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Sample records for air pollution epidemiological

  1. Exposure measurement for air-pollution epidemiology

    SciTech Connect

    Ferris, B.G.; Ware, J.H.; Spengler, J.D.

    1988-08-01

    The chapter describes the evolution of air-pollution epidemiology over a period when changes in pollution technologies have both lowered total exposures and dispersed them over vastly greater areas. Since personal exposure and microenvironmental measurements are expensive, studies oriented toward measurements of total exposure will be smaller and more intensive. The shift in emphasis to total human exposure also will affect health risk assessment and raise difficult issues in the regulatory domain. Considering that outdoor exposures (for which EPA has a regulatory mandate) occur in the context of exposures from other sources, the potential effect of regulatory action would probably be small. The regulatory issues are even more difficult for particulate air pollution since cigarette smoking is the strongest determinant of indoor levels but the EPA lacks regulatory responsibility for cigarette smoke.

  2. Critical issues in air pollution epidemiology.

    PubMed Central

    Lippmann, M; Lioy, P J

    1985-01-01

    The epidemiological studies which have had significant impact on the setting of National Ambient Air Quality Standards (NAAQSs) were performed more than twenty years ago. Most of the more recent studies have been seriously flawed in their design and/or execution because they neglected to account for important variables such as: pollutant exposures other than those from ambient air; the influence of personal activity on pollutant uptake; host responsiveness; and the separate contributions of recent transient peak exposures and long-term chronic exposures on the effects endpoints. For particulate pollutants, the influence of composition and size distribution has also received too little consideration. In order to address these deficiencies, research and methods development are needed on: indices for particulate exposures; identification of exposures relevant to the effects; improved indices of effects; acquisition of response data; identification of exposed populations; and identification of susceptible subgroups. Approaches to these needs are discussed, along with brief reviews of several recent studies that have focused on critical issues of concern, made the necessary efforts to characterize the relevant exposures of the populations being studied, and demonstrated human responses to ambient pollutants at current exposure levels. PMID:4085428

  3. Evaluation and Application of Alternative Air Pollution Exposure Metrics in Air Pollution Epidemiology Studies

    EPA Science Inventory

    ABSTRACT: Periodic review, revision and subsequent implementation of the National Ambient Air Quality Standards for criteria air pollutants rely upon various types of scientific air quality, exposure, toxicological dose-response and epidemiological information. Exposure assessmen...

  4. Air pollution exposure prediction approaches used in air pollution epidemiology studies

    EPA Science Inventory

    Epidemiological studies of the health effects of air pollution have traditionally relied upon surrogates of personal exposures, most commonly ambient concentration measurements from central-site monitors. However, this approach may introduce exposure prediction errors and miscla...

  5. Air pollution exposure prediction approaches used in air pollution epidemiology studies.

    PubMed

    Özkaynak, Halûk; Baxter, Lisa K; Dionisio, Kathie L; Burke, Janet

    2013-01-01

    Epidemiological studies of the health effects of outdoor air pollution have traditionally relied upon surrogates of personal exposures, most commonly ambient concentration measurements from central-site monitors. However, this approach may introduce exposure prediction errors and misclassification of exposures for pollutants that are spatially heterogeneous, such as those associated with traffic emissions (e.g., carbon monoxide, elemental carbon, nitrogen oxides, and particulate matter). We review alternative air quality and human exposure metrics applied in recent air pollution health effect studies discussed during the International Society of Exposure Science 2011 conference in Baltimore, MD. Symposium presenters considered various alternative exposure metrics, including: central site or interpolated monitoring data, regional pollution levels predicted using the national scale Community Multiscale Air Quality model or from measurements combined with local-scale (AERMOD) air quality models, hybrid models that include satellite data, statistically blended modeling and measurement data, concentrations adjusted by home infiltration rates, and population-based human exposure model (Stochastic Human Exposure and Dose Simulation, and Air Pollutants Exposure models) predictions. These alternative exposure metrics were applied in epidemiological applications to health outcomes, including daily mortality and respiratory hospital admissions, daily hospital emergency department visits, daily myocardial infarctions, and daily adverse birth outcomes. This paper summarizes the research projects presented during the symposium, with full details of the work presented in individual papers in this journal issue. PMID:23632992

  6. A growing role for gender analysis in air pollution epidemiology.

    PubMed

    Clougherty, Jane E

    2011-04-01

    Epidemiologic studies of air pollution effects on respiratory health report significant modification by sex, although results are not uniform. Importantly, it remains unclear whether modifications are attributable to socially derived gendered exposures, to sex-linked physiological differences, or to some interplay thereof. Gender analysis, which aims to disaggregate social from biological differences between males and females, may help to elucidate these possible sources of effect modification. Studies of children suggest stronger effects among boys in early life and among girls in later childhood. The qualitative review describes possible sources of difference in air pollution response between women and men, which may vary by life stage, coexposures, hormonal status, or other factors. The sources of observed effect modifications remain unclear, although gender analytic approaches may help to disentangle gender and sex differences in pollution response. A framework for incorporating gender analysis into environmental epidemiology is offered, along with several potentially useful methods from gender analysis. PMID:21584463

  7. Air Pollutants and Health: An Epidemiologic Approach

    ERIC Educational Resources Information Center

    Ember, Lois R.

    1977-01-01

    A ten year study, being conducted by the Harvard School of Public Health in six cities since 1974, is a survey of children and adults for the health effects of pollutant levels. The environment is being monitored for: (1) sulfur dioxide, (2) sulfates, and (3) respirable particulates. (BT)

  8. Complex mixtures and indoor air pollution: overview of epidemiologic methods.

    PubMed Central

    Weiss, N S

    1993-01-01

    The likelihood of an epidemiologic study correctly identifying an adverse health outcome associated with exposure to indoor air pollutants is increased if a) substantial variation exists in the frequency or level of exposure among study subjects otherwise at similar risk of the health outcome; b) the number of study subjects or study communities is large; c) the health outcome can be assessed with accuracy; d) relevant exposure levels can be measured with accuracy; e) an unbiased sample of exposed and nonexposed subjects is selected for study; and f) other determinants of the adverse health outcome can be measured. Nonetheless, given a strong enough impact of exposure to one pollutant or a mixture of pollutants on the risk of illness, it is possible for epidemiologic studies to discern a relation even if only some of the above circumstances are present. PMID:8206026

  9. Development and Evaluation of Alternative Metrics of Ambient Air Pollution Exposure for Use in Epidemiologic Studies

    EPA Science Inventory

    Population-based epidemiologic studies of air pollution have traditionally relied upon imperfect surrogates of personal exposures, such as area-wide ambient air pollution levels based on readily available outdoor concentrations from central monitoring sites. This practice may in...

  10. A Growing Role for Gender Analysis in Air Pollution Epidemiology

    PubMed Central

    Clougherty, Jane E.

    2010-01-01

    Objective Epidemiologic studies of air pollution effects on respiratory health report significant modification by sex, although results are not uniform. Importantly, it remains unclear whether modifications are attributable to socially derived gendered exposures, to sex-linked physiological differences, or to some interplay thereof. Gender analysis, which aims to disaggregate social from biological differences between males and females, may help to elucidate these possible sources of effect modification. Data sources and data extraction A PubMed literature search was performed in July 2009, using the terms “respiratory” and any of “sex” or “gender” or “men and women” or “boys and girls” and either “PM2.5” (particulate matter ≥ 2.5 μm in aerodynamic diameter) or “NO2” (nitrogen dioxide). I reviewed the identified studies, and others cited therein, to summarize current evidence of effect modification, with attention to authors’ interpretation of observed differences. Owing to broad differences in exposure mixes, outcomes, and analytic techniques, with few studies examining any given combination thereof, meta-analysis was not deemed appropriate at this time. Data synthesis More studies of adults report stronger effects among women, particularly for older persons or where using residential exposure assessment. Studies of children suggest stronger effects among boys in early life and among girls in later childhood. Conclusions The qualitative review describes possible sources of difference in air pollution response between women and men, which may vary by life stage, coexposures, hormonal status, or other factors. The sources of observed effect modifications remain unclear, although gender analytic approaches may help to disentangle gender and sex differences in pollution response. A framework for incorporating gender analysis into environmental epidemiology is offered, along with several potentially useful methods from gender analysis

  11. USE OF EMERGENCY ROOM PATIENT POPULATIONS IN AIR POLLUTION EPIDEMIOLOGY

    EPA Science Inventory

    The long-term objective of this project was the design and implementation of a particular epidemiological approach to investigation of ambient pollutant effects: the correlation of pollutant exposure with patterns of hospital emergency room utilization. The report covers the init...

  12. A Comparison of Exposure Metrics for Traffic-Related Air Pollutants: Application to Epidemiology Studies in Detroit, Michigan

    EPA Science Inventory

    Vehicles are major sources of air pollutant emissions, and individuals living near large roads endure high exposures and health risks associated with traffic-related air pollutants. Air pollution epidemiology, health risk, environmental justice, and transportation planning studi...

  13. Framing air pollution epidemiology in terms of population interventions, with applications to multi-pollutant modeling

    PubMed Central

    Snowden, Jonathan M.; Reid, Colleen E.; Tager, Ira B.

    2015-01-01

    Air pollution epidemiology continues moving toward the study of mixtures and multi-pollutant modeling. Simultaneously, there is a movement in epidemiology to estimate policy-relevant health effects that can be understood in reference to specific interventions. Scaling regression coefficients from a regression model by an interquartile range (IQR) is one common approach to presenting multi-pollutant health effect estimates. We are unaware of guidance on how to interpret these effect estimates as an intervention. To illustrate the issues of interpretability of IQR-scaled air pollution health effects, we analyzed how daily concentration changes in two air pollutants (NO2 and PM2.5; nitrogen dioxide and particulate matter with aerodynamic diameter ≤ 2.5μm) related to one another within two seasons (summer and winter), within three cities with distinct air pollution profiles (Burbank, California; Houston, Texas; and Pittsburgh, Pennsylvania). In each city-season, we examined how realistically IQR-scaling in multipollutant lag-1 time-series studies reflects a hypothetical intervention that is possible given the observed data. We proposed 2 causal conditions to explicitly link IQR-scaled effects to a clearly defined hypothetical intervention. Condition 1 specified that the index pollutant had to experience a daily concentration change of greater than one IQR, reflecting the notion that the IQR is an appropriate measure of variability between consecutive days. Condition 2 specified that the co-pollutant had to remain relatively constant. We found that in some city-seasons, there were very few instances in which these conditions were satisfied (e.g., 1 day in Pittsburgh during summer). We discuss the practical implications of IQR scaling and suggest alternative approaches to presenting multi-pollutant effects that are supported by empirical data. PMID:25643106

  14. RESPIRATORY EPIDEMIOLOGY OF HOUSEHOLD AIR POLLUTION EXPOSURES IN DEVELOPING COUNTRIES

    EPA Science Inventory

    Acute and chronic respiratory diseases impose a huge public health burden in the developing world. A large and growing body of scientific evidence indicates that household air pollution exposures contribute substantially to this burden. The most important source of indoor air p...

  15. "Development of Model-Based Air Pollution Exposure Metrics for use in Epidemiologic Studies"

    EPA Science Inventory

    Population-based epidemiological studies of air pollution have traditionally relied upon imperfect surrogates of personal exposures, such as area-wide ambient air pollution levels based on readily available concentrations from central monitoring sites. U.S. EPA in collaboration w...

  16. DEVELOPMENT OF MODEL-BASED AIR POLLUTION EXPOSURE METRICS FOR USE IN EPIDEMIOLOGIC STUDIES

    EPA Science Inventory

    Population-based epidemiological studies of air pollution have traditionally relied upon imperfect surrogates of personal exposures, such as area-wide ambient air pollution levels based on readily available concentrations from central monitoring sites. U.S. EPA in collaboration w...

  17. Epidemiological evidence for aggravation and promotion of COPD by acid air pollution

    SciTech Connect

    Dockery, D.W.; Speizer, F.E.

    1989-01-01

    The chapter discusses epidemiologic evidence for the role of acidic aerosols in the development and exacerbation of chronic obstructive pulmonary disease. The hypothesis that sulfuric acid was the most important component of the mix of pollutants responsible for classic air pollution episodes was first proposed more than 50 years ago. However, analyses of these episodes and more recent epidemiologic studies of lower level exposures are suggestive but not conclusive, primarily because of the limitations in technology available for measuring exposure.

  18. Panel discussion review: Session two - Interpretation of Observed Associations between Multiple Ambient Air Pollutants and Health Effects in Epidemiologic Analysis

    EPA Science Inventory

    Air pollution epidemiologic research has often utilized ambient air concentrations measured from centrally located monitors as a surrogate measure of exposure to these pollutants. Associations between these ambient concentrations and health outcomes such as lung function, hospita...

  19. Relation of air pollution with epidemiology of respiratory diseases in isfahan, Iran from 2005 to 2009

    PubMed Central

    Rashidi, Maasoumeh; Ramesht, Mohammad Hossein; Zohary, Moein; Poursafa, Parinaz; Kelishadi, Roya; Rashidi, Zeinab; Rouzbahani, Reza

    2013-01-01

    Background: National Institute of Environmental Health Sciences (NIEHS) scientists shows that long-term exposure to air pollutants increases the risk of respiratory diseases such as allergies, asthma, chronic obstructive pulmonary disease, and lung cancer. Children and the elderly are particularly vulnerable to the health effects of ozone, fine particles, and other airborne toxicants. Air pollution factors are considered as one of the underlying causes of respiratory diseases. This study aimed to determine the association of respiratory diseases documented in medical records and air pollution (Map distribution) of accumulation in Isfahan province, Iran. By plotting the prevalence and spatial distribution maps, important differences from different points can be observed. Materials and Methods: The geographic information system (GIS), pollutant standards index (PSI) measurements, and remote Sensing (RS) technology were used after entering data in the mapping information table; spatial distribution was mapped and distribution of Geographical Epidemiology of Respiratory Diseases in Isfahan province (Iran) was determined in this case study from 2005 to 2009. Results: Space with tracing the distribution of respiratory diseases was scattered based on the distribution of air pollution in the points is an important part of this type of diseases in Isfahan province where air pollution was more abundant. Conclusion: The findings of this study emphasis on the importance of preventing the exposure to air pollution, and to control air pollution product industries, to improve work environmental health, and to increase the health professionals and public knowledge in this regard. PMID:24523799

  20. Exposure prediction approaches used in air pollution epidemiology studies: Keyfindings and future recommendations

    EPA Science Inventory

    Many epidemiologic studies of the health effects of exposure to ambient air pollution use measurements from central-site monitors as their exposure estimate. However, measurements from central-site monitors may lack the spatial and temporal resolution required to capture exposure...

  1. EPIDEMIOLOGICAL EVIDENCE FOR AGGRAVATION AND PROMOTION OF COPD BY ACID AIR POLLUTION

    EPA Science Inventory

    This chapter discusses epidemiologic evidence for the role of acidic aerosols in the development and exacerbation of chronic obstructive pulmonary disease. The hypothesis that sulfuric acid was the most important component of the mix of pollutants responsible for classic air-poll...

  2. Application environmental epidemiology to vehicular air pollution and health effects research.

    PubMed

    Patil, Rajan R; Chetlapally, Satish Kumar; Bagvandas, M

    2015-01-01

    Vehicular pollution is one of the major contributors to the air pollution in urban areas and perhaps and accounts for the major share of anthropogenic green-house gases such as carbon dioxide, carbon monoxide, nitrogen oxides. Knowledge of human health risks related to environmental exposure to vehicular pollution is a current concern. Analyze the range health effects are attributed varied constituents of vehicular air pollution examine evidence for a causal association to specific health effect. In many instances scenario involves exposure to very low doses of putative agents for extended periods, sometimes the period could mean over a lifetime of an individual and yet may result in small increase in health risk that may be imperceptible. Secondary data analysis and literature review. In environmental exposures, traditional epidemiological approaches evaluating mortality and morbidity indicators display many limiting factors such as nonspecificity of biological effects latency time between exposure and magnitude of the effect. Long latency period between exposure and resultant disease, principally for carcinogenic effects and limitation of epidemiological studies for detecting small risk increments. The present paper discusses the methodological challenges in studying vehicular epidemiology and highlights issues that affect the validity of epidemiological studies in vehicular pollution. PMID:26023265

  3. Application environmental epidemiology to vehicular air pollution and health effects research

    PubMed Central

    Patil, Rajan R.; Chetlapally, Satish Kumar; Bagvandas, M.

    2015-01-01

    Vehicular pollution is one of the major contributors to the air pollution in urban areas and perhaps and accounts for the major share of anthropogenic green-house gases such as carbon dioxide, carbon monoxide, nitrogen oxides. Knowledge of human health risks related to environmental exposure to vehicular pollution is a current concern. Analyze the range health effects are attributed varied constituents of vehicular air pollution examine evidence for a causal association to specific health effect. In many instances scenario involves exposure to very low doses of putative agents for extended periods, sometimes the period could mean over a lifetime of an individual and yet may result in small increase in health risk that may be imperceptible. Secondary data analysis and literature review. In environmental exposures, traditional epidemiological approaches evaluating mortality and morbidity indicators display many limiting factors such as nonspecificity of biological effects latency time between exposure and magnitude of the effect. Long latency period between exposure and resultant disease, principally for carcinogenic effects and limitation of epidemiological studies for detecting small risk increments. The present paper discusses the methodological challenges in studying vehicular epidemiology and highlights issues that affect the validity of epidemiological studies in vehicular pollution. PMID:26023265

  4. A Review of Epidemiological Research on Adverse Neurological Effects of Exposure to Ambient Air Pollution.

    PubMed

    Xu, Xiaohui; Ha, Sandie Uyen; Basnet, Rakshya

    2016-01-01

    There is a growing body of epidemiological research reporting the neurological effects of ambient air pollution. We examined current evidence, identified the strengths and weaknesses of published epidemiological studies, and suggest future directions for research in this area. Studies were identified through a systematic search of online scientific databases, in addition to a manual search of the reference lists from the identified papers. Despite being a relatively new area of investigation, overall, there is mounting evidence implicating adverse effects of air pollution on neurobehavioral function in both adults and children. Further research is needed to expand our understanding of these relationships, including improvement in the accuracy of exposure assessments; focusing on specific toxicants and their relationships to specific health endpoints, such as neurodevelopmental disorders and neurodegenerative diseases; investigating the combined neurological effects of multiple air pollutants; and further exploration of genetic susceptibility for neurotoxicity of air pollution. In order to achieve these goals collaborative efforts are needed from multidisciplinary teams, including experts in toxicology, biostatistics, geographical science, epidemiology, and neurology. PMID:27547751

  5. A Review of Epidemiological Research on Adverse Neurological Effects of Exposure to Ambient Air Pollution

    PubMed Central

    Xu, Xiaohui; Ha, Sandie Uyen; Basnet, Rakshya

    2016-01-01

    There is a growing body of epidemiological research reporting the neurological effects of ambient air pollution. We examined current evidence, identified the strengths and weaknesses of published epidemiological studies, and suggest future directions for research in this area. Studies were identified through a systematic search of online scientific databases, in addition to a manual search of the reference lists from the identified papers. Despite being a relatively new area of investigation, overall, there is mounting evidence implicating adverse effects of air pollution on neurobehavioral function in both adults and children. Further research is needed to expand our understanding of these relationships, including improvement in the accuracy of exposure assessments; focusing on specific toxicants and their relationships to specific health endpoints, such as neurodevelopmental disorders and neurodegenerative diseases; investigating the combined neurological effects of multiple air pollutants; and further exploration of genetic susceptibility for neurotoxicity of air pollution. In order to achieve these goals collaborative efforts are needed from multidisciplinary teams, including experts in toxicology, biostatistics, geographical science, epidemiology, and neurology. PMID:27547751

  6. Epidemiologic evidence for asthma and exposure to air toxics: linkages between occupational, indoor, and community air pollution research.

    PubMed Central

    Delfino, Ralph J

    2002-01-01

    Outdoor ambient air pollutant exposures in communities are relevant to the acute exacerbation and possibly the onset of asthma. However, the complexity of pollutant mixtures and etiologic heterogeneity of asthma has made it difficult to identify causal components in those mixtures. Occupational exposures associated with asthma may yield clues to causal components in ambient air pollution because such exposures are often identifiable as single-chemical agents (e.g., metal compounds). However, translating occupational to community exposure-response relationships is limited. Of the air toxics found to cause occupational asthma, only formaldehyde has been frequently investigated in epidemiologic studies of allergic respiratory responses to indoor air, where general consistency can be shown despite lower ambient exposures. The specific volatile organic compounds (VOCs) identified in association with occupational asthma are generally not the same as those in studies showing respiratory effects of VOC mixtures on nonoccupational adult and pediatric asthma. In addition, experimental evidence indicates that airborne polycyclic aromatic hydrocarbon (PAH) exposures linked to diesel exhaust particles (DEPs) have proinflammatory effects on airways, but there is insufficient supporting evidence from the occupational literature of effects of DEPs on asthma or lung function. In contrast, nonoccupational epidemiologic studies have frequently shown associations between allergic responses or asthma with exposures to ambient air pollutant mixtures with PAH components, including black smoke, high home or school traffic density (particularly truck traffic), and environmental tobacco smoke. Other particle-phase and gaseous co-pollutants are likely causal in these associations as well. Epidemiologic research on the relationship of both asthma onset and exacerbation to air pollution is needed to disentangle effects of air toxics from monitored criteria air pollutants such as particle mass

  7. [Urban particulate air pollution: from epidemiology to health impact in public health].

    PubMed

    Filleul, L; Medina, S; Cassadou, S

    2003-10-01

    Major air pollution accidents which occurred in the 1950s led to public awareness of the health hazards involved. Since that period, levels of air pollution have decreased, but several studies conducted in North America and Europe indicate that particulate air pollution is linked to increased cardiorespiratory morbidity and mortality. Despite this evidence, several questions were raised concerning the interpretation of the results (threshold effect, harvesting effect and biological plausibility). The aim of this review is to present the link between epidemiological findings and their use in health impact assessment. We review the main causal criteria applied to epidemiology in light of scientific evidence currently available. Some causality criteria are more important than others, but they all support the causal nature of the relationship between air pollution and health, and thus justify the feasibility of health impact assessment calculations. Recent studies on relative risk assessment show that even if the risk linked to worsening air quality is low, public health consequences are high. Such information must be made accessible to policy makers and the population in general so that, together with the public health workers, they can all contribute to improving air quality and health in their communities. PMID:14657799

  8. Exposure prediction approaches used in air pollution epidemiology studies: Key findings and future recommendations

    PubMed Central

    Baxter, Lisa K.; Dionisio, Kathie L.; Burke, Janet; Sarnat, Stefanie Ebelt; Sarnat, Jeremy A.; Hodas, Natasha; Rich, David Q.; Turpin, Barbara J.; Jones, Rena R.; Mannshardt, Elizabeth; Kumar, Naresh; Beevers, Sean D.; Özkaynak, Halûk

    2014-01-01

    Many epidemiologic studies of the health effects of exposure to ambient air pollution use measurements from central-site monitors as their exposure estimate. However, measurements from central-site monitors may lack the spatial and temporal resolution required to capture exposure variability in a study population, thus resulting in exposure error and biased estimates. Articles in this dedicated issue examine various approaches to predict or assign exposures to ambient pollutants. These methods include: combining existing central-site pollution measurements with local- and/or regional-scale air quality models to create new or “hybrid” models for pollutant exposure estimates, and using exposure models to account for factors such as infiltration of pollutants indoors and human activity patterns. Key findings from these articles are summarized to provide lessons learned and recommendations for additional research on improving exposure estimation approaches for future epidemiological studies. In summary, when compared to use of central-site monitoring data, the enhanced spatial resolution of air quality or exposure models can have an impact on resultant health effect estimates, especially for pollutants derived from local sources such as traffic (e.g. EC, CO, and NOx). In addition, the optimal exposure estimation approach also depends upon the epidemiological study design. We recommend that future research develop pollutant-specific infiltration data (including for PM species), and improve existing data on human time-activity patterns, and exposure to local source (e.g. traffic), in order to enhance human exposure modeling estimates. We also recommend comparing how various approaches to exposure estimation characterize relationships between multiple pollutants in time and space, and investigating the impact of improved exposure estimates in chronic health studies. PMID:24084756

  9. Overview and Evaluation of Alternative Air Quality ExposureMetrics Used in Recent Air Pollution Epidemiological Studies

    EPA Science Inventory

    This poster presents selected results from a few of these studies conducted and provides a summary of key findings and lessons learned and recommendations, in order to improve the use of enhanced exposure metrics during future epidemiological studies of air pollution.

  10. Epidemiology of fine particulate air pollution and human health: biologic mechanisms and who's at risk?

    PubMed Central

    Pope, C A

    2000-01-01

    This article briefly summarizes the epidemiology of the health effects of fine particulate air pollution, provides an early, somewhat speculative, discussion of the contribution of epidemiology to evaluating biologic mechanisms, and evaluates who's at risk or is susceptible to adverse health effects. Based on preliminary epidemiologic evidence, it is speculated that a systemic response to fine particle-induced pulmonary inflammation, including cytokine release and altered cardiac autonomic function, may be part of the pathophysiologic mechanisms or pathways linking particulate pollution with cardiopulmonary disease. The elderly, infants, and persons with chronic cardiopulmonary disease, influenza, or asthma are most susceptible to mortality and serious morbidity effects from short-term acutely elevated exposures. Others are susceptible to less serious health effects such as transient increases in respiratory symptoms, decreased lung function, or other physiologic changes. Chronic exposure studies suggest relatively broad susceptibility to cumulative effects of long-term repeated exposure to fine particulate pollution, resulting in substantive estimates of population average loss of life expectancy in highly polluted environments. Additional knowledge is needed about the specific pollutants or mix of pollutants responsible for the adverse health effects and the biologic mechanisms involved. PMID:10931790

  11. Air Pollution

    MedlinePlus

    Air pollution is a mixture of solid particles and gases in the air. Car emissions, chemicals from factories, dust, ... a gas, is a major part of air pollution in cities. When ozone forms air pollution, it's ...

