14th Annual Small Business Conference

DTIC Science & Technology

2010-11-18

Government Contracting, Small Business Administration 5:45 pm - 7:45 pm RECEPTION IN DISPLAY AREA 14TH ANNUAL SMALL BUSINESS CONFERENCE...as a lobbyist for a large multi-national conglomerate that included among its subsidiaries movie companies, sports teams, financial services companies...Past Performance /Small Business Participation > M.1 Basis of Award: The Government plans to award a single contract for the Fighting Trailer

44th Annual Anomalous Absorption Conference

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beg, Farhat

Conference Grant Report July 14, 2015 Submitted to the U. S. Department of Energy Attn: Dr. Sean Finnegan By the University of California, San Diego 9500 Gilman Drive La Jolla, California 92093 On behalf of the 44th Annual Anomalous Absorption Conference 8-13 June 2014, in Estes Park, Colorado Support Requested: $10,100 Amount expended: $3,216.14 Performance Period: 1 March 20 14 to 28 February 20 15 Principal Investigator Dr. Farhat Beg Center for Energy Research University of California, San Diego 9500 Gilman Drive La Jolla, California 92093-0417 858-822-1266 (telephone) 858-534-4543 (fax) fbeg@ucsd.edu Administrative Point of Contact: Brandi Pate, 858-534-0851, blpate®ucsd.edu I.more » Background The forty-fourth Anomalous Absorption Conference was held in Estes Park, Colorado from June 5-8, 2014 (aac2014.ucsd.edu). The first Anomalous Absorption Conference was held in 1971 to assemble experts in the poorly understood area of laser-plasma absorption. The goal of that conference was to address the anomalously large laser absorption seen in plasma experiments with respect to the laser absorption predicted by linear plasma theory. Great progress in this research area has been made in the decades since that first meeting, due in part to the scientific interactions that have occurred annually at this conference. Specifically, this includes the development of nonlinear laser-plasma theory and the simulation of laser interactions with plasmas. Each summer since that first meeting, this week-long conference has been held at unique locations in North America as a scientific forum for intense scientific exchanges relevant to the interaction of laser radiation with plasmas. Responsibility for organizing the conference has traditional rotated each year between the major Inertial Confinement Fusion (ICF) laboratories and universities including LANL, LLNL, LLE, UCLA UC Davis and NRL. As the conference has matured over the past four decades, its technical footprint has

Abstracts of Papers Read at Sixteenth Annual Conference on Linguistics.

ERIC Educational Resources Information Center

Macris, James, Ed.

Abstracts of 23 addresses given at the Sixteenth Annual Conference on Linguistics are presented in this report. The papers given at the conference deal with French, American English, English, Japanese, Cantonese, Latin, and Proto-Indo-European and cover a wide variety of topics, including dialectology, form classes, grammar, and semantics. The…

The Third Annual Learning Resources Conference Proceedings.

ERIC Educational Resources Information Center

Moore, Caroline, Ed.; Piercy, David R., Ed.

Presented are the proceedings of the Third Annual Learning Resources Conference which deal with current directions in educational services for the severely handicapped. The papers are divided into three topical areas, the authors' names and addresses are supplied, and support material relating to some of the papers and a resource guide are…

Annual Quality Assurance Conference Files by Tom Mancuso

EPA Pesticide Factsheets

25th Annual Quality Assurance Conference. Abstract: Learn about the NEW EPA Method 325b for Refinery Fence Line Monitoring and TO-17 Extended for Soil Gas by Tom Mancuso and Abstract: Success Using Alternate Carrier Gases for Volatile Methods

Annual Quality Assurance Conference Presentations by Michelle Misselwitz

EPA Pesticide Factsheets

25th Annual Quality Assurance Conference. Presentations: Tools I Can’t Live Without: Speed Up Method Development and Translation, Essentials for GC and GC/MS Users; Tricks of the Trade, Keeping Your GC System Up Longer for the Analysis of Pesticides

14th Annual Expeditionary Warfare Conference

DTIC Science & Technology

2009-11-19

Untitled Document 2009expedition.html[5/12/2016 8:33:22 AM] 14th ANNUAL EXPEDITIONARY WARFARE CONFERENCE “Expeditionary Warfare in a Complex Joint...WWW.NDIA.ORG/MEETINGS/0700 “Expeditionary Warfare in a Complex Joint Operating Environment” BAY POINT MARRIOTT HOTEL, PANAMA CITY, FL...Focus: The purpose of the Quadrennial Defense Review (QDR) is to determine the nation’s defense strategy and establish a defense program for

Annual Quality Assurance Conference Presentation by Mélanie Kah

EPA Pesticide Factsheets

This is the presentation from Author Melanie Kah on Nanopesticides: State of Knowledge, Environmental Fate and Implications for Exposure Assessment, presented at the annual QA conference in Dallas, Tx in October 2015

Education and debate: a manifesto for ethics and values at annual healthcare conferences

PubMed Central

Papanikitas, Andrew

2016-01-01

Abstract In this paper I discuss the ways in which the conference stream ethics and values manifested at the 2015 RCGP Annual Conference in Glasgow, and the ways in which it is planned for the 2016 RCGP Annual Conference in Harrogate. The 2015 RCGP had plenaries, oral presentations, breakout symposia, a debate, and a poster stream. I briefly discuss each in turn before offering a manifesto (a public statement of aims and proposed policy) for ethics and values at healthcare conferences. It is my hope that others will critique this, flesh it out further and even consider how ethics and values relate to conferences for healthcare workers of various specialities. A conference provides opportunities for ethics and values discussion that are potentially distinctive from any other kind of forum. Because conferences offer the potential for knowledge and attitudes to be revisited and revised, issues can be ‘unsettled’ in a way that permits different perspectives to be more fully discussed. PMID:28250844

86th Annual Georgia Public Health Association Meeting & Conference Report.

PubMed

Smith, Selina A; Abbott, Regina; Sims, Christy

2015-01-01

The 86 th annual meeting of the Georgia Public Health Association (GPHA) and joint conference with the Southern Health Association was held in Atlanta, Georgia, on April 13-14, 2015, with pre-conference (April 12 th ) and post-conference (April 14 th ) Executive Board meetings. As Georgia's leading forum for public health researchers, practitioners, and students, the annual meeting of the GPHA brings together participants from across the state to explore recent developments in the field and to exchange techniques, tools, and experiences. Historically, the GPHA conference has been held in Savannah (n=24); Jekyll Island (n=20); Atlanta (n=16); Augusta (n=4); and Gainesville (n=1). There was no annual meeting during the early years (1929-1936); during World War II (1941-1943 and 1945); and for four years during the 1980s. Between 2006 and 2010, GPHA held one-day annual meetings and business sessions with educational workshops. Several new initiatives were highlighted as part of this year's conference. These included a "move and groove" physical activity lounge, registration scholarships for students with a dedicated meet-and-greet reception, an expanded exhibit hall, presentation and approval of three resolutions (related to healthy foods at official activities and events; weapons at official activities and events; and memorials), and approval of the 2015 legislative policy positions and amended association bylaws. The theme for the conference was Advocacy in Action for Public Health . Specifically, the program addressed ensuring access to care; protecting funding for core programs, services, and infrastructure; eliminating health disparities; and addressing key public health issues important to the state of Georgia. One hundred and nine (109) abstracts were submitted for peer review; 36 were accepted for poster and 40 for workshop presentations. Four plenary sessions with keynote speakers covered the intersection between advocacy and policy, Georgia's response to the

Proceedings of the First Annual NRO-OSL/GSFC-ATS Rideshare Conference

NASA Technical Reports Server (NTRS)

Cutlip, William (Editor)

1999-01-01

This document contains the proceedings of the First Annual NRO-OSL/GSFC-ATS Rideshare Conference. The conference was held April 16-16, 1999, at the Litton/TASC Facility, Dulles, Virginia, and was co-chaired by William Cutlip, Goddard Space Flight Center Access to Space Group, and Jim Liller, National Reconnaissance Office, Office of Space Launch.

A Circle of Colleagues Meet in the Loop: ALA Midwinter Report.

ERIC Educational Resources Information Center

Wilson Library Bulletin, 1987

1987-01-01

Highlights the American Library Association (ALA) 1987 Midwinter Conference, including the aftermath of the Attorney General's report on pornography; Congressional pay equity bills; library copying rights; federal librarians' decline in membership and privatization; public library planning, role setting, and output measures manuals; and summaries…

Annual Staff Conference of the Regina Public Library.

ERIC Educational Resources Information Center

Pasick, Adele

This transcript of a presentation at the 1977 annual staff conference of the Regina Public Library discusses a children's services study conducted during the year and places it in the context of the total services of the library. Results of over 600 interviews with children concerning library use, television viewing habits, and differences between…

IBC’s 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics International Conferences and the 2012 Annual Meeting of The Antibody Society

PubMed Central

Klöhn, Peter-Christian; Wuellner, Ulrich; Zizlsperger, Nora; Zhou, Yu; Tavares, Daniel; Berger, Sven; Zettlitz, Kirstin A.; Proetzel, Gabriele; Yong, May; Begent, Richard H.J.; Reichert, Janice M

2013-01-01

The 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics international conferences, and the 2012 Annual Meeting of The Antibody Society, organized by IBC Life Sciences with contributions from The Antibody Society and two Scientific Advisory Boards, were held December 3–6, 2012 in San Diego, CA. The meeting drew over 800 participants who attended sessions on a wide variety of topics relevant to antibody research and development. As a prelude to the main events, a pre-conference workshop held on December 2, 2012 focused on intellectual property issues that impact antibody engineering. The Antibody Engineering Conference was composed of six sessions held December 3–5, 2012: (1) From Receptor Biology to Therapy; (2) Antibodies in a Complex Environment; (3) Antibody Targeted CNS Therapy: Beyond the Blood Brain Barrier; (4) Deep Sequencing in B Cell Biology and Antibody Libraries; (5) Systems Medicine in the Development of Antibody Therapies/Systematic Validation of Novel Antibody Targets; and (6) Antibody Activity and Animal Models. The Antibody Therapeutics conference comprised four sessions held December 4–5, 2012: (1) Clinical and Preclinical Updates of Antibody-Drug Conjugates; (2) Multifunctional Antibodies and Antibody Combinations: Clinical Focus; (3) Development Status of Immunomodulatory Therapeutic Antibodies; and (4) Modulating the Half-Life of Antibody Therapeutics. The Antibody Society’s special session on applications for recording and sharing data based on GIATE was held on December 5, 2012, and the conferences concluded with two combined sessions on December 5–6, 2012: (1) Development Status of Early Stage Therapeutic Antibodies; and (2) Immunomodulatory Antibodies for Cancer Therapy. PMID:23575266

Towards Understanding the Tandem Mass Spectra of Protonated Oligopeptides. 2: The Proline Effect in Collision-Induced Dissociation of Protonated Ala-Ala-Xxx-Pro-Ala (Xxx = Ala, Ser, Leu, Val, Phe, and Trp)

NASA Astrophysics Data System (ADS)

Bleiholder, Christian; Suhai, Sándor; Harrison, Alex G.; Paizs, Béla

2011-06-01

The product ion spectra of proline-containing peptides are commonly dominated by y n ions generated by cleavage at the N-terminal side of proline residues. This proline effect is investigated in the current work by collision-induced dissociation (CID) of protonated Ala-Ala-Xxx-Pro-Ala (Xxx includes Ala, Ser, Leu, Val, Phe, and Trp) in an electrospray/quadrupole/time-of-flight (QqTOF) mass spectrometer and by quantum chemical calculations on protonated Ala-Ala-Ala-Pro-Ala. The CID spectra of all investigated peptides show a dominant y 2 ion (Pro-Ala sequence). Our computational results show that the proline effect mainly arises from the particularly low threshold energy for the amide bond cleavage N-terminal to the proline residue, and from the high proton affinity of the proline-containing C-terminal fragment produced by this cleavage. These theoretical results are qualitatively supported by the experimentally observed y 2 / b 3 abundance ratios for protonated Ala-Ala-Xxx-Pro-Ala (Xxx = Ala, Ser, Leu, Val, Phe, and Trp). In the post-cleavage phase of fragmentation the N-terminal oxazolone fragment with the Ala-Ala-Xxx sequence and Pro-Ala compete for the ionizing proton for these peptides. As the proton affinity of the oxazolone fragment increases, the y 2 / b 3 abundance ratio decreases.

Towards understanding the tandem mass spectra of protonated oligopeptides. 2: The proline effect in collision-induced dissociation of protonated Ala-Ala-Xxx-Pro-Ala (Xxx = Ala, Ser, Leu, Val, Phe, and Trp).

PubMed

Bleiholder, Christian; Suhai, Sándor; Harrison, Alex G; Paizs, Béla

2011-06-01

The product ion spectra of proline-containing peptides are commonly dominated by y(n) ions generated by cleavage at the N-terminal side of proline residues. This proline effect is investigated in the current work by collision-induced dissociation (CID) of protonated Ala-Ala-Xxx-Pro-Ala (Xxx includes Ala, Ser, Leu, Val, Phe, and Trp) in an electrospray/quadrupole/time-of-flight (QqTOF) mass spectrometer and by quantum chemical calculations on protonated Ala-Ala-Ala-Pro-Ala. The CID spectra of all investigated peptides show a dominant y(2) ion (Pro-Ala sequence). Our computational results show that the proline effect mainly arises from the particularly low threshold energy for the amide bond cleavage N-terminal to the proline residue, and from the high proton affinity of the proline-containing C-terminal fragment produced by this cleavage. These theoretical results are qualitatively supported by the experimentally observed y(2)/b(3) abundance ratios for protonated Ala-Ala-Xxx-Pro-Ala (Xxx = Ala, Ser, Leu, Val, Phe, and Trp). In the post-cleavage phase of fragmentation the N-terminal oxazolone fragment with the Ala-Ala-Xxx sequence and Pro-Ala compete for the ionizing proton for these peptides. As the proton affinity of the oxazolone fragment increases, the y(2)/b(3) abundance ratio decreases.

Annual Quality Assurance Conference Presentations by Glynda Smith and Carrie Miller

EPA Pesticide Factsheets

25th Annual Quality Assurance Conference Presentation: Disinfectants/Disinfection Byproducts –Rules and Requirements and Presentation: Long Term 2 Enhanced Surface Water Treatment Rule (LT2) Cryptosporidium Monitoring

Shifting with the Paradigm: LJ's Picks & Pans for ALA in Disneyland

ERIC Educational Resources Information Center

Berry, John N., III

2008-01-01

The feelings of librarians planning for the American Library Association (ALA) conference at Disneyland (aka Anaheim, California, June 26-July 2) range from moderate pleasure to dread. Some remember the joys and difficulties of Orlando, especially the exorbitant cab fares and mediocre restaurants. Others quail at screaming kids and tourists in…

Special report: FAA's third annual commercial space transportation forecast conference (February 8-9 2000)

DOT National Transportation Integrated Search

2000-02-01

The Third Annual Federal Aviation Administration (FAA) Commercial Space : Transportation Forecast Conference took place in Arlington, Virginia at the Sheraton National Hotel. The year 2000 conference featured seven panels and several special presenta...

Advocacy in Action: Annual 2006 DPI/NGO Conference at the United Nations

ERIC Educational Resources Information Center

Brown, Nancy

2007-01-01

The Association for Childhood Education International (ACEI) was again represented at the annual 2006 DPI/NGO conference, along with 1,600 participants from around the world. The mood this year was somber and quite serious, possibly in response to the uncertainty created by the Middle East crisis that was raging while the conference was taking…

The Seventh Annual National Conference of Black Physics Students

NASA Technical Reports Server (NTRS)

Crawley, Gerard M.

1993-01-01

The National Conference of Black Physics Students began in 1986 when several Black physics graduate students at MIT and Harvard decided to address the 'pipeline problem' of African Americans in physics by organizing a conference for Black physics undergraduates. The goals of the conference were: (1) to develop a network within the Black physics community, (2) to make Black students in physics, particularly at graduate level, aware of academic and professional opportunities and (3) to bring important issues and developments in the field to the attention of these students. We are pleased to announce the Seventh Annual National Conference of Black Physics Students held February 12 and 13, 1993 served the largest population of students so far. The largest conference previous to this one hosted 150 students. We registered and prepared for 240 students with 210 actually attenting. We received so many qualified abstracts for technical talks by students that instead of NCBPS's tradition of 3-4 student presentations, we ran 4 parallel sessions in different rooms with 4-5 presentations in each room. In response to comments from previous conferences, the program contained 3 workshop/discussion sessions. The topics for the interactive discussion workshops were: 'Getting Ready for Graduate School,' 'How to Succeed in Graduate School,' and 'Issues Facing Black Scientists.'

The Third Annual NASA Science Internet User Working Group Conference

NASA Technical Reports Server (NTRS)

Lev, Brian S. (Editor); Gary, J. Patrick (Editor)

1993-01-01

The NASA Science Internet (NSI) User Support Office (USO) sponsored the Third Annual NSI User Working Group (NSIUWG) Conference March 30 through April 3, 1992, in Greenbelt, MD. Approximately 130 NSI users attended to learn more about the NSI, hear from projects which use NSI, and receive updates about new networking technologies and services. This report contains material relevant to the conference; copies of the agenda, meeting summaries, presentations, and descriptions of exhibitors. Plenary sessions featured a variety of speakers, including NSI project management, scientists, and NSI user project managers whose projects and applications effectively use NSI, and notable citizens of the larger Internet community. The conference also included exhibits of advanced networking applications; tutorials on internetworking, computer security, and networking technologies; and user subgroup meetings on the future direction of the conference, networking, and user services and applications.

International Society for the Social Studies Annual Conference Proceedings (Orlando, Florida, February 25-26, 2010). Volume 2010, Issue 1

ERIC Educational Resources Information Center

Russell, William Benedict, III, Ed.

2010-01-01

The "ISSS Annual Conference Proceedings" is a peer-reviewed professional publication published once a year following the annual conference. (Individual papers contain references.) [For the 2009 proceedings, see ED504973.

Annual Quality Assurance Conference Files by Nicola Watson and Rui Li

EPA Pesticide Factsheets

26th Annual Quality Assurance Conference. Abstract: An Innovative Water Management Device for Online and Canister-based Thermal Desorption of Trace-level VVOCs in High Humidity Ambient Air by Nicola Watson and Rui Li

The Virtual Extension Annual Conference: Addressing Contemporary Professional Development Needs

ERIC Educational Resources Information Center

Franz, Nancy K.; Brekke, Robin; Coates, Deb; Kress, Cathann; Hlas, Julie

2014-01-01

Extension systems are experimenting with new models for conducting professional development to enhance staff competence and other returns on professional development investments. The ISUEO virtual annual conference provides a successful flipped classroom model of asynchronous and synchronous learning events for conducting an Extension annual…

Materials Presented at the MU-SPIN Ninth Annual Users' Conference

NASA Technical Reports Server (NTRS)

Harrington, James, Jr.; Brown, Robin L.

2000-01-01

MU-SPIN's Ninth Annual Users' Conference was held from September 21-25, 1999, and hosted by Florida International University, a predominantly Hispanic-serving institution located in Miami, Florida. Its theme was A New MU-SPIN for the New Millennium. The MU-SPIN conference focused on showcasing successful experiences with information technology to enhance faculty and student development in areas of scientific and technical research and education. And, it provided a forum for discussing increased participation of MU-SPIN schools in NASA Flight Missions and NASA Educational and Public Outreach activities.

The International Society for the Social Studies Annual Conference Proceedings (Orlando, Florida, February 24-25, 2011). Volume 2011, Issue 1

ERIC Educational Resources Information Center

Russell, William Benedict, III, Ed.

2011-01-01

The "ISSS Annual Conference Proceedings" is a peer-reviewed professional publication published once a year following the annual conference. (Individual papers contain references.) [For the 2010 proceedings, see ED509647.

A Look Back at ASE Annual Meetings/Conferences, 1963-2012

ERIC Educational Resources Information Center

Ramsden, Phil; Ling, Jonathan; Broadbridge, Norma

2013-01-01

Viewed by someone with no involvement, the Association for Science Education (ASE) Annual Conference will seem like an impossibly ambitious task, relying significantly on volunteers (though increasingly supported by a small permanent staff) to organise and run it. Developed from events already established in the former associations, it offers a…

Materials Presented at the MU-SPIN Tenth Annual Users' Conference

NASA Technical Reports Server (NTRS)

Harrington, James L., Jr.; Shukla, Pooja

2000-01-01

The Minority University-Space Interdisciplinary Network (MU-SPIN) Program and NASA's Minority University Research and Education Division (MURED) both reached their 10th anniversaries. In honor of this occasion, the 2000 Annual Users' Conference held at Morris Brown College in Atlanta, Georgia, September 11-15, 2000, was the first to be jointly hosted by MU-SPIN and MURED. With the theme 'Celebrating Our Tenth Year With Our Eyes on the Prize,' the conference provided a national forum for showcasing successful MU-SPIN and MURED Program (MUREP) experiences to enhance faculty/student development in areas of scientific and technical research and education.

Proceedings of the 28th Annual Farmingdale State College Teaching of Psychology: Ideas and Innovations Conference

ERIC Educational Resources Information Center

Howell-Carter, Marya, Ed.; Gonder, Jennifer, Ed.

2014-01-01

Proceedings of the 28th Annual Conference on the Teaching of Psychology: Ideas and Innovations, sponsored by the Psychology Department of Farmingdale State College. The conference theme for 2014 was:" Infusing Issues of Racial, Religious, and Sexuality Diversity Across the Undergraduate Curriculum." The Conference featured a keynote…

Engineering an ATP-dependent D-Ala:D-Ala ligase for synthesizing amino acid amides from amino acids.

PubMed

Miki, Yuta; Okazaki, Seiji; Asano, Yasuhisa

2017-05-01

We successfully engineered a new enzyme that catalyzes the formation of D-Ala amide (D-AlaNH 2 ) from D-Ala by modifying ATP-dependent D-Ala:D-Ala ligase (EC 6.3.2.4) from Thermus thermophilus, which catalyzes the formation of D-Ala-D-Ala from two molecules of D-Ala. The new enzyme was created by the replacement of the Ser293 residue with acidic amino acids, as it was speculated to bind to the second D-Ala of D-Ala-D-Ala. In addition, a replacement of the position with Glu performed better than that with Asp with regards to specificity for D-AlaNH 2 production. The S293E variant, which was selected as the best enzyme for D-AlaNH 2 production, exhibited an optimal activity at pH 9.0 and 40 °C for D-AlaNH 2 production. The apparent K m values of this variant for D-Ala and NH 3 were 7.35 mM and 1.58 M, respectively. The S293E variant could catalyze the synthesis of 9.3 and 35.7 mM of D-AlaNH 2 from 10 and 50 mM D-Ala and 3 M NH 4 Cl with conversion yields of 93 and 71.4 %, respectively. This is the first report showing the enzymatic formation of amino acid amides from amino acids.

Expression Levels of ALA Dehydratase as a Marker of ALA-PDT Efficacy

NASA Astrophysics Data System (ADS)

Avital, Schauder; Tamar, Feuerstein; Zvi, Malik

2010-05-01

Accelerated synthesis of protoporphyrinIX (PpIX) following ALA pre-treatment followed by light irradiation is the principle of ALA-PDT. Several limiting enzymes were suggested to control PpIX accumulation and PDT efficacy, among them porphobilinogen deaminase (PBGD) and ferrochelatase. Here we reveal the centrality of ALA dehydratase (ALAD) activity in predicting ALA-PDT efficacy. Silencing of ALAD expression and activity was carried out in leukemic cells using shRNA plasmid transfection or Pb2+ intoxication. ALAD activity, porphyrin synthesis and mitochondrial activity were determined versus PDT efficacy. In K562 ALAD-silenced cells, ALAD activity and expression were reduced and as a result, PpIX synthesis was almost abolished. Following ALA treatment and irradiation, ALAD-silenced cells depicted normal mitochondrial activity, in contrast to control and non-silencing transfected cells where accumulated PpIX and irradiation caused ROS formation and mitochondrial damage. Morphological analysis by scanning electron microscopy (SEM) of ALA-PDT treated cells showed no morphological changes in ALAD-silenced cells, while controls exhibited cell deformations and lysis. Annexin V-FITC/PI staining as well as LDH-L leakage testing showed that membrane integrity was undamaged following ALA-PDT in ALAD silenced cells. Pb2+ treatment in MEL cells impaired ALAD activity and reduced PpIX synthesis but to a lesser extent. In conclusion, we show that a dramatic reduction in PpIX accumulation following down regulation of ALAD expression prevents an efficient PDT. Thus, ALAD has a major role in regulating PpIX synthesis and ALA-PDT therapeutic outcome. Monitoring ALAD expression or activity in various tumors may be useful as prognostic tool to predict PDT efficacy.

International Society for the Social Studies Annual Conference Proceedings (Orlando, Florida, February 26-27, 2009). Volume 2009, Issue 1

ERIC Educational Resources Information Center

Russell, William Benedict, III, Ed.

2009-01-01

The "International Society for the Social Studies Annual Conference Proceedings" is a peer-reviewed professional publication published once a year following the annual conference. It contains the following papers: (1) Teacher Perceptions of Authentic Pedagogy: A Case Study of Professional Development in an African American High School's…

Proceedings of the Annual Review Conference (13th) on Atmospheric Transmission Models Held in Hanscom AFB, Massachusetts on 5-6 June 1990

DTIC Science & Technology

1990-06-01

PL-TR-92-2054 AD-A247 625 PROCEEDINGS OF THE 13TH ANNUAL REVIEW CONFERENCE ON ATMOSPHERIC TRANSMISSION MODELS, 5-6 JUNE 1990 Editors: F. X. Kneizys L...Security Classification) Proceedings of the 13th Annual Review Conference on Atmospheric Transmission Models. 12. PERSONAL AUTHOR(S) Editors, F.X...the 31 papers presented at the Thirteenth Annual Review Conference on Atmospheric Transmission Models held at the Geophysics Laborator-, (ASFC

Engaging the Learner. Annual Instructional Technology Conference (12th, Murfreesboro, Tennessee, April 1-3, 2007)

ERIC Educational Resources Information Center

Smith, Carter F.; Schneider, Gary F.; Kontos, George; Kuzat, Hanan; Janossy, James; Thurmond, Karen; Moore, Beth; Whitledge, Lynn; Speer, Priscilla; Harber, Annette; Bailey, Kathrine; Penney, Samantha

2007-01-01

The following is a collection of papers presented at the 12th annual Instructional Technology Conference at Middle Tennessee State University in Murfreesboro, Tennessee. This conference is an opportunity for higher-education professionals from across the country to discuss opportunities and challenges presented by instructional technology. The…

Annual National Small Business Conference (5th) Held in San Diego, California on May 19-21, 2008

DTIC Science & Technology

2008-05-21

Untitled Document 5th Annual National Small Business Conference.html[5/18/2016 3:28:09 PM] 5th Annual National Small Business Conference "Success...NDIA SESSION 1: WHERE SMALL BUSINESSES FAIL “What leads to small businesses failing after initial success?,” Mr. Bill Scheessele, President, MBDi...CHANGE IN YOUR FUTURE? Mergers, Acquisitions, and Small Businesses Mr. John Allen, Co-Head Defense and Government Services Group, BB&T Capital

The GLO1 C332 (Ala111) allele confers autism vulnerability: family-based genetic association and functional correlates.

PubMed

Gabriele, Stefano; Lombardi, Federica; Sacco, Roberto; Napolioni, Valerio; Altieri, Laura; Tirindelli, Maria Cristina; Gregorj, Chiara; Bravaccio, Carmela; Rousseau, Francis; Persico, Antonio M

2014-12-01

Glyoxalase I (GLO1) is a homodimeric Zn(2+)-dependent isomerase involved in the detoxification of methylglyoxal and in limiting the formation of advanced glycation end-products (AGE). We previously found the rs4746 A332 (Glu111) allele of the GLO1 gene, which encodes for glyoxalase I, associated with "unaffected sibling" status in families with one or more children affected by Autism Spectrum Disorder (ASD). To identify and characterize this protective allele, we sequenced GLO1 exons and exon-intron junctions, detecting two additional SNPs (rs1049346, rs1130534) in linkage disequilibrium with rs4746. A family-based association study involving 385 simplex and 20 multiplex Italian families yielded a significant association with autism driven only by the rs4746 C332 (Ala111) allele itself (P < 0.05 and P < 0.001 under additive and dominant/recessive models, respectively). Glyoxalase enzymatic activity was significantly reduced both in leukocytes and in post-mortem temporocortical tissue (N = 38 and 13, respectively) of typically developing C332 allele carriers (P < 0.05 and <0.01), with no difference in Glo1 protein levels. Conversely, AGE amounts were significantly higher in the same C332 post-mortem brains (P = 0.001), with a strong negative correlation between glyoxalase activity and AGE levels (τ = -0.588, P < 0.01). Instead, 19 autistic brains show a dysregulation of the glyoxalase-AGE axis (τ = -0.209, P = 0.260), with significant blunting of glyoxalase activity and AGE amounts compared to controls (P < 0.05), and loss of rs4746 genotype effects. In summary, the GLO1 C332 (Ala111) allele confers autism vulnerability by reducing brain glyoxalase activity and enhancing AGE formation, but years after an autism diagnosis the glyoxalase-AGE axis appears profoundly disrupted, with loss of C332 allelic effects. Copyright © 2014 Elsevier Ltd. All rights reserved.

The 50th Annual Maize Genetics Conference

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cone, Karen

The 50th Annual Maize Genetics Conference was held February 27 - March 2, 2008 at the Marriott Wardman Park Hotel in Washington, D.C. As the golden anniversary of the Conference and coinciding with the release of a draft of the maize genome sequence, this was a special meeting. To publicize this unique occasion, meeting organizers hosted a press conference, which was attended by members of the press representing science and non-science publications, and an evening reception at the Smithsonian National Museum of Natural History, where the draft sequence was announced and awards were presented to Dr. Mary Clutter and Senatormore » Kit Bond to thank them for their outstanding contributions to maize genetics and genomics research. As usual, the Conference provided an invigorating forum for exchange of recent research results in many areas of maize genetics, e.g., cytogenetics, development, molecular genetics, transposable element biology, biochemical genetics, and genomics. Results were shared via both oral and poster presentations. Invited talks were given by four distinguished geneticists: Vicki Chandler, University of Arizona; John Doebley, University of Wisconsin; Susan Wessler, University of Georgia; and Richard Wilson, Washington University. There were 46 short talks and 241 poster presentations. The Conference was attended by over 500 participants. This included a large number of first-time participants in the meeting and an increasingly visible presence by individuals from underrepresented groups. Although we do not have concrete counts, there seem to be more African American, African and Hispanic/Latino attendees coming to the meeting than in years past. In addition, this meeting attracted many participants from outside the U.S. Student participation continues to be hallmark of the spirit of free exchange and cooperation characteristic of the maize genetics community. With the generous support provided by DOE, USDA NSF, and corporate/private donors

IBC's 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics international conferences and the 2012 Annual Meeting of The Antibody Society: December 3-6, 2012, San Diego, CA.

PubMed

Klöhn, Peter-Christian; Wuellner, Ulrich; Zizlsperger, Nora; Zhou, Yu; Tavares, Daniel; Berger, Sven; Zettlitz, Kirstin A; Proetzel, Gabriele; Yong, May; Begent, Richard H J; Reichert, Janice M

2013-01-01

The 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics international conferences, and the 2012 Annual Meeting of The Antibody Society, organized by IBC Life Sciences with contributions from The Antibody Society and two Scientific Advisory Boards, were held December 3-6, 2012 in San Diego, CA. The meeting drew over 800 participants who attended sessions on a wide variety of topics relevant to antibody research and development. As a prelude to the main events, a pre-conference workshop held on December 2, 2012 focused on intellectual property issues that impact antibody engineering. The Antibody Engineering Conference was composed of six sessions held December 3-5, 2012: (1) From Receptor Biology to Therapy; (2) Antibodies in a Complex Environment; (3) Antibody Targeted CNS Therapy: Beyond the Blood Brain Barrier; (4) Deep Sequencing in B Cell Biology and Antibody Libraries; (5) Systems Medicine in the Development of Antibody Therapies/Systematic Validation of Novel Antibody Targets; and (6) Antibody Activity and Animal Models. The Antibody Therapeutics conference comprised four sessions held December 4-5, 2012: (1) Clinical and Preclinical Updates of Antibody-Drug Conjugates; (2) Multifunctional Antibodies and Antibody Combinations: Clinical Focus; (3) Development Status of Immunomodulatory Therapeutic Antibodies; and (4) Modulating the Half-Life of Antibody Therapeutics. The Antibody Society's special session on applications for recording and sharing data based on GIATE was held on December 5, 2012, and the conferences concluded with two combined sessions on December 5-6, 2012: (1) Development Status of Early Stage Therapeutic Antibodies; and (2) Immunomodulatory Antibodies for Cancer Therapy.

Annual State of Michigan Personnel Officers Conference. (23rd, Cadillac, Michigan, September 15-17, 1969).

ERIC Educational Resources Information Center

Michigan State Dept. of Civil Service, Lansing.

The 23rd Annual State of Michigan Personnel Officers' Conference examined the workings of employee relations with employee organizations. The highlights are reported in this manual. A panel of speakers from industry and education provided conference participants with different points of view and a broadened outlook in the difficult areas of…

The First Annual Health Promotion in Day Care Conference (Washington, D.C., April 7, 1984). Conference Proceedings Report.

ERIC Educational Resources Information Center

Hammonds, Karl E.; Brathwaite, Rudolph L.

Conducted to disseminate information about health care issues in the day care environment, the First Annual Health Promotion in Day Care Conference was attended by approximately 200 health care providers, parents, and advocates in the metropolitan Washington, D.C. area. Health needs of the total child were addressed, and practical recommendations…

The International Society for the Social Studies Annual Conference Proceedings (Orlando, Florida, February 27-28, 2014). Volume 2014, Issue 1

ERIC Educational Resources Information Center

Russell, William Benedict, III, Ed.

2014-01-01

The "International Society for the Social Studies (ISSS) Annual Conference Proceedings" is a peer-reviewed professional publication published once a year following the annual conference. The following papers are included in the 2014 proceedings: (1) Legal Profession in the Technological Era with Special Reference to Women Lawyers in…

Selected papers from the Fourth Annual q-bio Conference on Cellular Information Processing.

PubMed

Nemenman, Ilya; Faeder, James R; Hlavacek, William S; Jiang, Yi; Wall, Michael E; Zilman, Anton

2011-10-01

This special issue consists of 11 original papers that elaborate on work presented at the Fourth Annual q-bio Conference on Cellular Information Processing, which was held on the campus of St John's College in Santa Fe, New Mexico, USA, 11-14 August 2010. Now in its fourth year, the q-bio conference has changed considerably over time. It is now well established and a major event in systems biology. The 2010 conference saw attendees from all continents (except Antarctica!) sharing novel results and participating in lively discussions at both the oral and poster sessions. The conference was oversubscribed and grew to 27 contributed talks, 16 poster spotlights and 137 contributed posters. We deliberately decreased the number of invited speakers to 21 to leave more space for contributed presentations, and the attendee feedback confirmed that the choice was a success. Although the q-bio conference has grown and matured, it has remained true to the original goal of being an intimate and dynamic event that brings together modeling, theory and quantitative experimentation for the study of cell regulation and information processing. Funded in part by a grant from NIGMS and by DOE funds through the Los Alamos National Laboratory Directed Research and Development program, the conference has continued to exhibit youth and vigor by attracting (and partially supporting) over 100 undergraduate, graduate and postdoctoral researchers. The associated q-bio summer school, which precedes the conference each year, further emphasizes the development of junior scientists and makes q-bio a singular event in its impact on the future of quantitative biology. In addition to an increased international presence, the conference has notably diversified its demographic representation within the USA, including increased participation from the southeastern corner of the country. One big change in the conference this year is our new publication partner, Physical Biology. Although we are very

Thirteenth annual U.S. DOE low-level radioactive waste management conference: Proceedings

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1991-12-31

The 40 papers in this document comprise the proceedings of the Department of Energy`s Thirteenth Annual Low-Level Radioactive Waste Management Conference that was held in Atlanta, Georgia, on November 19--21, 1991. General subjects addressed during the conference included: disposal facility design; greater-than-class C low-level waste; public acceptance considerations; waste certification; site characterization; performance assessment; licensing and documentation; emerging low-level waste technologies; waste minimization; mixed waste; tracking and transportation; storage; and regulatory changes. Papers have been processed separately for inclusion on the data base.

The International Society for the Social Studies Annual Conference Proceedings (Orlando, Florida, February 26-27, 2015) Volume 2015, Issue 1

ERIC Educational Resources Information Center

Russell, William Benedict, III, Ed.

2015-01-01

The "International Society for the Social Studies (ISSS) Annual Conference Proceedings" is a peer-reviewed professional publication published once a year following the annual conference. The following papers are included in the 2015 proceedings: (1) Local History and Local Culture at the Core of Elementary Social Studies Curriculum (C.…

Proceedings of the Adult Higher Education Alliance Annual Conference (35th, Orlando, Florida, March 10-11, 2015)

ERIC Educational Resources Information Center

Elufiede, Oluwakemi, Ed.; Flynn, Bonnie, Ed.

2015-01-01

This document contains the proceedings of The Adult Higher Education Alliance 35th Annual Conference. The theme of the conference was Adult and Higher Education in the Contemporary World: Its Role In Cultural Literacy. The conference was held on March 10-11, 2015. The event was hosted by and held at the College of Education and Human Performance,…

Center for Transportation Studies 24th annual transportation research conference, May 22-23, 2013, Saint Paul, Minnesota.

DOT National Transportation Integrated Search

2013-05-01

The University of Minnesotas Center for Transportation : Studies is pleased to present its 24th Annual Transportation : Research Conference, May 22-23, 2013. The conference will : be held at the Saint Paul RiverCentre, 175 West Kellogg : Boulevard...

ALA-Butyrate prodrugs for Photo-Dynamic Therapy

NASA Astrophysics Data System (ADS)

Berkovitch, G.; Nudelman, A.; Ehenberg, B.; Rephaeli, A.; Malik, Z.

2010-05-01

The use of 5-aminolevulinic acid (ALA) administration has led to many applications of photodynamic therapy (PDT) in cancer. However, the hydrophilic nature of ALA limits its ability to penetrate the cells and tissues, and therefore the need for ALA derivatives became an urgent research target. In this study we investigated the activity of novel multifunctional acyloxyalkyl ester prodrugs of ALA that upon metabolic hydrolysis release active components such as, formaldehyde, and the histone deacetylase inhibitory moiety, butyric acid. Evaluation of these prodrugs under photo-irradiation conditions showed that butyryloxyethyl 5-amino-4-oxopentanoate (ALA-BAC) generated the most efficient photodynamic destruction compared to ALA. ALA-BAC stimulated a rapid biosynthesis of protoporphyrin IX (PpIX) in human glioblastoma U-251 cells which resulted in generation of intracellular ROS, reduction of mitochondrial activity, leading to apoptotic and necrotic death of the cells. The apoptotic cell death induced by ALA / ALA-BAC followed by PDT equally activate intrinsic and extrinsic apoptotic signals and both pathways may occur simultaneously. The main advantage of ALA-BAC over ALA stems from its ability to induce photo-damage at a significantly lower dose than ALA.

Proceedings of the Annual Federal Forecasters Conference (2nd, Washington, D.C., September 6-7, 1989).

ERIC Educational Resources Information Center

Sonnenberg, William; And Others

The Second Annual Federal Forecasters Conference, "Forecasting and Public Policy", provided a forum where forecasters from various Federal agencies could meet and discuss aspects of forecasting in the U.S. Government. A total of 140 forecasters from 42 Federal agencies and other organizations attended the conference. Opening remarks by…

7th Annual NASA/Contractors Conference on Quality and Productivity: "Total Quality Leadership"

NASA Technical Reports Server (NTRS)

1991-01-01

More than 750 NASA, government, contractor, and academic representatives attended the Seventh Annual NASA/Contractors Conference on Quality and Productivity on October 12-13, 1990, in Grenelefe, Florida. The panel presentations and keynote speeches revolving around the theme of 'Total Quality Leadership' provided a solid base of understanding of the importance, benefits, and principles of total quality management. The implementation of these strategies is critical if we are to effectively pursue our mission of continuous quality improvement and reliability in our products, processess, and services. The annual NASA/contractors conferences serve as catalysts for achieving success in this mission. The conference was highlighted by the announcement of the first recipients of the George M. Low Trophy: NASA's Quality and Excellence Award. My congratulations go out to all nine finalist organizations and to the two recipients of this prestigious honor: Rockwell Space Systems Division and Marotta Scientific Controls, Inc. (the first small business to achieve this honor). These organizations have demonstrated a commitment to quality that is unsurpassed in the aerospace industry. This report summarizes the presentations and is not intended to be a verbatim proceedings document. You are encouraged to contact the speakers with any requests for further information.

Summary Report of the Seventh Annual NASA/Contractors Conference on Quality and Productivity: "Total Quality Leadership"

NASA Technical Reports Server (NTRS)

1991-01-01

More than 750 NASA, government, contractor, and academic representatives attended the Seventh Annual NASA/Contractors Conference on Quality and Productivity on October 12-13, 1990, in Grenelefe, Florida. The panel presentations and keynote speeches revolving around the theme of 'Total Quality Leadership" provided a solid base of understanding of the importance, benefits, and principles of total quality management. The implementation of these strategies is critical if we are to effectively pursue our mission of continuous quality improvement and reliability in our products, processes, and services. The annual NASA/contractors conferences serve as catalysts for achieving success in this mission.

The International Society for the Social Studies Annual Conference Proceedings (Orlando, Florida, February 28 & March 1, 2013). Volume 2013, Issue 1

ERIC Educational Resources Information Center

Russell, William Benedict, III, Ed.

2013-01-01

The "ISSS Annual Conference Proceedings" is a peer-reviewed professional publication published once a year following the annual conference. The following papers are included in the 2013 proceedings: (1) Teaching About Asia in a Social Science Education Program (Cyndi Mottola Poole and Joshua L. Kenna); (2) Teaching Students about…

Boys to Men: Conference Report. Media Messages about Masculinity: Annual Children & the Media Conference (Los Angeles, California, September 1999).

ERIC Educational Resources Information Center

Lapp, Joan

The Sixth Annual Children and the Media Conference, hosted by Children Now, focused on the media's role and potential influence on boys. This report highlights the thinking of participating advocates, academics, entertainment industry leaders, and children. Following excerpts from a keynote address by William Pollack of Harvard Medical School, the…

6th Annual Earth System Grid Federation Face to Face Conference Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, D. N.

The Sixth Annual Face-to-Face (F2F) Conference of the Earth System Grid Federation (ESGF), a global consortium of international government agencies, institutions, and companies dedicated to the creation, management, analysis, and distribution of extreme-scale scientific data, was held December 5–9, 2016, in Washington, D.C.

Proceedings of the annual solar thermal technology research and development conference

DOE Office of Scientific and Technical Information (OSTI.GOV)

Couch, W.A.

1989-02-01

The Annual Solar Thermal Technology Research and Development Conference is being held at the Holiday Inn Crowne Plaza in Arlington, Virgina, Marh 8 and 9, 1989. This year the conference is meeting in conjunction with SOLTECH '89. SOLTECH '89 is a jointly sponsored meeting of the Solar Energy Industries Association, Interstate Solar Coordination Council, Sandia National Laboratories and the Solar Energy Research Institute. This report contains the agenda, extended abstracts and most significant visual aids used by the speakers during the Solar Thermal Technology research and development sessions. The program is divided into three sessions: Solar Electric Technology, Non-Electric Researchmore » and Development and Applications, and Concentrators.« less

ALA Conference 2009: The Second City's Newest Restaurants

ERIC Educational Resources Information Center

Daugherty, Robert Allen

2009-01-01

In this article, the author lists some of his favorites among Chicago's new restaurants. Most of the restaurants listed are easily accessible from the conference hotels by foot, taxi, or public transportation. The Chicago Transit Authority's (CTA) helpful trip planner can be used to determine the quickest and easiest routes. The price guide is…

Celebrating Partnerships. Highlights of the Annual Community Education Conference (6th, River Grove, IL, November 14, 1997).

ERIC Educational Resources Information Center

Solorzano, Sylvia M., Ed.

This paper is published annually by the Celebrating Partnerships Conference Planning Committee to share information on successful partnership programs that address community issues and concerns. The papers were presented at a conference in honor of National Community Education Day. This collection illustrates the efforts of diverse community…

Proceedings of the Fifteenth Annual Conference on Fossil Energy Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Judkins, R.R.

2002-02-12

The Fifteenth Annual Conference on Fossil Energy Materials was held in Knoxville, Tennessee, on April 30 through May 2, 2001. The meeting was sponsored by the U.S. Department of Energy's (DOE) Office of Fossil Energy through the Advanced Research Materials Program (ARM). The objective of the ARM Program is to conduct research and development on materials for longer-term fossil energy applications, as well as for generic needs of various fossil fuel technologies. The management of the program has been decentralized to the DOE Oak Ridge Operations Office and Oak Ridge National Laboratory (ORNL). The research is performed by staff membersmore » at ORNL and by researchers at other national laboratories, universities, and in private industry. The work is divided into the following categories: (1) structural, ceramics, (2) new alloys and coatings, (3) functional materials, and (4) technology development and transfer. These proceedings were produced primarily from electronic files provided by the authors. They have been neither refereed nor extensively edited. However, most of the papers have already undergone technical review within the individual organizations before submission to the Program Office. The proceedings are available on the Fossil Energy home page at http://www.ornl.gov/fossil (Workshops and Conferences). The successful completion of the conference and publication of the proceedings has required help from several people. The organizers wish to thank Angela Beach of the ORNL Conference Office for her help in the many arrangements, and the numerous staff and support personnel associated with the conference. Finally, we express our sincere appreciation to the authors whose efforts are the very basis of the conference.« less

78 FR 44574 - Third Annual Food and Drug Administration Health Professional Organizations Conference

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-24

... . Contact: Brenda Rose, Office of Special Health Issues, 10903 New Hampshire Ave., Silver Spring, MD 20993... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration [Docket No. FDA-2013-N-0001] Third Annual Food and Drug Administration Health Professional Organizations Conference AGENCY: Food and...

"Be Informed, Stay Connected, Community Transformation!" Selected Papers from the PIALA Conference 2014, Pacific Islands Association of Libraries, Archives, and Museums Annual Conference (24th, Koror, Republic of Palau, Nov 10-15, 2014)

ERIC Educational Resources Information Center

Drake, Paul Burton

2015-01-01

This publication follows the tradition of publishing selected papers from the Pacific Islands Association of Libraries, Archives and Museums (PIALA) annual conferences. This 24th annual conference was held in Koror, Republic of Palau, November 10-15, 2014. This volume includes a listing of the PIALA 2014 Organizing Committee and PIALA Officers and…

Reports from the 2011 Missouri Library Association Annual Conference, October 5-7, 2011

ERIC Educational Resources Information Center

Miller, Andrea

2012-01-01

This article presents reports from the 2011 Missouri Library Association Annual Conference held on October 5-7, 2011. The first report, entitled "Online Information Literacy Instruction: Challenges and Strategies," was presented by Kristine Stewart and Kyle Denlinger, University of Missouri-Columbia. Stewart and Denlinger talk about…

Listen to Me: Report of the Ninth Annual NEA-CHR Conference, "Implementing Cultural Diversity in Instructional Programs".

ERIC Educational Resources Information Center

National Education Association, Washington, DC. Center for Human Relations.

This publication is a compilation of speeches, seminar summaries, and participant reactions and recommendations from the Ninth Annual NEA-CHR Conference printed in both English and Spanish. The conference was designed to present the concept of cultural pluralism and to suggest ways of implementing this concept in instructional programs. The…

Eleventh Annual Conference Proceedings: The Freedom to be Accountable: Adult Student Personnel Association.

ERIC Educational Resources Information Center

Miller, Ronald H., Ed.; Becker, Dorothy R., Ed.

The conference proceedings focus on the concepts of academic freedom and public accountability in the educational process. It includes the complete texts of papers and addresses presented; proceedings of the Adult Student Personnel Annual business meeting; summary reports from the panels on special degree programs for adults and counseling for…

RESET: Information Services Trends in 2012. Selected Papers from PIALA Conference 2012, Pacific Islands Association of Libraries, Archives, and Museums Annual Conference (22nd, Tumon, U.S. Territory of Guam, Nov 13-16, 2012)

ERIC Educational Resources Information Center

Drake, Paul B., Ed.

2013-01-01

This publication follows the tradition of publishing selected papers from Pacific Islands Association of Libraries, Archives and Museums (PIALA) annual conferences. This 22th annual conference was held in Tumon, Territory of Guam USA, November 13-16, 2012. The volume begins with a listing of the members of the PIALA 2012 Planning Committee and…

Report of the Annual Vocational, Technical and Adult Educators' Conference (1st, Jacksonville, Florida, August 4-9, 1968).

ERIC Educational Resources Information Center

Florida State Dept. of Education, Tallahassee. Div. of Vocational, Technical and Adult Education.

This first annual conference had as its theme "People, Education, Business and Industry--Partners for Excellence." Major speeches for the general conference program included: (1) "Selling the American System to Americans," by K. McFarland, (2) "Projection for the 70's," by C.W. Proehl, (3) "How to Help…

ALA Pretreatment Improves Waterlogging Tolerance of Fig Plants

PubMed Central

An, Yuyan; Qi, Lin; Wang, Liangju

2016-01-01

5-aminolevulinic acid (ALA), a natural and environmentally friendly plant growth regulator, can improve plant tolerance to various environmental stresses. However, whether ALA can improve plant waterlogging tolerance is unknown. Here, we investigated the effects of ALA pretreatment on the waterlogging-induced damage of fig (Ficus carica Linn.) plants, which often suffer from waterlogging stress. ALA pretreatment significantly alleviated stress-induced morphological damage, increased leaf relative water content (RWC), and reduced leaf superoxide anion (O2⋅¯) production rate and malonaldehyde (MDA) content in fig leaves, indicating ALA mitigates waterlogging stress of fig plants. We further demonstrated that ALA pretreatment largely promoted leaf chlorophyll content, photosynthetic electron transfer ability, and photosynthetic performance index, indicating ALA significantly improves plant photosynthetic efficiency under waterlogging stress. Moreover, ALA pretreatment significantly increased activities of leaf superoxide dismutase (SOD) and peroxidase (POD), root vigor, and activities of root alcohol dehydrogenase (ADH), and lactate dehydrogenase (LDH), indicating ALA also significantly improves antioxidant ability and root function of fig plants under waterlogging stress. Taken together, ALA pretreatment improves waterlogging tolerance of fig plants significantly, and the promoted root respiration, leaf photosynthesis, and antioxidant ability may contribute greatly to this improvement. Our data firstly shows that ALA can improve plant waterlogging tolerance. PMID:26789407

Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference (25th, Tarrytown, New York, March 25-26, 2011)

ERIC Educational Resources Information Center

Howell-Carter, Marya, Ed.; Gonder, Jennifer, Ed.

