11. Photocopy of photograph (original located in Photograph's Office, Hawthorne ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. Photocopy of photograph (original located in Photograph's Office, Hawthorne Army Ammunition Plant, Hawthorne, Nevada). View of gymnasium, photograph no. 20107-28. - Hawthorne Naval Ammunition Depot, Gymnasium, North Main Avenue, Industrial Area, Hawthorne Army Ammunition Plant, Hawthorne, Mineral County, NV

12. Photocopy of photograph (original located in Photograph's Office, Hawthorne ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

12. Photocopy of photograph (original located in Photograph's Office, Hawthorne Army Ammunition Plant, Hawthorne, Nevada). View of swimming pool, photograph no. 20107-27. - Hawthorne Naval Ammunition Depot, Gymnasium, North Main Avenue, Industrial Area, Hawthorne Army Ammunition Plant, Hawthorne, Mineral County, NV

Hawthorn extract for treating chronic heart failure.

PubMed

Pittler, M H; Guo, R; Ernst, E

2008-01-23

Hawthorn extract is advocated as an oral treatment option for chronic heart failure. Also, the German Commission E approved the use of extracts of hawthorn leaf with flower in patients suffering from heart failure graded stage II according to the New York Heart Association. To assess the benefits and harms as reported in double-blind randomised clinical trials of hawthorn extract compared with placebo for treating patients with chronic heart failure. We searched CENTRAL on The Cochrane Library (issue 2, 2006), MEDLINE (1951 to June 2006), EMBASE (1974 to June 2006), CINAHL (1982 to June 2006) and AMED (1985 to June 2006). Experts and manufacturers were contacted. Language restrictions were not imposed. To be included, studies were required to state that they were randomised, double-blind, and placebo controlled, and used hawthorn leaf and flower extract monopreparations. Two reviewers independently performed the selection of studies, data extraction, and assessment of methodological quality. Data were entered into RevMan 4.2 software. Results from continuous data were reported as weighted mean difference (WMD) with 95% confidence interval (CI). Where data were suitable for combining, pooled results were calculated. Fourteen trials met all inclusion criteria and were included in this review. In most of the studies, hawthorn was used as an adjunct to conventional treatment. Ten trials including 855 patients with chronic heart failure (New York Heart Association classes I to III) provided data that were suitable for meta-analysis. For the physiologic outcome of maximal workload, treatment with hawthorn extract was more beneficial than placebo (WMD (Watt) 5.35, 95% CI 0.71 to 10.00, P < 0.02, n = 380). Exercise tolerance were significantly increased by hawthorn extract (WMD (Watt x min) 122.76, 95% CI 32.74 to 212.78, n = 98). The pressure-heart rate product, an index of cardiac oxygen consumption, also showed a beneficial decrease with hawthorn treatment (WMD (mm

A "H--ll-Fired Story": Hawthorne's Rhetoric of Rumor.

ERIC Educational Resources Information Center

Harshbarger, Scott

1994-01-01

Considers Nathaniel Hawthorne's literary technique of providing various, often conflicting, accounts of a narrative scene or event. Analyzes Hawthorne's rhetoric of rumor as featured in "The Scarlet Letter." Shows how Hawthorne tried to translate the dynamics of interpersonal communication into print in this novel. (HB)

75 FR 33681 - Amendment of Class D and E Airspace; Victorville, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-15

...) operations at Southern California Logistics Airport, allowing aircraft operations outside Class D airspace at... surface to and including 4,500 feet MSL within a 6-mile radius of Southern California Logistics Airport... of Southern California Logistics Airport in Class D and E airspace, and changes the airport name from...

Genetic diversity analysis of fruit characteristics of hawthorn germplasm.

PubMed

Su, K; Guo, Y S; Wang, G; Zhao, Y H; Dong, W X

2015-12-07

One hundred and six accessions of hawthorn intraspecific resources, from the National Germplasm Repository at Shenyang, were subjected to genetic diversity and principal component analysis based on evaluation data of 15 fruit traits. Results showed that the genetic diversity of hawthorn fruit traits varied. Among the 15 traits, the fruit shape variable coefficient had the most obvious evaluation, followed by fruit surface state, dot color, taste, weight of single fruit, sepal posture, peduncle form, and metula traits. These are the primary traits by which hawthorn could be classified in the future. The principal component demonstrated that these traits are the most influential factors of hawthorn fruit characteristics.

The Hawthorne effect and energy awareness

PubMed Central

Schwartz, Daniel; Fischhoff, Baruch; Krishnamurti, Tamar; Sowell, Fallaw

2013-01-01

The feeling of being observed or merely participating in an experiment can affect individuals’ behavior. Referred to as the Hawthorne effect, this inconsistently observed phenomenon can both provide insight into individuals' behavior and confound the interpretation of experimental manipulations. Here, we pursue both topics in examining how the Hawthorne effect emerges in a large field experiment focused on residential consumers’ electricity use. These consumers received five postcards notifying, and then reminding, them of their participation in a study of household electricity use. We found evidence for a Hawthorne (study participation) effect, seen in a reduction of their electricity use—even though they received no information, instruction, or incentives to change. Responses to a follow-up survey suggested that the effect reflected heightened awareness of energy consumption. Consistent with that interpretation, the treatment effect vanished when the intervention ended. PMID:24003110

Hypoglycemic effect of hawthorn in type II diabetes mellitus rat model.

PubMed

Aierken, Aili; Buchholz, Tina; Chen, Chen; Zhang, Xiaoying; Melzig, Matthias F

2017-10-01

Hawthorn is a popular herb in many different traditional medicine systems, including traditional Chinese medicine, where it has long been used for the treatment of hyperglycemia. However, most of its varied biological activities remain unexplored. This study investigated the hypoglycemic effect of hawthorn extracts in type II diabetic (T2DM) rat model. A total of 54 rats were randomly divided into six groups: normal control group; type II diabetic model group (T2DM; these rats were induced by high-fat diet and streptozotocin); high, middle and low concentrations of hawthorn treatment (HT H , HT M and HT L T2DM rats were given hawthorn extract at a dose of 50, 100 and 200 mg kg -1 body weight, respectively); and positive control group (orlistat 40 mg kg -1 body weight). Triglyceride and total cholesterol serum levels were lower in the hawthorn extract-treated groups than in the T2DM control group (P < 0.01). Furthermore, hawthorn extracts decreased blood glucose level and increased plasma insulin release from pancreas. Positive effects of hawthorn against streptozotocin-induced T2DM were demonstrated. This study suggests that hawthorn extract represents a useful agent for the prevention or treatment of T2DM. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

Interference of hawthorn on serum digoxin measurements by immunoassays and pharmacodynamic interaction with digoxin.

PubMed

Dasgupta, Amitava; Kidd, Laura; Poindexter, Brian J; Bick, Roger J

2010-08-01

Hawthorn is an herb indicated for treating cardiac illness. Because a patient taking digoxin may also take hawthorn, we investigated potential interference of hawthorn in serum digoxin measurements using immunoassays as well as pharmacodynamic interaction between hawthorn and digoxin. Hawthorn contains alkaloids that are structurally similar to digoxin and may interfere with serum digoxin measurement using immunoassays. In addition, hawthorn has cardioactive properties similar to digoxin. To study potential pharmacodynamic interaction between hawthorn and digoxin. The effects of hawthorn extract on serum digoxin measurements using Digoxin III (Abbott Laboratories, Abbott Park, Illinois) and the Tina-Quant digoxin assay (Roche Diagnostics, Indianapolis, Indiana) were investigated using 2 different brands of extract. To study the pharmacodynamic interaction between hawthorn and digoxin, we used an isolated adult rat cardiomyocyte system, measuring calcium transients by real-time fluorescence spectrophotometry. Hawthorn interfered only with the Digoxin III immunoassay but had no effect on the Tina-Quant assay. Both hawthorn extracts increased intracellular calcium levels, but the lack of additive response with digoxin suggests both may bind to the same site of Na, K adenosine triphosphatase. Because of interference of hawthorn with a digoxin immunoassay and pharmacodynamic interaction with digoxin, a patient receiving digoxin should avoid hawthorn.

Hawthorn (Crataegus spp.) in the treatment of cardiovascular disease

PubMed Central

Tassell, Mary C.; Kingston, Rosari; Gilroy, Deirdre; Lehane, Mary; Furey, Ambrose

2010-01-01

The medicinal properties of hawthorn (Crataegus spp., a genus comprising approximately 300 species) have been utilized by many cultures for a variety of therapeutic purposes for many centuries. In the Western world cardiovascular disease (CVD) has become one of the single most significant causes of premature death. Echoing this situation, more recent research into the therapeutic benefits of hawthorn preparations has focused primarily upon its cardiovascular effects. This review covers research into the various mechanisms of action proposed for Crataegus preparations, clinical trials involving Crataegus preparations, and the herb's safety profile. Clinical trials reviewed have been inconsistent in terms of criteria used (sample size, preparation, dosage, etc) but have been largely consistent with regard to positive outcomes. An investigation into data available to date regarding hawthorn preparations and herb/drug interactions reveals that theoretical adverse interactions have not been experienced in practice. Further, adverse reactions relating to the use of hawthorn preparations are infrequent and mild, even at higher dosage ranges. A recent retrospective study by Zick et al. has suggested a negative outcome for the long-term use of hawthorn in the prognosis of heart failure. These findings are examined in this paper. Although further research is needed in certain areas, current research to date suggests that hawthorn may potentially represent a safe, effective, nontoxic agent in the treatment of CVD and ischemic heart disease (IHD). PMID:22228939

Hawthorn (Crataegus spp.) in the treatment of cardiovascular disease.

PubMed

Tassell, Mary C; Kingston, Rosari; Gilroy, Deirdre; Lehane, Mary; Furey, Ambrose

2010-01-01

The medicinal properties of hawthorn (Crataegus spp., a genus comprising approximately 300 species) have been utilized by many cultures for a variety of therapeutic purposes for many centuries. In the Western world cardiovascular disease (CVD) has become one of the single most significant causes of premature death. Echoing this situation, more recent research into the therapeutic benefits of hawthorn preparations has focused primarily upon its cardiovascular effects. This review covers research into the various mechanisms of action proposed for Crataegus preparations, clinical trials involving Crataegus preparations, and the herb's safety profile.Clinical trials reviewed have been inconsistent in terms of criteria used (sample size, preparation, dosage, etc) but have been largely consistent with regard to positive outcomes. An investigation into data available to date regarding hawthorn preparations and herb/drug interactions reveals that theoretical adverse interactions have not been experienced in practice. Further, adverse reactions relating to the use of hawthorn preparations are infrequent and mild, even at higher dosage ranges. A recent retrospective study by Zick et al. has suggested a negative outcome for the long-term use of hawthorn in the prognosis of heart failure. These findings are examined in this paper.Although further research is needed in certain areas, current research to date suggests that hawthorn may potentially represent a safe, effective, nontoxic agent in the treatment of CVD and ischemic heart disease (IHD).

77 FR 38475 - Amendment of Class E Airspace; Woodland, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-28

... Lind Avenue SW., Renton, WA 98057; telephone (425) 203-4537. SUPPLEMENTARY INFORMATION: History On...: Paragraph 6005 Class E airspace areas extending upward from 700 feet or more above the surface of the earth...

Intestinal absorption of hawthorn flavonoids--in vitro, in situ and in vivo correlations.

PubMed

Zuo, Zhong; Zhang, Li; Zhou, Limin; Chang, Qi; Chow, Moses

2006-11-25

Our previous studies identified hyperoside (HP), isoquercitrin (IQ) and epicatechin (EC) to be the major active flavonoid components of the hawthorn phenolic extract from hawthorn fruits demonstrating inhibitory effect on in vitro Cu(+2)-mediated low density lipoproteins oxidation. Among these three hawthorn flavonoids, EC was the only one detectable in plasma after the oral administration of hawthorn phenolic extract to rats. The present study aims to investigate the intestinal absorption mechanisms of these three hawthorn flavonoids by in vitro Caco-2 monolayer model, rat in situ intestinal perfusion model and in vivo pharmacokinetics studies in rats. In addition, in order to investigate the effect of the co-occurring components in hawthorn phenolic extract on the intestinal absorption of these three major hawthorn flavonoids, intestinal absorption transport profiles of HP, IQ and EC in forms of individual pure compound, mixture of pure compounds and hawthorn phenolic extract were studied and compared. The observations from in vitro Caco-2 monolayer model and in situ intestinal perfusion model indicated that all three studied hawthorn flavonoids have quite limited permeabilities. EC and IQ demonstrated more extensive metabolism in the rat in situ intestinal perfusion model and in vivo study than in Caco-2 monolayer model. Moreover, results from the Caco-2 monolayer model, rat in situ intestinal perfusion model as well as the in vivo pharmacokinetics studies in rats consistently showed that the co-occurring components in hawthorn phenolic extract might not have significant effect on the intestinal absorption of the three major hawthorn flavonoids studied.

Hawthorn (Crataegus monogyna Jacq.) extract exhibits atropine-sensitive activity in a cultured cardiomyocyte assay.

PubMed

Salehi, Satin; Long, Shannon R; Proteau, Philip J; Filtz, Theresa M

2009-01-01

Hawthorn (Crataegus spp.) plant extract is used as a herbal alternative medicine for the prevention and treatment of various cardiovascular diseases. Recently, it was shown that hawthorn extract preparations caused negative chronotropic effects in a cultured neonatal murine cardiomyocyte assay, independent of beta-adrenergic receptor blockade. The aim of this study was to further characterize the effect of hawthorn extract to decrease the contraction rate of cultured cardiomyocytes. To test the hypothesis that hawthorn is acting via muscarinic receptors, the effect of hawthorn extract on atrial versus ventricular cardiomyocytes in culture was evaluated. As would be expected for activation of muscarinic receptors, hawthorn extract had a greater effect in atrial cells. Atrial and/or ventricular cardiomyocytes were then treated with hawthorn extract in the presence of atropine or himbacine. Changes in the contraction rate of cultured cardiomyocytes revealed that both muscarinic antagonists significantly attenuated the negative chronotropic activity of hawthorn extract. Using quinuclidinyl benzilate, L-[benzylic-4,4'-(3)H] ([(3)H]-QNB) as a radioligand antagonist, the effect of a partially purified hawthorn extract fraction to inhibit muscarinic receptor binding was quantified. Hawthorn extract fraction 3 dose-dependently inhibited [(3)H]-QNB binding to mouse heart membranes. Taken together, these findings suggest that decreased contraction frequency by hawthorn extracts in neonatal murine cardiomyocytes may be mediated via muscarinic receptor activation.

Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) Trial

PubMed Central

Zick, Suzanna M.; Vautaw, Bonnie Motyka; Gillespie, Brenda; Aaronson, Keith D.

2009-01-01

Aims Hawthorn's efficacy when added to contemporary evidence-based heart failure therapy is unknown. We aimed to determine whether hawthorn increases submaximal exercise capacity when added to standard medical therapy. Methods and results We performed a randomized, double-blind, placebo-controlled trial in 120 ambulatory patients aged ≥18 years with New York Heart Association (NYHA) class II-III chronic heart failure. All patients received conventional medical therapy, as tolerated, and were randomized to either hawthorn 450 mg twice daily or placebo for 6 months. The primary outcome was change in 6 min walk distance at 6 months. Secondary outcomes included quality of life (QOL) measures, peak oxygen consumption, and anaerobic threshold during maximal treadmill exercise testing, NYHA classification, left ventricular ejection fraction (LVEF), neurohormones, and measures of oxidative stress and inflammation. There were no significant differences between groups in the change in 6 min walk distance (P = 0.61), or on measures of QOL, functional capacity, neurohormones, oxidative stress, or inflammation. A modest difference in LVEF favoured hawthorn (P = 0.04). There were significantly more adverse events reported in the hawthorn group (P = 0.02), although most were non-cardiac. Conclusion Hawthorn provides no symptomatic or functional benefit when given with standard medical therapy to patients with heart failure. This trial is registered in ClinicalTrials.gov ID: NCT00343902. PMID:19789403

Hawthorn Extract Randomized Blinded Chronic Heart Failure (HERB CHF) trial.

PubMed

Zick, Suzanna M; Vautaw, Bonnie Motyka; Gillespie, Brenda; Aaronson, Keith D

2009-10-01

Hawthorn's efficacy when added to contemporary evidence-based heart failure therapy is unknown. We aimed to determine whether hawthorn increases submaximal exercise capacity when added to standard medical therapy. We performed a randomized, double-blind, placebo-controlled trial in 120 ambulatory patients aged > or = 18 years with New York Heart Association (NYHA) class II-III chronic heart failure. All patients received conventional medical therapy, as tolerated, and were randomized to either hawthorn 450 mg twice daily or placebo for 6 months. The primary outcome was change in 6 min walk distance at 6 months. Secondary outcomes included quality of life (QOL) measures, peak oxygen consumption, and anaerobic threshold during maximal treadmill exercise testing, NYHA classification, left ventricular ejection fraction (LVEF), neurohormones, and measures of oxidative stress and inflammation. There were no significant differences between groups in the change in 6 min walk distance (P = 0.61), or on measures of QOL, functional capacity, neurohormones, oxidative stress, or inflammation. A modest difference in LVEF favoured hawthorn (P = 0.04). There were significantly more adverse events reported in the hawthorn group (P = 0.02), although most were non-cardiac. Hawthorn provides no symptomatic or functional benefit when given with standard medical therapy to patients with heart failure. This trial is registered in ClinicalTrials.gov ID: NCT00343902.

[Study on self-microemulsifying membrane controlled-release drop pill of hawthorn leaves flavonoids].

PubMed

Wang, Jin-Xuan; Huang, Hong-Zhang; Li, Ning; Gao, Chong-Kai

2014-03-01

To prepare the hawthorn leaves flavonoids self-microemulsifying membrane controlled-release coated drop pill, and to study its release rate in vitro and pharmacokinetics study in vivo. In order to improve the dissolution of hawthorn leaves flavonoids, self-microemulsifying technology was used to prepare the hawthorn leaves flavonoids self-microemulsion. Hawthorn leaves flavonoids self-microemulsifying drop pill was prepared with the PEG 6000. Studies were made on the in vitro release of flavonoids from hawthorn leaves self-micro-emulsifying membrane-moderated coated drop pills and the in vivo pharmacokinetic in rats. The prescription of flavonoids from hawthorn leaves self-micro-emulsifying drop pills was 0.25 g of flavonoids from hawthorn leaves, 0.25 g of iodophenyl maleimide, 0.375 g of polyethylene glycol 400, 0.375 g of cremophor RH 40 and 2 g of polyethylene glycol 6000. The optimized prescription was 4 g of ethyl cellulose 20, 0.64 g of polyethylene glycol 400, 1.8 g of diethyl phthalate, and the weight of coating materials increased by 3.5%. Flavonoids from hawthorn leaves self-micro-emulsifying membrane-moderated coated drop pills complied with the design of sustained-release in 12 h in terms of in vitro release and in vivo pharmacokinetic parameters in rats, and its bioavailability was 2.47 times of quick-release drop pills. Slightly soluble flavonoids from hawthorn leaves could be made into sustained-release preparations by the self-micro-emulsifying and coating technology.

75 FR 17406 - Hawthorn Oil Transportation; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-06

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. AC10-62-000] Hawthorn Oil Transportation; Notice of Filing March 31, 2010. Take notice that on February 12, 2010, Hawthorn Oil Transportation submitted a request for the waiver of the requirement to file the 2009 FERC Form No. 6 Annual...

Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha).

PubMed

Tankanow, Roberta; Tamer, Helen R; Streetman, Daniel S; Smith, Scott G; Welton, Janice L; Annesley, Thomas; Aaronson, Keith D; Bleske, Barry E

2003-06-01

Hawthorn, an herbal supplement, is currently being evaluated for the treatment of heart failure. The flavonoid components of hawthorn may be responsible for hawthorn's beneficial effects in the treatment of heart failure. However, these components may also affect P-glycoprotein function and cause interactions with drugs that are P-glycoprotein substrates, such as digoxin, which is also used to treat heart failure. Therefore, the purpose of this study was to determine the effect of hawthorn on digoxin pharmacokinetic parameters. A randomized, crossover trial with 8 healthy volunteers was performed evaluating digoxin 0.25 mg alone (D) for 10 days and digoxin 0.25 mg with Crataegus special extract WS 1442 (hawthorn leaves with flowers; Dr. Willmar Schwabe Pharmaceuticals) 450 mg twice daily (D + H) for 21 days. Pharmacokinetic studies were performed for 72 hours. There were no statistically significant differences in any measured pharmacokinetic parameters. The AUC0-infinity, Cmax-Cmin, Cmin, and renal clearance for the D group were 79 +/- 26 mcg.h/L, 1.4 +/- 0.7 mcg/L, 0.84 +/- 0.2 mcg/L, and 74 +/- 10 mL/min versus 73 +/- 20 mcg.h/L, 1.1 +/- 0.1 mcg/L, 0.65 +/- 0.2 mcg/L, and 81 +/- 22 mL/min for the D + H group, respectively (p > 0.05). Following 3 weeks of concomitant therapy, hawthorn did not significantly alter the pharmacokinetic parameters for digoxin. This suggests that both hawthorn and digoxin, in the doses and dosage form studied, may be coadministered safely.

Identification of host fruit volatiles from domestic apple (Malus domestica), native black hawthorn (Crataegus douglasii) and introduced ornamental hawthorn (C. monogyna) attractive to Rhagoletis pomonella flies from the western United States.

PubMed

Cha, Dong H; Yee, Wee L; Goughnour, Robert B; Sim, Sheina B; Powell, Thomas H Q; Feder, Jeffrey L; Linn, Charles E

2012-03-01

The apple maggot fly, Rhagoletis pomonella, infests apple (Malus domestica) and hawthorn species (most notably the downy hawthorn, Crataegus mollis) in the eastern USA. Evidence suggests that the fly was introduced into the western USA sometime in the last 60 years. In addition to apple, R. pomonella also infests two species of hawthorns in the western USA as major hosts: the native black hawthorn (C. douglasii) and the introduced ornamental English hawthorn, C. monogyna. Apple and downy hawthorn-origin flies in the eastern USA use volatile blends emitted from the surface of their respective ripening fruit to find and discriminate among host trees. To test whether the same is true for western flies, we used coupled gas chromatography and electroantennographic detection (GC-EAD) and developed a 7-component apple fruit blend for western apple-origin flies, an 8-component black hawthorn fruit blend for flies infesting C. douglasii, and a 9-component ornamental hawthorn blend for flies from C. monogyna. Crataegus douglasii and C. monogyna-origin flies showed similar levels of upwind directed flight to their respective natal synthetic fruit blends in flight tunnel assays compared to whole fruit adsorbent extracts, indicating that the blends contain all the behaviorally relevant fruit volatiles to induce maximal response levels. The black and ornamental hawthorn blends shared four compounds in common including 3-methylbutan-1-ol, which appears to be a key volatile for R. pomonella populations in the eastern, southern, and western USA that show a preference for fruit from different Crataegus species. However, the blends also differed from one another and from domesticated apple in several respects that make it possible that western R. pomonella flies behaviorally discriminate among fruit volatiles and form ecologically differentiated host races, as is the case for eastern apple and hawthorn flies.

Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials.

PubMed

Pittler, Max H; Schmidt, Katja; Ernst, Edzard

2003-06-01

The aim of this meta-analysis was to assess the evidence from rigorous clinical trials of the use of hawthorn extract to treat patients with chronic heart failure. We searched the literature using MEDLINE, EMBASE, the Cochrane Library, CINAHL, CISCOM, and AMED. Experts on and manufacturers of commercial preparations containing hawthorn extract were asked to contribute published and unpublished studies. There were no restrictions about the language of publication. Two reviewers independently performed the screening of studies, selection, validation, data extraction, and the assessment of methodological quality. To be included, studies were required to state that they were randomized, double-blind, and placebo controlled, and used hawthorn extract monopreparations. Thirteen trials met all inclusion criteria. In most of the studies, hawthorn was used as an adjunct to conventional treatment. Eight trials including 632 patients with chronic heart failure (New York Heart Association classes I to III) provided data that were suitable for meta-analysis. For the physiologic outcome of maximal workload, treatment with hawthorn extract was more beneficial than placebo (weighted mean difference, 7 Watt; 95% confidence interval [CI]: 3 to 11 Watt; P < 0.01; n = 310 patients). The pressure-heart rate product also showed a beneficial decrease (weighted mean difference, -20; 95% CI: -32 to -8; n = 264 patients) with hawthorn treatment. Symptoms such as dyspnea and fatigue improved significantly with hawthorn treatment as compared with placebo. Reported adverse events were infrequent, mild, and transient; they included nausea, dizziness, and cardiac and gastrointestinal complaints. In conclusion, these results suggest that there is a significant benefit from hawthorn extract as an adjunctive treatment for chronic heart failure.

Dynamic Airspace Configuration

NASA Technical Reports Server (NTRS)

Bloem, Michael J.

2014-01-01

In air traffic management systems, airspace is partitioned into regions in part to distribute the tasks associated with managing air traffic among different systems and people. These regions, as well as the systems and people allocated to each, are changed dynamically so that air traffic can be safely and efficiently managed. It is expected that new air traffic control systems will enable greater flexibility in how airspace is partitioned and how resources are allocated to airspace regions. In this talk, I will begin by providing an overview of some previous work and open questions in Dynamic Airspace Configuration research, which is concerned with how to partition airspace and assign resources to regions of airspace. For example, I will introduce airspace partitioning algorithms based on clustering, integer programming optimization, and computational geometry. I will conclude by discussing the development of a tablet-based tool that is intended to help air traffic controller supervisors configure airspace and controllers in current operations.

Triterpenic Acids Present in Hawthorn Lower Plasma Cholesterol by Inhibiting Intestinal ACAT Activity in Hamsters

PubMed Central

Lin, Yuguang; Vermeer, Mario A.; Trautwein, Elke A.

2011-01-01

Hawthorn (Crataegus pinnatifida) is an edible fruit used in traditional Chinese medicine to lower plasma lipids. This study explored lipid-lowering compounds and underlying mechanisms of action of hawthorn. Hawthorn powder extracts inhibited acylCoA:cholesterol acyltransferase (ACAT) activity in Caco-2 cells. The inhibitory activity was positively associated with triterpenic acid (i.e., oleanolic acid (OA) and ursolic acid (UA)) contents in the extracts. Cholesterol lowering effects of hawthorn and its potential additive effect in combination with plant sterol esters (PSE) were further studied in hamsters. Animals were fed a semi-synthetic diet containing 0.08% (w/w) cholesterol (control) or the same diet supplemented with (i) 0.37% hawthorn dichloromethane extract, (ii) 0.24% PSE, (iii) hawthorn dichloromethane extract (0.37%) plus PSE (0.24%) or (iv) OA/UA mixture (0.01%) for 4 weeks. Compared to the control diet, hawthorn, PSE, hawthorn plus PSE and OA/UA significantly lowered plasma non-HDL (VLDL + LDL) cholesterol concentrations by 8%, 9%, 21% and 6% and decreased hepatic cholesterol ester content by 9%, 23%, 46% and 22%, respectively. The cholesterol lowering effects of these ingredients were conversely associated with their capacities in increasing fecal neutral sterol excretion. In conclusion, OA and UA are responsible for the cholesterol lowering effect of hawthorn by inhibiting intestinal ACAT activity. In addition, hawthorn and particularly its bioactive compounds (OA and UA) enhanced the cholesterol lowering effect of plant sterols. PMID:19228775

Triterpenic Acids Present in Hawthorn Lower Plasma Cholesterol by Inhibiting Intestinal ACAT Activity in Hamsters.

PubMed

Lin, Yuguang; Vermeer, Mario A; Trautwein, Elke A

2011-01-01

Hawthorn (Crataegus pinnatifida) is an edible fruit used in traditional Chinese medicine to lower plasma lipids. This study explored lipid-lowering compounds and underlying mechanisms of action of hawthorn. Hawthorn powder extracts inhibited acylCoA:cholesterol acyltransferase (ACAT) activity in Caco-2 cells. The inhibitory activity was positively associated with triterpenic acid (i.e., oleanolic acid (OA) and ursolic acid (UA)) contents in the extracts. Cholesterol lowering effects of hawthorn and its potential additive effect in combination with plant sterol esters (PSE) were further studied in hamsters. Animals were fed a semi-synthetic diet containing 0.08% (w/w) cholesterol (control) or the same diet supplemented with (i) 0.37% hawthorn dichloromethane extract, (ii) 0.24% PSE, (iii) hawthorn dichloromethane extract (0.37%) plus PSE (0.24%) or (iv) OA/UA mixture (0.01%) for 4 weeks. Compared to the control diet, hawthorn, PSE, hawthorn plus PSE and OA/UA significantly lowered plasma non-HDL (VLDL + LDL) cholesterol concentrations by 8%, 9%, 21% and 6% and decreased hepatic cholesterol ester content by 9%, 23%, 46% and 22%, respectively. The cholesterol lowering effects of these ingredients were conversely associated with their capacities in increasing fecal neutral sterol excretion. In conclusion, OA and UA are responsible for the cholesterol lowering effect of hawthorn by inhibiting intestinal ACAT activity. In addition, hawthorn and particularly its bioactive compounds (OA and UA) enhanced the cholesterol lowering effect of plant sterols.

APPLICATION OF DRY HAWTHORN (CRATAEGUS OXYACANTHA L.) EXTRACT IN NATURAL TOPICAL FORMULATIONS.

PubMed

Stelmakiene, Ada; Ramanauskiene, Kristina; Petrikaite, Vilma; Jakstas, Valdas; Briedis, Vitalis

2016-07-01

There is a great potential for a semi-solid preparation for topical application to the skin that would use materials of natural origin not only as an active substance but also as its base. The aim of this research was to model semisolid preparations containing hawthorn extract and to determine the effect of their bases (carriers) on the release of active components from experimental dosage forms, based on the results of the in vitro studies of the bioactivity of hawthorn active components and ex vivo skin penetration studies. The active compounds of hawthorn were indentified and quantified by validated HPLC method. The antimicrobial and anti-radical activity of dry hawthorn extract were evaluated by methods in vitro. The penetration of active substances into the full undamaged human skin was evaluated by method ex vivo. Natural topical composition was chosen according to the results of release of active compounds. Release experiments were performed with modified Franz type diffusion cells. B.ceieus was the most sensitive bacteria for the hawthorn extract. Extract showed antiradical activity, however the penetration was limited. Only traces of hyperoside and isoquercitrin were founded in epidermis. Protective topical preparation with shea butter released 41.4-42.4% of active substances. Four major compounds of dry hawthorn extract were identified. The research showed that extract had antimicrobial and antiradical activity, however compounds of hawthorn stay on the surface of the undamaged human skin. Topical preparation containing beeswax did not release active compounds. Beeswax was identified as suspending agent. Topical preparations released active compounds when shea butter was used instead of beeswax.

[Detection of Hawthorn Fruit Defects Using Hyperspectral Imaging].

PubMed

Liu, De-hua; Zhang, Shu-juan; Wang, Bin; Yu, Ke-qiang; Zhao, Yan-ru; He, Yong

2015-11-01

Hyperspectral imaging technology covered the range of 380-1000 nm was employed to detect defects (bruise and insect damage) of hawthorn fruit. A total of 134 samples were collected, which included damage fruit of 46, pest fruit of 30, injure and pest fruit of 10 and intact fruit of 48. Because calyx · s⁻¹ tem-end and bruise/insect damage regions offered a similar appearance characteristic in RGB images, which could produce easily confusion between them. Hence, five types of defects including bruise, insect damage, sound, calyx, and stem-end were collected from 230 hawthorn fruits. After acquiring hyperspectral images of hawthorn fruits, the spectral data were extracted from region of interest (ROI). Then, several pretreatment methods of standard normalized variate (SNV), savitzky golay (SG), median filter (MF) and multiplicative scatter correction (MSC) were used and partial least squares method(PLS) model was carried out to obtain the better performance. Accordingly to their results, SNV pretreatment methods assessed by PLS was viewed as best pretreatment method. Lastly, SNV was chosen as the pretreatment method. Spectral features of five different regions were combined with Regression coefficients(RCs) of partial least squares-discriminant analysis (PLS-DA) model was used to identify the important wavelengths and ten wavebands at 483, 563, 645, 671, 686, 722, 777, 819, 837 and 942 nm were selected from all of the wavebands. Using Kennard-Stone algorithm, all kinds of samples were randomly divided into training set (173) and test set (57) according to the proportion of 3:1. And then, least squares-support vector machine (LS-SVM) discriminate model was established by using the selected wavebands. The results showed that the discriminate accuracy of the method was 91.23%. In the other hand, images at ten important wavebands were executed to Principal component analysis (PCA). Using "Sobel" operator and region growing algrorithm "Regiongrow", the edge and defect

76 FR 46212 - Proposed Modification of Class E Airspace; Blythe, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-02

... procedures at Blythe Airport. The FAA is proposing this action to enhance the safety and management of... be submitted in triplicate to the Docket Management System (see ADDRESSES section for address and... controlled airspace is necessary to accommodate aircraft using the RNAV (GPS) standard instrument approach...

78 FR 78296 - Proposed Establishment of Class E Airspace; Needles, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-26

... Instrument Flight Rules (IFR) aircraft under control of Los Angeles Air Route Traffic Control Center (ARTCC... be changed in light of comments received. All comments submitted will be available for examination in... http://www.faa.gov/airports_airtraffic/air_traffic/publications/airspace_amendments/ . You may review...

Evaluation of hawthorn extract on immunomodulatory biomarkers in a pressure overload model of heart failure.

PubMed

Bleske, Barry E; Zineh, Issam; Hwang, Hyun Seok; Welder, Gregory J; Ghannam, Michael M J; Boluyt, Marvin O

2007-12-01

Hawthorn extract (Crataegeus sp.) a botanical complementary and alternative medicine is often used to treat heart failure. The mechanism(s) by which hawthorn extract may treat heart failure is unknown but may include, theoretically, immunological effects. Therefore, the purpose of this study is to determine the effect of hawthorn extract on the immunomodulatory response in a pressure overload model of heart failure. A total of 62 male Sprague-Dawley rats were randomized to either aortic constriction + vehicle (AC; n=15), aortic constriction + hawthorn 1.3 mg/kg (HL, n=17), aortic constriction + hawthorn 13 mg/kg (HM, n=15), or aortic constriction + hawthorn 130 mg/kg (HH, n=15). Six months after surgical procedure animals were sacrificed and plasma samples obtained for the measurement of the following immunomodulatory markers: interleukin (IL) IL-1ss, IL-2, IL-6, IL-10; and leptin. The mortality rate following 6 months of aortic constriction was 40% in the AC group compared to 41%, 60%, and 53% for the HL, HM, and HH groups respectively (P>0.05 compared to AC). Aortic constriction produced a similar increase in the left ventricle/body weight ratio for all groups. Hawthorn extract had no effect on the immunomodulatory markers measured in this study, although there appeared to be a trend suggesting suppression of IL-2 plasma concentrations. In this animal model of heart failure, hawthorn extract failed to significantly affect the immunomodulatory response characterized after 6 months of pressure overload at a time when approximately 50% mortality was exhibited. Mechanisms other than immunological may better define hawthorn's effect in treating heart failure.

Immunomodulatory effect of Hawthorn extract in an experimental stroke model.

PubMed

Elango, Chinnasamy; Devaraj, Sivasithambaram Niranjali

2010-12-30

Recently, we reported a neuroprotective effect for Hawthorn (Crataegus oxyacantha) ethanolic extract in middle cerebral artery occlusion-(MCAO) induced stroke in rats. The present study sheds more light on the extract's mechanism of neuroprotection, especially its immunomodulatory effect. After 15 days of treatment with Hawthorn extract [100 mg/kg, pretreatment (oral)], male Sprague Dawley rats underwent transient MCAO for 75 mins followed by reperfusion (either 3 or 24 hrs). We measured pro-inflammatory cytokines (IL-1β, TNF-α, IL-6), ICAM-1, IL-10 and pSTAT-3 expression in the brain by appropriate methods. We also looked at the cytotoxic T cell sub-population among leukocytes (FACS) and inflammatory cell activation and recruitment in brain (using a myeloperoxidase activity assay) after ischemia and reperfusion (I/R). Apoptosis (TUNEL), and Bcl-xL- and Foxp3- (T(reg) marker) positive cells in the ipsilateral hemisphere of the brain were analyzed separately using immunofluorescence. Our results indicate that occlusion followed by 3 hrs of reperfusion increased pro-inflammatory cytokine and ICAM-1 gene expressions in the ipsilateral hemisphere, and that Hawthorn pre-treatment significantly (p ≤ 0.01) lowered these levels. Furthermore, such pre-treatment was able to increase IL-10 levels and Foxp3-positive cells in brain after 24 hrs of reperfusion. The increase in cytotoxic T cell population in vehicle rats after 24 hrs of reperfusion was decreased by at least 40% with Hawthorn pretreatment. In addition, there was a decrease in inflammatory cell activation and infiltration in pretreated brain. Hawthorn pretreatment elevated pSTAT-3 levels in brain after I/R. We also observed an increase in Bcl-xL-positive cells, which in turn may have influenced the reduction in TUNEL-positive cells compared to vehicle-treated brain. In summary, Hawthorn extract helped alleviate pro-inflammatory immune responses associated with I/R-induced injury, boosted IL-10 levels, and

Immunomodulatory effect of Hawthorn extract in an experimental stroke model

PubMed Central

2010-01-01

Background Recently, we reported a neuroprotective effect for Hawthorn (Crataegus oxyacantha) ethanolic extract in middle cerebral artery occlusion-(MCAO) induced stroke in rats. The present study sheds more light on the extract's mechanism of neuroprotection, especially its immunomodulatory effect. Methods After 15 days of treatment with Hawthorn extract [100 mg/kg, pretreatment (oral)], male Sprague Dawley rats underwent transient MCAO for 75 mins followed by reperfusion (either 3 or 24 hrs). We measured pro-inflammatory cytokines (IL-1β, TNF-α, IL-6), ICAM-1, IL-10 and pSTAT-3 expression in the brain by appropriate methods. We also looked at the cytotoxic T cell sub-population among leukocytes (FACS) and inflammatory cell activation and recruitment in brain (using a myeloperoxidase activity assay) after ischemia and reperfusion (I/R). Apoptosis (TUNEL), and Bcl-xL- and Foxp3- (Treg marker) positive cells in the ipsilateral hemisphere of the brain were analyzed separately using immunofluorescence. Results Our results indicate that occlusion followed by 3 hrs of reperfusion increased pro-inflammatory cytokine and ICAM-1 gene expressions in the ipsilateral hemisphere, and that Hawthorn pre-treatment significantly (p ≤ 0.01) lowered these levels. Furthermore, such pre-treatment was able to increase IL-10 levels and Foxp3-positive cells in brain after 24 hrs of reperfusion. The increase in cytotoxic T cell population in vehicle rats after 24 hrs of reperfusion was decreased by at least 40% with Hawthorn pretreatment. In addition, there was a decrease in inflammatory cell activation and infiltration in pretreated brain. Hawthorn pretreatment elevated pSTAT-3 levels in brain after I/R. We also observed an increase in Bcl-xL-positive cells, which in turn may have influenced the reduction in TUNEL-positive cells compared to vehicle-treated brain. Conclusions In summary, Hawthorn extract helped alleviate pro-inflammatory immune responses associated with I

Beyond a good story: from Hawthorne Effect to reactivity in health professions education research.

