Sample records for agua pressurizada integral

  1. 2. William Beardsley standing along the Agua Fria River near ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. William Beardsley standing along the Agua Fria River near construction site of the Agua Fria project. Photographer James Dix Schuyler, 1903. Source: Schuyler, James D. 'Report on the Water Supply of the Agua Fria River, and the Storage Reservoir Project of the Agua Fria Water and Land Company For Irrigation in the Gila River Valley, Arizona,' (September 29, 1903). Arizona Historical Collection, Hayden Library, Arizona State University, Tempe, Arizona. (Typewritten.) - Waddell Dam, On Agua Fria River, 35 miles northwest of Phoenix, Phoenix, Maricopa County, AZ

  2. 7. Photocopy of map of the Agua Fria Valley and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photocopy of map of the Agua Fria Valley and lands to be irrigated by the Agua Fria Water and Land Company. Photographer Mark Durben, 1987 Source: 'Map of the Agua Fria Valley and the Western Portion of the Salt River Valley Showing the System of Reservoirs and Canals of the Agua Fria Water and Land Company and the Land to be Irrigated Thereby 160,000 Acres of New Land to be Reclaimed in the Maricopa County, Arizona Territory,' (Brochure) Union Photo Engraving Company, c. 1895, Salt River Project Research Archives, Tempe, Arizona. - Waddell Dam, On Agua Fria River, 35 miles northwest of Phoenix, Phoenix, Maricopa County, AZ

  3. 72. Headgates for Agua Fria project canal on east end ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    72. Headgates for Agua Fria project canal on east end of diversion dam. Photographer Mark Durben. Source: Salt River Project. - Waddell Dam, On Agua Fria River, 35 miles northwest of Phoenix, Phoenix, Maricopa County, AZ

  4. 54. Downstream face of Agua Fria project's diversion dam showing ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    54. Downstream face of Agua Fria project's diversion dam showing initial masonry construction and poured concrete capping. Photographer Mark Durben, 1986. Source: Salt River Project. - Waddell Dam, On Agua Fria River, 35 miles northwest of Phoenix, Phoenix, Maricopa County, AZ

  5. Integrated measures for preservation, restoration and improvement of the environmental conditions of the Lagoon Olho d'Agua basin.

    PubMed

    Florencio, L; Kato, M T; de Lima, E S

    2001-06-01

    The Lagoon Olho d'Agua in Pernambuco State, Northeast Brazil has received increasing environmental concern due to significant stress from pollution in the catchment. The existing environmental problems are the result of great pressure from a broad range of human activities, especially in the last 10 years. Serious pollution exists mainly from some industrial and urban activities, which increased intensively after the eighties. There is a strong social and economical pressure for housing and construction near the lagoon, due to the available land nearby beaches and estuarine zone, and recently by growing tourism activities. Uncontrolled land use by low-income communities and the pressure for construction by developers have led to landfilling and to deterioration of water quality in the lagoon catchment. Improvement of the environmental conditions in the catchment needs integrated measures. Guidelines and some specific actions involving several institutions have been established and refer to sanitation and urban infrastructure as the main priorities. A main target is the construction of low-cost sewage system with smaller and decentralised treatment plants.

  6. Regulation of the alpha-glucuronidase-encoding gene ( aguA) from Aspergillus niger.

    PubMed

    de Vries, R P; van de Vondervoort, P J I; Hendriks, L; van de Belt, M; Visser, J

    2002-09-01

    The alpha-glucuronidase gene aguA from Aspergillus niger was cloned and characterised. Analysis of the promoter region of aguA revealed the presence of four putative binding sites for the major carbon catabolite repressor protein CREA and one putative binding site for the transcriptional activator XLNR. In addition, a sequence motif was detected which differed only in the last nucleotide from the XLNR consensus site. A construct in which part of the aguA coding region was deleted still resulted in production of a stable mRNA upon transformation of A. niger. The putative XLNR binding sites and two of the putative CREA binding sites were mutated individually in this construct and the effects on expression were examined in A. niger transformants. Northern analysis of the transformants revealed that the consensus XLNR site is not actually functional in the aguA promoter, whereas the sequence that diverges from the consensus at a single position is functional. This indicates that XLNR is also able to bind to the sequence GGCTAG, and the XLNR binding site consensus should therefore be changed to GGCTAR. Both CREA sites are functional, indicating that CREA has a strong influence on aguA expression. A detailed expression analysis of aguA in four genetic backgrounds revealed a second regulatory system involved in activation of aguA gene expression. This system responds to the presence of glucuronic and galacturonic acids, and is not dependent on XLNR.

  7. Agua Caliente and Their Music.

    ERIC Educational Resources Information Center

    Ryterband, Roman

    1979-01-01

    Discusses the traditional music of the Agua Caliente band of California's Desert Cahuilla Indian tribe, including accompanying instruments, types of songs, thematic material, and performance routines. Exploring the structure of the music, the article describes meter, tempo, harmony and tonal gravitations, and use of words. (DS)

  8. Geologie study off gravels of the Agua Fria River, Phoenix, AZ

    USGS Publications Warehouse

    Langer, W.H.; Dewitt, E.; Adams, D.T.; O'Briens, T.

    2010-01-01

    The annual consumption of sand and gravel aggregate in 2006 in the Phoenix, AZ metropolitan area was about 76 Mt (84 million st) (USGS, 2009), or about 18 t (20 st) per capita. Quaternary alluvial deposits in the modern stream channel of the Agua Fria River west of Phoenix are mined and processed to provide some of this aggregate to the greater Phoenix area. The Agua Fria drainage basin (Fig. 1) is characterized by rugged mountains with high elevations and steep stream gradients in the north, and by broad alluvial filled basins separated by elongated faultblock mountain ranges in the south. The Agua Fria River, the basin’s main drainage, flows south from Prescott, AZ and west of Phoenix to the Gila River. The Waddel Dam impounds Lake Pleasant and greatly limits the flow of the Agua Fria River south of the lake. The southern portion of the watershed, south of Lake Pleasant, opens out into a broad valley where the river flows through urban and agricultural lands to its confluence with the Gila River, a tributary of the Colorado River.

  9. [Water birds from Agua Dulce lake and El Ermitaño estuary, Jalisco, Mexico].

    PubMed

    Hernández Vázquez, Salvador

    2005-01-01

    Waterbird abundance, and seasonal and spatial distribution, were studied in two natural water pools at Jalisco, Mexico, from December 1997 through November 1998. Maximum monthly abundance in Agua Dulce lake and El Ermitaño estuary was 86 471 birds (29 686 in Agua Dulce and 56 785 in Ermitaño), with a total cummulative abundance of 179 808 individuals (66 976 in Agua Dulce and 112 832 in Ermitaño). A total of 87 waterbirds species were recorded, 78 in Agua Dulce and 73 in Ermitaño. The higher species richness and abundance was observed during winter, when migratory species arrived. Most species prefered shallow waters, except seabirds which prefered protected areas such as dunes in Agua Dulce. Other groups, like clucks and related species. prefered low salinity areas, for example in the south-east area of Ermitaño. The higher abundance of the shorehirds was found when the water level on the estuary was low. Herons were seen often at areas with high salinity and influenced by tides (e.g. mouth of Ermitaño).

  10. Informe: Agua potable - la EPA necesita adoptar medidas adicionales para garantizar que los pequeños sistemas de agua comunitarios señalados como graves infractores logren cumplir con las normas

    EPA Pesticide Factsheets

    Informe #16-P-0108, 22 de Marzo de 2016. La EPA puede proteger mejor al público del agua potable contaminada, lo que incluye a casi 200,000 personas en Puerto Rico que todavía carecen de agua potable segura.

  11. 75 FR 21034 - Notice of Availability of Record of Decision for the Agua Fria National Monument and Bradshaw...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-22

    ....241A] Notice of Availability of Record of Decision for the Agua Fria National Monument and Bradshaw... availability of the Record of Decision (ROD)/Approved Resource Management Plan (RMP) for the Agua Fria National... of the planning area during prehistoric or historic times. The Agua Fria National Monument includes...

  12. The source, discharge, and chemical characteristics of water from Agua Caliente Spring, Palm Springs, California

    USGS Publications Warehouse

    Brandt, Justin; Catchings, Rufus D.; Christensen, Allen H.; Flint, Alan L.; Gandhok, Gini; Goldman, Mark R.; Halford, Keith J.; Langenheim, V.E.; Martin, Peter; Rymer, Michael J.; Schroeder, Roy A.; Smith, Gregory A.; Sneed, Michelle; Martin, Peter

    2011-01-01

    Agua Caliente Spring, in downtown Palm Springs, California, has been used for recreation and medicinal therapy for hundreds of years and currently (2008) is the source of hot water for the Spa Resort owned by the Agua Caliente Band of the Cahuilla Indians. The Agua Caliente Spring is located about 1,500 feet east of the eastern front of the San Jacinto Mountains on the southeast-sloping alluvial plain of the Coachella Valley. The objectives of this study were to (1) define the geologic structure associated with the Agua Caliente Spring; (2) define the source(s), and possibly the age(s), of water discharged by the spring; (3) ascertain the seasonal and longer-term variability of the natural discharge, water temperature, and chemical characteristics of the spring water; (4) evaluate whether water-level declines in the regional aquifer will influence the temperature of the spring discharge; and, (5) estimate the quantity of spring water that leaks out of the water-collector tank at the spring orifice.

  13. The Agua Salud Project, Central Panama

    NASA Astrophysics Data System (ADS)

    Stallard, R. F.; Elsenbeer, H.; Ogden, F. L.; Hall, J. S.

    2007-12-01

    The Agua Salud Project utilizes the Panama Canal's central role in world commerce to focus global attention on the ecosystem services provided by tropical forests. It will be the largest field experiment of its kind in the tropics aimed at quantifying the environmental services (water, carbon, and biodiversity) provided by tropical forests. The Agua Salud Watershed is our principal field site. This watershed and the headwaters of several adjacent rivers include both protected mature forests and a wide variety of land uses that are typical of rural Panama. Experiments at the scale of entire catchments will permit complete water and carbon inventories and exchanges for different landscape uses. The following questions will be addressed: (1) How do landscape treatments and management approaches affect ecosystem services such as carbon storage, water quality and quantity, dry- season water supply, and biodiversity? (2) Can management techniques be designed to optimize forest production along with ecosystem services during reforestation? (3) Do different tree planting treatments and landscape management approaches influence groundwater storage, which is thought to be critical to maintaining dry-season flow, thus insuring the full operation of the Canal during periods of reduced rainfall and severe climatic events such as El Niño. In addition we anticipate expanding this project to address biodiversity, social, and economic values of these forests.

  14. AGUA TIBIA PRIMITIVE AREA, CALIFORNIA.

    USGS Publications Warehouse

    Irwin, William P.; Thurber, Horace K.

    1984-01-01

    The Agua Tibia Primitive Area in southwestern California is underlain by igneous and metamorphic rocks that are siilar to those widely exposed throughout much of the Peninsular Ranges. To detect the presence of any concealed mineral deposits, samples of stream sediments were collected along the various creeks that head in the mountain. As an additional aid in evaluating the mineral potential, an aeromagnetic survey was made and interpreted. A search for records of past or existing mining claims within the primitive area was made but none was found. Evidence of deposits of metallic or nonmetallic minerals was not seen during the study.

  15. Agua Caliente Solar Feasibility and Pre-Development Study Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carolyn T. Stewart, Managing Partner; Red Mountain Energy Partners

    2011-04-26

    Evaluation of facility- and commercial-scale solar energy projects on the Agua Caliente Band of Cahuilla Indians Reservation in Palm Springs, CA. The Agua Caliente Band of Cahuilla Indians (ACBCI) conducted a feasibility and pre-development study of potential solar projects on its lands in southern California. As described below, this study as a logical and necessary next step for ACBCI. Support for solar project development in California, provided through the statewide California Solar Initiative (CSI), its Renewable Portfolio Standard and Feed-in Tariff Program, and recently announced Reverse Auction Mechanism, provide unprecedented support and incentives that can be utilized by customers ofmore » California's investor-owned utilities. Department of Energy (DOE) Tribal Energy Program funding allowed ACBCI to complete its next logical step to implement its Strategic Energy Plan, consistent with its energy and sustainability goals.« less

  16. SEISMIC STUDY OF THE AGUA DE PAU GEOTHERMAL PROSPECT, SAO MIGUEL, AZORES.

    USGS Publications Warehouse

    Dawson, Phillip B.; Rodrigues da Silva, Antonio; Iyer, H.M.; Evans, John R.

    1985-01-01

    A 16 station array was operated over the 200 km**2 central portion of Sao Miguel utilizing 8 permanent Instituto Nacional de Meterologia e Geofisica stations and 8 USGS portable stations. Forty four local events with well constrained solutions and 15 regional events were located. In addition, hundreds of unlocatable seismic events were recorded. The most interesting seismic activity occurred in a swarm on September 6 and 7, 1983 when over 200 events were recorded in a 16 hour period. The seismic activity around Agua de Pau was centered on the east and northeast slopes of the volcano. The data suggest a boiling hydrothermal system beneath the Agua de Pau volcano, consistent with a variety of other data.

  17. Use of Archival Sources to Improve Water-Related Hazard Assessments at Volcán de Agua, Guatemala

    NASA Astrophysics Data System (ADS)

    Hutchison, A. A.; Cashman, K. V.; Rust, A.; Williams, C. A.

    2013-12-01

    This interdisciplinary study focuses on the use of archival sources from the 18th Century Spanish Empire to develop a greater understanding of mudflow trigger mechanisms at Volcán de Agua in Guatemala. Currently, hazard assessments of debris flows at Volcán de Agua are largely based on studies of analogous events, such as the mudflow at Casita Volcano in 1998 caused by excessive rainfall generated by Hurricane Mitch. A preliminary investigation of Spanish archival sources, however, indicates that a damaging mudflow from the volcano in 1717 may have been triggered by activity at the neighbouring Volcán de Fuego. A VEI 4 eruption of Fuego in late August 1717 was followed by 33 days of localized 'retumbos' and then a major local earthquake with accompanying mudflows from several 'bocas' on the southwest flank of Agua. Of particular importance for this study is an archival source from Archivos Generales de Centro América (AGCA) that consists of a series of letters, petitions and witness statements that were written and gathered following the catastrophic events of 1717. Their purpose was to argue for royal permission to relocate the capital city, which at the time was located on the lower flanks of Volcán de Agua. Within these documents there are accounts of steaming 'avenidas' of water with sulphurous smells, and quantitative descriptions that suggest fissure formation related to volcanic activity at Volcán de Fuego. Clear evidence for volcano-tectonic activity at the time, combined with the fact there is no mention of rainfall in the documents, suggest that outbursts of mud from Agua's south flank may have been caused by a volcanic perturbation of a hydrothermal system. This single example suggests that further analysis of archival documents will provide a more accurate and robust assessment of water related hazards at Volcán de Agua than currently exists.

  18. Flood of February 1980 along the Agua Fria River, Maricopa County, Arizona

    USGS Publications Warehouse

    Thomsen, B.W.

    1980-01-01

    The flood of February 20, 1980, along the Agua Fria River below Waddell Dam, Maricopa County, Ariz., was caused by heavy rains during February 13-20. The runoff filled Lake Pleasant and resulted in the largest release--66,600 cubic feet per second--from the reservoir since it was built in 1927; the maximum inflow to the reservoir was about 73,300 cubic feet per second. The area inundated by the releases includes about 28 miles along the channel from the mouth of the Agua Fria River to the Beardsley Canal flume crossing 5 miles downstream from Waddell Dam. The flood of 1980 into Lake Pleasant has a recurrence interval of about 47 years, whereas the flood of record (1919) has a recurrence interval of about 100 years. (USGS)

  19. Avisos de salud sobre el PFOA y PFOS en el agua potable

    EPA Pesticide Factsheets

    La EPA estableció avisos de salud sobre el ácido perfluorooctanoico (PFOA) y el sulfonato de perfluorooctano (PFOS) para proporcionar información a los operadores de sistemas de agua potable y funcionarios estatales, tribales y locales sobre los riesgos de

  20. Hydrologic characteristics of the Agua Fria National Monument, central Arizona, determined from the reconnaissance study

    USGS Publications Warehouse

    Fleming, John B.

    2005-01-01

    Hydrologic conditions in the newly created Agua Fria National Monument were characterized on the basis of existing hydrologic and geologic information, and streamflow data collected in May 2002. The study results are intended to support the Bureau of Land Management's future water-resource management responsibilities, including quantification of a Federal reserved water right within the monument. This report presents the study results, identifies data deficiencies, and describes specific approaches for consideration in future studies. Within the Agua Fria National Monument, the Agua Fria River flows generally from north to south, traversing almost the entire 23-mile length of the monument. Streamflow has been measured continuously at a site near the northern boundary of the monument since 1940. Streamflow statistics for this site, and streamflow measurements from other sites along the Agua Fria River, indicate that the river is perennial in the northern part of the monument but generally is intermittent in downstream reaches. The principal controls on streamflow along the river within the monument appear to be geology, the occurrence and distribution of alluvium, inflow at the northern boundary and from tributary canyons, precipitation, and evapotranspiration. At present, (2004) there is no consistent surface-water quality monitoring program being implemented for the monument. Ground-water recharge within the monument likely results from surface-water losses and direct infiltration of precipitation. Wells are most numerous in the Cordes Junction and Black Canyon City areas. Only eight wells are within the monument. Ground-water quality data for wells in the monument area consist of specific-conductance values and fluoride concentrations. During the study, ground-water quality data were available for only one well within the monument. No ground-water monitoring program is currently in place for the monument or surrounding areas.

  1. Lahar hazards at Agua volcano, Guatemala

    USGS Publications Warehouse

    Schilling, S.P.; Vallance, J.W.; Matías, O.; Howell, M.M.

    2001-01-01

    At 3760 m, Agua volcano towers more than 3500 m above the Pacific coastal plain to the south and 2000 m above the Guatemalan highlands to the north. The volcano is within 5 to 10 kilometers (km) of Antigua, Guatemala and several other large towns situated on its northern apron. These towns have a combined population of nearly 100,000. It is within about 20 km of Escuintla (population, ca. 100,000) to the south. Though the volcano has not been active in historical time, or about the last 500 years, it has the potential to produce debris flows (watery flows of mud, rock, and debris—also known as lahars when they occur on a volcano) that could inundate these nearby populated areas.

  2. HOJA INFORMATIVA Presencia de PFOA y PFOS en el agua potable Avisos de salud

    EPA Pesticide Factsheets

    La EPA estableció avisos de salud sobre el ácido perfluorooctanoico (PFOA) y el sulfonato de perfluorooctano (PFOS) para proporcionar información a los operadores de sistemas de agua potable y funcionarios estatales y locales para que puedan adoptar las me

  3. 76 FR 63614 - Agua Caliente Solar, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER12-21-000] Agua Caliente Solar, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for Blanket... Caliente Solar, LLC's application for market-based rate authority, with an accompanying rate tariff, noting...

  4. The Laramide Mesa formation and the Ojo de Agua caldera, southeast of the Cananea copper mining district, Sonora, Mexico

    USGS Publications Warehouse

    Cox, Dennis P.; Miller, Robert J.; Woodbourne, Keith L.

    2006-01-01

    The Mesa Formation extends from Cananea, Mexico, southeast to the Sonora River and is the main host rock of Laramide porphyry copper deposits in the Cananea District and at the Alacran porphyry prospect to the east. The Mesa consists of two members-a lower andesite and an upper dacite. The lowest part of the dacite member is a crystal tuff about 100 m thick. This tuff is the outfall of a caldera centered near the village of Ojo de Agua, dated by 40Ar/39Ar at 65.8 Ma ?0.4. The Ojo de Agua Caldera is about 9 km in diameter and is filled by a light gray biotite dacite tuff with abundant flattened pumice fragments. The volume of the caldera is estimated to be 24 km3.

  5. Chihuahuan desert flora of La Calera, Municipio de Agua Prieta, Sonora, Mexico

    Treesearch

    Ana Lilia Reina-Guerrero; Thomas R. Van Devender

    2013-01-01

    A total of 555 plant collections were made on 20 trips in 2002-2008 to La Calera area in the Sierra Anibácachi, Municipio de Agua Prieta, 11.3 km south of the Arizona border (31°13’59”N 109°37’53”W, elevation range from 1220 m to 1539 m) in northeastern Sonora. Chihuahuan desertscrub on limestone substrates is dominated by creosotebush (Larrrea divaricata), Chihuahuan...

  6. aguA, the gene encoding an extracellular alpha-glucuronidase from Aspergillus tubingensis, is specifically induced on xylose and not on glucuronic acid.

    PubMed

    de Vries, R P; Poulsen, C H; Madrid, S; Visser, J

    1998-01-01

    An extracellular alpha-glucuronidase was purified and characterized from a commercial Aspergillus preparation and from culture filtrate of Aspergillus tubingensis. The enzyme has a molecular mass of 107 kDa as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and 112 kDa as determined by mass spectrometry, has a determined pI just below 5.2, and is stable at pH 6.0 for prolonged times. The pH optimum for the enzyme is between 4.5 and 6.0, and the temperature optimum is 70 degrees C. The alpha-glucuronidase is active mainly on small substituted xylo-oligomers but is also able to release a small amount of 4-O-methylglucuronic acid from birchwood xylan. The enzyme acts synergistically with endoxylanases and beta-xylosidase in the hydrolysis of xylan. The enzyme is N glycosylated and contains 14 putative N-glycosylation sites. The gene encoding this alpha-glucuronidase (aguA) was cloned from A. tubingensis. It consists of an open reading frame of 2,523 bp and contains no introns. The gene codes for a protein of 841 amino acids, containing a eukaryotic signal sequence of 20 amino acids. The mature protein has a predicted molecular mass of 91,790 Da and a calculated pI of 5.13. Multiple copies of the gene were introduced in A. tubingensis, and expression was studied in a highly overproducing transformant. The aguA gene was expressed on xylose, xylobiose, and xylan, similarly to genes encoding endoxylanases, suggesting a coordinate regulation of expression of xylanases and alpha-glucuronidase. Glucuronic acid did not induce the expression of aguA and also did not modulate the expression on xylose. Addition of glucose prevented expression of aguA on xylan but only reduced the expression on xylose.

  7. aguA, the Gene Encoding an Extracellular α-Glucuronidase from Aspergillus tubingensis, Is Specifically Induced on Xylose and Not on Glucuronic Acid

    PubMed Central

    de Vries, Ronald P.; Poulsen, Charlotte H.; Madrid, Susan; Visser, Jaap

    1998-01-01

    An extracellular α-glucuronidase was purified and characterized from a commercial Aspergillus preparation and from culture filtrate of Aspergillus tubingensis. The enzyme has a molecular mass of 107 kDa as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and 112 kDa as determined by mass spectrometry, has a determined pI just below 5.2, and is stable at pH 6.0 for prolonged times. The pH optimum for the enzyme is between 4.5 and 6.0, and the temperature optimum is 70°C. The α-glucuronidase is active mainly on small substituted xylo-oligomers but is also able to release a small amount of 4-O-methylglucuronic acid from birchwood xylan. The enzyme acts synergistically with endoxylanases and β-xylosidase in the hydrolysis of xylan. The enzyme is N glycosylated and contains 14 putative N-glycosylation sites. The gene encoding this α-glucuronidase (aguA) was cloned from A. tubingensis. It consists of an open reading frame of 2,523 bp and contains no introns. The gene codes for a protein of 841 amino acids, containing a eukaryotic signal sequence of 20 amino acids. The mature protein has a predicted molecular mass of 91,790 Da and a calculated pI of 5.13. Multiple copies of the gene were introduced in A. tubingensis, and expression was studied in a highly overproducing transformant. The aguA gene was expressed on xylose, xylobiose, and xylan, similarly to genes encoding endoxylanases, suggesting a coordinate regulation of expression of xylanases and α-glucuronidase. Glucuronic acid did not induce the expression of aguA and also did not modulate the expression on xylose. Addition of glucose prevented expression of aguA on xylan but only reduced the expression on xylose. PMID:9440512

  8. [Active search for leprosy and other skin diseases in school children from Agua de Dios, Colombia].

    PubMed

    Rodríguez, Gerzaín; González, Rosalba; Gonzalez, Deysy; Granados, Carolina; Pinto, Rafael; Herrera, Hilda; Gutiérrez, Luisa F; Hernández, Elkin; López, Fernando; Gómez, Yenny

    2007-01-01

    Actively searching for leprosy, other skin diseases and BCG vaccination scars amongst school children from Agua de Dios, the municipality having the highest prevalence of leprosy in Colombia. A clinical examination of the children was carried out by nurses, interns, general practitioners and experts on leprosy. Skin smear tests and skin biopsies were performed when the clinical findings suggested leprosy. Anti-phenolic glycolipid antibodies in blood were determined in special cases. 86 % of the 2 844 school children were examined; 833 had skin diseases and 16 % of these required evaluation by specialists. Four new cases of paucibacillary leprosy, two indeterminate and two primary polyneuritic cases were found. Pediculosis capitis, pityriasis alba, tinea versicolor, hypopigmented nevus, insect bites and miliaria were frequently detected. BCG vaccination scars were absent in 387 children; following several logistical problems, they were vaccinated. Four children had signs of childhood abuse. An 11-year-old girl presented hypopigmented mycosis fungoides. All diseases and conditions found were treated. The community received information regarding the results, emphasising the importance of an early diagnosis of leprosy. The incidence of leprosy found (16/10,000) was 123 times higher than the rest of the country's incidence. It is advisable to continue clinical examinations in Agua de Dios and research into risk factors for acquiring leprosy.

  9. Vigilando la Calidad del Agua de los Grandes Rios de la Nacion: El Programa NASQAN del Rio Grande (Rio Bravo del Norte)

    USGS Publications Warehouse

    Lurry, Dee L.; Reutter, David C.; Wells, Frank C.; Rivera, M.C.; Munoz, A.

    1998-01-01

    La Oficina del Estudio Geologico de los Estados Unidos (U.S. Geological Survey, 0 USGS) ha monitoreado la calidad del agua de la cuenca del Rio Grande (Rio Bravo del Norte) desde 1995 como parte de la rediseiiada Red Nacional para Contabilizar la Calidad del Agua de los Rios (National Stream Quality Accounting Network, o NASOAN) (Hooper and others, 1997). EI programa NASOAN fue diseiiado para caracterizar las concentraciones y el transporte de sedimento y constituyentes quimicos seleccionados, encontrados en los grandes rios de los Estados Unidos - incluyendo el Misisipi, el Colorado y el Columbia, ademas del Rio Grande. En estas cuatro cuencas, el USGS opera actualmente (1998) una red de 40 puntos de muestreo pertenecientes a NASOAN, con un enfasis en cuantificar el flujo en masa (la cantidad de material que pasa por la estacion, expresado en toneladas por dial para cada constituyente. Aplicacando un enfoque consistente, basado en la cuantificacion de flujos en la cuenca del Rio Grande, el programa NASOAN esta generando la informacion necesaria para identificar fuentes regionales de diversos contaminantes, incluyendo sustancias qui micas agricolas y trazas elementos en la cuenca. EI efecto de las grandes reservas en el Rio Grande se puede observar segun los flujos de constituyentes discurren a 10 largo del rio. EI analisis de los flujos de constituyentes a escala de la cuenca proveera los medios para evaluar la influencia de la actividad humana sobre las condiciones de calidad del agua del Rio Grande.

  10. An Eco-hydrologic Assessment of Small Experimental Catchments with Various Land Uses within the Panama Canal Watershed: Agua Salud Project

    NASA Astrophysics Data System (ADS)

    Crouch, T. D.; Ogden, F. L.; Stallard, R. F.; Smithsonian Tropical Research Institute, Panama Canal Watershed Experiment, Agua Salud Project

    2010-12-01

    Hydrological processes in the humid tropics are poorly understood and an important topic when it comes to water management in the seasonal tropics. The Smithsonian Tropical Research Institute, Panama Canal Watershed Experiment, Agua Salud Project, seeks to understand these processes and quantify the long-term effects of different land cover and uses across the Panama Canal Watershed. One of the project’s main objectives is to understand how reforestation effects seasonal stream flows. To meet this objective, a baseline characterization of hydrology on the small catchment scale is being assessed across different land uses typical in rural Panama. The small experimental catchments are found within Panama’s protected Soberania National Park and the adjacent headwaters of the Agua Salud and Mendoza Rivers, all of which are part of the greater Panama Canal Watershed. The land uses being monitored include a variety of control catchments as well as treated pasture sites. The catchments used for this study include a mature old regrowth forest, a 50% deforested or mosaic regrowth site, an active pasture and a monoculture invasive grass site (saccharum spontaneum) as experimental controls and two treated catchments that were recently abandoned pastures converted to teak and native species timber plantations. Installed instrumentation includes a network of rain gauges, v-notched weirs, atmometers, an eddy covariance system and an assortment of meteorological and automated geochemical sampling systems. Spatial, rainfall, runoff and ET data across these six geologically and topographically similar catchments are available from 2009 and 2010. Classic water balance and paired catchment techniques were used to compare the catchments on an annual, seasonal, and event basis. This study sets the stage for hydrologic modeling and for better understanding the effects of vegetation and land-use history on rainfall-runoff processes for the Agua Salud Project and Panama Canal

  11. Integration of New Methods in Soils and Geomorphology Applied to Cultural Resources Management on Military Lands. Geoarchaeology Workshop

    DTIC Science & Technology

    2008-10-01

    unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 on the cover A petroglyph (rock art) in the Agua Fria National Monument...Fluorescence Petroglyphs can be found throughout the 71,000 acres that make up the Agua Fria National Monument. Photo credit: Bureau of Land Management...Andy DoD-Navy NAVFAC SW – SCIR Young, Craig Contractor Far Western Anthropological Research Group Big Rocks in the Agua Fria National Monument

  12. Quaternary Slip History for the Agua Blanca Fault, northern Baja California, Mexico

    NASA Astrophysics Data System (ADS)

    Gold, P. O.; Behr, W. M.; Rockwell, T. K.; Fletcher, J. M.

    2017-12-01

    The Agua Blanca Fault (ABF) is the primary structure accommodating San Andreas-related right-lateral slip across the Peninsular Ranges of northern Baja California. Activity on this fault influences offshore faults that parallel the Pacific coast from Ensenada to Los Angeles and is a potential threat to communities in northern Mexico and southern California. We present a detailed Quaternary slip history for the ABF, including new quantitative constraints on geologic slip rates, slip-per-event, the timing of most recent earthquake, and the earthquake recurrence interval. Cosmogenic 10Be exposure dating of clasts from offset fluvial geomorphic surfaces at 2 sites located along the western, and most active, section of the ABF yield preliminary slip rate estimates of 2-4 mm/yr and 3 mm/yr since 20 ka and 2 ka, respectively. Fault zone geomorphology preserved at the younger site provides evidence for right-lateral surface displacements measuring 2.5 m in the past two ruptures. Luminescence dating of an offset alluvial fan at a third site is in progress, but is expected to yield a slip rate relevant to the past 10 kyr. Adjacent to this third site, we excavated 2 paleoseismic trenches across a sag pond formed by a right step in the fault. Preliminary radiocarbon dates indicate that the 4 surface ruptures identified in the trenches occurred in the past 6 kyr, although additional dating should clarify earthquake timing and the mid-Holocene to present earthquake recurrence interval, as well as the likely date of the most recent earthquake. Our new slip rate estimates are somewhat lower than, but comparable within error to, previous geologic estimates based on soil morphology and geodetic estimates from GPS, but the new record of surface ruptures exposed in the trenches is the most complete and comprehensively dated earthquake history yet determined for this fault. Together with new and existing mapping of tectonically generated geomorphology along the ABF, our constraints

  13. New geologic slip rates for the Agua Blanca Fault, northern Baja California, Mexico

    NASA Astrophysics Data System (ADS)

    Gold, P. O.; Behr, W. M.; Fletcher, J. M.; Hinojosa-Corona, A.; Rockwell, T. K.

    2015-12-01

    Within the southern San Andreas transform plate boundary system, relatively little is known regarding active faulting in northern Baja California, Mexico, or offshore along the Inner Continental Borderland. The inner offshore system appears to be fed from the south by the Agua Blanca Fault (ABF), which strikes northwest across the Peninsular Ranges of northern Baja California. Therefore, the geologic slip rate for the ABF also provides a minimum slip rate estimate for the offshore system, which is connected to the north to faults in the Los Angeles region. Previous studies along the ABF determined slip rates of ~4-6 mm/yr (~10% of relative plate motion). However, these rates relied on imprecise age estimates and offset geomorphic features of a type that require these rates to be interpreted as minima, allowing for the possibility that the slip rate for the ABF may be greater. Although seismically quiescent, the surface trace of the ABF clearly reflects Holocene activity, and given its connectivity with the offshore fault system, more quantitative slip rates for the ABF are needed to better understand earthquake hazard for both US and Mexican coastal populations. Using newly acquired airborne LiDAR, we have mapped primary and secondary fault strands along the segmented western 70 km of the ABF. Minimal development has left the geomorphic record of surface slip remarkably well preserved, and we have identified abundant evidence meter to km scale right-lateral displacement, including new Late Quaternary slip rate sites. We verified potential reconstructions at each site during summer 2015 fieldwork, and selected an initial group of three high potential slip rate sites for detailed mapping and geochronologic analyses. Offset landforms, including fluvial terrace risers, alluvial fans, and incised channel fill deposits, record displacements of ~5-80 m, and based on minimal soil development, none appear older than early Holocene. To quantitatively constrain landform ages

  14. Prevalence and correlates of 'agua celeste' use among female sex workers who inject drugs in Ciudad Juarez, Mexico.

    PubMed

    Morris, Meghan D; Case, Patricia; Robertson, Angela M; Lozada, Remedios; Vera, Alicia; Clapp, John D; Medina-Mora, Maria Elena; Strathdee, Steffanie A

    2011-09-01

    Agua celeste, or "heavenly water", is the street name for a sky-blue colored solvent reportedly inhaled or ingested to produce an intoxicating effect. Study aims were to (1) describe prevalence of agua celestse (AC) use, and (2) identify correlates of lifetime and recent use of AC use among female sex workers who also inject drugs (FSW-IDUs) in northern Mexico. Between 2008 and 2010, baseline data from FSW-IDUs≥18 years old living in Tijuana or Ciudad Juarez participating in a longitudinal behavioral intervention were analyzed using logistic regression. Among 623 FSW-IDUs (307 from Tijuana and 316 from Ciudad Juarez (CJ)), 166 (26%) reported ever using AC, all of whom lived in CJ. Among the CJ sample, lifetime prevalence of AC use was 53%, median age of first use was 16 years (IQR: 14-23), and 10% reported it as their first abused substance. Ever using AC was independently associated with ever being physically abused and younger age, and was marginally associated with initiating injection drug use and regular sex work at age eighteen or younger. Among those ever using AC, 70/166 (42.2%) reported using it within the last 6 months, which was independently associated with using drugs with clients before or during sex, being on the street more than 8h per day, and younger age. We observed considerable geographic variation in the use of AC in northern Mexico. Future studies exploring factors influencing use, its precise formulation(s), and its potential health effects are needed to guide prevention and treatment. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  15. Prevalence and Correlates of ‘Agua Celeste’ Use among Female Sex Workers who Inject Drugs in Ciudad Juarez, Mexico

    PubMed Central

    Morris, Meghan D.; Case, Patricia; Robertson, Angela M.; Lozada, Remedios; Vera, Alicia; Clapp, John D.; Medina-Mora, Maria Elena; Strathdee, Steffanie A.

    2011-01-01

    Background Agua celeste, or “heavenly water,” is the street name for a sky-blue colored solvent reportedly inhaled or ingested to produce an intoxicating effect. Study aims were to (1) describe prevalence of Agua Celestse (AC) use, and (2) identify correlates of lifetime and recent use of AC use among female sex workers who also inject drugs (FSW-IDUs) in northern Mexico. Methods Between 2008 and 2010, baseline data from FSW-IDUs ≥ 18 years old living in Tijuana or Ciudad Juarez participating in a longitudinal behavioral intervention were analyzed using logistic regression. Results Among 623 FSW-IDUs (307 from Tijuana and 316 from Ciudad Juarez (CJ)), 166 (26%) reported ever using AC, all of whom lived in CJ. Among the CJ sample, lifetime prevalence of AC use was 53%, median age of first use was 16 years (IQR: 14–23), and 10% reported it as their first abused substance. Ever using AC was independently associated with ever being physically abused and younger age, and was marginally associated with initiating injection drug use and regular sex work at age eighteen or younger. Among those ever using AC, 70/166 (42.2%) reported using it within the last 6 months, which was independently associated with using drugs with clients before or during sex, being on the street more than 8 hours per day, and younger age. Discussion We observed considerable geographic variation in the use of AC in northern Mexico. Future studies exploring factors influencing use, its precise formulation(s), and its potential health effects are needed to guide prevention and treatment. PMID:21441001

  16. Geology and geochemistry of Pelagatos, Cerro del Agua, and Dos Cerros monogenetic volcanoes in the Sierra Chichinautzin Volcanic Field, south of México City

    NASA Astrophysics Data System (ADS)

    Agustín-Flores, Javier; Siebe, Claus; Guilbaud, Marie-Noëlle

    2011-04-01

    This study focuses on the geology and geochemistry of three closely-spaced monogenetic volcanoes that are located in the NE sector of the Sierra Chichinautzin Volcanic Field near México City. Pelagatos (3020 m.a.s.l.) is a small scoria cone (0.0017 km 3) with lava flows (0.036 km 3) that covered an area of 4.9 km 2. Cerro del Agua scoria cone (3480 m.a.s.l., 0.028 km 3) produced several lava flows (0.24 km 3) covering an area of 17.6 km 2. Dos Cerros is a lava shield which covers an area of 80.3 km 2 and is crowned by two scoria cones: Tezpomayo (3080 m.a.s.l., 0.022 km 3) and La Ninfa (3000 m.a.s.l., 0.032 km 3). The eruptions of Cerro del Agua and Pelagatos occurred between 2500 and 14,000 yr BP. The Dos Cerros eruption took place close to 14,000 yr BP as constrained by radiocarbon dating. Rocks from these three volcanoes are olivine-hypersthene normative basaltic andesites and andesites with porphyritic, aphanitic, and glomeroporphyritic textures. Their mineral assemblages include olivine, clinopyroxene, and orthopyroxene phenocrysts (≤ 10 vol.%) embedded in a trachytic groundmass which consists mainly of plagioclase microlites and glass. Pelagatos rocks also present quartz xenocrysts. Due to their high Cr and Ni contents, and high Mg#s, Pelagatos rocks are considered to be derived from primitive magmas, hence the importance of this volcano for understanding petrogenetic processes in this region. Major and trace element abundances and petrography of products from these volcanoes indicate a certain degree of crystal fractionation during ascent to the surface. However, the magmas that formed the volcanoes evolved independently from each other and are not cogenetically related. REE, HFSE, LILE, and isotopic (Sr, Nd, and Pb) compositions point towards a heterogeneous mantle source that has been metasomatized by aqueous/melt phases from the subducted Cocos slab. There is no clear evidence of important crustal contributions in the compositions of Pelagatos and

  17. Mineralogy, structural control and age of the Incachule Sb epithermal veins, the Cerro Aguas Calientes collapse caldera, Central Puna

    NASA Astrophysics Data System (ADS)

    Salado Paz, Natalia; Petrinovic, Iván; Do Campo, Margarita; Brod, José Affonso; Nieto, Fernando; da Silva Souza, Valmir; Wemmer, Klauss; Payrola, Patricio; Ventura, Roberto

    2018-03-01

    The Incachule Sb epithermal veins is located near to the N-E rim of the Cerro Aguas Calientes collapse caldera (17.5-10.8 Ma), in the geologic province of Puna, Salta- Argentina. It is hosted in Miocene felsic volcanic rocks with continental arc signature. The district includes twelve vein systems with mineralization of Sb occurring in hydrothermal breccias and stockwork. The veins are composed of quartz-sulfide with pyrite, stibnite and arsenopyrite. All around the veins, wall rocks are variably altered to clay minerals and sulfates in an area of around 2.5 km wide by more than 7 km long. The hydrothermal alterations recognized are: silicic, phyllic and argillic. The veins are characterized by high contents of Sb, As, and Tl and intermediate contents of Pb-Zn-Cu, and traces of Ag and Au. Homogenization and ice-melting temperatures of fluid inclusions vary from 125 °C to 189 °C and -2.4 °C to -0.8 °C. The isotopic data indicated a range of δ34S -3.04‰ to +0.72‰ consistent with a magmatic source for sulfur. We present the firsts K-Ar ages for hydrothermal illite/smectite mixed layers (I/SR1, 60% illite layers) and illite that constrain the age of the ore deposit (8.5-6.7 ± 0.2 Ma). The data shown here, let characterized the Incachule district as a shallow low sulfidation epithermal system hosted in a collapse caldera. Our data also indicate that mineralization is structurally controlled by a fault system related to the 10.3 Ma collapse of Aguas Calientes caldera. The interpreted local stress field is consistent with the regional one.

  18. Relaciones hidrogeologicas y medioambientales entre el mar mediterraneo, El saladar y el acuifero de agua amarga (provincia de alicante). Incidencia de las explotaciones de las desaladoras de alicante I Y II Y medidas correctoras

    NASA Astrophysics Data System (ADS)

    Manteca, Ivan Alhama

    The Agua Amarga coastal aquifer, located in the south of Alicante province, has been subjected to successive anthropogenic actions: salt works activity (1925-1975) and water withdrawal to supply the Alicante I and II desalination plants (since 2003). These interventions have influenced the salinity and the flow regime. Due to the existence of a salt marsh of ecological interest linked to the aquifer, the 'Mancomunidad de los Canales del Taibilla' (agency responsible for the desalination plants) designed a piezometric network for monitoring piezometry and electrical conductivity (in operation since May 2008). Soil humidity and piezometrics levels have been recovered by means of a seawater pouring programme over the salt marsh (since December 2009),which represents the third anthropic intervention. In this memoria, we investigate the Agua Amarga coastal aquifer to develop a physical conceptual model. Firstly, the study area is characterized in relation to climatology, geology, geomorphology and hydrogeology, using published information, describing, in addition, the desalination plants catchment system. Next, based on hydrogeological studies prior to the start up of the desalination plants, the aquifer is characterized: type, lithology, hydraulic parameters, thickness, surface extension, etc. Water quantity relating to rainfall, water withdrawal and pourings over the salt marsh, have been integrated in conjunction with data from monthly piezometric campaigns. In adittion, in order to gain insight into the groundwater mixing processes, chemical and isotope analyses were carried out on meteoric water and groundwater samples taken at different locations. The results were used to elaborate a conceptual physical model and a water budget. As an extension tool to understand processes and assess aquifer management, a 3-D fluid-flow and solute-transport model is designed with SEAWAT. Also, the 2-D physical characterization of scenarios with seawater intrusion and salt flats is

  19. Agua Caliente Wind/Solar Project at Whitewater Ranch

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hooks, Todd; Stewart, Royce

    2014-12-16

    Agua Caliente Band of Cahuilla Indians (ACBCI) was awarded a grant by the Department of Energy (DOE) to study the feasibility of a wind and/or solar renewable energy project at the Whitewater Ranch (WWR) property of ACBCI. Red Mountain Energy Partners (RMEP) was engaged to conduct the study. The ACBCI tribal lands in the Coachella Valley have very rich renewable energy resources. The tribe has undertaken several studies to more fully understand the options available to them if they were to move forward with one or more renewable energy projects. With respect to the resources, the WWR property clearly hasmore » excellent wind and solar resources. The DOE National Renewable Energy Laboratory (NREL) has continued to upgrade and refine their library of resource maps. The newer, more precise maps quantify the resources as among the best in the world. The wind and solar technology available for deployment is also being improved. Both are reducing their costs to the point of being at or below the costs of fossil fuels. Technologies for energy storage and microgrids are also improving quickly and present additional ways to increase the wind and/or solar energy retained for later use with the network management flexibility to provide power to the appropriate locations when needed. As a result, renewable resources continue to gain more market share. The transitioning to renewables as the major resources for power will take some time as the conversion is complex and can have negative impacts if not managed well. While the economics for wind and solar systems continue to improve, the robustness of the WWR site was validated by the repeated queries of developers to place wind and/or solar there. The robust resources and improving technologies portends toward WWR land as a renewable energy site. The business case, however, is not so clear, especially when the potential investment portfolio for ACBCI has several very beneficial and profitable alternatives.« less

  20. Hydrometric, Hydrochemical, and Hydrogeophysical Runoff Characterization Across Multiple Land Covers in the Agua Salud Project, Panama

    NASA Astrophysics Data System (ADS)

    Litt, Guy Finley

    As the Panama Canal Authority faces sensitivity to water shortages, managing water resources becomes crucial for the global shipping industry's security. These studies address knowledge gaps in tropical water resources to aid hydrological model development and validation. Field-based hydrological investigations in the Agua Salud Project within the Panama Canal Watershed employed multiple tools across a variety of land covers to investigate hydrological processes. Geochemical tracers informed where storm runoff in a stream comes from and identified electrical conductivity (EC) as an economical, high sample frequency tracer during small storms. EC-based hydrograph separation coupled with hydrograph recession rate analyses identified shallow and deep groundwater storage-discharge relationships that varied by season and land cover. A series of plot-scale electrical resistivity imaging geophysical experiments coupled with rainfall simulation characterized subsurface flow pathway behavior and quantified respectively increasing infiltration rates across pasture, 10 year old secondary succession forest, teak (tectona grandis), and 30 year old secondary succession forest land covers. Additional soil water, groundwater, and geochemical studies informed conceptual model development in subsurface flow pathways and groundwater, and identified future research needs.

  1. Preliminary Image Map of the 2007 Buckweed Fire Perimeter, Agua Dulce Quadrangle, Los Angeles County, California

    USGS Publications Warehouse

    Clark, Perry S.; Scratch, Wendy S.; Bias, Gaylord W.; Stander, Gregory B.; Sexton, Jenne L.; Krawczak, Bridgette J.

    2008-01-01

    In the fall of 2007, wildfires burned out of control in southern California. The extent of these fires encompassed large geographic areas that included a variety of landscapes from urban to wilderness. The U.S. Geological Survey National Geospatial Technical Operations Center (NGTOC) is currently (2008) developing a quadrangle-based 1:24,000-scale image map product. One of the concepts behind the image map product is to provide an updated map in electronic format to assist with emergency response. This image map is one of 55 preliminary image map quadrangles covering the areas burned by the southern California wildfires. Each map is a layered, geo-registered Portable Document Format (.pdf) file. For more information about the layered geo-registered .pdf, see the readme file (http://pubs.usgs.gov/of/2008/1029/downloads/CA_Agua_Dulce_of2008-1029_README.txt). To view the areas affected and the quadrangles mapped in this preliminary project, see the map index (http://pubs.usgs.gov/of/2008/1029/downloads/CA_of2008_1029-1083_index.pdf) provided with this report.

  2. Spatiotemporal analysis of air conditions as a tool for the environmental management of a show cave (Cueva del Agua, Spain)

    NASA Astrophysics Data System (ADS)

    Fernandez-Cortes, A.; Calaforra, J. M.; Sanchez-Martos, F.

    We recorded the air temperature and carbon dioxide concentration within the Cueva del Agua, a cave in Spain, under natural conditions prior to the cave being opened to tourists. Geostatistical tools are useful techniques for characterizing microclimate parameters with the aim of adopting measures to ensure the conservation and sound environmental management of tourist caves. We modelled the spatial distribution of these microclimatic parameters over an annual cycle using iterative residual kriging, revealing the stratification of air related to the cave's topography. Replenishment of the cave air is activated by convective circulation that accompanies the development of inversions in the thermal gradient of the air. Comparison of the spatial distribution of each microclimatic parameter over time enables us to characterize the exchange of air between the cave interior and the outside, as well as identify potential areas that could be opened to tourists and determine suitable visiting schedules.

  3. Petrographic Evidence of Microbial Mats in the Upper Cretaceous Fish-Bearing, Organic-Rich Limestone, Agua Nueva Formation, Central Mexico

    NASA Astrophysics Data System (ADS)

    Blanco, A.; Maurrasse, F. J.; Hernández-Ávila, J.; Ángeles-Trigueros, S. A.; García-Cabrera, M. E.

    2013-05-01

    We document petrographic evidence of microbial mats in the Upper Cretaceous Agua Nueva Formation in the area of Xilitla (San Luis Potosí, Central Mexico), located in the southern part of the Tampico-Misantla basin. The sequence consists predominantly of alternating decimeter-thick beds of fossiliferous dark laminated limestone (C-org > 1.0wt%), and light gray, bioturbated limestone (C-org < 1.0wt%), with occasional brown shale and green bentonite layers. Well-preserved fossil-fish assemblages occur in the laminated dark limestone beds, which include shark teeth (cf. Ptychodus), scales of teleosteans (Ichthyodectiformes), as well as skeletal remains of holosteans (Nursallia. sp), and teleosteans (cf. Rhynchodercetis, Tselfatia, and unidentified Enchodontids). Thin section and SEM analyses of the laminated, dark limestones, reveal a micritic matrix consisting of dark and light sub-parallel wavy laminae, continuous and discontinuous folded laminae with shreds of organic matter, filaments, oncoids, and interlocking structures. The structures are identical to those previously described for the Cenomanian-Turonian Indidura Fm at Parras de la Fuente (Coahuila state) demonstrated to be of microbial origin (Duque-Botero and Maurrasse, 2005; 2008). These structures are also analogous to microbial mats in present environments, and Devonian deposits (Kremer, 2006). In addition, the laminae at Xilitla include filamentous bacterial structures, as thin and segmented red elements. In some thin sections, filaments appear to be embedded within the crinkly laminae and shreds showing the same pattern of folding, suggestive of biomorphic elements that represent the main producers of the organic matter associated with the laminae. Thus, exceptional bacterial activity characterizes sedimentation during the accumulation of the Agua Nueva Formation. Oxygen-deficient conditions related to the microbial mats were an important element in the mass mortality and preservation of the fish

  4. Characterisation of the sedimentary processes responsible for the filling and excavation of two intra mountainous basins (Agua Amarga and Collon Cura) in the Andes of Neuquén (Argentina) during the Neogene

    NASA Astrophysics Data System (ADS)

    Bonnel, C.; Huyghe, D.; Nivière, B.; Messager, G.; Dhont, D.; Fasentieux, B.; Hervouët, Y.; Xavier, J.-P.

    2012-04-01

    Intramontane basins constitute potential good recorders of orogenic systems deformation history through the documentation of their remnant sedimentary filling and observation of syntectonic growth strata. In this work, we focus on the Neuquén basin, located on the eastern flank of the Andes between 32°S and 41°S latitude. It has been structured since the late Triassic, first as back arc basin and as compressive foreland basin since the upper Cretaceous. Most of the sedimentary filling is composed of Mesozoic sediments, which have been importantly studied because of their hydrocarbon potential. On the contrary, Cenozoic tectonic and sedimentologic evolutions remain poorly documented in regard to the Mesozoic. The structural inheritance is very important and strongly influences the deformation and shortening rates from the North to the South of the basin. Thus, the northern part exhibits a classical configuration from the western high Andes, to younger fold and thrust belts and piggy-back basins to the East. On the contrary, no fold and thrust belt exist in the southern part of the basin and the deformation is restricted to the internal domain. Nevertheless, contemporaneous intramontane basins (the Agua Amarga to the North and the Collon Cura basin to the South) existed in these two parts of the basin and seem to have followed a similar evolution despite of a different structural context. To the North, the partial closing of the Agua Amarga basin by the growth of the Chuihuidos anticlines during the Miocene is characterised by the deposition of a fining upward continental sequence of ~250 m thick, from lacustrine environment at the base to alluvial and fluviatile environments in the upper part of the section. In the Collon Cura, the sedimentary filling, due to the rising of the Piedra del Aguila basement massif, reach at maximum 500 m and consist in fluvial tuffaceous material in the lower part to paleosoils and coarse conglomeratic fluvial deposits in the upper

  5. Introduccion a la hidraulica de aguas subterraneas : un texto programado para auto-ensenanza

    USGS Publications Warehouse

    Bennett, Gordon D.

    1987-01-01

    Este ' texto programado esta diseflado para ayudarle a comprender la teoria de la hidniulica de aguas subterraneas por medio de la auto-enseflanza. La instrucci6n programada es un enfoque a una materia, un metodo de aprender;que no elimina el esfuerzo mental del proceso de aprendizaje. Algunas secciones de este programa necesitan solamente ser leidas; otras tendrian que ser elaboradas con lapiz y papel. Algunas preguntas pueden ser contestadas directamente; otras requieren calculos. A medida que se avanza en el texto, tendra que consultar frecuentemente textos o referencias sobre matematicas, mecanica de fluidos e hidrologia. En cada una de las ocho partes del texto, inicie el programa de instrucci6n leyendo la Secci6n 1. Elija una respuesta a la pregunta al final de la secci6n y dirijase a la nueva secci6n indicada al lado de la respuesta escogida. Si su respuesta fue correcta, pase a la secci6n que contiene materia nueva y otra pregunta, y proceda tal como en la Secci6n 1. Si su respuesta no fue correcta, dirijase a la secci6n que contiene explicaciones adicionales sobre el tema anterior y que le indica volver a la pregunta inicial e intentar de nuevo. En este caso, valdra Ia pena repasar el material de la secci6n anterior. Continue de esta man era en el programa hasta que llegue a Ia secci6n que indica el final de la parte. Observe que aunque las secciones estan en orden numerico en cada una de las ocho partes, por lo general, usted no procedeni en secuencia numerica (Secci6n 1 ala Secci6n 2, etc.) de principia a fin.

  6. Aquifers and hyporheic zones: Towards an ecological understanding of groundwater

    NASA Astrophysics Data System (ADS)

    Hancock, Peter J.; Boulton, Andrew J.; Humphreys, William F.

    2005-03-01

    Ecological constraints in subsurface environments relate directly to groundwater flow, hydraulic conductivity, interstitial biogeochemistry, pore size, and hydrological linkages to adjacent aquifers and surface ecosystems. Groundwater ecology has evolved from a science describing the unique subterranean biota to its current form emphasising multidisciplinary studies that integrate hydrogeology and ecology. This multidisciplinary approach seeks to elucidate the function of groundwater ecosystems and their roles in maintaining subterranean and surface water quality. In aquifer-surface water ecotones, geochemical gradients and microbial biofilms mediate transformations of water chemistry. Subsurface fauna (stygofauna) graze biofilms, alter interstitial pore size through their movement, and physically transport material through the groundwater environment. Further, changes in their populations provide signals of declining water quality. Better integrating groundwater ecology, biogeochemistry, and hydrogeology will significantly advance our understanding of subterranean ecosystems, especially in terms of bioremediation of contaminated groundwaters, maintenance or improvement of surface water quality in groundwater-dependent ecosystems, and improved protection of groundwater habitats during the extraction of natural resources. Overall, this will lead to a better understanding of the implications of groundwater hydrology and aquifer geology to distributions of subsurface fauna and microbiota, ecological processes such as carbon cycling, and sustainable groundwater management. Les contraintes écologiques dans les environnements de subsurface sont en relation directe avec les écoulements des eaux souterraines, la conductivité hydraulique, la biogéochimie des milieux interstitiels, la taille des pores, et les liens hydrologiques avec les aquifères et les écosystèmes adjacents. L'écologie des eaux souterraines a évolué d'une science décrivant uniquement les

  7. Serologic survey of infectious diseases in populations of maned wolf (Chrysocyon brachyurus) and crab-eating fox (Cerdocyon thous) from Aguas Emendadas Ecological Station, Brazil.

    PubMed

    Proença, Laila M; Silva, Jean C R; Galera, Paula D; Lion, Marília B; Marinho-Filho, Jader S; Ragozo, Alessandra Mara Alves; Gennari, Solange Maria; Dubey, J P; Vasconcellos, Silvio Arruda; Souza, Gisele Oliveira; Pinheiro, José Wilton; Santana, Vânia Lúcia de Assis; França, Gilvan L; Rodrigues, Flávio H G

    2013-03-01

    Domestic dogs are reservoirs for many infectious diseases and may represent a potential source of infection for wild canid populations. A serologic investigation of antibodies to Toxoplasma gondii, Neospora caninum, Brucella abortus, and Leptospira spp. was conducted on three maned wolves (Chrysocyon brachyurus) and seven crab-eating foxes (Cerdocyon thous), all free-living, at the Aguas Emendadas Ecological Station (ESECAE), Federal District, Brazil, between February and October 2006. Out of the 10 samples analyzed, eight (80%) were seropositive for T. gondii: 3/3 (100%) of the maned wolves and 5/7 (71.4%) of the crab-eating foxes. None of the animals presented anti-N. caninum, B. abortus, and Leptospira spp. antibodies. This study demonstrated that the wild canid populations at ESECAE presented high exposure to T. gondii and indicated that there is high environmental contamination at the Station, which can be attributed to its proximity to urban zones, the presence of domestic cats in the study area, or the existence of other wild infected felines.

