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Sample records for anatomy project nci

  1. NCI Cohort Consortium Projects

    Cancer.gov

    The African American BMI and Mortality Pooling Project, established in 2011, examines the relation between BMI and disease mortality, including cancer and cardiovascular disease, in African American men and women. The project draws data from seven cohorts that contain at least 10,000 African American participants.

  2. Cancer Genome Anatomy Project | Office of Cancer Genomics

    Cancer.gov

    The National Cancer Institute (NCI) Cancer Genome Anatomy Project (CGAP) is an online resource designed to provide the research community access to biological tissue characterization data. Request a free copy of the CGAP Website Virtual Tour CD from ocg@mail.nih.gov.

  3. Working Group Rosters: NCI Concise Informed Consent Template Project

    Cancer.gov

    Page of 6Working Group Rosters: NCI Concise Informed Consent Template Project Role Working Group 1 (Beginning of template Ė background, required tests, intervention sections) Working Group 2 (Risks and benefits sections) Working Group 3 (Alternatives,

  4. The NCI Digital Divide Pilot Projects: implications for cancer education.

    PubMed

    Kreps, Gary L; Gustafson, David; Salovey, Peter; Perocchia, Rosemarie Slevin; Wilbright, Wayne; Bright, Mary Anne; Muha, Cathy

    2007-01-01

    The National Cancer Institute (NCI) supported four innovative demonstration research projects, "The Digital Divide Pilot Projects," to test new strategies for disseminating health information via computer to vulnerable consumers. These projects involved active research collaborations between the NCI's Cancer Information Service (CIS) and regional cancer control researchers to field test new approaches for enhancing cancer communication in vulnerable communities. The projects were able to use computers to successfully disseminate relevant cancer information to vulnerable populations. These demonstration research projects suggested effective new strategies for using communication technologies to educate underserved populations about cancer prevention, control, and care. PMID:17572002

  5. Life After Risk Models: An NCI Project to Develop a Web Site to Educate Cancer Information Seekers about Cancer Risk Concepts

    Cancer.gov

    Felicia M. Solomon, MPH, OESI, NCI; Margo Michaels, MPH, OESI, NCI; and Maria Sgambati, MD, DCEG, NCI, Jalaima Graham, MPH, Childrenís National Medical Center, Department of Dentistry Life After Risk Models: An NCI Project to Develop a Web Site to

  6. Design Projects in Human Anatomy & Physiology

    ERIC Educational Resources Information Center

    Polizzotto, Kristin; Ortiz, Mary T.

    2008-01-01

    Very often, some type of writing assignment is required in college entry-level Human Anatomy and Physiology courses. This assignment can be anything from an essay to a research paper on the literature, focusing on a faculty-approved topic of interest to the student. As educators who teach Human Anatomy and Physiology at an urban community college,Ö

  7. Design Projects in Human Anatomy & Physiology

    ERIC Educational Resources Information Center

    Polizzotto, Kristin; Ortiz, Mary T.

    2008-01-01

    Very often, some type of writing assignment is required in college entry-level Human Anatomy and Physiology courses. This assignment can be anything from an essay to a research paper on the literature, focusing on a faculty-approved topic of interest to the student. As educators who teach Human Anatomy and Physiology at an urban community college,…

  8. RAS Projects at the NCI Frederick National Lab

    Cancer.gov

    The RAS Initiative involves a number of projects focusing on ways to inhibit the proliferation of cancer cells by mutant RAS proteins. Projects are conducted at the FNLCR hub, with collaboration from the research community nationwide.

  9. Anatomy External [Sahuarita High School Career Curriculum Project].

    ERIC Educational Resources Information Center

    Esser, Robert

    This course entitled "Anatomy External" is concerned with the dissection of the fetal pig, and is one of a series of instructional guides prepared by the teachers for the Sahuarita High School (Arizona) Career Curriculum Project. It consists of five units of study, and 13 behavioral objectives relating to these units are stated. The topics covered…

  10. Anatomy of the Chaco cryogenic project

    SciTech Connect

    Milios, P.B.; Harris, R.A.

    1997-12-31

    In the first quarter of 1996 El Paso Field Services (EPFS) began operation of a new Chaco liquids extraction plant. The plant, located in northwest New Mexico, has the capacity to extract more natural gas liquids (NGL) than any other turboexpander plant in the lower 48 states; 50,000 b/d of NGL from 600 MMscfd of gas. Its existence is the result of El Paso`s desire to combine state-of-the-art processing with processing rates that align EPFS`s interests with the interests of the producers, in order to secure a long term competitive position in the San Juan Basin. All the project stakeholders, the producers, the liquids transporter, the construction contractor, and the processor have benefited from the project. Without regulatory reform the project would not have happened.

  11. Using Independent Research Projects to Foster Learning in the Comparative Vertebrate Anatomy Laboratory

    ERIC Educational Resources Information Center

    Ghedotti, Michael J.; Fielitz, Christopher; Leonard, Daniel J.

    2005-01-01

    This paper presents a teaching methodology involving an independent research project component for use in undergraduate Comparative Vertebrate Anatomy laboratory courses. The proposed project introduces cooperative, active learning in a research context to comparative vertebrate anatomy. This project involves pairs or groups of three students…

  12. NCI Organization

    Cancer.gov

    As the nation's leading federal agency for cancer research, NCI has 30 divisions, offices, and centers who work together to build, maintain, and enhance a cohesive and comprehensive cancer research agenda.

  13. NCI Designated Cancer Centers

    MedlinePLUS

    ... Currents Blog Research Findings Drug Approvals Precision Medicine Leadership Views 2017 Annual Plan & Budget Proposal All Press ... NCI NCI Overview History Contributing to Cancer Research Leadership Director's Page Previous NCI Directors NCI Organization Advisory ...

  14. NCI Grants Management

    Cancer.gov

    The Office of Grants Administration (OGA) is the principal office at NCI †that manages all NCI business-related activities associated with the negotiation, award, and administration of NCI grants and cooperative agreements to help financially support

  15. NCI CAM Events-OCCAM

    Cancer.gov

    Contact Us | Sitemap CAM at the NCI NCI CAM History Highlights of NCI CAM Activities NCI CAM Annual Report Research Funding Opportunities Grant Application Information Research Resources Funded Research Research Results Training Opportunities FAQ's

  16. NCI at a Glance Infographic (Infographic)

    Cancer.gov

    This infographic provides a high-level overview of NCI's historical milestones, funding process, the NCI-designated cancer centers, and training numbers for fiscal year (FY) 2013. The work we do includes genomics, public health, clinical trials, surveillance, scientific review, basic research, funding, drug development, cancer research, survivorship research, and more. Funds available to the NCI in FY 2013 totaled $4.789 billion (not including projects awarded with Stamp Out Breast Cancer funds or royalty income) which reflects a decrease of 5.5 percent or $278 million from the previous fiscal year. In FY 2013, NCI supported 3,590 emerging cancer researchers through training and career development grants and intramural research experiences (not including students and postdoctoral fellows supported by NCI research project grants, cancer center grants, and other non-training mechanisms). http://www.cancer.gov/PublishedContent/Longdesc/longdesc-881829.html

  17. Emergency Preparedness at NCI

    Cancer.gov

    Information to help prepare for an emergency. Includes resources for patients and health care providers to continue cancer care, NCI contacts for grantees, and resources to prepare and update NCI employees and contractors.

  18. NCI Drug Development Collaborative

    Cancer.gov

    CAPR NCI Center for Advanced Preclinical Research-CCR CBC Chemical Biology Consortium CCR Center for Cancer Research-NCI CDA Confidential Disclosure Agreement CRADA Cooperative Research and Development Agreement CSBF Chemical and Structural Biology Facult

  19. NCI Grant Resources Room

    Cancer.gov

    If you’re interested in information about NCI grants, visit the Grant Resources Room. You can talk to NCI staff about grant application and review processes, and even schedule a one-on-one consultation.

  20. Nasal Anatomy

    MedlinePLUS

    ... Statement FIND A DOCTOR RESOURCES Medical Societies Patient Education About this Website Font Size + - Home > ANATOMY > Nasal Anatomy Nasal Anatomy Sinus Anatomy Nasal Physiology Nasal Endoscopy Skull Base Anatomy Virtual Anatomy Disclosure Statement Printer Friendly Nasal Anatomy Justin ...

  1. NCI DEA - NCI Notices Related to Initiatives

    Cancer.gov

    National Institutes of Health, National Cancer Institute, Division of Extramural Activities - Home Page Skip to Main Content Home Funding Advisory Consumer Guides FAQs & Glossary Awarded Research Division of Extramural Activities NCI Notices Related

  2. Relationship of creative projects in anatomy to medical student professionalism, test performance and stress: an exploratory study

    PubMed Central

    Shapiro, Johanna; Nguyen, Vincent P; Mourra, Sarah; Boker, John R; Ross, Marianne; Thai, Trung M; Leonard, Robert J

    2009-01-01

    Background The anatomy course offers important opportunities to develop professionalism at an early stage in medical education. It is an academically significant course that also engenders stress in some students. Methods Over a three-year period, 115 of 297 students completed creative projects. Thirty-four project completers and 47 non-completers consented to participate in the study. Projects were analyzed for professionalism themes using grounded theory. A subset of project completers and non-completers were interviewed to determine their views about the stress of anatomy and medical school, as well as the value of the creative projects. We also compared test performance of project completers and non-completers. Results Projects completed early in the course often expressed ambivalence about anatomy, whereas later projects showed more gratitude and sense of awe. Project completers tended to report greater stress than noncompleters, but stated that doing projects reduced stress and caused them to develop a richer appreciation for anatomy and medicine. Project completers performed significantly lower than non-completers on the first written exam (pre-project). Differences between groups on individual exams after both the first and second creative project were nonsignificant. Conclusion For some students, creative projects may offer a useful way of reflecting on various aspects of professionalism while helping them to manage stress. PMID:19887011

  3. NCI & Division Obligations

    Cancer.gov

    Displays obligations for grants, contracts, training fellowships, intramural research, and management and support, including the number of grant awards, funding amounts, and percent of the total NCI budget.

  4. NCI-MATCH

    Cancer.gov

    The NCI-Molecular Analysis for Therapy Choice (NCI-MATCH) trial is a clinical trial that will analyze patientsí tumors to determine whether they contain genetic abnormalities upon which a drug could have an effect (termed ďactionable mutationsĒ) and assign treatment based on which abnormality is present.

  5. NCI Rare Tumor Initiative

    Cancer.gov

    The mission of the Rare Tumors Initiative is to better leverage existing NCI expertise in basic and clinical science studies of rare tumors to identify and more effectively translate potential new therapies. The NCI Rare Tumor Initiative was launched in 2

  6. NCI GeoViewer Data

    Cancer.gov

    Skip to Main Content at the National Institutes of Health | www.cancer.gov Search: Submit Home Overview About GIS GIS at NCI GIS Resources GIS Special Interest Group NCI GIS Portal Overview NCI Geoviewer NCI Map Stories Animated Historical Cancer

  7. 78 FR 52204 - Proposed Collection; 60-day Comment Request: NIH NCI Central Institutional Review Board (CIRB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-22

    ... proposed data collection projects, the National Cancer Institute (NCI), National Institutes of Health (NIH... project, contact: CAPT Michael Montello, Pharm. D., MBA, Cancer Therapy Evaluation Program, Operations and... (NCI), 0925-0625, Revision, National Cancer Institute (NCI), National Institutes of Health (NIH)....

  8. NCI at ASCO

    Cancer.gov

    NCI-designated cancer centers are being extensively represented at the annual meeting of the American Society for Clinical Oncology meeting in Chicago this year with a large array of clinical trial results and findings.

  9. NCI Translational Science Meeting

    Cancer.gov

    Prioritization Process Cross-pathway specific criteria determined and weighted NCI leadership Intra-pathway Prioritization Executive Decisions Inter-pathway Prioritization Pathway-specific criteria determined and weighted What else is needed?