PubMed

Paradis, Elise; Sutkin, Gary

2017-01-01

Observational research is increasingly being used in health professions education (HPE) research, yet it is often criticised for being prone to observer effects (also known as the Hawthorne Effect), defined as a research participant's altered behaviour in response to being observed. This article explores this concern. First, this article briefly reviews the initial Hawthorne studies and the original formulation of the Hawthorne Effect, before turning to contemporary studies of the Hawthorne Effect in HPE and beyond. Second, using data from two observational studies (in the operating theatre and in the intensive care unit), this article investigates the Hawthorne Effect in HPE. Evidence of a Hawthorne Effect is scant, and amounts to little more than a good story. This is surprising given the foundational nature of the Hawthorne Studies in the social sciences and the prevalence of our concern with observer effects in HPE research. Moreover, the multiple and inconsistent uses of the Hawthorne Effect have left researchers without a coherent and helpful understanding of research participants' responses to observation. The authors' HPE research illustrates the complexity of observer effects in HPE, suggests that significant alteration of behaviour is unlikely in many research contexts, and shows how sustained contact with participants over time improves the quality of data collection. This article thus concludes with three recommendations: that researchers, editors and reviewers in the HPE community use the phrase 'participant reactivity' when considering the participant, observer and research question triad; that researchers invest in interpersonal relationships at their study site to mitigate the effects of altered behaviour; and that researchers use theory to make sense of participants' altered behaviour and use it as a window into the social world. The term 'participant reactivity' better reflects current scientific understandings of the research process and

Antioxidant capacity of polyphenolic extracts from leaves of Crataegus laevigata and Crataegus monogyna (Hawthorn) subjected to drought and cold stress.

PubMed

Kirakosyan, Ara; Seymour, Elisabeth; Kaufman, Peter B; Warber, Sara; Bolling, Steven; Chang, Soo Chul

2003-07-02

Crataegus laevigata and Crataegus monogyna (hawthorn) were subjected to drought and cold stress treatments, and polyphenolic extracts from control and stress-treated plants were assayed for antioxidant capacities using a modified version of the Total Antioxidant Status Assay (Randox, San Francisco, CA). In addition, these plants were analyzed for levels of flavanol-type substance [(-)-epicatechin] and flavonoid (vitexin 2' '-O-rhamnoside, acetylvitexin 2' '-O-rhamnoside, and hyperoside) constituents that are important metabolites in hawthorn herbal preparations used to treat patients with heart disease. Drought and cold stress treatments caused increases in levels of (-)-epicatechin and hyperoside in both Crataegus species. Such treatments also enhanced the antioxidant capacity of the extracts. The results from this study thus indicate that these kinds of stress treatments can enhance the levels of important secondary metabolites and their total antioxidant capacities in leaves of Crataegus.

Effect of a hawthorn extract on contraction and energy turnover of isolated rat cardiomyocytes.

PubMed

Pöpping, S; Rose, H; Ionescu, I; Fischer, Y; Kammermeier, H

1995-11-01

The hawthorn extract LI 132 (crataegus), prepared from leaves and flowers, and standardised to 2.2% flavonoids, was investigated with respect to its effect on (1) the contraction, (2) the energy-turnover and (3) the apparent refractory period (t(ref)) of isolated cardiac myocytes from adult rats. (1) The contractile behaviour of attached myocytes was analyzed by an image processing system. (2) The energy turnover was calculated from the decrease in oxygen content in the myocyte suspension, brought about by cellular respiration. It was differentiated between energy turnover related to cell shortening and that required for ionic transport processes by application of the contraction-inhibiting agent 2,3-butanedione monoxime. (3) The apparent refractory period (t(ref)) was evaluated by pacing the myocytes with increasing stimulation rates and determining the frequency at which failure of single contractions occurred. For these purposes, the myocytes were incubated in a stimulation chamber, which is part of a computer-assisted system allowing to simultaneously evaluate the mechanics and energetics of electrically induced contraction. Within a range of 30-180 microg/ml, the hawthorn extract exhibited a positive inotropic effect on the contraction amplitude accompanied by a moderate increase of energy turnover both for mechanical and ionic processes. In comparison with other positive inotropic interventions, such as application of the beta-adrenergic agonist isoprenaline, or of the cardiac glycoside ouabain (g-strophantin), or elevation of the extracellular Ca++-concentration, the effects of the hawthorn extract were significantly more economical with respect to the energetics of the myocytes. Furthermore the extract prolonged the apparent refractory period in the presence and the absence of isoprenaline, which be indicative for an antiarrhythmic potential.

Protective effect of hawthorn extract against genotoxicity induced by methyl methanesulfonate in human lymphocytes.

PubMed

Hosseinimehr, Seyed Jalal; Azadbakht, Mohammad; Tanha, Mohammad; Mahmodzadeh, Aziz; Mohammadifar, Sohila

2011-05-01

The preventive effect of hawthorn (Crataegus microphylla) fruit extract against genotoxicity induced by methyl methanesulfonate (MMS) has been investigated in human cultured blood lymphocytes. Peripheral blood samples were collected from human volunteers at 0 (10 minutes before), and at 1 and 2 hours after a single oral ingestion of 1 g hawthorn powder extract. At each time point, the whole blood was treated in vitro with MMS (200 µmol) at 24 hours after cell culture, and then the lymphocytes were cultured with mitogenic stimulation to determine the micronuclei in cytokinesis-blocked binucleated cells. The lymphocytes treated with hawthorn and MMS to exhibit a significant decreasing in the incidence of micronucleated binucleated cells, as compared with similarly MMS-treated lymphocytes from blood samples collected at 0 hour. The maximum protection and decreasing in frequency of micronuclei (36%) was observed at 1 hour after ingestion of hawthorn extract. The high performance liquid chromatography (HPLC) analysis showed that hawthorn contained chlorogenic acid, epicatechin and hyperoside. It is obvious that hawthorn, particularly flavonoids constituents with antioxidative activity, reduced the oxidative stress and genotoxicity induced by toxic compounds. This set of data may have an important application for the protection of human lymphocyte from the genetic damage and side effects induced by chemicals hazardous in people.

Electrocardiographic effects of hawthorn (Crataegus oxyacantha) in healthy volunteers: A randomized controlled trial.

PubMed

Trexler, Stephanie E; Nguyen, Elaine; Gromek, Samantha M; Balunas, Marcy J; Baker, William L

2018-04-19

The objective of this study was to evaluate the electrocardiographic effects of hawthorn in healthy adult volunteers. It was double-blind cross-over trial randomized 20 healthy adult volunteers to receive either a single oral 160-mg dose of hawthorn or matching placebo. Triplicate 12-lead electrocardiograms were taken before treatment and at 1-, 2-, 4-, and 6-hr post-dose. Following at least a 7-day washout period, participants were crossed over to the opposing treatment arm and had the measurements repeated. The primary endpoint was the change in corrected (Fridericia) QT intervals (QT c I) at 4 and 6 hr. Maximum post-dose QT c I and changes in PR and QRS intervals were measured. No significant differences in 4- or 6-hr QT c I were seen between hawthorn and placebo. Maximum post-dose QT c I in the hawthorn and placebo groups were similar (346 ± 35 vs 346 ± 40 ms; p = .979). No significant adverse events were seen. In conclusion, a single dose of oral hawthorn had no effect on electrocardiographic parameters in healthy volunteers. Copyright © 2018 John Wiley & Sons, Ltd.

[Stability of physical state on compound hawthorn dropping pills].

PubMed

Zhang, Wei; Chen, Hong-Yan; Jiang, Jian-Lan

2008-11-01

To evaluate the stability of physical state with accelerate test and dropping in process before and after on compound hawthorn dropping pills. Scanning electron microscope, TG-DTA, FT-IR and XRD were used. The active components presented amorphous, tiny crystal and molecular state in dropping pills, and it had no obvious reaction between PEG 4000 and active components. With time prolonging, a little of active components changed from amorphous state to tiny crystal or molecular state. Solid dispersion improved the stability and dissolution of compound hawthorn dropping pills.

Study on antibacterial effect of medlar and hawthorn compound extract in vitro.

PubMed

Niu, Yang; Nan, Yi; Yuan, Ling; Wang, Rong

2013-01-01

This paper evaluated the antibacterial effect of medlar and hawthorn compound extract in vitro. Water extract method and ethanol extraction method was adopted to prepare the compound extracts, and disc diffusion method and improved test tube doubling dilution method were used to conduct the antibacterial test on the two common pathogenic bacteria, Staphylococcus aureus and Klebsiella pneumonia, in vitro. The results showed that medlar and hawthorn compound extract was moderately sensitive to Staphylococcus aureus, while its inhibiting effect on Klebsiella pneumoniae was particularly significant, moreover, the antibacterial effect of ethanol extract was better than water extract. Medlar and hawthorn compounds had good antibacterial effect on the two pathogenic bacteria.

77 FR 30884 - Amendment of Restricted Area R-2502E; Fort Irwin, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-24

...-0461; Airspace Docket No. 12-AWP-1] RIN 2120-AA66 Amendment of Restricted Area R-2502E; Fort Irwin, CA... designated controlling agency for restricted area R-2502E, Fort Irwin, CA, from the Federal Aviation... Airspace System, the FAA is changing the assigned controlling agency for restricted area R-2502E, Fort...

Hawthorn Fruit Extract Elevates Expression of Nrf2/HO-1 and Improves Lipid Profiles in Ovariectomized Rats

PubMed Central

Yoo, Jeong-Hyun; Liu, Yanan; Kim, Hyun-Sook

2016-01-01

The purpose of this study was to investigate the effects of hawthorn (Crataegus pinnatifida Bunge) extract on the lipid profiles and antioxidant properties in ovariectomized (OVX) rats. After ovariectomy, the rats were randomly divided into four groups: the non-OVX control (Sham), the OVX-control (OVX), the OVX + 100 mg/kg b.w. of hawthorn extract (OL), and the OVX + 200 mg/kg b.w. of hawthorn extract (OH). The final body weights of the OVX group were significantly increased, but the increment was significantly decreased in hawthorn groups (p < 0.05). The serum total and low-density lipoprotein (LDL) cholesterol levels were significantly elevated in the OVX group, whereas the hawthorn groups showed a significant decrease in these levels (p < 0.05). The hepatic triglyceride (TG) and malondialdehyde (MDA) levels were significantly reduced in the hawthorn groups compared with the OVX group (p < 0.05). The mRNA expression of nuclear factor erythroid 2–related factor (Nrf2), heme oxygenase-1 (HO-1), and glutathione peroxidase (GPx) were significantly decreased in the OVX group, whereas the hawthorn groups exhibited a significant increase in expression (p < 0.05). The protein expressions of Nrf2, HO-1, and GPx were lower in the OVX group than the Sham group (p < 0.05). The oral administration of hawthorn extract reversed the suppression of protein levels. These results suggest that hawthorn extract could have protective effects in OVX rats by improving lipid profiles, decreasing oxidative stress, and improving the antioxidant defense system. PMID:27187458

Hawthorn Fruit Extract Elevates Expression of Nrf2/HO-1 and Improves Lipid Profiles in Ovariectomized Rats.

PubMed

Yoo, Jeong-Hyun; Liu, Yanan; Kim, Hyun-Sook

2016-05-13

The purpose of this study was to investigate the effects of hawthorn (Crataegus pinnatifida Bunge) extract on the lipid profiles and antioxidant properties in ovariectomized (OVX) rats. After ovariectomy, the rats were randomly divided into four groups: the non-OVX control (Sham), the OVX-control (OVX), the OVX + 100 mg/kg b.w. of hawthorn extract (OL), and the OVX + 200 mg/kg b.w. of hawthorn extract (OH). The final body weights of the OVX group were significantly increased, but the increment was significantly decreased in hawthorn groups (p < 0.05). The serum total and low-density lipoprotein (LDL) cholesterol levels were significantly elevated in the OVX group, whereas the hawthorn groups showed a significant decrease in these levels (p < 0.05). The hepatic triglyceride (TG) and malondialdehyde (MDA) levels were significantly reduced in the hawthorn groups compared with the OVX group (p < 0.05). The mRNA expression of nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1), and glutathione peroxidase (GPx) were significantly decreased in the OVX group, whereas the hawthorn groups exhibited a significant increase in expression (p < 0.05). The protein expressions of Nrf2, HO-1, and GPx were lower in the OVX group than the Sham group (p < 0.05). The oral administration of hawthorn extract reversed the suppression of protein levels. These results suggest that hawthorn extract could have protective effects in OVX rats by improving lipid profiles, decreasing oxidative stress, and improving the antioxidant defense system.

Classification and phylogenetic analysis of Chinese hawthorn assessed by plant and pollen morphology.

PubMed

Ma, S L Y; Lu, Y M

2016-09-19

The Chinese hawthorn (Crataegus pinnatifida Bge. var. major N.E.Br.) is uniquely originated in northern China. The ecological and horticultural importance of Chinese hawthorn is considerable and some varieties are valued for their fruit or medicine extracts. Its taxonomy and phylogeny remain poorly understood. Apart from general plant morphological traits, pollen is an important trait for the classification of plants and their evolutionary origin. However, few studies have investigated the pollen of Chinese hawthorn. Here, an analysis of plant and pollen morphological characteristics was conducted in 57 cultivars from the Shenyang region. Thirty plant morphological characters and nine pollen grain characters were investigated. The plant morphological analysis revealed that the coefficient of variation for 13 traits was >20%, which indicates a high degree of variability. We also found that the pollen grains varied greatly in size, shape (from prolate to perprolate), and exine pattern (striate-perforate predominantly). The number of apertures was typically three. Based on these findings, we suggest that pollen morphology associated with plant morphological traits can be used for classification and phylogenetic analysis of Chinese hawthorn cultivars. In sum, our results provide new insights and constitute a scientific basis for future studies on the classification and evolution of Chinese hawthorn.

Protective effect of hawthorn extract against genotoxicity induced by cyclophosphamide in mouse bone marrow cells.

PubMed

Hosseinimehr, Seyed Jalal; Azadbakht, Mohammad; Abadi, Atefeh Jahan

2008-01-01

The preventive effect of hawthorn (Crataegus microphylla) fruit extract was investigated in mouse bone marrow cells against genotoxicity induced by cyclophosphamide. Mice were orally (gavages) pretreated with solutions of hawthorn extract which was prepared at five different doses (25, 50, 100, 200 and 400mg/kg b.w.) for seven consecutive days. Mice were injected intraperitoneally on the seventh day with cyclophosphamide (50mg/kg b.w.) and killed after 24h for the evaluation of micronucleated polychromatic erythrocytes (MnPCEs) and the ratio of PCE/(PCE+NCE) (polychromatic erythrocyte/polychromatic erythrocyte+normochromatic erythrocyte). All of five doses of extract significantly reduced MnPCEs induced by cyclophosphamide (P<0.0001). Hawthorn extract at dose 100mg/kg b.w. reduced MnPCEs 2.5 time and also completely normalized PCE/(PCE+NCE) ratio. Hawthorn extract exhibited concentration-dependent antioxidant activity on 1,1-diphenyl-2-picryl hydrazyl free radical. Hawthorn contains high amounts of phenolic compounds; the HPLC analysis showed that it contained chlorogenic acid, epicatechin and hyperoside. It is obvious that hawthorn, particularly flavonoids constituents with antioxidative activity, reduced the oxidative stress and genotoxicity induced by cyclophosphamide in mouse bone marrow cells. Copyright © 2007 Elsevier B.V. All rights reserved.

Natural Arsenic in the Miocene Hawthorn Group, Florida: Wide Ranging Implications for ASR, Phosphate Mining, Private Well

NASA Astrophysics Data System (ADS)

Lazareva, O. V.; Pichler, T.

2004-12-01

In order to understand the mineralogical association and distribution of arsenic (As) in the Hawthorn Group we examined in detail the chemical and mineralogical composition of 370 samples that were collected from 16 cores in central Florida. In our study area the Hawthorn group consists primarily of a basal carbonate unit (the Arcadia Formation) and an upper siliciclastic unit (The Peace River Formation). The Peace River Formation contains appreciable amounts of phosphate and is currently being exploited for phosphate ore. Samples were taken for each Formation at intervals of 25ft. In addition to the interval samples we also took samples that contained visible pyrite crystals, iron oxides, green clays, phosphatic and organic material. These additional samples were collected because of their potential of high As concentrations. Arsenic concentrations were determined by hydride generation - atomic fluorescence spectrometry (HG-AFS) after digestion with aqua regia (3:1 HCl and HNO3). The elements Fe, Na, Al, Si, Mg, Ca, S, P, and K were measured on the same solutions by inductively coupled plasma optical emission spectrometry (ICP-OES). The identification of discrete minerals was aided by scanning electron microscopy (SEM) and chemical compositions were obtained by electron-probe microanalyses (EMPA). Our study indicates that the average As concentrations significantly change from 9.0 ppm in the Peace River Formation to 3.0 ppm in the Tampa Member of the Arcadia Formation. As concentrations for all Hawthorn samples vary from 0.07 to 68.98 ppm ( μ = 5.6, σ = 7.1). Our detailed mineralogical and geochemical study demonstrates that: (1) The As in the Hawthorn group varies from the formation to formation and is mostly concentrated in trace minerals, such as pyrite; (2) Concentrations of the As in pyrite crystals can vary drastically from a minimum of 0 ppm to a maximum of 8260 ppm; (3) Pyrite is an unevenly distributed throughout the Hawthorn Group; (4) Phosphate and

Identification of host fruit volatiles from domestic apple (Malus domestica), native black hawthorn (Crataegus douglasii) and introduced ornamental hawthorn (C. monogyna) attractive to R. pomonella flies from the western U.S.

USDA-ARS?s Scientific Manuscript database

The apple maggot fly, Rhagoletis pomonella, infests apple (Malus domestica) and hawthorn species (most notably the downy hawthorn, Crataegus mollis) in the eastern USA. Evidence suggests that the fly was introduced into the western USA sometime in the last 60 years. In addition to apple, R. pomonel...

Hawthorn Herb Increases the Risk of Bleeding after Cardiac Surgery: An Evidence-Based Approach.

PubMed

Rababa'h, Abeer M; Altarabsheh, Salah E; Haddad, Osama; Deo, Salil V; Obeidat, Yagthan; Al-Azzam, Sayer

2016-08-22

Hawthorn extract consumption is becoming more widespread among the Jordanian population with cardiovascular disorders. We conducted this prospective observational longitudinal study to determine the impact of hawthorn extract on bleeding risk in patients who undergo cardiac surgery. A prospective observational study was performed on 116 patients who underwent cardiac surgery in the period between June 2014 and May 2015. Patients were divided into two groups: Group I (patients recently consumed hawthorn extract) and Group II (patients never consumed hawthorn extract). Endpoint measures included the rates of reopening to control bleeding, early mortality, duration of intensive care unit stay, total in-hospital stay period, and duration and amount of chest tube drainage. Hawthorn patients had a significantly higher rate of postoperative bleeding necessitating take back to the operating room compared to the control group (10% versus 1%; P = .03) respectively. The overall mortality rate for group I and II was 4% and 0% respectively; P = .17. Chest tubes were kept in for longer times in group I compared to group II (54 ± 14.6 versus 49 ± 14.7 hours respectively; P = .01). Group I stayed longer in the intensive care unit compared to group II (24 versus 22 hours respectively; P = .01). The total in-hospital stay period was comparable between the two groups. Hawthorn extract consumption does increase the potential for bleeding and the amount of chest tube output after cardiac surgery.

78 FR 72006 - Establishment of Class D Airspace and Class E Airspace; Laguna AAF, AZ

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-02

... establishes Class D airspace and Class E airspace at Laguna Army Air Field (AAF), (Yuma Proving Ground), Yuma...) within a 3.5- mile radius of Laguna AAF (Yuma Proving Ground), Yuma, AZ; and Class E airspace extending... scope of that authority as it establishes controlled airspace at Laguna AAF, (Yuma Proving Ground), Yuma...

75 FR 65250 - Proposed Amendment of Class E Airspace and Revocation of Class E Airspace; Easton, MD

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-22

... rulemaking (NPRM). SUMMARY: This action proposes to modify Class E surface airspace and airspace 700 feet... modify Class E surface airspace and Class E airspace extending upward from 700 feet above the surface to... Class E airspace extending upward from 700 feet above the surface are published in Paragraph 6002, 6004...

75 FR 226 - Establishment of Class E Airspace; Riverside/Rubidoux Flabob Airport, Riverside, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-05

... Lind Avenue, SW., Renton, WA 98057; telephone (425) 203-4537. SUPPLEMENTARY INFORMATION: History On... 6005 Class E airspace areas extending upward from 700 feet or more above the surface of the earth...

Hawthorn fruit attenuates atherosclerosis by improving the hypolipidemic and antioxidant activities in apolipoprotein e-deficient mice.

PubMed

Zhang, Yuying; Zhang, Liang; Geng, Yue; Geng, Yunhong

2014-01-01

The protective effects of hawthorn fruit against atherosclerosis and the potential underlying mechanisms of this fruit in improving the hypolipidemic and antioxidant activities were investigated in apolipoprotein E-deficient(apoE(-/-)) mice. ApoE(-/-) mice were divided into a control group(n=10) and hawthorn fruit group(n=10). The mean size of the lesions in the aortic root was assessed, and the serum glucose levels, insulin levels, lipid profiles, total antioxidant capacity(T-AOC) and superoxide dismutase(SOD) and glutathione peroxidase(GSH-PX) activities were measured. The mRNA levels of hepatic genes related to lipid metabolism and antioxidant enzymes were examined. The hawthorn fruit group mice developed significantly decreased(p＜0.05) atherosclerotic lesions. The levels of serum lipids decreased significantly(p＜0.05) and the levels of cholesterol/triglycerides, including very-low-density lipoprotein(VLDL) and low-density lipoprotein(LDL), decreased in the hawthorn fruit group. The hawthorn fruit mice exhibited significantly increased T-AOC values and SOD and GSH-PX activities(p＜0.05). The hepatic fatty acid synthase(FAS) and sterol regulatory element binding protein-1c(SREBP-1c) mRNA levels were reduced by 42%(p＜0.05) and 23% p＜0.05) in the mice fed the hawthorn fruit diet compared with that observed in the mice fed a standard diet. However, the hepatic hydroxymethylglutaryl CoA reductase(HMG-CoAR) mRNA levels showed no significant differences between the two groups. The mRNA expression levels of the antioxidant enzymes(SOD1, SOD2, Gpx3) were higher(p＜0.05) in the livers of the hawthorn fruit diet mice compared with those observed in the control mice. Hawthorn fruit exerts a protective effect against atherosclerosis in apoE(-/-) mice by improving the hypolipidemic and antioxidant activities.

Assessment of phenolic acid content and in vitro antiradical characteristics of hawthorn.

PubMed

Öztürk, Nilgün; Tunçel, Muzaffer

2011-06-01

The infusions and extracts obtained from leaves with flowers, fruit peel, and seed from hawthorn (Crataegus monogyna Jacq., Family Rosaceae) were subjected to evaluation as potential sources of antioxidant phytochemicals on the basis of their total content of phenolics, levels of phenolic acids, and in vitro antiradical activity. Total phenolic content of extracts was determined using the modified Folin-Ciocalteau method. Antioxidant activity was determined for phenolic extracts by a method involving the use of the free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH). Phenolic acids containing extracts and infusions from hawthorn leaves, fruit peel, and seeds were obtained using different polarity solvents and separated by reverse-phase high-performance liquid chromatography, which enabled improved separation by the use of a C(18) column, an acidic mobile phase, and gradient elusion. The highest total phenolic content (343.54 mg of gallic acid equivalents/g) and the highest DPPH radical scavenging activity as the inhibition percentage (60.36%) were obtained in ethyl acetate extract from hawthorn leaves with flower. Also, the highest phenolic acid content was measured in the extracts of hawthorn leaves with flowers: protocathechuic (108-128 mg/100 g), p-hydroxy benzoic (141-468 mg/100 g), caffeic (137-3,580 mg/100 g), chlorogenic (925-4,637 mg/100 g), ferulic (3,363-3,462 mg/100 g), vanillic (214 mg/100 g), and syringic (126 mg/100 g) acids. The results indicate that hawthorn is a promising plant because of its high antioxidant activity.

The Hawthorne experiments and the introduction of Jean Piaget in American industrial psychology, 1929-1932.

PubMed

Hsueh, Yeh

2002-05-01

The Hawthorne interview program between 1929 and 1932 was one of the most significant industrial studies in the United States. The Hawthorne researchers applied Jean Piaget's clinical method in their extensive interviews with tens of thousands of workers. Chiefly responsible for the program's methodology was Elton Mayo, an Australian who saw interviewing as a means to promote social cooperation. Previous discussions of the Hawthorne experiments have ignored the influence of Piaget in the social sciences. This article provides an account of Mayo's and the Hawthorne researchers' efforts to fuse Piaget's innovation with burgeoning American industrial psychology. The endeavor was not an isolated event but rather drew on the theories and practice of Janet-Piaget psychology, on the support of the Laura Spelman Rockefeller Memorial Foundation, and on the discourse among social scientists about Piaget's work.

Transcript Assembly and Quantification by RNA-Seq Reveals Differentially Expressed Genes between Soft-Endocarp and Hard-Endocarp Hawthorns

PubMed Central

Zhang, Feng; Liu, Zhongchi; Li, Xiaoming; Li, Wenran; Ma, Yue; Li, He; Liu, Yuexue; Zhang, Zhihong

2013-01-01

Hawthorn (Crataegus spp.) is an important pome with a long history as a fruit, an ornamental, and a source of medicine. Fruits of hawthorn are marked by hard stony endocarps, but a hawthorn germplasm with soft and thin endocarp was found in Liaoning province of China. To elucidate the molecular mechanism underlying the soft endocarp of hawthorn, we conducted a de novo assembly of the fruit transcriptome of Crataegus pinnatifida and compared gene expression profiles between the soft-endocarp and the hard-endocarp hawthorn varieties. De novo assembly yielded 52,673 putative unigenes, 20.4% of which are longer than 1,000 bp. Among the high-quality unique sequences, 35,979 (68.3%) had at least one significant match to an existing gene model. A total of 1,218 genes, represented 2.31% total putative unigenes, were differentially expressed between the soft-endocarp hawthorn and the hard-endocarp hawthorn. Among these differentially expressed genes, a number of lignin biosynthetic pathway genes were down-regulated while almost all the flavonoid biosynthetic pathway genes were strongly up-regulated, concomitant with the formation of soft endocarp. In addition, we have identified some MYB and NAC transcription factors that could potentially control lignin and flavonoid biosynthesis. The altered expression levels of the genes encoding lignin biosynthetic enzymes, MYB and NAC transcription factors were confirmed by quantitative RT-PCR. This is the first transcriptome analysis of Crataegus genus. The high quality ESTs generated in this study will aid future gene cloning from hawthorn. Our study provides important insights into the molecular mechanisms underlying soft endocarp formation in hawthorn. PMID:24039819

Composition and health effects of phenolic compounds in hawthorn (Crataegus spp.) of different origins.

PubMed

Yang, Baoru; Liu, Pengzhan

2012-06-01

Epicatechin, aglycons and glycosides of B-type oligomeric procyanidins and flavonols, phenolic acids and C-glycosyl flavones are the major groups of phenolic compounds in hawthorn (Crataegus spp). The total content of phenolic compounds is higher in the leaves and flowers than in the fruits. Procyanidins dominate in the fruits, whereas flavonol glycosides and C-glycosyl flavones are most abundant in the leaves. Genotype and developmental/ripening stage have strong impacts. Procyanidin glycosides and C-glycosyl flavones may be chemotaxonomic markers differentiating species and varieties of hawthorn. Future research shall improve the separation, identification and quantification of procyanidins with degree of polymerisation (DP) ≥ 6, procyanidin glycosides, C-glycosyl flavones and some flavonol glycosides. In vitro and animal studies have shown cardioprotective, hypolipidaemic, hypotensive, antioxidant, radical-scavenging and anti-inflammatory potentials of hawthorn extracts, suggesting different phenolic compounds as the major bioactive components. However, the varying and insufficiently defined composition of the extracts investigated, as a result of different raw materials and extraction methods, makes comparison of the studies very difficult. Clinical evidence indicates that some hawthorn extracts may increase the exercise tolerance of patients with congestive heart failure. More clinical studies are needed to establish the effects of hawthorn, especially in healthy humans. Copyright © 2012 Society of Chemical Industry.

78 FR 33015 - Proposed Amendment of Class D Airspace; Waco, TX, and Establishment of Class D Airspace; Waco...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-03

...-0136; Airspace Docket No. 13-ASW-4] Proposed Amendment of Class D Airspace; Waco, TX, and Establishment of Class D Airspace; Waco, TSTC-Waco Airport, TX AGENCY: Federal Aviation Administration (FAA), DOT... Waco, TX, by separating the Class D airspace at Waco Regional Airport from the Class D airspace at TSTC...

The airspace is habitat

USGS Publications Warehouse

Diehl, Robert H.

2013-01-01

A preconception concerning habitat persists and has gone unrecognized since use of the term first entered the lexicon of ecological and evolutionary biology many decades ago. Specifically, land and water are considered habitats, while the airspace is not. This might at first seem a reasonable, if unintended, demarcation, since years of education and personal experience as well as limits to perception predispose a traditional view of habitat. Nevertheless, the airspace satisfies the definition and functional role of a habitat, and its recognition as habitat may have implications for policy where expanding anthropogenic development of airspace could impact the conservation of species and subject parts of the airspace to formalized legal protection.

Effect of hawthorn (Crataegus oxycantha) crude extract and chromatographic fractions on multiple activities in a cultured cardiomyocyte assay.

PubMed

Long, S R; Carey, R A; Crofoot, K M; Proteau, P J; Filtz, T M

2006-11-01

Extracts of hawthorn (Crataegus oxycantha) have become popular herbal supplements for their well-recognized cardiotonic effects. Many commercial preparations have been used successfully in the treatment of congestive heart failure, although the active principles within these extracts have yet to be conclusively identified. Several hawthorn preparations were studied and found to have negative chronotropic effects in a cultured neonatal murine cardiomyocyte assay using unpaced cells. As compared to conventional cardiac drugs (i.e., epinephrine, milrinone, ouabain, or propranolol), hawthorn extract has a unique activity profile. Hawthorn extract appears to be anti-arrhythmic and capable of inducing rhythmicity in quiescent cardiomyocytes. Hawthorn extract does not cause beta-adrenergic receptor blockade at concentrations which cause negative chronotropic effects. Commercial hawthorn preparations, extracts prepared from dried leaves and those made from dried berries have similar chronotropic activities. When crude extracts are separated using size-exclusion chromatography, several fractions retain multiple cardiac activities. Assays with chromatographic fractions reveal that multiple dissimilar cardioactive components may exist within the extract, making the identification of individual active constituents more challenging.

[Key physical parameters of hawthorn leaf granules by stepwise regression analysis method].

PubMed

Jiang, Qie-Ying; Zeng, Rong-Gui; Li, Zhe; Luo, Juan; Zhao, Guo-Wei; Lv, Dan; Liao, Zheng-Gen

2017-05-01

The purpose of this study was to investigate the effect of key physical properties of hawthorn leaf granule on its dissolution behavior. Hawthorn leaves extract was utilized as a model drug. The extract was mixed with microcrystalline cellulose or starch with the same ratio by using different methods. Appropriate amount of lubricant and disintegrating agent was added into part of the mixed powder, and then the granules were prepared by using extrusion granulation and high shear granulation. The granules dissolution behavior was evaluated by using equilibrium dissolution quantity and dissolution rate constant of the hypericin as the indicators. Then the effect of physical properties on dissolution behavior was analyzed through the stepwise regression analysis method. The equilibrium dissolution quantity of hypericin and adsorption heat constant in hawthorn leaves were positively correlated with the monolayer adsorption capacity and negatively correlated with the moisture absorption rate constant. The dissolution rate constants were decreased with the increase of Hausner rate, monolayer adsorption capacity and adsorption heat constant, and were increased with the increase of Carr index and specific surface area. Adsorption heat constant, monolayer adsorption capacity, moisture absorption rate constant, Carr index and specific surface area were the key physical properties of hawthorn leaf granule to affect its dissolution behavior. Copyright© by the Chinese Pharmaceutical Association.

Airspace Control

DTIC Science & Technology

2011-02-02

This Doctrine Update highlights the revision of AFDD 3-52, Airspace Control, dated 2 February 2011. The AFDD was substantially revised...and must be completely reviewed. The format of the publication was changed to adhere to the LeMay Center doctrine document template and increases the...particular airspace control considerations in crisis response and in limited contingency operations. (Page 30) • Introducing to Air Force doctrine

Radioprotective effects of hawthorn fruit extract against gamma irradiation in mouse bone marrow cells.

PubMed

Hosseinimehr, Seyed Jalal; Azadbakht, Mohammad; Mousavi, Seyedeh Maryam; Mahmoudzadeh, Aziz; Akhlaghpoor, Shahram

2007-01-01

The radioprotective effect of hawthorn (Crataegus microphylla) fruit extract against genotoxicity induced by gamma irradiation has been investigated in mouse bone marrow cells. A single intraperitoneal (ip) administration of hawthorn extract at doses of 25, 50, 100 and 200 mg/kg 1h prior to gamma irradiation (2 Gy) reduced the frequencies of micronucleated polychromatic erythrocytes (MnPCEs). All four doses of hawthorn extract significantly reduced the frequencies of MnPCEs and increased the PCE/PCE+NCE ratio (polychromatic erythrocyte/ polychromatic erythrocyte + normochromatic erythrocyte) in mice bone marrow compared with the non drug-treated irradiated control (p < 0.02-0.00001). The maximum reduction in MnPCEs was observed in mice treated with extract at a dose of 200 mg/kg. Administration of amifostine at dose 100 mg/kg and hawthorn at dose 200 mg/kg reduced the frequency of MnPCE almost 4.8 and 5.7 fold; respectively, after being exposed to 2 Gy of gamma rays, compare with the irradiated control group. Crataegus extract exhibited concentration-dependent activity on 1,1-diphenyl 2-picrylhydrazyl free radical showing that Crataegus contained high amounts of phenolic compounds and the HPLC analysis determined that it contained chlorogenic acid, epicatechin and hyperoside. It appeared that hawthorn extract with antioxidant activity reduced the genotoxicity induced by gamma irradiation in bone marrow cells.

78 FR 48290 - Amendment of Class D Airspace; Waco, TX, and Establishment of Class D Airspace; Waco, TSTC-Waco...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-08

...-0136; Airspace Docket No. 13-ASW-4] Amendment of Class D Airspace; Waco, TX, and Establishment of Class D Airspace; Waco, TSTC-Waco Airport, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class D airspace at Waco, TX, by separating the Class D airspace...

The 2011 Hawthorne, Nevada, Earthquake Sequence; Shallow Normal Faulting

NASA Astrophysics Data System (ADS)

Smith, K. D.; Johnson, C.; Davies, J. A.; Agbaje, T.; Knezevic Antonijevic, S.; Kent, G.

2011-12-01

An energetic sequence of shallow earthquakes that began in early March 2011 in western Nevada, near the community of Hawthorne, has slowly decreased in intensity through mid-2011. To date about 1300 reviewed earthquake locations have been compiled; we have computed moment tensors for the larger earthquakes and have developed a set of high-precision locations for all reviewed events. The sequence to date has included over 50 earthquakes ML 3 and larger with the largest at Mw 4.6. Three 6-channel portable stations configured with broadband sensors and accelerometers were installed by April 20. Data from the portable instruments is telemetered through NSL's microwave backbone to Reno where it is integrated with regional network data for real-time notifications, ShakeMaps, and routine event analysis. The data is provided in real-time to NEIC, CISN and the IRIS DMC. The sequence is located in a remote area about 15-20 km southwest of Hawthorne in the footwall block of the Wassuk Range fault system. An initial concern was that the sequence might be associated with volcanic processes due to the proximity of late Quaternary volcanic flows; there have been no volcanic signatures observed in near source seismograms. An additional concern, as the sequence has proceeded, was a clear progression eastward toward the Wassuk Range front fault. The east dipping range bounding fault is capable of M 7+ events, and poses a significant hazard to the community of Hawthorne and local military facilities. The Hawthorne Army Depot is an ordinance storage facility and the nation's storage site for surplus mercury. The sequence is within what has been termed the 'Mina Deflection' of the Central Walker Lane Belt. Faulting along the Whiskey Flat section of the Wassuk front fault would be primarily down-to-the-east, with an E-W extension direction; moment tensors for the 2011 earthquake show a range of extension directions from E-W to NW-SE, suggesting a possible dextral component to the Wassuk

14 CFR 71.51 - Class C airspace.

Code of Federal Regulations, 2013 CFR

2013-01-01

... DESIGNATION OF CLASS A, B, C, D, AND E AIRSPACE AREAS; AIR TRAFFIC SERVICE ROUTES; AND REPORTING POINTS Class C Airspace § 71.51 Class C airspace. The Class C airspace areas listed in subpart C of FAA Order... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Class C airspace. 71.51 Section 71.51...

14 CFR 71.51 - Class C airspace.

Code of Federal Regulations, 2010 CFR

2010-01-01

... DESIGNATION OF CLASS A, B, C, D, AND E AIRSPACE AREAS; AIR TRAFFIC SERVICE ROUTES; AND REPORTING POINTS Class C Airspace § 71.51 Class C airspace. The Class C airspace areas listed in subpart C of FAA Order... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Class C airspace. 71.51 Section 71.51...

Radioprotective effects of Hawthorn against genotoxicity induced by gamma irradiation in human blood lymphocytes.