  12. Air Pollution

    MedlinePlus

    Air pollution is a mixture of solid particles and gases in the air. Car emissions, chemicals from factories, ... Ozone, a gas, is a major part of air pollution in cities. When ozone forms air pollution, it's ...

  13. Framing air pollution epidemiology in terms of population interventions, with applications to multipollutant modeling.

    PubMed

    Snowden, Jonathan M; Reid, Colleen E; Tager, Ira B

    2015-03-01

    Air pollution epidemiology continues moving toward the study of mixtures and multipollutant modeling. Simultaneously, there is a movement in epidemiology to estimate policy-relevant health effects that can be understood in reference to specific interventions. Scaling regression coefficients from a regression model by an interquartile range (IQR) is one common approach to presenting multipollutant health effect estimates. We are unaware of guidance on how to interpret these effect estimates as an intervention. To illustrate the issues of interpretability of IQR-scaled air pollution health effects, we analyzed how daily concentration changes in 2 air pollutants (nitrogen dioxide and particulate matter with aerodynamic diameter ≤ 2.5 μm) related to one another within 2 seasons (summer and winter), within 3 cities with distinct air pollution profiles (Burbank, California; Houston, Texas; and Pittsburgh, Pennsylvania). In each city season, we examined how realistically IQR scaling in multipollutant lag-1 time-series studies reflects a hypothetical intervention that is possible given the observed data. We proposed 2 causal conditions to explicitly link IQR-scaled effects to a clearly defined hypothetical intervention. Condition 1 specified that the index pollutant had to experience a daily concentration change of greater than 1 IQR, reflecting the notion that the IQR is an appropriate measure of variability between consecutive days. Condition 2 specified that the copollutant had to remain relatively constant. We found that in some city seasons, there were very few instances in which these conditions were satisfied (eg, 1 day in Pittsburgh during summer). We discuss the practical implications of IQR scaling and suggest alternative approaches to presenting multipollutant effects that are supported by empirical data. PMID:25643106

  14. Assessment of the epidemiological data relating lung cancer to air pollution.

    PubMed Central

    Speizer, F E

    1983-01-01

    The epidemiological data linking air pollution and lung cancer are derived from statistical associations concerning rates of cancer among urban and rural residents, migrant studies and studies of occupational groups exposed to effluents from fossil fuel combinations. Few, if any of these studies, are adequately adjusted for both relatively simple measures of cigarette smoking or the potentially more subtle effects of the duration of smoking. Because urbanization and industrial sources of air pollution correspond chronologically with the major increases in cigarette smoking, it is not likely that the specific attributable risk to each component can be adequately assessed. Interactions between cigarette smoking and specific air pollutants, similar to those seen between cigarette smoking and asbestos and or radiation, may be occurring. Considering the various estimates made over the last 25 years, it is likely that the effect of air pollution on lung cancer is something greater than zero; however, it is unlikely that the estimate exceeds 2% of all lung cancers or 5/100,000 cases in urban males. Thus, the effect on all cancers is likely to be less than 1% of all cases. PMID:6337830

  15. Air pollution epidemiologic studies in South Africa--need for freshening up.

    PubMed

    Wichmann, Janine; Voyi, Kuku V V

    2005-01-01

    The results of epidemiologic studies obtained in developed countries cannot be extrapolated with complete confidence to developing countries. The objectives of this review were to examine the evidence from local studies for associations between air pollution and adverse health along with a critical review for methodologic limitations. The literature search strategy and selection criteria involved a MEDLINE search up to June 2005. Of 267 journal articles found, 14 focused on air pollution epidemiology (excluding active smoking and internal dose as a proxy for health outcomes). Two studies were also located by word of mouth or through the references from the selected studies. The local studies provide some evidence of an association with a range of serious and common health problems. No study established an exposure-response curve for the criteria pollutants carbon monoxide, sulfur dioxide, nitrogen oxides, lead, and ozone. Therefore, using the results of such studies in risk-assessment is impossible. The studies were fraught with systematic and random errors, which limit their validity and precision. We recommend conducting a quantitative intervention study with an analytical study design in all major cities in the countries where residents are still using dirty fuels for cooking, lighting, and space heating. Future studies must involve national and international multidisciplinary stakeholders and must be planned well in advance. PMID:16422348

  16. The effects of outdoor air pollution on the respiratory health of Canadian children: A systematic review of epidemiological studies

    PubMed Central

    Rodriguez-Villamizar, Laura A; Magico, Adam; Osornio-Vargas, Alvaro; Rowe, Brian H

    2015-01-01

    BACKGROUND: Outdoor air pollution is a global problem with serious effects on human health, and children are considered to be highly susceptible to the effects of air pollution. OBJECTIVE: To conduct a comprehensive and updated systematic review of the literature reporting the effects of outdoor air pollution on the respiratory health of children in Canada. METHODS: Searches of four electronic databases between January 2004 and November 2014 were conducted to identify epidemiological studies evaluating the effect of exposure to outdoor air pollutants on respiratory symptoms, lung function measurements and the use of health services due to respiratory conditions in Canadian children. The selection process and quality assessment, using the Newcastle-Ottawa Scale, were conducted independently by two reviewers. RESULTS: Twenty-seven studies that were heterogeneous with regard to study design, population, respiratory outcome and air pollution exposure were identified. Overall, the included studies reported adverse effects of outdoor air pollution at concentrations that were below Canadian and United States standards. Heterogeneous effects of air pollutants were reported according to city, sex, socioeconomic status and seasonality. The present review also describes trends in research related to the effect of air pollution on Canadian children over the past 25 years. CONCLUSION: The present study reconfirms the adverse effects of outdoor air pollution on the respiratory health of children in Canada. It will help researchers, clinicians and environmental health authorities identify the available evidence of the adverse effect of outdoor air pollution, research gaps and the limitations for further research. PMID:25961280

  17. METHODS DEVELOPMENT FOR ASSESSING AIR POLLUTION CONTROL BENEFITS. VOLUME I. EXPERIMENTS IN THE ECONOMICS OF AIR POLLUTION EPIDEMIOLOGY

    EPA Science Inventory

    The volume employs the analytical and empirical methods of economics to develop hypotheses on disease etiologies and to value labor productivity and consumer losses due to air pollution-induced mortality and morbidity. In the mortality work, 1970 city-wide mortality rates for maj...

  18. AIR POLLUTION EPIDEMIOLOGY: CAN INFORMATION BE OBTAINED FROM THE VARIATIONS IN SIGNIFICANCE AND RISK AS A FUNCTION OF DAYS AFTER EXPOSURE (LAG STRUCTURE)?

    EPA Science Inventory

    Determine if analysis of lag structure from time series epidemiology, using gases, particles, and source factor time series, can contribute to understanding the relationships among various air pollution indicators. Methods: Analyze lag structure from an epidemiologic study of ca...

  19. Air Pollution.

    ERIC Educational Resources Information Center

    Gilpin, Alan

    A summary of one of our most pressing environmental problems, air pollution, is offered in this book by the Director of Air Pollution Control for the Queensland (Australia) State Government. Discussion of the subject is not restricted to Queensland or Australian problems and policies, however, but includes analysis of air pollution the world over.…

  20. Measurement error in two-stage analyses, with application to air pollution epidemiology

    PubMed Central

    Szpiro, Adam A.; Paciorek, Christopher J.

    2014-01-01

    Summary Public health researchers often estimate health effects of exposures (e.g., pollution, diet, lifestyle) that cannot be directly measured for study subjects. A common strategy in environmental epidemiology is to use a first-stage (exposure) model to estimate the exposure based on covariates and/or spatio-temporal proximity and to use predictions from the exposure model as the covariate of interest in the second-stage (health) model. This induces a complex form of measurement error. We propose an analytical framework and methodology that is robust to misspecification of the first-stage model and provides valid inference for the second-stage model parameter of interest. We decompose the measurement error into components analogous to classical and Berkson error and characterize properties of the estimator in the second-stage model if the first-stage model predictions are plugged in without correction. Specifically, we derive conditions for compatibility between the first- and second-stage models that guarantee consistency (and have direct and important real-world design implications), and we derive an asymptotic estimate of finite-sample bias when the compatibility conditions are satisfied. We propose a methodology that (1) corrects for finite-sample bias and (2) correctly estimates standard errors. We demonstrate the utility of our methodology in simulations and an example from air pollution epidemiology. PMID:24764691

  1. Air Pollution.

    ERIC Educational Resources Information Center

    Fox, Donald L.

    1989-01-01

    Materials related to air pollution are reviewed for the period January 1987, to October 1988. The topics are pollution monitoring, air pollution, and environmental chemistry. The organization consists of two major analytical divisions: (1) gaseous methods; and (2) aerosol and particulate methods. (MVL)

  2. Epidemiology and air pollution. A report of the Committee on the Epidemiology of Air Pollutants, Board on Toxicology and Environmental Health Hazards, Commission on Life Sciences, National Research Council

    SciTech Connect

    Not Available

    1985-01-01

    This report examines the role of epidemiology in the study of the health effects of air pollution. The four health effects of concern in the report art acute respiratory infection, chronic obstructive pulmonary disease, asthma and lung cancer. The five types of pollution said to be of continuing concern are woodsmoke, nitrogen oxides, persistant ozone and acid aerosols, episodic ozone and acid aerosol haze and radon. The advantages of using epidemiological studies are discussed. They include: direct determination of public health problems and estimation of their magnitude; evaluation of the impact of decreases in exposure; and defining characteristics of the problem that can guide intervention even before the mechanics are understood.

  3. The importance of the exposure metric in air pollution epidemiology studies: When does it matter, and why?

    EPA Science Inventory

    Exposure error in ambient air pollution epidemiologic studies may introduce bias and/or attenuation of the health risk estimate, reduce statistical significance, and lower statistical power. Alternative exposure metrics are increasingly being used in place of central-site measure...

  4. Effect of particulate matter air pollution on C-reactive protein: a review of epidemiologic studies

    PubMed Central

    Li, Yanli; Rittenhouse-Olson, Kate; L.Scheider, William; Mu, Lina

    2013-01-01

    Inflammatory response is implicated as a biologic mechanism that links particulate matter (PM) air pollution with health effects. C-reactive protein (CRP), an important acute-phase reactant with profound proinflammatory properties, is used clinically as an indicator of the presence and intensity of inflammation. In vitro and in vivo animal studies suggest that CRP levels increase in response to PM exposure, but there was no consistency in epidemiologic studies. Herein, a systematic review was conducted to examine the association between PM exposure and serum CRP levels in humans. Elevated CRP levels were consistently found among children, and CRP elevations were also observed among healthy adults, albeit requiring higher peak levels of PM exposure. PM-induced CRP responses were not consistently found in adults with chronic inflammatory conditions, perhaps because of the use of anti-inflammatory medications in this population. Of the eight examined randomized trials, only one trial with a longer intervention period supported the effect of PM exposure on CRP concentrations. To provide conclusive evidence, further epidemiologic studies are needed to better quantify the magnitude of CRP level changes in response to PM with well-defined study populations and better control of various confounding factors. PMID:23023922

  5. Development of outdoor exposure model of traffic-related air pollution for epidemiologic research in Japan.

    PubMed

    Kanda, Isao; Ohara, Toshimasa; Nataami, Taro; Nitta, Hiroshi; Tamura, Kenji; Hasegawa, Shuichi; Shima, Masayuki; Nakai, Satoshi; Sakamoto, Kazuhiko; Yokota, Hisashi

    2013-01-01

    We developed an exposure estimation model for an epidemiological study on the effect of traffic-related air pollutants on respiratory diseases. The model estimates annual average outdoor concentration of nitrogen oxides (NOx) and elemental carbon (EC). The model is composed of three nested plume dispersion type submodels treating different spatial scales from a few meters to tens of kilometers. The emissions from road traffic was estimated at high spatial resolution along the paths of roads taking into account the effects of individual building shape and traffic signals to secure accuracy near trunk roads where most of the subjects of the epidemiological study resided. Model performance was confirmed by field measurements at permanent local government stations and purpose-built temporary stations; the latter supplemented roadside monitoring points and provided EC concentrations, which are not measured routinely. We infer that EC emissions were underestimated by using the available database because there were significant contributions to EC concentrations from sources that did not emit much NOx. An adjustment concentration yielded good agreement between model estimates and field measurements. PMID:23715083

  6. Identifying exposure disparities in air pollution epidemiology specific to adverse birth outcomes

    NASA Astrophysics Data System (ADS)

    Geer, Laura A.

    2014-10-01

    More than 147 million people in the US live in areas where pollutant levels are above regulatory limits and pose a risk to health. Most of the vast network of air pollutant monitors in the US are located in places with higher pollution levels and a higher density of pollutant sources (e.g., point sources from industrial pollution). Vulnerable populations are more likely to live closer to pollutant sources, and thus closer to pollutant monitors. These differential exposures have an impact on maternal and child health; maternal air pollutant exposures have been linked to adverse outcomes such as preterm birth and infant low birth weight. Several studies are highlighted that address methodological approaches in the study of air pollution and health disparities.

  7. Air Pollution.

    EPA Science Inventory

    Air quality is affected by many types of pollutants that are emitted from various sources, including stationary and mobile. These sources release both criteria and hazardous air pollutants, which cause health effects, ecological harm, and material damage. They are generally categ...

  8. Criteria air pollutants and toxic air pollutants.

    PubMed Central

    Suh, H H; Bahadori, T; Vallarino, J; Spengler, J D

    2000-01-01

    This review presents a brief overview of the health effects and exposures of two criteria pollutants--ozone and particulate matter--and two toxic air pollutants--benzene and formaldehyde. These pollutants were selected from the six criteria pollutants and from the 189 toxic air pollutants on the basis of their prevalence in the United States, their physicochemical behavior, and the magnitude of their potential health threat. The health effects data included in this review primarily include results from epidemiologic studies; however, some findings from animal studies are also discussed when no other information is available. Health effects findings for each pollutant are related in this review to corresponding information about outdoor, indoor, and personal exposures and pollutant sources. Images Figure 3 Figure 8 Figure 9 PMID:10940240

  9. Imputation method for lifetime exposure assessment in air pollution epidemiologic studies

    PubMed Central

    2013-01-01

    Background Environmental epidemiology, when focused on the life course of exposure to a specific pollutant, requires historical exposure estimates that are difficult to obtain for the full time period due to gaps in the historical record, especially in earlier years. We show that these gaps can be filled by applying multiple imputation methods to a formal risk equation that incorporates lifetime exposure. We also address challenges that arise, including choice of imputation method, potential bias in regression coefficients, and uncertainty in age-at-exposure sensitivities. Methods During time periods when parameters needed in the risk equation are missing for an individual, the parameters are filled by an imputation model using group level information or interpolation. A random component is added to match the variance found in the estimates for study subjects not needing imputation. The process is repeated to obtain multiple data sets, whose regressions against health data can be combined statistically to develop confidence limits using Rubin’s rules to account for the uncertainty introduced by the imputations. To test for possible recall bias between cases and controls, which can occur when historical residence location is obtained by interview, and which can lead to misclassification of imputed exposure by disease status, we introduce an “incompleteness index,” equal to the percentage of dose imputed (PDI) for a subject. “Effective doses” can be computed using different functional dependencies of relative risk on age of exposure, allowing intercomparison of different risk models. To illustrate our approach, we quantify lifetime exposure (dose) from traffic air pollution in an established case–control study on Long Island, New York, where considerable in-migration occurred over a period of many decades. Results The major result is the described approach to imputation. The illustrative example revealed potential recall bias, suggesting that regressions

  10. Air Pollution

    MedlinePlus

    ... tobacco smoke. How is air pollution linked to climate change? While climate change is a global process, it ... ozone levels are also a concern. Impacts of Climate Change on Human Health in the United States: A ...

  11. [Air pollution].

    PubMed

    Bauters, Christophe; Bauters, Gautier

    2016-01-01

    Short-term exposure to particulate matter (PM) air pollution is associated with an increased cardiovascular mortality. Chronic exposure to PM is also associated with cardiovascular risk. Myocardial infarction and heart failure are the most common cardiovascular events associated with PM pollution. The pathophysiological mechanisms related to PM pollution are inflammation, thrombosis, vasomotion abnormalities, progression of atherosclerosis, increased blood pressure, and cardiac remodeling. A decrease in PM exposure may be particularly beneficial in subjects with a high cardiovascular risk. PMID:26547674

  12. Air Pollution.

    ERIC Educational Resources Information Center

    Scorer, Richard S.

    The purpose of this book is to describe the basic mechanisms whereby pollution is transported and diffused in the atmosphere. It is designed to give practitioners an understanding of basic mechanics and physics so they may have a correct basis on which to formulate their decisions related to practical air pollution control problems. Since many…

  13. Spatial and temporal associations of road traffic noise and air pollution in London: Implications for epidemiological studies.

    PubMed

    Fecht, Daniela; Hansell, Anna L; Morley, David; Dajnak, David; Vienneau, Danielle; Beevers, Sean; Toledano, Mireille B; Kelly, Frank J; Anderson, H Ross; Gulliver, John

    2016-03-01

    Road traffic gives rise to noise and air pollution exposures, both of which are associated with adverse health effects especially for cardiovascular disease, but mechanisms may differ. Understanding the variability in correlations between these pollutants is essential to understand better their separate and joint effects on human health. We explored associations between modelled noise and air pollutants using different spatial units and area characteristics in London in 2003-2010. We modelled annual average exposures to road traffic noise (LAeq,24h, Lden, LAeq,16h, Lnight) for ~190,000 postcode centroids in London using the UK Calculation of Road Traffic Noise (CRTN) method. We used a dispersion model (KCLurban) to model nitrogen dioxide, nitrogen oxide, ozone, total and the traffic-only component of particulate matter ≤2.5μm and ≤10μm. We analysed noise and air pollution correlations at the postcode level (~50 people), postcodes stratified by London Boroughs (~240,000 people), neighbourhoods (Lower layer Super Output Areas) (~1600 people), 1km grid squares, air pollution tertiles, 50m, 100m and 200m in distance from major roads and by deprivation tertiles. Across all London postcodes, we observed overall moderate correlations between modelled noise and air pollution that were stable over time (Spearman's rho range: |0.34-0.55|). Correlations, however, varied considerably depending on the spatial unit: largest ranges were seen in neighbourhoods and 1km grid squares (both Spearman's rho range: |0.01-0.87|) and was less for Boroughs (Spearman's rho range: |0.21-0.78|). There was little difference in correlations between exposure tertiles, distance from road or deprivation tertiles. Associations between noise and air pollution at the relevant geographical unit of analysis need to be carefully considered in any epidemiological analysis, in particular in complex urban areas. Low correlations near roads, however, suggest that independent effects of road noise and

  14. Point: Clarifying Policy Evidence With Potential-Outcomes Thinking—Beyond Exposure-Response Estimation in Air Pollution Epidemiology

    PubMed Central

    Zigler, Corwin Matthew; Dominici, Francesca

    2014-01-01

    The regulatory environment surrounding policies to control air pollution warrants a new type of epidemiologic evidence. Whereas air pollution epidemiology has typically informed policies with estimates of exposure-response relationships between pollution and health outcomes, these estimates alone cannot support current debates surrounding the actual health effects of air quality regulations. We argue that directly evaluating specific control strategies is distinct from estimating exposure-response relationships and that increased emphasis on estimating effects of well-defined regulatory interventions would enhance the evidence that supports policy decisions. Appealing to similar calls for accountability assessment of whether regulatory actions impact health outcomes, we aim to sharpen the analytic distinctions between studies that directly evaluate policies and those that estimate exposure-response relationships, with particular focus on perspectives for causal inference. Our goal is not to review specific methodologies or studies, nor is it to extoll the advantages of “causal” versus “associational” evidence. Rather, we argue that potential-outcomes perspectives can elevate current policy debates with more direct evidence of the extent to which complex regulatory interventions affect health. Augmenting the existing body of exposure-response estimates with rigorous evidence of the causal effects of well-defined actions will ensure that the highest-level epidemiologic evidence continues to support regulatory policies. PMID:25399414

  15. Point: clarifying policy evidence with potential-outcomes thinking--beyond exposure-response estimation in air pollution epidemiology.

    PubMed

    Zigler, Corwin Matthew; Dominici, Francesca

    2014-12-15

    The regulatory environment surrounding policies to control air pollution warrants a new type of epidemiologic evidence. Whereas air pollution epidemiology has typically informed policies with estimates of exposure-response relationships between pollution and health outcomes, these estimates alone cannot support current debates surrounding the actual health effects of air quality regulations. We argue that directly evaluating specific control strategies is distinct from estimating exposure-response relationships and that increased emphasis on estimating effects of well-defined regulatory interventions would enhance the evidence that supports policy decisions. Appealing to similar calls for accountability assessment of whether regulatory actions impact health outcomes, we aim to sharpen the analytic distinctions between studies that directly evaluate policies and those that estimate exposure-response relationships, with particular focus on perspectives for causal inference. Our goal is not to review specific methodologies or studies, nor is it to extoll the advantages of "causal" versus "associational" evidence. Rather, we argue that potential-outcomes perspectives can elevate current policy debates with more direct evidence of the extent to which complex regulatory interventions affect health. Augmenting the existing body of exposure-response estimates with rigorous evidence of the causal effects of well-defined actions will ensure that the highest-level epidemiologic evidence continues to support regulatory policies. PMID:25399414

  16. Air Pollution Exposure

    PubMed Central

    Balmes, John R.; Collard, Harold R.

    2015-01-01

    Air pollution exposure is a well-established risk factor for several adverse respiratory outcomes, including airways diseases and lung cancer. Few studies have investigated the relationship between air pollution and interstitial lung disease (ILD) despite many forms of ILD arising from environmental exposures. There are potential mechanisms by which air pollution could cause, exacerbate, or accelerate the progression of certain forms of ILD via pulmonary and systemic inflammation as well as oxidative stress. This article will review the current epidemiologic and translational data supporting the plausibility of this relationship and propose a new conceptual framework for characterizing novel environmental risk factors for these forms of lung disease. PMID:25846532

  17. Temporal aspects of air pollutant measures in epidemiologic analysis: a simulation study

    NASA Astrophysics Data System (ADS)

    White, Laura F.; Yu, Jeffrey; Jerrett, Michael; Coogan, Patricia

    2016-01-01

    Numerous observational studies have assessed the association between ambient air pollution and chronic disease incidence, but there is no uniform approach to create an exposure metric that captures the variability in air pollution through time and determines the most relevant exposure window. The purpose of the present study was to assess ways of modeling exposure to air pollution in relation to incident hypertension. We simulated data on incident hypertension to assess the performance of six air pollution exposure metrics, using characteristics from the Black Women’s Health Study. Each metric made different assumptions about how to incorporate time trends in pollutant data, and the most relevant window of exposure. We use observed values for particulate matter ≤2.5 microns (PM2.5) for this cohort to create the six exposure metrics and fit Cox proportional hazards models to the simulated data using the six metrics. The optimal exposure metric depends on the underlying association between PM2.5 and disease, which is unknown. Metrics that incorporate exposure information from multiple years tend to be more robust and suffer from less bias. This study provides insight into factors that influence the metric used to quantifying exposure to PM2.5 and suggests the need for careful sensitivity analyses.

  18. Temporal aspects of air pollutant measures in epidemiologic analysis: a simulation study

    PubMed Central

    White, Laura F; Yu, Jeffrey; Jerrett, Michael; Coogan, Patricia

    2016-01-01

    Numerous observational studies have assessed the association between ambient air pollution and chronic disease incidence, but there is no uniform approach to create an exposure metric that captures the variability in air pollution through time and determines the most relevant exposure window. The purpose of the present study was to assess ways of modeling exposure to air pollution in relation to incident hypertension. We simulated data on incident hypertension to assess the performance of six air pollution exposure metrics, using characteristics from the Black Women’s Health Study. Each metric made different assumptions about how to incorporate time trends in pollutant data, and the most relevant window of exposure. We use observed values for particulate matter ≤2.5 microns (PM2.5) for this cohort to create the six exposure metrics and fit Cox proportional hazards models to the simulated data using the six metrics. The optimal exposure metric depends on the underlying association between PM2.5 and disease, which is unknown. Metrics that incorporate exposure information from multiple years tend to be more robust and suffer from less bias. This study provides insight into factors that influence the metric used to quantifying exposure to PM2.5 and suggests the need for careful sensitivity analyses. PMID:26791428

  19. [Prospective one-year epidemiologic longitudinal study of air pollutants and the incidence of croup].

