Sample records for agc technology work

  1. The wheat AGC kinase TaAGC1 is a positive contributor to host resistance to the necrotrophic pathogen Rhizoctonia cerealis.

    PubMed

    Zhu, Xiuliang; Yang, Kun; Wei, Xuening; Zhang, Qiaofeng; Rong, Wei; Du, Lipu; Ye, Xingguo; Qi, Lin; Zhang, Zengyan

    2015-11-01

    Considerable progress has been made in understanding the roles of AGC kinases in mammalian systems. However, very little is known about the roles of AGC kinases in wheat (Triticum aestivum). The necrotrophic fungus Rhizoctonia cerealis is the major pathogen of the destructive disease sharp eyespot of wheat. In this study, the wheat AGC kinase gene TaAGC1, responding to R. cerealis infection, was isolated, and its properties and role in wheat defence were characterized. R. cerealis-resistant wheat lines expressed TaAGC1 at higher levels than susceptible wheat lines. Sequence and phylogenetic analyses showed that the TaAGC1 protein is a serine/threonine kinase belonging to the NDR (nuclear Dbf2-related) subgroup of AGC kinases. Kinase activity assays proved that TaAGC1 is a functional kinase and the Asp-239 residue located in the conserved serine/threonine kinase domain of TaAGC1 is required for the kinase activity. Subcellular localization assays indicated that TaAGC1 localized in the cytoplasm and nucleus. Virus-induced TaAGC1 silencing revealed that the down-regulation of TaAGC1 transcripts significantly impaired wheat resistance to R. cerealis. The molecular characterization and responses of TaAGC1 overexpressing transgenic wheat plants indicated that TaAGC1 overexpression significantly enhanced resistance to sharp eyespot and reduced the accumulation of reactive oxygen species (ROS) in wheat plants challenged with R. cerealis. Furthermore, ROS-scavenging and certain defence-associated genes were up-regulated in resistant plants overexpressing TaAGC1 but down-regulated in susceptible knock-down plants. These results suggested that the kinase TaAGC1 positively contributes to wheat immunity to R. cerealis through regulating expression of ROS-related and defence-associated genes. © The Author 2015. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  2. The wheat AGC kinase TaAGC1 is a positive contributor to host resistance to the necrotrophic pathogen Rhizoctonia cerealis

    PubMed Central

    Zhu, Xiuliang; Yang, Kun; Wei, Xuening; Zhang, Qiaofeng; Rong, Wei; Du, Lipu; Ye, Xingguo; Qi, Lin; Zhang, Zengyan

    2015-01-01

    Considerable progress has been made in understanding the roles of AGC kinases in mammalian systems. However, very little is known about the roles of AGC kinases in wheat (Triticum aestivum). The necrotrophic fungus Rhizoctonia cerealis is the major pathogen of the destructive disease sharp eyespot of wheat. In this study, the wheat AGC kinase gene TaAGC1, responding to R. cerealis infection, was isolated, and its properties and role in wheat defence were characterized. R. cerealis-resistant wheat lines expressed TaAGC1 at higher levels than susceptible wheat lines. Sequence and phylogenetic analyses showed that the TaAGC1 protein is a serine/threonine kinase belonging to the NDR (nuclear Dbf2-related) subgroup of AGC kinases. Kinase activity assays proved that TaAGC1 is a functional kinase and the Asp-239 residue located in the conserved serine/threonine kinase domain of TaAGC1 is required for the kinase activity. Subcellular localization assays indicated that TaAGC1 localized in the cytoplasm and nucleus. Virus-induced TaAGC1 silencing revealed that the down-regulation of TaAGC1 transcripts significantly impaired wheat resistance to R. cerealis. The molecular characterization and responses of TaAGC1 overexpressing transgenic wheat plants indicated that TaAGC1 overexpression significantly enhanced resistance to sharp eyespot and reduced the accumulation of reactive oxygen species (ROS) in wheat plants challenged with R. cerealis. Furthermore, ROS-scavenging and certain defence-associated genes were up-regulated in resistant plants overexpressing TaAGC1 but down-regulated in susceptible knock-down plants. These results suggested that the kinase TaAGC1 positively contributes to wheat immunity to R. cerealis through regulating expression of ROS-related and defence-associated genes. PMID:26220083

  3. PRELIMINARY RESULTS OF THE AGC-4 IRRADIATION IN THE ADVANCED TEST REACTOR AND DESIGN OF AGC-5 (HTR16-18469)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davenport, Michael; Petti, D. A.

    The United States Department of Energy’s Advanced Reactor Technologies (ART) Program will irradiate up to six nuclear graphite creep experiments in the Advanced Test Reactor (ATR) located at the Idaho National Laboratory (INL). The graphite experiments are being irradiated over an approximate eight year period to support development of a graphite irradiation performance data base on the new nuclear grade graphites now available for use in high temperature gas reactors. The goals of the irradiation experiments are to obtain irradiation performance data, including irradiation creep, at different temperatures and loading conditions to support design of the Very High Temperature Gasmore » Reactor (VHTR), as well as other future gas reactors. The experiments each consist of a single capsule that contain six stacks of graphite specimens, with half of the graphite specimens in each stack under a compressive load, while the other half of the specimens are not be subjected to a compressive load during irradiation. The six stacks have differing compressive loads applied to the top half of diametrically opposite pairs of specimen stacks. A seventh specimen stack in the center of the capsule does not have a compressive load. The specimens are being irradiated in an inert sweep gas atmosphere with on-line temperature and compressive load monitoring and control. There are also samples taken of the sweep gas effluent to measure any oxidation or off-gassing of the specimens that may occur during initial start-up of the experiment. The first experiment, AGC-1, started its irradiation in September 2009, and the irradiation was completed in January 2011. The second experiment, AGC-2, started its irradiation in April 2011 and completed its irradiation in May 2012. The third experiment, AGC-3, started its irradiation in late November 2012 and completed in the April of 2014. AGC-4 is currently being irradiated in the ATR. This paper will briefly discuss the preliminary irradiation

  4. Is AGC beneficial in hearing aids?

    PubMed

    King, A B; Martin, M C

    1984-02-01

    Three different functions of Automatic Gain Control (AGC) circuits in hearing aids are distinguished and the evidence for their benefits is considered. The value of AGC's function as a relatively distortion-free means of limiting output has been well established. With regard to compression, the benefit of short-term or 'syllabic' compression has not been demonstrated convincingly. Most evaluations of this type of AGC have looked for increase in speech intelligibility, but theoretical predictions of its effect do not appear to take account of the acoustic cues to consonant contrasts actually used by hearing impaired people, and empirical studies have often used listening conditions which do not give a realistic test of benefit. Relatively little attention has been paid to long-term compression, or to the effect of AGC on comfort rather than intelligibility. Listening tests carried out at the RNID and reported here have shown that AGC can benefit hearing aid users by allowing them to listen to a wider range of sound levels without either strain or discomfort, and, if time constants are well chosen, without adverse effects on speech intelligibility in quiet or in noise.

  5. A Robust Distributed Multipoint Fiber Optic Gas Sensor System Based on AGC Amplifier Structure.

    PubMed

    Zhu, Cunguang; Wang, Rende; Tao, Xuechen; Wang, Guangwei; Wang, Pengpeng

    2016-07-28

    A harsh environment-oriented distributed multipoint fiber optic gas sensor system realized by automatic gain control (AGC) technology is proposed. To improve the photoelectric signal reliability, the electronic variable gain can be modified in real time by an AGC closed-loop feedback structure to compensate for optical transmission loss which is caused by the fiber bend loss or other reasons. The deviation of the system based on AGC structure is below 4.02% when photoelectric signal decays due to fiber bending loss for bending radius of 5 mm, which is 20 times lower than the ordinary differential system. In addition, the AGC circuit with the same electric parameters can keep the baseline intensity of signals in different channels of the distributed multipoint sensor system at the same level. This avoids repetitive calibrations and streamlines the installation process.

  6. AGC-2 Graphite Pre-irradiation Data Package

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    David Swank; Joseph Lord; David Rohrbaugh

    2010-08-01

    The NGNP Graphite R&D program is currently establishing the safe operating envelope of graphite core components for a Very High Temperature Reactor (VHTR) design. The program is generating quantitative data necessary for predicting the behavior and operating performance of the new nuclear graphite grades. To determine the in-service behavior of the graphite for pebble bed and prismatic designs, the Advanced Graphite Creep (AGC) experiment is underway. This experiment is examining the properties and behavior of nuclear grade graphite over a large spectrum of temperatures, neutron fluences and compressive loads. Each experiment consists of over 400 graphite specimens that are characterizedmore » prior to irradiation and following irradiation. Six experiments are planned with the first, AGC-1, currently being irradiated in the Advanced Test Reactor (ATR) and pre-irradiation characterization of the second, AGC-2, completed. This data package establishes the readiness of 512 specimens for assembly into the AGC-2 capsule.« less

  7. AGC-2 Specimen Post Irradiation Data Package Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Windes, William Enoch; Swank, W. David; Rohrbaugh, David T.

    This report documents results of the post-irradiation examination material property testing of the creep, control, and piggyback specimens from the irradiation creep capsule Advanced Graphite Creep (AGC)-2 are reported. This is the second of a series of six irradiation test trains planned as part of the AGC experiment to fully characterize the neutron irradiation effects and radiation creep behavior of current nuclear graphite grades. The AGC-2 capsule was irradiated in the Idaho National Laboratory Advanced Test Reactor at a nominal temperature of 600°C and to a peak dose of 5 dpa (displacements per atom). One-half of the creep specimens weremore » subjected to mechanical stresses (an applied stress of either 13.8, 17.2, or 20.7 MPa) to induce irradiation creep. All post-irradiation testing and measurement results are reported with the exception of the irradiation mechanical strength testing, which is the last destructive testing stage of the irradiation testing program. Material property tests were conducted on specimens from 15 nuclear graphite grades using a similar loading configuration as the first AGC capsule (AGC-1) to provide easy comparison between the two capsules. However, AGC-2 contained an increased number of specimens (i.e., 487 total specimens irradiated) and replaced specimens of the minor grade 2020 with the newer grade 2114. The data reported include specimen dimensions for both stressed and unstressed specimens to establish the irradiation creep rates, mass and volume data necessary to derive density, elastic constants (Young’s modulus, shear modulus, and Poisson’s ratio) from ultrasonic time-of-flight velocity measurements, Young’s modulus from the fundamental frequency of vibration, electrical resistivity, and thermal diffusivity and thermal expansion data from 100–500°C. No data outliers were determined after all measurements were completed. A brief statistical analysis was performed on the irradiated data and a limited comparison

  8. Myotonin protein-kinase [AGC]n trinucleotide repeat in seven nonhuman primates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Novelli, G.; Sineo, L.; Pontieri, E.

    Myotonic dystrophy (DM) is due to a genomic instability of a trinucleotide [AGC]n motif, located at the 3{prime} UTR region of a protein-kinase gene (myotonin protein kinase, MT-PK). The [AGC] repeat is meiotically and mitotically unstable, and it is directly related to the manifestations of the disorder. Although a gene dosage effect of the MT-PK has been demonstrated n DM muscle, the mechanism(s) by which the intragenic repeat expansion leads to disease is largely unknown. This non-standard mutational event could reflect an evolutionary mechanism widespread among animal genomes. We have isolated and sequenced the complete 3{prime}UTR region of the MT-PKmore » gene in seven primates (macaque, orangutan, gorilla, chimpanzee, gibbon, owl monkey, saimiri), and examined by comparative sequence nucleotide analysis the [AGC]n intragenic repeat and the surrounding nucleotides. The genomic organization, including the [AGC]n repeat structure, was conserved in all examined species, excluding the gibbon (Hylobates agilis), in which the [AGC]n upstream sequence (GGAA) is replaced by a GA dinucleotide. The number of [AGC]n in the examined species ranged between 7 (gorilla) and 13 repeats (owl monkeys), with a polymorphism informative content (PIC) similar to that observed in humans. These results indicate that the 3{prime}UTR [AGC] repeat within the MT-PK gene is evolutionarily conserved, supporting that this region has important regulatory functions.« less

  9. Dwarfism in homozygous Agc1CreERT mice is associated with decreased expression of aggrecan.

    PubMed

    Rashid, Harunur; Chen, Haiyan; Hassan, Quamarul; Javed, Amjad

    2017-10-01

    Aggrecan (Acan), a large proteoglycan is abundantly expressed in cartilage tissue. Disruption of Acan gene causes dwarfism and perinatal lethality of homozygous mice. Because of sustained expression of Acan in the growth plate and articular cartilage, Agc Cre model has been developed for the regulated ablation of target gene in chondrocytes. In this model, the IRES-CreERT-Neo-pgk transgene is knocked-in the 3'UTR of the Acan gene. We consistently noticed variable weight and size among the Agc Cre littermates, prompting us to examine the cause of this phenotype. Wild-type, Cre-heterozygous (Agc +/Cre ), and Cre-homozygous (Agc Cre/Cre ) littermates were indistinguishable at birth. However, by 1-month, Agc Cre/Cre mice showed a significant reduction in body weight (18-27%) and body length (19-22%). Low body weight and dwarfism was sustained through adulthood and occurred in both genders. Compared with wild-type and Agc +/Cre littermates, long bones and vertebrae were shorter in Agc Cre/Cre mice. Histological analysis of Agc Cre/Cre mice revealed a significant reduction in the length of the growth plate and the thickness of articular cartilage. The amount of proteoglycan deposited in the cartilage of Agc Cre/Cre mice was nearly half of the WT littermates. Analysis of gene expression indicates impaired differentiation of chondrocyte in hyaline cartilage of Agc Cre/Cre mice. Notably, both Acan mRNA and protein was reduced by 50% in Agc Cre/Cre mice. A strong correlation was noted between the level of Acan mRNA and the body length. Importantly, Agc +/Cre mice showed no overt skeletal phenotype. Thus to avoid misinterpretation of data, only the Agc +/Cre mice should be used for conditional deletion of a target gene in the cartilage tissue. © 2017 Wiley Periodicals, Inc.

  10. The Numerical Studies Program for the Atmospheric General Circulation Experiment (AGCE) for Spacelab Flights

    NASA Technical Reports Server (NTRS)

    Fowlis, W. W. (Editor); Davis, M. H. (Editor)

    1981-01-01

    The atmospheric general circulation experiment (AGCE) numerical design for Spacelab flights was studied. A spherical baroclinic flow experiment which models the large scale circulations of the Earth's atmosphere was proposed. Gravity is simulated by a radial dielectric body force. The major objective of the AGCE is to study nonlinear baroclinic wave flows in spherical geometry. Numerical models must be developed which accurately predict the basic axisymmetric states and the stability of nonlinear baroclinic wave flows. A three dimensional, fully nonlinear, numerical model and the AGCE based on the complete set of equations is required. Progress in the AGCE numerical design studies program is reported.

  11. August gamma Cepheids (523-AGC)

    NASA Astrophysics Data System (ADS)

    Roggemans, Paul

    2018-02-01

    Favorable weather conditions between 19 August and 5 September 2017 enabled the CAMS BeNeLux network to collect 3189 orbits. A radiant concentration was spotted which was identified as the August gamma Cepheids (523-AGC). An independent search on a selection from all available meteor orbit lists coming from the suspect radiant area and velocity range was made. This resulted in 283 similar orbits, radiating from R.A. 358.4° and Decl. +76.2° with a geocentric velocity of 43.7 km/s in a time lapse between 146° and 165° in solar longitude with best activity at 155.7°. The orbital elements match perfectly with previously published results. There is no indication for any periodicity in the shower displays from year to year. The AGC-meteors are remarkably rich in bright meteors and rather deficient in faint meteors. Being detected independently from orbital data collected by different video networks, confirmed by 283 orbits with a medium threshold D criterion DD < 0.08 and 125 orbits with a high threshold of DD < 0.04, this minor shower could be considered to be listed as an established meteor shower.

  12. Hubble Space Telescope Imaging of the Ultra-compact High Velocity Cloud AGC 226067: A Stripped Remnant in the Virgo Cluster

    NASA Astrophysics Data System (ADS)

    Sand, D. J.; Seth, A. C.; Crnojević, D.; Spekkens, K.; Strader, J.; Adams, E. A. K.; Caldwell, N.; Guhathakurta, P.; Kenney, J.; Randall, S.; Simon, J. D.; Toloba, E.; Willman, B.

    2017-07-01

    We analyze the optical counterpart to the ultra-compact high velocity cloud AGC 226067, utilizing imaging taken with the Advanced Camera for Surveys (ACS) on the Hubble Space Telescope. The color-magnitude diagram of the main body of AGC 226067 reveals an exclusively young stellar population, with an age of ˜7-50 Myr, and is consistent with a metallicity of [Fe/H] ˜ -0.3 as previous work has measured via H II region spectroscopy. Additionally, the color-magnitude diagram is consistent with a distance of D ≈ 17 Mpc, suggesting an association with the Virgo cluster. A secondary stellar system located ˜1.‧6 (˜8 kpc) away in projection has a similar stellar population. The lack of an old red giant branch (≳5 Gyr) is contrasted with a serendipitously discovered Virgo dwarf in the ACS field of view (Dw J122147+132853), and the total diffuse light from AGC 226067 is consistent with the luminosity function of the resolved ˜7-50 Myr stellar population. The main body of AGC 226067 has a M V = -11.3 ± 0.3, or M stars = 5.4 ± 1.3 × 104 M ⊙ given the stellar population. We searched 20 deg2 of imaging data adjacent to AGC 226067 in the Virgo Cluster, and found two similar stellar systems dominated by a blue stellar population, far from any massive galaxy counterpart—if this population has star-formation properties that are similar to those of AGC 226067, it implies ˜0.1 M ⊙ yr-1 in Virgo intracluster star formation. Given its unusual stellar population, AGC 226067 is likely a stripped remnant and is plausibly the result of compressed gas from the ram pressure stripped M86 subgroup (˜350 kpc away in projection) as it falls into the Virgo Cluster.

  13. A sensitive glucose biosensor based on Ag@C core-shell matrix.

    PubMed

    Zhou, Xuan; Dai, Xingxin; Li, Jianguo; Long, Yumei; Li, Weifeng; Tu, Yifeng

    2015-04-01

    Nano-Ag particles were coated with colloidal carbon (Ag@C) to improve its biocompatibility and chemical stability for the preparation of biosensor. The core-shell structure was evidenced by transmission electron microscope (TEM) and the Fourier transfer infrared (FTIR) spectra revealed that the carbon shell is rich of function groups such as -OH and -COOH. The as-prepared Ag@C core-shell structure can offer favorable microenvironment for immobilizing glucose oxidase and the direct electrochemistry process of glucose oxidase (GOD) at Ag@C modified glassy carbon electrode (GCE) was realized. The modified electrode exhibited good response to glucose. Under optimum experimental conditions the biosensor linearly responded to glucose concentration in the range of 0.05-2.5mM, with a detection limit of 0.02mM (S/N=3). The apparent Michaelis-Menten constant (KM(app)) of the biosensor is calculated to be 1.7mM, suggesting high enzymatic activity and affinity toward glucose. In addition, the GOD-Ag@C/Nafion/GCE shows good reproducibility and long-term stability. These results suggested that core-shell structured Ag@C is an ideal matrix for the immobilization of the redox enzymes and further the construction of the sensitive enzyme biosensor. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. A Plan for Advanced Guidance and Control Technology for 2nd Generation Reusable Launch Vehicles

    NASA Technical Reports Server (NTRS)

    Hanson, John M.; Fogle, Frank (Technical Monitor)

    2002-01-01

    Advanced guidance and control (AG&C) technologies are critical for meeting safety/reliability and cost requirements for the next generation of reusable launch vehicle (RLV). This becomes clear upon examining the number of expendable launch vehicle failures in the recent past where AG&C technologies would have saved a RLV with the same failure mode, the additional vehicle problems where this technology applies, and the costs associated with mission design with or without all these failure issues. The state-of-the-art in guidance and control technology, as well as in computing technology, is at the point where we can took to the possibility of being able to safely return a RLV in any situation where it can physically be recovered. This paper outlines reasons for AG&C, current technology efforts, and the additional work needed for making this goal a reality.

  15. Hubble Space Telescope Imaging of the Ultra-compact High Velocity Cloud AGC 226067: A Stripped Remnant in the Virgo Cluster

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sand, D. J.; Crnojević, D.; Seth, A. C.

    We analyze the optical counterpart to the ultra-compact high velocity cloud AGC 226067, utilizing imaging taken with the Advanced Camera for Surveys (ACS) on the Hubble Space Telescope . The color–magnitude diagram of the main body of AGC 226067 reveals an exclusively young stellar population, with an age of ∼7–50 Myr, and is consistent with a metallicity of [Fe/H] ∼ −0.3 as previous work has measured via H ii region spectroscopy. Additionally, the color–magnitude diagram is consistent with a distance of D ≈ 17 Mpc, suggesting an association with the Virgo cluster. A secondary stellar system located ∼1.′6 (∼8 kpc)more » away in projection has a similar stellar population. The lack of an old red giant branch (≳5 Gyr) is contrasted with a serendipitously discovered Virgo dwarf in the ACS field of view (Dw J122147+132853), and the total diffuse light from AGC 226067 is consistent with the luminosity function of the resolved ∼7–50 Myr stellar population. The main body of AGC 226067 has a M {sub V} = −11.3 ± 0.3, or M {sub stars} = 5.4 ± 1.3 × 10{sup 4} M {sub ⊙} given the stellar population. We searched 20 deg{sup 2} of imaging data adjacent to AGC 226067 in the Virgo Cluster, and found two similar stellar systems dominated by a blue stellar population, far from any massive galaxy counterpart—if this population has star-formation properties that are similar to those of AGC 226067, it implies ∼0.1 M {sub ⊙} yr{sup −1} in Virgo intracluster star formation. Given its unusual stellar population, AGC 226067 is likely a stripped remnant and is plausibly the result of compressed gas from the ram pressure stripped M86 subgroup (∼350 kpc away in projection) as it falls into the Virgo Cluster.« less

  16. AGC-4 Experiment Irradiation Monitoring Data Qualification Interim Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hull, Laurence Charles

    2016-08-01

    The Graphite Technology Development Program is running a series of six experiments to quantify the effects of irradiation on nuclear grade graphite. The fourth experiment, Advanced Graphite Creep 4 (AGC 4), began with Advanced Test Reactor (ATR) cycle 157D on May 30, 2015, and has been irradiated for two cycles. The capsule was removed from the reactor after ATR cycle 158A, which ended on January 2, 2016, due to interference with another experiment. Irradiation will resume when the interfering experiment is removed from the reactor. This report documents qualification of AGC 4 experiment irradiation monitoring data for use by themore » Advanced Reactor Technologies (ART) Technology Development Office (TDO) Program for research and development activities required to design and license the first HTR nuclear plant. Qualified data meet the requirements for use as described in the experiment planning and quality assurance documents. Failed data do not meet the requirements and provide no useable information. Trend data may not meet all requirements, but still provide some useable information. Use of Trend data requires assessment of how any deficiencies affect a particular use of the data. All thermocouples (TCs) have functioned throughout the AGC-4 experiment. All temperature data are Qualified for use by the ART TDO Program. Argon, helium, and total gas flow data were within expected ranges and are Qualified for use by the ART TDO Program. Discharge gas line moisture values were consistently low during cycle 157D. At the start of cycle 158A, gas moisture briefly spiked to over 600 ppmv and then declined throughout the cycle. Moisture values are within the measurement range of the instrument and are Qualified for use by the ART TDO Program. Graphite creep specimens were subjected to one of three loads, 393, 491, or 589 lbf. For a brief period during cycle 157D between 12:19 on June 2, 2015 and 08:23 on June 11, 2015 the load cells were wired incorrectly resulting in

  17. ALFALFA DISCOVERY OF THE MOST METAL-POOR GAS-RICH GALAXY KNOWN: AGC 198691

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hirschauer, Alec S.; Salzer, John J.; Rhode, Katherine L., E-mail: ash@astro.indiana.edu, E-mail: slaz@astro.indiana.edu, E-mail: krhode@indiana.edu

    We present spectroscopic observations of the nearby dwarf galaxy AGC 198691. This object is part of the Survey of H i in Extremely Low-Mass Dwarfs project, which is a multi-wavelength study of galaxies with H i masses in the range of 10{sup 6}–10{sup 7.2} M {sub ⊙}, discovered by the Arecibo Legacy Fast ALFA (ALFALFA) survey. We have obtained spectra of the lone H ii region in AGC 198691 with the new high-throughput KPNO Ohio State Multi-Object Spectrograph on the Mayall 4 m, as well as with the Blue Channel spectrograph on the MMT 6.5 m telescope. These observations enablemore » the measurement of the temperature-sensitive [O iii] λ 4363 line and hence the determination of a “direct” oxygen abundance for AGC 198691. We find this system to be an extremely metal-deficient (XMD) system with an oxygen abundance of 12+log(O/H) = 7.02 ± 0.03, making AGC 198691 the lowest-abundance star-forming galaxy known in the local universe. Two of the five lowest-abundance galaxies known have been discovered by the ALFALFA blind H i survey; this high yield of XMD galaxies represents a paradigm shift in the search for extremely metal-poor galaxies.« less

  18. HST Imaging of the (Almost) Dark ALFALFA Source AGC 229385

    NASA Astrophysics Data System (ADS)

    Brunker, Samantha; Salzer, John Joseph; McQuinn, Kristen B.; Janowiecki, Steven; Leisman, Luke; Rhode, Katherine L.; Adams, Elizabeth A.; Cannon, John M.; Giovanelli, Riccardo; Haynes, Martha P.

    2017-06-01

    We present deep HST imaging photometry of the extreme galaxy AGC 229385. This system was first discovered as an HI source in the ALFALFA all-sky HI survey. It was cataloged as an (almost) dark galaxy because it did not exhibit any obvious optical counterpart in the available wide-field survey data (e.g., SDSS). Deep optical imaging with the WIYN 3.5-m telescope revealed an ultra-low surface brightness stellar component located at the center of the HI detection. With a peak central surface brightness of 26.4 mag/sq. arcsec in g and very blue colors (g-r = -0.1), the stellar component to this gas-rich system is quite enigmatic. We have used our HST images to produce a deep CMD of the resolved stellar population present in AGC 229385. We clearly detect a red-giant branch and use it to infer a distance of 5.50 ± 0.23 Mpc. The CMD is dominated by older stars, contrary to expectations given the blue optical colors obtained from our ground-based photometry. Our new distance is substantially lower than earlier estimates, and shows that AGC 229385 is an extreme dwarf galaxy with one of the highest MHI/L ratios known.

  19. Data Report on Post-Irradiation Dimensional Change of AGC-1 Samples

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    William Windes

    This report summarizes the initial dimensional changes for loaded and unloaded AGC-1 samples. The dimensional change for all samples is presented as a function of dose. The data is further presented by graphite type and applied load levels to illustrate the differences between graphite forming processes and stress levels within the graphite components. While the three different loads placed on the samples have been verified [ ref: Larry Hull’s report] verification of the AGC-1 sample temperatures and dose levels are expected in the summer of 2012. Only estimated dose and temperature values for the samples are presented in this reportmore » to allow a partial analysis of the results.« less

  20. The Intriguing Case of the (Almost) Dark Galaxy AGC 229385

    NASA Astrophysics Data System (ADS)

    Salzer, John

    2015-10-01

    The ALFALFA blind HI survey has catalogued tens of thousands of HI sources over 7000 square degrees of high Galactic latitude sky. While the vast majority of the sources in ALFALFA have optical counterparts in existing wide-field surveys like SDSS, a class of objects has been identified that have no obvious optical counterparts in existing catalogs. Dubbed almost dark galaxies, these objects represent an extreme in the continuum of galaxy properties, with the highest HI mass-to-optical light ratios ever measured. We propose to use HST to observe AGC 229385, an almost dark object found in deep WIYN imaging to have an ultra-low surface brightness stellar component with extremely blue colors. AGC 229385 falls well off of all galaxy scaling relationships, including the Baryonic Tully-Fisher relation. Ground-based optical and HI data have been able to identify this object as extreme, but are insufficient to constrain the properties of its stellar component or its distance - for this, we need HST. Our science goals are twofold: to better constrain the distance to AGC 229385, and to investigate the stellar population(s) in this mysterious object. The requested observations will not only provide crucial insight into the properties and evolution of this specific system but will also help us understand this important class of ultra low surface brightness, gas-rich galaxies. The proposed observations are designed to be exploratory, yet they promise to pay rich dividends for a modest investment in observing time.

  1. A digitally controlled AGC loop circuitry for GNSS receiver chip with a binary weighted accurate dB-linear PGA

    NASA Astrophysics Data System (ADS)

    Gang, Jin; Yiqi, Zhuang; Yue, Yin; Miao, Cui

    2015-03-01

    A novel digitally controlled automatic gain control (AGC) loop circuitry for the global navigation satellite system (GNSS) receiver chip is presented. The entire AGC loop contains a programmable gain amplifier (PGA), an AGC circuit and an analog-to-digital converter (ADC), which is implemented in a 0.18 μm complementary metal-oxide-semiconductor (CMOS) process and measured. A binary-weighted approach is proposed in the PGA to achieve wide dB-linear gain control with small gain error. With binary-weighted cascaded amplifiers for coarse gain control, and parallel binary-weighted trans-conductance amplifier array for fine gain control, the PGA can provide a 64 dB dynamic range from -4 to 60 dB in 1.14 dB gain steps with a less than 0.15 dB gain error. Based on the Gaussian noise statistic characteristic of the GNSS signal, a digital AGC circuit is also proposed with low area and fast settling. The feed-backward AGC loop occupies an area of 0.27 mm2 and settles within less than 165 μs while consuming an average current of 1.92 mA at 1.8 V.

  2. Autoregulation of kinase dephosphorylation by ATP binding in AGC protein kinases.

    PubMed

    Chan, Tung O; Pascal, John M; Armen, Roger S; Rodeck, Ulrich

    2012-02-01

    AGC kinases, including the three Akt (protein kinase B) isoforms, protein kinase A (PKA) and all protein kinase C (PKC) isoforms, require activation loop phosphorylation (threonine 308 in Akt1) as well as phosphorylation of a C-terminal residue (serine 473 in Akt1) for catalytic activity and phosphorylation of downstream targets. Conversely, phosphatases reverse these phosphorylations. Virtually all cellular processes are affected by AGC kinases, a circumstance that has led to intense scrutiny of the molecular mechanisms that regulate phosphorylation of these kinases. Here, we review a new layer of control of phosphorylation in Akt, PKA and PKC pointing to ATP binding pocket occupancy as a means to decelerate dephosphorylation of these and, potentially, other kinases. This additional level of kinase regulation opens the door to search for new functional motifs for the rational design of non- ATP-competitive kinase inhibitors that discriminate within and between protein kinase families.

  3. FUEL-FLEXIBLE GASIFICATION-COMBUSTION TECHNOLOGY FOR PRODUCTION OF H2 AND SEQUESTRATION-READY CO2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    George Rizeq; Janice West; Arnaldo Frydman

    It is expected that in the 21st century the Nation will continue to rely on fossil fuels for electricity, transportation, and chemicals. It will be necessary to improve both the thermodynamic efficiency and environmental impact performance of fossil fuel utilization. General Electric Energy and Environmental Research Corporation (GE EER) has developed an innovative fuel-flexible Advanced Gasification-Combustion (AGC) concept to produce H{sub 2} and sequestration-ready CO{sub 2} from solid fuels. The AGC module offers potential for reduced cost and increased energy efficiency relative to conventional gasification and combustion systems. GE EER was awarded a Vision-21 program from U.S. DOE NETL tomore » develop the AGC technology. Work on this three-year program started on October 1, 2000. The project team includes GE EER, California Energy Commission, Southern Illinois University at Carbondale, and T. R. Miles, Technical Consultants, Inc. In the AGC technology, coal/opportunity fuels and air are simultaneously converted into separate streams of (1) pure hydrogen that can be utilized in fuel cells, (2) sequestration-ready CO{sub 2}, and (3) high temperature/pressure oxygen-depleted air to produce electricity in a gas turbine. The process produces near-zero emissions and, based on preliminary modeling work in the first quarter of this program, has an estimated process efficiency of approximately 67% based on electrical and H{sub 2} energy outputs relative to the higher heating value of coal. The three-year R&D program will determine the operating conditions that maximize separation of CO{sub 2} and pollutants from the vent gas, while simultaneously maximizing coal conversion efficiency and hydrogen production. The program integrates lab-, bench- and pilot-scale studies to demonstrate the AGC concept. This is the fifth quarterly technical progress report for the Vision-21 AGC program supported by U.S. DOE NETL (Contract: DE-FC26-00FT40974). This report summarizes

  4. FUEL-FLEXIBLE GASIFICATION-COMBUSTION TECHNOLOGY FOR PRODUCTION OF H2 AND SEQUESTRATION-READY CO2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    George Rizeq; Janice West; Arnaldo Frydman

    It is expected that in the 21st century the Nation will continue to rely on fossil fuels for electricity, transportation, and chemicals. It will be necessary to improve both the thermodynamic efficiency and environmental impact performance of fossil fuel utilization. General Electric Energy and Environmental Research Corporation (GE EER) has developed an innovative fuel-flexible Advanced Gasification-Combustion (AGC) concept to produce H{sub 2} and sequestration-ready CO{sub 2} from solid fuels. The AGC module offers potential for reduced cost and increased energy efficiency relative to conventional gasification and combustion systems. GE EER was awarded a Vision-21 program from U.S. DOE NETL tomore » develop the AGC technology. Work on this three-year program started on October 1, 2000. The project team includes GE EER, California Energy Commission, Southern Illinois University at Carbondale, and T. R. Miles, Technical Consultants, Inc. In the AGC technology, coal/opportunity fuels and air are simultaneously converted into separate streams of (1) pure hydrogen that can be utilized in fuel cells, (2) sequestration-ready CO{sub 2}, and (3) high temperature/pressure oxygen-depleted air to produce electricity in a gas turbine. The process produces near-zero emissions and, based on preliminary modeling work in the first quarter of this program, has an estimated process efficiency of approximately 67% based on electrical and H{sub 2} energy outputs relative to the higher heating value of coal. The three-year R&D program will determine the operating conditions that maximize separation of CO{sub 2} and pollutants from the vent gas, while simultaneously maximizing coal conversion efficiency and hydrogen production. The program integrates lab-, bench- and pilot-scale studies to demonstrate the AGC concept. This is the seventh quarterly technical progress report for the Vision-21 AGC program supported by U.S. DOE NETL (Contract: DE-FC26-00FT40974). This report summarizes

  5. FUEL-FLEXIBLE GASIFICATION-COMBUSTION TECHNOLOGY FOR PRODUCTION OF H2 AND SEQUESTRATION-READY CO2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    George Rizeq; Janice West; Arnaldo Frydman

    It is expected that in the 21st century the Nation will continue to rely on fossil fuels for electricity, transportation, and chemicals. It will be necessary to improve both the thermodynamic efficiency and environmental impact performance of fossil fuel utilization. GE Energy and Environmental Research Corporation (GE EER) has developed an innovative fuel-flexible Advanced Gasification-Combustion (AGC) concept to produce H{sub 2} and sequestration-ready CO{sub 2} from solid fuels. The AGC module offers potential for reduced cost and increased energy efficiency relative to conventional gasification and combustion systems. GE EER was awarded a Vision 21 program from U.S. DOE NETL tomore » develop the AGC technology. Work on this three-year program started on October 1, 2000. The project team includes GE EER, California Energy Commission, Southern Illinois University at Carbondale, and T. R. Miles, Technical Consultants, Inc. In the AGC technology, coal/opportunity fuels and air are simultaneously converted into separate streams of (1) pure hydrogen that can be utilized in fuel cells, (2) sequestration-ready CO{sub 2}, and (3) high temperature/pressure oxygen-depleted air to produce electricity in a gas turbine. The process produces near-zero emissions and, based on preliminary modeling work, has an estimated process efficiency of approximately 67% based on electrical and H{sub 2} energy outputs relative to the higher heating value of coal. The three-year R&D program will determine the operating conditions that maximize separation of CO{sub 2} and pollutants from the vent gas, while simultaneously maximizing coal conversion efficiency and hydrogen production. The program integrates lab-, bench- and pilot-scale studies to demonstrate the AGC concept. This is the second annual technical progress report for the Vision 21 AGC program supported by U.S. DOE NETL (Contract No. DE-FC26-00FT40974). This report summarizes program accomplishments for the period starting

  6. FUEL-FLEXIBLE GASIFICATION-COMBUSTION TECHNOLOGY FOR PRODUCTION OF H2 AND SEQUESTRATION-READY CO2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    George Rizeq; Janice West; Arnaldo Frydman

    It is expected that in the 21st century the Nation will continue to rely on fossil fuels for electricity, transportation, and chemicals. It will be necessary to improve both the thermodynamic efficiency and environmental impact performance of fossil fuel utilization. General Electric Energy and Environmental Research Corporation (GE EER) has developed an innovative fuel-flexible Advanced Gasification-Combustion (AGC) concept to produce H{sub 2} and sequestration-ready CO{sub 2} from solid fuels. The AGC module offers potential for reduced cost and increased energy efficiency relative to conventional gasification and combustion systems. GE EER was awarded a Vision-21 program from U.S. DOE NETL tomore » develop the AGC technology. Work on this three-year program started on October 1, 2000. The project team includes GE EER, California Energy Commission, Southern Illinois University at Carbondale, and T. R. Miles, Technical Consultants, Inc. In the AGC technology, coal/opportunity fuels and air are simultaneously converted into separate streams of (1) pure hydrogen that can be utilized in fuel cells, (2) sequestration-ready CO{sub 2}, and (3) high temperature/pressure oxygen-depleted air to produce electricity in a gas turbine. The process produces near-zero emissions and, based on preliminary modeling work in the first quarter of this program, has an estimated process efficiency of approximately 67% based on electrical and H{sub 2} energy outputs relative to the higher heating value of coal. The three-year R&D program will determine the operating conditions that maximize separation of CO{sub 2} and pollutants from the vent gas, while simultaneously maximizing coal conversion efficiency and hydrogen production. The program integrates lab-, bench- and pilot-scale studies to demonstrate the AGC concept. This is the third quarterly technical progress report for the Vision-21 AGC program supported by U.S. DOE NETL (Contract: DE-FC26-00FT40974). This report summarizes

  7. Design and performance test of a MEMS vibratory gyroscope with a novel AGC force rebalance control

    NASA Astrophysics Data System (ADS)

    Sung, Woon-Tahk; Sung, Sangkyung; Lee, Jang Gyu; Kang, Taesam

    2007-10-01

    In this paper, the development and performance test results of a laterally oscillating MEMS gyroscope using a novel force rebalance control strategy are presented. The micromachined structure and electrodes are fabricated using the deep reactive ion etching (DRIE) and anodic wafer bonding process. The high quality factor required for the resonance-based sensor is achieved using a vacuum-sealed device package. A systematic design approach of the force rebalance control is applied via a modified automatic gain control (AGC) method. The rebalance control design takes advantages of a novel AGC loop modification, which allows the approximation of the system's dynamics into a simple linear form. Using the proposed modification of AGC and the rebalance strategy that maintains a biased oscillation, a number of performance improvements including bandwidth extension and widened operating range were observed to be achieved. Finally, the experimental results of the gyroscope's practical application verify the feasibility and performance of the developed sensor.

  8. Autoregulation of kinase dephosphorylation by ATP binding to AGC protein kinases

    PubMed Central

    Pascal, John M; Armen, Roger S

    2012-01-01

    AGC kinases, including the three Akt (protein kinase B) isoforms, protein kinase A (PKA) and all protein kinase C (PKC) isoforms, require activation loop phosphorylation (threonine 308 in Akt1) as well as phosphorylation of a C-terminal residue (serine 473 in Akt1) for catalytic activity and phosphorylation of downstream targets. Conversely, phosphatases reverse these phosphorylations. Virtually all cellular processes are affected by AGC kinases, a circumstance that has led to intense scrutiny of the molecular mechanisms that regulate phosphorylation of these kinases. Here, we review a new layer of control of phosphorylation in Akt, PKA and PKC pointing to ATP binding pocket occupancy as a means to decelerate dephosphorylation of these and, potentially, other kinases. This additional level of kinase regulation opens the door to search for new functional motifs for the rational design of non-ATP-competitive kinase inhibitors that discriminate within and between protein kinase families. PMID:22262182

  9. Design and realization of an AEC&AGC system for the CCD aerial camera

    NASA Astrophysics Data System (ADS)

    Liu, Hai ying; Feng, Bing; Wang, Peng; Li, Yan; Wei, Hao yun

    2015-08-01

    An AEC and AGC(Automatic Exposure Control and Automatic Gain Control) system was designed for a CCD aerial camera with fixed aperture and electronic shutter. The normal AEC and AGE algorithm is not suitable to the aerial camera since the camera always takes high-resolution photographs in high-speed moving. The AEC and AGE system adjusts electronic shutter and camera gain automatically according to the target brightness and the moving speed of the aircraft. An automatic Gamma correction is used before the image is output so that the image is better for watching and analyzing by human eyes. The AEC and AGC system could avoid underexposure, overexposure, or image blurring caused by fast moving or environment vibration. A series of tests proved that the system meet the requirements of the camera system with its fast adjusting speed, high adaptability, high reliability in severe complex environment.

  10. The Extremely Metal-Poor Dwarf Galaxy AGC 198691

    NASA Astrophysics Data System (ADS)

    Hirschauer, Alec S.; Salzer, John Joseph; Cannon, John M.; Skillman, Evan D.; SHIELD II Team

    2016-01-01

    We present spectroscopic observations of the nearby dwarf irregular galaxy AGC 198691. This object is part of the Survey of HI in Extremely Low-Mass Dwarfs (SHIELD) sample, which consists of ultra-low HI mass galaxies discovered by the Arecibo Legacy Fast-Acting ALFA (ALFALFA) survey. SHIELD is a multi-configuration Expanded Very Large Array (EVLA) study of the neutral gas content and dynamics of galaxies with HI masses in the range of 106-107 M⊙. Our spectral data were obtained using the new high-throughput KPNO Ohio State Multi-Object Spectrograph (KOSMOS) on the Mayall 4-m telescope as part of a systematic study of the nebular abundances in the SHIELD galaxy sample. These observations enable measurement of the temperature sensitive [OIII]λ4363 line and hence the determination of a "direct" oxygen abundance for AGC 198691. We find this system to be an extremely metal-deficient (XMD) galaxy with an oxygen abundance comparable to such objects as I Zw 18, SBS 0335-052W, Leo P, and DDO 68 - the lowest metallicity star-forming systems known. It is worth noting that two of the five lowest-abundance galaxies currently recognized were discovered via the ALFALFA blind HI survey. These XMD galaxies are potential analogues to the first star-forming systems, which through hierarchical accretion processes built up the large galaxies we observe today in the local Universe. Detailed analysis of such XMD systems offers observational constraint to models of galactic evolution and star formation histories to allow a better understanding of the processes that govern the chemical evolution of low-mass galaxies.

  11. Detection of an Optical Counterpart to the ALFALFA Ultra-compact High-velocity Cloud AGC 249525

    NASA Astrophysics Data System (ADS)

    Janesh, William; Rhode, Katherine L.; Salzer, John J.; Janowiecki, Steven; Adams, Elizabeth A. K.; Haynes, Martha P.; Giovanelli, Riccardo; Cannon, John M.

    2017-03-01

    We report on the detection at >98% confidence of an optical counterpart to AGC 249525, an ultra-compact high-velocity cloud (UCHVC) discovered by the Arecibo Legacy Fast ALFA survey blind neutral hydrogen survey. UCHVCs are compact, isolated H I clouds with properties consistent with their being nearby low-mass galaxies, but without identified counterparts in extant optical surveys. Analysis of the resolved stellar sources in deep g- and I-band imaging from the WIYN pODI camera reveals a clustering of possible red giant branch stars associated with AGC 249525 at a distance of 1.64 ± 0.45 Mpc. Matching our optical detection with the H I synthesis map of AGC 249525 from Adams et al. shows that the stellar overdensity is exactly coincident with the highest-density H I contour from that study. Combining our optical photometry and the H I properties of this object yields an absolute magnitude of -7.1≤slant {M}V≤slant -4.5, a stellar mass between 2.2+/- 0.6× {10}4 {M}⊙ and 3.6+/- 1.0× {10}5 {M}⊙ , and an H I to stellar mass ratio between 9 and 144. This object has stellar properties within the observed range of gas-poor ultra-faint dwarfs in the Local Group, but is gas-dominated.

  12. AT13148, a first-in-class multi-AGC kinase inhibitor, potently inhibits gastric cancer cells both in vitro and in vivo

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xi, Yu; Department of General Surgery, First Affiliated Hospital, School of Medicine, Shihezi University, Shihezi, Xinjiang 832008; Niu, Jianhua

    The AGC kinase family is important cell proliferation and survival. Dysregulation of this family contributes to gastric cancer progression. Here, we evaluated the potential activity of AT13148, a first-in-class multi-AGC kinase inhibitor, against gastric cancer cells. Our results showed that AT13148 exerted potent cytotoxic and anti-proliferative activities against a panel human gastric cancer cell lines (HGC-27, AGS, SNU-601, N87 and MKN-28), possibly via inducing cancer cell apoptotic death. Apoptosis inhibition by the Caspase blockers dramatically attenuated AT13148-caused cytotoxicity against gastric cancer cells. Intriguingly, same AT13148 treatment was not cytotoxic/pro-apoptotic to the non-cancerous human gastric epithelial GEC-1 cells. At the signaling level,more » AT13148 treatment in gastric cancer cells dramatically suppressed activation of multiple AGC kinases, including Akt (at p-Thr-308), p70S6 kinase (p70S6K), glycogen synthase kinase 3β (GSK-3β) and p90 ribosomal S6 kinase (RSK). Our in vivo studies demonstrated that daily oral gavage of AT13148 at well-tolerated doses significantly inhibited HGC27 xenograft tumor growth in nude mice. AGC activity was also dramatically decreased in AT13148-administrated HGC27 tumors. Therefore, targeting AGC kinases by AT13148 demonstrates superior anti-gastric cancer activity both in vitro and in vivo. The preclinical results of this study support the progression of this molecule into future evaluation as a valuable anti-gastric cancer candidate. - Highlights: • AT13148 is cytotoxic and anti-proliferative to human gastric cancer cells. • AT13148 induces gastric cancer cell apoptotic death, inhibited by Caspase inhibitors. • AT13148 inactivates multiple AGC kinases in human gastric cancer cells. • AT13148 oral administration suppresses HGC27 xenograft growth in nude mice. • AT13148 oral administration inhibits multiple AGC kinases in HGC27 xenograft tumors.« less

  13. Fuel-Flexible Gasification-Combustion Technology for Production of Hydrogen and Sequestration-Ready Carbon Dioxide

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rizeq, George; West, Janice; Frydman, Arnaldo

    Electricity produced from hydrogen in fuel cells can be highly efficient relative to competing technologies and has the potential to be virtually pollution free. Thus, fuel cells may become an ideal solution to this nation's energy needs if one has a satisfactory process for producing hydrogen from available energy resources such as coal, and low-cost alternative feedstocks such as biomass. GE EER is developing an innovative fuel-flexible advanced gasification-combustion (AGC) technology for production of hydrogen for fuel cells or combustion turbines, and a separate stream of sequestration-ready CO2. The AGC module can be integrated into a number of Vision- 21more » power systems. It offers increased energy efficiency relative to conventional gasification and combustion systems and near-zero pollution. The R&D on the AGC technology is being conducted under a Vision-21 award from the U.S. DOE NETL with co-funding from GE EER, Southern Illinois University at Carbondale (SIU-C), and the California Energy Commission (CEC). The AGC technology converts coal and air into three separate streams of pure hydrogen, sequestration-ready CO2, and high temperature/pressure oxygen-depleted air to produce electricity in a gas turbine. The three-year program integrates lab-, bench- and pilot-scale studies to demonstrate the AGC concept. Process and kinetic modeling studies as well as an economic assessment will also be performed. This paper provides an overview of the program and its objectives, and discusses first-year R&D activities, including design of experimental facilities and results from initial tests and modeling studies. In particular, the paper describes the design of the bench-scale facility and initial process modeling data. In addition, a process flow diagram is shown for a complete plant incorporating the AGC module with other Vision-21 plant components to maximize hydrogen production and process efficiency.« less

  14. Hydrostatic calculations of axisymmetric flow and its stability for the AGCE model

    NASA Technical Reports Server (NTRS)

    Miller, T. L.; Gall, R. L.

    1981-01-01

    Baroclinic waves in the atmospherics general circulation experiment (AGCE) apparatus by the use of numerical hydrostatic primitive equation models were determined. The calculation is accomplished by using an axisymmetric primitive equation model to compute, for a given set of experimental parameters, a steady state axisymmetric flow and then testing this axisymmetric flow for stability using a linear primitive equation model. Some axisymmetric flows are presented together with preliminary stability calculations.

  15. Enhancement of anti-stokes sensitized luminescence in AgCl(I) crystals in the presence of silver nanoparticles

    NASA Astrophysics Data System (ADS)

    Chung, Nguyen Thi Kim; Egorushina, E. A.; Latyshev, A. N.; Ovchinnikov, O. V.; Smirnov, M. S.; Suvorova, T. I.

    2012-01-01

    We have observed a significant increase in the intensity with anti-Stokes excitation of recombination luminescence in AgCl(I) microcrystals sensitized by methylene blue molecules in the presence of silver nanoparticles.

  16. Testbed-based Performance Evaluation of Attack Resilient Control for AGC

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ashok, Aditya; Sridhar, Siddharth; McKinnon, Archibald D.

    The modern electric power grid is a complex cyber-physical system whose reliable operation is enabled by a wide-area monitoring and control infrastructure. This infrastructure, supported by an extensive communication backbone, enables several control applications functioning at multiple time scales to ensure the grid is maintained within stable operating limits. Recent events have shown that vulnerabilities in this infrastructure may be exploited to manipulate the data being exchanged. Such a scenario could cause the associated control application to mis-operate, potentially causing system-wide instabilities. There is a growing emphasis on looking beyond traditional cybersecurity solutions to mitigate such threats. In this papermore » we perform a testbed-based validation of one such solution - Attack Resilient Control (ARC) - on Iowa State University's \\textit{PowerCyber} testbed. ARC is a cyber-physical security solution that combines domain-specific anomaly detection and model-based mitigation to detect stealthy attacks on Automatic Generation Control (AGC). In this paper, we first describe the implementation architecture of the experiment on the testbed. Next, we demonstrate the capability of stealthy attack templates to cause forced under-frequency load shedding in a 3-area test system. We then validate the performance of ARC by measuring its ability to detect and mitigate these attacks. Our results reveal that ARC is efficient in detecting stealthy attacks and enables AGC to maintain system operating frequency close to its nominal value during an attack. Our studies also highlight the importance of testbed-based experimentation for evaluating the performance of cyber-physical security and control applications.« less

  17. Comparison between the Strength Levels of Baseline Nuclear-Grade Graphite and Graphite Irradiated in AGC-2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carroll, Mark Christopher

    2015-07-01

    This report details the initial comparison of mechanical strength properties between the cylindrical nuclear-grade graphite specimens irradiated in the second Advanced Graphite Creep (AGC-2) experiment with the established baseline, or unirradiated, mechanical properties compiled in the Baseline Graphite Characterization program. The overall comparative analysis will describe the development of an appropriate test protocol for irradiated specimens, the execution of the mechanical tests on the AGC-2 sample population, and will further discuss the data in terms of developing an accurate irradiated property distribution in the limited amount of irradiated data by leveraging the considerably larger property datasets being captured in themore » Baseline Graphite Characterization program. Integrating information on the inherent variability in nuclear-grade graphite with more complete datasets is one of the goals of the VHTR Graphite Materials program. Between “sister” specimens, or specimens with the same geometry machined from the same sub-block of graphite from which the irradiated AGC specimens were extracted, and the Baseline datasets, a comprehensive body of data will exist that can provide both a direct and indirect indication of the full irradiated property distributions that can be expected of irradiated nuclear-grade graphite while in service in a VHTR system. While the most critical data will remain the actual irradiated property measurements, expansion of this data into accurate distributions based on the inherent variability in graphite properties will be a crucial step in qualifying graphite for nuclear use as a structural material in a VHTR environment.« less

  18. Controlling Wind Turbines for Secondary Frequency Regulation: An Analysis of AGC Capabilities Under New Performance Based Compensation Policy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aho, Jacob; Pao, Lucy Y.; Fleming, Paul

    2014-11-13

    As wind energy becomes a larger portion of the world's energy portfolio there has been an increased interest for wind turbines to control their active power output to provide ancillary services which support grid reliability. One of these ancillary services is the provision of frequency regulation, also referred to as secondary frequency control or automatic generation control (AGC), which is often procured through markets which recently adopted performance-based compensation. A wind turbine with a control system developed to provide active power ancillary services can be used to provide frequency regulation services. Simulations have been performed to determine the AGC trackingmore » performance at various power schedule set-points, participation levels, and wind conditions. The performance metrics used in this study are based on those used by several system operators in the US. Another metric that is analyzed is the damage equivalent loads (DELs) on turbine structural components, though the impacts on the turbine electrical components are not considered. The results of these single-turbine simulations show that high performance scores can be achieved when there are insufficient wind resources available. The capability of a wind turbine to rapidly and accurately follow power commands allows for high performance even when tracking rapidly changing AGC signals. As the turbine de-rates to meet decreased power schedule set-points there is a reduction in the DELs, and the participation in frequency regulation has a negligible impact on these loads.« less

  19. Flexible Ag-C60 nano-biosensors based on surface plasmon coupled emission for clinical and forensic applications.

    PubMed

    Mulpur, Pradyumna; Yadavilli, Sairam; Mulpur, Praharsha; Kondiparthi, Neeharika; Sengupta, Bishwambhar; Rao, Apparao M; Podila, Ramakrishna; Kamisetti, Venkataramaniah

    2015-10-14

    The relatively low sensitivity of fluorescence detection schemes, which are mainly limited by the isotropic nature of fluorophore emission, can be overcome by utilizing surface plasmon coupled emission (SPCE). In this study, we demonstrate directional emission from fluorophores on flexible Ag-C60 SPCE sensor platforms for point-of-care sensing, in healthcare and forensic sensing scenarios, with at least 10 times higher sensitivity than traditional fluorescence sensing schemes. Adopting the highly sensitive Ag-C60 SPCE platform based on glass and novel low-cost flexible substrates, we report the unambiguous detection of acid-fast Mycobacterium tuberculosis (Mtb) bacteria at densities as low as 20 Mtb mm(-2); from non-acid-fast bacteria (e.g., E. coli and S. aureus), and the specific on-site detection of acid-fast sperm cells in human semen samples. In combination with the directional emission and high-sensitivity of SPCE platforms, we also demonstrate the utility of smartphones that can replace expensive and cumbersome detectors to enable rapid hand-held detection of analytes in resource-limited settings; a much needed critical advance to biosensors, for developing countries.

  20. AGC-2 Irradiation Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rohrbaugh, David Thomas; Windes, William; Swank, W. David

    components longer useful lifetimes within the core. Determining the irradiation creep rates of nuclear grade graphites is critical for determining the useful lifetime of graphite components and is a major component of the Advanced Graphite Creep (AGC) experiment.« less

  1. Role of AGC1/aralar in the metabolic synergies between neuron and glia.

    PubMed

    Contreras, Laura

    2015-09-01

    Brain energetic requirements are elevated due to the high cost of impulse transmission and information storage, and are met mainly by glucose oxidation. The energy needs are closely matched by metabolic regulation, which requires the close cooperation of neurons and astrocytes and involves highly regulated fluxes of metabolites between cells. The metabolism in each type of cell is determined in part by its proteomic profile, which has been regarded as complementary. This review will consider the cellular distribution of the mitochondrial aspartate-glutamate carrier, aralar/AGC1/SLC25A12, and its role in the synergic metabolism between neurons and astrocytes. Copyright © 2015 Elsevier Ltd. All rights reserved.

  2. Double-differential recording and AGC using microcontrolled variable gain ASIC.

    PubMed

    Rieger, Robert; Deng, Shin-Liang

    2013-01-01

    Low-power wearable recording of biopotentials requires acquisition front-ends with high common-mode rejection for interference suppression and adjustable gain to provide an optimum signal range to a cascading analogue-to-digital stage. A microcontroller operated double-differential (DD) recording setup and automatic gain control circuit (AGC) are discussed which reject common-mode interference and provide tunable gain, thus compensating for imbalance and variation in electrode interface impedance. Custom-designed variable gain amplifiers (ASIC) are used as part of the recording setup. The circuit gain and balance is set by the timing of microcontroller generated clock signals. Measured results are presented which confirm that improved common-mode rejection is achieved compared to a single differential amplifier in the presence of input network imbalance. Practical measured examples further validate gain control suitable for biopotential recording and power-line rejection for wearable ECG and EMG recording. The prototype front-end consumes 318 μW including amplifiers and microcontroller.

