instability. We argue the fate of this "chiral plasma instability" including the effect of collisions, and briefly discuss its relevance in heavy ion collisions and compact stars. PMID:23952387

  3. Equilibrium Electroconvective Instability

    NASA Astrophysics Data System (ADS)

    Rubinstein, I.; Zaltzman, B.

    2015-03-01

    Since its prediction 15 years ago, hydrodynamic instability in concentration polarization at a charge-selective interface has been attributed to nonequilibrium electro-osmosis related to the extended space charge which develops at the limiting current. This attribution had a double basis. On the one hand, it has been recognized that neither equilibrium electro-osmosis nor bulk electroconvection can yield instability for a perfectly charge-selective solid. On the other hand, it has been shown that nonequilibrium electro-osmosis can. The first theoretical studies in which electro-osmotic instability was predicted and analyzed employed the assumption of perfect charge selectivity for the sake of simplicity and so did the subsequent studies of various time-dependent and nonlinear features of electro-osmotic instability. In this Letter, we show that relaxing the assumption of perfect charge selectivity (tantamount to fixing the electrochemical potential of counterions in the solid) allows for the equilibrium electroconvective instability. In addition, we suggest a simple experimental test for determining the true, either equilibrium or nonequilibrium, origin of instability in concentration polarization.

  4. Affective Dynamics in Psychopathology

    PubMed Central

    Trull, Timothy J.; Lane, Sean P.; Koval, Peter; Ebner-Priemer, Ulrich W.

    2016-01-01

    We discuss three varieties of affective dynamics (affective instability, emotional inertia, and emotional differentiation). In each case, we suggest how these affective dynamics should be operationalized and measured in daily life using time-intensive methods, like ecological momentary assessment or ambulatory assessment, and recommend time-sensitive analyses that take into account not only the variability but also the temporal dependency of reports. Studies that explore how these affective dynamics are associated with psychological disorders and symptoms are reviewed, and we emphasize that these affective processes are within a nexus of other components of emotion regulation.

  5. Filamentation Instability of Counterstreaming Laser-Driven Plasmas

    NASA Astrophysics Data System (ADS)

    Fox, W.; Fiksel, G.; Bhattacharjee, A.; Chang, P.-Y.; Germaschewski, K.; Hu, S. X.; Nilson, P. M.

    2013-11-01

    Filamentation due to the growth of a Weibel-type instability was observed in the interaction of a pair of counterstreaming, ablatively driven plasma flows, in a supersonic, collisionless regime relevant to astrophysical collisionless shocks. The flows were created by irradiating a pair of opposing plastic (CH) foils with 1.8 kJ, 2-ns laser pulses on the OMEGA EP Laser System. Ultrafast laser-driven proton radiography was used to image the Weibel-generated electromagnetic fields. The experimental observations are in good agreement with the analytical theory of the Weibel instability and with particle-in-cell simulations.

  6. Magneto-Rayleigh-Taylor instability in solid media

    NASA Astrophysics Data System (ADS)

    Sun, Y. B.; Piriz, A. R.

    2014-07-01

    A linear analysis of the magneto-Rayleigh-Taylor instability at the interface between a Newtonian fluid and an elastic-plastic solid is performed by considering a uniform magnetic B →, parallel to the interface, which has diffused into the fluid but not into the solid. It is found that the magnetic field attributes elastic properties to the viscous fluid which enhance the stability region by stabilizing all the perturbation wavelengths shorter than λ 0 ∝ B 2 for any initial perturbation amplitude. Longer wavelengths are stabilized by the mechanical properties of the solid provided that the initial perturbation wavelength is smaller than a threshold value determined by the yield strength and the shear modulus of the solid. Beyond this threshold, the amplitude grows initially with a growth rate reduced by the solid strength properties. However, such properties do not affect the asymptotic growth rate which is only determined by the magnetic field and the fluid viscosity. The described physical situation intends to resemble some of the features present in recent experiments involving the magnetic shockless acceleration of flyers plates.

  7. Magneto-Rayleigh-Taylor instability in solid media

    SciTech Connect

    Sun, Y. B.; Piriz, A. R.

    2014-07-15

    A linear analysis of the magneto-Rayleigh-Taylor instability at the interface between a Newtonian fluid and an elastic-plastic solid is performed by considering a uniform magnetic B{sup →}, parallel to the interface, which has diffused into the fluid but not into the solid. It is found that the magnetic field attributes elastic properties to the viscous fluid which enhance the stability region by stabilizing all the perturbation wavelengths shorter than λ{sub 0}∝B{sup 2} for any initial perturbation amplitude. Longer wavelengths are stabilized by the mechanical properties of the solid provided that the initial perturbation wavelength is smaller than a threshold value determined by the yield strength and the shear modulus of the solid. Beyond this threshold, the amplitude grows initially with a growth rate reduced by the solid strength properties. However, such properties do not affect the asymptotic growth rate which is only determined by the magnetic field and the fluid viscosity. The described physical situation intends to resemble some of the features present in recent experiments involving the magnetic shockless acceleration of flyers plates.

  8. Our plastic age.

    PubMed

    Thompson, Richard C; Swan, Shanna H; Moore, Charles J; vom Saal, Frederick S

    2009-07-27

    Within the last few decades, plastics have revolutionized our daily lives. Globally we use in excess of 260 million tonnes of plastic per annum, accounting for approximately 8 per cent of world oil production. In this Theme Issue of Philosophical Transactions of the Royal Society, we describe current and future trends in usage, together with the many benefits that plastics bring to society. At the same time, we examine the environmental consequences resulting from the accumulation of waste plastic, the effects of plastic debris on wildlife and concerns for human health that arise from the production, usage and disposal of plastics. Finally, we consider some possible solutions to these problems together with the research and policy priorities necessary for their implementation. PMID:19528049

  9. Our plastic age

    PubMed Central

    Thompson, Richard C.; Swan, Shanna H.; Moore, Charles J.; vom Saal, Frederick S.

    2009-01-01

    Within the last few decades, plastics have revolutionized our daily lives. Globally we use in excess of 260 million tonnes of plastic per annum, accounting for approximately 8 per cent of world oil production. In this Theme Issue of Philosophical Transactions of the Royal Society, we describe current and future trends in usage, together with the many benefits that plastics bring to society. At the same time, we examine the environmental consequences resulting from the accumulation of waste plastic, the effects of plastic debris on wildlife and concerns for human health that arise from the production, usage and disposal of plastics. Finally, we consider some possible solutions to these problems together with the research and policy priorities necessary for their implementation. PMID:19528049

  10. Plasticized phenolphthalein polycarbonate

    NASA Technical Reports Server (NTRS)

    Harrison, E. S.

    1976-01-01

    Phenolphthalein polycarbonate was successfully plasticized with polychlorinated biphenyls (e.g., Aroclor 1231) or tricresyl phosphate and cast from tetrahydrofuran to give clear films without loss of fire resistance. At loadings of 20 to 30 percent plasticizer the Tg was lowered to approximately 100 C which would render phenolphthalein polycarbonate easily moldable. Although these materials had some mechanical integrity as shown by their film forming ability, the room temperature toughness of the plasticized polymer was not significantly improved over unmodified polymer.

  11. Buckling instability in arteries.

    PubMed

    Vandiver, Rebecca M

    2015-04-21

    Arteries can become tortuous in response to abnormal growth stimuli, genetic defects and aging. It is suggested that a buckling instability is a mechanism that might lead to artery tortuosity. Here, the buckling instability in arteries is studied by examining asymmetric modes of bifurcation of two-layer cylindrical structures that are residually stressed. These structures are loaded by an axial force, internal pressure and have nonlinear, anisotropic, hyperelastic responses to stresses. Strain-softening and reduced opening angle are shown to lower the critical internal pressure leading to buckling. In addition, the ratio of the media thickness to the adventitia thickness is shown to have a dramatic impact on arterial instability. PMID:25661070

  12. Electrokinetic instability in microchannels

    NASA Astrophysics Data System (ADS)

    Schiffbauer, Jarrod; Demekhin, Evgeny A.; Ganchenko, Georgy

    2012-05-01

    The effect of geometric confinement on electroconvective instability due to nonequilibrium electro-osmotic slip at the interface of an electrolytic fluid and charge-selective solid is studied. It is shown that the topology of the marginal stability curves and the behavior of the critical parameters depend strongly on both channel geometry and dimensionless Debye length at low voltages for sufficiently deep channels, corresponding to the Rubinstein-Zaltzman instability mechanism, but that stability is governed almost entirely by channel depth for narrow channels at higher voltages. For shallow channels, it is shown that above a transition threshold, determined by both channel depth and Debye length, the low-voltage instability is completely suppressed.

  13. Additives in plastics.

    PubMed Central

    Deanin, R D

    1975-01-01

    The polymers used in plastics are generally harmless. However, they are rarely used in pure form. In almost all commercial plastics, they are "compounded" with monomeric ingredients to improve their processing and end-use performance. In order of total volume used, these monomeric additives may be classified as follows: reinforcing fibers, fillers, and coupling agents; plasticizers; colorants; stabilizers (halogen stabilizers, antioxidants, ultraviolet absorbers, and biological preservatives); processing aids (lubricants, others, and flow controls); flame retardants, peroxides; and antistats. Some information is already available, and much more is needed, on potential toxicity and safe handling of these additives during processing and manufacture of plastics products. PMID:1175566

  14. Plastics and health risks.

    PubMed

    Halden, Rolf U

    2010-01-01

    By 2010, the worldwide annual production of plastics will surpass 300 million tons. Plastics are indispensable materials in modern society, and many products manufactured from plastics are a boon to public health (e.g., disposable syringes, intravenous bags). However, plastics also pose health risks. Of principal concern are endocrine-disrupting properties, as triggered for example by bisphenol A and di-(2-ethylhexyl) phthalate (DEHP). Opinions on the safety of plastics vary widely, and despite more than five decades of research, scientific consensus on product safety is still elusive. This literature review summarizes information from more than 120 peer-reviewed publications on health effects of plastics and plasticizers in lab animals and humans. It examines problematic exposures of susceptible populations and also briefly summarizes adverse environmental impacts from plastic pollution. Ongoing efforts to steer human society toward resource conservation and sustainable consumption are discussed, including the concept of the 5 Rs--i.e., reduce, reuse, recycle, rethink, restrain--for minimizing pre- and postnatal exposures to potentially harmful components of plastics. PMID:20070188

  15. Astrocytes: Orchestrating synaptic plasticity?

    PubMed

    De Pittà, M; Brunel, N; Volterra, A

    2016-05-26

    Synaptic plasticity is the capacity of a preexisting connection between two neurons to change in strength as a function of neural activity. Because synaptic plasticity is the major candidate mechanism for learning and memory, the elucidation of its constituting mechanisms is of crucial importance in many aspects of normal and pathological brain function. In particular, a prominent aspect that remains debated is how the plasticity mechanisms, that encompass a broad spectrum of temporal and spatial scales, come to play together in a concerted fashion. Here we review and discuss evidence that pinpoints to a possible non-neuronal, glial candidate for such orchestration: the regulation of synaptic plasticity by astrocytes. PMID:25862587

  16. Ringed Accretion Disks: Instabilities

    NASA Astrophysics Data System (ADS)

    Pugliese, D.; Stuchlík, Z.

    2016-04-01

    We analyze the possibility that several instability points may be formed, due to the Paczyński mechanism of violation of mechanical equilibrium, in the orbiting matter around a supermassive Kerr black hole. We consider a recently proposed model of a ringed accretion disk, made up by several tori (rings) that can be corotating or counter-rotating relative to the Kerr attractor due to the history of the accretion process. Each torus is governed by the general relativistic hydrodynamic Boyer condition of equilibrium configurations of rotating perfect fluids. We prove that the number of the instability points is generally limited and depends on the dimensionless spin of the rotating attractor.

  17. Dislocation motion and instability

    NASA Astrophysics Data System (ADS)

    Zhu, Yichao; Chapman, Stephen Jonathan; Acharya, Amit

    2013-08-01

    The Peach-Koehler expression for the stress generated by a single (non-planar) curvilinear dislocation is evaluated to calculate the dislocation self stress. This is combined with a law of motion to give the self-induced motion of a general dislocation curve. A stability analysis of a rectilinear, uniformly translating dislocation is then performed. The dislocation is found to be susceptible to a helical instability, with the maximum growth rate occurring when the dislocation is almost, but not exactly, pure screw. The non-linear evolution of the instability is determined numerically, and implications for slip band formation and non-Schmid behavior in yielding are discussed.

  18. Varus Posteromedial Instability.

    PubMed

    Ramirez, Miguel A; Stein, Jason A; Murthi, Anand M

    2015-11-01

    Varus posteromedial instability of the elbow is a result of traumatic injury to the medial facet of the coronoid and usually the lateral collateral ligament. Treatment of these fractures is usually surgical; poor outcomes have been described with nonoperative treatment. Surgical management consists of coronoid fracture fixation with plates, screws, or sutures and radial collateral ligament repair. Outcomes of these injuries are mixed, but most series report fair to good objective scores. The purpose of this article is to describe the pathophysiology of varus posteromedial instability, discuss the management of this injury, and report the outcomes of treatment. PMID:26498545

  19. Electric Field Induced Interfacial Instabilities

    NASA Technical Reports Server (NTRS)

    Kusner, Robert E.; Min, Kyung Yang; Wu, Xiao-Lun; Onuki, Akira

    1996-01-01

    The study of the interface in a charge-free, nonpolar, critical and near-critical binary fluid in the presence of an externally applied electric field is presented. At sufficiently large fields, the interface between the two phases of the binary fluid should become unstable and exhibit an undulation with a predefined wavelength on the order of the capillary length. As the critical point is approached, this wavelength is reduced, potentially approaching length-scales such as the correlation length or critical nucleation radius. At this point the critical properties of the system may be affected. In zero gravity, the interface is unstable at all long wavelengths in the presence of a field applied across it. It is conjectured that this will cause the binary fluid to break up into domains small enough to be outside the instability condition. The resulting pattern formation, and the effects on the critical properties as the domains approach the correlation length are of acute interest. With direct observation, laser light scattering, and interferometry, the phenomena can be probed to gain further understanding of interfacial instabilities and the pattern formation which results, and dimensional crossover in critical systems as the critical fluctuations in a particular direction are suppressed by external forces.

  20. Genome instability, cancer and aging

    PubMed Central

    Maslov, Alexander Y.; Vijg, Jan

    2015-01-01

    DNA damage-driven genome instability underlies the diversity of life forms generated by the evolutionary process but is detrimental to the somatic cells of individual organisms. The cellular response to DNA damage can be roughly divided in two parts. First, when damage is severe, programmed cell death may occur or, alternatively, temporary or permanent cell cycle arrest. This protects against cancer but can have negative effects on the long term, e.g., by depleting stem cell reservoirs. Second, damage can be repaired through one or more of the many sophisticated genome maintenance pathways. However, erroneous DNA repair and incomplete restoration of chromatin after damage is resolved, produce mutations and epimutations, respectively, both of which have been shown to accumulate with age. An increased burden of mutations and/or epimutations in aged tissues increases cancer risk and adversely affects gene transcriptional regulation, leading to progressive decline in organ function. Cellular degeneration and uncontrolled cell proliferation are both major hallmarks of aging. Despite the fact that one seems to exclude the other, they both may be driven by a common mechanism. Here, we review age related changes in the mammalian genome and their possible functional consequences, with special emphasis on genome instability in stem/progenitor cells. PMID:19344750

  1. 78 FR 20640 - Polychlorinated Biphenyls (PCBs); Recycling Plastics from Shredder Residue

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-05

    ... Residue (77 FR 74006). Additional background information on recycling activities that would be affected by... AGENCY Polychlorinated Biphenyls (PCBs); Recycling Plastics from Shredder Residue AGENCY: Environmental... will generally allow for the recycling of plastic separated from shredder residue under the...

  2. Experimental assessment of unvalidated assumptions in classical plasticity theory.

    SciTech Connect

    Brannon, Rebecca Moss; Burghardt, Jeffrey A.; Bauer, Stephen J.; Bronowski, David R.

    2009-01-01

    This report investigates the validity of several key assumptions in classical plasticity theory regarding material response to changes in the loading direction. Three metals, two rock types, and one ceramic were subjected to non-standard loading directions, and the resulting strain response increments were displayed in Gudehus diagrams to illustrate the approximation error of classical plasticity theories. A rigorous mathematical framework for fitting classical theories to the data, thus quantifying the error, is provided. Further data analysis techniques are presented that allow testing for the effect of changes in loading direction without having to use a new sample and for inferring the yield normal and flow directions without having to measure the yield surface. Though the data are inconclusive, there is indication that classical, incrementally linear, plasticity theory may be inadequate over a certain range of loading directions. This range of loading directions also coincides with loading directions that are known to produce a physically inadmissible instability for any nonassociative plasticity model.

  3. Recycling of Reinforced Plastics

    NASA Astrophysics Data System (ADS)

    Adams, R. D.; Collins, Andrew; Cooper, Duncan; Wingfield-Digby, Mark; Watts-Farmer, Archibald; Laurence, Anna; Patel, Kayur; Stevens, Mark; Watkins, Rhodri

    2014-02-01

    This work has shown is that it is possible to recycle continuous and short fibre reinforced thermosetting resins while keeping almost the whole of the original material, both fibres and matrix, within the recyclate. By splitting, crushing hot or cold, and hot forming, it is possible to create a recyclable material, which we designate a Remat, which can then be used to remanufacture other shapes, examples of plates and tubes being demonstrated. Not only can remanufacturing be done, but it has been shown that over 50 % of the original mechanical properties, such as the E modulus, tensile strength, and interlaminar shear strength, can be retained. Four different forms of composite were investigated, a random mat Glass Fibre Reinforced Plastic (GFRP) bathroom component and boat hull, woven glass and carbon fibre cloth impregnated with an epoxy resin, and unidirectional carbon fibre pre-preg. One of the main factors found to affect composite recyclability was the type of resin matrix used in the composite. Thermoset resins tested were shown to have a temperature range around the Glass Transition Temperature (Tg) where they exhibit ductile behaviour, hence aiding reforming of the material. The high-grade carbon fibre prepreg was found to be less easy to recycle than the woven of random fibre laminates. One method of remanufacturing was by heating the Remat to above its glass transition temperature, bending it to shape, and then cooling it. However, unless precautions are taken, the geometric form may revert. This does not happen with the crushed material.

  4. Genomic instability, driver genes and cell selection: Projections from cancer to stem cells.

    PubMed

    Ben-David, Uri

    2015-04-01

    Cancer cells and stem cells share many traits, including a tendency towards genomic instability. Human cancers exhibit tumor-specific genomic aberrations, which often affect their malignancy and drug response. During their culture propagation, human pluripotent stem cells (hPSCs) also acquire characteristic genomic aberrations, which may have significant impact on their molecular and cellular phenotypes. These aberrations vary in size from single nucleotide alterations to copy number alterations to whole chromosome gains. A prominent challenge in both cancer and stem cell research is to identify "driver aberrations" that confer a selection advantage, and "driver genes" that underlie the recurrence of these aberrations. Following principles that are already well-established in cancer research, candidate driver genes have also been suggested in hPSCs. Experimental validation of the functional role of such candidates can uncover whether these are bona fide driver genes. The identification of driver genes may bring us closer to a mechanistic understanding of the genomic instability of stem cells. Guided by terminologies and methodologies commonly applied in cancer research, such understanding may have important ramifications for both stem cell and cancer biology. This article is part of a Special Issue entitled: Stress as a fundamental theme in cell plasticity. PMID:25132386

  5. INSTABILITIES IN THE SNS.

    SciTech Connect

    BLASKIEWICZ,M.

    1999-03-29

    The 2MW Spallation Neutron Source (SNS) will have a D.C. beam current of 40 A at extraction, making it one of the worlds most intense accelerators. Coherent instabilities are a major concern and efforts to predict beam behavior are described.

  6. Two-fluid instability

    SciTech Connect

    Stewart, H.B.

    1984-01-01

    The ability of interpenetrating flow models to represent multidimensional instabilities is probed by numerical experiments with an L-shaped two-fluid jet. Periodic and nonperiodic oscillations of various types are observed, and a partial phase portrait is constructed. The numerical experiments suggest new approaches to verifying transient interpenetrating flow models. 18 references.

  7. Electrostatic heat flux instabilities

    NASA Technical Reports Server (NTRS)

    Morrison, P. J.; Ionson, J. A.

    1980-01-01

    The electrostatic cyclotron and ion acoustic instabilities in a plasma driven by a combined heat flux and current were investigated. The minimum critical heat conduction speed (above which the plasma is unstable) is given as a function of the ratio of electron to ion temperatures.

  8. Global Linear Instability

    NASA Astrophysics Data System (ADS)

    Theofilis, Vassilios

    2011-01-01

    This article reviews linear instability analysis of flows over or through complex two-dimensional (2D) and 3D geometries. In the three decades since it first appeared in the literature, global instability analysis, based on the solution of the multidimensional eigenvalue and/or initial value problem, is continuously broadening both in scope and in depth. To date it has dealt successfully with a wide range of applications arising in aerospace engineering, physiological flows, food processing, and nuclear-reactor safety. In recent years, nonmodal analysis has complemented the more traditional modal approach and increased knowledge of flow instability physics. Recent highlights delivered by the application of either modal or nonmodal global analysis are briefly discussed. A conscious effort is made to demystify both the tools currently utilized and the jargon employed to describe them, demonstrating the simplicity of the analysis. Hopefully this will provide new impulses for the creation of next-generation algorithms capable of coping with the main open research areas in which step-change progress can be expected by the application of the theory: instability analysis of fully inhomogeneous, 3D flows and control thereof.

  9. Detecting plastics in seedcotton

    Technology Transfer Automated Retrieval System (TEKTRAN)

    To increase global market share and value the US cotton industry needs to supply cotton lint that is free of contamination. Removing plastic contamination first requires developing a means to detect plastics in seedcotton. This study was conducted to validate a custom Ion Mobility Spectrometer (IM...

  10. Reinforced plastics durability

    SciTech Connect

    Pritchard, G.

    1999-01-01

    Written especially for first-time users of reinforced plastics. The book offers substantial introductory information with key concepts. Chapters examine the long-term threats to the integrity of reinforced plastics: outdoor weathering, solvent/water attack, high temperatures, and repetitive stress.

  11. Laser processing of plastics

    NASA Astrophysics Data System (ADS)

    Atanasov, Peter A.

    1995-03-01

    CO2-laser processing of plastics has been studied experimentally and theoretically. Welding of cylindrical parts made from polycarbonate and polypropylene, cutting of polymethyl-methacrylate plates, and drilling holes in polypropylene are presented as examples. A good coincidence between theoretical and experimental results in case of laser welding has been found. Some practical aspects of laser processing of plastics has been given.

  12. Detecting plastics in seedcotton

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The US cotton industry wants to increase market share and value by supplying pure cotton. Removing contamination requires developing a means to detect plastics in seedcotton. This study was conducted to determine if Ion Mobility Spectrometry (IMS) could be used to find small amounts of plastic in ...

  13. Tracking Code for Microwave Instability

    SciTech Connect

    Heifets, S.; /SLAC

    2006-09-21

    To study microwave instability the tracking code is developed. For bench marking, results are compared with Oide-Yokoya results [1] for broad-band Q = 1 impedance. Results hint to two possible mechanisms determining the threshold of instability.

  14. Shear Instabilities in Granular Flows

    NASA Astrophysics Data System (ADS)

    Shinbrot, Troy

    2003-03-01

    Unstable waves have long been studied in fluid shear layers. These waves affect transport in the atmosphere and oceans as well as slipstream stability behind ships, planes, and heat transfer devices. Corresponding instabilities in granular flows have not previously been documented, despite the importance of these flows in geophysical and industrial systems. We report here that breaking waves can form at the interface between two streams of identical grains downstream of a splitter plate. These waves appear abruptly in flow down an inclined plane as either shear rate or angle of incline is changed, and we analyze a granular flow model that qualitatively agrees with our experimental data. The waves appear from the model to be a manifestation of a competition between shear and extensional strains in the flowing granular bed, and we propose a dimensionless group to govern the transition between steady and wavy flows.

  15. Shear instabilities in granular flows

    NASA Astrophysics Data System (ADS)

    Goldfarb, David J.; Glasser, Benjamin J.; Shinbrot, Troy

    2002-01-01

    Unstable waves have been long studied in fluid shear layers. These waves affect transport in the atmosphere and oceans, in addition to slipstream stability behind ships, aeroplanes and heat-transfer devices. Corresponding instabilities in granular flows have not been previously documented, despite the importance of these flows in geophysical and industrial systems. Here we report that breaking waves can form at the interface between two streams of identical grains flowing on an inclined plane downstream of a splitter plate. Changes in either the shear rate or the angle of incline cause such waves to appear abruptly. We analyse a granular flow model that agrees qualitatively with our experimental data; the model suggests that the waves result from competition between shear and extensional strains in the flowing granular bed. We propose a dimensionless shear number that governs the transition between steady and wavy flows.

  16. Shear instabilities in granular flows.

    PubMed

    Goldfarb, David J; Glasser, Benjamin J; Shinbrot, Troy

    2002-01-17

    Unstable waves have been long studied in fluid shear layers. These waves affect transport in the atmosphere and oceans, in addition to slipstream stability behind ships, aeroplanes and heat-transfer devices. Corresponding instabilities in granular flows have not been previously documented, despite the importance of these flows in geophysical and industrial systems. Here we report that breaking waves can form at the interface between two streams of identical grains flowing on an inclined plane downstream of a splitter plate. Changes in either the shear rate or the angle of incline cause such waves to appear abruptly. We analyse a granular flow model that agrees qualitatively with our experimental data; the model suggests that the waves result from competition between shear and extensional strains in the flowing granular bed. We propose a dimensionless shear number that governs the transition between steady and wavy flows. PMID:11797003

  17. Track recording plastic compositions

    NASA Technical Reports Server (NTRS)

    Tarle, Gregory (Inventor)

    1983-01-01

    Improved nuclear track recording plastic compositions are provided which exhibit greatly decreased surface roughness when etched to produce visible tracks of energetic nuclear particles which have passed into and/or through said plastic. The improved compositions incorporate a small quantity of a phthalic acid ester into the major plastic component which is derived from the polymerization of monomeric di-ethylene glycol bis allyl carbonate. Di-substituted phthalic acid esters are preferred as the added component, with the further perference that the ester substituent has a chain length of 2 or more carbon atoms. The inclusion of the phthalic acid ester to an extent of from about 1-2% by weight of the plastic compositions is sufficient to drastically reduce the surface roughness ordinarily produced when the track recording plastic is contacted by etchants.

  18. Plastic Surgery for Ethnic Patients

    MedlinePlus

    ... Briefing Papers > Plastic Surgery for Ethnic Patients Briefing Paper: Plastic Surgery for Ethnic Patients More than 3. ... 2067-2071. Share Related Links Plastic Surgery Briefing Papers Menu Cosmetic Reconstructive Patient Safety Before & After Find ...

  19. American Society of Plastic Surgeons

    MedlinePlus

    ... doctor who is a member of the American Society of Plastic Surgeons (ASPS®), you can rest assured ... ASPS The Plastic Surgery Foundation Copyright © 2016 American Society of Plastic Surgeons | Privacy Policy | Sitemap | Terms and ...

  20. Pair instability supernovae of very massive population III stars

    SciTech Connect

    Chen, Ke-Jung; Woosley, Stan; Heger, Alexander; Almgren, Ann; Whalen, Daniel J.

    2014-09-01

    Numerical studies of primordial star formation suggest that the first stars in the universe may have been very massive. Stellar models indicate that non-rotating Population III stars with initial masses of 140-260 M {sub ☉} die as highly energetic pair-instability supernovae. We present new two-dimensional simulations of primordial pair-instability supernovae done with the CASTRO code. Our simulations begin at earlier times than previous multidimensional models, at the onset of core contraction, to capture any dynamical instabilities that may be seeded by core contraction and explosive burning. Such instabilities could enhance explosive yields by mixing hot ash with fuel, thereby accelerating nuclear burning, and affect the spectra of the supernova by dredging up heavy elements from greater depths in the star at early times. Our grid of models includes both blue supergiants and red supergiants over the range in progenitor mass expected for these events. We find that fluid instabilities driven by oxygen and helium burning arise at the upper and lower boundaries of the oxygen shell ∼20-100 s after core bounce. Instabilities driven by burning freeze out after the SN shock exits the helium core. As the shock later propagates through the hydrogen envelope, a strong reverse shock forms that drives the growth of Rayleigh-Taylor instabilities. In red supergiant progenitors, the amplitudes of these instabilities are sufficient to mix the supernova ejecta.

  1. Synaptic plasticity and phosphorylation

    PubMed Central

    Lee, Hey-Kyoung

    2009-01-01

    A number of neuronal functions, including synaptic plasticity, depend on proper regulation of synaptic proteins, many of which can be rapidly regulated by phosphorylation. Neuronal activity controls the function of these synaptic proteins by exquisitely regulating the balance of various protein kinase and protein phosphatase activity. Recent understanding of synaptic plasticity mechanisms underscores important roles that these synaptic phosphoproteins play in regulating both pre- and post-synaptic functions. This review will focus on key postsynaptic phosphoproteins that have been implicated to play a role in synaptic plasticity. PMID:16904750

  2. Genomic Instability and Cancer

    PubMed Central

    Yao, Yixin; Dai, Wei

    2014-01-01

    Genomic instability is a characteristic of most cancer cells. It is an increased tendency of genome alteration during cell division. Cancer frequently results from damage to multiple genes controlling cell division and tumor suppressors. It is known that genomic integrity is closely monitored by several surveillance mechanisms, DNA damage checkpoint, DNA repair machinery and mitotic checkpoint. A defect in the regulation of any of these mechanisms often results in genomic instability, which predisposes the cell to malignant transformation. Posttranslational modifications of the histone tails are closely associated with regulation of the cell cycle as well as chromatin structure. Nevertheless, DNA methylation status is also related to genomic integrity. We attempt to summarize recent developments in this field and discuss the debate of driving force of tumor initiation and progression. PMID:25541596

  3. Open field lines instabilities

    SciTech Connect

    Pozzoli, R. |

    1995-09-01

    The results of some recent theoretical papers dealing with flute-like instabilities in the scrape-off layer of a tokamak with limiter configuration, where the magnetic field intersects conducting walls, are briefly recalled. Attention is then paid to the instability driven by the electron temperature gradient across the field in conjunction with the formation of the Debye sheath at the boundary, and to the effects due to the inclination of the end walls with respect to the magnetic field. When a divertor configuration is considered, important modifications are found owing to the strong deformations of the flux tubes passing near the {ital x}-point, which contrast the onset of flute-like perturbations, and to the stochasticity of field lines that can be excited by magnetic field perturbations. {copyright} {ital 1995 American Institute of Physics.}

  4. Beam-beam instability

    SciTech Connect

    Chao, A.W.

    1983-08-01

    The subject of beam-beam instability has been studied since the invention of the colliding beam storage rings. Today, with several colliding beam storage rings in operation, it is not yet fully understood and remains an outstanding problem for the storage ring designers. No doubt that good progress has been made over the years, but what we have at present is still rather primitive. It is perhaps possible to divide the beam-beam subject into two areas: one on luminosity optimization and another on the dynamics of the beam-beam interaction. The former area concerns mostly the design and operational features of a colliding beam storage ring, while the later concentrates on the experimental and theoretical aspects of the beam-beam interaction. Although both areas are of interest, our emphasis is on the second area only. In particular, we are most interested in the various possible mechanisms that cause the beam-beam instability.

  5. Whistler modulational instability.

    NASA Technical Reports Server (NTRS)

    Brinca, A. L.

    1973-01-01

    Derivation of the modulational instability characteristics of whistlers in cold and hot plasmas. The cold-plasma analysis considers both ion motion and relativistic effects; the unstable band, with a growth rate proportional to (B/B sub zero)squared, is contiguous to Omega sub e/4 and, depending on the plasma density, lies above or below that frequency (Omega sub e is the electron cyclotron frequency of the static magnetic field; B and B sub zero are the whistler and static magnetic fields). In hot plasmas, stability occurs between Omega sub e/4 and Omega prime (less than Omega sub e), with Omega prime depending mainly on the mean energy and anisotropy of the energetic electron population; the complementary unstable band has a growth rate proportional to (B/B sub zero) to the 1/2 power. The relevance of the instability to whistlers in the magnetosphere is discussed.

  6. Robust dynamic mitigation of instabilities

    SciTech Connect

    Kawata, S.; Karino, T.

    2015-04-15

    A dynamic mitigation mechanism for instability growth was proposed and discussed in the paper [S. Kawata, Phys. Plasmas 19, 024503 (2012)]. In the present paper, the robustness of the dynamic instability mitigation mechanism is discussed further. The results presented here show that the mechanism of the dynamic instability mitigation is rather robust against changes in the phase, the amplitude, and the wavelength of the wobbling perturbation applied. Generally, instability would emerge from the perturbation of the physical quantity. Normally, the perturbation phase is unknown so that the instability growth rate is discussed. However, if the perturbation phase is known, the instability growth can be controlled by a superposition of perturbations imposed actively: If the perturbation is induced by, for example, a driving beam axis oscillation or wobbling, the perturbation phase could be controlled, and the instability growth is mitigated by the superposition of the growing perturbations.

  7. Pair-Instability Supernovae of Non-Zero Metallicity Stars

    NASA Astrophysics Data System (ADS)

    Chen, K.-J.; Heger, A.; Woosley, S.; Almgren, A.; Whalen, D. J.

    2015-10-01

    Observational evidence suggests that some very massive stars in the local Universe may die as pair-instability supernovae. We present 2D simulations of the pair-instability supernova of a non-zero metallicity star. We find that very little mixing occurs in this explosion because metals in the stellar envelope drive strong winds that strip the hydrogen envelope from the star prior to death. Consequently, a reverse shock cannot form and trigger fluid instabilities during the supernova. Only weak mixing driven by nuclear burning occurs in the earliest stages of the supernova, and it is too weak to affect the observational signatures of the explosion.

  8. Combustion instability analysis

    NASA Technical Reports Server (NTRS)

    Chung, T. J.

    1990-01-01

    A theory and computer program for combustion instability analysis are presented. The basic theoretical foundation resides in the concept of entropy-controlled energy growth or decay. Third order perturbation expansion is performed on the entropy-controlled acoustic energy equation to obtain the first order integrodifferential equation for the energy growth factor in terms of the linear, second, and third order energy growth parameters. These parameters are calculated from Navier-Stokes solutions with time averages performed on as many Navier-Stokes time steps as required to cover at least one peak wave period. Applications are made for a 1-D Navier-Stokes solution for the Space Shuttle Main Engine (SSME) thrust chamber with cross section area variations taken into account. It is shown that instability occurs when the mean pressure is set at 2000 psi with 30 percent disturbances. Instability also arises when the mean pressure is set at 2935 psi with 20 percent disturbances. The system with mean pressures and disturbances more adverse that these cases were shown to be unstable.

  9. Production of Methane and Water from Crew Plastic Waste

    NASA Technical Reports Server (NTRS)

    Captain, Janine; Santiago, Eddie; Parrish, Clyde; Strayer, Richard F.; Garland, Jay L.

    2008-01-01

    Recycling is a technology that will be key to creating a self sustaining lunar outpost. The plastics used for food packaging provide a source of material that could be recycled to produce water and methane. The recycling of these plastics will require some additional resources that will affect the initial estimate of starting materials that will have to be transported from earth, mainly oxygen, energy and mass. These requirements will vary depending on the recycling conditions. The degredation products of these plastics will vary under different atmospheric conditions. An estimate of the the production rate of methane and water using typical ISRU processes along with the plastic recycling will be presented.

  10. Dreaming in plastic

    NASA Astrophysics Data System (ADS)

    Korzhov, Marianna; Andelman, David; Shikler, Rafi

    2008-07-01

    Plastic is one of the most versatile materials available. It is cheap, flexible and easy to process, and as a result it is all around us - from our computer keyboards to the soles of our shoes. One of its most common applications is as an insulating coating for electric wires; indeed, plastic is well known for its insulating characteristics. It came as something of a surprise, therefore, when in the late 1970s a new generation of plastics was discovered that displayed exactly the opposite behaviour - the ability to conduct electricity. In fact, plastics can be made with a whole range of conductivities - there are polymer materials that behave like semiconductors and there are those that can conduct as well as metals. This discovery sparked a revolution in the electronics community, and three decades of research effort is now yielding a range of stunning new applications for this ubiquitous material.