    PubMed

    Rebmann, H; Hub, J; Huenges, R; Neu, A; Grunert, D; Horn, H; Döller, G; Döller, P C; Gerth, H J; Wichmann, H E

    1988-07-01

    Among a population of 18,175 children below 7 years of age in medium sized towns and rural areas in south-western Germany 552 (3.03%) cases of croup were registered during a 12 months period in 1984-85 by their physicians. Distributions according to months, sex and age at the onset of the disease were the same as in other recent investigations: The level of the air-pollution measured (SO2, NOx, CO, CO2, ozone and dust) was low (highest monthly means in microgram/m3: SO2 88, NO2 73, NO 119, dust 41). There was no relevant influence of the degree of air pollution on croup-frequency. The rise of croup-frequency shortly after a period of several days of higher pollution was accompanied by an influenza epidemic as proved by virus isolations. PMID:3264886

  20. Air Pollution

    PubMed Central

    Clifton, Marjorie

    1964-01-01

    Dr Marjorie Clifton describes the classification of gaseous and nongaseous constituents of air pollution and then outlines the methods of measuring these. The National Survey embraced 150 towns of all sizes throughout England and Wales and provided data on smoke and sulphur dioxide in relation to climate, topography, industrialization, population density, fuel utilization and urban development. Dr W C Turner discusses the relationship between air pollution and mortality from respiratory conditions, and particularly the incidence of chronic bronchitis. He postulates a theory that such respiratory conditions arise as an allergy to the spores of certain moulds, spore formation being encouraged by the air humidity in Greatv Britain and overcrowded and damp living conditions. He describes the results of a twenty-week study undertaken in 1962-3, showing associations between respiratory disease and levels of air pollution. Dr Stuart Carne undertook a survey in general practice to plot the patterns of respiratory illness in London during the winter of 1962-3. There were two peaks of respiratory illnesses coinciding with the fog at the beginning of December and the freeze-up from the end of December until the beginning of March. PMID:14178955

  1. Measurement of acidic aerosol species in eastern Europe: implications for air pollution epidemiology.

    PubMed Central

    Brauer, M; Dumyahn, T S; Spengler, J D; Gutschmidt, K; Heinrich, J; Wichmann, H E

    1995-01-01

    A large number of studies have indicated associations between particulate air pollution and adverse health outcomes. Wintertime air pollution in particular has been associated with increased mortality. Identification of causal constituents of inhalable particulate matter has been elusive, although one candidate has been the acidity of the aerosol. Here we report measurements of acidic aerosol species made for approximately 1.5 years in Erfurt, Germany, and Sokolov, Czech Republic. In both locations, the burning of high-sulfur coal is the primary source of ambient air pollution. Twenty-four-hour average measurements were made for PM10, [particulate matter with an aerodynamic diameter (da) < or = 10 microns], as well as fine particle (da < 2.5 microns) H+ and SO4(2-) for the entire study. Additionally, separate day and night measurements of fine particle H+, SO4(2-), NO3-, and NH4+ and the gases, SO2, HNO3, HONO, and NH3 were collected with an annular denuder/filter pack system over a 7-month (late winter-summer) period with additional measurements during pollution episodes the following winter. At both sites, 24-hr SO2 (mean concentrations of 52 micrograms/m3, with peak levels of > 585 micrograms/m3) and PM10 (mean concentration 60 micrograms m3) concentrations were quite high. However, aerosol SO4(2-) concentrations (mean concentration of approximately 10 micrograms/m3) were not as great as expected given the high SO2 concentrations, and acidity was very low (mean concentration of < 1 microgram/m3, with peak levels of only 7 micrograms/m3). Low acidity is likely to be the result of NH3 neutralization and slow conversion of SO2 to SO4(2-).(ABSTRACT TRUNCATED AT 250 WORDS) PMID:7656878

  2. The semi-individual study in air pollution epidemiology: a valid design as compared to ecologic studies.

    PubMed Central

    Künzli, N; Tager, I B

    1997-01-01

    The assessment of long-term effects of air pollution in humans relies on epidemiologic studies. A widely used design consists of cross-sectional or cohort studies in which ecologic assignment of exposure, based on a fixed-site ambient monitor, is employed. Although health outcome and usually a large number of covariates are measured in individuals, these studies are often called ecological. We will introduce the term semi-individual design for these studies. We review the major properties and limitations with regard to causal inference of truly ecologic studies, in which outcome, exposure, and covariates are available on an aggregate level only. Misclassification problems and issues related to confounding and model specification in truly ecologic studies limit etiologic inference to individuals. In contrast, the semi-individual study shares its methodological and inferential properties with typical individual-level study designs. The major caveat relates to the case where too few study areas, e.g., two or three, are used, which render control of aggregate level confounding impossible. The issue of exposure misclassification is of general concern in epidemiology and not an exclusive problem of the semi-individual design. In a multicenter setting, the semi-individual study is a valuable tool to approach long-term effects of air pollution. Knowledge about the error structure of the ecologically assigned exposure allows consideration of the impact of ecologically assigned exposure on effect estimation. Semi-individual studies, i.e., individual level air pollution studies with ecologic exposure assignment, more readily permit valid inference to individuals and should not be labeled as ecologic studies. PMID:9349825

  3. A comparison of exposure metrics for traffic-related air pollutants: application to epidemiology studies in Detroit, Michigan.

    PubMed

    Batterman, Stuart; Burke, Janet; Isakov, Vlad; Lewis, Toby; Mukherjee, Bhramar; Robins, Thomas

    2014-09-01

    Vehicles are major sources of air pollutant emissions, and individuals living near large roads endure high exposures and health risks associated with traffic-related air pollutants. Air pollution epidemiology, health risk, environmental justice, and transportation planning studies would all benefit from an improved understanding of the key information and metrics needed to assess exposures, as well as the strengths and limitations of alternate exposure metrics. This study develops and evaluates several metrics for characterizing exposure to traffic-related air pollutants for the 218 residential locations of participants in the NEXUS epidemiology study conducted in Detroit (MI, USA). Exposure metrics included proximity to major roads, traffic volume, vehicle mix, traffic density, vehicle exhaust emissions density, and pollutant concentrations predicted by dispersion models. Results presented for each metric include comparisons of exposure distributions, spatial variability, intraclass correlation, concordance and discordance rates, and overall strengths and limitations. While showing some agreement, the simple categorical and proximity classifications (e.g., high diesel/low diesel traffic roads and distance from major roads) do not reflect the range and overlap of exposures seen in the other metrics. Information provided by the traffic density metric, defined as the number of kilometers traveled (VKT) per day within a 300 m buffer around each home, was reasonably consistent with the more sophisticated metrics. Dispersion modeling provided spatially- and temporally-resolved concentrations, along with apportionments that separated concentrations due to traffic emissions and other sources. While several of the exposure metrics showed broad agreement, including traffic density, emissions density and modeled concentrations, these alternatives still produced exposure classifications that differed for a substantial fraction of study participants, e.g., from 20% to 50% of

  4. A Comparison of Exposure Metrics for Traffic-Related Air Pollutants: Application to Epidemiology Studies in Detroit, Michigan

    PubMed Central

    Batterman, Stuart; Burke, Janet; Isakov, Vlad; Lewis, Toby; Mukherjee, Bhramar; Robins, Thomas

    2014-01-01

    Vehicles are major sources of air pollutant emissions, and individuals living near large roads endure high exposures and health risks associated with traffic-related air pollutants. Air pollution epidemiology, health risk, environmental justice, and transportation planning studies would all benefit from an improved understanding of the key information and metrics needed to assess exposures, as well as the strengths and limitations of alternate exposure metrics. This study develops and evaluates several metrics for characterizing exposure to traffic-related air pollutants for the 218 residential locations of participants in the NEXUS epidemiology study conducted in Detroit (MI, USA). Exposure metrics included proximity to major roads, traffic volume, vehicle mix, traffic density, vehicle exhaust emissions density, and pollutant concentrations predicted by dispersion models. Results presented for each metric include comparisons of exposure distributions, spatial variability, intraclass correlation, concordance and discordance rates, and overall strengths and limitations. While showing some agreement, the simple categorical and proximity classifications (e.g., high diesel/low diesel traffic roads and distance from major roads) do not reflect the range and overlap of exposures seen in the other metrics. Information provided by the traffic density metric, defined as the number of kilometers traveled (VKT) per day within a 300 m buffer around each home, was reasonably consistent with the more sophisticated metrics. Dispersion modeling provided spatially- and temporally-resolved concentrations, along with apportionments that separated concentrations due to traffic emissions and other sources. While several of the exposure metrics showed broad agreement, including traffic density, emissions density and modeled concentrations, these alternatives still produced exposure classifications that differed for a substantial fraction of study participants, e.g., from 20% to 50% of

  5. Impact of air pollutants from surface transport sources on human health: A modeling and epidemiological approach.

    PubMed

    Aggarwal, Preeti; Jain, Suresh

    2015-10-01

    This study adopted an integrated 'source-to-receptor' assessment paradigm in order to determine the effects of emissions from passenger transport on urban air quality and human health in the megacity, Delhi. The emission modeling was carried out for the base year 2007 and three alternate (ALT) policy scenarios along with a business as usual (BAU) scenario for the year 2021. An Activity-Structure-Emission Factor (ASF) framework was adapted for emission modeling, followed by a grid-wise air quality assessment using AERMOD and a health impact assessment using an epidemiological approach. It was observed that a 2021-ALT-III scenario resulted in a maximum concentration reduction of ~24%, ~42% and ~58% for carbon monoxide (CO), nitrogen dioxide (NO2) and particulate matter (PM), respectively, compared to a 2021-BAU scenario. Further, it results in significant reductions in respiratory and cardiovascular mortality, morbidity and Disability Adjusted Life Years (DALY) by 41% and 58% on exposure to PM2.5 and NO2 concentrations when compared to the 2021-BAU scenario, respectively. In other words, a mix of proposed policy interventions namely the full-phased introduction of the Integrated Mass Transit System, fixed bus speed, stringent vehicle emission norms and a hike in parking fees for private vehicles would help in strengthening the capability of passenger transport to cater to a growing transport demand with a minimum health burden in the Delhi region. Further, the study estimated that the transport of goods would be responsible for ~5.5% additional VKT in the 2021-BAU scenario; however, it will contribute ~49% and ~55% additional NO2 and PM2.5 concentrations, respectively, in the Delhi region. Implementation of diesel particulate filters for goods vehicles in the 2021-ALT-IV-O scenario would help in the reduction of ~87% of PM2.5 concentration, compared to the 2021-BAU scenario; translating into a gain of 1267 and 505 DALY per million people from exposure to PM2.5 and NO

  6. Air Pollution.

    ERIC Educational Resources Information Center

    Barker, K.; And Others

    Pollution of the general environment, which exposes an entire population group for an indeterminate period of time, certainly constitutes a problem in public health. Serious aid pollution episodes have resulted in increased mortality and a possible relationship between chronic exposure to a polluted atmosphere and certain diseases has been…

  7. Outdoor air pollution and asthma

    PubMed Central

    Guarnieri, Michael; Balmes, John R.

    2015-01-01

    Traffic and power generation are the main sources of urban air pollution. The idea that outdoor air pollution can cause exacerbations of pre-existing asthma is supported by an evidence base that has been accumulating for several decades, with several studies suggesting a contribution to new-onset asthma as well. In this Series paper, we discuss the effects of particulate matter (PM), gaseous pollutants (ozone, nitrogen dioxide, and sulphur dioxide), and mixed traffic-related air pollution. We focus on clinical studies, both epidemiological and experimental, published in the previous 5 years. From a mechanistic perspective, air pollutants probably cause oxidative injury to the airways, leading to inflammation, remodelling, and increased risk of sensitisation. Although several pollutants have been linked to new-onset asthma, the strength of the evidence is variable. We also discuss clinical implications, policy issues, and research gaps relevant to air pollution and asthma. PMID:24792855

  8. Performances of Different Global Positioning System Devices for Time-Location Tracking in Air Pollution Epidemiological Studies

    PubMed Central

    Wu, Jun; Jiang, Chengsheng; Liu, Zhen; Houston, Douglas; Jaimes, Guillermo; McConnell, Rob

    2010-01-01

    Background: People’s time-location patterns are important in air pollution exposure assessment because pollution levels may vary considerably by location. A growing number of studies are using global positioning systems (GPS) to track people’s time-location patterns. Many portable GPS units that archive location are commercially available at a cost that makes their use feasible for epidemiological studies. Methods: We evaluated the performance of five portable GPS data loggers and two GPS cell phones by examining positional accuracy in typical locations (indoor, outdoor, in-vehicle) and factors that influence satellite reception (building material, building type), acquisition time (cold and warm start), battery life, and adequacy of memory for data storage. We examined stationary locations (eg, indoor, outdoor) and mobile environments (eg, walking, traveling by vehicle or bus) and compared GPS locations to highly-resolved US Geological Survey (USGS) and Digital Orthophoto Quarter Quadrangle (DOQQ) maps. Results: The battery life of our tested instruments ranged from <9 hours to 48 hours. The acquisition of location time after startup ranged from a few seconds to >20 minutes and varied significantly by building structure type and by cold or warm start. No GPS device was found to have consistently superior performance with regard to spatial accuracy and signal loss. At fixed outdoor locations, 65%–95% of GPS points fell within 20-m of the corresponding DOQQ locations for all the devices. At fixed indoor locations, 50%–80% of GPS points fell within 20-m of the corresponding DOQQ locations for all the devices except one. Most of the GPS devices performed well during commuting on a freeway, with >80% of points within 10-m of the DOQQ route, but the performance was significantly impacted by surrounding structures on surface streets in highly urbanized areas. Conclusions: All the tested GPS devices had limitations, but we identified several devices which showed

  9. Application of alternative spatiotemporal metrics of ambient air pollution exposure in a time-series epidemiological study in Atlanta

    EPA Science Inventory

    Exposure error in studies of ambient air pollution and health that use city-wide measures of exposure may be substantial for pollutants that exhibit spatiotemporal variability. Alternative spatiotemporal metrics of exposure for traffic-related and regional pollutants were applied...

  10. Indoor Air Pollution

    MedlinePlus

    We usually think of air pollution as being outdoors, but the air in your house or office could also be polluted. Sources of indoor pollution include Mold and pollen Tobacco smoke Household products ...

  11. A Review of the Epidemiological Methods Used to Investigate the Health Impacts of Air Pollution around Major Industrial Areas

    PubMed Central

    Pascal, Laurence; Bidondo, Marie-Laure; Cochet, Amandine; Sarter, Hélène; Stempfelet, Morgane; Wagner, Vérène

    2013-01-01

    We performed a literature review to investigate how epidemiological studies have been used to assess the health consequences of living in the vicinity of industries. 77 papers on the chronic effects of air pollution around major industrial areas were reviewed. Major health themes were cancers (27 studies), morbidity (25 studies), mortality (7 studies), and birth outcome (7 studies). Only 3 studies investigated mental health. While studies were available from many different countries, a majority of papers came from the United Kingdom, Italy, and Spain. Several studies were motivated by concerns from the population or by previous observations of an overincidence of cases. Geographical ecological designs were largely used for studying cancer and mortality, including statistical designs to quantify a relationship between health indicators and exposure. Morbidity was frequently investigated through cross-sectional surveys on the respiratory health of children. Few multicenter studies were performed. In a majority of papers, exposed areas were defined based on the distance to the industry and were located from <2 km to >20 km from the plants. Improving the exposure assessment would be an asset to future studies. Criteria to include industries in multicenter studies should be defined. PMID:23818910

  12. ENHANCED AIR POLLUTION EPIDEMIOLOGY USING A SOURCE-ORIENTED CHEMICAL TRANSPORT MODEL

    EPA Science Inventory

    Air quality model predictions describing source-oriented PM component concentrations in multiple size cuts will provide new inputs to examine the effects of acute and chronic PM exposure on mortality and morbidity. Associations between adverse health effects and PM sources/com...

  13. Lung cancer and air pollution.

    PubMed Central

    Cohen, A J; Pope, C A

    1995-01-01

    Epidemiologic studies over the last 40 years suggest rather consistently that general ambient air pollution, chiefly due to the incomplete combustion of fossil fuels, may be responsible for increased rates of lung cancer. This evidence derives from studies of lung cancer trends, studies of occupational groups, comparisons of urban and rural populations, and case-control and cohort studies using diverse exposure metrics. Recent prospective cohort studies observed 30 to 50% increases in lung cancer rates associated with exposure to respirable particles. While these data reflect the effects of exposures in past decades, and despite some progress in reducing air pollution, large numbers of people in the United States continue to be exposed to pollutant mixtures containing known or suspected carcinogens. It is not known how many people in the United States are exposed to levels of fine respirable particles that have been associated with lung cancer in recent epidemiologic studies. These observations suggest that the most widely cited estimates of the proportional contribution of air pollution to lung cancer occurrence in the United States based largely on the results of animal studies, may be too low. It is important that better epidemiologic research be conducted to allow improved estimates of lung cancer risk from air pollution among the general population. The development and application of new epidemiologic methods, particularly the improved characterization of population-wide exposure to mixtures of air pollutants and the improved design of ecologic studies, could improve our ability to measure accurately the magnitude of excess cancer associated with air pollution. PMID:8741787

  14. Application of alternative spatiotemporal metrics of ambient air pollution exposure in a time-series epidemiological study in Atlanta.

    PubMed

    Sarnat, Stefanie Ebelt; Sarnat, Jeremy A; Mulholland, James; Isakov, Vlad; Özkaynak, Halûk; Chang, Howard H; Klein, Mitchel; Tolbert, Paige E

    2013-01-01

    Exposure error in studies of ambient air pollution and health that use city-wide measures of exposure may be substantial for pollutants that exhibit spatiotemporal variability. Alternative spatiotemporal metrics of exposure for traffic-related and regional pollutants were applied in a time-series study of ambient air pollution and cardiorespiratory emergency department visits in Atlanta, GA, USA. Exposure metrics included daily central site monitoring for particles and gases; daily spatially refined ambient concentrations obtained from regional background monitors, local-scale dispersion, and hybrid air quality models; and spatially refined ambient exposures from population exposure models. Health risk estimates from Poisson models using the different exposure metrics were compared. We observed stronger associations, particularly for traffic-related pollutants, when using spatially refined ambient concentrations compared with a conventional central site exposure assignment approach. For some relationships, estimates of spatially refined ambient population exposures showed slightly stronger associations than corresponding spatially refined ambient concentrations. Using spatially refined pollutant metrics, we identified socioeconomic disparities in concentration-response functions that were not observed when using central site data. In some cases, spatially refined pollutant metrics identified associations with health that were not observed using measurements from the central site. Complexity and challenges in incorporating modeled pollutant estimates in time-series studies are discussed. PMID:23963512

  15. Indoor Air Pollution

    MedlinePlus

    We usually think of air pollution as being outdoors, but the air in your house or office could also be polluted. Sources of indoor pollution ... is known as sick building syndrome. Usually indoor air quality problems only cause discomfort. Most people feel ...

  16. Air Pollution Training Programs.

    ERIC Educational Resources Information Center

    Public Health Service (DHEW), Rockville, MD.

    This catalog lists the universities, both supported and not supported by the Division of Air Pollution, which offer graduate programs in the field of air pollution. The catalog briefly describes the programs and their entrance requirements, the requirements, qualifications and terms of special fellowships offered by the Division of Air Pollution.…

  17. Air pollution and society

    NASA Astrophysics Data System (ADS)

    Brimblecombe, P.

    2010-12-01

    Air pollution is as much a product of our society as it is one of chemistry and meteorology. Social variables such as gender, age, health status and poverty are often linked with our exposure to air pollutants. Pollution can also affect our behaviour, while regulations to improve the environment can often challenge of freedom.

  18. Discriminatory Air Pollution

    ERIC Educational Resources Information Center

    McCaull, Julian

    1976-01-01

    Described are the patterns of air pollution in certain large urban areas. Persons in poverty, in occupations below the management or professional level, in low-rent districts, and in black population are most heavily exposed to air pollution. Pollution paradoxically is largely produced by high energy consuming middle-and upper-class households.…

  19. Air Pollution, Teachers' Edition.

    ERIC Educational Resources Information Center

    Lavaroni, Charles W.; O'Donnell, Patrick A.

    One of three in a series about pollution, this teacher's guide for a unit on air pollution is designed for use in junior high school grades. It offers suggestions for extending the information and activities contained in the textual material for students. Chapter 1 discusses the problem of air pollution and involves students in processes of…

  20. Air pollution and respiratory viral infection

    EPA Science Inventory

    Despite current regulations, which limit the levels of certain air pollutants, there are still a number of adverse health effects that result from exposure to these agents. Numerous epidemiological studies have noted an association between the levels of air pollution and hospital...

  1. [Epidemiological studies of air pollution and health effects in areas near roadways with heavy traffic in Tokyo].

    PubMed

    Ono, M; Murakami, M; Nitta, H; Nakai, S; Maeda, K

    1990-05-01

    Recent concern regarding health effects of air pollution in Japan has concentrated mainly on traffic-induced air pollution and its health effects in large cities. In Japan, where many people in large cities have been living near major roadways, the increase of automobile exhaust due to heavy traffic congestion will predictably cause a greater impact on people living near major roadways. We surveyed the characterization of residential suspended particulate matter (SPM) and nitrogen dioxide (NO2) concentrations along the major roadways in Tokyo, along with a health survey on the respiratory conditions of residents living in the same area, to examine the relationships between indoor pollutant levels, prevalence of respiratory symptoms and distance from roadways. The environmental monitoring was conducted in five phases. Using a newly developed SPM sampler and NO2 filter badge, continuous 4 day (96 hours) measurements were conducted in two hundred residential homes for four weeks. NO2 was measured in the living room, kitchen and outside of each home, while SPM was monitored in the living room. Health information was collected in October 1987 using ATS-DLD self-administered questionnaires. Of the 1,093 homes investigated, responses from 805 homes were received. The following results were obtained. SPM and NO2 concentrations showed large variations. Indoor pollution levels mostly depended on indoor sources, i.e. cigarette smoking and unventilated space heaters, and the effects of those indoor sources were influenced by the building structure with respect to air tightness. An association between increase in pollutant levels and the distance from the roadway was observed. However its effect is small compared to indoor source effects. The prevalence rate of respiratory symptoms was higher in those areas nearest roadways with heavy traffic both in children and adults. These results suggest the presence of a relationship between automobile exhaust and health effects. PMID

  2. Epidemiologic investigation to identify chronic health effects of ambient air pollutants in Southern California. Phase 2. Final report

    SciTech Connect

    Peters, J.M.

    1997-09-01

    The Phase II cross-sectional study was conducted to provide early information on the possible chronic effects of air pollution in Southern California children and to determine, if effects are found, which pollutant (or pollutants) is responsible. Annual questionnaires were completed on these children which covered health history (including history of wheezing, asthma, bronchitis, pneumonia and other respiratory conditions), residential history, housing characteristics (such as heating and air conditioning practices), and history of exposure to other possibly harmful agents, such as tobacco smoke (both active and passive smoking). In addition, the usual physical and outdoor/indoor activity of each subject was ascertained. The lung function of each subject was assessed annually to determine ventilatory capacity. School absenses were recorded to determine frequency and severity of respiratory illnesses. After the development and deployment of the instrumentation, monitoring for air pollutants was conducted for the twelve communities, the schools and a sample of the subject`s residences. Ozone, PM{sub 10}, PM{sub 2.5}, NO{sub 2}, and acid vapor concentrations were determined at the community level, and indoor ozone concentrations were measured at schools. A sample of homes was measured for indoor ozone, PM{sub 10}, PM{sub 2.5}, acid and formaldehyde. The information from the questionnaire on residential history allowed for the construction of an estimated life-time exposure level for the different pollutants based on existing data. The information collected at schools and homes allowed for adjustments for exposures based on whether the subjects were indoors or outdoors.

  3. Controlling Indoor Air Pollution.

    ERIC Educational Resources Information Center

    Nero, Anthony V, Jr.

    1988-01-01

    Discusses the health risks posed by indoor air pollutants, such as airborne combustion products, toxic chemicals, and radioactivity. Questions as to how indoor air might be regulated. Calls for new approaches to environmental protection. (TW)

  4. Health Effects of Air Pollution

    MedlinePlus

    ... Health effects of air pollution Health effects of air pollution Breathing air that is not clean can hurt ... important to know about the health effects that air pollution can have on you and others. Once you ...

  5. IMMUNOTOXICITY OF AIR POLLUTANTS

    EPA Science Inventory

    The most common ubiquitous air pollutants, as well as some point source (e.g. metals) air pollutants, decrease the function of pulmonary host defense mechanisms against infection. Most of this knowledge is based on animal studies and involves cellular antibacterial defenses such ...

  6. Air Pollution and Industry.

    ERIC Educational Resources Information Center

    Ross, R. D., Ed.

    This book is an authoritative reference and practical guide designed to help the plant engineer identify and solve industrial air pollution problems in order to be able to meet current air pollution regulations. Prepared under the editorial supervision of an experienced chemical engineer, with each chapter contributed by an expert in his field,…

  7. A review of low-level air pollution and adverse effects on human health: implications for epidemiological studies and public policy

    PubMed Central

    Olmo, Neide Regina Simões; do Nascimento Saldiva, Paulo Hilário; Braga, Alfésio Luís Ferreira; Lin, Chin An; de Paula Santos, Ubiratan; Pereira, Luiz Alberto Amador

    2011-01-01

    The aim of this study was to review original scientific articles describing the relationship between atmospheric pollution and damage to human health. We also aimed to determine which of these studies mentioned public policy issues. Original articles relating to atmospheric pollution and human health published between 1995 and 2009 were retrieved from the PubMed database and analyzed. This study included only articles dealing with atmospheric pollutants resulting primarily from vehicle emissions. Three researchers were involved in the final selection of the studies, and the chosen articles were approved by at least two of the three researchers. Of the 84 non-Brazilian studies analyzed, 80 showed an association between atmospheric pollution and adverse effects on human health. Moreover, 66 showed evidence of adverse effects on human health, even at levels below the permitted emission standards. Three studies mentioned public policies aimed at changing emission standards. Similarly, the 29 selected Brazilian studies reported adverse associations with human health, and 27 showed evidence of adverse effects even at levels below the legally permitted emission standards. Of these studies, 16 mentioned public policies aimed at changing emission standards. Based on the Brazilian and non-Brazilian scientific studies that have been conducted, it can be concluded that, even under conditions that are compliant with Brazilian air quality standards, the concentration of atmospheric pollutants in Brazil can negatively affect human health. However, as little discussion of this topic has been generated, this finding demonstrates the need to incorporate epidemiological evidence into decisions regarding legal regulations and to discuss the public policy implications in epidemiological studies. PMID:21655765

  8. Investigating Air Pollution

    ERIC Educational Resources Information Center

    Carter, Edward J.