  10. NCI Translational Science Meeting

    Cancer.gov

    TRWG Implementation Update Lynn M. Matrisian, Ph.D. Coordinating Center for Clinical Trials National Cancer Institute ē Coordinated Management Ė Integrated NCI management Ė Budget designation Ė TR coding Ė Prioritization process ē Tailored Funding Ė

  11. NCI Cohort Consortium Membership

    Cancer.gov

    The NCI Cohort Consortium membership is international and includes investigators responsible for more than 40 high-quality cohorts who are studying large and diverse populations in more than 15 different countries.

  12. NCI Cohort Consortium Leadership

    Cancer.gov

    Skip to Main Content at the National Institutes of Health | www.cancer.gov Epidemiology and Genomics Research In NCI's Division of Cancer Control and Population Sciences Search EGRP: Main Menu EGRP Home About the Program Mission & Vision Organizational

  13. NCI Contact Center

    Cancer.gov

    The NCI offers free, scientifically accurate, and easy-to-understand information on a range of cancer topics in English and Spanish. Get live help from compassionate information specialists at 1-800-4-CANCER.

  14. Newsletter: NCI CAM News-OCCAM

    Cancer.gov

    Contact Us | Sitemap CAM at the NCI NCI CAM History Highlights of NCI CAM Activities NCI CAM Annual Report Research Funding Opportunities Grant Application Information Research Resources Funded Research Research Results Training Opportunities FAQ's

  15. CAM Research Sponsored by NCI-OCCAM

    Cancer.gov

    Contact Us | Sitemap CAM at the NCI NCI CAM History Highlights of NCI CAM Activities NCI CAM Annual Report Research Funding Opportunities Grant Application Information Research Resources Funded Research Research Results Training Opportunities FAQ's

  16. Characterization of Apparently Balanced Chromosomal Rearrangements from the Developmental Genome Anatomy Project

    PubMed Central

    Higgins, Anne W.; Alkuraya, Fowzan S.; Bosco, Amy F.; Brown, Kerry K.; Bruns, Gail A.P.; Donovan, Diana J.; Eisenman, Robert; Fan, Yanli; Farra, Chantal G.; Ferguson, Heather L.; Gusella, James F.; Harris, David J.; Herrick, Steven R.; Kelly, Chantal; Kim, Hyung-Goo; Kishikawa, Shotaro; Korf, Bruce R.; Kulkarni, Shashikant; Lally, Eric; Leach, Natalia T.; Lemyre, Emma; Lewis, Janine; Ligon, Azra H.; Lu, Weining; Maas, Richard L.; MacDonald, Marcy E.; Moore, Steven D.P.; Peters, Roxanna E.; Quade, Bradley J.; Quintero-Rivera, Fabiola; Saadi, Irfan; Shen, Yiping; Shendure, Jay; Williamson, Robin E.; Morton, Cynthia C.

    2008-01-01

    Apparently balanced chromosomal rearrangements in individuals with major congenital anomalies represent natural experiments of gene disruption and dysregulation. These individuals can be studied to identify novel genes critical in human development and to annotate further the function of known genes. Identification and characterization of these genes is the goal of the Developmental Genome Anatomy Project (DGAP). DGAP is a multidisciplinary effort that leverages the recent advances resulting from the Human Genome Project to increase our understanding of birth defects and the process of human development. Clinically significant phenotypes of individuals enrolled in DGAP are varied and, in most cases, involve multiple organ systems. Study of these individuals' chromosomal rearrangements has resulted in the mapping of 77 breakpoints from 40 chromosomal rearrangements by FISH with BACs and fosmids, array CGH, Southern-blot hybridization, MLPA, RT-PCR, and suppression PCR. Eighteen chromosomal breakpoints have been cloned and sequenced. Unsuspected genomic imbalances and cryptic rearrangements were detected, but less frequently than has been reported previously. Chromosomal rearrangements, both balanced and unbalanced, in individuals with multiple congenital anomalies continue to be a valuable resource for gene discovery and annotation. PMID:18319076

  17. nci-2007-fact-book

    Cancer.gov

    Former Directors of the NCI.......................................................... O-2 National Cancer Advisory Board................................................... O-3 Boards of Scientific Counselors and Advisors .............................. O-7 President's Cancer Panel ............................................................. O-8 Executive Committee Members .................................................... O-8 NCI Directorís Consumer Liaison Group.

  18. NCI Interactive Budget Analysis Tool

    Cancer.gov

    skip to content Home Financial Data Cancer Statistics Contribute About OBF Financial Data Budget Formulation & Justification Plan & Budget Proposal Congressional Justification Congressional Appropriations Documents Historical Spending NCI Fact Book NCI

  19. The LINDSAY Virtual Human Project: An immersive Approach to Anatomy and Physiology

    ERIC Educational Resources Information Center

    Tworek, Janet K.; Jamniczky, Heather A.; Jacob, Christian; HallgrŪmsson, Benedikt; Wright, Bruce

    2013-01-01

    The increasing number of digital anatomy teaching software packages challenges anatomy educators on how to best integrate these tools for teaching and learning. Realistically, there exists a complex interplay of design, implementation, politics, and learning needs in the development and integration of software for education, each of which may beÖ

  20. Humanities in Gross Anatomy Project: A Novel Humanistic Learning Tool at Des Moines University

    ERIC Educational Resources Information Center

    Canby, Craig A.; Bush, Traci A.

    2010-01-01

    Gross anatomy affords physical therapy students an opportunity to discover human morphology by intimately studying the dead. Moreover, it also exposes future physical therapists to the humanistic aspects of the profession. In 2007, anatomy faculty decided to socialize students to the humanities with a new course requirement: Humanities in GrossÖ

  1. The LINDSAY Virtual Human Project: An immersive Approach to Anatomy and Physiology

    ERIC Educational Resources Information Center

    Tworek, Janet K.; Jamniczky, Heather A.; Jacob, Christian; Hallgrímsson, Benedikt; Wright, Bruce

    2013-01-01

    The increasing number of digital anatomy teaching software packages challenges anatomy educators on how to best integrate these tools for teaching and learning. Realistically, there exists a complex interplay of design, implementation, politics, and learning needs in the development and integration of software for education, each of which may be…

  2. NCI Relapse Workshop November 2009

    Cancer.gov

    For question about this site contact Brenda Boersma (NCI) boersmab@mail.nih.gov For questions about the NCI relapse after transplant program contact Alan Wayne (NCI) waynea@mail.nih.gov To learn more about the Center for Cancer Research please visit http:

  3. NCI-Frederick - Yellow Task Request System

    Cancer.gov

    This web-based system enables investigators to request services and obtain cost and time estimates for each project. NCI approval is an integral function of this process, which ensures that adequate funding and other resources are available to perform the work.

  4. NCI Grant Application Development, Submission, and Award

    Cancer.gov

    The NCI grants process is similar to the National Institutes of Health (NIH) grants process; it is rigorous and complex to ensure applications proposing promising scientific research projects are evaluated and awarded, and that the results are disseminated to the American public.

  5. 2011 NCI Cohort Consortium Annual Meeting

    Cancer.gov

    The annual NCI Cohort Consortium meeting, sponsored by EGRP and the Division of Cancer Epidemiology and Genetcis (DCEG), was held October 26, 2011 in Boston, MA. Project meetings were held on October 25, 2011. If you have questions about the meeting, contact Nonye Harvey at the National Cancer Institute.

  6. NCI-Frederick Laboratory Animal Science Program

    Cancer.gov

    The services of LASP laboratories and facilities may be accessed using the "Yellow Task Request System" and Accessions System. These web-based systems enable investigators to request services and obtain cost and time estimates for each project. NCI approval is an integral function of these processes, which ensures that adequate funding and other resources are available to perform the work.

  7. NCI Cohort Consortium

    Cancer.gov

    The NCI Cohort Consortium is an extramural-intramural partnership formed by the National Cancer Institute to address the need for large-scale collaborations to pool the large quantity of data and biospecimens necessary to conduct a wide range of cancer studies.

  8. Hojas informativas del NCI

    Cancer.gov

    La colección de hojas informativas del NCI trata de una variedad de temas relacionados con el cáncer. Las hojas informativas se revisan y ponen al día de acuerdo a las investigaciones más recientes sobre el cáncer.

  9. NCI Visuals Online

    Cancer.gov

    NCI Visuals Online contains images from the collections of the National Cancer Institute's Office of Communications and Public Liaison, including general biomedical and science-related images, cancer-specific scientific and patient care-related images, and portraits of directors and staff of the National Cancer Institute.

  10. NCI Rare Tumor Initiative

    Cancer.gov

    Contact Information   For more information on the Rare Tumors Initiative or to become a member please contact:   Abby Sandler, Ph.D. Special Assistant to the Director, Rare Tumors Initiative, OD, CCR, NCI 301-496-9983 sandlera@mail.nih.gov Karlyne Reilly,

  11. NCI Best Practices

    Cancer.gov

    This informational publication issued by the NCI OBBR is designed to increase awareness and understanding among advocates and the interested public of the importance and role of biospecimens in cancer research. It outlines the need for and purpose of best practices for biospecimen resources.

  12. NCI OA Contract Awards

    Cancer.gov

    This is a searchable database of contracts awarded by the NCI Office of Acquisitions since Fiscal Year 1995. The database is searchable by the Contract Number, the Contractor's Name, or the Title of the Contract. When searching by Contractor or Title, it is NOT neccesary to enter the complete name or title.

  13. CISNET: NCI Bulletin Articles

    Cancer.gov

    The NCI Cancer Bulletin is an award-winning biweekly online newsletter designed to provide useful, timely information about cancer research to the cancer community. The material is entirely in the public domain and can be repurposed or reproduced without permission. Citation of the source is appreciated.

  14. Larynx Anatomy

    MedlinePLUS

    ... My Pictures Browse Search Quick Search Image Details Larynx Anatomy View/Download: Small: 648x576 View Download Add to My Pictures Title: Larynx Anatomy Description: Anatomy of the larynx; drawing shows ...

  15. Vulva Anatomy

    MedlinePLUS

    ... Pictures Browse Search Quick Search Image Details Vulva Anatomy View/Download: Small: 720x634 View Download Add to My Pictures Title: Vulva Anatomy Description: Anatomy of the vulva; drawing shows the ...

  16. Pharynx Anatomy

    MedlinePLUS

    ... Pictures Browse Search Quick Search Image Details Pharynx Anatomy View/Download: Small: 720x576 View Download Add to My Pictures Title: Pharynx Anatomy Description: Anatomy of the pharynx; drawing shows the ...

  17. NCI: SBIR & STTR - Investor Forum

    Cancer.gov

    The National Cancer Institute (NCI) Small Business Innovation Research (SBIR) program hosted the 2012 NCI SBIR Investor Forum on April 18, 2012 in Santa Clara, CA. This yearís meeting brought together nearly 200 SBIR-funded companies, investors, venture capitalists, strategic partners, and business leaders from the biotech and pharmaceutical industries, and featured presentations from 18 top NCI SBIR-funded companies with innovative cancer-related technologies on the brink of commercialization.

  18. Data Sets from Major NCI Initiaves

    Cancer.gov

    The NCI Data Catalog includes links to data collections produced by major NCI initiatives and other widely used data sets, including animal models, human tumor cell lines, epidemiology data sets, genomics data sets from TCGA, TARGET, COSMIC, GSK, NCI60.

  19. Project TAPS. Teaching Anatomy with Programmed Schematics. Progress Report Number 1.

    ERIC Educational Resources Information Center

    Desch, S. H.; Stolurow, L. M.

