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Sample records for agudo severo sras

  1. Microstructure Imaging Using Frequency Spectrum Spatially Resolved Acoustic Spectroscopy F-Sras

    NASA Astrophysics Data System (ADS)

    Sharples, S. D.; Li, W.; Clark, M.; Somekh, M. G.

    2010-02-01

    Material microstructure can have a profound effect on the mechanical properties of a component, such as strength and resistance to creep and fatigue. SRAS—spatially resolved acoustic spectroscopy—is a laser ultrasonic technique which can image microstructure using highly localized surface acoustic wave (SAW) velocity as a contrast mechanism, as this is sensitive to crystallographic orientation. The technique is noncontact, nondestructive, rapid, can be used on large components, and is highly tolerant of acoustic aberrations. Previously, the SRAS technique has been demonstrated using a fixed frequency excitation laser and a variable grating period (к-vector) to determine the most efficiently generated SAWs, and hence the velocity. Here, we demonstrate an implementation which uses a fixed grating period with a broadband laser excitation source. The velocity is determined by analyzing the measured frequency spectrum. Experimental results using this "frequency spectrum SRAS" (f-SRAS) method are presented. Images of microstructure on an industrially relevant material are compared to those obtained using the previous SRAS method ("k-SRAS"), excellent agreement is observed. Moreover, f-SRAS is much simpler and potentially much more rapid than k-SRAS as the velocity can be determined at each sample point in one single laser shot, rather than scanning the grating period.

  2. Optical characterization of the 62-cm telescope at the Severo Diaz Galindo Observatory in Guadalajara

    NASA Astrophysics Data System (ADS)

    Nuñez, J. Manuel; de la Fuente, Eduardo; Luna, Esteban; Herrera, Joel; Velazquez, Enrique; García, Fernando; López, Eduardo; Váldez, Jorge; García, Benjamín; Martínez, Benjamín; Guisa, Gerardo; Quiroz, Fernando; Colorado, Enrique; Ochoa, José Luis; Almaguer, Jaime; Chávez, Arturo

    2009-09-01

    We present the results of the optical characterization of the mirrors of the telescope of 62cm observatory "SEVERO DIAZ GALINDO" property of the University of Guadalajara. We use the Ronchi test and a spherometer to measure by first time, the radius of curvature for the primary and secondary mirror, the parameters of the telescope system were obtained by using the commercial software ZEMAX. We confirm that both mirrors are adequate to work in the telescope configuration and to do optical astronomy.

  3. EJERCICIO Y LA DETECCION DEL MAL AGUDO DE MONTAÑA GRAVE

    PubMed Central

    Garófoli, Adrián; Montoya, Paola; Elías, Carlos; Benzo, Roberto

    2012-01-01

    El Mal Agudo de Montaña (MAM) es un conjunto de síntomas inespecíficos padecidos por sujetos que ascienden rápidamente desde baja a alta altura sin adecuada aclimatación. Usualmente es autolimitado, pero las formas graves (edema pulmonar y cerebral) pueden causar la muerte. La hipoxemia exagerada en reposo está relacionada con el desarrollo de MAM pero su valor predictivo es limitado. Dado que el ejercicio en altura se acompaña de mayor hipoxemia y síntomas, postulamos el valor predictivo de un simple test de ejercicio para pronosticar MAM grave. Se estudió el valor predictivo de la saturación de oxígeno en reposo y ejercicio submáximo a 2 700m y 4 300m en 63 sujetos que ascendían al cerro Aconcagua (6 962m). Se consideró desaturación de oxígeno con ejercicio a una disminución >=5% respecto al reposo. Se utilizó la escala de Lake-Louise para establecer la presencia de MAM grave. 6 sujetos presentaron MAM grave (9.5%) y requirieron evacuación. La saturación de oxígeno en reposo a 2 700m no fue significativa para clasificar sujetos que luego desarrollaron MAM grave. Por el contrario, la asociación de desaturación durante el ejercicio a 2 700m más la saturación inapropiada en reposo a 4 300m fue significativa para clasificar a los sujetos que desarrollaron MAM grave con un valor predictivo positivo de 80% y un valor predictivo negativo del 97%. Nuestros resultados son relevantes para el montañismo y sugieren la adición de un simple test de ejercicio en la predicción del MAM grave. PMID:20228017

  4. Assessing the impact of soil management on soil erosion in vineyards in La Rioja (Spain): La Sierra de Los Agudos

    NASA Astrophysics Data System (ADS)

    Galilea Salvador, Ianire; Lana-Renault, Noemí; Ruiz Flaño, Purificación; Ángel Llorente Adán, Jose; Bellido, Nuria Pascual

    2015-04-01

    La Rioja is a predominantly agricultural region located in the northwestern corner of the Ebro Basin in Spain. In this region, vineyards are a crop of historical and economical importance and large extension that traditionally has been relegated to marginal lands, mainly glacis, high fluvial terraces and slopes linking different levels of terraces and glacis. It is well known that vineyards are among the land uses affected by largest soil erosion losses. Surprisingly, many farmers still apply non-conservative practices that contribute to an increase of soil erosion. In spite of the environmental and economic consequences, very little research on this topic has been undertaken in the region. In this study, we assessed the impact of vineyards and soil management practices on soil erosion in La Sierra de Los Agudos, a heavily eroded area located on quaternary silt loam and clay glacis, where vineyards represent 30% of the agricultural land. For this purpose we used an adapted version of the RUSLE model: R was estimated using data from two nearby weather stations following the methodology of Arnoldus and Fournier for a lapse time of five years; K was assessed from 28 soil samples analyzed by the National Institute of Soil Erosion, and the edaphic map of La Rioja which includes 32 taxa; C was calculated from catastral data, the Information System of Land Occupation, and by a detailed study of each subfactor; LS was obtained from a 10 meters/pixel scale DTM from which the slope length and the percentage of inclination of the slopes was calculated; and P was established by observing different tillage practices in each of the plots. Low erosion values (<0,001-2 Mg ha-¹year-¹) were estimated for the 43 % of the area, while the 37% was affected by moderate (2-12 Mg ha-¹year-¹) and high erosion values (>12 Mg ha-¹year-¹) which exceed the soil loss tolerance (T value) established by Renard (1996). In this study we showed that the current support practices accelerate soil

  5. Materials Data on Sr(As3Pt2)2 (SG:15) by Materials Project

    SciTech Connect

    Kristin Persson

    2015-02-18

    Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

  6. Materials Data on Sr(As2Rh3)2 (SG:187) by Materials Project

    SciTech Connect

    Kristin Persson

    2015-03-08

    Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations

  7. Diagnostics of hydromorphism in soils of autonomous positions on the Severo-Sos'vinsk Upland (Western Siberia)

    NASA Astrophysics Data System (ADS)

    Avetov, N. A.; Sopova, E. O.; Golovleva, Yu. A.; Kiryushin, A. V.; Krasilnikov, P. V.

    2014-11-01

    The complex studies of hydromorphism features in taiga weakly differentiated soils using morphological (color), chemical (iron content in different extracts, indicators of reducing conditions (IRIS)), and geobotanic (using the Ramenskii scale) methods have led to ambiguous conclusions. In all the soils, surface gleying was manifested. According to the results obtained by different methods, the maximum reduction processes were related to either the sublitter or the next deeper horizon. The Schwertmann coefficient, the criterion of Bodegom, and the Ramenskii scale indicated an increase of hydromorphism in the soils studied in the following sequence: the lower part of the ridge slopes drained by the small gullies < the middle part of the slopes < the flat tops of the ridges < the depression between the ridges. The morphological diagnostics of gleying proved to be a less sensitive method, which can recognize only the most contrasting hydromorphic soils. The lower horizons in some taiga soils have a bluish gray color probably not related to the recent soil hydromorphism.

  8. Retiring the Short-Run Aggregate Supply Curve

    ERIC Educational Resources Information Center

    Elwood, S. Kirk

    2010-01-01

    The author argues that the aggregate demand/aggregate supply (AD/AS) model is significantly improved--although certainly not perfected--by trimming it of the short-run aggregate supply (SRAS) curve. Problems with the SRAS curve are shown first for the AD/AS model that casts the AD curve as identifying the equilibrium level of output associated…

  9. Reducing time delay in the thrombolysis of myocardial infarction: an internal quality improvement project. ARIAM Project Group. Analisis del Retraso en Infarto Agudo de Miocardio.

    PubMed

    Saturno, P J; Felices, F; Segura, J; Vera, A; Rodriguez, J J

    2000-01-01

    The objectives of this study were to improve thrombolytic therapy in acute myocardial infarction by reducing the "door-to-needle" time in a 285-bed university hospital in Spain. A quality management approach was used involving all the relevant staff. Target standard was set at 35 minutes. Baseline data, intervention effect, and continuous monitoring were analyzed using x control charts. Analysis of baseline data showed a wide out-of-control variation and 72 minutes' average delay. Cause analysis revealed organizational and clinical problems that were subjected to intervention. Postintervention data showed a stable process, with an average of 30 minutes. Continuous monitoring showed further improvement in average time and predictable variation. The template of the current control chart has an average of 26 minutes. Quality management methods, particularly staff involvement in problem analysis and intervention design, and the use of control charts were useful to understand, solve, and continuously monitor an important clinical problem whose existence was evident only after it was measured. PMID:10872258

  10. Managing Performance in the System of Support: Rubric with 52 Indicators, Explanations, and Exemplars

    ERIC Educational Resources Information Center

    Hanes, Susan; Kerins, Thomas; Perlman, Carole; Redding, Sam; Ross, Steven

    2013-01-01

    The Building State Capacity and Productivity (BSCP) Center released a report outlining a process for state education agencies (SEAs) to evaluate and improve their System of Recognition, Accountability, and Support (SRAS). The federal government now sets high expectations for state and local use of federal dollars while allowing greater state…

  11. Crystallographic Orientation Determination of Hexagonal Structure Crystals by Laser Ultrasonic Technique

    NASA Astrophysics Data System (ADS)

    Li, W.; Coulson, J.; Marrow, P.; Smith, R. J.; Lainé, S. J.; Clark, M.; Sharples, S. D.

    2016-01-01

    Spatially resolved acoustic spectroscopy (SRAS) is a laser ultrasonic technique that shows qualitative contrast between grains of different orientation, illustrating the sensitivity of acoustic waves to the material structure. The technique has been improved significantly on determining the full orientation of multigrain cubic metals, by comparing the measured surface acoustic wave (SAW) velocity to a pre-calculated model. In this paper we demonstrate the ability of this technique to determine the orientation of hexagonal structure crystals, such as magnesium and titanium based alloys. Because of the isotropy of the SAW velocity on the basal plane (0001) of hexagonal crystals, the slowness surface is shown as a circle. As the plane moves from (0001) towards (112¯0) or towards (101¯0), the slowness surface gradually turns into an oval. These acoustic properties increase the difficulty in orientation determination. The orientation results of a grade 1 commercially pure titanium by SRAS is presented, with comparison with electron backscattered diffraction (EBSD) results. Due to the nature of SAWs on hexagonal structure crystals, only the results of Euler angles 1 and 2 are discussed. The error between SRAS and EBSD is also investigated.

  12. Primary angioplasty vs. fibrinolysis in very old patients with acute myocardial infarction: TRIANA (TRatamiento del Infarto Agudo de miocardio eN Ancianos) randomized trial and pooled analysis with previous studies

    PubMed Central

    Bueno, Héctor; Betriu, Amadeo; Heras, Magda; Alonso, Joaquín J.; Cequier, Angel; García, Eulogio J.; López-Sendón, José L.; Macaya, Carlos; Hernández-Antolín, Rosana; Bueno, Héctor; Hernández-Antolín, Rosana; Alonso, Joaquín J.; Betriu, Amadeo; Cequier, Angel; García, Eulogio J.; Heras, Magda; López-Sendón, José L.; Macaya, Carlos; Azpitarte, José; Sanz, Ginés; Chamorro, Angel; López-Palop, Ramón; Sionis, Alex; Arós, Fernando; García-Fernández, Eulogio; Rubio, Rafael; Hernández, Felipe; Tascón, Juan Carlos; Moreu, José; Betriu, Amadeu; Heras, Magda; Hernández-Antolín, Rosana; Fernández-Ortiz, Antonio; Morís, César; de Posada, Ignacio Sánchez; Cequier, Ángel; Esplugas, Enrique; Melgares, Rafael; Bosa, Francisco; García-González, Martín Jesús; Lezáun, Román; Carmona, José Ramón; Vázquez, José Manuel; Castro-Beiras, Alfonso; Picart, Joan García; de Rozas, José Domínguez; Fernández, José Díaz; Vázquez, Felipe Fernández; Alonso, Norberto; Zueco, José Javier; San José, José María; San Román, Alberto; Hernández, Carolina; García, José María Hernández; Alcántara, Ángel García; Bethencourt, Armando; Fiol, Miquel; Mancisidor, Xabier; Mancisidor, Xabier; Ruiz, Rafael; Hidalgo, Rafael; Sobrino, Nicolás; Maqueda, Isidoro González; Torres, Alfonso; Arós, Fernando; Amaro, Antonio; Jaquet, Michel

    2011-01-01

    Aims To compare primary percutaneous coronary intervention (pPCI) and fibrinolysis in very old patients with ST-segment elevation myocardial infarction (STEMI), in whom head-to-head comparisons between both strategies are scarce. Methods and results Patients ≥75 years old with STEMI <6 h were randomized to pPCI or fibrinolysis. The primary endpoint was a composite of all-cause mortality, re-infarction, or disabling stroke at 30 days. The trial was prematurely stopped due to slow recruitment after enroling 266 patients (134 allocated to pPCI and 132 to fibrinolysis). Both groups were well balanced in baseline characteristics. Mean age was 81 years. The primary endpoint was reached in 25 patients in the pPCI group (18.9%) and 34 (25.4%) in the fibrinolysis arm [odds ratio (OR), 0.69; 95% confidence interval (CI) 0.38–1.23; P = 0.21]. Similarly, non-significant reductions were found in death (13.6 vs. 17.2%, P = 0.43), re-infarction (5.3 vs. 8.2%, P = 0.35), or disabling stroke (0.8 vs. 3.0%, P = 0.18). Recurrent ischaemia was less common in pPCI-treated patients (0.8 vs. 9.7%, P< 0.001). No differences were found in major bleeds. A pooled analysis with the two previous reperfusion trials performed in older patients showed an advantage of pPCI over fibrinolysis in reducing death, re-infarction, or stroke at 30 days (OR, 0.64; 95% CI 0.45–0.91). Conclusion Primary PCI seems to be the best reperfusion therapy for STEMI even for the oldest patients. Early contemporary fibrinolytic therapy may be a safe alternative to pPCI in the elderly when this is not available. Clinicaltrials.gov # NCT00257309. PMID:20971744

  13. Chemical Contamination of Green Turtle (Chelonia mydas) Eggs in Peninsular Malaysia: Implications for Conservation and Public Health

    PubMed Central

    van de Merwe, Jason P.; Hodge, Mary; Olszowy, Henry A.; Whittier, Joan M.; Ibrahim, Kamarruddin; Lee, Shing Y.

