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Last update: November 12, 2013.
1

Working Group Rosters: NCI Concise Informed Consent Template Project  

Cancer.gov

Page of 6Working Group Rosters: NCI Concise Informed Consent Template Project Role Working Group 1 (Beginning of template – background, required tests, intervention sections) Working Group 2 (Risks and benefits sections) Working Group 3 (Alternatives,

2

NCI Materials  

Cancer.gov

NCI Materials Long Island Breast Cancer Study Project Long Island Breast Cancer Study Project NCI Materials Other Materials Current Clinical Trials Related Pages Breast Cancer Home PageNCI's gateway for information

3

Design Projects in Human Anatomy & Physiology  

ERIC Educational Resources Information Center

|Very often, some type of writing assignment is required in college entry-level Human Anatomy and Physiology courses. This assignment can be anything from an essay to a research paper on the literature, focusing on a faculty-approved topic of interest to the student. As educators who teach Human Anatomy and Physiology at an urban community…

Polizzotto, Kristin; Ortiz, Mary T.

2008-01-01

4

Anatomy External [Sahuarita High School Career Curriculum Project].  

ERIC Educational Resources Information Center

|This course entitled "Anatomy External" is concerned with the dissection of the fetal pig, and is one of a series of instructional guides prepared by the teachers for the Sahuarita High School (Arizona) Career Curriculum Project. It consists of five units of study, and 13 behavioral objectives relating to these units are stated. The topics…

Esser, Robert

5

Life After Risk Models: An NCI Project to Develop a Web Site to Educate Cancer Information Seekers about Cancer Risk Concepts  

Cancer.gov

Felicia M. Solomon, MPH, OESI, NCI; Margo Michaels, MPH, OESI, NCI; and Maria Sgambati, MD, DCEG, NCI, Jalaima Graham, MPH, Children’s National Medical Center, Department of Dentistry Life After Risk Models: An NCI Project to Develop a Web Site to

6

NCI and DOD Launch Pilot Project for Coding Cancer Grants  

Cancer.gov

The National Cancer Institute (NCI) and the Department of Defense Office of Congressionally Directed Medical Research Programs (CDMRP), of the U.S. Army Medical Research and Materiel Command, announced this week the launch of a joint pilot program to test a common scientific outline.

7

Dynamic optical angiography of mouse anatomy using radial projections  

NASA Astrophysics Data System (ADS)

We demonstrate the feasibility of optical angiography on live mice using a new photoacoustic computed tomography (PCT) scanner. The scanner uses a sparse array of discrete ultrasound detectors geometrically arranged to capture 128 simultaneous radial "projections" through a 25-mm-diameter volume of interest. Denser sets of interleaved radial projections are acquired by rotating the sparse array continuously about its vertical axis during data acquisition. The device has been designed specifically for imaging laboratory mice, which remain stationary during data collection. Angiographic data are acquired at a rate of 1280 radial projections per second following a bolus injection of 2 mg/mL of indocyanine green (ICG).

Lam, Richard B.; Kruger, Robert A.; Reinecke, Daniel R.; Delrio, Stephen P.; Thornton, Michael M.; Picot, Paul A.; Morgan, Timothy G.

2010-02-01

8

Pros and cons of a group webpage design project in a freshman anatomy and physiology course.  

PubMed

To generate motivation and promote the development of written communication skills, students in a freshman-level anatomy and physiology course for nonmajors created group webpages describing historically important diseases. After the groups had been formed, each individual was assigned specific components of the disease (e.g., causes or treatments), which were subsequently combined into a final product. Interviews and questionnaires were used to document students' previous educational experiences regarding, and attitudes toward, the project. Students learned more about website design than about anatomy and physiology, but students preferred the assignment over traditional term papers. Although most students could find relevant information for this project on the internet, they were uncritical in judging the accuracy of the information they found. PMID:18057407

Crisp, Kevin M; Jensen, Murray; Moore, Randy

2007-12-01

9

Relationship of creative projects in anatomy to medical student professionalism, test performance and stress: an exploratory study  

PubMed Central

Background The anatomy course offers important opportunities to develop professionalism at an early stage in medical education. It is an academically significant course that also engenders stress in some students. Methods Over a three-year period, 115 of 297 students completed creative projects. Thirty-four project completers and 47 non-completers consented to participate in the study. Projects were analyzed for professionalism themes using grounded theory. A subset of project completers and non-completers were interviewed to determine their views about the stress of anatomy and medical school, as well as the value of the creative projects. We also compared test performance of project completers and non-completers. Results Projects completed early in the course often expressed ambivalence about anatomy, whereas later projects showed more gratitude and sense of awe. Project completers tended to report greater stress than noncompleters, but stated that doing projects reduced stress and caused them to develop a richer appreciation for anatomy and medicine. Project completers performed significantly lower than non-completers on the first written exam (pre-project). Differences between groups on individual exams after both the first and second creative project were nonsignificant. Conclusion For some students, creative projects may offer a useful way of reflecting on various aspects of professionalism while helping them to manage stress.

Shapiro, Johanna; Nguyen, Vincent P; Mourra, Sarah; Boker, John R; Ross, Marianne; Thai, Trung M; Leonard, Robert J

2009-01-01

10

Cardiac anatomy for the interventional arrhythmologist: I.terminology and fluoroscopic projections.  

PubMed

Cardiac anatomy is complex and its understanding is essential for the interventional arrhythmologist. The first difficulty is the terminology used to describe the location of sites of mapping and ablation. For many years, electrophysiologists have named these positions following the conventional electrocardiographical vocabulary, or the terminology used by surgeons performing arrhythmic surgery. This traditional nomenclature, however, failed to take note of the crucial principle of considering the location of the heart in the human body as viewed in its erect position. In other words, it had failed to use an attitudinally appropriate terminology. Almost 10 years ago, a new attitudinal nomenclature was proposed for the right and left atrioventricular junctions. In this first of a series of reviews of cardiac anatomy as seen by the interventional arrhythmologist, we discuss the role of attitudinally appropriate terminology, and relate this to the projections used for cardiac fluoroscopy, fluorography, and angiography. Throughout our series of reviews, we will illustrate the value of The Visible Human Slice and Surface Server in facilitating the understanding of the fluoroscopic anatomy. (PACE 2010; 497-507). PMID:20059709

Farré, Jerónimo; Anderson, Robert H; Cabrera, José A; Sánchez-Quintana, Damián; Rubio, José M; Benezet-Mazuecos, Juan; Del Castillo, Silvia; Macía, Ester

2009-12-31

11

NCI Spending  

Cancer.gov

NCI’s primary mission is to conduct and fund cancer research. Approximately 80 percent of the annual NCI budget is spent on cancer research at more than 650 institutions in communities across the United States and in other countries. Approximately 15 percent of the annual NCI budget is spent on cancer research conducted at NCI in Maryland. Approximately 5 percent of the annual NCI budget is spent on administration and management.

12

Characterization of apparently balanced chromosomal rearrangements from the developmental genome anatomy project.  

PubMed

Apparently balanced chromosomal rearrangements in individuals with major congenital anomalies represent natural experiments of gene disruption and dysregulation. These individuals can be studied to identify novel genes critical in human development and to annotate further the function of known genes. Identification and characterization of these genes is the goal of the Developmental Genome Anatomy Project (DGAP). DGAP is a multidisciplinary effort that leverages the recent advances resulting from the Human Genome Project to increase our understanding of birth defects and the process of human development. Clinically significant phenotypes of individuals enrolled in DGAP are varied and, in most cases, involve multiple organ systems. Study of these individuals' chromosomal rearrangements has resulted in the mapping of 77 breakpoints from 40 chromosomal rearrangements by FISH with BACs and fosmids, array CGH, Southern-blot hybridization, MLPA, RT-PCR, and suppression PCR. Eighteen chromosomal breakpoints have been cloned and sequenced. Unsuspected genomic imbalances and cryptic rearrangements were detected, but less frequently than has been reported previously. Chromosomal rearrangements, both balanced and unbalanced, in individuals with multiple congenital anomalies continue to be a valuable resource for gene discovery and annotation. PMID:18319076

Higgins, Anne W; Alkuraya, Fowzan S; Bosco, Amy F; Brown, Kerry K; Bruns, Gail A P; Donovan, Diana J; Eisenman, Robert; Fan, Yanli; Farra, Chantal G; Ferguson, Heather L; Gusella, James F; Harris, David J; Herrick, Steven R; Kelly, Chantal; Kim, Hyung-Goo; Kishikawa, Shotaro; Korf, Bruce R; Kulkarni, Shashikant; Lally, Eric; Leach, Natalia T; Lemyre, Emma; Lewis, Janine; Ligon, Azra H; Lu, Weining; Maas, Richard L; MacDonald, Marcy E; Moore, Steven D P; Peters, Roxanna E; Quade, Bradley J; Quintero-Rivera, Fabiola; Saadi, Irfan; Shen, Yiping; Shendure, Jay; Williamson, Robin E; Morton, Cynthia C

2008-03-01

13

Characterization of Apparently Balanced Chromosomal Rearrangements from the Developmental Genome Anatomy Project  

PubMed Central

Apparently balanced chromosomal rearrangements in individuals with major congenital anomalies represent natural experiments of gene disruption and dysregulation. These individuals can be studied to identify novel genes critical in human development and to annotate further the function of known genes. Identification and characterization of these genes is the goal of the Developmental Genome Anatomy Project (DGAP). DGAP is a multidisciplinary effort that leverages the recent advances resulting from the Human Genome Project to increase our understanding of birth defects and the process of human development. Clinically significant phenotypes of individuals enrolled in DGAP are varied and, in most cases, involve multiple organ systems. Study of these individuals' chromosomal rearrangements has resulted in the mapping of 77 breakpoints from 40 chromosomal rearrangements by FISH with BACs and fosmids, array CGH, Southern-blot hybridization, MLPA, RT-PCR, and suppression PCR. Eighteen chromosomal breakpoints have been cloned and sequenced. Unsuspected genomic imbalances and cryptic rearrangements were detected, but less frequently than has been reported previously. Chromosomal rearrangements, both balanced and unbalanced, in individuals with multiple congenital anomalies continue to be a valuable resource for gene discovery and annotation.

Higgins, Anne W.; Alkuraya, Fowzan S.; Bosco, Amy F.; Brown, Kerry K.; Bruns, Gail A.P.; Donovan, Diana J.; Eisenman, Robert; Fan, Yanli; Farra, Chantal G.; Ferguson, Heather L.; Gusella, James F.; Harris, David J.; Herrick, Steven R.; Kelly, Chantal; Kim, Hyung-Goo; Kishikawa, Shotaro; Korf, Bruce R.; Kulkarni, Shashikant; Lally, Eric; Leach, Natalia T.; Lemyre, Emma; Lewis, Janine; Ligon, Azra H.; Lu, Weining; Maas, Richard L.; MacDonald, Marcy E.; Moore, Steven D.P.; Peters, Roxanna E.; Quade, Bradley J.; Quintero-Rivera, Fabiola; Saadi, Irfan; Shen, Yiping; Shendure, Jay; Williamson, Robin E.; Morton, Cynthia C.

2008-01-01

14

NCI Designated Cancer Centers  

MedlinePLUS

... en español NCI Highlights The Nation's Investment in Cancer Research: 2013 NCI Funded Research Portfolio Report to the ... to Drop Interactive NCI Budget Analysis Tool Global Cancer Research Programs NCI-Designated Cancer Centers NCI-designated cancer ...

15

Humanities in Gross Anatomy Project: A Novel Humanistic Learning Tool at Des Moines University  

ERIC Educational Resources Information Center

|Gross anatomy affords physical therapy students an opportunity to discover human morphology by intimately studying the dead. Moreover, it also exposes future physical therapists to the humanistic aspects of the profession. In 2007, anatomy faculty decided to socialize students to the humanities with a new course requirement: Humanities in Gross…

Canby, Craig A.; Bush, Traci A.

2010-01-01

16

Project Pathogens: The Anatomy of Omission Errors in Construction and Resource Engineering Project  

Microsoft Academic Search

Construction and engineering projects are typically complex in nature and are prone to cost and schedule overruns. A significant factor that often contributes to these overruns is rework. Omissions errors, in particular, have been found to account for as much as 38% of the total rework costs experienced. To date, there has been limited research that has sought to determine

Peter E. D. Love; David J. Edwards; Zahir Irani; Derek H. T. Walker

2009-01-01

17

NCI Community Cancer Centers Program  

Cancer.gov

NCI Community Cancer Centers Program NCCCP Program Advisory Committee 1 Maureen Johnson, PhD Norman Coleman, MD NCCCP Project Officer Special Advisor Special Assistant to the Director Radiation Oncology Branch, NIH 31 Center Drive

18

NCI Launches Biorepository for Prostate Cancer  

Cancer.gov

NCI today announced a cancer biorepository pilot project designed to standardize biospecimen collection and management among investigators of the NCI's prostate cancer Specialized Programs of Research Excellence. The project will enhance the quality and availability of various biospecimens and associated data for the broader scientific community.

19

Anatomy Digital Storytelling Projects 101: How to Create and Implement Digital Storytelling into Your Curriculum  

NSDL National Science Digital Library

A description of a digital storytelling project; allowing students to gather and process information relating to a physiology concept and develop a digital storytelling project explaining and demonstrating said concept.

2008-12-01

20

Links to NCI Materials  

Cancer.gov

Updated: 02/02/2011 Updated: 02/02/2011 Links to NCI Materials The Breast Cancer Prevention Trial Introduction Links to NCI Materials BCPT Publications Related Pages Search for Clinical TrialsNCI's List of Cancer Clinical

21

68 FR 34405 - Proposed Collection; Comment Request; NCI Cancer Information Service Demographic/Customer Service...  

Federal Register 2010, 2011, 2012, 2013

...Proposed Collection; Comment Request; NCI Cancer Information Service Demographic/Customer...data collection projects, the National Cancer Institute (NCI), the National Institutes...Proposed Collection: Title: The National Cancer Institute Cancer Information Service...

2003-06-09

22

Availability of research funds for NCI’s Provocative Questions project announced  

Cancer.gov

NCI’s Provocative Questions project has announced that it is now seeking applications from researchers eager to influence the state of cancer research by tackling potentially game-changing, but perplexing, scientific questions that could drive progress against cancer. The grants will support research projects using sound and innovative research strategies to solve specific problems and paradoxes in cancer research.

23

Anatomy and Forebrain Projections of the Olfactory and Vomeronasal Organs in Axolotls (Ambystoma mexicanum) (Part 2 of 2)  

Microsoft Academic Search

We examined the anatomy of the nasal cavity and forebrain in the axolotl (Ambystoma mexicanum) to determine whether the olfactory and vomeronasal systems are present in this neotenic aquatic salamander. The current study was motivated by two considerations: (a) little is known of the anatomy of the vomeronasal system in aquatic vertebrates, and (b) the presence of both olfactory and

Heather L. Eisthen; Dale R. Sengelaub; Dolores M. Schroeder; Jeffrey R. Alberts

1994-01-01

24

Anatomy and Forebrain Projections of the Olfactory and Vomeronasal Organs in Axolotls (Ambystoma mexicanum) (Part 1 of 2)  

Microsoft Academic Search

We examined the anatomy of the nasal cavity and forebrain in the axolotl (Ambystoma mexicanum) to determine whether the olfactory and vomeronasal systems are present in this neotenic aquatic salamander. The current study was motivated by two considerations: (a) little is known of the anatomy of the vomeronasal system in aquatic vertebrates, and (b) the presence of both olfactory and

Heather L. Eisthen; Dale R. Sengelaub; Dolores M. Schroeder; Jeffrey R. Alberts

1994-01-01

25

Students as resurrectionists--A multimodal humanities project in anatomy putting ethics and professionalism in historical context.  

PubMed

Because medical students have many different learning styles, the authors, medical students at Mayo Clinic, College of Medicine researched the history of anatomical specimen procurement, reviewing topic-related film, academic literature, and novels, to write, direct, and perform a dramatization based on Robert Louis Stevenson's The Body-Snatcher. Into this performance, they incorporated dance, painting, instrumental and vocal performance, and creative writing. In preparation for the performance, each actor researched an aspect of the history of anatomy. These micro-research projects were presented in a lecture before the play. Not intended to be a research study, this descriptive article discusses how student research and ethics discussions became a theatrical production. This addition to classroom and laboratory learning addresses the deep emotional response experienced by some students and provides an avenue to understand and express these feelings. This enhanced multimodal approach to"holistic learning" could be applied to any topic in the medical school curriculum, thoroughly adding to the didactics with history, humanities, and team dynamics. PMID:20827724

Hammer, Rachel R; Jones, Trahern W; Hussain, Fareeda Taher Nazer; Bringe, Kariline; Harvey, Ronee E; Person-Rennell, Nicole H; Newman, James S

26

The anatomy of learning anatomy.  

PubMed

The experience of clinical teachers as well as research results about senior medical students' understanding of basic science concepts has much been debated. To gain a better understanding about how this knowledge-transformation is managed by medical students, this work aims at investigating their ways of setting about learning anatomy. Second-year medical students were interviewed with a focus on their approach to learning and their way of organizing their studies in anatomy. Phenomenographic analysis of the interviews was performed in 2007 to explore the complex field of learning anatomy. Subjects were found to hold conceptions of a dual notion of the field of anatomy and the interplay between details and wholes permeated their ways of studying with an obvious endeavor of understanding anatomy in terms of connectedness and meaning. The students' ways of approaching the learning task was characterized by three categories of description; the subjects experienced their anatomy studies as memorizing, contextualizing or experiencing. The study reveals aspects of learning anatomy indicating a deficit in meaningfulness. Variation in approach to learning and contextualization of anatomy are suggested as key-elements in how the students arrive at understanding. This should be acknowledged through careful variation of the integration of anatomy in future design of medical curricula. PMID:19551482

Wilhelmsson, Niklas; Dahlgren, Lars Owe; Hult, Håkan; Scheja, Max; Lonka, Kirsti; Josephson, Anna

2009-06-24

27

Students as ResurrectionistsÃÂA Multimodal Humanities Project in Anatomy Putting Ethics and Professionalism in Historical Context  

NSDL National Science Digital Library

This article describes an experiential learning opportunity in the medical school setting to integrate history, theatre, and anatomy. This article describes the integration of medical students into theatre, requiring students to research anatomical history.

2010-09-01

28

Analysis of Exposure to NCI's (National Cancer Institute's) Cancer Prevention Awareness PSAs (Public Service Announcements). Executive Summary.  

National Technical Information Service (NTIS)

The project analyzed the exposure of six public service announcements (PSAs) distributed on three waves during Phase 1 of the National Cancer Institute's (NCI) Cancer Prevention Awareness Program. All NCI spots were monitored for a 21-month period beginni...

V. S. Freimuth S. L. Hammond

1986-01-01

29

NCI Meetings and Workshops  

Cancer.gov

U.S.-Mexico Cytogenetics Laboratory Standardization ProjectApril 7-8, 2011Mexico City, MexicoThis workshop included site visits and a one-day workshop with institutions and laboratories located near Mexico City to determine the current state-of-the-science and to introduce a pilot program for the standardization of cytogenetics testing, reporting, and review. The workshop was co-organized by NCI, American Society of Hematology (ASH), and Agrupación Mexicana para el Estudio de la Hematología (AMEH).

30

Sinus Anatomy  

MedlinePLUS

Sinus Anatomy Rakesh Chandra, MD INTRODUCTION The paranasal sinuses (“the sinuses”) are air-filled cavities located within the bones ... tube responsible for clearing air pressure in the ears; it opens into the backside wall of the ...

31

NCI Interactive Budget Analysis Tool  

Cancer.gov

This tool provides users an interactive overview of the National Cancer Institute (NCI) budget and Fact Book data since Fiscal Year 1999. Additional historical NCI budget information can be obtained through the NCI Fact Book Collection.

32

NCI's Role in International Collaboration  

Cancer.gov

NCI's Role in International Collaboration NCI Programs and Offices NCI Meetings and Workshops International Collaboration in Clinical Trials Collaborate with U.S.-Based Research Groups Get Answers to Common Questions About...

33

Instant Anatomy  

NSDL National Science Digital Library

Created by Professor Robert Whitaker, this website was designed to teach medical students about anatomy. Visitors to the site will find a range of materials, including diagrams, illustrations, quizzes, tips, mnemonics, and so on. On the homepage, visitors will find a What's New area, which includes podcasts that deal with subjects such as the small muscles of the hand and the anatomy of the posterior forearm. Other sections on the homepage include Head & Neck, Thorax, Abdomen, Arm, and Leg. Each of these sections includes dozens of illustrations, along with some useful Brain Training Games. These games are designed to increase comprehension of the materials covered in each area. Moving on, the Lectures area includes talks such as "Parasympathetic Supply of the Head," "Cortical Control of Cranial Nerves," and several others. The site is rounded out by a collection of iPhone and iPad apps, along with a set of detailed flash cards.

Whitaker, Andrew

2012-06-01

34

Instant Anatomy  

NSDL National Science Digital Library

Dr Robert Whitaker, a professor at Cambridge University, creates this podcast covering anatomy. Intended as a tool for medical students and students in related fields, these podcasts are both entertaining and educational. Elucidated topics include the abdominal wall, the axilla and cubital fossa, and cranial nerves - to name a few. This collection will be useful for medical students, nurses, scientists, and medical assistants, among others.

Whitaker, Robert

2008-02-12

35

NCI-Frederick Laboratory Animal Science Program  

Cancer.gov

The services of LASP laboratories and facilities may be accessed using the "Yellow Task Request System" and Accessions System. These web-based systems enable investigators to request services and obtain cost and time estimates for each project. NCI approval is an integral function of these processes, which ensures that adequate funding and other resources are available to perform the work.

36

NCI Shady Grove Now Open  

Cancer.gov

NCI’s new location, NCI Shady Grove, is open at 9609 Medical Center Drive in Rockville, MD. While NCI's clinical program remains on the NIH campus in Bethesda, NCI Shady Grove will accommodate approximately 2,450 administrative and program staff who previously occupied Executive Plaza and Helgerman Court buildings in Rockville. Offices at NCI started moving into the new building in December 2012 and the move will be completed within six months.

37

For NCI Employees & Staff  

Cancer.gov

For NCI Employees & Staff Report an Emergency NIH Bethesda (Main) Campus: From an office phone: 911 From a cell phone: (301)496-9911 Off Campus: From an office phone: 9-911 From a cell phone: 911 Please visit MyNCI.cancer.gov for detailed information

38

NCI Banner and Minibanner  

Cancer.gov

Updated: 05/03/2012 Updated: 05/03/2012 NCI Banner and Minibanner Banner for NCI's Main Website "National Cancer Institute" Text: Univers 57 Condensed, 28pt "at the National Institutes of Health" Text: Univers Regular 11pt for "at the" and 13pt "National

39

Anatomy and projection patterns of the superior olivary comlex in the mexican free-tailed bat, Tadarida brasiliensis mexicana  

Microsoft Academic Search

The superior olivary complex (SOC) is the first station in the ascending auditory pathway that receives binaural projections. Two of the principal nuclei, the lateral superior olive (LSO) and the medial superior olive (MSO), are major sources of ascending projections to the inferior colliculus. Whereas almost all mammals have an LSO, it has traditionally been thought that only animals that

Benedikt Grothe; Hermann Schweizer; George D. Pollak; Gerd Schuller; Christina Rosemann

2004-01-01

40

Anatomy Arcade  

NSDL National Science Digital Library

Anatomy truly gets interactive via these collection of fun and engaging games, videos, and other multimedia excursions. The site was created by Ben Crossett, a science teacher in Australia. Several years ago, he decided to craft some new resources like "Poke a Muscle" and "Whack-A-Bone" that would be both entertaining and educational. Visitors can look at the Games By Body System to get started, or they can also look over the Games By Type area. The types of games here include jigsaw puzzles, crosswords, word searches, and the nice catch all Just For Fun. The activities are also made interesting by the mere fact that they contain catchy visuals and jaunty tunes. The site also includes a place where teachers can offer feedback and an area just for students.

Crossett, Ben

41

Anatomy and projection patterns of the superior olivary complex in the Mexican free-tailed bat, Tadarida brasiliensis mexicana.  

PubMed

The superior olivary complex (SOC) is the first station in the ascending auditory pathway that receives binaural projections. Two of the principal nuclei, the lateral superior olive (LSO) and the medial superior olive (MSO), are major sources of ascending projections to the inferior colliculus. Whereas almost all mammals have an LSO, it has traditionally been thought that only animals that hear low frequencies have an MSO. Recent reports, however, suggest that the medial part of the SOC in bats is highly variable and that at least some bats have a well-developed MSO. Thus, the main goal of this study was to evaluate the cytoarchitecture and connections of the principal superior olivary nuclei of the Mexican free-tailed bat, with specific attention directed at the MSO. Cell and fiber stained material revealed that the LSO and the medial nucleus of the trapezoid body (MNTB) are similar to those described for other mammals. There are two medial nuclei we refer to as dorsomedial periolivary nucleus (DMPO) and MSO. Tracer experiments exhibited that the DMPO receives bilateral projections from the cochlear nucleus, and additional projections from the ipsilateral MNTB. The DMPO sends a strong projection to the ipsilateral inferior colliculus. Positive staining for acetylcholinesterase indicates that the DMPO is a part of the olivocochlear system, as it is in other animals. The MSO in the free-tailed bat meets many of the criteria that traditionally define this nucleus. These include the presence of bipolar and multipolar principal cells, bilateral innervation from the cochlear nucleus, a strong projection from the ipsilateral MNTB, and the absence of cholinergic cells. The major difference from traditional MSO features is that it projects bilaterally to the inferior colliculus. Approximately 30% of its cells provide collateral projections to the colliculi on both sides. Functional implications of the MSO for the free-tailed bat are considered in the Discussion. PMID:8034792

Grothe, B; Schweizer, H; Pollak, G D; Schuller, G; Rosemann, C

1994-05-22

42

Governance — CBIIT: Welcome to the NCI Center for Biomedical Informatics and Information Technology  

Cancer.gov

Established in mid-2011 by the NCAB, the IWG is charged with providing strategic guidance and direction on NCI informatics investments that support the Institute’s scientific goals. The IWG provides a venue for identifying high-priority biomedical informatics needs, harmonizing ongoing and proposed informatics projects across NCI programs, both intramural and extramural, and reducing redundancies wherever possible.

43

71 FR 46486 - Proposed Collection; Comment Request; Pre-Testing of NCI Communication Messages  

Federal Register 2010, 2011, 2012, 2013

...of NCI Communication Messages SUMMARY: In compliance...public comment on proposed data collection projects...of NCI Communication Messages. Type of Information...2) produce or refine messages that have the greatest...obtain a copy of the data collection plans...

2006-08-14

44

A SEX COMPARISON OF THE ANATOMY AND FUNCTION OF THE MAIN OLFACTORY BULB-MEDIAL AMYGDALA PROJECTION IN MICE  

PubMed Central

We previously reported that some main olfactory bulb (MOB) mitral/tufted (M/T) cells send a direct projection to the ‘vomeronasal’ amygdala in female mice and selectively respond to volatile male mouse urinary odors. We asked whether MOB M/T cells that project to the vomeronasal amygdala exist in male mice and whether there is a sexually dimorphic response of these neurons to volatile male urinary pheromones. Gonadectomized male and female mice received bilateral injections of the retrograde tracer, Cholera toxin-B (CTb) into the medial amygdala (Me), which is part of the vomeronasal amygdala. All subjects were then treated with estradiol benzoate and progesterone before being exposed to volatile male urinary odors whereupon they were sacrificed 90 min later. Sections of the MOB were immunostained for Fos protein and/or CTb. Male mice, like females, displayed a small population of MOB M/T cells that project to the Me. While the general localization of these cells was similar in the two sexes, there were statistically significant sex differences in the percentage of MOB M/T cells in the anterior and posterior medial segments of the MOB that were retrogradely labeled by CTb. Male urinary volatiles stimulated equivalent, significant increases in Fos expression by MOB M/T neurons projecting to the Me in the two sexes. By contrast, in the same mice exposure to male urinary volatiles stimulated a significant increase in Fos expression by mitral cells in the accessory olfactory bulb (AOB) only in female subjects. Thus any sexually dimorphic behavioral or neuroendocrine responses to male urinary volatiles likely depend on the differential processing of these odor inputs in the AOB and/or other downstream forebrain structures after their detection by the main olfactory system.

Kang, Ningdong; McCarthy, Elizabeth A.; Cherry, James A.; Baum, Michael J.

2010-01-01

45

NCI Division of Extramural Activities  

Cancer.gov

The paramount goal of the National Cancer Institute (NCI) is to develop the knowledge base that will ultimately lessen the impact of cancer. Among the most important contributors to this base are the outstanding extramurally funded scientists supported by the NCI through grants, contracts, and cooperative agreements. The DEA was established within the NCI to provide the NCI and the scientific community with expert scientific review of the merits of extramural research, procedures, and policies to help the Institute achieve its goal.

46

NCI at Frederick: Cytogenetics  

Cancer.gov

The Comparative Molecular Cytogenetic Core provides molecular cytogenetic support services to the NCI community. This core facilitates the assessment of structural and numerical genomic changes in cancer, pre-cancer, and cancer models.

47

NCI at Frederick: Events  

Cancer.gov

The NCI at Frederick provides conference support for programs that fall within the Federally Funded Research and Development Center (FFRDC), Operations and Technical Support (OTS) contractor’s statement of work.

48

NCI Special Notes  

Cancer.gov

The NCI K24 award provides support and "protected time" from clinical duties to Associate-level clinician-scientists to expand their cancer-focused patient-oriented research and mentor junior clinicians in patient-oriented research.

49

Links to NCI Materials  

Cancer.gov

High-dose chemotherapy with bone marrow or stem cell transplantation for the treatment of advanced and early-stage breast cancer has been tested in several large, randomized clinical trials sponsored by the NCI, as well as in trials done in other countries. In all of the NCI-sponsored randomized trials, and in most of the international ones, high-dose chemotherapy with transplantation has not proven superior to treatment with more standard doses of chemotherapy.

50

Programs and Projects  

Cancer.gov

Programs and Projects PREVENT Cancer Drug Development Program Clinical Trials of Chemoprevention Agents Chemoprevention Agent Development Research Portfolio Search the NCI-Funded Research Portfolio for projects supported by the Chemoprevention Agent

51

Programs and Projects  

Cancer.gov

Programs and Projects Lung and Upper Aerodigestive Cancers Research Group Research Portfolio Search the NCI-Funded Research Portfolio for projects supported by the Lung and Upper Aerodigestive Cancer Research Group. Use the Advanced Search to choose Division

52

The NCI SBIR Program - Presented at AACR  

Cancer.gov

The NCI SBIR Program Presentation at AACR Michael Weingarten Director, NCI SBIR Development Center - April 20, 2009 Todays Presentation Program Overview NCI Funding Opportunities New SBIR Bridge Aw ard Tips on Submitting Applications Overview

53

NCI Community Cancer Centers Program - NCCCP Homepage  

Cancer.gov

NCI Community Cancer Centers Program - NCCCP Homepage Media Center Overview Contact information Quick Links Note from the NCI Director Participating Pilot Sites FAQ Contact Information Contact Information Contacts - NCI Office

54

NCI/CPFP - 2010 Application Catalog - Preceptorships  

Cancer.gov

Preceptorships are selected through a matching process. During their first summer onsite at NCI, fellows spend time meeting with potential preceptors. A mutual agreement is reached between the preceptor and the fellow on the research that will be completed during the fellowship. A research proposal for the initial project is then prepared for approval by the preceptor and the CPFP scientific staff. Whereas the CPFP has all administrative responsibility for each fellow, the preceptor provides scientific supervision.

55

Development, Assessment and Validation of Virtual Reality for Human Anatomy Instruction.  

National Technical Information Service (NTIS)

This research project seeks to meet the objective of science training by developing, assessing, validating and utilizing VR as a human anatomy training medium. Current anatomy instruction is primarily in the form of lectures and usage of textbooks. In ide...

K. B. Marshall

1996-01-01

56

NCI CCOP book!  

Cancer.gov

Former NCI Director Vincent DeVita, M.D. EVENT DATE December 1971 President Nixon signs the National Cancer Act (P.L. 92-218), which increases responsibilities for the NCI director; initiates the National Cancer Program. This act establishes the President’s Cancer Panel, the National Cancer Advisory Board, 15 research, training, and demonstration cancer centers, cancer control programs for cooperation with state and other health agencies to diagnose, prevent, and treat cancer, and extensive data collection, analysis, and dissemination efforts.

57

NCI: SBIR & STTR - Investor Forum  

Cancer.gov

The National Cancer Institute (NCI) Small Business Innovation Research (SBIR) program hosted the 2012 NCI SBIR Investor Forum on April 18, 2012 in Santa Clara, CA. This year’s meeting brought together nearly 200 SBIR-funded companies, investors, venture capitalists, strategic partners, and business leaders from the biotech and pharmaceutical industries, and featured presentations from 18 top NCI SBIR-funded companies with innovative cancer-related technologies on the brink of commercialization.

58

Of mice and men: aligning mouse and human anatomies.  

PubMed

This paper reports on the alignment between mouse and human anatomies, a critical resource for comparative science as diseases in mice are used as mod-els of human disease. The two ontologies under investigation are the NCI Thesaurus (human anatomy) and the Adult Mouse Anatomical Dictionary, each comprising about 2500 anatomical concepts. This study compares two approaches to aligning ontologies. One is fully automatic, based on a combination of lexical and structural similarity; the other is manual. The resulting mappings were evaluated by an expert. 715 and 781 mappings were identified by each method respectively, of which 639 are common to both and all valid. The applications of the map-ping are discussed from the perspective of biology and from that of ontology. PMID:16779002

Bodenreider, Olivier; Hayamizu, Terry F; Ringwald, Martin; De Coronado, Sherri; Zhang, Songmao

2005-01-01

59

Of Mice and Men: Aligning Mouse and Human Anatomies  

PubMed Central

This paper reports on the alignment between mouse and human anatomies, a critical resource for comparative science as diseases in mice are used as models of human disease. The two ontologies under investigation are the NCI Thesaurus (human anatomy) and the Adult Mouse Anatomical Dictionary, each comprising about 2500 anatomical concepts. This study compares two approaches to aligning ontologies. One is fully automatic, based on a combination of lexical and structural similarity; the other is manual. The resulting mappings were evaluated by an expert. 715 and 781 mappings were identified by each method respectively, of which 639 are common to both and all valid. The applications of the mapping are discussed from the perspective of biology and from that of ontology.

Bodenreider, Olivier; Hayamizu, Terry F.; Ringwald, Martin; De Coronado, Sherri; Zhang, Songmao

2005-01-01

60

NCI Director's Awards 2008  

Cancer.gov

INDIVIDUAL AWARDS Lawrence J. Ray, J.D. For exceptional leadership and service to the Office of Management for the implementation of new procedures and reorganization constructing a vitalized and effective administrative operation. James H. Doroshow, M.D. Provided leadership for NCI’s early drug discovery and development, and transforming clinical cancer research across the entire spectrum of therapeutic oncology.

61

NCI Visuals Online: Search  

Cancer.gov

Skip Navigation NCI Visuals Online Home About My Pictures Browse Search Quick Search Search Search for: Date Created: Any 1900 1920 1940 1960 1980 1990 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 to Any 1900 1920 1940 1960 1980 1990 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 Sort

62

The NCI SBIR Program  

Cancer.gov

The NCI SBIR Program How to Apply Tips for Preparing and Submitting an Application What Does it Take to Get Funded? • SBIR/STTRs are highly competitive • There is a big gap between being “funded” and being “almost funded” • Solution: Prepare

63

NCI Mouse Repository  

Cancer.gov

The NCI Mouse Repository cryoarchives and distributes strains of genetically engineered mice that are of immediate interest to the cancer research community. These are either gene-targeted or transgenic mice that display a cancer-related phenotype, or "tool strains" (e.g., cre transgenics) that can be used to develop new cancer models.

64

NCI at Frederick: Downloads  

Cancer.gov

To better serve our users, we have compiled a list of useful software when using the NCI at Frederick web site. Keeping the software on your computer current is essential for being able to experience all that the Frederick National Lab web site has to offer. All of the resources below are available free of charge for everyone to use.

65

NCI Cancer Bulletin for June 26, 2007 (HTML)  

Cancer.gov

NCI has launched the pilot phase of its Community Cancer Centers Program (NCCCP), an initiative that aims to bring the latest advances in cancer care to patients where they live. The project will focus on underserved communities and groups that are disproportionately affected by the disease.

66

Anatomy: Spotlight on Africa  

ERIC Educational Resources Information Center

|Anatomy departments across Africa were surveyed regarding the type of curriculum and method of delivery of their medical courses. While the response rate was low, African anatomy departments appear to be in line with the rest of the world in that many have introduced problem based learning, have hours that are within the range of western medical…

Kramer, Beverley; Pather, Nalini; Ihunwo, Amadi O.

2008-01-01

67

ANATOMY OF THE CLITORIS  

Microsoft Academic Search

PurposeWe present a comprehensive account of clitoral anatomy, including its component structures, neurovascular supply, relationship to adjacent structures (the urethra, vagina and vestibular glands, and connective tissue supports), histology and immunohistochemistry. We related recent anatomical findings to the historical literature to determine when data on accurate anatomy became available.