  11. A Plastic Menagerie

    ERIC Educational Resources Information Center

    Hadley, Mary Jane

    2010-01-01

    Bobble heads had become quite popular, depicting all sorts of sports figures, animals, and even presidents. In this article, the author describes how her fourth graders made bobble head sculptures out of empty plastic drink bottles. (Contains 1 online resource.)

  12. Shape-Shifting Plastic

    SciTech Connect

    2015-05-20

    A new plastic developed by ORNL and Washington State University transforms from its original shape through a series of temporary shapes and returns to its initial form. The shape-shifting process is controlled through changes in temperature

  13. Recycle plastics into feedstocks

    SciTech Connect

    Kastner, H.; Kaminsky, W.

    1995-05-01

    Thermal cracking of mixed-plastics wastes with a fluidized-bed reactor can be a viable and cost-effective means to meet mandatory recycling laws. Strict worldwide environmental statutes require the hydrocarbon processing industry (HPI) to develop and implement product applications and technologies that reuse post-consumer mixed-plastics waste. Recycling or reuse of plastics waste has a broad definition. Recycling entails more than mechanical regranulation and remelting of polymers for film and molding applications. A European consortium of academia and refiners have investigated if it is possible and profitable to thermally crack plastics into feedstocks for refining and petrochemical applications. Development and demonstration of pyrolysis methods show promising possibilities of converting landfill garbage into valuable feedstocks such as ethylene, propylene, BTX, etc. Fluidized-bed reactor technologies offer HPI operators a possible avenue to meet recycling laws, conserve raw materials and yield a profit. The paper describes thermal cracking for feedstocks and pyrolysis of polyolefins.

  14. Extruded plastic scintillation detectors

    SciTech Connect

    Anna Pla-Dalmau, Alan D. Bross and Kerry L. Mellott

    1999-04-16

    As a way to lower the cost of plastic scintillation detectors, commercially available polystyrene pellets have been used in the production of scintillating materials that can be extruded into different profiles. The selection of the raw materials is discussed. Two techniques to add wavelength shifting dopants to polystyrene pellets and to extrude plastic scintillating strips are described. Data on light yield and transmittance measurements are presented.

  15. Laser cutting plastic materials

    SciTech Connect

    Van Cleave, R.A.

    1980-08-01

    A 1000-watt CO/sub 2/ laser has been demonstrated as a reliable production machine tool for cutting of plastics, high strength reinforced composites, and other nonmetals. More than 40 different plastics have been laser cut, and the results are tabulated. Applications for laser cutting described include fiberglass-reinforced laminates, Kevlar/epoxy composites, fiberglass-reinforced phenolics, nylon/epoxy laminates, ceramics, and disposable tooling made from acrylic.

  16. Electric Field Induced Interfacial Instabilities

    NASA Technical Reports Server (NTRS)

    Kusner, Robert E.; Min, Kyung Yang; Wu, Xiao-lun; Onuki, Akira

    1999-01-01

    The study of the interface in a charge-free, critical and near-critical binary fluid in the presence of an externally applied electric field is presented. At sufficiently large fields, the interface between the two phases of the binary fluid should become unstable and exhibit an undulation with a predefined wavelength on the order of the capillary length. As the critical point is approached, this wavelength is reduced, potentially approaching length-scales such as the correlation length or critical nucleation radius. At this point the critical properties of the system may be affected. In this paper, the flat interface of a marginally polar binary fluid mixture is stressed by a perpendicular alternating electric field and the resulting instability is characterized by the critical electric field E(sub c) and the pattern observed. The character of the surface dynamics at the onset of instability is found to be strongly dependent on the frequency f of the field applied. The plot of E(sub c) vs. f for a fixed temperature shows a sigmoidal shape, whose low and high frequency limits are well described by a power-law relationship, E(sub c) = epsilon(exp zeta) with zeta = 0.35 and zeta = 0.08, respectively. The low-limit exponent compares well with the value zeta = 4 for a system of conducting and non-conducting fluids. On the other hand, the high-limit exponent coincides with what was first predicted by Onuki. The instability manifests itself as the conducting phase penetrates the non-conducting phase. As the frequency increases, the shape of the pattern changes from an array of bifurcating strings to an array of column-like (or rod-like) protrusions, each of which spans the space between the plane interface and one of the electrodes. For an extremely high frequency, the disturbance quickly grows into a parabolic cone pointing toward the upper plate. As a result, the interface itself changes its shape from that of a plane to that of a high sloping pyramid.

  17. Plasticity as a developing trait: exploring the implications

    PubMed Central

    2015-01-01

    Individual differences in plasticity have been classically framed as genotype-by-environment interactions, with different genotypes showing different reaction norms in response to environmental conditions. However, research has shown that early experience can be a critical factor in shaping an individual's plasticity to later environmental factors. In other words, plasticity itself can be investigated as a developing trait that reflects the combined action of an individual's genes and previous interactions with the environment. In this paper I explore some implications of the idea that the early environment modulates long-term plasticity, with an emphasis on plasticity in behavioral traits. I begin by focusing on the mechanisms that mediate plasticity at the proximate level, and discussing the possibility that some traits may work as generalized mediators of plasticity by affecting the sensitivity of multiple phenol types across developmental contexts. I then tackle the complex problem of the evolution of reaction norms for plasticity. Next, I consider a number of potential implications for research on parental effects and phenotypic matching, and conclude by discussing how plasticity may become a target of evolutionary conflict between parents and offspring. In total, I aim to show how the idea of plasticity as a developing trait offers a rich source of questions and insights that may inform future research in this area. PMID:26816522

  18. The Need for Plastics Education.

    ERIC Educational Resources Information Center

    Society of Plastics Engineers, Inc., Stamford, CT.

    In view of a lack of trained personnel in the industry, the Plastics Education Foundation proposes that educators (1) add more plastics programs, (2) establish plastics engineering degrees at appropriate 4-year institutions, (3) add plastics processing technology to current engineering curricula, and (4) interest younger students in courses and/or…

  19. Short-wave cooperative instabilities in representative aircraft vortices

    NASA Astrophysics Data System (ADS)

    Fabre, David; Jacquin, Laurent

    2004-05-01

    This paper considers the short-wave cooperative instabilities in a family of vortices representative of aircraft wakes. These vortices are characterized by two core scales, an internal core scale a1 and an external core scale a2, and their azimuthal velocity follows a power law V(r)˜r-α in the intermediate zone (a1instability theory. The unstable wavelengths and the structure of the unstable modes are characterized as functions of the base flow parameters α and a2/a1. For 0.5⩽α⩽1, the wavelength of the instability is of the order of the internal scale a1 and the unstable modes only affect the internal core. In this case the growth rate of the instability is in accordance with the predictions of the elliptical instability theory and is a growing function of the parameter a2/a1. For 0⩽α<0.4, the wavelength of the instability is of the order of the external scale a2 and the unstable modes extend into the intermediate zone. In this case the growth rate of the instability differs from the predictions of the elliptical instability theory and is independent upon the parameter a2/a1. Interestingly, a sharp transition between these two regimes occurs for 0.4<α<0.5, in a range of parameters corresponding to experimentally measured trailing wakes. In this range, the bands of wave numbers affected by the instability are particularly large and may coalesce into a broadband spectrum.

  20. Astrophysical Weibel instability in counterstreaming laser-produced plasmas

    NASA Astrophysics Data System (ADS)

    Fox, William; Fiksel, Gennady; Bhattacharjee, Amitava; Change, Po-Yu; Germaschewski, Kai; Hu, Suxing; Nilson, Philip

    2014-06-01

    Astrophysical shock waves play diverse roles, including energizing cosmic rays in the blast waves of astrophysical explosions, and generating primordial magnetic fields during the formation of galaxies and clusters. These shocks are typically collisionless and require collective electromagnetic fields to couple the upstream and downstream plasmas. The Weibel instability has been proposed to provide the requisite interaction mechanism for shock formation in weakly-magnetized shocks by generating turbulent electric and magnetic fields in the shock front. This work presents the first laboratory identification of this Weibel instability between counterstreaming supersonic plasma flows and confirms its basic features, a significant step towards understanding these shocks. In the experiments, conducted on the OMEGA EP laser facility at the University of Rochester, a pair of plasmas plumes are generated by irradiating of a pair of opposing parallel plastic (CH) targets. The ion-ion interaction between the two plumes is collisionless, so as the plumes interpenetrate, supersonic, counterstreaming ion flow conditions are obtained. Electromagnetic fields formed in the interaction of the two plumes were probed with an ultrafast laser-driven proton beam, and we observed the growth of a highly striated, transverse instability with extended filaments parallel to the flows. The instability is identified as an ion-driven Weibel instability through agreement with analytic theory and particle-in-cell simulations, paving the way for further detailed laboratory study of this instability and its consequences for particle energization and shock formation.[1] W. Fox, G. Fiksel, A. Bhattacharjee, P. Y. Chang, K. Germaschewski, S. X. Hu, and P. M. Nilson, “Filamentation instability of counterstreaming laser-driven plasmas,” Phys. Rev. Lett. 111, 225002 (2013).

  1. Elastic and plastic effects on heterogeneous nucleation and nanowire formation

    NASA Astrophysics Data System (ADS)

    Boussinot, G.; Schulz, R.; Hüter, C.; Brener, E. A.; Spatschek, R.

    2014-02-01

    We investigate theoretically the effects of elastic and plastic deformations on heterogeneous nucleation and nanowire formation. In the first case, the influence of the confinement of the critical nucleus between two parallel misfitting substrates is investigated using scaling arguments. We present phase diagrams giving the nature of the nucleation regime as a function of the driving force and the degree of confinement. We complement this analytical study by amplitude equations simulations. In the second case, the influence of a screw dislocation inside a nanowire on the development of the morphological surface instability of the wire, related to the Rayleigh-Plateau instability, is examined. Here the screw dislocation provokes a torsion of the wire known as Eshelby twist. Numerical calculations using the finite element method and the amplitude equations are performed to support analytical investigations. It is shown that the screw dislocation promotes the Rayleigh-Plateau instability.

  2. Radiation Induced Genomic Instability

    SciTech Connect

    Morgan, William F.

    2011-03-01

    Radiation induced genomic instability can be observed in the progeny of irradiated cells multiple generations after irradiation of parental cells. The phenotype is well established both in vivo (Morgan 2003) and in vitro (Morgan 2003), and may be critical in radiation carcinogenesis (Little 2000, Huang et al. 2003). Instability can be induced by both the deposition of energy in irradiated cells as well as by signals transmitted by irradiated (targeted) cells to non-irradiated (non-targeted) cells (Kadhim et al. 1992, Lorimore et al. 1998). Thus both targeted and non-targeted cells can pass on the legacy of radiation to their progeny. However the radiation induced events and cellular processes that respond to both targeted and non-targeted radiation effects that lead to the unstable phenotype remain elusive. The cell system we have used to study radiation induced genomic instability utilizes human hamster GM10115 cells. These cells have a single copy of human chromosome 4 in a background of hamster chromosomes. Instability is evaluated in the clonal progeny of irradiated cells and a clone is considered unstable if it contains three or more metaphase sub-populations involving unique rearrangements of the human chromosome (Marder and Morgan 1993). Many of these unstable clones have been maintained in culture for many years and have been extensively characterized. As initially described by Clutton et al., (Clutton et al. 1996) many of our unstable clones exhibit persistently elevated levels of reactive oxygen species (Limoli et al. 2003), which appear to be due dysfunctional mitochondria (Kim et al. 2006, Kim et al. 2006). Interestingly, but perhaps not surprisingly, our unstable clones do not demonstrate a “mutator phenotype” (Limoli et al. 1997), but they do continue to rearrange their genomes for many years. The limiting factor with this system is the target – the human chromosome. While some clones demonstrate amplification of this chromosome and thus lend

  3. Acute hypoxia differentially affects the NMDA receptor NR1, NR2A and NR2B subunit mRNA levels in the developing chick optic tectum: stage-dependent plasticity in the 2B-2A ratio.

    PubMed

    Vacotto, Marina; Rapacioli, Melina; Flores, Vladimir; de Plazas, Sara Fiszer

    2010-10-01

    It is known that the NMDA-R NR1 subunit is needed for the receptor activity and that under hypoxia the evolution toward apoptosis or neuronal survival depends on the balance NR2A/NR2B subunits. This paper analyzes the effect of acute hypoxia on the above mentioned subunits mRNAs during development. The mean percentage of NR1+ neurons displayed the higher plasticity during development while the NR2A+ neurons the higher stability. Acute hypoxia increased the mean percentage of NR1+ and NR2B+ neurons at ED12 but only that of NR1+ neurons at ED18. Acute hypoxia increased the levels of expression of NR1 and NR2B mRNAs at ED12 without changes in the NR2A mRNA. During early stages there is a higher sensitivity to change the subunits mRNA levels under a hypoxic treatment. At ED12 acute hypoxia increased the probability of co-expression of the NR1-NR2A and NR1-NR2B subunits combinations, the level of NR1 and NR2B and the ratio NR2B/NR2A. These conditions facilitate the evolution towards apoptosis. PMID:20596770

  4. Genome instability and aging.

    PubMed

    Vijg, Jan; Suh, Yousin

    2013-01-01

    Genome instability has long been implicated as the main causal factor in aging. Somatic cells are continuously exposed to various sources of DNA damage, from reactive oxygen species to UV radiation to environmental mutagens. To cope with the tens of thousands of chemical lesions introduced into the genome of a typical cell each day, a complex network of genome maintenance systems acts to remove damage and restore the correct base pair sequence. Occasionally, however, repair is erroneous, and such errors, as well as the occasional failure to correctly replicate the genome during cell division, are the basis for mutations and epimutations. There is now ample evidence that mutations accumulate in various organs and tissues of higher animals, including humans, mice, and flies. What is not known, however, is whether the frequency of these random changes is sufficient to cause the phenotypic effects generally associated with aging. The exception is cancer, an age-related disease caused by the accumulation of mutations and epimutations. Here, we first review current concepts regarding the relationship between DNA damage, repair, and mutation, as well as the data regarding genome alterations as a function of age. We then describe a model for how randomly induced DNA sequence and epigenomic variants in the somatic genomes of animals can result in functional decline and disease in old age. Finally, we discuss the genetics of genome instability in relation to longevity to address the importance of alterations in the somatic genome as a causal factor in aging and to underscore the opportunities provided by genetic approaches to develop interventions that attenuate genome instability, reduce disease risk, and increase life span. PMID:23398157

  5. Planetesimal Formation through the Streaming Instability

    NASA Astrophysics Data System (ADS)

    Yang, Chao-Chin; Johansen, Anders; Schäfer, Urs

    2015-12-01

    The streaming instability is a promising mechanism to circumvent the barriers in direct dust growth and lead to the formation of planetesimals, as demonstrated by many previous studies. In order to resolve the thin layer of solids, however, most of these studies were focused on a local region of a protoplanetary disk with a limited simulation domain. It remains uncertain how the streaming instability is affected by the disk gas on large scales, and models that have sufficient dynamical range to capture both the thin particle layer and the large-scale disk dynamics are required.We hereby systematically push the limits of the computational domain up to more than the gas scale height, and study the particle-gas interaction on large scales in the saturated state of the streaming instability and the initial mass function of the resulting planetesimals. To overcome the numerical challenges posed by this kind of models, we have developed a new technique to simultaneously relieve the stringent time step constraints due to small-sized particles and strong local solid concentrations. Using these models, we demonstrate that the streaming instability can drive multiple radial, filamentary concentrations of solids, implying that planetesimals are born in well separated belt-like structures. We also find that the initial mass function of planetesimals via the streaming instability has a characteristic exponential form, which is robust against computational domain as well as resolution. These findings will help us further constrain the cosmochemical history of the Solar system as well as the planet formation theory in general.

  6. Gas turbine combustion instability

    SciTech Connect

    Richards, G.A.; Lee, G.T.

    1996-09-01

    Combustion oscillations are a common problem in development of LPM (lean premix) combustors. Unlike earlier, diffusion style combustors, LPM combustors are especially susceptible to oscillations because acoustic losses are smaller and operation near lean blowoff produces a greater combustion response to disturbances in reactant supply, mixing, etc. In ongoing tests at METC, five instability mechanisms have been identified in subscale and commercial scale nozzle tests. Changes to fuel nozzle geometry showed that it is possible to stabilize combustion by altering the timing of the feedback between acoustic waves and the variation in heat release.

  7. Surface instabilities and nuclear multifragmentation

    SciTech Connect

    Moretto, L.G.; Tso, K.; Colonna, N.; Wozniak, G.J.

    1992-03-01

    Central heavy-ion collisions, as described by a Boltzman-Nordheim-Vlasov calculation, form nuclear disks that break up into several fragments due to surface instabilities of the Rayleigh-Taylor kind. We demonstrate that a sheet of liquid, nuclear or otherwise, stable in the limit of infinitely sharp surfaces, becomes unstable due to surface-surface interactions. The onset of this instability is determined analytically. The relevance of these instabilities to nuclear multifragmentation is discussed.

  8. Plastic Deformation Modes of CuZr/Cu Multilayers

    NASA Astrophysics Data System (ADS)

    Cui, Yan; Abad, Oscar Torrents; Wang, Fei; Huang, Ping; Lu, Tian-Jian; Xu, Ke-Wei; Wang, Jian

    2016-03-01

    We synthesized CuZr/Cu multilayers and performed nanoindentation testing to explore the dependence of plastic deformation modes on the thickness of CuZr layers. The Cu layers were 18 nm thick and the CuZr layers varied in thickness from 4 nm to 100 nm. We observed continuous plastic co-deformation in the 4 nm and 10 nm CuZr ‑ 18 nm Cu multilayers and plastic-induced shear instability in thick CuZr layers (>20 nm). The plastic co-deformation is ascribed to the nucleation and interaction of shear transformation zones in CuZr layers at the adjacent interfaces, while the shear instability is associated with the nucleation and propagation of shear bands in CuZr layers. Shear bands are initialized in the CuZr layers due to the accumulated glide dislocations along CuZr-Cu interfaces, and propagate into adjacent Cu layers via slips on {111} plane non-parallel to the interface. Due to crystallographic constraint of the Cu layers, shear bands are approximately parallel to {111} plane in the Cu layer.

  9. Plastic Deformation Modes of CuZr/Cu Multilayers.

    PubMed

    Cui, Yan; Abad, Oscar Torrents; Wang, Fei; Huang, Ping; Lu, Tian-Jian; Xu, Ke-Wei; Wang, Jian

    2016-01-01

    We synthesized CuZr/Cu multilayers and performed nanoindentation testing to explore the dependence of plastic deformation modes on the thickness of CuZr layers. The Cu layers were 18 nm thick and the CuZr layers varied in thickness from 4 nm to 100 nm. We observed continuous plastic co-deformation in the 4 nm and 10 nm CuZr - 18 nm Cu multilayers and plastic-induced shear instability in thick CuZr layers (>20 nm). The plastic co-deformation is ascribed to the nucleation and interaction of shear transformation zones in CuZr layers at the adjacent interfaces, while the shear instability is associated with the nucleation and propagation of shear bands in CuZr layers. Shear bands are initialized in the CuZr layers due to the accumulated glide dislocations along CuZr-Cu interfaces, and propagate into adjacent Cu layers via slips on {111} plane non-parallel to the interface. Due to crystallographic constraint of the Cu layers, shear bands are approximately parallel to {111} plane in the Cu layer. PMID:26984537

  10. Plastic Deformation Modes of CuZr/Cu Multilayers

    PubMed Central

    Cui, Yan; Abad, Oscar Torrents; Wang, Fei; Huang, Ping; Lu, Tian-Jian; Xu, Ke-Wei; Wang, Jian

    2016-01-01

    We synthesized CuZr/Cu multilayers and performed nanoindentation testing to explore the dependence of plastic deformation modes on the thickness of CuZr layers. The Cu layers were 18 nm thick and the CuZr layers varied in thickness from 4 nm to 100 nm. We observed continuous plastic co-deformation in the 4 nm and 10 nm CuZr − 18 nm Cu multilayers and plastic-induced shear instability in thick CuZr layers (>20 nm). The plastic co-deformation is ascribed to the nucleation and interaction of shear transformation zones in CuZr layers at the adjacent interfaces, while the shear instability is associated with the nucleation and propagation of shear bands in CuZr layers. Shear bands are initialized in the CuZr layers due to the accumulated glide dislocations along CuZr-Cu interfaces, and propagate into adjacent Cu layers via slips on {111} plane non-parallel to the interface. Due to crystallographic constraint of the Cu layers, shear bands are approximately parallel to {111} plane in the Cu layer. PMID:26984537

  11. Developmental plasticity and the origin of tetrapods.

    PubMed

    Standen, Emily M; Du, Trina Y; Larsson, Hans C E

    2014-09-01

    The origin of tetrapods from their fish antecedents, approximately 400 million years ago, was coupled with the origin of terrestrial locomotion and the evolution of supporting limbs. Polypterus is a member of the basal-most group of ray-finned fish (actinopterygians) and has many plesiomorphic morphologies that are comparable to elpistostegid fishes, which are stem tetrapods. Polypterus therefore serves as an extant analogue of stem tetrapods, allowing us to examine how developmental plasticity affects the 'terrestrialization' of fish. We measured the developmental plasticity of anatomical and biomechanical responses in Polypterus reared on land. Here we show the remarkable correspondence between the environmentally induced phenotypes of terrestrialized Polypterus and the ancient anatomical changes in stem tetrapods, and we provide insight into stem tetrapod behavioural evolution. Our results raise the possibility that environmentally induced developmental plasticity facilitated the origin of the terrestrial traits that led to tetrapods. PMID:25162530

  12. The plasticity of clays

    USGS Publications Warehouse

    Group, F.F.

    1905-01-01

    (1) Sand injures plasticity little at first because the grains are suspended in a plastic mass. It is only when grains are abundant enough to come in contact with their neighbors, that the effect becomes serious, and then both strength and amount of possible flow are injured. (2) Certain rare organic colloids increase the plasticity by rendering the water viscous. (3) Fineness also tends to increase plasticity. (4) Plane surfaces (plates) increase the amount of possible flow. They also give a chance for lubrication by thinner films, thus increasing the friction of film, and the strength of the whole mass. The action of plates is thus twofold ; but fineness may be carried to such an extent as to break up plate-like grains into angular fragments. The beneficial effects of plates are also decreased by the fact that each is so closely surrounded by others in the mass. (5) Molecular attraction is twofold in increasing plasticity. As the attraction increases, the coherence and strength of the mass increase, and the amount of possible deformation before crumbling also increases. Fineness increases this action by requiring more water. Colloids and crystalloids in solution may also increase the attraction. It is thus seen to be more active than any other single factor.

  13. Pump instability phenomena generated by fluid forces

    NASA Technical Reports Server (NTRS)

    Gopalakrishnan, S.

    1985-01-01

    Rotor dynamic behavior of high energy centrifugal pumps is significantly affected by two types of fluid forces; one due to the hydraulic interaction of the impeller with the surrounding volute or diffuser and the other due to the effect of the wear rings. The available data on these forces is first reviewed. A simple one degree-of-freedom system containing these forces is analytically solved to exhibit the rotor dynamic effects. To illustrate the relative magnitude of these phenomena, an example of a multistage boiler feed pump is worked out. It is shown that the wear ring effects tend to suppress critical speed and postpone instability onset. But the volute-impeller forces tend to lower the critical speed and the instability onset speed. However, for typical boiler feed pumps under normal running clearances, the wear ring effects are much more significant than the destabilizing hydraulic interaction effects.

  14. Instabilities of wrinkled membranes with pressure loadings

    NASA Astrophysics Data System (ADS)

    Patil, Amit; Nordmark, Arne; Eriksson, Anders

    2016-09-01

    Wrinkling can affect the functionality of thin membranes subjected to various loadings or boundary conditions. The concept of relaxed strain energy was studied for isotropic, hyperelastic, axisymmetric membranes pressurized by gas or fluid. Non-intuitive instabilities were observed when axisymmetric wrinkled membranes were perturbed with angle dependent displacement fields. A linearized theory showed that static equilibrium states of pressurized membranes, modelled by a relaxed strain energy formulation, are unstable, when the wrinkled surface is subjected to pressure loadings. The theory is extended to the non-axisymmetric membranes and it is shown that these instabilities are local phenomena. Simulations for the pressurized cylindrical membranes with non-uniform thickness and hemispherical membranes support the claims in both theoretical and numerical contexts including finite element simulations.

  15. Study of cavitating inducer instabilities

    NASA Technical Reports Server (NTRS)

    Young, W. E.; Murphy, R.; Reddecliff, J. M.

    1972-01-01

    An analytic and experimental investigation into the causes and mechanisms of cavitating inducer instabilities was conducted. Hydrofoil cascade tests were performed, during which cavity sizes were measured. The measured data were used, along with inducer data and potential flow predictions, to refine an analysis for the prediction of inducer blade suction surface cavitation cavity volume. Cavity volume predictions were incorporated into a linearized system model, and instability predictions for an inducer water test loop were generated. Inducer tests were conducted and instability predictions correlated favorably with measured instability data.

  16. Editorial Commentary: Multidirectional Shoulder Instability.

    PubMed

    Lubowitz, James H

    2015-12-01

    Multidirectional shoulder instability responds to physical therapy and rehabilitation. For patients who fail rehabilitation, arthroscopic capsular plication seems the treatment of choice. PMID:26652151

  17. PARTIAL TORUS INSTABILITY

    SciTech Connect

    Olmedo, Oscar; Zhang Jie

    2010-07-20

    Flux ropes are now generally accepted to be the magnetic configuration of coronal mass ejections (CMEs), which may be formed prior to or during solar eruptions. In this study, we model the flux rope as a current-carrying partial torus loop with its two footpoints anchored in the photosphere, and investigate its stability in the context of the torus instability (TI). Previous studies on TI have focused on the configuration of a circular torus and revealed the existence of a critical decay index of the overlying constraining magnetic field. Our study reveals that the critical index is a function of the fractional number of the partial torus, defined by the ratio between the arc length of the partial torus above the photosphere and the circumference of a circular torus of equal radius. We refer to this finding as the partial torus instability (PTI). It is found that a partial torus with a smaller fractional number has a smaller critical index, thus requiring a more gradually decreasing magnetic field to stabilize the flux rope. On the other hand, a partial torus with a larger fractional number has a larger critical index. In the limit of a circular torus when the fractional number approaches 1, the critical index goes to a maximum value. We demonstrate that the PTI helps us to understand the confinement, growth, and eventual eruption of a flux-rope CME.

  18. Core Characteristics Deterioration due to Plastic Deformation

    NASA Astrophysics Data System (ADS)

    Kaido, Chikara; Arai, Satoshi

    This paper discusses the effect of plastic deformation at core manufacturing on the characteristics of cores where non-oriented electrical steel sheets are used as core material. Exciting field and iron loss increase proportionally to plastic deformation in the case of rP<10, where rP is a ratio of plastic deformation to that at yield point. In this region, anomalous eddy currents increase because plastic deformations of crystalline grains are distributed and then the flux distribution is induced. In the case of rP>20, the deterioration tend to saturate, and the increases in magnetic field and iron loss are 1000 to 1500A/m and 2 to 4W/kg. They are related to grain size, and high grade with larger grain may have lager field increase and smaller iron loss increase. Anomalous eddy current losses scarcely increase in this region. In actual motors, the plastic deformation affects iron loss increase although exciting current increases a little.

  19. Instability characteristics of fluidelastic instability of tube rows in crossflow

    SciTech Connect

    Chen, S.S.; Jendrzejczyk, J.A.

    1986-04-01

    An experimental study is reported to investigate the jump phenomenon in critical flow velocities for tube rows with different pitch-to-diameter ratios and the excited and intrinsic instabilities for a tube row with a pitch-to-diameter ratio of 1.75. The experimental data provide additional insights into the instability phenomena of tube arrays in crossflow. 9 refs., 10 figs.

  20. Instability vaccination: A structural design to reduce Rayleigh Taylor instability

    NASA Astrophysics Data System (ADS)

    Esmaeili, Amin

    2013-10-01

    Instability vaccination can be defined as designing a structure to stimulate the system in order to develop immunity against its instability. In this work we have tried to do this stabilization by a new technique. Previously some suppression of R-M instability was done by insertion of magnetic field, but in this work we have tried to do this suppression by proposing a configuration similar to the shape of instability, we call it instability vaccination. This design will reduce the rotations (mostly rotations of Rayleigh Taylor instability) in the fluids that cause more mixing and instabilities. In this paper, we consider the evolution of the interface between two ideal semi-infinite fluid surfaces, using two-dimensional Riemann solver, to solve the Euler equations. First, we performed evolution of a rectangular disorder between the 2 surfaces using two-dimensional Riemann problem for the equations of Euler. Next, the interface was replaced with a perturbation that was part rectangular and part semi-circular (like a mushroom). The simulation was continued till some time steps using the HLL method. We have seen that the rotations of Rayleigh Taylor (R-T) instability were decreased in the second case. Email: amin@cavelab.cs.tsukuba.ac.jp

  1. Consumer hazards of plastics.

    PubMed Central

    Wiberg, G S

    1976-01-01

    The modern consumer is exposed to a wide variety of plastic and rubber products in his day to day life: at home, work, school, shopping, recreation and play, and transport. A large variety of toxic sequellae have resulted from untoward exposures by many different routes: oral, dermal, inhalation, and parenteral. Toxic change may result from the plastic itself, migration of unbound components and additives, chemical decomposition or toxic pyrolysis products. The type of damage may involve acute poisoning, chronic organ damage, reproductive disorders, and carcinogenic, mutagenic and teratogenic episodes. Typical examples for all routes are cited along with the activites of Canadian regulatory agencies to reduce both the incidence and severity of plastic-induced disease. PMID:1026409

  2. Molecular dynamics simulations of dislocation instability in a stress gradient

    NASA Astrophysics Data System (ADS)

    Li, Ming; Selinger, Robin L.

    2003-04-01

    We present simulation studies of a morphological instability arising in dislocation dynamics. When an initially straight dislocation line is driven by a stress whose magnitude grows along the direction of dislocation motion, vibrational modes of the dislocation line with wavelength above a threshold value become linearly unstable. Molecular dynamics simulation studies of screw dislocations in Al demonstrate the onset of the instability during dislocation pair annihilation and annihilation at a crack tip. The wavelength of the unstable vibrational mode observed in each case agrees with the predictions of theoretical analysis. We discuss the role of temperature in nucleating the instability and speculate about how instabilities in dislocation motion could affect the density of threading dislocations during growth of heteroepitaxial thin films.

  3. Magnetorotational instability in plasmas with mobile dust grains

    SciTech Connect

    Ren Haijun; Cao Jintao; Li Ding; Chu, Paul K.

    2013-03-15

    The magnetorotational instability of dusty plasmas is investigated using the multi-fluid model and the general dispersion relation is derived based on local approximation. The dust grains are found to play an important role in the dispersion relation in the low-frequency mode and exhibit destabilizing effects on the plasma. Both the instability criterion and growth rate are affected significantly by the dust and when the dust is heavy enough to be unperturbed, the reduced dispersion relations are obtained. The instability criteria show that the dust grains have stabilizing effects on the instability when the rotation frequency decreases outwards and conversely lead to destabilizing effects when the rotation frequency increases outwards. The results are relevant to accession and protoplanetary disks.

  4. Plastic heliostat enclosure analysis

    NASA Astrophysics Data System (ADS)

    Berry, M. J.

    1984-12-01

    The conceptual design and cost analysis of an enclosed plastic heliostat for a 50-MW/sub e/ central receiver solar thermal electric power plant are presented. The purpose of the study was to analyze the most recent design of the Boeing enclosed plastic heliostat for cost and compare results with a reference second generation glass heliostat case provided by Sandia National Laboratories, Livermore. In addition, sensitivities of busbar energy costs to variations in capital cost (installed cost), operation and maintenance most and overall reflectivity were evaluated.

  5. The plasticity of social emotions.

    PubMed

    Klimecki, Olga M

    2015-01-01

    Social emotions such as empathy or compassion greatly facilitate our interactions with others. Despite the importance of social emotions, scientific studies have only recently revealed functional neural plasticity associated with the training of such emotions. Using the framework of two antagonistic neural systems, the threat and social disconnection system on the one hand, and the reward and social connection system on the other, this article describes how training compassion and empathy can change the functioning of these systems in a targeted manner. Whereas excessive empathic sharing of suffering can increase negative feelings and activations in the insula and anterior cingulate cortex (corresponding to the threat and social disconnection system), compassion training can strengthen positive affect and neural activations in the medial orbitofrontal cortex and striatum (corresponding to the reward and social connection system). These neuroimaging findings are complemented by results from behavioral studies showing that compassion is linked to helping and forgiveness behavior, whereas empathic distress not only decreases helping behavior, but is even associated with increased aggressive behavior. Taken together, these data provide encouraging evidence for the plasticity of adaptive social emotions with wide-ranging implications for basic science and applied settings. PMID:26369728

  6. A model for self-treatment of four sub-types of symptomatic 'depression' using non-prescription agents: neuroticism (anxiety and emotional instability); malaise (fatigue and painful symptoms); demotivation (anhedonia) and seasonal affective disorder 'SAD'.

    PubMed

    Charlton, Bruce G

    2009-01-01

    This article will present a model for how 'depression' (i.e. depressive symptoms) can be divided into four self-diagnosed sub-types or causes which might then be self-treated using agents available without prescription. (Another, much rarer, cause of depressed symptoms is the classical illness of 'melancholia', which when severe cannot be self-treated and typically requires hospitalization.) A self-management option and alternative is now needed due to the an inappropriate emphasis of modern psychiatry on treatment of imprecise syndromal 'disorders' which may entail treating 'depression' at the cost of making the patient feel and function worse. By contrast, the basic theoretical stance of self-management is that depressed mood should be seen as a result of unpleasant symptoms - and it is the symptoms that require treatment, not the mood itself. Furthermore, drugs (or other interventions) need to be classified in terms of their potential therapeutic effects on these symptoms that may cause depressed mood. The four common causes of depressed mood considered here are the personality trait of Neuroticism; the state of malaise (fatigue, aching etc) which accompanies an illness with an activated immune system; demotivation due to lack of positive emotions (anhedonia); and the syndrome of seasonal affective disorder (SAD). Each of the four sub-types is then 'matched' with a first-line non-prescription agent. The 'stabilizing' agents such as St John's Wort and the antihistamines chlorpheniramine and diphenhydramine are used for treatment of Neuroticism; analgesics/pain killers such as aspirin, ibuprofen, paracetamol/acetaminophen and the opiates are used to treat malaise; energizing agents such as caffeine and nicotine are used for the treatment of demotivation; and bright light used in the early morning to treat SAD. Self-treatments are intended to be used after research and experimentally, on a trial-and-error basis; with self-monitoring of beneficial and harmful

  7. Generalization of the slip line field theory for temperature sensitive visco-plastic materials

    NASA Astrophysics Data System (ADS)

    Paesold, Martin; Peters, Max; Regenauer-Lieb, Klaus; Veveakis, Manolis; Bassom, Andrew

    2015-04-01

    Geological processes can be a combination of various effects such as heat production or consumption, chemical reactions or fluid flow. These individual effects are coupled to each other via feedbacks and the mathematical analysis becomes challenging due to these interdependencies. Here, we concentrate solely on thermo-mechanical coupling and a main result of this work is that the coupling can depend on material parameters and boundary conditions and the coupling is more or less pronounced depending on theses parameters. The transitions from weak to strong coupling can be studied in the context of a bifurcation analysis. classically, Material instabilities in solids are approached as material bifurcations of a rate-independent, isothermal, elasto-plastic solid. However, previous research has shown that temperature and deformation rate are important factors and are fully coupled with the mechanical deformation. Early experiments in steel revealed a distinct pattern of localized heat dissipation and plastic deformation known as heat lines. Further, earth materials, soils, rocks and ceramics are known to be greatly influenced by temperature with strain localization being strongly affected by thermal loading. In this work, we provide a theoretical framework for the evolution of plastic deformation for such coupled systems, with a two-pronged approach to the prediction of localized failure. First, slip line field theory is employed to predict the geometry of the failure patterns and second, failure criteria are derived from an energy bifurcation analysis. The bifurcation analysis is concerned with the local energy balance of a material and compares the effects of heat diffusion terms and heat production terms where the heat production is due to mechanical processes. Commonly, the heat is produced locally along the slip lines and if the heat production outweighs diffusion the material is locally weakened which eventually leads to failure. The effect of diffusion and heat

  8. Cohabitation and Children's Family Instability

    ERIC Educational Resources Information Center

    Kelly Raley, R.; Wildsmith, Elizabeth

    2004-01-01

    This study estimates how much children's family instability is missed when we do not count transitions into and out of cohabitation, and examines early life course trajectories of children to see whether children who experience maternal cohabitation face more family instability than children who do not. Using data from the 1995 National Survey of…

  9. Liquid propellant rocket combustion instability

    NASA Technical Reports Server (NTRS)

    Harrje, D. T.