    Experimental Programed Instruction of the anatomy of the maxillary division of the trigeminal nerve is being conducted by the Harvard Computer-Aided Instruction Laboratory in cooperation with Tufts University Dental School. Two nearly identical programs are presented, one (PF) using representational diagrams and the other (PD) a schematic diagram…

  20. Pros and Cons of a Group Webpage Design Project in a Freshman Anatomy and Physiology Course

    ERIC Educational Resources Information Center

    Crisp, Kevin M.; Jensen, Murray; Moore, Randy

    2007-01-01

    To generate motivation and promote the development of written communication skills, students in a freshman-level anatomy and physiology course for nonmajors created group webpages describing historically important diseases. After the groups had been formed, each individual was assigned specific components of the disease (e.g., causes orÖ

  1. nci-2008-fact-book

    Cancer.gov

    Former Directors of the NCI.......................................................... O-2 National Cancer Advisory Board.................................................O-3A National Cancer Advisory Board, Continued................................O-3B Boards of Scientific Counselors and Advisors .............................. O-7 President's Cancer Panel ............................................................. O-8 Executive Committee Members .................................................... O-8 NCI Directorís Consumer Liaison Group.

  2. NCI Mouse Repository- Protocol Information

    Cancer.gov

    ICR-Tg(GFAP-CDK4)2Gtm/Nci PCR Protocol Strain: ICR-Tg(GFAP-CDK4)2Gtm/Nci Strain Code: 01XK1 Protocol Number: 1 Introductory Comment: The primer set was taken from the following published paper: Oncogene 21:1325-1334. The primer set amplifies the GFAP

  3. Digital Standards for NCI Websites

    Cancer.gov

    The Digital Standards for NCI Websites and Social Media provide developers and content managers guidance on the visual and content standards, as well as policies and procedures, in effect for National Cancer Institute (NCI) digital media ‚Äď including traditional and mobile websites, as well as social and new media channels.

  4. NCI Mouse Repository- Protocol Information

    Cancer.gov

    FVB/N-Tg(Tyr-HRAS)60Lc/Nci PCR Protocol Strain: FVB/N-Tg(Tyr-HRAS)60Lc/Nci Strain Code: 01XB5 Protocol Number: 1 Introductory Comment: Primers: †H001 : † 5'-cAG ATc AAA cGG GTG AAG G -3' †H002 : † 5'-GTc TTG Gcc GAG GTc TcG -3' Product Sizes: ††Primer

  5. NCI Mouse Repository- Protocol Information

    Cancer.gov

    FVB;129-Brca1tm1Brn/Nci PCR Protocol Strain: FVB;129-Brca1tm1Brn/Nci Strain Code: 01XB8 Protocol Number: 1 Introductory Comment: The strain Brca1 has loxP sites flanking Exon region. The primer set B008/B009 tests for the presence of the upstream lox

  6. NCI Mouse Repository- Protocol Information

    Cancer.gov

    SWR.129P2(Cg)-Brca2tm1Kamc/Nci PCR Protocol Strain: SWR.129P2(Cg)-Brca2tm1Kamc/Nci Strain Code: 01XG9 Protocol Number: 2 Introductory Comment: The primer set for genotyping Brca2 comes from the paper Cancer Research 62:990-994,2002. The wildtype primer

  7. NCI Mouse Repository- Protocol Information

    Cancer.gov

    FVB;129-TgTn(sb-T2/Onc)68Dla/Nci PCR Protocol Strain: FVB;129-TgTn(sb-T2/Onc)68Dla/Nci Strain Code: 01XN9 Protocol Number: 1 Introductory Comment: This strain carries the Sleeping Beauty transposon (sb) concatemers. This strain and FVB-TgTn(sb-T2/Onc)76Dla

  8. NCI Mouse Repository- Protocol Information

    Cancer.gov

    FVB.129-Cdkn2atm2.1Rdp/Nci PCR Protocol Strain: FVB.129-Cdkn2atm2.1Rdp/Nci Strain Code: 01XE4 Protocol Number: 1 Introductory Comment: Primers: †C015 : † 5'-ggc aaa tag cgc cac cta t -3' †C016 : † 5'-gac tcc atg ctg ctc cag at -3' †C017 : † 5'-gcc

  9. NCI Mouse Repository- Protocol Information

    Cancer.gov

    B6;CBA-Tg(BCR/ABL)623Hkp/Nci PCR Protocol Strain: B6;CBA-Tg(BCR/ABL)623Hkp/Nci Strain Code: 01XE8 Protocol Number: 1 Introductory Comment: This strain carries a human BCR / ABL fusion protein, which serves as a model for the Philadelphia chromosome.

  10. NCI Mouse Repository- Protocol Information

    Cancer.gov

    FVB/N-Tg(MT-HGFSF)19Lmb/Nci PCR Protocol Strain: FVB/N-Tg(MT-HGFSF)19Lmb/Nci Strain Code: 01XFA Protocol Number: 1 Introductory Comment: This strain contains a transgene that overexpresses mouse Scatter Factor / hepatocyte growth factor, under the control

  11. NCI Mouse Repository- Protocol Information

    Cancer.gov

    FVB-TgTn(sb-T2/Onc)76Dla/Nci PCR Protocol Strain: FVB-TgTn(sb-T2/Onc)76Dla/Nci Strain Code: 01XN8 Protocol Number: 1 Introductory Comment: This strain carries the Sleeping Beauty transposon (sb) concatemers. This strain and FVB-TgTn(sb-T2/Onc)68Dla (01XN9)

  12. NCI Mouse Repository- Protocol Information

    Cancer.gov

    STOCK Tg(NES-tv-a)J12Ech/Nci PCR Protocol Strain: STOCK Tg(NES-tv-a)J12Ech/Nci Strain Code: 01XH4 Protocol Number: 1 Introductory Comment: This primer set is used for both the Tg(NES-tv-a)J12Ech and Tg(GFPA-tv-a)10Ech mouse strains. The reaction requires

  13. NCI Mouse Repository- Protocol Information

    Cancer.gov

    STOCK Brca2tm1Brn/Nci PCR Protocol Strain: STOCK Brca2tm1Brn/Nci Strain Code: 01XB9 Protocol Number: 1 Introductory Comment: The strain Brca2 has loxP sites flanking Exon11. The primer set B012/B013 tests for the presence of the upstream lox site while

  14. NCCCP Guide to NCI Resources

    Cancer.gov

    NCI Community Cancer Centers Program Guide to NCI Resources The National Cancer Institute is committed to making progress against different cancer types through varied approaches. To this end, it develops, funds, and disseminates a vast array of programs, materials, and resources.

  15. Anatomy and art.

    PubMed

    Laios, Konstantinos; Tsoukalas, Gregory; Karamanou, Marianna; Androutsos, George

    2013-01-01

    Leonardo da Vinci, Jean Falcon, Andreas Vesalius, Henry Gray, Henry Vandyke Carter and Frank Netter created some of the best atlases of anatomy. Their works constitute not only scientific medical projects but also masterpieces of art. PMID:24640589

  16. The LINDSAY Virtual Human Project: an immersive approach to anatomy and physiology.

    PubMed

    Tworek, Janet K; Jamniczky, Heather A; Jacob, Christian; Hallgrímsson, Benedikt; Wright, Bruce

    2013-01-01

    The increasing number of digital anatomy teaching software packages challenges anatomy educators on how to best integrate these tools for teaching and learning. Realistically, there exists a complex interplay of design, implementation, politics, and learning needs in the development and integration of software for education, each of which may be further amplified by the somewhat siloed roles of programmers, faculty, and students. LINDSAY Presenter is newly designed software that permits faculty and students to model and manipulate three-dimensional anatomy presentations and images, while including embedded quizzes, links, and text-based content. A validated tool measuring impact across pedagogy, resources, interactivity, freedom, granularity, and factors outside the immediate learning event was used in conjunction with observation, field notes, and focus groups to critically examine the impact of attitudes and perceptions of all stakeholders in the early implementation of LINDSAY Presenter before and after a three-week trial period with the software. Results demonstrate that external, personal media usage, along with students' awareness of the need to apply anatomy to clinical professional situations drove expectations of LINDSAY Presenter. A focus on the software over learning, which can be expected during initial orientation, surprisingly remained after three weeks of use. The time-intensive investment required to create learning content is a detractor from user-generated content and may reflect the consumption nature of other forms of digital learning. Early excitement over new technologies needs to be tempered with clear understanding of what learning is afforded, and how these constructively support future application and integration into professional practice. PMID:22791664

  17. Paraganglioma Anatomy

    MedlinePLUS

    ... Pictures Browse Search Quick Search Image Details Paraganglioma Anatomy View/Download: Small: 648x576 View Download Add to My Pictures Title: Paraganglioma Anatomy Description: Paraganglioma of the head and neck; drawing ...

  18. NCI DEA - NCI Grant Guidelines and Descriptions

    Cancer.gov

    NIH Director's New Innovator Awards The DP2 NIH Directorís New Innovator Awards provide support to highly innovative research projects by new investigators in all areas of biomedical and behavioral research.

  19. NCI Women Scientist Advisors (WSA)

    Cancer.gov

    NIH WSA Website Women in Biomedical Careers NIH Office on Research on Women's Health AACR-Women in Cancer Research NCI Office of Workforce Development For assistance with Career Development, Managers' Toolbox, Organizational Development, Work Life Issues

  20. NCI-Frederick PHL - Pathology

    Cancer.gov

    PHL pathologists function as scientific collaborators assisting in animal study design, species selection, histopathology and immunohistopathology evaluation, photomicrography, report and manuscript preparation. This is in keeping with NCI-Frederick's research mission.

  1. NCI Interactive Budget Analysis Tool

    Cancer.gov

    Supports planning for new programs, expansion or modification of existing resources, and feasibility studies to explore various approaches to the development of interdisciplinary programs that offer potential solutions to problems of special significance to the mission of the NCI.

  2. NCI: SBIR & STTR - Success Stories

    Cancer.gov

    The National Cancer Institute's (NCI) Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs are an important source of early-stage technology financing for small businesses.

  3. nci-2011-fact-book

    Cancer.gov

    Fiscal Year 2011 Annual Report ......................................................iii Director's Biography .................................................................... O-1 Former Directors of the NCI......................................................... O-2 National Cancer Advisory Board.................................................. O-4 Boards of Scientific Counselors and Advisors.............................. O-8 President's Cancer Panel ............................................................ O-9 Scientific Program Leaders.

  4. NCI: SBIR & STTR - Funding Opportunities

    Cancer.gov

    The NCI SBIR Development Center hosted a special informational webinar on the Phase IIB Bridge Award Program. Download slides and an audio recording from this webinar through our SBIR Presentations page.

  5. NCI-Frederick PHL - Services

    Cancer.gov

    PHL pathologists function as scientific collaborators assisting in animal study design, species selection, histopathology and immunohistopathology evaluation, photomicrography, report and manuscript preparation. This is in keeping with NCI-Frederick's research mission.