HELEN E. O'CONNELL; KALAVAMPARA V. SANJEEVAN; JOHN M. HUTSON

2005-01-01

68

NCI Mouse Repository - Available Strains  

Cancer.gov

The following strains are currently being distributed from the NCI Mouse Repository. Please note that only breeder pairs are available. Visit the ordering information page for more information on the process of ordering mouse models from the NCI Mouse Repository. Click on the common strain name to view details on that strain. You can sort on selected columns by clicking on the column title.

69

NCCCP Guide to NCI Resources  

Cancer.gov

NCI Community Cancer Centers Program Guide to NCI Resources The National Cancer Institute is committed to making progress against different cancer types through varied approaches. To this end, it develops, funds, and disseminates a vast array of programs, materials, and resources.

70

Directions to NCI-Frederick:  

Cancer.gov

Directions to NCI-Frederick: NCI-Frederick is located within the Fort Detrick U.S. Army facility in Frederick, Maryland. Please be aware that you will be asked to provide Fort Detrick security with two Government issued picture identifiers before

71

Applied peritoneal anatomy.  

PubMed

The peritoneal cavity is a complex anatomical structure with multiple attachments and connections. These are better understood with reference to the embryological development of this region. Armed with this knowledge, the diagnosis and assessment of a wide range of common intra-abdominal diseases becomes straightforward. This article will review and simplify the terminology, complex embryological development, and anatomy of the peritoneum, peritoneal attachments, and the reflections forming the peritoneal boundaries. Normal anatomy will be described using schematic diagrams with corresponding computed tomography (CT) and magnetic resonance imaging (MRI) images, including CT peritoneograms. The relevance of intra- and extra-peritoneal anatomy to common pathological processes will be demonstrated. PMID:23149392

Patel, R R; Planche, K

2012-11-10

72

NCI Visuals Online: About  

Cancer.gov

The National Cancer Institute's (NCI) Visuals Online provides a range of photographs and illustrations that may help communicators of medical and public health convey meaning, describe concepts, and tell stories. The collection spans everything from biomedical, science, and patient-care related illustrations and images to portraits of present and past directors and the staff of the National Cancer Institute. Visuals Online currently provides public access to 2,785 images.

73

Pathological Anatomy of Complications.  

National Technical Information Service (NTIS)

A number of papers in the recent literature have been concerned with various aspects of the pathogenesis of retinal detachment. Little has been written, however, about the pathological anatomy of the eye after operations for reattachment of the retina. In...

M. Boniuk L. E. Zimmerman

1965-01-01

74

Pearl Millet Anatomy.  

National Technical Information Service (NTIS)

The literature on pearl millet (Pennisetum americanum Pennisetum typhoides) anatomy is limited. It is scattered in a variety of studies, most of which lack adequate illustration. Only two general descriptions are known to the authors. The present study is...

R. K. Maiti S. S. Bisen

1979-01-01

75

An Overview of the NCI SBIR Program  

Cancer.gov

An Overview of the NCI SBIR Program Michael Weingarten Director, NCI SBIR Development Center September 9, 2008 Todays Presentation Overview Eligibility Requirements Move to More Focused Solicitations New SBIR Bridge Award Submitting An Application

76

NCI-Frederick PHL - Pathology  

Cancer.gov

PHL pathologists function as scientific collaborators assisting in animal study design, species selection, histopathology and immunohistopathology evaluation, photomicrography, report and manuscript preparation. This is in keeping with NCI-Frederick's research mission.

77

NCI-Designated Cancer Centers  

Cancer.gov

NCI’s 67 Designated Cancer Centers form a nationwide network for studying and controlling cancer. The Centers are the primary source of new discoveries into cancer’s causes, prevention, diagnosis, and treatment.

78

NCI Community Cancer Centers Program  

MedlinePLUS

... found at USA.gov . The National Cancer Institute Community Cancer Centers Program (NCCCP) is a public-private ... National Cancer Institute (NCI) and a network of community hospital-based cancer centers from around the United ...

79

NCI at Frederick: Student Programs  

Cancer.gov

The National Cancer Institute (NCI), part of the National Institutes of Health (NIH), offers a variety of internship programs to students, starting in high school. There are summer positions as well as part-time, year-round internships that provide high-school students and college undergraduates with the opportunity to work in an NCI research lab. Visit the links below to learn more about specific programs and awards and how to apply.

80

Project Enlists Community Physicians in Cancer Research  

Cancer.gov

To enable more patients and physicians to participate in clinical studies that advance cancer care, the National Cancer Institute (NCI) is conducting a pilot project, the Expanded Participation Project (EPP), to speed cancer research by broadening access to clinical trials

81

[Anatomy of the liver].  

PubMed

Over the past decades, great progress has been made in surgery on the liver. Technical achievements and the strict application of anatomical knowledge to surgical practice have added a new dimension to the field of liver surgery. In some cases, new facts about the anatomy of the liver needed considerable time before being implemented. Surgery of liver metastases, primary tumours of the liver and not least liver transplantation have focussed the interest of visceral surgeons more and more on this organ. Segment-orientated liver anatomy, a knowledge and consideration of vascular structures, and the observance of anatomical landmarks are the prerequisites for successful surgery on the liver. PMID:10960965

Scheuerlein, H; Köckerling, F

2000-01-01

82

Illustrated Speech Anatomy.  

ERIC Educational Resources Information Center

Written for students in the fields of speech correction and audiology, the text deals with the following: structures involved in respiration; the skeleton and the processes of inhalation and exhalation; phonation and pitch, the larynx, and esophageal speech; muscles involved in articulation; muscles involved in resonance; and the anatomy of the…

Shearer, William M.

83

Anatomy for Biomedical Engineers  

ERIC Educational Resources Information Center

|There is a perceived need for anatomy instruction for graduate students enrolled in a biomedical engineering program. This appeared especially important for students interested in and using medical images. These students typically did not have a strong background in biology. The authors arranged for students to dissect regions of the body that…

Carmichael, Stephen W.; Robb, Richard A.

2008-01-01

84

NCI Funded Research Portfolio - ZIA CP010182-01030 Detail  

Cancer.gov

This follows about 60,000 women who were former participants in the joint NCI and ACS Breast Cancer Detection Demonstration Project (BCDDP), a nationwide breast cancer screening program conducted during the 1970s. The follow-up started in 1980, with ascertainment of cancer and mortality continuing through 1998. The BCDDP Follow-up Study is particularly valuable for ascertaining the risks and benefits of menopausal hormone replacement therapy associated with cancers of the breast and colon.

85

Web-Based, Cross-Group Registration for Clinical Trials Piloted for NCI's Cooperative Group Members Cancer Trial Support Unit Could Expand to Other Physicians in 2001  

Cancer.gov

Oncologists who belong to the National Cancer Institute's (NCI's) Cooperative Groups can now register online for selected phase III studies in a pilot project intended to streamline and simplify many of the tasks associated with clinical trials.

86

The anatomy workbook  

SciTech Connect

This is an atlas of human anatomy presented in the form of line drawings, many of which correspond to imaging planes used in ultrasound (US), computed tomography (CT), and magnetic resonance (MR). The book is organized into 17 sections, each covering a specific structure or organ system. Large, uncluttered drawings are labeled for identification of structures of interest. Many illustrations include captions consisting of comments explaining major divisions within organs, specific anatomic relationships and landmarks, and pertinent vascular anatomy. Most organs are first depicted in isolation or in relation to important adjacent organs or blood vessels and are rendered as if viewed from anterior, posterior, inferior, or superior perspectives. The organs are demonstrated again in serial transverse, saggital, and coronal sections, each accompanied by a drawing of a body in anatomic position denoting the plane of the section.

Hagen-Ansert, S.L.

1986-01-01

87

NCI-Frederick FACILITY - Overview  

Cancer.gov

FACILITY is a data management system created by Locus Technology, Inc. that is currently being utilized by the Laboratory Animal Sciences Program to automate the management of animal inventory, billing, technical charges, animal study proposals, and training records for all NCI-Frederick and Bethesda animal facility locations. LASP is currently working with interested investigators, at NCI-Frederick, to expand the capabilities of FACILITY by using the system to track individual animal data, breeding colony data, as well as experimental and study data.

88

Anatomy and radiological anatomy of the lumbar radicular canals  

Microsoft Academic Search

Summary The radicular canal is the lateral portion of the spinal canal when it is trefoil. It is a bony and ligamentary, monovertebral and indeformable space, the measurements of which are reproducible. The anatomy of this radicular canal has been studied in the whole of the lumbar vertebrae of 50 anatomical subjects. Its radiological anatomy has been defined by sagittal

B. Lassale; G. Morvan; M. Gottin

1984-01-01

89

The anatomy of anatomy: a review for its modernization.  

PubMed

Anatomy has historically been a cornerstone in medical education regardless of nation or specialty. Until recently, dissection and didactic lectures were its sole pedagogy. Teaching methodology has been revolutionized with more reliance on models, imaging, simulation, and the Internet to further consolidate and enhance the learning experience. Moreover, modern medical curricula are giving less importance to anatomy education and to the acknowledged value of dissection. Universities have even abandoned dissection completely in favor of user-friendly multimedia, alternative teaching approaches, and newly defined priorities in clinical practice. Anatomy curriculum is undergoing international reformation but the current framework lacks uniformity among institutions. Optimal learning content can be categorized into the following modalities: (1) dissection/prosection, (2) interactive multimedia, (3) procedural anatomy, (4) surface and clinical anatomy, and (5) imaging. The importance of multimodal teaching, with examples suggested in this article, has been widely recognized and assessed. Nevertheless, there are still ongoing limitations in anatomy teaching. Substantial problems consist of diminished allotted dissection time and the number of qualified anatomy instructors, which will eventually deteriorate the quality of education. Alternative resources and strategies are discussed in an attempt to tackle these genuine concerns. The challenges are to reinstate more effective teaching and learning tools while maintaining the beneficial values of orthodox dissection. The UK has a reputable medical education but its quality could be improved by observing international frameworks. The heavy penalty of not concentrating on sufficient anatomy education will inevitably lead to incompetent anatomists and healthcare professionals, leaving patients to face dire repercussions. PMID:20205265

Sugand, Kapil; Abrahams, Peter; Khurana, Ashish

90

[Anatomy and anthropology].  

PubMed

Methodological aspects of anatomy and anthropology are discussed as systems of sciences in their formation. The base of these systems is the laws of materialist dialectics on the unity of the structure and function and on relation of the social to the biological as hierarchically highest form of the matter movement towards the lowest form. In this classification of the systems of anthropological and anatomical sciences a heliocentric principle is used. Tasks of the bordering sciences--anatomical anthropology are considered. Its task is to study forms and factors on anatomical changeability of the organism. PMID:7436758

Nikitiuk, B A

1980-09-01

91

NCI Statement on Mammography Screening  

Cancer.gov

A recent report in the scientific literature has reawakened debate about the value of screening mammograms. The analysis, which appeared in The Lancet on October 20, 2001, reviewed the large, long-term mammography trials upon which the NCI and other groups have based their recommendations and guidelines concerning mammography screening.

92

NCI Mouse Repository - Ordering Information  

Cancer.gov

Mouse models are provided free of charge through the NCI Mouse Repository, however, the customer is responsible for shipping charges if the shipment must go by air or special truck. There is no charge for normal truck delivery. Up to three (3) breeder pairs are routinely supplied on an order. On occasion, larger numbers of breeder pairs may be available - please inquire.

93

All NCI MERIT Award Recipients  

Cancer.gov

Updated: 09/07/2012 Updated: 09/07/2012 All NCI MERIT Award Recipients 2012 Kinzler, Kenneth W.Genes from the FAP LocusJohns Hopkins University 2011 Kohwi-Shigematsu, TerumiStudies on Gene Regulation by Chromatin OrganizationUniversity of California

94

NCI Awards Contract for Geographic Information System to Support Breast Cancer Research on Long Island  

Cancer.gov

The National Cancer Institute (NCI) announced today the award of a contract to AverStar, Inc., of Vienna, Va., to develop and implement a prototype geographic information system (GIS) for breast cancer studies as part of the Long Island Breast Cancer Study Project (LIBCSP). Questions and Answers

95

HMO Research Network Receives NCI Funding to Establish Cancer Research Network  

Cancer.gov

The National Cancer Institute (NCI) announced today that it has awarded funding to the HMO Research Network to expand and strengthen its research capabilities with a focus on cancer, and to launch initial projects studying ways to increase effective cancer prevention and control efforts among enrollees in health maintenance organizations.

96

Health Instruction Packages: Cardiac Anatomy.  

ERIC Educational Resources Information Center

|Text, illustrations, and exercises are utilized in these five learning modules to instruct nurses, students, and other health care professionals in cardiac anatomy and functions and in fundamental electrocardiographic techniques. The first module, "Cardiac Anatomy and Physiology: A Review" by Gwen Phillips, teaches the learner to draw and label…

Phillips, Gwen; And Others

97

Health Instruction Packages: Cardiac Anatomy.  

ERIC Educational Resources Information Center

Text, illustrations, and exercises are utilized in these five learning modules to instruct nurses, students, and other health care professionals in cardiac anatomy and functions and in fundamental electrocardiographic techniques. The first module, "Cardiac Anatomy and Physiology: A Review" by Gwen Phillips, teaches the learner to draw and label…

Phillips, Gwen; And Others

98

Anatomy of a Dansgaard-Oeschger warming transition: High-resolution analysis of the North Greenland Ice Core Project ice core  

NASA Astrophysics Data System (ADS)

Large and abrupt temperature oscillations during the last glacial period, known as Dansgaard-Oeschger (DO) events, are clearly observed in the Greenland ice core record. Here we present a new high-resolution chemical (2 mm) and stable isotope (20 mm) record from the North Greenland Ice Core Project (NGRIP) ice core at the onset of one of the most prominent DO events of the last glacial, DO-8, observed ˜38,000 years ago. The unique, subannual-resolution NGRIP record provides a true sequence of change during a DO warming with detailed annual layer counting of very high depth resolution geochemical measurements used to determine the exact duration of the transition. The continental ions, indicative of long-range atmospheric loading and dustiness from East Asia, are the first to change, followed by the snow accumulation, the moisture source conditions, and finally the atmospheric temperature in Greenland. The sequence of events shows that atmospheric and oceanic source and circulation changes preceded the DO warming by several years.

Thomas, Elizabeth R.; Wolff, Eric W.; Mulvaney, Robert; Johnsen, Sigfus J.; Steffensen, Jorgen P.; Arrowsmith, Carol

2009-04-01

99

NCI Cancer Bulletin for November 28, 2006  

Cancer.gov

? NCI Cancer Bulletin NCI Cancer BulletinEliminating the Suffering and Death Due to Cancer A Publication of the National Cancer Institute U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health NIH Publication No. 05-5498 http://www.cancer.gov November

100

NCI Cancer Bulletin for March 21, 2006  

Cancer.gov

? NCI Cancer Bulletin NCI Cancer BulletinEliminating the S?ffering and Death D?e to Cancer A Publication of the National Cancer Institute U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health NIH Publication No. 05-5498 http://www.cancer.gov March

101

NCI Cancer Bulletin for July 5, 2005  

Cancer.gov

1 NCI Cancer Bulletin NCI Cancer BulletinEliminating the Suffering and Death Due to Cancer A Publication of the National Cancer Institute U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health NIH Publication No. 05-5498 http://www.cancer.gov D

102

NCI Cancer Bulletin for February 21, 2006  

Cancer.gov

? NCI Cancer Bulletin NCI Cancer BulletinEliminating the Suffering and Death Due to Cancer A Publication of the National Cancer Institute U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health NIH Publication No. 05-5498 http://www.cancer.gov February

103

NCI Cancer Bulletin for August 1, 2006  

Cancer.gov

? NCI Cancer Bulletin NCI Cancer BulletinEliminating the S?ffering and Death D?e to Cancer A Publication of the National Cancer Institute U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health NIH Publication No. 05-5498 http://www.cancer.gov August

104

Incorporating 3D virtual anatomy into the medical curriculum  

Microsoft Academic Search

The introduction of the Visible Human Project by Ackerman in 1995, described in the seminal paper in 1996 [9], brought a promise to anatomists that these two frozen, milled, and digitized cadavers---the Visible Male and Female---would revolutionize anatomy teaching by providing the most complete and detailed anatomical images ever. This vision could be compared to the proverbial \\

Celina Imielinska; Pat Molholt

2005-01-01

105

NCI at Frederick: Visitor's Guide  

Cancer.gov

The NCI at Frederick is located within the Ft. Detrick U.S. Army facility in Frederick, Maryland. Please be aware that you will be asked to provide Ft. Detrick security with proof of identification, and your vehicle will be briefly searched, before being allowed to enter the facility grounds. Visitors must check in with Protective Services to receive their Visitor Badges. Below you will find some useful maps of the Campus area and driving directions for many common starting points.

106

NCI Mouse Repository - Ordering Information  

Cancer.gov

You may select to have mice recovered for you at NCI-Frederick. After their genotype and health status has been verified, live animals will be delivered to you. You will be notified when mice become available for shipping. Please expect to receive at least one mutant carrier within 16-20 weeks. There is no charge for the cryorecovery procedure. Please note that cryorecoveries may be performed in a facility that has a history of exposure to murine norovirus.

107

Anatomie de la région labiale  

Microsoft Academic Search

The phylogenetic and  embryologic basis and compared anatomy emphasize the understanding of the multiform organization, complex functions for the cosmetic aspects of the facial expression beyond an aged evolution doesn’t disturb the original smiling.

P Caix

2002-01-01

108

Olfaction: anatomy, physiology and behavior  

PubMed Central

The anatomy, physiology and function of the olfactory system are reviewed, as are the normal effects of olfactory stimulation. It is speculated that olfaction may have important but unobtrusive effects on human behavior.

Benignus, Vernon A.; Prah, James D.

1982-01-01

109

NCI at Frederick: Accessioning System Consolidation Project  

Cancer.gov

While these separate systems have been largely successful in meeting the requirements of individual service providers and customer groups, the dissimilarities among individual systems have led to an inconsistent user experience and difficulties in reporting across service areas.

110

The anatomy of the mermaid.  

PubMed

Investigation of the anatomy of the mermaid and of mermaid lore has revealed a tangled web of stories, sightings and specimens of the most diverse nature, extending worldwide into the realms of folklore and legend, zoology and cryptozoology, anatomy, physiology, radiography and folk medicine, ethnography, social history and the history of science. The stereotype we know as the mermaid is surely a fit subject for further serious study PMID:11620025

Heppell, D

111

Design and Development of a New Facility for Teaching and Research in Clinical Anatomy  

NSDL National Science Digital Library

This article discusses factors in the design, commissioning, project management, and intellectual property protection of developments within a new clinical anatomy facility. The project was aimed at creating cost-effective facilities that would address widespread concerns over anatomy teaching, and support research and community interaction. Discussed are the considerations made to develop a facility that comprises an engaging learning environment, modes to support a range of pedagogies appropriate to the needs of healthcare professionals at different stages of their careers.

2009-02-01

112

NCI Community Cancer Centers Program - Media Center Overview  

Cancer.gov

NCI Community Cancer Centers Program - Media Center Overview Search NCCCP NCCCP Home About Focus Areas NCI in the Community News & Publications Contact Contact For General Information Frank Blanchard (Contractor) Director,

113

NCI-Bethesda Animal Care and Use Committee  

Cancer.gov

The NCI Animal Care and Use Committee (NCI-ACUC) is established to oversee the institute's animal program, facilities and procedures and, to advise the Scientific Director on all matters of animal care and use at the institute.

114

NCI Community Cancer Centers Program - Participating Program Sites  

Cancer.gov

NCI Community Cancer Centers Program - Participating Program Sites Search NCCCP NCCCP Home About Focus Areas NCI in the Community News & Publications Contact About Overview For Patients and Public NCCCP Progress Reports and Tools NCCCP Hospitals

115

Recommendations Accepted to Revamp NCI Clinical Trials System  

Cancer.gov

The National Cancer Advisory Board (NCAB) of the National Cancer Institute (NCI) today accepted 22 strategic proposals for revamping the NCI's cancer clinical trials system and a five-year implementation plan to accomplish the changes.

116

Student perceptions about learning anatomy  

NASA Astrophysics Data System (ADS)

This research study was conducted to examine student perceptions about learning anatomy and to explore how these perceptions shape the learning experience. This study utilized a mixed-methods design in order to better understand how students approach learning anatomy. Two sets of data were collected at two time periods; one at the beginning and one at the end of the academic semester. Data consisted of results from a survey instrument that contained open-ended questions and a questionnaire and individual student interviews. The questionnaire scored students on a surface approach to learning (relying on rote memorization and knowing factual information) scale and a deep approach to learning (understanding concepts and deeper meaning behind the material) scale. Students were asked to volunteer from four different anatomy classes; two entry-level undergraduate courses from two different departments, an upper-level undergraduate course, and a graduate level course. Results indicate that students perceive that they will learn anatomy through memorization regardless of the level of class being taken. This is generally supported by the learning environment and thus students leave the classroom believing that anatomy is about memorizing structures and remembering anatomical terminology. When comparing this class experience to other academic classes, many students believed that anatomy was more reliant on memorization techniques for learning although many indicated that memorization is their primary learning method for most courses. Results from the questionnaire indicate that most students had decreases in both their deep approach and surface approach scores with the exception of students that had no previous anatomy experience. These students had an average increase in surface approach and so relied more on memorization and repetition for learning. The implication of these results is that the learning environment may actually amplify students' perceptions of the anatomy course at all levels and experiences of enrolled students. Instructors wanting to foster deeper approaches to learning may need to apply instructional techniques that both support deeper approaches to learning and strive to change students' perceptions away from believing that anatomy is strictly memorization and thus utilizing surface approaches to learning.

Notebaert, Andrew John

117

The place of surface anatomy in the medical literature and undergraduate anatomy textbooks.  

PubMed

The aims of this review were to examine the place of surface anatomy in the medical literature, particularly the methods and approaches used in teaching surface and living anatomy and assess commonly used anatomy textbooks in regard to their surface anatomy contents. PubMed and MEDLINE databases were searched using the following keywords "surface anatomy," "living anatomy," "teaching surface anatomy," "bony landmarks," "peer examination" and "dermatomes". The percentage of pages covering surface anatomy in each textbook was calculated as well as the number of images covering surface anatomy. Clarity, quality and adequacy of surface anatomy contents was also examined. The search identified 22 research papers addressing methods used in teaching surface anatomy, 31 papers that can help in the improvement of surface anatomy curriculum, and 12 anatomy textbooks. These teaching methods included: body painting, peer volunteer surface anatomy, use of a living anatomy model, real time ultrasound, virtual (visible) human dissector (VHD), full body digital x-ray of cadavers (Lodox(®) Statscan(®) images) combined with palpating landmarks on peers and the cadaver, as well as the use of collaborative, contextual and self-directed learning. Nineteen of these studies were published in the period from 2006 to 2013. The 31 papers covered evidence-based and clinically-applied surface anatomy. The percentage of surface anatomy in textbooks' contents ranged from 0 to 6.2 with an average of 3.4%. The number of medical illustrations on surface anatomy varied from 0 to 135. In conclusion, although there has been a progressive increase in publications addressing methods used in teaching surface anatomy over the last six to seven years, most anatomy textbooks do not provide students with adequate information about surface anatomy. Only three textbooks provided a solid explanation and foundation of understanding surface anatomy. Anat Sci Educ 6: 415-432. © 2013 American Association of Anatomists. PMID:23650274

Azer, Samy A

2013-05-06

118

NCI Funded Research Portfolio - Y01CO008115- Detail  

Cancer.gov

The National Cancer Institute (NCI) Information Services and Computer Systems (ISCS) is seeking expert support services. These services will supplement and aid our mission efforts in the achievement of its programs. The NCI has a need for a contractor to provide support for NCI activities. This will require an understanding of the NCI's mission and organization as well as knowledge of practices and all applicable security standards and guidelines.

119

NCI: SBIR & STTR - Investor Forum - Collaborators  

Cancer.gov

The 2012 NCI SBIR Investor Forum was sponsored by The National Cancer Institute's SBIR Development Center in partnership with the Foundation for the National Institutes of Health (FNIH) and in collaboration with Prescience International.

120

NCI Community Cancer Centers Program (NCCCP)  

Cancer.gov

NCI Community Cancer Centers Program (NCCCP) Pilot Program Summary January 2007 1 of 5 Cancer Care in the United States: • The pace of research in understanding cancer has accelerated in recent years, raising the need for more effective

121

NCI: Research Resources > Resources by Category  

Cancer.gov

Skip Navigation Home Resources by Category Resources by DOC Related Links Advanced Search NCI Cancer Models Database A database of mouse, rat, and other animal models of human cancers submitted by cancer... Read More Dietary Assessment Calibration/Validation

122

NCI-Frederick Laboratory Animal Medicine Home  

Cancer.gov

LABORATORY ANIMAL MEDICINE (NCI-Bethesda) Providing quality laboratory animal care and support for your research endeavors Under Construction. Check back soon.      Privacy Policy  |  Developed by C&SS |  Internet Toolkit

123

Discovery | NCI Experimental Therapeutics (NExT)  

Cancer.gov

Skip to Content Search this site DISCOVERY Overview Chemical Biology Consortium Discovery Activities in DTP Discovery Activities in CCR Other NCI Programs Last Updated: 10/28/10 Georgetown University Medical Center The chemical diversity

124

Discovery | NCI Experimental Therapeutics (NExT)  

Cancer.gov

Skip to Content Search this site DISCOVERY Overview Chemical Biology Consortium Discovery Activities in DTP Discovery Activities in CCR Other NCI Programs Last Updated: 10/28/10 North Carolina Comprehensive Chemical Biology Center Stephen

125

NCI: Research Resources > Resources by Category  

Cancer.gov

NCI recognizes that environmental tobacco smoke (ETS) is an important preventable cause of death from cancer and other illnesses and that many Americans, both adults and children, remain at significant risk from ETS exposure.

126

NCI: Research Resources > Resources by Category  

Cancer.gov

Skip Navigation Home Resources by Category Resources by DOC Related Links Advanced Search Integrative Cancer Biology Program (ICBP) Website NCI's extramural Integrative Cancer Biology Program (ICBP) focuses on the analysis of cancer as a complex biological...

127

NCI: Research Resources > Resources by Category  

Cancer.gov

Skip Navigation Home Resources by Category Resources by DOC Related Links Advanced Search The National Cancer Institute's Web Site - Cancer.gov The NCI's gateway Web site, Cancer.gov, provides access to: Cancer information, including the PDQ... Read

128

NCI: Research Resources > Resources by Category  

Cancer.gov

Skip Navigation Home Resources by Category Resources by DOC Related Links Advanced Search NCI Cancer Models Database A database of mouse, rat, and other animal models of human cancers submitted by cancer... Read More Cancer Genetics Network (CGN)

129

NCI-Frederick PHL - Courier Services  

Cancer.gov

Courier services can be arranged through Stephanie Smith (301-846-1281), Histotechnology Departmental Administrative Assistant, for the collection of animals, samples, or other materials directly from the NIH-Bethesda campus to our laboratory at NCI Frederick.

130

NCI: Research Resources > Resources by Category  

Cancer.gov

This National Cancer Institute (NCI) Web site aims to provide resources to clinicians and researchers who are developing new and improving existing models for cancer risk, validating these models and evaluating their utility in research and clinic settings.

131

NCI: Research Resources > Resources by Category  

Cancer.gov

Skip Navigation Home Resources by Category Resources by DOC Related Links Advanced Search CCR Research Directory The CCR Research Directory provides an overview of each Branch, Laboratory, and Program as well as links to individual Web... Read More NCI

132

NCI announces plans to reinvigorate clinical trials;  

Cancer.gov

The National Cancer Institute (NCI) has announced major changes to be made in the long-established Clinical Trials Cooperative Group Program that conducts many of the nationwide trials of new cancer therapies.

133

NCI Clinical Trials Training for Nurses  

Cancer.gov

The AICC NCI Clinical Trials Training for Nurses program provides nurses with the opportunity to spend fiv weeks in the United States learning the role of the research in caring for patients in clinical trials

134

NCI's Role in the Development of Endostatin  

Cancer.gov

On Sept. 13, 1999, a report in the Wall Street Journal stated incorrectly that National Cancer Institute (NCI) scientists have "failed" to replicate Judah Folkman's original findings showing that the antiangiogenesis compound endostatin can dramatically shrink tumors in mice

135

Visual Standards for NCI Social/New Media Channels  

Cancer.gov

Updated: 05/03/2012 Updated: 05/03/2012 Visual Standards for NCI Social/New Media Channels The NCI New Media Style Guide details the visual elements involved in the creation of social media sites, video/media, and applications for NCI. The elements

136

NCI Community Cancer Centers Program - Related Programs Overview  

Cancer.gov

One or more of the NCCCP’s four focus areas is shared by several NCI programs – including the NCI Cancer Centers Program, Community Clinical Oncology Program, Community Network Program, and others. The NCCCP will incorporate best practices from other NCI community cancer programs in delivering services to these communities.

137

NCI Funded Research Portfolio - Y01CO008014- Detail  

Cancer.gov

This Interagency Agreement covers base support services provided by the U.S. Army Garrison to National Cancer Institute (NCI) at Fort Detrick. Fort Detrick is an Army Medical Installation that is home to the United States Army Medical Research and Material Command (USAMRMC), the National Cancer Institute (NCI) aka NCI-Frederick and other mission partners.

138

NCI DEA - Consumer Guides for Peer Review  

Cancer.gov

The NCI Consumers' Cancer Dictionary for Peer Review is deigned to provide concise definitions of technical terms frequently used in applications for NCI-sponsored investigator-initiated research. The terms include those commonly associated with the molecular biology of cancer, immunology, and clinical oncology. These definitions, in association with the review process, will increase your familiarity and understanding of the biology and clinical aspects of cancer. We hope this will facilitate and make your participation in the Peer Review process more meaningful.

139

Discovery | NCI Experimental Therapeutics (NExT)  

Cancer.gov

The NCI Chemical Biology Consortium (CBC) was recently established to facilitate the discovery and development of new agents to treat cancer. The Consortium brings together chemical biologists and molecular oncologists from government, industry, and academia to address unmet needs in therapeutic oncology. Through the CBC and the interactions among the various Participants, the NCI's drug discovery and development pipeline can be active from target identification through proof-of-concept clinical trials.

140

Reaction of 1\\Ncy,2\\Ncy,3\\Ncy,4\\Ncy-pyrido[4,3-d]pyrimidinium bromide derivatives with molecular iodine: Comparative structure and spectroscopic analysis  

NASA Astrophysics Data System (ADS)

New salts C27H22N3O2BrI2 (1) and C27H19N3O2Br4I2·2CHCl3·2H2O (2) were synthesized by the iodination of derivatives of 1,3-dimethyl-2,4-dioxo-5,6,7-R-1\\Ncy,2\\Ncy,3\\Ncy,4\\Ncy-pyrido[4,3-d]pyrimidinium bromide (R = phenyl (1a), p-bromphenyl (2a)) with an equimolar amount of iodine. The positive values of enthalpy (?H) and entropy (?S) indicate that the complexation of organic bromide and iodine molecule in chloroform solution is mainly entropically driven. The molecular and crystal structures (1) and (2) are studied by X-ray diffraction analysis. The structure of diiodinebromide 1 is composed of separate almost liner BrI2- and 1,3-dimethyl-2,4-dioxo-5,6,7-thriphenyl-1\\Ncy,2\\Ncy,3\\Ncy,4\\Ncy-pyrido[4,3-d]pyrimidinium cation. The crystal structure 2 is built up of alternate layers of (CHNOBr3+)(I3-) (A) and (Br2I-)(\\ScyH\\Scyl3) (B), connected to each other by hydrogen bonds Br(BrI)\\ctdot H(CHNOBr3+). The formation of the ions I3- and Br2I- occurs via the disproportionation of I2Br- under the action of solvent on C27H19N3O2Br4I2·2CHCl3·2H2O (2) crystallization.

Chernov'yants, Margarita S.; Burykin, Igor V.; Kostrub, Vladimir V.; Tsupak, Evgeny B.; Starikova, Zoya A.; Kirsanova, Julia A.

2012-02-01

141

[Magnetic resonance imaging elbow anatomy].  

PubMed

Knowledge of the anatomy of the elbow joint has become intricate due to the advent of magnetic resonance imaging (MRI) techniques, as they are superior to represent the different soft tissues. This advantage allows evaluating in detail the increasingly frequent pathologic processes that occur in high performance athletes. The ideal MRI technique includes having the patient in a comfortable position, using an appropriate surface antenna and the right sequences in the appropriate planes depending on the entity. Being familiar with the normal elbow anatomy is crucial to properly identify the pathology and avoid potential diagnostic errors. PMID:22509650

Rodríguez-Ramírez, C L; Aguila-Mendoza, A

142

The NCI Thesaurus quality assurance life cycle.  

PubMed

The National Cancer Institute Enterprise Vocabulary Services (NCI EVS) uses a wide range of quality assurance (QA) techniques to maintain and extend NCI Thesaurus (NCIt). NCIt is a reference terminology and biomedical ontology used in a growing number of NCI and other systems that extend from translational and basic research through clinical care to public information and administrative activities. Both automated and manual QA techniques are employed throughout the editing and publication cycle, which includes inserting and editing NCIt in NCI Metathesaurus. NCI EVS conducts its own additional periodic and ongoing content QA. External reviews, and extensive evaluation by and interaction with EVS partners and other users, have also played an important part in the QA process. There have always been tensions and compromises between meeting the needs of dependent systems and providing consistent and well-structured content; external QA and feedback have been important in identifying and addressing such issues. Currently, NCI EVS is exploring new approaches to broaden external participation in the terminology development and QA process. PMID:19475726

de Coronado, Sherri; Wright, Lawrence W; Fragoso, Gilberto; Haber, Margaret W; Hahn-Dantona, Elizabeth A; Hartel, Francis W; Quan, Sharon L; Safran, Tracy; Thomas, Nicole; Whiteman, Lori

2009-06-01

143

Integrating partonomic hierarchies in anatomy ontologies  

PubMed Central

Background Anatomy ontologies play an increasingly important role in developing integrated bioinformatics applications. One of the primary relationships between anatomical tissues represented in such ontologies is part-of. As there are a number of ways to divide up the anatomical structure of an organism, each may be represented by more than one valid partonomic (part-of) hierarchy. This raises the issue of how to represent and integrate multiple such hierarchies. Results In this paper we describe a solution that is based on our work on an anatomy ontology for mouse embryo development, which is part of the Edinburgh Mouse Atlas Project (EMAP). The paper describes the basic conceptual aspects of our approach and discusses strengths and limitations of the proposed solution. A prototype was implemented in Prolog for evaluation purposes. Conclusion With the proposed name set approach, rather than having to standardise hierarchies, it is sufficient to agree on a suitable set of basic tissue terms and their meaning in order to facilitate the integration of multiple partonomic hierarchies.

Burger, Albert; Davidson, Duncan; Yang, Yiya; Baldock, Richard

2004-01-01

144

Osseous Anatomy of the Orbital Apex  

Microsoft Academic Search

The osseous anatomy of the orbital apex may be difficult to conceptualize because of the dif- ferent shapes and orientations of the optic ca- nal, superior and inferior orbital fissures, and foramen rotundum. However, knowing this anatomy is crucial to evaluate complex frac- tures, tumors, and inflammatory processes in- volving the orbital apex. Evaluating osseous anatomy of the orbital apex

David L. Daniels; Leighton P. Mark; Mahmood F. Mafee; Bruce Massaro; Lloyd E. Hendrix; Katherine A. Shaffer; David Morrissey; Charles W. Horner

145

Anatomy of a school  

Microsoft Academic Search

Ohio's Martin W. Essex School for the Gifted has served over 400 gifted secondary students over the past seven years. High school students from throughout Ohio spend one week on the Ohio State University campus for academic, cultural and social activities. The project serves as a model for providing differential experiences for gifted secondary students under the auspices of a

Joan S. Wolf; Raymond H. Swassing; George R. Fichter

1984-01-01

146

An atlas of radiological anatomy  

Microsoft Academic Search

This book contains a wealth of radiologic images of normal human anatomy; plain radiographs, contrast-enhanced radiographs, and computed tomography (CT) scans. There are 18 pages of magnetic resonance (MR) images, most on the brain and spinal cord, so that there are only two pages on MR imaging of the heart and two pages on abdominal and pelvic MR imaging. Twelve

J. Weir; P. Abrahams

1986-01-01

147

How Much Anatomy is Enough?  

NSDL National Science Digital Library

This article describes a study conducted at 8 Dutch Medical Schools investigating the effect of various didactic approaches to teaching anatomy on performance. Outcomes discussed include that good test performance is not related to teaching style, but rather course hours, clinical relevance, and revisiting anatomical concepts.

2008-08-01

148

The Anatomy of Health Insurance  

Microsoft Academic Search

This article describes the anatomy of health insurance. It begins by considering the optimal design of health insurance policies. Such policies must make tradeoffs appropriately between risk sharing on the one hand and agency problems such as moral hazard (the incentive of people to seek more care when they are insured) and supplier-induced demand (the incentive of physicians to provide

David M. Cutler; Richard J. Zeckhauser

1999-01-01

149

Head and neck vascular anatomy.  