  3. The power grid AGC frequency bias coefficient online identification method based on wide area information

    NASA Astrophysics Data System (ADS)

    Wang, Zian; Li, Shiguang; Yu, Ting

    2015-12-01

    This paper propose online identification method of regional frequency deviation coefficient based on the analysis of interconnected grid AGC adjustment response mechanism of regional frequency deviation coefficient and the generator online real-time operation state by measured data through PMU, analyze the optimization method of regional frequency deviation coefficient in case of the actual operation state of the power system and achieve a more accurate and efficient automatic generation control in power system. Verify the validity of the online identification method of regional frequency deviation coefficient by establishing the long-term frequency control simulation model of two-regional interconnected power system.

  4. Regulation of planar growth by the Arabidopsis AGC protein kinase UNICORN.

    PubMed

    Enugutti, Balaji; Kirchhelle, Charlotte; Oelschner, Maxi; Torres Ruiz, Ramón Angel; Schliebner, Ivo; Leister, Dario; Schneitz, Kay

    2012-09-11

    The spatial coordination of growth is of central importance for the regulation of plant tissue architecture. Individual layers, such as the epidermis, are clonally propagated and structurally maintained by symmetric cell divisions that are oriented along the plane of the layer. The developmental control of this process is poorly understood. The simple cellular basis and sheet-like structure of Arabidopsis integuments make them an attractive model system to address planar growth. Here we report on the characterization of the Arabidopsis UNICORN (UCN) gene. Analysis of ucn integuments reveals localized distortion of planar growth, eventually resulting in an ectopic multicellular protrusion. In addition, ucn mutants exhibit ectopic growth in filaments and petals, as well as aberrant embryogenesis. We further show that UCN encodes an active AGC VIII kinase. Genetic, biochemical, and cell biological data suggest that UCN suppresses ectopic growth in integuments by directly repressing the KANADI transcription factor ABERRANT TESTA SHAPE. Our findings indicate that UCN represents a unique plant growth regulator that maintains planar growth of integuments by repressing a developmental regulator involved in the control of early integument growth and polarity.

  5. Hybrid Stochastic Search Technique based Suboptimal AGC Regulator Design for Power System using Constrained Feedback Control Strategy

    NASA Astrophysics Data System (ADS)

    Ibraheem, Omveer, Hasan, N.

    2010-10-01

    A new hybrid stochastic search technique is proposed to design of suboptimal AGC regulator for a two area interconnected non reheat thermal power system incorporating DC link in parallel with AC tie-line. In this technique, we are proposing the hybrid form of Genetic Algorithm (GA) and simulated annealing (SA) based regulator. GASA has been successfully applied to constrained feedback control problems where other PI based techniques have often failed. The main idea in this scheme is to seek a feasible PI based suboptimal solution at each sampling time. The feasible solution decreases the cost function rather than minimizing the cost function.

  6. Combined effect of pulse density and grid cell size on predicting and mapping aboveground carbon in fast-growing Eucalyptus forest plantation using airborne LiDAR data.

    PubMed

    Silva, Carlos Alberto; Hudak, Andrew Thomas; Klauberg, Carine; Vierling, Lee Alexandre; Gonzalez-Benecke, Carlos; de Padua Chaves Carvalho, Samuel; Rodriguez, Luiz Carlos Estraviz; Cardil, Adrián

    2017-12-01

    LiDAR remote sensing is a rapidly evolving technology for quantifying a variety of forest attributes, including aboveground carbon (AGC). Pulse density influences the acquisition cost of LiDAR, and grid cell size influences AGC prediction using plot-based methods; however, little work has evaluated the effects of LiDAR pulse density and cell size for predicting and mapping AGC in fast-growing Eucalyptus forest plantations. The aim of this study was to evaluate the effect of LiDAR pulse density and grid cell size on AGC prediction accuracy at plot and stand-levels using airborne LiDAR and field data. We used the Random Forest (RF) machine learning algorithm to model AGC using LiDAR-derived metrics from LiDAR collections of 5 and 10 pulses m -2 (RF5 and RF10) and grid cell sizes of 5, 10, 15 and 20 m. The results show that LiDAR pulse density of 5 pulses m -2 provides metrics with similar prediction accuracy for AGC as when using a dataset with 10 pulses m -2 in these fast-growing plantations. Relative root mean square errors (RMSEs) for the RF5 and RF10 were 6.14 and 6.01%, respectively. Equivalence tests showed that the predicted AGC from the training and validation models were equivalent to the observed AGC measurements. The grid cell sizes for mapping ranging from 5 to 20 also did not significantly affect the prediction accuracy of AGC at stand level in this system. LiDAR measurements can be used to predict and map AGC across variable-age Eucalyptus plantations with adequate levels of precision and accuracy using 5 pulses m -2 and a grid cell size of 5 m. The promising results for AGC modeling in this study will allow for greater confidence in comparing AGC estimates with varying LiDAR sampling densities for Eucalyptus plantations and assist in decision making towards more cost effective and efficient forest inventory.

  7. ARALAR/AGC1 deficiency, a neurodevelopmental disorder with severe impairment of neuronal mitochondrial respiration, does not produce a primary increase in brain lactate.

    PubMed

    Juaristi, Inés; García-Martín, María L; Rodrigues, Tiago B; Satrústegui, Jorgina; Llorente-Folch, Irene; Pardo, Beatriz

    2017-07-01

    ARALAR/AGC1 (aspartate-glutamate mitochondrial carrier 1) is an important component of the NADH malate-aspartate shuttle (MAS). AGC1-deficiency is a rare disease causing global cerebral hypomyelination, developmental arrest, hypotonia, and epilepsy (OMIM ID #612949); the aralar-KO mouse recapitulates the major findings in humans. This study was aimed at understanding the impact of ARALAR-deficiency in brain lactate levels as a biomarker. We report that lactate was equally abundant in wild-type and aralar-KO mouse brain in vivo at postnatal day 17. We find that lactate production upon mitochondrial blockade depends on up-regulation of lactate formation in astrocytes rather than in neurons. However, ARALAR-deficiency decreased cell respiration in neurons, not astrocytes, which maintained unchanged respiration and lactate production. As the primary site of ARALAR-deficiency is neuronal, this explains the lack of accumulation of brain lactate in ARALAR-deficiency in humans and mice. On the other hand, we find that the cytosolic and mitochondrial components of the glycerol phosphate shuttle are present in astrocytes with similar activities. This suggests that glycerol phosphate shuttle is the main NADH shuttle in astrocytes and explains the absence of effects of ARALAR-deficiency in these cells. © 2017 International Society for Neurochemistry.

  8. Direct electrochemistry and electrocatalytic behavior of hemoglobin entrapped in Ag@C nanocables/gold nanoparticles nanocomposites film.

    PubMed

    Hu, Xiao-Wei; Mao, Chang-Jie; Song, Ji-Ming; Niu, He-Lin; Zhang, Sheng-Yi; Cui, Rong-Jing

    2012-10-01

    Direct electrochemistry of hemoglobin (Hb) was successfully fabricated by immobilizing Hb on the nanocomposites containing of Ag@C nanocables and Au nanoparticles (AuNPs) modified glassy carbon electrode (GCE). The immobilized Hb retained its biological activity and shown high catalytic activities to the reduction of H2O2 by circular dicroism (CD) spectrum, fourier transform infrared (FT-IR) spectrum and cyclic voltammetry (CV). Experimental conditions such as scan rate and pH Value were studied and optimized. The results indicated that the resulting biosensor are linear to the concentrations of H2O2 in the ranges of 6.67 x 10(-7)-2.40 x 10(5) M, and the detection limit is 2.02 x 10(-7) M. The electrochemical biosensor has also high stability and good reproducibility.

  9. Applying Technology in the Work Environment.

    ERIC Educational Resources Information Center

    Greenwood, Reed, Ed.

    A series of papers is presented from two symposia sponsored by the Work Environment and Technology Committee and offered at annual conferences of the President's Committee on Employment of People with Disabilities. The 1988 symposium was called "Applying Technology in the Work Environment" and the 1989 symposium was called "Reasonable…

  10. Work with Us | Geothermal Technologies | NREL

    Science.gov Websites

    work with us and leverage our geothermal research, facilities, and expertise. Contact Us Photo of develop, test, and evaluate geothermal technologies. Commercialize Your Technology Accelerate the transfer

  11. Managing Technology Resourcefully: Part II--Working with Your District's Technology

    ERIC Educational Resources Information Center

    Weeks, Richard

    2009-01-01

    A large school district may have a technology department staffed by a chief technology officer who supervises two or more directors of operations, project managers, and technicians. On the other hand, a small district may employ an information technologist who works with technicians, consultants, volunteers with a knack for technology, and…

  12. Assess and Predict Automatic Generation Control Performances for Thermal Power Generation Units Based on Modeling Techniques

    NASA Astrophysics Data System (ADS)

    Zhao, Yan; Yang, Zijiang; Gao, Song; Liu, Jinbiao

    2018-02-01

    Automatic generation control(AGC) is a key technology to maintain real time power generation and load balance, and to ensure the quality of power supply. Power grids require each power generation unit to have a satisfactory AGC performance, being specified in two detailed rules. The two rules provide a set of indices to measure the AGC performance of power generation unit. However, the commonly-used method to calculate these indices is based on particular data samples from AGC responses and will lead to incorrect results in practice. This paper proposes a new method to estimate the AGC performance indices via system identification techniques. In addition, a nonlinear regression model between performance indices and load command is built in order to predict the AGC performance indices. The effectiveness of the proposed method is validated through industrial case studies.

  13. Idea Technology and Product Technology: Seeing beyond the Text to the Technology That Works

    ERIC Educational Resources Information Center

    Bednar, Maryanne R.

    2004-01-01

    Sifting through the myriad "idea" technologies (such as multiple intelligence theories or Piaget's Theory of Cognitive Development) and "product" technologies (such as PowerPoint or digital cameras) can be overwhelming, but Bednar persuades us that it's not about having the most recent technology, it's about using what works for "your" students in…

  14. Technology in Social Work Education: A Systematic Review

    ERIC Educational Resources Information Center

    Wretman, Christopher J.; Macy, Rebecca J.

    2016-01-01

    Given the growing prevalence of technology-based instruction, social work faculty need a clear understanding of the strengths and limitations of these methods. We systematically examined the evidence for technology-based instruction in social work education. Using comprehensive and rigorous methods, 38 articles were included in the review. Of…

  15. Advanced Guidance and Control for Hypersonics and Space Access

    NASA Technical Reports Server (NTRS)

    Hanson, John M.; Hall, Charles E.; Mulqueen, John A.; Jones, Robert E.

    2003-01-01

    Advanced guidance and control (AG&C) technologies are critical for meeting safety, reliability, and cost requirements for the next generation of reusable launch vehicle (RLV), whether it is fully rocket-powered or has air- breathing components. This becomes clear upon examining the number of expendable launch vehicle failures in the recent past where AG&C technologies could have saved a RLV with the same failure mode, the additional vehicle problems where t h i s technology applies, and the costs and time associated with mission design with or without all these failure issues. The state-of-the-art in guidance and control technology, as well as in computing technology, is the point where we can look to the possibility of being able to safely return a RLV in any situation where it can physically be recovered. This paper outlines reasons for AWC, current technology efforts, and the additional work needed for making this goal a reality. There are a number of approaches to AG&C that have the potential for achieving the desired goals. For some of these methods, we compare the results of tests designed to demonstrate the achievement of the goals. Tests up to now have been focused on rocket-powered vehicles; application to hypersonic air-breathers is planned. We list the test cases used to demonstrate that the desired results are achieved, briefly describe an automated test scoring method, and display results of the tests. Some of the technology components have reached the maturity level where they are ready for application to a new vehicle concept, while others are not far along in development.

  16. Mechanisation and automation technologies development in work at construction sites

    NASA Astrophysics Data System (ADS)

    Sobotka, A.; Pacewicz, K.

    2017-10-01

    Implementing construction work that creates buildings is a very complicated and laborious task and requires the use of various types of machines and equipment. For years there has been a desire for designers and technologists to introduce devices that replace people’s work on machine construction, automation and even robots. Technologies for building construction are still being developed and implemented to limit people’s hard work and improve work efficiency and quality in innovative architectonical and construction solutions. New opportunities for improving work on the construction site include computerisation of technological processes and construction management for projects and processes. The aim of the paper was to analyse the development of mechanisation, automation and computerisation of construction processes and selected building technologies, with special attention paid to 3D printing technology. The state of mechanisation of construction works in Poland and trends in its development in construction technologies are presented. These studies were conducted on the basis of the available literature and a survey of Polish construction companies.

  17. Information flow and work productivity through integrated information technology

    NASA Technical Reports Server (NTRS)

    Wigand, R. T.

    1985-01-01

    The work environment surrounding integrated office systems is reviewed. The known effects of automated office technologies is synthesized and their known impact on work efficiency is reviewed. These effects are explored with regard to their impact on networks, work flow/processes, as well as organizational structure and power. Particular emphasis is given to structural changes due to the introduction of newer information technologies in organizations. The new information technologies have restructed the average organization's middle banks and, as a consequence, they have shrunk drastically. Organizational pyramids have flattened with fewer levels since executives have realized that they can get ahold of the needed information via the new technologies quicker and directly and do not have to rely on middle-level managers. Power shifts are typically accompanied with the introduction of these technologies resulting in the generation of a new form of organizational power.

  18. Group Work in a Technology-Rich Environment

    ERIC Educational Resources Information Center

    Penner, Nikolai; Schulze, Mathias

    2010-01-01

    This paper addresses several components of successful language-learning methodologies--group work, task-based instruction, and wireless computer technologies--and examines how the interplay of these three was perceived by students in a second-year university foreign-language course. The technology component of our learning design plays a central…

  19. Technology and Work. Research Review No. 2.

    ERIC Educational Resources Information Center

    Taviss, Irene; Gerber, William

    Recent literature reflecting the impact of technological change on the occupational distribution of the labor force and on work patterns and skills is reviewed. Social and policy implications of technological change which are considered include mechanisms for improving the coordination between labor supply and demand and the problems and prospects…

  20. Communication Technology: Pros and Cons of Constant Connection to Work

    ERIC Educational Resources Information Center

    Diaz, Ismael; Chiaburu, Dan S.; Zimmerman, Ryan D.; Boswell, Wendy R.

    2012-01-01

    We examined the relationship between employees' attitudes related to communication technology (CT) flexibility, communication technology (CT) use, work-to-life conflict and work satisfaction. Based on data obtained from 193 employees, CT flexibility predicted more CT use. Further, CT use was associated not only with increased work satisfaction,…

  1. Pilot Project Technology Business Case: Mobile Work Packages

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thomas, Ken; Lawrie, Sean; Niedermuller, Josef

    Performance advantages of the new pilot project technologies are widely acknowledged, but it has proven difficult for utilities to derive business cases for justifying investment in these new capabilities. Lack of a business case is often cited by utilities as a barrier to pursuing wide-scale application of digital technologies to nuclear plant work activities. The decision to move forward with funding usually hinges on demonstrating actual cost reductions that can be credited to budgets and thereby truly reduce O&M or capital costs. Technology enhancements, while enhancing work methods and making work more efficient, often fail to eliminate workload such thatmore » it changes overall staffing and material cost requirements. It is critical to demonstrate cost reductions or impacts on non-cost performance objectives in order for the business case to justify investment by nuclear operators. The Business Case Methodology (BCM) was developed in September of 2015 to frame the benefit side of II&C technologies to address the “benefit” side of the analysis—as opposed to the cost side—and how the organization evaluates discretionary projects (net present value (NPV), accounting effects of taxes, discount rates, etc.). The cost and analysis side is not particularly difficult for the organization and can usually be determined with a fair amount of precision (not withstanding implementation project cost overruns). It is in determining the “benefits” side of the analysis that utilities have more difficulty in technology projects and that is the focus of this methodology. The methodology is presented in the context of the entire process, but the tool provided is limited to determining the organizational benefits only. This report describes a the use of the BCM in building a business case for mobile work packages, which includes computer-based procedures and other automated elements of a work package. Key to those impacts will be identifying where the savings are

  2. Three-dimensional computer model for the atmospheric general circulation experiment

    NASA Technical Reports Server (NTRS)

    Roberts, G. O.

    1984-01-01

    An efficient, flexible, three-dimensional, hydrodynamic, computer code has been developed for a spherical cap geometry. The code will be used to simulate NASA's Atmospheric General Circulation Experiment (AGCE). The AGCE is a spherical, baroclinic experiment which will model the large-scale dynamics of our atmosphere; it has been proposed to NASA for future Spacelab flights. In the AGCE a radial dielectric body force will simulate gravity, with hot fluid tending to move outwards. In order that this force be dominant, the AGCE must be operated in a low gravity environment such as Spacelab. The full potential of the AGCE will only be realized by working in conjunction with an accurate computer model. Proposed experimental parameter settings will be checked first using model runs. Then actual experimental results will be compared with the model predictions. This interaction between experiment and theory will be very valuable in determining the nature of the AGCE flows and hence their relationship to analytical theories and actual atmospheric dynamics.

  3. 75 FR 21602 - Online Safety and Technology Working Group Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-26

    ... OSTWG is tasked with evaluating industry efforts to promote a safe online environment for children. The... and Technology Working Group Meeting AGENCY: National Telecommunications and Information... public meeting of the Online Safety and Technology Working Group (OSTWG). DATES: The meeting will be held...

  4. 75 FR 1338 - Online Safety and Technology Working Group Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-11

    ... promote a safe online environment for children. The Act requires the OSTWG to report its findings and... and Technology Working Group Meeting AGENCY: National Telecommunications and Information... public meeting of the Online Safety and Technology Working Group (OSTWG). DATES: The meeting will be held...

  5. Live Site Demonstration Munitions Response Program Site UXO 01 at Marine Corps Air Ground Combat Center (MCAGCC) Twentynine Palms, California

    DTIC Science & Technology

    2015-11-01

    ground surface (bgs) and is composed of crystalline igneous and metamorphic rocks . The ranges are located on Cajon soils (Jacobs Engineering Group...Twentynine Palms, California ESTCP Project MR-201229 NOVEMBER 2015 Steve Stacy ARCADIS- US , Inc. Distribution Statement A REPORT DOCUMENTATION PAGE...geophysical classification (AGC) technologies for Munitions Response (MR). This demonstration was designed to evaluate the use of AGC methodology

  6. Work zone intrusion alert technologies : assessment and practical guidance : final report.

    DOT National Transportation Integrated Search

    2017-06-01

    A work zone intrusion alert technology is a type of safety system that is used in a roadway work zone to alert field workers and secure time for them to escape when errant vehicles intrude into the work zone. Although such technologies have potential...

  7. Final Report of the Advanced Coal Technology Work Group

    EPA Pesticide Factsheets

    The Advanced Coal Technology workgroup reported to the Clean Air Act Advisory Committee. This page includes the final report of the Advanced Coal Technology Work Group to the Clean Air Act Advisory Committee.

  8. E-Technology and Work/Life Balance for Academics with Young Children

    ERIC Educational Resources Information Center

    Currie, Jan; Eveline, Joan

    2011-01-01

    Since the late 1980s, research on post-industrialized economies shows that the boundary between work and family is increasingly becoming blurred. The continuing evolution of e-technology allows work for some to be done anywhere, anytime. This article examines the degree to which e-technology has transferred work into the home lives of academics…

  9. Information and Communication Technologies in Social Work

    PubMed Central

    Perron, Brian E.; Taylor, Harry O.; Glass, Joseph E.; Margerum-Leys, Jon

    2011-01-01

    Information and communication technologies (ICTs) are electronic tools used to convey, manipulate and store information. The exponential growth of Internet access and ICTs greatly influenced social, political, and economic processes in the United States, and worldwide. Regardless of the level of practice, ICTs will continue influencing the careers of social workers and the clients they serve. ICTs have received some attention in the social work literature and curriculum, but we argue that this level of attention is not adequate given their ubiquity, growth and influence, specifically as it relates to upholding social work ethics. Significant attention is needed to help ensure social workers are responsive to the technological changes in the health care system, including the health care infrastructure and use of technology among clients. Social workers also need ICT competencies in order to effectively lead different types of social change initiatives or collaborate with professionals of other disciplines who are using ICTs as part of existing strategies. This paper also identifies potential pitfalls and challenges with respect to the adoption of ICTs, with recommendations for advancing their use in practice, education, and research. PMID:21691444

  10. Work and technological innovation in organic agriculture.

    PubMed

    Tereso, M J A; Abrahão, R F; Gemma, S F B; Montedo, U B; Menegon, N L; Guarneti, J E; Ribeiro, I A V

    2012-01-01

    Organic agriculture is a sustainable cultivation ecologically, economically and socially. Several researches in organic agriculture have been made from technical perspectives, economic traits or related to ecological aspects. There are practically no investigations into the nature of the technology used in organic agriculture, especially from an ergonomic perspective. From the activity analysis, this study aimed to map the technology used in the production of organic vegetables. Properties producing organic vegetables were selected representing the State of São Paulo. It was applied an instrument (questionnaire and semi-structured interview) with their managers and it was made visual records to identify adaptations, innovations and technological demands that simultaneously minimize the workload and the difficulties in performing the tasks and increase work productivity. For some of the technological innovations a digital scanner was used to generate a virtual solid model to facilitate its redesign and virtual prototyping. The main results show that organic farmers have little technology in product form. The main innovations that enable competitive advantage or allow higher labor productivity occur in the form of processes, organization and marketing.

  11. "Almost Darks": HI Mapping and Optical Analysis

    NASA Astrophysics Data System (ADS)

    Singer, Quinton; Ball, Catie; Cannon, John M.; Leisman, Luke; Haynes, Martha P.; Adams, Elizabeth A.; Bernal Neira, David; Giovanelli, Riccardo; Hallenbeck, Gregory L.; Janesh, William; Janowiecki, Steven; Jozsa, Gyula; Rhode, Katherine L.; Salzer, John Joseph

    2017-01-01

    We present VLA HI imaging of the "Almost Dark" galaxies AGC 227982, AGC 268363, and AGC 219533. Selected from the ALFALFA survey, "Almost Dark" galaxies have significant HI reservoirs but lack an obvious stellar counterpart in survey-depth ground-based optical imaging. These three HI-rich objects harbor some of the most extreme levels of suppressed star formation amongst the isolated sources in the ALFALFA catalog. Our new multi-configuration, high angular (~20") and spectral (1.7 km/s) resolution HI observations produce spatially resolved column density and velocity distribution moment maps. We compare these images to Sloan Digitized Sky Survey (SDSS) optical images. By localizing the HI gas, we identify previously unknown optical components (offset from the ALFALFA pointing center) for AGC 227982 and AGC 268363, and confirm the association with a very low surface brightness stellar counterpart for AGC 219533. Baryonic masses are derived from VLA flux integral values and ALFALFA distance estimates, giving answers consistent with those derived from ALFALFA fluxes. All three sources appear to have fairly regular HI morphologies and show evidence of ordered rotation.Support for this work was provided by NSF grant 1211683 to JMC at Macalester College.

  12. Using BIM Technology to Optimize the Traditional Interior Design Work Mode

    NASA Astrophysics Data System (ADS)

    Zhu, Ning Ke

    2018-06-01

    the development of BIM technology and application in the field of architecture design has produced results, but BIM technology and application in the field of interior design is still immaturity because of construction and decoration engineering separation. The article analyzes the problems that BIM technology lead to the interior design work mode optimization, from the 3D visualization work environment, real-time collaborative design mode, physical analysis design mode, information integration design mode state the application in interior design.

  13. High Technology School-to-Work Program at Argonne

    ScienceCinema

    None

    2018-02-14

    Argonne's High Technology School-to-Work Program for Chicago Public School Students. Supported by the Illinois Department of Commerce and Economic Opportunity, Chicago Public Schools, Argonne National Laboratory and the City of Chicago.

  14. Review of German work on controlled re-entry technology

    NASA Astrophysics Data System (ADS)

    Wuest, Walter

    The concept of a reusable space transporter formed a focus of much effort for the German firms Junkers Flugzeug- und Motorenwerke (JFM), Messerschmitt-Bölkow-Blohm und Voss (MBB) and Entwicklungsring Nord (ERNO), together with the Deutsche Forschungs- und Veruchsanstalt für Luft- und Raumfahrt (DFVLR) and different University institutes during the decade beginning 1962. The result was the definition, in 1972, of a program of the “Arbeitsgruppe Rückkehrtechnologie” (ART, Working group for reentry technology) which integrated all relevant capacities of research establishments, industry, and universities. The aim was the maintenance of the technical-scientific capabilities for advanced high velocity flight systems and to qualify for international cooperation in this field. Only a small part of this work could be completed, as the ART-program was never accepted by the German Ministry for Research and Technology. So the current work was stopped by the end of 1975. Nevertheless, as the ART-program can serve as a guide-line for possible future work a summary of this work is given.

  15. Technology, normalisation and male sex work.

    PubMed

    MacPhail, Catherine; Scott, John; Minichiello, Victor

    2015-01-01

    Technological change, particularly the growth of the Internet and smart phones, has increased the visibility of male escorts, expanded their client base and diversified the range of venues in which male sex work can take place. Specifically, the Internet has relocated some forms of male sex work away from the street and thereby increased market reach, visibility and access and the scope of sex work advertising. Using the online profiles of 257 male sex workers drawn from six of the largest websites advertising male sexual services in Australia, the role of the Internet in facilitating the normalisation of male sex work is discussed. Specifically we examine how engagement with the sex industry has been reconstituted in term of better informed consumer-seller decisions for both clients and sex workers. Rather than being seen as a 'deviant' activity, understood in terms of pathology or criminal activity, male sex work is increasingly presented as an everyday commodity in the market place. In this context, the management of risks associated with sex work has shifted from formalised social control to more informal practices conducted among online communities of clients and sex workers. We discuss the implications for health, legal and welfare responses within an empowerment paradigm.

  16. Dust recycling technology in Kimitsu Works

    NASA Astrophysics Data System (ADS)

    Oda, Hiroshi; Ibaraki, Tetsuharu

    Dust recycling technology by the rotary hearth furnace has been applied at Nippon Steel‧s Kimitsu Works since 2000. The dust and sludge with iron oxide and carbon are agglomerated into shaped articles and the iron oxide is reduced in a high temperature atmosphere. Zinc and other impurities in the dust and sludge are expelled and exhausted into off gas. The DRI pellets made from the dust and sludge have 70% metallization and are strong enough for being recycled to the blast furnaces. No.1 plant, which was constructed in May 2000 and has an agglomeration method of pelletizing, recycles mainly dry dusts. No.2 plant, which was constructed in December 2002 and has an agglomeration method of extrusion, recycles mainly sludge. The combination of the two plants is a solution for recycling various kinds of dusts and sludge emitted in a large scale steel works as Kimitsu Works

  17. Deep Learning-Based Data Forgery Detection in Automatic Generation Control

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Fengli; Li, Qinghua

    Automatic Generation Control (AGC) is a key control system in the power grid. It is used to calculate the Area Control Error (ACE) based on frequency and tie-line power flow between balancing areas, and then adjust power generation to maintain the power system frequency in an acceptable range. However, attackers might inject malicious frequency or tie-line power flow measurements to mislead AGC to do false generation correction which will harm the power grid operation. Such attacks are hard to be detected since they do not violate physical power system models. In this work, we propose algorithms based on Neural Networkmore » and Fourier Transform to detect data forgery attacks in AGC. Different from the few previous work that rely on accurate load prediction to detect data forgery, our solution only uses the ACE data already available in existing AGC systems. In particular, our solution learns the normal patterns of ACE time series and detects abnormal patterns caused by artificial attacks. Evaluations on the real ACE dataset show that our methods have high detection accuracy.« less

  18. Brave New Workplace: Technology and Work in the New Economy.

    ERIC Educational Resources Information Center

    Wallace, Michael

    1989-01-01

    Technological innovations in factories and offices are examined in terms of 10 core issues: "high flex" workplace; control of work; organizational change; impact on skill; unemployment; educational needs and retraining; changing occupational structures; safety and health; interaction of work, leisure, and family; and quality of working life. The…

  19. [Information technology and hospital care: reflection on the meaning of the work].

    PubMed

    Fonseca, Cláudia Maria Barboza Machado; dos Santos, Mônica Loureiro

    2007-01-01

    The purpose of this paper is to present the experience of nurses since the introduction of information technology in hospital work processes. It analyzes the meaning of information technology within the subjectivity and perception of healthcare in nursing work in a general hospital. As a theoretical background, it takes studies of work psychodynamics/psychopathology, referred to healthcare work processes and their repercussions on worker health. This qualitative inquiry strives to understand the significance of this subject in nursing routines. The field research was based on semi-structured interviews and non-systematic observation of some nursing activities, noting some resistance to change among the nurses, with difficulties in organizing the work and introducing them to new ways of handling their tasks. Faced by a machine, they feel trapped and isolated. This leads to the conclusion that the implementation of information technology interferes significantly in the work processes of the nurses participating in this study, and may adversely affect their health in the future.

  20. Examining Educational Climate Change Technology: How Group Inquiry Work with Realistic Scientific Technology Alters Classroom Learning

    NASA Astrophysics Data System (ADS)

    Bush, Drew; Sieber, Renee; Seiler, Gale; Chandler, Mark

    2018-04-01

    This study with 79 students in Montreal, Quebec, compared the educational use of a National Aeronautics and Space Administration (NASA) global climate model (GCM) to climate education technologies developed for classroom use that included simpler interfaces and processes. The goal was to show how differing climate education technologies succeed and fail at getting students to evolve in their understanding of anthropogenic global climate change (AGCC). Many available climate education technologies aim to convey key AGCC concepts or Earth systems processes; the educational GCM used here aims to teach students the methods and processes of global climate modeling. We hypothesized that challenges to learning about AGCC make authentic technology-enabled inquiry important in developing accurate understandings of not just the issue but how scientists research it. The goal was to determine if student learning trajectories differed between the comparison and treatment groups based on whether each climate education technology allowed authentic scientific research. We trace learning trajectories using pre/post exams, practice quizzes, and written student reflections. To examine the reasons for differing learning trajectories, we discuss student pre/post questionnaires, student exit interviews, and 535 min of recorded classroom video. Students who worked with a GCM demonstrated learning trajectories with larger gains, higher levels of engagement, and a better idea of how climate scientists conduct research. Students who worked with simpler climate education technologies scored lower in the course because of lower levels of engagement with inquiry processes that were perceived to not actually resemble the work of climate scientists.

  1. Nurses and health information technology: working with and around computers.

    PubMed

    Peace, Jane

    2011-01-01

    Information technology is nearly ubiquitous in health care settings. Nurses need basic computer skills and information literacy to effectively practice nursing. In addition, nurses must be prepared not only to work around complex health information technology, but also to communicate with individuals who can address the underlying problems.

  2. Programs for Middle School Math: An Inventory of Existing Technology. Working Paper

    ERIC Educational Resources Information Center

    Saultz, Andrew

    2012-01-01

    In this working paper, Andrew Saultz of Michigan State University inventories the current landscape of technology programs available for middle school math. The working paper is not intended as a "consumers' guide" to technology programs, and the descriptions of some specific programs are not fully accurate or current. Readers who are interested…

  3. Life and Work in a Technological Society. ERIC Digest No. 147.

    ERIC Educational Resources Information Center

    Kerka, Sandra

    Technology is more than applied science. It is the processes and products by which humans have coped with and changed their environment throughout history. People have always lived and worked in a "technological society." Never before, however, has technological change been so rapid or broad in scope. The concept of an "educated…

  4. Los Alamos Shows Airport Security Technology at Work

    ScienceCinema

    Espy, Michelle; Schultz, Larry; Hunter, James

    2018-05-30

    Los Alamos scientists have advanced a Magnetic Resonance Imaging (MRI) technology that may provide a breakthrough for screening liquids at airport security. They've added low-power X-ray data to the mix, and as a result have unlocked a new detection technology. Funded in part by the Department of Homeland Security's Science and Technology Directorate, the new system is named MagRay. The goal is to quickly and accurately distinguish between liquids that visually appear identical. For example, what appears to be a bottle of white wine could potentially be nitromethane, a liquid that could be used to make an explosive. Both are clear liquids, one would be perfectly safe on a commercial aircraft, the other would be strictly prohibited. How to tell them apart quickly without error at an airport security area is the focus of Michelle Espy, Larry Schultz and their team. In this video, Espy and the MagRay team explain how the new technology works, how they've developed an easy operator interface, and what the next steps might be in transitioning this technology to the private sector.

  5. Examining Middle School Students' Statistical Thinking While Working in a Technological Environment

    ERIC Educational Resources Information Center

    Scranton, Melissa Arnold

    2013-01-01

    The purpose of this study was to gain a better understanding of how students think in a technological environment. This was accomplished by exploring the differences in the thinking of students while they worked in a technological environment and comparing this to their work in a paper and pencil environment. The software program TinkerPlots:…

  6. AGC 2 Irradiated Material Properties Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rohrbaugh, David Thomas

    2017-05-01

    The Advanced Reactor Technologies Graphite Research and Development Program is conducting an extensive graphite irradiation experiment to provide data for licensing of a high temperature reactor (HTR) design. In past applications, graphite has been used effectively as a structural and moderator material in both research and commercial high temperature gas cooled reactor designs. , Nuclear graphite H 451, used previously in the United States for nuclear reactor graphite components, is no longer available. New nuclear graphite grades have been developed and are considered suitable candidates for new HTR reactor designs. To support the design and licensing of HTR core componentsmore » within a commercial reactor, a complete properties database must be developed for these current grades of graphite. Quantitative data on in service material performance are required for the physical, mechanical, and thermal properties of each graphite grade, with a specific emphasis on data accounting for the life limiting effects of irradiation creep on key physical properties of the HTR candidate graphite grades. Further details on the research and development activities and associated rationale required to qualify nuclear grade graphite for use within the HTR are documented in the graphite technology research and development plan.« less

  7. Mobility of Labour, Technological Transformations and the Right to Work.

    ERIC Educational Resources Information Center

    Gelpi, Ettore

    1985-01-01

    The author discusses the macro level of analysis and focuses on the nature of work within the world economy. He examines the cultural characteristics of work, the dynamics of international economic relations, the transformation of international relations, geographical mobility, technological transformation and immigration, professional mobility,…

  8. Los Alamos Shows Airport Security Technology at Work

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Espy, Michelle; Schultz, Larry; Hunter, James

    Los Alamos scientists have advanced a Magnetic Resonance Imaging (MRI) technology that may provide a breakthrough for screening liquids at airport security. They've added low-power X-ray data to the mix, and as a result have unlocked a new detection technology. Funded in part by the Department of Homeland Security's Science and Technology Directorate, the new system is named MagRay. The goal is to quickly and accurately distinguish between liquids that visually appear identical. For example, what appears to be a bottle of white wine could potentially be nitromethane, a liquid that could be used to make an explosive. Both aremore » clear liquids, one would be perfectly safe on a commercial aircraft, the other would be strictly prohibited. How to tell them apart quickly without error at an airport security area is the focus of Michelle Espy, Larry Schultz and their team. In this video, Espy and the MagRay team explain how the new technology works, how they've developed an easy operator interface, and what the next steps might be in transitioning this technology to the private sector.« less

  9. Plasma membrane proteins Slm1 and Slm2 mediate activation of the AGC kinase Ypk1 by TORC2 and sphingolipids in S. cerevisiae.

    PubMed

    Niles, Brad J; Powers, Ted

    2012-10-15

    The PH domain-containing proteins Slm1 and Slm2 were originally identified as substrates of the rapamycin-insensitive TOR complex 2 (TORC2) and as mediators of signaling by the lipid second messenger phosphatidyl-inositol-4,5-bisphosphate (PI4,5P2) in budding yeast S. cerevisiae. More recently, these proteins have been identified as critical effectors that facilitate phosphorylation and activation of the AGC kinases Ypk1 and Ypk2 by TORC2. Here, we review the molecular basis for this regulation as well as place it within the context of recent findings that have revealed Slm1/2 and TORC2-dependent phosphorylation of Ypk1 is coupled to the biosynthesis of complex sphingolipids and to their levels within the plasma membrane (PM) as well as other forms of PM stress. Together, these studies reveal the existence of an intricate homeostatic feedback mechanism, whereby the activity of these signaling components is linked to the biosynthesis of PM lipids according to cellular need.

  10. The relationship between work climate and nurse educators' use of information technology.

    PubMed

    Gonen, Ayala; Lev-Ari, Lilac

    2016-04-01

    Understanding organizational behavior and the attitudes of individuals in organizations is crucial for policymakers and managers. Work climate is a major part of these constructs. The main goal of this study was to examine the perceptions of academic nurse educators about their work climate, concerning the use of information technology (IT), including examining a number of variables such as self-efficacy, innovativeness, attitudes, intention to use, and actual use of information technology. This study used a quantitative research design, using written and online surveys submitted to 109 academic nurse educators working at ten different academic nursing schools in Israel. The relationship between work climate and actual use of IT was mediated by personality characteristics such as attitude toward using IT, self-efficacy, and innovativeness. Work climate positively predicted both self-efficacy and attitudes toward IT, but did not directly predict innovativeness and did not predict actual use. Policymakers and managers should consider work climate and personality characteristics as important factors in their efforts to promote IT use in nursing. As a result, nurse educators would become better acquainted with new technologies, and their acceptance of IT would improve. The organization would benefit from a better work environment and from enhanced performance. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Automated entry technologies for confined space work activities: A survey.

    PubMed

    Botti, Lucia; Ferrari, Emilio; Mora, Cristina

    2017-04-01

    Work in confined spaces poses a significant risk to workers and rescuers involved in the emergency response when an accident occurs. Despite several standards and regulations define the safety requirements for such activities, injuries, and fatalities still occur. Furthermore, the on-site inspections after accidents often reveal that both employers and employees fail to implement safe entry procedures. Removing the risk is possible by avoiding the worker entry, but many activities require the presence of the operator inside the confined space to perform manual tasks. The following study investigates the available technologies for hazardous confined space work activities, e.g., cleaning, inspecting, and maintenance tasks. The aim is to provide a systematic review of the automated solutions for high-risk activities in confined spaces, considering the non-man entry as the most effective confined space safety strategy. Second, this survey aims to provide suggestions for future research addressing the design of new technologies. The survey consists of about 60 papers concerning innovative technologies for confined space work activities. The document review shows that several solutions have been developed and automation can replace the workers for a limited number of hazardous tasks. Several activities still require the manual intervention due to the complex characteristics of confined spaces, e.g., to remove the remains of the automatic cleaning process from the bottom of a tank. The results show that available technologies require more flexibility to adapt to such occupational environments and further research is needed.

  12. New Forces at Work in Mining: Industry View of Critical Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Peterson, D. J.; LaTourrette, Tom; Bartis, James T.

    2007-04-01

    RAND has just published a report entitled, "New Forces at Work in Mining: Industry Views of Critical Technologies," by D. J. Peterson, Tom LaTourrette, and James T. Bartis. The report presents the results of a series of in-depth discussions with leading mining industry representatives selected for their prominent position and their ability to think broadly about technology trends. The discussions highlighted the importance of collaborative technology research, development, and implementation strategies and the increasingly critical role of mine personnel in the utilization of new technologies.

  13. Intimate Technology: A Tool for Teaching Anti-Racism in Social Work Education

    ERIC Educational Resources Information Center

    Deepak, Anne C.; Biggs, Mary Jo Garcia

    2011-01-01

    In this article, the authors introduce a new conceptual tool, intimate technology, to mobilize social work students' commitment to anti-racism. Intimate technology is marked by its emotional intensity and accessibility, and its effect of de-centering knowledge and authority. This teaching strategy integrates the modality of intimate technology via…

  14. How Undergraduate Students Use Social Media Technologies to Support Group Project Work

    ERIC Educational Resources Information Center

    McAliney, Peter J.

    2013-01-01

    Technology continues to evolve and become accessible to students in higher education. Concurrently, teamwork has become an important skill in academia and the workplace and students have adopted established technologies to support their learning in both individual and team project work. Given the emergence of social media technologies, I examined…

  15. 75 FR 57520 - NASA Advisory Council; Planetary Science Subcommittee; Supporting Research and Technology Working...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... Science Subcommittee; Supporting Research and Technology Working Group; Meeting AGENCY: National... announces a meeting of the Supporting Research and Technology Working Group of the Planetary Science... INFORMATION CONTACT: Dr. Michael New, Planetary Science Division, National Aeronautics and Space...

  16. Challenge 98: Sustaining the Work of a Regional Technology Integration Initiative

    ERIC Educational Resources Information Center

    Billig, Shelley H.; Sherry, Lorraine; Havelock, Bruce

    2005-01-01

    In this article, we offer a research-based theoretical framework for sustainability, describing the proven qualities of a project and the innovations that support its sustained existence over time. We then describe how a US Department of Education Technology Innovation Challenge grantee, working to promote technology integration in a…

  17. Technology Acceptance in Social Work Education: Implications for the Field Practicum

    ERIC Educational Resources Information Center

    Colvin, Alex Don; Bullock, Angela N.

    2014-01-01

    The exponential growth and sophistication of new information and computer technology (ICT) have greatly influenced human interactions and provided new metaphors for understanding the world. The acceptance and integration of ICT into social work field education are examined here using the technological acceptance model. This article also explores…

  18. How Technology Changes Demands for Human Skills. OECD Education Working Papers, No. 45

    ERIC Educational Resources Information Center

    Levy, Frank

    2010-01-01

    This paper places the competencies to be measured by the OECD's Programme for the International Assessment of Adult Competencies (PIAAC) in the context of the technological developments which are reshaping the nature of the workplace and work in the 21st century. The largest technological force currently shaping work is the computer. Computers are…

  19. Does This Really Work? The Keys to Implementing New Technology while Providing Evidence that Technology Is Successful

    ERIC Educational Resources Information Center

    Sawtelle, Sara

    2008-01-01

    Proving that technology works is not as simple as proving that a new vendor for art supplies is more cost effective. Technology effectiveness requires both the right software and the right implementation. Just having the software is not enough. Proper planning, training, leadership, support, pedagogy, and software use--along with many other…

  20. Social work, technology, and ethical practices: a review and evaluation of the national association of social workers' technology standards.

    PubMed

    Lopez, Amy

    2014-10-01

    Information and communication technologies (ICTs) are becoming essential to social work practice by providing increased treatment possibilities and reducing barriers to service. While recognizing the importance of ICTs in practice, social work practitioners have had concerns about ethical use. In response, NASW compiled the Standards for Technology and Social Work Practice. While the guidelines set the groundwork, they were not embedded in a process that would allow them to adapt to the swift pace of ICT changes. This article reviews the current Standards, evaluates how these have been implemented by practitioners, and offers suggestions for updates.

  1. Geophysical Technologies to Image Old Mine Works

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kanaan Hanna; Jim Pfeiffer

    2007-01-15

    ZapataEngineering, Blackhawk Division performed geophysical void detection demonstrations for the US Department of Labor Mine Safety and Health Administration (MSHA). The objective was to advance current state-of-practices of geophysical technologies for detecting underground mine voids. The presence of old mine works above, adjacent, or below an active mine presents major health and safety hazards to miners who have inadvertently cut into locations with such features. In addition, the presence of abandoned mines or voids beneath roadways and highway structures may greatly impact the performance of the transportation infrastructure in terms of cost and public safety. Roads constructed over abandoned minesmore » are subject to potential differential settlement, subsidence, sinkholes, and/or catastrophic collapse. Thus, there is a need to utilize geophysical imaging technologies to accurately locate old mine works. Several surface and borehole geophysical imaging methods and mapping techniques were employed at a known abandoned coal mine in eastern Illinois to investigate which method best map the location and extent of old works. These methods included: 1) high-resolution seismic (HRS) using compressional P-wave (HRPW) and S-wave (HRSW) reflection collected with 3-D techniques; 2) crosshole seismic tomography (XHT); 3) guided waves; 4) reverse vertical seismic profiling (RVSP); and 5) borehole sonar mapping. In addition, several exploration borings were drilled to confirm the presence of the imaged mine voids. The results indicated that the RVSP is the most viable method to accurately detect the subsurface voids with horizontal accuracy of two to five feet. This method was then applied at several other locations in Colorado with various topographic, geologic, and cultural settings for the same purpose. This paper presents the significant results obtained from the geophysical investigations in Illinois.« less

  2. A Review of Information and Communication Technology Enhanced Social Work Interventions

    ERIC Educational Resources Information Center

    Chan, Chitat; Holosko, Michael J.

    2016-01-01

    Objectives: Information and communications technology (ICT) has impacted almost all human service disciplines and currently is evolving in social work. This study provides a systematic review of ICT-enhanced social work interventions, with particular reference to their intervention fidelity (IF), validity, and the role of ICT in the helping…

  3. Impact of Collaborative Work on Technology Acceptance: A Case Study from Virtual Computing

    ERIC Educational Resources Information Center

    Konak, Abdullah; Kulturel-Konak, Sadan; Nasereddin, Mahdi; Bartolacci, Michael R.

    2017-01-01

    Aim/Purpose: This paper utilizes the Technology Acceptance Model (TAM) to examine the extent to which acceptance of Remote Virtual Computer Laboratories (RVCLs) is affected by students' technological backgrounds and the role of collaborative work. Background: RVCLs are widely used in information technology and cyber security education to provide…

  4. Opening the Box: Information Technology, Work Practices, and Wages.

    ERIC Educational Resources Information Center

    Hunter, Larry W.; Lakfas, John J.

    2003-01-01

    Analysis of 1994-95 data on customer service representatives in 303 banks revealed a positive relationship between high-involvement work practices (quality circles) and extensive use of information technology (IT) to support sales. Use of IT to automate routine processes and no quality circles were associated with lower wages. (Contains 55…

  5. Work Addiction and 21st Century Information Technologies in Traditional and Virtual Work Spaces in the United States

    ERIC Educational Resources Information Center

    Hunka, Patricia L.

    2014-01-01

    This study was completed to understand whether or not work addiction or work addiction intensity could be predicted from mobile technology use. The study further investigated whether or not gender, workspace, income, or education level would moderate the relationship. The sample used was drawn from service industry employees who are not in the…

  6. AGC 2 Irradiation Creep Strain Data Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Windes, William E.; Rohrbaugh, David T.; Swank, W. David

    2016-08-01

    The Advanced Reactor Technologies Graphite Research and Development Program is conducting an extensive graphite irradiation experiment to provide data for licensing of a high temperature reactor (HTR) design. In past applications, graphite has been used effectively as a structural and moderator material in both research and commercial high temperature gas cooled reactor designs. Nuclear graphite H-451, used previously in the United States for nuclear reactor graphite components, is no longer available. New nuclear graphite grades have been developed and are considered suitable candidates for new HTR reactor designs. To support the design and licensing of HTR core components within amore » commercial reactor, a complete properties database must be developed for these current grades of graphite. Quantitative data on in service material performance are required for the physical, mechanical, and thermal properties of each graphite grade, with a specific emphasis on data accounting for the life limiting effects of irradiation creep on key physical properties of the HTR candidate graphite grades. Further details on the research and development activities and associated rationale required to qualify nuclear grade graphite for use within the HTR are documented in the graphite technology research and development plan.« less

  7. The Impact of Technological Change on Work and Training. Tripartite European Meeting on the Impact of Technological Change on Work and Training (Geneva, Switzerland, October 28-November 2, 1991).

    ERIC Educational Resources Information Center

    International Labour Office, Geneva (Switzerland).

    The first part of this report examines the relationship of technological change to employment and work. After a brief introduction, chapter 1 discusses new technology and labor productivity versus employment, emphasizing the effects of labor-saving machinery and changes in specific sectors of employment, such as electrical machinery,…

  8. Using Technology with Classroom Instruction that Works. Second Edition

    ERIC Educational Resources Information Center

    Kuhn, Matt; Hubbell, Elizabeth R.; Pitler, Howard

    2012-01-01

    If you've upgraded to the second edition of the landmark book "Classroom Instruction That Works," you need this companion guide to help you use technology to support research-based instruction. The authors follow the revised Instructional Planning Guide that makes it easier for you to know when to emphasize each of the instructional strategies,…

  9. Changing Technology and Work: Northern Telecom. CAW Technology Project.

    ERIC Educational Resources Information Center

    Robertson, David; Wareham, Jeff

    A project to examine the implications of technological change at Northern Telecom consisted of two major components: a technological survey and case study research. A questionnaire that contained more than 90 questions on technological change was distributed through local union technology committee meetings in Brampton, London, Belleville, and…

  10. Publicly Owned Treatment Works (POTW): NESHAP Risk and Technology Review Final

    EPA Pesticide Factsheets

    These proposed amendments to the National Emission Standards for Hazardous Air Pollutants (NESHAP) for Publicly Owned Treatment Works (POTW) result from the results of the residual risk and technology review of that source category.

  11. Publicly Owned Treatment Works (POTW): NESHAP Risk and Technology Review Proposal

    EPA Pesticide Factsheets

    These proposed amendments to the National Emission Standards for Hazardous Air Pollutants (NESHAP) for Publicly Owned Treatment Works (POTW) result from the results of the residual risk and technology review of that source category.

  12. Long life technology work at Rockwell International Space Division

    NASA Technical Reports Server (NTRS)

    Huzel, D. K.

    1974-01-01

    This paper presents highlights of long-life technology oriented work performed at the Space Division of Rockwell International Corporation under contract to NASA. This effort included evaluation of Saturn V launch vehicle mechanical and electromechanical components for potential extended life capabilities, endurance tests, and accelerated aging experiments. A major aspect was evaluation of the components at the subassembly level (i.e., at the interface between moving surfaces) through in-depth wear analyses and assessments. Although some of this work is still in progress, preliminary conclusions are drawn and presented, together with the rationale for each. The paper concludes with a summary of the effort still remaining.

  13. ESTCP Munitions Response Live Site Demonstrations Southwest Proving Ground, Arkansas Andersen Air Force Base, Guam Cost and Performance Report

    DTIC Science & Technology

    2017-09-01

    CANNOT BE ANALYZED ....... 17  7.0  COST BENEFIT ANALYSIS...20  7.3  COST BENEFIT ...sites and assess the performance and cost benefits of implementing AGC technologies. OBJECTIVES OF THE DEMONSTRATION The demonstrations were

  14. Alternatives to Industrial Work Placement at Dublin Institute of Technology

    ERIC Educational Resources Information Center

    Bates, Catherine; Gamble, Elena

    2011-01-01

    In the current economic crisis, higher education graduates need transferable professional skills more than ever. They need resourcefulness, an ability to work reflectively, a sense of civic awareness and an impressive curriculum vitae. This case study analyses how Dublin Institute of Technology's Programme for Students Learning With Communities…

  15. VLA+WSRT HI Imaging of Two "Almost Dark" Galaxies

    NASA Astrophysics Data System (ADS)

    Ball, Catie; Singer, Quinton; Cannon, John M.; Leisman, Luke; Haynes, Martha P.; Adams, Elizabeth A.; Bernal Neira, David; Giovanelli, Riccardo; Hallenbeck, Gregory L.; Janesh, William; Janowiecki, Steven; Jozsa, Gyula; Rhode, Katherine L.; Salzer, John Joseph

    2017-01-01

    We present sensitive HI imaging of the "Almost Dark" galaxies AGC229385 and AGC229101. Selected from the ALFALFA survey, "Almost Dark" galaxies have significant HI reservoirs but lack an obvious stellar counterpart in survey-depth ground-based optical imaging. Deeper ground- and space-based imaging reveals very low surface brightness optical counterparts in both systems. The resulting M_HI/L_B ratios are among the highest ever measured for individual galaxies. Here we combine VLA and WSRT imaging of these two systems, allowing us to preserve surface brightness sensitivity while working at high angular resolution. The resulting maps of HI mass surface density, velocity field, and velocity dispersion are compared to deep optical and ultraviolet imaging. In both systems the highest column density HI gas is clumpy and resolved into multiple components. In the case of AGC229385, the kinematics are inconsistent with a simple rotating disk and may be the result of either an infall episode or an interaction between two HI-rich disks.Support for this work was provided by NSF grant 1211683 to JMC at Macalester College.

  16. Testing and Evaluating the Effectiveness of Advanced Technologies for Work Zones in Nevada

    DOT National Transportation Integrated Search

    2008-08-30

    The objective of this study was to evaluate two advanced technologies for improving safety in work zones: 1) speed monitoring display and 2) automatic work zone information system. In the evaluation of the speed monitoring display (also called a spee...

  17. Technology, Division of Labor and Alienation From Work. Final Report.

    ERIC Educational Resources Information Center

    Shepard, Jon M.

    This study investigated the theory that a worker's relationship to technology instills in him identifiable attitudes about work. Using samples of office workers from a bank and five insurance companies, and samples of factory workers from the oil refining and automobile industries, a total of 1,888 workers were divided into (1) office and factory…

  18. The Cellient automated cell block system is useful in the differential diagnosis of atypical glandular cells in Papanicolaou tests.

    PubMed

    Xing, Wei; Hou, April Y; Fischer, Andrew; Owens, Christopher L; Jiang, Zhong

    2014-01-01

    Atypical glandular cells (AGC) is a very important diagnosis in gynecological cytology. In the current study, the authors investigated the usefulness of Cellient cell blocks (CB) for characterizing AGC on Papanicolaou (Pap) tests. A total of 148 patients with an AGC diagnosis based on Pap tests by cytotechnologists and referred to cytopathologists were studied. Among these patients, there were 68 patients with CB preparations and 80 patients with Pap tests only (TP-AGC group). Follow-up results by Pap tests or biopsies were obtained in 117 of 148 patients. The median follow-up was 13 months (range, 1 month-36 months). Of the 68 patients with CBs, 31 (46%) were reclassified as negative for dysplasia or low-grade intraepithelial lesion; 30 patients (44%) retained a diagnosis of AGC (CB-AGC group); and 7 patients (10%) were given specific diagnoses of high-grade intraepithelial lesion (3 patients), endocervical adenocarcinoma in situ (1 patient), and invasive adenocarcinoma (3 patients). On follow-up, the CB-AGC group was found to have a significantly lower rate of negative/low-grade squamous intraepithelial lesion diagnoses compared with the TP-AGC group (55% vs 85%; P= .006). The CB-AGC group had a significantly higher rate of endocervical or endometrial adenocarcinoma compared with the TP-AGC group (36% vs 8%; P= .003) at the time of follow-up. The rates of high-grade squamous intraepithelial lesion were not found to be statistically different between these 2 groups (9% vs 7%; P= .66). The Cellient CB is a useful technique to further categorize a diagnosis of AGC on Pap tests. Using the Cellient CB system, the pathologist has the ability to improve the diagnostic accuracy of AGC so that unnecessary colposcopic evaluation or biopsies can be avoided. © 2013 American Cancer Society.

  19. 23 CFR 420.207 - What are the requirements for research, development, and technology transfer work programs?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., Development and Technology Transfer Program Management § 420.207 What are the requirements for research, development, and technology transfer work programs? (a) The State DOT's RD&T work program must, as a minimum... 23 Highways 1 2013-04-01 2013-04-01 false What are the requirements for research, development, and...

  20. 23 CFR 420.207 - What are the requirements for research, development, and technology transfer work programs?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., Development and Technology Transfer Program Management § 420.207 What are the requirements for research, development, and technology transfer work programs? (a) The State DOT's RD&T work program must, as a minimum... 23 Highways 1 2010-04-01 2010-04-01 false What are the requirements for research, development, and...

  1. 23 CFR 420.207 - What are the requirements for research, development, and technology transfer work programs?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., Development and Technology Transfer Program Management § 420.207 What are the requirements for research, development, and technology transfer work programs? (a) The State DOT's RD&T work program must, as a minimum... 23 Highways 1 2014-04-01 2014-04-01 false What are the requirements for research, development, and...

  2. 23 CFR 420.207 - What are the requirements for research, development, and technology transfer work programs?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., Development and Technology Transfer Program Management § 420.207 What are the requirements for research, development, and technology transfer work programs? (a) The State DOT's RD&T work program must, as a minimum... 23 Highways 1 2012-04-01 2012-04-01 false What are the requirements for research, development, and...

  3. 23 CFR 420.207 - What are the requirements for research, development, and technology transfer work programs?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., Development and Technology Transfer Program Management § 420.207 What are the requirements for research, development, and technology transfer work programs? (a) The State DOT's RD&T work program must, as a minimum... 23 Highways 1 2011-04-01 2011-04-01 false What are the requirements for research, development, and...

  4. Bridging the Skills Gap. Working Paper Part II: High Technology and Related Occupations.

    ERIC Educational Resources Information Center

    Kaplan, Christine E.