  6. NCI Mouse Repository- Protocol Information

    Cancer.gov

    B6;129-Dmtf1tm1Cjs/Nci PCR Protocol Strain: B6;129-Dmtf1tm1Cjs/Nci Strain Code: 01XH1 Protocol Number: 1 Introductory Comment: Primers: †D001 : † 5'-GAT GGT ccA ccA TTT AcT TcG -3' †D003 : † 5'-GcT GTA GcT GAA AGA GTG GGT Ac -3' †D002 : † 5'-AGT ATc

  7. NCI Mouse Repository- Protocol Information

    Cancer.gov

    FVB;129-Men1tm1.1Ctre/Nci PCR Protocol Strain: FVB;129-Men1tm1.1Ctre/Nci Strain Code: 01XC7 Protocol Number: 1 Introductory Comment: Primers: †M014 : † 5'-ccc AcA Tcc AGT ccc TcT TcA GcT -3' †M015 : † 5'-ccc TcT GGc TAT TcA ATG GcA GGG -3' †M016 :

  8. NCI Mouse Repository- Protocol Information

    Cancer.gov

    FVB-Tg(ARR2/Pbsn-MYC)7Key/Nci PCR Protocol Strain: FVB-Tg(ARR2/Pbsn-MYC)7Key/Nci Strain Code: 01XK8 Protocol Number: 1 Introductory Comment: In the FVB-Tg(ARR2/Pbsn-MYC)7Key strain, MO45 is specific for the ARR2Pb Promoter element, and MO47 is specific

  9. NCI Mouse Repository- Protocol Information

    Cancer.gov

    B6;129S-Nkx3-1tm3(cre)Mms/Nci PCR Protocol Strain: B6;129S-Nkx3-1tm3(cre)Mms/Nci Strain Code: 01XBP Protocol Number: 1 Introductory Comment: The primers are designed to detect the Nkx3.1 gene mutant and wild type. Primers: †BP5 : † 5'-CTC CGC TAC CCT

  10. NCI Mouse Repository- Protocol Information

    Cancer.gov

    129X1/SvJ-Tg(TH-MYCN)41Waw/Nci PCR Protocol Strain: 129X1/SvJ-Tg(TH-MYCN)41Waw/Nci Strain Code: 01XD2 Protocol Number: 1 Introductory Comment: Primers: †N008 : † 5'-TGG AAA GcT TcT TAT TGG TAG AAA cAA -3' †N009 : † 5'-AGG GAT ccT TTc cGc ccc GTT cGT

  11. NCI Mouse Repository- Protocol Information

    Cancer.gov

    FVB.129-Cdkn2atm1Nesh/Nci PCR Protocol Strain: FVB.129-Cdkn2atm1Nesh/Nci Strain Code: 01XJ2 Protocol Number: 1 Introductory Comment: Primers: †C029 : † 5'-ATG TTc AcG AAA Gcc AGA Gc -3' †C030 : † 5'-GTc GcA GGT TcT TGG TcA cT -3' Product Sizes: ††Primer

  12. NCI Mouse Repository- Protocol Information

    Cancer.gov

    STOCK Tgfb1tm1Doe Rag2tm1Fwa/Nci PCR Protocol Strain: STOCK Tgfb1tm1Doe Rag2tm1Fwa/Nci Strain Code: 01XA6 Protocol Number: 1 Introductory Comment: Primers: †T001 : † 5'-GAG AAG AAc TGc TGT GTG cG -3' †T003 : † 5'-Gcc GAG AAA GTA Tcc ATc AT -3' †T002

  13. NCI Mouse Repository- Protocol Information

    Cancer.gov

    FVB.129P2-Trp53tm1Brn/Nci PCR Protocol Strain: FVB.129P2-Trp53tm1Brn/Nci Strain Code: 01XC2 Protocol Number: 1 Introductory Comment: Primers: †T008 : † 5'-cAc AAA AAc AGG TTA AAc ccA G -3' †T009 : † 5'-AGc AcA TAG GAG GcA GAG Ac -3' Product Sizes:

  14. NCI Mouse Repository- Protocol Information

    Cancer.gov

    STOCK Col1a1tm1(CAG-EGFR)Char/Nci PCR Protocol Strain: STOCK Col1a1tm1(CAG-EGFR)Char/Nci Strain Code: 01X67 Protocol Number: 1 Introductory Comment: Primers: †67C1 : † 5'-GCA CAG CAT TGC GGA CAT GC -3' †67C3 : † 5'-GCA GAA GCG CGG CCG TCT GG -3' †67C2

  15. NCI Mouse Repository- Protocol Information

    Cancer.gov

    C57BL/6N-Tg(Igl-MYC)3Hm/Nci PCR Protocol Strain: C57BL/6N-Tg(Igl-MYC)3Hm/Nci Strain Code: 01XA7 Protocol Number: 1 Introductory Comment: Primers: †M017 : † 5'-cTG cTG GTG GTG GGc GGT GTc Tc -3' †M018 : † 5'-TGT ccA AAG GGG GTG AAA GGG TGc Tc -3' Product

  16. NCI Mouse Repository- Protocol Information

    Cancer.gov

    B6.129-Msh2tm1Rak/Nci PCR Protocol Strain: B6.129-Msh2tm1Rak/Nci Strain Code: 01XA5 Protocol Number: 1 Introductory Comment: Primers: †M004 : † 5'-ccc Tcc TGT TGA Gcc ATc TTA -3' †M005 : † 5'-Gcc AGc TcA TTc cTc cAc Tc -3' †M006 : † 5'-TTc GTc GcT

  17. Governance ó CBIIT: Welcome to the NCI Center for Biomedical Informatics and Information Technology

    Cancer.gov

    Established in mid-2011 by the NCAB, the IWG is charged with providing strategic guidance and direction on NCI informatics investments that support the Instituteís scientific goals. The IWG provides a venue for identifying high-priority biomedical informatics needs, harmonizing ongoing and proposed informatics projects across NCI programs, both intramural and extramural, and reducing redundancies wherever possible.

  18. Constructing failure in big biology: The socio-technical anatomy of Japan's Protein 3000 Project.

    PubMed

    Fukushima, Masato

    2016-02-01

    This study focuses on the 5-year Protein 3000 Project launched in 2002, the largest biological project in Japan. The project aimed to overcome Japan's alleged failure to contribute fully to the Human Genome Project, by determining 3000 protein structures, 30 percent of the global target. Despite its achievement of this goal, the project was fiercely criticized in various sectors of society and was often branded an awkward failure. This article tries to solve the mystery of why such failure discourse was prevalent. Three explanatory factors are offered: first, because some goals were excluded during project development, there was a dynamic of failed expectations; second, structural genomics, while promoting collaboration with the international community, became an 'anti-boundary object', only the absence of which bound heterogeneous domestic actors; third, there developed an urgent sense of international competition in order to obtain patents on such structural information. PMID:26983170

  19. GSRP - NCI Graduate Student Recruiting Program

    Cancer.gov

    The National Cancer Institute (NCI) seeks candidates to participate in the Graduate Student Recruiting Program, which is held yearly in Bethesda, Maryland. The purpose of this event is to recruit outstanding senior graduate students to postdoctoral positions at the NCI.

  20. 2013 NCI Cohort Consortium Annual Meeting

    Cancer.gov

    The annual NCI Cohort Consortium meeting, sponsored by EGRP and the Division of Cancer Epidemiology and Genetics (DCEG), was held on November 18-19, 2013, at the NCI Shady Grove Campus in Rockville, Maryland.

  1. Join TTC! | NCI Technology Transfer Center | TTC

    Cancer.gov

    The NCI Technology Transfer Center (TTC) offers a unique opportunity for training through the NCI TTC Fellowship program. TTC also has a unit dedicated to marketing these research opportunities and their underlying technologies to potential collaborators and licensees.

  2. NCI Mouse Repository- Protocol Information

    Cancer.gov

    C3H/He-Tg(RIP1-Tag5)5Dh/Nci PCR Protocol Strain: C3H/He-Tg(RIP1-Tag5)5Dh/Nci Strain Code: 01XD4 Protocol Number: 1 Introductory Comment: Primers: †T018 : † 5'-GGA cAA Acc AcA AcT AGA ATG cAG -3' †T020 : † 5'-cAc cGG AGA ATG GGA AGc cGA A -3' †T019

  3. Teleconference Summary: NCI Clinical Trials Systems

    Cancer.gov

    Over the course of several years, NCI has held extensive discussions with stakeholders, including the scientific and advocacy communities and national advisory boards, about ways to improve and modernize the NCI clinical trials systems (e.g., the 2005 NCI Clinical Trials Working Group Report, the 2010 NCI Operational Efficiency Working Group Report, and the 2010 Institute of Medicine Report). Each of these reports, coupled with regular input from our stakeholders, guided the current changes.

  4. NCI Alliance for Nanotechnology in Cancer - NCI Alliance Bulletin

    Cancer.gov

    The NCI Alliance for Nanotechnology in Cancer Bulletin is a resource that serves to connect Alliance participants, partners, and affiliates by highlighting the innovative work of the Alliance members in their efforts to harness the power of nanotechnology to radically change the way we diagnose, treat, and prevent cancer.

  5. Robert Wiltrout Says Goodbye to NCI in 2015 | Poster

    Cancer.gov

    After 34 years at NCI, Robert Wiltrout, Ph.D., said he is looking forward to trading his I-270 commute for another type of commute: exploring the waterways of Maryland, Alaska, and Wyoming to fulfill his love of fishing. Wiltrout officially retired as director of the NCI Center for Cancer Research (CCR) on July 2 of last year. Throughout his college academic career, Wiltrout had an interest in science, but it was not until he was working on a research project for his master’s degree that he considered a career in scientific research.

  6. Robert Wiltrout Says Goodbye to NCI in 2015 | Poster

    Cancer.gov

    After 34 years at NCI, Robert Wiltrout, Ph.D., said he is looking forward to trading his I-270 commute for another type of commute: exploring the waterways of Maryland, Alaska, and Wyoming to fulfill his love of fishing. Wiltrout officially retired as director of the NCI Center for Cancer Research (CCR) on July 2 of last year. Throughout his college academic career, Wiltrout had an interest in science, but it was not until he was working on a research project for his masterís degree that he considered a career in scientific research.

  7. NCI CAM News Fall 2009, Vol 4, Issue 1

    Cancer.gov

    In July 2008, the United States government signed a research agreement with China to foster collaboration between researchers studying integrative andTraditional Chinese Medicine (TCM) in both countries. One of thefirst and most promising of these projects is a partnership between the Kunming Institute of Botany (KIB) of China Academy of Sciences and two groups at the National Cancer Institute (NCI).

  8. NCI: SBIR & STTR - Success Story - SBIR Phase II Bridge Award

    Cancer.gov

    The National Cancer Institute (NCI) Small Business Innovation Research Program (SBIR) Phase IIB Bridge Award is designed to support the next stage of development for promising NIH-supported SBIR Phase II projects in the areas of cancer therapies, diagnostics, and cancer imaging technologies.

  9. ‚ÄúNCI-Frederick‚ÄĚ Is Retired; Replaced with ‚ÄúNCI at Frederick‚ÄĚ | Poster

    Cancer.gov

    By Andrea Frydl, Contributing Writer If you are used to using the term ‚ÄúNCI-Frederick‚ÄĚ to identify your work location, please note that this name has been officially retired. This change was made to ensure consistency with the naming conventions used by other NCI locations, such as NCI at Shady Grove. Please be aware of the distinction between the terms ‚ÄúNCI at Frederick‚ÄĚ and ‚Äúthe NCI Campus at Frederick,‚ÄĚ as follows:

  10. NCI Women Scientist Advisors (WSA)

    Cancer.gov

    The NCI prize honors the commitment of women in cancer research and is given in tribute to Dr. Franklin, who played a critical role in the discovery of the DNA double helix. Past Award Winners Maxine Singer, Carnegie Institute, no title, January 2002 Marg

  11. NCI Relapse Workshop November 2009

    Cancer.gov

    Committee members Name Institue email Kröger, Nicolaus (Co-chair) University Hospital Hamburg-Eppendorf nkroeger@uke.uni-hamburg.de Wayne, Alan (Co-chair) NCI waynea@mail.nih.gov Bacher, Ulrike University of Hamburg u.bacher@uke.de Bader, Peter University

  12. NCI Relapse Workshop November 2009

    Cancer.gov

    This page will serve as a home page of the NCI International Workshop on The Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation held on November 2-3, 2009 at the Natcher Auditorium, Bethesda, MD, USA Mee

  13. NCI Relapse Workshop November 2009

    Cancer.gov

    Name Institute email Sub-committee Bishop, Michael NCI michael.bishop@nih.hhs.gov Co-Chair Giralt, Sergio MD Anderson sgiralt@mail.mdanderson.org Co-Chair Alyea, Edwin Dana-Farber edwin_alyea@dfci.harvard.edu Strategie/therapies to prevent relapse, Co-Cha

  14. NCI Relapse Workshop November 2009

    Cancer.gov

    Committee members Name Institue email Pavletic, Steve (Co-Chair) NCI pavletis@mail.nih.gov Weisdorf, Daniel (Co-Chair) University of Minnesota weisd001@umn.edu De Lima, Marcos MD Anderson Cancer Center mdelima@mdanderson.org Foran, James University of Ala

  15. NCI Women Scientist Advisors (WSA)

    Cancer.gov

    The NIH Women Scientist Advisors (WSA) was established 1992 for IRP women scientists to have an open forum to discuss and exchange ideas. Each WSA is elected by the women scientists of her IC or appointed and serves a two-year term. The NCI WSA's are resp

  16. nci-2010-fact-book

    Cancer.gov

    Executive Summary Organization Cancer Statistics Budget Data Extramural Programs Fiscal Year 2010 Annual Report ......................................................iii Director's Biography .................................................................... O-1 Former Directors of the NCI......................................................... O-2 National Cancer Advisory Board.................................................. O-4 Boards of Scientific Counselors and Advisors.............................. O-8 President's Cancer Panel ............................................................ O-9 Scientific Program Leaders.

