42 CFR 93.410 - Final HHS action with no settlement or finding of research misconduct.

Code of Federal Regulations, 2012 CFR

2012-10-01

... research misconduct. 93.410 Section 93.410 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND... FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.410 Final HHS action with no settlement or...

42 CFR 93.410 - Final HHS action with no settlement or finding of research misconduct.

Code of Federal Regulations, 2010 CFR

2010-10-01

... research misconduct. 93.410 Section 93.410 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND... FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.410 Final HHS action with no settlement or...

42 CFR 93.410 - Final HHS action with no settlement or finding of research misconduct.

Code of Federal Regulations, 2011 CFR

2011-10-01

... research misconduct. 93.410 Section 93.410 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND... FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.410 Final HHS action with no settlement or...

42 CFR 93.410 - Final HHS action with no settlement or finding of research misconduct.

Code of Federal Regulations, 2013 CFR

2013-10-01

... research misconduct. 93.410 Section 93.410 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND... FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.410 Final HHS action with no settlement or...

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

42 CFR 93.405 - Notifying the respondent of findings of research misconduct and HHS administrative actions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... misconduct and HHS administrative actions. 93.405 Section 93.405 Public Health PUBLIC HEALTH SERVICE... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Responsibilities of the U.S. Department of Health and Human Services Research Misconduct Issues § 93.405 Notifying the respondent of...

The HHS Mandate and Religious Liberty: A Primer

ERIC Educational Resources Information Center

Keim, Adele Auxier

2013-01-01

"We are in a war," Health and Human Services Secretary Kathleen Sebelius declared to cheers at a 2011 National Abortion and Reproductive Rights Action League (NARAL) Pro-Choice America fund-raiser. Secretary Sebelius was referring in part to the uproar caused by the "HHS Mandate," her agency's rule that employer-provided…

HHS Archive Home Page

Science.gov Websites

Health and Human Service staff. HHS Blog Exit Disclaimer This collection includes HHS blog posts Safety Working Group* Indian Health Service (IHS) Indian Health Service* National Institutes of Health )* HealthIT.gov (ONC)* Office of Minority Health (ASH)* Public Health Emergency (ASPR)* Stopbullying.gov (ASPA

42 CFR 93.200 - Administrative action.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Administrative action. 93.200 Section 93.200 Public... MISCONDUCT Definitions § 93.200 Administrative action. Administrative action means— (a) An HHS action in... related to that research or research training and to conserve public funds; or (b) An HHS action in...

24 CFR 232.620 - Determination of compliance by HHS.

Code of Federal Regulations, 2012 CFR

2012-04-01

... of Fire Safety Equipment Special Requirements § 232.620 Determination of compliance by HHS. An... the fire safety equipment has been installed, will be in compliance with the HHS requirements for fire... services along with a plan prepared by the applicant for correcting those deficiencies. In such event, HHS...

24 CFR 232.620 - Determination of compliance by HHS.

Code of Federal Regulations, 2014 CFR

2014-04-01

... of Fire Safety Equipment Special Requirements § 232.620 Determination of compliance by HHS. An... the fire safety equipment has been installed, will be in compliance with the HHS requirements for fire... services along with a plan prepared by the applicant for correcting those deficiencies. In such event, HHS...

45 CFR 74.12 - Forms for applying for HHS financial assistance.

Code of Federal Regulations, 2011 CFR

2011-10-01

... from the HHS awarding agency or the Catalog of Federal Domestic Assistance. The SPOC shall advise the... for applying for HHS financial assistance. (a) HHS awarding agencies shall comply with the applicable..., HHS awarding agencies should use the SF-424 series and its program narrative whenever possible. (b...

45 CFR 74.12 - Forms for applying for HHS financial assistance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... from the HHS awarding agency or the Catalog of Federal Domestic Assistance. The SPOC shall advise the... for applying for HHS financial assistance. (a) HHS awarding agencies shall comply with the applicable..., HHS awarding agencies should use the SF-424 series and its program narrative whenever possible. (b...

45 CFR 74.12 - Forms for applying for HHS financial assistance.

Code of Federal Regulations, 2012 CFR

2012-10-01

... from the HHS awarding agency or the Catalog of Federal Domestic Assistance. The SPOC shall advise the... for applying for HHS financial assistance. (a) HHS awarding agencies shall comply with the applicable..., HHS awarding agencies should use the SF-424 series and its program narrative whenever possible. (b...

45 CFR 74.12 - Forms for applying for HHS financial assistance.

Code of Federal Regulations, 2013 CFR

2013-10-01

... from the HHS awarding agency or the Catalog of Federal Domestic Assistance. The SPOC shall advise the... for applying for HHS financial assistance. (a) HHS awarding agencies shall comply with the applicable..., HHS awarding agencies should use the SF-424 series and its program narrative whenever possible. (b...

45 CFR 74.12 - Forms for applying for HHS financial assistance.

Code of Federal Regulations, 2014 CFR

2014-10-01

... from the HHS awarding agency or the Catalog of Federal Domestic Assistance. The SPOC shall advise the... for applying for HHS financial assistance. (a) HHS awarding agencies shall comply with the applicable..., HHS awarding agencies should use the SF-424 series and its program narrative whenever possible. (b...

Patricia Hartge Receives the HHS Career Achievement Award

Cancer.gov

In February 2012, Patricia Hartge, Sc.D., Deputy Director of DCEG’s Epidemiology and Biostatistics Program, received the Department of Health and Human Services (HHS) Career Achievement Award at the HHS Honor Awards Ceremony.

Resilience or hope? Incremental and convergent validity of the resilience scale for adults (RSA) and the Herth hope scale (HHS) in the prediction of anxiety and depression.

PubMed

Morote, Roxanna; Hjemdal, Odin; Krysinska, Karolina; Martinez Uribe, Patricia; Corveleyn, Jozef

2017-10-27

Hope and resilience protect against inner vulnerabilities or harsh life circumstances; they explain individual differences in physical or mental health outcomes under high stress. They have been studied in complementary or competing theoretical frameworks; therefore, the study of measures of hope and resilience should be undertaken prior to explore if they are truly value-added for research. This study investigates the convergent and incremental validity of the Resilience Scale for Adults (RSA) and the Herth Hope Scale (HHS), in the prediction of anxiety and depression (HSCL-25). Participants in this community-based sample are 762 adults from 18 to 74 years old. They answered the RSA, HHS, Spanish Language Stressful Life-Events Checklist (SL-SLE), and the Hopkins Symptom Checklist-25 (HSCL-25). Incremental validity analyses combined hierarchical regression and structural equation models (SEM). First, hierarchical regression models were compared based on three criteria (R 2 Diff., ΔF, and semi-partial r), then the direct effect of resilience on affective symptoms was compared with the mediated effect of resilience on affective symptoms through hope. The hierarchical models showed that (1) hope and resilience account significantly for the variance of affective symptoms above age, sex, and life-stress; (2) Resilience Total score has greater incremental validity than positive scales of HHS Hope; and (3) RSA Total score, HHS Optimism/Spiritual support, Stressful life-events and sex are unique predictors of affective symptoms. The SEM analyses verified a stronger direct effect of resilience in the prediction of affective symptoms above the significant partial mediated effect of resilience through hope. Additionally, results show that age and better educational opportunities were associated with protection (i.e. resilience and hope) and emotional well-being (i.e. affective symptoms and hopelessness). Women showed higher scores in social competences and resources (RSA

MEDICAID and SCHIP: Recent HHS Approvals of Demonstration Waiver Projects Raise Concerns

DTIC Science & Technology

2002-07-01

Medicaid beneficiaries. However, because the demonstration defines adults as age 19 and older , HHS granted Utah a waiver of the EPSDT requirement...SCHIP children, at or below 200% FPL Adults age 19 and older below 150% FPL, including childless adults from state-only program, and parents... Seniors age 65 and older , at or below 200% FPL, not otherwise eligible for Medicaid; many from state-only pharmacy benefit program Number of

78 FR 32255 - HHS-Operated Risk Adjustment Data Validation Stakeholder Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-29

...-Operated Risk Adjustment Data Validation Stakeholder Meeting AGENCY: Centers for Medicare & Medicaid... Act HHS-operated risk adjustment data validation process. The purpose of this public meeting is to... interested parties about key HHS policy considerations pertaining to the HHS-operated risk adjustment data...

76 FR 14402 - Draft Action Plan-A Public Health Action Plan To Combat Antimicrobial Resistance

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-16

...-2011-0002] Draft Action Plan--A Public Health Action Plan To Combat Antimicrobial Resistance AGENCY: Centers for Disease Control and Prevention (CDC), Department of Health and Human Services (DHHS). ACTION... requesting public comment on the draft A Public Health Action Plan to Combat Antimicrobial Resistance. HHS...

45 CFR 605.0 - Adoption of HHS regulations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Provisions § 605.0 Adoption of HHS regulations. The regulations of the Department of Health and Human... 45 Public Welfare 3 2011-10-01 2011-10-01 false Adoption of HHS regulations. 605.0 Section 605.0... phrase appears in § 605.4(b)(5) and in Subpart C (§§ 605.21 through 605.23). The date for compliance with...

24 CFR 232.620 - Determination of compliance by HHS.

Code of Federal Regulations, 2013 CFR

2013-04-01

... of Fire Safety Equipment Special Requirements § 232.620 Determination of compliance by HHS. An... the fire safety equipment has been installed, will be in compliance with the HHS requirements for fire... Security Act upon the installation of the fire safety equipment. The architectural exhibits, as approved...

24 CFR 232.620 - Determination of compliance by HHS.

Code of Federal Regulations, 2011 CFR

2011-04-01

... AUTHORITIES MORTGAGE INSURANCE FOR NURSING HOMES, INTERMEDIATE CARE FACILITIES, BOARD AND CARE HOMES, AND... of Fire Safety Equipment Special Requirements § 232.620 Determination of compliance by HHS. An... the fire safety equipment has been installed, will be in compliance with the HHS requirements for fire...

42 CFR 64.9 - Other HHS regulations that apply.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Other HHS regulations that apply. 64.9 Section 64.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL LIBRARY OF MEDICINE TRAINING GRANTS § 64.9 Other HHS regulations that apply. Several...

42 CFR 64.9 - Other HHS regulations that apply.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Other HHS regulations that apply. 64.9 Section 64.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL LIBRARY OF MEDICINE TRAINING GRANTS § 64.9 Other HHS regulations that apply. Several...

42 CFR 64.9 - Other HHS regulations that apply.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Other HHS regulations that apply. 64.9 Section 64.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL LIBRARY OF MEDICINE TRAINING GRANTS § 64.9 Other HHS regulations that apply. Several...

42 CFR 420.303 - HHS criteria for requesting books, documents, and records.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 3 2013-10-01 2013-10-01 false HHS criteria for requesting books, documents, and... Books, Documents, and Records of Subcontractors § 420.303 HHS criteria for requesting books, documents, and records. HHS will generally request books, documents, and records from a subcontractor only if one...

42 CFR 420.303 - HHS criteria for requesting books, documents, and records.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 3 2012-10-01 2012-10-01 false HHS criteria for requesting books, documents, and... Books, Documents, and Records of Subcontractors § 420.303 HHS criteria for requesting books, documents, and records. HHS will generally request books, documents, and records from a subcontractor only if one...

42 CFR 420.303 - HHS criteria for requesting books, documents, and records.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 3 2014-10-01 2014-10-01 false HHS criteria for requesting books, documents, and... Books, Documents, and Records of Subcontractors § 420.303 HHS criteria for requesting books, documents, and records. HHS will generally request books, documents, and records from a subcontractor only if one...

78 FR 73195 - Privacy Act of 1974: CMS Computer Matching Program Match No. 2013-01; HHS Computer Matching...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-05

.... Description of the Matching Program A. General The Computer Matching and Privacy Protection Act of 1988 (Pub... 1974: CMS Computer Matching Program Match No. 2013-01; HHS Computer Matching Program Match No. 1312...). ACTION: Notice of Computer Matching Program (CMP). SUMMARY: In accordance with the requirements of the...

77 FR 28883 - Draft Public Health Action Plan-A National Public Health Action Plan for the Detection...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-16

...-2012-0004] Draft Public Health Action Plan--A National Public Health Action Plan for the Detection...), Department of Health and Human Services (HHS). ACTION: Notice of availability and request for public comment..., Division of Reproductive Health, Attn: National Public Health Action Plan for the Detection, Prevention...

77 FR 38296 - Draft Public Health Action Plan-A National Public Health Action Plan for the Detection...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-27

...-2012-0004] Draft Public Health Action Plan--A National Public Health Action Plan for the Detection...), Department of Health and Human Services (HHS). ACTION: Extension of public comment period. SUMMARY: On May 16... National Public Health Action Plan for the Detection, Prevention, and Management of Infertility (77 FR...

76 FR 3637 - Annual Update of the HHS Poverty Guidelines

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-20

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Annual Update of the HHS Poverty... update of the Department of Health and Human Services (HHS) poverty guidelines to account for last... program. For information about poverty figures for immigration forms, the Hill-Burton Uncompensated...

77 FR 4034 - Annual Update of the HHS Poverty Guidelines

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-26

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Annual Update of the HHS Poverty... update of the Department of Health and Human Services (HHS) poverty guidelines to account for last... program. For information about poverty figures for immigration forms, the Hill-Burton Uncompensated...

78 FR 5182 - Annual Update of the HHS Poverty Guidelines

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-24

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Annual Update of the HHS Poverty... update of the Department of Health and Human Services (HHS) poverty guidelines to account for last... program. For information about poverty figures for immigration forms, the Hill-Burton Uncompensated...

42 CFR 52d.8 - Other HHS regulations that apply.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Other HHS regulations that apply. 52d.8 Section 52d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL CANCER INSTITUTE CLINICAL CANCER EDUCATION PROGRAM § 52d.8 Other HHS regulations that apply. Several...

42 CFR 52c.7 - Other HHS regulations that apply.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Other HHS regulations that apply. 52c.7 Section 52c.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MINORITY BIOMEDICAL RESEARCH SUPPORT PROGRAM § 52c.7 Other HHS regulations that apply. Several other regulations and...

42 CFR 52c.7 - Other HHS regulations that apply.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Other HHS regulations that apply. 52c.7 Section 52c.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MINORITY BIOMEDICAL RESEARCH SUPPORT PROGRAM § 52c.7 Other HHS regulations that apply. Several other regulations and...

42 CFR 52c.7 - Other HHS regulations that apply.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Other HHS regulations that apply. 52c.7 Section 52c.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MINORITY BIOMEDICAL RESEARCH SUPPORT PROGRAM § 52c.7 Other HHS regulations that apply. Several other regulations and...

42 CFR 52d.8 - Other HHS regulations that apply.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Other HHS regulations that apply. 52d.8 Section 52d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL CANCER INSTITUTE CLINICAL CANCER EDUCATION PROGRAM § 52d.8 Other HHS regulations that apply. Several...

42 CFR 59a.17 - Other HHS regulations that apply.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Other HHS regulations that apply. 59a.17 Section 59a.17 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL LIBRARY OF MEDICINE GRANTS Establishment of Regional Medical Libraries § 59a.17 Other HHS regulations that...

42 CFR 59a.17 - Other HHS regulations that apply.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Other HHS regulations that apply. 59a.17 Section 59a.17 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL LIBRARY OF MEDICINE GRANTS Establishment of Regional Medical Libraries § 59a.17 Other HHS regulations that...

42 CFR 59a.17 - Other HHS regulations that apply.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Other HHS regulations that apply. 59a.17 Section 59a.17 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL LIBRARY OF MEDICINE GRANTS Establishment of Regional Medical Libraries § 59a.17 Other HHS regulations that...

42 CFR 59a.17 - Other HHS regulations that apply.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Other HHS regulations that apply. 59a.17 Section 59a.17 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL LIBRARY OF MEDICINE GRANTS Establishment of Regional Medical Libraries § 59a.17 Other HHS regulations that...

42 CFR 52d.8 - Other HHS regulations that apply.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Other HHS regulations that apply. 52d.8 Section 52d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL CANCER INSTITUTE CLINICAL CANCER EDUCATION PROGRAM § 52d.8 Other HHS regulations that apply. Several...

42 CFR 52d.8 - Other HHS regulations that apply.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Other HHS regulations that apply. 52d.8 Section 52d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL CANCER INSTITUTE CLINICAL CANCER EDUCATION PROGRAM § 52d.8 Other HHS regulations that apply. Several...

42 CFR 52d.8 - Other HHS regulations that apply.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Other HHS regulations that apply. 52d.8 Section 52d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL CANCER INSTITUTE CLINICAL CANCER EDUCATION PROGRAM § 52d.8 Other HHS regulations that apply. Several...

Study on Interactions between the Major Apple Valsa Canker Pathogen Valsa mali and Its Biocontrol Agent Saccharothrix yanglingensis Hhs.015 Using RT-qPCR

PubMed Central

Fan, Dongying; Li, Yanfang; Zhao, Lingyun; Li, Zhengpeng; Huang, Lili; Yan, Xia

2016-01-01

The mechanism of biocontrol agent Saccharothrix yanglingensis Hhs.015 action against Valsa mali, a major apple Valsa canker pathogen, was examined using a novel, sensitive (minimum detection limit 100 pg/μL) and reliably RT-qPCR technique. Prior to lesion formation, total concentration of V. mali in the bark showed a significant decrease (p<0.05) after 24 h of Hhs.015 treatment. This was more pronounced at 48 and 96 h post treatment. After lesion formation, levels of V. mali remained constant at the boundary between infected and uninfected bark tissues, although the relative expansion rate of the lesion was significantly reduced (p<0.05). Gene expression levels of endo-polygalacturonase, a marker for fungal pathogenicity, were sharply reduced while host induced resistance callose synthase levels increased significantly (p<0.05) at the boundary bark at 9 d after Hhs.015 treatment. The results showed that biocontrol agent Hhs.015 prevented infection of V. mali by inhibiting pathogen growth, down-regulating pathogenicity factor expression and inducing a high level of host resistance. PMID:27611855

Five Years of HHS Home Health Care Evaluations: Using Evaluation to Change National Policy

ERIC Educational Resources Information Center

Brandon, Paul R.; Smith, Nick L.; Grob, George F.

2012-01-01

In 1997, American Evaluation Association member George Grob, now retired from the U.S. Department of Health and Human Services (HHS) and currently President of the Center for Public Program Evaluation, made a testimony on Medicare home health care fraud and abuse before the U.S. Senate Special Committee on Aging. The occasion was to announce the…

Effects of aging on action-intentional programming.

PubMed

Shoraka, Ali R; Otzel, Dana M; M Zilli, Eduardo; Finney, Glen R; Doty, Leilani; Falchook, Adam D; Heilman, Kenneth M

2018-03-01

Action-intentional programs control "when" we initiate, inhibit, continue, and stop motor actions. The purpose of this study was to learn if there are changes in the action-intentional system with healthy aging, and if these changes are asymmetrical (right versus left upper limb) or related to impaired interhemispheric communication. We administered tests of action-intention to 41 middle-aged and older adults (61.9 ± 12.3 years). Regression analyses revealed that older age predicted a decrement in performance for tests of crossed motor response inhibition as well as slower motor initiation with the left hand. Changes in action-intention with aging appear to be related to alterations of interhemispheric communication and/or age-related right hemisphere dysfunction; however, further research is needed to identify the mechanisms for age-related changes in the brain networks that mediate action-intention.

Implementing the Executive Order: HHS Takes Lead in Developing Comprehensive Plan.

ERIC Educational Resources Information Center

Ambler, Marjane

1999-01-01

Describes the Department of Health and Human Services' (HHS) efforts to develop a comprehensive five-year plan that will change the way all HHS agencies deal with tribal colleges. Summarizes the conference held in Phoenix in January 1998 that brought tribal college presidents and departmental officials together to find common ground for developing…

25 CFR 41.6 - HHS participation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION GRANTS TO TRIBALLY CONTROLLED COMMUNITY COLLEGES AND NAVAJO COMMUNITY COLLEGE Tribally Controlled Community Colleges § 41.6 HHS participation. The Assistant... Education, Department of Health and Human Services, and to revise such agreement as necessary, to assist the...

75 FR 3734 - 2009 HHS Poverty Guidelines Extended Until March 1, 2010

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-22

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary 2009 HHS Poverty Guidelines... 2009 Department of Health and Human Services (HHS) poverty guidelines will remain in effect until updated 2010 poverty guidelines are published, which shall not take place before March 1, 2010. DATES...

42 CFR 420.303 - HHS criteria for requesting books, documents, and records.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false HHS criteria for requesting books, documents, and... HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM PROGRAM INTEGRITY: MEDICARE Access to Books, Documents, and Records of Subcontractors § 420.303 HHS criteria for requesting books, documents, and records...

45 CFR 153.630 - Data validation requirements when HHS operates risk adjustment.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 1 2013-10-01 2013-10-01 false Data validation requirements when HHS operates... Program § 153.630 Data validation requirements when HHS operates risk adjustment. (a) General requirement... performed on its risk adjustment data as described in this section. (b) Initial validation audit. (1) An...

45 CFR 153.630 - Data validation requirements when HHS operates risk adjustment.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 1 2014-10-01 2014-10-01 false Data validation requirements when HHS operates... Program § 153.630 Data validation requirements when HHS operates risk adjustment. (a) General requirement... performed on its risk adjustment data as described in this section. (b) Initial validation audit. (1) An...

48 CFR 301.603-72 - FAC-C and HHS SAC certification requirements.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false FAC-C and HHS SAC... Responsibilities 301.603-72 FAC-C and HHS SAC certification requirements. (a) The FAC-C certification program is... thereunder are not required to re-take training courses, but shall follow FAC-C training requirements when...

48 CFR 301.603-72 - FAC-C and HHS SAC certification requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false FAC-C and HHS SAC... Responsibilities 301.603-72 FAC-C and HHS SAC certification requirements. (a) The FAC-C certification program is... thereunder are not required to re-take training courses, but shall follow FAC-C training requirements when...

48 CFR 301.603-72 - FAC-C and HHS SAC certification requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false FAC-C and HHS SAC... Responsibilities 301.603-72 FAC-C and HHS SAC certification requirements. (a) The FAC-C certification program is... thereunder are not required to re-take training courses, but shall follow FAC-C training requirements when...

48 CFR 301.603-72 - FAC-C and HHS SAC certification requirements.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false FAC-C and HHS SAC... Responsibilities 301.603-72 FAC-C and HHS SAC certification requirements. (a) The FAC-C certification program is... thereunder are not required to re-take training courses, but shall follow FAC-C training requirements when...

42 CFR 52e.8 - Other HHS regulations and policies that apply.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Other HHS regulations and policies that apply. 52e.8 Section 52e.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL HEART, LUNG, AND BLOOD INSTITUTE GRANTS FOR PREVENTION AND CONTROL PROJECTS § 52e.8 Other HHS...

42 CFR 52e.8 - Other HHS regulations and policies that apply.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Other HHS regulations and policies that apply. 52e.8 Section 52e.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL HEART, LUNG, AND BLOOD INSTITUTE GRANTS FOR PREVENTION AND CONTROL PROJECTS § 52e.8 Other HHS...

42 CFR 52e.8 - Other HHS regulations and policies that apply.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Other HHS regulations and policies that apply. 52e.8 Section 52e.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL HEART, LUNG, AND BLOOD INSTITUTE GRANTS FOR PREVENTION AND CONTROL PROJECTS § 52e.8 Other HHS...

42 CFR 52e.8 - Other HHS regulations and policies that apply.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Other HHS regulations and policies that apply. 52e.8 Section 52e.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL HEART, LUNG, AND BLOOD INSTITUTE GRANTS FOR PREVENTION AND CONTROL PROJECTS § 52e.8 Other HHS...

42 CFR 52e.8 - Other HHS regulations and policies that apply.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Other HHS regulations and policies that apply. 52e.8 Section 52e.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL HEART, LUNG, AND BLOOD INSTITUTE GRANTS FOR PREVENTION AND CONTROL PROJECTS § 52e.8 Other HHS...

Green Team Recognized with HHS Green Champion Award Honorable Mention | Poster

Cancer.gov

Courtesy of the NCI at Frederick Green Team The NCI at Frederick Green Team received a Department of Health and Human Services (HHS) Green Champion Award honorable mention in June for the team’s plant swap initiative, begun in October 2012.  “The Green Team has been doing a great job this past year, and it is wonderful that their efforts have been recognized by the HHS through

24 CFR 581.10 - Action on approved applications.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Action on approved applications... HOUSING AND URBAN DEVELOPMENT COMMUNITY FACILITIES USE OF FEDERAL REAL PROPERTY TO ASSIST THE HOMELESS § 581.10 Action on approved applications. (a) Unutilized and underutilized properties. (1) When HHS...

24 CFR 581.10 - Action on approved applications.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 3 2011-04-01 2010-04-01 true Action on approved applications. 581... URBAN DEVELOPMENT COMMUNITY FACILITIES USE OF FEDERAL REAL PROPERTY TO ASSIST THE HOMELESS § 581.10 Action on approved applications. (a) Unutilized and underutilized properties. (1) When HHS approves an...

45 CFR 158.607 - Factors HHS uses to determine the amount of penalty.

Code of Federal Regulations, 2012 CFR

2012-10-01

... level of financial and other impacts on affected individuals. (3) Other factors as justice may require. ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Factors HHS uses to determine the amount of... Civil Penalties § 158.607 Factors HHS uses to determine the amount of penalty. In determining the amount...

45 CFR 158.607 - Factors HHS uses to determine the amount of penalty.

Code of Federal Regulations, 2014 CFR

2014-10-01

... level of financial and other impacts on affected individuals. (3) Other factors as justice may require. ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Factors HHS uses to determine the amount of... Civil Penalties § 158.607 Factors HHS uses to determine the amount of penalty. In determining the amount...

45 CFR 158.607 - Factors HHS uses to determine the amount of penalty.

Code of Federal Regulations, 2013 CFR

2013-10-01

... level of financial and other impacts on affected individuals. (3) Other factors as justice may require. ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Factors HHS uses to determine the amount of... Civil Penalties § 158.607 Factors HHS uses to determine the amount of penalty. In determining the amount...

42 CFR 51d.8 - Which other HHS regulations apply to these awards?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false Which other HHS regulations apply to these awards? 51d.8 Section 51d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MENTAL HEALTH AND SUBSTANCE ABUSE EMERGENCY RESPONSE PROCEDURES § 51d.8 Which other HHS...

42 CFR 51d.8 - Which other HHS regulations apply to these awards?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false Which other HHS regulations apply to these awards? 51d.8 Section 51d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MENTAL HEALTH AND SUBSTANCE ABUSE EMERGENCY RESPONSE PROCEDURES § 51d.8 Which other HHS...

42 CFR 51d.8 - Which other HHS regulations apply to these awards?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false Which other HHS regulations apply to these awards? 51d.8 Section 51d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS MENTAL HEALTH AND SUBSTANCE ABUSE EMERGENCY RESPONSE PROCEDURES § 51d.8 Which other HHS...