    1972-01-01

    The solution of problems of combustion instability for more effective communication between the various workers in this field is considered. The extent of combustion instability problems in liquid propellant rocket engines and recommendations for their solution are discussed. The most significant developments, both theoretical and experimental, are presented, with emphasis on fundamental principles and relationships between alternative approaches.

  10. Instability of liquid crystal elastomers

    NASA Astrophysics Data System (ADS)

    An, Ning; Li, Meie; Zhou, Jinxiong

    2016-01-01

    Nematic liquid crystal elastomers (LCEs) contract in the director direction but expand in other directions, perpendicular to the director, when heated. If the expansion of an LCE is constrained, compressive stress builds up in the LCE, and it wrinkles or buckles to release the stored elastic energy. Although the instability of soft materials is ubiquitous, the mechanism and programmable modulation of LCE instability has not yet been fully explored. We describe a finite element method (FEM) scheme to model the inhomogeneous deformation and instability of LCEs. A constrained LCE beam working as a valve for microfluidic flow, and a piece of LCE laminated with a nanoscale poly(styrene) (PS) film are analyzed in detail. The former uses the buckling of the LCE beam to occlude the microfluidic channel, while the latter utilizes wrinkling or buckling to measure the mechanical properties of hard film or to realize self-folding. Through rigorous instability analysis, we predict the critical conditions for the onset of instability, the wavelength and amplitude evolution of instability, and the instability patterns. The FEM results are found to correlate well with analytical results and reported experiments. These efforts shed light on the understanding and exploitation of the instabilities of LCEs.

  11. Research on aviation fuel instability

    NASA Technical Reports Server (NTRS)

    Baker, C. E.; Bittker, D. A.; Cohen, S. M.; Seng, G. T.

    1983-01-01

    The underlying causes of fuel thermal degradation are discussed. Topics covered include: nature of fuel instability and its temperature dependence, methods of measuring the instability, chemical mechanisms involved in deposit formation, and instrumental methods for characterizing fuel deposits. Finally, some preliminary thoughts on design approaches for minimizing the effects of lowered thermal stability are briefly discussed.

  12. Plateau Rayleigh instability simulation.

    PubMed

    Mead-Hunter, Ryan; King, Andrew J C; Mullins, Benjamin J

    2012-05-01

    The well-known phenomena of Plateau-Rayleigh instability has been simulated using computational fluid dynamics (CFD). The breakup of a liquid film into an array of droplets on a cylindrical element was simulated using a volume-of-fluid (VOF) solver and compared to experimental observations and existing theory. It is demonstrated that the VOF method can correctly predict the breakup of thins films into an array of either axisymmetric droplets or clam-shell droplets, depending on the surface energy. The existence of unrealistically large films is precluded. Droplet spacing was found to show reasonable agreement with theory. Droplet motion and displacement under fluid flow was also examined and compared to that in previous studies. It was found that the presence of air flow around the droplet does not influence the stable film thickness; however, it reduces the time required for droplet formation. Novel relationships for droplet displacement were derived from the results. PMID:22512475

  13. Combustion Instabilities Modeled

    NASA Technical Reports Server (NTRS)

    Paxson, Daniel E.

    1999-01-01

    NASA Lewis Research Center's Advanced Controls and Dynamics Technology Branch is investigating active control strategies to mitigate or eliminate the combustion instabilities prevalent in lean-burning, low-emission combustors. These instabilities result from coupling between the heat-release mechanisms of the burning process and the acoustic flow field of the combustor. Control design and implementation require a simulation capability that is both fast and accurate. It must capture the essential physics of the system, yet be as simple as possible. A quasi-one-dimensional, computational fluid dynamics (CFD) based simulation has been developed which may meet these requirements. The Euler equations of mass, momentum, and energy have been used, along with a single reactive species transport equation to simulate coupled thermoacoustic oscillations. A very simple numerical integration scheme was chosen to reduce computing time. Robust boundary condition procedures were incorporated to simulate various flow conditions (e.g., valves, open ends, and choked inflow) as well as to accommodate flow reversals that may arise during large flow-field oscillations. The accompanying figure shows a sample simulation result. A combustor with an open inlet, a choked outlet, and a large constriction approximately two thirds of the way down the length is shown. The middle plot shows normalized, time-averaged distributions of the relevant flow quantities, and the bottom plot illustrates the acoustic mode shape of the resulting thermoacoustic oscillation. For this simulation, the limit cycle peak-to-peak pressure fluctuations were 13 percent of the mean. The simulation used 100 numerical cells. The total normalized simulation time was 50 units (approximately 15 oscillations), which took 26 sec on a Sun Ultra2.

  14. Internal rotor friction instability

    NASA Technical Reports Server (NTRS)

    Walton, J.; Artiles, A.; Lund, J.; Dill, J.; Zorzi, E.

    1990-01-01

    The analytical developments and experimental investigations performed in assessing the effect of internal friction on rotor systems dynamic performance are documented. Analytical component models for axial splines, Curvic splines, and interference fit joints commonly found in modern high speed turbomachinery were developed. Rotor systems operating above a bending critical speed were shown to exhibit unstable subsynchronous vibrations at the first natural frequency. The effect of speed, bearing stiffness, joint stiffness, external damping, torque, and coefficient of friction, was evaluated. Testing included material coefficient of friction evaluations, component joint quantity and form of damping determinations, and rotordynamic stability assessments. Under conditions similar to those in the SSME turbopumps, material interfaces experienced a coefficient of friction of approx. 0.2 for lubricated and 0.8 for unlubricated conditions. The damping observed in the component joints displayed nearly linear behavior with increasing amplitude. Thus, the measured damping, as a function of amplitude, is not represented by either linear or Coulomb friction damper models. Rotordynamic testing of an axial spline joint under 5000 in.-lb of static torque, demonstrated the presence of an extremely severe instability when the rotor was operated above its first flexible natural frequency. The presence of this instability was predicted by nonlinear rotordynamic time-transient analysis using the nonlinear component model developed under this program. Corresponding rotordynamic testing of a shaft with an interference fit joint demonstrated the presence of subsynchronous vibrations at the first natural frequency. While subsynchronous vibrations were observed, they were bounded and significantly lower in amplitude than the synchronous vibrations.

  15. Preserving in Plastic.

    ERIC Educational Resources Information Center

    Wahla, James

    1985-01-01

    Outlines steps for casting insects in permanent molds prepared from commercially available liquid plastic. Also describes dry mountings in glass, acrylic, and petri dishes. The rationale for specimen use, hints for producing quality results, purchasing information, and safety precautions are considered. (DH)

  16. Plastics in Perspective.

    ERIC Educational Resources Information Center

    Bergandine, David R.; Holm, D. Andrew

    The materials in this curriculum supplement, developed for middle school or high school science classes, present solid waste problems related to plastics. The set of curriculum materials is divided into two units to be used together or independently. Unit I begins by comparing patterns in solid waste from 1960 to 1990 and introducing methods for…

  17. Plastics in medical applications.

    PubMed

    Lantos, P R

    1988-01-01

    Plastics are fulfilling a number of critical roles in a variety of medical applications. While some of these are low-technology, throw-away products, many of the applications impose critical requirements as to mechanical performance, chemical resistance, biocompatibility, ability to be sterilized and to remain sterile. By performing capably and reliably in these applications, plastics have found a major outlet, one that offers good opportunities for the present materials as well as for future developments. Numerous challenges remain. The present materials perform, though barely adequately, and superior performance over longer periods of time is an important goal. While off-the-shelf plastics have been used in most medical applications, it is likely that development work will focus on the needs of specific important medical applications. In addition to the usual need for ever decreasing costs and prices, there is the opportunity for materials that possess improved blood compatibility, radiation resistance, and/or in vivo compatibility for improved degradable sutures, coatings for pacemakers, phthalate-free plastics, bags with improved gas impermeability and disposables with controlled degradability. PMID:3230510

  18. Hydrodynamic Elastic Magneto Plastic

    Energy Science and Technology Software Center (ESTSC)

    1985-02-01

    The HEMP code solves the conservation equations of two-dimensional elastic-plastic flow, in plane x-y coordinates or in cylindrical symmetry around the x-axis. Provisions for calculation of fixed boundaries, free surfaces, pistons, and boundary slide planes have been included, along with other special conditions.

  19. Music drives brain plasticity

    PubMed Central

    2009-01-01

    Music is becoming more and more of an issue in the cognitive neurosciences. A major finding in this research area is that musical practice is associated with structural and functional plasticity of the brain. In this brief review, I will give an overview of the most recent findings of this research area. PMID:20948610

  20. Instability-driven electromagnetic fields in coronal plasmasa)

    NASA Astrophysics Data System (ADS)

    Manuel, M. J.-E.; Li, C. K.; Séguin, F. H.; Sinenian, N.; Frenje, J. A.; Casey, D. T.; Petrasso, R. D.; Hager, J. D.; Betti, R.; Hu, S. X.; Delettrez, J.; Meyerhofer, D. D.

    2013-05-01

    Filamentary electromagnetic fields previously observed in the coronae of laser-driven spherical targets [F. H. Séguin et al., Phys. Plasma. 19, 012701 (2012)] have been further investigated in laser-irradiated plastic foils. Face-on proton-radiography provides an axial view of these filaments and shows coherent cellular structure regardless of initial foil-surface conditions. The observed cellular fields are shown to have an approximately constant scale size of ˜210 μm throughout the plasma evolution. A discussion of possible field-generation mechanisms is provided and it is demonstrated that the likely source of the cellular field structure is the magnetothermal instability. Using predicted temperature and density profiles, the fastest growing modes of this instability were found to be slowly varying in time and consistent with the observed cellular size.

  1. Instability-driven electromagnetic fields in coronal plasmas

    DOE PAGESBeta

    Manuel, M. J.-E.; Li, C. K.; Seguin, F. H.; Sinenian, N.; Frenje, J. A.; Casey, D. T.; Petrasso, R. D.; Hager, J. D.; Betti, R.; Hu, S. X.; et al

    2013-04-15

    Filamentary electromagnetic fields previously observed in the coronae of laser-driven spherical targets [F. H. S eguin et al., Phys. Plasma. 19, 012701 (2012)] have been further investigated in laser irradiated plastic foils. Face-on proton-radiography provides an axial view of these filaments and shows coherent cellular structure regardless of initial foil-surface conditions. The observed cellular fields are shown to have an approximately constant scale size of 210 lm throughout the plasma evolution. A discussion of possible field-generation mechanisms is provided and it is demonstrated that the likely source of the cellular field structure is the magnetothermal instability. Using predicted temperature andmore » density profiles, the fastest growing modes of this instability were found to be slowly varying in time and consistent with the observed cellular size.« less

  2. Instability-driven electromagnetic fields in coronal plasmas

    SciTech Connect

    Manuel, M. J.-E.; Li, C. K.; Seguin, F. H.; Sinenian, N.; Frenje, J. A.; Casey, D. T.; Petrasso, R. D.; Hager, J. D.; Betti, R.; Hu, S. X.; Delettrez, J.; Meyerhofer, D. D.

    2013-04-15

    Filamentary electromagnetic fields previously observed in the coronae of laser-driven spherical targets [F. H. S eguin et al., Phys. Plasma. 19, 012701 (2012)] have been further investigated in laser irradiated plastic foils. Face-on proton-radiography provides an axial view of these filaments and shows coherent cellular structure regardless of initial foil-surface conditions. The observed cellular fields are shown to have an approximately constant scale size of 210 lm throughout the plasma evolution. A discussion of possible field-generation mechanisms is provided and it is demonstrated that the likely source of the cellular field structure is the magnetothermal instability. Using predicted temperature and density profiles, the fastest growing modes of this instability were found to be slowly varying in time and consistent with the observed cellular size.

  3. Instability-driven electromagnetic fields in coronal plasmas

    SciTech Connect

    Manuel, M. J.-E.; Li, C. K.; Séguin, F. H.; Sinenian, N.; Frenje, J. A.; Casey, D. T.; Petrasso, R. D.; Hager, J. D.; Betti, R.; Hu, S. X.; Delettrez, J.; Meyerhofer, D. D.

    2013-05-15

    Filamentary electromagnetic fields previously observed in the coronae of laser-driven spherical targets [F. H. Séguin et al., Phys. Plasma. 19, 012701 (2012)] have been further investigated in laser-irradiated plastic foils. Face-on proton-radiography provides an axial view of these filaments and shows coherent cellular structure regardless of initial foil-surface conditions. The observed cellular fields are shown to have an approximately constant scale size of ∼210 μm throughout the plasma evolution. A discussion of possible field-generation mechanisms is provided and it is demonstrated that the likely source of the cellular field structure is the magnetothermal instability. Using predicted temperature and density profiles, the fastest growing modes of this instability were found to be slowly varying in time and consistent with the observed cellular size.

  4. The underestimated impact of instabilities with nanoimprint

    NASA Astrophysics Data System (ADS)

    Mayer, A.; Dhima, K.; Wang, S.; Steinberg, C.; Papenheim, M.; Scheer, H.-C.

    2015-11-01

    With nanoimprint, instabilities of the polymeric layer between the substrate and the stamp are observed when incomplete filling of the stamp cavities prevails, resulting in capillary bridges and meandering structures. Experiments show that instabilities may also affect the initial situation of a thermal nanoimprint process. Already at the beginning of the actual imprint step, the polymeric surface may be highly non-uniform, with undulations of the film thickness, polymeric bridges and de-wetted regions; thus, the starting point for imprint may differ substantially from the general expectation of a uniform spin-coated layer. A detailed instability analysis considering the combined effect of van der Waals forces, electrostatic forces and temperature gradients under realistic imprint conditions clearly identifies temperature gradients to be the cause for high initial layer non-uniformities. We found that during heat-up (before imprint) temperature differences of 10 °C may exist between the top and bottom hotplate of a thermal imprint system. These temperature differences result in the non-uniformities of the polymeric layer observed, when stamp and sample are heated under low-pressure contact, where some small but locally arbitrary gaps exist between polymer and stamp. This result asks for a reconsideration of the thermal nanoimprint procedure. It also confirms the high impact of temperature control for uniform, low-defect imprint results; this is critical not only during imprint, but also during heat-up.

  5. Sawtooth Instability in the Compact Toroidal Hybrid

    NASA Astrophysics Data System (ADS)

    Herfindal, J. L.; Maurer, D. A.; Hartwell, G. J.; Ennis, D. A.; Knowlton, S. F.

    2015-11-01

    Sawtooth instabilities have been observed in the Compact Toroidal Hybrid (CTH), a current-carrying stellarator/tokamak hybrid device. The sawtooth instability is driven by ohmic heating of the core plasma until the safety factor drops below unity resulting in the growth of an m = 1 kink-tearing mode. Experiments varying the vacuum rotational transform from 0.02 to 0.13 are being conducted to study sawtooth property dependance on vacuum flux surface structure. The frequency of the sawtooth oscillations increase from 2 kHz to 2.8 kHz solely due the decrease in rise time of the oscillation, the crash time is unchanged. CTH has three two-color SXR cameras, a three-channel 1mm interferometer, and a new bolometer system capable of detecting the signatures of sawtooth instabilities. The new bolometer system consists of two cameras, each containing a pair of diode arrays viewing the plasma directly or through a beryllium filter. Electron temperature measurements are found with the two-color SXR cameras through a ratio of the SXR intensities. Impurity radiation can drastically affect the electron temperature measurement, therefore new filters consisting of aluminum and carbon were selected to avoid problematic line radiation while maximizing the signal for a 100 eV plasma. This work is supported by U.S. Department of Energy Grant No. DE-FG02-00ER54610.

  6. A Multi-Parameter Approach for Calculating Crack Instability

    NASA Technical Reports Server (NTRS)

    Zanganeh, M.; Forman, R. G.

    2014-01-01

    An accurate fracture control analysis of spacecraft pressure systems, boosters, rocket hardware and other critical low-cycle fatigue cases where the fracture toughness highly impacts cycles to failure requires accurate knowledge of the material fracture toughness. However, applicability of the measured fracture toughness values using standard specimens and transferability of the values to crack instability analysis of the realistically complex structures is refutable. The commonly used single parameter Linear Elastic Fracture Mechanics (LEFM) approach which relies on the key assumption that the fracture toughness is a material property would result in inaccurate crack instability predictions. In the past years extensive studies have been conducted to improve the single parameter (K-controlled) LEFM by introducing parameters accounting for the geometry or in-plane constraint effects]. Despite the importance of the thickness (out-of-plane constraint) effects in fracture control problems, the literature is mainly limited to some empirical equations for scaling the fracture toughness data] and only few theoretically based developments can be found. In aerospace hardware where the structure might have only one life cycle and weight reduction is crucial, reducing the design margin of safety by decreasing the uncertainty involved in fracture toughness evaluations would result in lighter hardware. In such conditions LEFM would not suffice and an elastic-plastic analysis would be vital. Multi-parameter elastic plastic crack tip field quantifying developments combined with statistical methods] have been shown to have the potential to be used as a powerful tool for tackling such problems. However, these approaches have not been comprehensively scrutinized using experimental tests. Therefore, in this paper a multi-parameter elastic-plastic approach has been used to study the crack instability problem and the transferability issue by considering the effects of geometrical

  7. Temperature anisotropy and beam type whistler instabilities

    NASA Technical Reports Server (NTRS)

    Hashimoto, K.; Matsumoto, H.

    1976-01-01

    Whistler instabilities have been investigated for two different types; i.e., a temperature-anisotropy type instability and a beam-type instability. A comparison between the two types of whistler instabilities is made within the framework of linear theory. A transition from one type to the other is also discussed, which is an extension of the work on electrostatic beam and Landau instabilities performed by O'Neil and Malmberg (1968) for electromagnetic whistler instabilities. It is clarified that the essential source of the whistler instability is not beam kinetic energy but a temperature anisotropy, even for the beam-type whistler instability.

  8. Crack Instability Predictions Using a Multi-Term Approach

    NASA Technical Reports Server (NTRS)

    Zanganeh, Mohammad; Forman, Royce G.

    2015-01-01

    Present crack instability analysis for fracture critical flight hardware is normally performed using a single parameter, K(sub C), fracture toughness value obtained from standard ASTM 2D geometry test specimens made from the appropriate material. These specimens do not sufficiently match the boundary conditions and the elastic-plastic constraint characteristics of the hardware component, and also, the crack instability of most commonly used aircraft and aerospace structural materials have some amount of stable crack growth before fracture which makes the normal use of a K(sub C) single parameter toughness value highly approximate. In the past, extensive studies have been conducted to improve the single parameter (K or J controlled) approaches by introducing parameters accounting for the geometry or in-plane constraint effects. Using 'J-integral' and 'A' parameter as a measure of constraint is one of the most accurate elastic-plastic crack solutions currently available. In this work the feasibility of the J-A approach for prediction of the crack instability was investigated first by ignoring the effects of stable crack growth i.e. using a critical J and A and second by considering the effects of stable crack growth using the corrected J-delta a using the 'A' parameter. A broad range of initial crack lengths and a wide range of specimen geometries including C(T), M(T), ESE(T), SE(T), Double Edge Crack (DEC), Three-Hole-Tension (THT) and NC (crack from a notch) manufactured from Al7075 were studied. Improvements in crack instability predictions were observed compared to the other methods available in the literature.

  9. Development of a Practical Methodology for Elastic-Plastic and Fully Plastic Fatigue Crack Growth

    NASA Technical Reports Server (NTRS)

    McClung, R. C.; Chell, G. G.; Lee, Y.-D.; Russell, D. A.; Orient, G. E.

    1999-01-01

    A practical engineering methodology has been developed to analyze and predict fatigue crack growth rates under elastic-plastic and fully plastic conditions. The methodology employs the closure-corrected effective range of the J-integral, (Delta)J(sub eff), as the governing parameter. The methodology contains original and literature J and (Delta)J solutions for specific geometries, along with general methods for estimating J for other geometries and other loading conditions, including combined mechanical loading and combined primary and secondary loading. The methodology also contains specific practical algorithms that translate a J solution into a prediction of fatigue crack growth rate or life, including methods for determining crack opening levels, crack instability conditions, and material properties. A critical core subset of the J solutions and the practical algorithms has been implemented into independent elastic-plastic NASGRO modules. All components of the entire methodology, including the NASGRO modules, have been verified through analysis and experiment, and limits of applicability have been identified.

  10. Development of a Practical Methodology for Elastic-Plastic and Fully Plastic Fatigue Crack Growth

    NASA Technical Reports Server (NTRS)

    McClung, R. C.; Chell, G. G.; Lee, Y. -D.; Russell, D. A.; Orient, G. E.

    1999-01-01

    A practical engineering methodology has been developed to analyze and predict fatigue crack growth rates under elastic-plastic and fully plastic conditions. The methodology employs the closure-corrected effective range of the J-integral, delta J(sub eff) as the governing parameter. The methodology contains original and literature J and delta J solutions for specific geometries, along with general methods for estimating J for other geometries and other loading conditions, including combined mechanical loading and combined primary and secondary loading. The methodology also contains specific practical algorithms that translate a J solution into a prediction of fatigue crack growth rate or life, including methods for determining crack opening levels, crack instability conditions, and material properties. A critical core subset of the J solutions and the practical algorithms has been implemented into independent elastic-plastic NASGRO modules. All components of the entire methodology, including the NASGRO modules, have been verified through analysis and experiment, and limits of applicability have been identified.

  11. Drinking-Straw Microbalance and Seesaw: Stability and Instability

    NASA Astrophysics Data System (ADS)

    Chapman, Peter; Glasser, Leslie

    2015-03-01

    The mechanics of a beam balance are little appreciated and seldom understood. We here consider the conditions that result in a stable balance, with center of gravity below the fulcrum (pivot point), while an unstable balance results when the center of gravity is above the fulcrum. The highly sensitive drinking-straw microbalance, which uses a plastic drinking straw as a rigid beam, is briefly described with some slight convenient modifications. Different placements of the center of gravity are considered analytically to explain the equilibrium neutrality, stability, and instability of such beam balances as the microbalance, the playground "seesaw" or "teeter-totter," the "dipping bird," and other toys and magic tricks.

  12. Hydrodynamic instabilities in beryllium targets for the National Ignition Facility

    NASA Astrophysics Data System (ADS)

    Yi, S. A.; Simakov, A. N.; Wilson, D. C.; Olson, R. E.; Kline, J. L.; Clark, D. S.; Hammel, B. A.; Milovich, J. L.; Salmonson, J. D.; Kozioziemski, B. J.; Batha, S. H.

    2014-09-01

    Beryllium ablators offer higher ablation velocity, rate, and pressure than their carbon-based counterparts, with the potential to increase the probability of achieving ignition at the National Ignition Facility (NIF) [E. I. Moses et al., Phys. Plasmas 16, 041006 (2009)]. We present here a detailed hydrodynamic stability analysis of low (NIF Revision 6.1) and high adiabat NIF beryllium target designs. Our targets are optimized to fully utilize the advantages of beryllium in order to suppress the growth of hydrodynamic instabilities. This results in an implosion that resists breakup of the capsule, and simultaneously minimizes the amount of ablator material mixed into the fuel. We quantify the improvement in stability of beryllium targets relative to plastic ones, and show that a low adiabat beryllium capsule can be at least as stable at the ablation front as a high adiabat plastic target.

  13. Hydrodynamic instabilities in beryllium targets for the National Ignition Facility

    SciTech Connect

    Yi, S. A. Simakov, A. N.; Wilson, D. C.; Olson, R. E.; Kline, J. L.; Batha, S. H.; Clark, D. S.; Hammel, B. A.; Milovich, J. L.; Salmonson, J. D.; Kozioziemski, B. J.

    2014-09-15

    Beryllium ablators offer higher ablation velocity, rate, and pressure than their carbon-based counterparts, with the potential to increase the probability of achieving ignition at the National Ignition Facility (NIF) [E. I. Moses et al., Phys. Plasmas 16, 041006 (2009)]. We present here a detailed hydrodynamic stability analysis of low (NIF Revision 6.1) and high adiabat NIF beryllium target designs. Our targets are optimized to fully utilize the advantages of beryllium in order to suppress the growth of hydrodynamic instabilities. This results in an implosion that resists breakup of the capsule, and simultaneously minimizes the amount of ablator material mixed into the fuel. We quantify the improvement in stability of beryllium targets relative to plastic ones, and show that a low adiabat beryllium capsule can be at least as stable at the ablation front as a high adiabat plastic target.

  14. Plastics for Elementary School Children

    ERIC Educational Resources Information Center

    Hanson, Jack

    1977-01-01

    Describes three plastics projects (which involve making a styrene fishing bobber, an acrylic salad fork and spoon set, and acetate shrink art) designed to provide elementary level students an opportunity to work with plastics and to learn about careers in plastics production and distribution. (TA)

  15. Rigid plastic collars for marking geese

    USGS Publications Warehouse

    Ballou, R.M.; Martin, F.W.

    1964-01-01

    Rigid plastic collars of one to three colors proved useful for recognition of individual Canada geese (Branta canadensis). The collars did not seem to affect the behavior of the geese, and there was little mortality caused by their use. In good light, bright colors are visible through a 20-power spotting scope for more than 1 mile. Retention of collars was about 90 percent for 1 year and more than 80 percent for 2 years.

  16. ROTATIONAL INSTABILITIES AND CENTRIFUGAL HANGUP

    SciTech Connect

    K. NEW; J. CENTRELLA

    2000-12-01

    One interesting class of gravitational radiation sources includes rapidly rotating astrophysical objects that encounter dynamical instabilities. We have carried out a set of simulations of rotationally induced instabilities in differentially rotating polytropes. An n=1.5 polytrope with the Maclaurin rotation law will encounter the m=2 bar instability at T/{vert_bar}W{vert_bar} {ge} 0.27. Our results indicate that the remnant of this in-stability is a persistent bar-like structure that emits a long-lived gravitational radiation signal. Furthermore, dynamical instability is shown to occur in n=3.33 polytropes with the j-constant rotation law at T/{vert_bar}W{vert_bar} {ge} 0:14. In this case, the dominant mode of instability is m=1. Such instability may allow a centrifugally-hung core to begin collapsing to neutron star densities on a dynamical timescale. If it occurs in a supermassive star, it may produce gravitational radiation detectable by LISA.

  17. Transcriptional activation of endothelial cells by TGFβ coincides with acute microvascular plasticity following focal spinal cord ischaemia/reperfusion injury.

    PubMed

    Benton, Richard L; Maddie, Melissa A; Dincman, Toros A; Hagg, Theo; Whittemore, Scott R

    2009-01-01

    Microvascular dysfunction, loss of vascular support, ischaemia and sub-acute vascular instability in surviving blood vessels contribute to secondary injury following SCI (spinal cord injury). Neither the precise temporal profile of the cellular dynamics of spinal microvasculature nor the potential molecular effectors regulating this plasticity are well understood. TGFβ (transforming growth factor β) isoforms have been shown to be rapidly increased in response to SCI and CNS (central nervous system) ischaemia, but no data exist regarding their contribution to microvascular dysfunction following SCI. To examine these issues, in the present study we used a model of focal spinal cord ischaemia/reperfusion SCI to examine the cellular response(s) of affected microvessels from 30 min to 14 days post-ischaemia. Spinal endothelial cells were isolated from affected tissue and subjected to focused microarray analysis of TGFβ-responsive/related mRNAs 6 and 24 h post-SCI. Immunohistochemical analyses of histopathology show neuronal disruption/loss and astroglial regression from spinal microvessels by 3 h post-ischaemia, with complete dissolution of functional endfeet (loss of aquaporin-4) by 12 h post-ischaemia. Coincident with this microvascular plasticity, results from microarray analyses show 9 out of 22 TGFβ-responsive mRNAs significantly up-regulated by 6 h post-ischaemia. Of these, serpine 1/PAI-1 (plasminogen-activator inhibitor 1) demonstrated the greatest increase (>40-fold). Furthermore, uPA (urokinase-type plasminogen activator), another member of the PAS (plasminogen activator system), was also significantly increased (>7.5-fold). These results, along with other select up-regulated mRNAs, were confirmed biochemically or immunohistochemically. Taken together, these results implicate TGFβ as a potential molecular effector of the anatomical and functional plasticity of microvessels following SCI. PMID:19663807

  18. Transcriptional activation of endothelial cells by TGFβ coincides with acute microvascular plasticity following focal spinal cord ischaemia/reperfusion injury

    PubMed Central

    Benton, Richard L; Maddie, Melissa A; Dincman, Toros A; Hagg, Theo; Whittemore, Scott R

    2009-01-01

    Microvascular dysfunction, loss of vascular support, ischaemia and sub-acute vascular instability in surviving blood vessels contribute to secondary injury following SCI (spinal cord injury). Neither the precise temporal profile of the cellular dynamics of spinal microvasculature nor the potential molecular effectors regulating this plasticity are well understood. TGFβ (transforming growth factor β) isoforms have been shown to be rapidly increased in response to SCI and CNS (central nervous system) ischaemia, but no data exist regarding their contribution to microvascular dysfunction following SCI. To examine these issues, in the present study we used a model of focal spinal cord ischaemia/reperfusion SCI to examine the cellular response(s) of affected microvessels from 30 min to 14 days post-ischaemia. Spinal endothelial cells were isolated from affected tissue and subjected to focused microarray analysis of TGFβ-responsive/related mRNAs 6 and 24 h post-SCI. Immunohistochemical analyses of histopathology show neuronal disruption/loss and astroglial regression from spinal microvessels by 3 h post-ischaemia, with complete dissolution of functional endfeet (loss of aquaporin-4) by 12 h post-ischaemia. Coincident with this microvascular plasticity, results from microarray analyses show 9 out of 22 TGFβ-responsive mRNAs significantly up-regulated by 6 h post-ischaemia. Of these, serpine 1/PAI-1 (plasminogen-activator inhibitor 1) demonstrated the greatest increase (>40-fold). Furthermore, uPA (urokinase-type plasminogen activator), another member of the PAS (plasminogen activator system), was also significantly increased (>7.5-fold). These results, along with other select up-regulated mRNAs, were confirmed biochemically or immunohistochemically. Taken together, these results implicate TGFβ as a potential molecular effector of the anatomical and functional plasticity of microvessels following SCI. PMID:19663807

  19. Compressibility effect on magnetic-shear-localized ideal magnetohydrodynamic interchange instability

    SciTech Connect

    Gupta, Sangeeta; Callen, J.D.; Hegna, C.C.

    2005-08-15

    Eigenmode analysis of a magnetic-shear-localized ideal magnetohydrodynamic interchange instability in the presence of plasma compressibility indicates the marginal stability criterion (D{sub I}=1/4) is not affected by the compressibility effects. Above the marginal stability criterion, plasma compressibility causes a significant reduction in the growth rate of an ideal interchange instability.

  20. New instability of Saturn's ring

    SciTech Connect

    Goertz, C.K.; Morfill, G.

    1988-05-01

    Perturbations in the Saturn ring's mass density are noted to be prone to instabilities through the sporadic elevation of submicron-size dust particles above the rings, which furnishes an effective angular momentum exchange between the rings and Saturn. The dust thus elevated from the ring settles back onto it at a different radial distance. The range of wavelength instability is determinable in light of the dust charge, the average radial displacement of the dust, and the fluctuation of these quantities. It is suggested that at least some of the B-ring's ringlets may arise from the instability.

  1. Microbunching Instability in Velocity Bunching

    SciTech Connect

    Xiang, D; Wu, J.; /SLAC

    2009-05-26

    Microbunching instability is one of the most challenging threats to FEL performances. The most effective ways to cure the microbunching instability include suppression of the density modulation sources and suppression of the amplification process. In this paper we study the microbunching instability in velocity bunching. Our simulations show that the initial current and energy modulations are suppressed in velocity bunching process, which may be attributed to the strong plasma oscillation and Landau damping from the relatively low beam energy and large relative slice energy spread. A heating effect that may be present in a long solenoid is also preliminarily analyzed.

  2. Shock-induced crystalline instabilities

    NASA Astrophysics Data System (ADS)

    Ravelo, Ramon; Holian, Brad Lee; Germann, Timothy C.

    2007-03-01

    Uniaxial deformations of single crystals such as those produced under planar shock loading can produce structural instabilities which compete with defect nucleation mechanisms. In fcc single crystals under (110) shock loading, the resulting body-centered orthorhombic crystal structure develops a long-wavelength dynamical instability associated with tetragonal shear distortions, which occurs at lower strains (pressures) than those predicted by the vanishing of the elastic constants at finite pressure (stiffness coefficients). The criterion for these instabilities is derived and verified by equilibrium and non-equilibrium molecular dynamics simulations [2]J. Wang, S. Yip, S.R. Phillpot, D. Wolf, Phys. Rev. Lett. 71, 4182 (1993)

  3. Origins of Folding Instabilities on Polycrystalline Metal Surfaces

    NASA Astrophysics Data System (ADS)

    Beckmann, N.; Romero, P. A.; Linsler, D.; Dienwiebel, M.; Stolz, U.; Moseler, M.; Gumbsch, P.

    2014-12-01

    Wear and removal of material from polycrystalline metal surfaces is inherently connected to plastic flow. Here, plowing-induced unconstrained surface plastic flow on a nanocrystalline copper surface has been studied by massive molecular dynamics simulations and atomic force microscopy scratch experiments. In agreement with experimental findings, bulges in front of a model asperity develop into vortexlike fold patterns that mark the disruption of laminar flow. We identify dislocation-mediated plastic flow in grains with suitably oriented slip systems as the basic mechanism of bulging and fold formation. The observed folding can be fundamentally explained by the inhomogeneity of plasticity on polycrystalline surfaces which favors bulge formation on grains with suitably oriented slip system. This process is clearly distinct from Kelvin-Helmholtz instabilities in fluids, which have been previously suggested to resemble the formed surface fold patterns. The generated prow grows into a rough chip with stratified lamellae that are identified as the precursors of wear debris. Our findings demonstrate the importance of surface texture and grain structure engineering to achieve ultralow wear in metals.

  4. [Cancer cell plasticity and metastatic dissemination].

    PubMed

    Moyret-Lalle, Caroline; Pommier, Roxane; Bouard, Charlotte; Nouri, Ebticem; Richard, Geoffrey; Puisieux, Alain

    Metastatic dissemination consists of a sequence of events resulting in the invasion by cancer cells of tissues located away from the primary tumour. This process is highly inefficient, since each event represents an obstacle that only a limited number of cells can overcome. However, two biological phenomena intrinsically linked with tumour development facilitate the dissemination of cancer cells throughout the body and promote the formation of metastases, namely the genetic diversity of cancer cells within a given tumour, which arises from their genetic instability and from successive clonal expansions, and cellular plasticity conveyed to the cells by micro-environmental signals. Genetic diversity increases the probability of selecting cells that are intrinsically resistant to biological and physical constraints encountered during metastatic dissemination, whereas cellular plasticity provides cells with the capacity to adapt to stressful conditions and to changes in the microenvironment. The epithelial-mesenchymal transition, an embryonic trans-differentiation process frequently reactivated during tumour development, plays an important role in that context by endowing tumor cells with a unique capacity of motility, survival and adaptability to the novel environments and stresses encountered during the invasion-metastasis cascade. PMID:27615180

  5. Evidence of selection on phenotypic plasticity and cost of plasticity in response to host-feeding sources in the major Chagas disease vector Triatoma infestans.

    PubMed

    Nattero, Julieta; Leonhard, Gustavo; Gürtler, Ricardo E; Crocco, Liliana B

    2015-12-01

    Phenotypic plasticity is the ability of a genotype to display alternative phenotypes in different environments. Understanding how plasticity evolves and the factors that favor and constrain its evolution have attracted great interest. We investigated whether selection on phenotypic plasticity and costs of plasticity affect head and wing morphology in response to host-feeding sources in the major Chagas disease vector Triatoma infestans. Full-sib families were assigned to blood-feeding on either live pigeons or guinea pigs throughout their lives. We measured diet-induced phenotypic plasticity on wing and head size and shape; characterized selection on phenotypic plasticity for female and male fecundity rates, and evaluated costs of plasticity. Wing size and shape variables exhibited significant differences in phenotypic plasticity associated with host-feeding source in female and male bugs. Evidence of selection on phenotypic plasticity was detected in head size and shape for guinea pig-fed females. A lower female fecundity rate was detected in more plastic families for traits that showed selection on plasticity. These results provide insights into the morphological phenotypic plasticity of T. infestans, documenting fitness advantages of head size and shape for females fed on guinea pigs. This vector species showed measurable benefits of responding plastically to environmental variation rather than adopting a fixed development plan. The presence of cost of plasticity suggests constraints on the evolution of plasticity. Our study indicates that females fed on guinea pigs (and perhaps on other suitable mammalian hosts) have greater chances of evolving under selection on phenotypic plasticity subject to some constraints. PMID:26433077

  6. 49 CFR 192.619 - Maximum allowable operating pressure: Steel or plastic pipelines.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...: For Federal Register citations affecting § 192.619, see the List of CFR Sections Affected, which... plastic pipelines. 192.619 Section 192.619 Transportation Other Regulations Relating to Transportation... Operations § 192.619 Maximum allowable operating pressure: Steel or plastic pipelines. (a) No person...