    2009-01-01

    Background Persistent organic pollutants (POPs)—such as organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs)—and heavy metals have been reported in sea turtles at various stages of their life cycle. These chemicals can disrupt development and function of wildlife. Furthermore, in areas such as Peninsular Malaysia, where the human consumption of sea turtle eggs is prevalent, egg contamination may also have public health implications. Objective In the present study we investigated conservation and human health risks associated with the chemical contamination of green turtle (Chelonia mydas) eggs in Peninsular Malaysia. Methods Fifty-five C. mydas eggs were collected from markets in Peninsular Malaysia and analyzed for POPs and heavy metals. We conducted screening risk assessments (SRAs) and calculated the percent of acceptable daily intake (ADI) for POPs and metals to assess conservation and human health risks associated with egg contamination. Results C. mydas eggs were available in 9 of the 33 markets visited. These eggs came from seven nesting areas from as far away as Borneo Malaysia. SRAs indicated a significant risk to embryonic development associated with the observed arsenic concentrations. Furthermore, the concentrations of coplanar PCBs represented 3 300 times the ADI values set by the World Health Organization. Conclusions The concentrations of POPs and heavy metals reported in C. mydas eggs from markets in Peninsular Malaysia pose considerable risks to sea turtle conservation and human health. PMID:19750104

  14. Energy Dissipation and Defect Generation for Nanocrystalline Silicon Carbide

    SciTech Connect

    Gao, Fei; Chen, Dong; Hu, Wangyu; Weber, William J.

    2010-05-05

    Large-scale molecular dynamics simulations have been employed to study defect generation and primary damage state in nano crystalline (NC) SiC of average grain diameters from 5 to 21 nm. Primary knock-on atom (PKA) kinetic energies of 10 keV are simulated, and cascade structures in NC SiC with a grain size smaller than 12 nm are generally different from those generated in single crystalline SiC. It is found that the local stresses near the grain boundaries (GBs) strongly affect the behavior of the PKA and secondary recoil atoms (SRAs), and the GBs act as sinks for deposition of kinetic energy. A striking feature is that the PKA and SRAs preferentially deposit energy along the GBs for grains with average size less 12 nm, which results in atomic displacements primarily within the GBs; whereas for larger grain sizes, most defects are produced within the grains. There exists a crossover in defect production, which is manifested in switching from grain boundary damage to grain damage. The most common defects created in NC SiC are antisite defects, following by vacancies and interstitials, in contrast to those produced in a single crystalline SiC, where the dominate defects are Frenkel pairs. Defect production efficiency increases with increasing the grain size, with a typical value of 0.18 for small grains and rising to 0.5 for larger grains.

  15. Energy dissipation and defect generation in nanocrystalline silicon carbide

    SciTech Connect

    Gao, F.; Weber, W. J.; Chen, D.; Hu Wangyu

    2010-05-01

    Large-scale molecular-dynamics simulations have been employed to study defect generation and primary damage state in nanocrystalline (NC) SiC of average grain diameters from 5 to 21 nm. Primary knock-on atom (PKA) kinetic energies of 10 keV are simulated and cascade structures in NC SiC with a grain size smaller than 12 nm are generally different from those generated in single-crystalline SiC. It is found that the local stresses near the grain boundaries (GBs) strongly affect the behavior of the PKA and secondary recoil atoms (SRAs), and the GBs act as sinks for deposition of kinetic energy. A striking feature is that the PKA and SRAs preferentially deposit energy along the GBs for grains with average size less 12 nm, which results in atomic displacements primarily within the GBs; whereas for larger grain sizes, most defects are produced within the grains. The defect production within gains generally increases with increasing grain size, which is manifested in switching from grain boundary damage to grain damage. The most common defects created in NC SiC are antisite defects, following by vacancies and interstitials, in contrast to those produced in a single-crystalline SiC, where the dominate defects are Frenkel pairs. Defect production efficiency increases with increasing grain size, with a typical value of 0.18 for small grains and rising to 0.5 for larger grains.

  16. The origin of early age expansions induced in cementitious materials containing shrinkage reducing admixtures

    SciTech Connect

    Sant, Gaurav; Lothenbach, Barbara; Juilland, Patrick; Le Saout, Gwenn; Weiss, Jason; Scrivener, Karen

    2011-03-15

    Studies on the early-age shrinkage behavior of cement pastes, mortars, and concretes containing shrinkage reducing admixtures (SRAs) have indicated these mixtures frequently exhibit an expansion shortly after setting. While the magnitude of the expansion has been noted to be a function of the chemistry of the cement and the admixture dosage; the cause of the expansion is not clearly understood. This investigation uses measurements of autogenous deformation, X-ray diffraction, pore solution analysis, thermogravimetry, and scanning electron microscopy to study the early-age properties and describe the mechanism of the expansion in OPC pastes made with and without SRA. The composition of the pore solution indicates that the presence of the SRA increases the portlandite oversaturation level in solution which can result in higher crystallization stresses which could lead to an expansion. This observation is supported by deformation calculations for the systems examined.

  17. Raman Amplification and Tunable Pulse Delays in Silicon Waveguides

    SciTech Connect

    Rukhlenko, Ivan D.; Premaratne, Malin; Garanovich, Ivan L.; Sukhorukov, Andrey A.; Agrawal, Govind P.

    2010-10-07

    The nonlinear process of stimulated Raman scattering is important for silicon photonics as it enables optical amplification and lasing. However, generally employed numerical approaches provide very little insight into the contribution of different silicon Raman amplifier (SRA) parameters. In this paper, we solve the coupled pump-signal equations analytically and derive an exact formula for the envelope of a signal pulse when picosecond optical pulses are amplified inside a SRA pumped by a continuous-wave laser beam. Our solution is valid for an arbitrary pulse shape and fully accounts for the Raman gain-dispersion effects, including temporal broadening and group-velocity reduction. Our results are useful for optimizing the performance of SRAs and for engineering controllable signal delays.

  18. Thyroid iodide compartments and their implication in the rat thyroid iodine organification

    SciTech Connect

    Bastiani, P.; Simon, C.

    1982-05-01

    To estimate the relative participation of transported and intrathyroidally generated iodide (internal iodide) in the iodination of newly synthesized and preexisting thyroglobulin (Tg) in the rat thyroid, the specific radioactivities (SRAs) of thyroid iodide, Tg, lysosomal iodine, and plasma hormones were followed for 92 h after radioactive iodide injection in intact or hypophysectomized rats. In control rats, the SRA of Tg and lysosomal iodine reached a maximum at 12 h. However, the SRA of lysosomal iodide was always smaller than that of Tg. In contrast, the SRA of hormonal iodide attained a maximum at 48 h. Thus, newly labeled iodine is endocytosed and mixed inside the lysosomes with older previously iodinated molecules; hormone secretion is mainly due to old labeled iodine (i.e. iodine with a high SRA from 48-96 h). These results are consistent with the presence of least two Tg compartments, with different turnover rates and hormone contents. On the other hand, in hypophysectomized rats, the SRA of Tg, lysosomes, and hormones showed only one maximum, at 24 h. Furthermore, the SRAs of Tg and lysosomes were similar at each time interval. It is inferred that in such rats, the old labeled iodine compartment is strongly reduced, and that inside the lysosomes, newly labeled iodine is predominant. Since in hypophysectomized rats, the recycling of iodide is abolished, it is concluded that in normal rats: 1) transported iodide is organified mainly by direct iodination of newly synthesized Tg, independently of TSH, and 2) internal iodide is organified mainly by delayed iodination of preexisting Tg, this process being TSH dependent.

  19. Fundamental investigations related to the mitigation of volume changes in cement-based materials at early ages

    NASA Astrophysics Data System (ADS)

    Sant, Gaurav Niteen

    The increased use of high-performance, low water-to-cement (w/c) ratio concretes has led to increased occurrences of early-age shrinkage cracking in civil engineering structures. To reduce the magnitude of early-age shrinkage and the potential for cracking, mitigation strategies using shrinkage reducing admixtures (SRAs), saturated lightweight aggregates, expansive cements and extended moist curing durations in construction have been recommended. However, to appropriately utilize these strategies, it is important to have a complete understanding of the driving forces of early-age volume change and how these methods work from a materials perspective to reduce shrinkage. This dissertation uses a first-principles approach to understand the mechanism of shrinkage reducing admixtures (SRAs) to generate an expansion and mitigate shrinkage at early-ages, quantify the influence of a CaO-based expansive additive in reducing unrestrained shrinkage, residual stress development and the cracking potential at early-ages and quantify the influence of shrinkage reducing admixtures (SRAs) and cement hydration (pore structure refinement) on the reduction induced in the fluid transport properties of the material. The effects of shrinkage reducing admixtures (SRAs) are described in terms of inducing autogenous expansions in cement pastes at early ages. An evaluation comprising measurements of autogenous deformation, x-ray diffraction (Rietveld analysis), pore solution and thermogravimetric analysis and electron microscopy is performed to understand the chemical nature and physical effects of the expansion. Thermodynamic calculations performed on the measured liquid-phase compositions indicate the SRA produces elevated Portlandite super-saturations in the pore solution which results in crystallization stress driven expansions. The thermodynamic calculations are supported by deformation measurements performed on cement pastes mixed in solutions saturated with Portlandite or containing

  20. Paleotemperature regime studies of the Barents Sea sediments through spontaneous fission-track analysis

    SciTech Connect

    Il`chenko, V.L.

    1995-09-01

    The results obtained are compared to earlier data on vitrinite reflectance and the catagenetic alteration grade of disseminated organic matter studied in samples from the same boreholes and stratigraphic intervals. Accessory apatite from terricrenous sediments is usable as a geothermometer of higher sensitivity than that based on epigenetic alterations of organic matter. The fission-track analysis data on the paleothermal history of terrigenous sediments from the South Barents Depression are presented. Apatite from six offshore boreholes in the South Barents shelf (Severo-Guliaev, Kurentsov, Murman, Severo-Kil`din, Shtokman, and Ludlov fields) is studied. Paleotemperature values lying within or beyond the upper limit of the oil-productive thermal interval are considered important factors stimulating the generation of hydrocarbons.

  1. Kidney Stones: What You Need to Know

    MedlinePlus

    ... el riñón? Una piedra en el riñón es un pedazo de material sólido que se forma en un riñón cuando hay altos niveles de ciertas sustancias ... al orinar • ve sangre en la orina • siente un dolor agudo en la espalda o la parte ...

  2. Sensors of Infection: Viral Nucleic Acid PRRs in Fish

    PubMed Central

    Poynter, Sarah; Lisser, Graeme; Monjo, Andrea; DeWitte-Orr, Stephanie

    2015-01-01

    Viruses produce nucleic acids during their replication, either during genomic replication or transcription. These nucleic acids are present in the cytoplasm or endosome of an infected cell, or in the extracellular space to be sensed by neighboring cells during lytic infections. Cells have mechanisms of sensing virus-generated nucleic acids; these nucleic acids act as flags to the cell, indicating an infection requiring defense mechanisms. The viral nucleic acids are called pathogen-associated molecular patterns (PAMPs) and the sensors that bind them are called pattern recognition receptors (PRRs). This review article focuses on the most recent findings regarding nucleic acids PRRs in fish, including: Toll-like receptors (TLRs), RIG-I-like receptors (RLRs), cytoplasmic DNA sensors (CDSs) and class A scavenger receptors (SR-As). It also discusses what is currently known of the downstream signaling molecules for each PRR family and the resulting antiviral response, either type I interferons (IFNs) or pro-inflammatory cytokine production. The review highlights what is known but also defines what still requires elucidation in this economically important animal. Understanding innate immune systems to virus infections will aid in the development of better antiviral therapies and vaccines for the future. PMID:26184332

  3. Human hair analysis in relation to similar environmental and occupational exposure.

    PubMed

    Szynkowska, Małgorzata Iwona; Marcinek, Marta; Pawlaczyk, Aleksandra; Albińska, Jadwiga

    2015-09-01

    The aim of this work was to assess the influence of various factors on the elemental composition of the investigated hair samples. The studied population consisted of students of Faculty of Chemistry at Lodz University of Technology and included 95 subjects. The following elements: Co, Cr, Cu, Li, Sr, Pb were determined by inductively coupled plasma time-of-flight mass spectrometry ICP-TOF-MS. The obtained results were elaborated using Statistica ver. 10.0 software. Statistically significant differences were observed for the content of Cr, Li, Pb and Sr as the impact of sex, and Sr-as the effect of cosmetic treatment. Based on the calculated Spearman correlation coefficients, a statistically significant correlation between the concentration of pairs of metals were found for Pb=f(Co, Cr, Cu); Sr=f(Cu); Li=f(Cr), Cr=f(Li, Pb), Co=f(Pb) and Cu=f(Pb, Sr). A statistically negative correlation was obtained for Sr-Li. In the population two groups were distinguished: males and females; smokers and non-smokers. PMID:26247617

  4. Evolutionary Aspects of the S-Related Genes of the Brassica Self-Incompatibility System: Synonymous and Nonsynonymous Base Substitutions

    PubMed Central

    Hinata, K.; Watanabe, M.; Yamakawa, S.; Satta, Y.; Isogai, A.

    1995-01-01

    In the Brassicaceae, self-vs. nonself-recognition in self-incompatibility is controlled by sporophytic S-alleles. Haplotypes specifying both SRK (S-receptor kinase) and SLG (S-locus glycoprotein) are considered to play an important role in the recognition reactions. We compared the nucleotide sequences of SRK(9)(Bc) and SRK(6)(Bo). The number of nonsynonymous substitutions per site (P(n)) was lower, constrained, in the kinase than the receptor domain, while the numbers of synonymous substitutions (P(s)) in the two domains were largely comparable. Pairwise values for P(s) and P(n) were calculated among 17 operational taxonomic units, including eight SLGs, the receptor domains of two SRKs, four SRAs (S-related A) and three SRBs (S-related B), which have high homologies with each other. The values of P(s) and P(n) of SLG were mostly comparable to those of the receptor domain of SRK. Dendrograms constructed on the basis of P(n) and P(s) indicated that SRA differentiated first, followed by SRB. The differentiation of SLG alleles is one of prerequisite factors for the establishment of self-incompatibility, and the allelic differentiation has occurred more than tens of million years ago. PMID:7672580

  5. Sensor Network Demonstration for In Situ Decommissioning - 13332

    SciTech Connect

    Lagos, L.; Varona, J.; Awwad, A.; Rivera, J.; McGill, J.