2011-01-01

Conference proceedings of the 25th Annual Conference on the Teaching of Psychology: Ideas and Innovations, sponsored by the Psychology Department of the State University of New York at Farmingdale. The conference theme for 2011 was: The Future of the Undergraduate Psychology Major: New Directions in an Evolving Educational Climate. The Conference…

Pacific Telecommunications Council Annual Conference Proceedings (19th, Honolulu, Hawaii, January 19-22, 1997).

ERIC Educational Resources Information Center

Wedemeyer, Dan J., Ed.; Nickelson, Richard, Ed.

This PTC'97 volume contains papers presented at the 19th annual conference of the Pacific Telecommunications Council, "Pacific Connections: Policy and Technology in the Information Economy" (1997). Three super-session groupings--industry, policy, and technology--provide attendees with a conceptual foundation from which subsequent…

We Navigate Together into the Future. Selected Papers from the PIALA Conference 2016, Pacific Islands Association of Libraries, Archives, and Museums Annual Conference (26th, Colonia, Yap State, Federated States of Micronesia, November 21-26, 2016)

ERIC Educational Resources Information Center

Drake, Paul Burton, Ed.

2017-01-01

This publication follows the tradition of publishing selected papers from the Pacific Islands Association of Libraries, Archives and Museums (PIALA) annual conferences. This 26th annual conference was held in Colonia, Yap State, Federated States of Micronesia, November 21-26, 2016 and celebrated the Association's Twenty-Fifth anniversary. This…

Annual Pennsylvania Conference on Postsecondary Occupational Education: Programming Postsecondary Occupational Education. (Ninth, Pennsylvania State University, September 28-29, 1977).

ERIC Educational Resources Information Center

Martorana, S. V., Ed.; And Others

This publication contains the text of the main presentations and the highlights of discussion groups from the Ninth Annual Pennsylvania Conference on Postsecondary Occupational Education. The conference theme was "Programming Postsecondary Occupational Education." Ewald Nyquist, the first speaker, delineated the problems faced by…

Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference (26th, Tarrytown, New York, March 23-24, 2012)

ERIC Educational Resources Information Center

Howell-Carter, Marya, Ed.; Gonder, Jennifer, Ed.; Mushtaq, Zahra, Ed.

2012-01-01

Included herein is the conference proceedings of the 26th Annual Conference on the Teaching of Psychology: Ideas and Innovations, sponsored by the Psychology Department of the State University of New York at Farmingdale. The conference theme for 2012 was: The value of an undergraduate degree in psychology: Why psychology--Why now?. The Conference…

Pacific Telecommunications Council Annual Conference Proceedings (18th, Honolulu, Hawaii, January 14-18, 1996).

ERIC Educational Resources Information Center

Wedemeyer, Dan J. Ed.; Nickelson, Richard, Ed.

The Pacific Telecommunications Council's 18th annual conference is presented in two volumes. The PTC'96 gathering focused on seven streams: socio-economic issues; regulatory, legal and political issues; business and finance solutions; country studies; education, training, and human resources; convergence and networks; and technologies and…

Biology Practicals That Work: SAPS Drop-In Sessions at the ASE Annual Conference 2017

ERIC Educational Resources Information Center

Jenkins, Dan; Goodger, Beverley

2017-01-01

This article reviews the practical plant biology workshops presented by Science and Plants for Schools (SAPS) at the Association for Science Education Annual Conference 2017. The well-received workshops enabled attendees to try out SAPS practical investigations, with the support of experienced "experts" and colleagues. The resources…

Computers in Libraries Annual Conference (16th, Washington, DC, March 14-16, 2001): Collected Presentations.

ERIC Educational Resources Information Center

Nixon, Carol, Comp.

This book contains the presentations of the 16th annual Computers in Libraries Conference. Contents include: "Creating New Services & Opportunities through Web Databases"; "Influencing Change and Student Learning through Staff Development"; "Top Ten Navigation Tips"; "Library of the Year: Gwinnett County…

Introducing medical students to careers in medical education: the student track at an annual medical education conference.

PubMed

Blatt, Benjamin; Plack, Margaret; Suzuki, Mari; Arepalli, Sruthi; Schroth, Scott; Stagnaro-Green, Alex

2013-08-01

Few avenues exist to familiarize medical students with careers as clinician-educators, and the clinician-educator career pathway has not been well defined. In this article, the authors describe how they integrated a career-oriented student track into the 2011 Northeast Group on Educational Affairs (NEGEA) annual retreat to introduce students to careers in medical education. Annual education conferences are principal sources of educational scholarship, networking, collaboration, and information sharing; as such, they represent attractive venues for early exposure to the culture of medical education. The authors' goal in creating the NEGEA conference student track was to excite students about careers in medical education by providing them with an array of opportunities for active involvement in both student-specific and general conference activities.The authors draw from their experience to provide a guide for recruiting student participants to career-building student tracks. They also offer a guide for developing future student tracks, based on their experience and grounded in social cognitive career theory. Although their focus is on medical education, they believe these guides will be useful for educators planning a conference-based student track in any field.

Expression of the alaE gene is positively regulated by the global regulator Lrp in response to intracellular accumulation of l-alanine in Escherichia coli.

PubMed

Ihara, Kohei; Sato, Kazuki; Hori, Hatsuhiro; Makino, Yumiko; Shigenobu, Shuji; Ando, Tasuke; Isogai, Emiko; Yoneyama, Hiroshi

2017-04-01

The alaE gene in Escherichia coli encodes an l-alanine exporter that catalyzes the active export of l-alanine using proton electrochemical potential. In our previous study, alaE expression was shown to increase in the presence of l-alanyl-l-alanine (Ala-Ala). In this study, the global regulator leucine-responsive regulatory protein (Lrp) was identified as an activator of the alaE gene. A promoter less β-galactosidase gene was fused to an alaE upstream region (240 nucleotides). Cells that were lacZ-deficient and harbored this reporter plasmid showed significant induction of β-galactosidase activity (approximately 17-fold) in the presence of 6 mM l-alanine, l-leucine, and Ala-Ala. However, a reporter plasmid possessing a smaller alaE upstream region (180 nucleotides) yielded transformants with strikingly low enzyme activity under the same conditions. In contrast, lrp-deficient cells showed almost no β-galactosidase induction, indicating that Lrp positively regulates alaE expression. We next performed an electrophoretic mobility shift assay (EMSA) and a DNase I footprinting assay using purified hexahistidine-tagged Lrp (Lrp-His). Consequently, we found that Lrp-His binds to the alaE upstream region spanning nucleotide -161 to -83 with a physiologically relevant affinity (apparent K D , 288.7 ± 83.8 nM). Furthermore, the binding affinity of Lrp-His toward its cis-element was increased by l-alanine and l-leucine, but not by Ala-Ala and d-alanine. Based on these results, we concluded that the gene expression of the alaE is regulated by Lrp in response to intracellular levels of l-alanine, which eventually leads to intracellular homeostasis of l-alanine concentrations. Copyright © 2016 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

The Eighth Annual Air Pollution Medical Research Conference, Los Angeles, March 2-4, 1966.

ERIC Educational Resources Information Center

Archives of Environmental Health, 1967

1967-01-01

Papers read before the Eighth Annual American Medical Association Air Pollution Medical Research Conference, Los Angeles, California, March 2-4, 1966, are presented in this document. Topics deal with basic approaches to the study of the effects of inhaled irritants on the lung; environmental parameters in relation to host responses; biological…

Emerging frontiers in healthcare research and delivery.: the 16th Annual HMO Research Network Conference, March 21-24, 2010, Austin, Texas.

PubMed

Stevens, Alan B; Sanghi, Sandhya

2010-12-01

The Health Maintenance Organization Research Network (HMORN), a consortium of 16 healthcare delivery systems with integrated research centers, held their 16(th) annual conference in Austin, Texas from March 21-24, 2010. The conference was hosted by Scott & White Healthcare. Its theme "Emerging Frontiers in Healthcare Research and Delivery" reflected the objective of the conference which was to build synergy among scientists and clinicians to influence the health of the nation; to demonstrate the network's commitment to reach beyond traditional collaborators; discuss tools and technologies; and to expand opportunities for public-private partnerships in cutting-edge healthcare research and delivery. More than 320 researchers and healthcare professionals, representing each of the member HMOs, participated in this conference. Representatives from the AHRQ, CDC, NCI and NIH met with researchers to advance the quality and breadth of public domain research in HMOs. The objective of this article is to provide information about the HMORN and its 16(th) annual conference.

Plenary Presentations. Pacific Telecommunications Council Annual Conference (16th, Honolulu, Hawaii, January 16-20, 1994).

ERIC Educational Resources Information Center

Savage, James G., Ed.; Wedemeyer, Dan J., Ed.

This document contains the following plenary speeches from the 1994 annual conference of the Pacific Telecommunications Council (PTC): "Forging New Links--Focus on Developing Economies" by Sir Donald Maitland of the Independent Commission for World-Wide Telecommunications Development (United Kingdom); "The Missing Link: Still…

Proceedings of the sixth annual conference on fossil energy materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, N.C.; Judkins, R.R.

1992-07-01

The Sixth Annual Conference on Fossil Energy Materials was held in Oak Ridge, Tennessee, on May 12--14, 1992. The meeting was sponsored by the US Department of Energy's Office of Fossil Energy through the Advanced Research and Technology Development (AR TD) Materials Program, and ASM International. The objective of the AR TD Materials Program is to conduct research and development on materials for longer-term fossil energy applications as well as for generic needs of various fossil fuel technologies. The management of the Program has been decentralized to the DOE Field Office, Oak Ridge with Oak Ridge National Laboratory (ORNL) asmore » the technical support contractor. The research is performed by staff members at ORNL and by a substantial number of researchers at other national laboratories, universities, and in private industry. The work is divided into the following categories: (1) ceramics, (2) development and corrosion resistance of iron aluminide, advanced austenitic and chromium-niobium alloys, and (3) technology assessment and technology transfer. This conference is held each year to review the work on all of the projects of the Program. The agenda for the meeting is given in Appendix A, and a list of attendees is presented in Appendix B. ASM International cosponsored the conference, for which we are especially grateful.« less

Loss of the Arabidopsis thaliana P4-ATPases ALA6 and ALA7 impairs pollen fitness and alters the pollen tube plasma membrane.

PubMed

McDowell, Stephen C; López-Marqués, Rosa L; Cohen, Taylor; Brown, Elizabeth; Rosenberg, Alexa; Palmgren, Michael G; Harper, Jeffrey F

2015-01-01

Members of the P4 subfamily of P-type ATPases are thought to create and maintain lipid asymmetry in biological membranes by flipping specific lipids between membrane leaflets. In Arabidopsis, 7 of the 12 Aminophospholipid ATPase (ALA) family members are expressed in pollen. Here we show that double knockout of ALA6 and ALA7 (ala6/7) results in siliques with a ~2-fold reduction in seed set with a high frequency of empty seed positions near the bottom. Seed set was reduced to near zero when plants were grown under a hot/cold temperature stress. Reciprocal crosses indicate that the ala6/7 reproductive deficiencies are due to a defect related to pollen transmission. In-vitro growth assays provide evidence that ala6/7 pollen tubes are short and slow, with ~2-fold reductions in both maximal growth rate and overall length relative to wild-type. Outcrosses show that when ala6/7 pollen are in competition with wild-type pollen, they have a near 0% success rate in fertilizing ovules near the bottom of the pistil, consistent with ala6/7 pollen having short and slow growth defects. The ala6/7 phenotypes were rescued by the expression of either an ALA6-YFP or GFP-ALA6 fusion protein, which showed localization to both the plasma membrane and highly-mobile endomembrane structures. A mass spectrometry analysis of mature pollen grains revealed significant differences between ala6/7 and wild-type, both in the relative abundance of lipid classes and in the average number of double bonds present in acyl side chains. A change in the properties of the ala6/7 plasma membrane was also indicated by a ~10-fold reduction of labeling by lipophilic FM-dyes relative to wild-type. Together, these results indicate that ALA6 and ALA7 provide redundant activities that function to directly or indirectly change the distribution and abundance of lipids in pollen, and support a model in which ALA6 and ALA7 are critical for pollen fitness under normal and temperature-stress conditions.

Loss of the Arabidopsis thaliana P4-ATPases ALA6 and ALA7 impairs pollen fitness and alters the pollen tube plasma membrane

PubMed Central

McDowell, Stephen C.; López-Marqués, Rosa L.; Cohen, Taylor; Brown, Elizabeth; Rosenberg, Alexa; Palmgren, Michael G.; Harper, Jeffrey F.

2015-01-01

Members of the P4 subfamily of P-type ATPases are thought to create and maintain lipid asymmetry in biological membranes by flipping specific lipids between membrane leaflets. In Arabidopsis, 7 of the 12 Aminophospholipid ATPase (ALA) family members are expressed in pollen. Here we show that double knockout of ALA6 and ALA7 (ala6/7) results in siliques with a ~2-fold reduction in seed set with a high frequency of empty seed positions near the bottom. Seed set was reduced to near zero when plants were grown under a hot/cold temperature stress. Reciprocal crosses indicate that the ala6/7 reproductive deficiencies are due to a defect related to pollen transmission. In-vitro growth assays provide evidence that ala6/7 pollen tubes are short and slow, with ~2-fold reductions in both maximal growth rate and overall length relative to wild-type. Outcrosses show that when ala6/7 pollen are in competition with wild-type pollen, they have a near 0% success rate in fertilizing ovules near the bottom of the pistil, consistent with ala6/7 pollen having short and slow growth defects. The ala6/7 phenotypes were rescued by the expression of either an ALA6-YFP or GFP-ALA6 fusion protein, which showed localization to both the plasma membrane and highly-mobile endomembrane structures. A mass spectrometry analysis of mature pollen grains revealed significant differences between ala6/7 and wild-type, both in the relative abundance of lipid classes and in the average number of double bonds present in acyl side chains. A change in the properties of the ala6/7 plasma membrane was also indicated by a ~10-fold reduction of labeling by lipophilic FM-dyes relative to wild-type. Together, these results indicate that ALA6 and ALA7 provide redundant activities that function to directly or indirectly change the distribution and abundance of lipids in pollen, and support a model in which ALA6 and ALA7 are critical for pollen fitness under normal and temperature-stress conditions. PMID:25954280

Computers in Libraries Annual Conference (17th, Washington, DC, March 13-15, 2002): Collected Presentations.

ERIC Educational Resources Information Center

Nixon, Carol, Comp.

This book contains presentations from the 17th annual Computers in Libraries Conference. Topics covered include: chatting with a librarian; verbots for library Web sites; collaborative IT (Information Technology) planning at Montgomery County Public Library (Maryland); designing a local government taxonomy; Weblogs; new roles for librarians in…

11th Annual Small Business Conference :Army and Small Business: Success Thru Partnership

DTIC Science & Technology

2007-11-08

Management Commands… Soldier Focused As of 12 Sep 07 Technology /System Improvements Army Sustainment Command: AMC’s Face to the Field Improvement Suggestions...Acquisition, Logistics and Technology ) “Update on the State of the Army Small Business Program”, Ms. Tracey L. Pinson, Director, Small and...Partner”, Ms. January Dennison, President, Technology Research Consultants, Inc.  11th Annual Small Business Conference Objective & Scope

Farmingdale State College Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference (27th, Tarrytown, New York, April 5-6, 2013)

ERIC Educational Resources Information Center

Gonder, Jennifer, Ed.; Howell-Carter, Marya, Ed.; Anderson, Jessica, Ed.

2013-01-01

Included herein is the conference proceedings of the 27th Annual Conference on the Teaching of Psychology: Ideas and Innovations, sponsored by the Psychology Department of the State University of New York at Farmingdale. The conference theme for 2013 was: The Science of Learning. The Conference featured a keynote address by Victor Benassi, Ph.D.…

Collective Bargaining and the Future of Higher Education. Proceedings of the Fifth Annual Conference.

ERIC Educational Resources Information Center

Levenstein, Aaron, Ed.; Lang, Theodore H.

Papers presented at the fifth annual Conference of the National Center for the Study of Collective Bargaining in Higher Education are provided. The union's and management's views of the impact of fiscal crisis on collective bargaining are given in the first two papers by Robert W. Miner and Caesar Naples. The next two presentations by Robert…

A Report on the 30th Annual Conference of the International Association of Scientific and Technological University Libraries (IATUL)

ERIC Educational Resources Information Center

Tripathi, Manorama

2010-01-01

Purpose: The paper aims to report on the 30th IATUL Annual Conference held in Leuven, Belgium, 1-4 June, 2009. Design/methodology/approach: The paper summarises the major themes of the conference as well as giving some specific details of developments at the Indira Gandhi National Open University in India, which supplement the author's…

ALA Meets at Ground-Zero, New York City Conference Report.

ERIC Educational Resources Information Center

Wilson Library Bulletin, 1986

1986-01-01

Description of 1986 American Library Association Conference summarizes significant organizational actions and presentations on upgrading automation systems, censorship, federal libraries, fees and public library services, black community information needs, Linked Systems Project, libraries and the homeless, new products exhibited, and 1994…

Next Generation Communications: Making IT Work. Pacific Telecommunications Council Annual Conference Proceedings (24th, Honolulu, Hawaii, January 13-17, 2002).

ERIC Educational Resources Information Center

Pacific Telecommunications Council, Honolulu, HI.

This proceedings includes the papers presented at the 2002 conference of the Pacific Telecommunications Council (PTC), with its theme "Next Generation Communications: Making IT Work." The PTC2002 annual conference seeks to focus on harnessing the complexities of the broadest range of communications technologies and services for the user.…

Goodbye, Orlando? Heat and Hot Issues, Theme Parks, and a Busy Show Floor

ERIC Educational Resources Information Center

Berry, John; Blumenstein, Lynn; DiMattia, Susan; Kenney, Brian; Oder, Norman; Rogers, Michael

2004-01-01

The American Library Association's (ALA) Annual Conference, June 24?30, in steamy Orlando, drew 19,575 people, including 5,739 exhibitors, the lowest total since Miami in 1994, not counting the SARS-shadowed conference in Toronto last year (see statistics, p. 15). Although this years conference was filled with exciting events, this abstract is…

Proceedings of the Annual Utah Paraeducator Conference (3rd, Ogden, Utah, November 7-8, 1997).

ERIC Educational Resources Information Center

Morgan, Jill; Ashbaker, Betty

This paper gives a brief outline of the Third Annual Paraeducator Conference. Papers include: "How to Stop Problematic Behaviors" (H. K. Reavis); "Using Incentives with Tough Kids" (W. R. Jenson); "How Do I Accurately and Successfully Dispute My Own Worst Thoughts?" (M. W. Egan); "IDEA '97: The Law has Changed:…

Proceedings of the Annual Conference of the Western Australian Science Education Association (19th, Perth, Western Australia, Australia, November 18, 1994).

ERIC Educational Resources Information Center

Rennie, Leonie J., Ed.

The Western Australian Science Education Association is an informal group which meets annually for a conference. This document contains the proceedings of the 1994 conference. Papers included were: (1) "Relationship Between Cognitive Style and Students' Proportional Reasoning Ability" (Ayo Akatugba); (2) "Alternative Modes of…

The 10th Annual Bioassays and Bioanalytical Method Development Conference.

PubMed

Ma, Mark; Tudan, Christopher; Koltchev, Dolly

2015-01-01

The 10th Annual Bioassays and Bioanalytical Method Development Conference was hosted in Boston, MA, USA on 20-22 October 2014. This meeting brought together scientists from the biopharmaceutical and life sciences industries, the regulatory agency and academia to share and discuss current trends in cell-based assays and bioanalysis, challenges and ideas for the future of the bioassays and bioanalytical method development. The experiences associated with new and innovative technologies were evaluated as well as their impact on the current bioassays methodologies and bioanalysis workflow, including quality, feasibility, outsourcing strategies and challenges, productivity and compliance. Several presentations were also provided by members of the US FDA, sharing both scientific and regulatory paradigms including a most recent update on the position of the FDA with specific aspects of the draft Bioanalytical Method Validation guidance following its review of the industry's responses. The meeting was jointly coincided with the 15th Annual Immunogenicity for Biotherapeutics meeting, allowing for attendees to also familiarize themselves with new and emerging approaches to overcome the effect of immunogenicity, in addition to investigative strategies.

The association between the Pro12Ala variant in the PPARγ2 gene and type 2 diabetes mellitus and obesity in a Chinese population.

PubMed

Wang, Xia; Liu, Jun; Ouyang, Yingying; Fang, Min; Gao, Hui; Liu, Liegang

2013-01-01

Conflicting results have been reported on the association of the Pro12Ala polymorphism of the PPARγ2 gene with the risk of type 2 diabetes or obesity. A total of 3146 subjects with 1145 cases of type 2 diabetes and 2001 healthy controls were included in the study. Genomic DNA was obtained from blood samples and the screening for the gene polymorphisms was done using an allelic discrimination assay-by-design TaqMan method. Overall, the Ala allele frequency was 5.6% in control subjects and 3.9% in diabetes subjects (P = 0.023). We found a statistically significant association of carriers of the Ala allele with greater homoeostasis model assessment of beta cell function index in all subjects (P = 0.046). After controlling for confounders, carriers of the Ala allele had a decreased risk of diabetes compared with noncarriers [odds ratio (OR) 0.64, 95% confidence interval (CI) 0.49-0.83; P = 0.001]. A beneficial effect of the Ala allele was also observed for obesity (OR 0.64, 95% CI 0.42-0.96; P = 0.030). Our results suggested that the presence of the Ala allele may contribute to improved insulin secretory capacity and may confer protection from type 2 diabetes and obesity in the Chinese population.

Proceedings: Fourteenth annual EPRI conference on fuel science

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-05-01

EPRI's Fourteenth Annual Contractors' Conference on Fuel Science was held on May 18--19, 1989 in Palo Alto, CA. The conference featured results of work on coal science, coal liquefaction, methanol production, and coal oil coprocessing and coal upgrading. The following topics were discussed: recent development in coal liquefaction at the Wilsonville Clean Coal Research Center; British coal's liquid solvent extraction (LSE) process; feedstock reactivity in coal/oil co-processing; utility applications for coal-oil coprocessed fuels; effect of coal rank and quality on two-stage liquefaction; organic sulfur compounds in coals; the perchloroethylene refining process of high-sulfur coals; extraction of sulfur coals; extraction ofmore » sulfur from coal; agglomeration of bituminous and subbituminous coals; solubilization of coals by cell-free extracts derived from polyporus versicolor; remediation technologies and services; preliminary results from proof-of-concept testing of heavy liquid cyclone cleaning technology; clean-up of soil contaminated with tarry/oily organics; midwest ore processing company's coal benefication technology: recent prep plant, scale and laboratory activities; combustion characterization of coal-oil agglomerate fuels; status report on the liquid phase methanol project; biomimetic catalysis; hydroxylation of C{sub 2} {minus} C{sub 3} and cycloc{sub 6} hydrocarbons with Fe cluster catalysts as models for methane monooxygenase enzyme; methanol production scenarios; and modeling studies of the BNL low temperature methanol catalyst. Individual projects are processed separately for the data bases.« less

Impact of charged amino acid substitution in the transmembrane domain of L-alanine exporter, AlaE, of Escherichia coli on the L-alanine export.

PubMed

Kim, Seryoung; Ihara, Kohei; Katsube, Satoshi; Ando, Tasuke; Isogai, Emiko; Yoneyama, Hiroshi

2017-01-01

The Escherichia coli alaE gene encodes the L-alanine exporter, AlaE, that catalyzes active export of L-alanine using proton electrochemical potential. The transporter comprises only 149 amino acid residues and four predicted transmembrane domains (TMs), which contain three charged amino acid residues. The AlaE-deficient L-alanine non-metabolizing cells (ΔalaE cells) appeared hypersusceptible to L-alanyl-L-alanine showing a minimum inhibitory concentration (MIC) of 2.5 µg/ml for the dipeptide due to a toxic accumulation of L-alanine. To elucidate the mechanism by which AlaE exports L-alanine, we replaced charged amino acid residues in the TMs, glutamic acid-30 (TM-I), arginine-45 (TM-II), and aspartic acid-84 (TM-III) with their respective charge-conserved amino acid or a net neutral cysteine. The ΔalaE cells producing R45K or R45C appeared hypersusceptible to the dipeptide, indicating that arginine-45 is essential for AlaE activity. MIC of the dipeptide in the ΔalaE cells expressing E30D and E30C was 156 µg/ml and >10,000 µg/ml, respectively, thereby suggesting that a negative charge at this position is not essential. The ΔalaE cells expressing D84E or D84C showed an MIC >10,000 and 78 µg/ml, respectively, implying that a negative charge is required at this position. These results were generally consistent with that of the L-alanine accumulation experiments in intact cells. We therefore concluded that charged amino acid residues (R45 and D84) in the AlaE transmembrane domain play a pivotal role in L-alanine export. Replacement of three cysteine residues at C22, C28 (both in TM-I), and C135 (C-terminal region) with alanine showed only a marginal effect on L-alanine export.

Tenth annual scientific conference of the Prader-Willi Syndrome Association (USA), July 19, 1995, Seattle, Washington

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holm, V.A.; Hudgins, L.; Cassidy, S.B.

Each year for the last 10 years, scientists conducting research on Prader-Willi syndrome have come together to exchange information during a scientific conference held in conjunction with the annual Prader-Willi Syndrome Association (USA) meeting. Presentations based on submitted abstracts encompass such varied fields as genetics, endocrinology, pediatrics, nutrition, psychology, psychiatry, and education. This year`s scientific conference was held in Seattle, Washington, on July 19, 1995, in conjunction with the 14th PWSA (USA) meeting held July 20-23. Seventeen reports were presented at the scientific meeting, the abstracts of which follow.

Pacific Nations Broadcasting I; Symposium Held at the Annual Broadcast Industry Conference (22nd, San Francisco, April 19-22, 1972).

ERIC Educational Resources Information Center

Draper, Benjamin, Ed.

This document contains the papers presented at the Twenty-Second Annual Broadcast Industry Conference held at California State University, San Francisco, in 1972. The aim of the conference was to develop a better means of communication among nations existing in a world that has grown smaller because of the development of the communications media.…

Selections from the ABC 2017 Annual Conference, Dublin, Ireland: Finding a Pedagogical Pot o' Gold

ERIC Educational Resources Information Center

Whalen, D. Joel

2018-01-01

This article, the first of a two-part series, offers readers 13 teaching innovations debuted at the 2017 Association for Business Communication's annual conference in Dublin, Ireland. Assignment topics presented here include communication strategy and message-packaging skills, deep communication insights, and career and personal development.…

Annual Consumer Education "Catch-Up" Conference. (3rd, Washington, D.C., March 2-3, 1978).

ERIC Educational Resources Information Center

Office of Consumer Affairs, Washington, DC.

As stated in the introductory summary to these proceedings, the goals of the third annual national conference for consumer education were (1) to provide an introduction to resources and materials for persons new to the field of consumer education, (2) to highlight successful programs, (3) to provide up-to-date information on consumer legislation…

Beneficial reuse `96: The fourth annual conference on the recycle and reuse of radioactive scrap metal

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-02-01

From October 22-24, 1996 the University of Tennessee`s Energy, Environment and Resources Center and the Oak Ridge National Laboratory`s Center for Risk Management cosponsored Beneficial Reuse `96: The Fourth Annual Conference on the Recycle and Reuse of Radioactive Materials. Along with the traditional focus on radioactive scrap metals, this year`s conference included a wide range of topics pertaining to naturally occurring radioactive materials (NORM), and contaminated concrete reuse applications. As with previous Beneficial Reuse conferences, the primary goal of this year`s conference was to bring together stakeholder representatives for presentations, panel sessions and workshops on significant waste minimization issues surroundingmore » the recycle and reuse of contaminated metals and other materials. A wide range of industry, government and public stakeholder groups participated in this year`s conference. An international presence from Canada, Germany and Korea helped to make Beneficial Reuse `96 a well-rounded affair. Selected papers have been processed separately for inclusion in the Energy Science and Technology Database.« less

Threshold Concepts: From Personal Practice to Communities of Practice. Proceedings of the National Academy's Sixth Annual Conference and the Fourth Biennial Threshold Concepts Conference [E-publication] (Dublin, Ireland, June 27-29, 2012)

ERIC Educational Resources Information Center

O'Mahony, Catherine, Ed.; Buchanan, Avril, Ed.; O'Rourke, Mary, Ed.; Higgs, Bettie, Ed.

2014-01-01

The 6th Annual Conference of the National Academy for the Integration of Research, Teaching and Learning (NAIRTL) and the 4th Biennial Threshold Concepts Conference was held at Trinity College Dublin, Ireland, on June 27-29, 2012. The NAIRTL is a collaborative initiative between University College Cork, Cork Institute of Technology, National…

TRACE Authored Papers from the First through Ninth Annual Conferences on Rehabilitation Engineering Technology (1977-1986).

ERIC Educational Resources Information Center

Brady, Mary; And Others

Brief papers authored by staff of the Trace Research and Development Center on Communication, Control, and Computer Access for Handicapped Individuals and presented at the first through ninth annual conferences on rehabilitation engineering technology are presented. Papers have the following titles and authors: "The Data Routing Module:…

Proceedings: Eighteenth Annual Conference on Research in Medical Education, Washington, D.C., November 6-7, 1979.

ERIC Educational Resources Information Center

Jones, Deborah L., Comp.

The Research in Medical Education (RIME) Program Planning Committee's selections for program materials for the eighteenth annual conference on Research in Medical Education are contained in this volume. The agenda consisted of poster sessions, presentation of papers, and presentation of symposia. Poster sessions examined such topics as student…

4th Annual Conference for African-American Researchers in the Mathematical Sciences (CAARMS4). Preliminary Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tapia, Richard

1998-06-01

In June, The Center for Research on Parallel Computation (CRPC), an NSF-funded Science and Technology Center, hosted the 4th Annual Conference for African-American Reserachers in the Mathematical Sciences (CAARMS4) at Rice University. The main goal of this conference was to highlight current work by African-American researchers and graduate students in mathematics. This conference strengthened the mathematical sciences by encouraging the increased participation of African-American and underrepresented groups into the field, facilitating working relationships between them and helping to cultivate their careers. In addition to the talks there was a graduate student poster session and tutorials on topics in mathematics andmore » computer science. These talks, presentations, and discussions brought a broader perspective to the critical issues involving minority participation in mathematics.« less

Lack of association between uncoupling protein-2 Ala55Val polymorphism and incident diabetes in the atherosclerosis risk in communities study.

PubMed

Bielinski, Suzette J; Pankow, James S; Boerwinkle, Eric; Bray, Molly S; Kao, W H Linda; Folsom, Aaron R

2008-09-01

Type 2 diabetes mellitus (T2DM) is characterized by impaired insulin secretion, peripheral insulin resistance, and increased hepatic glucose production. Genes that contribute to genetic susceptibility to T2DM function in numerous biochemical pathways. Uncoupling protein-2 (UCP2) functions as a negative regulator of insulin secretion. Animal studies show induction of UCP2 plays a pathogenic role in the progression of obesity-induced T2DM and some human studies have shown an association between a common UCP2 polymorphism, Ala55Val (rs660339), and T2DM, obesity, and resting metabolic rate with the Val/Val genotype conferring increased risk. We investigated the relationship between the Ala55Val variant and incidence of T2DM among 12,056 participants in the Atherosclerosis Risk in Communities (ARIC) Study aged 45-64 years at baseline. Incident T2DM (n = 1,406) cases were identified over 9 years of follow-up. The Val55 allele frequency was 44% in blacks and 41% in whites. The rate of T2DM per 1,000 person was 15.0, 15.6, and 15.6 yearsfor Ala/Ala, Ala/Val, and Val/Val genotypes, respectively. We found no significant association between UCP2 genotypes and incident T2DM in the whole cohort, in race-gender subgroups, or in categories of body mass index (normal, overweight and obese). The Ala55Val polymorphism of UCP2 was not associated with incident T2DM in the ARIC cohort.

Proceedings of the Annual Mid-South Instructional Technology Conference (6th, Murfreesboro, Tennessee, April 8-10, 2001).

ERIC Educational Resources Information Center

Middle Tennessee State Univ., Murfreesboro.

This proceedings of the sixth annual Mid-South Instructional Technology Conference contains the following papers: "They're Not Just Big Kids: Motivating Adult Learners" (Karen Jarrett Thoms); "A Computer Integrated Biology Laboratory Experience" (James B. Kring); "Building Web Sites for Mathematics Courses: Some Answers to…

Research in Medical Education: Proceedings of the Annual Conference (38th, Washington, DC, October 25-27, 1999).

ERIC Educational Resources Information Center

Anderson, M. Brownell, Ed.

1999-01-01

The Proceedings of the 38th Annual Conference on Research in Medical Education (Washington, DC, October 25-27, 1999) contain 43 research papers on innovative curricula, diagnostic reasoning, student evaluations of faculty, practicing physicians, prediction, licensing examinations, admissions, faculty development, managed care, technology-enhanced…

Alpha-linolenic acid (ALA) is inversely related to development of adiposity in school-age children

PubMed Central

Perng, Wei; Villamor, Eduardo; Mora-Plazas, Mercedes; Marin, Constanza; Baylin, Ana

2015-01-01

Background/Objectives Studies in adults indicate that dietary polyunsaturated fatty acid (PUFA) composition may play a role in development of adiposity. Because adipocyte quantity is established between late childhood and early adolescence, understanding the impact of PUFAs on weight gain during the school-age years is crucial to developing effective interventions. Subjects/Methods We quantified N-3 and N-6 PUFAs in serum samples of 668 Colombian schoolchildren aged 5–12 years at the time of recruitment into a cohort study, using gas-liquid chromatography. Serum concentrations of N-3 (ALA, EPA, DHA) and N-6 PUFAs (LA, GLA, DGLA, AA) were determined as % total fatty acids. Children’s anthropometry was measured annually for a median of 30 months. We used mixed-effects models with restricted cubic splines to construct population body mass index-for-age z-score (BAZ) growth curves for age-and sex-specific quartiles of each PUFA. Results N-3 ALA was inversely related to BAZ gain after adjustment for sex, baseline age and weight status, and household socioeconomic level. Estimated BAZ change between 6 and 14 years among children in the highest quartile of ALA compared to those in the lowest quartile was 0.45 (95% CI: 0.07, 0.83) lower (P-trend=0.006). Conclusions N-3 ALA may be protective against weight gain in school-age children. Whether improvement in PUFA status reduces adiposity in pediatric populations deserves evaluation in randomized trials. PMID:25271016

Institutional Research: Leadership through Excellence. North East Association for Institutional Research Annual Conference Proceedings (28th, Cambridge, Massachusetts, November 17-20, 2001).

ERIC Educational Resources Information Center

North East Association for Institutional Research.

The theme of the 2001 annual conference of the Northeast Association for Institutional Research was Institutional Research: Leadership through Excellence. These proceedings represent the intellectual content and insights shared during the conference. The papers are: (1) The Rocky Road to Graduation: An Academic Career Flow Model for Tracking…

A brief history of Forging New Frontiers, the annual conference of the Injury Free Coalition for Kids.

PubMed

Johnson, Estell Lenita; Barlow, Barbara

2016-10-01

The Injury Free Coalition for Kids Annual Conference has contributed to the dissemination of information pertaining to the development of the field of injury prevention. A content analysis was completed using conference agendas used during the span of 2005-2015, finding that more than 398 presentations covering a wide variety of injuries have taken place. Published work has appeared in the Journal of Trauma and there has been recognition of people who have contributed to the development of the field. Forging New Frontiers is a valuable tool for attendees to exchange information about injury prevention.

Highlights From the Third Annual Mayo Clinic Conference on Systems Engineering and Operations Research in Health Care

PubMed Central

Kamath, Janine R. A.; Osborn, John B.; Roger, Véronique L.; Rohleder, Thomas R.

2011-01-01

In August 2010, the Third Annual Mayo Clinic Conference on Systems Engineering and Operations Research in Health Care was held. The continuing mission of the conference is to gather a multidisciplinary group of systems engineers, clinicians, administrators, and academic professors to discuss the translation of systems engineering methods to more effective health care delivery. Education, research, and practice were enhanced via a mix of formal presentations, tutorials, and informal gatherings of participants with diverse backgrounds. Although the conference promotes a diversity of perspectives and methods, participants are united in their desire to find ways in which systems engineering can transform health care, especially in the context of health care reform and other significant changes affecting the delivery of health care. PMID:21803959

NASA/USRA University Advanced Design Program Fourth Annual Summer Conference

NASA Technical Reports Server (NTRS)

Alred, John

1988-01-01

The study topics cover a broad range of potential space and aeronautics projects which could be undertaken during a 20-30 year period beginning with the Space Station Initial Operating Configuration scheduled for the mid 1990's. Both manned and unmanned endeavors are embraced, and the systems approach to the design problem is emphasized. The student teams pursue the chosen problem during their senior year in a one or two semester capstone design course and submit a comprehensive written report at the conclusion of the project. Finally, student representatives from each of the universities summarize their work in oral presentations at the annual Summer Conference, held at one of the NASA centers and attended by the university faculty, NASA and USRA personnel, and aerospace industry representatives.

Variable Reporting by Authors Presenting Arthroplasty Research at Multiple Annual Conferences.

PubMed

Choo, Kevin J; Yi, Paul H; Burns, Robert; Mohan, Rohith; Wong, Kevin

2017-01-01

Prior studies have demonstrated discrepancies in financial conflict of interest (COI) disclosure among authors presenting research at multiple spine and sports medicine conferences. The purpose of this study was to quantify the variability of self-reported financial disclosures of individual authors presenting at multiple arthroplasty conferences during the same year. The author disclosure information published for the 2012 annual meetings of the American Academy of Orthopaedic Surgeons (AAOS), American Association of Hip and Knee Surgeons, the Hip Society, and the Knee Society were compiled. We tabulated the author disclosures, the number of companies/entities represented, and the types of disclosures reported. The disclosures made by authors presenting at more than one meeting were then compared for discrepancies. Of the 209 authors who presented at both the AAOS and American Association of Hip and Knee Surgeons meetings, 79 (37.79%) demonstrated discrepancies in their disclosures with 7 (8.8%) reporting no disclosures to the AAOS. Of the 84 authors who presented at both the AAOS and Hip Society meetings, 1 (1.19%) had discrepancies in their disclosures. Of the 52 authors who presented at both the AAOS and Knee Society meetings, 2 (3.84%) had discrepancies in their disclosures. There is variability in reported financial COIs by authors presenting at multiple arthroplasty conferences within the same year. Further work is warranted to improve transparency of COI disclosures among arthroplasty surgeons presenting research at national meetings. Copyright © 2016 Elsevier Inc. All rights reserved.

Developments in School Finance. Fiscal Proceedings from the Annual NCES State Data Conference (July 28-30, 1993).

ERIC Educational Resources Information Center

Fowler, William J., Jr., Ed.

State legislation and new funding mechanisms have changed the traditional landscape of school financing. This publication contains papers by presenters at the annual National Center for Education Statistics (NCES) State Data Conference. Following the foreword, acknowledgments, introduction, and overview, the papers include: (1) "Testimony to the…

Ready, Set, Conference! Mastering the Logistics

ERIC Educational Resources Information Center

McGuire, Margaret

2005-01-01

Planning to have a successful NAEYC Annual Conference experience is similar to preparing for a day of bargain shopping. In this article, the author describes how to get the most out of NAEYC's Annual Conference by analyzing their goals, preparing ahead, and being flexible. As a veteran conference attendee, the author learned from her mistakes and…

Monitoring blood flow responses during topical ALA-PDT

PubMed Central

Becker, Theresa L.; Paquette, Anne D.; Keymel, Kenneth R.; Henderson, Barbara W.; Sunar, Ulas

2011-01-01

Photodynamic therapy (PDT) using topical 5-aminolevulinic acid (ALA) is currently used as a clinical treatment for nonmelanoma skin cancers. In order to optimize PDT treatment, vascular disruption early in treatment must be identified and prevented. We present blood flow responses to topical ALA-PDT in a preclinical model and basal cell carcinoma patients assessed by diffuse correlation spectroscopy (DCS). Our results show that ALA-PDT induced early blood flow changes and these changes were irradiance dependent. It is clear that there exists considerable variation in the blood flow responses in patients from lesion to lesion. Monitoring blood flow parameter may be useful for assessing ALA-PDT response and planning. PMID:21326642

PREFACE: Selected papers from the Fourth Annual q-bio Conference on Cellular Information Processing Selected papers from the Fourth Annual q-bio Conference on Cellular Information Processing

NASA Astrophysics Data System (ADS)

Nemenman, Ilya; Faeder, James R.; Hlavacek, William S.; Jiang, Yi; Wall, Michael E.; Zilman, Anton

2011-10-01

Summary This special issue consists of 11 original papers that elaborate on work presented at the Fourth Annual q-bio Conference on Cellular Information Processing, which was held on the campus of St John's College in Santa Fe, New Mexico, USA, 11-14 August 2010. Now in its fourth year, the q-bio conference has changed considerably over time. It is now well established and a major event in systems biology. The 2010 conference saw attendees from all continents (except Antarctica!) sharing novel results and participating in lively discussions at both the oral and poster sessions. The conference was oversubscribed and grew to 27 contributed talks, 16 poster spotlights and 137 contributed posters. We deliberately decreased the number of invited speakers to 21 to leave more space for contributed presentations, and the attendee feedback confirmed that the choice was a success. Although the q-bio conference has grown and matured, it has remained true to the original goal of being an intimate and dynamic event that brings together modeling, theory and quantitative experimentation for the study of cell regulation and information processing. Funded in part by a grant from NIGMS and by DOE funds through the Los Alamos National Laboratory Directed Research and Development program, the conference has continued to exhibit youth and vigor by attracting (and partially supporting) over 100 undergraduate, graduate and postdoctoral researchers. The associated q-bio summer school, which precedes the conference each year, further emphasizes the development of junior scientists and makes q-bio a singular event in its impact on the future of quantitative biology. In addition to an increased international presence, the conference has notably diversified its demographic representation within the USA, including increased participation from the southeastern corner of the country. One big change in the conference this year is our new publication partner, Physical Biology. Although we are very

Making Our Presence Felt: Librarians Come to Washington and Get Their Concerns on the Agenda

ERIC Educational Resources Information Center

Albanese, Andrew; Bardales, Aida; Berry, John N., III; Datema, Jay; Fialkoff, Francine; Fox, Bette-Lee; Oder, Norman; Rogers, Michael; Williams, Wilda

2007-01-01

This article presents the highlights of the 2007 American Library Association (ALA) annual conference held at the Washington Convention Center in Washington, D.C. Hundreds of librarians showed up early for a day of service, volunteering in libraries, schools, and other Washington-area institutions. As the conference wound down, some 2000…

Proceedings of the International Academy for Information Management Annual Conference (15th, Brisbane, Australia, December 6-10, 2000).

ERIC Educational Resources Information Center

International Academy for Information Management.

This document presents proceedings from the International Academy for Information Management (IAIM) annual conference, held December 6-10, 2000 in Brisbane, Australia. Papers include: "Metacognitive Miscalibration and Underachievement in a Computer Literacy Course: Some Preliminary Observations" (Deborah K. Smith, William Wittman, C. Bryan…

Proceedings of the International Academy for Information Management Annual Conference (12th, Atlanta, Georgia, December 12-14, 1997).

ERIC Educational Resources Information Center

Rogers, Camille, Ed.

This proceedings includes 62 papers presented at the 12th annual International Academy for Information Management (IAIM) conference. Topics of papers include: electronic undergraduate courses; software for teaching change management; cooperative projects; experiential learning; World Wide Web applications; internationalization of the information…

Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference on Undergraduate Teaching of Psychology (19th, Monticello, New York, April 6-8, 2005)

ERIC Educational Resources Information Center

Zaromatidis, Katherine, Ed.; Oswald, Patricia A., Ed.; Levine, Judith R., Ed.; Indenbaum, Gene, Ed.

2005-01-01

The 19th Annual Conference on Undergraduate Teaching of Psychology was held on April 6-8, 2005 at Kutsher's Country Club in Monticello, New York. The conference was sponsored by the Psychology Department of the State University of New York at Farmingdale. The conference featured two keynote speakers--Dr. James Naire, sponsored by Wadsworth…

Women in Engineering Program Advocates Network (WEPAN): Evaluation of the seventh annual conference

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brainard, S.G.

1996-08-01

The primary goals of the 1996 WEPAN Conference were to: (1) Conduct technical and programmatic seminars for institutions desiring to initiate, replicate, or expand women in engineering programs; (2) Provide assistance in fundraising and grant writing; (3) Profile women in engineering programs of excellence; (4) Sponsor inspiring, knowledgeable and motivational keynote speakers; and, (5) Offer a series of workshops focused on topics such as: establishing partnerships with industry, current research findings, retention strategies, issues affecting special populations, and early intervention techniques. In an effort to provide greater access for women to engineering careers, women in engineering program directors at Purduemore » University, Stevens Institute of Technology and the University of Washington joined together in 1990 to establish WEPAN, a national network of individuals interested in the recruitment, admission, retention, and graduation of women engineering students. This is the seventh year of operation. Success of this effort has been reflected in numerous ways: increased membership in the organization; increased number of women in engineering programs; increased number of women graduating in engineering; and grants from the U.S. Department of Energy, the National Science Foundation, the Alfred P. Sloan Foundation, the AT&T Foundation, and many other corporations to carry out the goals of WEPAN. The Seventh Annual Women in Engineering Conference entitled, Capitalizing on Today`s Challenges, was held in Denver, Colorado on June 1-4, 1996 at the Hyatt Regency. The conference brought together representatives from academia, government, and industry and examined current issues and initiatives for women in technology, science, and education. Building on the successes of the previous conferences, the seventh conference offered a new variety of speakers and topics.« less

Career Planning and Placement in the Small College. Proceedings of the Annual Conference (3rd, Alma College, Michigan, May 9-11, 1979).

ERIC Educational Resources Information Center

Riser-Schock, Ginny, Ed.

Seventeen presentations made at the third annual conference on career planning and placement in the small college are presented. The thrust of the conference was aimed at cooperation and sharing of ideas of professionals working in one- or two-person offices within the constraints of a limited budget. Among the presentations included are (1)…

The Annual Pennsylvania Conference on Postsecondary Occupational Education: New Federal Legislation Emphasis and Postsecondary Vocational Education (10th).

ERIC Educational Resources Information Center

Wircenski, Jerry L., Ed.; And Others

Papers from the Tenth Annual Pennsylvania Conference on Postsecondary Occupational Education, which focused on new federal emphasis and postsecondary vocational education, are presented. Edited versions of discussions of the topics are also included. The following papers are included: "Adults--An Underdeveloped National Resource," by…

Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference on Undergraduate Teaching of Psychology (23rd, Tarrytown, New York, March 20-21, 2009)

ERIC Educational Resources Information Center

Howell-Carter, Marya, Ed.; Gonder, Jennifer, Ed.

2009-01-01

The document is a summary of the conference proceedings for the 23rd Annual Farmingdale State College Teaching of Psychology Conference held on March 20-21, 2009 at the DoubleTree Hotel in Tarrytown, New York. The conference featured a keynote address by Dr. Jeffrey Nevid on Reaching and teaching the millennials: Helping today's students become…

Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference on Undergraduate Teaching of Psychology (21st, Kerhonkson, New York, March 28-30, 2007)

ERIC Educational Resources Information Center

Zaromatidis, Katherine, Ed.; Oswald, Patricia A., Ed.; Levine, Judith R., Ed.; Indenbaum, Gene, Ed.

2007-01-01

The 21st Annual Conference on Undergraduate Teaching of Psychology was held on March 28-30, 2007 at Hudson Valley Resort and Day Spa in Kerhonkson, New York. The conference was sponsored by the Psychology Department of Farmingdale State College. The conference included twenty five presentations and ten of these are included in these proceedings.…

North East Association for Institutional Research Annual Conference Proceedings (29th, Annapolis, Maryland, November 16-19, 2002).

ERIC Educational Resources Information Center

North East Association for Institutional Research.

This proceedings contains papers from the 2002 annual conference of the Northeast Association for Institutional Research, a meeting devoted to assessment in the 21st century and the challenges that face institutional research. The papers are: (1) "Putting Community College Enrollment Trends in Perspective by the Use of Census Data and Market…

Reading and Reality. Proceedings of the Annual Reading Conference (14th, Terre Haute, Indiana, June 14, 1984).

ERIC Educational Resources Information Center

Gibbs, Vanita M., Comp.; Waterman, David C., Comp.

Intended for reading teachers, this pamphlet contains the presentations of the 14th annual reading conference at Indiana State University, beginning with opening remarks by David C. Waterman and welcoming comments by J. Stephen Hazlett. In the opening address, "What Good is Comprehension without Composition?" by Sharon and David Moore, the role of…

Rational design of HIV vaccine and microbicides: report of the EUROPRISE annual conference.