    1977-01-01

    Describes an experiment using live plants and cigarette smoke to demonstrate the effects of air pollution on a living organism. Procedures include growth of the test plants in glass bottles, and construction and operation of smoking machine. (CS)

  9. AIR POLLUTION CONTROL TECHNOLOGIES

    EPA Science Inventory

    This is a chapter for John Wiley & Son's Mechanical Engineers' Handbook, and covers issues involving air pollution control. Various technologies for controlling sulfur oxides is considered including fuel desulfurization. It also considers control of nitrogen oxides including post...

  10. Air pollution from aircraft

    NASA Technical Reports Server (NTRS)

    Heywood, J. B.; Fay, J. A.; Chigier, N. A.

    1979-01-01

    A series of fundamental problems related to jet engine air pollution and combustion were examined. These include soot formation and oxidation, nitric oxide and carbon monoxide emissions mechanisms, pollutant dispension, flow and combustion characteristics of the NASA swirl can combustor, fuel atomization and fuel-air mixing processes, fuel spray drop velocity and size measurement, ignition and blowout. A summary of this work, and a bibliography of 41 theses and publications which describe this work, with abstracts, is included.

  11. Air Pollution Surveillance Systems

    ERIC Educational Resources Information Center

    Morgan, George B.; And Others

    1970-01-01

    Describes atmospheric data monitoring as part of total airpollution control effort. Summarizes types of gaseous, liquid and solid pollutants and their sources; contrast between urban and rural environmental air quality; instrumentation to identify pollutants; and anticipated new non-wet chemical physical and physiochemical techniques tor cetection…

  12. Air pollution and cardiovascular disease.

    PubMed

    Franklin, Barry A; Brook, Robert; Arden Pope, C

    2015-05-01

    An escalating body of epidemiologic and clinical research provides compelling evidence that exposure to fine particulate matter air pollution contributes to the development of cardiovascular disease and the triggering of acute cardiac events. There are 3 potential mediating pathways that have been implicated, including "systemic spillover," autonomic imbalance, and circulating particulate matter constituents. Further support that the increased morbidity and mortality attributed to air pollution comes from studies demonstrating the adverse cardiovascular effects of even brief periods of exposure to secondhand smoke. Accordingly, persons with known or suspected cardiovascular disease, the elderly, diabetic patients, pregnant women, and those with pulmonary disease should be counseled to limit leisure-time outdoor activities when air pollution is high. Recognizing the insidious and pervasive nature of air pollution, and the associated odds ratios and population attributable fractions for this widely underappreciated chemical trigger of acute cardiovascular events, may serve to maximize the potential for cardiovascular risk reduction by addressing at least a portion of the 10%-25% incidence of coronary disease that is unexplained by traditional risk factors. PMID:25882781

  13. Air Pollution Primer.

    ERIC Educational Resources Information Center

    National Tuberculosis and Respiratory Disease Association, New York, NY.

    As the dangers of polluted air to the health and welfare of all individuals became increasingly evident and as the complexity of the causes made responsibility for solutions even more difficult to fix, the National Tuberculosis and Respiratory Disease Association felt obligated to give greater emphasis to its clean air program. To this end they…

  14. Particulate Air Pollution: The Particulars

    ERIC Educational Resources Information Center

    Murphy, James E.

    1973-01-01

    Describes some of the causes and consequences of particulate air pollution. Outlines the experimental procedures for measuring the amount of particulate materials that settles from the air and for observing the nature of particulate air pollution. (JR)

  15. Wastewater-based epidemiological evaluation of the effect of air pollution on short-acting beta-agonist consumption for acute asthma treatment.

    PubMed

    Fattore, Elena; Davoli, Enrico; Castiglioni, Sara; Bosetti, Cristina; Re Depaolini, Andrea; Marzona, Irene; Zuccato, Ettore; Fanelli, Roberto

    2016-10-01

    Asthma, one of the most common chronic diseases in the world and a leading cause of hospitalization among children, has been associated with outdoor air pollution. We applied the wastewater-based epidemiology (WBE) approach to study the association between the use of salbutamol, a short-acting beta-agonist used to treat acute bronchospasm, and air pollution in the population of Milan, Italy. Composite 24-h samples of untreated wastewater were collected daily and analyzed for human metabolic residues of salbutamol by liquid chromatography tandem mass spectrometry. Corresponding daily outdoor concentrations of particular matter up to 10µm (PM10) and 2.5µm (PM2.5) in aerodynamic diameter, nitrogen dioxide, ozone, sulfur dioxide, and benzene were collected from the public air monitoring network. Associations at different lag times (0-10 days) were assessed by a log-linear Poisson regression model. We found significant direct associations between defined daily doses (DDD) of salbutamol and mean daily concentrations of PM10 and PM2.5 up to nine days of lag time. The highest rate ratio, and 95% confidence interval (CI), of DDD of salbutamol was 1.06 (95% CI: 1.02-1.10) and 1.07 (95% CI: 1.02-1.12) at seven days of lag time and for an increase of 10 μg/m(3) of PM10 and PM2.5, respectively. Reducing the mean daily PM10 concentration in Milan from 50 to 30μg/m(3) means that 852 (95% CI: 483-1504) daily doses of salbutamol per day would not be used. These results confirm the association between asthma and outdoor PM10 and PM2.5 and prove the potential of the WBE approach to quantitatively estimate the relation between environmental exposures and diseases. PMID:27281687

  16. Basic mechanisms for adverse cardiovascular events associated with air pollution

    PubMed Central

    Chin, Michael T.

    2015-01-01

    Air pollution is a significant cause of cardiovascular morbidity and mortality worldwide. Although the epidemiologic association between air pollution exposures and exacerbation of cardiovascular disease is well established, the mechanisms by which these exposures promote cardiovascular disease are incompletely understood. In this review I will give an overview of the components of air pollution, an overview of the cardiovascular effects of air pollution exposure and a review of the basic mechanisms that are activated by exposure to promote cardiovascular disease. PMID:25552258

  17. Pupils' Understanding of Air Pollution

    ERIC Educational Resources Information Center

    Dimitriou, Anastasia; Christidou, Vasilia

    2007-01-01

    This paper reports on a study of pupils' knowledge and understanding of atmospheric pollution. Specifically, the study is aimed at identifying: 1) the extent to which pupils conceptualise the term "air pollution" in a scientifically appropriate way; 2) pupils' knowledge of air pollution sources and air pollutants; and 3) pupils' knowledge of air…

  18. The Particulate Air Pollution Controversy

    PubMed Central

    Phalen, Robert F.

    2004-01-01

    Scientists, regulators, legislators, and segments of industry and the lay public are attempting to understand and respond to epidemiology findings of associations between measures of modern particulate air pollutants (PM) and adverse health outcomes in urban dwellers. The associations have been interpreted to imply that tens of thousands of Americans are killed annually by small daily increments in PM. These epidemiology studies and their interpretations have been challenged, although it is accepted that high concentrations of air pollutants have claimed many lives in the past. Although reproducible and statistically significant, the relative risks associated with modern PM are very small and confounded by many factors. Neither toxicology studies nor human clinical investigations have identified the components and/or characteristics of PM that might be causing the health-effect associations. Currently, a massive worldwide research effort is under way in an attempt to identify whom might be harmed and by what substances and mechanisms. Finding the answers is important, because control measures have the potential not only to be costly but also to limit the availability of goods and services that are important to public health. PMID:19330148

  19. Testing for Air Pollution.

    ERIC Educational Resources Information Center

    Dunbar, Artice

    Three experiments are presented in this Science Study Aid to provide the teacher with some fundamental air pollution activities. The first experiment involved particulates, the second deals with microorganisms, and the third looks at gases in the atmosphere. Each activity outlines introductory information, objectives, materials required, procedure…

  20. AIR POLLUTION AND HUMMINGBIRDS

    EPA Science Inventory

    A multidisciplinary team of EPA-RTP ORD pulmonary toxicologists, engineers, ecologists, and statisticians have designed a study of how ground-level ozone and other air pollutants may influence feeding activity of the ruby-throated hummingbird (Archilochus colubris). Be...

  1. Human health effects of air pollution.

    PubMed Central

    Folinsbee, L J

    1993-01-01

    Over the past three or four decades, there have been important advances in the understanding of the actions, exposure-response characteristics, and mechanisms of action of many common air pollutants. A multidisciplinary approach using epidemiology, animal toxicology, and controlled human exposure studies has contributed to the database. This review will emphasize studies of humans but will also draw on findings from the other disciplines. Air pollutants have been shown to cause responses ranging from reversible changes in respiratory symptoms and lung function, changes in airway reactivity and inflammation, structural remodeling of pulmonary airways, and impairment of pulmonary host defenses, to increased respiratory morbidity and mortality. Quantitative and qualitative understanding of the effects of a small group of air pollutants has advanced considerably, but the understanding is by no means complete, and the breadth of effects of all air pollutants is only partially understood. PMID:8354181

  2. Outdoor air pollution and lung cancer.

    PubMed Central

    Cohen, A J

    2000-01-01

    In the 1950s evidence of an ongoing epidemic of lung cancer in the United States and Western Europe led researchers to examine the role of outdoor air pollution, which was considered by some to be a likely cause. Although epidemiologic research quickly identified the central role of cigarette smoking in this epidemic, and despite progress in reducing outdoor air pollution in Western industrialized countries, concerns that ambient air pollution is causing lung cancer have persisted to the present day. This concern is based on the fact that known carcinogens continue to be released into outdoor air from industrial sources, power plants, and motor vehicles, and on a body of epidemiologic research that provides some evidence for an association between outdoor air pollution and lung cancer. This article reviews the epidemiologic evidence for this association and discusses the limitations of current studies for estimating the lung cancer risk in the general population. It also identifies research needs and suggests possible approaches to addressing outstanding questions. PMID:10931793

  3. Molecular epidemiology of severe ambient air pollution on women and the developing fetus. Final report, September 15, 1993--September 14, 1996

    SciTech Connect

    Perera, F.P.

    1997-11-01

    This research goal was validation of a number of biomarkers in two groups of Polish women and their newborn infants: 70 mother/child pairs from Krakow, a city with elevated air pollution and 90 pairs from Limanowa, a less polluted area.

  4. Geographical information system and environmental epidemiology: a cross-sectional spatial analysis of the effects of traffic-related air pollution on population respiratory health

    PubMed Central

    2011-01-01

    Background Traffic-related air pollution is a potential risk factor for human respiratory health. A Geographical Information System (GIS) approach was used to examine whether distance from a main road (the Tosco-Romagnola road) affected respiratory health status. Methods We used data collected during an epidemiological survey performed in the Pisa-Cascina area (central Italy) in the period 1991-93. A total of 2841 subjects participated in the survey and filled out a standardized questionnaire on health status, socio-demographic information, and personal habits. A variable proportion of subjects performed lung function and allergy tests. Highly exposed subjects were defined as those living within 100 m of the main road, moderately exposed as those living between 100 and 250 m from the road, and unexposed as those living between 250 and 800 m from the road. Statistical analyses were conducted to compare the risks for respiratory symptoms and diseases between exposed and unexposed. All analyses were stratified by gender. Results The study comprised 2062 subjects: mean age was 45.9 years for men and 48.9 years for women. Compared to subjects living between 250 m and 800 m from the main road, subjects living within 100 m of the main road had increased adjusted risks for persistent wheeze (OR = 1.76, 95% CI = 1.08-2.87), COPD diagnosis (OR = 1.80, 95% CI = 1.03-3.08), and reduced FEV1/FVC ratio (OR = 2.07, 95% CI = 1.11-3.87) among males, and for dyspnea (OR = 1.61, 95% CI = 1.13-2.27), positivity to skin prick test (OR = 1.83, 95% CI = 1.11-3.00), asthma diagnosis (OR = 1.68, 95% CI = 0.97-2.88) and attacks of shortness of breath with wheeze (OR = 1.67, 95% CI = 0.98-2.84) among females. Conclusion This study points out the potential effects of traffic-related air pollution on respiratory health status, including lung function impairment. It also highlights the added value of GIS in environmental health research. PMID:21362158

  5. Air pollution source identification

    NASA Technical Reports Server (NTRS)

    Fordyce, J. S.

    1975-01-01

    Techniques for air pollution source identification are reviewed, and some results obtained with them are evaluated. Described techniques include remote sensing from satellites and aircraft, on-site monitoring, and the use of injected tracers and pollutants themselves as tracers. The use of a large number of trace elements in ambient airborne particulate matter as a practical means of identifying sources is discussed in detail. Sampling and analysis techniques are described, and it is shown that elemental constituents can be related to specific source types such as those found in the earth's crust and those associated with specific industries. Source identification sytems are noted which utilize charged particle X-ray fluorescence analysis of original field data.

  6. Remote air pollution measurement

    NASA Technical Reports Server (NTRS)

    Byer, R. L.

    1975-01-01

    This paper presents a discussion and comparison of the Raman method, the resonance and fluorescence backscatter method, long path absorption methods and the differential absorption method for remote air pollution measurement. A comparison of the above remote detection methods shows that the absorption methods offer the most sensitivity at the least required transmitted energy. Topographical absorption provides the advantage of a single ended measurement, and differential absorption offers the additional advantage of a fully depth resolved absorption measurement. Recent experimental results confirming the range and sensitivity of the methods are presented.

  7. Air Pollution Control, Part I.

    ERIC Educational Resources Information Center

    Strauss, Werner, Ed.

    Authoritative reviews in seven areas of current importance in air pollution control are supplied in this volume, the first of a two-part set. Titles contained in this book are: "Dispersion of Pollutants Emitted into the Atmosphere,""The Formation and Control of Oxides of Nitrogen in Air Pollution,""The Control of Sulfur Emissions from Combustion…

  8. The Federal Air Pollution Program.

    ERIC Educational Resources Information Center

    National Air Pollution Control Administration (DHEW), Washington, DC.

    Described is the Federal air pollution program as it was in 1967. The booklet is divided into these major topics: History of the Federal Program; Research; Assistance to State and Local Governments; Abatement and Prevention of Air Pollution; Control of Motor Vehicle Pollution; Information and Education; and Conclusion. Federal legislation has…

  9. In Search of Air Pollution

    ERIC Educational Resources Information Center

    Beckendorf, Kirk

    2006-01-01

    Air pollution is no longer just a local issue; it is a global problem. The atmosphere is a very dynamic system. Pollution not only changes in chemical composition after it is emitted, but also is transported on local and global air systems hundreds and even thousands of miles away. Some of the pollutants that are major health concerns are not even…

  10. MODELING POPULATION EXPOSURES TO OUTDOOR SOURCES OF HAZARDOUS AIR POLLUTANTS

    EPA Science Inventory

    Accurate assessment of human exposures is an important part of environmental health effects research. However, most air pollution epidemiology studies rely upon imperfect surrogates of personal exposures, such as information based on available central-site outdoor concentration ...

  11. Air pollution from aircraft

    NASA Technical Reports Server (NTRS)

    Heywood, J. B.; Fay, J. A.; Chigier, N. A.

    1979-01-01

    Forty-one annotated abstracts of reports generated at MIT and the University of Sheffield are presented along with summaries of the technical projects undertaken. Work completed includes: (1) an analysis of the soot formation and oxidation rates in gas turbine combustors, (2) modelling the nitric oxide formation process in gas turbine combustors, (3) a study of the mechanisms causing high carbon monoxide emissions from gas turbines at low power, (4) an analysis of the dispersion of pollutants from aircraft both around large airports and from the wakes of subsonic and supersonic aircraft, (5) a study of the combustion and flow characteristics of the swirl can modular combustor and the development and verification of NO sub x and CO emissions models, (6) an analysis of the influence of fuel atomizer characteristics on the fuel-air mixing process in liquid fuel spray flames, and (7) the development of models which predict the stability limits of fully and partially premixed fuel-air mixtures.

  12. Ambient particulate air pollution and ectopy--the environmental epidemiology of arrhythmogenesis in Women's Health Initiative Study, 1999-2004.

    PubMed

    Liao, Duanping; Whitsel, Eric A; Duan, Yinkang; Lin, Hung-Mo; Quibrera, P Miguel; Smith, Richard; Peuquet, Donna J; Prineas, Ronald J; Zhang, Zhu-Ming; Anderson, Garnet

    2009-01-01

    The relationships between ambient PM(2.5) and PM(10) and arrhythmia and the effect modification by cigarette smoking were investigated. Data from U.S. Environmental Protection Agency (EPA) air quality monitors and an established national-scale, log-normal kriging method were used to spatially estimate daily mean concentrations of PM at addresses of 57,422 individuals from 59 examination sites in 24 U.S. states in 1999-2004. The acute and subacute exposures were estimated as mean, geocoded address-specific PM concentrations on the day of, 0-2 d before, and averaged over 30 d before the electrocardiogram (ECG) (Lag(0); Lag(1); Lag(2); Lag(1-30)). At the time of standard 12-lead resting ECG, the mean age (SD) of participants was 67.5 (6.9) yr (84% non-Hispanic White; 6% current smoker; 15% with coronary heart disease; 5% with ectopy). After the identification of significant effect modifiers, two-stage random-effects models were used to calculate center-pooled odds ratios and 95% confidence intervals (OR, 95% CI) of arrhythmia per 10 mug/m(3) increase in PM concentrations. Among current smokers, Lag(0) and Lag(1) PM concentrations were significantly associated ventricular ectopy (VE)-the OR (95% CI) for VE among current smokers was 2 (1.32-3.3) and 1.32 (1.07-1.65) at Lag(1) PM(2.5) and PM(10), respectively. The interactions between current smoking and acute exposures (Lag(0); Lag(1); Lag(2)) were significant in relationship to VE. Acute exposures were not significantly associated with supraventricular ectopy (SVE), or with VE among nonsmokers. Subacute (Lag(1-30)) exposures were not significantly associated with arrhythmia. Acute PM(2.5) and PM(10) exposure is directly associated with the odds of VE among smokers, suggesting that they are more vulnerable to the arrhythmogenic effects of PM. PMID:18979352

  13. Air Pollution, Causes and Cures.

    ERIC Educational Resources Information Center

    Manufacturing Chemists Association, Washington, DC.

    This commentary on sources of air pollution and air purification treatments is accompanied by graphic illustrations. Sources of carbon monoxide, sulfur oxides, nitrogen oxides, and hydrocarbons found in the air are discussed. Methods of removing these pollutants at their source are presented with cut-away diagrams of the facilities and technical…

  14. Air Pollution and Infant Mortality in Mexico City

    EPA Science Inventory

    Historic air pollution episodes of the 1950s led to acute increases in infant mortality, and some recent epidemiologic studies suggest that infant or child mortality may still result from air pollution at current levels. To investigate the evidence for such an association, we con...

  15. Composition of air pollution particles modifies oxidative stress in cells, tissues, and living systems

    EPA Science Inventory

    Epidemiological studies demonstrate an association between increased levels of ambient air pollution particles and human morbidity and mortality. Production of oxidants, either directly by the air pollution particles or by the host response to the particles, appears to be fundame...

  16. Associations between criteria air pollutants and asthma

    SciTech Connect

    Koren, H.S.

    1995-09-01

    The evidence that asthma is increasing in prevalence is becoming increasingly compelling. This trend has been demonstrated in the United States, the United Kingdom, New Zealand, Australia, and several other Western countries. In the US, the increase is largest in the group under 18 years of age. There is mounting evidence that certain environmental air pollutants are involved in exacerbating asthma. This is based primarily on epidemiologic studies and more recent clinical studies. The U.S. Clean Air Act of 1970 provides special consideration to the class of outdoor air pollutants referred to as criteria pollutants, including O{sub 3}, sulfur dioxide (SO{sub 2}), particulate matter (PM), NO{sub x}, CO, and Pb. Standards for these pollutants are set by the US EPA with particular concern for populations at risk. Current evidence suggests that asthmatics are more sensitive to the effects of O{sub 3}, SO{sub 2} PM, and NO{sub 2}, and are therefore at risk. High SO{sub 2} and particulate concentrations have been associated with short-term increases in morbidity and mortality in the general population during dramatic air pollution episodes in the past. Controlled exposure studies have clearly shown that asthmatics are sensitive to low levels of SO{sub 2}. Exercising asthmatics exposed to SO{sub 2} develop bronchoconstriction within minutes, even at levels of 0.25 ppm. Responses are modified by air temperature, humidity, and exercise level. Recent epidemiologic studies have suggested that exposure to Pm is strongly associated with morbidity and mortality in the general population and that hospital admissions for bronchitis and asthma were associated with PM{sub 10} levels. In controlled clinical studies, asthmatics appear to be no more reactive to aerosols than healthy subjects. Consequently, it is difficult to attribute the increased mortality observed in epidemiologic studies to specific effects demonstrated in controlled human studies. 106 refs., 1 fig., 1 tab.

  17. Air Pollution and Human Health

    ERIC Educational Resources Information Center

    Lave, Lester B.; Seskin, Eugene P.

    1970-01-01

    Reviews studies statistically relating air pollution to mortality and morbidity rates for respiratory, and cardiovascular diseases, cancer and infant mortality. Some data recalculated. Estimates 50 percent air pollution reduction will save 4.5 percent (2080 million dollars per year) of all economic loss (hospitalization, income loss) associated…

  18. PLANT RESPONSE TO AIR POLLUTION

    EPA Science Inventory

    Air pollutants have a negative impact on plant growth, primarily through interfering with resource accumulation. ince leaves are in close contact with the atmosphere, many air pollutants, such as O3 and NOx, affect the metabolic function of the leaves and interfere with net carbo...

  19. Children, Pediatricians, and Polluted Air.

    ERIC Educational Resources Information Center

    Kane, Dorothy Noyes

    Explored are children's vulnerability and the pediatrician's role in relation to the problems posed by air pollution. Research is noted to have included a search of biomedical literature over the past 10 years; attendance at medical meetings; conferences with air pollution researchers, environmental protection administrators, and specialists in…

  20. ACRYLONITRILE PLANT AIR POLLUTION CONTROL

    EPA Science Inventory

    Based on available literature, the report identifies and ranks (in terms of efficiency, cost, and energy requirements) air pollution control technologies for each of four major air pollutant emission sources in acrylonitrile plants. The sources are: (1) absorber vent gas streams,...

  1. Intercontinental Transport of Air Pollution

    NASA Technical Reports Server (NTRS)

    Rogers, David; Whung, Pai-Yei; Einaudi, Franco (Technical Monitor)

    2001-01-01

    The development of the global economy goes beyond raising our standards of living. We are in an ear of increasing environmental as well as economic interdependence. Long-range transport of anthropogenic atmospheric pollutants such as ozone, ozone precursors, airborne particles, heavy metals (such as mercury) and persistent organic pollutants are the four major types of pollution that are transported over intercontinental distances and have global environmental effects. The talk includes: 1) an overview of the international agreements related to intercontinental transport of air pollutants, 2) information needed for decision making, 3) overview of the past research on intercontinental transport of air pollutants - a North American's perspective, and 4) future research needs.

  2. Allergic diseases and air pollution

    PubMed Central

    Lee, Suh-Young; Chang, Yoon-Seok

    2013-01-01

    The prevalence of allergic diseases has been increasing rapidly, especially in developing countries. Various adverse health outcomes such as allergic disease can be attributed to rapidly increasing air pollution levels. Rapid urbanization and increased energy consumption worldwide have exposed the human body to not only increased quantities of ambient air pollution, but also a greater variety of pollutants. Many studies clearly demonstrate that air pollutants potently trigger asthma exacerbation. Evidence that transportation-related pollutants contribute to the development of allergies is also emerging. Moreover, exposure to particulate matter, ozone, and nitrogen dioxide contributes to the increased susceptibility to respiratory infections. This article focuses on the current understanding of the detrimental effects of air pollutants on allergic disease including exacerbation to the development of asthma, allergic rhinitis, and eczema as well as epigenetic regulation. PMID:23956961

  3. Health, wealth, and air pollution: advancing theory and methods.

    PubMed Central

    O'Neill, Marie S; Jerrett, Michael; Kawachi, Ichiro; Levy, Jonathan I; Cohen, Aaron J; Gouveia, Nelson; Wilkinson, Paul; Fletcher, Tony; Cifuentes, Luis; Schwartz, Joel

    2003-01-01

    The effects of both ambient air pollution and socioeconomic position (SEP) on health are well documented. A limited number of recent studies suggest that SEP may itself play a role in the epidemiology of disease and death associated with exposure to air pollution. Together with evidence that poor and working-class communities are often more exposed to air pollution, these studies have stimulated discussion among scientists, policy makers, and the public about the differential distribution of the health impacts from air pollution. Science and public policy would benefit from additional research that integrates the theory and practice from both air pollution and social epidemiologies to gain a better understanding of this issue. In this article we aim to promote such research by introducing readers to methodologic and conceptual approaches in the fields of air pollution and social epidemiology; by proposing theories and hypotheses about how air pollution and socioeconomic factors may interact to influence health, drawing on studies conducted worldwide; by discussing methodologic issues in the design and analysis of studies to determine whether health effects of exposure to ambient air pollution are modified by SEP; and by proposing specific steps that will advance knowledge in this field, fill information gaps, and apply research results to improve public health in collaboration with affected communities. PMID:14644658

  4. Air pollution: Impact and prevention

    PubMed Central

    SIERRA-VARGAS, MARTHA PATRICIA; TERAN, LUIS M

    2012-01-01

    ABSTRACT Air pollution is becoming a major health problem that affects millions of people worldwide. In support of this observation, the World Health Organization estimates that every year, 2.4 million people die because of the effects of air pollution on health. Mitigation strategies such as changes in diesel engine technology could result in fewer premature mortalities, as suggested by the US Environmental Protection Agency. This review: (i) discusses the impact of air pollution on respiratory disease; (ii) provides evidence that reducing air pollution may have a positive impact on the prevention of disease; and (iii) demonstrates the impact concerted polices may have on population health when governments take actions to reduce air pollution. PMID:22726103

  5. Early life exposure to air pollution: how bad is it?

    PubMed

    Backes, Carl H; Nelin, Timothy; Gorr, Matthew W; Wold, Loren E

    2013-01-10

    Increasing concentrations of air pollution have been shown to contribute to an enormity of adverse health outcomes worldwide, which have been observed in clinical, epidemiological, and animal studies as well as in vitro investigations. Recently, studies have shown that air pollution can affect the developing fetus via maternal exposure, resulting in preterm birth, low birth weight, growth restriction, and potentially adverse cardiovascular and respiratory outcomes. This review will provide a summary of the harmful effects of air pollution exposure on the developing fetus and infant, and suggest potential mechanisms to limit the exposure of pregnant mothers and infants to air pollution. PMID:23164674

  6. Early Life Exposure to Air Pollution: How Bad Is It?

    PubMed Central

    Backes, Carl H.; Nelin, Timothy; Gorr, Matthew W.; Wold, Loren E.