The HHS-HCC Risk Adjustment Model for Individual and Small Group Markets under the Affordable Care Act

PubMed Central

Kautter, John; Pope, Gregory C; Ingber, Melvin; Freeman, Sara; Patterson, Lindsey; Cohen, Michael; Keenan, Patricia

2014-01-01

Beginning in 2014, individuals and small businesses are able to purchase private health insurance through competitive Marketplaces. The Affordable Care Act (ACA) provides for a program of risk adjustment in the individual and small group markets in 2014 as Marketplaces are implemented and new market reforms take effect. The purpose of risk adjustment is to lessen or eliminate the influence of risk selection on the premiums that plans charge. The risk adjustment methodology includes the risk adjustment model and the risk transfer formula. This article is the second of three in this issue of the Review that describe the Department of Health and Human Services (HHS) risk adjustment methodology and focuses on the risk adjustment model. In our first companion article, we discuss the key issues and choices in developing the methodology. In this article, we present the risk adjustment model, which is named the HHS-Hierarchical Condition Categories (HHS-HCC) risk adjustment model. We first summarize the HHS-HCC diagnostic classification, which is the key element of the risk adjustment model. Then the data and methods, results, and evaluation of the risk adjustment model are presented. Fifteen separate models are developed. For each age group (adult, child, and infant), a model is developed for each cost sharing level (platinum, gold, silver, and bronze metal levels, as well as catastrophic plans). Evaluation of the risk adjustment models shows good predictive accuracy, both for individuals and for groups. Lastly, this article provides examples of how the model output is used to calculate risk scores, which are an input into the risk transfer formula. Our third companion paper describes the risk transfer formula. PMID:25360387

42 CFR 73.3 - HHS select agents and toxins.

Code of Federal Regulations, 2010 CFR

2010-10-01

... been genetically modified. (d) HHS select agents or toxins that meet any of the following criteria are... Recombinant Organisms: (1) Nucleic acids that can produce infectious forms of any of the select agent viruses...

Nondiscrimination on the basis of handicap--Office of the Secretary, HHS. Interim final rule.

PubMed

1983-03-07

The interim final rule modifies existing regulations to meet the exigent needs that can arise when a handicapped infant is discriminatorily denied food or other medical care. Three current regulatory provisions are modified to allow timely reporting of violations, expeditious investigation, and immediate enforcement action when necessary to protect a handicapped infant whose life is endangered by discrimination in a program or activity receiving federal financial assistance. Recipients that provide health care to infants will be required to post a conspicuous notice in locations that provide such care. The notice will describe the protections under federal law against discrimination toward the handicapped, and will provide a contact point in the Department of HHS for reporting violations immediately by telephone.

HCV Health Policy Developments in Response to the National Viral Hepatitis Action Plan: A Brief Update.

PubMed

Guo, Yuqi; Sims, Omar T

2017-02-17

Hepatitis C virus (HCV) kills 366,000 people worldwide and 17,000 people in the United States each year. In 2011, the U.S. Department of Health and Human Services (HHS) published a national viral hepatitis action plan to control and combat HCV in the United States. This article provides a brief update of HCV health policy developments that have emerged since publication of HHS's national viral hepatitis action plan and concludes with a discussion of the public health impact of these recent HCV health policy developments.

45 CFR 12a.10 - Action on approved applications.

Code of Federal Regulations, 2011 CFR

2011-10-01

... REAL PROPERTY TO ASSIST THE HOMELESS § 12a.10 Action on approved applications. (a) Unutilized and underutilized properties. (1) When HHS approves an application, it will so notify the applicant and forward a... 45 Public Welfare 1 2011-10-01 2011-10-01 false Action on approved applications. 12a.10 Section...

45 CFR 12a.10 - Action on approved applications.

Code of Federal Regulations, 2010 CFR

2010-10-01

... REAL PROPERTY TO ASSIST THE HOMELESS § 12a.10 Action on approved applications. (a) Unutilized and underutilized properties. (1) When HHS approves an application, it will so notify the applicant and forward a... 45 Public Welfare 1 2010-10-01 2010-10-01 false Action on approved applications. 12a.10 Section...

75 FR 60768 - Single-Ingredient Oral Colchicine Products; Enforcement Action Dates

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-01

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0257] Single-Ingredient Oral Colchicine Products; Enforcement Action Dates AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA or agency) is announcing its...

48 CFR 301.603-74 - Requirement for retention of FAC-C and HHS SAC certification.

Code of Federal Regulations, 2014 CFR

2014-10-01

... of FAC-C and HHS SAC certification. 301.603-74 Section 301.603-74 Federal Acquisition Regulations..., Contracting Authority, and Responsibilities 301.603-74 Requirement for retention of FAC-C and HHS SAC certification. To maintain FAC-C certification, all warranted Contracting Officers, regardless of series, as...

48 CFR 301.603-74 - Requirement for retention of FAC-C and HHS SAC certification.

Code of Federal Regulations, 2013 CFR

2013-10-01

... of FAC-C and HHS SAC certification. 301.603-74 Section 301.603-74 Federal Acquisition Regulations..., Contracting Authority, and Responsibilities 301.603-74 Requirement for retention of FAC-C and HHS SAC certification. To maintain FAC-C certification, all warranted Contracting Officers, regardless of series, as...

48 CFR 301.603-74 - Requirement for retention of FAC-C and HHS SAC certification.

Code of Federal Regulations, 2012 CFR

2012-10-01

... of FAC-C and HHS SAC certification. 301.603-74 Section 301.603-74 Federal Acquisition Regulations..., Contracting Authority, and Responsibilities 301.603-74 Requirement for retention of FAC-C and HHS SAC certification. To maintain FAC-C certification, all warranted Contracting Officers, regardless of series, as...

48 CFR 301.603-74 - Requirement for retention of FAC-C and HHS SAC certification.

Code of Federal Regulations, 2011 CFR

2011-10-01

... of FAC-C and HHS SAC certification. 301.603-74 Section 301.603-74 Federal Acquisition Regulations..., Contracting Authority, and Responsibilities 301.603-74 Requirement for retention of FAC-C and HHS SAC certification. To maintain FAC-C certification, all warranted Contracting Officers, regardless of series, as...

42 CFR 93.515 - Actions for violating an order or for disruptive conduct.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Actions for violating an order or for disruptive... Misconduct and HHS Administrative Actions Hearing Process § 93.515 Actions for violating an order or for disruptive conduct. (a) The ALJ may take action against any party in the proceeding for violating an order or...

75 FR 45628 - Delayed Update of the HHS Poverty Guidelines for the Remainder of 2010

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-03

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Delayed Update of the HHS Poverty...: This notice provides a delayed update of the Department of Health and Human Services (HHS) poverty guidelines for the remainder of 2010, and until the 2011 poverty guidelines are published, which is expected...

42 CFR 1007.21 - Other applicable HHS regulations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... the Department of Health and Human Services, Effectuation of title VI of the Civil Rights Act of 1964... 42 Public Health 5 2011-10-01 2011-10-01 false Other applicable HHS regulations. 1007.21 Section 1007.21 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

42 CFR 1007.21 - Other applicable HHS regulations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... the Department of Health and Human Services, Effectuation of title VI of the Civil Rights Act of 1964... 42 Public Health 5 2013-10-01 2013-10-01 false Other applicable HHS regulations. 1007.21 Section 1007.21 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

42 CFR 1007.21 - Other applicable HHS regulations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the Department of Health and Human Services, Effectuation of title VI of the Civil Rights Act of 1964... 42 Public Health 5 2010-10-01 2010-10-01 false Other applicable HHS regulations. 1007.21 Section 1007.21 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

42 CFR 1007.21 - Other applicable HHS regulations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... the Department of Health and Human Services, Effectuation of title VI of the Civil Rights Act of 1964... 42 Public Health 5 2014-10-01 2014-10-01 false Other applicable HHS regulations. 1007.21 Section 1007.21 Public Health OFFICE OF INSPECTOR GENERAL-HEALTH CARE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

45 CFR 1.1 - Location of HHS regulations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.1... of the Secretary administers are located in Parts 1-99 of Title 45. • Health regulations are located at Parts 1-399 of Title 42. • Health care financing regulations are located at Parts 400-499 of Title...

45 CFR 1.1 - Location of HHS regulations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Public Welfare Department of Health and Human Services GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.1... of the Secretary administers are located in Parts 1-99 of Title 45. • Health regulations are located at Parts 1-399 of Title 42. • Health care financing regulations are located at Parts 400-499 of Title...

45 CFR 1.1 - Location of HHS regulations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.1... of the Secretary administers are located in Parts 1-99 of Title 45. • Health regulations are located at Parts 1-399 of Title 42. • Health care financing regulations are located at Parts 400-499 of Title...

45 CFR 1.1 - Location of HHS regulations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.1... of the Secretary administers are located in Parts 1-99 of Title 45. • Health regulations are located at Parts 1-399 of Title 42. • Health care financing regulations are located at Parts 400-499 of Title...

45 CFR 1.1 - Location of HHS regulations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HHS'S REGULATIONS § 1.1... of the Secretary administers are located in Parts 1-99 of Title 45. • Health regulations are located at Parts 1-399 of Title 42. • Health care financing regulations are located at Parts 400-499 of Title...

Treatment of Diabetic Ketoacidosis (DKA)/Hyperglycemic Hyperosmolar State (HHS): Novel Advances in the Management of Hyperglycemic Crises (UK Versus USA).

PubMed

Dhatariya, Ketan K; Vellanki, Priyathama

2017-05-01

Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are diabetic emergencies that cause high morbidity and mortality. Their treatment differs in the UK and USA. This review delineates the differences in diagnosis and treatment between the two countries. Large-scale studies to determine optimal management of DKA and HHS are lacking. The diagnosis of DKA is based on disease severity in the USA, which differs from the UK. The diagnosis of HHS in the USA is based on total rather than effective osmolality. Unlike the USA, the UK has separate guidelines for DKA and HHS. Treatment of DKA and HHS also differs with respect to timing of fluid and insulin initiation. There is considerable overlap but important differences between the UK and USA guidelines for the management of DKA and HHS. Further research needs to be done to delineate a unifying diagnostic and treatment protocol.

24 CFR 232.620 - Determination of compliance by HHS.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Determination of compliance by HHS. 232.620 Section 232.620 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued) OFFICE OF ASSISTANT SECRETARY FOR HOUSING-FEDERAL HOUSING COMMISSIONER, DEPARTMENT OF...

Household obesity prevention: Take Action--a group-randomized trial.

PubMed

French, Simone A; Gerlach, Anne F; Mitchell, Nathan R; Hannan, Peter J; Welsh, Ericka M

2011-10-01

The purpose of the present study was to evaluate an intervention to prevent weight gain among households (HHs) in the community. Ninety HHs were randomized to intervention or control group for 1 year. Intervention consisted of six face-to-face group sessions, placement of a television (TV) locking device on all home TVs, and home-based intervention activities. Measures were collected in person at baseline and 1 year. Weight, height, eating behaviors, physical activity (PA), and TV viewing were measured among HH members ages ≥ 12 years. Follow-up rate at 1 year was 96%. No significant intervention effects were observed for change in HH BMI-z score. Intervention HHs significantly reduced TV viewing, snacks/sweets intake, and dollars per person spent eating out, and increased (adults only) PA and self-weighing frequency compared with control HHs. A 1 year obesity prevention intervention targeting entire HHs was effective in reducing TV viewing, snack/sweets intake and eating out purchases. Innovative methods are needed to strengthen the home food environment intervention component. Longer intervention durations also need to be evaluated.

45 CFR 153.740 - Failure to comply with HHS-operated risk adjustment and reinsurance data requirements.

Code of Federal Regulations, 2014 CFR

2014-10-01

... adjustment data submission and data storage requirements set forth in §§ 153.610 through 153.630, HHS may... adjustment and reinsurance data requirements. 153.740 Section 153.740 Public Welfare Department of Health and... CORRIDORS, AND RISK ADJUSTMENT UNDER THE AFFORDABLE CARE ACT Distributed Data Collection for HHS-Operated...

42 CFR 50.607 - Other HHS regulations that apply.

Code of Federal Regulations, 2010 CFR

2010-10-01

....607 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS POLICIES OF... Funding Is Sought § 50.607 Other HHS regulations that apply. Several other regulations and policies apply... 45 CFR part 74—Uniform Administrative Requirements for Awards and Subawards to Institutions of Higher...

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

42 CFR 93.501 - Opportunity to contest findings of research misconduct and administrative actions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... misconduct and administrative actions. 93.501 Section 93.501 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT... RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General Information § 93.501 Opportunity to...

42 CFR 87.9 - Which other HHS regulations apply?

Code of Federal Regulations, 2010 CFR

2010-10-01

... assistance through the Department of Health and Human Services effectuation of title VI of the Civil Rights... 42 Public Health 1 2010-10-01 2010-10-01 false Which other HHS regulations apply? 87.9 Section 87.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY...

42 CFR 87.9 - Which other HHS regulations apply?

Code of Federal Regulations, 2014 CFR

2014-10-01

... assistance through the Department of Health and Human Services effectuation of title VI of the Civil Rights... 42 Public Health 1 2014-10-01 2014-10-01 false Which other HHS regulations apply? 87.9 Section 87.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY...

42 CFR 87.9 - Which other HHS regulations apply?

Code of Federal Regulations, 2012 CFR

2012-10-01

... assistance through the Department of Health and Human Services effectuation of title VI of the Civil Rights... 42 Public Health 1 2012-10-01 2012-10-01 false Which other HHS regulations apply? 87.9 Section 87.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY...

42 CFR 87.9 - Which other HHS regulations apply?

Code of Federal Regulations, 2011 CFR

2011-10-01

... assistance through the Department of Health and Human Services effectuation of title VI of the Civil Rights... 42 Public Health 1 2011-10-01 2011-10-01 false Which other HHS regulations apply? 87.9 Section 87.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY...

42 CFR 87.9 - Which other HHS regulations apply?

Code of Federal Regulations, 2013 CFR

2013-10-01

... assistance through the Department of Health and Human Services effectuation of title VI of the Civil Rights... 42 Public Health 1 2013-10-01 2013-10-01 false Which other HHS regulations apply? 87.9 Section 87.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY...

42 CFR 483.405 - Relationship to other HHS regulations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 5 2010-10-01 2010-10-01 false Relationship to other HHS regulations. 483.405 Section 483.405 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION REQUIREMENTS FOR STATES AND LONG TERM CARE FACILITIES Conditions of Participation for Intermediate...

A corticostriatal deficit promotes temporal distortion of automatic action in ageing

PubMed Central

Matamales, Miriam; Skrbis, Zala; Bailey, Matthew R; Balsam, Peter D; Balleine, Bernard W; Götz, Jürgen

2017-01-01

The acquisition of motor skills involves implementing action sequences that increase task efficiency while reducing cognitive loads. This learning capacity depends on specific cortico-basal ganglia circuits that are affected by normal ageing. Here, combining a series of novel behavioural tasks with extensive neuronal mapping and targeted cell manipulations in mice, we explored how ageing of cortico-basal ganglia networks alters the microstructure of action throughout sequence learning. We found that, after extended training, aged mice produced shorter actions and displayed squeezed automatic behaviours characterised by ultrafast oligomeric action chunks that correlated with deficient reorganisation of corticostriatal activity. Chemogenetic disruption of a striatal subcircuit in young mice reproduced age-related within-sequence features, and the introduction of an action-related feedback cue temporarily restored normal sequence structure in aged mice. Our results reveal static properties of aged cortico-basal ganglia networks that introduce temporal limits to action automaticity, something that can compromise procedural learning in ageing. PMID:29058672

42 CFR 64.9 - Other HHS regulations that apply.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the Civil Rights Act of 1964. 45 CFR part 81—Practice and procedure for hearings under 45 CFR part 80... 42 Public Health 1 2010-10-01 2010-10-01 false Other HHS regulations that apply. 64.9 Section 64.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS...

42 CFR 64.9 - Other HHS regulations that apply.

Code of Federal Regulations, 2011 CFR

2011-10-01

... the Civil Rights Act of 1964. 45 CFR part 81—Practice and procedure for hearings under 45 CFR part 80... 42 Public Health 1 2011-10-01 2011-10-01 false Other HHS regulations that apply. 64.9 Section 64.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS...

77 FR 58143 - Interagency Task Force on Antimicrobial Resistance (ITFAR): An Update of A Public Health Action...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-19

...-2012-0011] Interagency Task Force on Antimicrobial Resistance (ITFAR): An Update of A Public Health...), Department of Health and Human Services (HHS). ACTION: Notice of public meeting and request for comments... Federal agencies in accomplishing activities outlined in ``A Public Health Action Plan to Combat...

42 CFR 59a.7 - Other HHS regulations that apply.

Code of Federal Regulations, 2010 CFR

2010-10-01

... assistance through the Department of Health and Human Services—effectuation of title VI of the Civil Rights... 42 Public Health 1 2010-10-01 2010-10-01 false Other HHS regulations that apply. 59a.7 Section 59a.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL...

42 CFR 59a.7 - Other HHS regulations that apply.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Other HHS regulations that apply. 59a.7 Section 59a.7 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL LIBRARY OF MEDICINE GRANTS Grants for Establishing, Expanding, and Improving Basic Resources § 59a.7 Other...

45 CFR 156.1210 - Confirmation of HHS payment and collections reports.

Code of Federal Regulations, 2014 CFR

2014-10-01

... reports. 156.1210 Section 156.1210 Public Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS HEALTH INSURANCE ISSUER STANDARDS UNDER THE AFFORDABLE CARE ACT, INCLUDING STANDARDS RELATED TO EXCHANGES Qualified Health Plan Issuer Responsibilities § 156.1210 Confirmation of HHS...

75 FR 57958 - Solicitation of Written Comments on Draft Tier 2 Strategies/Modules for Inclusion in the “HHS...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-23

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Solicitation of Written Comments on Draft Tier 2...'' AGENCY: Department of Health and Human Services, Office of the Assistant Secretary for Health, Office of....'' To further the HHS mission to protect the health and well-being of the nation, the HHS Steering...

42 CFR 59a.17 - Other HHS regulations that apply.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the Civil Rights Act of 1964 45 CFR part 81—Practice and procedure for hearings under part 80 of this... 42 Public Health 1 2010-10-01 2010-10-01 false Other HHS regulations that apply. 59a.17 Section 59a.17 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS NATIONAL...

45 CFR 153.270 - HHS audits of State-operated reinsurance programs.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 1 2014-10-01 2014-10-01 false HHS audits of State-operated reinsurance programs. 153.270 Section 153.270 Public Welfare Department of Health and Human Services REQUIREMENTS RELATING TO HEALTH CARE ACCESS STANDARDS RELATED TO REINSURANCE, RISK CORRIDORS, AND RISK ADJUSTMENT UNDER THE...

5 CFR 5501.102 - Designation of HHS components as separate agencies.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Designation of HHS components as separate agencies. 5501.102 Section 5501.102 Administrative Personnel DEPARTMENT OF HEALTH AND HUMAN SERVICES SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES § 5501...

5 CFR 5501.102 - Designation of HHS components as separate agencies.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Designation of HHS components as separate agencies. 5501.102 Section 5501.102 Administrative Personnel DEPARTMENT OF HEALTH AND HUMAN SERVICES SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES § 5501...

5 CFR 5501.102 - Designation of HHS components as separate agencies.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Designation of HHS components as separate agencies. 5501.102 Section 5501.102 Administrative Personnel DEPARTMENT OF HEALTH AND HUMAN SERVICES SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES § 5501...

5 CFR 5501.102 - Designation of HHS components as separate agencies.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Designation of HHS components as separate agencies. 5501.102 Section 5501.102 Administrative Personnel DEPARTMENT OF HEALTH AND HUMAN SERVICES SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES § 5501...

5 CFR 5501.102 - Designation of HHS components as separate agencies.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Designation of HHS components as separate agencies. 5501.102 Section 5501.102 Administrative Personnel DEPARTMENT OF HEALTH AND HUMAN SERVICES SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES § 5501...

45 CFR 158.607 - Factors HHS uses to determine the amount of penalty.

Code of Federal Regulations, 2011 CFR

2011-10-01

... entity, including whether, at any time before determination of the current violation(s), HHS or any State found the responsible entity liable for civil or administrative sanctions in connection with a violation...

42 CFR 66.112 - Other HHS regulations and policies that apply.

Code of Federal Regulations, 2013 CFR

2013-10-01

... is subject to change, and interested persons should contact the Office of Science Policy, Office of... 42 Public Health 1 2013-10-01 2013-10-01 false Other HHS regulations and policies that apply. 66... regulations and policies that apply. Several other regulations and policies may apply to individuals and...

42 CFR 66.112 - Other HHS regulations and policies that apply.

Code of Federal Regulations, 2014 CFR

2014-10-01

... is subject to change, and interested persons should contact the Office of Science Policy, Office of... 42 Public Health 1 2014-10-01 2014-10-01 false Other HHS regulations and policies that apply. 66... regulations and policies that apply. Several other regulations and policies may apply to individuals and...

42 CFR 66.112 - Other HHS regulations and policies that apply.

Code of Federal Regulations, 2012 CFR

2012-10-01

... is subject to change, and interested persons should contact the Office of Science Policy, Office of... 42 Public Health 1 2012-10-01 2012-10-01 false Other HHS regulations and policies that apply. 66... regulations and policies that apply. Several other regulations and policies may apply to individuals and...

42 CFR 66.112 - Other HHS regulations and policies that apply.

Code of Federal Regulations, 2010 CFR

2010-10-01

... is subject to change, and interested persons should contact the Office of Science Policy, Office of... 42 Public Health 1 2010-10-01 2010-10-01 false Other HHS regulations and policies that apply. 66... regulations and policies that apply. Several other regulations and policies may apply to individuals and...

42 CFR 66.112 - Other HHS regulations and policies that apply.

Code of Federal Regulations, 2011 CFR

2011-10-01

... is subject to change, and interested persons should contact the Office of Science Policy, Office of... 42 Public Health 1 2011-10-01 2011-10-01 false Other HHS regulations and policies that apply. 66... regulations and policies that apply. Several other regulations and policies may apply to individuals and...

42 CFR 73.5 - Exemptions for HHS select agents and toxins.

Code of Federal Regulations, 2014 CFR

2014-10-01

... the select agent or toxin is reported to CDC or APHIS and to other appropriate authorities when... followed by submission of APHIS/CDC Form 4 within seven calendar days after identification. (ii) For all other HHS select agents or toxins, APHIS/CDC Form 4 must be submitted within seven calendar days after...

42 CFR 73.5 - Exemptions for HHS select agents and toxins.

Code of Federal Regulations, 2013 CFR

2013-10-01

... the select agent or toxin is reported to CDC or APHIS and to other appropriate authorities when... followed by submission of APHIS/CDC Form 4 within seven calendar days after identification. (ii) For all other HHS select agents or toxins, APHIS/CDC Form 4 must be submitted within seven calendar days after...

76 FR 20568 - HHS Plan for Retrospective Review Under Executive Order 13563

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-13

... impact on a substantial number of small businesses as required by the Regulatory Flexibility Act; annual... technologies to facilitate greater participation in the rulemaking process, particularly social media and... actual impact? Public Participation--HHS solicits comments on ways to further engage and increase public...

48 CFR 301.603-72 - FAC-C and HHS SAC certification requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... HUMAN SERVICES GENERAL HHS ACQUISITION REGULATION SYSTEM Career Development, Contracting Authority, and... retention of certification, including the requirement to earn continuous learning points (CLPs). FAC-C... to employees for the first time at a department or agency.) (c) The FAC-C certification is based on...

2 CFR 382.225 - Whom in HHS does a recipient other than an individual notify about a criminal drug conviction?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Whom in HHS does a recipient other than an... DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Other Than Individuals § 382.225 Whom in HHS does a recipient other than an individual notify about a criminal drug conviction? A...

2 CFR 382.300 - Whom in HHS does a recipient who is an individual notify about a criminal drug conviction?

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Whom in HHS does a recipient who is an... DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Who Are Individuals § 382.300 Whom in HHS does a recipient who is an individual notify about a criminal drug conviction? A recipient...

2 CFR 382.300 - Whom in HHS does a recipient who is an individual notify about a criminal drug conviction?

Code of Federal Regulations, 2013 CFR

2013-01-01

... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Whom in HHS does a recipient who is an... DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Who Are Individuals § 382.300 Whom in HHS does a recipient who is an individual notify about a criminal drug conviction? A recipient...

2 CFR 382.225 - Whom in HHS does a recipient other than an individual notify about a criminal drug conviction?

Code of Federal Regulations, 2013 CFR

2013-01-01

... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Whom in HHS does a recipient other than an... DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Other Than Individuals § 382.225 Whom in HHS does a recipient other than an individual notify about a criminal drug conviction? A...

2 CFR 382.225 - Whom in HHS does a recipient other than an individual notify about a criminal drug conviction?

Code of Federal Regulations, 2014 CFR

2014-01-01

... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Whom in HHS does a recipient other than an... DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Other Than Individuals § 382.225 Whom in HHS does a recipient other than an individual notify about a criminal drug conviction? A...

2 CFR 382.300 - Whom in HHS does a recipient who is an individual notify about a criminal drug conviction?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Whom in HHS does a recipient who is an... DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) (Eff. 1-11-2010) Requirements for Recipients Who Are Individuals § 382.300 Whom in HHS does a recipient who is an individual notify about a criminal drug...

2 CFR 382.300 - Whom in HHS does a recipient who is an individual notify about a criminal drug conviction?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Whom in HHS does a recipient who is an... DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Requirements for Recipients Who Are Individuals § 382.300 Whom in HHS does a recipient who is an individual notify about a criminal drug conviction? A recipient...

2 CFR 382.225 - Whom in HHS does a recipient other than an individual notify about a criminal drug conviction?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Whom in HHS does a recipient other than an... DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) (Eff. 1-11-2010) Requirements for Recipients Other Than Individuals § 382.225 Whom in HHS does a recipient other than an individual notify about a criminal drug...

Synthesis and pharmacological evaluation of [(3)H]HS665, a novel, highly selective radioligand for the kappa opioid receptor.

PubMed

Guerrieri, Elena; Mallareddy, Jayapal Reddy; Tóth, Géza; Schmidhammer, Helmut; Spetea, Mariana

2015-03-18

Herein we report the radiolabeling and pharmacological investigation of a novel radioligand, the N-cyclobutylmethyl substituted diphenethylamine [(3)H]HS665, designed to bind selectively to the kappa opioid peptide (KOP) receptor, a target of therapeutic interest for the treatment of a variety of human disorders (i.e., pain, affective disorders, drug addiction, and psychotic disorders). HS665 was prepared in tritium-labeled form by a dehalotritiated method resulting in a specific activity of 30.65 Ci/mmol. Radioligand binding studies were performed to establish binding properties of [(3)H]HS665 to the recombinant human KOP receptor in membranes from Chinese hamster ovary cells stably expressing human KOP receptors (CHOhKOP) and to the native neuronal KOP receptor in guinea pig brain membranes. Binding of [(3)H]HS665 was specific and saturable in both tissue preparations. A single population of high affinity binding sites was labeled by [(3)H]HS665 in membranes from CHOhKOP cells and guinea pig brain with similar equilibrium dissociation constants, Kd, 0.45 and 0.64 nM, respectively. Average receptor density of [(3)H]HS665 recognition sites were 5564 and 154 fmol/mg protein in CHOhKOP cells and guinea pig brain, respectively. This study shows that the new radioligand distinguishes and labels KOP receptors specifically in neuronal and cellular systems expressing KOP receptors, making this molecule a valuable tool in probing structural and functional mechanisms governing ligand-KOP receptor interactions in both a recombinant and native in vitro setting.