    2013-07-01

    individual sensors would be immobilized during the grout pouring activities, a set of nine sensor racks were designed. The 270 sensors provided by Idaho National Laboratory (INL), Mississippi State University (MSU), University of Houston (UH), and University of South Carolina (USC) were secured to these racks based on predetermined locations. Once sensor racks were installed inside the test cube, connected and debugged, approximately 32 cubic yards of special grout material was used to entomb the sensors. MSU provided and demonstrated four types of fiber loop ring-down (FLR) sensors for detection of water, temperature, cracks, and movement of fluids. INL provided and demonstrated time differenced 3D electrical resistivity tomography (ERT), advanced tensiometers for moisture content, and thermocouples for temperature measurements. University of Houston provided smart aggregate (SA) sensors, which detect crack severity and water presence. An additional UH sensor system demonstrated was a Fiber Bragg Grating (FBG) fiber optic system measuring strain, presence of water, and temperature. USC provided a system which measured acoustic emissions during cracking, as well as temperature and pH sensors. All systems were connected to a Sensor Remote Access System (SRAS) data networking and collection system designed, developed and provided by FIU. The purpose of SRAS was to collect and allow download of the raw sensor data from all the sensor system, as well as allow upload of the processed data and any analysis reports and graphs. All this information was made available to the research teams via the Deactivation and Decommissioning Knowledge Management and Information Tool (D and D KM-IT). As a current research effort, FIU is performing an energy analysis, and transferring several sensor systems to a Photovoltaic (PV) System to continuously monitor energy consumption parameters and overall power demands. Also, One final component of this research is focusing on developing an integrated

  6. A comparison of the velocity parameters of SiO V = 1, J = 1 − 0, and J = 2 − 1 maser emission in semiregular variables

    SciTech Connect

    McIntosh, Gordon; Indermuehle, Balthasar E-mail: balt.indermuehle@csiro.au

    2015-03-01

    We have determined and compared the SiO maser velocity parameters of semiregular variables in the v = 1, J = 1 − 0 (J10{sup 1}) and the v = 1, J = 2 − 1 (J21) transitions. Fourteen sources in the Mopra SiO Maser Catalogue are classified as semiregular variables of types SR, SRa, SRb, or SRc. (L2 Puppis, an SRa star with an unusual SiO maser spectrum, has been analyzed individually.) We have previously presented the overall and phase dependent velocity parameters of SiO masers associated with long period variables (LPVs) of well-established periods and maxima. A comparison of the velocity centroid (VC) difference, VC21–VC10, shows mixed results for the variable types. Some differences are negative and some positive. The SRc difference is negative, large, and relatively stable. The SRb difference has the widest distribution. The velocity ranges (VRs) of the maser emission have been compared using arithmetic averages, Gaussian fits to the distributions, and Weibull fits to the distributions. For LPVs, SRs, SRas, and SRcs the VR10 is one to a few km s{sup −1} greater than the VR21. SRcs have the largest VRs by a factor of two or three indicating the greater range over which the conditions necessary for masers to originate exist in these supergiant stars. SRbs are the only classification of semiregular variable in which the VR21 exceeds the VR10. The larger VR21 compared to VR10 for SRbs appears in all comparisons. The difference in the SRb SiO maser velocity parameters may be due to a difference in the oscillation mechanism of the star. The suggested overtone oscillations of SRbs may affect the circumstellar cloud dynamics. Little theoretical work has specifically addressed the masers in semiregular variables. Qualitative comparisons of the data with the existing models of the SiO masers in LPVs are made.

  7. Paleozoic crudes of Tomsk province

    SciTech Connect

    Smol'yaninova, N.M.; Mashukova, Z.I.; Nemirovskaya, G.V.

    1983-01-01

    The Paleozoic crudes typically have low densities at 20/sup 0/C, low contents of resins, high viscosities at 20/sup 0/C, rather high solid points, and high contents of solid paraffins. The Paleozoic crudes are in no way inferior in quality to the Mesozoic crudes of Tomsk province, and are even better in some respects (yields of high-V.I. and medium-V.I. oils). They can be processed with either a fuel/lube or petrochemical refining scheme. Finds that the crudes from the Ostaninsk and SeveroOstaninsk fields, in terms of their paraffin and sulfur contents and other indexes, are similar to the Jurassic crudes of the Zhetybai field on the Mangyshlak peninsula. These 2 crudes and the Chkalovsk crude, even though the high wax contents offer problems in production and transportation, can serve as good raw materials for fuel and oil production, and also for the manufacture of liquid and solid paraffins.

  8. Lagrangian Descriptors: A Method for Revealing Phase Space Structures of General Time Dependent Dynamical Systems

    NASA Astrophysics Data System (ADS)

    Mancho, Ana M.; Wiggins, Stephen; Curbelo, Jezabel; Mendoza, Carolina

    2013-11-01

    Lagrangian descriptors are a recent technique which reveals geometrical structures in phase space and which are valid for aperiodically time dependent dynamical systems. We discuss a general methodology for constructing them and we discuss a ``heuristic argument'' that explains why this method is successful. We support this argument by explicit calculations on a benchmark problem. Several other benchmark examples are considered that allow us to assess the performance of Lagrangian descriptors with both finite time Lyapunov exponents (FTLEs) and finite time averages of certain components of the vector field (``time averages''). In all cases Lagrangian descriptors are shown to be both more accurate and computationally efficient than these methods. We thank CESGA for computing facilities. This research was supported by MINECO grants: MTM2011-26696, I-Math C3-0104, ICMAT Severo Ochoa project SEV-2011-0087, and CSIC grant OCEANTECH. SW acknowledges the support of the ONR (Grant No. N00014-01-1-0769).

  9. Relation of Lagragian structures and drifter dynamics in the Gulf of Mexico

    NASA Astrophysics Data System (ADS)

    Mendoza, Carolina; Mancho, Ana Maria; Wiggins, Stephen

    2013-11-01

    We use a Lagrangian descriptor (the so called function M) which measures the length of particle trajectories on the ocean surface over a given interval of time. With this tool we identify the Lagrangian skeleton of the flow and compare it on three datasets over the Gulf of Mexico during the year 2010. The satellite altimetry data used come from AVISO and simulations from HYCOM GOMl0.04 experiments 30.1 and 31.0. We contrast the Lagrangian structure and transport using the evolution of several surface drifters. We show that the agreement in relevant cases between Lagrangian structures and dynamics of drifters depends on the quality of the data on the studied area. We acknowledge to the grants: Becas de Movilidad de Caja Madrid 2011, MTM2011-26696, ILINK-0145, ONR Grant Number N00014-01-1-0769 and ICMAT Severo Ochoa SEV-2011-0087.

  10. Constituent Quarks and Gluons, Polyakov loop and the Hadron Resonance Gas Model ***

    NASA Astrophysics Data System (ADS)

    Megías, E.; Ruiz Arriola, E.; Salcedo, L. L.

    2014-03-01

    Based on first principle QCD arguments, it has been argued in [1] that the vacuum expectation value of the Polyakov loop can be represented in the hadron resonance gas model. We study this within the Polyakov-constituent quark model by implementing the quantum and local nature of the Polyakov loop [2, 3]. The existence of exotic states in the spectrum is discussed. Presented by E. Megías at the International Nuclear Physics Conference INPC 2013, 2-7 June 2013, Firenze, Italy.Supported by Plan Nacional de Altas Energías (FPA2011-25948), DGI (FIS2011-24149), Junta de Andalucía grant FQM-225, Spanish Consolider-Ingenio 2010 Programme CPAN (CSD2007-00042), Spanish MINECO's Centro de Excelencia Severo Ochoa Program grant SEV-2012-0234, and the Juan de la Cierva Program.

  11. Esquizofrenia y trastorno en el consumo de sustancias: prevalencia y characterísticas sociodemográficas en la población Latina

    PubMed Central

    Jiménez-Castro, Lorena; Raventós-Vorst, Henriette; Escamilla, Michael

    2012-01-01

    El interés por comprender la co-morbilidad de la esquizofrenia y el trastorno en el uso de sustancias, ha aumentado debido al incremento de este diagnóstico, a los efectos negativos observados en el sujeto y a los costos en los servicios de salud. Este trastorno dual puede tener efectos dramáticos en el curso clínico del trastorno psicótico tales como: mayores recaídas, re-hospitalizaciones, síntomas más severos, no adherencia al tratamiento antipsicótico, cambios marcados del humor, aumento en el grado de hostilidad e ideación suicida, así como alteraciones en otras áreas del funcionamiento incluyendo violencia, victimización, indigencia y problemas legales. La literatura proveniente en particular de Estados Unidos y Europa sugiere que el rango de prevalencia para este diagnóstico puede oscilar entre el 10% hasta el 70%. En este estudio, revisamos la prevalencia del diagnóstico dual de esquizofrenia y trastorno en el uso sustancias, así como sus características sociodemográficas, con base en la literatura disponible alrededor del mundo dando énfasis en la poblacion latina. A pesar de que este diagnóstico es ampliamente aceptado, se conoce poco sobre su prevalencia en la población latina, sobre los factores ambientales, demográficos, clínicos y otras características de estos individuos. Un mejor conocimiento sobre este diagnóstico permitiría mejorar los métodos para la detección y adecuada valoración del trastorno en el uso de sustancias en personas con trastornos metales severos como la esquizofrenia. PMID:21404151

  12. Mineral replacement reactions and element mobilization

    NASA Astrophysics Data System (ADS)

    Putnis, Christine V.; Ruiz-Agudo, Encarnacion; King, Helen E.; Hövelmann, Jörn; Renard, François

    2016-04-01

    When a mineral is out of equilibrium with an aqueous fluid, reactions will take place in an attempt to reach a new equilibrium. Commonly in the Earth dissolution at a mineral-fluid interface initiates a coupled reaction involving dissolution and precipitation (Ruiz-Agudo et al., 2014). This is a ubiquitous reaction during such processes as metamorphism, metasomatism and weathering. When rock-forming minerals such as feldspars, olivine, pyroxenes are in contact with aqueous fluids (typically NaCl-rich) resultant new phases are formed and elements present in the parent mineral are released to the fluid and therefore mobilized for transport elsewhere. This has been shown in a number of systems such as the albitisation of feldspars (Hövelmann et al., 2010) when a Ca-bearing plagioclase is replaced by albite (NaAlSi3O8). However during this reaction not only is Ca released to the fluid but most other minor elements, such as Mg, Pb, rare earth elements amongst others, are almost totally mobilized and removed in solution. This interface-coupled dissolution-precipitation reaction has many implications for the redistributon of elements in the crust of the Earth. It is also of note that albitisation occurs often in areas of high mineralization, such as in the Curnamona Province in S. Australia (Au-Cu and Ag-Pb-Zn deposits) and the Bamble District of S. Norway. Secondly atomic force microscopy (AFM) has been used to image these reactions at a nanoscale, especially at the calcite-fluid interface, such as the formation of apatite from phosphate-bearing solutions, and the sequestration of toxic elements, eg., Se and As. References Ruiz-Agudo E., Putnis C.V., Putnis A. (2014) Coupled dissolution and precipitation at mineral-fluid interfaces. Chemical Geology, 383, 132-146. Putnis C.V. and Ruiz-Agudo E. (2013) The mineral-water interface: where minerals react with the environment. Elements, 9, 177-182. Hövelmann J., Putnis A., Geisler T., Schmidt B.C., Golla-Schindler U. (2009

  13. [In Process Citation].

    PubMed

    Daponte Codina, A; Bolivar Muñoz, J; Sánchez-Cantalejo, E; Mateo-Rodríguez, I; Babio, G; Romo-Avilés, N; Rosell-Ortiz, F; Grupo de Estudio de Género Y Enfermedades Cardiovasculares, G

    2016-01-01

     RESUMEN              Fundamento. Identificar factores asociados a la demora prehospitalaria en personas que han tenido un síndrome coronario agudo             Método. Se estudiaron mediante encuesta pacientes ingresados por síndrome coronario agudo en los 33 hospitales públicos andaluces, obteniéndose información sobre diferentes tipos de variables: socio-demográficas, contextuales, clínicas, percepción, actuaciones, y transporte. Se aplicaron modelos de regresión logística multivariante para calcular las odds ratio para la demora.             Resultados. De los 1.416 pacientes en total, más de la mitad tuvieron una demora superior a la hora. Se asocia a la distancia al hospital y al medio de transporte: cuando el evento ocurre en la misma ciudad del hospital, utilizar medios propios aumenta la demora, odds ratio= 1,51 (1,02-2,23);  si la distancia es entre 1-25 kilómetros, no hay una diferencia entre medios propios y ambulancia, odds ratio = 1,41 y odds ratio = 1,43 respectivamente; y cuando supera los25 kilómetros la ambulancia implica mayor demora, odds ratio = 3,13 y odds ratio = 2,20 respectivamente. Además, la sintomatología típica reduce la demora entre los hombres, pero la aumenta entre las mujeres. Asimismo, no darle importancia, esperar a la resolución de los síntomas, buscar atención sanitaria diferente a urgencias hospitalarias o al 061, tener antecedentes, encontrarse fuera de la vivienda habitual, y tener ingresos menores de 1.500 euros aumentan la demora. Tener síntomas respiratorios la reduce.             Conclusiones. La demora prehospitalaria no se ajusta a las recomendaciones sanitarias, asociándose al  entorno físico y social, a factores clínicos, y de percepción y actitudinales de los sujetos.              Palabras clave. Síndrome coronario agudo. Demora prehospitalaria. Género. Servicios de emergencias sanitarias. Desigualdades. PMID:27125609

  14. A non-classical view of the modulation of mineral precipitation by organic additives

    NASA Astrophysics Data System (ADS)

    Ruiz-Agudo, Encarnacion; Ruiz-Agudo, Cristina; Burgos-Cara, Alejandro; Putnis, Christine; Rodriguez-Navarro, Carlos; Putnis, Andrew

    2016-04-01

    Questions persist on the mechanisms of crystallization of sparingly soluble minerals such as calcium carbonate, calcium oxalate or barium sulphate. Compared to CaCO3, the mechanisms of nucleation and growth in the CaC2O4-H2O or BaSO4-H2O systems have received less attention. These phases are important due to their relevance as biominerals and/or unwanted mineral deposits in technological applications. Growing evidence suggests that sparingly soluble salts form by non-classical nucleation and growth pathways, where pre-nucleation ion associates and amorphous (solid or liquid) precursor phase(s) play a critical role (e.g. Rodríguez-Navarro et al. (2015), Ruiz-Agudo et al. (2015)). Indeed the identification of pre-nucleation species in these systems and their strong interactions with organic compounds (Verch et al. 2011) raises the possibility that the control of organics on biomineralization may begin even earlier than previously thought. A sound knowledge of the physical mechanisms by which acidic macromolecules affect nucleation and early growth may offer general insights concerning the molecular control of biomineralization, as well as being critical for improving strategies to control unwanted mineral deposition or for the synthesis of biomimetic materials. Here we present investigations on the initial stages of the precipitation of these relevant minerals in organic-free solutions to identify the precipitation pathway and to look for any potential precursor phase(s) to the final, crystalline polymorph. As well, we explore the effects that several acidic organic compounds have on the different precipitation stages identified. We find that organic additives such as citric acid, polyacrilic acid or a commercial copolymer of maleic acid/allyl sulfonic acid with phosphonate groups can be active at modifying pre-nucleation stages (destabilizing of pre-nucleation species or hampering the aggregation and growth of pre-nucleation associates) and subsequently strongly

  15. Plate-like convection in fluids with temperature-dependent viscosity

    NASA Astrophysics Data System (ADS)

    Mancho, Ana M.; Curbelo, Jezabel

    2013-11-01

    The study of instabilities in fluids in which viscosity experiences a transition at a certain temperature range is of great interest for the understanding of planetary interiors, since this phenomena models the melting and solidification of a magma ocean and thus is suitable for representing a lithosphere over a convecting mantle. To this end, we study a 2D convection problem in which viscosity depends on temperature by abruptly changing its value by a factor 400 within a narrow temperature gap at which magma melts. We perform a study which combines bifurcation analysis and time dependent simulations. Solutions such as limit cycles are found that are fundamentally related to the presence of the O(2) symmetry. Sporadically during these cycles, through abrupt bursts, spontaneous plate-like behaviors that rapidly evolve towards a stagnant lid regime emerge. The plate-like evolution alternates motions towards either right or left, introducing temporary asymmetries on the convecting styles. Further time dependent regimes are described for different transition laws which are greatly influenced by the presence of the symmetry. We thank CESGA for computing facilities. This research is supported by the Spanish Ministry of Science under grant MTM2011-26696 and MINECO: ICMAT Severo Ochoa project SEV-2011-0087.