PubMed

Wahren, Britta; Biswas, Priscilla; Borggren, Marie; Coleman, Adam; Da Costa, Kelly; De Haes, Winni; Dieltjens, Tessa; Dispinseri, Stefania; Grupping, Katrijn; Hallengärd, David; Hornig, Julia; Klein, Katja; Mainetti, Lara; Palma, Paolo; Reudelsterz, Marc; Seifried, Janna; Selhorst, Philippe; Sköld, Annette; Uchtenhagen, Hannes; van Gils, Marit J; Weber, Caroline; Shattock, Robin; Scarlatti, Gabriella

2010-07-26

EUROPRISE is a Network of Excellence sponsored from 2007 to 2011 by the European Commission within the 6th Framework Program. The Network encompasses a wide portfolio of activities ranging from an integrated research program in the field of HIV vaccines and microbicides to training, dissemination and advocacy. The research program covers the whole pipeline of vaccine and microbicide development from discovery to early clinical trials. The Network is composed of 58 partners representing more than 65 institutions from 13 European countries; it also includes three major pharmaceutical companies (GlaxoSmithKline, Novartis and Sanofi-Pasteur) involved in HIV microbicide and vaccine research. The Network displays a dedicated and informative web page: http://www.europrise.org. Finally, a distinguishing trait of EUROPRISE is its PhD School of students from across Europe, a unique example in the world of science aimed at spreading excellence through training. EUROPRISE held its second annual conference in Budapest in November, 2009. The conference had 143 participants and their presentations covered aspects of vaccine and microbicide research, development and discovery. Since training is a major task of the Network, the students of the EUROPRISE PhD program summarized certain presentations and their view of the conference in this paper.

Rational design of HIV vaccine and microbicides: report of the EUROPRISE annual conference

PubMed Central

2010-01-01

EUROPRISE is a Network of Excellence sponsored from 2007 to 2011 by the European Commission within the 6th Framework Program. The Network encompasses a wide portfolio of activities ranging from an integrated research program in the field of HIV vaccines and microbicides to training, dissemination and advocacy. The research program covers the whole pipeline of vaccine and microbicide development from discovery to early clinical trials. The Network is composed of 58 partners representing more than 65 institutions from 13 European countries; it also includes three major pharmaceutical companies (GlaxoSmithKline, Novartis and Sanofi-Pasteur) involved in HIV microbicide and vaccine research. The Network displays a dedicated and informative web page: http://www.europrise.org. Finally, a distinguishing trait of EUROPRISE is its PhD School of students from across Europe, a unique example in the world of science aimed at spreading excellence through training. EUROPRISE held its second annual conference in Budapest in November, 2009. The conference had 143 participants and their presentations covered aspects of vaccine and microbicide research, development and discovery. Since training is a major task of the Network, the students of the EUROPRISE PhD program summarized certain presentations and their view of the conference in this paper. PMID:20659333

National Conference on Library Statistics (Chicago, June 6-8, 1966).

ERIC Educational Resources Information Center

Trezza, Alphonse F., Ed.; Beasley, James, Ed.

Attended by representatives of American Library Association (ALA) divisions and committees, other national library associations, state library agencies, library schools, and all types of libraries, this conference was held to discuss: (1) the program of the National Center for Educational Statistics (USOE) as it pertains to libraries; (2) the…

Functional analysis of the missense APOC3 mutation Ala23Thr associated with human hypotriglyceridemia.

PubMed

Sundaram, Meenakshi; Zhong, Shumei; Bou Khalil, Maroun; Zhou, Hu; Jiang, Zhenghui G; Zhao, Yang; Iqbal, Jahangir; Hussain, M Mahmood; Figeys, Daniel; Wang, Yuwei; Yao, Zemin

2010-06-01

We have shown that expression of apolipoprotein (apo) C-III promotes VLDL secretion from transfected McA-RH7777 cells under lipid-rich conditions. To determine structural elements within apoC-III that confer to this function, we contrasted wild-type apoC-III with a mutant Ala23Thr originally identified in hypotriglyceridemia subjects. Although synthesis of [(3)H]glycerol-labeled TAG was comparable between cells expressing wild-type apoC-III (C3wt cells) or Ala23Thr mutant (C3AT cells), secretion of [(3)H]TAG from C3AT cells was markedly decreased. The lowered [(3)H]TAG secretion was associated with an inability of C3AT cells to assemble VLDL(1). Moreover, [(3)H]TAG within the microsomal lumen in C3AT cells was 60% higher than that in C3wt cells, yet the activity of microsomal triglyceride-transfer protein in C3AT cells was not elevated. The accumulated [(3)H]TAG in C3AT microsomal lumen was mainly associated with lumenal IDL/LDL-like lipoproteins. Phenotypically, this [(3)H]TAG fractionation profiling resembled what was observed in cells treated with brefeldin A, which at low dose specifically blocked the second-step VLDL(1) maturation. Furthermore, lumenal [(35)S]Ala23Thr protein accumulated in IDL/LDL fractions and was absent in VLDL fractions in C3AT cells. These results suggest that the presence of Ala23Thr protein in lumenal IDL/LDL particles might prevent effective fusion between lipid droplets and VLDL precursors. Thus, the current study reveals an important structural element residing within the N-terminal region of apoC-III that governs the second step VLDL(1) maturation.

Literacy: Traditional, Cultural, Technological. Selected Papers from the Annual Conference of the International Association of School Librarianship (23rd, Pittsburgh, Pennsylvania, July 17-22, 1994).

ERIC Educational Resources Information Center

International Association of School Librarianship, Kalamazoo, MI.

Themes of the 23rd Annual International Association of School Librarianship conference included "Traditional Literacy,""The Current Status of Libraries,""Literacy in a Technological World," and "Preserving Cultural and Historical Literacy." The following papers were presented at the conference: (1)…

The Benefits of Attending the Annual Biomedical Research Conference for Minority Students (ABRCMS): The Role of Research Confidence

ERIC Educational Resources Information Center

Casad, Bettina J.; Chang, Amy L.; Pribbenow, Christine M.

2016-01-01

The Annual Biomedical Research Conference for Minority Students (ABRCMS) is designed to support undergraduate students' professional development as future scientists. Juniors, seniors, and postbaccalaureates who attended ABRCMS during 2008-2011 were emailed a link to an online questionnaire in which they reported their experiences at the…

Continuous bioprocessing: the real thing this time? 10(th) Annual bioProcessUK Conference, December 3-4, 2013, London, UK.

PubMed

Farid, Suzanne S; Thompson, Bill; Davidson, Andrew

2014-01-01

The Annual bioProcessUK Conference has acted as the key networking event for bioprocess scientists and engineers in the UK for the past 10 years. The following article is a report from the sessions that focused on continuous bioprocessing during the 10(th) Annual bioProcessUK Conference (London, December 2013). These sessions were organized by the 'EPSRC Centre for Innovative Manufacturing in Emergent Macromolecular Therapies' hosted at University College London. A plenary lecture and workshop provided a forum for participants to debate topical issues in roundtable discussions with industry and academic experts from institutions such as Genzyme, Janssen, Novo Nordisk, Pfizer, Merck, GE Healthcare and University College London. The aim of these particular sessions was to understand better the challenges and opportunities for continuous bioprocessing in the bioprocessing sector.

5. annual clean coal technology conference: powering the next millennium. Vol.1

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-07-01

The Fifth Annual Clean Coal Technology Conference focuses on presenting strategies and approaches that will enable clean coal technologies to resolve the competing, interrelated demands for power, economic viability, and environmental constraints associated with the use of coal in the post-2000 era. The program addresses the dynamic changes that will result from utility competition and industry restructuring, and to the evolution of markets abroad. Current projections for electricity highlight the preferential role that electric power will have in accomplishing the long-range goals of most nations. Increased demands can be met by utilizing coal in technologies that achieve environmental goals whilemore » keeping the cost- per-unit of energy competitive. Results from projects in the DOE Clean Coal technology Demonstration Program confirm that technology is the pathway to achieving these goals. The industry/government partnership, cemented over the past 10 years, is focused on moving the clean coal technologies into the domestic and international marketplaces. The Fifth Annual Clean Coal Technology Conference provides a forum to discuss these benchmark issues and the essential role and need for these technologies in the post-2000 era. This volume contains papers presented at the plenary session and panel sessions on; international markets for clean coal technologies (CCTs); role of CCTs in the evolving domestic electricity market; environmental issues affecting CCT deployment; and CCT deployment from today into the next millennium. In addition papers presented at the closing plenary session on powering the next millennium--CCT answers the challenge are included. Selected papers have been processed for inclusion in the Energy Science and Technology database.« less

Summary Report of the Title VI-G Network Third Annual Conference. (Minneapolis, Minnesota, December 5-8, 1977).

ERIC Educational Resources Information Center

Network of Innovative Schools, Inc., Andover, MA.

Presented is the summary report of the Third Annual Conference of the Title VI-G Network which was designed to update learning disability (LD) professionals on pertinent program and education developments, to inform them of future trends and plans, and to offer concrete help in their present work. Introductory sections provide a schedule of the…

AISES 1995 annual conference ($10,000), AISES scholarship fund ($5,000). Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1997-10-30

The conference took place in Detroit, MI, November 9--12, 1995, at the COBO Convention Center. This educational event and career fair serve as part of the reward for students pursuing or about to complete their education. The community of peers, professionals, elders, family and mentors embrace the students` ambitions and celebrate the students` accomplishments. For students who might otherwise feel disconnected while in school, the annual gathering at the conference is a vital part of maintaining their motivation and inspiring perseverance. The 1995 Conference attendance was 1,900 students and professionals. Some 230 companies, government agencies, universities and organizations were representedmore » at the Career Fair where students gathered information regarding employment and educational opportunities. In an effort to provide as many opportunities as possible for students and recruiters, a networking room was available throughout the conference for interviewing, networking and socializing. Student poster research presentations were displayed in this area as well. A Job Information Center was also open to provide announcements for specific job opening as well as cross-referenced lists of majors/disciplines and the organizations that recruit in those areas of interest. Total scholarship disbursements for 1995 exceeded $600,000. Scholarships were granted to some 375 students in awards of $1,000 to $4,000. AISES scholarships are awarded to American Indian/Alaska Native undergraduate and graduate students who are members of AISES majoring in the sciences, engineering, health-related fields, business, natural resources, math and science secondary education, and energy resource management. Scholarship are awarded in recognition of students` leadership and academic achievements.« less

The AT Odyssey Continues. Proceedings of the RESNA 2001 Annual Conference (Reno, Nevada, June 22-26, 2001). Volume 21.

ERIC Educational Resources Information Center

Simpson, Richard, Ed.

These proceedings of the annual RESNA (Association for the Advancement of Rehabilitation Technology) conference include more than 200 presentations on all facets of assistive technology, including concurrent sessions, scientific platform sessions, interactive poster presentations, computer demonstrations, and the research symposia. The scientific…

[The United Nations confronts the challenges of a changing world: the 49th Annual DPI/NGO Conference].

PubMed

Dickson, K

1997-03-01

The United Nations (UN), previously considered a forum exclusively for sovereign governments, has changed over time in tune with various political, economic, social, and cultural phenomena. One of these is the growing presence of nongovernmental organizations (NGOs) in international agencies and activities. The 49th Annual Conference of the Department of Public Information and NGOs, held at UN headquarters on 10 September 1996, analyzed the extent to which the UN is allowing NGOs to participate in its discussions of policy, institutional reform, and field operations. The issues discussed at the Conference and the challenges that face the UN in a changing world from the subject of this report.

"Reachout." Proceedings of the Annual Conference of the Associations of College Unions--International (48th, White Sulphur Springs, West Virginia, March 21-24, 1971).

ERIC Educational Resources Information Center

Association of Coll. Unions-International, Ithaca, NY.

This document presents the speeches and programs that comprised the 48th Annual Conference of the Associations of College Unions-International. The conference was divided into 6 major parts. The first part was concerned with the administrative organization of the college union, taking into consideration the student-faculty partnership organization…

Mathematics: Essential Research, Essential Practice. Volumes 1 and 2. Proceedings of the 30th Annual Conference of the Mathematics Education Research Group of Australasia

ERIC Educational Resources Information Center

Watson, Jane, Ed.; Beswick, Kim, Ed.

2007-01-01

This is a record of the proceedings of the 30th annual conference of the Mathematics Education Research Group of Australasia (MERGA). The theme of the conference is "Mathematics: Essential research, essential practice." The theme draws attention to the importance of developing and maintaining links between research and practice and…

Proceedings of the Annual Southern Research Conference in Agricultural Education (30th, Lubbock, Texas, July 21-23, 1981).

ERIC Educational Resources Information Center

Cepica, M. J.; And Others

These proceedings contain 20 presentations and reports made during the 30th Annual Research Conference in Agricultural Education in Lubbock, Texas. The keynote address on importance of research to agricultural education is followed by 16 research papers reporting on analysis of student teacher morale before and after student teaching;…

The Reading Environment; Proceedings of the Annual Reading Conference (8th, Terre Haute, Indiana, June 15-16, 1978).

ERIC Educational Resources Information Center

Waterman, David C., Comp.; Gibbs, Vanita M., Comp.

The papers presented in this annual reading conference report focus on various aspects of the topic, "The Reading Environment." The opening address advocates establishing reading programs that correspond to the developmental stages of individual children--programs that consider the needs of the whole child. The other papers delivered at the…

Spotlight on Technology. Proceedings of the RESNA '99 Annual Conference (Long Beach, California, June 25-29, 1999). Volume 19.

ERIC Educational Resources Information Center

Sprigle, Stephen, Ed.

This book contains the proceedings of the annual RESNA (Association for the Advancement of Rehabilitation Technology) conference, which focused on technology and individuals with disabilities. Papers and presentations are grouped into the following nine major categories: (1) assistive technology and cognitive disabilities; (2) augmentative and…

Evidence for a Contribution of ALA Synthesis to Plastid-To-Nucleus Signaling

PubMed Central

Czarnecki, Olaf; Gläßer, Christine; Chen, Jin-Gui; Mayer, Klaus F. X.; Grimm, Bernhard

2012-01-01

The formation of 5-aminolevulinic acid (ALA) in tetrapyrrole biosynthesis is widely controlled by environmental and metabolic feedback cues that determine the influx into the entire metabolic path. Because of its central role as the rate-limiting step, we hypothesized a potential role of ALA biosynthesis in tetrapyrrole-mediated retrograde signaling and exploited the direct impact of ALA biosynthesis on nuclear gene expression (NGE) by using two different approaches. Firstly, the Arabidopsis gun1, hy1 (gun2), hy2 (gun3), gun4 mutants showing uncoupled NGE from the physiological state of chloroplasts were thoroughly examined for regulatory modifications of ALA synthesis and transcriptional control in the nucleus. We found that reduced ALA-synthesizing capacity is common to analyzed gun mutants. Inhibition of ALA synthesis by gabaculine (GAB) that inactivates glutamate-1-semialdehyde aminotransferase and ALA feeding of wild-type and mutant seedlings corroborate the expression data of gun mutants. Transcript level of photosynthetic marker genes were enhanced in norflurazon (NF)-treated seedlings upon additional GAB treatment, while enhanced ALA amounts diminish these RNA levels in NF-treated wild-type in comparison to the solely NF-treated seedlings. Secondly, the impact of posttranslationally down-regulated ALA synthesis on NGE was investigated by global transcriptome analysis of GAB-treated Arabidopsis seedlings and the gun4-1 mutant, which is also characterized by reduced ALA formation. A common set of significantly modulated genes was identified indicating ALA synthesis as a potential signal emitter. The over-represented gene ontology categories of genes with decreased or increased transcript abundance highlight a few biological processes and cellular functions, which are remarkably affected in response to plastid-localized ALA biosynthesis. These results support the hypothesis that ALA biosynthesis correlates with retrograde signaling-mediated control of NGE

Proceedings of the Annual RAND-China Reform Forum Conference (6th) Held in Santa Monica, California on August 28-29, 2003

DTIC Science & Technology

2005-01-01

documents for commercial use. Limited Electronic Distribution Rights For More Information CHILD POLICY CIVIL JUSTICE EDUCATION ENERGY AND ENVIRONMENT HEALTH...Reform Forum Conference. August 28-29, 2003 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK...have been reviewed and approved by RAND Science and Technology. Proceedings of the 6th Annual RAND–China Reform Forum Conference August 28–29

Developments in School Finance: 2004. Fiscal Proceedings from the Annual State Data Conference of July 2004. NCES 2005-865

ERIC Educational Resources Information Center

Fowler, William J., Jr., Ed.

2005-01-01

This report contains papers presented at the 2004 annual NCES Summer Data Conference. Discussions and presentations dealt with such topics as measuring school efficiency, analyzing the return on education investment, calculating education costs per student, and assessing the financial condition of school districts. The following papers are…

Selections from the ABC 2015 Annual Conference, Seattle, Washington: Pitching Fish and Innovative Oral and Written Business Communication Assignments

ERIC Educational Resources Information Center

Whalen, D. Joel, Ed.

2016-01-01

This article, the first of a two-part series, presents teaching 10 innovations from the 2015 Association for Business Communication's 80th annual conference. The creative new assignments offered here include building listening skills by journaling, oral interpretation, positive message framing, storytelling, delivering bad news, persuasive…

Report on annual utility oil buyers conference

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stambler, K.

1994-08-01

What was discussed at this year`s Utility Oil Buyers` Conference is summarized. This year`s conference was held in Boston and there were over 200 attendees representing over 130 different companies from the utility, oil trading, consulting and inspection industries. Attendees for this year`s came from as far away as Italy and Argentina. The mood at this year`s conference was somber, as each sector is feeling the effects of the decline in residual fuel oil demand--due to natural gas displacement, non-utility generation and an economy that is still lethargic. The topics that were covered ranged from {open_quotes}Life after Order 636{close_quotes} tomore » {open_quotes}Does Residual Fuel Oil Have a Future in a Utility Steam Boiler?{close_quotes} to {open_quotes}The Future of Shipping after OPA of 1990.{close_quotes} In addition, there were several topics that have been or will be covered at this conference.« less

The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on glucose/insulin metabolism interact with prenatal exposure to famine.

PubMed

de Rooij, Susanne R; Painter, Rebecca C; Phillips, David I W; Osmond, Clive; Tanck, Michael W T; Defesche, Joep C; Bossuyt, Patrick M M; Michels, Robert P J; Bleker, Otto P; Roseboom, Tessa J

2006-05-01

An adverse fetal environment may permanently modify the effects of specific genes on glucose tolerance, insulin secretion, and insulin sensitivity. In the present study, we assessed a possible interaction of the peroxisome proliferator-activated receptor (PPAR)-gamma2 Pro12Ala polymorphism with prenatal exposure to famine on glucose and insulin metabolism. We measured plasma glucose and insulin concentrations after an oral glucose tolerance test and determined the PPAR-gamma2 genotype among 675 term singletons born around the time of the 1944-1945 Dutch famine. A significant interaction effect between exposure to famine during midgestation and the PPAR-gamma2 Pro12Ala polymorphism was found on the prevalence of impaired glucose tolerance and type 2 diabetes. The Ala allele of the PPAR-gamma2 gene was associated with a higher prevalence of impaired glucose tolerance and type 2 diabetes but only in participants who had been prenatally exposed to famine during midgestation. Similar interactions were found for area under the curve for insulin and insulin increment ratio, which were lower for Ala carriers exposed to famine during midgestation. The effects of the PPAR-gamma2 Pro12Ala polymorphism on glucose and insulin metabolism may be modified by prenatal exposure to famine during midgestation. This is possibly due to a combined deficit in insulin secretion, as conferred by pancreatic beta-cell maldevelopment and carrier type of the Ala allele in the PPAR-gamma2 gene.

Pharmaceutical Pricing and Market Access Outlook Europe 2010-HealthNetwork Communications' fourth annual conference. 24-25 March 2010, London, UK.

PubMed

Ogbighele, Erhimuvi

2010-05-01

The HealthNetwork Communications' Fourth Annual Conference on Pharmaceutical Pricing and Market Access Outlook Europe 2010, held in London, included topics covering the challenges facing the pharmaceutical industry, specifically related to pricing and reimbursement, and demonstrating the value of a pharmaceutical. This conference report highlights selected presentations on a global perspective on pricing and reimbursement, with an analysis of the specific, unique challenges in the six major markets, Europe, the US, Canada, Germany, the UK and Japan, and a discussion of the benefits of risk-sharing schemes.

Proceedings of the Annual National Conference for Child Care Workers (2nd, Valley Forge, PA, October 9-12, 1980).

ERIC Educational Resources Information Center

Powell, Norman W., Jr., Ed.

The speeches, papers, and workshops descriptions presented at the second annual National Conference for Child Care Workers are presented. Several issues relating to child care supervision, child care work, and child development are considered along with the management of group living environments and various aspects of supervision. Job…

4th Annual SATN Conference 2011: Curriculum Transformation at Universities of Technology: Towards Development of New Generation Universities

ERIC Educational Resources Information Center

Mthembu, T.

2012-01-01

The South African Technology Network (SATN) would like to thank the Editor of the "South African Journal of Higher Education" (SAJHE) for the opportunity to publish papers read at the 4th Annual SATN Conference that was hosted by Central University of Technology and held in Bloemfontein in November 2011. The journal makes it possible for…

Non-Traditional and Interdisciplinary Programs: Selected Papers from the Annual Conference of Non-Traditional and Interdisciplinary Programs (5th, Virginia Beach, Virginia, May 4-6, 1987).

ERIC Educational Resources Information Center

McGuinness, Kathleen, Comp.

Nearly 100 conference papers from the George Mason University annual conference on nontraditional and interdisciplinary studies are presented. The are grouped into 14 categories: (1) assessment of prior learning, which includes "Lifelong Learning: Integrating the Liberal Arts and Experience in Adult General Education" (J. Gary Bernhard) and…

Delta-ALA urine test

MedlinePlus

... hours. Normal value ranges may vary slightly from one lab to another. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean An increased level of urinary delta-ALA may ...

Nineteenth annual actinide separations conference: Conference program and abstracts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bronson, M.

This report contains the abstracts from the conference presentations. Sessions were divided into the following topics: Waste treatment; Spent fuel treatment; Issues and responses to Defense Nuclear Facility Safety Board 94-1; Pyrochemical technologies; Disposition technologies; and Aqueous separation technologies.

ALA-induced fluorescence in the canine oral cavity.

PubMed

Vaidyanathan, Vijay; Wiggs, Robert; Stohl, Josh; Baxi, Mehul

2006-06-01

We examined whether 5-aminolevulinic acid (ALA) could enhance the spectroscopic contrast between normal and diseased oral tissues, without prolonged photosensitivity. ALA is a promising photosensitizing agent. Adose of 25 mg/kg of ALA was administered intravenously to five dogs with gingivitis and three dogs with oral cancer, respectively. Fluorescence was recorded from the diseased sites in the oral cavity in addition to normal sites. ALA-induced proto-porphyrin IX fluorescence at all gingivitis sites reached a peak in 2-3 h and returned to baseline in 24 h. Fluorescence from the gingivitis site was observed earlier and was higher than the fluorescence from the normal site. For dogs with cancer, fluorescence from the cancerous sites occurred earlier in time compared to gingivitis sites and was comparatively higher in intensity. The fluorescence from the diseased sites was found to be higher than the normal site. Clinical and fluorescence data suggest that a dose of 25 mg/kg may be satisfactory for diagnostic purposes and would have minimal side effects.

Deeply Rooted, Branching Out, 1972-1997. Annual AEE International Conference Proceedings (25th, Asheville, North Carolina, November 23-26, 1997).

ERIC Educational Resources Information Center

Harwell, Rick, Ed.; Comstedt, Timothea, Ed.; Roberts, Nina, Ed.

This proceedings contains 36 papers presented at the 25th Annual Conference of the Association for Experiential Education. Papers are: "The Woods and the Trees: Interpreting Experiential Education for Schools and a Greater Audience" (Joanna Allen, John Hutchinson); "Adventure Programming & Prevention of Adolescent Problem…

Proceedings of the 8th Annual Summer Conference: NASA/USRA Advanced Design Program

NASA Technical Reports Server (NTRS)

1992-01-01

Papers presented at the 8th Annual Summer Conference are categorized as Space Projects and Aeronautics projects. Topics covered include: Systematic Propulsion Optimization Tools (SPOT), Assured Crew Return Vehicle Post Landing Configuration Design and Test, Autonomous Support for Microorganism Research in Space, Bioregenerative System Components for Microgravity, The Extended Mission Rover (EMR), Planetary Surface Exploration MESUR/Autonomous Lunar Rover, Automation of Closed Environments in Space for Human Comfort and Safety, Walking Robot Design, Extraterrestrial Surface Propulsion Systems, The Design of Four Hypersonic Reconnaissance Aircraft, Design of a Refueling Tanker Delivering Liquid Hydrogen, The Design of a Long-Range Megatransport Aircraft, and Solar Powered Multipurpose Remotely Powered Aircraft.

Teaching of Psychology: Ideas and Innovations. Proceedings and Papers of the Annual Conference on Undergraduate Teaching of Psychology (22nd, White Plains, New York, March 7-8, 2008)

ERIC Educational Resources Information Center

Oswald, Patricia A., Ed.; Zaromatidis, Katherine, Ed.; Levine, Judith R., Ed.; Indenbaum, Gene, Ed.

2008-01-01

The ND Annual Conference--Teaching of Psychology: Ideas and Innovations was held on March 7-8, 2008 at the Crowne Plaza in White Plains, New York. The conference was sponsored by the Psychology Department of Farmingdale State College. The conference featured Dr. Douglas Bernstein from the University of South Florida, Tampa as the keynote speaker.…

First Annual LGBT Health Workforce Conference: Empowering Our Health Workforce to Better Serve LGBT Communities.

PubMed

Sánchez, Nelson F; Sánchez, John Paul; Lunn, Mitchell R; Yehia, Baligh R; Callahan, Edward J

2014-03-01

The Institute of Medicine has identified significant health disparities and barriers to health care experienced by lesbian, gay, bisexual, and transgender (LGBT) populations. By lowering financial barriers to care, recent legislation and judicial decisions have created a remarkable opportunity for reducing disparities by making health care available to those who previously lacked access. However, the current health-care workforce lacks sufficient training on LGBT-specific health-care issues and delivery of culturally competent care to sexual orientation and gender identity minorities. The LGBT Healthcare Workforce Conference was developed to provide a yearly forum to address these deficiencies through the sharing of best practices in LGBT health-care delivery, creating LGBT-inclusive institutional environments, supporting LGBT personal and professional development, and peer-to-peer mentoring, with an emphasis on students and early career professionals in the health-care fields. This report summarizes the findings of the first annual LGBT Health Workforce Conference.

International Annual Conference (29th) of ICT Held in Karlsruhe, Federal Republic of Germany on June 30-July 3, 1998. Energetic Materials; Production, Processing and Characterization

DTIC Science & Technology

1998-06-26

The Final Proceedings for 29th International Annual Conference of ICT, 30 June 1998 - 3 July 1998. This is an interdisciplinary conference. Topics...include: (1) Components; (2) Particle Technology; (3) Synthesis, Production and Processing; (4) Characterization of Energetic Materials; (5) Safety Technology; and (6) Quality Assurance and Environmental Aspects.

Freedman's March.

ERIC Educational Resources Information Center

Library Journal, 2002

2002-01-01

Reports on the American Library Association's 2002 annual conference in Atlanta. Topics include incoming president Mitch Freedman's initiative to improve librarian salaries; author presentations; new technology, especially Amazon.com, and the library's role; ALA politics; intellectual freedom issues; salaries and recruiting; interoperability; and…

Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference on Undergraduate Teaching of Psychology (18th, Monticello, New York, March 24-26, 2004)

ERIC Educational Resources Information Center

Oswald, Patricia A., Ed.; Zaromatidis, Katherine, Ed.; Levine, Judith R., Ed.; Indenbaum, Gene, Ed.

2004-01-01

This document includes the proceedings and papers of the 18th Annual Conference on Undergraduate Teaching of Psychology, which was held on March 24-26, 2004 in Monticello, NY. The conference, which dealt with ideas and innovations in the teaching of psychology, was sponsored by the Psychology Department of the Farmingdale State University. The…

Current Explorations of Adult Learner: Implications for Mentoring and More. Adult Higher Education Alliance Annual Conference Proceedings (36th, Orlando, Florida, March 10-11, 2016)

ERIC Educational Resources Information Center

Elufiede, Kemi, Ed.; Flynn, Bonnie, Ed.

2016-01-01

The 36th Annual Adult Higher Education Alliance (AHEA) Conference was held on March 10-11, 2016 in Orlando, Florida, on the campus of the University of Central Florida. There were 48 presentations from scholars and practitioners from 20 states who participated in the conference. The contributions to these proceedings represent the best of the…

Semi-annual conference review January-June 2000

Treesearch

John K. Borchardt; Marguerite S. Sykes; Mahendra R. Doshi

2000-01-01

Conferences covered in this semiannual review include the TAPPI Recycling Symposium and the 9th PTS/CTP Deinking Symposium. The intent of this feature is to present a synopsis of the significant research results and industry ideas related to paper recycling reported at these conferences. Due to space constraints, we are not able to cover all of the presented papers in...

PIALA 2000: Libraries and Archives--Where Information and Language Literacy Begin [and] Engaged Readers and Writers in Multicultural Island Communities. Selected Papers from the 10th Pacific Islands Association of Libraries and Archives Conference Joint with the 13th Annual Regional Language Arts Conference (Tumon, Guam, November 9-11, 2000)

ERIC Educational Resources Information Center

Cohen, Arlene, Ed.; Quan, Clarisa G., Ed.

2004-01-01

This proceedings combines presentations from the jointly held 10th Annual PIALA 2000 Conference and the 13th Annual Regional Language Arts Conference. The volume begins with the welcoming remarks of Mary L. Silk, Christine Ku Scott-Smith, Antonio R. Umpingco, Delia Munoz Rosal, Lawrence Kasperbauer, Rosie Tainatongo, Richard S. Tom, Mary L.…

Shaping the Future of Mathematics Education. Proceedings of the Annual Conference of the Mathematics Education Research Group of Australasia (33rd, Freemantle, Western Australia, Australia, July 3-7, 2010)

ERIC Educational Resources Information Center

Sparrow, Len, Ed.; Kissane, Barry, Ed.; Hurst, Chris, Ed.

2010-01-01

These collected papers are a record of the proceedings of the 33rd Annual Conference of the Mathematics Education Research Group of Australasia entitled, "Shaping the Future of Mathematics Education." The conference is held in Fremantle, as was the previous conference a decade earlier. Keynote speakers are discussing issues that are emerging more…

Fluorescence-Guided Resection of Malignant Glioma with 5-ALA

PubMed Central

Kaneko, Sadahiro

2016-01-01

Malignant gliomas are extremely difficult to treat with no specific curative treatment. On the other hand, photodynamic medicine represents a promising technique for neurosurgeons in the treatment of malignant glioma. The resection rate of malignant glioma has increased from 40% to 80% owing to 5-aminolevulinic acid-photodynamic diagnosis (ALA-PDD). Furthermore, ALA is very useful because it has no serious complications. Based on previous research, it is apparent that protoporphyrin IX (PpIX) accumulates abundantly in malignant glioma tissues after ALA administration. Moreover, it is evident that the mechanism underlying PpIX accumulation in malignant glioma tissues involves an abnormality in porphyrin-heme metabolism, specifically decreased ferrochelatase enzyme activity. During resection surgery, the macroscopic fluorescence of PpIX to the naked eye is more sensitive than magnetic resonance imaging, and the alert real time spectrum of PpIX is the most sensitive method. In the future, chemotherapy with new anticancer agents, immunotherapy, and new methods of radiotherapy and gene therapy will be developed; however, ALA will play a key role in malignant glioma treatment before the development of these new treatments. In this paper, we provide an overview and present the results of our clinical research on ALA-PDD. PMID:27429612

33 CFR 110.194 - Mobile Bay, Ala., at entrance.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Mobile Bay, Ala., at entrance. 110.194 Section 110.194 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.194 Mobile Bay, Ala., at entrance. (a) The anchorage...

Higher Education 2000: What Will Be New? What Will Be Different? Proceedings of the Annual Accreditation and Quality Assurance Conference (1999).

ERIC Educational Resources Information Center

Commission on Higher Education, Philadelphia, PA. Middle States Association of Colleges and Schools.

This collection of essays from the 1999 Annual Accreditation and Quality Assurance Conference includes: "Wanted: President for the New Millennium" (Stephen Joel Trachtenberg); "Medium and Message: Passion, Values, and Quality in the New Academy" (John Daniel); "The 100th Anniversary of the College Board" (Nicholas…

The 34th Annual Fall Meeting of the American Physiological Society and the International Conference on Hydrogen Ion Transport in Epithelia.

ERIC Educational Resources Information Center

Physiologist, 1983

1983-01-01

Provided are abstracts of papers presented at the annual American Physiological Society meeting and International Conference on Hydrogen Ion Transport in Epithelia. Papers are grouped by such topic areas as lung fluid balance, renal cardiovascular integration, smooth muscle physiology, neuroendocrines (pituitary), exercise physiology, mechanics of…

Agenda of the Fourth Annual Summer Conference, NASA/USRA University Advanced Design Program

NASA Technical Reports Server (NTRS)

1988-01-01

Presentations given by the participants at the fourth annual summer conference of the NASA/USRA University Advanced Design Program are summarized. The study topics include potential space and aeronautics projects which could be undertaken during a 20 to 30 year period beginning with the Space Station Initial Operating Configuration (IOC) scheduled for the early to mid-1990's. This includes system design studies for both manned and unmanned endeavors; e.g., lunar launch and landing facilities and operations, variable artificial gravity facility for the Space Station, manned Mars aircraft and delivery system, long term space habitat, construction equipment for lunar bases, Mars oxygen production system, trans-Pacific high speed civil transport, V/STOL aircraft concepts, etc.

Proceedings of the Annual Nebraska Aviation Education Association Conference (1st, Omaha, Nebraska, January 1994). The UNO Aviation Monograph Series.

ERIC Educational Resources Information Center

Crehan, James E., Ed.

This collection of six papers constitutes the proceedings of the First Annual Conference of the Nebraska Aviation Education Association. These papers present many issues that the discipline of aviation is confronting, including those related to the aviation industry. The papers included are as follows: (1) "Using the DAT for Selection of…

Proceedings of the 18th Annual Conference on Fossil Energy Materials.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Judkins, RR

2004-11-02

The 18th Annual conference on Fossil Energy Materials was held in Knoxville, Tennessee, on June 2 through June 4, 2004. The meeting was sponsored by the U.S. Department of Energy's (DOE) Office of Fossil Energy through the Advanced Research Materials Program (ARM). The objective of the ARM Program is to conduct research and development on materials for longer-term fossil energy applications, as well as for generic needs of various fossil fuel technologies. The management of the program has been decentralized to the DOE Oak Ridge Operations Office and Oak Ridge National Laboratory (ORNL). The research is performed by staff membersmore » at ORNL and by researchers at other national laboratories, universities, and in private industry. The work is divided into the following categories: (1) structural, ceramics, (2) new alloys and coatings, (3) functional materials, and (4) technology development and transfer.« less

Selections from the ABC 2014 Annual Conference, Philadelphia, Pennsylvania: Let Favorite Assignments Ring: Sharpening Communication Tools and Self and Career Development

ERIC Educational Resources Information Center

Whalen, D. Joel; Crenshaw, Cheri; Ortiz, Lorelei A.; Vik, Gretchen N.; Meredith, Michael J.; Deambrosi, Alfredo; Luck, Susan L.; Rausch, Georgi; Canas, Kathryn; Hicks, Nancy; Newman, Amy; Hofacker, Cynthia M.; Webb, Susan Hall; Zizik, Catherine H.

2015-01-01

This article, the first of a two-part series, catalogs teaching innovations from the 2014 Association for Business Communication Annual Conference. These 12 assignments debuted during two "My Favorite Assignment" sessions. Learning experiences included job-seeking skills--résumé writing, writing job applications, sharpening interview…

National Association for Physical Education in Higher Education Annual Conference Proceedings (San Diego, CA, January 8-10, 1982). Volume III.

ERIC Educational Resources Information Center

Gedvilas, Leo L., Ed.; And Others

This book contains 26 papers delivered at the National Association for Physical Education in Higher Education (NAPEHE) Annual Conference (1982). Section 1, "NAPEHE's Image," contains two papers, one by Don Hellison, the other by Celeste Ulrich. "The Splintering of Physical Education" is the topic of the next section, and it contains papers by…

Stanford Occasional Papers in Linguistics, No. 3. Papers from the Annual California Linguistics Conference (3rd, May 5-6, 1973).

ERIC Educational Resources Information Center

Gee, James Paul, Ed.; And Others

This volume includes 12 of the 24 papers presented at the Third Annual California Linguistics Conference. Selections are drawn from each of the four sessions, covering semantic and lexical structure, phonology, syntax, and language in context. Each of the papers includes a bibliography, as well as diagrams, charts, and appendixes when necessary.…

Schools without Fear. Proceedings of the Annual International Alliance for Invitational Education Conference (14th). International Alliance for Invitational Education.

ERIC Educational Resources Information Center

Francis, Adrianna Hayes, Ed.

Papers presented at the fourteenth Annual Conference of the Alliance for Invitational Education are (1) "Caring, Sharing, Daring: Three Tests to Help Develop More Inviting Policies, Programmes, and Procedures" (M. Ayers); (2) "Project: Gentlemen on the Move - Combating the Poor Academic and Social Performance of African American Male Youth" (D. F.…

Conference Support, 23rd Western Photosynthesis Conference 2014, Final Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wachter, Rebekka

The Western Photosynthesis Conference is a regional conference that is held on an annual basis to bring together researchers primarily from the Western United States to share their newest research advances on photosynthetic processes. The 23rd conference was focused on both fundamental and more applied research on the biological conversion of solar energy to various energy storage forms. Several particular areas of solar energy conversion were emphasized in this conference (see below). Some of these topics, such as carbon limitations on photosynthesis, biomimicry and phenotyping, have traditionally not been incorporated extensively in the Western Photosynthesis Conference. We found that thesemore » topics have substantially broadened of the scope of this meeting.« less

Ex-vivo absorption study of lysine R-lipoate salt, a new pharmaceutical form of R-ALA.

PubMed

Amenta, Francesco; Buccioni, Michela; Ben, Diego Dal; Lambertucci, Catia; Navia, Aleix Martí; Ngouadjeu Ngnintedem, Michael A; Ricciutelli, Massimo; Spinaci, Andrea; Volpini, Rosaria; Marucci, Gabriella

2018-06-15

Alpha-lipoic acid (ALA) oral supplements were used in many pathologies associated with increased oxidative stress. Although only R-ALA is considered the biologically active form, R,S-ALA is used in therapeutic applications even showing poor water solubility. The aim of this work was to study the absorption and transport mechanism across the intestinal barrier of new R-ALA stable and water soluble form, consisting in the lysine R-ALA salt, in presence and absence of specific inhibitors of Na + /multivitamin (SMVT) and monocarboxylic acids (MCT). The absorption of a new ALA form was investigated at rat everted sacs in comparison with R-ALA, S-ALA, and R,S-ALA. Results showed that duodenum is the best portion of intestine for ALA forms absorption. The absorption percentage of R-ALA, S-ALA, R,S-ALA, and lysine R-ALA salt was 66%, 43%, 55%, and 70%, respectively. The modest effect of the SMVT inhibitor biotin demonstrated that this transporter system is not principally involved in the absorption of lysine R-lipoate salt across the rat intestinal barrier. On the contrary, the MCT inhibitor octanoic acid significantly reduced the transport of this salt, whit an absorption decrease of R-ALA and lysine R-lipoate salt of 28% and 24%, respectively. Since the highest concentration of these inhibitors did not completely inhibit the absorption of lysine R-lipoate salt, other transport mechanisms probably operate for its intracellular delivery. The new form of ALA, lysine R-lipoate salt, was the most absorbed respect to the other ALA forms demonstrating that this compound is more suitable for oral administration. This new salt could represent a promising candidate for ALA oral supplementation. Copyright © 2018 Elsevier B.V. All rights reserved.

Guidance and control, 1993; Annual Rocky Mountain Guidance and Control Conference, 16th, Keystone, CO, Feb. 6-10, 1993

NASA Technical Reports Server (NTRS)

Culp, Robert D. (Editor); Bickley, George (Editor)

1993-01-01

Papers from the sixteenth annual American Astronautical Society Rocky Mountain Guidance and Control Conference are presented. The topics covered include the following: advances in guidance, navigation, and control; control system videos; guidance, navigation and control embedded flight control systems; recent experiences; guidance and control storyboard displays; and applications of modern control, featuring the Hubble Space Telescope (HST) performance enhancement study.

Paediatric conference.

PubMed

1999-04-01

The venue for the postponed RCN Children in A&E (Within the RCN A&E Nursing Association) Annual Conference, Saturday, April 24 1999 will be The Education Centre, Birmingham Children's Hospital, Steelhouse Lane, Birmingham.

Identification of current priorities for research in humanitarian action: proceedings of the First Annual UN OCHA Policy and Research Conference.

PubMed

Foran, Mark P; Greenough, Paul G; Thow, Andrew; Gilman, Daniel; Schütz, Andreas; Chandran, Rahul; Baiocchi, Allegra

2012-06-01

On December 12-13, 2011, the United Nations Office for the Coordination of Humanitarian Affairs (OCHA) hosted a humanitarian policy and research conference on the theme of "Risk, Adaptation and Innovation in Humanitarian Action." The four sessions of the conference covered humanitarian action in a changing world, adaptation and innovation in humanitarian action, humanitarian action in protracted and violent conflict, and effective humanitarian action. This special report contains summaries of presentations in each session and the conclusions resulting from the discussions throughout. Through a process of open discussion, debate, and a closing survey, the conference participants identified four top priorities in humanitarian research for the coming years: evidence-driven humanitarian decision-making; accountability and transparency; risk and agility; and partnership. In addition to plans for a 2nd Annual Research and Policy conference in December of 2012, specific outcomes of the conference include a series of regional workshops in 2012 and 2013, launching with Asia, Africa and the Middle East; creation of Policy Working Groups (PWG) for each research priority identified; and a new flagship OCHA publication, to be launched in late 2012 or early 2013, which will share the progress made on the research priorities identified.

Evaluation of ALA-induced PpIX as a photosensitizer for PDT in cats

NASA Astrophysics Data System (ADS)

Lucroy, Michael D.; Edwards, Benjamin F.; Peavy, George M.; Krasieva, Tatiana B.; Griffey, Stephen M.; Madewell, Bruce R.

1998-07-01

Given exogenously, ALA defeats intrinsic regulatory feedback mechanisms allowing intracellular accumulation of protoporphyrin IX (PpIX), a highly efficient photosensitizer. In vivo, PpIX synthesis in neoplastic mammary tissues averages 20-fold higher than in normal mammary tissues. PpIX is retained intracellularly, unlike perivascular localization of other photosensitizers, and it is then cleared quickly from the body. In vitro, ALA induced PpIX production in our laboratory in 6 cell lines tested, including an established feline kidney cell line and dermal fibroblasts from primary skin biopsy explant, resulting in photosensitization. Fluorescent microscopy confirmed PpIX production in skin adnexae following ALA administration in a normal cat. To evaluate toxicity, three cats were treated with a single i.v. dose of ALA (either 100, 200, of 400 mg/kg) and followed for 7 days. Cats receiving 100 or 200 mg/kg ALA i.v. had elevated liver enzymes and bilirubin within 24 hours. Histopathology revealed hydropic changes in the liver and renal fibrosis. The cat receiving 400 mg/kg ALA intravenously had cutaneous flush, bradycardia and apnea associated with ALA administration; within 24 hours the cat was lethargic, anorectic and icteric. ALT, AST and bilirubin concentrations had increased significantly. At necropsy the liver had a prominent lobular pattern; histopathology revealed severe periportal hepatitis and splenic necrosis. Systemically administered ALA induces PpIX production, but toxicity may preclude its clinical application in the cat. PpIX levels seem to be more time dependent than those dependent at these three ALA doses and they are well beyond the saturation point for adequate PpIX conversion. The literature is scant regarding toxicity associated with parenteral administration of ALA.

Conference for Undergraduate Women in Physics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bonnie Fleming

2009-04-01

The Yale Conference for Undergraduate Women in Physics was held on January 18th and 19th, 2008. The conference, targeted toward undergraduates in the Northeast, was a huge success. It was well attended by both a slate of impressive speakers including Janet Conrad, Mildred Dresselhaus, Elsa Garmire, Howard Georgi, Liz Rhodes, Meg Urry and Wendy Zhang, and many interested attendees. Talks were on current research, about issues for women in physics, and on the application process for graduate school. There was also a career panel, student talks, and a student poster session. The conference ran concurrently with the third annual conferencemore » at USC, as well as a first annual conference at the University of Michigan. Our purpose in creating this conference was to provide a supportive atmosphere for young physicists to connect with peers and with successful women in the field. We hope that from this conference, attendees have become confident and knowledgeable about applying to graduate school and be further inspired to pursue a career in physics. The following describes the conference program, participation and impact, logistics of running the conference and plans for the future.« less

Children in Divorced Family Systems: New Approaches. Presentations at NCCR's Annual Conference (4th, Arlington, Virginia, October 13-15, 1989).

ERIC Educational Resources Information Center

National Council for Children's Rights, Washington, DC.

The National Council for Children's Rights (NCCR) is a child-advocacy group that works to assure a child the right to two parents. This proceedings contains three presentations from the NCCR's fourth annual conference and highlights of the remaining presentations. The proceedings include: (1) a welcoming address by NCCR President David L. Levy,…

Proceedings of the RESNA 2000 Annual Conference: Technology for the New Millennium (Orlando, Florida, June 28-July 2, 2000). Volume 20.

ERIC Educational Resources Information Center

Winters, Jack, Ed.

This text contains papers presented at the annual conference of the Rehabilitation Engineering and Assistive Technology Society of North America (RESNA) held on June 28-July 2, 2000, in Orlando, Florida. Papers are divided into the following sections: (1) technology for special populations, which includes papers that discuss using…

In vivo study of ALA PLGA nanoparticles-mediated PDT for treating cutaneous squamous cell carcinoma

NASA Astrophysics Data System (ADS)

Wang, Xiaojie; Shi, Lei; Huang, Zheng; Wang, Xiuli

2014-09-01

Background: Squamous cell carcinoma (SCC) is a common skin cancer and its treatment is still a challenge. Although topical photodynamic therapy (PDT) is effective for treating in situ and superficial SCC, the effectiveness of topical ALA delivery to thick SCC can be limited by its bioavailability. Polylactic-co-glycolic acid nanopartieles (PLGA NPs) might provide a promising ALA delivery strategy. The aim of this study was to evaluate the efficacy of ALA PLGA NPs PDT for the treatment of cutaneous SCC in a mouse model. Methods: ALA loaded PLGA NPs were prepared and characterized. The therapeutic efficacy of ALA PLGA NP mediated PDT in treating UV-induced cutaneous SCC in the mice model were examined. Results: In vivo study showed that ALA PLGA NPs PDT were more effective than free ALA of the same concentration in treating mouse cutaneous SCC. Conclusion: ALA PLGA NPs provides a promising strategy for delivering ALA and treating cutaneous SCC.

GIS-based accident location and analysis system (GIS-ALAS) : project report : phase I

DOT National Transportation Integrated Search

1998-04-06

This report summarizes progress made in Phase I of the geographic information system (GIS) based Accident Location and Analysis System (GIS-ALAS). The GIS-ALAS project builds on PC-ALAS, a locationally-referenced highway crash database query system d...

Teaching of Psychology: Ideas and Innovations. Proceedings and Papers of the Annual Conference on Undergraduate Teaching of Psychology (20th, Monticello, New York, March 29-31, 2006)

ERIC Educational Resources Information Center

Oswald, Patricia A., Ed.; Zaromatidis, Katherine, Ed.; Levine, Judith R., Ed.; Indenbaum, Gene, Ed.

2006-01-01

This document includes proceedings, abstracts, and papers of the 20th Annual Conference on Undergraduate Teaching of Psychology, which was held on March 29-31, 2006 in Monticello, NY. The conference, which dealt with ideas and innovations in the teaching of psychology, was sponsored by the Psychology Department of the Farmingdale State University.…

2016 update on APBioNet's annual international conference on bioinformatics (InCoB).

PubMed

Schönbach, Christian; Verma, Chandra; Wee, Lawrence Jin Kiat; Bond, Peter John; Ranganathan, Shoba

2016-12-22

InCoB became since its inception in 2002 one of the largest annual bioinformatics conferences in the Asia-Pacific region with attendance ranging between 150 and 250 delegates depending on the venue location. InCoB 2016 in Singapore was attended by almost 220 delegates. This year, sessions on structural bioinformatics, sequence and sequencing, and next-generation sequencing fielded the highest number of oral presentation. Forty-four out 96 oral presentations were associated with an accepted manuscript in supplemental issues of BMC Bioinformatics, BMC Genomics, BMC Medical Genomics or BMC Systems Biology. Articles with a genomics focus are reviewed in this editorial. Next year's InCoB will be held in Shenzen, China from September 20 to 22, 2017.

A study of parallelism of the occlusal plane and ala-tragus line.

PubMed

Sadr, Katayoun; Sadr, Makan

2009-01-01

Orientation of the occlusal plane is one of the most important clinical procedures in prostho-dontic rehabilitation of edentulous patients. The aim of this study was to define the best posterior reference point of ala-tragus line for orientation of occlusal plane for complete denture fabrication. Fifty-three dental students (27 females and 26 males) with complete natural dentition and Angel's Class I occlusal relationship were selected. The subjects were photographed in natural head position while clenching on a Fox plane. After tracing the photographs, the angles between the following lines were measured: the occlusal plane (Fox plane) and the superior border of ala-tragus, the occlusal plane (Fox plane) and the middle of ala-tragus as well as the occlusal plane (Fox plane) and the inferior border of ala-tragus. Descriptive statistics, one sample t-test and independent t-test were used. P value less than 0.05 was considered significant. There was no parallelism between the occlusal plane and ala-tragus line with three different posterior ends and one sample t-test showed that the angles between them were significantly different from zero (p<0.05). However, the supe-rior border of ala-tragus line had the lowest mean angle, 1.80° (3.12) and was almost parallel to the occlusal plane. The superior border of the tragus is suggested as the posterior reference for ala-tragus line.