  8. Hydrogeology and sustainable future groundwater abstraction from the Agua Verde aquifer in the Atacama Desert, northern Chile

    NASA Astrophysics Data System (ADS)

    Urrutia, Javier; Jódar, Jorge; Medina, Agustín; Herrera, Christian; Chong, Guillermo; Urqueta, Harry; Luque, José A.

    2018-03-01

    The hyper-arid conditions prevailing in Agua Verde aquifer in northern Chile make this system the most important water source for nearby towns and mining industries. Due to the growing demand for water in this region, recharge is investigated along with the impact of intense pumping activity in this aquifer. A conceptual model of the hydrogeological system is developed and implemented into a two-dimensional groundwater-flow numerical model. To assess the impact of climate change and groundwater extraction, several scenarios are simulated considering variations in both aquifer recharge and withdrawals. The estimated average groundwater lateral recharge from Precordillera (pre-mountain range) is about 4,482 m3/day. The scenarios that consider an increase of water withdrawal show a non-sustainable groundwater consumption leading to an over-exploitation of the resource, because the outflows surpasses inflows, causing storage depletion. The greater the depletion, the larger the impact of recharge reduction caused by the considered future climate change. This result indicates that the combined effects of such factors may have a severe impact on groundwater availability as found in other groundwater-dependent regions located in arid environments. Furthermore, the scenarios that consider a reduction of the extraction flow rate show that it may be possible to partially alleviate the damage already caused to the aquifer by the continuous extractions since 1974, and it can partially counteract climate change impacts on future groundwater availability caused by a decrease in precipitation (and so in recharge), if the desalination plant in Taltal increases its capacity.

  9. Documentation and Testing of the WEAP Model for the Rio Grande/Bravo Basin

    DTIC Science & Technology

    2006-08-01

    border between Texas and the Mexican states of Coahuila, Nuevo Leon and Tamaulipas (Appendix B, Figure 32). There are four reservoirs of interest in this...Camargo - Ciudad Acuna - Ciudad Anhuac - Ciudad Juarez - Matamoros - Metropolitan Monterrey - Nuevo Laredo - Reynosa - Piedras Negras...Rivera, and Jorge A. Hidalgo. (2001). “Sistema de apoyo a la toma de decisions para el manejo integral del agua en cuencas.” IMTA/CNA, Proyecto

  10. Sediment Budget Calculations Oceanside, California.

    DTIC Science & Technology

    1983-12-01

    Volume of Sediment Dredged from Agua Hedionda Lagoon vs. Time ............................. 13 7 Cumulative Volume of Accretion or Erosion as a Function...17 10 Oceanside Sub-Cell 2-3, Oceanside Harbor ............ 17 11 Oceanside Sub-Cell 3-4, Oceanside Harbor to Agua Hedionda Lagoon...18 12 Oceanside Sub-Cell 4-5, Agua Hedionda Lagoon ........ 18 13 Oceanside Sub-Cell 5-6, Agua Hedionda Lagoon to Southern

  11. Basic diagnosis of solid waste generated at Agua Blanca State Park to propose waste management strategies.

    PubMed

    Laines Canepa, José Ramón; Zequeira Larios, Carolina; Valadez Treviño, Maria Elena Macías; Garduza Sánchez, Diana Ivett

    2012-03-01

    State parks are highly sensitive areas of great natural importance and tourism value. Herein a case study involving a basic survey of solid waste which was carried out in 2006 in Agua Blanca State Park, Macuspana, Tabasco, Mexico with two sampling periods representing the high and low tourist season is presented. The survey had five objectives: to find out the number of visitors in the different seasons, to consider the daily generation of solid waste from tourist activities, to determine bulk density, to select and quantify sub-products; and to suggest a possible treatment. A daily average of 368 people visited the park: 18,862 people in 14 days during the high season holiday (in just one day, Easter Sunday, up to 4425 visitors) and 2092 visitors in 43 days during the low season. The average weight of the generated solid waste was 61.267 kg day(-1) and the generated solid waste average per person was 0.155 kg person(-1 ) day(-1). During the high season, the average increased to 0.188 kg person(-1 ) day(-1) and during the low season, the average decreased to 0.144 kg person(-1 ) day(-1). The bulk density average was 75.014 kg m(-3), the maximum value was 92.472 kg m(-3) and the minimum was 68.274 kg m(-3). The sub-products comprised 54.52% inorganic matter; 32.03% organic matter, 10.60% non-recyclable and 2.85% others. Based on these results, waste management strategies such as reuse/recycling, aerobic and anaerobic digestion, the construction of a manual landfill and the employment of a specialist firm were suggested.

  12. Infórmese sobre el programa de WIFIA

    EPA Pesticide Factsheets

    La Ley de finanzas e innovación de la infraestructura del agua de 2014 estableció el programa de WIFIA, un programa federal crediticio administrado por la EPA para proyectos elegibles de infraestructura de agua y aguas sanitarias.

  13. Quantifying Hydrological Ecosystem Services of Various Land Covers and Uses on Small Experimental Catchments within the Panama Canal Watershed: The Agua Salud Project

    NASA Astrophysics Data System (ADS)

    Crouch, T. D.; Ogden, F. L.; Agua Salud Project

    2011-12-01

    As a part of the Agua Salud Project, a baseline characterization of hydrologic processes on the small catchment scale (~0.24 to 2.0 km2) is assessed across different land uses and covers typical to rural Panama. The land covers being monitored include a mature secondary forest, a disturbed catchment with a mosaic of various aged secondary growth and agricultural use, an active pasture and a monoculture invasive grass site as experimental controls, and two treated catchments that were recently abandoned pastures converted to teak and native species timber plantations. The catchments are found within Panama's protected Soberania National Park and the adjacent headwaters of the Agua Salud and Mendoza Rivers, all part of the greater Panama Canal Watershed. Using hydrological data from the first two and a half years of the project, three main ecosystem services are observed. The forested area exhibited lower storm event peaks, decreased flashiness, and greater stream flow during the dry season compared to the disturbed mosaic site. Lower hydrograph peaks and flashiness mitigate the risk of substantial flood damage during the major flood events generally seen in Panama between October and December. The mature forest (1.35 km2) catchment has shown lower average flood peaks in comparison to the disturbed site. For storm peaks less than 6 mm/hr, flood peaks are on average 51% lower. For storm peaks greater than 6 mm/hr, flood peaks are approximately 40% lower. In 1998, draft restrictions were imposed in the Panama Canal because of a deficit of dry season water after an El Niño-Southern Oscillation resulted in decreased wet season rainfall. The water that is available during the end of the dry season has the potential to insure the full operation of the Canal during El Niño drought years. Toward the end of the dry season (March through May) our data shows that roughly 34% more water was available during a relatively dry year with respect to antecedent wet season rainfall

  14. Integrating geophysical and hydrochemical borehole-log measurements to characterize the Chalk aquifer, Berkshire, United Kingdom

    NASA Astrophysics Data System (ADS)

    Schürch, Marc; Buckley, David

    2002-09-01

    Geophysical and hydrochemical borehole-logging techniques were integrated to characterize hydraulic and hydrogeochemical properties of the Chalk aquifer at boreholes in Berkshire, UK. The down-hole measurements were made to locate fissures in the chalk, their spatial extent between boreholes, and to determine the groundwater chemical quality of the water-bearing layers. The geophysical borehole logging methods used were caliper, focused resistivity, induction resistivity, gamma ray, fluid temperature, fluid electrical conductivity, impeller and heat-pulse flowmeter, together with borehole wall optical-imaging. A multiparameter data transmitter was used to measure groundwater temperature, electrical conductivity, dissolved oxygen, pH, and redox potential of the borehole fluid down-hole. High permeability developed at the Chalk Rock by groundwater circulation provides the major flow horizon at the Banterwick Barn study site and represents a conduit system that serves as an effective local hydraulic connection between the boreholes. The Chalk Rock includes several lithified solution-ridden layers, hardgrounds, which imply a gap in sedimentation possibly representing an unconformity. Lower groundwater temperature, high dissolved-oxygen content, and flowmeter evidence of preferential groundwater flow in the Chalk Rock indicated rapid groundwater circulation along this horizon. By repeating the logging at different times of the year under changing hydraulic conditions, other water-inflow horizons within the Chalk aquifer were recognized. Résumé. Des techniques géophysiques et hydrochimiques de diagraphies en forage ont été mises en oeuvre pour caractériser les propriétés hydrauliques et hydrogéochimiques de l'aquifère de la craie dans des forages du Berkshire (Grande-Bretagne). Les mesures en descente ont été faites pour localiser les fissures dans la craie et leur développement spatial entre forages, et pour déterminer la qualité de l'eau souterraine des

  15. Testing Pixel Translation Digital Elevation Models to Reconstruct Slip Histories: An Example from the Agua Blanca Fault, Baja California, Mexico

    NASA Astrophysics Data System (ADS)

    Wilson, J.; Wetmore, P. H.; Malservisi, R.; Ferwerda, B. P.; Teran, O.

    2012-12-01

    We use recently collected slip vector and total offset data from the Agua Blanca fault (ABF) to constrain a pixel translation digital elevation model (DEM) to reconstruct the slip history of this fault. This model was constructed using a Perl script that reads a DEM file (Easting, Northing, Elevation) and a configuration file with coordinates that define the boundary of each fault segment. A pixel translation vector is defined as a magnitude of lateral offset in an azimuthal direction. The program translates pixels north of the fault and prints their pre-faulting position to a new DEM file that can be gridded and displayed. This analysis, where multiple DEMs are created with different translation vectors, allows us to identify areas of transtension or transpression while seeing the topographic expression in these areas. The benefit of this technique, in contrast to a simple block model, is that the DEM gives us a valuable graphic which can be used to pose new research questions. We have found that many topographic features correlate across the fault, i.e. valleys and ridges, which likely have implications for the age of the ABF, long term landscape evolution rates, and potentially provide conformation for total slip assessments The ABF of northern Baja California, Mexico is an active, dextral strike slip fault that transfers Pacific-North American plate boundary strain out of the Gulf of California and around the "Big Bend" of the San Andreas Fault. Total displacement on the ABF in the central and eastern parts of the fault is 10 +/- 2 km based on offset Early-Cretaceous features such as terrane boundaries and intrusive bodies (plutons and dike swarms). Where the fault bifurcates to the west, the northern strand (northern Agua Blanca fault or NABF) is constrained to 7 +/- 1 km. We have not yet identified piercing points on the southern strand, the Santo Tomas fault (STF), but displacement is inferred to be ~4 km assuming that the sum of slip on the NABF and STF is

  16. Cyanobacteria/Foraminifera Association from Anoxic/Dysoxic Beds of the Agua Nueva Formation (Upper Cretaceous - Cenomanian/Turonian) at Xilitla, San Luis Potosi, Central Mexico

    NASA Astrophysics Data System (ADS)

    Blanco-Piñón, A.; Maurrasse, F. J.; Rojas-León, A.; Duque-Botero, F.

    2008-05-01

    The Agua Nueva Formation in the vicinity of Xilitla, State of San Luis Potosí, Central Mexico, consists of interbedded brown shale (Grayish orange 10YR 7/4 to Moderate yellowish brown 10YR 5/4) and dark-gray fossiliferous limestone (Bluish gray 5B 6/1 to Dark bluish gray 5B 4/1), varying between 10 and 20 cm in thickness. The sequence also includes 2 to 4 cm- thick intermittent bentonite layers (Moderate greenish yellow 10Y 7/4, to dark greenish yellow 10Y 6/6 and Light olive 10Y 5/4). At the field scale, shaly intervals show no apparent internal structures, whereas most limestone beds show primary lamination at the millimeter scale (1-2 mm), and intermittent layers of black chert of about 5 cm thick. Pyrite is present as disseminated crystals and as 2 cm-thick layers. Bioturbation or macrobenthic organisms other than inoceramids do not occur in the Agua Nueva Formation at Xilitla. Unusual macrofossils are present only in limestone strata, and consist of well- preserved diverse genera of fishes such as sharks, Ptychodus sp. and teleosteans, Rhynchodercetis sp., Tselfatia sp., Goulmimichthys sp., and scales of Ichtyodectiformes, as well as ammonites and inoceramids (Blanco et al., 2006). The presence of Inoceramus (Mytyloides) labiatus (Maldonado-Koederll, 1956) indicates an Early Turonian age for the sequence. Total carbonate content (CaCO3 = TIC) varies between 62 and 94% in the Limestone beds, which yield Total Organic Carbon (TOC) from 0.4% to 2.5%; the shale intervals contain TIC values consistently lower than 33% and TOC lower than 0.8% Microscopically the limestone beds vary from mudstone to packstone composed essentially of coccoid cyanobacteria similar to coeval deposits in northeastern Mexico, Coahuila State, at Parras de La Fuente (Duque- Botero 2006). Similarly, the microspheroids are spherical to sub-spherical, and occur as isolated elements or aggregates forming series of chains of parallel-packed light lamina 1-2 mm thick. Filamentous cyanobacteria

  17. Management Approaches for Water Quality Enhancement at Whitney Point and East Sidney Lake, New York

    DTIC Science & Technology

    1990-08-01

    flos- aguae Anabaena sp. (colonial blue-greens) 8-16-88 Aphanizomenon flos- aguae Anabaena planctonica Coccoid sp. (colonial blue-greens...Goelosphaeriui sp. Microcystis aerug~inosa Comphosphaeria sp. 9-9-88 Aphanizomenon flos- aguae Oscillatoria sp. Melosira spp. Table 9 Dominant Phytoplankton Species...study (Kennedy et al. 1988). Sampling period was initiated in early April, 1988 and completed in early September, 1988. In situ variables, measured at

  18. A late Holocene paleoenvironmental reconstruction from Agua Caliente, southern Belize, linked to regional climate variability and cultural change at the Maya polity of Uxbenká

    NASA Astrophysics Data System (ADS)

    Walsh, Megan K.; Prufer, Keith M.; Culleton, Brendan J.; Kennett, Douglas J.

    2014-07-01

    We report high-resolution macroscopic charcoal, pollen and sedimentological data for Agua Caliente, a freshwater lagoon located in southern Belize, and infer a late Holocene record of human land-use/climate interactions for the nearby prehistoric Maya center of Uxbenká. Land-use activities spanning the initial clearance of forests for agriculture through the drought-linked Maya collapse and continuing into the historic recolonization of the region are all reflected in the record. Human land alteration in association with swidden agriculture is evident early in the record during the Middle Preclassic starting ca. 2600 cal yr BP. Fire slowly tapered off during the Late and Terminal Classic, consistent with the gradual political demise and depopulation of the Uxbenká polity sometime between ca. 1150 and 950 cal yr BP, during a period of multiple droughts evident in a nearby speleothem record. Fire activity was at its lowest during the Maya Postclassic ca. 950-430 cal yr BP, but rose consistent with increasing recolonization of the region between ca. 430 cal yr BP and present. These data suggest that this environmental record provides both a proxy for 2800 years of cultural change, including colonization, growth, decline, and reorganization of regional populations, and an independent confirmation of recent paleoclimate reconstructions from the same region.

  19. An assessment of Spain's Programa AGUA and its implications for sustainable water management in the province of Almería, southeast Spain.

    PubMed

    Downward, Stuart R; Taylor, Ros

    2007-01-01

    Spain's Programa AGUA was proposed in 2004 as a replacement for the Spanish National Hydrological Plan and represented a fundamental policy shift in national water management from large inter-basin water transfers to a commitment to desalination. Twenty-one desalination facilities are planned for six provinces on the Spanish Mediterranean coast to supplement their water needs. These include the province of Almería that for the last 30 years has endured a net water abstraction overdraft leading to serious reservoir depletion and groundwater imbalances. Rising water use is a result of increasing demand to support irrigated agriculture (e.g. greenhouse horticulture) and for domestic needs (e.g. rapid urban growth and tourism development), which has led observers to question Almería's long-term water sustainability. Desalinated water alone is unlikely to be sufficient to make up these water deficits and water-users will have to accept a move to full-price water recovery by 2010 under the European Union (EU) Water Framework Directive of which Spain is a signatory. Anticipated water efficiencies resulting from higher water tariffs, increasing water reuse and water infrastructure improvements (including inter-basin transfers), in conjunction with increasing use of desalinated water, are expected to address the province's current water overdraft. However, Almería will need to balance its planned initiatives against long-term estimates of projected agricultural and domestic development and the environmental consequences of adopting a desalination-supported water future.

  20. Non-integrability vs. integrability in pentagram maps

    NASA Astrophysics Data System (ADS)

    Khesin, Boris; Soloviev, Fedor

    2015-01-01

    We revisit recent results on integrable cases for higher-dimensional generalizations of the 2D pentagram map: short-diagonal, dented, deep-dented, and corrugated versions, and define a universal class of pentagram maps, which are proved to possess projective duality. We show that in many cases the pentagram map cannot be included into integrable flows as a time-one map, and discuss how the corresponding notion of discrete integrability can be extended to include jumps between invariant tori. We also present a numerical evidence that certain generalizations of the integrable 2D pentagram map are non-integrable and present a conjecture for a necessary condition of their discrete integrability.

  1. Context Evaluation of Historical Sites in the Prado Basin

    DTIC Science & Technology

    1990-01-29

    Agua Mansa Cemetery. The basin was described as "a very sensitive area archaeologically," and it was noted that the coterminous aboriginal and...volume, Hall reported that the Agua Mansa Cemetery is a California Historical Landmark and would be eligible for listing on the National Register...estab- lished, composad of two settlements called La Placita and Agua Mansa. This colony was a focal point for Spanish people arriving from the United

  2. Dredging and Sedimentation Control -- 1980, Proceedings of a Symposium Held in Alexandria, Virginia, 22-23 April 1980,

    DTIC Science & Technology

    1980-01-01

    Island Naval Shipyard. Another two experiments involved by-passing sand around the inlet of Agua Hedionda 1-2 Lagoon, California, using fluidized trenches...closed duct configurations is discussed in Bailard and Inman (1975). The Agua Hedionda Lagoon selected for these experiments is located 30 miles...erations on a flooding tide direct the influx, depositing a sand bar. The latest of several system designs for Agua Hedionda Lagoon consisted of a l-4m deep

  3. Energy Systems Integration Facility Videos | Energy Systems Integration

    Science.gov Websites

    Facility | NREL Energy Systems Integration Facility Videos Energy Systems Integration Facility Integration Facility NREL + SolarCity: Maximizing Solar Power on Electrical Grids Redefining What's Possible for Renewable Energy: Grid Integration Robot-Powered Reliability Testing at NREL's ESIF Microgrid

  4. 76 FR 73504 - Amendment of Class E Airspace; Alice, TX

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ..., area. Cancellation of all standard instrument approach procedures at Old Hoppe Place Airport, Agua... Old Hoppe Place Airport, Agua Dulce, TX, due to the cancellation of all standard instrument approach...

  5. Environmental Impact Analysis Process. Volume 1. Preliminary Draft Environmental Impact Statement Construction and Operation of Space Launch Complex 7, Vandenberg Air Force Base, California

    DTIC Science & Technology

    1989-04-06

    Cfiada Agua Viva is a south-flowing, perennial drainage located east of the project area and fed by two springs near Wild Horse Flats. Perennial yields...from this drainage are expected to be less than five gallons per minute (gpm), or 60 acre-feet per year. Caflada Agua Viva has a watershed area of... Agua Viva drainages are shown in Table 3.2.1 (Surface Water Quality, Point Arguello Area). Notably high values of total hardness, specific

  6. 77 FR 49367 - Final Flood Elevation Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-16

    ... County. Verde Creek confluence. Approximately 500 feet +2593 downstream of the Agua Caliente Wash... Pima County. Tanque Verde Road. Approximately 0.4 mile +2624 upstream of East Tanque Verde Road. Agua...

  7. The Integrated Hazard Analysis Integrator

    NASA Technical Reports Server (NTRS)

    Morris, A. Terry; Massie, Michael J.

    2009-01-01

    Hazard analysis addresses hazards that arise in the design, development, manufacturing, construction, facilities, transportation, operations and disposal activities associated with hardware, software, maintenance, operations and environments. An integrated hazard is an event or condition that is caused by or controlled by multiple systems, elements, or subsystems. Integrated hazard analysis (IHA) is especially daunting and ambitious for large, complex systems such as NASA s Constellation program which incorporates program, systems and element components that impact others (International Space Station, public, International Partners, etc.). An appropriate IHA should identify all hazards, causes, controls and verifications used to mitigate the risk of catastrophic loss of crew, vehicle and/or mission. Unfortunately, in the current age of increased technology dependence, there is the tendency to sometimes overlook the necessary and sufficient qualifications of the integrator, that is, the person/team that identifies the parts, analyzes the architectural structure, aligns the analysis with the program plan and then communicates/coordinates with large and small components, each contributing necessary hardware, software and/or information to prevent catastrophic loss. As viewed from both Challenger and Columbia accidents, lack of appropriate communication, management errors and lack of resources dedicated to safety were cited as major contributors to these fatalities. From the accident reports, it would appear that the organizational impact of managers, integrators and safety personnel contributes more significantly to mission success and mission failure than purely technological components. If this is so, then organizations who sincerely desire mission success must put as much effort in selecting managers and integrators as they do when designing the hardware, writing the software code and analyzing competitive proposals. This paper will discuss the necessary and

  8. Wilber's Integral Theory and Dossey's Theory of Integral Nursing: An Examination of Two Integral Approaches in Nursing Scholarship.

    PubMed

    Shea, Linda; Frisch, Noreen

    2016-09-01

    The purpose of this article is to examine Dossey's theory of integral nursing in relation to its major theoretical source, Wilber's integral theory. Although several nursing scholars have written about integral theory in relation to nursing scholarship and practice, Dossey's theory of integral nursing may be influencing how nurses take up integral theory in a significant way due to an extensive outreach in the holistic nursing community. Despite this wide circulation, the theory of integral nursing has yet to be reviewed in the nursing literature. This article (a) compares Dossey's theory of integral nursing with Wilber's integral theory and (b) contrasts Dossey's integral approach with another integral approach used by other scholars of integral theory. © The Author(s) 2015.

  9. Integrating Art.

    ERIC Educational Resources Information Center

    BCATA Journal for Art Teachers, 1991

    1991-01-01

    These articles focus on art as a component of interdisciplinary integration. (1) "Integrated Curriculum and the Visual Arts" (Anna Kindler) considers various aspects of integration and implications for art education. (2) "Integration: The New Literacy" (Tim Varro) illustrates how the use of technology can facilitate…

  10. 76 FR 82291 - Combined Notice of Filings #2

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ... 12/30/11. Docket Numbers: ER12-21-002. Applicants: Agua Caliente Solar, LLC. Description: Notice of Change in Status and Request for Expedited Action of Agua Caliente Solar, LLC. Filed Date: 12/20/11...

  11. “SLIMPLECTIC” INTEGRATORS: VARIATIONAL INTEGRATORS FOR GENERAL NONCONSERVATIVE SYSTEMS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tsang, David; Turner, Alec; Galley, Chad R.

    2015-08-10

    Symplectic integrators are widely used for long-term integration of conservative astrophysical problems due to their ability to preserve the constants of motion; however, they cannot in general be applied in the presence of nonconservative interactions. In this Letter, we develop the “slimplectic” integrator, a new type of numerical integrator that shares many of the benefits of traditional symplectic integrators yet is applicable to general nonconservative systems. We utilize a fixed-time-step variational integrator formalism applied to the principle of stationary nonconservative action developed in Galley et al. As a result, the generalized momenta and energy (Noether current) evolutions are well-tracked. Wemore » discuss several example systems, including damped harmonic oscillators, Poynting–Robertson drag, and gravitational radiation reaction, by utilizing our new publicly available code to demonstrate the slimplectic integrator algorithm. Slimplectic integrators are well-suited for integrations of systems where nonconservative effects play an important role in the long-term dynamical evolution. As such they are particularly appropriate for cosmological or celestial N-body dynamics problems where nonconservative interactions, e.g., gas interactions or dissipative tides, can play an important role.« less

  12. Integration mechanisms and hospital efficiency in integrated health care delivery systems.

    PubMed

    Wan, Thomas T H; Lin, Blossom Yen-Ju; Ma, Allen

    2002-04-01

    This study analyzes integration mechanisms that affect system performances measured by indicators of efficiency in integrated delivery systems (IDSs) in the United States. The research question is, do integration mechanisms improve IDSs' efficiency in hospital care? American Hospital Association's Annual Survey (1998) and Dorenfest's Survey on Information Systems in Integrated Healthcare Delivery Systems (1998) were used to conduct the study, using IDS as the unit of analysis. A covariance structure equation model of the effects of system integration mechanisms on IDS performance was formulated and validated by an empirical examination of IDSs. The study sample includes 973 hospital-based integrated health care delivery systems operating in the United States, carried in the list of Dorenfests Survey on Information Systems in Integrated Health care Delivery Systems. The measurement indicators of system integration mechanisms are categorized into six related domains: informatic integration, case management, hybrid physician-hospital integration, forward integration, backward integration, and high tech medical services. The multivariate analysis reveals that integration mechanisms in system operation are positively correlated and positively affect IDSs' efficiency. The six domains of integration mechanisms account for 58.9% of the total variance in hospital performance. The service differentiation strategy such as having more high tech medical services have much stronger influences on efficiency than other integration mechanisms do. The beneficial effects of integration mechanisms have been realized in IDS performance. High efficiency in hospital care can be achieved by employing proper integration strategies in operations.

  13. A Web-based Tool for Transparent, Collaborative Urban Water System Planning for Monterrey, Mexico

    NASA Astrophysics Data System (ADS)

    Rheinheimer, D. E.; Medellin-Azuara, J.; Garza Díaz, L. E.; Ramírez, A. I.

    2017-12-01

    Recent rapid advances in web technologies and cloud computing show great promise for facilitating collaboration and transparency in water planning efforts. Water resources planning is increasingly in the context of a rapidly urbanizing world, particularly in developing countries. In such countries with democratic traditions, the degree of transparency and collaboration in water planning can mean the difference between success and failure of water planning efforts. This is exemplified in the city of Monterrey, Mexico, where an effort to build a new long-distance aqueduct to increase water supply to the city dramatically failed due to lack of transparency and top-down planning. To help address, we used a new, web-based water system modeling platform, called OpenAgua, to develop a prototype decision support system for water planning in Monterrey. OpenAgua is designed to promote transparency and collaboration, as well as provide strong, cloud-based, water system modeling capabilities. We developed and assessed five water management options intended to increase water supply yield and/or reliability, a dominant water management concern in Latin America generally: 1) a new long-distance source (the previously-rejected project), 2) a new nearby reservoir, 3) expansion/re-operation of an existing major canal, 4) desalination, and 5) industrial water reuse. Using the integrated modeling and analytic capabilities of OpenAgua, and some customization, we assessed the performance of these options for water supply yield and reliability to help identify the most promising ones. In presenting this assessment, we demonstrate the viability of using online, cloud-based modeling systems for improving transparency and collaboration in decision making, reducing the gap between citizens, policy makers and water managers, and future directions.

  14. Información básica sobre los arrecifes de coral

    EPA Pesticide Factsheets

    Los corales están en todos los océanos del mundo, tanto en las aguas superficiales como en las profundas. Tienen una relación simbiótica con las algas, necesitan aguas transparentes, superficiales, que

  15. What Is Energy Systems Integration? | Energy Systems Integration Facility |

    Science.gov Websites

    NREL What Is Energy Systems Integration? What Is Energy Systems Integration? Energy systems integration (ESI) is an approach to solving big energy challenges that explores ways for energy systems to Research Community NREL is a founding member of the International Institute for Energy Systems Integration

  16. Integrative psychotherapy.

    PubMed

    Kozarić-Kovacić, Dragica

    2008-09-01

    The main purposes of the article are to present the history of integration in psychotherapy, the reasons of the development integrative approaches, and the approaches to integration in psychotherapy. Three approaches to integration in psychotherapy exist: theoretical integration, theoretical eclecticism, and common factors in different psychotherapeutic trends. In integrative psychotherapy, the basic epistemology, theory, and clinical practice are based on the phenomenology, field theory, holism, dialogue, and co-creation of dialogue in the therapeutic relationship. The main criticism is that integrative psychotherapy suffers from confusion and many unresolved controversies. It is difficult to theoretically and methodologically define the clinically applied model that is based on such a different epistemological and theoretical presumptions. Integrative psychotherapy is a synthesis of humanistic psychotherapy, object relations theory, and psychoanalytical self psychology. It focuses on the dynamics and potentials of human relationships, with a goal of changing the relations and understanding internal and external resistances. The process of integrative psychotherapy is primarily focused on the developmental-relational model and co-creation of psychotherapeutic relationship as a single interactive event, which is not unilateral, but rather a joint endeavor by both the therapist and the patient/client. The need for a relationship is an important human need and represents a process of attunement that occurs as a response to the need for a relationship, a unique interpersonal contact between two people. If this need is not met, it manifests with the different feelings and various defenses. To meet this need, we need to have another person with whom we can establish a sensitive, attuned relationship. Thus, the therapist becomes this person who tries to supplement what the person did not receive. Neuroscience can be a source of integration through different therapies. We

  17. International Conference on Marine Corrosion and Fouling (5th), held 19-23 May 1980, Barcelona (Spain).

    DTIC Science & Technology

    1980-12-31

    aguas de puertos i talianos." C.A. Viviani and L.H. Disalvo ( Chile ) :,"Biofouling in a north-central Chilean coastal bay." A.F.A. Ghobashy and A.K. Hassan...34Estudio del mechanismo de formaci6n de incrustationes en enfriadores por el uso de agua de mer." S.M. Coelho de Souza Medeiros Bastos and L.R...naval con cubierta de pinturas en agua de mar sintetica." T. Skoulikidis and P. Vassiliou (Greece): "Kinetic data on the leaching of 152?- antifouling

  18. Energy Systems Integration News | Energy Systems Integration Facility |

    Science.gov Websites

    NREL News Energy Systems Integration News A monthly recap of the latest happenings at the Energy Systems Integration Facility and developments in energy systems integration (ESI) research at NREL ; said Vahan Gevorgian, chief engineer with NREL's Power Systems Engineering Center. "Results of

  19. Evaluating Simultaneous Integrals

    ERIC Educational Resources Information Center

    Kwong, Harris

    2012-01-01

    Many integrals require two successive applications of integration by parts. During the process, another integral of similar type is often invoked. We propose a method which can integrate these two integrals simultaneously. All we need is to solve a linear system of equations.

  20. Energy Systems Integration News | Energy Systems Integration Facility |

    Science.gov Websites

    Renewable Generation Integration Study (ERGIS), looks ahead to the year 2026 and examines how the Eastern accurately modeling the entire system at five-minute intervals for an entire year has never even been Integrated Network Testbed for Energy Grid Research and Technology Experimentation (INTEGRATE) project, up to

  1. Integrally Closed Rings

    NASA Astrophysics Data System (ADS)

    Tuganbaev, A. A.

    1982-04-01

    This paper studies integrally closed rings. It is shown that a semiprime integrally closed Goldie ring is the direct product of a semisimple artinian ring and a finite number of integrally closed invariant domains that are classically integrally closed in their (division) rings of fractions. It is shown also that an integrally closed ring has a classical ring of fractions and is classically integrally closed in it.Next, integrally closed noetherian rings are considered. It is shown that an integrally closed noetherian ring all of whose nonzero prime ideals are maximal is either a quasi-Frobenius ring or a hereditary invariant domain.Finally, those noetherian rings all of whose factor rings are invariant are described, and the connection between integrally closed rings and distributive rings is examined.Bibliography: 13 titles.

  2. ¿Qué está haciendo la EPA para proteger a los arrecifes de coral?

    EPA Pesticide Factsheets

    La EPA protege a los arrecifes de coral mediante la implementación de programas de la Ley de Agua Limpia que protegen la calidad del agua en cuencas y zonas costeras de las áreas con arrecifes de coral.

  3. HETEROGENEOUS INTEGRATION TECHNOLOGY

    DTIC Science & Technology

    2017-08-24

    provide a structure for this review. The history and the current status of integration technologies in each category are examined and product examples are...NEED HETEROGENEOUS INTEGRATION?............................................. 6 5. IMPACT OF HETEROGENEOUS INTEGRATION ON PRODUCT DEVELOPMENT ... 8 6...58 12. SUMMARY OF HETEROGENEOUS INTEGRATION TECHNIQUES........................... 63 13. HETEROGENEOUS INTEGRATION PRODUCT EXAMPLES

  4. Integrated care

    PubMed Central

    Gröne, Oliver; Garcia-Barbero, Mila

    2001-01-01

    Abstract The WHO European Office for Integrated Health Care Services in Barcelona is an integral part of the World Health Organizations' Regional Office for Europe. The main purpose of the Barcelona office is within the integration of services to encourage and facilitate changes in health care services in order to promote health and improve management and patient satisfaction by working for quality, accessibility, cost-effectiveness and participation. This position paper outlines the need for Integrated Care from a European perspective, provides a theoretical framework for the meaning of Integrated Care and its strategies and summarizes the programmes of the office that will support countries in the WHO European Region to improve health services. PMID:16896400

  5. Improving integration for integrated coastal zone management: an eight country study.

    PubMed

    Portman, M E; Esteves, L S; Le, X Q; Khan, A Z

    2012-11-15

    Integrated coastal zone management (ICZM) is a widely accepted approach for sustainable management of the coastal environment. ICZM emphasizes integration across sectors, levels of government, uses, stakeholders, and spatial and temporal scales. While improving integration is central to progress in ICZM, the role of and the achievement of integration remain understudied. To further study these two points, our research analyzes the performance of specific mechanisms used to support ICZM in eight countries (Belgium, India, Israel, Italy, Portugal, Sweden, UK, and Vietnam). The assessment is based on a qualitative comparative analysis conducted through the use of two surveys. It focuses on five ICZM mechanisms (environmental impact assessment; planning hierarchy; setback lines; marine spatial planning, and regulatory commission) and their role in improving integration. Our findings indicate that certain mechanisms enhance specific types of integration more effectively than others. Environmental impact assessment enhances science-policy integration and can be useful to integrate knowledge across sectors. Planning hierarchy and regulatory commissions are effective mechanisms to integrate policies across government levels, with the latter also promoting public-government integration. Setback lines can be applied to enhance integration across landscape units. Marine spatial planning is a multi-faceted mechanism with the potential to promote all types of integration. Policy-makers should adopt the mechanisms that are suited to the type of integration needed. Results of this study also contribute to evidence-based coastal management by identifying the most common impediments related to the mechanisms of integration in the eight studied countries. Copyright © 2012 Elsevier B.V. All rights reserved.

  6. Measuring the degree of integration for an integrated service network

    PubMed Central

    Ye, Chenglin; Browne, Gina; Grdisa, Valerie S; Beyene, Joseph; Thabane, Lehana

    2012-01-01

    Background Integration involves the coordination of services provided by autonomous agencies and improves the organization and delivery of multiple services for target patients. Current measures generally do not distinguish between agencies’ perception and expectation. We propose a method for quantifying the agencies’ service integration. Using the data from the Children’s Treatment Network (CTN), we aimed to measure the degree of integration for the CTN agencies in York and Simcoe. Theory and methods We quantified the integration by the agreement between perceived and expected levels of involvement and calculated four scores from different perspectives for each agency. We used the average score to measure the global network integration and examined the sensitivity of the global score. Results Most agencies’ integration scores were <65%. As measured by the agreement between every other agency’s perception and expectation, the overall integration of CTN in Simcoe and York was 44% (95% CI: 39%–49%) and 52% (95% CI: 48%–56%), respectively. The sensitivity analysis showed that the global scores were robust. Conclusion Our method extends existing measures of integration and possesses a good extent of validity. We can also apply the method in monitoring improvement and linking integration with other outcomes. PMID:23593050

  7. Functional Integration

    NASA Astrophysics Data System (ADS)

    Cartier, Pierre; DeWitt-Morette, Cecile

    2006-11-01

    Acknowledgements; List symbols, conventions, and formulary; Part I. The Physical and Mathematical Environment: 1. The physical and mathematical environment; Part II. Quantum Mechanics: 2. First lesson: gaussian integrals; 3. Selected examples; 4. Semiclassical expansion: WKB; 5. Semiclassical expansion: beyond WKB; 6. Quantum dynamics: path integrals and operator formalism; Part III. Methods from Differential Geometry: 7. Symmetries; 8. Homotopy; 9. Grassmann analysis: basics; 10. Grassmann analysis: applications; 11. Volume elements, divergences, gradients; Part IV. Non-Gaussian Applications: 12. Poisson processes in physics; 13. A mathematical theory of Poisson processes; 14. First exit time: energy problems; Part V. Problems in Quantum Field Theory: 15. Renormalization 1: an introduction; 16. Renormalization 2: scaling; 17. Renormalization 3: combinatorics; 18. Volume elements in quantum field theory Bryce DeWitt; Part VI. Projects: 19. Projects; Appendix A. Forward and backward integrals: spaces of pointed paths; Appendix B. Product integrals; Appendix C. A compendium of gaussian integrals; Appendix D. Wick calculus Alexander Wurm; Appendix E. The Jacobi operator; Appendix F. Change of variables of integration; Appendix G. Analytic properties of covariances; Appendix H. Feynman's checkerboard; Bibliography; Index.

  8. Functional Integration

    NASA Astrophysics Data System (ADS)

    Cartier, Pierre; DeWitt-Morette, Cecile

    2010-06-01

    Acknowledgements; List symbols, conventions, and formulary; Part I. The Physical and Mathematical Environment: 1. The physical and mathematical environment; Part II. Quantum Mechanics: 2. First lesson: gaussian integrals; 3. Selected examples; 4. Semiclassical expansion: WKB; 5. Semiclassical expansion: beyond WKB; 6. Quantum dynamics: path integrals and operator formalism; Part III. Methods from Differential Geometry: 7. Symmetries; 8. Homotopy; 9. Grassmann analysis: basics; 10. Grassmann analysis: applications; 11. Volume elements, divergences, gradients; Part IV. Non-Gaussian Applications: 12. Poisson processes in physics; 13. A mathematical theory of Poisson processes; 14. First exit time: energy problems; Part V. Problems in Quantum Field Theory: 15. Renormalization 1: an introduction; 16. Renormalization 2: scaling; 17. Renormalization 3: combinatorics; 18. Volume elements in quantum field theory Bryce DeWitt; Part VI. Projects: 19. Projects; Appendix A. Forward and backward integrals: spaces of pointed paths; Appendix B. Product integrals; Appendix C. A compendium of gaussian integrals; Appendix D. Wick calculus Alexander Wurm; Appendix E. The Jacobi operator; Appendix F. Change of variables of integration; Appendix G. Analytic properties of covariances; Appendix H. Feynman's checkerboard; Bibliography; Index.

  9. Teaching Integrity

    ERIC Educational Resources Information Center

    Saunders, Sue; Butts, Jennifer Lease

    2011-01-01

    Integrity is one of those essential yet highly ambiguous concepts. For the purpose of this chapter, integrity is defined as that combination of both attributes and actions that makes entities appear to be whole and ethical, as well as consistent. Like the concepts of leadership or wisdom or community or collaboration, integrity is a key element of…

  10. Curriculum: To Integrate or Not To Integrate.

    ERIC Educational Resources Information Center

    Miller, Kathleen A.

    Teachers who use cooperative, integrated methods will produce students more competent in problem solving techniques, communicating effectively, and working cooperatively with others. Benefits of an integrated curriculum include: (1) reaching students with different learning types; (2) developing critical and divergent thinking skills in students;…

  11. AN INTEGRATED PERSPECTIVE ON THE ASSESSMENT OF TECHNOLOGIES: INTEGRATE-HTA.

    PubMed

    Wahlster, Philip; Brereton, Louise; Burns, Jacob; Hofmann, Björn; Mozygemba, Kati; Oortwijn, Wija; Pfadenhauer, Lisa; Polus, Stephanie; Rehfuess, Eva; Schilling, Imke; van der Wilt, Gert Jan; Gerhardus, Ansgar

    2017-01-01

    Current health technology assessment (HTA) is not well equipped to assess complex technologies as insufficient attention is being paid to the diversity in patient characteristics and preferences, context, and implementation. Strategies to integrate these and several other aspects, such as ethical considerations, in a comprehensive assessment are missing. The aim of the European research project INTEGRATE-HTA was to develop a model for an integrated HTA of complex technologies. A multi-method, four-stage approach guided the development of the INTEGRATE-HTA Model: (i) definition of the different dimensions of information to be integrated, (ii) literature review of existing methods for integration, (iii) adjustment of concepts and methods for assessing distinct aspects of complex technologies in the frame of an integrated process, and (iv) application of the model in a case study and subsequent revisions. The INTEGRATE-HTA Model consists of five steps, each involving stakeholders: (i) definition of the technology and the objective of the HTA; (ii) development of a logic model to provide a structured overview of the technology and the system in which it is embedded; (iii) evidence assessment on effectiveness, economic, ethical, legal, and socio-cultural aspects, taking variability of participants, context, implementation issues, and their interactions into account; (iv) populating the logic model with the data generated in step 3; (v) structured process of decision-making. The INTEGRATE-HTA Model provides a structured process for integrated HTAs of complex technologies. Stakeholder involvement in all steps is essential as a means of ensuring relevance and meaningful interpretation of the evidence.

  12. 76 FR 64082 - Combined Notice of Filings #1

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-17

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Combined Notice of Filings 1 Take notice...-000. Applicants: Agua Caliente Solar, LLC. Description: Agua Caliente Solar, LLC Notice of Self... effective 9/12/2011. Filed Date: 10/04/2011. Accession Number: 20111004-5178. Comment Date: 5 p.m. Eastern...

  13. Malaria transmission in two localities in north-western Argentina

    PubMed Central

    Dantur Juri, María J; Zaidenberg, Mario; Claps, Guillermo L; Santana, Mirta; Almirón, Walter R

    2009-01-01

    Background Malaria is one of the most important tropical diseases that affects people globally. The influence of environmental conditions in the patterns of temporal distribution of malaria vectors and the disease has been studied in different countries. In the present study, ecological aspects of the malaria vector Anopheles (Anopheles) pseudopunctipennis and their relationship with climatic variables, as well as the seasonality of malaria cases, were studied in two localities, El Oculto and Aguas Blancas, in north-western Argentina. Methods The fluctuation of An. pseudopunctipennis and the malaria cases distribution was analysed with Random Effect Poisson Regression. This analysis takes into account the effect of each climatic variable on the abundance of both vector and malaria cases, giving as results predicted values named Incidence Rate Radio. Results The number of specimens collected in El Oculto and Aguas Blancas was 4224 (88.07%) and 572 (11.93%), respectively. In El Oculto no marked seasonality was found, different from Aguas Blancas, where high abundance was detected at the end of spring and the beginning of summer. The maximum mean temperature affected the An. pseudopunctipennis fluctuation in El Oculto and Aguas Blancas. When considering the relationship between the number of malaria cases and the climatic variables in El Oculto, maximum mean temperature and accumulated rainfall were significant, in contrast with Aguas Blancas, where mean temperature and humidity showed a closer relationship to the fluctuation in the disease. Conclusion The temporal distribution patterns of An. pseudopunctipennis vary in both localities, but spring appears as the season with better conditions for mosquito development. Maximum mean temperature was the most important variable in both localities. Malaria cases were influenced by the maximum mean temperature in El Oculto, while the mean temperature and humidity were significant in Aguas Blancas. In Aguas Blancas peaks of

  14. Misconceptions and Integration.

    PubMed

    Mortaz Hejri, Sara; Mirzazadeh, Azim; Jalili, Mohammad

    2015-10-01

    Pervasive beliefs regarding curricular reform and integration have flourished among medical students, faculty members and medical school administrators. These concepts have extensively impacted the reform process, sometimes by resisting the reforms and sometimes by diverting the curriculum from its planned objectives. In the current paper, we have tried to address the challenges of integration in MD program by looking at the existing literature and the experience of the international universities. We collected the questions frequently asked during the curricular reform process. We, then, evaluated them, and selected 5 main ideas. In order to find their answers, we searched the literature using these keywords: integration, reform, and undergraduate medical curriculum. The findings are discussed in five sections: 1) Reform is not equivalent to integration, 2) Integration can be implemented in both high school and graduate programs, 3) Organ-system based integration is not the only method available for integration, 4) Integration of two phases (basic sciences and physiopathology) can be considered but it is not mandatory, 5) Integration does not fade basic sciences in favor of clinical courses. It seems that medical education literature and prior experience of the leading universities do not support most of the usual concepts about integration. Therefore, it is important to consider informed decision making based on best evidence rather than personal opinions during the curricular reform process.

  15. Shared or Integrated: Which Type of Integration is More Effective Improves Students’ Creativity?

    NASA Astrophysics Data System (ADS)

    Mariyam, M.; Kaniawati, I.; Sriyati, S.

    2017-09-01

    Integrated science learning has various types of integration. This study aims to apply shared and integrated type of integration with project based learning (PjBL) model to improve students’ creativity on waste recycling theme. The research method used is a quasi experiment with the matching-only pre test-post test design. The samples of this study are 108 students consisting of 36 students (experiment class 1st), 35 students (experiment class 2nd) and 37 students (control class 3rd) at one of Junior High School in Tanggamus, Lampung. The results show that there is difference of creativity improvement in the class applied by PjBL model with shared type of integration, integrated type of integration and without any integration in waste recycling theme. Class applied by PjBL model with shared type of integration has the higher creativity improvement than the PjBL model with integrated type of integration and without any integration. Integrated science learning using shared type only combines 2 lessons, hence an intact concept is resulted. So, PjBL model with shared type of integration more effective improves students’ creativity than integrated type.

  16. Integration

    ERIC Educational Resources Information Center

    Kalyn, Brenda

    2006-01-01

    Integrated learning is an exciting adventure for both teachers and students. It is not uncommon to observe the integration of academic subjects such as math, science, and language arts. However, educators need to recognize that movement experiences in physical education also can be linked to academic curricula and, may even lead the…

  17. Retroviral DNA Integration Directed by HIV Integration Protein in Vitro

    NASA Astrophysics Data System (ADS)

    Bushman, Frederic D.; Fujiwara, Tamio; Craigie, Robert

    1990-09-01

    Efficient retroviral growth requires integration of a DNA copy of the viral RNA genome into a chromosome of the host. As a first step in analyzing the mechanism of integration of human immunodeficiency virus (HIV) DNA, a cell-free system was established that models the integration reaction. The in vitro system depends on the HIV integration (IN) protein, which was partially purified from insect cells engineered to express IN protein in large quantities. Integration was detected in a biological assay that scores the insertion of a linear DNA containing HIV terminal sequences into a λ DNA target. Some integration products generated in this assay contained five-base pair duplications of the target DNA at the recombination junctions, a characteristic of HIV integration in vivo; the remaining products contained aberrant junctional sequences that may have been produced in a variation of the normal reaction. These results indicate that HIV IN protein is the only viral protein required to insert model HIV DNA sequences into a target DNA in vitro.

  18. Photonic Integrated Circuits

    NASA Technical Reports Server (NTRS)

    Krainak, Michael; Merritt, Scott

    2016-01-01

    Integrated photonics generally is the integration of multiple lithographically defined photonic and electronic components and devices (e.g. lasers, detectors, waveguides passive structures, modulators, electronic control and optical interconnects) on a single platform with nanometer-scale feature sizes. The development of photonic integrated circuits permits size, weight, power and cost reductions for spacecraft microprocessors, optical communication, processor buses, advanced data processing, and integrated optic science instrument optical systems, subsystems and components. This is particularly critical for small spacecraft platforms. We will give an overview of some NASA applications for integrated photonics.

  19. Tackling community integration in mental health home visit integration in Finland.

    PubMed

    Raitakari, Suvi; Haahtela, Riikka; Juhila, Kirsi

    2016-09-01

    Integration - and its synonym inclusion - is emphasised in the western welfare states and in the European Union in particular. Integration is also a central topic in the social sciences and in current mental health and homelessness research and practice. As mental healthcare has shifted from psychiatric hospitals to the community, it has inevitably become involved with housing and integration issues. This article explores how community integration is understood and tackled in mental health floating support services (FSSs) and, more precisely, in service user-practitioner home visit interaction. The aim, through shedding light on how the idea of integration is present and discussed in front-line mental health practices, is to offer a 'template' on how we might, in a systematic and reflective way, develop community integration research and practice. The analysis is based on ethnomethodological and micro-sociological interaction research. The research settings are two FSSs located in a large Finnish city. The data contain 24 audio-recorded and transcribed home visits conducted in 2011 and 2012 with 16 different service users. The study shows how the participants in service user-practitioner interaction give meaning to community integration and make decisions about how it should (or should not) be enhanced in each individual case. This activity is called community integration work in action. Community integration work in action is based on various dimensions of integration: getting out of the house, participating in group activities and getting along with those involved in one's life and working life. Additionally, the analysis demonstrates how community integration work is accomplished by discursive devices (resistance, positioning, excuses and justifications, delicacy and advice-giving). The article concludes that community integration is about interaction: it is not only service users' individual challenge but also a social challenge, our challenge. © 2015 John

  20. Feedback Integrators

    NASA Astrophysics Data System (ADS)

    Chang, Dong Eui; Jiménez, Fernando; Perlmutter, Matthew

    2016-12-01

    A new method is proposed to numerically integrate a dynamical system on a manifold such that the trajectory stably remains on the manifold and preserves the first integrals of the system. The idea is that given an initial point in the manifold we extend the dynamics from the manifold to its ambient Euclidean space and then modify the dynamics outside the intersection of the manifold and the level sets of the first integrals containing the initial point such that the intersection becomes a unique local attractor of the resultant dynamics. While the modified dynamics theoretically produces the same trajectory as the original dynamics, it yields a numerical trajectory that stably remains on the manifold and preserves the first integrals. The big merit of our method is that the modified dynamics can be integrated with any ordinary numerical integrator such as Euler or Runge-Kutta. We illustrate this method by applying it to three famous problems: the free rigid body, the Kepler problem and a perturbed Kepler problem with rotational symmetry. We also carry out simulation studies to demonstrate the excellence of our method and make comparisons with the standard projection method, a splitting method and Störmer-Verlet schemes.

  1. Conceptualizing and measuring integration: findings from the health systems integration study.

    PubMed

    Gillies, R R; Shortell, S M; Anderson, D A; Mitchell, J B; Morgan, K L

    1993-01-01

    Given the pressures for health care reform, interest in the concept of integrated or organized delivery systems as a means to offer more coordinated cost-effective care is growing. This article has two primary objectives: (1) to clarify the different types of integration associated with the notion of an organized delivery system, and (2) to share the results from an ongoing study of 12 organized delivery systems. The findings indicate a moderate level of integration overall, particularly in the areas of culture, financial planning, and strategic planning. The study found that corporate staff respondents perceive their systems to be more integrated and effective than do operating unit managers, and that some functional integration areas are positively associated with both physician-system and clinical integration that, in turn, are positively related to each other. Overall, perceived integration was found to be positively associated with perceived effectiveness.

  2. Sensitivity Studies Using Multi-Region and Open Boundary Conditions for Terrain Bottom-Following Ocean Models

    DTIC Science & Technology

    2003-03-01

    Vol. 5, No. 1, 31-40, 1982. Fiuza, A. F. de G., Hidrologia e Dinamica das Aguas Costeiras de Portugal. Dissertacao apresentada a Universidade de...Upwelling: Its Sediment Record, part A, pp 85-97, Plenum, New York, 1983. Fiuza, A. F. G., Hidrologia e Dinamica das Aguas Costeiras de Portugal

  3. Integration: For or Against?

    ERIC Educational Resources Information Center

    Veblen, Kari K.; Elliott, David J.

    2000-01-01

    Argues in support of integrating music education with other subject areas, discussing the importance of maintaining music's integrity, combining the arts, reasons for integration, and whether integration is always good. Offers an opposing argument that views the integration of music with other subject areas as unsound. (CMK)

  4. A participatory approach to integrated aquifer management: The case of Guanajuato State, Mexico

    NASA Astrophysics Data System (ADS)

    Sandoval, Ricardo

    de l'État s'est appliqué à développer une stratégie sur deux plans. Tout d'abord, des études hydrogéologiques de base et des modèles mathématiques d'écoulement et de transport de nappe ont été réalisés à partir d'un suivi d'ensemble des puits existants et d'une révision générale du contexte géologique de l'État. Ensuite, on a soutenu une structure de participation des usagers de l'eau aux actions de gestion de l'eau, à partir de la dissémination de l'information pour la mise en place de projets pilotes efficaces d'utilisation de l'eau, avec des aides financières, techniques et politiques de l'État. Simultanément, un effort coordonné en vue de l'achèvement de l'enregistrement des usagers de l'eau a été fait avec l'autorité fédérale, en même temps que d'autres mesures de soutien, telles que des programmes de formation et des campagnes de surveillance. Cet article présente une vue d'ensemble des réalisations de projets et des défis. Resumen El Estado de Guanajuato, situado en el centro de México, ocupa menos del 2% de la superficie del país. Tiene casi 17.000 pozos profundos, de los cuales se extrae cerca de 4.000 hm3/a, lo que supone un exceso de 1.000 hm3/a respecto a la recarga anual. Puesto que el agua es administrada a nivel federal en México, el gobierno del Estado afronta el reto de asegurar el desarrollo de la población sin disponer de medios formales de intervención. Dadas las limitaciones para aplicar políticas y medidas reguladoras, el programa del agua en el Estado tiene como objetivo principal la implantación de una doble estrategia. Por un lado, desarrollar estudios hidrogeológicos básicos y modelos matemáticos de flujo y transporte de los acuíferos, basándose en una campaña exhaustiva de pozos existentes y en una revisión del marco geológico del Estado. Por otro lado, promover-con soporte financiero, técnico y político-una estructura de participación de los usuarios en las acciones de gesti

  5. Boolean integral calculus

    NASA Technical Reports Server (NTRS)

    Tucker, Jerry H.; Tapia, Moiez A.; Bennett, A. Wayne

    1988-01-01

    The concept of Boolean integration is developed, and different Boolean integral operators are introduced. Given the changes in a desired function in terms of the changes in its arguments, the ways of 'integrating' (i.e. realizing) such a function, if it exists, are presented. The necessary and sufficient conditions for integrating, in different senses, the expression specifying the changes are obtained. Boolean calculus has applications in the design of logic circuits and in fault analysis.