    2012-01-01

    Increasing concentrations of air pollution have been shown to contribute to an enormity of adverse health outcomes worldwide, which have been observed in clinical, epidemiological, and animal studies as well as in vitro investigations. Recently, studies have shown that air pollution can affect the developing fetus via maternal exposure, resulting in preterm birth, low birth weight, growth restriction, and potentially adverse cardiovascular and respiratory outcomes. This review will provide a summary of the harmful effects of air pollution exposure on the developing fetus and infant, and suggest potential mechanisms to limit the exposure of pregnant mothers and infants to air pollution. PMID:23164674

  7. Comparing toxic air pollutant programs

    SciTech Connect

    Hawkins, S.C.

    1997-05-01

    This article compares state and federal toxic air pollutant programs. The Clean Air Act Ammendments created a program for the control of Hazardous Air Pollutants based on the establishment of control technology standards. State toxic programs can be classified into two categories: control technology-based and ambient concentration-based. Many states have opened to implement the MACT standards while enforcing their own state air toxics programs. Specific topics discussed include the following: the Federal air toxics program; existing state regulations; New Jersey Air Toxic Program; New York Toxics program.

  8. Air pollution and plant life

    SciTech Connect

    Treshow, M.

    1984-01-01

    This book addresses air pollution's sources and movement; biochemical, cellular, and whole-plant effects, impacts on agricultural and natural systems; and control. The effects of convective turbulence and atmospheric stability are well illustrated. The diagnosis of air pollution injury to plants and mimicking symptoms are discussed. The environmental and source variables that affect pollutant dispersion are explained by use of the Gaussian dispersion model. An overview is presented of the effects of sulfur dioxide, photochemical oxidants, and fluoride on stomatal function, photosynthesis, respiration, and metabolic processes and products. Information is discussed concerning combinations of air pollutants, impacts on lichens, and effects of trace metals on plants. The relationship between air pollutants and diseases or other stress factors is evaluated.

  9. [Air pollution, climate change and health].

    PubMed

    Ballester, Ferran

    2005-01-01

    Emissions into the atmosphere related to the climate change may further worsen the effects which air pollution has on the health of our citizens, not only indirectly due to the impact of weather phenomenon, but directly, due to the direct effects pollutants have on health. However, the efforts throughout most of the world have been aimed at dealing with these two problems separately for too many years. In fact, it is very often believed that the climate's health-safeguarding benefits would be achieved in the long term. To the contrary, what has become obvious over recent years is that the actions for reducing the emissions of polluting gases could redound in beneficial effects in the short term due to the reduction of the impact of air pollutants on the health of our citizens. This article presents the possible risks of the pollutants most closely related to climate changes, such as ozone and fine particles. Bearing in mind the uncertainties and unknowns related to this subject, the main implications for the policies related to this matter in Spain, as well as the needs for research are set out herein. In this regard, both from the standpoint of monitoring as well as research, it is considered necessary for an epidemiological monitoring system of the effects of air pollution and the relationship thereof to global changes to be established. PMID:15913052

  10. Atmospheric Chemistry and Air Pollution

    DOE PAGESBeta

    Gaffney, Jeffrey S.; Marley, Nancy A.

    2003-01-01

    Atmospheric chemistry is an important discipline for understanding air pollution and its impacts. This mini-review gives a brief history of air pollution and presents an overview of some of the basic photochemistry involved in the production of ozone and other oxidants in the atmosphere. Urban air quality issues are reviewed with a specific focus on ozone and other oxidants, primary and secondary aerosols, alternative fuels, and the potential for chlorine releases to amplify oxidant chemistry in industrial areas. Regional air pollution issues such as acid rain, long-range transport of aerosols and visibility loss, and the connections of aerosols to ozonemore » and peroxyacetyl nitrate chemistry are examined. Finally, the potential impacts of air pollutants on the global-scale radiative balances of gases and aerosols are discussed briefly.« less

  11. Air Pollution Primer. Revised Education.

    ERIC Educational Resources Information Center

    Corman, Rena

    This revised and updated book is written to inform the citizens on the nature, causes, and effects of air pollution. It is written in terms familiar to the layman with the purpose of providing knowledge and motivation to spur community action on clean air policies. Numerous charts and drawings are provided to support discussion of air pollution…

  12. Health effects of particulate air pollution: time for reassessment?

    PubMed Central

    Pope, C A; Bates, D V; Raizenne, M E

    1995-01-01

    Numerous studies have observed health effects of particulate air pollution. Compared to early studies that focused on severe air pollution episodes, recent studies are more relevant to understanding health effects of pollution at levels common to contemporary cities in the developed world. We review recent epidemiologic studies that evaluated health effects of particulate air pollution and conclude that respirable particulate air pollution is likely an important contributing factor to respiratory disease. Observed health effects include increased respiratory symptoms, decreased lung function, increased hospitalizations and other health care visits for respiratory and cardiovascular disease, increased respiratory morbidity as measured by absenteeism from work or school or other restrictions in activity, and increased cardiopulmonary disease mortality. These health effects are observed at levels common to many U.S. cities including levels below current U.S. National Ambient Air Quality Standards for particulate air pollution. Images Figure 1. PMID:7656877

  13. Study of air pollutant detectors

    NASA Technical Reports Server (NTRS)

    Gutshall, P. L.; Bowles, C. Q.

    1974-01-01

    The application of field ionization mass spectrometry (FIMS) to the detection of air pollutants was investigated. Current methods are reviewed for measuring contaminants of fixed gases, sulfur compounds, nitrogen oxides, hydrocarbons, and particulates. Two enriching devices: the dimethyl silicone rubber membrane separator, and the selective adsorber of polyethylene foam were studied along with FIMS. It is concluded that the membrane enricher system is not a suitable method for removing air pollutants. However, the FIMS shows promise as a useable system for air pollution detection.

  14. Air Pollution Exposure Assessment for Epidemiologic Studies of Pregnant Women and Children: Lessons Learned from the Centers for Children’s Environmental Health and Disease Prevention Research

    PubMed Central

    Gilliland, Frank; Avol, Ed; Kinney, Patrick; Jerrett, Michael; Dvonch, Timothy; Lurmann, Frederick; Buckley, Timothy; Breysse, Patrick; Keeler, Gerald; de Villiers, Tracy; McConnell, Rob

    2005-01-01

    The National Children’s Study is considering a wide spectrum of airborne pollutants that are hypothesized to potentially influence pregnancy outcomes, neurodevelopment, asthma, atopy, immune development, obesity, and pubertal development. In this article we summarize six applicable exposure assessment lessons learned from the Centers for Children’s Environmental Health and Disease Prevention Research that may enhance the National Children’s Study: a) Selecting individual study subjects with a wide range of pollution exposure profiles maximizes spatial-scale exposure contrasts for key pollutants of study interest. b) In studies with large sample sizes, long duration, and diverse outcomes and exposures, exposure assessment efforts should rely on modeling to provide estimates for the entire cohort, supported by subject-derived questionnaire data. c) Assessment of some exposures of interest requires individual measurements of exposures using snapshots of personal and microenvironmental exposures over short periods and/or in selected microenvironments. d) Understanding issues of spatial–temporal correlations of air pollutants, the surrogacy of specific pollutants for components of the complex mixture, and the exposure misclassification inherent in exposure estimates is critical in analysis and interpretation. e) “Usual” temporal, spatial, and physical patterns of activity can be used as modifiers of the exposure/outcome relationships. f) Biomarkers of exposure are useful for evaluation of specific exposures that have multiple routes of exposure. If these lessons are applied, the National Children’s Study offers a unique opportunity to assess the adverse effects of air pollution on interrelated health outcomes during the critical early life period. PMID:16203261

  15. Ambient air pollution: an emerging risk factor for diabetes mellitus.

    PubMed

    Rao, Xiaoquan; Montresor-Lopez, Jessica; Puett, Robin; Rajagopalan, Sanjay; Brook, Robert D

    2015-06-01

    Growing evidence supports that air pollution has become an important risk factor for developing diabetes mellitus. Understanding the contributing effect of air pollution in population studies, elucidating the potential mechanisms involved, and identifying the most responsible pollutants are all required in order to promulgate successful changes in policy and to help formulate preventive measures in an effort to reduce the risk for diabetes. This review summarizes recent findings from epidemiologic studies and mechanistic insights that provide links between exposure to air pollution and a heightened risk for diabetes. PMID:25894943

  16. Ambient and household air pollution: complex triggers of disease

    PubMed Central

    Farmer, Stephen A.; Nelin, Timothy D.; Falvo, Michael J.

    2014-01-01

    Concentrations of outdoor air pollution are on the rise, particularly due to rapid urbanization worldwide. Alternatively, poor ventilation, cigarette smoke, and other toxic chemicals contribute to rising concentrations of indoor air pollution. The World Health Organization recently reported that deaths attributable to indoor and outdoor air pollutant exposure are more than double what was originally documented. Epidemiological, clinical, and animal data have demonstrated a clear connection between rising concentrations of air pollution (both indoor and outdoor) and a host of adverse health effects. During the past five years, animal, clinical, and epidemiological studies have explored the adverse health effects associated with exposure to both indoor and outdoor air pollutants throughout the various stages of life. This review provides a summary of the detrimental effects of air pollution through examination of current animal, clinical, and epidemiological studies and exposure during three different periods: maternal (in utero), early life, and adulthood. Additionally, we recommend future lines of research while suggesting conceivable strategies to curb exposure to indoor and outdoor air pollutants. PMID:24929855

  17. Air Pollution Affects Community Health

    ERIC Educational Resources Information Center

    Shy, Carl M.; Finklea, John F.

    1973-01-01

    Community Health and Environmental Surveillance System (CHESS), a nationwide program relating community health to environmental quality, is designed to evaluate existing environmental standards, obtain health intelligence for new standards, and document health benefits of air pollution control. (BL)

  18. Western forests and air pollution

    SciTech Connect

    Olson, R.K.; Binkley, D.; Boehm, M.

    1992-01-01

    The book addresses the relationships between air pollution in the western United States and trends in the growth and condition of Western coniferous forests. The major atmospheric pollutants to which forest in the region are exposed are sulfur and nitrogen compounds and ozone. The potential effects of atmospheric pollution on these forests include foliar injury, alteration of growth rates and patterns, soil acidification, shifts in species composition, and modification of the effects of natural stresses.

  19. Air pollution injury to plants

    SciTech Connect

    Seibert, R.J.

    1986-01-01

    The injuries to plants by oxidant air pollution can be used as biological indicators of pollution episodes. Bel W3 tobacco is often used as an indicator organism. Dogwood is another potential indicator organism. Specific growing procedures used for indicator organisms are described, as are diagnostic criteria for the type and extent of injuries.

  20. Hazardous Air Pollutants

    MedlinePlus

    ... menu Learn the Issues Air Chemicals and Toxics Climate Change Emergencies Greener Living Health and Safety Land and Cleanup Pesticides Waste Water Science & Technology Air Climate Change Ecosystems Health Land, Waste and Cleanup Pesticides Substances ...

  1. Indoor air pollution

    SciTech Connect

    Not Available

    1985-05-01

    This factsheet reviews what is currently known about pollutant sources, abatement and control equipment and techniques for poorly ventilated houses. Radon, formaldehyde, tobacco smokes, carbon dioxide, carbon monoxide, particulates, bacteria, fungi and viruses are addressed. (PSB)

  2. Photochemically Altered Air Pollution Mixtures and Contractile Parameters in Isolated Murine Hearts before and after Ischemia.

    EPA Science Inventory

    Background: Epidemiological and toxicological studies support a causative link between ambient air pollution exposure and increased cardiovascular morbidity and mortality. While the adverse health effects of single pollutants are documented, little is known of the health effects...

  3. Title III hazardous air pollutants

    SciTech Connect

    Todd, R.

    1995-12-31

    The author presents an overview of the key provisions of Title III of the Clean Air Act Amendments of 1990. The key provisions include the following: 112(b) -- 189 Hazardous Air Pollutants (HAP); 112(a) -- Major Source: 10 TPY/25 TPY; 112(d) -- Application of MACT; 112(g) -- Modifications; 112(I) -- State Program; 112(j) -- The Hammer; and 112(r) -- Accidental Release Provisions.

  4. AIR POLLUTION AND RESPIRATORY DISEASE

    EPA Science Inventory

    Concern about polluted air in our urban and industrial areas began gathering momentum shortly after World War II. At that time it seemed obvious that clean air, like clean water, clean food, and a clean body, was a worth while goal in itself, requiring no further justification. B...

  5. Air Pollution as a Risk Factor for Type 2 Diabetes

    PubMed Central

    Rao, Xiaoquan; Patel, Priti; Puett, Robin; Rajagopalan, Sanjay

    2015-01-01

    Recent studies in both humans and animals suggest that air pollution is an important risk factor for type 2 diabetes mellitus (T2DM). However, the mechanism by which air pollution mediates propensity to diabetes is not fully understood. While a number of epidemiologic studies have shown a positive association between ambient air pollution exposure and risk for T2DM, some studies have not found such a relationship. Experimental studies in susceptible disease models do support this association and suggest the involvement of tissues involved in the pathogenesis of T2DM such as the immune system, adipose, liver, and central nervous system. This review summarizes the epidemiologic and experimental evidence between ambient outdoor air pollution and T2DM. PMID:25628401

  6. Environmental pollutants and breast cancer: epidemiologic studies.

    PubMed

    Brody, Julia Green; Moysich, Kirsten B; Humblet, Olivier; Attfield, Kathleen R; Beehler, Gregory P; Rudel, Ruthann A

    2007-06-15

    Laboratory research has shown that numerous environmental pollutants cause mammary gland tumors in animals; are hormonally active, specifically mimicking estrogen, which is a breast cancer risk factor; or affect susceptibility of the mammary gland to carcinogenesis. An assessment of epidemiologic research on these pollutants identified in toxicologic studies can guide future research and exposure reduction aimed at prevention. The PubMed database was searched for relevant literature and systematic critical reviews were entered in a database available at URL: www.silentspring.org/sciencereview and URL: www.komen.org/environment (accessed April 10, 2007). Based on a relatively small number of studies, the evidence to date generally supports an association between breast cancer and polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs) in conjunction with certain genetic polymorphisms involved in carcinogen activation and steroid hormone metabolism. Evidence regarding dioxins and organic solvents is sparse and methodologically limited but suggestive of an association. Methodologic problems include inadequate exposure assessment, a lack of access to highly exposed and unexposed populations, and a lack of preclinical markers to identify associations that may be obscured by disease latency. Among chemicals identified in toxicologic research as relevant to breast cancer, many have not been investigated in humans. The development of better exposure assessment methods is needed to fill this gap. In the interim, weaknesses in the epidemiologic literature argue for greater reliance on toxicologic studies to develop national policies to reduce chemical exposures that may be associated with breast cancer. Substantial research progress in the last 5 years suggests that the investigation of environmental pollutants will lead to strategies to reduce breast cancer risk. PMID:17503436

  7. Air pollution source identification

    NASA Technical Reports Server (NTRS)

    Fordyce, J. S.

    1975-01-01

    The techniques available for source identification are reviewed: remote sensing, injected tracers, and pollutants themselves as tracers. The use of the large number of trace elements in the ambient airborne particulate matter as a practical means of identifying sources is discussed. Trace constituents are determined by sensitive, inexpensive, nondestructive, multielement analytical methods such as instrumental neutron activation and charged particle X-ray fluorescence. The application to a large data set of pairwise correlation, the more advanced pattern recognition-cluster analysis approach with and without training sets, enrichment factors, and pollutant concentration rose displays for each element is described. It is shown that elemental constituents are related to specific source types: earth crustal, automotive, metallurgical, and more specific industries. A field-ready source identification system based on time and wind direction resolved sampling is described.

  8. Air Pollution in the World's Megacities.

    ERIC Educational Resources Information Center

    Richman, Barbara T., Ed.

    1994-01-01

    Reports findings of the Global Environment Monitoring System study concerning air pollution in the world's megacities. Discusses sources of air pollution, air pollution impacts, air quality monitoring, air quality trends, and control strategies. Provides profiles of the problem in Beijing, Los Angeles, Mexico City, India, Cairo, Sao Paulo, and…

  9. Associations between criteria air pollutants and asthma.

    PubMed Central

    Koren, H S

    1995-01-01

    The evidence that asthma is increasing in prevalence is becoming increasingly compelling. This trend has been demonstrated not only in the United States, but also in the United Kingdom, New Zealand, Australia, and several other Western countries. In the United States, the increase is largest in the group under 18 years of age. There is mounting evidence that certain environmental air pollutants are involved in exacerbating asthma. This is based primarily on epidemiologic studies and more recent clinical studies. The U.S. Clean Air Act of 1970 provides special consideration to the class of outdoor air pollutants referred to as criteria pollutants, including O3, sulfur dioxide (SO2), particulate matter (PM), NOx, CO, and Pb. Standards for these pollutants are set by the U.S. Environmental Protection Agency with particular concern for populations at risk. Current evidence suggests that asthmatics are more sensitive to the effects of O3, SO2, PM, and NO2, and are therefore at risk. High SO2 and particulate concentrations have been associated with short-term increases in morbidity and mortality in the general population during dramatic air pollution episodes in the past. Controlled exposure studies have clearly shown that asthmatics are sensitive to low levels of SO2. Exercising asthmatics exposed to SO2 develop bronchoconstriction within minutes, even at levels of 0.25 ppm. Responses are modified by air temperature, humidity, and exercise level. Recent epidemiologic studies have suggested that exposure to PM is strongly associated with morbidity and mortality in the general population and that hospital admissions for bronchitis and asthma were associated with PM10 levels. In controlled clinical studies, asthmatics appear to be no more reactive to aerosols than healthy subjects. Consequently, it is difficult to attribute the increased mortality observed in epidemiologic studies to specific effects demonstrated in controlled human studies. Epidemiologic studies of

  10. Air pollution exposure: Who is at high risk?

    NASA Astrophysics Data System (ADS)

    Peled, Ronit

    2011-04-01

    This article reviews the sub-population groups who are at high risk and first to be harmed by air pollution coming from anthropogenic combustions. Epidemiological studies from the last few decades contributed to the understanding of the different levels of susceptibility to air pollution. Older people and young infants, people who suffer from allergies, pulmonary and heart diseases, pregnant women and newborn babies, and deprived populations that suffer from low socio-economic status have all been described as populations at risk. A better understanding of the role of air pollution on large as well as specific populations' health, will promote a better protection policy.

  11. Health impact of air pollution to children.

    PubMed

    Sram, Radim J; Binkova, Blanka; Dostal, Miroslav; Merkerova-Dostalova, Michaela; Libalova, Helena; Milcova, Alena; Rossner, Pavel; Rossnerova, Andrea; Schmuczerova, Jana; Svecova, Vlasta; Topinka, Jan; Votavova, Hana

    2013-08-01

    differential expression of 104 genes. Specifically, biological processes related to immune and defense response were down-regulated in Ceske Budejovice. Our studies demonstrate that air pollution significantly affect child health. Especially noticeable is the increase of respiratory morbidity. With the development of molecular epidemiology, we can further evaluate the health risk of air pollution using biomarkers. PMID:23312845

  12. [Air pollution and population health].

    PubMed

    Kristoforović-Ilić, Miroslava; Ilić, Miroslav

    2006-10-01

    In the last few decades, there has been increased population concern for quality of environment, for it is, after life style, the second risk factor of disease development. Particular problem is that a large majority of serious impairments of health is manifested only after a long latent period, so it is not always possible to establish clear association with environmental factors. It is considered today that around 40% of lethal cases are caused by polluted environment in various ways, while environment is the most important etiologic factor in 5% of disease incidence. Problems arising due to environment pollution are most frequently related to air pollution. The World Resource Institute, Washington, has developed the indicators for evaluation of risk of environment pollution to population health. There is one common indicator both for developed and developing countries--air pollution. EPA recommended new standards for some polluting substances. The document reviewed these standards and their implementation in our community. New Law on Environment Protection ("Official Gazette of RS" No. 135/2004) from December 20th, 2004, followed by relevant documents on air quality, should be beneficial to experts at the level of subtle diagnostics and proposal of adequate measures with a view to improve the quality of life. PMID:18172966

  13. Contemporary threats and air pollution

    NASA Astrophysics Data System (ADS)

    Hopke, Philip K.

    It is now well understood that air pollution produces significant adverse health effects in the general public and over the past 60 years, there have been on-going efforts to reduce the emitted pollutants and their resulting health effects. There are now shifting patterns of industrialization with many heavily polluting industries moving from developed countries with increasingly stringent air quality standards to the developing world. However, even in decreasing concentrations of pollutants, health effects remain important possibly as a result of changes in the nature of the pollutants as new chemicals are produced and as other causes of mortality and morbidity are reduced. In addition, there is now the potential for deliberate introduction of toxic air pollutants by local armed conflicts and terrorists. Thus, there are new challenges to understand the role of the atmospheric environment on public health in this time of changing economic and demographic conditions overlaid with the willingness to indirectly attack governments and other established entities through direct attacks on the general public.

  14. Air pollution and plant life

    SciTech Connect

    Treshow, M.

    1984-01-01

    The publication of this volume could hardly have been more timely, for concern about the damage to plants from air pollution has grown rapidly in the last few years. The book comprises eighteen chapters by contributors of high repute. Three early chapters deal with Dispersion and Fate of Atmospheric Pollutants, Long Range Transport and Monitoring Levels and Effects of Air Pollutants. They provide essential reading for those working on effects in the field, and they set the scene for a contribution from the Volume Editor on the problems of diagnosis. The central chapters (7 to 11) provide, in considerable depth, a summary of the knowledge of the mechanism of action of pollutants on plants, in terms of physiology, biochemistry, and ultrastructure. Particularly valuable is the essay entitled Impact of Air Pollutant Combinations on Plants, which concludes that even though few generalizations are possible, there is now sufficient evidence to suggest that interactions between some pollutants (e.g. SO/sub 2/ and O/sub 3/, SO/sub 2/ and NO/sub 2/) may seriously damage some plants.

  15. Air Quality Modeling of Traffic-related Air Pollutants for the NEXUS Study

    EPA Science Inventory

    The paper presents the results of the model applications to estimate exposure metrics in support of an epidemiologic study in Detroit, Michigan. A major challenge in traffic-related air pollution exposure studies is the lack of information regarding pollutant exposure characteriz...

  16. In Brief: Air pollution app

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2010-10-01

    A new smartphone application takes advantage of various technological capabilities and sensors to help users monitor air quality. Tapping into smartphone cameras, Global Positioning System (GPS) sensors, compasses, and accelerometers, computer scientists with the University of Southern California's (USC) Viterbi School of Engineering have developed a new application, provisionally entitled “Visibility.” Currently available for the Android telephone operating system, the application is available for free download at http://robotics.usc.edu/˜mobilesensing/Projects/AirVisibilityMonitoring. An iPhone application may be introduced soon. Smartphone users can take a picture of the sky and then compare it with models of sky luminance to estimate visibility. While conventional air pollution monitors are costly and thinly deployed in some areas, the smartphone application potentially could help fill in some blanks in existing air pollution maps, according to USC computer science professor Gaurav Sukhatme.

  17. Molecular epidemiology of severe ambient air pollution on women and the developing fetus. Progress report, 15 September 1993--14 September 1994

    SciTech Connect

    Perera, F.P.

    1994-09-01

    The research goal is validation of a number of promising biomarkers in two groups of Polish women and their newborn infants: 73 mother/child pairs from Krakow, a city with elevated air pollution and 90 pairs from Limanowa, a less polluted area. Specifically, the authors are evaluating: (1) the relationship between ambient exposures and the following markers of biologically effective dose and biologic response: PAH-DNA adducts by enzyme-linked immunosorbent assay (ELISA) polycyclic aromatic hydrocarbon-DNA adducts by {sup 32}P-postlabeling and the frequency of gene mutation at the hprt locus in T-lymphocytes; (2) the relationship between markers of biologically effective dose (adducts) and markers of biologic response (gene mutation); (3) the comparison of the same biomarkers in maternal and fetal/newborn tissues to assess possible differences in response and susceptibility; (4) the ability of genetic/metabolic markers (CYP1A1 mRNA, CYP1A1 enzyme activity, CYP1A1 MspI polymorphism and glutathione-S-transferase (GSTM1) genotype) to modify markers of biologically effective dose and biologic response, including an estimate of host versus environmental contributions; and (5) the relationship between biomarkers (PAH-DNA adducts and serum cotinine) to birth weight.