PubMed

Conventional computed tomography (CT) and magnetic resonance (MR) angiography provide excellent vascular images; however, every radiologist interpreting routine cross-sectional imaging of the head and neck must recognize normal and abnormal vascular structures. Knowledge of the normal cross-sectional appearance of vessels can help to define spacial anatomy and provide for recognition of abnormal vessels. Intracranially, the major arterial branches of the Circle of Willis are routinely visualized on MR and CT, as are the dural venous sinuses and major tributaries to the deep and superficial venous system. Using a combination of CT and MR images, we demonstrate the normal cross-sectional vascular anatomy of the head and neck and the important anatomic relationships key to accurate imaging analysis. PMID:9449756

Johnson, M H

1998-02-01

150

Hip: Anatomy and US technique  

PubMed Central

Ultrasound (US) has always had a relatively limited role in the evaluation of the hip due to the deep location of this joint. However, many hip diseases are well detectable at US, but before approaching such a study it is necessary to be thoroughly familiar with the normal anatomy and related US images. The study technique is particularly important as optimization of various parameters is required, such as probe frequency, focalization, positioning of the probe, etc. Also the patient’s position is important, as it varies according to the area requiring examination. For the study of the anterior structures, the patient should be in the supine position; for the medial structures, the leg should be abducted and rotated outward with the knee flexed; for the lateral structures, the patient should be in the controlateral decubitus position; for the posterior structures the patient must be in the prone position. US study of the hip includes assessment of the soft tissues, tendons, ligaments and muscles, and also of the bone structures, joint space and serous bursae. The purpose of this article is to review the normal anatomy of the hip as well as the US anatomy of this joint.

Molini, L.; Precerutti, M.; Gervasio, A.; Draghi, F.; Bianchi, S.

2011-01-01

151

Anatomy of the infant head  

SciTech Connect

This text is mainly an atlas of illustration representing the dissection of the head and upper neck of the infant. It was prepared by the author over a 20-year period. The commentary compares the anatomy of the near-term infant with that of a younger fetus, child, and adult. As the author indicates, the dearth of anatomic information about postnatal anatomic changes represents a considerable handicap to those imaging infants. In part 1 of the book, anatomy is related to physiologic performance involving the pharynx, larynx, and mouth. Sequential topics involve the regional anatomy of the head (excluding the brain), the skeleton of the cranium, the nose, orbit, mouth, larynx, pharynx, and ear. To facilitate use of this text as a reference, the illustrations and text on individual organs are considered separately (i.e., the nose, the orbit, the eye, the mouth, the larynx, the pharynx, and the ear). Each part concerned with a separate organ includes materials from the regional illustrations contained in part 2 and from the skeleton, which is treated in part 3. Also included in a summary of the embryologic and fetal development of the organ.

Bosma, J.F.

1986-01-01

152

NCI Computer Services — CBIIT: Welcome to the NCI Center for Biomedical Informatics and Information Technology  

Cancer.gov

NCS manages the IT infrastructure for the NCI enterprise. This includes the hardware, hardware-maintenance contracts, software, network, labor, structures, and IT policies required to support the scientific and administrative activities of the Institute.

153

Exploration of the facial nerve canal by high-resolution computed tomography: Anatomy and pathology  

Microsoft Academic Search

A correlative study of the anatomy and the radiological appearance of the intratemporal course of the facial nerve canal was carried out. Isolated temporal bones and temporal bones of cadaver heads were examined with thin-section high-resolution computed tomography in the axial, coronal and Stenvers' projections, then sectioned with a microtome and the radiologic and anatomic images were correlated. Appropriate projections

A. Valavanis; S. Kubik; M. Oguz

1983-01-01

154

Body-Painting: A Tool Which Can Be Used to Teach Surface Anatomy  

PubMed Central

Introduction The primary method of learning the surface anatomy is by making the students mark structures on mummified bodies. The students feel that learning the surface anatomy on mummified cadavers is not interesting. The present project on learning the surface anatomy through the body painting method was undertaken to evoke interest among the students. Materials and Methods Physiotherapy and dental undergraduate students who volunteered were involved in this study. A few surface anatomy classes were conducted by using the traditional method and a few more by using the body painting exercise. Non toxic body paints of various colours and brushes of different sizes were used for the body painting. Results A feedback was obtained from the students by using a structured questionnaire. The students opined that the body painting method was advantageous to them in learning the human anatomy. They also felt that they could have more practice sessions in any setting other than in the classroom and that they did not need to rely upon the mummified bodies. They described the body painting method as self explanatory, which gave them the feel of live structures. Conclusion This project was successful in achieving its objectives as the students felt that the method was exciting, with lots of fun during the learning. The body painting method was well accepted by the students as an effective method for learning the surface and the clinical anatomy.

Nanjundaiah, Komala; Chowdapurkar, Sheshgiri

2012-01-01

155

NCI/CPFP - 2010 Application Catalog - Program Description - Ireland-Northern Ireland-NCI Cancer Consortium  

Cancer.gov

The NCI has formed a multilateral partnership with Ireland and Northern Ireland to promote cooperation in all aspects of cancer research, treatment, and prevention. As part of this Ireland—Northern Ireland—NCI Cancer Consortium, the CPFP is open to applicants from Ireland and Northern Ireland. It is intended that individuals applying through the Consortium will pursue careers in cancer prevention in Ireland or Northern Ireland upon completion of the fellowship.

156

NCI Funded Research Portfolio - ZIBBC010906 Detail  

Cancer.gov

On the basis of the results of preclinical studies in animal models, and following obtaining support from the Director NCI, Dr. Waldmann oversaw an interinstitute collaboration (NCI-NIAID) directed toward the production under current good manufacturing practices (cGMP) of rhIL-15 for clinical trials in patients with metastatic malignancy and those with HIV AIDS. In a modification of an expression system and purification method developed in the Waldmann Laboratory, the Biopharmaceutical Development Program (BDP) of the National Cancer Institute produced recombinant human IL-15 (rhIL-15).

157

Endoscopic Anatomy of the Middle Ear  

Microsoft Academic Search

Good knowledge of anatomy is fundamental for every surgeon. Middle ear anatomy is really complex and sometimes is challenging\\u000a for otologists, who need to explore every single compartment for a radical removal of pathology. With introduction of the\\u000a endoscope in middle ear surgery, anatomy of middle ear spaces has become wider and clearer due to a better magnification and\\u000a to

Daniele Marchioni; Gabriele Molteni; Livio Presutti

2011-01-01

158

NCI Contacts for Grantees Affected by Hurricane Katrina  

Cancer.gov

NCI is very aware of and responsive to the needs of our grantees who are located in the hurricane-affected region. We recognize the likelihood of damage and loss to research infrastructure and research resources due to the storm and flooding. As such, NCI is committed to working with affected researchers and their institutions to ensure that their research efforts can continue. We stand ready to provide them special assistance and address concerns about their NCI-sponsored research efforts.

159

NCI Community Cancer Centers Program - Media Center Overview  

Cancer.gov

NCI Community Cancer Centers Program - Media Center Overview Search NCCCP For General Information Frank Blanchard (Contractor) Director, Public Affairs SAIC-Frederick, Inc. National Cancer Institute at Frederick

160

NCI Community Cancer Centers Program - Pilot Subcommittees - Advocacy  

Cancer.gov

NCI Community Cancer Centers Program - Pilot Subcommittees - Advocacy Search NCCCP Pilot Goals Overview Pilot Subcommittees Pilot Executive Subcommittee Disparities Clinical Trials Information Technology Biospecimens

161

[Anatomy of the eustachian tube].  

PubMed

The auditory tube is part of a complex anatomical functional system, which even today is not completely explained. It plays a crucial role in the understanding of the pathogenesis of chronic middle ear infections and possible therapeutic interventions--particularly in infants. This paper summarizes the current knowledge of eustachian tube gross anatomy and histology, its peritubular structures and its topographic relationship to the internal carotid artery in adults. Anatomical aspects specific to infancy are related to their possible influence on tube function. PMID:23670679

Böckers, A

2013-06-01

162

NCI at Frederick: Discovery Cafe Catering  

Cancer.gov

When the new Discovery Café opened in March of 2011, the much-improved eatery represented months of planning, design, and construction to completely renovate the former cafeteria. With new furniture, lighting, carpeting, and colorful wall coverings, the Discovery Café provided a comfortable and aesthetically pleasing place for NCI at Frederick staff to relax and eat.

163

Usual Dietary Intakes: The NCI Method  

Cancer.gov

The premise of the NCI method is that usual intake is equal to the probability of consumption on a given day times the average amount consumed on a "consumption day." The exact methods used for dietary components that are consumed nearly every day by nearly everyone differ slightly from those used for dietary components that are episodically consumed.

164

NCI: Research Resources > Resources by Category  

Cancer.gov

The NCI Tissue Expediter provides information on sources of human tissue specimens for cancer research and helps researchers locate the tissue and related data they need. The Tissue Expediter is a scientist with contacts in the resources community who can rapidly relate investigator needs to appropriate resources.

165

All-Ireland NCI Cancer Consortium  

Cancer.gov

AICC brings together the governments of the United States and both parts of Ireland to reduce the incidence and mortality of cancer among the Irish people, who have one of the highest rates of cancer in the Western world. AICC is administered by NCI’s Center for Global Health

166

NCI Training and Career Development Inventory  

Cancer.gov

Office of the Director, NCI DCP CCR DCEG DCCPS DEA DCTD DCB OD OD 2. Organ Systems Branch (SPORES) 3. Cancer Training Branch (CTB) 4. Comprehensive Minority Biomedical Branch (CMBB) 6. Office of Training and Education 5. Office of Preventive Oncology 7. Office of Education 1.

167

NCI at Frederick: Spotlight: Kids Day  

Cancer.gov

July 17th is the date for the NCI at Frederick and Fort Detrick Take Your Child to Work Day. This annual event allows your children to get a glimpse of some of the important work you do every day to support our mission. Registration for children is open from June 17 until July 3.

168

The Human Anatomy Teacher-Scholar: Meeting the Expectations of Educational Outcomes Research, Course Content Innovation, and Textbook Innovation for Educational Scholarship  

ERIC Educational Resources Information Center

|A human anatomy teacher-scholar is a scholar whose area of expertise includes content knowledge of the anatomical sciences (gross anatomy, histology, embryology, and/or neuroanatomy) and whose research interests and focus are centered in medical educational outcomes. The projects described in this dissertation represent endeavors I engaged in to…

Eckel, Christine Marie

2009-01-01

169

NCI Funded Research Portfolio - Z01 BC 010684 Detail  

Cancer.gov

Residents contribute to the clinical research program of the NCI and the NIH. Through their efforts as anatomic pathology residents in training, they help illuminate the pathological changes associated with cancer therapy, and explore new techniques to improve cancer diagnosis. They are critical to the patient care activities of the NCI and the NIH, and contribute to the correct diagnosis and management of disease.

170

Other Resources at NCI/NIH - SEER Pediatric Monograph  

Cancer.gov

XV 171 National Cancer Institute SEER Pediatric Monograph OTHER RESOURCES AVAILABLE AT NCI/NIH Cancer Information Service (CIS) – 1-800-4-CANCER or http://cis.nci.nih.gov/contact/faqform.html ? The Cancer Information Service is the National Cancer Institute’s

171

Cavitation corrosion of nodular cast iron (NCI) in seawater  

Microsoft Academic Search

An investigation was carried out to determine the effect of the microstructure of nodular cast iron (NCI) on its cavitation corrosion behavior in natural seawater. The cavitation tests were conducted using a cavitation-induced facility at a frequency of 20 kHz on detached specimens. Morphological examinations on cavitated specimens indicated that the surface of NCI became very rough with large size

A Al-Hashem; A Abdullah; W Riad

2001-01-01

172

NCI Cancer Bulletin for June 26, 2007 (PDF)  

Cancer.gov

? NCI Cancer Bulletin NCI Cancer Bulletin A Publication of the National Cancer Institute U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health NIH Publication No. 05-5498 http://www.cancer.gov June 26, 2007 Volume 4 | Number

173

NCI-Frederick PHL - Scheduling  

Cancer.gov

Services Price List Courier Services & Shipment Procedures Scheduling Contact Information Related Links Establishing an Account PHL Forms PHL Portal Scheduling Project scheduling will depend on the type, scope and size of the project. Detailed information

174

Functional anatomy of the internal gills of the tadpole of Litoria ewingii (Anura, Hylidae)  

Microsoft Academic Search

(1) Scanning electron microscopy and vascular casting were used to study the morphology and vascular anatomy of the fully developed internal gills of Litoria ewingii tadpoles. — (2) The four pairs of gills were located in two branchial baskets on either side of the heart. Each gill consisted of a branchial arch with gill tufts projecting ventrally and gill filters

Rosemary McIndoe; David G. Smith

1984-01-01

175

NCI: Research Resources > Resources by Category  

Cancer.gov

The Developmental Therapeutics Program of NCI operates an anti-cancer screening program for the benefit of the extramural research community. The program, which is operated at no cost to suppliers, accepts both natural and synthetic compounds from scientists in the academic and industrial communities worldwide. Entrance into this program is through a supplier-driven on-line submission form. For screening of natural product extracts, the Natural Products Branch should be contacted.

176

Visual Standards for NCI Mobile Websites & Apps  

Cancer.gov

As with desktop websites, a cohesive and recognizable identity is a valuable asset for mobile websites and apps. It also helps connect the mobile websites and apps with the organization’s digital channels so that users have a more unified user experience. This section outlines the visual standards for NCI mobile websites and apps. It does not provide guidance on how to create sites or apps (for that, see Howto.gov for more information).

177

NCI Funded Research Portfolio - ZIESC000853 Detail  

Cancer.gov

The Translational Surgical Pathology section provides diagnostic services to support the NCI, the NIH Clinical Center, other NIH Institutes, and the Urologic Oncology Branch, CCR. Many specimens are processed and studied every year. This human tissue material is used in a variety of applied research studies in collaboration with associated clinicians and under Institutional Review Board-approved protocols. We train 9 residents in anatomic pathology as well as many visiting fellows, medical students from other institutions, and CRTA fellows.

178

NCI: SBIR & STTR - News & Events - Upcoming Events  

Cancer.gov

In the session, NCI SBIR Development Center leaders will discuss new and existing initiatives to help small businesses further commercialize their innovations, including funding opportunities such as the SBIR Phase I, Phase II, and Phase II Bridge Award, and the recently launched Regulatory Assistance Program pilot program. Additionally, an SBIR grantee will share how he strategically leveraged the SBIR Program to help raise additional investor funding and advance his company's cancer technology to the next stage of development.

179

NCI Funded Research Portfolio - ZIABC011019 Detail  

Cancer.gov

Eighteen paraffin-embedded tissue blocks obtained from autopsy specimens have been collected from patients treated at NCI and outside institutions. These are currently undergoing pathology confirmation and review. A representative area of tumor will be collected from the block. DNA will be extracted from the core with standard procedures. Tumor DNA will be processed for high resolution comparative genomic hybridization. Regions of copy number change will be identified using circular binary segmentation of the array data.

180

Development | NCI Experimental Therapeutics (NExT)  

Cancer.gov

The NCI established the Developmental Therapeutics Section (DTS) within the CCR so that DCTD could use Phase 0 clinical trial designs as permitted by the FDA's Exploratory IND Guidance to evaluate agents early in the clinical development process. DTS also designs and conducts Phase I and II trials of novel agents; many of the trials are multicenter collaborations with other specialist cancer centers, oncology groups, and consortia.

181

NCI: Research Resources > Resources by Category  

Cancer.gov

The California Health Interview Survey (CHIS) provides population-based, standardized health-related data from more than 50,000 Californians selected from all 58 counties. CHIS is fielded annually (biennially before 2011) by the UCLA Center for Health Policy Research in collaboration with the California Department of Public Health and the California Department of Health Care Services. NCI supports cancer control items on CHIS.

182

Anatomy and Function of the Normal Lung  

MedlinePLUS

... Patients | | More Anatomy and Function of the Normal Lung For Patients What Kind of Medications Are There ... Need Oxygen Therapy? Other Medications To understand your lung condition, you should be familiar with how the ...

183

New Project Launched to Study Minority Populations  

Cancer.gov

The National Cancer Institute (NCI) announced today that it is accepting applications for projects that create and implement cancer control and prevention programs in minority and underserved communities to address the disparities in cancer rates within certain subgroups of the United States population.

184

Extremity Soft Tissue Sarcoma Care in the Elderly: Insights into the Generalizability of NCI Cancer Trials  

Microsoft Academic Search

Background  The projected increase in older persons in the United States, their underrepresentation in clinical trials, and the rarity\\u000a of extremity soft tissue sarcomas (ESTS) limit our understanding of ESTS care in the elderly. We explored the extent of older\\u000a age (?65 years) on patterns of ESTS care in NCI-sponsored population-based dataset.\\u000a \\u000a \\u000a \\u000a \\u000a Materials and Methods  Using the 1991–2006 Surveillance Epidemiology and End Results

Waddah B. Al-Refaie; Elizabeth B. Habermann; Vikas Dudeja; Selwyn M. Vickers; Todd M. Tuttle; Eric H. Jensen; Beth A. Virnig

2010-01-01

185

Michelangelo: Art, anatomy, and the kidney  

Microsoft Academic Search

Michelangelo: Art, anatomy, and the kidney. Michelangelo (1475–1564) had a life-long interest in anatomy that began with his participation in public dissections in his early teens, when he joined the court of Lorenzo de' Medici and was exposed to its physician-philosopher members. By the age of 18, he began to perform his own dissections. His early anatomic interests were revived

Garabed Eknoyan

2000-01-01

186

Anatomy: Simple and Effective Privacy Preservation  

Microsoft Academic Search

This paper presents a novel technique, anatomy, for publishing sen- sitive data. Anatomy releases all the quasi-identifier and s ensitive values directly in two separate tables. Combined with a grouping mechanism, this approach protects privacy, and captures a large amount of correlation in the microdata. We develop a linear-time algorithm for computing anatomized tables that obey the l-diversity privacy requirement,

Xiaokui Xiao; Yufei Tao

2006-01-01

187

Fibularis tertius: revisiting the anatomy.  

PubMed

Fibularis tertius (FT) may be used during reconstructive surgery and muscle transposition with retention of function. The muscle was examined in both lower limbs of 41 cadavers. Measurements were made of muscle belly length and width, tendon length and width, and the size of the origin on the fibula. Tendon insertion, nerve and blood supplies were also examined. FT was absent in five (6.1%) lower limbs of three (7.3%) subjects. The size of its origin demonstrated inter- and intra-individual variation. FT arose from the distal fibula and on average occupied (28.4 +/- 9.1)% (mean +/- S. D.) of the total shaft length. In all cases the tendon inserted into the dorsal surface of the shafts of both the fourth and fifth metatarsals. A small nerve branch consistently arose from the deep fibular nerve near the origin of extensor digitorum longus. The nerve ran parallel to the length of this muscle, between it and extensor hallucis longus, before piercing FT. Anatomy textbooks describe FT as inserting into the fifth metatarsal only. This study, supported by data from previous reports, suggests that the "textbook" accounts of FT should be updated to record that most commonly its tendon reaches both the fourth and fifth metatarsals. PMID:17584875

Rourke, K; Dafydd, H; Parkin, I G

2007-11-01

188

Anatomy of the avian cecum.  

PubMed

The gross anatomy of the avian ceca is reviewed. In most birds, right and left ceca arise laterally or ventrolaterally at the junction of the small and large intestines. In a few species, the ceca open into the rectum ventrally or dorsally. In many herons and bitterns, only one cecum is present, and in the secretary bird there are two pairs of ceca. Ceca are absent in woodpeckers, hummingbirds, swifts, kingfishers, pigeons, mousebirds, cuckoos, and parrots. Ceca may be classified according to length into long, moderately or poorly developed, and vestigial types. In most birds, the ceca are simple tubular structures with minor variations in shape. However, in a few species, including the ostrich, rheas, kiwis, some tinamous, the red-throated loon, screamers, the satyr tragopan, the great bustard, and the pin-tailed sandgrouse, the ceca are sacculated or have diverticula. There is usually no correlation between the development of the ceca and systematic position. Except in grouse (Tetraonidae), in which the long ceca are related to the fibre content of the diet, the correlation between cecal development and diet is extremely limited. There is no relationship between the size of the ceca and the length and width of the rectum. PMID:2575123

McLelland, J

1989-01-01

189

NCI Announces Appointment of 15 Members to its Consumer Liaison Group  

Cancer.gov

Twelve consumer advocates have taken seats as new members on the National Cancer Institute (NCI) Director's Consumer Liaison Group (DCLG), joining three returning members, as the NCI increases its initiatives to reach out to the cancer community.

190

68 FR 57471 - Submission for OMB Review; Comment Request; NCI Cancer Information Service Demographic/Customer...  

Federal Register 2010, 2011, 2012, 2013

...for OMB Review; Comment Request; NCI Cancer Information Service Demographic/Customer...Paperwork Reduction Act of 1995, the National Cancer Institute (NCI), the National Institutes...Proposed Collection: Title: The National Cancer Institute Cancer Information Service...

2003-10-03

191

NCI Cancer Bulletin for January 23, 2007 (PDF)  

Cancer.gov

Eliminating the Suffering and Death Due to Cancer During his visit to the NIH campus on January 17, President George Bush discussed cancer pre-vention with (left to right) HHS Secretary Michael Leavitt, NCI Director Dr. John E.

192

NCI and FDA Announce Joint Program to Steamline Cancer ...  

Center for Biologics Evaluation and Research (CBER)

Text Version... NCI believes that the timely and considered application of science across the continuum of discovery, development and delivery, will optimize and ... More results from www.fda.gov/downloads/advisorycommittees/committeesmeetingmaterials

193

NCI/CPFP - 2010 Application Catalog - Guidelines for Application  

Cancer.gov

Skip navigation. Table of Contents Director's Message Staff Profiles Program Description Program Information Guidelines for Application Preceptorships Bibliography Post-Fellowship Employment Life Outside the NCI Previous Page | Next Page Application

194

NCI/CPFP - 2010 Application Catalog - Program Description  

Cancer.gov

Skip navigation. Table of Contents Director's Message Staff Profiles Program Description Program Information Guidelines for Application Preceptorships Bibliography Post-Fellowship Employment Life Outside the NCI Previous Page | Next Page Application

195

NCI-Frederick Animal Holding and Technical Support Home  

Cancer.gov

Animal Holding and Technical Support - Frederick Campus Animal Holding and Technical Support Program Provides the highest quality of animal care and animal support services for all animal research at the NCI-Frederick Ensures that an investigator's

196

NCI Awards First Funding for Consortium of Cohorts Initiative  

Cancer.gov

The National Cancer Institute (NCI) today announced the funding of a new initiative to pool data and biospecimens from 10 large study populations to conduct research on gene and environment interactions.

197

Evaluability Assessment of the NCI Community Hospital Oncology Program.  

National Technical Information Service (NTIS)

The evaluability assessment of the Community Hospital Oncology Program is a demonstration program operated by the National Cancer Institute. The Community Hospital Oncology Program (CHOP) is one mechanism by which NCI implements its cancer program that bu...

K. Bowing M. Brown K. Johnson C. Schulz

1982-01-01

198

NCI Expands Office of Cancer Survivorship Web Site  

Cancer.gov

Underscoring its commitment to the growing population of cancer survivors, the National Cancer Institute (NCI) today unveiled the Office of Cancer Survivorship's (OCS) newly designed, easy-to-navigate Web site.

199

NCI Awards First Grants for the Director's Challenge  

Cancer.gov

The National Cancer Institute (NCI) announced today that it has awarded the first 10 grants of a major new initiative to define the patterns of molecular changes in tumors called "The Director's Challenge: Toward a Molecular Classification of Tumors."

200

NCI Awards First Contracts for Unconventional Innovations Program  

Cancer.gov

The National Cancer Institute (NCI) announced today that it has awarded the first five contracts of an innovative new program to develop novel, "one-stop" technologies capable of both detecting and destroying tumor cells.

201

Greek anatomist herophilus: the father of anatomy.  

PubMed

One of the most stirring controversies in the history of Anatomy is that Herophilus, an ancient Greek anatomist and his younger contemporary, Erasistratus, were accused of performing vivisections of living humans. However, this does not detract from the fact that Herophilus has made phenomenal anatomical observations of the human body which have contributed significantly towards the understanding of the brain, eye, liver, reproductive organs and nervous system. It is notable that he was the first person to perform systematic dissection of the human body and is widely acknowledged as the Father of Anatomy. He has been hailed as one of the greatest anatomists that ever lived, rivaled only by Andreas Vesalius who is regarded as the founder of modern human anatomy. PMID:21267401

Bay, Noel Si-Yang; Bay, Boon-Huat

2010-12-31

202

Greek anatomist herophilus: the father of anatomy  

PubMed Central

One of the most stirring controversies in the history of Anatomy is that Herophilus, an ancient Greek anatomist and his younger contemporary, Erasistratus, were accused of performing vivisections of living humans. However, this does not detract from the fact that Herophilus has made phenomenal anatomical observations of the human body which have contributed significantly towards the understanding of the brain, eye, liver, reproductive organs and nervous system. It is notable that he was the first person to perform systematic dissection of the human body and is widely acknowledged as the Father of Anatomy. He has been hailed as one of the greatest anatomists that ever lived, rivaled only by Andreas Vesalius who is regarded as the founder of modern human anatomy.

Bay, Noel Si-Yang

2010-01-01

203

Validation of a new radiographic protocol for Asian elephant feet and description of their radiographic anatomy.  

PubMed

Foot problems are extremely common in elephants and radiography is the only imaging method available but the radiographic anatomy has not been described in detail. The aims of this study were to develop a radiographic protocol for elephant feet using digital radiography, and to describe the normal radiographic anatomy of the Asian elephant front and hind foot. A total of fifteen cadaver foot specimens from captive Asian elephants were radiographed using a range of projections and exposures to determine the best radiographic technique. This was subsequently tested in live elephants in a free-contact setting. The normal radiographic anatomy of the Asian elephant front and hind foot was described with the use of three-dimensional models based on CT reconstructions. The projection angles that were found to be most useful were 65-70° for the front limb and 55-60° in the hind limb. The beam was centred 10-15 cm proximal to the cuticle in the front and 10-15 cm dorsal to the plantar edge of the sole in the hind foot depending on the size of the foot. The protocol developed can be used for larger-scale diagnostic investigations of captive elephant foot disorders, while the normal radiographic anatomy described can improve the diagnostic reliability of elephant feet radiography. PMID:24048633

Mumby, C; Bouts, T; Sambrook, L; Danika, S; Rees, E; Parry, A; Rendle, M; Masters, N; Weller, R

2013-09-18

204

Extramural NCI Data Access Committee: Charter  

Cancer.gov

The Extramural National Cancer Institute (NCI) Data Access Committee (DAC) will review and approve or disapprove all requests from the research community for access to controlled data of genome-wide association studies (GWAS) of cancer and other genotype-phenotype studies (including sequencing and molecular diagnostic assays) for which it is responsible. The Committee evaluates if the request conforms to NIH policies and procedures including consistency of the proposed research use with data use limitations stipulated by the submitting institution for each study.

205

The Anatomy Competence Score - A New Marker for Anatomical Ability  

NSDL National Science Digital Library

This articles describes the development of the Anatomy Competence Score (ACS), which incorporates the three domains of anatomy teaching and assessment namely: theoretical knowledge, practical 3D application of the knowledge, and clinical or bedside application of knowledge on patients.

2011-11-29

206

How To Apply | NCI Experimental Therapeutics (NExT)  

Cancer.gov

The NCI Experimental Therapeutics (NExT) pipeline is designed to assist translation to the clinic of novel therapeutic interventions, either synthetic, natural product, or biologic, arising from academic, private, or government entities. NExT is not a grant mechanism. Approved proposals gain access to drug discovery and development resources through the NExT Program. A panel of experts will review the applications based on criteria including scientific merit, feasibility, alignment with NCI mission, novelty, and clinical need.

207

How To Apply | NCI Experimental Therapeutics (NExT)  

Cancer.gov

Please note that a NExT proposal is NOT a grant application. Rather, a NExT proposal is an application to gain access to scientific capabilities and resources available to the NCI with the goal of moving promising anti-cancer concepts and novel agents into clinical testing. Applications to the NExT Program are evaluated for scientific merit, feasibility, novelty, clinical need, and alignment with NCI mission.

208

Gestalt theory and morbid anatomy.  

PubMed

Contact with medical students as a university teacher has shown that there are different types of aptitude: 5/9 of German medical students possess a visual faculty, 3/9 are kinaesthetic and only about 1/9 have the gift of the auditive faculty. Apart from this, there is a general quality which may be termed gestalt perception or gestalt blindness. The fact that for decades the attempt was made to relate qualitative differences in the characteristics of medical observations and pathological and anatomical findings to quantitative changes was the reason for the development of the concept of Relationspathologie . Intellectual pre-occupation with the perception of "gestalt qualities" has resulted in pathology in general being seen as the expression of the biophysics of open systems and making an organismic evaluation of its phenomena. The aim of all natural science is the recognition of order. Theoretical biology seeks an order free from hypotheses. Theoretical pathology involves the application of gestalt philosophy to the detection and evaluation of all potentially dangerous disturbances. Theoretical pathology has nothing to do with "natural philosophy", the "natural history viewpoint", the " vitalism " of the turn of the century or the "holism" of the 1930s . Gestalt qualities can be characterized by means of the " Ehrenfels criteria". In most cases this means distinguishing between "space gestalt", "time gestalt", "tone gestalt", and "sentence gestalt". As defined by gestalt theory, mental and physical processes correspond. Gestalt can always be defined and understood in concrete terms. In the gestalt the conceptual contradiction between "external" and "internal" is overcome. External phenomena are the manifestations of internal nature. In the fields of pathological anatomy, gestalt theory has direct methodological relevance with regard to the following: a) the concept of homology b) the conceptual idea of what is known as "specific inflammation" c) the theory of stages in minor organ diseases d) the characterization of the various forms of pathomorphosis e) patho-anatomical diagnostics according to the laws of mathematical logic. The relationship between individual sciences and philosophy has always been critical. The individual science and philosophy are mutually obscured from one another. Research into facts and research into essence come together, as in a "gestalt circle", to form a single process of understanding. All lawfulness and order originates from a principle of the mind. The visible manifestation of this principle is the innermost nature of the gestalten . PMID:6426156

Doerr, W

1984-01-01

209

Bad Fish: Human Anatomy and Physiology Edition  

NSDL National Science Digital Library

In this version, developed for a course in human anatomy and physiology, the protagonist of the case, Dr. Westwood, survives an accidental poisoning-not once, but twice. Students read about each incident, applying what they learn in each part of the case to the later sections, and then design a drug to treat the neurotoxin poisoning described in the story. The case comes in three different versions, or editions. This is the Human Anatomy & Physiology Edition, which has a different set of questions than the General Biology Edition or the Cell & Molecular Biology Edition, also in our collection.

Hewlett, James A.

2003-01-01

210

Teaching Anatomy and Physiology Using Computer-Based, Stereoscopic Images  

ERIC Educational Resources Information Center

|Learning real three-dimensional (3D) anatomy for the first time can be challenging. Two-dimensional drawings and plastic models tend to over-simplify the complexity of anatomy. The approach described uses stereoscopy to create 3D images of the process of cadaver dissection and to demonstrate the underlying anatomy related to the speech…

Perry, Jamie; Kuehn, David; Langlois, Rick

2007-01-01

211

Guidelines for Standard Photography in Gross and Clinical Anatomy  

ERIC Educational Resources Information Center

|Photography has a widespread usage in medicine and anatomy. In this review, authors focused on the usage of photography in gross and clinical anatomy. Photography in gross and clinical anatomy is not only essential for accurate documentation of morphological findings but also important in sharing knowledge and experience. Photographs of cadavers…

Barut, Cagatay; Ertilav, Hakan

2011-01-01

212

Learning of Cross-Sectional Anatomy Using Clay Models  

ERIC Educational Resources Information Center

|We incorporated clay modeling into gross anatomy and neuro-anatomy courses to help students understand cross-sectional anatomy. By making clay models, cutting them and comparing cut surfaces to CT and MR images, students learned how cross-sectional two-dimensional images were created from three-dimensional structure of human organs. Most students…

Oh, Chang-Seok; Kim, Ji-Young; Choe, Yeon Hyeon

2009-01-01

213

Teaching Anatomy and Physiology Using Computer-Based, Stereoscopic Images  

NSDL National Science Digital Library

Learning real three-dimensional (3D) anatomy for the first time can be challenging. Two dimensional drawings and plastic models tend to over-simplify the complexity of anatomy. The approach described uses stereoscopy to create 3D images of the process of cadaver dissection and to demonstrate the underlying anatomy related to the speech mechanisms.

Kuehn, David; Perry, Jamie; Langlois, Rick

2007-01-01

214

NCI: SBIR & STTR - Funding Opportunities  

Cancer.gov

If Phase I proves successful, the company may apply for a two-year Phase II award of up to $1 million to further develop the concept, usually to the prototype stage. Proposals are judged competitively on the basis of scientific, technical, and commercial merit. Phase I and II applicants may propose and justify longer periods of time and greater amounts of funds necessary for completion of the project.

215

Endogent: Centre for Anatomy and Invasive Techniques  

Microsoft Academic Search

The invention of new endoscopical techniques for surgery and interventional radiology demand improved training at post- graduate level. The Endogent Centre for Anatomy and Invasive Techniques support these requirements by establishing hands-on practical training courses by using new procedures for cadaver embalming. Cadavers fixed by conventional pro- cedures using formalin for conservation, are of limited use for practical surgical courses

Ingrid Kerckaert; Tom Van Hoof; Piet Pattyn; Katharina D'Herde

2008-01-01

216

The Anatomy of the Medial Patellofemoral Ligament  

Microsoft Academic Search

Background: Fibrous connections and fibrofatty tissue between the layers of the medial retinaculum have prevented accurate definition of the true anatomy of the medial patellofemoral ligament. This has led to confusion about the origin, form, course, and insertion of this structure.Hypothesis: The medial patellofemoral ligament is a discrete structure that can be approached, isolated, and definitively described.Study Design: Descriptive laboratory

James L. Baldwin

2009-01-01

217

The new face of gross anatomy.  

PubMed

The nature of anatomy education has changed substantially over the past decade due to both a new generation of students who learn differently from those of past years and the enormity of advances in anatomical imaging and viewing. At Mount Sinai School of Medicine, our anatomy courses have been designed to meld classic dissection with the tools physicians and surgeons will use tomorrow. We introduce students to the newest technologies available for viewing the body, such as minimally invasive approaches, ultrasonography, three-dimensional visualizations, multi-axial computerized image reconstructions, multi-planar magnetic resonance imaging, and plastinated prosections. Students are given a hands-on, team-building experience operating laparoscopes in the laboratory. A great strength of our program is the important and active participation by faculty from 15 different basic and clinical departments, including several chairs and voluntary faculty. This interdisciplinary approach brings to our students direct, one-on-one encounters or presentations by our finest physicians and surgeons and our core anatomy faculty. In addition, the presence of many teaching assistants drawn from upper classmen and advanced graduate students adds an additional, vibrant dimension. Our anatomy programs for medical/graduate students and postgraduates are structured around three simple principles: (1) it is a privilege to teach, (2) we enlist only passionate teachers, and (3) it is our role to instill appreciation and respect for human form. PMID:12001214

Reidenberg, Joy S; Laitman, Jeffrey T

2002-04-15

218

Professional Storytelling in Clinical Dental Anatomy Teaching  

ERIC Educational Resources Information Center

|The aim of the present work was to see if storytelling in a clinical dental anatomy course would increase student satisfaction. We enhanced teaching by spontaneous storytelling in problem-based learning, in half of the third-year dentistry class. At the end of the course, we administered an anonymous questionnaire to the students in the class,…

Kieser, Jules; Livingstone, Vicki; Meldrum, Alison

2008-01-01

219

Anatomy and biomechanics of the acromioclavicular joint  

Microsoft Academic Search

Knowledge of the anatomy and biomechanics of the acromioclavicular (AC) joint is important for the orthopaedic surgeon. An understanding of the complex soft tissue and bony relationships in the AC joint is critical to achieving operative success. Failure to protect supporting structures during surgery or neglect of preoperatively damaged ligaments can lead to postoperative failure in procedures addressing the AC

Robb Sellards

2004-01-01

220

Anatomy Education Faces Challenges in Pakistan  

NSDL National Science Digital Library

This article explains the difficulties anatomy education in Pakistan is facing. The article highlights the concern about how the changes to the traditional curriculum decreases the quality of education medical students are receiving. Issues discussed are the advantages/disadvantages of PBL learning, lack of trained faculty, lack of cadaver access among others.

2009-07-27

221

Professional Storytelling in Clinical Dental Anatomy Teaching  

ERIC Educational Resources Information Center

The aim of the present work was to see if storytelling in a clinical dental anatomy course would increase student satisfaction. We enhanced teaching by spontaneous storytelling in problem-based learning, in half of the third-year dentistry class. At the end of the course, we administered an anonymous questionnaire to the students in the class,…

Kieser, Jules; Livingstone, Vicki; Meldrum, Alison

2008-01-01

222

Anatomy and Physiology. Revised Teacher Edition.  