  16. Wanderings in Biochemistry

    PubMed Central

    Lengyel, Peter

    2014-01-01

    My Ph.D. thesis in the laboratory of Severo Ochoa at New York University School of Medicine in 1962 included the determination of the nucleotide compositions of codons specifying amino acids. The experiments were based on the use of random copolyribonucleotides (synthesized by polynucleotide phosphorylase) as messenger RNA in a cell-free protein-synthesizing system. At Yale University, where I joined the faculty, my co-workers and I first studied the mechanisms of protein synthesis. Thereafter, we explored the interferons (IFNs), which were discovered as antiviral defense agents but were revealed to be components of a highly complex multifunctional system. We isolated pure IFNs and characterized IFN-activated genes, the proteins they encode, and their functions. We concentrated on a cluster of IFN-activated genes, the p200 cluster, which arose by repeated gene duplications and which encodes a large family of highly multifunctional proteins. For example, the murine protein p204 can be activated in numerous tissues by distinct transcription factors. It modulates cell proliferation and the differentiation of a variety of tissues by binding to many proteins. p204 also inhibits the activities of wild-type Ras proteins and Ras oncoproteins. PMID:24867946

  17. RETOS EN LA INTERVENCIÓN CON ADOLESCENTES PUERTORRIQUEÑOS/AS QUE MANIFIESTAN COMPORTAMIENTO SUICIDA*

    PubMed Central

    Vélez, Yovanska Duarté; Dávila, Paloma Torres; Hernández, Samariz Laboy

    2015-01-01

    Presentamos un estudio de caso de una adolescente puertorriqueña con comportamiento suicida. Esta comenzó una Terapia Socio Cognitivo-Conductual para el Comportamiento Suicida (TSCC-CS) de tipo ambulatorio luego de una hospitalización por intento suicida. La TSCC-CS incorpora una perspectiva ecológica y de desarrollo a la terapia cognitivo-conductual. Inicialmente mostró baja autoestima y severos síntomas depresivos y de ansiedad. Al finalizar el tratamiento, manifestó un cambio significativo en su sintomatología clínica y evidenció una mejoría en sus destrezas de manejo. No presentó ideas suicidas durante meses previos, ni durante el seguimiento. El análisis de este caso permitió realizar cambios en el protocolo de tratamiento, particularmente en las sesiones de familia y de comunicación con el fin de aumentar la viabilidad del tratamiento. PMID:26702337

  18. Storage enhanced non-linearities in a cold Rydberg ensemble

    NASA Astrophysics Data System (ADS)

    Distante, Emanuele; Padron-Brito, Auxiliadora; Cristiani, Matteo; Paredes-Barato, David; de Riedmatten, Hugues

    2016-05-01

    The possibility to control the interaction between photons provided by highly nonlinear media is a key ingredient to the goal of quantum information processing using photons and a unique tool to study the dynamics of the many-body correlated system. To mediate this interaction, one can exploit electromagnetically induced transparency (EIT) to map the state of the photons into atomic coherence in the form of Rydberg dark-state polaritons. The combination of EIT with the nonlinear interaction between Rydberg atoms provides and effective interaction between photons. By measuring the dynamics of stored Rydberg polaritons, we experimentally demonstrate that storing a probe pulse as Rydberg polaritons strongly enhances the Rydberg mediated interaction compared to the slow-propagation case. We show that the process is characterized by two time scales. We measure a strong enhancement of the interaction at short time scales. By measuring the time-dependent coherence of the stored polariton, we also show that the long time scale dynamics is dominated by Rydberg induced dephasing of the multiparticle components of the state. Our results have a direct consequence in Rydberg quantum optics and enable the test of new theories of strongly interacting Rydberg systems. This work has been funded by: ERC starting Grant QuLIMA, MINECO, Severo Ochoa Grant, AUGAUR and the Europea Union's Horizon 2020.

  19. A Dynamical System Approach to the Surface Search of Debris from MH370

    NASA Astrophysics Data System (ADS)

    Mancho, Ana M.; Garcia-Garrido, V. J.; Wiggins, S.; Mendoza, C.

    2015-11-01

    The disappearance of Malaysia Airlines flight MH370 on the morning of the 8th of March 2014 is one of the great mysteries of our time. One relevant aspect of this mystery is that not a single piece of debris from the aircraft was found during the intensive surface search carried out in the months following the crash. Difficulties in the search efforts, due to the uncertainty in the plane's final impact point and the time passed since the accident, brought the question on how the debris was scattered in an always moving ocean, for which there were multiple datasets that do not uniquely determined its state. Our approach to this problem is based on dynamical systems tools that identify dynamic barriers and coherent structures governing transport. By combining different ocean data with these mathematical techniques, we are able to assess the spatio-temporal state of the ocean in the priority search area at the time of impact and the following weeks. Using this information we propose a revised search strategy by showing why one might not have expected to find debris in some large search areas targeted by the search services and determining regions where one might have expected impact debris to be located and that have not been subjected to any exploration. This research has been supported by MINECO under grants MTM2014-56392-R and ICMAT Severo Ochoa project SEV-2011-0087 and ONR grant No. N00014- 01-1-0769. Computational support from CESGA is acknowledged.

  20. Modelling direct radiative effect of mineral dust with the NMMB/BSC-CTM for dust outbreak events over the Mediterranean in summer 2012

    NASA Astrophysics Data System (ADS)

    Obiso, Vincezo; Jorba, Oriol; Basart, Sara; Baldasano, Jose M.; Nabat, Pierre

    2014-05-01

    Aerosols interact with the atmospheric system scattering and absorbing solar radiation, with a significant impact on atmospheric energy and hydrologic processes. Radiative forcing associated with these perturbations affects climate and meteorology. In this contribution, we analyse model results of the Direct Radiative Effect (DRE) of mineral dust over the western-Mediterranean during summer 2012. For that, the NMMB/BSC Chemical Transport Model (NMMB/BSC-CTM) is applied on a regional domain at 0.1º horizontal resolution. The NMMB/BSC-CTM is a new on-line chemical weather prediction system coupling atmospheric and chemistry processes. In the radiation module of the model mineral dust is treated as a radiatively active substance interacting both short and longwave radiation. The impact of the mineral dust outbreaks on meteorology is discussed by comparing model forecasts with atmospheric analysis and meteorological observations. The analysis focuses in the vertical structure of the atmosphere and the resulting surface meteorological conditions. The authors acknowledge the support from the grant SEV-2011-00067 of Severo Ochoa Program, awarded by the Spanish Government.

  1. Controlled rephasing of single spin-waves in a quantum memory based on cold atoms

    NASA Astrophysics Data System (ADS)

    Farrera, Pau; Albrecht, Boris; Heinze, Georg; Cristiani, Matteo; de Riedmatten, Hugues; Quantum Photonics With Solids; Atoms Team

    2015-05-01

    Quantum memories for light allow a reversible transfer of quantum information between photons and long lived matter quantum bits. In atomic ensembles, this information is commonly stored in the form of single collective spin excitations (spin-waves). In this work we demonstrate that we can actively control the dephasing of the spin-waves created in a quantum memory based on a cold Rb87 atomic ensemble. The control is provided by an external magnetic field gradient, which induces an inhomogeneous broadening of the atomic hyperfine levels. We show that acting on this gradient allows to control the dephasing of individual spin-waves and to induce later a rephasing. The spin-waves are then mapped into single photons, and we demonstrate experimentally that the active rephasing preserves the sub-Poissonian statistics of the retrieved photons. Finally we show that this rephasing control enables the creation and storage of multiple spin-waves in different temporal modes, which can be selectively readout. This is an important step towards the implementation of a functional temporally multiplexed quantum memory for quantum repeaters. We acknowledge support from the ERC starting grant, the Spanish Ministry of Economy and Competitiveness, the Fondo Europeo de Desarrollo Regional, and the International PhD- fellowship program ``la Caixa''-Severo Ochoa @ICFO.

  2. Memories of a senior scientist: on passing the fiftieth anniversary of the beginning of deciphering the genetic code.

    PubMed

    Lengyel, Peter

    2012-01-01

    2011 marked the fiftieth anniversary of breaking the genetic code in 1961. Marshall Nirenberg, the National Institutes of Health (NIH) scientist who was awarded the Nobel Prize in Physiology or Medicine in 1968 for his role in deciphering the code, wrote in 2004 a personal account of his research. The race for the code was a competition between the NIH group and Severo Ochoa's laboratory at New York University (NYU) School of Medicine, where I was a graduate student and conducted many of the experiments. I am now 83 years old. These facts prompt me to recall how I, together with Joe Speyer, an instructor in the Department of Biochemistry at NYU, unexpectedly became involved in deciphering the code, which also became the basis of my PhD thesis. Ochoa won the Nobel Prize in Physiology or Medicine in 1959 for discovering polynucleotide phosphorylase (PNP), the first enzyme found to synthesize RNA in the test tube. The story of how PNP made the deciphering of the code feasible is recalled here. PMID:22994487

  3. Fluid/Gravity Correspondence, Second Order Transport and Gravitational Anomaly***

    NASA Astrophysics Data System (ADS)

    Megías, Eugenio; Pena-Benitez, Francisco

    2014-03-01

    We study the transport properties of a relativistic fluid affected by chiral and gauge-gravitational anomalies. The computation is performed in the framework of the fluid/gravity correspondence for a 5 dim holographic model with Chern-Simons terms in the action. We find new anomalous and non anomalous transport coefficients, as well as new contributions to the existing ones coming from the mixed gauge-gravitational anomaly. Consequences for the shear waves dispersion relation are analyzed. Talk given by E. Megías at the International Nuclear Physics Conference INPC 2013, 2-7 June 2013, Firenze, Italy.Supported by Plan Nacional de Altas Energías (FPA2009-07908, FPA2011-25948), Spanish MICINN Consolider-Ingenio 2010 Programme CPAN (CSD2007-00042), Comunidad de Madrid HEP-HACOS S2009/ESP-1473, Spanish MINECO's Centro de Excelencia Severo Ochoa Program (SEV-2012-0234, SEV-2012-0249), and the Juan de la Cierva Program.

  4. Strongly Coupled Models with a Higgs-like Boson

    NASA Astrophysics Data System (ADS)

    Pich, Antonio; Rosell, Ignasi; José Sanz-Cillero, Juan

    2013-11-01

    Considering the one-loop calculation of the oblique S and T parameters, we have presented a study of the viability of strongly-coupled scenarios of electroweak symmetry breaking with a light Higgs-like boson. The calculation has been done by using an effective Lagrangian, being short-distance constraints and dispersive relations the main ingredients of the estimation. Contrary to a widely spread believe, we have demonstrated that strongly coupled electroweak models with massive resonances are not in conflict with experimentalconstraints on these parameters and the recently observed Higgs-like resonance. So there is room for these models, but they are stringently constrained. The vector and axial-vector states should be heavy enough (with masses above the TeV scale), the mass splitting between them is highly preferred to be small and the Higgs-like scalar should have a WW coupling close to the Standard Model one. It is important to stress that these conclusions do not depend critically on the inclusion of the second Weinberg sum rule. We wish to thank the organizers of LHCP 2013 for the pleasant conference. This work has been supported in part by the Spanish Government and the European Commission [FPA2010-17747, FPA2011- 23778, AIC-D-2011-0818, SEV-2012-0249 (Severo Ochoa Program), CSD2007-00042 (Consolider Project CPAN)], the Generalitat Valenciana [PrometeoII/2013/007] and the Comunidad de Madrid [HEPHACOS S2009/ESP-1473].

  5. In Situ Decommissioning Sensor Network, Meso-Scale Test Bed - Phase 3 Fluid Injection Test Summary Report

    SciTech Connect

    Serrato, M. G.

    2013-09-27

    located at the Florida International University Applied Research Center, Miami, FL (FIU-ARC). A follow-on fluid injection test was developed to detect fluid and ion migration in a cementitious material/grouted test cube using a limited number of existing embedded sensor systems. This In Situ Decommissioning Sensor Network, Meso-Scale Test Bed (ISDSN-MSTB) - Phase 3 Fluid Injection Test Summary Report summarizes the test implementation, acquired and processed data, and results from the activated embedded sensor systems used during the fluid injection test. The ISDSN-MSTB Phase 3 Fluid Injection Test was conducted from August 27 through September 6, 2013 at the FIU-ARC ISDSN-MSTB test cube. The fluid injection test activated a portion of the existing embedded sensor systems in the ISDSN-MSTB test cube: Electrical Resistivity Tomography-Thermocouple Sensor Arrays, Advance Tensiometer Sensors, and Fiber Loop Ringdown Optical Sensors. These embedded sensor systems were activated 15 months after initial placement. All sensor systems were remotely operated and data acquisition was completed through the established Sensor Remote Access System (SRAS) hosted on the DOE D&D Knowledge Management Information Tool (D&D DKM-IT) server. The ISDN Phase 3 Fluid Injection Test successfully demonstrated the feasibility of embedding sensor systems to assess moisture-fluid flow and resulting transport potential for contaminate mobility through a cementitious material/grout monolith. The ISDSN embedded sensor systems activated for the fluid injection test highlighted the robustness of the sensor systems and the importance of configuring systems in-depth (i.e., complementary sensors and measurements) to alleviate data acquisition gaps.