  18. Phytotoxicity of Air Pollutants

    PubMed Central

    Olszyk, David M.; Tingey, David T.

    1984-01-01

    Pisum sativum L. cv Alsweet (garden pea) and Lycopersicon esculentum flacca Mill. (tomato) were used to evaluate the phytotoxicity of SO2 and O3 in the light and dark. Plants were grown in controlled environment chambers and exposed to SO2 or O3 in the light or dark at the same environmental conditions at which they were grown. The pea plants were treated with fusicoccin to ensure open stomata in the dark; the stomata of the tomato mutant remained open in the dark. Both species exhibited 64% to 80% less foliar necrosis following exposure to SO2 (0.5 to 1.0 microliter per liter for 2 hours) in the light than in the dark. The decrease in SO2 injury for light versus dark exposed plants was greater in fully expanded than expanding leaves. Both species exhibited 30% greater foliar necrosis following exposure to O3 (0.2 microliter per liter for 2 hours) in the light than dark. The increase in O3 injury in the light versus dark was similar for leaves at all stages of expansion. Leaf conductance to water vapor was 7% to 11% and 23% higher in the light than dark for fusicoccin-treated peas and tomato plants, respectively, indicating greater foliar uptake of both pollutants in the light than dark. Thus, the decreased SO2 toxicity in the light was not associated with pollutant uptake, but rather the metabolism of SO2. In contrast, the increased toxicity of O3 in the light was at least in part associated with increased uptake or could not be separated from it. PMID:16663549

  19. ECONOMICS AND PERFORMANCE MODELING (AIR POLLUTION TECHNOLOGY BRANCH, AIR POLLUTION PREVENTION AND CONTROL DIVISION, NRMRL)

    EPA Science Inventory

    NRMRL's Air Pollution Prevention and Control Division's Air Pollution Technology Branch (APTB) is active in the development, refinement, and maintenance of economic and performance evaluation models that provide agency-wide support for estimating costs for air pollution preventio...

  20. Air Pollution Control, Part II.

    ERIC Educational Resources Information Center

    Strauss, Werner, Ed.

    This book contains five major articles in areas of current importance in air pollution control. They are written by authors who are actively participating in the areas on which they report. It is the aim of each article to completely cover theory, experimentation, and practice in the field discussed. The contents are as follows: Emissions,…

  1. Physician's Guide to Air Pollution.

    ERIC Educational Resources Information Center

    Weisburd, Mel

    Prepared at the request of the American Medical Association Council on Environmental and Public Health, this pamphlet on air pollution is one of a series of publications published by the Council as part of its continuing responsibility to provide current information on environmental health problems to the physician, the medical society, the…

  2. Air Pollution. Part A: Analysis.

    ERIC Educational Resources Information Center

    Ledbetter, Joe O.

    Two facets of the engineering control of air pollution (the analysis of possible problems and the application of effective controls) are covered in this two-volume text. Part A covers Analysis, and Part B, Prevention and Control. (This review is concerned with Part A only.) This volume deals with the terminology, methodology, and symptomatology…

  3. Health Effects of Air Pollution.

    ERIC Educational Resources Information Center

    Environmental Education Report and Newsletter, 1985

    1985-01-01

    Summarizes health hazards associated with air pollution, highlighting the difficulty in establishing acceptable thresholds of exposure. Respiratory disease, asthma, cancer, cardiovascular disease, and other problems are addressed. Indicates that a wide range of effects from any one chemical exists and that there are differences in sensitivity to…

  4. Solid Waste, Air Pollution and Health

    ERIC Educational Resources Information Center

    Kupchik, George J.; Franz, Gerald J.

    1976-01-01

    This article examines the relationships among solid waste disposal, air pollution, and human disease. It is estimated that solid waste disposal contributes 9.7 percent of the total air pollution and 9.9 percent of the total air pollution health effect. Certain disposal-resource recovery systems can be implemented to meet air quality standards. (MR)

  5. MICA-AIR: A PARTICIPANT-BASED APPROACH TO EXPOSURE ASSESSMENT IN EPIDEMIOLOGIC AND COMMUNITY HEALTH STUDIES

    EPA Science Inventory

    Objective. Epidemiologic and community health studies of traffic-related air pollution and childhood asthma have been limited by resource intensive exposure assessment techniques. The current study utilized a novel participant-based approach to collect air monitoring data f...

  6. Mild Air Pollution of Concern in Pregnancy

    MedlinePlus

    ... https://medlineplus.gov/news/fullstory_158558.html Mild Air Pollution of Concern in Pregnancy Study found risk for ... Being exposed to just a small amount of air pollution during pregnancy ups the risk of a pregnancy ...

  7. AIR POLLUTION CONTROL TECHNOLOGIES (CHAPTER 65)

    EPA Science Inventory

    The chapter discusses the use of technologies for reducing air pollution emissions from stationary sources, with emphasis on the control of combustion gen-erated air pollution. Major stationary sources include utility power boilers, industrial boilers and heaters, metal smelting ...

  8. Air Pollution and Heart Disease, Stroke

    MedlinePlus

    ... Pressure High Blood Pressure Tools & Resources Stroke More Air Pollution and Heart Disease, Stroke Updated:Aug 30,2016 ... or Longer-Term Acute short-term effects of air pollution tend to strike people who are elderly or ...

  9. Mild Air Pollution of Concern in Pregnancy

    MedlinePlus

    ... nih.gov/medlineplus/news/fullstory_158558.html Mild Air Pollution of Concern in Pregnancy Study found risk for ... Being exposed to just a small amount of air pollution during pregnancy ups the risk of a pregnancy ...

  10. Clean Air Slots Amid Atmospheric Pollution

    NASA Technical Reports Server (NTRS)

    Hobbs, Peter V.

    2002-01-01

    This article investigates the mechanism for those layers in the atmosphere that are free of air borne pollution even though the air above and below them carry pollutants. Atmospheric subsidence is posed as a mechanism for this phenomenon.

  11. Characterization of ambient air pollution for stochastic health models

    SciTech Connect

    Batterman, S.A.

    1981-08-01

    This research is an analysis of various measures of ambient air pollution useful in cross-sectional epidemiological investigations and rick assessments. The Chestnut Ridge area health effects investigation, which includes a cross-sectional study of respiratory symptoms in young children, is used as a case study. Four large coal-fired electric generating power plants are the dominant pollution sources in this area of western Pennsylvania. The air pollution data base includes four years of sulfur dioxide and five years of total suspended particulate concentrations at seventeen monitors. Some 70 different characterizations of pollution are constructed and tested. These include pollutant concentrations at various percentiles and averaging times, exceedence measures which show the amount of time a specified threshold concentration is exceeded, and several dosage measures which transform non-linear dose-response relationships onto pollutant concentrations.

  12. Regional air pollution over Malaysia

    NASA Astrophysics Data System (ADS)

    Krysztofiak, G.; Catoire, V.; Dorf, M.; Grossmann, K.; Hamer, P. D.; Marécal, V.; Reiter, A.; Schlager, H.; Eckhardt, S.; Jurkat, T.; Oram, D.; Quack, B.; Atlas, E.; Pfeilsticker, K.

    2012-12-01

    During the SHIVA (Stratospheric Ozone: Halogen Impacts in a Varying Atmosphere) campaign in Nov. and Dec. 2011 a number of polluted air masses were observed in the marine and terrestrial boundary layer (0 - 2 km) and in the free troposphere (2 - 12 km) over Borneo/Malaysia. The measurements include isoprene, CO, CO2, CH4, N2O, NO2, SO2 as primary pollutants, O3 and HCHO as secondary pollutants, and meteorological parameters. This set of trace gases can be used to fingerprint different sources of local and regional air pollution (e.g., biomass burning and fossil fuel burning, gas flaring on oil rigs, emission of ships and from urban areas, volcanic emissions, and biogenic emissions). Individual sources and location can be identified when the measurements are combined with a nested-grid regional scale chemical and meteorological model and lagrangian particle dispersion model (e.g., CCATT-BRAMS and FLEXPART). In the case of the former, emission inventories of the primary pollutants provide the basis for the trace gas simulations. In this region, the anthropogenic influence on air pollution seems to dominate over natural causes. For example, CO2 and CH4 often show strong correlations with CO, suggesting biomass burning or urban fossil fuel combustion dominates the combustion sources. The study of the CO/CO2 and CH4/CO ratios can help separate anthropogenic combustion from biomass burning pollution sources. In addition, these ratios can be used as a measure of combustion efficiency to help place the type of biomass burning particular to this region within the wider context of fire types found globally. On several occasions, CH4 enhancements are observed near the ocean surface, which are not directly correlated with CO enhancements thus indicating a non-combustion-related CH4 source. Positive correlations between SO2 and CO show the anthropogenic influence of oil rigs located in the South China Sea. Furthermore, SO2 enhancements are observed without any increase in CO

  13. REGIONAL AIR POLLUTION STUDY, EMISSION INVENTORY SUMMARIZATION

    EPA Science Inventory

    As part of the Regional Air Pollution Study (RAPS), data for an air pollution emission inventory are summarized for point and area sources in the St. Louis Air Quality Control Region. Data for point sources were collected for criteria and noncriteria pollutants, hydrocarbons, sul...

  14. Air Pollution. Environmental Ecological Education Project.

    ERIC Educational Resources Information Center

    Parkway School District, Chesterfield, MO.

    This unit, designed for senior high school students, focuses on air pollution by examining its effect on man, plants and animals, the causes of air pollution, and possible solutions to the air pollution problems. It approaches each of these topics through both natural science and social science perspectives. The unit is divided into seven separate…

  15. Product Guide/1972 [Air Pollution Control Association].

    ERIC Educational Resources Information Center

    Journal of the Air Pollution Control Association, 1971

    1971-01-01

    Reprinted in this pamphlet is the fifth annual directory of air pollution control products as compiled in the "Journal of the Air Pollution Control Association" for December, 1971. The 16-page guide lists manufacturers of emission control equipment and air pollution instrumentation under product classifications as derived from McGraw-Hill's "Air…

  16. The Crisis in Air Pollution Manpower Development

    ERIC Educational Resources Information Center

    Moeller, Dade W.

    1974-01-01

    Three studies conducted by the National Air Pollution Manpower Development Advisory Committee concluded there is a crisis in air pollution manpower development within the United States today. The studies investigated the existing federal manpower program, air pollution educational requirements and the quality of graduate level university programs.…

  17. Air pollution ranks as largest health risk

    NASA Astrophysics Data System (ADS)

    Wendel, JoAnna

    2014-04-01

    The World Health Organization (WHO) reports that 7 million people died in 2012 from air-pollution-related sicknesses, marking air pollution as the single largest environmental health risk. This finding, a result of better knowledge and assessment of the diseases, is more than double previous estimates of the risk of death from air pollution.

  18. Pollution and skin: from epidemiological and mechanistic studies to clinical implications.

    PubMed

    Krutmann, Jean; Liu, Wei; Li, Li; Pan, Xiaochuan; Crawford, Martha; Sore, Gabrielle; Seite, Sophie

    2014-12-01

    In recent years, the health effects associated with air pollution have been intensively studied. Most studies focus on air pollution effects on the lung and the cardiovascular system. More recently, however, epidemiological and mechanistic studies suggest that air pollution is also affecting skin integrity. This state-of-the-art review focuses on this latter aspect; it was developed with the collaboration of European and Chinese board of experts with specific interests in environmental health, clinical and basic research in dermatology and cosmetic dermatology. A literature review limited to pollution and health effects and (sensitive) skin was performed using PubMed. Review and original articles were chosen. We summarize the existing scientific evidence that air pollution exerts detrimental effects on human skin, discuss potential clinical implications and suggest specific and unspecific cosmetic protective measures. PMID:25278222

  19. The Adverse Effects of Air Pollution on the Nervous System

    PubMed Central

    Genc, Sermin; Zadeoglulari, Zeynep; Fuss, Stefan H.; Genc, Kursad

    2012-01-01

    Exposure to ambient air pollution is a serious and common public health concern associated with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air pollution on the pulmonary and cardiovascular systems have been well established in a series of major epidemiological and observational studies. In the recent past, air pollution has also been associated with diseases of the central nervous system (CNS), including stroke, Alzheimer's disease, Parkinson's disease, and neurodevelopmental disorders. It has been demonstrated that various components of air pollution, such as nanosized particles, can easily translocate to the CNS where they can activate innate immune responses. Furthermore, systemic inflammation arising from the pulmonary or cardiovascular system can affect CNS health. Despite intense studies on the health effects of ambient air pollution, the underlying molecular mechanisms of susceptibility and disease remain largely elusive. However, emerging evidence suggests that air pollution-induced neuroinflammation, oxidative stress, microglial activation, cerebrovascular dysfunction, and alterations in the blood-brain barrier contribute to CNS pathology. A better understanding of the mediators and mechanisms will enable the development of new strategies to protect individuals at risk and to reduce detrimental effects of air pollution on the nervous system and mental health. PMID:22523490

  20. Air pollution and arrhythmic risk: the smog is yet to clear.

    PubMed

    Watkins, Alex; Danilewitz, Marlon; Kusha, Marjan; Massé, Stéphane; Urch, Bruce; Quadros, Kenneth; Spears, Danna; Farid, Talha; Nanthakumar, Kumaraswamy

    2013-06-01

    Epidemiologic evidence has demonstrated that air pollution may impair cardiovascular health, leading to potentially life-threatening arrhythmias. Efforts have been made, with the use of epidemiologic data and controlled exposures in diverse animal and human populations, to verify the relationship between air pollution and arrhythmias. The purpose of this review is to examine and contrast the epidemiologic and toxicologic evidence to date that relates airborne pollutants with cardiac arrhythmia. We have explored the potential biological mechanisms driving this association. Using the PubMed database, we conducted a literature search that included the terms "air pollution" and "arrhythmia" and eventually divergent synonyms such as "particulate matter," "bradycardia," and "atrial fibrillation." We reviewed epidemiologic studies and controlled human and animal exposures independently to determine whether observational conclusions were corroborated by toxicologic results. Numerous pollutants have demonstrated some arrhythmic capacity among healthy and health-compromised populations. However, some exposure studies have shown no significant correlation of air pollutants with arrhythmia, which suggests some uncertainty about the arrhythmogenic potential of air pollution and the mechanisms involved in arrhythmogenesis. While data from an increasing number of controlled exposures with human volunteers suggest a potential mechanistic link between air pollution and altered cardiac electrophysiology, definite conclusions regarding air pollution and arrhythmia are elusive as the direct arrhythmic effects of air pollutants are not entirely consistent across all studies. PMID:23219609

  1. Air Pollution and Control Legislation in India

    NASA Astrophysics Data System (ADS)

    P Bhave, Prashant; Kulkarni, Nikhil

    2015-09-01

    Air pollution in urban areas arises from multiple sources, which may vary with location and developmental activities. Anthropogenic activities as rampant industrialization, exploitation and over consumption of natural resources, ever growing population size are major contributors of air pollution. The presented review is an effort to discuss various aspects of air pollution and control legislation in India emphasizing on the history, present scenario, international treaties, gaps and drawbacks. The review also presents legislative controls with judicial response to certain landmark judgments related to air pollution. The down sides related to enforcement mechanism for the effective implementation of environmental laws for air pollution control have been highlighted.

  2. NOX CONTROL BY COMBUSTION MODIFICATION (AIR POLLUTION TECHNOLOGY BRANCH, AIR POLLUTION PREVENTION AND CONTROL DIVISION, NRMRL)

    EPA Science Inventory

    NRMRL's Air Pollution Prevention and Control Division's Air Pollution Technology Branch has performed research and developed technologies for NOx reduction via combustion modification. Techniques such as low-excess air firing, staged combustion, flue gas recirculation, low NOx bu...

  3. Pollutional haze and COPD: etiology, epidemiology, pathogenesis, pathology, biological markers and therapy

    PubMed Central

    Wang, Fei; Ni, Song-Shi

    2016-01-01

    In recent years, serious pollutional haze occurs in the mainland of China thanks to the development of urbanization and industrialization. There is a close relationship between air pollution and the occurrence and development of chronic obstructive pulmonary disease (COPD), but there are some new characteristics in some aspects of COPD associated with pollutional haze compared with COPD induced by traditional physical and chemical factors. This article attempts to summarize the new progress from these new features of COPD related to pollutional haze, focus on etiology, epidemiology, pathogenesis, pathology, biological markers and therapy. PMID:26904250

  4. Air pollution as a risk factor in lung cancer

    SciTech Connect

    Vena, J.E.

    1982-07-01

    Retrospective data on residential and employment history and on smoking were obtained from 417 white male lung cancer patients and 752 controls with nonrespiratory, nonneoplastic diseases, from Erie County, New York, admitted to Roswell Park Memorial Institute from 1957-1965. Total suspended particulate data and a historical review of problem point sources of pollution were used to delineate air pollution zones. The findings did not support the hypothesis that air pollution alone significantly increased risk for lung cancer. However, there was increased risk from smoking and occupational exposures if there was also long-term exposure to air pollution. The risk for heavy smokers with heavy exposure to air pollution was over four times that of men with none of the high exposure traits. The findings suggest an apparent synergistic mechanism involving smoking and air pollution and smoking and occupational exposures. The findings are consistent with previous epidemiologic studies and with biologic and experimental evidence. The limitations of the methods used here necessitate further study and replication. However, the study indicates that air pollution should not be dismissed as a risk factor in lung cancer.

  5. Air pollution threatens the health of children in China

    SciTech Connect

    Millman, A.; Tang, D.L.; Perera, F.P.

    2008-09-15

    China's rapid economic development has come at the cost of severe environmental degradation, most notably from coal combustion. Outdoor air pollution is associated with >300 000 deaths, 20 million cases of respiratory illness, and a health cost of >500 billion renminbi (>3% of gross domestic product) annually. The young are particularly susceptible to air pollution, yet there has been only limited recognition of its effects on children's health and development. To fill this gap, we reviewed relevant published environmental studies, biomedical and molecular/epidemiologic research, and economic and policy analyses. China relies on coal for about 70% to 75% of its energy needs, consuming 1.9 billion tons of coal each year. In addition to CO{sub 2}, the major greenhouse gas, coal burning in China emits vast quantities of particulate matter, polycyclic aromatic hydrocarbons, sulfur dioxide, arsenic, and mercury. Seventy percent of Chinese households burn coal or biomass for cooking and heating, which contaminates indoor air. Adverse effects of combustion-related air pollution include reduced fetal and child growth, pulmonary disease including asthma, developmental impairment, and increased risk of cancer. A prospective molecular epidemiologic study of newborns in Chongqing has demonstrated direct benefits to children's health and development from the elimination of a coal-burning plant. Recognition of the full health and economic cost of air pollution to Chinese children and the benefits of pollution reduction should spur increased use of renewable energy, energy efficiency, and clean-fuel vehicles. This is a necessary investment for China's future.

  6. Particulate matter air pollution and atherosclerosis.

    PubMed

    Brook, Robert D; Rajagopalan, Sanjay

    2010-09-01

    Particulate matter (PM) air pollution less than 2.5 microm in diameter (PM(2.5)), which is now an all-pervading element of modern-day society, is associated with heightened cardiovascular morbidity and mortality. Not only can short-term PM(2.5) exposure trigger acute cardiovascular events, but longer-term exposure over years augments cardiovascular risk to an even greater extent. One biological mechanism capable of explaining this observation is that chronic exposure may promote the progression and vulnerability of atherosclerotic plaques. Indeed, recent epidemiologic studies have demonstrated an association between ambient PM(2.5) exposure and the presence or extent of atherosclerosis in humans. Several animal experiments have provided corroborating evidence that chronic exposures in fact do enhance the progression and perhaps vulnerability of atherosclerotic lesions. Due to the billions of people continually exposed to PM(2.5), the long-term pro-atherosclerotic effects of this ubiquitous air pollutant are likely to be of enormous and growing global public health importance. PMID:20617466

  7. Air pollution measurements from satellites

    NASA Technical Reports Server (NTRS)

    Ludwig, C. B.; Griggs, M.; Malkmus, W.; Bartle, E. R.

    1973-01-01

    A study is presented on the remote sensing of gaseous and particulate air pollutants which is an extension of a previous report. Pollutants can be observed by either active or passive remote sensing systems. Calculations discussed herein indicate that tropospheric CO, CO2, SO2, NO2, NH3, HCHO, and CH4 can be measured by means of nadir looking passive systems. Additional species such as NO, HNO3, O3, and H2O may be measured in the stratosphere through a horizon experiment. A brief theoretical overview of resonance Raman scattering and resonance fluorescence is given. It is found that radiance measurements are most promising for general global applications, and that stratospheric aerosols may be measured using a sun occultation technique. The instrumentation requirements for both active and passive systems are examined and various instruments now under development are described.

  8. Evaluating sources of indoor air pollution

    SciTech Connect

    Tichenor, B.A.; Sparks, L.E.; White, J.B.; Jackson, M.D. )

    1988-01-01

    Scientists and engineers in the Indoor Air Brand of EPS'a Air and Energy Engineering Research Laboratory are conducting research to increase the state of knowledge concerning indoor air pollution factors. A three phase program is being implemented. The purpose of this paper is to show how their approach can be used to evaluate specific sources of indoor air pollution. Pollutants from two sources are examined: para-dichlorobenzene emissions from moth crystal cakes; and particulate emissions from unvented kerosene heaters.

  9. Effects of Exposure Measurement Error in the Analysis of Health Effects from Traffic-Related Air Pollution

    EPA Science Inventory

    In large epidemiological studies, many researchers use surrogates of air pollution exposure such as geographic information system (GIS)-based characterizations of traffic or simple housing characteristics. It is important to validate these surrogates against measured pollutant co...

  10. Environmental Chemistry: Air and Water Pollution.

    ERIC Educational Resources Information Center

    Stoker, H. Stephen; Seager, Spencer L.

    This is a book about air and water pollution whose chapters cover the topics of air pollution--general considerations, carbon monoxide, oxides of nitrogen, hydrocarbons and photochemical oxidants, sulfur oxides, particulates, temperature inversions and the greenhouse effect; and water pollution--general considerations, mercury, lead, detergents,…

  11. Development and evaluation of alternative approaches for exposure assessment of multiple air pollutants in Atlanta, Georgia

    EPA Science Inventory

    Measurements from central site (CS) monitors are often used as estimates of exposure in air pollution epidemiological studies. As these measurements are typically limited in their spatiotemporal resolution, true exposure variability within a population is often obscured, leading ...

  12. BIOAVAILABLE AIR PARTICULATE POLLUTION CONSTITUENTS DIRECTLY ALTER CARDIOVASCULAR FUNCTION EX VIVO

    EPA Science Inventory

    Epidemiological studies have reported associations between particulate air pollution exposure and cardiovascular (CV) effects within susceptible individuals. Particle characteristics and biological mechanisms responsible for these observations are not known. We examined whether s...

  13. AIR PARTICULATE POLLUTION CARDIOVASCULAR TOXICITY: HAZARD IDENTIFICATION AND MECHANISMS OF ACTION

    EPA Science Inventory


    The overall weight of evidence from epidemiological studies has shown statistical associations between air particulate pollution exposure and mortality\\morbidity particularly within individuals with cardiovascular disease (1-4). Identification of causal particle properties ...

  14. IDENTIFICATION OF FACTORS RESULTING IN SUSCEPTIBILITY TO THE EFFECTS OF AIR POLLUTANTS

    EPA Science Inventory

    Understanding the underlying physiological processes which may account for pollution-associated health effects is an important research priority for the EPA. Numerous epidemiologic time-series studies have shown generally consistent associations of outdoor (ambient) air pollutio...

  15. Cardiovascular Effects in Adults with Metabolic Syndrome Exposed to Concentrated Ultrafine Air Pollution Particles

    EPA Science Inventory

    RATIONALE: Epidemiologic studies report associations between ambient air pollution particulate matter (PM) and various indices of cardiopulmonary morbidity and mortality. A leading hypothesis contends that smaller ultrafine (UF) particles induce a greater physiologic response bec...

  16. Respiratory health effects of air pollution: update on biomass smoke and traffic pollution.

    PubMed

    Laumbach, Robert J; Kipen, Howard M

    2012-01-01

    Mounting evidence suggests that air pollution contributes to the large global burden of respiratory and allergic diseases, including asthma, chronic obstructive pulmonary disease, pneumonia, and possibly tuberculosis. Although associations between air pollution and respiratory disease are complex, recent epidemiologic studies have led to an increased recognition of the emerging importance of traffic-related air pollution in both developed and less-developed countries, as well as the continued importance of emissions from domestic fires burning biomass fuels, primarily in the less-developed world. Emissions from these sources lead to personal exposures to complex mixtures of air pollutants that change rapidly in space and time because of varying emission rates, distances from source, ventilation rates, and other factors. Although the high degree of variability in personal exposure to pollutants from these sources remains a challenge, newer methods for measuring and modeling these exposures are beginning to unravel complex associations with asthma and other respiratory tract diseases. These studies indicate that air pollution from these sources is a major preventable cause of increased incidence and exacerbation of respiratory disease. Physicians can help to reduce the risk of adverse respiratory effects of exposure to biomass and traffic air pollutants by promoting awareness and supporting individual and community-level interventions. PMID:22196520

  17. Respiratory Health Effects of Air Pollution: Update on Biomass Smoke and Traffic Pollution

    PubMed Central

    Laumbach, Robert J.; Kipen, Howard M.