ERIC Educational Resources Information Center

|This curriculum guide contains 14 units of instruction for a course in anatomy and physiology for surgical technology students. The units cover the following topics: (1) organization of the body; (2) cells, tissues, and membranes; (3) integumentary system; (4) skeletal system; (5) muscular system; (6) nervous system; (7) special sense organs; (8)…

Hartman, Danene; And Others

223

Shoulder arthroscopy, anatomy and variants - part 1  

Microsoft Academic Search

Arthroscopy is increasingly the modality of choice for interventional procedures in shoulder surgery. It is often learned after a basic grounding in knee arthroscopy, but the wide variation in normal anatomy and unfamiliarity with the 3D arrangement of the joint can easily confuse. This article therefore describes the technicalities of shoulder arthroscopy and introduces the many structures that are encountered.

Simon Boyle; Manuel Haag; David Limb; Laurent Lafosse

2009-01-01

224

US anatomy of the shoulder: Pictorial essay  

Microsoft Academic Search

A thorough knowledge of the anatomy of the shoulder is essential for the assessment of its condition. The purpose of this article is to provide a useful tool for the ultrasound (US) study of this joint. The shoulder girdle and upper arm are made up of a number of muscles and tendons: rotator cuff (supraspinatus, infraspinatus, teres minor and subscapularis),

M. Precerutti; E. Garioni; L. Madonia; F. Draghi

2010-01-01

225

Surgical anatomy of the rat middle ear  

Microsoft Academic Search

This study was designed to aid experimental otologic studies of the rat middle ear. The topographic anatomy of the albino rat middle ear is described. A set of microphotographs with matching illustrations presents the structural details at several surgical exposures. Anatomic differences between the rat, guinea pig, and cat are noted. (Otolaryngol Head Neck Surg 1997;117:438-47.)

RICHARD F. JUDKINS; HONGYAN LI

1997-01-01

226

Anatomy of a Minicourse. Audiovisual Kit.  

ERIC Educational Resources Information Center

This kit explains the use of minicourses at Macquarie University in New South Wales, Australia, which were designed for the inservice training of teachers. The kit contains the script of the audio commentary, a cassette tape, color slides, and a booklet entitled "Anatomy of the Minicourse." The tape briefly describes the minicourses in general and…

Meyer, Rex

227

Anatomy for Dance: An Expanded Design  

Microsoft Academic Search

The field of dance science offers a wealth of information that can enhance a dancer's training, contribute to a dancer's overall health maintenance, and assist in recovery from injury. Most dance curricula today require some study in anatomy and kinesiology as a way to help young dancers take advantage of knowledge gained from research in dance medicine and science. However,

Fritha Pengelly

2010-01-01

228

Anatomy, Medical Education, and Human Ancestral Variation  

ERIC Educational Resources Information Center

|It is argued in this article that the human body both in health and disease cannot be fully understood without adequately accounting for the different levels of human variation. The article focuses on variation due to ancestry, arguing that the inclusion of information pertaining to ancestry in human anatomy teaching materials and courses should…

Strkalj, Goran; Spocter, Muhammad A.; Wilkinson, A. Tracey

2011-01-01

229

Broca's Area: Nomenclature, Anatomy, Typology and Asymmetry  

ERIC Educational Resources Information Center

|In this review, we (i) describe the nomenclature of Broca's area and show how the circumscribed definition of Broca's area is disassociated from Broca's aphasia, (ii) describe in detail how the gross anatomy of Broca's area varies between people, and how the definitions vary between studies, (iii) attempt to reconcile the findings of structural…

Keller, Simon S.; Crow, Timothy; Foundas, Anne; Amunts, Katrin; Roberts, Neil

2009-01-01

230

Teaching Cell Anatomy with a Fabric Model  

ERIC Educational Resources Information Center

|Middle schoolers are often first introduced to detailed cellular anatomy through one-dimensional drawings in basic life science books, fill-in-the blank handouts accompanied by notes from the teacher, or desktop hard-plastic commercial models that resemble giant lollipops. One of the most important, yet difficult, life science concepts for…

Kluka, Michelle

2005-01-01

231

Testing to Enhance Retention in Human Anatomy  

ERIC Educational Resources Information Center

|Recent work in cognitive psychology has shown that repeatedly testing one's knowledge is a powerful learning aid and provides substantial benefits for retention of the material. To apply this in a human anatomy course for medical students, 39 fill-in-the-blank quizzes of about 50 questions each, one for each region of the body, and four about the…

Logan, Jessica M.; Thompson, Andrew J.; Marshak, David W.

2011-01-01

232

The anatomy of banking firm financial condition  

Microsoft Academic Search

This study employs factor analysis to develop a conceptual model of bank financial condition from financial ratios and other characteristics in Nigerian banking. It paints the anatomy of the phenomenon in a conceptual model around the prudential application of market power and market presence to transform deposit mobilisation, under a given macro-economic condition, into earnings quality with capital boosting confidence.

Jonathan Njoku; Eno L. Inanga

2010-01-01

233

Angiographic Anatomy of the Laterocavernous Sinus  

Microsoft Academic Search

BACKGROUND AND PURPOSE: The laterocavernous sinus (LCS) has recently been rec- ognized as one of the major drainage pathways of the superficial middle cerebral vein (SMCV). Our purpose was to investigate the drainage pattern of the SMCV, with special emphasis on the angiographic anatomy of the LCS. METHODS: The drainage pathways of the SMCV were evaluated prospectively on 100 se-

Philippe Gailloud; Diego San Millan Ruiz; Michel Muster; Kieran J. Murphy; Jean H. D. Fasel; Daniel A. Rufenacht

2000-01-01

234

Hypophyseal region — anatomy of the operative approaches  

Microsoft Academic Search

Summary Landmarks and measurements for the transnasal approach (apertura piriformis, distance to the apertura sinus sphenoidalis) in children and adults are given. Included is the anatomy of the nasal septum, its vessels and nerves. The ostium of the sphenoid sinus, its development, types and dimensions are described. Also shown are the hypophyseal capsule, the hypophyseal vessels and the hypophyseal fossa

Johannes Lang; F. R. Germany

1985-01-01

235

Surgical anatomy of the anterior clinoid process  

Microsoft Academic Search

We studied the surgical anatomy of the anterior clinoid process (ACP) and its adjacent structures in cadaver heads. We paid special attention to the anatomical relationships between the ACP and adjacent structures to determine the surgical landmarks for safe anterior clinoidectomy. Thirty-five cadaver heads were dissected and the ACP regions were examined in 55 skull sides. We observed that in

Phuong Huynh-Le; Yoshihiro Natori; Tomio Sasaki

2004-01-01

236

Neuromodulators: available agents, physiology, and anatomy.  

PubMed

Neuromodulators have risen to the forefront of aesthetic medicine. By reversibly relaxing target muscles, neuromodulators exhibit their effect by softening hyperfunctional lines. An understanding of their physiology, relevant facial anatomy, and current agents is imperative for a successful aesthetic practice. PMID:22205524

Nettar, Kartik; Maas, Corey

2011-12-28

237

"Digit anatomy": a new technique for learning anatomy using motor memory.  

PubMed

Gestural motions of the hands and fingers are powerful tools for expressing meanings and concepts, and the nervous system has the capacity to retain multiple long-term motor memories, especially including movements of the hands. We developed many sets of successive movements of both hands, referred to as "digit anatomy," and made students practice the movements which express (1) the aortic arch, subclavian, and thoracoacromial arteries and their branches, (2) the celiac trunk, superior mesenteric artery and their branches, and formation of the portal vein, (3) the heart and the coronary arteries, and (4) the brachial, lumbar, and sacral plexuses. A feedback survey showed that digit anatomy was helpful for the students not only in memorizing anatomical structures but also in understanding their functions. Out of 40 students, 34 of them who learned anatomy with the help of digit anatomy were "very satisfied" or "generally satisfied" with this new teaching method. Digit anatomy that was used to express the aortic arch, subclavian, and thoracoacromial arteries and their branches was more helpful than those representing other structures. Although the movements of digit anatomy are expected to be remembered longer than the exact meaning of each movement, invoking the motor memory of the movement may help to make relearning of the same information easier and faster in the future. PMID:21538938

Oh, Chang-Seok; Won, Hyung-Sun; Kim, Kyong-Jee; Jang, Dong-Su

2011-04-27

238

Anatomy of the Temporal Lobe  

PubMed Central

Only primates have temporal lobes, which are largest in man, accommodating 17% of the cerebral cortex and including areas with auditory, olfactory, vestibular, visual and linguistic functions. The hippocampal formation, on the medial side of the lobe, includes the parahippocampal gyrus, subiculum, hippocampus, dentate gyrus, and associated white matter, notably the fimbria, whose fibres continue into the fornix. The hippocampus is an inrolled gyrus that bulges into the temporal horn of the lateral ventricle. Association fibres connect all parts of the cerebral cortex with the parahippocampal gyrus and subiculum, which in turn project to the dentate gyrus. The largest efferent projection of the subiculum and hippocampus is through the fornix to the hypothalamus. The choroid fissure, alongside the fimbria, separates the temporal lobe from the optic tract, hypothalamus and midbrain. The amygdala comprises several nuclei on the medial aspect of the temporal lobe, mostly anterior the hippocampus and indenting the tip of the temporal horn. The amygdala receives input from the olfactory bulb and from association cortex for other modalities of sensation. Its major projections are to the septal area and prefrontal cortex, mediating emotional responses to sensory stimuli. The temporal lobe contains much subcortical white matter, with such named bundles as the anterior commissure, arcuate fasciculus, inferior longitudinal fasciculus and uncinate fasciculus, and Meyer's loop of the geniculocalcarine tract. This article also reviews arterial supply, venous drainage, and anatomical relations of the temporal lobe to adjacent intracranial and tympanic structures.

Kiernan, J. A.

2012-01-01

239

Web-based stereoscopic visualization for the global anatomy classroom.  

PubMed

Many projects have focused on the improvement of virtual education. We have contributed with the global virtual anatomy course for teaching students in multiple locations with stereoscopic volume rendering, audio/video conferencing and additional materials. This year we focused on further simplifying the deployment of the classroom by using the new collaborative and web-based visualization system CoWebViz, to transfer stereoscopic visualization to the classrooms. Besides the necessary hardware installations for stereoscopy, only a web browser is necessary to view and to interact with the remote 3D stereo visualization. This system proved stable, gave higher quality images and increased ease of deployment. Its success within our classroom at the University of Chicago and Cardiff University has motivated us to continue CoWebViz development. PMID:21335801

Kaspar, Mathias; Dech, Fred; Parsad, Nigel M; Silverstein, Jonathan C

2011-01-01

240

Animated PowerPoint as a tool to teach anatomy.  

PubMed

Anatomy is a visual science. For centuries, anatomic information has been conveyed through drawings that have been presented to students through every available medium. The projection of animated images from a computer is a medium that offers great promise in effecting improved communication of anatomic information. Using Microsoft PowerPoint software, we have developed animated presentations for all of our lectures in Gross and Developmental Anatomy. As a starting point, we scan pen-and-ink drawings to create a digital image. The image may be edited and manipulated in an image processing program. Next, the image is imported into a PowerPoint slide where it is labeled and otherwise enhanced (arteries overlaid with red color, veins in blue, etc.) and the enhancements are animated, as we describe here step by step. For the lecture, the file is loaded on a server that is accessible through a network from a computer in the lecture hall. The output is directed to a video projector and the PowerPoint presentation is projected in the "Slide Show" mode. We use a wireless mouse that allows us to control the presentation from anywhere in the room. Before the lecture, students are provided with the same unlabeled drawings as handouts, and during the lecture the students are actively engaged in labeling the drawings and making related notes. After the lecture, the file is saved in HTML format and posted on our course web site where students can access the slides. Evaluation by the students at the end of the course demonstrated that this style of presentation was very favorably received. PMID:10815813

Carmichael, S W; Pawlina, W

2000-04-15

241

NCI Announces Creation of Early Detection Research Network: Comprehensive Initiative Will Develop and Validate Early Detection Markers for Cancer  

Cancer.gov

Advances in cancer research, including programs such as the Cancer Genome Anatomy Project and the Director's Challenge for Molecular Diagnostics, will aid in the discovery of a variety of molecules, proteins, genes, and other biological substances that researchers believe may be the earliest warning signals that normal cells are on the road to becoming cancerous

242

The history of anatomy in Persia.  

PubMed

The study of human anatomy can be found throughout the rich history of Persia. For thousands of years, morphological descriptions derived from this part of the world have contributed to and have helped form our current anatomical knowledge base. In this article we review the major influential Persian periods and the individuals who have contributed to the development of anatomy. We have divided the history of Persia into five eras: (1) the period of the Elamites, Medes, early Persians and Babylonians (10th millennium to 6th century BC); (2) following the establishment of the Persian Empire (6th century BC) to the 7th century AD; (3) after the Islamic conquest of Persia to the ascendency of Baghdad (7th to 13th century AD); (4) from the Mongol invasion of Persia to the foundations of modern anatomy (13th to 18th century AD); and (5) modern Persia/Iran (18th century AD to present). Evidence indicates that human dissection was commonplace in the first era, which led to a disciplined practice of surgery in the centuries leading to the foundation of the Persian Empire. By the emergence of Zoroastrianism in the Persian Empire, the microcosm theory was widely used to understand internal anatomy in relation to the external universe. The world's first cosmopolitan university and hospital were built in Gondishapur, south-western Persia, in the third century AD. Greek and Syriac knowledge influenced the second era. With the gradual ruin of Gondishapur and the foundation of Baghdad following the Islamic conquest of Persia (637-651 AD), a great movement took place, which led to the flourishing of the so-called Middle Age or Islamic Golden Age. Of the influential anatomists of this period, Mesue (777-857 AD), Tabbari (838-870 AD), Rhazes (865-925 AD), Joveini (?-983 AD), Ali ibn Abbas (930-994 AD), Avicenna (980-1037 AD) and Jorjani (1042-1137 AD) all hailed from Persia. There is evidence in the Persian literature as to the direct involvement of these scholars in human dissection. Syro-Indian, Byzantine, Greek, Chinese and Arabic knowledge all influenced the third era. In the fourth period, the first colour illustrated anatomical text (by Mansur, 14th century AD) was compiled. Chinese and Indian anatomical styles were embraced, though there was a strong religious siege of anatomy late in this era. By the 19th century, Persia had entered a new era of modernizing movements and academic contact with the West through the reforms of Mirza Tagi Khan Amir Kabir. Knowledge of anatomy for this region in the 20th century was greatly influenced by Europe and America. PMID:17428200

Shoja, Mohammadali M; Tubbs, R Shane

2007-04-01

243

An NCI perspective on creating sustainable biospecimen resources.  

PubMed

High-quality biospecimens with appropriate clinical annotation are critical in the era of personalized medicine. It is now widely recognized that biospecimen resources need to be developed and operated under established scientific, technical, business, and ethical/legal standards. To date, such standards have not been widely practiced, resulting in variable biospecimen quality that may compromise research efforts. The National Cancer Institute (NCI) Office of Biorepositories and Biospecimen Research (OBBR) was established in 2005 to coordinate NCI's biospecimen resource activities and address those issues that affect access to the high-quality specimens and data necessary for its research enterprises as well as the broader translational research field. OBBR and the NCI Biorepository Coordinating Committee developed NCI's "Best Practices for Biospecimen Resources" after consultation with a broad array of experts. A Biospecimen Research Network was established to fund research to develop additional evidence-based practices. Although these initiatives will improve the overall availability of high-quality specimens and data for cancer research, OBBR has been authorized to implement a national biobanking effort, cancer HUman Biobank (caHUB). caHUB will address systematically the gaps in knowledge needed to improve the state-of-the-science and strengthen the standards for human biobanking. This commentary outlines the progressive efforts by NCI in technical, governance, and economic considerations that will be important as the new caHUB enterprise is undertaken. PMID:21672889

Vaught, Jimmie; Rogers, Joyce; Myers, Kimberly; Lim, Mark David; Lockhart, Nicole; Moore, Helen; Sawyer, Sherilyn; Furman, Jeffrey L; Compton, Carolyn

2011-01-01

244

The emerging discipline of Computational Functional Anatomy  

PubMed Central

Computational Functional Anatomy (CFA) is the study of functional and physiological response variables in anatomical coordinates. For this we focus on two things: (i) the construction of bijections (via diffeomorphisms) between the coordinatized manifolds of human anatomy, and (ii) the transfer (group action and parallel transport) of functional information into anatomical atlases via these bijections. We review advances in the unification of the bijective comparison of anatomical submanifolds via point-sets including points, curves and surface triangulations as well as dense imagery. We examine the transfer via these bijections of functional response variables into anatomical coordinates via group action on scalars and matrices in DTI as well as parallel transport of metric information across multiple templates which preserves the inner product.

Miller, Michael I.; Qiu, Anqi

2010-01-01

245

The distal venous anatomy of the finger.  

PubMed

An exhaustive anatomic dissection of all of the veins of the finger distal to the proximal interphalangeal joint was done. More than 3200 segments of veins were individually dissected out, measured, and recorded. From this survey new schematic diagrams have been drawn emphasizing the pertinent venous anatomy at the proximal, distal interphalangeal joints and eponychial levels. Suggestions are made for regions that are apt to have the largest vessels available for anastomosis. PMID:2022842

Smith, D O; Oura, C; Kimura, C; Toshimori, K

1991-03-01

246

The Foundational Model of Anatomy Ontology  

Microsoft Academic Search

Anatomy is the structure of biological organisms. The term also denotes the scientific discipline devoted to the study of\\u000a anatomical entities and the structural and developmental relations that obtain among these entities during the lifespan of\\u000a an organism. Anatomical entities are the independent continuants of biomedical reality on which physiological and disease\\u000a processes depend, and which, in response to etiological

Cornelius Rosse; José L. V. Mejino Jr

247

A Gross Anatomy Ontology for Hymenoptera  

PubMed Central

Hymenoptera is an extraordinarily diverse lineage, both in terms of species numbers and morphotypes, that includes sawflies, bees, wasps, and ants. These organisms serve critical roles as herbivores, predators, parasitoids, and pollinators, with several species functioning as models for agricultural, behavioral, and genomic research. The collective anatomical knowledge of these insects, however, has been described or referred to by labels derived from numerous, partially overlapping lexicons. The resulting corpus of information—millions of statements about hymenopteran phenotypes—remains inaccessible due to language discrepancies. The Hymenoptera Anatomy Ontology (HAO) was developed to surmount this challenge and to aid future communication related to hymenopteran anatomy. The HAO was built using newly developed interfaces within mx, a Web-based, open source software package, that enables collaborators to simultaneously contribute to an ontology. Over twenty people contributed to the development of this ontology by adding terms, genus differentia, references, images, relationships, and annotations. The database interface returns an Open Biomedical Ontology (OBO) formatted version of the ontology and includes mechanisms for extracting candidate data and for publishing a searchable ontology to the Web. The application tools are subject-agnostic and may be used by others initiating and developing ontologies. The present core HAO data constitute 2,111 concepts, 6,977 terms (labels for concepts), 3,152 relations, 4,361 sensus (links between terms, concepts, and references) and over 6,000 text and graphical annotations. The HAO is rooted with the Common Anatomy Reference Ontology (CARO), in order to facilitate interoperability with and future alignment to other anatomy ontologies, and is available through the OBO Foundry ontology repository and BioPortal. The HAO provides a foundation through which connections between genomic, evolutionary developmental biology, phylogenetic, taxonomic, and morphological research can be actualized. Inherent mechanisms for feedback and content delivery demonstrate the effectiveness of remote, collaborative ontology development and facilitate future refinement of the HAO.

Yoder, Matthew J.; Miko, Istvan; Seltmann, Katja C.; Bertone, Matthew A.; Deans, Andrew R.

2010-01-01

248

Michelangelo: art, anatomy, and the kidney.  

PubMed

Michelangelo (1475-1564) had a life-long interest in anatomy that began with his participation in public dissections in his early teens, when he joined the court of Lorenzo de' Medici and was exposed to its physician-philosopher members. By the age of 18, he began to perform his own dissections. His early anatomic interests were revived later in life when he aspired to publish a book on anatomy for artists and to collaborate in the illustration of a medical anatomy text that was being prepared by the Paduan anatomist Realdo Colombo (1516-1559). His relationship with Colombo likely began when Colombo diagnosed and treated him for nephrolithiasis in 1549. He seems to have developed gouty arthritis in 1555, making the possibility of uric acid stones a distinct probability. Recurrent urinary stones until the end of his life are well documented in his correspondence, and available documents imply that he may have suffered from nephrolithiasis earlier in life. His terminal illness with symptoms of fluid overload suggests that he may have sustained obstructive nephropathy. That this may account for his interest in kidney function is evident in his poetry and drawings. Most impressive in this regard is the mantle of the Creator in his painting of the Separation of Land and Water in the Sistine Ceiling, which is in the shape of a bisected right kidney. His use of the renal outline in a scene representing the separation of solids (Land) from liquid (Water) suggests that Michelangelo was likely familiar with the anatomy and function of the kidney as it was understood at the time. PMID:10720972

Eknoyan, G

2000-03-01

249

Floral development and anatomy of Salvadoraceae  

PubMed Central

Background and Aims This study is an investigation into the floral development and anatomy of two genera of the small family Salvadoraceae, which belongs to the Brassicales in a clade with Batis and Koeberlinia. Salvadoraceae remains little known, despite its wide distribution in arid areas of the globe. Floral morphological data are scarce, and information on floral anatomy is limited to a single study, although morphological and anatomical characters are now used increasingly as a counterpart of molecular data. There remain a number of controversial morphological questions, such as the fusion of the petals, the number of carpels and the nature of the nectaries. Methods Floral anatomy and ontogeny were studied in two species of Salvadora and one species of Dobera. Only for S. persica could a full floral developmental sequence be done. Key Results The floral development demonstrates that the ovary of Salvadoraceae is basically bicarpellate and pseudomonomerous with a single locule and parietal placenta. The ovary of Dobera resembles Azima tetracantha in the presence of a false apical septum. Evidence for a staminodial nature of the nectaries is not decisive. In Salvadora petals and stamens are lifted by a short hypanthium. Conclusions Salvadoraceae share several morphological and developmental synapomorphies with Batis (Bataceae) and possibly Koeberlinia (Koeberliniaceae), supporting their close relationship as indicated by molecular phylogeny.

Ronse De Craene, Louis; Wanntorp, Livia

2009-01-01

250

Robert Knox and the anatomy of beauty.  

PubMed

Robert Knox (1791-1862) is typically remembered as the Edinburgh anatomist to whom the murderers Burke and Hare sold the bodies of their victims. This association brought Knox infamy and damaged his life and career. Before the Burke and Hare scandal, Knox was one of the most famous, original and influential anatomists in Britain. He was also something of a dandy with a sophisticated appreciation of the visual arts. His most significant writings on artistic subjects were his books A Manual of Artistic Anatomy and Great Artists and Great Anatomists: A Biographical and Philosophical Study. Knox's interesting and independently minded opinions on the central artistic questions of his day were taken seriously by his contemporaries. His demotion in the official history of anatomy following his involvement with Burke and Hare, however, also removed him from the history of art theory in 19th century Britain. Knox was such a magnetic and impressive figure, though, that he has to be brought back to his era and his era is not complete without him. This paper discusses how Knox's writings on anatomy and biology shaped his contributions to art theory. It is a first step towards returning Knox, the art theorist, to the cultural life of 19th century Britain. PMID:21593248

Neher, Allister

2011-06-01

251

Functional anatomy of the premaxillary area.  

PubMed

Although the gross anatomy of the nasal septum is well-understood, the exact anatomy of its ventrocaudal or premaxillary area is not. More precisely, there is some confusion about the course of the perichondrial and periosteal fibers in this particular region. This paper considers the detailed anatomy of the chondro-spinal and chondro-premaxillary junction. Six cadaver noses were sectioned in the coronal (n = 4) or the transverse (n = 2) plane. The sections were stained according to the Mallory-Cason and the Haematoxylin-Eosine method and examined by light microscopy. At the chondrospinal junction a relatively wide suture line filled with loose connective tissue fibers was found. The caudal margin of the cartilaginous septum is flanked by paraseptal cartilages. These broaden the septal base to fit onto the flat cranial surface of the anterior nasal spine. At the chondro-premaxillary junction a narrow suture with several crossing fibers between the perichondrium and periosteum was seen. Paraseptal cartilages, surrounded by their own perichondrium, cover the periphery of this area. It was concluded that the chondro-spinal junction provides stabilization while allowing some mobility of the septum, whereas the chondro-premaxillary complex stabilizes the septum without allowing mobility. PMID:10229977

Hafkamp, H C; Bruintjes, T D; Huizing, E H

1999-03-01

252

Matching arthropod anatomy ontologies to the Hymenoptera Anatomy Ontology: results from a manual alignment  

PubMed Central

Matching is an important step for increasing interoperability between heterogeneous ontologies. Here, we present alignments we produced as domain experts, using a manual mapping process, between the Hymenoptera Anatomy Ontology and other existing arthropod anatomy ontologies (representing spiders, ticks, mosquitoes and Drosophila melanogaster). The resulting alignments contain from 43 to 368 mappings (correspondences), all derived from domain-expert input. Despite the many pairwise correspondences, only 11 correspondences were found in common between all ontologies, suggesting either major intrinsic differences between each ontology or gaps in representing each group’s anatomy. Furthermore, we compare our findings with putative correspondences from Bioportal (derived from LOOM software) and summarize the results in a total evidence alignment. We briefly discuss characteristics of the ontologies and issues with the matching process. Database URL: http://purl.obolibrary.org/obo/hao/2012-07-18/arthropod-mappings.obo

Bertone, Matthew A.; Miko, Istvan; Yoder, Matthew J.; Seltmann, Katja C.; Balhoff, James P.; Deans, Andrew R.

2013-01-01

253

Matching arthropod anatomy ontologies to the Hymenoptera Anatomy Ontology: results from a manual alignment.  

PubMed

Matching is an important step for increasing interoperability between heterogeneous ontologies. Here, we present alignments we produced as domain experts, using a manual mapping process, between the Hymenoptera Anatomy Ontology and other existing arthropod anatomy ontologies (representing spiders, ticks, mosquitoes and Drosophila melanogaster). The resulting alignments contain from 43 to 368 mappings (correspondences), all derived from domain-expert input. Despite the many pairwise correspondences, only 11 correspondences were found in common between all ontologies, suggesting either major intrinsic differences between each ontology or gaps in representing each group's anatomy. Furthermore, we compare our findings with putative correspondences from Bioportal (derived from LOOM software) and summarize the results in a total evidence alignment. We briefly discuss characteristics of the ontologies and issues with the matching process. PMID:23303300

Bertone, Matthew A; Mikó, István; Yoder, Matthew J; Seltmann, Katja C; Balhoff, James P; Deans, Andrew R

2013-01-09

254

Hilar cholangiocarcinoma—surgical anatomy and curative resection  

Microsoft Academic Search

We have studied the surgical anatomy of the intrahepatic bile duct, hepatic hilus, and caudate lobe based on intraoperative\\u000a findings and selective cholangiography of surgical patients and resected specimens, and have established the cholangiographic\\u000a anatomy of the intrahepatic subsegmental bile duct. Thorough knowledge of the three-dimensional anatomy of the subsegmental\\u000a bile duct, hepatic hilus, and caudate lobe is indispensable for

Yuji Nimura; Naokazu Hayakawa; Junichi Kamiya; Satoshi Kondo; Masato Nagino; Michio Kanai

1995-01-01

255

The NCI Drug Information System. 4. Inventory and Shipping Modules.  

PubMed

The Inventory/Shipping package of the NCI Drug Information System (DIS) is designed to support all inventory and shipping operations associated with the testing by the NCI of large numbers of chemicals for anticancer activity. Two major databases, an Inventory database and a Shipping History database, contain all of the data associated with these operations. Software that supports the operations in an online interactive manner also provides for the accessing and updating of these databases as necessary. Special hardware in the form of barcode reader/printers and digital balances is also interfaced to the system to improve the efficiency of the operations. PMID:3818818

Milne, G W; Miller, J A; Hoover, J R

1986-11-01

256

Atlas of fetal sectional anatomy with ultrasound and magnetic resonance imaging  

SciTech Connect

Here is an atlas of sectional anatomy for the fetus featuring correlated anatomy and imaging, transverse coronal and sagittal views, a guide to development of the brain, cardiac anatomy in standard plans of study and, over 280 illustrations.

Isaacson, G.; Mintz, M.C.; Crelin, E.S.

1986-01-01

257

NCI Funded Research Portfolio - 5P30CA016359-33 Detail  

Cancer.gov

The Yale Cancer Center (YCC) was designated as an NCI Comprehensive Cancer Center in 1974. YCC has elected to profoundly alter its structure to better facilitate clinical translation of its abundant scientific strengths. A particularly important component, taken in consultation with the NCI, was relocation of operational control of Medical Oncology to YCC, to augment Center influence over the Clinical Trials Program. An administrative 3-year extension from the NCI enabled these changes.

258

"Digit Anatomy": A New Technique for Learning Anatomy Using Motor Memory  

ERIC Educational Resources Information Center

|Gestural motions of the hands and fingers are powerful tools for expressing meanings and concepts, and the nervous system has the capacity to retain multiple long-term motor memories, especially including movements of the hands. We developed many sets of successive movements of both hands, referred to as "digit anatomy," and made students…

Oh, Chang-Seok; Won, Hyung-Sun; Kim, Kyong-Jee; Jang, Dong-Su

2011-01-01

259

The Virtual Anatomy Laboratory: Usability Testing to Improve an Online Learning Resource for Anatomy Education  

ERIC Educational Resources Information Center

|An increasing number of instructors are seeking to provide students with online anatomy resources. Many researchers have attempted to identify associations between resource use and student learning but few studies discuss the importance of usability testing in resource design and modification. Usability testing provides information about ease of…

Doubleday, Eldridge G.; O'Loughlin, Valerie D.; Doubleday, Alison F.

2011-01-01

260

Observations by a University Anatomy Teacher and a Suggestion for Curricular Change: Integrative Anatomy for Undergraduates  

ERIC Educational Resources Information Center

|The observation that anatomical course offerings have decreased in undergraduate biology curricula is supported by a survey of undergraduate institutions in the state of Washington. This reduction, due partially to increased emphasis in other areas of the biology curriculum, along with the lack of anatomy prerequisites for admission to most…

Darda, David M.

2010-01-01

261

An ontology of human developmental anatomy  

PubMed Central

Human developmental anatomy has been organized as structured lists of the major constituent tissues present during each of Carnegie stages 1–20 (E1–E50, ?8500 anatomically defined tissue items). For each of these stages, the tissues have been organized as a hierarchy in which an individual tissue is catalogued as part of a larger tissue. Such a formal representation of knowledge is known as an ontology and this anatomical ontology can be used in databases to store, organize and search for data associated with the tissues present at each developmental stage. The anatomical data for compiling these hierarchies comes from the literature, from observations on embryos in the Patten Collection (Ann Arbor, MI, USA) and from comparisons with mouse tissues at similar stages of development. The ontology is available in three versions. The first gives hierarchies of the named tissues present at each Carnegie stage (http://www.ana.ed.ac.uk/anatomy/database/humat/) and is intended to help analyse both normal and abnormal human embryos; it carries hyperlinked notes on some ambiguities in the literature that have been clarified through analysing sectioned material. The second contains many additional subsidiary tissue domains and is intended for handling tissue-associated data (e.g. gene-expression) in a database. This version is available at the humat site and at http://genex.hgu.mrc.ac.uk/Resources/intro.html/), and has been designed to be interoperable with the ontology for mouse developmental anatomy, also available at the genex site. The third gives the second version in GO ontology syntax (with standard IDs for each tissue) and can be downloaded from both the genex and the Open Biological Ontology sites (http://obo.sourceforge.net/)

Hunter, Amy; Kaufman, Matthew H; McKay, Angus; Baldock, Richard; Simmen, Martin W; Bard, Jonathan B L

2003-01-01

262

A reappraisal of adult thoracic surface anatomy.  

PubMed

Accurate surface anatomy is essential for safe clinical practice. Numerous inconsistencies in clinically important surface markings exist between and within anatomical reference texts. The aim of this study was to investigate key thoracic surface anatomical landmarks in vivo using computed tomographic (CT) imaging. High-resolution thoracic CT scans from 153 supine adults (mean age 63, range 19-89 years; 53% female) taken at end tidal inspiration were analyzed by dual consensus reporting to determine the surface anatomy of the sternal angle, central veins, heart, lungs, and diaphragm. Patients with kyphosis/scoliosis, distorting space-occupying lesions, or visceromegaly were excluded. The position of the cardiac apex, formation of the brachiocephalic veins, and vertebral levels of the sternal angle, xiphisternal joint, and aortic hiatus were consistent with commonly accepted surface markings although there was a wide range of normal variation. In contrast, common surface markings were markedly inaccurate for the following: the position of the tracheal bifurcation, aortic arch, and azygos vein termination (below the plane of the sternal angle at T5-T6 vertebral level in most individuals); the superior vena cava/right atrial junction (most often behind the fourth costal cartilage); the lower border of the lung (adjacent to T12 vertebra posteriorly); and the level at which the inferior vena cava and esophagus traverse the diaphragm (T11 in most). Surface anatomy must be reappraised using modern imaging in vivo if it is to be evidence based and fit for purpose. The effects of gender, age, posture, respiration, build, and ethnicity also deserve greater emphasis. PMID:22576938

Mirjalili, S Ali; Hale, Samuel J M; Buckenham, Tim; Wilson, Ben; Stringer, Mark D

2012-05-10

263

Dorsal forearm muscles: US anatomy Pictorial Essay.  

PubMed

THE DORSAL COMPARTMENT OF THE FOREARM CONTAINS NINE MUSCLES: four belong to the superficial group (extensor digitorum communis, extensor digiti minimi, extensor carpi ulnaris and anconeus) and five to the deep group (supinator, abductor longus, extensor pollicis brevis, extensor pollicis longus, and extensor indices). Of these nine muscles the following details are considered: origin, course, distal insertion and their anatomical connection with those structures which are most often affected by pathologies. The radiologist must have a thorough knowledge of this complex topographic anatomy in order to perform ultrasound (US) and magnetic resonance imaging (MRI) examinations and correctly interpret the images. PMID:23396199

Precerutti, M; Garioni, E; Ferrozzi, G

2010-07-24

264

[Nose surgical anatomy in six aesthetic subunits].  

PubMed

The nose is a complex entity, combining aesthetic and functional roles. Descriptive anatomy is a fundamental science that it can be difficult to relate directly to our daily surgical activity. Reasoning in terms of aesthetic subunits to decide on his actions appeared to us so obvious. The aim of this paper is to resume the anatomical bases relevant to our daily practice in order to fully apprehend the restorative or cosmetic procedures. We discuss the limits of the systematization of these principles in nasal oncology. PMID:22699003

Chaput, B; Lauwers, F; Lopez, R; Saboye, J; André, A; Grolleau, J-L; Chavoin, J-P

2012-06-13

265

[Functional and mechanical anatomy of arm elevation].  

PubMed

Experimental work on the functional anatomy of the shoulder has involved a study of the conditions involved in elevation of the arm. Movements of the upper limb are organised round a very special alignment of the scapulo-humeral joint whose geometric features and exact position have been determined. The ligaments of the joint play a major role in the controlling the attainment of this alignment. The value of this alignment in the physiology of the shoulder is demonstrated. A new terminology of shoulder movement is suggested. PMID:3175102

Gagey, O; Bonfait, H; Gillot, C; Mazas, F

1988-01-01

266

NCI Announces Integrated Implementation Plan to Fight Lung Cancer  

Cancer.gov

The NCI today announced an integrated effort to reduce the suffering and death due to lung cancer by 2015. Each year, 160,000 people in the United States die from lung cancer, making it the number one cause of cancer deaths in this country.

267

NCI-designated Cancer Centers: dedicated to research  

Cancer.gov

The National Cancer Institute came into being in 1937, and in the years following became the first disease-focused institute of the National Institutes of Health. Yet, what is widely considered the modern history of the NCI began with Congressional passage and Presidential signing of the National Cancer Act of 1971.

268

NCI-CCR Pediatric Oncology Branch - Clinical Programs: Psychosocial  

Cancer.gov

Research is another critical component of the psychosocial program. Our research studies are designed to learn how to best help patients and their families prepare for, adjust to, and cope with the effects of cancer and other related medical conditions while enrolled on research protocols in several NCI Branches and NIH Institutes.

269

2013 FRIENDS-OF-NCI-EGRP News Flashes  

Cancer.gov

The following is an archive of listserv announcements, or "News Flashes" sent by the Epidemiology and Genetics Research Program (EGRP) to FRIENDS-OF-NCI-EGRP LISTSERV subscribers. These occasional announcements communicate information about funding opportunities related to cancer epidemiology, grantsmanship issues, research resources, and other relevant news.

270

2011 FRIENDS-OF-NCI-EGRP News Flashes  

Cancer.gov

The following is an archive of listserv announcements, or "News Flashes" sent by the Epidemiology and Genetics Research Program (EGRP) to FRIENDS-OF-NCI-EGRP LISTSERV subscribers. These occasional announcements communicate information about funding opportunities related to cancer epidemiology, grantsmanship issues, research resources, and other relevant news.