Aging Action: A Course in Senior Advocacy in Kansas.

ERIC Educational Resources Information Center

Kansas State Advisory Council on Aging, Topeka.

Skills useful in advocacy of senior citizens' needs are discussed in this manual. The topics included are: (1) the meaning of advocacy; (2) assertiveness training for aging-action; (3) identifying issues; (4) choosing issues; (5) developing a plan of action; (6) organizing; (7) legislative advocacy; (8) criteria to evaluate potential legislative…

48 CFR 301.603-74 - Requirement for retention of FAC-C and HHS SAC certification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... System HEALTH AND HUMAN SERVICES GENERAL HHS ACQUISITION REGULATION SYSTEM Career Development... result in a loss of warrant authority. (Note: The certification programs' continuous learning requirement...

NCI at Frederick Team Receives 2014 HHS Green Champions Award | Poster

Cancer.gov

A team of NCI and Leidos Biomedical Research employees at NCI at Frederick received the Energy and Fleet Management Award, one of the 2014 Department of Health and Human Services (HHS) Green Champions Awards, for comparing the costs and energy usage of two -80°C freezer technologies. This was the first scientific study to be jointly conducted by Leidos Biomedical Research’s

45 CFR 91.11 - Rules against age discrimination.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 45 Public Welfare 1 2013-10-01 2013-10-01 false Rules against age discrimination. 91.11 Section 91... THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM HHS Standards for Determining Age Discrimination § 91.11 Rules against age discrimination. The rules stated in this...

45 CFR 91.11 - Rules against age discrimination.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 45 Public Welfare 1 2012-10-01 2012-10-01 false Rules against age discrimination. 91.11 Section 91... THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM HHS Standards for Determining Age Discrimination § 91.11 Rules against age discrimination. The rules stated in this...

45 CFR 91.11 - Rules against age discrimination.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 45 Public Welfare 1 2014-10-01 2014-10-01 false Rules against age discrimination. 91.11 Section 91... THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM HHS Standards for Determining Age Discrimination § 91.11 Rules against age discrimination. The rules stated in this...

45 CFR 91.11 - Rules against age discrimination.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Rules against age discrimination. 91.11 Section 91... THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM HHS Standards for Determining Age Discrimination § 91.11 Rules against age discrimination. The rules stated in this...

45 CFR 91.11 - Rules against age discrimination.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Rules against age discrimination. 91.11 Section 91... THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM HHS Standards for Determining Age Discrimination § 91.11 Rules against age discrimination. The rules stated in this...

Office of the Assistant Secretary for Preparedness and Response; HHS Public Health Emergency Medical Countermeasures Enterprise implementation plan for chemical, biological, radiological and nuclear threats. Notice.

PubMed

2007-04-23

The United States faces serious public health threats from the deliberate use of weapons of mass destruction (WMD)--chemical, biological, radiological, or nuclear (CBRN)--by hostile States or terrorists, and from naturally emerging infectious diseases that have a potential to cause illness on a scale that could adversely impact national security. Effective strategies to prevent, mitigate, and treat the consequences of CBRN threats is an integral component of our national security strategy. To that end, the United States must be able to rapidly develop, stockpile, and deploy effective medical countermeasures to protect the American people. The HHS Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) has taken a holistic, end-to-end approach that considers multiple aspects of the medical countermeasures mission including research, development, acquisition, storage, maintenance, deployment, and guidance for utilization. Phase one of this approach established the HHS PHEMCE Strategy for Chemical, Biological, Radiological, and Nuclear Threats (HHS PHEMCE Strategy). The HHS PHEMCE Strategy, published in the Federal Register on March 20, 2007, described a framework of strategic policy goals and objectives for identifying medical countermeasure requirements and establishing priorities for medical countermeasure evaluation, development and acquisition. These strategic policy goals and objectives were used to establish the Four Pillars upon which this HHS Public Health Emergency Medical Countermeasures Enterprise Implementation Plan (HHS PHEMCE Implementation Plan) is based. The HHS PHEMCE Implementation Plan considers the full spectrum of medical countermeasures-related activities, including research, development, acquisition, storage/maintenance, deployment, and utilization. The HHS PHEMCE Implementation Plan is consistent with the President's Biodefense for the 21st Century and is aligned with the National Strategy for Medical Countermeasures against

75 FR 4829 - National Institute on Aging; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-29

... Institute on Aging Special Emphasis Panel; Summer Research Training In Aging For Medical Students--NIA T35... review and evaluate contract proposals. Place: National Institute on Aging, Gateway Building, 7201..., Aging Research, National Institutes of Health, HHS) [[Page 4830

75 FR 54159 - National Institute on Aging; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-03

...: National Institute on Aging Special Emphasis Panel, Stem Cells and Genomic Integrity Through Senescense.... 93.866, Aging Research, National Institutes of Health, HHS) Dated: August 26, 2010. Jennifer S...

78 FR 277 - Food and Drug Administration Actions Related to Nicotine Replacement Therapies and Smoking...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-03

... Dependence; Public Hearing; Extension of Comment Period AGENCY: Food and Drug Administration, HHS. ACTION: Notification of public hearing; Extension of comment period. SUMMARY: The Food and Drug Administration (FDA) is... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Part 15 [Docket No...

Never pay retail again. HHS' Thompson says hospitals' discounts to uninsured are legal, as advocates celebrate and hospitals ponder pricing strategies.

PubMed

Jaklevic, Mary Chris

2004-02-23

Consumer advocates praised HHS' assertion that hospitals can legally give discounts to the uninsured, but hospitals expressed more cautious optimism. The declaration fell short of a legal safe harbor, which the AHA requested, and Dara Corrigan, left, HHS' acting principal deputy inspector general, says hospitals will have to be careful. Still, the decision may prompt more hospitals to change billing practices.

48 CFR 353.370-674 - Form HHS 674, Structured Approach Profit/Fee Objective.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Form HHS 674, Structured Approach Profit/Fee Objective. 353.370-674 Section 353.370-674 Federal Acquisition Regulations System..., Structured Approach Profit/Fee Objective. This form is available from local cost advisory personnel or PSC...

Advancing Medication Safety: Establishing a National Action Plan for Adverse Drug Event Prevention.

PubMed

Harris, Yael; Hu, Dale J; Lee, Christine; Mistry, Mishale; York, Andrew; Johnson, Tisha K

2015-08-01

Adverse drug events (ADEs) are important contributors to preventable morbidity and mortality, comprising one third of all hospital adverse events. In response to growing evidence detailing the high prevalence of ADEs, particularly among vulnerable older adults, Congress requested that the Secretary of the Department of Health and Human Services (HHS) convene a Federal Interagency Steering Committee to establish a National Action Plan to focus on ADE prevention. In August 2014, the Office of Disease Prevention and Health Promotion released the final version of the National Action Plan for Adverse Drug Event Prevention. The Action Plan directly supports the goals of the HHS Strategic Plan and the Patient Protection and Affordable Care Act by providing guidance on tracking and preventing ADEs, as well as describing evidence-based tools and resources to enhance medication safety. ADE ACTION PLAN CONTENT: The Federal Interagency Steering Committee focused the Action Plan on ADEs that are clinically significant, account for the greatest number of measurable harms as identified by using existing surveillance tools, and are largely preventable. As such, the decision was made to target three medication classes: anticoagulants, diabetes agents (insulin and oral hypoglycemic agents), and opioids. The Action Plan is organized around four key areas: surveillance; evidence-based prevention; payment, policy incentives, and oversight; and research opportunities to advance medication safety. One measure of the ADE Action Plan's success will be the wider dissemination of information and educational resources to providers and patients (or consumers) regarding the risks associated with medications. Future Action Plan iterations are likely to consider other high-priority medication classes and update the recommendations.

42 CFR 51d.8 - Which other HHS regulations apply to these awards?

Code of Federal Regulations, 2011 CFR

2011-10-01

... title VI of the Civil Rights Act of 1964 45 CFR part 81—Practice and procedure for hearings under part... 42 Public Health 1 2011-10-01 2011-10-01 false Which other HHS regulations apply to these awards? 51d.8 Section 51d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

42 CFR 51d.8 - Which other HHS regulations apply to these awards?

Code of Federal Regulations, 2010 CFR

2010-10-01

... title VI of the Civil Rights Act of 1964 45 CFR part 81—Practice and procedure for hearings under part... 42 Public Health 1 2010-10-01 2010-10-01 false Which other HHS regulations apply to these awards? 51d.8 Section 51d.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

42 CFR 51b.105 - Which other HHS regulations apply to these grants?

Code of Federal Regulations, 2013 CFR

2013-10-01

... effectuation of title VI of the Civil Rights Act of 1964 45 CFR part 81—Practice and procedure for hearings... 42 Public Health 1 2013-10-01 2013-10-01 false Which other HHS regulations apply to these grants? 51b.105 Section 51b.105 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

42 CFR 51b.105 - Which other HHS regulations apply to these grants?

Code of Federal Regulations, 2012 CFR

2012-10-01

... effectuation of title VI of the Civil Rights Act of 1964 45 CFR part 81—Practice and procedure for hearings... 42 Public Health 1 2012-10-01 2012-10-01 false Which other HHS regulations apply to these grants? 51b.105 Section 51b.105 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

42 CFR 51b.105 - Which other HHS regulations apply to these grants?

Code of Federal Regulations, 2011 CFR

2011-10-01

... effectuation of title VI of the Civil Rights Act of 1964 45 CFR part 81—Practice and procedure for hearings... 42 Public Health 1 2011-10-01 2011-10-01 false Which other HHS regulations apply to these grants? 51b.105 Section 51b.105 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

42 CFR 51b.105 - Which other HHS regulations apply to these grants?

Code of Federal Regulations, 2014 CFR

2014-10-01

... effectuation of title VI of the Civil Rights Act of 1964 45 CFR part 81—Practice and procedure for hearings... 42 Public Health 1 2014-10-01 2014-10-01 false Which other HHS regulations apply to these grants? 51b.105 Section 51b.105 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

42 CFR 51b.105 - Which other HHS regulations apply to these grants?

Code of Federal Regulations, 2010 CFR

2010-10-01

... effectuation of title VI of the Civil Rights Act of 1964 45 CFR part 81—Practice and procedure for hearings... 42 Public Health 1 2010-10-01 2010-10-01 false Which other HHS regulations apply to these grants? 51b.105 Section 51b.105 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES...

42 CFR 93.500 - General policy.

Code of Federal Regulations, 2011 CFR

2011-10-01

... MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General... findings of research misconduct and HHS administrative actions, including debarment or suspension, arising... to contest ORI research misconduct findings and HHS administrative actions under this part, including...

42 CFR 93.500 - General policy.

Code of Federal Regulations, 2010 CFR

2010-10-01

... MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions General... findings of research misconduct and HHS administrative actions, including debarment or suspension, arising... to contest ORI research misconduct findings and HHS administrative actions under this part, including...

Rhetoric to action: a study of stakeholder perceptions of aging well in two local communities.

PubMed

Everingham, Jo-Anne; Lui, Chi-Wai; Bartlett, Helen; Warburton, Jeni; Cuthill, Michael

2010-11-01

This qualitative study of local perceptions of policy goals and action in relation to aging reports 31 stakeholder interviews within 2 Australian communities exploring (a) the meaning of aging well; and (b) preferred policy actions to achieve positive aging outcomes. Findings suggest that community perceptions of aging well are broadly consistent with the goals of national and international policy frameworks in focusing on 3 dimensions--health, social engagement, and security. Further, participants believe that achievement of positive aging outcomes requires a mix of self-help, community action, and government intervention--particularly government support and encouragement for aging well initiatives.

42 CFR 93.517 - The hearing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing... committed research misconduct and if the HHS administrative actions, including any debarment or suspension... research misconduct and the proposed HHS administrative actions. The ALJ does not review the institution's...

42 CFR 93.517 - The hearing.

Code of Federal Regulations, 2011 CFR

2011-10-01

... MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing... committed research misconduct and if the HHS administrative actions, including any debarment or suspension... research misconduct and the proposed HHS administrative actions. The ALJ does not review the institution's...

Chelation: A Fundamental Mechanism of Action of AGE Inhibitors, AGE Breakers, and Other Inhibitors of Diabetes Complications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nagai, Rhoji; Murray, David B.; Metz, Thomas O.

2012-03-01

Advanced glycation or glycoxidation end-products (AGE) increase in tissue proteins with age, and their rate of accumulation is increased in diabetes, nephropathy and inflammatory diseases. AGE inhibitors include a range of compounds that are proposed to act by trapping carbonyl and dicarbonyl intermediates in AGE formation. However, some among the newer generation of AGE inhibitors lack reactive functional groups that would trap reaction intermediates, indicating an alternative mechanism of action. We propose that AGE inhibitors function primarily as chelators, inhibiting metal-catalyzed oxidation reactions. The AGE-inhibitory activity of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers is also consistent with their chelatingmore » activity. Finally, compounds described as AGE breakers, or their hydrolysis products, also have strong chelating activity, suggesting that these compounds also act through their chelating activity. We conclude that chelation is the common, and perhaps the primary, mechanism of action of AGE inhibitors and breakers, and that chronic, mild chelation therapy should prove useful in treatment of diabetes and age-related diseases characterized by oxidative stress, inflammation and increased chemical modification of tissue proteins by advanced glycoxidation and lipoxidation end-products.« less

Understanding school-age obesity: through participatory action research.

PubMed

DiNapoli, Pamela P; Lewis, James B

2008-01-01

This study aimed to assess current levels of overweight (obesity) and fitness among school students using objective data. School-based action research teams were recruited statewide by the New Hampshire Healthy Schools Coalition, the state team of the National Action for Healthy Kids Coalition. Action teams consisted of a physical education teacher, a school nurse, and a school administrator. Data were collected from 6,511 student participants aged 6 to 14 years, which was a representative cross-section from New Hampshire school districts. Key variables of interest in the study were body mass index, and ability to pass five fitness tests using FITNESSGRAM. Pearson's correlation was used to assess the relationships among body mass index, age, gender, and the percent of students that passed FITNESSGRAM tests. The ability of participants to pass the FITNESSGRAM tests declined markedly with age and differed between boys and girls, although the healthy fitness zones for any particular test was lower for girls. Body mass index was significantly negatively correlated with performance on all tests. Age was also statistically negatively correlated with performance on all tests; the relationship between gender and performance on the tests was less striking. Results reflected an increase in the prevalence of overweight school children, even in New Hampshire, which is purported to be one of the healthiest states in the nation. Results offered evidence that body mass index is a valid proxy measure for fitness levels and that fitness programs are necessary to effectively combat the obesity epidemic. Evidence-based changes need to be implemented to address obesity-related factors in schools, because children spend many of their waking hours in that setting. Physical activity during recess and physical education classes could help to increase energy expenditure and develop sound minds and bodies. Schools should consider the development of school-based wellness teams to advise and

42 CFR 59.10 - What other HHS regulations apply to grants under this subpart?

Code of Federal Regulations, 2010 CFR

2010-10-01

... assistance through the Department of Health and Human Services effectuation of Title VI of the Civil Rights... 42 Public Health 1 2010-10-01 2010-10-01 false What other HHS regulations apply to grants under this subpart? 59.10 Section 59.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN...

42 CFR 59.10 - What other HHS regulations apply to grants under this subpart?

Code of Federal Regulations, 2011 CFR

2011-10-01

... assistance through the Department of Health and Human Services effectuation of Title VI of the Civil Rights... 42 Public Health 1 2011-10-01 2011-10-01 false What other HHS regulations apply to grants under this subpart? 59.10 Section 59.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN...

42 CFR 59.10 - What other HHS regulations apply to grants under this subpart?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 42 Public Health 1 2012-10-01 2012-10-01 false What other HHS regulations apply to grants under this subpart? 59.10 Section 59.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Project Grants for Family Planning Services § 59.10...

42 CFR 59.10 - What other HHS regulations apply to grants under this subpart?

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 1 2013-10-01 2013-10-01 false What other HHS regulations apply to grants under this subpart? 59.10 Section 59.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Project Grants for Family Planning Services § 59.10...

42 CFR 59.10 - What other HHS regulations apply to grants under this subpart?

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 1 2014-10-01 2014-10-01 false What other HHS regulations apply to grants under this subpart? 59.10 Section 59.10 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS GRANTS FOR FAMILY PLANNING SERVICES Project Grants for Family Planning Services § 59.10...

77 FR 56855 - National Institute on Aging; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-14

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... Special Emphasis Panel; Oxidative Stress and Aging. Date: November 8, 2012. Time: 11:00 a.m. to 3:00 p.m.... 93.866, Aging Research, National Institutes of Health, HHS)*COM019* Dated: September 10, 2012...

76 FR 28236 - National Institute on Aging; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-16

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... Emphasis Panel, Oxidative Stress and Aging. Date: July 13, 2011. Time: 12 p.m. to 4 p.m. Agenda: To review... Domestic Assistance Program Nos. 93.866, Aging Research, National Institutes of Health, HHS) Dated: May 10...

Improving Community Stroke Preparedness in the HHS (Hip-Hop Stroke) Randomized Clinical Trial.

PubMed

Williams, Olajide; Leighton-Herrmann Quinn, Ellyn; Teresi, Jeanne; Eimicke, Joseph P; Kong, Jian; Ogedegbe, Gbenga; Noble, James

2018-04-01

Deficiencies in stroke preparedness cause major delays to stroke thrombolysis, particularly among economically disadvantaged minorities. We evaluated the effectiveness of a stroke preparedness intervention delivered to preadolescent urban public school children on the stroke knowledge/preparedness of their parents. We recruited 3070 fourth through sixth graders and 1144 parents from 22 schools into a cluster randomized trial with schools randomized to the HHS (Hip-Hop Stroke) intervention or attentional control (nutrition classes). HHS is a 3-hour culturally tailored, theory-based, multimedia stroke literacy intervention targeting school children, which systematically empowers children to share stroke information with parents. Our main outcome measures were stroke knowledge/preparedness of children and parents using validated surrogates. Among children, it was estimated that 1% (95% confidence interval [CI], 0%-1%) of controls and 2% (95% CI, 1%-4%; P =0.09) of the intervention group demonstrated optimal stroke preparedness (perfect scores on the knowledge/preparedness test) at baseline, increasing to 57% (95% CI, 44%-69%) immediately after the program in the intervention group compared with 1% (95% CI, 0%-1%; P <0.001) among controls. At 3-month follow-up, 24% (95% CI, 15%-33%) of the intervention group retained optimal preparedness, compared with 2% (95% CI, 0%-3%; P <0.001) of controls. Only 3% (95% CI, 2%-4%) of parents in the intervention group could identify all 4 letters of the stroke FAST (Facial droop, Arm weakness, Speech disturbance, Time to call 911) acronym at baseline, increasing to 20% at immediate post-test (95% CI, 16%-24%) and 17% at 3-month delayed post-test (95% CI, 13%-21%; P =0.0062), with no significant changes (3% identification) among controls. Four children, all in the intervention group, called 911 for real-life stroke symptoms, in 1 case overruling a parent's wait-and-see approach. HHS is an effective, intergenerational model for

Does Causal Action Facilitate Causal Perception in Infants Younger than 6 Months of Age?

ERIC Educational Resources Information Center

Rakison, David H.; Krogh, Lauren

2012-01-01

Previous research has established that infants are unable to perceive causality until 6 1/4 months of age. The current experiments examined whether infants' ability to engage in causal action could facilitate causal perception prior to this age. In Experiment 1, 4 1/2-month-olds were randomly assigned to engage in causal action experience via…

48 CFR 311.7001 - Section 508 accessibility standards for HHS Web site content and communications materials.

Code of Federal Regulations, 2011 CFR

2011-10-01

... standards, and resolve any related issues. (c) Based on those discussions, the Project Officer shall provide... communication must meet the accessibility standards in 36 CFR 1194.22, “Web-based intranet and Internet... standards for HHS Web site content and communications materials. 311.7001 Section 311.7001 Federal...

48 CFR 311.7001 - Section 508 accessibility standards for HHS Web site content and communications materials.

Code of Federal Regulations, 2013 CFR

2013-10-01

... standards, and resolve any related issues. (c) Based on those discussions, the Project Officer shall provide... communication must meet the accessibility standards in 36 CFR 1194.22, “Web-based intranet and Internet... standards for HHS Web site content and communications materials. 311.7001 Section 311.7001 Federal...

48 CFR 311.7001 - Section 508 accessibility standards for HHS Web site content and communications materials.

Code of Federal Regulations, 2012 CFR

2012-10-01

... standards, and resolve any related issues. (c) Based on those discussions, the Project Officer shall provide... communication must meet the accessibility standards in 36 CFR 1194.22, “Web-based intranet and Internet... standards for HHS Web site content and communications materials. 311.7001 Section 311.7001 Federal...

48 CFR 311.7001 - Section 508 accessibility standards for HHS Web site content and communications materials.

Code of Federal Regulations, 2014 CFR

2014-10-01

... standards, and resolve any related issues. (c) Based on those discussions, the Project Officer shall provide... communication must meet the accessibility standards in 36 CFR 1194.22, “Web-based intranet and Internet... standards for HHS Web site content and communications materials. 311.7001 Section 311.7001 Federal...

45 CFR 91.4 - Definition of terms used in these regulations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM HHS... means the Age Discrimination Act of 1975, as amended, (Title III of Pub. L. 94-135). Action means any..., standard, or method of administration. Age means how old a person is, or the number of years from the date...

45 CFR 91.4 - Definition of terms used in these regulations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM HHS... means the Age Discrimination Act of 1975, as amended, (Title III of Pub. L. 94-135). Action means any..., standard, or method of administration. Age means how old a person is, or the number of years from the date...

45 CFR 91.4 - Definition of terms used in these regulations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM HHS... means the Age Discrimination Act of 1975, as amended, (Title III of Pub. L. 94-135). Action means any..., standard, or method of administration. Age means how old a person is, or the number of years from the date...

45 CFR 91.4 - Definition of terms used in these regulations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE FROM HHS... means the Age Discrimination Act of 1975, as amended, (Title III of Pub. L. 94-135). Action means any..., standard, or method of administration. Age means how old a person is, or the number of years from the date...

78 FR 23255 - Findings of Misconduct in Science/Research Misconduct

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-18

.../Research Misconduct AGENCY: Office of the Secretary, HHS. ACTION: Notice. SUMMARY: Notice is hereby given... Attorney for the District of Columbia in Bois v. HHS, et al., Civil Action no. 11-cv-1563, which was... proceedings regarding Finding 2. On March 30, 2012, HHS filed a Motion for Reconsideration before Judge Berman...

HHS guidance on synthetic DNA is the right step.

PubMed

Gronvall, Gigi Kwik

2010-12-01

Synthetic biology has advanced to the point where some pathogens can be manufactured from scratch. This technical leap has beneficent implications for medical research and vaccine design, but it also raises concerns that the technology could be used to produce a deadly pathogen for nefarious use. Addressing these concerns, the Department of Health and Human Services (HHS) released their Screening Framework Guidance for Providers of Synthetic Double-Stranded DNA on October 13, 2010. They took the right approach: The oversight framework for gene synthesis companies included in this guidance is adaptable to new technical developments and changing risks, it can be implemented immediately, it can be readily adopted by other countries, and it will cost little. Though there have been some calls to increase the regulatory controls on synthetic biology, these should be resisted. For now, at least, the oversight is appropriate to the risks.

78 FR 59696 - Agency Information Collection Activities; Proposed Collection; Public Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-27

...: Office of the Secretary, HHS. ACTION: Notice. SUMMARY: In compliance with section 3506(c)(2)(A) of the... of adults between the ages of 40 and 70 on long-term care awareness, how people plan for retirement... care programs, and individual homes. Most people with disabilities are elderly, but people of all ages...

42 CFR 55a.103 - What criteria has HHS established for deciding which grant application to fund?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false What criteria has HHS established for deciding which grant application to fund? 55a.103 Section 55a.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS PROGRAM GRANTS FOR BLACK LUNG CLINICS General Provisions § 55a...

42 CFR 55a.103 - What criteria has HHS established for deciding which grant application to fund?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false What criteria has HHS established for deciding which grant application to fund? 55a.103 Section 55a.103 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES GRANTS PROGRAM GRANTS FOR BLACK LUNG CLINICS General Provisions § 55a...

Mobility and Aging: New Directions for Public Health Action

PubMed Central

Guralnik, Jack M.; Jackson, Richard J.; Marottoli, Richard A.; Phelan, Elizabeth A.; Prohaska, Thomas R.

2012-01-01

Optimal mobility, defined as relative ease and freedom of movement in all of its forms, is central to healthy aging. Mobility is a significant consideration for research, practice, and policy in aging and public health. We examined the public health burdens of mobility disability, with a particular focus on leading public health interventions to enhance walking and driving, and the challenges and opportunities for public health action. We propose an integrated mobility agenda, which draws on the lived experience of older adults. New strategies for research, practice, and policy are needed to move beyond categorical promotion programs in walking and driving to establish a comprehensive program to enhance safe mobility in all its forms. PMID:22698013

Diabetes and Asians and Pacific Islanders

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Infant Mortality and Hispanic Americans

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Heart Disease and African Americans

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Infant Mortality and Asians and Pacific Islanders

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Immunizations and African Americans

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Diabetes and Hispanic Americans

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Diabetes and Native Hawaiians/Pacific Islanders

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Chronic Liver Disease and Asian Americans/Pacific Islanders

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Chronic Liver Disease and Native Hawaiian/Pacific Islanders

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Asthma and Native Hawaiians/Pacific Islanders

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Stroke and Native Hawaiians/Pacific Islanders

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Infant Mortality and Native Hawaiians/Pacific Islanders

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Asthma and American Indians/Alaska Natives

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Infant Mortality and American Indians/Alaska Natives

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Chronic Liver Disease and Hispanic Americans

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Cancer and Asians/Pacific Islanders

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Chronic Liver Disease and African Americans

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Infant Mortality and African Americans

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Cancer and African Americans

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Immunizations and Asians and Pacific Islanders

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

Heart Disease and Asians and Pacific Islanders

MedlinePlus

... Minority Health at HHS Advisory Committee Committees and Working Groups News HHS Disparities Action Plan National Partnership for Action Campaigns and Initiatives Performance Improvement and Management System Report to Congress Knowledge ...

77 FR 4044 - Agency Information Collection Activities; Proposed Collection; Comment Request; Annual Reporting...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-26

... Title VI Grant Program AGENCY: Administration on Aging, HHS. ACTION: Notice. SUMMARY: The Administration... information collection requirements relating to Performance Reports for Title VI grants. DATES: Submit written... Native Hawaiian Organizations receiving grants under Title VI, Part A, Grants for Native Americans; Title...

No privacy for all? Serious failings in the HHS medical records regulations.

PubMed

Sobel, Richard

2002-01-01

The Bush administration surprised many by the approval without major revisions of the Clinton administration's HHS medical records regulations, despite heavy lobbying from the health industry. Though these "privacy rules" are supposed to protect patient confidentiality, what has gone unmentioned are the regulations' major lapses that breach informed consent and confidentiality. Recently issued "clarifications" of the regulations reveal that they do not prevent unconsented access to sensitive medical information by marketers, health plans, health care clearinghouses, and law enforcement. These problems with the regulations constitute a serious breach of patient privacy, endangering the doctor-patient relationship and potentially driving up health care costs, and need to be addressed.