  7. 49 CFR 192.619 - Maximum allowable operating pressure: Steel or plastic pipelines.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...: For Federal Register citations affecting § 192.619, see the List of CFR Sections Affected, which... plastic pipelines. 192.619 Section 192.619 Transportation Other Regulations Relating to Transportation... Operations § 192.619 Maximum allowable operating pressure: Steel or plastic pipelines. (a) No person...

  8. 49 CFR 192.619 - Maximum allowable operating pressure: Steel or plastic pipelines.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...: For Federal Register citations affecting § 192.619, see the List of CFR Sections Affected, which... plastic pipelines. 192.619 Section 192.619 Transportation Other Regulations Relating to Transportation... Operations § 192.619 Maximum allowable operating pressure: Steel or plastic pipelines. (a) No person...

  9. 49 CFR 192.619 - Maximum allowable operating pressure: Steel or plastic pipelines.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...: For Federal Register citations affecting § 192.619, see the List of CFR Sections Affected, which... plastic pipelines. 192.619 Section 192.619 Transportation Other Regulations Relating to Transportation... Operations § 192.619 Maximum allowable operating pressure: Steel or plastic pipelines. (a) No person...

  10. 49 CFR 192.619 - Maximum allowable operating pressure: Steel or plastic pipelines.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...: For Federal Register citations affecting § 192.619, see the List of CFR Sections Affected, which... plastic pipelines. 192.619 Section 192.619 Transportation Other Regulations Relating to Transportation... Operations § 192.619 Maximum allowable operating pressure: Steel or plastic pipelines. (a) No person...

  11. [Motor Proteins of Microtubules and Mechanisms of Synaptic Plasticity].

    PubMed

    Vasilyeva, N A; Pivovarov, A S

    2016-01-01

    Motor proteins of microtubules, kinesin and dynein superfamily proteins play an important role in the intracellular transport. Inside a neuron they are involved in the transport of organelles, proteins and mRNAs along the axons and dendrites to the nerve terminals and back to the cell bodies. Disturbance of axonal transport may affect neurotransmitter release and short-term presynaptic plasticity. Disturbance of dendritic transport, in particular the recycling of synaptic receptors, affects postsynaptic plasticity. The review attempts to trace the connections between the motor proteins of microtubules and mechanisms of synaptic plasticity from the perspective of their involvement in the intracellular transport of proteins and organelles, which play role in the mechanisms of synaptic plasticity. PMID:27538280

  12. Breathing: Rhythmicity, Plasticity, Chemosensitivity

    PubMed Central

    Feldman, Jack L.; Mitchell, Gordon S.; Nattie, Eugene E.

    2010-01-01

    Breathing is a vital behavior that is particularly amenable to experimental investigation. We review recent progress on three problems of broad interest. (i) Where and how is respiratory rhythm generated? The preBötzinger Complex is a critical site, whereas pacemaker neurons may not be essential. The possibility that coupled oscillators are involved is considered. (ii) What are the mechanisms that underlie the plasticity necessary for adaptive changes in breathing? Serotonin-dependent long-term facilitation following intermittent hypoxia is an important example of such plasticity, and a model that can account for this adaptive behavior is discussed. (iii) Where and how are the regulated variables CO2 and pH sensed? These sensors are essential if breathing is to be appropriate for metabolism. Neurons with appropriate chemosensitivity are spread throughout the brainstem; their individual properties and collective role are just beginning to be understood. PMID:12598679

  13. Resistive instabilities in tokamaks

    SciTech Connect

    Rutherford, P.H.

    1985-10-01

    Low-m tearing modes constitute the dominant instability problem in present-day tokamaks. In this lecture, the stability criteria for representative current profiles with q(0)-values slightly less than unit are reviewed; ''sawtooth'' reconnection to q(0)-values just at, or slightly exceeding, unity is generally destabilizing to the m = 2, n = 1 and m = 3, n = 2 modes, and severely limits the range of stable profile shapes. Feedback stabilization of m greater than or equal to 2 modes by rf heating or current drive, applied locally at the magnetic islands, appears feasible; feedback by island current drive is much more efficient, in terms of the radio-frequency power required, then feedback by island heating. Feedback stabilization of the m = 1 mode - although yielding particularly beneficial effects for resistive-tearing and high-beta stability by allowing q(0)-values substantially below unity - is more problematical, unless the m = 1 ideal-MHD mode can be made positively stable by strong triangular shaping of the central flux surfaces. Feedback techniques require a detectable, rotating MHD-like signal; the slowing of mode rotation - or the excitation of non-rotating modes - by an imperfectly conducting wall is also discussed.

  14. Sheared Electroconvective Instability

    NASA Astrophysics Data System (ADS)

    Kwak, Rhokyun; Pham, Van Sang; Lim, Kiang Meng; Han, Jongyoon

    2012-11-01

    Recently, ion concentration polarization (ICP) and related phenomena draw attention from physicists, due to its importance in understanding electrochemical systems. Researchers have been actively studying, but the complexity of this multiscale, multiphysics phenomenon has been limitation for gaining a detailed picture. Here, we consider electroconvective(EC) instability initiated by ICP under pressure-driven flow, a scenario often found in electrochemical desalinations. Combining scaling analysis, experiment, and numerical modeling, we reveal unique behaviors of sheared EC: unidirectional vortex structures, its size selection and vortex propagation. Selected by balancing the external pressure gradient and the electric body force, which generates Hagen-Poiseuille(HP) flow and vortical EC, the dimensionless EC thickness scales as (φ2 /UHP)1/3. The pressure-driven flow(or shear) suppresses unfavorably-directed vortices, and simultaneously pushes favorably-directed vortices with constant speed, which is linearly proportional to the total shear of HP flow. This is the first systematic characterization of sheared EC, which has significant implications on the optimization of electrodialysis and other electrochemical systems.

  15. Instabilities in the aether

    SciTech Connect

    Carroll, Sean M.; Dulaney, Timothy R.; Gresham, Moira I.; Tam, Heywood

    2009-03-15

    We investigate the stability of theories in which Lorentz invariance is spontaneously broken by fixed-norm vector 'aether' fields. Models with generic kinetic terms are plagued either by ghosts or by tachyons, and are therefore physically unacceptable. There are precisely three kinetic terms that are not manifestly unstable: a sigma model ({partial_derivative}{sub {mu}}A{sub {nu}}){sup 2}, the Maxwell Lagrangian F{sub {mu}}{sub {nu}}F{sup {mu}}{sup {nu}}, and a scalar Lagrangian ({partial_derivative}{sub {mu}}A{sup {mu}}){sup 2}. The timelike sigma-model case is well defined and stable when the vector norm is fixed by a constraint; however, when it is determined by minimizing a potential there is necessarily a tachyonic ghost, and therefore an instability. In the Maxwell and scalar cases, the Hamiltonian is unbounded below, but at the level of perturbation theory there are fewer degrees of freedom and the models are stable. However, in these two theories there are obstacles to smooth evolution for certain choices of initial data.

  16. Bipolar disorder dynamics: affective instabilities, relaxation oscillations and noise

    PubMed Central

    Geddes, John R.; Goodwin, Guy M.; Holmes, Emily A.

    2015-01-01

    Bipolar disorder is a chronic, recurrent mental illness characterized by extreme episodes of depressed and manic mood, interspersed with less severe but highly variable mood fluctuations. Here, we develop a novel mathematical approach for exploring the dynamics of bipolar disorder. We investigate how the dynamics of subjective experience of mood in bipolar disorder can be understood using a relaxation oscillator (RO) framework and test the model against mood time-series fluctuations from a set of individuals with bipolar disorder. We show that variable mood fluctuations in individuals diagnosed with bipolar disorder can be driven by the coupled effects of deterministic dynamics (captured by ROs) and noise. Using a statistical likelihood-based approach, we show that, in general, mood dynamics are described by two independent ROs with differing levels of endogenous variability among individuals. We suggest that this sort of nonlinear approach to bipolar disorder has neurobiological, cognitive and clinical implications for understanding this mental illness through a mechacognitive framework. PMID:26577592

  17. Phenotypic Plasticity and Selection: Nonexclusive Mechanisms of Adaptation

    PubMed Central

    Grenier, S.; Barre, P.; Litrico, I.

    2016-01-01

    Selection and plasticity are two mechanisms that allow the adaptation of a population to a changing environment. Interaction between these nonexclusive mechanisms must be considered if we are to understand population survival. This review discusses the ways in which plasticity and selection can interact, based on a review of the literature on selection and phenotypic plasticity in the evolution of populations. The link between selection and phenotypic plasticity is analysed at the level of the individual. Plasticity can affect an individual's response to selection and so may modify the end result of genetic diversity evolution at population level. Genetic diversity increases the ability of populations or communities to adapt to new environmental conditions. Adaptive plasticity increases individual fitness. However this effect must be viewed from the perspective of the costs of plasticity, although these are not easy to estimate. It is becoming necessary to engage in new experimental research to demonstrate the combined effects of selection and plasticity for adaptation and their consequences on the evolution of genetic diversity. PMID:27313957

  18. Plasticity Effects in Dynamically Loaded Nickel Aluminide Bicrystals

    SciTech Connect

    Loomis, E; Swift, D; McNaney, J; Lorenzana, H; Peralta, P

    2008-12-02

    Elastic and plastic anisotropy are believed to play large roles in the dynamic deformation of many materials at the grain-level. More importantly to polycrystalline materials is how velocity and stress perturbations are transmitted across interfaces in anisotropic materials. Very little work has been done in this area even though it is important for understanding shock/grain boundary interactions. Therefore, experiments have been performed using nanosecond laser shocks of grown Nickel Aluminide bicrystals at tens of GPa. Velocity histories were measured along a line on the back (free) surface of the bicrystals and used to characterize the material behavior. Unstable plastic flow in <100> grains was seen to occur when loaded above 700 m/s free surface velocity. Flow stresses in <111> and <100> grains were measured to be 2.9 and 3.3 GPa, respectively. Calculations were performed based on anisotropic elasticity and dislocation motion on primary slip systems to measure plastic flow properties where plastic strain-rates on the order of 10{sup 6} s{sup -1} were calculated using the experimental velocity histories. Definitive evidence of plastic wave scattering at the grain boundary was not observed experimentally; however, behavior across the grain boundary has been measured. The observations show that a smooth transition occurs between the elastic precursors in both grains as well as the plastic waves (when plastic flow is evident). An anisotropic elastic-plastic wave scattering model has been developed to explain the mechanisms affecting shock/grain boundary interactions.

  19. Maximizing the life cycle of plastics. Final report

    SciTech Connect

    Hawkins, W. L.

    1980-02-01

    The Plastics Research Institute has conducted a coordinated research program designed to extend the useful life of plastics. Since feedstock for practically all synthetic plastics is derived from fossil fuel, every effort should be made to obtain the maximum useful life from these materials. Eventually, plastic scrap may be used as a fuel supplement, but this disposal route should be followed only after the scrap is no longer reusable in its polymeric form. The extent to which plastic scrap will be recovered and reused will be affected by the economic situation as well as the available supply of fossil fuel. The Institute's program was conducted at five major universities. Dedicated faculty members were assembled into a research team and met frequently with members of the Institute's Board of Trustees to review progress of the program. The research was conducted by graduate students in partial fulfillment of degree requirements. Summaries are presented of the following research projects: Improved Stabilization; Separation of Mixed Plastic Scrap; Compatibilizing Agents for Mixed Plastic Scrap; Controlled Degradation of Plastic Scrap; and Determination of Compatibility.

  20. 77 FR 54930 - Carlyle Plastics and Resins, Formerly Known as Fortis Plastics, A Subsidiary of Plastics...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... determination was published in the Federal Register on Monday, July 23, 2012 (77 FR 43123). ] At the request of... Employment and Training Administration Carlyle Plastics and Resins, Formerly Known as Fortis Plastics, A Subsidiary of Plastics Acquisitions Inc., Including On-Site Leased Workers From Kelly Services and...

  1. Frozen cultural plasticity.

    PubMed

    Houdek, Petr; Novakova, Julie

    2016-01-01

    We discuss cultural group selection under the view of the frozen plasticity theory and the different explanatory power and predictions of this framework. We present evidence that cultural adaptations and their influence on the degree of cooperation may be more complex than presented by Richerson et al., and conclude with the gene-environment-culture relationship and its impacts on cultural group selection. PMID:27561647

  2. Compensatory plasticity: time matters

    PubMed Central

    Lazzouni, Latifa; Lepore, Franco

    2014-01-01

    Plasticity in the human and animal brain is the rule, the base for development, and the way to deal effectively with the environment for making the most efficient use of all the senses. When the brain is deprived of one sensory modality, plasticity becomes compensatory: the exception that invalidates the general loss hypothesis giving the opportunity of effective change. Sensory deprivation comes with massive alterations in brain structure and function, behavioral outcomes, and neural interactions. Blind individuals do as good as the sighted and even more, show superior abilities in auditory, tactile and olfactory processing. This behavioral enhancement is accompanied with changes in occipital cortex function, where visual areas at different levels become responsive to non-visual information. The intact senses are in general used more efficiently in the blind but are also used more exclusively. New findings are disentangling these two aspects of compensatory plasticity. What is due to visual deprivation and what is dependent on the extended use of spared modalities? The latter seems to contribute highly to compensatory changes in the congenitally blind. Short-term deprivation through the use of blindfolds shows that cortical excitability of the visual cortex is likely to show rapid modulatory changes after few minutes of light deprivation and therefore changes are possible in adulthood. However, reorganization remains more pronounced in the congenitally blind. Cortico-cortical pathways between visual areas and the areas of preserved sensory modalities are inhibited in the presence of vision, but are unmasked after loss of vision or blindfolding as a mechanism likely to drive cross-modal information to the deafferented visual cortex. The development of specialized higher order visual pathways independently from early sensory experience is likely to preserve their function and switch to the intact modalities. Plasticity in the blind is also accompanied with

  3. Observation of transverse instabilities in the FNAL 200 MeV Linac

    SciTech Connect

    McCrory, E.; Lee, G.; Webber, R.C.

    1988-10-01

    Using newly installed Beam Position Monitors in the downstream half of the FNAL Linac, we have observed significant transverse beam instabilities within the 30 ..mu..s beam pulse. We can affect the instability so that the peak-to-peak amplitude is as small as 0.5 mm or as large as 8 mm. The effect is largely due to a beam-plasma instability in the ten-meter 750-keV transport line. Other causes are being investigated. Using these instabilities as an analysis tool, the betatron amplitude of the beam has been reduced. 7 refs., 4 figs.

  4. Topographically generated internal waves and boundary layer instabilities

    NASA Astrophysics Data System (ADS)

    Soontiens, Nancy; Stastna, Marek; Waite, Michael L.

    2015-08-01

    Flow over topography has been shown to generate finite amplitude internal waves upstream, over the topography and downstream. Such waves can interact with the viscous bottom boundary layer to produce vigorous instabilities. However, the strength and size of such instabilities depends on whether viscosity significantly modifies the wave generation process, which is usually treated using inviscid theory in the literature. In this work, we contrast cases in which boundary layer separation profoundly alters the wave generation process and cases for which the generated internal waves largely match inviscid theory. All results are generated using a numerical model that simulates stratified flow over topography. Several issues with using a wave-based Reynolds number to describe boundary layer properties are discussed by comparing simulations with modifications to the domain depth, background velocity, and viscosity. For hill-like topography, three-dimensional aspects of the instabilities are also discussed. Decreasing the Reynolds number by a factor of four (by increasing the viscosity), while leaving the primary two-dimensional instabilities largely unchanged, drastically affects their three-dimensionalization. Several cases at the laboratory scale with a depth of 1 m are examined in both two and three dimensions and a subset of the cases is scaled up to a field scale 10-m deep fluid while maintaining similar values for the background current and viscosity. At this scale, increasing the viscosity by an order of magnitude does not significantly change the wave properties but does alter the wave's interaction with the bottom boundary layer through the bottom shear stress. Finally, two subcritical cases for which disturbances are able to propagate upstream showcase a set of instabilities forming on the upstream slope of the elevated topography. The time scale over which these instabilities develop is related to but distinct from the advective time scale of the waves. At a

  5. Plastic ingestion by harbour seals (Phoca vitulina) in The Netherlands.

    PubMed

    Bravo Rebolledo, Elisa L; Van Franeker, Jan A; Jansen, Okka E; Brasseur, Sophie M J M

    2013-02-15

    Abundance of ingested debris by seals has been mentioned as a potential indicator of marine litter in the European Marine Strategy Framework Directive (MSFD). A sample of 107 stomachs, 100 intestines and 125 scats of harbour seals from the Netherlands was analysed for the presence of plastics. Incidence of plastic was 11% for stomachs, 1% for intestines, and 0% for scats. Younger animals, up to 3 years of age, were most affected. This is the first quantitative study of plastic ingestion by phocid seals. The observed level of incidence is of environmental concern, but is low in the sense of suitability of seals for MSFD monitoring purposes. PMID:23245459

  6. Plastic footwear for leprosy.

    PubMed

    Antia, N H

    1990-03-01

    The anaesthetic foot in leprosy poses the most major problem in the rehabilitation of its patients. Various attempts have been made to produce protective footwear such as the microcellular rubber-car-tyre sandals. Unfortunately these attempts have had little success on a large scale because of the inability to produce them in large numbers and the stigma attached to such unusual footwear. While such footwear may be superior to the 'tennis' shoe in protecting the foot from injury by the penetration of sharp objects, it fails to distribute the weight-bearing forces which is the major cause of plantar damage and ulceration in the anaesthetic foot. This can be achieved by providing rigidity to the sole, as demonstrated by the healing of ulcers in plaster of paris casts or the rigid wooden clog. A new type of moulded plastic footwear has been evolved in conjunction with the plastic footwear industry which provides footwear that can be mass produced at a low price and which overcomes the stigma of leprosy. Controlled rigidity is provided by the incorporation of a spring steel shank between the sponge insole and the hard wearing plastic sole. Trials have demonstrated both the acceptability of the footwear and its protective effects as well as its hard wearing properties. PMID:2319903

  7. Plasticity of amyloid fibrils†

    PubMed Central

    Wetzel, Ronald; Shivaprasad, Shankaramma; Williams, Angela D.

    2008-01-01

    In experiments designed to characterize the basis of amyloid fibril stability through mutational analysis of the Aβ(1-40) molecule, fibrils exhibit consistent, significant structural malleability. In these results, and in other properties, amyloid fibrils appear to more resemble plastic materials generated from synthetic polymers than they do globular proteins. Thus, like synthetic polymers and plastics, amyloid fibrils exhibit both polymorphism, the ability of one polypeptide to form aggregates of different morphologies, and isomorphism, the ability of different polypeptides to grow into a fibrillar amyloid morphology. This view links amyloid with the prehistorical and 20th Century use of proteins as starting materials to make films, fibers, and plastics, and with the classic protein fiber stretching experiments of the Astbury group. Viewing amyloid from the point of view of the polymer chemist may shed new light on issues such as the role of protofibrils in the mechanism of amyloid formation, the biological potency of fibrils, and the prospects for discovering inhibitors of amyloid fibril formation. PMID:17198370

  8. Respiratory Muscle Plasticity

    PubMed Central

    Gransee, Heather M.; Mantilla, Carlos B.; Sieck, Gary C.

    2014-01-01

    Muscle plasticity is defined as the ability of a given muscle to alter its structural and functional properties in accordance with the environmental conditions imposed on it. As such, respiratory muscle is in a constant state of remodeling, and the basis of muscle’s plasticity is its ability to change protein expression and resultant protein balance in response to varying environmental conditions. Here, we will describe the changes of respiratory muscle imposed by extrinsic changes in mechanical load, activity, and innervation. Although there is a large body of literature on the structural and functional plasticity of respiratory muscles, we are only beginning to understand the molecular-scale protein changes that contribute to protein balance. We will give an overview of key mechanisms regulating protein synthesis and protein degradation, as well as the complex interactions between them. We suggest future application of a systems biology approach that would develop a mathematical model of protein balance and greatly improve treatments in a variety of clinical settings related to maintaining both muscle mass and optimal contractile function of respiratory muscles. PMID:23798306

  9. Microelectronics plastic molded packaging

    SciTech Connect

    Johnson, D.R.; Palmer, D.W.; Peterson, D.W.

    1997-02-01

    The use of commercial off-the-shelf (COTS) microelectronics for nuclear weapon applications will soon be reality rather than hearsay. The use of COTS for new technologies for uniquely military applications is being driven by the so-called Perry Initiative that requires the U.S. Department of Defense (DoD) to accept and utilize commercial standards for procurement of military systems. Based on this philosophy, coupled with several practical considerations, new weapons systems as well as future upgrades will contain plastic encapsulated microelectronics. However, a conservative Department of Energy (DOE) approach requires lifetime predictive models. Thus, the focus of the current project is on accelerated testing to advance current aging models as well as on the development of the methodology to be used during WR qualification of plastic encapsulated microelectronics. An additional focal point involves achieving awareness of commercial capabilities, materials, and processes. One of the major outcomes of the project has been the definition of proper techniques for handling and evaluation of modern surface mount parts which might be used in future systems. This program is also raising the familiarity level of plastic within the weapons complex, allowing subsystem design rules accommodating COTS to evolve. A two year program plan is presented along with test results and commercial interactions during this first year.

  10. KVP meter errors induced by plastic wrap

    SciTech Connect

    Jefferies, D.; Morris, J.W.; White, V.P. )

    1991-02-01

    The purpose of this study was to determine whether erroneous kVp meter readings, induced by plastic wrap, affected the actual kVp (output) of a dental X-ray machine. To evaluate the effect of plastic wrap on dental X-ray machine kVp meters, a radiation output device was used to measure output in mR/ma.s. An intraoral dental X-ray unit (S.S. White Model {number sign}90W) was used to make the exposures. First, the kVp meter was not covered with plastic wrap and output readings were recorded at various kVp settings with the milliamperage and time held constant. Secondly, the same kVp settings were selected before the plastic wrap was placed. Milliamperage and time were again held to the same constant. The X-ray console was then covered with plastic wrap prior to measuring the output for each kVp. The wrap possessed a static charge. This charge induced erroneous kVp meter readings. Out-put readings at the various induced kVp settings were then recorded. A kVp of 50 with no wrap present resulted in the same output as a kVp of 50 induced to read 40 or 60 kVp by the presence of wrap. Similar results were obtained at other kVp settings. This indicates that the plastic wrap influences only the kVp meter needle and not the actual kilovoltage of the X-ray machine. Dental X-ray machine operators should select kVp meter readings prior to placing plastic wrap and should not adjust initial settings if the meter is deflected later by the presence of wrap. The use of such a procedure will result in proper exposures, fewer retakes, and less patient radiation. If plastic wrap leads to consistent exposure errors, clinicians may wish to use a 0.5% sodium hypochlorite disinfectant as an alternative to the barrier technique.

  11. New perspectives in plastic biodegradation.

    PubMed

    Sivan, Alex

    2011-06-01

    During the past 50 years new plastic materials, in various applications, have gradually replaced the traditional metal, wood, leather materials. Ironically, the most preferred property of plastics--durability--exerts also the major environmental threat. Recycling has practically failed to provide a safe solution for disposal of plastic waste (only 5% out of 1 trillion plastic bags, annually produced in the US alone, are being recycled). Since the most utilized plastic is polyethylene (PE; ca. 140 million tons/year), any reduction in the accumulation of PE waste alone would have a major impact on the overall reduction of the plastic waste in the environment. Since PE is considered to be practically inert, efforts were made to isolate unique microorganisms capable of utilizing synthetic polymers. Recent data showed that biodegradation of plastic waste with selected microbial strains became a viable solution. PMID:21356588

  12. Development, maternal effects, and behavioral plasticity.

    PubMed

    Mateo, Jill M

    2014-11-01

    Behavioral, hormonal, and genetic processes interact reciprocally, and differentially affect behavior depending on ecological and social contexts. When individual differences are favored either between or within environments, developmental plasticity would be expected. Parental effects provide a rich source for phenotypic plasticity, including anatomical, physiological, and behavioral traits, because parents respond to dynamic cues in their environment and can, in turn, influence offspring accordingly. Because these inter-generational changes are plastic, parents can respond rapidly to changing environments and produce offspring whose phenotypes are well suited for current conditions more quickly than occurs with changes based on evolution through natural selection. I review studies on developmental plasticity and resulting phenotypes in Belding's ground squirrels (Urocitellus beldingi), an ideal species, given the competing demands to avoid predation while gaining sufficient weight to survive an upcoming hibernation, and the need for young to learn their survival behaviors. I will show how local environments and perceived risk of predation influence not only foraging, vigilance, and anti-predator behaviors, but also adrenal functioning, which may be especially important for obligate hibernators that face competing demands on the storage and mobilization of glucose. Mammalian behavioral development is sensitive to the social and physical environments provided by mothers during gestation and lactation. Therefore, maternal effects on offspring's phenotypes, both positive and negative, can be particularly strong. PMID:24820855

  13. Ocean acidification challenges copepod reproductive plasticity

    NASA Astrophysics Data System (ADS)

    Vehmaa, A.; Almén, A.-K.; Brutemark, A.; Paul, A.; Riebesell, U.; Furuhagen, S.; Engström-Öst, J.

    2015-11-01

    Ocean acidification is challenging phenotypic plasticity of individuals and populations. Calanoid copepods (zooplankton) are shown to be fairly plastic against altered pH conditions, and laboratory studies indicate that transgenerational effects are one mechanism behind this plasticity. We studied phenotypic plasticity of the copepod Acartia bifilosa in the course of a pelagic, large-volume mesocosm study that was conducted to investigate ecosystem and biogeochemical responses to ocean acidification. We measured copepod egg production rate, egg hatching success, adult female size and adult female antioxidant capacity (ORAC) as a function of acidification (fCO2 ~ 365-1231 μatm), and as a function of quantity and quality of their diet. We used an egg transplant experiment to reveal if transgenerational effects can alleviate the possible negative effects of ocean acidification on offspring development. We found significant negative effects of ocean acidification on adult female copepod size and egg hatching success. In addition, we found a threshold of fCO2 concentration (~ 1000 μatm), above which adaptive maternal effects cannot alleviate the negative effects of acidification on egg hatching and nauplii development. We did not find support for the hypothesis that insufficient food quantity (total particulate carbon ~ 55 μm) or quality (C : N) weakens the transgenerational effects. However, females with high ORAC produced eggs with high hatching success. Overall, these results indicate that A. bifilosa could be affected by projected near future CO2 levels.

  14. Sustainable harvest: managing plasticity for resilient crops

    PubMed Central

    Bloomfield, Justin A; Rose, Terry J; King, Graham J

    2014-01-01

    Maintaining crop production to feed a growing world population is a major challenge for this period of rapid global climate change. No consistent conceptual or experimental framework for crop plants integrates information at the levels of genome regulation, metabolism, physiology and response to growing environment. An important role for plasticity in plants is assisting in homeostasis in response to variable environmental conditions. Here, we outline how plant plasticity is facilitated by epigenetic processes that modulate chromatin through dynamic changes in DNA methylation, histone variants, small RNAs and transposable elements. We present examples of plant plasticity in the context of epigenetic regulation of developmental phases and transitions and map these onto the key stages of crop establishment, growth, floral initiation, pollination, seed set and maturation of harvestable product. In particular, we consider how feedback loops of environmental signals and plant nutrition affect plant ontogeny. Recent advances in understanding epigenetic processes enable us to take a fresh look at the crosstalk between regulatory systems that confer plasticity in the context of crop development. We propose that these insights into genotype × environment (G × E) interaction should underpin development of new crop management strategies, both in terms of information-led agronomy and in recognizing the role of epigenetic variation in crop breeding. PMID:24891039

  15. Instability mechanisms in swirling flows

    NASA Astrophysics Data System (ADS)

    Gallaire, F.; Chomaz, J.-M.

    2003-09-01

    We investigate the stability of the screened Rankine vortex with added plug flow where the azimuthal velocity decreases abruptly outside the core of the vortex. The jump in circulation is known to induce centrifugal and azimuthal Kelvin-Helmholtz instabilities. Their effect on the stability of the different azimuthal wave number m is discussed using physical considerations associated with asymptotic expansions and numerical computations of the dispersion relation. It is shown that the axial shear and centrifugal instability are active for all m, and that modes with |m|⩾2 are also destabilized by azimuthal shear. In contrast, the bending modes m=±1 are stabilized by a coupling with Kelvin waves in the core. Effects of rotation on the absolute/convective transition are also discussed. The absolute instability of positive helical modes is seen to be promoted by centrifugal instability and azimuthal shear.

  16. Microwave instability near transition energy

    SciTech Connect

    Wei, J.; Lee, S.Y.

    1989-01-01

    Monte Carlo simulation for the microwave instability agrees with analytic calculation solving the Vlasov equation, provided that bunch shape distortion due to coupling is taken into account. 9 refs., 2 figs.

  17. Interfacial interactions between plastic particles in plastics flotation.

    PubMed

    Wang, Chong-qing; Wang, Hui; Gu, Guo-hua; Fu, Jian-gang; Lin, Qing-quan; Liu, You-nian

    2015-12-01

    Plastics flotation used for recycling of plastic wastes receives increasing attention for its industrial application. In order to study the mechanism of plastics flotation, the interfacial interactions between plastic particles in flotation system were investigated through calculation of Lifshitz-van der Waals (LW) function, Lewis acid-base (AB) Gibbs function, and the extended Derjaguin-Landau-Verwey-Overbeek potential energy profiles. The results showed that van der Waals force between plastic particles is attraction force in flotation system. The large hydrophobic attraction, caused by the AB Gibbs function, is the dominant interparticle force. Wetting agents present significant effects on the interfacial interactions between plastic particles. It is found that adsorption of wetting agents promotes dispersion of plastic particles and decreases the floatability. Pneumatic flotation may improve the recovery and purity of separated plastics through selective adsorption of wetting agents on plastic surface. The relationships between hydrophobic attraction and surface properties were also examined. It is revealed that there exists a three-order polynomial relationship between the AB Gibbs function and Lewis base component. Our finding provides some insights into mechanism of plastics flotation. PMID:26337962

  18. Waves and instabilities in plasmas

    SciTech Connect

    Chen, L.

    1987-01-01

    The contents of this book are: Plasma as a Dielectric Medium; Nyquist Technique; Absolute and Convective Instabilities; Landau Damping and Phase Mixing; Particle Trapping and Breakdown of Linear Theory; Solution of Viasov Equation via Guilding-Center Transformation; Kinetic Theory of Magnetohydrodynamic Waves; Geometric Optics; Wave-Kinetic Equation; Cutoff and Resonance; Resonant Absorption; Mode Conversion; Gyrokinetic Equation; Drift Waves; Quasi-Linear Theory; Ponderomotive Force; Parametric Instabilities; Problem Sets for Homework, Midterm and Final Examinations.

  19. Material Instabilities in Particulate Systems

    NASA Technical Reports Server (NTRS)

    Goddard, J. D.

    1999-01-01

    Following is a brief summary of a theoretical investigation of material (or constitutive) instability associated with shear induced particle migration in dense particulate suspensions or granular media. It is shown that one can obtain a fairly general linear-stability analysis, including the effects of shear-induced anisotropy in the base flow as well as Reynolds dilatancy. A criterion is presented here for simple shearing instability in the absence of inertia and dilatancy.

  20. Flare instability and driving mechanism

    NASA Astrophysics Data System (ADS)

    Raychaudhuri, Probhas

    A mechanism is described for the generation of solar flares in which a Buneman instability is produced by electrons moving faster than thermal speed. A trapped population of particles accelerates in the magnetic field of active solar regions causing a streaming of ions relative to electrons which moves and heats the electrons. The theoretical argument also concludes that instability at the inner solar core directly bears on solar activities at the outer heliosphere.

  1. Stability and instability in evolution.

    PubMed

    Benci, V; Galleni, L

    1998-10-21

    In this paper we propose a mechanism which tries to explain the presence of periods of stability and instability which occur during the evolution of living forms. According to the Gaia hypothesis there are feedback mechanisms which stabilise the biosphere. Adding the presence of parameters which are out of control of the biosphere and of different time-scales, we propose a model which might explain the periods of instability. PMID:9790828

  2. Aerodynamic instability: A case history

    NASA Technical Reports Server (NTRS)

    Eisenmann, R. C.

    1985-01-01

    The identification, diagnosis, and final correction of complex machinery malfunctions typically require the correlation of many parameters such as mechanical construction, process influence, maintenance history, and vibration response characteristics. The progression is reviewed of field testing, diagnosis, and final correction of a specific machinery instability problem. The case history presented addresses a unique low frequency instability problem on a high pressure barrel compressor. The malfunction was eventually diagnosed as a fluidic mechanism that manifested as an aerodynamic disturbance to the rotor assembly.

  3. Shoulder instability surgery in Norway

    PubMed Central

    2012-01-01

    Background and purpose In January 2008, we established the Norwegian Register for Shoulder Instability Surgery. We report on the establishment, the baseline data, and the results at 1-year follow-up. Methods Primary and revision shoulder stabilization is reported by the surgeon on a 1-page paper form containing the patient's history of shoulder injury, clinical findings, and perioperative findings. The WOSI questionnaire for self-assessment of shoulder function is completed at baseline and at follow-up after 1, 2, and 5 years. To evaluate the completeness of registration, we compared our data with those in the Norwegian Patient Registry (NPR). Results The NPR reported 39 hospitals performing shoulder stabilizations. 20 of these started to report to our register during 2009, and 464 procedures (404 primary, 59 revisions) were included up to December 31, 2009, which represented 54% of the procedures reported to NPR. Of the 404 primary procedures, 83% were operations due to anterior instability, 10% were operations due to posterior instability, and 7% were operations due to multidirectional instability. Arthroscopic soft tissue techniques were used in 88% of the patients treated for primary anterior instability and open coracoid transfer was used in 10% of such patients. At 1-year follow-up of 213 patients, we found a statistically significantly improved WOSI score in all types of instability. 10% of the patients treated with arthroscopic anterior labral repair and 16% treated with arthroscopic posterior labral repair reported recurrent instability. No statistically significant difference in functional improvement or rate of recurrence was found between these groups. Interpretation The functional results are in accordance with those in previous studies. However, the incidence of recurrent instability 1 year after arthroscopic labral repair is higher than expected. PMID:22112155

  4. Plasticity and Recovery After Dorsal Column Spinal Cord Injury in Nonhuman Primates.

    PubMed

    Reed, Jamie L; Liao, Chia-Chi; Qi, Hui-Xin; Kaas, Jon H

    2016-01-01

    Here, we review recent work on plasticity and recovery after dorsal column spinal cord injury in nonhuman primates. Plasticity in the adult central nervous system has been established and studied for the past several decades; however, capacities and limits of plasticity are still under investigation. Studies of plasticity include assessing multiple measures before and after injury in animal models. Such studies are particularly important for improving recovery after injury in patients. In summarizing work by our research team and others, we suggest how the findings from plasticity studies in nonhuman primate models may affect therapeutic interventions for conditions involving sensory loss due to spinal cord injury. PMID:27578996

  5. Plasticity and Recovery After Dorsal Column Spinal Cord Injury in Nonhuman Primates

    PubMed Central

    Reed, Jamie L.; Liao, Chia-Chi; Qi, Hui-Xin; Kaas, Jon H.