  6. ESIF Call for High-Impact Integrated Projects | Energy Systems Integration

    Science.gov Websites

    Integrated Projects As a U.S. Department of Energy user facility, the Energy Systems Integration Facility concepts, tools, and technologies needed to measure, analyze, predict, protect, and control the grid of the Facility | NREL ESIF Call for High-Impact Integrated Projects ESIF Call for High-Impact

  7. In situ enzyme aided adsorption of soluble xylan biopolymers onto cellulosic material.

    PubMed

    Chimphango, Annie F A; Görgens, J F; van Zyl, W H

    2016-06-05

    The functional properties of cellulose fibers can be modified by adsorption of xylan biopolymers. The adsorption is improved when the degree of biopolymers substitution with arabinose and 4-O-methyl-glucuronic acid (MeGlcA) side groups, is reduced. α-l-Arabinofuranosidase (AbfB) and α-d-glucuronidase (AguA) enzymes were applied for side group removal, to increase adsorption of xylan from sugarcane (Saccharum officinarum L) bagasse (BH), bamboo (Bambusa balcooa) (BM), Pinus patula (PP) and Eucalyptus grandis (EH) onto cotton lint. The AguA treatment increased the adsorption of all xylans by up to 334%, whereas, the AbfB increased the adsorption of the BM and PP by 31% and 44%, respectively. A combination of AguA and AbfB treatment increased the adsorption, but to a lesser extent than achieved with AguA treatment. This indicated that the removal of the glucuronic acid side groups provided the most significant increase in xylan adsorption to cellulose, in particular through enzymatic treatment. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Spatial-Temporal Distribution of Hantavirus Rodent-Borne Infection by Oligoryzomys fulvescens in the Agua Buena Region - Panama

    PubMed Central

    Gonzalez, Publio; Cumbrera, Alberto; Rivero, Alina; Avila, Mario; Armién, Aníbal G.; Koster, Frederick; Glass, Gregory

    2016-01-01

    Background Hotspot detection and characterization has played an increasing role in understanding the maintenance and transmission of zoonotic pathogens. Identifying the specific environmental factors (or their correlates) that influence reservoir host abundance help increase understanding of how pathogens are maintained in natural systems and are crucial to identifying disease risk. However, most recent studies are performed at macro-scale and describe broad temporal patterns of population abundances. Few have been conducted at a microscale over short time periods that better capture the dynamical patterns of key populations. These finer resolution studies may better define the likelihood of local pathogen persistence. This study characterizes the landscape distribution and spatio-temporal dynamics of Oligoryzomys fulvescens (O. fulvescens), an important mammalian reservoir in Central America. Methods Information collected in a longitudinal study of rodent populations in the community of Agua Buena in Tonosí, Panama, between April 2006 and December 2009 was analyzed using non-spatial analyses (box plots) and explicit spatial statistical tests (correlograms, SADIE and LISA). A 90 node grid was built (raster format) to design a base map. The area between the nodes was 0.09 km2 and the total study area was 6.43 km2 (2.39 x 2.69 km). The temporal assessment dataset was divided into four periods for each year studied: the dry season, rainy season, and two months-long transitions between seasons (the months of April and December). Results There were heterogeneous patterns in the population densities and degrees of dispersion of O. fulvescens that varied across seasons and among years. The species typically was locally absent during the late transitional months of the season, and re-established locally in subsequent years. These populations re-occurred in the same area during the first three years but subsequently re-established further south in the final year of the

  9. Spatial-Temporal Distribution of Hantavirus Rodent-Borne Infection by Oligoryzomys fulvescens in the Agua Buena Region--Panama.

    PubMed

    Armién, Blas; Ortiz, Paulo Lazaro; Gonzalez, Publio; Cumbrera, Alberto; Rivero, Alina; Avila, Mario; Armién, Aníbal G; Koster, Frederick; Glass, Gregory

    2016-02-01

    Hotspot detection and characterization has played an increasing role in understanding the maintenance and transmission of zoonotic pathogens. Identifying the specific environmental factors (or their correlates) that influence reservoir host abundance help increase understanding of how pathogens are maintained in natural systems and are crucial to identifying disease risk. However, most recent studies are performed at macro-scale and describe broad temporal patterns of population abundances. Few have been conducted at a microscale over short time periods that better capture the dynamical patterns of key populations. These finer resolution studies may better define the likelihood of local pathogen persistence. This study characterizes the landscape distribution and spatio-temporal dynamics of Oligoryzomys fulvescens (O. fulvescens), an important mammalian reservoir in Central America. Information collected in a longitudinal study of rodent populations in the community of Agua Buena in Tonosí, Panama, between April 2006 and December 2009 was analyzed using non-spatial analyses (box plots) and explicit spatial statistical tests (correlograms, SADIE and LISA). A 90 node grid was built (raster format) to design a base map. The area between the nodes was 0.09 km(2) and the total study area was 6.43 km(2) (2.39 x 2.69 km). The temporal assessment dataset was divided into four periods for each year studied: the dry season, rainy season, and two months-long transitions between seasons (the months of April and December). There were heterogeneous patterns in the population densities and degrees of dispersion of O. fulvescens that varied across seasons and among years. The species typically was locally absent during the late transitional months of the season, and re-established locally in subsequent years. These populations re-occurred in the same area during the first three years but subsequently re-established further south in the final year of the study. Spatial

  10. Plan for a groundwater monitoring network in Taiwan

    NASA Astrophysics Data System (ADS)

    Hsu, Shiang-Kueen

    In Taiwan, rapid economic growth, rising standards of living, and an altered societal structure have in recent years put severe demands on water supplies. Because of its stable quantity and quality, groundwater has long been a reliable source of water for domestic, agricultural, and industrial users, but the establishment of a management program that integrates groundwater and surface-water use has been hampered by the lack of groundwater data. In 1992, the Department of Water Resources (DWR) initiated a program entitled "Groundwater Monitoring Network Plan in Taiwan." Under this program, basic groundwater data, including water-level and water-quality data, are being collected, and a reliable database is being established for the purpose of managing total water resources. This paper introduces the goals, implementation stages, and scope of that plan. The plan calls for constructing 517 hydrogeologic survey stations and 990 groundwater monitoring wells within 17 years. Under this program, water-level fluctuations are continuously monitored, whereas water-quality samples are taken for analysis only at the initial drilling stage and, subsequently, at the time when a monitoring well is being serviced. In 1996, the DWR and the Water Resources Planning Commission were merged to form today's Water Resources Bureau. Résumé A Taïwan, l'expansion économique rapide, l'amélioration des conditions de vie et la transformation de la structure sociale ont provoqué, ces dernières années, une très forte demande en eau. Du fait de sa constance en qualité et en quantité, l'eau souterraine a longtemps été considérée comme une ressource en eau sûre pour les usages domestiques, agricoles et industriels. Mais la mise en place d'un programme de gestion intégrant les utilisations d'eaux souterraines et de surface a été gênée par l'absence de données sur les eaux souterraines. En 1992, le Département des Ressources en Eau a lancé le programme "Plan pour un réseau de

  11. Faces of integration.

    PubMed

    Williams, Paul; Sullivan, Helen

    2009-12-22

    Two central themes permeate this paper-the interplay between structure and agency in integration processes and the extent to which this is mediated through sensemaking by individual actors. The empirical base for the paper is provided by case study research from Wales which draws on examples of different types of integration in health and social care. The individual case studies highlight different interpretations of integration set against a background of the resources involved, processes employed and outcomes achieved. A wide ranging discussion exposes the complex interplay and dynamics between structural factors and the manner in which they enable or constrain integration, and individual actors realising their potential agency through leadership, professionalism and boundary spanning to influence outcomes. The importance of structure and agency complementing each other to determine effective integration is emphasised, together with the scope that is available for interpretation and meaning by individual actors within the contested discourse of integration.

  12. Faces of integration

    PubMed Central

    Williams, Paul; Sullivan, Helen

    2009-01-01

    Theme Two central themes permeate this paper—the interplay between structure and agency in integration processes and the extent to which this is mediated through sensemaking by individual actors. Case study The empirical base for the paper is provided by case study research from Wales which draws on examples of different types of integration in health and social care. The individual case studies highlight different interpretations of integration set against a background of the resources involved, processes employed and outcomes achieved. Discussion A wide ranging discussion exposes the complex interplay and dynamics between structural factors and the manner in which they enable or constrain integration, and individual actors realising their potential agency through leadership, professionalism and boundary spanning to influence outcomes. The importance of structure and agency complementing each other to determine effective integration is emphasised, together with the scope that is available for interpretation and meaning by individual actors within the contested discourse of integration. PMID:20087420

  13. Integrals and integral equations in linearized wing theory

    NASA Technical Reports Server (NTRS)

    Lomax, Harvard; Heaslet, Max A; Fuller, Franklyn B

    1951-01-01

    The formulas of subsonic and supersonic wing theory for source, doublet, and vortex distributions are reviewed and a systematic presentation is provided which relates these distributions to the pressure and to the vertical induced velocity in the plane of the wing. It is shown that care must be used in treating the singularities involved in the analysis and that the order of integration is not always reversible. Concepts suggested by the irreversibility of order of integration are shown to be useful in the inversion of singular integral equations when operational techniques are used. A number of examples are given to illustrate the methods presented, attention being directed to supersonic flight speed.

  14. Integrative structure modeling with the Integrative Modeling Platform.

    PubMed

    Webb, Benjamin; Viswanath, Shruthi; Bonomi, Massimiliano; Pellarin, Riccardo; Greenberg, Charles H; Saltzberg, Daniel; Sali, Andrej

    2018-01-01

    Building models of a biological system that are consistent with the myriad data available is one of the key challenges in biology. Modeling the structure and dynamics of macromolecular assemblies, for example, can give insights into how biological systems work, evolved, might be controlled, and even designed. Integrative structure modeling casts the building of structural models as a computational optimization problem, for which information about the assembly is encoded into a scoring function that evaluates candidate models. Here, we describe our open source software suite for integrative structure modeling, Integrative Modeling Platform (https://integrativemodeling.org), and demonstrate its use. © 2017 The Protein Society.

  15. Imagery Integration Team

    NASA Technical Reports Server (NTRS)

    Calhoun, Tracy; Melendrez, Dave

    2014-01-01

    The Human Exploration Science Office (KX) provides leadership for NASA's Imagery Integration (Integration 2) Team, an affiliation of experts in the use of engineering-class imagery intended to monitor the performance of launch vehicles and crewed spacecraft in flight. Typical engineering imagery assessments include studying and characterizing the liftoff and ascent debris environments; launch vehicle and propulsion element performance; in-flight activities; and entry, landing, and recovery operations. Integration 2 support has been provided not only for U.S. Government spaceflight (e.g., Space Shuttle, Ares I-X) but also for commercial launch providers, such as Space Exploration Technologies Corporation (SpaceX) and Orbital Sciences Corporation, servicing the International Space Station. The NASA Integration 2 Team is composed of imagery integration specialists from JSC, the Marshall Space Flight Center (MSFC), and the Kennedy Space Center (KSC), who have access to a vast pool of experience and capabilities related to program integration, deployment and management of imagery assets, imagery data management, and photogrammetric analysis. The Integration 2 team is currently providing integration services to commercial demonstration flights, Exploration Flight Test-1 (EFT-1), and the Space Launch System (SLS)-based Exploration Missions (EM)-1 and EM-2. EM-2 will be the first attempt to fly a piloted mission with the Orion spacecraft. The Integration 2 Team provides the customer (both commercial and Government) with access to a wide array of imagery options - ground-based, airborne, seaborne, or vehicle-based - that are available through the Government and commercial vendors. The team guides the customer in assembling the appropriate complement of imagery acquisition assets at the customer's facilities, minimizing costs associated with market research and the risk of purchasing inadequate assets. The NASA Integration 2 capability simplifies the process of securing one

  16. Multistep integration formulas for the numerical integration of the satellite problem

    NASA Technical Reports Server (NTRS)

    Lundberg, J. B.; Tapley, B. D.

    1981-01-01

    The use of two Class 2/fixed mesh/fixed order/multistep integration packages of the PECE type for the numerical integration of the second order, nonlinear, ordinary differential equation of the satellite orbit problem. These two methods are referred to as the general and the second sum formulations. The derivation of the basic equations which characterize each formulation and the role of the basic equations in the PECE algorithm are discussed. Possible starting procedures are examined which may be used to supply the initial set of values required by the fixed mesh/multistep integrators. The results of the general and second sum integrators are compared to the results of various fixed step and variable step integrators.

  17. Energy Systems Integration News | Energy Systems Integration Facility |

    Science.gov Websites

    -matter experts to develop cyber-physical systems security testing methodologies and resilience best the Energy Systems Integration Facility as part of NREL's work with SolarCity and the Hawaiian Electric Companies. Photo by Amy Glickson, NREL Welcome to Energy Systems Integration News, NREL's monthly

  18. Integrable cosmological potentials

    NASA Astrophysics Data System (ADS)

    Sokolov, V. V.; Sorin, A. S.

    2017-09-01

    The problem of classification of the Einstein-Friedman cosmological Hamiltonians H with a single scalar inflaton field φ, which possess an additional integral of motion polynomial in momenta on the shell of the Friedman constraint H=0, is considered. Necessary and sufficient conditions for the existence of the first-, second- and third-degree integrals are derived. These conditions have the form of ODEs for the cosmological potential V(φ). In the case of linear and quadratic integrals we find general solutions of the ODEs and construct the corresponding integrals explicitly. A new wide class of Hamiltonians that possess a cubic integral is derived. The corresponding potentials are represented in parametric form in terms of the associated Legendre functions. Six families of special elementary solutions are described, and sporadic superintegrable cases are discussed.

  19. Relation of streams, lakes, and wetlands to groundwater flow systems

    NASA Astrophysics Data System (ADS)

    Winter, Thomas C.

    Surface-water bodies are integral parts of groundwater flow systems. Groundwater interacts with surface water in nearly all landscapes, ranging from small streams, lakes, and wetlands in headwater areas to major river valleys and seacoasts. Although it generally is assumed that topographically high areas are groundwater recharge areas and topographically low areas are groundwater discharge areas, this is true primarily for regional flow systems. The superposition of local flow systems associated with surface-water bodies on this regional framework results in complex interactions between groundwater and surface water in all landscapes, regardless of regional topographic position. Hydrologic processes associated with the surface-water bodies themselves, such as seasonally high surface-water levels and evaporation and transpiration of groundwater from around the perimeter of surface-water bodies, are a major cause of the complex and seasonally dynamic groundwater flow fields associated with surface water. These processes have been documented at research sites in glacial, dune, coastal, mantled karst, and riverine terrains. Résumé Les eaux de surface sont parties intégrantes des systèmes aquifères. Les eaux souterraines interagissent avec les eaux de surface dans presque tous les types d'environnements, depuis les petits ruisseaux, les lacs et les zones humides jusqu'aux bassins versants des vallées des grands fleuves et aux lignes de côte. Il est en général admis que les zones topographiquement hautes sont des lieux de recharge des aquifères et les zones basses des lieux de décharge, ce qui est le cas des grands systèmes aquifères régionaux. La superposition de systèmes locaux, associés à des eaux de surface, à l'organisation régionale d'écoulements souterrains résulte d'interactions complexes entre les eaux souterraines et les eaux de surface dans tous les environnements, quelle que soit la situation topographique régionale. Les processus

  20. The Vehicle Integrated Performance Analysis Experience: Reconnecting With Technical Integration

    NASA Technical Reports Server (NTRS)

    McGhee, D. S.

    2006-01-01

    Very early in the Space Launch Initiative program, a small team of engineers at MSFC proposed a process for performing system-level assessments of a launch vehicle. Aimed primarily at providing insight and making NASA a smart buyer, the Vehicle Integrated Performance Analysis (VIPA) team was created. The difference between the VIPA effort and previous integration attempts is that VIPA a process using experienced people from various disciplines, which focuses them on a technically integrated assessment. The foundations of VIPA s process are described. The VIPA team also recognized the need to target early detailed analysis toward identifying significant systems issues. This process is driven by the T-model for technical integration. VIPA s approach to performing system-level technical integration is discussed in detail. The VIPA process significantly enhances the development and monitoring of realizable project requirements. VIPA s assessment validates the concept s stated performance, identifies significant issues either with the concept or the requirements, and then reintegrates these issues to determine impacts. This process is discussed along with a description of how it may be integrated into a program s insight and review process. The VIPA process has gained favor with both engineering and project organizations for being responsive and insightful

  1. Using laboratory flow experiments and reactive chemical transport modeling for designing waterflooding of the Agua Fria Reservoir, Poza Rica-Altamira Field, Mexico

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Birkle, P.; Pruess, K.; Xu, T.

    Waterflooding for enhanced oil recovery requires that injected waters must be chemically compatible with connate reservoir waters, in order to avoid mineral dissolution-and-precipitation cycles that could seriously degrade formation permeability and injectivity. Formation plugging is a concern especially in reservoirs with a large content of carbonates, such as calcite and dolomite, as such minerals typically react rapidly with an aqueous phase, and have strongly temperature-dependent solubility. Clay swelling can also pose problems. During a preliminary waterflooding pilot project, the Poza Rica-Altamira oil field, bordering the Gulf coast in the eastern part of Mexico, experienced injectivity loss after five months ofmore » reinjection of formation waters into well AF-847 in 1999. Acidizing with HCl restored injectivity. We report on laboratory experiments and reactive chemistry modeling studies that were undertaken in preparation for long-term waterflooding at Agua Frma. Using analogous core plugs obtained from the same reservoir interval, laboratory coreflood experiments were conducted to examine sensitivity of mineral dissolution and precipitation effects to water composition. Native reservoir water, chemically altered waters, and distilled water were used, and temporal changes in core permeability, mineral abundances and aqueous concentrations of solutes were monitored. The experiments were simulated with the multi-phase, nonisothermal reactive transport code TOUGHREACT, and reasonable to good agreement was obtained for changes in solute concentrations. Clay swelling caused an additional impact on permeability behavior during coreflood experiments, whereas the modeled permeability depends exclusively on chemical processes. TOUGHREACT was then used for reservoir-scale simulation of injecting ambient-temperature water (30 C, 86 F) into a reservoir with initial temperature of 80 C (176 F). Untreated native reservoir water was found to cause serious porosity

  2. A Comprehensive Theory of Integration.

    PubMed

    Singer, Sara J; Kerrissey, Michaela; Friedberg, Mark; Phillips, Russell

    2018-03-01

    Efforts to transform health care delivery to improve care have increasingly focused on care integration. However, variation in how integration is defined has complicated efforts to design, synthesize, and compare studies of integration in health care. Evaluations of integration initiatives would be enhanced by describing them according to clear definitions of integration and specifying which empirical relationships they seek to test-whether among types of integration or between integration and outcomes of care. Drawing on previous work, we present a comprehensive theoretical model of relationships between types of integration and propose how to measure them.

  3. Streamlining Payload Integration

    NASA Technical Reports Server (NTRS)

    Lufkin, Susan N.

    2010-01-01

    Payload integration onto space transport vehicles and the International Space Station (ISS) is a complex process. Yet, cargo transport is the sole reason for any space mission, be it for ferrying humans, science, or hardware. As the largest such effort in history, the ISS offers a wide variety of payload experience. However, for any payload to reach the Space Station under the current process, Payload Developers face a list of daunting tasks that go well beyond just designing the payload to the constraints of the transport vehicle and its stowage topology. Payload customers are required to prove their payload s functionality, structural integrity, and safe integration - including under less than nominal situations. They must also plan for or provide training, procedures, hardware labeling, ground support, and communications. In addition, they must deal with negotiating shared consumables, integrating software, obtaining video, and coordinating the return of data and hardware. All the while, they must meet export laws, launch schedules, budget limits, and the consensus of more than 12 panel and board reviews. Despite the cost and infrastructure overhead, payload proposals have increased. Just in the span from FY08 to FY09, the NASA Payload Space Station Support Office budget rose from $78M to $96M in attempt to manage the growing manifest, but the potential number of payloads still exceeds available Payload Integration Management manpower. The growth has also increased management difficulties due to the fact that payloads are more frequently added to a flight schedule late in the flow. The current standard ISS template for payload integration from concept to payload turn-over is 36 months, or 18 months if the payload already has a preliminary design. Customers are increasingly requiring a turn-around of 3 to 6-months to meet market needs. The following paper suggests options for streamlining the current payload integration process in order to meet customer schedule

  4. Collinear facilitation and contour integration in autism: evidence for atypical visual integration.

    PubMed

    Jachim, Stephen; Warren, Paul A; McLoughlin, Niall; Gowen, Emma

    2015-01-01

    Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interaction, atypical communication and a restricted repertoire of interests and activities. Altered sensory and perceptual experiences are also common, and a notable perceptual difference between individuals with ASD and controls is their superior performance in visual tasks where it may be beneficial to ignore global context. This superiority may be the result of atypical integrative processing. To explore this claim we investigated visual integration in adults with ASD (diagnosed with Asperger's Syndrome) using two psychophysical tasks thought to rely on integrative processing-collinear facilitation and contour integration. We measured collinear facilitation at different flanker orientation offsets and contour integration for both open and closed contours. Our results indicate that compared to matched controls, ASD participants show (i) reduced collinear facilitation, despite equivalent performance without flankers; and (ii) less benefit from closed contours in contour integration. These results indicate weaker visuospatial integration in adults with ASD and suggest that further studies using these types of paradigms would provide knowledge on how contextual processing is altered in ASD.

  5. Integrated Learning

    ERIC Educational Resources Information Center

    Gnanakan, Ken

    2012-01-01

    This book upholds the idea of learning and education as a means to individual development and social empowerment. It presents a holistic picture, looking at learning as an integral part of one's social and physical life. Strongly differing from existing classroom perspectives, the book analyses integrated learning at its broadest possible…

  6. Integrated Networks.

    ERIC Educational Resources Information Center

    Robinovitz, Stewart

    1987-01-01

    A strategy for integrated data and voice networks implemented at the University of Michigan is described. These networks often use multi-technologies, multi-vendors, and multi-transmission media that will be fused into a single integrated network. Transmission media include twisted-pair wire, coaxial cable, fiber optics, and microwave. (Author/MLW)

  7. Integrative Education.

    ERIC Educational Resources Information Center

    Walker, Dean

    1995-01-01

    In contrast with subject-bound education, integrative education promotes the construction of broad "mental programs" that require students to use skills and information in new, realistic contexts. Early childhood education has long been a model of integrative education, emphasizing the whole child and offering a wide range of experiences that…

  8. Understanding integrated care: a comprehensive conceptual framework based on the integrative functions of primary care

    PubMed Central

    Valentijn, Pim P.; Schepman, Sanneke M.; Opheij, Wilfrid; Bruijnzeels, Marc A.

    2013-01-01

    Introduction Primary care has a central role in integrating care within a health system. However, conceptual ambiguity regarding integrated care hampers a systematic understanding. This paper proposes a conceptual framework that combines the concepts of primary care and integrated care, in order to understand the complexity of integrated care. Methods The search method involved a combination of electronic database searches, hand searches of reference lists (snowball method) and contacting researchers in the field. The process of synthesizing the literature was iterative, to relate the concepts of primary care and integrated care. First, we identified the general principles of primary care and integrated care. Second, we connected the dimensions of integrated care and the principles of primary care. Finally, to improve content validity we held several meetings with researchers in the field to develop and refine our conceptual framework. Results The conceptual framework combines the functions of primary care with the dimensions of integrated care. Person-focused and population-based care serve as guiding principles for achieving integration across the care continuum. Integration plays complementary roles on the micro (clinical integration), meso (professional and organisational integration) and macro (system integration) level. Functional and normative integration ensure connectivity between the levels. Discussion The presented conceptual framework is a first step to achieve a better understanding of the inter-relationships among the dimensions of integrated care from a primary care perspective. PMID:23687482

  9. Understanding integrated care: a comprehensive conceptual framework based on the integrative functions of primary care.

    PubMed

    Valentijn, Pim P; Schepman, Sanneke M; Opheij, Wilfrid; Bruijnzeels, Marc A

    2013-01-01

    Primary care has a central role in integrating care within a health system. However, conceptual ambiguity regarding integrated care hampers a systematic understanding. This paper proposes a conceptual framework that combines the concepts of primary care and integrated care, in order to understand the complexity of integrated care. The search method involved a combination of electronic database searches, hand searches of reference lists (snowball method) and contacting researchers in the field. The process of synthesizing the literature was iterative, to relate the concepts of primary care and integrated care. First, we identified the general principles of primary care and integrated care. Second, we connected the dimensions of integrated care and the principles of primary care. Finally, to improve content validity we held several meetings with researchers in the field to develop and refine our conceptual framework. The conceptual framework combines the functions of primary care with the dimensions of integrated care. Person-focused and population-based care serve as guiding principles for achieving integration across the care continuum. Integration plays complementary roles on the micro (clinical integration), meso (professional and organisational integration) and macro (system integration) level. Functional and normative integration ensure connectivity between the levels. The presented conceptual framework is a first step to achieve a better understanding of the inter-relationships among the dimensions of integrated care from a primary care perspective.

  10. RIPE integrity primitives, part 2 (RACE Integrity Primitives Evaluation)

    NASA Astrophysics Data System (ADS)

    Denboer, B.; Boly, J. P.; Bosselaers, A.; Brandt, J.; Chaum, D.; Damgaard, I.; Dichtl, M.; Fumy, W.; Vanderham, M.; Jansen, C. J. A.

    1993-04-01

    A manual intended for those seeking to secure information systems by applying modern cryptography is presented. It represents the successful attainment of goals by RIPE (RACE (Research and development of Advanced Communications technology in Europe) Integrity Primitives Evaluation). The recommended portfolio of integrity primitives, which is the main product of the project, forms the heart of the manual. By integrity, is meant the kinds of security that can be achieved through cryptography, apart from keeping messages secret. Thus included are ways to ensure that stored or communicated data is not illicitly modified, that parties exchanging messages are actually present, and that 'signed' electronic messages can be recognized as authentic by anyone. Of particular concern to the project were the high speed requirements of broadband communication. The project also aimed for completeness in its recommendations. As a result, the portfolio contains primitives, that is building blocks, that can meet most of today's perceived needs for integrity.

  11. RIPE integrity primitives, part 1 (RACE Integrity Primitives Evaluation)

    NASA Astrophysics Data System (ADS)

    Denboer, B.; Boly, J. P.; Bosselaers, A.; Brandt, J.; Chaum, D.; Damgaard, I.; Dichtl, M.; Fumy, W.; Vanderham, M.; Jansen, C. J. A.

    1993-04-01

    A manual intended for those seeking to secure information systems by applying modern cryptography is presented. It represents the successful attainment of goals by RIPE (RACE (Research and development of Advanced Communication technology in Europe) Integrity Primitives Evaluation). The recommended portfolio of integrity primitives, which is the main product of the project, forms the heart of the manual. By integrity, is meant the kinds of security that can be achieved through cryptography, apart from keeping messages secret. Thus included are ways to ensure that stored or communicated data is not illicitly modified, that parties exchanging messages are actually present, and that 'signed' electronic messages can be recognized as authentic by anyone. Of particular concern to the project were the high speed requirements of broadband communication. The project also aimed for completeness in its recommendations. As a result, the portfolio contains primitives, that is building blocks, that can meet most of today's perceived needs for integrity.

  12. The staircase method: integrals for periodic reductions of integrable lattice equations

    NASA Astrophysics Data System (ADS)

    van der Kamp, Peter H.; Quispel, G. R. W.

    2010-11-01

    We show, in full generality, that the staircase method (Papageorgiou et al 1990 Phys. Lett. A 147 106-14, Quispel et al 1991 Physica A 173 243-66) provides integrals for mappings, and correspondences, obtained as traveling wave reductions of (systems of) integrable partial difference equations. We apply the staircase method to a variety of equations, including the Korteweg-De Vries equation, the five-point Bruschi-Calogero-Droghei equation, the quotient-difference (QD)-algorithm and the Boussinesq system. We show that, in all these cases, if the staircase method provides r integrals for an n-dimensional mapping, with 2r, then one can introduce q <= 2r variables, which reduce the dimension of the mapping from n to q. These dimension-reducing variables are obtained as joint invariants of k-symmetries of the mappings. Our results support the idea that often the staircase method provides sufficiently many integrals for the periodic reductions of integrable lattice equations to be completely integrable. We also study reductions on other quad-graphs than the regular {\\ Z}^2 lattice, and we prove linear growth of the multi-valuedness of iterates of high-dimensional correspondences obtained as reductions of the QD-algorithm.

  13. Integrated stationary Ornstein-Uhlenbeck process, and double integral processes

    NASA Astrophysics Data System (ADS)

    Abundo, Mario; Pirozzi, Enrica

    2018-03-01

    We find a representation of the integral of the stationary Ornstein-Uhlenbeck (ISOU) process in terms of Brownian motion Bt; moreover, we show that, under certain conditions on the functions f and g , the double integral process (DIP) D(t) = ∫βt g(s) (∫αs f(u) dBu) ds can be thought as the integral of a suitable Gauss-Markov process. Some theoretical and application details are given, among them we provide a simulation formula based on that representation by which sample paths, probability densities and first passage times of the ISOU process are obtained; the first-passage times of the DIP are also studied.

  14. Choosing the Right Systems Integration

    NASA Astrophysics Data System (ADS)

    Péči, Matúš; Važan, Pavel

    2014-12-01

    The paper examines systems integration and its main levels at higher levels of control. At present, the systems integration is one of the main aspects participating in the consolidation processes and financial flows of a company. Systems Integration is a complicated emotionconsuming process and it is often a problem to choose the right approach and level of integration. The research focused on four levels of integration, while each of them is characterized by specific conditions. At each level, there is a summary of recommendations and practical experience. The paper also discusses systems integration between the information and MES levels. The main part includes user-level integration where we describe an example of such integration. Finally, we list recommendations and also possible predictions of the systems integration as one of the important factors in the future.

  15. Integration Becoming Business: Marketisation of Integration Training for Immigrants

    ERIC Educational Resources Information Center

    Kurki, Tuuli; Masoud, Ameera; Niemi, Anna-Maija; Brunila, Kristiina

    2018-01-01

    Today, education is massively affected by marketisation and the drastic demands of the global economy. Integration training for immigrants has fallen prey to that; immigrants are employed to serve market needs, which has been attributed to the creation of "integration as business." In the article, the authors examine how integration…

  16. Research environments that promote integrity.

    PubMed

    Jeffers, Brenda Recchia; Whittemore, Robin

    2005-01-01

    The body of empirical knowledge about research integrity and the factors that promote research integrity in nursing research environments remains small. To propose an internal control model as an innovative framework for the design and structure of nursing research environments that promote integrity. An internal control model is adapted to illustrate its use for conceptualizing and designing research environments that promote integrity. The internal control model integrates both the organizational elements necessary to promote research integrity and the processes needed to assess research environments. The model provides five interrelated process components within which any number of research integrity variables and processes may be used and studied: internal control environment, risk assessment, internal control activities, monitoring, and information and communication. The components of the proposed research integrity internal control model proposed comprise an integrated conceptualization of the processes that provide reasonable assurance that research integrity will be promoted within the nursing research environment. Schools of nursing can use the model to design, implement, and evaluate systems that promote research integrity. The model process components need further exploration to substantiate the use of the model in nursing research environments.

  17. Integrating data to acquire new knowledge: Three modes of integration in plant science.

    PubMed

    Leonelli, Sabina

    2013-12-01

    This paper discusses what it means and what it takes to integrate data in order to acquire new knowledge about biological entities and processes. Maureen O'Malley and Orkun Soyer have pointed to the scientific work involved in data integration as important and distinct from the work required by other forms of integration, such as methodological and explanatory integration, which have been more successful in captivating the attention of philosophers of science. Here I explore what data integration involves in more detail and with a focus on the role of data-sharing tools, like online databases, in facilitating this process; and I point to the philosophical implications of focusing on data as a unit of analysis. I then analyse three cases of data integration in the field of plant science, each of which highlights a different mode of integration: (1) inter-level integration, which involves data documenting different features of the same species, aims to acquire an interdisciplinary understanding of organisms as complex wholes and is exemplified by research on Arabidopsis thaliana; (2) cross-species integration, which involves data acquired on different species, aims to understand plant biology in all its different manifestations and is exemplified by research on Miscanthus giganteus; and (3) translational integration, which involves data acquired from sources within as well as outside academia, aims at the provision of interventions to improve human health (e.g. by sustaining the environment in which humans thrive) and is exemplified by research on Phytophtora ramorum. Recognising the differences between these efforts sheds light on the dynamics and diverse outcomes of data dissemination and integrative research; and the relations between the social and institutional roles of science, the development of data-sharing infrastructures and the production of scientific knowledge. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Integrating Academic Integrity Education with the Business Law Course: Why and How?

    ERIC Educational Resources Information Center

    McGill, Shelley

    2008-01-01

    This article advocates integrating academic integrity education into the business law course. Many have suggested teaching business ethics this way but have ignored the natural overlap in legal content with the traditional business law course. This article focuses on why and how business law instructors should integrate the two. Rather than…

  19. Identification of the putrescine biosynthetic genes in Pseudomonas aeruginosa and characterization of agmatine deiminase and N-carbamoylputrescine amidohydrolase of the arginine decarboxylase pathway.

    PubMed

    Nakada, Yuji; Itoh, Yoshifumi

    2003-03-01

    Putrescine can be synthesized either directly from ornithine by ornithine decarboxylase (ODC; the speC product) or indirectly from arginine via arginine decarboxylase (ADC; the speA product). The authors identified the speA and speC genes in Pseudomonas aeruginosa PAO1. The activities of the two decarboxylases were similar and each enzyme alone appeared to direct sufficient formation of the polyamine for normal growth. A mutant defective in both speA and speC was a putrescine auxotroph. In this strain, agmatine deiminase (the aguA product) and N-carbamoylputrescine amidohydrolase (the aguB product), which were initially identified as the catabolic enzymes of agmatine, biosynthetically convert agmatine to putrescine in the ADC pathway: a double mutant of aguAB and speC was a putrescine auxotroph. AguA was purified as a homodimer of 43 kDa subunits and AguB as a homohexamer of 33 kDa subunits. AguA specifically deiminated agmatine with K(m) and K(cat) values of 0.6 mM and 4.2 s(-1), respectively. AguB was specific to N-carbamoylputrescine and the K(m) and K(cat) values of the enzyme for the substrate were 0.5 mM and 3.3 s(-1), respectively. Whereas AguA has no structural relationship to any known C-N hydrolases, AguB is a protein of the nitrilase family that performs thiol-assisted catalysis. Inhibition by SH reagents and the conserved cysteine residue in AguA and its homologues suggested that this enzyme is also involved in thiol-mediated catalysis.

  20. Abuse notation of improper integrals

    NASA Astrophysics Data System (ADS)

    Arfi, E.; Wiryanto, L. H.

    2018-01-01

    In the definition of \\int_ab {f(x)dx} , it was assumed that the interval [a, b] was finite. However, in many application in physics, engineering, economics, and probability we wish to allow a or b (or both) to be infinite or for the other case when f has an infinite discontinuity in [a, b]. In either case the integral is called improper integral. Definition of improper integral is the limit of a definite integral as an endpoint of the interval of integration approaches either a specified real number or ∞ or -∞ or, in some cases, as both endpoints approach limits. Many of the first-year students in ITERA learning about improper integrals make an abuse notation like written improper integral just like standard definite integral. Based on this situation, we tried to change the habits of the students in the writing of improper integrals by providing sufficient understanding and considerable exercises. It turns out this way gives good result, based on the percentage of the value of the midterms to the problem of improper integrals give a fairly good percentage value.

  1. Elliptic polylogarithms and iterated integrals on elliptic curves. II. An application to the sunrise integral

    NASA Astrophysics Data System (ADS)

    Broedel, Johannes; Duhr, Claude; Dulat, Falko; Tancredi, Lorenzo

    2018-06-01

    We introduce a class of iterated integrals that generalize multiple polylogarithms to elliptic curves. These elliptic multiple polylogarithms are closely related to similar functions defined in pure mathematics and string theory. We then focus on the equal-mass and non-equal-mass sunrise integrals, and we develop a formalism that enables us to compute these Feynman integrals in terms of our iterated integrals on elliptic curves. The key idea is to use integration-by-parts identities to identify a set of integral kernels, whose precise form is determined by the branch points of the integral in question. These kernels allow us to express all iterated integrals on an elliptic curve in terms of them. The flexibility of our approach leads us to expect that it will be applicable to a large variety of integrals in high-energy physics.

  2. Hospital-Physician Collaboration: Landscape of Economic Integration and Impact on Clinical Integration

    PubMed Central

    Burns, Lawton Robert; Muller, Ralph W

    2008-01-01

    Context Hospital-physician relationships (HPRs) are an important area of academic research, given their impact on hospitals' financial success. HPRs also are at the center of several federal policy proposals such as gain sharing, bundled payments, and pay-for-performance (P4P). Methods This article analyzes the HPRs that focus on the economic integration of hospitals and physicians and the goals that HPRs are designed to achieve. It then reviews the literature on the impact of HPRs on cost, quality, and clinical integration. Findings The goals of the two parties in HPRs overlap only partly, and their primary aim is not reducing cost or improving quality. The evidence base for the impact of many models of economic integration is either weak or nonexistent, with only a few models of economic integration having robust effects. The relationship between economic and clinical integration also is weak and inconsistent. There are several possible reasons for this weak linkage and many barriers to further integration between hospitals and physicians. Conclusions Successful HPRs may require better financial conditions for physicians, internal changes to clinical operations, application of behavioral skills to the management of HPRs, changes in how providers are paid, and systemic changes encompassing several types of integration simultaneously. PMID:18798884

  3. Critical perspectives of pedagogical approaches to reversing the order of integration in double integrals

    NASA Astrophysics Data System (ADS)

    Tisdell, Christopher C.

    2017-11-01

    This paper presents some critical perspectives regarding pedagogical approaches to the method of reversing the order of integration in double integrals from prevailing educational literature on multivariable calculus. First, we question the message found in popular textbooks that the traditional process of reversing the order of integration is necessary when solving well-known problems. Second, we illustrate that the method of integration by parts can be directly applied to many of the classic pedagogical problems in the literature concerning double integrals, without taking the well-worn steps associated with reversing the order of integration. Third, we examine the benefits and limitations of such a method. In our conclusion, we advocate for integration by parts to be a part of the pedagogical conversation in the learning and teaching of double integral methods; and call for more debate around its use in the learning and teaching of other areas of mathematics. Finally, we emphasize the need for critical approaches in the pedagogy of mathematics more broadly.

  4. Retroviral DNA Integration

    PubMed Central

    2016-01-01

    The integration of a DNA copy of the viral RNA genome into host chromatin is the defining step of retroviral replication. This enzymatic process is catalyzed by the virus-encoded integrase protein, which is conserved among retroviruses and LTR-retrotransposons. Retroviral integration proceeds via two integrase activities: 3′-processing of the viral DNA ends, followed by the strand transfer of the processed ends into host cell chromosomal DNA. Herein we review the molecular mechanism of retroviral DNA integration, with an emphasis on reaction chemistries and architectures of the nucleoprotein complexes involved. We additionally discuss the latest advances on anti-integrase drug development for the treatment of AIDS and the utility of integrating retroviral vectors in gene therapy applications. PMID:27198982

  5. 4 pitfalls to clinical integration.

    PubMed

    Redding, John

    2012-11-01

    Four common mistakes can easily thwart clinical integration: Assuming that EHR adoption is the cornerstone of successful integration; Delaying the development of ambulatory services that support clinical integration; Believing that knowledge of clinical integration initiatives will passively diffuse through the ranks; Attaching too much weight to Federal Trade Commission/Department of Justice approval of a clinical integration model.

  6. New Challenges in Information Integration

    NASA Astrophysics Data System (ADS)

    Haas, Laura M.; Soffer, Aya

    Information integration is the cornerstone of modern business informatics. It is a pervasive problem; rarely is a new application built without an initial phase of gathering and integrating information. Information integration comes in a wide variety of forms. Historically, two major approaches were recognized: data federation and data warehousing. Today, we need new approaches, as information integration becomes more dynamic, while coping with growing volumes of increasingly dirty and diverse data. At the same time, information integration must be coupled more tightly with the applications and the analytics that will leverage the integrated results, to make the integration process more tractable and the results more consumable.

  7. Effect of dimer dissociation on activity and thermostability of the alpha-glucuronidase from Geobacillus stearothermophilus: dissecting the different oligomeric forms of family 67 glycoside hydrolases.

    PubMed

    Shallom, Dalia; Golan, Gali; Shoham, Gil; Shoham, Yuval

    2004-10-01

    The oligomeric organization of enzymes plays an important role in many biological processes, such as allosteric regulation, conformational stability and thermal stability. alpha-Glucuronidases are family 67 glycosidases that cleave the alpha-1,2-glycosidic bond between 4-O-methyl-D-glucuronic acid and xylose units as part of an array of hemicellulose-hydrolyzing enzymes. Currently, two crystal structures of alpha-glucuronidases are available, those from Geobacillus stearothermophilus (AguA) and from Cellvibrio japonicus (GlcA67A). Both enzymes are homodimeric, but surprisingly their dimeric organization is different, raising questions regarding the significance of dimerization for the enzymes' activity and stability. Structural comparison of the two enzymes suggests several elements that are responsible for the different dimerization organization. Phylogenetic analysis shows that the alpha-glucuronidases AguA and GlcA67A can be classified into two distinct subfamilies of bacterial alpha-glucuronidases, where the dimer-forming residues of each enzyme are conserved only within its own subfamily. It seems that the different dimeric forms of AguA and GlcA67A represent the two alternative dimeric organizations of these subfamilies. To study the biological significance of the dimerization in alpha-glucuronidases, we have constructed a monomeric form of AguA by mutating three of its interface residues (W328E, R329T, and R665N). The activity of the monomer was significantly lower than the activity of the wild-type dimeric AguA, and the optimal temperature for activity of the monomer was around 35 degrees C, compared to 65 degrees C of the wild-type enzyme. Nevertheless, the melting temperature of the monomeric protein, 72.9 degrees C, was almost identical to that of the wild-type, 73.4 degrees C. It appears that the dimerization of AguA is essential for efficient catalysis and that the dissociation into monomers results in subtle conformational changes in the structure

  8. Effect of Dimer Dissociation on Activity and Thermostability of the α-Glucuronidase from Geobacillus stearothermophilus: Dissecting the Different Oligomeric Forms of Family 67 Glycoside Hydrolases

    PubMed Central

    Shallom, Dalia; Golan, Gali; Shoham, Gil; Shoham, Yuval

    2004-01-01

    The oligomeric organization of enzymes plays an important role in many biological processes, such as allosteric regulation, conformational stability and thermal stability. α-Glucuronidases are family 67 glycosidases that cleave the α-1,2-glycosidic bond between 4-O-methyl-d-glucuronic acid and xylose units as part of an array of hemicellulose-hydrolyzing enzymes. Currently, two crystal structures of α-glucuronidases are available, those from Geobacillus stearothermophilus (AguA) and from Cellvibrio japonicus (GlcA67A). Both enzymes are homodimeric, but surprisingly their dimeric organization is different, raising questions regarding the significance of dimerization for the enzymes' activity and stability. Structural comparison of the two enzymes suggests several elements that are responsible for the different dimerization organization. Phylogenetic analysis shows that the α-glucuronidases AguA and GlcA67A can be classified into two distinct subfamilies of bacterial α-glucuronidases, where the dimer-forming residues of each enzyme are conserved only within its own subfamily. It seems that the different dimeric forms of AguA and GlcA67A represent the two alternative dimeric organizations of these subfamilies. To study the biological significance of the dimerization in α-glucuronidases, we have constructed a monomeric form of AguA by mutating three of its interface residues (W328E, R329T, and R665N). The activity of the monomer was significantly lower than the activity of the wild-type dimeric AguA, and the optimal temperature for activity of the monomer was around 35°C, compared to 65°C of the wild-type enzyme. Nevertheless, the melting temperature of the monomeric protein, 72.9°C, was almost identical to that of the wild-type, 73.4°C. It appears that the dimerization of AguA is essential for efficient catalysis and that the dissociation into monomers results in subtle conformational changes in the structure which indirectly influence the active site region

  9. Geology, geochemistry, geochronology, and economic potential of Neogene volcanic rocks in the Laguna Pedernal and Salar de Aguas Calientes segments of the Archibarca lineament, northwest Argentina

    NASA Astrophysics Data System (ADS)

    Richards, J. P.; Jourdan, F.; Creaser, R. A.; Maldonado, G.; DuFrane, S. A.

    2013-05-01

    This study presents new geochemical, geochronological, isotopic, and mineralogical data, combined with new geological mapping for a 2400 km2 area of Neogene volcanic rocks in northwestern Argentina near the border with Chile, between 25°10‧S and 25°45‧S. The area covers the zone of intersection between the main axis of the Cordillera Occidental and a set of NW-SE-trending structures that form part of the transverse Archibarca lineament. This lineament has localized major ore deposits in Chile (e.g., the late Eocene La Escondida porphyry Cu deposit) and large volcanic centers such as the active Llullaillaco and Lastarría volcanoes on the border between Chile and Argentina, and the Neogene Archibarca, Antofalla, and Cerro Galán volcanoes in Argentina. Neogene volcanic rocks in the Laguna Pedernal and Salar de Aguas Calientes areas are mostly high-K calc-alkaline in composition, and range from basaltic andesites, through andesites and dacites, to rhyolites. Magmatic temperatures and oxidation states, estimated from mineral compositions, range from ~ 1000 °C and ∆FMQ ≈ 1.0-1.5 in andesites, to ~ 850 °C and ∆FMQ ≈ 1.5-2.0 in dacites and rhyolites. The oldest rocks consist of early-middle Miocene andesite-dacite plagioclase-pyroxene-phyric lava flows and ignimbrites, with 40Ar/39Ar ages ranging from 17.14 ± 0.10 Ma to 11.76 ± 0.27 Ma. Their major and trace element compositions are typical of the Andean Central Volcanic Zone, and show strong crustal contamination trends for highly incompatible elements such as Cs, Rb, Th, and U. These rocks are geochemically grouped as sub-suite 1. This widespread intermediate composition volcanism was followed in the middle-late Miocene by a period of more focused rhyodacitic flow-dome complex formation. These felsic rocks are characterized by less extreme enrichments in highly incompatible elements, and increasing depletion of heavy rare earth elements. These rocks are geochemically grouped as sub-suite 2. The

  10. Integrated optics technology study

    NASA Technical Reports Server (NTRS)

    Chen, B.; Findakly, T.; Innarella, R.

    1982-01-01

    The status and near term potential of materials and processes available for the fabrication of single mode integrated electro-optical components are discussed. Issues discussed are host material and orientation, waveguide formation, optical loss mechanisms, wavelength selection, polarization effects and control, laser to integrated optics coupling fiber optic waveguides to integrated optics coupling, sources, and detectors. Recommendations of the best materials, technology, and processes for fabrication of integrated optical components for communications and fiber gyro applications are given.

  11. Integration of virtual and real scenes within an integral 3D imaging environment

    NASA Astrophysics Data System (ADS)

    Ren, Jinsong; Aggoun, Amar; McCormick, Malcolm

    2002-11-01

    The Imaging Technologies group at De Montfort University has developed an integral 3D imaging system, which is seen as the most likely vehicle for 3D television avoiding psychological effects. To create real fascinating three-dimensional television programs, a virtual studio that performs the task of generating, editing and integrating the 3D contents involving virtual and real scenes is required. The paper presents, for the first time, the procedures, factors and methods of integrating computer-generated virtual scenes with real objects captured using the 3D integral imaging camera system. The method of computer generation of 3D integral images, where the lens array is modelled instead of the physical camera is described. In the model each micro-lens that captures different elemental images of the virtual scene is treated as an extended pinhole camera. An integration process named integrated rendering is illustrated. Detailed discussion and deep investigation are focused on depth extraction from captured integral 3D images. The depth calculation method from the disparity and the multiple baseline method that is used to improve the precision of depth estimation are also presented. The concept of colour SSD and its further improvement in the precision is proposed and verified.

  12. Measuring integrated care.

    PubMed

    Strandberg-Larsen, Martin

    2011-02-01

    The positive outcomes of coordination of healthcare services are to an increasing extent becoming clear. However the complexity of the field is an inhibiting factor for vigorously designed trial studies. Conceptual clarity and a consistent theoretical frame-work are thus needed. While researchers respond to these needs, patients and providers face the multiple challenges of today's healthcare environment. Decision makers, planners and managers need evidence based policy options and information on the scope of the integrated care challenges they are facing. The US managed care organization Kaiser Permanente has been put forward as an example for European healthcare systems to follow, although the evidence base is far from conclusive. The thesis has five objectives: 1) To contribute to the understanding of the concept of integration in healthcare systems and to identify measurement methods to capture the multi-dimensional aspects of integrated healthcare delivery. 2) To assess the level of integration of the Danish healthcare system. 3) To assess the use of joint health plans as a tool for coordination between the regional and local level in the Danish healthcare system. 4) To compare the inputs and performance of the Danish healthcare system and the managed care organization Kaiser Permanente, California, US. 5) To compare primary care clinicians' perception of clinical integration in two healthcare systems: Kaiser Permanente, Northern California and the Danish healthcare system. Further to examine the associations between specific organizational factors and clinical integration within each system. The literature was systematically searched to identify methods for measurement of integrated healthcare delivery. A national cross-sectional survey was conducted among major professional stake-holders at five different levels of the Danish healthcare system. The survey data were used to allow for analysis of the level of integration achieved. Data from the survey were

  13. Understanding Care Integration from the Ground Up: Five Organizing Constructs that Shape Integrated Practices.

    PubMed

    Cohen, Deborah J; Balasubramanian, Bijal A; Davis, Melinda; Hall, Jennifer; Gunn, Rose; Stange, Kurt C; Green, Larry A; Miller, William L; Crabtree, Benjamin F; England, Mary Jane; Clark, Khaya; Miller, Benjamin F

    2015-01-01

    To provide empirical evidence on key organizing constructs shaping practical, real-world integration of behavior health and primary care to comprehensively address patients' medical, emotional, and behavioral health needs. In a comparative case study using an immersion-crystallization approach, a multidisciplinary team analyzed data from observations of practice operations, interviews, and surveys of practice members, and implementation diaries. Practices were drawn from 2 studies of practices attempting to integrate behavioral health and primary care: Advancing Care Together, a demonstration project of 11 practices located in Colorado, and the Integration Workforce Study, a study of 8 practices across the United States. We identified 5 key organizing constructs influencing integration of primary care and behavioral health: 1) Integration REACH (the extent to which the integration program was delivered to the identified target population), 2) establishment of continuum of care pathways addressing the location of care across the range of patient's severity of illness, 3) approach to patient transitions: referrals or warm handoffs, 4) location of the integration workforce, and 5) participants' mental model for integration. These constructs intertwine within an organization's historic and social context to produce locally adapted approaches to integrating care. Contextual factors, particularly practice type, influenced whether specialty mental health and substance use services were colocated within an organization. Interaction among 5 organizing constructs and practice context produces diverse expressions of integrated care. These constructs provide a framework for understanding how primary care and behavioral health services can be integrated in routine practice. © Copyright 2015 by the American Board of Family Medicine.

  14. Line integral on engineering mathematics

    NASA Astrophysics Data System (ADS)

    Wiryanto, L. H.

    2018-01-01

    Definite integral is a basic material in studying mathematics. At the level of calculus, calculating of definite integral is based on fundamental theorem of calculus, related to anti-derivative, as the inverse operation of derivative. At the higher level such as engineering mathematics, the definite integral is used as one of the calculating tools of line integral. the purpose of this is to identify if there is a question related to line integral, we can use definite integral as one of the calculating experience. The conclusion of this research says that the teaching experience in introducing the relation between both integrals through the engineer way of thinking can motivate and improve students in understanding the material.

  15. ELECTRONIC INTEGRATING CIRCUIT

    DOEpatents

    Englemann, R.H.

    1963-08-20

    An electronic integrating circuit using a transistor with a capacitor connected between the emitter and collector through which the capacitor discharges at a rate proportional to the input current at the base is described. Means are provided for biasing the base with an operating bias and for applying a voltage pulse to the capacitor for charging to an initial voltage. A current dividing diode is connected between the base and emitter of the transistor, and signal input terminal means are coupled to the juncture of the capacitor and emitter and to the base of the transistor. At the end of the integration period, the residual voltage on said capacitor is less by an amount proportional to the integral of the input signal. Either continuous or intermittent periods of integration are provided. (AEC)

  16. Integrated diagnostics

    NASA Technical Reports Server (NTRS)

    Hunthausen, Roger J.

    1988-01-01

    Recently completed projects in which advanced diagnostic concepts were explored and/or demonstrated are summarized. The projects begin with the design of integrated diagnostics for the Army's new gas turbine engines, and advance to the application of integrated diagnostics to other aircraft subsystems. Finally, a recent project is discussed which ties together subsystem fault monitoring and diagnostics with a more complete picture of flight domain knowledge.

  17. Integrated optics technology study

    NASA Technical Reports Server (NTRS)

    Chen, B.

    1982-01-01

    The materials and processes available for the fabrication of single mode integrated electrooptical components are described. Issues included in the study are: (1) host material and orientation, (2) waveguide formation, (3) optical loss mechanisms, (4) wavelength selection, (5) polarization effects and control, (6) laser to integrated optics coupling,(7) fiber optic waveguides to integrated optics coupling, (8) souces, (9) detectors. The best materials, technology and processes for fabrication of integrated optical components for communications and fiber gyro applications are recommended.

  18. Social Integration and Divorce.

    ERIC Educational Resources Information Center

    Booth, Alan; And Others

    1991-01-01

    Longitudinal data on over 1,300 married persons suggest that divorce was deterred by absence of divorce in reference group (normative integration) and was deterred for shorter marriages by more friends and organizational affiliations (communicative integration). Sharing friends and organization affiliations with spouse (functional integration) may…

  19. Strategic Integration: The Practical Politics of Integrated Research in Context

    ERIC Educational Resources Information Center

    van Kerkhoff, Lorrae

    2005-01-01

    Designing an integrative research program requires that research leaders negotiate a balance between the scientific interest of research and the practical interests of non-scientific partners. This paper examines the ways integrated research is formally categorised, and analyses the tangible expressions of the practical politics involved in…

  20. Human-technology Integration

    NASA Astrophysics Data System (ADS)

    Mullen, Katharine M.

    Human-technology integration is the replacement of human parts and extension of human capabilities with engineered devices and substrates. Its result is hybrid biological-artificial systems. We discuss here four categories of products furthering human-technology integration: wearable computers, pervasive computing environments, engineered tissues and organs, and prosthetics, and introduce examples of currently realized systems in each category. We then note that realization of a completely artificial sytem via the path of human-technology integration presents the prospect of empirical confirmation of an aware artificially embodied system.

  1. Perceptual integration without conscious access

    PubMed Central

    van Leeuwen, Jonathan; Olivers, Christian N. L.

    2017-01-01

    The visual system has the remarkable ability to integrate fragmentary visual input into a perceptually organized collection of surfaces and objects, a process we refer to as perceptual integration. Despite a long tradition of perception research, it is not known whether access to consciousness is required to complete perceptual integration. To investigate this question, we manipulated access to consciousness using the attentional blink. We show that, behaviorally, the attentional blink impairs conscious decisions about the presence of integrated surface structure from fragmented input. However, despite conscious access being impaired, the ability to decode the presence of integrated percepts remains intact, as shown through multivariate classification analyses of electroencephalogram (EEG) data. In contrast, when disrupting perception through masking, decisions about integrated percepts and decoding of integrated percepts are impaired in tandem, while leaving feedforward representations intact. Together, these data show that access consciousness and perceptual integration can be dissociated. PMID:28325878

  2. CopperCore Service Integration

    ERIC Educational Resources Information Center

    Vogten, Hubert; Martens, Harrie; Nadolski, Rob; Tattersall, Colin; van Rosmalen, Peter; Koper, Rob

    2007-01-01

    In an e-learning environment there is a need to integrate various e-learning services like assessment services, collaboration services, learning design services and communication services. In this article we present the design and implementation of a generic integrative service framework, called CopperCore Service Integration (CCSI). We will…

  3. Curriculum Integration: An Overview

    ERIC Educational Resources Information Center

    Wall, Amanda; Leckie, Alisa

    2017-01-01

    Curriculum integration is a tenet of middle level education. "This We Believe," the position paper of the Association for Middle Level Education, advocates for curriculum that is exploratory, relevant, integrative, and meaningful for young adolescents. Teachers can integrate curriculum across content areas by anchoring units of study in…

  4. Design of integrated laser initiator

    NASA Astrophysics Data System (ADS)

    Cao, Chunqiang; He, Aifeng; Jing, Bo; Ma, Yue

    2018-03-01

    This paper analyzes the design principle of integrated laser detonator, introduces the design method of integrated laser Detonators. Based on the integrated laser detonator, structure, laser energy -exchange device, circuit design and the energetic material properties and the charge parameters, developed a high level of integration Antistatic ability Small size of the integrated laser prototype Detonator. The laser detonator prototype antistatic ability of 25 kV. The research of this paper can solve the key design of laser detonator miniaturization and integration of weapons and equipment, satisfy the electromagnetic safety and micro weapons development of explosive demand.