  6. Quantifying moisture transport in cementitious materials using neutron radiography

    NASA Astrophysics Data System (ADS)

    Lucero, Catherine L.

    . It has been found through this study that small pores, namely voids created by chemical shrinkage, gel pores, and capillary pores, ranging from 0.5 nm to 50 microm, fill quickly through capillary action. However, large entrapped and entrained air voids ranging from 0.05 to 1.25 mm remain empty during the initial filling process. In mortar exposed to calcium chloride solution, a decrease in sorptivity was observed due to an increase in viscosity and surface tension of the solution as proposed by Spragg et al 2011. This work however also noted a decrease in the rate of absorption due to a reaction between the salt and matrix which results in the filling of the pores in the concrete. The results from neutron imaging can help in the interpretation of standard absorption tests. ASTM C1585 test results can be further analyzed in several ways that could give an accurate indication of the durability of the concrete. Results can be reported in depth of penetration versus the square root of time rather than mm3 of fluid per mm2 of exposed surface area. Since a known fraction of pores are initially filling before reaching the edge of the sample, the actual depth of penetration can be calculated. This work is compared with an 'intrinsic sorptivity' that can be used to interpret mass measurements. Furthermore, the influence of shrinkage reducing admixtures (SRAs) on drying was studied. Neutron radiographs showed that systems saturated in water remain "wetter" than systems saturated in 5% SRA solution. The SRA in the system reduces the moisture diffusion coefficient due an increase in viscosity and decrease in surface tension. Neutron radiography provided spatial information of the drying front that cannot be achieved using other methods.

  7. Population Pharmacokinetics of Gentamicin and Dosing Optimization for Infants

    PubMed Central

    Rueda-Naharro, Aída; Peña-Cabia, Silvia; García, Benito; Romano-Moreno, Silvia; Barcia, Emilia

    2014-01-01

    The aim of this study was to characterize and validate the population pharmacokinetics of gentamicin in infants and to determine the influences of clinically relevant covariates to explain the inter- and intraindividual variabilities associated with this drug. Infants receiving intravenous gentamicin and with routine therapeutic drug monitoring were consecutively enrolled in the study. Plasma concentration and time data were retrospectively collected from 208 infants (1 to 24 months old) of the Hospital Universitario Severo Ochoa (Spain), of whom 44% were males (mean age [± standard deviation], 5.8 ± 4.8 months; mean body weight, 6.4 ± 2.2 kg). Data analysis was performed with NONMEM 7.2. One- and two-compartment open models were analyzed to estimate the gentamicin population parameters and the influences of several covariates. External validation was carried out in another population of 55 infants. The behavior of gentamicin in infants exhibits two-compartment pharmacokinetics, with total body weight being the covariate that mainly influences central volume (Vc) and clearance (CL); this parameter was also related to creatinine clearance. Both parameters are age related and different from those reported for neonatal populations. On the basis of clinical presentation and diagnosis, a once-daily dosage regimen of 7 mg/kg of body weight every 24 h is proposed for intravenous gentamicin, followed by therapeutic drug monitoring in order to avoid toxicity and ensure efficacy with minimal blood sampling. Gentamicin pharmacokinetics and disposition were accurately characterized in this pediatric population (infants), with the parameters obtained being different from those reported for neonates and children. These differences should be considered in the dosing and therapeutic monitoring of this antibiotic. PMID:25385111

  8. Respiratory Syncytial Virus Coinfections With Rhinovirus and Human Bocavirus in Hospitalized Children

    PubMed Central

    Calvo, Cristina; García-García, María Luz; Pozo, Francisco; Paula, Gallardo; Molinero, Mar; Calderón, Ana; González-Esguevillas, Mónica; Casas, Inmaculada

    2015-01-01

    Abstract It is not clearly established if coinfections are more severe than single viral respiratory infections. The aim of the study was to study and to compare simple infections and viral coinfections of respiratory syncytial virus (RSV) in hospitalized children. From September 2005 to August 2013, a prospective study was conducted on children younger than 14 years of age, admitted with respiratory infection to the Pediatric Department of the Severo Ochoa Hospital, in Spain. Specimens of nasopharyngeal aspirate were taken for virological study by using polymerase chain reaction, and clinical data were recorded. Simple RSV infections were selected and compared with double infections of RSV with rhinovirus (RV) or with human bocavirus (HBoV). In this study, 2993 episodes corresponding to 2525 children were analyzed. At least 1 virus was detected in 77% (2312) of the episodes. Single infections (599 RSV, 513 RV, and 81 HBoV) were compared with 120 RSV-RV and 60 RSV-HBoV double infections. The RSV-RV coinfections had fever (63% vs 43%; P < 0.001) and hypoxia (70% vs 43%; P < 0.001) more often than RV infections. Hypoxia was similar between single or dual infections (71%). Bronchiolitis was more frequent in the RSV simple group (P < 0.001). Pediatric intensive care unit admission was more common in RSV simple or RSV-RV groups than in the RV monoinfection (P = 0.042). Hospitalization was longer for both RSV simple group and RSV-HBoV coinfection, lasting about 1 day (4.7 vs 3.8 days; P < 0.001) longer than in simple HBoV infections. There were no differences in PICU admission. RSV single group was of a younger age than the other groups. Coinfections between RSV-RV and RSV-HBoV are frequent. Overall viral coinfections do not present greater severity, but have mixed clinical features. PMID:26496310

  9. My life with bacteriophage phi29.

    PubMed

    Salas, Margarita

    2012-12-28

    This article is a survey of my scientific work over 52 years. During my postdoctoral stay in Severo Ochoa's laboratory, I determined the direction of reading of the genetic message, and I discovered two proteins that I showed to be involved in the initiation of protein synthesis. The work I have done in Spain with bacteriophage ϕ29 for 45 years has been very rewarding. I can say that I was lucky because I did not expect that ϕ29 would give so many interesting results, but I worked hard, with a lot of dedication and enthusiasm, and I was there when the luck arrived. I would like to emphasize our work on the control of ϕ29 DNA transcription and, in particular, the finding for the first time of a protein covalently linked to the 5'-ends of ϕ29 DNA that we later showed to be the primer for the initiation of phage DNA replication. Very relevant was the discovery of the ϕ29 DNA polymerase, with its properties of extremely high processivity and strand displacement capacity, together with its high fidelity. The ϕ29 DNA polymerase has become an ideal enzyme for DNA amplification, both rolling-circle and whole-genome linear amplification. I am also very proud of the many brilliant students and collaborators with whom I have worked over the years and who have become excellent scientists. This Reflections article is not intended to be the end of my scientific career. I expect to work for many years to come. PMID:23124207

  10. On the Fate of Debris Associated with the Disappearance of Flight MH370: a Dynamical System Perspective

    NASA Astrophysics Data System (ADS)

    Mancho, A. M.; Garcia-Garrido, V. J.; Wiggins, S.; Mendoza, C.

    2015-12-01

    The disappearance of Malaysia Airlines flight MH370 on the morning of the 8th of March 2014 is one of the great mysteries of our time. One relevant aspect of this mystery is that not a single piece of debris from the aircraft was found during the intensive surface search carried out in the months following the crash. Difficulties in the search efforts were due to the uncertainty in the plane's final impact point and the time passed since the accident and rise the question on how the debris was scattered in an always moving ocean, for which there exist multiple datasets that do not uniquely determine its state. Our approach to this problem is based on dynamical systems tools that identify dynamic barriers and coherent structures governing transport. By combining publicly available information supplied by different ocean data sources with these mathematical techniques, we are able to assess the spatio-temporal state of the ocean in the priority search area at the time of impact and the following weeks. Using this information we propose a revised search strategy by showing why one might not have expected to find debris in some large search areas targeted by the search services and determining regions where one might have expected impact debris to be located and that were not subjected to any exploration. This research has been supported by MINECO under grants MTM2014-56392-R and ICMAT Severo Ochoa project SEV-2011-0087 and ONR grant No. N00014- 01-1-0769. Computational support from CESGA is acknowledged. References [1] V. J. García-Garrido, A. M. Mancho, S. Wiggins, and C. Mendoza. A dynamical systems perspective on the absence of debris associated with the disappearance of flight MH370. Nonlin. Processes Geophys. Discuss., 2,1197-1225, doi:10.5194/npgd-2-1197-2015, 2015

  11. My Life with Bacteriophage φ29

    PubMed Central

    Salas, Margarita

    2012-01-01

    This article is a survey of my scientific work over 52 years. During my postdoctoral stay in Severo Ochoa's laboratory, I determined the direction of reading of the genetic message, and I discovered two proteins that I showed to be involved in the initiation of protein synthesis. The work I have done in Spain with bacteriophage φ29 for 45 years has been very rewarding. I can say that I was lucky because I did not expect that φ29 would give so many interesting results, but I worked hard, with a lot of dedication and enthusiasm, and I was there when the luck arrived. I would like to emphasize our work on the control of φ29 DNA transcription and, in particular, the finding for the first time of a protein covalently linked to the 5′-ends of φ29 DNA that we later showed to be the primer for the initiation of phage DNA replication. Very relevant was the discovery of the φ29 DNA polymerase, with its properties of extremely high processivity and strand displacement capacity, together with its high fidelity. The φ29 DNA polymerase has become an ideal enzyme for DNA amplification, both rolling-circle and whole-genome linear amplification. I am also very proud of the many brilliant students and collaborators with whom I have worked over the years and who have become excellent scientists. This Reflections article is not intended to be the end of my scientific career. I expect to work for many years to come. PMID:23124207

  12. The explosive activity of the Colima volcano in 2005

    NASA Astrophysics Data System (ADS)

    Suarez-Plascencia, C.; Nuñez-Cornu, F.; Diaz-Torres, J.

    2005-12-01

    The Colima volcano, Mexico, showed a new cycle of explosive activity beginning in March and April the 2005. This increased gradually and in May it appeared an explosive event which generated piroclastic flows on all flanks of the volcano. On May 23 a new dome was created, and it was observed from the Volcanological Observatory of the Nevado de Colima. Hours later its dome was destroyed by a strong explosion, which formed a column 3 km hight and piroclastic flows that reached a distance of 5 km on the ravines of the South sector. On May 30 the most intense explosion from 1999 occurred when the plume reached heights over 3.500 m above the crater, and piroclastic flows. In the month of June it generated four explosive events of characteristics similar to those of May. These constant explosions caused constant morphological changes on the top, being the most significant the collapse of the North and South walls of the crater in the first week of June, and the creation of a new crater in July. This activity was similar to the one shown in 1902-1903 and reported by Severo Diaz (1906), but without reaching the maximum levels of activity reported for 1903, where it had levels of three to five maximum explosive events per day. The explosions deposited great amount of nonconsolidated materials, like ash, lithics and rocks on the flanks of the volcano, which with the present rainy season have generated lahares, two in the month of June, ten in July and eight in August (RESCO reports). These have flowed in small flows on the ravines of La Lumbre, Montegrande, San Antonio and La Arena. None of them have caused damages until August, 2005.

  13. [Prevalence and seasonal variation of Pediculosis capitis in children and the young population of the health region, Buenos Aires, Argentina].

    PubMed

    Castro, D del C; Abrahamovich, A H; Cicchino, A C; Rigoni, A M; Raffaeli, C; de Barrio, A

    1994-08-01

    The prevalence of the parasitic disease Pediculosis capitis was studied over a period of one year from 1-8-1992 to 31-7-1993, in Sanitary Region XI of the Buenos Aires province, Argentina which is composed of 15 districts located on the ENE, and in other areas under the influence of the Hospital Interzonal de Agudos, Especialidad Pediatría "Sup. Sor María Ludovica" de Plata, center of this Sanitary Region. A total number of 552 individuals of from medium to medium low social level of the child population of from 0 to 16 years of age were sampled at random over 52 consecutive weeks. All individuals who actually had the parasite at the time of examination were considered as positive for this disease. The results are expressed in terms of prevalence and its monthly and seasonal variations analyzed. Prevalence showed high values during all months, the lowest being in February (12%) and the highest in August (56.8%), the annual mean being of 38.04% (+/- 4.05%). Seasonally, its lowest value occurred in the summer (16.8%), the values for the remaining seasons being very similar to one another, but always higher than 38%. PMID:7660026

  14. Astronomía para ciegos y amblíopes. Proyecto de construcción de un planetario especial en la ciudad de Mar del Plata

    NASA Astrophysics Data System (ADS)

    Musso, S.

    ?`Qué es la Astronomía para Ciegos?. El trabajo es una adaptación en base a la escala de magnitudes de Hipparco que cambia el concepto de luz por una adaptación sonora, donde las estrellas de magnitud 6 se escuchan en 10 dB, más o menos lo que consideramos el umbral de la audición humana. Quienes no escuchan muy bien no pueden escuchar las magnitudes 6, de la misma manera que muchos de nosotros, que no poseemos una visión perfecta, no podemos observar esas mismas estrellas en el cielo (más allá de la polución). A los astros de magnitud 5 vamos a relacionarlos a un sonido en 20 dB. Y así sucesivamente. También los colores estarán representados en una convención de graves a agudos y lo mismo algunas características del cielo. Por ejemplo, la Vía Láctea se mostrará como un ``ruido", como bien nos lo hicieron ver nuestros futuros destinatarios. En Mar del Plata nos encontramos ya trabajando en un proyecto que tiene como objetivo final la construcción del Primer Planetario Acústico del Mundo, una herramienta para la enseñanza de la astronomía, un espacio para la lucha contra la discriminación del discapacitado y una posibilidad de ``ver el cielo de un modo diferente".

  15. Impact of Frailty and Other Geriatric Syndromes on Clinical Management and Outcomes in Elderly Patients With Non-ST-Segment Elevation Acute Coronary Syndromes: Rationale and Design of the LONGEVO-SCA Registry.

    PubMed

    Alegre, Oriol; Ariza-Solé, Albert; Vidán, María T; Formiga, Francesc; Martínez-Sellés, Manuel; Bueno, Héctor; Sanchís, Juan; López-Palop, Ramón; Abu-Assi, Emad; Cequier, Àngel

    2016-07-01

    The incidence of acute coronary syndromes (ACS) is high in the elderly. Despite a high prevalence of frailty and other aging-related variables, little information exists about the optimal clinical management in patients with coexisting geriatric syndromes. The aim of the LONGEVO-SCA registry (Impacto de la Fragilidad y Otros Síndromes Geriátricos en el Manejo y Pronóstico Vital del Anciano con Síndrome Coronario Agudo sin Elevación de Segmento ST) is to assess the impact of aging-related variables on clinical management, prognosis, and functional status in elderly patients with ACS. A series of 500 consecutive octogenarian patients with non-ST-segment elevation ACS from 57 centers in Spain will be included. A comprehensive geriatric assessment will be performed during the admission, assessing functional status (Barthel Index, Lawton-Brody Index), frailty (FRAIL scale, Short Physical Performance Battery), comorbidity (Charlson Index), nutritional status (Mini Nutritional Assessment-Short Form), and quality of life (Seattle Angina Questionnaire). Patients will be managed according to current recommendations. The primary outcome will be the description of mortality and its causes at 6 months. Secondary outcomes will be changes in functional status and quality of life. Results from this study might significantly improve the knowledge about the impact of aging-related variables on management and outcomes of elderly patients with ACS. Clinical management of these patients has become a major health care problem due to the growing incidence of ACS in the elderly and its particularities. PMID:27362592

  16. Contamination in mafic mineral-rich calc-alkaline granites: a geochemical and Sr-Nd isotope study of the Neoproterozoic Piedade Granite, SE Brazil.