    This part of a 2-part working paper identifies and describes major occupational groups that are characteristic of high technology manufacturing and service industries as well as employment sectors that use high technology products in their provision of goods and services. The paper is based on a review of a wide range of employment projections…

  5. Voice Assessment of Student Work: Recent Studies and Emerging Technologies

    ERIC Educational Resources Information Center

    Eckhouse, Barry; Carroll, Rebecca

    2013-01-01

    Although relatively little attention has been given to the voice assessment of student work, at least when compared with more traditional forms of text-based review, the attention it has received strongly points to a promising form of review that has been hampered by the limits of an emerging technology. A fresh review of voice assessment in light…

  6. Knowledge management, health information technology and nurses' work engagement.

    PubMed

    Hendriks, Paul H J; Ligthart, Paul E M; Schouteten, Roel L J

    2016-01-01

    Knowledge management (KM) extends the health information technology (HIT) literature by addressing its impact on creating knowledge by sharing and using the knowledge of health care professionals in hospitals. The aim of the study was to provide insight into how HIT affects nurses' explicit and tacit knowledge of their ongoing work processes and work engagement. Data were collected from 74 nurses in four wards of a Dutch hospital via a paper-and-pencil survey using validated measurement instruments. In a quasiexperimental research design, HIT was introduced in the two experimental wards in contrast to the two control wards. At the time of the HIT introduction, a pretest was administered in all four wards and was followed by a posttest after 3 months. Data were analyzed via partial least squares modeling. Generally, nurses' tacit knowledge (i.e., their insight into and their capacity to make sense of the work processes) appears to be a significant and strong predictor of their work engagement. In contrast, nurses' explicit knowledge (i.e., information feedback about patients and tasks) only indirectly affects work engagement via its effect on tacit knowledge. Its effect on work engagement therefore depends on the mediating role of tacit knowledge. Interestingly, introducing HIT significantly affects only nurses' explicit knowledge, not their tacit knowledge or work engagement. Nurses' tacit and explicit knowledge needs to be systematically distinguished when implementing HIT/KM programs to increase work engagement in the workplace. Tacit knowledge (insight into work processes) appears to be pivotal, whereas efforts aimed only at improving available information will not lead to a higher level of work engagement in nurses' work environments.

  7. [Technology and future ways of thinking related to work from ergonomics points of views in moments of global crisis].

    PubMed

    Puentes-Lagos, David E; García-Acosta, Gabriel

    2012-06-01

    Is it possible to establish (at short, medium and long term) future work conditions or expected work conditions for Colombian people considering upcoming work technologies? Is it possible to anticipate future work desirable work conditions for Colombian people in order to plan (foresee?) work technologies? These questions guided this research and they point to an action thesis and to a reaction one in this context of work crisis. Even though a work technology establishes where, when, how, who, who with, and using what element work is done, it also establishes certain work conditions. Besides, multiple forms of considering and deconstructing past have been created from many disciplines. However, in order to foresee or construct work technologies requires a different perspective for looking further. This research has been carried out considering other disciplines points of view regarding Future Studies and Future Thinking Studies. This research has the purpose of finding future paths for Future Thinking Studies from ergonomics point of view in this moment of global work crisis we are going through.

  8. Deriving Requirements for Pervasive Well-Being Technology From Work Stress and Intervention Theory: Framework and Case Study

    PubMed Central

    Koldijk, Saskia; Kraaij, Wessel

    2016-01-01

    Background Stress in office environments is a big concern, often leading to burn-out. New technologies are emerging, such as easily available sensors, contextual reasoning, and electronic coaching (e-coaching) apps. In the Smart Reasoning for Well-being at Home and at Work (SWELL) project, we explore the potential of using such new pervasive technologies to provide support for the self-management of well-being, with a focus on individuals' stress-coping. Ideally, these new pervasive systems should be grounded in existing work stress and intervention theory. However, there is a large diversity of theories and they hardly provide explicit directions for technology design. Objective The aim of this paper is to present a comprehensive and concise framework that can be used to design pervasive technologies that support knowledge workers to decrease stress. Methods Based on a literature study we identify concepts relevant to well-being at work and select different work stress models to find causes of work stress that can be addressed. From a technical perspective, we then describe how sensors can be used to infer stress and the context in which it appears, and use intervention theory to further specify interventions that can be provided by means of pervasive technology. Results The resulting general framework relates several relevant theories: we relate “engagement and burn-out” to “stress”, and describe how relevant aspects can be quantified by means of sensors. We also outline underlying causes of work stress and how these can be addressed with interventions, in particular utilizing new technologies integrating behavioral change theory. Based upon this framework we were able to derive requirements for our case study, the pervasive SWELL system, and we implemented two prototypes. Small-scale user studies proved the value of the derived technology-supported interventions. Conclusions The presented framework can be used to systematically develop theory

  9. Deriving Requirements for Pervasive Well-Being Technology From Work Stress and Intervention Theory: Framework and Case Study.

    PubMed

    Koldijk, Saskia; Kraaij, Wessel; Neerincx, Mark A

    2016-07-05

    Stress in office environments is a big concern, often leading to burn-out. New technologies are emerging, such as easily available sensors, contextual reasoning, and electronic coaching (e-coaching) apps. In the Smart Reasoning for Well-being at Home and at Work (SWELL) project, we explore the potential of using such new pervasive technologies to provide support for the self-management of well-being, with a focus on individuals' stress-coping. Ideally, these new pervasive systems should be grounded in existing work stress and intervention theory. However, there is a large diversity of theories and they hardly provide explicit directions for technology design. The aim of this paper is to present a comprehensive and concise framework that can be used to design pervasive technologies that support knowledge workers to decrease stress. Based on a literature study we identify concepts relevant to well-being at work and select different work stress models to find causes of work stress that can be addressed. From a technical perspective, we then describe how sensors can be used to infer stress and the context in which it appears, and use intervention theory to further specify interventions that can be provided by means of pervasive technology. The resulting general framework relates several relevant theories: we relate "engagement and burn-out" to "stress", and describe how relevant aspects can be quantified by means of sensors. We also outline underlying causes of work stress and how these can be addressed with interventions, in particular utilizing new technologies integrating behavioral change theory. Based upon this framework we were able to derive requirements for our case study, the pervasive SWELL system, and we implemented two prototypes. Small-scale user studies proved the value of the derived technology-supported interventions. The presented framework can be used to systematically develop theory-based technology-supported interventions to address work stress. In

  10. Working Group 5: Measurements technology and active experiments

    NASA Technical Reports Server (NTRS)

    Whipple, E.; Barfield, J. N.; Faelthammar, C.-G.; Feynman, J.; Quinn, J. N.; Roberts, W.; Stone, N.; Taylor, W. L.

    1986-01-01

    Technology issues identified by working groups 5 are listed. (1) New instruments are needed to upgrade the ability to measure plasma properties in space. (2) Facilities should be developed for conducting a broad range of plasma experiments in space. (3) The ability to predict plasma weather within magnetospheres should be improved and a capability to modify plasma weather developed. (4) Methods of control of plasma spacecraft and spacecraft plasma interference should be upgraded. (5) The space station laboratory facilities should be designed with attention to problems of flexibility to allow for future growth. These issues are discussed.

  11. Object and technologies in the working process of an itinerant team in mental health.

    PubMed

    Eslabão, Adriane Domingues; Pinho, Leandro Barbosa de; Coimbra, Valéria Cristina Christello; Lima, Maria Alice Dias da Silva; Camatta, Marcio Wagner; Santos, Elitiele Ortiz Dos

    2017-01-01

    Objective To analyze the work object and the technologies in the working process of a Mental Health Itinerant Team in the attention to drug users. Methods Qualitative case study, carried out in a municipality in the South of Brazil. The theoretical framework was the Healthcare Labor Process. The data was collected through participant observation and semi-structured interviews with the professionals of an itinerant team in the year of 2015. For data analysis we used the Thematic Content Analysis. Results In the first empirical category - work object - the user is considered as a focus, bringing new challenges in the team's relationship with the network. In the second category - technologies of the work process - potentialities and contradictions of the team work tools are highlighted. Conclusions As an innovation in the mental health context, the itinerant team brings real possibilities to reinvent the care for the drug user as well as new institutional challenges.

  12. The Diffusion of Information Technology in the Human Services: Implications for Social Work Education

    ERIC Educational Resources Information Center

    Fitch, Dale

    2005-01-01

    The spread and utilization of information technology in the human services is examined using innovation diffusion theory. This examination is contextualized within the values basis of social work. Literature from the human services, the business sector, and the social sciences regarding the role of information technology is used to promote a…

  13. OECD Work on Technology and Education: Innovative Learning Environments as an Integrating Framework

    ERIC Educational Resources Information Center

    Istance, David; Kools, Marco

    2013-01-01

    This article presents in summary a selection of the work conducted by OECD in the field of technology and education, which has been an on-going focus of OECD work since the 1980s. Recently, much of this has been under the heading of "New Millennium Learners", but it has also included the widening of student achievement surveys towards…

  14. Center Director Bridges visits Disability Awareness and Action working Group Technology Fair

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Center Director Roy Bridges (standing, center) poses with members of the Disability Awareness and Action Working Group (DAAWG), which is holding the 1999 Technology Fair Oct. 20-21 at Kennedy Space Center. The Fair is highlighting vendors demonstrating mobility, hearing, vision and silent disability assistive technology. The purpose is to create an awareness of the types of technology currently available to assist people with various disabilities in the workplace. The theme is that of this year's National Disability Employment Awareness Month, 'Opening Doors to Ability.' Some of the vendors participating are Canine Companions for Independence, Goodwill Industries, Accessible Structures, Division of Blind Services, Space Coast Center for Independent Living, KSC Fitness Center and Delaware North Parks Services.

  15. Technologies That Assist in Online Group Work: A Comparison of Synchronous and Asynchronous Computer Mediated Communication Technologies on Students' Learning and Community

    ERIC Educational Resources Information Center

    Rockinson-Szapkiw, Amanda; Wendt, Jillian

    2015-01-01

    While the benefits of online group work completed using asynchronous CMC technology is documented, researchers have identified a number of challenges that result in ineffective and unsuccessful online group work. Fewer channels of communication and lack of immediacy when compared to face-to-face group work are a few of the noted limitations. Thus,…

  16. The Berry Informational Technology (B.I.T.S.) Student Work Program: An Effective Environment for Collaborative Learning, Leadership, Technological Training, and Certification.

    ERIC Educational Resources Information Center

    Cornelius, Amy; Macaluso, Paul

    The Berry Informational Technology (B.I.T.S.) program at Berry College (Georgia) is an apprenticeship opportunity associated with student work. The program gives students the opportunity to seek technological training in areas, such as building computer systems, trouble-shooting, networking, Web development, and user and technical support. In…

  17. Hyperelastic antiplane ground cloaking

    NASA Astrophysics Data System (ADS)

    Zhang, Pu; Parnell, William J.

    2018-05-01

    Hyperelastic materials possess the appealing property that they may be employed as elastic wave manipulation devices and cloaks by imposing pre-deformation. They provide an alternative to microstructured metamaterials and can be used in a reconfigurable manner. Previous studies indicate that exact elastodynamic invariance to pre-deformation holds only for neo-Hookean solids in the antiplane wave scenario and the semi-linear material in the in-plane compressional/shear wave context. Furthermore, although ground cloaks have been considered in the acoustic context they have not yet been discussed for elastodynamics, either by employing microstructured cloaks or hyperelastic cloaks. This work therefore aims at exploring the possibility of employing a range of hyperelastic materials for use as antiplane ground cloaks (AGCs). The use of the popular incompressible Arruda-Boyce and Mooney-Rivlin nonlinear materials is explored. The scattering problem associated with the AGC is simulated via finite element analysis where the cloaked region is formed by an indentation of the surface. Results demonstrate that the neo-Hookean medium can be used to generate a perfect hyperelastic AGC as should be expected. Furthermore, although the AGC performance of the Mooney-Rivlin material is not particularly satisfactory, it is shown that the Arruda-Boyce medium is an excellent candidate material for this purpose.

  18. Digital Technology in Mathematics Education: Why It Works (Or Doesn't)

    ERIC Educational Resources Information Center

    Drijvers, Paul

    2013-01-01

    The integration of digital technology confronts teachers, educators and researchers with many questions. What is the potential of ICT for learning and teaching, and which factors are decisive in making it work in the mathematics classroom? To investigate these questions, six cases from leading studies in the field are described, and decisive…

  19. Bridging the Skills Gap. Working Paper Part I: High Technology Industries.

    ERIC Educational Resources Information Center

    Kaplan, Christine E.

    In this working paper on high technology industries, a few representative industries are studied in detail, while an overview is also given of the group as a whole. The overview, which highlights the findings of selected studies of the unique characteristics of high tech industries, considers such issues as locational factors, occupational and…

  20. Technology Works in the Outdoors

    ERIC Educational Resources Information Center

    Zita, Adam

    2008-01-01

    Technology is all around us and no matter how hard educators promote the value of outdoor and experiential education (OEE) to adults and children alike, they are pulled away by a different reality--one might say, a virtual reality. Even when one is engaged in the outdoors either through a night hike or a stream study, technology is lingering…

  1. Targeted therapies in gastric cancer and future perspectives.

    PubMed

    Yazici, Ozan; Sendur, M Ali Nahit; Ozdemir, Nuriye; Aksoy, Sercan

    2016-01-14

    Advanced gastric cancer (AGC) is associated with a high mortality rate and, despite multiple new chemotherapy options, the survival rates of patients with AGC remains poor. After the discovery of targeted therapies, research has focused on the new treatment options for AGC. In the last two decades, many targeted molecules were developed against AGC. Currently, two targeted therapy molecules have been approved for patients with AGC. In 2010, trastuzumab was the first molecule shown to improve survival in patients with HER2-positive AGC as part of a first-line combination regimen. In 2014, ramucirumab was the second targeted molecule to improve survival rates and was suggested as treatment for patients with AGC who had progressed after first-line platinum plus fluoropyrimidine with or without anthracycline chemotherapy. Ramucirumab was the first targeted therapy acting as a single agent in patients with advanced gastroesophageal cancers. Although these two molecules were introduced into clinical use, many other promising molecules have been tested in phase I-II trials. It is obvious that in the near future many different targeted therapies will be in use for treatment of AGC. In this review, the current status of targeted therapies in the treatment of AGC and gastroesophageal junction tumors, including HER (2-3) inhibitors, epidermal growth factor receptor inhibitors, tyrosine kinase inhibitors, antiangiogenic agents, c-MET inhibitors, mammalian target of rapamycin inhibitors, agents against other molecular pathways fibroblast growth factor, Claudins, insulin-like growth factor, heat shock proteins, and immunotherapy, will be discussed.

  2. Spectroscopic characterization of the effect of gamma radiation on the physical parameters of biosynthesized silver/chitosan nano-particles and their antimicrobial activity

    NASA Astrophysics Data System (ADS)

    Osman, Mohamed E.; Eid, May M.; Khattab, Om kolthoum H.; El-Hallouty, Salwa M.; El-Marakby, Seham M.; Mahmoud, Doaa A.

    2015-09-01

    Studying the effect of pH on the biosynthesis of silver/chitosan nanoparticles (Ag/CS NPs) using Aspergillus deflectus and Penicillium pinophilum as reducing agents, showed very weak surface plasmon resonance (SPR) of Ag/CS NPs at certain pH. In this paper, the effect of irradiation on the synthesis of Ag/CS at non-optimum pH was evaluated and thereby, the antimicrobial effect of the biosynthesized Ag/CS NPs. The SPR of the AgNPs was analyzed by UV-visible spectroscopy. The active groups responsible for the reduction and capping of the AgNPs were analyzed by Fourier transform infrared (FTIR), and their shape and size were determined via high resolution transmission electron microscopy (HRTEM) and the dynamic light scattering (DLS) technique. UV/Visible spectroscopy confirmed the appearance of AgNPs’ SPR. Additionally, the FTIR spectroscopy confirmed the Ag/CS NP formation. Data also revealed that increasing both the pH and irradiation dose resulted in a decrease of the Ag/CS NPs’ size. DLS and HRTEM results showed that the best pH for biosynthesis of Ag/Cs is 7.5 at 50 kGy considering the particle size and crystallinity. Also, pH 8.5 gave the best antimicrobial activity of the Ag/CS NPs from Penicillium against both S. aureus and E. coli, while 8.5 and 7.5 were the best in the same order, for Ag/CS from Aspergillus.

  3. Identifying the Ethical Challenges Encountered by Information Technology Professionals Working within the Nevada Casino Industry

    ERIC Educational Resources Information Center

    Essig, Michael R.

    2014-01-01

    A thematic analysis qualitative study was used to identify the unethical challenges encountered by Information Technology (IT) professionals working within the Nevada casino industry. Fourteen current and former IT leaders working or who worked in the Nevada casino industry were interviewed. Using thematic analysis, nine themes regarding ethical…

  4. The Future of Work: Technology Beckons

    ERIC Educational Resources Information Center

    Donlevy, Jim

    2005-01-01

    In the schools, each day, teachers see cell phones, laptops, iPods, personal digital assistants, computer games and more. They are struggling to cope with this technological profusion as new devices seem to appear almost daily. With the pace of technological change, the emergence of new technologies, demographic changes and trends towards…

  5. Technology-based interventions in social work practice: a systematic review of mental health interventions.

    PubMed

    Ramsey, Alex T; Montgomery, Katherine

    2014-10-01

    Despite concerns around the use of technology-based interventions, they are increasingly being employed by social workers as a direct practice methodology to address the mental health needs of vulnerable clients. Researchers have highlighted the importance of using innovative technologies within social work practice, yet little has been done to summarize the evidence and collectively assess findings. In this systematic review, we describe accounts of technology-based mental health interventions delivered by social workers over the past 10 years. Results highlight the impacts of these tools and summarize advantages and disadvantages to utilizing technologies as a method for delivering or facilitating interventions.

  6. Real power regulation for the utility power grid via responsive loads

    DOEpatents

    McIntyre, Timothy J [Knoxville, TN; Kirby, Brendan J [Knoxville, TN; Kisner, Roger A

    2009-05-19

    A system for dynamically managing an electrical power system that determines measures of performance and control criteria for the electric power system, collects at least one automatic generation control (AGC) input parameter to at least one AGC module and at least one automatic load control (ALC) input parameter to at least one ALC module, calculates AGC control signals and loads as resources (LAR) control signals in response to said measures of performance and control criteria, propagates AGC control signals to power generating units in response to control logic in AGC modules, and propagates LAR control signals to at least one LAR in response to control logic in ALC modules.

  7. Technological Health Intervention in Population Aging to Assist People to Work Smarter not Harder: Qualitative Study

    PubMed Central

    2018-01-01

    Background Technology-based health care has been promoted as an effective tool to enable clinicians to work smarter. However, some health stakeholders believe technology will compel users to work harder by creating extra work. Objective The objective of this study was to investigate how and why electronic health (eHealth) has been applied in Taiwan and to suggest implications that may inspire other countries facing similar challenges. Methods A qualitative methodology was adopted to obtain insightful inputs from deeper probing. Taiwan was selected as a typical case study, given its aging population, advanced technology, and comprehensive health care system. This study investigated 38 stakeholders in the health care ecosystem through in-depth interviews and focus groups, which provides an open, flexible, and enlightening way to study complex, dynamic, and interactive situations through informal conversation or a more structured, directed discussion. Results First, respondents indicated that the use of technology can enable seamless patient care and clinical benefits such as flexibility in time management. Second, the results suggested that a leader’s vision, authority, and management skills might influence success in health care innovation. Finally, the results implied that both internal and external organizational governance are highly relevant for implementing technology-based innovation in health care. Conclusions This study provided Taiwanese perspectives on how to intelligently use technology to benefit health care and debated the perception that technology prevents human interaction between clinicians and patients. PMID:29301736

  8. [Work ability among workers from a condominiun of high technology companies].

    PubMed

    Fernandes, Angela Cristina Puzzi; Monteiro, Maria Inês

    2006-01-01

    Remarkable transformation occurred in the last two decades on the industrial sector, such as the use of trainees and outsourced labor. In a epidemiological cross-sectional study 190 workers, aimed at assessing work ability and building up a socio-demographic life styles of workers, outsourced workers and trainees, who work at a corporate condominium comprising high technology companies. The Work Ability Index was employed with a questionnaire concerning lifestyle and demographic data. Gender balance was noticed, with a prevalence of youngsters and single people (63.2%). Few were tobacco smokers (13.2%), 62.6% performed physical exercise. In addition, 44.2% were medically diagnosed with some illness. This study is very important due to their interchangeability and to the general lack of a worker's health service.

  9. Dual Arm Work Platform teleoperated robotics system. Innovative technology summary report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    The US Department of Energy (DOE) and the Federal Energy Technology Center (FETC) has developed a Large Scale Demonstration Project (LSDP) at the Chicago Pile-5 Research Reactor (CP-5) at Argonne National Laboratory-East (ANL). The objective of the LSDP is to demonstrate potentially beneficial Deactivation and Decommissioning (D and D) technologies in comparison with current baseline technologies. The Dual Arm Work Platform (DAWP) demonstration focused on the use of the DAWP to segment and dismantle the CP-5 reactor tank and surrounding bio-shield components (including the graphite block reflector, lead and boral sheeting) and performing some minor tasks best suited for themore » use of teleoperated robotics that were not evaluated in this demonstration. The DAWP system is not a commercially available product at this time. The CP-5 implementation was its first D and D application. The demonstration of the DAWP was to determine the areas on which improvements must be made to make this technology commercially viable. The results of the demonstration are included in this greenbook. It is the intention of the developers to incorporate lessons learned at this demonstration and current technological advancements in robotics into the next generation of the DAWP.« less

  10. WORK PLAN FOR COMPLETING A TECHNOLOGY ASSESSMENT OF WESTERN ENERGY RESOURCE DEVELOPMENT

    EPA Science Inventory

    This is a work plan for completing the final phase of a three year technology assessment of the development of six energy resources (coal, geothermal, natural gas, oil, oil shale, and uranium) in eight western states (Arizona, Colorado, Montana, New Mexico, North and South Dakota...

  11. Technology-based Interventions in Social Work Practice: A Systematic Review of Mental Health Interventions

    PubMed Central

    Montgomery, Katherine

    2014-01-01

    Despite concerns around the use of technology-based interventions, they are increasingly being employed by social workers as a direct practice methodology to address the mental health needs of vulnerable clients. Researchers have highlighted the importance of using innovative technologies within social work practice, yet little has been done to summarize the evidence and collectively assess findings. In this systematic review, we describe accounts of technology-based mental health interventions delivered by social workers over the past 10 years. Results highlight the impacts of these tools and summarize advantages and disadvantages to utilizing technologies as a method for delivering or facilitating interventions. PMID:25321935

  12. Ergonomics and quality management--humans in interaction with technology, work environment, and organization.

    PubMed

    Eklund, J A

    1999-01-01

    In many studies, ergonomics has been shown to influence human performance. The aim of this paper was to demonstrate important ergonomics influences on quality in industrial production, from the perspective of interactions between humans, technology, organization, and work environment. A second aim was to elaborate on the implications of these findings for the development of quality management strategies. This paper shows that ergonomics problems in terms of adverse work environmental conditions, inappropriate design of technology, and an unsuitable organization are important causes of quality deficiencies. Problem solving aimed at improving ergonomics, quality, and productivity simultaneously is likely to obtain support from most of the interest parties of the company, and may also enhance participation. Ergonomics has the potential of becoming a driving force for the development of new quality management strategies.

  13. Technological Health Intervention in Population Aging to Assist People to Work Smarter not Harder: Qualitative Study.

    PubMed

    Chen, Sonia Chien-I

    2018-01-04

    Technology-based health care has been promoted as an effective tool to enable clinicians to work smarter. However, some health stakeholders believe technology will compel users to work harder by creating extra work. The objective of this study was to investigate how and why electronic health (eHealth) has been applied in Taiwan and to suggest implications that may inspire other countries facing similar challenges. A qualitative methodology was adopted to obtain insightful inputs from deeper probing. Taiwan was selected as a typical case study, given its aging population, advanced technology, and comprehensive health care system. This study investigated 38 stakeholders in the health care ecosystem through in-depth interviews and focus groups, which provides an open, flexible, and enlightening way to study complex, dynamic, and interactive situations through informal conversation or a more structured, directed discussion. First, respondents indicated that the use of technology can enable seamless patient care and clinical benefits such as flexibility in time management. Second, the results suggested that a leader's vision, authority, and management skills might influence success in health care innovation. Finally, the results implied that both internal and external organizational governance are highly relevant for implementing technology-based innovation in health care. This study provided Taiwanese perspectives on how to intelligently use technology to benefit health care and debated the perception that technology prevents human interaction between clinicians and patients. ©Sonia Chien-I Chen. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 04.01.2018.

  14. Analyses of atypical glandular cells re-defined by the 2006 Bethesda System: histologic outcomes and clinical implication of follow-up management.

    PubMed

    Ulker, V; Numanoglu, C; Akyol, A; Kuru, O; Akbayir, O; Erim, A; Ongut, C

    2013-01-01

    To evaluate the histopathology and the long-term follow-up outcome of women who had atypical glandular cells on Pap smears. All women with atypical glandular cells (AGC) who underwent colposcopic and histopathologic evaluation between January 2005 and October 2010 were reviewed. Patient data were examined up to October 2012, allowing for at least two years of follow-up for all patients. Forty-four women with AGC Pap test underwent histologic follow-up during the study period. Overall, upon reclassification of smears, 35 (79.5%) cases were diagnosed with AGC "not otherwise specified" (NOS) and nine (20.5%) with AGC "favour neoplasia". Seven out of nine patients (77.7%) with AGC "favour neoplasia" had significant pathology. On the other hand, only 11 out of 35 cases (31.4%) with AGC "NOS" had significant pathology. Significant correlation was found between AGC "favour neoplasia" smears and a significant pathology (p: 0.01). Of the 44 patients, 18 (40.9%) had significant pathology. Eight patients (18.2%) had low grade cervical intraepithelial neoplasia (CIN 1), four (9%) had high-grade cervical intraepithelial neoplasia (CIN 2/3), one (2.2%) had microinvasive squamous cell carcinoma of uterine cervix, one (2.2%) had cervical adenocarcinoma in situ, one (2.2%) had cervical adenocarcinoma, one (2.2%) had endometrial adenocarcinoma, and two (4.5%) had endometrial hyperplasia. Reporting AGC in the population is clinically significant due to the high prevalence of underlying preinvasive and invasive diseases (40.9%). The subtypes of the AGC category are significant predictor of such lesions.

  15. Integrated Short Range, Low Bandwidth, Wearable Communications Networking Technologies

    DTIC Science & Technology

    2012-04-30

    Only (FOUO) Table of Contents Introduction 7 Research Discussions 7 1 Specifications 8 2 SAN Radio 9 2.1 R.F. Design Improvements 9 2.1.1 LNA...Characterization and Verification Testing 26 2.2 Digital Design Improvements 26 2.2.1 Improve Processor Access to Memory Resources 26 2.2.2...integrated and tested . A hybrid architecture of the automatic gain control (AGC) was designed to Page 7 of 116 For Official Use Only (FOUO

  16. Defining the Genetic Features of O-Antigen Biosynthesis Gene Cluster and Performance of an O-Antigen Serotyping Scheme for Escherichia albertii.

    PubMed

    Wang, Hong; Zheng, Han; Li, Qun; Xu, Yanmei; Wang, Jianping; Du, Pengcheng; Li, Xinqiong; Liu, Xiang; Zhang, Ling; Zou, Nianli; Yan, Guodong; Zhang, Zhengdong; Jing, Huaiqi; Xu, Jianguo; Xiong, Yanwen

    2017-01-01

    Escherichia albertii is a newly described and emerging diarrheagenic pathogen responsible for outbreaks of gastroenteritis. Serotyping plays an important role in diagnosis and epidemiological studies for pathogens of public health importance. The diversity of O-antigen biosynthesis gene clusters (O-AGCs) provides the primary basis for serotyping. However, little is known about the distribution and diversity of O-AGCs of E. albertii strains. Here, we presented a complete sequence set for the O-AGCs from 52 E. albertii strains and identified seven distinct O-AGCs. Six of these were also found in 15 genomes of E. albertii strains deposited in the public database. Possession of wzy / wzx genes in each O-AGC strongly suggest that O-antigens of E. albertii were synthesized by the Wzx/Wzy-dependent pathway. Furthermore, we performed an O-antigen serotyping scheme for E. albertii based on specific antisera against seven O-antigens and a high throughput xTAG Luminex assay to simultaneously detect seven O-AGCs. Both methods accurately identified serotypes of 64 tested E. albertii strains. Our data revealed the high-level diversity of O-AGCs in E. albertii . We also provide valuable methods to reliably identify and serotype this bacterium.

  17. Usage of DNA Fingerprinting Technology for Quality Control in Molecular Lab Bench Work.

    PubMed

    McIntosh, Linda Y; Lal, Janella E; Qin, Dahui

    2018-01-01

    One of the major quality assurance (QA) goals in many molecular laboratories is to avoid sample pipetting errors on the lab bench; especially when pipetting into multiwell plates. A pipetting error can cause a switch in patient samples, which can lead to recording the wrong results for the patient samples involved. Such pipetting errors are difficult to identify when it happens in lab bench work. DNA fingerprinting is a powerful tool in determining sample identities. Our laboratory has explored the usage of this technology in our QA process and successfully established that DNA fingerprinting can be used to monitor possible sample switch in gene rearrangement lab bench work. We use florescent light to quench the florescence in the gene rearrangement polymerase chain reaction products. After that, DNA fingerprinting technology is used to identify the sample DNA in the gene rearrangement polymerase chain reaction plate. The result is compared with the corresponding patient's blood sample DNA to determine whether there is a sample switch during the lab bench work.

  18. A critical analysis of the cytoreductive surgery with hyperthermic intraperitoneal chemotherapy combo in the clinical management of advanced gastric cancer: an effective multimodality approach with scope for improvement

    PubMed Central

    Beeharry, Maneesh K.; Liu, Wen-Tao; Yao, Xue-Xin

    2016-01-01

    Peritoneal carcinomatosis (PC) is manifested in up to 40% of gastric cancer (GC) patients, after which their 5-year survival drops to less than 5%. The currently most acceptable treatment option for advanced GC (AGC) is systemic chemo and radio therapies with however generally very unsatisfying results and this led to a resurgence of interest in regional therapies like cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Small trials have indicated an association with prolonged survival when applying this technique to AGC manifesting with PC. High procedure-related morbidity and mortality associated with the CRS-HIPEC approach have however brought by a polemic on the merits of the latter: with the advent of regulatory approval of more effective as well as novel, more personalized treatment options in AGC, along with advances in tailoring investigational agents specifically for peritoneal delivery, there clearly is a need to outline the appropriate role of CRS-HIPEC in this disease. In a clear objective to improve the therapeutic efficiency of HIPEC, there have been immense developments in the technical aspects of this technology including the use of nanotechnology in more precise drug delivery systems (DDS) or choice of more efficient drugs such as gene-target technology, laparoscopy and so on. Henceforth, in this review, we will be highlighting the past and current status of the CRS + HIPEC procedure, shedding light on the pros and cons in order to boost up the efficiency of this multimodality approach. PMID:28138643

  19. A critical analysis of the cytoreductive surgery with hyperthermic intraperitoneal chemotherapy combo in the clinical management of advanced gastric cancer: an effective multimodality approach with scope for improvement.

    PubMed

    Beeharry, Maneesh K; Liu, Wen-Tao; Yao, Xue-Xin; Yan, Min; Zhu, Zheng-Gang

    2016-01-01

    Peritoneal carcinomatosis (PC) is manifested in up to 40% of gastric cancer (GC) patients, after which their 5-year survival drops to less than 5%. The currently most acceptable treatment option for advanced GC (AGC) is systemic chemo and radio therapies with however generally very unsatisfying results and this led to a resurgence of interest in regional therapies like cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Small trials have indicated an association with prolonged survival when applying this technique to AGC manifesting with PC. High procedure-related morbidity and mortality associated with the CRS-HIPEC approach have however brought by a polemic on the merits of the latter: with the advent of regulatory approval of more effective as well as novel, more personalized treatment options in AGC, along with advances in tailoring investigational agents specifically for peritoneal delivery, there clearly is a need to outline the appropriate role of CRS-HIPEC in this disease. In a clear objective to improve the therapeutic efficiency of HIPEC, there have been immense developments in the technical aspects of this technology including the use of nanotechnology in more precise drug delivery systems (DDS) or choice of more efficient drugs such as gene-target technology, laparoscopy and so on. Henceforth, in this review, we will be highlighting the past and current status of the CRS + HIPEC procedure, shedding light on the pros and cons in order to boost up the efficiency of this multimodality approach.

  20. Understanding the Impact of New Technology on Life and Work. Learning Guide 12. Project Connect. Linking Self-Family-Work.

    ERIC Educational Resources Information Center

    Emily Hall Tremaine Foundation, Inc., Hartford, CT.

    This learning guide on understanding the impact of new technology on life and work is part of a series of learning guides developed for competency-based adult consumer and homemaking education programs in community colleges, adult education centers, community centers, and the workplace. Focus is on the connections among personal, family, and job…

  1. History and Development of Instructional Technology and Media in Social Work Education

    ERIC Educational Resources Information Center

    Shorkey, Clayton T.; Uebel, Michael

    2014-01-01

    Since the mid-20th century, instructional technologies and educational media in social work education have undergone significant development with the goals of improving learning and performance and enhancing access. This growth has been marked by technical advances in hardware and by innovations in media, or so-called soft formats. Current…

  2. Job Change and Workplace Learning in the Public Sector: The Significance of New Technology for Unskilled Work.

    ERIC Educational Resources Information Center

    Munro, Anne; Rainbird, Helen

    2002-01-01

    Interviews (n=350) and a survey (n=323) of managers, trainers, and union representatives in British health care agencies showed that technology caused some job enlargement and enrichment; positive or negative effects depended on context. Other jobs were deskilled due to work organization, not technology. Technology's impact on job change was…

  3. Solving challenges in inter- and trans-disciplinary working teams: Lessons from the surgical technology field.

    PubMed

    Korb, Werner; Geißler, Norman; Strauß, Gero

    2015-03-01

    Engineering a medical technology is a complex process, therefore it is important to include experts from different scientific fields. This is particularly true for the development of surgical technology, where the relevant scientific fields are surgery (medicine) and engineering (electrical engineering, mechanical engineering, computer science, etc.). Furthermore, the scientific field of human factors is important to ensure that a surgical technology is indeed functional, process-oriented, effective, efficient as well as user- and patient-oriented. Working in such trans- and inter-disciplinary teams can be challenging due to different working cultures. The intention of this paper is to propose an innovative cooperative working culture for the interdisciplinary field of computer-assisted surgery (CAS) based on more than ten years of research on the one hand and the interdisciplinary literature on working cultures and various organizational theories on the other hand. In this paper, a retrospective analysis of more than ten years of research work in inter- and trans-disciplinary teams in the field of CAS will be performed. This analysis is based on the documented observations of the authors, the study reports, protocols, lab reports and published publications. To additionally evaluate the scientific experience in an interdisciplinary research team, a literature analysis regarding scientific literature on trans- and inter-disciplinarity was performed. Own research and literature analyses were compared. Both the literature and the scientific experience in an interdisciplinary research team show that consensus finding is not always easy. It is, however, important to start trans- and interdisciplinary projects with a shared mental model and common goals, which include communication and leadership issues within the project teams, i.e. clear and unambiguous information about the individual responsibilities and objectives to attain. This is made necessary due to differing

  4. Calcium-regulation of mitochondrial respiration maintains ATP homeostasis and requires ARALAR/AGC1-malate aspartate shuttle in intact cortical neurons.

    PubMed

    Llorente-Folch, Irene; Rueda, Carlos B; Amigo, Ignacio; del Arco, Araceli; Saheki, Takeyori; Pardo, Beatriz; Satrústegui, Jorgina

    2013-08-28

    Neuronal respiration is controlled by ATP demand and Ca2+ but the roles played by each are unknown, as any Ca2+ signal also impacts on ATP demand. Ca2+ can control mitochondrial function through Ca2+-regulated mitochondrial carriers, the aspartate-glutamate and ATP-Mg/Pi carriers, ARALAR/AGC1 and SCaMC-3, respectively, or in the matrix after Ca2+ transport through the Ca2+ uniporter. We have studied the role of Ca2+ signaling in the regulation of mitochondrial respiration in intact mouse cortical neurons in basal conditions and in response to increased workload caused by increases in [Na+]cyt (veratridine, high-K+ depolarization) and/or [Ca2+]cyt (carbachol). Respiration in nonstimulated neurons on 2.5-5 mm glucose depends on ARALAR-malate aspartate shuttle (MAS), with a 46% drop in aralar KO neurons. All stimulation conditions induced increased OCR (oxygen consumption rate) in the presence of Ca2+, which was prevented by BAPTA-AM loading (to preserve the workload), or in Ca2+-free medium (which also lowers cell workload). SCaMC-3 limits respiration only in response to high workloads and robust Ca2+ signals. In every condition tested Ca2+ activation of ARALAR-MAS was required to fully stimulate coupled respiration by promoting pyruvate entry into mitochondria. In aralar KO neurons, respiration was stimulated by veratridine, but not by KCl or carbachol, indicating that the Ca2+ uniporter pathway played a role in the first, but not in the second condition, even though KCl caused an increase in [Ca2+]mit. The results suggest a requirement for ARALAR-MAS in priming pyruvate entry in mitochondria as a step needed to activate respiration by Ca2+ in response to moderate workloads.

  5. Making Technology Work for Your Students.

    ERIC Educational Resources Information Center

    Trosko, Nancy

    1997-01-01

    Discusses benefits of using laser disc technology in the elementary school classroom including increased student enthusiasm and subject relevance, efficient test preparation, and comprehensible materials for English-challenged students. Notes the importance of researching available resources and easing into use when integrating technology into the…

  6. Development and Substantiation of Parameters of Environmentally Friendly Technology for Filling the Vertical Mine Workings with Autoclaved Slag-Concrete

    NASA Astrophysics Data System (ADS)

    Uglyanitca, Andrey; Solonin, Kirill

    2017-11-01

    The environmentally friendly technology for filling the vertical mine workings with autoclaved slag-concrete, prefabricated on the surface of the mine is presented in the article; the optimal parameters of filling technology are proposed. The developed technology for filling the abandoned vertical mine workings allows ensuring the environmental safety of the territories adjacent to the abandoned mine, utilizing slag dumps and providing the possibility of shaft recovery, if necessary, with minimal labor and material costs.

  7. Social Media and Networking Technologies: An Analysis of Collaborative Work and Team Communication

    ERIC Educational Resources Information Center

    Okoro, Ephraim A.; Hausman, Angela; Washington, Melvin C.

    2012-01-01

    Digital communication increases students' learning outcomes in higher education. Web 2.0 technologies encourages students' active engagement, collaboration, and participation in class activities, facilitates group work, and encourages information sharing among students. Familiarity with organizational use and sharing in social networks aids…

  8. SUVmax/THKmax as a Biomarker for Distinguishing Advanced Gastric Carcinoma from Primary Gastric Lymphoma

    PubMed Central

    Fu, Liping; Li, Hongming; Wang, Hui; Xu, Baixuan; Fan, Yong; Tian, Jiahe

    2012-01-01

    Background Gastric carcinoma and primary gastric lymphoma (PGL) are the two most common malignancies in stomach. The purpose of this study was to screen and validate a biomarker of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) for distinguishing advanced gastric carcinoma (AGC) from PGL for clinical applications. Methodology/Principal Findings We reviewed PET/CT scans collected from January 2008 to April 2012 of 69 AGC and 38 PGL (14 low-grade mucosa-associated lymphoid tissue [MALT], 24 non-MALT aggressive non-Hodgkin lymphoma [ANHL]) with a focus on FDG intensity (maximum standardized uptake value [SUVmax]) of primary lesions and its CT-detected abnormalities, including maximal gastrointestinal wall thickness (THKmax) and mucosal ulcerations. Gastric FDG uptake was found in 69 (100%) patients with AGC and 36 (95%, 12 MALT vs. 24 ANHL)with PGL. The presence of CT-detected abnormalities of AGC and PGL were 97% (67/69) and 89% (12 MALT vs. 22 ANHL), respectively. After controlling for THKmax, SUVmax was higher with ANHL than AGC (17.10±8.08 vs. 9.65±5.24, p<0.05) and MALT (6.20±3.60, p<0.05). THKmax did not differ among MALT, ANHL and AGC. Mucosal ulceration was more common with AGC (n = 9) than PGL (n = 2),but the difference was not statistically significant (p>0.05). Cross-validation analysis showed that for distinguishing ANHL from AGC, the classifier with SUVmax as a feature achieved a correct classification rate of 81% with thresholds 13.40±1.12 and the classifier with SUVmax/THKmax as a feature achieved a correct classification rate of 83% with thresholds 7.51±0.63. Conclusions/Significance SUVmax/THKmax may be as a promising biomarker of FDG-PET/CT for distinguishing ANHL from AGC. Structural CT abnormalities alone may not be reliable but can help with PET assessment of gastric malignancies. 18F-FDG PET/CT have potential for distinguishing AGC from PGL at the individual level. PMID:23226547

  9. Two men with multiple disabilities carry out an assembly work activity with the support of a technology system.

    PubMed

    Lancioni, Giulio E; Singh, Nirbhay N; O'Reilly, Mark F; Green, Vanessa A; Oliva, Doretta; Campodonico, Francesca

    2013-10-01

    To assess whether two persons with multiple disabilities could learn a work activity (i.e., assembling trolley wheels) with the support of a technology system. After an initial baseline, the study compared the effects of intervention sessions relying on the technology system (which called the participants to the different workstations and provided feedback and final stimulation) with the effects of intervention sessions carried out without technology. The two types of intervention sessions were conducted according to an alternating treatments design. Eventually, only intervention sessions relying on the technology system were used. Both participants managed to assemble wheels independently during intervention sessions relying on the technology system while they failed during sessions without the system. Their performance was strengthened during the final part of the study, in which only sessions with the system occurred. Technology may be critical in helping persons with multiple disabilities manage multi-step work activities.

  10. Matching Automatic Gain Control Across Devices in Bimodal Cochlear Implant Users.

    PubMed

    Veugen, Lidwien C E; Chalupper, Josef; Snik, Ad F M; Opstal, A John van; Mens, Lucas H M

    2016-01-01

    The purpose of this study was to improve bimodal benefit in listeners using a cochlear implant (CI) and a hearing aid (HA) in contralateral ears, by matching the time constants and the number of compression channels of the automatic gain control (AGC) of the HA to the CI. Equivalent AGC was hypothesized to support a balanced loudness for dynamically changing signals like speech and improve bimodal benefit for speech understanding in quiet and with noise presented from the side(s) at 90 degree. Fifteen subjects participated in the study, all using the same Advanced Bionics Harmony CI processor and HA (Phonak Naida S IX UP). In a 3-visit crossover design with 4 weeks between sessions, performance was measured using a HA with a standard AGC (syllabic multichannel compression with 1 ms attack time and 50 ms release time) or an AGC that was adjusted to match that of the CI processor (dual AGC broadband compression, 3 and 240 msec attack time, 80 and 1500 msec release time). In all devices, the AGC was activated above the threshold of 63 dB SPL. The authors balanced loudness across the devices for soft and loud input sounds in 3 frequency bands (0 to 548, 548 to 1000, and >1000 Hz). Speech understanding was tested in free field in quiet and in noise for three spatial speaker configurations, with target speech always presented from the front. Single-talker noise was either presented from the CI side or the HA side, or uncorrelated stationary speech-weighted noise or single-talker noise was presented from both sides. Questionnaires were administered to assess differences in perception between the two bimodal fittings. Significant bimodal benefit over the CI alone was only found for the AGC-matched HA for the speech tests with single-talker noise. Compared with the standard HA, matched AGC characteristics significantly improved speech understanding in single-talker noise by 1.9 dB when noise was presented from the HA side. AGC matching increased bimodal benefit

  11. Who owns the Brazilian carbon?

    PubMed

    Freitas, Flavio L M; Englund, Oskar; Sparovek, Gerd; Berndes, Göran; Guidotti, Vinicius; Pinto, Luís F G; Mörtberg, Ulla

    2018-05-01

    Brazil is one of the major contributors to land-use change emissions, mostly driven by agricultural expansion for food, feed, and bioenergy feedstock. Policies to avoid deforestation related to private commitments, economic incentives, and other support schemes are expected to improve the effectiveness of current command and control mechanisms increasingly. However, until recently, land tenure was unknown for much of the Brazilian territory, which has undermined the governance of native vegetation and challenged support and incentive mechanisms for avoiding deforestation. We assess the total extent of public governance mechanisms protecting aboveground carbon (AGC) stocks. We constructed a land tenure dataset for the entire nation and modeled the effects and uncertainties of major land-use acts on protecting AGC stocks. Roughly 70% of the AGC stock in Brazil is estimated to be under legal protection, and an additional 20% is expected to be protected after areas in the Amazon with currently undesignated land undergo a tenure regularization. About 30% of the AGC stock is on private land, of which roughly two-thirds are protected. The Cerrado, Amazon, and Caatinga biomes hold about 40%, 30%, and 20% of the unprotected AGC, respectively. Effective conservation of protected and unprotected carbon will depend on successful implementation of the Forest Act, and regularization of land tenure in the Amazon. Policy development that prioritizes unprotected AGC stocks is warranted to promote conservation of native vegetation beyond the legal requirements. However, different biomes and land tenure structures may require different policy settings considering local and regional specifics. Finally, the fate of current AGC stocks relies upon effective implementation of command and control mechanisms, considering that unprotected AGC in native vegetation on private land only accounts for 6.5% of the total AGC stock. © 2017 John Wiley & Sons Ltd.

  12. Molecular targeted therapy for advanced gastric cancer.

    PubMed

    Kim, Jong Gwang

    2013-03-01

    Although medical treatment has been shown to improve quality of life and prolong survival, no significant progress has been made in the treatment of advanced gastric cancer (AGC) within the last two decades. Thus, the optimum standard first-line chemotherapy regimen for AGC remains debatable, and most responses to chemotherapy are partial and of short duration; the median survival is approximately 7 to 11 months, and survival at 2 years is exceptionally > 10%. Recently, remarkable progress in tumor biology has led to the development of new agents that target critical aspects of oncogenic pathways. For AGC, many molecular targeting agents have been evaluated in international randomized studies, and trastuzumab, an anti-HER-2 monoclonal antibody, has shown antitumor activity against HER-2-positive AGC. However, this benefit is limited to only ~20% of patients with AGC (patients with HER-2-positive AGC). Therefore, there remains a critical need for both the development of more effective agents and the identification of molecular predictive and prognostic markers to select those patients who will benefit most from specific chemotherapeutic regimens and targeted therapies.

  13. New Technologies Smart, or Harm Work-Family Boundaries Management? Gender Differences in Conflict and Enrichment Using the JD-R Theory

    PubMed Central

    Ghislieri, Chiara; Emanuel, Federica; Molino, Monica; Cortese, Claudio G.; Colombo, Lara

    2017-01-01

    Background: The relationship between technology-assisted supplemental work and well-being outcomes is a recent issue in scientific literature. Whether the use of technology for work purpose in off-work time may have a positive or negative impact on work-family balance remains an open question and the role of gender in this relationship is poorly understood. Aim: According to the JD-R theory, this study aimed to investigate the relationship between off-work hours technology assisted job demand (off-TAJD) and both work-family conflict (WFC) and work-family enrichment (WFE). Moreover, it considered two general job demands, workload and emotional dissonance, and one job resource, supervisory coaching. Method: The hypotheses were tested with a convenience sample of 671 workers. Data were collected with a self-report questionnaire and analyzed with SPSS 23 and through multi-group structural equation model (SEM) (Mplus 7). Results: The estimated SEM [Chi-square (510) = 1041.29; p < 0.01; CFI = 0.95; TLI = 0.95; RMSEA = 0.06 (0.05, 0.06); SRMR = 0.05. M = 319/F = 352] showed that off-TAJD was positively related to WFC in both subsamples; off-TAJD was positively related also to WFE only in the Male group. Workload was positively related to WFC in both Male and Female subsamples. Emotional dissonance was positively related to WFC in both subsamples and was negatively related to WFE. Supervisory coaching was strongly, positively related to WFE in both groups, and only in the Male subsample presented a low negative relationship with WFC. Conclusion: This study contributes to the literature on new challenges in work-life interface by analyzing the association between off-TAJD and WFC and Enrichment. Our findings suggest it is important to pay attention to gender differences in the study of the impact of supplemental work carried out during off-work hours using technology on the work-life interface. In fact, employee perception of Company demands of being available during off-work

  14. New Technologies Smart, or Harm Work-Family Boundaries Management? Gender Differences in Conflict and Enrichment Using the JD-R Theory.

    PubMed

    Ghislieri, Chiara; Emanuel, Federica; Molino, Monica; Cortese, Claudio G; Colombo, Lara

    2017-01-01

    Background: The relationship between technology-assisted supplemental work and well-being outcomes is a recent issue in scientific literature. Whether the use of technology for work purpose in off-work time may have a positive or negative impact on work-family balance remains an open question and the role of gender in this relationship is poorly understood. Aim: According to the JD-R theory, this study aimed to investigate the relationship between off-work hours technology assisted job demand (off-TAJD) and both work-family conflict (WFC) and work-family enrichment (WFE). Moreover, it considered two general job demands, workload and emotional dissonance, and one job resource, supervisory coaching. Method: The hypotheses were tested with a convenience sample of 671 workers. Data were collected with a self-report questionnaire and analyzed with SPSS 23 and through multi-group structural equation model (SEM) (Mplus 7). Results: The estimated SEM [Chi-square (510) = 1041.29; p < 0.01; CFI = 0.95; TLI = 0.95; RMSEA = 0.06 (0.05, 0.06); SRMR = 0.05. M = 319/F = 352] showed that off-TAJD was positively related to WFC in both subsamples; off-TAJD was positively related also to WFE only in the Male group. Workload was positively related to WFC in both Male and Female subsamples. Emotional dissonance was positively related to WFC in both subsamples and was negatively related to WFE. Supervisory coaching was strongly, positively related to WFE in both groups, and only in the Male subsample presented a low negative relationship with WFC. Conclusion: This study contributes to the literature on new challenges in work-life interface by analyzing the association between off-TAJD and WFC and Enrichment. Our findings suggest it is important to pay attention to gender differences in the study of the impact of supplemental work carried out during off-work hours using technology on the work-life interface. In fact, employee perception of Company demands of being available during off-work

  15. Using Technology To Improve Remote User Support: A Report from the "In Your Face" Working Committee.

    ERIC Educational Resources Information Center

    Schlabach, Marty; Callais, Donna; Davis, Phil; Kehoe, Bill; Trelease, Ben

    In July 1996, the Library Director of Cornell University's Mann Library formed a working committee to explore the technology solutions to providing a library presence with remote users. The committee began its explorations by brainstorming possible services that would utilize technology to bring the library closer to the remote user. After…

  16. 75 FR 24744 - Notice of Lodging of Consent Decree Under the Comprehensive Environmental Response, Compensation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... Decree in United States of America v. AGC Flat Glass North America, Inc., et al., Civil Action No. 1:10... County, West Virginia (the ``Site''). The Consent Decree obligates AGC Flat Glass North America, Inc. and... States of America v. AGC Flat Glass North America, Inc., et al., Civil Action No. 1:10-cv-00069-IMK, (N.D...

  17. Interventions aimed at improving the ability to use everyday technology in work after brain injury.

    PubMed

    Kassberg, Ann-Charlotte; Prellwitz, Maria; Malinowsky, Camilla; Larsson-Lund, Maria

    2016-01-01

    The aim of this study was to explore and describe how client-centred occupational therapy interventions may support and improve the ability to use everyday technology (ET) in work tasks in people with acquired brain injury (ABI). A qualitative, descriptive multiple-case study was designed, and occupation-based interventions were provided to three working-age participants with ABI. Multiple sources were used to collect data throughout the three intervention processes, including assessments, field notes, and interviews. The Canadian Occupational Performance Measure and the Management of Everyday Technology Assessment were administered before the interventions, after the interventions and at a follow-up session 2-3 months subsequent to the interventions. The three intervention processes initially consisted of similar actions, but subsequently the actions took on a different focus and intensity for each case. All of the goals in each of the three case processes were achieved, and both perceived and observed abilities to use ET in work tasks improved. Client-centred occupational therapy interventions might have the potential to improve the ability to use ET in work tasks in people with ABI.

  18. Technology's Impact on Faculty Life and Work.

    ERIC Educational Resources Information Center

    Baldwin, Roger G.

    1998-01-01

    Looks at the effects of advancing technology on academic life, using a simplified version of a scheme for examining diffusion of innovations. Attention is given to technology's impact on teaching, research and scholarship, and service and outreach functions, and on special challenges posed by technology, barriers to its use, and its implications…

  19. Center Director Bridges visits Disability Awareness and Action working Group Technology Fair

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Center Director Roy Bridges stops at the Stewart Eye Institute table at the Disability Awareness and Action Working Group (DAAWG) 1999 Technology Fair being held Oct. 20-21 at Kennedy Space Center. Behind Bridges is Sterling Walker, director of Engineering Development at KSC and chairman of DAAWG. At the near right are George and Marian Hall, who are with the Institute. At the left is Nancie Strott, a multi-media specialist with Dynacs and chairperson of the Fair. The Fair is highlighting vendors demonstrating mobility, hearing, vision and silent disability assistive technology. The purpose is to create an awareness of the types of technology currently available to assist people with various disabilities in the workplace. The theme is that of this year's National Disability Employment Awareness Month, 'Opening Doors to Ability.' Some of the vendors participating are Canine Companions for Independence, Goodwill Industries, Accessible Structures, Division of Blind Services, Space Coast Center for Independent Living, KSC Fitness Center and Delaware North Parks Services.

  20. Center Director Bridges visits Disability Awareness and Action working Group Technology Fair

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Center Director Roy Bridges stops to talk to one of the vendors at the Disability Awareness and Action Working Group (DAAWG) Technology Fair being held Oct. 20-21 at Kennedy Space Center. With him at the far left is Sterling Walker, director of Engineering Development at KSC and chairman of DAAWG, and Nancie Strott, a multi-media specialist with Dynacs and chairperson of the Fair; at the right is Carol Cavanaugh, with KSC Public Services. The Fair is highlighting vendors demonstrating mobility, hearing, vision and silent disability assistive technology. The purpose is to create an awareness of the types of technology currently available to assist people with various disabilities in the workplace. The theme is that of this year's National Disability Employment Awareness Month, 'Opening Doors to Ability.' Some of the vendors participating are Canine Companions for Independence, Goodwill Industries, Accessible Structures, Division of Blind Services, Space Coast Center for Independent Living, KSC Fitness Center and Delaware North Parks Services.

  1. Center Director Bridges visits Disability Awareness and Action working Group Technology Fair

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Center Director Roy Bridges stops to pet one of the dogs that serves with Canine Companions for Independence, a vendor displaying its capabilities at the Disability Awareness and Action Working Group (DAAWG) 1999 Technology Fair being held Oct. 20-21 at Kennedy Space Center. Standing at the right is Carol Cavanaugh, with KSC Public Services; behind Bridges is Nancie Strott (left), a multi-media specialist with Dynacs and chairperson of the Fair, and Sterling Walker (right), director of Engineering Development and chairman of DAAWG. The Fair is highlighting vendors demonstrating mobility, hearing, vision and silent disability assistive technology. The purpose is to create an awareness of the types of technology currently available to assist people with various disabilities in the workplace. The theme is that of this year's National Disability Employment Awareness Month, 'Opening Doors to Ability.' Some of the other vendors participating are Goodwill Industries, Accessible Structures, Division of Blind Services, Space Coast Center for Independent Living, KSC Fitness Center and Delaware North Parks Services.

  2. Learning What Works in Educational Technology with a Case Study of EDUSTAR. Policy Memo 2016-01

    ERIC Educational Resources Information Center

    Chatterji, Aaron K.; Jones, Benjamin F.

    2016-01-01

    Despite much fanfare, new technologies have yet to fundamentally advance student outcomes in K-12 schools or other educational settings. We believe that the system that supports the development and dissemination of educational technology tools is falling short. The key missing ingredient is rigorous evaluation. No one knows what works and for…

  3. New biocide guanidine-containing nanocomposites

    NASA Astrophysics Data System (ADS)

    Gorbunova, Marina; Lemkina, Larisa

    2014-08-01

    New water-soluble nanocomposites based on Ag and copolymers of 2,2-diallyl-1,1,3,3-tetraethylguanidiniumchloride with N-vinylpyrrolidone [poly(AGC-VP)] and vinylacetate [poly(AGC-VA)] have been developed. The average silver particle size ranged from 52 to 62 nm for poly(AGC-VA) and from 28 to 30 nm for poly(AGC-VP), with the corresponding UV-vis absorption peak position at 405-410 nm. The using of copolymers resulted in improvement in bactericide properties of composites. Following these results, the newly developed nanocomposite scaffold may be considered for new water-soluble medicines and biocides.

  4. Commutated automatic gain control system

    NASA Technical Reports Server (NTRS)

    Yost, S. R.