    2012-01-01

    Mounting evidence suggests that air pollution contributes to the large global burden of respiratory and allergic diseases including asthma, chronic obstructive pulmonary disease, pneumonia and possibly tuberculosis. Although associations between air pollution and respiratory disease are complex, recent epidemiologic studies have led to an increased recognition of the emerging importance of traffic-related air pollution in both developed and less-developed countries, as well as the continued importance of emissions from domestic fires burning biomass fuels primarily in the less-developed world. Emissions from these sources lead to personal exposures to complex mixtures of air pollutants that change rapidly in space and time due to varying emission rates, distances from source, ventilation rates, and other factors. Although the high degree of variability in personal exposure to pollutants from these sources remains a challenge, newer methods for measuring and modeling these exposures are beginning to unravel complex associations with asthma and other respiratory disease. These studies indicate that air pollution from these sources is a major preventable cause of increased incidence and exacerbation of respiratory disease. Physicians can help to reduce the risk of adverse respiratory effects of exposure to biomass and traffic air pollutants by promoting awareness and supporting individual and community-level interventions. PMID:22196520

  18. CRITICAL HEALTH ISSUES OF CRITERIA AIR POLLUTANTS

    EPA Science Inventory

    This chapter summarizes the key health information on ubiquitous outdoor air pollutants that can cause adverse health effects at current or historical ambient levels in the United States. Of the thousands of air pollutants, very few meet this definition. The Clean Air Act (CA...

  19. Airplanes on Air Pollution: Discover-AQ

    NASA Video Gallery

    NASA's launching a new mission, summer 2011, designed to gather data on air pollution and help expand our understanding of how it affects us, and that could allow pollutants to be monitored more pr...

  20. Pigeons home faster through polluted air.

    PubMed

    Li, Zhongqiu; Courchamp, Franck; Blumstein, Daniel T

    2016-01-01

    Air pollution, especially haze pollution, is creating health issues for both humans and other animals. However, remarkably little is known about how animals behaviourally respond to air pollution. We used multiple linear regression to analyse 415 pigeon races in the North China Plain, an area with considerable air pollution, and found that while the proportion of pigeons successfully homed was not influenced by air pollution, pigeons homed faster when the air was especially polluted. Our results may be explained by an enhanced homing motivation and possibly an enriched olfactory environment that facilitates homing. Our study provides a unique example of animals' response to haze pollution; future studies are needed to identify proposed mechanisms underlying this effect. PMID:26728113

  1. Pigeons home faster through polluted air

    NASA Astrophysics Data System (ADS)

    Li, Zhongqiu; Courchamp, Franck; Blumstein, Daniel T.

    2016-01-01

    Air pollution, especially haze pollution, is creating health issues for both humans and other animals. However, remarkably little is known about how animals behaviourally respond to air pollution. We used multiple linear regression to analyse 415 pigeon races in the North China Plain, an area with considerable air pollution, and found that while the proportion of pigeons successfully homed was not influenced by air pollution, pigeons homed faster when the air was especially polluted. Our results may be explained by an enhanced homing motivation and possibly an enriched olfactory environment that facilitates homing. Our study provides a unique example of animals’ response to haze pollution; future studies are needed to identify proposed mechanisms underlying this effect.

  2. Pigeons home faster through polluted air

    PubMed Central

    Li, Zhongqiu; Courchamp, Franck; Blumstein, Daniel T.

    2016-01-01

    Air pollution, especially haze pollution, is creating health issues for both humans and other animals. However, remarkably little is known about how animals behaviourally respond to air pollution. We used multiple linear regression to analyse 415 pigeon races in the North China Plain, an area with considerable air pollution, and found that while the proportion of pigeons successfully homed was not influenced by air pollution, pigeons homed faster when the air was especially polluted. Our results may be explained by an enhanced homing motivation and possibly an enriched olfactory environment that facilitates homing. Our study provides a unique example of animals’ response to haze pollution; future studies are needed to identify proposed mechanisms underlying this effect. PMID:26728113

  3. REGIONAL AIR POLLUTION STUDY, NON-CRITERIA POLLUTANT INVENTORY

    EPA Science Inventory

    In conjunction with the Regional Air Pollution Study (RAPS) being conducted in the St. Louis Air Quality Control Region (AQCR), an inventory of non-criteria pollutants was assembled for point sources. The inventory was based on the following data: (1) The National Emissions Data ...

  4. Hazardous air pollutants and asthma.

    PubMed Central

    Leikauf, George D

    2002-01-01

    Asthma has a high prevalence in the United States, and persons with asthma may be at added risk from the adverse effects of hazardous air pollutants (HAPs). Complex mixtures (fine particulate matter and tobacco smoke) have been associated with respiratory symptoms and hospital admissions for asthma. The toxic ingredients of these mixtures are HAPs, but whether ambient HAP exposures can induce asthma remains unclear. Certain HAPs are occupational asthmagens, whereas others may act as adjuncts during sensitization. HAPs may exacerbate asthma because, once sensitized, individuals can respond to remarkably low concentrations, and irritants lower the bronchoconstrictive threshold to respiratory antigens. Adverse responses after ambient exposures to complex mixtures often occur at concentrations below those producing effects in controlled human exposures to a single compound. In addition, certain HAPs that have been associated with asthma in occupational settings may interact with criteria pollutants in ambient air to exacerbate asthma. Based on these observations and past experience with 188 HAPs, a list of 19 compounds that could have the highest impact on the induction or exacerbation of asthma was developed. Nine additional compounds were identified that might exacerbate asthma based on their irritancy, respirability, or ability to react with biological macromolecules. Although the ambient levels of these 28 compounds are largely unknown, estimated exposures from emissions inventories and limited air monitoring suggest that aldehydes (especially acrolein and formaldehyde) and metals (especially nickel and chromium compounds) may have possible health risk indices sufficient for additional attention. Recommendations for research are presented regarding exposure monitoring and evaluation of biologic mechanisms controlling how these substances induce and exacerbate asthma. PMID:12194881

  5. Perspective on Air Pollution: The Canadian Scene

    PubMed Central

    Shephard, R. J.

    1975-01-01

    Despite the large ratio of land mass to population, Canada has significant air pollution problems, some being due to our cold climate, the long arctic nights, and a mineral-based economy. Routes of intoxication include the respiration of polluted air and the secondary contamination of food and water. Although pollution is often measured in terms of industrial emissions, the physician must be concerned rather with the dose of pollutants to which the individual is exposed. The principal air pollutants, in terms of emitted tonnage, are carbon monoxide, sulfur dioxide, hydrocarbons, particulates, and oxides of nitrogen. Sources of these various materials are discussed. PMID:20469224

  6. Omega-3 Fatty Acid Supplementation Appears to Attenuate Particulate Air Pollution-induced Cardiac Effects and Lipid Changes in Healthy Middle-aged Adults.

    EPA Science Inventory

    Context: Air pollution exposure has been associated with adverse cardiovascular effects. A recent epidemiologic study reported that omega-3 fatty acid (fish oil) supplementation blunted the cardiac responses to air pollution exposure. Objective: To evaluate in a randomized contro...

  7. Hybrid regional air pollution models

    SciTech Connect

    Drake, R.L.

    1980-03-01

    This discussion deals with a family of air quality models for predicting and analyzing the fine particulate loading in the atmosphere, for assessing the extent and degree of visibility impairment, and for determining the potential of pollutants for increasing the acidity of soils and water. The major horizontal scales of interest are from 400km to 2000km; and the time scales may vary from several hours, to days, weeks, and a few months or years, depending on the EPA regulations being addressed. First the role air quality models play in the general family of atmospheric simulation models is described. Then, the characteristics of a well-designed, comprehensive air quality model are discussed. Following this, the specific objectives of this workshop are outlined, and their modeling implications are summarized. There are significant modeling differences produced by the choice of the coordinate system, whether it be the fixed Eulerian system, the moving Lagrangian system, or some hybrid of the two. These three systems are briefly discussed, and a list of hybrid models that are currently in use are given. Finally, the PNL regional transport model is outlined and a number of research needs are listed.

  8. EPA's indoor air/pollution prevention workshop

    SciTech Connect

    Leovic, K.W.; White, J.B.; Sarsony, C.

    1993-01-01

    The paper discusses a workshop held as a step toward EPA's prioritizing potential areas of research for applying pollution prevention to indoor air quality (IAQ). The workshop involved technical experts in the fields of IAQ, pollution prevention, and selected industries. Workshop goals were to identify major IAQ issues and their pollution prevention opportunities, and to suggest research strategies for IAQ/pollution prevention. The paper summarizes the suggestions made by workshop participants and highlights opportunities for IAQ/pollution prevention research.

  9. Risk assessment of urban air pollution.

    PubMed

    Törnqvist, M; Ehrenberg, L

    1992-12-01

    Urban air pollution, originating in western countries mainly from automotive engine exhausts, contains thousands of components, many of which are genotoxic, i.e. are putative cancer initiators. Other pollution components, such as NO2 and certain particles, may have cocarcinogenic/promotive effects, at least at higher exposure levels. Cancer risk assessment of this complex mixture has to combine data from the exposure history, from epidemiological studies as well as from animal carcinogenicity tests, and from in vitro studies of fractions and individual components. Data for metabolism and pharmaco-kinetics have also to be considered. A multiplicative linear model is assumed to be valid for cancer initiation at low levels. Attempts are being made to determine the target dose from ultimate carcinogens (reactive metabolites) via macromolecule adduct levels, and to base the risk assessment on the radiation-dose equivalent to the chemical dose. So far this has been possible only for simple alkenes, which are metabolized to epoxides, and indirectly, via benzo(a)pyrene (BaP), for particle-bound polycyclic aromatic hydrocarbons (PAH). The lifetime risk of cancer (all sites) from ethene is estimated accordingly to 1.4 x 10(-4) per microgram m-3, and from PAH to 12 x 10(-4) per ng m-3 BaP. For other components indicated to give risk contribution (NOx, volatile PAH, benzene, aldehydes, butadiene) essential data are lacking and only very rough estimates can be given at this time. PMID:1306130

  10. Air pollution: a potentially modifiable risk factor for lung cancer.

    PubMed

    Fajersztajn, Laís; Veras, Mariana; Barrozo, Ligia Vizeu; Saldiva, Paulo

    2013-09-01

    Economic growth and increased urbanization pose a new risk for cancer development: the exposure of high numbers of people to ambient air pollution. Epidemiological evidence that links air pollution to mortality from lung cancer is robust. An ability to produce high-quality scientific research that addresses these risks and the ability of local health authorities to understand and respond to these risks are basic requirements to solve the conflict between economic development and the preservation of human health. However, this is currently far from being achieved. Thus, this Science and Society article addresses the possibilities of expanding scientific networking to increase awareness of the risk of lung cancer that is promoted by air pollution. PMID:23924644

  11. AIR POLLUTION TECHNOLOGY BRANCH (AIR POLLUTION PREVENTION AND CONTROL DIVISION, NRMRL)

    EPA Science Inventory

    Fundamental and applied combustion research has been conducted by the Air Pollution Prevention and Control Division's Air Pollution Technology Branch (APTB)and its predecessors since EPA's inception. APTB has been instrumental in the development and successful application of flue...

  12. COOPERATIVE RESEARCH (AIR POLLUTION TECHNOLOGY BRANCH, AIR POLLUTION PREVENTION AND CONTROL DIVISION, NRMRL)

    EPA Science Inventory

    NRMRL's Air Pollution Prevention and Control Division's Air Pollution Technology Branch (APTB) is always interested in the potential for cooperative research if overlap occurs between the research goals of external organizations and APTB's research goals.APTB has participated i...

  13. PUBLICATIONS (AIR POLLUTION TECHNOLOGY BRANCH, AIR POLLUTION PREVENTION AND CONTROL DIVISION, NRMRL)

    EPA Science Inventory

    The Air Pollution Technology Branch (APTB) of NRMRL's Air Pollution Prevention and Control Division produces and publishes highly specialized technical and scientific documents related to APTB's research. Areas of research covered include artificial intelligence, CFC destruction,...

  14. OUTDOOR AIR POLLUTION AND DNA DAMAGE

    EPA Science Inventory

    Although working outdoors has frequently been considered more healthful than working indoors, a growing literature suggests that outdoor air exposures increase the risk for a variety of diseases, such as asthma, heart disease, and lung cancer). Consistent with these epidemiologic...

  15. A semi-automated system for quantifying the oxidative potential of ambient particles in aqueous extracts using the dithiothreitol (DTT) assay: results from the Southeastern Center for Air Pollution and Epidemiology (SCAPE)

    NASA Astrophysics Data System (ADS)

    Fang, T.; Verma, V.; Guo, H.; King, L. E.; Edgerton, E. S.; Weber, R. J.

    2014-07-01

    A variety of methods are used to measure the capability of particulate matter (PM) to catalytically generate reactive oxygen species (ROS) in vivo, also defined as the aerosol oxidative potential. A widely used measure of aerosol oxidative potential is the dithiothreitol (DTT) assay, which monitors the depletion of DTT (a surrogate for cellular antioxidants) as catalyzed by the redox-active species in PM. However, a major constraint in the routine use of the DTT assay for integrating it with the large-scale health studies is its labor-intensive and time-consuming protocol. To specifically address this concern, we have developed a semi-automated system for quantifying the oxidative potential of aerosol liquid extracts using the DTT assay. The system, capable of unattended analysis at one sample per hour, has a high analytical precision (Coefficient of Variation of 12% for standards, 4% for ambient samples), and reasonably low limit of detection (0.31 nmol min-1). Comparison of the automated approach with the manual method conducted on ambient samples yielded good agreement (slope = 1.08 ± 0.12, r2 = 0.92, N = 9). The system was utilized for the Southeastern Center for Air Pollution and Epidemiology (SCAPE) to generate an extensive data set on DTT activity of ambient particles collected from contrasting environments (urban, road-side, and rural) in the southeastern US. We find that water-soluble PM2.5 DTT activity on a per air volume basis was spatially uniform and often well correlated with PM2.5 mass (r = 0.49 to 0.88), suggesting regional sources contributing to the PM oxidative potential in southeast US. However, the greater heterogeneity in the intrinsic DTT activity (per PM mass basis) across seasons indicates variability in the DTT activity associated with aerosols from sources that vary with season. Although developed for the DTT assay, the instrument can also be used to determine oxidative potential with other acellular assays.

  16. INTEGRATED AIR POLLUTION CONTROL SYSTEM (IAPCS) COST MODEL (AIR POLLUTION TECHNOLOGY BRANCH, AIR POLLUTION PREVENTION AND CONTROL DIVISION, NRMRL)

    EPA Science Inventory

    The Air Pollution Technology Branch's (APPCD, NRMRL) Integrated Air Pollution Control System Cost Model is a compiled model written in FORTRAN and C language that is designed to be used on an IBM or compatible PC with 640K or lower RAM and at least 1.5 Mb of hard drive space. It ...

  17. Combined air and water pollution control system

    NASA Technical Reports Server (NTRS)

    Wolverton, Billy C. (Inventor); Jarrell, Lamont (Inventor)

    1990-01-01

    A bioaquatic air pollution control system for controlling both water and atmospheric pollution is disclosed. The pollution control system includes an exhaust for directing polluted gases out of a furnace and a fluid circulating system which circulates fluid, such as waste water, from a source, past the furnace where the fluid flow entrains the pollutants from the furnace. The combined fluid and pollutants are then directed through a rock/plant/microbial filtering system. A suction pump pumps the treated waste water from the filter system past the exhaust to again entrain more pollutants from the furnace where they are combined with the fluid (waste water) and directed to the filter system.

  18. APEX (Air Pollution Exercise) Volume 3: Air Pollution Control Officer's Manual.

    ERIC Educational Resources Information Center

    Environmental Protection Agency, Research Triangle Park, NC. Office of Manpower Development.

    The Air Pollution Control Officer's (APCO) Manual is part of a set of 21 manuals (AA 001 009-001 029) used in APEX (Air Pollution Exercise) a computerized college and professional level "real world" game simulation of a community with urban and rural problems, industrial activities, and air pollution difficulties, The first two sections, which are…

  19. APEX (Air Pollution Exercise) Volume 21: Legal References: Air Pollution Control Regulations.

    ERIC Educational Resources Information Center

    Environmental Protection Agency, Research Triangle Park, NC. Office of Manpower Development.

    The Legal References: Air Pollution Control Regulations Manual is the last in a set of 21 manuals (AA 001 009-001 029) used in APEX (Air Pollution Exercise), a computerized college and professional level "real world" game simulation of a community with urban and rural problems, industrial activities, and air pollution difficulties. The manual…

  20. Air Quality in Lanzhou, a Major Industrial City in China: Characteristics of Air Pollution and Review of Existing Evidence from Air Pollution and Health Studies

    PubMed Central

    Zhang, Yaqun; Li, Min; Bravo, Mercedes A.; Jin, Lan; Nori-Sarma, Amruta; Xu, Yanwen; Guan, Donghong; Wang, Chengyuan; Chen, Mingxia; Wang, Xiao; Tao, Wei; Qiu, Weitao; Zhang, Yawei

    2015-01-01

    Air pollution contributes substantially to global health burdens; however, less is known about pollution patterns in China and whether they differ from those elsewhere. We evaluated temporal and spatial heterogeneity of air pollution in Lanzhou, an urban Chinese city (April 2009–December 2012), and conducted a systematic review of literature on air pollution and health in Lanzhou. Average levels were 141.5, 42.3, and 47.2 µg/m3 for particulate matter with an aerodynamic diameter ≤10 µm (PM10), NO2, and SO2, respectively. Findings suggest some seasonality, particularly for SO2, with higher concentrations during colder months relative to warmer months, although a longer time frame of data is needed to evaluate seasonality fully. Correlation coefficients generally declined with distance between monitors, while coefficients of divergence increased with distance. However, these trends were not statistically significant. PM10 levels exceeded Chinese and other health-based standards and guidelines. The review identified 13 studies on outdoor air pollution and health. Although limited, the studies indicate that air pollution is associated with increased risk of health outcomes in Lanzhou. These studies and the high air pollution levels suggest potentially serious health consequences. Findings can provide guidance to future epidemiological studies, monitor placement programs, and air quality policies. PMID:25838615

  1. Air Pollution and Its Control, Second Edition.

    ERIC Educational Resources Information Center

    Sproull, Wayne T.

    A concise appraisal of our contemporary status and future prospects with regard to air pollution and its control are offered in this text for concerned laymen. What air pollution is, how it endangers health, the cost of controlling it, what is being done about it now, and what should be done are some of the basic questions considered. Topics cover…

  2. Measurement of Air Pollutants in the Troposphere

    ERIC Educational Resources Information Center

    Clemitshaw, Kevin C.

    2011-01-01

    This article describes the principles, applications and performances of methods to measure gas-phase air pollutants that either utilise passive or active sampling with subsequent laboratory analysis or involve automated "in situ" sampling and analysis. It focuses on air pollutants that have adverse impacts on human health (nitrogen dioxide, carbon…

  3. Career Guide for Air Pollution Control

    ERIC Educational Resources Information Center

    Baldwin, Lionel V.

    1975-01-01

    This guide to career opportunities in air pollution control includes resource information in this area and provides a listing of colleges and universities offering environmental science programs. The guide was prepared by the S-11 Education and Training Committee of the Air Pollution Control Association. (Author/BT)

  4. Controlling Indoor Air Pollution from Moxibustion

    PubMed Central

    Lu, Chung-Yen; Kang, Sy-Yuan; Liu, Shu-Hui; Mai, Cheng-Wei; Tseng, Chao-Heng

    2016-01-01

    Indoor air quality (IAQ) control of hospitals plays a critical role in protecting both hospital staffs and patients, particularly those who are highly susceptible to the adverse effects of indoor noxious hazards. However, moxibustion in outpatient departments (OPDs) of traditional Chinese medicine (TCM) may be a source of indoor air pollution in hospitals. Some studies have investigated indoor air pollution during moxibustion in Chinese medicine clinics (CMCs) and moxibustion rooms, demonstrating elevated air pollutants that pose a threat to the health of medical staff and patients. Our study investigated the indoor air pollutants of indoor carbon dioxide (CO2), carbon monoxide (CO), formaldehyde (HCHO), total volatile organic compounds (TVOCs), airborne particulate matter with a diameter of ≤10 µm (PM10) and ≤2.5 µm (PM2.5) during moxibustion in an acupuncture and moxibustion room of the OPD in a hospital in Taipei. To evaluate the different control strategies for indoor air pollution from moxibution, a comparison of air pollutants during moxibution among the methods of using alternative old moxa wools, local exhaust ventilation and an air cleaner was conducted. In this study, burning alternative old moxa wools for moxibustion obviously reduced all gaseous pollutants except for aerosols comparing burning fresh moxa wools. Using local exhaust ventilation reduced most of the aerosols after burning moxa. We also found that using an air cleaner was inefficient for controlling indoor air pollutants, particularly gaseous pollutants. Therefore, combining replacing alternative old moxa wools and local exhaust ventilation could be a suitable design for controlling indoor air pollution during moxibustion therapy. PMID:27331817

  5. Controlling Indoor Air Pollution from Moxibustion.

    PubMed

    Lu, Chung-Yen; Kang, Sy-Yuan; Liu, Shu-Hui; Mai, Cheng-Wei; Tseng, Chao-Heng

    2016-01-01

    Indoor air quality (IAQ) control of hospitals plays a critical role in protecting both hospital staffs and patients, particularly those who are highly susceptible to the adverse effects of indoor noxious hazards. However, moxibustion in outpatient departments (OPDs) of traditional Chinese medicine (TCM) may be a source of indoor air pollution in hospitals. Some studies have investigated indoor air pollution during moxibustion in Chinese medicine clinics (CMCs) and moxibustion rooms, demonstrating elevated air pollutants that pose a threat to the health of medical staff and patients. Our study investigated the indoor air pollutants of indoor carbon dioxide (CO₂), carbon monoxide (CO), formaldehyde (HCHO), total volatile organic compounds (TVOCs), airborne particulate matter with a diameter of ≤10 µm (PM10) and ≤2.5 µm (PM2.5) during moxibustion in an acupuncture and moxibustion room of the OPD in a hospital in Taipei. To evaluate the different control strategies for indoor air pollution from moxibution, a comparison of air pollutants during moxibution among the methods of using alternative old moxa wools, local exhaust ventilation and an air cleaner was conducted. In this study, burning alternative old moxa wools for moxibustion obviously reduced all gaseous pollutants except for aerosols comparing burning fresh moxa wools. Using local exhaust ventilation reduced most of the aerosols after burning moxa. We also found that using an air cleaner was inefficient for controlling indoor air pollutants, particularly gaseous pollutants. Therefore, combining replacing alternative old moxa wools and local exhaust ventilation could be a suitable design for controlling indoor air pollution during moxibustion therapy. PMID:27331817

  6. Air pollution and circulating biomarkers of oxidative stress

    PubMed Central

    Staimer, Norbert; Vaziri, Nosratola D.

    2013-01-01

    Chemical components of air pollutant exposures that induce oxidative stress and subsequent inflammation may be partly responsible for associations of cardiovascular morbidity and mortality with airborne particulate matter and combustion-related pollutant gasses. However, epidemiologic evidence regarding this is limited. An exposure-assessment approach is to measure the oxidative potential of particle mixtures because it is likely that hundreds of correlated chemicals are involved in overall effects of air pollution on health. Oxidative potential likely depends on particle composition and size distribution, especially ultrafine particle concentration, and on transition metals and certain semivolatile and volatile organic chemicals. For health effects, measuring systemic oxidative stress in the blood is one feasible approach, but there is no universal biomarker of oxidative stress and there are many potential target molecules (lipids, proteins, DNA, nitric oxide, etc.), which may be more or less suitable for specific study goals. Concurrent with the measurement of oxidative stress, it is important to measure gene and/or protein expression of endogenous antioxidant enzymes because they can modify relations between oxidative stress biomarkers and air pollutants. Conversely, the expression and activities of these enzymes are modified by oxidative stress. This interplay will likely determine the observed effects of air pollutants on systemic inflammatory and thrombotic mediators and related clinical outcomes. Studies are needed to assess the reliability and validity of oxidative stress biomarkers, evaluate differences in associations between oxidative stress biomarkers and various pollutant measurements (mass, chemical components, and oxidative potential), and evaluate impacts of antioxidant responses on these relations. PMID:23626660

  7. Outdoor air pollution in urban areas and allergic respiratory diseases.

    PubMed

    D'Amato, G

    1999-12-01

    Respiratory allergic diseases (rhinitis, rhinosinusitis, bronchial asthma and its equivalents) appear to be increasing in most countries, and subjects living in urban and industrialized areas are more likely to experience respiratory allergic symptoms than those living in rural areas. This increase has been linked, among various factors, to air pollution, which is now an important public health hazard. Laboratory studies confirm the epidemiological evidence that inhalation of some pollutants, either individually or in combination, adversely affect lung function in asthmatics. The most abundant air pollutants in urban areas with high levels of vehicle traffic are respirable particulate matter, nitrogen dioxide and ozone. While nitrogen dioxide does not exert consistent effects on lung function, ozone, respirable particulate matter and allergens impair lung function and lead to increased airway responsiveness and bronchial obstruction in predisposed subjects. However, besides acting as irritants, airborne pollutants can modulate the allergenicity of antigens carried by airborne particles. By attaching to the surface of pollen grains and of plant-derived paucimicronic particles, pollutants can modify the morphology of these antigen-carrying agents and after their allergenic potential. In addition, by inducing airway inflammation, which increases airway epithelial permeability, pollutants overcome the mucosal barrier and so facilitate the allergen-induced inflammatory responses. Moreover, air pollutants such as diesel exhaust emissions are thought to modulate the immune response by increasing immunoglobulin E synthesis, thus facilitating allergic sensitization in atopic subjects and the subsequent development of clinical respiratory symptoms. PMID:10695313

  8. Air Pollution: Mechanisms of Neuroinflammation & CNS Disease

    PubMed Central

    Block, Michelle L.; Calderón-Garcidueñas, Lilian

    2009-01-01

    Emerging evidence implicates air pollution as a chronic source of neuroinflammation, reactive oxygen species (ROS), and neuropathology instigating central nervous system (CNS) disease. Stroke incidence, and Alzheimer’s and Parkinson’s disease pathology are linked to air pollution. Recent reports reveal that air pollution components reach the brain. Further, systemic effects known to impact lung and cardiovascular disease also impinge upon CNS health. While mechanisms driving air pollution-induced CNS pathology are poorly understood, new evidence suggests that activation of microglia and changes in the blood brain barrier may be key to this process. Here, we summarize recent findings detailing the mechanisms through which air pollution reaches the brain and activates the resident innate immune response to become a chronic source of pro-inflammatory factors and ROS culpable in CNS disease. PMID:19716187

  9. Urban air pollution, poverty, violence and health--Neurological and immunological aspects as mediating factors.

    PubMed

    Kristiansson, Marianne; Sörman, Karolina; Tekwe, Carmen; Calderón-Garcidueñas, Lilian

    2015-07-01

    Rapid rural-urban migration has created overcrowded areas characterized by concentrated poverty and increases in indoor and outdoor air pollutants. These "hotspots" constitute an increased risk of violence and disease outbreaks. We hypothesize that the effects of poverty and associated air pollution-related stress on impaired cognitive skills are mediated by inflammatory cytokines. A research framework is proposed, encompassing (i) an epidemiological investigation of associations between poverty, high concentrations of air pollutants, violence and health, (ii) a longitudinal follow-up of working memory capacities and inflammatory markers, and (iii) intervention programs aiming to strengthen employability and decreased exposures to toxic air pollutants. PMID:26005121

  10. AIR POLLUTION, INFLAMMATION AND PRETERM BIRTH: A POTENTIAL MECHANISTIC LINK

    PubMed Central

    Vadillo-Ortega, Felipe; Osornio-Vargas, Alvaro; Buxton, Miatta A.; Sánchez, Brisa N.; Rojas-Bracho, Leonora; Viveros-Alcaráz, Martin; Castillo-Castrejón, Marisol; Beltrán-Montoya, Jorge; Brown, Daniel G.; O´Neill, Marie S.