PubMed

Hosseinimehr, Seyed Jalal; Mahmoudzadeh, Aziz; Azadbakht, Mohammad; Akhlaghpoor, Shahram

2009-02-01

The radioprotective effect of hawthorn (Crataegus microphylla) fruit extract was investigated in cultured blood lymphocytes from human volunteers. Peripheral blood samples were collected from five human volunteers 10 min before and 1, 2 and 3 h after a single oral ingestion of 500 mg hawthorn powder extract. At each time point, the whole blood was exposed in vitro to 150 cGy of cobalt-60 gamma irradiation, and then the lymphocytes were cultured with mitogenic stimulation to determine the micronuclei in cytokinesis-blocked binucleated cell. The lymphocytes in the blood samples collected after extract ingestion exhibited a significant decrease in the incidence of binucleated cells containing micronuclei as compared to similarly irradiated lymphocytes collected prior to extract ingestion. The maximum decrease in the frequency of micronuclei-containing cells was observed at 1 h after ingestion of Hawthorn extract (on average a 44% decrease). These data suggest that it may be possible to use Hawthorn extracts in personnel exposed to radiation in order to protect lymphocytes from radiation effects.

Polyphenolic profile and biological activity of Chinese hawthorn (Crataegus pinnatifida BUNGE) fruits.

PubMed

Jurikova, Tunde; Sochor, Jiri; Rop, Otakar; Mlcek, Jiri; Balla, Stefan; Szekeres, Ladislav; Adam, Vojtech; Kizek, Rene

2012-12-06

Chinese hawthorn (Crataegus pinnatifida Bge.) fruits are rich in polyphenols (e.g., epicatechin, procyanidin B2, procyanidin B5, procyanidin C1, hyperoside, isoquercitrin and chlorogenic acid)--active compounds that exert beneficial effects. This review summarizes all information available on polyphenolic content and methods for their quantification in Chinese hawthorn berries and the relationships between individual polyphenolic compounds as well. The influence of species or cultivars, the locality of cultivation, the stage of maturity, and extract preparation conditions on the polyphenolic content were discussed as well. Currently, only fruits of C. pinnatifida and C. pinnatifida var. major are included in the Chinese Pharmacopoeia. Recent trials have demonstrated the efficacy of Chinese hawthorn fruit in lowering blood cholesterol and the risk of cardiovascular diseases. The fruit has also demonstrated anti-inflammatory and anti-tumour activities. This review deals mainly with the biological activity of the fruit related to its antioxidant properties.

Airspace Technology Demonstration 2 (ATD-2) Integrated Surface and Airspace Simulation - Experiment Plan

NASA Technical Reports Server (NTRS)

Verma, Savita Arora; Jung, Yoon Chul

2017-01-01

This presentation describes the overview of the ATD-2 project and the integrated simulation of surface and airspace to evaluate the procedures of IADS system and evaluate surface metering capabilities via a high-fidelity human-in-the-loop simulation. Two HITL facilities, Future Flight Central (FFC) and Airspace Operations Laboratory (AOL), are integrated for simulating surface operations of the Charlotte-Douglas International Airport (CLT) and airspace in CLT TRACON and Washington Center.

Antitumoral, antioxidant, and antimelanogenesis potencies of Hawthorn, a potential natural agent in the treatment of melanoma.

PubMed

Mustapha, Nadia; Mokdad-Bzéouich, Imèn; Maatouk, Mouna; Ghedira, Kamel; Hennebelle, Thierry; Chekir-Ghedira, Leila

2016-06-01

The lack of an efficient agent that does not have the disadvantage of low activity (kojic acid), high cytotoxicity, and mutagenicity (hydroquinone), poor skin penetration (arbutin), or low stability in formulation (glabridin) led us to continue our research on new antipigmentation/skin-lightening agents. Therefore, research of natural products that can modulate the metabolism of pigmentation is of great interest. Otherwise, malignant melanoma is one of the most aggressive forms of skin cancer, with high metastatic potential, and currently, there is no effective chemotherapy against invasive melanoma. Therefore, it is necessary to develop new drugs with potent activity and weak side effects against melanoma. The in-vitro anticancer effect of hawthorn was analyzed against B16F10 melanoma cells using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. The effect of isolated compounds from hawthorn on melanogenesis in B16F10 melanoma cells was investigated by measuring the amounts of melanin and tyrosinase spectrophotometrically at 475 nm. Balb/c mice models inoculated with B16F10 mouse tumor cells were used to evaluate the in-vivo antitumoral potential of hawthorn by assessing its effect on the growth of transplanted tumors. The antioxidant potential of tested samples was evaluated in B16F10 and primary human keratinocyte cells using a cellular antioxidant activity assay. Hawthorn tested samples inhibited effectively the growth of melanoma cells in vitro. Furthermore, it appears that tested samples from hawthorn reduced melanogenesis by inhibiting the tyrosinase activity of B16F10 cells in a dose-dependent manner. In-vivo studies showed that hawthorn total oligomer flavonoids extract treatment at a dose of 150 mg/kg body weight for 21 days in implanted tumor mice resulted in significant inhibition of the tumor growth volume and weight. In addition, tested samples showed significant cellular antioxidant capacity against the reactive oxygen species

75 FR 57848 - Revocation of Class E Airspace, Brunswick, ME; and Establishment of Class E Airspace, Wiscasset, ME

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-23

...-0248; Airspace Docket No. 10-ANE-10] Revocation of Class E Airspace, Brunswick, ME; and Establishment of Class E Airspace, Wiscasset, ME AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action removes Class E Airspace at Brunswick NAS, Brunswick, ME, as the airport has...

Advanced Airspace Concept

NASA Technical Reports Server (NTRS)

Erzberger, Heinz

2002-01-01

A general overview of the Advanced Airspace Concept (AAC) is presented. The topics include: 1) Limitations of the existing system; 2) The Advanced Airspace Concept; 3) Candidate architecture for the AAC; 4) Separation assurance and conflict avoidance system (TSAFE); and 5) Ground-Air Interactions. This paper is in viewgraph form.

Energy Engineering Analysis Program, limited energy study of steam distribution systems, Hawthorne Army Ammunition Depot, Hawthorne, Nevada. Programming documents

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-09-01

The project is a significant part of Hawthorne Army Ammunition Depot`s effort to achieve a 20-percent reduction in energy consumption by FY2000 versus FY1985 baseline levels. The project will also assure that heating services are provided to Industrial Area facilities on a continuing basis, supporting mission requirements.

Fourth Period Discovers Hester as Mother: Hawthorne's Mother?

ERIC Educational Resources Information Center

Heginbotham, Eleanor

1986-01-01

A teacher discusses how she used criticism of "The Scarlet Letter," when studying the book, in her honors class. The students were also intrigued by the biographical information they learned about Hawthorne, and eager to use it in interpreting his novel. (SRT)

Preparative isolation of oligomeric procyanidins from Hawthorn (Crataegus spp.).

PubMed

Zumdick, S; Petereit, F; Luftmann, H; Hensel, A

2009-04-01

The oligomeric procyanidins (OPC) from Hawthorn leaves and flowers (Crataegi folium cum flore) are considered to be in part responsible for the cardiotonic clinical activity of the herbal material. Effective methods for rapid isolation of these heterogenous oligomeric clusters with defined molecular weight as reference compounds are not published until now. Therefore the water soluble fraction of an acetone/water (7 + 3) extract of Hawthorn leaves and flowers was fractionated by a combination of MPLC on RP-18 material and preparative HPLC using a diol stationary phase. This procedure resulted in the effective isolation of procyanidins with a distinct degree of polymerization (DP) from dimers DP2 up to tridecamers DP13. Exact mass measurements with negative ESI-TOF/MS were employed to confirm the respective structures of the isolated procyanidins.

14 CFR 71.71 - Class E airspace.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Class E airspace. 71.71 Section 71.71 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE... (2) The airspace below 1,500 feet above the surface of the earth. (b) The airspace areas designated...

Promising hypotensive effect of hawthorn extract: a randomized double-blind pilot study of mild, essential hypertension.

PubMed

Walker, Ann F; Marakis, Georgios; Morris, Andrew P; Robinson, Paul A

2002-02-01

This pilot study was aimed at investigating the hypotensive potential of hawthorn extract and magnesium dietary supplements individually and in combination, compared with a placebo. Thirty-six mildly hypertensive subjects completed the study. At baseline, anthropometric and dietary assessment, as well as blood pressure measurements were taken at rest, after exercise and after a computer 'stress' test. Volunteers were then randomly assigned to a daily supplement for 10 weeks of either: (a) 600 mg Mg, (b) 500 mg hawthorn extract, (c) a combination of (a) and (b), (d) placebo. Measurements were repeated at 5 and 10 weeks of intervention. There was a decline in both systolic and diastolic blood pressure in all treatment groups, including placebo, but ANOVA provided no evidence of difference between treatments. However, factorial contrast analysis in ANOVA showed a promising reduction (p = 0.081) in the resting diastolic blood pressure at week 10 in the 19 subjects who were assigned to the hawthorn extract, compared with the other groups. Furthermore, a trend towards a reduction in anxiety (p = 0.094) was also observed in those taking hawthorn compared with the other groups. These findings warrant further study, particularly in view of the low dose of hawthorn extract used. Copyright 2002 John Wiley & Sons, Ltd.

Intelligent aircraft/airspace systems

NASA Technical Reports Server (NTRS)

Wangermann, John P.

1995-01-01

Projections of future air traffic predict at least a doubling of the number of revenue passenger miles flown by the year 2025. To meet this demand, an Intelligent Aircraft/Airspace System (IAAS) has been proposed. The IAAS operates on the basis of principled negotiation between intelligent agents. The aircraft/airspace system today consists of many agents, such as airlines, control facilities, and aircraft. All the agents are becoming increasingly capable as technology develops. These capabilities should be exploited to create an Intelligent Aircraft/Airspace System (IAAS) that would meet the predicted traffic levels of 2005.

Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial

PubMed Central

Walker, Ann F; Marakis, Georgios; Simpson, Eleanor; Hope, Jessica L; Robinson, Paul A; Hassanein, Mohamed; Simpson, Hugh CR

2006-01-01

Background Hawthorn (Crataegus laevigata) leaves, flowers and berries are used by herbal practitioners in the UK to treat hypertension in conjunction with prescribed drugs. Small-scale human studies support this approach. Aim To investigate the effects of hawthorn for hypertension in patients with type 2 diabetes taking prescribed drugs. Design of study Randomised controlled trial. Setting General practices in Reading, UK. Method Patients with type 2 diabetes (n = 79) were randomised to daily 1200 mg hawthorn extract (n = 39) or placebo (n = 40) for 16 weeks. At baseline and outcome a wellbeing questionnaire was completed and blood pressure and fasting blood samples taken. A food frequency questionnaire estimated nutrient intake. Results Hypotensive drugs were used by 71% of the study population with a mean intake of 4.4 hypoglycaemic and/or hypotensive drugs. Fat intake was lower and sugar intake higher than recommendations, and low micronutrient intake was prevalent. There was a significant group difference in mean diastolic blood pressure reductions (P = 0.035): the hawthorn group showed greater reductions (baseline: 85.6 mmHg, 95% confidence interval [CI] = 83.3 to 87.8; outcome: 83.0 mmHg, 95% CI = 80.5 to 85.7) than the placebo group (baseline: 84.5 mmHg, 95% CI = 82 to 87; outcome: 85.0 mmHg, 95% CI = 82.2 to 87.8). There was no group difference in systolic blood pressure reduction from baseline (3.6 and 0.8 mmHg for hawthorn and placebo groups, respectively; P = 0.329). Although mean fat intake met current recommendations, mean sugar intake was higher and there were indications of potential multiple micronutrient deficiencies. No herb–drug interaction was found and minor health complaints were reduced from baseline in both groups. Conclusions This is the first randomised controlled trial to demonstrate a hypotensive effect of hawthorn in patients with diabetes taking medication. PMID:16762125

Hypotensive effects of hawthorn for patients with diabetes taking prescription drugs: a randomised controlled trial.

PubMed

Walker, Ann F; Marakis, Georgios; Simpson, Eleanor; Hope, Jessica L; Robinson, Paul A; Hassanein, Mohamed; Simpson, Hugh C R

2006-06-01

Hawthorn (Crataegus laevigata) leaves, flowers and berries are used by herbal practitioners in the UK to treat hypertension in conjunction with prescribed drugs. Small-scale human studies support this approach. To investigate the effects of hawthorn for hypertension in patients with type 2 diabetes taking prescribed drugs. Randomised controlled trial. General practices in Reading, UK. Patients with type 2 diabetes (n = 79) were randomised to daily 1200 mg hawthorn extract (n = 39) or placebo (n = 40) for 16 weeks. At baseline and outcome a wellbeing questionnaire was completed and blood pressure and fasting blood samples taken. A food frequency questionnaire estimated nutrient intake. Hypotensive drugs were used by 71% of the study population with a mean intake of 4.4 hypoglycaemic and/or hypotensive drugs. Fat intake was lower and sugar intake higher than recommendations, and low micronutrient intake was prevalent. There was a significant group difference in mean diastolic blood pressure reductions (P = 0.035): the hawthorn group showed greater reductions (baseline: 85.6 mmHg, 95% confidence interval [CI] = 83.3 to 87.8; outcome: 83.0 mmHg, 95% CI = 80.5 to 85.7) than the placebo group (baseline: 84.5 mmHg, 95% CI = 82 to 87; outcome: 85.0 mmHg, 95% CI = 82.2 to 87.8). There was no group difference in systolic blood pressure reduction from baseline (3.6 and 0.8 mmHg for hawthorn and placebo groups, respectively; P = 0.329). Although mean fat intake met current recommendations, mean sugar intake was higher and there were indications of potential multiple micronutrient deficiencies. No herb-drug interaction was found and minor health complaints were reduced from baseline in both groups. This is the first randomised controlled trial to demonstrate a hypotensive effect of hawthorn in patients with diabetes taking medication.

Resveratrol combined with total flavones of hawthorn alleviate the endothelial cells injury after coronary bypass graft surgery.

PubMed

Zhu, Ying; Feng, Bing; He, Songmin; Su, Zuqing; Zheng, Guangjuan

2018-02-01

To explore the preventive and therapeutic effects of Resveratrol combined with total flavones of hawthorn, compatibility of traditional Chinese medicines, on the endothelial cells injury after artery bypass graft surgery. The animal model of coronary artery bypass grafting (CABG) was prepared by transplanting a segment of autologous jugular vein onto the transected common carotid artery in rabbits. After CABG surgery, the rabbits were administrated with saline (model group), aspirin (Aspirin group), resveratrol (Res group), total flavones of hawthorn (Haw group) and resveratrol combined with total flavones of hawthorn (Res+Haw group) once a day for eight weeks, respectively. Eight weeks later, the grafting arteries from all group were obtained for the pathomorphism observation, peripheral blood was collected to detect circulating endothelial cells (CECs) by flow cytometry. And the concentration of albumen and mRNA of ICAM-1 in the serum were measured by western blot and quantitative real-time polymerase chain reaction, respectively. Compared with the model group, the level of CECs density and the expressions of albumen and mRNA of ICAM-1 were significantly decreased in the aspirin,resveratrol,total flavones of hawthorn and resveratrol combined with total flavones of hawthorn groups (P < .05). Of note, above all parameters were lower in Res group than aspirin group. The Resveratrol combined with total flavones of hawthorn could protect the endothelial cells after coronary artery bypass graft. Copyright © 2018 Elsevier GmbH. All rights reserved.

Generic Airspace Survey

NASA Technical Reports Server (NTRS)

Mogford, Richard H.; Bridges, Wayne; Gujarl, Vimmy; Lee, Paul U.; Preston, William

2013-01-01

This paper reports on an extension of generic airspace research to explore the amount of memorization and specialized skills required to manage sectors with specific characteristics or factors. Fifty-five retired controllers were given an electronic survey where they rated the amount of memorization or specialized skills needed for sixteen generic airspace factors. The results suggested similarities in the pattern of ratings between different areas of the US (East, Central, and West). The average of the ratings for each area also showed some differences between regions, with ratings being generally higher in the East area. All sixteen factors were rated as moderately to highly important and may be useful for future research on generic airspace, air traffic controller workload, etc.

Hazardous Waste Cleanup: Inmont Corporation in Hawthorne, New Jersey

EPA Pesticide Factsheets

The Inmont Corporation Hawthorne plant is a former manufacturing site located on approximately 16 acres in southeastern Passaic County, New Jersey. The facility is bordered by industrial properties and the Passaic River flows easterly along the southern

The investigation of some bioactive compounds and antioxidant properties of hawthorn (Crataegus monogyna subsp. monogyna Jacq)

PubMed Central

Keser, Serhat; Celik, Sait; Turkoglu, Semra; Yilmaz, Ökkes; Turkoglu, Ismail

2014-01-01

Aim: The antioxidant and pharmacological effects of hawthorn have mainly been attributed to the polyphenolic contents. The aim of this research is to determine some bioactive compounds and antioxidant properties of hawthorn aqueous and ethanol extracts of leaves, flowers, and ripened fruits. Materials and Methods: For this purpose, antioxidant activities of extracts were assessed on DPPH•, ABTS•+, superoxide scavenging, reducing power and ferrous metal chelating activity assays and phenolic content of extracts was determined by Folin—Cioacalteu’s reagent. Results: The flavonoids including rutin, apigenin, myricetin, quercetin, naringenin and kaempferol, were identified by high-performance liquid chromatography in the hawthorn extract. Conclusion: It was observed the aqueous and ethanol extracts of Crataegus monogyna subsp. monogyna fruits showed the highest activity in reducing power and metal chelating activity assays. In addition, it was determined that the aqueous flower extract showed higher flavonoid content than aqueous leaves extract. The antioxidant and pharmacological effects of hawthorn have mainly been attributed to the polyphenolic contents. PMID:26401347

The investigation of some bioactive compounds and antioxidant properties of hawthorn (Crataegus monogyna subsp. monogyna Jacq).

PubMed

Keser, Serhat; Celik, Sait; Turkoglu, Semra; Yilmaz, Ökkes; Turkoglu, Ismail

2014-01-01

The antioxidant and pharmacological effects of hawthorn have mainly been attributed to the polyphenolic contents. The aim of this research is to determine some bioactive compounds and antioxidant properties of hawthorn aqueous and ethanol extracts of leaves, flowers, and ripened fruits. For this purpose, antioxidant activities of extracts were assessed on DPPH•, ABTS•+, superoxide scavenging, reducing power and ferrous metal chelating activity assays and phenolic content of extracts was determined by Folin-Cioacalteu's reagent. The flavonoids including rutin, apigenin, myricetin, quercetin, naringenin and kaempferol, were identified by high-performance liquid chromatography in the hawthorn extract. It was observed the aqueous and ethanol extracts of Crataegus monogyna subsp. monogyna fruits showed the highest activity in reducing power and metal chelating activity assays. In addition, it was determined that the aqueous flower extract showed higher flavonoid content than aqueous leaves extract. The antioxidant and pharmacological effects of hawthorn have mainly been attributed to the polyphenolic contents.

Coalition Airspace Management and Deconfliction

DTIC Science & Technology

2008-01-01

and the Low- Cost Autonomous Attack System (LOCAAS). Current airspace management procedures are inadequate to deal with these types of weapons. As...drawn to this projection. 11 these spaces over a geocentric terrain removes both types of distortion and is inherently easier to understand, as...shown in Figure 8. Figure 8 - Airspaces on a Geocentric Projection - The corridor airspaces in this picture span large distances, yet on this

Organic acids, sugars, vitamin C content and some pomological characteristics of eleven hawthorn species (Crataegus spp.) from Turkey.

PubMed

Gundogdu, Muttalip; Ozrenk, Koray; Ercisli, Sezai; Kan, Tuncay; Kodad, Ossama; Hegedus, Attila

2014-05-30

The Hawthorn (Crateagus sp.) mostly occurs around the temperate region of the world with a high number of species, producing a fruit with numerous beneficial effects for human health. The aim of the study was to determine organic acid and sugar contents in the fruit of a number of hawthorn species grown in Erzincan province of Turkey. Citric acid was the predominant organic acid in all hawthorn species and C. pseudoheterophylla had the highest citric acid content (23.688 g/100 g). There were not statistically significant differences among hawthorn species (except C. atrosanguinea Pojark) in terms of fumaric acid content. C.pontica C.Koch had a higher content of vitamin C (9.418 mg/100 g) compared to other species. Fructose was the predominant sugar component in all species and C. monogyna subsp. monogyna Joiq had the highest fructose content (18.378 g/100 g). The high fruit quality of the studied species indicates the importance of this fruit in human nutrition as a natural source. The study revealed that there were differences in terms of fruit characteristics among hawthorn species and thus better quality hawthorn genotypes can be selected within the species. Hence, this study is considered to be a valuable reference for forthcoming studies. The high fruit quality of the studied species indicates the importance of this fruit in human nutrition as a natural source.

Identification of fruit volatiles from green hawthorn (Crataegus viridis) and blueberry hawthorn (Crataegus brachyacantha) host plants attractive to different phenotypes of Rhagoletis pomonella flies in the southern United States.

PubMed

Cha, Dong H; Powell, Thomas H Q; Feder, Jeffrey L; Linn, Charles E

2011-09-01

The apple maggot fly, Rhagoletis pomonella, infests several hawthorn species in the southern USA. In a companion paper, we showed that R. pomonella flies infesting two different mayhaw species (Crataegus opaca and C. aestivalis) can discriminate between volatile blends developed for each host fruit, and that these blends are different from previously constructed blends for northern fly populations that infest domestic apple (Malus domestica), downy hawthorn (Crataegus mollis), and flowering dogwood (Cornus florida). Here, we show by using coupled gas chromatography and electroantennographic detection (GC-EAD), gas chromatography with mass spectrometry (GC-MS), and flight tunnel bioassays, that two additional southern hawthorn fly populations infesting C. viridis (green hawthorn) and C. brachyacantha (blueberry hawthorn) also can discriminate between volatile blends for each host fruit type. A 9-component blend was developed for C. viridis (3-methylbutan-1-ol [5%], butyl butanoate [19.5%], propyl hexanoate [1.5%], butyl hexanoate [24%], hexyl butanoate [24%], pentyl hexanoate [2.5%], 1-octen-3-ol [0.5%], pentyl butanoate [2.5%], and (3E)-4,8-dimethyl-1,3,7-nonatriene (DMNT) [20.5%]) and an 8-component blend for C. brachyacantha (3-methylbutan-1-ol [0.6%], butyl acetate [50%], pentyl acetate [3.5%], butyl butanoate [9%], butyl hexanoate [16.8%], hexyl butanoate [16.8%], 1-octen-3-ol [0.3%], and pentyl butanoate [3%]). Crataegus viridis and C. brachyacantha-origin flies showed significantly higher levels of upwind oriented flight to their natal blend in flight tunnel assays compared to the alternate, non-natal blend and previously developed northern host plant blends. The presence of DMNT in C. viridis and butyl acetate in C. brachyacantha appeared to be largely responsible for driving the differential response. This sharp behavioral distinction underscores the diversity of odor response phenotypes in the southern USA, points to possible host race formation in these

Antioxidant and anti-inflammatory neolignans from the seeds of hawthorn.

PubMed

Peng, Ying; Lou, Li-Li; Liu, Si-Fan; Zhou, Le; Huang, Xiao-Xiao; Song, Shao-Jiang

2016-11-15

Seven new neolignans (1-2, 7-11) and five known compounds (3-6, 12) were isolated from the 70% EtOH extract of hawthorn seeds. Their structures were determined by spectroscopic analyses. The antioxidant and anti-inflammatory activities of all the isolates were investigated. Most of the isolates showed moderate radical scavenging activity in the DPPH assay and significant activities in the ABTS and FRAP assays. Furthermore, compounds 7-12 exhibited marked nitric oxide (NO) inhibition and compounds 1-4 had a potent necrosis factor-α (TNF-α) inhibitory effect. The results we obtained showed that hawthorn seeds can be regarded as a potential new and cheap source of antioxidants and inflammation inhibitors. Copyright © 2016 Elsevier Ltd. All rights reserved.

Ammonium carbonate is more attractive than apple and hawthorn fruit volatile lures to Rhagoletis pomonella (Diptera: Tephritidae) in Washington State.

PubMed

Yee, Wee L; Nash, Meralee J; Goughnour, Robert B; Cha, Dong H; Linn, Charles E; Feder, Jeffrey L

2014-08-01

The apple maggot fly, Rhagoletis pomonella (Walsh), is an introduced, quarantine pest of apple (Malus domestica Borkhausen) in the Pacific Northwest of the United States. In the eastern United States where the fly is native, fruit volatiles have been reported to be more attractive than ammonia compounds to R. pomonella. However, the opposite may be true in the western United States. Here, we determined whether newly identified western apple and western hawthorn fruit volatiles are more attractive than ammonium carbonate (AC) to R. pomonella in apple, black hawthorn, and ornamental hawthorn trees in western Washington State. In all three host trees, sticky red sphere or yellow panel traps baited with AC generally caught more flies than traps baited with lures containing the four newly developed fruit blends (modified eastern apple, western apple, western ornamental hawthorn, and western black hawthorn) or two older blends (eastern apple and eastern downy hawthorn). Fruit volatiles also displayed more variation among trapping studies conducted at different sites, in different host trees, and across years than AC. The results imply that traps baited with AC represent the best approach to monitoring R. pomonella in Washington State.

78 FR 7993 - Amendment of Class D and E Airspace; Tri-Cities, TN; Revocation of Class E Airspace; Tri-City, TN

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-05

... of Instrument Flight Rules (IFR) operations within the National Airspace System. This action also updates the geographic coordinates, airport name, and airspace designation. Also, this action corrects... controlled airspace within the National Airspace System. The FAA has determined that this regulation only...

Effects of hawthorn on the progression of heart failure in a rat model of aortic constriction.

PubMed

Hwang, Hyun Seok; Boluyt, Marvin O; Converso, Kimber; Russell, Mark W; Bleske, Barry E

2009-06-01

To determine the effects of hawthorn (Crataegus oxycantha) on left ventricular remodeling and function in pressure overload-induced heart failure in an animal model. Randomized, parallel, dose-ranging animal study. University research facility. Seventy-four male Sprague-Dawley rats; 44 were included in the final analysis. Rats underwent a sham operation or aortic constriction. Rats subjected to the sham operation were treated with vehicle (10% agar-agar), and those subjected to aortic constriction were treated with vehicle or hawthorn (C. oxycantha special extract WS 1442) 1.3, 13, or 130 mg/kg for 5 months. Rats and their hearts were weighed, and echocardiographic measurements were performed at baseline and at 2, 3, 4, and 5 months after aortic constriction. Protein expression for markers of fibrosis and for atrial natriuretic factor was also measured. Aortic constriction increased the left ventricular:body weight ratio by 53% in vehicle-treated rats; Hawthorn treatment did not significantly affect the aortic constriction-induced increase in this ratio. Left ventricular volumes and dimensions at systole and diastole significantly increased 5 months after aortic constriction compared with baseline in rats given vehicle (> 20% increase, p<0.05) but not in those given hawthorn 130 mg/kg (< 10% increase). After aortic constriction, the velocity of circumferential shortening significantly decreased in the vehicle group but not in the medium- or high-dose groups. In the aortic constriction-vehicle group, the induced increases in messenger RNA expression for atrial natriuretic factor (approximately 1000%) and fibronectin (approximately 80%) were significantly attenuated by high-dose hawthorn treatment by approximately 80% and 50%, respectively. Hawthorn treatment exhibited modest beneficial effects on cardiac remodeling and function during long-term, pressure overload-induced heart failure in rats.

Genetic relationships among some hawthorn (Crataegus spp.) species and genotypes.

PubMed

Yilmaz, Kadir Ugurtan; Yanar, Makbule; Ercisli, Sezai; Sahiner, Hatice; Taskin, Tuncer; Zengin, Yasar

2010-10-01

The genus Crataegus is well distributed in Turkey as a wild plant, with numerous, inherently variable species and genotypes. RAPD markers were used to study 17 hawthorn genotypes belonging to Crataegus monogyna ssp. monogyna Jacq (2 genotypes), C. monogyna ssp. azarella Jacq (1), Crataegus pontica K.Koch (3), Crataegus orientalis var. orientalis Pallas Ex Bieb (3), Crataegus pseudoheterophylla Pojark (1), Crataegus aronia var. dentata Browicz (1), C. aronia var. aronia Browicz (4), and Crateagus x bornmuelleri Zabel (2). The 10 RAPD primers produced 72 polymorphic bands (88% polymorphism). A dendrogram based on Jaccard's index included four major groups and one outgroup according to taxa. The lowest genetic variability was observed within C. aronia var. aronia genotypes. The study demonstrated that RAPD analysis is efficient for genotyping wild-grown hawthorns.

The Hawthorne effect in direct observation research with physicians and patients.

PubMed

Goodwin, Meredith A; Stange, Kurt C; Zyzanski, Stephen J; Crabtree, Benjamin F; Borawski, Elaine A; Flocke, Susan A

2017-12-01

This study examines the degree to which a "Hawthorne effect" alters outpatient-visit content. Trained research nurses directly observed 4454 visits to 138 family physicians. Multiple data sources were used to examine the Hawthorne effect including differences in medical record documentation for observed visits and the prior visit by the same patient, time use during visits on the first versus the second observation day of each physician, and report by the patient, physician, and observer of the effect of observation. Visits on the first versus the second observation day were longer by an average of 1 minute (P < .001); there were time-use differences for 4 of 20 behaviour categories evaluated. No effect of the observer on the interaction was reported by 74% of patients and 55% of physicians. Most of those that reported an affect indicated it was slight. Patients with non-White race, lower-educational level, and poorer health were more likely to report being affected by the observer. In a study that was designed to minimize the Hawthorne effect, the presence of an observer had little effect on most patient-physician visits but appeared to at least slightly effect a subgroup of vulnerable patients. © 2017 John Wiley & Sons, Ltd.

Acids, sugars, and sugar alcohols in Chinese hawthorn (Crataegus spp.) fruits.

PubMed

Liu, Pengzhan; Kallio, Heikki; Lü, Deguo; Zhou, Chuansheng; Ou, Shiyi; Yang, Baoru

2010-01-27

Acids, sugars, and sugar alcohols in the fruits of 22 cultivars/origins of three species of hawthorn (Crataegus spp.) were analyzed by gas chromatography and mass spectrometry. Citric acid (2.0-8.4 g/100 g dry mass [DM]), quinic acid (0.5-5.6 g/100 g DM), malic acid (0.3-1.1 g/100 g DM), fructose (5.5-18.4 g/100 g DM), glucose (5.3-16.6 g/100 g DM), sorbitol (3.0-15.7 g/100 g DM), and myo-inositol (0.1-0.3 g/100 g DM) were found in all the samples. Sucrose was present only in C. scabrifolia and three cultivars of C. pinnatifida var. major. C. scabrifolia differed from other species by its high content of quinic acid. The cultivars of C. pinnatifida var. major and C. brettschneideri had a higher content of total sugars and a higher sugar/acid ratio than the natural origins of C. pinnatifida and C. scabrifolia (P < 0.05). The hawthorn samples analyzed fell into two groups rich in sugars and acids respectively. This is the first report of the profiles of sugars and sugar alcohols and the occurrence of quinic acid in hawthorn fruits.

Effects of hawthorn on cardiac remodeling and left ventricular dysfunction after 1 month of pressure overload-induced cardiac hypertrophy in rats.

PubMed

Hwang, Hyun Seok; Bleske, Barry E; Ghannam, Michael M J; Converso, Kimber; Russell, Mark W; Hunter, James C; Boluyt, Marvin O

2008-02-01

Hawthorn (Crataegus) is a natural product used to treat patients with heart failure. The effects of hawthorn on cardiac remodeling, however, are not known. The purpose was to determine the effects of hawthorn treatment on remodeling and function of the left ventricle (LV) after 1 month of pressure overload-induced cardiac hypertrophy. Sprague-Dawley rats (male, 300 g) were subjected to sham operation (SH) or aortic constriction (AC) for 4 weeks and treated with Hawthorn (Crataegus-Extract- WS1442;1.3, 13, 130 mg kg(-1) day(-1); AC-L, AC-M, AC-H) or vehicle (SH-V, AC-V) for 3 weeks after surgery. Systolic and diastolic function were measured using echocardiographic assessment at baseline and 4 weeks after AC. AC increased the LV/body weight ratio by 34% in vehicle and hawthorn treated rats. Hawthorn markedly reduced LV chamber volumes (VOL) after AC [systolic VOL, mean +/- SEM, mm(3): SH-V, 87 +/- 13; AC-V, 93 +/- 12; AC-L, 62 +/- 9; AC-M, 68 +/- 12; AC-H; 50 +/- 11 and diastolic VOL: SH-V, 433 +/- 45; AC-V, 412 +/- 57; AC-L, 313 +/- 25; AC-M, 319 +/- 37; AC-H, 264 +/- 25 (p < 0.05)] and augmented relative wall thickness, mm: SH-V, 0.45 +/- 0.02; AC-V, 0.65 +/- 0.05; AC-L, 0.71 +/- 0.03; AC-M, 0.74 +/- 0.06; AC-H, 0.80 +/- 0.09 (p < 0.05). AC reduced velocity of circumferential shortening (Vcf(c)) by 28% compared with SH-V. Hawthorn attenuated the AC-induced decrease in Vcf(c) (p < 0.05). Hawthorn treatment modifies left ventricular remodeling and counteracts myocardial dysfunction in early pressure overload-induced cardiac hypertrophy.

Hawthorn extract inhibits human isolated neutrophil functions.

PubMed

Dalli, Ernesto; Milara, Javier; Cortijo, Julio; Morcillo, Esteban J; Cosín-Sales, Juan; Sotillo, José Francisco

2008-06-01

Hawthorn extract is a popular herbal medicine given as adjunctive treatment for chronic heart failure. In contrast to the cardiac properties of hawthorn extract, its anti-inflammatory effect has been scarcely investigated. This study examines the effects of a dry extract of leaves and flowers of Crataegus laevigata on various functional outputs of human neutrophils in vitro. Incubation of human neutrophils obtained from peripheral blood of healthy donors with C. laevigata extract (0.75-250 microg/ml) inhibited N-formyl-Met-Leu-Phe (FMLP)-induced superoxide anion generation, elastase release and chemotactic migration with potency values of 43.6, 21.9, and 31.6 microg/ml, respectively. By contrast, serum-opsonized zymosan-induced phagocytosis was unaltered by plant extract. C. laevigata extract (125 microg/ml) reduced FMLP-induced leukotriene B(4) production and lipopolysaccharide-induced generation of tumour necrosis factor-alpha and interleukin-8. Extract inhibited FMLP-induced intracellular calcium signal with potency of 17.4 microg/ml. Extract also markedly inhibited the extracellular calcium entry into calcium-depleted neutrophils, and the thapsigargin-induced intracellular calcium response. In conclusion, C. laevigata extract inhibited various functional outputs of activated human neutrophils which may be relevant to the pathophysiology of cardiac failure.

Common Methodology for Efficient Airspace Operations

NASA Technical Reports Server (NTRS)

Sridhar, Banavar

2012-01-01

Topics include: a) Developing a common methodology to model and avoid disturbances affecting airspace. b) Integrated contrails and emission models to a national level airspace simulation. c) Developed capability to visualize, evaluate technology and alternate operational concepts and provide inputs for policy-analysis tools to reduce the impact of aviation on the environment. d) Collaborating with Volpe Research Center, NOAA and DLR to leverage expertise and tools in aircraft emissions and weather/climate modeling. Airspace operations is a trade-off balancing safety, capacity, efficiency and environmental considerations. Ideal flight: Unimpeded wind optimal route with optimal climb and descent. Operations degraded due to reduction in airport and airspace capacity caused by inefficient procedures and disturbances.

Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial.

PubMed

Asher, Gary N; Viera, Anthony J; Weaver, Mark A; Dominik, Rosalie; Caughey, Melissa; Hinderliter, Alan L

2012-03-29

Hawthorn extract has been used for cardiovascular diseases for centuries. Recent trials have demonstrated its efficacy for the treatment of heart failure, and the results of several small trials suggest it may lower blood pressure. However, there is little published evidence to guide its dosing. The blood pressure lowering effect of hawthorn has been linked to nitric oxide-mediated vasodilation. The aim of this study was to investigate the relationship between hawthorn extract dose and brachial artery flow mediated dilation (FMD), an indirect measure of nitric oxide release. We used a four-period cross-over design to evaluate brachial artery FMD in response to placebo or hawthorn extract (standardized to 50 mg oligomeric procyanidin per 250 mg extract). Randomly sequenced doses of hawthorn extract (1000 mg, 1500 mg, and 2500 mg) and placebo were assigned to each participant. Doses were taken twice daily for 3 1/2 days followed by FMD and a 4-day washout before proceeding to the next dosing period. Twenty-one prehypertensive or mildly hypertensive adults completed the study. There was no evidence of a dose-response effect for our main outcome (FMD percent) or any of our secondary outcomes (absolute change in brachial artery diameter and blood pressure). Most participants indicated that if given evidence that hawthorn could lower their blood pressure, they would be likely to use it either in conjunction with or instead of lifestyle modification or anti-hypertensive medications. We found no evidence of a dose-response effect of hawthorn extract on FMD. If hawthorn has a blood pressure lowering effect, it is likely to be mediated via an NO-independent mechanism. This trial has been registered with ClinicalTrials.gov, a service of the U.S. National Institutes of Health: NCT01331486.

Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial

PubMed Central

2012-01-01

Background Hawthorn extract has been used for cardiovascular diseases for centuries. Recent trials have demonstrated its efficacy for the treatment of heart failure, and the results of several small trials suggest it may lower blood pressure. However, there is little published evidence to guide its dosing. The blood pressure lowering effect of hawthorn has been linked to nitric oxide-mediated vasodilation. The aim of this study was to investigate the relationship between hawthorn extract dose and brachial artery flow mediated dilation (FMD), an indirect measure of nitric oxide release. Methods We used a four-period cross-over design to evaluate brachial artery FMD in response to placebo or hawthorn extract (standardized to 50 mg oligomeric procyanidin per 250 mg extract). Randomly sequenced doses of hawthorn extract (1000 mg, 1500 mg, and 2500 mg) and placebo were assigned to each participant. Doses were taken twice daily for 3 1/2 days followed by FMD and a 4-day washout before proceeding to the next dosing period. Results Twenty-one prehypertensive or mildly hypertensive adults completed the study. There was no evidence of a dose-response effect for our main outcome (FMD percent) or any of our secondary outcomes (absolute change in brachial artery diameter and blood pressure). Most participants indicated that if given evidence that hawthorn could lower their blood pressure, they would be likely to use it either in conjunction with or instead of lifestyle modification or anti-hypertensive medications. Conclusion We found no evidence of a dose-response effect of hawthorn extract on FMD. If hawthorn has a blood pressure lowering effect, it is likely to be mediated via an NO-independent mechanism. Trial Registration This trial has been registered with ClinicalTrials.gov, a service of the U.S. National Institutes of Health: NCT01331486. PMID:22458601

76 FR 40598 - Establishment of Class E Airspace; Campbellton, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-11

...-1053; Airspace Docket No. 10-ASW-15] Establishment of Class E Airspace; Campbellton, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E airspace... proposed rulemaking to establish Class E airspace for Campbellton, TX, creating controlled airspace at 74...