Increasing Understanding of Public Problems and Policies: 1993. [Proceedings of the Annual Conference of the National Public Policy Education Committee (43rd, Clearwater Beach, Florida, September 12-15, 1993).

ERIC Educational Resources Information Center

Halbrook, Steve A., Ed.; Grace, Teddee E., Ed.

The annual conference of the National Public Policy Education Committee (NPPEC) is held to improve the policy education efforts of extension workers responsible for public affairs programs. This publication contains 26 conference papers: "Rural America and the Information Revolution: An Exploration of Possibilities and Potentialities"…

IFLA Council and General Conference: Conference Programme and Proceedings (65th, Bangkok, Thailand, August 20-28, 1999).

ERIC Educational Resources Information Center

International Federation of Library Associations and Institutions, The Hague (Netherlands).

This proceedings of the 1999 IFLA (International Federation of Library Associations and Institutions) annual conference contains: information on the current, future, and past conferences; a message from H.R.H. Princess Maha Chakri Sirindhorn, the patron of the Thai Library Association; a conference program; an alphabetical list of authors; and 112…

Second annual Transportation Infrastructure Engineering Conference.

DOT National Transportation Integrated Search

2013-10-01

The conference will highlight a few of the current projects that have been sponsored by the Center for Transportation : Infrastructure and Safety (CTIS), a national University Transportation Center at S&T. In operation since 1998, the CTIS supports :...

The Benefits of Attending the Annual Biomedical Research Conference for Minority Students (ABRCMS): The Role of Research Confidence

PubMed Central

Casad, Bettina J.; Chang, Amy L.; Pribbenow, Christine M.

2016-01-01

The Annual Biomedical Research Conference for Minority Students (ABRCMS) is designed to support undergraduate students’ professional development as future scientists. Juniors, seniors, and postbaccalaureates who attended ABRCMS during 2008–2011 were emailed a link to an online questionnaire in which they reported their experiences at the conference. Attendees reported many ABRCMS-provided benefits. Frequency of attending or presenting at ABRCMS is positively related to science self-efficacy, research confidence, sense of belonging in science, and intentions to pursue a research degree in graduate school. Increased research confidence predicts graduate school plans and intentions for a research career in science; however, men were slightly more likely to intend to pursue a research career than women, likely due to higher research confidence. Although all attendees benefited from ABRCMS, underrepresented minority (URM) students had higher science self-efficacy and sense of belonging in science after attending ABRCMS than non-URM students. This finding demonstrates the effectiveness of ABRCMS as an intervention to increase the representation and success of URMs in science. Results highlight the importance of attending a minority-oriented research conference where URMs can develop their science self-efficacy, research confidence, and sense of belonging in science. However, changes to the conference and undergraduate research experiences may be necessary to reduce gender gaps. PMID:27562962

6th Annual Midwest Conference for Undergraduate Women in Physics, January 18-20, 2013, Urbana, Illinois

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pitts, Kevin T.

This document is the program for the 6th Annual Midwest Conference for Undergraduate Women in Physics, which was held at the University of Illinois at Urbana-Champaign on January 18-20, 2013. The goals of the conference were to foster a culture in which undergraduate women are encouraged and supported to pursue, and also to succeed in, higher education in physics; to provide career information to students in physics and related fields; to give women the resources, motivation, and confidence to apply to graduate school and successfully complete a Ph.D. program in Physics; to provide information and dispel misconceptions about the applicationmore » process for graduate school and the diverse employment opportunities in physics and related fields, enabling women to make more informed decisions about their goals and attain them; and to connect female physics students with successful female physicists to whom they can relate and who can act as inspirational role models and mentors.« less

Proceedings of the Annual Gravity Gradiometer Conference (17th) Held in Hanscom AFB, Massachusetts on 12-13 October 1989

DTIC Science & Technology

1990-03-28

D’IC FILE COpY G---90-0067 ENVIRONMENTAL RESEARCH PAPERS , NO. 1059 AD-A223 568 PROCEEDINGS OF THE SEVENTEENTH ANNUAL GRAVITY GRADIOICET CONFERENCE 12...AVAILABILITY STATEMENT 12b. DISTRIBUTION CODE Approved for Public Release; Distribution Unlimited 13. ABSTRACT (Maximu&m 200 words)/ Fourteen papers were...instrumentation * and applications. The technical papers covered test program results, applications to gravity field mapping, gravity signal processing

Energy and environmental policy in a period of transition. Proceedings of the twenty-third annual Illinois energy conference

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-12-31

The Twenty-Third Annual Illinois Energy Conference entitled, ``Energy and Environmental Policy in a Period of Transition`` was held in Chicago, Illinois on November 20--21, 1995. The conference program explored how federal policy in energy and environment is changing and how these shifts will impact the economy of the Midwest. The conference was divided in four plenary sessions. Session 1 focused on the national policy scene where speakers discussed proposed legislation to change federal energy and environmental policy. Session 2 looked at the future structure of the energy industry, projecting the roles of natural gas, the electric utility industry, and independentmore » power producers in the overall energy system of the 21st century. Session 3 examined current federal policy in research and development as a baseline for discussing the future role of government and industry in supporting research and development. In particular, it looked at the relationship between energy research and development and global competitiveness. Finally, Session 4 attempted to tie these issues together and consider the impact of national policy change on Illinois and the Midwest.« less

Oral Language and Reading; Proceedings of the Annual Reading Conference of the Department of Elementary Education at Indiana State University (3rd, Terre Haute, June 14-15, 1973).

ERIC Educational Resources Information Center

Waterman, David C., Ed.; Gibbs, Vanita M., Ed.

This pamphlet is a collection of the speeches given at the Third Annual Reading Conference at Indiana State University, Terre Haute. The theme of the conference was "Oral Language and Reading." The contents include: "Official Program"; opening remarks, "They Led and Followed," by William G. McCarthy; opening address, "Strategies for Reading…

Sustaining the Vision. Selected Papers from the Annual Conference of the International Association of School Librarianship (24th, Worcester, England, July 17-21, 1995).

ERIC Educational Resources Information Center

International Association of School Librarianship, Seattle, WA.

Themes of the 24th Annual International Association of School Librarianship conference included: "School Librarianship"; "Children's Literature"; "Technology"; and "Children's Literature, Literacy, and School Librarianship." The following presented papers are assembled in this proceedings: (1) "For…

Proceedings of the Annual Conference of the International Group for the Psychology of Mathematics Education with the North American Chapter 12th PME-NA Conference (14th, Mexico, July 15-20, 1990), Volume 1.

ERIC Educational Resources Information Center

Booker, George, Ed.; Cobb, Paul, Ed.; de Mendicuti, Teresa N., Ed.

This proceedings of the annual conference of the International Group for the Psychology of Mathematics Education (PME) includes the following papers: "The Knowledge of Cats: Epistemological Foundations of Mathematics Education" (R.B. Davis) and "PME Algebra Research: A Working Perspective" (E. Filloy); "Some Misconceptions in Calculus: Anecdotes…

SELECTED PAPERS FROM PROFESSIONAL PROGRAM SEGMENTS OF UNITED CEREBRAL PALSY'S ANNUAL CONFERENCE (15TH, LOS ANGELES, CALIFORNIA, MARCH 11-13, 1965).

ERIC Educational Resources Information Center

United Cerebral Palsy Association, New York, NY.

THIS PUBLICATION PRESENTS SELECTED PAPERS FROM THE UNITED CEREBRAL PALSY ASSOCIATION'S 15TH ANNUAL CONFERENCE, MARCH 13, 1965. PAPERS ARE--(1) "S IS TO TURN" BY PAUL V. CARLSON, (2) "CERTAIN ASPECTS OF THE FUNCTIONAL STATUS OF THE FETUS IN UTERO" BY FORREST H. ADAMS, (3) "ENCEPHALITIS--COMMON CAUSES AND AFTER EFFECTS"…

Business of biosimilars - 14th annual conference (October 15-17, 2013 - Boston, Massachusetts, USA).

PubMed

Bourgoin, A

2013-12-01

Competition in the biological market offers a new set of opportunities and challenges within the healthcare industry. Biosimilars, like generic small-molecule drugs, can provide cost savings and increase patient access, while also promoting innovation. While large molecule manufacturers face many challenges unique to complex therapeutics, it is becoming clear that the commercialization of biosimilars shares many of the same hurdles as the generics market. The 14th Annual Business of Biosimilars Conference provided quality presentations from industry leaders regarding many commercial considerations for stakeholders interested in entering the biosimilars market. Opportunities to network with industry experts were offered, with over 120 attendees. Copyright 2013 Prous Science, S.A.U. or its licensors. All rights reserved.

A Study of Parallelism of the Occlusal Plane and Ala-Tragus Line

PubMed Central

Sadr, Katayoun; Sadr, Makan

2009-01-01

Background and aims Orientation of the occlusal plane is one of the most important clinical procedures in prostho-dontic rehabilitation of edentulous patients. The aim of this study was to define the best posterior reference point of ala-tragus line for orientation of occlusal plane for complete denture fabrication. Materials and methods Fifty-three dental students (27 females and 26 males) with complete natural dentition and Angel’s Class I occlusal relationship were selected. The subjects were photographed in natural head position while clenching on a Fox plane. After tracing the photographs, the angles between the following lines were measured: the occlusal plane (Fox plane) and the superior border of ala-tragus, the occlusal plane (Fox plane) and the middle of ala-tragus as well as the occlusal plane (Fox plane) and the inferior border of ala-tragus. Descriptive statistics, one sample t-test and independent t-test were used. P value less than 0.05 was considered significant. Results There was no parallelism between the occlusal plane and ala-tragus line with three different posterior ends and one sample t-test showed that the angles between them were significantly different from zero (p<0.05). However, the supe-rior border of ala-tragus line had the lowest mean angle, 1.80° (3.12) and was almost parallel to the occlusal plane. Conclusion The superior border of the tragus is suggested as the posterior reference for ala-tragus line. PMID:23230496

Proceedings of the Annual Conference of the International Group for the Psychology of Mathematics Education with the North American Chapter 12th PME-NA Conference (14th, Mexico, July 15-20, 1990), Volume 2.

ERIC Educational Resources Information Center

Booker, George, Ed.; Cobb, Paul, Ed.; de Mendicuti, Teresa N., Ed.

This proceedings of the annual conference of the International Group for the Psychology of Mathematics Education (PME) includes the following research papers: "Children's Connections among Representations of Mathematical Ideas" (A. Alston & C.A. Maher); "Algebraic Syntax Errors: A Study with Secondary School Children" (A. Avila, F. Garcia, & T.…

Proceedings of the Annual Conference of the International Group for the Psychology of Mathematics Education with the North American Chapter 12th PME-NA Conference (14th, Mexico, July 15-20, 1990), Volume 3.

ERIC Educational Resources Information Center

Booker, George, Ed.; Cobb, Paul, Ed.; de Mendicuti, Teresa N.

This proceedings of the annual conference of the International Group for the Psychology of Mathematics Education (PME) contains the following research papers: "The Construct Theory of Rational Numbers: Toward a Semantic Analysis" (M. Behr & G. Harel); "Reflections on Dealing: An Analysis of One Child's Interpretations" (G. Davis); "About…

Substitution of the Lys Linker with the β-Ala Linker Dramatically Decreased the Renal Uptake of 99mTc-Labeled Arg-X-Asp-Conjugated and X-Ala-Asp-Conjugated α-Melanocyte Stimulating Hormone Peptides

PubMed Central

2015-01-01

The purpose of this study was to examine whether the substitution of the Lys linker with the β-Ala could reduce the renal uptake of 99mTc-labeled Arg-X-Asp-conjugated and X-Ala-Asp-conjugated α-melanocyte stimulating hormone (α-MSH) peptides. RSD-β-Ala-(Arg11)CCMSH (1) {c[Arg-Ser-Asp-dTyr-Asp]-β-Ala-Cys-Cys-Glu-His-dPhe-Arg-Trp-Cys-Arg-Pro-Val-NH2}, RTD-β-Ala-(Arg11)CCMSH (2), RVD-β-Ala-(Arg11)CCMSH (3), RAD-β-Ala-(Arg11)CCMSH (4), NAD-β-Ala-(Arg11)CCMSH (5), and EAD-β-Ala-(Arg11)CCMSH (6) peptides were synthesized and evaluated for their melanocortin 1 (MC1) receptor binding affinities in B16/F1 melanoma cells. The biodistribution of their 99mTc-conjugates were determined in B16/F1 melanoma-bearing C57 mice. The substitution of the Lys linker with β-Ala linker dramatically reduced the renal uptake of all six 99mTc-peptides. 99mTc-4 exhibited the highest melanoma uptake (15.66 ± 6.19% ID/g) and the lowest kidney uptake (20.18 ± 3.86% ID/g) among these 99mTc-peptides at 2 h postinjection. The B16/F1 melanoma lesions could be clearly visualized by single photon emission computed tomography (SPECT)/CT using 99mTc-4 as an imaging probe. PMID:25290883

Substitution of the Lys linker with the β-Ala linker dramatically decreased the renal uptake of 99mTc-labeled Arg-X-Asp-conjugated and X-Ala-Asp-conjugated α-melanocyte stimulating hormone peptides.

PubMed

Flook, Adam M; Yang, Jianquan; Miao, Yubin

2014-11-13

The purpose of this study was to examine whether the substitution of the Lys linker with the β-Ala could reduce the renal uptake of (99m)Tc-labeled Arg-X-Asp-conjugated and X-Ala-Asp-conjugated α-melanocyte stimulating hormone (α-MSH) peptides. RSD-β-Ala-(Arg(11))CCMSH (1) {c[Arg-Ser-Asp-dTyr-Asp]-β-Ala-Cys-Cys-Glu-His-dPhe-Arg-Trp-Cys-Arg-Pro-Val-NH2}, RTD-β-Ala-(Arg(11))CCMSH (2), RVD-β-Ala-(Arg(11))CCMSH (3), RAD-β-Ala-(Arg(11))CCMSH (4), NAD-β-Ala-(Arg(11))CCMSH (5), and EAD-β-Ala-(Arg(11))CCMSH (6) peptides were synthesized and evaluated for their melanocortin 1 (MC1) receptor binding affinities in B16/F1 melanoma cells. The biodistribution of their (99m)Tc-conjugates were determined in B16/F1 melanoma-bearing C57 mice. The substitution of the Lys linker with β-Ala linker dramatically reduced the renal uptake of all six (99m)Tc-peptides. (99m)Tc-4 exhibited the highest melanoma uptake (15.66 ± 6.19% ID/g) and the lowest kidney uptake (20.18 ± 3.86% ID/g) among these (99m)Tc-peptides at 2 h postinjection. The B16/F1 melanoma lesions could be clearly visualized by single photon emission computed tomography (SPECT)/CT using (99m)Tc-4 as an imaging probe.

Proceedings of the Seventh Annual Summer Conference. NASA/USRA: University Advanced Design Program

NASA Technical Reports Server (NTRS)

1991-01-01

The Advanced Design Program (ADP) is a unique program that brings together students and faculty from U.S. engineering schools with engineers from the NASA centers through integration of current and future NASA space and aeronautics projects into university engineering design curriculum. The Advanced Space Design Program study topics cover a broad range of projects that could be undertaken during a 20-30 year period beginning with the deployment of the Space Station Freedom. The Advanced Aeronautics Design Program study topics typically focus on nearer-term projects of interest to NASA, covering from small, slow-speed vehicles through large, supersonic passenger transports and on through hypersonic research vehicles. Student work accomplished during the 1990-91 academic year and reported at the 7th Annual Summer Conference is presented.

ALA-induced PpIX fluorescence in epileptogenic tissue

NASA Astrophysics Data System (ADS)

Kleen, Jonathan K.; Valdes, Pablo A.; Harris, Brent T.; Holmes, Gregory L.; Paulsen, Keith D.; Roberts, David W.

2011-03-01

Astrogliotic tissue displays markedly increased levels of ALA-induced PpIX fluorescence, making it useful for fluorescence-guided resection in glioma surgery. In patients with temporal lobe epilepsy (TLE) and corresponding animal models, there are areas of astrogliosis that often co-localize with the epileptic focus, which can be resected to eliminate seizures in the majority of treated patients. If this epileptogenic tissue can exhibit PpIX fluorescence that is sufficiently localized, it could potentially help identify margins in epilepsy surgery. We tested the hypothesis that ALA-induced PpIX fluorescence could visually accentuate epileptogenic tissue, using an established animal model of chronic TLE. An acute dose of pilocarpine was used to induce chronic seizure activity in a rat. This rat and a normal control were given ALA, euthanized, and brains examined post-mortem for PpIX fluorescence and neuropathology. Preliminary evidence indicates increased PpIX fluorescence in areas associated with chronic epileptic changes and seizure generation in TLE, including the hippocampus and parahippocampal areas. In addition, strong PpIX fluorescence was clearly observed in layer II of the piriform cortex, a region known for epileptic reorganization and involvement in the generation of seizures in animal studies. We are further investigating whether ALA-induced PpIX fluorescence can consistently identify epileptogenic zones, which could warrant the extension of this technique to clinical studies for use as an adjuvant guidance technology in the resection of epileptic tissue.

Guidance and control, 1993; Annual Rocky Mountain Guidance and Control Conference, 16th, Keystone, CO, Feb. 6-10, 1993

NASA Astrophysics Data System (ADS)

Culp, Robert D.; Bickley, George

Papers from the sixteenth annual American Astronautical Society Rocky Mountain Guidance and Control Conference are presented. The topics covered include the following: advances in guidance, navigation, and control; control system videos; guidance, navigation and control embedded flight control systems; recent experiences; guidance and control storyboard displays; and applications of modern control, featuring the Hubble Space Telescope (HST) performance enhancement study. For individual titles, see A95-80390 through A95-80436.

Selections from the ABC 2016 Annual Conference, Albuquerque, New Mexico: Bright as Stars in the Albuquerque Desert Sky: Classroom-Tested Business Communication Assignments

ERIC Educational Resources Information Center

Whalen, D. Joel, Ed.

2017-01-01

This article, the first of a two-part series, presents 13 teaching innovations debuted at the 2016 Association for Business Communication's annual conference. The second edition of "My Favorite Assignment" will be published in the fall 2017 "Business and Professional Communication Quarterly". Assignments include international…

Gender Diversity in a STEM Subfield - Analysis of a Large Scientific Society and Its Annual Conferences.

PubMed

Shishkova, Evgenia; Kwiecien, Nicholas W; Hebert, Alexander S; Westphall, Michael S; Prenni, Jessica E; Coon, Joshua J

2017-12-01

Speaking engagements, serving as session chairs, and receiving awards at national meetings are essential stepping stones towards professional success for scientific researchers. Studies of gender parity in meetings of national scientific societies repeatedly uncover bias in speaker selection, engendering underrepresentation of women among featured presenters. To continue this dialogue, we analyzed membership data and annual conference programs of a large scientific society (>7000 members annually) in a male-rich (~70% males), technology-oriented STEM subfield. We detected a pronounced skew towards males among invited keynote lecturers, plenary speakers, and recipients of the society's Senior Investigator award (15%, 13%, and 8% females, respectively). However, the proportion of females among Mid-Career and Young Investigator award recipients and oral session chairs resembled the current gender distribution of the general membership. Female members were more likely to present at the conferences and equally likely to apply and be accepted for oral presentations as their male counterparts. The gender of a session chair had no effect on the gender distribution of selected applicants. Interestingly, we identified several research subareas that were naturally enriched (i.e., not influenced by unequal selection of presenters) for either female or male participants, illustrating within a single subfield the gender divide along biology-technology line typical of all STEM disciplines. Two female-enriched topics experienced a rapid growth in popularity within the examined period, more than doubling the number of associated researchers. Collectively, these findings contribute to the contemporary discourse on gender in science and hopefully will propel positive changes within this and other societies. Graphical abstract ᅟ.

Gender Diversity in a STEM Subfield - Analysis of a Large Scientific Society and Its Annual Conferences

NASA Astrophysics Data System (ADS)

Shishkova, Evgenia; Kwiecien, Nicholas W.; Hebert, Alexander S.; Westphall, Michael S.; Prenni, Jessica E.; Coon, Joshua J.

2017-12-01

Speaking engagements, serving as session chairs, and receiving awards at national meetings are essential stepping stones towards professional success for scientific researchers. Studies of gender parity in meetings of national scientific societies repeatedly uncover bias in speaker selection, engendering underrepresentation of women among featured presenters. To continue this dialogue, we analyzed membership data and annual conference programs of a large scientific society (>7000 members annually) in a male-rich ( 70% males), technology-oriented STEM subfield. We detected a pronounced skew towards males among invited keynote lecturers, plenary speakers, and recipients of the society's Senior Investigator award (15%, 13%, and 8% females, respectively). However, the proportion of females among Mid-Career and Young Investigator award recipients and oral session chairs resembled the current gender distribution of the general membership. Female members were more likely to present at the conferences and equally likely to apply and be accepted for oral presentations as their male counterparts. The gender of a session chair had no effect on the gender distribution of selected applicants. Interestingly, we identified several research subareas that were naturally enriched (i.e., not influenced by unequal selection of presenters) for either female or male participants, illustrating within a single subfield the gender divide along biology-technology line typical of all STEM disciplines. Two female-enriched topics experienced a rapid growth in popularity within the examined period, more than doubling the number of associated researchers. Collectively, these findings contribute to the contemporary discourse on gender in science and hopefully will propel positive changes within this and other societies. [Figure not available: see fulltext.

Sixth National Conference on Citizenship.

ERIC Educational Resources Information Center

Department of Justice, Washington, DC.

The document presents proceedings from the sixth in a series of annual national citizenship conferences. Held in Washington, D.C. in 1951, the conference served as a forum where educational, political, business, religious, labor, civic, and communications leaders could explore functions and duties of American citizenship. The theme of the…

U.S.-Africa Business Conference Summary

EPA Science Inventory

The State Department, in collaboration with several co-sponsors and other US government agencies, hosted the U.S.-Africa Business Conference in Cincinnati, Ohio, June 21-22, at the Westin Cincinnati Hotel. The conference followed the annual African Growth and Opportunity Act (AGO...

The 2016 Bioinformatics Open Source Conference (BOSC).

PubMed

Harris, Nomi L; Cock, Peter J A; Chapman, Brad; Fields, Christopher J; Hokamp, Karsten; Lapp, Hilmar; Muñoz-Torres, Monica; Wiencko, Heather

2016-01-01

Message from the ISCB: The Bioinformatics Open Source Conference (BOSC) is a yearly meeting organized by the Open Bioinformatics Foundation (OBF), a non-profit group dedicated to promoting the practice and philosophy of Open Source software development and Open Science within the biological research community. BOSC has been run since 2000 as a two-day Special Interest Group (SIG) before the annual ISMB conference. The 17th annual BOSC ( http://www.open-bio.org/wiki/BOSC_2016) took place in Orlando, Florida in July 2016. As in previous years, the conference was preceded by a two-day collaborative coding event open to the bioinformatics community. The conference brought together nearly 100 bioinformatics researchers, developers and users of open source software to interact and share ideas about standards, bioinformatics software development, and open and reproducible science.

Teaching, Learning, & Technology: The Connected Classroom. Proceedings of the Annual Mid-South Instructional Technology Conference (7th, Murfreesboro, Tennessee, April 7-9, 2002).

ERIC Educational Resources Information Center

Middle Tennessee State Univ., Murfreesboro.

This proceedings of the seventh annual Mid-South Instructional Technology Conference on Teaching, Learning, and Technology contains the following papers: "A Tale of Two Classes: Face-to-Face versus Online" (Carol Wilson); "Best Practices in Organization Highlighting 360 Degree Feedback" (Bonita Barger); "Collaborating Online To Teach Information…

Stimulation of respiratory changes in alae nasi length by chemoreceptor activation.

PubMed

Van Lunteren, E; Haxhiu, M A; Cherniack, N S

1986-03-01

Respiratory-related changes in length of the nasal dilator muscle, the alae nasi muscle, were measured using sonomicrometry in ten anesthetized (pentobarbital), tracheostomized, spontaneously breathing dogs. Piezoelectric crystals were inserted 7-25 mm apart along the direction of the alae nasi muscle fibers, and the effects of progressive hyperoxic hypercapnia and a peripheral and central chemoreceptor stimulant, nicotine (10-500 micrograms intravenously), were ascertained. The alae nasi shortened during inspiration in all animals, started to lengthen again towards the end of inspiration, returned to resting length during the first portion of expiration (Te-1), and remained at resting length for the remainder of expiration (Te-2). The amount of alae nasi inspiratory shortening was increased by occluding the airway for a single breath. Progressive hypercapnia caused progressive increases in the amount and velocity of nasal muscle inspiratory shortening during both unoccluded and occluded breaths; similar stimulatory effects on inspiratory shortening were seen following nicotine administration. Furthermore, both chemoreceptor stimulants caused a delay in the return of the muscle to its resting length during expiration, resulting in a significant increase in Te-1 relative to Te (Te-1/Te), and a greater amount of nasal muscle shortening to be present during Te-1. In some animals these agents also caused tonic shortening of the alae nasi, so that the muscle never returned to its resting length. These results suggest that inspiratory shortening of the alae nasi is inhibited by vagal inputs, but that chemoreceptor activation increases the amount of muscle shortening during both inspiration and early expiration.

Discover the Hidden Jewels in Your Library and Sharing the Wealth through Collaboration. Selected Papers from PIALA 2011, Pacific Islands Association of Libraries, Archives, and Museums Annual Conference (21st, Kosrae, Federated States of Micronesia, November 14-17, 2011)

ERIC Educational Resources Information Center

Drake, Paul B., Ed.

2012-01-01

This publication follows the tradition of publishing selected papers from Pacific Islands Association of Libraries, Archives and Museums (PIALA) annual conferences. This 21st annual conference was held in Kosrae, Federated States of Micronesia, November 14-17, 2011. The volume begins with a listing of the members of the PIALA 2011 Planning…

Pacific Visions: Finding, Selecting, and Using Resources for Your Libraries, Archives, and Museums. Selected Papers from PIALA 2009, Pacific Islands Association of Libraries, Archives, and Museums Annual Conference (19th, Pohnpei, Federated States of Micronesia, November 16-21, 2009)

ERIC Educational Resources Information Center

Drake, Paul B., Ed.

2011-01-01

This publication follows the tradition of publishing selected papers from Pacific Islands Association of Libraries, Archives and Museums (PIALA) annual conferences. This 19th annual conference was held in Pohnpei, Federated States of Micronesia, November 16-21, 2009. The volume begins with a listing of the members of the PIALA 2009 Planning…

International Perspectives on Environmental Education: Issues and Actions. Proceedings of the 1st International and 13th Annual Conference of the North American Association for Environmental Education (Banff, Alberta, Canada, October 5-9, 1984).

ERIC Educational Resources Information Center

Cox, Dorothy A., Ed.; Stapp, William B., Ed.

The proceedings of the first International Conference of the North American Association for Environmental Education (NAEE), which was also the 13th annual conference of the National Association of Environmental Education as the NAEE was formerly known, provides as complete a record as possible of the conference activities. Papers and reports are…

Treating cutaneous squamous cell carcinoma using ALA PLGA nanoparticle-mediated photodynamic therapy in a mouse model

NASA Astrophysics Data System (ADS)

Wang, Xiaojie; Shi, Lei; Tu, Qingfeng; Wang, Hongwei; Zhang, Haiyan; Wang, Peiru; Zhang, Linglin; Huang, Zheng; Wang, Xiuli; Zhao, Feng; Luan, Hansen

2015-03-01

Background: Squamous cell carcinoma (SCC) is a common skin cancer and its treatment is still difficult. The aim of this study was to evaluate the effectiveness of nanoparticle (NP)-assisted ALA delivery for topical photodynamic therapy (PDT) of cutaneous SCC. Methods: UV-induced cutaneous SCCs were established in hairless mice. ALA loaded polylactic-co-glycolic acid (PLGA) NPs were prepared and characterized. The kinetics of ALA PLGA NPs-induced protoporphyrin IX (PpIX) fluorescence in SCCs, therapeutic efficacy of ALA NP-mediated PDT, and immune responses were examined. Results: PLGA NPs could enhance PpIX production in SCC. ALA PLGA NP mediated topical PDT was more effective than free ALA of the same concentration in treating cutaneous SCC. Conclusion: PLGA NPs provide a promising strategy for delivering ALA in topical PDT of cutaneous SCC.

SLA at 100: Conference Preview

ERIC Educational Resources Information Center

Blumenstein, Lynn

2009-01-01

When School Library Association (SLA) convenes its annual conference in Washington, DC, June 14-17, 2009, the association will be celebrating its 100th birthday. This occasion allows for grand gestures--the SLA Salutes! Awards and Leadership Reception will be held in the Library of Congress's Great Hall. The conference also draws upon Washington…

Empowerment through Collaboration: Dimension 2009. Selected Proceedings of the 2009 Joint Conference of the Southern Conference on Language Teaching, the Foreign Language Association of Georgia, and the Southeastern Association for Language Learning Technology

ERIC Educational Resources Information Center

Southern Conference on Language Teaching, 2009

2009-01-01

"Dimension" is the annual volume containing the selected, refereed, edited Proceedings of each year's conference. The Southern Conference on Language Teaching (SCOLT), in collaboration with the Foreign Language Association of Georgia (FLAG) and the Southeast Association for Language Learning Technology (SEALLT), held its annual conference March…

ALA-PDT mediated DC vaccine for skin squamous cell carcinoma

NASA Astrophysics Data System (ADS)

Ji, Jie; Fan, Zhixia; Zhou, Feifan; Wang, Xiaojie; Shi, Lei; Zhang, Haiyan; Wang, Peiru; Yang, Degang; Zhang, Linglin; Wang, Xiuli; Chen, Wei R.

2015-03-01

Dendritic cell (DC) based vaccine has emerged as a promising immunotherapy for cancers. However, most DC vaccines so far have only achieved limited success in cancer treatment. Photodynamic therapy (PDT), an established cancer treatment strategy, can cause immunogenic apoptosis to induce an effective antitumor immune response. In this study, we developed a DC-based cancer vaccine using immunogenic apoptotic tumor cells induced by 5-aminolevulinic acid (ALA) mediated PDT. The maturation of DCs induced by PDT-treated apoptotic cells was evaluated. The anti-tumor immunity of ALA-PDT-DC vaccine was tested with mouse model. We observed the maturations of DCs potentiated by ALA-PDT treated tumor cells, including phenotypic maturation (upregulation of surface expression of MHC-II, DC80, and CD86), and functional maturation (enhanced capability to secret INF-Υ and IL-12). ALA-PDT-DC vaccine mediated by apoptotic cells provided protection against tumor in mice, far stronger than that of DC vaccine obtained from freeze/thaw treated tumor cells. Our results indicate that immunogenic apoptotic tumor cells can be more effective in enhancing DC-based cancer vaccine, which could improve the clinical application of PDT- DC vaccines.

The 2016 Bioinformatics Open Source Conference (BOSC)

PubMed Central

Harris, Nomi L.; Cock, Peter J.A.; Chapman, Brad; Fields, Christopher J.; Hokamp, Karsten; Lapp, Hilmar; Muñoz-Torres, Monica; Wiencko, Heather

2016-01-01

Message from the ISCB: The Bioinformatics Open Source Conference (BOSC) is a yearly meeting organized by the Open Bioinformatics Foundation (OBF), a non-profit group dedicated to promoting the practice and philosophy of Open Source software development and Open Science within the biological research community. BOSC has been run since 2000 as a two-day Special Interest Group (SIG) before the annual ISMB conference. The 17th annual BOSC ( http://www.open-bio.org/wiki/BOSC_2016) took place in Orlando, Florida in July 2016. As in previous years, the conference was preceded by a two-day collaborative coding event open to the bioinformatics community. The conference brought together nearly 100 bioinformatics researchers, developers and users of open source software to interact and share ideas about standards, bioinformatics software development, and open and reproducible science. PMID:27781083

Teaching, Learning, & Technology: The Challenge Continues. Proceedings of the Annual Mid-South Instructional Technology Conference (8th, Murfreesboro, Tennessee, March 30-April 1, 2003).

ERIC Educational Resources Information Center

Middle Tennessee State Univ., Murfreesboro.

This proceedings of the eight annual Mid-South Instructional Technology Conference: Teaching, Learning, & Technology contains the following selected presentations: "Design and Implementation of a Multimedia CD-ROM-Based Directed Study Preservice Teacher Education Course" (Timothy Morse); "Effective IT Integration in the Composition Classroom:…

Buoyant despite Downturn

ERIC Educational Resources Information Center

Berry, John N., III; Fialkoff, Francine; Fox, Bette-Lee; Hadro, Josh; Horrocks, Norman; Kuzyk, Raya; Oder, Norman

2009-01-01

Even as libraries face the economic downturn, a record-setting number of people attended the American Library Association (ALA) annual conference in Chicago, July 9-15. The tough economy, however, was felt in the number of exhibitors, which declined from the previous record set in 2007 in Washington, DC, and in anecdotal evidence that suggested…

"I Have a Dream, Too!": The American Dream in Coretta Scott King Award-Winning Books

ERIC Educational Resources Information Center

Parsons, Linda T.; Castleman, Michele

2011-01-01

The Coretta Scott King (CSK) Award, instituted in 1969 and recognized as an official award by the American Library Association (ALA) in 1982, is conferred annually to an African American author and an illustrator for their outstanding contributions to literature about the Black experience for children and young adults. A partial impetus for the…

Dining with the Director: A Unique Fellowship Gives Rare Perspective and Opportunity

ERIC Educational Resources Information Center

Weiss, Emily

2007-01-01

When the author ran into other recent graduates at the American Library Association (ALA) annual conference in New Orleans in 2006, several told her they were not happy with their jobs. After months of searching, they settled for positions in isolated rural libraries, have jobs with little responsibility, or are expected to manage their staff…

Restoration Moves

ERIC Educational Resources Information Center

Albanese, Andrew; Berry, John N., III; Blumenstein, Lynn; Datema, Jay; Fialkoff, Francine; Kenney, Brian; Miller, Rebecca; Oder, Norman; Rogers, Michael; Williams, Wilda

2006-01-01

This article describes how the 2006 American Library Association (ALA) Annual Conference in New Orleans will long symbolize the significance of libraries and librarians to a convention city--and to the community around it. As the first major convention in the Crescent City since the ravages of Hurricane Katrina ten months earlier, the conference…

Voyaging from the Past, to the Present, and into the Future: Knowing Your Heritage. Selected Papers from PIALA 2003, Pacific Islands Association of Libraries, Archives and Museums Annual Conference (13th, Pohnpei, Federated States of Micronesia, November 4-6, 2003)

ERIC Educational Resources Information Center

Drake, Paul B., Ed.

2003-01-01

This publication follows the tradition of publishing selected papers from Pacific Islands Association of Libraries, Archives and Museums (PIALA) annual conferences. This 13th annual conference was held in Pohnpei, Federated States of Micronesia, November 4-6, 2003. The volume begins with a listing of the members of the PIALA 2003 Planning &…

Selected Papers & Abstracts from the Annual International Conference of the Association for Experiential Education (32nd, Norfolk, Virginia, November 4-7, 2004)

ERIC Educational Resources Information Center

Roberts, Nina S., Ed.; Galloway, Shayne, Ed.

2005-01-01

In an effort to persist with providing members--and interested others--with the content of workshops from the 32nd Annual Conference held in Norfolk, the Association for Experiential Education (AEE) has decided to develop a hybrid publication that has materialized in two parts. Part I includes 11 papers: (1) Adventure Coaching (Doug Gray); (2)…

Application of 5-ALA for differential diagnostics of stomach diseases

NASA Astrophysics Data System (ADS)

Okhotnikova, Natalja L.; Dadvany, Sergey A.; Kuszin, Michail I.; Kharnas, Sergey S.; Zavodnov, Victor Y.; Sklyanskaya, Olga A.; Loschenov, Victor B.; Volkova, Anna I.; Agafonov, Valery V.

2001-01-01

59 patients with stomach diseases including gastric cancer or polyp, gastritis, esofagus disease were investigated. Before gastroscopy all patients were given 5-ALA in doses 5mg, 10mg and 20mg per 1kg of body weight orally. Fluorescence diagnostics which estimates concentration of ALA-induced PPIX in regular and alternated tissues of gastric mucosa were carried out in 2-4 hours. Using of 5-ALA has shown high diagnostic effectiveness for differential diagnostics of stomach diseases. This technique has proved 10 diagnosis of cancer and revealed 15 malignant stomach diseases including 4 cancer in situ for patients with preliminary diagnosis of gastric ulcer. It also revealed 5 patients with enhanced fluorescence for which aimed biopsy has shown high degree of inflammation process. The latter were assigned as a risk group.

Proceedings of the Tenth Annual National Conference on Ada Technology. Held in Arlington, VA, on February 24-28, 1992

DTIC Science & Technology

1992-02-01

Newsletter, Vol. 5, No. 1, January 1983 be translated from HAL’S. 4. Klumpp, Allan R., An Ada Linear Algebra Software development costs for using the...a linear algebra approach to As noted above, the concept of the problem and address the problem of unitdimensional analysis extends beyond problems...you will join us again next year. The 11th Annual Conference on Ada Technology (1993) will be held here at the Hyatt Regency - Crystal City

Latest results of 5-ALA-based fluorescence diagnosis and other medical disciplines

NASA Astrophysics Data System (ADS)

Baumgartner, Reinhold

1999-02-01

Preclinical and clinical studies on 5-aminolevulinic acid (5- ALA) induced Protoporphyrin IX (PPIX) are performed in various departments now following promising clinical results for the detection of bladder cancer in urology. This paper provides an overview on the progress of 5-ALA assisted fluorescence diagnosis in urology, pulmonology, neurosurgery, gynecology and ENT coordinated by the Laser Research Laboratory of the Ludwig-Maximilians-University in Munich. 5-ALA can be applied either topically or systematically to induce an intracellular accumulation of fluorescing PPIX. With appropriate dosage of 5-ALA, malignant tissue can be stained selectively, and irradiation with violet light excites a bright red fluorescence of the tumor visible with naked eyes. Optical properties of the tissue tend to hamper the precise identification and demarcation of suspect areas in fluorescence images. Multicolor remission and fluorescence imaging, therefore, should improve tumor localization in future.

Conversion of the agent-oriented domain-specific language ALAS into JavaScript

NASA Astrophysics Data System (ADS)

Sredojević, Dejan; Vidaković, Milan; Okanović, Dušan; Mitrović, Dejan; Ivanović, Mirjana

2016-06-01

This paper shows generation of JavaScript code from code written in agent-oriented domain-specific language ALAS. ALAS is an agent-oriented domain-specific language for writing software agents that are executed within XJAF middleware. Since the agents can be executed on various platforms, they must be converted into a language of the target platform. We also try to utilize existing tools and technologies to make the whole conversion process as simple as possible, as well as faster and more efficient. We use the Xtext framework that is compatible with Java to implement ALAS infrastructure - editor and code generator. Since Xtext supports Java, generation of Java code from ALAS code is straightforward. To generate a JavaScript code that will be executed within the target JavaScript XJAF implementation, Google Web Toolkit (GWT) is used.

Properties of myelin altered peptide ligand cyclo(87-99)(Ala91,Ala96)MBP87-99 render it a promising drug lead for immunotherapy of multiple sclerosis.

PubMed

Deraos, George; Rodi, Maria; Kalbacher, Hubert; Chatzantoni, Kokona; Karagiannis, Fotios; Synodinos, Loukas; Plotas, Panayiotis; Papalois, Apostolos; Dimisianos, Nikolaos; Papathanasopoulos, Panagiotis; Gatos, Dimitrios; Tselios, Theodore; Apostolopoulos, Vasso; Mouzaki, Athanasia; Matsoukas, John

2015-08-28

Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system, and it has been established that autoreactive T helper (Th) cells play a crucial role in its pathogenesis. Myelin basic protein (MBP) epitopes are major autoantigens in MS, and the sequence MBP87-99 is an immunodominant epitope. We have previously reported that MBP87-99 peptides with modifications at principal T-cell receptor (TCR) contact sites suppressed the induction of EAE symptoms in rats and SJL/J mice, diverted the immune response from Th1 to Th2 and generated antibodies that did not cross react with the native MBP protein. In this study, the linear and cyclic analogs of the MBP87-99 epitope, namely linear (Ala91,Ala96)MBP87-99 (P2) and cyclo(87-99)(Ala91,Ala96)MBP87-99 (P3), were evaluated for their binding to HLA-DR4, stability to lysosomal enzymes, their effect on cytokine secretion by peripheral blood mononuclear cells (PBMC) derived from MS patients or healthy subjects (controls), and their effect in rat EAE. P1 peptide (wild-type, MBP87-99) was used as control. P2 and P3 did not alter significantly the cytokine secretion by control PBMC, in contrast to P1 that induced moderate IL-10 production. In MS PBMC, P2 and P3 induced the production of IL-2 and IFN-γ, with a simultaneous decrease of IL-10, whereas P1 caused a reduction of IL-10 secretion only. The cellular response to P3 indicated that cyclization did not affect the critical TCR contact sites in MS PBMC. Interestingly, the cyclic P3 analog was found to be a stronger binder to HLA-DR4 compared to linear P2. Moreover, cyclic P3 was more stable to proteolysis compared to linear P2. Finally, both P2 and P3 suppressed EAE induced by an encephalitogenic guinea pig MBP74-85 epitope in Lewis rats whereas P1 failed to do so. In conclusion, cyclization of myelin altered peptide ligand (Ala91,Ala96)MBP87-99 improved binding affinity to HLA-DR4, resistance to proteolysis and antigen-specific immunomodulation

International Federation of Library Associations Annual Conference Papers. Bibliographic Control Division: Bibliography and Cataloguing Sections (47th, Leipzig, East Germany, August 17-22, 1981).

ERIC Educational Resources Information Center

Vita, Susan H.; And Others

This set of papers delivered to the Bibliographic Control Division of the International Federation of Library Associations (IFLA) during its 47th annual conference (1981) includes: "Cataloging in Publication in the United States--Problems and Prospects," by Susan H. Vita; "Development and Coordination of Bibliographic Activities:…

Non-Traditional and Interdisciplinary Programs. Selected Papers from the Annual Conference on Non-Traditional & Interdisciplinary Programs (2nd, Arlington, Virginia, June 27-29, 1984).

ERIC Educational Resources Information Center

Fonseca, James W., Comp.

A total of 47 papers are presented from the George Mason University (Virginia) second annual conference on nontraditional, interdisciplinary, and external degree programs. Among the papers are authors are: "A Learning Theory Account of Walden University's Doctoral Instructional Program" (B. M. Austin); "Hospital Based Interdisciplinary Education…

The Conference Facilitator Model: Improving the Value of Conference Attendance for Attendees and the Organization.

PubMed

Nebrig, Dawn; Munafo, Jennifer; Goddard, Julie; Tierney, Carol

2015-09-01

Healthcare leaders face a multitude of priorities demanding their attention and resources, from patient, employee safety and hospital-acquired conditions to predicting future revenue in the context of healthcare reform. Assessing value requires balancing outcomes and experience with cost. How does allocating funds for professional nursing conferences measure up? What is a valid return on investment when we send staff nurses to professional conferences, specifically the annual Magnet® conference? The following article describes how Cincinnati Children's Hospital Medical Center answered these questions and redefined the expectations for conference attendees while enhancing the experience and the reportable outcomes for practice and the organization.

From Practice to Profession. Dimension 2007. Selected Proceedings of the 2007 Joint Conference of the Southern Conference on Language Teaching, the Foreign Language Association of Georgia, and the Southeastern Association for Language Laboratory Technology

ERIC Educational Resources Information Center

Van Houton, Jacque Bott; Gascoigne, Carolyn; Arnold, Nike; Johnson, Catherine T.; Thomas, Patricia; Fountain, Anne; Fountain, Catherine; Cheatham, Rosalie M.; Sanatullov, Marat; Sanatullova-Allison, Elvira; Cherry, C. Maurice, Ed.; Bradley, Lee, Ed.

2007-01-01

"Dimension" is the annual volume containing the selected, refereed, edited Proceedings of each year's conference. "From Practice to Profession" was the announced theme of the annual conference of the Southern Conference on Language Teaching (SCOLT), held March 1-3, 2007, at the Atlanta (GA) Renaissance Hotel, in partnership…

Non-Traditional and Interdisciplinary Programs. Selected Papers from the Annual Conference on Non-Traditional and Interdisciplinary Programs (3rd, Arlington, Virginia, July 1-3, 1985).

ERIC Educational Resources Information Center

Fonseca, James W., Comp.

Sixty-one papers are presented from the George Mason University (Virginia) annual conference on nontraditional interdisciplinary programs. They are grouped in the following categories, with three to ten papers per category: adjunct faculty; corporate/university linkages; experiential learning; graduate non-traditional programs; interdisciplinary…

Proceedings of the Annual International Conference of the Association for the Education of Teachers in Science (Costa Mesa, California, January 18-21, 2001).

ERIC Educational Resources Information Center

Rubba, Peter A., Ed.; Rye, James A., Ed.; DiBiase, Warren J., Ed.; Crawford, Barbara A., Ed.

This document contains the proceedings of the 2001 Annual International Conference of the Association for the Education of Teachers in Science which was held in Costa Mesa, California, January 18-21, 2001. Papers include: (1) "An Elementary Preservice Teacher's Search for Solutions about the Evolution-Divine Creation Question: The Story of Tracy"…

The 60th ASCD Annual Conference and Exhibit Show 2005, 2-4 April 2005: "Voices of Education--Unleashing the Power, Passion and Promise"

ERIC Educational Resources Information Center

Roberts, Brian

2005-01-01

Purpose: Aims to report on the 60th ASCD Annual Conference and Exhibit Show 2005, held in Orlando Florida, 2-4 April 2005 by the Association for Supervision and Curriculum Development. Design/methodology/approach: Discusses the presentations such as the obesity epidemic in children, educational progress in schools, creating capacity for learning,…

Proceedings of the Annual International Conference of the Association for the Education of Teachers in Science (Charlotte, North Carolina, January 10-13, 2002).

ERIC Educational Resources Information Center

Rubba, Peter A., Ed.; Rye, James A., Ed.; DiBiase, Warren J., Ed.; Crawford, Barbara A., Ed.

This document contains the proceedings of the 2002 Annual International Conference of the Association for the Education of Teachers in Science which was held in Charlotte, North Carolina, January 10-13, 2002. Papers include: (1) "Teaching Science Methods Courses with Web-Enhanced Activities" (Alec M. Bodzin); (2) "How Is Your Lawnmower Working?…

Alpha Lipoic Acid (ALA) effects on subchorionic hematoma: preliminary clinical results.

PubMed

Porcaro, G; Brillo, E; Giardina, I; Di Iorio, R

2015-09-01

The clinic use of alpha Lipoic Acid (ALA) is linked to its capability to exert antioxidant effects and, more interestingly, to counteract the pathologic changes of complex networks of cytokines, chemokines and growth factors, restoring their physiological state. The aim of this randomized controlled clinical trial was to test the contribution of oral supplementation of ALA to the standard treatment with Progesterone vaginal suppositories, in healing subchorionic hematomas in patients with threatened miscarriage. Controls were administered only Progesterone suppositories. Nineteen pregnant women in the first trimester of gestation, with threatened miscarriage and ultrasound evidence of subchorionic hematoma, were included in the trial and randomly divided in two groups: controls, treated with 400 mg Progesterone (200 mg 2 times per day), given by vaginal suppositories, and case study treated with the same Progesterone dosage, plus ALA, given orally at the dose of 600 mg (300 mg 2 times per day, DAV®, Lo.Li. Pharma srl, Italy). Sixteen patients completed the trial. Treatment was performed until complete resolution of the clinical picture. In both groups, the subjects improved significantly but, in general, a better and faster evolution in the major signs of threatened miscarriage was observed in the subjects treated with ALA and Progesterone. In these patients, the speed of resorption of subchorionic hematoma was significantly (p ≤ 0.05) superior compared to controls. The ALA and Progesterone group showed a faster decrease or disappearance of all symptoms than that observed in the control group, however the difference was not significant. These preliminary results suggest that ALA supplementation significantly contributes to speed up the process of restoration of physiological conditions in threatened miscarriage and ameliorates the medical conditions of both the mothers and the foetus, probably modulating the networks of cytokines, growth factors and other

Glacier lake outburst floods caused by glacier shrinkage: case study of Ala-Archa valley, Kyrgyz Ala Too, northern Tian Shan, Kyrgyzstan

NASA Astrophysics Data System (ADS)

Petrakov, D.; Erochin, S. A.; Harbor, J.; Ivanov, M.; Rogozhina, I.; Stroeven, A. P.; Usubaliev, R.

2012-12-01

Changes in glacier extent and runoff in Central Asia increase socio-economic stress and may result in political conflict between donors of freshwater (Kyrgyzstan, Tajikistan) and recipients of freshwater (Uzbekistan, China). Glaciers in the Pamir and Tian Shan regions have experienced an unprecedented downwasting due to regional climate changes over the past decades. This is because air temperature increases are in some areas accompanied by a decrease in precipitation. Such conditions have already resulted in a reduction of glacier runoff, especially in the northern and western Tian Shan, and an increase of the number and area of glacial lakes in Kyrgyzstan. Even though glacial lakes in the mountains are in general relatively small and located far from densely populated areas, their outbursts often produce destructive debris flows. Such debris flows are especially common in Kyrgyzstan because of its steep river channels and abundance of Holocene and Quaternary glacier deposits that can be remobilized. The glacial lake outburst flood (GLOF) in the Shakhimardan river catchment in 1999, for example, resulted in 100 fatalities in Uzbekistan, and the GLOF from the Zyndan glacial lake led to substantial economic losses in 2009. According to the latest inventory, there are more than 350 glacial lakes in Kyrgyzstan of which about 70 occur in the Kyrgyz Ala Too. The Ala-Archa valley is among the most important glacierized catchments in Kyrgyzstan. Despite the presence of a relatively small glacier-covered area of 36 km2, the Ala-Archa river is of critical importance to the Bishkek area, its agriculture, and its population which currently exceeds one million. GLOFs are therefore a threat to both numerous settlements of touristic value in the Ala-Archa headwaters and to Bishkek. The Teztor lake in the Adygene catchment of the Ala-Archa river system experienced an outburst during 1988 and 2005. On the early morning of July 31, 2012, this lake began draining through a dam

5-Aminolevulinic Acid (ALA) Alleviated Salinity Stress in Cucumber Seedlings by Enhancing Chlorophyll Synthesis Pathway.