    1982-01-01

    A commutated automatic gain control (AGC) system was designed and built for a prototype Loran C receiver. The receiver uses a microcomputer to control a memory aided phase-locked loop (MAPLL). The microcomputer also controls the input/output, latitude/longitude conversion, and the recently added AGC system. The circuit designed for the AGC is described, and bench and flight test results are presented. The AGC circuit described actually samples starting at a point 40 microseconds after a zero crossing determined by the software lock pulse ultimately generated by a 30 microsecond delay and add network in the receiver front end envelope detector.

  5. Identification and Characterization of Ovarian Carcinoma Peptide Epitopes Recognized by Cytotoxic T Lymphocytes

    DTIC Science & Technology

    2007-11-01

    CCA CAG TGC CCC AGG TTA GAA CGG TCA GCA GAA TAG-2a 62 528 AGC GGC GGG CTG AAG GA GAG GGT AGG GTG GTC ATT GTG TCA TAG-2b 62 401 AGC GGC GGG CTG AAG...GGT AGG GTG GTC ATT GTG TCA TAG-2b 62 401 AGC GGC GGG CTG AAG GAC TC CAG CAC AAC AGG AAC ATT CAG TGG TAB-2c 62 536 AGC GGC GGG CTG AAG GA GGG GGA TTT...Makrigiannakis A, Gray H, Schlienger K, Liebman MN, Rubin SC, Coukos G (2003) Intratumoral T cells, recurrence, and survival in epithelial ovarian

  6. Art, Technology, and the Holy: Reflections on the Work of J. M. W. Turner

    ERIC Educational Resources Information Center

    Murray, Michael

    1974-01-01

    The following reflections focus on one of the late works by Turner, Rain, Steam, and Speed: The Great Western Railway (1844), and its possible bearing on the three-fold theme of art, technology, and the holy. (Author)

  7. Engaging with Employers in Work-Based Learning: A Foundation Degree in Applied Technology

    ERIC Educational Resources Information Center

    Benefer, Richard

    2007-01-01

    Purpose: This paper aims to describe the work of Staffordshire University in engaging with local employers and local further education colleges in the development of a Foundation Degree in Applied Technology. Design/methodology/approach: Following an outline of current government policy in employer engagement, the paper identifies--from the…

  8. Continuous positive airway pressure machines and the work of coordinating technologies at home.

    PubMed

    Moreira, Tiago

    2008-06-01

    Research on the use of health technology at home has consistently reported that it is underpinned by users' evaluations of the technology in relation to their illness trajectory, their social network, and the place where it is used. Recent studies have also revealed that the efficacy of health technologies depends upon users' work that is largely invisible to professionals, managers and designers. This paper draws on the most widely used therapy for the management of sleep apnoea, continuous positive airway pressure (CPAP), to show how users maintain workable relationships between it and other technological elements of the domestic environment. Qualitative analysis was performed of an archive of messages sent to a web-based support group for sleep disorders between 1994 and 2007. Users describe two related techniques: first, drawing on their embodied knowledge of using domestic technologies to imagine potential, alternative environments for CPAP; and second, using their body as an instrument to assess the ;fit' of each of the attempted arrangements. The interaction between these two techniques entails frequent shifts in users' understandings of their illness and those involved in its management. Strategies of implementation of health technologies at home should acknowledge and incorporate the embodied knowledge processes of users.

  9. Genetic analysis of ectopic growth suppression during planar growth of integuments mediated by the Arabidopsis AGC protein kinase UNICORN.

    PubMed

    Enugutti, Balaji; Schneitz, Kay

    2013-01-02

    The coordination of growth within a tissue layer is of critical importance for tissue morphogenesis. For example, cells within the epidermis undergo stereotypic cell divisions that are oriented along the plane of the layer (planar growth), thereby propagating the layered epidermal structure. Little is known about the developmental control that regulates such planar growth in plants. Recent evidence suggested that the Arabidopsis AGC VIII protein kinase UNICORN (UCN) maintains planar growth by suppressing the formation of ectopic multicellular protrusions in several floral tissues including integuments. In the current model UCN controls this process during integument development by directly interacting with the ABERRANT TESTA SHAPE (ATS) protein, a member of the KANADI (KAN) family of transcription factors, thereby repressing its activity. Here we report on the further characterization of the UCN mechanism. Phenotypic analysis of flowers of ucn-1 plants impaired in floral homeotic gene activity revealed that any of the four floral whorls could produce organs carrying ucn-1 protrusions. The ectopic outgrowths of ucn integuments did not accumulate detectable signals of the auxin and cytokinin reporters DR5rev::GFP and ARR5::GUS, respectively. Furthermore, wild-type and ucn-1 seedlings showed similarly strong callus formation upon in vitro culture on callus-inducing medium. We also show that ovules of ucn-1 plants carrying the dominant ats allele sk21-D exhibited more pronounced protrusion formation. Finally ovules of ucn-1 ett-1 double mutants and ucn-1 ett-1 arf4-1 triple mutants displayed an additive phenotype. These data deepen the molecular insight into the UCN-mediated control of planar growth during integument development. The presented evidence indicates that UCN downstream signaling does not involve the control of auxin or cytokinin homeostasis. The results also reveal that UCN interacts with ATS independently of an ATS/ETT complex required for integument

  10. Genetic analysis of ectopic growth suppression during planar growth of integuments mediated by the Arabidopsis AGC protein kinase UNICORN

    PubMed Central

    2013-01-01

    Background The coordination of growth within a tissue layer is of critical importance for tissue morphogenesis. For example, cells within the epidermis undergo stereotypic cell divisions that are oriented along the plane of the layer (planar growth), thereby propagating the layered epidermal structure. Little is known about the developmental control that regulates such planar growth in plants. Recent evidence suggested that the Arabidopsis AGC VIII protein kinase UNICORN (UCN) maintains planar growth by suppressing the formation of ectopic multicellular protrusions in several floral tissues including integuments. In the current model UCN controls this process during integument development by directly interacting with the ABERRANT TESTA SHAPE (ATS) protein, a member of the KANADI (KAN) family of transcription factors, thereby repressing its activity. Here we report on the further characterization of the UCN mechanism. Results Phenotypic analysis of flowers of ucn-1 plants impaired in floral homeotic gene activity revealed that any of the four floral whorls could produce organs carrying ucn-1 protrusions. The ectopic outgrowths of ucn integuments did not accumulate detectable signals of the auxin and cytokinin reporters DR5rev::GFP and ARR5::GUS, respectively. Furthermore, wild-type and ucn-1 seedlings showed similarly strong callus formation upon in vitro culture on callus-inducing medium. We also show that ovules of ucn-1 plants carrying the dominant ats allele sk21-D exhibited more pronounced protrusion formation. Finally ovules of ucn-1 ett-1 double mutants and ucn-1 ett-1 arf4-1 triple mutants displayed an additive phenotype. Conclusions These data deepen the molecular insight into the UCN-mediated control of planar growth during integument development. The presented evidence indicates that UCN downstream signaling does not involve the control of auxin or cytokinin homeostasis. The results also reveal that UCN interacts with ATS independently of an ATS

  11. Genome-wide analysis of DNA copy number alterations in early and advanced gastric cancers.

    PubMed

    Arakawa, Noriyuki; Sugai, Tamotsu; Habano, Wataru; Eizuka, Makoto; Sugimoto, Ryo; Akasaka, Risaburo; Toya, Yosuke; Yamamoto, Eiichiro; Koeda, Keisuke; Sasaki, Akira; Matsumoto, Takayuki; Suzuki, Hiromu

    2017-02-01

    To better understand progressive changes in gastric cancer (GC), early and advanced GCs (EGC and AGC, respectively) were examined for copy number alterations (CNAs). A crypt isolation method was used to isolate DNA from tumors and normal glands in 20 AGCs, and fresh tumor samples were obtained from 45 EGCs. We assessed CNAs for differentiated-type GCs using an Infinium HumanCytoSNP-12v2.1 BeadChip in EGCs and AGCs. The most frequent aberrations in EGC were gains at 8q23.3 (42.2%) and 8q23.2 (40%), and loss of heterozygosity (LOH) at 3p14.2 (24.2%), suggesting that these CNAs were involved in the development of EGC. On the other hand, the highest frequencies of gains in AGC were found at 8q24.21 (65%) and 8q24.3 (60%). The most frequent LOHs in AGC were at 11q24.3-25, 11q23.2-24.1, 11q14.1, and 12p11.21-13.33, whereas that in EGC was at 3p14.2. In addition, regions of copy-neutral LOHs in AGC were detected at 11q21, 11q13.3-14.3, 11q11, 11p13-15.3, 12q21.1, 12q12-13.3 and 5q33.3-35.1. Comparisons of gains in EGC and AGC showed significant differences at 12q22-q23.2, 12q21.33, 11p12, 11p14.1, 12q21.31-32.32, 3p12.3, 3p14.1, 10p15.1, 1q24.2 and 2q12.1. Copy neutral LOHs were significantly higher in AGC than in EGC at 14q32.11-32.33, 14q21.3, 14q11.2, 5q11.2, 5q 13.3, 14q21.1-23.2, 14q13.2-13.3, 5q12.1-12.3, 5q11.1, and 17p13.3. The total lengths of the CNAs were significantly greater in AGC than in EGC. We found that the pattern of CNAs in AGC was quite different from that in EGC. We suggest that increasing numbers of CNAs are associated with disease progression from EGC to AGC. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  12. Compelled to Be Connected: An Ethnographic Exploration of Organizational Culture, Work-Life Balance, and the Use of Mobile Workplace Technologies

    ERIC Educational Resources Information Center

    Thomas, Kristopher J.

    2013-01-01

    This study is an ethnographic exploration of organizational culture, work-life balance, and the use of information and communication technology ("ICT") in the work and home settings. The researcher was embedded for nine weeks within the Information Technology ("IT") department at the corporate headquarters of a mid-sized…

  13. Examining spectral properties of Landsat 8 OLI for predicting above-ground carbon of Labanan Forest, Berau

    NASA Astrophysics Data System (ADS)

    Suhardiman, A.; Tampubolon, B. A.; Sumaryono, M.

    2018-04-01

    Many studies revealed significant correlation between satellite image properties and forest data attributes such as stand volume, biomass or carbon stock. However, further study is still relevant due to advancement of remote sensing technology as well as improvement on methods of data analysis. In this study, the properties of three vegetation indices derived from Landsat 8 OLI were tested upon above-ground carbon stock data from 50 circular sample plots (30-meter radius) from ground survey in PT. Inhutani I forest concession in Labanan, Berau, East Kalimantan. Correlation analysis using Pearson method exhibited a promising results when the coefficient of correlation (r-value) was higher than 0.5. Further regression analysis was carried out to develop mathematical model describing the correlation between sample plots data and vegetation index image using various mathematical models.Power and exponential model were demonstrated a good result for all vegetation indices. In order to choose the most adequate mathematical model for predicting Above-ground Carbon (AGC), the Bayesian Information Criterion (BIC) was applied. The lowest BIC value (i.e. -376.41) shown by Transformed Vegetation Index (TVI) indicates this formula, AGC = 9.608*TVI21.54, is the best predictor of AGC of study area.

  14. A comprehensive guide of remediation technologies for oil contaminated soil - Present works and future directions.

    PubMed

    Lim, Mee Wei; Lau, Ee Von; Poh, Phaik Eong

    2016-08-15

    Oil spills result in negative impacts on the environment, economy and society. Due to tidal and waves actions, the oil spillage affects the shorelines by adhering to the soil, making it difficult for immediate cleaning of the soil. As shoreline clean-up is the most costly component of a response operation, there is a need for effective oil remediation technologies. This paper provides a review on the remediation technologies for soil contaminated with various types of oil, including diesel, crude oil, petroleum, lubricating oil, bitumen and bunker oil. The methods discussed include solvent extraction, bioremediation, phytoremediation, chemical oxidation, electrokinetic remediation, thermal technologies, ultrasonication, flotation and integrated remediation technologies. Each of these technologies was discussed, and associated with their advantages, disadvantages, advancements and future work in detail. Nonetheless, it is important to note that no single remediation technology is considered the best solution for the remediation of oil contaminated soil. This review provides a comprehensive literature on the various remediation technologies studied in the removal of different oil types from soil. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Will Life Be Worth Living in a World Without Work? Technological Unemployment and the Meaning of Life.

    PubMed

    Danaher, John

    2017-02-01

    Suppose we are about to enter an era of increasing technological unemployment. What implications does this have for society? Two distinct ethical/social issues would seem to arise. The first is one of distributive justice: how will the (presumed) efficiency gains from automated labour be distributed through society? The second is one of personal fulfillment and meaning: if people no longer have to work, what will they do with their lives? In this article, I set aside the first issue and focus on the second. In doing so, I make three arguments. First, I argue that there are good reasons to embrace non-work and that these reasons become more compelling in an era of technological unemployment. Second, I argue that the technological advances that make widespread technological unemployment possible could still threaten or undermine human flourishing and meaning, especially if (as is to be expected) they do not remain confined to the economic sphere. And third, I argue that this threat could be contained if we adopt an integrative approach to our relationship with technology. In advancing these arguments, I draw on three distinct literatures: (1) the literature on technological unemployment and workplace automation; (2) the antiwork critique-which I argue gives reasons to embrace technological unemployment; and (3) the philosophical debate about the conditions for meaning in life-which I argue gives reasons for concern.

  16. Combined effect of pulse density and grid cell size on predicting and mapping aboveground carbon in fast‑growing Eucalyptus forest plantation using airborne LiDAR data

    Treesearch

    Carlos Alberto Silva; Andrew Thomas Hudak; Carine Klauberg; Lee Alexandre Vierling; Carlos Gonzalez‑Benecke; Samuel de Padua Chaves Carvalho; Luiz Carlos Estraviz Rodriguez; Adrian Cardil

    2017-01-01

    LiDAR measurements can be used to predict and map AGC across variable-age Eucalyptus plantations with adequate levels of precision and accuracy using 5 pulses m− 2 and a grid cell size of 5 m. The promising results for AGC modeling in this study will allow for greater confidence in comparing AGC estimates with varying LiDAR sampling densities for Eucalyptus plantations...

  17. Women@Work: Listening to Gendered Relations of Power in Teachers' Talk about New Technologies.

    ERIC Educational Resources Information Center

    Jenson, Jennifer; Rose, Chloe Brushwood

    2003-01-01

    Examines teachers' working identities, highlighting gender inequities among teachers, within school systems, and in society, especially in relation to computers. Highlights tensions central to teaching in relation to new technologies, emphasizing gender inequities that structure understandings of teaching. Documents how, for the teachers studied,…

  18. Emerging Issues in Science and Technology, 1982. A Compendium of Working Papers for the National Science Foundation.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC.

    Presented are nine working papers prepared for the National Science Foundation as one means of assisting the Office of Science and Technology Policy in preparing the administration's "Annual Science and Technology Report to the Congress, 1982." The papers explore aspects of three broad themes central to the administration's science and…

  19. Return to work in people with acquired brain injury: association with observed ability to use everyday technology.

    PubMed

    Larsson-Lund, Maria; Kottorp, Anders; Malinowsky, Camilla

    2017-07-01

    The aim of this study was to explore how the observed ability to use everyday technology (ET), intrapersonal capacities and environmental characteristics related to ET use contributes to the likelihood of return to work in people with ABI. The aim was also to explore whether these variables added to the likelihood of return to work to earlier defined significant variables in the group: age, perceived ADL ability and perceived ability in ET use. A cross-sectional study. The Management of Everyday Technology Assessment (META), the short version of the Everyday Technology Use Questionnaire (S-ETUQ) and a revised version of the ADL taxonomy were used to evaluate 74 people with ABI. Individual ability measures from all assessments were generated by Rasch analyses and used for additional statistical analysis. The univariate analyses showed that the observed ability to use ET, as well as intrapersonal capacities and environmental characteristics related to ET use were all significantly associated with returning to work. In the multivariate analyses, none of these associations remained. The explanatory precision of return to work in people with ABI increased minimally by adding the observed ability to use ET and the variables related to ET use when age, perceived ability in ET use and ADL had been taken in account.

  20. Active Power Control of Wind Turbines for Ancillary Services: A Comparison of Pitch and Torque Control Methodologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aho, Jacob; Fleming, Paul; Pao, Lucy Y.

    As wind energy generation becomes more prevalent in some regions, there is increased demand for wind power plants to provide ancillary services, which are essential for grid reliability. This paper compares two different wind turbine control methodologies to provide active power control (APC) ancillary services, which include derating or curtailing power generation, providing automatic generation control (AGC), and providing primary frequency control (PFC). The torque APC controller provides all power control through the power electronics whereas the pitch APC controller uses the blade pitch actuators as the primary means of power control. These controllers are simulated under various wind conditionsmore » with different derating set points and AGC participation levels. The metrics used to compare their performance are the damage equivalent loads (DELs) induced on the structural components and AGC performance metrics, which are used to determine the payments for AGC services by system operators in the United States. The simulation results show that derating the turbine reduces structural loads for both control methods, with the APC pitch control providing larger reductions in DELs, lower AGC performance scores, and higher root-mean-square pitch rates. Providing AGC increases the structural loads when compared to only derating the turbine, but even the AGC DELs are generally lower than those of the baseline control system. The torque APC control methodology also allows for more sustained PFC responses under certain derating conditions.« less

  1. Risk of invasive cervical cancer after atypical glandular cells in cervical screening: nationwide cohort study.

    PubMed

    Wang, Jiangrong; Andrae, Bengt; Sundström, Karin; Ström, Peter; Ploner, Alexander; Elfström, K Miriam; Arnheim-Dahlström, Lisen; Dillner, Joakim; Sparén, Pär

    2016-02-11

    To investigate the risks of invasive cervical cancer after detection of atypical glandular cells (AGC) during cervical screening. Nationwide population based cohort study. Cancer and population registries in Sweden. 3,054,328 women living in Sweden at any time between 1 January 1980 and 1 July 2011 who had any record of cervical cytological testing at ages 23-59. Of these, 2,899,968 women had normal cytology results at the first screening record. The first recorded abnormal result was atypical glandular cells (AGC) in 14 625, high grade squamous intraepithelial lesion (HSIL) in 65 633, and low grade squamous intraepithelial lesions (LSIL) in 244 168. Cumulative incidence of invasive cervical cancer over 15.5 years; proportion of invasive cervical cancer within six months of abnormality (prevalence); crude incidence rates for invasive cervical cancer over 0.5-15.5 years of follow-up; incidence rate ratios compared with women with normal cytology, estimated with Poisson regression adjusted for age and stratified by histopathology of cancer; distribution of clinical assessment within six months after the abnormality. The prevalence of cervical cancer was 1.4% for women with AGC, which was lower than for women with HSIL (2.5%) but higher than for women with LSIL (0.2%); adenocarcinoma accounted for 73.2% of the prevalent cases associated with AGC. The incidence rate of invasive cervical cancer after AGC was significantly higher than for women with normal results on cytology for up to 15.5 years and higher than HSIL and LSIL for up to 6.5 years. The incidence rate of adenocarcinoma was 61 times higher than for women with normal results on cytology in the first screening round after AGC, and remained nine times higher for up to 15.5 years. Incidence and prevalence of invasive cervical cancer was highest when AGC was found at ages 30-39. Only 54% of women with AGC underwent histology assessment within six months, much less than after HSIL (86%). Among women with histology

  2. Risk of invasive cervical cancer after atypical glandular cells in cervical screening: nationwide cohort study

    PubMed Central

    Andrae, Bengt; Sundström, Karin; Ström, Peter; Ploner, Alexander; Elfström, K Miriam; Arnheim-Dahlström, Lisen; Dillner, Joakim; Sparén, Pär

    2016-01-01

    Objectives To investigate the risks of invasive cervical cancer after detection of atypical glandular cells (AGC) during cervical screening. Design Nationwide population based cohort study. Setting Cancer and population registries in Sweden. Participants 3 054 328 women living in Sweden at any time between 1 January 1980 and 1 July 2011 who had any record of cervical cytological testing at ages 23-59. Of these, 2 899 968 women had normal cytology results at the first screening record. The first recorded abnormal result was atypical glandular cells (AGC) in 14 625, high grade squamous intraepithelial lesion (HSIL) in 65 633, and low grade squamous intraepithelial lesions (LSIL) in 244 168. Main outcome measures Cumulative incidence of invasive cervical cancer over 15.5 years; proportion of invasive cervical cancer within six months of abnormality (prevalence); crude incidence rates for invasive cervical cancer over 0.5-15.5 years of follow-up; incidence rate ratios compared with women with normal cytology, estimated with Poisson regression adjusted for age and stratified by histopathology of cancer; distribution of clinical assessment within six months after the abnormality. Results The prevalence of cervical cancer was 1.4% for women with AGC, which was lower than for women with HSIL (2.5%) but higher than for women with LSIL (0.2%); adenocarcinoma accounted for 73.2% of the prevalent cases associated with AGC. The incidence rate of invasive cervical cancer after AGC was significantly higher than for women with normal results on cytology for up to 15.5 years and higher than HSIL and LSIL for up to 6.5 years. The incidence rate of adenocarcinoma was 61 times higher than for women with normal results on cytology in the first screening round after AGC, and remained nine times higher for up to 15.5 years. Incidence and prevalence of invasive cervical cancer was highest when AGC was found at ages 30-39. Only 54% of women with AGC underwent histology assessment

  3. WORK ETHICS, ORGANIZATIONAL ALIENATION AND JUSTICE AMONG HEALTH INFORMATION TECHNOLOGY MANAGERS.

    PubMed

    Zadeh, Jamileh Mahdi; Kahouei, Mehdi; Cheshmenour, Omran; Sangestani, Sajjad

    2016-06-01

    Failure to comply with work ethics by employees working in Health Information Technology (HIT) Departments and their negative attitudes about organizational justice may have an adverse impact on patient satisfaction, quality of care, collecting health statistics, reimbursement, and management and planning at all levels of health care; it can also lead to unbearable damages to the health information system in the country. As so far there has been no research on HIT managers to assess the moral and ethical aspects of works and their relationship with organizational alienation and justice, this study aimed to evaluate the relationship between work ethics and organizational justice and alienation among the HIT managers. This study was performed in affiliated hospitals of Semnan University of medical sciences in Semnan, Iran, in 2015. In this study, a census method was used. The data collection tool was a researcher made questionnaire. There was a negative and significant relationship between work ethic and organizational alienation (B= - 0.217, P<0.001), and there was also a positive and significant relationship between work ethic and organizational justice (B= 0.580, P<0.001). There were negative and significant relationships among between education level and work ethic (B= - 0.215, P=0.034) and organizational justice (B=- 0.147, P=0.047). The results of this study showed that the managers' attitude toward justice and equality in the organization can affect their organizational commitment and loyalty and thus have a significant impact on the work ethics in the work environment. On the other hand, with increasing the education level of the managers, they will have higher expectation of the justice in the organization, and they feel that the justice is not observed in the organization.

  4. WORK ETHICS, ORGANIZATIONAL ALIENATION AND JUSTICE AMONG HEALTH INFORMATION TECHNOLOGY MANAGERS

    PubMed Central

    Zadeh, Jamileh Mahdi; Kahouei, Mehdi; Cheshmenour, Omran; Sangestani, Sajjad

    2016-01-01

    Introduction: Failure to comply with work ethics by employees working in Health Information Technology (HIT) Departments and their negative attitudes about organizational justice may have an adverse impact on patient satisfaction, quality of care, collecting health statistics, reimbursement, and management and planning at all levels of health care; it can also lead to unbearable damages to the health information system in the country. As so far there has been no research on HIT managers to assess the moral and ethical aspects of works and their relationship with organizational alienation and justice, this study aimed to evaluate the relationship between work ethics and organizational justice and alienation among the HIT managers. Methods: This study was performed in affiliated hospitals of Semnan University of medical sciences in Semnan, Iran, in 2015. In this study, a census method was used. The data collection tool was a researcher made questionnaire. Results: There was a negative and significant relationship between work ethic and organizational alienation (B= - 0.217, P<0.001), and there was also a positive and significant relationship between work ethic and organizational justice (B= 0.580, P<0.001). There were negative and significant relationships among between education level and work ethic (B= - 0.215, P=0.034) and organizational justice (B=- 0.147, P=0.047). Conclusion: The results of this study showed that the managers’ attitude toward justice and equality in the organization can affect their organizational commitment and loyalty and thus have a significant impact on the work ethics in the work environment. On the other hand, with increasing the education level of the managers, they will have higher expectation of the justice in the organization, and they feel that the justice is not observed in the organization. PMID:27482167

  5. Emerging Issues in Science and Technology, 1981. A Compendium of Working Papers for the National Science Foundation.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC.

    The eight working papers presented in this compendium were prepared for the National Science Foundation (NSF) as one means to assist the Office of Science and Technology Policy with preparation of the Administration's Annual Science and Technology Report to the Congress, 1981. They focus on specific aspects of three central themes directly related…

  6. Bridging the Hemispheres through the Use of Technology: International Collaboration in Social Work Training

    ERIC Educational Resources Information Center

    Rautenbach, John Victor; Black-Hughes, Christine

    2012-01-01

    The social work programs of the University of Fort Hare, East London, South Africa, and Minnesota State University, Mankato, United States, began using various technologies in 2007 to facilitate interaction. This project included conducting practicum supervision and seminars via videoconferencing (using Breeze, Adobe Connect, and Skype) and…

  7. Clinical significance of atypical glandular cells in Pap tests: An analysis of more than 3000 cases at a large academic women's center.

    PubMed

    Pradhan, Dinesh; Li, Zaibo; Ocque, Rebecca; Patadji, Stell; Zhao, Chengquan

    2016-08-01

    The interpretation of atypical glandular cells (AGC) in Papanicolaou (Pap) tests and screening for glandular neoplasia remain challenging. Pap tests with an AGC interpretation from January 2008 to December 2013 were retrieved from a pathology database, and cases with histologic follow-up within 1 year were included in the study. There were 589,830 Pap tests during the study period, and 3709 cases (0.6%) were reported as AGC, which included the following: AGC, not otherwise specified (52.0%); atypical endocervical cells (28.0%); and other categories. There were 3007 cases (81.1%) with histologic follow-up results within 1 year. Cervical intraepithelial neoplasia 2/3 (CIN2/3), cervical adenocarcinoma in situ (AIS)/adenocarcinoma, and endometrial carcinoma were identified in 5.6%, 1.9%, and 5.5% of cases, respectively. Glandular neoplasia was more likely to be identified in cases with pure AGC subcategories than cases with AGC and squamous abnormalities. Endometrial neoplasia was more likely to be identified in cases with atypical endometrial cells than other categories. Overall, the most common severe abnormality on histologic follow-up was CIN2/3. Although CIN2/3 was the most common severe lesion in patients younger than 30 years (10.0%) and in patients aged 30 to 49 years (6.4%), endometrial carcinoma was the most common lesion in women who were 50 years old or older (13.7%). Endocervical glandular lesions (AIS and adenocarcinoma) occurred in only 1.9% of women. AGC subtypes and ages significantly affect histological follow-up results; 90.5% of cases with carcinoma on histologic follow-up were either endometrial or metastatic carcinoma. This study supports the recommendation that women with AGC Pap test results should be followed up with both endocervical and endometrial sampling. Cancer Cytopathol 2016;124:589-95. © 2016 American Cancer Society. © 2016 American Cancer Society.

  8. A fast Monte Carlo EM algorithm for estimation in latent class model analysis with an application to assess diagnostic accuracy for cervical neoplasia in women with AGC

    PubMed Central

    Kang, Le; Carter, Randy; Darcy, Kathleen; Kauderer, James; Liao, Shu-Yuan

    2013-01-01

    In this article we use a latent class model (LCM) with prevalence modeled as a function of covariates to assess diagnostic test accuracy in situations where the true disease status is not observed, but observations on three or more conditionally independent diagnostic tests are available. A fast Monte Carlo EM (MCEM) algorithm with binary (disease) diagnostic data is implemented to estimate parameters of interest; namely, sensitivity, specificity, and prevalence of the disease as a function of covariates. To obtain standard errors for confidence interval construction of estimated parameters, the missing information principle is applied to adjust information matrix estimates. We compare the adjusted information matrix based standard error estimates with the bootstrap standard error estimates both obtained using the fast MCEM algorithm through an extensive Monte Carlo study. Simulation demonstrates that the adjusted information matrix approach estimates the standard error similarly with the bootstrap methods under certain scenarios. The bootstrap percentile intervals have satisfactory coverage probabilities. We then apply the LCM analysis to a real data set of 122 subjects from a Gynecologic Oncology Group (GOG) study of significant cervical lesion (S-CL) diagnosis in women with atypical glandular cells of undetermined significance (AGC) to compare the diagnostic accuracy of a histology-based evaluation, a CA-IX biomarker-based test and a human papillomavirus (HPV) DNA test. PMID:24163493

  9. Roles of AGCVIII Kinases in the Hypocotyl Phototropism of Arabidopsis Seedlings.

    PubMed

    Haga, Ken; Frank, Lena; Kimura, Taro; Schwechheimer, Claus; Sakai, Tatsuya

    2018-05-01

    Regulation of protein function by phosphorylation and dephosphorylation is an important mechanism in many cellular events. The phototropin blue-light photoreceptors, plant-specific AGCVIII kinases, are essential for phototropic responses. Members of the D6 PROTEIN KINASE (D6PK) family, representing a subfamily of the AGCVIII kinases, also contribute to phototropic responses, suggesting that possibly further AGCVIII kinases may potentially control phototropism. The present study investigates the functional roles of Arabidopsis (Arabidopsis thaliana) AGCVIII kinases in hypocotyl phototropism. We demonstrate that D6PK family kinases are not only required for the second but also for the first positive phototropism. In addition, we find that a previously uncharacterized AGCVIII protein, AGC1-12, is involved in the first positive phototropism and gravitropism. AGC1-12 phosphorylates serine residues in the cytoplasmic loop of PIN-FORMED 1 (PIN1) and shares phosphosite preferences with D6PK. Our work strongly suggests that the D6PK family and AGC1-12 are critical components for both hypocotyl phototropism and gravitropism, and that these kinases control tropic responses mainly through regulation of PIN-mediated auxin transport by protein phosphorylation.

  10. Pre-Service Teachers' Learning Styles and Preferences towards Instructional Technology Activities and Collaborative Works

    ERIC Educational Resources Information Center

    Yusop, Farrah Dina; Sumari, Melati

    2015-01-01

    The main purpose of this exploratory study was to investigate pre-service teachers' learning styles and their preferences with respect to 15 technology-based instructional activities and collaborative work tasks. Felder and Silverman's online Index of Learning Style (ILS) and a questionnaire were used to measure students' learning styles and…

  11. Issues Involved in Attempting to Develop Independent Learning in Pupils Working on Technological Projects

    ERIC Educational Resources Information Center

    Barak, Moshe

    2004-01-01

    This research addresses the impact of technological projects at high school on pupils' learning. The participants were sixty low-mid achieving pupils who worked for one year on final projects for matriculation exams. Data were collected through observations of laboratory lessons, interviews with pupils and teachers, and analysis of pupils'…

  12. Peroxiredoxins: A Model for a Self-Assembling Nanoscale System

    DTIC Science & Technology

    2014-08-24

    specific primers was: Forward: 5’ – GGC AGC GGC GCG ATG CCC GGC ATG GAA – 3’ Reverse: 5’ – GAA AGC TGG GTG CTA CTC CCC CCT TGC CT – 3’ The bold...8217 Reverse: 5’ – GGGG AC CAC TTT GTA CAA GAA AGC TGG GTG – 3’ The bold section introduces the attB sites to the linear fragment produced by reaction 1

  13. Technology and the Organisation of Work. EEE701 Adults Learning: The Changing Workplace B.

    ERIC Educational Resources Information Center

    Littler, Craig R.

    This publication is part of the study materials for the distance education course, Adults Learning: The Changing Workplace B, in the Open Campus Program at Deakin University. The first part of the document analyzes the relationship between technology, skill, and work within the context of the debates concerning deskilling and managerial control…

  14. Technology for Work, Home, and Leisure. Tech Use Guide: Using Computer Technology.

    ERIC Educational Resources Information Center

    Williams, John M.

    This guide provides a brief introduction to several types of technological devices useful to individuals with disabilities and illustrates how some individuals are applying technology in the workplace and at home. Devices described include communication aids, low-vision products, voice-activated systems, environmental controls, and aids for…

  15. A Comparison of the Irradiation Creep Behavior of Several Graphites

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burchell, Timothy D; Windes, Will

    2016-01-01

    Graphite creep strain data from the irradiation creep capsule Advanced Graphite Creep-1 (AGC-1) are reported. This capsule was the first (prototype) of a series of five or six capsules planned as part of the AGC experiment, which was designed to fully characterize the effects of neutron irradiation and the radiation creep behavior of current nuclear graphite. The creep strain data and analysis are reported for the six graphite grades incorporated in the capsule. The AGC-1 capsule was irradiated in the Advanced Test Reactor at Idaho National Laboratory (INL) at approximately 700 C and to a peak dose of 7 dpamore » (displacements per atom). The specimen s final dose, temperature, and stress conditions have been reported by INL and were used during this analysis. The derived creep coefficients (K) were calculated for each grade and were found to compare well to literature data for the creep coefficient, even under the wide range of AGC-1 specimen temperatures. Comparisons were made between AGC-1 data and historical grade data for creep coefficients.« less

  16. SDR input power estimation algorithms

    NASA Astrophysics Data System (ADS)

    Briones, J. C.; Nappier, J. M.

    The General Dynamics (GD) S-Band software defined radio (SDR) in the Space Communications and Navigation (SCAN) Testbed on the International Space Station (ISS) provides experimenters an opportunity to develop and demonstrate experimental waveforms in space. The SDR has an analog and a digital automatic gain control (AGC) and the response of the AGCs to changes in SDR input power and temperature was characterized prior to the launch and installation of the SCAN Testbed on the ISS. The AGCs were used to estimate the SDR input power and SNR of the received signal and the characterization results showed a nonlinear response to SDR input power and temperature. In order to estimate the SDR input from the AGCs, three algorithms were developed and implemented on the ground software of the SCAN Testbed. The algorithms include a linear straight line estimator, which used the digital AGC and the temperature to estimate the SDR input power over a narrower section of the SDR input power range. There is a linear adaptive filter algorithm that uses both AGCs and the temperature to estimate the SDR input power over a wide input power range. Finally, an algorithm that uses neural networks was designed to estimate the input power over a wide range. This paper describes the algorithms in detail and their associated performance in estimating the SDR input power.

  17. SDR Input Power Estimation Algorithms

    NASA Technical Reports Server (NTRS)

    Nappier, Jennifer M.; Briones, Janette C.

    2013-01-01

    The General Dynamics (GD) S-Band software defined radio (SDR) in the Space Communications and Navigation (SCAN) Testbed on the International Space Station (ISS) provides experimenters an opportunity to develop and demonstrate experimental waveforms in space. The SDR has an analog and a digital automatic gain control (AGC) and the response of the AGCs to changes in SDR input power and temperature was characterized prior to the launch and installation of the SCAN Testbed on the ISS. The AGCs were used to estimate the SDR input power and SNR of the received signal and the characterization results showed a nonlinear response to SDR input power and temperature. In order to estimate the SDR input from the AGCs, three algorithms were developed and implemented on the ground software of the SCAN Testbed. The algorithms include a linear straight line estimator, which used the digital AGC and the temperature to estimate the SDR input power over a narrower section of the SDR input power range. There is a linear adaptive filter algorithm that uses both AGCs and the temperature to estimate the SDR input power over a wide input power range. Finally, an algorithm that uses neural networks was designed to estimate the input power over a wide range. This paper describes the algorithms in detail and their associated performance in estimating the SDR input power.

  18. Defect scanning technology in the works

    Treesearch

    Philip A. Araman; R. Conners

    1994-01-01

    This article describes the defect scanning technology being developed by Virginia Tech and U.S. Forest Service scientists in Blacksburg, Virginia to scan full sized hardwood lumber at industrial speeds.

  19. Aboveground carbon sequestration in dry temperate forests varies with climate not fire regime.

    PubMed

    Gordon, Christopher E; Bendall, Eli R; Stares, Mitchell G; Collins, Luke; Bradstock, Ross A

    2018-06-01

    The storage of carbon in plant tissues and debris has been proposed as a method to offset anthropogenic increases in atmospheric [CO 2 ]. Temperate forests represent significant above-ground carbon (AGC) "sinks" because their relatively fast growth and slow decay rates optimise carbon assimilation. Fire is a common disturbance event in temperate forests globally that should strongly influence AGC because: discrete fires consume above-ground biomass releasing carbon to the atmosphere, and the long-term application of different fire-regimes select for specific plant communities that sequester carbon at different rates. We investigated the latter process by quantifying AGC storage at 104 sites in the Sydney Basin Bioregion, Australia, relative to differences in components of the fire regime: frequency, severity and interfire interval. To predict the potential impacts of future climate change on fire/AGC interactions, we stratified our field sites across gradients of mean annual temperature and precipitation and quantified within- and between-factor interactions between the fire and climate variables. In agreement with previous studies, large trees were the primary AGC sink, accounting for ~70% of carbon at sites. Generalised additive models showed that mean annual temperature was the strongest predictor of AGC storage, with a 54% near-linear decrease predicted across the 6.1°C temperature range experienced at sites. Mean annual precipitation, fire frequency, fire severity and interfire interval were consistently poor predictors of total above-ground storage, although there were some significant relationships with component stocks. Our results show resilience of AGC to frequent and severe wildfire and suggest temperature mediated decreases in forest carbon storage under future climate change predictions. © 2018 John Wiley & Sons Ltd.

  20. Native American Women Leaders' Use of Information and Communication Technologies (ICTs) for Work-Life Balance (WLB) and Capacity Building

    ERIC Educational Resources Information Center

    Jensen, Crystal C.

    2013-01-01

    Native American women's leadership, information communication technologies (ICTs), work-life balance (WLB) and human capacity building (HCB) are grounded in social justice issues due to their long history of overall cultural decimation, inequitable access to technology, monetary resources, and social power (agency), and influence. Currently, there…

  1. Creating technological boundaries to protect bedtime: examining work-home boundary management, psychological detachment and sleep.

    PubMed

    Barber, Larissa K; Jenkins, Jade S

    2014-08-01

    This study examined the mechanism by which information and communication technology (ICT) use at home for work purposes may affect sleep. In this investigation, data from 315 employees were used to examine the indirect effect of ICT use at home on sleep outcomes through psychological detachment, and how boundary creation may moderate this effect. Results revealed the indirect effect of increased work-home boundary crossing on sleep (quantity, quality and consistency) through psychological detachment occurred only among individuals with low boundaries around ICT use and not among those with high boundaries. These results suggest that creating boundaries around work-relevant ICT use while at home is beneficial to sleep as a recovery process through being able to psychologically disengage from work. Copyright © 2013 John Wiley & Sons, Ltd.

  2. Michigan State University Extension Educators' Perceptions of the Use of Digital Technology in Their Work

    ERIC Educational Resources Information Center

    Wells, Elizabeth Chase

    2009-01-01

    This research study examined Michigan State University Extension educators' perceptions of the use of digital technology in their work. It used a mixed method of research which included a mailed survey and interviews of selected respondents. A census survey using Dillman's Total Design method was sent to 290 field staff of Michigan State…

  3. Open path measurements of carbon dioxide and water vapor under foggy conditions - technical problems, approaches and effects on flux measurements and budget calculations

    NASA Astrophysics Data System (ADS)

    El-Madany, T.; Griessbaum, F.; Maneke, F.; Chu, H.-S.; Wu, C.-C.; Chang, S. C.; Hsia, Y.-J.; Juang, J.-Y.; Klemm, O.

    2010-07-01

    To estimate carbon dioxide or water vapor fluxes with the Eddy Covariance method high quality data sets are necessary. Under foggy conditions this is challenging, because open path measurements are influenced by the water droplets that cross the measurement path as well as deposit on the windows of the optical path. For the LI-7500 the deposition of droplets on the window results in an intensity reduction of the infrared beam. To keep the strength of the infrared beam under these conditions, the energy is increased. A measure for the increased energy is given by the AGC value (Automatic Gain Control). Up to a AGC threshold value of 70 % the data from the LI-7500 is assumed to be of good quality (personal communication with LICOR). Due to fog deposition on the windows, the AGC value rises above 70 % and stays there until the fog disappears and the water on the windows evaporates. To gain better data quality during foggy conditions, a blower system was developed that blows the deposited water droplets off the window. The system is triggered if the AGC value rises above 70 %. Then a pneumatic jack will lift the blower system towards the LI-7500 and the water-droplets get blown off with compressed air. After the AGC value drops below 70 %, the pneumatic jack will move back to the idle position. Using this technique showed that not only the fog droplets on the window causing significant problems to the measurement, but also the fog droplets inside the measurement path. Under conditions of very dense fog the measured values of carbon dioxide can get unrealistically high, and for water vapor, negative values can be observed even if the AGC value is below 70 %. The negative values can be explained by the scatter of the infrared beam on the fog droplets. It is assumed, that different types of fog droplet spectra are causing the various error patterns observed. For high quality flux measurements, not only the AGC threshold value of 70 % is important, but also the fluctuation

  4. Posture variation among office workers when using different information and communication technologies at work and away from work.

    PubMed

    Ciccarelli, Marina; Straker, Leon; Mathiassen, Svend Erik; Pollock, Clare

    2014-01-01

    Office workers perform tasks using different information and communication technologies (ICT) involving various postures. Adequate variation in postures and muscle activity is generally believed to protect against musculoskeletal complaints, but insufficient information exists regarding the effect on postural variation of using different ICT. Thus, this study among office workers aimed to determine and compare postures and postural variation associated with using distinct types of ICT. Upper arm, head and trunk postures of 24 office workers were measured with the Physiometer over a whole day in their natural work and away-from-work environments. Postural variation was quantified using two indices: APDF(90-10) and EVA(sd). Various ICT had different postural means and variation. Paper-based tasks had more non-neutral, yet also more variable postures. Electronics-based tasks had more neutral postures, with less postural variability. Tasks simultaneously using paper- and electronics-based ICT had least neutral and least variable postures. Tasks without ICT usually had the most posture variability. Interspersing tasks involving different ICT could increase overall exposure variation among office workers and may thus contribute to musculoskeletal risk reduction.

  5. Slc25a12 disruption alters myelination and neurofilaments: a model for a hypomyelination syndrome and childhood neurodevelopmental disorders.

    PubMed

    Sakurai, Takeshi; Ramoz, Nicolas; Barreto, Marta; Gazdoiu, Mihaela; Takahashi, Nagahide; Gertner, Michael; Dorr, Nathan; Gama Sosa, Miguel A; De Gasperi, Rita; Perez, Gissel; Schmeidler, James; Mitropoulou, Vivian; Le, H Carl; Lupu, Mihaela; Hof, Patrick R; Elder, Gregory A; Buxbaum, Joseph D

    2010-05-01

    SLC25A12, a susceptibility gene for autism spectrum disorders that is mutated in a neurodevelopmental syndrome, encodes a mitochondrial aspartate-glutamate carrier (aspartate-glutamate carrier isoform 1 [AGC1]). AGC1 is an important component of the malate/aspartate shuttle, a crucial system supporting oxidative phosphorylation and adenosine triphosphate production. We characterized mice with a disruption of the Slc25a12 gene, followed by confirmatory in vitro studies. Slc25a12-knockout mice, which showed no AGC1 by immunoblotting, were born normally but displayed delayed development and died around 3 weeks after birth. In postnatal day 13 to 14 knockout brains, the brains were smaller with no obvious alteration in gross structure. However, we found a reduction in myelin basic protein (MBP)-positive fibers, consistent with a previous report. Furthermore, the neocortex of knockout mice contained abnormal neurofilamentous accumulations in neurons, suggesting defective axonal transport and/or neurodegeneration. Slice cultures prepared from knockout mice also showed a myelination defect, and reduction of Slc25a12 in rat primary oligodendrocytes led to a cell-autonomous reduction in MBP expression. Myelin deficits in slice cultures from knockout mice could be reversed by administration of pyruvate, indicating that reduction in AGC1 activity leads to reduced production of aspartate/N-acetylaspartate and/or alterations in the dihydronicotinamide adenine dinucleotide/nicotinamide adenine dinucleotide(+) ratio, resulting in myelin defects. Our data implicate AGC1 activity in myelination and in neuronal structure and indicate that while loss of AGC1 leads to hypomyelination and neuronal changes, subtle alterations in AGC1 expression could affect brain development, contributing to increased autism susceptibility. Copyright 2010 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  6. The Impact of Technology on the Work Force.

    ERIC Educational Resources Information Center

    Braden, Paul V.

    1988-01-01

    Examines factors affecting the nation's present and future workforce: rapid technological advancements; other nations' use of advanced technologies and industrial targeting strategies; demographic factors; and changing values in the workplace. Sees needs for lifelong skills retraining, efforts to ensure industrial competitiveness, new…

  7. GD SDR Automatic Gain Control Characterization Testing

    NASA Technical Reports Server (NTRS)

    Nappier, Jennifer M.; Briones, Janette C.

    2013-01-01

    The General Dynamics (GD) S-Band software defined radio (SDR) in the Space Communications and Navigation (SCAN) Testbed on the International Space Station (ISS) will provide experimenters an opportunity to develop and demonstrate experimental waveforms in space. The GD SDR platform and initial waveform were characterized on the ground before launch and the data will be compared to the data that will be collected during on-orbit operations. A desired function of the SDR is to estimate the received signal to noise ratio (SNR), which would enable experimenters to better determine on-orbit link conditions. The GD SDR does not have an SNR estimator, but it does have an analog and a digital automatic gain control (AGC). The AGCs can be used to estimate the SDR input power which can be converted into a SNR. Tests were conducted to characterize the AGC response to changes in SDR input power and temperature. This purpose of this paper is to describe the tests that were conducted, discuss the results showi ng how the AGCs relate to the SDR input power, and provide recommendations for AGC testing and characterization.

  8. GD SDR Automatic Gain Control Characterization Testing

    NASA Technical Reports Server (NTRS)

    Nappier, Jennifer M.; Briones, Janette C.

    2013-01-01

    The General Dynamics (GD) S-Band software defined radio (SDR) in the Space Communications and Navigation (SCAN) Testbed on the International Space Station (ISS) will provide experimenters an opportunity to develop and demonstrate experimental waveforms in space. The GD SDR platform and initial waveform were characterized on the ground before launch and the data will be compared to the data that will be collected during on-orbit operations. A desired function of the SDR is to estimate the received signal to noise ratio (SNR), which would enable experimenters to better determine on-orbit link conditions. The GD SDR does not have an SNR estimator, but it does have an analog and a digital automatic gain control (AGC). The AGCs can be used to estimate the SDR input power which can be converted into a SNR. Tests were conducted to characterize the AGC response to changes in SDR input power and temperature. This purpose of this paper is to describe the tests that were conducted, discuss the results showing how the AGCs relate to the SDR input power, and provide recommendations for AGC testing and characterization.

  9. Making technological innovation work for sustainable development.

    PubMed

    Anadon, Laura Diaz; Chan, Gabriel; Harley, Alicia G; Matus, Kira; Moon, Suerie; Murthy, Sharmila L; Clark, William C

    2016-08-30

    This paper presents insights and action proposals to better harness technological innovation for sustainable development. We begin with three key insights from scholarship and practice. First, technological innovation processes do not follow a set sequence but rather emerge from complex adaptive systems involving many actors and institutions operating simultaneously from local to global scales. Barriers arise at all stages of innovation, from the invention of a technology through its selection, production, adaptation, adoption, and retirement. Second, learning from past efforts to mobilize innovation for sustainable development can be greatly improved through structured cross-sectoral comparisons that recognize the socio-technical nature of innovation systems. Third, current institutions (rules, norms, and incentives) shaping technological innovation are often not aligned toward the goals of sustainable development because impoverished, marginalized, and unborn populations too often lack the economic and political power to shape innovation systems to meet their needs. However, these institutions can be reformed, and many actors have the power to do so through research, advocacy, training, convening, policymaking, and financing. We conclude with three practice-oriented recommendations to further realize the potential of innovation for sustainable development: (i) channels for regularized learning across domains of practice should be established; (ii) measures that systematically take into account the interests of underserved populations throughout the innovation process should be developed; and (iii) institutions should be reformed to reorient innovation systems toward sustainable development and ensure that all innovation stages and scales are considered at the outset.

  10. Making technological innovation work for sustainable development

    PubMed Central

    Anadon, Laura Diaz; Harley, Alicia G.; Matus, Kira; Moon, Suerie; Murthy, Sharmila L.

    2016-01-01

    This paper presents insights and action proposals to better harness technological innovation for sustainable development. We begin with three key insights from scholarship and practice. First, technological innovation processes do not follow a set sequence but rather emerge from complex adaptive systems involving many actors and institutions operating simultaneously from local to global scales. Barriers arise at all stages of innovation, from the invention of a technology through its selection, production, adaptation, adoption, and retirement. Second, learning from past efforts to mobilize innovation for sustainable development can be greatly improved through structured cross-sectoral comparisons that recognize the socio-technical nature of innovation systems. Third, current institutions (rules, norms, and incentives) shaping technological innovation are often not aligned toward the goals of sustainable development because impoverished, marginalized, and unborn populations too often lack the economic and political power to shape innovation systems to meet their needs. However, these institutions can be reformed, and many actors have the power to do so through research, advocacy, training, convening, policymaking, and financing. We conclude with three practice-oriented recommendations to further realize the potential of innovation for sustainable development: (i) channels for regularized learning across domains of practice should be established; (ii) measures that systematically take into account the interests of underserved populations throughout the innovation process should be developed; and (iii) institutions should be reformed to reorient innovation systems toward sustainable development and ensure that all innovation stages and scales are considered at the outset. PMID:27519800

  11. Advances in Systemic Therapy for Metastatic or Advanced Gastric Cancer.

    PubMed

    Shitara, Kohei; Ohtsu, Atsushi

    2016-10-01

    In recent years, various new agents have been investigated for the treatment of advanced gastric cancer (AGC). The anti-HER2 antibody trastuzumab has been shown to prolong the overall survival of patients with HER2-positive AGC and has become a standard treatment. However, lapatinib, or ado-trastuzumab emtansine (T-DM1), did not show survival benefit in AGC, although it has shown remarkable efficacy for HER2-positive breast cancer. The efficacy of the anti-vascular endothelial growth factor receptor monoclonal antibody ramucirumab for pretreated gastric cancer is a milestone for antiangiogenic therapy for AGC. Early clinical trials of TAS-118, TAS-102, and STAT3 inhibitors; IMAB362 (anti-Claudin 18.2); and immune checkpoint inhibitors are all encouraging. These findings warrant further evaluation in larger clinical trials. Copyright © 2016 by the National Comprehensive Cancer Network.

  12. "Kaizen" and Technology Transfer Instructors as Work-based Learning Facilitators in Overseas Transplants: A Case Study.

    ERIC Educational Resources Information Center

    Elsey, Barry; Fujiwara, Asahi

    2000-01-01

    A study of 240 instructors of kaizen (continuous quality improvement) and technology transfer in overseas assignments for Toyota found that commitment to work and corporate cultural values were significant. Instructors recognized the responsibility and challenges of communicating and transferring their know-how across cultures. (SK)

  13. The Information and Communication Technology User Role: Implications for the Work Role and Inter-Role Spillover.

    PubMed

    Piszczek, Matthew M; Pichler, Shaun; Turel, Ofir; Greenhaus, Jeffrey

    2016-01-01

    Management and organization research has traditionally focused on employees' work role and the interface between their work and family roles. We suggest that persons assume a third role in modern society that is relevant to work and organizations, namely the Information and Communication Technology User (ICTU) role. Based on role theory and boundary theory, we develop propositions about the characteristics of this role, as well as how ICTU role characteristics are related to boundary spanning activity, inter-role spillover with the work role, and work role performance. To this end, we first conceptualize the ICTU role and its associations with work and family roles. We then apply identity theory and boundary management theory to advance our understanding of how the ICTU role is related to criteria that are important to individuals and to organizations, namely self-selection into certain types of work roles and positive and negative inter-role spillover. The implications of this role for theory, research, and practice in management and organizations are discussed.

  14. Making Technology Work for Campus Security

    ERIC Educational Resources Information Center

    Floreno, Jeff; Keil, Brad

    2010-01-01

    The challenges associated with securing schools from both on- and off-campus threats create constant pressure for law enforcement, campus security professionals, and administrators. And while security technology choices are plentiful, many colleges and universities are operating with limited dollars and information needed to select and integrate…

  15. Feasibility study: Atmospheric general circulation experiment, volume 2

    NASA Technical Reports Server (NTRS)

    Homsey, R. J. (Editor)

    1981-01-01

    The feasibility analysis of the atmospheric general circulation experiment (AGCE) are documented. The analysis performed in each technical area, the rationale and substantiation for the design approaches selected for the hardware, and the design details for the baseline AGCE are presented.

  16. The Institute Bibliography 1990: Published and Unpublished Work by Members of the Institute of Educational Technology, 1990 [and] 1991 Supplement.

    ERIC Educational Resources Information Center

    Whitehead, Don J., Ed.

    This annotated bibliography is introduced by a description of the work of the Open University's Institute of Educational Technology (IET), which is concerned with all aspects of the academic work of the Open University and, increasingly, in wider spheres through its consultancy work and program of workshops on open and distance learning. The 1990…

  17. A Quantitative Study of Factors Contributing to Perceived Job Satisfaction of Information Technology Professionals Working in California Community Colleges

    ERIC Educational Resources Information Center

    Temple, James Christian

    2013-01-01

    Purpose: The purpose of this replication study was to understand job satisfaction factors (work, pay, supervision, people, opportunities for promotion, and job in general) as measured by the abridged Job Descriptive Index (aJDI) and the abridged Job in General (aJIG) scale for information technology (IT) professionals working in California…

  18. Comparison of efficacy and tolerance between combination therapy and monotherapy as first-line chemotherapy in elderly patients with advanced gastric cancer: Study protocol for a randomized controlled trial.

    PubMed

    Lee, Keun-Wook; Zang, Dae Young; Ryu, Min-Hee; Kim, Ki Hyang; Kim, Mi-Jung; Han, Hye Sook; Koh, Sung Ae; Park, Jin Hyun; Kim, Jin Won; Nam, Byung-Ho; Choi, In Sil

    2017-12-01

    The combination of a fluoropyrimidine [5-fluorouracil (5-FU), capecitabine, or S-1] with a platinum analog (cisplatin or oxaliplatin) is the most widely accepted first-line chemotherapy regimen for metastatic or recurrent advanced gastric cancer (AGC), based on the results of clinical trials. However, there is little evidence to guide chemotherapy for elderly patients with AGC because of under-representation of this age group in clinical trials. Thus, the aim of this study is to determine the optimal chemotherapy regimen for elderly patients with AGC by comparing the efficacies and safeties of combination therapy versus monotherapy as first-line chemotherapy. This study is a randomized, controlled, multicenter, phase III trial. A total of 246 elderly patients (≥70 years old) with metastatic or recurrent AGC who have not received previous palliative chemotherapy will be randomly allocated to a combination therapy group or a monotherapy group. Patients randomized to the combination therapy group will receive fluoropyrimidine plus platinum combination chemotherapy (capecitabine/cisplatin, S-1/cisplatin, capecitabine/oxaliplatin, or 5-FU/oxaliplatin), and those randomized to the monotherapy group will receive fluoropyrimidine monotherapy (capecitabine, S-1, or 5-FU). The primary outcome is the overall survival of patients in each treatment group. The secondary outcomes include progression-free survival, response rate, quality of life, and safety. We are conducting this pragmatic trial to determine whether elderly patients with AGC will obtain the same benefit from chemotherapy as younger patients. We expect that this study will help guide decision-making for the optimal treatment of elderly patients with AGC.

  19. The Information and Communication Technology User Role: Implications for the Work Role and Inter-Role Spillover

    PubMed Central

    Piszczek, Matthew M.; Pichler, Shaun; Turel, Ofir; Greenhaus, Jeffrey

    2016-01-01

    Management and organization research has traditionally focused on employees’ work role and the interface between their work and family roles. We suggest that persons assume a third role in modern society that is relevant to work and organizations, namely the Information and Communication Technology User (ICTU) role. Based on role theory and boundary theory, we develop propositions about the characteristics of this role, as well as how ICTU role characteristics are related to boundary spanning activity, inter-role spillover with the work role, and work role performance. To this end, we first conceptualize the ICTU role and its associations with work and family roles. We then apply identity theory and boundary management theory to advance our understanding of how the ICTU role is related to criteria that are important to individuals and to organizations, namely self-selection into certain types of work roles and positive and negative inter-role spillover. The implications of this role for theory, research, and practice in management and organizations are discussed. PMID:28082936

  20. Commutated automatic gain control system

    NASA Technical Reports Server (NTRS)

    Yost, S. R.