    2016-01-01

    Here, we review recent work on plasticity and recovery after dorsal column spinal cord injury in nonhuman primates. Plasticity in the adult central nervous system has been established and studied for the past several decades; however, capacities and limits of plasticity are still under investigation. Studies of plasticity include assessing multiple measures before and after injury in animal models. Such studies are particularly important for improving recovery after injury in patients. In summarizing work by our research team and others, we suggest how the findings from plasticity studies in nonhuman primate models may affect therapeutic interventions for conditions involving sensory loss due to spinal cord injury. PMID:27578996

  6. Instability in Three-Dimensional Magnetohydrodynamic Flows of an Electrically Conducting Fluid

    NASA Astrophysics Data System (ADS)

    Zakir, Hussain; Liu, Chan; Zhang, Nianmei; Ni, Mingjiu

    2013-12-01

    The three-dimensional instability of an electrically conducting fluid between two parallel plates affected by an imposed transversal magnetic field is numerically investigated by a Chebyshev collocation method. The QZ method is utilized to obtain neutral curves of the linear instability. The details of instability are analyzed by solving the generalized Orr-Sommerfeld equation. The critical Reynolds number Rec, the stream-wise and span-wise critical wave numbers αc and βc are obtained for a wide range of Hartmann number Ha. The effects of Lorentz force and span-wise perturbation on three-dimensional instability are investigated. The results show that magnetic field would suppress the instability and critical Reynolds number tends to be larger than that for two-dimensional instability.

  7. Vertical Instability at IPNS RCS.

    SciTech Connect

    Wang, S.; Brumwell, F. R.; Dooling, J. C.; Harkay, K. C.; Kustom, R.; McMichael, G. E.; Middendorf, M. E.; Nassiri, A.; Accelerator Systems Division

    2008-01-01

    The rapid cycling synchrotron (RCS) of the intense pulsed neutron source (IPNS) at ANL accelerates > 3.0 times 10{sup 12} protons from 50 MeV to 450 MeV with 30-Hz repetition frequency. During the acceleration cycle, the rf frequency varies from 2.21 MHz to 5.14 MHz. Presently, the beam current is limited by a vertical instability. By analyzing turn-by-turn beam position monitor (BPM) data, large- amplitude mode 0 and mode 1 vertical beam centroid oscillations were observed in the later part of the acceleration cycle. The oscillations start in the tail of the bunch, build up, and remain localized in the tail half of the bunch. This vertical instability was compared with a head-tail instability that was intentionally induced in the RCS by adjusting the trim sextupoles. It appears that our vertical instability is not a classical head-tail instability [1]. More data analysis and experiments were performed to characterize the instability.

  8. Pattern Formation in Convective Instabilities

    NASA Astrophysics Data System (ADS)

    Friedrich, R.; Bestehorn, M.; Haken, H.

    The present article reviews recent progress in the study of pattern formation in convective instabilities. After a brief discussion of the relevant basic hydrodynamic equations as well as a short outline of the mathematical treatment of pattern formation in complex systems the self-organization of spatial and spatio-temporal structures due to convective instabilities is considered. The formation of various forms of convective patterns arising in the Bénard experiment, i.e. in a horizontal fluid layer heated from below, is discussed. Then the review considers pattern formation in the Bénard instability in spherical geometries. In that case it can be demonstrated how the interaction among several convective cells may lead to time dependent as well as chaotic evolution of the spatial structures. Finally, the convective instability in a binary fluid mixture is discussed. In contrast to the instability in a single component fluid the instability may be oscillatory. In that case convection sets in in the form of travelling wave patterns which in addition to a complicated and chaotic temporal behaviour exhibit more or less spatial irregularity already close to threshold.

  9. Elastic instabilities in rubber

    NASA Astrophysics Data System (ADS)

    Gent, Alan

    2009-03-01

    Materials that undergo large elastic deformations can exhibit novel instabilities. Several examples are described: development of an aneurysm on inflating a rubber tube; non-uniform stretching on inflating a spherical balloon; formation of internal cracks in rubber blocks at a critical level of triaxial tension or when supersaturated with a dissolved gas; surface wrinkling of a block at a critical amount of compression; debonding or fracture of constrained films on swelling, and formation of ``knots'' on twisting stretched cylindrical rods. These various deformations are analyzed in terms of a simple strain energy function, using Rivlin's theory of large elastic deformations, and the results are compared with experimental measurements of the onset of unstable states. Such comparisons provide new tests of Rivlin's theory and, at least in principle, critical tests of proposed strain energy functions for rubber. Moreover the onset of highly non-uniform deformations has serious implications for the fatigue life and fracture resistance of rubber components. [4pt] References: [0pt] R. S. Rivlin, Philos. Trans. Roy. Soc. Lond. Ser. A241 (1948) 379--397. [0pt] A. Mallock, Proc. Roy. Soc. Lond. 49 (1890--1891) 458--463. [0pt] M. A. Biot, ``Mechanics of Incremental Deformations'', Wiley, New York, 1965. [0pt] A. N. Gent and P. B. Lindley, Proc. Roy. Soc. Lond. A 249 (1958) 195--205. [0pt] A. N. Gent, W. J. Hung and M. F. Tse, Rubb. Chem. Technol. 74 (2001) 89--99. [0pt] A. N. Gent, Internatl. J. Non-Linear Mech. 40 (2005) 165--175.

  10. Instability of enclosed horizons

    NASA Astrophysics Data System (ADS)

    Kay, Bernard S.

    2015-03-01

    We point out that there are solutions to the scalar wave equation on dimensional Minkowski space with finite energy tails which, if they reflect off a uniformly accelerated mirror due to (say) Dirichlet boundary conditions on it, develop an infinite stress-energy tensor on the mirror's Rindler horizon. We also show that, in the presence of an image mirror in the opposite Rindler wedge, suitable compactly supported arbitrarily small initial data on a suitable initial surface will develop an arbitrarily large stress-energy scalar near where the two horizons cross. Also, while there is a regular Hartle-Hawking-Israel-like state for the quantum theory between these two mirrors, there are coherent states built on it for which there are similar singularities in the expectation value of the renormalized stress-energy tensor. We conjecture that in other situations with analogous enclosed horizons such as a (maximally extended) Schwarzschild black hole in equilibrium in a (stationary spherical) box or the (maximally extended) Schwarzschild-AdS spacetime, there will be similar stress-energy singularities and almost-singularities—leading to instability of the horizons when gravity is switched on and matter and gravity perturbations are allowed for. All this suggests it is incorrect to picture a black hole in equilibrium in a box or a Schwarzschild-AdS black hole as extending beyond the past and future horizons of a single Schwarzschild (/Schwarzschild-AdS) wedge. It would thus provide new evidence for 't Hooft's brick wall model while seeming to invalidate the picture in Maldacena's ` Eternal black holes in AdS'. It would thereby also support the validity of the author's matter-gravity entanglement hypothesis and of the paper ` Brick walls and AdS/CFT' by the author and Ortíz.

  11. An analytical description of hydrodynamic instabilities

    NASA Astrophysics Data System (ADS)

    Bulanov, S. V.; Sasorov, P. V.

    The proper approach to the investigation of the nonlinear stage of hydrodynamic instabilities in a plasma has been discussed. Both the Buneman instability and the beam instability have been considered. A similarity between the nonlinear stage of the beam plasma instability and the process of self-modulation and self-focusing of nonlinear waves is revealed.

  12. Understanding Etna flank instability through numerical models

    NASA Astrophysics Data System (ADS)

    Apuani, Tiziana; Corazzato, Claudia; Merri, Andrea; Tibaldi, Alessandro

    2013-02-01

    mainly devoted to evaluate the effect of topography, geometry and rheological behaviour of the structural units. The 3D numerical model, extended 40 × 60 km, was implemented to simulate the volcano deformation pattern. First, the role of the Pleistocene subetnean clays was investigated, then, two "structural weakness zones" - the Pernicana Fault system and the NE rift - were introduced and their effects on the flank instability evaluated. Two extreme hydrogeological conditions, drained and undrained, were analysed. The results are expressed in terms of stress-strain field, displacement pattern, plasticity states and shear strain increments. Two main instability mechanisms were identified: one at shallow depth, with the sliding surface located inside the subetnean Quaternary clay, and another deep-seated mechanism with a not continuous and less evident sliding surface, developed inside the Apennine-Maghrebian Chain flysch, bordered by active structures. Both mechanisms contribute to explain the present deformation pattern and some of the main structures of the Etna flank. The effect of magma pressure exerted on the active dyke walls during eruptions was then simulated and relations between magmatic activity and flank instability were preliminarily investigated.

  13. Use of recycled plastics in wood plastic composites - a review.

    PubMed

    Kazemi Najafi, Saeed

    2013-09-01

    The use of recycled and waste thermoplastics has been recently considered for producing wood plastic composites (WPCs). They have great potential for WPCs manufacturing according to results of some limited researches. This paper presents a detailed review about some essential properties of waste and recycled plastics, important for WPCs production, and of research published on the effect of recycled plastics on the physical and mechanical properties of WPCs. PMID:23777666

  14. Competing Turing and Faraday Instabilities in Longitudinally Modulated Passive Resonators

    NASA Astrophysics Data System (ADS)

    Copie, François; Conforti, Matteo; Kudlinski, Alexandre; Mussot, Arnaud; Trillo, Stefano

    2016-04-01

    We experimentally investigate the interplay of Turing (modulational) and Faraday (parametric) instabilities in a bistable passive nonlinear resonator. The Faraday branch is induced via parametric resonance owing to a periodic modulation of the resonator dispersion. We show that the bistable switching dynamics is dramatically affected by the competition between the two instability mechanisms, which dictates two completely novel scenarios. At low detunings from resonance, switching occurs between the stable stationary lower branch and the Faraday-unstable upper branch, whereas at high detunings we observe the crossover between the Turing and Faraday periodic structures. The results are well explained in terms of the universal Lugiato-Lefever model.

  15. Competing Turing and Faraday Instabilities in Longitudinally Modulated Passive Resonators.

    PubMed

    Copie, François; Conforti, Matteo; Kudlinski, Alexandre; Mussot, Arnaud; Trillo, Stefano

    2016-04-01

    We experimentally investigate the interplay of Turing (modulational) and Faraday (parametric) instabilities in a bistable passive nonlinear resonator. The Faraday branch is induced via parametric resonance owing to a periodic modulation of the resonator dispersion. We show that the bistable switching dynamics is dramatically affected by the competition between the two instability mechanisms, which dictates two completely novel scenarios. At low detunings from resonance, switching occurs between the stable stationary lower branch and the Faraday-unstable upper branch, whereas at high detunings we observe the crossover between the Turing and Faraday periodic structures. The results are well explained in terms of the universal Lugiato-Lefever model. PMID:27104711

  16. Solar wind driven dust acoustic instability with Lorentzian kappa distribution

    SciTech Connect

    Arshad, Kashif; Ehsan, Zahida; Khan, S. A.; Mahmood, S.

    2014-02-15

    In a three species electron-ion-dust plasma following a generalized non-Maxwellian distribution function (Lorentzian or kappa), it is shown that a kinetic instability of dust-acoustic mode exists. The instability threshold is affected when such (quasineutral) plasma permeates through another static plasma. Such case is of interest when the solar wind is streaming through the cometary plasma in the presence of interstellar dust. In the limits of phase velocity of the waves larger and smaller than the thermal velocity of dust particles, the dispersion properties and growth rate of dust-acoustic mode are investigated analytically with validation via numerical analysis.

  17. Modulation instability of laser pulse in magnetized plasma

    SciTech Connect

    Jha, Pallavi; Kumar, Punit; Raj, Gaurav; Upadhyaya, Ajay K.

    2005-12-15

    Modulation instability of a laser pulse propagating through transversely magnetized underdense plasma is studied. It is observed that interaction of laser radiation with plasma in the presence of uniform magnetic field results in an additional perturbed transverse plasma current density along with the relativistic and ponderomotive nonlinear current densities, thus affecting the modulational interaction. In the plane wave limit it is observed that modulational interaction is more stable for magnetized plasma as compared to the unmagnetized case. The analysis shows that there is a significant reduction in the growth rate of modulation instability over a given range of unstable wave numbers due to magnetization of plasma.

  18. Monitoring the abundance of plastic debris in the marine environment

    PubMed Central

    Ryan, Peter G.; Moore, Charles J.; van Franeker, Jan A.; Moloney, Coleen L.

    2009-01-01

    Plastic debris has significant environmental and economic impacts in marine systems. Monitoring is crucial to assess the efficacy of measures implemented to reduce the abundance of plastic debris, but it is complicated by large spatial and temporal heterogeneity in the amounts of plastic debris and by our limited understanding of the pathways followed by plastic debris and its long-term fate. To date, most monitoring has focused on beach surveys of stranded plastics and other litter. Infrequent surveys of the standing stock of litter on beaches provide crude estimates of debris types and abundance, but are biased by differential removal of litter items by beachcombing, cleanups and beach dynamics. Monitoring the accumulation of stranded debris provides an index of debris trends in adjacent waters, but is costly to undertake. At-sea sampling requires large sample sizes for statistical power to detect changes in abundance, given the high spatial and temporal heterogeneity. Another approach is to monitor the impacts of plastics. Seabirds and other marine organisms that accumulate plastics in their stomachs offer a cost-effective way to monitor the abundance and composition of small plastic litter. Changes in entanglement rates are harder to interpret, as they are sensitive to changes in population sizes of affected species. Monitoring waste disposal on ships and plastic debris levels in rivers and storm-water runoff is useful because it identifies the main sources of plastic debris entering the sea and can direct mitigation efforts. Different monitoring approaches are required to answer different questions, but attempts should be made to standardize approaches internationally. PMID:19528052

  19. Nova Experiments Examining Raleigh-Taylor Instability in Materials with Strength

    SciTech Connect

    Weber, S.V.; Kalantar, D.H.; Colvin, J.D.; Gold, D.M.; Mikaelian, K.O.; Remington, B.A.; Wiley, L.G.

    1999-10-06

    Material strength can affect the growth of the Rayleigh-Taylor instability in solid materials, where growth occurs through plastic flow. In order to study this effect at megabar pressures, we have shocked metal foils using hohlraum x-ray drive on Nova, and observed the growth of pre-imposed modulations with x-ray radiography. Previous experiments employing Cu foils did not conclusively show strength effects for resolvable wavelengths. Therefore, we have redesigned the experiment to use aluminum foils. As aluminum has higher specific strength at pressures {approx}1 Mbar, the new design is predicted to show growth reduction due to strength of at least a factor of two for some wavelengths in the observable range of 10 - 50 {micro}m. We have also modified the drive history to extend the interval of uniform acceleration and to reduce the risk of melting the foils with coalesced shocks. The design changes, as well as Nova operational constraints, limit peak pressures to 1-1.5 Mbar. Foil surface motion has been measured with high sensitivity by laser interferometry to look for thermal expansion due to preheat. We have continued to pursue dynamic x-ray diffraction as the most definitive measurement of crystal state.

  20. Direct liquefaction of plastics and coprocessing of coal with plastics

    SciTech Connect

    Huffman, G.P.; Feng, Z.; Mahajan, V.

    1995-12-31

    The objectives of this work were to optimize reaction conditions for the direct liquefaction of waste plastics and the coprocessing of coal with waste plastics. In previous work, the direct liquefaction of medium and high density polyethylene (PE), polypropylene (PPE), poly(ethylene terephthalate) (PET), and a mixed plastic waste, and the coliquefaction of these plastics with coals of three different ranks was studied. The results established that a solid acid catalyst (HZSM-5 zeolite) was highly active for the liquefaction of the plastics alone, typically giving oil yields of 80-95% and total conversions of 90-100% at temperatures of 430-450 {degrees}C. In the coliquefaction experiments, 50:50 mixtures of plastic and coal were used with a tetralin solvent (tetralin:solid = 3:2). Using approximately 1% of the HZSM-5 catalyst and a nanoscale iron catalyst, oil yields of 50-70% and total conversion of 80-90% were typical. In the current year, further investigations were conducted of the liquefaction of PE, PPE, and a commingled waste plastic obtained from the American Plastics Council (APC), and the coprocessing of PE, PPE and the APC plastic with Black Thunder subbituminous coal. Several different catalysts were used in these studies.

  1. Plastic Surgery and Suicide: A Clinical Guide for Plastic Surgeons.

    PubMed

    Reddy, Vikram; Coffey, M Justin

    2016-08-01

    Several studies have identified an increased risk of suicide among patient populations which a plastic surgeon may have a high risk of encountering: women undergoing breast augmentation, cosmetic surgery patients, and breast cancer patients. No formal guidelines exist to assist a plastic surgeon when faced with such a patient, and not every plastic surgery team has mental health clinicians that are readily accessible for consultation or referral. The goal of this clinical guide is to offer plastic surgeons a set of practical approaches to manage potentially suicidal patients. In addition, the authors review a screening tool, which can assist surgeons when encountering high-risk patients. PMID:27622096

  2. Plastic Surgery and Suicide: A Clinical Guide for Plastic Surgeons

    PubMed Central

    Coffey, M. Justin

    2016-01-01

    Summary: Several studies have identified an increased risk of suicide among patient populations which a plastic surgeon may have a high risk of encountering: women undergoing breast augmentation, cosmetic surgery patients, and breast cancer patients. No formal guidelines exist to assist a plastic surgeon when faced with such a patient, and not every plastic surgery team has mental health clinicians that are readily accessible for consultation or referral. The goal of this clinical guide is to offer plastic surgeons a set of practical approaches to manage potentially suicidal patients. In addition, the authors review a screening tool, which can assist surgeons when encountering high-risk patients. PMID:27622096

  3. Plastic star coupler

    NASA Astrophysics Data System (ADS)

    Yuuki, Hayato; Ito, Takeharu; Sugimoto, Tetsuo

    1991-12-01

    We applied an ultrasonic welding method for the bonding of plastic fibers, and obtained many types of optical star couplers for optical communication systems. It enables the manufacturing of optical components with low loss without damaging the clad layer except for the welding surface. Therefore, they have some merits, such as low loss, small size, light weight, and low cost. The 4-ports (2 X 2) star coupler of 1000 micrometers diam APF has 0.7 dB excess loss at most, and the welding length is 20 mm.

  4. Fabrication of plastic biochips

    SciTech Connect

    Saaem, Ishtiaq; Ma, Kuo-Sheng; Alam, S. Munir; Tian Jingdong

    2010-07-15

    A versatile surface functionalization procedure based on rf magnetron sputtering of silica was performed on poly(methylmethacrylate), polycarbonate, polypropylene, and cyclic olefin copolymers (Topas 6015). The hybrid thermoplastic surfaces were characterized by x-ray photoelectron spectrometer analysis and contact angle measurements. The authors then used these hybrid materials to perform a sandwich assay targeting an HIV-1 antibody using fluorescent detection and biotinylated peptides immobilized using the bioaffinity of biotin-neutravidin. They found a limit of detection similar to arrays on glass surfaces and believed that this plastic biochip platform may be used for the development of disposable immunosensing and diagnostic applications.

  5. History of reinforced plastics

    SciTech Connect

    Milewski, J.V.; Rosato, D.V.

    1981-01-01

    This history of reinforced plastics is told by combining the individual histories of each reinforcement and the way in which they added to and changed the direction and rate of growth of the industry. The early history is based on all resins, fillers, and fibers found in nature. Then came the Baekeland revolution with the first synthetic resin which lasted about 25 years, at which time synthetic fiber glass and polyester resin dramatically changed the industry. Now, for the 1980s, the high modulus fibers developed 10 to 20 years ago are reshaping the industry. 32 figures.

  6. ABS plastic RPCs

    SciTech Connect

    Ables, E.; Bionta, R.; Olson, H.; Ott, L.; Parker, E.; Wright, D.; Wuest, C

    1996-02-01

    After investigating a number of materials, we discovered that an ABS plastic doped with a conducting polymer performs well as the resistive electrode in a narrow gap RPC (resistive plate chamber). Operating in the streamer mode, we find efficiencies of 90-96% with low noise and low strip multiplicities. We have also studied a variety of operating gases and found that a mixture containing SF{sub 6}, a non-ozone depleting gas, argon and isobutane gives good streamer mode performance, even with isobutane concentrations of 20% or less.

  7. Psychotherapy and brain plasticity

    PubMed Central

    Collerton, Daniel

    2013-01-01

    In this paper, I will review why psychotherapy is relevant to the question of how consciousness relates to brain plasticity. A great deal of the research and theorizing on consciousness and the brain, including my own on hallucinations for example (Collerton and Perry, 2011) has focused upon specific changes in conscious content which can be related to temporal changes in restricted brain systems. I will argue that psychotherapy, in contrast, allows only a focus on holistic aspects of consciousness; an emphasis which may usefully complement what can be learnt from more specific methodologies. PMID:24046752

  8. Advances in engineering plastics

    SciTech Connect

    Leonard, L.

    1997-12-01

    New polymers are being commercialized in record numbers, offering the product designer a new realm of possibilities, and promising tough competition to the traditional engineering resins. Most of the growth is in single-site catalyzed resins. Metallocene (and non-metallocene) single-site catalysts enhance polymer architecture to generate highly uniform molecules, and even permit tailoring new categories of polymers. These new materials include the truly unique aliphatic polyketone, syndiotactic polystyrene (SPS); polyethylene naphthalate (PEN) resins; and novel variations of established polymers. This article provides a closer look at these newcomers to the plastics marketplace, with an emphasis on their properties and potential applications.

  9. The Effects of Contact Conditions on the Onset of Shear Instability in Cold-Spray

    NASA Astrophysics Data System (ADS)

    Meng, Fanchao; Aydin, Huseyin; Yue, Stephen; Song, Jun

    2015-04-01

    Using ABAQUS/Explicit, the effects of contact conditions between the particle and substrate, including tangential friction, normal constraint, and contact geometry on the plastic deformation during the cold-spray process are studied. It was found that the onset of shear instability, an event often used to indicate the establishment of bonding, is very sensitive to the choice of contact conditions. This suggests that the onset of shear instability does not serve as an accurate means to identify the plasticity threshold responsible for bonding. On the other hand, it is demonstrated that the evolution of the overall equivalent plastic strain (i.e., ) and the overall von Mises stress, being linearly proportional to each other, are both independent of contact conditions. Furthermore, it is shown that an energy value, defined as the product of the and the von Mises stress integrated over all particle elements, can quantitatively represent the energy dissipated via plastic deformation while being independent of contact conditions. The and associated energy value as defined may provide robust tools to assess the plasticity and the consequent bonding during cold-spray.

  10. Measurements of turbulent mixing due to Kelvin-Helmholtz instability in high-energy-density plasmas

    NASA Astrophysics Data System (ADS)

    Smalyuk, V. A.; Hurricane, O. A.; Hansen, J. F.; Langstaff, G.; Martinez, D.; Park, H.-S.; Raman, K.; Remington, B. A.; Robey, H. F.; Schilling, O.; Wallace, R.; Elbaz, Y.; Shimony, A.; Shvarts, D.; Di Stefano, C.; Drake, R. P.; Marion, D.; Krauland, C. M.; Kuranz, C. C.

    2013-03-01

    Kelvin-Helmholtz (KH) turbulent mixing measurements were performed in experiments on the OMEGA Laser Facility [T.R. Boehly et al., Opt. Commun. 133 (1997) 495]. In these experiments, laser-driven shock waves propagated through low-density plastic foam placed on top of a higher-density plastic foil. Behind the shock front, lower-density foam plasma flowed over the higher-density plastic plasma. The interface between the foam and plastic was KH unstable. The experiments were performed with pre-imposed, sinusoidal 2D perturbations, and broadband 3D perturbations due to surface roughness at the interface between the plastic and foam. KH instability growth was measured using X-ray, point-projection radiography. The mixing layer caused by the KH instability with layer width up to ˜100 μm was observed at a location ˜1 mm behind the shock front. The measured mixing layer width was in good agreement with simulations using a K-L turbulent mixing model in the two-dimensional ARES hydrodynamics code. In the definition of the K-L model K stands for the specific turbulent kinetic (K) energy, and L for the scale length (L) of the turbulence.

  11. Presynaptic long-term plasticity

    PubMed Central

    Yang, Ying; Calakos, Nicole

    2013-01-01

    Long-term synaptic plasticity is a major cellular substrate for learning, memory, and behavioral adaptation. Although early examples of long-term synaptic plasticity described a mechanism by which postsynaptic signal transduction was potentiated, it is now apparent that there is a vast array of mechanisms for long-term synaptic plasticity that involve modifications to either or both the presynaptic terminal and postsynaptic site. In this article, we discuss current and evolving approaches to identify presynaptic mechanisms as well as discuss their limitations. We next provide examples of the diverse circuits in which presynaptic forms of long-term synaptic plasticity have been described and discuss the potential contribution this form of plasticity might add to circuit function. Finally, we examine the present evidence for the molecular pathways and cellular events underlying presynaptic long-term synaptic plasticity. PMID:24146648

  12. Stress- and Allostasis-Induced Brain Plasticity

    PubMed Central

    McEwen, Bruce S.; Gianaros, Peter J.

    2014-01-01

    The brain is the key organ of stress processes. It determines what individuals will experience as stressful, it orchestrates how individuals will cope with stressful experiences, and it changes both functionally and structurally as a result of stressful experiences. Within the brain, a distributed, dynamic, and plastic neural circuitry coordinates, monitors, and calibrates behavioral and physiological stress response systems to meet the demands imposed by particular stressors. These allodynamic processes can be adaptive in the short term (allostasis) and maladaptive in the long term (allostatic load). Critically, these processes involve bidirectional signaling between the brain and body. Consequently, allostasis and allostatic load can jointly affect vulnerability to brain-dependent and stress-related mental and physical health conditions. This review focuses on the role of brain plasticity in adaptation to, and pathophysiology resulting from, stressful experiences. It also considers interventions to prevent and treat chronic and prevalent health conditions via allodynamic brain mechanisms. PMID:20707675

  13. Modeling orthotropic elasticity, localized plasticity and fracture in trabecular bone

    NASA Astrophysics Data System (ADS)

    O'Connor, D. T.; Elkhodary, K. I.; Fouad, Y.; Greene, M. S.; Sabet, F. A.; Qian, J.; Zhang, Y.; Liu, W. K.; Jasiuk, I.

    2016-05-01

    This work develops a model for the mechanical response of trabecular bone including plasticity, damage and fracture. It features a resultant lamellar orientation that captures trabecular strut anisotropic elasticity, and introduces asymmetric J2 plasticity with isotropic hardening to capture evolving strut tensile and compressive dissipative properties. A continuum compatibility based damage and fracture criterion is also proposed to model fracture surface generation. We investigated fracture of a trabecular bone network under a compressive load, for which failure modes of both tension and compression were identified at the strut level. The predicted trabecular network response was found to fall within the range of experimental results reported in literature. We also investigated the response of idealized struts under compression, tension and bending using our model. Individual struts were found to exhibit micro-buckling under compression and micro-necking under tension. These instabilities are however masked by the multiplicity and complexity of strut orientations at the trabecular network level.

  14. Modeling orthotropic elasticity, localized plasticity and fracture in trabecular bone

    NASA Astrophysics Data System (ADS)

    O'Connor, D. T.; Elkhodary, K. I.; Fouad, Y.; Greene, M. S.; Sabet, F. A.; Qian, J.; Zhang, Y.; Liu, W. K.; Jasiuk, I.

    2016-09-01

    This work develops a model for the mechanical response of trabecular bone including plasticity, damage and fracture. It features a resultant lamellar orientation that captures trabecular strut anisotropic elasticity, and introduces asymmetric J2 plasticity with isotropic hardening to capture evolving strut tensile and compressive dissipative properties. A continuum compatibility based damage and fracture criterion is also proposed to model fracture surface generation. We investigated fracture of a trabecular bone network under a compressive load, for which failure modes of both tension and compression were identified at the strut level. The predicted trabecular network response was found to fall within the range of experimental results reported in literature. We also investigated the response of idealized struts under compression, tension and bending using our model. Individual struts were found to exhibit micro-buckling under compression and micro-necking under tension. These instabilities are however masked by the multiplicity and complexity of strut orientations at the trabecular network level.

  15. Polyolefins as additives in plastics

    SciTech Connect

    Deanin, R.D.

    1993-12-31

    Polyolefins are not only major commodity plastics - they are also very useful as additives, both in other polyolefins and also in other types of plastics. This review covers ethylene, propylene, butylene and isobutylene polymers, in blends with each other, and as additives to natural rubber, styrene/butadiene rubber, polystyrene, polyvinyl chloride, polymethyl methacrylate, polyphenylene oxide, polycarbonate, thermoplastic polyesters, polyurethanes, polyamides, and mixed automotive plastics recycling.

  16. Critical Dynamics of Burst Instabilities in the Portevin-Le Chatelier Effect

    SciTech Connect

    D'Anna, Gianfranco; Nori, Franco

    2000-11-06

    We investigate the Portevin-Le Chatelier effect (PLC), by compressing Al-Mg alloys in a very large deformation range, and interpret the results from the viewpoint of phase transitions and critical phenomena. The system undergoes two dynamical phase transitions between intermittent (or ''jerky'') and ''laminar'' plastic dynamic phases. Near these two dynamic critical points, the order parameter 1/{tau} of the PLC effect exhibits large fluctuations, and ''critical slowing down'' (i.e., the number {tau} of bursts, or plastic instabilities, per unit time slows down considerably).

  17. Fermi liquids near Pomeranchuk instabilities

    NASA Astrophysics Data System (ADS)

    Reidy, Kelly Elizabeth

    We explore features of a Fermi liquid near generalized Pomeranchuk instabilities (PIs) starting from both ordered and disordered phases. These PIs can be viewed as quantum critical points in parameter space, and thus provide an alternate viewpoint on quantum criticality. We employ the tractable crossing symmetric equation method, which is a non-perturbative diagrammatic many-particle method used to calculate the Fermi liquid interaction functions and scattering amplitudes. We consider both repulsive and attractive underlying interactions of arbitrary strength. Starting from a ferromagnetically ordered ground state, we find that upon approach to an s-wave instability in one critical channel, the system simultaneously approaches instabilities in non-critical channels. We study origins and implications of this "quantum multicriticality". We also find that a nematic (non-s-wave) instability precedes and is driven by Pomeranchuk instabilities in both the s-wave spin and density channels. Finally, we discuss potential applications of our results to physical systems, such as ferromagnetic superconductors.

  18. The Energetics of Centrifugal Instability

    NASA Astrophysics Data System (ADS)

    Dewar, W. K.; Jiao, Y.

    2014-12-01

    A recent study has argued that the California Undercurrent, and poleward eastern boundary currents in general, generate mixing events through centrifugal instability (CI). Conditions favorable for CI are created by the strong horizontal shears developed in turbulent bottom layers of currents flowing in the direction of topographic waves. At points of abrupt topographic change, like promontories and capes, the coastal current separates from the boundary and injects gravitationally stable but dynamically unstable flow into the interior. The resulting finite amplitude development of the instability involves overturnings and diabatic mixing. The purpose of this study is to examine the energetics of CI in order to characterize it as has been done for other instabilities and develop a framework in which to estimate its regional and global impacts. We argue that CI is roughly twice as efficient at mixing as is Kelvin-Helmholtz instability, and that roughly 10% of the initial energy in a CUC-like current is lost to either local mixing or the generation of unbalanced flows. The latter probably leads to non-local mixing. Thus centrifugal instability is an effective process by which energy is lost from the balanced flow and spent in mixing neighboring water masses. We argue the importance of the mixing is regional in nature, but of less importance to the global budgets given its regional specificity.

  19. Transient growth of droplet instabilities in a stream

    SciTech Connect

    Jalaal, M. E-mail: m-jalaal@yahoo.com; Mehravaran, K.

    2014-01-15

    Droplet deformation is the first stage of all aerodynamically induced-breakups, considerably affecting the characteristics of the atomization. In the present study, using an adaptive volume of fluid method, two and three-dimensional direct numerical simulations have been performed to understand droplet deformation. A high Reynolds number and a range of relatively high Weber numbers are chosen, addressing the shear breakup of droplets in a stream. The study is focused on the initiation and growth of instabilities over the droplet. The role of Kelvin-Helmholtz and Rayleigh-Taylor instabilities in wave formation and azimuthal transverse modulation are shown and the obtained results for the most amplified wave-numbers are compared with instability theories for zero and non-zero vorticity layers. The present results for the most amplified wave-numbers and deformation topologies are in good agreement with the previous experimental results.

  20. Mechanisms and Clinical Applications of Genome Instability in Multiple Myeloma

    PubMed Central

    Cagnetta, Antonia; Lovera, Davide; Grasso, Raffaella; Colombo, Nicoletta; Canepa, Letizia; Ballerini, Filippo; Calvio, Marino; Miglino, Maurizio; Gobbi, Marco; Lemoli, Roberto; Cea, Michele

    2015-01-01

    Ongoing genomic instability represents a hallmark of multiple myeloma (MM) cells, which manifests largely as whole chromosome- or translocation-based aneuploidy. Importantly, although it supports tumorigenesis, progression and, response to treatment in MM patients, it remains one of the least understood components of malignant transformation in terms of molecular basis. Therefore these aspects make the comprehension of genomic instability a pioneering strategy for novel therapeutic and clinical speculations to use in the management of MM patients. Here we will review mechanisms mediating genomic instability in MM cells with an emphasis placed on pathogenic mutations affecting DNA recombination, replication and repair, telomere function and mitotic regulation of spindle attachment, centrosome function, and chromosomal segregation. We will discuss the mechanisms by which genetic aberrations give rise to multiple pathogenic events required for myelomagenesis and conclude with a discussion of the clinical applications of these findings in MM patients. PMID:26579543

  1. Driving factors of electro-convective instability in concentration polarization

    NASA Astrophysics Data System (ADS)

    Abu-Rjal, Ramadan; Rubinstein, Isaak; Zaltzman, Boris

    2016-06-01

    Until recently, based on the analysis pertaining to a perfectly charge selective interface, electro-convective instability in concentration polarization was attributed to the nonequilibrium mechanism related to the extended space charge which forms next to that of the electric double layer near the limiting current. More recently it was shown that imperfect charge selectivity of the interface makes equilibrium instability possible, driven by either equilibrium electro-osmosis or bulk electro-convection, or both. In this paper we identify and analyze the major surface and bulk factors affecting the electro-convective instability. These factors, some known previously under the names of diffusio-osmosis, electro-osmosis, or bulk electro-convection, and some newly identified in this paper are manifestations of the electric force and pressure gradient, balanced by the viscous force acting in various locations in solution. The contribution of these factors to hydrodynamic stability in concentration polarization is analyzed for a varying charge selectivity of the interface.

  2. Experimental Study of Parametric Subharmonic Instability in Stratified Fluids

    NASA Astrophysics Data System (ADS)

    Bourget, Baptiste; Joubaud, Sylvain; Odier, Philippe; Dauxois, Thierry

    2012-11-01

    Internal waves are believed to be of primary importance as they affect ocean mixing and energy transport. Several processes can lead to the breaking of internal waves and they usually involve non linear interactions between waves. In this work, we study experimentally the Parametric Subharmonic Instability, which provides an efficient mechanism to transfer energy from large to smaller scales. It consists in the destabilization of a primary wave and the spontaneous emission of two secondary waves, of lower frequencies and different wave vectors. We observe that the instability displays a different behavior if the primary wave is a monochromatic vertical mode-1 or a plane wave. Moreover, using a time-frequency analysis, we are able to observe the time evolution of the secondary frequencies. Using a Hilbert transform method we measure the different wave vectors and compare with theoretical predictions. As will be shown further, this instability plays a role in the mixing processes of stratified fluids (see abstract from P. Odier).

  3. LINEAR ELECTROSTATIC INSTABILITY OF THE ELECTRON BEAM ION SOURCE

    SciTech Connect

    Litwin, C.; Vella, M.C.; Sessler, A.

    1981-12-01

    Linear plasma fluid theory is used to study the stability of a cold electron beam in Brillouin equilibrium which passes through a stationary cold ion background, with particular interest in stability for parameters relevant to EBIS devices. Dispersion is studied both analytically and numerically. For {ell}=0, the usual infinite medium two stream instability condition is shown to correspond to a requirement that beam perveance exceed a minimum value, P>33 {micro}pervs; hence, this mode is stable for EBIS (P {approx} l{micro}perv). The Brillouin equilibrium rotation is shown to cause an electron-ion rotating stream instability, which is convectively unstable. The {ell}=1 mode is also found to be unstable. Higher modes numbers, {ell}>1, are unstable, but have reduced growth. Instability is only weakly affected by finite beam radius and boundary conditions.