Anticipatory Action Planning Increases from 3 to 10 Years of Age in Typically Developing Children

ERIC Educational Resources Information Center

Jongbloed-Pereboom, Marjolein; Nijhuis-van der Sanden, Maria W. G.; Saraber-Schiphorst, Nicole; Craje, Celine; Steenbergen, Bert

2013-01-01

The primary aim of this study was to assess the development of action planning in a group of typically developing children aged 3 to 10 years (N = 351). The second aim was to assess reliability of the action planning task and to relate the results of the action planning task to results of validated upper limb motor performance tests. Participants…

77 FR 13337 - Agency Information Collection Activities; Proposed Collection; Comment Request; Annual Reporting...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-06

... Title VI Grant Program AGENCY: Administration on Aging, HHS. ACTION: Notice SUMMARY: The Administration... Native Hawaiian Organizations receiving grants under Title VI, Part A, Grants for Native Americans; Title VI, Part B, Native Hawaiian Program and Title VI, Part C, Native American Caregiver Support Program...

Aging and inhibitory control of action: cortico-subthalamic connection strength predicts stopping performance.

PubMed

Coxon, James P; Van Impe, Annouchka; Wenderoth, Nicole; Swinnen, Stephan P

2012-06-13

Diffusion weighted imaging (DWI) studies in humans have shown that seniors exhibit reduced white matter integrity compared with young adults, with the most pronounced change occurring in frontal white matter. It is generally assumed that this structural deterioration underlies inhibitory control deficits in old age, but specific evidence from a structural neuroscience perspective is lacking. Cognitive action control is thought to rely on an interconnected network consisting of right inferior frontal cortex (r-IFC), pre-supplementary motor area (preSMA), and the subthalamic nucleus (STN). Here we performed probabilistic DWI tractography to delineate this cognitive control network and had the same individuals (20 young, 20 older adults) perform a task probing both response inhibition and action reprogramming. We hypothesized that structural integrity (fractional anisotropy) and connection strength within this network would be predictive of individual and age-related differences in task performance. We show that the integrity of r-IFC white matter is an age-independent predictor of stop-signal reaction time (SSRT). We further provide evidence that the integrity of white matter projecting to STN predicts both outright stopping (SSRT) and transient braking of response initiation to buy time for action reprogramming (stopping interference effects). These associations remain even after controlling for Go task performance, demonstrating specificity to the Stop component of this task. Finally, a multiple regression analysis reveals bilateral preSMA-STN tract strength as a significant predictor of SSRT in older adults. Our data link age-related decline in inhibitory control with structural decline of STN projections.

Is there an advanced aging effect on the ability to mentally represent action?

PubMed

Gabbard, Carl; Caçola, Priscila; Cordova, Alberto

2011-01-01

Motor programming theory suggests that an integral component in an effective outcome is an adequate action (mental) representation of the movements; a representation reflected in the ability to use motor imagery. Recent reports show a decline with advanced age (>64 years) using a variety of motor simulation tasks. Here, we examined the possible effects of advanced age on motor imagery ability in the context of estimation of reachability--that is, estimating whether an object is within reach or out of grasp. Thirty young adults (mean age: 20) and 23 older adults (mean age: 77) were instructed to estimate, using motor imagery, whether randomly presented targets in peripersonal (within actual reach) and extrapersonal (beyond reach) space were within or out of reach of their dominant limb while seated. Results indicated that the younger group was significantly more accurate than the older adults, p < 0.001. Whereas both groups made more errors in extrapersonal space, the values were significantly higher for the older group; that is, they overestimated to a greater extent. In summary, these findings add to the general notion that there is a decline in the ability to mentally represent action with advanced age. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

Nondiscrimination on the basis of handicap relating to health care for handicapped infants--Office of the Secretary, HHS. Proposed rules.

PubMed

1983-07-05

The notice of proposed rulemaking proposes to modify existing regulations to meet the exigent needs that can arise when a handicapped infant is discriminatorily denied food or medically indicated treatment. Several current regulatory provisions are proposed to be modified to allow timely reporting of violations, expeditious investigation, and immediate enforcement action when necessary to protect a handicapped infant whose life is endangered by discrimination in a program or activity receiving federal financial assistance. Recipients that provide health care to infants would be required to post a conspicuous notice in locations that provide such care. The notice would describe the protections under federal law against discrimination toward the handicapped, and would provide a contact point in the Department of HHS for reporting violations immediately by telephone. Notice and complaint procedures have been effective instruments for deterrence and enforcement in a variety of civil rights contexts. The Secretary believes that the proposed rule provides the best means to ensure that violations can be reported in time to save the lives of handicapped infants who are denied food or are otherwise imperiled by discrimination in the provision of health care by federally assisted programs or activities.

42 CFR 93.407 - HHS administrative actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON... cooperative agreement. (6) Special review of all requests for PHS funding. (7) Imposition of supervision... PHS funding component, and the debarring official. ...

76 FR 21902 - Privacy Act of 1974; Report of a New System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-19

... HHS contracting officers, vendor names, mailing addresses, phone numbers, financial account... Financial Resources (ASFR), Department of Health and Human Services (HHS). ACTION: Notice of New System of... all interfaces to financial, inventory, and other systems that HHS has or will employ. HCAS replaced...

42 CFR 1007.20 - Circumstances in which data mining is permissible and approval by HHS Office of Inspector General.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 42 Public Health 5 2013-10-01 2013-10-01 false Circumstances in which data mining is permissible... CONTROL UNITS § 1007.20 Circumstances in which data mining is permissible and approval by HHS Office of Inspector General. (a) Notwithstanding § 1007.19(e)(2), a MFCU may engage in data mining as defined in this...

42 CFR 1007.20 - Circumstances in which data mining is permissible and approval by HHS Office of Inspector General.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 42 Public Health 5 2014-10-01 2014-10-01 false Circumstances in which data mining is permissible... CONTROL UNITS § 1007.20 Circumstances in which data mining is permissible and approval by HHS Office of Inspector General. (a) Notwithstanding § 1007.19(e)(2), a MFCU may engage in data mining as defined in this...

75 FR 30839 - Privacy Act of 1974; CMS Computer Match No. 2010-03, HHS Computer Match No. 1003, SSA Computer...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-02

... of the Matching Program A. General The Computer Matching and Privacy Protection Act of 1988 (Pub. L.... 100-503, the Computer Matching and Privacy Protection Act (CMPPA) of 1988), the Office of Management... 1974; CMS Computer Match No. 2010-03, HHS Computer Match No. 1003, SSA Computer Match No. 1048, IRS...

41 CFR 102-75.495 - May the Department of Education (ED) or the Department of Health and Human Services (HHS) notify...

Code of Federal Regulations, 2014 CFR

2014-01-01

... surplus real property and related personal property is available for educational and public health... DISPOSAL Surplus Real Property Disposal Property for Educational and Public Health Purposes § 102-75.495... educational and public health purposes? Yes, ED or HHS may notify eligible non-profit institutions that such...

41 CFR 102-75.495 - May the Department of Education (ED) or the Department of Health and Human Services (HHS) notify...

Code of Federal Regulations, 2013 CFR

2013-07-01

... surplus real property and related personal property is available for educational and public health... DISPOSAL Surplus Real Property Disposal Property for Educational and Public Health Purposes § 102-75.495... educational and public health purposes? Yes, ED or HHS may notify eligible non-profit institutions that such...

41 CFR 102-75.495 - May the Department of Education (ED) or the Department of Health and Human Services (HHS) notify...

Code of Federal Regulations, 2012 CFR

2012-01-01

... surplus real property and related personal property is available for educational and public health... DISPOSAL Surplus Real Property Disposal Property for Educational and Public Health Purposes § 102-75.495... educational and public health purposes? Yes, ED or HHS may notify eligible non-profit institutions that such...

41 CFR 102-75.495 - May the Department of Education (ED) or the Department of Health and Human Services (HHS) notify...

Code of Federal Regulations, 2011 CFR

2011-01-01

... surplus real property and related personal property is available for educational and public health... DISPOSAL Surplus Real Property Disposal Property for Educational and Public Health Purposes § 102-75.495... educational and public health purposes? Yes, ED or HHS may notify eligible non-profit institutions that such...

41 CFR 102-75.495 - May the Department of Education (ED) or the Department of Health and Human Services (HHS) notify...

Code of Federal Regulations, 2010 CFR

2010-07-01

... surplus real property and related personal property is available for educational and public health... DISPOSAL Surplus Real Property Disposal Property for Educational and Public Health Purposes § 102-75.495... educational and public health purposes? Yes, ED or HHS may notify eligible non-profit institutions that such...

42 CFR 93.516 - Standard and burden of proof.

Code of Federal Regulations, 2010 CFR

2010-10-01

... that are relevant to a decision to impose HHS administrative actions following a research misconduct... RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.516 Standard and burden of proof. (a) Standard of proof. The standard of...

42 CFR 93.516 - Standard and burden of proof.

Code of Federal Regulations, 2011 CFR

2011-10-01

... that are relevant to a decision to impose HHS administrative actions following a research misconduct... RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.516 Standard and burden of proof. (a) Standard of proof. The standard of...

77 FR 15759 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-16

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort AGENCY: National Institute for Occupational Safety and Health... Services (HHS). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of the HHS decision...

The functional organization of preschool-age children's emotion expressions and actions in challenging situations.

PubMed

Dennis, Tracy A; Cole, Pamela M; Wiggins, Crystal N; Cohen, Laura H; Zalewski, Maureen

2009-08-01

Although functional links between emotion and action are implied in emotion regulation research, there is limited evidence that specific adaptive actions for coping with a challenge are more probable when certain negative emotions are expressed. The current study examined this question among 3- and 4-year-olds (N = 113; M age = 47.84 months, SD = 6.19). Emotion expressions and actions were observed during 2 challenging tasks: children waited for a gift while the mother worked, and children worked alone to retrieve a prize from a locked box with the wrong key. Angry and happy expressions, compared with sad expressions, were associated with more actions. These actions varied with the nature of the task, reflecting appreciation of situational appropriateness. In addition, when waiting with the mother, happiness was associated with the broadest range of actions, whereas when working alone on the locked box, anger was associated with the broadest range of actions. Results are discussed in terms of the adaptive function of negative emotions and in terms of functional and dimensional models of emotion. Findings have implications for the development of emotion regulation and social-emotional competence. 2009 APA, all rights reserved.

What drives young children to over-imitate? Investigating the effects of age, context, action type, and transitivity.

PubMed

Clay, Zanna; Over, Harriet; Tennie, Claudio

2018-02-01

Imitation underlies many traits thought to characterize our species, which includes the transmission and acquisition of language, material culture, norms, rituals, and conventions. From early childhood, humans show an intriguing willingness to imitate behaviors, even those that have no obvious function. This phenomenon, known as "over-imitation," is thought to explain some of the key differences between human cultures as compared with those of nonhuman animals. Here, we used a single integrative paradigm to simultaneously investigate several key factors proposed to shape children's over-imitation: age, context, transitivity, and action type. We compared typically developing children aged 4-6years in a task involving actions verbally framed as being instrumental, normative, or communicative in function. Within these contexts, we explored whether children were more likely to over-imitate transitive versus intransitive actions and manual versus body part actions. Results showed an interaction between age and context; as children got older, they were more likely to imitate within a normative context, whereas younger children were more likely to imitate in instrumental contexts. Younger children were more likely to imitate transitive actions (actions on objects) than intransitive actions compared with older children. Our results show that children are highly sensitive to even minimal cues to perceived context and flexibly adapt their imitation accordingly. As they get older, children's imitation appears to become less object bound, less focused on instrumental outcomes, and more sensitive to normative cues. This shift is consistent with the proposal that over-imitation becomes increasingly social in its function as children move through childhood and beyond. Copyright © 2017 Elsevier Inc. All rights reserved.

42 CFR 93.523 - The Administrative Law Judge's ruling.

Code of Federal Regulations, 2010 CFR

2010-10-01

... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.523 The Administrative Law Judge's ruling. (a) The ALJ shall issue a... decision in whole or in part is the final HHS action, unless debarment or suspension is an administrative...

42 CFR 93.523 - The Administrative Law Judge's ruling.

Code of Federal Regulations, 2011 CFR

2011-10-01

... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.523 The Administrative Law Judge's ruling. (a) The ALJ shall issue a... decision in whole or in part is the final HHS action, unless debarment or suspension is an administrative...

Review of nutrient actions on age-related macular degeneration.

PubMed

Zampatti, Stefania; Ricci, Federico; Cusumano, Andrea; Marsella, Luigi Tonino; Novelli, Giuseppe; Giardina, Emiliano

2014-02-01

The actions of nutrients and related compounds on age-related macular degeneration (AMD) are explained in this review. The findings from 80 studies published since 2003 on the association between diet and supplements in AMD were reviewed. Antioxidants and other nutrients with an effect on AMD susceptibility include carotenoids (lutein and zeaxanthin, β-carotene), vitamins (vitamin A, E, C, D, B), mineral supplements (zinc, copper, selenium), dietary fatty acids [monounsaturated fatty acids, polyunsaturated fatty acids (PUFA both omega-3 PUFA and omega-6 PUFA), saturated fatty acids and cholesterol], and dietary carbohydrates. The literature revealed that many of these antioxidants and nutrients exert a protective role by functioning synergistically. Specifically, the use of dietary supplements with targeted actions can provide minimal benefits on the onset or progression of AMD; however, this does not appear to be particularly beneficial in healthy people. Furthermore, some supplements or nutrients have demonstrated discordant effects on AMD in some studies. Since intake of dietary supplements, as well as exposure to damaging environmental factors, is largely dependent on population habits (including dietary practices) and geographical localization, an overall healthy diet appears to be the best strategy in reducing the risk of developing AMD. As of now, the precise mechanism of action of certain nutrients in AMD prevention remains unclear. Thus, future studies are required to examine the effects that nutrients have on AMD and to determine which factors are most strongly correlated with reducing the risk of AMD or preventing its progression. Copyright © 2014 Elsevier Inc. All rights reserved.

Ten commandments for the future of ageing research in the UK: a vision for action

PubMed Central

Franco, Oscar H; Kirkwood, Thomas BL; Powell, Jonathan R; Catt, Michael; Goodwin, James; Ordovas, Jose M; van der Ouderaa, Frans

2007-01-01

Increases in longevity resulting from improvements in health care and living conditions together with a decrease in fertility rates have contributed to a shift towards an aged population profile. For the first time the UK has more people over age 60 than below 16 years of age. The increase in longevity has not been accompanied by an increase in disease-free life expectancy and research into ageing is required to improve the health and quality of life of older people. However, as the House of Lords reported, ageing research in the UK is not adequately structured and a clear vision and plan are urgently required. Hence, with the aim of setting a common vision for action in ageing research in the UK, a 'Spark Workshop' was organised. International experts from different disciplines related to ageing research gathered to share their perspectives and to evaluate the present status of ageing research in the UK. A detailed assessment of potential improvements was conducted and the prospective secondary gains were considered, which were subsequently distilled into a list of 'ten commandments'. We believe that these commandments, if followed, will help to bring about the necessary implementation of an action plan for ageing research in the UK, commensurate with the scale of the challenge, which is to transform the manifold opportunities of increased longevity into actual delivery of a society living not only for longer, but also healthier, wealthier and happier. PMID:17477869

The bare essentials. Release of LOM report leaves HHS to determine what should be covered by health benefits packages.

PubMed

Zigmond, Jessica

2011-10-10

In the wake of an IOM report on the criteria HHS should use to determine what benefits will be "essential" under reform, various stakeholders are weighing in. The National Association of Public Hospitals and Health Systems would like "enabling" services--such as language, transportation and case-management services--included, because they help make medical care more effective, says Xiaoyi Huang, left, of the NAPH.

Heat and moisture exchangers (HMEs) and heated humidifiers (HHs) in adult critically ill patients: a systematic review, meta-analysis and meta-regression of randomized controlled trials.

PubMed

Vargas, Maria; Chiumello, Davide; Sutherasan, Yuda; Ball, Lorenzo; Esquinas, Antonio M; Pelosi, Paolo; Servillo, Giuseppe

2017-05-29

The aims of this systematic review and meta-analysis of randomized controlled trials are to evaluate the effects of active heated humidifiers (HHs) and moisture exchangers (HMEs) in preventing artificial airway occlusion and pneumonia, and on mortality in adult critically ill patients. In addition, we planned to perform a meta-regression analysis to evaluate the relationship between the incidence of artificial airway occlusion, pneumonia and mortality and clinical features of adult critically ill patients. Computerized databases were searched for randomized controlled trials (RCTs) comparing HHs and HMEs and reporting artificial airway occlusion, pneumonia and mortality as predefined outcomes. Relative risk (RR), 95% confidence interval for each outcome and I 2 were estimated for each outcome. Furthermore, weighted random-effect meta-regression analysis was performed to test the relationship between the effect size on each considered outcome and covariates. Eighteen RCTs and 2442 adult critically ill patients were included in the analysis. The incidence of artificial airway occlusion (RR = 1.853; 95% CI 0.792-4.338), pneumonia (RR = 932; 95% CI 0.730-1.190) and mortality (RR = 1.023; 95% CI 0.878-1.192) were not different in patients treated with HMEs and HHs. However, in the subgroup analyses the incidence of airway occlusion was higher in HMEs compared with HHs with non-heated wire (RR = 3.776; 95% CI 1.560-9.143). According to the meta-regression, the effect size in the treatment group on artificial airway occlusion was influenced by the percentage of patients with pneumonia (β = -0.058; p = 0.027; favors HMEs in studies with high prevalence of pneumonia), and a trend was observed for an effect of the duration of mechanical ventilation (MV) (β = -0.108; p = 0.054; favors HMEs in studies with longer MV time). In this meta-analysis we found no superiority of HMEs and HHs, in terms of artificial airway occlusion, pneumonia and

78 FR 9927 - Agency Information Collection Activities; Proposed Collection; Comment Request; State Program Report

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-12

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Action Prediction Allows Hypothesis Testing via Internal Forward Models at 6 Months of Age

PubMed Central

Gredebäck, Gustaf; Lindskog, Marcus; Juvrud, Joshua C.; Green, Dorota; Marciszko, Carin

2018-01-01

We propose that action prediction provides a cornerstone in a learning process known as internal forward models. According to this suggestion infants’ predictions (looking to the mouth of someone moving a spoon upward) will moments later be validated or proven false (spoon was in fact directed toward a bowl), information that is directly perceived as the distance between the predicted and actual goal. Using an individual difference approach we demonstrate that action prediction correlates with the tendency to react with surprise when social interactions are not acted out as expected (action evaluation). This association is demonstrated across tasks and in a large sample (n = 118) at 6 months of age. These results provide the first indication that infants might rely on internal forward models to structure their social world. Additional analysis, consistent with prior work and assumptions from embodied cognition, demonstrates that the latency of infants’ action predictions correlate with the infant’s own manual proficiency. PMID:29593600

The Functional Organization of Preschool-Age Children’s Emotion Expressions and Actions in Challenging Situations

PubMed Central

Dennis, Tracy A.; Cole, Pamela M.; Wiggins, Crystal N.; Cohen, Laura H.; Zalewski, Maureen

2010-01-01

Although functional links between emotion and action are implied in emotion regulation research, there is limited evidence that specific adaptive actions for coping with a challenge are more probable when certain negative emotions are expressed. The current study examined this question among 3- and 4-year-olds (N = 113; M age = 47.84 months, SD = 6.19). Emotion expressions and actions were observed during 2 challenging tasks: children waited for a gift while the mother worked, and children worked alone to retrieve a prize from a locked box with the wrong key. Angry and happy expressions, compared with sad expressions, were associated with more actions. These actions varied with the nature of the task, reflecting appreciation of situational appropriateness. In addition, when waiting with the mother, happiness was associated with the broadest range of actions, whereas when working alone on the locked box, anger was associated with the broadest range of actions. Results are discussed in terms of the adaptive function of negative emotions and in terms of functional and dimensional models of emotion. Findings have implications for the development of emotion regulation and social–emotional competence. PMID:19653775

Effects of age and muscle action type on acute strength and power recovery following fatigue of the leg flexors.

PubMed

Thompson, Brennan J; Conchola, Eric C; Stock, Matt S

2015-12-01

Short-term strength and power recovery patterns following fatigue have received little research attention, particularly as they pertain to age-specific responses, and the leg flexors (i.e., hamstrings) muscle group. Thus, research is warranted addressing these issues because both age-related alterations in the neuromuscular system and mode of muscle action (e.g., eccentric, concentric, isometric) may differentially influence recovery responses from fatigue. The aim of this study was to investigate the strength and power recovery responses for eccentric, concentric, and isometric muscle actions of the leg flexors in young and older men following an isometric, intermittent fatigue-inducing protocol. Nineteen young (age = 25 ± 3 years) and nineteen older (71 ± 4) men performed maximal voluntary contractions (MVCs) for eccentric, concentric, and isometric muscle actions followed by a fatigue protocol of intermittent (0.6 duty cycle) isometric contractions of the leg flexors at 60% of isometric MVC. MVCs of each muscle action were performed at 0, 7, 15, and 30 min following fatigue. Peak torque (PT) and mean power values were calculated from the MVCs and the eccentric/concentric ratio (ECR) was derived. For PT and mean power, young men showed incomplete recovery at all time phases, whereas the older men had recovered by 7 min. Eccentric and isometric muscle actions showed incomplete recovery at all time phases, but concentric recovered by 7 min, independent of age. The ECR was depressed for up to 30 min following fatigue. More rapid and pronounced recovery in older men and concentric contractions may be related to physiological differences specific to aging and muscle action motor unit patterns. Individuals and clinicians may use these time course responses as a guide for recovery following activity-induced fatigue.

Building Bridges for Innovation in Ageing: Synergies between Action Groups of the EIP on AHA.

PubMed

Bousquet, J; Bewick, M; Cano, A; Eklund, P; Fico, G; Goswami, N; Guldemond, N A; Henderson, D; Hinkema, M J; Liotta, G; Mair, A; Molloy, W; Monaco, A; Monsonis-Paya, I; Nizinska, A; Papadopoulos, H; Pavlickova, A; Pecorelli, S; Prados-Torres, A; Roller-Wirnsberger, R E; Somekh, D; Vera-Muñoz, C; Visser, F; Farrell, J; Malva, J; Andersen Ranberg, K; Camuzat, T; Carriazo, A M; Crooks, G; Gutter, Z; Iaccarino, G; Manuel de Keenoy, E; Moda, G; Rodriguez-Mañas, L; Vontetsianos, T; Abreu, C; Alonso, J; Alonso-Bouzon, C; Ankri, J; Arredondo, M T; Avolio, F; Bedbrook, A; Białoszewski, A Z; Blain, H; Bourret, R; Cabrera-Umpierrez, M F; Catala, A; O'Caoimh, R; Cesari, M; Chavannes, N H; Correia-da-Sousa, J; Dedeu, T; Ferrando, M; Ferri, M; Fokkens, W J; Garcia-Lizana, F; Guérin, O; Hellings, P W; Haahtela, T; Illario, M; Inzerilli, M C; Lodrup Carlsen, K C; Kardas, P; Keil, T; Maggio, M; Mendez-Zorrilla, A; Menditto, E; Mercier, J; Michel, J P; Murray, R; Nogues, M; O'Byrne-Maguire, I; Pappa, D; Parent, A S; Pastorino, M; Robalo-Cordeiro, C; Samolinski, B; Siciliano, P; Teixeira, A M; Tsartara, S I; Valiulis, A; Vandenplas, O; Vasankari, T; Vellas, B; Vollenbroek-Hutten, M; Wickman, M; Yorgancioglu, A; Zuberbier, T; Barbagallo, M; Canonica, G W; Klimek, L; Maggi, S; Aberer, W; Akdis, C; Adcock, I M; Agache, I; Albera, C; Alonso-Trujillo, F; Angel Guarcia, M; Annesi-Maesano, I; Apostolo, J; Arshad, S H; Attalin, V; Avignon, A; Bachert, C; Baroni, I; Bel, E; Benson, M; Bescos, C; Blasi, F; Barbara, C; Bergmann, K C; Bernard, P L; Bonini, S; Bousquet, P J; Branchini, B; Brightling, C E; Bruguière, V; Bunu, C; Bush, A; Caimmi, D P; Calderon, M A; Canovas, G; Cardona, V; Carlsen, K H; Cesario, A; Chkhartishvili, E; Chiron, R; Chivato, T; Chung, K F; d'Angelantonio, M; De Carlo, G; Cholley, D; Chorin, F; Combe, B; Compas, B; Costa, D J; Costa, E; Coste, O; Coupet, A-L; Crepaldi, G; Custovic, A; Dahl, R; Dahlen, S E; Demoly, P; Devillier, P; Didier, A; Dinh-Xuan, A T; Djukanovic, R; Dokic, D; Du Toit, G; Dubakiene, R; Dupeyron, A; Emuzyte, R; Fiocchi, A; Wagner, A; Fletcher, M; Fonseca, J; Fougère, B; Gamkrelidze, A; Garces, G; Garcia-Aymeric, J; Garcia-Zapirain, B; Gemicioğlu, B; Gouder, C; Hellquist-Dahl, B; Hermosilla-Gimeno, I; Héve, D; Holland, C; Humbert, M; Hyland, M; Johnston, S L; Just, J; Jutel, M; Kaidashev, I P; Khaitov, M; Kalayci, O; Kalyoncu, A F; Keijser, W; Kerstjens, H; Knezović, J; Kowalski, M; Koppelman, G H; Kotska, T; Kovac, M; Kull, I; Kuna, P; Kvedariene, V; Lepore, V; MacNee, W; Maggio, M; Magnan, A; Majer, I; Manning, P; Marcucci, M; Marti, T; Masoli, M; Melen, E; Miculinic, N; Mihaltan, F; Milenkovic, B; Millot-Keurinck, J; Mlinarić, H; Momas, I; Montefort, S; Morais-Almeida, M; Moreno-Casbas, T; Mösges, R; Mullol, J; Nadif, R; Nalin, M; Navarro-Pardo, E; Nekam, K; Ninot, G; Paccard, D; Pais, S; Palummeri, E; Panzner, P; Papadopoulos, N K; Papanikolaou, C; Passalacqua, G; Pastor, E; Perrot, M; Plavec, D; Popov, T A; Postma, D S; Price, D; Raffort, N; Reuzeau, J C; Robine, J M; Rodenas, F; Robusto, F; Roche, N; Romano, A; Romano, V; Rosado-Pinto, J; Roubille, F; Ruiz, F; Ryan, D; Salcedo, T; Schmid-Grendelmeier, P; Schulz, H; Schunemann, H J; Serrano, E; Sheikh, A; Shields, M; Siafakas, N; Scichilone, N; Siciliano, P; Skrindo, I; Smit, H A; Sourdet, S; Sousa-Costa, E; Spranger, O; Sooronbaev, T; Sruk, V; Sterk, P J; Todo-Bom, A; Touchon, J; Tramontano, D; Triggiani, M; Tsartara, S I; Valero, A L; Valovirta, E; van Ganse, E; van Hage, M; van den Berge, M; Vandenplas, O; Ventura, M T; Vergara, I; Vezzani, G; Vidal, D; Viegi, G; Wagemann, M; Whalley, B; Wickman, M; Wilson, N; Yiallouros, P K; Žagar, M; Zaidi, A; Zidarn, M; Hoogerwerf, E J; Usero, J; Zuffada, R; Senn, A; de Oliveira-Alves, B

2017-01-01

The Strategic Implementation Plan of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) proposed six Action Groups. After almost three years of activity, many achievements have been obtained through commitments or collaborative work of the Action Groups. However, they have often worked in silos and, consequently, synergies between Action Groups have been proposed to strengthen the triple win of the EIP on AHA. The paper presents the methodology and current status of the Task Force on EIP on AHA synergies. Synergies are in line with the Action Groups' new Renovated Action Plan (2016-2018) to ensure that their future objectives are coherent and fully connected. The outcomes and impact of synergies are using the Monitoring and Assessment Framework for the EIP on AHA (MAFEIP). Eight proposals for synergies have been approved by the Task Force: Five cross-cutting synergies which can be used for all current and future synergies as they consider overarching domains (appropriate polypharmacy, citizen empowerment, teaching and coaching on AHA, deployment of synergies to EU regions, Responsible Research and Innovation), and three cross-cutting synergies focussing on current Action Group activities (falls, frailty, integrated care and chronic respiratory diseases).