PubMed

Wu, Yue; Jin, Xin; Liao, Weibiao; Hu, Linli; Dawuda, Mohammed M; Zhao, Xingjie; Tang, Zhongqi; Gong, Tingyu; Yu, Jihua

2018-01-01

5-Aminolevulinic acid (ALA) is a common precursor of tetrapyrroles as well as a crucial growth regulator in higher plants. ALA has been proven to be effective in improving photosynthesis and alleviating the adverse effects of various abiotic stresses in higher plants. However, little is known about the mechanism of ALA in ameliorating the photosynthesis of plant under abiotic stress. In this paper, we studied the effects of exogenous ALA on salinity-induced damages of photosynthesis in cucumber ( Cucumis sativus L.) seedlings. We found that the morphology (plant height, leave area), light utilization capacity of PS II [qL, Y(II)] and gas exchange capacity (Pn, gs, Ci, and Tr) were significantly retarded under NaCl stress, but these parameters were all recovered by the foliar application of 25 mg L -1 ALA. Besides, salinity caused heme accumulation and up-regulation of gene expression of ferrochelatase ( HEMH ) with suppression of other genes involved in chlorophyll synthesis pathway. Exogenously application of ALA under salinity down-regulated the heme content and HEMH expression, but increased the gene expression levels of glutamyl-tRNA reductase ( HEMA1 ), Mg-chelatase ( CHLH ), and protochlorophyllide oxidoreductase ( POR ). Moreover, the contents of intermediates involved in chlorophyll branch were increased by ALA, including protoporphyrin IX (Proto IX), Mg-protoporphyrin IX (Mg-Proto IX, protochlorophyllide (Pchlide), and chlorophyll (Chl a and Chl b ) under salt stress. Ultrastructural observation of mesophyll cell showed that the damages of photosynthetic apparatus under salinity were fixed by ALA. Collectively, the chlorophyll biosynthesis pathway was enhanced by exogenous ALA to improve the tolerance of cucumber under salinity.

Twenty-First Annual Conference on Manual Control

NASA Technical Reports Server (NTRS)

Miller, R. A. (Compiler); Jagacinski, R. J. (Compiler)

1986-01-01

The proceedings of the entitled conference are presented. Twenty-nine manuscripts and eight abstracts pertaining to workload, attention and errors, controller evaluation, movement skills, coordination and decision making, display evaluation and human operator modeling and manual control.

Proceedings of the sixth annual conference on fossil energy materials. Fossil Energy AR and TD Mateials Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cole, N.C.; Judkins, R.R.

1992-07-01

The Sixth Annual Conference on Fossil Energy Materials was held in Oak Ridge, Tennessee, on May 12--14, 1992. The meeting was sponsored by the US Department of Energy`s Office of Fossil Energy through the Advanced Research and Technology Development (AR&TD) Materials Program, and ASM International. The objective of the AR&TD Materials Program is to conduct research and development on materials for longer-term fossil energy applications as well as for generic needs of various fossil fuel technologies. The management of the Program has been decentralized to the DOE Field Office, Oak Ridge with Oak Ridge National Laboratory (ORNL) as the technicalmore » support contractor. The research is performed by staff members at ORNL and by a substantial number of researchers at other national laboratories, universities, and in private industry. The work is divided into the following categories: (1) ceramics, (2) development and corrosion resistance of iron aluminide, advanced austenitic and chromium-niobium alloys, and (3) technology assessment and technology transfer. This conference is held each year to review the work on all of the projects of the Program. The agenda for the meeting is given in Appendix A, and a list of attendees is presented in Appendix B. ASM International cosponsored the conference, for which we are especially grateful.« less

Building on Family Strengths: Research and Services in Support of Children and Their Families. Proceedings of the Building on Family Strengths Annual Conference (11th, Portland, Oregon, May 6-8, 2004)

ERIC Educational Resources Information Center

Gordon, Lynwood J., Ed.; Tullis, Kathryn, Ed.; Hanson, Andrea, Ed.; Sowders, Stacey, Ed.

2005-01-01

The 11th Annual Building on Family Strengths Conference was held from May 6th through May 8th, 2004, in Portland, Oregon. Highlights included: (1) The revival of a pre-conference training session; this year featured "Understanding Research and Evaluation in Relation to Social Change," presented by Elaine Slaton and Shannon CrossBear of…

Writing Our Way: Giving Voice to Adult Learning. Adult Higher Education Alliance Annual Conference Proceedings (41st, Orlando, Florida, March 9-10, 2017)

ERIC Educational Resources Information Center

Elufiede, Kemi, Ed.; Flynn, Bonnie, Ed.; Olson, Joann S., Ed.

2017-01-01

The 41st annual conference of the Adult and Higher Education Alliance (AHEA) was held at the University of Central Florida in March 2017 and explored the theme, "Writing Our Way: Giving Voice to Adult Learning." Papers in these proceedings include: (1) Transformative Learning Following Job Loss-A Dissertation Renewal (Robert Benway); (2)…

Proceedings of the Annual Conference of the International Group for the Psychology of Mathematics Education (12th, Veszprem, Hungary, July 20-25, 1988), Volume 1.

ERIC Educational Resources Information Center

Borbas, Andrea, Ed.

This proceedings from the annual conference of the International Group for the Psychology of Mathematics Education includes the following papers: "Street Mathematics and School Mathematics" (Carraher); "A Look at the Affective Side of Mathematics Learning in Hungarian Secondary Schools" (Klein & Habermann); "Beyond Constructivism: Learning…

Proceedings of the Annual Conference of the International Group for the Psychology of Mathematics Education (13th, Paris, France, July 9-13, 1989), Volume 1.

ERIC Educational Resources Information Center

International Group for the Psychology of Mathematics Education.

This proceedings of the annual conference of the International Group for the Psychology of Mathematics Education (PME) includes the following papers: "Transformations Accelerees de l'Education Scientifique Pendant la Revolution Francaise" (Jean Dhombres); "Building on the Knowledge of Students and Teachers" (Thomas P. Carpenter & Elizabeth…

A report from CPhI Worldwide 2013, Fifth Annual Pre-Connect Conference (October 22-24, 2013 - Frankfurt, Germany).

PubMed

Kuhrt, K; Gilpatrick, J

2013-11-01

A day before the start of the 2013 Conference on Pharmaceutical Ingredients (CPhI) Worldwide, the world's leading pharmaceutical networking event, a number of attendees gathered for the Fifth Annual Pre-Connect Conference to discuss trends in business development, manufacturing and regulatory arenas. Of the six modules presented at the meeting, one was dedicated to the sourcing environment in emerging markets, with special attention paid to developments in India and China. Other modules evaluated the current trends in the creation of generics and supergenerics in emerging markets. Additionally, there were updates on issues surrounding the regulatory and development hurdles that biosimilars and biobetters are facing today. Common themes for both discussions include appropriate pricing and erosion demographics for generics and biosimilars, licensing scenarios, commercialization strategies, and how to stay competitive and find novel innovations within new delivery systems, improved formulations and modifications to create better quality active pharmaceutical ingredients. Copyright 2013 Prous Science, S.A.U. or its licensors. All rights reserved.

The Caenorhabditis elegans interneuron ALA is (also) a high-threshold mechanosensor

PubMed Central

2013-01-01

Background To survive dynamic environments, it is essential for all animals to appropriately modulate their behavior in response to various stimulus intensities. For instance, the nematode Caenorhabditis elegans suppresses the rate of egg-laying in response to intense mechanical stimuli, in a manner dependent on the mechanosensory neurons FLP and PVD. We have found that the unilaterally placed single interneuron ALA acted as a high-threshold mechanosensor, and that it was required for this protective behavioral response. Results ALA was required for the inhibition of egg-laying in response to a strong (picking-like) mechanical stimulus, characteristic of routine handling of the animals. Moreover, ALA did not respond physiologically to less intense touch stimuli, but exhibited distinct physiological responses to anterior and posterior picking-like touch, suggesting that it could distinguish between spatially separated stimuli. These responses required neither neurotransmitter nor neuropeptide release from potential upstream neurons. In contrast, the long, bilaterally symmetric processes of ALA itself were required for producing its physiological responses; when they were severed, responses to stimuli administered between the cut and the cell body were unaffected, while responses to stimuli administered posterior to the cut were abolished. Conclusion C. elegans neurons are typically classified into three major groups: sensory neurons with specialized sensory dendrites, interneurons, and motoneurons with neuromuscular junctions. Our findings suggest that ALA can autonomously sense intense touch and is thus a dual-function neuron, i.e., an interneuron as well as a novel high-threshold mechanosensor. PMID:24341457

The Caenorhabditis elegans interneuron ALA is (also) a high-threshold mechanosensor.

PubMed

Sanders, Jarred; Nagy, Stanislav; Fetterman, Graham; Wright, Charles; Treinin, Millet; Biron, David

2013-12-17

To survive dynamic environments, it is essential for all animals to appropriately modulate their behavior in response to various stimulus intensities. For instance, the nematode Caenorhabditis elegans suppresses the rate of egg-laying in response to intense mechanical stimuli, in a manner dependent on the mechanosensory neurons FLP and PVD. We have found that the unilaterally placed single interneuron ALA acted as a high-threshold mechanosensor, and that it was required for this protective behavioral response. ALA was required for the inhibition of egg-laying in response to a strong (picking-like) mechanical stimulus, characteristic of routine handling of the animals. Moreover, ALA did not respond physiologically to less intense touch stimuli, but exhibited distinct physiological responses to anterior and posterior picking-like touch, suggesting that it could distinguish between spatially separated stimuli. These responses required neither neurotransmitter nor neuropeptide release from potential upstream neurons. In contrast, the long, bilaterally symmetric processes of ALA itself were required for producing its physiological responses; when they were severed, responses to stimuli administered between the cut and the cell body were unaffected, while responses to stimuli administered posterior to the cut were abolished. C. elegans neurons are typically classified into three major groups: sensory neurons with specialized sensory dendrites, interneurons, and motoneurons with neuromuscular junctions. Our findings suggest that ALA can autonomously sense intense touch and is thus a dual-function neuron, i.e., an interneuron as well as a novel high-threshold mechanosensor.

The Eighth Annual NASA/Contractors Conference and 1991 National Symposium on Quality and Productivity: Extending the boundaries of total quality management

NASA Technical Reports Server (NTRS)

Templeton, Geoffrey B. (Editor); Stewart, Lynne M. (Editor); Still, William T. (Editor)

1992-01-01

The Eighth Annual NASA/Contractors Conference and 1991 National Symposium on Quality and Productivity provided a forum to exchange knowledge and experiences in these areas of continuous improvement. The more than 1,100 attendees from government, industry, academia, community groups, and the international arena had a chance to learn about methods, tools, and strategies for excellence and to discuss continuous improvement strategies, successes, and failures. This event, linked via satellite to concurrent conferences hosted by the NASA Goddard Space Flight Center in Greenbelt, Maryland, and Martin Marietta Astronautics Group in Denver, Colorado, also explored extending the boundaries of Total Quality Management to include partnerships for quality within communities and encouraged examination, evaluation, and change to incorporate the principles of continuous improvement.

Improve efficacy of topical ALA-PDT by calcipotriol through up-regulation of coproporphyrinogen oxidase.

PubMed

Yang, Deng-Fu; Chen, Jia-Haur; Chiang, Chun-Pin; Huang, Zheng; Lee, Jeng-Woei; Liu, Chung-Ji; Chang, Junn-Liang; Hsu, Yih-Chih

2014-09-01

Topical 5-aminolevulinic acid-mediated photodynamic therapy (topical ALA-PDT) is effective for treating oral precancerous lesions. The aim of this in vivo and in vitro study was to examine whether the efficacy of topical ALA-PDT could be further improved by calcipotriol (CAL). Precancerous lesions in the buccal pouch of hamsters were induced by dimethylbenz(a)anthracene (DMBA). Lesions were treated with multiple topical ALA-PDT with or without CAL pretreatment. ALA-induced protoporphyrine IX (PpIX) was monitored by in situ fluorescence measurement. The effect of CAL on heme-related enzymes (CPOX, PPOX, and FECH) were examined in an in vitro model using human squamous cell carcinoma (SCC) cells (SCC4, SAS) using Western blots. Fluorescence spectroscopy revealed that PpIX reached its peak level in precancerous epithelial cells of buccal pouch at 2.5 or 3.5h without or with CAL pretreatment, respectively. Both treatment regimens showed similar response rates, but the complete response was achieved after 5 times of ALA-PDT and 3 times of CAL-ALA-PDT (p<0.001). Pretreatment of SCC cells with 10(-8) or 10(-7)M CAL could result in a significant cell death (p<0.05) and an elevation of CPOX protein level. Topical CAL can improve the efficacy of ALA-PDT in treating precancerous lesions, likely through the increase in CPOX level and in PpIX production. Copyright © 2014 Elsevier B.V. All rights reserved.

Vibrational and chiroptical spectroscopic characterization of gamma-turn model cyclic tetrapeptides containing two beta-Ala residues.

PubMed

Vass, Elemér; Majer, Zsuzsa; Kohalmy, Krisztina; Hollósi, Miklós

2010-08-01

The optical spectroscopic characterization of gamma-turns in solution is uncertain and their distinction from beta-turns is often difficult. This work reports systematic ECD and vibrational circular dichroism (VCD) spectroscopic studies on gamma-turn model cyclic tetrapeptides cyclo(Ala-beta-Ala-Pro-beta-Ala) (1), cyclo(Pro-beta-Ala-Pro-beta-Ala) (2) and cyclo(Ala-beta-Ala-Ala-beta-Ala) (3). Conformational analysis performed at the 6-31G(d)/B3LYP level of theory using an adequate PCM solvent model predicted one predominant conformer for 1-3, featuring two inverse gamma-turns. The ECD spectra in ACN of 1 and 2 are characterized by a negative n-->pi* band near 230 nm and a positive pi-->pi* band below 200 nm with a long wavelength shoulder. The ECD spectra in TFE of 1-3 show similar spectra with blue-shifted bands. The VCD spectra in ACN-d(3) of 1 and 2 show a +/-/+/- amide I sign pattern resulting from four uncoupled vibrations in the case of 1 and a sequence of two positive couplets in the case of 2. A -/+/+/- amide I VCD pattern was measured for 3 in TFE-d(2). All three peptides give a positive couplet or couplet-like feature (+/-) in the amide II region. VCD spectroscopy, in agreement with theoretical calculations revealed that low frequency amide I vibrations (at approximately 1630 cm(-1) or below) are indicative of a C(7) H-bonded inverse gamma-turns with Pro in position 2, while gamma-turns encompassing Ala absorb at higher frequency (above 1645 cm(-1)). Copyright 2010 Wiley-Liss, Inc.

Measuring Our Impact: What Did Our Attendees Think of Our Conference?

ERIC Educational Resources Information Center

Kramer-Vida, Louisa; Meier, Karen

2017-01-01

Peers evaluated conference presentations at an annual conference that is sponsored by two professional organizations of literacy educators in one geographic location in New York State. Conference sessions dealt with innovations and programs in schools that encouraged literacy learning. Comments from conference attendees indicated that the…

Navigating Currents and Charting Directions. Proceedings of the Annual Conference of the Mathematics Education Research Group of Australasia (31st, Brisbane, Queensland, Australia, June 28-July 1, 2008). Volumes 1 and 2

ERIC Educational Resources Information Center

Goos, Merrilyn, Ed.; Brown, Ray, Ed.; Makar, Katie, Ed.

2008-01-01

This document presents the proceedings of the 31st Annual Conference of the Mathematics Education Research Group of Australasia (MERGA). The theme of this conference is "Navigating Currents and Charting Directions." The theme reminds us that, although we are constantly pushed to account for the quality and impact of our research, we…

Proceedings of the Annual Conference of the International Group for the Psychology of Mathematics Education (19th, Recife, Brazil, July 22-27, 1995), Volume 1.

ERIC Educational Resources Information Center

Meira, Luciano, Ed.; Carraher, David, Ed.

This proceedings of the annual conference of the International Group for the Psychology of Mathematics Education (PME) includes the following plenary papers and lectures: "Student Voice in Examining 'Splitting' as an Approach to Ratio, Proportions and Fractions" (J. Confrey); "Spontaneous and Scientific Concepts in Mathematics: A Vygotskian…

Proceedings of the Annual Conference of the International Group for the Psychology of Mathematics Education (13th, Paris, France, July 9-13, 1989), Volume 2.

ERIC Educational Resources Information Center

Vergnaud, Gerard, Ed.; Rogalski, Janine, Ed.; Artique, Michele, Ed.

This proceedings of the annual conference of the International Group for the Psychology of Mathematics Education (PME) includes the following research papers: "Logo et Symetrie Centrale" (E. Gallou-Dumiel); "About Continuous Operator Subconstruct in Rational Numbers" (J. Gimenez); "Constructivist Epistemology and Discovery Learning in Mathematics"…

Non-Traditional and Interdisciplinary Programs. Selected Papers from the Annual Conference on Non-Traditional and Interdisciplinary Programs (4th, Arlington, Virginia, June 30-July 2, 1986).

ERIC Educational Resources Information Center

McGuinness, Kathleen, Comp.

A total of 50 papers are presented from the George Mason University (Virginia) fourth annual conference on nontraditional and interdisciplinary programs. They are grouped in the following major categories: adjunct faculty, corporate/university linkages, experiential learning, graduate nontraditional programs, interdisciplinary program issues,…

Engaging Minds. Proceedings of the National Academy for Integration of Research, Teaching and Learning Annual Conference (5th, Galway, Ireland, June 9-10, 2011)

ERIC Educational Resources Information Center

National Academy for Integration of Research, Teaching and Learning (NJ1), 2011

2011-01-01

This publication contains the papers presented at the 5th Annual Conference of National Academy for Integration of Research, Teaching and Learning (NAIRTL) and the 9th Galway Symposium. Presenters from across Ireland and overseas share their perspectives. The theme of engagement touches on the very heart of what a "higher" education…

5-ALA photopreparation using pulsed NIR enhances skin fluorescence via temperature-independent cell signaling pathways

NASA Astrophysics Data System (ADS)

Barolet, Augustin C.; Cormack, Gregory; Barolet, Daniel

2018-02-01

The effect of near infrared light (940 nm) on the conversion of 5-aminolevulinic acid (5-ALA) to PpIX, a compound involved in photodynamic therapy (PDT), was examined. The back skin of three test subjects was irradiated with continuous wavelength and pulsed infrared light at 940 nm. These irradiations took place 50-53, 24-29, and 8-14 hours prior to the application of the 5-ALA. After a three-hour incubation period with 5-ALA, a FluoDerm™device was used to measure the fluorescence of the skin (emitting wavelength: 400-420 nm; measuring excitation wavelength: 610-720 nm), a direct indication of the activity of 5-ALA. 5-ALA must penetrate the skin and then be converted to PpIX before any fluorescence increase can be observed. Results: For two patients (one was disqualified), the continuous wavelength, 50 hour pre-irradiation condition, the FluoDerm readings showed a 19 to 23% increase in fluorescence (p = 0.05) compared to the no-irradiation, 5-ALA only control.

Controlled self-assembling structures of ferrocene-dipeptide conjugates composed of Ala-Pro-NHCH2CH2SH chain.

PubMed

Moriuchi, Toshiyuki; Nishiyama, Taiki; Tayano, Yoshiki; Hirao, Toshikazu

2017-12-01

Bioorganometallic ferrocene-dipeptide conjugates with the Ala-Pro-cysteamine chain, Fc-L-Ala-L-Pro-NHCH 2 CH 2 SH (2) and Fc-L-Ala-D-Pro-NHCH 2 CH 2 SH (4) (Fc=ferrocenoyl), were prepared by the reduction of the ferrocene-dipeptide conjugates, Fc-L-Ala-L-Pro-cystamine-L-Pro-L-Ala-Fc (1) or Fc-L-Ala-D-Pro-cystamine-D-Pro-L-Ala-Fc (3), respectively. Control of the self-assembling structures of the ferrocene-dipeptide conjugates was demonstrated by changing the chirality of the amino acid. The molecular structure of 2 composed of the L-Ala-L-Pro-NHCH 2 CH 2 SH chain confirmed the formation of intramolecular hydrogen bond of N-H⋯N pattern between the NH of cysteamine moiety and the nitrogen of Pro moiety. Furthermore, intermolecular hydrogen bonds between NH (Ala) and CO (Pro of another molecule) and between NH (cysteamine) and CO (the ferrocenoyl moiety of another molecule) were formed, wherein each molecule is connected to four neighboring molecules by continuous intermolecular hydrogen bonds to form the hydrogen-bonded molecular assembling structure. On the contrary, the left-handed helical assembly through an intermolecular hydrogen-bonding network of 15-membered intermolecularly hydrogen-bonded ring between NH (Ala) and CO (the ferrocenoyl moiety of another molecule) and between NH (the cysteamine moiety of another molecule) and CO (Ala) was observed in the crystal packing of 4 composed of the L-Ala-D-Pro-NHCH 2 CH 2 SH chain. Copyright © 2017 Elsevier Inc. All rights reserved.

Topical application of ALA PDT for the treatment of moderate to severe acne vulgaris

NASA Astrophysics Data System (ADS)

Wang, Xiu-Li; Wang, Hong-Wei; Zhang, Ling-Lin; Su, Lina; Guo, Ming-Xia; Huang, Zheng

2009-06-01

Objectives: To evaluate the effectiveness of topical 5-aminolevulinic acid (ALA)- medicated photodynamic therapy (ALA PDT) for the treatment of moderate to severe acne vulgaris. Methods: Sixteen Chinese patients with moderate to severe facial acne were treated with 1-3 courses of ALA PDT. ALA cream (3%) was freshly prepared and applied to acne lesions for 3-4 h. The lesions were irradiated by a 635 nm diode laser at dose levels of 60 - 80 J/cm2 at 100 mW/cm2. Clinical assessments were conducted before and after treatment up to 3 months. Results: All patents showed response to ALA PDT. Complete clearance was seen in 10 patients (62.5%) and partial clearance in 6 patients (37.5%). One case showed recurrence after complete clearance at 2 months and another two showed recurrence after complete clearance at 3 months. However, the number of new lesions were significantly reduced. Adverse effects were minimal. Conclusions: The results of this preliminary clinical study is encouraging. ALA PDT is a simple, safe and useful therapeutic option for the treatment of moderate to severe acne. Further studies to evaluate the treatment with a larger number of patients and for a longer period of follow-up are needed.

Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference on Undergraduate Teaching of Psychology (5th, Ellenville, New York, March 13-15, 1991).

ERIC Educational Resources Information Center

Levine, Judith R., Ed.; Feist, Stanley C., Ed.

Selected proceedings are presented from the Fifth Annual Conference on Undergraduate Teaching of Psychology. The proceedings includes: (1) "Multimodal Self-Management: A Holistic Approach to Teaching Self-Improvement," by Edward J. O'Keefe and Donna Berger; (2) "Undergraduate Research: Statistics to Senior Presentations," by Glena L. N. Schubarth;…

Making the Difference. Proceedings of the Annual Conference of the Mathematics Education Research Group of Australasia Incorporated (22nd, Adelaide, South Australia, July 4-7, 1999).

ERIC Educational Resources Information Center

Truran, John M., Ed.; Truran, Kathleen M., Ed.

Papers from the 22nd Annual Conference of the Mathematics Education Research Group of Australasia Incorporated include the following: (1) "Making Sense of Primary Mathematics" (Gillian M. Boulton-Lewis); (2) "Seeking a Rationale for Particular Classroom Tasks and Activity" (Peter Sullivan); (3) "Research in Mathematics…

Blueprint for Success. . . A Manual for Conventions, Conferences, Seminars and Workshops.

ERIC Educational Resources Information Center

Jax, John J., Ed.

Intended to provide the guidance needed for consistent and viable annual conference planning, this manual explains how to organize and plan for a successful and profitable conference, how to determine the responsibilities and duties of conference planners and coordinators, and how to plan for specific conference events. The responsibilities of a…

The 1993 AIA/ALA Building Award Recipients.

ERIC Educational Resources Information Center

Muller, Karen

1993-01-01

Describes the eight library buildings that won the 1993 Awards of Excellence for Library Architecture from the American Institute of Architects (AIA) and the American Library Association (ALA) including one adaptive reuse, four expansions, two new buildings, and one temporary building. (EAM)

Combination therapies in adjuvant with topical ALA-mediated photodynamic therapy for DMBA-induced hamster buccal pouch premalignant lesions

NASA Astrophysics Data System (ADS)

Yang, Deng-Fu; Hsu, Yih-Chih

2012-03-01

In Taiwan, oral cancer has becomes the fastest growth male cancer disease due to the betel nut chewing habit combing with smoking and alcohol-drinking lifestyle of people. In order to eliminate the systemic phototoxic effect of 5-aminolevulinic acid (ALA), this study was designed to use a topical ALA-mediated PDT for treatment of DMBA-induced hamster buccal pouch precancerous lesions. DMBA was applied to one of the buccal pouches of hamsters thrice a week for 10 to 12 weeks. Cancerous lesions were induced and proven by histological examination. These DMBA-induced cancerous lesions were used for testing the efficacy of topical ALA-mediated PDT. Before PDT, fluorescence spectroscopy was used to determine when ALA reached its peak level in the lesional epithelial cells after topical application of ALA gel. We found that ALA reached its peak level in precancerous lesions about 2.5 hrs after topical application of ALA gel. The cancerous lesions in hamsters were then treated with topical ALA -mediated PDT with light exposure dose of 150 J/cm2 using LED 635 nm fiber-guided light device. Visual examination demonstrated that adjuvant topical ALA -mediated PDT group has shown better therapeutic results in compared to those of non-adjuvant topical ALA-mediated PDT group for DMBA-induced hamster buccal pouch precancerous lesions.

Proceedings of the Annual Conference of the International Group for the Psychology of Mathematics Education (13th, Paris, France, July 9-13, 1989), Volume 3.

ERIC Educational Resources Information Center

Vergnaud, Gerard, Ed.; Rogalski, Janine, Ed.; Artique, Michele, Ed.

This proceedings of the annual conference of the International Group for the Psychology of Mathematics Education (PME) includes the following research papers: "A Model of Understanding Two-Digit Numeration and Computation" (H. Murray & A. Olivier); "The Computer Produces a Special Graphic Situation of Learning the Change of Coordinate System" (S.…

Proceedings of the Annual Conference of the International Group for the Psychology of Mathematics Education (12th, Veszprem, Hungary, July 20-25, 1988), Volume 2.

ERIC Educational Resources Information Center

Borbas, Andrea, Ed.

The proceedings for the annual conference of the International Group for the Psychology of Mathematics Education (PME) include the following papers: "Intervention in a Mathematics Course at the College Level" (L. Gattuso & R. Lacasse); "The Education of Talented Children" (F. Genzwein); "The Development of a Model for Competence in Mathematical…

Proceedings of the Annual Conference of the International Group for the Psychology of Mathematics Education (19th, Recife, Brazil, July 22-27, 1995), Volume 2.

ERIC Educational Resources Information Center

Meira, Luciano, Ed.; Carraher, David, Ed.

This proceedings of the annual conference of the International Group for the Psychology of Mathematics Education (PME) includes the following research papers: "The Impact of Meaning on Students' Ability to Negate Statements" (T. Barnard); "A Study of the Secondary Teaching System about the Concept of Limit" (L. Espinosa & C. Azcarate);…

New developments in fluorescence detection of ALA-induced protoporphyrin IX for cancer localization

NASA Astrophysics Data System (ADS)

Stepp, Herbert G.; Baumgartner, Reinhold; Betz, Christian; Bise, Karl; Brand, P.; Gamarra, Fernando; Haeussinger, Karl; Hillemanns, Peter; Huber, Rudolf M.; Knuechel, Ruth; Kriegmair, M.; Leunig, Andreas; Pichler, J.; Rick, Kai; Schulz, H.; Stanzel, F.; Stocker, Susanne; Wagner, Simon; Weigandt, H.

1997-12-01

After the very promising clinical results for the detection of bladder cancer in urology, preclinical and clinical studies on aminolevulinic acid (5-ALA) induced protoporphyrin IX (PPIX) are preformed in various disciplines now. This paper provides a brief overview of the progress on 5-ALA assisted fluorescence diagnosis in urology, pulmonology, neurosurgery, gynecology and ENT performed in collaboration with the Laser Research Laboratory at the Department of Urology of the Ludwig-Maximilians-University in Munich. Five-ALA can be applied either topically or systemically to induce an intracellular accumulation of fluorescing PPIX. With appropriate dosage of 5-ALA, malignant tissue can be stained selectively, and irradiation with violet light excites a bright red fluorescence of the tumor. Optical properties of the tissue tend to hamper the precise identification and demarcation of suspect areas in fluorescence images. Multicolor remission and fluorescence imaging, therefore, seems to be indispensable for a reliable tumor localization.

PPARγ2Pro12Ala Polymorphism and Human Health

PubMed Central

He, Weimin

2009-01-01

The nuclear hormone receptor peroxisome proliferator activated receptor gamma (PPARγ) is an important transcription factor regulating adipocyte differentiation, lipid and glucose homeostasis, and insulin sensitivity. Numerous genetic mutations of PPARγ have been identified and these mutations positively or negatively regulate insulin sensitivity. Among these, a relatively common polymorphism of PPARγ, Pro12Ala of PPARγ2, the isoform expressed only in adipose tissue has been shown to be associated with lower body mass index, enhanced insulin sensitivity, and resistance to the risk of type 2 diabetes in human subjects carrying this mutation. Subsequent studies in different ethnic populations, however, have revealed conflicting results, suggesting a complex interaction between the PPARγ2 Pro12Ala polymorphism and environmental factors such as the ratio of dietary unsaturated fatty acids to saturated fatty acids and/or between the PPARγ2 Pro12Ala polymorphism and genetic factors such as polymorphic mutations in other genes. In addition, this polymorphic mutation in PPARγ2 is associated with other aspects of human diseases, including cancers, polycystic ovary syndrome, Alzheimer disease and aging. This review will highlight findings from recent studies. PMID:19390629

Campus Planning 1967. Selected Papers from the Annual Conference of the Society for College and University Planning (2nd, Ann Arbor, Michigan, August 20-22, 1967).

ERIC Educational Resources Information Center

Mayer, Frederick W., Ed.; Schmult, Carl V. Jr., Ed.

The annual conference encouraged communication among individuals and disciplines relating to long-range development of institutions of higher education. Ideas, comments, and major speeches were assembled and published. Major areas of interest following the introduction are--(1) college and university planning in Canada, (2) the educational…

Dreams and Dynamics. Selected Papers from the Annual Conference of the International Association of School Librarianship (22nd, Adelaide, South Australia, Australia, September 27-30, 1993).

ERIC Educational Resources Information Center

Hannesdottir, Sigrun Klara, Ed.; And Others

The themes of the 22nd Annual International Association of School Librarianship conference were: "Building a Picture of Society in the Year 2000"; "Literature--Themes of the '90s Towards the Future"; "Education--Partnerships To Develop Life-Long Learners"; and "Technology into the 21st Century." The…

Climate Leadership Awards and Conference

EPA Pesticide Factsheets

The seventh annual Climate Leadership Awards Dinner will be held during the 2018 Climate Leadership Conference; the event publicly recognize individuals and organizations for their outstanding leadership in reducing greenhouse gas emissions.

Proceedings of the 2001 Southern Mensurationists' Conference

Treesearch

Paul F. Doruska; Don C. Bragg

2000-01-01

The 2001 Southern Mensurationists' Conference was held in scenic Chattanooga, Tennessee at the historical Chattanooga Choo Choo Holiday Inn. This conference was the latest in the series of annual gatherings of southern biometricians, and attracted speakers and participants from Texas to Virginia. A variety of papers were presented and the quaint atmosphere, as...

A Content Analysis of AIAA/ITEA/ITEEA Conference Special Interest Sessions: 1978-2014

ERIC Educational Resources Information Center

Reed, Philip A.; LaPorte, James E.

2015-01-01

Associations routinely hold annual conferences to aid with professional development and actively promote the ideals of their membership and the profession they represent. The American Industrial Arts Association (AIAA) was created in 1939 and has held an annual conference the past 76 years to further these goals (Starkweather, 1995). Throughout…

Scavengers modifying the phototoxicity induced by ALA-mediated photodynamic therapy

NASA Astrophysics Data System (ADS)

Casas, Adriana; Perotti, Christian; Fukuda, Haydee; Batlle, Alcira

2001-04-01

The exogenously stimulated formation of intracellularly generated Protoporphyrin IX, a precursor of heme, is becoming one of the fastest developing areas in the field of Photodynamic Therapy (PDT). We have examined the degree of protection of several scavengers, aminoacids and compounds related to glutathione metabolism, to the photodamage induced by 5-aminolevulinic acid (ALA)-mediated PDT, employing the LM2 cell line, derived from a mammary murine adenocarcinoma. We have exposed the cells to different concentrations of the scavengers, 24 before PDT, during PDT, and 19 hr after treatment. We defined the protection grade (PG) as the ratio between cell survival after ALA-PDT treatment in the presence of the protector and cell survival after ALA-PDT treatment. We found that L-tryptophan (PG=8.3 at 2mM), N-acetyl-L-cysteine (PG= 7.9 at 30 mM), L-cysteine (PG=7.81 at 8mM), S-adenosyl-L-methionine (PG= 7.86 at 8mM), melatonin (PG=6.81 at 8mM) and glycine (PG=6.8 at 40 mM) are the best protectors to PDT damage, followed by L-methionine (PG=4.38 at 0.8 mM), mannitol (PG=2.32 at 2 mM) and reduced glutathione (PG=3.41 at 0.8 mM), whereas oxidized glutathione does not exert any protection. The implications of these results in the photodamage induced by ALA-PDT is discussed.

Harnessing cellular differentiation to improve ALA-based photodynamic therapy in an artificial skin model

NASA Astrophysics Data System (ADS)

Maytin, Edward; Anand, Sanjay; Sato, Nobuyuki; Mack, Judith; Ortel, Bernhard

2005-04-01

During ALA-based photodynamic therapy (PDT), a pro-drug (aminolevulinic acid; ALA) is taken up by tumor cells and metabolically converted to a photosensitizing intermediate (protoporphyrin IX; PpIX). ALA-based PDT, while an emerging treatment modality, remains suboptimal for most cancers (e.g. squamous cell carcinoma of the skin). Many treatment failures may be largely due to insufficient conversion of ALA to PpIX within cells. We discovered a novel way to increase the conversion of ALA to PpIX, by administering agents that can drive terminal differentiation (i.e., accelerate cellular maturation). Terminally-differentiated epithelial cells show higher levels of intracellular PpIX, apparently via increased levels of a rate-limiting enzyme, coproporphyrinogen oxidase (CPO). To study these mechanisms in a three-dimensional tissue, we developed an organotypic model that mimics true epidermal physiology in a majority of respects. A line of rat epidermal keratinocytes (REKs), when grown in raft cultures, displays all the features of a fully-differentiated epidermis. Addition of ALA to the culture medium results in ALA uptake and PpIX synthesis, with subsequent death of keratinocytes upon exposure to blue light. Using this model, we can manipulate cellular differentiation via three different approaches. (1) Vitamin D, a hormone that enhances keratinocyte differentiation; (2) Hoxb13, a nuclear transcription factor that affects the genetically-controlled differentiation program of stratifying cells (3) Hyaluronan, an abundant extracellular matrix molecule that regulates epidermal differentiation. Because the raft cultures contain only a single cell type (no blood, fibroblasts, etc.) the effects of terminal differentiation upon CPO, PpIX, and keratinocyte cell death can be specifically defined.

Eighteenth annual offshore technology conference. Volume 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1986-01-01

These sixty papers were given at a conference on offshore technology. Topics covered include friction effects of driving piles into sea beds of various compositions, wave forces on offshore platforms, stability, materials testing of various components such as plates, legs, wellheads, pipe joints, and protection of offshore platforms against ice and collision with icebergs.

Conference Scene: Personalized Medicine comes to Harvard.

PubMed

Greenberg, Tarryn

2012-01-01

The Seventh Annual Harvard Personalized Medicine Conference was held at The Joseph B Martin Conference Center at the Harvard Medical School in Boston, MA, USA on the 9-10 November 2011. The 2-day conference program was designed to highlight the impact that personalized medicine is currently making clinically as it enters the healthcare delivery system. Going forward, policies, plans and actions of stakeholders including those from government, academia and the private sector need to be informed and guided by recent experience - all of which the conference program set out to explore. The conference attracted over 600 national and international thought leaders all involved in personalized healthcare.

Bacterial resistance to vancomycin: overproduction, purification, and characterization of VanC2 from Enterococcus casseliflavus as a D-Ala-D-Ser ligase.

PubMed

Park, I S; Lin, C H; Walsh, C T

1997-09-16

The VanC phenotype for clinical resistance of enterococci to vancomycin is exhibited by Enterococcus gallinarum and Enterococcus casseliflavus. Based on the detection of the cell precursor UDP-N-acetylmuramic acid pentapeptide intermediate terminating in D-Ala-D-Ser instead of D-Ala-D-Ala, it has been predicted that the VanC ligase would be a D-Ala-D-Ser rather than a D-Ala-D-Ala ligase. Overproduction of the E. casseliflavus ATCC 25788 vanC2 gene in Escherichia coli and its purification to homogeneity allowed demonstration of ATP-dependent D-Ala-D-Ser ligase activity. The kcat/Km2 (Km2 = Km for D-Ser or C-terminal D-Ala) ratio for D-Ala-D-Ser/D-Ala-D-Ala dipeptide formation is 270/0.69 for a 400-fold selection against D-Ala in the C-terminal position. VanC2 also has substantial D-Ala-D-Asn ligase activity (kcat/Km2 = 74 mM-1min-1).

Proceedings of the Annual Conference of the International Group for the Psychology of Mathematics Education (19th, Recife, Brazil, July 22-27, 1995), Volume 3.

ERIC Educational Resources Information Center

Meira, Luciano, Ed.; Carraher, David, Ed.

This proceedings of the annual conference of the International Group for the Psychology of Mathematics Education (PME) includes the following research papers: "Some Aspects of the Construction of the Geometrical Conception of the Phenomenon of the Sun's Shadow" (P. Boero, R. Garuti, E. Lemut, T. Gazzolo, & C. Llado); "Towards the Design of a…

Politics, the Media, and the Right to Know.

ERIC Educational Resources Information Center

Berry, John; And Others

1992-01-01

Report on the 1992 American Library Association (ALA) conference discusses featured speakers, political actions of the ALA Council, guidelines on patron behavior, the resignation of ALA Executive Director Linda Crismond, and conference exhibits. Excerpts from an address by new ALA president Marilyn Miller on empowering people through libraries are…

Bridges to the Future: Building Linkages for Institutional Research. North East Association for Institutional Research Annual Conference Proceedings (27th, Pittsburgh, PA, November 4-7, 2000).

ERIC Educational Resources Information Center

North East Association for Institutional Research.

This document contains papers, summaries of panel presentations, and work share meetings from the annual conference of the North East Association for Institutional Research. The papers are: (1) "The Influence of Personality Traits, Pre-College Characteristics, and Co-Curricular Experiences on College Outcomes" (Karen W. Bauer); (2)…

Research in Science Education, Volume 1990. Selected Refereed Papers from the Annual Conference of the Australasian Science Education Research Association (21st, Perth, Western Australia, July 1990).

ERIC Educational Resources Information Center

Gardner, Paul L., Ed.

1990-01-01

This book contains selected refereed papers from the 21st Annual Conference of the Australasian Science Education Research Association. The papers are as follows: "A Learning Model for Science Education: Developing Teaching Strategies" (Appleton); "Researching Balance between Cognition and Affect in Science Teaching" (Baird et…

Visual Literacy in the Digital Age: Selected Readings from the Annual Conference of the International Visual Literacy Association (25th, Rochester, New York, October 13-17, 1993).

ERIC Educational Resources Information Center

Beauchamp, Darrel G.; And Others

This document contains selected papers from the 25th annual conference of the International Visual Literacy Association (IVLA). Topics addressed in the papers include the following: visual literacy; graphic information in research and education; evaluation criteria for instructional media; understanding symbols in business presentations;…

ALA-PDT of the normal rat esophagus: efficiency and safety largely depends on the timing of illumination

NASA Astrophysics Data System (ADS)

van den Boogert, Jolanda; de Bruin, Ron W. F.; van Staveren, Hugo J.; Siersema, Peter D.; van Hillegersberg, Richard

1999-02-01

Photodynamic therapy (PDT) is an experimental treatment modality for (pre)malignant oesophageal lesions. 5- Aminolevulinic acid (ALA)-induced, protoporphyrin IX (PpIX)- mediated photo-sensitization could be very useful as ALA- induced porphrin accumulation selectively occurs in the oesophageal epithelium. The present study aimed to optimize the time between illumination and the administration of ALA. 200 mg/kg ALA was given orally to 24 rats (allocated to 6 groups of 4 animals each). Four animals served as controls and received phosphate buffered saline orally. The animals were illuminated at various time-points (either 1, 2, 3, 4, 6, or 12 hours) after ALA administration. Illumination was performed with a cylindrical diffuser placed in a balloon catheter. The device was originally made for percutaneous transluminal coronary angioplasty and consisted of a semi-flexible catheter and an inflatable cylindric optically clear balloon. The diffuser was placed centrally in the catheter. The same illumination parameters (633 nm, 25 J radiant energy/cm diffuser, power output 100 mW/cm diffuser) were used for each animal. During illumination, fluorescence measurements and light dosimetry were performed. The animals were sacrificed at 48 hours after PDT for histological assessment. Highest PpIX fluorescence was found at 2, 3, and 4 hours after ALA administration. Dosimetric measurements showed a 2 - 3 times higher in vivo fluence rate compared to the estimated fluence rate. Histology at 48 hours after PDT showed diffuse epithelial damage at the laser site only in rats illuminated at 2 hours after ALA administration. Illumination at 3, 4, and 6 hours after ALA administration resulted in diffuse epithelial damage in only one of four rats. In none of the rats illuminated at 1 and 12 hours after administration of ALA epithelial damage was found. These results show that illumination at 2 hours after oral ALA administration provides an efficient and safe scheme for ALA-PDT in the

Languages for Today's World. DIMENSION 2006. Selected Proceedings of the 2006 Joint Conference of the Southern Conference on Language Teaching and the Florida Foreign Language Association

ERIC Educational Resources Information Center

Wilbur, Marcia L.; LeLoup, Jean W.; Ponterio, Robert; Jones, Zachary; Nuhfer-Halten, Bernice; Gordon, Kenneth A.; Gardner, Steven M.; Mentley, Carlos; Signori, Lisa F.; Heusinkveld, Paula; Burns-Hoffman, Rebecca; Jones, Jennifer; Cohn, Christie; Cherry, C. Maurice, Ed.

2006-01-01

"Dimension" is the annual volume containing the selected, refereed, edited Proceedings of each year's conference. The theme chosen for the joint conference of the Southern Conference on Language Teaching (SCOLT) and the Florida Foreign Language Association (FFLA) in Orlando, Florida, February 16-18, 2006, was "Languages for Today's…

American Bee Research Conference 2017: A short report

USDA-ARS?s Scientific Manuscript database

An overview is presented for the American Bee Research Conference (ABRC) held in January 2017 in Galveston, TX and organized by the American Association of Professional Apiculturists. The ABRC is a scientific conference focused solely on current honey bee research and held annually with one of the b...

College Learning Skills Today and Tomorrowland; Proceedings of the Annual Conference of the Western College Reading Association (8th, Anaheim, Calif., March 20-22, 1975).

ERIC Educational Resources Information Center

Sugimoto, Roy, Ed.

Articles in this publication were presented at the 1975 eighth annual COnference of the Western College Reading Association, the theme of which was "College Learning Skills Today and Tomorrowland." The keynote address presented by Gene Kerstiens was titled "The New Learners: Focus for the Future." Titles of some of the other 36 articles are:…

Mass Media Impact on Learning. 1978 Summary Report of the Annual Lake Okoboji Educational Media Leadership Conference (24th, Milford, Iowa, August 14-19, 1978).

ERIC Educational Resources Information Center

Iowa Univ., Iowa City. Audiovisual Center.

This summary report of the annual conference includes statements of participant concerns prepared for the planning committee, the keynote address on the impact of mass media on education by Nicholas Johnson with responses by Minaruth Galey and Jon Dunn, and reports from the groups which studied the seven subtopics identified in general sessions:…

Decision Making: An Imperative for Language Learning; Highlights of the Annual Language Arts Conference of Memphis State University (7th, Memphis, June 12-14, 1974).

ERIC Educational Resources Information Center

Rakes, Thomas A., Ed.; Brotherton, Sophia, Ed.

This document presents nine papers which were originally prepared for the 1974 Annual Language Arts Conference at Memphis State University. Included are: "Proxemics" by Dale F. Baltus; "Reading and Study Skill Hints for Intermediate and Secondary Teachers" by Stuart W. Bray; "A Reading Game License" by Flora C. Fowler; "Teach Kids to Think" by…

Mitochondria in health and disease - 3rd annual conference of society for mitochondrial research and medicine - 19-20 December 2013 - Bengaluru, India.

PubMed

Durhuus, Jon Ambæk; Desler, Claus; Rasmussen, Lene Juel

2015-01-01

The primary role of mitochondria was long considered to be production of cellular energy. However, as the understanding of mitochondria in disease is ever expanding, so is their additional function for a healthy organism. Mitochondrial dysfunction is linked to a range of pathologies, including cancer, neurodegenerative disorders, premature aging, diabetes and muscular diseases. Mitochondrial diseases can be hard to diagnose and treat and, therefore, interdisciplinary research and communication are important. The Third Annual Conference of Society for Mitochondrial Research and Medicine - India (SMRM) was titled "Mitochondria in Health and Disease". The conference was organized by Gayathri N, K Thangaraj, and KK Singh and was held at the National Institute of Mental Health & Neuro Sciences (NIMHANS) in Bangalore, India, from the 19th to 20th of December 2013. The meeting featured internationally renowned speakers within the field of mitochondrial research and medicine with the goal of bridging the gap between basic and clinical researchers. This review summarizes key outcomes of the conference. Copyright © 2014 © Elsevier B.V. and Mitochondria Research Society. Published by Elsevier B.V. All rights reserved.

MSaTERs: Mathematics, Science, and Technology Educators & Researchers of The Ohio State University. Proceedings of the Annual Spring Conference (3rd, Columbus, OH, May 15, 1999).

ERIC Educational Resources Information Center

Costner, Kelly M., Ed.; Reed, Michelle K., Ed.

The Mathematics, Science, and Technology Educators and Researchers of The Ohio State University (MSaTERs-OSU) is a student organization that grew out of the former OSU Council of Teachers of Mathematics (OSU-CTM). Papers from the third annual conference include: (1) "Gender, Ethnicity, and Science" (Terry Arambula-Greenfield); (2)…

D2-Thr92Ala, thyroid hormone levels and biochemical hypothyroidism in preeclampsia.

PubMed

Procopciuc, Lucia Maria; Caracostea, Gabriela; Hazi, Georgeta; Nemeti, Georgiana; Stamatian, Florin

2017-02-01

To identify if there is a relationship between the deiodinase D2-Thr92Ala genetic variant, thyroid hormone levels and biochemical hypothyroidism in preeclampsia. We genotyped 125 women with preeclampsia and 131 normal pregnant women using PCR-RFLP. Serum thyroid hormone levels were determined using ELISA. Our study showed higher TSH and FT4 levels and lower FT3 levels in women with preeclampsia compared to normal pregnant women, with statistical significance for women with mild and severe preeclampsia. The risk to develop pregnancy-induced hypertension (PIH), mild or severe preeclampsia was increased in carriers of at least one D2-Ala92 allele. TSH and FT4 levels were significantly higher and FT3 levels were significantly lower in preeclamptic women with severe preeclampsia if they carried the D2-Ala92 allele compared to non-carriers. Pregnant women with PIH and mild preeclampsia, carriers of at least one D2-Ala92 allele, delivered at lower gestational age neonates with a lower birth weight compared to non-carriers, but the results were statistically significant only in severe preeclampsia. The D2-Thr92Ala genetic variant is associated with the severity and the obstetric outcome of preeclampsia, and it also influences thyroid hormone levels. The study demonstrates non-thyroidal biochemical hypothyroidism - as a result of deiodination effects due to D2 genotypes.

Shark island pedicle flap for repair of combined nasal ala-perialar defects.

PubMed

Cvancara, Joseph L; Wentzell, J Michael

2006-05-01

The combined nasal ala-perialar defect involving the concave intersection of the lateral nasal ala, nasal sidewall, cheek, and upper cutaneous lip is a problem for reconstructive surgery. During repair of combined cheek and nose defects, it is important not to blunt the alar facial sulcus. Defects involving these adjacent cosmetic units can be repaired by using combination procedures such as a flap/graft. Our purpose is to introduce, describe, and illustrate a one-stage flap repair descriptively named the "shark" island pedicle flap (SIPF). The SIPF was developed for a specific combined nasal ala-perialar defect. This reconstruction restores the natural contours, preserves cosmetic boundaries, and eliminates the need for pexing sutures and graft/flap combinations. The SIPF is an island pedicle flap with a superior arm that rotates 90 degrees into the wound. This arm repairs the alar portion of the defect. The advancing island pedicle flap repairs the alar facial sulcus. The 90 degrees rotation of the superior arm forces the alar portion of the flap to tilt 90 degrees relative to the remaining body of the flap, forming an inverted cone of redundancy. Natural re-creation of the lateral ala and the alar facial sulcus results. Illustrative examples with a descriptive technique are provided for the SIPF. A well-planned SIPF reconstruction can provide exceptional cosmetic and functional results. Cutaneous reconstructive surgeons will find the SIPF useful and reproducible in their armamentarium for single-stage aesthetic and functional repair of a specific combined lateral ala-adjacent perialar tissue defect.