76 FR 43822 - Establishment of Class E Airspace; Hearne, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-22

...-0214; Airspace Docket No. 11-ASW-2] Establishment of Class E Airspace; Hearne, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E airspace... notice of proposed rulemaking to establish Class E airspace for Hearne, TX, creating controlled airspace...

78 FR 65554 - Establishment of Class E Airspace; Rome, OR

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-01

...-0533; Airspace Docket No. 13-ANM-19] Establishment of Class E Airspace; Rome, OR AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E airspace... (NBAA) supporting the establishment of Class E en route airspace. Class E airspace designations are...

77 FR 56761 - Amendment of Class E Airspace; Kerrville, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-14

...-1399; Airspace Docket No. 11-ASW-14] Amendment of Class E Airspace; Kerrville, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at... Class E airspace for the Kerrville, TX, area, creating additional controlled airspace at Kerrville...

Integration into Civil Airspace Airworthiness and Safety

DTIC Science & Technology

2003-09-02

Integration into Civil Airspace Airworthiness and Safety 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER......into civil airspace lPurpose : n to explore and propose French process and means for integrating UAV into civil airspace. lMethod based on : n first

75 FR 68415 - Amendment of Class E Airspace; Kennett, MO

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-08

...; Airspace Docket No. 10-ACE-8] Amendment of Class E Airspace; Kennett, MO AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for Kennett, MO... rulemaking to amend Class E airspace for Kennett, MO, reconfiguring controlled airspace at Kennett Memorial...

76 FR 40597 - Amendment of Class E Airspace; Madison, SD

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-11

...-0135; Airspace Docket No. 11-AGL-4] Amendment of Class E Airspace; Madison, SD AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for Madison, SD, to... rulemaking to amend Class E airspace for Madison, SD, creating controlled airspace at Madison Municipal...

77 FR 46284 - Amendment of Class E Airspace; Lemmon, SD

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-03

...-0391; Airspace Docket No. 12-AGL-2] Amendment of Class E Airspace; Lemmon, SD AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at Lemmon, SD... rulemaking (NPRM) to amend Class E airspace for the Lemmon, SD, area, creating additional controlled airspace...

76 FR 44254 - Amendment of Class D Airspace; Denton, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-25

...-1327; Airspace Docket No. 10-ASW-19] Amendment of Class D Airspace; Denton, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class D airspace for Denton, TX, to... rulemaking to amend Class D airspace for Denton, TX, creating additional controlled airspace at Denton...

75 FR 18047 - Amendment of Class D Airspace; Hollywood, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-09

...; Airspace Docket No. 10-ASO-17] Amendment of Class D Airspace; Hollywood, FL AGENCY: Federal Aviation... rule published in the Federal Register on July 23, 1997, amending Class D airspace at North Perry... airspace area exclusion as Class D airspace area. This action corrects that error. The FAAs National...

76 FR 9219 - Amendment of Class E Airspace; Muncie, IN

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-17

...-1032; Airspace Docket No. 10-AGL-20] Amendment of Class E Airspace; Muncie, IN AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at Muncie, IN, to... proposed rulemaking to amend Class E airspace for Muncie, IN, creating controlled airspace at Ball Memorial...

Is the Hawthorne Effect in Educational Experiments a Chimera?

ERIC Educational Resources Information Center

Bauernfeind, Robert H.; Olson, Carl J.

1973-01-01

Reports on an experimental study designed to investigate the relationship between two factors commonly regarded as components of the Hawthorne Effect on pupil performance and on intellectual task. These factors are (1) direct cue, or awareness of experimentation, as represented by an announcement that pupils were the subjects of an experiment; and…

78 FR 63868 - Amendment of Restricted Area R-2515; Muroc Lake, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-25

...-0802; Airspace Docket No. 13-AWP-7] RIN 2120-AA66 Amendment of Restricted Area R-2515; Muroc Lake, CA... using agency name for Restricted Area R-2515 Muroc Lake, CA, to read ``Commander, 412th Test Wing (412... using agency name for Restricted Area R-2515 Muroc Lake, CA, from ``Commander Air Force Flight Test...

Energy Engineering Analysis Program, energy survey of Army Industrial Facilities, Western Area Demilitarization Facility Hawthorne Ermy Ammunition Plant Hawthorne, Nevada. Volume 1. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-03-17

This report summarizes all work for the Energy Survey of Army Industrial Facilities, Energy Engineering Analysis Program (EEAP) at the Western Area Demilitarization Facility (WADF) of the Hawthorne Army Ammunition Plant (HWAAP), Hawthorne, Nevada, authorized under Contract No. DACA03-92-C-0155 with the U.S. Army Corps of Engineers, Sacramento District, California. The purpose of this energy survey is to develop a set of projects and actions that will reduce energy consumption and operating costs of selected facilities at the WADF. A preliminary inspection of facilities at WADF by Keller Gannon that identified potential retrofit opportunities was submitted as the EEAP Study andmore » Criteria Review in December 1993. This document formed the basis of the Detailed Scope of Work for this study. Facilities included in the survey and study, together with operational status, are listed in Table 1 - 1. The complete scope of work appears in Appendix.« less

78 FR 52109 - Proposed Amendment of Class D and E Airspace, and Establishment of Class E Airspace; Salisbury, MD

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-22

...]30'34'' W.) That airspace extending upward from the surface within 2.5 miles each side of a 133[deg...-Ocean City Wicomico Regional Airport, MD (Lat. 38[deg]20'25'' N., long. 75[deg]30'34'' W.) That airspace... (Lat. 38[deg]20'25'' N., long. 75[deg]30'34'' W.) That airspace extending upward from the surface...

Energy Engineering Analysis Program, energy survey of Army Industrial Facilities, Western Area Demilitarization Facility, Hawthorne Army Ammunition Plant, Hawthorne, Nevada; Volume 1 - energy report. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-03-17

This report summarizes all work for the Energy Survey of Army Industrial Facilities, Energy Engineering Analysis Program (EEAP) at the Western Area Demilitarization Facility (WADF) of the Hawthorne Army Ammunition Plant (HWAAP), Hawthorne, Nevada, authorized under Contract No. DACA05-92-C-0155 with the U.S. Army Corps of Engineers, Sacramento District, California. The purpose of this energy survey is to develop a set of projects and actions that will reduce energy consumption and operating costs of selected facilities at the WADF. A preliminary inspection of facilities at WADF by Keller Gannon that identified potential retrofit opportunities was submitted as the EEAP Study andmore » Criteria Review in December 1993. This document formed the basis of the Detailed Scope of Work for this study. Facilities included in the survey and study, together with operational status.« less

A comparison of the effects of commercially available hawthorn preparations on calcium transients of isolated cardiomyocytes.

PubMed

Rodriguez, Michelle E; Poindexter, Brian J; Bick, Roger J; Dasgupta, Amitava

2008-12-01

We studied the potential cardiac effects of two alcohol extracts of commercially available hawthorn using rat cardiomyocytes and measuring calcium transients by real-time fluorescence spectrophotometry. One preparation was a blend of hawthorn flowers, leaves, and berries (extract #1), and the other (extract #2) was from a "berries-only" preparation. Fluorescent images and calcium transients were acquired concurrently. Addition of extract #1 resulted in the initiation of robust calcium transients and eventual calcium overload, while addition of extract #2 caused increased calcium sparking, initiation of calcium transients, and an increased beating rate but no calcium overload. To identify the mechanisms of increased calcium influx, adult rat cardiomyocytes were challenged with 10 microM ouabain, a Na(+),K(+)-ATPase inhibitor, and the calcium channel blocker nifedipine. The findings revealed that equal volumes of the two readily available hawthorn preparations demonstrated markedly different effects on isolated adult rat cardiomyocytes, suggesting important implications for patients who are using these preparations to supplement or even replace their prescribed cardiac medications as to which preparation(s) to use, and potential dire consequences, particularly in cardiac patients. Our study indicates that the mechanism of cardiac activity of hawthorn is via the Na(+),K(+)-ATPase and intracellular calcium concentrations are influenced.

Abundances of apple maggot, Rhagoletis pomonella, across different areas in central Washington, with special reference to black-fruited hawthorns

USDA-ARS?s Scientific Manuscript database

The apple maggot fly, Rhagoletis pomonella (Walsh), has infested native black-fruited hawthorn (mostly Crataegus douglasii Lindl.) in central Washington since at least 2003, but little is known about the fly’s ecology in hawthorns there. The main objective here was to determine adult and larval abu...

75 FR 17561 - Amendment to Restricted Area R-2510A; El Centro, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-07

...-0346; Airspace Docket No. 10-AWP-3] RIN 2120-AA66 Amendment to Restricted Area R-2510A; El Centro, CA... Restricted Area R-2510A, El Centro, CA. Specifically, the action inadvertently omitted the reference to.... 92-AWP-15 entitled ``Alteration and Subdivision of Restricted Area R-2510A; El Centro, CA''. That...

Effects of pretreatments on anthocyanin composition, phenolics contents and antioxidant capacities during fermentation of hawthorn (Crataegus pinnatifida) drink.

PubMed

Liu, Suwen; Chang, Xuedong; Liu, Xiufeng; Shen, Zhanwei

2016-12-01

The effect of microwave and heat pretreatment on the content and composition of anthocyanins, phenolics, and the antioxidant capacity of hawthorn drink were studied. Nine anthocyanins were isolated by chromatographic separation from the Zirou hawthorn source and their structure identified using HPLC-DAD-ESI/MS analysis. Heat and microwave pretreatments had a significant impact on the relative contents of hawthorn anthocyanins, such as cyanidin-3-galactoside (82.9% and 76.9%, respectively) and cyanidin-3-glucoside (9.2% and 11.5%, respectively). Pretreatment had no significant effect on pH, total soluble solid or total acid. More anthocyanins remained after heat treatment than after microwaving (0.745mg/100mL), and were 52.4% higher than the control group after storage for 7days. The colour density of the heat treated group was higher than the control group (24.5%) after 12days of fermentation. The main antioxidant capacities of the hawthorn drinks came from total polyphenolics rather than total anthocyanins or total flavonoids. Copyright © 2016 Elsevier Ltd. All rights reserved.

Changes in physicochemical characteristics and free amino acids of hawthorn (Crataegus pinnatifida) fruits during maturation.

PubMed

Li, Wei-Qin; Hu, Qing-Ping; Xu, Jian-Guo

2015-05-15

In this study, changes in physicochemical characteristics associated with fruit quality and free amino acids were investigated during maturation of hawthorn fruits. Significant differences in these parameters were found during maturation. The color turned progressively from mature green to semi-red, to reach bright red; the shape changed gradually from oval to round or approached round; the size, weight, and edible part (flesh/core ratio) of hawthorns increased while the density of intact fruits did not change. The content of moisture, total soluble sugars, soluble pectin, reduced ascorbic acid, total ascorbic acid, fructose, and sucrose increased while crude protein content decreased significantly. The levels of starch, sucrose, titratable acidity, protopectin, pectin, total free amino acids, and total essential amino acids initially increased and then decreased gradually during maturation. The outcomes of this study provide additional and useful information for fresh consumption and processing as well as utilization of dropped unripe hawthorn fruits. Copyright © 2014 Elsevier Ltd. All rights reserved.

75 FR 11475 - Establishment of Class D Airspace, Modification of Class E Airspace; Columbus, GA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-11

... Army Airfield, Columbus, GA, would be removed from the Class E2 and E5 airspace description, and would.... * * * * * ASO GA E5 Columbus, GA [Amended] Columbus Metropolitan Airport, GA (Lat. 32[deg]30'59'' N., long. 84... Airspace; Columbus, GA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed...

Comparing Methods for Dynamic Airspace Configuration

NASA Technical Reports Server (NTRS)

Zelinski, Shannon; Lai, Chok Fung

2011-01-01

This paper compares airspace design solutions for dynamically reconfiguring airspace in response to nominal daily traffic volume fluctuation. Airspace designs from seven algorithmic methods and a representation of current day operations in Kansas City Center were simulated with two times today's demand traffic. A three-configuration scenario was used to represent current day operations. Algorithms used projected unimpeded flight tracks to design initial 24-hour plans to switch between three configurations at predetermined reconfiguration times. At each reconfiguration time, algorithms used updated projected flight tracks to update the subsequent planned configurations. Compared to the baseline, most airspace design methods reduced delay and increased reconfiguration complexity, with similar traffic pattern complexity results. Design updates enabled several methods to as much as half the delay from their original designs. Freeform design methods reduced delay and increased reconfiguration complexity the most.

75 FR 31677 - Amendment of Class E Airspace; Corpus Christi, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-04

...-0089; Airspace Docket No. 10-ASW-1] Amendment of Class E Airspace; Corpus Christi, TX AGENCY: Federal... the Corpus Christi, TX area. Additional controlled airspace is necessary to accommodate new Standard... E airspace for the Corpus Christi, TX area, reconfiguring controlled airspace at Aransas County...

The comparison of anti-oxidative kinetics in vitro of the fluid extract from maidenhair tree, motherwort and hawthorn.

PubMed

Bernatoniene, Jurga; Kucinskaite, Agne; Masteikova, Ruta; Kalveniene, Zenona; Kasparaviciene, Giedre; Savickas, Arunas

2009-01-01

The aim of the study was to perform a quantitative analysis of fluid extracts of maidenhair tree (Ginkgo biloba L.), motherwort (Leonurus cardiaca L.) and hawthorn (Crataegus monogyna Jacq.), to evaluate their antioxidant activity and to compare their ability to inactivate free radicals. The antioxidant activity was measured using the DPPH*and the ABTS*+ radical scavenging reaction systems. The study showed that the manifestation of the radical scavenging capacity in the DPPH* reaction system was in the following order: the fluid extract of hawthorn (70.37 +/- 0.80%) > the fluid extract of maidenhair tree (82.63 +/- 0.23%) > the fluid extract of motherwort (84.89 +/- 0.18%), while in the ABTS*+ reaction system, the manifestation of the radical scavenging capacity was in the following order: the fluid extract of hawthorn (87.09 +/- 0.55%) > the fluid extract of motherwort (88.28 +/- 1.06%) > the fluid extract of maidenhair tree (88.39 +/- 0.72%). The results showed that in the DPPH* reaction system, fluid extract of motherwort manifested higher antioxidant activity, compared to the fluid extracts of maidenhair tree and hawthorn. By contrast, in the ABTS*+ reaction system, higher antioxidant activity was found in the fluid extract of maidenhair tree, compared to the fluid extracts of motherwort and hawthorn. This would suggest that preparations manufactured from these herbal raw materials could be used as effective preventive means and valuable additional remedies in the treatment of diseases caused by oxidative stress.

75 FR 28756 - Amendment of Restricted Area R-2502A; Fort Irwin, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-24

...-0471; Airspace Docket No. 10-AWP-7] RIN 2120-AA66 Amendment of Restricted Area R-2502A; Fort Irwin, CA... controlling agency of Restricted Area R-2502A, Fort Irwin, CA, from ``FAA, Hi-Desert TRACON, Edwards, CA'' to... Regulations (14 CFR) part 73 by changing the controlling agency for R-2502A from ``FAA, Hi- Desert TRACON...

77 FR 4459 - Amendment of Class E Airspace; Greenfield, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-30

...-0846; Airspace Docket No. 11-ACE-18] Amendment of Class E Airspace; Greenfield, IA AGENCY: Federal... Greenfield, IA. Decommissioning of the Greenfield non-directional beacon (NDB) at Greenfield Municipal... rulemaking to amend Class E airspace for Greenfield, IA, reconfiguring controlled airspace at Greenfield...

76 FR 43610 - Proposed Amendment of Class E Airspace; Spearfish, SD

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-21

...-0431; Airspace Docket No. 11-AGL-11] Proposed Amendment of Class E Airspace; Spearfish, SD AGENCY... action proposes to amend Class E airspace at Spearfish, SD. Additional controlled airspace is necessary... instrument approach procedures at Black Hills Airport-Clyde Ice Field, Spearfish, SD. Controlled airspace is...

76 FR 43612 - Proposed Amendment of Class E Airspace; Sturgis, SD

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-21

...-0430; Airspace Docket No. 11-AGL-10] Proposed Amendment of Class E Airspace; Sturgis, SD AGENCY... action proposes to amend Class E airspace at Sturgis, SD. Additional controlled airspace is necessary to... instrument approach procedures at Sturgis Municipal Airport, Sturgis, SD. Controlled airspace is needed for...

Hypolipidemic and cardioprotective benefits of a novel fireberry hawthorn fruit extract in the JCR:LA-cp rodent model of dyslipidemia and cardiac dysfunction.

PubMed

Diane, Abdoulaye; Borthwick, Faye; Wu, Sheng; Lee, Jeanette; Brown, Paula N; Dickinson, Timothy A; Croft, Kevin D; Vine, Donna F; Proctor, Spencer D

2016-09-14

Hawthorn is a widely used herbal alternative medicine for the treatment of various cardiovascular diseases. However, the attributed health benefits, purported to be due to the presence of phenolic compounds, may depend on both the specific species and plant part. Studies to date investigating effects of hawthorn on heart disease(s) have used well-described European and/or Asian species, while little is known regarding the bioactivity of species native to North America. Six weeks of supplementation of both fireberry hawthorn berry (native Crataegus chrysocarpa) and English hawthorn leaf (C. monogyna, naturalized in North America) in the JCR:LA-cp rat, resulted in a significant reduction in heart weight, fasting LDL-C and improved heart function (p < 0.05). Fasting triglyceride and myocardial fibrosis were also reduced, but only by the berry extract. We demonstrate that both of the Canadian-sourced hawthorn extracts (introduced leaf and native berry) have cardioprotective benefits, likely via increased availability of nitric oxide.

78 FR 48298 - Amendment of Class E Airspace; Commerce, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-08

...-0269; Airspace Docket No. 13-ASW-3] Amendment of Class E Airspace; Commerce, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at Commerce, TX. Additional controlled airspace is necessary to accommodate new Area Navigation (RNAV...

76 FR 67058 - Amendment of Class E Airspace; Sturgis, SD

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-31

...-0430; Airspace Docket No. 11-AGL-10] Amendment of Class E Airspace; Sturgis, SD AGENCY: Federal... Sturgis, SD, to accommodate new Area Navigation (RNAV) Standard Instrument Approach Procedures at Sturgis... proposed rulemaking to amend Class E airspace for Sturgis, SD, creating controlled airspace at Sturgis...

Validation of the Antidiabetic and Hypolipidemic Effects of Hawthorn by Assessment of Gluconeogenesis and Lipogenesis Related Genes and AMP-Activated Protein Kinase Phosphorylation.

PubMed

Shih, Chun-Ching; Lin, Cheng-Hsiu; Lin, Yih-Jiun; Wu, Jin-Bin

2013-01-01

Since with the increased use of antidiabetic and antihyperlipidemic effect of phytonutrients for daily supplement has gained considerable attention worldwide, we examine the effect and molecular mechanism of Crataegus pinnatifida Bge. var. major N.E. Br. (hawthorn) by quantifying the expression of hepatic gluconeogenesis and lipogenesis on diabetes and dyslipidemia in high-fat (HF)-fed C57BL/6J mice. Firstly, mice were divided randomly into two groups: the control (CON) group was fed with a low-fat diet, whereas the experimental group was fed a 45% HF diet for 8 weeks. Afterwards, the CON group was treated with vehicle, whereas the HF group was subdivided into five groups and was given orally hawthorn extract (including 0.2, 0.5, 1.0 g/kg/day extracts) or rosiglitazone (Rosi) or vehicle for 4 weeks afterward. Diabetic mice showed an increase in plasma glucose and insulin. Glucose lowering was comparable with Rosi-treated mice. This study demonstrated that hawthorn was effective in ameliorating the HF diet-induced hyperglycemia, hypertriglyceridemia and hypercholesterolaemia. Hawthorn extract significantly increases the hepatic protein contents of AMP-activated protein kinase (AMPK) phosphorylation and reduces expression of phosphenol pyruvate carboxykinase (PEPCK) and glucose production. Furthermore, hawthorn decreased in hepatic triacylglycerol and cholesterol synthesis (including sterol regulatory element binding protein-1c (SREBP-1c), fatty acid synthase (FAS), SREBP2). An increase in expressions of apoA-I gene and high-density lipoprotein cholesterol (HDL-C) was detected in HF-fed mice treated with high dose hawthorn. Our data suggest that hawthorn extract are capable of decreasing glucose production and triacylglycerol synthesis by inducing AMPK-phosphorylation and hawthorn is a candidate source of antidiabetic and antihyperlipidemic phytonutrients factors.

Validation of the Antidiabetic and Hypolipidemic Effects of Hawthorn by Assessment of Gluconeogenesis and Lipogenesis Related Genes and AMP-Activated Protein Kinase Phosphorylation

PubMed Central

Shih, Chun-Ching; Lin, Cheng-Hsiu; Lin, Yih-Jiun; Wu, Jin-Bin

2013-01-01

Since with the increased use of antidiabetic and antihyperlipidemic effect of phytonutrients for daily supplement has gained considerable attention worldwide, we examine the effect and molecular mechanism of Crataegus pinnatifida Bge. var. major N.E. Br. (hawthorn) by quantifying the expression of hepatic gluconeogenesis and lipogenesis on diabetes and dyslipidemia in high-fat (HF)-fed C57BL/6J mice. Firstly, mice were divided randomly into two groups: the control (CON) group was fed with a low-fat diet, whereas the experimental group was fed a 45% HF diet for 8 weeks. Afterwards, the CON group was treated with vehicle, whereas the HF group was subdivided into five groups and was given orally hawthorn extract (including 0.2, 0.5, 1.0 g/kg/day extracts) or rosiglitazone (Rosi) or vehicle for 4 weeks afterward. Diabetic mice showed an increase in plasma glucose and insulin. Glucose lowering was comparable with Rosi-treated mice. This study demonstrated that hawthorn was effective in ameliorating the HF diet-induced hyperglycemia, hypertriglyceridemia and hypercholesterolaemia. Hawthorn extract significantly increases the hepatic protein contents of AMP-activated protein kinase (AMPK) phosphorylation and reduces expression of phosphenol pyruvate carboxykinase (PEPCK) and glucose production. Furthermore, hawthorn decreased in hepatic triacylglycerol and cholesterol synthesis (including sterol regulatory element binding protein-1c (SREBP-1c), fatty acid synthase (FAS), SREBP2). An increase in expressions of apoA-I gene and high-density lipoprotein cholesterol (HDL-C) was detected in HF-fed mice treated with high dose hawthorn. Our data suggest that hawthorn extract are capable of decreasing glucose production and triacylglycerol synthesis by inducing AMPK-phosphorylation and hawthorn is a candidate source of antidiabetic and antihyperlipidemic phytonutrients factors. PMID:23690849

77 FR 29920 - Proposed Amendment of Class E Airspace; Lemmon, SD

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-21

...-0391; Airspace Docket No. 12-AGL-2] Proposed Amendment of Class E Airspace; Lemmon, SD AGENCY: Federal... proposes to amend Class E airspace at Lemmon, SD. Additional controlled airspace is necessary to... Municipal Airport, Lemmon, SD. Controlled airspace is needed for the safety and management of IFR operations...

75 FR 63708 - Establishment of Class E Airspace; Kalaupapa, HI

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-18

...-0650; Airspace Docket No. 10-AWP-9] Establishment of Class E Airspace; Kalaupapa, HI AGENCY: Federal... airspace at Kalaupapa, HI, to accommodate aircraft using a new Area Navigation (RNAV) Global Positioning... Register a notice of proposed rulemaking to establish controlled airspace at Kalaupapa, HI (75 FR 49868...

76 FR 18041 - Establishment of Class E Airspace; Kahului, HI

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-01

...-1233; Airspace Docket No. 10-AWP-21] Establishment of Class E Airspace; Kahului, HI AGENCY: Federal... airspace at Kahului Airport, Kahului, HI, to accommodate aircraft using Area Navigation (RNAV) standard... establish controlled airspace at Kahului, HI (76 FR 3571). Interested parties were invited to participate in...

75 FR 37291 - Amendment of Class E Airspace; Osceola, AR

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-29

...-1183; Airspace Docket No. 09-ASW-38] Amendment of Class E Airspace; Osceola, AR AGENCY: Federal... Osceola, AR. Decommissioning of the Osceola non-directional beacon (NDB) at Osceola Municipal Airport has... rulemaking to amend Class E airspace for Osceola, AR, reconfiguring controlled airspace at Osceola Municipal...

78 FR 48302 - Establishment of Class E Airspace; Wagner, SD

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-08

...-0004; Airspace Docket No. 13-AGL-1] Establishment of Class E Airspace; Wagner, SD AGENCY: Federal... at Wagner, SD. Controlled airspace is necessary to accommodate new Area Navigation (RNAV) Standard... Federal Register a notice of proposed rulemaking (NPRM) to establish Class E airspace for the Wagner, SD...

78 FR 41685 - Amendment of Class E Airspace; Worthington, MN

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-11

...-1139; Airspace Docket No. 12-AGL-12] Amendment of Class E Airspace; Worthington, MN AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at... rulemaking (NPRM) to amend Class E airspace for the Worthington, MN, area, creating additional controlled...

76 FR 43821 - Establishment of Class E Airspace; Ranger, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-22

...-1240; Airspace Docket No. 10-ASW-18] Establishment of Class E Airspace; Ranger, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E airspace... Register a notice of proposed rulemaking to establish Class E airspace for Ranger, TX, creating controlled...

75 FR 13668 - Amendment of Class E Airspace; Georgetown, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-23

...-0934; Airspace Docket No. 09-ASW-29] Amendment of Class E Airspace; Georgetown, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at... Register a notice of proposed rulemaking to amend Class E airspace for Georgetown Municipal Airport...

76 FR 16530 - Establishment of Class E Airspace; Creighton, NE

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-24

...-1170; Airspace Docket No. 10-ACE-13] Establishment of Class E Airspace; Creighton, NE AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E airspace... Federal Register a notice of proposed rulemaking to establish Class E airspace for Creighton, NE, creating...

76 FR 47061 - Amendment of Class E Airspace; Lakeland, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-04

...-0005; Airspace Docket No. 10-ASO-42] Amendment of Class E Airspace; Lakeland, FL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at... proposed rulemaking (NPRM) to amend Class E airspace at Lakeland Linder Regional Airport, Lakeland, FL (75...

76 FR 80232 - Establishment of Class E Airspace; Oneonta, AL

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-23

...-0744; Airspace Docket No. 11-ASO-33] Establishment of Class E Airspace; Oneonta, AL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E Airspace... published in the Federal Register a notice of proposed rulemaking (NPRM) to establish Class E airspace at...

78 FR 11980 - Amendment of Class E Airspace; Casper, WY

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-21

...-0509; Airspace Docket No. 12-ANM-15] Amendment of Class E Airspace; Casper, WY AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace areas at Casper... were received. Class E airspace designations are published in paragraphs 6004, 6005 and 6006...

75 FR 65225 - Amendment of Class E Airspace; Youngstown, OH

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-22

...-267; Airspace Docket No. 10-AGL-5] Amendment of Class E Airspace; Youngstown, OH AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for... Federal Register a notice of proposed rulemaking to amend Class E airspace for Youngstown, OH, creating...

78 FR 54413 - Proposed Establishment of Class E Airspace; Star, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-04

...-0440; Airspace Docket No. 13-ASO-10] Proposed Establishment of Class E Airspace; Star, NC AGENCY... action proposes to establish Class E Airspace at Star, NC, to accommodate a new Area Navigation (RNAV... establish Class E airspace at Star, NC, providing the controlled airspace required to support the new RNAV...

14 CFR 71.33 - Class A airspace areas.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Class A airspace areas. 71.33 Section 71.33 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE... of the earth and the Alaska Peninsula west of longitude 160°00′00″ West. (c) The airspace areas...

High-Density Genetic Linkage Map Construction and Quantitative Trait Locus Mapping for Hawthorn (Crataegus pinnatifida Bunge).

PubMed

Zhao, Yuhui; Su, Kai; Wang, Gang; Zhang, Liping; Zhang, Jijun; Li, Junpeng; Guo, Yinshan

2017-07-14

Genetic linkage maps are an important tool in genetic and genomic research. In this study, two hawthorn cultivars, Qiujinxing and Damianqiu, and 107 progenies from a cross between them were used for constructing a high-density genetic linkage map using the 2b-restriction site-associated DNA (2b-RAD) sequencing method, as well as for mapping quantitative trait loci (QTL) for flavonoid content. In total, 206,411,693 single-end reads were obtained, with an average sequencing depth of 57× in the parents and 23× in the progeny. After quality trimming, 117,896 high-quality 2b-RAD tags were retained, of which 42,279 were polymorphic; of these, 12,951 markers were used for constructing the genetic linkage map. The map contained 17 linkage groups and 3,894 markers, with a total map length of 1,551.97 cM and an average marker interval of 0.40 cM. QTL mapping identified 21 QTLs associated with flavonoid content in 10 linkage groups, which explained 16.30-59.00% of the variance. This is the first high-density linkage map for hawthorn, which will serve as a basis for fine-scale QTL mapping and marker-assisted selection of important traits in hawthorn germplasm and will facilitate chromosome assignment for hawthorn whole-genome assemblies in the future.

Joint Airspace Control, Doctrine Update 10-06

DTIC Science & Technology

2010-05-20

Doctrine Update 10-06 Joint Publication 3-52, Joint Airspace Control JP 3-52 provides joint doctrine for airspace control across the full range...identification, combined operations, and unmanned aerial vehicle If you want read the complete new doctrine document, dated 20 May 2010, click here: JP 3-52...Joint Airspace Control. For more information, visit the LeMay Center for Doctrine Development and Education, call us at DSN 493-7442, or e-mail

77 FR 66069 - Amendment of Class E Airspace; Perry, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-01

...-1435; Airspace Docket No. 11-ACE-28] Amendment of Class E Airspace; Perry, IA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at Perry, IA... proposed rulemaking (NPRM) to amend Class E airspace for the Perry, IA, area, creating additional...

77 FR 66067 - Amendment of Class E Airspace; Boone, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-01

...-1432; Airspace Docket No. 11-ACE-25] Amendment of Class E Airspace; Boone, IA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at Boone, IA... proposed rulemaking (NPRM) to amend Class E airspace for the Boone, IA, area, creating additional...

77 FR 12992 - Amendment of Class E Airspace; Jacksonville, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-05

... the airport to aid in the navigation of our National Airspace System. The airport dimensions and... amending Class E surface airspace, and Class E airspace extending upward from 700 feet above the surface... change, and does not involve a change in the dimensions or operating requirements of that airspace...

76 FR 39259 - Establishment of Class E Airspace; Brunswick, ME

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-06

...-0116; Airspace Docket No. 11-ANE-1] Establishment of Class E Airspace; Brunswick, ME AGENCY: Federal... Class E airspace at Brunswick Executive Airport, Brunswick, ME. DATES: The effective date is moved from... Class E airspace at Brunswick Executive Airport, Brunswick, ME. This action will move up the effective...

75 FR 13667 - Amendment of Class E Airspace; Huntingburg, IN

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-23

...; Airspace Docket No. 09-AGL-21] Amendment of Class E Airspace; Huntingburg, IN AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at Huntingburg, IN... rulemaking to amend Class E airspace for Huntingburg Airport, Huntingburg, IN (74 FR 66592) Docket No. FAA...

75 FR 18403 - Amendment of Class E Airspace; Rifle, CO

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-12

...-1014; Airspace Docket No. 09-ANM-10] Amendment of Class E Airspace; Rifle, CO AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action will establish Class E airspace at Rifle, CO.... This action also changes the airport name in the existing Class E airspace description. DATES...

77 FR 46282 - Amendment of Class E Airspace; Sweetwater, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-03

...-0829; Airspace Docket No. 11-ASW-9] Amendment of Class E Airspace; Sweetwater, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at... Register a notice of proposed rulemaking (NPRM) to amend Class E airspace for the Sweetwater, TX, area...

77 FR 51464 - Amendment of Class E Airspace; Augusta, GA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-24

...-1334; Airspace Docket No. 11-ASO-43] Amendment of Class E Airspace; Augusta, GA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E Airspace in... amend Class E airspace in the Augusta, GA area (77 FR 21506). Interested parties were invited to...

75 FR 65224 - Amendment of Class E Airspace; Williston, ND

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-22

...-0407; Airspace Docket No. 10-AGL-7] Amendment of Class E Airspace; Williston, ND AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for... published in the Federal Register a notice of proposed rulemaking to amend Class E airspace for Williston...

78 FR 27031 - Amendment of Class E Airspace; Kingston, NY

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-09

...-0831; Airspace Docket No. 12-AEA-13] Amendment of Class E Airspace; Kingston, NY AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E Airspace at... published in the Federal Register a notice of proposed rulemaking to amend Class E airspace at Kingston, NY...

75 FR 41075 - Amendment of Class E Airspace; Bozeman, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-15

...-1220; Airspace Docket No. 09-ANM-30] Amendment of Class E Airspace; Bozeman, MT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action will amend Class E airspace at... proposed rulemaking to amend Class E airspace at Bozeman, MT (75 FR 20321). Interested parties were invited...

76 FR 55554 - Amendment of Class E Airspace; Rutherfordton, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

...-1330; Airspace Docket No. 10-ASO-41] Amendment of Class E Airspace; Rutherfordton, NC AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at... published in the Federal Register a notice of proposed rulemaking to amend Class E airspace 700 feet above...

76 FR 70865 - Modification of Class E Airspace; Driggs, ID

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-16

...-0837; Airspace Docket No. 11-ANM-17] Modification of Class E Airspace; Driggs, ID AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace at... were received. Class E airspace designations are published in paragraph 6005, of FAA Order 7400.9V...

77 FR 10649 - Modification of Class E Airspace; Douglas, AZ

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-23

...-1313; Airspace Docket No. 11-AWP-17] Modification of Class E Airspace; Douglas, AZ AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace at... airport, and corrects a typographical error in the legal description for the Class E 700 foot airspace...

77 FR 32896 - Modification of Class E Airspace; Billings, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-04

...-0316; Airspace Docket No. 12-ANM-1] Modification of Class E Airspace; Billings, MT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace at... were received. Class E airspace designations are published in paragraph 6005, of FAA Order 7400.9V...

75 FR 65226 - Establishment of Class E Airspace; Bamberg, SC

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-22

...-0685; Airspace Docket No. 10-ASO-27] Establishment of Class E Airspace; Bamberg, SC AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E Airspace... Register a notice of proposed rulemaking to establish Class E airspace at Bamberg, SC (75 FR 52654) Docket...

75 FR 65227 - Revocation of Class E Airspace; Franklin, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-22

...-0603; Airspace Docket No. 10-ASW-9] Revocation of Class E Airspace; Franklin, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action removes Class E airspace for... published in the Federal Register a notice of proposed rulemaking to remove Class E airspace for Franklin...

77 FR 38472 - Amendment of Class D Airspace; Pontiac, MI

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-28

...-1142; Airspace Docket No. 11-AGL-22] Amendment of Class D Airspace; Pontiac, MI AGENCY: Federal... Class D airspace within the Pontiac, MI, area by changing the name of the airport from [[Page 38473... County International Airport and adjusting the geographic coordinates within Class D airspace to coincide...

75 FR 43814 - Amendment of Class D Airspace; Goldsboro, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-27

...-0095; Airspace Docket No. 10-ASO-18] Amendment of Class D Airspace; Goldsboro, NC AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends the Class D Airspace at... published in the Federal Register a notice of proposed rulemaking to amend Class D airspace for Seymour...

78 FR 67296 - Establishment of Class D Airspace; Mesquite, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-12

...-0580; Airspace Docket No. 12-ASW-2] Establishment of Class D Airspace; Mesquite, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class D airspace... establish Class D airspace for Mesquite Metro Airport, Mesquite, TX (78 FR 48842) Docket No. FAA-2012- 0580...

76 FR 35369 - Proposed Establishment of Class D and Amendment of Class E Airspace; Los Angeles, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-17

... Angeles International Airport. The FAA is proposing this action to enhance the safety and management of... rulemaking (NPRM). SUMMARY: This action proposes to establish Class D airspace at Los Angeles International... be submitted in triplicate to the Docket Management System (see ADDRESSES section for address and...

Anti-inflammatory effect of the water fraction from hawthorn fruit on LPS-stimulated RAW 264.7 cells

PubMed Central

Li, Chunmei

2011-01-01

The hawthorn fruit (Crataegus pinnatifida Bunge var. typica Schneider) is used as a traditional medicine in Korea. The objective of this study was to understand the mechanisms of the anti-inflammatory effects of the water fractionated portion of hawthorn fruit on a lipopolysaccharide (LPS)-stimulated RAW 264.7 cellular model. The level of nitric oxide (NO) production in the water fraction and LPS-treated RAW 264.7 cells were determined with an ELISA. The cytotoxicity of the water fraction and LPS was measured with an MTT assay. Expression of nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), tumor necrosis factor (TNF)-α, interleukin 6 (IL-6), and interleukin 1β (IL-1β) mRNA were analyzed with a reverse transcription polymerase chain reaction (RT-PCR). The water fraction of hawthorn fruit was determined to be safe and significantly inhibited NO production in LPS-stimulated RAW 264.7 cells and suppressed COX-2, TNF-α, IL-1β, and IL-6 expression. The observed anti-inflammatory effects of the water fraction of hawthorn fruit might be attributed to the down-regulation of COX-2, TNF-α, IL-1β, and IL-6 expression in LPS-stimulated RAW 264.7 cells. PMID:21556222

77 FR 5 - Amendment of Class E Airspace; Kipnuk, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-03

...-0866; Airspace Docket No. 11-AAL-15] Amendment of Class E Airspace; Kipnuk, AK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace at Kipnuk, AK. The... a notice of proposed rulemaking (NPRM) to amend controlled airspace at Kipnuk, AK (76 FR 54149...