    1982-01-01

    The commutated automatic gain control (AGC) system was designed and built for the prototype Loran-C receiver is discussed. The current version of the prototype receiver, the Mini L-80, was tested initially in 1980. The receiver uses a super jolt microcomputer to control a memory aided phase loop (MAPLL). The microcomputer also controls the input/output, latitude/longitude conversion, and the recently added AGC system. The AGC control adjusts the level of each station signal, such that the early portion of each envelope rise is about at the same amplitude in the receiver envelope detector.

  1. Component geochronology in the polyphase ca. 3920 Ma Acasta Gneiss

    USGS Publications Warehouse

    Mojzsis, Stephen J.; Cates, Nicole L.; Caro, Guillaume; Trail, Dustin; Abramov, Oleg; Guitreau, Martin; Blichert-Toft, Janne; Hopkins, Michelle D.; Bleeker, Wouter

    2014-01-01

    The oldest compiled U–Pb zircon ages for the Acasta Gneiss Complex in the Northwest Territories of Canada span about 4050–3850 Ma; yet older ca. 4200 Ma xenocrystic U–Pb zircon ages have also been reported for this terrane. The AGC expresses at least 25 km2 of outcrop exposure, but only a small subset of this has been documented in the detail required to investigate a complex history and resolve disputes over emplacement ages. To better understand this history, we combined new ion microprobe235,238U–207,206Pb zircon geochronology with whole-rock and zircon rare earth element compositions ([REE]zirc), Ti-in-zircon thermometry (Tixln) and 147Sm–143Nd geochronology for an individual subdivided ∼60 cm2 slab of Acasta banded gneiss comprising five separate lithologic components. Results were compared to other variably deformed granitoid-gneisses and plagioclase-hornblende rocks from elsewhere in the AGC. We show that different gneissic components carry distinct [Th/U]zirc vs. Tixln and [REE]zirc signatures correlative with different zircon U–Pb age populations and WR compositions, but not with 147Sm–143Nd isotope systematics. Modeled  [REE] from lattice-strain theory reconciles only the ca. 3920 Ma zircons with the oldest component that also preserves strong positive Eu∗ anomalies. Magmas which gave rise to the somewhat older (inherited) ca. 4020 Ma AGC zircon age population formed at ∼IW (iron–wüstite) to AGC is contemporaneous with bombardment of the inner solar system. Analytical bombardment simulations show that crustal re-working from the impact epoch potentially affected the precursors to the Acasta gneisses.

  2. Hospital Nurses' Work Activity in a Technology-Rich Environment: A Triangulated Quality Improvement Assessment.

    PubMed

    Higgins, Linda W; Shovel, Judith A; Bilderback, Andrew L; Lorenz, Holly L; Martin, Susan C; Rogers, Debra J; Minnier, Tamra E

    The aim of this project was to describe hospital nurses' work activity through observations, nurses' perceptions of time spent on tasks, and electronic health record time stamps. Nurses' attitudes toward technology and patients' perceptions and satisfaction with nurses' time at the bedside were also examined. Activities most frequently observed included documenting in and reviewing the electronic health record. Nurses' perceptions of time differed significantly from observations, and most patients rated their satisfaction with nursing time as excellent or good.

  3. eHealth Technology Competencies for Health Professionals Working in Home Care to Support Older Adults to Age in Place: Outcomes of a Two-Day Collaborative Workshop

    PubMed Central

    Barakat, Ansam; Woolrych, Ryan D; Sixsmith, Andrew; Kearns, William D

    2013-01-01

    Background The demand for care is increasing, whereas in the near future the number of people working in professional care will not match with the demand for care. eHealth technology can help to meet the growing demand for care. Despite the apparent positive effects of eHealth technology, there are still barriers to technology adoption related to the absence of a composite set of knowledge and skills among health care professionals regarding the use of eHealth technology. Objective The objective of this paper is to discuss the competencies required by health care professionals working in home care, with eHealth technologies such as remote telecare and ambient assisted living (AAL), mobile health, and fall detection systems. Methods A two-day collaborative workshop was undertaken with academics across multiple disciplines with experience in working on funded research regarding the application and development of technologies to support older people. Results The findings revealed that health care professionals working in home care require a subset of composite skills as well as technology-specific competencies to develop the necessary aptitude in eHealth care. This paper argues that eHealth care technology skills must be instilled in health care professionals to ensure that technologies become integral components of future care delivery, especially to support older adults to age in place. Educating health care professionals with the necessary skill training in eHealth care will improve service delivery and optimise the eHealth care potential to reduce costs by improving efficiency. Moreover, embedding eHealth care competencies within training and education for health care professionals ensures that the benefits of new technologies are realized by casting them in the context of the larger system of care. These care improvements will potentially support the independent living of older persons at home. Conclusions This paper describes the health care professionals

  4. eHealth Technology Competencies for Health Professionals Working in Home Care to Support Older Adults to Age in Place: Outcomes of a Two-Day Collaborative Workshop.

    PubMed

    Barakat, Ansam; Woolrych, Ryan D; Sixsmith, Andrew; Kearns, William D; Kort, Helianthe S M

    2013-01-01

    The demand for care is increasing, whereas in the near future the number of people working in professional care will not match with the demand for care. eHealth technology can help to meet the growing demand for care. Despite the apparent positive effects of eHealth technology, there are still barriers to technology adoption related to the absence of a composite set of knowledge and skills among health care professionals regarding the use of eHealth technology. The objective of this paper is to discuss the competencies required by health care professionals working in home care, with eHealth technologies such as remote telecare and ambient assisted living (AAL), mobile health, and fall detection systems. A two-day collaborative workshop was undertaken with academics across multiple disciplines with experience in working on funded research regarding the application and development of technologies to support older people. The findings revealed that health care professionals working in home care require a subset of composite skills as well as technology-specific competencies to develop the necessary aptitude in eHealth care. This paper argues that eHealth care technology skills must be instilled in health care professionals to ensure that technologies become integral components of future care delivery, especially to support older adults to age in place. Educating health care professionals with the necessary skill training in eHealth care will improve service delivery and optimise the eHealth care potential to reduce costs by improving efficiency. Moreover, embedding eHealth care competencies within training and education for health care professionals ensures that the benefits of new technologies are realized by casting them in the context of the larger system of care. These care improvements will potentially support the independent living of older persons at home. This paper describes the health care professionals' competencies and requirements needed for the use of e

  5. Geospatial Engineering

    DTIC Science & Technology

    2017-02-22

    manages operations through guidance, policies, programs, and organizations. The NSG is designed to be a mutually supportive enterprise that...deliberate technical design and deliberate human actions. Geospatial engineer teams (GETs) within the geospatial intelligence cells are the day-to-day...standards working group and are designated by the AGC Geospatial Acquisition Support Directorate as required for interoperability. Applicable standards

  6. Biochemical properties of Na+/K(+)-ATPase in axonal growth cone particles isolated from fetal rat brain.

    PubMed

    Mercado, R; Hernández, J

    1994-08-01

    Axonal growth cones (AGC) isolated from fetal rat brain have an important specific activity of N+/K(+)-ATPase. Kinetic assays of the enzyme in AGC showed that Km values for ATP or K+ are similar to those reported for the adult brain enzyme. For Na+ the affinity (Km) was lower. Vmax for the three substrates was several times lower in AGC as compared to the adult value. We also observed two apparent inhibition constants of Na+/K(+)-ATPase by ouabain, one of low affinity, possibly corresponding to the alpha 1 isoform and another of high affinity which is different to that described for the alpha 2 isoform of the enzyme. These results support an important role for the sodium pump in the maintainance of volume and cationic balance in neuronal differentiating structures. The functional differences observed also suggest that the enzymatic complex of Na+/K(+)-ATPase in AGC is in a transitional state towards the adult configuration.

  7. Hubble Space Telescope observations of the optical counterpart to a ultra-compact high-velocity cloud

    NASA Astrophysics Data System (ADS)

    Sand, David J.

    2017-01-01

    As part of a comprehensive archival search for optical counterparts to ultra-compact high-velocity clouds (UCHVCs), our team has uncovered five Local Volume dwarf galaxies, two of which were not previously known. Among these was AGC 226067, also known as ALFALFA-Dw1, which appeared to be made up of several HI and blue optical clumps based on ground-based data, with at least one HII region. Here we present Hubble Space Telescope Advanced Camera for Surveys data of AGC 226067. The data show that AGC 226067 is made up of a ~7-30 Myr old stellar population with a [Fe/H]~-0.6. Further, there is no evidence for an old stellar population associated with the system, down to a limit of MV>-8. Based on this and the position of AGC 226067 in the outskirts of the M86 subgroup of the Virgo cluster we present various arguments for the origin of this strange stellar system.

  8. Dynamics of cochlear nonlinearity: Automatic gain control or instantaneous damping?

    PubMed

    Altoè, Alessandro; Charaziak, Karolina K; Shera, Christopher A

    2017-12-01

    Measurements of basilar-membrane (BM) motion show that the compressive nonlinearity of cochlear mechanical responses is not an instantaneous phenomenon. For this reason, the cochlear amplifier has been thought to incorporate an automatic gain control (AGC) mechanism characterized by a finite reaction time. This paper studies the effect of instantaneous nonlinear damping on the responses of oscillatory systems. The principal results are that (i) instantaneous nonlinear damping produces a noninstantaneous gain control that differs markedly from typical AGC strategies; (ii) the kinetics of compressive nonlinearity implied by the finite reaction time of an AGC system appear inconsistent with the nonlinear dynamics measured on the gerbil basilar membrane; and (iii) conversely, those nonlinear dynamics can be reproduced using an harmonic oscillator with instantaneous nonlinear damping. Furthermore, existing cochlear models that include instantaneous gain-control mechanisms capture the principal kinetics of BM nonlinearity. Thus, an AGC system with finite reaction time appears neither necessary nor sufficient to explain nonlinear gain control in the cochlea.

  9. Anomalous diffusion of a probe in a bath of active granular chains

    NASA Astrophysics Data System (ADS)

    Jerez, Michael Jade Y.; Confesor, Mark Nolan P.; Carpio-Bernido, M. Victoria; Bernido, Christopher C.

    2017-08-01

    We investigate the dynamics of a passive probe particle in a bath of active granular chains (AGC). The bath and the probe are enclosed in an experimental compartment with a sinusoidal boundary to prevent AGC congestion along the boundary while connected to an electrodynamic shaker. Single AGC trajectory analysis reveals a persistent type of motion compared to a purely Brownian motion as seen in its mean squared displacement (MSD). It was found that at small concentration, Φ ≤ 0.44, the MSD exhibits two dynamical regimes characterized by two different scaling exponents. For small time scales, the dynamics is superdiffusive (1.32-1.63) with the MSD scaling exponent increasing monotonically with increasing AGC concentration. On the other hand, at long time, we recover the Brownian dynamics regime, MSD = DΔt, where the mobility D ∝ Φ. We quantify the probe dynamics at short time scale by modeling it as a fractional Brownian motion. The analytical form of the MSD agrees with experimental results.

  10. Automated Assume-Guarantee Reasoning for Omega-Regular Systems and Specifications

    NASA Technical Reports Server (NTRS)

    Chaki, Sagar; Gurfinkel, Arie

    2010-01-01

    We develop a learning-based automated Assume-Guarantee (AG) reasoning framework for verifying omega-regular properties of concurrent systems. We study the applicability of non-circular (AGNC) and circular (AG-C) AG proof rules in the context of systems with infinite behaviors. In particular, we show that AG-NC is incomplete when assumptions are restricted to strictly infinite behaviors, while AG-C remains complete. We present a general formalization, called LAG, of the learning based automated AG paradigm. We show how existing approaches for automated AG reasoning are special instances of LAG.We develop two learning algorithms for a class of systems, called infinite regular systems, that combine finite and infinite behaviors. We show that for infinity-regular systems, both AG-NC and AG-C are sound and complete. Finally, we show how to instantiate LAG to do automated AG reasoning for infinite regular, and omega-regular, systems using both AG-NC and AG-C as proof rules

  11. A sensitive and reproducible fluorescent-based HPLC assay to measure the activity of acid as well as neutral beta-glucocerebrosidases.

    PubMed

    Hayashi, Yasuhiro; Zama, Kouta; Abe, Eriko; Okino, Nozomu; Inoue, Takehiko; Ohno, Kousaku; Ito, Makoto

    2008-12-01

    The activity of lysosomal acid beta-glucocerebrosidase (AGC, EC 3.2.1.45), which hydrolyzes the O-glycosidic linkage between D-glucose and ceramide of glucosylceramide (GlcCer), is a marker for the diagnosis of Gaucher disease because the disease is caused by dysfunction of AGC due to mutations in the gene. The activity of AGC is potently inhibited by conduritol B epoxide (CBE), whereas CBE-insensitive nonlysosomal neutral beta-glucocerebrosidase (NGC) activities have been found in various vertebrates, including humans. We report here a new reliable method to determine AGC as well as NGC activities using normal-phase high-performance liquid chromatography (HPLC) and NBD (4-nitrobenzo-2-oxa-1,3-diazole)- or BODIPY (4,4-difluoro-4-boro-3a,4a-diaza-s-indacene)-labeled GlcCer as a substrate. The reaction products of the enzymes, C6-NBD-ceramide and C12-BODIPY-ceramide, were clearly separated from the corresponding substrates on a normal-phase column within 5 min using a different solvent system. Reaction products could be detected quantitatively at concentrations ranging from 50 fmol to 50 pmol for C6-NBD-ceramide and from 10 fmol to 5 pmol for C12-BODIPY-ceramide. V(max)/K(m) values of human fibroblast AGC for fluorescent GlcCer were much higher than those for 4-methylumbelliferyl-beta-d-glucoside (4MU-Glc), which is used prevalently for Gaucher disease diagnosis. As a result, AGC activity was detected quantitatively using fluorescent GlcCer, but not 4MU-Glc, using 5 microl of human serum or 1 x 10(4) cultured human fibroblasts. The current method clearly showed the decrease of AGC activities in fibroblasts and serum from the patient with Gaucher disease compared with normal individuals, suggesting that the method is applicable for the diagnosis of Gaucher disease. Furthermore, this method was found to be useful for measuring the activities of nonlysosomal NGC of various cells and tissues in the presence of CBE.

  12. Problems of reliability and economy work of thermal power plants water treatment based on baromembrane technologies

    NASA Astrophysics Data System (ADS)

    Chichirova, N. D.; Chichirov, A. A.; Saitov, S. R.

    2017-11-01

    The introduction of baromembrane water treatment technologies for water desalination at Russian thermal power plants was beganed more than 25 years ago. These technologies have demonstrated their definite advantage over the traditional technologies of additional water treatment for steam boilers. However, there are problems associated with the reliability and economy of their work. The first problem is a large volume of waste water (up to 60% of the initial water). The second problem a expensive and unique chemical reagents complex (biocides, antiscalants, washing compositions) is required for units stable and troublefree operation. Each manufacturer develops his own chemical composition for a certain membrane type. This leads to a significant increase in reagents cost, as well as creates dependence of the technology consumer on the certain supplier. The third problem is that the reliability of the baromembrane units depends directly on the water preliminary treatment. The popular pre-cleaning technology with coagulation of aluminum oxychloride proves to be unacceptable during seasonal changes in the quality of the source water at a number of stations. As a result, pollution, poisoning and lesion of the membrane structure or deterioration of their mechanical properties are observed. The report presents ways to solve these problems.

  13. National Commission on New Technological Uses of Copyrighted Works, Meeting Number Six (Arlington, Virginia, May 6, 1976).

    ERIC Educational Resources Information Center

    Library of Congress, Washington, DC. Copyright Office.

    With its sixth meeting, the National Commission on New Technological Uses of Copyrighted Works (CONTU) switched from substance to verbatim minutes. The first report, made by the president of the Computer and Business Equipment Manufacturers Association, dealt with the copyrightability or patentability of computer programs, protecting investments…

  14. [The eye of technology and the well being of women and men in Icelandic work places].

    PubMed

    Rafnsdóttir, Guobjörg Linda; Tómasson, Kristinn; Guomundsdóttir, Margrét Lilja

    2005-11-01

    The study assessed the association between working under surveillance and electronic performance monitoring and the well-being among women and men in six Icelandic workplaces. In the time period from February to April 2003, a questionnaire based on the General Nordic Questionnaire for Psychological and Social Factors at Work was delivered to 1369 employees in six companies where different methods of electronic performance monitoring (EPM) are used. The data was analyzed using odds ratio and logistical regression. The response rate was 72%, with close to equal participation of men and women. The employees who were working under EPM were more likely to have poor psychosocial work-environment, to have experienced significant stress recently, to be mentally exhausted at the end of the workday, to have significant sleep difficulties and to be dissatisfied in their job. The development of the information and communication technology that allows employers and managers to monitor and collect different electronic data about the work process and productivity of the workers makes it important to follow the health condition of those who work under electronic performance monitoring.

  15. Is the Use of Information and Communication Technology Related to Performance in Working Memory Tasks? Evidence from Seventh-Grade Students

    ERIC Educational Resources Information Center

    Garcia, Lucy; Nussbaum, Miguel; Preiss, David D.

    2011-01-01

    The main purpose of this study was to assess whether seventh-grade students use of information and communication technology (ICT) was related to performance on working memory tasks. In addition, the study tested whether the relationship between ICT use and performance on working memory tasks interacted with seventh-grade students' socioeconomic…

  16. Cytoplasmic Hu-Antigen R (HuR) Expression is Associated with Poor Survival in Patients with Surgically Resected Cholangiocarcinoma Treated with Adjuvant Gemcitabine-Based Chemotherapy.

    PubMed

    Toyota, Kazuhiro; Murakami, Yoshiaki; Kondo, Naru; Uemura, Kenichiro; Nakagawa, Naoya; Takahashi, Shinya; Sueda, Taijiro

    2018-05-01

    Hu-antigen R (HuR) is an RNA-binding protein that regulates the stability, translation, and nucleus-to-cytoplasm translocation of messenger RNAs (mRNAs). The aim of this study was to investigate the prognostic significance of HuR in cholangiocarcinoma patients who received adjuvant gemcitabine-based chemotherapy (AGC) after surgical resection. Nuclear and cytoplasmic HuR expression was investigated immunohistochemically in 131 patients with resected cholangiocarcinoma, including 91 patients administered AGC and 40 patients who did not receive adjuvant chemotherapy. The correlation between HuR expression and survival was evaluated by statistical analysis. High nuclear and cytoplasmic HuR expression was observed in 67 (51%) and 45 (34%) patients, respectively. Cytoplasmic HuR expression was significantly associated with lymph node metastasis (p < 0.01), while high cytoplasmic HuR expression was significantly associated with poor disease-free survival [DFS] (p = 0.03) and overall survival [OS] (p = 0.001) in the 91 patients who received AGC, but not in the 40 patients who did not receive AGC (DFS p = 0.17; OS p = 0.07). In the multivariate analysis of patients who received AGC, high cytoplasmic HuR expression was an independent predictor of poor DFS (hazard ratio [HR] 1.77; p = 0.04) and OS (HR 2.09; p = 0.02). Nuclear HuR expression did not affect the survival of enrolled patients. High cytoplasmic HuR expression was closely associated with the efficacy of AGC in patients with cholangiocarcinoma. The current findings warrant further investigations to optimize adjuvant chemotherapy regimens for resectable cholangiocarcinoma.

  17. Atypical glandular cells in cervical smears: histological correlation and a suggested plan of management based on age of the patient in a low-resource setting.

    PubMed

    Adhya, A K; Mahesha, V; Srinivasan, R; Nijhawan, R; Rajwanshi, A; Suri, V; Dhaliwal, L K

    2009-12-01

    To perform an audit of all smears reported as atypical glandular cells (AGC) using the Bethesda system (TBS) 2001. A total of 18 376 cervical smears were screened from January 2005 to June 2007, of which 65 cases were reported as AGC. Follow-up histology was available in 31 cases (47.7%), in whom a detailed cytological/histological correlation was carried out. AGC constituted 0.35% of all Pap smears. Follow-up histology was normal or benign in 20 cases, whereas a squamous or glandular abnormality was seen in 11 cases. Squamous abnormalities included one case each of cervical intraepithelial neoplasia (CIN)1, CIN2 and CIN3 and five cases of squamous cell carcinoma. All glandular epithelial abnormalities were endometrial in origin and included two endometrial adenocarcinomas and one uterine serous carcinoma. Neither in situ nor invasive adenocarcinoma of the endocervix was observed. Review of smears and reclassification as AGC, not otherwise specified and favour neoplasia revealed a higher proportion of abnormality in the latter group, reaffirming the utility of subtyping. The median age of women with AGC was 41 years. The outcome was analysed with respect to the median age. In women aged equal or more than 40 years, AGC reflected a high-grade squamous or glandular epithelial abnormality in 50% of cases compared with none in those less than 40 years old (P = 0.010). The age of the woman as well as the subtype of atypical glandular cells influences outcome and hence must be taken into consideration while formulating an acceptable management strategy in these women in a low-resource setting.

  18. Report of the Data Base Subcommittee to the National Commission on New Technological Uses of Copyrighted Works.

    ERIC Educational Resources Information Center

    National Commission on New Technological Uses of Copyrighted Works, Washington, DC.

    The agreement of the National Commission on New Technological Uses of Copyrighted Works (CONTU) with the legislative intent of the new copyright law, which accords copyright protection for computer data bases equivalent with the protection accorded compilations in traditional hard-copy format, includes several problem areas: (1) What copyright…

  19. Work-Centered Technology Development (WTD)

    DTIC Science & Technology

    2005-03-01

    theoretical, testable, inductive, and repeatable foundations of science. o Theoretical foundations include notions such as statistical versus analytical...Human Factors and Ergonomics Society, 263-267. 179 Eggleston, R. G. (2005). Coursebook : Work-Centered Design (WCD). AFRL/HECS WCD course training

  20. Cutting the Distance in Distance Education: Reflections on the Use of E-Technologies in a New Zealand Social Work Program

    ERIC Educational Resources Information Center

    Stanley-Clarke, Nicky; English, Awhina; Yeung, Polly

    2018-01-01

    The development of new e-technologies and an increased focus on developing distance social work education programs has created the impetus for social work educators to consider the tools they can employ in delivering distance courses. This article reflects on an action learning research project involving the development of an online toolbox of…

  1. Age-Related DNA Methylation Changes and Neoplastic Transformation of the Human Prostate

    DTIC Science & Technology

    2011-07-01

    Vol. 4 Issue 1 Figure 4. Methylation and expression analysis of the Sprouty1. (A) Representative program traces for Sprouty1. Gray colums represents...5’-ggt acc CCC TCC TGA GCT CAT GGT AAC CT-3’ Fwd 6 (-509) 5’-ggt acc CTT CTG GTT TGG AGC ACA GTG CAA AG-3’ Fwd 5 (-1318) 5’ggt acc AGA AGA CCT...CCC GAG GTG GAT GTT A-3’ Fwd3 (-2025) 5’-ggt acc CTG TCA ATC ACC GGG AGC-3’ Reverse (+8) 5’-gct agc AAT CCG CAC TGA ATA AAT AGT TGA C-3’. For

  2. Telecommuting to Work: Using Technology to Work at Home.

    ERIC Educational Resources Information Center

    Luce, Richard E.; Hartman, Susan

    1984-01-01

    Describes experience of Boulder Public Library, where management and support personnel established pre-experiment baseline data for comparison with quantitative and qualitative results of experiment to determine the impact of telecommuting (work-at-home) on worker productivity. Background, methodology, equipment enhancements, and data analysis are…

  3. Design of a wideband CMOS impedance spectroscopy ASIC analog front-end for multichannel biosensor interfaces.

    PubMed

    Valente, Virgilio; Dai Jiang; Demosthenous, Andreas

    2015-08-01

    This paper presents the preliminary design and simulation of a flexible and programmable analog front-end (AFE) circuit with current and voltage readout capabilities for electric impedance spectroscopy (EIS). The AFE is part of a fully integrated multifrequency EIS platform. The current readout comprises of a transimpedance stage and an automatic gain control (AGC) unit designed to accommodate impedance changes larger than 3 order of magnitude. The AGC is based on a dynamic peak detector that tracks changes in the input current over time and regulates the gain of a programmable gain amplifier in order to optimise the signal-to-noise ratio. The system works up to 1 MHz. The voltage readout consists of a 2 stages of fully differential current-feedback instrumentation amplifier which provide 100 dB of CMRR and a programmable gain up to 20 V/V per stage with a bandwidth in excess of 10MHz.

  4. Barriers to the use of Information and Communication Technology by occupational therapists working in a rural area of New South Wales, Australia.

    PubMed

    Chedid, Rebecca Jean; Dew, Angela; Veitch, Craig

    2013-06-01

    This qualitative study formed part of a large-scale, multi-phase study into the delivery of therapy services to people with a disability, living in one rural area of New South Wales, Australia. The study's purpose was to identify the impact of Information and Communication Technology on the workforce practices of occupational therapists' working in a rural area of New South Wales. Individual semi-structured telephone interviews were conducted with 13 occupational therapists working in disability, health and private practice in a rural area of New South Wales. Participants were asked about access to, skills and limitations of using Information and Communication Technology. A modified grounded theory approach, based on thematic analysis and constant comparison, was used to analyse the interview transcripts. This study found widespread use of technology by rurally based occupational therapists working in the disability sector in New South Wales. However, Information and Communication Technology was primarily used for client contact, professional development and professional networking rather than therapy provision. The study identified individual, workplace and community barriers to greater uptake of Information and Communication Technology by this group. The individual barriers included: age cohort, knowledge and personal preferences. The workplace barriers included: support and training and availability of resources. The community barriers included: infrastructure and perceptions of clients' acceptance. The potential exists for Information and Communication Technology to supplement face-to-face therapy provision, enhance access to professional development and reduce professional isolation thereby addressing the rural challenges of large distances, travel times and geographic isolation. To overcome these challenges, individual, workplace and community Information and Communication Technology barriers should be addressed concurrently. © 2012 The Authors Australian

  5. Technology Partnership Organization: Quality Work Force Planning in East Texas. Final Report for Project Year 1990-1991.

    ERIC Educational Resources Information Center

    Fabac, John N.

    The Technology Partnership Organization (TPO) is one of 24 Quality Work Force Planning (QWFP) entities in Texas. The TPO met its objectives through a variety of activities, including the following: (1) establishing a QWFP committee for the region; (2) providing an inventory of key regional industries with the greatest job opening potential and…

  6. RadWorks Project. ISS REM - to - BIRD - to - HERA: The Evolution of a Technology

    NASA Technical Reports Server (NTRS)

    McLeod, Catherine D.

    2015-01-01

    The advancement of particle detectors based on technologies developed for use in high-energy physics applications has enabled the development of a completely new generation of compact low-power active dosimeters and area monitors for use in space radiation environments. One such device, the TimePix, is being developed at CERN, and is providing the technology basis for the most recent line of radiation detection devices being developed by the NASA AES RadWorks project. The most fundamental of these devices, an ISS-Radiation Environment Monitor (REM), is installed as a USB device on ISS where it is monitoring the radiation environment on a perpetual basis. The second generation of this TimePix technology, the BIRD (Battery-operated Independent Radiation Detector), was flown on the NASA EFT-1 flight in December 2014. Data collected by BIRD was the first data made available from the Trapped Belt region of the Earth's atmosphere in over 40 years. The 3rdgeneration of this technology, the HERA (Hybrid Electronic Radiation Assessor), is planned to be integrated into the Orion EM-1, and EM-2 vehicles where it will monitor the radiation environment. For the EM-2 flight, HERA will provide Caution and Warning notification for SPEs as well as real time dose measurements for crew members. The development of this line of radiation detectors provide much greater information and characterization of charged particles in the space radiation environment than has been collected in the past, and in the process provide greater information to inform crew members of radiation related risks, while being very power and mass efficient.

  7. Pharmacy in transition: A work sampling study of community pharmacists using smartphone technology.

    PubMed

    van de Pol, Jeroen M; Geljon, Jurjen G; Belitser, Svetlana V; Frederix, Geert W J; Hövels, Anke M; Bouvy, Marcel L

    2018-03-09

    The nature of community pharmacy is changing, shifting from the preparation and distribution of medicines to the provision of cognitive pharmaceutical services (CPS); however, often the provision of traditional services leaves little time for innovative services. This study investigated the time community pharmacists spend on the tasks and activities of daily practice and to what extent they are able to implement CPS-related services in daily practice. Self-reporting work sampling was used to register the activities of community pharmacists. A smartphone application, designed specifically for this purpose, alerted participants to register their current activity five times per working day for 6 weeks. Participants also completed an online survey about baseline characteristics. Ninety-one Dutch community pharmacists provided work-sampling data (7848 registered activities). Overall, 51.5% of their time was spent on professional activities, 35.4% on semi-professional activities, and 13.1% on non-professional activities. The proportion of time devoted to CPS decreased during the workweek, whereas the time spent on traditional task increased. This study shows it is feasible to collect work-sampling data using smartphone technology. Community pharmacists spent almost half of their time on semi-professional and non-professional activities, activities that could be delegated to other staff members. In practice, the transition to CPS is hampered by competing traditional tasks, which prevents community pharmacists from profiling themselves as pharmaceutical experts in daily practice. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  8. Flattening filter-free accelerators: a report from the AAPM Therapy Emerging Technology Assessment Work Group.

    PubMed

    Xiao, Ying; Kry, Stephen F; Popple, Richard; Yorke, Ellen; Papanikolaou, Niko; Stathakis, Sotirios; Xia, Ping; Huq, Saiful; Bayouth, John; Galvin, James; Yin, Fang-Fang

    2015-05-08

    This report describes the current state of flattening filter-free (FFF) radiotherapy beams implemented on conventional linear accelerators, and is aimed primarily at practicing medical physicists. The Therapy Emerging Technology Assessment Work Group of the American Association of Physicists in Medicine (AAPM) formed a writing group to assess FFF technology. The published literature on FFF technology was reviewed, along with technical specifications provided by vendors. Based on this information, supplemented by the clinical experience of the group members, consensus guidelines and recommendations for implementation of FFF technology were developed. Areas in need of further investigation were identified. Removing the flattening filter increases beam intensity, especially near the central axis. Increased intensity reduces treatment time, especially for high-dose stereotactic radiotherapy/radiosurgery (SRT/SRS). Furthermore, removing the flattening filter reduces out-of-field dose and improves beam modeling accuracy. FFF beams are advantageous for small field (e.g., SRS) treatments and are appropriate for intensity-modulated radiotherapy (IMRT). For conventional 3D radiotherapy of large targets, FFF beams may be disadvantageous compared to flattened beams because of the heterogeneity of FFF beam across the target (unless modulation is employed). For any application, the nonflat beam characteristics and substantially higher dose rates require consideration during the commissioning and quality assurance processes relative to flattened beams, and the appropriate clinical use of the technology needs to be identified. Consideration also needs to be given to these unique characteristics when undertaking facility planning. Several areas still warrant further research and development. Recommendations pertinent to FFF technology, including acceptance testing, commissioning, quality assurance, radiation safety, and facility planning, are presented. Examples of clinical

  9. Technology Transfer: Marketing Tomorrow's Technology

    NASA Technical Reports Server (NTRS)

    Tcheng, Erene

    1995-01-01

    The globalization of the economy and the end of the Cold War have triggered many changes in the traditional practices of U.S. industry. To effectively apply the resources available to the United States, the federal government has firmly advocated a policy of technology transfer between private industry and government labs, in this case the National Aeronautics and Space Administration (NASA). NASA Administrator Daniel Goldin is a strong proponent of this policy and has organized technology transfer or commercialization programs at each of the NASA field centers. Here at Langley Research Center, the Technology Applications Group (TAG) is responsible for facilitating the transfer of Langley developed research and technology to U.S. industry. Entering the program, I had many objectives for my summer research with TAG. Certainly, I wanted to gain a more thorough understanding of the concept of technology transfer and Langley's implementation of a system to promote it to both the Langley community and the community at large. Also, I hoped to become more familiar with Langley's research capabilities and technology inventory available to the public. More specifically, I wanted to learn about the technology transfer process at Langley. Because my mentor is a member of Materials and Manufacturing marketing sector of the Technology Transfer Team, another overriding objective for my research was to take advantage of his work and experience in materials research to learn about the Advanced Materials Research agency wide and help market these developments to private industry. Through the various projects I have been assigned to work on in TAG, I have successfully satisfied the majority of these objectives. Work on the Problem Statement Process for TAG as well as the development of the Advanced Materials Research Brochure have provided me with the opportunity to learn about the technology transfer process from the outside looking in and the inside looking out. Because TAG covers

  10. Work stress and subsequent risk of internet addiction among information technology engineers in Taiwan.

    PubMed

    Chen, Sung-Wei; Gau, Susan Shur-Fen; Pikhart, Hynek; Peasey, Anne; Chen, Shih-Tse; Tsai, Ming-Chen

    2014-08-01

    Work stress, as defined by the Demand-Control-Support (DCS) model and the Effort-Reward Imbalance (ERI) model, has been found to predict risks for depression, anxiety, and substance addictions, but little research is available on work stress and Internet addiction. The aims of this study are to assess whether the DCS and ERI models predict subsequent risks of Internet addiction, and to examine whether these associations might be mediated by depression and anxiety. A longitudinal study was conducted in a sample (N=2,550) of 21-55 year old information technology engineers without Internet addiction. Data collection included questionnaires covering work stress, demographic factors, psychosocial factors, substance addictions, Internet-related factors, depression and anxiety at wave 1, and the Internet Addiction Test (IAT) at wave 2. Ordinal logistic regression was used to assess the associations between work stress and IAT; path analysis was adopted to evaluate potentially mediating roles of depression and anxiety. After 6.2 months of follow-up, 14.0% of subjects became problematic Internet users (IAT 40-69) and 4.1% pathological Internet users (IAT 70-100). Job strain was associated with an increased risk of Internet addiction (odds ratio [OR] of having a higher IAT outcome vs. a lower outcome was 1.53); high work social support reduced the risk of Internet addiction (OR=0.62). High ER ratio (OR=1.61) and high overcommitment (OR=1.68) were associated with increased risks of Internet addiction. Work stress defined by the DCS and ERI models predicted subsequent risks of Internet addiction.

  11. Does Technology Integration "Work" when Key Barriers Are Removed?

    ERIC Educational Resources Information Center

    Lowther, Deborah L.; Inan, Fethi A.; Strahl, J. Daniel; Ross, Steven M.

    2008-01-01

    The effectiveness of Tennessee EdTech Launch (TnETL), a statewide technology program designed to meet the No Child Left Behind (NCLB) mandate, was investigated in this matched treatment-control quasi-experimental study. The goal of the program was to provide full-time, on-site technology coaches to prepare teachers to create lessons that engage…

  12. A review of filovirus work and facilities at the Defence Science and Technology Laboratory Porton Down.

    PubMed

    Smither, Sophie J; Lever, Mark S

    2012-08-01

    Porton Down houses two separate sites capable of conducting high containment research on ACDP (Advisory Committee on Dangerous Pathogens) Hazard Group 4 agents: the Defence Science and Technology Laboratory (Dstl) and the Health Protection Agency (HPA), and filovirus research has been performed at Porton Down since the first Marburg virus disease outbreak in 1967. All work is conducted within primary containment either within cabinet lines (for in vitro work) or large rigid half-suit isolators (for in vivo work). There are extensive aerobiological facilities at high containment and the use of these facilities will be reported. Research at Dstl is primarily focused on assessing and quantifying the hazard, and testing the efficacy of medical countermeasures against filoviruses. Fundamental research directed to the study and understanding of the infectious and pathogenic nature of the filoviruses, particularly in aerosols, will be reported.

  13. A Review of Filovirus Work and Facilities at The Defence Science and Technology Laboratory Porton Down

    PubMed Central

    Smither, Sophie J.; Lever, Mark S.

    2012-01-01

    Porton Down houses two separate sites capable of conducting high containment research on ACDP (Advisory Committee on Dangerous Pathogens) Hazard Group 4 agents: the Defence Science and Technology Laboratory (Dstl) and the Health Protection Agency (HPA), and filovirus research has been performed at Porton Down since the first Marburg virus disease outbreak in 1967. All work is conducted within primary containment either within cabinet lines (for in vitro work) or large rigid half-suit isolators (for in vivo work). There are extensive aerobiological facilities at high containment and the use of these facilities will be reported. Research at Dstl is primarily focused on assessing and quantifying the hazard, and testing the efficacy of medical countermeasures against filoviruses. Fundamental research directed to the study and understanding of the infectious and pathogenic nature of the filoviruses, particularly in aerosols, will be reported. PMID:23012627

  14. Tree species diversity promotes aboveground carbon storage through functional diversity and functional dominance.

    PubMed

    Mensah, Sylvanus; Veldtman, Ruan; Assogbadjo, Achille E; Glèlè Kakaï, Romain; Seifert, Thomas

    2016-10-01

    The relationship between biodiversity and ecosystem function has increasingly been debated as the cornerstone of the processes behind ecosystem services delivery. Experimental and natural field-based studies have come up with nonconsistent patterns of biodiversity-ecosystem function, supporting either niche complementarity or selection effects hypothesis. Here, we used aboveground carbon (AGC) storage as proxy for ecosystem function in a South African mistbelt forest, and analyzed its relationship with species diversity, through functional diversity and functional dominance. We hypothesized that (1) diversity influences AGC through functional diversity and functional dominance effects; and (2) effects of diversity on AGC would be greater for functional dominance than for functional diversity. Community weight mean (CWM) of functional traits (wood density, specific leaf area, and maximum plant height) were calculated to assess functional dominance (selection effects). As for functional diversity (complementarity effects), multitrait functional diversity indices were computed. The first hypothesis was tested using structural equation modeling. For the second hypothesis, effects of environmental variables such as slope and altitude were tested first, and separate linear mixed-effects models were fitted afterward for functional diversity, functional dominance, and both. Results showed that AGC varied significantly along the slope gradient, with lower values at steeper sites. Species diversity (richness) had positive relationship with AGC, even when slope effects were considered. As predicted, diversity effects on AGC were mediated through functional diversity and functional dominance, suggesting that both the niche complementarity and the selection effects are not exclusively affecting carbon storage. However, the effects were greater for functional diversity than for functional dominance. Furthermore, functional dominance effects were strongly transmitted by CWM of

  15. Using Genetic Buffering Relationships Identified in Fission Yeast To Elucidate the Molecular Pathology of Tuberous Sclerosis

    DTIC Science & Technology

    2016-07-01

    5’-aat tat ttt ata tgg aat gag caa gta tgt ttt atc ata att gac cag ttc att tca agg acc ttc aaa aat ata cct acg aat tcg agc tcg ttt aaa c-3’), or...oTsc13 (5’-tta aga gtt cag att tgc ttt atg tgg tta ttc tgc tga agg tcc taa ttt att gac gtt gaa aaa taa agg cca cat agc gga tcc ccg ggt taa tta a-3...and oTsc14 (5’-ata aaa aaa att aat taa tga tgg caa ggc aca atc gta atc aat ctt tta att tag gac ttt tta tat gcc ctt atg gcg aat tcg agc tcg ttt aaa c

  16. Results of a national survey indicating information technology skills needed by nurses at time of entry into the work force.

    PubMed

    McCannon, Melinda; O'Neal, Pamela V

    2003-08-01

    A national survey was conducted to determine the information technology skills nurse administrators consider critical for new nurses entering the work force. The sample consisted of 2,000 randomly selected members of the American Organization of Nurse Executives. Seven hundred fifty-two usable questionnaires were returned, for a response rate of 38%. The questionnaire used a 5-point Likert scale and consisted of 17 items that assessed various technology skills and demographic information. The questionnaire was developed and pilot tested with content experts to establish content validity. Descriptive analysis of the data revealed that using e-mail effectively, operating basic Windows applications, and searching databases were critical information technology skills. The most critical information technology skill involved knowing nursing-specific software, such as bedside charting and computer-activated medication dispensers. To effectively prepare nursing students with technology skills needed at the time of entry into practice, nursing faculty need to incorporate information technology skills into undergraduate nursing curricula.

  17. Clinical social work practice and technology: personal, practical, regulatory, and ethical considerations for the twenty-first century.

    PubMed

    Dombo, Eileen A; Kays, Lisa; Weller, Katelyn

    2014-10-01

    The world that social work exists in is no longer defined by traditional physical settings and boundaries, such as schools, agencies, or even offices. With the advent of the Internet and digital communications, social work now exists in a far more complex reality, with clients and social workers engaging across multiple platforms, and sometimes even unintentionally and without one another's awareness. The implications of this can be ethical, practical, regulatory, and personal. This article explores these areas of concern and suggests strategies professionals can use to navigate these complex issues related to technology and clinical practice.

  18. The space shuttle payload planning working groups. Volume 10: Space technology

    NASA Technical Reports Server (NTRS)

    1973-01-01

    The findings and recommendations of the Space Technology group of the space shuttle payload planning activity are presented. The elements of the space technology program are: (1) long duration exposure facility, (2) advanced technology laboratory, (3) physics and chemistry laboratory, (4) contamination experiments, and (5) laser information/data transmission technology. The space technology mission model is presented in tabular form. The proposed experiments to be conducted by each test facility are described. Recommended approaches for user community interfacing are included.

  19. National Commission on New Technological Uses of Copyrighted Works (CONTU), Seventh Meeting (Arlington, Virginia, June 9-10, 1976).

    ERIC Educational Resources Information Center

    Library of Congress, Washington, DC. Copyright Office.

    Presentations at the June 9-10, 1976, meeting of the National Commission on New Technological Uses of Copyrighted Works (CONTU) concentrated on computer software protection. There were a panel discussion, a briefing from a General Services Administration spokesman, and a presentation by representatives of the educational community. The testimony…

  20. [Effect of American Ginseng Capsule on the liver oxidative injury and the Nrf2 protein expression in rats exposed by electromagnetic radiation of frequency of cell phone].

    PubMed

    Luo, Ya-ping; Ma, Hui-Rong; Chen, Jing-Wei; Li, Jing-Jing; Li, Chun-xiang

    2014-05-01

    To observe the effect of American Ginseng Capsule (AGC) on the liver oxidative injury and the Nrf2 protein expression in the liver tissue of rats exposed by 900 MHz cell phone electromagnetic radiation. Totally 40 male SD rats were randomly divided into the normal control group, the model group, the Shuifei Jibin Capsule (SJC) group, and the AGC group,10 in each group. Rats in the normal control group were not irradiated. Rats in the rest three groups were exposed by imitated 900 MHz cellular phone for 4 h in 12 consecutive days. Meanwhile, rats in the SJC group and the AGC group were intragastrically administrated with suspension of SJC and AGC (1 mL/200 g body weight) respectively. Normal saline was administered to rats in the normal control group and the model group. The histolomorphological changes of the liver tissue were observed by HE staining. Contents of malonic dialdehyde (MDA), superoxide dismutase (SOD), glutathione (GSH), and glutathione peroxidase (GSH-PX)were detected by colorimetry. The Nrf2 protein expression of hepatocytes was detected by immunohistochemical assay and Western blot. Compared with the normal control group, hepatocyte nucleus was atrophied or partially disappeared, the contents of liver MDA and Nrf2 protein obviously increased (P <0. 05, P <0. 01); contents of liver SOD and GSH decreased (P <0. 05) in the model group. Compared with the model group, karyopyknosis was obviously attenuated and approached to the normal level in the SJC group and the AGC group. The contents of liver MDA and Nrf2 protein expression decreased (P <0. 05), and the contents of liver SOD, GSH, and GSH-PX obviously increased (P < 0.05) in the SJC group. The contents of liver MDA and the Nrf2 protein expression decreased (P < 0.05), and contents of SOD and GSH obviously increased in the AGC group (P <0.01, P <0.05). The electromagnetic radiation induced by 900 MHz cell phone could affect the expression of Nrf2 protein, induce oxidative injury, and induce abnormal

  1. Gender difference in work-family conflict among Japanese information technology engineers with preschool children.

    PubMed

    Watai, Izumi; Nishikido, Noriko; Murashima, Sachiyo

    2008-01-01

    Since the Family Policy Act, which requires companies to develop action plans to support their employees who have children in an attempt to reverse the declining birthrate in Japan, was enacted in 2003, many Japanese organizations and occupational health staff have become interested in work-family conflict (WFC), especially WFC in employees with young children. A cross-sectional survey of regularly employed information technology (IT) engineers with preschool children in Japan was conducted to examine the gender difference in WFC, relationship of WFC with outcomes, and predictors of WFC by gender. Data from 78 male and 102 female respondents were analyzed. There was no significant gender difference in total level of WFC. However, the level of work interference with family (WIF) was significantly higher in males than in females and the level of family interference with work (FIW) was significantly higher in females. Regarding outcomes, WIF was significantly related to depression and fatigue in both genders. Moreover, different predictors were related to WIF and FIW by gender. A family-friendly culture in the company was related to WIF only in males. To prevent depression and cumulative fatigue in employees with young children, occupational practitioners have to pay attention to not only employees' work stress but also their family stress or amount of family role in both genders.

  2. Robust PBPK/PD-Based Model Predictive Control of Blood Glucose.

    PubMed

    Schaller, Stephan; Lippert, Jorg; Schaupp, Lukas; Pieber, Thomas R; Schuppert, Andreas; Eissing, Thomas

    2016-07-01

    Automated glucose control (AGC) has not yet reached the point where it can be applied clinically [3]. Challenges are accuracy of subcutaneous (SC) glucose sensors, physiological lag times, and both inter- and intraindividual variability. To address above issues, we developed a novel scheme for MPC that can be applied to AGC. An individualizable generic whole-body physiology-based pharmacokinetic and dynamics (PBPK/PD) model of the glucose, insulin, and glucagon metabolism has been used as the predictive kernel. The high level of mechanistic detail represented by the model takes full advantage of the potential of MPC and may make long-term prediction possible as it captures at least some relevant sources of variability [4]. Robustness against uncertainties was increased by a control cascade relying on proportional-integrative derivative-based offset control. The performance of this AGC scheme was evaluated in silico and retrospectively using data from clinical trials. This analysis revealed that our approach handles sensor noise with a MARD of 10%-14%, and model uncertainties and disturbances. The results suggest that PBPK/PD models are well suited for MPC in a glucose control setting, and that their predictive power in combination with the integrated database-driven (a priori individualizable) model framework will help overcome current challenges in the development of AGC systems. This study provides a new, generic, and robust mechanistic approach to AGC using a PBPK platform with extensive a priori (database) knowledge for individualization.

  3. Predictors of Work-Family Role Conflict and Its Impact on Professional Women in Medicine, Engineering, and Information Technology in Nigeria.

    PubMed

    Uzoigwe, Anthonia Ginika; Low, Wah Yun; Noor, Siti Nurani Mohd

    2016-10-01

    This study examines work-family role conflict and the factors predicting it, with a sample of 173 professional women in engineering and information technology (IT) firms, including 2 hospitals-1 public and 1 private. Our findings show no significant difference in the level of work-family role conflict encountered by women across medicine, engineering, and IT, whereas hours of work, family responsibilities, job demand, and work role overload were significantly correlated with work-family role conflict. Multiple linear regression analysis indicates that only work role overload, family responsibilities, and hours of work significantly predicted 45.9% of work-family role conflict. This implies that working women are burdened by work demands, which invariably affects the work-family role conflict they experience and leads to deterioration of their occupational health. It is suggested that employers should create a flexible work schedule and establish family-friendly policies in the workplace to promote a healthy work-life balance for women in science careers.

  4. National Commission on New Technological Uses of Copyrighted Works (CONTU), Meeting Number One (Washington, D.C., October 8, 1975).

    ERIC Educational Resources Information Center

    Library of Congress, Washington, DC. Copyright Office.

    The first meeting of the National Commission on New Technological Uses of Copyrighted Works (CONTU) established some basic premises and procedures. Commissioners representing various interests concerned with copyright legislation (librarians, publishers, consumers and lawyers) discussed the responsibility of the Commission to review copyright…

  5. Active Work Zone Safety Using Emerging Technologies 2017.

    DOT National Transportation Integrated Search

    2017-07-01

    Highway construction work zones are hazardous environments characterized by a dynamic and limited work space. A host of interactions between workers, passing commuter vehicles, and moving construction equipment occurs in highway work zones fostering ...

  6. After the Biomedical Technology Revolution: Where to Now for a Bio-Psycho-Social Approach to Social Work?

    PubMed

    Healy, Karen

    2016-07-01

    In the late twentieth century, the bio-psycho-social framework emerged as a powerful influence on the conceptualisation and delivery of health and rehabilitation services including social work services in these fields. The bio-psycho-social framework is built on a systems view of health and well-being ( Garland and Howard, 2009). The systems perspective encourages medical and allied health professions, including social work, to recognise and to respond to the multiple systems impacting on individual health and well-being ( Engel, 2003). This paper analyses how advances in biomedical technology, particularly in the fields of neuroscience and human genomics, are challenging the bio-psycho-social approach to practice. The paper examines the pressures on the social work profession to embrace biomedical science and points to the problems in doing so. The conclusion points to some tentative ways forward for social workers to engage critically with biomedical advances and to strengthen the bio-psycho-social framework in the interests of holistic and ethical approaches to social work practice.

  7. Improving the effectiveness of smart work zone technologies.

    DOT National Transportation Integrated Search

    2016-11-01

    This project evaluates the effectiveness of sensor network systems for work zone traffic estimation. The comparative analysis is : performed on a work zone modeled in microsimulation and calibrated with field data from two Illinois work zones. Realis...

  8. The impact of computer display height and desk design on 3D posture during information technology work by young adults.

    PubMed

    Straker, L; Burgess-Limerick, R; Pollock, C; Murray, K; Netto, K; Coleman, J; Skoss, R

    2008-04-01

    Computer display height and desk design to allow forearm support are two critical design features of workstations for information technology tasks. However there is currently no 3D description of head and neck posture with different computer display heights and no direct comparison to paper based information technology tasks. There is also inconsistent evidence on the effect of forearm support on posture and no evidence on whether these features interact. This study compared the 3D head, neck and upper limb postures of 18 male and 18 female young adults whilst working with different display and desk design conditions. There was no substantial interaction between display height and desk design. Lower display heights increased head and neck flexion with more spinal asymmetry when working with paper. The curved desk, designed to provide forearm support, increased scapula elevation/protraction and shoulder flexion/abduction.

  9. Technology and Learning: Putting the Research To Work. Hot Topics Series.

    ERIC Educational Resources Information Center

    Moore, David M., Ed.; Lockee, Barbara B., Ed.; Moore, David R., Ed.

    This report focuses on the nature, use, and challenges of educational technology. The following articles are included: "Technology and Change for the Information Age" (James B. Ellsworth); "Education in a Digital Democracy: Leading the Charge for Learning about, with, and beyond Technology" (Mark David Milliron and Cindy L.…

  10. FCS Technology Investigation Overview

    NASA Technical Reports Server (NTRS)

    Budinger, James; Gilbert, Tricia

    2007-01-01

    This working paper provides an overview of the Future Communication Study (FCS) technology investigation progress. It includes a description of the methodology applied to technology evaluation; evaluation criteria; and technology screening (down select) results. A comparison of screening results with other similar technology screening activities is provided. Additional information included in this working paper is a description of in-depth studies (including characterization of the L-band aeronautical channel; L-band deployment cost assessment; and performance assessments of candidate technologies in the applicable aeronautical channel) that have been conducted to support technology evaluations. The paper concludes with a description on-going activities leading to conclusion of the technology investigation and the development of technology recommendations.

  11. Future Work. Myths and Realities No. 11.

    ERIC Educational Resources Information Center

    Kerka, Sandra

    In many of the stories foretelling the future of work, technology is assumed to be the irresistible driver of change. Both ends of the spectrum are foreseen: either technology will create new jobs and transform existing work to higher skill levels, or technology, especially information technology, will destroy jobs or degrade them into less…

  12. Training, age and technological change: difficulties associated with age, the design of tools, and the organization of work.

    PubMed

    Cau-Bareille, Dominique; Gaudart, Corinne; Delgoulet, Catherine

    2012-01-01

    This article presents two ergonomic studies carried out when two French administrative bodies modernized their work tools. Our objective was to identify and define the vocational learning of experienced technicians who were required to adopt new working methods to cope with these technological changes. We observed the work activity of technicians of different ages and length of service both before and during training, and also after their return to their work unit during the appropriation phase. These two studies revealed some difficulties that were common to all the technicians and others that were more specific to the older employees. In terms of the design of the training course, we were able to point out some mistaken assumptions about the technicians' original command of the work activity and the computers, which made it difficult for them to adopt new work procedures. The difficulties encountered by the older employees were ultimately found to be more an indication of organizational problems to do with the management of change rather than training problems due to age.

  13. Women in Technology: The Evolution of a Simple Program That Works.

    ERIC Educational Resources Information Center

    Crumb, Jean Marie; Fenton, Ray

    Three papers present views on women in technology programs and occupations, and on Corning Community College's (CCC's) program to encourage women to enter technological fields in which they have been historically underrepresented. First, Edward F. Herman presents the historical background to the development of CCC's Women in Technology program,…

  14. Molecular dietary analysis of two sympatric felids in the Mountains of Southwest China biodiversity hotspot and conservation implications

    PubMed Central

    Xiong, Mengyin; Wang, Dajun; Bu, Hongliang; Shao, Xinning; Zhang, Dan; Li, Sheng; Wang, Rongjiang; Yao, Meng

    2017-01-01

    Dietary information is lacking in most of small to mid-sized carnivores due to their elusive predatory behaviour and versatile feeding habits. The leopard cat (LPC; Prionailurus bengalensis) and the Asiatic golden cat (AGC; Catopuma temminckii) are two important yet increasingly endangered carnivore species in the temperate mountain forest ecosystem in Southwest China, a global biodiversity hotspot and a significant reservoir of China’s endemic species. We investigated the vertebrate prey of the two sympatric felids using faecal DNA and a next-generation sequencing (NGS)/metabarcoding approach. Forty vertebrate prey taxa were identified from 93 LPC and 10 AGC faecal samples; 37 taxa were found in the LPC diet, and 20 were detected in the AGC diet. Prey included 27 mammalian taxa, 11 birds, one lizard and one fish, with 73% (29/40) of the taxa assigned to the species level. Rodents and pikas were the most dominant LPC prey categories, whereas rodents, pheasant, fowl and ungulates were the main AGC prey. We also analysed the seasonal and altitudinal variations in the LPC diet. Our results provide the most comprehensive dietary data for these felids and valuable information for their conservation planning. PMID:28195150

  15. Engagement and Uncertainty: Emerging Technologies Challenge the Work of Engagement

    ERIC Educational Resources Information Center

    Eaton, Weston; Wright, Wynne; Whyte, Kyle; Gasteyer, Stephen P.; Gehrke, Pat J.

    2014-01-01

    Universities' increasing applications of science and technology to address a wide array of societal problems may serve to thwart democratic engagement strategies. For emerging technologies, such challenges are particularly salient, as knowledge is incomplete and application and impact are uncertain or contested. Insights from science and…

  16. IMPLEMENTATION OF HEALTH TECHNOLOGY ASSESSMENT WORK IN A HOSPITAL IN KAZAKHSTAN.

    PubMed

    Kosherbayeva, Lyazzat; Hailey, David; Kurakbaev, Kural; Tsoy, Aleksey; Zhuzzhanov, Ormanbek; Donbay, Abilay; Kumar, Ainur; Nadyrov, Kamalzhan

    2016-01-01

    The aim of this study was to implement health technology assessment (HA) in the First General City Hospital in Astana, Kazakhstan. We organized trainings to familiarize hospital staff with the purpose and details of HTA. An HTA committee was established, with representation from hospital physicians and managers, and criteria for prioritization of health technologies determined. Clinical departments of the hospital were asked to prepare applications for new technologies for their services. The HTA committee reviewed five applications and selected a technology from one of these, on single incision laparoscopic surgery (SILS), for assessment. A short HTA report on SILS was prepared, covering its safety, clinical effectiveness, and cost effectiveness. The report was used to support a request to the Department of Health for additional funding to implement this technology within the hospital. This funding was approved and SILS was established in several hospital departments. This successful initial experience with HTA has paved the way for its routine use by the hospital for informing decisions on the procurement and use of new health technologies.

  17. Group Work

    ERIC Educational Resources Information Center

    Wilson, Kristy J.; Brickman, Peggy; Brame, Cynthia J.

    2018-01-01

    Science, technology, engineering, and mathematics faculty are increasingly incorporating both formal and informal group work in their courses. Implementing group work can be improved by an understanding of the extensive body of educational research studies on this topic. This essay describes an online, evidence-based teaching guide published by…

  18. Using the CAE technologies of engineering analysis for designing steam turbines at ZAO Ural Turbine Works

    NASA Astrophysics Data System (ADS)

    Goloshumova, V. N.; Kortenko, V. V.; Pokhoriler, V. L.; Kultyshev, A. Yu.; Ivanovskii, A. A.

    2008-08-01

    We describe the experience ZAO Ural Turbine Works specialists gained from mastering the series of CAD/CAE/CAM/PDM technologies, which are modern software tools of computer-aided engineering. We also present the results obtained from mathematical simulation of the process through which high-and intermediate-pressure rotors are heated for revealing the most thermally stressed zones, as well as the results from mathematical simulation of a new design of turbine cylinder shells for improving the maneuverability of these turbines.