76 FR 59144 - National Practitioner Data Bank; Name Change of Proactive Disclosure Service (PDS) to Continuous...

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2011-09-23

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78 FR 41412 - Notice of Availability of Policy Document

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2013-07-10

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Central insulin-like growth factor-1 (IGF-1) restores whole-body insulin action in a model of age-related insulin resistance and IGF-1 decline.

PubMed

Huffman, Derek M; Farias Quipildor, Gabriela; Mao, Kai; Zhang, Xueying; Wan, Junxiang; Apontes, Pasha; Cohen, Pinchas; Barzilai, Nir

2016-02-01

Low insulin-like growth factor-1 (IGF-1) signaling is associated with improved longevity, but is paradoxically linked with several age-related diseases in humans. Insulin-like growth factor-1 has proven to be particularly beneficial to the brain, where it confers protection against features of neuronal and cognitive decline. While aging is characterized by central insulin resistance in the face of hyperinsulinemia, the somatotropic axis markedly declines in older humans. Thus, we hypothesized that increasing IGF-1 in the brain may prove to be a novel therapeutic alternative to overcome central insulin resistance and restore whole-body insulin action in aging. Utilizing hyperinsulinemic-euglycemic clamps, we show that old insulin-resistant rats with age-related declines in IGF-1 level demonstrate markedly improved whole-body insulin action, when treated with central IGF-1, as compared to central vehicle or insulin (P < 0.05). Furthermore, central IGF-1, but not insulin, suppressed hepatic glucose production and increased glucose disposal rates in aging rats (P < 0.05). Taken together, IGF-1 action in the brain and periphery provides a 'balance' between its beneficial and detrimental actions. Therefore, we propose that strategies aimed at 'tipping the balance' of IGF-1 action centrally are the optimal approach to achieve healthy aging and longevity in humans. © 2015 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

Modalities of gene action predicted by the classical evolutionary biological theory of aging.

PubMed

Martin, George M

2007-04-01

What might now be referred to as the "classical" evolutionary biological theory of why we age has had a number of serious challenges in recent years. While the theory might therefore have to be modified under certain circumstances, in the author's opinion, it still provides the soundest theoretical basis for thinking about how we age. Nine modalities of gene action that have the potential to modulate processes of aging are reviewed, including the two most widely reviewed and accepted concepts ("antagonistic pleiotropy" and "mutation accumulation"). While several of these nine mechanisms can be regarded as derivatives of the antagonistic pleiotropic concept, they frame more specific questions for future research. Such research should pursue what appears to be the dominant factor in the determination of intraspecific variations in longevity-stochastic mechanisms, most likely based upon epigenetics. This contrasts with the dominant factor in the determination of interspecific variations in longevity-the constitutional genome, most likely based upon variations in regulatory loci.

[European innovation partnership on active and healthy aging: moving from policy to action].

PubMed

García Lizana, Francisca

2013-01-01

Demographic change and aging are a common challenge in Europe. The rising number of elderly people will need support at home, and will consume more healthcare services, putting further pressure on the welfare system. Collaborative, integrated and people-centered care provision, whether in hospitals, homes or in the community, is a way forward to sustainable and efficient care systems. Innovative treatments to address chronic diseases and the functional decline of older people will enable them to live longer in better health and with a better quality of life. To fully unleash the potential of aging in the European Union, the European Commission -within its Innovation Union policy- launched the first European Innovation Partnership on Active and Healthy Ageing (EIP AHA). Promoting engagement and partnerships among all stakeholders in the healthcare chain is essential. This article describes the theoretical foundations, the development and expectations of the initiative, and its first actions. Copyright © 2012 SESPAS. Published by Elsevier Espana. All rights reserved.

76 FR 72325 - Privacy Act; Exempt Record System

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2011-10-01

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77 FR 15759 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

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2013-09-18

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Femoral neck shortening in adult patients under the age of 55 years is associated with worse functional outcomes: Analysis of the prospective multi-center study of hip fracture outcomes in China (SHOC).

PubMed

Slobogean, Gerard P; Stockton, David J; Zeng, Bing-Fang; Wang, Dong; Ma, Baotong; Pollak, Andrew N

2017-08-01

Young femoral neck fracture patients require surgical fixation to preserve the native hip joint and accommodate increased functional demands. Recent reports have identified a high incidence of fracture shortening and this may have negative functional consequences. We sought to determine if fracture shortening is associated with poor functional outcome in young femoral neck fracture patients. One hundred and forty-two patients with femoral neck fractures age 18-55 were recruited in this prospective cohort study across three Level 1 trauma hospitals in Mainland China. Patient-reported and objective functional outcomes were measured with the Harris Hip Score (HHS), Timed Up and Go (TUG), and SF-36 Physical Component Summary (SF-36 PCS) at 12 months. Radiographic fracture shortening was measured along the long axis of the femoral neck and corrected for magnification. Severe shortening was defined as ≥10mm. The primary analysis measured associations between severe radiographic shortening and HHS at one-year post-fixation. One hundred and two patients had complete radiographic and functional outcomes available for analysis at one year. The mean age of participants was 43.7±10.8years and 53% were male. Fifty-five percent of fractures were displaced and 37% were vertically orientated (Pauwels Type 3). The mean functional outcome scores were: HHS 90.0±10.8, TUG 12.0±5.1s, and PCS 48.5±8.6. Severe shortening occurred in 13% of patients and was associated with worse functional outcome scores: HHS mean difference 9.9 (p=0.025), TUG mean difference 3.2s (p=0.082), and PCS mean difference 5.4 (p=0.055). Severe shortening is associated with clinically important decreases in functional outcome as measured by HHS following fixation of young femoral neck fractures, occurring in 13% of patients in this population. The principle of fracture site compression utilized by modern constructs may promote healing; however, excessive shortening is associated with worse patient

Impaired awareness of action-outcome contingency and causality during healthy ageing and following ventromedial prefrontal cortex lesions.

PubMed

O'Callaghan, Claire; Vaghi, Matilde M; Brummerloh, Berit; Cardinal, Rudolf N; Robbins, Trevor W

2018-02-02

Detecting causal relationships between actions and their outcomes is fundamental to guiding goal-directed behaviour. The ventromedial prefrontal cortex (vmPFC) has been extensively implicated in computing these environmental contingencies, via animal lesion models and human neuroimaging. However, whether the vmPFC is critical for contingency learning, and whether it can occur without subjective awareness of those contingencies, has not been established. To address this, we measured response adaption to contingency and subjective awareness of action-outcome relationships in individuals with vmPFC lesions and healthy elderly subjects. We showed that in both vmPFC damage and ageing, successful behavioural adaptation to variations in action-outcome contingencies was maintained, but subjective awareness of these contingencies was reduced. These results highlight two contexts where performance and awareness have been dissociated, and show that learning response-outcome contingencies to guide behaviour can occur without subjective awareness. Preserved responding in the vmPFC group suggests that this region is not critical for computing action-outcome contingencies to guide behaviour. In contrast, our findings highlight a critical role for the vmPFC in supporting awareness, or metacognitive ability, during learning. We further advance the hypothesis that responding to changing environmental contingencies, whilst simultaneously maintaining conscious awareness of those statistical regularities, is a form of dual-tasking that is impaired in ageing due to reduced prefrontal function. Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

78 FR 77686 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

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2013-12-24

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77 FR 76489 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-28

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Designation of a Class of Employees for Addition to the... Disease Control and Prevention, Department of Health and Human Services (HHS). ACTION: Notice. SUMMARY: HHS gives notice of a decision to designate a class of employees from the Mound Plant in Miamisburg...

76 FR 63891 - Foreign Quarantine; Etiological Agents, Hosts, and Vectors

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-14

... DEPARTMENT OF HEALTH AND HUMAN SERVICES 42 CFR Part 71 [Docket No. CDC-2011-0007] RIN 0920-AA37... Prevention (CDC), Department of Health and Human Services (HHS). ACTION: Notice of proposed rulemaking... Human Services (HHS) is issuing this Notice of Proposed Rulemaking (NPRM) to revise the regulations that...

78 FR 12937 - Additional Safeguards for Children in Clinical Investigations of Food and Drug Administration...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-26

... Act requires that all research involving children that is conducted, supported, or regulated by the... protections for children involved as subjects in research. FDA is taking this action both to comply with the... research involving children conducted, supported, or regulated by HHS be in compliance with HHS regulations...

76 FR 33763 - Findings of Misconduct in Science/Research Misconduct

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-09

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the Secretary Findings of Misconduct in Science/Research Misconduct AGENCY: Office of the Secretary, HHS. ACTION: Notice. SUMMARY: Notice is hereby given... of the Secretary of HHS, issued a final notice of debarment based on the misconduct in science and...

76 FR 37119 - Development of Best Practices for Community Health Needs Assessment and Implementation Strategy...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-24

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Development of...: Centers for Disease Control and Prevention (CDC), Department of Health and Human Services (HHS). ACTION... the Department of Health and Human Services (HHS), will hold a public forum from July 11-13, 2011 on...

75 FR 32490 - Issues in the Development of Medical Products for the Prophylaxis and/or Treatment of Acute...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-08

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0001..., HHS. ACTION: Notice of public workshop. SUMMARY: The Food and Drug Administration (FDA) is announcing... name, address, telephone, and fax number) to [email protected]fda.hhs.gov . Persons without access to the...

Privacy Act of 1974; altered system of records--PHS. Notification of altered system of records: 09-30-0036, "Alcohol, Drug Abuse, and Mental Health Epidemiologic and Biometric Research Data, HHS/ADAMHA/OA".

PubMed

1984-10-23

In accordance with the requirements of the Privacy Act, the Public Health Service (OHS) is publishing a notice of proposal to alter the system of records in the Alcohol, Drug Abuse, and Mental Health Administration (ADAMHA), National Institute of Mental Health (NIMH), entitled, "Mental Health Epidemiologic and Biometric Research Data, HHS/ADAMHA/NIMH," to create an umbrella system of records to include epidemiologic and biometric research data in the areas of alcohol and drug abuse in addition to data already collected and maintained for mental health research. The system is to be retitled, "Alcohol, Drug Abuse, and Mental Health Epidemiologic and Biometric Research Data, HHS/ADAMHA/OA." PHS invites interested persons to submit comments on the proposed alteration on or before November 23, 1984.

77 FR 2545 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-18

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Designation of a Class of Employees for Addition to the... of Health and Human Services (HHS). ACTION: Notice. SUMMARY: HHS gives notice of a decision to designate a class of employees from the Pantex Plant in Amarillo, Texas, as an addition to the Special...

78 FR 26782 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; State...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-08

...: Administration for Community Living, HHS. ACTION: Notice. SUMMARY: The Administration for Community Living (ACL....eop.gov , Attn: OMB Desk Officer for ACL. FOR FURTHER INFORMATION CONTACT: Elena Fazio at 202-357-3583 or email: [email protected]acl.hhs.gov . SUPPLEMENTARY INFORMATION: In compliance with 44 U.S.C. 3507, ACL...

78 FR 70949 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-27

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for...). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of the HHS decision to designate a..., 1967, for a number of work days aggregating at least 250 work days, occurring either solely under this...

Preschool Inclusion: Key Findings from Research and Implications for Policy

ERIC Educational Resources Information Center

Lawrence, Sharmila; Smith, Sheila; Banerjee, Rashida

2016-01-01

A recent policy statement issued by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Education (DOE) on early childhood inclusion presents extensive recommendations for state and local actions that could improve young children's access to high quality inclusive early childhood programs (HHS/DOE, 2015). This brief…

78 FR 21954 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-12

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for...). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of the HHS decision to designate a... the period from April 16, 1943, through June 30, 1956, for a number of work days aggregating at least...

77 FR 60437 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-03

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for...). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of the HHS decision to designate a... August 1, 1949, through December 31, 1967, for a number of work days aggregating at least 250 work days...

EMERGING INFECTIOUS DISEASES. Actions Needed to Address the Challenges of Responding to Zika Virus Disease Outbreaks

DTIC Science & Technology

2017-05-01

Department of Health and Human Services 81 Appendix IV Zika Virus Case Definitions for National Notifiable Disease Reporting 86 Appendix V...Insecticide, Fungicide, and Rodenticide Act HHS Department of Health and Human Services IgG immunoglobulin G IgM immunoglobulin M IMM...Agency (EPA), and Department of Health and Human Services (HHS) including CDC, FDA and National Institutes of Health (NIH). We also convened, with

Asthma Action Plan Receipt among Children with Asthma 2-17 Years of Age, United States, 2002-2013.

PubMed

Simon, Alan E; Akinbami, Lara J

2016-04-01

To examine national trends in the receipt of asthma action plans, an intervention recommended by the National Asthma Education and Prevention Program guidelines. We used data from the sample child component of the National Health Interview Survey from 2002, 2003, 2008, and 2013 to examine the percentage of children 2-17 years of age with asthma (n = 3714) that have ever received an asthma action plan. Bivariate and multivariate (with adjustment for sociodemographic characteristics and asthma outcomes consistent with greater disease severity) logistic regressions were conducted to examine trends from 2002 to 2013 and to examine, with 2013 data only, the relationship between having received an asthma action plan and both sociodemographic characteristics and indicators of asthma severity. The percentage of children with asthma that had ever received an asthma action plan increased from 41.7% in 2002 to 50.7% in 2013 (P < .001 for trend). In 2013, a greater percentage of non-Hispanic black (58.4%) than non-Hispanic white (47.4%) children (P = .028), privately insured (56.2%) vs those with public insurance only (46.3%) (P = .016), and users of inhaled preventive asthma medication vs those that did not (P < .001) had ever received an asthma action plan. Adjusted results were similar. The percentage of US children with asthma that had ever received an asthma action plan increased between 2002 and 2013, although one-half had never received an asthma action plan in 2013. Some sociodemographic and asthma severity measures are related to receipt of an asthma action plan. Published by Elsevier Inc.

Preschool Inclusion: Key Findings from Research and Implications for Policy. Child Care and Early Education Research Connections

ERIC Educational Resources Information Center

Lawrence, Sharmila; Smith, Sheila; Banerjee, Rashida

2016-01-01

A recent policy statement issued by the U.S. Department of Health and Human Services (HHS) and U.S. Department of Education (DOE) on early childhood inclusion presents extensive recommendations for state and local actions that could improve young children's access to high quality inclusive preschool programs (HHS/DOE, 2015). This brief builds on…

Testing principle working mechanisms of the health action process approach for subjective physical age groups.

PubMed

Wienert, Julian; Kuhlmann, Tim; Fink, Sebastian; Hambrecht, Rainer; Lippke, Sonia

2016-01-01

This study investigated differences in social-cognitive predictors and self-regulatory planning, as proposed by the health action process approach (HAPA), across three different subjective physical age groups for physical activity. With a cross-sectional design, 521 participants across the chronological age span from 25 to 86 years (M = 48.79; SD = 12.66) were separated into three groups: those who feel physically younger than they are in terms of chronological age, the same perceived and chronological age, and feeling physically older compared to their chronological age. Participants were assessed regarding their perceived vulnerability, outcome expectancies, general intentions, planning, self-efficacy, and stages of physical activity (non-intenders, intenders, and actors). Data were analysed via mean comparison and multigroup structural equation modelling. Mean differences for all but one construct were eminent in all groups, generally showing that those feeling physically younger also report better social-cognitive predictors of physical activity (e.g. lower perceived vulnerability) in comparison to those who feel the same age or older. The model showed that basic working mechanisms of the HAPA can be applied to all groups. With that, the results provide for the first time evidence that principle working mechanism of the HAPA can be applied to all subjective physical age groups. These may be used to tailor health promoting interventions according to participants' needs as a more suitable proxy than chronological age.

INCENTIVES TO IDENTIFY: RACIAL IDENTITY IN THE AGE OF AFFIRMATIVE ACTION

PubMed Central

Antman, Francisca; Duncan, Brian

2016-01-01

We link data on racial self-identification with changes in state-level affirmative action policies to ask whether racial self-identification responds to economic incentives. We find that after a state bans affirmative action, multiracial individuals who face an incentive to identify under affirmative action are about 30 percent less likely to identify with their minority groups. In contrast, multiracial individuals who face a disincentive to identify under affirmative action are roughly 20 percent more likely to identify with their minority groups once affirmative action policies are banned. PMID:27635103

INCENTIVES TO IDENTIFY: RACIAL IDENTITY IN THE AGE OF AFFIRMATIVE ACTION.

PubMed

Antman, Francisca; Duncan, Brian

2015-07-01

We link data on racial self-identification with changes in state-level affirmative action policies to ask whether racial self-identification responds to economic incentives. We find that after a state bans affirmative action, multiracial individuals who face an incentive to identify under affirmative action are about 30 percent less likely to identify with their minority groups. In contrast, multiracial individuals who face a disincentive to identify under affirmative action are roughly 20 percent more likely to identify with their minority groups once affirmative action policies are banned.

Where is the action? Action sentence processing in Parkinson's disease

PubMed Central

Fernandino, Leonardo; Conant, Lisa L.; Binder, Jeffrey R.; Blindauer, Karen; Hiner, Bradley; Spangler, Katie; Desai, Rutvik H.

2013-01-01

According to an influential view of conceptual representation, action concepts are understood through motoric simulations, involving motor networks of the brain. A stronger version of this embodied account suggests that even figurative uses of action words (e.g., grasping the concept) are understood through motoric simulations. We investigated these claims by assessing whether Parkinson's disease (PD), a disorder affecting the motor system, is associated with selective deficits in comprehending action-related sentences. Twenty PD patients and 21 age-matched controls performed a sentence comprehension task, where sentences belonged to one of four conditions: literal action, non-idiomatic metaphoric action, idiomatic action, and abstract. The same verbs (referring to hand/arm actions) were used in the three action-related conditions. Patients, but not controls, were slower to respond to literal and idiomatic action than to abstract sentences. These results indicate that sensory-motor systems play a functional role in semantic processing, including processing of figurative action language. PMID:23624313

Functions of Aggression and Disciplinary Actions among Elementary School-Age Youth

ERIC Educational Resources Information Center

Fite, Paula J.; Evans, Spencer C.; Pederson, Casey A.; Tampke, Elizabeth C.

2017-01-01

Background: A link between aggression and disciplinary actions has been established; however, specific associations between reactive and proactive functions of aggression and disciplinary actions in the elementary school setting have not been evaluated. A better understanding of links between functions of aggression and disciplinary actions could…

Device costs go under the knife. With four hospitals having won HHS' approval for gain-sharing to shave supply costs, some observers say it's just the beginning.

PubMed

Becker, Cinda

2005-02-21

HHS' inspector general's office recently had some good news for four hospitals--they can use gain-sharing programs to help cut spending on devices. Joane Goodroe, left, is the consultant who helped the facilities devise proposals with safeguards that could satisfy the feds' worries about violating antikickback laws. "This is about paying physicians to take on the extra job of of reducing costs," Goodroe says.

Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).

PubMed

Bousquet, J; Farrell, J; Crooks, G; Hellings, P; Bel, E H; Bewick, M; Chavannes, N H; de Sousa, J Correia; Cruz, A A; Haahtela, T; Joos, G; Khaltaev, N; Malva, J; Muraro, A; Nogues, M; Palkonen, S; Pedersen, S; Robalo-Cordeiro, C; Samolinski, B; Strandberg, T; Valiulis, A; Yorgancioglu, A; Zuberbier, T; Bedbrook, A; Aberer, W; Adachi, M; Agusti, A; Akdis, C A; Akdis, M; Ankri, J; Alonso, A; Annesi-Maesano, I; Ansotegui, I J; Anto, J M; Arnavielhe, S; Arshad, H; Bai, C; Baiardini, I; Bachert, C; Baigenzhin, A K; Barbara, C; Bateman, E D; Beghé, B; Kheder, A Ben; Bennoor, K S; Benson, M; Bergmann, K C; Bieber, T; Bindslev-Jensen, C; Bjermer, L; Blain, H; Blasi, F; Boner, A L; Bonini, M; Bonini, S; Bosnic-Anticevitch, S; Boulet, L P; Bourret, R; Bousquet, P J; Braido, F; Briggs, A H; Brightling, C E; Brozek, J; Buhl, R; Burney, P G; Bush, A; Caballero-Fonseca, F; Caimmi, D; Calderon, M A; Calverley, P M; Camargos, P A M; Canonica, G W; Camuzat, T; Carlsen, K H; Carr, W; Carriazo, A; Casale, T; Cepeda Sarabia, A M; Chatzi, L; Chen, Y Z; Chiron, R; Chkhartishvili, E; Chuchalin, A G; Chung, K F; Ciprandi, G; Cirule, I; Cox, L; Costa, D J; Custovic, A; Dahl, R; Dahlen, S E; Darsow, U; De Carlo, G; De Blay, F; Dedeu, T; Deleanu, D; De Manuel Keenoy, E; Demoly, P; Denburg, J A; Devillier, P; Didier, A; Dinh-Xuan, A T; Djukanovic, R; Dokic, D; Douagui, H; Dray, G; Dubakiene, R; Durham, S R; Dykewicz, M S; El-Gamal, Y; Emuzyte, R; Fabbri, L M; Fletcher, M; Fiocchi, A; Fink Wagner, A; Fonseca, J; Fokkens, W J; Forastiere, F; Frith, P; Gaga, M; Gamkrelidze, A; Garces, J; Garcia-Aymerich, J; Gemicioğlu, B; Gereda, J E; González Diaz, S; Gotua, M; Grisle, I; Grouse, L; Gutter, Z; Guzmán, M A; Heaney, L G; Hellquist-Dahl, B; Henderson, D; Hendry, A; Heinrich, J; Heve, D; Horak, F; Hourihane, J O' B; Howarth, P; Humbert, M; Hyland, M E; Illario, M; Ivancevich, J C; Jardim, J R; Jares, E J; Jeandel, C; Jenkins, C; Johnston, S L; Jonquet, O; Julge, K; Jung, K S; Just, J; Kaidashev, I; Kaitov, M R; Kalayci, O; Kalyoncu, A F; Keil, T; Keith, P K; Klimek, L; Koffi N'Goran, B; Kolek, V; Koppelman, G H; Kowalski, M L; Kull, I; Kuna, P; Kvedariene, V; Lambrecht, B; Lau, S; Larenas-Linnemann, D; Laune, D; Le, L T T; Lieberman, P; Lipworth, B; Li, J; Lodrup Carlsen, K; Louis, R; MacNee, W; Magard, Y; Magnan, A; Mahboub, B; Mair, A; Majer, I; Makela, M J; Manning, P; Mara, S; Marshall, G D; Masjedi, M R; Matignon, P; Maurer, M; Mavale-Manuel, S; Melén, E; Melo-Gomes, E; Meltzer, E O; Menzies-Gow, A; Merk, H; Michel, J P; Miculinic, N; Mihaltan, F; Milenkovic, B; Mohammad, G M Y; Molimard, M; Momas, I; Montilla-Santana, A; Morais-Almeida, M; Morgan, M; Mösges, R; Mullol, J; Nafti, S; Namazova-Baranova, L; Naclerio, R; Neou, A; Neffen, H; Nekam, K; Niggemann, B; Ninot, G; Nyembue, T D; O'Hehir, R E; Ohta, K; Okamoto, Y; Okubo, K; Ouedraogo, S; Paggiaro, P; Pali-Schöll, I; Panzner, P; Papadopoulos, N; Papi, A; Park, H S; Passalacqua, G; Pavord, I; Pawankar, R; Pengelly, R; Pfaar, O; Picard, R; Pigearias, B; Pin, I; Plavec, D; Poethig, D; Pohl, W; Popov, T A; Portejoie, F; Potter, P; Postma, D; Price, D; Rabe, K F; Raciborski, F; Radier Pontal, F; Repka-Ramirez, S; Reitamo, S; Rennard, S; Rodenas, F; Roberts, J; Roca, J; Rodriguez Mañas, L; Rolland, C; Roman Rodriguez, M; Romano, A; Rosado-Pinto, J; Rosario, N; Rosenwasser, L; Rottem, M; Ryan, D; Sanchez-Borges, M; Scadding, G K; Schunemann, H J; Serrano, E; Schmid-Grendelmeier, P; Schulz, H; Sheikh, A; Shields, M; Siafakas, N; Sibille, Y; Similowski, T; Simons, F E R; Sisul, J C; Skrindo, I; Smit, H A; Solé, D; Sooronbaev, T; Spranger, O; Stelmach, R; Sterk, P J; Sunyer, J; Thijs, C; To, T; Todo-Bom, A; Triggiani, M; Valenta, R; Valero, A L; Valia, E; Valovirta, E; Van Ganse, E; van Hage, M; Vandenplas, O; Vasankari, T; Vellas, B; Vestbo, J; Vezzani, G; Vichyanond, P; Viegi, G; Vogelmeier, C; Vontetsianos, T; Wagenmann, M; Wallaert, B; Walker, S; Wang, D Y; Wahn, U; Wickman, M; Williams, D M; Williams, S; Wright, J; Yawn, B P; Yiallouros, P K; Yusuf, O M; Zaidi, A; Zar, H J; Zernotti, M E; Zhang, L; Zhong, N; Zidarn, M; Mercier, J

2016-01-01

Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care Pathways) was initiated using chronic respiratory diseases as a model. The chronic respiratory disease action plan includes (1) AIRWAYS integrated care pathways (ICPs), (2) the joint initiative between the Reference site MACVIA-LR (Contre les MAladies Chroniques pour un VIeillissement Actif) and ARIA (Allergic Rhinitis and its Impact on Asthma), (3) Commitments for Action to the European Innovation Partnership on Active and Healthy Ageing and the AIRWAYS ICPs network. It is deployed in collaboration with the World Health Organization Global Alliance against Chronic Respiratory Diseases (GARD). The European Innovation Partnership on Active and Healthy Ageing has proposed a 5-step framework for developing an individual scaling up strategy: (1) what to scale up: (1-a) databases of good practices, (1-b) assessment of viability of the scaling up of good practices, (1-c) classification of good practices for local replication and (2) how to scale up: (2-a) facilitating partnerships for scaling up, (2-b) implementation of key success factors and lessons learnt, including emerging technologies for individualised and predictive medicine. This strategy has already been applied to the chronic respiratory disease action plan of the European Innovation Partnership on Active and Healthy Ageing.