78 FR 57788 - Amendment of Class E Airspace; Everett, WA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-20

...-0434; Airspace Docket No. 13-ANM-1] Amendment of Class E Airspace; Everett, WA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace at Everett, WA, to... the FAA. No comments were received. Class E airspace designations are published in paragraph 6004, of...

77 FR 68067 - Establishment of Class E Airspace; Coaldale, NV

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-15

...-0705; Airspace Docket No. 12-AWP-4] Establishment of Class E Airspace; Coaldale, NV AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E airspace... forth in the NPRM for lowering the Class E airspace down to 1,200 feet above the surface was vague and...

76 FR 2800 - Establishment of Class E Airspace; Lucin, UT

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-18

...-2010-1208; Airspace Docket No. 10-ANM-16] Establishment of Class E Airspace; Lucin, UT AGENCY: Federal... E en route domestic airspace for the Lucin VORTAC, Lucin, UT. DATES: Effective 0901 UTC, February 17..., UT, incorrectly referenced the existing Class E en route domestic airspace exclusion above 8,500 feet...

78 FR 33963 - Amendment of Class E Airspace; Atwood, KS

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-06

...; Airspace Docket No. 11-ACE-24] Amendment of Class E Airspace; Atwood, KS AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at Atwood, KS... published in the Federal Register a notice of proposed rulemaking (NPRM) to amend Class E airspace for the...

77 FR 68681 - Amendment of Class E Airspace; Anthony, KS

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-16

...-0652; Airspace Docket No. 12-ACE-4] Amendment of Class E Airspace; Anthony, KS AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at Anthony, KS... the Federal Register a notice of proposed rulemaking (NPRM) to amend Class E airspace for the Anthony...

77 FR 5169 - Amendment of Class D Airspace; Saginaw, MI

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-02

...-1144; Airspace Docket No. 11-AGL-24] Amendment of Class D Airspace; Saginaw, MI AGENCY: Federal... Class D airspace within the Saginaw, MI, area by changing the name of the airport from Tri-City... International Airport and updating the geographic coordinates within Class D airspace to coincide with the FAA's...

77 FR 5170 - Amendment of Class D Airspace; Jackson, MI

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-02

...-1143; Airspace Docket No. 11-AGL-23] Amendment of Class D Airspace; Jackson, MI AGENCY: Federal... Class D airspace within the Jackson, MI, area by changing the name of the airport from Jackson County... Class D airspace to coincide with the FAA's aeronautical database. This is an administrative change and...

76 FR 55555 - Amendment of Class E Airspace; Shelby, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-08

...-0280; Airspace Docket No. 11-ASO-16] Amendment of Class E Airspace; Shelby, NC AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E Airspace at Shelby, NC, to... rulemaking to amend Class E airspace at Shelby, NC (76 FR 35799) Docket No. FAA-2011-0280. Interested parties...

76 FR 28887 - Revocation of Class E Airspace; Ozark, MO

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-19

...-0432; Airspace Docket No. 11-ACE-8] Revocation of Class E Airspace; Ozark, MO AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action removes Class E airspace at Ozark, MO... Regulations (14 CFR) Part 71 by removing Class E airspace in the Ozark, MO, area. Abandonment of the former...

75 FR 13669 - Amendment of Class E Airspace; Dumas, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-23

...-1151; Airspace Docket No. 09-ASW-30] Amendment of Class E Airspace; Dumas, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for Dumas, TX, adding... published in the Federal Register a notice of proposed rulemaking to amend Class E airspace for Dumas, TX...

76 FR 35966 - Amendment of Class E Airspace; Cocoa, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-21

...-0070; Airspace Docket No. 10-ASO-43] Amendment of Class E Airspace; Cocoa, FL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E Airspace at Cocoa, FL, as the... published in the Federal Register a notice of proposed rulemaking to amend Class E airspace at Merritt...

76 FR 53049 - Amendment of Class E Airspace; Shelby, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-25

...-0536; Airspace Docket No. 11-ANM-13] Amendment of Class E Airspace; Shelby, MT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action modifies Class E airspace at Shelby, MT, to... E airspace designations are published in paragraph 6005 of FAA Order 7400.9U dated August 18, 2010...

75 FR 17891 - Amendment of Class D Airspace; Goldsboro, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-08

...-0095; Airspace Docket No. 10-ASO-18] Amendment of Class D Airspace; Goldsboro, NC AGENCY: Federal... proposes to amend the Class D airspace at Seymour Johnson AFB, Goldsboro, NC, to reflect the part-time... amend Class D airspace at Seymour Johnson AFB, Goldsboro, NC, to reflect the part-time operations of the...

78 FR 48291 - Amendment of Class D Airspace; Sparta, WI

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-08

...-0165; Airspace Docket No. 13-AGL-6] Amendment of Class D Airspace; Sparta, WI AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class D airspace at Sparta, WI... Register a notice of proposed rulemaking (NPRM) to amend Class D airspace for Sparta/Fort McCoy Airport (78...

75 FR 39145 - Amendment of Class C Airspace; Flint, MI

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-08

...-0599; Airspace Docket No. 10-AWA-3] RIN 2120-AA66 Amendment of Class C Airspace; Flint, MI AGENCY... description of the Bishop International Airport, Flint, MI, Class C airspace area by amending the airport... defines the Class C airspace area's center point. The Rule This action amends Title 14 Code of Federal...

78 FR 26243 - Amendment of Class E Airspace; Easton, PA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-06

...-0394; Airspace Docket No. 12-AEA-8] Amendment of Class E Airspace; Easton, PA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E Airspace at Easton, PA, as the... (NPRM) to amend Class E airspace at Easton, PA (78 FR 5152) Docket No. FAA-2012-0394. Interested parties...

76 FR 9965 - Amendment of Class E Airspace and Revocation of Class E Airspace; Easton, MD

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-23

...-5588. SUPPLEMENTARY INFORMATION: History On October 22, 2010, the FAA published in the Federal Register...] * * * * * Paragraph 6005 Class E Airspace Areas Extending Upward from 700 feet or More Above the Surface of the Earth...]04'08'' W.) That airspace extending upward from 700 feet above the surface of the Earth within a 6.5...

14 CFR 61.95 - Operations in Class B airspace and at airports located within Class B airspace.

Code of Federal Regulations, 2010 CFR

2010-01-01

... unless: (1) The student pilot has received both ground and flight training from an authorized instructor on that Class B airspace area, and the flight training was received in the specific Class B airspace... the authorized instructor who gave the student pilot flight training, and the endorsement is dated...

14 CFR 61.95 - Operations in Class B airspace and at airports located within Class B airspace.

Code of Federal Regulations, 2011 CFR

2011-01-01

... unless: (1) The student pilot has received both ground and flight training from an authorized instructor on that Class B airspace area, and the flight training was received in the specific Class B airspace... the authorized instructor who gave the student pilot flight training, and the endorsement is dated...

78 FR 65208 - Modification of Class D and E Airspace; Kenai, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-31

...-1174; Airspace Docket No. 12-AAL-12] Modification of Class D and E Airspace; Kenai, AK AGENCY: Federal... airspace at Kenai Municipal Airport, Kenai, AK. Controlled airspace is necessary to accommodate aircraft... (NPRM) to modify controlled airspace at Kenai Municipal Airport, Kenai, AK (78 FR 34609). Interested...

Activity of hawthorn leaf and bark extracts in relation to biological membrane.

PubMed

Włoch, Aleksandra; Kapusta, Ireneusz; Bielecki, Krzysztof; Oszmiański, Jan; Kleszczyńska, Halina

2013-07-01

The aim of the study was to identify and determine the percent content of polyphenols in extracts from leaves and hawthorn bark, to examine the effect of the extracts on the properties of the biological membrane as well as to determine their antioxidant activity toward membrane lipids. In particular, a biophysical investigation was conducted on the effect of hawthorn extracts on the osmotic resistance and morphology of erythrocyte cells and on the packing of the heads of membrane lipids. Analysis of the polyphenol content of extracts used the HPLC method. Analysis of the polyphenol composition has shown a dominant share of procyanidins and epicatechin in both extracts. The research showed that the polyphenolic compounds contained in hawthorn extracts are incorporated mainly into the hydrophilic part of the erythrocyte membrane, inducing echinocyte shapes. They also diminish the packing order of the lipid polar heads of the membrane, as evidenced by the lowered generalized polarization values of Laurdan. The substances used induced increased osmotic pressure of erythrocytes, making them less sensitive to changes in osmotic pressure. The presence of the extract compounds in the outer hydrophilic part of the erythrocyte membrane, evidenced by examination of the shapes and packing in the hydrophilic part of membrane, indicates that the substances constitute a kind of barrier that protects the erythrocyte membrane against free radicals, while the membrane-bound extracts do not disturb the membrane structure and, thus, do not cause any side effects.

78 FR 47237 - Proposed Amendment of Class E Airspace; Chariton, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-05

...-0255; Airspace Docket No. 13-ACE-4] Proposed Amendment of Class E Airspace; Chariton, IA AGENCY... action proposes to amend Class E airspace at Chariton, IA. Decommissioning of the Chariton non... for standard instrument approach procedures at Chariton Municipal Airport, Chariton, IA. Airspace...

Phenylpropanoid-substituted procyanidins and tentatively identified procyanidin glycosides from hawthorn (Crataegus spp.).

PubMed

Sendker, Jandirk; Petereit, Frank; Lautenschläger, Marcus; Hellenbrand, Nils; Hensel, Andreas

2013-01-01

The rational use of hawthorn leafs and flowers from Crataegus spp. for declining cardiac performance is mainly due to flavon-C-glycosides and oligomeric procyanidins (OPC). From OPC-enriched extracts from different batches, a dimeric phenylpropanoid-substituted procyanidin (cinchonain II b, 1) was isolated and characterized by MS, CD, and NMR. Also the presence of higher oligomeric cinchonains (degree of polymerization 3 to 8) in hawthorn extracts was shown by a specific ultrahigh-pressure liquid chromatography-ESI-qTOF-MS method. Interestingly, strong evidence for the occurrence of oligomeric procyanidin hexosides was found by ultrahigh-pressure liquid chromatography-ESI-qTOF-MS analysis which additionally revealed the presence of peaks indicative of dimeric procyanidin hexosides by their exact mass, which were clearly distinguishable from the cinchonain II type peaks. Georg Thieme Verlag KG Stuttgart · New York.

78 FR 48299 - Establishment of Class D Airspace; Bryant AAF, Anchorage, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-08

...-0433; Airspace Docket No. 12-AAL-5] Establishment of Class D Airspace; Bryant AAF, Anchorage, AK AGENCY... airspace at Bryant Army Airfield (AAF), Anchorage AK. This action provides controlled airspace to improve... proposed rulemaking (NPRM) to establish Class D airspace at Bryant AAF, Anchorage AK (77 FR 50646...

77 FR 71362 - Proposed Amendment of Class E Airspace; Decorah, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-30

...-1433; Airspace Docket No. 11-ACE-26] Proposed Amendment of Class E Airspace; Decorah, IA AGENCY... action proposes to amend Class E airspace at Decorah, IA. Decommissioning of the Decorah non-directional... instrument approach procedures at Decorah Municipal Airport, Decorah, IA. Airspace reconfiguration is...

76 FR 14824 - Proposed Establishment of Class E Airspace; Brunswick, ME

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-18

...-0116; Airspace Docket No. 11-ANE-1] Proposed Establishment of Class E Airspace; Brunswick, ME AGENCY... action proposes to establish Class E Airspace at Brunswick, ME, to accommodate new Standard Instrument... Brunswick, ME to provide airspace required to support the standard instrument approach procedures developed...

76 FR 78180 - Proposed Modification of Class E Airspace; Douglas, AZ

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-16

...-1313; Airspace Docket No. 11-AWP-17] Proposed Modification of Class E Airspace; Douglas, AZ AGENCY... action proposes to modify Class E airspace at Bisbee Douglas International Airport, Douglas, AZ... feet above the surface at Douglas, AZ. Additional controlled airspace is necessary to accommodate...

76 FR 21828 - Proposed Amendment of Class E Airspace; Mobridge, SD

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-19

...-0134; Airspace Docket No. 11-AGL-3] Proposed Amendment of Class E Airspace; Mobridge, SD AGENCY... action proposes to amend Class E airspace at Mobridge, SD. Additional controlled airspace is necessary to... accommodate new standard instrument approach procedures at Mobridge Municipal Airport, Mobridge, SD...

77 FR 37569 - Establishment of Class D Airspace and Amendment of Class E Airspace; East Hampton, NY

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-22

... accommodate the new mobile airport traffic control tower (ATCT) at East Hampton Airport. Controlled airspace... helicopter operators to enter into a Letter of Agreement (LOA) with the FAA. Use of these rules will allow the helicopter operators to minimize any delays they may experience due to the airspace, as well as...

Survey of flue gas desulfurization systems: Hawthorn Station, Kansas City Power and Light Co. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Isaacs, G.A.; Zada, F.K.

1975-09-01

Results are given of a survey of the flue gas desulfurization (FGD) systems at Kansas City Power and Light Co.'s Hawthorn Power Station. The FGD systems on Hawthorn boilers 3 and 4 were designed to operate by injection of dry limestone in the boiler's furnace, followed by tail gas scrubbing. Because of tube plugging in boiler 4 the mode of operation of the FGD system on that boiler was modified: ground limestone is now introduced into the flue gas near the gas inlet to the scrubber tower. (GRA)

75 FR 13453 - Proposed Amendment of Class E Airspace; Corpus Christi, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-22

...-0089; Airspace Docket No. 10-ASW-1] Proposed Amendment of Class E Airspace; Corpus Christi, TX AGENCY... action proposes to amend Class E airspace in the Corpus Christi, TX area. Additional controlled airspace... adding additional Class E airspace extending upward from 700 feet above the surface in the Corpus Christi...

76 FR 5302 - Proposed Amendment of Class E Airspace; Terre Haute, IN

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-31

...-1034; Airspace Docket No. 10-AGL-22] Proposed Amendment of Class E Airspace; Terre Haute, IN AGENCY... action proposes to amend Class E airspace at Terre Haute, IN. Controlled airspace is necessary to... (POINT-IN-SPACE) SIAP at Union Hospital Heliport, Terre Haute, IN. Controlled airspace is needed for the...

76 FR 53360 - Proposed Establishment of Class E Airspace; Stuart, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-26

...-0831; Airspace Docket No. 11-ACE-17] Proposed Establishment of Class E Airspace; Stuart, IA AGENCY... action proposes to establish Class E airspace at Stuart, IA. Controlled airspace is necessary to... surface for new standard instrument approach procedures at the City of Stuart Helistop, Stuart, IA...

76 FR 31510 - Proposed Amendment of Class E Airspace; Rutherfordton, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-01

...; Airspace Docket No. 10-ASO-41) and be submitted in triplicate to the Docket Management System (see... airspace required to support new standard instrument approach procedures for Rutherford County Airport. The... action proposes to amend Class E Airspace at Rutherfordton, NC, to accommodate the additional airspace...

77 FR 16783 - Proposed Amendment of Class E Airspace; Orlando, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-22

...-0503; Airspace Docket No. 11-ASO-19] Proposed Amendment of Class E Airspace; Orlando, FL AGENCY... action proposes to amend Class E Airspace at Orlando, FL, as new Standard Instrument Approach Procedures have been developed at Orlando Executive Airport. This action would enhance the safety and airspace...

78 FR 73751 - Proposed Amendment of Class E Airspace; Philip, SD

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-09

...-0916; Airspace Docket No. 13-AGL-30] Proposed Amendment of Class E Airspace; Philip, SD AGENCY: Federal... proposes to amend Class E airspace at Philip, SD. Additional controlled airspace is necessary to... the surface to accommodate new standard instrument approach procedures at Philip Airport, Philip, SD...

78 FR 65237 - Proposed Establishment of Class E Airspace; Central, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-31

...-0017; Airspace Docket No. 13-AAL-1] Proposed Establishment of Class E Airspace; Central, AK AGENCY... action proposes to establish Class E airspace at Central Airport, Central, AK. Controlled airspace is... of aircraft operations at Central Airport, Central, AK. DATES: Comments must be received on or before...

77 FR 9840 - Amendment of Class E Airspace; Colorado Springs, CO

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-21

...-1191; Airspace Docket No. 11-ANM-21] Amendment of Class E Airspace; Colorado Springs, CO AGENCY... airspace at City of Colorado Springs Municipal Airport, Colorado Springs, CO. Decommissioning of the Black... controlled airspace at Colorado Springs, CO (76 FR 70920). Interested parties were invited to participate in...

76 FR 44288 - Establishment of Class E Airspace; New Market, VA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-25

...-380; Airspace Docket No. 11-AEA-12] Establishment of Class E Airspace; New Market, VA AGENCY: Federal... proposes to establish Class E Airspace at New Market, VA, to accommodate the additional airspace needed for the Standard Instrument Approach Procedures developed for New Market Airport. This action would...

76 FR 30299 - Proposed Establishment of Class E Airspace; Kayenta, AZ

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-25

...-0393; Airspace Docket No. 11-AWP-2] Proposed Establishment of Class E Airspace; Kayenta, AZ AGENCY... action proposes to establish Class E Airspace at Kayenta Airport, Kayenta, AZ. Controlled airspace is...) standard instrument approach procedures at Kayenta Airport. The FAA is proposing this action to enhance the...

77 FR 5169 - Amendment of Class E Airspace; South Bend, IN

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-02

...-0250; Airspace Docket No. 11-AGL-6] Amendment of Class E Airspace; South Bend, IN AGENCY: Federal... South Bend, IN, area. Additional controlled airspace is necessary to accommodate new Area Navigation... South Bend, IN, area, creating additional controlled airspace at Jerry Tyler Memorial Airport (76 FR...

75 FR 17851 - Amendment of Class E Airspace; Dallas-Fort Worth, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-08

...-0926; Airspace Docket No. 09-ASW-26] Amendment of Class E Airspace; Dallas-Fort Worth, TX AGENCY... airspace in the Dallas-Fort Worth, TX area. Additional controlled airspace is necessary to accommodate new... proposed rulemaking to amend Class E airspace for the Dallas- Fort Worth, TX area (74 FR 57617) Docket No...

78 FR 52422 - Amendment of Class D and E Airspace; Wrightstown, NJ

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-23

...-0565; Airspace Docket No. 13-AEA-11] Amendment of Class D and E Airspace; Wrightstown, NJ AGENCY... amends Class D and E Airspace at Wrightstown, NJ, by updating the geographic coordinates and changing the... (14 CFR) part 71 amends Class D airspace and E airspace designated as an extension to a Class D...

Transcriptome Analysis and Ultrastructure Observation Reveal that Hawthorn Fruit Softening Is due to Cellulose/Hemicellulose Degradation

PubMed Central

Xu, Jiayu; Zhao, Yuhui; Zhang, Xiao; Zhang, Lijie; Hou, Yali; Dong, Wenxuan

2016-01-01

Softening, a common phenomenon in many fruits, is a well coordinated and genetically determined process. However, the process of flesh softening during ripening has rarely been described in hawthorn. In this study, we found that ‘Ruanrou Shanlihong 3 Hao’ fruits became softer during ripening, whereas ‘Qiu JinXing’ fruits remained hard. At late developmental stages, the firmness of ‘Ruanrou Shanlihong 3 Hao’ fruits rapidly declined, and that of ‘Qiu JinXing’ fruits remained essentially unchanged. According to transmission electron microscopy, the middle lamella of ‘Qiu JinXing’ and ‘Ruanrou Shanlihong 3 Hao’ fruit flesh was largely degraded as the fruits matured. Microfilaments in ‘Qiu JinXing’ flesh were arranged close together and were deep in color, whereas those in ‘Ruanrou Shanlihong 3 Hao’ fruit flesh were arranged loosely, partially degraded and light in color. RNA-Seq analysis yielded approximately 46.72 Gb of clean data and 72,837 unigenes. Galactose metabolism and pentose and glucuronate interconversions are involved in cell wall metabolism, play an important role in hawthorn texture. We identified 85 unigenes related to the cell wall between hard- and soft-fleshed hawthorn fruits. Based on data analysis and real-time PCR, we suggest that β-GAL and PE4 have important functions in early fruit softening. The genes Ffase, Gns,α-GAL, PE63, XTH, and CWP, which are involved in cell wall degradation, are responsible for the different textures of hawthorn fruits. Thus, we hypothesize that the different textures of ‘Qiu JinXing’ and ‘Ruanrou Shanlihong 3 Hao’ fruits at maturity mainly result from cellulose/hemicelluloses degradation rather than from lamella degradation. Overall, we propose that different types of hydrolytic enzymes in cells interact to degrade the cell wall, resulting in ultramicroscopic Structure changes in the cell wall and, consequently, fruit softening. These results provide fundamental insight

76 FR 3571 - Proposed Establishment of Class E Airspace; Kahului, HI

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-20

...-1233; Airspace Docket No. 10-AWP-21] Proposed Establishment of Class E Airspace; Kahului, HI AGENCY... action proposes to establish Class E airspace at Kahului Airport, Kahului, HI. Controlled airspace is... procedures at Kahului Airport, Kahului, HI. The FAA is proposing this action to enhance the safety and...

75 FR 6592 - Proposed Amendment of Class E Airspace; Emmetsburg, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

...-1153; Airspace Docket No. 09-ACE-13] Proposed Amendment of Class E Airspace; Emmetsburg, IA AGENCY... action proposes to amend Class E airspace at Emmetsburg, IA. Additional controlled airspace is necessary..., Emmetsburg, IA. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules...

77 FR 68683 - Amendment of Class E Airspace; Forest City, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-16

...-0654; Airspace Docket No. 12-ACE-3] Amendment of Class E Airspace; Forest City, IA AGENCY: Federal... Forest City, IA. Additional controlled airspace is necessary to accommodate new Area Navigation (RNAV... Federal Register a notice of proposed rulemaking (NPRM) to amend Class E airspace for the Forest City, IA...

77 FR 45985 - Proposed Amendment of Class E Airspace; Lincoln, ME

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-02

...-0764; Airspace Docket No. 12-ANE-12] Proposed Amendment of Class E Airspace; Lincoln, ME AGENCY... action proposes to amend Class E Airspace at Lincoln, ME, as the Lincoln Non-Directional Radio Beacon..., Lincoln, ME. Airspace reconfiguration is necessary due to the decommissioning of the Lincoln NDB and...

78 FR 65238 - Proposed Establishment of Class E Airspace; Eagle, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-31

...-0777; Airspace Docket No. 12-AAL-16] Proposed Establishment of Class E Airspace; Eagle, AK AGENCY... action proposes to establish Class E airspace at Eagle Airport, Eagle, AK. Controlled airspace is... management of aircraft operations at Eagle Airport, Eagle, AK. DATES: Comments must be received on or before...

78 FR 69787 - Proposed Modification of Class E Airspace; Sitka, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-21

...-0921; Airspace Docket No. 13-AAL-4] Proposed Modification of Class E Airspace; Sitka, AK AGENCY... rulemaking (NPRM). SUMMARY: This action proposes to modify Class E airspace at Sitka, AK, to [[Page 69788... Gutierrez, AK. After review of the airspace, the FAAs Western Terminal Products Office found modification of...

78 FR 74006 - Amendment of Class E Airspace; Green Bay, WI

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-10

...-0941; Airspace Docket No. 13-AGL-32] Amendment of Class E Airspace; Green Bay, WI AGENCY: Federal... Class E airspace within the Green Bay, WI, area by updating the geographic coordinates for Austin... coordinates, within Class E airspace, of Austin-Straubel International Airport, Green Bay, WI, to coincide...

75 FR 15360 - Proposed Amendment of Class E Airspace; Austin, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-29

...-1152; Airspace Docket No. 09-ASW-31] Proposed Amendment of Class E Airspace; Austin, TX AGENCY: Federal... proposes to amend Class E airspace in the Austin, TX area. Additional controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAPs) at Austin Executive Airport, Austin, TX. The...

UTM Safely Enabling UAS Operations in Low-Altitude Airspace

NASA Technical Reports Server (NTRS)

Kopardekar, Parimal

2017-01-01

Conduct research, development and testing to identify airspace operations requirements to enable large-scale visual and beyond visual line of sight UAS operations in the low-altitude airspace. Use build-a-little-test-a-little strategy remote areas to urban areas Low density: No traffic management required but understanding of airspace constraints. Cooperative traffic management: Understanding of airspace constraints and other operations. Manned and unmanned traffic management: Scalable and heterogeneous operations. UTM construct consistent with FAAs risk-based strategy. UTM research platform is used for simulations and tests. UTM offers path towards scalability.

UTM Safely Enabling UAS Operations in Low-Altitude Airspace

NASA Technical Reports Server (NTRS)

Kopardekar, Parimal H.

2016-01-01

Conduct research, development and testing to identify airspace operations requirements to enable large-scale visual and beyond visual line of sight UAS operations in the low-altitude airspace. Use build-a-little-test-a-little strategy remote areas to urban areas Low density: No traffic management required but understanding of airspace constraints. Cooperative traffic management: Understanding of airspace constraints and other operations. Manned and unmanned traffic management: Scalable and heterogeneous operations. UTM construct consistent with FAAs risk-based strategy. UTM research platform is used for simulations and tests. UTM offers path towards scalability.

76 FR 38580 - Proposed Amendment of Class D Airspace; Eglin AFB, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-01

...-0087; Airspace Docket No. 11-ASO-12] Proposed Amendment of Class D Airspace; Eglin AFB, FL AGENCY... action proposes to amend Class D Airspace in the Eglin Air Force Base (AFB), FL airspace area. The Destin... amendment to Title 14, Code of Federal Regulations (14 CFR) part 71 to amend Class D airspace in the Eglin...

75 FR 6595 - Proposed Amendment of Class E Airspace; Mapleton, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

...-1155; Airspace Docket No. 09-ACE-14] Proposed Amendment of Class E Airspace; Mapleton, IA AGENCY... action proposes to amend Class E airspace at Mapleton, IA. Additional controlled airspace is necessary to..., Mapleton, IA. The FAA is taking this action to enhance the safety and management of Instrument Flight Rules...

76 FR 3570 - Proposed Amendment of Class E Airspace; Taylor, AZ

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-20

...-1189; Airspace Docket No. 10-AWP-19] Proposed Amendment of Class E Airspace; Taylor, AZ AGENCY: Federal... proposes to modify Class E airspace at Taylor Airport, Taylor, AZ. Controlled airspace is necessary to accommodate aircraft using the CAMBO One Departure Area Navigation (RNAV) out of Taylor Airport. The FAA is...

78 FR 17083 - Amendment of Class E Airspace; Scammon Bay, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-20

...-0121; Airspace Docket No. 12-AAL-2] Amendment of Class E Airspace; Scammon Bay, AK AGENCY: Federal... Scammon Bay Airport, Scammon Bay, AK. Controlled airspace is necessary to accommodate aircraft using a new... Federal Register a notice of proposed rulemaking to modify controlled airspace at Scammon Bay, AK (77 FR...

76 FR 39038 - Proposed Establishment of Class E Airspace; Lebanon, PA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-05

...-0558; Airspace Docket No. 11-AEA-13] Proposed Establishment of Class E Airspace; Lebanon, PA AGENCY... action proposes to establish Class E Airspace at Lebanon, PA, to accommodate new Standard Instrument... amendment to Title 14, Code of Federal Regulations (14 CFR) part 71 to establish Class E airspace at Lebanon...

77 FR 40488 - Amendment of Class D and Class E Airspace; Lakehurst, NJ

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-10

...-0456; Airspace Docket No. 12-AEA-9] Amendment of Class D and Class E Airspace; Lakehurst, NJ AGENCY... changes the name of the airport associated with the Class D and Class E airspace at Lakehurst, NJ. The... associated with the Class D airspace and Class E airspace designated as an extension to a Class D airspace...

Interaction of Airspace Partitions and Traffic Flow Management Delay

NASA Technical Reports Server (NTRS)

Palopo, Kee; Chatterji, Gano B.; Lee, Hak-Tae

2010-01-01

To ensure that air traffic demand does not exceed airport and airspace capacities, traffic management restrictions, such as delaying aircraft on the ground, assigning them different routes and metering them in the airspace, are implemented. To reduce the delays resulting from these restrictions, revising the partitioning of airspace has been proposed to distribute capacity to yield a more efficient airspace configuration. The capacity of an airspace partition, commonly referred to as a sector, is limited by the number of flights that an air traffic controller can safely manage within the sector. Where viable, re-partitioning of the airspace distributes the flights over more efficient sectors and reduces individual sector demand. This increases the overall airspace efficiency, but requires additional resources in some sectors in terms of controllers and equipment, which is undesirable. This study examines the tradeoff of the number of sectors designed for a specified amount of traffic in a clear-weather day and the delays needed for accommodating the traffic demand. Results show that most of the delays are caused by airport arrival and departure capacity constraints. Some delays caused by airspace capacity constraints can be eliminated by re-partitioning the airspace. Analyses show that about 360 high-altitude sectors, which are approximately today s operational number of sectors of 373, are adequate for delays to be driven solely by airport capacity constraints for the current daily air traffic demand. For a marginal increase of 15 seconds of average delay, the number of sectors can be reduced to 283. In addition, simulations of traffic growths of 15% and 20% with forecasted airport capacities in the years 2018 and 2025 show that delays will continue to be governed by airport capacities. In clear-weather days, for small increases in traffic demand, increasing sector capacities will have almost no effect on delays.

77 FR 28243 - Amendment of Class D Airspace; Cocoa Beach, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-14

...-0099; Airspace Docket No. 12-ASO-11] Amendment of Class D Airspace; Cocoa Beach, FL AGENCY: Federal... Federal Register on April 11, 2012 that amends Class D airspace at Cocoa Beach, FL. DATES: Effective 0901...), amends Class D airspace at Cape Canaveral Skid Strip, Cocoa Beach, FL. A typographical error was made in...

78 FR 25229 - Proposed Establishment of Class E Airspace; Stockton, KS

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-30

...-0274; Airspace Docket No. 13-ACE-2] Proposed Establishment of Class E Airspace; Stockton, KS AGENCY... the docket number FAA-2013-0274/Airspace Docket No. 13- ACE-2, at the beginning of your comments. You... No. FAA-2013-0274/ Airspace Docket No. 13-ACE-2.'' The postcard will be date/time stamped and...

75 FR 81518 - Proposed Establishment of Class E Airspace; Wolfeboro, NH

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-28

...-1007; Airspace Docket No. 10-ANE-109] Proposed Establishment of Class E Airspace; Wolfeboro, NH AGENCY...-1007; Airspace Docket No. 10-ANE-109, at the beginning of your comments. You may also submit and review... is made: ``Comments to Docket No. FAA-2010-1007; Airspace Docket No. 10-ANE-109.'' The postcard will...

77 FR 4712 - Proposed Establishment of Class E Airspace; Pender, NE

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-31

...-1103; Airspace Docket No. 11-ACE-14] Proposed Establishment of Class E Airspace; Pender, NE AGENCY... the docket number FAA-2011-1103/Airspace Docket No. 11- ACE-14, at the beginning of your comments. You... made: ``Comments to Docket No. FAA-2011-1103/ Airspace Docket No. 11-ACE-14.'' The postcard will be...

Flexible Airspace Management (FAM) Research 2010 Human-in-the-Loop Simulation

NASA Technical Reports Server (NTRS)

Lee, Paul U.; Brasil, Connie; Homola, Jeffrey; Kessell, Angela; Prevot, Thomas; Smith, Nancy

2011-01-01

A human-in-the-Ioop (HITL) simulation was conducted to assess potential user and system benefits of Flexible Airspace Management (FAM) concept, as well as designing role definitions, procedures, and tools to support the FAM operations in the mid-term High Altitude Airspace (HAA) environment. The study evaluated the benefits and feasibility of flexible airspace reconfiguration in response to traffic overload caused by weather deviations, and compared them to those in a baseline condition without the airspace reconfiguration. The test airspace consisted of either four sectors in one Area of Specialization or seven sectors across two Areas. The test airspace was assumed to be at or above FL340 and fully equipped Vvith data communications (Data Comm). Other assumptions were consistent with those of the HAA concept. Overall, results showed that FAM operations with multiple Traffic Management Coordinators, Area Supervisors, and controllers worked remarkably well. The results showed both user and system benefits, some of which include the increased throughput, decreased flight distance, more manageable sector loads, and better utilized airspace. Also, the roles, procedures, airspace designs, and tools were all very well received. Airspace configuration options that resulted from a combination of algorithm-generated airspace configurations with manual modifications were well acceptec and posed little difficuIty and/or workload during airspace reconfiguration process. The results suggest a positive impact of FAM operations in HAA. Further investigation would be needed to evaluate if the benefits and feasibility would extend in either non-HAA or mixed equipage environment.

Gall production on hawthorns caused by Gymnosporangium spp.in Hatay province, Turkey

USDA-ARS?s Scientific Manuscript database

Three hawthorn and related rust diseases caused by Gymnosporangium confusum on Crataegus monogyna, G. clavariiforme on C. orientalis, and G. sabinae on Pyrus communis were detected in Hatay province, Turkey. Gymnosporangium confusum was also found causing telial galls on Juniperus communis. Gymnospo...

77 FR 17362 - Proposed Modification of Class D and Class E Airspace and Revocation of Class E Airspace...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-26

... (IFR) at Bellingham International Airport. This action also would remove Class E airspace designated as an extension to a Class D or E surface area at Bellingham International Airport. This action, initiated by the biennial review of the Bellingham airspace area, would enhance the safety and management of...

78 FR 6261 - Proposed Amendment of Class E Airspace; Griffin, GA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-30

... Airport, Griffin, GA (Lat. 33[deg]13'37'' N., long. 84[deg]16'30'' W.) That airspace extending upward from...-1219; Airspace Docket No. 12-ASO-43] Proposed Amendment of Class E Airspace; Griffin, GA AGENCY... action proposes to amend Class E Airspace at Griffin, GA, as the Griffin Non-Directional Beacon (NDB) has...

78 FR 52114 - Proposed Amendment of Class E Airspace; Macon, GA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-22

..., GA (Lat. 32[deg]41'34'' N., long. 83[deg]38'57'' W.) Macon Downtown Airport (Lat. 32[deg]49'18'' N...-0552; Airspace Docket No. 13-ASO-14] Proposed Amendment of Class E Airspace; Macon, GA AGENCY: Federal... proposes to amend Class E Airspace at Macon, GA, as the Bay Creek NDB has been decommissioned and airspace...

75 FR 23581 - Amendment of Class E Airspace; Emmetsburg, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-04

...-1153; Airspace Docket No. 09-ACE-13] Amendment of Class E Airspace; Emmetsburg, IA AGENCY: Federal... Emmetsburg, IA, adding additional controlled airspace to accommodate Area Navigation (RNAV) Standard Instrument Approach Procedures (SIAPs) at Emmetsburg Municipal Airport, Emmetsburg, IA. The FAA is taking...

75 FR 4270 - Establishment of Class E Airspace; Tompkinsville, KY

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-27

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-0604; Airspace Docket No. 09-ASO-18] Establishment of Class E Airspace; Tompkinsville, KY AGENCY... September 14, 2009 that establishes Class E Airspace at Tompkinsville--Monroe County Airport, Tompkinsville...

Energy Engineering Analysis Program, limited energy study of steam distribution systems, Hawthorne Army Ammunition Depot, Hawthorne, Nevada. Energy report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-07-01

This report summarizes all work of the Limited Energy Study of Steam Distribution Systems, Energy Engineering Analysis Program, Hawthorne Army Ammunition Depot (HWAAD), Nevada. The purpose of this limited energy study is to evaluate steam distribution and condensate collection systems in both the Industrial Area and Ordnance Area of HWAAD to develop a set of replacement actions that will reduce energy consumption and operating costs. These efforts consist of corrections and revisions to previously submitted funding requests. A number of facilities covering over 140,000 acres constitute HWAAD; however, this study was limited to the Industrial and Ordnance Areas.

32 CFR 989.28 - Airspace and range proposals.

Code of Federal Regulations, 2011 CFR

2011-07-01

... initiated by the FAA affect military use, the roles are reversed. The proponent's action officers (civil engineering and local airspace management) must ensure that the FAA is fully integrated into the airspace...

32 CFR 989.28 - Airspace and range proposals.

Code of Federal Regulations, 2013 CFR

2013-07-01

... initiated by the FAA affect military use, the roles are reversed. The proponent's action officers (civil engineering and local airspace management) must ensure that the FAA is fully integrated into the airspace...

32 CFR 989.28 - Airspace and range proposals.

Code of Federal Regulations, 2014 CFR

2014-07-01

... initiated by the FAA affect military use, the roles are reversed. The proponent's action officers (civil engineering and local airspace management) must ensure that the FAA is fully integrated into the airspace...

32 CFR 989.28 - Airspace and range proposals.

Code of Federal Regulations, 2012 CFR

2012-07-01

... initiated by the FAA affect military use, the roles are reversed. The proponent's action officers (civil engineering and local airspace management) must ensure that the FAA is fully integrated into the airspace...

32 CFR 989.28 - Airspace and range proposals.

Code of Federal Regulations, 2010 CFR

2010-07-01

... initiated by the FAA affect military use, the roles are reversed. The proponent's action officers (civil engineering and local airspace management) must ensure that the FAA is fully integrated into the airspace...

75 FR 23580 - Amendment of Class E Airspace; Mapleton, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-04

...-1155; Airspace Docket No. 09-ACE-14] Amendment of Class E Airspace; Mapleton, IA AGENCY: Federal... Mapleton, IA, adding additional controlled airspace to accommodate Area Navigation (RNAV) Standard Instrument Approach Procedures (SIAPs) at James G. Whiting Memorial Field Airport, Mapleton, IA. The FAA is...

75 FR 12678 - Revision of Class E Airspace; Dillingham, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-17

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-1055; Airspace Docket No. 09-AAL-16] Revision of Class E Airspace; Dillingham, AK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action revises Class E airspace at...

76 FR 73505 - Establishment of Class E Airspace; Nashville, AR

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-29

...-0497; Airspace Docket No. 11-ASW-4] Establishment of Class E Airspace; Nashville, AR AGENCY: Federal... for Nashville, AR, to accommodate new Area Navigation (RNAV) Standard Instrument Approach Procedures... a notice of proposed rulemaking to amend Class E airspace for Nashville, AR, creating additional...

76 FR 44257 - Amendment of Class E Airspace; Mobridge, SD

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-25

...-0134; Airspace Docket No. 11-AGL-3] Amendment of Class E Airspace; Mobridge, SD AGENCY: Federal... Mobridge, SD, to accommodate new Area Navigation (RNAV) Standard Instrument Approach Procedures at Mobridge... notice of proposed rulemaking to amend Class E airspace for Mobridge, SD, creating additional controlled...