    PubMed

    Leite, Renato J; Janasi, Valdecir A; Martins, Lucelene

    2006-06-01

    The Piedade Granite (approximately 600 Ma) was emplaced shortly after the main phase of granite magmatism in the Agudos Grandes batholith, Apiaí-Guaxupé Terrane, SE Brazil. Its main units are: mafic mineral-rich porphyritic granites forming the border (peraluminous muscovite-biotite granodiorite-monzogranite MBmg unit) and core (metaluminous titanite-bearing biotite monzogranite BmgT unit) and felsic pink inequigranular granite (Bmg unit) between them. Bmg has high LaN/YbN (up to 100), Th/U (> 10) and low Rb, Nb and Ta, and can be a crustal melt derived from deep-seated sources with residual garnet and biotite. The core BmgT unit derived from oxidized magmas with high Mg# (approximately 45), Ba and Sr, fractionated REE patterns (LaN/YbN = 45), 87Sr/86Sr(t) approximately 0.710, epsilonNd(t) approximately -12 to -14, interpreted as being high-K calc-alkaline magmas contaminated with metasedimentary rocks that had upper-crust signature (high U, Cs, Ta). The mafic-rich peraluminous granites show a more evolved isotope signature (87Sr/86Sr(t) = 0.713-0.714; epsilonNd(t) = -14 to -16), similar to Bmg, and Mg# and incompatible trace-element concentrations intermediate between Bmg and BmgT. A model is presented in whichMBmgis envisaged as the product of contamination between a mafic mineral-rich magma consanguineous with BmgT and pure crustal melts akin to Bmg. PMID:16710571

  17. Adapting and improving resilience to climate change in communities (moravian community as a pilot), by creating new capabilities based on the implementation of a new water culture; protection and management of natural resources

    NASA Astrophysics Data System (ADS)

    Campos Gallo, A.

    2015-04-01

    Water, in all its dimensions and scope, concerns humans as civilization, individuals and communities immersed in an environment that faces serious environmental threats and changes. The efficient way to deal with this crisis is education of present and future generations, breaking paradigms, creating awareness and new development models, seeking community groups and forces to empower their water resource and care, manage and renew it in an efficient and sustainable manner. The multiple uses of water in personal uses, irrigation, agro-industry and clean energy production, transforms this resource in a strategic element to any nation. With support from the Centro Nacional de Alta Tecnologia (CeNAT), it was possible to formulate the "Agenda Ambiental de Moravia", agreeing to be the "Consejo Tecnico de Fuerzas Vivas" (CTFV) from Moravia - articulated network of stakeholders - the one that coordinate all actions refered to water Resources, pollution and cleaner technologies and protected Areas. CeNAT and CTFV have developed distinguished efforts to improve the Moravians quality of life, and this has led the initiative of constitution of a whole education and training project in rescuing the Upper Basin of the Rio Tarcoles, through the implementation of an ecological - recreative garden ("Parque Comunitario Pulmon Verde de Moravia"), fostersing good use of natural resources, and also works as a platform for training and awareness program in Sustainable Development, based on "Hacia una Nueva Cultura del Agua" (powered through the United Nations by Dr. Pedro Arrojo Agudo and his " Feria de Aguas, Rios y Pueblos", presented in many countries). This initiative is projected to the national and international communities, through the "Water International Conference", which propel initiatives, laws and decisions which enable the development of Costa Rica and other countries under a sustainable model, focused on this essential component for life on the planet.

  18. February 27, 2010 Chilean Tsunami in Pacific and its Arrival to North East Asia

    NASA Astrophysics Data System (ADS)

    Zaytsev, Andrey; Pelinovsky, EfiM.; Yalciner, Ahmet C.; Ozer, Ceren; Chernov, Anton; Kostenko, Irina; Shevchenko, Georgy

    2010-05-01

    Petropavlosk (Kamchatka), Severo-Kurilsk (Paramushir), Kurilsk (Iturup, coast of the Okhotsk sea), Malokurilskoe (Shikotan), Korsakov, Kholmsk and Aniva Bay (Sakhalin). These records and also other offshore DART records are analyzed and used for comparison of the modeling results with offshore and nearshore records. The transmission of tsunami waves through Sakhalin and Kuril straits and their propagation to nearby coasts are investigated. The spectral analysis of records in settlements of Sakhalin and Kurile Islands are investigated. The performance and capabilities of NAMI DANCE is also presented together with comparisons between the model, observations and discussions.

  19. [In Process Citation].

    PubMed

    López-López, Laura; Torres-Sánchez, Irene; González-Jiménez, Emilio; Díaz-Pelegrina, Ana; Merlos-Navarro, Silvia; Valenza, Marie Carmen

    2016-01-01

    Introducción: las alteraciones en el estado nutricional en pacientes con enfermedad pulmonar obstructiva crónica (EPOC) son frecuentes. La sintomatología y la funcionalidad de estos enfermos pueden estar relacionadas con la nutrición, incrementando su gravedad en los sujetos con malnutrición. Objetivos: el objetivo de esta investigación fue profundizar sobre el perfil clínico del paciente con EPOC malnutrido y relacionar el estado nutricional con la funcionalidad y con los síntomas de estos pacientes. Métodos: se desarrolló un estudio observacional en pacientes con EPOC severo. Se valoró el estado de dependencia, la calidad de vida, las comorbilidades y la ansiedad y depresión. La función respiratoria se valoró con el volumen espiratorio forzado en el primer segundo y la escala de Borg modificada y el estado nutricional, con el Mini Nutritional Assessment. La sintomatología fue evaluada mediante el Leicester Cough Questionnaire y el London Chest Activity of Daily Living Scale. Resultados: 154 sujetos fueron incluidos en este estudio, 98 de ellos fueron varones. Un grupo de 71 sujetos mostraron malnutrición y un grupo de 83 sujetos un estado nutricional normal. La comparación entre los grupos mostró características clínicas significativamente diferen- tes (p < 0,05). El análisis mostró diferencias significativas en la disnea (p = 0,043), así como en las subescalas de funcionalidad relacionadas con sintomatología respiratoria autocuidado (p = 0,040), actividades de ocio (p = 0,019) y la puntuación total (p = 0,031), siendo peores en los sujetos malnutridos. Conclusión: los pacientes con EPOC malnutridos presentan más síntomas y peores niveles de funcionalidad que los pacientes con EPOC con estado nutricional normal. PMID:27238793

  20. [In Process Citation].

    PubMed

    Chacón-Cuberos, Ramón; Castro-Sánchez, Manuel; Muros-Molina, José Joaquín; Espejo-Garcés, Tamara; Zurita-Ortega, Félix; Linares-Manrique, Marta

    2016-01-01

    Introducción: la dieta mediterránea (DM) representa uno de los modelos dietéticos más completos y sanos según expresan numerosos estudios. En este sentido, la etapa universitaria supone un cambio sustancial en los hábitos alimentarios de los adultos jóvenes, alejándose de los estándares asociados a la DM. Objetivo: determinar el nivel de adherencia a la DM de un sector de población universitaria, estableciendo patrones de relación con el tipo de población en el que reside y hábitos de ocio digital asociados a videojuegos. Material y métodos: en esta investigación de diseño descriptivo y corte transversal participaron 490 estudiantes universitarios (M = 22,8 años; DT = 3,639), realizándose la recogida de datos mediante los cuestionarios KIDMED, Cuestionario de Experiencias Relacionadas con los Videojuegos (CERV) y Cuestionario sobre los Hábitos de Consumo de Videojuegos (CHCV). Resultados: más del 70% de la muestra necesitaba mejorar su alimentación y solo un 26,1% se alimentaba adecuadamente. Asimismo, los niveles de adicción a los videojuegos mostraron que un 17,8% de los participantes manifestaba problemas potenciales y un 2,7% severos. Se encontraron diferencias estadísticas en las relaciones dadas para la adhesión a la DM, la frecuencia de uso de videojuegos y el número de videojuegos jugados, concretando que los hábitos de consumo de videojuegos influyen en la adhesión a la DM en la etapa universitaria. Conclusión: ante el bajo porcentaje de universitarios que siguen una dieta de calidad óptima y su relación con el uso de videojuegos, resulta de vital importancia la creación de programas de intervención que mejoren la alimentación de este sector y disminuyan el tiempo de ocio sedentario. PMID:27238805

  1. Modeling of a 1960'th Chilean tsunami in Pacific Ocean within nonlinear-dispersive theory of long waves

    NASA Astrophysics Data System (ADS)

    Chernov, A.; Korytko, A.; Kostenko, I.; Pelinovsky, E.; Yalciner, A.; Zaytsev, A.

    2009-04-01

    1960 Chilean centered Pacific Ocean tsunami and 2004 North West Sumatra centered Indian Ocean Tsunami are two important tsunamis of long distance propagation and impacts of tsunamis. Recent international studies on the propagation and dispersion effects of Indian Ocean tsunami showed that dispersion is one of the important parameters of numerical solutions of tsunami propagation. May 23, 1960 earthquake with the approximate magnitude 9.0 caused approximately 750km rupture and generated tsunami at offshore Chilean Coast. Tsunami has reached 15-20m height at Chilean coast. The effects of this tsunami were observed not only near Chilean Coast but also in Japan after 22 hours propagation. Chilean tsunami was also felt in Kuril Islands and tsunami height reached to 4.7m near Severo-Kurilsk (Paramushir Island). Houses near the coast, warehouses and mooring facilities have been flooded. In Malokurilsk (Shikotan Island), the height of tsunami reached 4m, flooded the moorings facilities and some buildings, and damaged the bridge on a land. Many vessels became stranded because of broken anchors. Tsunami was also observed on all islands of the Kuril Ridge. The maximal height of rising of water was 4m at Shikotan Islands and 2.2m at on Kunashir Island, 2.5m at Iturup Island, and 1.3-1.5m at Matua Island. Tsunami entered the Sea of Okhotsk. In Magadan the height of rising of water was 2.2 m. the weak tsunami also was observed near Sakhalin Island. The dispersion effect of 1960 Chilean tsunami and its long distance effects on Kuril Ridge have not been studied yet. In this study we developed the numerical model solving the long distance propagation of 1960 Chilean tsunami in Pacific Ocean and the assessment of its far field effects at Kuril Ridge. According to the modeling efforts, we made comparisons between the results of the numerical solutions using dispersive and non-dispersive long wave equations. The dispersion effects of long distance propagation of 1960 Chilean tsunami

  2. A Real-Time Response to a Marine Oil Spill: an Intedisciplinary Approach.

    NASA Astrophysics Data System (ADS)

    Garcia-Garrido, Victor J.; Ramos, Antonio; Mancho, Ana M.; Coca, Josep; Wiggins, Stephen

    2016-04-01

    By combining tools from dynamical systems theory and remote sensing techniques, we achieve a remarkable representation of the events following the sinking of the Oleg Naydenov fishing ship, that took place close to the Canary Islands in April 2015 [1]. The emergency services acquired a precise knowledge of the evolution of the spill, occurred after the sinking, by means of a formidable, extremely time-consuming and expensive effort. In this presentation we show that remote sensing techniques [2] allowed a direct observation of the spill in extensive areas. The time evolution of the observed spills was pursued by dynamical systems tools that, based on COPERNICUS IBI velocity fields data, were able to predict the impact of the spill in the coast of Gran Canaria. A deep description of the dispersion processes produced by ocean currents is achieved by means of Lagrangian Descriptors [3,4,5] that highlight an invisible but real dynamical skeleton, governing the transport processes in the area. This research is supported by MINECO ICMAT Severo Ochoa project SEV-2011-0087 and SEV-2015-0554 and grants MTM2014-56392-R, UNLP-13-3E-2664 (2013-2015) and ONR grant No. N00014- 01-1-0769. [1] V. J. García-Garrido, A. Ramos, A. M. Mancho, J. Coca, S. Wiggins. Assemblage of Tools for a Real-Time Response to a Marine Oil Spill. Preprint (2015). [2] A. Pisano, F. Bignami, R. Santoleri, Oil spill detection in glint-contaminated near-infrared MODIS imagery, Remote Sens. 7 (1) (2015) 1112-1134. [3] C. Mendoza, A. M. Mancho. The hidden geometry of ocean flows. Physical Review Letters 105 (2010), 3, 038501-1-038501-4. [4] A. M. Mancho, S. Wiggins, J. Curbelo, C. Mendoza. Lagrangian Descriptors: A Method for Revealing Phase Space Structures of General Time Dependent Dynamical Systems. Communications in Nonlinear Science and Numerical Simulation. 18 (2013) 3530-3557. [5] C. Lopesino, F. Balibrea, S. Wiggins, A.M. Mancho. Lagrangian Descriptors for Two Dimensional, Area Preserving

  3. Comparison of Eruptive Processes of the years 1903 and 2015 of the Colima Volcano, Mexico.

    NASA Astrophysics Data System (ADS)

    Suarez-Plascencia, C.; Nuñez-Cornu, F. J.; Hernandez-Rodriguez, A.; Suarez, G. B. V.; Arreola-Ochoa, L. C.