International Federation of Library Associations Annual Conference Papers. General Research Libraries Division: Parliamentary Libraries and National Libraries Sections (47th, Leipzig, East Germany, August 17-22, 1981).

ERIC Educational Resources Information Center

Gude, Gilbert; And Others

This set of papers presented to the General Research Libraries Division of the International Federation of Library Associations (IFLA) during its 47th annual conference (1981) includes: "The Effect of the Introduction of Computers on Library and Research Staff," by Gilbert Gude; "Libraries as Information Service Agencies…

Annual Copper Mountain Conferences on Multigrid and Iterative Methods, Copper Mountain, Colorado

DOE Office of Scientific and Technical Information (OSTI.GOV)

McCormick, Stephen F.

This project supported the Copper Mountain Conference on Multigrid and Iterative Methods, held from 2007 to 2015, at Copper Mountain, Colorado. The subject of the Copper Mountain Conference Series alternated between Multigrid Methods in odd-numbered years and Iterative Methods in even-numbered years. Begun in 1983, the Series represents an important forum for the exchange of ideas in these two closely related fields. This report describes the Copper Mountain Conference on Multigrid and Iterative Methods, 2007-2015. Information on the conference series is available at http://grandmaster.colorado.edu/~copper/.

Using the ALA's "Evaluating Library Instruction" (1996).

ERIC Educational Resources Information Center

Roselle, Ann

1997-01-01

Using a multi-method approach--student and faculty surveys and a comparison of bibliographies from senior nursing students--to evaluate the Information Literacy Skills Program at the University of Botswana, this study found that information about the impact of instruction can be discovered through more open-ended questions; the ALA's…

The complex filling of alae crater, Kilauea Volcano, Hawaii

USGS Publications Warehouse

Swanson, D.A.; Duffield, W.A.; Jackson, D.B.; Peterson, D.W.

1972-01-01

Since February 1969 Alae Crater, a 165-m-deep pit crater on the east rift of Kilauea Volcano, has been completely filled with about 18 million m3 of lava. The filling was episodic and complex. It involved 13 major periods of addition of lava to the crater, including spectacular lava falls as high as 100 m, and three major periods of draining of lava from the crater. Alae was nearly filled by August 3, 1969, largely drained during a violent ground-cracking event on August 4, 1969, and then filled to the low point on its rim on October 10, 1969. From August 1970 to May 1971, the crater acted as a reservoir for lava that entered through subsurface tubes leading from the vent fissure 150 m away. Another tube system drained the crater and carried lava as far as the sea, 11 km to the south. Much of the lava entered Alae by invading the lava lake beneath its crust and buoying the crust upward. This process, together with the overall complexity of the filling, results in a highly complicated lava lake that would doubtless be misinterpreted if found in the fossil record. ?? 1972 Stabilimento Tipografico Francesco Giannini & Figli.

ATIA Conference Showcases Technologies for People with Disabilities

ERIC Educational Resources Information Center

Williams, John M.

2006-01-01

The author of this article, a disability columnist, attended the Seventh Annual Assistive Technology Industry Association (ATIA) Conference, which was held in Orlando, Florida in January 2006. The author shares his impressions from the conference, and highlights new products and innovations that will help improve quality of life for people with…

The 77th National Conference on Weights and Measures

NASA Astrophysics Data System (ADS)

Brickenkamp, Carroll S.; Turner, Ann H.

1992-10-01

The 77th Annual Meeting of the National Conference on Weights and Measures (NCWM) was held July 19 through 23, 1992, at the Stouffer Nashville Hotel in Nashville, Tennessee. The theme of the meeting was 'Partnerships for Progress'. Reports by the standing and annual committees of the conference comprise the major portion of the publication, along with the addresses delivered by conference officials and other authorities from government and industry. Special meetings included those of the metrologists, the Associate Membership Committee, the Retired Officials Committee, the Scale Manufacturers' Association, the American Petroleum Institute, the Industry Committee on Packaging and Labeling, the regional weights and measure associations, and the National Association of State Departments of Agriculture Weights and Measures Division, and the National Council on State Metrication.

3rd Annual Disruptive Technology Conference

DTIC Science & Technology

2006-09-07

Innosight LLC 2 The MP3 revolution 1998 2000 2002 2003 2005 15% 3% -7% -7% ?? Annual Growth in CD sales ($) Source: RIAA Web Site; Innosight Analysis © 2006...Innovation is More Than Technology MinuteClinic: New business model iTunes : New service Dell: New process © 2006 Innosight LLC 5 Sustaining versus

Libraries, Archives, and Museums Helping Create Futures: Building on Culture, Knowledge, and Information through Collaboration and Resource Sharing. Selected Papers from PIALA 2010, Pacific Islands Association of Libraries, Archives, and Museums Annual Conference (20th, Weno, Chuuk State, Federated States of Micronesia, November 15-19, 2010)

ERIC Educational Resources Information Center

Drake, Paul B., Ed.

2012-01-01

This publication follows the tradition of publishing selected papers from Pacific Islands Association of Libraries, Archives and Museums (PIALA) annual conferences. This 20th annual conference was held in Weno, Chuuk State, Federated States of Micronesia, November 15-19, 2010. The volume begins with a listing of the members of the PIALA 2010…

THE FUNDUS PHENOTYPE ASSOCIATED WITH THE p.Ala243Val BEST1 MUTATION.

PubMed

Khan, Kamron N; Islam, Farrah; Moore, Anthony T; Michaelides, Michel

2018-03-01

To describe a highly recognizable and reproducible retinal phenotype associated with a specific BEST1 mutation-p.Ala243Val. Retrospective review of consecutive cases where genetic testing has identified p.Ala243Val BEST1 as the cause of disease. Electronic patient records were used to extract demographic, as well as functional and anatomical data. These data were compared with those observed with the most common BEST1 genotype, p.Arg218Cys. Eight individuals (six families) were identified with the p.Ala243Val BEST1 mutation and seven patients with the pathologic variant p.Arg218Cys. No patients with mutation of codon 243 knowingly had a family history of retinal disease, whereas all patients with the p.Arg218Cys variant did. The maculopathy was bilateral in all cases. The p.Ala243Val mutation was associated with a pattern dystrophy-type appearance, most visible with near-infrared reflectance and fundus autofluorescence imaging. This phenotype was never observed with any other genotype. This mutation was associated with an older median age of symptom onset (median = 42, interquartile range = 22) compared with those harboring the p.Arg218Cys mutation (median = 18, interquartile range = 12; Mann-Whitney U test; P < 0.05). Despite their older age, the final recorded acuity seemed to be better in the p.Ala243Val group (median = 0.55, interquartile range = 0.6475; median = 0.33, interquartile range = 0.358), although this did not reach statistical significance (Mann-Whitney U test; P > 0.05). The mutation p.Ala243Val is associated with highly recognizable and reproducible pattern dystrophy-like phenotype. Patients develop symptoms at a later age and tend to have better preservation of electrooculogram amplitudes.

ALA 2010: Where to Eat in DC

ERIC Educational Resources Information Center

Library Journal, 2010

2010-01-01

As host to visitors and transplants from around the world, Washington, DC, benefits from the constant infusion of different cultures. Although most neighborhoods lack a unified culinary flavor, make no mistake: DC is a city of distinctive areas, each with its own style, ensuring that hungry American Library Association (ALA) 2010 conference…

Conference report: formulating better medicines for children: 4th European Paediatric Formulation Initiative conference.

PubMed

Walsh, Jennifer; Mills, Simon

2013-01-01

The fourth annual European Paediatric Formulation Initiative (EuPFI) conference on Formulating Better Medicines for Children was held on 19-20 September 2012 at the Institute of Molecular Genetics Congress Centre, Prague, Czech Republic. The 2-day conference concentrated on the latest advances, challenges and opportunities for developing medicinal products and administration devices for pediatric use, both from European and US perspectives. It was aimed specifically at providing exposure to emerging practical applications, and for illustrating remedies utilized by pediatric drug-development teams to overcome hurdles faced in developing medicines for pediatric patients. The conference format included plenary talks, focus sessions on each of the EuPFI work streams (extemporaneous preparations, excipients, pediatric administration devices, taste masking and taste assessment, age-appropriate formulations), case studies, soapbox sessions and a parallel poster display. This conference report summarizes the keynote lectures and also gives a flavor of other presentations and posters from the conference.

Special Spotlight: 2014 AACR Conference

Cancer.gov

A focus of the 7thAACR annual conference was community engagement and how to attract and retain racial and ethnic populations. Three community health educators from CRCHD’s National Outreach Network program delivered presentations in this area.

Examining Social Presence in a Professional Online Conference

ERIC Educational Resources Information Center

Castro, Luisa F.

2016-01-01

The purpose of this multiple case study was to examine the role of social presence in a professional online conference. This study explored how presenters and attendees convey social presence and how might it influence their conference experience. The participants were presenters and attendees registered for the 21st Annual Teaching Colleges and…

MSaTERs: Mathematics, Science, and Technology Educators & Researchers of The Ohio State University. Proceedings of the Annual Spring Conference (5th, Columbus, Ohio, May 5, 2001).

ERIC Educational Resources Information Center

Herman, Marlena F., Ed.

The Mathematics, Science, and Technology Educators and Researchers of The Ohio State University (MSaTERs-OSU) is a student organization that grew out of the former Ohio State University Council of Teachers of Mathematics (OSU-CTM). Papers from the fifth annual conference include: (1) "Models of the Structure of Matter: Why Should We Care…

Reading: Focus for Enjoyment. Proceedings of the Annual Reading Conference (10th, Terre Haute, Indiana, June 12-13, 1980). Studies in Curriculum Development No. 1, 1981.

ERIC Educational Resources Information Center

Waterman, David C., Comp.; Gibbs, Vanita M., Comp.

Focusing on reading for enjoyment, the seven articles in this collection were drawn from the Tenth Annual Reading Conference held at Indiana State University. Topics discussed in the articles are: (1) reading aloud to students, (2) how to have fun while teaching vocabulary, (3) the enjoyment and affective dimensions of "EAS into Reading," (4)…

Pro12Ala PPAR γ2 gene polymorphism in PCOS women: the role of compounds regulating satiety.

PubMed

Bidzińska-Speichert, Bożena; Lenarcik, Agnieszka; Tworowska-Bardzińska, Urszula; Slęzak, Ryszard; Bednarek-Tupikowska, Grażyna; Milewicz, Andrzej

2012-03-01

Five to ten percent of women of reproductive age suffer from polycystic ovary syndrome (PCOS). Leptin, NPY, galanin, cholecystokinin (CCK) are involved in the regulation of eating behavior. PPARγ are receptors that are probably involved in hyperandrogenism. This study was designed to assess associations between the Pro12Ala PPARγ2 gene polymorphism and satiety factors in PCOS. Fifty-four PCOS women and 51 healthy women were studied. Leptin, NPY, galanin, CCK levels, and genetic studies to detect Pro12Ala PPARγ2 gene polymorphism were assessed. The leptin levels in the PCOS women carrying Pro12Ala genotype were higher than in those with Pro12Pro and Ala12Ala. The PCOS women had higher leptin and NPY levels and lower galanin levels. Obese PCOS patients had lower CCK levels. In the PCOS women, a single Ala allele may have a protective role as far as hyperleptinemia is concerned. The PCOS women may reveal a disrupted central leptin/NPY feedback loop with some shifts in food intake.

Photodynamic therapy (PDT) and photodiagnosis (PD) using endogenous photosensitization induced by 5-aminolevulinic acid (ALA): current clinical and development status

NASA Astrophysics Data System (ADS)

Marcus, Stuart L.; Sobel, Russel S.; Golub, Allyn L.; Carroll, Ronald L.; Lundahl, Scott L.; Shulman, D. Geoffrey

1996-04-01

Exogenous provision of ALA to many tissues results in the accumulation of sufficient quantities of the endogenous photosensitizer protoporphyrin IX, (PpIX), to produce a photodynamic effect. Therefore, ALA may be considered the only current PDT agent in clinical development which is a biochemical precursor of a photosensitizer. Topical ALA application, followed by exposure to activating light (ALA PDT), has been reported effective for the treatment of a variety of dermatologic diseases including cutaneous T-cell lymphoma, superficial basal cell carcinoma, Bowen's disease, and actinic (solar) keratoses, and is also being examined for treatment of acne and hirsutism. PpIX induced by ALA application also may serve as a fluorescence detection marker for photodiagnosis (PD) of malignant and pre- malignant conditions of the urinary bladder and other organs. Local internal application of ALA has also been used for selective endometrial ablation in animal model systems and is beginning to be examined in human clinical studies. Systemic, oral administration of ALA has been used for ALA PDT of superficial head and neck cancer, various gastrointestinal cancers, and the condition known as Barrett's esophagus. This brief paper reviews the current clinical and development status of ALA PDT.

Potentiation of ALA-PDT antitumor activity in mice using topical DMXAA

NASA Astrophysics Data System (ADS)

Marrero, Allison; Sunar, Ulas; Sands, Theresa; Oseroff, Allan; Bellnier, David

2009-06-01

Photodynamic treatment of subcutaneously implanted Colon 26 tumors in BALB/c mice using the aminolevulinic acid (ALA)-induced photosensitizer protoporphyrin IX (PpIX) was shown to be enhanced by the addition of the vascular disrupting agent 5,6-Dimethylxanthenone-4-acetic-acid (DMXAA; Novartis ASA404). DMXAA increases vascular permeability and decreases blood flow in both murine and human tumors. Sufficiently high parenteral DMXAA doses can lead to tumor collapse and necrosis. We have previously reported marked enhancement of antitumor activity when PDT, using either Photofrin or HPPH, is combined with low-dose intraperitoneal DMXAA. We now describe the first attempt to combine topically-applied DMXAA with PDT. For this, DMXAA was applied two hours before PpIX-activating light delivery. PDT with ALA-PDT alone (ALA 20%; 80 J/cm2 delivered at 75 mW/cm2) caused a 39% decrease in tumor volume compared to unirradiated controls. Addition of topical DMXAA to ALA-PDT resulted in a 74% reduction in tumor volume. Diffuse correlation spectroscopy (DCS), a non-invasive blood flow imaging method, is being used to understand the mechanism of this effect and to aid in the proper design of the therapy. For instance, our most recent DCS data suggests that the 2-hour interval between the DMXAA and light applications may not be optimum. This preliminary study suggests a potential role for topical DMXAA in combination with PDT for dermatologic tumors.

Proceedings of the Annual Conference of the International Group for the Psychology of Mathematics Education (9th, Noordwijkerhout, The Netherlands, July 22-29, 1985), Volume 1: Individual Contributions.

ERIC Educational Resources Information Center

Streefland, Leen, Ed.

This proceedings of the annual conference of the International Group for the Psychology of Mathematics Education (PME) includes the following research papers: "Calculators in Primary Education" (van den Brink); "Microworlds and Van Hiele Levels" (Dreyfus, Thompson); "Dynamical Mazes and the Ob-Serving Computer" (Harmegnies, Lowenthal); "Iterative…

Summaries from the Eleventh Annual Houston Conference on AIDS in America.

PubMed

1999-07-01

A number of significant papers from the Eleventh Annual Houston Conference on AIDS in America are summarized. Topics include the current concepts in pathogenesis of HIV infection, the use of anti-HIV therapies, and drug interactions in HIV treatment. A session on HIV disease in children focused on the epidemiology and prevention of vertical transmission with Zidovudine, when to initiate therapy, and options for children who have failed current therapies. Studies using immune-based therapy have shown promise in treating HIV disease. New data from a study with sargramostim, an investigational agent for opportunistic infection prophylaxis, shows that the drug reduces viral loads and delays time to treatment failure. Pentafuside (T-20), the first of a new class of HIV drugs, fusion inhibitors, has been found to be safe and effective against HIV, although drug resistance may be associated with its use. Other sessions summarized progress in clearing HIV from viral reservoirs, the ethics of HIV research support from the drug industry and drug marketing, and a review of immune reconstitution studies among people on antiretroviral therapy. Sam Avrett of the AIDS Vaccine Advocacy Coalition (AVAC) summarized in his session the characteristics of a successful HIV vaccine and the need to have more people involved in vaccine advocacy as a means to ending the epidemic. Contact information is provided.

Fluorescence spectroscopy of gastrointestinal tumors using δ-ALA

NASA Astrophysics Data System (ADS)

Borisova, E. G.; Vladimirov, B. G.; Angelov, I. G.; Avramov, L. A.

2007-03-01

In the recent study delta-aminolevulinic acid/Protoporphyrin IX (δ-ALA/PpIX) is used as fluorescent marker for dysplasia and tumor detection in esophagus and stomach. The δ-ALA is administered per os six hours before measurements at dose 20mg/kg weight. High-power light-emitting diode at 405 nm is used as an excitation source. Special opto-mechanical device is built to use the light guide of standard video-endoscopic system (Olimpus Corp.). Through endoscopic instrumental channel a fiber is applied to return information about fluorescence to microspectrometer (USB4000, OceanOptics Inc.). The fluorescence detected from tumor sites has very complex spectral origins. It consists of autofluorescence, fluorescence from exogenous fluorophores and re-absorption from the chromophores accumulated in the tissue investigated. Mucosa autofluorescence lies at 450-600 nm region. The fluorescence of PpIX is clearly pronounced at the 630-710 nm region. Deep minima in the tumor fluorescence signals are observed in the region 540-575 nm, related to hemoglobin re-absorption. Such high hemoglobin content is an indication of the tumors neovascularisation and it is clearly pronounced in all dysplastic and tumor sites investigated. The lack of fluorescence peaks in the red spectral area for normal mucosa is an indication for selective accumulation of δ-ALA/PpIX only in abnormal sites and gives high contrast when lesion borders are determined from clinicians during video observation in the process of diagnostic procedure. Very good correlation between fluorescence signals and histology examination results of the lesions investigated is achieved.

Second Annual Practitioners Conference on Energy Education. Proceedings.

ERIC Educational Resources Information Center

Hofman, Helenmarie H., Ed.; Miller, F. Gene, Ed.

Reported are the proceedings of a conference of practitioners of energy education including classroom teachers, curriculum experts, administrators, and representatives from industry and government. Participants worked in six groups to produce papers and recommendations. Topics addressed by each group included: (1) State-of-the-Art and Needs…

National Defense Industrial Association Disruptive Technologies Conference

DTIC Science & Technology

2009-10-14

NDIA Disruptive Technologies 10/16/2009 Page-1 National Defense Industrial Association Disruptive Technologies Conference 14 October 2009 The...SUPPLEMENTARY NOTES Presented at the 6th Annual Disruptive Technologies Conference, 14-15 oct 2009, Washington, DC 14. ABSTRACT 15. SUBJECT TERMS 16...of conflict NDIA Disruptive Technologies 10/16/2009 Page-3 DDR&E Imperatives 1. Accelerate delivery of technical capabilities to win the current

Association between the Pro12Ala polymorphism of peroxisome proliferator-activated receptor gamma 2 and inflammatory bowel disease: a meta-analysis.

PubMed

Zhang, Zhi-Feng; Yang, Ning; Zhao, Gang; Zhu, Lei; Wang, Li-Xia

2012-01-01

Peroxisome proliferator-activated receptor gamma (PPARγ), a nuclear receptor, has been implicated playing a role in the development of inflammatory bowel disease (IBD). However, previous studies evaluating the association between the PPARγ2 Pro12Ala polymorphism and IBD are inconsistent. We performed a meta-analysis to determine whether the PPARγ2 Pro12Ala mutation was associated with the presence of IBD. Electronic databases were searched for case-control studies evaluating the association between the Pro12Ala mutation and the presence of IBD. Effects were summarized with the methods recommended by the Cochrane Collaboration. A total of 7 studies including 1002 ulcerative colitis (UC) cases, 1090 Crohǹs disease (CD) cases and 1983 controls were involved in this meta-analysis. In the overall analysis, no significant association of this polymorphism with UC or CD was found. In the subgroup analyses in different populations, AlaAla genotype seemed to protect the European Caucasian population against the development of CD (Pro vs Ala: OR = 1.135, 95%CI = 0.951-1.354, P = 0.162, Bon = 1.000; ProPro vs ProAla: OR = 1.042, 95%CI = 0.852-1.273, P = 0.690, Bon = 1.000; ProPro vs AlaAla: OR = 2.379, 95%CI = 1.110-5.100, P = 0.026, Bon = 0.156; ProAla vs AlaAla: OR = 2.315, 95%CI = 1.064-5.037, P = 0.034, Bon = 0.204; Pro homozygotes vs Ala positives: OR = 1.094, 95%CI = 0.899-1.330, P = 0.371, Bon = 1.000; Pro positives vs Ala homozygotes: OR = 2.360, 95%CI = 1.103-5.053, P = 0.027, Bon = 0.162; heterozygotes vs all homozygotes: OR = 0.976, 95%CI = 0.799-1.192, P = 0.809, Bon = 1.000). There was no significant association of this polymorphism with UC or CD in the East Asian population and the Turkish population. AlaAla genotype may be a protective factor in the European Caucasian population against the development of CD in a recessive way.

Sixth Annual Users' Conference. [Transportable Applications Executive (TAE)

NASA Technical Reports Server (NTRS)

Szczur, Martha (Editor); Harris, Elfrieda (Editor)

1986-01-01

Conference papers and presentation outlines which address the use of the Transportable Applications Executive (TAE) and its various applications programs are compiled. Emphasis is given to the design of the user interface and image processing workstation in general. Alternate ports of TAE and TAE subsystems are also covered.

Proceedings of the Annual National Conference on Ada (Trade Name) Technology (4th) Held in Atlanta, Georgia on 19-20 March 1986.

DTIC Science & Technology

1986-01-01

classe’s for dlifferentt target miitect t e . It i. itilir"t atlt tiundersltattd t~ lat thi is for OIIVC~jiV( 1 - ill his exForiitileIl tileiii...variable in the programming use bgcolor maroon, fgcolor (RGB 1 .9 .2) language. Another occasion where a user may want bordercolor ( HSV .6 .5 .7) to...AD-Ai67 U2 PROCEEDINGS OF THE ANNUAL NATIONAL CONFERENCE ON ADA 1 /2 (TRADE NAME) TECHNOL..(U) ARMY COMMUNICATIONS-ELECTRONICS COMMAND FORT MONMOUTH

Proceedings of the Annual Conference of Psychologists in the Army Medical Service (4th) Held in New York, New York on August 30, 1961

DTIC Science & Technology

1986-02-01

Seturity CWcatio•i (U) Proceedings Fourth Annual Conference of Psychologists it: The Army Medical Service, August, 1961 12. PERSONAL AUeTHORIS WILKIN...direction of personal satisfaction in his job. These can be simed up briefly as effective management and effective communication. Whenever an...to an inexperienced individual while at the same time you would be unresponsible tor the outcome except as it affects all persons called upon to read

Conference scene: DGVS spring conference 2009.

PubMed

Kolligs, Frank Thomas

2009-10-01

The 3rd annual DGVS Spring Conference of the German Society for Gastroenterology (Deutsche Gesellschaft für Verdauungs- und Stoffwechselkrankheiten) was held at the Seminaris Campus Hotel in Berlin, Germany, on 8-9 May, 2009. The conference was organized by Roland Schmid and Matthias Ebert from the Technical University of Munich, Germany. The central theme of the meeting was 'translational gastrointestinal oncology: towards personalized medicine and individualized therapy'. The conference covered talks on markers for diagnosis, screening and surveillance of colorectal cancer, targets for molecular therapy, response prediction in clinical oncology, development and integration of molecular imaging in gastrointestinal oncology and translational research in clinical trial design. Owing to the broad array of topics and limitations of space, this article will focus on biomarkers, response prediction and the integration of biomarkers into clinical trials. Presentations mentioned in this summary were given by Matthias Ebert (Technical University of Munich, Germany), Esmeralda Heiden (Epigenomics, Berlin, Germany), Frank Kolligs (University of Munich, Germany), Florian Lordick (University of Heidelberg, Germany), Hans Jorgen Nielsen (University of Copenhagen, Denmark), Anke Reinacher-Schick (University of Bochum, Germany), Christoph Röcken (University of Berlin, Germany), Wolff Schmiegel (University of Bochum, Germany) and Thomas Seufferlein (University of Halle, Germany).

FAA Administrator Babbitt Speaks at Conference

NASA Image and Video Library

2011-02-09

Randy Babbitt, Administrator of the Federal Aviation Administration gives opening remarks at the 14th Annual FAA Commercial Space Transportation Conference at the Washington Convention Center on Wednesday, Feb. 9, 2001. Photo Credit: (NASA/Carla Cioffi)

Association of Pro12Ala Polymorphism of Peroxisome Proliferator-Activated Receptor gamma 2 (PPARγ2) Gene with Type 2 Diabetes Mellitus in Ethnic Kashmiri Population.

PubMed

Majid, Misbah; Masood, Akbar; Kadla, Showkat Ahmad; Hameed, Iqra; Ganai, Bashir A

2017-02-01

Type 2 diabetes mellitus (T2DM) is characterized by chronic hyperglycemia associated with insulin resistance and relative insulin deficiency. T2DM is believed to be attributable to the combined effect of genetic and environmental factors. Peroxisome proliferator-activated receptor gamma 2 (PPARγ2) is one of the main candidate genes that are implicated in T2DM. A common proline 12 alanine (Pro12Ala) polymorphism in PPARγ2 has been shown to be associated with T2DM. The aim of this work was to investigate the possible role of PPARγ2 gene polymorphism, as a genetic risk factor for T2DM. The study comprised 200 ethnic unrelated subjects (100 T2DM patients and 100 controls). PCR-RFLP technique was used for genotyping analysis. The frequency of the Pro allele was 79 and 91.5 % for controls and cases, respectively (P < 0.05; OR 3.2; 95 % CI 1.64-6.3). The Pro12Ala polymorphism was in Hardy-Weinberg equilibrium in both patients and controls (χ 2  = 0.13, P > 0.05). We found a significant association of Pro12Ala polymorphism of PPARγ2 gene with T2DM, however the genotypes showed statistically significant association only with few clinical parameters including body mass index, total cholesterol, and low-density lipoprotein (P < 0.05). The study signifies that Pro allele in PPARγ2 may be a genotypic risk factor that confers susceptibility to T2DM in ethnic Kashmiri population.

Lifelong imbalanced LA/ALA intake impairs emotional and cognitive behavior via changes in brain endocannabinoid system

PubMed Central

Zamberletti, Erica; Piscitelli, Fabiana; De Castro, Valentina; Murru, Elisabetta; Gabaglio, Marina; Colucci, Paola; Fanali, Chiara; Prini, Pamela; Bisogno, Tiziana; Maccarrone, Mauro; Campolongo, Patrizia; Banni, Sebastiano; Rubino, Tiziana; Parolaro, Daniela

2017-01-01

Imbalanced dietary n-3 and n-6 PUFA content has been associated with a number of neurological conditions. Endocannabinoids are n-6 PUFA derivatives, whose brain concentrations are sensitive to modifications of fatty acid composition of the diet and play a central role in the regulation of mood and cognition. As such, the endocannabinoid system appears to be an ideal candidate for mediating the effects of dietary fatty acids on mood and cognition. Lifelong administration of isocaloric α-linolenic acid (ALA)-deficient and -enriched diets induced short-term memory deficits, whereas only dietary ALA enrichment altered emotional reactivity in adult male rats compared with animals fed a standard diet that was balanced in ALA/linoleic acid (LA) ratio. In the prefrontal cortex, both diets reduced 2-AG levels and increased MAG lipase expression, whereas only the enriched diet reduced AEA levels, simultaneously increasing FAAH expression. In the hippocampus, an ALA-enriched diet decreased AEA content and NAPE-PLD expression, and reduced 2-AG content while increasing MAG lipase expression. These findings highlight the importance of a diet balanced in fatty acid content for normal brain functions and to support a link between dietary ALA, the brain endocannabinoid system, and behavior, which indicates that dietary ALA intake is a sufficient condition for altering the endocannabinoid system in brain regions modulating mood and cognition. PMID:27903595

International Perspectives on Education. BCES Conference Books, Volume 10

ERIC Educational Resources Information Center

Popov, Nikolay, Ed.; Wolhuter, Charl, Ed.; Leutwyler, Bruno, Ed.; Hilton, Gillian, Ed.; Ogunleye, James, Ed.; Almeida, Patrícia Albergaria, Ed.

2012-01-01

This volume contains papers submitted to the 10th Annual Conference of the Bulgarian Comparative Education Society, held in Kyustendil, Bulgaria, 12-15 June 2012. The overall goal of the 10th BCES conference is to facilitate discussion of different perspectives on international education providing a forum for scientific debate and constructive…

Five Decades of ALER Conference Session Presentations, 1960-2010

ERIC Educational Resources Information Center

Still, Kristine Lynn; Gordon, Jaclyn Prizant

2011-01-01

The purpose of this study was to conduct a quantitative content analysis of the conference session programs from the Association of Literacy Educators and Researchers (ALER) annual meetings across five decades spanning from 1960 through 2010. The data cycled through an analysis during four separate phases. In total, 4,605 conference sessions were…

Basic principles of fluorescence detection with use of 5-ALA

NASA Astrophysics Data System (ADS)

Baumgartner, Reinhold; Stepp, Herbert G.

2000-06-01

5-Aminolevulinic acid (5-ALA) has been proven to induce selective accumulation of flourescent Protoporphyrin IX (PPIX) in many types of malignant tissue. According to the target to treatment different routes of topical and systemical application of 5-ALA can be chosen. They include techniques like inhalation, installation and rinsing. For fluorescence detection a lamp based system have been developed in the laser-Forschungslabor in Munich together with Storz company. By skillful balancing of excitation filter centered around 400 nm and the observation filter with transmission above 450 nm images with high color contrast can be obtained. The universal application of the D-LIGHT could be demonstrated in different clinical disciplines like urology, neurosurgery, ENT clinic, gynecology and others.

Gaining New Insights - Building on Experience. Selected Papers from the Annual Conference of the North American Association for Environmental Education (24th, Portland, Maine, September 15-20, 1995).

ERIC Educational Resources Information Center

Slocombe, D. Scott, Ed.

This document contains selected papers from the 24th annual conference of the North American Association for Environmental Education (NAAEE). Papers and reports from the NAAEE Sections and other special workshops are presented first, followed by contributed papers, and finally a section providing background information on the NAAEE. Various topics…

The Importance of Quality in the CEU. Proceedings of the Annual Conference of the Council on the Continuing Education Unit (2nd, Memphis, Tennessee, June 12-13, 1980).

ERIC Educational Resources Information Center

Medick, Glenn A., Ed.

These proceedings contain twenty-one presentations made at the Second Annual Conference of the Council on the Continuing Education Unit (CEU). The opening speeches--Introduction to the CEU and Future Directions for a Learning Society--are followed by the panel discussion presentation, The CEU: Can It Withstand Scrutiny?, and two respondent…

Delta-aminolevulinic acid dehydratase (ALAD) polymorphism in lead exposed Bangladeshi children and its effect on urinary aminolevulinic acid (ALA)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tasmin, Saira, E-mail: rimzim1612@yahoo.com; Furusawa, Hana; Ahmad, Sk. Akhtar

Background and objective: Lead has long been recognized as a harmful environmental pollutant. People in developing countries like Bangladesh still have a higher risk of lead exposure. Previous research has suggested that the delta-aminolevulinic acid dehydratase (ALAD) genotype can modify lead toxicity and individual susceptibility. As children are more susceptible to lead-induced toxicity, this study investigated whether the ALAD genotype influenced urinary excretion of delta-aminolevulinic acid (U-ALA) among children exposed to environmental lead in Bangladesh. Methods: Subjects were elementary schoolchildren from a semi-urban industrialized area in Bangladesh. A total of 222 children were studied. Blood and urine were collected tomore » determine ALAD genotypes, blood lead levels and urinary aminolevulinic acid (U-ALA). Results: The mean BPb level was 9.7 µg/dl for the study children. BPb was significantly positively correlated with hemoglobin (p<0.01). In total, allele frequency for ALAD 1 and 2 was 0.83 and 0.17 respectively. The mean U-ALA concentration was lower in ALAD1-2/2-2 carriers than ALAD1-1 carriers for boys (p=0.001). But for girls, U-ALA did not differ significantly by genotype (p=0.26). When U-ALA was compared by genotype at the same exposure level in a multiple linear regression analysis, boys who were ALAD1-2/2-2 carriers still had a lower level of U-ALA compared to ALAD1-1carriers. Conclusion: This study provides information about the influence of ALAD polymorphism and its association with U-ALA in Bangladeshi children. Our results indicate that the ALAD1-2/2-2 genotype may have a protective effect in terms of U-ALA for environmentally lead exposed boys. - Highlights: • High blood lead level for the environmentally exposed schoolchildren. • BPb was significantly correlated with U-ALA and Hb. • Effect of ALAD genotype on U-ALA is differed by sex. • Lower U-ALA in ALAD2 than ALAD1 carriers only for boys at same exposure.« less

May 20, 2016 Administrator Bolden Press Conference at Marshall

NASA Image and Video Library

2016-05-20

NASA Administrator Charles Bolden presented the Small Business Administrator's Cup -- awarded for managing the agency's most effective small business program -- to NASA's Marshall Space Flight Center in Huntsville, Ala. It is the fifth time in eight years Marshall has earned the prize, which honors innovative practices that promote small business participation in a variety of NASA initiatives, and recognizes the winning center's significant contributions to the agency's small business programs. The award is sponsored annually by NASA's Office of Small Business Programs. Following the award ceremony, Bolden met with the media.

Evidence for greater oxidative substrate flexibility in male carriers of the Pro 12 Ala polymorphism in PPARgamma2.

PubMed

Thamer, C; Haap, M; Volk, A; Maerker, E; Becker, R; Bachmann, O; Machicao, F; Häring, H U; Stumvoll, M

2002-03-01

The Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma2 (PPARgamma2) gene is associated with reduced type 2 diabetes risk and increased insulin sensitivity. It is possible that the oxidative shift from lipid to glucose as a fuel is more efficient in Ala allele carriers. To test this hypothesis, we examined carbohydrate and lipid oxidation by indirect calorimetry in lean, glucose tolerant subjects with (X/Ala, n = 25) and without the Pro12Ala polymorphism (Pro/Pro, n = 73) basally and after insulin stimulation during a 2-hour eugylcaemic hyperinsulinaemic clamp. Insulin sensitivity was non-significantly greater in X/Ala (0.13 +/- 0.01 micromol/kg/min/pM) than in Pro/Pro (0.12 +/- 0.01 micromol/kg/min/pM, p = 0.27). Basally, there were no lipid nor carbohydrate oxidation differences between the groups. Interestingly, the decrease in lipid oxidation during insulin stimulation was significantly greater in male X/Ala (- 0.51 +/- 0.06 mg/kg/min) than in male Pro/Pro (- 0.35 +/- 0.04 mg/kg/min, p = 0.03). No difference was observed in females. Analogously, the change in carbohydrate oxidation in male X/Ala (1.34 +/- 0.2 mg/kg/min) was significantly greater than in male Pro/Pro (1.03 +/- 0.12 mg/kg/min, p = 0.05). The respiratory quotient increased more, but not significantly more, in male X/Ala (0.11 +/- 0.01) than in male Pro/Pro subjects (0.08 +/- 0.01, p = 0.08) but similarly in females. These results indicate that the mechanism by which the Ala allele improves insulin sensitivity might involve enhanced suppression of lipid oxidation permitting more efficient (predominantly non-oxidative) glucose disposal. It is unclear why this could be demonstrated only in males, although gender differences in substrate oxidation are well documented.

Association between the Pro12Ala Polymorphism of Peroxisome Proliferator-Activated Receptor Gamma 2 and Inflammatory Bowel Disease: A Meta-Analysis

PubMed Central

Zhao, Gang; Zhu, Lei; Wang, Li-Xia

2012-01-01

Background Peroxisome proliferator-activated receptor gamma (PPARγ), a nuclear receptor, has been implicated playing a role in the development of inflammatory bowel disease (IBD). However, previous studies evaluating the association between the PPARγ2 Pro12Ala polymorphism and IBD are inconsistent. We performed a meta-analysis to determine whether the PPARγ2 Pro12Ala mutation was associated with the presence of IBD. Methods and Findings Electronic databases were searched for case-control studies evaluating the association between the Pro12Ala mutation and the presence of IBD. Effects were summarized with the methods recommended by the Cochrane Collaboration. A total of 7 studies including 1002 ulcerative colitis (UC) cases, 1090 Crohǹs disease (CD) cases and 1983 controls were involved in this meta-analysis. In the overall analysis, no significant association of this polymorphism with UC or CD was found. In the subgroup analyses in different populations, AlaAla genotype seemed to protect the European Caucasian population against the development of CD (Pro vs Ala: OR = 1.135, 95%CI = 0.951–1.354, P = 0.162, Bon = 1.000; ProPro vs ProAla: OR = 1.042, 95%CI = 0.852–1.273, P = 0.690, Bon = 1.000; ProPro vs AlaAla: OR = 2.379, 95%CI = 1.110–5.100, P = 0.026, Bon = 0.156; ProAla vs AlaAla: OR = 2.315, 95%CI = 1.064–5.037, P = 0.034, Bon = 0.204; Pro homozygotes vs Ala positives: OR = 1.094, 95%CI = 0.899–1.330, P = 0.371, Bon = 1.000; Pro positives vs Ala homozygotes: OR = 2.360, 95%CI = 1.103–5.053, P = 0.027, Bon = 0.162; heterozygotes vs all homozygotes: OR = 0.976, 95%CI = 0.799–1.192, P = 0.809, Bon = 1.000). There was no significant association of this polymorphism with UC or CD in the East Asian population and the Turkish population. Conclusion AlaAla genotype may be a protective factor in the European Caucasian population against the

The Second Annual Primary Care Conference--Programming to eliminate health disparities among ethnic minority populations: an introduction to proceedings.

PubMed

Heisler, Michael; Blumenthal, Daniel S; Rust, George; Dubois, Anne M

2003-01-01

From October 31, 2002 through November 2, 2002, the Second Annual Primary Care Conference was held, sponsored by the Morehouse School of Medicine's National Center for Primary Care and its Prevention Research Center. The conference was designed as a collaborative activity with the Atlanta Regional Health Forum; The Carter Center; Emory University's School of Medicine, Nell Hodgson Woodruff School of Nursing, and Rollins School of Public Health; Georgia Chapter of the American College of Physicians/American Society of Internal Medicine; Georgia Nurses Foundation; Southeastern Primary Care Consortium, Inc./Atlanta Area Health Education Center; St. Joseph's Mercy Care Services; United States Department of Health and Human Services: Agency for Healthcare Research and Quality; Centers for Disease Control and Prevention; Health and Human Services (Region IV); Health Resources and Services Administration; Office of Minority Health (Region IV); and Office on Women's Health (Region IV). The 2 and a half-day conference featured 5 plenary sessions and 3 tracks of medical education for primary care physicians and other healthcare providers. The tracks were categorized as: Track A: Adult Health; Track B: Public Health and Prevention; and Track C: Maternal/Child/Youth Health. Within each track, 6 working sessions were presented on topic areas including diabetes, obesity, cardiovascular disease, cancer, mental health, infectious disease, behavioral and social health, women's health, stroke, and asthma. A total of 18 working sessions took place and each working session included 3 presentations. Continuing medical education credits or continuing education units were granted to participants. In all, 485 individuals participated in the conference, with the majority of the participants from the southeastern United States. Of the attendees, 35% were physicians (MD); 13% were nurses (RN); 12% held master-level degrees; and 12% held other doctorate-level degrees.

Comparsion of light dose on topical ALA-mediated photodynamic therapy for DMBA-induced hamster buccal pouch premalignant lesions

NASA Astrophysics Data System (ADS)

Yang, Deng-Fu; Tseng, Meng-Ke; Liu, Chung-Ji; Hsu, Yih-Chih

2012-03-01

Oral cancer has becomes the most prominent male cancer disease due to the local betel nut chewing habit combing with smoking and alcohol-drinking lifestyle. In order to minimize the systemic phototoxic effect of 5-aminolevulinic acid (ALA), this study was designed to use a topical ALA-mediated PDT for treatment of DMBA-induced hamster buccal pouch cancerous lesions. DMBA was applied to one of the buccal pouches of hamsters thrice a week for 8 to 10 weeks. Precancerous lesions were induced and proven by histological examination. These DMBA-induced cancerous lesions were used for testing the efficacy of topical ALA -mediated PDT. We found that ALA reached its peak level in cancerous lesions about 2.5 hrs after topical application of ALA gel. The precancerous lesions in hamsters were then treated with topical ALA -mediated PDT with light exposure dose of 75 and 100 J/cm2 using LED 635 nm Wonderlight device. It is suggesting that optimization of the given light dose is critical to the success of PDT results.

Association between the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor gamma gene and strength athlete status.

PubMed

Maciejewska-Karlowska, Agnieszka; Sawczuk, Marek; Cieszczyk, Pawel; Zarebska, Aleksandra; Sawczyn, Stanislaw

2013-01-01

The 12Ala allele of the Peroxisome Proliferator-Activated Receptor gamma gene (PPARG) Pro12Ala polymorphism produces a decreased binding affinity of the PPARγ2 protein, resulting in low activation of the target genes. The 12Ala allele carriers display a significantly improved insulin sensitivity that may result in better glucose utilisation in working skeletal muscles. We hypothesise that the PPARG 12Ala allele could be associated with strength athlete status in Polish athletes. The genotype distribution of PPARG Pro12Ala was examined in 660 Polish athletes. The athletes were stratified into four subgroups: endurance, strength-endurance, sprint-strength and strength. Control samples were prepared from 684 unrelated sedentary volunteers. A χ(2) test was used to compare the PPARG Pro12Ala allele and genotype frequencies between the different groups of athletes and control subjects. Bonferroni's correction for multiple testing was applied. A statistically significant higher frequency of PPARG 12Ala alleles was observed in the subgroup of strength athletes performing short-term and very intense exertion characterised by predominant anaerobic energy production (13.2% vs. 7.5% in controls; P = 0.0007). The PPARG 12Ala allele may be a relevant genetic factor favouring strength abilities in professional athletes, especially in terms of insulin-dependent metabolism, a shift of the energy balance towards glucose utilisation and the development of a favourable weight-to-strength ratio.

Alpha-lipoic acid (ALA) as a supplementation for weight loss: results from a meta-analysis of randomized controlled trials.

PubMed

Kucukgoncu, S; Zhou, E; Lucas, K B; Tek, C

2017-05-01

Obesity is associated with significant morbidity and mortality rates. Even modest weight loss may be associated with health benefits. Alpha-lipoic acid (ALA) is a naturally occurring antioxidant. Studies have suggested anti-obesity properties of ALA; however, results are inconsistent. The purpose of this study is to conduct a meta-analysis of the effect of ALA on weight and body mass index (BMI). A comprehensive, systematic literature search identified 10 articles on randomized, double-blind, placebo-controlled studies involving ALA. We conducted a meta-analysis of mean weight and BMI change differences between ALA and placebo treatment groups. Alpha-lipoic acid treatment coincided with a statistically significant 1.27 kg (confidence interval = 0.25 to 2.29) greater mean weight loss compared with the placebo group. A significant overall mean BMI difference of -0.43 kg/ m 2 (confidence interval = -0.82 to -0.03) was found between the ALA and placebo groups. Meta-regression analysis showed no significance in ALA dose on BMI and weight changes. Study duration significantly affected BMI change, but not weight change. Alpha-lipoic acid treatment showed small, yet significant short-term weight loss compared with placebo. Further research is needed to examine the effect of different doses and the long-term benefits of ALA on weight management. © 2017 World Obesity Federation.

(Networking + Integrating) * (Systems + Society). Proceedings of the Annual Canadian Conference of Information Science (12th, Toronto, Ontario, May 14-16, 1984) = (Reseaux + Integration) * (Systemes + Societe). Comptes rendus de la conference annuelle Canadienne des sciences de l'information (12th, Toronto, Ontario, 14-16 mai, 1984).

ERIC Educational Resources Information Center

Canadian Association for Information Science, Ottawa (Ontario).

Seventeen papers from the 1984 annual conference of the Canadian Association for Information Science (CAIS) are presented in four broad topic areas. The first group, which focuses on changing roles in information access, includes the keynote address by Charles Meadow, "Integrating Access to Information Utilities: Promises, Problems, and…

Characterization of the Ala62Pro polymorphic variant of human cytochrome P450 1A1 using recombinant protein expression

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Seung Heon; Kang, Sukmo; Dong, Mi Sook

2015-06-15

Cytochrome P450 (CYP) 1A1 is a heme-containing enzyme involved in detoxification of hydrophobic pollutants. Its Ala62Pro variant has been identified previously. Ala62 is located in α-helix A of CYP1A1. Residues such as Pro and Gly are α-helix breakers. In this study, the Ala62Pro variant was characterized using heterologous expression. E. coli expressing the Ala62Pro variant, and the purified variant protein, had lower CYP (i.e. holoenzyme) contents than their wild-type (WT) equivalents. The CYP variant from E. coli and mammalian cells exhibited lower 7-ethoxyresorufin O-dealkylation (EROD) and benzo[a]pyrene hydroxylation activities than the WT. Enhanced supplementation of a heme precursor during E.more » coli culture did not increase CYP content in E. coli expressing the variant, but did for the WT. As for Ala62Pro, E. coli expressing an Ala62Gly variant had a lower CYP content than the WT counterpart, but substitution of Ala62 with α-helix-compatible residues such as Ser and Val partially recovered the level of CYP produced. Microsomes from mammalian cells expressing Ala62Pro and Ala62Gly variants exhibited lower EROD activities than those expressing the WT or Ala62Val variant. A region harboring α-helix A has interactions with another region containing heme-interacting residues. Site-directed mutagenesis analyses suggest the importance of interactions between the two regions on holoenzyme expression. Together, these findings suggest that the Ala62Pro substitution leads to changes in protein characteristics and function of CYP1A1 via structural disturbance of the region where the residue is located. - Highlights: • Ala62 is located in α-helix A of the carcinogen-metabolizing enzyme CYP1A1. • Pro acts as an α-helix breaker. • A variant protein of CYP1A1, Ala62Pro, had lower heme content than the wild-type. • The variant of CYP1A1 had lower enzyme activities than the wild-type.« less

Balancing Rights: Education Law in a Brave New World. Papers [of the] Education Law Association (ELA) Annual Conference (48th, New Orleans, LA, November 14-16, 2002).

ERIC Educational Resources Information Center

Education Law Association, Dayton, OH.

This collection contains 54 papers from the 48th annual conference of the Education Law Association held in November 2002. It has as its focus education law, yet it covers a wide variety of topics and issues affecting the entire range of education from preschool to college. Among the topics are the following: school vouchers; school safety and…

Research in Science Education, Volume 5. Proceedings of the Annual Conference of the Australian Science Education Research Association (6th, Flinders University, Bedford Park, South Australia, May 19-21, 1975).

ERIC Educational Resources Information Center

Lucas, A. M., Ed.; Power, Colin, N., Ed.

This volume contains papers presented at the sixth Annual Conference of the Australian Science Education Research Association (ASERA) held at Flinders University in May, 1975. Paper topics include: pupil learning and classroom climate, teacher structuring behavior, the Australian Science Education Project (ASEP), cognitive preference and…

Special Issue: European Conference on Surface Science 2014

NASA Astrophysics Data System (ADS)

Opila, Robert L.; Ertas, Gulay

2015-11-01

The present Special Issue of Applied Surface Science is intended to provide a collection of peer-reviewed contributions presented at the Symposium "European Conference on Surface Science" held in Antalya (Turkey), August 31-September 5, 2014. This conference is organized annually through the joint efforts of the Surface Science Division of IUVSTA and the Surface and Interface Section of the European Physical Society (EPS). The ECOSS conference series started in 1978 in Amsterdam, Netherlands, and has been held in various cities throughout Europe during the past years. This is the first time that an ECOSS conference was held in Turkey, with the chairmanship of Prof. Sefik Suzer of Bilkent University, Ankara.

Proceedings: Second Annual Pacific Northwest Alternative and Renewable Energy Resources Conference.

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1980-01-01

Papers presented at the conference are published in this volume. The purpose of the conference was to solicit regional cooperation in the promoting of near-term development of such alternative and renewable energy resources in the Pacific Northwest as: cogeneration; biomass; wind; small hydro; solar end-use applications; and geothermal direct heat utilization. Separate abstracts of selected papers were prepared for inclusion in the Energy Data Base.

Bolden at FAA Commercial Space Transportation Conference

NASA Image and Video Library

2011-02-09

NASA Administrator Charles Bolden speaks at the 14th Annual Federal Aviation Administration (FAA) Commercial Space Transport Conference at the Washington Convention Center on Wednesday, Feb. 9, 2001. Photo Credit: (NASA/Carla Cioffi)

ALA-PDT elicits oxidative damage and apoptosis in UVB-induced premature senescence of human skin fibroblasts.

PubMed

Zhou, Bing-Rong; Zhang, Li-Chao; Permatasari, Felicia; Liu, Juan; Xu, Yang; Luo, Dan

2016-06-01

5-Aminolevulinic acid photodynamic therapy (ALA-PDT) has been used for the treatment of skin photoaging. It can significantly improve the appearance of fine lines, dotted pigmentation, and roughness of photoaged skin. However, the mechanisms by which ALA-PDT yields rejuvenating effects on photoaged skin have not been well elucidated. Thus, in this study we explored the effects of ALA-PDT in photoaged fibroblasts. We established a stress-induced premature senescence (SIPS) model by repeated exposures of human dermal fibroblasts (HDFs) to ultraviolet B (UVB) irradiation. Cells were irradiated by red light laser at 635nm wavelength (50mW/cm(2)). Intracellular protoporphyrin IX (PpIX) was detected by confocal microscopy. Intracellular reactive oxygen species (ROS) level and mitochondrial membrane potential (MMP) change were detected by fluorescence microscopy and flow cytometry. Morphological changes were observed by optical microscopy. Proliferative activity was measured by a cell counting kit-8 (CCK-8). Cell apoptosis was detected by fluorescence microscopy using Hoechst staining and flow cytometry using annexin V/propidium Iodide double staining. Intracellular PpIX fluorescence in UVB-induced premature senescent HDFs (UVB-SIPS-HDFs) reached the highest intensity after incubation with 1.00mmol/L ALA for 6h (P<0.05). Compared with control group, intracellular ROS level, MMP, and apoptotic rate were increased (P<0.05) and proliferative activity was decreased (P<0.05) in UVB-SIPS-HDFs treated with ALA-PDT, which were positively correlated to ALA incubation time and red light laser dose. Our study demonstrated that ALA-PDT elicits oxidative damage and apoptosis in photoaged fibroblasts in vitro, which may be the basis for the rejuvenating effects on photoaged skin. Copyright © 2016 Elsevier B.V. All rights reserved.