271

2008 FRIENDS-OF-NCI-EGRP News Flashes  

Cancer.gov

The following is an archive of listserv announcements, or "News Flashes" sent by the Epidemiology and Genetics Research Program (EGRP) to FRIENDS-OF-NCI-EGRP LISTSERV subscribers. These occasional announcements communicate information about funding opportunities related to cancer epidemiology, grantsmanship issues, research resources, and other relevant news.

272

NCI Funded Research Portfolio - ZIA SC 010100 Detail  

Cancer.gov

The Neuro-Oncology Branch (NOB) of the National Cancer Institute (NCI) for the past six years has been collecting and characterizing nearly one thousand gliomas of every grade and histopathological class (oligodendrogliomas, astrocytomas, ependymomas) under a multi-institutional study conceived of, written by and chaired by H. Fine (NABTC protocol 01-07).

273

2010 FRIENDS-OF-NCI-EGRP News Flashes  

Cancer.gov

The following is an archive of listserv announcements, or "News Flashes" sent by the Epidemiology and Genetics Research Program (EGRP) to FRIENDS-OF-NCI-EGRP LISTSERV subscribers. These occasional announcements communicate information about funding opportunities related to cancer epidemiology, grantsmanship issues, research resources, and other relevant news.

274

2012 FRIENDS-OF-NCI-EGRP News Flashes  

Cancer.gov

The following is an archive of listserv announcements, or "News Flashes" sent by the Epidemiology and Genetics Research Program (EGRP) to FRIENDS-OF-NCI-EGRP LISTSERV subscribers. These occasional announcements communicate information about funding opportunities related to cancer epidemiology, grantsmanship issues, research resources, and other relevant news.

275

NCI/All-Ireland Consortium Announces First Cancer Statistics  

Cancer.gov

The Ireland-Northern Ireland-NCI (National Cancer Institute) Cancer Consortium has announced publication of the first report on cancer statistics for the island of Ireland, a collaborative effort that marks another milestone for the 2-year-old consortium.

276

NCI\\/MRI Chemical Carcinogen Reference Standard Repository  

Microsoft Academic Search

The National Cancer Institute repository was established nearly 18 years ago to provide a centralized source of well-characterized standards for distribution to the carcinogenesis research community. The NCI repository at Midwest Research Institute consists of over 800 chemicals. During the last fiscal year, 237 orders for characterized standards, consisting of 837 aliquots of 82 chemicals, were received; 185 orders were

Alice P. Clark; Carol F. Blevins; David G. Longfellow; Harold E. Seifried

1994-01-01

277

NCI Files Opposition to Protect "5 A DAY" Logo  

Cancer.gov

On April 9, 2003, the National Cancer Institute (NCI) filed an opposition with the U.S. Patent and Trademark Office to protect the trademark for its "5 A DAY" campaign, which encourages Americans to eat five or more servings of fruits and vegetables every day for better health

278

NCI Announces New Initiative on Energetics and Cancer  

Cancer.gov

NCI today announced the funding of a new initiative that will expand its efforts to understand the relationship between obesity and cancer. The Transdisciplinary Research on Energetics and Cancer (TREC) initiative will support a diverse team of scientists from across the United States.

279

It's Difficult to Change the Way We Teach: Lessons from the Integrative Themes in Physiology Curriculum Module Project  

ERIC Educational Resources Information Center

|The Integrative Themes in Physiology (ITIP) project was a National Science Foundation-funded collaboration between the American Physiological Society (APS) and the Human Anatomy and Physiology Society (HAPS). The project goal was to create instructional resources that emphasized active learning in undergraduate anatomy and physiology classrooms.…

Silverthorn, Dee U.; Thorn, Patti M.; Svinicki, Marilla D.

2006-01-01

280

Anatomy "Steeplechase" Online: Necessity Sometimes Is the Catalyst for Innovation  

ERIC Educational Resources Information Center

|In most medical schools, summative practical examination in Anatomy usually takes the format of a "steeplechase" ("spotters" or "bell ringers") conducted in the gross anatomy laboratory using cadaveric material and prosected specimens. Recently, we have started to administer similar examinations online using the quiz facility in WebCT[TM] and…

Inuwa, Ibrahim Muhammad; Al Rawahy, Maimouna; Taranikanti, Varna; Habbal, Omar

2011-01-01

281

YouTube: An Emerging Tool in Anatomy Education  

ERIC Educational Resources Information Center

|The use of online social networks in medical education can remodel and enhance anatomy teaching and learning; one such network is the video-sharing site YouTube. Limited research in the literature exists on the use of YouTube as a platform for anatomy education. The aim of this study is to assess student's perceptions and patterns of usage of…

Jaffar, Akram Abood

2012-01-01

282

The Gross Anatomy Course: An Analysis of its Importance  

NSDL National Science Digital Library

This article describes a research study investigating medical students' valuation of gross anatomy as an ÃÂimportantÃÂ course. The article describes the qualitative tools used and outcomes found of student's value of gross anatomy lab. Key outcomes include significant differences in developing teamwork skills, stress coping strategies, and empathy.

2010-01-07

283

Anatomy and Mechanics of the Shoulder: Review of Current Concepts  

Microsoft Academic Search

This narrative review is intended to provide hand and upper extremity therapists, who occasionally treat patients with shoulder diagnoses, with several current concepts related to normal shoulder anatomy and function. It is hoped that this review will be useful for 1) appreciating patho-anatomy and pathophysiology, 2) planning treatment approaches, and 3) stimulating research aimed at improved understanding of the shoulder.

Jack Hurov

2009-01-01

284

Measuring Change in Professionalism Attitudes during the Gross Anatomy Course  

ERIC Educational Resources Information Center

|By design or default, anatomy educators are often responsible for introducing students to medical professionalism. Although much has been said about the role of anatomical education, there are no published reports suggesting how to measure change. This study investigated what professionalism attitudes, if any, change during a gross anatomy

Pearson, William G., Jr.; Hoagland, Todd M.

2010-01-01

285

Variation in prostate position relative to adjacent bony anatomy  

Microsoft Academic Search

Purpose: In prostatic cancer, the prostate cannot be discerned from a portal image. Setup information is, therefore, obtained from bony anatomy. To perform high-precision conformal therapy, knowledge about the variation in distance between the prostate and adjacent bony anatomy during an external radiotherapy treatment is mandatory. This report is concerned with that variation.Methods and Materials: Nine patients previously treated interstitially

Vincent G. M. Althof; Carel J. M. Hoekstra; Herman-Jan te Loo

1996-01-01

286

Distinct mouse coronary anatomy and myocardial infarction consequent to ligation  

Microsoft Academic Search

This study describes the coronary anatomy of C57BL\\/6 mice and the functional impact of that anatomy on myocardial infarctions induced by ligation of the left coronary artery. In contrast to humans, a distinct septal coronary artery was observed in all mice arising either from a separate ostium from the right sinus of Valsalva or as a branch of the right

Dinender Kumar; Timothy A. Hacker; Jennifer Buck; Larry F. Whitesell; Eugene H. Kaji; Pamela S. Douglas; Timothy J. Kamp

2005-01-01

287

Comparative Leaf Anatomy of Ficus Linn. Species (Moraceae) from Nigeria  

Microsoft Academic Search

Studies in leaf anatomy of 25 Ficus species in Nigeria have been undertaken to unravel the relationship among the species with a view to providing a set of stable taxonomic characters. Anatomy of the lamina and midrib featured characters that are described in detail for the first time in the Ficus species of Nigeria thus providing the basis for infra-generic

M. A. Sonibare; A. A. Jayeola; A. Egunyomi

2006-01-01

288

Using Multimedia and Web3D to Enhance Anatomy Teaching  

ERIC Educational Resources Information Center

Anatomy teaching is undergoing significant changes due to time constraints, limited availability of cadavers and technological developments in the areas of three-dimensional modelling and computer-assisted learning. This paper gives an overview of methods used to teach anatomy to undergraduate medical students and discusses the educational…

Brenton, Harry; Hernandez, Juan; Bello, Fernando; Strutton, Paul; Purkayastha, Sanjay; Firth, Tony; Darzi, Ara

2007-01-01

289

Perceptions of Anatomy: Critical Components in the Clinical Setting  

ERIC Educational Resources Information Center

|The evolution in undergraduate medical school curricula has significantly impacted anatomy education. This study investigated the perceived role of clinical anatomy and evaluated perceptions of medical students' ability to apply anatomical knowledge in the clinic. The aim of this study was to develop a framework to enhance anatomical educational…

Lazarus, Michelle D.; Chinchilli, Vernon M.; Leong, Shou Ling; Kauffman, Gordon L., Jr.

2012-01-01

290

Anatomy Education in Namibia: Balancing Facility Design and Curriculum Development  

ERIC Educational Resources Information Center

|The anatomy curriculum at Namibia's first, and currently only, medical school is clinically oriented, outcome-based, and includes all of the components of modern anatomical sciences i.e., histology, embryology, neuroanatomy, gross, and clinical anatomy. The design of the facilities and the equipment incorporated into these facilities were…

Wessels, Quenton; Vorster, Willie; Jacobson, Christian

2012-01-01

291

The 2007 Anatomy Ceremony: A Service of Gratitude  

PubMed Central

Yale University medical and PA students, classes of 2010 and 2008 respectively, express their gratitude in a compilation of reflections on learning human anatomy. In coordination with the Section of Anatomy and Experimental Surgery at the School of Medicine, the Yale Journal of Biology and Medicine encourages you to hear the stories of the body as narrated by the student.

2008-01-01

292

The Gross Anatomy Course: An Analysis of Its Importance  

ERIC Educational Resources Information Center

|The gross anatomy dissection course is a cost-intensive piece of undergraduate medical education that students and professionals alike describe as very important within the overall medical curriculum. We sought to understand more explicitly students' valuation of gross anatomy as an "important" course and so developed a quantitative longitudinal…

Bockers, Anja; Jerg-Bretzke, Lucia; Lamp, Christoph; Brinkmann, Anke; Traue, Harald C.; Bockers, Tobias M.

2010-01-01

293

Cranial pneumatic anatomy of Ornithomimus edmontonicus (Ornithomimidae: Theropoda)  

Microsoft Academic Search

Modern archosaurs have extensive pneumatic diverticula originating from paranasal and tympanic sinuses. This complex anatomy is present in many fossil archosaurs, but few descriptions of the complete cranial pneumatic system exist. The cranial pneumatic morphology of birds and non-avian theropods are the best studied, but complete description of this anatomy for an ornithomimid was lacking. We describe the cranial pneumaticity

Rui Tahara; Hans C. E. Larsson

2011-01-01

294

A Minimally Invasive Approach to Undergraduate Anatomy Teaching  

ERIC Educational Resources Information Center

|Anatomy is one of the cornerstones of medical education. Unfortunately, sufficient evidence has accumulated to suggest a worldwide decline in the resources and time allocated to its teaching. Integration of anatomy with clinical medicine has been frequently advocated as the solution to this academic crisis. Consequently, new ways of harnessing…

Gogalniceanu, Petrut; Madani, Hardi; Paraskeva, Paraskevas A.; Darzi, Ara

2008-01-01

295

Controversial snake relationships supported by reproductive anatomy.  

PubMed

Since the advent of molecular character sets in phylogenetic systematics our understanding of the evolutionary history of snakes has changed considerably. In some cases the novel topologies reconstructed from molecular datasets have left researchers puzzled, as no morphological feature seems to support the new relationships found. This is the case for 'Amerophidia'sensu Vidal et al. (2007; Biology of the Boas and Pythons, Eagle Mountain: Eagle Mountain Publishing; Aniliidae+?Tropidophiidae), a grouping of the Red Pipesnakes and Neotropical Dwarf Boas. We contend that in some cases the apparent lack of historical morphological support for the molecular phylogenies is due to our poor understanding of the organisms as a whole, and not the complete lack of morphological support for controversial clades. For example, we found novel evidence from reproductive anatomy that demonstrates a unique association of the oviducts and cloaca in Amerophidia. Whereas in all other female squamates the oviducts communicate directly with the cloaca, the oviducts of Aniliidae and Tropidophiidae communicate with diverticuli of the cloaca. At present this is the only unambiguous synapomorphy for the Amerophidia. We feel that confirmation of controversial molecular relationships will revolve around the investigation of non-traditional morphological characters such as reproductive anatomy. PMID:21323917

Siegel, Dustin S; Miralles, Aurélien; Aldridge, Robert D

2011-01-04

296

The importance of spatial ability and mental models in learning anatomy  

NASA Astrophysics Data System (ADS)

As a foundational course in medical education, gross anatomy serves to orient medical and veterinary students to the complex three-dimensional nature of the structures within the body. Understanding such spatial relationships is both fundamental and crucial for achievement in gross anatomy courses, and is essential for success as a practicing professional. Many things contribute to learning spatial relationships; this project focuses on a few key elements: (1) the type of multimedia resources, particularly computer-aided instructional (CAI) resources, medical students used to study and learn; (2) the influence of spatial ability on medical and veterinary students' gross anatomy grades and their mental models; and (3) how medical and veterinary students think about anatomy and describe the features of their mental models to represent what they know about anatomical structures. The use of computer-aided instruction (CAI) by gross anatomy students at Indiana University School of Medicine (IUSM) was assessed through a questionnaire distributed to the regional centers of the IUSM. Students reported using internet browsing, PowerPoint presentation software, and email on a daily bases to study gross anatomy. This study reveals that first-year medical students at the IUSM make limited use of CAI to study gross anatomy. Such studies emphasize the importance of examining students' use of CAI to study gross anatomy prior to development and integration of electronic media into the curriculum and they may be important in future decisions regarding the development of alternative learning resources. In order to determine how students think about anatomical relationships and describe the features of their mental models, personal interviews were conducted with select students based on students' ROT scores. Five typologies of the characteristics of students' mental models were identified and described: spatial thinking, kinesthetic approach, identification of anatomical structures, problem solving strategies, and study methods. Students with different levels of spatial ability visualize and think about anatomy in qualitatively different ways, which is reflected by the features of their mental models. Low spatial ability students thought about and used two-dimensional images from the textbook. They possessed basic two-dimensional models of anatomical structures; they placed emphasis on diagrams and drawings in their studies; and they re-read anatomical problems many times before answering. High spatial ability students thought fully in three-dimensional and imagined rotation and movement of the structures; they made use of many types of images and text as they studied and solved problems. They possessed elaborate three-dimensional models of anatomical structures which they were able to manipulate to solve problems; and they integrated diagrams, drawings, and written text in their studies. Middle spatial ability students were a mix between both low and high spatial ability students. They imagined two-dimensional images popping out of the flat paper to become more three-dimensional, but still relied on drawings and diagrams. Additionally, high spatial ability students used a higher proportion of anatomical terminology than low spatial ability or middle spatial ability students. This provides additional support to the premise that high spatial students' mental models are a complex mixture of imagistic representations and propositional representations that incorporate correct anatomical terminology. Low spatial ability students focused on the function of structures and ways to group information primarily for the purpose of recall. This supports the theory that low spatial students' mental models will be characterized by more on imagistic representations that are general in nature. (Abstract shortened by UMI.)

Chatterjee, Allison K.

297

Anatomy and Physiology. Module Set I: Introduction to Anatomy and Physiology. Teacher Edition [and] Student Edition. Surgical Technology.  

ERIC Educational Resources Information Center

|This document, which is the first part in a two-part set of modules on anatomy and physiology for future surgical technicians, contains the teacher and student editions of an introduction to anatomy and physiology that consists of modules on the following topics: (1) organization of the human body; (2) biochemistry and microbiology; (3)…

Hilley, Robert

298

Virtual Reality Anatomy: Is It Comparable with Traditional Methods in the Teaching of Human Forearm Musculoskeletal Anatomy?  

ERIC Educational Resources Information Center

|The use of cadavers to teach anatomy is well established, but limitations with this approach have led to the introduction of alternative teaching methods. One such method is the use of three-dimensional virtual reality computer models. An interactive, three-dimensional computer model of human forearm anterior compartment musculoskeletal anatomy

Codd, Anthony M.; Choudhury, Bipasha

2011-01-01

299

Anatomy and Physiology. Module Set I: Introduction to Anatomy and Physiology. Teacher Edition [and] Student Edition. Surgical Technology.  

ERIC Educational Resources Information Center

This document, which is the first part in a two-part set of modules on anatomy and physiology for future surgical technicians, contains the teacher and student editions of an introduction to anatomy and physiology that consists of modules on the following topics: (1) organization of the human body; (2) biochemistry and microbiology; (3) infection,…

Hilley, Robert

300

Anatomy Education in a Changing Medical Curriculum in India: Medical Student Feedback on Duration and Emphasis of Gross Anatomy Teaching  

ERIC Educational Resources Information Center

|Authors report here a survey of medical student feedback on the effectiveness of two different anatomy curricula at Christian Medical College, Vellore, India. Undergraduate medical students seeking the Bachelor in Medicine and Bachelor in Surgery (M.B.B.S.) degrees were divided into two groups by the duration of their respective anatomy

Holla, Sunil Jonathan; Ramachandran, Kalpana; Isaac, Bina; Koshy, Shajan

2009-01-01

301

Integrating Constitutive Gene Expression and Chemoactivity: Mining the NCI60 Anticancer Screen  

PubMed Central

Studies into the genetic origins of tumor cell chemoactivity pose significant challenges to bioinformatic mining efforts. Connections between measures of gene expression and chemoactivity have the potential to identify clinical biomarkers of compound response, cellular pathways important to efficacy and potential toxicities; all vital to anticancer drug development. An investigation has been conducted that jointly explores tumor-cell constitutive NCI60 gene expression profiles and small-molecule NCI60 growth inhibition chemoactivity profiles, viewed from novel applications of self-organizing maps (SOMs) and pathway-centric analyses of gene expressions, to identify subsets of over- and under-expressed pathway genes that discriminate chemo-sensitive and chemo-insensitive tumor cell types. Linear Discriminant Analysis (LDA) is used to quantify the accuracy of discriminating genes to predict tumor cell chemoactivity. LDA results find 15% higher prediction accuracies, using ?30% fewer genes, for pathway-derived discriminating genes when compared to genes derived using conventional gene expression-chemoactivity correlations. The proposed pathway-centric data mining procedure was used to derive discriminating genes for ten well-known compounds. Discriminating genes were further evaluated using gene set enrichment analysis (GSEA) to reveal a cellular genetic landscape, comprised of small numbers of key over and under expressed on- and off-target pathway genes, as important for a compound’s tumor cell chemoactivity. Literature-based validations are provided as support for chemo-important pathways derived from this procedure. Qualitatively similar results are found when using gene expression measurements derived from different microarray platforms. The data used in this analysis is available at http://pubchem.ncbi.nlm.nih.gov/and http://www.ncbi.nlm.nih.gov/projects/geo (GPL96, GSE32474).

Covell, David G.

2012-01-01

302

Functional anatomy of neural circuits regulating fear and extinction.  

PubMed

The memory of fear extinction is context dependent: fear that is suppressed in one context readily renews in another. Understanding of the underlying neuronal circuits is, therefore, of considerable clinical relevance for anxiety disorders. Prefrontal cortical and hippocampal inputs to the amygdala have recently been shown to regulate the retrieval of fear memories, but the cellular organization of these projections remains unclear. By using anterograde tracing in a transgenic rat in which neurons express a dendritically-targeted PSD-95:Venus fusion protein under the control of a c-fos promoter, we found that, during the retrieval of extinction memory, the dominant input to active neurons in the lateral amygdala was from the infralimbic cortex, whereas the retrieval of fear memory was associated with greater hippocampal and prelimbic inputs. This pattern of retrieval-related afferent input was absent in the central nucleus of the amygdala. Our data show functional anatomy of neural circuits regulating fear and extinction, providing a framework for therapeutic manipulations of these circuits. PMID:23027931

Knapska, Ewelina; Macias, Matylda; Mikosz, Marta; Nowak, Aleksandra; Owczarek, Dorota; Wawrzyniak, Marcin; Pieprzyk, Marcelina; Cymerman, Iwona A; Werka, Tomasz; Sheng, Morgan; Maren, Stephen; Jaworski, Jacek; Kaczmarek, Leszek

2012-10-01

303

Integrating anatomy and function for zebrafish circuit analysis.  

PubMed

Due to its transparency, virtually every brain structure of the larval zebrafish is accessible to light-based interrogation of circuit function. Advanced stimulation techniques allow the activation of optogenetic actuators at different resolution levels, and genetically encoded calcium indicators report the activity of a large proportion of neurons in the CNS. Large datasets result and need to be analyzed to identify cells that have specific properties-e.g., activity correlation to sensory stimulation or behavior. Advances in three-dimensional (3D) functional mapping in zebrafish are promising; however, the mere coordinates of implicated neurons are not sufficient. To comprehensively understand circuit function, these functional maps need to be placed into the proper context of morphological features and projection patterns, neurotransmitter phenotypes, and key anatomical landmarks. We discuss the prospect of merging functional and anatomical data in an integrated atlas from the perspective of our work on long-range dopaminergic neuromodulation and the oculomotor system. We propose that such a resource would help researchers to surpass current hurdles in circuit analysis to achieve an integrated understanding of anatomy and function. PMID:23630469

Arrenberg, Aristides B; Driever, Wolfgang

2013-04-23

304

Functional anatomy of neural circuits regulating fear and extinction  

PubMed Central

The memory of fear extinction is context dependent: fear that is suppressed in one context readily renews in another. Understanding of the underlying neuronal circuits is, therefore, of considerable clinical relevance for anxiety disorders. Prefrontal cortical and hippocampal inputs to the amygdala have recently been shown to regulate the retrieval of fear memories, but the cellular organization of these projections remains unclear. By using anterograde tracing in a transgenic rat in which neurons express a dendritically-targeted PSD-95:Venus fusion protein under the control of a c-fos promoter, we found that, during the retrieval of extinction memory, the dominant input to active neurons in the lateral amygdala was from the infralimbic cortex, whereas the retrieval of fear memory was associated with greater hippocampal and prelimbic inputs. This pattern of retrieval-related afferent input was absent in the central nucleus of the amygdala. Our data show functional anatomy of neural circuits regulating fear and extinction, providing a framework for therapeutic manipulations of these circuits.

Knapska, Ewelina; Macias, Matylda; Mikosz, Marta; Nowak, Aleksandra; Owczarek, Dorota; Wawrzyniak, Marcin; Pieprzyk, Marcelina; Cymerman, Iwona A.; Werka, Tomasz; Sheng, Morgan; Maren, Stephen; Jaworski, Jacek; Kaczmarek, Leszek

2012-01-01

305

Terminology — CBIIT: Welcome to the NCI Center for Biomedical Informatics and Information Technology  

Cancer.gov

Enterprise Vocabulary Services (EVS) works with NCI and extramural partners to develop, license, and publish terminology; to support software applications; and to promote harmonization and shared standards. EVS provides the foundational layer for NCI's informatics infrastructure, and participates in federal and international standards efforts. The EVS Wiki provides details on EVS resources, applications, and services.

306

About CBIIT — CBIIT: Welcome to the NCI Center for Biomedical Informatics and Information Technology  

Cancer.gov

NCI created CBIIT to lead the coordination, development, and deployment of enterprise-wide digital capabilities (including biomedical informatics, scientific-management information systems, and computing resources) in support of the Institute's initiatives. Through CBIIT, NCI is helping to speed scientific discovery and facilitate translational research by using IT and informatics to address complex research challenges.

307

NCI Thesaurus: A semantic model integrating cancer-related clinical and molecular information  

Microsoft Academic Search

Over the last 8 years, the National Cancer Institute (NCI) has launched a major effort to integrate molecular and clinical cancer-related information within a unified biomedical informatics framework, with controlled terminology as its foundational layer. The NCI Thesaurus is the reference terminology underpinning these efforts. It is designed to meet the growing need for accurate, comprehensive, and shared terminology, covering

Nicholas Sioutos; Sherri De Coronado; Margaret W. Haber; Frank W. Hartel; Wen-ling Shaiu; Lawrence W. Wright

2007-01-01

308

SPIE Medical Imaging Conference NCI Lung Image Database Consortium (LIDC): Open meeting, February 15  

Cancer.gov

NCI Lung Image Database Consortium (LIDC): Open Meeting San Diego Room · Sunday, 5:45 to 7:45 pm Academic Chairs: Samuel G. Armato, III, Univ. of Chicago; Geoffrey McLennan, Univ. of Iowa NCI Program staff: Larry Clarke and Barbara Croft, Cancer

309

NCI Director's Address, Annual Meeting of the American Society for Clinical Oncology, June 2011  

Cancer.gov

Harold Varmus delivered the NCI Director’s Address at the annual meeting of the American Society for Clinical Oncology where he talked about the unprecedented opportunities to accelerate progress against cancer and NCI’s plans to move research forward even as it deals with budgetary challenges.

310

[Anatomy of the pelvic lymphatic system].  

PubMed

The lymphatic system of the pelvis collects the lymph of the genital and urinary organs and of the digestive tract. It is formed by lymphatic nodes and vessels situated inside the conjunctive tissue, near the organs (visceral lymphatic nodes) but especially along the external, internal and common iliac vessels (iliac lymphatic nodes). These nodes receive afferent vessels issued from the different pelvic organs. From the iliac lymphnodes arise efferent vessels running towards lymphatic collectors, situated above them, and which end in the lymphatic lombar duct. The lymphatic pathways represent the preferential way of scattering of cancerous cells. Therefore, the knowledge of the anatomy, of the situation and of the draining of the nodes is of the utmost importance in the evaluation of a cancer of a pelvic organ. PMID:24007954

Wolfram-Gabel, R

2013-09-03

311

The anatomy of the lateral canthal tendon.  

PubMed

This report documents the anatomy of the lateral canthus using gross dissection, histologic examination, computed tomography, magnetic resonance imaging, and clinical measurement. Lateral canthal dissections of 16 cadaver orbits demonstrated a well-defined attachment of the tarsal plates to the orbital rim, averaging 10.6 mm in length and 10.2 mm in width at their insertion on Whitnall's tubercle, 1.5 mm behind the orbital rim and 9.7 mm inferior to the frontozygomatic suture. Histologic examination showed a band of dense fibrous tissue attached to the tarsal plates, with intermingled muscle fibers from the pretarsal orbicularis oculi muscle. A small pocket of fat was identified posterior to the orbital septum and anterior to the lateral canthal tendon. Clinical measurements of normal adults revealed 2 mm of lateral movement of the canthal angle during abduction, apparently caused by posterior fibrous attachments to the check ligament of the lateral rectus muscle. PMID:3566607

Gioia, V M; Linberg, J V; McCormick, S A

1987-04-01

312

Anatomy of a Lactococcal Phage Tail†  

PubMed Central

Bacteriophages of the Siphoviridae family utilize a long noncontractile tail to recognize, adsorb to, and inject DNA into their bacterial host. The tail anatomy of the archetypal Siphoviridae ? has been well studied, in contrast to phages infecting gram-positive bacteria. This report outlines a detailed anatomical description of a typical member of the Siphoviridae infecting a gram-positive bacterium. The tail superstructure of the lactococcal phage Tuc2009 was investigated using N-terminal protein sequencing, Western blotting, and immunogold transmission electron microscopy, allowing a tangible path to be followed from gene sequence through encoded protein to specific architectural structures on the Tuc2009 virion. This phage displays a striking parity with ? with respect to tail structure, which reenforced a model proposed for Tuc2009 tail architecture. Furthermore, comparisons with ? and other lactococcal phages allowed the specification of a number of genetic submodules likely to encode specific tail structures.

Mc Grath, Stephen; Neve, Horst; Seegers, Jos F. M. L.; Eijlander, Robyn; Vegge, Christina S.; Br?ndsted, Lone; Heller, Knut J.; Fitzgerald, Gerald F.; Vogensen, Finn K.; van Sinderen, Douwe

2006-01-01

313

The clinical anatomy of the coronary arteries.  

PubMed

There are a manifold number of variations and anomalies of the origin and course of coronary arteries described in the literature. The incidence of such variations in the general population is reported to range between 0.3 and 1.6 %. Although uncommon, they may be benign or produce symptoms ranging from mild dyspnea to sudden cardiac death, and have been associated with an increased risk of accelerated atherosclerosis and perfusion defects. Thus, in order to effectively utilize the increasing number of therapeutic options available for treating coronary artery diseases, an appreciation of the likely normal and variable arrangements of the coronary arteries is essential. This review will describe the normal anatomy of the coronary arteries as well as the common variations with potential clinical effects. PMID:23423864

Loukas, Marios; Sharma, Amit; Blaak, Christa; Sorenson, Edward; Mian, Asma

2013-02-20

314

MR imaging of normal hip anatomy.  

PubMed

Understanding normal anatomy of the hip is important for diagnosing its pathology. MR arthrography is more sensitive for the detection of intra-articular pathology than noncontrast MR imaging. Important elements of the osseous structures on MR imaging include the alignment and the marrow. Acetabular ossicles may be present. Normal variations involving the cartilage include the supra-acetabular fossa and the stellate lesion. Important muscles of the hip are the sartorius, rectus femoris, iliopsoas, gluteus minimus and medius, adductors, and hamstrings. The iliofemoral, ischiofemoral, and pubofemoral ligaments represent thickenings of the joint capsule that reinforce and stabilize the hip joint. Normal variations in the labrum include labral sulcus and absent labrum. The largest nerves in the hip and thigh are the sciatic nerve, the femoral nerve, and the obturator nerve. PMID:23168179

Chang, Connie Y; Huang, Ambrose J

2012-10-10

315

The anatomy of the hip abductor muscles.  

PubMed

The anatomy of the hip abductors has not been comprehensively examined, yet is important to understanding function and pathology in the gluteal region. For example, pathology of the hip abductor muscle-tendon complexes can cause greater trochanteric pain syndrome, and may be associated with gluteal atrophy and fatty infiltration. The purpose of this study was to investigate the detailed morphology of gluteus medius (GMed), gluteus minimus (GMin), and tensor fascia lata (TFL), and determine whether the muscles comprised anatomical compartments. The gluteal region from 12 cadavers was dissected and data collected on attachment sites, volume, fascicular and tendinous anatomy, and innervation. Three sites of GMed origin were identified (gluteal fossa, gluteal aponeurosis, and posteroinferior edge of the iliac crest) and the distal tendon had lateral and posterior parts. GMed was the largest in volume (27.6?±?11.6 cm(3) ; GMin 14.1?±?11.1 cm(3) ; TFL 1.8?±?0.8 cm(3) ). Fascicles of GMin originated from the gluteal fossa, inserting onto the deep surface of its distal tendon and the hip joint capsule. TFL was encapsulated in the fascia lata, having no bony attachment. Primary innervation patterns varied for GMed, with three or four branches supplying different regions of muscle. Distinct secondary nerve branches entered four regions of GMin; no differential innervation was observed for TFL. On the basis of architectural parameters and innervation, GMed, and GMin each comprise of four compartments but TFL is a homogenous muscle. It is anticipated that these data will be useful for future clinical and functional studies of the hip abductors. Clin. Anat. 00:000-000, 2013. © 2013 Wiley Periodicals, Inc. PMID:23625344

Flack, N A M S; Nicholson, H D; Woodley, S J

2013-04-27

316

The Beauty of Anatomy: Visual Displays and Surgical Education in Early-Nineteenth-Century London  

Microsoft Academic Search

The early-nineteenth-century artist, anatomist, and teacher Sir Charles Bell saw anatomy and art as closely related subjects. He taught anatomy to artists and surgeons, illustrated his own anatomical texts, and wrote a treatise on the use of anatomy in art. The author explores the connections among visual displays representing human anatomy, aesthetics, and pedagogical practices for Bell and a particular

Carin Berkowitz

2011-01-01

317

Spatial Abilities in an Elective Course of Applied Anatomy after a Problem-Based Learning Curriculum  

ERIC Educational Resources Information Center

|A concern on the level of anatomy knowledge reached after a problem-based learning curriculum has been documented in the literature. Spatial anatomy, arguably the highest level in anatomy knowledge, has been related to spatial abilities. Our first objective was to test the hypothesis that residents are interested in a course of applied anatomy

Langlois, Jean; Wells, George A.; Lecourtois, Marc; Bergeron, Germain; Yetisir, Elizabeth; Martin, Marcel

2009-01-01

318

The Breast Cancer Detection Demonstration Project (BCDDP) Follow-up Study  

Cancer.gov

Study subjects were participants in the Breast Cancer Detection Demonstration Project (BCDDP), a breast cancer screening program conducted between 1973 and 1980. Sponsored by the American Cancer Society and the NCI, the BCDDP provided up to five annual breast examinations to 283,222 women at 29 screening centers in 27 cities throughout the United States.

319

Case Study: Bad Fish: Human Anatomy and Physiology Edition  

NSDL National Science Digital Library

This is a case study for high school and undergraduate students in anatomy, physiology, and/or anatomy and physiology courses. In particular this case study explores anatomy and physiology associated with the nervous system. Users of the National Center for Case Study Teaching in Science will be required to register (free) to gain access to the answer key (and must be of teaching status to receive the key). Included in the resource are the case overview, objectives, case study, teaching notes and answer key.

James Hewlett (Finger Lakes Community College Science and Technology)

2003-04-13

320

Michelangelo: anatomy and its implication in his art.  

PubMed

Michelangelo's major interest was the Life of the Soul as expressed in the beautiful structure and movement of the human body, which he often called the "mortal veil" of the divine intentions. This study ascertains Michelangelo's interest in and acquisition of the knowledge of human anatomy, the use of small anatomical models to crystallize his concepts into reality and the application of anatomy to his art. Relatively little is known of this interaction between anatomy and art in Michelangelo's life and work. PMID:20027756

Hilloowala, Rumy

2009-06-01

321

NCI Funded Research Portfolio - ZIASC010357 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

322

NCI Funded Research Portfolio - ZIABC011005 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

323

NCI Funded Research Portfolio - ZICSC009431 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

324

NCI Funded Research Portfolio - ZIABC005522 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

325

NCI Funded Research Portfolio - ZIASC006387 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

326

NCI Funded Research Portfolio - ZIASC000550 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

327

NCI Funded Research Portfolio - ZIABC010308 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

328

NCI Funded Research Portfolio - ZIABC011351 Detail  

Cancer.gov

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329

NCI Funded Research Portfolio - ZIASC010376 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

330

NCI Funded Research Portfolio - ZIASC003657 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

331

NCI Funded Research Portfolio - ZIABC010763 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

332

NCI Funded Research Portfolio - ZIDBC010694 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

333

NCI Funded Research Portfolio - ZIABC010652 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

334

NCI Funded Research Portfolio - PUR2765678 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

335

NCI Funded Research Portfolio - PUR2682003 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

336

NCI Funded Research Portfolio - ZIABC011064 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

337

NCI Funded Research Portfolio - ZIABC010326 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

338

NCI Funded Research Portfolio - N01006663001 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

339

NCI Funded Research Portfolio - ZIABC011062 Detail  

Cancer.gov

Skip to content Your source for National Cancer Institute funded research grants, contract awards, and intramural research projects. More Home Advanced Search Funding Statistics About NFRP Contact Us Related Links Help Viewing Project « Back to results

340

NCI Funded Research Portfolio - ZIABC011470 Detail  

Cancer.gov

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341

Duplex ultrasound investigation of the veins in chronic venous disease of the lower limbs-UIP consensus document. Part II. Anatomy  

Microsoft Academic Search

Objectives. Duplex ultrasound investigation has become the reference standard in assessing the morphology and haemodynamics of the lower limb veins. The project described in this paper was an initiative of the Union Internationale de Phlebologie (UIP), The aim was to obtain a consensus of international experts on the methodology to be used for assessment of anatomy of superficial and perforating

A. Cavezzi; N. Labropoulos; H. Partsch; S. Ricci; A. Caggiati; K. Myers; A. Nicolaides; P Coleridge-Smith

2007-01-01

342

NCI Funded Research Portfolio - Z01 BC 010569 Detail  

Cancer.gov

A central mission of the Center for Cancer Research (CCR), National Cancer Institute (NCI) is the development and delivery of novel cancer treatment strategies for cancer patients. A significant hurdle in the translation of information from the laboratory to the clinic is the availability of appropriate preclinical cancer models. Through a number of new initiatives the CCR has created an essential infrastructure to facilitate the translational research process.

343

NCI Funded Research Portfolio - ZIC SC 009431 Detail  

Cancer.gov

Accurate histologic characterization of pediatric tumors is necessary for the enrolment of patients in the clinical trials of the Pediatric Oncology Branch (POB) at the NCI. The diagnosis of the solid pediatric tumors is often difficult and requires a combination of diagnostic techniques. Most pediatric solid tumors are characterized by consistent chromosomal translocations which result in the fusion of genes and subsequent formation of novel chimeric genes.

344

NCI Funded Research Portfolio - Z01 SC 009431 Detail  

Cancer.gov

Accurate histologic characterization of pediatric tumors is necessary for the enrolment of patients in the clinical trials of the Pediatric Oncology Branch (POB) at the NCI. The diagnosis of the solid pediatric tumors is often difficult and requires a combination of diagnostic techniques. Most pediatric solid tumors are characterized by consistent chromosomal translocations which result in the fusion of genes and subsequent formation of novel chimeric genes.

345

Division of Cancer Epidemiology and Genetics (DCEG), NCI, NIH  

Cancer.gov

The Division of Cancer Epidemiology and Genetics (DCEG) is a research program of the National Cancer Institute (NCI), one of the National Institutes of Health (NIH). The Division is the world’s most comprehensive cancer epidemiology research group. Its renowned epidemiologists, geneticists, and biostatisticians conduct population and multidisciplinary research to discover the genetic and environmental determinants of cancer and new approaches to cancer prevention. The Division’s research impacts public health policy in the United States and around the world.