    2015-12-01

    The Colima volcano eruption processes during the months of January - July 2015, was characterized by two types of activity: From January to May we registered 923 exhalations and smaller explosions. Having up to 31 events per day, the columns of ash reached an altitude between 4500 and 7000 masl. Each event frequently averaging between 50 and 500 meters from about 442 or 48% of the total events this period. The reports of falling ash came from as far as the city of Salamanca at 278 km to the NE. The intense activity destroyed the original dome forming a new one with an elliptical crater 224 m by 166 m and 35 m deep. On May 15 we observed the growth of a new dome. On July 4, this created the falling of rocks along the slopes and the formation of three Andesitic lava flows at the N, SW and S flanks. By July 11 the volume of lava extruded was about 6 x106 m3, with a rate extrusion of 1.21 m3per sec. 2. Based on three flyby observations, it was noted that the lava flows on the S and SW sectors had a higher extrusion rate in the N sector. The first two were placed on a slope with an average gradient of 36º, while on the northern slope gradient is 23º, as a result of the interaction of extrusion speed, slope and height of the lava front, there were constant landslides, causing at least 4 Merapi type pyroclastic flows, that flowed by the gullies of Montegrande and San Antonio. The first flow reached distances of 7 km and 10.4 km. It is the largest lava flow recorded since January 20, 1913. The devastating results were the burning of 500 meters of the Templado Forest, burning along the Montegrande Creek and finally affecting many crops and livestock. This type of activity already had shown in 1975 and 1991 by the lava flow and S NE flank where the pyroclastic flows had no destructive effects, except for some small fires in forested areas at the base of the volcano (Thorpe, et al, 1977). In March 1903 Colima volcano showed similar activity per Arreola J. and Diaz Severo

  4. Dust Model Intercomparison and Extensive Comparison to Observations in the Western Mediterranean for the Summer 2012 Pre-ChArMEx/TRAQA Campaign

    NASA Astrophysics Data System (ADS)

    Basart, S.; Dulac, F.; Baldasano, J. M.

    2014-12-01

    campaign were ADEME and INSU under the umbrella of the programmes PRIMEQUAL and MISTRALS. LOAC was developed with funding from ANR. BSC acknowledges the support from the grant SEV-2011-00067 of Severo Ochoa Program, awarded by the Spanish Government.

  5. Lagrangian descriptors and their applications to oceanic and atmospheric flows

    NASA Astrophysics Data System (ADS)

    Mancho, A. M.

    2012-12-01

    Geometry has been a very useful approach for studying dynamical systems. At the basis are Poincare ideas of seeking structures on the phase space that divide it into regions corresponding to trajectories with different dynamical fates. These ideas have demonstrated to be very powerful for the description of transport in purely advective flows and important applications have been found in geophysics. This presentation explores the performance of new Lagrangian tools, so called, Lagrangian descriptors [1,2,3], which are based on the integration along trajectories of bounded positive scalars which express an intrinsic geometrical or physical property of the trajectory. We analyze the convenience of different descriptors from several points of view and compare outputs with other methods proposed in the literature. We discuss applications of these new tools on oceanic datasets taken from altimeter satellites on the Kuroshio region, and on reanalysis data on the Antarctic polar vortex [4,5,6]. This research has been supported by MINECO under grants MTM2011-26696 and ICMAT Severo Ochoa project SEV-2011-0087 and CSIC under grant ILINK-0145. Computational support from CESGA and CCC-UAM is acknowledged. [1] J. A. J. Madrid, A. M. Mancho. Distinguished trajectories in time dependent vector fields. Chaos 19 (2009), 013111-1-013111-18. [2] C. Mendoza, A. M. Mancho. The hidden geometry of ocean flows. Physical Review Letters 105 (2010), 3, 038501-1-038501-4. [3], A. M. Mancho, S. Wiggins, J. Curbelo, C. Mendoza. In preparation. [4] A. de la Cámara, A. M. Mancho, K. Ide, E. Serrano, C.R. Mechoso. Routes of transport across the Antarctic polar vortex in the southern spring. Journal of Atmospheric Sciences 69, 2 (2012). [5] C. Mendoza, A. M. Mancho, M. H. Rio. The turnstile mechanism across the Kuroshio current: analysis of dynamics in altimeter velocity fields. Nonlinear Proc. Geoph 17 (2010), 2, 103-111. [6] Carolina Mendoza, Ana M. Mancho. The Lagrangian description of

  6. The effect of water structure and solute hydration on the kinetics of mineral growth and dissolution (Arne Richter Award for Outstanding Young Scientists)

    NASA Astrophysics Data System (ADS)

    Ruiz-Agudo, E.; Putnis, C. V.; Putnis, A.

    2012-04-01

    Classical crystal growth theory relates growth and dissolution rates to the degree of supersaturation. However, the solution composition may also affect the growth rate of carbonate minerals, via the Ca2+ to CO32- concentration ratio (e.g. Perdikouri et al., 2009; Stack and Grantham, 2010), ionic strength (e.g. Ruiz-Agudo et al. 2010) or the presence of organic matter (Hoch et al., 2000). For this reason, the influence of these parameters on the kinetics of mineral growth and dissolution has generated a considerable amount of research in the last decade. In particular, effects of both inorganic and organic impurities on mineral growth and dissolution have been frequently reported in the literature. Commonly, water in contact with rock forming minerals, contains significant and variable amounts of ions in solution. The effect of such ions on dissolution and growth rates has been traditionally ascribed to changes in solubility. However, experimental studies performed on different minerals have shown that the dependence of growth or dissolution rates on ionic strength is complex, and that the effect of ionic strength is not independent of the ionic species producing it. Here, we report investigations aimed at addressing the basic hypothesis that mineral growth and dissolution is governed by complex interactions between solvent structure, surface hydration and the ion solvation environment induced by the presence of electrolytes. It is proposed that any factor affecting ion solvation should alter growth and dissolution rates. These results have opened the possibility of a new understanding of very diverse phenomena in geochemistry and demonstrate the need for the inclusion of this "hydration effect" in the development of predictive models that describe crystal growth and dissolution in complex systems, such as those found in nature. Furthermore, we can hypothesise that ion-assisted dehydration of trace and minor element ions could occur in biological systems, thus

  7. USGS research on geohazards of the North Pacific: past, present, and future

    NASA Astrophysics Data System (ADS)

    McNutt, M. K.; Eichelberger, J. C.

    2012-12-01

    The disastrous earthquakes and tsunamis of Sumatra in 2004 and Tohoku in 2011 have driven re-examination of where and how such events occur. Particular focus is on the North Pacific. Of the top 30 earthquakes recorded instrumentally worldwide, 50% occurred along the line of subduction from the Kuril Islands to the southern Alaska mainland. This region has seen monstrous volcanic eruptions (Katmai-Novarupta, 1912), destructive tsunamis (Severo-Kurilsk, 1952), and one of Earth's largest instrumentally-recorded earthquakes (M9.2 Alaska, 1964). Only the modest populations in these frontier towns half a century ago kept losses to a minimum. Impact of any natural disaster to population, vital infrastructure, and sea and air transportation would be magnified today. While USGS had a presence in Alaska for more than a century, the great Alaska earthquake of 1964 ushered in the first understanding of the area's risks. This was the first mega-thrust earthquake properly interpreted as such, and led to re-examination of the 1960 Chilean event. All modern conceptions of mega-thrust earthquakes and tsunamis derive some heritage from USGS research following the 1964 event. The discovery of oil in the Alaska Arctic prompted building a pipeline from the north slope of Alaska to the ice-free port of Valdez. The USGS identified risks from crossing permafrost and active faults. Accurate characterization of these hazards informed innovative designs that kept the pipeline from rupturing due to ground instability or during the M7.9 Denali earthquake of 2002. As a large state with few roads, air travel is common in Alaska. The frequent ash eruptions of volcanoes in the populous Cook Inlet basin became a serious issue, highlighted by the near-crash of a large passenger jet in 1989. In response, the USGS and its partners developed and deployed efficient seismic networks on remote volcanoes and initiated regular satellite surveillance for early warning of ash eruptions. Close collaboration

  8. Geothermal resources and energy complex use in Russia

    NASA Astrophysics Data System (ADS)

    Svalova, V.

    2009-04-01

    Geothermal energy use is the perspective way to clean sustainable development of the world. Russia has rich high and low temperature geothermal resources and makes good steps in their use. In Russia the geothermal resources are used predominantly for heat supply both heating of several cities and settlements on Northern Caucasus and Kamchatka with a total number of the population 500000. Besides in some regions of country the deep heat is used for greenhouses of common area 465000 m2. Most active the hydrothermal resources are used in Krasnodar territory, Dagestan and on Kamchatka. The approximately half of extracted resources is applied for heat supply of habitation and industrial puttings, third - to a heating of greenhouses, and about 13 % - for industrial processes. Besides the thermal waters are used approximately on 150 health resorts and 40 factories on bottling mineral water. The most perspective direction of usage of low temperature geothermal resources is the use of heat pumps. This way is optimal for many regions of Russia - in its European part, on Ural and others. The electricity is generated by some geothermal power plants (GeoPP) only in the Kamchatka Peninsula and Kuril Islands. At present three stations work in Kamchatka: Pauzhetka GeoPP (11MW e installed capacity) and two Severo-Mutnovka GeoPP ( 12 and 50 MWe). Moreover, another GeoPP of 100 MVe is now under preparation in the same place. Two small GeoPP are in operation in Kuril's Kunashir Isl, and Iturup Isl, with installed capacity of 2,б MWe and 6 MWe respectively. There are two possible uses of geothermal resources depending on structure and properties of thermal waters: heat/power and mineral extraction. The heat/power direction is preferable for low mineralized waters when valuable components in industrial concentration are absent, and the general mineralization does not interfere with normal operation of system. When high potential geothermal waters are characterized by the high

  9. New exposure ages for the Last Glacial Cycle in the Sanabria Lake region (northwestern Spain)

    NASA Astrophysics Data System (ADS)

    Rodríguez-Rodríguez, Laura; Jiménez-Sánchez, Montserrat; Domínguez-Cuesta, María Jose; Rinterknecht, Vincent; Pallàs, Raimon; Braucher, Régis; Bourlès, Didier; Valero-Garcés, Blas

    2013-04-01

    ., 2011. Last deglaciation in northwestern Spain: New chronological and geomorphologic evidence from the Sanabria region. Geomorphology 135, 48-65. Palacios, D., Andrés, N., Úbeda, J., Alcalá, J., Marcos, J., Vázquez-Selem, L., 2012. The importance of poligenic moraines in the paleoclimatic interpretation from cosmogenic dating. Geophysical Research Abstracts 14, EGU2012-3759-1. Pérez-Alberti, A., Valcárcel-Díaz, M., Martini, I.P., Pascucci, V., Andrucci, S., 2011. Upper Pleistocene glacial valley-junction sediments at Pias, Trevinca Mountains, NW Spain. In: Martini, I.P., French, H.M., Pérez-Alberti, A. (Eds.), Ice-Marginal and Periglacial Processes and Sediments. Geological Society (London) Special Publication 354, pp. 93-110. Research funded by the projects LIMNOCLIBER (REN2003-09130-C02-02), IBERLIMNO (CGL2005-20236-E/CLI), LIMNOCAL (CGL2006-13327-C04-01) and GRACCIE (CSD2007-00067) of the Spanish Inter-Ministry Commission of Science and Technology (CICYT). Additional funding was provided by the Fundación Patrimonio Natural de Castilla y León through the project "La investigacion en el Lago de Sanabria dentro del proyecto CALIBRE: perspectivas y posibilidades", and by the projects Consolider Ingenio 2006 (CSD2006-0041, Topo-Iberia), 2003 PIRA 00256, HF02.4, and RISKNAT (2009SGR520). L. Rodríguez-Rodríguez has developed her research under a Severo Ochoa Programme fellowship (FICYT- Asturias).

  10. Como Lo Hago Yo: Mielomeningocele En Bolivia

    PubMed Central

    Dabdoub, Carlos F.; Dabdoub, Carlos B.; Villavicencio, Ramiro; Quevedo, Germán

    2014-01-01

    Introducción: Las malformaciones del tubo neural (MTN) representan la segunda causa más frecuente de anomalías congénitas, luego de las cardiopatías. En este grupo se destaca el mielomeningocele (MMC) por su mayor incidencia, y por ser la más incapacitante y la más compleja entre todas las demás malformaciones del sistema nervioso c`entral (SNC). En Bolivia, como en muchos países de Sudamérica, los bajos niveles socio-culturales y la debilidad en el sistema sanitario, hacen que su incidencia y su morbilidad, sean mayores que en las naciones más desarrolladas. Material y Métodos: Se realizó un estudio retrospectivo y descriptivo de 70 casos de MMC, atendidos por un equipo multidisciplinario en el Hospital Universitario Japonés (HUJ) de Santa Cruz de la Sierra, entre 2008-2011. De ellos, 60 fueron intervenidos quirúrgicamente. Resultados: Se realizaron controles prenatales sólo en 27 mujeres (38.6%), diagnosticándose una disrafia espinal en apenas dos casos (7.4%). La edad de ingreso del MMC en su mayoría fue después de las 24 horas (65.6%), predominando su localización en la región lumbosacra (64.3%). De ellos, 67.2% eran abiertos, presentando un 32.9% un daño neurológico motor parcial mientras que 47.1% tenían paraplejia por debajo de la lesión. De los 70 casos, tres (4.3%) no fueron intervenidos, por presentar defectos congénitos severos o estado general grave. Las principales complicaciones posoperatorias inmediatas fueron: dehiscencia de sutura y/o infección de la herida (16.6%), fístula de líquido cefalorraquídeo (LCR) (10%) e infección del SNC (11.7%). La mortalidad general y postoperatoria fue de 7.1% y 3.3%, respectivamente. Al mes de vida presentaban hidrocefalia un 80% de los pacientes operados, colocándose una derivación ventriculoperitoneal (DVP) de presión media. De 9 pacientes que tuvieron un acompanamiento de dos o más años, seis presentaron una médula anclada, que fueron intervenidas quirúrgicamente. Conclusi

  11. Quaternary glacial geomorphosites from the Cantabrian Mountains (northern Iberian Peninsula): the Redes Natural Reservation and Picos de Europa Regional Park

    NASA Astrophysics Data System (ADS)

    Rodríguez-Rodríguez, Laura; Jiménez-Sánchez, Montserrat; José Domínguez-Cuesta, María

    2013-04-01

    the Quaternary glaciations, especially after the last local glacial maximum. Jiménez-Sánchez, M., Rodríguez-Rodríguez, L., García-Ruiz, J.M., Domínguez-Cuesta, M.J., Farias, P., Valero-Garcés, B., Moreno, A., Rico, M., Valcárcel, M., in press. A review of glacial geomorphology and chronology in northern Spain: timing and regional variability during the last glacial cycle. Geomorphology, doi: 10.1016/j.geomorph.2012.06.009. Serrano, E., González-Trueba, J.J., Pellitero, R., González-García, M., Gómez-Lende, M., in press. Quaternary glacial evolution in the Central Cantabrian Mountains (Northern Spain). Geomorphology, doi:10.1016/j.geomorph.2012.05.001. Research funded by the project CANDELA (CGL2012-31938) of the Spanish national research program in Earth Sciences and Hydric Resources (MICINN) and the project FC-11-PC-10-14 (FICYT-Asturias). L. Rodríguez-Rodríguez has developed her research under a grant of the Severo Ochoa Program (FICYT- Asturias).