  4. Numerical simulation of the hydrodynamic instability experiments and flow mixing

    NASA Astrophysics Data System (ADS)

    Bai, Jingsong; Wang, Tao; Li, Ping; Zou, Liyong; Liu, Cangli

    2009-12-01

    Based on the numerical methods of volume of fluid (VOF) and piecewise parabolic method (PPM) and parallel circumstance of Message Passing Interface (MPI), a parallel multi-viscosity-fluid hydrodynamic code MVPPM (Multi-Viscosity-Fluid Piecewise Parabolic Method) is developed and performed to study the hydrodynamic instability and flow mixing. Firstly, the MVPPM code is verified and validated by simulating three instability cases: The first one is a Riemann problem of viscous flow on the shock tube; the second one is the hydrodynamic instability and mixing of gaseous flows under re-shocks; the third one is a half height experiment of interfacial instability, which is conducted on the AWE’s shock tube. By comparing the numerical results with experimental data, good agreement is achieved. Then the MVPPM code is applied to simulate the two cases of the interfacial instabilities of jelly models accelerated by explosion products of a gaseous explosive mixture (GEM), which are adopted in our experiments. The first is implosive dynamic interfacial instability of cylindrical symmetry and mixing. The evolving process of inner and outer interfaces, and the late distribution of mixing mass caused by Rayleigh-Taylor (RT) instability in the center of different radius are given. The second is jelly layer experiment which is initialized with one periodic perturbation with different amplitude and wave length. It reveals the complex processes of evolution of interface, and presents the displacement of front face of jelly layer, bubble head and top of spike relative to initial equilibrium position vs. time. The numerical results are in excellent agreement with that experimental images, and show that the amplitude of initial perturbations affects the evolvement of fluid mixing zone (FMZ) growth rate extremely, especially at late times.

  5. Blast-Wave-Driven Instability Experiments Relevant To Supernova Hydrodynamics

    NASA Astrophysics Data System (ADS)

    Kuranz, Carolyn; Drake, R.; Grosskopf, M.; Budde, A.; Remington, B.; Robey, H.; Arnett, D.; Meakin, C.; Plewa, T.

    2011-05-01

    This presentation discusses experiments scaled to the blast wave driven instabilities at the He/H interface during the explosion phase of SN1987A. This core-collapse supernova was detected about 50 kpc from Earth making it the first supernova observed so closely to earth in modern times. The progenitor star was a blue supergiant with a mass of 18-20 solar masses. A blast wave occurred following the supernova explosion because there was a sudden, finite release of energy. Blast waves consist of a shock front followed by a rarefaction wave. When a blast wave crosses an interface with a decrease in density, hydrodynamic instabilities will develop. These experiments include target materials scaled in density to the He/H layer in SN1987A. About 5 kJ of laser energy from the Omega Laser facility irradiates a 150 µm plastic layer that is followed by a low-density foam layer. A blast wave structure similar to those in supernovae is created in the plastic layer. The blast wave crosses an interface with a drop in density and a precision-machined interface with multiple modes. The specific modal structure is based on simulation results of the evolution of the progenitor star. This produces unstable growth dominated by the Rayleigh-Taylor (RT) instability. We have detected the interface structure under these conditions, using dual orthogonal radiography, and will show some of the resulting data. This work is funded by the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, grant number DE-FG52-09NA29548, and by the National Laser User Facility Program, grant number DE-FG52-09NA29034.

  6. Maladaptive Plasticity for Motor Recovery after Stroke: Mechanisms and Approaches

    PubMed Central

    Takeuchi, Naoyuki; Izumi, Shin-Ichi

    2012-01-01

    Many studies in human and animal models have shown that neural plasticity compensates for the loss of motor function after stroke. However, neural plasticity concerning compensatory movement, activated ipsilateral motor projections and competitive interaction after stroke contributes to maladaptive plasticity, which negatively affects motor recovery. Compensatory movement on the less-affected side helps to perform self-sustaining activity but also creates an inappropriate movement pattern and ultimately limits the normal motor pattern. The activated ipsilateral motor projections after stroke are unable to sufficiently support the disruption of the corticospinal motor projections and induce the abnormal movement linked to poor motor ability. The competitive interaction between both hemispheres induces abnormal interhemispheric inhibition that weakens motor function in stroke patients. Moreover, widespread disinhibition increases the risk of competitive interaction between the hand and the proximal arm, which results in an incomplete motor recovery. To minimize this maladaptive plasticity, rehabilitation programs should be selected according to the motor impairment of stroke patients. Noninvasive brain stimulation might also be useful for correcting maladaptive plasticity after stroke. Here, we review the underlying mechanisms of maladaptive plasticity after stroke and propose rehabilitation approaches for appropriate cortical reorganization. PMID:22792492

  7. Continuum modeling of plastic flow localization in irradiated fcc metals

    NASA Astrophysics Data System (ADS)

    Po, Giacomo; Ghoniem, Nasr

    2013-11-01

    Under mechanical loading, neutron or ion irradiated metals may develop a mechanical instability characterized by the localization of plastic flow in narrow channels that are cleared of irradiation-induced defects. The resulting highly heterogeneous deformation can play a significant role in crack nucleation, fracture propagation, and premature failure of structural components used in nuclear applications. In this work, we develop a two-dimensional continuum model of plastic flow localization based on the continuum theory of dislocations. This framework allows a mechanism-based description of deformation in which plastic distortion is directly calculated from the evolution of dislocation density tensor fields on each slip system. The dislocation densities mutually interact through the self-consistent stress field derived from the deformation gradient and through back and flow stress corrections. The interaction between dislocation fields and irradiation-induced defects (mainly stacking fault tetrahedra (SFTs) in fcc metals) is twofold. First, the flow stress depends locally on the SFT density. Second, and based on existing molecular dynamics (MD) simulation results, dislocation fluxes are included as sink terms in the evolution equation of the SFT density. The model is implemented numerically using the finite element method (FEM) and simulation results for simple shear loading are presented. It is demonstrated here that small spatial fluctuations in the density of SFTs, coupled with their destruction by dislocation interaction, leads to plastic flow localization.

  8. Collective instability of micro- and nanoscale structures

    NASA Astrophysics Data System (ADS)

    Chen, Ziguang

    Engineering objects or systems with a very small size in dimension can have strikingly different mechanical properties from their bulk counterparts found in our everyday lives. Furthermore, when the spacing or distance among these small structures is also small, weak interactions that are usually ignored can play an important role. For these reasons, collective behaviors or properties of small structures are considered in this thesis. The bulk of this thesis is devoted to the exploration of new ways to analyze the collective instability in nanometer and micrometer scale structures, including beams, columns, and spheres. At such a scale, it can be shown that the surrounding media brings about significant effects. For instance, the deformation of one object could trigger the deformation of the media, which further affects the other neighboring objects; nontrivial forces between closely spaced bodies, e.g., van der Waals, lead to exotic dynamic behaviors to the final assembly. Chapter 1 provides a general background on instability studies in nanometer and micrometer scale structures. Chapter 2 gives examples on how to analyze collective buckling of a two-dimensional array of nanoscale columns with their lower ends built into an elastic substrate. From this, the model was extended into a molecular type of multi-stacks or lamellae to explain the findings of a two dimensional (2D) hierarchical buckling. In Chapter 3, further consideration was given to the elastic deformation in the small objects instead of simply treating them as rigid ones in Chapter 2. Following these theoretical analyses, Chapter 4-6 investigates the assembly of sphere-like particles, including the mechanical property of particle-fibers as well as the buckling of particle-composed bi-layers. The final Chapter lays out theoretical questions and directions that can be used for future research. It is the hope that presenting this thesis partially fills a knowledge gap concerning the instability or

  9. The effects of control field detuning on the modulation instability in a three-level quantum well system

    NASA Astrophysics Data System (ADS)

    Borgohain, Nitu; Konar, S.

    2016-06-01

    The paper presents a theoretical study of the modulation instability of a continuous or quasi-continuous optical probe in a three level quantum well system under electromagnetically induced transparency. The modulation instability is affected by the control field detuning, as well as even-order dispersion and by the strength of Kerr (third-order) and quintic (fifth-order) nonlinearities. The fourth-order dispersion reduces the bandwidth over which modulation instability occurs, whereas the quintic nonlinearity saturates the growth of the modulation instability. Detuning the control field from resonance can significantly reduce the growth of the modulation instability at both low and high power levels. At low powers, the system becomes stable against modulation instability for small detuning of the control field and at high powers modulation instability disappears for larger detuning.

  10. Observation and Analysis of Resistive Instabilities in Negative Central Shear in DIII-D Discharges with L-Mode Edge

    SciTech Connect

    Jayakumar, R.J.; Austin, M.E.; Brennan, D.P.; Chu, M.S.; Luce, T.C.; Strait, E.J.; Turnbull, A.D.

    2002-07-01

    In DIII-D plasmas with L-mode edge and negative central shear (q{sub axis}-q{sub min} {approx}0.3 to 0.5), an interchange-like instability has been observed [1]. The instability and a subsequent tearing mode cause reduction of the core electron temperature and plasma rotation, and therefore the instability affects discharge evolution and the desired high performance is not achieved. Stability analyses indicate robust ideal stability, while the Resistive Interchange Mode criterion is marginal and the instability appears to be localized initially. Based on this, we believe that the mode is, most likely, a Resistive Interchange Mode. The amplitude of the instability is correlated with the location of the q{sub min} surface and inversely with the fast-ion pressure. There is indication that the interchange-like instability may be ''seeding'' the tearing mode that sometimes follows the interchange-like instability.

  11. Neuromodulation of associative and organizational plasticity across the life span: empirical evidence and neurocomputational modeling.

    PubMed

    Li, Shu-Chen; Brehmer, Yvonne; Shing, Yee Lee; Werkle-Bergner, Markus; Lindenberger, Ulman

    2006-01-01

    Developmental plasticity is the key mechanism that allows humans and other organisms to modify and adapt to contextual and experiential influences. Thus, reciprocal co-constructive interactions between behavioral and neuronal plasticity play important roles in regulating neurobehavioral development across the life span. This review focuses on behavioral and neuronal evidence of lifespan differences in associative memory plasticity and plasticity of the functional organization of cognitive and cortical processes, as well as the role of the dopaminergic system in modulating such plasticity. Special attention is given to neurocomputational models that help exploring lifespan differences in neuromodulation of neuronal and behavioral plasticity. Simulation results from these models suggest that lifespan changes in the efficacy of neuromodulatory mechanisms may shape associative memory plasticity and the functional organization of neurocognitive processes by affecting the fidelity of neuronal signal transmission, which has consequences for the distinctiveness of neurocognitive representations and the efficacy of distributed neural coding. PMID:16930705

  12. Fast Transverse Instability and Electron Cloud Measurements in Fermilab Recycler

    SciTech Connect

    Eldred, Jeffery; Adamson, Philip; Capista, David; Eddy, Nathan; Kourbanis, Ioanis; Morris, Denton; Thangaraj, Jayakar; Yang, Ming-Jen; Zwaska, Robert; Ji, Yichen

    2015-03-01

    A new transverse instability is observed that may limit the proton intensity in the Fermilab Recycler. The instability is fast, leading to a beam-abort loss within two hundred turns. The instability primarily affects the first high-intensity batch from the Fermilab Booster in each Recycler cycle. This paper analyzes the dynamical features of the destabilized beam. The instability excites a horizontal betatron oscillation which couples into the vertical motion and also causes transverse emittance growth. This paper describes the feasibility of electron cloud as the mechanism for this instability and presents the first measurements of the electron cloud in the Fermilab Recycler. Direct measurements of the electron cloud are made using a retarding field analyzer (RFA) newly installed in the Fermilab Recycler. Indirect measurements of the electron cloud are made by propagating a microwave carrier signal through the beampipe and analyzing the phase modulation of the signal. The maximum betatron amplitude growth and the maximum electron cloud signal occur during minimums of the bunch length oscillation.

  13. Interfacial Instability during Granular Erosion

    NASA Astrophysics Data System (ADS)

    Lefebvre, Gautier; Merceron, Aymeric; Jop, Pierre

    2016-02-01

    The complex interplay between the topography and the erosion and deposition phenomena is a key feature to model granular flows such as landslides. Here, we investigated the instability that develops during the erosion of a wet granular pile by a dry dense granular flow. The morphology and the propagation of the generated steps are analyzed in relation to the specific erosion mechanism. The selected flowing angle of the confined flow on a dry heap appears to play an important role both in the final state of the experiment, and for the shape of the structures. We show that the development of the instability is governed by the inertia of the flow through the Froude number. We model this instability and predict growth rates that are in agreement with the experiment results.

  14. Interfacial instabilities and Kapitsa pendula

    NASA Astrophysics Data System (ADS)

    Krieger, Madison

    2015-11-01

    Determining the critera for onset and amplitude growth of instabilities is one of the central problems of fluid mechanics. We develop a parallel between the Kapitsa effect, in which a pendulum subject to high-frequency low-amplitude vibrations becomes stable in the inverted position, and interfaces separating fluids of different density. It has long been known that such interfaces can be stabilized by vibrations, even when the denser fluid is on top. We demonstrate that the stability diagram for these fluid interfaces is identical to the stability diagram for an appopriate Kapitsa pendulum. We expand the robust, ``dictionary''-type relationship between Kapitsa pendula and interfacial instabilities by considering the classical Rayleigh-Taylor, Kelvin-Helmholtz and Plateau instabilities, as well as less-canonical examples ranging in scale from the micron to the width of a galaxy.

  15. Interfacial Instability during Granular Erosion.

    PubMed

    Lefebvre, Gautier; Merceron, Aymeric; Jop, Pierre

    2016-02-12

    The complex interplay between the topography and the erosion and deposition phenomena is a key feature to model granular flows such as landslides. Here, we investigated the instability that develops during the erosion of a wet granular pile by a dry dense granular flow. The morphology and the propagation of the generated steps are analyzed in relation to the specific erosion mechanism. The selected flowing angle of the confined flow on a dry heap appears to play an important role both in the final state of the experiment, and for the shape of the structures. We show that the development of the instability is governed by the inertia of the flow through the Froude number. We model this instability and predict growth rates that are in agreement with the experiment results. PMID:26919014

  16. Instability of EDS maglev systems

    SciTech Connect

    Cai, Y.; Chen, S.S.

    1993-09-01

    Instabilities of an EDS maglev suspension system with 3 D.O.F. and 5 D.O.F. vehicles traveling on a double L-shaped set of guideway conductors have been investigated with various experimentally measured magnetical force data incorporated into the theoretical models. Divergence and flutter are obtained from both analytical and numerical solutions for coupled vibration of the 3 D.O.F. maglev vehicle model. Instabilities of five direction motions (heave, slip, rill, pitch and yaw) are observed for the 4 D.O.F. vehicle model. It demonstrates that system parameters, such as, system damping, vehicle geometry and coupling effects among five different motions play very important roles in the occurrence of dynamic instabilities of maglev vehicles.

  17. Faraday instability in deformable domains

    NASA Astrophysics Data System (ADS)

    Pucci, Giuseppe; Ben Amar, Martine; Couder, Yves

    2014-11-01

    We investigate the Faraday instability in floating liquid lenses, as an example of hydrodynamic instability that develops in a domain with flexible boundaries. We show that a mutual adaptation of the instability pattern and the domain shape occurs, as a result of the competition between the wave radiation pressure and the capillary response of the lens border. Two archetypes of behaviour are observed. In the first, stable shapes are obtained experimentally and predicted theoretically as the exact solutions of a Riccati equation, and they result from the equilibrium between wave radiation pressure and capillarity. In the second, the radiation pressure exceeds the capillary response of the lens border and leads to non-equilibrium behaviours, with breaking into smaller domains that have a complex dynamics including spontaneous propagation. The authors are grateful to Université Franco-Italienne (UFI) for financial support.

  18. A Plasma, Magnetorotational Instability Experiment

    NASA Astrophysics Data System (ADS)

    Collins, C.; Forest, C. B.; Kendrick, R.; Seltzman, A.

    2007-11-01

    A new experiment is underway at the University of Wisconsin to investigate the magnetorotational instability in a plasma. Magnetorotational instability (MRI) is a likely mechanism that could account for the observed accretion rates in astrophysical objects. The instability occurs when a weak magnetic field is present, so that tension in perturbed field lines transfers angular momentum outward while mass moves towards the center. In the Plasma Dynamo Experiment Prototype, a cylindrical, axisymmetric, ring cusp confinement geometry is used to produce a large unmagnetized plasma, confined by a highly localized magnetic field at the plasma boundary. The plasma is stirred by a novel axisymmetric electrode set that can control the rotation (angular momentum profile). The feasibility of observing the MRI will be discussed and initial results from a protoype experiment will be presented.

  19. Hydrodynamick instabilities on ICF capsules

    SciTech Connect

    Haan, S.W.

    1991-06-07

    This article summarizes our current understanding of hydrodynamic instabilities as relevant to ICF. First we discuss classical, single mode Rayleigh-Taylor instability, and nonlinear effects in the evolution of a single mode. Then we discuss multimode systems, considering: (1) the onset of nonlinearity; (2) a second order mode coupling theory for weakly nonlinear effects, and (3) the fully nonlinear regime. Two stabilization mechanisms relevant to ICF are described next: gradient scale length and convective stabilization. Then we describe a model which is meant to estimate the weakly nonlinear evolution of multi-mode systems as relevant to ICF, given the short-wavelength stabilization. Finally, we discuss the relevant code simulation capability, and experiments. At this time we are quite optimistic about our ability to estimate instability growth on ICF capsules, but further experiments and simulations are needed to verify the modeling. 52 refs.

  20. Performance through Deformation and Instability

    NASA Astrophysics Data System (ADS)

    Bertoldi, Katia

    2015-03-01

    Materials capable of undergoing large deformations like elastomers and gels are ubiquitous in daily life and nature. An exciting field of engineering is emerging that uses these compliant materials to design active devices, such as actuators, adaptive optical systems and self-regulating fluidics. Compliant structures may significantly change their architecture in response to diverse stimuli. When excessive deformation is applied, they may eventually become unstable. Traditionally, mechanical instabilities have been viewed as an inconvenience, with research focusing on how to avoid them. Here, I will demonstrate that these instabilities can be exploited to design materials with novel, switchable functionalities. The abrupt changes introduced into the architecture of soft materials by instabilities will be used to change their shape in a sudden, but controlled manner. Possible and exciting applications include materials with unusual properties such negative Poisson's ratio, phononic crystals with tunable low-frequency acoustic band gaps and reversible encapsulation systems.

  1. Microsatellite instability in bladder cancer.

    PubMed

    Gonzalez-Zulueta, M; Ruppert, J M; Tokino, K; Tsai, Y C; Spruck, C H; Miyao, N; Nichols, P W; Hermann, G G; Horn, T; Steven, K

    1993-12-01

    Somatic instability at microsatellite repeats was detected in 6 of 200 transitional cell carcinomas of the bladder. Instabilities were apparent as changes in (GT)n repeat lengths on human chromosome 9 for four tumors and as alterations in a (CAG)n repeat in the androgen receptor gene on the X chromosome for three tumors. Single locus alterations were detected in three tumors, while three other tumors revealed changes in two or more loci. In one tumor we found microsatellite instability in all five loci analyzed on chromosome 9. The alterations detected were either minor 2-base pair changes or larger (> 2 base pairs) alterations in repeat length. All six tumors were low stage (Ta-T1), suggesting that these alterations can occur early in bladder tumorigenesis. PMID:8242615

  2. SURGICAL TREATMENT OF PATELLOFEMORAL INSTABILITY

    PubMed Central

    de Andrade, Marco Antônio Percope; de Abreu e Silva, Guilherme Moreira; Freire, Marcelo Machado; Teixeira, Luiz Eduardo Moreira

    2015-01-01

    Objective: To describe functional outcomes following surgical treatment of patients with patellofemoral instability submitted to patellar realignment. Methods: This was a retrospective study evaluating 34 operated knees for patellofemoral instability between 1989 and 2004. The patients were evaluated in the late postoperative period when a functional questionnaire was applied. Results: After a mean follow-up time of 6 years and 5 months, the mean score was 82.94 in the surgical group (p=0.00037). The results of this investigation showed pain relief in 97.05% and low rate of recurrent dislocation (5.88%), although lower scores were seen in intense articular activities (squatting, running and jumping). No patient developed osteoarthritis while being followed up. Conclusion: The procedure for joint described in this paper was shown to be effective for treating patients with recurrent patellofemoral instability. PMID:27077065

  3. Stellar explosions, instabilities, and turbulence

    SciTech Connect

    Drake, R. P.; Kuranz, C. C.; Miles, A. R.; Muthsam, H. J.; Plewa, T.

    2009-04-15

    It has become very clear that the evolution of structure during supernovae is centrally dependent on the pre-existing structure in the star. Modeling of the pre-existing structure has advanced significantly, leading to improved understanding and to a physically based assessment of the structure that will be present when a star explodes. It remains an open question whether low-mode asymmetries in the explosion process can produce the observed effects or whether the explosion mechanism somehow produces jets of material. In any event, the workhorse processes that produce structure in an exploding star are blast-wave driven instabilities. Laboratory experiments have explored these blast-wave-driven instabilities and specifically their dependence on initial conditions. Theoretical work has shown that the relative importance of Richtmyer-Meshkov and Rayleigh-Taylor instabilities varies with the initial conditions and does so in ways that can make sense of a range of astrophysical observations.

  4. Development of Methods of Characterizing Coal in Its Plastic State

    NASA Technical Reports Server (NTRS)

    Lloyd, W. G.

    1978-01-01

    Coal in its plastic state (typically 400-460 C) was examined by the isothermal Gieseler plastometry of seven selected coals of widely varying plastic properties. Kinetic models were proposed for the isothermal plastometric curves. Plastic behavior was compared with a variety of laboratory analyses and characterizations of these coals, including classical coal analysis; mineral analysis; microstructural analysis (extractable fractions, surface area measurement, and petrographic analysis); and thermal analysis (thermogravimetric analysis, thermomechanical analysis, and differential scanning calorimetry). The phenomenon of a sharp, large, poorly reproducible exotherm in the differential scanning calorimetric analysis of coking coals was examined. Several coal extrudates show mineral distribution, organic maceral composition and overall calorific value to be little affected by 800 F extrusion. Volatile matter and plastic properties are moderately reduced, and the network structure (as gauged by extractables) appears to be slightly degraded in the extrusion process.

  5. Modulation of Synaptic Plasticity by Glutamatergic Gliotransmission: A Modeling Study

    PubMed Central

    De Pittà, Maurizio; Brunel, Nicolas

    2016-01-01

    Glutamatergic gliotransmission, that is, the release of glutamate from perisynaptic astrocyte processes in an activity-dependent manner, has emerged as a potentially crucial signaling pathway for regulation of synaptic plasticity, yet its modes of expression and function in vivo remain unclear. Here, we focus on two experimentally well-identified gliotransmitter pathways, (i) modulations of synaptic release and (ii) postsynaptic slow inward currents mediated by glutamate released from astrocytes, and investigate their possible functional relevance on synaptic plasticity in a biophysical model of an astrocyte-regulated synapse. Our model predicts that both pathways could profoundly affect both short- and long-term plasticity. In particular, activity-dependent glutamate release from astrocytes could dramatically change spike-timing-dependent plasticity, turning potentiation into depression (and vice versa) for the same induction protocol. PMID:27195153

  6. Lithospheric Architecture, Heterogenities, Instabilities, Melting - insight form numerical modelling

    NASA Astrophysics Data System (ADS)

    Gorczyk, Weronika; Hobbs, Bruce; Ord, Alison; Gessner, Klaus; Gerya, Taras V.

    2010-05-01

    The seismological structure of the Earth's lithosphere is identified to be strongly heterogeneous in terms of thermal and rheological structures. Lithospheric discontinuities (sharp changes in the thermal and/or compositional structure) are thought to be long lived and are mostly correlated with major tectonic boundaries that commonly have been reactivated and which subsequently are the foci of magma intrusion and major mineralization. Resent studies have shown that mantle metasomatism is also controlled by such boundaries. This paper explores the control that lithospheric heterogeneity exerts on the thermal and chemical evolution during deformation subsequent to the development of the heterogeneity. We explore the behaviour of the rheological heterogeneous lithosphere in a compressional regime. The occurrence of such variations may be caused for instance by amalgamation of micro-continents such as is thought to be characteristic of the Yilgarn, Western Australia or South Africa. Theses micro-continents, due to diverse histories may be characterised by various thermal and rheological structures. The models are simplistic but illustrate the basic principles. The code used in this study is based on a conservative finite-difference, multi-grid, marker in cell method. Devolatilisation reactions and melting can affect the physical properties of rocks and are incorporated in a self-consistent manner. We use a petrological-thermomechanical modelling approach with all rock properties including mechanical properties calculated in the Lagrangian scheme for rock markers at every time step based on Gibbs free energy minimization as a function of the local pressure, temperature and rock composition. The results illustrate that initial structural complexity is necessary for and has a dramatic effect on fault and development, the growth of deep basins, core complex formation, melting and devolatilisation within the lithosphere. The horizontal and vertical variation in plastic

  7. Plastics recycling: challenges and opportunities

    PubMed Central

    Hopewell, Jefferson; Dvorak, Robert; Kosior, Edward

    2009-01-01

    Plastics are inexpensive, lightweight and durable materials, which can readily be moulded into a variety of products that find use in a wide range of applications. As a consequence, the production of plastics has increased markedly over the last 60 years. However, current levels of their usage and disposal generate several environmental problems. Around 4 per cent of world oil and gas production, a non-renewable resource, is used as feedstock for plastics and a further 3–4% is expended to provide energy for their manufacture. A major portion of plastic produced each year is used to make disposable items of packaging or other short-lived products that are discarded within a year of manufacture. These two observations alone indicate that our current use of plastics is not sustainable. In addition, because of the durability of the polymers involved, substantial quantities of discarded end-of-life plastics are accumulating as debris in landfills and in natural habitats worldwide. Recycling is one of the most important actions currently available to reduce these impacts and represents one of the most dynamic areas in the plastics industry today. Recycling provides opportunities to reduce oil usage, carbon dioxide emissions and the quantities of waste requiring disposal. Here, we briefly set recycling into context against other waste-reduction strategies, namely reduction in material use through downgauging or product reuse, the use of alternative biodegradable materials and energy recovery as fuel. While plastics have been recycled since the 1970s, the quantities that are recycled vary geographically, according to plastic type and application. Recycling of packaging materials has seen rapid expansion over the last decades in a number of countries. Advances in technologies and systems for the collection, sorting and reprocessing of recyclable plastics are creating new opportunities for recycling, and with the combined actions of the public, industry and governments it

  8. Plastics recycling: challenges and opportunities.

    PubMed

    Hopewell, Jefferson; Dvorak, Robert; Kosior, Edward

    2009-07-27

    Plastics are inexpensive, lightweight and durable materials, which can readily be moulded into a variety of products that find use in a wide range of applications. As a consequence, the production of plastics has increased markedly over the last 60 years. However, current levels of their usage and disposal generate several environmental problems. Around 4 per cent of world oil and gas production, a non-renewable resource, is used as feedstock for plastics and a further 3-4% is expended to provide energy for their manufacture. A major portion of plastic produced each year is used to make disposable items of packaging or other short-lived products that are discarded within a year of manufacture. These two observations alone indicate that our current use of plastics is not sustainable. In addition, because of the durability of the polymers involved, substantial quantities of discarded end-of-life plastics are accumulating as debris in landfills and in natural habitats worldwide. Recycling is one of the most important actions currently available to reduce these impacts and represents one of the most dynamic areas in the plastics industry today. Recycling provides opportunities to reduce oil usage, carbon dioxide emissions and the quantities of waste requiring disposal. Here, we briefly set recycling into context against other waste-reduction strategies, namely reduction in material use through downgauging or product reuse, the use of alternative biodegradable materials and energy recovery as fuel. While plastics have been recycled since the 1970s, the quantities that are recycled vary geographically, according to plastic type and application. Recycling of packaging materials has seen rapid expansion over the last decades in a number of countries. Advances in technologies and systems for the collection, sorting and reprocessing of recyclable plastics are creating new opportunities for recycling, and with the combined actions of the public, industry and governments it

  9. Effects of incoming wind condition and wind turbine aerodynamics on the hub vortex instability

    NASA Astrophysics Data System (ADS)

    Ashton, R.; Viola, F.; Gallaire, F.; Iungo, G. V.

    2015-06-01

    Dynamics and instabilities occurring in the near-wake of wind turbines have a crucial role for the wake downstream evolution, and for the onset of far-wake instabilities. Furthermore, wake dynamics significantly affect the intra-wind farm wake flow, wake interactions and potential power losses. Therefore, the physical understanding and predictability of wind turbine wake instabilities become a nodal point for prediction of wind power harvesting and optimization of wind farm layout. This study is focused on the prediction of the hub vortex instability encountered within wind turbine wakes under different operational conditions of the wind turbine. Linear stability analysis of the wake flow is performed by means of a novel approach that enables to take effects of turbulence on wake instabilities into account. Stability analysis is performed by using as base flow the time-averaged wake velocity field at a specific downstream location. The latter is modeled through Carton-McWilliams velocity profiles by mimicking the presence of the hub vortex and helicoidal tip vortices, and matching the wind turbine thrust coefficient predicted through the actuator disc model. The results show that hub vortex instability is promoted by increasing the turbine thrust coefficient. Indeed, a larger aerodynamic load produces an enhanced wake velocity deficit and axial shear, which are considered the main sources for the wake instability. Nonetheless, wake swirl also promotes hub vortex instability, and it can also affect the azimuthal wavenumber of the most unstable mode.

  10. Beam instabilities in hadron synchrotrons

    DOE PAGESBeta

    Metral, E.; T. Argyropoulos; Bartosik, H.; Biancacci, N.; Buffat, X.; Esteban Muller, J. F.; Herr, W.; Iadarola, G.; Lasheen, A.; Li, K.; et al

    2016-04-01

    Beam instabilities cover a wide range of effects in particle accelerators and they have been the subjects of intense research for several decades. As the machines performance was pushed new mechanisms were revealed and nowadays the challenge consists in studying the interplays between all these intricate phenomena, as it is very often not possible to treat the different effects separately. Furthermore, the aim of this paper is to review the main mechanisms, discussing in particular the recent developments of beam instability theories and simulations.

  11. Active suppression of compressor instabilities

    NASA Technical Reports Server (NTRS)

    Epstein, A. H.; Ffowcs Williams, J. E.; Greitzer, E. M.

    1986-01-01

    A strategy is proposed for controlling aerodynamic instabilities which limit the useful range of both axial and centrifugal turbomachines. Both local and global instabilities (incipient rotating stall and surge) are analyzed. A theory is developed which shows how an additional disturbance, driven from real time data measured within the machine, can be generated so as to realize a device with characteristics fundamentally different from those of the turbomachine without control; for the particular compressor analyzed, the control led to a 20 percent increase in the extent of the stable operating range. The use of structural dynamics to enhance stability is also discussed.

  12. Hydrodynamic instability and mix experiments at National Ignition Facility

    NASA Astrophysics Data System (ADS)

    Smalyuk, Vladimir

    2013-10-01

    Hydrodynamic growth and its effects on implosion performance and mix are being studied in hohlraum-driven implosions using gas-filled plastic shells at the National Ignition Facility (NIF). These experiments are motivated by observed elevated amounts of plastic mixed into the hot spot, degrading the performance of high-compression cryogenic DT layered implosions on NIF. Spherical shells with pre-imposed 2D modulations are being developed to measure Rayleigh-Taylor (RT) instability growth in the acceleration phase of implosions using in-flight x-ray radiography. Ablation-front RT growth measurements will be carried out for mode numbers ranging from 30 to 80 at drive conditions relevant to high-compression cryogenic implosions. In addition, implosion performance and mix are being studied at peak compression using plastic ``Symcap'' shells filled with tritium gas and imbedding localized CD diagnostic layer in various locations in the ablator. Neutron yield and ion temperature of the DT fusion reactions are used as a measure of shell-gas mix, while neutron yield of the TT fusion reaction is used as a measure of implosion performance. Experimental results and comparisons with 1D and 2D simulations, including mix models, will be presented. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344.

  13. Posterior instability caused by batter's shoulder.

    PubMed

    Kang, Richard W; Mahony, Gregory T; Harris, Thomas C; Dines, Joshua S

    2013-10-01

    In summary, batter’s shoulder is a rare and only recently recognized entity. This condition is posterior shoulder instability caused by a missed attempt at hitting a pitch, especially with an outside pitch. The lack of counterforce from hitting a ball produces increased forces imparted on the posterior capsulolabral complex of the lead shoulder during batting. If the player fails conservative management, she or he can undergo an arthroscopic posterior labral repair instead of debridement. After treatment, the player can expect to return to play after approximately 6 to 7 months. Initial results from a small, retrospective series demonstrate greater than 90% excellent results. These findings are similar to current literature for arthroscopic treatment of posterior instability, which reports success rates that range from 75% to 91%. Longer-term follow-up will be needed to determine the natural history and prognosis or batter’s shoulder. Based on initial results, the authors predict good to excellent results for most players with batter’s shoulder who undergo proper treatment. Additionally, with the exception of switch hitters, the nonthrowing arm is affected. This can also improve the athlete’s return to play. PMID:24079435

  14. Bounds on Transient Instability for Complex Ecosystems.

    PubMed

    Caravelli, Francesco; Staniczenko, Phillip P A

    2016-01-01

    Stability is a desirable property of complex ecosystems. If a community of interacting species is at a stable equilibrium point then it is able to withstand small perturbations to component species' abundances without suffering adverse effects. In ecology, the Jacobian matrix evaluated at an equilibrium point is known as the community matrix, which describes the population dynamics of interacting species. A system's asymptotic short- and long-term behaviour can be determined from eigenvalues derived from the community matrix. Here we use results from the theory of pseudospectra to describe intermediate, transient dynamics. We first recover the established result that the transition from stable to unstable dynamics includes a region of 'transient instability', where the effect of a small perturbation to species' abundances-to the population vector-is amplified before ultimately decaying. Then we show that the shift from stability to transient instability can be affected by uncertainty in, or small changes to, entries in the community matrix, and determine lower and upper bounds to the maximum amplitude of perturbations to the population vector. Of five different types of community matrix, we find that amplification is least severe when predator-prey interactions dominate. This analysis is relevant to other systems whose dynamics can be expressed in terms of the Jacobian matrix. PMID:27327511

  15. Plastics & Composites Technology Needs Assessment.

    ERIC Educational Resources Information Center

    Oakland Community Coll., Farmington, MI. Office of Institutional Planning and Analysis.

    In 1991, a study was conducted by Oakland Community College (OCC) to evaluate the need for a proposed plastics and composites technology program for design engineers. General information was obtained through a literature search, from the Society of the Plastics Industry, Inc., the Michigan Employment Security Commission, and interviews with…

  16. Boron Doped Plastic Scintillator Efficiency

    NASA Astrophysics Data System (ADS)

    Mahl, Adam; Chouinard-Dussault, Pascale; Pecinovsky, Cory; Potter, Andrew; Remedes, Tyler; Dorgan, John; Greife, Uwe

    2013-04-01

    This talk will describe the progress made in an interdisciplinary development project aimed at cost-effective, neutron sensitive, plastic scintillator. Colorado School of Mines researchers with backgrounds in Physics, Chemistry, and Chemical Engineering have worked on the incorporation of ^10B in plastics through extrusion. First results on transparent samples using fluorescent spectroscopy and beta excitation will be presented.

  17. Plastics to fuel: A review

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This paper reviews recent developments in catalytic and non-catalytic degradation of waste plastics into fuels. Thermal degradation decomposes plastic into three fractions: gas, crude oil, and solid residue. Crude oil from non-catalytic pyrolysis is usually composed of higher boiling point hydrocarb...

  18. High-density implosion via suppression of Rayleigh–Taylor instability

    NASA Astrophysics Data System (ADS)

    Shiroto, Takashi; Ohnishi, Naofumi; Sunahara, Atsushi; Fujioka, Shinsuke; Sasaki, Akira

    2016-05-01

    Radiation hydrodynamic simulations of ICF capsules assuming a kJ-class laser facility were conducted to evaluate the hydrodynamic stability of a brominated plastic shell. An opacity table based on a detailed atomic model was employed so that more quantitative forecast of the implosion dynamics could be performed. A lightly doped shell could form a high-density core at the maximum compression by suppressing the hydrodynamic instability.

  19. Filamentation due to the Weibel Instability in two counterstreaming laser ablated plasmas

    NASA Astrophysics Data System (ADS)

    Dong, Quan-Li; Yuan, Dawei; Gao, Lan; Liu, Xun; Chen, Yangao; Jia, Qing; Hua, Neng; Qiao, Zhanfeng; Chen, Ming; Zhu, Baoqiang; Zhu, Jianqiang; Zhao, Gang; Ji, Hantao; Sheng, Zheng-Ming; Zhang, Jie

    2016-05-01

    Weibel-type filamentation instability was observed in the interaction of two counter streaming laser ablated plasma flows, which were supersonic, collisionless, and closely relevant to astrophysical conditions. The plasma flows were created by irradiating a pair of oppositely standing plastic (CH) foils with 1ns-pulsed laser beams of total energy of 1.7 kJ in two laser spots. With characteristics diagnosed in experiments, the calculated features of Weibel-type filaments are in good agreement with measurements.