  5. Integral Education for the Integral Child: A Qualitative Study of One Contemporary Experiment in Integral Elementary Education

    ERIC Educational Resources Information Center

    Barket, Ann-Terese

    2012-01-01

    A growing interest among educators, families, and students to personalize education and nurture the development of whole child has led to a new movement in elementary education: integral education. This qualitative study reported on the work of one school in that movement, the Integral Elementary School in La Jolla, California, to illuminate what…

  6. Authentic Integration: a model for integrating mathematics and science in the classroom

    NASA Astrophysics Data System (ADS)

    Treacy, Páraic; O'Donoghue, John

    2014-07-01

    Attempts at integrating mathematics and science have been made previously but no definitive, widely adopted teaching model has been developed to date. Research suggests that hands-on, practical, student-centred tasks should form a central element when designing an effective model for the integration of mathematics and science. Aided by this research, the author created a new model entitled 'Authentic Integration' which caters for the specific needs of integration of mathematics and science. This model requires that each lesson be based around a rich task which relates to the real world and ensures that hands-on group work, inquiry, and discussion are central to the lesson. It was found that Authentic Integration, when applied in four Irish post-primary schools, positively affected pupil understanding. The teachers who completed the intervention displayed a very positive attitude towards the approach, intimating that they would continue to implement the practice in their classrooms.

  7. Integrated Education. Feature Issue.

    ERIC Educational Resources Information Center

    York, Jennifer, Ed.; Vandercook, Terri, Ed.

    1988-01-01

    This "feature issue" provides various perspectives on a number of integrated education topics, including successful integration practices and strategies, the changing roles of teachers, the appropriate role of research, the history and future of integrated education, and the realization of dreams of life in the mainstream for children with severe…

  8. Fast integral methods for integrated optical systems simulations: a review

    NASA Astrophysics Data System (ADS)

    Kleemann, Bernd H.

    2015-09-01

    Boundary integral equation methods (BIM) or simply integral methods (IM) in the context of optical design and simulation are rigorous electromagnetic methods solving Helmholtz or Maxwell equations on the boundary (surface or interface of the structures between two materials) for scattering or/and diffraction purposes. This work is mainly restricted to integral methods for diffracting structures such as gratings, kinoforms, diffractive optical elements (DOEs), micro Fresnel lenses, computer generated holograms (CGHs), holographic or digital phase holograms, periodic lithographic structures, and the like. In most cases all of the mentioned structures have dimensions of thousands of wavelengths in diameter. Therefore, the basic methods necessary for the numerical treatment are locally applied electromagnetic grating diffraction algorithms. Interestingly, integral methods belong to the first electromagnetic methods investigated for grating diffraction. The development started in the mid 1960ies for gratings with infinite conductivity and it was mainly due to the good convergence of the integral methods especially for TM polarization. The first integral equation methods (IEM) for finite conductivity were the methods by D. Maystre at Fresnel Institute in Marseille: in 1972/74 for dielectric, and metallic gratings, and later for multiprofile, and other types of gratings and for photonic crystals. Other methods such as differential and modal methods suffered from unstable behaviour and slow convergence compared to BIMs for metallic gratings in TM polarization from the beginning to the mid 1990ies. The first BIM for gratings using a parametrization of the profile was developed at Karl-Weierstrass Institute in Berlin under a contract with Carl Zeiss Jena works in 1984-1986 by A. Pomp, J. Creutziger, and the author. Due to the parametrization, this method was able to deal with any kind of surface grating from the beginning: whether profiles with edges, overhanging non

  9. 2014 SRP Integration Transcript

    NASA Technical Reports Server (NTRS)

    Steinberg, Susan

    2014-01-01

    HRP's mission is to reduce the risks to human health and performance during long-duration spaceflight. The HRP Integrated Research Plan (IRP) contains the research plans for the 32 risks that require research to characterize and mitigate. From its inception the "integrate" aspect of the IRP has denoted the integrated nature of risks to human health and performance. Even though each risk in the IRP has its own research plan and is tracked separately, the interrelated nature of health and performance requires that they be addressed in an integrative or holistic fashion so that the connectedness of physiological systems within the human body and the integrated response to spaceflight can be addressed. Common characteristics of the spaceflight environment include altered gravity, atmospheres, and light/dark cycles; space radiation; isolation; noise; and periods of high or low workload. Long-term exposure to this unique environment produces a suite of physiological effects such as stress; vision, neurocognitive, and anthropometric changes; circadian misalignment; fluid shifts; cardiovascular deconditioning; immune dysregulation; and altered nutritional requirements. Expanding cross-disciplinary integrative approaches that synthesize concepts or data from two or more disciplines would improve the identification and characterization risk factors, and enable the development of countermeasures relevant to multiple risks. Cross-disciplinary approaches might also help to illuminate problem areas that may arise when a countermeasure adversely impacts risks other than those which it was developed to mitigate, or to identify groupings of physiological changes that are likely to occur that may impact the overall risk posture. In 2014 HRP embarked on a pilot study that combined four SRPs (and 12 HRP risks) - Behavioral Health, Sensorimotor, Cardiovascular, and Bone/Muscle - specifically to discuss cross-disciplinary integration. The points outlined below were suggested to seed the

  10. Relevance of Riverine Capability for Today’s Portuguese Navy

    DTIC Science & Technology

    2009-01-01

    Crespo, 537-550. 21 Cann, Brown Waters ofAfrica, 46. 22 Jose Alberto Lopes Carvalheira, "Acyao da Marinha em Aguas Interiores (1961-1971)" [Naval...Lopes Carvalheira, Jose Alberto. "Acyao da Marinha em Aguas Interiores (1961-1971)." [Naval Operations in Inland Waters (1961-1971)]. In the...Americas Country Antigua and Barbados Argentina Aruba Barbados Bermuda Bolivia Brazil Canada Chile Colombia Cuba Dominica Dominican Republic Equator Grenada

  11. An Archaeological Sample Survey of the Whitlow Ranch Reservoir, Pinal County, Arizona.

    DTIC Science & Technology

    1977-09-01

    in situ Hohokam developme,z. The Salado concept itself may be questioned; Hohokam and Salade cc-stitute similar manifes- tations and the criteria for...Gila Aqueducts, Agua Fria River to Gila River, Arizona. Arizona State University Anthropological Research Paper 1. Forrester, J. D. 1962 Folio of...Weaver, Donald E., Jr. 1974 Archaeological investigations at the Westwing site, AZ T:7:27 (ASU), Agua Fria River Valley, Arizona. Arizona State Univer

  12. Integrative dimensions of psychotherapy training.

    PubMed

    Greben, Daniel H

    2004-04-01

    This paper investigates the influence of integrative factors on psychotherapy education. The broad relevance of integrative psychotherapy to residency training and continuing mental health education is discussed. Following a review of the existing literature on the education of integrative psychotherapists, the article systematically examines the integrative and pedagogic issues to be considered in planning psychotherapy training informed by integrative principles. The integrative issues are organized into 5 categories: attitudinal set, knowledge base, clinical techniques and skills, developmental tasks and challenges, and systemic institutional factors. The educational issues can be divided into 4 categories: content, format and process, sequence, and faculty development. Brief descriptions of actual educational interventions illustrate the implementation of such ideas. Specific recommendations are made regarding the development of integrative educational initiatives and future study of unresolved questions.

  13. Context Oriented Information Integration

    NASA Astrophysics Data System (ADS)

    Mohania, Mukesh; Bhide, Manish; Roy, Prasan; Chakaravarthy, Venkatesan T.; Gupta, Himanshu

    Faced with growing knowledge management needs, enterprises are increasingly realizing the importance of seamlessly integrating critical business information distributed across both structured and unstructured data sources. Academicians have focused on this problem but there still remain a lot of obstacles for its widespread use in practice. One of the key problems is the absence of schema in unstructured text. In this paper we present a new paradigm for integrating information which overcomes this problem - that of Context Oriented Information Integration. The goal is to integrate unstructured data with the structured data present in the enterprise and use the extracted information to generate actionable insights for the enterprise. We present two techniques which enable context oriented information integration and show how they can be used for solving real world problems.

  14. Retroviral integration: Site matters

    PubMed Central

    Demeulemeester, Jonas; De Rijck, Jan

    2015-01-01

    Here, we review genomic target site selection during retroviral integration as a multistep process in which specific biases are introduced at each level. The first asymmetries are introduced when the virus takes a specific route into the nucleus. Next, by co‐opting distinct host cofactors, the integration machinery is guided to particular chromatin contexts. As the viral integrase captures a local target nucleosome, specific contacts introduce fine‐grained biases in the integration site distribution. In vivo, the established population of proviruses is subject to both positive and negative selection, thereby continuously reshaping the integration site distribution. By affecting stochastic proviral expression as well as the mutagenic potential of the virus, integration site choice may be an inherent part of the evolutionary strategies used by different retroviruses to maximise reproductive success. PMID:26293289

  15. Integrated environmental planning in the Philippines: A case study of the Palawan Integrated Environmental Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ganapin, D.J. Jr.

    1987-01-01

    Integrated environmental planning was analyzed using the case of the Palawan Integrated Environmental Program in the Philippines. The study explores the relationship between development and environmental planning and evaluates the importance of organizational coordination and timing in the integration of these two concerns. Factors affecting the accomplishment of the objectives of integrated environmental planning were also studied. Two planning phases of the Palawan Integrated Environmental Program were observed using the case study approach. Observations of various planning participants-consultants, middle level agency personnel, heads of local agencies-were also considered. The integration of environmental considerations in development planning was found to bemore » beneficial to both environmental and development concerns. The experience showed that such integration requiring tight organizational coordination and the proper timing of activities and outputs. The success of the Palawan Integrated Environmental Program was also found to depend on effective communication, the political functionality of the government, the leadership of its executives, the presence of appropriate structures of authority, sufficiency of funds and manpower and the availability of appropriate environmental planning techniques. Recommendations are provided to further strengthen the integration of environmental considerations in development planning and increase the effectiveness of integrated environmental programs.« less

  16. Integrated care: theory to practice.

    PubMed

    Stokes, Jonathan; Checkland, Kath; Kristensen, Søren Rud

    2016-10-01

    'Integrated care' is pitched as the solution to current health system challenges. In the literature, what integrated care actually involves is complex and contested. Multi-disciplinary team case management is frequently the primary focus of integrated care when implemented internationally. We examine the practical application of integrated care in the NHS in England to exemplify the prevalence of the case management focus. We look at the evidence for effectiveness of multi-disciplinary team case management, for the focus on high-risk groups and for integrated care more generally. We suggest realistic expectations of what integration of care alone can achieve and additional research questions. © The Author(s) 2016.

  17. Fostering Integrity in Research

    NASA Astrophysics Data System (ADS)

    McNutt, M. K.

    2017-12-01

    The responsible conduct of research requires that all involved in the research enterprise - researchers, sponsors, reviewers, publishers, and communicators - adhere to a set of integrity principles to protect the public's investment. Given the increasing complexity and globalization of the research enterprise, the National Academies recently re-examined and updated its integrity recommendations for researchers in the report Fostering Integrity in Research, with sponsorship from the National Science Foundation. Major departures from the previous recommendations 25-years earlier are the recognition that practices that were previously classified as merely questionable are indeed detrimental to the responsible conduct of research. Furthermore, the report concludes that there has been insufficient effort to respond to the threats that lapses in research integrity pose to the quality of research products and the reputation of researchers as deserving of the public trust. It recommends the creation of an independent, non-profit entity dedicated to promoting research integrity by serving as a resource and clearing house for expertise, advice, materials, and best practices on fostering research integrity and responding to allegations of research misconduct.

  18. Time-symmetric integration in astrophysics

    NASA Astrophysics Data System (ADS)

    Hernandez, David M.; Bertschinger, Edmund

    2018-04-01

    Calculating the long-term solution of ordinary differential equations, such as those of the N-body problem, is central to understanding a wide range of dynamics in astrophysics, from galaxy formation to planetary chaos. Because generally no analytic solution exists to these equations, researchers rely on numerical methods that are prone to various errors. In an effort to mitigate these errors, powerful symplectic integrators have been employed. But symplectic integrators can be severely limited because they are not compatible with adaptive stepping and thus they have difficulty in accommodating changing time and length scales. A promising alternative is time-reversible integration, which can handle adaptive time-stepping, but the errors due to time-reversible integration in astrophysics are less understood. The goal of this work is to study analytically and numerically the errors caused by time-reversible integration, with and without adaptive stepping. We derive the modified differential equations of these integrators to perform the error analysis. As an example, we consider the trapezoidal rule, a reversible non-symplectic integrator, and show that it gives secular energy error increase for a pendulum problem and for a Hénon-Heiles orbit. We conclude that using reversible integration does not guarantee good energy conservation and that, when possible, use of symplectic integrators is favoured. We also show that time-symmetry and time-reversibility are properties that are distinct for an integrator.

  19. Automatic detection, tracking and sensor integration

    NASA Astrophysics Data System (ADS)

    Trunk, G. V.

    1988-06-01

    This report surveys the state of the art of automatic detection, tracking, and sensor integration. In the area of detection, various noncoherent integrators such as the moving window integrator, feedback integrator, two-pole filter, binary integrator, and batch processor are discussed. Next, the three techniques for controlling false alarms, adapting thresholds, nonparametric detectors, and clutter maps are presented. In the area of tracking, a general outline is given of a track-while-scan system, and then a discussion is presented of the file system, contact-entry logic, coordinate systems, tracking filters, maneuver-following logic, tracking initiating, track-drop logic, and correlation procedures. Finally, in the area of multisensor integration the problems of colocated-radar integration, multisite-radar integration, radar-IFF integration, and radar-DF bearing strobe integration are treated.

  20. Enterprise Information System Integration Technology

    NASA Astrophysics Data System (ADS)

    Tanaka, Tetsuo; Yumoto, Masaki; Itsuki, Rei

    In the current rapidly changing business environment, companies need to be efficient and agile to survive and thrive. That is why flexible systems integration is urgent and crucial concern for any enterprise. For the meanwhile, systems integration technology is getting more complicated, and middleware types are beginning blur for decades. We sort system integration into four different types, “Delayed Federation", “Real-time Federation", “Delayed Integration", and “Real-time Integration". We also outline appropriate technology and architecture for each type.

  1. Acoustic integrated extinction.

    PubMed

    Norris, Andrew N

    2015-05-08

    The integrated extinction (IE) is defined as the integral of the scattering cross section as a function of wavelength. Sohl et al. (2007 J. Acoust. Soc. Am. 122 , 3206-3210. (doi:10.1121/1.2801546)) derived an IE expression for acoustic scattering that is causal, i.e. the scattered wavefront in the forward direction arrives later than the incident plane wave in the background medium. The IE formula was based on electromagnetic results, for which scattering is causal by default. Here, we derive a formula for the acoustic IE that is valid for causal and non-causal scattering. The general result is expressed as an integral of the time-dependent forward scattering function. The IE reduces to a finite integral for scatterers with zero long-wavelength monopole and dipole amplitudes. Implications for acoustic cloaking are discussed and a new metric is proposed for broadband acoustic transparency.

  2. A Generalized Technique in Numerical Integration

    NASA Astrophysics Data System (ADS)

    Safouhi, Hassan

    2018-02-01

    Integration by parts is one of the most popular techniques in the analysis of integrals and is one of the simplest methods to generate asymptotic expansions of integral representations. The product of the technique is usually a divergent series formed from evaluating boundary terms; however, sometimes the remaining integral is also evaluated. Due to the successive differentiation and anti-differentiation required to form the series or the remaining integral, the technique is difficult to apply to problems more complicated than the simplest. In this contribution, we explore a generalized and formalized integration by parts to create equivalent representations to some challenging integrals. As a demonstrative archetype, we examine Bessel integrals, Fresnel integrals and Airy functions.

  3. Integrated nursery pest management

    Treesearch

    R. Kasten Dumroese

    2012-01-01

    What is integrated pest management? Take a look at the definition of each word to better understand the concept. Two of the words (integrated and management) are relatively straightforward. Integrated means to blend pieces or concepts into a unified whole, and management is the wise use of techniques to successfully accomplish a desired outcome. A pest is any biotic (...

  4. Integral transforms of the quantum mechanical path integral: Hit function and path-averaged potential.

    PubMed

    Edwards, James P; Gerber, Urs; Schubert, Christian; Trejo, Maria Anabel; Weber, Axel

    2018-04-01

    We introduce two integral transforms of the quantum mechanical transition kernel that represent physical information about the path integral. These transforms can be interpreted as probability distributions on particle trajectories measuring respectively the relative contribution to the path integral from paths crossing a given spatial point (the hit function) and the likelihood of values of the line integral of the potential along a path in the ensemble (the path-averaged potential).

  5. Integral transforms of the quantum mechanical path integral: Hit function and path-averaged potential

    NASA Astrophysics Data System (ADS)

    Edwards, James P.; Gerber, Urs; Schubert, Christian; Trejo, Maria Anabel; Weber, Axel

    2018-04-01

    We introduce two integral transforms of the quantum mechanical transition kernel that represent physical information about the path integral. These transforms can be interpreted as probability distributions on particle trajectories measuring respectively the relative contribution to the path integral from paths crossing a given spatial point (the hit function) and the likelihood of values of the line integral of the potential along a path in the ensemble (the path-averaged potential).

  6. A Review of "Integrity[TM]"

    ERIC Educational Resources Information Center

    Veldkamp, Bernard P.

    2008-01-01

    Integrity[TM], an online application for testing both the statistical integrity of the test and the academic integrity of the examinees, was evaluated for this review. Program features and the program output are described. An overview of the statistics in Integrity[TM] is provided, and the application is illustrated with a small simulation study.…

  7. Late Miocene ignimbrites at the southern Puna-northern Sierras Pampeanas border (˜27°S): Stratigraphic correlation

    NASA Astrophysics Data System (ADS)

    Montero-López, Carolina; Guzmán, Silvina; Barrios, Fabiola

    2015-10-01

    New field observations and petrographic and geochemical data of pyroclastic deposits exposed along the Las Papas valley (border between southern Puna and northern Sierras Pampeanas, Argentina) and further north, lead us to propose a new stratigraphic correlation and classification of the late Miocene volcanism in this area. We redefine the Las Papas, Las Juntas, Aguada Alumbrera and Rosada ignimbrites and define the Agua Caliente and Del Medio ignimbrites. The whole set of ignimbrites are rhyolites and less frequently dacites of calc-alkaline affinity. In the present contribution we divide ignimbrites into the Agua Negra and Rincón groups, based mainly on their geochemical signature. The Agua Negra Group is formed by the Las Papas and Las Juntas ignimbrites, indurated and welded, lithic-rich, with crystal-poor pumices and crystal-rich matrix. The Rincón Group comprises the Agua Caliente, Aguada Alumbrera, Rosada and Del Medio ignimbrites, with variable welding degrees, lithic and crystal content. The greater enrichment of crystals in the matrix in comparison with the crystal content in pumices indicates significant elutriation during flow transport and thus volume estimations are to be considered lower bounds for the actual erupted volume. The total minimum estimated volume for the ignimbrites of the Agua Negra and Rincón groups is 2.8 km3 (2.3 km3 DRE). Field relationships and new analytical data indicate that the different acid ignimbrites that crop out in this small area are related to at least two different magma chambers. The widespread Quaternary volcanism in this area covers the older deposits, thus making it difficult to recognize the volcanic centers that produced these late Miocene ignimbrites.

  8. Algebraic integrability: a survey.

    PubMed

    Vanhaecke, Pol

    2008-03-28

    We give a concise introduction to the notion of algebraic integrability. Our exposition is based on examples and phenomena, rather than on detailed proofs of abstract theorems. We mainly focus on algebraic integrability in the sense of Adler-van Moerbeke, where the fibres of the momentum map are affine parts of Abelian varieties; as it turns out, most examples from classical mechanics are of this form. Two criteria are given for such systems (Kowalevski-Painlevé and Lyapunov) and each is illustrated in one example. We show in the case of a relatively simple example how one proves algebraic integrability, starting from the differential equations for the integrable vector field. For Hamiltonian systems that are algebraically integrable in the generalized sense, two examples are given, which illustrate the non-compact analogues of Abelian varieties which typically appear in such systems.

  9. Implicit integration in a case of integrative visual agnosia.

    PubMed

    Aviezer, Hillel; Landau, Ayelet N; Robertson, Lynn C; Peterson, Mary A; Soroker, Nachum; Sacher, Yaron; Bonneh, Yoram; Bentin, Shlomo

    2007-05-15

    We present a case (SE) with integrative visual agnosia following ischemic stroke affecting the right dorsal and the left ventral pathways of the visual system. Despite his inability to identify global hierarchical letters [Navon, D. (1977). Forest before trees: The precedence of global features in visual perception. Cognitive Psychology, 9, 353-383], and his dense object agnosia, SE showed normal global-to-local interference when responding to local letters in Navon hierarchical stimuli and significant picture-word identity priming in a semantic decision task for words. Since priming was absent if these features were scrambled, it stands to reason that these effects were not due to priming by distinctive features. The contrast between priming effects induced by coherent and scrambled stimuli is consistent with implicit but not explicit integration of features into a unified whole. We went on to show that possible/impossible object decisions were facilitated by words in a word-picture priming task, suggesting that prompts could activate perceptually integrated images in a backward fashion. We conclude that the absence of SE's ability to identify visual objects except through tedious serial construction reflects a deficit in accessing an integrated visual representation through bottom-up visual processing alone. However, top-down generated images can help activate these visual representations through semantic links.

  10. Costs of Physician-Hospital Integration

    PubMed Central

    Cho, Na-Eun

    2015-01-01

    Abstract Given that the enactment of the Patient Protection and Affordable Care Act of 2010 is expected to generate forces toward physician-hospital integration, this study examined an understudied, albeit important, area of costs incurred in physician-hospital integration. Such costs were analyzed through 24 semi-structured interviews with physicians and hospital administrators in a multiple-case, inductive study. Two extreme types of physician-hospital arrangements were examined: an employed model (ie, integrated salary model, a group of physicians integrated by a hospital system) and a private practice (ie, a physician or group of physicians who are independent of economic or policy control). Interviews noted that integration leads to 3 evident costs, namely, monitoring, coordination, and cooperation costs. Improving our understanding of the kinds of costs that are incurred after physician-hospital integration will help hospitals and physicians to avoid common failures after integration. PMID:26496300

  11. Integrated Marketing Communications

    ERIC Educational Resources Information Center

    Black, Jim

    2004-01-01

    Integration has become a cliche in enrollment management and student services circles. The term is used to describe everything from integrated marketing to seamless services. Often, it defines organizational structures, processes, student information systems, and even communities. In Robert Sevier's article in this issue of "College and…

  12. Ready, Set, Integrate!

    ERIC Educational Resources Information Center

    McCombs, John

    2003-01-01

    Describes how the American Embassy School (AES) in New Delhi, India achieved school-wide technology integration. Discusses development of a new network; beginning to mentor; organizing the Technology Integration Plan (TIP) by software application; implementing the plan; assessing progress; and results, which overall, were positive. (AEF)

  13. Integrated Modeling Environment

    NASA Technical Reports Server (NTRS)

    Mosier, Gary; Stone, Paul; Holtery, Christopher

    2006-01-01

    The Integrated Modeling Environment (IME) is a software system that establishes a centralized Web-based interface for integrating people (who may be geographically dispersed), processes, and data involved in a common engineering project. The IME includes software tools for life-cycle management, configuration management, visualization, and collaboration.

  14. Integrated smart structures wingbox

    NASA Astrophysics Data System (ADS)

    Simon, Solomon H.

    1993-09-01

    One objective of smart structures development is to demonstrate the ability of a mechanical component to monitor its own structural integrity and health. Achievement of this objective requires the integration of different technologies, i.e.: (1) structures, (2) sensors, and (3) artificial intelligence. We coordinated a team of experts from these three fields. These experts used reliable knowledge towards the forefront of their technologies and combined the appropriate features into an integrated hardware/software smart structures wingbox (SSW) test article. A 1/4 in. hole was drilled into the SSW test article. Although the smart structure had never seen damage of this type, it correctly recognized and located the damage. Based on a knowledge-based simulation, quantification and assessment were also carried out. We have demonstrated that the SSW integrated hardware & software test article can perform six related functions: (1) identification of a defect; (2) location of the defect; (3) quantification of the amount of damage; (4) assessment of performance degradation; (5) continued monitoring in spite of damage; and (6) continuous recording of integrity data. We present the successful results of the integrated test article in this paper, along with plans for future development and deployment of the technology.

  15. Integrated control-structure design

    NASA Technical Reports Server (NTRS)

    Hunziker, K. Scott; Kraft, Raymond H.; Bossi, Joseph A.

    1991-01-01

    A new approach for the design and control of flexible space structures is described. The approach integrates the structure and controller design processes thereby providing extra opportunities for avoiding some of the disastrous effects of control-structures interaction and for discovering new, unexpected avenues of future structural design. A control formulation based on Boyd's implementation of Youla parameterization is employed. Control design parameters are coupled with structural design variables to produce a set of integrated-design variables which are selected through optimization-based methodology. A performance index reflecting spacecraft mission goals and constraints is formulated and optimized with respect to the integrated design variables. Initial studies have been concerned with achieving mission requirements with a lighter, more flexible space structure. Details of the formulation of the integrated-design approach are presented and results are given from a study involving the integrated redesign of a flexible geostationary platform.

  16. The implementation of integrated care: the empirical validation of the Development Model for Integrated care.

    PubMed

    Minkman, Mirella M N; Vermeulen, Robbert P; Ahaus, Kees T B; Huijsman, Robbert

    2011-07-30

    Integrated care is considered as a strategy to improve the delivery, efficiency, client outcomes and satisfaction rates of health care. To integrate the care from multiple providers into a coherent client-focused service, a large number of activities and agreements have to be implemented like streamlining information flows and patient transfers. The Development Model for Integrated care (DMIC) describes nine clusters containing in total 89 elements that contribute to the integration of care. We have empirically validated this model in practice by assessing the relevance, implementation and plans of the elements in three integrated care service settings in The Netherlands: stroke, acute myocardial infarct (AMI), and dementia. Based on the DMIC, a survey was developed for integrated care coordinators. We invited all Dutch stroke and AMI-services, as well as the dementia care networks to participate, of which 84 did (response rate 83%). Data were collected on relevance, presence, and year of implementation of the 89 elements. The data analysis was done by means of descriptive statistics, Chi Square, ANOVA and Kruskal-Wallis H tests. The results indicate that the integrated care practice organizations in all three care settings rated the nine clusters and 89 elements of the DMIC as highly relevant. The average number of elements implemented was 50 ± 18, 42 ± 13, and 45 ± 22 for stroke, acute myocardial infarction, and dementia care services, respectively. Although the dementia networks were significantly younger, their numbers of implemented elements were comparable to those of the other services. The analyses of the implementation timelines showed that the older integrated care services had fewer plans for further implementation than the younger ones. Integrated care coordinators stated that the DMIC helped them to assess their integrated care development in practice and supported them in obtaining ideas for expanding their integrated care activities. Although the

  17. Avionics systems integration technology

    NASA Technical Reports Server (NTRS)

    Stech, George; Williams, James R.

    1988-01-01

    A very dramatic and continuing explosion in digital electronics technology has been taking place in the last decade. The prudent and timely application of this technology will provide Army aviation the capability to prevail against a numerically superior enemy threat. The Army and NASA have exploited this technology explosion in the development and application of avionics systems integration technology for new and future aviation systems. A few selected Army avionics integration technology base efforts are discussed. Also discussed is the Avionics Integration Research Laboratory (AIRLAB) that NASA has established at Langley for research into the integration and validation of avionics systems, and evaluation of advanced technology in a total systems context.

  18. Area Assessment. Costa Rica

    DTIC Science & Technology

    1984-01-01

    8217 ’ 20 3 G. Los Chiles ■’, Los Chiles 20 .:.’ 𔃽 ■■ ’■ ST ■ .- r. ■-■■’ ’ ■ .. ;-^’ ^" ■: C LI I JIGS...Ciudad Quesada, Pital, La Fortiona de San Carlos, Aguas Zsircas, Altanura, Venecia, Sabanilia, Carrizal, La S’oiza, Orotina, La...Refonna, San Rafael de Ojo de Agua , San Miateo, Sajita Rosa de Curtris, Guatuso. ■ , V. Region Pacifico Seco

  19. Impacts of Climate Change on Colombia’s National and Regional Security

    DTIC Science & Technology

    2009-10-01

    Peru, and Chile have relatively diverse, industrialized economies and greater domestic resources and state capaci- ties for adaptation. Bolivia...Change on Colombia’s National and Regional Security References 1 Colombia, Sistema de Informacion sobre el Uso del Agua en la Agricultura y el Medio...Jul 2009. "El cambio climatico en Colombia." Unpublished report shared with authors. IDEAM. 26 "El agua para 40 millones de personas esta en riesgo

  20. Area Handbook Series Guatemala, A Country Study,

    DTIC Science & Technology

    1983-05-01

    o’independencee, the cp tanc general of’ Guatemsala consisted of the present-day republics of’ C;entral Amierica-Guatemnala, El Salvador, (Ionduras, Nicar- agua ...countries that maintained significant political relationships with Guatemala were Chile and Argentina. Both had active military relationships with...1 d somiething tobreak (downi time, coliiitr\\s grossl\\yneItial 204 lburisf maZUrke’t San Anitoni o .Aguasv Cali’n tc. Resvidenats in San Antonio Aguas

  1. The Coast Artillery Journal. Volume 74, Number 6, September-October 1931

    DTIC Science & Technology

    1931-10-01

    Towns with the Primary Mission of Denying Such Towns to the Bandits This form of occupation became necessary in Nicar- agua in the summer and fall of 1927...such never materialized. Surprise Attacks on Bandit Camps Our first successful attack of this nature in Nicar- agua occurred in the first part of...complete reorganization of her military forces. Com- pulsory training is abolished. How difficult her situ - ation has become may be realized from the

  2. Review of Statistical Learning Methods in Integrated Omics Studies (An Integrated Information Science).

    PubMed

    Zeng, Irene Sui Lan; Lumley, Thomas

    2018-01-01

    Integrated omics is becoming a new channel for investigating the complex molecular system in modern biological science and sets a foundation for systematic learning for precision medicine. The statistical/machine learning methods that have emerged in the past decade for integrated omics are not only innovative but also multidisciplinary with integrated knowledge in biology, medicine, statistics, machine learning, and artificial intelligence. Here, we review the nontrivial classes of learning methods from the statistical aspects and streamline these learning methods within the statistical learning framework. The intriguing findings from the review are that the methods used are generalizable to other disciplines with complex systematic structure, and the integrated omics is part of an integrated information science which has collated and integrated different types of information for inferences and decision making. We review the statistical learning methods of exploratory and supervised learning from 42 publications. We also discuss the strengths and limitations of the extended principal component analysis, cluster analysis, network analysis, and regression methods. Statistical techniques such as penalization for sparsity induction when there are fewer observations than the number of features and using Bayesian approach when there are prior knowledge to be integrated are also included in the commentary. For the completeness of the review, a table of currently available software and packages from 23 publications for omics are summarized in the appendix.

  3. Community integration after burn injuries.

    PubMed

    Esselman, P C; Ptacek, J T; Kowalske, K; Cromes, G F; deLateur, B J; Engrav, L H

    2001-01-01

    Evaluation of community integration is a meaningful outcome criterion after major burn injury. The Community Integration Questionnaire (CIQ) was administered to 463 individuals with major burn injuries. The CIQ results in Total, Home Integration, Social Integration, and Productivity scores. The purposes of this study were to determine change in CIQ scores over time and what burn injury and demographic factors predict CIQ scores. The CIQ scores did not change significantly from 6 to 12 to 24 months postburn injury. Home integration scores were best predicted by sex and living situation; Social Integration scores by marital status; and Productivity scores by functional outcome, burn severity, age, and preburn work factors. The data demonstrate that individuals with burn injuries have significant difficulties with community integration due to burn and nonburn related factors. CIQ scores did not improve over time but improvement may have occurred before the initial 6-month postburn injury follow-up in this study.

  4. Integrated health systems.

    PubMed

    Shortell, Stephen M; McCurdy, Rodney K

    2010-01-01

    Before meaningful gains in improving the value of health care in the US can be achieved, the fragmented nature in which health care is financed and delivered must be addressed. One type of healthcare organization, the Integrated Delivery System (IDS), is poised to play a pivotal role in reform efforts. What are these systems? What is the current evidence regarding their performance? What are the current barriers to their establishment and how can these barriers be removed? This chapter addresses these important questions. Although there are many types of IDS' in the US healthcare landscape, the chapter begins by identifying the necessary healthcare components that encompass an IDS and discusses the levels of integration that are important to improving health care quality and value. Next, it explores the recent evidence regarding IDS performance which, while generally positive, is less than what it could be if there were greater focus on clinical integration. To highlight, the chapter discusses the efficacy of system engineering initiatives in two examples of large, fully integrated systems: Kaiser-Permanente and the Veterans Health Administration. The evidence here is strong that the impact of system engineering methods is enhanced through the integration of processes, goals and outcomes. Reforms necessary to encourage the development of IDS' include: 1) the development of payment mechanisms designed to increase greater inter-dependency of hospitals and physicians; 2) the modification or removal of several regulatory barriers to greater clinical integration; and 3) the establishment of a more robust data collection and reporting system to increase transparency and accountability. The chapter concludes with a framework for considering these reforms across strategic, structural, cultural, and technical dimensions.

  5. Completely integrable 2D Lagrangian systems and related integrable geodesic flows on various manifolds

    NASA Astrophysics Data System (ADS)

    Yehia, Hamad M.

    2013-08-01

    In this study we have formulated a theorem that generates deformations of the natural integrable conservative systems in the plane into integrable systems on Riemannian and other manifolds by introducing additional parameters into their structures. The relation of explicit solutions of the new and the original dynamics to the corresponding Jacobi (Maupertuis) geodesic flow is clarified. For illustration, we apply the result to three concrete examples of the many available integrable systems in the literature. Complementary integrals in those systems are polynomial in velocity with degrees 3, 4 and 6, respectively. As a special case of the first deformed system, a new several-parameter family of integrable mechanical systems (and geodesic flows) on S2 is constructed.

  6. The Integrative Self: How Self-Reference Integrates Perception and Memory.

    PubMed

    Sui, Jie; Humphreys, Glyn W

    2015-12-01

    We propose a new account of how self-reference affects information processing. We report evidence that self-reference affects the binding of memory to source, the integration of parts into perceptual wholes, and the ability to switch from a prior association to new associations. Self-reference also influences the integration of different stages of processing, linking attention to decision making, and affects the coupling between brain regions mediating self-representation and attention to the environment. Taken together, the data suggest that self-reference acts as a form of 'integrative glue' which can either enhance or disrupt performance, depending on the task context. We discuss the implications for understanding the self, and future directions for research. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Integration of a mobile-integrated therapy with electronic health records: lessons learned.

    PubMed

    Peeples, Malinda M; Iyer, Anand K; Cohen, Joshua L

    2013-05-01

    Responses to the chronic disease epidemic have predominantly been standardized in their approach to date. Barriers to better health outcomes remain, and effective management requires patient-specific data and disease state knowledge be presented in methods that foster clinical decision-making and patient self-management. Mobile technology provides a new platform for data collection and patient-provider communication. The mobile device represents a personalized platform that is available to the patient on a 24/7 basis. Mobile-integrated therapy (MIT) is the convergence of mobile technology, clinical and behavioral science, and scientifically validated clinical outcomes. In this article, we highlight the lessons learned from functional integration of a Food and Drug Administration-cleared type 2 diabetes MIT into the electronic health record (EHR) of a multiphysician practice within a large, urban, academic medical center. In-depth interviews were conducted with integration stakeholder groups: mobile and EHR software and information technology teams, clinical end users, project managers, and business analysts. Interviews were summarized and categorized into lessons learned using the Architecture for Integrated Mobility® framework. Findings from the diverse stakeholder group of a MIT-EHR integration project indicate that user workflow, software system persistence, environment configuration, device connectivity and security, organizational processes, and data exchange heuristics are key issues that must be addressed. Mobile-integrated therapy that integrates patient self-management data with medical record data provides the opportunity to understand the potential benefits of bidirectional data sharing and reporting that are most valuable in advancing better health and better care in a cost-effective way that is scalable for all chronic diseases. © 2013 Diabetes Technology Society.

  8. Integrating Community Resources.

    ERIC Educational Resources Information Center

    Courtney, Linda J., Ed.

    This manual is designed to provide resource managers, advocates, and social service personnel with information about the integration of community services for persons with traumatic brain injury (TBI). The materials encompass the values of independence, productivity, and integration in the delivery of resources and services to persons with TBI.…

  9. Vertical and lateral heterogeneous integration

    NASA Astrophysics Data System (ADS)

    Geske, Jon; Okuno, Yae L.; Bowers, John E.; Jayaraman, Vijay

    2001-09-01

    A technique for achieving large-scale monolithic integration of lattice-mismatched materials in the vertical direction and the lateral integration of dissimilar lattice-matched structures has been developed. The technique uses a single nonplanar direct-wafer-bond step to transform vertically integrated epitaxial structures into lateral epitaxial variation across the surface of a wafer. Nonplanar wafer bonding is demonstrated by integrating four different unstrained multi-quantum-well active regions lattice matched to InP on a GaAs wafer surface. Microscopy is used to verify the quality of the bonded interface, and photoluminescence is used to verify that the bonding process does not degrade the optical quality of the laterally integrated wells. The authors propose this technique as a means to achieve greater levels of wafer-scale integration in optical, electrical, and micromechanical devices.

  10. Topological Properties of Some Integrated Circuits for Very Large Scale Integration Chip Designs

    NASA Astrophysics Data System (ADS)

    Swanson, S.; Lanzerotti, M.; Vernizzi, G.; Kujawski, J.; Weatherwax, A.

    2015-03-01

    This talk presents topological properties of integrated circuits for Very Large Scale Integration chip designs. These circuits can be implemented in very large scale integrated circuits, such as those in high performance microprocessors. Prior work considered basic combinational logic functions and produced a mathematical framework based on algebraic topology for integrated circuits composed of logic gates. Prior work also produced an historically-equivalent interpretation of Mr. E. F. Rent's work for today's complex circuitry in modern high performance microprocessors, where a heuristic linear relationship was observed between the number of connections and number of logic gates. This talk will examine topological properties and connectivity of more complex functionally-equivalent integrated circuits. The views expressed in this article are those of the author and do not reflect the official policy or position of the United States Air Force, Department of Defense or the U.S. Government.

  11. Mediator infrastructure for information integration and semantic data integration environment for biomedical research.

    PubMed

    Grethe, Jeffrey S; Ross, Edward; Little, David; Sanders, Brian; Gupta, Amarnath; Astakhov, Vadim

    2009-01-01

    This paper presents current progress in the development of semantic data integration environment which is a part of the Biomedical Informatics Research Network (BIRN; http://www.nbirn.net) project. BIRN is sponsored by the National Center for Research Resources (NCRR), a component of the National Institutes of Health (NIH). A goal is the development of a cyberinfrastructure for biomedical research that supports advance data acquisition, data storage, data management, data integration, data mining, data visualization, and other computing and information processing services over the Internet. Each participating institution maintains storage of their experimental or computationally derived data. Mediator-based data integration system performs semantic integration over the databases to enable researchers to perform analyses based on larger and broader datasets than would be available from any single institution's data. This paper describes recent revision of the system architecture, implementation, and capabilities of the semantically based data integration environment for BIRN.

  12. Integrated Sensitivity Analysis Workflow

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Friedman-Hill, Ernest J.; Hoffman, Edward L.; Gibson, Marcus J.

    2014-08-01

    Sensitivity analysis is a crucial element of rigorous engineering analysis, but performing such an analysis on a complex model is difficult and time consuming. The mission of the DART Workbench team at Sandia National Laboratories is to lower the barriers to adoption of advanced analysis tools through software integration. The integrated environment guides the engineer in the use of these integrated tools and greatly reduces the cycle time for engineering analysis.

  13. The observation of biology implemented by integrated religion values in integrated Islamic school (Decriptive Study in X Integrated Senior Hight School Tasikmalaya)

    NASA Astrophysics Data System (ADS)

    Nurjanah, E.; Adisendjaja, Y. H.; Kusumastuti, M. N.

    2018-05-01

    The learning Integrated Religious value is one of the efforts to increase the motivation of learning and building the student character. This study aims to describe the application of Biology learning integrated religion values in Integrated Islamic School. Research methods used in this research is descriptive. Participants in this study involved the headmaster, headmaster of curriculum, biology teachers, boarding school teachers, the lead of boarding schools, and students. The instruments used are interview, observation and the student questionnaire about learning biology. The results showed that learning in X school consists of two curriculums, there was the curriculum of national education and curriculum of boarding school. The curriculum of national education referred to 2013 curriculum and boarding school curriculum referred to the curriculum of Salafi boarding school (Kitab Kuning). However, in its learning process not delivered integrated. The main obstacle to implementing the learning integrated religious values are 1) the background of general teacher education did not know of any connection between biology subject and subject that are studied in boarding school; 2) schools did not form the teaching team; 3) unavailability of materials integrated religious values.

  14. Integrity-Based Budgeting

    ERIC Educational Resources Information Center

    Kaleba, Frank

    2008-01-01

    The central problem for the facility manager of large portfolios is not the accuracy of data, but rather data integrity. Data integrity means that it's (1) acceptable to the users; (2) based upon an objective source; (3) reproducible; and (4) internally consistent. Manns and Katsinas, in their January/February 2006 Facilities Manager article…

  15. A Policy Guide on Integrated Care (PGIC): Lessons Learned from EU Project INTEGRATE and Beyond

    PubMed Central

    Devroey, Dirk

    2017-01-01

    Efforts are underway in many European countries to channel efforts into creating improved integrated health and social care services. But most countries lack a strategic plan that is sustainable over time, and that reflects a comprehensive systems perspective. The Policy Guide on Integrated Care (PGIC) as presented in this paper resulted from experiences with the EU Project INTEGRATE and our own work with healthcare reform for patients with chronic conditions at the national and international level. This project is one of the largest EU funded projects on Integrated Care, conducted over a four-year period (2012–2016) and included partners from nine European countries. Project Integrate aimed to gain insights into the leadership, management and delivery of integrated care to support European care systems to respond to the challenges of ageing populations and the rise of people living with long-term conditions. The objective of this paper is to describe the PGIC as both a tool and a reasoning flow that aims at supporting policy makers at the national and international level with the development and implementation of integrated care. Any Policy Guide on Integrated should build upon three building blocks, being a mission, vision and a strategy that aim at capturing the large amount of factors that directly or indirectly influence the successful development of integrated care. PMID:29588631

  16. A Policy Guide on Integrated Care (PGIC): Lessons Learned from EU Project INTEGRATE and Beyond.

    PubMed

    Borgermans, Liesbeth; Devroey, Dirk

    2017-09-25

    Efforts are underway in many European countries to channel efforts into creating improved integrated health and social care services. But most countries lack a strategic plan that is sustainable over time, and that reflects a comprehensive systems perspective. The Policy Guide on Integrated Care (PGIC) as presented in this paper resulted from experiences with the EU Project INTEGRATE and our own work with healthcare reform for patients with chronic conditions at the national and international level. This project is one of the largest EU funded projects on Integrated Care, conducted over a four-year period (2012-2016) and included partners from nine European countries. Project Integrate aimed to gain insights into the leadership, management and delivery of integrated care to support European care systems to respond to the challenges of ageing populations and the rise of people living with long-term conditions. The objective of this paper is to describe the PGIC as both a tool and a reasoning flow that aims at supporting policy makers at the national and international level with the development and implementation of integrated care. Any Policy Guide on Integrated should build upon three building blocks, being a mission, vision and a strategy that aim at capturing the large amount of factors that directly or indirectly influence the successful development of integrated care.

  17. Perspective: deconstructing integration: a framework for the rational application of integration as a guiding curricular strategy.

    PubMed

    Goldman, Ellen; Schroth, W Scott

    2012-06-01

    In response to historical criticism, evolving accreditation standards, and recent reports on curricula, medical educators and medical schools have been eagerly pursuing integration as a goal of curricular reform. The general education literature broadly considers integration to be the deliberate unification of separate areas of knowledge, and it provides support for the concept that integration better meets the needs of adult learners in professional education. The use of integration as a curricular goal is not without its critics, however, nor is it free of difficulties in implementation. In this perspective, the authors propose that most of these difficulties arise from a failure to recognize that integration is a strategy for curricular development rather than a goal in itself, and they argue that adopting a systematic approach to integration offers many potential benefits. They articulate the conceptual and practical issues that they believe are critical to consider in order to achieve successful curricular integration, and they suggest that integration should be approached as a subset of broader curriculum development decisions. They propose a three-level framework for applying integration as a guiding curricular strategy, in which decisions about integration must follow curricular decisions made at the program level, the course level, and then the individual session level.

  18. Critical Perspectives of Pedagogical Approaches to Reversing the Order of Integration in Double Integrals

    ERIC Educational Resources Information Center

    Tisdell, Christopher C.

    2017-01-01

    This paper presents some critical perspectives regarding pedagogical approaches to the method of reversing the order of integration in double integrals from prevailing educational literature on multivariable calculus. First, we question the message found in popular textbooks that the traditional process of reversing the order of integration is…

  19. Innovation in Evaluating the Impact of Integrated Service-Delivery: The Integra Indexes of HIV and Reproductive Health Integration.

    PubMed

    Mayhew, Susannah H; Ploubidis, George B; Sloggett, Andy; Church, Kathryn; Obure, Carol D; Birdthistle, Isolde; Sweeney, Sedona; Warren, Charlotte E; Watts, Charlotte; Vassall, Anna

    2016-01-01

    The body of knowledge on evaluating complex interventions for integrated healthcare lacks both common definitions of 'integrated service delivery' and standard measures of impact. Using multiple data sources in combination with statistical modelling the aim of this study is to develop a measure of HIV-reproductive health (HIV-RH) service integration that can be used to assess the degree of service integration, and the degree to which integration may have health benefits to clients, or reduce service costs. Data were drawn from the Integra Initiative's client flow (8,263 clients in Swaziland and 25,539 in Kenya) and costing tools implemented between 2008-2012 in 40 clinics providing RH services in Kenya and Swaziland. We used latent variable measurement models to derive dimensions of HIV-RH integration using these data, which quantified the extent and type of integration between HIV and RH services in Kenya and Swaziland. The modelling produced two clear and uncorrelated dimensions of integration at facility level leading to the development of two sub-indexes: a Structural Integration Index (integrated physical and human resource infrastructure) and a Functional Integration Index (integrated delivery of services to clients). The findings highlight the importance of multi-dimensional assessments of integration, suggesting that structural integration is not sufficient to achieve the integrated delivery of care to clients--i.e. "functional integration". These Indexes are an important methodological contribution for evaluating complex multi-service interventions. They help address the need to broaden traditional evaluations of integrated HIV-RH care through the incorporation of a functional integration measure, to avoid misleading conclusions on its 'impact' on health outcomes. This is particularly important for decision-makers seeking to promote integration in resource constrained environments.

  20. Geochemistry of thermal fluids in NW Honduras: New perspectives for exploitation of geothermal areas in the southern Sula graben

    NASA Astrophysics Data System (ADS)

    Capaccioni, Bruno; Franco, Tassi; Alberto, Renzulli; Orlando, Vaselli; Marco, Menichetti; Salvatore, Inguaggiato

    2014-06-01

    The results of a geochemical survey on thermal waters and, for the first time for this site, gas discharges in five geothermal sites (Azacualpa "La Cueva", Río Ulua, Río Gualcarque, El Olivar and Laguna de Agua Caliente) in NW Honduras are here presented and discussed. El Olivar and Laguna de Agua Caliente, in the southern part of the Sula graben are very close to a Quaternary basaltic field, whereas Azacualpa "La Cueva", Río Ulua and Río Gualcarque, located to the southwest of the Yojoa Lake, direcly emerge from the Cretaceous limestone deposits. The measured temperatures range between 37.5 and 104.8 °C. "Mature", alkaline, Na-SO4 thermal waters discharge from Azacualpa "La Cueva", while those from El Olivar and Laguna de Agua Caliente are "immature" and show a Na-HCO3 composition. Chemical equilibria of waters and gases from the Azacualpa "La Cueva" thermal springs indicate temperatures ranging from 150 to 200 °C. Conversely, gas discharges from El Olivar and Laguna de Agua Caliente have attained a partial chemical equilibrium in the liquid phase at slightly higher temperatures (200-250 °C), although gas-gas faster reactions involving CO seem to be adjusted in an isothermally separated vapor phase. Unlike Azacualpa, SiO2 geothermometer at El Olivar and Laguna de Agua Caliente indicates equilibrium temperatures for the liquid phase much lower than those calculated for the gas phase (≤ 120 °C). We conclude that thermal waters from the Azacualpa area likely represent the direct emergence of a water dominated reservoir having temperatures ≤ 150-200 °C. By contrast, at El Olivar and Laguna de Agua Caliente hot springs are supplied by a boiling shallow aquifer fed by a vapor phase rising from a steam-dominated zone. The above geochemical model is consistent with a geothermal reservoir hosted within the Cretaceous carbonate sequences of the Yojoa Group in the whole investigated sites. The reservoir extensively crops out in the Azacualpa area whereas the

  1. Induction as Knowledge Integration

    NASA Technical Reports Server (NTRS)

    Smith, Benjamin D.; Rosenbloom, Paul S.

    1996-01-01

    Two key issues for induction algorithms are the accuracy of the learned hypothesis and the computational resources consumed in inducing that hypothesis. One of the most promising ways to improve performance along both dimensions is to make use of additional knowledge. Multi-strategy learning algorithms tackle this problem by employing several strategies for handling different kinds of knowledge in different ways. However, integrating knowledge into an induction algorithm can be difficult when the new knowledge differs significantly from the knowledge the algorithm already uses. In many cases the algorithm must be rewritten. This paper presents Knowledge Integration framework for Induction (KII), a KII, that provides a uniform mechanism for integrating knowledge into induction. In theory, arbitrary knowledge can be integrated with this mechanism, but in practice the knowledge representation language determines both the knowledge that can be integrated, and the costs of integration and induction. By instantiating KII with various set representations, algorithms can be generated at different trade-off points along these dimensions. One instantiation of KII, called RS-KII, is presented that can implement hybrid induction algorithms, depending on which knowledge it utilizes. RS-KII is demonstrated to implement AQ-11, as well as a hybrid algorithm that utilizes a domain theory and noisy examples. Other algorithms are also possible.

  2. The power of product integrity.

    PubMed

    Clark, K B; Fujimoto, T

    1990-01-01

    In the dictionary, integrity means wholeness, completeness, soundness. In products, integrity is the source of sustainable competitive advantage. Products with integrity perform superbly, provide good value, and satisfy customers' expectations in every respect, including such intangibles as their look and feel. Consider this example from the auto industry. In 1987, Mazda put a racy four-wheel steering system in a five-door family hatchback. Honda introduced a comparable system in the Prelude, a sporty, two-door coupe. Most of Honda's customers installed the new technology; Mazda's system sold poorly. Potential customers felt the fit--or misfit--between the car and the new component, and they responded accordingly. Companies that consistently develop products with integrity are coherent, integrated organizations. This internal integrity is visible at the level of strategy and structure, in management and organization, and in the skills, attitudes, and behavior of individual designers, engineers, and operators. Moreover, these companies are integrated externally: customers become part of the development organization. Integrity starts with a product concept that describes the new product from the potential customer's perspective--"pocket rocket" for a sporty, subcompact car, for example. Whether the final product has integrity will depend on two things: how well the concept satisfies potential customers' wants and needs and how completely the concept has been embodied in the product's details. In the most successful development organizations, "heavyweight" product managers are responsible for leading both tasks, as well as for guiding the creation of a strong product concept.

  3. The implementation of integrated care: the empirical validation of the Development Model for Integrated Care

    PubMed Central

    2011-01-01

    Background Integrated care is considered as a strategy to improve the delivery, efficiency, client outcomes and satisfaction rates of health care. To integrate the care from multiple providers into a coherent client-focused service, a large number of activities and agreements have to be implemented like streamlining information flows and patient transfers. The Development Model for Integrated care (DMIC) describes nine clusters containing in total 89 elements that contribute to the integration of care. We have empirically validated this model in practice by assessing the relevance, implementation and plans of the elements in three integrated care service settings in The Netherlands: stroke, acute myocardial infarct (AMI), and dementia. Methods Based on the DMIC, a survey was developed for integrated care coordinators. We invited all Dutch stroke and AMI-services, as well as the dementia care networks to participate, of which 84 did (response rate 83%). Data were collected on relevance, presence, and year of implementation of the 89 elements. The data analysis was done by means of descriptive statistics, Chi Square, ANOVA and Kruskal-Wallis H tests. Results The results indicate that the integrated care practice organizations in all three care settings rated the nine clusters and 89 elements of the DMIC as highly relevant. The average number of elements implemented was 50 ± 18, 42 ± 13, and 45 ± 22 for stroke, acute myocardial infarction, and dementia care services, respectively. Although the dementia networks were significantly younger, their numbers of implemented elements were comparable to those of the other services. The analyses of the implementation timelines showed that the older integrated care services had fewer plans for further implementation than the younger ones. Integrated care coordinators stated that the DMIC helped them to assess their integrated care development in practice and supported them in obtaining ideas for expanding their integrated

  4. What is an integrable quench?

    NASA Astrophysics Data System (ADS)

    Piroli, Lorenzo; Pozsgay, Balázs; Vernier, Eric

    2017-12-01

    Inspired by classical results in integrable boundary quantum field theory, we propose a definition of integrable initial states for quantum quenches in lattice models. They are defined as the states which are annihilated by all local conserved charges that are odd under space reflection. We show that this class includes the states which can be related to integrable boundary conditions in an appropriate rotated channel, in loose analogy with the picture in quantum field theory. Furthermore, we provide an efficient method to test integrability of given initial states. We revisit the recent literature of global quenches in several models and show that, in all of the cases where closed-form analytical results could be obtained, the initial state is integrable according to our definition. In the prototypical example of the XXZ spin-s chains we show that integrable states include two-site product states but also larger families of matrix product states with arbitrary bond dimension. We argue that our results could be practically useful for the study of quantum quenches in generic integrable models.

  5. Integration in psychotherapy: Reasons and challenges.

    PubMed

    Fernández-Álvarez, Héctor; Consoli, Andrés J; Gómez, Beatriz

    2016-11-01

    Although integration has been formally influencing the field of psychotherapy since the 1930s, its impact gained significant momentum during the 1980s. Practical, theoretical, and scientific reasons help to explain the growing influence of integration in psychotherapy. The field of psychotherapy is characterized by many challenges which integration may change into meaningful opportunities. Nonetheless, many obstacles remain when seeking to advance integration. To appreciate the strength of integration in psychotherapy we describe an integrative, comprehensive approach to service delivery, research, and training. We then discuss the role of integration in the future of psychotherapy. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  6. Heterogeneous Integration Technology

    DTIC Science & Technology

    2017-05-19

    Distribution A. Approved for public release; distribution unlimited. (APRS-RY-17-0383) Heterogeneous Integration Technology Dr. Burhan...2013 and 2015 [4]. ...................................... 9 Figure 3: 3D integration of similar or diverse technology components follows More Moore and...10 Figure 4: Many different technologies are used in the implementation of modern microelectronics systems can benefit from

  7. Integrating Child Health Information Systems

    PubMed Central

    Hinman, Alan R.; Eichwald, John; Linzer, Deborah; Saarlas, Kristin N.

    2005-01-01

    The Health Resources and Services Administration and All Kids Count (a national technical assistance center fostering development of integrated child health information systems) have been working together to foster development of integrated child health information systems. Activities have included: identification of key elements for successful integration of systems; development of principles and core functions for the systems; a survey of state and local integration efforts; and a conference to develop a common vision for child health information systems to meet medical care and public health needs. We provide 1 state (Utah) as an example that is well on the way to development of integrated child health information systems. PMID:16195524

  8. Optoelectronic devices toward monolithic integration

    NASA Astrophysics Data System (ADS)

    Ghergia, V.

    1992-12-01

    Starting from the present state of tl art of discrete devices up to the on going realization of monolithic semicorxtuctor integrated prototypes an overview ofoptoelectronic devices for telecom applications is given inchiding a short classification of the different kind of integrated devices. On the future perspective of IBCN distribution network some economica of hybrid and monolithic forms of integration are attempted. lnaflyashoitpresentationoftheactivitiesperformedintbefieldofmonolithic integration by EEC ESPR1T and RACE projects is reported. 1.

  9. Retrovirus Integration: Some Assembly Required?

    PubMed

    Ali, Ibraheem; Conrad, Ryan J; Ott, Melanie

    2016-12-14

    Integration is a key feature of the retroviral life cycle. This process involves packaging of the viral genome into chromatin, which is often assumed to occur as a post-integration step. In this issue of Cell Host & Microbe, Wang and colleagues (Wang et al., 2016) show that chromatinization occurs before integration, raising new questions about the role of histones in retroviral integration and transcription. Copyright © 2016. Published by Elsevier Inc.