76 FR 14800 - Establishment of Class E Airspace; Wolfeboro, NH

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-18

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2010-1007; Airspace Docket No. 10-ANE-109] Establishment of Class E Airspace; Wolfeboro, NH AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E Airspace...

75 FR 4269 - Establishment of Class E Airspace; Clayton, GA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-27

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-0605; Airspace Docket No. 09-ASO-19] Establishment of Class E Airspace; Clayton, GA AGENCY: Federal... September 14, 2009 that establishes Class E Airspace at Heaven's Landing Airport, Clayton, GA. DATES...

75 FR 4270 - Modification of Class E Airspace; Anniston, AL

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-27

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-0653; Airspace Docket 09-ASO-22] Modification of Class E Airspace; Anniston, AL AGENCY: Federal... October 28, 2009 that modifies the Class E airspace at Anniston Metropolitan Airport, Anniston, AL. DATES...

76 FR 9220 - Establishment of Class E Airspace; Martinsville, IN

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-17

...-1031; Airspace Docket No. 10-AGL-19] Establishment of Class E Airspace; Martinsville, IN AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action establishes Class E... Federal Register a notice of proposed rulemaking to establish Class E airspace for Martinsville, IN...

78 FR 5128 - Amendment of Class E Airspace; Savoonga, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-24

...-0323; Airspace Docket No. 12-AAL-4] Amendment of Class E Airspace; Savoonga, AK AGENCY: Federal... Savoonga, AK, to accommodate aircraft using Area Navigation (RNAV) Global Positioning System (GPS) standard... modify controlled airspace at Savoonga, AK (77 FR 61304). Interested parties were invited to participate...

Effects of enzyme supplementation on the nutrient, amino acid, and energy utilization efficiency of citrus pulp and hawthorn pulp in Linwu ducks.

PubMed

Zhang, Xu; Li, Haobang; Jiang, Guitao; Wang, Xiangrong; Huang, Xuan; Li, Chuang; Wu, Duanqin; Dai, Qiuzhong

2018-04-11

The objective of this study was to evaluate the effects of enzyme supplementation on the nutrient, amino acid, and energy utilization efficiency of citrus pulp and hawthorn pulp as unusual feedstuffs in Linwu ducks. Forty ducks were assigned to each treatment group and fed diets with or without complex enzyme supplementation. All birds received the same quantity of raw material (60 g) via the force-feeding procedure. With the exception of leucine and phenylalanine, amino acid concentrations in hawthorn pulp were twice those in citrus pulp. Enzyme supplementation significantly increased apparent dry matter digestibility (ADM) of citrus pulp (P < 0.05), but had no significant effects (P > 0.05) on the apparent and true utilization rates of other nutrients, apparent metabolizable energy (AME), or true metabolizable energy (TME), from citrus pulp and hawthorn pulp by Linwu ducks. However, enzyme supplementation significantly increased (P < 0.05) apparent gross energy, true gross energy, AME, and TME of hawthorn pulp for Linwu ducks. There were no differences in the apparent and true utilization rates of amino acids from citrus pulp (P > 0.56) between the groups, with the exception of arginine (P < 0.05). There was an increasing trend in the apparent and true utilization rates of alanine (P = 0.06) and tyrosine (P = 0.074) from citrus pulp with enzyme supplementation. The apparent and true utilization rates of threonine in hawthorn pulp were increased significantly (P < 0.05) following enzyme supplementation. The addition of exogenous enzymes improved the forage quality of citrus pulp and hawthorn pulp, which represent potential feed resources for husbandry production.

75 FR 62460 - Revocation and Establishment of Class E Airspace; Northeast Alaska, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-12

...-0445; Airspace Docket No. 10-AAL-13] Revocation and Establishment of Class E Airspace; Northeast Alaska... removes redundant Class E airspace in Northeast Alaska and establishes Class E airspace near Eagle, Alaska... proposed rulemaking in the Federal Register to remove some Class E airspace in Northeast Alaska and...

76 FR 22011 - Amendment of Class E Airspace; Carizzo Springs, Glass Ranch Airport, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-20

...-0877; Airspace Docket No. 10-ASW-13] Amendment of Class E Airspace; Carizzo Springs, Glass Ranch... amends Class E airspace for the Carizzo Springs, Glass Ranch Airport, TX, airspace area, to accommodate... rulemaking to amend Class E airspace for the Carizzo Springs, Glass Ranch Airport, TX, airspace area...

Impact of Airspace Charges on Transatlantic Aircraft Trajectories

NASA Technical Reports Server (NTRS)

Sridhar, Banavar; Ng, Hok K.; Linke, Florian; Chen, Neil Y.

2015-01-01

Aircraft flying over the airspace of different countries are subject to over-flight charges. These charges vary from country to country. Airspace charges, while necessary to support the communication, navigation and surveillance services, may lead to aircraft flying routes longer than wind-optimal routes and produce additional carbon dioxide and other gaseous emissions. This paper develops an optimal route between city pairs by modifying the cost function to include an airspace cost whenever an aircraft flies through a controlled airspace without landing or departing from that airspace. It is assumed that the aircraft will fly the trajectory at a constant cruise altitude and constant speed. The computationally efficient optimal trajectory is derived by solving a non-linear optimal control problem. The operational strategies investigated in this study for minimizing aircraft fuel burn and emissions include flying fuel-optimal routes and flying cost-optimal routes that may completely or partially reduce airspace charges en route. The results in this paper use traffic data for transatlantic flights during July 2012. The mean daily savings in over-flight charges, fuel cost and total operation cost during the period are 17.6 percent, 1.6 percent, and 2.4 percent respectively, along the cost- optimal trajectories. The transatlantic flights can potentially save $600,000 in fuel cost plus $360,000 in over-flight charges daily by flying the cost-optimal trajectories. In addition, the aircraft emissions can be potentially reduced by 2,070 metric tons each day. The airport pairs and airspace regions that have the highest potential impacts due to airspace charges are identified for possible reduction of fuel burn and aircraft emissions for the transatlantic flights. The results in the paper show that the impact of the variation in fuel price on the optimal routes is to reduce the difference between wind-optimal and cost-optimal routes as the fuel price increases. The

75 FR 27494 - Proposed Amendment of Class E Airspace; Pauls Valley, OK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-17

... 0182; Airspace Docket No. 10-ASW-4] Proposed Amendment of Class E Airspace; Pauls Valley, OK AGENCY... action proposes to amend Class E airspace at Pauls Valley, OK. Additional controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAPs) at Pauls Valley Municipal...

75 FR 64971 - Proposed Establishment of Class E Airspace; Central City, NE

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-21

...-0837; Airspace Docket No. 10-ACE-10] Proposed Establishment of Class E Airspace; Central City, NE...: This action proposes to establish Class E airspace at Central City, NE. Controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at Central City Municipal--Larry...

78 FR 48301 - Establishment of Class E Airspace; Walker, MN

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-08

...-0266; Airspace Docket No. 13-AGL-11] Establishment of Class E Airspace; Walker, MN AGENCY: Federal... at Walker, MN. Controlled airspace is necessary to accommodate new Area Navigation (RNAV) Standard Instrument Approach Procedures at Walker Municipal Airport. The FAA is taking this action to enhance the...

77 FR 68682 - Amendment of Class E Airspace; Guthrie, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-16

...-1436; Airspace Docket No. 11-ACE-29] Amendment of Class E Airspace; Guthrie, IA AGENCY: Federal... Guthrie, IA. Decommissioning of the Guthrie Center non-directional radio beacon (NDB) at Guthrie County... proposed rulemaking (NPRM) to amend Class E airspace for the Guthrie, IA, area, creating additional...

78 FR 76053 - Amendment of Class E Airspace; Chariton, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-16

...-0255; Airspace Docket No. 13-ACE-4] Amendment of Class E Airspace; Chariton, IA AGENCY: Federal... Chariton, IA. Decommissioning of the Chariton non-directional beacon (NDB) at Chariton Municipal Airport... Register a notice of proposed rulemaking (NPRM) to amend Class E airspace for the Chariton, IA, area...

75 FR 51177 - Revocation of Class E Airspace; Eastsound, WA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-19

... airspace at Orcas Island Airport, Eastsound, WA. Controlled airspace already exists in the Eastsound, WA area that accommodates the safety and management of aircraft operations at Orcas Island Airport. DATES... Regulations (14 CFR) part 71 by removing Class E surface airspace at Orcas Island Airport, Eastsound, WA...

76 FR 43575 - Amendment of Class E Airspace; Staunton, VA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-21

... airspace extending upward from 700 feet above the surface at Shenandoah Valley Regional Airport, Staunton... airspace extending upward from 700 feet above the surface to support new SIAPs developed at Shenandoah... E airspace areas extending upward from 700 feet or more above the surface of the earth...

76 FR 36285 - Establishment of Class E Airspace; Brunswick, ME

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-22

...-0116; Airspace Docket No. 11-ANE-1] Establishment of Class E Airspace; Brunswick, ME AGENCY: Federal... at Brunswick, ME, to accommodate the additional airspace needed for the Standard Instrument Approach... Executive Airport, Brunswick, ME (75 FR 14824) Docket No. FAA-2011-0116. Interested parties were invited to...

75 FR 29656 - Amendment of Class E Airspace; Magnolia, AR

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-27

...-1179; Airspace Docket No. 09-ASW-35] Amendment of Class E Airspace; Magnolia, AR AGENCY: Federal... airspace for Magnolia, AR. Decommissioning of the Magnolia non-directional beacon (NDB) at Magnolia Municipal Airport, Magnolia, AR has made this action necessary to enhance the safety and management of...

78 FR 8962 - Establishment of Class E Airspace; Kasigluk, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-07

...-0952; Airspace Docket No. 12-AAL-6] Establishment of Class E Airspace; Kasigluk, AK AGENCY: Federal... at Kasigluk, AK, to accommodate aircraft using Area Navigation (RNAV) Global Positioning System (GPS... rulemaking to modify controlled airspace at Kasigluk, AK (77 FR 60660). Interested parties were invited to...

78 FR 45849 - Amendment of Class E Airspace; Gustavus, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-30

...-0282; Airspace Docket No. 13-AAL-3] Amendment of Class E Airspace; Gustavus, AK AGENCY: Federal... Gustavus Airport, Gustavus, AK. Decommissioning of the Gustavus Nondirectional Radio Beacon (NDB) has made... Register a notice of proposed rulemaking (NPRM) to amend controlled airspace at Gustavus, AK (78 FR 31871...

77 FR 6 - Amendment of Class E Airspace; Kwigillingok, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-03

...-0881; Airspace Docket No. 11-AAL-18] Amendment of Class E Airspace; Kwigillingok, AK AGENCY: Federal... Kwigillingok, AK. The revision of two standard instrument approach procedures at the Kwigillingok Airport has... airspace at Kwigillingok, AK (76 FR 54151). Interested parties were invited to participate in this...

75 FR 65228 - Revocation of Class E Airspace; Chilicothe, MO

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-22

...-0268; Airspace Docket No. 10-ACE-2] Revocation of Class E Airspace; Chilicothe, MO AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action removes Class E airspace for Chilicothe, MO. Airport management and air traffic control facility managers have determined that the Class E...

75 FR 4270 - Establishment of Class E Airspace; Saluda, SC

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-27

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-0603; Airspace Docket No. 09-ASO-16] Establishment of Class E Airspace; Saluda, SC AGENCY: Federal... September 14, 2009 that establishes Class E Airspace at Saluda County Airport, Saluda, SC. DATES: Effective...

75 FR 4269 - Establishment of Class E Airspace; Hertford, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-27

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-0705; Airspace Docket No. 09-ASO-25] Establishment of Class E Airspace; Hertford, NC AGENCY: Federal... September 14, 2009 that establishes Class E Airspace at Harvey Point Defense Testing Activity, Hertford, NC...

75 FR 4269 - Establishment of Class E Airspace; Lewisport, KY

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-27

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-0706; Airspace Docket No. 09-ASO-26] Establishment of Class E Airspace; Lewisport, KY AGENCY: Federal... September 14, 2009 that establishes Class E Airspace at Hancock Co.--Ron Lewis Field, Lewisport, KY. DATES...

75 FR 13670 - Amendment of Class E Airspace; Gadsden, AL

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-23

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-0955; Airspace Docket No. 09-ASO-28] Amendment of Class E Airspace; Gadsden, AL AGENCY: Federal... December 29, 2009 that amends Class E airspace at Northeast Alabama Regional, Gadsden, AL. DATES: Effective...

75 FR 20773 - Establishment of Class E Airspace; Jackson, AL

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-21

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-0937; Airspace Docket No. 09-ASO-27] Establishment of Class E Airspace; Jackson, AL AGENCY: Federal... December 7, 2009 that establishes Class E airspace at Jackson Muni, Jackson, AL. DATES: Effective Date...

14 CFR 73.3 - Special use airspace.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Special use airspace. 73.3 Section 73.3 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRSPACE... defined dimensions identified by an area on the surface of the earth wherein activities must be confined...

Development of a low-cost and effective trapping device for apple maggot fly (Diptera: Tephritidae) monitoring and control in Mexican commercial hawthorn groves

USDA-ARS?s Scientific Manuscript database

Few efforts have been made in Mexico to monitor Rhagoletis pomonella (Walsh) (Diptera: Tephritidae) in commercial hawthorn (Crataegus spp.) crops. Therefore, the main objectives of this study were to evaluate infestation levels of R. pomonella in feral and commercial Mexican hawthorn and to assess ...

75 FR 63709 - Revocation of Class C Airspace, Establishment of Class D Airspace, and Modification of Class E...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-18

... foot Class E airspace at Columbus, GA. The FAA is taking this action because Columbus Metropolitan... area and the 700 foot Class E airspace area at Columbus, GA (75 FR 27670). Interested parties were... from 700 feet above the surface at Columbus, Ga. The radius of the Class E surface area at the airport...

75 FR 62461 - Revocation and Establishment of Class E Airspace; St. George, UT

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-12

...-0660; Airspace Docket No. 10-ANM-4] Revocation and Establishment of Class E Airspace; St. George, UT... Class E airspace at St. George, UT, as the airport will be closing, eliminating the need for controlled airspace. This action will establish Class E airspace for the new St. George Municipal Airport located to...

75 FR 43886 - Proposed Amendment of Class E Airspace; Corpus Christi, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-27

...-0404; Airspace Docket No. 10-ASW-7] Proposed Amendment of Class E Airspace; Corpus Christi, TX AGENCY... action proposes to amend Class E airspace in the Corpus Christi, TX area. Additional controlled airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAPs) at Corpus Christi...

78 FR 65239 - Proposed Establishment of Class E Airspace; Brevig Mission, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-31

...-0078; Airspace Docket No. 12-AAL-1] Proposed Establishment of Class E Airspace; Brevig Mission, AK...: This action proposes to establish Class E airspace at Brevig Mission Airport, Brevig Mission, AK... at Brevig Mission Airport, Brevig Mission, AK. Controlled airspace extending 2 miles north, 6 miles...

78 FR 27029 - Modification of Class C Airspace; Nashville International Airport; TN

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-09

...-0031; Airspace Docket No. 12-AWA-7] Modification of Class C Airspace; Nashville International Airport... modifies the Nashville International Airport, TN, Class C airspace area by removing a cutout from the... modify the Nashville International Airport, TN, Class C airspace area (78 FR 6257). Interested parties...

78 FR 18800 - Amendment of Class E Airspace; Decorah, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-28

...-1433; Airspace Docket No. 11-ACE-26] Amendment of Class E Airspace; Decorah, IA AGENCY: Federal... Decorah, IA. Decommissioning of the Decorah non-directional beacon (NDB) at Decorah Municipal Airport has... Register a notice of proposed rulemaking (NPRM) to amend Class E airspace for the Decorah, IA, area...

76 FR 75447 - Amendment of Class E Airspace; Centerville, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-02

...-0830; Airspace Docket No. 11-ACE-16] Amendment of Class E Airspace; Centerville, IA AGENCY: Federal... Centerville, IA. Decommissioning of the Centerville non-directional beacon (NDB) and cancellation of the NDB... Federal Register a notice of proposed rulemaking to amend Class E airspace for the Centerville, IA, area...

77 FR 42427 - Amendment of Class E Airspace; Grinnell, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-19

...-1430; Airspace Docket No. 11-ACE-23] Amendment of Class E Airspace; Grinnell, IA AGENCY: Federal... Class E airspace at Grinnell Regional Airport, Grinnell, IA, by removing reference to the Grinnell NDB... Regional Airport, Grinnell, IA, and amends the geographic coordinates of the airport to coincide with the...

76 FR 18378 - Amendment of Class E Airspace; Taylor, AZ

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-04

...-1189; Airspace Docket No. 10-AWP-19] Amendment of Class E Airspace; Taylor, AZ AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action will amend Class E airspace at Taylor Airport, Taylor, AZ, to accommodate aircraft using the CAMBO One Departure, and the Area Navigation (RNAV...

78 FR 48294 - Amendment of Class E Airspace; Mason, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-08

...-1141; Airspace Docket No. 12-ASW-12] Amendment of Class E Airspace; Mason, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at Mason, TX... Approach Procedures at Mason County Airport. This action enhances the safety and management of Instrument...

78 FR 6727 - Amendment of Class E Airspace; Lincoln, ME

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-31

...-0764; Airspace Docket No. 12-ANE-12] Amendment of Class E Airspace; Lincoln, ME AGENCY: Federal... Lincoln, ME, as the Lincoln Non-Directional Beacon (NDB) has been decommissioned and new Standard... in the Federal Register a notice of proposed rulemaking to amend Class E airspace at Lincoln, ME (77...

78 FR 72009 - Establishment of Class E Airspace; Star, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-02

...-0440; Airspace Docket No. 13-ASO-10] Establishment of Class E Airspace; Star, NC AGENCY: Federal... at Star, NC, to accommodate a new Area Navigation (RNAV) Global Positioning System (GPS) Standard... Federal Register a notice of proposed rulemaking to establish Class E airspace at Star, NC (78 FR 54413...

77 FR 4458 - Amendment of Class E Airspace; Rugby, ND

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-30

...-0433; Airspace Docket No. 11-AGL-12] Amendment of Class E Airspace; Rugby, ND AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for Rugby, ND. Decommissioning of the Rugby non-directional beacon (NDB) at Rugby Municipal Airport has made this action...

78 FR 50323 - Amendment of Class E Airspace; Lexington, OK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-19

...-0272; Airspace Docket No. 13-ASW-10] Amendment of Class E Airspace; Lexington, OK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at... Class E surface area to a Class E transition area. This action enhances the safety and management of...

78 FR 38828 - Establishment of Class E Airspace; Captiva, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-28

...-1335; Airspace Docket No. 12-ASO-19] Establishment of Class E Airspace; Captiva, FL AGENCY: Federal...: History On June 6, 2013, the FAA published a final rule, in the Federal Register establishing Class E... aeronautical data charting service, thereby making this action necessary. The Class E airspace designations are...

Influence of extraction technique on the anti-oxidative potential of hawthorn (Crataegus monogyna) extracts in bovine muscle homogenates.

PubMed

Shortle, E; O'Grady, M N; Gilroy, D; Furey, A; Quinn, N; Kerry, J P

2014-12-01

Six extracts were prepared from hawthorn (Crataegus monogyna) leaves and flowers (HLF) and berries (HB) using solid-liquid [traditional (T) (HLFT, HBT), sonicated (S) (HLFS, HBS)] and supercritical fluid (C) extraction (HLFC, HBC) techniques. The antioxidant activities of HLF and HB extracts were characterised using in vitro antioxidant assays (TPC, DPPH, FRAP) and in 25% bovine muscle (longissimus lumborum) homogenates (lipid oxidation (TBARS), oxymyoglobin (% of total myoglobin)) after 24h storage at 4°C. Hawthorn extracts exhibited varying degrees of antioxidant potency. In vitro and muscle homogenate (TBARS) antioxidant activity followed the order: HLFS>HLFT and HBT>HBS. In supercritical fluid extracts, HLFC>HBC (in vitro antioxidant activity) and HLFC≈HBC (TBARS). All extracts (except HBS) reduced oxymyoglobin oxidation. The HLFS extract had the highest antioxidant activity in all test systems. Supercritical fluid extraction (SFE) exhibited potential as a technique for the manufacture of functional ingredients (antioxidants) from hawthorn for use in muscle foods. Copyright © 2014 Elsevier Ltd. All rights reserved.

77 FR 49399 - Proposed Amendment of Class E Airspace; Forest City, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-16

...-0654; Airspace Docket No. 12-ACE-3] Proposed Amendment of Class E Airspace; Forest City, IA AGENCY... action proposes to amend Class E airspace at Forest City, IA. Additional controlled airspace is necessary... accommodate new standard instrument approach procedures at Forest City Municipal Airport, Forest City, IA. The...

77 FR 71361 - Proposed Amendment of Class E Airspace; West Union, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-30

...-1434; Airspace Docket No. 11-ACE-27] Proposed Amendment of Class E Airspace; West Union, IA AGENCY... action proposes to amend Class E airspace at West Union, IA. Decommissioning of the West Union non... instrument approach procedures at George L. Scott Municipal Airport, West Union, IA. Airspace reconfiguration...

77 FR 49712 - Amendment to Class B Airspace; Salt Lake City, UT

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-17

... operating in the vicinity of SLC. The modified Class B airspace areas were designed to ensure all instrument... final Salt Lake City Class B airspace design provides operational and safety benefits to all airspace... Salt Lake City Class B airspace design also incorporated reductions to the northern and southern...

77 FR 17363 - Proposed Establishment of Class E Airspace; West Memphis, AR

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-26

...-0155; Airspace Docket No. 12-ASW-1] Proposed Establishment of Class E Airspace; West Memphis, AR AGENCY... action proposes to establish Class E airspace at West Memphis, AR. Separation of existing Class E... surface at West Memphis, AR, to accommodate the separation of existing Class E airspace surrounding West...

78 FR 73749 - Proposed Amendment of Class D Airspace; St. Joseph, MO

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-09

...-0917; Airspace Docket No. 13-ACE-16] Proposed Amendment of Class D Airspace; St. Joseph, MO AGENCY... action proposes to amend Class D airspace at St. Joseph, MO. Additional controlled airspace is necessary... Rosecrans Municipal Airport, St. Joseph, MO. Accordingly, additional segments would extend from the 4.3-mile...

78 FR 30797 - Proposed Amendment of Class E Airspace; Point Thomson, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-23

...-1175; Airspace Docket No. 12-AAL-11] Proposed Amendment of Class E Airspace; Point Thomson, AK AGENCY... action proposes to modify the airspace at Point Thomson, AK by establishing Class E Airspace at Point Thomson Airstrip Airport, Point Thomson, AK. This will accommodate aircraft using a new Area Navigation...

76 FR 80230 - Amendment of Class D and E Airspace; Baltimore, MD

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-23

... November 28, 2011, amending controlled airspace at Martin State Airport, Baltimore, MD. DATES: Effective... published a final rule in the Federal Register amending Class D and E airspace at Martin State Airport... the airspace designation for the Class D and Class E airspace areas at Martin State Airport, Baltimore...

76 FR 49385 - Proposed Amendment of Class E Airspace; South Bend, IN

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-10

...-0250; Airspace Docket No. 11-AGL-6] Proposed Amendment of Class E Airspace; South Bend, IN AGENCY... action proposes to amend Class E airspace in the South Bend, IN area. Additional controlled airspace is... (IFR) operations for SIAPs at the airport. The geographic coordinates for South Bend Regional Airport...

78 FR 72001 - Amendment of Class D and E Airspace, and Establishment of Class E Airspace; Salisbury, MD

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-02

...'' W.) That airspace extending upward from the surface to and including 2,500 feet MSL [[Page 72002...] Salisbury-Ocean City Wicomico Regional Airport, MD (Lat. 38[deg]20'25'' N., long. 75[deg]30'34'' W.) That... (Lat. 38[deg]20'25'' N., long. 75[deg]30'34'' W.) That airspace extending upward from the surface...

75 FR 66344 - Amendment of Jet Route J-93; CA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-28

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2010-1022; Airspace Docket No. 10-AWP-4] RIN 2120-AA66 Amendment of Jet Route J-93; CA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: This action...

75 FR 51171 - Amendment of Class D and Class E Airspace; Kaneohe, HI

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-19

...; Airspace Docket No. 10-AWP-10] Amendment of Class D and Class E Airspace; Kaneohe, HI AGENCY: Federal... Class D and Class E airspace at Kaneohe Bay Marine Corps Air Station (MCAS), Kaneohe, HI. The FAA is... airspace and Class E airspace upward from 700 feet above the surface at Kaneohe Bay MCAS, Kaneohe Bay, HI...

Virtual Airspace Modeling and Simulation (VAMS) Project First Technical Interchange Meeting

NASA Technical Reports Server (NTRS)

Beard, Robert; Kille, Robert; Kirsten, Richard; Rigterink, Paul; Sielski, Henry; Gratteau, Melinda F. (Editor)

2002-01-01

A three-day NASA Virtual Airspace and Modeling Project (VAMS) Technical Interchange Meeting (TIM) was held at the NASA Ames Research Center in Mountain View, CA. on May 21 through May 23,2002. The purpose of this meeting was to share initial concept information sponsored by the VAMS Project. An overall goal of the VAMS Project is to develop validated, blended, robust and transition-able air transportation system concepts over the next five years that will achieve NASA's long-term Enterprise Aviation Capacity goals. This document describes the presentations at the TIM, their related questions and answers, and presents the TIM recommendations.

75 FR 16333 - Establishment of Class E Airspace; Quitman, GA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-01

...-0053; Airspace Docket No. 10-ASO-12] Establishment of Class E Airspace; Quitman, GA AGENCY: Federal... establishes Class E Airspace at Quitman, GA, to accommodate Standard Instrument Approach Procedures (SIAPs) at... inclusion in the Rules Docket must be received on or before May 17, 2010. The Director of the Federal...

78 FR 25382 - Amendment of Class E Airspace; Griffin, GA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-01

... County Airport, Griffin, GA (Lat. 33[deg]13'37'' N., long. 84[deg]16'30'' W.) That airspace extending...-1219; Airspace Docket No. 12-ASO-43] Amendment of Class E Airspace; Griffin, GA AGENCY: Federal... Griffin, GA, as the Griffin Non-Directional Beacon (NDB) has been decommissioned and new Standard...

75 FR 66300 - Amendment of Class E Airspace; Searcy, AR

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-28

...-1182; Airspace Docket No. 09-ASW-37] Amendment of Class E Airspace; Searcy, AR AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for Searcy, AR. Decommissioning of the Searcy non-directional beacon (NDB) at Searcy Municipal Airport, Searcy, AR, has made this...

75 FR 29654 - Amendment of Class E Airspace; Manila, AR

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-27

...-1184; Airspace Docket No. 09-ASW-39] Amendment of Class E Airspace; Manila, AR AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for Manila, AR. Decommissioning of the Manila non-directional beacon (NDB) at Manila Municipal Airport, Manila, AR has made this...

75 FR 32271 - Revision of Class E Airspace; Nenana, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-08

...-0081; Airspace Docket No. 10-AAL-3] Revision of Class E Airspace; Nenana, AK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action revises Class E airspace at Nenana, AK, to..., Federal Aviation Administration, 222 West 7th Avenue, Box 14, Anchorage, AK 99513-7587; telephone number...

75 FR 12679 - Revision of Class E Airspace; Iliamna, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-17

...-1036; Airspace Docket No. 09-AAL-17] Revision of Class E Airspace; Iliamna, AK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action revises Class E airspace at Iliamna, AK, to..., Federal Aviation Administration, 222 West 7th Avenue, Box 14, Anchorage, AK 99513-7587; telephone number...

75 FR 33165 - Revision of Class E Airspace; Galena, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-11

...-0299; Airspace Docket No. 10-AAL-9] Revision of Class E Airspace; Galena, AK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final Rule. SUMMARY: This action revises Class E airspace at Galena, AK, to...-538G, Federal Aviation Administration, 222 West 7th Avenue, Box 14, Anchorage, AK 99513-7587; telephone...

75 FR 72939 - Modification of Class E Airspace; Portland, OR

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-29

...-0719; Airspace Docket No. 10-ANM-8] Modification of Class E Airspace; Portland, OR AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action will modify existing Class E.... Class E airspace designations are published in paragraph 6005 of FAA Order 7400.9U dated August 18, 2010...

75 FR 31677 - Amendment of Class E Airspace; Austin, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-04

...-1152; Airspace Docket No. 09-ASW-31] Amendment of Class E Airspace; Austin, TX AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace for the Austin, TX... Procedures (SIAPs) at Austin Executive Airport, Austin, TX. The FAA is taking this action to enhance the...

77 FR 27666 - Proposed Amendment of Class E Airspace; Bar Harbor, ME

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-11

...-1366; Airspace Docket No. 11-ANE-13] Proposed Amendment of Class E Airspace; Bar Harbor, ME AGENCY... action proposes to amend Class E Airspace at Bar Harbor, ME, as the Surry Non-Directional Radio Beacon... Airport, Bar Harbor, ME. Airspace reconfiguration is necessary due to the decommissioning of the Surry NDB...

78 FR 52112 - Proposed Amendment of Class E Airspace; Cut Bank, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-22

...-0664; Airspace Docket No. 13-ANM-22] Proposed Amendment of Class E Airspace; Cut Bank, MT AGENCY... action proposes to modify Class E airspace at Cut Bank Municipal Airport, Cut Bank, MT. Controlled... from 700/1,200 feet above the surface at Cut Bank Municipal Airport, Cut Bank, MT. Controlled airspace...

75 FR 32652 - Revocation and Establishment of Class E Airspace; Nuiqsut, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-09

...-0502; Airspace Docket No. 10-AAL-15] Revocation and Establishment of Class E Airspace; Nuiqsut, AK... establishes Class E airspace on the north slope of Alaska near Nuiqsut, AK, to provide controlled airspace to..., Pioneer Heliport (AA27), Nuiqsut, AK, and Oooguruk Island Heliport (AK32), Nuiqsut, AK, both formerly...

Airspace Complexity and its Application in Air Traffic Management

NASA Technical Reports Server (NTRS)

Sridhar, Banavar; Chatterji, Gano; Sheth, Kapil; Edwards, Thomas (Technical Monitor)

1998-01-01

The United States Air Traffic Management (ATM) system provides services to enable safe, orderly and efficient aircraft operations within the airspace over the continental United States and over large portions of the Pacific and Atlantic Oceans, and the Gulf of Mexico. It consists of two components, Air Traffic Control (ATC) and Traffic Flow Management (TFM). The ATC function ensures that the aircraft within the airspace are separated at all times while the TFM function organizes the aircraft into a flow pattern to ensure their safe and efficient movement. In order to accomplish the ATC and TFM functions, the airspace over United States is organized into 22 Air Route Traffic Control Centers (ARTCCs). The Center airspace is stratified into low-altitude, high-altitude and super-high altitude groups of Sectors. Each vertical layer is further partitioned into several horizontal Sectors. A typical ARTCC airspace is partitioned into 20 to 80 Sectors. These Sectors are the basic control units within the ATM system.

Anti-inflammatory, gastroprotective, free-radical-scavenging, and antimicrobial activities of hawthorn berries ethanol extract.

PubMed

Tadić, Vanja M; Dobrić, Silva; Marković, Goran M; Dordević, Sofija M; Arsić, Ivana A; Menković, Nebojsa R; Stević, Tanja

2008-09-10

Hawthorn [Crataegus monogyna Jacq. and Crataegus oxyacantha L.; sin. Crataegus laevigata (Poiret) DC., Rosaceae] leaves, flowers, and berries are used in traditional medicine in the treatment of chronic heart failure, high blood pressure, arrhythmia, and various digestive ailments, as well as geriatric and antiarteriosclerosis remedies. According to European Pharmacopoeia 6.0, hawthorn berries consist of the dried false fruits of these two species or their mixture. The present study was carried out to test free-radical-scavenging, anti-inflammatory, gastroprotective, and antimicrobial activities of hawthorn berries ethanol extract. Phenolic compounds represented 3.54%, expressed as gallic acid equivalents. Determination of total flavonoid aglycones content yielded 0.18%. The percentage of hyperoside, as the main flavonol component, was 0.14%. With respect to procyanidins content, the obtained value was 0.44%. DPPH radical-scavenging capacity of the extract was concentration-dependent, with EC50 value of 52.04 microg/mL (calculation based on the total phenolic compounds content in the extract). Oral administration of investigated extract caused dose-dependent anti-inflammatory effect in a model of carrageenan-induced rat paw edema. The obtained anti-inflammatory effect was 20.8, 23.0, and 36.3% for the extract doses of 50, 100, and 200 mg/kg, respectively. In comparison to indomethacin, given in a dose producing 50% reduction of rat paw edema, the extract given in the highest tested dose (200 mg/kg) showed 72.4% of its activity. Gastroprotective activity of the extract was investigated using an ethanol-induced acute stress ulcer in rats with ranitidine as a reference drug. Hawthorn extract produced dose-dependent gastroprotective activity (3.8 +/- 2.1, 1.9 +/- 1.7, and 0.7 +/- 0.5 for doses of 50, 100, and 200 mg/kg, respectively), with the efficacy comparable to that of the reference drug. Antimicrobial testing of the extract revealed its moderate bactericidal

75 FR 32093 - Revision of Restricted Area R-2504; Camp Roberts, CA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-07

...-0557; Airspace Docket No. 10-AWP-6] RIN 2120-AA66 Revision of Restricted Area R-2504; Camp Roberts, CA... Restricted Area R-2504, Camp Roberts, CA, by subdividing the area of R-2504 to create R-2504A and R-2504B. Together, R-2504A and R-2504B will occupy the same lateral and vertical dimensions of the existing R-2504...

75 FR 62458 - Revision of Class E Airspace; Tanana, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-12

...-0588 Airspace Docket No. 10-AAL-16] Revision of Class E Airspace; Tanana, AK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action revises Class E airspace at Tanana, AK. The... West 7th Avenue, Box 14, Anchorage, AK 99513-7587; telephone number (907) 271-5898; fax: (907) 271-2850...

76 FR 66178 - Revision of Class E Airspace; Umiat, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-26

...-0750; Airspace Docket No. 11-AAL-08] Revision of Class E Airspace; Umiat, AK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action revises Class E airspace at Umiat, AK, due to...-538G, Federal Aviation Administration, 222 West 7th Avenue, Box 14, Anchorage, AK 99513-7587; telephone...

75 FR 32272 - Revision of Class E Airspace; Kaltag, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-08

...-0082; Airspace Docket No. 10-AAL-4] Revision of Class E Airspace; Kaltag, AK AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action revises Class E airspace at Kaltag, AK, to..., Anchorage, AK 99513-7587; telephone number (907) 271-5898; fax: (907) 271-2850; e-mail: [email protected

78 FR 58158 - Establishment of Class D Airspace; Bryant AAF, Anchorage, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-23

...-2012-0433; Airspace Docket No. 12-AAL-5] Establishment of Class D Airspace; Bryant AAF, Anchorage, AK... corrects a final rule published in the Federal Register August 8, 2013 that establishes Class D airspace at... Bryant AAF, in that the language indicating Class D airspace as part time was left out. DATES: Effective...

78 FR 11115 - Proposed Amendment of Class E Airspace; Atwood, KS

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-15

...-1431; Airspace Docket No. 11-ACE-24] Proposed Amendment of Class E Airspace; Atwood, KS AGENCY: Federal..., Washington, DC 20590-0001. You must identify the docket number FAA-2011-1431/Airspace Docket No. 11- ACE-24... [[Page 11116

Legal aspects of the utilization of highway airspace.

DOT National Transportation Integrated Search

1974-01-01

The report provides a general exposition of the legal implications of the utilization of the airspace above the highways of the Commonwealth, examines Virginia's legislation in this area, and suggests improvements in the form of the Model Airspace Ac...

75 FR 64972 - Proposed Revocation of Class E Airspace; Lone Star, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-21

...-0772; Airspace Docket No. 10-ASW-10] Proposed Revocation of Class E Airspace; Lone Star, TX AGENCY... action proposes to remove Class E airspace at Lone Star, TX. Abandonment of the former Lone Star Steel... need for controlled airspace in the Lone Star, TX, area. The FAA is taking this action to ensure the...

78 FR 16399 - Amendment of Class E Airspace; Unalakleet, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-15

..., AK (Lat. 63[deg]53'19'' N., long. 160[deg]47'57'' W.) That airspace within a 4.2-mile radius of.... * * * * * AAL AK E5 Unalakleet, AK [Modified] Unalakleet Airport, AK (Lat. 63[deg]53'19'' N., long. 160[deg]47...; Airspace Docket No. 12-AAL-3] Amendment of Class E Airspace; Unalakleet, AK AGENCY: Federal Aviation...

76 FR 53358 - Proposed Amendment of Class E Airspace; Centerville, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-26

...-0830; Airspace Docket No. 11-ACE-16] Proposed Amendment of Class E Airspace; Centerville, IA AGENCY... action proposes to amend Class E airspace at Centerville, IA. Decommissioning of the Centerville non... Centerville Municipal Airport, Centerville, IA. Decommissioning of the Centerville NDB and cancellation of the...

77 FR 64919 - Proposed Establishment of Class E Airspace; Princeton, KY

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-24

... Class E Airspace; Princeton, KY AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: This action proposes to establish Class E Airspace at Princeton, KY to... serving the Princeton-Caldwell County Airport. This action would enhance the safety and airspace...

78 FR 5129 - Amendment of Class E Airspace; Wilkes-Barre, PA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-24

... Wilkes-Barre, PA, creating controlled airspace to accommodate new area navigation (RNAV) Standard... Wilkes-Barre, PA, area by creating controlled airspace at Wilkes-Barre/ Wyoming Valley Airport, Wilkes... in the Wilkes-Barre, PA, area by creating controlled airspace extending upward form 700 feet above...

77 FR 64714 - Modification of Class E Airspace; Wolf Point, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-23

...-0569; Airspace Docket No. 12-ANM-17] Modification of Class E Airspace; Wolf Point, MT AGENCY: Federal... Wolf Point, MT. Controlled airspace is necessary to accommodate aircraft using Nondirectional Radio Beacon (NDB) standard instrument approach procedures at L M Clayton Airport, Wolf Point, MT. This...

76 FR 44285 - Proposed Amendment of Class E Airspace; Fayette, AL

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-25

... Class E Airspace; Fayette, AL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: This action proposes to amend Class E Airspace at Fayette, AL, as the... at Richard Arthur Field, Fayette, AL. Airspace reconfiguration is necessary due to the...