  20. Imaging brain plasticity after trauma

    PubMed Central

    Kou, Zhifeng; Iraji, Armin

    2014-01-01

    The brain is highly plastic after stroke or epilepsy; however, there is a paucity of brain plasticity investigation after traumatic brain injury (TBI). This mini review summarizes the most recent evidence of brain plasticity in human TBI patients from the perspective of advanced magnetic resonance imaging. Similar to other forms of acquired brain injury, TBI patients also demonstrated both structural reorganization as well as functional compensation by the recruitment of other brain regions. However, the large scale brain network alterations after TBI are still unknown, and the field is still short of proper means on how to guide the choice of TBI rehabilitation or treatment plan to promote brain plasticity. The authors also point out the new direction of brain plasticity investigation. PMID:25206874

  1. Computational strain gradient crystal plasticity

    NASA Astrophysics Data System (ADS)

    Niordson, Christian F.; Kysar, Jeffrey W.

    2014-01-01

    A numerical method for viscous strain gradient crystal plasticity theory is presented, which incorporates both energetic and dissipative gradient effects. The underlying minimum principles are discussed as well as convergence properties of the proposed finite element procedure. Three problems of plane crystal plasticity are studied: pure shear of a single crystal between rigid platens as well as plastic deformation around cylindrical voids in hexagonal close packed and face centered cubic crystals. Effective in-plane constitutive slip parameters for plane strain deformation of specifically oriented face centered cubic crystals are developed in terms of the crystallographic slip parameters. The effect on geometrically necessary dislocation structures introduced by plastic deformation is investigated as a function of the ratio of void radius to plasticity length scale.

  2. Cervical ligamentous instability in a canine in vivo model.

    PubMed

    Whitehill, R; Moran, D J; Fechner, R E; Ruch, W W; Drucker, S; Hooper, W E; McCoig, J A

    1987-12-01

    A canine in vivo model of midcervical ligamentous instability was developed by dividing the anterior longitudinal ligament, anulus fibrosus, and all posterior ligamentous structures including the ligamentum flavum. The natural history of healing in the model, the effect on its healing by an adjacent one-level arthrodesis, and the effect of a one-level arthrodesis on normal adjacent ligamentous structures were studied radiographically, mechanically, and histologically. The authors determined that healing takes place primarily by anterior scar formation in their instability model but not to a degree sufficient to recreate normal mechanical stability. After three months, healing in the model was not affected by an adjacent arthrodesis; however, acutely, instability apparently was increased as three animals became quadriplegic between the second and fourth postoperative days. Arthrodesis did not affect adjacent normal ligamentous structures, during this period. Incomplete healing in the authors' model supports those who advocate arthrodesis as the treatment of choice for destabilizing cervical ligamentous injury. The authors previously reported the case of a patient who sustained bilateral facet dislocations adjacent to an arthrodesed segment and questioned whether this resulted from a stress-concentrating effect. This study indicates that this could well have been the case acutely. Thus, inadvertent exclusion of an unstable segment from an arthrodesis has potentially catastrophic results. Finally, the authors also have previously questioned whether arthrodesis of a midcervical segment could lead to instability of adjacent normal segments. This project does not support such a concern, at least for the three postoperative months of study. PMID:3441821

  3. [Neuropsychology, plasticity and childhood epilepsy].

    PubMed

    Lassonde, Maryse; Sauerwein, Hannelore C

    2007-11-01

    Epilepsy is one of the most frequent childhood disorders. While most cases are well controlled, approximately 30-50% are resistant to medical treatment. In these cases, neurosurgery may be an option. Since 1979, our team at the Sainte-Justine Hospital in Montreal has studied the impact of epilepsy on the psycho-motor and cognitive development of the affected children. The aim of a first series of studies was to explore the extent and limits of cerebral plasticity by investigating the neuropsychological sequelae of early versus late callosotomy and hemispherectomy. In keeping with the plasticity hypothesis, the results revealed that the children who were operated before puberty showed fewer deficits than those operated during adolescence or adulthood. However, the compensatory mechanisms available to them appeared to be limited with respect to the nature and complexity of the information they can process. For instance, young children having undergone section of the corpus callosum resembled individuals born without a corpus callosum (callosal agenesis) in that there did not show the typical disconnection deficits seen in adult ''split-brain'' patients. However, they exhibited deficits on tasks requiring interhemispheric integration of motor and visuo-motor information. By the same token, hemispherectomy patients were still able to make visual judgements in their ''blind'' visual field but they were found to be impaired on a variety of visual and auditory tasks (localization of a sound sources in space) requiring the participation of both hemispheres. In a second series of studies, carried out in collaboration with a Parisian team, we intended to describe the neuropsychological profile of focal epilepsies, specifically frontal and temporal epilepsy. Contrary to the common belief that childhood epilepsy would result in diffuse impairments, we were able to demonstrate that children manifest the same localized deficits as adult patients. In studies presently underway in

  4. Magnetic dipole discharges. III. Instabilities

    SciTech Connect

    Stenzel, R. L.; Urrutia, J. M.; Ionita, C.; Schrittwieser, R.

    2013-08-15

    Instabilities in a cross-field discharge around a permanent magnet have been investigated. The permanent magnet serves as a cold cathode and the chamber wall as an anode. The magnet is biased strongly negative and emits secondary electrons due to impact of energetic ions. The electrons outside the sheath are confined by the strong dipolar magnetic field and by the ion-rich sheath surrounding the magnet. The electron energy peaks in the equatorial plane where most ionization occurs and the ions are trapped in a negative potential well. The discharge mechanism is the same as that of cylindrical and planar magnetrons, but here extended to a 3-D cathode geometry using a single dipole magnet. While the basic properties of the discharge are presented in a companion paper, the present focus is on various observed instabilities. The first is an ion sheath instability which oscillates the plasma potential outside the sheath below the ion plasma frequency. It arises in ion-rich sheaths with low electron supply, which is the case for low secondary emission yields. Sheath oscillations modulate the discharge current creating oscillating magnetic fields. The second instability is current-driven ion sound turbulence due to counter-streaming electrons and ions. The fluctuations have a broad spectrum and short correlation lengths in all directions. The third type of fluctuations is spiky potential and current oscillations in high density discharges. These appear to be due to unstable emission properties of the magnetron cathode.

  5. Selected instability indices in Europe

    NASA Astrophysics Data System (ADS)

    Siedlecki, Mariusz

    2009-04-01

    A climatology of various parameters associated with severe weather and convective storms has been created for Europe that involves using radiosounding data collected at the University of Wyoming for the period from 1991 to 2005. The analysis is based on monthly means, frequency distributions of such parameters as convective available potential energy (CAPE), convective inhibition energy (CIN), KI - index, total totals index (TTI), and the severe weather threat index (SWEAT). Monthly average CAPE values exceeding 300 Jkg-1 are observed over the west Mediterranean Sea and the neighboring coastal countries. The similar seasonal cycle and spatial distributions exhibit CIN fields with summer monthly means above 100 Jkg-1 observed on the south part of the researched domain. The KI, TTI, and SWEAT indices, which assess both the lapse ratio between 850 and 500 hPa and low level humidity, show the privileged region (the Alpine area and the Carpathian Basin) with the highest instability conditions. Orography clearly plays an important role in this structure. Farther from this area, the monthly average decreases to the east, west, north, and south of the research domain. Ward’s procedure was applied to create objective regionalization according to instability conditions. This method tends to produce two regions with relatively different instability conditions and few subregions with similar conditions. The first region, covering the Alpine area, the west Mediterranean Sea, west Turkey and the southern Ukraine, is characterized by the highest instability. The rest of the investigated area is the second region with a more stable atmosphere.

  6. The Chemistry of Beer Instability

    ERIC Educational Resources Information Center

    Stewart, Graham G.

    2004-01-01

    Brewing of beer, one of the oldest biotechnology industries was one of the earliest processes to be undertaken on commercial basis. Biological instability involves contamination of bacteria, yeast, or mycelia fungi and there is always a risk in brewing that beer can become contaminated by micro-organisms.

  7. Edge instabilities of topological superconductors

    NASA Astrophysics Data System (ADS)

    Hofmann, Johannes S.; Assaad, Fakher F.; Schnyder, Andreas P.

    2016-05-01

    Nodal topological superconductors display zero-energy Majorana flat bands at generic edges. The flatness of these edge bands, which is protected by time-reversal and translation symmetry, gives rise to an extensive ground-state degeneracy. Therefore, even arbitrarily weak interactions lead to an instability of the flat-band edge states towards time-reversal and translation-symmetry-broken phases, which lift the ground-state degeneracy. We examine the instabilities of the flat-band edge states of dx y-wave superconductors by performing a mean-field analysis in the Majorana basis of the edge states. The leading instabilities are Majorana mass terms, which correspond to coherent superpositions of particle-particle and particle-hole channels in the fermionic language. We find that attractive interactions induce three different mass terms. One is a coherent superposition of imaginary s -wave pairing and current order, and another combines a charge-density-wave and finite-momentum singlet pairing. Repulsive interactions, on the other hand, lead to ferromagnetism together with spin-triplet pairing at the edge. Our quantum Monte Carlo simulations confirm these findings and demonstrate that these instabilities occur even in the presence of strong quantum fluctuations. We discuss the implications of our results for experiments on cuprate high-temperature superconductors.

  8. Lending sociodynamics and economic instability

    NASA Astrophysics Data System (ADS)

    Hawkins, Raymond J.

    2011-11-01

    We show how the dynamics of economic instability and financial crises articulated by Keynes in the General Theory and developed by Minsky as the Financial Instability Hypothesis can be formalized using Weidlich’s sociodynamics of opinion formation. The model addresses both the lending sentiment of a lender in isolation as well as the impact on that lending sentiment of the behavior of other lenders. The risk associated with lending is incorporated through a stochastic treatment of loan dynamics that treats prepayment and default as competing risks. With this model we are able to generate endogenously the rapid changes in lending opinion that attend slow changes in lending profitability and find these dynamics to be consistent with the rise and collapse of the non-Agency mortgage-backed securities market in 2007/2008. As the parameters of this model correspond to well-known phenomena in cognitive and social psychology, we can both explain why economic instability has proved robust to advances in risk measurement and suggest how policy for reducing economic instability might be formulated in an experimentally sound manner.

  9. Patient Safety: Guide to Safe Plastic Surgery

    MedlinePlus

    ... and Consumer Information > Patient Safety Guide to Safe Plastic Surgery Patient Safety More Resources Choose a surgeon ... Important facts about the safety and risks of plastic surgery Questions to ask my plastic surgeon Choose ...

  10. Large-Larmor-radius interchange instability

    SciTech Connect

    Ripin, B.H.; McLean, E.A.; Manka, C.K.; Pawley, C.; Stamper, J.A.; Peyser, T.A.; Mostovych, A.N.; Grun, J.; Hassam, A.B.; Huba, J.

    1987-11-16

    We observe linear and nonlinear features of a strong plasma/magnetic field interchange Rayleigh-Taylor instability in the limit of large ion Larmor radius. The instability undergoes rapid linear growth culminating in free-streaming flute tips.

  11. In-silico investigation of Rayleigh instability in ultra-thin copper nanowire in premelting regime

    SciTech Connect

    Dutta, Amlan; Chatterjee, Swastika; Raychaudhuri, A. K.; Moitra, Amitava; Saha-Dasgupta, T.

    2014-06-28

    Motivated by the recent experimental reports, we explore the formation of Rayleigh-like instability in metallic nanowires during the solid state annealing, a concept originally introduced for liquid columns. Our molecular dynamics study using realistic interatomic potential reveals instability induced pattern formation at temperatures even below the melting temperature of the wire, in accordance with the experimental observations. We find that this is driven by the surface diffusion, which causes plastic slips in the system initiating necking in the nanowire. We further find the surface dominated mass-transport is of subdiffusive nature with time exponent less than unity. Our study provides an atomistic perspective of the instability formation in nanostructured solid phase.

  12. c-MYC-Induced Genomic Instability

    PubMed Central

    Kuzyk, Alexandra; Mai, Sabine

    2014-01-01

    MYC dysregulation initiates a dynamic process of genomic instability that is linked to tumor initiation. Early studies using MYC-carrying retroviruses showed that these viruses were potent transforming agents. Cell culture models followed that addressed the role of MYC in transformation. With the advent of MYC transgenic mice, it became obvious that MYC deregulation alone was sufficient to initiate B-cell neoplasia in mice. More than 70% of all tumors have some form of c-MYC gene dysregulation, which affects gene regulation, microRNA expression profiles, large genomic amplifications, and the overall organization of the nucleus. These changes set the stage for the dynamic genomic rearrangements that are associated with cellular transformation. PMID:24692190

  13. Singlet and triplet instability theorems

    SciTech Connect

    Yamada, Tomonori; Hirata, So

    2015-09-21

    A useful definition of orbital degeneracy—form-degeneracy—is introduced, which is distinct from the usual energy-degeneracy: Two canonical spatial orbitals are form-degenerate when the energy expectation value in the restricted Hartree–Fock (RHF) wave function is unaltered upon a two-electron excitation from one of these orbitals to the other. Form-degenerate orbitals tend to have isomorphic electron densities and occur in the highest-occupied and lowest-unoccupied molecular orbitals (HOMOs and LUMOs) of strongly correlated systems. Here, we present a mathematical proof of the existence of a triplet instability in a real or complex RHF wave function of a finite system in the space of real or complex unrestricted Hartree–Fock wave functions when HOMO and LUMO are energy- or form-degenerate. We also show that a singlet instability always exists in a real RHF wave function of a finite system in the space of complex RHF wave functions, when HOMO and LUMO are form-degenerate, but have nonidentical electron densities, or are energy-degenerate. These theorems provide Hartree–Fock-theory-based explanations of Hund’s rule, a singlet instability in Jahn–Teller systems, biradicaloid electronic structures, and a triplet instability during some covalent bond breaking. They also suggest (but not guarantee) the spontaneous formation of a spin density wave (SDW) in a metallic solid. The stability theory underlying these theorems extended to a continuous orbital-energy spectrum proves the existence of an oscillating (nonspiral) SDW instability in one- and three-dimensional homogeneous electron gases, but only at low densities or for strong interactions.

  14. Singlet and triplet instability theorems

    NASA Astrophysics Data System (ADS)

    Yamada, Tomonori; Hirata, So

    2015-09-01

    A useful definition of orbital degeneracy—form-degeneracy—is introduced, which is distinct from the usual energy-degeneracy: Two canonical spatial orbitals are form-degenerate when the energy expectation value in the restricted Hartree-Fock (RHF) wave function is unaltered upon a two-electron excitation from one of these orbitals to the other. Form-degenerate orbitals tend to have isomorphic electron densities and occur in the highest-occupied and lowest-unoccupied molecular orbitals (HOMOs and LUMOs) of strongly correlated systems. Here, we present a mathematical proof of the existence of a triplet instability in a real or complex RHF wave function of a finite system in the space of real or complex unrestricted Hartree-Fock wave functions when HOMO and LUMO are energy- or form-degenerate. We also show that a singlet instability always exists in a real RHF wave function of a finite system in the space of complex RHF wave functions, when HOMO and LUMO are form-degenerate, but have nonidentical electron densities, or are energy-degenerate. These theorems provide Hartree-Fock-theory-based explanations of Hund's rule, a singlet instability in Jahn-Teller systems, biradicaloid electronic structures, and a triplet instability during some covalent bond breaking. They also suggest (but not guarantee) the spontaneous formation of a spin density wave (SDW) in a metallic solid. The stability theory underlying these theorems extended to a continuous orbital-energy spectrum proves the existence of an oscillating (nonspiral) SDW instability in one- and three-dimensional homogeneous electron gases, but only at low densities or for strong interactions.

  15. Singlet and triplet instability theorems.

    PubMed

    Yamada, Tomonori; Hirata, So

    2015-09-21

    A useful definition of orbital degeneracy—form-degeneracy—is introduced, which is distinct from the usual energy-degeneracy: Two canonical spatial orbitals are form-degenerate when the energy expectation value in the restricted Hartree-Fock (RHF) wave function is unaltered upon a two-electron excitation from one of these orbitals to the other. Form-degenerate orbitals tend to have isomorphic electron densities and occur in the highest-occupied and lowest-unoccupied molecular orbitals (HOMOs and LUMOs) of strongly correlated systems. Here, we present a mathematical proof of the existence of a triplet instability in a real or complex RHF wave function of a finite system in the space of real or complex unrestricted Hartree-Fock wave functions when HOMO and LUMO are energy- or form-degenerate. We also show that a singlet instability always exists in a real RHF wave function of a finite system in the space of complex RHF wave functions, when HOMO and LUMO are form-degenerate, but have nonidentical electron densities, or are energy-degenerate. These theorems provide Hartree-Fock-theory-based explanations of Hund's rule, a singlet instability in Jahn-Teller systems, biradicaloid electronic structures, and a triplet instability during some covalent bond breaking. They also suggest (but not guarantee) the spontaneous formation of a spin density wave (SDW) in a metallic solid. The stability theory underlying these theorems extended to a continuous orbital-energy spectrum proves the existence of an oscillating (nonspiral) SDW instability in one- and three-dimensional homogeneous electron gases, but only at low densities or for strong interactions. PMID:26395692

  16. Hydrodynamic instability measurements in DT-layered ICF capsules using the layered-HGR platform

    NASA Astrophysics Data System (ADS)

    Weber, C.; Döppner, T.; Casey, D.; Bunn, T.; Carlson, L.; Dylla-Spears, R.; Kozioziemski, B.; MacPhee, A. G.; Sater, J.; Nikroo, A.; Robey, H.; Smalyuk, V.

    2016-05-01

    The first measurements of hydrodynamic instability growth at the fuel-ablator interface in an ICF implosion are reported. Previous instability measurements on the National Ignition Facility have used plastic capsules to measure ablation front Rayleigh-Taylor growth with the Hydro.-Growth Radiography (HGR) platform. These capsules substituted an additional thickness of plastic ablator material in place of the cryogenic layer of Deuterium- Tritium (DT) fuel. The present experiments are the first to include a DT ice layer, which enables measurements of the instability growth occurring at the fuel-ablator interface. Instability growth at the fuel-ablator interface is seeded differently in two independent NIF experiments. In the first case, a perturbation on the outside of the capsule feeds through and grows on the interface. Comparisons to an implosion without a fuel layer produce a measure of the fuel's modulation. In the second case, a modulation was directly machined on the inner ablator before the fuel layer was added. The measurement of growth in these two scenarios are compared to 2D rad-hydro modeling.

  17. Modeling anisotropic plasticity: Eulerian hydrocode applications of high strain-rate deformation processes

    SciTech Connect

    Clancy, S.P.; Burkett, M.W.; Maudlin, P.J.

    1998-02-01

    Previously developed constitutive models and solution algorithms for anisotropic elastoplastic material strength are implemented in the two dimensional MESA hydrodynamics code. Quadratic yield functions fitted from polycrystal simulations for a metallic hexagonal-close-packed structure are utilized. An associative flow strength formulation incorporating these yield functions is solved using a geometric normal return method. A stretching rod problem is selected to investigate the effects of material anisotropy on a tensile plastic instability (necking). The rod necking rate and topology are compared for MESA simulations performed for both isotropic and anisotropic cases utilizing the elastic-perfectly-plastic and the Mechanical Threshold Stress flow stress models.

  18. Midcarpal Instability: A Comprehensive Review and Update.

    PubMed

    Niacaris, Timothy; Ming, Bryan W; Lichtman, David M

    2015-08-01

    Midcarpal instability has been well described as a clinical entity but the pathokinematics and pathologic anatomy continue to be poorly understood. This article presents a comprehensive review of the existing knowledge and literature-based evidence for the diagnosis and management of the various entities comprising midcarpal instability. It discusses the limitations of the current understanding of midcarpal instability and proposes new directions for furthering knowledge of the causes and treatment of midcarpal instability and wrist pathomechanics in general. PMID:26205710

  19. Measurements of fast transition instability in RHIC

    SciTech Connect

    Ptitsyn, V.; Blaskiewicz, M.; Fischer, W.; Lee, R.; Zhang, S.Y.

    2010-05-23

    A fast transition instability presents a limiting factor for ion beam intensity in RHIC. Several pieces of evidence show that electron clouds play an important role in establishing the threshold of this instability. In RHIC Runs8 the measurements of the instability, using a button BPM, were done in order to observe details of the instability development on the scale over hundreds and thousands turns. The paper presents and discusses the results of those measurements in time and frequency domains.

  20. Dynamic ultrasound of peroneal tendon instability.

    PubMed

    Pesquer, Lionel; Guillo, Stéphane; Poussange, Nicolas; Pele, Eric; Meyer, Philippe; Dallaudière, Benjamin

    2016-07-01

    Ankle snapping may be caused by peroneal tendon instability. Anterior instability occurs after traumatic superior peroneal retinaculum injury, whereas peroneal tendon intrasheath subluxation is atraumatic. Whereas subluxation is mainly dynamic, ultrasound allows for the diagnosis and classification of peroneal instability because it allows for real-time exploration. The purpose of this review is to describe the anatomic and physiologic bases for peroneal instability and to heighten the role of dynamic ultrasound in the diagnosis of snapping. PMID:26943704

  1. Vacuum revealed: The final state of vacuum instabilities in compact stars

    SciTech Connect

    Pani, Paolo; Cardoso, Vitor; Berti, Emanuele; Read, Jocelyn; Salgado, Marcelo

    2011-04-15

    Quantum fields in compact stars can be amplified due to a semiclassical instability, which may affect the structure of relativistic stars. We show that a classical counterpart to this instability occurs in exactly the same region of the parameter space. For negative coupling parameter {xi}, the instability is related to the well-known ''spontaneous scalarization'' effect. The plausible end state is a static, asymptotically flat configuration with a nonzero scalar field, which is compatible with weak-field experiments and energetically favored over stellar solutions in general relativity. For {xi}>0 the new configurations are energetically disfavored, and the end state of the instability remains an open issue. The vacuum instability may lead to new experimental opportunities to probe the nature of vacuum energy via astrophysical observations of compact stars.

  2. Particular Threshold Behavior of Dusty Plasma Instabilities

    SciTech Connect

    Mikikian, M.; Cavarroc, M.; Coueedel, L.; Tessier, Y.; Boufendi, L.

    2008-09-07

    We show that some experimentally observed instabilities, concerning the void region of a dust cloud, are similar to oscillations obtained in chemical systems or neuronal dynamics. The time evolution of these instabilities follows a well-defined process particularly visible in the instability shape and frequency.

  3. Basic instabilities of collisionless gravitating systems.

    NASA Astrophysics Data System (ADS)

    Polyachenko, V. L.

    1995-05-01

    The paper presents a short summary of basic instabilities in stellar systems, namely: the Jeans, bar-mode and fire-hose (bending) instabilities. A classification of bar-mode instabilities according to a ratio of the bar pattern angular velocity and the maximal precession speed of nearly-circular stellar orbits is proposed.

  4. Transverse instability at the recycler ring

    SciTech Connect

    Ng, K.Y.; /Fermilab

    2004-10-01

    Sporadic transverse instabilities have been observed at the Fermilab Recycler Ring leading to increase in transverse emittances and beam loss. The driving source of these instabilities has been attributed to the resistive-wall impedance with space-charge playing an important role in suppressing Landau damping. Growth rates of the instabilities are computed. Remaining problems are discussed.

  5. Solitons versus parametric instabilities during ionospheric heating

    NASA Technical Reports Server (NTRS)

    Nicholson, D. R.; Payne, G. L.; Downie, R. M.; Sheerin, J. P.

    1984-01-01

    Various effects associated with ionospheric heating are investigated by numerically solving the modified Zakharov (1972) equations. It is shown that, for typical ionospheric parameters, the modulational instability is more important than the parametric decay instability in the spatial region of strongest heater electric field. It is concluded that the modulational instability leads to the formation of solitons, as originally predicted by Petviashvili (1976).

  6. Control of laser plasma instabilities in hohlraums

    SciTech Connect

    Kruer, W.L.

    1996-12-01

    Laser plasma instabilities are an important constraint on the operating regime for inertial fusion. Many techniques have been developed to control the various laser-driven instabilities. Experiments with long scale length plasmas are testing these instability levels, the nonlinear regimes, and the control mechanisms.

  7. Extruding plastic scintillator at Fermilab

    SciTech Connect

    Anna Pla-Dalmau; Alan D. Bross; Victor V. Rykalin

    2003-10-31

    An understanding of the costs involved in the production of plastic scintillators and the development of a less expensive material have become necessary with the prospects of building very large plastic scintillation detectors. Several factors contribute to the high cost of plastic scintillating sheets, but the principal reason is the labor-intensive nature of the manufacturing process. In order to significantly lower the costs, the current casting procedures had to be abandoned. Since polystyrene is widely used in the consumer industry, the logical path was to investigate the extrusion of commercial-grade polystyrene pellets with dopants to yield high quality plastic scintillator. This concept was tested and high quality extruded plastic scintillator was produced. The D0 and MINOS experiments are already using extruded scintillator strips in their detectors. An extrusion line has recently been installed at Fermilab in collaboration with NICADD (Northern Illinois Center for Accelerator and Detector Development). This new facility will serve to further develop and improve extruded plastic scintillator. This paper will discuss the characteristics of extruded plastic scintillator and its raw materials, the different manufacturing techniques and the current R&D program at Fermilab.

  8. Research and Development of a New Waste Collection Bin to Facilitate Education in Plastic Recycling

    ERIC Educational Resources Information Center

    Chow, Cheuk-fai; So, Wing-Mui Winnie; Cheung, Tsz-Yan

    2016-01-01

    Plastic recycling has been an alternative method for solid waste management apart from landfill and incineration. However, recycling quality is affected when all plastics are discarded into a single recycling bin that increases cross contaminations and operation cost to the recycling industry. Following the engineering design process, a new…

  9. CORN GLUTEN MEAL AS A THERMOPLASTIC RESIN: EFFECT OF PLASTICIZERS AND WATER CONTENT

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Corn gluten meal (CGM) was studied to investigate the effect plasticizers and water have on its melt processing, and how this melting affects its mechanical properties. CGM containing varying amounts of water were mixed with 30%(w/w) plasticizers; (glycerol, triethylene glycol (TEG), dibutyl tartra...

  10. Validity and reliability of the SPORTS score for shoulder instability

    PubMed Central

    BLONNA, DAVIDE; BELLATO, ENRICO; CARANZANO, FRANCESCO; BONASIA, DAVIDE E.; MARMOTTI, ANTONGIULIO; ROSSI, ROBERTO; CASTOLDI, FILIPPO

    2014-01-01

    Purpose athletes affected by shoulder instability cannot be judged solely according to the criteria used for non-athletes. In order to improve the assessment of shoulder instability surgery outcomes, the SPORTS score was tested in a cohort of athletes. Methods ninety-eight athletes at an average follow-up of 4.6 years (range 1–9.2) after open or arthroscopic surgery for recurrent anterior shoulder instability were included in this study. The patients were asked to complete the SPORTS score questionnaire twice, with an interval of 2–3 weeks between the two assessments. The Bland-Altman method and the intra-class correlation coefficient were used to measure reliability. Criterion validity was assessed by calculating the Spearman correlation coefficient between the SPORTS score and the Western Ontario Shoulder Instability Index (WOSI) score, the Rowe score, the Oxford Shoulder Instability Score (OSIS), and the Subjective Shoulder Value (SSV). Results the SPORTS score showed excellent test-retest reliability. The systematic error between the first and the second assessment was 0.3 points (95% upper limit of agreement = 2.3 points). The criterion validity was found to be strong for the SPORTS score, which correlated best with the SSV and the “sport, recreation, and work” component of the WOSI score. The SPORTS score had an acceptable floor effect (8%). The ceiling effect was 46%, which was better than the ceiling effects seen with the Rowe, OSIS and WOSI scores. Conclusions this study suggests that the SPORTS score is a valid score in the assessment of athletes after surgery for shoulder instability and that it adds important information to the currently available scores. Level of evidence Level III, diagnostic study of nonconsecutive patients. PMID:25606544

  11. Absolute/convective instability of planar viscoelastic jets

    NASA Astrophysics Data System (ADS)

    Ray, Prasun K.; Zaki, Tamer A.

    2015-01-01

    Spatiotemporal linear stability analysis is used to investigate the onset of local absolute instability in planar viscoelastic jets. The influence of viscoelasticity in dilute polymer solutions is modeled with the FENE-P constitutive equation which requires the specification of a non-dimensional polymer relaxation time (the Weissenberg number, We), the maximum polymer extensibility, L, and the ratio of solvent and solution viscosities, β. A two-parameter family of velocity profiles is used as the base state with the parameter, S, controlling the amount of co- or counter-flow while N-1 sets the thickness of the jet shear layer. We examine how the variation of these fluid and flow parameters affects the minimum value of S at which the flow becomes locally absolutely unstable. Initially setting the Reynolds number to Re = 500, we find that the first varicose jet-column mode dictates the presence of absolute instability, and increasing the Weissenberg number produces important changes in the nature of the instability. The region of absolute instability shifts towards thin shear layers, and the amount of back-flow needed for absolute instability decreases (i.e., the influence of viscoelasticity is destabilizing). Additionally, when We is sufficiently large and N-1 is sufficiently small, single-stream jets become absolutely unstable. Numerical experiments with approximate equations show that both the polymer and solvent contributions to the stress become destabilizing when the scaled shear rate, η = /W e dU¯1/dx 2L ( /d U ¯ 1 d x 2 is the base-state velocity gradient), is sufficiently large. These qualitative trends are largely unchanged when the Reynolds number is reduced; however, the relative importance of the destabilizing stresses increases tangibly. Consequently, absolute instability is substantially enhanced, and single-stream jets become absolutely unstable over a sizable portion of the parameter space.

  12. Generalized laser filamentation instability coupled to cooling instability

    SciTech Connect

    Liang, E.P.; Wong, J.; Garrison, J.

    1984-04-24

    We consider the propagation of laser light in an initially slightly nonuniform plasma. The classical dispersion relation for the laser filamentation growth rate (see e.g., B. Langdon, in the 1980 Lawrence Livermore National Laboratory Laser Program Annual Report, pp. 3-56, UCRL-50021-80, 1981) can be generalized to include other acoustical effects. For example, we find that the inclusion of potential imbalances in the heating and cooling rates of the ambient medium due to density and temperature perturbations can cause the laser filamentation mode to bifurcate into a cooling instability mode at long acoustic wavelengths. We also attempt to study semi-analytically the nonlinear evolution of this and related instabilities. These results have wide applications to a variety of chemical gas lasers and phenomena related to laser-target interactions (e.g., jet-like behavior).

  13. Excitation of parametric instabilities by radio waves in the ionosphere.

    NASA Technical Reports Server (NTRS)

    Fejer, J. A.; Leer, E.

    1972-01-01

    The excitation of parametric instabilities by radio waves in a magnetoplasma is discussed. A uniform medium is assumed and linear approximations are used. Excitation by a pump wave of ordinary polarization is hardly affected by the magnetic field. Low or zero frequency ion waves and high frequency Langmuir waves are excited simultaneously. For an extraordinary pump wave, the excited high frequency electrostatic waves are in the Bernstein mode. The threshold is slightly higher and excitation can occur only within certain 'allowed' frequency bands. A new type of parametric instability in which the excited waves are electromagnetic in nature and which is more strongly affected by the inhomogeneous nature of the medium is discussed qualitatively.

  14. Respiratory supercomplexes: plasticity and implications

    PubMed Central

    Porras, Christina A.; Bai, Yidong

    2015-01-01

    The plasticity model of the electron transport chain has slowly begun to replace both the liquid model of free complexes and the solid model of supercomplexes. The plasticity model predicts that respiratory complexes exist and function both as single complexes and as supercomplexes. The advantages of this system is an electron transport train which is able to adapt to changes in its environment. This review will investigate the current body of work on supercomplexes including their assembly, regulation, and plasticity, and particularly their role in the generation of reactive oxygen species and aging. PMID:25553469

  15. Circadian Regulation of Synaptic Plasticity.

    PubMed

    Frank, Marcos G

    2016-01-01

    Circadian rhythms refer to oscillations in biological processes with a period of approximately 24 h. In addition to the sleep/wake cycle, there are circadian rhythms in metabolism, body temperature, hormone output, organ function and gene expression. There is also evidence of circadian rhythms in synaptic plasticity, in some cases driven by a master central clock and in other cases by peripheral clocks. In this article, I review the evidence for circadian influences on synaptic plasticity. I also discuss ways to disentangle the effects of brain state and rhythms on synaptic plasticity. PMID:27420105

  16. The commercialization of plastic surgery.

    PubMed

    Swanson, Eric

    2013-09-01

    The last decade has brought a major challenge to the traditional practice of plastic surgery from corporations that treat plastic surgery as a commercial product and market directly to the public. This corporate medicine model may include promotion of a trademarked procedure or device, national advertising that promises stunning results, sales consultants, and claims of innovation, superiority, and improved safety. This article explores the ethics of this business practice and whether corporate medicine is a desirable model for patients and plastic surgeons. PMID:24081699

  17. Plastic surgery on identical twins.

    PubMed

    Mühlbauer, W

    1991-01-01

    Four pairs of identical female twins have undergone a variety of plastic surgery procedures, including rhinoplasties, rhytidectomies, augmentation mammaplasties, and trochanteric liposuction. Performing plastic surgery on identical twins implies special considerations: the extent of preoperative phenotypic identity, the behavior of each twin (dominant or recessive), the twins' personal interdependence and individual expectations, the operative strategy (simultaneous versus sequential operations), the eventual complications, and the extent to which the operative results and postoperative appearance are identical. In general, counseling, operative technique, and responsibility for producing good results place greater demands on surgeons when performing plastic surgery on identical twins than on singletons. Still, the results have been gratifying. PMID:1994809

  18. Interface instability modes in freezing colloidal suspensions: revealed from onset of planar instability

    PubMed Central

    Wang, Lilin; You, Jiaxue; Wang, Zhijun; Wang, Jincheng; Lin, Xin

    2016-01-01

    Freezing colloidal suspensions widely exists in nature and industry. Interface instability has attracted much attention for the understandings of the pattern formation in freezing colloidal suspensions. However, the interface instability modes, the origin of the ice banding or ice lamellae, are still unclear. In-situ experimental observation of the onset of interface instability remains absent up to now. Here, by directly imaging the initial transient stage of planar interface instability in directional freezing colloidal suspensions, we proposed three interface instability modes, Mullins-Sekerka instability, global split instability and local split instability. The intrinsic mechanism of the instability modes comes from the competition of the solute boundary layer and the particle boundary layer, which only can be revealed from the initial transient stage of planar instability in directional freezing. PMID:26996630

  19. Interface instability modes in freezing colloidal suspensions: revealed from onset of planar instability

    NASA Astrophysics Data System (ADS)

    Wang, Lilin; You, Jiaxue; Wang, Zhijun; Wang, Jincheng; Lin, Xin

    2016-03-01

    Freezing colloidal suspensions widely exists in nature and industry. Interface instability has attracted much attention for the understandings of the pattern formation in freezing colloidal suspensions. However, the interface instability modes, the origin of the ice banding or ice lamellae, are still unclear. In-situ experimental observation of the onset of interface instability remains absent up to now. Here, by directly imaging the initial transient stage of planar interface instability in directional freezing colloidal suspensions, we proposed three interface instability modes, Mullins-Sekerka instability, global split instability and local split instability. The intrinsic mechanism of the instability modes comes from the competition of the solute boundary layer and the particle boundary layer, which only can be revealed from the initial transient stage of planar instability in directional freezing.

  20. Ecology and plastics

    SciTech Connect

    Nelson, G.L.

    1995-12-01

    Materials are used in applications for well-defined reasons. For example, plastics used in electrical and electric applications for enclosures must resistant impact and heat as well as ignition. The emergence of ``green`` products with the requirement for recyclability has added a new dimension to product design. The issue is more than material recyclability, however simple or complex that may be; it involves rethinking the entire end-product life cycle to develop products that have a lesser effect on human health and the environment than do alternative products. In the information and telecommunications products industries, companies have been involved in life-cycle analysis and in the development of environmentally conscious products (ECPs) for some time. In November 1991 IBM established an Engineering Center for Environmentally Conscious Products at IBM, Research Triangle Park, NC. The mission of the Engineering Center is to provide guidance and leadership in the development and manufacturing of ECPs which are safe for their intended use, protective of the environment and that can be recycled, re-utilized, or disposed of safely. The paper discusses new laws being enacted that require recycling, marking, ecolabeling, and new product take back.