346

``Thatcher's Ghost'': Confirmation of the ? Cygnids (NCY, IAU #409)  

NASA Astrophysics Data System (ADS)

A ghostly image of meteor radiants appeared in the CAMS data north-east of the Lyrids on April 22, 2012. The diffuse shower is identified as the ? Cygnids (NCY). It is weakly active from April 17 to 26, and likely related to the April ? Cygnids (ARC), active in the area after April 27. The ? Cygnids may have been in outburst in 2012, because this shower was not as evident in the 2007-2011 SonotaCo data.

Jenniskens, Peter; Haberman, Bob

2013-06-01

347

NCI Funded Research Portfolio - Z01 SC 000853 Detail  

Cancer.gov

The Section of Surgical Pathology provides all diagnostic services to support the NCI, the Clinical Center and other NIH Institutes. Approximately 6000 specimens were processed and studied last year.This human tissue material is used in a variety of applied research studies in collaboration with associated clinicians and under IRB approved protocols.We train 9 residents in anatomic pathology as well as many visiting fellows, medical students from other institutions and CERTAS.

348

NCI Funded Research Portfolio - ZIE SC 000853 Detail  

Cancer.gov

The Translational Surgical Pathology section provides diagnostic services to support the NCI, the NIH Clinical Center, other NIH Institutes, and the Urologic Oncology Branch, CCR. Many specimens are processed and studied every year. This human tissue material is used in a variety of applied research studies in collaboration with associated clinicians and under Institutional Review Board-approved protocols. We train 9 residents in anatomic pathology as well as many visiting fellows, medical students from other institutions, and CRTA fellows.

349

Patterns in food use and compliance with NCI dietary guidelines  

Microsoft Academic Search

We developed multidimensional measures of diet by identifying seven gender?specific patterns among 1,475 male and 780 female subjects selected as neighborhood controls in a case?control study of cancer at various sites. The purpose of this study was to examine these patterns for compliance with the National Cancer Institute (NCI) Dietary Guidelines. Diets were scored and each subject assigned fertile ranks

D. Elizabeth Randall; James R. Marshall; John Brasure; Saxon Graham

1991-01-01

350

NCI Funded Research Portfolio - ZIA BC 011019 Detail  

Cancer.gov

Eighteen paraffin-embedded tissue blocks obtained from autopsy specimens have been collected from patients treated at NCI and outside institutions. These are currently undergoing pathology confirmation and review. A representative area of tumor will be collected from the block. DNA will be extracted from the core with standard procedures. Tumor DNA will be processed for high resolution comparative genomic hybridization. Regions of copy number change will be identified using circular binary segmentation of the array data.

351

NCI Funded Research Portfolio - Z01 BC 011019 Detail  

Cancer.gov

Fourteen paraffin-embedded tissue blocks obtained from autopsy specimens have been collected from patients treated at NCI and two other institutions. These are currently undergoing pathology confirmation and review. A representative area of tumor will be collected from the block. DNA will be extracted from the core with standard procedures. Tumor DNA will be processed for high resolution comparative genomic hybridization. Regions of copy number change will be identified using circular binary segmentation of the array data.

352

NCI Community Cancer Centers Program - Related Programs - Cancer Information Service  

Cancer.gov

The National Cancer Institute�s (NCI) Cancer Information Service (CIS) educates the public about cancer prevention, risk factors, symptoms, diagnosis, treatment, and research . CIS information specialists provide the latest, most accurate information about cancer by telephone, TTY, instant messaging, and e-mail and operates the NCI�s Smoking Quitline. Through its Partnership Program, the CIS works with established national, regional, and state organizations to reach those most in need of cancer information.

353

NCI Funded Research Portfolio - ZIA CP010177-01052 Detail  

Cancer.gov

This clinical trial is to evaluate the prophylactic efficacy of two HPV 16 VLP-based vaccines developed at NCI. Participants will be randomized into one of three arms (two experimental arms and a placebo arm). The vaccine will be administered without adjuvant, since early trials suggested increased ractogenicity without parallel increases in immunogenicity among volunteers vaccinated with VLP plus adjuvant. Three doses will be administered intramuscularly at entry, one month, and six months.

354

Bacteria detected on surfaces of formalin fixed anatomy cadavers.  

PubMed

The purpose of this study is to determine if anatomy cadavers fixed in a formalin solution are a possible source of introduction of microorganisms into the anatomy laboratory. Routinely preserved cadavers were sampled for microbiological contaminates prior to examination and dissection by anatomy students. Regions sampled include the axilla, oral/nasal cavity, and inguinal/perineal region. Using conventional bacteriologic culture and identification methods our research group was able to successfully recover and identify a variety of organisms from all cadavers and in all regions tested. The results indicate that cadavers processed with 10% buffered formalin have viable organisms on their surfaces that can be a source of contamination of laboratory equipment and clothing. Given the diversity of bacterial species cultured, preserved cadavers used for anatomy education as well as research must be considered a possible source for dissemination of bacterial organisms. This study underscores the importance of standard infection control protocols. PMID:23898574

Tabaac, Burton; Goldberg, Geoffrey; Alvarez, Lia; Amin, Molly; Shupe-Ricksecker, Kathleen; Gomez, Fernando

2013-01-01

355

Shoulder ultrasound imaging-integrating anatomy, biomechanics and disease processes  

Microsoft Academic Search

This article brings together the anatomy, biomechanics and the imaging of shoulder disease using ultrasound to enable a better understanding of the strengths and weaknesses of ultrasound when imaging the shoulder.

Gina M. Allen

2008-01-01

356

Implementing Adaptive Technology and Supplemental Curriculum for Anatomy and Physiology.  

National Technical Information Service (NTIS)

This document is focused on describing how, technically, implementing adaptive technology and supplemental curriculum for Anatomy and Physiology is developed from a functional use aspect including Functionality Use Case Scenarios, Technical Architecture O...

B. Sahota S. Nagarathnam T. Mathur

2002-01-01

357

Standardized review of atrial anatomy for cardiac electrophysiologists.  

PubMed

Catheter ablation of cardiac arrhythmias has rapidly evolved from a highly experimental procedure to a standard form of therapy for various tachyarrhythmias. The advances in this field have included, first, the development of techniques of catheter ablation that often requires the precise destruction of minute amounts of arrhythmogenic tissues and, second, techniques of resynchronization therapy that require pacing different parts of the ventricles. A detailed prepocedural knowledge of cardiac anatomy can improve the safety of the procedure and its rate success. It helps the electrophysiologist to choose the appropiate region for ablation, shortening the procedural time. The atrial anatomy structures are usually localized before ablation by different imaging techniques such as fluoroscopy, electroanatomic mapping, intracardiac echocardiography or multidetector computed tomography. In this review, we describe the normal anatomy of the atria, highlighting the landmarks of interest to intervencional cardiologist, stressing their relationship to other structures. This article is part of a JCTR special issue on Cardiac Anatomy. PMID:23389853

Sánchez-Quintana, Damián; Pizarro, Gonzalo; López-Mínguez, José Ramón; Ho, Siew Yen; Cabrera, José Angel

2013-02-07

358

Evaluation of anatomy comic strips for further production and applications  

PubMed Central

The corresponding author of the study has been sketching comic strips to explain anatomy in a humorous manner. All the anatomy comic strips, including those in Korean (650 episodes) and English (451 episodes), can be viewed on the homepage (http://anatomy.co.kr). Such comic strips were created with the aim of assisting medical students. However, their impact was unknown, and therefore, we surveyed the students' responses. We noted that anatomy grades were better in the students who read the comic strips. The comics helped the trainees chat with individuals with and without a medical background. The authors also considered comments on the problems with the comic strips and attempted to find solutions. The episodes are being currently used and further produced for educational purposes. To support this effort, the readers' valuable opinions will be continuously collected and assessed.

Shin, Dong Sun; Kim, Dae Hyun; Park, Jin Seo; Jang, Hae Gwon

2013-01-01

359

Comparative Anatomy of the Audio-Vestibular Organ.  

National Technical Information Service (NTIS)

The comparative anatomy of the inner ear and middle ear regions of vertebrates is presented based on research during the eighteenth, nineteenth and twentieth centuries up to 1934 by researchers all over the world. Over 400 references are cited. (Author)

H. M. Deburlet

1975-01-01

360

Gender differences in glenoid anatomy: an anatomic study  

Microsoft Academic Search

Gender differences in glenoid anatomy have not been well studied in the current literature. Previous literature demonstrates\\u000a a mismatch between glenoid anatomy and glenoid implants for shoulder replacements. This may have clinical implications in\\u000a that glenoid loosening after shoulder arthroplasty has been cited as a frequent cause of poor performance of shoulder implants,\\u000a and perhaps the most common indication for

Andrea Merrill; Kara Guzman; Suzanne L. Miller

2009-01-01

361

The Teleost Anatomy Ontology: Anatomical Representation for the Genomics Age  

PubMed Central

The rich knowledge of morphological variation among organisms reported in the systematic literature has remained in free-text format, impractical for use in large-scale synthetic phylogenetic work. This noncomputable format has also precluded linkage to the large knowledgebase of genomic, genetic, developmental, and phenotype data in model organism databases. We have undertaken an effort to prototype a curated, ontology-based evolutionary morphology database that maps to these genetic databases (http://kb.phenoscape.org) to facilitate investigation into the mechanistic basis and evolution of phenotypic diversity. Among the first requirements in establishing this database was the development of a multispecies anatomy ontology with the goal of capturing anatomical data in a systematic and computable manner. An ontology is a formal representation of a set of concepts with defined relationships between those concepts. Multispecies anatomy ontologies in particular are an efficient way to represent the diversity of morphological structures in a clade of organisms, but they present challenges in their development relative to single-species anatomy ontologies. Here, we describe the Teleost Anatomy Ontology (TAO), a multispecies anatomy ontology for teleost fishes derived from the Zebrafish Anatomical Ontology (ZFA) for the purpose of annotating varying morphological features across species. To facilitate interoperability with other anatomy ontologies, TAO uses the Common Anatomy Reference Ontology as a template for its upper level nodes, and TAO and ZFA are synchronized, with zebrafish terms specified as subtypes of teleost terms. We found that the details of ontology architecture have ramifications for querying, and we present general challenges in developing a multispecies anatomy ontology, including refinement of definitions, taxon-specific relationships among terms, and representation of taxonomically variable developmental pathways.

Dahdul, Wasila M.; Lundberg, John G.; Midford, Peter E.; Balhoff, James P.; Lapp, Hilmar; Vision, Todd J.; Haendel, Melissa A.; Westerfield, Monte; Mabee, Paula M.

2010-01-01

362

Cytogenetic characterization of NCI-H69 and NCI-H69AR small cell lung cancer cell lines by spectral karyotyping  

Microsoft Academic Search

Small cell lung cancer (SCLC) shows an excellent sensitivity to chemotherapy, but commonly develops resistance after a few months. An early identification of a genomic marker in drug discovery may help to select patients who would respond to treatment in clinical trials. Herein, we characterized the parental NCI-H69 (sensitive) and NCI-H69AR (anthracycline-resistant) cell lines by G-banding and spectral karyotyping (SKY).

Marta Salido; Edurne Arriola; Alma Carracedo; Israel Cañadas; Ana Rovira; Blanca Espinet; Federico Rojo; Montse Arumi; Sergi Serrano; Joan Albanell; Francesc Sole

2009-01-01

363

NCI Funded Research Portfolio - ZIASC010373 Detail  

Cancer.gov

The goal of this project is to study the interaction of radiotherapy and molecularly targeted agents. This project focuses on expanding drugs that show synergy in vitro to the in vivo setting, with the goal of translation to the clinic. This is a translational project. We begin in the laboratory testing drugs in combination with radiotherapy in vitro. Once in vitro sensitivity is comfirmed then we do in vivo work with sc or ic animal models.

364

Formaldehyde Exposures in a University Anatomy Laboratory  

NASA Astrophysics Data System (ADS)

Air sampling studies were conducted within a university anatomical laboratory during the embalmment of a cadaver in order to determine if dangerous concentrations of formaldehyde existed. Three air sampling studies were conducted in the anatomical laboratory on three separate days that a cadaver was being embalmed. Samples were collected and analyzed using the Occupational Safety and Health Administration (OSHA) Sampling and Analytical Methods: Method 52. Each air sampling study sampled for short term exposure limit (STEL) and time weighted mean (TWA) breathing zone formaldehyde concentrations as well as area TWA formaldehyde concentrations. A personal aldehyde monitor was also used in each air sampling study to sample for breathing zone formaldehyde concentrations. Measured TWA mean exposures to formaldehyde ranged from 0.15--1.3 parts per million (ppm), STEL formaldehyde exposures ranged from 0.019--0.64 ppm, and eight-hour TWAs ranged from 0.03 to 3.6 ppm. All 8-hour TWA formaldehyde concentrations sampled in the anatomy laboratory during an embalmment were less than the permissible exposure limit (PEL) required by OSHA.

Winkler, Kyle William

365

The functional anatomy of suggested limb paralysis.  

PubMed

Suggestions of limb paralysis in highly hypnotically suggestible subjects have been employed to successfully model conversion disorders, revealing similar patterns of brain activation associated with attempted movement of the affected limb. However, previous studies differ with regard to the executive regions involved during involuntary inhibition of the affected limb. This difference may have arisen as previous studies did not control for differences in hypnosis depth between conditions and/or include subjective measures to explore the experience of suggested paralysis. In the current study we employed functional magnetic resonance imaging (fMRI) to examine the functional anatomy of left and right upper limb movements in eight healthy subjects selected for high hypnotic suggestibility during (i) hypnosis (NORMAL) and (ii) attempted movement following additional left upper limb paralysis suggestions (PARALYSIS). Contrast of left upper limb motor function during NORMAL relative to PARALYSIS conditions revealed greater activation of contralateral M1/S1 and ipsilateral cerebellum, consistent with the engagement of these regions in the completion of movements. By contrast, two significant observations were noted in PARALYSIS relative to NORMAL conditions. In conjunction with reports of attempts to move the paralysed limb, greater supplementary motor area (SMA) activation was observed, a finding consistent with the role of SMA in motor intention and planning. The anterior cingulate cortex (ACC, BA 24) was also significantly more active in PARALYSIS relative to NORMAL conditions - suggesting that ACC (BA 24) may be implicated in involuntary, as well as voluntary inhibition of prepotent motor responses. PMID:23351848

Deeley, Quinton; Oakley, David A; Toone, Brian; Bell, Vaughan; Walsh, Eamonn; Marquand, Andre F; Giampietro, Vincent; Brammer, Michael J; Williams, Steven C R; Mehta, Mitul A; Halligan, Peter W

2012-12-21

366

Comparative anatomy and histology of xenarthran osteoderms.  

PubMed

Reconstruction of soft tissues in fossil vertebrates is an enduring challenge for paleontologists. Because inferences must be based on evidence from hard tissues (typically bones or teeth), even the most complete fossils provide only limited information about certain organ systems. Osteoderms ("dermal armor") are integumentary bones with high fossilization potential that hold information about the anatomy of the skin in many extant and fossil amniotes. Their importance for functional morphology and phylogenetic research has recently been recognized, but studies have focused largely upon reptiles, in which osteoderms are most common. Among mammals, osteoderms occur only in members of the clade Xenarthra, which includes armadillos and their extinct relatives: glyptodonts, pampatheres, and, more distantly, ground sloths. Here, I present new information on the comparative morphology and histology of osteoderms and their associated soft tissues in 11 extant and fossil xenarthrans. Extinct mylodontid sloths possessed simple, isolated ossicles, the presence of which is likely plesiomorphic for Xenarthra. More highly derived osteoderms of glyptodonts, pampatheres, and armadillos feature complex articulations and surface ornamentation. Osteoderms of modern armadillos are physically associated with a variety of soft tissues, including nerve, muscle, gland, and connective tissue. In some cases, similar osteological features may be caused by two or more different tissue types, rendering soft-tissue inferences for fossil osteoderms equivocal. Certain osteological structures, however, are consistently associated with specific soft-tissue complexes and therefore represent a relatively robust foundation upon which to base soft-tissue reconstructions of extinct xenarthrans. PMID:17103396

Hill, Robert V

2006-12-01

367

Monte Carlo dose mapping on deforming anatomy  

PubMed Central

This paper proposes a Monte Carlo-based energy and mass congruent mapping (EMCM) method to calculate the dose on deforming anatomy. Different from dose interpolation methods, EMCM separately maps each voxel’s deposited energy and mass from a source image to a reference image with a displacement vector field (DVF) generated by deformable image registration (DIR). EMCM was compared with other dose mapping methods: energy-based dose interpolation (EBDI) and trilinear dose interpolation (TDI). These methods were implemented in EGSnrc/DOSXYZnrc, validated using a numerical deformable phantom and compared for clinical CT images. On the numerical phantom with an analytically invertible deformation map, EMCM mapped the dose exactly the same as its analytic solution, while EBDI and TDI had average dose errors of 2.5% and 6.0%. For a lung patient’s IMRT treatment plan, EBDI and TDI differed from EMCM by 1.96% and 7.3% in the lung patient’s entire dose region, respectively. As a 4D Monte Carlo dose calculation technique, EMCM is accurate and its speed is comparable to 3D Monte Carlo simulation. This method may serve as a valuable tool for accurate dose accumulation as well as for 4D dosimetry QA.

Zhong, Hualiang; Siebers, Jeffrey V

2010-01-01

368

Functional implications of felid forelimb anatomy.  

PubMed

The elbow and wrist anatomy of 17 felid species were studied and compared with that of other representative mammaliam carnivores. Based on the shape and position of the olecranon fossa, it was determined that for felids the forelimb cannot travel in a "pendulum-like" motion during locomotion, but must travel through an arch away from the parasagittal plane of the body. For the anterior limb, the degree of deviation from the parasagittal plane was correlated with habitat preference. In this regard, those felids that are exclusive forest dwellers (found exclusively in high, densely structured habitats) had the greatest angle of inclination of the olecranon fossa. In addition, these, species had a large lateral olecranon tuberosity for the attachment of the lateral head of the triceps muscle. For those felids that inhabit more open terrain (low-structured habitat), the olecranon fossa was less inclined, the medical olecranon tuberosity relatively large, and the medial head of the triceps was significantly heavier than those of the forest felids. Both the wrist and elbow joints exhibited a large degree of mobility which was reflective of the claw-equipped forelimb being used as a hunting weapon. PMID:685643

Gonyea, W J

1978-01-01

369

Anatomy meets architecture: designing new laboratories for new anatomists.  

PubMed

General notions of architecture are familiar to anatomists, and they frequently use the word in describing the functional structures of cells, tissues, and whole organisms. Beyond concepts relating to orderly structure, anatomists infrequently encounter the profession of architecture and practicing architects. Significantly, anatomists can work with architects in the design and building of laboratories and classrooms, efforts that can have sustained effects on the practice of anatomy. In this paper, we consider cooperative interactions between anatomists and architects in designing new laboratories that accommodate educational innovations and increasingly valuable dissection resources. We begin by introducing architecture and architects in their roles in design and building. We next consider essential features and technologies for new laboratories that support a combination of classical dissection, prosection, models, and computer-based information. Different working conditions are reviewed for designing renovations of existing facilities, long-term planning for new, same-institution buildings, and extramural planning and construction for new medical schools. Whatever the project, anatomists work with architects in repeated interactive planning meetings that arrive at working laboratory designs by a process similar to successive approximation. In consulting on designs for extramural institutions, anatomists must balance client administration and faculty needs with objective oversight of practice-side design features, constraints, and capacity for innovative uses with new curricula. Architects are the key agents in producing laboratories designed for flexible and innovative anatomical education, although client-favored models for Internet-based technology can limit future use of cadavers in multiyear teaching of medical and health sciences students. PMID:17109425

Trelease, Robert B

2006-11-01

370

Content-specific auditing of a large scale anatomy ontology.  

PubMed

Biomedical ontologies are envisioned to be usable in a range of research and clinical applications. The requirements for such uses include formal consistency, adequacy of coverage, and possibly other domain specific constraints. In this report we describe a case study that illustrates how application specific requirements may be used to identify modeling problems as well as data entry errors in ontology building and evolution. We have begun a project to use the UW Foundational Model of Anatomy (FMA) in a clinical application in radiation therapy planning. This application focuses mainly (but not exclusively) on the representation of the lymphatic system in the FMA, in order to predict the spread of tumor cells to regional metastatic sites. This application requires that the downstream relations associated with lymphatic system components must only be to other lymphatic chains or vessels, must be at the appropriate level of granularity, and that every path through the lymphatic system must terminate at one of the two well known trunks of the lymphatic system. It is possible through a programmable query interface to the FMA to write small programs that systematically audit the FMA for compliance with these constraints. We report on the design of some of these programs, and the results we obtained by applying them to the lymphatic system. The algorithms and approach are generalizable to other network organ systems in the FMA such as arteries and veins. In addition to illustrating exact constraint checking methods, this work illustrates how the details of an application may reflect back a requirement to revise the design of the ontology itself. PMID:19248842

Kalet, Ira J; Mejino, Jose L V; Wang, Vania; Whipple, Mark; Brinkley, James F

2009-02-25

371

The beauty of anatomy: visual displays and surgical education in early-nineteenth-century London.  

PubMed

The early-nineteenth-century artist, anatomist, and teacher Sir Charles Bell saw anatomy and art as closely related subjects. He taught anatomy to artists and surgeons, illustrated his own anatomical texts, and wrote a treatise on the use of anatomy in art. The author explores the connections among visual displays representing human anatomy, aesthetics, and pedagogical practices for Bell and a particular group of British surgeon-anatomists. Creating anatomical models and drawings was thought to discipline the surgeon's hand, while the study of anatomy and comparative anatomy would discipline the artist's eye. And for Bell, beauty made drawings into better pedagogical tools. PMID:21804185

Berkowitz, Carin

2011-01-01

372

The microsurgical anatomy of the jugular foramen.  

PubMed

The microsurgical anatomy of the jugular foramen was studied in 10 fixed cadavers, each cadaver consisting of the whole head and neck. Five of the cadavers were injected with latex. The jugular foraminal region was exposed using the infratemporal fossa type A approach of Fisch and Pillsbury in five cadavers (10 sides) and the combined cervical dissection-mastoidectomy-suboccipital craniectomy approach in five cadavers (10 sides). The right foramen was larger than the left in seven cases (70%), equal in two cases (20%), and smaller in one case (10%). The dura covering the intracranial portal of the foramen had two perforations, a smaller anteromedial perforation through which passed the ninth cranial nerve (CN IX), and a larger posterolateral perforation, through which passed the 10th and 11th cranial nerves (CNs X and XI) and the distal sigmoid sinus. The perforations were separated by a fibrous septum in 16 specimens (80%). After exiting the posterior fossa, CNs IX, X, and XI all lay anteromedial to the superior jugular bulb (SJB) within the jugular foramen. The inferior petrosal sinus (IPS) entered the foramen between CNs IX and X in most cases; however, in 10% of our cases it entered the foramen between CNs X and XI, and in 10% it entered the foramen caudal to CN XI. The IPS terminated in the SJB in 90% of our cases; in 40%, the IPS termination consisted of multiple channels draining into both the SJB and internal jugular vein. This study shows that the arrangement of the neurovascular structures within the jugular foramen does not conform to the hitherto widely accepted notion of discrete compartmentalization into an anteromedial pars nervosa containing CN IX and the IPS and a posterolateral pars venosa containing the SJB, CNs X and XI, and the posterior meningeal artery. PMID:7472562

Ayeni, S A; Ohata, K; Tanaka, K; Hakuba, A

1995-11-01

373

A systems biology representation of developmental anatomy  

PubMed Central

The formation of any tissue involves differentiation, cell dynamics and interactions with adjacent tissues. This paper suggests that the complexity of the system as a whole can be represented as a mathematical graph, that is, a set of connected triples of the general form [term] [term]. Computationally, such graphs are widely used for modeling data; visually, they form hierarchies and networks. For morphogenesis, the triples are of the general structure , where nouns cover tissues, molecules and networks and verbs describe processes such as moves, differentiates, grows and apoptoses. The paper considers the general formalism of graphs, where graphs are already used in biology, and how developmental anatomy may be described using this format. Representing morphogenesis as a visual graph is complicated as the formalism has to incorporate tissue types, molecular signals, networks, dynamic processes and some aspects, at least, of tissue geometry. The formation of a capillary sprout is chosen as an example of how this complexity can be represented graphically, with colour used to distinguish tissues and molecules. There are three key benefits, beyond its compactness, in using the graph formalism of morphogenesis to complement experimentation. First, it emphasizes the distributed nature of causality in morphogenesis. Secondly, producing all the triples for the visual graph requires explicit formalization of each aspect of the process, and this, in turn, often exposes gaps in knowledge and so suggests new experiments. Thirdly, once the graph has been formalized, triples can be annotated with associated information or IDs (e.g. cell types, publications, gene-expression data) that link to external online resources that may be regularly updated. Such annotations allow the graph to be viewed as a self-maintaining review. The graph approach sees dynamic processes as the drivers of developmental momentum and, because the same processes are used many times during development, it seems appropriate to view them as modules and their underlying networks as genomic subroutines.

Bard, Jonathan

2011-01-01

374

The surgical anatomy of varicose veins.  

PubMed

Varicose veins are managed largely in ignorance of important aspects of normal anatomy. In a study of 60 dissected legs the following observations were made: 1. The long saphenous vein--normally lies on the deep fascia enclosed with an envelope of fibrous tissue, which presumably compresses the vein rhythmically on exercise to aid centripetal flow. Thick walled and straight it is never varicose, and, communicating regularly with only one or two of the 60 or so perforating veins in the lower limb, its removal by stripping in operations for varicose veins is unjustifiable. In 18% of legs its femoral part is thin walled, superficial, and sometimes multipartite: in such legs varicose veins are commoner than usual, a point of aetiological interest. 2. The tributaries of the long saphenous vein--below the knee normally drain indirectly into it via an arch vein lying parallel but in a posterior and superficial plane, communicating with it both above and below. To reach it, for instance, the pre-tibial tributaries must cross the long saphenous vein. Varicosities of these tributaries and the arch vein therefore overlie the long saphenous vein and are sometimes attributed to it. Similarly the upper end of the arch vein is often erroneously thought to be the long saphenous vein itself dilated up to an incompetent thigh perforator. 3. Perforating veins--are found all over the limb but mainly at intermuscular septa. Minor ones communicate with small muscle veins, major ones with the main deep veins. The major ones medially above the ankle differ from the rest in running a short (1 cm) and unprotected course from subcutaneous fat to posterior tibial veins through the wide gap between soleus and tibia. They are therefore peculiarly susceptible to damage, and their incompetence is peculiarly direct an its effect, which anatomical weakness may account for the prevalence of medial venous ulceration. PMID:7071165

Thomson, H

375

Ocular comparative anatomy of the family Rodentia.  

PubMed

There is little information regarding ocular anatomy and histology in many of the rodent species. Histological analyses for morphologic features were performed in 31 globes from 18 rodent species submitted to and archived at the Comparative Ocular Pathology Laboratory of Wisconsin. The following measurements were taken: thickness of the cornea, corneal epithelium, corneal stroma, Descemet's membrane, and retina. H&E sections were evaluated for the following anatomical features: presence of pigmented epithelial cells in the peripheral cornea, presence and location of Schlemm's canal, presence of iridal sphincter and dilator and ciliary body muscles, presence of pars plicata and plana, presence of retinal vessels, presence of lamina cribrosa, and presence of tapetum lucidum. The springhaas was the only rodent in our collection that presented a well-developed tapetum lucidum fibrosum. The presence of retinal vessels was variable: vessels were observed in all of the members of the mouse-related clade, except the springhaas and the beaver, in all of the squirrel-related clade members, and in none of the Ctenohystrica. In the flying squirrels, blood vessels extended to the outer limiting membrane in the photoreceptor layer. Beavers, chinchillas, capybara, and guinea pigs lacked vessels within the retina; however, they had vessels within the optic nerve head. Ground squirrels have an optic nerve head, which is linear in the horizontal plane and an asymmetric retina. The tree-dwelling squirrels have a rounded but still elongated optic nerve, and the flying squirrel has a round optic nerve head like all the other rodents. PMID:23734597

Rodriguez-Ramos Fernandez, Julia; Dubielzig, Richard R

2013-06-05

376

Anatomy teaching with portable ultrasound to medical students  

PubMed Central

Background Medical students as future clinicians will apply their anatomy knowledge in medical imaging. There are various radiological resources available for the medical students to learn anatomy and contextualise it to the clinical setting. Ultrasound is a safe and non- invasive imaging procedure commonly used in clinical practice. This study aimed to use portable ultrasound and evaluate its impact as an adjunct to cadaveric anatomy teaching together with cross sectional anatomy images and line diagrams. Methods Ultrasound teaching was incorporated into upper limb and lower limb anatomy practical dissecting room sessions. The number of medical students who participated was 121 students from the year 2008 - 2009 and 94 students from the year 2009- 2010. The students were divided into groups of 15-20. Initially ultrasound demonstration was carried out on a volunteer and then the students were given the opportunity to use the ultrasound and identify normal anatomical structures visualized on images. For the students in the year 2009- 2010, ultrasound teaching was supplemented with cross sectional anatomy images and line diagrams. Questionnaires were distributed with seven questions rated using four point Likert scale and free text. Qualitative data was analysed using 2- proportion Z test and Fischer's exact test. Results The number of students in the 2009-2010 year group who were confident in interpreting ultrasound images increased significantly when compared to the 2008-2009 year group of students. The majority of students were able to identify structures like bone, muscles and blood vessels on ultrasound images. There was a significant increase in the number of students who found the ultrasound teaching useful and also those who regarded ultrasound to have improved understanding of anatomy considerably. Conclusions Ultrasound acts as a useful adjunct to teach anatomy in a clinical context to medical students. The use of cross sectional anatomy images and line diagrams together can aid ultrasound image orientation of structures during these sessions. Early exposure to this imaging technology may prime students for later encounters with ultrasound during clinical practice.

2012-01-01

377

NCI: Research Resources > Resources by Category  

Cancer.gov

This resource provides an overview of the Community Networks Program, including the goals and phases of research; descriptions of the 25 projects; and descriptions and contact information about the funded institutions and principal investigators.

378

Chromosome abnormalities in 10 lung cancer cell lines of the NCI-H series analyzed with spectral karyotyping  

Microsoft Academic Search

The karyotypes of 10 lung cancer cell lines of the NCI-H series were analyzed with spectral karyotyping (SKY): 7 non-small lung cancer (NSCLC) lines and 3 small cell lung cancer (SCLC) lines. Modal chromosome number ranged from 42 (NCI-H2171) to 72 (NCI-H2126). All lines showed at least six structural abnormalities, and most had amplifications visible as double minutes or homogeneously

Mira Grigorova; Rachel C. Lyman; Carlos Caldas; Paul A. W. Edwards

2005-01-01

379

NCI Launches a Pilot of Its Community Cancer Centers Program to Bring Quality Cancer Care to All  

Cancer.gov

NCI today launched the three year pilot phase of a new program that will help bring state-of-the-art cancer care to patients in community hospitals across the United States. The National Cancer Institute Community Cancer Centers Program (NCCCP) is designed to encourage the collaboration of private-practice medical, surgical, and radiation oncologists - with close links to NCI research and to the network of 63 NCI-designated Cancer Centers principally based at large research universities.

380

Ontology-Enriched Visualization of Human Anatomy.  

National Technical Information Service (NTIS)

The project focuses on the problem of presenting a human anatomical 3D model associated with other types of human systemic information ranging from physiological to anatomical information while navigating the 3D model. We propose a solution that integrate...

2005-01-01

381

Interoperability and Semantics — CBIIT: Welcome to the NCI Center for Biomedical Informatics and Information Technology  

Cancer.gov

The NCI semantic infrastructure includes end-user applications, services, and content for helping to achieve interoperability, data integration, and data sharing through the use of metadata, models, and controlled terminology.

382

NCI at AACR 2012: Supporting the Journey from Bench to Bedside  

Cancer.gov

The National Cancer Institute (NCI) will be participating at the American Association for Cancer Research's (AACR) 103rd Annual Meeting from March 31-April 4, 2012 at McCormick Place in Chicago, Illinois.

383

NCI/CPFP - 2010 Application Catalog - Program Description - Additional Research Opportunities  

Cancer.gov

Skip navigation. Table of Contents Director's Message Staff Profiles Program Description Program Information Guidelines for Application Preceptorships Bibliography Post-Fellowship Employment Life Outside the NCI Previous Page | Next Page Application

384

NCI-CCR Pediatric Oncology Branch: Neurobehavioral Program - Pam Wolters, Ph.D., Section Head  

Cancer.gov

Pam Wolters, Ph.D., a licensed psychologist and staff scientist in the Pediatric Oncology Branch (POB) of the National Cancer Institute (NCI), is co-director of the Behavioral Sciences Core and head of the Neurobehavioral Program.

385

NCI Researchers Uncover Unusual Association Between Cell Survival Proteins and Ovarian Cancer Aggressiveness  

Cancer.gov

An international scientific team led by researchers at the NCI has found that the elevated levels of certain proteins typically associated with keeping cancer cells alive may actually correspond with improved patient survival in ovarian cancer.

386

ORI Reports Fabricated and/or Falsified Data for Three Patients on NCI-Sponsored Studies  

Cancer.gov

The Federal Government's Office of Research Integrity (ORI) has reported findings of scientific misconduct on the part of a data manager who worked at hospitals conducting breast cancer treatment studies sponsored by the National Cancer Institute (NCI)

387

SAIC/NCI-Frederick’s Nanotechnology Characterization Lab (NCL) is pleased to announce that Dr  

Cancer.gov

Dr. Martin Fritts, Senior Principal Scientist and Co-Founder of the NCL, Receives the 2010 ASTM International President’s Leadership Award SAIC/NCI-Frederick’s Nanotechnology Characterization Lab (NCL) is pleased to announce that Dr. Martin Fritts

388

Dinah Singer Named New Director of NCI's Division of Cancer Biology  

Cancer.gov

The National Cancer Institute (NCI) today named Dinah S. Singer, Ph.D., a well-recognized researcher in studies of transcriptional control in the immune system, as director of its Division of Cancer Biology.

389

New Joint Program Announced by FDA and NCI Holds Promise for Cancer  

Cancer.gov

The Food and Drug Administration (FDA) and the National Cancer Institute (NCI) announced today a new joint research and clinical program that holds great promise for developing better and more targeted treatments for cancer.

390

Agenda for the Second NCI Epidemiology Leadership Workshop: Understudied Rare Cancers  

Cancer.gov

Skip to Main Content at the National Institutes of Health | www.cancer.gov Epidemiology and Genomics Research In NCI's Division of Cancer Control and Population Sciences Menu Search EGRP Site: Home About the Program Mission & Vision Organizational

391

Cognitive learning: new media to visualize human anatomy  

PubMed

The knowledge of anatomy is essential for all health care professionals. However, it has become extremely difficult to find qualified instructors who can fit into an academic environment that stresses research funding and publications for promotion. In addition, dissection, which is the best way to learn anatomy, is expensive, labor intensive and time consuming. We are developing electronic visualization media to augment the teaching and learning of human anatomy. We are creating programs that reveal 3-D spatial relationships by allowing the user to both deconstruct (dissect) and reconstruct discrete regions of the body and which use labeling paradigms that are efficient, yet informative. We have also incorporated principles from cognitive psychology showing that learning is most efficient when the process is interactive and the student is thoroughly engaged in the subject matter. PMID:11080031

Soliz; Sinav; Ambron; Molholt

2000-01-01

392

Spatial Abilities of Expert Clinical Anatomists: Comparison of Abilities Between Novices, Intermediates, and Experts in Anatomy  

NSDL National Science Digital Library

This article describes a study with two aims: To determine if spatial ability is a learned or inherent facet in learning anatomy and to ascertain if there is any difference in spatial ability between experts and novices in anatomy.

Ruth Fernandez (University of Southampton Centre for Learning Anatomical Sciences); Itiel Dror (University College London Institute of Cognitive Neuroscience); Claire Smith (Cognitive Consultants International Ltd)

2011-01-17

393

NCI Funded Research Portfolio - ZIA BC 010878 Detail  

Cancer.gov

We identified microRNA expression patterns associated with diagnosis, prognosis, and therapeutic outcome in colon adenocarcinoma. MircoRNAs associated with diagnosis and prognosis were first identified in a cohort recruited from the NCI-Maryland Colon Cancer Case-Control Study. These findings were validated in an independent cohort recruited from Hong Kong. This study was the largest to date profiling microRNA expression patterns in colon tumors and the only study to analyze associations with prognosis or therapeutic outcome. Thirty-seven microRNAs were differentially expressed in tumors.

394

NCI Funded Research Portfolio - Z01 BC 010878 Detail  

Cancer.gov

We identified microRNA expression patterns associated with diagnosis, prognosis, and therapeutic outcome in colon adenocarcinoma. MircoRNAs associated with diagnosis and prognosis were first identified in a cohort recruited from the NCI-Maryland Colon Cancer Case-Control Study. These findings were validated in an independent cohort recruited from Hong Kong. This study was the largest to date profiling microRNA expression patterns in colon tumors and the only study to analyze associations with prognosis or therapeutic outcome. Thirty-seven microRNAs were differentially expressed in tumors.