    2014-01-01

    Preterm birth is a public health issue of global significance, which may result in mortality during the perinatal period or may lead to major health and financial consequences due to lifelong impacts. Even though several risk factors for preterm birth have been identified, prevention efforts have failed to halt the increasing rates of preterm birth. Epidemiological studies have identified air pollution as an emerging potential risk factor for preterm birth. However, many studies were limited by study design and inadequate exposure assessment. Due to the ubiquitous nature of ambient air pollution and the potential public health significance of any role in causing preterm birth, a novel focus investigating possible causal mechanisms influenced by air pollution is therefore a global health priority. We hypothesize that air pollution may act together with other biological factors to induce systemic inflammation and influence the duration of pregnancy. Evaluation and testing of this hypothesis is currently being conducted in a prospective cohort study in Mexico City and will provide an understanding of the pathways that mediate the effects of air pollution on preterm birth. The important public health implication is that crucial steps in this mechanistic pathway can potentially be acted on early in pregnancy to reduce the risk of preterm birth. PMID:24382337

  11. Air Pollution and Environmental Justice Awareness

    NASA Astrophysics Data System (ADS)

    Bouvier-Brown, N. C.

    2014-12-01

    Air pollution is not equally dispersed in all neighborhoods and this raises many social concerns, such as environmental justice. "Real world" data, whether extracted from online databases or collected in the field, can be used to demonstrate air quality patterns. When students explore these trends, they not only learn about atmospheric chemistry, but they also become socially aware of any inequities. This presentation outlines specific ways to link air pollution and environmental justice suitable for an undergraduate upper division Air Pollution or Atmospheric Chemistry course.

  12. Controlled Exposures to Air Pollutants and Risk of Cardiac Arrhythmia

    PubMed Central

    Watts, Simon J.; Hunter, Amanda J.; Shah, Anoop S.V.; Bosson, Jenny A.; Unosson, Jon; Barath, Stefan; Lundbäck, Magnus; Cassee, Flemming R.; Donaldson, Ken; Sandström, Thomas; Blomberg, Anders; Newby, David E.; Mills, Nicholas L.

    2014-01-01

    Background: Epidemiological studies have reported associations between air pollution exposure and increases in cardiovascular morbidity and mortality. Exposure to air pollutants can influence cardiac autonomic tone and reduce heart rate variability, and may increase the risk of cardiac arrhythmias, particularly in susceptible patient groups. Objectives: We investigated the incidence of cardiac arrhythmias during and after controlled exposure to air pollutants in healthy volunteers and patients with coronary heart disease. Methods: We analyzed data from 13 double-blind randomized crossover studies including 282 participants (140 healthy volunteers and 142 patients with stable coronary heart disease) from whom continuous electrocardiograms were available. The incidence of cardiac arrhythmias was recorded for each exposure and study population. Results: There were no increases in any cardiac arrhythmia during or after exposure to dilute diesel exhaust, wood smoke, ozone, concentrated ambient particles, engineered carbon nanoparticles, or high ambient levels of air pollution in either healthy volunteers or patients with coronary heart disease. Conclusions: Acute controlled exposure to air pollutants did not increase the short-term risk of arrhythmia in participants. Research employing these techniques remains crucial in identifying the important pathophysiological pathways involved in the adverse effects of air pollution, and is vital to inform environmental and public health policy decisions. Citation: Langrish JP, Watts SJ, Hunter AJ, Shah AS, Bosson JA, Unosson J, Barath S, Lundbäck M, Cassee FR, Donaldson K, Sandström T, Blomberg A, Newby DE, Mills NL. 2014. Controlled exposures to air pollutants and risk of cardiac arrhythmia. Environ Health Perspect 122:747–753; http://dx.doi.org/10.1289/ehp.1307337 PMID:24667535

  13. Ambient particulate air pollution and ectopy - The Environmental Epidemiology of Arrhythmogenesis in Women’s Health Initiative Study, 1999-2004

    PubMed Central

    Liao, Duanping; Whitsel, Eric A.; Duan, Yinkang; Lin, Hung-Mo; Quibrera, P. Miguel; Smith, Richard; Peuquet, Donna J.; Prineas, Ronald J.; Zhang, Zhu-Ming; Anderson, Garnet

    2008-01-01

    The relationships between ambient PM2.5 and PM10 and arrhythmia and the effect modification by cigarette smoking were investigated. Data from EPA air quality monitors and an established national-scale, log-normal kriging method were used to spatially estimate daily mean concentrations of PM at addresses of 57,422 individuals from 59 examination sites in 24 US states in 1999-2004. The acute and subacute exposures were estimated as mean, geocoded address-specific PM concentrations on the day of, 0-2 days before, and averaged over 30 days before the ECG (Lag0; Lag1; Lag2; Lag1-30). At the time of standard 12-lead resting ECG, the mean age (SD) of participants was 67.5 (6.9) years (84% non-Hispanic White; 6% current smoker; 15% with coronary heart disease; 5% with ectopy). After the identification of significant effect modifiers, two-stage random-effects models were used to calculate center-pooled odds ratios and 95% confidence intervals (OR, 95% CI) of arrhythmia per 10 μg/m3 increase in PM concentrations. Among current smokers, Lag0 and Lag1 PM concentrations were significantly associated ventricular ectopy (VE) - the OR (95% CI) for VE among current smokers was 2 (1.32-3.3) and 1.32 (1.07-1.65) at Lag1 PM2.5 and PM10, respectively. The interactions between current smoking and acute exposures (Lag0; Lag1; Lag2) were significant in relationship to VE. Acute exposures were not significantly associated with supraventricular ectopy (SVE), or with VE among non-smokers. Subacute (Lag1-30) exposures were not significantly associated with arrhythmia. Acute PM2.5 and PM10 exposure is directly associated with the odds of VE among smokers, suggesting that they are more vulnerable to the arrhythmogenic effects of PM. PMID:18979352

  14. Air pollutant production by algal cell cultures

    NASA Technical Reports Server (NTRS)

    Fong, F.; Funkhouser, E. A.

    1982-01-01

    The production of phytotoxic air pollutants by cultures of Chlorella vulgaris and Euglena gracilis is considered. Algal and plant culture systems, a fumigation system, and ethylene, ethane, cyanide, and nitrogen oxides assays are discussed. Bean, tobacco, mustard green, cantaloupe and wheat plants all showed injury when fumigated with algal gases for 4 hours. Only coleus plants showed any resistance to the gases. It is found that a closed or recycled air effluent system does not produce plant injury from algal air pollutants.

  15. Air pollution and the respiratory system.

    PubMed

    Arbex, Marcos Abdo; Santos, Ubiratan de Paula; Martins, Lourdes Conceição; Saldiva, Paulo Hilário Nascimento; Pereira, Luiz Alberto Amador; Braga, Alfésio Luis Ferreira

    2012-01-01

    Over the past 250 years-since the Industrial Revolution accelerated the process of pollutant emission, which, until then, had been limited to the domestic use of fuels (mineral and vegetal) and intermittent volcanic emissions-air pollution has been present in various scenarios. Today, approximately 50% of the people in the world live in cities and urban areas and are exposed to progressively higher levels of air pollutants. This is a non-systematic review on the different types and sources of air pollutants, as well as on the respiratory effects attributed to exposure to such contaminants. Aggravation of the symptoms of disease, together with increases in the demand for emergency treatment, the number of hospitalizations, and the number of deaths, can be attributed to particulate and gaseous pollutants, emitted by various sources. Chronic exposure to air pollutants not only causes decompensation of pre-existing diseases but also increases the number of new cases of asthma, COPD, and lung cancer, even in rural areas. Air pollutants now rival tobacco smoke as the leading risk factor for these diseases. We hope that we can impress upon pulmonologists and clinicians the relevance of investigating exposure to air pollutants and of recognizing this as a risk factor that should be taken into account in the adoption of best practices for the control of the acute decompensation of respiratory diseases and for maintenance treatment between exacerbations. PMID:23147058

  16. Physical activity, air pollution and the brain.

    PubMed

    Bos, Inge; De Boever, Patrick; Int Panis, Luc; Meeusen, Romain

    2014-11-01

    This review introduces an emerging research field that is focused on studying the effect of exposure to air pollution during exercise on cognition, with specific attention to the impact on concentrations of brain-derived neurotrophic factor (BDNF) and inflammatory markers. It has been repeatedly demonstrated that regular physical activity enhances cognition, and evidence suggests that BDNF, a neurotrophin, plays a key role in the mechanism. Today, however, air pollution is an environmental problem worldwide and the high traffic density, especially in urban environments and cities, is a major cause of this problem. During exercise, the intake of air pollution increases considerably due to an increased ventilation rate and particle deposition fraction. Recently, air pollution exposure has been linked to adverse effects on the brain such as cognitive decline and neuropathology. Inflammation and oxidative stress seem to play an important role in inducing these health effects. We believe that there is a need to investigate whether the well-known benefits of regular physical activity on the brain also apply when physical activity is performed in polluted air. We also report our findings about exercising in an environment with ambient levels of air pollutants. Based on the latter results, we hypothesize that traffic-related air pollution exposure during exercise may inhibit the positive effect of exercise on cognition. PMID:25119155

  17. Spatial air pollution modelling for a West-African town.

    PubMed

    Gebreab, Sirak Zenebe; Vienneau, Danielle; Feigenwinter, Christian; Bâ, Hâmpaté; Cissé, Guéladio; Tsai, Ming-Yi

    2015-01-01

    Land use regression (LUR) modelling is a common approach used in European and Northern American epidemiological studies to assess urban and traffic related air pollution exposures. Studies applying LUR in Africa are lacking. A need exists to understand if this approach holds for an African setting, where urban features, pollutant exposures and data availability differ considerably from other continents. We developed a parsimonious regression model based on 48-hour nitrogen dioxide (NO2) concentrations measured at 40 sites in Kaédi, a medium sized West-African town, and variables generated in a geographic information system (GIS). Road variables and settlement land use characteristics were found to be important predictors of 48-hour NO2 concentration in the model. About 68% of concentration variability in the town was explained by the model. The model was internally validated by leave-one-out cross-validation and it was found to perform moderately well. Furthermore, its parameters were robust to sampling variation. We applied the model at 100 m pixels to create a map describing the broad spatial pattern of NO2 across Kaédi. In this research, we demonstrated the potential for LUR as a valid, cost-effective approach for air pollution modelling and mapping in an African town. If the methodology were to be adopted by environmental and public health authorities in these regions, it could provide a quick assessment of the local air pollution burden and potentially support air pollution policies and guidelines. PMID:26618306

  18. Climate Change and Air Pollution: Effects on Respiratory Allergy

    PubMed Central

    Pawankar, Ruby; Vitale, Carolina; Lanza, Maurizia; Molino, Antonio; Stanziola, Anna; Sanduzzi, Alessandro; Vatrella, Alessandro; D'Amato, Maria

    2016-01-01

    A body of evidence suggests that major changes involving the atmosphere and the climate, including global warming induced by anthropogenic factors, have impact on the biosphere and human environment. Studies on the effects of climate change on respiratory allergy are still lacking and current knowledge is provided by epidemiological and experimental studies on the relationship between allergic respiratory diseases, asthma and environmental factors, such as meteorological variables, airborne allergens, and air pollution. Urbanization with its high levels of vehicle emissions, and a westernized lifestyle are linked to the rising frequency of respiratory allergic diseases and bronchial asthma observed over recent decades in most industrialized countries. However, it is not easy to evaluate the impact of climate changes and air pollution on the prevalence of asthma in the general population and on the timing of asthma exacerbations, although the global rise in asthma prevalence and severity could also be an effect of air pollution and climate change. Since airborne allergens and air pollutants are frequently increased contemporaneously in the atmosphere, an enhanced IgE-mediated response to aeroallergens and enhanced airway inflammation could account for the increasing frequency of respiratory allergy and asthma in atopic subjects in the last 5 decades. Pollen allergy is frequently used to study the relationship between air pollution and respiratory allergic diseases, such as rhinitis and bronchial asthma. Epidemiologic studies have demonstrated that urbanization, high levels of vehicle emissions, and westernized lifestyle are correlated with an increased frequency of respiratory allergy prevalently in people who live in urban areas in comparison with people living in rural areas. Climatic factors (temperature, wind speed, humidity, thunderstorms, etc.) can affect both components (biological and chemical) of this interaction. PMID:27334776

  19. Climate Change and Air Pollution: Effects on Respiratory Allergy.

    PubMed

    D'Amato, Gennaro; Pawankar, Ruby; Vitale, Carolina; Lanza, Maurizia; Molino, Antonio; Stanziola, Anna; Sanduzzi, Alessandro; Vatrella, Alessandro; D'Amato, Maria

    2016-09-01

    A body of evidence suggests that major changes involving the atmosphere and the climate, including global warming induced by anthropogenic factors, have impact on the biosphere and human environment. Studies on the effects of climate change on respiratory allergy are still lacking and current knowledge is provided by epidemiological and experimental studies on the relationship between allergic respiratory diseases, asthma and environmental factors, such as meteorological variables, airborne allergens, and air pollution. Urbanization with its high levels of vehicle emissions, and a westernized lifestyle are linked to the rising frequency of respiratory allergic diseases and bronchial asthma observed over recent decades in most industrialized countries. However, it is not easy to evaluate the impact of climate changes and air pollution on the prevalence of asthma in the general population and on the timing of asthma exacerbations, although the global rise in asthma prevalence and severity could also be an effect of air pollution and climate change. Since airborne allergens and air pollutants are frequently increased contemporaneously in the atmosphere, an enhanced IgE-mediated response to aeroallergens and enhanced airway inflammation could account for the increasing frequency of respiratory allergy and asthma in atopic subjects in the last 5 decades. Pollen allergy is frequently used to study the relationship between air pollution and respiratory allergic diseases, such as rhinitis and bronchial asthma. Epidemiologic studies have demonstrated that urbanization, high levels of vehicle emissions, and westernized lifestyle are correlated with an increased frequency of respiratory allergy prevalently in people who live in urban areas in comparison with people living in rural areas. Climatic factors (temperature, wind speed, humidity, thunderstorms, etc.) can affect both components (biological and chemical) of this interaction. PMID:27334776

  20. Air pollution modeling and its application III

    SciTech Connect

    De Wispelaere, C.

    1984-01-01

    This book focuses on the Lagrangian modeling of air pollution. Modeling cooling tower and power plant plumes, modeling the dispersion of heavy gases, remote sensing as a tool for air pollution modeling, dispersion modeling including photochemistry, and the evaluation of model performances in practical applications are discussed. Specific topics considered include dispersion in the convective boundary layer, the application of personal computers to Lagrangian modeling, the dynamic interaction of cooling tower and stack plumes, the diffusion of heavy gases, correlation spectrometry as a tool for mesoscale air pollution modeling, Doppler acoustic sounding, tetroon flights, photochemical air quality simulation modeling, acid deposition of photochemical oxidation products, atmospheric diffusion modeling, applications of an integral plume rise model, and the estimation of diffuse hydrocarbon leakages from petrochemical factories. This volume constitutes the proceedings of the Thirteenth International Technical Meeting on Air Pollution Modeling and Its Application held in France in 1982.

  1. RESEARCH AREA -- ARTIFICIAL INTELLIGENCE CONTROL (AIR POLLUTION TECHNOLOGY BRANCH, AIR POLLUTION PREVENTION AND CONTROL DIVISION, NRMRL)

    EPA Science Inventory

    The Air Pollution Technology Branch (APTB) of NRMRL's Air Pollution Prevention and Control Division in Research Triangle Park, NC, has conducted several research projects for evaluating the use of artificial intelligence (AI) to improve the control of pollution control systems an...

  2. A semi-automated system for quantifying the oxidative potential of ambient particles in aqueous extracts using the dithiothreitol (DTT) assay: results from the Southeastern Center for Air Pollution and Epidemiology (SCAPE)

    NASA Astrophysics Data System (ADS)

    Fang, T.; Verma, V.; Guo, H.; King, L. E.; Edgerton, E. S.; Weber, R. J.

    2015-01-01

    A variety of methods are used to measure the capability of particulate matter (PM) to catalytically generate reactive oxygen species (ROS) in vivo, also defined as the aerosol oxidative potential. A widely used measure of aerosol oxidative potential is the dithiothreitol (DTT) assay, which monitors the depletion of DTT (a surrogate for cellular antioxidants) as catalyzed by the redox-active species in PM. However, a major constraint in the routine use of the DTT assay for integrating it with large-scale health studies is its labor-intensive and time-consuming protocol. To specifically address this concern, we have developed a semi-automated system for quantifying the oxidative potential of aerosol liquid extracts using the DTT assay. The system, capable of unattended analysis at one sample per hour, has a high analytical precision (coefficient of variation of 15% for positive control, 4% for ambient samples) and reasonably low limit of detection (0.31 nmol min-1). Comparison of the automated approach with the manual method conducted on ambient samples yielded good agreement (slope = 1.08 ± 0.12, r2 = 0.92, N = 9). The system was utilized for the Southeastern Center for Air Pollution & Epidemiology (SCAPE) to generate an extensive data set on DTT activity of ambient particles collected from contrasting environments (urban, roadside, and rural) in the southeastern US. We find that water-soluble PM2.5 DTT activity on a per-air-volume basis was spatially uniform and often well correlated with PM2.5 mass (r = 0.49 to 0.88), suggesting regional sources contributing to the PM oxidative potential in the southeastern US. The correlation may also suggest a mechanistic explanation (oxidative stress) for observed PM2.5 mass-health associations. The heterogeneity in the intrinsic DTT activity (per-PM-mass basis) across seasons indicates variability in the DTT activity associated with aerosols from sources that vary with season. Although developed for the DTT assay, the

  3. EXPERIMENTAL APPROACHES TO INVESTIGATE THE INTERACTION OF AIR POLLUTANTS AND LUNG DISEASE

    EPA Science Inventory

    Epidemiological studies of smokers and other people exposed to high levels of air pollutants have demonstrated that these individuals suffer from more frequent and severe respiratory infections. Studies in animals have also shown that a wide range of airborne pollutants includin...

  4. Air pollutant penetration through airflow leaks into buildings

    SciTech Connect

    Liu, De-Ling

    2002-09-01

    The penetration of ambient air pollutants into the indoor environment is of concern owing to several factors: (1) epidemiological studies have shown a strong association between ambient fine particulate pollution and elevated risk of human mortality; (2) people spend most of their time in indoor environments; and (3) most information about air pollutant concentration is only available from ambient routine monitoring networks. A good understanding of ambient air pollutant transport from source to receptor requires knowledge about pollutant penetration across building envelopes. Therefore, it is essential to gain insight into particle penetration in infiltrating air and the factors that affect it in order to assess human exposure more accurately, and to further prevent adverse human health effects from ambient particulate pollution. In this dissertation, the understanding of air pollutant infiltration across leaks in the building envelope was advanced by performing modeling predictions as well as experimental investigations. The modeling analyses quantified the extent of airborne particle and reactive gas (e.g., ozone) penetration through building cracks and wall cavities using engineering analysis that incorporates existing information on building leakage characteristics, knowledge of pollutant transport processes, as well as pollutant-surface interactions. Particle penetration is primarily governed by particle diameter and by the smallest dimension of the building cracks. Particles of 0.1-1 {micro}m are predicted to have the highest penetration efficiency, nearly unity for crack heights of 0.25 mm or higher, assuming a pressure differential of 4 Pa or greater and a flow path length of 3 cm or less. Supermicron and ultrafine particles (less than 0.1 {micro}m) are readily deposited on crack surfaces by means of gravitational settling and Brownian diffusion, respectively. The fraction of ozone penetration through building leaks could vary widely, depending

  5. Health effects of outdoor air pollution

    PubMed Central

    Abelsohn, Alan; Stieb, Dave M.

    2011-01-01

    Abstract Objective To inform family physicians about the health effects of air pollution and to provide an approach to counseling vulnerable patients in order to reduce exposure. Sources of information MEDLINE was searched using terms relevant to air pollution and its adverse effects. We reviewed English-language articles published from January 2008 to December 2009. Most studies provided level II evidence. Main message Outdoor air pollution causes substantial morbidity and mortality in Canada. It can affect both the respiratory system (exacerbating asthma and chronic obstructive pulmonary disease) and the cardiovascular system (triggering arrhythmias, cardiac failure, and stroke). The Air Quality Health Index (AQHI) is a new communication tool developed by Health Canada and Environment Canada that indicates the level of health risk from air pollution on a scale of 1 to 10. The AQHI is widely reported in the media, and the tool might be of use to family physicians in counseling high-risk patients (such as those with asthma, chronic obstructive pulmonary disease, or cardiac failure) to reduce exposure to outdoor air pollution. Conclusion Family physicians can use the AQHI and its health messages to teach patients with asthma and other high-risk patients how to reduce health risks from air pollution. PMID:21841106

  6. GIS implementation in air pollution analysis

    SciTech Connect

    Chaaban, F.G.

    1998-07-01

    Air quality modeling and simulation is an indispensable tool used in different environmental studies that attempt to estimate air pollution levels caused by existing or planned combustion processes, to evaluate proposed emission reduction technologies, to select sites for new emission sources, and accordingly to establish emission control strategies in different energy conversion sectors. Modeling techniques, based on established mathematical formulation, are widely used for simulating air pollution caused mainly by the transportation and electric power sectors. Geographic information systems, GIS, link spatial information to alphanumeric information thus developing geographically referenced database. GIS systems have already been incorporated successfully into several fields in the energy sector and are proven to be a very efficient and robust tool for relevant analysis. In the environmental studies, GIS can answer many questions related to air pollution such as pollution sources as well as identification of regions in which the concentration may exceed limits set by local and international standards. The work presented in this paper is aimed at integrating GIS into air pollution analysis. The main objective is to estimate, using advanced graphical illustrations, the concentration levels of different types of air effluents emitted from point, line, or area sources. The integrated package is then used to examine the influence of various mitigation strategies on the air pollutants levels, and hence to evaluate the effectiveness of these strategies. The paper is concluded by case studies from the transportation and power sectors.

  7. HAZARDOUS AIR POLLUTANTS: DRY-DEPOSITION PHENOMENA

    EPA Science Inventory

    Dry-deposition rates were evaluated for two hazardous organic air pollutants, nitrobenzene and perchloroethylene, to determine their potential for removal from the atmosphere to three building material surfaces, cement, tar paper, and vinyl asbestos tile. Dry-deposition experimen...

  8. ALTITUDE AS A FACTOR IN AIR POLLUTION

    EPA Science Inventory

    Air pollution is affected by change in altitude. Cities with surface elevations above 1500 meters have atmospheric pressures which are approximately fifteen percent (15%) below pressures at sea level. Consequently, mobile sources designed to operate at pressures of one atmosphere...

  9. AIR POLLUTION, OXIDATIVE STRESS AND NEUROTOXICITY.

    EPA Science Inventory

    Increased incidents of classic and variant forms of neurodegenerative diseases suggest that environmental chemicals and susceptibility factors (e.g., genetics, diseased states, obesity, etc.) may be contributory. Particulate matter (PM) is a type of air pollution that is associat...

  10. India takes steps to curb air pollution.

    PubMed

    2016-07-01

    India's air pollution problem needs to be tackled systematically, taking an all-of-government approach, to reduce the huge burden of associated ill-health. Patralekha Chatterjee reports. PMID:27429486