42 CFR 93.504 - Grounds for dismissal of a hearing request.

Code of Federal Regulations, 2011 CFR

2011-10-01

... research misconduct and any administrative actions, including debarment and suspension actions, in the... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.504 Grounds for dismissal of a hearing request. (a) The ALJ must...

42 CFR 93.504 - Grounds for dismissal of a hearing request.

Code of Federal Regulations, 2010 CFR

2010-10-01

... research misconduct and any administrative actions, including debarment and suspension actions, in the... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.504 Grounds for dismissal of a hearing request. (a) The ALJ must...

77 FR 40735 - Unique Device Identification System

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-10

... Identification System AGENCY: Food and Drug Administration, HHS. ACTION: Proposed rule. SUMMARY: The Food and... Regulatory Action This rule is intended to substantially reduce existing obstacles to the adequate... appropriate, better-focused, corrective action. The rule will also require dates on medical device labels to...

Minority Representation. Efforts of the Alcohol, Drug Abuse, and Mental Health Administration.

DTIC Science & Technology

1988-05-01

agencies, such as HHS, are required by law, executive order, and regulation to design and implement affirmative action programs. EEOC directed HHS to...outside ADAMHA from both the private and public sectors); and -. . . ., ’According to Equal Employment Opportunity Commission ( EEOC ) guidance...year 1988, we contacted an official in the Office of Federal Sector Pro- grams in EEOC and reviewed pertinent directives issued to federal agen- cies

78 FR 16401 - Institutional Review Boards; Correcting Amendments

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-15

... Administration, HHS. ACTION: Final rule; correcting amendments. SUMMARY: The Food and Drug Administration (FDA... the regulatory text and to update contact information. This action is editorial in nature and is... action under the Administrative Procedures Act (5 U.S.C. 553). FDA has determined that notice and public...

78 FR 19709 - Agency Information Collection Activities; Proposed Collection; Public Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-02

... Request Title: Evaluation of Implementation of the Viral Hepatitis Action Plan. Abstract: In response to the viral hepatitis epidemic in the United States, the Department of Health and Human Services (HHS) released the Action Plan for the Prevention, Care, and Treatment of Viral Hepatitis (Action Plan) in May...

Health Resources Priority and Allocations System (HRPAS). Interim final rule.

PubMed

2015-07-17

This interim final rule establishes standards and procedures by which the U.S. Department of Health and Human Services (HHS) may require that certain contracts or orders that promote the national defense be given priority over other contracts or orders. This rule also sets new standards and procedures by which HHS may allocate materials, services, and facilities to promote the national defense. This rule will implement HHS's administration of priorities and allocations actions, and establish the Health Resources Priorities and Allocation System (HRPAS). The HRPAS will cover health resources pursuant to the authority under Section 101(c) of the Defense Production Act as delegated to HHS by Executive Order 13603. Priorities authorities (and other authorities delegated to the Secretary in E.O. 13603, but not covered by this regulation) may be re-delegated by the Secretary. The Secretary retains the authority for allocations.

Relationship Between Age at Onset of Symptoms and Intraoperative Findings in Hip Arthroscopic Surgery

PubMed Central

Suarez-Ahedo, Carlos; Gui, Chengcheng; Rabe, Stephanie M.; Walsh, John P.; Chandrasekaran, Sivashankar; Domb, Benjamin G.

2017-01-01

Background: Hip arthroscopic surgery is intended to treat multiple abnormalities in an effort to delay the progression to osteoarthritis, especially in young patients. However, the length of time in which patients experience joint pain before seeking a specialist for a diagnosis can delay hip preservation surgery and influence clinical outcomes. Purpose: To investigate the relationship between age at symptom onset and findings during hip arthroscopic surgery as well as outcomes after 2 years of clinical follow-up. Study Design: Cohort study; Level of evidence, 3. Methods: From February 2008 to March 2015, data were prospectively collected on all patients undergoing hip arthroscopic surgery at a single institution. Anatomic and pathological characteristics were recorded intraoperatively. The mean age at onset of symptoms was calculated and correlated with intraoperative findings using Pearson correlation and logistic regression. All patients were assessed preoperatively and postoperatively with 4 patient-reported outcome measures: the modified Harris Hip Score (mHHS), the Non-Arthritic Hip Score (NAHS), the Hip Outcome Score–Activities of Daily Living (HOS-ADL), and the Hip Outcome Score–Sport-Specific Subscale (HOS-SSS). Pain was estimated using a visual analog scale (VAS). Furthermore, patients with an age at onset of symptoms below the mean (34.6 years) were compared with those of an age at onset of symptoms above the mean. The 2 groups were compared using the Student t test and the chi-square test. P values <.05 were considered significant. Results: A total of 1697 patients met the inclusion criteria. Body mass index was weakly correlated with age (r = 0.3). Younger patients had a lower prevalence of combined Seldes type 1 and 2 labral tears; acetabular labrum articular disruption (ALAD) grade 2, 3, and 4 acetabular chondral lesions; and Outerbridge grade 2, 3, and 4 femoral head chondral lesions (P < .05 for all). More advanced age was correlated with wider

Antidepressant-like effects of aniracetam in aged rats and its mode of action.

PubMed

Nakamura, K; Tanaka, Y

2001-11-01

Aniracetam has been reported to be efficacious for treating poststroke depression, but no studies that basically examined the antidepressive effects have been made. We aimed to test the antidepressant-like property of aniracetam in rats and to clarify the mechanisms of action through the interaction studies with some receptor antagonists. Antidepressant-like effects of aniracetam and various classes of compounds including different antidepressants were examined in a forced swim test with young (9 weeks old) and aged (25-30 months old) rats. Rats were exposed to a 5-min swim in a test session on day 2 following a 15-min swim in a training session on day 1, and immobility time during the period on day 2 was measured. The test compounds were administered subacutely (three doses over 2 days) or acutely (0.5 h before the testing). Standard antidepressants except for tandospirone significantly reduced immobility time in both young and aged rats. Aniracetam (10-100 mg/kg PO) failed to decrease immobility time in young rats, but it (100 mg/kg PO) significantly shortened immobility in aged rats, the effects of which were mainly mimicked by combined treatment of the metabolites, 2-pyrrolidinone and N-anisoyl-GABA. The effects of aniracetam was reversed completely by mecamylamine (10 mg/kg IP) or haloperidol (0.1 mg/kg IP) and slightly by ketanserin (1 m/kg IP) but was potentiated by scopolamine (0.03 mg/kg IP). These results indicate that aniracetam acts more effective when the forced swim stress-induced immobility is accompanied with brain dysfunction that occurs with aging. The antidepressant-like activity of aniracetam, which is probably due to the combined effects of 2-pyrrolidinone and N-anisoyl-GABA, may be mediated by mainly facilitating dopaminergic transmission (dopamine release and dopamine D2 receptor activation) through nicotinic acetylcholine receptor stimulation.

Using action research to build mentor capacity to improve orientation and quality of nursing students' aged care placements: what to do when the phone rings.

PubMed

Lea, Emma J; Andrews, Sharon; Stronach, Megan; Marlow, Annette; Robinson, Andrew L

2017-07-01

To describe whether an action research approach can be used to build capacity of residential aged care facility staff to support undergraduate nursing students' clinical placements in residential aged care facilities, using development of an orientation programme as an exemplar. Aged care facilities are unpopular sites for nursing students' clinical placements. A contributing factor is the limited capacity of staff to provide students with a positive placement experience. Strategies to build mentor capability to shape student placements and support learning and teaching are critical if nursing students are to have positive placements that attract them to aged care after graduation, an imperative given the increasing care needs of the ageing population worldwide. Action research approach employing mixed-methods data collection (primarily qualitative with a quantitative component). Aged care facility staff (n = 32) formed a mentor group at each of two Tasmanian facilities and met regularly to support undergraduate nursing students (n = 40) during placements. Group members planned, enacted, reviewed and reflected on orientation procedures to welcome students, familiarise them with the facility and prepare them for their placement. Data comprised transcripts from these and parallel student meetings, and orientation data from student questionnaires from two successive placement periods (2011/2012). Problems were identified in the orientation processes for the initial student placements. Mentors implemented a revised orientation programme. Evaluation demonstrated improved programme outcomes for students regarding knowledge of facility operations, their responsibilities and emergency procedures. Action research provides an effective approach to engage aged care facility staff to build their capacity to support clinical placements. Building capacity in the aged care workforce is vital to provide appropriate care for residents with increasing care needs. © 2016 John

42 CFR 93.503 - Grounds for granting a hearing request.

Code of Federal Regulations, 2011 CFR

2011-10-01

... findings of research misconduct or proposed administrative actions, including any debarment or suspension action. The respondent's general denial or assertion of error for each finding of research misconduct... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS...

42 CFR 93.503 - Grounds for granting a hearing request.

Code of Federal Regulations, 2010 CFR

2010-10-01

... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS... findings of research misconduct or proposed administrative actions, including any debarment or suspension action. The respondent's general denial or assertion of error for each finding of research misconduct...

[Anti-aging action of the total lactones of ginkgo on aging mice].

PubMed

Dong, Liu-yi; Fan, Li; Li, Gui-fang; Guo, Yan; Pan, Jian; Chen, Zhi-wu

2004-03-01

To investigate the effects of total lactones of ginkgo on aging by using D-galactose induced aging mice and natural aging mice. By using D-galactose induced aging mice, to detect the LF content in heart and liver, the Hyp content in liver, the MAO, GSH-Px activities and the NO content in cerebrum. The apoptosis of cerebral cell was determined by terminal deoxy-nucleotidyl transforase-mediated dUTP-digoxigenin nick end-labeling (Tunel) in natural aging mice. TLG was shown to increase the GSH-Px activities, reduce the NO content and decrease the MAO activity in cerebrum. Meanwhile, TLG was found to reduce the LF content in liver and heart and raise the Hyp content in liver. TLG was shown to inhibit apoptosis of cerebral cell and decrease the number of apoptotic cells in the brain. TLG possesses effect on antiaging via attenuating lipid peroxidation and NO and apoptosis of cerebral cells.

Nursing actions that create a sense of good nursing care in patients with wet age-related macular degeneration.

PubMed

Emsfors, Åsa; Christensson, Lennart; Elgán, Carina

2017-09-01

To identify and describe nursing actions performed by nurses that create a sense of good nursing care in patients with wet age-related macular degeneration. People who suffer from wet age-related macular degeneration risk central vision loss. Treatment with antivascular endothelial growth factor is the only available option at present that preserves vision and no definitive cure currently exists. Patients feel that they are compelled to accept this treatment because they might otherwise become blind. An explorative and descriptive design based on the critical incident technique was used. Interviews with 16 Swedish patients who all had received intravitreal treatment for wet age-related macular degeneration. Two main areas of good nursing care were identified: 'Being perceived as an individual' and 'Being empowered'. The first area was divided into two categories: being respectful and being engaged. Being respectful was observed when nurses had a benevolent attitude towards their patients and answered questions kindly and politely. Patients saw themselves as individuals when nurses were available for conversation and focused on them. The second area was divided into two categories: encouraging participation and creating confidence. Encouraging participation refers to when nurses provided information continuously. Nurses instilled confidence and trust in their patients by keeping promises and by being honest. A respectful interaction between patients and caregivers is necessary for patients to obtain beneficial health care. Patient interviews revealed important information about nursing actions that created a sense of good nursing care in patients with wet age-related macular degeneration. Nurses acknowledged people as individuals and created trust by building partnerships and sharing decision-making. To address each patient's concerns, nurses need to prioritise each patient's narrative and participation by documenting agreements in their medical record. © 2017 John

24 CFR 7.37 - Final action.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Final action. 7.37 Section 7.37..., Color Religion, Sex, National Origin, Age, Disability or Reprisal Complaints § 7.37 Final action. (a... include the remedial and corrective action necessary to ensure that the Department is in compliance with...

24 CFR 7.37 - Final action.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Final action. 7.37 Section 7.37..., Color Religion, Sex, National Origin, Age, Disability or Reprisal Complaints § 7.37 Final action. (a... include the remedial and corrective action necessary to ensure that the Department is in compliance with...

42 CFR 93.519 - Admissibility of evidence.

Code of Federal Regulations, 2011 CFR

2011-10-01

... RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.519 Admissibility of evidence. (a) The ALJ decides the admissibility of... of Witness). (i) Evidence about offers of compromise or settlement made in this action is...

42 CFR 93.519 - Admissibility of evidence.

Code of Federal Regulations, 2010 CFR

2010-10-01

... RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.519 Admissibility of evidence. (a) The ALJ decides the admissibility of... of Witness). (i) Evidence about offers of compromise or settlement made in this action is...

78 FR 25274 - Findings of Research Misconduct

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-30

... AGENCY: Office of the Secretary, HHS. ACTION: Notice. SUMMARY: Notice is hereby given that the Office of Research Integrity (ORI) has taken final action in the following case: Matthew Poore, Advanced Liquid Logic... that Respondent knowingly and intentionally falsified reverse transcription-polymerase chain reaction...

Moral Judgment in Old Age.

PubMed

Margoni, Francesco; Geipel, Janet; Hadjichristidis, Constantinos; Surian, Luca

2018-03-01

Younger (21-39 years) and older (63-90 years) adults were presented with scenarios illustrating either harmful or helpful actions. Each scenario provided information about the agent's intention, either neutral or valenced (harmful/helpful), and the outcome of his or her action, either neutral or valenced. Participants were asked to rate how morally good or bad the agent's action was. In judging harmful actions, older participants relied less on intentions and more on outcomes compared to younger participants. This age-related difference was associated with a decline in older adults' theory of mind abilities. However, we did not find evidence of any significant age-related difference in the evaluations of helpful actions. We argue that the selective association of aging with changes in the evaluation of harmful but not helpful actions may be due also to motivational factors and highlight some implications of the present findings for judicial systems.

Action Imitation at 1.5 Years Is Better than Pointing Gesture in Predicting Late Development of Language Production at 3 Years of Age

ERIC Educational Resources Information Center

Zambrana, Imac M.; Ystrom, Eivind; Schjolberg, Synnve; Pons, Francisco

2013-01-01

This study examined whether poor pointing gestures and imitative actions at 18 months of age uniquely predicted late language production at 36 months, beyond the role of poor language at 18 months of age. Data from the Norwegian Mother and Child Cohort Study were utilized. Maternal reports of the children's nonverbal skills and language were…

Translation, cross-cultural adaptation, and validation of the Turkish version of the Harris Hip Score.

PubMed

Çelik, Derya; Can, Canan; Aslan, Yasemin; Ceylan, Hasan Huseyin; Bilsel, Kerem; Ozdincler, Arzu Razak

2014-01-01

The Harris Hip Score (HHS) developed to assess function and pain from the perspective of patients hip pathologies. The purpose of this study was to translate and culturally adapt the HHS into Turkish, and thereby determine the reliability and validity of the translated version. The HHS was translated into Turkish in accordance with the stages recommended by Beaton. The measurement properties of the HHS were tested in 80 patients; 52 males, mean age 51 years (range 21-75 years) suffering from different hip pathologies. The test-retest reliability was tested in 58 patients; 28 males mean age, 52 years (range 30-73 years) after an interval of seven days. The Cronbach's Alpha was used to assess internal consistency and the intra-class correlation coefficient (ICC) was used to estimate the test-retest reliability. Patients were asked to answer the Oxford Hip Score (OHS), the Western Ontario and McMaster Universities Arthritis Index (WOMAC), the VAS and the Short Form-36 (SF-36) for the validity of the estimation. The Turkish version of the HHS showed sufficient internal consistency (Cronbach's alpha,0.70) and test-retest reliability (ICC = 0.91). The correlation coefficients between the HHS, the WOMAC and the OHS were 0.64 and 0.89 respectively. The highest correlations between the HHS and SF-36 were with the physical function scale (r = 0.72), and the lowest correlations were with the mental function scale (r = 0.10). We observed no floor or ceiling effects. The Turkish version of the HHS has sufficient reliability and validity to measure patient-reported outcome for Turkish-speaking individuals with a variety of hip disorders.

42 CFR 93.518 - Witnesses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing...

76 FR 3143 - Determination That ALBAMYCIN (Novobiocin Sodium) Capsule, 250 Milligrams, Was Withdrawn From Sale...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-19

... Safety or Effectiveness AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and... adverse reactions include relatively common skin reactions, jaundice, hepatic failure, and blood...

76 FR 41264 - Agency Information Collection Activities; Announcement of Office of Management and Budget...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-13

...; Cosmetic Labeling Regulations AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing that a collection of information entitled ``Cosmetic...

75 FR 78249 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-15

... 505(q) of the Federal Food, Drug, and Cosmetic Act AGENCY: Food and Drug Administration, HHS. ACTION... Petitions for Stay of Action Subject to Section 505(q) of the Federal Food, Drug, and Cosmetic Act.'' Also... Petitions for Stay of Action Subject to Section 505(q) of the Federal Food, Drug, and Cosmetic Act In the...

76 FR 11794 - Drugs for Human Use; Unapproved and Misbranded Oral Drugs Labeled for Prescription Use and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-03

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0100... Relief of Symptoms of Cold, Cough, or Allergy; Enforcement Action Dates AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing its intention...

77 FR 40069 - Single-Ingredient, Immediate-Release Drug Products Containing Oxycodone for Oral Administration...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0563... Labeled for Human Use; Enforcement Action Dates AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA or Agency) is announcing its intention to take enforcement...

78 FR 79701 - Tentative Determination Regarding Partially Hydrogenated Oils; Request for Comments and for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-31

... therefore are subject to regulation as food additives. We are taking this action in response to multiple... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-1317... and Information; Extension of Comment Period AGENCY: Food and Drug Administration, HHS. ACTION: Notice...

Action Learning as Invigoration

ERIC Educational Resources Information Center

Chivers, Terence S.

2011-01-01

The present account of action learning describes its adoption for pragmatic reasons by the University of the Third Age (U3A). The reason for the existence of this movement is the education of retired people. The account seeks to explain why the action learning method spread from one local U3A to another and across it to other local U3As. The case…

75 FR 67983 - Agency Information Collection Activities; Announcement of Office of Management and Budget...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-04

...; Infant Formula Requirements AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing that a collection of information entitled ``Infant Formula...

42 CFR 93.509 - Computation of time.

Code of Federal Regulations, 2010 CFR

2010-10-01

... EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing...

42 CFR 93.505 - Rights of the parties.

Code of Federal Regulations, 2011 CFR

2011-10-01

... EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing...

76 FR 40734 - Agency Information Collection Activities; Announcement of Office of Management and Budget...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-11

...; Voluntary Cosmetic Registration Program AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY... ``Voluntary Cosmetic Registration Program'' has been approved by the Office of Management and Budget [[Page...

Emerging Perception of Causality in Action-and-Reaction Sequences from 4 to 6 Months of Age: Is It Domain-Specific?

ERIC Educational Resources Information Center

Schlottmann, Anne; Ray, Elizabeth D.; Surian, Luca

2012-01-01

Two experiments (N=136) studied how 4- to 6-month-olds perceive a simple schematic event, seen as goal-directed action and reaction from 3 years of age. In our causal reaction event, a red square moved toward a blue square, stopping prior to contact. Blue began to move away before red stopped, so that both briefly moved simultaneously at a…

42 CFR 93.506 - Authority of the Administrative Law Judge.

Code of Federal Regulations, 2011 CFR

2011-10-01

... POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.506 Authority of the Administrative Law Judge. (a) The ALJ assigned... communication; (17) Take action against any party for failing to follow an order or procedure or for disruptive...

78 FR 9010 - Dental Devices; Reclassification of Temporary Mandibular Condyle Prosthesis

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-07

...: Food and Drug Administration, HHS. ACTION: Proposed order. SUMMARY: The Food and Drug Administration... for subsequent action where the reevaluation is made in light of newly available authority (see Bell... the plate or screws through the skin. Mechanical wear of the plate or screws and foreign body reaction...

42 CFR 93.513 - Submission of witness lists, witness statements, and exhibits.

Code of Federal Regulations, 2011 CFR

2011-10-01

... FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.513 Submission of witness lists...

42 CFR 93.507 - Ex parte communications.

Code of Federal Regulations, 2011 CFR

2011-10-01

... RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.507 Ex parte communications. (a) No party, attorney, or other party...

42 CFR 93.513 - Submission of witness lists, witness statements, and exhibits.

Code of Federal Regulations, 2010 CFR

2010-10-01

... FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.513 Submission of witness lists...

76 FR 78931 - Food and Drug Administration Rare Disease Patient Advocacy Day; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-20

... Administration, HHS. ACTION: Notice. The Food and Drug Administration's (FDA) Office of Orphan Products... educate the rare disease community on the FDA regulatory processes. This educational meeting will consist...

78 FR 20671 - Prospective Grant of A Start-Up Commercialization Exclusive License: The Development of Fenoterol...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-05

... Brain and Hepatocellular Cancers AGENCY: National Institutes of Health, HHS. ACTION: Notice. SUMMARY..., and use in humans for the treatment of brain cancer or hepatocellular cancer within the Licensed...

Child-Mediated Stroke Communication: Findings from Hip Hop Stroke

PubMed Central

Williams, Olajide; DeSorbo, Alexandra; Noble, James; Gerin, William

2011-01-01

Background and Purpose Low thrombolysis rates for acute ischemic stroke is linked to delays in seeking immediate treatment due to low public stroke awareness. We aimed to assess whether “Child-Mediated Stroke Communication” (CMSC) could improve stroke literacy parents of children enrolled in a school-based stroke literacy program called Hip Hop Stroke (HHS). Methods Parents of children aged 9 to 12 years from two public schools in Harlem, NYC, were recruited to participate in stroke literacy questionnaires before and after their child’s participation in HHS, a novel CMSC intervention delivered in school auditoriums. Parental recall of stroke information communicated through their child was assessed 1-week following the intervention. Results Fifth and Sixth grade students (n =182) were enrolled into HHS. 102 parents were approached in person to participate; 75 opted to participate and 71 completed both pretest and post-test (74% response rate and 95% retention rate). Parental stroke literacy improved after the program: before the program, 3 parents of 75 (3.9%) were able to identify the five cardinal stroke symptoms, distracting symptom (chest pains), and had an urgent action plan (calling 911), compared to 21 of 71 parents (29.6%) post-intervention (p<0.001). The FAST mnemonic was known by 2 (2.7%) of participants before the program vs. 29 (41%) after program completion (p<0.001). Conclusions Knowledge of stroke signs and symptoms remains low among residents of this high-risk population. The use of Child-Mediated Stroke Communication suggests that schoolchildren aged 9-12 may be effective conduits of critical stroke knowledge to their Parents. PMID:22033995

76 FR 31345 - Cooperative Arrangement Between the United States Food and Drug Administration and the Inter...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-31

... Institute for Cooperation in Agriculture AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY... and the Inter-American Institute for Cooperation in Agriculture. The purpose of the arrangement is to...

1982 HHS/LIHEAP funds used for weatherization. An analysis of data from twenty states: Task A. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1983-05-01

During the Summer and Fall of 1982, Arawak Consulting Corporation monitored a number of program management functions of the Low Income Weatherization Assistance Program (WAP) in the 20 states under the jurisdiction of the DOE Chicago Operations Office. The monitoring included on-site visits to all 20 state grantees and 85 randomly selected local subgrantees. Although the monitoring was designed to focus only on the DOE funded program, it soon became apparent that funds from the Department of Health and Human Services' Low Income Home Energy Assistance Program (LIHEAP) often had a significant effect on the scope and mode of operationmore » of the weatherization program. As a result of these and other outcomes, DOE asked Arawak to further study the impact of HHS funds on the Weatherization Assistance Program in the same 20 states. This report is the result of that request. It draws on information collected during the monitoring visits which were conducted from mid-July to mid-October 1982, and on additional information obtained in telephone interviews during the last two weeks of February 1983.« less

78 FR 60288 - Agency Information Collection Activities: Proposed Collection; Comment Request; Guidance for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-01

..., and Cosmetic Act AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug... Cosmetic Act (FD&C Act). DATES: Submit either electronic or written comments on the collection of... Petitions for Stay of Action Subject to Section 505(q) of the Federal Food, Drug, and Cosmetic Act--(OMB...

42 CFR 93.522 - Filing post-hearing briefs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.522 Filing post-hearing briefs. (a) After the hearing and under a schedule...

42 CFR 93.522 - Filing post-hearing briefs.

Code of Federal Regulations, 2011 CFR

2011-10-01

... RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.522 Filing post-hearing briefs. (a) After the hearing and under a schedule...

75 FR 62840 - Award of a Single-Source Expansion Supplement to the University of Oklahoma, National Resource...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-13

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Award of a Single... AGENCY: Children's Bureau, ACYF, ACF, HHS. ACTION: Notice. CFDA Number: 93.674. Legislative Authority.... [[Page 62841

44 CFR 7.924 - Affirmative action by recipient.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Affirmative action by... Standards for Determining Age Discrimination § 7.924 Affirmative action by recipient. Even in the absence of a finding of discrimination, a recipient may take affirmative action to overcome the effects of...

44 CFR 7.924 - Affirmative action by recipient.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Affirmative action by... Standards for Determining Age Discrimination § 7.924 Affirmative action by recipient. Even in the absence of a finding of discrimination, a recipient may take affirmative action to overcome the effects of...

28 CFR 42.724 - Remedial and affirmative action.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Remedial and affirmative action. 42.724... affirmative action. (a) If the Department finds that, in violation of this subpart, a recipient has discriminated on the basis of age, the recipient shall take remedial action that the Department considers...

28 CFR 42.724 - Remedial and affirmative action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Remedial and affirmative action. 42.724... affirmative action. (a) If the Department finds that, in violation of this subpart, a recipient has discriminated on the basis of age, the recipient shall take remedial action that the Department considers...

76 FR 30369 - Agency Information Collection Activities; Announcement of Office of Management and Budget...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-25

...; Experimental Study of Nutrition Facts Label Formats AGENCY: Food and Drug Administration, HHS. ACTION: Notice... ``Experimental Study of Nutrition Facts Label Formats'' has been approved by the Office of Management and Budget...

42 CFR 93.521 - Correction of the transcript.

Code of Federal Regulations, 2011 CFR

2011-10-01

... RESEARCH MISCONDUCT Opportunity To Contest ORI Findings of Research Misconduct and HHS Administrative Actions Hearing Process § 93.521 Correction of the transcript. (a) At any time, but not later than the...

38 CFR 18.516 - Affirmative action by recipients.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Affirmative action by... Determining Age Discrimination § 18.516 Affirmative action by recipients. Even in the absence of a finding of discrimination, a recipient may take affirmative action to overcome the effects of conditions that resulted in...

34 CFR 110.15 - Affirmative action by recipients.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 1 2011-07-01 2011-07-01 false Affirmative action by recipients. 110.15 Section 110.15... ASSISTANCE Standards for Determining Age Discrimination § 110.15 Affirmative action by recipients. Even in the absence of a finding of discrimination, a recipient may take affirmative action to overcome the...