  17. Student-Authored Hypermedia in Veterinary Anatomy: Teaching and Learning Outcomes of Group Project Work.

    ERIC Educational Resources Information Center

    Garvin, Anthony; Carrington, Stephen

    1997-01-01

    Describes the Directed-Self Education program at the University of Bristol (England) for undergraduate small-group project work in veterinary science that was designed to support students in developing personal study and information technology skills. It also produced student-authored hypermedia tools which could be repurposed by staff as teachingÖ

  18. Heart Anatomy

    MedlinePLUS

    ... poster (PDF) The Human Heart Anatomy Blood The Conduction System The Coronary Arteries The Heart Valves The ... See also on this site: The Heartbeat The Conduction System (illustration) Electrical impulses from your heart muscle ( ...

  19. 75 FR 49938 - Proposed Collection; Comment Request; NIH NCI Central Institutional Review Board (CIRB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-16

    ... Review (FR) 1450 1 10/60 (.17 hour)......... 247 Acceptance Form (Attachment 2L). Participants Study... collection projects, the National Cancer Institute (NCI), the National Institutes of Health (NIH)...

  20. NCI DTP - Discovery Services - NCI-60 Screening Services

    Cancer.gov

    The Developmental Therapeutics Program (DTP) operates a progressive, tiered in vitro and in vivo anti-cancer compound screening program for single pure compounds with the goal of identifying and evaluating novel chemical leads and biological mechanisms of action. The program does not support screening of chemical libraries. The DTP screens include the NCI 60 cell line screen and, as appropriate, the hollow fiber assay and relevant human tumor xenograft and rodent tumor models.

  1. NCI Drug Development Collaborative

    Cancer.gov

    Things to consider prior to submitting a proposal to the DDC 1) Is the target novel? 2) Can you verify the target is not being developed by pharma? 3) Can you invest time, resources and personnel to this project for several years? 4) Is the target critica

  2. Independence and merger of thalamocortical channels within macaque monkey primary visual cortex: anatomy of interlaminar projections.

    PubMed

    Yoshioka, T; Levitt, J B; Lund, J S

    1994-01-01

    An important issue in understanding the function of primary visual cortex in the macaque monkey is how the several efferent neuron groups projecting to extrastriate cortex acquire their different response properties. To assist our understanding of this issue, we have compared the anatomical distribution of V1 intrinsic relays that carry information derived from magno- (M) and parvocellular (P) divisions of the dorsal lateral geniculate nucleus between thalamic recipient neurons and interareal efferent neuron groups within area V1. We used small, iontophoretic injections of biocytin placed in individual cortical laminae of area V1 to trace orthograde and retrograde inter- and intralaminar projections. In either the same or adjacent sections, the tissue was reacted for cytochrome oxidase (CO), which provides important landmarks for different efferent neuron populations located in CO rich blobs and CO poor interblobs in laminae 2/3, as well as defining clear boundaries for the populations of efferent neurons in laminae 4A and 4B. This study shows that the interblobs, but not the blobs, receive direct input from thalamic recipient 4C neurons; the interblobs receive relays from mid 4C neurons (believed to receive convergent M and P inputs), while blobs receive indirect inputs from either M or P (or both) pathways through layers 4B (which receives M relays from layer 4C alpha) and 4A (which receives P relays directly from the thalamus as well as from layer 4C beta). The property of orientation selectivity, most prominent in the interblob regions and in layer 4B, may have a common origin from oriented lateral projections made by mid 4C spiny stellate neurons. While layer 4B efferents may emphasize M characteristics and layer 4A efferents emphasize P characteristics, the dendrites of their constituent pyramidal neurons may provide anatomical access to the other channel since both blob and interblob regions in layers 2/3 have anatomical access to M and P driven relays, despite functional differences in the way these properties may be expressed in the two compartments. PMID:8038123

  3. Analysis of superiorly projecting anterior communicating artery aneurysms: anatomy, techniques, and outcome. A proposed classification system.

    PubMed

    Nossek, Erez; Setton, Avi; Karimi, Reza; Dehdashti, Amir R; Langer, David J; Chalif, David J

    2016-04-01

    Superiorly projecting (SP) anterior communicating artery (AComA) aneurysms are typically described as a homogenous group. Clinically and microsurgically, these aneurysms vary in multiple important characteristics. We propose a microsurgical classification system for these complex aneurysms and review its implications regarding presentation, microsurgical techniques, and outcome. This retrospective analysis reviews patients undergoing clipping of SP AComA aneurysms (2005-2013). The classification system is based on the virtual plane created by the A2 segments and its relationship to the aneurysm. Aneurysm type was assessed by intraoperative images and videos. Type 1 is defined by bisection of the dome by the virtual plane. Type 2 is defined by dome projection posterior to this plane. Sagittal rotation of the plane defines type 3. We analyzed clinical presentation, morphology, angiographic characteristics, operative technique, and outcome relative to the classification types. There were 44 SP AComA aneurysms. 3D angiographic images predicted classification type in 83¬†%. Type 1 presented more often with SAH (95.5¬†%, p‚ÄČ=‚ÄČ0.0046). There was no statistically significant difference between the types regarding patient demographics or aneurysm characteristics. In type 2, fenestrated clips were used frequently (87.5¬†% p=‚ÄČ0.0016), and there was higher rate of intraoperative rupture (37.5¬†%). Although there was no statistically significant difference between the types in respect to HH grade upon presentation, patients with type 2 aneurysms experienced higher rates of poor GOS (50¬†%). The proposed classification system for SP AComA aneurysms has implications regarding surgical planning, micro-dissection, clipping, and outcome. Type 2 aneurysms carry significant surgical risk. PMID:26631225

  4. NCI Mouse Repository - Ordering Information

    Cancer.gov

    You may select to have mice recovered for you at NCI-Frederick. After their genotype and health status has been verified, live animals will be delivered to you. You will be notified when mice become available for shipping. Please expect to receive at least one mutant carrier within 16-20 weeks. There is no charge for the cryorecovery procedure. Please note that cryorecoveries may be performed in a facility that has a history of exposure to murine norovirus.

  5. NCI Community Cancer Centers Program - Related Programs - NCI Best Practices for Biospecimen Resources

    Cancer.gov

    The NCI Best Practices for Biospecimen Resources identifies best practices for biospecimen collection, processing, storage, retrieval, and dissemination and addresses concepts of good laboratory practice to ensure a level of consistency and standardization across NCI-supported biospecimen resources.

  6. NCI-Molecular Analysis for Therapy Choice (NCI-MATCH) Trial

    Cancer.gov

    Information about the NCI-Molecular Analysis for Therapy Choice (NCI-MATCH) Program, in which researchers will examine tumor tissue from patients with advanced solid tumors and lymphomas that have stopped responding to treatment

  7. International Activities of NCI Designated Cancer Centers

    Cancer.gov

    This report is not a comprehensive summary of the international efforts of NCI-Designated Cancer Centers and not all of the efforts outlined in this report are NCI or NIH-funded. Rather, this report summarizes information that was provided by Cancer Centers who responded to requests from the NCI Center for Global Health for information on international activities. This is an ongoing data- collection effort, the data collection status for individual cancer centers can be found in Appendix A.

  8. Trans-NCI Pharmacogenomics and Pharmacoepidemiology Working Group (PPWG)

    Cancer.gov

    NCI established the Trans-NCI Pharmacogenomics and Pharmacoepidemiology Working Group to support development of a comprehensive and interdisciplinary pharmacoepidemiology and pharmacogenomics cancer research program.

  9. The Anatomy of Learning Anatomy

    ERIC Educational Resources Information Center

    Wilhelmsson, Niklas; Dahlgren, Lars Owe; Hult, Hakan; Scheja, Max; Lonka, Kirsti; Josephson, Anna

    2010-01-01

    The experience of clinical teachers as well as research results about senior medical students' understanding of basic science concepts has much been debated. To gain a better understanding about how this knowledge-transformation is managed by medical students, this work aims at investigating their ways of setting about learning anatomy.…

  10. The Anatomy of Learning Anatomy

    ERIC Educational Resources Information Center

    Wilhelmsson, Niklas; Dahlgren, Lars Owe; Hult, Hakan; Scheja, Max; Lonka, Kirsti; Josephson, Anna

    2010-01-01

    The experience of clinical teachers as well as research results about senior medical students' understanding of basic science concepts has much been debated. To gain a better understanding about how this knowledge-transformation is managed by medical students, this work aims at investigating their ways of setting about learning anatomy

  11. NCI Relapse/Transplant Meeting 2012

    Cancer.gov

    Co-Chairs: Hardy, Nancy NCI hardyn@mail.nih.gov Battiwalla, Minoo NHLBI battiwam@mail.nih.gov Committee Members: Name Institute Session Miller, Jeffrey S. U of Minnesota Biology of Relapse Gress, Ron NCI Biology of Relapse Wu, Catherine Dana-Farber Cancer

  12. About the NCI Council of Research Advocates

    Cancer.gov

    The NCI Council of Research Advocates (NCRA), previously known as the Directorís Consumer Liaison Group (DCLG), is the only federal advisory committee comprised of advocate leaders at NCI. NCRA members are chosen for their expert knowledge of issues of importance to the cancer research community.

  13. NCI Mouse Repository - Ordering Cryoarchived Strains

    Cancer.gov

    All NCI Mouse Repository strains are cryopreserved and archived as frozen embryos. Quality control testing is performed at the NCI Mouse Repository to ensure viability and genetic integrity of the frozen material. One aliquot of each batch of embryos is thawed and live-born mice of the proper genotype are produced.

  14. NCI Center of Excellence in Immunology

    Cancer.gov

    Members Name and E-mail Phone Affiliation Lee Helman, MD Chair 301.496.4345 Acting Director, CCR Jonathan Ashwell, MD 301.496.4931 Laboratory of Immune Cell Biology, CCR, NCI Jay Berzofsky, MD, PhD 301.496.6874 Vaccine Branch, CCR, NCI Kevin Conlon, MD 30

  15. 2009 NCI SBIR Investor Forum Program Book

    Cancer.gov

    LETTER FROM NCI SBIR Welcome to the inaugural National Cancer Institute (NCI) Small Business Innovation Research (SBIR) Investor Forum. Thank you for joining us. I hope that today will be a valuable opportunity for you to learn more about the most

  16. Discovery | NCI Experimental Therapeutics (NExT)

    Cancer.gov

    The Advanced Technology Program (ATP) laboratories at NCI-Frederick are operated by SAIC Frederick, Inc. and were established to provide NCI and other NIH laboratories and initiatives with access to leading-edge technologies and specialized expertise through a tightly integrated, highly effective approach to the study of complex biological problems.

  17. nci-2009-fact-book

    Cancer.gov

    Total Extramural Funds 3,756.3 3,720.7 3,733.2 3,732.0 3,800.9 1.2% Mechanism 2005 2006 2007 2008 2009 05-09% chg. Intramural Research $711.0 $687.3 $706.2 $718.4 $781.4 9.9% RMS 173.7 184.1 188.7 231.0 384.6 121.4% Control Inhouse 154.0 155.0 164.5 146.3 0.0 -100.0% Total Inhouse Funds 1,038.7 1,026.5 1,059.4 1,095.7 1,166.0 12.3% Total NCI 4,795.0 4,747.2 4792.6 4,827.7 4,966.9 3.6% Inhouse National Cancer Institute Extramural vs.