395

YouTube: An emerging tool in anatomy education.  

PubMed

The use of online social networks in medical education can remodel and enhance anatomy teaching and learning; one such network is the video-sharing site YouTube. Limited research in the literature exists on the use of YouTube as a platform for anatomy education. The aim of this study is to assess student's perceptions and patterns of usage of this resource, as well as the effectiveness of YouTube videos within a problem-based learning (PBL) curriculum. The study was conducted on 91 second-year medical students for whom video links were suggested throughout the academic year. In addition, the Human Anatomy Education (HAE) Channel was launched on YouTube to support classroom teaching with videos that emphasized applied aspects of anatomy. The results demonstrated that 98% of the students used YouTube as an online information resource, albeit in different frequencies. Out of the 86% who have been to the HAE Channel, 92% agreed/strongly agreed that the channel helped them learn anatomy. The study also reports the popularity of and awareness about using YouTube as a social network as well as in learning. Based on these findings, YouTube can be considered as an effective tool to enhance anatomy instruction if the videos are scrutinized, diversified, and aimed toward course objectives. Faculty of average computer literacy should be enabled to produce videos on their own YouTube channels to support independent learning and integration in a PBL curriculum. The methods described for capturing and editing the videos can be used as a prototype. PMID:22383096

Jaffar, Akram Abood

2012-03-01

396

About NCIP — CBIIT: Welcome to the NCI Center for Biomedical Informatics and Information Technology  

Cancer.gov

Following last year's report from the Board of Scientific Advisors Working Group, NCI has undertaken a thorough reassessment of the Cancer Biomedical Informatics Grid (caBIG) program and begun charting a new course for the informatics infrastructure that will support the NCI's research programs. While many of the founding principles of caBIG remain valid, a new vision for interoperable biomedical information systems, built on community-driven data standards, is needed to support the cancer research enterprise.

397

NCI ofrece apoyo a quienes están necesitados después del huracane Katrina  

Cancer.gov

El Instituto Nacional del Cáncer (NCI), parte de los Institutos Nacionales de la Salud (NIH), está empeñado en ayudar a las miles de personas que han sido asoladas por los efectos del huracán Katrina. NCI está tratando de llegar a los públicos diversos para proporcionarles información relacionada con el cáncer que pueda ser compartida con exactitud y efectividad con quienes han sido afectados por el huracán.

398

NCI ofrece apoyo a quienes están necesitados después de los huracanes Katrina y Rita  

Cancer.gov

El Instituto Nacional del Cáncer (NCI), parte de los Institutos Nacionales de la Salud (NIH), está empeñado en ayudar a las miles de personas que han sido asoladas por los efectos de los huracánes Katrina y Rita. NCI está tratando de llegar a los públicos diversos para proporcionarles información relacionada con el cáncer que pueda ser compartida con exactitud y efectividad con quienes han sido afectados por los huracánes.

399

NCI: SBIR & STTR - Find Funding - Contracts - 271 Development of Molecular Pharmacodynamic Assays for Targeted Therapies  

Cancer.gov

The NCI requests that qualified small businesses submit proposals to develop pharmacodynamic assays for measuring drug response of a number of high-priority molecular targets. A list of the targets of interest to NCI is shown below. The short-term goal of this contract topic is to develop new robust, validated assays to measure molecular-level responses to treatment in conjunction with preclinical development of new candidate therapeutic agents.

400

Control del cáncer y salud mundial: noticia del Instituto Nacional del Cáncer (NCI)  

Cancer.gov

En combinación con una reunión de alto nivel de las Naciones Unidas sobre enfermedades no transmisibles en países en vías de desarrollo, el doctor Harold Varmus, director del NCI, y el doctor Ted L. Trimble, del NCI, han publicado un comentario en Science Translational Medicine sobre “La integración del control del cáncer en la salud mundial" (Integrating Cancer Control into Global Health).

401

Data Display and Analysis Strategies for The NCI Disease-Oriented in Vitro Antitumor Drug Screen  

Microsoft Academic Search

\\u000a For the past five years, NCI staff and collaborators have been pursuing the development and implementation of an unprecedented\\u000a new investigational antitumor drug discovery screen. These efforts have not only been controversial, but have also been undertaken\\u000a during an era of diminishing resources for antitumor drug screening and drug development at NCI. Moreover, numerous unanticipated\\u000a obstacles, not only in the

M. R. Boyd; K. D. Paull; L. R. Rubinstein

402

NCI: SBIR & STTR - Past Funding Opportunities - Contracts - 229 Development of Molecular Pharmacodynamic Assays for Targeted Therapies  

Cancer.gov

The NCI requests that qualified small businesses submit proposals to develop pharmacodynamic assays for measuring a number of high-priority molecular targets. (For a list of the targets of interest to NCI, please click here). The short term goal of this contract is to develop new rigorous, validated assays to measure molecular-level response to treatment in conjunction with preclinical development of new candidate therapeutic agents.

403

Aerial organ anatomy of Smilax syphilitica (Smilacaceae).  

PubMed

Smilax L. in Brazil is represented by 32 taxa and it is a taxonomically difficult genus because the plants are dioecious and show wide phenotypic variation. The analysis and use of leaf anatomy characters is recognized as a frequently successful taxonomic method to distinguish between individual taxon, when floral material is absent or minute differences in flowers and foliage exist such as in Smilax. The aim of this study was to characterize the anatomical features of the aerial organs in Smilax syphilitica collected from the Atlantic Rainforest, in Santa Teresa-ES and the Smilax aff. syphilitica from the Amazon Rainforest, in Manaus, Brazil. For this, a total of three samples of Smilax were collected per site. Sample leaves and stems were fixed with FAA 50, embedded in historesin, sectioned on a rotary microtome, stained and mounted in synthetic resin. Additionally, histochemical tests were performed and cuticle ornamentation was analyzed with standard scanning electron microscopy. S. syphilitica and S. aff. syphilitica differed in cuticle ornamentation, epidermal cell arrangement and wall thickness, stomata type and orientation, calcium oxalate crystal type, and position of stem thorns. Leaf blades of S. syphilitica from the Amazon Rainforest have a network of rounded ridges on both sides, while in S. aff. syphilitica, these ridges are parallel and the spaces between them are filled with numerous membranous platelets. Viewed from the front, the epidermal cells of S. syphilitica have sinuous walls (even more pronounced in samples from the Amazon); while in S. aff. syphilitica, these cells are also sinuous but elongated in the cross-section of the blade and arranged in parallel. Stomata of S. syphilitica are paracytic, whereas in S. aff. syphilitica, are both paracytic and anisocytic, and their polar axes are directed towards the mid-vein. Calcium oxalate crystals in S. syphilitica are prisms, whereas in S. aff. syphilitica, crystal sand. Thorns occur in nodes and internodes in S. syphilitica but only in internodes in S. af. syphilitica. These features have proven to be of diagnostic value and may support a separation into two species, but future studies are needed to confirm that S. aff. syphilitica is indeed a new taxon. PMID:23025085

Silva, João Marcelo; Andreata, Regina Helena Potsch; Appezzato-da-Glória, Beatriz

2012-09-01

404

The adolescent female: Breast and reproductive embryology and anatomy.  

PubMed

Congenital breast and genital tract anomalies are seen frequently in the care of children and adolescents. Breast and internal gynecologic anomalies more often present in adolescence than in early childhood. Management is best delivered through a multidisciplinary team approach. Carefully timed surgical intervention is of importance to optimize psychological, aesthetic and functional outcomes. An understanding of the female breast and genital tract embryology and anatomy is important for a meticulous clinical examination and appropriate surgical treatment. This article will review the normal embryology and anatomy of the adolescent female breast and genital tract. PMID:22997043

Lemaine, Valerie; Simmons, Patricia S

2012-09-19

405

The clivus: anatomy, normal variants and imaging pathology.  

PubMed

The clivus is one of the most central parts of the skull base. As diseases of the clivus evade clinical evaluation imaging plays a pivotal role in establishing a diagnosis. This article combines the description of anatomy and pathology with an extensive pictorial essay. Starting with the development and normal macroscopic anatomy of the clivus the reader is then introduced to a large variety of normal variations and developmental disorders some of them with clinical significance. Typical examples of non-neoplastic and neoplastic masses of the clivus and their differential diagnoses are provided. The article concludes with a review of inflammatory disease and trauma. PMID:21710384

Hofmann, E; Prescher, A

2011-06-28

406

Functional anatomy and biomechanics of shoulder stability in the athlete.  

PubMed

The glenohumeral joint provides greater freedom of motion than any other joint in the body at the expense of decreased stability. Shoulder instability can occur in overhead throwing athletes (chronic, overuse injuries) but more commonly occurs in contact athletes (acute traumatic dislocations). Our understanding of the anatomy and pathologic entities has evolved significantly since initial descriptions of shoulder instability and this has facilitated an evolving repertoire of treatment options. This article reviews the functional anatomy and biomechanics of shoulder stability and outlines the bony and soft tissue lesions associated with shoulder instability in the athlete. PMID:24079424

Murray, Iain R; Goudie, Ewan B; Petrigliano, Frank A; Robinson, C Michael

2013-10-01

407

The Beauty of Anatomy: Visual Displays and Surgical Education in Early-Nineteenth-Century London  

Microsoft Academic Search

Summary:The early-nineteenth-century artist, anatomist, and teacher Sir Charles Bell saw anatomy and art as closely related subjects. He taught anatomy to artists and surgeons, illustrated his own anatomical texts, and wrote a treatise on the use of anatomy in art. The author explores the connections among visual displays representing human anatomy, aesthetics, and pedagogical practices for Bell and a particular

Carin Berkowitz

2011-01-01

408

NCI Funded Research Portfolio - ZIABC011413 Detail  

Cancer.gov

This project is a combination of a clinical trial of infusions of autologous anti-CD19 chimeric-antigen-receptor-transduced T cells and laboratory experiments performed on cells obtained from patients that received infustions of the chimeric-antigen-receptor-transduced T cells. During 2012 this project resulted in a Plenary Paper published in Blood entitled "B-cell Depletion and Remissions of Malignancy Along With Cytokine-associated Toxicity in a Clinical Trial of Anti-CD19 Chimeric-antigen-receptor-transduced T cells".

409

Web-delivery of anatomy video clips using a CD-ROM.  

PubMed

Until recently, anatomists had no doubt that the teaching of anatomy had to include cadaver dissection. However, due to a changing academic environment as well as challenged financial institutional resources, computer-assisted instruction was introduced into medical curriculum in an attempt to reduce the cost and the time committed to cadaver dissection. Computer-assisted instruction included locally created or commercially available anatomy software, Internet sites, and databases of digital images of cadaveric structures such as the Virtual Human Project. However, until now, bandwidth limitations have not allowed effective visualization in real-time over the Internet of recorded videos or 3D animations reconstructed from a database. We describe how to successfully link and display large video clips stored on a CD-ROM in support of lectures saved in HTML format on the Internet. This process, described in its totality, allows students to access audiovisual files on a CD-ROM through the Internet, from any location, with either Macintosh or Windows computers, using the Netscape browser. This process allowed us to circumvent one of the most significant limitations of the computer-assisted instruction on the Internet by delivering full audio and visual information on demand, as it would happen in a traditional classroom. PMID:10815812

Bacro, T; Gilbertson, B; Coultas, J

2000-04-15

410

Effect of the Use of Instructional Anatomy Videos on Student Performance  

NSDL National Science Digital Library

This article describes a study investigating the effect of medical students watching (independently) anatomy dissection videos as a supplement to a reduced anatomy curriculum. The same study was conducted in a radiology medical school course. The outcomes of the study are discussed in each course, including the benefit on student performance in the anatomy course.

2008-08-01

411

Living AnatoME: Teaching and Learning Musculoskeletal Anatomy through Yoga and Pilates  

ERIC Educational Resources Information Center

|Living AnatoME, a program designed in 2004 by two medical students in conjunction with the Director of Anatomy, teaches musculoskeletal anatomy through yoga and Pilates. Previously offered as an adjunct to the Gross Anatomy course in 2007, Living AnatoME became an official part of the curriculum. Previous research conducted on the program…

McCulloch, Carrie; Marango, Stephanie Pieczenik; Friedman, Erica S.; Laitman, Jeffrey T.

2010-01-01

412

Surgical Clinical Correlates in Anatomy: Design and Implementation of a First-Year Medical School Program  

ERIC Educational Resources Information Center

|Medical students state the need for a clinically oriented anatomy class so to maximize their learning experience. We hypothesize that the first-year medical students, who take the Surgical Clinical Correlates in Anatomy program, will perform better than their peers in their anatomy course, their surgical clerkships and ultimately choose surgical…

Haubert, Lisa M.; Jones, Kenneth; Moffatt-Bruce, Susan D.

2009-01-01

413

The Weak Relationship between Anatomy Competence and Clinical Skills in Junior Medical Students  

ERIC Educational Resources Information Center

|In modern curricula, the early integration of anatomy and clinical skills education at undergraduate level is seen as important. However, the direct relationship between medical students' competence in anatomy, and their clinical proficiency during early undergraduate years, has scarcely been studied. In this study, the marks for anatomy and…

Schoeman, Scarpa; Chandratilake, Madawa

2012-01-01

414

The Anatomy Competence Score--A New Marker for Anatomical Ability  

ERIC Educational Resources Information Center

|The assessment of students' ability in gross anatomy is a complex process as it involves the measurement of multiple facets. In this work, the authors developed and introduced the Anatomy Competence Score (ACS), which incorporates the three domains of anatomy teaching and assessment namely: theoretical knowledge, practical 3D application of the…

Schoeman, Scarpa; Chandratilake, Madawa

2012-01-01

415

The Effects of Viewing Grey's Anatomy on Perceptions of Doctors and Patient Satisfaction  

Microsoft Academic Search

The present investigation applies cultivation theory to describe the role of viewing Grey's Anatomy on patients' predispositions. Results demonstrate that heavy viewers of Grey's Anatomy perceive this program to be credible. Credibility was positively associated with a perception that real-world doctors are courageous. A direct association did not emerge between Grey's Anatomy viewing and a perception that doctors are courageous,

Brian L. Quick

2009-01-01

416

Voxel-based computational models of real human anatomy: a review  

Microsoft Academic Search

Computational models of human anatomy are mathematical representations of human anatomy designed to be used in dosimetry calculations. They have been used in dosimetry calculations for radiography, radiotherapy, nuclear medicine, radiation protection and to investigate the effects of low frequency electromagnetic fields. Tomographic medical imaging techniques have allowed the construction of digital three-dimensional computational models based on the actual anatomy

Martin Caon

2004-01-01

417

Building the Body: Active Learning Laboratories that Emphasize Practical Aspects of Anatomy and Integration with Radiology  

ERIC Educational Resources Information Center

|Active learning exercises were developed to allow advanced medical students to revisit and review anatomy in a clinically meaningful context. In our curriculum, students learn anatomy two to three years before they participate in the radiology clerkship. These educational exercises are designed to review anatomy content while highlighting its…

Zumwalt, Ann C.; Lufler, Rebecca S.; Monteiro, Joseph; Shaffer, Kitt

2010-01-01

418

NCI Funded Research Portfolio - ZICBC011040 Detail  

Cancer.gov

The Clinical Molecular Profiling Core (CMPC) is a collaborative core that seeks to go beyond the common service paradigm of other cores. The expertise of the personnel allows us to be involved from the start of a project, such as the protocol development, though performance of the assay and biostatistical analysis.

419

NCI Funded Research Portfolio - ZIABC010946 Detail  

Cancer.gov

Summary Two strains of mice were used in this project. Female C3H and CBA mice were exposed to a total body dose of radiation of 3 Gy with or without Tempol supplementation in the animal's food. Immediately following the radiation exposure, animals were be placed on either control or TP-containing food.

420

NCI Funded Research Portfolio - ZIABC010283 Detail  

Cancer.gov

The major focus of this project is to understand how cells monitor and repair DNA damage. Defects in either the surveillance or repair of damaged DNA can lead to chromosomal instability and cancer. For example, inherited disorders affecting cellular responses to DNA damage, such as Nijmegen breakage syndrome and ataxia telangiectasia are characterized by increased susceptibility to lymphoid cancer, extreme radiation sensitivity and immunodeficiency.

421

NCI Funded Research Portfolio - ZIABC011411 Detail  

Cancer.gov

A widespread reduction to practice for an approach that employs genetically engineered mouse (GEM) cancer models for more predictive cancer drug efficacy evaluation is largely impeded by significant costs intrinsic to operations involving GEM animals but also due to frequent shortage of appropriate expertise in supporting complex genetics projects.

422

NCI Funded Research Portfolio - ZIABC010957 Detail  

Cancer.gov

As noted in the goals and objectives stated for this project, it aims to create new models that test distinct hypotheses and provide new understandings for development of novel strategies in the treatment of lymphoma, myeloma, leukemia, breast cancer and renal cancer by hematopoietic stem cell transplantation. Hematopoietic stem cell transplant treatment of these diseases generally results in lymphopenia and immune compromise.

423

Digital dissection system for medical school anatomy training  

NASA Astrophysics Data System (ADS)

As technology advances, new and innovative ways of viewing and visualizing the human body are developed. Medicine has benefited greatly from imaging modalities that provide ways for us to visualize anatomy that cannot be seen without invasive procedures. As long as medical procedures include invasive operations, students of anatomy will benefit from the cadaveric dissection experience. Teaching proper technique for dissection of human cadavers is a challenging task for anatomy educators. Traditional methods, which have not changed significantly for centuries, include the use of textbooks and pictures to show students what a particular dissection specimen should look like. The ability to properly carry out such highly visual and interactive procedures is significantly constrained by these methods. The student receives a single view and has no idea how the procedure was carried out. The Department of Anatomy at Mayo Medical School recently built a new, state-of-the-art teaching laboratory, including data ports and power sources above each dissection table. This feature allows students to access the Mayo intranet from a computer mounted on each table. The vision of the Department of Anatomy is to replace all paper-based resources in the laboratory (dissection manuals, anatomic atlases, etc.) with a more dynamic medium that will direct students in dissection and in learning human anatomy. Part of that vision includes the use of interactive 3-D visualization technology. The Biomedical Imaging Resource (BIR) at Mayo Clinic has developed, in collaboration with the Department of Anatomy, a system for the control and capture of high resolution digital photographic sequences which can be used to create 3-D interactive visualizations of specimen dissections. The primary components of the system include a Kodak DC290 digital camera, a motorized controller rig from Kaidan, a PC, and custom software to synchronize and control the components. For each dissection procedure, the images are captured automatically, and then processed to generate a Quicktime VR sequence, which permits users to view an object from multiple angles by rotating it on the screen. This provides 3-D visualizations of anatomy for students without the need for special '3-D glasses' that would be impractical to use in a laboratory setting. In addition, a digital video camera may be mounted on the rig for capturing video recordings of selected dissection procedures being carried out by expert anatomists for playback by the students. Anatomists from the Department of Anatomy at Mayo have captured several sets of dissection sequences and processed them into Quicktime VR sequences. The students are able to look at these specimens from multiple angles using this VR technology. In addition, the student may zoom in to obtain high-resolution close-up views of the specimen. They may interactively view the specimen at varying stages of dissection, providing a way to quickly and intuitively navigate through the layers of tissue. Electronic media has begun to impact all areas of education, but a 3-D interactive visualization of specimen dissections in the laboratory environment is a unique and powerful means of teaching anatomy. When fully implemented, anatomy education will be enhanced significantly by comparison to traditional methods.

Augustine, Kurt E.; Pawlina, Wojciech; Carmichael, Stephen W.; Korinek, Mark J.; Schroeder, Kathryn K.; Segovis, Colin M.; Robb, Richard A.

2003-05-01

424

An innovative technique for displaying three dimensional radiographic anatomy of synovial structures in the equine distal limb.  

PubMed

Radiography is the most commonly applied imaging modality in equine practice and forms an essential part of the diagnostic work-up of lame horses. Radiographic signs of musculoskeletal pathology are frequently localized at sites of soft tissue attachment, which are often not clearly visible on radiographs. Different lesions carry different prognoses and require a variety of treatments, and a good knowledge of the position of the synovial structures in the distal limb of the horse is essential for practitioners in the interpretation of radiographs. This study describes a new technique for creating three-dimensional (3D) models of the synovial structures and superimposing them onto radiographs for the purpose of teaching radiographic anatomy. A set of standard radiographs was acquired of the metacarpophalangeal and the distal interphalangeal joints of a fresh cadaver leg while the leg was positioned in a material-testing machine to mimic the weight-bearing horse. Computed tomography of the same regions was performed after injection of negative contrast medium into the joints. 3D reconstructions of the joints were created using grayscale thresholding and polynomial surface meshing in Mimics. The resulting 3D reconstructions were superimposed on top of the radiographs using Adobe Photoshop CS3 Extended, thus allowing the visualization of the joint anatomy in relation to the bone on all projections. The main advantage of this technique is that it allows synovial structures to be visualized on radiographs where they are normally indistinct, which will serve as a teaching aid for anatomy. PMID:19999341

Smith, Alexander J; Felstead, Christopher W; Lawson, Jack S; Weller, Renate

425

Functional anatomy of thalamus and basal ganglia  

Microsoft Academic Search

Thalamus. The human thalamus is a nuclear complex located in the diencephalon and comprising of four parts (the hypothalamus, the epythalamus, the ventral thalamus, and the dorsal thalamus). The thalamus is a relay centre subserving both sensory and motor mechanisms. Thalamic nuclei (50-60 nuclei) project to one or a few well-defined cortical areas. Multiple cortical areas receive afferents from a

María-Trinidad Herrero; Carlos Barcia; Juana Mari Navarro

2002-01-01

426

Resilience Does Not Predict Academic Performance in Gross Anatomy  

ERIC Educational Resources Information Center

|Few studies have evaluated resilience in an academic environment as it relates to academic success or failure. This work sought to assess resilience in regular and remedial students of gross anatomy during the first and second semesters of medical school and to correlate this personal trait with academic performance. Two groups of students were…

Elizondo-Omana, Rodrigo Enrique; Garcia-Rodriguez, Maria de los Angeles; Hinojosa-Amaya, Jose Miguel; Villarreal-Silva, Eliud Enrique; Avilan, Rosa Ivette Guzman; Cruz, Juan Jose Bazaldua; Guzman-Lopez, Santos

2010-01-01

427

When Young Children Explore Anatomy: Dilemma or Development?  

ERIC Educational Resources Information Center

Offers advice to parents and teachers on addressing children's natural curiosities about their own bodies and those of others. Recommends using anatomically correct terms and dolls, and children's anatomy books; advises what to do when children engage in sex play, self-exploration, and masturbation, or use toilet language. (DLH)

Petty, Karen

2001-01-01

428

The foundational model of anatomy in OWL: Experience and perspectives  

Microsoft Academic Search

We present the method developed for migrating the Foundational Model of Anatomy (FMA) from its representation with frames in Proteg´ et o its logical representation in OWL and our experience in reasoning with it. Despite the extensive use of metaclasses in Proteg´ e, it proved possible to convert the FMA from Prot´ ege into OWL DL, while capturing most of

Christine Golbreich; Songmao Zhang; Olivier Bodenreider

2006-01-01

429

Teaching the Anatomy of a Scientific Journal Article  

ERIC Educational Resources Information Center

|To promote inquiry-based learning, the authors integrate the anatomy of a scientific journal article into their secondary science curriculum. In this article, they present three classroom activities used to teach students about the function and format of scientific journal articles. The first focuses on journal article figures, the second on…

Schinske, Jeffrey N.; Clayman, Karen; Busch, Allison K.; Tanner, Kimberly D.

2008-01-01

430

Standard methods for Apis mellifera anatomy and dissection  

Technology Transfer Automated Retrieval System (TEKTRAN)

An understanding of the anatomy and functions of internal and external structures are fundamental to many studies on the honey bee Apis mellifera. Similarly, proficiency in dissection techniques is vital for many more complex procedures. In this paper, which is a prelude to the other papers of the C...

431

Glenohumeral contact forces in reversed anatomy shoulder replacement  

Microsoft Academic Search

A major requirement to design an implant is to develop our understanding of the applied internal forces during everyday activities. In the absence of any basic apparatus for measuring forces directly, it is essential to rely on modelling. The major aim of this study was therefore to understand the biomechanical function of subjects with the reversed anatomy Bayley?Walker prosthesis, using

Milad Masjedi; Garth R. Johnson

2010-01-01

432

Bassett Collection of Stereoscopic Images of Human Anatomy  

NSDL National Science Digital Library

This website houses the Bassett Collection of Stereoscopic Images of Human Anatomy, which includes detailed drawings from 3-D photographic images initially created by Dr. David Bassett and Dr. William Gruber in 1948. Anatomical drawings and a detailed list of anatomical features specific to each structure can be found for each drawing.

David L Basset (Stanford University Anatomy)

2011-08-31

433

Wood anatomy of the Carmichaelia (Fabaceae) complex in New Zealand  

Microsoft Academic Search

Wood anatomy of Carmichaelia australis, Ca. compacta, Ca. corrugata, Ca. monroi, Ca. nana, Ca. odorata, Ca. petriei, Ca. williamsii, Chordospartium muritai, Ch. stevensonii, Corallospartium crassicaule, Notospartium carmichaeliae, N. glabrescens, and N. torulosum is described. These species share vessels with helical thickening and simple perforations; vessels, axial parenchyma, and short rays arranged in storied structure; predominantly fusiform parenchyma; and rays 1–20

P. B. Heenan

1997-01-01

434

Comparative leaf anatomy of Alpinia Roxb. species (Zingiberaceae) from China  

Microsoft Academic Search

The leaf anatomy of 20 Alpinia species from China was investigated. Results show that there is interspecific variation in the structure of the leaf midrib and petiole which can be used for species identification. Adaxial hypodermis is present in the lamina in all species of subgenus Catimbium and absent from all species of subgeneraDieramalpinia and Probolocalyx and Alpinia, excepting A.

KHATIJAH HAJI HUSSIN; CHUA TSE SENG; HALIJAH IBRAHIM; WU QI GEN; LIAO JING PING; LIU NIAN

2000-01-01

435

Anatomy Education in Namibia: Balancing Facility Design and Curriculum Development  

NSDL National Science Digital Library

This article describes the development of a gross anatomy course (lab and lecture) at a new medical school in Namibia. The goal of the article is to demonstrate how building a school from the ground up allows for a school to incorporate research based practices into a curriculum and facility structure with ease.

2011-12-26

436

Measuring higher cognitive development in anatomy and physiology students  

Microsoft Academic Search

To estimate the higher cognitive development of college science students, performance on lecture exams at different cognitive levels was measured in a two-semester sequence of anatomy and physiology at Idaho State University. Lecture exams consisted of multiple-choice test items, each classified at various cognitive levels of Bloom's Taxonomy. These included the knowledge, comprehension, application, and analysis levels. The investigation comprised

Christopher Dobson

2001-01-01

437

Teaching Bovine Abdominal Anatomy: Use of a Haptic Simulator  

ERIC Educational Resources Information Center

|Traditional methods of teaching anatomy to undergraduate medical and veterinary students are being challenged and need to adapt to modern concerns and requirements. There is a move away from the use of cadavers to new technologies as a way of complementing the traditional approaches and addressing resource and ethical problems. Haptic (touch)…

Kinnison, Tierney; Forrest, Neil David; Frean, Stephen Philip; Baillie, Sarah

2009-01-01

438

Teaching Bovine Abdominal Anatomy: Use of a Haptic Simulator  

NSDL National Science Digital Library

This article describes a new technology, haptic (touch) technology, which may supplement or replace cadaver lab exercises. Veterinary students tested the new technology during a basic bovine abdominal anatomy lab using a rectal palpation simulator. Discussions include student's positive attitude towards this technology and modes of using this technology.

Stephen Frean (Royal Veterinary College Veterinary Clinical Sciences)

2009-11-01

439

Teaching the Anatomy of a Scientific Journal Article  

ERIC Educational Resources Information Center

To promote inquiry-based learning, the authors integrate the anatomy of a scientific journal article into their secondary science curriculum. In this article, they present three classroom activities used to teach students about the function and format of scientific journal articles. The first focuses on journal article figures, the second on…

Schinske, Jeffrey N.; Clayman, Karen; Busch, Allison K.; Tanner, Kimberly D.

2008-01-01

440

Innovative activities for teaching anatomy of speech production.  

PubMed

Courses in anatomy have traditionally relied on lectures and cadaver dissection laboratories. In speech and hearing sciences, there tends to be less access to cadavers than in medical schools and other allied health professions. It is more typical to use anatomical models, diagrams and lecture slides. Regardless of the resources available, anatomy is a subject that lends itself to hands-on learning. This article briefly reviews teaching methods and describes a variety of innovative activities to enhance learning of anatomical concepts and clinical relevance of anatomy for speech production. Teaching strategies and activities were developed to capitalize on students' multimodal learning preferences as revealed by responses to a survey administered to 49 undergraduates in the beginning of an anatomy of speech production course. At the end of the semester, students completed a second survey. A five-point Likert scale was used to assess the usefulness of each activity as a learning tool or level of clinical relevance and the level of enjoyability. The responses were overwhelmingly positive with level of usefulness and level of clinical relevance rated higher on average than the level of enjoyment. PMID:20740622

Skinder-Meredith, Amy E

441

The biomechanics of reverse anatomy shoulder replacement – A modelling study  

Microsoft Academic Search

BackgroundReverse anatomy shoulder prostheses, in which a partial sphere is attached to the scapula and a socket to the humerus, have become popular for the treatment of arthritic shoulders with severe rotator cuff arthropathy. While they have been in relatively common use, their biomechanical aspects have not been fully investigated.

A. Kontaxis; G. R. Johnson

2009-01-01

442

The developmental anatomy of the neonatal glenohumeral joint  

Microsoft Academic Search

The embryologic development of the capsular ligaments, synovial lining, rotator cuff, and bony structures of the shoulder is incompletely understood. The purpose of this study is to report the gross and microscopic anatomy of the developing glenohumeral joint on the basis of dissections of fetal shoulder specimens. After Institutional Review Board approval from our hospital, 51 shoulders in 37 fetal

Stephen Fealy; Scott A. Rodeo; Edward F. Dicarlo; Stephen J. O'Brien

2000-01-01

443

Normal anatomy, variants and pitfalls on shoulder MRI  

Microsoft Academic Search

MR imaging of the shoulder is widely used for assessment of impingement and instability-related clinical conditions. The following review article demonstrates the normal anatomy, variations and classical pitfalls. In addition to classical pitfalls (sublabral hole, sublabral recess, Buford complex) the authors focus on a number of normal, bony, cartilaginous, ligamentous and tendinous structures that can simulate disease at the shoulder.

Jasna Rudez; Marco Zanetti

2008-01-01

444

A surgical training simulator for temporal bone anatomy education  

Microsoft Academic Search

This paper presents a virtual reality system that allows a user to learn accurately mimic 3D temporal bone and ear anatomy. The computer-based system simulator is helpful to medical students in identifying the anatomic structures on the view of the auditory system. The surgical training system simulator can be effectively used to anatomic training and teaching at all levels of

Wen Xie; Weijia Kong; Enmin Song; Qiang Zhang

2009-01-01

445

Functional Anatomy of Human Auditory Attention Studied with PET  

Microsoft Academic Search

Positron emission tomography was used to investigate the functional anatomy of selective auditory attention in 17 right-handed male volunteers who submitted to different tasks: silent rest (REST), listening to frequent low- or rare high-pitched tones (LIS) delivered randomly to the right or the left ear, selective auditory attention where subjects had to attend to deviants in one ear, right (ATTR)

N. Tzourio; F. El Massioui; F. Crivello; M. Joliot; B. Renault; B. Mazoyer

1997-01-01

446

Development of a Synergistic Case-Based Micro anatomy Curriculum  

ERIC Educational Resources Information Center

|This paper discusses the development of an interactive approach to teaching and assessing a micro anatomy curriculum in an innovative medical school program. As an alternative to lectures and labs, students are engaged in interactive seminars focused on discussion of clinical and research-based cases matched with normal histology and pathology…

McBride, Jennifer M.; Prayson, Richard A.

2008-01-01

447

Innovative Activities for Teaching Anatomy of Speech Production  

ERIC Educational Resources Information Center

|Courses in anatomy have traditionally relied on lectures and cadaver dissection laboratories. In speech and hearing sciences, there tends to be less access to cadavers than in medical schools and other allied health professions. It is more typical to use anatomical models, diagrams and lecture slides. Regardless of the resources available,…

Skinder-Meredith, Amy E.

2010-01-01

448

The Anatomy of Amnesia: Neurohistological Analysis of Three New Cases  

ERIC Educational Resources Information Center

|The most useful information about the anatomy of human memory comes from cases where there has been extensive neuropsychological testing followed by detailed post-mortem neurohistological analysis. To our knowledge, only eight such cases have been reported (four with medial temporal lobe damage and four with diencephalic damage). Here we present…

Gold, Jeffrey J.; Squire, Larry R.

2006-01-01

449

Anatomy and Selected Biomechanical Aspects of the Shoulder.  

ERIC Educational Resources Information Center

|This paper focuses on the anatomy and functions of the shoulder that are relevant to the evaluation and treatment of athletic injuries. A discussion is presented on the four basic components of the shoulder mechanism: (1) super structure--bony components; (2) moving parts--joints involved; (3) motor power--musculature; and (4) communications…

Keene, James S.

450

Attitudes of Healthcare Students on Gross Anatomy Laboratory Sessions  

ERIC Educational Resources Information Center

|At Chiba University, gross anatomy laboratory sessions ("laboratories") are required for physical therapy students. Though most physical therapy schools require their students to participate in laboratories so that they will better understand the structure of the human body, few data exist on the value of these laboratories specifically for…

Kawashiro, Yukiko; Anahara, Reiko; Kohno, Toshihiko; Mori, Chisato; Matsuno, Yoshiharu

2009-01-01

451

Comparative Anatomy and Morphology of Nectar-producing Melastomataceae  

Microsoft Academic Search

† Background and Aims Most neotropical Melastomataceae have bee-pollinated flowers with poricidal anthers. However, nectar rewards are known to be produced in about 80 species in eight genera from four different tribes. These nectar-producing species are pollinated by both vertebrates and invertebrates. † Methods The floral morphology and anatomy of 14 species was studied in six genera of nectar-producing Melastomataceae

ISABELA GALARDA VARASSIN; DARIN S. PENNEYS; FABIAN A. MICHELANGELI

2008-01-01

452

A digital database of wrist bone anatomy and carpal kinematics  

Microsoft Academic Search

The skeletal wrist consists of eight small, intricately shaped carpal bones. The motion of these bones is complex, occurs in three dimensions, and remains incompletely defined. Our previous efforts have been focused on determining the in vivo three-dimensional (3-D) kinematics of the normal and abnormal carpus. In so doing we have developed an extensive database of carpal bone anatomy and

Douglas C. Moore; Joseph J. Crisco; Theodore G. Trafton; Evan L. Leventhal

2007-01-01

453

Evaluation of Simultaneous Teaching of Extremities in Gross Anatomy Program.  

ERIC Educational Resources Information Center

|A gross anatomy program was evaluated that shortened the dissection time on the extremities by having half the class dissect either the upper or lower extremity and then study the opposite extremity already dissected by other classmates. Analysis of covariance showed that the program efficiently utilized laboratory time. (MLW)|

Peppler, R . D.; And Others

1985-01-01

454

Brain anatomy and sensorimotor gating in Asperger's syndrome  

Microsoft Academic Search

Summary Asperger's syndrome (an autistic disorder) is character- ized by stereotyped and obsessional behaviours, and pervasive abnormalities in socio-emotional and commu- nicative behaviour. These symptoms lead to social exclusion and a significant healthcare burden; however, their neurobiological basis is poorly understood. There are few studies on brain anatomy of Asperger's syn- drome, and no focal anatomical abnormality has been reliably

Grainne M. McAlonan; Eileen Daly; Veena Kumari; Hugo D. Critchley; Therese van Amelsvoort; John Suckling; Andrew Simmons; Thordur Sigmundsson; Kathyrn Greenwood; Ailsa Russell; Nicole Schmitz; Francesca Happe; Patricia Howlin; Declan G. M. Murphy

2002-01-01

455

Body Painting as a Tool in Clinical Anatomy Teaching  

ERIC Educational Resources Information Center

|The teaching of human anatomy has had to respond to significant changes in medical curricula, and it behooves anatomists to devise alternative strategies to effectively facilitate learning of the discipline by medical students in an integrated, applied, relevant, and contextual framework. In many medical schools, the lack of cadaver dissection as…

McMenamin, Paul G.