45 CFR 91.16 - Affirmative action by recipient.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 1 2011-10-01 2011-10-01 false Affirmative action by recipient. 91.16 Section 91... for Determining Age Discrimination § 91.16 Affirmative action by recipient. Even in the absence of a finding of discrimination, a recipient may take affirmative action to overcome the effects of conditions...

43 CFR 17.315 - Affirmative action by recipients.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Affirmative action by recipients. 17.315... Standards for Determining Age Discrimination § 17.315 Affirmative action by recipients. Even in the absence of a finding of discrimination, a recipient may take affirmative action to overcome the effects of...

43 CFR 17.315 - Affirmative action by recipients.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Affirmative action by recipients. 17.315... Standards for Determining Age Discrimination § 17.315 Affirmative action by recipients. Even in the absence of a finding of discrimination, a recipient may take affirmative action to overcome the effects of...

38 CFR 18.516 - Affirmative action by recipients.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Affirmative action by... Determining Age Discrimination § 18.516 Affirmative action by recipients. Even in the absence of a finding of discrimination, a recipient may take affirmative action to overcome the effects of conditions that resulted in...

34 CFR 110.15 - Affirmative action by recipients.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Affirmative action by recipients. 110.15 Section 110.15... ASSISTANCE Standards for Determining Age Discrimination § 110.15 Affirmative action by recipients. Even in the absence of a finding of discrimination, a recipient may take affirmative action to overcome the...

45 CFR 91.16 - Affirmative action by recipient.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Affirmative action by recipient. 91.16 Section 91... for Determining Age Discrimination § 91.16 Affirmative action by recipient. Even in the absence of a finding of discrimination, a recipient may take affirmative action to overcome the effects of conditions...

29 CFR 35.15 - Remedial action.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true Remedial action. 35.15 Section 35.15 Labor Office of the Secretary of Labor NONDISCRIMINATION ON THE BASIS OF AGE IN PROGRAMS OR ACTIVITIES RECEIVING FEDERAL... Remedial action. Even in the absence of a finding of discrimination, a recipient, in administering a...

Affirmative Action Plan.

ERIC Educational Resources Information Center

North Carolina State Dept. of Public Instruction, Raleigh.

This affirmative action (AA) guide is intended to identify and remove discriminatory employment practices that may still exist in the North Carolina State Department of Public Instruction (DPI). DPI extends equal employment opportunity (EEO) to all applicants and employees without regard to race, color, religion, sex, age, handicap, political…

75 FR 25296 - Workforce Investment Act; Lower Living Standard Income Level

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-07

... period that does not exceed the higher level of the poverty line or 70 percent of the LLSIL. This... Services ``Poverty Guidelines.'' Congress has taken action to keep the 2009 HHS poverty guidelines in...

Global form and motion processing in healthy ageing.

PubMed

Agnew, Hannah C; Phillips, Louise H; Pilz, Karin S

2016-05-01

The ability to perceive biological motion has been shown to deteriorate with age, and it is assumed that older adults rely more on the global form than local motion information when processing point-light walkers. Further, it has been suggested that biological motion processing in ageing is related to a form-based global processing bias. Here, we investigated the relationship between older adults' preference for form information when processing point-light actions and an age-related form-based global processing bias. In a first task, we asked older (>60years) and younger adults (19-23years) to sequentially match three different point-light actions; normal actions that contained local motion and global form information, scrambled actions that contained primarily local motion information, and random-position actions that contained primarily global form information. Both age groups overall performed above chance in all three conditions, and were more accurate for actions that contained global form information. For random-position actions, older adults were less accurate than younger adults but there was no age-difference for normal or scrambled actions. These results indicate that both age groups rely more on global form than local motion to match point-light actions, but can use local motion on its own to match point-light actions. In a second task, we investigated form-based global processing biases using the Navon task. In general, participants were better at discriminating the local letters but faster at discriminating global letters. Correlations showed that there was no significant linear relationship between performance in the Navon task and biological motion processing, which suggests that processing biases in form- and motion-based tasks are unrelated. Copyright © 2016. Published by Elsevier B.V.

Higher levels of motor competence are associated with reduced interference in action perception across the lifespan.

PubMed

Wermelinger, Stephanie; Gampe, Anja; Daum, Moritz M

2017-11-07

Action perception and action production are tightly linked and elicit bi-directional influences on each other when performed simultaneously. In this study, we investigated whether age-related differences in manual fine-motor competence and/or age affect the (interfering) influence of action production on simultaneous action perception. In a cross-sectional eye-tracking study, participants of a broad age range (N = 181, 20-80 years) observed a manual grasp-and-transport action while performing an additional motor or cognitive distractor task. Action perception was measured via participants' frequency of anticipatory gaze shifts towards the action goal. Manual fine-motor competence was assessed with the Motor Performance Series. The interference effect in action perception was greater in the motor than the cognitive distractor task. Furthermore, manual fine-motor competence and age in years were both associated with this interference. The better the participants' manual fine-motor competence and the younger they were, the smaller the interference effect. However, when both influencing factors (age and fine-motor competence) were taken into account, a model including only age-related differences in manual fine-motor competence best fit with our data. These results add to the existing literature that motor competence and its age-related differences influence the interference effects between action perception and production.

29 CFR 35.39 - Remedial action by recipient.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Enforcement Procedures § 35.39 Remedial action by recipient. Where CRC finds discrimination on the basis of age in violation of this Act or this part, the recipient shall take any remedial action that CRC deems...

78 FR 54256 - Health Careers Opportunity Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-03

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Health Careers Opportunity Program AGENCY: Health Resources and Services Administration (HRSA), HHS. ACTION: Notice of Noncompetitive Program Expansion Supplements to Health Careers Opportunity Program (HCOP...

77 FR 2734 - Health Information Technology Implementation

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-19

... Information Technology Implementation AGENCY: Health Resources and Services Administration, HHS. ACTION... Technology Implementation for Health Center Controlled Networks (HCCN) funds originally awarded to Community... advance information technology resources of the Tennessee's medically underserved communities, TPCA has...

Humanin: A Novel Central Regulator of Peripheral Insulin Action

PubMed Central

Muzumdar, Radhika H.; Huffman, Derek M.; Atzmon, Gil; Buettner, Christoph; Cobb, Laura J.; Fishman, Sigal; Budagov, Temuri; Cui, Lingguang; Einstein, Francine H.; Poduval, Aruna; Hwang, David; Barzilai, Nir; Cohen, Pinchas

2009-01-01

Background Decline in insulin action is a metabolic feature of aging and is involved in the development of age-related diseases including Type 2 Diabetes Mellitus (T2DM) and Alzheimer's disease (AD). A novel mitochondria-associated peptide, Humanin (HN), has a neuroprotective role against AD-related neurotoxicity. Considering the association between insulin resistance and AD, we investigated if HN influences insulin sensitivity. Methods and Findings Using state of the art clamp technology, we examined the role of central and peripheral HN on insulin action. Continuous infusion of HN intra-cerebro-ventricularly significantly improved overall insulin sensitivity. The central effects of HN on insulin action were associated with activation of hypothalamic STAT-3 signaling; effects that were negated by co-inhibition of hypothalamic STAT-3. Peripheral intravenous infusions of novel and potent HN derivatives reproduced the insulin-sensitizing effects of central HN. Inhibition of hypothalamic STAT-3 completely negated the effects of IV HN analog on liver, suggesting that the hepatic actions of HN are centrally mediated. This is consistent with the lack of a direct effect of HN on primary hepatocytes. Furthermore, single treatment with a highly-potent HN analog significantly lowered blood glucose in Zucker diabetic fatty rats. Based upon the link of HN with two age-related diseases, we examined if there were age associated changes in HN levels. Indeed, the amount of detectable HN in hypothalamus, skeletal muscle, and cortex was decreased with age in rodents, and circulating levels of HN were decreased with age in humans and mice. Conclusions We conclude that the decline in HN with age could play a role in the pathogenesis of age-related diseases including AD and T2DM. HN represents a novel link between T2DM and neurodegeneration and along with its analogues offers a potential therapeutic tool to improve insulin action and treat T2DM. PMID:19623253

Elder care - resources

MedlinePlus

Resources - elder care ... The following organizations are good resources for information on aging and elder care: Administration on Aging -- www.hhs.gov/aging/long-term-care/index.html Eldercare Locator -- ...

Resources for the Aging: An Action Handbook.

ERIC Educational Resources Information Center

National Council on the Aging, Inc., New York, NY.

This handbook on resources for the aging lists nationwide, federally sponsored programs, national voluntary agencies and associations, and foundations; it includes information on the nature and purpose of the program, types of projects sponsored, and extent of assistance, eligibility requirements, available printed information, sources of further…

75 FR 73107 - Draft Guidance for Industry on Hospital-Acquired Bacterial Pneumonia and Ventilator-Associated...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-29

...] Draft Guidance for Industry on Hospital-Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial Pneumonia: Developing Drugs for Treatment; Availability AGENCY: Food and Drug Administration, HHS. ACTION... guidance for industry entitled ``Hospital- Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial...

75 FR 2549 - Health Center Program

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2010-01-15

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Health Center Program AGENCY: Health Resources and Services Administration, HHS ACTION: Notice of Noncompetitive Replacement Award to Regional Health Care Affiliates. SUMMARY: The Health Resources and Services...

76 FR 53377 - Negotiated Rulemaking Committee on Designation of Medically Underserved Populations and Health...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-26

... DEPARTMENT OF HEALTH AND HUMAN SERVICES 42 CFR Part 5 Negotiated Rulemaking Committee on Designation of Medically Underserved Populations and Health Professional Shortage Areas; Notice of Meeting AGENCY: Health Resources and Services Administration, HHS. ACTION: Negotiated Rulemaking Committee...

76 FR 10825 - Negotiated Rulemaking Committee on Designation of Medically Underserved Populations and Health...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-28

... DEPARTMENT OF HEALTH AND HUMAN SERVICES 42 CFR Part 5 Negotiated Rulemaking Committee on Designation of Medically Underserved Populations and Health Professional Shortage Areas; Notice of Meeting AGENCY: Health Resources and Services Administration, HHS. ACTION: Negotiated Rulemaking Committee...

76 FR 61294 - Negotiated Rulemaking Committee on Designation of Medically Underserved Populations and Health...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-04

... DEPARTMENT OF HEALTH AND HUMAN SERVICES 42 CFR Part 5 Negotiated Rulemaking Committee on Designation of Medically Underserved Populations and Health Professional Shortage Areas; Notice of Meeting AGENCY: Health Resources and Services Administration, HHS. ACTION: Negotiated Rulemaking Committee...

AgeFactDB--the JenAge Ageing Factor Database--towards data integration in ageing research.

PubMed

Hühne, Rolf; Thalheim, Torsten; Sühnel, Jürgen

2014-01-01

AgeFactDB (http://agefactdb.jenage.de) is a database aimed at the collection and integration of ageing phenotype data including lifespan information. Ageing factors are considered to be genes, chemical compounds or other factors such as dietary restriction, whose action results in a changed lifespan or another ageing phenotype. Any information related to the effects of ageing factors is called an observation and is presented on observation pages. To provide concise access to the complete information for a particular ageing factor, corresponding observations are also summarized on ageing factor pages. In a first step, ageing-related data were primarily taken from existing databases such as the Ageing Gene Database--GenAge, the Lifespan Observations Database and the Dietary Restriction Gene Database--GenDR. In addition, we have started to include new ageing-related information. Based on homology data taken from the HomoloGene Database, AgeFactDB also provides observation and ageing factor pages of genes that are homologous to known ageing-related genes. These homologues are considered as candidate or putative ageing-related genes. AgeFactDB offers a variety of search and browse options, and also allows the download of ageing factor or observation lists in TSV, CSV and XML formats.

AgeFactDB—the JenAge Ageing Factor Database—towards data integration in ageing research

PubMed Central

Hühne, Rolf; Thalheim, Torsten; Sühnel, Jürgen

2014-01-01

AgeFactDB (http://agefactdb.jenage.de) is a database aimed at the collection and integration of ageing phenotype data including lifespan information. Ageing factors are considered to be genes, chemical compounds or other factors such as dietary restriction, whose action results in a changed lifespan or another ageing phenotype. Any information related to the effects of ageing factors is called an observation and is presented on observation pages. To provide concise access to the complete information for a particular ageing factor, corresponding observations are also summarized on ageing factor pages. In a first step, ageing-related data were primarily taken from existing databases such as the Ageing Gene Database—GenAge, the Lifespan Observations Database and the Dietary Restriction Gene Database—GenDR. In addition, we have started to include new ageing-related information. Based on homology data taken from the HomoloGene Database, AgeFactDB also provides observation and ageing factor pages of genes that are homologous to known ageing-related genes. These homologues are considered as candidate or putative ageing-related genes. AgeFactDB offers a variety of search and browse options, and also allows the download of ageing factor or observation lists in TSV, CSV and XML formats. PMID:24217911

Multicenter Analysis of Midterm Clinical Outcomes of Arthroscopic Labral Repair in the Hip: Minimum 5-Year Follow-up.

PubMed

Hevesi, Mario; Krych, Aaron J; Johnson, Nick R; Redmond, John M; Hartigan, David E; Levy, Bruce A; Domb, Benjamin G

2018-02-01

The technique of hip arthroscopic surgery is advancing and becoming more commonly performed. However, most current reported results are limited to short-term follow-up, and therefore, the durability of the procedure is largely unknown. To perform a multicenter analysis of mid-term clinical outcomes of arthroscopic hip labral repair and determine the risk factors for patient outcomes. Cohort study; Level of evidence, 3. Prospectively collected data of primary hip arthroscopic labral repair performed at 4 high-volume centers between 2008 and 2011 were reviewed retrospectively. Patients were assessed preoperatively and postoperatively with the visual analog scale (VAS), modified Harris Hip Score (mHHS), and Hip Outcome Score-Sports-Specific Subscale (HOS-SSS) at a minimum of 5 years' follow-up. Factors including age, body mass index (BMI), Tönnis grade, and cartilage grade were analyzed in relation to outcome scores, and revision rates were determined. Failure was defined as subsequent ipsilateral hip surgery, including revision arthroscopic surgery and open hip surgery. A total of 303 patients (101 male, 202 female) with a mean age of 32.0 years (range, 10.7-58.9 years) were followed for a mean of 5.7 years (range, 5.0-7.9 years). Patients achieved mean improvements in VAS of 3.5 points, mHHS of 20.1 points, and HOS-SSS of 29.3 points. Thirty-seven patients (12.2%) underwent revision arthroscopic surgery, and 12 (4.0%) underwent periacetabular osteotomy, resurfacing, or total hip arthroplasty during the study period. Patients with a BMI >30 kg/m 2 had a mean mHHS score 9.5 points lower and a mean HOS-SSS score 15.9 points lower than those with a BMI ≤30 kg/m 2 ( P < .01). Patients aged >35 years at surgery had a mean mHHS score 4.5 points lower and a HOS-SSS score 6.7 points lower than those aged ≤35 years ( P = .03). Patients with Tönnis grade 2 radiographs demonstrated a 12.5-point worse mHHS score ( P = .02) and a 23.0-point worse HOS-SSS score ( P < .01

CE: Viral Hepatitis: New U.S. Screening Recommendations, Assessment Tools, and Treatments.

PubMed

Dan, Corinna; Moses-Eisenstein, Michelle; Valdiserri, Ronald O

2015-07-01

Over the past 15 years, the incidences of hepatitis A and B virus infection in the United States have declined significantly. By contrast, the incidence of hepatitis C virus infection, formerly stable or in decline, has increased by 75% since 2010. Suboptimal therapies of the past, insufficient provider awareness, and low screening rates have hampered efforts to improve diagnosis, management, and treatment of viral hepatitis. New screening recommendations, innovations in assessment and treatment, and an updated action plan from the U.S. Department of Health and Human Services (HHS) seem likely to lead to significant progress in the coming years. This article reviews the epidemiology, natural history, and diagnosis of viral hepatitis; discusses new screening recommendations, assessment tools, and treatments; and outlines the HHS action plan, focusing on the role of nurses in prevention and treatment.

Inverse relationship between ambient temperature and admissions for diabetic ketoacidosis and hyperglycemic hyperosmolar state: A 14-year time-series analysis.

PubMed

Lu, Chin-Li; Chang, Hsin-Hui; Chen, Hua-Fen; Ku, Li-Jung Elizabeth; Chang, Ya-Hui; Shen, Hsiu-Nien; Li, Chung-Yi

2016-09-01

This study aimed to investigate the association of admissions for diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) with ambient temperature and season, respectively in patients with diabetes mellitus (DM), after excluding known co-morbidities that predispose onset of acute hyperglycemia events. This was a time series correlation analysis based on medical claims of 40,084 and 33,947 episodes of admission for DKA and HHS, respectively over a 14-year period in Taiwan. These episodes were not accompanied by co-morbidities known to trigger incidence of DKA and HHS. Monthly temperature averaged from 19 meteorological stations across Taiwan was correlated with monthly rate of admission for DKA or HHS, respectively, using the 'seasonal Autoregressive Integrated Moving Average' (seasonal ARIMA) regression method. There was an inverse relationship between ambient temperature and rates of admission for DKA (β=-0.035, p<0.001) and HHS (β=-0.016, p<0.001), despite a clear decline in rates of DKA/HHS admission in the second half of the study period. We also noted that winter was significantly associated with increased rates of both DKA (β=0.364, p<0.001) and HHS (β=0.129, p<0.05) admissions, as compared with summer. On the other hand, fall was associated with a significantly lower rate of HHS admission (β=-0.016, p<0.05). Further stratified analyses according to sex and age yield essentially similar results. It is suggested that meteorological data can be used to raise the awareness of acute hyperglycemic complication risk for both patients with diabetes and clinicians to further avoid the occurrence of DKA and HHS. Copyright © 2016 Elsevier Ltd. All rights reserved.

76 FR 34079 - Agency Information Collection Activities; Proposed Collection; Comment Request; Regulations for...

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2011-06-10

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78 FR 30312 - Agency Information Collection Activities; Proposed Collection; Comment Request; Requests for...

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2013-05-22

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2013-04-26

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2011-01-10

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75 FR 21001 - Health Center Program

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2010-04-22

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76 FR 17139 - Health Center Program

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2011-03-28

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75 FR 1792 - Maternal and Child Health Bureau

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2010-01-13

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77 FR 62243 - Rural Health Network Development Program

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2012-10-12

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78 FR 2997 - Administration on Intellectual and Developmental Disabilities (AIDD); Notice of Meeting via...

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78 FR 71619 - Medicare and Medicaid Programs; Continued Approval of American Osteopathic Association/Healthcare...

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2013-11-29

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Medicare & Medicaid Services [CMS-3285-FN] Medicare and Medicaid Programs; Continued Approval of American Osteopathic Association/Healthcare... Medicare & Medicaid Services, HHS. ACTION: Final notice. SUMMARY: This final notice announces our decision...

76 FR 10905 - Agency Information Collection Activities: Proposed Collection; Comment Request

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2013-02-21

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention National Institute for Occupational Safety and Health Personal Protective Technology for Pesticide Handlers... for Disease Control and Prevention (CDC), Department of Health and Human Services (HHS). ACTION...

76 FR 36539 - Scientific Information Request on Insulin Delivery and Glucose Monitoring Devices for Diabetes...

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2011-06-22

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Scientific... for Healthcare Research and Quality (AHRQ), HHS. ACTION: Request for scientific information submissions. SUMMARY: The Agency for Healthcare Research and Quality (AHRQ) is seeking scientific information...

77 FR 60997 - Agency for Healthcare Research and Quality Agency Information Collection Activities: Proposed...

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2012-10-05

... care, including activities with respect to the quality, effectiveness, efficiency, appropriateness and... Information Collection Activities: Proposed Collection; Comment Request AGENCY: Agency for Healthcare Research and Quality, HHS. ACTION: Notice. SUMMARY: This notice announces the intention of the Agency for...

77 FR 58399 - Draft Guidance for Industry on Bioequivalence Recommendations for Pentosan Polysulfate Sodium...

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2012-09-20

... Polysulfate Sodium Capsule; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY... entitled ``Bioequivalence Recommendations for Pentosan Polysulfate Sodium.'' The recommendations provide... (ANDAs) for pentosan polysulfate sodium capsule. DATES: Although you can comment on any guidance at any...

76 FR 59142 - Guidance for Industry on Reproductive and Developmental Toxicities-Integrating Study Results To...

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2011-09-23

...--Integrating Study Results To Assess Concerns; Availability AGENCY: Food and Drug Administration, HHS. ACTION... industry entitled ``Reproductive and Developmental Toxicities--Integrating Study Results to Assess Concerns.'' This guidance describes an approach to estimating possible human developmental or reproductive risks...

78 FR 28223 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; OAA Title...

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2013-05-14

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Community Living Agency Information Collection Activities; Submission for OMB Review; Comment Request; OAA Title III-C Evaluation AGENCY: Administration for Community Living, HHS. ACTION: Notice. SUMMARY: The Administration for Community Living...

75 FR 42755 - The Negotiated Rulemaking Committee on the Designation of Medically Underserved Populations and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-22

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration The... Secretary of Health and Human Services, through the Administrator, Health Resources and Services... Professions Shortage Areas AGENCY: Health Resources and Services Administration (HRSA), HHS. ACTION: Notice of...

77 FR 38305 - Guidance for Industry on Lupus Nephritis Caused by Systemic Lupus Erythematosus-Developing...

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2012-06-27

... ``Lupus Nephritis Caused By Systemic Lupus Erythematosus--Developing Medical Products for Treatment...] Guidance for Industry on Lupus Nephritis Caused by Systemic Lupus Erythematosus--Developing Medical Products for Treatment; Withdrawal of Guidance AGENCY: Food and Drug Administration, HHS. ACTION: Notice...

10 CFR 1040.88 - Remedial and affirmative action by recipients.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Remedial and affirmative action by recipients. 1040.88... Standards for Determining Age Discrimination § 1040.88 Remedial and affirmative action by recipients. (a... take affirmative action to overcome the effects of conditions that resulted in limited participation in...

10 CFR 1040.88 - Remedial and affirmative action by recipients.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Remedial and affirmative action by recipients. 1040.88... Standards for Determining Age Discrimination § 1040.88 Remedial and affirmative action by recipients. (a... take affirmative action to overcome the effects of conditions that resulted in limited participation in...

Post-Operative Quality of Life in Children with Severe Perthes Disease: Differences to Matched Controls and Correlation with Clinical Function

PubMed Central

Palmen, Nina K.; Zilkens, Christoph; Rosenthal, Dietmar; Krauspe, Rüdiger; Hefter, Harald; Westhoff, Bettina

2014-01-01

The diagnosis of Legg-Calvé-Perthes disease (LCPD) has a considerable influence on the daily life of the patients with restrictions in their leisure time activities. This might influence their mood. Until now this aspect of the disease has been neglected. Therefore the objective of the study was to evaluate the health related quality of life (HRQoL) of children with severe LCPD who had an extensive surgery with pelvic/femoral osteotomy. The KIDSCREEN-10 and the modified Modified Harris Hip Score (mHHS) -questionnaire were administered to 17 children (16 boys and 1 girl) aged 5 to 11 years at the time of surgery. Analyses of mHHS were made preoperatively and at the time of the follow-up examination at least 2 years postoperatively. KIDSCREEN-analyses were made postoperatively. The follow-up results were compared to an age-matched normal control group. Correlations were computed between KIDSCREEN-10 and mHHS pre- and post-operatively. The postoperative calculated KIDSCREEN-10-T-value [70.2 (SD 12.7)] was higher than the mean T-value of the control-group [56.6 (SD 10.4)]. The mHHS improved from 54.4 (SD 19.9) to a score of 99.5 (SD 1.5) postoperatively. A strong correlation was found between the preoperative mHHS and the postoperative KIDSCREEN-10-T-value (Spearman’s-rho 0.67, P=0.003). After containment improving surgery and a mean follow-up period of 4.2 years the HRQoL-status is even better compared with a healthy age-matched control group. As well an excellent clinical function could be achieved. PMID:25568729

Hip Arthroscopy for Femoral-Acetabular Impingement: Do Active Claims Affect Outcomes?

PubMed

Gigi, Roy; Rath, Ehud; Sharfman, Zachary T; Shimonovich, Shachar; Ronen, Itai; Amar, Eyal

2016-04-01

To compare outcomes of 3 patient groups undergoing hip arthroscopy. This study included 138 consecutive hip arthroscopies (106 analyzed) for femoral-acetabular impingement (FAI) with or without labral tear in patients with a minimum 1-year follow-up. Inclusion criteria included patients older than 18 with clinical or radiologic manifestation of FAI with or without labral tear. Exclusion criteria included previous hip surgery and various hip pathologies. Patients were classified into 3 study groups. Group 1 included work-related injuries with active claims ACs (n = 33); mean age, 32 (range, 19 to 63); group 2 included sports injuries with no ACs (n = 35); mean age, 32 (range, 18 to 69); and group 3 included non-sports-related injuries without pending ACs (NAS; n = 38); mean age, 45 (range, 20 to 68). Outcomes were assessed using modified Harris hip scores (mHHS) and hip outcome scores (HOS) preoperatively and during the final evaluation. Baseline score for all groups did not significantly differ (P = .210 for mHHS, P = .176 for HOS). All groups significantly improved from preoperative to final evaluation (group 1: mHHS P = .42, HOS P = .001; group 2: mHHS P < .001, HOS P < .001; group 3 NAS: mHHS P = .001, HOS P = .007). AC patients had the lowest final evaluation scores, while the sports group had the highest. The NAS group did not differ from either group at final evaluation. Preoperative and final evaluation scores inversely correlated with age (r range, -24 to -28; P < .05). This study has shown that patients may benefit from arthroscopic repair of FAI and labral tears regardless of ACs. The level of improvement, however, is not constant across patients with different characteristics. Moreover, it appears that age may impact perceived improvement after hip arthroscopy. Hip arthroscopy as an intervention in patients with ACs provided positive outcomes, corroborating that an AC is not a contraindication for this procedure. Level III, retrospective comparative

77 FR 76049 - Draft Guidance for Industry on Electronic Source Data in Clinical Investigations; Correction

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2012-12-26

..., Office of Planning & Informatics, Center for Drug Evaluation and Research, Food and Drug Administration... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-D-0643...: Food and Drug Administration, HHS. ACTION: Notice; correction. [[Page 76050

77 FR 21573 - Government-Owned Inventions; Availability for Licensing

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2012-04-10

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Government-Owned Inventions; Availability for Licensing AGENCY: National Institutes of Health, Public Health Service, HHS. ACTION: Notice... the indicated licensing contact at the Office of Technology Transfer, National Institutes of Health...

76 FR 13193 - Government-Owned Inventions; Availability for Licensing

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78 FR 63211 - Privacy Act of 1974; Report of an Altered CMS System of Records Notice

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2013-10-23

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78 FR 57159 - Scientific Information Request on Medication Therapy Management

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2013-09-17

... Information Request on Medication Therapy Management AGENCY: Agency for Healthcare Research and Quality (AHRQ), HHS. ACTION: Request for scientific information submissions. SUMMARY: The Agency for Healthcare... therapy management Scientific information is being solicited to inform our review of Medication Therapy...