  18. Normal Pancreas Anatomy

    MedlinePLUS

    ... My Pictures Browse Search Quick Search Image Details Pancreas Anatomy View/Download: Small: 761x736 View Download Add to My Pictures Title: Pancreas Anatomy Description: Anatomy of the pancreas; drawing shows ...

  19. Thymus Gland Anatomy

    MedlinePLUS

    ... My Pictures Browse Search Quick Search Image Details Thymus Gland, Adult, Anatomy View/Download: Small: 720x576 View Download Add to My Pictures Title: Thymus Gland, Adult, Anatomy Description: Anatomy of the thymus gland; ...

  20. NCI Holds on to Defelice Cup | Poster

    Cancer.gov

    NCI kept the Defelice Cup trophy this year after beating Leidos Biomedical Research, 15 to 9, at the 10th annual Ronald H. Defelice Golf Tournament held on Columbus Day. Sixteen players on each team battled it out at the yearly contractor vs. government tournament held at Rattlewood Golf Course in Mount Airy, Md. NCI leads the series 6Ė4. ďThe score was the highest NCI margin of victory in the 10-year series,Ē said Denny Dougherty, retired senior subcontracts advisor at what was formerly SAIC-Frederick. ďThe intensity of the annual competition has increased each year and has become...

  1. NCI Holds on to Defelice Cup | Poster

    Cancer.gov

    NCI kept the Defelice Cup trophy this year after beating Leidos Biomedical Research, 15 to 9, at the 10th annual Ronald H. Defelice Golf Tournament held on Columbus Day. Sixteen players on each team battled it out at the yearly contractor vs. government tournament held at Rattlewood Golf Course in Mount Airy, Md. NCI leads the series 6‚Äď4. ‚ÄúThe score was the highest NCI margin of victory in the 10-year series,‚ÄĚ said Denny Dougherty, retired senior subcontracts advisor at what was formerly SAIC-Frederick. ‚ÄúThe intensity of the annual competition has increased each year and has become...

  2. Milestones in the History of Cancer Control in Congress and at NCI - National Cancer Institute - Cancer Control and Population Sciences

    Cancer.gov

    NCI forms the Division of Cancer Prevention and Control to accelerate the science of cancer control, giving a new definition to the term and a framework that describes a linear series of phases from hypothesis generation to demonstration projects.

  3. SOP: Thawing, Propagation and Cryopreservation of NCI-PBCF-CCL256 (NCI-H2126)

    Cancer.gov

    Table of Contents 1. BACKGROUND INFORMATION ON NCI-PBCF-CCL256 (NCI-H2126) CELL LINE .........................3 2. GENERAL INFORMATION FOR THE THAWING, PROPAGATING AND CRYOPRESERVING OF NCI-PBCF-CCL256 (NCI-H2126) .................................................................................................................3 3. REAGENTS ...........................................................................................................................................5 A. PREPARATION OF COMPLETE GROWTH MEDIUM......................................................................................6 4. THAWING AND PROPAGATION OF CELLS ......................................................................................6 A. THAWING CELLS ...................................................................................................................................6 B. PROPAGATING CELLS ...........................................................................................................................7 C. SUBCULTURING CELLS ..........................................................................................................................8 5. HARVESTING OF CELLS FOR CRYOPRESERVATION ................................................................. 10 6. CRYOPRESERVATION OF CELLS .................................................................................................. 11 A. CRYOPRESERVATION USING A RATE-CONTROLLED PROGRAMMABLE FREEZER ...................................... 11 i.

  4. NCI Intramural Faculties and Working Groups

    Cancer.gov

    1) Goals The NCI intramural faculties, working groups, and interest groups are dynamic teams that provide a forum for scientists working in different areas of research to engage one another to promote interaction and communication. The goals are to: Promo

  5. 2009 NCI Cohort Consortium Annual Meeting Agenda

    Cancer.gov

    Skip to Main Content at the National Institutes of Health | www.cancer.gov Epidemiology and Genomics Research In NCI's Division of Cancer Control and Population Sciences Search EGRP: Main Menu EGRP Home About the Program Mission & Vision Organizational

  6. NCI Relapse/Transplant Meeting 2012

    Cancer.gov

    Aims of the NCI-Sponsored Second International Workshop on the Biology, Prevention, and Treatment of Relapse After Hematopoietic Stem Cell Transplantation The Primary Aim of the Workshop is to facilitate the development of multicenter clinical trials rela

  7. NCI Center of Excellence in Immunology

    Cancer.gov

    The Center of Excellence in Immunology (CEI) is one of 5 Centers of Excellence within the NCI Intramural Research Program (IRP). These Centers are multi-disciplinary venues that generate connections among diverse intellectual, financial, and physical reso

  8. NIH and NCI Grants-Related Policies

    Cancer.gov

    This section contains links compiled by the Epidemiology and Genomics Research Program (EGRP) to help investigators learn more about NIH and NCI policies related to grant applications and has FAQs related to grants policies.

  9. NCI Center of Excellence in Chromosome Biology

    Cancer.gov

    Participation CECB participation is open to all NCI intramural investigators who are interested in chromosome biology. Membership Full membership, which includes a research listing on the CECB website, is open to all CCR Principal Investigators and Senior

  10. Dinutuximab (Unituxin‚ĄĘ) | NCI Technology Transfer Center | TTC

    Cancer.gov

    In 2010, NCI entered into a Cooperative Research and Development Agreement (CRADA) with United Therapeutics Corp., under which the company assumed responsibility for manufacturing dinutuximab and moving it through the steps required for regulatory approval.

  11. NCI: Research Resources > Resources by Category

    Cancer.gov

    Skip Navigation Home Resources by Category Resources by DOC Related Links Advanced Search Integrative Cancer Biology Program (ICBP) Website NCI's extramural Integrative Cancer Biology Program (ICBP)†focuses on the analysis of cancer as a complex biological

  12. Discovery | NCI Experimental Therapeutics (NExT)

    Cancer.gov

    Skip to Content Search this site DISCOVERY NCINExTInfo@mail.nih.gov Overview Chemical Biology Consortium NExT Diversity Library Discovery Activities in DTP Discovery Activities in CCR Other NCI Programs Last Updated: 10/28/10 North

  13. NCI announces plans to reinvigorate clinical trials

    Cancer.gov

    The National Cancer Institute (NCI) has announced major changes to be made in the long-established Clinical Trials Cooperative Group Program that conducts many of the nationwide trials of new cancer therapies.

  14. NCI Relapse/Transplant Meeting 2012

    Cancer.gov

    Name Institute Gooley, Ted Fred Hutchinson Cancer Research Center Devlin, Sean Memorial Sloan-Kettering Cancer Center  Logan, Brett Medical College of Wisconsin Neuberg, Donna Harvard University Steinberg, Seth NCI Zhang, Mei-Jie Medical College of Wiscon

  15. Extramural NCI Data Access Committee: Contact Us

    Cancer.gov

    Skip to Main Content at the National Institutes of Health | www.cancer.gov Epidemiology and Genomics Research In NCI's Division of Cancer Control and Population Sciences Search EGRP: Main Menu EGRP Home About the Program Mission & Vision Organizational

  16. NCI Community Cancer Centers Program - NCCCP Homepage

    Cancer.gov

    NCI Community Cancer Centers Program - NCCCP Homepage Skip to content Related Programs Overview Cancer Centers Program Community Clinical Oncology Program (CCOPs) Minority-Based Community Clinical Oncology Program (MB-CCOPs) Cancer Trials

  17. NCI Center of Excellence in Immunology

    Cancer.gov

    Membership is open to all NCI intramural principal investigators, scientists, clinicians, and science administrators as well as scientists from other NIH institutes. Please contact Dr. Diana Linnekin if you are interested in joining. ‚Äď A ‚Äď Stephen K. Ande

  18. NCI Central Review Board Receives Accreditation

    Cancer.gov

    The Association for the Accreditation of Human Research Protection Programs has awarded the NCI Central Institutional Review Board full accreditation. AAHRPP awards accreditation to organizations demonstrating the highest ethical standards in clinical res

  19. NCI: SBIR & STTR - Investor Forum - Presenting Companies

    Cancer.gov

    The 28 SBIR-funded companies selected to present at the 2014 NCI SBIR Investor Forum represent promising innovators that are developing the next generation of cancer therapeutics, diagnostics, and devices primed for commercialization.

  20. 2008 NCI Cohort Consortium Annual Meeting Agenda

    Cancer.gov

    Skip to Main Content at the National Institutes of Health | www.cancer.gov Epidemiology and Genomics Research In NCI's Division of Cancer Control and Population Sciences Search EGRP: Main Menu EGRP Home About the Program Mission & Vision Organizational

  1. Discovery | NCI Experimental Therapeutics (NExT)

    Cancer.gov

    Skip to Content Search this site DISCOVERY NCINExTInfo@mail.nih.gov Overview Chemical Biology Consortium NExT Diversity Library Discovery Activities in DTP Discovery Activities in CCR Other NCI Programs Last Updated: 10/28/10 Georgetown

  2. NCI Imaging Sciences Working Group (ISWG)

    Cancer.gov

    Dr. Richard Klausner introduced the "Working Group concept," noting that the role of these "think tanks" is to identify an intellectually robust vision for new investment in particular areas of cancer (identified in the NCI Bypass Budget for fiscal years 1997-1998). It is expected that the Working Groups will make recommendations for actions that the NCI can take to advance research opportunities in these areas.

  3. International Fellows of NCI at Frederick | Poster

    Cancer.gov

    Each year, the Employee Diversity Team (EDT) acknowledges members of the NCI at Frederick Community for their achievements and contributions towards the mission of facility.¬† Historically, the team has profiled the ‚ÄúWomen of NCI at Frederick,‚ÄĚ but this year, the team decided to instead shed light on the diverse and successful individuals who make up the international fellows community.

  4. NCI: SBIR & STTR - Investor Forum - Contact Information

    Cancer.gov

    The NCI SBIR Investor Forum was an exclusive opportunity for 14 NCI funded companies in the diagnostic, therapeutic and devices sector to showcase their technology and have one-on-one sessions with investors and strategic partners. Each of the 14 companies was carefully chosen by an independent panel of experts, selected for strength of research, impact on cancer, product development and market potential. The event was beneficial to both small businesses.

  5. 78 FR 27974 - Proposed Collection; 60-Day Comment Request: National Cancer Institute (NCI) Alliance for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-13

    ...In compliance with the requirement of Section 3506(c)(2)(A) of the Paperwork Reduction Act of 1995, for opportunity for public comment on proposed data collection projects, the National Cancer Institute (NCI), National Institutes of Health (NIH), will publish periodic summaries of proposed projects to be submitted to the Office of Management and Budget (OMB) for review and approval. Written......

  6. Regulatory Anatomy

    PubMed Central

    2015-01-01

    This article proposes the term ‚Äúsafety logics‚ÄĚ to understand attempts within the European Union (EU) to harmonize member state legislation to ensure a safe and stable supply of human biological material for transplants and transfusions. With safety logics, I refer to assemblages of discourses, legal documents, technological devices, organizational structures, and work practices aimed at minimizing risk. I use this term to reorient the analytical attention with respect to safety regulation. Instead of evaluating whether safety is achieved, the point is to explore the types of ‚Äúsafety‚ÄĚ produced through these logics as well as to consider the sometimes unintended consequences of such safety work. In fact, the EU rules have been giving rise to complaints from practitioners finding the directives problematic and inadequate. In this article, I explore the problems practitioners face and why they arise. In short, I expose the regulatory anatomy of the policy landscape. PMID:26139952

  7. NCI at Frederick Employees Honored at NCI Director’s Awards Program | Poster

    Cancer.gov

    By Nancy Parrish, Staff Writer Nineteen staff members affiliated with NCI at Frederick or the Frederick National Laboratory for Cancer Research (FNLCR) were recognized at the 2014 NCI Director’s Award Ceremony for their outstanding contributions to advancing cancer research. The ceremony, held Dec. 1, took place at the NIH Natcher Conference Center, on the main campus in Bethesda.