  19. Examining Educational Climate Change Technology: How Group Inquiry Work with Realistic Scientific Technology Alters Classroom Learning

    ERIC Educational Resources Information Center

    Bush, Drew; Sieber, Renee; Seiler, Gale; Chandler, Mark

    2018-01-01

    This study with 79 students in Montreal, Quebec, compared the educational use of a National Aeronautics and Space Administration (NASA) global climate model (GCM) to climate education technologies developed for classroom use that included simpler interfaces and processes. The goal was to show how differing climate education technologies succeed…

  20. The economic burden of advanced gastric cancer in Taiwan.

    PubMed

    Hong, Jihyung; Tsai, Yiling; Novick, Diego; Hsiao, Frank Chi-Huang; Cheng, Rebecca; Chen, Jen-Shi

    2017-09-16

    Gastric cancer is one of the leading causes of cancer-related deaths in both sexes worldwide, especially in Eastern Asia. This study aimed to estimate the economic burden of advanced gastric cancer (AGC) in Taiwan. The costs of AGC in 2013 were estimated using resource use data from a chart review study (n = 122 with AGC) and national statistics. Annual per-patient costs, where patients' follow-up periods were adjusted for, were estimated with 82 patients who had complete resource use data. The costs were composed of direct medical costs, direct non-medical costs (healthcare travel and caregiver costs), morbidity costs, and mortality costs. Relevant unit costs were retrieved mainly from literature and national statistics, and applied to the resource use data. A broad definition of morbidity and mortality costs was employed to value the productivity loss in patients with unpaid employment, economically inactive and unemployed as well as the life years after the age of retirement. Their narrow definitions were also used in sensitivity analyses, using age- and/or sex-specific employment rates. Forgone future earnings/productivity loss were discounted at 3%. Annual per-patient costs were projected to estimate the total costs of AGC at the national level with an estimated number of patients with AGC (N = 2611) in Taiwan in 2013. The mean age of the 82 patients was 59.3 (SD: 11.9) years, and 67.1% were male. Per-patient costs were US$26,431 for direct medical costs, US$4669 for direct non-medical costs, US$5758 for morbidity costs, and US$145,990 for mortality costs (per death). These per-patient costs were projected to incur total AGC costs of US$423 million at the national-level. Mortality costs accounted for 77.3% of the total costs, followed by direct medical costs (16.3%), morbidity costs (3.6%), and direct non-medical costs (2.9%). AGC was found to exert a significant economic burden in Taiwan, incurring US$423 million in 2013. This represents about 0.08% of

  1. Phase-locked loops and their application

    NASA Technical Reports Server (NTRS)

    Lindsey, W. C. (Editor); Simon, M. K.

    1978-01-01

    A collection of papers is presented on the characteristics and capabilities of phase-locked loops (PLLs), along with some applications of interest. The discussion covers basic theory (linear and nonlinear); acquisition; threshold; stability; frequency demodulation and detection; tracking; cycle slipping and loss of lock; phase-locked oscillators; operation and performance in the presence of noise; AGC, AFC, and APC circuits and systems; digital PLL; and applications and miscellaneous. With the rapid development of IC technology, PLLs are expected to be used widely in consumer electronics.

  2. After the Biomedical Technology Revolution: Where to Now for a Bio-Psycho-Social Approach to Social Work?

    PubMed Central

    Healy, Karen

    2016-01-01

    In the late twentieth century, the bio-psycho-social framework emerged as a powerful influence on the conceptualisation and delivery of health and rehabilitation services including social work services in these fields. The bio-psycho-social framework is built on a systems view of health and well-being ( Garland and Howard, 2009). The systems perspective encourages medical and allied health professions, including social work, to recognise and to respond to the multiple systems impacting on individual health and well-being ( Engel, 2003). This paper analyses how advances in biomedical technology, particularly in the fields of neuroscience and human genomics, are challenging the bio-psycho-social approach to practice. The paper examines the pressures on the social work profession to embrace biomedical science and points to the problems in doing so. The conclusion points to some tentative ways forward for social workers to engage critically with biomedical advances and to strengthen the bio-psycho-social framework in the interests of holistic and ethical approaches to social work practice. PMID:27559237

  3. Testing and performance analysis of a 650-Mbps quaternary pulse position modulation (QPPM) modem for free-space laser communications

    NASA Astrophysics Data System (ADS)

    Mortensen, Dale J.

    1995-04-01

    The testing and performance of a prototype modem developed at NASA Lewis Research Center for high-speed free-space direct detection optical communications is described. The testing was performed under laboratory conditions using computer control with specially developed test equipment that simulates free-space link conditions. The modem employs quaternary pulse position modulation at 325 Megabits per second (Mbps) on two optical channels, which are multiplexed to transmit a single 650 Mbps data stream. The measured results indicate that the receiver's automatic gain control (AGC), phased-locked-loop slot clock recovery, digital symbol clock recovery, matched filtering, and maximum likelihood data recovery circuits were found to have only 1.5 dB combined implementation loss during bit-error-rate (BER) performance measurements. Pseudo random bit sequences and real-time high quality video sources were used to supply 650 Mbps and 325 Mbps data streams to the modem. Additional testing revealed that Doppler frequency shifting can be easily tracked by the receiver, that simulated pointing errors are readily compensated for by the AGC circuits, and that channel timing skew affects the BER performance in an expected manner. Overall, the needed technologies for a high-speed laser communications modem were demonstrated.

  4. Podcasting as Transformative Work

    ERIC Educational Resources Information Center

    Vasquez, Vivian Maria

    2015-01-01

    Although technology is most often heralded an intrinsic efficiency, the process of using technology to create a text is full of opportunities to learn new information, create and distribute knowledge, and engage in identity work. This article explores how the production of 1 such technological text, a podcast, offered students opportunities to…

  5. Hyaluronan-Based Therapy for Metastatic Prostate Cancer

    DTIC Science & Technology

    2015-07-01

    8217-AAG ACC CTT GTG CTC GTT GT-3’ and re- verse 5’-AGG TGG ACA CAA TCC CTC TG-3’ actin, forward 5’-TCC CTG GAG AAG AGC TAC GA-3’ and reverse 5’-AGC ACT... GTG TTG GCG TAC AG-3’. 2.2.5. Death-inducing signaling complex immunoprecipitation After HT-29 cells achieved 80% confluence, the cells were pretreated

  6. Genomic Instability and Breast Cancer

    DTIC Science & Technology

    2007-10-01

    transfected with control or RAP80 siRNAs were exposed to 0 or 4 grays (Gy) of IR. Cells were incubated for 1 hour before fixation and subjected to staining...similarly using primers 5’ AGA CAG AGC AAT CCA GTG AGT CTT TGA GGT GTA ACG TGG AGC CAG TAG 3’ and 5’ ACT GGC TCC ACG TTA CAC CTC AAA GAC TCA CTG GAT TGC

  7. Identification and Characterization of Ovarian Carcinoma Peptide Epitopes Recognized by Cylotoxic T Lymphocytes

    DTIC Science & Technology

    2008-11-01

    CTC CCA CAG TGC CCC AGG TTA GAA CGG TCA GCA GAA TAG-2a 62 528 AGC GGC GGG CTG AAG GA GAG GGT AGG GTG GTC ATT GTG TCA TAG-2b 62 401 AGC GGC GGG CTG AAG...64:388–393 66. Zhang L, Conejo-Garcia JR, Katsaros D, Gimotty PA, Massobrio M, Regnani G, Makrigiannakis A, Gray H, Schlienger K, Liebman MN, Rubin SC

  8. Role of Setbp1 in Myeloid Leukemia Development

    DTIC Science & Technology

    2014-09-05

    CTC ACT GTG GAG ACG ATT C 3’ 5’ TTC TTA TCC AGC ACA CCA AGC TT 3’ Hoxa9 5’ TGT CTC CTC TCC CCC AAA CC 3’ 5’ GAG ATG AGG CCT GGG ATTTAG A 3’ Hoxa10...highlighted in yellow and noncoding exons in gray . Arrows indicate transcription start sites. The location and orientation of viral integrations are

  9. Ultrathin Carbon Film Protected Silver Nanostructures for Surface-Enhanced Raman Scattering.

    PubMed

    Peng, Yinshan; Zheng, Xianliang; Tian, Hongwei; Cui, Xiaoqiang; Chen, Hong; Zheng, Weitao

    2016-06-23

    In this article, ultrathin carbon film protected silver substrate (Ag/C) was prepared via a plasma-enhanced chemical vapor deposition (PECVD) method. The morphological evolution of silver nanostructures underneath, as well as the surface-enhanced Raman scattering (SERS) activity of Ag/C hybrid can be tuned by controlling the deposition time. The stability and reproducibility of the as-prepared hybrid were also studied. © The Author(s) 2016.

  10. Health technology reassessment of non-drug technologies: current practices.

    PubMed

    Leggett, Laura; Noseworthy, Tom W; Zarrabi, Mahmood; Lorenzetti, Diane; Sutherland, Lloyd R; Clement, Fiona M

    2012-07-01

    Obsolescence is a natural phase of the lifecycle of health technologies. Given increasing cost of health expenditures worldwide, health organizations have little choice but to engage in health technology reassessment (HTR); a structured, evidence-based assessment of the medical, social, ethical, and economic effects of a technology, currently used within the healthcare system, to inform optimal use of that technology in comparison to its alternatives. This research was completed to identify and summarize international HTR initiatives for non-drug technologies. A systematic review was performed using the terms disinvestment, obsolescence, obsolete technology, ineffective, reassessment, reinvestment, reallocation, program budgeting, and marginal analysis to search PubMED, MEDLINE, EMBASE, and CINAHL until November 2011. Websites of organizations listed as members of INAHTA and HTAi were hand-searched for gray literature. Documents were excluded if they were unavailable in English, if the title/abstract was irrelevant to HTR, and/or if the document made no mention of current practices. All citations were screened in duplicate with disagreements resolved by consensus. Sixty full-text documents were reviewed and forty were included. One model for reassessment was identified; however, it has never been put into practice. Eight countries have some evidence of past or current work related to reassessment; seven have shown evidence of continued work in HTR. There is negligible focus on monitoring and implementation. HTR is in its infancy. Although health technology reassessments are being conducted, there is no standardized approach. Future work should focus on developing and piloting a comprehensive methodology for completing HTR.

  11. Emerging Communication Technologies (ECT) Phase 2 Report. Volume 3; Ultra Wideband (UWB) Technology

    NASA Technical Reports Server (NTRS)

    Bastin, Gary L.; Harris, William G.; Chiodini, Robert; Nelson, Richard A.; Huang, PoTien; Kruhm, David A.

    2003-01-01

    The Emerging Communication Technology (ECT) project investigated three First Mile communication technologies in support of NASA s Second Generation Reusable Launch Vehicle (2nd Gen RLV), Orbital Space Plane, Advanced Range Technology Working Group (ARTWG) and the Advanced Spaceport Technology Working Group (ASTWG). These First Mile technologies have the purpose of interconnecting mobile users with existing Range Communication infrastructures. ECT was a continuation of the Range Information System Management (RISM) task started in 2002. RISM identified the three advance communication technologies investigated under ECT. These were Wireless Ethernet (Wi-Fi), Free Space Optics (FSO), and Ultra Wideband (UWB). Due to the report s size, it has been broken into three volumes: 1) Main Report 2) Appendices 3) UWB

  12. Partners in Technology

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Deere and Company scientists are working with various NASA centers in a multifaceted technical exchange program investigating areas of aerospace technology that can be applied to company's products. This is a non-traditional type spinoff in that it does not simply reapply existing technology but development of new technology using Deere's extensive R & D capability to complement NASA's efforts, adapting NASA information to new research paths and providing feedback of importance to NASA's own work. NASA/Deere exchange extends to these areas: Composite materials, ceramics, wear and lubrication, plasma coatings and sensors, and electronics.

  13. Strategic avionics technology planning

    NASA Technical Reports Server (NTRS)

    Cox, Kenneth J.; Brown, Don C.

    1991-01-01

    NASA experience in development and insertion of technology into programs had led to a recognition that a Strategic Plan for Avionics is needed for space. In the fall of 1989 an Avionics Technology Symposium was held in Williamsburg, Virginia. In early 1990, as a followon, a NASA wide Strategic Avionics Technology Working Group was chartered by NASA Headquarters. This paper will describe the objectives of this working group, technology bridging, and approaches to incentivize both the federal and commercial sectors to move toward rapidly developed, simple, and reliable systems with low life cycle cost.

  14. Making aerospace technology work for the automotive industry, introduction

    NASA Technical Reports Server (NTRS)

    Olson, W. T.

    1978-01-01

    NASA derived technology already in use in the automotive industry include: (1) developments in electronics design, computer systems, and quality control methods for line testing of cars and trucks; (2) a combustion analysis computer program for automotive engine research and development; (3) an infrared scanner and television display for analyzing tire design and performance, and for studying the effects of heat on the service life of V-belts, shock mounts, brakes, and rubber bearings; (4) exhaust gas analyzers for trouble shooting and emissions certification; (5) a device for reducing noise from trucks; and (6) a low cost test vehicle for measuring highway skid resistance. Services offered by NASA to facilitate access to its technology are described.

  15. Cost-effectiveness Analysis of Fluorouracil, Leucovorin, and Irinotecan versus Epirubicin, Cisplatin, and Capecitabine in Patients with Advanced Gastric Adenocarcinoma

    PubMed Central

    Wen, Feng; Zheng, Hanrui; Wu, Yifan; Wheeler, John; Zeng, Xiaoxi; Fu, Ping; Li, Qiu

    2016-01-01

    No standard treatment has been accepted widely for the first-/second-line therapy for advanced gastric cancer (AGC). The current study aimed to determine a preferred strategy between FOLFIRI (fluorouracil, leucovorin, and irinotecan) and ECX (epirubicin, cisplatin,and capecitabine) for AGC from the cost-effectiveness perspective. According to a French intergroup study, two groups (ECX arm and FOLFIRI arm) and three health states (progression-free survival (PFS), progressive disease (PD) and death) were analyzed in the current Markov model. All the medical costs were calculated from a Chinese societal perspective. Although FOLFIRI was an acceptable first-line therapy in the treatment of AGC with a better time-to treatment failure (TTF) compared to ECX, ECX arm (ECX followed by FOLFIRI) gained 0.08 quality-adjusted life months (QALMs) more effectiveness benefit compared with FOLFIRI arm (FOLFIRI followed by ECX). Additionally, a lower cost was found in ECX arm ($23,813.13 versus $24,983.70). Hence, the strategy of FOLFIRI arm is dominated by ECX arm ($4,125.8 per QALM in FOLIRI arm; $3,879.724 per QALM in ECX arm). ECX followed by FOLFIRI was a preferred strategy with more effectiveness and lower cost compared with FOLFIRI followed by ECX for the treatment of AGC. PMID:27824060

  16. The Complete Picture: "Standards for Technological Literacy" and "Advancing Excellence in Technological Literacy."

    ERIC Educational Resources Information Center

    Technology Teacher, 2003

    2003-01-01

    Provides an overview of the "Standards for Technological Literacy: Content for the Study of Technology" (STL) and "Advancing Excellence in Technological Literacy: Student Assessment, Professional Development, and Program Standards" (AETL). Shows how the documents work together to advance the technological literacy of technology educators and K-12…

  17. Sandia National Laboratories: Working with Sandia

    Science.gov Websites

    Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios Report Economic Impact Environmental Reports Fact Sheets Search Sandia Publications Labs Accomplishments /Technology Transfer Technology Partnerships Economic Impact Facebook Twitter YouTube Flickr RSS Working with

  18. Patient source of learning about health technologies and ratings of trust in technologies used in their care

    PubMed Central

    Montague, Enid

    2011-01-01

    In order to design effective health technologies and systems, it is important to understand how patients learn and make decisions about health technologies used in their care. The objective of this study was to examine patients' source of learning about technologies used in their care and how the source related to their trust in the technology used. Individual face-to-face and telephone interviews were conducted with 24 patients. Thirteen unique sources of information about technology were identified and three major themes emerged; outside of the work system versus inside the work system, when the health information was provided, and the medium used. Patients used multiple sources outside of the health care work system to learn about technologies that will be used in their care. Results showed a relationship between learning about technologies from web sources and trust in technologies but no relationship between learning about technologies from health care providers and trust in technologies. PMID:20967654

  19. Beyond technology acceptance to effective technology use: a parsimonious and actionable model.

    PubMed

    Holahan, Patricia J; Lesselroth, Blake J; Adams, Kathleen; Wang, Kai; Church, Victoria

    2015-05-01

    To develop and test a parsimonious and actionable model of effective technology use (ETU). Cross-sectional survey of primary care providers (n = 53) in a large integrated health care organization that recently implemented new medication reconciliation technology. Surveys assessed 5 technology-related perceptions (compatibility with work values, implementation climate, compatibility with work processes, perceived usefulness, and ease of use) and 1 outcome variable, ETU. ETU was measured as both consistency and quality of technology use. Compatibility with work values and implementation climate were found to have differential effects on consistency and quality of use. When implementation climate was strong, consistency of technology use was high. However, quality of technology use was high only when implementation climate was strong and values compatibility was high. This is an important finding and highlights the importance of users' workplace values as a key determinant of quality of use. To extend our effectiveness in implementing new health care information technology, we need parsimonious models that include actionable determinants of ETU and account for the differential effects of these determinants on the multiple dimensions of ETU. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  20. NPY genes play an essential role in root gravitropic responses in Arabidopsis.

    PubMed

    Li, Yuanting; Dai, Xinhua; Cheng, Youfa; Zhao, Yunde

    2011-01-01

    Plants can sense the direction of gravity and orient their growth to ensure that roots are anchored in soil and that shoots grow upward. Gravitropism has been studied extensively using Arabidopsis genetics, but the exact mechanisms for gravitropism are not fully understood. Here, we demonstrate that five NPY genes play a key role in Arabidopsis root gravitropism. NPY genes were previously identified as regulators of auxin-mediated organogenesis in a genetic pathway with the AGC kinases PID, PID2, WAG1, and WAG2. We show that all five NPY genes are highly expressed in primary root tips. The single npy mutants do not display obvious gravitropism defects, but the npy1 npy2 npy3 npy4 npy5 quintuple mutants show dramatic gravitropic phenotypes. Systematic analysis of all the npy double, triple, and quadruple combinations demonstrates that the five NPY genes all contribute to gravitropism. Our work indicates that gravitropism, phototropism, and organogenesis use analogous mechanisms in which at least one AGC kinase, one NPH3/NPY gene, and one ARF are required.

  1. Work of the cosmonaut

    NASA Technical Reports Server (NTRS)

    Demin, L. S.

    1980-01-01

    The necessity for the cosmonaut to receive broad training in many fields in order to carry out his multifaceted work is discussed. The work includes: scientific research, engineering, operator's work, participation in technical commissions and councils, training on simulators, and the study of technology and sports.

  2. UNIVERSITY RESEARCH PROGRAMS IN ROBOTICS, TECHNOLOGIES FOR MICROELECTROMECHANICAL SYSTEMS IN DIRECTED STOCKPILE WORK RADIATION AND ENGINEERING CAMPAIGNS - 2005-06 FINAL ANNUAL REPORT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    James S. Tulenko; Dean Schoenfeld; David Hintenlang

    The research performed by the University of Florida (UF) is directed to the development of technologies that can be utilized at a micro-scale in varied environments. Work is focused on micro-scale energy systems, visualization, and mechanical devices. This work will impact the NNSA need related to micro-assembly operations. The URPR activities are executed in a University environment, yet many applications of the resulting technologies may be classified or highly restrictive in nature. The NNSA robotics technologists apply an NNSA needs focus to the URPR research, and actively work to transition relevant research into the deployment projects in which they aremore » involved. This provides a “Research to Development to Application” structure within which innovative research has maximum opportunity for impact without requiring URPR researchers to be involved in specific NNSA projects. URPR researchers need to be aware of the NNSA applications in order to ensure the research being conducted has relevance, the URPR shall rely upon the NNSA sites for direction.« less

  3. Employee Participation, Work Redesign, and New Technology: Implications for Public Policy in the 1990s. Background Paper No. 35A.

    ERIC Educational Resources Information Center

    Kochan, Thomas; And Others

    The 1980s have been a period during which important private experiments with innovations have occurred in employee participation, work redesign, and the introduction of new technologies and new systems of production. It is now time to move beyond the experimental stage. The following four interrelated policy initiatives should guide public efforts…

  4. Teaching with Technology

    ERIC Educational Resources Information Center

    Attard, Catherine

    2011-01-01

    New technologies continue to change every aspect of home, life and work: the way people communicate, calculate, analyse, shop, make presentations and socialise. "The Australian Curriculum" acknowledges the importance of teaching and learning with technology by including the use of information and communication technology (ICT) as one of…

  5. Electrical System Technology Working Group (WG) Report

    NASA Technical Reports Server (NTRS)

    Silverman, S.; Ford, F. E.

    1984-01-01

    The technology needs for space power systems (military, public, commercial) were assessed for the period 1995 to 2005 in the area of power management and distribution, components, circuits, subsystems, controls and autonomy, modeling and simulation. There was general agreement that the military requirements for pulse power would be the dominant factor in the growth of power systems. However, the growth of conventional power to the 100 to 250kw range would be in the public sector, with low Earth orbit needs being the driver toward large 100kw systems. An overall philosophy for large power system development is also described.

  6. Does Technology Acceptance Affect E-Learning in a Non-Technology-Intensive Course?

    ERIC Educational Resources Information Center

    Buche, Mari W.; Davis, Larry R.; Vician, Chelley

    2012-01-01

    Prior research suggests that individuals' technology acceptance levels may affect their work and learning performance outcomes when activities are conducted through information technology usage. Most previous research investigating the relationship between individual attitudes towards technology and learning has been conducted in…

  7. Work stress and oral health-related quality of life among Indian information technology workers: an exploratory study.

    PubMed

    Acharya, Shashidhar; Pentapati, Kalyana C

    2012-06-01

    To assess the relationships among work stress, oral health and oral health-related quality of life (OHRQoL) in information technology (IT) professionals in south India. The study population consisted of 134 IT industry workers in four mid-size IT companies in south India. A self-administered questionnaire consisting of the eight-item Oral Impact on Daily Performance (OIDP) scale and a 25-item modified version of the original 167-item Work Stress Questionnaire was given, following which an oral examination was carried out. Mean ± standard deviation scores on the Work Stress Questionnaire, the decayed, missing and filled teeth (DMFT) index and the Community Periodontal Index of Treatment Needs (CPITN) for the sample population were 53.82 ± 15.07, 4.23 ± 3.47 and 1.81 ± 0.58, respectively. A comparison of clinical oral health status data against respondents' work stress and OIDP scores showed that mean DMFT and CPITN scores were significantly greater among those who reported oral impact on their daily performance. However, although participants who reported oral problems had consistently higher work stress scores, the differences were statistically significant only for gingival bleeding and sensitive teeth. Multivariate analysis after controlling for age and sex showed that higher levels of work stress and periodontal disease were significant predictors for poor OHRQoL in the sample population.  Work stress may be an important predictor for poor OHRQoL and hence requires to be studied in greater detail. © 2012 FDI World Dental Federation.

  8. Partitionable-space enhanced coagulation (PEC) reactor and its working mechanism: a new prospective chemical technology for phosphorus pollution control.

    PubMed

    Zhang, Meng; Zheng, Ping; Abbas, Ghulam; Chen, Xiaoguang

    2014-02-01

    Phosphorus pollution control and phosphorus recycling, simultaneously, are focus of attention in the wastewater treatment. In this work, a novel reactor named partitionable-space enhanced coagulation (PEC) was invented for phosphorus control. The working performance and process mechanism of PEC reactor were investigated. The results showed that the PEC technology was highly efficient and cost-effective. The volumetric removal rate (VRR) reached up to 2.86 ± 0.04 kg P/(m(3) d) with a phosphorus removal rate of over 97%. The precipitant consumption was reduced to 2.60-2.76 kg Fe(II)/kg P with low operational cost of $ 0.632-0.673/kg P. The peak phosphorus content in precipitate was up to 30.44% by P2O5, which reveal the benefit of the recycling phosphorus resource. The excellent performance of PEC technology was mainly attributed to the partitionable-space and 'flocculation filter'. The partition limited the trans-regional back-mixing of reagents along the reactor, which promoted the precipitation reaction. The 'flocculation filter' retained the microflocs, enhancing the flocculation process. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Working conditions and health among employees at information technology--enabled services: a review of current evidence.

    PubMed

    Kesavachandran, C; Rastogi, S K; Das, Mohan; Khan, Asif M

    2006-07-01

    Workers in information technology (IT)-enabled services like business process outsourcing and call centers working with visual display units are reported to have various health and psycho-social disorders. Evidence from previously published studies in peer- reviewed journals and internet sources were examined to explore health disorders and psycho-social problems among personnel employed in IT-based services, for a systematic review on the topic. In addition, authors executed a questionnaire- based pilot study. The available literature and the pilot study, both suggest health disorders and psychosocial problems among workers of business process outsourcing. The details are discussed in the review.

  10. Industrial Technology Education Teachers' Knowledge, Experience, and Feelings Related To Working with Special Population Students in the Lincoln, Nebraska Public Schools.

    ERIC Educational Resources Information Center

    Howell, Robert T.

    2000-01-01

    Survey responses from 20 of 39 industrial technology education teachers in Lincoln, Nebraska, indicated that they felt able to teach special needs students but desired more training. They did not receive adequate support for working with these students and preferred professional days for inservice training. (SK)

  11. Functional Pathways of Social Support for Mental Health in Work and Family Domains Among Chinese Scientific and Technological Professionals.

    PubMed

    Gan, Yiqun; Gan, Tingting; Chen, Zhiyan; Miao, Miao; Zhang, Kan

    2015-10-01

    This study investigated the role of social support in the complex pattern of associations among stressors, work-family interferences and depression in the domains of work and family. A questionnaire was administered to a nationwide sample of 11,419 Chinese science and technology professionals. Several structural equation models were specified to determine whether social support functioned as a predictor or a mediator. Using Mplus 5.0, we compared the moderation model, the independence model, the antecedent model and the mediation model. The results revealed that the relationship between work-family interference and social support was domain specific. The independence model fit the data best in the work domain. Both the moderation model and the antecedent model fit the family domain data equally well. The current study was conducted to answer the need for comprehensive investigations of cultural uniqueness in the antecedents of work-family interference. The domain specificity, i.e. the multiple channels of the functions of support in the family domain and not in the work domain, ensures that this study is unique and culturally specific. Copyright © 2014 John Wiley & Sons, Ltd.

  12. Technology Toolkit.

    ERIC Educational Resources Information Center

    Brooklyn Public Library, NY.

    This reference resource identifies issues concerning technology use in library literacy programs and describes approaches that work at the Brooklyn (New York) Public Library. Section 1 discusses the learning centers at the library, including its mission, philosophy, curriculum, technology, volunteer tutors, and active learning environment. Section…

  13. Workshop on Science and Technology Education and Productive Work. Final Report.

    ERIC Educational Resources Information Center

    Ministry of Education, Addis Ababa (Ethiopia).

    This workshop was organized as a contribution to Ethiopia's human resettlement activities necessitated by the recurrent drought. The objectives of the workshop were to: (1) appraise the relevance of basic rural technologies and identify modalities of their application; (2) develop materials in the fields of biotechnology and basic technology; (3)…

  14. Technology Use and Mathematics Teaching: Teacher Change as Discursive Identity Work

    ERIC Educational Resources Information Center

    Chronaki, Anna; Matos, Anastasios

    2014-01-01

    Teacher change towards developing competences for technology use in mathematics teaching has been the focus of current educational reforms worldwide. However, a considerable amount of research denotes the extent to which teachers resist a full integration of technology in mathematics classrooms. The present paper is based on an ethnographic study…

  15. The Effect of Technology on Alienation from Work. Testing Blauner's Inverted U-Curve Hypothesis for 110 Industrial Organizations and 245 Retrained Printers.

    ERIC Educational Resources Information Center

    Hull, Frank M.; And Others

    1982-01-01

    Presents new evidence on the effect of technology on worker alienation, using data from the organizational level as well as the individual level. In the latter approach, the impact of automation on the work of newspaper printers is examined. (SK)

  16. "Apping Up": Prospects for Information Technology Innovation in Return to Work Communication.

    PubMed

    Singh, Ripdaman; O'Hagan, Fergal

    2018-03-21

    Purpose During return to work (RTW), communication between health care providers and employers largely takes place through standardize paper-based forms. Information technology (IT) platforms may provide advantages in enabling information exchange and decision-making through sharing of guidelines and resources. We investigated stakeholder perspectives on the prospect of IT use for RTW communication in Ontario, Canada. Methods Consistent with the exploratory nature of the questions, qualitative methods were used. Primary data were interviews with health care providers (HCPs), employers, and workers with experience in RTW. The first portion of initial interviews elicited general perspectives and experiences related to RTW communication. Participants were then exposed to a prototype IT communication platform and elicited their feedback. Follow-up interviews with HCP's and EMP's were used to allow further reflection and clarification of data. We used progressive, thematic coding to analyze data. Results 12 HCPs, 7 employers, and 5 workers participated in the study. Five inter-related themes were obtained. Participants expressed no absolute objection to the use of IT for RTW communication but varying degrees of support. Participants revealed how media change depended on a prospective IT innovation's perceived usefulness, fit with current practices, capacity to gain buy-in from other stakeholders, and ability to demonstrate positive performance in actual practice. Conclusions Findings suggest that a transition to an IT-mediated tool for RTW communication is supported in principle; however, major caveats exist in relation to perceived value and fit with stakeholder practice. System support and stakeholder cooperation are likely necessary to adopt the change, yet IT-mediated communication has yet to demonstrate value. To avoid circularity, proof of principal needs to be established through an implementation trial of such technology.

  17. Funding of Assistive Technology to Make Work a Reality, Part II: Using the Americans with Disabilities Act to Fund AT. Policy & Practice Brief #13

    ERIC Educational Resources Information Center

    Hager, Ronald M.

    2004-01-01

    This is a continuation of "Funding of Assistive Technology to Make Work a Reality" (Work and AT), Article # 3 in this Policy and Practice Brief Series. This article will review the provisions of the Americans with Disabilities Act (ADA), with a particular emphasis on how the ADA can be used to ensure that a person with a disability has…

  18. Older Adults Talk Technology: Technology Usage and Attitudes.

    PubMed

    Mitzner, Tracy L; Boron, Julie B; Fausset, Cara Bailey; Adams, Anne E; Charness, Neil; Czaja, Sara J; Dijkstra, Katinka; Fisk, Arthur D; Rogers, Wendy A; Sharit, Joseph

    2010-11-01

    Older adults (n = 113) participated in focus groups discussing their use of and attitudes about technology in the context of their home, work, and healthcare. Participants reported using a wide variety of technology items, particularly in their homes. Positive attitudes (i.e., likes) outnumbered negative attitudes (i.e., dislikes), suggesting that older adults perceive the benefits of technology use to outweigh the costs of such use. Positive attitudes were most frequently related to how the technology supported activities, enhanced convenience, and contained useful features. Negative attitudes were most frequently associated with technology creating inconveniences, unhelpful features, as well as security and reliability concerns. Given that older adults reported more positive than negative attitudes about the technologies they use, these results contradict stereotypes that older adults are afraid or unwilling to use technology. These findings also highlight the importance of perceived benefits of use and ease of use for models of technology acceptance. Emphasizing the benefits of technology in education and training programs may increase future technology adoption.

  19. Overexpression of cinnamate 4-hydroxylase gene enhances biosynthesis of decursinol angelate in Angelica gigas hairy roots.

    PubMed

    Park, Nam Il; Park, Jee Hee; Park, Sang Un

    2012-02-01

    Angelica gigas is a medicinal plant that produces pyranocoumarins, including decursin (D) and decursinol angelate (DA), which have neuroprotective, anticancer, and antiandrogenic effects. In this study, the coumarin biosynthetic pathway was engineered to increase the production of DA. Specifically, a vector was constructed which contained the A. gigas phenylalanine ammonia-lyase (AgPAL) and cinnamate 4-hydroxylase (AgC4H) genes that were driven by the cauliflower mosaic virus (CaMV) 35S promoter. Transgenic hairy roots that overexpressed AgPAL or AgC4H genes were obtained by using an Agrobacterium rhizogenes-mediated transformation system. Among them, only AgC4H-transgenic hairy root lines produced more DA than control transgenic hairy root lines. The enhanced gene expression corresponded to elevated C4H activities. This study showed the importance of C4H in the production of DA in A. gigas hairy root culture.

  20. Toward Technology Integration in Mathematics Education: A Technology-Integration Course Planning Assignment

    ERIC Educational Resources Information Center

    Kersaint, Gladis

    2007-01-01

    This article describes a technology integration course planning assignment that was developed to enhance preservice teachers' technological pedagogical content knowledge (TPCK). This assignment required preservice teachers work with peers to integrate various technological tools (e.g., graphing calculators, web-based mathematics applets, etc) in a…

  1. Preoperative administration of polysaccharide Kureha and reduced plasma transforming growth factor-β in patients with advanced gastric cancer: A randomized clinical trial

    PubMed Central

    YAMASHITA, KEISHI; SAKURAMOTO, SHINICHI; MIENO, HIROAKI; NEMOTO, MASAYUKI; SHIBATA, TOMOTAKA; KATADA, NATSUYA; OHTSUKI, SHIGEAKI; SAKAMOTO, YASUTOSHI; HOSHI, KEIKA; WANG, GUOQIN; HEMMI, OSAMU; SATOH, TOSHIHIKO; KIKUCHI, SHIRO; WATANABE, MASAHIKO

    2015-01-01

    Systemic abrogation of TGF-β signaling results in tumor reduction through cytotoxic T lymphocytes activity in a mouse model. The administration of polysaccharide-Kureha (PSK) into tumor-bearing mice also showed tumor regression with reduced TGF-β. However, there have been no studies regarding the PSK administration to cancer patients and the association with plasma TGF-β. PSK (3 g/day) was administered as a neoadjuvant therapy for 2 weeks before surgery. In total, 31 advanced gastric cancer (AGC) patients were randomly assigned to group A (no neoadjuvant PSK; n=14) or B (neoadjuvant PSK therapy; n=17). Plasma TGF-β was measured pre- and postoperatively. The allocation factors were clinical stage (cStage) and gender. Plasma TGF-β ranged from 1.85–43.5 ng/ml (average, 9.50 ng/ml) in AGC, and 12 patients (38.7%) had a high value, >7.0 ng/ml. These patients were largely composed of poorly-differentiated adenocarcinoma with pathological stage III/IV. All the six elevated cases in group B showed a significant reduction of plasma TGF-β (from 21.6 to 4.5 ng/ml, on average), whereas this was not exhibited in group A. The cases within the normal limits of TGF-β remained unchanged irrespective of PSK treatment. Analysis of variance showed a statistically significant reduction in the difference of plasma TGF-β between groups A and B (P=0.019). PSK reduced the plasma TGF-β in AGC patients when the levels were initially high. The clinical advantage of PSK may, however, be restricted to specific histological types of AGC. Perioperative suppression of TGF-β by PSK may antagonize cancer immune evasion and improve patient prognosis in cases of AGC. PMID:26137253

  2. Predictors of Team Work Satisfaction

    ERIC Educational Resources Information Center

    Hamlyn-Harris, James H.; Hurst, Barbara J.; von Baggo, Karola; Bayley, Anthony J.

    2006-01-01

    The ability to work in teams is an attribute highly valued by employers of information technology (IT) graduates. For IT students to effectively engage in team work tasks, the process of working in teams should be satisfying for the students. This work explored whether university students who were involved in compulsory team work were satisfied…

  3. Active Work Zone Safety Using Emerging Technologies : Final Report

    DOT National Transportation Integrated Search

    2017-07-01

    The major objectives of this research were to (1) identify technologies that can be used in real time to detect a hazardous proximity situation between construction equipment and pedestrian workers and provide an appropriate warning; (2) develop a Bl...

  4. Protecting Defense Technologies: DOD Assessment Needed to Determine Requirement for Critical Technologies List

    DTIC Science & Technology

    2013-01-01

    Service DTSA Defense Technology Security Administration MCTL Militarily Critical Technologies List This is a work of the U.S. government and is not...Respond to MCTL Weaknesses Page 8 GAO-13-157 Protecting Defense Technologies Administration ( DTSA ), military services, and DOD...implementation of technology security policies on international transfers of defense- related goods, services, and technologies; • directed DTSA to

  5. Comparison of RECIST version 1.0 and 1.1 in assessment of tumor response by computed tomography in advanced gastric cancer.

    PubMed

    Jang, Gil-Su; Kim, Min-Jeong; Ha, Hong-Il; Kim, Jung Han; Kim, Hyeong Su; Ju, Sung Bae; Zang, Dae Young

    2013-12-01

    Response Evaluation Criteria in Solid Tumors (RECIST) guideline version 1.0 (RECIST 1.0) was proposed as a new guideline for evaluating tumor response and has been widely accepted as a standardized measure. With a number of issues being raised on RECIST 1.0, however, a revised RECIST guideline version 1.1 (RECIST 1.1) was proposed by the RECIST Working Group in 2009. This study was conducted to compare CT tumor response based on RECIST 1.1 vs. RECIST 1.0 in patients with advanced gastric cancer (AGC). We reviewed 61 AGC patients with measurable diseases by RECIST 1.0 who were enrolled in other clinical trials between 2008 and 2010. These patients were retrospectively re-analyzed to determine the concordance between the two response criteria using the κ statistic. The number and sum of tumor diameters of the target lesions by RECIST 1.1 were significantly lower than those by RECIST 1.0 (P<0.0001). However, there was excellent agreement in tumor response between RECIST 1.1 and RECIST 1.0 (κ=0.844). The overall response rates (ORRs) according to RECIST 1.0 and RECIST 1.1 were 32.7% (20/61) and 34.5% (20/58), respectively. One patient with partial response (PR) based on RECIST 1.0 was reclassified as stable disease (SD) by RECIST 1.1. Of two patients with SD by RECIST 1.0, one was downgraded to progressive disease and the other was upgraded to PR by RECIST 1.1. RECIST 1.1 provided almost perfect agreement with RECIST 1.0 in the CT assessment of tumor response of AGC.

  6. Low levels of citrin (SLC25A13) expression in adult mouse brain restricted to neuronal clusters.

    PubMed

    Contreras, Laura; Urbieta, Almudena; Kobayashi, Keiko; Saheki, Takeyori; Satrústegui, Jorgina

    2010-04-01

    The mitochondrial aspartate-glutamate carriers (AGC) aralar (SLC25A12) and citrin (SLC25A13) are components of the malate aspartate shuttle (MAS), a major intracellular pathway to transfer reducing equivalents from NADH to the mitochondrial matrix. Aralar is the main AGC isoform present in the adult brain, and it is expressed mainly in neurons. To search for the other AGC isoform, citrin, in brain glial cells, we used a citrin knockout mouse in which the lacZ gene was inserted into the citrin locus as reporter gene. In agreement with the low citrin levels known to be present in the adult mouse brain, beta-galactosidase expression was very low. Surprisingly, unlike the case with astroglial cultures that express citrin, no beta-galactosidase was found in brain glial cells. It was confined to neuronal cells within discrete neuronal clusters. Double-immunolabelling experiments showed that beta-galactosidase colocalized not with glial cell markers but with the pan-neuronal marker NeuN. The deep cerebellar nuclei and a few midbrain nuclei (reticular tegmental pontine nuclei; magnocellular red nuclei) were the regions where beta-galactosidase expression was highest, and it was up-regulated in fasted mice, as was also the case for liver beta-galactosidase. The results support the notion that glial cells have much lower AGC levels and MAS activity than neurons. (c) 2009 Wiley-Liss, Inc.

  7. Evaluation of a method for enhancing interaural level differences at low frequencies.

    PubMed

    Moore, Brian C J; Kolarik, Andrew; Stone, Michael A; Lee, Young-Woo

    2016-10-01

    A method (called binaural enhancement) for enhancing interaural level differences at low frequencies, based on estimates of interaural time differences, was developed and evaluated. Five conditions were compared, all using simulated hearing-aid processing: (1) Linear amplification with frequency-response shaping; (2) binaural enhancement combined with linear amplification and frequency-response shaping; (3) slow-acting four-channel amplitude compression with independent compression at the two ears (AGC4CH); (4) binaural enhancement combined with four-channel compression (BE-AGC4CH); and (5) four-channel compression but with the compression gains synchronized across ears. Ten hearing-impaired listeners were tested, and gains and compression ratios for each listener were set to match targets prescribed by the CAM2 fitting method. Stimuli were presented via headphones, using virtualization methods to simulate listening in a moderately reverberant room. The intelligibility of speech at ±60° azimuth in the presence of competing speech on the opposite side of the head at ±60° azimuth was not affected by the binaural enhancement processing. Sound localization was significantly better for condition BE-AGC4CH than for condition AGC4CH for a sentence, but not for broadband noise, lowpass noise, or lowpass amplitude-modulated noise. The results suggest that the binaural enhancement processing can improve localization for sounds with distinct envelope fluctuations.

  8. Ecological Risk Assessment of Munitions Compounds on Coral and Coral Reef Health

    DTIC Science & Technology

    2014-01-01

    C308R Porites lobata Maunalua Bay, Oahu, HI K5 TAG GTG GGG AAT CAA ACG GC C307F C309F Porites lobata La Perouse, Maui, HI 3-3 GCT GGC TTA CAG...GGA ATT TTA ACT TCA AGC 24 41.7% 54°C 2.08 Kb this work Porites mtDNA cobR A GAT TCT CTT TGC GCA GTG GCA TAG G 25 52.0% 59°C this work Porites mtDNA...47.6% 52°C 2.14 Kb this work Porites mtDNA nad5(5’)R K CCA ACT GTG CAG ACT TTC CAA CC 23 52.2% 57°C this work References and further reading

  9. Status of Laser/Lidar Working Group Requirements

    NASA Technical Reports Server (NTRS)

    Kavaya, Michael J.; Gentry, Bruce M.

    2006-01-01

    This viewgraph presentation reviews the status of the development of the requirements by the Laser/Lidar working group. Included in the presentation is another viewgraph report on the NASA Earth Science Technology Office (ESTO) Laser/Lidar working group, by the chairperson of the working group. Some of the uses of Laser and Lidar in earth sciences are reviewed and a roadmap for the future use of the technology is included.

  10. Working alone.

    PubMed

    Tearle, Paul

    2004-09-01

    Employees may be found working alone in a wide range of occupations. Technological advance, rationalisation and automation mean that more and more frequently. one single person is in charge of several machines, pieces of equipment or different work activities. Employees will be found working alone during work carried out as 'overtime', as part of flexible working hours, on Saturdays, Sundays, Bank Holidays and other statutory leave days, or in situations where their work takes them away from a fixed base (mobile workers). A person may be considered to be 'working alone' whenever it is not possible to offer immediate assistance following an accident or in another critical situation. This article looks at the legal background to lone working and what an employer must do to ensure lone workers are at no greater risk to their health and safety than any other members of the workforce.

  11. Technology and Student Affairs: Redux

    ERIC Educational Resources Information Center

    Moneta, Larry

    2005-01-01

    The author addresses two critical questions related to technology: How has students' use of technology influenced student affairs work? How do we best align our business practices with advances in information technology?

  12. Older Adults Talk Technology: Technology Usage and Attitudes

    PubMed Central

    Mitzner, Tracy L.; Boron, Julie B.; Fausset, Cara Bailey; Adams, Anne E.; Charness, Neil; Czaja, Sara J.; Dijkstra, Katinka; Fisk, Arthur D.; Rogers, Wendy A.; Sharit, Joseph

    2010-01-01

    Older adults (n = 113) participated in focus groups discussing their use of and attitudes about technology in the context of their home, work, and healthcare. Participants reported using a wide variety of technology items, particularly in their homes. Positive attitudes (i.e., likes) outnumbered negative attitudes (i.e., dislikes), suggesting that older adults perceive the benefits of technology use to outweigh the costs of such use. Positive attitudes were most frequently related to how the technology supported activities, enhanced convenience, and contained useful features. Negative attitudes were most frequently associated with technology creating inconveniences, unhelpful features, as well as security and reliability concerns. Given that older adults reported more positive than negative attitudes about the technologies they use, these results contradict stereotypes that older adults are afraid or unwilling to use technology. These findings also highlight the importance of perceived benefits of use and ease of use for models of technology acceptance. Emphasizing the benefits of technology in education and training programs may increase future technology adoption. PMID:20967133

  13. Testing and performance analysis of a 650 Mbps QPPM modem for free-space laser communications

    NASA Astrophysics Data System (ADS)

    Mortensen, Dale J.

    1994-08-01

    The testing and performance of a prototype modem developed at NASA Lewis Research Center for high-speed free-space direct detection optical communications is described. The testing was performed under laboratory conditions using computer control with specially developed test equipment that simulates free-space link conditions. The modem employs quaternary pulse position modulation (QPPM) at 325 Megabits per second (Mbps) on two optical channels, which are multiplexed to transmit a single 650 Mbps data stream. The measured results indicate that the receiver's automatic gain control (AGC), phased-locked-loop slot clock recovery, digital symbol clock recovery, matched filtering, and maximum likelihood data recovery circuits were found to have only 1.5 dB combined implementation loss during bit-error-rate (BER) performance measurements. Pseudo random bit sequences and real-time high quality video sources were used to supply 650 Mbps and 325 Mbps data streams to the modem. Additional testing revealed that Doppler frequency shifting can be easily tracked by the receiver, that simulated pointing errors are readily compensated for by the AGC circuits, and that channel timing skew affects the BER performance in an expected manner. Overall, the needed technologies for a high-speed laser communications modem were demonstrated.

  14. Technology Push

    ERIC Educational Resources Information Center

    Kennedy, Mike

    2008-01-01

    When students, teachers, administrators and others employed in education arrive at work every day on thousands of campuses across the nation, it should come as no surprise that at every step along the way, technology is there to greet them. Technological advancements in education, as well as in facilities operation and management, are not a…

  15. Telemedia Technology. Telecommunications Study Commission, Working Paper No. 5.

    ERIC Educational Resources Information Center

    Fairholm, Gilbert W.

    This report presents an overview of the distribution formats for instructional television. While broadcast means of distribution have ben the mainstay of instructional television in the past, there are at least three television technologies that are considered as appropriate delivery mechanisms: over the air transmission, including broadcasting,…

  16. Making Technology Work for Scholarship: Investing in the Data.

    ERIC Educational Resources Information Center

    Hockey, Susan

    This paper examines issues related to how providers and consumers can make the best use of electronic information, focusing on the humanities. Topics include: new technology or old; electronic text and data formats; Standard Generalized Markup Language (SGML); text encoding initiative; encoded archival description (EAD); other applications of…

  17. Effect of autologous platelet-rich plasma on the chondrogenic differentiation of rabbit adipose-derived stem cells in vitro

    PubMed Central

    TANG, XIAO-BO; DONG, PEI-LONG; WANG, JIAN; ZHOU, HAI-YANG; ZHANG, HAI-XIANG; WANG, SHAN-ZHENG

    2015-01-01

    This study aimed to isolate rabbit adipose-derived stem cells (ADSCs) and explore the potential of platelet-rich plasma (PRP) in the chondrogenic differentiation of ADSCs, thereby potentially providing a new approach for the repair and regeneration of cartilage injury. Rabbit ADSCs were isolated and characterized by induction towards adipogenic, osteogenic and chondrogenic lineages in vitro. The isolated ADSCs were also cultured with or without 10% PRP. Immunofluorescence staining, toluidine blue staining and reverse transcription-quantitative polymerase chain reaction (RT-qPCR) were used to detect type II collagen (Col II) and aggrecan (AGC) expression. Col II immunofluorescence staining and toluidine blue staining indicated that following induction by autologous PRP, ADSCs manifested Col II and AGC expression. The expression of Col II and AGC mRNA was significantly upregulated in the PRP-treated cells when compared with that in control cells. Autologous PRP produced by laboratory centrifugation was able to promote the chondrogenic differentiation of rabbit ADSCs in vitro. PMID:26622340

  18. Planning and leading of the technological processes by mechanical working with microsoft project

    NASA Astrophysics Data System (ADS)

    Nae, I.; Grigore, N.

    2016-08-01

    Nowadays, fabrication systems and methods are being modified; new processing technologies come up, flow sheets develop a minimum number of phases, the flexibility of the technologies grows up, new methods and instruments of monitoring and leading the processing operations also come up. The technological course (route, entry, scheme, guiding) referring to the series of the operation, putting and execution phases of a mark in order to obtain the final product from the blank is represented by a sequence of activities realized by a logic manner, on a well determined schedule, with a determined budget and resources. Also, a project can be defined as a series of specific activities, methodical structured which they aim to finish a specific objective, within a fixed schedule and budget. Within the homogeneity between the project and the technological course, this research is presenting the defining of the technological course of mechanical chip removing process using Microsoft Project. Under these circumstances, this research highlights the advantages of this method: the celerity using of other technological alternatives in order to pick the optimal process, the job scheduling being constrained by any kinds, the standardization of some processing technological operations.

  19. Emerging Communication Technologies (ECT) Phase 4 Report

    NASA Technical Reports Server (NTRS)

    Bastin, Gary L.; Harris, William G.; Marin, Jose A.; Nelson, Richard A.

    2005-01-01

    The Emerging Communication Technology (ECT) project investigated three First Mile communication technologies in support of NASA s Crew Exploration Vehicle (CEV), Advanced Range Technology Working Group (ARTWG), and the Advanced Spaceport Technology Working Group (ASTWG). These First Mile technologies have the purpose of interconnecting mobile users with existing Range Communication infrastructures on a 24/7 basis. ECT is a continuation of the Range Information System Management (RISM) task started in 2002. This is the fourth year of the project.

  20. Ubiquitous Working: Do Work Versus Non-work Environments Affect Decision-Making and Concentration?

    PubMed

    Burmeister, Carolin P; Moskaliuk, Johannes; Cress, Ulrike

    2018-01-01

    New communication technologies and mobile devices have enabled knowledge workers to work independently of location and in more than one fixed environment (ubiquitous working). Previous research shows that physical environments can influence cognition and work performance. We manipulated environment (i.e., a virtual office as a typical work environment compared to a virtual garden as a non-work environment ) and time pressure (i.e., inducing time pressure vs. no time pressure ) in order to investigate whether the environment influences decision-making and concentration. N = 109 students participated in this laboratory experiment. We posited (a) that a work environment would activate a work-related schema which in turn would enhance concentration performance and make decisions more risky compared to non-work environments and (b) that the environmental effect is more pronounced if time pressure is present compared to conditions where no time pressure is present. We found modest hypothesis-confirming main effects of environment on decision-making and concentration but no interaction effect with time pressure. As we used an innovative methodology that entails several limitations, future research is needed to give insights into the process and to investigate whether results hold true for all types of work settings, work demands, or work activities.

  1. The Teacher's Role When Pupils Work on Task Using ICT in Project Work

    ERIC Educational Resources Information Center

    Postholm, May Britt

    2006-01-01

    Background: ICT (information and communication technology) and project work are challenging issues for many teachers to deal with in the classroom. For years there were predictions that teachers, textbooks and even schools would be replaced by new teaching and learning technology. This prediction does not appear to have come about. Cuban has…

  2. Technology in Education, 1988. Working Papers of Planning and Development Research. Working Paper 88-2.

    ERIC Educational Resources Information Center

    Sharon, Donna

    This report on technology in education has been prepared, primarily for TVOntario staff, to highlight new and growing educational applications and to summarize recent evaluations of earlier application efforts. The descriptions of trends and developments are classified by media format. Representative applications of the media include: (1)…

  3. [Characteristics of working conditions at metallurgy-related plants].

    PubMed

    Egorova, A M

    2008-01-01

    Working conditions at more versus less advanced technology steel plants of the Volgograd Region are analyzed. The working conditions at the less advanced technology plants are referred to as a very high occupational risk. It is necessary to work out measures to lower the poor impact of microclimate, dust, noise, to improve illumination, and to regulate labor at steel plants.

  4. Regulatory Technology Development Plan - Sodium Fast Reactor. Mechanistic Source Term - Trial Calculation. Work Plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Grabaskas, David; Bucknor, Matthew; Jerden, James

    2016-02-01

    The overall objective of the SFR Regulatory Technology Development Plan (RTDP) effort is to identify and address potential impediments to the SFR regulatory licensing process. In FY14, an analysis by Argonne identified the development of an SFR-specific MST methodology as an existing licensing gap with high regulatory importance and a potentially long lead-time to closure. This work was followed by an initial examination of the current state-of-knowledge regarding SFR source term development (ANLART-3), which reported several potential gaps. Among these were the potential inadequacies of current computational tools to properly model and assess the transport and retention of radionuclides duringmore » a metal fuel pool-type SFR core damage incident. The objective of the current work is to determine the adequacy of existing computational tools, and the associated knowledge database, for the calculation of an SFR MST. To accomplish this task, a trial MST calculation will be performed using available computational tools to establish their limitations with regard to relevant radionuclide release/retention/transport phenomena. The application of existing modeling tools will provide a definitive test to assess their suitability for an SFR MST calculation, while also identifying potential gaps in the current knowledge base and providing insight into open issues regarding regulatory criteria/requirements. The findings of this analysis will assist in determining future research and development needs.« less

  5. Technological Literacy for All: A Course Designed to Raise the Technological Literacy of College Students

    ERIC Educational Resources Information Center

    Baskette, Kimberly G.; Fantz, Todd D.

    2013-01-01

    Understanding what technology is, and is not, is the first step in becoming technologically literate. One should also understand how technology is created, how it works, how it shapes society, and how society shapes technology. This study was designed to gauge the ability of a single-semester course to raise students' technological literacy as…

  6. Explaining Work Exhaustion From a Coping Theory Perspective: Roles of Techno-Stressors and Technology-Specific Coping Strategies.

    PubMed

    Gaudioso, Fulvio; Turel, Ofir; Galimberti, Carlo

    2015-01-01

    The purpose of this study is to theoretically develop and empirically examine a general coping theory model which explicates the indirect effects of key job-related techno-stressors on job exhaustion. Through this study, we show that techno-stress creators are detrimental to employee well-being and should be treated accordingly. Specifically, we first argue that key techno-stress creators on the job, namely techno-invasion and techno-overload, drive unpleasant states such as work-family conflict and distress. Next, we rely on general coping theory and argue that people respond to these states differently, but with both adaptive and maladaptive technology-specific coping strategies. Adaptive coping behaviors are argued to ultimately reduce work exhaustion, and maladaptive coping strategies are argued to increase it. The proposed model was tested and validated with structural equation modeling techniques applied to self-reported data obtained from a sample of 242 employees of a large organization in the United States. Implications for theory and practice are discussed.

  7. Identification of underground mine workings with the use of global positioning system technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Canty, G.A.; Everett, J.W.; Sharp, M.

    1998-12-31

    Identification of underground mine workings for well drilling is a difficult task given the limited resources available and lack of reliable information. Relic mine maps of questionable accuracy and difficulty in correlating the subsurface to the surface, make the process of locating wells arduous. With the development of global positioning system (GPS), specific locations on the earth can be identified with the aid of satellites. This technology can be applied to mine workings identification given a few necessary, precursory details. For an abandoned mine treatment project conducted by the University of Oklahoma, in conjunction with the Oklahoma Conservation Commission, amore » Trimble ProXL 8 channel GPS receiver was employed to locate specific points on the surface with respect to a mine map. A 1925 mine map was digitized into AutoCAD version 13 software. Surface features identified on the map, such as mine adits, were located and marked in the field using the GPS receiver. These features were than imported into AutoCAD and referenced with the same points drawn on the map. A rubber sheeting program, Multric, was used to tweak the points so the map features correlated with the surface points. The correlation of these features allowed the map to be geo-referenced with the surface. Specific drilling points were located on the digitized map and assigned a latitude and longitude. The GPS receiver, using real time differential correction, was used to locate these points in the field. This method was assumed to be relatively accurate, to within 5 to 15 feet.« less

  8. Hyaluronan-Based Therapy for Metastatic Prostate Cancer

    DTIC Science & Technology

    2016-09-01

    forward 5′-TGT GAC TTT GGT TGT TCC GTT GC-3′ and reverse 5′-ACC TGA GCC GAT GCA ACA ACA G-3′; DR5, forward 5′- AAG ACC CTT GTG CTC GTT GT-3′ and...reverse 5′-AGG TGG ACA CAA TCC CTC TG-3′; actin, forward 5′- TCC CTG GAG AAG AGC TAC GA-3′ and reverse 5′-AGC ACT GTG TTG GCG TAC AG-3′. 2.2.5. Death

  9. Innovation leadership: new perspectives for new work.

    PubMed

    Malloch, Kathy

    2010-03-01

    The industrial age command and control leadership style and supporting infrastructure are ineffective in meeting the challenges of the increased availability and sharing of information, the media used for knowledge transfer, the changing range and types of relationships between individuals, and the time required to transfer and share information. What has not changed is the need for effective personal relationships in the evaluation and selection of new technologies; human to human sensitivity, acknowledgment, and respect for the patient care experience. As individuals embrace these new technologies, the essence of the innovation leader emerges to purposefully guide, assess, integrate, and synthesize technology into the human work of patient care. Building organizational infrastructures with openness for technology and innovations to enhance effective patient care relationships now requires an innovation skill set that understands and integrates human needs with the best of technology. In this article a brief description of innovation leadership is presented as the backdrop for change along with 4 significant changes in work processes that have irreversibly altered health care work, the trimodal organizational structure to accommodate operations, innovation, and transition between the 2, and finally, individual and team behaviors that emphasize the work of innovation. Copyright 2010 Elsevier Inc. All rights reserved.