  10. Vehicle Integrated Performance Analysis, the VIPA Experience: Reconnecting with Technical Integration

    NASA Technical Reports Server (NTRS)

    McGhee, David S.

    2005-01-01

    Today's NASA is facing significant challenges and changes. The Exploration initiative indicates a large increase in projects with limited increase in budget. The Columbia report has criticized NASA for its lack of insight and technical integration impacting its ability to provide safety. The Aldridge report is advocating NASA find new ways of doing business. Very early in the Space Launch Initiative (SLI) program a small team of engineers at MSFC were asked to propose a process for performing a system level assessment of a launch vehicle. The request was aimed primarily at providing insight and making NASA a "smart buyer." Out of this effort the VIPA team was created. The difference between the VIPA effort and many integration attempts is that VIPA focuses on using experienced people from various disciplines and a process which focuses them on a technically integrated assessment. Most previous attempts have focused on developing an all encompassing software tool. In addition, VIPA anchored its process formulation in the experience of its members and in early developmental Space Shuttle experience. The primary reference for this is NASA-TP-2001-210092, "Launch Vehicle Design Process: Characterization, Technical Integration, and Lessons Learned," and discussions with its authors. The foundations of VIPA's process are described. The VIPA team also recognized the need to drive detailed analysis earlier in the design process. Analyses and techniques typically done in later design phases, are brought forward using improved computing technology. The intent is to allow the identification of significant sensitivities, trades, and design issues much earlier in the program. This process is driven by the T-model for Technical Integration described in the aforementioned reference. VIPA's approach to performing system level technical integration is discussed in detail. Proposed definitions are offered to clarify this discussion and the general systems integration dialog. VIPA

  11. Innovation in Evaluating the Impact of Integrated Service-Delivery: The Integra Indexes of HIV and Reproductive Health Integration

    PubMed Central

    Mayhew, Susannah H.; Ploubidis, George B.; Sloggett, Andy; Church, Kathryn; Obure, Carol D.; Birdthistle, Isolde; Sweeney, Sedona; Warren, Charlotte E.; Watts, Charlotte; Vassall, Anna

    2016-01-01

    Background The body of knowledge on evaluating complex interventions for integrated healthcare lacks both common definitions of ‘integrated service delivery’ and standard measures of impact. Using multiple data sources in combination with statistical modelling the aim of this study is to develop a measure of HIV-reproductive health (HIV-RH) service integration that can be used to assess the degree of service integration, and the degree to which integration may have health benefits to clients, or reduce service costs. Methods and Findings Data were drawn from the Integra Initiative’s client flow (8,263 clients in Swaziland and 25,539 in Kenya) and costing tools implemented between 2008–2012 in 40 clinics providing RH services in Kenya and Swaziland. We used latent variable measurement models to derive dimensions of HIV-RH integration using these data, which quantified the extent and type of integration between HIV and RH services in Kenya and Swaziland. The modelling produced two clear and uncorrelated dimensions of integration at facility level leading to the development of two sub-indexes: a Structural Integration Index (integrated physical and human resource infrastructure) and a Functional Integration Index (integrated delivery of services to clients). The findings highlight the importance of multi-dimensional assessments of integration, suggesting that structural integration is not sufficient to achieve the integrated delivery of care to clients—i.e. “functional integration”. Conclusions These Indexes are an important methodological contribution for evaluating complex multi-service interventions. They help address the need to broaden traditional evaluations of integrated HIV-RH care through the incorporation of a functional integration measure, to avoid misleading conclusions on its ‘impact’ on health outcomes. This is particularly important for decision-makers seeking to promote integration in resource constrained environments. PMID:26800517

  12. PREFACE Integrability and nonlinear phenomena Integrability and nonlinear phenomena

    NASA Astrophysics Data System (ADS)

    Gómez-Ullate, David; Lombardo, Sara; Mañas, Manuel; Mazzocco, Marta; Nijhoff, Frank; Sommacal, Matteo

    2010-10-01

    Back in 1967, Clifford Gardner, John Greene, Martin Kruskal and Robert Miura published a seminal paper in Physical Review Letters which was to become a cornerstone in the theory of integrable systems. In 2006, the authors of this paper received the AMS Steele Prize. In this award the AMS pointed out that `In applications of mathematics, solitons and their descendants (kinks, anti-kinks, instantons, and breathers) have entered and changed such diverse fields as nonlinear optics, plasma physics, and ocean, atmospheric, and planetary sciences. Nonlinearity has undergone a revolution: from a nuisance to be eliminated, to a new tool to be exploited.' From this discovery the modern theory of integrability bloomed, leading scientists to a deep understanding of many nonlinear phenomena which is by no means reachable by perturbation methods or other previous tools from linear theories. Nonlinear phenomena appear everywhere in nature, their description and understanding is therefore of great interest both from the theoretical and applicative point of view. If a nonlinear phenomenon can be represented by an integrable system then we have at our disposal a variety of tools to achieve a better mathematical description of the phenomenon. This special issue is largely dedicated to investigations of nonlinear phenomena which are related to the concept of integrability, either involving integrable systems themselves or because they use techniques from the theory of integrability. The idea of this special issue originated during the 18th edition of the Nonlinear Evolution Equations and Dynamical Systems (NEEDS) workshop, held at Isola Rossa, Sardinia, Italy, 16-23 May 2009 (http://needs-conferences.net/2009/). The issue benefits from the occasion offered by the meeting, in particular by its mini-workshops programme, and contains invited review papers and contributed papers. It is worth pointing out that there was an open call for papers and all contributions were peer reviewed

  13. NASA UAS Integration into the NAS Project: Human Systems Integration

    NASA Technical Reports Server (NTRS)

    Shively, Jay

    2016-01-01

    This presentation provides an overview of the work the Human Systems Integration (HSI) sub-project has done on detect and avoid (DAA) displays while working on the UAS (Unmanned Aircraft System) Integration into the NAS project. The most recent simulation on DAA interoperability with Traffic Collision Avoidance System (TCAS) is discussed in the most detail. The relationship of the work to the larger UAS community and next steps are also detailed.

  14. Systems Integration Fact Sheet

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2016-06-01

    This fact sheet is an overview of the Systems Integration subprogram at the U.S. Department of Energy SunShot Initiative. The Systems Integration subprogram enables the widespread deployment of safe, reliable, and cost-effective solar energy technologies by addressing the associated technical and non-technical challenges. These include timely and cost-effective interconnection procedures, optimal system planning, accurate prediction of solar resources, monitoring and control of solar power, maintaining grid reliability and stability, and many more. To address the challenges associated with interconnecting and integrating hundreds of gigawatts of solar power onto the electricity grid, the Systems Integration program funds research, development, and demonstrationmore » projects in four broad, interrelated focus areas: grid performance and reliability, dispatchability, power electronics, and communications.« less

  15. Wirelessly controlled micro- and nanostructures for bioapplications

    NASA Astrophysics Data System (ADS)

    Lindo, Andre Machado

    Apresentar uma contribuicao para a caracterizacao e compreensao do comportamento hidrodinâmico da laguna Ria de Aveiro, baseada num estudo experimental e num estudo de modelacao numerica, e o objectivo deste trabalho. As caracteristicas hidrologicas da Ria de Aveiro foram investigadas atraves da realizacao de varias campanhas de amostragem, tendo sido efectuadas medicoes de altura de agua, salinidade, temperatura da agua e velocidade da corrente em varias estacoes distribuidas ao longo de quatro canais principais da laguna. None

  16. Human Rights and United States Military Humanitarian and Civic Assistance in Latin America

    DTIC Science & Technology

    2004-06-01

    hearts and minds of local populations by seeing to the provision of their basic needs, such as potable water and healthcare. These projects, many...Socialist Deputy Questions U.S. Troop Presence,” G1. 102 Ibid.; “Deputy Aguas Rejects U.S. Military Presence,” [text] Quito, Quito Radio [Spanish], 2300 GMT...online: www.humanrights- usa.net/statements/0425RtoD.htm Accessed 3 September 2003. “Deputy Aguas Rejects U.S. Military Presence,” [text] Quito, Quito

  17. Papers Selected for Presentation at the International Symposium on Remote Sensing of Environment (16th) Held at Buenos Aires, Argentina on 2-9 June 1982. Volume 2.

    DTIC Science & Technology

    1982-06-01

    ARGENTINA Oscar Dominguez and Stella Carballo .............. 355 STUDIES ON SOME URBAN PROBLEMS USING AIRBORNE REMOTE SENSORS IN SANTIAGO, CHILE ...SAN JUAN ARGENTINA) (1) Silvia Lendaro de Gianni (2,3) Enrique Uliarte (I) Centro Regional de Agua Subterrgnea (2) Universidad Nacional de San Juan act...Hidrogeol6gico para refuerzo do la provisi6n de agua " a Puerto Deseado. In4dito. - Pezzuchi, Hugo Daniel (1978) "studio Geol6gico de la zona de Lstancia Dos

  18. Archeological Investigations in Cochiti Reservoir, New Mexico. Volume 4. Adaptive Change in the Northern Rio Grande Valley.

    DTIC Science & Technology

    1979-01-01

    remains for the entire to irrigate their gardens of melons, squashes, onions. chiles . Cochiti region, sunflowers, and tomatoes (Clark 1928:234). Thus...red period Glaze decorated wares also occur in northern and are Agua Fria Glaze-on-red, San Clemente Glaze-polychrome, western Mexico and were...modified from Mera 1933) Group TyoeName Etimated Date of Manufacture (A.D. pre-A Los Padillas G-P 71300 to 1325? A Arenal G-P ?1315 to 13507 Agua Fria G/R

  19. The LACDA (Los Angeles County Drainage Area) System Recreation Study, Los Angeles County Drainage Area.

    DTIC Science & Technology

    1980-03-01

    Channel Islands and is not conveniently situ - tions, potential benefits are greatly increased by con- ated for the daily use of large numbers of people...are at least three races of birds and some plant species on the peninsula that are found nowhere else except the Channel Islands. 32. Agua Amarga Canyon...Class 3 (4,5,7) Agua Amarga Canyon is the last remaining relatively undisturbed drainage on the coastal side of the Palos Verdes Peninsula. There

  20. Pathophysiology and Toxicokinetic Studies of Blue-Green Algae Intoxication in the Swine Model

    DTIC Science & Technology

    1989-09-26

    In that study a ratio of L� of toxin to CTR infused into similar in situ rat gut loop preparations ameliorated the toxicoses and the liver weights...that had been produced and extracted from laboratory grown Anabaena flos- aguae NCR-525-17, paraoxon, or a control solution. Each of the 5 treatments was...Carmichael, W. W. (1987) Anatoxin-a(s), an 3 anticholinesterase from the cyanobacterium Anabaena flos- aguae NRC-525-17. Toxicon 25:1221. 3 Matsunaga, S

  1. Statistical Methods in Integrative Genomics

    PubMed Central

    Richardson, Sylvia; Tseng, George C.; Sun, Wei

    2016-01-01

    Statistical methods in integrative genomics aim to answer important biology questions by jointly analyzing multiple types of genomic data (vertical integration) or aggregating the same type of data across multiple studies (horizontal integration). In this article, we introduce different types of genomic data and data resources, and then review statistical methods of integrative genomics, with emphasis on the motivation and rationale of these methods. We conclude with some summary points and future research directions. PMID:27482531

  2. Quantum integrability and functional equations

    NASA Astrophysics Data System (ADS)

    Volin, Dmytro

    2010-03-01

    In this thesis a general procedure to represent the integral Bethe Ansatz equations in the form of the Reimann-Hilbert problem is given. This allows us to study in simple way integrable spin chains in the thermodynamic limit. Based on the functional equations we give the procedure that allows finding the subleading orders in the solution of various integral equations solved to the leading order by the Wiener-Hopf technics. The integral equations are studied in the context of the AdS/CFT correspondence, where their solution allows verification of the integrability conjecture up to two loops of the strong coupling expansion. In the context of the two-dimensional sigma models we analyze the large-order behavior of the asymptotic perturbative expansion. Obtained experience with the functional representation of the integral equations allowed us also to solve explicitly the crossing equations that appear in the AdS/CFT spectral problem.

  3. Intelligent multi-sensor integrations

    NASA Technical Reports Server (NTRS)

    Volz, Richard A.; Jain, Ramesh; Weymouth, Terry

    1989-01-01

    Growth in the intelligence of space systems requires the use and integration of data from multiple sensors. Generic tools are being developed for extracting and integrating information obtained from multiple sources. The full spectrum is addressed for issues ranging from data acquisition, to characterization of sensor data, to adaptive systems for utilizing the data. In particular, there are three major aspects to the project, multisensor processing, an adaptive approach to object recognition, and distributed sensor system integration.

  4. The role of two families of bacterial enzymes in putrescine synthesis from agmatine via agmatine deiminase.

    PubMed

    Landete, José M; Arena, Mario E; Pardo, Isabel; Manca de Nadra, María C; Ferrer, Sergi

    2010-12-01

    Putrescine, one of the main biogenic amines associated to microbial food spoilage, can be formed by bacteria from arginine via ornithine decarboxylase (ODC), or from agmatine via agmatine deiminase (AgDI). This study aims to correlate putrescine production from agmatine to the pathway involving N-carbamoylputrescine formation via AdDI (the aguA product) and N-carbamoylputrescine amidohydrolase (the aguB product), or putrescine carbamoyltransferase (the ptcA product) in bacteria. PCR methods were developed to detect the two genes involved in putrescine production from agmatine. Putrescine production from agmatine could be linked to the aguA and ptcA genes in Lactobacillus hilgardii X1B, Enterococcus faecalis ATCC 11700, and Bacillus cereus ATCC 14579. By contrast Lactobacillus sakei 23K was unable to produce putrescine, and although a fragment of DNA corresponding to the gene aguA was amplified, no amplification was observed for the ptcA gene. Pseudomonas aeruginosa PAO1 produces putrescine and is reported to harbour aguA and aguB genes, responsible for agmatine deiminase and N-carbamoylputrescine amidohydrolase activities. The enzyme from P. aeruginosa PAO1 that converts N-carbamoylputrescine to putrescine (the aguB product) is different from other microorganisms studied (the ptcA product). Therefore, the aguB gene from P. aeruginosa PAO1 could not be amplified with ptcA-specific primers. The aguB and ptcA genes have frequently been erroneously annotated in the past, as in fact these two enzymes are neither homologous nor analogous. Furthermore, the aguA, aguB and ptcA sequences available from GenBank were subjected to phylogenetic analysis, revealing that gram-positive bacteria harboured ptcA, whereas gram-negative bacteria harbour aguB. This paper also discusses the role of the agmatine deiminase system (AgDS) in acid stress resistance.

  5. The integrative review: updated methodology.

    PubMed

    Whittemore, Robin; Knafl, Kathleen

    2005-12-01

    The aim of this paper is to distinguish the integrative review method from other review methods and to propose methodological strategies specific to the integrative review method to enhance the rigour of the process. Recent evidence-based practice initiatives have increased the need for and the production of all types of reviews of the literature (integrative reviews, systematic reviews, meta-analyses, and qualitative reviews). The integrative review method is the only approach that allows for the combination of diverse methodologies (for example, experimental and non-experimental research), and has the potential to play a greater role in evidence-based practice for nursing. With respect to the integrative review method, strategies to enhance data collection and extraction have been developed; however, methods of analysis, synthesis, and conclusion drawing remain poorly formulated. A modified framework for research reviews is presented to address issues specific to the integrative review method. Issues related to specifying the review purpose, searching the literature, evaluating data from primary sources, analysing data, and presenting the results are discussed. Data analysis methods of qualitative research are proposed as strategies that enhance the rigour of combining diverse methodologies as well as empirical and theoretical sources in an integrative review. An updated integrative review method has the potential to allow for diverse primary research methods to become a greater part of evidence-based practice initiatives.

  6. Sixth-Order Lie Group Integrators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Forest, E.

    1990-03-01

    In this paper we present the coefficients of several 6th order symplectic integrator of the type developed by R. Ruth. To get these results we fully exploit the connection with Lie groups. This integrator, as well as all the explicit integrators of Ruth, may be used in any equation where some sort of Lie bracket is preserved. In fact, if the Lie operator governing the equation of motion is separable into two solvable parts, the Ruth integrators can be used.

  7. Integrals for IBS and beam cooling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burov, A.; /Fermilab

    Simulation of beam cooling usually requires performing certain integral transformations every time step or so, which is a significant burden on the CPU. Examples are the dispersion integrals (Hilbert transforms) in the stochastic cooling, wake fields and IBS integrals. An original method is suggested for fast and sufficiently accurate computation of the integrals. This method is applied for the dispersion integral. Some methodical aspects of the IBS analysis are discussed.

  8. Integrals for IBS and Beam Cooling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burov, A.

    Simulation of beam cooling usually requires performing certain integral transformations every time step or so, which is a significant burden on the CPU. Examples are the dispersion integrals (Hilbert transforms) in the stochastic cooling, wake fields and IBS integrals. An original method is suggested for fast and sufficiently accurate computation of the integrals. This method is applied for the dispersion integral. Some methodical aspects of the IBS analysis are discussed.

  9. IntegratedMap: a Web interface for integrating genetic map data.

    PubMed

    Yang, Hongyu; Wang, Hongyu; Gingle, Alan R

    2005-05-01

    IntegratedMap is a Web application and database schema for storing and interactively displaying genetic map data. Its Web interface includes a menu for direct chromosome/linkage group selection, a search form for selection based on mapped object location and linkage group displays. An overview display provides convenient access to the full range of mapped and anchored object types with genetic locus details, such as numbers, types and names of mapped/anchored objects displayed in a compact scrollable list box that automatically updates based on selected map location and object type. Also, multilinkage group and localized map views are available along with links that can be configured for integration with other Web resources. IntegratedMap is implemented in C#/ASP.NET and the package, including a MySQL schema creation script, is available from http://cggc.agtec.uga.edu/Data/download.asp

  10. Integrative Learning: A Grounded Theory

    ERIC Educational Resources Information Center

    Leonard, Jeannie Brown

    2012-01-01

    This article reports the findings from a study of undergraduate students in an academic program focused on integrative learning rather than interdisciplinarity. One aspect of this study included how students defined integrative learning. This participant-shaped understanding of integrative learning was broad and reflected a continuum of…

  11. System integration report

    NASA Technical Reports Server (NTRS)

    Badler, N. I.; Korein, J. D.; Meyer, C.; Manoochehri, K.; Rovins, J.; Beale, J.; Barr, B.

    1985-01-01

    Several areas that arise from the system integration issue were examined. Intersystem analysis is discussed as it relates to software development, shared data bases and interfaces between TEMPUS and PLAID, shaded graphics rendering systems, object design (BUILD), the TEMPUS animation system, anthropometric lab integration, ongoing TEMPUS support and maintenance, and the impact of UNIX and local workstations on the OSDS environment.

  12. Integrated optical motor.

    PubMed

    Kelemen, Lóránd; Valkai, Sándor; Ormos, Pál

    2006-04-20

    A light-driven micrometer-sized mechanical motor is created by laser-light-induced two-photon photopolymerization. All necessary components of the engine are built upon a glass surface by an identical procedure and include the following: a rigid mechanical framework, a rotor freely rotating on an axis, and an integrated optical waveguide carrying the actuating light to the rotor. The resulting product is a most practical stand-alone system. The light introduced into the integrated optical waveguide input of the motor provides the driving force: neither optical tweezers or even a microscope are needed for the function. The power and efficiency of the motor are evaluated. The independent unit is expected to become an important component of more complex integrated lab-on-a-chip devices.

  13. GASCAN 2 payload integration

    NASA Technical Reports Server (NTRS)

    Brown, Henry B., Jr.; Buzby, Jared G.; Doyle, Barbara J.; Wibisono, Benedict C.

    1994-01-01

    This MQP is an ongoing part of the NASA Advanced Space Design Program which examines the integration of the WPI/MITRE Get Away Special Canister (GASCan 2). GASCan 2 contains the Ionospheric Properties and Propagation, Micro-Gravity Ignition, and Rotational Fluid Flow experiments, as well as the integrated support structure. The objectives this year were to finalize the power supply system, connections for experiments, mechanical design of the IPPE's antenna, and to update the structural and vibrational analysis of the integrated support structure.

  14. A science of integration: frameworks, processes, and products in a place-based, integrative study

    USGS Publications Warehouse

    Kliskey, Andrew; Alessa, Lilian; Wandersee, Sarah; Williams, Paula; Trammell, Jamie; Powell, Jim; Grunblatt, Jess; Wipfli, Mark S.

    2017-01-01

    Integrative research is increasingly a priority within the scientific community and is a central goal for the evolving field of sustainability science. While it is conceptually attractive, its successful implementation has been challenging and recent work suggests that the move towards interdisciplinarity and transdisciplinarity in sustainability science is being only partially realized. To address this from the perspective of social-ecological systems (SES) research, we examine the process of conducting a science of integration within the Southcentral Alaska Test Case (SCTC) of Alaska-EPSCoR as a test-bed for this approach. The SCTC is part of a large, 5 year, interdisciplinary study investigating changing environments and adaptations to those changes in Alaska. In this paper, we review progress toward a science of integration and present our efforts to confront the practical issues of applying proposed integration frameworks. We: (1) define our integration framework; (2) describe the collaborative processes, including the co-development of science through stakeholder engagement and partnerships; and (3) illustrate potential products of integrative, social-ecological systems research. The approaches we use can also be applied outside of this particular framework. We highlight challenges and propose improvements for integration in sustainability science by addressing the need for common frameworks and improved contextual understanding. These insights may be useful for capacity-building for interdisciplinary projects that address complex real-world social and environmental problems.

  15. Toward Technology Integration in Mathematics Education: A Technology-Integration Course Planning Assignment

    ERIC Educational Resources Information Center

    Kersaint, Gladis

    2007-01-01

    This article describes a technology integration course planning assignment that was developed to enhance preservice teachers' technological pedagogical content knowledge (TPCK). This assignment required preservice teachers work with peers to integrate various technological tools (e.g., graphing calculators, web-based mathematics applets, etc) in a…

  16. Integrated Education in Contemporary Poland

    ERIC Educational Resources Information Center

    Apanel, Danuta

    2013-01-01

    This article presents the most important aspects, organizational principles and achievements in the field of integrated education in Poland. The author outlines the dynamics of the development of institutions of integrated education and institutions with integrated sections between 1989 and 2010. She describes the actual state of teaching…

  17. Application of the Yoshida-Ruth Techniques to Implicit Integration and Multi-Map Explicit Integration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Forest, E.; Bengtsson, J.; Reusch, M.F.

    1991-04-01

    The full power of Yoshida's technique is exploited to produce an arbitrary order implicit symplectic integrator and multi-map explicit integrator. This implicit integrator uses a characteristic function involving the force term alone. Also we point out the usefulness of the plain Ruth algorithm in computing Taylor series map using the techniques first introduced by Berz in his 'COSY-INFINITY' code.

  18. 1.31-1.55-µm Hybrid integrated optoelectronic receiver using low-loss quasi-monolithic integration technology

    NASA Astrophysics Data System (ADS)

    Luo, Yang; Huang, Yongqing; Ren, Xiaomin; Duan, Xiaofeng; Wang, Qi

    2014-01-01

    In order to integrate photonic devices with electronic devices to realize the low-loss hybrid integrated devices. A wide spectral hybrid integrated optoelectronic receiver was fabricated by using quasi-monolithic integration technology (QMIT) in this paper. It consisted of a 8.5 GHz InGaAs photodetector and a 1.25 Gbps mature transimpedance pre-amplifier (TIA) complementrary metal oxide semiconductor (CMOS) chip. The Au layer was deposited on a designed Si platform to form planar waveguide electrode which replaced a part of bonding wire, so it reduced the parasitic parameters of the optoelectronic receiver, and then enhanced high-speed response characteristics and the stability of the hybrid integrated receiver. Finally, a 3 Gbps clear open eye diagram of the hybrid integrated optoelectronic receiver was obtained.

  19. DR-Integrator: a new analytic tool for integrating DNA copy number and gene expression data.

    PubMed

    Salari, Keyan; Tibshirani, Robert; Pollack, Jonathan R

    2010-02-01

    DNA copy number alterations (CNA) frequently underlie gene expression changes by increasing or decreasing gene dosage. However, only a subset of genes with altered dosage exhibit concordant changes in gene expression. This subset is likely to be enriched for oncogenes and tumor suppressor genes, and can be identified by integrating these two layers of genome-scale data. We introduce DNA/RNA-Integrator (DR-Integrator), a statistical software tool to perform integrative analyses on paired DNA copy number and gene expression data. DR-Integrator identifies genes with significant correlations between DNA copy number and gene expression, and implements a supervised analysis that captures genes with significant alterations in both DNA copy number and gene expression between two sample classes. DR-Integrator is freely available for non-commercial use from the Pollack Lab at http://pollacklab.stanford.edu/ and can be downloaded as a plug-in application to Microsoft Excel and as a package for the R statistical computing environment. The R package is available under the name 'DRI' at http://cran.r-project.org/. An example analysis using DR-Integrator is included as supplemental material. Supplementary data are available at Bioinformatics online.

  20. Medical Group Structural Integration May Not Ensure That Care Is Integrated, From The Patient's Perspective.

    PubMed

    Kerrissey, Michaela J; Clark, Jonathan R; Friedberg, Mark W; Jiang, Wei; Fryer, Ashley K; Frean, Molly; Shortell, Stephen M; Ramsay, Patricia P; Casalino, Lawrence P; Singer, Sara J

    2017-05-01

    Structural integration is increasing among medical groups, but whether these changes yield care that is more integrated remains unclear. We explored the relationships between structural integration characteristics of 144 medical groups and perceptions of integrated care among their patients. Patients' perceptions were measured by a validated national survey of 3,067 Medicare beneficiaries with multiple chronic conditions across six domains that reflect knowledge and support of, and communication with, the patient. Medical groups' structural characteristics were taken from the National Study of Physician Organizations and included practice size, specialty mix, technological capabilities, and care management processes. Patients' survey responses were most favorable for the domain of test result communication and least favorable for the domain of provider support for medication and home health management. Medical groups' characteristics were not consistently associated with patients' perceptions of integrated care. However, compared to patients of primary care groups, patients of multispecialty groups had strong favorable perceptions of medical group staff knowledge of patients' medical histories. Opportunities exist to improve patient care, but structural integration of medical groups might not be sufficient for delivering care that patients perceive as integrated. Project HOPE—The People-to-People Health Foundation, Inc.

  1. Two Related Parametric Integrals

    ERIC Educational Resources Information Center

    Dana-Picard, T.

    2007-01-01

    Two related sequences of definite integrals are considered. By mixing hand-work, computer algebra system assistance and websurfing, fine connections can be studied between integrals and a couple of interesting sequences of integers. (Contains 4 tables.)

  2. Determination of elementary first integrals of a generalized Raychaudhuri equation by the Darboux integrability method

    NASA Astrophysics Data System (ADS)

    Choudhury, A. Ghose; Guha, Partha; Khanra, Barun

    2009-10-01

    The Darboux integrability method is particularly useful to determine first integrals of nonplanar autonomous systems of ordinary differential equations, whose associated vector fields are polynomials. In particular, we obtain first integrals for a variant of the generalized Raychaudhuri equation, which has appeared in string inspired modern cosmology.

  3. Integrating financial and strategic planning.

    PubMed

    Pivnicny, V C

    1989-09-01

    As hospitals face mounting profitability and liquidity concerns, the need to integrate strategic and financial planning also will continue to grow. This article describes a process for integrating these planning functions and the ideal organizational framework to facilitate the process. Obstacles to the integration of these planning processes also are discussed.

  4. Understanding Sensory Integration. ERIC Digest.

    ERIC Educational Resources Information Center

    DiMatties, Marie E.; Sammons, Jennifer H.

    This brief paper summarizes what is known about sensory integration and sensory integration dysfunction (DSI). It outlines evaluation of DSI, treatment approaches, and implications for parents and teachers, including compensatory strategies for minimizing the impact of DSI on a child's life. Review of origins of sensory integration theory in the…

  5. Sources and fate of antimicrobials in integrated fish-pig and non-integrated tilapia farms.

    PubMed

    Li, Kang; Liu, Liping; Zhan, Jia; Scippo, Marie-Louise; Hvidtfeldt, Kristian; Liu, Yuan; Dalsgaard, Anders

    2017-10-01

    Antimicrobial contamination in aquaculture products constitutes a food safety hazard, but little is known about the introduction and accumulation of antimicrobials in integrated fish-pig aquaculture. This study, conducted in 2013, aimed to determine the residues of 11 types of antimicrobials by UPLC-MS/MS analysis in fish feed (n=37), pig feed (n=9), pig manure (n=9), pond sediment (n=20), fish skin (n=20) and muscle tissue (n=20) sampled from integrated tilapia-pig farms, non-integrated tilapia farms and fish feed supply shops. There was a higher occurrence of antimicrobial residues in fish skin from both integrated and non-integrated farms, and in pig manure. Enrofloxacin (3.9-129.3μg/kg) and sulfadiazine (0.7-7.8μg/kg) were commonly detected in fish skin and muscle, pig manure and pond sediment from integrated farms, with different types of antimicrobials found in pig manure and tilapia samples. In non-integrated farms, sulfadiazine (2.5-89.9μg/kg) was the predominant antimicrobial detected in fish skin and muscle, fish feed and pond sediment. In general, antimicrobials seemed not to be commonly transmitted from pig to fish in tilapia-pig integrated farms, and fish feed, pig feed and pond sediment did not seem as important sources of the antimicrobials found in fish from both systems. The frequent findings of antimicrobial residues in fish skin compared with fish muscle was probably due to different pharmacokinetics in different tissue types, which have practical food safety implications since antimicrobial residues monitoring is usually performed analyzing mixed skin and fish muscle samples. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Characteristics of individuals with integrated pensions.

    PubMed

    Bender, K A

    1999-01-01

    Employer pensions that integrate benefits with Social Security have been the focus of relatively little research. Since changes in Social Security benefit levels and other program characteristics can affect the benefit levels and other features of integrated pension plans, it is important to know who is covered by these plans. This article examines the characteristics of workers covered by integrated pension plans, compared to those with nonintegrated plans and those with no pension coverage. Integrated pension plans are those that explicitly adjust their benefit structure to help compensate for the employer's contributions to the Social Security program. There are two basic integration methods used by defined benefit (DB) plans. The offset method causes a reduction in employer pension benefits by up to half of the Social Security retirement benefit; the excess rate method is characterized by an accrual rate that is lower for earnings below the Social Security taxable maximum than above it. Defined contribution (DC) pension plans can be integrated along the lines of the excess rate method. To date, research on integrated pensions has focused on plan characteristics, as reported to the Bureau of Labor Statistics (BLS) through its Employee Benefits Survey (EBS). This research has examined the prevalence of integration among full-time, private sector workers by industry, firm size, and broad occupational categories. However, because the EBS provides virtually no data on worker characteristics, analyses of the effects of pension integration on retirement benefits have used hypothetical workers, varying according to assumed levels of earnings and job tenure. This kind of analysis is not particularly helpful in examining the potential effects of changes in the Social Security program on workers' pension benefits. However, data on pension integration at the individual level are available, most recently from the Health and Retirement Study (HRS), a nationally

  7. Managing clinical integration in integrated delivery systems: a framework for action.

    PubMed

    Young, D W; Barrett, D

    1997-01-01

    An integrated delivery system (IDS) in healthcare must coordinate patient care across multiple functions, activities, and operating units. To achieve this clinical integration, senior management confronts many challenges. This paper uses a cross-functional-process (CFP) framework to discuss these challenges. There are ten CFPs that fall into three categories: planning processes (strategy formulation, program adaptation, budget formulation), organizational processes (authority and influence, client management, conflict resolution, motivation, and cultural maintenance), and measurement and reporting processes (financial and programmatic). Each process typically spans several functional units. Senior management must consider how to improve both the functioning of each CFP, as well as its "fit" with the other nine. The result can be greater clinical integration, improved cost management, and more coordinated care for enrollees.

  8. Joint-operation in water resources project in Indonesia: Integrated or non-integrated

    NASA Astrophysics Data System (ADS)

    Ophiyandri, Taufika; Istijono, Bambang; Hidayat, Benny

    2017-11-01

    The construction of large water resources infrastructure project often involved a joint-operation (JO) project between two or more construction companies. The form of JO can be grouped into two categories - an integrated type and a non-integrated type. This paper investigates the reason of forming a JO project made by companies. The specific advantages and problems of JO project is also analysed in this paper. In order to achieve the objectives, three water resources infrastructure projects were selected as case studies. Data was gathered by conducting 11 semi-structured interviews to project owners, contractor managers, and project staffs. Data was analysed by means of content analysis. It was found that the most fundamental factor to form a JO is to win a competition or tender. An integrated model is in favour because it can reduce overhead costs and has a simple management system, while a non-integrated model is selected because it can avoid a sleeping partner and make contractor more responsible for their own job.

  9. Laplace Transforms without Integration

    ERIC Educational Resources Information Center

    Robertson, Robert L.

    2017-01-01

    Calculating Laplace transforms from the definition often requires tedious integrations. This paper provides an integration-free technique for calculating Laplace transforms of many familiar functions. It also shows how the technique can be applied to probability theory.

  10. Attention modulates trans-saccadic integration.

    PubMed

    Stewart, Emma E M; Schütz, Alexander C

    2018-01-01

    With every saccade, humans must reconcile the low resolution peripheral information available before a saccade, with the high resolution foveal information acquired after the saccade. While research has shown that we are able to integrate peripheral and foveal vision in a near-optimal manner, it is still unclear which mechanisms may underpin this important perceptual process. One potential mechanism that may moderate this integration process is visual attention. Pre-saccadic attention is a well documented phenomenon, whereby visual attention shifts to the location of an upcoming saccade before the saccade is executed. While it plays an important role in other peri-saccadic processes such as predictive remapping, the role of attention in the integration process is as yet unknown. This study aimed to determine whether the presentation of an attentional distractor during a saccade impaired trans-saccadic integration, and to measure the time-course of this impairment. Results showed that presenting an attentional distractor impaired integration performance both before saccade onset, and during the saccade, in selected subjects who showed integration in the absence of a distractor. This suggests that visual attention may be a mechanism that facilitates trans-saccadic integration. Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.

  11. Teaching Integration Applications Using Manipulatives

    ERIC Educational Resources Information Center

    Bhatia, Kavita; Premadasa, Kirthi; Martin, Paul

    2014-01-01

    Calculus students' difficulties in understanding integration have been extensively studied. Research shows that the difficulty lies with students understanding of the definition of the definite integral as a limit of a Riemann sum and with the idea of accumulation inherent in integration. We have created a set of manipulatives and activities…

  12. Integrated bio-fluorescence sensor.

    PubMed

    Thrush, Evan; Levi, Ofer; Ha, Wonill; Wang, Ke; Smith, Stephen J; Harris, James S

    2003-09-26

    Due to the recent explosion in optoelectronics for telecommunication applications, novel optoelectronic sensing structures can now be realized. In this work, we explore the integration of optoelectronic components towards miniature and portable fluorescence sensors. The integration of these micro-fabricated sensors with microfluidics and capillary networks may reduce the cost and complexity of current research instruments and open up a world of new applications in portable biological analysis systems. A novel optoelectronic design that capitalizes on current vertical-cavity surface-emitting laser (VCSEL) technology is explored. Specifically, VCSELs, optical emission filters and PIN photodetectors are fabricated as part of a monolithically integrated near-infrared fluorescence detection system. High-performance lasers and photodetectors have been characterized and integrated to form a complete sensor. Experimental results show that sensor sensitivity is limited by laser background. The laser background is caused by spontaneous emission emitted from the side of the VCSEL excitation source. Laser background will limit sensitivity in most integrated sensing designs due to locating excitation sources and photodetectors in such close proximity, and methods are proposed to reduce the laser background in such designs so that practical fluorescent detection limits can be achieved.

  13. Integrated Budget Office Toolbox

    NASA Technical Reports Server (NTRS)

    Rushing, Douglas A.; Blakeley, Chris; Chapman, Gerry; Robertson, Bill; Horton, Allison; Besser, Thomas; McCarthy, Debbie

    2010-01-01

    The Integrated Budget Office Toolbox (IBOT) combines budgeting, resource allocation, organizational funding, and reporting features in an automated, integrated tool that provides data from a single source for Johnson Space Center (JSC) personnel. Using a common interface, concurrent users can utilize the data without compromising its integrity. IBOT tracks planning changes and updates throughout the year using both phasing and POP-related (program-operating-plan-related) budget information for the current year, and up to six years out. Separating lump-sum funds received from HQ (Headquarters) into separate labor, travel, procurement, Center G&A (general & administrative), and servicepool categories, IBOT creates a script that significantly reduces manual input time. IBOT also manages the movement of travel and procurement funds down to the organizational level and, using its integrated funds management feature, helps better track funding at lower levels. Third-party software is used to create integrated reports in IBOT that can be generated for plans, actuals, funds received, and other combinations of data that are currently maintained in the centralized format. Based on Microsoft SQL, IBOT incorporates generic budget processes, is transportable, and is economical to deploy and support.

  14. Aviation Data Integration System

    NASA Technical Reports Server (NTRS)

    Kulkarni, Deepak; Wang, Yao; Windrem, May; Patel, Hemil; Keller, Richard

    2003-01-01

    During the analysis of flight data and safety reports done in ASAP and FOQA programs, airline personnel are not able to access relevant aviation data for a variety of reasons. We have developed the Aviation Data Integration System (ADIS), a software system that provides integrated heterogeneous data to support safety analysis. Types of data available in ADIS include weather, D-ATIS, RVR, radar data, and Jeppesen charts, and flight data. We developed three versions of ADIS to support airlines. The first version has been developed to support ASAP teams. A second version supports FOQA teams, and it integrates aviation data with flight data while keeping identification information inaccessible. Finally, we developed a prototype that demonstrates the integration of aviation data into flight data analysis programs. The initial feedback from airlines is that ADIS is very useful in FOQA and ASAP analysis.

  15. Mass Spectral Investigation on Toxins. I. Isolation, Purification, and Characterization of Hepatotoxins from Freshwater Blue-Green Algae (Cyanobacteria) by High-Performance Liquid Chromatography and Fast Atom Bombardment Mass Spectrometric Techniques.

    DTIC Science & Technology

    1986-09-01

    analysis ’" methods in environmental samples. The hepatotoxins from laboratory cultures of M. aeruginosa Strain 7820,15 Anabena flos- aguae (A. 4flos...flos- aguae S-23-g-1l (8 lug) F1 The results from the amino acid analysis using the Llqui-Mat Analyzer are listed in Table 2. The elution times of the...Runnegar, M.T.C., and Huynh, V.L. Effec- tiveness of Activated Carbon in the Removal of Algal Toxin from Potable Water Supplies: A Pilot Plant

  16. Riego y fertirriego

    Treesearch

    R. Kasten Dumroese; Thomas D. Landis; Kim M. Wilkinson

    2012-01-01

    El agua es el factor que más puede afectar el crecimiento y la sanidad de las plantas por sí solo. Es esencial para casi todos los procesos vegetales: la fotosíntesis, el transporte de nutrientes, el crecimiento y el desarrollo celular. De hecho, del 80 al 90% del peso de un plantín es agua, por lo cual el manejo del riego es una de las tareas más trascendentes dentro...

  17. Improved system integration for integrated gasification combined cycle (IGCC) systems.

    PubMed

    Frey, H Christopher; Zhu, Yunhua

    2006-03-01

    Integrated gasification combined cycle (IGCC) systems are a promising technology for power generation. They include an air separation unit (ASU), a gasification system, and a gas turbine combined cycle power block, and feature competitive efficiency and lower emissions compared to conventional power generation technology. IGCC systems are not yet in widespread commercial use and opportunities remain to improve system feasibility via improved process integration. A process simulation model was developed for IGCC systems with alternative types of ASU and gas turbine integration. The model is applied to evaluate integration schemes involving nitrogen injection, air extraction, and combinations of both, as well as different ASU pressure levels. The optimal nitrogen injection only case in combination with an elevated pressure ASU had the highest efficiency and power output and approximately the lowest emissions per unit output of all cases considered, and thus is a recommended design option. The optimal combination of air extraction coupled with nitrogen injection had slightly worse efficiency, power output, and emissions than the optimal nitrogen injection only case. Air extraction alone typically produced lower efficiency, lower power output, and higher emissions than all other cases. The recommended nitrogen injection only case is estimated to provide annualized cost savings compared to a nonintegrated design. Process simulation modeling is shown to be a useful tool for evaluation and screening of technology options.

  18. On (scientific) integrity: conceptual clarification.

    PubMed

    Patrão Neves, Maria do Céu

    2018-06-01

    The notion of "integrity" is currently quite common and broadly recognized as complex, mostly due to its recurring and diverse application in various distinct domains such as the physical, psychic or moral, the personal or professional, that of the human being or of the totality of beings. Nevertheless, its adjectivation imprints a specific meaning, as happens in the case of "scientific integrity". This concept has been defined mostly by via negativa, by pointing out what goes against integrity, that is, through the identification of its infringements, which has also not facilitated the elaboration of an overarching and consensual code of scientific integrity. In this context, it is deemed necessary to clarify the notion of "integrity", first etymologically, recovering the original meaning of the term, and then in a specifically conceptual way, through the identification of the various meanings with which the term can be legitimately used, particularly in the domain of scientific research and innovation. These two steps are fundamental and indispensable for a forthcoming attempt at systematizing the requirements of "scientific integrity".

  19. Integration through a Card-Sort Activity

    ERIC Educational Resources Information Center

    Green, Kris; Ricca, Bernard P.

    2015-01-01

    Learning to compute integrals via the various techniques of integration (e.g., integration by parts, partial fractions, etc.) is difficult for many students. Here, we look at how students in a college level Calculus II course develop the ability to categorize integrals and the difficulties they encounter using a card sort-resort activity. Analysis…

  20. Monolithically integrated bacteriorhodopsin/semiconductor opto-electronic integrated circuit for a bio-photoreceiver.

    PubMed

    Xu, J; Bhattacharya, P; Váró, G

    2004-03-15

    The light-sensitive protein, bacteriorhodopsin (BR), is monolithically integrated with an InP-based amplifier circuit to realize a novel opto-electronic integrated circuit (OEIC) which performs as a high-speed photoreceiver. The circuit is realized by epitaxial growth of the field-effect transistors, currently used semiconductor device and circuit fabrication techniques, and selective area BR electro-deposition. The integrated photoreceiver has a responsivity of 175 V/W and linear photoresponse, with a dynamic range of 16 dB, with 594 nm photoexcitation. The dynamics of the photochemical cycle of BR has also been modeled and a proposed equivalent circuit simulates the measured BR photoresponse with good agreement.

  1. Integral Education: New Directions for Higher Learning. SUNY Series in Integral Theory

    ERIC Educational Resources Information Center

    Esbjorn-Hargens, Sean, Ed.; Reams, Jonathan, Ed.; Gunnlaugson, Olen, Ed.

    2010-01-01

    The educational challenges faced today are driving us toward a new step in the evolution of educational theory and practice. Educators are called to go beyond simply presenting alternatives, to integrating the best of mainstream and alternative approaches and taking them to the next level. "Integral Education" accomplishes this by…

  2. Authentic Integration: A Model for Integrating Mathematics and Science in the Classroom

    ERIC Educational Resources Information Center

    Treacy, Páraic; O'Donoghue, John

    2014-01-01

    Attempts at integrating mathematics and science have been made previously but no definitive, widely adopted teaching model has been developed to date. Research suggests that hands-on, practical, student-centred tasks should form a central element when designing an effective model for the integration of mathematics and science. Aided by this…

  3. Corporate Culture Assessments in Integrative Oncology: A Qualitative Case Study of Two Integrative Oncology Centers

    PubMed Central

    Mittring, Nadine; Pérard, Marion; Witt, Claudia M.

    2013-01-01

    The offer of “integrative oncology” is one option for clinics to provide safe and evidence-based complementary medicine treatments to cancer patients. As known from merger theories, corporate culture and integration models have a strong influence on the success of such integration. To identify relevant corporate culture aspects that might influence the success in two highly visible integrative oncology clinics, we interviewed physicians, nurses, practitioners, and managers. All interviews (11 in a German breast cancer clinic and 9 in an integrative medicine cancer service in the USA) were audio-recorded, transcribed and analyzed with content analysis. According to the theoretical framework of mergers, each clinic selected a different integration type (“best of both worlds” and “linking”). Nonetheless, each developed a similar corporate culture that has a strong focus on research and safe and evidence-based treatments, and fosters a holistic and patient-centered approach. Structured communication within the team and with other departments had high relevance. Research was highlighted as a way to open doors and to facilitate a more general acceptance within the hospital. Conventional physicians felt unburdened by the provision of integrative medicine service but also saw problems in the time required for scheduled treatments, which often resulted in long waiting lists. PMID:23818923

  4. Corporate culture assessments in integrative oncology: a qualitative case study of two integrative oncology centers.

    PubMed

    Mittring, Nadine; Pérard, Marion; Witt, Claudia M

    2013-01-01

    The offer of "integrative oncology" is one option for clinics to provide safe and evidence-based complementary medicine treatments to cancer patients. As known from merger theories, corporate culture and integration models have a strong influence on the success of such integration. To identify relevant corporate culture aspects that might influence the success in two highly visible integrative oncology clinics, we interviewed physicians, nurses, practitioners, and managers. All interviews (11 in a German breast cancer clinic and 9 in an integrative medicine cancer service in the USA) were audio-recorded, transcribed and analyzed with content analysis. According to the theoretical framework of mergers, each clinic selected a different integration type ("best of both worlds" and "linking"). Nonetheless, each developed a similar corporate culture that has a strong focus on research and safe and evidence-based treatments, and fosters a holistic and patient-centered approach. Structured communication within the team and with other departments had high relevance. Research was highlighted as a way to open doors and to facilitate a more general acceptance within the hospital. Conventional physicians felt unburdened by the provision of integrative medicine service but also saw problems in the time required for scheduled treatments, which often resulted in long waiting lists.

  5. Space shuttle operations integration plan

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The Operations Integration Plan is presented, which is to provide functional definition of the activities necessary to develop and integrate shuttle operating plans and facilities to support flight, flight control, and operations. It identifies the major tasks, the organizations responsible, their interrelationships, the sequence of activities and interfaces, and the resultant products related to operations integration.

  6. Continuous-Integration Laser Energy Lidar Monitor

    NASA Technical Reports Server (NTRS)

    Karsh, Jeremy

    2011-01-01

    This circuit design implements an integrator intended to allow digitization of the energy output of a pulsed laser, or the energy of a received pulse of laser light. It integrates the output of a detector upon which the laser light is incident. The integration is performed constantly, either by means of an active integrator, or by passive components.

  7. Gated integrator with signal baseline subtraction

    DOEpatents

    Wang, X.

    1996-12-17

    An ultrafast, high precision gated integrator includes an opamp having differential inputs. A signal to be integrated is applied to one of the differential inputs through a first input network, and a signal indicative of the DC offset component of the signal to be integrated is applied to the other of the differential inputs through a second input network. A pair of electronic switches in the first and second input networks define an integrating period when they are closed. The first and second input networks are substantially symmetrically constructed of matched components so that error components introduced by the electronic switches appear symmetrically in both input circuits and, hence, are nullified by the common mode rejection of the integrating opamp. The signal indicative of the DC offset component is provided by a sample and hold circuit actuated as the integrating period begins. The symmetrical configuration of the integrating circuit improves accuracy and speed by balancing out common mode errors, by permitting the use of high speed switching elements and high speed opamps and by permitting the use of a small integrating time constant. The sample and hold circuit substantially eliminates the error caused by the input signal baseline offset during a single integrating window. 5 figs.

  8. Gated integrator with signal baseline subtraction

    DOEpatents

    Wang, Xucheng

    1996-01-01

    An ultrafast, high precision gated integrator includes an opamp having differential inputs. A signal to be integrated is applied to one of the differential inputs through a first input network, and a signal indicative of the DC offset component of the signal to be integrated is applied to the other of the differential inputs through a second input network. A pair of electronic switches in the first and second input networks define an integrating period when they are closed. The first and second input networks are substantially symmetrically constructed of matched components so that error components introduced by the electronic switches appear symmetrically in both input circuits and, hence, are nullified by the common mode rejection of the integrating opamp. The signal indicative of the DC offset component is provided by a sample and hold circuit actuated as the integrating period begins. The symmetrical configuration of the integrating circuit improves accuracy and speed by balancing out common mode errors, by permitting the use of high speed switching elements and high speed opamps and by permitting the use of a small integrating time constant. The sample and hold circuit substantially eliminates the error caused by the input signal baseline offset during a single integrating window.

  9. Teaching Ideas and Activities for Classroom: Integrating Technology into the Pedagogy of Integral Calculus and the Approximation of Definite Integrals

    ERIC Educational Resources Information Center

    Caglayan, Gunhan

    2016-01-01

    The purpose of this article is to offer teaching ideas in the treatment of the definite integral concept and the Riemann sums in a technology-supported environment. Specifically, the article offers teaching ideas and activities for classroom for the numerical methods of approximating a definite integral via left- and right-hand Riemann sums, along…

  10. Review of Variable Generation Integration Charges

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Porter, K.; Fink, S.; Buckley, M.

    2013-03-01

    The growth of wind and solar generation in the United States, and the expectation of continued growth of these technologies, dictates that the future power system will be operated in a somewhat different manner because of increased variability and uncertainty. A small number of balancing authorities have attempted to determine an 'integration cost' to account for these changes to their current operating practices. Some balancing authorities directly charge wind and solar generators for integration charges, whereas others add integration charges to projected costs of wind and solar in integrated resource plans or in competitive solicitations for generation. This report reviewsmore » the balancing authorities that have calculated variable generation integration charges and broadly compares and contrasts the methodologies they used to determine their specific integration charges. The report also profiles each balancing authority and how they derived wind and solar integration charges.« less

  11. Taking Action: Ideas To Promote Technology Integration [and] Administrator's Desk Reference: Readings To Promote Technology Integration. Technology Integration: A Thematic Focus.

    ERIC Educational Resources Information Center

    Thormann, Joan, Ed.; And Others

    This guide for school administrators interested in technology integration in the curriculum was developed from discussions at the Technology Integration Seminar held in March, 1991. The guide is divided into five chapters covering various administrative responsibilities and action steps. The first chapter presents an overview and identifies…

  12. Promotion of water consumption in elementary school children in San Diego, USA and Tlaltizapan, Mexico.

    PubMed

    Elder, John P; Holub, Christina K; Arredondo, Elva M; Sánchez-Romero, Luz María; Moreno-Saracho, Jessica E; Barquera, Simón; Rivera, Juan

    2014-01-01

    Consumption of water may help promote health and prevent obesity in children by decreasing consumption of sugar-sweetened beverages. This study used evidence-based strategies to increase water consumption in Mexican-American and Mexican children. In 2012, two schools in San Diego, USA and two other in Tlaltizapan, Mexico were recruited to Agua para Niños (Water for Kids), a program designed to promote water consumption among elementary grade students. Guided by operant psychology, the intervention focused on school and classroom activities to encourage water consumption. One control and one intervention school in each country were included. Agua para Niños resulted in increases in observed water consumption and bottle possession among US and Mexican students. Teacher receptivity to the program was very positive in both countries. Agua para Niños yielded sufficiently positive behavioral changes to be used in a future fully randomized design, and to contribute to school nutrition policy changes.

  13. Curricular Integration in Pharmacy Education

    PubMed Central

    Pearson, Marion L.; Hubball, Harry T.

    2012-01-01

    This article reviews the concepts of curricular integration and integrative learning. These concepts have reemerged in contemporary higher education reforms and are crucial in pharmacy programs where students are expected to acquire the knowledge, skills, and abilities needed for competent practice in a complex environment. Enhancing integration requires negotiating obstacles, including institutional traditions of disciplinary structures and disciplinary differences in understandings of knowledge and approaches to teaching and learning; investing the time and effort to design and implement integrated curricula; and using learning-centered pedagogical strategies. Evidence supporting the value of such efforts is not compelling, as much because of insufficient research as lackluster findings. Future avenues of scholarly inquiry are suggested to evaluate curricular integration, distinguishing between the curriculum espoused by planners, the curriculum enacted by instructors, and the curriculum experienced by students. PMID:23275669

  14. Integrating Module - NEMS Documentation

    EIA Publications

    2014-01-01

    Provides an overview of the complete National Energy Modeling System (NEMS) model, and includes brief descriptions of the modules with which the Integrating Module interacts. The emphasis and focus, however, is on the structure and function of the Integrating Module of NEMS.

  15. Integrative Analysis of Omics Big Data.

    PubMed

    Yu, Xiang-Tian; Zeng, Tao

    2018-01-01

    The diversity and huge omics data take biology and biomedicine research and application into a big data era, just like that popular in human society a decade ago. They are opening a new challenge from horizontal data ensemble (e.g., the similar types of data collected from different labs or companies) to vertical data ensemble (e.g., the different types of data collected for a group of person with match information), which requires the integrative analysis in biology and biomedicine and also asks for emergent development of data integration to address the great changes from previous population-guided to newly individual-guided investigations.Data integration is an effective concept to solve the complex problem or understand the complicate system. Several benchmark studies have revealed the heterogeneity and trade-off that existed in the analysis of omics data. Integrative analysis can combine and investigate many datasets in a cost-effective reproducible way. Current integration approaches on biological data have two modes: one is "bottom-up integration" mode with follow-up manual integration, and the other one is "top-down integration" mode with follow-up in silico integration.This paper will firstly summarize the combinatory analysis approaches to give candidate protocol on biological experiment design for effectively integrative study on genomics and then survey the data fusion approaches to give helpful instruction on computational model development for biological significance detection, which have also provided newly data resources and analysis tools to support the precision medicine dependent on the big biomedical data. Finally, the problems and future directions are highlighted for integrative analysis of omics big data.

  16. An overview of the model integration process: From pre-integration assessment to testing

    EPA Science Inventory

    Integration of models requires linking models which can be developed using different tools, methodologies, and assumptions. We performed a literature review with the aim of improving our understanding of model integration process, and also presenting better strategies for buildin...

  17. NASA Integrated Network COOP

    NASA Technical Reports Server (NTRS)

    Anderson, Michael L.; Wright, Nathaniel; Tai, Wallace

    2012-01-01

    Natural disasters, terrorist attacks, civil unrest, and other events have the potential of disrupting mission-essential operations in any space communications network. NASA's Space Communications and Navigation office (SCaN) is in the process of studying options for integrating the three existing NASA network elements, the Deep Space Network, the Near Earth Network, and the Space Network, into a single integrated network with common services and interfaces. The need to maintain Continuity of Operations (COOP) after a disastrous event has a direct impact on the future network design and operations concepts. The SCaN Integrated Network will provide support to a variety of user missions. The missions have diverse requirements and include anything from earth based platforms to planetary missions and rovers. It is presumed that an integrated network, with common interfaces and processes, provides an inherent advantage to COOP in that multiple elements and networks can provide cross-support in a seamless manner. The results of trade studies support this assumption but also show that centralization as a means of achieving integration can result in single points of failure that must be mitigated. The cost to provide this mitigation can be substantial. In support of this effort, the team evaluated the current approaches to COOP, developed multiple potential approaches to COOP in a future integrated network, evaluated the interdependencies of the various approaches to the various network control and operations options, and did a best value assessment of the options. The paper will describe the trade space, the study methods, and results of the study.

  18. An Integrated Teaching Module.

    ERIC Educational Resources Information Center

    Samuel, Marie R.; Seiferth, Berniece B.

    This integrated teaching module provides elementary and junior high school teachers with a "hands-on" approach to studying the Anasazi Indian. Emphasis is on creative exploration that focuses on integrating art, music, poetry, writing, geography, dance, history, anthropology, sociology, and archaeology. Replicas of artifacts,…

  19. Six elements of integrated primary healthcare.

    PubMed

    Brown, Lynsey J; Oliver-Baxter, Jodie

    2016-03-01

    Integrated care has the potential to deliver efficiencies and improvements in patient experiences and health outcomes. Efforts towards integrated care, especially at the primary and community health levels, have increasingly been under focus, both nationally and internationally. In Australia, regional integration is a priority, and integration of care is a task for meso-level organisations such as Primary Health Networks (PHNs). This paper seeks to provide a list of elements and questions for consideration by organisations working across primary healthcare settings, looking to enact and improve the delivery of integrated care. Six elements that consistently emerged during the development of a series of rapid reviews on integrated primary healthcare in Australia are presented in this paper. The elements identified are context, governance and leadership, infrastructure, financing, engagement, and communication. They offer a starting point for reflection in the planning and practices of organisations in their drive for continuous improvements in integrated care.