  8. NCI at Frederick Employees Recognized at the 2013 NCI Director’s Awards Ceremony | Poster

    Cancer.gov

    By Andrea Frydl, Contributing Writer, and Ashley DeVine, Staff Writer More than 60 NCI at Frederick government and contractor employees were recognized at the NCI Director’s Awards Ceremony on Nov. 14, held on the main NIH campus in Bethesda.

  9. New Phone System Coming to NCI Campus at Frederick | Poster

    Cancer.gov

    By Travis Fouche and Trent McKee, Guest Writers Beginning in September, phones at the NCI Campus at Frederick will begin to be replaced, as the project to upgrade the current phone system ramps up. Over the next 16 months, the Information Systems Program (ISP) will be working with Facilities Maintenance and Engineering and Computer & Statistical Services to replace the current Avaya phone system with a Cisco Unified Communications phone system. The Cisco system is already in use at the Advanced Technology Research Facility (ATRF).

  10. Nail anatomy.

    PubMed

    de Berker, David

    2013-01-01

    The nail unit comprises the nail plate, the surrounding soft tissues, and their vasculature and innervation based upon the distal phalanx. The nail plate is a laminated keratinized structure lying on the nail matrix (15-25%), the nail bed with its distal onychodermal band (75-85%), and the hyponychium at its free edge. The distal part of the matrix, the lunula characterized by its half-moon shape, can be observed in some digits. The nail plate is embedded by the proximal and lateral folds. From the proximal nail fold, the cuticle (also known as the eponychium), adheres to the superficial surface of the proximal nail plate. The nail unit possesses a complex and abundant vascular network to ensure adequate blood supply. Finally, both the periungual soft tissues and the nail folds are innervated. The shapes, structure, and inter-relationships of these tissues are factors in the way nails present with disease and how we understand and manage those diseases. In particular, an understanding of the surgical anatomy is important for those undertaking diagnostic or curative operations on the nail. With this knowledge, the most appropriate surgery can be planned and the patient can be provided with accurate and clear guidance to enable informed consent. PMID:24079579

  11. NCIís Annual Report on Complementary and Alternative Medicine(CAM)- OCCAM

    Cancer.gov

    Contact Us | Sitemap CAM at the NCI NCI CAM History Highlights of NCI CAM Activities NCI CAM Annual Report Research Funding Opportunities Grant Application Information Research Resources Funded Research Research Results Training Opportunities FAQ's

  12. NCI Community Cancer Centers Program - Progress Reports and Tools

    Cancer.gov

    NCI Community Cancer Centers Program - Progress Reports and Tools Search NCCCP NCCCP Home About Focus Areas NCI in the Community News & Publications Contact About Overview For Patients and Public For Researchers NCCCP Progress Reports and Tools

  13. NCI Center of Excellence in Integrative Cancer Biology and Genomics

    Cancer.gov

    Participation CEICBG participation is open to all NCI intramural investigators who are interested in cancer biology or genomics. Membership Full membership, which includes a research listing on the CEICBG website, is open to all intramural NCI principal i

  14. Highlights from the 2014 NCI Intramural Scientific Retreat

    Cancer.gov

    In addition, Douglas Lowy, M.D., NCI Deputy Director, presented the 2014 NCI Directorís Innovation Awards, which are designed to support the development of novel approaches and technologies for accelerating cancer research.

  15. NCI Community Cancer Centers Program - Related Programs Overview

    Cancer.gov

    One or more of the NCCCPÔŅĹs four focus areas is shared by several NCI programs ÔŅĹ including the NCI Cancer Centers Program, Community Clinical Oncology Program, Community Network Program, and others. The NCCCP will incorporate best practices from other NCI community cancer programs in delivering services to these communities.

  16. NCI Community Cancer Centers Program - Related Programs Overview

    Cancer.gov

    One or more of the NCCCP's four focus areas is shared by several NCI programs including the NCI Cancer Centers Program, Community Clinical Oncology Program, Community Network Program, and others. The NCCCP will incorporate best practices from other NCI community cancer programs in delivering services to these communities.

  17. Spring 2009 Newsletter-Rare Plant Compounds from China Undergo Screening at NCI

    Cancer.gov

    In July 2008, the United States government signed a research agreement with China to foster collaboration between researchers studying integrative and Traditional Chinese Medicine (TCM) in both countries. One of the first and most promising of these projects is a partnership between the Kunming Institute of Botany (KIB) of China Academy of Sciences and two groups at the National Cancer Institute (NCI).

  18. Anatomy of the Eye

    MedlinePLUS

    ... Eye Terms Conditions Frequently Asked Questions Espa√Īol Condiciones Chinese Conditions Anatomy of the Eye En Espa√Īol Read in Chinese External (Extraocular) Anatomy Extraocular Muscles: There are six ...

  19. Normal Female Reproductive Anatomy

    MedlinePLUS

    ... My Pictures Browse Search Quick Search Image Details Reproductive System, Female, Anatomy View/Download: Small: 720x756 View Download Add ... Reproductive System, Female, Anatomy Description: Anatomy of the female reproductive system; drawing shows the uterus, myometrium (muscular outer layer ...

  20. NCI Training and Career Development Inventory

    Cancer.gov

    Office of the Director, NCI DCP CCR DCEG DCCPS DEA DCTD DCB OD OD 2. Organ Systems Branch (SPORES) 3. Cancer Training Branch (CTB) 4. Comprehensive Minority Biomedical Branch (CMBB) 6. Office of Training and Education 5. Office of Preventive Oncology 7. Office of Education 1.

  1. NCI Outstanding Investigator Award - 2015 Recipients

    Cancer.gov

    NCI announced availability of the 2015 Outstanding Investigator Award in late 2014. Below are profiles of recipients of the 2015 Award made to date. All 2015 Awards are expected to be made by the end of the year and will be added to this web page. Congratulations

  2. NCI: SBIR & STTR - News & Events - Recent Events

    Cancer.gov

    This session provided an overview of the SBIR and STTR Programs and current funding opportunities for innovative biomedical technologies. The presentation included updates on new initiatives at the NCI SBIR Development Center, and practical strategies and tips for developing successful and competitive proposals.

  3. NCI and Leidos Play Ball | Poster

    Cancer.gov

    By Carolynne Keenan, Contributing Writer The ping of an aluminum bat off a ball or the thump of a pop-up fly ball caught in a glove are two sounds familiar to baseball fans. Slow-pitch softball sounds‚ÄĒlike those in the August game between mixed teams of NCI and Leidos Biomedical Research (formerly SAIC-Frederick) players‚ÄĒare similar.

  4. 2009 NCI Cohort Consortium Annual Meeting

    Cancer.gov

    The NCI Cohort Consortium celebrated its 10th anniversary at its annual meeting held on November 5, 2009, in Bethesda, MD. The meeting was sponsored by the Division of Cancer Control and Population Sciences (DCCPS) and the Division of Cancer Epidemiology and Genetics (DCEG).

  5. NCI Cancer Health Disparities Interest Group

    Cancer.gov

    Across all of the major lethal cancers, disparities in the incidence and/or survival, of cancer patients by race is evident. While some of the causes have been determined, most remain unexplored and undefined. There are a number of investigators at NCI, f

  6. At NCI, Supporting the Best Science

    Cancer.gov

    Yesterday, at the AACR annual meeting, Dr. Doug Lowy spoke directly to the research community about his goals as NCI Acting Director. Dr. Lowy said that he plans to continue many of the programs launched by his predecessor, Dr. Harold Varmus, and to sharp

  7. Discovery | NCI Experimental Therapeutics (NExT)

    Cancer.gov

    Sanford-Burnham Medical Research Institute is one of seven NCI-designated basic research Cancer Centers. The Institute is among the world leaders in areas of fundamental interest to anti-cancer drug discovery, including studies focusing on mechanisms of cell survival and cell death, cell motility, invasion and angiogenesis, cell stress and intracellular signaling.

  8. NCI Genitourinary Malignancies Center of Excellence

    Cancer.gov

    Participation GUM-COE participation is open to all NCI intramural staff who are interested in GU cancers. Membership Full membership, which includes a research listing on the GUM-COE website, is open to all CCR Principal Investigators and Senior Scientist

  9. Bylaws of the NCI Cohort Consortium

    Cancer.gov

    The NCI Cohort Consortium has the potential to foster the development of young investigators in cancer epidemiology as well as to develop collaborations and strategic partnerships with other like-minded organizations and initiatives to foster greater scientific innovation, productivity, efficiency, and synergy.

  10. NCI scientists identify new inflammatory syndrome

    Cancer.gov

    NCI scientists have identified a new inflammatory condition called interleukin-6 syndrome caused by Kaposiís sarcoma-associated herpesvirus (KSHV) in some people with HIV/AIDS. This syndrome will be added to three existing types of KSHV-linked illnesses i

  11. NCI International EBV-Gastric Cancer Consortium

    Cancer.gov

    A collaboration among NCI and extramural investigators, established by DCEG in 2006, that utilizes data and biospecimens from completed and ongoing case series and observational studies of gastric cancer to replicate and extend findings from previous studies hindered by small numbers of EBV-positive cases, and to stimulate multidisciplinary research in this area.

  12. Mission & Role | NCI Technology Transfer Center | TTC

    Cancer.gov

    The NCI TTC serves as the focal point for implementing the Federal Technology Transfer Act to utilize patents as incentive for commercial development of technologies and to establish research collaborations and licensing among academia, federal laboratories, non-profit organizations, and industry.

  13. License Agreements | NCI Technology Transfer Center | TTC

    Cancer.gov

    Since the government cannot engage in the development, manufacture, and sale of products, the NCI Technology Transfer Center (TTC) makes its discoveries (and discoveries from nine other NIH Institutes) available to organizations that can assist in the further development and commercialization of these basic science discoveries, to convert them into public health benefits.

  14. NCI/DCCPS R21 Program Announcements

    Cancer.gov

    The Division of Cancer Control and Population Sciences funds a large portfolio of grants and contracts. The portfolio currently includes approximately 800 grants valued at nearly $450 million. Here we provide a listing of funding opportunities that are currently accepting applications. Please visit this page regularly as new funding opportunities are added upon approval by NCI.

  15. NCI Approves Funding Plan for NCI Community Oncology Research Program (NCORP) | Division of Cancer Prevention

    Cancer.gov

    On June 24, 2014, the Scientific Program Leaders (SPL) of the National Cancer Institute (NCI) approved the funding plan for the†NCI Community Oncology Research Program (NCORP), a national network of investigators, cancer care providers, academic institutions, and other organizations. NCORP will conduct multi-site cancer clinical trials and studies in diverse populations in community-based healthcare systems across the United States. The program will receive $93 million a year for five years. |

  16. NCI Approves Funding Plan for NCI Community Oncology Research Program (NCORP) | Division of Cancer Prevention

    Cancer.gov

    On June 24, 2014, the Scientific Program Leaders (SPL) of the National Cancer Institute (NCI) approved the funding plan for the NCI Community Oncology Research Program (NCORP), a national network of investigators, cancer care providers, academic institutions, and other organizations. NCORP will conduct multi-site cancer clinical trials and studies in diverse populations in community-based healthcare systems across the United States. The program will receive $93 million a year for five years. |

  17. The quail anatomy portal.

    PubMed

    Ruparelia, Avnika A; Simkin, Johanna E; Salgado, David; Newgreen, Donald F; Martins, Gabriel G; Bryson-Richardson, Robert J

    2014-01-01

    The Japanese quail is a widely used model organism for the study of embryonic development; however, anatomical resources are lacking. The Quail Anatomy Portal (QAP) provides 22 detailed three-dimensional (3D) models of quail embryos during development from embryonic day (E)1 to E15 generated using optical projection tomography. The 3D models provided can be virtually sectioned to investigate anatomy. Furthermore, using the 3D nature of the models, we have generated a tool to assist in the staging of quail samples. Volume renderings of each stage are provided and can be rotated to allow visualization from multiple angles allowing easy comparison of features both between stages in the database and between images or samples in the laboratory. The use of JavaScript, PHP and HTML ensure the database is accessible to users across different operating systems, including mobile devices, facilitating its use in the laboratory.The QAP provides a unique resource for researchers using the quail model. The ability to virtually section anatomical models throughout development provides the opportunity for researchers to virtually dissect the quail and also provides a valuable tool for the education of students and researchers new to the field. DATABASE URL: http://quail.anatomyportal.org (For review username: demo, password: quail123). PMID:24715219

  18. The anatomy of a World Wide Web library service: the BONES demonstration project. Biomedically Oriented Navigator of Electronic Services.