  12. Elastoplasticidad anisotropa de metales en grandes deformaciones

    NASA Astrophysics Data System (ADS)

    Caminero Torija, Miguel Angel

    Eterovic y Bathe para incluir la posibilidad de plasticidad anisotropa con endurecimiento mixto. Este primer algoritmo esta restringido a casos de isotropia elastica. La isotropia elastica es una hipotesis bastante habitual en plasticidad anisotropa y tiene la ventaja de que permite el uso de formulaciones mixtas u/p. El segundo algoritmo, mas complejo y general, incluye la posibilidad de elasticidad anisotropa, plasticidad anisotropa y endurecimiento mixto. Este algoritmo supone una contribucion importante ya que esta basado en hipotesis comunmente aceptadas y utilizadas en elastoplasticidad isotropa: descomposicion multiplicativa del gradiente de deformaciones en parte elastica y parte plastica, descripcion hiperelastica sencilla en funcion de deformaciones logaritmicas e integracion exponencial que conserva el volumen. Ademas, la estructura final del algoritmo es modular y relativamente sencilla, consistiendo en un pre- y un postprocesador geometrico y una correccion plastica realizada en pequenas deformaciones. El algoritmo esta consistentemente linealizado para conservar la convergencia cuadratica asintotica de los metodos de Newton y la forma final que toma dicha linealizacion es similar al caso de isotropia elastoplastica implementado; consiste en el modulo tangente algoritmico de pequenas deformaciones sobre el que se aplica una transformacion para convertirlo en el de grandes deformaciones. Todos estos modelos han sido implementados en un codigo propio de elementos finitos denominado DULCINEA, el cual tiene formulaciones lagrangianas totales y actualizadas para grandes deformaciones. Una de las tareas necesarias para poder realizar las simulaciones, ha sido el estudio e implementacion de diferentes elementos que no sufran el bloqueo volumetrico severo que se observa en formulaciones estandar basadas en desplazamientos. Este bloqueo se debe a la condicion de quasi-incompresibilidad que imponen los modelos de plasticidad desviadores y consiste en una respuesta

  13. [Not Available].

    PubMed

    De Abajo Larriba, Ana Beatriz; Díaz Rodríguez, Ángel; González-Gallego, Javier; Méndez Rodríguez, Enrique; Álvarez Álvarez, María Jesús; Capón Álvarez, Jessica; Peleteiro Cobo, Beatriz; Mahmoud Atoui, Omar; De Abajo Olea, Serafín; Martínez de Mandojana Hernández, Juan

    2016-01-01

    Introducción: estimar la prevalencia del tabaquismo y analizar cómo se diagnostican y se trata a los fumadores diagnosticados de EPOC.Métodos: estudio epidemiológico, transversal, multicéntrico (30 centros salud de la provincia de León). Incluyó pacientes mayores de 35 años diagnosticados y tratados de EPOC. Variables analizadas: edad, sexo, hábitat, datos antropométricos, tabaquismo, número de paquetes/año, cooximetría, dependencia (escala analógico-visual), motivación (test de Fagerström), autoeficacia, estado anímico, intentos previos, terapia cognitivo-conductual, tratamiento farmacológico (TSN, bupropión, vareniclina) y recaídas. Los resultados se expresan con sus IC al 95,5%.Resultados: se incluyó a 833 pacientes, el 85,8% varones, edad media: 64,69 (53,66-75,61) años y 20,65 (4,47-36,8) años de evolución de la EPOC. El 86,67% (80,30-93,30) tenían antecedentes de tabaquismo (n = 722), de 35,26 (17,87-52,64) años de evolución, con consumo medio 28,36 (9,60-46,86) paquetes año, p < 0,001, siendo el 58% fumadores severos. El 57,4% (53,90-60,60) son exfumadores. El 29,3% (26,40-32,70) fumadores activos declarados vs. 35,11% (33,90-37,12) fumadores diagnosticados por cooximetría p < 0,05. Los 288 fumadores activos, presentaban baja motivación (49,80%), alta dependencia (49,5%), actitud negativa (52,60%), bajo estado de ánimo (32,05%), con 2,72 (1,74-3,67) intentos para dejar de fumar, p < 0,0001. La terapia conductivo-conductual (TCC) combinado con tratamiento farmacológico se realizó en el 55,8% (52,2-54,9), p < 0,05; La intervención más efectiva fue TCC combinada con vareniclina logrando una abstinencia del 29,86%. En total dejaron de fumar un 51,05% (49,49-52,70) de los pacientes con EPOC, p < 0,001.Conclusiones: la prevalencia de tabaquismo en la EPOC en nuestro medio continúa siendo inadmisiblemente elevada. Es necesaria una mayor implicación para disminuir su impacto en la salud de estos pacientes. PMID:27571673

  14. Variabilidad de la Estación de Crecimiento en la Región Sur de Tamaulipas en condiciones climaticas actuales y futuras.

    NASA Astrophysics Data System (ADS)

    Medina-Barrios, M.; Conde-Alvarez, C.; Gay-Garcia, C.

    2007-05-01

    El impacto de la variabilidad y cambio climáticos, afectan el potencial agrícola de la Región Sur de Tamaulipas. Además de los cambios estacionales, bajos rendimientos agrícolas, el manejo de los cultivos y las políticas locales de producción, existe la incertidumbre del mercado regional para los pequeños y grandes productores. La diversificación agrícola ha sido una alternativa para enfrentar las condiciones imperantes en esta región. Pero ésta ha provocado la fragmentación territorial, por lo que sólo algunos productores logran competir en un mercado nacional. Existe una preocupación generalizada por buscar soluciones que permitan que la población que es afectada por la inseguridad de la producción agrícola y económica, pueda adaptarse a las variaciones climáticas que afectan el proceso productivo. La seguridad alimentaría queda sujeta a la fluctuación de las importaciones para los sectores básicos y a las estrategias mercantiles de empresas trasnacionales. La percepción local sugiere un número creciente de eventos climatológicos extremos, constantes y severos en los últimos 20 años, con el aumento creciente de pérdidas económicas. El análisis se centra en la disponibilidad de agua, agregándose un aspecto de capital importancia como es la variabilidad interanual de la lluvia, que condiciona muy fuertemente el riesgo agrícola en el trópico seco, siendo ésta la que determina el momento de inicio de la estación favorable para el crecimiento y su duración. En este trabajo se han obtenido modelos de la distribución espacial de la precipitación y temperaturas, para el escenario base 1961-1990, el escenario actual 1971-2000, para algunos años El Niño y La Niña, así como para los escenarios de Cambio Climático HADLEY, ECHAM y GFDL, con escenarios A2 y B2, para las décadas de los 20s y 50s, para establecer el inicio y duración de la Estación de Crecimiento, utilizando Sistemas de Información Geográfica (ArcView). Estos

  15. Physical Stress Echocardiography: Prediction of Mortality and Cardiac Events in Patients with Exercise Test showing Ischemia.

    PubMed

    Araujo, Ana Carla Pereira de; Santos, Bruno F de Oliveira; Calasans, Flavia Ricci; Pinto, Ibraim M Francisco; Oliveira, Daniel Pio de; Melo, Luiza Dantas; Andrade, Stephanie Macedo; Tavares, Irlaneide da Silva; Sousa, Antonio Carlos Sobral; Oliveira, Joselina Luzia Menezes

    2014-11-01

    ísico na doença arterial coronária, mas a predição de mortalidade e de eventos cardíacos maiores, em pacientes com teste ergométrico positivo para isquemia miocárdica, é limitada. Objetivo: Avaliar a predição de mortalidade e de eventos cardíacos maiores pela ecocardiografia com estresse físico em pacientes com teste ergométrico positivo para isquemia miocárdica. Métodos: Trata-se de uma coorte retrospectiva em que foram estudados 866 pacientes consecutivos, com teste ergométrico positivo para isquemia miocárdica, submetidos à ecocardiografia com estresse físico. Os pacientes foram divididos em dois grupos: ecocardiografia com estresse físico negativa (G1) ou positiva (G2) para isquemia miocárdica. Os desfechos avaliados foram mortalidade por qualquer causa e eventos cardíacos maiores, definidos como óbito cardíaco e infarto agudo do miocárdio não fatal. Resultados: O G2 constituiu-se de 205 (23,7%) pacientes. Durante o seguimento médio de 85,6 ± 15,0 meses, ocorreram 26 óbitos, sendo seis por causa cardíaca, e 25 casos de infarto agudo do miocárdio não fatais. Os preditores independentes de mortalidade foram idade, diabetes melito e a ecocardiografia com estresse físico + (hazard ratio: 2,69; intervalo de confiança de 95%: 1,20 - 6,01; p = 0,016), com os seguintes eventos cardíacos maiores: idade, doença arterial coronária prévia, ecocardiografia com estresse físico + (hazard ratio: 2,75; intervalo de confiança de 95%: 1,15 - 6,53; p = 0,022) e ausência do incremento de 10% na fração de ejeção. A mortalidade por qualquer causa e os eventos cardíacos maiores foram significativamente superiores no G2 (p < 0, 001 e p = 0,001, respectivamente). Conclusão: A ecocardiografia com estresse físico oferece informações prognósticas adicionais em pacientes com teste ergométrico positivo para isquemia miocárdica. PMID:25352460

  16. Relantionships between gold mineralization and granite - Discussion with the support of a pluridisciplinary study of the Passa Tres gold deposit (South Brazil)

    NASA Astrophysics Data System (ADS)

    Dressel, Bárbara; Chauvet, Alain; Trzaskos, Barbara; Biondi, Joao Carlos; Bruguier, Olivier; Monie, Patrick; Villanova, Sandro; Bazille, Jose

    2016-04-01

    The Passa Três Granite, located at East of the Paraná State is elongated following a NNE-SSW direction. This sienogranite is emplaced within metapelites of the meso to neoproterozoic Açungui Group, between the Morro Agudo and Lancinha transcurrent faults, comprising the N040°E trending Lancinha Transcurrent Fault System. Gold mineralization within the Passa Três Granite is constituted by huge quartz veins with sulfides, variable quantities of fluorite and carbonates, forming orebodies with different internal textures, including massive, banded, sheared and brecciated. Structural data indicate the existence of two major fault systems, one N-S and the other E-W, with dips of 15-45°W and 20-75°S, respectively. Both NS and EW systems are interpreted to be contemporaneous and conjugate. Normal motions are everywhere suspected and main mineralized veins are located at opening sites at these fault systems, such as pull-aparts. The structural model suggests that the normal motion can be initiated by shearing along a "guide" level, in which sulfides and clay minerals are concentrated. This configuration can be observed at several scales, such as field, hand samples and thin section. Mineralized veins mainly contain, in addition to the quartz of the gangue, sulphides (pyrite, chalcopyrite, galena, molybdenite), fluorite, chlorite, muscovite, sericite, and carbonate. The presence of sericite, kaolinite and chlorite indicate the occurrence of, at least, propylitic and phyllic-type alterations, both in core of the granite and best-expressed at the rim of quartz-rich orebodies. Gold occurs as native grains in core of the quartz veins, within fractures that affect pyrite and frequently exhibiting normal motions consistent with the one observed at larger scale and systematically associated with chalcopyrite and galena. Quartz veins are sometimes bordered by aplitic dike. Additionally, some of the veins can exhibit a very thin margin of adularia minerals that seems to

  17. Elastoplasticidad anisotropa de metales en grandes deformaciones

    NASA Astrophysics Data System (ADS)

    Caminero Torija, Miguel Angel

    Eterovic y Bathe para incluir la posibilidad de plasticidad anisotropa con endurecimiento mixto. Este primer algoritmo esta restringido a casos de isotropia elastica. La isotropia elastica es una hipotesis bastante habitual en plasticidad anisotropa y tiene la ventaja de que permite el uso de formulaciones mixtas u/p. El segundo algoritmo, mas complejo y general, incluye la posibilidad de elasticidad anisotropa, plasticidad anisotropa y endurecimiento mixto. Este algoritmo supone una contribucion importante ya que esta basado en hipotesis comunmente aceptadas y utilizadas en elastoplasticidad isotropa: descomposicion multiplicativa del gradiente de deformaciones en parte elastica y parte plastica, descripcion hiperelastica sencilla en funcion de deformaciones logaritmicas e integracion exponencial que conserva el volumen. Ademas, la estructura final del algoritmo es modular y relativamente sencilla, consistiendo en un pre- y un postprocesador geometrico y una correccion plastica realizada en pequenas deformaciones. El algoritmo esta consistentemente linealizado para conservar la convergencia cuadratica asintotica de los metodos de Newton y la forma final que toma dicha linealizacion es similar al caso de isotropia elastoplastica implementado; consiste en el modulo tangente algoritmico de pequenas deformaciones sobre el que se aplica una transformacion para convertirlo en el de grandes deformaciones. Todos estos modelos han sido implementados en un codigo propio de elementos finitos denominado DULCINEA, el cual tiene formulaciones lagrangianas totales y actualizadas para grandes deformaciones. Una de las tareas necesarias para poder realizar las simulaciones, ha sido el estudio e implementacion de diferentes elementos que no sufran el bloqueo volumetrico severo que se observa en formulaciones estandar basadas en desplazamientos. Este bloqueo se debe a la condicion de quasi-incompresibilidad que imponen los modelos de plasticidad desviadores y consiste en una respuesta

  18. Quality of surgical care in hospitals providing internship training in Kenya: a cross sectional survey.

    PubMed Central

    Mwinga, Stephen; Kulohoma, Colette; Mwaniki, Paul; Idowu, Rachel; Masasabi, John; English, Mike

    2015-01-01

    los resultados y procesos de cuidados para condiciones prioritarias especificadas previamente (traumatismo craneoencefálico, lesión torácica, fracturas, quemaduras y abdomen agudo) mediante la auditoría de historias clínicas. Resultados Cada hospital tenía al menos un cirujano consultor. Se entregaban una vez por semana las listas de intervenciones quirúrgicas programadas en clínicas ambulatorias, en las rondas de visitas a las principales salas y las cirugías electivas (medio día) en 91%, 55% y 9% de los hospitales, respectivamente. En los demás hospitales se llevaban a cabo dos veces por semana. Los medicamentos básicos no estaban siempre disponibles (ej. gentamicina, morfina y meperidina en 50%, penicilina anti-estafilocócica inyectable 5% de los hospitales). Menos de la mitad de los hospitales tenían todos los recursos necesarios para proveer oxígeno. En 145 de 956 casos evaluados se llevó a cabo la cirugía con anestesia general o intradural. Encontramos apuntes quirúrgicos para un 99% y registros de la anestesia para el 72%. Se tenían registros de los signos vitales pre-quirúrgicos en un 80% de los casos y evidencia del consentimiento del paciente a ser intervenido en un 78%. Se documentaba pérdida de sangre solo en un caso y conteo de esponjas e instrumental en un 7%. Conclusiones La evaluación de los servicios quirúrgicos podría mejorarse mediante el desarrollo y la diseminación de estándares de cuidados precisos. Este estudio sugiere que los hospitales universitarios podrían estar mal equipados y los cuidados documentados sugieren que existen deficiencias tanto a nivel calidad como en el entrenamiento. PMID:25348925