Lifelong imbalanced LA/ALA intake impairs emotional and cognitive behavior via changes in brain endocannabinoid system.

PubMed

Zamberletti, Erica; Piscitelli, Fabiana; De Castro, Valentina; Murru, Elisabetta; Gabaglio, Marina; Colucci, Paola; Fanali, Chiara; Prini, Pamela; Bisogno, Tiziana; Maccarrone, Mauro; Campolongo, Patrizia; Banni, Sebastiano; Rubino, Tiziana; Parolaro, Daniela

2017-02-01

Imbalanced dietary n-3 and n-6 PUFA content has been associated with a number of neurological conditions. Endocannabinoids are n-6 PUFA derivatives, whose brain concentrations are sensitive to modifications of fatty acid composition of the diet and play a central role in the regulation of mood and cognition. As such, the endocannabinoid system appears to be an ideal candidate for mediating the effects of dietary fatty acids on mood and cognition. Lifelong administration of isocaloric α-linolenic acid (ALA)-deficient and -enriched diets induced short-term memory deficits, whereas only dietary ALA enrichment altered emotional reactivity in adult male rats compared with animals fed a standard diet that was balanced in ALA/linoleic acid (LA) ratio. In the prefrontal cortex, both diets reduced 2-AG levels and increased MAG lipase expression, whereas only the enriched diet reduced AEA levels, simultaneously increasing FAAH expression. In the hippocampus, an ALA-enriched diet decreased AEA content and NAPE-PLD expression, and reduced 2-AG content while increasing MAG lipase expression. These findings highlight the importance of a diet balanced in fatty acid content for normal brain functions and to support a link between dietary ALA, the brain endocannabinoid system, and behavior, which indicates that dietary ALA intake is a sufficient condition for altering the endocannabinoid system in brain regions modulating mood and cognition. Copyright © 2017 by the American Society for Biochemistry and Molecular Biology, Inc.

RNAi-mediated silencing of hepatic Alas1 effectively prevents and treats the induced acute attacks in acute intermittent porphyria mice.

PubMed

Yasuda, Makiko; Gan, Lin; Chen, Brenden; Kadirvel, Senkottuvelan; Yu, Chunli; Phillips, John D; New, Maria I; Liebow, Abigail; Fitzgerald, Kevin; Querbes, William; Desnick, Robert J

2014-05-27

The acute hepatic porphyrias are inherited disorders of heme biosynthesis characterized by life-threatening acute neurovisceral attacks. Factors that induce the expression of hepatic 5-aminolevulinic acid synthase 1 (ALAS1) result in the accumulation of the neurotoxic porphyrin precursors 5-aminolevulinic acid (ALA) and porphobilinogen (PBG), which recent studies indicate are primarily responsible for the acute attacks. Current treatment of these attacks involves i.v. administration of hemin, but a faster-acting, more effective, and safer therapy is needed. Here, we describe preclinical studies of liver-directed small interfering RNAs (siRNAs) targeting Alas1 (Alas1-siRNAs) in a mouse model of acute intermittent porphyria, the most common acute hepatic porphyria. A single i.v. dose of Alas1-siRNA prevented the phenobarbital-induced biochemical acute attacks for approximately 2 wk. Injection of Alas1-siRNA during an induced acute attack significantly decreased plasma ALA and PBG levels within 8 h, more rapidly and effectively than a single hemin infusion. Alas1-siRNA was well tolerated and a therapeutic dose did not cause hepatic heme deficiency. These studies provide proof-of-concept for the clinical development of RNA interference therapy for the prevention and treatment of the acute attacks of the acute hepatic porphyrias.

Proceedings of the Ninth Annual Summer Conference: NASA/USRA University Advanced Aeronautics Design Program and Advanced Space Design Program

NASA Technical Reports Server (NTRS)

1993-01-01

The NASA/USRA University Advanced Design Program was established in 1984 as an attempt to add more and better design education to primarily undergraduate engineering programs. The original focus of the pilot program encompassing nine universities and five NASA centers was on space design. Two years later, the program was expanded to include aeronautics design with six universities and three NASA centers participating. This year marks the last of a three-year cycle of participation by forty-one universities, eight NASA centers, and one industry participant. The Advanced Space Design Program offers universities an opportunity to plan and design missions and hardware that would be of usc in the future as NASA enters a new era of exploration and discovery, while the Advanced Aeronautics Design Program generally offers opportunities for study of design problems closer to the present time, ranging from small, slow-speed vehicles to large, supersonic and hypersonic passenger transports. The systems approach to the design problem is emphasized in both the space and aeronautics projects. The student teams pursue the chosen problem during their senior year in a one- or two-semester capstone design course and submit a comprehensive written report at the conclusion of the project. Finally, student representatives from each of the universities summarize their work in oral presentations at the Annual Summer Conference, sponsored by one of the NASA centers and attended by the university faculty, NASA and USRA personnel and aerospace industry representatives. As the Advanced Design Program has grown in size, it has also matured in terms of the quality of the student projects. The present volume represents the student work accomplished during the 1992-1993 academic year reported at the Ninth Annual Summer Conference hosted by NASA Lyndon B. Johnson Space Center, June 14-18, 1993.

WEST; Report of the Second Annual Conference, February 28-March 2, 1972.

ERIC Educational Resources Information Center

Elliott, Richard B., Comp.

The 1972 WEST conference report represents a cooperative project of the Western Educational Society for Telecommunications and the ERIC Clearinghouse on Media and Technology. The conference featured discussions of public television, instructional television, cable television, national educational radio, and national public radio, educational…

DEVELOP students attend conference

NASA Image and Video Library

2009-06-08

Last month, Madeline Brozen and Jason Jones of the DEVELOP Program at John C. Stennis Space Center joined members from the program's national office at Langley Research Center to attend the Southern Growth Policies Board annual conference in Biloxi. Pictured are (l to r): Karen Allsbrook, Jonathan Gleason, Gov. Haley Barbour, Madeline Brozen, Lindsay Rogers and Tracey Silcox.

Collective Bargaining and Accountability in Higher Education: A Report Card. Proceedings of the Annual Conference of the National Center for the Study of Collective Bargaining in Higher Education and the Professions (27th, New York, NY, April 19-20, 1999).

ERIC Educational Resources Information Center

Naples, Caesar J., Ed.

Following an introduction, listing of the program for the Twenty-Seventh Annual Conference, and description of the Center, this conference proceedings contains the following papers: (1) "Some Thoughts and Facts on CUNY, Public Higher Education in New York State, and Accountability" (Augusta Souza Kappner); (2) "Academic Politics and Academic…

Sailing into the New Millennium: Charting the Course for Institutional Research. North East Association for Institutional Research Annual Conference Proceedings (26th, Newport, Rhode Island, November 13-16, 1999).

ERIC Educational Resources Information Center

North East Association for Institutional Research.

This proceedings contains papers from the 1999 annual conference of the North East Association for Institutional Research. The papers are: (1) "A Marketing Research Program for Commuter Colleges" (Michelle S. Appel and Craig A. Clagett); (2) "Where Do I Start? Determining Institutional Information Needs beyond Mandated Reporting" (Michelle S.…

Highlights from the 6th International Society for Computational Biology Student Council Symposium at the 18th Annual International Conference on Intelligent Systems for Molecular Biology

PubMed Central

2010-01-01

This meeting report gives an overview of the keynote lectures and a selection of the student oral and poster presentations at the 6th International Society for Computational Biology Student Council Symposium that was held as a precursor event to the annual international conference on Intelligent Systems for Molecular Biology (ISMB). The symposium was held in Boston, MA, USA on July 9th, 2010.

Desleucyl-Oritavancin with a Damaged d-Ala-d-Ala Binding Site Inhibits the Transpeptidation Step of Cell-Wall Biosynthesis in Whole Cells of Staphylococcus aureus.

PubMed

Kim, Sung Joon; Singh, Manmilan; Sharif, Shasad; Schaefer, Jacob

2017-03-14

We have used solid-state nuclear magnetic resonance to characterize the exact nature of the dual mode of action of oritavancin in preventing cell-wall assembly in Staphylococcus aureus. Measurements performed on whole cells labeled selectively in vivo have established that des-N-methylleucyl-N-4-(4-fluorophenyl)benzyl-chloroeremomycin, an Edman degradation product of [ 19 F]oritavancin, which has a damaged d-Ala-d-Ala binding aglycon, is a potent inhibitor of the transpeptidase activity of cell-wall biosynthesis. The desleucyl drug binds to partially cross-linked peptidoglycan by a cleft formed between the drug aglycon and its biphenyl hydrophobic side chain. This type of binding site is present in other oritavancin-like glycopeptides, which suggests that for these drugs a similar transpeptidase inhibition occurs.

Conference in Rhetorical Criticism. Address of the Annual Conference and Commended Papers (17th, Hayward, California, May 7, 1982).

ERIC Educational Resources Information Center

Ianniello, Raphaella A., Ed.

The four papers in this compilation were drawn from a conference designed to encourage scholars to continue the rhetorical tradition. The first paper, by Robert S. Cathcart, was the opening address of the conference and discusses the "technologization" of rhetoric. Specifically, the paper discusses the application of rhetorical analysis…

Impact of the Pro12Ala polymorphism of the PPARγ2 gene on diabetes and obesity in a highly consanguineous population

PubMed Central

Bener, Abdulbari; Zirie, M; Al-Hamaq, AOAA; Nawaz, Z; Samson, N; Mohammad, R

2015-01-01

Background: The peroxisome proliferator-activated receptors (PPARs) are members of the nuclear hormone receptor subfamily of transcription factors. It has been reported that they play important roles in obesity and the development of type 2 diabetes mellitus (T2DM). Materials and Methods: This case-control study was carried out among 764 Qatari patients with diabetes and 764 healthy subjects above 20 years of age at Primary Healthcare Clinics (PHCs) from January 2011 to December 2012. Face-to-face interviews were based on a questionnaire that included variables such as age, sex, sociodemographic status, body mass index (BMI) and other clinical parameters. The Pro12Ala in the PPARγ2 gene was detected on the LightCycler using two specific probes. Univariate and multivariate statistical analysis were performed. Results: The study revealed that in the diabetes group, Pro/(10.2% vs 9.4%; P = 0.606) and Ala/Ala (1.4% vs 0.9%; P = 0.343) were higher than in controls, whereas Pro/Pro (88.4% vs 89.7%;P = 0.413) was lower in diabetes patients, but no significant difference was observed among the genotype groups. In obese patients with diabetes, Pro/Pro (89% vs 89.9%;P = 0.792) and Pro/Ala (8.9% vs 10.1%;P = 0.671) were lower than in obese healthy subjects. No homozygous Ala/Ala was found in obese healthy subjects, whereas 6 Ala/Ala homozygotes were in obese diabetes group. But in diabetes group, obese patients had higher homozygous of Pro/Pro (89.3% vs 87.8%;P = 0.523) and Ala/Ala (1.8% vs 1.2%;P = 0.771) compared to non-obese patients. Conclusion: The current study did not reveal an association between the Pro12Ala polymorphism of the PPAR γ2 gene and type 2 diabetes (T2D) in Qatari's population. PMID:25593831

ALA PDT for high grade dysplasia in Barrett's oesophagus: review of a decade's experience

NASA Astrophysics Data System (ADS)

Bown, Stephen G.; Mackenzie, Gary D.; Dunn, Jason M.; Thorpe, Sally M.; Lovat, Laurence B.

2009-06-01

We have been investigating PDT with 5 aminolaevulinic acid (ALA) for the treatment of high grade dysplasia (HGD) in Barrett's oesophagus (BO) for over a decade. This drug has inherent advantages over porfimer sodium (Photofrin), the current approved photosensitiser in the UK and USA, which causes strictures in 18-50% and light sensitivity for up to three months. ALA has a lower rate of oesophageal strictures due to its preferential activity in the mucosa, sparing the underlying muscle, and patients are only light sensitive for 1-2 days. Within a randomised controlled trial, we demonstrated that an ALA dose of 60mg/kg activated by 1000J/cm red laser light is the most effective. Using these values we achieved complete reversal of HGD at 1 year in 89% of 27 patients. A randomised controlled trial of ALA vs porfimer sodium PDT for HGD is currently under way with end points of efficacy and safety. 50 of 66 patients have been recruited. Preliminary data suggest ALA PDT is safer with a trend to higher efficacy. Late relapse can occur in 20% of patients. New prognostic markers, in particular aneuploidy, are helping us to identify and target patients at risk of late relapse. Furthermore optical biopsy techniques such as elastic scattering spectroscopy (ESS) may allow detection of nuclear abnormalities in vivo and enable us to target areas of interest whilst reducing sampling error. PDT faces new challenges for the treatment of HGD in BO, with the recent introduction of balloon based radiofrequency ablation. This technique appears simpler and as effective as PDT, but follow up is currently short and long term safety data is lacking. In our experience ALA PDT is currently the most effective minimally invasive treatment for HGD in BO. This work was undertaken at UCLH/UCL who received a proportion of funding from the Department of Health's NIHR Biomedical Research Centres funding scheme.

"High/Scope Supporting the Child, the Family, the Community": A Report of the Proceedings of the High/Scope Ireland Third Annual Conference, 12th October 2004, Newry, Northern Ireland

ERIC Educational Resources Information Center

Peyton, Lynne

2005-01-01

The third annual High/Scope Ireland Conference provided a forum for speakers workshop leaders and delegates from across Ireland, the UK, USA, Europe and South Africa to share their experiences of High/Scope in action. Research demonstrates that long term benefits for High/Scope participants include increased literacy rates, school success and…

ALA 2010 Midwinter Meeting: The Price to Participate

ERIC Educational Resources Information Center

Berry, John N., III

2009-01-01

While the library economy continues its downward slide, the cost of attending the American Library Association (ALA) Midwinter Meeting seems as high as ever. That is the price of professional participation. These days it seems a bit too high and tends to limit involvement in the old association to librarians in the higher echelons of the field.…

Thermally activated persistent photoconductivity & donor binding energy in high mobility AlAs QWs

NASA Astrophysics Data System (ADS)

Dasgupta, S.; Knaak, C.; Fontcuberta, A.; Bichler, M.; Abstreiter, G.; Grayson, M.

2008-03-01

In AlAs, valley index is important quantum number which can help understand interactions. However, important parameters for growth such as donor binding energy and Si δ-doping efficiency were unknown and AlAs quantum wells (QWs) typically did not conduct in dark. We grew series of (001) and (110) oriented double-sided doped n-type AlAs QWs and deduced Si donor binding energy δ in Al0.45Ga0.55 As and doping efficiency η. They work in dark possibly because dilute charge traps in substrate are screened by backside doping. From dark saturation density for doping series we deduced δdk=65.2 meV [1]. Our studies show thermally activated PPC where sample is illuminated at 4 K and returned to dark without appreciable density increase. As temperature is increased to 30 K, density doubles, indicating shallow binding energy δPIA=0 meV post-illumination anneal (PIA). Doping efficiency after illumination for (001) facet was found to be η=n2D/nSi=35% and for (110) η=17%. With this understanding, we designed (001) AlAs QW with PIA density n=2.4 x 10^11 cm-2 and mobility μ=4.3 x 10^5 cm^2/Vs(330 mK), improvement of almost an order of magnitude over published results. [1] Dasgupta, et al. APL (2007)

Modulatory effects of alpha-lipoic acid (ALA) administration on insulin sensitivity in obese PCOS patients.

PubMed

Genazzani, A D; Shefer, K; Della Casa, D; Prati, A; Napolitano, A; Manzo, A; Despini, G; Simoncini, T

2018-05-01

To evaluate the efficacy of alpha-lipoic acid (ALA) administration on hormonal and metabolic parameters of obese PCOS patients. A group of 32 obese PCOS patients were selected after informed consent. 20 patients referred to have first grade relatives with diabetes type I or II. Hormonal and metabolic parameters as well as OGTT were evaluated before and after 12 weeks of ALA integrative administration (400 mg per os every day). ALA administration significantly decreased insulin, glucose, BMI and HOMA index. Hyperinsulinemia and insulin response to OGTT decreased both as maximal response (Δmax) and as AUC. PCOS with diabetes relatives showed the decrease also of triglyceride and GOT. Interestingly in all PCOS no changes occurred on all hormonal parameters involved in reproduction such as LH, FSH, and androstenedione. ALA integrative administration at a low dosage as 400 mg daily improved the metabolic impairment of all PCOS patients especially in those PCOS with familiar diabetes who have a higher grade of risk of NAFLD and predisposition to diabetes.

A Rhetorical Criticism Conference as an Instructional Strategy for the Undergraduate Student.

ERIC Educational Resources Information Center

Gabbard-Alley, Anne

1982-01-01

To demonstrate that rhetoric can be useful and challenging, a course in rhetorical criticism was designed with a public conference as a major component. This article describes and evaluates the first annual James Madison University Rhetorical Criticism Conference, April 2-3, 1981. (PD)

Proteomics and SSH Analyses of ALA-Promoted Fruit Coloration and Evidence for the Involvement of a MADS-Box Gene, MdMADS1

PubMed Central

Feng, Xinxin; An, Yuyan; Zheng, Jie; Sun, Miao; Wang, Liangju

2016-01-01

Skin color is a key quality attribute of fruits and how to improve fruit coloration has long been a major concern. 5-Aminolevulinic acid (ALA), a natural plant growth regulator, can significantly increase anthocyanin accumulation in fruit skin and therefore effectively improve coloration of many fruits, including apple. However, the molecular mechanism how ALA stimulates anthocyanin accumulation in fruit skin remains unknown. Here, we investigated the impact of ALA on apple skin at the protein and mRNA levels. A total of 85 differentially expressed proteins in apple skins between ALA and water treatment (control) were identified by complementary gel-based and gel-free separation techniques. Most of these differentially expressed proteins were up-regulated by ALA. Function analysis suggested that 87.06% of the ALA-responsive proteins were associated with fruit ripening. To further screen ALA-responsive regulators, we constructed a subtracted cDNA library (tester: ALA treatment; driver: control) and obtained 104 differentially expressed unigenes, of which 38 unigenes were indicators for the fruit ripening-related genes. The differentially changed proteins and transcripts did not correspond well at an individual level, but showed similar regulated direction in function at the pathway level. Among the identified fruit ripening-related genes, the expression of MdMADS1, a developmental transcription regulator of fruit ripening, was positively correlated with expression of anthocyanin biosynthetic genes (MdCHS, MdDFR, MdLDOX, and MdUFGT) in apple skin under ALA treatment. Moreover, overexpression of MdMADS1 enhanced anthocyanin content in transformed apple calli, which was further enhanced by ALA. The anthocyanin content in MdMADS1-silenced calli was less than that in the control with ALA treatment, but higher than that without ALA treatment. These results indicated that MdMADS1 is involved in ALA-induced anthocyanin accumulation. In addition, anthocyanin

Improvements in glucose homeostasis in response to regular exercise are influenced by the PPARG Pro12Ala variant: results from the HERITAGE Family Study.

PubMed

Ruchat, S-M; Rankinen, T; Weisnagel, S J; Rice, T; Rao, D C; Bergman, R N; Bouchard, C; Pérusse, L

2010-04-01

Exercise training improves glucose homeostasis, but large inter-individual differences are reported, suggesting a role of genetic factors. We investigated whether variants either confirmed or newly identified as diabetes susceptibility variants through genome-wide association studies (GWAS) modulate changes in phenotypes derived from an IVGTT in response to an endurance training programme. We analysed eight polymorphisms in seven type 2 diabetes genes (CDKAL1 rs7756992; CDKN2A and CDKN2B rs10811661 and rs564398; HHEX rs7923837; IGF2BP2 rs4402960; KCNJ11 rs5215; PPARG rs1801282; and TCF7L2 rs7903146) in a maximum of 481 sedentary, non-diabetic white individuals, who participated in a 20-week endurance training programme. Associations were tested between the variants and changes in IVGTT-derived phenotypes. The only evidence of association with training response was found with PPARG rs1801282 (Pro12Ala). We observed that Ala carriers experienced greater increase in overall glucose tolerance (Deltaglucose disappearance index Ala/Ala 0.22 +/- 0.22, Pro/Ala 0.14 +/- 0.06, Pro/Pro 0.004 +/- 0.03; p = 0.0008), glucose effectiveness (Ala/Ala 0.28 +/- 0.41, Pro/Ala 0.44 +/- 0.14, Pro/Pro 0.09 +/- 0.06; p = 0.004), acute insulin response to glucose (Ala/Ala 64.21 +/- 37.73, Pro/Ala -11.92 +/- 40.30, Pro/Pro -46.30 +/- 14.70; p = 0.03) and disposition index (Ala/Ala 551.8 +/- 448.5, Pro/Ala 534.6 +/- 218.3, Pro/Pro -7.44 +/- 88.18; p = 0.003). Compared with Pro/Pro individuals, PPARG Ala carriers experienced greater improvements in glucose and insulin metabolism in response to regular endurance training. However, we did not find evidence of association between type 2 diabetes susceptibility variants recently identified through GWAS and glucose homeostasis response to exercise. Our results extend those of previous studies showing that Ala carriers appear to be more responsive to beneficial health effects of lifestyle interventions.

Student Learning and Conference Design: The Case of Interdisciplinary/Multidisciplinary Woolf

ERIC Educational Resources Information Center

Martin, Ann; Holland, Kathryn; Witiw, Taylor

2015-01-01

Academic conferences are events geared to disciplinary specialization, and much of the SoTL literature regarding scholarly gatherings addresses their benefits for graduate student apprenticeship. In our organization of the 22nd Annual International Conference on Virginia Woolf, we explored other forms of pedagogy to augment an academic…

[Selected Papers of the EDUCOM Annual Conference, October 1981].

ERIC Educational Resources Information Center

Interuniversity Communications Council (EDUCOM), Princeton, NJ.

This collection of 10 papers from the 1981 conference of the Interuniversity Communications Council (EDUCOM) highlights developments in new communications technologies and their impact on higher education, emphasizing computer usage and telecommunications advancements. Three papers analyzing computer applications to higher education focus on the…

The Fifth Annual Pennsylvania Conference on Postsecondary Occupational Education.

ERIC Educational Resources Information Center

Gillie, Angelo C., Ed.

The document contains the full text of the following conference papers: Introduction: Cooperative Ventures in Vocational Education: Pennsylvania Style, by Angelo C. Gillie, Sr.; Cooperation and Coordination Among Secondary and Postsecondary Vocational Education: The Massachusetts Story, Charles H. Buzzell and Vincent P. Lamo; Cooperation and…

International Conference on Intelligent Systems for Molecular Biology (ISMB)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldberg, Debra; Hibbs, Matthew; Kall, Lukas

The Intelligent Systems for Molecular Biology (ISMB) conference has provided a general forum for disseminating the latest developments in bioinformatics on an annual basis for the past 13 years. ISMB is a multidisciplinary conference that brings together scientists from computer science, molecular biology, mathematics and statistics. The goal of the ISMB meeting is to bring together biologists and computational scientists in a focus on actual biological problems, i.e., not simply theoretical calculations. The combined focus on "intelligent systems" and actual biological data makes ISMB a unique and highly important meeting, and 13 years of experience in holding the conference hasmore » resulted in a consistently well organized, well attended, and highly respected annual conference. The ISMB 2005 meeting was held June 25-29, 2005 at the Renaissance Center in Detroit, Michigan. The meeting attracted over 1,730 attendees. The science presented was exceptional, and in the course of the five-day meeting, 56 scientific papers, 710 posters, 47 Oral Abstracts, 76 Software demonstrations, and 14 tutorials were presented. The attendees represented a broad spectrum of backgrounds with 7% from commercial companies, over 28% qualifying for student registration, and 41 countries were represented at the conference, emphasizing its important international aspect. The ISMB conference is especially important because the cultures of computer science and biology are so disparate. ISMB, as a full-scale technical conference with refereed proceedings that have been indexed by both MEDLINE and Current Contents since 1996, bridges this cultural gap.« less

Accumulation of polyubiquitylated proteins in response to Ala-Ala-Phe-chloromethylketone is independent of the inhibition of Tripeptidyl peptidase II.

PubMed

Villasevil, Eugenia M; Guil, Sara; López-Ferreras, Lorena; Sánchez, Carlos; Del Val, Margarita; Antón, Luis C

2010-09-01

In the present study we have addressed the issue of proteasome independent cytosolic protein degradation. Tripeptidyl peptidase II (TPPII) has been suggested to compensate for a reduced proteasome activity, partly based on evidence using the inhibitor Ala-Ala-Phe-chloromethylketone (AAF-cmk). Here we show that AAF-cmk induces the formation of polyubiquitin-containing accumulations in osteosarcoma and Burkitt's lymphoma cell lines. These accumulations meet many of the landmarks of the aggresomes that form after proteasome inhibition. Using a combination of experiments with chemical inhibitors and interference of gene expression, we show that TPPII inhibition is not responsible for these accumulations. Our evidence suggests that the relevant target(s) is/are in the ubiquitin-proteasome pathway, most likely upstream the proteasome. We obtained evidence supporting this model by inhibition of Hsp90, which also acts upstream the proteasome. Although our data suggest that Hsp90 is not a target of AAF-cmk, its inhibition resulted in accumulations similar to those obtained with AAF-cmk. Therefore, our results question the proposed role for TPPII as a prominent alternative to the proteasome in cellular proteolysis. Copyright 2010 Elsevier B.V. All rights reserved.

Expanding Reading Interest, Response, Achievement; Proceedings of the Annual Conference of the North Carolina Council of the International Reading Association (7th, Greensboro, North Carolina, March 13-14, 1975).

ERIC Educational Resources Information Center

Culyer, Richard C., III, Ed.

This volume presents papers given at the Seventh Annual Conference on Reading of the North Carolina Council of the International Reading Association. General-session addresses include "Reading: The Fassport to the 80s" by Lewis C. Dowdy, "Developing the Habit of Reading Success" by William K. Durr, "Neither Simple-Minded nor Muddle-Headed Be" by…

Laser-induced fluorescence diagnostics of basal cell carcinomas of the skin following topical ALA application

NASA Astrophysics Data System (ADS)

af Klinteberg, Claes; Nilsson, Annika M.; Wang-Nordman, Ingrid; Andersson-Engels, Stefan; Svanberg, Sune; Svanberg, Katarina

1996-12-01

Fourteen patients with superficial basal cell carcinomas (BCCs) and fifteen patients with nodular BCCs were investigated by means of laser-induced fluorescence (LIF) in connection with photodynamic therapy (PDT). Topical application of (delta) -amino levulinic acid (ALA) was performed six hours prior to the treatment session. Fluorescence spectra were recorded, using a point-monitoring system with an excitation wavelength of 405 nm. The measurements were performed in scans over the lesion and the surrounding normal skin before application of ALA, and immediately before and after the laser treatment. The selective uptake of the photosensitive resulted in a fluorescence intensity ratio of 2.4:1 for superficial BCCs and 2.5:1 for nodular BCCs. If the fluorescence intensity was divided by the autofluorescence, this resulted in a contrast enhancement of about a factor 6 for tumor tissue. In seven patients (five with nodular BCC and two with superficial BCC), additional fluorescence measurements were performed two and four hours following the ALA application, and two hours after the PDT procedure. Thus, the kinetics of the transformation of ALA to protoporphyrin IX (PpIX) could be followed, which indicated that the synthesis of PpIX was more rapid in the tumor than in the normal tissue. After four hours, the PpIX level inside the tumour was saturated, while there still was an accumulation in the surrounding skin. The highest contrast between tumor and normal skin was reached within two hours after the ALA application.

Columbine Author Speaks at Conference

ERIC Educational Resources Information Center

Cook, Andrea J.

2004-01-01

Brooks Brown, the author of No Easy Answers: The Truth Behind Death at Columbine High School, spoke at the 11th annual Reclaiming Youth International No Disposable Kids conference at Rushmore Plaza Holiday Inn. Brown, who worked with Michael Moore on his Academy Award winning documentary, "Bowling for Columbine," said the letters he…

The Conference Board and Education: A Long Standing Commitment. Annual Report 1989.

ERIC Educational Resources Information Center

Conference Board, Inc., New York, NY.

Since its founding in 1916, the goals of the Conference Board have been to improve the business enterprise system and to enhance the contribution of business to society. To accomplish this, the Conference Board sponsors forums and research to identify areas of concern and to stimulate the exchange of ideas among leading industry executives. The…

Editorial: Conference Comments by the General Chair

NASA Astrophysics Data System (ADS)

LaBel, Ken

2012-12-01

An overview is presented of the 49th Annual International Nuclear and Space Radiation Effects Conference (NSREC), held July 16-20, 2012 at the InterContinental Hotel in downtown Miami, Florida, USA. The 2012 Conference followed previous editions as an international radiation effects on electronics, materials, and systems showcase. The conference was sponsored by the Radiation Effects Committee of the IEEE Nuclear and Plasma Sciences Society. In addition, NSREC was supported by a cadre of government agencies and industry members. The 2012 edition of the conference was attended by 607 members of the radiation effects community. Of this number, 118 non-US attendees participated from 20 different countries with particularly strong attendance from France, United Kingdom, Japan, Canada, and Germany. Total attendance including exhibitors and guests was 802 people.

P12.105-ALA GUIDED REMOVAL AND COMBINED TREATMENT IN MALIGNANT GLIOMA

PubMed Central

Oppido, P.A.; Carapella, C.M.; Pompili, A.; Vidiri, A.; Pace, A.; Villani, V.

2014-01-01

INTRODUCTION: Malignant gliomas are the most unfavourable brain tumours. Recent evidence suggests that extensive tumour removal is associated with better survival. The current treatment is complete as possible resection of the contrast-enhancing tumour tissue, followed by adjuvant treatment with radiotherapy and chemotherapy. As it appears difficult to distinguish between infiltration tumour and normal tissue, specially in recurrent tumours, the radical removal becomes harmful. Techniques to visualize the borderline tumour intraoperatively are helpful. More recently, fluorescence guidance has taken advantage of intrinsic metabolic and structural changes that occur within malignant glioma by exploiting the eme biosynthetic pathway and a natural biochemical in that pathway, 5-aminolevulinic acid (5-ALA). METHODS: Since the end of 2009, in our Institute 54 patients were operated on using fluorescence guided tumour resection. Preoperatively, all enrolled patients had MRI showing contrast enhancing lesions. MRI within 72 hours after surgery and thereafter at 3-month interval was performed. 32 patients were newly diagnosed tumour, 22 were recurrent malignant glioma. An oral dose of 20 mg 5-ALA /kg body weight was administered to each patient. By a NC4 OPMI Pentero operating microscope (Zeiss), enabled switching from xenon light to violet-blue light for visualizing fluorescence, the surgical resection was performed. Histology was in 48 glioblastoma (1 gliosarcoma), in 4 anaplastic oligodendroglioma, in 1 oligodendroglioma I WHO and in 1 pleomorphic xanthoastrocytoma. All the patients, as first line treatment, were submitted to radiotherapy and chemotherapy; in recurrent tumours second and in some cases third line treatments were administered. The follow-up ranged from 2 years to 8 months. RESULTS: In all cases the yellow fluorescence due to 5-ALA in cortical vessels was seen. In 47 glioblastoma, 4 anaplastic oligodendroglioma and 1 xanthoastrocytoma the tumour tissue

Twenty-Second Annual NASA Supply and Equipment Management Conference

NASA Technical Reports Server (NTRS)

1989-01-01

The status of actions from the 1988 conference is reviewed. Environmental safety issues, definitions, and regulations; contract transition, payload logistics transition, and safety and support equipment; supply products and services, bar code technology, and inventory accuracy; equipment management workshop topics; and contract property workshop topics are outlined.

PREFACE: Annual Conference on Functional Materials and Nanotechnologies - FM&NT 2011

NASA Astrophysics Data System (ADS)

Sternberg, Andris; Muzikante, Inta; Zicans, Janis

2011-06-01

The International Conference Functional Materials and Nanotechnologies (FM&NT-2011) was held in Riga, 5-8 April 2011 in the Institute of Solid State Physics, University of Latvia (ISSP LU). The conference was organized in co-operation with projects ERANET 'MATERA' and National Research programme in Materials Science and Information Technologies. The purpose of the conference was to bring together scientists, engineers and students from universities, research institutes and related industrial companies active in the field of advanced material science and materials technologies trends and future activities. Scientific themes covered in the conference are: theoretical research and modelling of processes and materials; materials for energetics, renewable energy technologies and phtovoltaics; multifunctional inorganic, organic and hybrid materials for photonic, micro and nanoelectronic applications and innovative methods for research of nanostructures; advanced technologies for synthesis and research of nanostructured materials, nanoparticles, thin films and coatings; application of innovative materials in science and economics. The number of registered participants from 17 countries was nearly 300. During three days of the conference 22 invited, 69 oral reports and 163 posters were presented. 40 papers, based on these reports, are included in this volume of IOP Conference Series: Materials Science and Engineering. Additional information about FM&NT-2011 is available in its homepage http://www.fmnt.lu.lv. The Organizing Committee would like to thank all speakers, contributors, session chairs, referees and meeting staff for their efforts in making the FM&NT-2011 successful. The Organizing Committee sincerely hopes that that the conference gave all participants new insights into the widespread development of functional materials and nanotechnologies and would enhance the circulation of information released at the meeting. Andris Sternberg Inta Muzikante Janis Zicans

The 1994 Goddard Conference on Space Applications of Artificial Intelligence

NASA Technical Reports Server (NTRS)

Hostetter, Carl F. (Editor)

1994-01-01

This publication comprises the papers presented at the 1994 Goddard Conference on Space Applications of Artificial Intelligence held at the NASA/GSFC, Greenbelt, Maryland, on 10-12 May 1994. The purpose of this annual conference is to provide a forum in which current research and development directed at space applications of artificial intelligence can be presented and discussed.

It Can Be Done: With Advocacy, Libraries Can Thrive on Pacific Islands. Selected Papers from PIALA 2007, Pacific Islands Association of Libraries, Archives and Museums Annual Conference (17th, Tinian and Saipan, Commonwealth of the Northern Mariana Islands, November 12-17, 2007)

ERIC Educational Resources Information Center

Horie, Ruth H., Ed.

2010-01-01

This publication follows the tradition of publishing selected papers from Pacific Islands Association of Libraries, Archives and Museums (PIALA) annual conferences. The volume begins with a listing of the members of the PIALA 2007 Planning Committee, the Officers and Executive Board, and Acknowledgements, followed by the Pre-Conference Workshop…

Highlights from the 2017 North American Cystic Fibrosis Conference.

PubMed

Martiniano, Stacey L; Toprak, Demet; Ong, Thida; Zemanick, Edith T; Daines, Cori L; Muhlebach, Marianne S; Esther, Charles R; Dellon, Elisabeth P

2018-04-16

The 31st annual North American Cystic Fibrosis Conference (NACFC) was held in Indianapolis, IN on November 2-4, 2017. Abstracts of presentations from the conference were published in a supplement to Pediatric Pulmonology [2017; Pediatr Pulmonol Suppl. 52: S1-S776]. The current review summarizes several major topic areas addressed at the conference: the pathophysiology and basic science of cystic fibrosis (CF) lung disease, clinical trials, clinical management issues, and quality improvement (QI). In this review, we describe emerging concepts in several areas of CF research and care. © 2018 Wiley Periodicals, Inc.

Antibody engineering and therapeutics conference. The annual meeting of the antibody society, Huntington Beach, CA, December 7-11, 2014.

PubMed

Larrick, James W; Parren, Paul W H I; Huston, James S; Plückthun, Andreas; Bradbury, Andrew; Tomlinson, Ian M; Chester, Kerry A; Burton, Dennis R; Adams, Gregory P; Weiner, Louis M; Scott, Jamie K; Alfenito, Mark R; Veldman, Trudi; Reichert, Janice M

2014-01-01

The 25th anniversary of the Antibody Engineering & Therapeutics Conference, the Annual Meeting of The Antibody Society, will be held in Huntington Beach, CA, December 7-11, 2014. Organized by IBC Life Sciences, the event will celebrate past successes, educate participants on current activities and offer a vision of future progress in the field. Keynote addresses will be given by academic and industry experts Douglas Lauffenburger (Massachusetts Institute of Technology), Ira Pastan (National Cancer Institute), James Wells (University of California, San Francisco), Ian Tomlinson (GlaxoSmithKline) and Anthony Rees (Rees Consulting AB and Emeritus Professor, University of Bath). These speakers will provide updates of their work, placed in the context of the substantial growth of the industry over the past 25 years.

The time that comes toward us: The Alba Iulia death conferences.

PubMed

Rotar, Marius

2017-01-01

This article illuminates the history of the annual death conference in Alba Iulia, Romania (2007-2015), the only conference on death and dying organized in Eastern Europe. Written by the conference founder, the article tries to set out the main lines of its development over that period. Emphasis is laid on the difficulties of expanding death studies in Romania, the reaction of the wider public to the death conference, and the collaboration beyond borders between death scholars. The articles included in this issue of Death Studies are briefly presented.

A new optical intra-tissue fiber irradiation ALA-PDT in the treatment of acne vulgaris in rabbit model: improved safety and tolerability.

PubMed

Wang, Qian; Jiang, Can; Liu, Wei; Chen, Jin; Lin, Xinyu; Huang, Xiangning; Duan, Xiling

2017-01-01

Photodynamic therapy with topical aminolevulinic acid (ALA-PDT) has been suggested to be effective in treatment of acne vulgaris. However, adverse events occur during and after treatment. To compare the efficacy and tolerability of optical intra-tissue fiber irradiation (OFI) ALA-PDT versus traditional ALA-PDT in treatment of acne vulgaris in rabbit models. Twenty-five rabbits of clean grade were used. Twenty rabbits were randomly selected to establish acne model and the other five were used as control. Rabbits in model group (40 ears) were further divided into four groups (10 ears/group): I, OFI-ALA-PDT with the head of optical fiber inserted into the target lesion (intra-tissue); II, traditional ALA-PDT group; III, OFI group; IV, blank control group without any treatment. Uncomfortable symptoms, adverse events, and effectiveness rates were recorded on post-treatment day 14, 30, and 45. On post-treatment day 14, the effectiveness rate in OFI-ALA-PDT group was obviously higher than that of the other three groups (P<0.05). However, no improved effects were observed in OFI-ALA-PDT group on day 30 and 45. During the period of treatment, the frequencies of uncomfortable symptoms in ALA-PDT group were obviously higher than those in the other three groups (P<0.05). The adverse event rate in OFI-ALA-PDT group was obviously lower than that of the ALA-PDT group (P<0.05). The unblindness of the study and temporary animal models of acne induced may hamper the assessment and monitoring of the results, and future studies are still needed to clarify it further. The OFI-ALA-PDT group (intra-tissue irradiation) showed no improved efficacy on treating rabbit ear acne but had higher safety and better tolerability.

International Federation of Library Associations Annual Conference Papers. Collections and Services Division: Interlending, Rare and Precious Books, and Exchange and Acquisition Sections (47th, Leipzig, East Germany, August 17-22, 1981).

ERIC Educational Resources Information Center

Line, Maurice B.; And Others

This set of papers presented to the Collections and Services Division of the International Federation of Library Associations at its 47th annual conference (1981) includes: "Planning Interlending Systems in Developing Countries," by Maurice B. Line; "Problems of Centralisation of Inter-Library Lending in a De-Centralized Library…

Prevalence of the Pro12Ala missense mutation in the PPARG2 gene in Kuwaiti patients with primary knee osteoarthritis

PubMed Central

Al-Jarallah, Khaled F.; Shehab, Diaa K.; Haider, Mohammad Z.

2011-01-01

BACKGROUND AND OBJECTIVES: Peroxisome proliferator–activated receptors (PPARs) play an important role in a number of cellular and metabolic functions. This study was carried out to determine the prevalence of a missense mutation (Pro12Ala) in the PPARG2 gene in Kuwaiti Arab patients with primary knee osteoarthritis (OA) and healthy controls with the aim of identifying a possible association. DESIGN AND SETTING: A prospective cross-sectional study carried out at three major teaching hospitals (referral centers) in the country over a one-year period. PATIENTS AND METHODS: The prevalence of PPARG2 gene Pro12Ala missense mutation was determined in 104 Kuwaiti Arab patients with primary knee OA and 111 ethnically matched healthy controls. The prevalence of this Pro12Ala missense mutation was also determined in clinical subgroups of OA patients divided on the basis of age at onset, function and radiologic grading. RESULTS The Pro-Pro genotype of the PPARG2 gene Pro12Ala missense mutation was detected in 95/104 (91.3%) cases compared to 111/111 (100%) in the control subjects. The heterozygous Pro-Ala genotype was detected in 9/104 (8.7%) of the OA patients, while it was not detected in any of the controls. The Ala-Ala genotype was not detected in any of the OA patients or the controls. No significant differences were detected in the PPARG2 gene Pro12Ala genotypes in the subgroups of patients classified on the basis of age at onset, functional assessment using Lequesne’s functional index, and radiological grading using Kellgren-Lawrence (K-L) grading. CONCLUSIONS This study found no significant association between the PPARG2 gene Pro12Ala missense mutation and knee OA. However, the presence of the Pro-Pro genotype of the PPARG2 gene mutation has a protective effect against development of OA. PMID:21245597

Tenth AMS Conference on Satellite Meteorology and Oceanography

NASA Technical Reports Server (NTRS)

Ferraro, R.; Colton, M.; Deblonde, G.; Jedlovec, G.; Lee, T.

2000-01-01

The American Meteorological Society held its Tenth Conference on Satellite Meteorology and Oceanography in conjunction with the 80th Annual Meeting in Long Beach, California. For the second consecutive conference, a format that consisted of primarily posters, complemented by invited theme oriented oral presentations, and panel discussions on various aspects on satellite remote sensing were utilized. Joint sessions were held with the Second Conference on Artificial Intelligence, the Eleventh Conference on Middle Atmosphere, and the Eleventh symposium on Global Change Studies. In total, there were 23 oral presentations, 170 poster presentations, and four panel discussions. Over 450 people representing a wide spectrum of the society attended one or more of the sessions in the five-day meeting. The program for the Tenth Conference on Satellite Meteorology and Oceanography can viewed in the October 1999 issue of the Bulletin.

52nd Yearbook of the National Reading Conference (Miami, Florida, December 4-7, 2002)

ERIC Educational Resources Information Center

Fairbanks, Colleen M., Ed.; Worthy, Jo, Ed.; Maloch, Beth, Ed.; Hoffman, James V., Ed.; Schallert, Diane L., Ed.

2003-01-01

The National Reading Conference (NRC) Yearbook represents an archive of conference reports that have undergone the rigorous review that research demands, as well as an indicator of topics, ideas and concerns that occupied participants during the annual conference. With this 52nd volume of the Yearbook, the editors hope the reader finds a broad…

The end of an era? Midwifery conferences.

PubMed

Vilain, Annette Dalsgaard; Stewart, Sarah

2012-12-01

It has long been accepted that conferences are a useful mode of continuous professional development (CPD) (Russell 2010). Midwives welcome the chance to learn about recent practice developments, and the opportunity to network with each other in a face to face environment. However, barriers such as geographical isolation, time and financial constraints restrict midwives' ability to attend conferences (McIntosh 2007; Patterson and Davis 2007). At the same time, the effectiveness of conferences for CPD has been questioned (Guskey 2000). In these days of financial retrenchment, CPD has to be innovative and creative, offering ongoing support and learning in communities of practice that meet individual learning needs. The Virtual International Day of the Midwife (VIDM) is one such innovation. It is an annual 24 hour international synchronous online conference that celebrates the International Day of the Midwife on 5th May, and is freely open to all. Using the VIDM as a case study, this article discusses how online conferences may support and provide CPD for midwives.

2005 9th Annual Army Small Business Conference

DTIC Science & Technology

2005-11-03

field commanders who conduct acquisitions. All the Army’s major commands located in the United States will be represented. The conference...Engineer Squad Vehicle i r i l Mobile Gun System il yst Medical Evacuation Vehicle i l v ti i l Reconnaissance Vehicle iss i l Mortar Carrier rt r rri r...Manned Systems Unmanned Air Vehicles Class I ARV-A (L) Small (Manpackable) UGV Non-Line of Sight Cannon Non-Line of Sight Mortar Medical Treatment and

Modification of the photodynamic action of delta-aminolaevulinic acid (ALA) on rat pancreatoma cells by mitochondrial benzodiazepine receptor ligands.

PubMed Central

Ratcliffe, S. L.; Matthews, E. K.

1995-01-01

We have shown that addition of exogenous delta-aminolaevulinic acid (ALA) to rat pancreatoma AR4-2J cells in culture leads to the increased production of porphobilinogen (PBG) and the accumulation of photoactive protoporphyrin IX (PPix) in these cells. Exposure to light (lambda > 400 nm) at an intensity of 0.2 mW cm-2 for 8 min resulted in an ALA dose-dependent cytolysis of the cells, with an EC50 of 6.6 +/- 0.7 microM. This cytolytic effect was light intensity dependent, with greater cell destruction after exposure to light at an intensity of 0.47 mW cm-2 than at 0.2 mW cm-2; it was also dependent on the duration of illumination, cell survival decreasing with increasing illumination times. The photodestruction of the AR4-2J cells following exposure to ALA can be attributed to the production of endogenous PPix, a photoactive porphyrin that we have shown to generate singlet oxygen upon illumination, whereas ALA itself does not. Further investigation of the molecular mechanisms underlying the photodynamic action of ALA demonstrated the involvement of the mitochondrial (peripheral) benzodiazepine receptor (MBR), a high-affinity recognition site for dicarboxylic porphyrins, and especially PPix. The centrally acting benzodiazepine compounds clonazepam and flumazenil, which have negligible affinities for the MBR, had no effect on ALA-mediated phototoxicity. In contrast, both the isoquinoline carboxamide PK11195 and the benzodiazepine Ro 5-4864 ligands, displaying a high affinity for the MBR, did affect ALA-mediated phototoxicity, each markedly increasing the EC50 for cell photodestruction and thus exerting a photoprotective effect. It is concluded that the MBR may play an important role in the expression of ALA-mediated PPix phototoxicity and that MBR ligands, by diminishing the actions of endogenous PPix, have the potential to rescue cells from porphyrin-induced photolysis. PMID:7841044

2009 TOXICOLOGY AND RISK ASSESSMENT CONFERENCE

EPA Science Inventory

EPA has announced

The 2009 Toxicology and Risk Assessment Conference
Cincinnati Marriott North, West Chester (Cincinnati), OH
April 27-30, 2009 - Click to register!

The Annual Toxicology and Risk Ass...

2008 TOXICOLOGY AND RISK ASSESSMENT CONFERENCE

EPA Science Inventory

EPA has announced

The 2008 Toxicology and Risk Assessment Conference
Cincinnati Marriott North, West Chester (Cincinnati), OH
April 14 - 17, 2008 - Click to register!

The Annual Toxicology and Risk ...

2007 TOXICOLOGY AND RISK ASSESSMENT CONFERENCE

EPA Science Inventory

EPA has announced

The 2007 Toxicology and Risk Assessment Conference
Cincinnati Marriott North, West Chester (Cincinnati), OH
April 23- 26, 2007 - Click to register!

The Annual Toxicology and Risk Ass...

5-ALA based photodynamic management of glioblastoma

NASA Astrophysics Data System (ADS)

Rühm, Adrian; Stepp, Herbert; Beyer, Wolfgang; Hennig, Georg; Pongratz, Thomas; Sroka, Ronald; Schnell, Oliver; Tonn, Jörg-Christian; Kreth, Friedrich-Wilhelm

2014-03-01

Objective: Improvement of the clinical outcome of glioblastoma (GBM) patients by employment of fluorescence and photosensitization on the basis of 5-aminolevulinic acid (5-ALA) induced protoporphyrin IX (PpIX). Methods: In this report the focus is laid on the use of tumor selective PpIX fluorescence for stereotactic biopsy sampling and intra-operative treatment monitoring. In addition, our current concept for treatment planning is presented. For stereotactic interstitial photodynamic therapy (iPDT), radial diffusers were implanted into the contrast enhancing tumor volume. Spectroscopic measurements of laser light transmission and fluorescence between adjacent fibers were performed prior, during and post PDT. Results: PpIX concentrations in primary glioblastoma tissue show high intra- and inter-patient variability, but are usually sufficient for an effective PDT. During individual treatment attempts with 5-ALA based GBM-iPDT, transmission and fluorescence measurements between radial diffusers gave the following results: 1. In some cases, transmission after PDT is considerably reduced compared to the value before PDT, which may be attributable to a depletion of oxygenated hemoglobin and/or diffuse bleeding. 2. PpIX fluorescence is efficiently photobleached during PDT in all cases. Conclusion: iPDT with assessment of PpIX fluorescence and photobleaching is a promising treatment option. Individualization of treatment parameters appears to bear a potential to further improve clinical outcomes.

The 1993 Goddard Conference on Space Applications of Artificial Intelligence

NASA Technical Reports Server (NTRS)

Hostetter, Carl F. (Editor)

1993-01-01

This publication comprises the papers presented at the 1993 Goddard Conference on Space Applications of Artificial Intelligence held at the NASA/Goddard Space Flight Center, Greenbelt, MD on May 10-13, 1993. The purpose of this annual conference is to provide a forum in which current research and development directed at space applications of artificial intelligence can be presented and discussed.