76 FR 40383 - National Institutes of Health

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2011-07-08

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75 FR 73110 - Health Center Program

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2010-11-29

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Health Center Program AGENCY: Health Resources and Services Administration, HHS. ACTION: Notice of Noncompetitive Replacement Awards to Upper Room AIDS Ministry, Inc. SUMMARY: The Health Resources and Services Administration...

75 FR 53701 - Health Center Program

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2010-09-01

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Health Center Program AGENCY: Health Resources and Services Administration, HHS. ACTION: Notice of Non-competitive Replacement Awards to Sunset Park Health Council, Inc. SUMMARY: The Health Resources and Services...

75 FR 32797 - Health Center Program

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2010-06-09

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78 FR 25457 - Health Center Program

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2013-05-01

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75 FR 74059 - Agency Information Collection Activities: Proposed Collection; Comment Request; Radioactive Drug...

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2010-11-30

... Committees AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug... regulation, and include studies of metabolism, human physiology, pathophysiology, or biochemistry. Section... consent required under the regulations. Each female research subject of childbearing potential must state...

78 FR 24756 - Government-Owned Inventions; Availability for Licensing

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2013-04-26

...; Availability for Licensing AGENCY: National Institutes of Health, Public Health Service, HHS. ACTION: Notice... chelators. Potential Commercial Applications: Cancer imaging. PET imaging. ImmunoPET. Competitive Advantages... crucial role in retinal physiology by forming a blood- retinal barrier and closely interacting with...

76 FR 35221 - Epidemiology Program for American Indian/Alaska Native Tribes and Urban Indian Communities...

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2011-06-16

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78 FR 22548 - Announcement of Requirements and Registration for “Apps4Tots Health Challenge”

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2013-04-16

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75 FR 53975 - Administration for Native Americans; Notice of Meeting

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2010-09-02

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78 FR 9054 - Issuance of Final Guidance Publication

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2013-02-07

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Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-24

...] Agency Information Collection Activities; Announcement of Office of Management and Budget Approval; Guidance for Industry on Pharmacogenomic Data Submissions AGENCY: Food and Drug Administration, HHS. ACTION... entitled ``Guidance for Industry on Pharmacogenomic Data Submissions'' has been approved by the Office of...

77 FR 22324 - Scientific Information Request on Treatment of Tinnitus

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-13

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Scientific Information Request on Treatment of Tinnitus AGENCY: Agency for Healthcare Research and Quality (AHRQ), HHS. ACTION: Request for scientific information submissions. SUMMARY: The Agency for Healthcare Research and...

77 FR 4043 - Scientific Information Request on the Use of Natriuretic Peptide Measurement in the Management of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-26

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Scientific...: Agency for Healthcare Research and Quality (AHRQ), HHS. ACTION: Request for scientific information submissions. SUMMARY: The Agency for Healthcare Research and Quality (AHRQ) is seeking scientific information...

75 FR 78709 - Public Comment on the Draft Tribal Consultation Policy

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-16

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Public Comment on the Draft Tribal Consultation Policy AGENCY: Administration for Children and Families, HHS. ACTION... that complement the Department- wide efforts. Since 2005, the Administration for Children and Families...

78 FR 77690 - Agency Information Collection Activities: Proposed Collection: Public Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-24

... Administration for Children and Families Agency Information Collection Activities: Proposed Collection: Public... Families, HHS. ACTION: Notice. SUMMARY: In compliance with the requirement for opportunity for public... Families (ACF) announce plans to submit an Information Collection Request (ICR), described below, to the...

77 FR 16551 - Early Retiree Reinsurance Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-21

...] Early Retiree Reinsurance Program AGENCY: Centers for Medicare & Medicaid Services (CMS), HHS. ACTION: Notice. SUMMARY: This notice establishes a timeframe by which plan sponsors participating in the Early... Early Retiree Reinsurance Program (ERRP) which provides reimbursement to eligible sponsors of employment...

77 FR 28252 - Oral Dosage Form New Animal Drugs; Change of Sponsor; Griseofulvin Powder; Levamisole...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-14

... Hydrochloride Powder; Oxytetracycline Powder AGENCY: Food and Drug Administration, HHS. ACTION: Final rule..., levamisole hydrochloride soluble powder, and oxytetracycline hydrochloride soluble powder from Teva Animal... Griseofulvin Powder, ANADAs 200-146 and 200-247 for Oxytetracycline Hydrochloride Soluble Powder, and ANADAs...

77 FR 56851 - Draft and Revised Draft Guidances for Industry Describing Product-Specific Bioequivalence...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-14

... Bioequivalence Recommendations; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY... draft product-specific bioequivalence (BE) recommendations. The recommendations provide product-specific guidance on the design of BE studies to support abbreviated new drug applications (ANDAs). In the Federal...

76 FR 12967 - Tribal Consultation Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-09

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Tribal Consultation Meetings AGENCY: Administration for Children and Families' Office of Head Start (OHS), HHS. ACTION... Services, Administration for Children and Families, OHS leadership, and the leadership of Tribal...

76 FR 20674 - Tribal Consultation Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-13

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Tribal Consultation Meetings AGENCY: Administration for Children and Families' Office of Head Start (OHS), HHS. ACTION... of Health and Human Services, Administration for Children and Families, Office of Head Start...

76 FR 57044 - Announcement of Requirements and Registration for “Ensuring Safe Transitions From Hospital to Home”

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-15

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Announcement of Requirements and Registration for... Coordinator for Health Information Technology, HHS. ACTION: Notice. SUMMARY: The ``Ensuring Safe Transitions... discharged patients to take charge of their health care during transitions of places of care. Innovative...

75 FR 39541 - Agency Information Collection Activities; Proposed Collection; Comment Request; “The Dairy...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-09

...'s Role in Residue Avoidance Survey'' AGENCY: Food and Drug Administration, HHS. ACTION: Notice... solicits comments on FDA's ``The Dairy Practitioner's Role in Residue Avoidance Survey.'' DATES: Submit... of information technology. ``The Dairy Practitioner's Role in Residue Avoidance Survey'' (OMB Control...

76 FR 65729 - Agency Information Collection Activities; Announcement of Office of Management and Budget...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-24

...; Temporary Marketing Permit Applications AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY... ``Temporary Marketing Permit Applications'' has been approved by the Office of Management and Budget (OMB... collection of information entitled ``Temporary Marketing Permit Applications'' to OMB for review and...

76 FR 33305 - Public Information Collection Requirements Submitted to the Office of Management and Budget (OMB...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-08

... Identifier: CMS-10379] Public Information Collection Requirements Submitted to the Office of Management and Budget (OMB); Correction AGENCY: Centers for Medicare & Medicaid Services (CMS), HHS. ACTION: Correction of notice. SUMMARY: This document corrects the information provided for [Document Identifier: CMS...

76 FR 13197 - National Institute of Environmental Health Sciences Strategic Planning

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-10

... understanding how the environment influences the development and progression of human disease. The NIEHS... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of... of Environmental Health Sciences (NIEHS), Department of Health and Human Services (HHS). ACTION...

78 FR 26638 - Non-Competitive One-Year Extension With Funds for Black Lung/Coal Miner Clinics Program (H37...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-07

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Non... AGENCY: Health Resources and Services Administration, HHS. ACTION: Correction. SUMMARY: The Health Resources and Services Administration published a notice in the Federal Register FR 2013-08482 (April 12...

78 FR 41412 - Advisory Commission of Childhood Vaccines; Request for Nominations for Voting Members

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-10

... Services Administration, HHS. ACTION: Notice. SUMMARY: The Health Resources and Services Administration... that result in fewer or no significant adverse reactions; surveying federal, state, and local programs... childhood vaccines, including the adverse reaction reporting requirements of section 2125(b); advising the...

76 FR 64228 - Draft Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-17

...: External Pacemaker Pulse Generator; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice... entitled ``Class II Special Controls Guidance Document: External Pacemaker Pulse Generator.'' This draft guidance document describes a means by which external pacemaker pulse generators may comply with the...

75 FR 29762 - HIT Policy Committee's Workgroup Meetings; Notice of Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-27

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of the National Coordinator for Health Information Technology HIT Policy Committee's Workgroup Meetings; Notice of Meetings AGENCY: Office of the National Coordinator for Health Information Technology, HHS. ACTION: Notice of meetings. This notice announces...

77 FR 5036 - Prospective Grant of Exclusive License: The Development of Human Anti-Mesothelin Monoclonal...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-01

... cancer, lung cancer, mesothelioma, and stomach/gastric cancer. The Licensed Field of Use explicitly... cancers, including mesothelioma, lung cancer, stomach/gastric cancer, ovarian cancer and pancreatic cancer... Cancers AGENCY: National Institutes of Health, Public Health Service, HHS. ACTION: Notice. SUMMARY: This...

76 FR 27335 - Laboratory Animal Welfare: Proposed Adoption and Implementation of the Eighth Edition of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-11

..., experimentation, biological testing, or related purposes) involving live vertebrate animals. The eighth edition of... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Laboratory Animal Welfare... Animals AGENCY: National Institutes of Health, HHS. ACTION: Notice of Additional Extension of Comment...

75 FR 62837 - Cooperative Agreement To Support Building Global Capacity for the Surveillance and Monitoring of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-13

... solutions through global collaboration and evidence-based approaches. C. Eligibility Information The.../Falsified Medicines and Supply Chain Threats AGENCY: Food and Drug Administration, HHS. ACTION: Notice... medicines and risks and breaches in the supply. FOR FURTHER INFORMATION AND ADDITIONAL REQUIREMENTS CONTACT...

75 FR 26759 - Health Care Integrity and Protection Data Bank (HIPDB) and National Practitioner Data Bank (NPDB...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-12

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Health Care... that license or certify health care practitioners, providers or suppliers, must report final adverse...-Compliant Government Agencies AGENCY: Health Resources and Services Administration, HHS. ACTION: Notice of...

Household Obesity Prevention: Take Action—a Group-Randomized Trial

PubMed Central

French, Simone A.; Gerlach, Anne F.; Mitchell, Nathan R.; Hannan, Peter J.; Welsh, Ericka M.

2018-01-01

The purpose of the present study was to evaluate an intervention to prevent weight gain among households (HHs) in the community. Ninety HHs were randomized to intervention or control group for 1 year. Intervention consisted of six face-to-face group sessions, placement of a television (TV) locking device on all home TVs, and home-based intervention activities. Measures were collected in person at baseline and 1 year. Weight, height, eating behaviors, physical activity (PA), and TV viewing were measured among HH members ages ≥12 years. Follow-up rate at 1 year was 96%. No significant intervention effects were observed for change in HH BMI-z score. Intervention HHs significantly reduced TV viewing, snacks/sweets intake, and dollars per person spent eating out, and increased (adults only) PA and self-weighing frequency compared with control HHs. A 1 year obesity prevention intervention targeting entire HHs was effective in reducing TV viewing, snack/sweets intake and eating out purchases. Innovative methods are needed to strengthen the home food environment intervention component. Longer intervention durations also need to be evaluated. PMID:21212771

Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA); interpretation of "federal public benefit"--HHS. Notice with comment period.

PubMed

1998-08-04

This notice with comment period interprets the term "Federal public benefit" as used in Title IV of the Personal Responsibility and Work Opportunity Reconciliation Act of 1996 (PRWORA), Pub. L. 104-193, and identifies the HHS programs that provide such benefits under this interpretation. According to section 401 if PRWORA, aliens who are not "qualified aliens" are not eligible for any "Federal public benefit," unless the "Federal public benefit" falls within a specified exception. A "Federal public benefit" includes "any grant, contract, loan, professional license, or commercial license" provided to an individual, and also "any retirement, welfare, health, disability, public or assisted housing, postsecondary education, food assistance, unemployment benefit, or any other similar benefit for which payments or assistance are provided to an individual, household, or family eligibility unit." Under section 432, providers of a non-exempt "Federal public benefit" must verify that a person applying for the benefit is a qualified alien and is eligible to receive the benefit. The HHS programs that provide "Federal public benefits" and are not otherwise excluded from the definition by the exceptions provided in section 401(b) are: Adoption Assistance Administration on Developmental Disabilities (ADD)-State Developmental Disabilities Councils (direct services only) ADD-Special Projects (direct services only) ADD-University Affiliated Programs (clinical disability assessment services only) Adult Programs/Payments to Territories Agency for Health Care Policy and Research Dissertation Grants Child Care and Development Fund Clinical Training Grant for Faculty Development in Alcohol & Drug Abuse Foster Care Health Profession Education and Training Assistance Independent Living Program Job Opportunities for Low Income Individuals (JOLI) Low Income Home Energy Assistance Program (LIHEAP) Medicare Medicaid (except assistance for an emergency medical condition) Mental Health Clinical

Action Planning in Typically and Atypically Developing Children (Unilateral Cerebral Palsy)

ERIC Educational Resources Information Center

Craje, Celine; Aarts, Pauline; Nijhuis-van der Sanden, Maria; Steenbergen, Bert

2010-01-01

In the present study, we investigated the development of action planning in children with unilateral Cerebral Palsy (CP, aged 3-6 years, n = 24) and an age matched control group. To investigate action planning, participants performed a sequential movement task. They had to grasp an object (a wooden play sword) and place the sword in a hole in a…

Action Prediction in Younger versus Older Adults: Neural Correlates of Motor Familiarity

PubMed Central

Diersch, Nadine; Mueller, Karsten; Cross, Emily S.; Stadler, Waltraud; Rieger, Martina; Schütz-Bosbach, Simone

2013-01-01

Generating predictions during action observation is essential for efficient navigation through our social environment. With age, the sensitivity in action prediction declines. In younger adults, the action observation network (AON), consisting of premotor, parietal and occipitotemporal cortices, has been implicated in transforming executed and observed actions into a common code. Much less is known about age-related changes in the neural representation of observed actions. Using fMRI, the present study measured brain activity in younger and older adults during the prediction of temporarily occluded actions (figure skating elements and simple movement exercises). All participants were highly familiar with the movement exercises whereas only some participants were experienced figure skaters. With respect to the AON, the results confirm that this network was preferentially engaged for the more familiar movement exercises. Compared to younger adults, older adults recruited visual regions to perform the task and, additionally, the hippocampus and caudate when the observed actions were familiar to them. Thus, instead of effectively exploiting the sensorimotor matching properties of the AON, older adults seemed to rely predominantly on the visual dynamics of the observed actions to perform the task. Our data further suggest that the caudate played an important role during the prediction of the less familiar figure skating elements in better-performing groups. Together, these findings show that action prediction engages a distributed network in the brain, which is modulated by the content of the observed actions and the age and experience of the observer. PMID:23704980

Action prediction in younger versus older adults: neural correlates of motor familiarity.

PubMed

Diersch, Nadine; Mueller, Karsten; Cross, Emily S; Stadler, Waltraud; Rieger, Martina; Schütz-Bosbach, Simone

2013-01-01

Generating predictions during action observation is essential for efficient navigation through our social environment. With age, the sensitivity in action prediction declines. In younger adults, the action observation network (AON), consisting of premotor, parietal and occipitotemporal cortices, has been implicated in transforming executed and observed actions into a common code. Much less is known about age-related changes in the neural representation of observed actions. Using fMRI, the present study measured brain activity in younger and older adults during the prediction of temporarily occluded actions (figure skating elements and simple movement exercises). All participants were highly familiar with the movement exercises whereas only some participants were experienced figure skaters. With respect to the AON, the results confirm that this network was preferentially engaged for the more familiar movement exercises. Compared to younger adults, older adults recruited visual regions to perform the task and, additionally, the hippocampus and caudate when the observed actions were familiar to them. Thus, instead of effectively exploiting the sensorimotor matching properties of the AON, older adults seemed to rely predominantly on the visual dynamics of the observed actions to perform the task. Our data further suggest that the caudate played an important role during the prediction of the less familiar figure skating elements in better-performing groups. Together, these findings show that action prediction engages a distributed network in the brain, which is modulated by the content of the observed actions and the age and experience of the observer.

Children Show Heightened Memory for Threatening Social Actions

ERIC Educational Resources Information Center

Baltazar, Nicole C.; Shutts, Kristin; Kinzler, Katherine D.

2012-01-01

Three experiments investigated whether a negativity bias in social perception extends to preschool-aged children's memory for the details of others' social actions and experiences. After learning about individuals who committed nice or mean social actions, children in Experiment 1 were more accurate at remembering who was mean compared with who…

Action anticipation in human infants reveals assumptions about anteroposterior body-structure and action.

PubMed

Hernik, Mikolaj; Fearon, Pasco; Csibra, Gergely

2014-04-22

Animal actions are almost universally constrained by the bilateral body-plan. For example, the direction of travel tends to be constrained by the orientation of the animal's anteroposterior axis. Hence, an animal's behaviour can reliably guide the identification of its front and back, and its orientation can reliably guide action prediction. We examine the hypothesis that the evolutionarily ancient relation between anteroposterior body-structure and behaviour guides our cognitive processing of agents and their actions. In a series of studies, we demonstrate that, after limited exposure, human infants as young as six months of age spontaneously encode a novel agent as having a certain axial direction with respect to its actions and rely on it when anticipating the agent's further behaviour. We found that such encoding is restricted to objects exhibiting cues of agency and does not depend on generalization from features of familiar animals. Our research offers a new tool for investigating the perception of animate agency and supports the proposal that the underlying cognitive mechanisms have been shaped by basic biological adaptations in humans.

Automatic imitation effects are influenced by experience of synchronous action in children.

PubMed

O'Sullivan, Eoin P; Bijvoet-van den Berg, Simone; Caldwell, Christine A

2018-07-01

By their fourth year of life, children are expert imitators, but it is unclear how this ability develops. One approach suggests that certain types of experience might forge associations between the sensory and motor representations of an action that may facilitate imitation at a later time. Sensorimotor experience of this sort may occur when an infant's action is imitated by a caregiver or when socially synchronous action occurs. This learning approach, therefore, predicts that the strength of sensory-motor associations should depend on the frequency and quality of previous experience. Here, we tested this prediction by examining automatic imitation, that is, the tendency of an action stimulus to facilitate the performance of that action and interfere with the performance of an incompatible action. We required children (aged between 3 years 8 months and 7 years 11 months) to respond to actions performed by an experimenter (e.g., two hands clapping) with both compatible actions (i.e., two hands clapping) and incompatible actions (i.e., two hands waving) at different stages in the experimental procedure. As predicted by a learning account, actions thought to be performed in synchrony (i.e., clapping/waving) produced stronger automatic imitation effects when compared with actions where previous sensorimotor experience is likely to be more limited (e.g., pointing/hand closing). Furthermore, these automatic imitation effects were not found to vary with age, with both compatible and incompatible responses quickening with age. These findings suggest a role for sensorimotor experience in the development of imitative ability. Copyright © 2018 Elsevier Inc. All rights reserved.

Neural correlates of action perception at the onset of functional grasping

PubMed Central

Daum, Moritz M.; Handl, Andrea; Gredebäck, Gustaf

2015-01-01

Event-related potentials were recorded while infants observe congruent or incongruent grasping actions at the age when organized grasping first emerges (4–6 months of age). We demonstrate that the event-related potential component P400 encodes the congruency of power grasps at the age of 6 months (Experiment 1) and in 5-month-old infants that have developed the ability to use power grasps (Experiment 2). This effect does not extend to precision grasps, which infants cannot perform (Experiment 3). Our findings suggest that infants’ encoding of the relationship between an object and a grasping hand (the action–perception link) is highly specialized to actions and manual configurations of actions that infants are able to perform. PMID:25193947

76 FR 55067 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-06

... Pharmaceutical Current Good Manufacturing Practice AGENCY: Food and Drug Administration, HHS. ACTION: Notice... Good Manufacturing Practice--(OMB Control Number 0910-0563)--Extension The guidance is intended to... products, on how to resolve disputes of scientific and technical issues relating to current good...

75 FR 42103 - Advancing the Development of Medical Products Used In the Prevention, Diagnosis, and Treatment of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-20

... Tropical Diseases; Public Hearing AGENCY: Food and Drug Administration, HHS. ACTION: Notice of public... hearing to solicit general views and information from interested persons on issues related to advancing... prevention, diagnosis, and treatment of neglected tropical diseases. In particular, FDA is seeking these...

76 FR 41501 - Notice of Intent To Award Affordable Care Act (ACA) Funding, EH09-907

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-14

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Notice of... Prevention (CDC), Department of Health and Human Services (HHS). ACTION: Notice. SUMMARY: This notice... in their FY 2011 applications submitted under funding opportunity EH09-907, ``National Environmental...

77 FR 43843 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-26

... Request; Financial Disclosure by Clinical Investigators AGENCY: Food and Drug Administration, HHS. ACTION... that written comments be faxed to the Office of Information and Regulatory Affairs, OMB, Attn: FDA Desk... Disclosure by Clinical Investigators--(OMB Control Number 0910-0396)--Extension Respondents to this...

76 FR 79701 - Bristol-Myers Squibb Co. et al.; Withdrawal of Approval of 70 New Drug Applications and 97...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-22

...: Florine Purdie, Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2011-N-0411... Drug Applications; Correction AGENCY: Food and Drug Administration, HHS. ACTION: Notice; correction...

76 FR 64951 - Apothecon et al.; Withdrawal of Approval of 103 New Drug Applications and 35 Abbreviated New Drug...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-19

... INFORMATION CONTACT: Florine Purdie, Center for Drug Evaluation and Research, Food and Drug Administration... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2009-N-0026... Applications; Correction AGENCY: Food and Drug Administration, HHS. ACTION: Notice; correction. SUMMARY: The...

78 FR 14557 - Guidance for Industry and Food and Drug Administration Staff: Investigational Device Exemption...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-06

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2009-D-0010] Guidance for Industry and Food and Drug Administration Staff: Investigational Device Exemption Guidance for Retinal Prostheses; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The...

75 FR 39697 - Indians Into Psychology Program; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-12

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Indian Health Service Indians Into Psychology Program; Correction AGENCY: Indian Health Service, HHS. ACTION: Notice correction. SUMMARY: The Indian Health Service...-IHS-2010-INPSY-0001, for the Indians Into Psychology Program. The document contained an incorrect...

78 FR 11892 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-20

..., color additive petitions, requests from exemption from regulation as a food additive, and submission of... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-N-0961... Request; Environmental Impact Considerations AGENCY: Food and Drug Administration, HHS. ACTION: Notice...

78 FR 19271 - Draft Guidance for Industry on Bioequivalence Recommendations for Metronidazole Vaginal Gel...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-29

... Metronidazole Vaginal Gel; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The... entitled ``Bioequivalence Recommendations for Metronidazole Vaginal Gel.'' The guidance provides specific...) for metronidazole vaginal gel. DATES: Although you can comment on any guidance at any time (see 21 CFR...

78 FR 5813 - 2013 Assuring Radiation Protection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-28

...] 2013 Assuring Radiation Protection AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY... of the Center for Devices and Radiological Health (CDRH) radiation protection program. The goal of the 2013 Assuring Radiation Protection will be to coordinate Federal, State, and Tribal activities to...

78 FR 26781 - Administration for Native Americans Tribal Consultation; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-08

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Administration... Families, Department of Health and Human Services. ACTION: Notice of tribal consultation. SUMMARY: The Department of Health and Human Services (HHS), Administration for Children and Families (ACF) will host a...

78 FR 44124 - Agency Information Collection Activities: Proposed Collection; Comment Request; Format and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-23

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0823] Agency Information Collection Activities: Proposed Collection; Comment Request; Format and Content Requirements for Over-the-Counter Drug Product Labeling AGENCY: Food and Drug Administration, HHS. ACTION...

75 FR 31448 - Agency Information Collection Activities; Proposed Collection; Comment Request; Format and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-03

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0248] Agency Information Collection Activities; Proposed Collection; Comment Request; Format and Content Requirements for Over-the-Counter Drug Product Labeling AGENCY: Food and Drug Administration, HHS. ACTION...

77 FR 8262 - Draft Guidance on Investigational New Drug Applications for Positron Emission Tomography Drugs...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-14

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2012-D-0081] Draft Guidance on Investigational New Drug Applications for Positron Emission Tomography Drugs; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug...

75 FR 5333 - Endocrinologic and Metabolic Drugs Advisory Committee; Cancellation

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-02

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0001] Endocrinologic and Metabolic Drugs Advisory Committee; Cancellation AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The meeting of the Endocrinologic and Metabolic Drugs Advisory Committee...

75 FR 36101 - Dermatologic and Ophthalmic Drugs Advisory Committee; Cancellation

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-24

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2010-N-0001] Dermatologic and Ophthalmic Drugs Advisory Committee; Cancellation AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The meeting of the Dermatologic and Ophthalmic Drugs Advisory Committee...

75 FR 70009 - Development of Health Risk Assessment Guidance

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-16

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Development of Health Risk Assessment Guidance AGENCY: Centers for Disease Control and Prevention (CDC), Department of Health and Human Services (HHS). ACTION: Request for Information. SUMMARY: The Centers for Disease...

78 FR 61362 - Agency for Healthcare Research and Quality

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-03

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Notice of Meetings AGENCY: Agency for Healthcare Research and Quality (AHRQ), HHS. ACTION: Notice of Five AHRQ Subcommittee Meetings. SUMMARY: The subcommittees listed below are part of AHRQ's Health Services Research...

75 FR 17938 - Privacy Act of 1974; Deletion of an Existing System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-08

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Privacy Act of 1974; Deletion of an Existing System of Records AGENCY: Department of Health and Human Services (HHS), Health Resources and Services Administration (HRSA). ACTION: Notice to delete an existing system...

75 FR 17937 - Privacy Act of 1974; Deletion of an Existing System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-08

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Privacy Act of 1974; Deletion of an Existing System of Records AGENCY: Department of Health and Human Services (HHS), Health Resources and Services Administration (HRSA). ACTION: Notice to delete an existing HRSA...

78 FR 69696 - Agency Information Collection Activities: Submission to OMB for Review and Approval; Public...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-20

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Health Resources and Services Administration Agency...: Health Resources and Services Administration, HHS. ACTION: Notice. SUMMARY: In compliance with Section 3507(a)(1)(D) of the Paperwork Reduction Act of 1995, the Health Resources and Services Administration...

76 FR 58812 - Patient Safety Organizations: Delisting for Cause of Patient Safety Organization One, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-22

... Organizations: Delisting for Cause of Patient Safety Organization One, Inc. AGENCY: Agency for Healthcare Research and Quality (AHRQ), HHS. ACTION: Notice of Delisting. SUMMARY: Patient Safety Organization One, Inc.: AHRQ has delisted Patient Safety Organization One, Inc. as a Patient Safety Organization (PSO...

76 FR 11786 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-03

... Request; Radioactive Drug Research Committees AGENCY: Food and Drug Administration, HHS. ACTION: Notice... metabolism, human physiology, pathophysiology, or biochemistry. Section 361.1(c)(2) requires that each.... Each female research subject of childbearing potential must state in writing that she is not pregnant...

75 FR 28622 - FDA Transparency Initiative: Draft Proposals for Public Comment Regarding Disclosure Policies of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-21

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2009-N-0247] FDA Transparency Initiative: Draft Proposals for Public Comment Regarding Disclosure Policies of the U.S. Food and Drug Administration; Availability AGENCY: Food and Drug Administration, HHS. ACTION...