Convective drying of hawthorn fruit (Crataegus spp.): Effect of experimental parameters on drying kinetics, color, shrinkage, and rehydration capacity.

PubMed

Aral, Serdar; Beşe, Ayşe Vildan

2016-11-01

Thin layer drying characteristics and physicochemical properties of hawthorn fruit (Crataegus spp.) were investigated using a convective dryer at air temperatures 50, 60 and 70°C and air velocities of 0.5, 0.9 and 1.3m/s. The drying process of hawthorn took place in the falling rate period, and the drying time decreased with increasing air temperature and velocity. The experimental data obtained during the drying process were fitted to eleven different mathematical models. The Midilli et al.'s model was found to be the best appropriate model for explaining the drying behavior of hawthorn fruit. Effective moisture diffusion coefficients (Deff) were calculated by Fick's diffusion model and their values varied from 2.34×10(-10)m(2)/s to 2.09×10(-9)m(2)/s. An Arrhenius-type equation was applied to determine the activation energies. While the shrinkage decreased, the rehydration ratio increased with increasing air temperature and air velocity. Copyright © 2016 Elsevier Ltd. All rights reserved.

76 FR 53356 - Proposed Amendment of Class E Airspace; Greenfield, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-26

...-0846; Airspace Docket No. 11-ACE-18] Proposed Amendment of Class E Airspace; Greenfield, IA AGENCY... action proposes to amend Class E airspace at Greenfield, IA. Decommissioning of the Greenfield non-directional beacon (NDB) at Greenfield Municipal Airport, Greenfield, IA, has made this action necessary for...

78 FR 48840 - Proposed Amendment of Class E Airspace; Hampton, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-12

...-0585; Airspace Docket No. 13-ACE-7] Proposed Amendment of Class E Airspace; Hampton, IA AGENCY: Federal... proposes to amend Class E airspace at Hampton, IA. Decommissioning of the Hampton non-directional beacon... for standard instrument approach procedures at Hampton Municipal Airport, Hampton, IA. A segment would...

76 FR 56127 - Proposed Amendment of Class E Airspace; Mercury, NV

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-12

...-0894; Airspace Docket No. 11-AWP-14] Proposed Amendment of Class E Airspace; Mercury, NV AGENCY... action proposes to amend Class E airspace at Mercury, Desert Rock Airport, Mercury, NV. Decommissioning of the Mercury Non- Directional Beacon (NDB) at Mercury, Desert Rock Airport has made this action...

75 FR 65251 - Proposed Amendment of Class E Airspace; Charleston, WV

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-22

...; Airspace Docket No. 10-AEA-24) and be submitted in triplicate to the Docket Management System (see... action proposes to modify Class E Airspace at Charleston, WV, to accommodate the additional airspace needed for the holding pattern associated with the new Standard Instrument Approach Procedures (SIAPs...

77 FR 42430 - Establishment of Class E Airspace; West Memphis, AR

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-19

... Airport from the Class E airspace of Memphis International Airport, Memphis, TN, has made this action necessary to enhance the safety and management of Instrument Flight Rules (IFR) operations at the airport... airspace surrounding West Memphis Municipal Airport from the Class E airspace area of Memphis International...

78 FR 78298 - Proposed Establishment of Class E Airspace; Phoenix, AZ

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-26

...-0956; Airspace Docket No. 13-AWP-17] Proposed Establishment of Class E Airspace; Phoenix, AZ AGENCY... rulemaking (NPRM). SUMMARY: This action proposes to establish Class E airspace at the Phoenix VHF Omni-Directional Radio Range Tactical Air Navigation Aid (VORTAC), Phoenix, AZ, to facilitate vectoring of...

76 FR 28685 - Proposed Amendment of Class E Airspace; Hannibal, MO

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-18

...-0046; Airspace Docket No. 11-ACE-1] Proposed Amendment of Class E Airspace; Hannibal, MO AGENCY... action proposes to amend Class E airspace at Hannibal, MO. Decommissioning of the Hannibal non-directional beacon (NDB) at Hannibal Regional Airport, Hannibal, MO, has made this action necessary for the...

78 FR 59806 - Establishment of Class E Airspace; White Mountain, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-30

...-1185; Airspace Docket No. 12-AAL-8] Establishment of Class E Airspace; White Mountain, AK AGENCY... airspace at White Mountain Airport, White Mountain, AK, to accommodate aircraft using new Area Navigation..., Airport, White Mountain, AK (77 FR 75598). Interested parties were invited to participate in this...

78 FR 14911 - Amendment of Class E Airspace; Hot Springs, SD

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-08

...-0655; Airspace Docket No. 12-AGL-6] Amendment of Class E Airspace; Hot Springs, SD AGENCY: Federal... Springs, SD. Additional controlled airspace is necessary to accommodate new Area Navigation (RNAV) Standard Instrument Approach Procedures at Hot Springs Municipal Airport. The FAA is taking this action to...

75 FR 20774 - Establishment of Class E Airspace; Mountain City, TN

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-21

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-0061; Airspace Docket No. 09-ASO-10] Establishment of Class E Airspace; Mountain City, TN AGENCY... December 7, 2009 that establishes Class E airspace at Johnson County Airport, Mountain City, TN. DATES...

78 FR 45478 - Proposed Establishment of Class E Airspace; Salmon, ID

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-29

...-0531; Airspace Docket No. 13-ANM-20] Proposed Establishment of Class E Airspace; Salmon, ID AGENCY... action proposes to establish Class E airspace at the Salmon VHF Omni-Directional Radio Range/Distance Measuring Equipment (VOR/DME) navigation aid, Salmon, ID, to facilitate vectoring of Instrument Flight Rules...

75 FR 18402 - Amendment of Class E Airspace; North Bend, OR

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-12

...-0831; Airspace Docket No. 09-ANM-13] Amendment of Class E Airspace; North Bend, OR AGENCY: Federal... at Southwest Oregon Regional Airport, North Bend, OR, to allow aircraft at Sunnyhill Airport to... rulemaking to establish additional controlled airspace at North Bend, OR (74 FR 57616). Interested parties...

The Hawthorne Effect: a randomised, controlled trial

PubMed Central

McCarney, Rob; Warner, James; Iliffe, Steve; van Haselen, Robbert; Griffin, Mark; Fisher, Peter

2007-01-01

Background The 'Hawthorne Effect' may be an important factor affecting the generalisability of clinical research to routine practice, but has been little studied. Hawthorne Effects have been reported in previous clinical trials in dementia but to our knowledge, no attempt has been made to quantify them. Our aim was to compare minimal follow-up to intensive follow-up in participants in a placebo controlled trial of Ginkgo biloba for treating mild-moderate dementia. Methods Participants in a dementia trial were randomised to intensive follow-up (with comprehensive assessment visits at baseline and two, four and six months post randomisation) or minimal follow-up (with an abbreviated assessment at baseline and a full assessment at six months). Our primary outcomes were cognitive functioning (ADAS-Cog) and participant and carer-rated quality of life (QOL-AD). Results We recruited 176 participants, mainly through general practices. The main analysis was based on Intention to treat (ITT), with available data. In the ANCOVA model with baseline score as a co-variate, follow-up group had a significant effect on outcome at six months on the ADAS-Cog score (n = 140; mean difference = -2.018; 95%CI -3.914, -0.121; p = 0.037 favouring the intensive follow-up group), and on participant-rated quality of life score (n = 142; mean difference = -1.382; 95%CI -2.642, -0.122; p = 0.032 favouring minimal follow-up group). There was no significant difference on carer quality of life. Conclusion We found that more intensive follow-up of individuals in a placebo-controlled clinical trial of Ginkgo biloba for treating mild-moderate dementia resulted in a better outcome than minimal follow-up, as measured by their cognitive functioning. Trial registration Current controlled trials: ISRCTN45577048 PMID:17608932

77 FR 50646 - Proposed Establishment of Class D Airspace; Bryant AAF, Anchorage, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-22

...-0433; Airspace Docket No. 12-AAL-5] Proposed Establishment of Class D Airspace; Bryant AAF, Anchorage...). SUMMARY: This action proposes to establish Class D airspace at Bryant Army Airfield (AAF), Anchorage AK... 71 by establishing Class D airspace extending upward from the surface at Bryant AAF, Anchorage AK...

78 FR 57545 - Proposed Amendment of Class D Airspace; Dallas, Addison Airport, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-19

...-0749; Airspace Docket No. 13-ASW-16] Proposed Amendment of Class D Airspace; Dallas, Addison Airport... airspace ceiling at Addison Airport, Dallas, TX, is being withdrawn. Upon review, the FAA determined that the proposed rulemaking action is premature in that an existing Dallas/Fort Worth Class B airspace...

The Airspace Concepts Evaluation System Architecture and System Plant

NASA Technical Reports Server (NTRS)

Windhorst, Robert; Meyn, Larry; Manikonda, Vikram; Carlos, Patrick; Capozzi, Brian

2006-01-01

The Airspace Concepts Evaluation System is a simulation of the National Airspace System. It includes models of flights, airports, airspaces, air traffic controls, traffic flow managements, and airline operation centers operating throughout the United States. It is used to predict system delays in response to future capacity and demand scenarios and perform benefits assessments of current and future airspace technologies and operational concepts. Facilitation of these studies requires that the simulation architecture supports plug and play of different air traffic control, traffic flow management, and airline operation center models and multi-fidelity modeling of flights, airports, and airspaces. The simulation is divided into two parts that are named, borrowing from classical control theory terminology, control and plant. The control consists of air traffic control, traffic flow management, and airline operation center models, and the plant consists of flight, airport, and airspace models. The plant can run open loop, in the absence of the control. However, undesired affects, such as conflicts and over congestions in the airspaces and airports, can occur. Different controls are applied, "plug and played", to the plant. A particular control is evaluated by analyzing how well it managed conflicts and congestions. Furthermore, the terminal area plants consist of models of airports and terminal airspaces. Each model consists of a set of nodes and links which are connected by the user to form a network. Nodes model runways, fixes, taxi intersections, gates, and/or other points of interest, and links model taxiways, departure paths, and arrival paths. Metering, flow distribution, and sequencing functions can be applied at nodes. Different fidelity model of how a flight transits are can be used by links. The fidelity of the model can be adjusted by the user by either changing the complexity of the node/link network-or the way that the link models how the flights transit

77 FR 45987 - Proposed Amendment of Class E Airspace; Guthrie, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-02

...-1436; Airspace Docket No. 11-ACE-29] Proposed Amendment of Class E Airspace; Guthrie, IA AGENCY... action proposes to amend Class E airspace at Guthrie, IA. Decommissioning of the Guthrie Center non-directional radio beacon (NDB) at Guthrie County Regional Airport, Guthrie, IA, has made this action necessary...

76 FR 5471 - Amendment of Class E Airspace; La Porte, IN

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-01

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2010-1030; Airspace Docket No. 10-AGL-18] Amendment of Class E Airspace; La Porte, IN AGENCY: Federal... controlled airspace at La Porte Hospital Heliport (75 FR 68556) Docket No. FAA-2010-1030. Interested parties...

76 FR 57633 - Amendment of Class E Airspace; Miles City, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-16

...-0515; Airspace Docket No. 11-ANM-11] Amendment of Class E Airspace; Miles City, MT AGENCY: Federal... Miles City, MT, to accommodate aircraft using a new Area Navigation (RNAV) Global Positioning System... proposed rulemaking to modify controlled airspace at Miles City, MT (76 FR 41725). Interested parties were...

77 FR 21662 - Amendment of Class D Airspace; Cocoa Beach, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-11

...-0099; Airspace Docket No. 12-ASO-11] Amendment of Class D Airspace; Cocoa Beach, FL AGENCY: Federal... Class D airspace at Cape Canaveral Skid Strip, Cocoa Beach, FL, by correcting the geographic coordinates... of Cape Canaveral Skid Strip, Cocoa Beach, FL. Also, the geographic coordinates for the airport need...

76 FR 30298 - Proposed Amendment of Class E Airspace; Cocoa, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-25

...-0070; Airspace Docket No. 10-ASO-43] Proposed Amendment of Class E Airspace; Cocoa, FL AGENCY: Federal... proposes to amend Class E Airspace at Cocoa, FL, as the Merritt Island Non-Directional Beacon (NDB) has... surface to support new standard instrument approach procedures developed at Merritt Island Airport, Cocoa...

75 FR 6594 - Proposed Amendment of Class E Airspace; Osceola, AR

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

...-1183; Airspace Docket No. 09-ASW-38] Proposed Amendment of Class E Airspace; Osceola, AR AGENCY... action proposes to amend Class E airspace at Osceola, AR. Decommissioning of the Osceola non-directional beacon (NDB) at Osceola Municipal Airport, Osceola, AR, has made this action necessary for the safety and...

75 FR 65584 - Proposed Amendment of Class E Airspace; Savannah, TN

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-26

...-1047; Airspace Docket No. 10-ASO-37] Proposed Amendment of Class E Airspace; Savannah, TN AGENCY...; Telephone: 1- 800-647-5527; Fax: 202-493-2251. You must identify the Docket Number FAA-2010-1047; Airspace... the proposal. Communications should identify both docket numbers (FAA Docket No. FAA-2010-1047...

77 FR 61248 - Establishment of Class E Airspace; Deer Lodge, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-09

...-0379; Airspace Docket No. 12-ANM-7 Establishment of Class E Airspace; Deer Lodge, MT AGENCY: Federal... at Deer Lodge-City- County Airport, Deer Lodge, MT. Controlled airspace is necessary to accommodate... procedures at Deer Lodge-City-County Airport. This improves the safety and management of Instrument Flight...

78 FR 63380 - Amendment of Class E Airspace; St. George, UT

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-24

...-0600; Airspace Docket No. 13-ANM-18] Amendment of Class E Airspace; St. George, UT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Class E airspace at St. George Municipal Airport, St. George, UT, by removing the operating hours established by a Notice to...

76 FR 49387 - Proposed Amendment of Class E Airspace; Umiat, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-10

...-0750 Airspace Docket No. 11-AAL-08] Proposed Amendment of Class E Airspace; Umiat, AK AGENCY: Federal... proposes to revise Class E airspace at Umiat, AK. The cancellation of two special Instrument Approach... Operations, Federal Aviation Administration, 222 West 7th Avenue, Box 14, Anchorage, AK 99513-7587. FOR...

75 FR 77573 - Proposed Revision of Class E Airspace; Shungnak, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-13

...-1104 Airspace Docket No. 10-AAL-19] Proposed Revision of Class E Airspace; Shungnak, AK AGENCY: Federal... proposes to revise Class E airspace at Shungnak, AK. The amendment of Standard Instrument Approach... Administration, 222 West 7th Avenue, Box 14, Anchorage, AK 99513-7587. FOR FURTHER INFORMATION CONTACT: Martha...

77 FR 6 - Amendment of Class E Airspace; Galbraith Lake, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-03

...-0865; Airspace Docket No. 11-AAL-14] Amendment of Class E Airspace; Galbraith Lake, AK AGENCY: Federal... Galbraith Lake, AK. The creation of two standard instrument approach procedures at the Galbraith Lake... airspace at Galbraith Lake, AK (76 FR 54152). Interested parties were invited to participate in this...

78 FR 13843 - Proposed Amendment of Class E Airspace; Bend, OR

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-01

...-0026; Airspace Docket No. 13-ANM-3] Proposed Amendment of Class E Airspace; Bend, OR AGENCY: Federal... proposes to modify Class E airspace at Bend, OR to accommodate aircraft departing and arriving under Instrument Flight Rules (IFR) at Bend Municipal Airport. This action would enhance the safety and management...

76 FR 28888 - Revocation of Class E Airspace; Gruver Cluck Ranch Airport, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-19

...-0272; Airspace Docket No. 11-ASW-3] Revocation of Class E Airspace; Gruver Cluck Ranch Airport, TX... Class E airspace at Gruver, Cluck Ranch Airport, TX. The airport has been abandoned, thereby eliminating the need for controlled airspace in the Gruver, Cluck Ranch Airport, TX, area. The FAA is taking this...

76 FR 53353 - Proposed Amendment of Class E Airspace; Carroll, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-26

...-0845; Airspace Docket No. 11-ACE-19] Proposed Amendment of Class E Airspace; Carroll, IA AGENCY... action proposes to amend Class E airspace at Carroll, IA. Decommissioning of the Carroll non-directional beacon (NDB) at Arthur N. Neu Airport, Carroll, IA, has made this action necessary for the safety and...

78 FR 18798 - Amendment of Class E Airspace; West Union, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-28

...-1434; Airspace Docket No. 11-ACE-27] Amendment of Class E Airspace; West Union, IA AGENCY: Federal... West Union, IA. Decommissioning of the West Union non-directional beacon (NDB) at George L. Scott... Federal Register a notice of proposed rulemaking (NPRM) to amend Class E airspace for the West Union, IA...

76 FR 13505 - Amendment of Class E Airspace; La Porte, IN

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-14

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2010-1030; Airspace Docket No. 10-AGL-18] Amendment of Class E Airspace; La Porte, IN AGENCY: Federal... amending Class E airspace in the La Porte, IN area (76 FR 5471), Docket No. FAA-2010-1030. Subsequent to...

77 FR 40834 - Proposed Amendment of Class E Airspace; Dillon, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-11

... further expand the previous proposed amendment of Class E airspace extending upward from 700 feet above... an amendment of Class E airspace extending upward from 700 feet above the surface. DATES: Comments... published a NPRM to modify Class E airspace, extending upward from 700 feet or more above the surface, at...

75 FR 14381 - Amendment of Class E Airspace; Mount Airy, NC

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-25

... triplicate to the Docket Management System (see ADDRESSES section for address and phone number). You may also... proposes to amend Class E Airspace at Mount Airy, NC, to accommodate the additional airspace needed for the... enhances the safety and airspace management of Instrument Flight Rules (IFR) operations at the airport...

75 FR 43884 - Proposed Amendment of Class E Airspace; Searcy, AR

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-27

...-1182; Airspace Docket No. 09-ASW-37] Proposed Amendment of Class E Airspace; Searcy, AR AGENCY: Federal... proposes to amend Class E airspace at Searcy, AR. Decommissioning of the Searcy non-directional beacon (NDB) at Searcy Municipal Airport, Searcy, AR, has made this action necessary for the safety and management...

75 FR 77574 - Proposed Revision of Class E Airspace; Savoonga, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-13

...-1103Airspace Docket No. 10-AAL-18] Proposed Revision of Class E Airspace; Savoonga, AK AGENCY: Federal Aviation... proposes to revise Class E airspace at Savoonga, AK. The amendment of three Standard Instrument Approach... Operations, Federal Aviation Administration, 222 West 7th Avenue, Box 14, Anchorage, AK 99513-7587. FOR...

76 FR 3011 - Establishment of Class E Airspace; Port Clarence, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-19

...-0354, Airspace Docket No. 10-AAL-10] Establishment of Class E Airspace; Port Clarence, AK AGENCY... Coast Guard Station (CGS) Airport, Port Clarence, AK. The charting of this airspace has been delayed... Administration, 222 West 7th Avenue, Box 14, Anchorage, AK 99513-7587; telephone number (907) 271-5898; fax: (907...

78 FR 48303 - Establishment of Class E Airspace; Tuba City, AZ

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-08

...-2013-0147; Airspace Docket No. 13-AWP-1] Establishment of Class E Airspace; Tuba City, AZ AGENCY... airspace at the Tuba City VHF Omni-Directional Radio Range Tactical Air Navigational Aid (VORTAC), Tuba City, AZ. In that rule, an error was made in the legal description for Tuba City, identifying the...

76 FR 21832 - Proposed Revision of Class E Airspace; Yakutat, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-19

...-0244 Airspace Docket No. 11-AAL-05] Proposed Revision of Class E Airspace; Yakutat, AK AGENCY: Federal... proposes to revise Class E airspace at Yakutat, AK. The revision of eight Standard Instrument Approach... Administration, 222 West 7th Avenue, Box 14, Anchorage, AK 99513-7587. FOR FURTHER INFORMATION CONTACT: Martha...

75 FR 52484 - Proposed Removal and Amendment of Class E Airspace, Oxford, CT

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-26

... Class E airspace extending upward from 700 feet at Oxford, CT. Decommissioning of the Waterbury Non... extension to Class D airspace and amend the description of the Class E airspace extending upward 700 feet... extension to Class D and the Class E 700 foot airspace designations are published in Paragraph 6004 and 6005...

78 FR 40382 - Modification of Class D and E Airspace; Twin Falls, ID

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-05

...-0258; Airspace Docket No. 13-ANM-12] Modification of Class D and E Airspace; Twin Falls, ID AGENCY... Class D airspace, omitted from the Title in the notice of proposed rulemaking is included in this rule... were received. Subsequent to publication, the FAA found that the Class D airspace reference was omitted...

76 FR 77383 - Amendment of Class C Airspace; Palm Beach International Airport, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-13

...-0527; Airspace Docket No. 11-AWA-2] Amendment of Class C Airspace; Palm Beach International Airport, FL... action modifies the Palm Beach International Airport, FL, Class C airspace area by raising the floor of Class C airspace over Palm Beach County Park Airport. The FAA is taking this action to enhance safety...

77 FR 34208 - Amendment of Class D and Class E Airspace; Leesburg, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-11

... amends Class D and Class E airspace at Leesburg, FL, changing the airport's name to Leesburg... and public procedures under 5 U.S.C. 553(b) are unnecessary. The Class D airspace, Class E surface...-0445; Airspace Docket No. 12-ASO-27] Amendment of Class D and Class E Airspace; Leesburg, FL AGENCY...

76 FR 2799 - Amendment of Jet Route J-93; CA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-18

...; Airspace Docket No. 10-AWP-4] RIN 2120-AA66 Amendment of Jet Route J-93; CA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action amends Jet Route J-93 in California between...) to amend J-93, (75 FR 66344). Interested parties were invited to participate in this rulemaking...

76 FR 54689 - Amendment of Class E Airspace; Hawaiian Islands, HI

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-02

...; Airspace Docket No. 11-AWP-12] Amendment of Class E Airspace; Hawaiian Islands, HI AGENCY: Federal Aviation... for the Hawaiian Islands, HI. The FAA is taking this action in response to a request from the Honolulu... E airspace extending upward from 1,200 feet above the surface for the Hawaiian Islands, HI. This...

77 FR 1429 - Proposed Amendment of Class E Airspace; Springfield, CO

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-10

...-1247; Airspace Docket No. 11-ANM-24] Proposed Amendment of Class E Airspace; Springfield, CO AGENCY... received on or before February 24, 2012. ADDRESSES: Send comments on this proposal to the U.S. Department...- 1247; Airspace Docket No. 11-ANM-24, at the beginning of your comments. You may also submit comments...

77 FR 45239 - Amendment of Class E Airspace; Bar Harbor, ME

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-31

...-1366; Airspace Docket No. 11-ANE-13] Amendment of Class E Airspace; Bar Harbor, ME AGENCY: Federal... area at Bar Harbor, ME, as the Surry Non-Directional Radio Beacon (NDB) has been decommissioned and new... airspace at Bar Harbor, ME (77 FR 27666) Docket No. FAA-2011-1366. Interested parties were invited to...

78 FR 47239 - Proposed Amendment of Class E Airspace; Washington, KS

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-05

...-0584; Airspace Docket No. 13-ACE-6] Proposed Amendment of Class E Airspace; Washington, KS AGENCY.../Airspace Docket No. 13- ACE-6, at the beginning of your comments. You may also submit comments through the... No. 13-ACE-6.'' The postcard will be date/time stamped and returned to the commenter. Availability of...

76 FR 53361 - Proposed Revocation and Amendment of Class E Airspace; Olathe, KS

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-26

...-0748; Airspace Docket No. 11-ACE-13] Proposed Revocation and Amendment of Class E Airspace; Olathe, KS... docket number FAA-2011-0748/Airspace Docket No. 11- ACE-13, at the beginning of your comments. You may... No. FAA-2011-0748/ Airspace Docket No. 11-ACE-13.'' The postcard will be date/time stamped and...

75 FR 20323 - Proposed Amendment to and Establishment of Restricted Areas and Other Special Use Airspace...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-19

... Restricted Areas and Other Special Use Airspace; Razorback Range Airspace Complex, AR AGENCY: Federal... special use airspace in the Razorback Range Airspace Complex, AR. The airspace docket number in that NPRM...

78 FR 63860 - Amendment of Class D Airspace; Kwajalein Island, Marshall Islands, RMI

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-25

...This action amends the Kwajalein Island Class D airspace description by amending the geographic coordinates for Bucholz Army Airfield (AAF), Kwajalein Island, Marshall Islands, RMI. The Bucholz AAF geographic coordinates information was updated in the Kwajalein Island Class E airspace descriptions in 2011, but was inadvertently overlooked in the Kwajalein Island Class D airspace description. This action ensures the safety of aircraft operating in the Kwajalein Island airspace area. This is an administrative action and does not affect the operating requirements of the airspace.

76 FR 54148 - Proposed Amendment of Class E Airspace; Emmonak, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-31

... AK E5 Emmonak, AK [Revised] Emmonak Airport, AK (Lat. 62[deg]47'10'' N., long. 164[deg]29'27'' W...-0880 Airspace Docket No. 11-AAL-17] Proposed Amendment of Class E Airspace; Emmonak, AK AGENCY: Federal... proposes to revise Class E airspace at Emmonak, AK. The amendment of two standard instrument approach...

14 CFR 71.33 - Class A airspace areas.

Code of Federal Regulations, 2011 CFR

2011-01-01

... airspace overlying the waters within 12 nautical miles of the coast of the 48 contiguous States, from 18,000 feet MSL to and including FL600 excluding the states of Alaska and Hawaii, Santa Barbara Island... Alaska, including that airspace overlying the waters within 12 nautical miles of the coast, from 18,000...

14 CFR 71.33 - Class A airspace areas.

Code of Federal Regulations, 2013 CFR

2013-01-01

... airspace overlying the waters within 12 nautical miles of the coast of the 48 contiguous States, from 18,000 feet MSL to and including FL600 excluding the states of Alaska and Hawaii, Santa Barbara Island... Alaska, including that airspace overlying the waters within 12 nautical miles of the coast, from 18,000...

Preliminary Airspace Operations Simulations Findings Report

NASA Technical Reports Server (NTRS)

2005-01-01

Provides preliminary findings of the initial series (normal operations and contingency management) of airspace operations simulations. The key elements of this report discuss feedback from controller subjects for UAS flight above FL430. Findings provide initial evaluation of routine UAS operations above dense ARTCC airspace (ZOB), and identify areas of further research, policy direction and procedural development. This document further serves as an addendum to the detailed AOS simulation plan (Deliverable SIM001), incorporating feedback from FAA air traffic personnel and Access 5 IPTs.

76 FR 53328 - Airspace Designations; Incorporation by Reference

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-26

... proposed changes of the airspace listings in FAA Order 7400.9U in full text as proposed rule documents in the Federal Register. Likewise, all amendments of these listings were published in full text as final... the airspace listings in FAA Order 7400.9V in full text as proposed rule documents in the Federal...

77 FR 29918 - Proposed Amendment of Class E Airspace; Battle Creek, MI

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-21

... airspace is necessary to accommodate new Standard Instrument Approach Procedures (SIAP) at W. K. Kellogg.... Kellogg Airport, Battle Creek, MI. Controlled airspace is needed for the safety and management of IFR... controlled airspace at W.K. Kellogg Airport, Battle Creek, MI. Environmental Review This proposal will be...

76 FR 70920 - Proposed Amendment of Class E Airspace; Colorado Springs, CO

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-16

...-1191; Airspace Docket No. 11-ANM-21] Proposed Amendment of Class E Airspace; Colorado Springs, CO...: This action proposes to amend Class E airspace at City of Colorado Springs Municipal Airport, Colorado Springs, CO. Decommissioning of the Black Forest Tactical Air Navigation System (TACAN) has made this...

75 FR 65255 - Proposed Modification of Class E Airspace; Show Low, AZ

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-22

...-0903; Airspace Docket No. 10-AWP-16] Proposed Modification of Class E Airspace; Show Low, AZ AGENCY... action proposes to modify Class E airspace at Show Low, AZ to accommodate new Area Navigation (RNAV) Global Positioning System (GPS) Standard Instrument Approach Procedures (SIAPs) at Show Low Regional...

77 FR 50907 - Airspace Designations; Incorporation by Reference

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-23

... FAA processed all proposed changes of the airspace listings in FAA Order 7400.9V in full text as... in full text as final rules in the Federal Register. This rule reflects the periodic integration of... changes of the airspace listings in FAA Order 7400.9W in full text as proposed rule documents in the...

78 FR 52847 - Airspace Designations; Incorporation by Reference

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-27

... FAA processed all proposed changes of the airspace listings in FAA Order 7400.9W in full text as... in full text as final rules in the Federal Register. This rule reflects the periodic integration of... changes of the airspace listings in FAA Order 7400.9X in full text as proposed rule documents in the...

Development of an economic model to assess the cost-effectiveness of hawthorn extract as an adjunct treatment for heart failure in Australia.

PubMed

Ford, Emily; Adams, Jon; Graves, Nicholas

2012-01-01

An economic model was developed to evaluate the cost-effectiveness of hawthorn extract as an adjunctive treatment for heart failure in Australia. A Markov model of chronic heart failure was developed to compare the costs and outcomes of standard treatment and standard treatment with hawthorn extract. Health states were defined by the New York Heart Association (NYHA) classification system and death. For any given cycle, patients could remain in the same NYHA class, experience an improvement or deterioration in NYHA class, be hospitalised or die. Model inputs were derived from the published medical literature, and the output was quality-adjusted life years (QALYs). Probabilistic sensitivity analysis was conducted. The expected value of perfect information (EVPI) and the expected value of partial perfect information (EVPPI) were conducted to establish the value of further research and the ideal target for such research. Hawthorn extract increased costs by $1866.78 and resulted in a gain of 0.02 QALYs. The incremental cost-effectiveness ratio was $85 160.33 per QALY. The cost-effectiveness acceptability curve indicated that at a threshold of $40 000 the new treatment had a 0.29 probability of being cost-effective. The average incremental net monetary benefit (NMB) was -$1791.64, the average NMB for the standard treatment was $92 067.49, and for hawthorn extract $90 275.84. Additional research is potentially cost-effective if research is not proposed to cost more than $325 million. Utilities form the most important target parameter group for further research. Hawthorn extract is not currently considered to be cost-effective in as an adjunctive treatment for heart failure in Australia. Further research in the area of utilities is warranted.

75 FR 44727 - Proposed Revocation and Establishment of Class E Airspace; St. George, UT

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-29

...-0660; Airspace Docket No. 10-ANM-4] Proposed Revocation and Establishment of Class E Airspace; St... (NPRM). SUMMARY: This action proposes to remove Class E airspace at St. George Municipal Airport, St... also would establish Class E airspace for the new St. George Municipal Airport located to the south of...

Abundance of Apple Maggot, Rhagoletis pomonella, Across Different Areas in Central Washington, with Special Reference to Black-Fruited Hawthorns

PubMed Central

Yee, Wee L.; Klaus, Michael W.; Cha, Dong H.; Linn, Charles E.; Goughnour, Robert B.

2012-01-01

The apple maggot fly, Rhagoletis pomonella (Walsh) (Diptera: Tephritidae), infests non-commercial apple (Malus domestica (Borkh.) Borkh.) and native black-fruited hawthorns (mostly Crataegus douglasii Lindl.) in central Washington, but little has been published on the abundance of the fly in this region. In this paper, the abundance of R. pomonella across different sites near apple-growing areas in central Washington is documented in order to assess the threat of the fly to commercial apple orchards. The fly was first detected on traps in Klickitat, Yakima, and Kittitas Counties in 1981, 1995, and 1997, respectively. From 1981–2010 in Kittitas and Yakima Counties, only 0 to 4.7% of traps on apple, crabapple, and hawthorn trees were positive for flies, whereas in Klickitat County, located farther from commercial apple orchards, 0 to 41.9% of traps were positive. In 2008, in Yakima County and Goldendale in Klickitat County, 7.8% of black-fruited hawthorn trees were infested, with 0 to 0.00054 larvae per fruit. In 2010, in Kittitas and Yakima Counties and Goldendale in Klickitat County, 25.0% of C. douglasii trees were infested, with 0.00042 to 0.00248 larvae per fruit. In 2010, in a remote forested area of Klickitat County far from commercial apple orchards, 94.7% of C. douglasii trees were infested, with 0.20813 larvae per fruit. Overall results suggest R. pomonella is unlikely to develop high populations rapidly near major commercial apple-growing areas in central Washington, including in black-fruited hawthorns, increasing chances it can be kept out of commercial orchards. PMID:23451979

78 FR 18268 - Proposed Establishment of Class E Airspace; Blue Mesa, CO

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-26

...-0193; Airspace Docket No. 13-ANM-9] Proposed Establishment of Class E Airspace; Blue Mesa, CO AGENCY... action proposes to establish Class E airspace at the Blue Mesa VHF Omni-Directional Radio Range/Distance Measuring Equipment (VOR/DME), Blue Mesa, CO to facilitate vectoring of Instrument Flight Rules (IFR...

76 FR 41725 - Proposed Amendment of Class E Airspace; Miles City, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-15

... Class E Airspace; Miles City, MT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of..., Miles City, MT, to accommodate aircraft using new Area Navigation (RNAV) Global Positioning System (GPS... airspace and Class E airspace extending upward from 700 feet above the surface at Frank Wiley Field, Miles...

77 FR 41939 - Proposed Establishment of Class E Airspace; Deer Lodge, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-17

...-0379; Airspace Docket No. 12-ANM-7 Proposed Establishment of Class E Airspace; Deer Lodge, MT AGENCY... action proposes to establish Class E airspace at Deer Lodge-City-County Airport, Deer Lodge, MT... System (GPS) standard instrument approach procedures at Deer Lodge-City-County Airport, Deer Lodge, MT...

78 FR 45474 - Proposed Establishment of Class E Airspace; Cut Bank, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-29

...-0532; Airspace Docket No. 13-ANM-21] Proposed Establishment of Class E Airspace; Cut Bank, MT AGENCY... action proposes to establish Class E airspace at the Cut Bank VHF Omni-Directional Radio Range Tactical Air Navigational Aid (VORTAC) navigation aid, Cut Bank, MT, to facilitate vectoring of Instrument...

78 FR 25383 - Amendment of Class E Airspace; West Palm Beach, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-01

...-0922; Airspace Docket No. 12-ASO-38] Amendment of Class E Airspace; West Palm Beach, FL AGENCY: Federal... West Palm Beach, FL area, as new Standard Instrument Approach Procedures (SIAPs) have been developed at Palm Beach County Park Airport. Airspace reconfiguration is necessary for the continued safety and...

76 FR 64041 - Proposed Amendment of Class E Airspace; Show Low, AZ

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-17

...-1023; Airspace Docket No. 11-AWP-15] Proposed Amendment of Class E Airspace; Show Low, AZ AGENCY... action proposes to modify Class E airspace at Show Low Regional Airport, Show Low, AZ. Controlled...) standard instrument approach procedures at Show Low Regional Airport. The FAA is proposing this action to...

75 FR 17322 - Proposed Revocation of Class D and E Airspace; Big Delta, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-06

...-0083 Airspace Docket No. 10-AAL-5] Proposed Revocation of Class D and E Airspace; Big Delta, AK AGENCY... action proposes to revoke Class D and E airspace at Big Delta, AK. This airspace duplicates the... NASSIF Building at the above address. An informal docket may also be examined during normal business...

77 FR 11796 - Proposed Amendment of Class E Airspace; Rock Springs, WY

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-28

...-0131; Airspace Docket No. 12-ANM-2 Proposed Amendment of Class E Airspace; Rock Springs, WY AGENCY... action proposes to amend Class E airspace at Rock Springs-Sweetwater County Airport, Rock Springs, WY. Decommissioning of the Rock Springs Tactical Air Navigation System (TACAN) has made this action necessary for the...

75 FR 8485 - Revocation of Class D and E Airspace; Brunswick, ME

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-25

...-0981; Airspace Docket No. 09-ANE-105] Revocation of Class D and E Airspace; Brunswick, ME AGENCY... and E Airspace at Brunswick NAS Airport, Brunswick, ME, as the airport has closed and the associated... Brunswick NAS Airport in Brunswick, ME has closed in compliance with the 2005 Base Realignment and Closure...

78 FR 25227 - Proposed Amendment of Class E Airspace; Live Oak, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-30

... action proposes to amend Class E Airspace in the Live Oak, FL area, as new Standard Instrument Approach...-0001; Airspace Docket No. 12-ASO-45] Proposed Amendment of Class E Airspace; Live Oak, FL AGENCY... continued safety and management of instrument flight rules (IFR) operations for SIAPs within the Live Oak...

78 FR 45473 - Proposed Amendment of Class E Airspace; St. George, UT

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-29

...-0600; Airspace Docket No. 13-ANM-18 Proposed Amendment of Class E Airspace; St. George, UT AGENCY... action proposes to amend Class E airspace at St. George Municipal Airport, St. George, UT, by removing... aircraft operations at St. George Municipal Airport, St. George, UT. DATES: Comments must be received on or...

Capillary electrophoretic analysis of flavonoids in single-styled hawthorn (Crataegus monogyna Jacq.) ethanolic extracts.

PubMed

Urbonaviciūte, A; Jakstas, V; Kornysova, O; Janulis, V; Maruska, A

2006-04-21

Flavonoids are an important group of natural compounds, which can prevent coronary heart disease and have antioxidant properties. Hawthorn is a well known and widely used medicinal plant due to its cardiotonic activity. Previous studies refer mostly to the HPLC analysis of the flavonoids: vitexin, quercetin, hyperoside, oligomeric procyanidins, which appear to be primarily responsible for the cardiac action of the plant. Aqueous ethanolic extracts of single-styled hawthorn (Crataegus monogyna Jacq., f.: Rosaceae Juss.) leaves and sprouts were analyzed by means of capillary zone electrophoresis (CZE). Influence of vegetation period on the extract qualitative composition and flavonoids quantities was evaluated. Sample preparation by extraction using different concentration of aqueous ethanol (40-96%, v/v) and the influence of extractant composition on the recovery of flavonoids are discussed in detail. The results obtained using CZE are compared to the results of spectrophotometric and HPLC analysis of the extracts. The effect of storage conditions of extracts (solar irradiation, temperature and duration) on degradation of flavonoids was investigated.