Proceedings of Conference on the Personnel Director in the Desegregation Process.

ERIC Educational Resources Information Center

Moody, Charles D., Ed.; And Others

The Program for Educational Opportunity, an institute based at the University of Michigan and established by the Office of Education pursuant to Title IV of the 1964 Civil Rights Act, is designed to assist school districts in the process of desegregation. The Program annually conducts a series of conferences. The Conference on The Personnel…

Proceedings of the 9th Annual Conference on Manual Control

NASA Technical Reports Server (NTRS)

1973-01-01

Papers are reported which were presented at the conference in the areas of displays, ride qualities and handling, driving and psychomotor skills, control, system identification and signal detection, electrophysiological and systems analysis, and modelling.

Proceedings of the Second All-USGS Modeling Conference, February 11-14, 2008: Painting the Big Picture

USGS Publications Warehouse

Brady, Shailaja R.

2009-01-01

The Second USGS Modeling Conference was held February 11-14, 2008, in Orange Beach, Ala. Participants at the conference came from all U.S. Geological Survey (USGS) regions and represented all four science discipline - Biology, Geography, Geology, and Water. Representatives from other Department of the Interior (DOI) agencies and partners from the academic community also participated. The conference, which was focused on 'painting the big picture', emphasized the following themes: Integrated Landscape Monitoring, Global Climate Change, Ecosystem Modeling, and Hazards and Risks. The conference centered on providing a forum for modelers to meet, exchange information on current approaches, identify specific opportunities to share existing models and develop more linked and integrated models to address complex science questions, and increase collaboration across disciplines and with other organizations. Abstracts for the 31 oral presentations and more than 60 posters presented at the conference are included here. The conference also featured a field trip to review scientific modeling issues along the Gulf of Mexico. The field trip included visits to Mississippi Sandhill Crane National Wildlife Refuge, Grand Bay National Estuarine Research Reserve, the 5 Rivers Delta Resource Center, and Bon Secour National Wildlife Refuge. On behalf of all the participants of the Second All-USGS Modeling Conference, the conference organizing committee expresses our sincere appreciation for the support of field trip oganizers and leaders, including the managers from the various Reserves and Refuges. The organizing committee for the conference included Jenifer Bracewell, Sally Brady, Jacoby Carter, Thomas Casadevall, Linda Gundersen, Tom Gunther, Heather Henkel, Lauren Hay, Pat Jellison, K. Bruce Jones, Kenneth Odom, and Mark Wildhaber.

Twitter use at a family medicine conference: analyzing #STFM13.

PubMed

Mishori, Ranit; Levy, Brendan; Donvan, Benjamin

2014-09-01

The use of social media is expanding in medicine. A few articles sought to describe participant behavior using Twitter at scientific conferences. Family physicians are known as active participants in social media, but their behavior and practices at conferences have not been methodically described. We recorded all public tweets at the 2013 Society of Teachers of Family Medicine (STFM) Annual Spring Conference bearing the hashtag #STFM13, using commercially available services. We created a transcript of all tweets for the 5 days of the conference and 3 days before and after. We looked at the total number of tweets, number of original tweets and re-tweets, active users, most prolific users, and impressions. We categorized the content based on (1) Session related, (2) Social, (3) Logistics, (4) Ads, and (5) Other. We compared major metrics (but not content) to the 2012 STFM Annual Spring Conference. There were a total of 1,818 tweets from 181 user accounts: 13% of the conference registrants. The top tweeter accounted for over 15% of the total tweets, and the top 10 accounted for over 50% of the total volume. Most original tweets (69.7%) were related to session content. Social content came in second (14.2%), followed by other, logistics, and advertisement (7.6%, 6.9%, 1.6%). This preliminary analysis provides an initial snapshot of twitter activity at a family medicine conference. It may suggest avenues for further inquiry: trend identification, "influencer" identification, and qualitative analysis. Interdisciplinary research should focus on evaluation methods that can assess the quality, value, and impact of tweeting.

IFLA General Conference, 1986. Libraries Serving the General Public Division. Papers.

ERIC Educational Resources Information Center

International Federation of Library Associations and Institutions, The Hague (Netherlands).

This document includes papers on libraries serving the general public which were presented at the 1986 International Federation of Library Associations (IFLA) conference. The first paper, "Annual Reports of Sections and Round Tables of the Division of Libraries Serving the General Public" includes the following annual reports for fiscal year…

Research and Education: Top Priorities for Mentally Ill Children. Proceedings of the Second Annual Meeting and Conference of the National Society for Autistic Children (San Francisco, California, June 24-27, 1970).

ERIC Educational Resources Information Center

Park, Clara Claiborne, Ed.

The proceedings of the Second Annual Meeting and Conference of the National Society for Autistic Children begin with three brief statements regarding the Joint Commission on Mental Health of Children. Following are the keynote address by Edwin W. Martin concerning the rhetoric and reality of the Federal response to the educational needs of…

Second Annual David Derse Memorial Lecture and Award | Poster

Cancer.gov

By Anne Arthur, Guest Writer The Second Annual David Derse Memorial Lecture and Award presentation was held on November 12, 2013, at the NCI at Frederick Conference Center to honor David Derse’s outstanding research accomplishments and to stimulate the exchange of innovative ideas that Derse was well known for promoting throughout his scientific career. The Annual David Derse

The Annual African American Conference on Diabetes: evolving program evaluation with evolving program implementation.

PubMed

Houston, Jacquelyn M; Martin, Maurice; Williams, Joel E; Hill, Rhonda L

2006-01-01

According to 2003 Behavioral Risk Factor Surveillance System data, South Carolina has the fourth highest rate of overall diabetes among the 50 states (9.3%) but the second highest rate among African Americans (15.5%). Nationwide, African Americans are disproportionately affected by diabetes. In addition, 40% of the African American population in South Carolina lives in a rural area, and approximately 26% live at or below the poverty level. Lack of access to health care and diabetes education are additional barriers for people with diabetes and their families. Since 1997, the South Carolina Diabetes Prevention and Control Program and the Diabetes Today Advisory Council have sponsored the African American Conference on Diabetes, which targets African Americans with diabetes, their families, and their caregivers. This article describes the evolution of the conference and its evaluation. In 2002, we conducted focus groups with 20 African American conference attendees with diabetes to 1) assess the program's effects, 2) determine how to reach more individuals, and 3) improve programming. In 2004, we incorporated the preconference and postconference Diabetes Understanding Scale survey to assess the cognitive impact of the conference on participants. Focus group results revealed that participants wanted to attend the conference because of the opportunity to increase their knowledge and change their behaviors through 1) education, 2) social support, 3) resources, and 4) logistics. Self-rated understanding increased significantly after the conference for each cognitive understanding item on the Diabetes Understanding Scale. Focus group results suggested that participants who continue to attend the conference year after year may improve diabetes self-management skills. A quantitative evaluation showed that this 1-day diabetes education conference significantly increased short-term, self-rated cognitive understanding of diabetes behaviors.

The Second Annual International Space University Alumni Conference

NASA Technical Reports Server (NTRS)

Johnson, Les (Compiler); Robinson, Paul A. (Compiler)

1994-01-01

The papers presented at the conference reflect the multidisciplinary nature of the International Space University (ISU) and its alumni. The first papers presented hold special relevance to the design projects, and cover such topics as lunar-based astronomical instrumentation, solar lunar power generation, habitation on the moon, and the legal issues governing multinational astronauts conducting research in space. The next set of papers cover various technical issues such as project success assessment, satellite networks and space station dynamics, thus reflecting the diverse backgrounds of the ISU alumni.

Leading by Example? ALA Division Publications, Open Access, and Sustainability

ERIC Educational Resources Information Center

Hall, Nathan; Arnold-Garza, Sara; Gong, Regina; Shorish, Yasmeen

2016-01-01

This investigation explores scholarly communication business models in American Library Association (ALA) division peer-reviewed academic journals. Previous studies reveal the numerous issues organizations and publishers face in the academic publishing environment. Through an analysis of documented procedures, policies, and finances of five ALA…

Quality, Social Justice and Accountability in Education Worldwide. BCES Conference Books, Volume 13. Number 1

ERIC Educational Resources Information Center

Popov, Nikolay, Ed.; Wolhuter, Charl, Ed.; Ermenc, Klara Skubic, Ed.; Hilton, Gillian, Ed.; Ogunleye, James, Ed.; Niemczyk, Ewelina, Ed.

2015-01-01

The Annual International Conference of the Bulgarian Comparative Education Society is now running in its thirteenth year. From its modest beginnings thirteen years ago, to its impressive size today, a tradition has been the production of a conference book, consistently launched on the first day of the conference each year. This year, Volume 13 of…

Education in One World: Perspectives from Different Nations. BCES Conference Books, Volume 11

ERIC Educational Resources Information Center

Popov, Nikolay, Ed.; Wolhuter, Charl, Ed.; Almeida, Patrícia Albergaria, Ed.; Hilton, Gillian, Ed.; Ogunleye, James, Ed.; Chigisheva, Oksana, Ed.

2013-01-01

This volume contains papers submitted to the 11th Annual International Conference of the Bulgarian Comparative Education Society (BCES), held in Plovdiv, Bulgaria, 14-17 May 2013, and papers submitted to the 1st International Distance Partner Conference, organized by the International Research Centre "Scientific Cooperation,"…

Assessment Practices in Foreign Language Education: Dimension 2004. Selected Proceedings of the 2004 Joint Conference of the Southern Conference on Language Teaching and the Alabama Association of Foreign Language Teachers

ERIC Educational Resources Information Center

Cherry, C. Maurice, Ed.; Bradley, Lee, Ed.

2004-01-01

"Dimension" is the annual volume containing the selected, refereed, edited proceedings of each year's conference. On the eve of its 40th anniversary, the Southern Conference on Language Teaching (SCOLT) plans a special series of articles on assessment within the foreign language profession. The 2004 edition of "Dimension"…

First Annual Fuel Cell End Users Forum

DTIC Science & Technology

2011-05-03

UNCLASSIFIED: Dist A. Approved for public release 1 Conference Report First Annual Fuel Cell End Users Forum ...Report First Annual Fuel Cell End Users Forum 5a. CONTRACT NUMBER w56hzv-09-D-0154 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...End Users Forum was established to provide a user focused venue that enables a peer-to-peer support network to exchange information and gain knowledge

LJ Q&A "ALA Candidates": Library Advocacy x 2

ERIC Educational Resources Information Center

Berry, John N., III

2008-01-01

Library advocacy in one of two directions is the top priority of both Camila Alire and J. Linda Williams, the candidates campaigning to capture the 2009-10 term as president of the American Library Association (ALA). Alire, dean emeritus of the libraries of both the University of New Mexico and Colorado State University, will push for enhancements…

Research-Teaching Linkages: Practice and Policy. Proceedings of the Third Annual Conference of the National Academy for the Integration of Research, Teaching and Learning (3rd, Dublin, Ireland, November 11-12, 2009)

ERIC Educational Resources Information Center

Murphy, Jennifer, Ed.; Griffin, Carrie, Ed.; Higgs, Bettie, Ed.

2010-01-01

The third annual conference of the National Academy for Integration of Research, Teaching and Learning (NAIRTL) was held at Trinity College Dublin on 11-12 November 2009, and was attended by over 300 delegates. The theme--"Research-Teaching Linkages: Practice and Policy"--was timely and generated some fascinating papers, workshops and…

Sperm quality after swim up and density gradient centrifugation sperm preparation with supplementation of alpha lipoic acid (ALA): A preliminary study

NASA Astrophysics Data System (ADS)

Lestari, Silvia W.; Lestari, Sarah H.; Pujianto, Dwi A.

2018-02-01

Intra uterine insemination (IUI) as one of the treatment for infertility, persists low success rate. A factor that contributes to the unsuccessful of IUI is sperm preparation, performed through Swim-up (SU) and Density Gradient Centrifugation (DGC) methods. Furthermore, studies have shown that Alpha Lipoic Acid (ALA) is a potent antioxidant that could enhance the sperm motility and protect the DNA integrity of the sperm [1]. This study is aimed to re-evaluate the efficiency of the DGC and SU methods in selecting sperm before being transferred for IUI by the supplementation of ALA based on the sperm DNA integrity. Semen samples were obtained from 13 men from partners of women who are infertile (normozoospermia) and underwent IUI. Semen analysis based on the guideline of World Health Organization (WHO) 2010 was performed to measure the sperm motility and velocity, before and after sperm preparation. Then, samples were incubated with Alpha Lipoic Acid (ALA) in 0.625 mg (ALA 1), 1.25 mg (ALA 2) and 2.5 mg (ALA 3). The Sperm Chromatin Dispersion (SCD) test was performed to evaluate the sperm DNA Fragmentation Index (DFI). The percentage of motile sperm was higher in prepared sperm (post-DGC and post-SU) than in whole semen. Furthermore, the percentage of motile sperm was higher in post-DGC compared to post-SU. The level of DFI after the supplementation of ALA was decreased in prepared sperm compared to the whole semen. ALA was proved capable to select the better sperm quality with decreased sperm DNA fragmentation of prepared sperm in the all of DFI category.

Building on Family Strengths: Research and Services in Support of Children and Their Families. Proceedings of the Building on Family Strengths Annual Conference (12th, Portland, Oregon, June 23-25, 2005)

ERIC Educational Resources Information Center

Gordon, Lyn, Ed.; Bradley, Jennifer, Ed.; Aue, Nicole, Ed.; Holman, Ariel, Ed.

2006-01-01

The 12th Annual Building on Family Strengths Conference was held from June 23rd through June 25th 2005 in Portland, Oregon. Highlights included: (1) An information-packed keynote address by Dr. Richard M. Lerner on promoting positive youth development through enhancing the assets of communities; (2) An exciting research plenary panel session that…

The 2017 Bioinformatics Open Source Conference (BOSC)

PubMed Central

Harris, Nomi L.; Cock, Peter J.A.; Chapman, Brad; Fields, Christopher J.; Hokamp, Karsten; Lapp, Hilmar; Munoz-Torres, Monica; Tzovaras, Bastian Greshake; Wiencko, Heather

2017-01-01

The Bioinformatics Open Source Conference (BOSC) is a meeting organized by the Open Bioinformatics Foundation (OBF), a non-profit group dedicated to promoting the practice and philosophy of Open Source software development and Open Science within the biological research community. The 18th annual BOSC ( http://www.open-bio.org/wiki/BOSC_2017) took place in Prague, Czech Republic in July 2017. The conference brought together nearly 250 bioinformatics researchers, developers and users of open source software to interact and share ideas about standards, bioinformatics software development, open and reproducible science, and this year’s theme, open data. As in previous years, the conference was preceded by a two-day collaborative coding event open to the bioinformatics community, called the OBF Codefest. PMID:29118973

The 2017 Bioinformatics Open Source Conference (BOSC).

PubMed

Harris, Nomi L; Cock, Peter J A; Chapman, Brad; Fields, Christopher J; Hokamp, Karsten; Lapp, Hilmar; Munoz-Torres, Monica; Tzovaras, Bastian Greshake; Wiencko, Heather

2017-01-01

The Bioinformatics Open Source Conference (BOSC) is a meeting organized by the Open Bioinformatics Foundation (OBF), a non-profit group dedicated to promoting the practice and philosophy of Open Source software development and Open Science within the biological research community. The 18th annual BOSC ( http://www.open-bio.org/wiki/BOSC_2017) took place in Prague, Czech Republic in July 2017. The conference brought together nearly 250 bioinformatics researchers, developers and users of open source software to interact and share ideas about standards, bioinformatics software development, open and reproducible science, and this year's theme, open data. As in previous years, the conference was preceded by a two-day collaborative coding event open to the bioinformatics community, called the OBF Codefest.

Challenges for community-based forest management in the KoloAla site Manompana.

PubMed

Urech, Zora Lea; Sorg, Jean-Pierre; Felber, Hans Rudolph

2013-03-01

Following the IUCN 5th World Congress on Protected Areas in 2003, the then-President of Madagascar decided to increase the area of Madagascar's protected areas from 1.7 to 6 million ha. To combine the aims of protection and timber production, a new concept was developed through the establishment of community-based forest management (CBFM) sites, called KoloAla. However, experience shows that similar management transfers to communities in Madagascar have only been successful in a very few cases. We aimed to explore the success to be expected of this new approach in the particular case of the Manompana corridor at Madagascar's eastern coast. In a first step, the readiness of the corridor's resource users for CBFM has been analysed according to the seven resource users' attributes developed by Ostrom that predict an effective self-organized resource management. In a second step, we explored how KoloAla addresses known challenges of Madagascar's CBFM. Analyses lead in a rather sober conclusion. Although KoloAla attempts to address the goals of poverty alleviation, biodiversity conservation and timber production under a single umbrella, it does so in a rather non-innovative way. Challenges with regard to the state's environmental governance, agricultural inefficiency and thus deforestation remain unsolved.

Challenges for Community-Based Forest Management in the KoloAla Site Manompana

NASA Astrophysics Data System (ADS)

Urech, Zora Lea; Sorg, Jean-Pierre; Felber, Hans Rudolph

2013-03-01

Following the IUCN 5th World Congress on Protected Areas in 2003, the then-President of Madagascar decided to increase the area of Madagascar's protected areas from 1.7 to 6 million ha. To combine the aims of protection and timber production, a new concept was developed through the establishment of community-based forest management (CBFM) sites, called KoloAla. However, experience shows that similar management transfers to communities in Madagascar have only been successful in a very few cases. We aimed to explore the success to be expected of this new approach in the particular case of the Manompana corridor at Madagascar's eastern coast. In a first step, the readiness of the corridor's resource users for CBFM has been analysed according to the seven resource users' attributes developed by Ostrom that predict an effective self-organized resource management. In a second step, we explored how KoloAla addresses known challenges of Madagascar's CBFM. Analyses lead in a rather sober conclusion. Although KoloAla attempts to address the goals of poverty alleviation, biodiversity conservation and timber production under a single umbrella, it does so in a rather non-innovative way. Challenges with regard to the state's environmental governance, agricultural inefficiency and thus deforestation remain unsolved.

Evaluation of Partial Cut-out of Sacroiliac Screws From the Sacral Ala Slope via Pelvic Inlet and Outlet View.

PubMed

Zhang, Jingwei; Hamilton, Ryan; Li, Ming; Ebraheim, Nabil A; He, Xianfeng; Liu, Jiayong; Zhu, Limei

2015-12-01

An anatomic and radiographic study of placement of sacroiliac screws. The aim of this study was to quantitatively assess the risk of partial cut-out of sacroiliac screws from the sacral ala slope via inlet and outlet view. The partial cut-out of sacroiliac screws from the superior surface of sacral ala can jeopardize the L5 nerve root, which is difficult to identify on the pelvic inlet and outlet views. Computed tomography images of 60 patients without pelvic ring deformity or injury were used to measure the width (on inlet view) and height (on outlet view) of the sacral ala. The angle of the sacral ala slope was measured on lateral view. According to the measured parameters, the theoretical safe trajectories of screw placement were calculated using inverse trigonometric functions. Under fluoroscopic guidance, a sacroiliac screw was placed close to the midline on both inlet and outlet views, including posterosuperior, posteroinferior, anterosuperior, and anteroinferior regions to the midline. The incidence of screw partial cut-out from the superior surface of sacral ala was identified. The measured widths and heights of the sacral alas were 28.1 ± 2.8 and 29.8 ± 3.1 mm, respectively. The average angle between the superior aspect of the S1 vertebral body and the superior aspect of the sacral ala was 37.2 ± 2.5 degrees. The rate of partial cut-out of the screws from the superior surface of sacral ala slope was 12.5% (5/40) in posterosuperior, 0% (0/40) in posteroinferior, 70% (28/40) in anterosuperior, and 20% (8/40) in anteroinferior. To avoid the risk of partial cut-out from sacroiliac screw placement, more precise description should be added to the conventional description: the sacroiliac screws should be placed at the inferior half portion on outlet view and at the posterior half portion on inlet view. 4.

Conference in Rhetorical Criticism: Address of the Conference and Commended Papers (2nd, Hayward, Calif., May 1967).

ERIC Educational Resources Information Center

Barrett, Harold, Ed.; And Others

At the second annual Cal-State Hayward Conference in Rhetorical Criticism, upper division and graduate students from 17 colleges and universities presented papers on the theory, history, and criticism of rhetoric. Panels of faculty members from the same colleges and universities, serving as editor-critics, judged the six papers in this volume as…

The net effect: spanning diseases, crossing borders—highlights from the fourth triennial APCA conference and annual HPCA conference for palliative care

PubMed Central

Downing, J; Namisango, E; Kiyange, F; Luyirika, E; Gwyther, L; Enarson, S; Kampi, J; Sithole, Z; Kemigisha-Ssali, E; Masclee, M; Mukasa, I

2013-01-01

The African Palliative Care Association (APCA) jointly hosted its triennial palliative care conference for Africa with the Hospice and Palliative Care Association of South Africa (HPCA) on 17–20 September 2013 in Johannesburg, South Africa. At the heart of the conference stood a common commitment to see patient care improved across the continent. The theme for the conference, ‘The Net Effect: Spanning Diseases, Crossing Borders’, reflected this joint vision and the drive to remember the ‘net effect’ of our work in palliative care—that is, the ultimate impact of the care that we provide for our patients and their families across the disease and age spectrum and across the borders of African countries. The conference, held in Johannesburg, brought together 471 delegates from 34 countries. The key themes and messages from the conference are encapsulated in ten ‘C’s of commitment to political will and support at the highest levels of governance; engaging national, regional, and international bodies; collaboration; diversity; palliative care for children; planning for human resources and capacity building; palliative care integration at all levels; developing an evidence base for palliative care in Africa; using new technologies; and improved quality of care. Participants found the conference to be a forum that challenged their understanding of the topics presented, as well as enlightening in terms of applying best practice in their own context. Delegates found a renewed commitment and passion for palliative care and related health interventions for children and adults with life-limiting and life-threatening illnesses within the region. This conference highlighted many of the developments in palliative care in the region and served as a unique opportunity to bring people together and serve as a lynchpin for palliative care provision and development in Africa. The delegates were united in the fact that together we can ‘span diseases,’ ‘cross borders

NECC 2002: National Educational Computing Conference Proceedings (23rd, San Antonio, Texas, June 17-19, 2002).

ERIC Educational Resources Information Center

National Educational Computing Conference.

The National Educational Computing Conference (NECC) is the largest conference of its kind in the world. This document is the Proceedings from the 23rd annual National Educational Computing Conference (NECC) held in San Antonio, June 17-19, 2002. Included are: general information; schedule of events; evaluation form; and the program. Information…

SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking.

PubMed

Bowton, E; Saunders, C; Reddy, I A; Campbell, N G; Hamilton, P J; Henry, L K; Coon, H; Sakrikar, D; Veenstra-VanderWeele, J M; Blakely, R D; Sutcliffe, J; Matthies, H J G; Erreger, K; Galli, A

2014-10-14

Emerging evidence associates dysfunction in the dopamine (DA) transporter (DAT) with the pathophysiology of autism spectrum disorder (ASD). The human DAT (hDAT; SLC6A3) rare variant with an Ala to Val substitution at amino acid 559 (hDAT A559V) was previously reported in individuals with bipolar disorder or attention-deficit hyperactivity disorder (ADHD). We have demonstrated that this variant is hyper-phosphorylated at the amino (N)-terminal serine (Ser) residues and promotes an anomalous DA efflux phenotype. Here, we report the novel identification of hDAT A559V in two unrelated ASD subjects and provide the first mechanistic description of its impaired trafficking phenotype. DAT surface expression is dynamically regulated by DAT substrates including the psychostimulant amphetamine (AMPH), which causes hDAT trafficking away from the plasma membrane. The integrity of DAT trafficking directly impacts DA transport capacity and therefore dopaminergic neurotransmission. Here, we show that hDAT A559V is resistant to AMPH-induced cell surface redistribution. This unique trafficking phenotype is conferred by altered protein kinase C β (PKCβ) activity. Cells expressing hDAT A559V exhibit constitutively elevated PKCβ activity, inhibition of which restores the AMPH-induced hDAT A559V membrane redistribution. Mechanistically, we link the inability of hDAT A559V to traffic in response to AMPH to the phosphorylation of the five most distal DAT N-terminal Ser. Mutation of these N-terminal Ser to Ala restores AMPH-induced trafficking. Furthermore, hDAT A559V has a diminished ability to transport AMPH, and therefore lacks AMPH-induced DA efflux. Pharmacological inhibition of PKCβ or Ser to Ala substitution in the hDAT A559V background restores AMPH-induced DA efflux while promoting intracellular AMPH accumulation. Although hDAT A559V is a rare variant, it has been found in multiple probands with neuropsychiatric disorders associated with imbalances in DA neurotransmission

Strategic Choice: Making Better Decisions through Better Understanding of Institutions and Their Environments. Proceedings of the Annual Conference of the North East Association for Institutional Research (15th, Providence, Rhode Island, October 23-25, 1988).

ERIC Educational Resources Information Center

North East Association for Institutional Research.

The 1988 annual conference of the North East Association for Institutional Research focused on strategic choice. Selected papers included: "Fact Books: Paper-Based or Electronic?" (T. Gusler); "Electronic Factbooks" (J. Jacobsen); "A Comparative Analysis of Community College Administrators' and Adult Evening Credit Course…

The sixth conference on satellite meteorology and oceanography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hauth, F.F.; Purdom, J.F.W.

The Sixth Conference on Satellite Meteorology and Oceanography was held in conjunction with the AMS Annual Meeting in Atlanta, Georgia, the week of 6 January 1992. Over 150 scientific papers were presented orally or in poster sessions. Joint sessions were held with the Symposium on Weather Forecasting and the Eighth International Conference on Interactive Information and Processing Systems for Meteorology, Oceanography, and Hydrology. The quality of the papers in the preprint volume, as well as in the presentations at both oral and poster sessions, reflects the robustness of national and international operational and research interests in satellite meteorology and oceanography.more » A preprint volume for this conference is available through the AMS.« less

Association between PPAR-γ2 Pro12Ala genotype and insulin resistance is modified by circulating lipids in Mexican children

PubMed Central

Stryjecki, Carolina; Peralta-Romero, Jesus; Alyass, Akram; Karam-Araujo, Roberto; Suarez, Fernando; Gomez-Zamudio, Jaime; Burguete-Garcia, Ana; Cruz, Miguel; Meyre, David

2016-01-01

The Pro12Ala (rs1801282) polymorphism in peroxisome proliferator-activated receptor-γ2 (PPAR-γ2) has been convincingly associated with insulin resistance (IR) and type 2 diabetes (T2D) among Europeans, in interaction with a high-fat diet. Mexico is disproportionally affected by obesity and T2D however, whether the Pro12Ala polymorphism is associated with early metabolic complications in this population is unknown. We assessed the association of PPAR-γ2 Pro12Ala with metabolic traits in 1457 Mexican children using linear regression models. Interactions between PPAR-γ2 Pro12Ala and circulating lipids on metabolic traits were determined by adding an interaction term to regression models. We observed a high prevalence of overweight/obesity (49.2%), dyslipidemia (34.9%) and IR (11.1%). We detected nominally significant/significant interactions between lipids (total cholesterol, HDL-cholesterol, LDL-cholesterol), the PPAR-γ2 Pro12Ala genotype and waist-to-hip ratio, fasting insulin, HOMA-IR and IR (9.30 × 10−4  ≤ Pinteraction ≤ 0.04). Post-hoc subgroup analyses evidenced that the association between the PPAR-γ2 Pro12Ala genotype and fasting insulin, HOMA-IR and IR was restricted to children with total cholesterol or LDL-cholesterol values higher than the median (0.02 ≤ P ≤ 0.03). Our data support an association of the Pro12Ala polymorphism with IR in Mexican children and suggest that this relationship is modified by dyslipidemia. PMID:27075119

Inferior oblique muscle origin: horizontal location in relation to ala nasi and its gender difference.

PubMed

Takahashi, Yasuhiro; Kakizaki, Hirohiko; Kohjima, Kiwamu; Nakano, Takashi; Asamoto, Ken; Ichinose, Akihiro; Iwaki, Masayoshi

2013-01-01

We studied the horizontal location of the inferior oblique muscle (IOM) origin in relation to the ipsilateral ala nasi and compared the results between genders in 76 orbits of 38 Japanese cadavers. Consequently, the IOM origin was located 1.2 mm laterally to the vertical line through the lateral margin of the ipsilateral ala nasi. No significant difference was noted between genders (males, 1.3 mm; females, 0.9 mm; P = 0.257, Student t test) or between sides (right, 1.1 mm; left, 1.3 mm; P = 0.570, Student t test). In contrast, the mean interalae-nasi distance was 39.8 mm and was significantly greater in males than that in females (males, 40.8 mm; females, 38.6 mm; P = 0.049, Student t test). The ala nasi can be used as a reference point irrespective of gender or side for identifying the IOM origin during oculoplastic surgery.

Impact of the PPAR-γ2 Pro12Ala Polymorphism and ACE Inhibitor Therapy on New-Onset Microalbuminuria in Type 2 Diabetes: Evidence From BENEDICT

PubMed Central

De Cosmo, Salvatore; Motterlini, Nicola; Prudente, Sabrina; Pellegrini, Fabio; Trevisan, Roberto; Bossi, Antonio; Remuzzi, Giuseppe; Trischitta, Vincenzo; Ruggenenti, Piero

2009-01-01

OBJECTIVE Cross-sectional studies found less microalbuminuria in type 2 diabetic patients with the Ala12 allele of the peroxisome proliferator–activated receptor-γ2 (PPAR-γ2) Pro12Ala polymorphism. We prospectively evaluated the association between Pro12Ala polymorphism (rs1801282) and new-onset microalbuminuria. RESEARCH DESIGN AND METHODS Pro12Ala polymorphism was genotyped by TaqMan-based assay in genomic DNA of 1,119 consenting patients from BErgamo NEphrologic DIabetic Complications Trial (BENEDICT)—a prospective, randomized trial evaluating ACE inhibition effect on new-onset microalbuminuria (albuminuria 20–200 μg/min in at least two of three consecutive overnight urine collections in two consecutive visits) in hypertensive type 2 diabetes with albuminuria <20 μg/min at inclusion. RESULTS Baseline characteristics of Ala (Ala/Ala or Ala/Pro) carriers and Pro/Pro homozygotes were similar, with a nonsignificant trend to lower albuminuria (P = 0.1107) in the 177 Ala carriers. Over a median (interquartile range) of 44.0 (17.1–51.9) months, 7 (4%) Ala carriers and 86 (9.1%) Pro/Pro homozygotes developed microalbuminuria (hazard ratio [HR] 0.45 [95% CI 0.21–0.97]; P = 0.042). Final albuminuria was significantly lower in Ala carriers than Pro/Pro homozygotes (7.3 ± 9.1 vs. 10.5 ± 24.9 μg/min, respectively), even after adjustment for baseline albuminuria (P = 0.048). Baseline and follow-up blood pressure and metabolic control were similar in both groups. Incidence of microalbuminuria was significantly decreased by ACE versus non-ACE inhibitor therapy in Pro/Pro homozygotes (6.3 vs. 11.9%, respectively, HR 0.46 [0.29–0.72]; P < 0.001). CONCLUSIONS In type 2 diabetes, the Ala allele protects from worsening albuminuria and new-onset microalbuminuria, and ACE inhibition blunts the excess risk of microalbuminuria associated with the Pro/Pro genotype. Evaluating Pro12Ala polymorphism may help identifying patients at risk who may benefit the most from

Effects of Ala-Gln feeding strategies on growth, metabolism, and crowding stress resistance of juvenile Cyprinus carpio var. Jian.

PubMed

Chen, Xiu-Mei; Guo, Gui-Liang; Sun, Li; Yang, Qiu-Shi; Wang, Gui-Qin; Qin, Gui-Xin; Zhang, Dong-Ming

2016-04-01

The present study was conducted to evaluate the effects of different L-alanyl-l-glutamine (Ala-Gln) feeding strategies on the growth performance, metabolism and crowding stress resistance related parameters in juvenile Jian carp (Cyprinus carpio var. Jian) under crowded condition (80 g/L). Juvenile Jian carp (initial weight 26.1 ± 0.6 g) were distributed into five groups which fed with graded concentrations (0% or 1.0%) of Ala-Gln for eight weeks. Control group (I, 0/0) fed with control diet (0% Ala-Gln) throughout the feeding trial. The other four groups employed different control and experimental diet feeding strategies ranging from two weeks control diet fed and two weeks experimental diet (1% Ala-Gln) fed (II, 0/2) to eight weeks experimental diet fed (V, 4/4). Results revealed that Mean weight gain (MEG) under all different feeding strategies of Ala-Gln were significantly higher than that of the control group (p < 0.05), and MEG of group II (201.90%) was even higher than that of group IV (184.70%). Liver glycogen and blood total protein of groups II, III and V were significantly higher than that in groups I and IV (p < 0.05). The highest level of serum thyroxine (10.07 ng/ml), insulin-like growth factor-I (52.40 ng/ml) and insulin (9.73 μ IU/mL) were observed in group V. However, diet supplemented with Ala-Gln did not affect the levels of serum glucose, cortisol and catecholamine in fish. The mRNA expression of GR1a, GR1b and GR2 were also significantly changed in Ala-Gln supplementation groups compared with control group (p < 0.05). After fish intraperitoneally injected with virulent Aeromonas hydrophila, the fish survival rates were significantly increased in all Ala-Gln supplementation groups compared with control group (p < 0.05). Results from the present experiment showed the importance of dietary supplementation of Ala-Gln in benefaction of the growth performance, metabolism and crowding stress resistance in Jian carp breeding. The

PIALA '95. Preservation of Culture through Archives and Libraries. Papers from the Annual Pacific Islands Association of Libraries and Archives Conference (5th, Colonia, Yap, Federated States of Micronesia, November 6-10, 1995).

ERIC Educational Resources Information Center

Cohen, Arlene, Ed.

The annual conference of the Pacific Islands Association of Libraries and Archives addressed various topics of interest to librarians, archivists, and educators in the Pacific Islands. The proceedings include welcoming remarks by 2 Yap state government officials and PIALA President Herbert Del Rosario; a keynote address by Dr. Marcia J.…

Transcending the Rhetoric of "Family Values": Celebrating Families of Choice and Families of Value. The 2008 Adult Education Research Conference (AERC) Lesbian, Gay, Bisexual, Transgender, Queer & Allies (LGBTQ&A) Pre-Conference

ERIC Educational Resources Information Center

Bettinger, Thomas V., Ed.

2008-01-01

This pre-conference, held in conjunction with the 49th annual Adult Education Research Conference at the University of Missouri-St. Louis in June, 2008, brought together graduate students and adult education researchers and practitioners from a variety of academic and workplace settings to discuss issues related to sexual minorities in…

Structural and functional analysis of the ASM p.Ala359Asp mutant that causes acid sphingomyelinase deficiency.

PubMed

Acuña, Mariana; Castro-Fernández, Víctor; Latorre, Mauricio; Castro, Juan; Schuchman, Edward H; Guixé, Victoria; González, Mauricio; Zanlungo, Silvana

2016-10-21

Niemann-Pick disease (NPD) type A and B are recessive hereditary disorders caused by deficiency in acid sphingomyelinase (ASM). The p.Ala359Asp mutation has been described in several patients but its functional and structural effects in the protein are unknown. In order to characterize this mutation, we modeled the three-dimensional ASM structure using the recent available crystal of the mammalian ASM as a template. We found that the p.Ala359Asp mutation is localized in the hydrophobic core and far from the sphingomyelin binding site. However, energy function calculations using statistical potentials indicate that the mutation causes a decrease in ASM stability. Therefore, we investigated the functional effect of the p.Ala359Asp mutation in ASM expression, secretion, localization and activity in human fibroblasts. We found a 3.8% residual ASM activity compared to the wild-type enzyme, without changes in the other parameters evaluated. These results support the hypothesis that the p.Ala359Asp mutation causes structural alterations in the hydrophobic environment where ASM is located, decreasing its enzymatic activity. A similar effect was observed in other previously described NPDB mutations located outside the active site of the enzyme. This work shows the first full size ASM mutant model describe at date, providing a complete analysis of the structural and functional effects of the p.Ala359Asp mutation over the stability and activity of the enzyme. Copyright © 2016 Elsevier Inc. All rights reserved.

PPARγ Pro12Ala interacts with fat intake for obesity and weight loss in a behavioural treatment based on the Mediterranean diet

PubMed Central

Garaulet, Marta; Smith, Caren E; Hernández-González, Teresa; Lee, Yu-Chi; Ordovás, Jose M.

2014-01-01

Scope The goal of this study was to examine whether the Pro12Ala polymorphism of peroxisome proliferator-activated receptor γ (PPARγ) is associated with insulin resistance, obesity and weight loss and to analyze potential interactions between fat intake and PPARγ polymorphism in a Spanish overweight/obese population. Materials and methods We recruited 1465 subjects enrolled in a behavioural treatment program for obesity based on a Mediterranean diet, which included the following: dietary treatment, physical activity, nutritional education and behavioral techniques. A significant association was found between PPARγ2 Pro12Ala genotype and plasma insulin concentration and homeostasis model assessment insulin resistance. Subjects with the Ala12 genotype had lower insulin levels than those with the Pro12Pro genotype. We detected a gene–diet interaction between the PPARγ Pro12Ala polymorphism and MUFA for BMI and body fat. Furthermore, we detected an interaction between the PPARγ Pro12Ala polymorphism and fat intake for total weight loss (p<0.001). When total fat intake was high, Ala12-carriers exhibited a significantly lower percentage of total weight loss than major-allele-carriers (p=0.037). Conclusion Data are consistent with previous results showing a protective role for the Ala12 allele against insulin resistance, and replicate an earlier study that detected an interaction between dietary MUFA and PPARγ2 for BMI. Our detection of a gene–diet interaction between PPARγ Pro12Ala and fat intake for weight loss may explain previous discrepancies among different studies. PMID:22102511

An organic solvent-stable lipase from a newly isolated Staphylococcus aureus ALA1 strain with potential for use as an industrial biocatalyst.

PubMed

Ben Bacha, Abir; Moubayed, Nadine Ms; Al-Assaf, Alaa

2016-05-01

In this study, a new strain, ALA1, was identified as Staphylococcus aureus by biochemical tests, and its 16S ribosomal DNA sequence was isolated from dromedary milk. ALA1 lipase production was optimized in shake flask experiments and measured with varying pH (3-11), temperature (20-55 °C) and substrate concentrations. The maximum lipase production was recorded at pH 8 and 30 °C for up to 30 H of culture period for the S. aureus ALA1 strain. Among the substrates tested, selected carbon sources, xylose, nitrogen source, yeast extract, and olive oil (1%) were suitable for maximizing lipase production. The effects of surfactants were investigated and showed that Tween 20, Tween 80, and Triton X-100 prevented lipase production. Interestingly, isolate ALA1 was able to grow in high concentrations of benzene or toluene (up to 50% (v/v)). Moreover, the lipolytic activity of the S. aureus ALA1 lipase was stimulated by diethyl ether, whereas almost 100% of S. aureus ALA1 lipase activity was retained in 25% acetone, acetonitrile, benzene, 2-propanol, ethanol, methanol, or toluene. Because of its stability in organic solvent, the S. aureus ALA1 lipase was used as a biocatalyst to synthesize high levels of added value molecules. S. aureus ALA1 lipase could be considered as an ideal choice for applications in detergent formulations because of its high stability and compatibility with various surfactants, oxidizing agents, and commercial detergents. © 2015 International Union of Biochemistry and Molecular Biology, Inc.

A novel tumor-activated ALA fusion protein for specific inhibition on the growth and invasion of breast cancer cells MDA-MB-231.

PubMed

Liu, Xiufeng; Liu, Xintong; Sunchen, Suwen; Liu, Meixia; Shen, Chen; Wu, Juanjuan; Zhao, Wanli; Yu, Boyang; Liu, Jihua

2017-11-01

The aim of this research was to develop a novel ALA fusion protein for target to the malignant cells surface with high uPAR expression and locally release of the scorpion toxin AGAP in an uPA-cleavable manner. It will provide an effective approach for controlled release of the peptide toxins to treat cancerous cells. The ALA fusion proteins were expressed in pichia pastoris, and the recombinant proteins were purified by Ni-NTA affinity chromatography. The proteins were added to human breast cancer cells (MDA-MB-231) and human embryonic kidney cells (HEK-293) in order to investigate the characteristic of selective targeting and releasing of scorpion toxin AGAP in cancer cells with high uPAR expression. The inhibitory effect of ALA on MDA-MB-231, MCF7, LO2 and HEK-293 was evaluated by MTT assay. Moreover, the antiproliferation mechanism of ALA was determined by flow cytometric and western blot analysis. The results showed that ALA could target MDA-MB-231 cells and the scorpion toxin AGAP could be released with high efficiency and selectivity. ALA inhibited the growth and invasion of breast cancer cells MDA-MB231. Also, cell apoptosis pathway was found to be associated with the inhibition mechanism of ALA according to the data of flow cytometric and western blot analysis. Therefore, ALA could be a novel antitumor candidate for targeting treatment of malignant cell. This study successfully demonstrated that fusion of biotoxins with tumor target domain could provide a simple yet effective way to delivery of peptide or protein drugs.

Infraorbital foramen: horizontal location in relation to ala nasi.

PubMed

Takahashi, Yasuhiro; Kakizaki, Hirohiko; Nakano, Takashi

2011-01-01

To examine the horizontal location of the infraorbital foramen in relation to the ala nasi. Fifty-six orbits of 28 Japanese cadavers (18 male and 10 female cadavers; average death age, 79.7 years), fixed in 10% buffered formalin, were used. The horizontal distance from the vertical line through the lateral margin of the ala nasi to the medial margin of the infraorbital foramen (the horizontal distance) and the transverse diameter of the infraorbital foramen (the transverse diameter) were examined. Values were compared between genders and sides using Student's t test. The mean horizontal distance was 4.9 mm, with no significant difference between genders (male, 5.2 mm; female, 4.4 mm; p = 0.150) or sides (right, 4.9 mm; left, 4.9 mm; p = 0.944). The mean transverse diameter was 5.5 mm. Although there was no significant difference in this diameter between sides (right, 5.3 mm; left, 5.6 mm; p = 0.358), there was a significant difference between genders (male, 5.7 mm; female, 5.1 mm; p = 0.033). The horizontal distance had no gender difference. This value is available irrespective of gender in surgery.

Manganese superoxide dismutase Ala-9Val polymorphism and risk of breast cancer in a population-based case–control study of African Americans and whites

PubMed Central

Millikan, Robert C; Player, Jon; de Cotret, Allan René; Moorman, Patricia; Pittman, Gary; Vannappagari, Vani; Tse, Chiu-Kit J; Keku, Temitope

2004-01-01

Introduction A polymorphism in the manganese superoxide dismutase (MnSOD) gene, Ala-9Val, has been examined in association with breast cancer risk in several epidemiologic studies. Results suggest that the Ala allele increases the risk of breast cancer and modifies the effects of environmental exposures that produce oxidative damage to DNA. Methods We examined the role of the MnSOD Ala-9Val polymorphism in a population-based case–control study of invasive and in situ breast cancer in North Carolina. Genotypes were evaluated for 2025 cases (760 African Americans and 1265 whites) and for 1812 controls (677 African Americans and 1135 whites). Results The odds ratio for MnSOD Ala/Ala versus any MnSOD Val genotypes was not elevated in African Americans (odds ratio = 0.9, 95% confidence interval = 0.7–1.2) or in whites (odds ratio = 1.0, 95% confidence interval = 0.8–1.2). Greater than additive joint effects were observed for the Ala/Ala genotype and smoking, radiation to the chest, and occupational exposure to ionizing radiation. Antagonism was observed between the Ala/Ala genotype and the use of nonsteroidal anti-inflammatory drugs. Conclusions The MnSOD genotype may contribute to an increased risk of breast cancer in the presence of specific environmental exposures. These results provide further evidence for the importance of reactive oxygen species and of oxidative DNA damage in the etiology of breast cancer. PMID:15217492

2017 Brick & Click: An Academic Conference (17th, Maryville, Missouri, November 3, 2017)

ERIC Educational Resources Information Center

Baudino, Frank, Ed.; Hart, Kathy, Ed.; Johnson, Carolyn, Ed.

2017-01-01

Eighteen scholarly papers and fifteen abstracts comprise the content of the seventeenth annual Brick and Click Libraries Conference, held annually at Northwest Missouri State University in Maryville, Missouri. The proceedings, authored by academic librarians and presented at the symposium, portray the contemporary and future face of librarianship.…

CSUN's Conference Advances Opportunities for People with Disabilities

ERIC Educational Resources Information Center

Williams, John M.

2006-01-01

This article reports the highlights of the recently concluded Annual International Technology and Persons with Disabilities Conference organized by California State University at Northridge. Attendees from more than 30 countries learned about services provided by the Social Security Administration, GeorgiaTech (CATEA), NISH, Computer/Electronic…

The 1990 Goddard Conference on Space Applications of Artificial Intelligence

NASA Technical Reports Server (NTRS)

Rash, James L. (Editor)

1990-01-01

The papers presented at the 1990 Goddard Conference on Space Applications of Artificial Intelligence are given. The purpose of this annual conference is to provide a forum in which current research and development directed at space applications of artificial intelligence can be presented and discussed. The proceedings fall into the following areas: Planning and Scheduling, Fault Monitoring/Diagnosis, Image Processing and Machine Vision, Robotics/Intelligent Control, Development Methodologies, Information Management, and Knowledge Acquisition.

AAZPA Annual Conference Proceedings (Columbus, Ohio, September 8-12, 1985).

ERIC Educational Resources Information Center

American Association of Zoological Parks and Aquariums, Wheeling, WV.

Papers presented at the 1985 conference of the American Association of Zoological Parks and Aquariums (AAZPA) are provided in these proceedings. The papers are listed alphabetically by first author in the subject index (table of contents) under these headings: birds (seven papers); conservation and research (eight papers); education (14 papers);…

Transition to an IP Environment. A Report of the Annual Aspen Institute Conference on Telecommunications Policy (15th, Aspen, Colorado, August 12-16, 2000) with Thoughts on the Implications of Technological Change for Telecommunications Policy.

ERIC Educational Resources Information Center

Entman, Robert M.; Katz, Michael L.

The Aspen Institute's Communications and Society Program convened leaders and experts in the telecommunications and related fields to address telecommunications regulation in an IP (Internet Protocols) environment at the 15th annual Aspen Institute Telecommunications Policy Conference (Aspen, Colorado, August 12-16, 2000). The report from this…

55th Annual Canadian Society for Molecular Biosciences Conference on Epigenetics and Genomic Stability. Whistler, British Columbia, Canada, 14–18 March 2012.

PubMed

Nelson, Christopher J; Ausió, Juan

2012-06-01

The 55th Annual Canadian Society for Molecular Biosciences Conference on Epigenetics and Genomic Stability in Whistler, Canada, 14-18 March 2012, brought together 31 speakers from different nationalities. The organizing committee, led by Jim Davie (Chair) at the University of Manitoba (Manitoba, Canada), consisted of several established researchers in the fields of chromatin and epigenetics from across Canada. The meeting was centered on the contribution of epigenetics to gene expression, DNA damage and repair, and the role of environmental factors. A few interesting talks on replication added some insightful information on the controversial issue of histone post-translational modifications as genuine epigenetic marks that are inherited through cell division.

ALA-induced PpIX spectroscopy for brain tumor image-guided surgery

NASA Astrophysics Data System (ADS)

Valdes, Pablo A.; Leblond, Frederic; Kim, Anthony; Harris, Brent T.; Wilson, Brian C.; Paulsen, Keith D.; Roberts, David W.

2011-03-01

Maximizing the extent of brain tumor resection correlates with improved survival and quality of life outcomes in patients. Optimal surgical resection requires accurate discrimination between normal and abnormal, cancerous tissue. We present our recent experience using quantitative optical spectroscopy in 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) fluorescence-guided resection. Exogenous administration of ALA leads to preferential accumulation in tumor tissue of the fluorescent compound, PpIX, which can be used for in vivo surgical guidance. Using the state of the art approach with a fluorescence surgical microscope, we have been able to visualize a subset of brain tumors, but the sensitivity and accuracy of fluorescence detection for tumor tissue with this system are low. To take full advantage of the biological selectivity of PpIX accumulation in brain tumors, we used a quantitative optical spectroscopy system for in vivo measurements of PpIX tissue concentrations. We have shown that, using our quantitative approach for determination of biomarker concentrations, ALA-induced PpIX fluorescence-guidance can achieve accuracies of greater than 90% for most tumor histologies. Here we show multivariate analysis of fluorescence and diffuse reflectance signals in brain tumors with comparable diagnostic performance to our previously reported quantitative approach. These results are promising, since they show that technological improvements in current fluorescence-guided surgical technologies and more biologically relevant approaches are required to take full advantage of fluorescent biomarkers, achieve better tumor identification, increase extent of resection, and subsequently, lead to improve survival and quality of life in patients.

36th Annual David W. Smith Workshop on Malformations and Morphogenesis: Abstracts of the 2015 annual meeting.

PubMed

Gripp, Karen W; Adam, Margaret P; Hudgins, Louanne; Carey, John C

2016-07-01

The 36th Annual David W Smith Workshop on Malformations and Morphogenesis was held on August 14-19, 2015 at the Harbourtowne Conference Center in St. Michaels Maryland. The Workshop, which honors the legacy of David W Smith, brought together over 120 clinicians and researchers interested in congenital malformations and their underlying mechanisms of morphogenesis. As is the tradition of the meeting, the Workshop highlighted five themes besides mechanisms of morphogenesis: Rasopathies, Eye Malformations, Therapeutics, Prenatal Diagnosis, and Disorders of Sex Development. This Conference Report includes the abstracts presented at the 2015 Workshop. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

ALA-based fluorescent diagnosis of malignant oral lesions in the presence of bacterial porphyrin formation

NASA Astrophysics Data System (ADS)

Schleier, P.; Berndt, A.; Zinner, K.; Zenk, W.; Dietel, W.; Pfister, W.