2008-01-01

456

MORPHING GENERIC ORGANS TO SPEAKER-SPECIFIC ANATOMIES  

Microsoft Academic Search

We present here a framework for developing a generic talking head capable of reproducing the anatomy and the facial deformations induced by speech movements with only a few parameters. Speech-related facial movements are controlled by six parameters. We characterize the skull and mandible variability by six and seven free parameters respectively. Speaker-specific skull, jaw and face data are normalized using

G. Bailly; M. Chabanas; M. Desvignes; F. Elisei; M. Odisio; Y. Payan

457

Addressing Catastrophic Risks: Disparate Anatomies Require Tailored Therapies  

Microsoft Academic Search

Catastrophic risks differ in terms of their natural or human origins, their possible amplification by human behaviors, and the relationships between those who create the risks and those who suffer the losses. Given their disparate anatomies, catastrophic risks generally require tailored therapies, with each prescribed therapy employing a specific portfolio of policy strategies. Given that catastrophic risks occur rarely, and

W. Kip Viscusi; Richard J. Zeckhauser

2011-01-01

458

Diffusion of Innovations: Smartphones and Wireless Anatomy Learning Resources  

ERIC Educational Resources Information Center

|The author has previously reported on principles of diffusion of innovations, the processes by which new technologies become popularly adopted, specifically in relation to anatomy and education. In presentations on adopting handheld computers [personal digital assistants (PDAs)] and personal media players for health sciences education, particular…

Trelease, Robert B.

2008-01-01

459

The anatomy and pathology of the central auditory pathways.  

PubMed

The anatomy of the central auditory pathways from the cochlear nucleus to the auditory cortex is reviewed. The common pathologies affecting these pathways are described and the neurological, ophthalmological and vestibular symptoms and signs, which are valuable in diagnosing and siting the level of these lesions are discussed. PMID:7011456

Luxon, L M

1981-02-01

460

Anatomy-Based Joint Models for Virtual Human Skeletons  

Microsoft Academic Search

This paper describes a new joint model for articulated human skeletons. The model is based in human anatomy and was conceived for use in medical applications. In this model, we try to overcome some limitations of other models used in computer graphics. To validate, we compared a knee modeled with our approach with a simulator, a plastic model of a

Anderson Maciel; Luciana Porcher Nedel; Carla Maria Dal Sasso Freitas

2002-01-01

461

Design, Implementation, and Evaluation of an Innovative Anatomy Course  

NSDL National Science Digital Library

This article describes the impact of the reformation of a medical school gross anatomy course. Included in the article: A discussion of the reformation, formative and summative assessments evaluating the program and students, and the results of student learning over the four year transformation.

William C Rando (Yale University McDougal Graduate Teaching Center); Dr. Michael O'Brien (Yale University Medical School); MD Andrew Haims (Yale University Medical School); PhD William Stewart (Yale University Anatomy)

2010-04-23

462

Gross heart anatomy of Arctocephalus australis (Zimmerman, 1783)  

Microsoft Academic Search

Little research has been carried out on the gross visceral anatomy of the Otariidae, and the anatomical information for the southern fur seals, Arctocephalus spp., is scant. The aim of the present study was to describe the external and internal conformation, and the sanguineous\\u000a irrigation of the heart of Arctocephalus australis. Twelve hearts of Arctocephalus australis were studied by simple

William Pérez; Helena Katz; Martin Lima

2008-01-01

463

Surgical anatomy of the dural walls of the cavernous sinus  

Microsoft Academic Search

The external structure of each cavernous sinus (CS) is made of four dural walls. The aim of this study was to describe the anatomy of the dural walls of the CS. We studied 42 adult cadaveric heads, fixed with formalin and injected with coloured silicon. The main findings were: (i) the lateral wall of the CS has two layers –

Alvaro Campero; A. Agustin Campero; Carolina Martins; Alexandre Yasuda; Albert L. Rhoton Jr.

2010-01-01

464

Strategic Improvements for Gross Anatomy Web-Based Teaching  

PubMed Central

Current generations of graduate students have been immersed in technology from their early school years and have high expectations regarding digital resources. To better meet the expectations of Gross Anatomy students at our institution, electronic radiology teaching files for first-year coursework were organized into a web site. The web site was custom designed to provide material that directly correlated to the Gross Anatomy dissection and lectures. Quick links provided sets of images grouped by anatomic location. Additionally, Lab and Study Companions provided specific material for the students to review prior to and after lectures and gross dissections. Student opinions of this education resource were compared to student opinions of the prior year's digital teaching files. The new content was ranked as more user?friendly (3.1 points versus 2.3 points) and more useful for learning anatomy (3.3 points versus 2.6 points). Many students reported that using the web portal was critical in helping them to better understand relationships of anatomical structures. These findings suggest that a well-organized web portal can provide a user-friendly, valuable educational resource for medical students who are studying Gross Anatomy.

Marker, David R.; Juluru, Krishna; Long, Chris; Magid, Donna

2012-01-01

465

NCI Funded Research Portfolio - ZIABC010885 Detail  

Cancer.gov

This project is focused on the study of the pathogenesis of HIV-associated malignancies and the development of novel therapies for these tumors based on this understanding. Much of the work on AIDS-related malignancies has focused on tumors associated with Kaposis sarcoma-associated herpesvirus (KSHV), also called human herpesvirus-8 (HHV-8). This virus is the cause of Kaposis sarcoma (KS), primary effusion lymphoma (PEL) and multicentric Castlemans disease (MCD).

466

NCI Funded Research Portfolio - ZIASC010354 Detail  

Cancer.gov

The primary objective of this project is to develop new agents for the treatment of childhood cancers with an emphasis on a more rational, targeted approach of drug development based on the current understanding of the molecular pathogenesis of human cancers. New molecularly targeted agents that are undergoing clinical development for adult cancers will be applied to childhood cancers based on the mechanism of action of the drug and the importance of the target in childhood cancers.

467

NCI Funded Research Portfolio - ZIABC010888 Detail  

Cancer.gov

This project is focused on the clinical study of patients with AIDS-related malignancies. Much of the work is focused on tumors associated with Kaposis sarcoma-associated herpesvirus (KSHV), also called human herpesvirus-8 (HHV-8). This virus is the cause of Kaposis sarcoma (KS), primary effusion lymphoma (PEL) and multicentric Castlemans disease (MCD). We are also studying antibody to VEGF (bevacizumab) as a therapeutic agent in KS as well as BAY 43-9007 (sorafineb).

468

NCI Funded Research Portfolio - ZIASC006737 Detail  

Cancer.gov

During the past year, the Retroviral Diseases Section has conducted research on human immunodeficiency virus (HIV) disease. We have been focusing on the HIV proteaseand the GagPol protease precursor. The first part of the project is exploring the feasibility of developing a novel therapy to HIV protease through inhibition of HIV protease dimerization. HIV protease is a dimer composed of two identical monomers.

469

NCI Funded Research Portfolio - ZIABC010733 Detail  

Cancer.gov

The scope of this project is limited to describing visual characteristics corresponding to various types of pigmented lesions in common, acquired melanocytic nevi and in patients with the rare genetic disease xeroderma pigmentosum. Under the auspices of clinical protocol 06-C-0060 (Thomas J. Hornyak, M.D., Ph.D., Principal Investigator), patients are recruited to the Dermatology Clinic for study and tissue acquisition of melanocytic nevi.

470

Requirements for an on-line knowledge-based anatomy information system.  

PubMed Central

User feedback from the Digital Anatomist Web-based anatomy atlases, together with over 20 years of anatomy teaching experience, were used to formulate the requirements and system design for a next-generation anatomy information system. The main characteristic of this system over current image-based approaches is that it is knowledge-based. A foundational model of anatomy is accessed by an intelligent agent that uses its knowledge about the available anatomy resources and the user types to generate customized interfaces. Current usage statistics suggest that even partial implementation of this design will be of great practical value for both clinical and educational needs. Images Figure 1

Brinkley, J. F.; Rosse, C.

1998-01-01

471

5 a day for better health--nine community research projects to increase fruit and vegetable consumption  

PubMed Central

One of the national objectives in “Healthy People 2000” is for members of the public to increase their consumption of fruits and vegetables to five or more servings daily. The National Cancer Institute (NCI) began a nationwide campaign to achieve this objective in 1991. As part of this campaign, the NCI funded nine research studies in 1993. These projects are implementing and evaluating community-based programs designed to increase fruit and vegetable consumption among different segments of the population in Alabama, Arizona, Georgia, Louisiana, Maryland, Massachusetts, Minnesota, North Carolina, and Washington. The settings for these projects include the Special Supplement Food Program for Women, Infants, and Children (WIC Programs), churches, worksites, and schools. The projects are led by multidisciplinary teams and entail extensive collaboration among academic, governmental, private sector, and voluntary agencies within each State. The projects represent a model public health paradigm for conducting this type of research.

Havas, Stephen; Heimendinger, Jerianne; Damron, Dorothy; Nicklas, Theresa A.; Cowan, Arnette; Beresford, Shirley A. A.; Sorensen, Glorian; Buller, David; Bishop, Donald; Baranowski, Tom; Reynolds, Kim

1995-01-01

472

Anatomy of brain-stem white-matter tracts shown by diffusion-weighted imaging.  

PubMed

We acquired high-resolution MRI and anisotropically diffusion-weighted images (DWI) with direction-selective gradients of the brain stem in 20 healthy volunteers, to identify brain-stem structures such as white-matter tracts and nuclei which show diffusion anisotropy. After averaging and superposition of individual cuts, the images were projected onto appropriate plates of the Schaltenbrand and Wahren anatomical atlas. We identified 20 structures--white-matter tracts and some nuclei--with high contrast. The direction of fibres could be determined as areas of increased (parallel to) or decreased diffusion (perpendicular to the gradient). This study may contribute to understanding of the functional anatomy of the brain stem. PMID:11760801

Fitzek, C; Weissmann, M; Speckter, H; Fitzek, S; Hopf, H C; Schulte, E; Stoeter, P

2001-11-01

473

The anatomy of acute scaphoid fractures: a three-dimensional analysis of patterns.  

PubMed

Various classifications of scaphoid fractures have been based on plain radiography, but there are difficulties in defining the actual fracture line without an appreciation of the three-dimensional anatomy. Radiological fracture lines were therefore mapped on transparent methylmethacrylate models of the bone. An analysis of 91 acute fractures showed that 11 were apparently incomplete. The other 80 showed three basic anatomical patterns: transverse through the waist, oblique in the plane of the dorsal sulcus, or of the proximal pole. There was some variation and comminution in these patterns, but no distal fractures of the body were seen. The interpretation of different radiological projections is discussed. The findings have implications for the management and the assessment of outcome. PMID:9546447

Compson, J P

1998-03-01

474

Incorporating Radiology into Medical Gross Anatomy: Does the Use of Cadaver CT Scans Improve Students' Academic Performance in Anatomy?  

ERIC Educational Resources Information Center

|Radiological images show anatomical structures in multiple planes and may be effective for teaching anatomical spatial relationships, something that students often find difficult to master. This study tests the hypotheses that (1) the use of cadaveric computed tomography (CT) scans in the anatomy laboratory is positively associated with…

Lufler, Rebecca S.; Zumwalt, Ann C.; Romney, Carla A.; Hoagland, Todd M.

2010-01-01

475

Anatomy in the Third Reich: an outline, part 2. Bodies for anatomy and related medical disciplines.  

PubMed

All anatomical departments of German universities used bodies of the executed and other victims of the National Socialist (NS) regime for their work. Many of these victims had been executed in prisons and were members of the German political opposition; others had perished in camps for prisoners of war or forced laborers and concentration camps, and were of various European and other descent. Anatomists generally welcomed the increased influx of "fresh material" for purposes of research and education of the growing numbers of medical students. No anatomist is known to have refused work with the bodies of NS victims. Other medical disciplines also made use of these bodies, among them were racial hygienists and neuropathologists. In the late 19th and early 20th century, the fields of anatomy, physical anthropology, and racial hygiene (eugenics) were closely related in their subject matter. Anatomists were involved in the biological foundation of racial hygiene, most prominently among them Eugen Fischer. The discipline was established as part of the medical curriculum after 1920. Racial hygiene became the scientific justification for NS policies that led to racial discrimination, involuntary sterilization and ultimately mass murder. Anatomists taught racial hygiene throughout the Third Reich and did research in this area. Some were actively involved in NS policies through propaganda and evaluations for the so-called Genetic Health Courts, whereas others became victims of their own science in that they were dismissed for racial reasons. PMID:19852054

Hildebrandt, S

2009-11-01

476

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set  

PubMed Central

The panel of 60 human cancer cell lines (the NCI-60) assembled by the National Cancer Institute for anticancer drug discovery is a widely used resource. The NCI-60 has been characterized pharmacologically and at the molecular level more extensively than any other set of cell lines. However, no systematic mutation analysis of genes causally implicated in oncogenesis has been reported. This study reports the sequence analysis of 24 known cancer genes in the NCI-60 and an assessment of 4 of the 24 genes for homozygous deletions. One hundred thirty-seven oncogenic mutations were identified in 14 (APC, BRAF, CDKN2, CTNNB1, HRAS, KRAS, NRAS, SMAD4, PIK3CA, PTEN, RB1, STK11, TP53, and VHL) of the 24 genes. All lines have at least one mutation among the cancer genes examined, with most lines (73%) having more than one. Identification of those cancer genes mutated in the NCI-60, in combination with pharmacologic and molecular profiles of the cells, will allow for more informed interpretation of anticancer agent screening and will enhance the use of the NCI-60 cell lines for molecularly targeted screens.

Ikediobi, Ogechi N.; Davies, Helen; Bignell, Graham; Edkins, Sarah; Stevens, Claire; O'Meara, Sarah; Santarius, Thomas; Avis, Tim; Barthorpe, Syd; Brackenbury, Lisa; Buck, Gemma; Butler, Adam; Clements, Jody; Cole, Jennifer; Dicks, Ed; Forbes, Simon; Gray, Kristian; Halliday, Kelly; Harrison, Rachel; Hills, Katy; Hinton, Jonathan; Hunter, Chris; Jenkinson, Andy; Jones, David; Kosmidou, Vivienne; Lugg, Richard; Menzies, Andrew; Mironenko, Tatiana; Parker, Adrian; Perry, Janet; Raine, Keiran; Richardson, David; Shepherd, Rebecca; Small, Alex; Smith, Raffaella; Solomon, Helen; Stephens, Philip; Teague, Jon; Tofts, Calli; Varian, Jennifer; Webb, Tony; West, Sofie; Widaa, Sara; Yates, Andy; Reinhold, William; Weinstein, John N.; Stratton, Michael R.; Futreal, P. Andrew; Wooster, Richard

2009-01-01

477

NCI-H716 cells as a model for endocrine differentiation in colorectal cancer.  

PubMed

In colonic neoplasms, endocrine differentiation is encountered not only in carcinoid tumors but also in adenocarcinomas, where endocrine cells may represent a distinct line of differentiation in the tumor. The significance of endocrine differentiation in colorectal cancer is not well established, partly because of the paucity of tumor cell lines which can serve as a model for studying endocrine differentiation. In this report we describe the properties of NCI-H716 cells, a cell line derived from a poorly differentiated adenocarcinoma of the caecum, under various in vitro conditions and as xenografts in athymic mice. Phenotypical properties were immunohistochemically assessed using a panel of differentiation related antibodies, and also by Northern blot analysis and by electron microscopy. Receptors for biogenic amines and peptide hormones were analyzed by ligand binding assay. These studies show that: 1. NCI-H716 cells can be undifferentiated, or show endocrine, mucin-producing or "amphicrine" properties. 2. Endocrine differentiation of NCI-H716 cells preferentially occurs in xenografts in athymic mice, which suggests that mesenchymal elements induce endocrine differentiation. 3. NCI-H716 cells express large amounts of high affinity receptors for gastrin, serotonin and somatostatin and these substances can regulate growth. Thus, NCI-H716 cells form a suitable model for the study of endocrine differentiation in intestinal epithelium and of auto- or paracrine growth regulation in intestinal neoplasia. PMID:1359704

de Bruïne, A P; Dinjens, W N; Pijls, M M; vd Linden, E P; Rousch, M J; Moerkerk, P T; de Goeij, A F; Bosman, F T

1992-01-01

478

Aberrant regulation of human intestinal proglucagon gene expression in the NCI-H716 cell line.  

PubMed

Despite interest in understanding glucagon-like peptide-1 (GLP-1) production, the factors important for GLP-1 biosynthesis remain poorly understood. We examined control of human proglucagon gene expression in NCI-H716 cells, a cell line that secretes GLP-1 in a regulated manner. Insulin, phorbol myristate acetate, or forskolin, known regulators of rodent proglucagon gene expression, had no effect, whereas sodium butyrate decreased levels of NCI-H716 proglucagon mRNA transcripts. The inhibitory effect of sodium butyrate was mimicked by trichostatin A but was not detected with sodium acetate or isobutyrate. The actions of butyrate were not diminished by the ERK1/2 inhibitor PD98059, p38 inhibitor SB203580, or soluble guanylate cyclase inhibitor LY83583 or following treatment of cells with KT5823, a selective inhibitor of cGMP-dependent protein kinase. NCI-H716 cells expressed multiple proglucagon gene transcription factors including isl-1, pax-6, pax-2, cdx-2/3, pax-4, hepatocyte nuclear factor (HNF)-3 alpha, HNF-3beta, HNF-3 gamma, and Nkx2.2. Nevertheless, the butyrate-dependent inhibition of proglucagon gene expression was not associated with coordinate changes in transcription factor expression and both the human and rat transfected proglucagon promoters were transcriptionally inactive in NCI-H716 cells. Hence, NCI-H716 cells may not be a physiologically optimal model for studies of human enteroendocrine proglucagon gene transcription. PMID:12697711

Cao, Xiemin; Flock, Grace; Choi, Caroline; Irwin, David M; Drucker, Daniel J

2003-05-01

479

The Anatomy of Teleneurosurgery in China  

PubMed Central

With its huge population and vast territory, China faces a great challenge in providing modern advanced health care services to all parts of the country. The advances of information communication technologies (ICTs) and the advent of internet have revolutionised the means in the delivery of healthcare via telemedicine to remote and underserved populations, which to a certain extent has been very well exploited in China, especially where 70% peasants residing in the rural areas. This paper reviews the latest development in telemedicine infrastructure in China with the focus on the development of teleneurosurgery, drawing from the results gained from a 3-year networking project between Europe and China on telemedicine (TIME, 2005–2007) funded by European Commission under Asia ICT programme, with an aim to shape up envisages of future medical care in China. Comparison with its counterparts in Europe is also addressed.

Gao, Xiaohong

2011-01-01

480

Resemblance of Tongue Anatomy in Twins  

PubMed Central

This study compared the anatomical features of the tongue in nine pairs of twins — six monozygotic and three dizygotic. The aim of the project was to determine if tongues, like any other anatomical structure, could be used to reliably predict relatedness given that tongue shape, presentation and surface can be influenced by environment. Using the method of forced choice, 30 subjects were asked to match the photographs of tongues from twins. Our data indicate that, based on visual assessment, monozygotic twins have highly similar tongues (60% matches); similarly, dizygotic twins were matched 31% of the time, which is a higher probability than would be expected from random selection. This study should help identify baseline and control data in future behavioral studies of taste, which has a genetic basis.

Spielman, Andrew I.; Brand, Joseph G.; Buischi, Yvonne; Bretz, Walter A.

2011-01-01

481

Resemblance of tongue anatomy in twins.  

PubMed

This study compared the anatomical features of the tongue in nine pairs of twins - six monozygotic and three dizygotic. The aim of the project was to determine if tongues, like any other anatomical structure, could be used to reliably predict relatedness given that tongue shape, presentation and surface can be influenced by environment. Using the method of forced choice, 30 subjects were asked to match the photographs of tongues from twins. Our data indicate that, based on visual assessment, monozygotic twins have highly similar tongues (60% matches); similarly, dizygotic twins were matched 31% of the time, which is a higher probability than would be expected from random selection. This study should help identify baseline and control data in future behavioral studies of taste, which has a genetic basis. PMID:21623658

Spielman, Andrew I; Brand, Joseph G; Buischi, Yvonne; Bretz, Walter A

2011-06-01

482

The anatomy of teleneurosurgery in china.  

PubMed

With its huge population and vast territory, China faces a great challenge in providing modern advanced health care services to all parts of the country. The advances of information communication technologies (ICTs) and the advent of internet have revolutionised the means in the delivery of healthcare via telemedicine to remote and underserved populations, which to a certain extent has been very well exploited in China, especially where 70% peasants residing in the rural areas. This paper reviews the latest development in telemedicine infrastructure in China with the focus on the development of teleneurosurgery, drawing from the results gained from a 3-year networking project between Europe and China on telemedicine (TIME, 2005-2007) funded by European Commission under Asia ICT programme, with an aim to shape up envisages of future medical care in China. Comparison with its counterparts in Europe is also addressed. PMID:21941536

Gao, Xiaohong

2011-09-20

483

Surgical anatomy of the cribriform plate and adjacent areas.  

PubMed

Continuous improvement of surgical techniques is needed in skull base surgery in order to decrease intraoperative complications during various operations. However, the basis of minimizing damage in the operative field is a comprehensive knowledge of microsurgical anatomy. This article provides a detailed description of the cribriform plate and adjacent areas, based on investigations of over one thousand dried skulls and 225 computerized tomography scans of the anterior skull base. The main anatomic structures and the different types of the cribriform plate are demonstrated on color photographs and identified on CT scans as well. The variations important in anterior skull base approaches are also discussed and compared with the data found in the literature. The surface anatomy and development of the cribriform plate is described. PMID:15747213

Vasvári, G; Reisch, R; Patonay, L

2005-02-01

484

GateWay Community College: Anatomy & Physiology Tutorials  

NSDL National Science Digital Library

These great anatomy and physiology tutorials were developed by Dr. James Crimando, Chair of the Math and Science Division at GateWay Community College. The interactive tutorials utilize excellent images and illustrations to educate students and others about various regions of the body including the skull, muscles, vertebrae, hand, thyroid gland, and more. Site users are able to explore different views of these corporeal regions such as a lateral view of the lumbar vertebra; interior view of the skull; the posterior view of the heart, and parasaggital views of a sheep brain. Many of the tutorials also allow users to test their anatomical knowledge with interactive quizzes. Note: To reach the tutorials simply select the Anatomy & Physiology Tutorials hyperlink listed in the menu on the left side of the Biological Sciences HomePage.

485

Anatomy in ancient India: a focus on the Susruta Samhita  

PubMed Central

This review focuses on how the study of anatomy in India has evolved through the centuries. Anatomical knowledge in ancient India was derived principally from animal sacrifice, chance observations of improperly buried human bodies, and examinations of patients made by doctors during treatment. The Vedic philosophies form the basis of the Ayurvedic tradition, which is considered to be one of the oldest known systems of medicine. Two sets of texts form the foundation of Ayurvedic medicine, the Susruta Samhita and the Charaka Samhita. The Susruta Samhita provided important surgical and anatomical information of the understanding of anatomy by Indians in the 6th century BCE. Here we review the anatomical knowledge known to this society.

Loukas, Marios; Lanteri, Alexis; Ferrauiola, Julie; Tubbs, R Shane; Maharaja, Goppi; Shoja, Mohammadali Mohajel; Yadav, Abhishek; Rao, Vishnu Chellapilla

2010-01-01

486

Aligning Representations of Anatomy using Lexical and Structural Methods  

PubMed Central

Objective The objective of this experiment is to develop methods for aligning two representations of anatomy (the Foundational Model of Anatomy and GALEN) at the lexical and structural level. Methods The alignment consists of the following four steps: 1) acquiring terms, 2) identifying anchors (i.e., shared concepts) lexically, 3) acquiring explicit and implicit semantic relations, and 4) identifying anchors structurally. Results 2,353 anchors were identified by lexical methods, of which 91% were supported by structural evidence. No evidence was found for 7.5% of the anchors and 1.5% received negative evidence. Discussion The importance of taking advantage of implicit domain knowledge acquired through complementation, augmentation, and inference is discussed.

Zhang, Songmao; Bodenreider, Olivier

2003-01-01

487

Anatomy in ancient India: a focus on the Susruta Samhita.  

PubMed

This review focuses on how the study of anatomy in India has evolved through the centuries. Anatomical knowledge in ancient India was derived principally from animal sacrifice, chance observations of improperly buried human bodies, and examinations of patients made by doctors during treatment. The Vedic philosophies form the basis of the Ayurvedic tradition, which is considered to be one of the oldest known systems of medicine. Two sets of texts form the foundation of Ayurvedic medicine, the Susruta Samhita and the Charaka Samhita. The Susruta Samhita provided important surgical and anatomical information of the understanding of anatomy by Indians in the 6th century BCE. Here we review the anatomical knowledge known to this society. PMID:20887391

Loukas, Marios; Lanteri, Alexis; Ferrauiola, Julie; Tubbs, R Shane; Maharaja, Goppi; Shoja, Mohammadali Mohajel; Yadav, Abhishek; Rao, Vishnu Chellapilla

2010-09-30

488

A review of anatomy education in Australasian medical schools  

Microsoft Academic Search

Changes to medical education in Australia include a proliferation of medical schools, shorter courses, shifts toward problem-based learning, and large-scale medical knowledge expansion. Students also spend less time on university campuses and more time at clinical teaching sites which are often non-specialised, regional and remote from the parent university. These changes leave little room for teaching anatomy as a pure

Noel Tait; Steven J. Craig; Darryl J. McAndrew; Christos Georgiou

2009-01-01

489

How useful is YouTube in learning heart anatomy?  

PubMed

Nowadays more and more modern medical degree programs focus on self-directed and problem-based learning. That requires students to search for high quality and easy to retrieve online resources. YouTube is an emerging platform for learning human anatomy due to easy access and being a free service. The purpose of this study is to make a quantitative and qualitative analysis of the available human heart anatomy videos on YouTube. Using the search engine of the platform we searched for relevant videos using various keywords. Videos with irrelevant content, animal tissue, non-English language, no sound, duplicates, and physiology focused were excluded from further elaboration. The initial search retrieved 55,525 videos, whereas only 294 qualified for further analysis. A unique scoring system was used to assess the anatomical quality and details, general quality, and the general data for each video. Our results indicate that the human heart anatomy videos available on YouTube conveyed our anatomical criteria poorly, whereas the general quality scoring found borderline. Students should be selective when looking up on public video databases as it can prove challenging, time consuming, and the anatomical information may be misleading due to absence of content review. Anatomists and institutions are encouraged to prepare and endorse good quality material and make them available online for the students. The scoring rubric used in the study comprises a valuable tool to faculty members for quality evaluation of heart anatomy videos available on social media platforms. Anat Sci Educ. © 2013 American Association of Anatomists. PMID:23564745

Raikos, Athanasios; Waidyasekara, Pasan

2013-04-01

490

Anatomy of a disruption in MTX (Microwave Tokamak Experiment)  

SciTech Connect

Disruptions are observed in the Microwave Tokamak Experiment, MTX (nee Alcator C), over a wide range of plasma parameters. Indeed, disruptions often occur far from the boundaries of the operating space as defined by Hugill and l{sub i}-q plots. Despite this, the general behavior during the disruptive process is generally similar whatever the operating parameters. This report will describe one disruption in detail in order to provide a detailed anatomy of the event.

Hooper, E.B.; Casper, T.A.; Lasnier, C.J.; Makowski, M.A.; Meyer, W.H.; Moller, J.M.; Oasa, K.; Rice, B.W.; Wood, R.D.

1990-10-15

491

Teaching the Anatomy of a Scientific Journal Article  

NSDL National Science Digital Library

To promote inquiry-based learning, the authors integrate the anatomy of a scientific journal article into their secondary science curriculum. In this article, they present three classroom activities used to teach students about the function and format of scientific journal articles. The first focuses on journal article figures, the second on journal abstracts, and in the third, students produce their own journal articles, which are based on their investigations.

Busch, Allison K.; Schinske, Jeffrey N.; Clayman, Karen; Tanner, Kimberly D.

2008-10-01

492

Consequences of Scapular Anatomy for Reversed Total Shoulder Arthroplasty  

Microsoft Academic Search

The reverse total shoulder prosthesis provides successful functional outcome in many patients with rotator cuff tear arthropathy.\\u000a However, scapular notching, a direct consequence of mechanical impingement between the humeral prosthesis and the glenoid,\\u000a remains a major concern. We presumed a better knowledge of the anatomy of the scapula would enable design or placement modifications\\u000a to minimize this phenomenon. After establishing

Bart Middernacht; Pieter-Jan De Roo; Georges Van Maele; Lieven F. De Wilde

2008-01-01

493

Polymorphism and vestigiality: comparative anatomy and morphology of bryozoan avicularia  

Microsoft Academic Search

Avicularia are polymorphic zooids characteristic of cheilostome bryozoans. Avicularia are assumed to have a defensive role\\u000a yet ascertaining the presence of sensory structures to support this theory has been overlooked. We examine palatal morphology\\u000a of the avicularia from five species of cheilostome bryozoans and compare the ultrastructural anatomy of the avicularia from\\u000a two bugulid species from different habitats. SEM analysis

Michelle C. Carter; Dennis P. Gordon; Jonathan P. A. Gardner

2010-01-01

494

Fish Anatomy: A Comparison Between Temperate and Antarctic Fishes  

NSDL National Science Digital Library

In this activity, students will dissect a fish purchased from a fish market to study its external and internal anatomy. They will observe its gills, kidney, and blood through a microscope and take a variety of measurements of many of the internal organs. They will practice their observation skills by making accurate illustrations. These data and drawings will then be compared with some Antarctic fishes from the family Notothenidae in order to direct a discussion on morphological adaptations for survival in polar seas.

Atwood, Frederick

495

Computational anatomy in the study of bone structure.  

PubMed

Osteoporosis is a major public health threat for millions of Americans with billions of dollars per year of national direct costs for osteoporotic fractures. Osteoporosis results in a decrease in overall bone mass and subsequent increase in the risk of bone fracture. Bone strength arises from the combination of bone size and shape, the distribution of bone mass throughout the structure, and the quality of the bone material. Advances in medical imaging have enabled a comprehensive assessment of bone structure through the analysis of high-resolution scans of relevant anatomical sites, eg, the proximal femur. However, conventional imaging analysis techniques use predefined regions of interest that do not take full advantage of such scans. Recently, computational anatomy, a set of imaging-based analysis algorithms, has emerged as a promising technique in studies of osteoporosis. Computational anatomy enables analyses that are not biased to one particular region and provide a more complete assessment of the whole structure. In this article, we review studies that have used computational anatomy to investigate the structure of the proximal femur in relation to age, fracture, osteoporotic treatment, and spaceflight effects. PMID:23722733

Carballido-Gamio, Julio; Nicolella, Daniel P

2013-09-01

496

A Unified Anatomy Ontology of the Vertebrate Skeletal System  

PubMed Central

The skeleton is of fundamental importance in research in comparative vertebrate morphology, paleontology, biomechanics, developmental biology, and systematics. Motivated by research questions that require computational access to and comparative reasoning across the diverse skeletal phenotypes of vertebrates, we developed a module of anatomical concepts for the skeletal system, the Vertebrate Skeletal Anatomy Ontology (VSAO), to accommodate and unify the existing skeletal terminologies for the species-specific (mouse, the frog Xenopus, zebrafish) and multispecies (teleost, amphibian) vertebrate anatomy ontologies. Previous differences between these terminologies prevented even simple queries across databases pertaining to vertebrate morphology. This module of upper-level and specific skeletal terms currently includes 223 defined terms and 179 synonyms that integrate skeletal cells, tissues, biological processes, organs (skeletal elements such as bones and cartilages), and subdivisions of the skeletal system. The VSAO is designed to integrate with other ontologies, including the Common Anatomy Reference Ontology (CARO), Gene Ontology (GO), Uberon, and Cell Ontology (CL), and it is freely available to the community to be updated with additional terms required for research. Its structure accommodates anatomical variation among vertebrate species in development, structure, and composition. Annotation of diverse vertebrate phenotypes with this ontology will enable novel inquiries across the full spectrum of phenotypic diversity.

Dahdul, Wasila M.; Balhoff, James P.; Blackburn, David C.; Diehl, Alexander D.; Haendel, Melissa A.; Hall, Brian K.; Lapp, Hilmar; Lundberg, John G.; Mungall, Christopher J.; Ringwald, Martin; Segerdell, Erik; Van Slyke, Ceri E.; Vickaryous, Matthew K.; Westerfield, Monte; Mabee, Paula M.

2012-01-01

497

Inside out: modern imaging techniques to reveal animal anatomy.  

PubMed

Animal anatomy has traditionally relied on detailed dissections to produce anatomical illustrations, but modern imaging modalities, such as MRI and CT, now represent an enormous resource that allows for fast non-invasive visualizations of animal anatomy in living animals. These modalities also allow for creation of three-dimensional representations that can be of considerable value in the dissemination of anatomical studies. In this methodological review, we present our experiences using MRI, CT and ?CT to create advanced representation of animal anatomy, including bones, inner organs and blood vessels in a variety of animals, including fish, amphibians, reptiles, mammals, and spiders. The images have a similar quality to most traditional anatomical drawings and are presented together with interactive movies of the anatomical structures, where the object can be viewed from different angles. Given that clinical scanners found in the majority of larger hospitals are fully suitable for these purposes, we encourage biologists to take advantage of these imaging techniques in creation of three-dimensional graphical representations of internal structures. PMID:21445356

Lauridsen, Henrik; Hansen, Kasper; Wang, Tobias; Agger, Peter; Andersen, Jonas L; Knudsen, Peter S; Rasmussen, Anne S; Uhrenholt, Lars; Pedersen, Michael

2011-03-22

498

Anatomy "steeplechase" online: necessity sometimes is the catalyst for innovation.  

PubMed

In most medical schools, summative practical examination in Anatomy usually takes the format of a "steeplechase" ("spotters" or "bell ringers") conducted in the gross anatomy laboratory using cadaveric material and prosected specimens. Recently, we have started to administer similar examinations online using the quiz facility in WebCT™ and Moodle™. This article chronicles how we conceived and developed this method within the peculiar nature of our medical school setting. Over a five year period, practical summative examinations were organized as "steeplechase" online. The online examinations were administered using WebCT™ and later Moodle™ learning management software. Assessment "objects" were created from the materials available for anatomy teaching. These were digital images of cadaveric materials, radiological, and prosected specimens. In addition, short video clips of 30 seconds duration demonstrating muscle action were produced. These objects were optimized for online viewing and then uploaded onto the learning management software. A bank of questions (multiple choice or short answer type) was then created and linked to the assessment objects. These were used in place of the steeplechase in the computer laboratory. This method serves a crucial purpose in places like ours where continuous availability of human cadavers is impossible. Although time consuming initially, once questions are setup online, future retrieval, and administration becomes convenient especially where there are large batches of students. In addition, the online environment offers distinct advantages with regards to image quality, psychometric analysis of the examination and reduction of staff preparation time compared to traditional "steeplechase." PMID:21438159

Inuwa, Ibrahim Muhammad; Al Rawahy, Maimouna; Taranikanti, Varna; Habbal, Omar

2010-12-02

499

A unified anatomy ontology of the vertebrate skeletal system.  

PubMed

The skeleton is of fundamental importance in research in comparative vertebrate morphology, paleontology, biomechanics, developmental biology, and systematics. Motivated by research questions that require computational access to and comparative reasoning across the diverse skeletal phenotypes of vertebrates, we developed a module of anatomical concepts for the skeletal system, the Vertebrate Skeletal Anatomy Ontology (VSAO), to accommodate and unify the existing skeletal terminologies for the species-specific (mouse, the frog Xenopus, zebrafish) and multispecies (teleost, amphibian) vertebrate anatomy ontologies. Previous differences between these terminologies prevented even simple queries across databases pertaining to vertebrate morphology. This module of upper-level and specific skeletal terms currently includes 223 defined terms and 179 synonyms that integrate skeletal cells, tissues, biological processes, organs (skeletal elements such as bones and cartilages), and subdivisions of the skeletal system. The VSAO is designed to integrate with other ontologies, including the Common Anatomy Reference Ontology (CARO), Gene Ontology (GO), Uberon, and Cell Ontology (CL), and it is freely available to the community to be updated with additional terms required for research. Its structure accommodates anatomical variation among vertebrate species in development, structure, and composition. Annotation of diverse vertebrate phenotypes with this ontology will enable novel inquiries across the full spectrum of phenotypic diversity. PMID:23251424

Dahdul, Wasila M; Balhoff, James P; Blackburn, David C; Diehl, Alexander D; Haendel, Melissa A; Hall, Brian K; Lapp, Hilmar; Lundberg, John G; Mungall, Christopher J; Ringwald, Martin; Segerdell, Erik; Van Slyke, Ceri E; Vickaryous, Matthew K; Westerfield, Monte; Mabee, Paula M

2012-12-10

500

Anatomy and Physiology of the Auditory System  

Microsoft Academic Search

\\u000a \\u000a \\u000a \\u000a \\u000a 1. \\u000a \\u000a The auditory system consists of four anatomically separate structures:\\u000a \\u000a \\u000a \\u000a (a) \\u000a \\u000a those that conduct the stimulus to the receptors\\u000a \\u000a \\u000a \\u000a (b) \\u000a \\u000a the receptors\\u000a \\u000a \\u000a \\u000a (c) \\u000a \\u000a the auditory nerve\\u000a \\u000a \\u000a \\u000a (d) \\u000a \\u000a the central auditory nervous system\\u000a \\u000a \\u000a \\u000a \\u000a \\u000a \\u000a \\u000a \\u000a 2. \\u000a \\u000a The most important part regarding tinnitus is the auditory nervous system.\\u000a \\u000a \\u000a \\u000a 3. \\u000a \\u000a The auditory nervous system consists of two parallel ascending pathways that project to auditory cortices

Aage R. Møller