  20. Energy Systems Integration News | Energy Systems Integration Facility |

    Science.gov Websites

    DOE-funded research projects that are integrating cybersecurity controls with power systems principles Management, a hardware and software system that mimics the communications, power systems, and cybersecurity

  1. Decentralized Multisensory Information Integration in Neural Systems.

    PubMed

    Zhang, Wen-Hao; Chen, Aihua; Rasch, Malte J; Wu, Si

    2016-01-13

    How multiple sensory cues are integrated in neural circuitry remains a challenge. The common hypothesis is that information integration might be accomplished in a dedicated multisensory integration area receiving feedforward inputs from the modalities. However, recent experimental evidence suggests that it is not a single multisensory brain area, but rather many multisensory brain areas that are simultaneously involved in the integration of information. Why many mutually connected areas should be needed for information integration is puzzling. Here, we investigated theoretically how information integration could be achieved in a distributed fashion within a network of interconnected multisensory areas. Using biologically realistic neural network models, we developed a decentralized information integration system that comprises multiple interconnected integration areas. Studying an example of combining visual and vestibular cues to infer heading direction, we show that such a decentralized system is in good agreement with anatomical evidence and experimental observations. In particular, we show that this decentralized system can integrate information optimally. The decentralized system predicts that optimally integrated information should emerge locally from the dynamics of the communication between brain areas and sheds new light on the interpretation of the connectivity between multisensory brain areas. To extract information reliably from ambiguous environments, the brain integrates multiple sensory cues, which provide different aspects of information about the same entity of interest. Here, we propose a decentralized architecture for multisensory integration. In such a system, no processor is in the center of the network topology and information integration is achieved in a distributed manner through reciprocally connected local processors. Through studying the inference of heading direction with visual and vestibular cues, we show that the decentralized system

  2. Decentralized Multisensory Information Integration in Neural Systems

    PubMed Central

    Zhang, Wen-hao; Chen, Aihua

    2016-01-01

    How multiple sensory cues are integrated in neural circuitry remains a challenge. The common hypothesis is that information integration might be accomplished in a dedicated multisensory integration area receiving feedforward inputs from the modalities. However, recent experimental evidence suggests that it is not a single multisensory brain area, but rather many multisensory brain areas that are simultaneously involved in the integration of information. Why many mutually connected areas should be needed for information integration is puzzling. Here, we investigated theoretically how information integration could be achieved in a distributed fashion within a network of interconnected multisensory areas. Using biologically realistic neural network models, we developed a decentralized information integration system that comprises multiple interconnected integration areas. Studying an example of combining visual and vestibular cues to infer heading direction, we show that such a decentralized system is in good agreement with anatomical evidence and experimental observations. In particular, we show that this decentralized system can integrate information optimally. The decentralized system predicts that optimally integrated information should emerge locally from the dynamics of the communication between brain areas and sheds new light on the interpretation of the connectivity between multisensory brain areas. SIGNIFICANCE STATEMENT To extract information reliably from ambiguous environments, the brain integrates multiple sensory cues, which provide different aspects of information about the same entity of interest. Here, we propose a decentralized architecture for multisensory integration. In such a system, no processor is in the center of the network topology and information integration is achieved in a distributed manner through reciprocally connected local processors. Through studying the inference of heading direction with visual and vestibular cues, we show that

  3. NEXT Single String Integration Test Results

    NASA Technical Reports Server (NTRS)

    Soulas, George C.; Patterson, Michael J.; Pinero, Luis; Herman, Daniel A.; Snyder, Steven John

    2010-01-01

    As a critical part of NASA's Evolutionary Xenon Thruster (NEXT) test validation process, a single string integration test was performed on the NEXT ion propulsion system. The objectives of this test were to verify that an integrated system of major NEXT ion propulsion system elements meets project requirements, to demonstrate that the integrated system is functional across the entire power processor and xenon propellant management system input ranges, and to demonstrate to potential users that the NEXT propulsion system is ready for transition to flight. Propulsion system elements included in this system integration test were an engineering model ion thruster, an engineering model propellant management system, an engineering model power processor unit, and a digital control interface unit simulator that acted as a test console. Project requirements that were verified during this system integration test included individual element requirements ; integrated system requirements, and fault handling. This paper will present the results of these tests, which include: integrated ion propulsion system demonstrations of performance, functionality and fault handling; a thruster re-performance acceptance test to establish baseline performance: a risk-reduction PMS-thruster integration test: and propellant management system calibration checks.

  4. Promoting research on research integrity in Canada.

    PubMed

    Master, Zubin; McDonald, Michael; Williams-Jones, Bryn

    2012-01-01

    Research on research integrity is an important element in building a strong national research integrity framework. There is a lack of empirical evidence and conceptual research on research integrity in Canada. To further strengthen and develop our system of research integrity, we believe that greater support is needed to promote research on research integrity. Research on research integrity is imperative in order to gain a richer understanding of the diversity of responsible conduct of research norms, practices, education and policies from a Canadian perspective. The knowledge gained would help in the development of an evidenced-based and responsive Canadian system of research integrity.

  5. The LEAN Payload Integration Process

    NASA Technical Reports Server (NTRS)

    Jordan, Lee P.; Young, Yancy; Rice, Amanda

    2011-01-01

    It is recognized that payload development and integration with the International Space Station (ISS) can be complex. This streamlined integration approach is a first step toward simplifying payload integration; making it easier to fly payloads on ISS, thereby increasing feasibility and interest for more research and commercial organizations to sponsor ISS payloads and take advantage of the ISS as a National Laboratory asset. The streamlined integration approach was addressed from the perspective of highly likely initial payload types to evolve from the National Lab Pathfinder program. Payloads to be accommodated by the Expedite the Processing of Experiments for Space Station (EXPRESS) Racks and Microgravity Sciences Glovebox (MSG) pressurized facilities have been addressed. It is hoped that the streamlined principles applied to these types of payloads will be analyzed and implemented in the future for other host facilities as well as unpressurized payloads to be accommodated by the EXPRESS Logistics Carrier (ELC). Further, a payload does not have to be classified as a National Lab payload in order to be processed according to the lean payload integration process; any payload that meets certain criteria can follow the lean payload integration process.

  6. Energy Systems Integration Newsletter | Energy Systems Integration Facility

    Science.gov Websites

    simulated sequences based on a model network. The competitive procurement process provided comparative , procurement help, design reviews, and now construction support. Miramar project support is part of integrated

  7. Renewable Electricity-to-Grid Integration | Energy Systems Integration

    Science.gov Websites

    distribution management system (ADMS) use cases at the ESIF's national, vendor-neutral ADMS test bed. Example use cases include: Integration of transmission-to-building operations for demand response

  8. Multisensory integration: flexible use of general operations

    PubMed Central

    van Atteveldt, Nienke; Murray, Micah M.; Thut, Gregor; Schroeder, Charles

    2014-01-01

    Research into the anatomical substrates and “principles” for integrating inputs from separate sensory surfaces has yielded divergent findings. This suggests that multisensory integration is flexible and context-dependent, and underlines the need for dynamically adaptive neuronal integration mechanisms. We propose that flexible multisensory integration can be explained by a combination of canonical, population-level integrative operations, such as oscillatory phase-resetting and divisive normalization. These canonical operations subsume multisensory integration into a fundamental set of principles as to how the brain integrates all sorts of information, and they are being used proactively and adaptively. We illustrate this proposition by unifying recent findings from different research themes such as timing, behavioral goal and experience-related differences in integration. PMID:24656248

  9. Integrated Optical Circuit Engineering

    NASA Astrophysics Data System (ADS)

    Sriram, S.

    1985-04-01

    Implementation of single-mode optical fiber systems depends largely on the availability of integrated optical components for such functions as switching, multiplexing, and modulation. The technology of integrated optics is maturing very rapidly, and its growth justifies the optimism that now exists in the optical community.

  10. Elementary Integrated Curriculum Framework

    ERIC Educational Resources Information Center

    Montgomery County Public Schools, 2010

    2010-01-01

    The Elementary Integrated Curriculum (EIC) Framework is the guiding curriculum document for the Elementary Integrated Curriculum and represents the elementary portion of the Montgomery County (Maryland) Public Schools (MCPS) Pre-K-12 Curriculum Frameworks. The EIC Framework contains the detailed indicators and objectives that describe what…

  11. Pumping approximately integrable systems

    PubMed Central

    Lange, Florian; Lenarčič, Zala; Rosch, Achim

    2017-01-01

    Weak perturbations can drive an interacting many-particle system far from its initial equilibrium state if one is able to pump into degrees of freedom approximately protected by conservation laws. This concept has for example been used to realize Bose–Einstein condensates of photons, magnons and excitons. Integrable quantum systems, like the one-dimensional Heisenberg model, are characterized by an infinite set of conservation laws. Here, we develop a theory of weakly driven integrable systems and show that pumping can induce large spin or heat currents even in the presence of integrability breaking perturbations, since it activates local and quasi-local approximate conserved quantities. The resulting steady state is qualitatively captured by a truncated generalized Gibbs ensemble with Lagrange parameters that depend on the structure but not on the overall amplitude of perturbations nor the initial state. We suggest to use spin-chain materials driven by terahertz radiation to realize integrability-based spin and heat pumps. PMID:28598444

  12. Case Studies in Environment Integration

    DTIC Science & Technology

    1991-12-01

    such as CADRE Teamwork and Frame Technology FrameMaker , are integrated. Future plans include integrating additional software development tools into...Pictures, Sabre C, and Interleaf or FrameMaker . Cad- re Technologies has announced integration agreements with Saber C and Pansophic, as well as offering...access to the Interleaf and FrameMaker documentation tools. While some of the current agreements between vendors to create tool coalitions are

  13. Visual-vestibular cue integration for heading perception: applications of optimal cue integration theory.

    PubMed

    Fetsch, Christopher R; Deangelis, Gregory C; Angelaki, Dora E

    2010-05-01

    The perception of self-motion is crucial for navigation, spatial orientation and motor control. In particular, estimation of one's direction of translation, or heading, relies heavily on multisensory integration in most natural situations. Visual and nonvisual (e.g., vestibular) information can be used to judge heading, but each modality alone is often insufficient for accurate performance. It is not surprising, then, that visual and vestibular signals converge frequently in the nervous system, and that these signals interact in powerful ways at the level of behavior and perception. Early behavioral studies of visual-vestibular interactions consisted mainly of descriptive accounts of perceptual illusions and qualitative estimation tasks, often with conflicting results. In contrast, cue integration research in other modalities has benefited from the application of rigorous psychophysical techniques, guided by normative models that rest on the foundation of ideal-observer analysis and Bayesian decision theory. Here we review recent experiments that have attempted to harness these so-called optimal cue integration models for the study of self-motion perception. Some of these studies used nonhuman primate subjects, enabling direct comparisons between behavioral performance and simultaneously recorded neuronal activity. The results indicate that humans and monkeys can integrate visual and vestibular heading cues in a manner consistent with optimal integration theory, and that single neurons in the dorsal medial superior temporal area show striking correlates of the behavioral effects. This line of research and other applications of normative cue combination models should continue to shed light on mechanisms of self-motion perception and the neuronal basis of multisensory integration.

  14. Installation Restoration Program. Phase 2. Confirmation/Quantification. Stage 2. Volume 1. Luke Air Force Base, Arizona.

    DTIC Science & Technology

    1988-06-15

    equipped with an oil/water separator. Separated oil would be collected for reuse or proper disposal, and water would be piped to the Sewage Treatment...1940’s. The STP is located on Glendale Avenue, approximately 2 miles east of the Main Base, and adjacent to the Agua Fria River as shown in Figure 1-7...flow. The effluent from the STP is discharged into a canal that flows into lagoons in the dry Agua Fria River bed. The treated efflu- ent is routinely

  15. Natural Toxins. Characterization, Pharmacology and Therapeutics: Proceedings of the World Congress on Animal, Plant and Microbial Toxins (9th) Held in Stillwater, Oklahoma on 31 July - 5 August 1988

    DTIC Science & Technology

    1988-08-01

    Argentina, Chile and the Peoples Republic of China (Skulberg, et al., 1984; Carmichael et al., 1985, Gorham and Carmichael, 1988). Not all blooms of a...Uh_. flos-aauae that occurred in lakes and ponds of New Hampshire from 1966 through 1980. Toxic cells and extracts of Avh. flos- aguae were shown to be...strain S- 2 3 -g-l (Krishnamurthy et al., 1986 a,b). The identification of a peptide toxin from A flos- aguae S-23-g-l provides the first evidence that

  16. Public health assessment for petitioned Phelps Dodge Corp Douglas Reduction Works, Douglas, Cochise County, Arizona, Region 9. Cerclis No. AZD008397143. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    The Phelps-Dodge site, a former copper-smelting operation just outside Douglas and possibly Agua Prieta, Sonora, Mexico. This site contributed to lead-contaminated surface soils in residential areas in Douglas. Exposure to the lead-contaminated soils may have contributed and/or caused elevated blood levels in children living in both Douglas, AZ and Agua Prieta, Sonora, Mexico. Past emissions from the smelter included arsenic, lead, sulfur dioxide, inhalable particulate matter, and other heavy metals. The levels detected by air monitoring were elevated above health guidelines.

  17. Generalization of the event-based Carnevale-Hines integration scheme for integrate-and-fire models.

    PubMed

    van Elburg, Ronald A J; van Ooyen, Arjen

    2009-07-01

    An event-based integration scheme for an integrate-and-fire neuron model with exponentially decaying excitatory synaptic currents and double exponential inhibitory synaptic currents has been introduced by Carnevale and Hines. However, the integration scheme imposes nonphysiological constraints on the time constants of the synaptic currents, which hamper its general applicability. This letter addresses this problem in two ways. First, we provide physical arguments demonstrating why these constraints on the time constants can be relaxed. Second, we give a formal proof showing which constraints can be abolished. As part of our formal proof, we introduce the generalized Carnevale-Hines lemma, a new tool for comparing double exponentials as they naturally occur in many cascaded decay systems, including receptor-neurotransmitter dissociation followed by channel closing. Through repeated application of the generalized lemma, we lift most of the original constraints on the time constants. Thus, we show that the Carnevale-Hines integration scheme for the integrate-and-fire model can be employed for simulating a much wider range of neuron and synapse types than was previously thought.

  18. Wind Integration Data Sets | Grid Modernization | NREL

    Science.gov Websites

    Wind Integration Data Sets Wind Integration Data Sets NREL's wind integration data sets provide the Integration Data Sets Ten-minute time-series wind data for 2004, 2005, and 2006 to help energy professionals perform wind integration studies and estimate power production from hypothetical wind power plants. Access

  19. Integrated support structure

    NASA Technical Reports Server (NTRS)

    Bruneau, Stephen D.; Campbell, John T.; Struven, Christopher A.

    1990-01-01

    This Major Qualifying Project is part of the Advanced Space Design Program at WPI. The goal is to design a support structure for a NASA GetAway Special experimental canister. The payload integration, weight, volume, and structural integrity of the canister as specified by NASA guidelines were studied. The end result is a complete set of design drawings with interface drawings and data to specify the design and leave a base on which the next group can concentrate.

  20. Integration and Beyond

    PubMed Central

    Stead, William W.; Miller, Randolph A.; Musen, Mark A.; Hersh, William R.

    2000-01-01

    The vision of integrating information—from a variety of sources, into the way people work, to improve decisions and process—is one of the cornerstones of biomedical informatics. Thoughts on how this vision might be realized have evolved as improvements in information and communication technologies, together with discoveries in biomedical informatics, and have changed the art of the possible. This review identified three distinct generations of “integration” projects. First-generation projects create a database and use it for multiple purposes. Second-generation projects integrate by bringing information from various sources together through enterprise information architecture. Third-generation projects inter-relate disparate but accessible information sources to provide the appearance of integration. The review suggests that the ideas developed in the earlier generations have not been supplanted by ideas from subsequent generations. Instead, the ideas represent a continuum of progress along the three dimensions of workflow, structure, and extraction. PMID:10730596

  1. RADIATION INTEGRATOR

    DOEpatents

    Glass, F.M.; Wilson, H.N.

    1959-02-17

    Radiation detecting and measuring systems, particularly a compact, integrating, background monitor, are discussed. One of the principal features of the system is the use of an electrometer tube where the input of the tube is directly connected to an electrode of the radiation detector and a capacitor is coupled to the tube input. When a predetermined quantity of radiation has been integrated, a trigger signal is fed to a recorder and a charge is delivered to the capacitor to render the tube inoperative. The capacitor is then recharged for the next period of operation. With this arrangement there is a substantial reduction in lead lengths and the principal components may be enclosed and hermetically sealed to insure low leakage.

  2. UAS Integration in the NAS Project: Integrated Test and Evaluation (IT&E) Flight Test 3. Revision E

    NASA Technical Reports Server (NTRS)

    Marston, Michael

    2015-01-01

    The desire and ability to fly Unmanned Aircraft Systems (UAS) in the National Airspace System (NAS) is of increasing urgency. The application of unmanned aircraft to perform national security, defense, scientific, and emergency management are driving the critical need for less restrictive access by UAS to the NAS. UAS represent a new capability that will provide a variety of services in the government (public) and commercial (civil) aviation sectors. The growth of this potential industry has not yet been realized due to the lack of a common understanding of what is required to safely operate UAS in the NAS. NASA's UAS Integration into the NAS Project is conducting research in the areas of Separation Assurance/Sense and Avoid Interoperability, Human Systems Integration (HSI), and Communication to support reducing the barriers of UAS access to the NAS. This research is broken into two research themes namely, UAS Integration and Test Infrastructure. UAS Integration focuses on airspace integration procedures and performance standards to enable UAS integration in the air transportation system, covering Sense and Avoid (SAA) performance standards, command and control performance standards, and human systems integration. The focus of Test Infrastructure is to enable development and validation of airspace integration procedures and performance standards, including the integrated test and evaluation. In support of the integrated test and evaluation efforts, the Project will develop an adaptable, scalable, and schedulable relevant test environment capable of evaluating concepts and technologies for unmanned aircraft systems to safely operate in the NAS. To accomplish this task, the Project will conduct a series of Human-in-the-Loop and Flight Test activities that integrate key concepts, technologies and/or procedures in a relevant air traffic environment. Each of the integrated events will build on the technical achievements, fidelity and complexity of the previous tests and

  3. Semantic Web meets Integrative Biology: a survey.

    PubMed

    Chen, Huajun; Yu, Tong; Chen, Jake Y

    2013-01-01

    Integrative Biology (IB) uses experimental or computational quantitative technologies to characterize biological systems at the molecular, cellular, tissue and population levels. IB typically involves the integration of the data, knowledge and capabilities across disciplinary boundaries in order to solve complex problems. We identify a series of bioinformatics problems posed by interdisciplinary integration: (i) data integration that interconnects structured data across related biomedical domains; (ii) ontology integration that brings jargons, terminologies and taxonomies from various disciplines into a unified network of ontologies; (iii) knowledge integration that integrates disparate knowledge elements from multiple sources; (iv) service integration that build applications out of services provided by different vendors. We argue that IB can benefit significantly from the integration solutions enabled by Semantic Web (SW) technologies. The SW enables scientists to share content beyond the boundaries of applications and websites, resulting into a web of data that is meaningful and understandable to any computers. In this review, we provide insight into how SW technologies can be used to build open, standardized and interoperable solutions for interdisciplinary integration on a global basis. We present a rich set of case studies in system biology, integrative neuroscience, bio-pharmaceutics and translational medicine, to highlight the technical features and benefits of SW applications in IB.

  4. Techniques for integrating -omics data.

    PubMed

    Akula, Siva Prasad; Miriyala, Raghava Naidu; Thota, Hanuman; Rao, Allam Appa; Gedela, Srinubabu

    2009-01-01

    The challenge for -omics research is to tackle the problem of fragmentation of knowledge by integrating several sources of heterogeneous information into a coherent entity. It is widely recognized that successful data integration is one of the keys to improve productivity for stored data. Through proper data integration tools and algorithms, researchers may correlate relationships that enable them to make better and faster decisions. The need for data integration is essential for present -omics community, because -omics data is currently spread world wide in wide variety of formats. These formats can be integrated and migrated across platforms through different techniques and one of the important techniques often used is XML. XML is used to provide a document markup language that is easier to learn, retrieve, store and transmit. It is semantically richer than HTML. Here, we describe bio warehousing, database federation, controlled vocabularies and highlighting the XML application to store, migrate and validate -omics data.

  5. On an Integral with Two Branch Points

    ERIC Educational Resources Information Center

    de Oliveira, E. Capelas; Chiacchio, Ary O.

    2006-01-01

    The paper considers a class of real integrals performed by using a convenient integral in the complex plane. A complex integral containing a multi-valued function with two branch points is transformed into another integral containing a pole and a unique branch point. As a by-product we obtain a new class of integrals which can be calculated in a…

  6. Process and information integration via hypermedia

    NASA Technical Reports Server (NTRS)

    Hammen, David G.; Labasse, Daniel L.; Myers, Robert M.

    1990-01-01

    Success stories for advanced automation prototypes abound in the literature but the deployments of practical large systems are few in number. There are several factors that militate against the maturation of such prototypes into products. Here, the integration of advanced automation software into large systems is discussed. Advanced automation systems tend to be specific applications that need to be integrated and aggregated into larger systems. Systems integration can be achieved by providing expert user-developers with verified tools to efficiently create small systems that interface to large systems through standard interfaces. The use of hypermedia as such a tool in the context of the ground control centers that support Shuttle and space station operations is explored. Hypermedia can be an integrating platform for data, conventional software, and advanced automation software, enabling data integration through the display of diverse types of information and through the creation of associative links between chunks of information. Further, hypermedia enables process integration through graphical invoking of system functions. Through analysis and examples, researchers illustrate how diverse information and processing paradigms can be integrated into a single software platform.

  7. Alpha LAMP Integration Facility

    NASA Technical Reports Server (NTRS)

    Oshiro, Richard; Sowers, Dennis; Gargiulo, Joe; Mcgahey, Mark

    1994-01-01

    This paper describes the activity recently completed to meet the simulated space environment requirements for the ground-based testing of an integrated Space Based Laser (SBL) system experiment. The need to maintain optical alignment in the challenging dynamic environment of the pressure recovery system required to simulate space dominated the design requirements. A robust system design was established which minimized the total program costs, most notably by reducing the cost of integrating the components of the experiment. The components of the experiment are integrated on an optical bench in a clean area adjacent to the vacuum chamber and moved on air bearings into the chamber for testing.

  8. From integrative bioethics to pseudoscience.

    PubMed

    Bracanović, Tomislav

    2012-12-01

    Integrative bioethics is a brand of bioethics conceived and propagated by a group of Croatian philosophers and other scholars. This article discusses and shows that the approach encounters several serious difficulties. In criticizing certain standard views on bioethics and in presenting their own, the advocates of integrative bioethics fall into various conceptual confusions and inconsistencies. Although presented as a project that promises to deal with moral dilemmas created by modern science and technology, integrative bioethics does not contain the slightest normativity or action-guiding capacity. Portrayed as a scientific and interdisciplinary enterprise, integrative bioethics displays a large number of pseudoscientific features that throw into doubt its overall credibility. © 2012 Blackwell Publishing Ltd.

  9. The MIST /MIUS Integration and Subsystems Test/ laboratory - A testbed for the MIUS /Modular Integrated Utility System/ program

    NASA Technical Reports Server (NTRS)

    Beckham, W. S., Jr.; Keune, F. A.

    1974-01-01

    The MIUS (Modular Integrated Utility System) concept is to be an energy-conserving, economically feasible, integrated community utility system to provide five necessary services: electricity generation, space heating and air conditioning, solid waste processing, liquid waste processing, and residential water purification. The MIST (MIUS Integration and Subsystem Test) integrated system testbed constructed at the Johnson Space Center in Houston includes subsystems for power generation, heating, ventilation, and air conditioning (HVAC), wastewater management, solid waste management, and control and monitoring. The key design issues under study include thermal integration and distribution techniques, thermal storage, integration of subsystems controls and displays, incinerator performance, effluent characteristics, and odor control.

  10. Measuring Integrated Information from the Decoding Perspective

    PubMed Central

    Oizumi, Masafumi; Amari, Shun-ichi; Yanagawa, Toru; Fujii, Naotaka; Tsuchiya, Naotsugu

    2016-01-01

    Accumulating evidence indicates that the capacity to integrate information in the brain is a prerequisite for consciousness. Integrated Information Theory (IIT) of consciousness provides a mathematical approach to quantifying the information integrated in a system, called integrated information, Φ. Integrated information is defined theoretically as the amount of information a system generates as a whole, above and beyond the amount of information its parts independently generate. IIT predicts that the amount of integrated information in the brain should reflect levels of consciousness. Empirical evaluation of this theory requires computing integrated information from neural data acquired from experiments, although difficulties with using the original measure Φ precludes such computations. Although some practical measures have been previously proposed, we found that these measures fail to satisfy the theoretical requirements as a measure of integrated information. Measures of integrated information should satisfy the lower and upper bounds as follows: The lower bound of integrated information should be 0 and is equal to 0 when the system does not generate information (no information) or when the system comprises independent parts (no integration). The upper bound of integrated information is the amount of information generated by the whole system. Here we derive the novel practical measure Φ* by introducing a concept of mismatched decoding developed from information theory. We show that Φ* is properly bounded from below and above, as required, as a measure of integrated information. We derive the analytical expression of Φ* under the Gaussian assumption, which makes it readily applicable to experimental data. Our novel measure Φ* can generally be used as a measure of integrated information in research on consciousness, and also as a tool for network analysis on diverse areas of biology. PMID:26796119

  11. Knowledge exchange and integrated services: experiences from an integrated community intellectual (learning) disability service for adults.

    PubMed

    Farrington, C; Clare, I C H; Holland, A J; Barrett, M; Oborn, E

    2015-03-01

    This paper examines knowledge exchange dynamics in a specialist integrated intellectual (learning) disability service, comprising specialist healthcare provision with social care commissioning and management, and considers their significance in terms of integrated service delivery. A qualitative study focusing on knowledge exchange and integrated services. Semi-structured interviews (n = 25) were conducted with members of an integrated intellectual disability service in England regarding their perceptions of knowledge exchange within the service and the way in which knowledge exchange impinges on the operation of the integrated service. Exchange of 'explicit' (codifiable) knowledge between health and care management components of the service is problematic because of a lack of integrated clinical governance and related factors such as IT and care record systems and office arrangements. Team meetings and workplace interactions allowed for informal exchange of explicit and 'tacit' (non-codifiable) knowledge, but presented challenges in terms of knowledge exchange completeness and sustainability. Knowledge exchange processes play an important role in the functioning of integrated services incorporating health and care management components. Managers need to ensure that knowledge exchange processes facilitate both explicit and tacit knowledge exchange and do not rely excessively on informal, 'ad hoc' interactions. Research on integrated services should take account of micro-scale knowledge exchange dynamics and relationships between social dynamics and physical factors. © 2014 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

  12. Integrated care information technology.

    PubMed

    Rowe, Ian; Brimacombe, Phil

    2003-02-21

    Counties Manukau District Health Board (CMDHB) uses information technology (IT) to drive its Integrated Care strategy. IT enables the sharing of relevant health information between care providers. This information sharing is critical to closing the gaps between fragmented areas of the health system. The tragic case of James Whakaruru demonstrates how people have been falling through those gaps. The starting point of the Integrated Care strategic initiative was the transmission of electronic discharges and referral status messages from CMDHB's secondary provider, South Auckland Health (SAH), to GPs in the district. Successful pilots of a Well Child system and a diabetes disease management system embracing primary and secondary providers followed this. The improved information flowing from hospital to GPs now enables GPs to provide better management for their patients. The Well Child system pilot helped improve reported immunization rates in a high health need area from 40% to 90%. The diabetes system pilot helped reduce the proportion of patients with HbA1c rang:9 from 47% to 16%. IT has been implemented as an integral component of an overall Integrated Care strategic initiative. Within this context, Integrated Care IT has helped to achieve significant improvements in care outcomes, broken down barriers between health system silos, and contributed to the establishment of a system of care continuum that is better for patients.

  13. Design of integrated pitch axis for autopilot/autothrottle and integrated lateral axis for autopilot/yaw damper for NASA TSRV airplane using integral LQG methodology

    NASA Technical Reports Server (NTRS)

    Kaminer, Isaac; Benson, Russell A.; Coleman, Edward E.; Ebrahimi, Yaghoob S.

    1990-01-01

    Two designs are presented for control systems for the NASA Transport System Research Vehicle (TSRV) using integral Linear Quadratic Gaussian (LQG) methodology. The first is an integrated longitudinal autopilot/autothrottle design and the second design is an integrated lateral autopilot/yaw damper/sideslip controller design. It is shown that a systematic top-down approach to a complex design problem combined with proper application of modern control synthesis techniques yields a satisfactory solution in a reasonable period of time.

  14. Monolithically integrated self-rolled-up microtube-based vertical coupler for three-dimensional photonic integration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yu, Xin; Arbabi, Ehsan; Goddard, Lynford L.

    2015-07-20

    We demonstrate a self-rolled-up microtube-based vertical photonic coupler monolithically integrated on top of a ridge waveguide to achieve three-dimensional (3D) photonic integration. The fabrication process is fully compatible with standard planar silicon processing technology. Strong light coupling between the vertical coupler and the ridge waveguide was observed experimentally, which may provide an alternative route for 3D heterogeneous photonic integration. The highest extinction ratio observed in the transmission spectrum passing through the ridge waveguide was 23 dB.

  15. Academic Research Integration System

    ERIC Educational Resources Information Center

    Surugiu, Iula; Velicano, Manole

    2008-01-01

    This paper comprises results concluding the research activity done so far regarding enhanced web services and system integration. The objective of the paper is to define the software architecture for a coherent framework and methodology for enhancing existing web services into an integrated system. This document presents the research work that has…

  16. Soldering Tool for Integrated Circuits

    NASA Technical Reports Server (NTRS)

    Takahashi, Ted H.

    1987-01-01

    Many connections soldered simultaneously in confined spaces. Improved soldering tool bonds integrated circuits onto printed-circuit boards. Intended especially for use with so-called "leadless-carrier" integrated circuits.

  17. Integration and the performance of healthcare networks:do integration strategies enhance efficiency, profitability, and image?

    PubMed Central

    Wan, Thomas T.H.; Ma, Allen; Y.J.Lin, Blossom

    2001-01-01

    Abstract Purpose This study examines the integration effects on efficiency and financial viability of the top 100 integrated healthcare networks (IHNs) in the United States. Theory A contingency- strategic theory is used to identify the relationship of IHNs' performance to their structural and operational characteristics and integration strategies. Methods The lists of the top 100 IHNs ranked in two years, 1998 and 1999, by the SMG Marketing Group were merged to create a database for the study. Multiple indicators were used to examine the relationship between IHNs' characteristics and their performance in efficiency and financial viability. A path analytical model was developed and validated by the Mplus statistical program. Factors influencing the top 100 IHNs' images, represented by attaining ranking among the top 100 in two consecutive years, were analysed. Results and conclusion No positive associations were found between integration and network performance in efficiency or profits. Longitudinal data are needed to investigate the effect of integration on healthcare networks' financial performance. PMID:16896405

  18. Highly Integrated Spinning Projectile (HISP)

    DTIC Science & Technology

    1992-02-06

    At A A , AlAA 92-1214 HIGHLY INTEGRATED SPINNING PROJECTILE (HISP) G.R. Legters D.P. Lianos R.G. Brosch Senior Scientist, SAIC Senior Engineer...Integrated Spinning Projectile (HISP) Personal Author: Legters , G.R.; Lianos, D.P.; Brosch, R.G. Corporate Author Or Publisher: SAIC, Melbourne Beach...000001 Record ID: 26099 Source of Document: AIAA AIAA-92-1214 HIGHLY INTEGRATED SPINNING PROJECTILE (HISP) 3» en ZO O G. R. Legters Senior

  19. Integrative Cardiac Health Project (ICHP)

    DTIC Science & Technology

    2017-04-01

    AWARD NUMBER: W81XWH-16-2-0007 TITLE: Integrative Cardiac Health Project (ICHP) PRINCIPAL INVESTIGATOR: COL (Ret) Marina N. Vernalis, MC, USA...2017 4. TITLE AND SUBTITLE Integrative Cardiac Health Project (ICHP) 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-16-2-0007 5c. PROGRAM ELEMENT...Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT The Integrative Cardiac Health Project (ICHP) aims to lead the way in Cardiovascular Disease (CVD

  20. Integrated Avionics System (IAS), Integrating 3-D Technology On A Spacecraft Panel

    NASA Technical Reports Server (NTRS)

    Hunter, Don J.; Halpert, Gerald

    1999-01-01

    As spacecraft designs converge toward miniaturization, and with the volumetric and mass challenges placed on avionics, programs will continue to advance the "state of the art" in spacecraft system development with new challenges to reduce power, mass and volume. Traditionally, the trend is to focus on high-density 3-D packaging technologies. Industry has made significant progress in 3-D technologies, and other related internal and external interconnection schemes. Although new technologies have improved packaging densities, a system packaging architecture is required that not only reduces spacecraft volume and mass budgets, but increase integration efficiencies, provide modularity and flexibility to accommodate multiple missions while maintaining a low recurring cost. With these challenges in mind, a novel system packaging approach incorporates solutions that provide broader environmental applications, more flexible system interconnectivity, scalability, and simplified assembly test and integration schemes. The Integrated Avionics System (IAS) provides for a low-mass, modular distributed or centralized packaging architecture which combines ridged-flex technologies, high-density COTS hardware and a new 3-D mechanical packaging approach, Horizontal Mounted Cube (HMC). This paper will describe the fundamental elements of the IAS, HMC hardware design, system integration and environmental test results.

  1. Algebraic-geometry approach to integrability of birational plane mappings. Integrable birational quadratic reversible mappings. I

    NASA Astrophysics Data System (ADS)

    Rerikh, K. V.

    1998-02-01

    Using classic results of algebraic geometry for birational plane mappings in plane CP 2 we present a general approach to algebraic integrability of autonomous dynamical systems in C 2 with discrete time and systems of two autonomous functional equations for meromorphic functions in one complex variable defined by birational maps in C 2. General theorems defining the invariant curves, the dynamics of a birational mapping and a general theorem about necessary and sufficient conditions for integrability of birational plane mappings are proved on the basis of a new idea — a decomposition of the orbit set of indeterminacy points of direct maps relative to the action of the inverse mappings. A general method of generating integrable mappings and their rational integrals (invariants) I is proposed. Numerical characteristics Nk of intersections of the orbits Φn- kOi of fundamental or indeterminacy points Oi ɛ O ∩ S, of mapping Φn, where O = { O i} is the set of indeterminacy points of Φn and S is a similar set for invariant I, with the corresponding set O' ∩ S, where O' = { O' i} is the set of indeterminacy points of inverse mapping Φn-1, are introduced. Using the method proposed we obtain all nine integrable multiparameter quadratic birational reversible mappings with the zero fixed point and linear projective symmetry S = CΛC-1, Λ = diag(±1), with rational invariants generated by invariant straight lines and conics. The relations of numbers Nk with such numerical characteristics of discrete dynamical systems as the Arnold complexity and their integrability are established for the integrable mappings obtained. The Arnold complexities of integrable mappings obtained are determined. The main results are presented in Theorems 2-5, in Tables 1 and 2, and in Appendix A.

  2. System integration case study : FAST-TRAC : preliminary IV deliverable : #2-systems integration case study

    DOT National Transportation Integrated Search

    1999-02-12

    This report focuses on the system integration aspect of the Transportation Information Management System (TIMS), a component of the FAST-TRAC project. The TIMS functions as the center of a communications network which integrates advanced traffic cont...

  3. Contact Hamiltonian systems and complete integrability

    NASA Astrophysics Data System (ADS)

    Visinescu, Mihai

    2017-12-01

    We summarize recent results on the integrability of Hamiltonian systems on contact manifolds. We explain how to extend the classical formulation of action-angle variables to contact integrable systems. Using the Jacobi brackets defined on contact manifolds, we discuss the commutativity of first integrals for contact Hamiltonian systems and present the construction of generalized contact action-angle variables. We illustrate the integrability in the contact geometry on the five-dimensional Sasaki-Einstein spaces T1,1 and Yp,q.

  4. Integrative oncology: an overview.

    PubMed

    Deng, Gary; Cassileth, Barrie

    2014-01-01

    Integrative oncology, the diagnosis-specific field of integrative medicine, addresses symptom control with nonpharmacologic therapies. Known commonly as "complementary therapies" these are evidence-based adjuncts to mainstream care that effectively control physical and emotional symptoms, enhance physical and emotional strength, and provide patients with skills enabling them to help themselves throughout and following mainstream cancer treatment. Integrative or complementary therapies are rational and noninvasive. They have been subjected to study to determine their value, to document the problems they ameliorate, and to define the circumstances under which such therapies are beneficial. Conversely, "alternative" therapies typically are promoted literally as such; as actual antitumor treatments. They lack biologic plausibility and scientific evidence of safety and efficacy. Many are outright fraudulent. Conflating these two very different categories by use of the convenient acronym "CAM," for "complementary and alternative therapies," confuses the issue and does a substantial disservice to patients and medical professionals. Complementary and integrative modalities have demonstrated safety value and benefits. If the same were true for "alternatives," they would not be "alternatives." Rather, they would become part of mainstream cancer care. This manuscript explores the medical and sociocultural context of interest in integrative oncology as well as in "alternative" therapies, reviews commonly-asked patient questions, summarizes research results in both categories, and offers recommendations to help guide patients and family members through what is often a difficult maze. Combining complementary therapies with mainstream oncology care to address patients' physical, psychologic and spiritual needs constitutes the practice of integrative oncology. By recommending nonpharmacologic modalities that reduce symptom burden and improve quality of life, physicians also enable

  5. Clinical Strategies for Integrating Medication Interventions Into Behavioral Treatment for Adolescent ADHD: The Medication Integration Protocol

    PubMed Central

    Hogue, Aaron; Bobek, Molly; Tau, Gregory Z.; Levin, Frances R.

    2014-01-01

    Attention-Deficit/Hyperactivity Disorder (ADHD) is highly prevalent among adolescents enrolled in behavioral health services but remains undertreated in this age group. Also the first-line treatment for adolescent ADHD, stimulant medication, is underutilized in routine practice. This article briefly describes three behavioral interventions designed to promote stronger integration of medication interventions into treatment planning for adolescent ADHD: family ADHD psychoeducation, family-based medication decision-making, and behavior therapist leadership in coordinating medication integration. It then introduces the Medication Integration Protocol (MIP), which incorporates all three interventions into a five-task protocol: ADHD Assessment and Medication Consult; ADHD Psychoeducation and Client Acceptance; ADHD Symptoms and Family Relations; ADHD Medication and Family Decision-Making; and Medication Management and Integration Planning. The article concludes by highlighting what behavior therapists should know about best practices for medication integration across diverse settings and populations: integrating medication interventions into primary care, managing medication priorities and polypharmacy issues for adolescents with multiple diagnoses, providing ADHD medications to adolescent substance users, and the compatibility of MIP intervention strategies with everyday practice conditions. PMID:25505817

  6. Clinical Strategies for Integrating Medication Interventions Into Behavioral Treatment for Adolescent ADHD: The Medication Integration Protocol.

    PubMed

    Hogue, Aaron; Bobek, Molly; Tau, Gregory Z; Levin, Frances R

    2014-10-01

    Attention-Deficit/Hyperactivity Disorder (ADHD) is highly prevalent among adolescents enrolled in behavioral health services but remains undertreated in this age group. Also the first-line treatment for adolescent ADHD, stimulant medication, is underutilized in routine practice. This article briefly describes three behavioral interventions designed to promote stronger integration of medication interventions into treatment planning for adolescent ADHD: family ADHD psychoeducation, family-based medication decision-making, and behavior therapist leadership in coordinating medication integration. It then introduces the Medication Integration Protocol (MIP), which incorporates all three interventions into a five-task protocol: ADHD Assessment and Medication Consult; ADHD Psychoeducation and Client Acceptance; ADHD Symptoms and Family Relations; ADHD Medication and Family Decision-Making; and Medication Management and Integration Planning. The article concludes by highlighting what behavior therapists should know about best practices for medication integration across diverse settings and populations: integrating medication interventions into primary care, managing medication priorities and polypharmacy issues for adolescents with multiple diagnoses, providing ADHD medications to adolescent substance users, and the compatibility of MIP intervention strategies with everyday practice conditions.

  7. Integrated versus non-integrated orbital implants for treating anophthalmic sockets.

    PubMed

    Schellini, Silvana; El Dib, Regina; Silva, Leandro Re; Farat, Joyce G; Zhang, Yuqing; Jorge, Eliane C

    2016-11-07

    Anophthalmia is the absence of one or both eyes, and it can be congenital (i.e. a birth defect) or acquired later in life. There are two main types of orbital implant: integrated, whereby the implant receives a blood supply from the body that allows for the integration of the prosthesis within the tissue; and non-integrated, where the implant remains separate. Despite the remarkable progress in anophthalmic socket reconstruction and in the development of various types of implants, there are still uncertainties about the real roles of integrated (hydroxyapatite (HA), porous polyethylene (PP), composites) and non-integrated (polymethylmethacrylate (PMMA)/acrylic and silicone) orbital implants in anophthalmic socket treatment. To assess the effects of integrated versus non-integrated orbital implants for treating anophthalmic sockets. We searched CENTRAL (which contains the Cochrane Eyes and Vision Trials Register) (2016, Issue 7), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to August 2016), Embase (January 1980 to August 2016), Latin American and Caribbean Health Sciences Literature Database (LILACS) (1982 to August 2016), the ISRCTN registry (www.isrctn.com/editAdvancedSearch), ClinicalTrials.gov (www.clinicaltrials.gov), and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 8 August 2016. Randomised controlled trials (RCTs) and quasi-RCTs of integrated and non-integrated orbital implants for treating anophthalmic sockets. Two authors independently selected relevant trials, assessed methodological quality and extracted data. We included three studies with a total of 284 participants (250 included in analysis). The studies were conducted in India, Iran and the Netherlands. The three

  8. The Arithmetic of Emotion: Integration of Incidental and Integral Affect in Judgments and Decisions

    PubMed Central

    Västfjäll, Daniel; Slovic, Paul; Burns, William J.; Erlandsson, Arvid; Koppel, Lina; Asutay, Erkin; Tinghög, Gustav

    2016-01-01

    Research has demonstrated that two types of affect have an influence on judgment and decision making: incidental affect (affect unrelated to a judgment or decision such as a mood) and integral affect (affect that is part of the perceiver’s internal representation of the option or target under consideration). So far, these two lines of research have seldom crossed so that knowledge concerning their combined effects is largely missing. To fill this gap, the present review highlights differences and similarities between integral and incidental affect. Further, common and unique mechanisms that enable these two types of affect to influence judgment and choices are identified. Finally, some basic principles for affect integration when the two sources co-occur are outlined. These mechanisms are discussed in relation to existing work that has focused on incidental or integral affect but not both. PMID:27014136

  9. Energy Systems Integration: Demonstrating Distributed Resource Communications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2017-01-01

    Overview fact sheet about the Electric Power Research Institute (EPRI) and Schneider Electric Integrated Network Testbed for Energy Grid Research and Technology Experimentation (INTEGRATE) project at the Energy Systems Integration Facility. INTEGRATE is part of the U.S. Department of Energy's Grid Modernization Initiative.

  10. 48 CFR 970.5232-8 - Integrated accounting.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Integrated accounting. 970... for Management and Operating Contracts 970.5232-8 Integrated accounting. As prescribed in 970.3270(b)(2), insert the following clause: Integrated Accounting (DEC 2000) Integrated accounting procedures...

  11. Impairments in Skin Integrity.

    PubMed

    Murphree, Rose W

    2017-09-01

    Altered skin integrity increases the chance of infection, impaired mobility, and decreased function and may result in the loss of limb or, sometimes, life. Skin is affected by both intrinsic and extrinsic factors. Intrinsic factors can include altered nutritional status, vascular disease issues, and diabetes. Extrinsic factors include falls, accidents, pressure, immobility, and surgical procedures. Ensuring skin integrity in the elderly requires a team approach and includes the individual, caregivers, and clinicians. The twenty-first century clinician has several online, evidence-based tools to assist with optimal treatment plans. Understanding best practices in addressing skin integrity issues can promote positive outcomes with the elderly. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Project INTEGRATE - a common methodological approach to understand integrated health care in Europe.

    PubMed

    Cash-Gibson, Lucinda; Rosenmoller, Magdalene

    2014-10-01

    The use of case studies in health services research has proven to be an excellent methodology for gaining in-depth understanding of the organisation and delivery of health care. This is particularly relevant when looking at the complexity of integrated healthcare programmes, where multifaceted interactions occur at the different levels of care and often without a clear link between the interventions (new and/or existing) and their impact on outcomes (in terms of patients health, both patient and professional satisfaction and cost-effectiveness). Still, integrated care is seen as a core strategy in the sustainability of health and care provision in most societies in Europe and beyond. More specifically, at present, there is neither clear evidence on transferable factors of integrated care success nor a method for determining how to establish these specific success factors. The drawback of case methodology in this case, however, is that the in-depth results or lessons generated are usually highly context-specific and thus brings the challenge of transferability of findings to other settings, as different health care systems and different indications are often not comparable. Project INTEGRATE, a European Commission-funded project, has been designed to overcome these problems; it looks into four chronic conditions in different European settings, under a common methodology framework (taking a mixed-methods approach) to try to overcome the issue of context specificity and limited transferability. The common methodological framework described in this paper seeks to bring together the different case study findings in a way that key lessons may be derived and transferred between countries, contexts and patient-groups, where integrated care is delivered in order to provide insight into generalisability and build on existing evidence in this field. To compare the different integrated care experiences, a mixed-methods approach has been adopted with the creation of a common

  13. Assuring structural integrity in Army systems

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The object of this study was to recommend possible improvements in the manner in which structural integrity of Army systems is assured. The elements of a structural integrity program are described, and relevant practices used in various industries and government organizations are reviewed. Some case histories of Army weapon systems are examined. The mandatory imposition of a structural integrity program patterned after the Air Force Aircraft Structural Integrity Program is recommended and the benefits of such an action are identified.

  14. V-band integrated quadriphase modulator

    NASA Technical Reports Server (NTRS)

    Grote, A.; Chang, K.

    1983-01-01

    A V-band integrated circuit quadriphase shift keyed modulator/exciter for space communications systems was developed. Intersatellite communications systems require direct modulation at 60 GHz to enhance signal processing capability. For most systems, particularly space applications, small and lightweight components are essential to alleviate severe system design constraints. Thus to achieve wideband, high data rate systems, direct modulation techniques at millimeter waves using solid state integrated circuit technology are an integral part of the overall technology developments.

  15. HHV-6A/B Integration and the Pathogenesis Associated with the Reactivation of Chromosomally Integrated HHV-6A/B.

    PubMed

    Collin, Vanessa; Flamand, Louis

    2017-06-26

    Unlike other human herpesviruses, human herpesvirus 6A and 6B (HHV-6A/B) infection can lead to integration of the viral genome in human chromosomes. When integration occurs in germinal cells, the integrated HHV-6A/B genome can be transmitted to 50% of descendants. Such individuals, carrying one copy of the HHV-6A/B genome in every cell, are referred to as having inherited chromosomally-integrated HHV-6A/B (iciHHV-6) and represent approximately 1% of the world's population. Interestingly, HHV-6A/B integrate their genomes in a specific region of the chromosomes known as telomeres. Telomeres are located at chromosomes' ends and play essential roles in chromosomal stability and the long-term proliferative potential of cells. Considering that the integrated HHV-6A/B genome is mostly intact without any gross rearrangements or deletions, integration is likely used for viral maintenance into host cells. Knowing the roles played by telomeres in cellular homeostasis, viral integration in such structure is not likely to be without consequences. At present, the mechanisms and factors involved in HHV-6A/B integration remain poorly defined. In this review, we detail the potential biological and medical impacts of HHV-6A/B integration as well as the possible chromosomal integration and viral excision processes.

  16. European integration in crisis? Of supranational integration, hegemonic projects and domestic politics

    PubMed Central

    Bulmer, Simon; Joseph, Jonathan

    2015-01-01

    The European Union is facing multiple challenges. Departing from mainstream theory, this article adopts a fresh approach to understanding integration. It does so by taking two theoretical steps. The first introduces the structure–agency debate in order to make explicit the relationship between macro-structures, the institutional arrangements at European Union level and agency. The second proposes that the state of integration should be understood as the outcome of contestation between competing hegemonic projects that derive from underlying social processes and that find their primary expression in domestic politics. These two steps facilitate an analysis of the key areas of contestation in the contemporary European Union, illustrated by an exploration of the current crisis in the European Union, and open up the development of an alternative, critical, theory of integration. PMID:29708125

  17. Flip-chip integration of tilted VCSELs onto a silicon photonic integrated circuit.

    PubMed

    Lu, Huihui; Lee, Jun Su; Zhao, Yan; Scarcella, Carmelo; Cardile, Paolo; Daly, Aidan; Ortsiefer, Markus; Carroll, Lee; O'Brien, Peter

    2016-07-25

    In this article we describe a cost-effective approach for hybrid laser integration, in which vertical cavity surface emitting lasers (VCSELs) are passively-aligned and flip-chip bonded to a Si photonic integrated circuit (PIC), with a tilt-angle optimized for optical-insertion into standard grating-couplers. A tilt-angle of 10° is achieved by controlling the reflow of the solder ball deposition used for the electrical-contacting and mechanical-bonding of the VCSEL to the PIC. After flip-chip integration, the VCSEL-to-PIC insertion loss is -11.8 dB, indicating an excess coupling penalty of -5.9 dB, compared to Fibre-to-PIC coupling. Finite difference time domain simulations indicate that the penalty arises from the relatively poor match between the VCSEL mode and the grating-coupler.

  18. Walker Ranch 3D seismic images

    DOE Data Explorer

    Robert J. Mellors

    2016-03-01

    Amplitude images (both vertical and depth slices) extracted from 3D seismic reflection survey over area of Walker Ranch area (adjacent to Raft River). Crossline spacing of 660 feet and inline of 165 feet using a Vibroseis source. Processing included depth migration. Micro-earthquake hypocenters on images. Stratigraphic information and nearby well tracks added to images. Images are embedded in a Microsoft Word document with additional information. Exact location and depth restricted for proprietary reasons. Data collection and processing funded by Agua Caliente. Original data remains property of Agua Caliente.

  19. Highly integrated optical phased arrays: photonic integrated circuits for optical beam shaping and beam steering

    NASA Astrophysics Data System (ADS)

    Heck, Martijn J. R.

    2017-01-01

    Technologies for efficient generation and fast scanning of narrow free-space laser beams find major applications in three-dimensional (3D) imaging and mapping, like Lidar for remote sensing and navigation, and secure free-space optical communications. The ultimate goal for such a system is to reduce its size, weight, and power consumption, so that it can be mounted on, e.g. drones and autonomous cars. Moreover, beam scanning should ideally be done at video frame rates, something that is beyond the capabilities of current opto-mechanical systems. Photonic integrated circuit (PIC) technology holds the promise of achieving low-cost, compact, robust and energy-efficient complex optical systems. PICs integrate, for example, lasers, modulators, detectors, and filters on a single piece of semiconductor, typically silicon or indium phosphide, much like electronic integrated circuits. This technology is maturing fast, driven by high-bandwidth communications applications, and mature fabrication facilities. State-of-the-art commercial PICs integrate hundreds of elements, and the integration of thousands of elements has been shown in the laboratory. Over the last few years, there has been a considerable research effort to integrate beam steering systems on a PIC, and various beam steering demonstrators based on optical phased arrays have been realized. Arrays of up to thousands of coherent emitters, including their phase and amplitude control, have been integrated, and various applications have been explored. In this review paper, I will present an overview of the state of the art of this technology and its opportunities, illustrated by recent breakthroughs.

  20. Integrated Pest Management (IPM)

    Science.gov Websites

    National Pesticide Information Center 1.800.858.7378 npic@ace.orst.edu We're open from 8:00AM to 12 Plants Pest Control Identify Your Pest Learn About Your Pest Control Your Pest Integrated Pest Management Home Page Pest Control Integrated Pest Management (IPM) Related Topics: Using Pesticides Around Pets

  1. NASA Integrated Space Communications Network

    NASA Technical Reports Server (NTRS)

    Tai, Wallace; Wright, Nate; Prior, Mike; Bhasin, Kul

    2012-01-01

    The NASA Integrated Network for Space Communications and Navigation (SCaN) has been in the definition phase since 2010. It is intended to integrate NASA s three existing network elements, i.e., the Space Network, Near Earth Network, and Deep Space Network, into a single network. In addition to the technical merits, the primary purpose of the Integrated Network is to achieve a level of operating cost efficiency significantly higher than it is today. Salient features of the Integrated Network include (a) a central system element that performs service management functions and user mission interfaces for service requests; (b) a set of common service execution equipment deployed at the all stations that provides return, forward, and radiometric data processing and delivery capabilities; (c) the network monitor and control operations for the entire integrated network are conducted remotely and centrally at a prime-shift site and rotating among three sites globally (a follow-the-sun approach); (d) the common network monitor and control software deployed at all three network elements that supports the follow-the-sun operations.

  2. Evaluating Feynman integrals by the hypergeometry

    NASA Astrophysics Data System (ADS)

    Feng, Tai-Fu; Chang, Chao-Hsi; Chen, Jian-Bin; Gu, Zhi-Hua; Zhang, Hai-Bin

    2018-02-01

    The hypergeometric function method naturally provides the analytic expressions of scalar integrals from concerned Feynman diagrams in some connected regions of independent kinematic variables, also presents the systems of homogeneous linear partial differential equations satisfied by the corresponding scalar integrals. Taking examples of the one-loop B0 and massless C0 functions, as well as the scalar integrals of two-loop vacuum and sunset diagrams, we verify our expressions coinciding with the well-known results of literatures. Based on the multiple hypergeometric functions of independent kinematic variables, the systems of homogeneous linear partial differential equations satisfied by the mentioned scalar integrals are established. Using the calculus of variations, one recognizes the system of linear partial differential equations as stationary conditions of a functional under some given restrictions, which is the cornerstone to perform the continuation of the scalar integrals to whole kinematic domains numerically with the finite element methods. In principle this method can be used to evaluate the scalar integrals of any Feynman diagrams.

  3. A Physician's Perspective On Vertical Integration.

    PubMed

    Berenson, Robert A

    2017-09-01

    Vertical integration has been a central feature of health care delivery system change for more than two decades. Recent studies have demonstrated that vertically integrated health care systems raise prices and costs without observable improvements in quality, despite many theoretical reasons why cost control and improved quality might occur. Less well studied is how physicians view their newfound partnerships with hospitals. In this article I review literature findings and other observations on five aspects of vertical integration that affect physicians in their professional and personal lives: patients' access to physicians, physician compensation, autonomy versus system support, medical professionalism and culture, and lifestyle. I conclude that the movement toward physicians' alignment with and employment in vertically integrated systems seems inexorable but that policy should not promote such integration either intentionally or inadvertently. Instead, policy should address the flaws in current payment approaches that reward high prices and excessive service use-outcomes that vertical integration currently produces. Project HOPE—The People-to-People Health Foundation, Inc.