  10. Australian University Technology Transfer Managers: Backgrounds, Work Roles, Specialist Skills and Perceptions

    ERIC Educational Resources Information Center

    Harman, Grant; Stone, Christopher

    2006-01-01

    Technology transfer managers are a new group of specialist professionals engaged in facilitating transfer of university research discoveries and inventions to business firms and other research users. With relatively high academic qualifications and enjoying higher salaries than many other comparable university staff, technology transfer managers…

  11. Technologies in older people's care.

    PubMed

    Andersson Marchesoni, Maria; Axelsson, Karin; Fältholm, Ylva; Lindberg, Inger

    2017-03-01

    The tension between care-based and technology-based rationalities motivates studies concerning how technology can be used in the care sector to support the relational foundation of care. This study interprets values related to care and technologies connected to the practice of good care. This research study was part of a development project aimed at developing innovative work practices through information and communication technology. Participants and research context: All staff (n = 18) working at two wards in a care facility for older people were asked to participate in interviews, and 12 accepted. We analysed the data using latent content analysis in combination with normative analysis. Ethical considerations: The caregivers were informed that participation was voluntary and that they could drop out at any time without providing any explanation. Four values were identified: 'presence', 'appreciation', 'competence' and 'trust'. Caregivers wanted to focus on care receivers as unique persons, a view that they thought was compromised by time-consuming and beeping electronic devices. Appraising from next-of-kin and been seen as someone who can contribute together with knowledge to handle different situations were other desires. The caregivers also desired positive feedback from next-of-kin, as they wanted to be seen as professionals who have the knowledge and skills to handle difficult situations. In addition, the caregivers wanted their employer to trust them, and they wanted to work in a calm environment. Caregivers' desire for disturbance-free interactions, being valued for their skills and working in a trustful working environment were interpreted as their base for providing good care. The caregivers' arguments are based on caring rationality, and sometimes they felt the technological rationality interfered with their main mission, providing quality care. Introducing new technology in caring should support the caring relationship. Although society's overall

  12. Research and Technology

    NASA Technical Reports Server (NTRS)

    1997-01-01

    As the NASA Center responsible for preparing and launching space missions, the John F. Kennedy Space Center (KSC) is placing increasing emphasis on its advanced technology development program. This program encompasses the efforts of the entire KSC team, consisting of Government and contractor personnel, working in partnership with academic institutions and commercial industry. This edition of the KSC Research and Technology 1997 Annual Report covers the efforts of these contributors to the KSC advanced technology development program, as well as our technology transfer activities.

  13. Patent Information Use in Engineering Technology Design: An Analysis of Student Work

    ERIC Educational Resources Information Center

    Phillips, Margaret; Zwicky, Dave

    2017-01-01

    How might engineering technology students make use of patent information in the engineering design process? Librarians analyzed team project reports and personal reflections created by students in an undergraduate mechanical engineering technology design course, revealing that the students used patents to consider the patentability of their ideas,…

  14. Understanding Unintended Consequences and Health Information Technology:. Contribution from the IMIA Organizational and Social Issues Working Group.

    PubMed

    Kuziemsky, C E; Randell, R; Borycki, E M

    2016-11-10

    No framework exists to identify and study unintended consequences (UICs) with a focus on organizational and social issues (OSIs). To address this shortcoming, we conducted a literature review to develop a framework for considering UICs and health information technology (HIT) from the perspective of OSIs. A literature review was conducted for the period 2000- 2015 using the search terms "unintended consequences" and "health information technology". 67 papers were screened, of which 18 met inclusion criteria. Data extraction was focused on the types of technologies studied, types of UICs identified, and methods of data collection and analysis used. A thematic analysis was used to identify themes related to UICs. We identified two overarching themes. One was the definition and terminology of how people classify and discuss UICs. Second was OSIs and UICs. For the OSI theme, we also identified four sub-themes: process change and evolution, individual-collaborative interchange, context of use, and approaches to model, study, and understand UICs. While there is a wide body of research on UICs, there is a lack of overall consensus on how they should be classified and reported, limiting our ability to understand the implications of UICs and how to manage them. More mixed-methods research and better proactive identification of UICs remain priorities. Our findings and framework of OSI considerations for studying UICs and HIT extend existing work on HIT and UICs by focusing on organizational and social issues.

  15. Desflurane usage during anesthesia with and without N2O using FLOW-i Automatic Gas Control with three different wash-in speeds.

    PubMed

    De Medts, Robrecht; Carette, Rik; De Wolf, Andre M; Hendrickx, Jan F A

    2017-06-09

    AGC ® (Automatic Gas Control) is the FLOW-i's automated low flow tool (Maquet, Solna, Sweden) that target controls the inspired O 2 (F I O 2 ) and end-expired desflurane concentration (F A des) while (by design) exponentially decreasing fresh gas flow (FGF) during wash-in to a maintenance default FGF of 300 mL min -1 . It also offers a choice of wash-in speeds for the inhaled agents. We examined AGC performance and hypothesized that the use of lower wash-in speeds and N 2 O both reduce desflurane usage (Vdes). After obtaining IRB approval and patient consent, 78 ASA I-II patients undergoing abdominal surgery were randomly assigned to 1 of 6 groups (n = 13 each), depending on carrier gas (O 2 /air or O 2 /N 2 O) and wash-in speed (AGC speed 2, 4, or 6) of desflurane, resulting in groups air/2, air/4, air/6, N 2 O/2, N 2 O/4, and N 2 O/6. The target for F I O 2 was set at 35%, while the F A des target was selected so that the AGC displayed 1.3 MAC (corrected for the additive affect of N 2 O if used). AGC was activated upon starting mechanical ventilation. Varvel's criteria were used to describe performance of achieving the targets. Patient demographics, end-expired N 2 O concentration, MAC, FGF, and Vdes were compared using ANOVA. Data are presented as mean ± standard deviation, except for Varvel's criteria (median ± quartiles). Patient demographics did not differ among the groups. Median performance error was -2-0% for F I O 2 and -3-1% for F A des; median absolute performance error was 1-2% for F I O 2 and 0-3% for F A des. MAC increased faster in N 2 O groups, but total MAC decreased 0.1-0.25 MAC below that in the O 2 /air groups after 60 min. The effect of wash-in speed on Vdes faded over time. N 2 O decreased Vdes by 62%. AGC performance for O 2 and desflurane targeting is excellent. After 1 h, the wash-in speeds tested are unlikely to affect desflurane usage. N 2 O usage decreases Vdes proportionally with its reduction in F A tdes.

  16. Topographic Control of Aboveground Carbon Pools Across an Environmental Gradient, Eastern Slope of the Rocky Mountains, Colorado.

    NASA Astrophysics Data System (ADS)

    Swetnam, T. L.; Brooks, P. D.; Gallo, E. L.; Barnard, H. R.; Harpold, A. A.

    2015-12-01

    Evaluating at high spatial-resolution the topographical and ecological structures of the critical zone (CZ) are now routine with aerial LiDAR. Here we evaluated the eco-hydrological differences of topographic metrics (the independent variables) versus individual tree and gridded aboveground carbon (AGC) pools (as dependent variables) at multiple length-scales across an elevation modified gradient of precipitation and temperature in the Boulder Creek CZ Observatory Watershed, Colorado USA. We describe the responses in AGC within the context of a three-zone eco-hydrological model, e.g. toe slope and valley bottoms (Zone 1), transitional hillslopes (Zone 2), and upper slopes to ridges (Zone 3). In a GIS we compared three separate zero-order basins: (1) the Betasso Preserve: 1,810-2,024 meters above mean sea level (m aμsl), area = 0.45 km2, n = 17,286 trees; (2) Upper and Lower Gordon Gulch: 2,446-2,737 m aμsl, area = 3.57 km2, n = 178,469 trees; and (3) Como Creek: 2,900m-3,560 m aμsl, area = 6.64 km2, n = 317,274 trees. In each of the three catchments Zone 1 held the greatest mean AGC (μ = 52.88-60.97 Mg C ha-1) and maximum AGC (99% confidence interval (CI, p = 0.01) = 152.95-184.95 Mg C ha-1) relative to Zone 2 (μ = 27.84-44.52 Mg C ha-1, 99% CI = 99.67-122.4 Mg C ha-1) and Zone 3 (μ = 12.63-30.33 Mg C ha-1, 99% CI = 62.16-92.65 Mg C ha-1). Topography with negative general curvatures (i.e. convergent shapes) had greater AGC (μ = 73.7-96.3 Mg C ha-1, 99% CI = 189.0-355.8 Mg C ha-1) than positive general curvatures (i.e. divergent shapes) (μ = 17.4-30.8 Mg C ha-1, 99% CI = 88.2-120.4 Mg C ha-1), but only when evaluated at longer length scales (<10 m). Larger AGC pools are postulated to be related to (1) increased soil depth which provides larger rooting zones and (2) access to groundwater along Zone 1, vs Zones 2 and 3 which have (a) shallower soils and (b) less or zero accessibility to groundwater.

  17. Demonstration of Essential Reliability Services by a 300-MW Solar Photovoltaic Power Plant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Loutan, Clyde; Klauer, Peter; Chowdhury, Sirajul

    to contribute to system-wide reliability. It was shown that the First Solar plant can provide essential reliability services related to different forms of active and reactive power controls, including plant participation in AGC, primary frequency control, ramp rate control, and voltage regulation. For AGC participation in particular, by comparing the PV plant testing results to the typical performance of individual conventional technologies, we showed that regulation accuracy by the PV plant is 24-30 points better than fast gas turbine technologies. The plant's ability to provide volt-ampere reactive control during periods of extremely low power generation was demonstrated as well. The project team developed a pioneering demonstration concept and test plan to show how various types of active and reactive power controls can leverage PV generation's value from being a simple variable energy resource to a resource that provides a wide range of ancillary services. With this project's approach to a holistic demonstration on an actual, large, utility-scale, operational PV power plant and dissemination of the obtained results, the team sought to close some gaps in perspectives that exist among various stakeholders in California and nationwide by providing real test data.« less

  18. The use of information and communication technologies to support working carers of older people - a qualitative secondary analysis.

    PubMed

    Andersson, Stefan; Magnusson, Lennart; Hanson, Elizabeth

    2016-03-01

    Family care support services have mainly focused on older spousal carers of older people and have largely overlooked working carers, whom combine paid work with informal/family care responsibilities. Recently, however, information and communication technology (ICT) systems have been identified as a potentially flexible way of supporting working carers. The aim of this study was to describe nursing and support staff's experiences of using ICT for information, e-learning and support of working carers of older people. The study employed a descriptive, qualitative approach conducting a qualitative secondary analysis of two original data sets. In total, seventeen professional staff members from two municipal family carer support units in Sweden that had implemented ICTs were interviewed using a semi-structured interview guide consisting of open-ended questions. Two data sets were merged using latent qualitative content analysis. Secondary analysis produced three subthemes and an overall theme, a virtual road as a carriageway for the support of working carers, consisting of both enabling and hindering aspects in family support. This theme provides access points in both directions and is based on caring instruments that enable nursing staff's support role. The staff's sustainability and ability to support is influenced by caring opportunities and barriers. The findings suggest the ICTs to be flexible structures that provided nursing staff with a means and method to support working carers of older people. To overcome barriers to its use, measures to optimise support for working carers and the older person are needed. The use of ICTs provides nurses with a means to offer support to working carers of older people and enables carers to be informed, to learn and to share their burdens with others when caring for an older family member. © 2015 John Wiley & Sons Ltd.

  19. Technology to Support Teachers Using Evidence from Student Work to Customize Technology-Enhanced Inquiry Units

    ERIC Educational Resources Information Center

    Matuk, Camillia F.; Linn, Marcia C.; Eylon, Bat-Sheva

    2015-01-01

    Teachers' involvement in curriculum design is essential for sustaining the relevance of technology-enhanced learning materials. Customizing--making small adjustments to tailor given materials to particular situations and settings--is one design activity in which busy teachers can feasibly engage. Research indicates that customizations based…

  20. Changing Work and Work-Family Conflict: Evidence from the Work, Family, and Health Network*

    PubMed Central

    Kelly, Erin L.; Moen, Phyllis; Oakes, J. Michael; Fan, Wen; Okechukwu, Cassandra; Davis, Kelly D.; Hammer, Leslie; Kossek, Ellen; King, Rosalind Berkowitz; Hanson, Ginger; Mierzwa, Frank; Casper, Lynne

    2013-01-01

    Schedule control and supervisor support for family and personal life are work resources that may help employees manage the work-family interface. However, existing data and designs have made it difficult to conclusively identify the effects of these work resources. This analysis utilizes a group-randomized trial in which some units in an information technology workplace were randomly assigned to participate in an initiative, called STAR, that targeted work practices, interactions, and expectations by (a) training supervisors on the value of demonstrating support for employees’ personal lives and (b) prompting employees to reconsider when and where they work. We find statistically significant, though modest, improvements in employees’ work-family conflict and family time adequacy and larger changes in schedule control and supervisor support for family and personal life. We find no evidence that this intervention increased work hours or perceived job demands, as might have happened with increased permeability of work across time and space. Subgroup analyses suggest the intervention brings greater benefits to employees more vulnerable to work-family conflict. This study advances our understanding of the impact of social structures on individual lives by investigating deliberate organizational changes and their effects on work resources and the work-family interface with a rigorous design. PMID:25349460

  1. Changing Work and Work-Family Conflict: Evidence from the Work, Family, and Health Network*

    PubMed

    Kelly, Erin L; Moen, Phyllis; Oakes, J Michael; Fan, Wen; Okechukwu, Cassandra; Davis, Kelly D; Hammer, Leslie; Kossek, Ellen; King, Rosalind Berkowitz; Hanson, Ginger; Mierzwa, Frank; Casper, Lynne

    2014-06-01

    Schedule control and supervisor support for family and personal life are work resources that may help employees manage the work-family interface. However, existing data and designs have made it difficult to conclusively identify the effects of these work resources. This analysis utilizes a group-randomized trial in which some units in an information technology workplace were randomly assigned to participate in an initiative, called STAR, that targeted work practices, interactions, and expectations by (a) training supervisors on the value of demonstrating support for employees' personal lives and (b) prompting employees to reconsider when and where they work. We find statistically significant, though modest, improvements in employees' work-family conflict and family time adequacy and larger changes in schedule control and supervisor support for family and personal life. We find no evidence that this intervention increased work hours or perceived job demands, as might have happened with increased permeability of work across time and space. Subgroup analyses suggest the intervention brings greater benefits to employees more vulnerable to work-family conflict. This study advances our understanding of the impact of social structures on individual lives by investigating deliberate organizational changes and their effects on work resources and the work-family interface with a rigorous design.

  2. Synthesis and characterization of Ag+ ion conducting glassy electrolytes

    NASA Astrophysics Data System (ADS)

    Chandra, Angesh; Bhatt, Alok; Chandra, Archana

    2013-07-01

    Synthesis and characterization of new Ag+ ion conducting glassy systems: x[0.75AgI:0.25AgC1]: (1 - x)[Ag2O:P2O5], where 0.1 < x < 1 in molar weight fraction, are reported. The present glassy electrolytes have been synthesized by melt-quench technique using a high-speed twin roller-quencher. An alternate host salt: "quenched [0.75AgI:0.25AgC1] mixed system/solid solution", has been used in place of the traditional host AgI. The compositional dependence conductivity studies on the glassy systems: x[0.75AgI:0.25AgC1]:(1 - x)[Ag2O:P2O5] as well as xAgI:(1 - x)[Ag2O:P2O5] prepared identically, indicated that the composition at x = 0.75 exhibited the highest room temperature conductivity (σ ~ 5.5 x 10-3 S cm-1). The composition: 0.75[0.75AgI:0.25AgC1]:0.25[Ag2O:P2O5] has been referred to as optimum conducting composition (OCC). The some basic ion transport parameters viz. ionic conductivity (σ), ionic mobility (μ), mobile ion concentration (n), ionic drift velocity (vd), ion transference number (tion) and activation energy (Ea) values have been characterized with the help of various experimental techniques. A solid state battery was fabricated and its basic cell parameters calculated.

  3. Cost-effectiveness analysis of apatinib treatment for chemotherapy-refractory advanced gastric cancer.

    PubMed

    Chen, Hong-Dou; Zhou, Jing; Wen, Feng; Zhang, Peng-Fei; Zhou, Ke-Xun; Zheng, Han-Rui; Yang, Yu; Li, Qiu

    2017-02-01

    Apatinib, a third-line or later treatment for advanced gastric cancer (aGC), was shown to improve overall survival and progression-free survival (PFS) compared with placebo in the phase III trial. Given the modest benefit with high costs, we further evaluated the cost-effectiveness of apatinib for patients with chemotherapy-refractory aGC. A Markov model was developed to simulate the disease process of aGC (PFS, progressive disease, and death) and estimate the incremental cost-effectiveness ratio (ICER) of apatinib to placebo. The health outcomes and utility scores were derived from the phase III trial and previously published sources, respectively. Total costs were calculated from the perspective of the Chinese health-care payer. Sensitivity analysis was used to explore model uncertainties. Treatment with apatinib was estimated to provide an incremental 0.09 quality-adjusted life years (QALYs) at an incremental cost of $8113.86 compared with placebo, which resulted in an ICER of $90,154.00 per QALY. Sensitivity analysis showed that across the wide variation of parameters, the ICER exceeded the willingness-to-pay threshold of $23,700.00 per QALY which was three times the Gross Domestic Product per Capita in China. Apatinib is not a cost-effective option for patients with aGC who experienced failure of at least two lines chemotherapy in China. However, for its positive clinical value and subliminal demand, apatinib can provide a new therapeutic option.

  4. ENVIRONMENTAL TECHNOLOGY VERIFICATION REPORT - PORTABLE GAS CHROMATOGRAPH ELECTRONIC SENSOR TECHNOLOGY MODEL 4100

    EPA Science Inventory

    The U.S. Environmental Protection Agency, through the Environmental Technology Verification Program, is working to accelerate the acceptance and use of innovative technologies that improve the way the United States manages its environmental problems. As part of this program, the...

  5. Sandia National Laboratories: Working with Sandia: Prospective Suppliers

    Science.gov Websites

    Audit Sandia's Economic Impact Licensing & Technology Transfer Browse Technology Portfolios Report Economic Impact Environmental Reports Fact Sheets Search Sandia Publications Labs Accomplishments /Technology Transfer Technology Partnerships Economic Impact Facebook Twitter YouTube Flickr RSS Working with

  6. Orienting the Work-Based Curriculum Towards Work Process Knowledge: A Rationale and a German Case Study

    ERIC Educational Resources Information Center

    Boreham, Nick

    2004-01-01

    The term 'work process knowledge' refers to the knowledge needed for working in flexible and innovative business environments, including those in which information and communication technologies have been introduced to integrate previously separated production functions. It involves a systems-level understanding of the work process in the…

  7. New technology and its impact on well being.

    PubMed

    Rafnsdottir, Gudbjorg Linda; Gudmundsdottir, Margret Lilja

    2004-01-01

    Great changes have come about in the last decade regarding the organization of work. High technology and the steadily increasing ideology of technocracy has produced a profound effect on the organization of work in some workplaces. This effect has made the psychosocial and physical working environment tougher, especially for women. The results we are presenting here show that when dividing fishing factories into three technological stages; low technology, middle technology and high technology, the job strain was highest and the decision authority by the employee was lowest in the high technological factories. This even had an impact on health and on the atmosphere at the workplace, where the employees in the high technological factories were more likely to complain about several health problems as well as about low degrees of cheerfulness at the workplace and tiresome jobs. However, these same people were the most positive towards the implementation of the high technology and the new way of organizing their job that the technology introduced.

  8. Engaging Education: Integrating Work, Technology and Learning for Adults.

    ERIC Educational Resources Information Center

    Department of Housing and Urban Development, Washington, DC.

    This guide is for Neighborhood Networks center staff and volunteers who want to learn how centers across the country are helping adults meet work force demands. It provides resources to work force development programs so examples can be tailored to meet the needs of other communities. It focuses on challenges that integrating academics and job…

  9. Working Out Works for Shawn Kelly | Poster

    Cancer.gov

    By Nancy Parrish, Staff Writer When Shawn Kelly found out last year that he had high blood pressure, he was determined to do something about it. Luckily for Kelly, an instrumentation technician III, Facilities Maintenance and Engineering, he works at the Advanced Technology Research Facility (ATRF), where he can take advantage of the gym there, known as the Wellness Center.

  10. Telehealth: Implications for Social Work.

    ERIC Educational Resources Information Center

    McCarty, Dawn; Clancy, Catherine

    2002-01-01

    The use of modern information technology to deliver health services to remote locations presents both opportunities and problems for social workers. This article examines how communication technology such as e-mail and video conferencing affect social work practice. Issues are raised about the ethical, legal, and client relationship…

  11. Bridging the Professional Digital Divide: Comparative Analysis of Technology Usage Behaviors across the Working Lifespan of Professional Social Workers: A Quantitative Study

    ERIC Educational Resources Information Center

    Bonner, Aisha Ain

    2012-01-01

    The focus of this research is the mandatory use of Computer Based Technology (CBT) with social work professionals. Such a study is important in order to investigate which determinants are essential for social workers 45 and older to achieve adoption of CBT. The membership list of the National Association of Social Workers provided access to…

  12. Intentional Teaching with Technology

    ERIC Educational Resources Information Center

    Mooney, Eileen B.

    2018-01-01

    Top-down implementation of technology is one of the most pervasive phenomena of the last couple of decades in educational history. It is the subject of many books, articles, and blog posts on how to fix schools or why educational technology is not working in the classroom. The idea of providing teachers with technology so they can make students…

  13. RHC Technologies and Applications

    EPA Pesticide Factsheets

    This page provides a portal to learning about several of the most common types of renewable heating and cooling technologies and end use applications. A clickable diagram compares technologies and applications with respect to their working temperatures.

  14. QuEST: Qualifying Environmentally Sustainable Technologies. Volume 2

    NASA Technical Reports Server (NTRS)

    Brown, Christina (Editor)

    2007-01-01

    TEERM focuses its validation efforts on technologies that have shown promise in laboratory testing, but lack testing under realistic or field environment. Mature technologies have advantages over those that are still in the developmental stage such as being more likely to be transitioned into a working environment. One way TEERM begins to evaluate the suitability of technologies is through Technology Readiness Levels (TRLs). TRLs are a systematic metric/measurement system that supports assessments of the maturity of a particular technology and the consistent comparison of maturity between different types of technology. TEERM generally works on demonstrating/validating alternatives that fall within TRLs 5-9. In instances where a mature technology does not exist for a particular Agency application, TEERM works with technology development groups and programs such as NASA's Innovative Partnerships Program (IPP). The IPP's purpose is to identify and document available technologies in light of NASA's needs, evaluate and prioritize those technologies, and reach out to find new partners. All TEERM projects involve multiple partners. Partnering reduces duplication of effort that otherwise might occur if individuals worked their problems alone. Partnering also helps reduce individual contributors' shares of the total cost of technology validation. Through collaboration and financial commitment from project stakeholders and third-party sources, it is possible to fully fund expensive demonstration/validation efforts.

  15. Gender, "Discourse," and Technology. Center for Equity and Diversity Working Paper 5.

    ERIC Educational Resources Information Center

    Hanson, Katherine

    This paper identifies and discusses the connections between the way individuals frame their world based on the language they use and the impact of language and stereotyping on the perception that computer technology is primarily for certain individuals. The study explores how some of the dimensions of the language of computers and technology,…

  16. AGARD Flight Test Instrumentation Series. Volume 13. Practical Aspects of Instrumentation System Installation

    DTIC Science & Technology

    1981-09-01

    III I’ CANOWN" AA HNE Figure 3.3-4 Rzxsqle. Block Diagrami 24 PI LOT AIRBORNE IGROUND AGC AMPLIFIER AGC AMPLIFIER BASE • FM BASEBAND LINKE SQUARE I OO...in that T 0- •,~ ao •, _4 U- - & - @ Figure 3.3-6 Point to Point Inter- Connect Diagram. 25 the wires are merged, or joined, into no @ Lot ".U~ AFT...result in a " bottoning -out" of the isolators during high amplitude vibration. For a properly selected rubber mount, the wearing should be conservative

  17. In-flight wobble identification for Galileo

    NASA Technical Reports Server (NTRS)

    Lai, J. Y.; Wong, E. C.

    1984-01-01

    To achieve in-flight wobble compensation for Galileo, wobble identification is implemented using star scanner data or automatic gain control (AGC) signal as measurement in all-spin mode. The star scanner provides spacecraft attitude in inertial space while the AGC signal provides the spacecraft pointing relative to earth. A linear observation model is defined for each sensor which is being applied to a Kalman Estimator. It can be shown from simulation that better result can be achieved using a combined set of data than any one sensor alone due to correlation reduction among error sources.

  18. Negotiating technology-mediated interaction in health care

    PubMed Central

    Håland, Erna; Melby, Line

    2015-01-01

    The health-care sector is increasingly faced with different forms of technology that are introduced to mediate interaction, thus fully or partially replacing face-to-face meetings. In this article we address health personnel's experiences with three such technologies, namely: electronic messages, video conferences and net-based discussion forums. Drawing on Goffman's perspectives on interaction and frame, we argue that when technologies are introduced to mediate interaction, new frames for understanding and making sense of situations are created. These new frames imply new ways of organising and making sense of experience, and require work by the participants in the interaction. In this article, based on interviews from two Norwegian research projects, we investigate health personnel's work to make sense of technology-mediated interaction in health care. We discuss this work represented in four categories: how to perform in a competent manner, how to negotiate immediacy, how to enable social cues and how to establish and maintain commitment. Concluding, we argue that the introduction of mediating technologies redefines what is considered up-to-date, ‘good' health-care work and challenges health personnel to change (some of) their work practices and moves, as a result, far beyond simple interventions aimed at making work more efficient. PMID:25685073

  19. Lewis Incubator for Technology (LIFT)

    NASA Technical Reports Server (NTRS)

    Zeman, Wayne P.; King, Joseph B.; Jankura, Richard E., Jr.

    2004-01-01

    This report summarizes the work done to operate the Lewis Incubator for Technology for the period October 2000 through September 2004. The Lewis Incubator helped the startup and growth of technology based businesses with the potential to incorporate technology from the NASA Glenn Research Center.

  20. Crosscutting Technology Development at the Center for Advanced Separation Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Christopher E. Hull

    2006-09-30

    This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  1. CROSSCUTTING TECHNOLOGY DEVELOPMENT AT THE CENTER FOR ADVANCED SEPARATION TECHNOLOGIES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Christopher E. Hull

    2006-05-15

    This Technical Progress Report describes progress made on the twenty nine subprojects awarded in the second year of Cooperative Agreement DE-FC26-02NT41607: Crosscutting Technology Development at the Center for Advanced Separation Technologies. This work is summarized in the body of the main report: the individual sub-project Technical Progress Reports are attached as Appendices.

  2. National Commission on New Technological Uses of Copyrighted Works, Meeting Number Three (White Plains and New York, N.Y., December 18-19, 1975).

    ERIC Educational Resources Information Center

    Library of Congress, Washington, DC. Copyright Office.

    The first day of the National Commission on New Technological Uses of Copyrighted Works' (CONTU) third meeting was spent at IBM processing headquarters, where commissioners learned about the history and terminology of computers, information storage methods, computer capabilities, computers and copyrights, future trends, and costs. On the second…

  3. Technology in action

    NASA Technical Reports Server (NTRS)

    1992-01-01

    In keeping with the NASA Administrator's announcement that technology transfer will become a fundamental mission of NASA, the Marshall Space Flight Center (MSFC) has initiated new programs to reach the heartland of U.S. industry. The Center has continued to expand its already well-established outreach program aimed at helping American business, industry, and academia at the grassroots level. The goal is to ensure that America regains and maintains its proper place of leadership among the world's technologically developed nations. MSFC's national goal is to enhance America's competitiveness in the world marketplace, fortify the value of the dollar, and ensure technological breakthroughs by American laboratories benefit taxpayers and industries. The Technology Utilization (TU) Office at MSFC believes a number of measures are possible to slow, then halt, and ultimately reverse the erosion of American technological leadership. MSFC's TU Office is reaching out to American industry on an increasingly broadening scope, facilitating the transfer of NASA derived technologies to American businesses, industries, educational institutions, and individuals. There are many valid approaches to achieving this goal. Some, such as the National Technology Initiative, begin at the top and work down through America's top corporate structure. Others, such as the technology transfer program that MSFC has implemented, begin at the one-on-one, grassroots level -- working with small and medium-sized firms that form the bulk of American industry. What can be done by one NASA center is, admittedly, limited. But by extrapolating this one-on-one approach to the more than 700 Federal laboratories, a great deal can be accomplished. This report contains an examination of outreach and in reach programs, problem statements programs, applications projects, new technology reporting, new technology administration, and the need for increased resources to further facilitate technology transfer.

  4. The geochemical nature of the Archean Ancient Gneiss Complex and Granodiorite Suite, Swaziland: a preliminary study

    USGS Publications Warehouse

    Hunter, D.R.; Barker, F.; Millard, H.T.

    1978-01-01

    The Ancient Gneiss Complex (AGC) of Swaziland, an Archean gray gneiss complex, lies southeast and south of the Barberton greenstone belt and includes the most structurally complex and highly metamorphosed portions of the eastern Kaapvaal craton. The AGC is not precisely dated but apparently is older than 3.4 Ga. The AGC consists of three major units: (a) a bimodal suite of closely interlayered siliceous, low-K gneisses and metabasalt; (b) homogeneous tonalite gneiss; and (c) interlayered siliceous microcline gneiss, metabasalt, and minor metasedimentary rocks - termed the metamorphite suite. A geologically younger gabbro-diorite-tonalite-trondhjemite suite, the Granodiorite Suite, is spatially associated with the AGC and intrusive into it. The bimodal suite consists largely of two types of low-K siliceous gneiss: one has SiO2 14%, low Rb/Sr ratios, and depleted heavy rare earth elements (REE's); the other has SiO2 > 75%, Al2O3 < 13%, high Rb/Sr ratios, and relatively abundant REE's except for negative Eu anomalies. The interlayered metabasalt ranges from komatiitic to tholeiitic compositions. Lenses of quartz monzonitic gneiss of K2O/Na2O close to 1 form a minor part of the bimodal suite. Tonalitic to trondhjemitic migmatite locally is abundant and has major-element abundances similar to those of non-migmatitic varieties. The siliceous gneisses of the metamorphic suite show low Al2O, K2O/Na2O ratios of about 1, high Rb/Sr ratios, moderate REE abundances and negative Eu anomalies. K/Rb ratios of siliceous gneisses of the bimodal suite are very low (???130); of the tonalitic gneiss, low (???225); of the siliceous gneiss of the metamorphite suite, moderate (???300); and of the Granodiorite Suite, high (???400). Rocks of the AGC differ geochemically in several ways from the siliceous volcanic and hypabyssal rocks of the Upper Onverwacht Group and from the diapirs of tonalite and trondhjemite that intrude the Swaziland Group. ?? 1978.

  5. Situated, strategic, and AI-Enhanced technology introduction to healthcare.

    PubMed

    Bushko, Renata G

    2005-01-01

    We work hard on creating AI-wings for physicians to let them fly higher and faster in diagnosing patients--a task that physicians do not want to automate. What we do not work hard on is determining the ENVIRONMENT in which physicians' AI wings are supposed to function. It seems to be a job for social/business analysts that have their own separate kingdom. For the sake of all of us (potential patients!) social/business consultants and their methodologies should not be treated as a separate kingdom. The most urgent task is to achieve synergy between (1) AI/Fuzzy/Neural research, (2) Applied medical AI, (3) Social/Business research on medical institutions. We need this synergy in order to assure humanistic medical technology; technology flexible and sensitive enough to facilitate healthcare work while leaving space for human pride and creativity. In order to achieve humanistic technology, designers should consider the impact of technological breakthroughs on the organizations in which this technology will function and the nature of work of humans destined to use this technology. Situated (different for each organization), Strategic (based on an in-depth knowledge of Healthcare business), and AI-Enhanced (ended with a dynamic model) method for introducing technology to Healthcare allows identifying areas where technology can make medical work easier. Using this method before automating human work will get us closer to the ideal where there is no discontinuity between design and use of programs; where the technology matches users' needs perfectly--the world with humanistic technology and healthcare workers with AI-wings.

  6. IVS Technology Coordinator Report

    NASA Technical Reports Server (NTRS)

    Whitney, Alan

    2013-01-01

    This report of the Technology Coordinator includes the following: 1) continued work to implement the new VLBI2010 system, 2) the 1st International VLBI Technology Workshop, 3) a VLBI Digital- Backend Intercomparison Workshop, 4) DiFX software correlator development for geodetic VLBI, 5) a review of progress towards global VLBI standards, and 6) a welcome to new IVS Technology Coordinator Bill Petrachenko.

  7. Sex Differences in Japanese Work Ethics.

    ERIC Educational Resources Information Center

    Engel, John W.

    Work values influence economic productivity of individuals and families worldwide. Since Japan's recent technological and economic productivity and growth have been phenomenal, a study was conducted to compare contemporary Japanese men's and women's work related values and beliefs. Work values questionnaires were distributed to over 900 Japanese…

  8. Design of an anti-Rician-fading modem for mobile satellite communication systems

    NASA Technical Reports Server (NTRS)

    Kojima, Toshiharu; Ishizu, Fumio; Miyake, Makoto; Murakami, Keishi; Fujino, Tadashi

    1995-01-01

    To design a demodulator applicable to mobile satellite communication systems using differential phase shift keying modulation, we have developed key technologies including an anti-Rician-fading demodulation scheme, an initial acquisition scheme, automatic gain control (AGC), automatic frequency control (AFC), and bit timing recovery (BTR). Using these technologies, we have developed one-chip digital signal processor (DSP) modem for mobile terminal, which is compact, of light weight, and of low power consumption. Results of performance test show that the developed DSP modem achieves good performance in terms of bit error ratio in mobile satellite communication environment, i.e., Rician fading channel. It is also shown that the initial acquisition scheme acquires received signal rapidly even if the carrier-to-noise power ratio (CNR) of the received signal is considerably low.

  9. Underpinning the STEM Agenda through Technological Textiles? An Exploration of Design Technology Teachers' Attitudes

    ERIC Educational Resources Information Center

    Hughes, Chris; Bell, Dawne

    2011-01-01

    This paper discusses ongoing research into the role of design and technology education in emerging post industrial economies. Previous work (Hughes et al., 2010) focused on the changing characteristics of textiles technology in modern times and discussed how this could inform a design and technology curriculum related to the needs of a modern…

  10. Technology Transfer Network and Affiliations

    NASA Technical Reports Server (NTRS)

    2003-01-01

    The NASA Technology Transfer Partnership program sponsors a number of organizations around the country that are designed to assist U.S. businesses in accessing, utilizing, and commercializing NASA-funded research and technology. These organizations work closely with the Technology Transfer Offices, located at each of the 10 NASA field centers, providing a full range of technology transfer and commercialization services and assistance.

  11. Gender, technology and jobs.

    PubMed

    Brynin, Malcolm

    2006-09-01

    Men have traditionally gained more than women from access to technologies at work which bring prestige, job security, more satisfying work and higher pay. Typically female jobs have centred on technologies, if they have at all, which tend towards routine and possibly deskilled work. Typing is a prime example. It is possible that this is changing through computerization, which is extensive but also equally distributed by gender. Does the wage premium, which use of a computer has been found to confer on users, benefit women sufficiently to suggest some sort of equalization through technology, or possibly even a female advantage? This is tested using data from four European countries. There is no across-the-board benefit from the use of computers. For both men and women it depends on the nature of their occupation. Some, more routine usages of computers are associated with a negative outcome. However, this occupational balance itself varies by gender.

  12. The combined use of Building Information Modelling (BIM) and Unmanned Aerial Vehicle (UAV) technologies for the 3D illustration of the progress of works in infrastructure construction projects

    NASA Astrophysics Data System (ADS)

    Vacanas, Yiannis; Themistocleous, Kyriacos; Agapiou, Athos; Hadjimitsis, Diofantos

    2016-08-01

    Building Information Modelling (BIM) technology is already part of the construction industry and is considered by professionals as a very useful tool for all phases of a construction project. BIM technology, with the particularly useful 3D illustrations which it provides, can be used to illustrate and monitor the progress of works effectively through the entire lifetime of the project. Unmanned Aerial Vehicles (UAVs) have undergone significant advances in equipment capabilities and now have the capacity to acquire high resolution imagery from different angles in a cost effective and efficient manner. By using photogrammetry, characteristics such as distances, areas, volumes, elevations, object sizes, and object shape can be determined within overlapping areas. This paper explores the combined use of BIM and UAV technologies in order to achieve efficient and accurate as-built data collection and 3D illustrations of the works progress during an infrastructure construction project.

  13. Eight Skills in Future Work

    ERIC Educational Resources Information Center

    Weng, Wenting

    2015-01-01

    This article elaborates eight skills in future work which are based on three main changes and are available to different domains of professions. The first change is an increasing technological world for the future. Technology becomes a part of human being's life and affects people's daily life. Mastering relevant competences is necessary to boost…

  14. Technology in Use

    ERIC Educational Resources Information Center

    Glazner, Steve, Comp.

    2012-01-01

    Technology touches people's lives virtually every second of the day. The work world is especially rich with changing technologies, new innovations, and continually revised processes for greater effectiveness and efficiency. One could easily say that a boiler is a boiler, or a carpet is a carpet, but the reality is that all components of all the…

  15. Globalization, technological changes and the search for a new paradigm for women's work.

    PubMed

    Mitter, S

    1999-01-01

    This paper comments on a conceptual paradigm that illustrates the context of the opportunities and challenges that the current technology-led globalization has brought to women's employment in Asia. The UN University Institute for New Technologies project provides the basis for this framework/paradigm. This paradigm helps in analyzing the consequences of an emerging techno-economic order that is imported and does not take into account the specific needs of women. It also acknowledged the liberating aspects of new technologies and modernization. At the same time, it emphasizes the role of the state, the family, and women workers' organizations in counteracting the negative consequences of current globalization. Finally, the paradigm was predicated on the belief that technologies, indigenous or foreign, are appropriate so long as women concerned are given a voice in their countries' policy dialogue.

  16. Heart Work

    ERIC Educational Resources Information Center

    Madden, Sandra R.; Gonzales, Alicia C.

    2017-01-01

    It is not every day that a former student greets a teacher with, "Your course changed my life." The authors are the professor and student of the transformative course. Alicia Gonzales wanted to understand how to work with students to co-construct an environment where persistent problem solving in a technologically rich classroom was the…

  17. Working Together: A Literature Review of Campus Information Technology Partnerships

    ERIC Educational Resources Information Center

    Exline, Eleta

    2009-01-01

    This article reviews the recent literature about the essential but often uneasy alliances made between content experts (archivists and librarians) and technology experts. Differing professional cultures, misunderstandings of one another, limited abilities to envision change, and lack of support from top-level administrators are the most often…

  18. Social Touch Technology: A Survey of Haptic Technology for Social Touch.

    PubMed

    Huisman, Gijs

    2017-01-01

    This survey provides an overview of work on haptic technology for social touch. Social touch has been studied extensively in psychology and neuroscience. With the development of new technologies, it is now possible to engage in social touch at a distance or engage in social touch with artificial social agents. Social touch research has inspired research into technology mediated social touch, and this line of research has found effects similar to actual social touch. The importance of haptic stimulus qualities, multimodal cues, and contextual factors in technology mediated social touch is discussed. This survey is concluded by reflecting on the current state of research into social touch technology, and providing suggestions for future research and applications.

  19. Challenges Facing Group Work Online

    ERIC Educational Resources Information Center

    Chang, Bo; Kang, Haijun

    2016-01-01

    Online group work can be complicated because of its asynchronous characteristics and lack of physical presence, and its requirements for skills in handling technology, human relationships, and content-related tasks. This study focuses on the administrative, logistical and relationship-related challenges in online group work. Challenges in areas…

  20. Distance and Online Social Work Education: Novel Ethical Challenges

    ERIC Educational Resources Information Center

    Reamer, Frederic G.

    2013-01-01

    Digital technology has transformed social work education. Today's students can take individual courses and earn an entire degree without ever meeting their faculty members in person. Technological innovations such as videoconferencing, live online chat, asynchronous podcasts, and webinars enable social work educators to reach students whose…

  1. Work Organization, Technology, and Performance in Customer Service and Sales.

    ERIC Educational Resources Information Center

    Batt, Rosemary

    1999-01-01

    Performance data on 223 customer-service and sales representatives showed that participation in self-managed teams correlated with significant improvement in service quality and 9.3% sales increase. New technology helped teams increase sales 17.4%. Total-quality management did not affect performance. Results show that group collaboration fosters…

  2. Type A behavior and work situation: associations with burnout and work engagement.

    PubMed

    Hallberg, Ulrika E; Johansson, Gunn; Schaufeli, Wilmar B

    2007-04-01

    The aim of the present study was to investigate Type A behavior as well as perceived work situation, and associations with burnout and work engagement. The associations in focus were investigated through hierarchical regressions in a sample (N= 329) of Swedish Information Communication Technology consultants. The findings indicated that both work situation and Type A behavior was correlated with work engagement and burnout; however, no interactions between Type A behavior and work situation were elicited. The main conclusion was that the achievement striving aspect of Type A behavior appears as "non-toxic" and is related only to work engagement. However, the irritability/impatience aspect appears to be responsible for burnout complaints among Type A individuals, possibly through negative effects of the mood itself than through perceived stress at work.

  3. Work organization and ergonomics.

    PubMed

    Carayon, P; Smith, M J

    2000-12-01

    This paper examines the impact of sociotechnical and business trends on work organization and ergonomics. This analysis is performed with the use of Balance Theory (Smith and Carayon-Sainfort, Int. J. Ind. Ergon. 1989, 4, 67-79). The impact on work organization and the work system of the following sociotechnical and business trends is discussed: re-structuring and re-organizing of companies, new forms of work organization, workforce diversity, and information and communication technology. An expansion of Balance Theory, from the design of work systems to the design of organizations, is discussed. Finally, the issue of change is examined. Several elements and methods are discussed for the design of change processes.

  4. Temperate forest fragments maintain aboveground carbon stocks out to the forest edge despite changes in community composition.

    PubMed

    Ziter, Carly; Bennett, Elena M; Gonzalez, Andrew

    2014-11-01

    Edge effects are among the primary mechanisms by which forest fragmentation can influence the link between biodiversity and ecosystem processes, but relatively few studies have quantified these mechanisms in temperate regions. Carbon storage is an important ecosystem function altered by edge effects, with implications for climate change mitigation. Two opposing hypotheses suggest that aboveground carbon (AGC) stocks at the forest edge will (a) decrease due to increased tree mortality and compositional shifts towards smaller, lower wood density species (e.g., as seen in tropical systems) or, less often, (b) increase due to light/temperature-induced increases in diversity and productivity. We used field-based measurements, allometry, and mixed models to investigate the effects of proximity to the forest edge on AGC stocks, species richness, and community composition in 24 forest fragments in southern Quebec. We also asked whether fragment size or connectivity with surrounding forests altered these edge effects. AGC stocks remained constant across a 100 m edge-to-interior gradient in all fragment types, despite changes in tree community composition and stem density consistent with expectations of forest edge effects. We attribute this constancy primarily to compensatory effects of small trees at the forest edge; however, it is due in some cases to the retention of large trees at forest edges, likely a result of forest management. Our results suggest important differences between temperate and tropical fragments with respect to mechanisms linking biodiversity and AGC dynamics. Small temperate forest fragments may be valuable in conservation efforts based on maintaining biodiversity and multiple ecosystem services.

  5. BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo

    PubMed Central

    Sapkota, Gopal P.; Cummings, Lorna; Newell, Felicity S.; Armstrong, Christopher; Bain, Jennifer; Frodin, Morten; Grauert, Matthias; Hoffmann, Matthias; Schnapp, Gisela; Steegmaier, Martin; Cohen, Philip; Alessi, Dario R.

    2006-01-01

    Hormones and growth factors induce the activation of a number of protein kinases that belong to the AGC subfamily, including isoforms of PKA, protein kinase B (also known as Akt), PKC, S6K p70 (ribosomal S6 kinase), RSK (p90 ribosomal S6 kinase) and MSK (mitogen- and stress-activated protein kinase), which then mediate many of the physiological processes that are regulated by these extracellular agonists. It can be difficult to assess the individual functions of each AGC kinase because their substrate specificities are similar. Here we describe the small molecule BI-D1870, which inhibits RSK1, RSK2, RSK3 and RSK4 in vitro with an IC50 of 10–30 nM, but does not signi-ficantly inhibit ten other AGC kinase members and over 40 other protein kinases tested at 100-fold higher concentrations. BI-D1870 is cell permeant and prevents the RSK-mediated phorbol ester- and EGF (epidermal growth factor)-induced phosphoryl-ation of glycogen synthase kinase-3β and LKB1 in human embry-onic kidney 293 cells and Rat-2 cells. In contrast, BI-D1870 does not affect the agonist-triggered phosphorylation of substrates for six other AGC kinases. Moreover, BI-D1870 does not suppress the phorbol ester- or EGF-induced phosphorylation of CREB (cAMP-response-element-binding protein), consistent with the genetic evidence indicating that MSK, and not RSK, isoforms mediate the mitogen-induced phosphorylation of this transcription factor. PMID:17040210

  6. Critical role of the axonal guidance cue EphrinB2 in lung growth, angiogenesis, and repair.

    PubMed

    Vadivel, Arul; van Haaften, Tim; Alphonse, Rajesh S; Rey-Parra, Gloria-Juliana; Ionescu, Lavinia; Haromy, Al; Eaton, Farah; Michelakis, Evangelos; Thébaud, Bernard

    2012-03-01

    Lung diseases characterized by alveolar damage currently lack efficient treatments. The mechanisms contributing to normal and impaired alveolar growth and repair are incompletely understood. Axonal guidance cues (AGC) are molecules that guide the outgrowth of axons to their targets. Among these AGCs, members of the Ephrin family also promote angiogenesis, cell migration, and organogenesis outside the nervous system. The role of Ephrins during alveolar growth and repair is unknown. We hypothesized that EphrinB2 promotes alveolar development and repair. We used in vitro and in vivo manipulation of EphrinB2 signaling to assess the role of this AGC during normal and impaired lung development. In vivo EphrinB2 knockdown using intranasal siRNA during the postnatal stage of alveolar development in rats arrested alveolar and vascular growth. In a model of O(2)-induced arrested alveolar growth in newborn rats, air space enlargement, loss of lung capillaries, and pulmonary hypertension were associated with decreased lung EphrinB2 and receptor EphB4 expression. In vitro, EphrinB2 preserved alveolar epithelial cell viability in O(2), decreased O(2)-induced alveolar epithelial cell apoptosis, and accelerated alveolar epithelial cell wound healing, maintained lung microvascular endothelial cell viability, and proliferation and vascular network formation. In vivo, treatment with intranasal EphrinB2 decreased alveolar epithelial and endothelial cell apoptosis, preserved alveolar and vascular growth in hyperoxic rats, and attenuated pulmonary hypertension. The AGC EphrinB2 may be a new therapeutic target for lung repair and pulmonary hypertension.

  7. Technology Integration: A Best Practice Perspective

    ERIC Educational Resources Information Center

    Lesisko, Lee J.; Wright, Robert J.; O'Hern, Brenda

    2010-01-01

    The technology coordinator has the responsibility of collaborating with school leaders and educators to integrate technology into the curriculum and operations of the school. Not only does this individual have to understand how technology works, but also must determine the best way to infuse it in a school setting. Technology leaders must possess…

  8. Technology and teen drivers.

    PubMed

    Lee, John D

    2007-01-01

    The rapid evolution of computing, communication, and sensor technology is likely to affect young drivers more than others. The distraction potential of infotainment technology stresses the same vulnerabilities that already lead young drivers to crash more frequently than other drivers. Cell phones, text messaging, MP3 players, and other nomadic devices all present a threat because young drivers may lack the spare attentional capacity for vehicle control and the ability to anticipate and manage hazards. Moreover, young drivers are likely to be the first and most aggressive users of new technology. Fortunately, emerging technology can also support safe driving. Electronic stability control, collision avoidance systems, intelligent speed adaptation, and vehicle tracking systems can all help mitigate the threats to young drivers. However, technology alone is unlikely to make young drivers safer. One promising approach to tailoring technology to teen drivers is to extend proven methods for enhancing young driver safety. The success of graduated drivers license programs (GDL) and the impressive safety benefit of supervised driving suggest ways of tailoring technology to the needs of young drivers. To anticipate the effects of technology on teen driving it may be useful to draw an analogy between the effects of passengers and the effects of technology. Technology can act as a teen passenger and undermine safety or it can act as an adult passenger and enhance safety. Rapidly developing technology may have particularly large effects on teen drivers. To maximize the positive effects and minimize the negative effects will require a broad range of industries to work together. Ideally, vehicle manufacturers would work with infotainment providers, insurance companies, and policy makers to craft new technologies so that they accommodate the needs of young drivers. Without such collaboration young drivers will face even greater challenges to their safety as new technologies emerge.

  9. [Application of multiple-attribute utility technology (MAUT) to decisions about a work-site stress-control intervention for public-sector office workers].

    PubMed

    Hagihara, Akihito; Tarumi, Kimio

    2013-01-01

    The reasons behind the establishment of particular health-promotion programs in community or work settings are often unclear, and such programs are rarely evaluated from a broad perspective after they are implemented. Thus, multiattribute utility technology (MAUT) was used to design a work-site stress-control program. The sample consisted of public-sector workers in B City in Japan. Stakeholders in the work-site stress-control program included employers (municipal authorities), employees (public workers), and healthcare personnel. Six goals and three strategies (i.e., personnel, self-care, and staff) related to stress-control programs were considered. The results showed that the self-care strategy received the highest score for overall utility (i.e., 96.2), and the overall-utility score for the remaining two strategies was approximately 70. The self-care strategy emerged as the most useful of the three strategies for developing a stress-control program in a target work place. The application of MAUT may be useful for developing an effective stress-control program in occupational settings.

  10. Cross-sectional associations between daily rest periods during weekdays and psychological distress, non-restorative sleep, fatigue, and work performance among information technology workers.

    PubMed

    Tsuchiya, Masao; Takahashi, Masaya; Miki, Keiichi; Kubo, Tomohide; Izawa, Shuhei

    2017-04-07

    A daily rest period (DRP; rest taken from daily work during a 24 h period), is essential to work recovery. This study examined DRPs' distribution and association with health outcomes among information technology workers recruited from an internet panel (N=1,811). Participants completed a web questionnaire examining psychological distress as a primary outcome, along with non-restorative sleep, fatigue (stress reaction), and work performance. Logistic regression analysis showed elevated psychological distress when DRP was <12 h (OR: 2.54; 95% CI: 1.47-4.42) and <11 h (OR: 2.48, 95% CI: 1.17-5.26), although the 95% CI included 1 after adjusting for age, sex, and working and commuting hours. After the above adjustment, similar associations were found with non-restorative sleep and fatigue, but not work performance, when DRP was <12 h. These findings constitute the first analysis of a dose-response relationship between DRP and subjective health outcomes among white-collar workers.

  11. Prolonged action potential duration in cardiac ablation of PDK1 mice.

    PubMed

    Han, Zhonglin; Jiang, Yu; Yang, Zhongzhou; Cao, Kejiang; Wang, Dao W

    2015-01-01

    The involvement of the AGC protein kinase family in regulating arrhythmia has drawn considerable attention, but the underlying mechanisms are still not clear. The aim of this study is to explore the role of 3-phosphoinositide-dependent protein kinase-1 (PDK1), one of upstream protein kinases of the AGC protein kinase family, in the pathogenesis of dysregulated electrophysiological basis. PDK1(F/F) αMHC-Cre mice and PDK1(F/F) mice were divided into experiment group and control group. Using patch clamping technology, we explored action potential duration in both groups, and investigated the functions of transient outward potassium channel and L-type Ca(2+) channel to explain the abnormal action potential duration. Significant prolongation action potential duration was found in mice with PDK1 deletion. Further, the peak current of transient outward potassium current and L-type Ca(2+) current were decreased by 84% and 49% respectively. In addition, dysregulation of channel kinetics lead to action potential duration prolongation further. In conclusion, we have demonstrated that PDK1 participates in action potential prolongation in cardiac ablation of PDK1 mice. This effect is likely to be mediated largely through downregulation of transient outward potassium current. These findings indicate the modulation of the PDK1 pathway could provide a new mechanism for abnormal electrophysiological basis.

  12. Space Technology for the New Century

    NASA Technical Reports Server (NTRS)

    1998-01-01

    The National Aeronautics and Space Administration (NASA) is responsible for developing advanced space technologies that will lower the cost and improve the performance of existing space activities and enable new ones. Although NASA has recently proved adept at incorporating modern technologies into its spacecraft, the agency currently supports relatively little work in long-term space technology development. To enable ambitious future space activities and to achieve its long-term goals, NASA needs to engage in space research and technology development (R&T) in critical areas for the long term. NASA requested that the National Research Council (NRC) examine the nation's space technology needs in the post-2000 time frame and identify high-risk, high-payoff technology that could improve the capabilities and reduce the costs fo NASA, other government, and commercial space programs. The NRC was also asked to suggest how NASA can work more effectively with industry and universities to develop these technologies. To accomplish these ends, the Committee on Advanced Space Technology, under the auspices of the Aeronautics and Space Engineering Board, undertook a systematic process of information gathering and technology assessment. Six key technologies that the committee believes NASA should support are presented.

  13. High-Tech, Hard Work: An Investigation of Teachers' Work in the Digital Age

    ERIC Educational Resources Information Center

    Selwyn, Neil; Nemorin, Selena; Johnson, Nicola

    2017-01-01

    This paper explores the ways in which digital technologies are now implicated in the work--and specifically the labour--of school teachers. Drawing upon qualitative studies in two Australian high schools, the paper examines the variety of ways in which teachers' work is now enacted and experienced along digital lines. In particular, the paper…

  14. Understanding attitudes toward information and communication technology in home-care: Information and communication technology as a market good within Norwegian welfare services.

    PubMed

    Øyen, Karianne Røssummoen; Sunde, Olivia Sissil; Solheim, Marit; Moricz, Sara; Ytrehus, Siri

    2018-09-01

    The aim of this study was to better understand nurses' and other staff members' attitudes toward the usefulness of information and communication technology in home-care settings. Research has found that beliefs about the expected benefits of information and communication technology impact the use of technology. Furthermore, inexperience with using information and communication technology may cause negative attitudes. This article is based on a questionnaire to 155 nurses and other staff members in home-care in Sogn og Fjordane county in Norway. The results revealed minimal use of information and communication technology at work; however, participants had positive attitudes regarding the potential benefits of information and communication technology use in home-care. Individuals' extensive use of and familiarity with different solutions in private lives could be an important context for explaining employees' attitudes. Given that information and communication technology is both a welfare service and a market good, this may explain individuals' positive attitudes toward information and communication technology despite their lack of experience with it at work. Experiences with information and communication technology as a market good and the way new technologies can affect work routines will affect the implementation of information and communication technology in home-care.

  15. Libraries and Technology.

    ERIC Educational Resources Information Center

    The Bookmark, 1988

    1988-01-01

    The 15 papers in this issue report on important aspects of work done by the Statewide Automation Committee (SAC) in preparing the current strategic plan for the use of new technologies by the libraries of New York State, and on some of the innovative uses of technology that the plan seeks to foster and facilitate. The range of the papers reflects…

  16. Real-Time Charging Strategies for an Electric Vehicle Aggregator to Provide Ancillary Services

    DOE PAGES

    Wenzel, George; Negrete-Pincetic, Matias; Olivares, Daniel E.; ...

    2017-03-13

    Real-time charging strategies, in the context of vehicle to grid (V2G) technology, are needed to enable the use of electric vehicle (EV) fleets batteries to provide ancillary services (AS). Here, we develop tools to manage charging and discharging in a fleet to track an Automatic Generation Control (AGC) signal when aggregated. We also propose a real-time controller that considers bidirectional charging efficiency and extend it to study the effect of looking ahead when implementing Model Predictive Control (MPC). Simulations show that the controller improves tracking error as compared with benchmark scheduling algorithms, as well as regulation capacity and battery cycling.