Singing and Companionship in the Hawthorn University of the Third-Age Choir, Australia

ERIC Educational Resources Information Center

Joseph, Dawn; Southcott, Jane

2015-01-01

The international University of the Third Age (U3A) embodies the principles of lifelong learning and personal fulfilment amongst members. The research reported in this article focused on the Choir of the U3A Hawthorn, Melbourne, Australia and the benefits perceived by members undertaking this active music engagement in non-competitive choral…

Dynamic airspace configuration algorithms for next generation air transportation system

NASA Astrophysics Data System (ADS)

Wei, Jian

The National Airspace System (NAS) is under great pressure to safely and efficiently handle the record-high air traffic volume nowadays, and will face even greater challenge to keep pace with the steady increase of future air travel demand, since the air travel demand is projected to increase to two to three times the current level by 2025. The inefficiency of traffic flow management initiatives causes severe airspace congestion and frequent flight delays, which cost billions of economic losses every year. To address the increasingly severe airspace congestion and delays, the Next Generation Air Transportation System (NextGen) is proposed to transform the current static and rigid radar based system to a dynamic and flexible satellite based system. New operational concepts such as Dynamic Airspace Configuration (DAC) have been under development to allow more flexibility required to mitigate the demand-capacity imbalances in order to increase the throughput of the entire NAS. In this dissertation, we address the DAC problem in the en route and terminal airspace under the framework of NextGen. We develop a series of algorithms to facilitate the implementation of innovative concepts relevant with DAC in both the en route and terminal airspace. We also develop a performance evaluation framework for comprehensive benefit analyses on different aspects of future sector design algorithms. First, we complete a graph based sectorization algorithm for DAC in the en route airspace, which models the underlying air route network with a weighted graph, converts the sectorization problem into the graph partition problem, partitions the weighted graph with an iterative spectral bipartition method, and constructs the sectors from the partitioned graph. The algorithm uses a graph model to accurately capture the complex traffic patterns of the real flights, and generates sectors with high efficiency while evenly distributing the workload among the generated sectors. We further improve

76 FR 54152 - Proposed Amendment of Class E Airspace Galbraith Lake, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-31

..., AK [Revised] Galbraith Lake Airport, AK (Lat. 68[deg]28'47'' N., long. 149[deg]29'24'' W) That...-0865; Airspace Docket No. 11-AAL-14] Proposed Amendment of Class E Airspace Galbraith Lake, AK AGENCY... action proposes to amend Class E airspace at Galbraith Lake AK. The creation of two special instrument...

77 FR 71492 - Amendment of Area Navigation Route Q-1; CA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-03

...-1049; Airspace Docket No. 12-ANM-12] RIN 2120-AA66 Amendment of Area Navigation Route Q-1; CA AGENCY...) route Q-1. This action corrects the spelling of the TOCOS waypoint. DATES: Effective date 0901 UTC... published a final rule, technical amendment in the Federal Register amending the description of RNAV route Q...

Interaction of Airspace Partitions and Traffic Flow Management Delay with Weather

NASA Technical Reports Server (NTRS)

Lee, Hak-Tae; Chatterji, Gano B.; Palopo, Kee

2011-01-01

The interaction of partitioning the airspace and delaying flights in the presence of convective weather is explored to study how re-partitioning the airspace can help reduce congestion and delay. Three approaches with varying complexities are employed to compute the ground delays.In the first approach, an airspace partition of 335 high-altitude sectors that is based on clear weather day traffic is used. Routes are then created to avoid regions of convective weather. With traffic flow management, this approach establishes the baseline with per-flight delay of 8.4 minutes. In the second approach, traffic flow management is used to select routes and assign departure delays such that only the airport capacity constraints are met. This results in 6.7 minutes of average departure delay. The airspace is then partitioned with a specific capacity. It is shown that airspace-capacity-induced delay can be reduced to zero ata cost of 20percent more sectors for the examined scenario.

75 FR 26151 - Proposed Revision of Class E Airspace; Kulik Lake, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-11

...-0270 Airspace Docket No. 10-AAL-8] Proposed Revision of Class E Airspace; Kulik Lake, AK AGENCY... action proposes to revise Class E airspace at Kulik Lake, AK. This action would correct an error in the... Administration, 222 West 7th Avenue, Box 14, Anchorage, AK 99513-7587. FOR FURTHER INFORMATION CONTACT: Gary Rolf...

[Comparison of morphological and microscopical diagnostic characters of Hawthorn fruits (Crataegus species)].

PubMed

Gao, G Y; Feng, Y X

1995-01-01

This paper deals with studies on morphological and microscopical diagnostic characters of Chinese Hawthorn fruits. Their similarities and differences in morphological and microscopical characters among eight species of Crataegus (C. pinnatifida Bge., C. pinnatifida var. major NE Br., C. cuneata sieb. & Zuce., C. scabrifolia (Franch.) Rehd., C. hupehensis Sarg., C. kansuensis Wils, C. maximowiczii Schneid. and C. sanguinea Pall.) fruits are compared and illustrated with diagrams.

A Virtual Laboratory for Aviation and Airspace Prognostics Research

NASA Technical Reports Server (NTRS)

Kulkarni, Chetan; Gorospe, George; Teubert, Christ; Quach, Cuong C.; Hogge, Edward; Darafsheh, Kaveh

2017-01-01

Integration of Unmanned Aerial Vehicles (UAVs), autonomy, spacecraft, and other aviation technologies, in the airspace is becoming more and more complicated, and will continue to do so in the future. Inclusion of new technology and complexity into the airspace increases the importance and difficulty of safety assurance. Additionally, testing new technologies on complex aviation systems and systems of systems can be challenging, expensive, and at times unsafe when implementing real life scenarios. The application of prognostics to aviation and airspace management may produce new tools and insight into these problems. Prognostic methodology provides an estimate of the health and risks of a component, vehicle, or airspace and knowledge of how that will change over time. That measure is especially useful in safety determination, mission planning, and maintenance scheduling. In our research, we develop a live, distributed, hardware- in-the-loop Prognostics Virtual Laboratory testbed for aviation and airspace prognostics. The developed testbed will be used to validate prediction algorithms for the real-time safety monitoring of the National Airspace System (NAS) and the prediction of unsafe events. In our earlier work1 we discussed the initial Prognostics Virtual Laboratory testbed development work and related results for milestones 1 & 2. This paper describes the design, development, and testing of the integrated tested which are part of milestone 3, along with our next steps for validation of this work. Through a framework consisting of software/hardware modules and associated interface clients, the distributed testbed enables safe, accurate, and inexpensive experimentation and research into airspace and vehicle prognosis that would not have been possible otherwise. The testbed modules can be used cohesively to construct complex and relevant airspace scenarios for research. Four modules are key to this research: the virtual aircraft module which uses the X

Evidence for sample selection effect and Hawthorne effect in behavioural HIV prevention trial among young women in a rural South African community

PubMed Central

Pettifor, Audrey; Twine, Rhian; Hughes, James P; Gomez-Olive, F Xavier; Wagner, Ryan G; Sulaimon, Afolabi; Tollman, Stephen; Selin, Amanda; MacPhail, Catherine; Kahn, Kathleen

2018-01-01

Objectives We examined the potential influence of both sample selection effects and Hawthorne effects in the behavioural HIV Prevention Trial Network 068 study, designed to examine whether cash transfers conditional on school attendance reduce HIV acquisition in young South African women. We explored whether school enrolment among study participants differed from the underlying population, and whether differences existed at baseline (sample selection effect) or arose during study participation (Hawthorne effect). Methods We constructed a cohort of 3889 young women aged 11–20 years using data from the Agincourt Health and socio-Demographic Surveillance System. We compared school enrolment in 2011 (trial start) and 2015 (trial end) between those who did (n=1720) and did not (n=2169) enrol in the trial. To isolate the Hawthorne effect, we restricted the cohort to those enrolled in school in 2011. Results In 2011, trial participants were already more likely to be enrolled in school (99%) compared with non-participants (93%). However, this association was attenuated with covariate adjustment (adjusted risk difference (aRD) (95% CI): 2.9 (− 0.7 to 6.5)). Restricting to those enrolled in school in 2011, trial participants were also more likely to be enrolled in school in 2015 (aRD (95% CI): 4.9 (1.5 to 8.3)). The strength of associations increased with age. Conclusions Trial participants across both study arms were more likely to be enrolled in school than non-participants. Our findings suggest that both sample selection and Hawthorne effects may have diminished the differences in school enrolment between study arms, a plausible explanation for the null trial findings. The Hawthorne-specific findings generate hypotheses for how to structure school retention interventions to prevent HIV. PMID:29326192

Development of an economic model to assess the cost-effectiveness of hawthorn extract as an adjunct treatment for heart failure in Australia

PubMed Central

Ford, Emily; Adams, Jon; Graves, Nicholas

2012-01-01

Objective An economic model was developed to evaluate the cost-effectiveness of hawthorn extract as an adjunctive treatment for heart failure in Australia. Methods A Markov model of chronic heart failure was developed to compare the costs and outcomes of standard treatment and standard treatment with hawthorn extract. Health states were defined by the New York Heart Association (NYHA) classification system and death. For any given cycle, patients could remain in the same NYHA class, experience an improvement or deterioration in NYHA class, be hospitalised or die. Model inputs were derived from the published medical literature, and the output was quality-adjusted life years (QALYs). Probabilistic sensitivity analysis was conducted. The expected value of perfect information (EVPI) and the expected value of partial perfect information (EVPPI) were conducted to establish the value of further research and the ideal target for such research. Results Hawthorn extract increased costs by $1866.78 and resulted in a gain of 0.02 QALYs. The incremental cost-effectiveness ratio was $85 160.33 per QALY. The cost-effectiveness acceptability curve indicated that at a threshold of $40 000 the new treatment had a 0.29 probability of being cost-effective. The average incremental net monetary benefit (NMB) was −$1791.64, the average NMB for the standard treatment was $92 067.49, and for hawthorn extract $90 275.84. Additional research is potentially cost-effective if research is not proposed to cost more than $325 million. Utilities form the most important target parameter group for further research. Conclusions Hawthorn extract is not currently considered to be cost-effective in as an adjunctive treatment for heart failure in Australia. Further research in the area of utilities is warranted. PMID:22942231

77 FR 771 - Proposed Establishment of Class E Airspace; Marion, AL

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-06

...) Global Positioning System (GPS) Standard Instrument Approach Procedures at Vaiden Field. This action... airspace at Marion, AL, providing the controlled airspace required to support the new RNAV GPS standard...

Optimizing Integrated Terminal Airspace Operations Under Uncertainty

NASA Technical Reports Server (NTRS)

Bosson, Christabelle; Xue, Min; Zelinski, Shannon

2014-01-01

In the terminal airspace, integrated departures and arrivals have the potential to increase operations efficiency. Recent research has developed geneticalgorithm- based schedulers for integrated arrival and departure operations under uncertainty. This paper presents an alternate method using a machine jobshop scheduling formulation to model the integrated airspace operations. A multistage stochastic programming approach is chosen to formulate the problem and candidate solutions are obtained by solving sample average approximation problems with finite sample size. Because approximate solutions are computed, the proposed algorithm incorporates the computation of statistical bounds to estimate the optimality of the candidate solutions. A proof-ofconcept study is conducted on a baseline implementation of a simple problem considering a fleet mix of 14 aircraft evolving in a model of the Los Angeles terminal airspace. A more thorough statistical analysis is also performed to evaluate the impact of the number of scenarios considered in the sampled problem. To handle extensive sampling computations, a multithreading technique is introduced.

76 FR 55232 - Establishment of Class E Airspace; Copperhill, TN

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-07

...) Standard Instrument Approach Procedures serving Martin Campbell Field Airport. This action enhances the safety and airspace management of Instrument Flight Rules (IFR) operations within the National Airspace... Positioning System (GPS) Standard Instrument Approach Procedures developed for Martin Campbell Field Airport...

78 FR 33965 - Establishment of Class E Airspace; Immokalee-Big Cypress Airfield, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-06

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2012-1051; Airspace Docket No. 12-ASO-39] Establishment of Class E Airspace; Immokalee-Big Cypress Airfield...: History Federal Register document FAA-2012-1051, Airspace Docket No. 12- ASO-39, published May 1, 2013...

75 FR 61993 - Amendment of Class E Airspace; Kwajalein Island, Marshall Islands, RMI

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-07

...) System from the legal description of the Class E airspace areas for Kwajalein Island, Bucholz AAF... action corrects the legal descriptions for the Class E airspace areas in the vicinity of the Marshall... and Rules Group, Office of System Operations Airspace and AIM, Federal Aviation Administration, 800...

76 FR 42471 - Establishment of Class E Airspace; Brunswick, ME

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-19

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2011-0116; Airspace Docket No. 11-ANE-1] Establishment of Class E Airspace; Brunswick, ME AGENCY: Federal Aviation Administration (FAA) DOT. ACTION: Final rule; correction. SUMMARY: This action corrects the...

78 FR 32085 - Amendment of Class E Airspace; Eureka, NV

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-29

... instrument approach procedures at the airport. This improves the safety and management of Instrument Flight... aircraft using the RNAV (GPS) standard instrument approach procedures at Eureka Airport. Class E airspace...) standard instrument approach procedures at the airport. Additional controlled airspace extending upward...

76 FR 52230 - Establishment of Class E Airspace; Forest, VA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-22

... Instrument Approach Procedures serving New London Airport. This action enhances the safety and airspace management of Instrument Flight Rules (IFR) operations within the National Airspace System. DATES: Effective... to support the new RNAV GPS standard instrument approach procedures developed for New London Airport...

77 FR 34210 - Amendment of Class E Airspace; Orlando, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-11

...-0503; Airspace Docket No. 11-ASO-19] Amendment of Class E Airspace; Orlando, FL AGENCY: Federal... Orlando, FL, as new Standard Instrument Approach Procedures have been developed at Orlando Executive... coordinates of Orlando Executive Airport, Orlando International Airport, and Kissimmee Municipal Airport...

77 FR 45240 - Establishment of Class E Airspace; Quakertown, PA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-31

... at Quakertown, PA, to accommodate the new Area Navigation (RNAV) Global Positioning System (GPS) Standard Instrument Approach Procedures at Quakertown Airport. This action enhances the safety and airspace management of Instrument Flight Rules (IFR) operations within the National Airspace System. [[Page 45241...

77 FR 45241 - Establishment of Class E Airspace; Apopka, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-31

... at Apopka, FL, to accommodate the new Area Navigation (RNAV) Global Positioning System (GPS) Standard Instrument Approach Procedures at Orlando Apopka Airport. This action enhances the safety and airspace management of Instrument Flight Rules (IFR) operations within the National Airspace System. DATES: Effective...

77 FR 45240 - Establishment of Class E Airspace; Arcadia, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-31

... at Arcadia, FL, to accommodate the new Area Navigation (RNAV) Global Positioning System (GPS) Standard Instrument Approach Procedures at Arcadia Municipal Airport. This action enhances the safety and airspace management of Instrument Flight Rules (IFR) operations within the National Airspace System. DATES...

75 FR 34624 - Revocation of Class D and E Airspace; Big Delta, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-18

...-0083; Airspace Docket No. 10-AAL-5] Revocation of Class D and E Airspace; Big Delta, AK AGENCY: Federal... at Big Delta, AK, to eliminate duplicated controlled airspace serving Allen Army Airfield. The FAA is.../systemops/fs/alaskan/rulemaking/ . SUPPLEMENTARY INFORMATION: History On Tuesday April 6, 2010, the FAA...

75 FR 43885 - Proposed Amendment of Class E Airspace; Kaiser/Lake Ozark, MO

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-27

...-0604; Airspace Docket No. 10-ACE-5] Proposed Amendment of Class E Airspace; Kaiser/Lake Ozark, MO...: This action proposes to amend Class E airspace for the Kaiser/ Lake Ozark, MO, area. Additional... for the Kaiser/Lake Ozark, MO area, to accommodate SIAPs at Camdenton Memorial Airport, Camdenton, MO...

Metsulfuron spray drift reduces fruit yield of hawthorn (Crataegus monogyna L.).

PubMed

Kjaer, Christian; Strandberg, Morten; Erlandsen, Mogens

2006-03-01

This study was carried out to investigate whether spray drift of metsulfuron has a potential to negatively affect hawthorn (Crataegus monogyna) hedgerows near agricultural fields. For this purpose four doses of metsulfuron ranging from 5% to 40% of the field dose (4 g metsulfuron per hectare) were sprayed on trees in seven different hawthorn hedgerows. The actual deposition on the leaves was measured by means of a tracer (glycine). Spraying was conducted both at the bud stage and at early flowering. Leaves, flowers, green berries and mature berries were harvested and the number and weight of each were measured. The spraying at the bud stage caused a highly significant reduction in number and dry weight of berries, whereas it had no effects on leaf and flower production. The berry reduction was close to 100% at actual depositions relevant for spray drift under normal conditions. Spraying at early flowering also significantly reduced berries although the effect was smaller than for the spraying at bud stage. The early flower stage spraying caused no reduction in number and size of leaves. The possible ecological consequence is that metsulfuron spray drift from agricultural fields has a potential to reduce the amount of berries available for frugivorous birds in nearby hedgerows. A potential need for regulatory measures to reduce herbicide spray drift to hedgerows situated near agricultural fields with herbicide use is also indicated.

75 FR 20774 - Establishment of Class E Airspace; Fort A.P. Hill, VA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-21

...-0739; Airspace Docket No. 09-AEA-14] Establishment of Class E Airspace; Fort A.P. Hill, VA AGENCY... December 7, 2009 that establishes Class E airspace at Fort A.P. Hill, VA. DATES: Effective Date: 0901 UTC... Service Center, Federal Aviation Administration, P.O. Box 20636, Atlanta, Georgia 30320; telephone (404...

78 FR 34609 - Proposed Modification of Class D and E Airspace; Kenai, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-10

...-1174; Airspace Docket No. 12-AAL-12] Proposed Modification of Class D and E Airspace; Kenai, AK AGENCY... action proposes to modify Class D and E airspace at Kenai, AK, to accommodate aircraft departing and..., at Kenai Municipal Airport, Kenai, AK. Also, the geographic coordinates of the airport would be...

77 FR 45237 - Amendment of Class D and E Airspace; Fort Rucker, AL

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-31

...; Airspace Docket No. 12-ASO-30] Amendment of Class D and E Airspace; Fort Rucker, AL AGENCY: Federal... Class D and E Airspace at Fort Rucker, AL, by updating the geographic coordinates of Cairns Army Air... continued safety and management of instrument flight rules (IFR) operations within the Fort Rucker, AL...

Ethanol extract of Zhongtian hawthorn lowers serum cholesterol in mice by inhibiting transcription of 3-hydroxy-3-methylglutaryl-CoA reductase via nuclear factor-kappa B signal pathway.

PubMed

Hu, Hai-Jie; Luo, Xue-Gang; Dong, Qing-Qing; Mu, Ai; Shi, Guo-Long; Wang, Qiu-Tong; Chen, Xiao-Ying; Zhou, Hao; Zhang, Tong-Cun; Pan, Li-Wen

2016-03-01

Hawthorn is a berry-like fruit from the species of Crataegus. In China, it has another more famous name, Shan-Zha, which has been used to improve digestion as a traditional Chinese medicine or food for thousands of years. Moreover, during the last decades, hawthorn has received more attention because of its potential to treat cardiovascular diseases. However, currently, only fruits of C. pinnatifida and C. pinnatifida var. major are included as Shan-Zha in the Chinese Pharmacopoeia. In this study, our results showed that the ethanol extract of Zhongtian hawthorn, a novel grafted cultivar of C. cuneata (wild Shan-Zha), could markedly reduce body weight and levels of serum total cholesterol, triglyceride, low-density lipoprotein cholesterol, and liver cholesterol of hyperlipidemia mice. It could suppress the stimulation effect of high-fat diet on the transcription of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) and p65, and counteract the downregulation of CYP7A1 and LDLR. In addition, the results of luciferase reporter assay and Western blot showed that the transcriptional activity of HMGCR promoter was inhibited by Zhongtian hawthorn ethanol extract in a dose-dependent manner, while overexpression of p65 could reverse this transcriptional repression effect. These results suggested that Zhongtian hawthorn could provide health benefits by counteracting the high-fat diet-induced hypercholesteolemic and hyperlipidemic effects in vivo, and the mechanism underlying this event was mainly dependent on the suppressive effect of Zhongtian hawthorn ethanol extract on the transcription of HMGCR via nuclear factor-kappa B (NF-κB) signal pathway. Therefore, this novel cultivar of hawthorn cultivar which has much bigger fruits, early bearing, high yield, cold resistance, and drought resistance, might be considered as a good alternative to Shan-Zha and has great value in the food and medicine industry. In addition, to our best knowledge, this is also the first report that the

Ethanol extract of Zhongtian hawthorn lowers serum cholesterol in mice by inhibiting transcription of 3-hydroxy-3-methylglutaryl-CoA reductase via nuclear factor-kappa B signal pathway

PubMed Central

Hu, Hai-Jie; Dong, Qing-Qing; Mu, Ai; Shi, Guo-Long; Wang, Qiu-Tong; Chen, Xiao-Ying; Zhou, Hao; Zhang, Tong-Cun

2016-01-01

Hawthorn is a berry-like fruit from the species of Crataegus. In China, it has another more famous name, Shan-Zha, which has been used to improve digestion as a traditional Chinese medicine or food for thousands of years. Moreover, during the last decades, hawthorn has received more attention because of its potential to treat cardiovascular diseases. However, currently, only fruits of C. pinnatifida and C. pinnatifida var. major are included as Shan-Zha in the Chinese Pharmacopoeia. In this study, our results showed that the ethanol extract of Zhongtian hawthorn, a novel grafted cultivar of C. cuneata (wild Shan-Zha), could markedly reduce body weight and levels of serum total cholesterol, triglyceride, low-density lipoprotein cholesterol, and liver cholesterol of hyperlipidemia mice. It could suppress the stimulation effect of high-fat diet on the transcription of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) and p65, and counteract the downregulation of CYP7A1 and LDLR. In addition, the results of luciferase reporter assay and Western blot showed that the transcriptional activity of HMGCR promoter was inhibited by Zhongtian hawthorn ethanol extract in a dose-dependent manner, while overexpression of p65 could reverse this transcriptional repression effect. These results suggested that Zhongtian hawthorn could provide health benefits by counteracting the high-fat diet-induced hypercholesteolemic and hyperlipidemic effects in vivo, and the mechanism underlying this event was mainly dependent on the suppressive effect of Zhongtian hawthorn ethanol extract on the transcription of HMGCR via nuclear factor-kappa B (NF-κB) signal pathway. Therefore, this novel cultivar of hawthorn cultivar which has much bigger fruits, early bearing, high yield, cold resistance, and drought resistance, might be considered as a good alternative to Shan-Zha and has great value in the food and medicine industry. In addition, to our best knowledge, this is also the first report that the

78 FR 41837 - Establishment of Class E Airspace; Parkston, SD

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-12

... Instrument Approach Procedures at Parkston Municipal Airport. The FAA is taking this action to enhance the safety and management of Instrument Flight Rule (IFR) operations at the airport. DATES: Effective date... airspace exists to contain new standard instrument approach procedures at the airport. Controlled airspace...

76 FR 14799 - Amendment of Class E Airspace; Newport, VT

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-18

... cancellation of the NDB approach. Controlled airspace is necessary for the safety and management of IFR... Instrument Approach Procedures (SIAPs) have been developed for Newport State Airport. This action enhances the safety and airspace management of Instrument Flight Rules (IFR) operations at the airport. DATES...

75 FR 29655 - Amendment of Class E Airspace; Batesville, AR

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-27

...-1177; Airspace Docket No. 09-ASW-34] Amendment of Class E Airspace; Batesville, AR AGENCY: Federal... Batesville, AR. Decommissioning of the Independence County non-directional beacon (NDB) at Batesville Regional Airport, Batesville, AR, has made this action necessary to enhance the safety and management of...

75 FR 68416 - Establishment of Class E Airspace; Berryville, AR

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-08

...-0690; Airspace Docket No. 10-ASW-2] Establishment of Class E Airspace; Berryville, AR AGENCY: Federal... for Berryville, AR, to accommodate Area Navigation (RNAV) Standard Instrument Approach Procedures (SIAP) at Carroll County Airport, Berryville, AR. The FAA is taking this action to enhance the safety...

75 FR 30295 - Amendment of Class E Airspace; Hoquiam, WA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-01

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2009-1063; Airspace Docket No. 09-ANM-22] Amendment of Class E Airspace; Hoquiam, WA AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: This action will amend existing Class E...

78 FR 1750 - Establishment of Class E Airspace; Princeton, KY

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-09

... the safety and airspace management of Instrument Flight Rules (IFR) operations within the National Airspace System. This action also makes a minor adjustment to the geographic coordinates of the airport... action qualifies for categorical exclusion under the National Environmental Policy Act in accordance with...

78 FR 72010 - Establishment of Class E Airspace; Magee, MS

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-02

... safety and airspace management of Instrument Flight Rules (IFR) operations within the National Airspace System. This action also updates the geographic coordinates of the airport. DATES: Effective 0901 UTC.... Subsequent to publication, the FAA found an error in the geographic coordinates of Magee Municipal Airport...

78 FR 41290 - Establishment of Class E Airspace; Sanibel, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-10

... 10, 2013, establishing controlled airspace at Sanibel Island Heliport, Sanibel, FL. DATES: Effective..., Georgia 30320; telephone (404) 305-6364. SUPPLEMENTARY INFORMATION: History On June 10, 2013, the FAA published a final rule, in the Federal Register establishing Class E airspace at Sanibel Island Heliport...

Preliminary Investigation of Civil Tiltrotor in NextGen Airspace

NASA Technical Reports Server (NTRS)

Young, Larry A.; Salvano, Dan; Wright, Ken; Chung, William; Young, Ray; Miller, David; Paris, Alfanso; Gao, Huina; Cheng, Victor

2010-01-01

Presentation intro: Tiltrotor aircraft have long been envisioned as being a potentially viable means of commercial aviation transport. Preliminary results from an ongoing study into the operational and technological considerations of Civil Tiltrotor (CTR) operation in the Next Generation airspace, circa the 2025 time-frame, are presented and discussed. In particular, a fleet of CTR aircraft has been conceptually designed. The performance characteristics of this CTR fleet was subsequently translated into BADA (Base of Aircraft DAta) models that could be used as input to emulate CTR aircraft operations in the ACES and AvTerminal airspace and terminal area simulation tools. A network of nine North-Eastern corridor airports is the focus of the airspace simulation effort; the results from this airport network viII then be extrapolated to provide insights into systemic impact of CTRs on the National Airspace System (NAS). Future work will also be detailed as to attempts to model the systemic effects of noise and emissions from this fleet of new aircraft as well as assess their leveraged impact on public service missions, in time of need, such as major regional/national disaster relief efforts. The ideal outcome of this study is a set of results whereby Next Gen airspace CONOPs can be refined to reflect potential CTR capabilities and, conversely, CTR technology development efforts can be better informed as to key performance requirement thresholds needed to be met in order to successfully introduce these aircraft into civilian aviation operation.

Loss of controller-pilot voice communications in domestic en route airspace

DOT National Transportation Integrated Search

2017-02-10

With the planned implementation of ControllerPilot Data Link Communications (CPDLC) in en route airspace, information on voice communication performance in this airspace can help to predict specific benefits associated with CPDLC, identify adjustm...

78 FR 54795 - Proposed Amendment of Class D Airspace; Dallas, Addison Airport, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-06

...-0749; Airspace Docket No. 13-ASW-16] Proposed Amendment of Class D Airspace; Dallas, Addison Airport...). SUMMARY: This action proposes to amend Class D airspace at Addison Airport, Dallas, TX. Changes to air traffic flows in the Dallas-Fort Worth metropolitan area has made it necessary to lower the ceiling of the...

78 FR 76781 - Proposed Modification of Class B Airspace; Salt Lake City, UT

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-19

... City, UT AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking... City Class B airspace area by raising the floor of a small portion of Class B airspace between the Salt Lake City Class B surface area and the Hill Air Force Base (AFB) Class D airspace area. This action...

75 FR 37292 - Amendment of Class E Airspace; Cherokee, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-29

...-0085; Airspace Docket No. 10-ACE-1] Amendment of Class E Airspace; Cherokee, IA AGENCY: Federal... Cherokee, IA. Decommissioning of the Pilot Rock non-directional beacon (NDB) at Cherokee County Regional Airport, Cherokee, IA has made this action necessary to enhance the safety and management of Instrument...

76 FR 75446 - Amendment of Class E Airspace; Mercury, NV

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-02

...-0894; Airspace Docket No. 11-AWP-14] Amendment of Class E Airspace; Mercury, NV AGENCY: Federal... Mercury, Desert Rock Airport, Mercury, NV. Decommissioning of the Mercury Non-Directional Beacon (NDB) at Mercury, Desert Rock Airport has made this action necessary for the safety and management of Instrument...

75 FR 42 - Establishment of Class E Airspace; Spencer, WV

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-04

... Aviation Administration (FAA), DOT. ACTION: Direct final rule; confirmation of effective date. SUMMARY: This action confirms the effective date of a direct final rule published in the Federal Register that establishes Class E Airspace at Spencer, WV. This action enhances the safety and airspace management of Boggs...

77 FR 29873 - Establishment of Class E Airspace; Eldon, MO

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-21

... at Eldon, MO. Controlled airspace is necessary to accommodate new Area Navigation (RNAV) Standard Instrument Approach Procedures at Eldon Model Airpark. The FAA is taking this action to enhance the safety... Federal Register a notice of proposed rulemaking (NPRM) to establish Class E airspace at Eldon Model...

76 FR 59013 - Amendment of Class E Airspace; Burlington, VT

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-23

... airspace management of Instrument Flight Rules (IFR) operations within the National Airspace System. This action also makes a minor adjustment to the geographic coordinates of the airport and recognizes the name... modified for the safety and management of IFR operations at the airport. The geographic coordinates for...

77 FR 1012 - Establishment of Class E Airspace; Inverness, FL

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-09

... airspace management of Instrument Flight Rules (IFR) operations within the National Airspace System. This action also makes a minor adjustment to the geographic coordinates of the airport. DATES: Effective 0901.... Subsequent to publication, the FAA found that the geographic coordinates for Inverness Airport needed to be...

76 FR 43576 - Amendment of Class E Airspace; Hannibal, MO

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-21

...-0046; Airspace Docket No. 11-ACE-1] Amendment of Class E Airspace; Hannibal, MO AGENCY: Federal... Hannibal, MO. Decommissioning of the Hannibal non-directional beacon (NDB) at Hannibal Regional Airport, Hannibal, MO, has made this action necessary to enhance the safety and management of Instrument Flight Rule...

77 FR 6463 - Amendment of Class E Airspace; Kwigillingok, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-08

...; Airspace Docket No. 11-AAL-18] Amendment of Class E Airspace; Kwigillingok, AK AGENCY: Federal Aviation..., Kwigillingok, AK. In that rule, errors were made in the geographic coordinates and legal description for... Airport, AK. Subsequent to publication, an error was found in the latitude coordinate for Kwigillingok...

76 FR 8626 - Revision of Class E Airspace; Shungnak, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-15

...-1104; Airspace Docket No. 10-AAL-19] Revision of Class E Airspace; Shungnak, AK AGENCY: Federal... Shungnak, AK, to accommodate amended Standard Instrument Approach Procedures (SIAPs) at the Shungnak..., Box 14, Anchorage, AK 99513-7587; telephone number (907) 271-5898; fax: (907) 271-2850; e- mail...

75 FR 12676 - Establishment of Class E Airspace; Koyukuk, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-17

...-0692; Airspace Docket No. 09-AAL-13] Establishment of Class E Airspace; Koyukuk, AK AGENCY: Federal... at Koyukuk, AK, to accommodate new Area Navigation (RNAV) Standard Instrument Approach Procedures...-538G, Federal Aviation Administration, 222 West 7th Avenue, Box 14, Anchorage, AK 99513-7587; telephone...

75 FR 12677 - Establishment of Class E Airspace; Shaktoolik, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-17

...-0142; Airspace Docket No. 09-AAL-2] Establishment of Class E Airspace; Shaktoolik, AK AGENCY: Federal... at Shaktoolik, AK, to accommodate new Area Navigation (RNAV) Standard Instrument Approach Procedures...: Gary Rolf, AAL-538G, Federal Aviation Administration, 222 West 7th Avenue, Box 14, Anchorage, AK 99513...

76 FR 80230 - Amendment of Class E Airspace; Huntington, WV

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-23

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2011-1057; Airspace Docket No. 11-AEA-21] Amendment of Class E Airspace; Huntington, WV AGENCY: Federal...) Docket No. FAA-2011-1057. Interested parties were invited to participate in this rulemaking effort by...

77 FR 41259 - Modification of Class E Airspace; Plentywood, MT

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-13

... Plentywood Sher-Wood Airport, Plentywood, MT. Controlled airspace is necessary to accommodate aircraft using... Plentywood Sher-Wood Airport. This improves the safety and management of Instrument Flight Rules (IFR... modifying Class E airspace extending upward from 700 feet above the surface at Plentywood Sher-Wood Airport...

78 FR 65555 - Establishment of Class E Airspace; Salmon, ID

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-01

...-0531; Airspace Docket No. 13-ANM-20] Establishment of Class E Airspace; Salmon, ID AGENCY: Federal... at the Salmon VHF Omni-Directional Radio Range/Distance Measuring Equipment (VOR/DME) navigation aid, Salmon, ID, to facilitate vectoring of Instrument Flight Rules (IFR) aircraft under control of Salt Lake...

Patterns in diurnal airspace use by migratory landbirds along an ecological barrier.

PubMed

Peterson, Anna C; Niemi, Gerald J; Johnson, Douglas H

2015-04-01

Migratory bird populations and survival are affected by conditions experienced during migration. While many studies and conservation and management efforts focus on terrestrial stoppage and staging areas, the aerial environment through which migrants move also is subjected to anthropogenic impacts with potential consequences to migratory movement and survival. During autumn migration, the northern coastline of Lake Superior acts as an ecological barrier for many landbirds migrating out of the boreal forests of North America. From 24 observation points, we assessed the diurnal movements of birds throughout autumn migration, 2008-2010, within a 210 × 10 km coastal region along the northern coast of Lake Superior. Several raptor species showed patterns in airspace associated with topographic features such as proximity to the coastline and presence of ridgelines. Funneling movement, commonly used to describe the concentration of raptors along a migratory diversion line that either prevents or enhances migration progress, occurred only for Bald and Golden Eagles. This suggests a "leaky" migration funnel for most migratory raptors (e.g., migrating birds exiting the purported migration corridor). Passerines migrating during the late season showed more spatial and temporal structure in airspace distribution than raptors did, including funneling and an association with airspace near the coast. We conclude that (1) the diurnal use of airspace by many migratory landbirds is patterned in space and time, (2) autumn count sites situated along ecological barriers substantially underestimate the number of raptors due to "leakage" out of these concentration areas, and (3) the magnitude and structure of diurnal passerine movements in airspace have been overlooked. The heavy and structured use of airspace by migratory landbirds, especially the airspace associated with anthropogenic development (e.g., buildings, towers, turbines) necessitates a shift in focus to airspace management

Patterns in diurnal airspace use by migratory landbirds along an ecological barrier

USGS Publications Warehouse

Peterson, Anna C.; Niemi, Gerald J.; Johnson, Douglas H.

2015-01-01

Migratory bird populations and survival are affected by conditions experienced during migration. While many studies and conservation and management efforts focus on terrestrial stoppage and staging areas, the aerial environment through which migrants move also is subjected to anthropogenic impacts with potential consequences to migratory movement and survival. During autumn migration, the northern coastline of Lake Superior acts as an ecological barrier for many landbirds migrating out of the boreal forests of North America. From 24 observation points, we assessed the diurnal movements of birds throughout autumn migration, 2008-2010, within a 210 km by 10 km coastal region along the northern coast of Lake Superior. Several raptor species showed patterns in airspace associated with topographic features such as proximity to the coastline and presence of ridgelines. Funneling movement, commonly used to describe the concentration of raptors along a migratory diversion line that either prevents or enhances migration progress, occurred only for Bald and Golden Eagles. This suggests a "leaky" migration funnel for most migratory raptors (e.g., migrating birds exiting the purported migration corridor). Passerines migrating during the late season showed more spatial and temporal structure in airspace distribution than raptors, including funneling and an association with airspace near the coast. We conclude that a) the diurnal use of airspace by many migratory landbirds is patterned in space and time, b) autumn count sites situated along ecological barriers substantially underestimate the number of raptors due to 'leakage' out of these concentration areas, and c) the magnitude and structure of diurnal passerine movements in airspace have been overlooked. The heavy and structured use of airspace by migratory landbirds, especially the airspace associated with anthropogenic development (e.g., buildings, towers, turbines) necessitates a shift in focus to airspace management and

78 FR 20846 - Proposed Establishment of Class E Airspace; Leesburg, VA

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-08

... action proposes to establish Class E surface airspace at Leesburg, VA, to aid Potomac TRACON in the safe... airspace required to aid Potomac TRACON in the safe and orderly flow of air traffic at Leesburg Executive...

75 FR 44719 - Amendment and Establishment of Restricted Areas and Other Special Use Airspace, Razorback Range...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-29

... airspace needed for military aircraft to conduct medium to high altitude standoff weapon delivery profiles... existing restricted area, and amends the boundaries description of the Special Use Airspace (SUA) Hog High..., MOAs are not rulemaking airspace actions. However, since the proposed R-2402B airspace and the Hog High...

76 FR 73501 - Amendment of Class E Airspace; Carroll, IA

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-29

...-0845; Airspace Docket No. 11-ACE-19] Amendment of Class E Airspace; Carroll, IA AGENCY: Federal... Carroll, IA. Decommissioning of the Carroll non-directional beacon (NDB) at Arthur N. Neu Airport, Carroll, IA, has made this action necessary to enhance the safety and management of Instrument Flight Rule...

76 FR 8281 - Amendment to Class B Airspace; Cleveland, OH

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-14

... submissions, including comments from Aircraft Owners and Pilots Association (AOPA) and the Soaring Society of... B airspace directly over the airspace Fun Country Soaring (FCS) currently flies in and would... indicated that a soaring club would be forced to consider shutting down or relocating operations as a result...

75 FR 32269 - Revision of Class E Airspace; Wainwright, AK

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-08

...-0080; Airspace Docket No. 10-AAL-2] Revision of Class E Airspace; Wainwright, AK AGENCY: Federal... Wainwright, AK, to accommodate amended Standard Instrument Approach Procedures (SIAPs), and one new Obstacle... Administration, 222 West 7th Avenue, Box 14, Anchorage, AK 99513-7587; telephone number (907) 271-5898; fax: (907...