  4. Barriers and facilitators to integrating care: experiences from the English Integrated Care Pilots

    PubMed Central

    Ling, Tom; Brereton, Laura; Conklin, Annalijn; Newbould, Jennifer; Roland, Martin

    2012-01-01

    Background: In 2008, the English Department of Health appointed 16 ‘Integrated Care Pilots’ which used a range of approaches to provide better integrated care. We report qualitative analyses from a three-year multi-method evaluation to identify barriers and facilitators to successful integration of care. Theory and methods: Data were analysed from transcripts of 213 in-depth staff interviews, and from semi-structured questionnaires (the ‘Living Document’) completed by staff in pilot sites at six points over a two-year period. Emerging findings were therefore built from ‘bottom up’ and grounded in the data. However, we were then interested in how these findings compared and contrasted with more generic analyses. Therefore after our analyses were complete we then systematically compared and contrasted the findings with the analysis of barriers and facilitators to quality improvement identified in a systematic review by Kaplan et al. (2010) and the analysis of more micro-level shapers of behaviour found in Normalisation Process Theory (May et al. 2007). Neither of these approaches claims to be full blown theories but both claim to provide mid-range theoretical arguments which may be used to structure existing data and which can be undercut or reinforced by new data. Results and discussion: Many barriers and facilitators to integrating care are those of any large-scale organisational change. These include issues relating to leadership, organisational culture, information technology, physician involvement, and availability of resources. However, activities which appear particularly important for delivering integrated care include personal relationships between leaders in different organisations, the scale of planned activities, governance and finance arrangements, support for staff in new roles, and organisational and staff stability. We illustrate our analyses with a ‘routemap’ which identifies questions that providers may wish to consider when planning

  5. Boolean integral calculus for digital systems

    NASA Technical Reports Server (NTRS)

    Tucker, J. H.; Tapia, M. A.; Bennett, A. W.

    1985-01-01

    The concept of Boolean integration is introduced and developed. When the changes in a desired function are specified in terms of changes in its arguments, then ways of 'integrating' (i.e., realizing) the function, if it exists, are presented. Boolean integral calculus has applications in design of logic circuits.

  6. 40 CFR 146.8 - Mechanical integrity.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Mechanical integrity. 146.8 Section...) UNDERGROUND INJECTION CONTROL PROGRAM: CRITERIA AND STANDARDS General Provisions § 146.8 Mechanical integrity. (a) An injection well has mechanical integrity if: (1) There is no significant leak in the casing...

  7. Research on Integrated Mapping——A Case Study of Integrated Land Use with Swamp Mapping

    NASA Astrophysics Data System (ADS)

    Zhang, S.; Yan, F.; Chang, L.

    2015-12-01

    Unified real estate registration system shows the attention, determination and effort to of CPC Central Committee and State Council on real estate registration in China. However, under current situation, China's real estate registration work made less progress. One of the reasons is that it's hard to express the property right of real estate on one map under the multi-sector management system. Under current multi-sector management system in China, different departments usually just survey and mapping the land type under its jurisdiction. For example, wetland investigation only mapping all kinds of wetland resources but not mapping other resource types. As a result, it cause he problem of coincidence or leak in integration of different results from different departments. As resources of the earth's surface, the total area of forest, grassland, wetland and so on should be equal to the total area of the earth's surface area. However, under the current system, the area of all kinds of resources is not equal to the sum of the earth's surface. Therefore, it is of great importance to express all the resources on one map. On one hand, this is conducive to find out the real area and distribution of resources and avoid the problem of coincidence or leak in integration; On the other hand, it is helpful to study the dynamic change of different resources. Therefore, we first proposed the "integrated mapping" as a solution, and take integrated land use with swamp mapping in Northeast China as an example to investigate the feasibility and difficulty. Study showed that: integrated land use with swamp mapping can be achieved through combining land use survey standards with swamps survey standards and "second mapping" program. Based on the experience of integrated land use with swamp mapping, we point out its reference function on integrated mapping and unified real estate registration system. We concluded that: (1) Comprehending and integrating different survey standard of

  8. Integrative Medicine in Preventive Medicine Education

    PubMed Central

    Jani, Asim A.; Trask, Jennifer; Ali, Ather

    2016-01-01

    During 2012, the USDHHS’s Health Resources and Services Administration funded 12 accredited preventive medicine residencies to incorporate an evidence-based integrative medicine curriculum into their training programs. It also funded a national coordinating center at the American College of Preventive Medicine, known as the Integrative Medicine in Preventive Medicine Education (IMPriME) Center, to provide technical assistance to the 12 grantees. To help with this task, the IMPriME Center established a multidisciplinary steering committee, versed in integrative medicine, whose primary aim was to develop integrative medicine core competencies for incorporation into preventive medicine graduate medical education training. The competency development process was informed by central integrative medicine definitions and principles, preventive medicine’s dual role in clinical and population-based prevention, and the burgeoning evidence base of integrative medicine. The steering committee considered an interdisciplinary integrative medicine contextual framework guided by several themes related to workforce development and population health. A list of nine competencies, mapped to the six general domains of competence approved by the Accreditation Council of Graduate Medical Education, was operationalized through an iterative exercise with the 12 grantees in a process that included mapping each site’s competency and curriculum products to the core competencies. The competencies, along with central curricular components informed by grantees’ work presented elsewhere in this supplement, are outlined as a roadmap for residency programs aiming to incorporate integrative medicine content into their curricula. This set of competencies adds to the larger efforts of the IMPriME initiative to facilitate and enhance further curriculum development and implementation by not only the current grantees but other stakeholders in graduate medical education around integrative medicine

  9. Microblogging for Class: An Analysis of Affective, Cognitive, Personal Integrative, and Social Integrative Gratifications

    ERIC Educational Resources Information Center

    Gant, Camilla; Hadley, Patrick D.

    2014-01-01

    This study shows that undergraduate students can gratify cognitive, affective, social integrative, and personal integrative needs microblogging via a learning management system discussion tool. Moreover, the researchers find that microblogging about news regarding mass media events and issues via Blackboard heightened engagement, expanded…

  10. Combustion Integration Rack (CIR) Testing

    NASA Image and Video Library

    2015-02-18

    Fluids and Combustion Facility (FCF), Combustion Integration Rack (CIR) during testing in the Structural Dynamics Laboratory (SDL). The Fluids and Combustion Facility (FCF) is a set of two International Space Station (ISS) research facilities designed to support physical and biological experiments in support of technology development and validation in space. The FCF consists of two modular, reconfigurable racks called the Combustion Integration Rack (CIR) and the Fluids Integration Rack (FIR). The CIR and FIR were developed at NASAʼs Glenn Research Center.

  11. Four Ways to Skin a Definite Integral

    ERIC Educational Resources Information Center

    Dence, Thomas; Dence, Joseph

    2010-01-01

    The integral of 1/(1 + x[superscript 2]) is standard in elementary calculus, but the related integral 1/(1 + x[superscript 4]) rarely appears. In this article we examine the latter integral, computing its value by four different methods; several that involve standard elementary calculus techniques, and several involving complex integration.

  12. Cockpit avionics integration and automation

    NASA Technical Reports Server (NTRS)

    Pischke, Keith M.

    1990-01-01

    Information on cockpit avionics integration and automation is given in viewgraph form, with a number of photographs. The benefits of cockpit integration are listed. The MD-11 flight guidance/flight deck system is illustrated.

  13. Hydrochemistry of waters from five cenotes and evaluation of their suitability for drinking-water supplies, northeastern Yucatan, Mexico

    NASA Astrophysics Data System (ADS)

    Alcocer, Javier; Lugo, Alfonso; Marín, Luis E.; Escobar, Elva

    Waters from five cenotes that are currently being used for aquatic recreational activities and that lie along the Cancun-Tulum touristic corridor, Mexico, were evaluated hydrochemically to determine whether the cenotes may be considered as potential drinking-water sources. Several parameters exceed the Mexican Drinking Water Standards (MDWS), but since they do not pose a significant health threat, four of the five cenotes may be used as drinking-water sources. The common contaminants in the Yucatan Peninsula, fecal coliforms and nitrate, are in most cases below the MDWS (0-460 MPN/100ml and 0.31-1.18mg/L, respectively). Although these four cenotes meet the MDWS, a careful groundwater management policy needs to be developed to avoid contamination (fecal and nitrates) and salt-water intrusion. Résumé Les eaux de cinq cénotés, qui sont normalement utilisées pour des activités de plein air, dans la région touristique de Cancun-Tulum (Mexique), ont été soumises à analyses chimiques pour savoir si les cénotés peuvent être considérés comme des sources d'eau potable. Plusieurs paramètres dépassent les normes mexicaines en matière d'eau potable; mais comme ceux-ci ne posent pas de problème réel de santé, quatre des cinq cénotés peuvent être captés pour l'eau potable. Les contaminants habituels dans les eaux de la presqu'île du Yucatan, coliformes fécaux et concentrations élevées en nitrate, sont la plupart du temps au-dessous des normes (respectivement 0 à 460 germes/100ml et 0,31 à 1,18mg/l). Bien que ces quatre cénotés satisfassent aux normes, il est nécessaire de mettre en place des règles précises de l'utilisation de l'eau souterraine, afin d'éviter la contamination par les germes fécaux et par les nitrates, ainsi que l'intrusion marine. Resumen Se analizó hidroquímica y bacteriológicamente el agua de algunos cenotes localizados a lo largo del corredor turístico Cancun-Tulum, que actualmente se utilizan para diversas actividades

  14. [Clinical integration in the chronic patient].

    PubMed

    Carretero-Alcántara, Luis; Comes-Górriz, Natividad; Borrás-López, Agustina; Rodríguez-Balo, Alberto; Seara-Aguilar, Germán

    2014-01-01

    Castilla-La Mancha Health Service is developing the integration of care levels due to the challenge of an aging population in the region. Aging is associated with chronic diseases and an increasing number of concomitant diseases. This poses a major care challenge care, with more fragile patients and new needs. This also requires a sustainable approach: the concurrence of several chronic diseases affects the cost of care, which is especially acute in times of severe economic crisis. One of the pillars of the strategy for dealing with chronic diseases in our region is care integration, in an effort to adapt the organization to the new needs. The Balanced Scorecard or Integrated Scorecard of the integration process was introduced as it has been designed. The integration of primary and hospital care at an organizational level has already been completed, and the development of integrated care processes has also been performed in order to achieve real integration at care level. To help finance this, a prospective capitation system is gradually being implemented, achieving a convergence of per capita costs in the different health areas integrated. Nurses has a key role in this process, their skills as educators and trainers in self-care, in the role of case managers of patients with particularly complex conditions, and the role of professional liaison to improve the transition between care areas and units. Copyright © 2013 Elsevier España, S.L. All rights reserved.

  15. Integrated primary care, the collaboration imperative inter-organizational cooperation in the integrated primary care field: a theoretical framework

    PubMed Central

    Valentijn, Pim P; Bruijnzeels, Marc A; de Leeuw, Rob J; Schrijvers, Guus J.P

    2012-01-01

    Purpose Capacity problems and political pressures have led to a rapid change in the organization of primary care from mono disciplinary small business to complex inter-organizational relationships. It is assumed that inter-organizational collaboration is the driving force to achieve integrated (primary) care. Despite the importance of collaboration and integration of services in primary care, there is no unambiguous definition for both concepts. The purpose of this study is to examine and link the conceptualisation and validation of the terms inter-organizational collaboration and integrated primary care using a theoretical framework. Theory The theoretical framework is based on the complex collaboration process of negotiation among multiple stakeholder groups in primary care. Methods A literature review of health sciences and business databases, and targeted grey literature sources. Based on the literature review we operationalized the constructs of inter-organizational collaboration and integrated primary care in a theoretical framework. The framework is being validated in an explorative study of 80 primary care projects in the Netherlands. Results and conclusions Integrated primary care is considered as a multidimensional construct based on a continuum of integration, extending from segregation to integration. The synthesis of the current theories and concepts of inter-organizational collaboration is insufficient to deal with the complexity of collaborative issues in primary care. One coherent and integrated theoretical framework was found that could make the complex collaboration process in primary care transparent. This study presented theoretical framework is a first step to understand the patterns of successful collaboration and integration in primary care services. These patterns can give insights in the organization forms needed to create a good working integrated (primary) care system that fits the local needs of a population. Preliminary data of the

  16. Probabilistic data integration and computational complexity

    NASA Astrophysics Data System (ADS)

    Hansen, T. M.; Cordua, K. S.; Mosegaard, K.

    2016-12-01

    Inverse problems in Earth Sciences typically refer to the problem of inferring information about properties of the Earth from observations of geophysical data (the result of nature's solution to the `forward' problem). This problem can be formulated more generally as a problem of `integration of information'. A probabilistic formulation of data integration is in principle simple: If all information available (from e.g. geology, geophysics, remote sensing, chemistry…) can be quantified probabilistically, then different algorithms exist that allow solving the data integration problem either through an analytical description of the combined probability function, or sampling the probability function. In practice however, probabilistic based data integration may not be easy to apply successfully. This may be related to the use of sampling methods, which are known to be computationally costly. But, another source of computational complexity is related to how the individual types of information are quantified. In one case a data integration problem is demonstrated where the goal is to determine the existence of buried channels in Denmark, based on multiple sources of geo-information. Due to one type of information being too informative (and hence conflicting), this leads to a difficult sampling problems with unrealistic uncertainty. Resolving this conflict prior to data integration, leads to an easy data integration problem, with no biases. In another case it is demonstrated how imperfections in the description of the geophysical forward model (related to solving the wave-equation) can lead to a difficult data integration problem, with severe bias in the results. If the modeling error is accounted for, the data integration problems becomes relatively easy, with no apparent biases. Both examples demonstrate that biased information can have a dramatic effect on the computational efficiency solving a data integration problem and lead to biased results, and under

  17. Integrated Healthcare Delivery: A Qualitative Research Approach to Identifying and Harmonizing Perspectives of Integrated Neglected Tropical Disease Programs

    PubMed Central

    Jacobson, Julie; Mosher, Aryc W.; Walson, Judd L.

    2016-01-01

    Background While some evidence supports the beneficial effects of integrating neglected tropical disease (NTD) programs to optimize coverage and reduce costs, there is minimal information regarding when or how to effectively operationalize program integration. The lack of systematic analyses of integration experiences and of integration processes may act as an impediment to achieving more effective NTD programming. We aimed to learn about the experiences of NTD stakeholders and their perceptions of integration. Methodology We evaluated differences in the definitions, roles, perceived effectiveness, and implementation experiences of integrated NTD programs among a variety of NTD stakeholder groups, including multilateral organizations, funding partners, implementation partners, national Ministry of Health (MOH) teams, district MOH teams, volunteer rural health workers, and community members participating in NTD campaigns. Semi-structured key informant interviews were conducted. Coding of themes involved a mix of applying in-vivo open coding and a priori thematic coding from a start list. Findings In total, 41 interviews were conducted. Salient themes varied by stakeholder, however dominant themes on integration included: significant variations in definitions, differential effectiveness of specific integrated NTD activities, community member perceptions of NTD programs, the influence of funders, perceived facilitators, perceived barriers, and the effects of integration on health system strength. In general, stakeholder groups provided unique perspectives, rather than contrarian points of view, on the same topics. The stakeholders identified more advantages to integration than disadvantages, however there are a number of both unique facilitators and challenges to integration from the perspective of each stakeholder group. Conclusions Qualitative data suggest several structural, process, and technical opportunities that could be addressed to promote more effective and

  18. An Overview of Integration and Test of the James Webb Space Telescope Integrated Science Instrument Module

    NASA Technical Reports Server (NTRS)

    Drury, Michael; Becker, Neil; Bos, Brent; Davila, Pamela; Frey, Bradley; Hylan, Jason; Marsh, James; McGuffey, Douglas; Novak, Maria; Ohl, Raymond; hide

    2007-01-01

    The James Webb Space Telescope (JWST) is a 6.6m diameter, segmented, deployable telescope for cryogenic IR space astronomy (approx.40K). The JWST Observatory architecture includes the Optical Telescope Element (OTE) and the Integrated Science Instrument Module (ISIM) element that contains four science instruments (SI) including a Guider. The SIs and Guider are mounted to a composite metering structure with outer dimensions of 2.1x2.2x1.9m. The SI and Guider units are integrated to the ISIM structure and optically tested at NASA/Goddard Space Flight Center as an instrument suite using a high-fidelity, cryogenic JWST telescope simulator that features a 1.5m diameter powered mirror. The SIs are integrated and aligned to the structure under ambient, clean room conditions. SI performance, including focus, pupil shear and wavefront error, is evaluated at the operating temperature. We present an overview of the ISIM integration within the context of Observatory-level construction. We describe the integration and verification plan for the ISIM element, including an overview of our incremental verification approach, ambient mechanical integration and test plans and optical alignment and cryogenic test plans. We describe key ground support equipment and facilities.

  19. Safety in Schools: An Integral Approach

    ERIC Educational Resources Information Center

    Gairin, Joaquin; Castro, Diego

    2011-01-01

    The present paper summarizes a research project into integral safety in schools. The aims of this particular research are, firstly, to evaluate the degree of integral safety in schools, secondly, to propose means for improving prevention and integral safety systems and thirdly, to identify the characteristics of safety culture. The field work was…

  20. Integrated Design Tools Reduce Risk, Cost

    NASA Technical Reports Server (NTRS)

    2012-01-01

    Thanks in part to a SBIR award with Langley Research Center, Phoenix Integration Inc., based in Wayne, Pennsylvania, modified and advanced software for process integration and design automation. For NASA, the tool has resulted in lower project costs and reductions in design time; clients of Phoenix Integration are experiencing the same rewards.

  1. Teaching Integrative Thought: Techniques and Data.

    ERIC Educational Resources Information Center

    Malloy, Thomas E.

    Focusing on techniques for teaching students to integrate diverse ideas at a deep level of cognitive processing, a study evaluated an idea integration package for teaching writing in the college classroom. Subjects, 29 college students from an introductory psychology class at a Utah university, were divided into two groups. The integration group…

  2. Modeling integrated biomass gasification business concepts

    Treesearch

    Peter J. Ince; Ted Bilek; Mark A. Dietenberger

    2011-01-01

    Biomass gasification is an approach to producing energy and/or biofuels that could be integrated into existing forest product production facilities, particularly at pulp mills. Existing process heat and power loads tend to favor integration at existing pulp mills. This paper describes a generic modeling system for evaluating integrated biomass gasification business...

  3. 46 CFR 119.435 - Integral fuel tanks.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 4 2012-10-01 2012-10-01 false Integral fuel tanks. 119.435 Section 119.435 Shipping... Machinery Requirements § 119.435 Integral fuel tanks. (a) Diesel fuel tanks may not be built integral with... for certification of a vessel, integral fuel tanks must withstand a hydrostatic pressure test of 35 k...

  4. 46 CFR 119.435 - Integral fuel tanks.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 4 2013-10-01 2013-10-01 false Integral fuel tanks. 119.435 Section 119.435 Shipping... Machinery Requirements § 119.435 Integral fuel tanks. (a) Diesel fuel tanks may not be built integral with... for certification of a vessel, integral fuel tanks must withstand a hydrostatic pressure test of 35 k...

  5. Dendritic integration: 60 years of progress.

    PubMed

    Stuart, Greg J; Spruston, Nelson

    2015-12-01

    Understanding how individual neurons integrate the thousands of synaptic inputs they receive is critical to understanding how the brain works. Modeling studies in silico and experimental work in vitro, dating back more than half a century, have revealed that neurons can perform a variety of different passive and active forms of synaptic integration on their inputs. But how are synaptic inputs integrated in the intact brain? With the development of new techniques, this question has recently received substantial attention, with new findings suggesting that many of the forms of synaptic integration observed in vitro also occur in vivo, including in awake animals. Here we review six decades of progress, which collectively highlights the complex ways that single neurons integrate their inputs, emphasizing the critical role of dendrites in information processing in the brain.

  6. Enabling Agile Testing through Continuous Integration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stolberg, Sean E.

    2009-08-24

    A Continuous Integration system is often considered one of the key elements involved in supporting an agile software development and testing environment. As a traditional software tester transitioning to an agile development environment it became clear to me that I would need to put this essential infrastructure in place and promote improved development practices in order to make the transition to agile testing possible. This experience report discusses a continuous integration implementation I lead last year. The initial motivations for implementing continuous integration are discussed and a pre and post-assessment using Martin Fowler's "Practices of Continuous Integration" is provided alongmore » with the technical specifics of the implementation. Finally, I’ll wrap up with a retrospective of my experiences implementing and promoting continuous integration within the context of agile testing.« less

  7. Integration: the firm and the health care sector.

    PubMed

    Laugesen, Miriam J; France, George

    2014-07-01

    Integration in health care is a key goal of health reform in United States and England. Yet past efforts in the 1990s to better integrate the delivery system were of limited success. Building on work by Bevan and Janus on delivery integration, this article explores integration through the lens of economic theories of integration. Firms generally integrate to increase efficiency through economies of scale, to improve their market power, and resolve the transaction costs involved with multiple external suppliers. Using the United States and England as laboratories, we apply concepts of economic integration to understand why integration does or does not occur in health care, and whether expectations of integrating different kinds of providers (hospital, primary care) and health and social services are realistic. Current enthusiasm for a more integrated health care system expands the scope of integration to include social services in England, but retains the focus on health care in the United States. We find mixed applicability of economic theories of integration. Economies of scale have not played a significant role in stimulating integration in both countries. Managerial incentives for monopoly or oligopoly may be more compelling in the United States, since hospitals seek higher prices and more leverage over payers. In both countries the concept of transaction costs could explain the success of new payment and budgeting methods, since health care integration ultimately requires resolving transaction costs across different delivery organizations.

  8. Making Integration Work: A Teacher's Perspective. A Guide to Integrating Handicapped and Nonhandicapped Preschool Children. Appendix D.

    ERIC Educational Resources Information Center

    Price, Marilyn; Weinberg, Nessa

    The manual is intended to help teachers who are integrating handicapped children into preschool programs. It opens with a description of the Albuquerque Special Preschool, a program in which handicapped children were integrated in successively less restrictive environments. The raltionale for integration is presented in terms of research and of…

  9. Respect for persons, respect for integrity: remarks for the conceptualization of integrity in social ethics.

    PubMed

    Fjellstrom, Roger

    2005-01-01

    Even though respect for integrity is hailed in several authoritative legal and ethical documents, and is typically presented as a complement to respect for autonomy, it is largely neglected in many leading works in ethics. Is such neglect warranted, or does it express a prejudice? This article argues that the latter is the case, and that this is due to misplaced conceptual concerns. It offers some proposals as regards the conceptualization of integrity in social ethics in general and in biomedical ethics in particular. Five main directions of interpretation of "integrity" are discerned and shown to be relevant for different areas of biomedical ethics. The defense of respect for integrity is served by a softening of principlism and by greater attention to context among the initial critics of this principle.

  10. Integrated, Continuous Emulsion Creamer.

    PubMed

    Cochrane, Wesley G; Hackler, Amber L; Cavett, Valerie J; Price, Alexander K; Paegel, Brian M

    2017-12-19

    Automated and reproducible sample handling is a key requirement for high-throughput compound screening and currently demands heavy reliance on expensive robotics in screening centers. Integrated droplet microfluidic screening processors are poised to replace robotic automation by miniaturizing biochemical reactions to the droplet scale. These processors must generate, incubate, and sort droplets for continuous droplet screening, passively handling millions of droplets with complete uniformity, especially during the key step of sample incubation. Here, we disclose an integrated microfluidic emulsion creamer that packs ("creams") assay droplets by draining away excess oil through microfabricated drain channels. The drained oil coflows with creamed emulsion and then reintroduces the oil to disperse the droplets at the circuit terminus for analysis. Creamed emulsion assay incubation time dispersion was 1.7%, 3-fold less than other reported incubators. The integrated, continuous emulsion creamer (ICEcreamer) was used to miniaturize and optimize measurements of various enzymatic activities (phosphodiesterase, kinase, bacterial translation) under multiple- and single-turnover conditions. Combining the ICEcreamer with current integrated microfluidic DNA-encoded library bead processors eliminates potentially cumbersome instrumentation engineering challenges and is compatible with assays of diverse target class activities commonly investigated in drug discovery.

  11. Task Integration Facilitates Multitasking.

    PubMed

    de Oliveira, Rita F; Raab, Markus; Hegele, Mathias; Schorer, Jörg

    2017-01-01

    The aim of this study was to investigate multi-task integration in a continuous tracking task. We were particularly interested in how manipulating task structure in a dual-task situation affects learning of a constant segment embedded in a pursuit-tracking task. Importantly, we examined if dual-task effects could be attributed to task integration by varying the structural similarity and difficulty of the primary and secondary tasks. In Experiment 1 participants performed a pursuit tracking task while counting high-pitched tones and ignoring low-pitched tones. The tones were either presented randomly or structurally 250 ms before each tracking turn. Experiment 2 increased the motor load of the secondary tasks by asking participants to tap their feet to the tones. Experiment 3 further increased motor load of the primary task by increasing its speed and having participants tracking with their non-dominant hand. The results show that dual-task interference can be moderated by secondary task conditions that match the structure of the primary task. Therefore our results support proposals of task integration in continuous tracking paradigms. We conclude that multi-tasking is not always detrimental for motor learning but can be facilitated through task-integration.

  12. Constituting children's bodily integrity.

    PubMed

    Hill, B Jessie

    2015-04-01

    Children have a constitutional right to bodily integrity. Courts do not hesitate to vindicate that right when children are abused by state actors. Moreover, in at least some cases, a child's right to bodily integrity applies within the family, giving the child the right to avoid unwanted physical intrusions regardless of the parents' wishes. Nonetheless, the scope of this right vis-à-vis the parents is unclear; the extent to which it applies beyond the narrow context of abortion and contraception has been almost entirely unexplored and untheorized. This Article is the first in the legal literature to analyze the constitutional right of minors to bodily integrity within the family by spanning traditionally disparate doctrinal categories such as abortion rights; corporal punishment; medical decisionmaking; and nontherapeutic physical interventions such as tattooing, piercing, and circumcision. However, the constitutional right of minors to bodily integrity raises complex philosophical questions concerning the proper relationship between family and state, as well as difficult doctrinal and theoretical issues concerning the ever-murky idea of state action. This Article canvasses those issues with the ultimate goal of delineating a constitutional right of bodily security and autonomy for children.

  13. Morphological evolution through integration: a quantitative study of cranial integration in Homo, Pan, Gorilla and Pongo.

    PubMed

    Singh, Nandini; Harvati, Katerina; Hublin, Jean-Jacques; Klingenberg, Christian P

    2012-01-01

    Morphological integration refers to coordinated variation among traits that are closely related in development and/or function. Patterns of integration can offer important insight into the structural relationship between phenotypic units, providing a framework to address questions about phenotypic evolvability and constraints. Integrative features of the primate cranium have recently become a popular subject of study. However, an important question that still remains under-investigated is: what is the pattern of cranial shape integration among closely related hominoids? To address this question, we conducted a Procrustes-based geometric morphometrics study to quantify and analyze shape covariation patterns between different cranial regions in Homo, Pan, Gorilla and Pongo. A total of fifty-six 3D landmarks were collected on 407 adult individuals. We then sub-divided the landmarks corresponding to cranial units as outlined in the 'functional matrix hypothesis.' Sub-dividing the cranium in this manner allowed us to explore patterns of covariation between the face, basicranium and cranial vault, using the two-block partial least squares approach. Our results suggest that integrated shape changes in the hominoid cranium are complex, but that the overall pattern of integration is similar among human and non-human apes. Thus, despite having very distinct morphologies the way in which the face, basicranium and cranial vault covary is shared among these taxa. These results imply that the pattern of cranial integration among hominoids is conserved. Copyright © 2011 Elsevier Ltd. All rights reserved.

  14. INTEGRAL Observations of GW170104

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Savchenko, V.; Ferrigno, C.; Bozzo, E.

    2017-09-10

    We used data from the International Gamma-Ray Astrophysics Laboratory ( INTEGRAL ) to set upper limits on the γ -ray and hard X-ray prompt emission associated with the gravitational-wave event GW170104, discovered by the Laser Interferometer Gravitational-wave Observatory (LIGO)/Virgo collaboration. The unique omnidirectional viewing capability of the instruments on board INTEGRAL allowed us to examine the full 90% confidence level localization region of the LIGO trigger. Depending on the particular spectral model assumed and the specific position within this region, the upper limits inferred from the INTEGRAL observations range from F {sub γ} = 1.9 × 10{sup −7} erg cm{supmore » −2} to F {sub γ} = 10{sup −6} erg cm{sup −2} (75 keV–2 MeV energy range). This translates into a ratio between the prompt energy released in γ -rays along the direction to the observer and the gravitational-wave energy of E {sub γ} / E {sub GW} < 2.6 × 10{sup −5}. Using the INTEGRAL results, we cannot confirm the γ -ray proposed counterpart to GW170104 by the Astro—Rivelatore Gamma a Immagini Leggero (AGILE) team with the mini-Calorimeter (MCAL) instrument. The reported flux of the AGILE/MCAL event, E2, is not compatible with the INTEGRAL upper limits within most of the 90% LIGO localization region. There is only a relatively limited portion of the sky where the sensitivity of the INTEGRAL instruments was not optimal and the lowest-allowed fluence estimated for E2 would still be compatible with the INTEGRAL results. This region was also observed independently by Fermi /Gamma-ray Burst Monitor and AstroSAT, from which, as far as we are aware, there are no reports of any significant detection of a prompt high-energy event.« less

  15. Construction of integrated case environments.

    PubMed

    Losavio, Francisca; Matteo, Alfredo; Pérez, María

    2003-01-01

    The main goal of Computer-Aided Software Engineering (CASE) technology is to improve the entire software system development process. The CASE approach is not merely a technology; it involves a fundamental change in the process of software development. The tendency of the CASE approach, technically speaking, is the integration of tools that assist in the application of specific methods. In this sense, the environment architecture, which includes the platform and the system's hardware and software, constitutes the base of the CASE environment. The problem of tools integration has been proposed for two decades. Current integration efforts emphasize the interoperability of tools, especially in distributed environments. In this work we use the Brown approach. The environment resulting from the application of this model is called a federative environment, focusing on the fact that this architecture pays special attention to the connections among the components of the environment. This approach is now being used in component-based design. This paper describes a concrete experience in civil engineering and architecture fields, for the construction of an integrated CASE environment. A generic architectural framework based on an intermediary architectural pattern is applied to achieve the integration of the different tools. This intermediary represents the control perspective of the PAC (Presentation-Abstraction-Control) style, which has been implemented as a Mediator pattern and it has been used in the interactive systems domain. In addition, a process is given to construct the integrated CASE.

  16. Integrating Weather in TMC Operations

    DOT National Transportation Integrated Search

    2008-06-30

    This report presents the results of a study of the integration of weather information into Transportation Management Centers (TMCs). Based on an earlier report that examined the nature and extent of weather integration experience across the country a...

  17. Integral presentations of Catalan numbers

    NASA Astrophysics Data System (ADS)

    Dana-Picard, Thierry

    2010-01-01

    We compute in three different ways the same definite parametric integral. By-products are the derivation of a combinatorial identity and two integral presentations of Catalan numbers. One of them leads to a presentation using the γ function.

  18. Integral Presentations of Catalan Numbers

    ERIC Educational Resources Information Center

    Dana-Picard, Thierry

    2010-01-01

    We compute in three different ways the same definite parametric integral. By-products are the derivation of a combinatorial identity and two integral presentations of Catalan numbers. One of them leads to a presentation using the [gamma] function.

  19. Integration of design and inspection

    NASA Astrophysics Data System (ADS)

    Simmonds, William H.

    1990-08-01

    Developments in advanced computer integrated manufacturing technology, coupled with the emphasis on Total Quality Management, are exposing needs for new techniques to integrate all functions from design through to support of the delivered product. One critical functional area that must be integrated into design is that embracing the measurement, inspection and test activities necessary for validation of the delivered product. This area is being tackled by a collaborative project supported by the UK Government Department of Trade and Industry. The project is aimed at developing techniques for analysing validation needs and for planning validation methods. Within the project an experimental Computer Aided Validation Expert system (CAVE) is being constructed. This operates with a generalised model of the validation process and helps with all design stages: specification of product requirements; analysis of the assurance provided by a proposed design and method of manufacture; development of the inspection and test strategy; and analysis of feedback data. The kernel of the system is a knowledge base containing knowledge of the manufacturing process capabilities and of the available inspection and test facilities. The CAVE system is being integrated into a real life advanced computer integrated manufacturing facility for demonstration and evaluation.

  20. Energy Systems Integration Facility Control Room | Energy Systems

    Science.gov Websites

    Integration Facility | NREL Energy Systems Integration Facility Control Room Energy Systems Integration Facility Control Room The Energy Systems Integration Facility control room allows system engineers as the monitoring point for the facility's integrated safety and control systems. Photo of employees

  1. Energy Systems Integration News | Energy Systems Integration Facility |

    Science.gov Websites

    technologies and business models help utilities and tech companies address integrate distributed energy invaders: Disruptive technologies crowding the utility space" at the Utilities in a Time of Change and Franyutti, Vice-President, Energy Business Group, Mexichem

  2. The Integration of Study and Work-Integrated Learning Experience through the Sequential, Embedded Completion of Tertiary Qualifications

    ERIC Educational Resources Information Center

    Whannell, Patricia; Humphries, Judy; Whannell, Robert; Usher, Kim

    2015-01-01

    A number of different models have been developed to integrate both Vocational Education and Training (VET) and university study with a view to producing work-ready graduates. This paper describes one joint initiative which allows students to integrate their theoretical study and work-integrated learning (WIL) experience by supporting a sequential,…

  3. A Comprehensive Definition for Integrative Oncology.

    PubMed

    Witt, Claudia M; Balneaves, Lynda G; Cardoso, Maria J; Cohen, Lorenzo; Greenlee, Heather; Johnstone, Peter; Kücük, Ömer; Mailman, Josh; Mao, Jun J

    2017-11-01

    Integrative oncology, which is generally understood to refer to the use of a combination of complementary medicine therapies in conjunction with conventional cancer treatments, has been defined in different ways, but there is no widely accepted definition. We sought to develop and establish a consensus for a comprehensive definition of the field of integrative oncology. We used a mixed-methods approach that included a literature analysis and a consensus procedure, including an interdisciplinary expert panel and surveys, to develop a comprehensive and acceptable definition for the term "integrative oncology." The themes identified in the literature and from the expert discussion were condensed into a two-sentence definition. Survey respondents had very positive views on the draft definition, and their comments helped to shape the final version. The final definition for integrative oncology is: "Integrative oncology is a patient-centered, evidence-informed field of cancer care that utilizes mind and body practices, natural products, and/or lifestyle modifications from different traditions alongside conventional cancer treatments. Integrative oncology aims to optimize health, quality of life, and clinical outcomes across the cancer care continuum and to empower people to prevent cancer and become active participants before,during, and beyond cancer treatment." This short and comprehensive definition for the term integrative oncology will facilitate a better understanding and communication of this emerging field. This definition will also drive focused and cohesive effort to advance the field of integrative oncology. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  4. Improving pharmacy revenue integrity.

    PubMed

    Carmody, Jennifer J; Townsend, Kyle; Schwartz, Kathy

    2013-09-01

    Billings Clinic learned the following important lessons in implementing a pharmacy revenue integrity initiative: Integrate pharmacy data as fully as possible. Audit and review pharmacy data regularly to validate the data and identify key areas where education can be provided to support accuracy and compliance. Use technology to bridge gaps between pharmacy data, such as gaps in billable units and billed units. Establish data governance workflows.

  5. [Promoting Research Integrity].

    PubMed

    Suzuki, Hiromichi

    2018-01-01

     Japan Agency for Medical Research and Development (AMED) was launched in April 2015 to promote integrated medical research and development (R&D) ranging from basic research to practical applications, in order to smoothly achieve the nationwide application of research outcomes, and to establish an environment therefor. AMED consolidates budgets for R&D expenses, which had previously been allocated from different sources, such as the Ministry of Education, Culture, Sports, Science and Technology, the Ministry of Health, Labour and Welfare, and the Ministry of Economy, Trade and Industry. It provides funds strategically to universities, research institutions, etc. By promoting medical R&D, AMED aims to achieve the world's highest level of medical care/services to contribute to a society in which people live long and healthy lives. To achieve this mission, it is imperative that R&D funded by AMED is widely understood and supported. Maintaining and improving research integrity is a prerequisite to this end. AMED is taking various measures to ensure fair and appropriate R&D. It is asking researchers to participate in its responsible conduct in research (RCR) education program and to comply with its rules for managing conflicts of interest (COI). In addition, AMED also conducts a grant program to create and distribute a variety of educational materials on RCR and other matters. Further, AMED is establishing a platform that allows researchers to exchange information about research integrity, and it is undertaking additional measures, such as holding meetings and international symposia on research integrity.

  6. Perfect discretization of path integrals

    NASA Astrophysics Data System (ADS)

    Steinhaus, Sebastian

    2012-05-01

    In order to obtain a well-defined path integral one often employs discretizations. In the case of General Relativity these generically break diffeomorphism symmetry, which has severe consequences since these symmetries determine the dynamics of the corresponding system. In this article we consider the path integral of reparametrization invariant systems as a toy example and present an improvement procedure for the discretized propagator. Fixed points and convergence of the procedure are discussed. Furthermore we show that a reparametrization invariant path integral implies discretization independence and acts as a projector onto physical states.

  7. Integrated residential photovoltaic array development

    NASA Technical Reports Server (NTRS)

    Shepard, N. F., Jr.

    1981-01-01

    The design details of an optimized integrated residential photovoltaic module/array are presented. This selected design features a waterproofing and mounting scheme which was devised to simplify the installation procedures by the avoidance of complex gasketed or caulked joints, while still maintaining a high confidence that the watertight integrity of the integral roofing surface will be achieved for the design lifetime of the system. The production and installation costs for the selected module/array design are reported for a range of annual production rates as a function of the cost of solar cells.

  8. Integrative medicine for cancer treatment

    MedlinePlus

    ... page: //medlineplus.gov/ency/patientinstructions/000932.htm Integrative medicine for cancer treatment To use the sharing features on this page, ... for cancer includes surgery, chemotherapy , radiation , and biological therapy . Integrative medicine is complementary care used alongside standard care. It ...

  9. Turkish Preschool Teachers' Beliefs on Integrated Curriculum: Integration of Visual Arts with Other Activities

    ERIC Educational Resources Information Center

    Ozturk, Elif; Erden, Feyza Tantekin

    2011-01-01

    This study investigates preschool teachers' beliefs about integrated curriculum and, more specifically, their beliefs about integration of visual arts with other activities. The participants of this study consisted of 255 female preschool teachers who are employed in preschools in Ankara, Turkey. For the study, teachers were asked to complete…

  10. Let's Talk about Integration: A Study of Students' Understandings of Integration

    ERIC Educational Resources Information Center

    Laksov, Klara Bolander; McGrath, Cormac; Josephson, Anna

    2014-01-01

    Today, the knowledge concerning clinical reasoning is advanced enough to translate into curriculum interventions such as an integrated curriculum, in which science theory and clinical practice can be interwoven effectively. However, the interpretations of what integration means differ and the purpose of this study was to elicit how students…

  11. Integration Testing of Space Flight Systems

    NASA Technical Reports Server (NTRS)

    Honeycutt, Timothy; Sowards, Stephanie

    2008-01-01

    Based on the previous success' of Multi-Element Integration Testing (MEITs) for the International Space Station Program, these type of integrated tests have also been planned for the Constellation Program: MEIT (1) CEV to ISS (emulated) (2) CEV to Lunar Lander/EDS (emulated) (3) Future: Lunar Surface Systems and Mars Missions Finite Element Integration Test (FEIT) (1) CEV/CLV (2) Lunar Lander/EDS/CaL V Integrated Verification Tests (IVT) (1) Performed as a subset of the FEITs during the flight tests and then performed for every flight after Full Operational Capability (FOC) has been obtained with the flight and ground Systems.

  12. Creating environments that foster academic integrity.

    PubMed

    Tippitt, Michelle Pixley; Ard, Nell; Kline, Juanita Reese; Tilghman, Joan; Chamberlain, Barbara; Meagher, P Gail

    2009-01-01

    A number of studies related to academic dishonesty within the nursing student population have been published; however, little has been written in the nursing literature regarding academic integrity and means of promoting this value. In addition to the many short-term solutions to prevent cheating and dissuade academic misconduct that are offered, solutions that promote long-term affective changes underlying the acquisition of academic integrity are needed. This article provides a context for discussions related to academic integrity, explores issues facing faculty when dealing with this challenge, and offers short-term and long-term strategies for creating environments that foster academic integrity.

  13. Revisiting Organisational Learning in Integrated Care.

    PubMed

    Nuño-Solinís, Roberto

    2017-08-11

    Progress in health care integration is largely linked to changes in processes and ways of doing. These changes have knowledge management and learning implications. For this reason, the use of the concept of organisational learning is explored in the field of integrated care. There are very limited contributions that have connected the fields of organisational learning and care integration in a systematic way, both at the theoretical and empirical level. For this reason, hybridization of both perspectives still provides opportunities for understanding care integration initiatives from a research perspective as well as potential applications in health care management and planning.

  14. Revisiting Organisational Learning in Integrated Care

    PubMed Central

    2017-01-01

    Progress in health care integration is largely linked to changes in processes and ways of doing. These changes have knowledge management and learning implications. For this reason, the use of the concept of organisational learning is explored in the field of integrated care. There are very limited contributions that have connected the fields of organisational learning and care integration in a systematic way, both at the theoretical and empirical level. For this reason, hybridization of both perspectives still provides opportunities for understanding care integration initiatives from a research perspective as well as potential applications in health care management and planning. PMID:28970762

  15. Teacher Conceptions of Integrated STEM Education and How They Are Reflected in Integrated STEM Curriculum Writing and Classroom Implementation

    NASA Astrophysics Data System (ADS)

    Ring, Elizabeth A.

    There has been a nation-wide push for an increase in the use of integrated science, technology, engineering, and mathematics (STEM) education in the United States. With this shift in epistemological, pedagogical, and curricular content, there is a need to develop an understanding as to what integrated STEM education is, particularly among practitioners. In this dissertation, inservice science teacher conceptions of integrated STEM education were investigated to help understand what these conceptions are and how these conceptions influence curriculum writing and implementation of integrated STEM curricula in classrooms. Teacher conceptions and their influences were investigated through three separate but interrelated studies. First, K-12 inservice science teachers' conceptions of integrated STEM were investigated through the analysis of their sketched models of integrated STEM education. How these models changed throughout an intensive, three-week professional development was also explored. The goal of this first study was to identify conceptual models of integrated STEM education held by inservice science teachers and to understand how these conceptions might change over the course of a professional development. Second, photo elicitation interviews (PEIs) and curricular analysis were used to provide rich descriptions of the conceptual models of integrated STEM education held by inservice science teachers, determine what components of STEM inservice science teachers found fundamental to integrating STEM in the classroom based on their conceptions, and explore how teachers' conceptions of STEM were used in their development of integrated STEM curricula. The goal of this second study was to better understand inservice science teachers' conceptual models of integrated STEM and explore how these models were realized in the teachers' curriculum writing. Third, a multiple-case study was conducted with three teachers to investigate how the conceptual models held by

  16. Arts Integration: A Classroom Example.

    ERIC Educational Resources Information Center

    Merrion, Margaret Dee; Boothby, Paula R.

    1986-01-01

    To integrate the arts and basic curriculum, teachers used advertising as a theme. Viewing it as a form of communication, they developed an integrated reading/language arts and music unit to strengthen both right and left brain modes of knowing. (LHW)

  17. Integrated Compliance Information System (ICIS)

    EPA Pesticide Factsheets

    The purpose of ICIS is to meet evolving Enforcement and Compliance business needs for EPA and State users by integrating information into a single integrated data system that supports both management and programmatic requirements of the Enforcement and Compliance programs.

  18. Integrated photonics for infrared spectroscopic sensing

    NASA Astrophysics Data System (ADS)

    Lin, Hongtao; Kita, Derek; Han, Zhaohong; Su, Peter; Agarwal, Anu; Yadav, Anupama; Richardson, Kathleen; Gu, Tian; Hu, Juejun

    2017-05-01

    Infrared (IR) spectroscopy is widely recognized as a gold standard technique for chemical analysis. Traditional IR spectroscopy relies on fragile bench-top instruments located in dedicated laboratory settings, and is thus not suitable for emerging field-deployed applications such as in-line industrial process control, environmental monitoring, and point-ofcare diagnosis. Recent strides in photonic integration technologies provide a promising route towards enabling miniaturized, rugged platforms for IR spectroscopic analysis. Chalcogenide glasses, the amorphous compounds containing S, Se or Te, have stand out as a promising material for infrared photonic integration given their broadband infrared transparency and compatibility with silicon photonic integration. In this paper, we discuss our recent work exploring integrated chalcogenide glass based photonic devices for IR spectroscopic chemical analysis, including on-chip cavityenhanced chemical sensing and monolithic integration of mid-IR waveguides with photodetectors.

  19. Integration Testing of Space Flight Systems

    NASA Technical Reports Server (NTRS)

    Sowards, Stephanie; Honeycutt, Timothy

    2008-01-01

    This paper discusses the benefits of conducting multi-system integration testing of space flight elements in lieu of merely shipping and shooting to the launch site and launching. "Ship and shoot" is a philosophy that proposes to transport flight elements directly from the factory to the launch site and begin the mission without further testing. Integration testing, relevant to validation testing in this context, is a risk mitigation effort that builds upon the individual element and system levels of qualification and acceptance tests, greatly improving the confidence of operations in space. The International Space Station Program (ISSP) experience is the focus of most discussions from a historical perspective, while proposed integration testing of the Constellation Program is also discussed. The latter will include Multi-Element Integration Testing (MElT) and Flight Element Integration Testing (FElT).

  20. Finnish care integrated?

    PubMed Central

    Niskanen, J. Jouni

    2002-01-01

    Abstract The public Finnish social and health care system has been challenged by the economic crisis, administrative reforms and increased demands. Better integration as a solution includes many examples, which have been taken to use. The most important are the rewritten national and municipals strategies and quality recommendations, where the different sectors and the levels of care are seen as one entity. Many reorganisations have taken place, both nationally and locally, and welfare clusters have been established. The best examples of integrated care are the forms of teamwork, care management, emphasis on non-institutional care and the information technology. PMID:16896395

  1. Integrated Avionics System (IAS)

    NASA Technical Reports Server (NTRS)

    Hunter, D. J.

    2001-01-01

    As spacecraft designs converge toward miniaturization and with the volumetric and mass constraints placed on avionics, programs will continue to advance the 'state of the art' in spacecraft systems development with new challenges to reduce power, mass, and volume. Although new technologies have improved packaging densities, a total system packaging architecture is required that not only reduces spacecraft volume and mass budgets, but increase integration efficiencies, provide modularity and scalability to accommodate multiple missions. With these challenges in mind, a novel packaging approach incorporates solutions that provide broader environmental applications, more flexible system interconnectivity, scalability, and simplified assembly test and integration schemes. This paper will describe the fundamental elements of the Integrated Avionics System (IAS), Horizontally Mounted Cube (HMC) hardware design, system and environmental test results. Additional information is contained in the original extended abstract.

  2. Chemistry integrated circuit: chemical system on a complementary metal oxide semiconductor integrated circuit.

    PubMed

    Nakazato, Kazuo

    2014-03-28

    By integrating chemical reactions on a large-scale integration (LSI) chip, new types of device can be created. For biomedical applications, monolithically integrated sensor arrays for potentiometric, amperometric and impedimetric sensing of biomolecules have been developed. The potentiometric sensor array detects pH and redox reaction as a statistical distribution of fluctuations in time and space. For the amperometric sensor array, a microelectrode structure for measuring multiple currents at high speed has been proposed. The impedimetric sensor array is designed to measure impedance up to 10 MHz. The multimodal sensor array will enable synthetic analysis and make it possible to standardize biosensor chips. Another approach is to create new functional devices by integrating molecular systems with LSI chips, for example image sensors that incorporate biological materials with a sensor array. The quantum yield of the photoelectric conversion of photosynthesis is 100%, which is extremely difficult to achieve by artificial means. In a recently developed process, a molecular wire is plugged directly into a biological photosynthetic system to efficiently conduct electrons to a gold electrode. A single photon can be detected at room temperature using such a system combined with a molecular single-electron transistor.

  3. An annular superposition integral for axisymmetric radiators.

    PubMed

    Kelly, James F; McGough, Robert J

    2007-02-01

    A fast integral expression for computing the nearfield pressure is derived for axisymmetric radiators. This method replaces the sum of contributions from concentric annuli with an exact double integral that converges much faster than methods that evaluate the Rayleigh-Sommerfeld integral or the generalized King integral. Expressions are derived for plane circular pistons using both continuous wave and pulsed excitations. Several commonly used apodization schemes for the surface velocity distribution are considered, including polynomial functions and a "smooth piston" function. The effect of different apodization functions on the spectral content of the wave field is explored. Quantitative error and time comparisons between the new method, the Rayleigh-Sommerfeld integral, and the generalized King integral are discussed. At all error levels considered, the annular superposition method achieves a speed-up of at least a factor of 4 relative to the point-source method and a factor of 3 relative to the generalized King integral without increasing the computational complexity.

  4. Semantic integration of data on transcriptional regulation.

    PubMed

    Baitaluk, Michael; Ponomarenko, Julia

    2010-07-01

    Experimental and predicted data concerning gene transcriptional regulation are distributed among many heterogeneous sources. However, there are no resources to integrate these data automatically or to provide a 'one-stop shop' experience for users seeking information essential for deciphering and modeling gene regulatory networks. IntegromeDB, a semantic graph-based 'deep-web' data integration system that automatically captures, integrates and manages publicly available data concerning transcriptional regulation, as well as other relevant biological information, is proposed in this article. The problems associated with data integration are addressed by ontology-driven data mapping, multiple data annotation and heterogeneous data querying, also enabling integration of the user's data. IntegromeDB integrates over 100 experimental and computational data sources relating to genomics, transcriptomics, genetics, and functional and interaction data concerning gene transcriptional regulation in eukaryotes and prokaryotes. IntegromeDB is accessible through the integrated research environment BiologicalNetworks at http://www.BiologicalNetworks.org baitaluk@sdsc.edu Supplementary data are available at Bioinformatics online.

  5. An annular superposition integral for axisymmetric radiators

    PubMed Central

    Kelly, James F.; McGough, Robert J.

    2007-01-01

    A fast integral expression for computing the nearfield pressure is derived for axisymmetric radiators. This method replaces the sum of contributions from concentric annuli with an exact double integral that converges much faster than methods that evaluate the Rayleigh-Sommerfeld integral or the generalized King integral. Expressions are derived for plane circular pistons using both continuous wave and pulsed excitations. Several commonly used apodization schemes for the surface velocity distribution are considered, including polynomial functions and a “smooth piston” function. The effect of different apodization functions on the spectral content of the wave field is explored. Quantitative error and time comparisons between the new method, the Rayleigh-Sommerfeld integral, and the generalized King integral are discussed. At all error levels considered, the annular superposition method achieves a speed-up of at least a factor of 4 relative to the point-source method and a factor of 3 relative to the generalized King integral without increasing the computational complexity. PMID:17348500

  6. Scientific Integrity Policy Creation and Implementation.

    NASA Astrophysics Data System (ADS)

    Koizumi, K.

    2017-12-01

    Ensuring the integrity of science was a priority for the Obama Administration. In March 2009, President Obama issued a Presidential Memorandum that recognized the need for the public to be able to trust the science and scientific process informing public policy decisions. In 2010, the White House Office of Science and Technology Policy (OSTP) issued a Memorandum providing guidelines for Federal departments and agencies to follow in developing scientific integrity policies. This Memorandum describes minimum standards for: (1) strengthening the foundations of scientific integrity in government, including by shielding scientific data and analysis from inappropriate political influence; (2) improving public communication about science and technology by promoting openness and transparency; (3) enhancing the ability of Federal Advisory Committees to provide independent scientific advice; and (4) supporting the professional development of government scientists and engineers. The Memorandum called upon the heads of departments and agencies to develop scientific integrity policies that meet these requirements. At the end of the Obama Administration, 24 Federal departments and agencies had developed and implemented scientific integrity policies consistent with the OSTP guidelines. This year, there are significant questions as to the Trump Administration's commitment to these scientific integrity policies and interest in the Congress in codifying these policies in law. The session will provide an update on the status of agency scientific integrity policies and legislation.

  7. Information Systems Integration and Enterprise Application Integration (EAI) Adoption: A Case from Financial Services

    ERIC Educational Resources Information Center

    Lam, Wing

    2007-01-01

    Increasingly, organizations find that they need to integrate large number of information systems in order to support enterprise-wide business initiatives such as e-business, supply chain management and customer relationship management. To date, organizations have largely tended to address information systems (IS) integration in an ad-hoc manner.…

  8. Evaluation of Mean and Variance Integrals without Integration

    ERIC Educational Resources Information Center

    Joarder, A. H.; Omar, M. H.

    2007-01-01

    The mean and variance of some continuous distributions, in particular the exponentially decreasing probability distribution and the normal distribution, are considered. Since they involve integration by parts, many students do not feel comfortable. In this note, a technique is demonstrated for deriving mean and variance through differential…

  9. Leading singularities and off-shell conformal integrals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Drummond, James; Duhr, Claude; Eden, Burkhard

    2013-08-29

    The three-loop four-point function of stress-tensor multiplets in N=4 super Yang-Mills theory contains two so far unknown, off-shell, conformal integrals, in addition to the known, ladder-type integrals. In our paper we evaluate the unknown integrals, thus obtaining the three-loop correlation function analytically. The integrals have the generic structure of rational functions multiplied by (multiple) polylogarithms. We use the idea of leading singularities to obtain the rational coefficients, the symbol — with an appropriate ansatz for its structure — as a means of characterising multiple polylogarithms, and the technique of asymptotic expansion of Feynman integrals to obtain the integrals in certainmore » limits. The limiting behaviour uniquely fixes the symbols of the integrals, which we then lift to find the corresponding polylogarithmic functions. The final formulae are numerically confirmed. Furthermore, we develop techniques that can be applied more generally, and we illustrate this by analytically evaluating one of the integrals contributing to the same four-point function at four loops. This example shows a connection between the leading singularities and the entries of the symbol.« less

  10. Optimal visual-haptic integration with articulated tools.

    PubMed

    Takahashi, Chie; Watt, Simon J

    2017-05-01

    When we feel and see an object, the nervous system integrates visual and haptic information optimally, exploiting the redundancy in multiple signals to estimate properties more precisely than is possible from either signal alone. We examined whether optimal integration is similarly achieved when using articulated tools. Such tools (tongs, pliers, etc) are a defining characteristic of human hand function, but complicate the classical sensory 'correspondence problem' underlying multisensory integration. Optimal integration requires establishing the relationship between signals acquired by different sensors (hand and eye) and, therefore, in fundamentally unrelated units. The system must also determine when signals refer to the same property of the world-seeing and feeling the same thing-and only integrate those that do. This could be achieved by comparing the pattern of current visual and haptic input to known statistics of their normal relationship. Articulated tools disrupt this relationship, however, by altering the geometrical relationship between object properties and hand posture (the haptic signal). We examined whether different tool configurations are taken into account in visual-haptic integration. We indexed integration by measuring the precision of size estimates, and compared our results to optimal predictions from a maximum-likelihood integrator. Integration was near optimal, independent of tool configuration/hand posture, provided that visual and haptic signals referred to the same object in the world. Thus, sensory correspondence was determined correctly (trial-by-trial), taking tool configuration into account. This reveals highly flexible multisensory integration underlying tool use, consistent with the brain constructing internal models of tools' properties.

  11. Integrative medicine in head and neck cancer

    PubMed Central

    Matovina, Chloe; Birkeland, Andrew C.; Zick, Suzanna; Shuman, Andrew G.