  17. Real-Time Charging Strategies for an Electric Vehicle Aggregator to Provide Ancillary Services

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wenzel, George; Negrete-Pincetic, Matias; Olivares, Daniel E.

    Real-time charging strategies, in the context of vehicle to grid (V2G) technology, are needed to enable the use of electric vehicle (EV) fleets batteries to provide ancillary services (AS). Here, we develop tools to manage charging and discharging in a fleet to track an Automatic Generation Control (AGC) signal when aggregated. We also propose a real-time controller that considers bidirectional charging efficiency and extend it to study the effect of looking ahead when implementing Model Predictive Control (MPC). Simulations show that the controller improves tracking error as compared with benchmark scheduling algorithms, as well as regulation capacity and battery cycling.

  18. MSFC Technology Year in Review 2015

    NASA Technical Reports Server (NTRS)

    Reynolds, David; Tinker, Mike

    2015-01-01

    MSFC has a strong diverse portfolio of technology development projects, ranging from flight projects to very low Technology Readiness Level (TRL) laboratory projects. The 2015 Year in Review highlights the Center's technology projects and celebrates their accomplishments to raise awareness of technology development work that is integral to the success of future Agency flight programs.

  19. Improving Evaluation to Address the Unintended Consequences of Health Information Technology:. a Position Paper from the Working Group on Technology Assessment & Quality Development.

    PubMed

    Magrabi, F; Ammenwerth, E; Hyppönen, H; de Keizer, N; Nykänen, P; Rigby, M; Scott, P; Talmon, J; Georgiou, A

    2016-11-10

    With growing use of IT by healthcare professionals and patients, the opportunity for any unintended effects of technology to disrupt care health processes and outcomes is intensified. The objectives of this position paper by the IMIA Working Group (WG) on Technology Assessment and Quality Development are to highlight how our ongoing initiatives to enhance evaluation are also addressing the unintended consequences of health IT. Review of WG initiatives Results: We argue that an evidence-based approach underpinned by rigorous evaluation is fundamental to the safe and effective use of IT, and for detecting and addressing its unintended consequences in a timely manner. We provide an overview of our ongoing initiatives to strengthen study design, execution and reporting by using evaluation frameworks and guidelines which can enable better characterization and monitoring of unintended consequences, including the Good Evaluation Practice Guideline in Health Informatics (GEP-HI) and the Statement on Reporting of Evaluation Studies in Health Informatics (STARE-HI). Indicators to benchmark the adoption and impact of IT can similarly be used to monitor unintended effects on healthcare structures, processes and outcome. We have also developed EvalDB, a web-based database of evaluation studies to promulgate evidence about unintended effects and are developing the content for courses to improve training in health IT evaluation. Evaluation is an essential ingredient for the effective use of IT to improve healthcare quality and patient safety. WG resources and skills development initiatives can facilitate a proactive and evidence-based approach to detecting and addressing the unintended effects of health IT.

  20. Reimagining the Role of Technology in Education: 2017 National Education Technology Plan Update

    ERIC Educational Resources Information Center

    Office of Educational Technology, US Department of Education, 2017

    2017-01-01

    The National Education Technology Plan (NETP) sets a national vision and plan for learning enabled by technology through building on the work of leading education researchers; district, school, and higher education leaders; classroom teachers; developers; entrepreneurs; and nonprofit organizations. The principles and examples provided in this…

  1. The alfalfa “almost darks” campaign: Pilot VLA HI observations of five high mass-to-light ratio systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cannon, John M.; Martinkus, Charlotte P.; Leisman, Lukas

    We present new Very Large Array (VLA) H i spectral line imaging of five sources discovered by the ALFALFA extragalactic survey. These targets are drawn from a larger sample of systems that were not uniquely identified with optical counterparts during ALFALFA processing, and as such have unusually high H i mass to light ratios. The candidate “Almost Dark” objects fall into four broad categories: (1) objects with nearby H i neighbors that are likely of tidal origin; (2) objects that appear to be part of a system of multiple H i sources, but which may not be tidal in origin;more » (3) objects isolated from nearby ALFALFA H i detections, but located near a gas-poor early type galaxy; (4) apparently isolated sources, with no object of coincident redshift within ∼400 kpc. Roughly 75% of the 200 objects without identified counterparts in the α.40 database (Haynes et al. 2011) fall into category 1 (likely tidal), and were not considered for synthesis follow-up observations. The pilot sample presented here (AGC193953, AGC208602, AGC208399, AGC226178, and AGC233638) contains the first five sources observed as part of a larger effort to characterize H i sources with no readily identifiable optical counterpart at single dish resolution (3.′5). These objects span a range of H i mass [7.41 < log(M{sub Hi}) < 9.51] and H i mass to B-band luminosity ratios (3 < M{sub Hi}/L{sub B} < 9). We compare the H i total intensity and velocity fields to optical imaging drawn from the Sloan Digital Sky Survey and to ultraviolet imaging drawn from archival GALEX observations. Four of the sources with uncertain or no optical counterpart in the ALFALFA data are identified with low surface brightness optical counterparts in Sloan Digital Sky Survey imaging when compared with VLA H i intensity maps, and appear to be galaxies with clear signs of ordered rotation in the H i velocity fields. Three of these are detected in far-ultraviolet GALEX images, a likely indication of star formation

  2. The Acasta Gneiss - a Hadean cratonic nucleus

    NASA Astrophysics Data System (ADS)

    Sprung, P.; Scherer, E. E.; Maltese, A.; Bast, R.; Bleeker, W.; Mezger, K.

    2016-12-01

    The known terrestrial rock record lacks undisputed, chemically intact Hadean crust. Direct evidence from this eon has been restricted to zircon grains within younger rocks [1]. The Acasta Gneiss Complex (AGC; NT, CA) has yielded zircon with Hadean domains [e.g., 2,3], but the time at which AGC rocks became closed chemical systems is unclear [4,5]. Determining this `time of last disturbance' (tld) would provide a minimum protolith age, and is crucial for using radiogenic isotope compositions of bulk rocks to trace crust-mantle evolution. Recent studies mostly focused on the `low-strain' eastern AGC [e.g., 6, 7], which records an evolving, early-mid Archean cratonic nucleus [7]. We also studied the `high-strain' banded gneiss in the western AGC, which hosts >4 Ga zircon domains [2,3], too. Our focusing lay on adjoining, lithologically distinct bands [8] of two distinct chemical groups: A) Mafic, chondrite-normalized LaN/YbN ≦20, slightly HFSE- depleted, and B) TTG-like, LaN/YbN up to 145, markedly HFSE-depleted. Six adjacent bands yield a well-defined 4 Ga Sm-Nd isochron with a ɛNd4Ga of +2 and ɛHf4Ga values from +1 to +6. Within-band Sm-Nd and Lu-Hf systematics imply younger mineral re-equilibration [9]. We interpret the 4 Ga Sm-Nd isochron to date the physical juxtaposition of bands in the gneiss unit and to define tld among bands for elements less mobile and diffusive than Sm and Nd. Contrasting Sm-Nd results from the same unit [10] likely are due to sampling at too fine a scale. Digestion of metamict pre-tld zircon likely caused the scatter in Lu-Hf. Both decay systems hint at the existence of a possibly local, strongly depleted Hadean mantle domain. The TTG-like bands are 0.4 Gyr older than similar rocks in the `low-strain' eastern AGC [7]. The AGC was thus an evolved cratonic nucleus already at 4 Ga, possibly with a depleted lithospheric keel. [1] Cavosie et al. (2004) Prec. Res. 135, 251-279 [2] Bowring & Williams (1999) CMP 134, 3-16 [3] Iizuka et al

  3. Large Deployable Reflector Science and Technology Workshop. Volume 3: Systems and Technology Assessment

    NASA Technical Reports Server (NTRS)

    Leidich, C. A. (Editor); Pittman, R. B. (Editor)

    1984-01-01

    The results of five technology panels which convened to discuss the Large Deployable Reflector (LDR) are presented. The proposed LDR is a large, ambient-temperature, far infrared/submillimeter telescope designed for space. Panel topics included optics, materials and structures, sensing and control, science instruments, and systems and missions. The telescope requirements, the estimated technology levels, and the areas in which the generic technology work has to be augmented are enumerated.

  4. SHARED TECHNOLOGY TRANSFER PROGRAM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    GRIFFIN, JOHN M. HAUT, RICHARD C.

    2008-03-07

    The program established a collaborative process with domestic industries for the purpose of sharing Navy-developed technology. Private sector businesses were educated so as to increase their awareness of the vast amount of technologies that are available, with an initial focus on technology applications that are related to the Hydrogen, Fuel Cells and Infrastructure Technologies (Hydrogen) Program of the U.S. Department of Energy. Specifically, the project worked to increase industry awareness of the vast technology resources available to them that have been developed with taxpayer funding. NAVSEA-Carderock and the Houston Advanced Research Center teamed with Nicholls State University to catalog NAVSEA-Carderockmore » unclassified technologies, rated the level of readiness of the technologies and established a web based catalog of the technologies. In particular, the catalog contains technology descriptions, including testing summaries and overviews of related presentations.« less

  5. TRAINING OLDER WORKERS FOR TECHNOLOGY-BASED EMPLOYMENT.

    PubMed

    Lee, Chin Chin; Czaja, Sara J; Sharit, Joseph

    2009-01-01

    An increasingly aging workforce and advances in technology are changing work environments and structures. The continued employability of older adults, particularly those of lower socioeconomic status (SES), requires them to participate in training programs to ensure their competence in today's workplace. Focus groups with 37 unemployed adults (51-76 years old) were conducted to gather information about barriers and obstacles for returning to work, training needs and formats, work experiences, and perceptions of the characteristics of an ideal job. Overall, results indicated that participants experienced age discrimination and lack of technology skills. They also expressed a desire to receive additional training on technology and a preference for classroom training.

  6. Biosensor technology for the detection of illegal drugs I: objectives, preparatory work, and drug enrichment

    NASA Astrophysics Data System (ADS)

    Hilpert, Reinhold; Binder, Florian; Grol, Michael; Hallermayer, Klaus; Josel, Hans-Peter; Klein, Christian; Maier, Josef; Oberpriller, Helmut; Ritter, Josef; Scheller, Frieder W.

    1994-10-01

    In a joint project of Deutsche Aerospace, Boehringer Mannheim and the University of Potsdam portable devices for the detection of illegal drugs, based on biosensor technology, are being developed. The concept enrichment of the drug from the gas phase and detection by immunological means. This publication covers the description of our objectives, preparatory work and results concerning enrichment of drugs from the gas phase. Vapor pressures of cocaine and cannabinoids have been determined. A test gas generator has been constructed which allows for reproducible preparation of cocaine concentrations between 2 ng/l and 2 pg/l. Coupling of a thermodesorption unit with GC/MS has been established for reference analysis. As another analytical tool, an ELISA with a lower detection limit of about 0,5 pg cocaine/assay has been developed. Applying fleece-type adsorbers, enrichment factors for cocaine in the range of 105 have been realized. No significant interference was found with potentially disturbing substances.

  7. Comparison of Fast Neutron Detector Technologies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stange, Sy; Mckigney, Edward Allen

    2015-02-09

    This report documents the work performed for the Department of Homeland Security Domestic Nuclear Detection O ce as the project Fast Neutron Detection Evaluation under contract HSHQDC-14-X-00022. This study was performed as a follow-on to the project Study of Fast Neutron Signatures and Measurement Techniques for SNM Detection - DNDO CFP11-100 STA-01. That work compared various detector technologies in a portal monitor con guration, focusing on a comparison between a number of fast neutron detection techniques and two standard thermal neutron detection technologies. The conclusions of the earlier work are contained in the report Comparison of Fast Neutron Detector Technologies.more » This work is designed to address questions raised about assumptions underlying the models built for the earlier project. To that end, liquid scintillators of two di erent sizes{ one a commercial, o -the-shelf (COTS) model of standard dimensions and the other a large, planer module{were characterized at Los Alamos National Laboratory. The results of those measurements were combined with the results of the earlier models to gain a more complete picture of the performance of liquid scintillator as a portal monitor technology.« less

  8. Virtual Teams and Human Work Interaction Design - Learning to Work in and Designing for Virtual Teams

    NASA Astrophysics Data System (ADS)

    Orngreen, Rikke; Clemmensen, Torkil; Pejtersen, Annelise Mark

    The boundaries and work processes for how virtual teams interact are undergoing changes, from a tool and stand-alone application orientation, to the use of multiple generic platforms chosen and redesigned to the specific context. These are often at the same time designed both by professional software developers and the individual members of the virtual teams, rather than determined on a single organizational level. There may be no impact of the technology per se on individuals, groups or organizations, as the technology for virtual teams rather enhance situation ambiguity and disrupt existing task-artifact cycles. This ambiguous situation calls for new methods for empirical work analysis and interaction design that can help us understand how organizations, teams and individuals learn to organize, design and work in virtual teams in various networked contexts.

  9. NASA scheduling technologies

    NASA Technical Reports Server (NTRS)

    Adair, Jerry R.

    1994-01-01

    This paper is a consolidated report on ten major planning and scheduling systems that have been developed by the National Aeronautics and Space Administration (NASA). A description of each system, its components, and how it could be potentially used in private industry is provided in this paper. The planning and scheduling technology represented by the systems ranges from activity based scheduling employing artificial intelligence (AI) techniques to constraint based, iterative repair scheduling. The space related application domains in which the systems have been deployed vary from Space Shuttle monitoring during launch countdown to long term Hubble Space Telescope (HST) scheduling. This paper also describes any correlation that may exist between the work done on different planning and scheduling systems. Finally, this paper documents the lessons learned from the work and research performed in planning and scheduling technology and describes the areas where future work will be conducted.

  10. Ethical Applications of Technology in HRD

    ERIC Educational Resources Information Center

    Lin, Hong

    2006-01-01

    Human resource development (HRD) professionals are increasingly incorporating technology into their work activities. However, research that examines the ethics in the use of technology by HRD professionals is still underrepresented in the literature. This article first conducts a PEST (political, economic, social-cultural, and technological)…

  11. Revitalized militarily critical technologies program

    NASA Astrophysics Data System (ADS)

    Wick, Raymond V.

    2005-04-01

    The Department of Defense (DoD) Militarily Critical Technologies Program (MCTP) provides a systematic, ongoing assessment and analysis of goods and technologies to determine those that would permit significant advances in the development, production and use of military capabilities of potential adversaries and those that are being developed worldwide that have the potential to significantly enhance or degrade US military capabilities in the future. The program's objective is to characterize the technologies, including quantitative values and parameters, and assess worldwide technology capabilities. The MCTP is composed of two sets of documents, the well known and often referenced one, the MCTL, and a second one, a more recently added list called the Developing Science and Technologies List (DSTL). Both are products of the MCTP process, however, the later is primarily used by DDR&E and other government organizations and agencies to aid in the prioritization and understanding of new technologies being developed worldwide. Technologies are selected for the MCTL and the DSTL through the deliberation and consensus of Technology Working Groups (TWGs). TWGs continually screen technologies and nominate items to be added or removed from the MCTL and the DSTL as appropriate. Working within an informal structure, TWG members are composed of government, industry and academia subject matter experts, who strive to produce precise and objective analyses across each technology areas. This process and details of the current MCTP are outlined in this poster paper. This paper focuses on the solid state laser technology area, using it as an example of the MCTP's product of assessing, identifying, and quantifying militarily critical technology parameters.

  12. Technology and the Politics of Change at Work: The Case of Dalebake Bakeries.

    ERIC Educational Resources Information Center

    Dawson, Patrick; Gunson, Nicky

    2002-01-01

    A case study of automation in the British baking industry illustrates several perspectives: (1) technological change as inevitable due to external market forces; (2) selection and implementation of technology as an outcome of strategic choices; and (3) awareness of the need for change as part of a political process in which choices are made among…

  13. NASA AETC Test Technology Subproject

    NASA Technical Reports Server (NTRS)

    Bell, James

    2017-01-01

    Funds directed to improve measurement capabilities (pressure, force, flow, and temperature), test techniques and processes, and develop technologies critical to meeting NASA research needs and applicable to a multitude of facilities. Primarily works by funding small ($40K - $400K) tasks which result in a demonstration or initial capability of a new technology in an AETC facility.TT research and development tasks are generally TRL 3-6; they should be things which work in small scale or lab environments but need further development for use in production facilities.TT differs from CA in its focus on smaller-scale tasks and on instrumentation. Technologies developed by TT may become CA projects in order be fully realized within a facility.

  14. Technology Games: Using Wittgenstein for Understanding and Evaluating Technology.

    PubMed

    Coeckelbergh, Mark

    2017-08-15

    In the philosophy of technology after the empirical turn, little attention has been paid to language and its relation to technology. In this programmatic and explorative paper, it is proposed to use the later Wittgenstein, not only to pay more attention to language use in philosophy of technology, but also to rethink technology itself-at least technology in its aspect of tool, technology-in-use. This is done by outlining a working account of Wittgenstein's view of language (as articulated mainly in the Investigations) and by then applying that account to technology-turning around Wittgenstein's metaphor of the toolbox. Using Wittgenstein's concepts of language games and form of life and coining the term 'technology games', the paper proposes and argues for a use-oriented, holistic, transcendental, social, and historical approach to technology which is empirically but also normatively sensitive, and which takes into account implicit knowledge and know-how. It gives examples of interaction with social robots to support the relevance of this project for understanding and evaluating today's technologies, makes comparisons with authors in philosophy of technology such as Winner and Ihde, and sketches the contours of a phenomenology and hermeneutics of technology use that may help us to understand but also to gain a more critical relation to specific uses of concrete technologies in everyday contexts. Ultimately, given the holism argued for, it also promises a more critical relation to the games and forms of life technologies are embedded in-to the ways we do things.

  15. Automation Technology in Elementary Technology Education.

    ERIC Educational Resources Information Center

    Hiltunen, Jukka; Jarvinen, Esa-Matti

    2000-01-01

    Finnish fifth-graders (n=20) and sixth-graders (n=23) worked in teams in a Lego/Logo-Control Lab to complete Lego design activities. Observations showed that they became familiar with automation technology but their skills were not always up to their ideas. Activities based on real-life situations gave them ownership and engaged them in learning.…

  16. ENVIRONMENTAL TECHNOLOGY REPORT - LEAD DUST WIPE MEASUREMENT TECHNOLOGY MONITORING TECHNOLOGIES INTERNATIONAL, PDV 5000 TRACE ELEMENT ANALYZER

    EPA Science Inventory

    ETV works in partnership with recognized standards and testing organizations and stakeholder groups consisting of regulators, buyers, and vendor organizations, with the full participation of individual technology developers. The program evaluates the performance of innovative

  17. Desktop Technology for Newspapers: Use of the Computer Tool.

    ERIC Educational Resources Information Center

    Wilson, Howard Alan

    This work considers desktop publishing technology as a way used to paginate newspapers electronically, tracing the technology's development from the beginning of desktop publishing in the mid-1980s to the 1990s. The work emphasizes how desktop publishing technology is and can be used by weekly newspapers. It reports on a Pennsylvania weekly…

  18. "Technological Me": Young Children's Use of Technology across Their Home and School Contexts

    ERIC Educational Resources Information Center

    Gronn, Donna; Scott, Anne; Edwards, Susan; Henderson, Michael

    2014-01-01

    Research into children's learning with digital technologies is represented by a growing body of literature examining the relationship between home-school technological practices. A focus of this work is on the notion of a "digital-disconnect" between home and school. This argument suggests that children are such native users of…

  19. Emerging Communication Technologies (ECT) Phase 3 Final Report

    NASA Technical Reports Server (NTRS)

    Bastin, Gary L.; Harris, William G.; Bates, Lakesha D.; Nelson, Richard A.

    2004-01-01

    The Emerging Communication Technology (ECT) project investigated three First Mile communication technologies in support of NASA s Second Generation Reusable Launch Vehicle (2nd Gen RLV), Orbital Space Plane, Advanced Range Technology Working Group (ARTWG) and the Advanced Spaceport Technology Working Group (ASTWG). These First Mile technologies have the purpose of interconnecting mobile users with existing Range Communication infrastructures. ECT was a continuation of the Range Information System Management (RISM) task started in 2002. RISM identified the three advance communication technologies investigated under ECT. These were Wireless Ethernet (Wi-Fi), Free Space Optics (FSO), and Ultra Wideband (UWB). Due to the report s size, it has been broken into three volumes: 1) Main Report 2) Appendices 3) UWB.

  20. Recent trends in assistive technology for mobility

    PubMed Central

    2012-01-01

    Loss of physical mobility makes maximal participation in desired activities more difficult and in the worst case fully prevents participation. This paper surveys recent work in assistive technology to improve mobility for persons with a disability, drawing on examples observed during a tour of academic and industrial research sites in Europe. The underlying theme of this recent work is a more seamless integration of the capabilities of the user and the assistive technology. This improved integration spans diverse technologies, including powered wheelchairs, prosthetic limbs, functional electrical stimulation, and wearable exoskeletons. Improved integration is being accomplished in three ways: 1) improving the assistive technology mechanics; 2) improving the user-technology physical interface; and 3) sharing of control between the user and the technology. We provide an overview of these improvements in user-technology integration and discuss whether such improvements have the potential to be transformative for people with mobility impairments. PMID:22520500

  1. Alternative Work Programs

    ERIC Educational Resources Information Center

    Kuehn, Kerri L.

    2004-01-01

    Employers are feeling the strain of needing to offer alternative work arrangements to retain and recruit employees. Due to a change in demographics, dual-career couples and increased technology; people are demanding a transformation in the workplace environment. Two alternatives, which are being offered by employers, are flextime and…

  2. Technology Education in the Liberal Arts.

    ERIC Educational Resources Information Center

    Wiens, A. Emerson

    1987-01-01

    Reviews development of technological literacy in liberal arts curriculum, especially efforts of Sloan Foundation. Observes that few general education courses with technology content are taught by industrial educators; focus of the new liberal arts is on understanding how technology works; quantitative skills are vital; and social and human…

  3. Visions Management: Effective Teaching through Technology.

    ERIC Educational Resources Information Center

    Larson, Robert W.

    In making effective use of technology, instructors must face several challenges, such as deciding which technology is really necessary for effective teaching and working with limited department budgets. In addressing these issues, faculty should be aware of three major trends in communications technology: miniaturization of the media of…

  4. Gender, Technology, and the History of Technical Communication.

    ERIC Educational Resources Information Center

    Durack, Katherine T.

    1997-01-01

    Considers why women have been absent from the history of technical communication. Discusses research from the history of technology suggesting that notions of "technology,""work," and "workplace" may be gendered terms. Concludes with several suggestions for defining technical communication so that significant works of…

  5. Cyberfeminism, technology, and international "development".

    PubMed

    Gajjala, R; Mamidipudi, A

    1999-07-01

    This article reports on the implications and benefits of Internet technology among women from developing countries. Cyberfeminism is the practice of feminism in cyberspace. Feminists believe that women should take control and augment Internet technologies to empower themselves. Learning to use the computers, getting "connected," and surfing the Internet are encouraged among all women with the aim of advancing feminist causes and empowering women. The Internet has been observed to cause radical changes in the way business and social activities are conducted. A description of how two women have engaged in cyberfeminism and worked in development and technology programs is included. One contributor, Annapurna Mamipudi, is involved in a non-governmental organization working with traditional handloom weavers in India Another contributor is Radhika Gajjala, who works in academia and creates on-line "discussion lists" and Web sites from her North American geographical location. Her job is to create spaces that provide opportunities for dialogue and collaboration among women with Internet access all over the world.

  6. Society 3.0: How Technology Is Reshaping Education, Work and Society

    ERIC Educational Resources Information Center

    Wilen-Daugenti, Tracey

    2012-01-01

    Higher education in the U.S. has traditionally prepared students for work and social success, but with families, work, and society itself undergoing revolutionary change, is this preparation sufficient to develop the 21st-century workforce? This book explores how evolving family structures, new ways of balancing work and personal lives, and rapid…

  7. (abstract) ARGOS: a System to Monitor Ulysses Nutation and Thruster Firings from Variations of the Spacecraft Radio Signal

    NASA Technical Reports Server (NTRS)

    McElrath, T. P.; Cangahuala, L. A.; Miller, K. J.; Stravert, L. R.; Garcia-Perez, Raul

    1995-01-01

    Ulysses is a spin-stabilized spacecraft that experienced significant nutation after its launch in October 1990. This was due to the Sun-spacecraft-Earth geometry, and a study of the phenomenon predicted that the nutation would again be a problem during 1994-95. The difficulty of obtaining nutation estimates in real time from the spacecraft telemetry forced the ESA/NASA Ulysses Team to explore alternative information sources. The work performed by the ESA Operations Team provided a model for a system that uses the radio signal strength measurements to monitor the spacecraft dynamics. These measurements (referred to as AGC) are provided once per second by the tracking stations of the DSN. The system was named ARGOS (Attitude Reckoning from Ground Observable Signals) after the ever-vigilant, hundred-eyed giant of Greek Mythology. The ARGOS design also included Doppler processing, because Doppler shifts indicate thruster firings commanded by the active nutation control carried out onboard the spacecraft. While there is some visibility into thruster activity from telemetry, careful processing of the high-sample-rate Doppler data provides an accurate means of detecting the presence and time of thruster firings. DSN Doppler measurements are available at a ten-per-second rate in the same tracking data block as the AGC data.

  8. Software Technology Transfer and Export Control.

    DTIC Science & Technology

    1981-01-01

    development projects of their own. By analogy, a Soviet team might be able to repeat the learning experience of the ADEPT-50 junior staff...recommendations concerning product form and further study . The posture of this group has been to consider software technology and its transfer as a process...and views of the Software Subgroup of Technical Working Group 7 (Computers) of the Critical Technologies Project . The work reported

  9. Has Technology Been Considered? A Guide for IEP Teams. CASE/TAM Assistive Technology Policy and Practice Series.

    ERIC Educational Resources Information Center

    Chambers, A. C.

    This guide compiles information essential to a working knowledge of assistive technology for children with disabilities. It addresses the definition of assistive technology and provides information on laws which direct the provision of assistive technology. The manual provides a framework to guide the Individualized Education Program (IEP) team as…

  10. Jen Gustetic visits Swamp Works

    NASA Image and Video Library

    2016-10-28

    Jenn Gustetic, NASA's Small Business Innovation Research Program executive, talks with Rob Mueller, senior technologist and co-founder of Kennedy Space Center's Swamp Works. Gustetic met team members and viewed many of the pioneering technologies and innovations in development at Kennedy. Swamp Works is a hands-on, lean development environment for innovation following the philosophies pioneered in Kelly Johnson's Skunk Works and Werner von Braun's development shops. The Swamp Works establishes rapid, innovative and cost-effective exploration mission solutions through a highly collaborative, "no walls" approach, leveraging partnerships across NASA, industry and academia.

  11. Success in large high-technology projects: What really works?

    NASA Astrophysics Data System (ADS)

    Crosby, P.

    2014-08-01

    Despite a plethora of tools, technologies and management systems, successful execution of big science and engineering projects remains problematic. The sheer scale of globally funded projects such as the Large Hadron Collider and the Square Kilometre Array telescope means that lack of project success can impact both on national budgets, and collaborative reputations. In this paper, I explore data from contemporary literature alongside field research from several current high-technology projects in Europe and Australia, and reveal common `pressure points' that are shown to be key influencers of project control and success. I discuss the how mega-science projects sit between being merely complicated, and chaotic, and explain the importance of understanding multiple dimensions of project complexity. Project manager/leader traits are briefly discussed, including capability to govern and control such enterprises. Project structures are examined, including the challenge of collaborations. I show that early attention to building project resilience, curbing optimism, and risk alertness can help prepare large high-tech projects against threats, and why project managers need to understand aspects of `the silent power of time'. Mission assurance is advanced as a critical success function, alongside the deployment of task forces and new combinations of contingency plans. I argue for increased project control through industrial-style project reviews, and show how post-project reviews are an under-used, yet invaluable avenue of personal and organisational improvement. Lastly, I discuss the avoidance of project amnesia through effective capture of project knowledge, and transfer of lessons-learned to subsequent programs and projects.

  12. Cutting Edge Technologies Presentation: An Overview of Developing Sensor Technology Directions and Possible Barriers to New Technology Implementation

    NASA Technical Reports Server (NTRS)

    Hunter, Gary W.

    2007-01-01

    The aerospace industry requires the development of a range of chemical sensor technologies for such applications as leak detection, emission monitoring, fuel leak detection, environmental monitoring, and fire detection. A range of chemical sensors are being developed based on micromachining and microfabrication technology to fabricate microsensors with minimal size, weight, and power consumption; and the use of nanomaterials and structures to develop sensors with improved stability combined with higher sensitivity, However, individual sensors are limited in the amount of information that they can provide in environments that contain multiple chemical species. Thus, sensor arrays are being developed to address detection needs in such multi-species environments. These technologies and technical approaches have direct relevance to breath monitoring for clinical applications. This presentation gives an overview of developing cutting-edge sensor technology and possible barriers to new technology implementation. This includes lessons learned from previous microsensor development, recent work in development of a breath monitoring system, and future directions in the implementation of cutting edge sensor technology.

  13. Research and Technology 1997

    NASA Technical Reports Server (NTRS)

    1998-01-01

    This report highlights the challenging work accomplished during fiscal year 1997 by Ames research scientists and engineers. The work is divided into accomplishments that support the goals of NASA s four Strategic Enterprises: Aeronautics and Space Transportation Technology, Space Science, Human Exploration and Development of Space (HEDS), and Earth Science. NASA Ames Research Center s research effort in the Space, Earth, and HEDS Enterprises is focused i n large part to support Ames lead role for Astrobiology, which broadly defined is the scientific study of the origin, distribution, and future of life in the universe. This NASA initiative in Astrobiology is a broad science effort embracing basic research, technology development, and flight missions. Ames contributions to the Space Science Enterprise are focused in the areas of exobiology, planetary systems, astrophysics, and space technology. Ames supports the Earth Science Enterprise by conducting research and by developing technology with the objective of expanding our knowledge of the Earth s atmosphere and ecosystems. Finallv, Ames supports the HEDS Enterprise by conducting research, managing spaceflight projects, and developing technologies. A key objective is to understand the phenomena surrounding the effects of gravity on living things. Ames has also heen designated the Agency s Center of Evcellence for Information Technnlogv. The three cornerstones of Information Technology research at Ames are automated reasoning, human-centered computing, and high performance computing and networking.

  14. Prospective Evaluation of Changes in Tumor Size and Tumor Metabolism in Patients with Advanced Gastric Cancer Undergoing Chemotherapy: Association and Clinical Implication.

    PubMed

    Park, Seongyeol; Ha, Seunggyun; Kwon, Hyun Woo; Kim, Woo Hyoung; Kim, Tae-Yong; Oh, Do-Youn; Cheon, Gi Jeong; Bang, Yung-Jue

    2017-06-01

    A change in tumor size is a well-validated and commonly used value for evaluating response to chemotherapy in cancer. Metabolic changes induced by chemotherapy are related to prognosis in several tumor types. However, the clinical implication of metabolic changes in patients with advanced gastric cancer (AGC) undergoing chemotherapy remains unclear. We aimed to evaluate response of tumor size and metabolism in AGC during chemotherapy and to reveal the relationship between them in view of their impact on patient survival. Methods: We prospectively enrolled patients with AGC before the initiation of first-line palliative chemotherapy. Using baseline and follow-up contrast-enhanced CT and 18 F-FDG PET, we assessed the tumor diameter, SUV max , and total lesion glycolysis in each lesion and their changes during chemotherapy at the same time. We included all lesions with the maximal longest diameters over 1 cm on CT, and each lesion was evaluated by matched 18 F-FDG PET. We analyzed the association between changes in tumor metabolism and tumor size and performed outcome analysis on overall survival (OS) and progression-free survival (PFS). Results: Seventy-four patients were enrolled, and the number of all lesions included in this study was 620. Compared with adenocarcinomas, poorly cohesive carcinomas demonstrated lower SUV max irrespective of tumor size ( P < 0.001). Human epidermal growth factor receptor 2 (HER2)-positive tumors showed higher SUV max than HER2-negative tumors ( P = 0.002). The changes in SUV max due to chemotherapy had a linear correlation with the changes in tumor size of each lesion, and a 30% tumor size reduction was associated with a 50% SUV max reduction ( P < 0.001). Total lesion glycolysis changes also correlated with tumor size changes ( P < 0.001). Better OS and PFS were obtained in patients with both tumor size and SUV max reduction than in patients with either size or SUV max reduction only (OS, P = 0.003; PFS, P = 0.038). Conclusion

  15. Space Technology Plasma Issues in 2001

    NASA Technical Reports Server (NTRS)

    Garrett, Henry (Editor); Feynman, Joan (Editor); Gabriel, Stephen (Editor)

    1986-01-01

    The purpose of the workshop was to identify and discuss plasma issues that need to be resolved during the next 10 to 20 years (circa 2001) to facilitate the development of the advanced space technology that will be required 20 or 30 years into the future. The workshop consisted of 2 days of invited papers and 2 sessions of contributed poster papers. During the third day the meeting broke into 5 working groups, each of which held discussions and then reported back to the conference as a whole. The five panels were: Measurements Technology and Active Experiments Working Group; Advanced High-Voltage, High-Power and Energy-Storage Space Systems Working Group; Large Structures and Tethers Working Group; Plasma Interactions and Surface/Materials Effects Working Group; and Beam Plasmas, Electronic Propulsion and Active Experiments Using Beams Working Group.

  16. First-line chemotherapy with S-1 alone or S-1 plus cisplatin for elderly patients with advanced gastric cancer: a multicenter propensity score matched study.

    PubMed

    Makiyama, Akitaka; Kunieda, Kenji; Noguchi, Masaaki; Kajiwara, Takeshi; Tamura, Takao; Takeda, Koji; Sugiyama, Junko; Minashi, Keiko; Moriwaki, Toshikazu; Sugimoto, Naotoshi; Nagase, Michitaka; Negoro, Yuji; Tsuda, Takashi; Shimodaira, Hideki; Okano, Naohiro; Tsuji, Akihito; Sakai, Daisuke; Yanagihara, Kazuhiro; Ueda, Shinya; Tamura, Shingo; Otsu, Satoshi; Honda, Takuya; Matsushita, Yuzo; Okuno, Tatsuya; Kashiwada, Tomomi; Nozaki, Akira; Ebi, Masahide; Okuda, Hiroyuki; Shimokawa, Mototsugu; Hironaka, Shuichi; Hyodo, Ichinosuke; Baba, Eishi; Boku, Narikazu; Muro, Kei; Esaki, Taito

    2018-01-20

    Fluoropyrimidine and platinum combination is the standard treatment for advanced or recurrent gastric cancer (AGC). However, fluoropyrimidine monotherapy is commonly used for elderly patients with AGC because of its good tolerability. In this multicenter retrospective study, we collected clinical data of AGC patients aged 70 years or older, treated with S-1 alone or S-1 plus cisplatin (SP) as the first-line treatment between January 2009 and December 2011. Propensity score matched cohorts (PSMC) were used for reducing the confounding effects to compare efficacy and safety between the two treatment groups. Cox regression analysis was performed to clarify the prognostic factors. PSMC (n = 109 in each group) were selected from among 444 eligible patients (S-1 group, 210; SP group, 234); the S-1 group included more patients deemed unfit for intensive chemotherapy than the SP group (e.g., higher age, poorer PS, poor renal function). In the PSMC, patients' characteristics were comparable between groups, except the male ratio (S-1 group, 64.2%; SP group, 77.1%; p = 0.04). No significant differences were observed in either overall survival [hazard ratio (HR) 0.93, p = 0.63] or progression-free survival (HR 1.09, p = 0.61). Severe adverse events (AEs) and hospitalization due to AEs were more frequent in the SP group than in the S-1 group (p < 0.001 each). Our findings do not support the survival benefit of SP over S-1 in elderly patients with AGC. We are now conducting a prospective comparative study to optimize treatment strategy and explore applicability of the geriatric assessment for these patients.

  17. Overexpression of Plasminogen Activator Inhibitor-1 in Advanced Gastric Cancer with Aggressive Lymph Node Metastasis

    PubMed Central

    Suh, Yun-Suhk; Yu, Jieun; Kim, Byung Chul; Choi, Boram; Han, Tae-Su; Ahn, Hye Seong; Kong, Seong-Ho; Lee, Hyuk-Joon; Kim, Woo Ho; Yang, Han-Kwang

    2015-01-01

    Purpose The purpose of this study is to investigate differentially expressed genes using DNA microarray between advanced gastric cancer (AGC) with aggressive lymph node (LN) metastasis and that with a more advanced tumor stage but without LN metastasis. Materials and Methods Five sample pairs of gastric cancer tissue and normal gastric mucosa were taken from three patients with T3N3 stage (highN) and two with T4N0 stage (lowN). Data from triplicate DNA microarray experiments were analyzed, and candidate genes were identified using a volcano plot that showed ≥ 2-fold differential expression and were significant by Welch's t test (p < 0.05) between highN and lowN. Those selected genes were validated independently by reverse-transcriptase–polymerase chain reaction (RT-PCR) using five AGC patients, and tissue-microarray (TMA) comprising 47 AGC patients. Results CFTR, LAMC2, SERPINE2, F2R, MMP7, FN1, TIMP1, plasminogen activator inhibitor-1 (PAI-1), ITGB8, SDS, and TMPRSS4 were commonly up-regulated over 2-fold in highN. REG3A, CD24, ITLN1, and WBP5 were commonly down-regulated over 2-fold in lowN. Among these genes, overexpression of PAI-1 was validated by RT-PCR, and TMA showed 16.7% (7/42) PAI-1 expression in T3N3, but none (0/5) in T4N0 (p=0.393). Conclusion DNA microarray analysis and validation by RT-PCR and TMA showed that overexpression of PAI-1 is related to aggressive LN metastasis in AGC. PMID:25687870

  18. Laparoscopic subtotal gastrectomy for advanced gastric cancer: technical aspects and surgical, nutritional and oncological outcomes.

    PubMed

    Nakauchi, Masaya; Suda, Koichi; Nakamura, Kenichi; Shibasaki, Susumu; Kikuchi, Kenji; Nakamura, Tetsuya; Kadoya, Shinichi; Ishida, Yoshinori; Inaba, Kazuki; Taniguchi, Keizo; Uyama, Ichiro

    2017-11-01

    Higher morbidity in total gastrectomy than in distal gastrectomy has been reported, but laparoscopic subtotal gastrectomy (LsTG) has been reported to be safe and feasible in early gastric cancer (GC). We determined the surgical, nutritional and oncological outcomes of LsTG for advanced gastric cancer (AGC). Of the 816 consecutive patients with GC who underwent radical gastrectomy at our institution between 2008 and 2012, 253 who underwent curative laparoscopic gastrectomy (LG) for AGC were enrolled. LsTG was indicated for patients with upper stomach third tumors, who hoped to avoid total gastrectomy, <4 cm to the esophagogastric junction and a 2-cm proximal margin with cut end negative in frozen section, whereas laparoscopic conventional distal gastrectomy (LcDG) and laparoscopic total gastrectomy (LTG) were performed otherwise. Surgical outcomes and postoperative nutritional status were primarily assessed. Of 253 patients, the morbidity (Clavien-Dindo classification grade ≥ III) was 17.0% (43 patients). The 3-year overall survival and 3-year recurrence-free survival rates were 80.2 and 73.5%, respectively. LcDG, LsTG and LTG were performed in 121, 27 and 105 patients, individually. Morbidity was strongly associated with LTG (P = 0.001). Postoperative loss of body weight was significantly greater after LTG in comparison with LcDG or LsTG (P < 0.001). No difference in morbidity and postoperative loss of body weight were observed between LcDG and LsTG group. LG for AGC was feasible and safe surgically and oncologically. LsTG for AGC may be safer than LTG from surgical and postoperative nutritional point of view.

  19. Energy technology evaluation report: Energy security

    NASA Astrophysics Data System (ADS)

    Koopman, R.; Lamont, A.; Schock, R.

    1992-09-01

    Energy security was identified in the National Energy Strategy (NES) as a major issue for the Department of Energy (DOE). As part of a process designed by the DOE to identify technologies important to implementing the NES, an expert working group was convened to consider which technologies can best contribute to reducing the nation's economic vulnerability to future disruptions of world oil supplies, the working definition of energy security. Other working groups were established to deal with economic growth, environmental quality, and technical foundations. Energy Security working group members were chosen to represent as broad a spectrum of energy supply and end-use technologies as possible and were selected for their established reputations as experienced experts with an ability to be objective. The time available for this evaluation was very short. The group evaluated technologies using criteria taken from the NES which can be summarized for energy security as follows: diversifying sources of world oil supply so as to decrease the increasing monopoly status of the Persian Gulf region; reducing the importance of oil use in the US economy to diminish the impact of future disruptions in oil supply; and increasing the preparedness of the US to deal with oil supply disruptions by having alternatives available at a known price. The result of the first phase of the evaluation process was the identification of technology groups determined to be clearly important for reducing US vulnerability to oil supply disruptions. The important technologies were mostly within the high leverage areas of oil and gas supply and transportation demand but also included hydrogen utilization, biomass, diversion resistant nuclear power, and substitute industrial feedstocks.

  20. A mixed pseudospectral/finite difference method for a thermally driven fluid in a nonuniform gravitational field

    NASA Technical Reports Server (NTRS)

    Macaraeg, M. G.

    1985-01-01

    A numerical study of the steady, axisymmetric flow in a heated, rotating spherical shell is conducted to model the Atmospheric General Circulation Experiment (AGCE) proposed to run aboard a later Shuttle mission. The AGCE will consist of concentric rotating spheres confining a dielectric fluid. By imposing a dielectric field across the fluid a radial body force will be created. The numerical solution technique is based on the incompressible Navier-Stokes equations. In the method a pseudospectral technique is used in the latitudinal direction, and a second-order accurate finite difference scheme discretizes time and radial derivatives. This paper discusses the development and performance of this numerical scheme for the AGCE which has been modeled in the past only by pure FD formulations. In addition, previous models have not investigated the effect of using a dielectric force to simulate terrestrial gravity. The effect of this dielectric force on the flow field is investigated as well as a parameter study of varying rotation rates and boundary temperatures. Among the effects noted are the production of larger velocities and enhanced reversals of radial temperature gradients for a body force generated by the electric field.

  1. [Influence of vaginal microflora on the presence of persistent atypical squamous cells and atypical glandular cells in pap smear--a 3-year study].

    PubMed

    Ludwin, Inga; Ludwin, Artur; Basta, Antoni

    2010-05-01

    the evaluation of influence of abnormal vaginal biocoenosis on presence and maintenance ASC and AGC in Pap smears. The study group consisted of 242 non-pregnant women (25-65 years of age): 207 women (4.96%) with atypical sqamous cells and 35 (0.7%) with atypical glandular cells. In all women the vaginal flora was assessed by Nugent scale. Vaginal flora was normal in 157 (75.8%) and pathological in 50 (24.1%) women with ASC. In the ASC subgroup, the highest proportion of physiological vaginal flora was observed in 151 patients (77.4%) with ASC-US, in comparison to 44 (22.6%) with ASC-H, in which the percentage of women with normal or abnormal flora was the same (50% vs 50%). This difference was statistically significant. In case of AGC, vaginal culture was physiological in 23 (65.7%) women, and in 12 (34.3%) abnormal vaginal flora with features of the inflammation. The statistically significant influence of abnormal vaginal flora on the presence of atypical endometrial and endocervical cells was not observed. We did not observed any influence of abnormal vaginal flora on the presence, regression and progression of ASC and AGC.

  2. Working Mothers and Their Children

    ERIC Educational Resources Information Center

    Mead, Margaret

    1970-01-01

    How our technology and social structure adversely affect stability and continuity of care for infants whose mothers work outside the home. Various solutions to the resulting problems are suggested. (RH)

  3. Good relations with technology: Empirical ethics and aesthetics in care.

    PubMed

    Pols, Jeannette

    2017-01-01

    This article is a written version of the lecture for the IPONS conference in Stockholm. The article starts from the claim that there is no such thing as technology, only different variations of technologies. These technologies, plural, all have their specific workings that we can only learn about by studying these empirically, by analysing the relations between people and their technologies. These relations are always unpredictable, as it is not given beforehand what values the participants pursue. Studying and understanding the workings of healthcare technology is a crucial task for nursing studies, as nurses are often key actors in making these devices work. The article hands the reader some tools to engage in the study of technologies in practice, using an empirical ethics approach. © 2016 John Wiley & Sons Ltd.

  4. Technological Innovation and Strategic Human Resource Management: Developing a Theory.

    ERIC Educational Resources Information Center

    Gattiker, Urs E.

    Technological innovation affects the structure and content of jobs. Research indicates that there is a need for a theory of technological innovation and strategic human resource management considering several factors, such as an employee's beliefs about the effect of technological innovations on the quality of work life and work content.…

  5. OAST space technology accomplishments FY 1991

    NASA Technical Reports Server (NTRS)

    1992-01-01

    The program consists of a continuum of space research and technology activities ranging from initial research to the full scale test of prototype equipment in space. Activities include work that is performed by in-house staff at the NASA Centers, university researchers supported by NASA funded grants and contracts, and industrial aerospace organizations under contract to NASA. These diverse activities provide advances in technology breakthroughs that may revolutionalize a technical discipline or mission concept. The work is managed and coordinated by OAST through a process that integrates the best available talent and capability in NASA, industry, and universities into a National civil space research and technology program.

  6. Evaluation of Policy and Research Interventions in Science and Technology: Consequence Assessment of Regulatory and Technology Transfer Programs

    ERIC Educational Resources Information Center

    Dias, Mary Beatrice

    2011-01-01

    This research contributes to efforts in assessment studies related to science and technology interventions. The work presented in this thesis focuses on understanding the effects of policies that influence science and technology interventions, and determining the impact of science and technology interventions themselves. Chapter 1 explores how…

  7. Research and Technology, 1994

    NASA Technical Reports Server (NTRS)

    1995-01-01

    This report selectively summarizes the NASA Lewis Research Center's research and technology accomplishments for the fiscal year 1994. It comprises approximately 200 short articles submitted by the staff members of the technical directorates. The report is organized into six major sections: Aeronautics, Aerospace Technology, Space Flight Systems, Engineering and Computational Support, Lewis Research Academy, and Technology Transfer. A table of contents and author index have been developed to assist the reader in finding articles of special interest. This report is not intended to be a comprehensive summary of all research and technology work done over the past fiscal year. Most of the work is reported in Lewis-published technical reports, journal articles, and presentations prepared by Lewis staff members and contractors. In addition, university grants have enabled faculty members and graduate students to engage in sponsored research that is reported at technical meetings or in journal articles. For each article in this report a Lewis contact person has been identified, and where possible, reference documents are listed so that additional information can be easily obtained. The diversity of topics attests to the breadth of research and technology being pursued and to the skill mix of the staff that makes it possible.

  8. Novel Therapeutic Strategy for the Prevention of Bone Fractures

    DTIC Science & Technology

    2014-08-01

    GAC CTT CAA CAC CCC GTG GCC ATC TCC TGC TCG AAG TC Meredith et al 2011* Mstn ACT GGA CCT CTC GAT AGA ACA CTC ACT TAG TGC TGT GTG TGT GGA GAT...NM_010834.2 IGF-1 CAG ACA GGA GCC CAG GAA AG AAG TGC CGT ATC CCA GAG GA NM_184052 MHC ACA GTC AGA GGT GTG ACTC AGC CG CCG ACT TGC GGA GGA AAG GTG C...AGC AGA GA TGA GTG CCT GCG GTA CAG AT NM_007553.2 RUNX-2 GGA AAG GCA CTG ACT GAC CTA ACA AAT TCT AAG CTT GGG AGG A NM_009820 Osx ACT ACC CAC CCT TCC

  9. New Technologies and Training in Metalworking.

    ERIC Educational Resources Information Center

    Belitsky, A. Harvey

    This report reviews the role of technological factors in metalworking and the training required to adapt to new metalworking technologies. Focus is on whether firms that have adopted the new technologies have encountered obstacles in training and developing the skills of their work forces. The report is organized in three parts. Parts I and II…

  10. Information Technology and Disabilities, 1995.

    ERIC Educational Resources Information Center

    McNulty, Tom, Ed.

    1995-01-01

    Four issues of this newsletter on information technology and disabilities (ITD) contain the following articles: "Developing an Accessible Online Public Access Catalog at the Washington Talking Book and Braille Library" (Charles Hamilton); "Assistive Technology in the Science Laboratory: A Talking Laboratory Work Station for Visually Impaired…

  11. Effects of new ways of working on work hours and work location, health and job-related outcomes.

    PubMed

    Nijp, Hylco H; Beckers, Debby G J; van de Voorde, Karina; Geurts, Sabine A E; Kompier, Michiel A J

    2016-01-01

    New ways of working (NWW) is a type of work organization that is characterized by temporal and spatial flexibility, often combined with extensive use of information and communication technologies (ICT) and performance-based management. In a three-wave intervention study, we examined the effects of NWW on both the organization of work (changes in control over time and place of work; working hours and work location; and other key job characteristics), and on employees' outcomes (work-nonwork balance; health and well-being; and job-related outcomes). We applied a quasi-experimental design within a large Dutch financial company (N = 2,912). We studied an intervention group (n = 2,391) and made comparisons with a reference group (n = 521). There were three study waves: (i) one/two months before, and (ii) 4 months and (iii) 10 months after implementation of NWW. Repeated measures analyses of covariance (involving 361 participants from the intervention group and 80 participants from the reference group) showed a large and significant shift from hours worked at the office to hours worked at home after implementation of NWW. Accordingly, commuting time was reduced. Employees remained working on week days and during day time. Psychosocial work-characteristics, work-nonwork balance, stress, fatigue, and job-related outcomes remained favourable and largely unaffected, but the health score in the intervention group decreased (medium effect). These findings suggest that the implementation of NWW does not necessarily lead to changes in psychosocial work characteristics, well-being or job-related outcomes.

  12. Embracing Complexity: Using Technology to Develop a Life-Long Learning Model for Non-Working Time in the Interdependent Homes for Adults with Autism Spectrum Disorders

    ERIC Educational Resources Information Center

    Chiang, I-Tsun; Chen, Mei-Li

    2011-01-01

    The purpose of this study was to employ complexity theory as a theoretical framework and technology to facilitate the development of a life-long learning model for non-working time in the interdependent homes for adults with Autism Spectrum Disorders (ASD). A "Shining Star Sustainable Action Project" of the ROC Foundation for Autistic…

  13. The Educational Technology of Ethical Development for Students

    ERIC Educational Resources Information Center

    Song, Ting; Ustin, Pavel N.; Popov, Leonid M.; Mudarisov, Marat M.

    2017-01-01

    The relevance of this work was connected with the problem of ethical competencies forming among future psychologists during their learning in university. The first task of research was to work out the technology of ethical development for students-psychologists. The structure of this technology included four main educational components:…

  14. Internet and video technology in psychotherapy supervision and training.

    PubMed

    Wolf, Abraham W

    2011-06-01

    The seven articles in this special section on the use of Internet and video technology represent the latest growth on one branch of the increasingly prolific and differentiated work in the technology of psychotherapy. In addition to the work presented here on video and the Internet applications to supervision and training, information technology is changing the field of psychotherapy through computer assisted therapies and virtual reality interventions.

  15. New Ways of Working: does flexibility in time and location of work change work behavior and affect business outcomes?

    PubMed

    Blok, Merle M; Groenesteijn, Liesbeth; Schelvis, Roos; Vink, Peter

    2012-01-01

    In the changing modern economy some new factors have been addressed that are of importance for productivity and economic growth, such as human skills, workplace organization, information and communication technologies (ICT) and knowledge sharing. An increasing number of companies and organizations are implementing measures to better address these factors, often referred to as 'the New Ways of Working (NWW)'. This consists of a large variety of measures that enable flexibility in the time and location of work. Expectations of these measures are often high, such as a reduction in operating costs and an increase of productivity. However, scientific proof is still lacking, and it is worth asking whether al these implementations actually cause a change in work behavior and effect business outcomes positively. This article describes a case study of three departments (total of 73 employees) that changed from a traditional way of working towards a new way of working. Questionnaires and a new developed objective measurement system called 'work@task' were used to measure changes in work behavior (i.e. increased variation in work location, work times and a change towards NWW management style) and the effect on business objectives such as knowledge sharing, employees satisfaction, and collaboration.

  16. New ways of working: does flexibility in time and location of work change work behavior and affect business outcomes?

    PubMed

    Blok, Merle M; Groenesteijn, Liesbeth; Schelvis, Roos; Vink, Peter

    2012-01-01

    In the changing modern economy some new factors have been addressed that are of importance for productivity and economic growth, such as human skills, workplace organization, information and communication technologies (ICT) and knowledge sharing. An increasing number of companies and organizations are implementing measures to better address these factors, often referred to as 'the New Ways of Working (NWW)'. This consists of a large variety of measures that enable flexibility in the time and location of work. Expectations of these measures are often high, such as a reduction in operating costs and an increase of productivity. However, scientific proof is still lacking, and it is worth asking whether al these implementations actually cause a change in work behavior and effect business outcomes positively. This article describes a case study of three departments (total of 73 employees) that changed from a traditional way of working towards a new way of working. Questionnaires and a new developed objective measurement system called 'work@task' were used to measure changes in work behavior (i.e. increased variation in work location, work times and a change towards NWW management style) and the effect on business objectives such as knowledge sharing, employees satisfaction, and collaboration.

  17. Technology and Environmental Education: An Integrated Curriculum

    ERIC Educational Resources Information Center

    Willis, Jana M.; Weiser, Brenda

    2005-01-01

    Preparing teacher candidates to integrate technology into their future classrooms effectively requires experience in instructional planning that utilizes technology to enhance student learning. Teacher candidates need to work with curriculum that supports a variety of technologies. Using Project Learning Tree and environmental education (EE),…

  18. Using Digital Technologies in Clinical HIV Research: Real-World Applications and Considerations for Future Work

    PubMed Central

    Bull, Sheana; Dietrich, Janan; Haberer, Jessica E; Van Der Pol, Barbara; Voronin, Yegor; Wall, Kristin M; Whalen, Christopher; Priddy, Frances

    2017-01-01

    Background Digital technologies, especially if used in novel ways, provide a number of potential advantages to clinical research in trials related to human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) and may greatly facilitate operations as well as data collection and analysis. These technologies may even allow answering questions that are not answerable with older technologies. However, they come with a variety of potential concerns for both the participants and the trial sponsors. The exact challenges and means for alleviation depend on the technology and on the population in which it is deployed, and the rapidly changing landscape of digital technologies presents a challenge for creating future-proof guidelines for technology application. Objective The aim of this study was to identify and summarize some common themes that are frequently encountered by researchers in this context and highlight those that should be carefully considered before making a decision to include these technologies in their research. Methods In April 2016, the Global HIV Vaccine Enterprise surveyed the field for research groups with recent experience in novel applications of digital technologies in HIV clinical research and convened these groups for a 1-day meeting. Real-world uses of various technologies were presented and discussed by 46 attendees, most of whom were researchers involved in the design and conduct of clinical trials of biomedical HIV prevention and treatment approaches. After the meeting, a small group of organizers reviewed the presentations and feedback obtained during the meeting and categorized various lessons-learned to identify common themes. A group of 9 experts developed a draft summary of the findings that was circulated via email to all 46 attendees for review. Taking into account the feedback received, the group finalized the considerations that are presented here. Results Meeting presenters and attendees discussed the many

  19. Societal Incentives for Work: Lessons from Tanzania.

    ERIC Educational Resources Information Center

    Bjorkquist, David C.

    1993-01-01

    A study of work and economics, technology, and culture in Tanzania reveals that (1) material returns to rural workers were barely life sustaining; (2) people live dignified lives without consuming much; (3) simpler technological solutions were better; (4) tension exists between competitiveness and humaneness; and (5) tribal traditions contribute…

  20. Transferability of economic evaluations of medical technologies: a new technology for orthopedic surgery.

    PubMed

    Steuten, Lotte; Vallejo-Torres, Laura; Young, Terry; Buxton, Martin

    2008-05-01

    Transferring results of economic evaluations across countries or jurisdictions can potentially save scarce evaluation resources while helping to make market access and reimbursement decisions in a timely fashion. This article points out why transferring results of economic evaluations is particularly important in the field of medical technologies. It then provides an overview of factors that are previously identified in the literature as affecting transferability of economic evaluations, as well as methods for transferring results in a scientifically sound way. As the current literature almost exclusively relates to transferability of pharmacoeconomic evaluations, this article highlights those factors and methodologies that are of particular relevance to transferring medical technology assessments. Considering the state-of-the-art literature and a worked, real life, example of transferring an economic evaluation of a product used in orthopedic surgery, we provide recommendations for future work in this important area of medical technology assessment.