  1. Elastic-plastic failure analysis of pressure burst tests of thin toroidal shells

    SciTech Connect

    Jones, D.P.; Holliday, J.E.; Larson, L.D.

    1998-07-01

    This paper provides a comparison between test and analysis results for bursting of thin toroidal shells. Testing was done by pressurizing two toroidal shells until failure by bursting. An analytical criterion for bursting is developed based on good agreement between structural instability predicted by large strain-large displacement elastic-plastic finite element analysis and observed burst pressure obtained from test. The failures were characterized by loss of local stability of the membrane section of the shells consistent with the predictions from the finite element analysis. Good agreement between measured and predicted burst pressure suggests that incipient structural instability as calculated by an elastic-plastic finite element analysis is a reasonable way to calculate the bursting pressure of thin membrane structures.

  2. Cross-shelf transport and dispersion due to baroclinic instabilities

    NASA Astrophysics Data System (ADS)

    Thyng, Kristen; Hetland, Robert

    2014-05-01

    The dominant forcing mechanisms for the circulation in the northwestern Gulf of Mexico are largely determined by location relative to the shelf break. On the inner shelf, the flow is mostly controlled by the wind and on the outer shelf is affected by the mesoscale loop-current eddies. However, in the summer, baroclinic instabilities can develop along the boundary of the mid-shelf river plume front, leading to large eddies (~50 km length scale) that can reach across the entire shelf and strongly affect the local flow field. These instabilities advect fresher water toward the shelf edge and pull denser water back toward the coast. The details of how the flow crosses between these two regimes is of interest because it controls the flux of river-borne biogeochemical properties to the deep ocean, as well as for the potential onshore transport of oil from offshore spills. We approach this problem using a high resolution numerical model of the Texas-Louisiana shelf run using the Regional Ocean Modeling System (ROMS) and a Lagrangian particle tracking model (TRACMASS). By initializing drifters at the sources of fresh water (the Atchafalaya and Mississippi rivers) in the numerical model, we are able to explicitly track its trajectory through the numerical domain in time. These trajectories can then be used to characterize the cross-shelf transport and lateral dispersion due to the instabilities caused by the presence of the fresher water. We expect the transport and dispersion to be enhanced when compared with these quantities at other times of the year when the instabilities are not present, as well as with other regions of the shelf break that are farther from the plume edge area. Additionally, an idealized numerical model of a shelf break with both horizontal and vertical density gradients has been run through relevant parameter spaces to examine the range of baroclinic instabilities. Drifters are run in these simulations for comparison of transport and dispersion with

  3. The Zombie Instability: Using Numerical Simulation to Design a Laboratory Experiment

    NASA Astrophysics Data System (ADS)

    Wang, Meng; Pei, Suyang; Jiang, Chung-Hsiang; Hassanzadeh, Pedram; Marcus, Philip

    2014-11-01

    A new type of finite amplitude-instability has been found in numerical simulations of stratified, rotating, shear flows. The instability occurs via baroclinic critical layers that create linearly unstable vortex layers, which roll-up into vortices. Under the right conditions, those vortices can form a new generation of vortices, resulting in ``vortex self-replication'' that fills the fluid with vortices. Creating this instability in a laboratory would provide further evidence for the existence of the instability, which we first found in numerical simulations of protoplanetary disks. To design a laboratory experiment we need to know how the flow parameters-- shear, rotation and stratification, etc. affect the instability. To build an experiment economically, we also need to know how the finite-amplitude trigger of the instability scales with viscosity and the size of the domain. In this talk, we summarize our findings. We present a map, in terms of the experimentally controllable parameters, that shows where the instability occurs and whether the instability creates a few isolated transient vortices, a few long-lived vortices, or long-lived, self-replicating vortices that fill the entire flow.

  4. A Numerical Study of Feathering Instability

    NASA Astrophysics Data System (ADS)

    Lee, Wing-Kit; Wang, Hsiang-Hsu

    2016-06-01

    The stability of a spiral shock of self-gravitating, magnetized interstellar medium is studied by performing two-dimensional numerical simulations of a local patch of tight-winding spiral arm. As previously suggested by the linear studies, two types of instabilities are identified, namely, wiggle instability and feathering instability. The former instability occurs in the hydrodynamics limit and results in short wavelength perturbations. On the other hand, the feathering instability requires both self-gravitating and magnetic fields and results in wider structures.

  5. New Instabilities in Line Driven Winds

    NASA Technical Reports Server (NTRS)

    Martens, P. C. H.

    1985-01-01

    The physical mechanisms which potentially lead to instabilities in line driven winds, the drift instability and the line shape instability, are discussed. A general three dimensional treatment of the stability problem of line driven winds which leads to the general dispersion equation is proposed. From this dispersion equation automatically a third physical mechanism driving instability in stellar winds is deduced; the thermal drift instability which is related to changes in absorption of radiation caused by temperature perturbations. This mechanism results in growing inwardly propagating sound waves.

  6. Granular Rayleigh-Taylor instability

    SciTech Connect

    Vinningland, Jan Ludvig; Johnsen, Oistein; Flekkoey, Eirik G.; Maaloey, Knut Joergen; Toussaint, Renaud

    2009-06-18

    A granular instability driven by gravity is studied experimentally and numerically. The instability arises as grains fall in a closed Hele-Shaw cell where a layer of dense granular material is positioned above a layer of air. The initially flat front defined by the grains subsequently develops into a pattern of falling granular fingers separated by rising bubbles of air. A transient coarsening of the front is observed right from the start by a finger merging process. The coarsening is later stabilized by new fingers growing from the center of the rising bubbles. The structures are quantified by means of Fourier analysis and quantitative agreement between experiment and computation is shown. This analysis also reveals scale invariance of the flow structures under overall change of spatial scale.

  7. MHD Instabilities at the Heliopause

    SciTech Connect

    Dasgupta, B.; Florinski, V.; Heerikhuisen, J.; Zank, G. P.

    2006-09-26

    The heliopause (HP) is the outer edge of the heliosphere which separates the tenuous and hot heliosheath plasma on one side and the relatively dense and cool magnetized interstellar plasma on the other side. As a surface of tangential discontinuity, the HP is subjected to both Rayleigh-Taylor (RT) and Kelvin-Helmholtz (KH) instabilities. The coupling between plasma ions and neutral atoms through the process of charge exchange provides an ''effective gravity'' at the HP, while a shear flow exists across it. We derive analytically the linearized dispersion relation for waves propagating along the surface of this discontinuity, which represents a combined RT/KH analysis. We investigate both the purely hydrodynamic, as well as magnetohydrodynamic, cases, and find that interstellar and heliospheric magnetic fields can help stabilize the HP for RT and KH-type instabilities.

  8. Nonlinear evolution of Buneman instability

    NASA Astrophysics Data System (ADS)

    Ishihara, O.; Hirose, A.; Langdon, A. B.

    1981-03-01

    The nonlinear evolution of one-dimensional electron-ion two-stream instability in a field-free plasma is investigated analytically and by computer simulation. The instability is dominated by the fastest growing mode and its harmonics, provided that the initial fluctuation level is sufficiently small. A nonlinear dispersion relation is obtained and solved numerically, with allowance for the frequency and growth rate modulation, the electric field up to a specified order, and the renormalized particle distribution functions. It is shown that the model can explain computer simulation results, including the presence of an algebraic growth stage following the breakdown of the exponential linear growth, the appearance of harmonics, and the final saturation level.

  9. Feedback control of resistive instabilities

    SciTech Connect

    White, R.B.; Rutherford, P.H.; Furth, H.P.; Park, W.; Chen, L.

    1985-12-01

    Resistive instabilities are responsible for much of the global behavior and the determination of the possible domains of operation of tokamaks. Their successful control could have definite advantages, even making available new regimes of operation. Elimination of sawtoothing might allow operation with higher currents and more peaked current profiles, with q on axis well below unity. In this work different feedback schemes are explored. Simple analytical derivations of the effects of local heating and current drive feedback are presented. Although control of modes with m greater than or equal to 2 is fairly straightforward, the control of the m = 1 mode is more difficult because of its proximity to ideal instability. The most promising scheme utilizes high energy trapped particles. 20 refs., 3 figs.

  10. Numerical analysis of engine instability

    NASA Astrophysics Data System (ADS)

    Habiballah, M.; Dubois, I.

    Following a literature review on numerical analyses of combustion instability, to give the state of the art in the area, the paper describes the ONERA methodology used to analyze the combustion instability in liquid propellant engines. Attention is also given to a model (named Phedre) which describes the unsteady turbulent two-phase reacting flow in a liquid rocket engine combustion chamber. The model formulation includes axial or radial propellant injection, baffles, and acoustic resonators modeling, and makes it possible to treat different engine types. A numerical analysis of a cryogenic engine stability is presented, and the results of the analysis are compared with results of tests of the Viking engine and the gas generator of the Vulcain engine, showing good qualitative agreement and some general trends between experiments and numerical analysis.

  11. A cosmic ray driven instability

    NASA Technical Reports Server (NTRS)

    Dorfi, E. A.; Drury, L. O.

    1985-01-01

    The interaction between energetic charged particles and thermal plasma which forms the basis of diffusive shock acceleration leads also to interesting dynamical phenomena. For a compressional mode propagating in a system with homogeneous energetic particle pressure it is well known that friction with the energetic particles leads to damping. The linear theory of this effect has been analyzed in detail by Ptuskin. Not so obvious is that a non-uniform energetic particle pressure can addition amplify compressional disturbances. If the pressure gradient is sufficiently steep this growth can dominate the frictional damping and lead to an instability. It is important to not that this effect results from the collective nature of the interaction between the energetic particles and the gas and is not connected with the Parker instability, nor with the resonant amplification of Alfven waves.

  12. The effect of spin induced magnetization on Jeans instability of viscous and resistive quantum plasma

    SciTech Connect

    Sharma, Prerana; Chhajlani, R. K.

    2014-03-15

    The effect of spin induced magnetization and electrical resistivity incorporating the viscosity of the medium is examined on the Jeans instability of quantum magnetoplasma. Formulation of the system is done by using the quantum magnetohydrodynamic model. The analysis of the problem is carried out by normal mode analysis theory. The general dispersion relation is derived from set of perturbed equations to analyse the growth rate and condition of self-gravitational Jeans instability. To discuss the influence of resistivity, magnetization, and viscosity parameters on Jeans instability, the general dispersion relation is reduced for both transverse and longitudinal mode of propagations. In the case of transverse propagation, the gravitating mode is found to be affected by the viscosity, magnetization, resistivity, and magnetic field strength whereas Jeans criterion of instability is modified by the magnetization and quantum parameter. In the longitudinal mode of propagation, the gravitating mode is found to be modified due to the viscosity and quantum correction in which the Jeans condition of instability is influenced only by quantum parameter. The other non-gravitating Alfven mode in this direction is affected by finite electrical resistivity, spin induced magnetization, and viscosity. The numerical study for the growth rate of Jeans instability is carried out for both in the transverse and longitudinal direction of propagation to the magnetic field. The effect of various parameters on the growth rate of Jeans instability in quantum plasma is analysed.

  13. THERMAL DEPOLYMERIZATION OF POSTCONSUMER PLASTICS

    EPA Science Inventory

    The University of North Dakota Energy & Environmental Research Center (EERC) performed two series of tests to evaluate process conditions for thermal depolymerization of postconsumer plastics. The objective of the first test series was to provide data for optimization of reactio...

  14. WEATHERABILITY OF ENHANCED DEGRADABLE PLASTICS

    EPA Science Inventory

    The main objective of this study was to assess the performance and the associated variability of several selected enhanced degradable plastic materials under a variety of different exposure conditions. ther objectives were to identify the major products formed during degradation ...

  15. Network Plasticity as Bayesian Inference

    PubMed Central

    Legenstein, Robert; Maass, Wolfgang

    2015-01-01

    General results from statistical learning theory suggest to understand not only brain computations, but also brain plasticity as probabilistic inference. But a model for that has been missing. We propose that inherently stochastic features of synaptic plasticity and spine motility enable cortical networks of neurons to carry out probabilistic inference by sampling from a posterior distribution of network configurations. This model provides a viable alternative to existing models that propose convergence of parameters to maximum likelihood values. It explains how priors on weight distributions and connection probabilities can be merged optimally with learned experience, how cortical networks can generalize learned information so well to novel experiences, and how they can compensate continuously for unforeseen disturbances of the network. The resulting new theory of network plasticity explains from a functional perspective a number of experimental data on stochastic aspects of synaptic plasticity that previously appeared to be quite puzzling. PMID:26545099

  16. WEATHERABILITY OF ENHANCED DEGRADABLE PLASTICS

    EPA Science Inventory

    The main objective of this study was to assess the performance and the asociated variability of several selected enhanced degradable plastic materials under a variety of different exposure conditions. Other objectives were to identify the major products formed during degradation ...

  17. Effects of focal ankle joint cooling on unipedal static balance in individuals with and without chronic ankle instability.

    PubMed

    Kim, Kyung-Min; Hart, Joseph M; Saliba, Susan A; Hertel, Jay

    2015-01-01

    Application of cryotherapy over an injured joint has been shown to improve muscle function, yet it is unknown how ankle cryotherapy affects postural control. Our purpose was to determine the effects of a 20-min focal ankle joint cooling on unipedal static stance in individuals with and without chronic ankle instability (CAI). Fifteen young subjects with CAI (9 males, 6 females) and 15 healthy gender-matched controls participated. All subjects underwent two intervention sessions on different days in which they had a 1.5L plastic bag filled with either crushed ice (active treatment) or candy corn (sham) applied to the ankle. Unipedal stance with eyes closed for 10s were assessed with a forceplate before and after each intervention. Center of pressure (COP) data were used to compute 10 specific dependent measures including velocity, area, standard deviation (SD), and percent range of COP excursions, and mean and SD of time-to-boundary (TTB) minima in the anterior-posterior (AP) and mediolateral directions. For each measure a three-way (Group-Intervention-Time) repeated ANOVAs found no significant interactions and main effects involving intervention (all Ps > 0.05). There were group main effects found for mean velocity (F(1,28) = 6.46, P = .017), area (F(1,28) = 12.83, P = .001), and mean of TTB minima in the AP direction (F(1,28) = 5.19, P = .031) indicating that the CAI group demonstrated greater postural instability compared to the healthy group. Postural control of unipedal stance was not significantly altered following focal ankle joint cooling in groups both with and without CAI. Ankle joint cryotherapy was neither beneficial nor harmful to single leg balance. PMID:25468685

  18. Nano-Ceramic Coated Plastics

    NASA Technical Reports Server (NTRS)

    Cho, Junghyun

    2013-01-01

    Plastic products, due to their durability, safety, and low manufacturing cost, are now rapidly replacing cookware items traditionally made of glass and ceramics. Despite this trend, some still prefer relatively expensive and more fragile ceramic/glassware because plastics can deteriorate over time after exposure to foods, which can generate odors, bad appearance, and/or color change. Nano-ceramic coatings can eliminate these drawbacks while still retaining the advantages of the plastic, since the coating only alters the surface of the plastic. The surface coating adds functionality to the plastics such as self-cleaning and disinfectant capabilities that result from a photocatalytic effect of certain ceramic systems. These ceramic coatings can also provide non-stick surfaces and higher temperature capabilities for the base plastics without resorting to ceramic or glass materials. Titanium dioxide (TiO2) and zinc oxide (ZnO) are the candidates for a nano-ceramic coating to deposit on the plastics or plastic films used in cookware and kitchenware. Both are wide-bandgap semiconductors (3.0 to 3.2 eV for TiO2 and 3.2 to 3.3 eV for ZnO), so they exhibit a photocatalytic property under ultraviolet (UV) light. This will lead to decomposition of organic compounds. Decomposed products can be easily washed off by water, so the use of detergents will be minimal. High-crystalline film with large surface area for the reaction is essential to guarantee good photocatalytic performance of these oxides. Low-temperature processing (<100 C) is also a key to generating these ceramic coatings on the plastics. One possible way of processing nanoceramic coatings at low temperatures (< 90 C) is to take advantage of in-situ precipitated nanoparticles and nanostructures grown from aqueous solution. These nanostructures can be tailored to ceramic film formation and the subsequent microstructure development. In addition, the process provides environment- friendly processing because of the

  19. Polygonal instabilities on interfacial vorticities.

    PubMed

    Labousse, M; Bush, J W M

    2015-10-01

    We report the results of a theoretical investigation of the stability of a toroidal vortex bound by an interface. Two distinct instability mechanisms are identified that rely on, respectively, surface tension and fluid inertia, either of which may prompt the transformation from a circular to a polygonal torus. Our results are discussed in the context of three experiments, a toroidal vortex ring, the hydraulic jump, and the hydraulic bump. PMID:26537726

  20. Combustion instability modeling and analysis

    SciTech Connect

    Santoro, R.J.; Yang, V.; Santavicca, D.A.; Sheppard, E.J.

    1995-12-31

    It is well known that the two key elements for achieving low emissions and high performance in a gas turbine combustor are to simultaneously establish (1) a lean combustion zone for maintaining low NO{sub x} emissions and (2) rapid mixing for good ignition and flame stability. However, these requirements, when coupled with the short combustor lengths used to limit the residence time for NO formation typical of advanced gas turbine combustors, can lead to problems regarding unburned hydrocarbons (UHC) and carbon monoxide (CO) emissions, as well as the occurrence of combustion instabilities. The concurrent development of suitable analytical and numerical models that are validated with experimental studies is important for achieving this objective. A major benefit of the present research will be to provide for the first time an experimentally verified model of emissions and performance of gas turbine combustors. The present study represents a coordinated effort between industry, government and academia to investigate gas turbine combustion dynamics. Specific study areas include development of advanced diagnostics, definition of controlling phenomena, advancement of analytical and numerical modeling capabilities, and assessment of the current status of our ability to apply these tools to practical gas turbine combustors. The present work involves four tasks which address, respectively, (1) the development of a fiber-optic probe for fuel-air ratio measurements, (2) the study of combustion instability using laser-based diagnostics in a high pressure, high temperature flow reactor, (3) the development of analytical and numerical modeling capabilities for describing combustion instability which will be validated against experimental data, and (4) the preparation of a literature survey and establishment of a data base on practical experience with combustion instability.

  1. Ben's Plastic Brain

    ERIC Educational Resources Information Center

    Kaplan, Susan L.

    2010-01-01

    This article shares a story of Ben who as a result of his premature birth, suffered a brain hemorrhage resulting in cerebral palsy, which affected his left side (left hemiparesis) and caused learning disabilities. Despite these challenges, he graduated from college and currently works doing information management for a local biotech start-up…

  2. Pattern Generation by Dissipative Parametric Instability

    NASA Astrophysics Data System (ADS)

    Perego, A. M.; Tarasov, N.; Churkin, D. V.; Turitsyn, S. K.; Staliunas, K.

    2016-01-01

    Nonlinear instabilities are responsible for spontaneous pattern formation in a vast number of natural and engineered systems, ranging from biology to galaxy buildup. We propose a new instability mechanism leading to pattern formation in spatially extended nonlinear systems, which is based on a periodic antiphase modulation of spectrally dependent losses arranged in a zigzag way: an effective filtering is imposed at symmetrically located wave numbers k and -k in alternating order. The properties of the dissipative parametric instability differ from the features of both key classical concepts of modulation instabilities, i.e., the Benjamin-Feir instability and the Faraday instabiltyity. We demonstrate how the dissipative parametric instability can lead to the formation of stable patterns in one- and two-dimensional systems. The proposed instability mechanism is generic and can naturally occur or can be implemented in various physical systems.

  3. Pattern Generation by Dissipative Parametric Instability.

    PubMed

    Perego, A M; Tarasov, N; Churkin, D V; Turitsyn, S K; Staliunas, K

    2016-01-15

    Nonlinear instabilities are responsible for spontaneous pattern formation in a vast number of natural and engineered systems, ranging from biology to galaxy buildup. We propose a new instability mechanism leading to pattern formation in spatially extended nonlinear systems, which is based on a periodic antiphase modulation of spectrally dependent losses arranged in a zigzag way: an effective filtering is imposed at symmetrically located wave numbers k and -k in alternating order. The properties of the dissipative parametric instability differ from the features of both key classical concepts of modulation instabilities, i.e., the Benjamin-Feir instability and the Faraday instabiltyity. We demonstrate how the dissipative parametric instability can lead to the formation of stable patterns in one- and two-dimensional systems. The proposed instability mechanism is generic and can naturally occur or can be implemented in various physical systems. PMID:26824573

  4. Microphysics of Cosmic Ray Driven Plasma Instabilities

    NASA Astrophysics Data System (ADS)

    Bykov, A. M.; Brandenburg, A.; Malkov, M. A.; Osipov, S. M.

    2013-10-01

    Energetic nonthermal particles (cosmic rays, CRs) are accelerated in supernova remnants, relativistic jets and other astrophysical objects. The CR energy density is typically comparable with that of the thermal components and magnetic fields. In this review we discuss mechanisms of magnetic field amplification due to instabilities induced by CRs. We derive CR kinetic and magnetohydrodynamic equations that govern cosmic plasma systems comprising the thermal background plasma, comic rays and fluctuating magnetic fields to study CR-driven instabilities. Both resonant and non-resonant instabilities are reviewed, including the Bell short-wavelength instability, and the firehose instability. Special attention is paid to the longwavelength instabilities driven by the CR current and pressure gradient. The helicity production by the CR current-driven instabilities is discussed in connection with the dynamo mechanisms of cosmic magnetic field amplification.

  5. Microphysics of Cosmic Ray Driven Plasma Instabilities

    NASA Astrophysics Data System (ADS)

    Bykov, A. M.; Brandenburg, A.; Malkov, M. A.; Osipov, S. M.

    Energetic nonthermal particles (cosmic rays, CRs) are accelerated in supernova remnants, relativistic jets and other astrophysical objects. The CR energy density is typically comparable with that of the thermal components and magnetic fields. In this review we discuss mechanisms of magnetic field amplification due to instabilities induced by CRs. We derive CR kinetic and magnetohydrodynamic equations that govern cosmic plasma systems comprising the thermal background plasma, comic rays and fluctuating magnetic fields to study CR-driven instabilities. Both resonant and non-resonant instabilities are reviewed, including the Bell short-wavelength instability, and the firehose instability. Special attention is paid to the longwavelength instabilities driven by the CR current and pressure gradient. The helicity production by the CR current-driven instabilities is discussed in connection with the dynamo mechanisms of cosmic magnetic field amplification.

  6. Nanoscale plasticity in silica glass

    SciTech Connect

    Glosli, J.N.; Boercker, D.B.; Tesar, A.; Belak, J.

    1993-10-01

    Mechanisms of nano-scale plasticity and damage initiation in silica glass is examined using molecular dynamics simulation. Computer experiments are carried out by indenting a sharp diamond-like tool, containing 4496 atoms, into a silica slab consisting of 12288 atoms. Both elastic and plastic deformation of silica is observed during nanoindentation simulation; this transition occurs at an indentation of 1.25 nm, and the calculated hardness (15GPa for 1.5 nm indentation) agrees with experiment.

  7. [Plasticity of the cellular phenotype].

    PubMed

    Chneiweiss, Hervé

    2011-01-01

    The tragical consequences of the Hiroshima and Nagasaki atomic bombs in 1945 were to lead to the discovery of hematopoietic stem cells and their phenotypic plasticity, in response to environmental factors. These concepts were much later extended to the founding cells of other tissues. In the following collection of articles, the mechanisms underlying this plasticity, at the frontiers of developmental biology and oncology, are illustrated in the case of various cell types of neural origin and of some tumours. PMID:21501574

  8. Helene: A Plastic Model

    NASA Astrophysics Data System (ADS)

    Umurhan, O. M.; Moore, J. M.; Howard, A. D.; Schenk, P.; White, O. L.

    2014-12-01

    Helene, the Saturnian L4 Trojan satellite co-orbiting Dionne and sitting within the E-ring, possesses an unusual morphology characteristic of broad km-scale basins and depressions and a generally smooth surface patterned with streaks and grooves which are indicative of non-typical mass transport. Elevation angles do not appear to exceed 10o at most. The nature and origin of the surface materials forming these grooved patterns is unknown. Given the low surface gravity (<5mm/s2), it hard to imagine how such transport features can come about with such low grades and surface gravities. Preliminary examinations of classical linear and nonlinear mass wasting mechanisms do not appear to reproduce these curious features. A suite of hypothesis that we examine is the possibility that the fine grain material on the surface has been either (i) accreted or (ii) generated as refractory detritus resulting from sublimation of the icy bedrock, and that these materials subsequently mass-waste like a non-Newtonian highly non-linear creeping flow. Modifying the landform evolution model MARSSIM to handle two new mass-wasting mechanism, the first due to glacial-like flow via Glen's Law and the second due to plastic-like flow like a Bingham fluid, we setup and test a number of likely scenarios to explain the observations. The numerical results qualitatively indicate that treating the mass-wasting materials as a Bingham material reproduces many of the qualitative features observed. We also find that in those simulations in which accretion is concomitant with Bingham mass-wasting, the long time-evolution of the surface flow shows intermittency in the total surface activity (defined as total surface integral of the absolute magnitude of the mass-flux). Detailed analyses identify the locations where this activity is most pronounced and we will discuss these and its implications in further detail.

  9. Migrational Instabilities in Particle Suspensions

    NASA Technical Reports Server (NTRS)

    Goddard, Joe D.

    1996-01-01

    This work deals with an instability arising from the shear-induced migration of particles in dense suspensions coupled with a dependence of viscosity on particle concentration. The analysis summarized here treats the inertialess (Re = O) linear stability of homogeneous simple shear flows for a Stokesian suspension model of the type proposed by Leighton and Acrivos (1987). Depending on the importance of shear-induced migration relative to concentration-driven diffusion, this model admits short-wave instability arising from wave-vector stretching by the base flow and evolving into particle-depleted shear bands. Moreover, this instability in the time-dependent problem corresponds to loss of ellipticity in the associated static problem (Re = O, Pe = O). While the isotropic version of the Leighton-Acrivos model is found to be stable with their experimentally determined parameters for simple shear, it is known that the stable model does not give a good quantitative description of particle clustering in the core of pipe flow (Nott and Brady 1994). This leads to the conjecture that an appropriate variant on the above model could explain such clustering as a two-phase bifurcation in the base flow.

  10. Plasticity effects in hydraulic fracturing

    SciTech Connect

    Medlin, W.L.; Masse, L.

    1986-09-01

    The importance of reservoir rock plasticity in fracturing operations has been investigated by laboratory experiments and field results. A Lagrangian formulation for crack propagation provided the basis for the laboratory experiments. A simple crack propagation experiment showed that plasticity effects can be observed and that the importance of plasticity depends on the relative magnitudes of surface energy and energy dissipated in plastic deformation of a reservoir rock. The latter can be evaluated by laboratory measurements of a plasticity coefficient, ..cap alpha.., which comes out of the Lagrangian analysis. To measure ..cap alpha.., the authors developed a triaxial system for applying tensile stress to rock cores under confining pressure at strain rates characteristic of fracturing operations. Strain gauges mounted on each core were used with a servo-controlled press to apply strain at a linear rate between 10/sup -4/ and 10/sup -6/ seconds /sup -1/ and to obtain stress/strain data to the point of tensile failure. To distinguish between plasticity and nonlinear elastic phenomena, the authors also obtained strain hysteresis data.

  11. Transmission laser welding of plastics

    NASA Astrophysics Data System (ADS)

    Hilton, Paul A.; Jones, I. A.; Kennish, Y.

    2003-03-01

    The use of lasers for welding plastics was demonstrated in the early 1970s. However, it was not until late in the 1990s that production applications started to be considered widely. This followed the broad realization that by selection of a suitable combination of radiation wavelength and plastics additives, to control light transmission and absorption, heat could be generated at the joint of a pre-assembled part without melting its outer surfaces. It is of added benefit that the window of transmission for an unpigmented and unfilled plastic typically covers the wavelengths delivered by small and cost effective diode lasers. Recent developments in the transmission laser welding process for plastics are discussed, including methods for the generation of welds between two clear plastics, application of similar techniques to the joining of thermoplastic textiles and new equipment, able to heat a complete joint and assist in the sealing of assemblies where the joint surfaces are not particuarly smooth. An analytical heat flow model for the welding of clear plastics is shown in use for selecting process parameters.

  12. High prevalence of parental delivery of plastic debris in Cory's shearwaters (Calonectris diomedea).

    PubMed

    Rodríguez, Airam; Rodríguez, Beneharo; Nazaret Carrasco, María

    2012-10-01

    Plastic ingestion by adult Procellariiformes has been widely recorded, but few studies have evaluated intergenerational transfer. We assessed the prevalence of plastic particles, as well as their basic characteristics, in the gut content of dead Cory's shearwater fledglings stranded by light pollution on Canary Islands. Eighty-three percent of birds were affected, containing on average 8.0 plastic pieces per bird. The average plastic weight per bird was low (2.97±3.97mg) compared with other petrel species. We found no relationships between plastic loads and body condition or body size, but negative effects may be hidden or delayed. We propose to use the fledglings stranded by light pollution to carry out more precise studies to understand the potential hidden costs of plastic ingestion; and to monitor in a long-term the marine debris to develop management actions for the control of pollution at the marine environment. PMID:22784377

  13. Early depolarizing GABA controls critical period plasticity in the rat visual cortex

    PubMed Central

    Deidda, Gabriele; Allegra, Manuela; Cerri, Chiara; Naskar, Shovan; Bony, Guillaume; Zunino, Giulia; Bozzi, Yuri; Caleo, Matteo; Cancedda, Laura

    2014-01-01

    SUMMARY Hyperpolarizing and inhibitory GABA regulates “critical periods” for plasticity in sensory cortices. Here, we examine the role of early, depolarizing GABA in controlling plasticity mechanisms. We report that brief interference with depolarizing GABA during early development prolonged critical period plasticity in visual cortical circuits, without affecting overall development of the visual system. The effects on plasticity were accompanied by dampened inhibitory neurotransmission, down-regulation of BDNF expression, and reduced density of extracellular matrix-perineuronal nets. Early interference with depolarizing GABA decreased perinatal BDNF signaling, and pharmacological increase of BDNF signaling during GABA interference rescued the effects on plasticity and its regulators later in life. We conclude that depolarizing GABA exerts a long-lasting, selective modulation of plasticity of cortical circuits by a strong crosstalk with BDNF. PMID:25485756

  14. 49 CFR 178.925 - Standards for rigid plastic Large Packagings.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... to § 173.24 of this subchapter, plastic materials must be resistant to aging and to degradation... the resistance to aging or to serve other purposes, provided they do not adversely affect the...

  15. Hysteresis in the creasing instability of hydrogels and elastomers

    NASA Astrophysics Data System (ADS)

    Chen, Dayong; Cai, Shengqiang; Jin, Lihua; Suo, Zhigang; Hayward, Ryan

    2013-03-01

    Soft polymers placed under compressive stress can undergo an elastic creasing instability in which sharp folds spontaneously form on the free surfaces. This process can play an important role in a variety of material failure modes, but has also been harnessed to fabricate dynamic chemical and topographic patterns. Creases have been found to form by nucleation and growth, which we show reflects the influence of surface energy as a barrier for both processes. Hysteresis in the loading and unloading cycles is an important aspect of this process, but has been reported to occur to different degrees in different material systems. Through variations in interfacial energy, we show that for a model elastomeric system, it is self-adhesion within the folding region rather than plastic deformation that gives rise to hysteresis.

  16. Current driven instabilities of an electromagnetically accelerated plasma

    NASA Technical Reports Server (NTRS)

    Chouetri, E. Y.; Kelly, A. J.; Jahn, R. G.

    1988-01-01

    A plasma instability that strongly influences the efficiency and lifetime of electromagnetic plasma accelerators was quantitatively measured. Experimental measurements of dispersion relations (wave phase velocities), spatial growth rates, and stability boundaries are reported. The measured critical wave parameters are in excellent agreement with theoretical instability boundary predictions. The instability is current driven and affects a wide spectrum of longitudinal (electrostatic) oscillations. Current driven instabilities, which are intrinsic to the high-current-carrying magnetized plasma of the magnetoplasmadynmic (MPD) accelerator, were investigated with a kinetic theoretical model based on first principles. Analytical limits of the appropriate dispersion relation yield unstable ion acoustic waves for T(i)/T(e) much less than 1 and electron acoustic waves for T(i)/T(e) much greater than 1. The resulting set of nonlinear equations for the case of T(i)/T(e) = 1, of most interest to the MPD thruster Plasma Wave Experiment, was numerically solved to yield a multiparameter set of stability boundaries. Under certain conditions, marginally stable waves traveling almost perpendicular to the magnetic field would travel at a velocity equal to that of the electron current. Such waves were termed current waves. Unstable current waves near the upper stability boundary were observed experimentally and are in accordance with theoretical predictions. This provides unambiguous proof of the existence of such instabilites in electromagnetic plasma accelerators.

  17. Beam-Plasma Instabilities in Strongly Coupled Plasmas

    NASA Astrophysics Data System (ADS)

    Kalman, Gabor J.; Rosenberg, Marlene

    2001-10-01

    Strongly coupled dusty plasmas under laboratory conditions are permeated by streaming ions: in this scenario beam- plasma instabilities may be excited. The strong coupling between the dust grains, however, fundamentally affects the condition for instability and renders the conventional Vlasov treatment entirely inadequate. Based on the Quasilocalized Charge Approximation [1,2,3] we develop an analysis of instabilities generated by the relative streaming of a weakly coupled and a strongly coupled plasma. The central role in this formalism is played by the Dynamical Matrix D(k), a functional of the equilibrium correlation function, determined in our earlier work [2,3]. Novel physical effects generated by strong coupling alter both the beam resonance condition and the coupling between the beam and the plasma modes. Our analysis covers both resonant and non-resonant, as well as resistive instabilities. [1] Kenneth I. Golden and Gabor J. Kalman, Phys. Plasmas, 7, 14 (2000) [2] M. Rosenberg and G. Kalman, Phys. Rev. E 56, 7166 (1997) [3] G. Kalman, M.Rosenberg and H. E. DeWitt, Phys. Rev Lett. 84, 6030 (2000)

  18. On the identification of instabilities with neural networks on JET

    NASA Astrophysics Data System (ADS)

    Murari, A.; Arena, P.; Buscarino, A.; Fortuna, L.; Iachello, M.

    2013-08-01

    JET plasmas are affected by various instabilities, which can be particularly dangerous in high performance discharges. An identification method, based on the use of advanced neural networks, called Recurrent Neural Networks (RNNs), has been applied to ELMs. The potential of the recurrent networks to identify the dynamics of the instabilities has been first tested using synthetic data. The networks have then been applied to JET experimental signals. An appropriate selection of the networks topology allows identifying quite well the time evolution of the edge temperature and of the magnetic fields, considered the best indicators of the ELMs. A quite limited number of periodic oscillations are used to train the networks, which then manage to follow quite well the dynamics of the instabilities, in a recurrent configuration on one of the inputs. The time evolution of the aforementioned signals, also during intervals not used in the training and never seen by the networks, are properly reproduced. A careful analysis of the various terms in the RNNs has the potential to give clear indications about the nature of these instabilities and their dynamical behaviour.

  19. Dielectric permittivity tensor and low frequency instabilities of a magnetoactive current-driven plasma with nonextensive distribution

    SciTech Connect

    Niknam, A. R.; Rastbood, E.; Khorashadizadeh, S. M.

    2015-12-15

    The dielectric permittivity tensor of a magnetoactive current-driven plasma is obtained by employing the kinetic theory based on the Vlasov equation and Lorentz transformation formulas with an emphasize on the q-nonextensive statistics. By deriving the q-generalized dispersion relation of the low frequency modes in this plasma system, the possibility and properties of filamentation and ion acoustic instabilities are then studied. It is shown that the occurrence and the growth rate of these instabilities depend strongly on the nonextensive parameters, external magnetic field strength, and drift velocity. It is observed that the growth rate of ion acoustic instability is affected by the magnetic field strength much more than that of the filamentation instability in the low frequency range. The external magnetic field facilitates the development of the ion-acoustic instability. It is also shown that the filamentation is the dominant instability only for the high value of drift velocity.

  20. 49 CFR 192.59 - Plastic pipe.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 3 2011-10-01 2011-10-01 false Plastic pipe. 192.59 Section 192.59 Transportation... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Materials § 192.59 Plastic pipe. (a) New plastic pipe... specification; and (2) It is resistant to chemicals with which contact may be anticipated. (b) Used plastic...