    2017-01-01

    Objective Complementary and alternative medicine (CAM), or integrative medicine, has become increasingly popular among patients with head and neck cancer. Despite its increasing prevalence, many patients feel uncomfortable discussing such therapies with their physicians, and many physicians are unaware and underequipped to evaluate or discuss their use with patients. The aim of this manuscript is to use recent data to outline the decision-making inherent to integrative medicine utilization among patients with head and neck cancer, to discuss the ethical implications inherent to balancing integrative and conventional approaches to treatment, and to highlight available resources to enhance head and neck cancer providers’ understanding of integrative medicine. Data Sources Randomized controlled trials involving integrative medicine or CAM treatment for cancer patients. Review Methods Trials were drawn from a systematic PubMed database search categorized into cancer prevention, treatment, and symptom management. Conclusions Integrative medicine is gaining popularity for the management of cancer and is most commonly used for symptom management. A number of randomized controlled trials provide data to support integrative therapies, yet physicians who treat head and neck cancer may be faced with ethical dilemmas and practical barriers surrounding incorporation of integrative medicine. Implications for Practice In the management of head and neck cancer, there is an increasing demand for awareness of, dialogue about, and research evaluating integrative medicine therapies. It is important for otolaryngologists to become aware of integrative therapy options, their risks and benefits, and resources for further information in order to effectively counsel their patients. PMID:27729559

  12. Integrative Medicine in Head and Neck Cancer.

    PubMed

    Matovina, Chloe; Birkeland, Andrew C; Zick, Suzanna; Shuman, Andrew G

    2017-02-01

    Objective Complementary and alternative medicine, or integrative medicine, has become increasingly popular among patients with head and neck cancer. Despite its increasing prevalence, many patients feel uncomfortable discussing such therapies with their physicians, and many physicians are unaware and underequipped to evaluate or discuss their use with patients. The aim of this article is to use recent data to outline the decision making inherent to integrative medicine utilization among patients with head and neck cancer, to discuss the ethical implications inherent to balancing integrative and conventional approaches to treatment, and to highlight available resources to enhance head and neck cancer providers' understanding of integrative medicine. Data Sources Randomized controlled trials involving integrative medicine or complementary and alternative medicine treatment for cancer patients. Review Methods Trials were drawn from a systematic PubMed database search categorized into cancer prevention, treatment, and symptom management. Conclusions Integrative medicine is gaining popularity for the management of cancer and is most commonly used for symptom management. A number of randomized controlled trials provide data to support integrative therapies, yet physicians who treat head and neck cancer may be faced with ethical dilemmas and practical barriers surrounding incorporation of integrative medicine. Implications for Practice In the management of head and neck cancer, there is an increasing demand for awareness of, dialogue about, and research evaluating integrative medicine therapies. It is important for otolaryngologists to become aware of integrative therapy options, their risks and benefits, and resources for further information to effectively counsel their patients.

  13. Integrating to Learn and Learning to Integrate: A Case Study of an Online Master's Program on Science-Mathematics Integration for Middle School Teachers

    ERIC Educational Resources Information Center

    Lee, Mimi Miyoung; Chauvot, Jennifer; Plankis, Brian; Vowell, Julie; Culpepper, Shea

    2011-01-01

    iSMART (Integration of Science, Mathematics, and Reflective Teaching) Program is an online science and mathematics integrated graduate program for middle school teachers across the state of Texas. As part of a large design-based research project, this paper describes the initial stages of the design process of the iSMART program for its first…

  14. Integration of Health Professions Education

    ERIC Educational Resources Information Center

    Heaney, Robert P.

    1975-01-01

    Interdisciplinary integration of health professions education (e.g. pharmacy, medicine, dentistry, nursing, and podiatry) is examined in light of the pros (societal usefulness and cost effectiveness) and cons (justifiable professional boundaries and other concerns). Characteristics of an integrated cluster of individualized, cross-disciplinary…

  15. Integrative Family Therapy: Theoretical Considerations.

    ERIC Educational Resources Information Center

    Walsh, William M.

    Integrative family therapy is an integration of personality theory and counseling theory actualized in the counseling process. Personality theory contributes five interrelated concepts to a model of family therapy, including communication/perception, individual roles, family subunits, family themes, and individual personality dynamics; these…

  16. Clinical results of HIS, RIS, PACS integration using data integration CASE tools

    NASA Astrophysics Data System (ADS)

    Taira, Ricky K.; Chan, Hing-Ming; Breant, Claudine M.; Huang, Lu J.; Valentino, Daniel J.

    1995-05-01

    Current infrastructure research in PACS is dominated by the development of communication networks (local area networks, teleradiology, ATM networks, etc.), multimedia display workstations, and hierarchical image storage architectures. However, limited work has been performed on developing flexible, expansible, and intelligent information processing architectures for the vast decentralized image and text data repositories prevalent in healthcare environments. Patient information is often distributed among multiple data management systems. Current large-scale efforts to integrate medical information and knowledge sources have been costly with limited retrieval functionality. Software integration strategies to unify distributed data and knowledge sources is still lacking commercially. Systems heterogeneity (i.e., differences in hardware platforms, communication protocols, database management software, nomenclature, etc.) is at the heart of the problem and is unlikely to be standardized in the near future. In this paper, we demonstrate the use of newly available CASE (computer- aided software engineering) tools to rapidly integrate HIS, RIS, and PACS information systems. The advantages of these tools include fast development time (low-level code is generated from graphical specifications), and easy system maintenance (excellent documentation, easy to perform changes, and centralized code repository in an object-oriented database). The CASE tools are used to develop and manage the `middle-ware' in our client- mediator-serve architecture for systems integration. Our architecture is scalable and can accommodate heterogeneous database and communication protocols.

  17. [Health in Andean regional integration].

    PubMed

    Agudelo, Carlos A

    2007-01-01

    Despite their shared history, the Andean countries are socially and politically diverse, with heterogeneous health realities and complex integration processes. General developments such as the Latin American Free Trade Association and Latin American Integration Association have existed for decades, along with others of a regional scope, like the Andean Community of Nations, Caribbean Community, and Central American Common Market. The health field has a specific instrument in the Andean Region called the Hipólito Unánue Agreement, created in 1971. Integration processes have concentrated on economic aspects, based on preferential customs agreements that have led to an important long-term increase in trade. Less progress has been made in the field of health in terms of sharing national experiences, knowledge, and capabilities. Analysis of experiences in health has shown that integration depends on the countries' respective strengths and to a major extent on national political processes.

  18. Knowledge Integration in Global R&D Networks

    NASA Astrophysics Data System (ADS)

    Erkelens, Rose; van den Hooff, Bart; Vlaar, Paul; Huysman, Marleen

    This paper reports a qualitative study conducted at multinational organizations' R&D departments about their process of knowledge integration. Taking into account the knowledge based view (KBV) of the firm and the practice-based view of knowledge, and building on the literatures concerning specialization and integration of knowledge in organizations, we explore which factors may have a significant influence on the integration process of knowledge between R&D units. The findings indicated (1) the contribution of relevant factors influencing knowledge integration processes and (2) a thoughtful balance between engineering and emergent approaches to be helpful in understanding and overcoming knowledge integration issues.

  19. Integrating reproductive health: myth and ideology.

    PubMed Central

    Lush, L.; Cleland, J.; Walt, G.; Mayhew, S.

    1999-01-01

    Since 1994, integrating human immunodeficiency virus/sexually transmitted disease (HIV/STD) services with primary health care, as part of reproductive health, has been advocated to address two major public health problems: to control the spread of HIV; and to improve women's reproductive health. However, integration is unlikely to succeed because primary health care and the political context within which this approach is taking place are unsuited to the task. In this paper, a historical comparison is made between the health systems of Ghana, Kenya and Zambia and that of South Africa, to examine progress on integration of HIV/STD services since 1994. Our findings indicate that primary health care in Ghana, Kenya and Zambia has been used mainly by women and children and that integration has meant adding new activities to these services. For the vertical programmes which support these services, integration implies enhanced collaboration rather than merged responsibility. This compromise between comprehensive rhetoric and selective reality has resulted in little change to existing structures and processes; problems with integration have been exacerbated by the activities of external donors. By comparison, in South Africa integration has been achieved through political commitment to primary health care rather than expanding vertical programmes (top-down management systems). The rhetoric of integration has been widely used in reproductive health despite lack of evidence for its feasibility, as a result of the convergence of four agendas: improving family planning quality; the need to improve women's health; the rapid spread of HIV; and conceptual shifts in primary health care. International reproductive health actors, however, have taken little account of political, financial and managerial constraints to implementation in low-income countries. PMID:10534902

  20. Integrated Approaches On Archaeo-Geophysical Data

    NASA Astrophysics Data System (ADS)

    Kucukdemirci, M.; Piro, S.; Zamuner, D.; Ozer, E.

    2015-12-01

    Key words: Ground Penetrating Radar (GPR), Magnetometry, Geophysical Data Integration, Principal Component Analyse (PCA), Aizanoi Archaeological Site An application of geophysical integration methods which often appealed are divided into two classes as qualitative and quantitative approaches. This work focused on the application of quantitative integration approaches, which involve the mathematical and statistical integration techniques, on the archaeo-geophysical data obtained in Aizanoi Archaeological Site,Turkey. Two geophysical methods were applied as Ground Penetrating Radar (GPR) and Magnetometry for archaeological prospection on the selected archaeological site. After basic data processing of each geophysical method, the mathematical approaches of Sums and Products and the statistical approach of Principal Component Analysis (PCA) have been applied for the integration. These integration approches were first tested on synthetic digital images before application to field data. Then the same approaches were applied to 2D magnetic maps and 2D GPR time slices which were obtained on the same unit grids in the archaeological site. Initially, the geophysical data were examined individually by referencing with archeological maps and informations obtained from archaeologists and some important structures as possible walls, roads and relics were determined. The results of all integration approaches provided very important and different details about the anomalies related to archaeological features. By using all those applications, integrated images can provide complementary informations as well about the archaeological relics under the ground. Acknowledgements The authors would like to thanks to Scientific and Technological Research Council of Turkey (TUBITAK), Fellowship for Visiting Scientists Programme for their support, Istanbul University Scientific Research Project Fund, (Project.No:12302) and archaeologist team of Aizanoi Archaeological site for their support

  1. Display integration for ground combat vehicles

    NASA Astrophysics Data System (ADS)

    Busse, David J.

    1998-09-01

    The United States Army's requirement to employ high resolution target acquisition sensors and information warfare to increase its dominance over enemy forces has led to the need to integrate advanced display devices into ground combat vehicle crew stations. The Army's force structure require the integration of advanced displays on both existing and emerging ground combat vehicle systems. The fielding of second generation target acquisition sensors, color digital terrain maps and high volume digital command and control information networks on these platforms define display performance requirements. The greatest challenge facing the system integrator is the development and integration of advanced displays that meet operational, vehicle and human computer interface performance requirements for the ground combat vehicle fleet. The subject of this paper is to address those challenges: operational and vehicle performance, non-soldier centric crew station configurations, display performance limitations related to human computer interfaces and vehicle physical environments, display technology limitations and the Department of Defense (DOD) acquisition reform initiatives. How the ground combat vehicle Program Manager and system integrator are addressing these challenges are discussed through the integration of displays on fielded, current and future close combat vehicle applications.

  2. Integrating traditional Chinese medicine into mainstream healthcare system in Hong Kong, China-A model of integrative medicine in the HKU-SZ Hospital.

    PubMed

    Lao, Lixing; Ning, Zhipeng

    2015-11-01

    The European Congress for Integrative Medicine 2015 Global Summit on Integrative Medicine and Healthcare in Greater Copenhagen has successfully promoted integrative medicine to the public once again. Integrative medicine, which is called the art and science of healthcare by Nordic Integrative Medicine, has been widely used in the world. In Hong Kong, integrated traditional Chinese and Western medicine, which is also known as the Chinese version of integrative medicine, provides a valuable reference for the development of integrative medicine in the world. In this article, we introduce the development of traditional Chinese medicine in Hong Kong and an integrated traditional Chinese and Western medicine model in the University of Hong Kong-Shenzhen Hospital.

  3. Integrated Medical Curriculum: Advantages and Disadvantages

    PubMed Central

    Quintero, Gustavo A.; Vergel, John; Arredondo, Martha; Ariza, María-Cristina; Gómez, Paula; Pinzon-Barrios, Ana-Maria

    2016-01-01

    Most curricula for medical education have been integrated horizontally and vertically–-vertically between basic and clinical sciences. The Flexnerian curriculum has disappeared to permit integration between basic sciences and clinical sciences, which are taught throughout the curriculum. We have proposed a different form of integration where the horizontal axis represents the defined learning outcomes and the vertical axis represents the teaching of the sciences throughout the courses. We believe that a mere integration of basic and clinical sciences is not enough because it is necessary to emphasize the importance of humanism as well as health population sciences in medicine. It is necessary to integrate basic and clinical sciences, humanism, and health population in the vertical axis, not only in the early years but also throughout the curriculum, presupposing the use of active teaching methods based on problems or cases in small groups. PMID:29349303

  4. Residential Segregation and School Integration.

    ERIC Educational Resources Information Center

    Rivkin, Steven G.

    1994-01-01

    Asserts that school districts' efforts to integrate schools have failed to ameliorate the racial isolation of black students. Finds that schools remain segregated primarily because of continued residential segregation and that school integration efforts have had little long-term effect on residential segregation. (CFR)

  5. Support Systems for Treatment Integrity

    ERIC Educational Resources Information Center

    Goense, Pauline Brigitta; Boendermaker, Leonieke; van Yperen, Tom

    2016-01-01

    Objective: This systematic review evaluates the content of effective support provided to practitioners of evidence-based interventions in order to establish and maintain treatment integrity. Method: Four articles covering six outcome studies are included in this review, these studies (1) adequately operationalized treatment integrity procedures…

  6. Austin ISD. Integrated Lesson Plans.

    ERIC Educational Resources Information Center

    East Texas State Univ., Commerce. Educational Development and Training Center.

    This packet contains 14 lesson plans for integrated academic and vocational education courses. Lesson plans for the following courses are included: integrated physics and principles of technology; algebra and principles of technology; principles of technology, language arts, and economics; physics and industrial electronics; physics and…

  7. Technology Integration Experiences of Teachers

    ERIC Educational Resources Information Center

    Çoklar, Ahmet Naci; Yurdakul, Isil Kabakçi

    2017-01-01

    Teachers are important providers of educational sustainability. Teachers' ability to adapt themselves to rapidly developing technologies applicable to learning environments is connected with technology integration. The purpose of this study is to investigate teachers' technology integration experiences in the course of learning and teaching…

  8. Optical systems integrated modeling

    NASA Technical Reports Server (NTRS)

    Shannon, Robert R.; Laskin, Robert A.; Brewer, SI; Burrows, Chris; Epps, Harlan; Illingworth, Garth; Korsch, Dietrich; Levine, B. Martin; Mahajan, Vini; Rimmer, Chuck

    1992-01-01

    An integrated modeling capability that provides the tools by which entire optical systems and instruments can be simulated and optimized is a key technology development, applicable to all mission classes, especially astrophysics. Many of the future missions require optical systems that are physically much larger than anything flown before and yet must retain the characteristic sub-micron diffraction limited wavefront accuracy of their smaller precursors. It is no longer feasible to follow the path of 'cut and test' development; the sheer scale of these systems precludes many of the older techniques that rely upon ground evaluation of full size engineering units. The ability to accurately model (by computer) and optimize the entire flight system's integrated structural, thermal, and dynamic characteristics is essential. Two distinct integrated modeling capabilities are required. These are an initial design capability and a detailed design and optimization system. The content of an initial design package is shown. It would be a modular, workstation based code which allows preliminary integrated system analysis and trade studies to be carried out quickly by a single engineer or a small design team. A simple concept for a detailed design and optimization system is shown. This is a linkage of interface architecture that allows efficient interchange of information between existing large specialized optical, control, thermal, and structural design codes. The computing environment would be a network of large mainframe machines and its users would be project level design teams. More advanced concepts for detailed design systems would support interaction between modules and automated optimization of the entire system. Technology assessment and development plans for integrated package for initial design, interface development for detailed optimization, validation, and modeling research are presented.

  9. GEOSS Water Cycle Integrator

    NASA Astrophysics Data System (ADS)

    Koike, T.; Lawford, R. G.; Cripe, D.

    2012-12-01

    It is critically important to recognize and co-manage the fundamental linkages across the water-dependent domains; land use, including deforestation; ecosystem services; and food-, energy- and health-securities. Sharing coordinated, comprehensive and sustained observations and information for sound decision-making is a first step; however, to take full advantage of these opportunities, we need to develop an effective collaboration mechanism for working together across different disciplines, sectors and agencies, and thereby gain a holistic view of the continuity between environmentally sustainable development, climate change adaptation and enhanced resilience. To promote effective multi-sectoral, interdisciplinary collaboration based on coordinated and integrated efforts, the Global Earth Observation System of Systems (GEOSS) is now developing a "GEOSS Water Cycle Integrator (WCI)", which integrates "Earth observations", "modeling", "data and information", "management systems" and "education systems". GEOSS/WCI sets up "work benches" by which partners can share data, information and applications in an interoperable way, exchange knowledge and experiences, deepen mutual understanding and work together effectively to ultimately respond to issues of both mitigation and adaptation. (A work bench is a virtual geographical or phenomenological space where experts and managers collaborate to use information to address a problem within that space). GEOSS/WCI enhances the coordination of efforts to strengthen individual, institutional and infrastructure capacities, especially for effective interdisciplinary coordination and integration. GEO has established the GEOSS Asian Water Cycle Initiative (AWCI) and GEOSS African Water Cycle Coordination Initiative (AfWCCI). Through regional, inter-disciplinary, multi-sectoral integration and inter-agency coordination in Asia and Africa, GEOSS/WCI is now leading to effective actions and public awareness in support of water security and

  10. Integrated Information and State Differentiation

    PubMed Central

    Marshall, William; Gomez-Ramirez, Jaime; Tononi, Giulio

    2016-01-01

    Integrated information (Φ) is a measure of the cause-effect power of a physical system. This paper investigates the relationship between Φ as defined in Integrated Information Theory and state differentiation (D), the number of, and difference between potential system states. Here we provide theoretical justification of the relationship between Φ and D, then validate the results using a simulation study. First, we show that a physical system in a state with high Φ necessarily has many elements and specifies many causal relationships. Furthermore, if the average value of integrated information across all states is high, the system must also have high differentiation. Next, we explore the use of D as a proxy for Φ using artificial networks, evolved to have integrated structures. The results show a positive linear relationship between Φ and D for multiple network sizes and connectivity patterns. Finally we investigate the differentiation evoked by sensory inputs and show that, under certain conditions, it is possible to estimate integrated information without a direct perturbation of its internal elements. In concluding, we discuss the need for further validation on larger networks and explore the potential applications of this work to the empirical study of consciousness, especially concerning the practical estimation of Φ from neuroimaging data. PMID:27445896

  11. Advanced Integration Matrix Education Outreach

    NASA Technical Reports Server (NTRS)

    Paul Heather L.

    2004-01-01

    The Advanced Integration Matrix (AIM) will design a ground-based test facility for developing revolutionary integrated systems for joint human-robotic missions in order to study and solve systems-level integration issues for exploration missions beyond Low Earth Orbit (LEO). This paper describes development plans for educational outreach activities related to technological and operational integration scenarios similar to the challenges that will be encountered through this project. The education outreach activities will provide hands-on, interactive exercises to allow students of all levels to experience design and operational challenges similar to what NASA deals with everyday in performing the integration of complex missions. These experiences will relate to and impact students everyday lives by demonstrating how their interests in science and engineering can develop into future careers, and reinforcing the concepts of teamwork and conflict resolution. Allowing students to experience and contribute to real-world development, research, and scientific studies of ground-based simulations for complex exploration missions will stimulate interest in the space program, and bring NASA's challenges to the student level. By enhancing existing educational programs and developing innovative activities and presentations, AIM will support NASA s endeavor to "inspire the next generation of explorers.. .as only NASA can."

  12. Integration of Research Studies: Meta-Analysis of Research. Methods of Integrative Analysis; Final Report.

    ERIC Educational Resources Information Center

    Glass, Gene V.; And Others

    Integrative analysis, or what is coming to be known as meta-analysis, is the integration of the findings of many empirical research studies of a topic. Meta-analysis differs from traditional narrative forms of research reviewing in that it is more quantitative and statistical. Thus, the methods of meta-analysis are merely statistical methods,…

  13. Integrated Power Adapter: Isolated Converter with Integrated Passives and Low Material Stress

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2010-09-01

    ADEPT Project: CPES at Virginia Tech is developing an extremely efficient power converter that could be used in power adapters for small, lightweight laptops and other types of mobile electronic devices. Power adapters convert electrical energy into useable power for an electronic device, and they currently waste a lot of energy when they are plugged into an outlet to power up. CPES at Virginia Tech is integrating high-density capacitors, new magnetic materials, high-frequency integrated circuits, and a constant-flux transformer to create its efficient power converter. The high-density capacitors enable the power adapter to store more energy. The new magnetic materialsmore » also increase energy storage, and they can be precisely dispensed using a low-cost ink-jet printer which keeps costs down. The high-frequency integrated circuits can handle more power, and they can handle it more efficiently. And, the constant-flux transformer processes a consistent flow of electrical current, which makes the converter more efficient.« less

  14. Partially integrated exhaust manifold

    DOEpatents

    Hayman, Alan W; Baker, Rodney E

    2015-01-20

    A partially integrated manifold assembly is disclosed which improves performance, reduces cost and provides efficient packaging of engine components. The partially integrated manifold assembly includes a first leg extending from a first port and terminating at a mounting flange for an exhaust gas control valve. Multiple additional legs (depending on the total number of cylinders) are integrally formed with the cylinder head assembly and extend from the ports of the associated cylinder and terminate at an exit port flange. These additional legs are longer than the first leg such that the exit port flange is spaced apart from the mounting flange. This configuration provides increased packaging space adjacent the first leg for any valving that may be required to control the direction and destination of exhaust flow in recirculation to an EGR valve or downstream to a catalytic converter.

  15. Integrative Bioengineering Institute

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eddington, David; Magin,L,Richard; Hetling, John

    2009-01-09

    Microfabrication enables many exciting experimental possibilities for medicine and biology that are not attainable through traditional methods. However, in order for microfabricated devices to have an impact they must not only provide a robust solution to a current unmet need, but also be simple enough to seamlessly integrate into standard protocols. Broad dissemination of bioMEMS has been stymied by the common aim of replacing established and well accepted protocols with equally or more complex devices, methods, or materials. The marriage of a complex, difficult to fabricate bioMEMS device with a highly variable biological system is rarely successful. Instead, the designmore » philosophy of my lab aims to leverage a beneficial microscale phenomena (e.g. fast diffusion at the microscale) within a bioMEMS device and adapt to established methods (e.g. multiwell plate cell culture) and demonstrate a new paradigm for the field (adapt instead of replace). In order for the field of bioMEMS to mature beyond novel proof-of-concept demonstrations, researchers must focus on developing systems leveraging these phenomena and integrating into standard labs, which have largely been ignored. Towards this aim, the Integrative Bioengineering Institute has been established.« less

  16. Bilinearity in Spatiotemporal Integration of Synaptic Inputs

    PubMed Central

    Li, Songting; Liu, Nan; Zhang, Xiao-hui; Zhou, Douglas; Cai, David

    2014-01-01

    Neurons process information via integration of synaptic inputs from dendrites. Many experimental results demonstrate dendritic integration could be highly nonlinear, yet few theoretical analyses have been performed to obtain a precise quantitative characterization analytically. Based on asymptotic analysis of a two-compartment passive cable model, given a pair of time-dependent synaptic conductance inputs, we derive a bilinear spatiotemporal dendritic integration rule. The summed somatic potential can be well approximated by the linear summation of the two postsynaptic potentials elicited separately, plus a third additional bilinear term proportional to their product with a proportionality coefficient . The rule is valid for a pair of synaptic inputs of all types, including excitation-inhibition, excitation-excitation, and inhibition-inhibition. In addition, the rule is valid during the whole dendritic integration process for a pair of synaptic inputs with arbitrary input time differences and input locations. The coefficient is demonstrated to be nearly independent of the input strengths but is dependent on input times and input locations. This rule is then verified through simulation of a realistic pyramidal neuron model and in electrophysiological experiments of rat hippocampal CA1 neurons. The rule is further generalized to describe the spatiotemporal dendritic integration of multiple excitatory and inhibitory synaptic inputs. The integration of multiple inputs can be decomposed into the sum of all possible pairwise integration, where each paired integration obeys the bilinear rule. This decomposition leads to a graph representation of dendritic integration, which can be viewed as functionally sparse. PMID:25521832

  17. Molecular mechanisms of retroviral integration site selection

    PubMed Central

    Kvaratskhelia, Mamuka; Sharma, Amit; Larue, Ross C.; Serrao, Erik; Engelman, Alan

    2014-01-01

    Retroviral replication proceeds through an obligate integrated DNA provirus, making retroviral vectors attractive vehicles for human gene-therapy. Though most of the host cell genome is available for integration, the process of integration site selection is not random. Retroviruses differ in their choice of chromatin-associated features and also prefer particular nucleotide sequences at the point of insertion. Lentiviruses including HIV-1 preferentially integrate within the bodies of active genes, whereas the prototypical gammaretrovirus Moloney murine leukemia virus (MoMLV) favors strong enhancers and active gene promoter regions. Integration is catalyzed by the viral integrase protein, and recent research has demonstrated that HIV-1 and MoMLV targeting preferences are in large part guided by integrase-interacting host factors (LEDGF/p75 for HIV-1 and BET proteins for MoMLV) that tether viral intasomes to chromatin. In each case, the selectivity of epigenetic marks on histones recognized by the protein tether helps to determine the integration distribution. In contrast, nucleotide preferences at integration sites seem to be governed by the ability for the integrase protein to locally bend the DNA duplex for pairwise insertion of the viral DNA ends. We discuss approaches to alter integration site selection that could potentially improve the safety of retroviral vectors in the clinic. PMID:25147212

  18. Planning for Space Station Freedom laboratory payload integration

    NASA Technical Reports Server (NTRS)

    Willenberg, Harvey J.; Torre, Larry P.

    1989-01-01

    Space Station Freedom is being developed to support extensive missions involving microgravity research and applications. Requirements for on-orbit payload integration and the simultaneous payload integration of multiple mission increments will provide the stimulus to develop new streamlined integration procedures in order to take advantage of the increased capabilities offered by Freedom. The United States Laboratory and its user accommodations are described. The process of integrating users' experiments and equipment into the United States Laboratory and the Pressurized Logistics Modules is described. This process includes the strategic and tactical phases of Space Station utilization planning. The support that the Work Package 01 Utilization office will provide to the users and hardware developers, in the form of Experiment Integration Engineers, early accommodation assessments, and physical integration of experiment equipment, is described. Plans for integrated payload analytical integration are also described.

  19. A decade of integration and collaboration: the development of integrated health care in Sweden 2000–2010

    PubMed Central

    Ahgren, Bengt; Axelsson, Runo

    2011-01-01

    Introduction The recent history of integrated health care in Sweden is explored in this article, focusing on the first decade of the 2000s. In addition, there are some reflections about successes and setbacks in this development and challenges for the next decade. Description of policy and practice The first efforts to integrate health care in Sweden appeared in the beginning of the 1990s. The focus was on integration of intra-organisational processes, aiming at a more cost-effective health care provision. Partly as a reaction to the increasing economism at that time, there was also a growing interest in quality improvement. Out of this work emerged the ‘chains of care’, integrating all health care providers involved in the care of specific patient groups. During the 2000s, many county councils have also introduced inter-organisational systems of ‘local health care’. There has also been increasing collaboration between health professionals and other professional groups in different health and welfare services. Discussion and conclusion Local health care meant that the chains of care and other forms of integration and collaboration became embedded in a more integrative context. At the same time, however, policy makers have promoted free patient choice in primary health care and also mergers of hospitals and clinical departments. These policies tend to fragment the provision of health care and have an adverse effect on the development of integrated care. As a counterbalance, more efforts should be put into evaluation of integrated health care, in order to replace political convictions with evidence concerning the benefits of such health care provision. PMID:21677844

  20. Systems Integration | Photovoltaic Research | NREL

    Science.gov Websites

    & Engineering pages: Real-Time PV & Solar Resource Testing Accelerated Testing & Analysis integration support, system-level testing, and systems analysis for the Department of Energy's solar issues and develop solutions for high-penetration grid integration of solar technologies into the

  1. Assessing integrity of insect RNA

    USDA-ARS?s Scientific Manuscript database

    Assessing total RNA integrity is important for the success of downstream RNA applications. The 2100 Bioanalyzer system with the RNA Integrity Number (RIN) provides a quantitative measure of RNA degradation. Although RINs may not be ascertained for RNA from all organisms, namely those with unusual or...

  2. Trigonometric Integration without Trigonometric Functions

    ERIC Educational Resources Information Center

    Quinlan, James; Kolibal, Joseph

    2016-01-01

    Teaching techniques of integration can be tedious and often uninspired. We present an obvious but underutilized approach for finding antiderivatives of various trigonometric functions using the complex exponential representation of the sine and cosine. The purpose goes beyond providing students an alternative approach to trigonometric integrals.…

  3. Semantic integration of data on transcriptional regulation

    PubMed Central

    Baitaluk, Michael; Ponomarenko, Julia

    2010-01-01

    Motivation: Experimental and predicted data concerning gene transcriptional regulation are distributed among many heterogeneous sources. However, there are no resources to integrate these data automatically or to provide a ‘one-stop shop’ experience for users seeking information essential for deciphering and modeling gene regulatory networks. Results: IntegromeDB, a semantic graph-based ‘deep-web’ data integration system that automatically captures, integrates and manages publicly available data concerning transcriptional regulation, as well as other relevant biological information, is proposed in this article. The problems associated with data integration are addressed by ontology-driven data mapping, multiple data annotation and heterogeneous data querying, also enabling integration of the user's data. IntegromeDB integrates over 100 experimental and computational data sources relating to genomics, transcriptomics, genetics, and functional and interaction data concerning gene transcriptional regulation in eukaryotes and prokaryotes. Availability: IntegromeDB is accessible through the integrated research environment BiologicalNetworks at http://www.BiologicalNetworks.org Contact: baitaluk@sdsc.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:20427517

  4. Design Considerations for Proposed Fermilab Integrable RCS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eldred, Jeffrey; Valishev, Alexander

    2017-03-02

    Integrable optics is an innovation in particle accelerator design that provides strong nonlinear focusing while avoiding parametric resonances. One promising application of integrable optics is to overcome the traditional limits on accelerator intensity imposed by betatron tune-spread and collective instabilities. The efficacy of high-intensity integrable accelerators will be undergo comprehensive testing over the next several years at the Fermilab Integrable Optics Test Accelerator (IOTA) and the University of Maryland Electron Ring (UMER). We propose an integrable Rapid-Cycling Synchrotron (iRCS) as a replacement for the Fermilab Booster to achieve multi-MW beam power for the Fermilab high-energy neutrino program. We provide amore » overview of the machine parameters and discuss an approach to lattice optimization. Integrable optics requires arcs with integer-pi phase advance followed by drifts with matched beta functions. We provide an example integrable lattice with features of a modern RCS - long dispersion-free drifts, low momentum compaction, superperiodicity, chromaticity correction, separate-function magnets, and bounded beta functions.« less

  5. RF to millimeter wave integration and module technologies

    NASA Astrophysics Data System (ADS)

    Vähä-Heikkilä, T.

    2015-04-01

    Radio Frequency (RF) consumer applications have boosted silicon integrated circuits (IC) and corresponding technologies. More and more functions are integrated to ICs and their performance is also increasing. However, RF front-end modules with filters and switches as well as antennas still need other way of integration. This paper focuses to RF front-end module and antenna developments as well as to the integration of millimeter wave radios. VTT Technical Research Centre of Finland has developed both Low Temperature Co-fired Ceramics (LTCC) and Integrated Passive Devices (IPD) integration platforms for RF and millimeter wave integrated modules. In addition to in-house technologies, VTT is using module and component technologies from other commercial sources.

  6. IDC Integrated Master Plan.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Clifford, David J.; Harris, James M.

    2014-12-01

    This is the IDC Re-Engineering Phase 2 project Integrated Master Plan (IMP). The IMP presents the major accomplishments planned over time to re-engineer the IDC system. The IMP and the associate Integrated Master Schedule (IMS) are used for planning, scheduling, executing, and tracking the project technical work efforts. REVISIONS Version Date Author/Team Revision Description Authorized by V1.0 12/2014 IDC Re- engineering Project Team Initial delivery M. Harris

  7. The Integrated Medical Model

    NASA Technical Reports Server (NTRS)

    Kerstman, Eric; Minard, Charles; Saile, Lynn; Freiere deCarvalho, Mary; Myers, Jerry; Walton, Marlei; Butler, Douglas; Iyengar, Sriram; Johnson-Throop, Kathy; Baumann, David

    2010-01-01

    The goals of the Integrated Medical Model (IMM) are to develop an integrated, quantified, evidence-based decision support tool useful to crew health and mission planners and to help align science, technology, and operational activities intended to optimize crew health, safety, and mission success. Presentation slides address scope and approach, beneficiaries of IMM capabilities, history, risk components, conceptual models, development steps, and the evidence base. Space adaptation syndrome is used to demonstrate the model's capabilities.

  8. Energy Systems Integration: Demonstrating Distribution Feeder Voltage Control

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2017-01-01

    Overview fact sheet about the Smarter Grid Solutions Integrated Network Testbed for Energy Grid Research and Technology Experimentation (INTEGRATE) project at the Energy Systems Integration Facility. INTEGRATE is part of the U.S. Department of Energy's Grid Modernization Initiative.

  9. Integrating Variable Renewable Energy - Russia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    To foster sustainable, low-emission development, many countries are establishing ambitious renewable energy targets for their electricity supply. Because solar and wind tend to be more variable and uncertain than conventional sources, meeting these targets will involve changes to power system planning and operations. Grid integration is the practice of developing efficient ways to deliver variable renewable energy (VRE) to the grid. Good integration methods maximize the cost-effectiveness of incorporating VRE into the power system while maintaining or increasing system stability and reliability. When considering grid integration, policy makers, regulators, and system operators consider a variety of issues, which can bemore » organized into four broad topics: New Renewable Energy Generation, New Transmission, Increased System Flexibility, Planning for a High RE Future. This is a Russian-language translation of Integrating Variable Renewable Energy into the Grid: Key Issues, Greening the Grid, originally published in English in May 2015.« less

  10. Feature integration across space, time, and orientation

    PubMed Central

    Otto, Thomas U.; Öğmen, Haluk; Herzog, Michael H.

    2012-01-01

    The perception of a visual target can be strongly influenced by flanking stimuli. In static displays, performance on the target improves when the distance to the flanking elements increases- proposedly because feature pooling and integration vanishes with distance. Here, we studied feature integration with dynamic stimuli. We show that features of single elements presented within a continuous motion stream are integrated largely independent of spatial distance (and orientation). Hence, space based models of feature integration cannot be extended to dynamic stimuli. We suggest that feature integration is guided by perceptual grouping operations that maintain the identity of perceptual objects over space and time. PMID:19968428

  11. Integrated control system for electron beam processes

    NASA Astrophysics Data System (ADS)

    Koleva, L.; Koleva, E.; Batchkova, I.; Mladenov, G.

    2018-03-01

    The ISO/IEC 62264 standard is widely used for integration of the business systems of a manufacturer with the corresponding manufacturing control systems based on hierarchical equipment models, functional data and manufacturing operations activity models. In order to achieve the integration of control systems, formal object communication models must be developed, together with manufacturing operations activity models, which coordinate the integration between different levels of control. In this article, the development of integrated control system for electron beam welding process is presented as part of a fully integrated control system of an electron beam plant, including also other additional processes: surface modification, electron beam evaporation, selective melting and electron beam diagnostics.

  12. Energy Systems Integration News | Energy Systems Integration Facility |

    Science.gov Websites

    for its novel approach to energy reduction. The ultra-efficient ESIF data center features a chiller "chips to bricks" approach to sustainability integrates the data center into the facility systems, rather than trying to optimize each in isolation. Key to the approach was collaboration with

  13. International Space Station Payload Operations Integration

    NASA Technical Reports Server (NTRS)

    Fanske, Elizabeth Anne

    2011-01-01

    The Payload Operations Integrator (POINT) plays an integral part in the Certification of Flight Readiness process for the Mission Operations Laboratory and the Payload Operations Integration Function that supports International Space Station Payload operations. The POINTs operate in support of the POIF Payload Operations Manager to bring together and integrate the Certification of Flight Readiness inputs from various MOL teams through maintaining an open work tracking log. The POINTs create monthly metrics for current and future payloads that the Payload Operations Integration Function supports. With these tools, the POINTs assemble the Certification of Flight Readiness package before a given flight, stating that the Mission Operations Laboratory is prepared to support it. I have prepared metrics for Increment 29/30, maintained the Open Work Tracking Logs for Flights ULF6 (STS-134) and ULF7 (STS-135), and submitted the Mission Operations Laboratory Certification of Flight Readiness package for Flight 44P to the Mission Operations Directorate (MOD/OZ).

  14. Integrated feeds for electronically reconfigurable apertures

    NASA Astrophysics Data System (ADS)

    Nicholls, Jeffrey Grant

    With the increasing ubiquity of wireless technology, the need for lower-profile, electronically reconfigurable, highly-directive beam-steering antennas is increasing. This thesis proposes a new electronic beam-steering antenna architecture which combines the full-space beam-steering properties of reflectarrays and transmitarrays with the low-profile feeding characteristics of leaky-wave antennas. Two designs are developed: an integrated feed reflectarray and an integrated feed transmitarray, both of which integrate a leaky-wave feed directly next to the reconfigurable aperture itself. The integrated feed transmitarray proved to be the better architecture due to its simpler design and better performance. A 6-by-6 element array was fabricated and experimentally verified, and full-space (both azimuth and elevation) beam-steering was demonstrated at angles up to 45 degrees off broadside. In addition to the reduction in profile, the integrated feed design enables robust fixed control of the amplitude distribution across the aperture, a characteristic not as easily attained in typical reflectarrays/transmitarrays.

  15. Immigrant community integration in world cities

    PubMed Central

    Lamanna, Fabio; Lenormand, Maxime; Salas-Olmedo, María Henar; Romanillos, Gustavo; Gonçalves, Bruno

    2018-01-01

    As a consequence of the accelerated globalization process, today major cities all over the world are characterized by an increasing multiculturalism. The integration of immigrant communities may be affected by social polarization and spatial segregation. How are these dynamics evolving over time? To what extent the different policies launched to tackle these problems are working? These are critical questions traditionally addressed by studies based on surveys and census data. Such sources are safe to avoid spurious biases, but the data collection becomes an intensive and rather expensive work. Here, we conduct a comprehensive study on immigrant integration in 53 world cities by introducing an innovative approach: an analysis of the spatio-temporal communication patterns of immigrant and local communities based on language detection in Twitter and on novel metrics of spatial integration. We quantify the Power of Integration of cities –their capacity to spatially integrate diverse cultures– and characterize the relations between different cultures when acting as hosts or immigrants. PMID:29538383

  16. Techniques for integrating ‐omics data

    PubMed Central

    Akula, Siva Prasad; Miriyala, Raghava Naidu; Thota, Hanuman; Rao, Allam Appa; Gedela, Srinubabu

    2009-01-01

    The challenge for -omics research is to tackle the problem of fragmentation of knowledge by integrating several sources of heterogeneous information into a coherent entity. It is widely recognized that successful data integration is one of the keys to improve productivity for stored data. Through proper data integration tools and algorithms, researchers may correlate relationships that enable them to make better and faster decisions. The need for data integration is essential for present ‐omics community, because ‐omics data is currently spread world wide in wide variety of formats. These formats can be integrated and migrated across platforms through different techniques and one of the important techniques often used is XML. XML is used to provide a document markup language that is easier to learn, retrieve, store and transmit. It is semantically richer than HTML. Here, we describe bio warehousing, database federation, controlled vocabularies and highlighting the XML application to store, migrate and validate -omics data. PMID:19255651

  17. Sustainable NREL: From Integration to Innovation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2015-09-01

    NREL's sustainability practices are integrated throughout the laboratory and are essential to our mission to develop clean energy and energy efficiency technologies and practices, advance related science and engineering, and provide knowledge and innovations to integrate energy systems at all scales. Sustainability initiatives are integrated through our campus, our staff, and our environment allowing NREL to provide leadership in modeling a sustainability energy future for companies, organizations, governments, and communities.

  18. Generalizations of polylogarithms for Feynman integrals

    NASA Astrophysics Data System (ADS)

    Bogner, Christian

    2016-10-01

    In this talk, we discuss recent progress in the application of generalizations of polylogarithms in the symbolic computation of multi-loop integrals. We briefly review the Maple program MPL which supports a certain approach for the computation of Feynman integrals in terms of multiple polylogarithms. Furthermore we discuss elliptic generalizations of polylogarithms which have shown to be useful in the computation of the massive two-loop sunrise integral.

  19. Miniaturized GPS/MEMS IMU integrated board

    NASA Technical Reports Server (NTRS)

    Lin, Ching-Fang (Inventor)

    2012-01-01

    This invention documents the efforts on the research and development of a miniaturized GPS/MEMS IMU integrated navigation system. A miniaturized GPS/MEMS IMU integrated navigation system is presented; Laser Dynamic Range Imager (LDRI) based alignment algorithm for space applications is discussed. Two navigation cameras are also included to measure the range and range rate which can be integrated into the GPS/MEMS IMU system to enhance the navigation solution.

  20. Tool Integration Framework for Bio-Informatics

    DTIC Science & Technology

    2007-04-01

    Java NetBeans [11] based Integrated Development Environment (IDE) for developing modules and packaging computational tools. The framework is extremely...integrate an Eclipse front-end for Desktop Integration. Eclipse was chosen over Netbeans owing to a higher acceptance, better infrastructure...5.0. This version of Dashboard ran with NetBeans IDE 3.6 requiring Java Runtime 1.4 on a machine with Windows XP. The toolchain is executed by

  1. Salmonella Weltevreden in integrated and non-integrated tilapia aquaculture systems in Guangdong, China.

    PubMed

    Li, Kang; Petersen, Gitte; Barco, Lisa; Hvidtfeldt, Kristian; Liu, Liping; Dalsgaard, Anders

    2017-08-01

    Integrated tilapia-pig farming, which uses manure from pigs as fertilizers in fish pond, is a traditional and common production system practised by small-scale farmers in South-east Asia. Although such systems may be environmentally sustainable, they also pose potential food safety hazards including transmission of faecal zoonotic pathogens and accumulation of antimicrobial and other chemical residues. This study aimed to determine differences in occurrence and characteristics of Salmonella spp. isolated from tilapia-pig and non-integrated aquaculture systems in Guangdong province, China. A total of 77 samples (9 pig feed, 19 fish feed, 9 pig faeces, 20 fish mucus and 20 fish intestine) from 10 tilapia-pig ponds and 10 non-integrated ponds were analysed. Salmonella spp. was found in fish mucus (20.0%), fish intestine (40.0%) and pig faeces (11.1%) from integrated ponds, and from fish mucus (40.0%) and fish intestine (40.0%) from non-integrated ponds. S. Weltevreden (76.5%) was by far the most common serovar showing limited antimicrobial resistance. One pig faeces sample contained S. Typhimurium whereas feed samples were found free of Salmonella spp.. DNA fingerprinting by the PFGE method showed a clonal relationship of S. Weltevreden which was supported by similar antimicrobial resistance patterns (sulfamethoxazole and trimethoprim resistance) as well as most isolates harbouring a 147-kb sized plasmid. The common finding of S. Weltevreden in both tilapia production systems indicates that this serovar may have a different ecology and increased survival in aquaculture environments in comparison with other Salmonella serovars. Further in vivo studies of the ecology of S. Weltevreden in aquaculture environments are needed. Copyright © 2017. Published by Elsevier Ltd.

  2. Overview of integrative tools and methods in assessing ecological integrity in estuarine and coastal systems worldwide.

    PubMed

    Borja, Angel; Bricker, Suzanne B; Dauer, Daniel M; Demetriades, Nicolette T; Ferreira, João G; Forbes, Anthony T; Hutchings, Pat; Jia, Xiaoping; Kenchington, Richard; Carlos Marques, João; Zhu, Changbo

    2008-09-01

    In recent years, several sets of legislation worldwide (Oceans Act in USA, Australia or Canada; Water Framework Directive or Marine Strategy in Europe, National Water Act in South Africa, etc.) have been developed in order to address ecological quality or integrity, within estuarine and coastal systems. Most such legislation seeks to define quality in an integrative way, by using several biological elements, together with physico-chemical and pollution elements. Such an approach allows assessment of ecological status at the ecosystem level ('ecosystem approach' or 'holistic approach' methodologies), rather than at species level (e.g. mussel biomonitoring or Mussel Watch) or just at chemical level (i.e. quality objectives) alone. Increasing attention has been paid to the development of tools for different physico-chemical or biological (phytoplankton, zooplankton, benthos, algae, phanerogams, fishes) elements of the ecosystems. However, few methodologies integrate all the elements into a single evaluation of a water body. The need for such integrative tools to assess ecosystem quality is very important, both from a scientific and stakeholder point of view. Politicians and managers need information from simple and pragmatic, but scientifically sound methodologies, in order to show to society the evolution of a zone (estuary, coastal area, etc.), taking into account human pressures or recovery processes. These approaches include: (i) multidisciplinarity, inherent in the teams involved in their implementation; (ii) integration of biotic and abiotic factors; (iii) accurate and validated methods in determining ecological integrity; and (iv) adequate indicators to follow the evolution of the monitored ecosystems. While some countries increasingly use the establishment of marine parks to conserve marine biodiversity and ecological integrity, there is awareness (e.g. in Australia) that conservation and management of marine ecosystems cannot be restricted to Marine Protected

  3. The Community for Data Integration (CDI): Building Knowledge, Networks, and Integrated Science Capacity

    NASA Astrophysics Data System (ADS)

    Hsu, L.

    2017-12-01

    In 2009, the U.S. Geological Survey determined that a focused effort on data integration was necessary to capture the full scientific potential of its topically and geographically diverse data assets. The Community for Data Integration was established to fill this role, and an emphasis emerged on grassroots learning and solving of shared data integration and management challenges. Now, eight years later, the CDI has grown to over 700 members and runs monthly presentations, working groups, special training events, and an annual USGS-wide grants program. With a diverse membership of scientists, technologists, data managers, program managers, and others, there are a wide range of motivations and interests competing to drive the direction of the community. Therefore, an important role of the community coordinators is to prioritize member interests while valuing and considering many different viewpoints. To do this, new tools and mechanisms are frequently introduced to circulate information and obtain community input and feedback. The coordinators then match community interests with opportunities to address USGS priorities. As a result, the community has facilitated the implementation of USGS-wide data policies and data management procedures, produced guidelines and lessons learned for technologies like mobile applications and use of semantic web technologies, and developed technical recommendations to enable integrated science capacity for USGS leadership.

  4. Learning Factory--Integrative E-Learning

    ERIC Educational Resources Information Center

    Steininger, Peter

    2017-01-01

    Integrative E-Learning (IEP): The goal of the project is the development and testing of an integrative teaching format for the assembly of imported, tried and tested (classic) teaching elements (e.g. wallboard and flipchart, screen walls and other visualization aids, Projector, manuscripts, and workbooks, etc.), with contemporary, innovative…

  5. Integrative approaches: promoting socioecological resilience

    Treesearch

    J.W. Long; Carl Skinner; M. North; C.T. Hunsaker; L. Quinn-Davidson

    2014-01-01

    This chapter begins by discussing current challenges for ecosystem management that emerged from multiple chapters of the full synthesis. It then considers integrative approaches to promote resilience, including general strategies that recognize the integrated nature of socioecological systems, the importance of promoting disturbance regimes upon which these systems...

  6. Nursing Faculty and Academic Integrity

    ERIC Educational Resources Information Center

    Wilson, Cecilia E.

    2013-01-01

    Insufficient information exists regarding the process influencing faculty decisions, specifically in the area of maintaining academic integrity in an online environment. The purpose of the study was to explore the experiences and decision-making process of nursing faculty related to maintaining academic integrity in an online environment. The…

  7. Study of heat and salt transport processes in the Espinheiro Channel (Ria de Aveiro)

    NASA Astrophysics Data System (ADS)

    Vaz, Nuno Alexandre Firmino

    O principal objectivo deste trabalho consistiu no estudo da dinâmica termohalina do Canal do Espinheiro em funcao de dois forcamentos principais: mare e caudal fluvial, usando duas abordagens distintas: trabalho experimental e modelacao numerica. A propagacao da mare e o caudal fluvial do Rio Vouga sao determinantes no estabelecimento da estrutura horizontal da salinidade ao longo do canal. A estrutura termica horizontal ao longo do canal e, em grande parte, determinada pela variacao sazonal da temperatura da agua do Rio Vouga, bem como, pela variacao sazonal das condicoes meteorologicas devido a reduzida profundidade. Foi observada a formacao de fortes gradientes de salinidade (relacionados com a formacao de frentes estuarinas) numa regiao a cerca de 7-8 km da embocadura do canal, observando-se a sua migracao numa regiao de aproximadamente 1 km, dependendo do regime de mare. O balanco entre o transporte de sal de natureza advectiva e difusiva foi calculado, revelando que junto a embocadura os processos fisicos que mais contribuem para o transporte de sal sao a circulacao residual e o aprisionamento da agua em canais secundarios. Junto a foz do Rio Vouga os termos devidos a descarga fluvial e a circulacao gravitacional dominam o transporte de sal. Foi calibrado e validado um modelo numerico (Mohid, em modo 2D e 3D), sendo posteriormente utilizado para estudar a hidrologia do canal. Foi concedida particular atencao ao estudo da hidrologia em condicoes extremas de caudal fluvial e de mare. Os resultados da modelacao numerica permitiram numa primeira fase avaliar o bom desempenho do Mohid na reproducao dos escoamentos barotropicos na Ria de Aveiro, bem como na evolucao temporal das propriedades termohalinas da agua. Sob condicoes de caudal fluvial reduzido, a dinâmica do canal e essencialmente dominada pela mare. Com o aumento do caudal fluvial, a influencia da agua doce estende-se para jusante, estratificando a coluna de agua. As simulacoes 3D do Canal do

  8. Integrative modules for efficient genome engineering in yeast

    PubMed Central

    Amen, Triana; Kaganovich, Daniel

    2017-01-01

    We present a set of vectors containing integrative modules for efficient genome integration into the commonly used selection marker loci of the yeast Saccharomyces cerevisiae. A fragment for genome integration is generated via PCR with a unique set of short primers and integrated into HIS3, URA3, ADE2, and TRP1 loci. The desired level of expression can be achieved by using constitutive (TEF1p, GPD1p), inducible (CUP1p, GAL1/10p), and daughter-specific (DSE4p) promoters available in the modules. The reduced size of the integrative module compared to conventional integrative plasmids allows efficient integration of multiple fragments. We demonstrate the efficiency of this tool by simultaneously tagging markers of the nucleus, vacuole, actin, and peroxisomes with genomically integrated fluorophores. Improved integration of our new pDK plasmid series allows stable introduction of several genes and can be used for multi-color imaging. New bidirectional promoters (TEF1p-GPD1p, TEF1p-CUP1p, and TEF1p-DSE4p) allow tractable metabolic engineering. PMID:28660202

  9. Guest editorial. Integrated healthcare information systems.

    PubMed

    Li, Ling; Ge, Ri-Li; Zhou, Shang-Ming; Valerdi, Ricardo

    2012-07-01

    The use of integrated information systems for healthcare has been started more than a decade ago. In recent years, rapid advances in information integration methods have spurred tremendous growth in the use of integrated information systems in healthcare delivery. Various techniques have been used for probing such integrated systems. These techniques include service-oriented architecture (SOA), EAI, workflow management, grid computing, and others. Many applications require a combination of these techniques, which gives rise to the emergence of enterprise systems in healthcare. Development of the techniques originated from different disciplines has the potential to significantly improve the performance of enterprise systems in healthcare. This editorial paper briefly introduces the enterprise systems in the perspective of healthcare informatics.

  10. Integrative Approaches in Pediatric Palliative Care.

    PubMed

    Shafto, Kate; Gouda, Suzanne; Catrine, Kris; Brown, Melanie L

    2018-06-13

    Pediatric palliative care is a field which focuses on caring for and treating the symptoms and distress typically associated with life-limiting illness. Integrative medicine is supported by evidence and aims to heal the whole person, including all aspects of one’s lifestyle. Therapies offered by integrative medicine often empower patients and families, allowing for a sense of control. This review addresses the merging of integrative medicine philosophy and modalities with the care given to children with life-limiting illness. We review an introduction to integrative medicine, trends in its incorporation in the healthcare setting, application to patients receiving palliative care and the management of specific symptoms. A case study is offered to illustrate these principles.

  11. Integrated Work Management: Overview, Course 31881

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Simpson, Lewis Edward

    Integrated work management (IWM) is the process used for formally implementing the five-step process associated with integrated safety management (ISM) and integrated safeguards and security management (ISSM) at Los Alamos National Laboratory (LANL). IWM also directly supports the LANL Environmental Management System (EMS). IWM helps all workers and managers perform work safely and securely and in a manner that protects people, the environment, property, and the security of the nation. The IWM process applies to all work activities at LANL, from working in the office to designing experiments to assembling and detonating explosives. The primary LANL document that establishes andmore » describes IWM requirements is Procedure (P) 300, Integrated Work Management.« less

  12. An automated integration-free path-integral method based on Kleinert's variational perturbation theory

    NASA Astrophysics Data System (ADS)

    Wong, Kin-Yiu; Gao, Jiali

    2007-12-01

    Based on Kleinert's variational perturbation (KP) theory [Path Integrals in Quantum Mechanics, Statistics, Polymer Physics, and Financial Markets, 3rd ed. (World Scientific, Singapore, 2004)], we present an analytic path-integral approach for computing the effective centroid potential. The approach enables the KP theory to be applied to any realistic systems beyond the first-order perturbation (i.e., the original Feynman-Kleinert [Phys. Rev. A 34, 5080 (1986)] variational method). Accurate values are obtained for several systems in which exact quantum results are known. Furthermore, the computed kinetic isotope effects for a series of proton transfer reactions, in which the potential energy surfaces are evaluated by density-functional theory, are in good accordance with experiments. We hope that our method could be used by non-path-integral experts or experimentalists as a "black box" for any given system.

  13. European Universities' Guidance on Research Integrity and Misconduct.

    PubMed

    Aubert Bonn, Noémie; Godecharle, Simon; Dierickx, Kris

    2017-02-01

    Research integrity is imperative to good science. Nonetheless, many countries and institutions develop their own integrity guidance, thereby risking incompatibilities with guidance of collaborating institutions. We retrieved guidance for academic integrity and misconduct of 18 universities from 10 European countries and investigated accessibility, general content, principles endorsed, and definitions of misconduct. Accessibility and content differ substantially between institutions. There are general trends of common principles of integrity and definitions of misconduct, yet differences remain. Parallel with previous research, we distinguish different approaches in integrity guidance; one emphasizes broad values of integrity, and the other details negative behaviors of misconduct. We propose that a balance between both approaches is necessary to preserve trust, meaning, and realism of guidance on research integrity.

  14. Interpretations of integration in early accountable care organizations.

    PubMed

    Kreindler, Sara A; Larson, Bridget K; Wu, Frances M; Carluzzo, Kathleen L; Gbemudu, Josette N; Struthers, Ashley; VAN Citters, Aricca D; Shortell, Stephen M; Nelson, Eugene C; Fisher, Elliott S

    2012-09-01

    It is widely hoped that accountable care organizations (ACOs) will improve health care quality and reduce costs by fostering integration among diverse provider groups. But how do implementers actually envision integration, and what will integration mean in terms of managing the many social identities that ACOs bring together? Using the lens of the social identity approach, this qualitative study examined how four nascent ACOs engaged with the concept of integration. During multiday site visits, we conducted interviews (114 managers and physicians), observations, and document reviews. In no case was the ACO interpreted as a new, overarching entity uniting disparate groups; rather, each site offered a unique interpretation that flowed from its existing strategies for social-identity management: An independent practice association preserved members' cherished value of autonomy by emphasizing coordination, not "integration"; a medical group promoted integration within its employed core, but not with affiliates; a hospital, engaging community physicians who mistrusted integrated systems, reimagined integration as an equal partnership; an integrated delivery system advanced its careful journey towards intergroup consensus by presenting the ACO as a cultural, not structural, change. The ACO appears to be a model flexible enough to work in synchrony with whatever social strategies are most context appropriate, with the potential to promote alignment and functional integration without demanding common identification with a superordinate group. "Soft integration" may be a promising alternative to the vertically integrated model that, though widely assumed to be ideal, has remained unattainable for most organizations. © 2012 Milbank Memorial Fund.

  15. Integrational Linguistics and the Structuralist Legacy.

    ERIC Educational Resources Information Center

    Harris, Roy

    1999-01-01

    Examines attempts to extend Ferdinand de Saussure's structuralist linguistic theory, particularly those by integrational linguists. Discusses the place of integrational linguistics with regard to Saussurean work. (MSE)

  16. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Integrated baseline...

  17. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Integrated baseline...

  18. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Integrated baseline...

  19. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Integrated baseline...

  20. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Integrated baseline...