    PubMed Central

    Schnell, E H

    1995-01-01

    In 1994, the John A. Prior Health Sciences Library at Ohio State University began to develop a World Wide Web demonstration project, the Biomedically Oriented Navigator of Electronic Services (BONES). The initial intent of BONES was to facilitate the health professional's access to Internet resources by organizing them in a systematic manner. The project not only met this goal but also helped identify the resources needed to launch a full-scale Web library service. This paper discusses the tasks performed and resources used in the development of BONES and describes the creation and organization of documents on the BONES Web server. The paper also discusses the outcomes of the project and the impact on the library's staff and services. PMID:8547903

  19. NCI-Frederick PHL - Embryology

    Cancer.gov

    Orientation for microtomy can be tailored to the project, typically embryos are embedded in the sagittal plane for a rapid assessment of the entire embryo. For early stage embryos, serial sections through the entire embryo provide an efficient method of surveying the entire embryo. Larger embryos can be effectively surveyed by stepping through the tissue at predetermined points.

  20. NCI at Frederick Ebola Response Team | Poster

    Cancer.gov

    Editor‚Äôs note: This article was adapted from the Employee Diversity Team‚Äôs display case exhibit ‚ÄúRecognizing the NCI at Frederick Ebola Response Team,‚ÄĚ in the lobby of Building 549. The Poster staff recognizes that this article does not include everyone who was involved in the response to the Ebola crisis, both at NCI at Frederick and in Africa. When the Ebola crisis broke out in 2014 in West Africa, staff members from the Frederick National Laboratory for Cancer Research responded quickly. Members of the Clinical Monitoring Research Program (CMRP) were instrumental not only in setting up the clinical trials of the vaccine in Liberia, but also in providing training, community outreach, and recruitment strategies for the trials.

  1. NCI-Frederick PHL - Molecular Pathology

    Cancer.gov

    The Molecular Pathology Group (MPG) is a recent addition to the laboratory Animal Science Program (LASP), at the Frederick, Maryland campus of the National Cancer Institute. This Leidos Biomedical Research, Inc. group is actively working to expand high-quality, pathology-based research application support available to NCI investigators and their collaborators. Its primary role is to extend the capabilities of the existing Leidos Biomedical Research, Inc.

  2. Help Finding NCI-Supported Clinical Trials

    Cancer.gov

    This page explains how to use the clinical trials search form to find NCI-supported clinical trials and review the results of your searches. It is helpful to gather as much information as possible before a search. Information such as the specific type and stage of cancer, the type of trial that might be relevant (treatment, diagnostic, supportive care), and other details about the patient will be helpful.

  3. Of mice and men: aligning mouse and human anatomies.

    PubMed

    Bodenreider, Olivier; Hayamizu, Terry F; Ringwald, Martin; De Coronado, Sherri; Zhang, Songmao

    2005-01-01

    This paper reports on the alignment between mouse and human anatomies, a critical resource for comparative science as diseases in mice are used as mod-els of human disease. The two ontologies under investigation are the NCI Thesaurus (human anatomy) and the Adult Mouse Anatomical Dictionary, each comprising about 2500 anatomical concepts. This study compares two approaches to aligning ontologies. One is fully automatic, based on a combination of lexical and structural similarity; the other is manual. The resulting mappings were evaluated by an expert. 715 and 781 mappings were identified by each method respectively, of which 639 are common to both and all valid. The applications of the map-ping are discussed from the perspective of biology and from that of ontology. PMID:16779002

  4. Anatomy Comic Strips

    ERIC Educational Resources Information Center

    Park, Jin Seo; Kim, Dae Hyun; Chung, Min Suk

    2011-01-01

    Comics are powerful visual messages that convey immediate visceral meaning in ways that conventional texts often cannot. This article's authors created comic strips to teach anatomy more interestingly and effectively. Four-frame comic strips were conceptualized from a set of anatomy-related humorous stories gathered from the authors' collective…

  5. Anatomy Comic Strips

    ERIC Educational Resources Information Center

    Park, Jin Seo; Kim, Dae Hyun; Chung, Min Suk

    2011-01-01

    Comics are powerful visual messages that convey immediate visceral meaning in ways that conventional texts often cannot. This article's authors created comic strips to teach anatomy more interestingly and effectively. Four-frame comic strips were conceptualized from a set of anatomy-related humorous stories gathered from the authors' collectiveÖ

  6. Halaven¬ģ - eribulin mesylate (analog of halichondrin B) | NCI Technology Transfer Center | TTC

    Cancer.gov

    Under a CRADA with NCI, Eisai Co. provided eribulin for NCI's preclinical development activities and to support NCI's Phase I clinical trials. Eisai ultimately took the product, Halaven¬ģ, to licensure.

  7. Anatomy comic strips.

    PubMed

    Park, Jin Seo; Kim, Dae Hyun; Chung, Min Suk

    2011-01-01

    Comics are powerful visual messages that convey immediate visceral meaning in ways that conventional texts often cannot. This article's authors created comic strips to teach anatomy more interestingly and effectively. Four-frame comic strips were conceptualized from a set of anatomy-related humorous stories gathered from the authors' collective imagination. The comics were drawn on paper and then recreated with digital graphics software. More than 500 comic strips have been drawn and labeled in Korean language, and some of them have been translated into English. All comic strips can be viewed on the Department of Anatomy homepage at the Ajou University School of Medicine, Suwon, Republic of Korea. The comic strips were written and drawn by experienced anatomists, and responses from viewers have generally been favorable. These anatomy comic strips, designed to help students learn the complexities of anatomy in a straightforward and humorous way, are expected to be improved further by the authors and other interested anatomists. PMID:21634024

  8. Discovery | NCI Experimental Therapeutics (NExT)

    Cancer.gov

    The University of Minnesota Chemical Diversity Center is based primarily on the capabilities of the Institute for Therapeutics Discovery and Development (ITDD) and the Department of Medicinal Chemistry in collaboration with the NCI-designated Masonic Comprehensive Cancer Center, the College of Pharmacy, the Center for Translational Medicine, and the Minnesota Supercomputing Institute. The University of Minnesota Chemical Diversity Centerís research focus is the discovery and development of anticancer agents, using stateof-the-art chemical, biological, computational, pharmacological and imaging approaches.

  9. Extramural NCI Data Access Committee: Charter

    Cancer.gov

    The Extramural National Cancer Institute (NCI) Data Access Committee (DAC) will review and approve or disapprove all requests from the research community for access to controlled data of genome-wide association studies (GWAS) of cancer and other genotype-phenotype studies (including sequencing and molecular diagnostic assays) for which it is responsible. The Committee evaluates if the request conforms to NIH policies and procedures including consistency of the proposed research use with data use limitations stipulated by the submitting institution for each study.

  10. METAvivor Reps Visit NCI at Frederick | Poster

    Cancer.gov

    Three representatives of METAvivor visited NCI at Frederick on April 13 to meet and tour with Balamurugan Kuppusamy, Ph.D., staff scientist in the laboratory of Esta Sterneck, Ph.D., senior investigator, Laboratory of Cell and Developmental Signaling, Center for Cancer Research.  The purpose of the visit was to learn more about Kuppusamy’s research. Kuppusamy is a recipient of a $50,000, two-year grant awarded by METAvivor to study the role of the CEBPD-FBXW7 signaling pathway in inflammatory breast cancer.

  11.              NCI Ethics

    Cancer.gov

    September 2012 NCI ETHICS OFFICE UPDATES Office of Ethics to Welcome New Director       Effective October 7, 2012, the NCI Office of Ethics welcomes Nancy O’Hanlon as its Director and Deputy Ethics Counselor.Nancy was most recently the Director of the Eth

  12. NCI Community Oncology Research Program Approved | Division of Cancer Prevention

    Cancer.gov

    On June 24, 2013, the National Cancer Institute (NCI) Board of Scientific Advisors approved the creation of the NCI Community Oncology Research Program (NCORP). NCORP will bring state-of-the art cancer prevention, control, treatment and imaging clinical trials, cancer care delivery research, and disparities studies to individuals in their own communities. |

  13.              NCI Ethics

    Cancer.gov

    STORY:  Sharing resources, research and ideas are fundamental to the National Cancer Institute’s (NCI) mission. Many NCI employees are invited to participate in activities outside of typical job duties, such as teaching a class at a university or editing

  14. NCI Community Oncology Research Program Approved | Division of Cancer Prevention

    Cancer.gov

    On June 24, 2013, the National Cancer Institute (NCI) Board of Scientific Advisors approved the creation of the NCI Community Oncology Research Program (NCORP). NCORP will bring state-of-the art cancer prevention, control, treatment and imaging clinical trials, cancer care delivery research, and disparities studies to individuals in their own communities.

  15. Implementation of the NCIís National Clinical Trials Network

    Cancer.gov

    NCI is launching a new clinical trials research network intended to improve treatment for the more than 1.6 million Americans diagnosed with cancer each year. The new system, NCIís National Clinical Trials Network (NCTN), will facilitate the rapid initia

  16. The Employee Invention Report (EIR) | NCI Technology Transfer Center | TTC

    Cancer.gov

    After making such a discovery, NCI researchers should immediately contact their Laboratory or Branch Chief and inform him or her of a possible invention and consult with your NCI TTC Technology Transfer Specialist about submitting an Employee Invention Report (EIR) Form.

  17. Skull Base Anatomy.

    PubMed

    Patel, Chirag R; Fernandez-Miranda, Juan C; Wang, Wei-Hsin; Wang, Eric W

    2016-02-01

    The anatomy of the skull base is complex with multiple neurovascular structures in a small space. Understanding all of the intricate relationships begins with understanding the anatomy of the sphenoid bone. The cavernous sinus contains the carotid artery and some of its branches; cranial nerves III, IV, VI, and V1; and transmits venous blood from multiple sources. The anterior skull base extends to the frontal sinus and is important to understand for sinus surgery and sinonasal malignancies. The clivus protects the brainstem and posterior cranial fossa. A thorough appreciation of the anatomy of these various areas allows for endoscopic endonasal approaches to the skull base. PMID:26614826

  18. Comparison of a Gross Anatomy Laboratory to Online Anatomy Software for Teaching Anatomy

    ERIC Educational Resources Information Center

    Mathiowetz, Virgil; Yu, Chih-Huang; Quake-Rapp, Cindee

    2016-01-01

    This study was designed to assess the grades, self-perceived learning, and satisfaction between occupational therapy students who used a gross anatomy laboratory versus online anatomy software (AnatomyTV) as tools to learn anatomy at a large public university and a satellite campus in the mid-western United States. The goal was to determine ifÖ

  19. Comparison of a Gross Anatomy Laboratory to Online Anatomy Software for Teaching Anatomy

    ERIC Educational Resources Information Center

    Mathiowetz, Virgil; Yu, Chih-Huang; Quake-Rapp, Cindee

    2016-01-01

    This study was designed to assess the grades, self-perceived learning, and satisfaction between occupational therapy students who used a gross anatomy laboratory versus online anatomy software (AnatomyTV) as tools to learn anatomy at a large public university and a satellite campus in the mid-western United States. The goal was to determine if…

  20. Anatomy of the Brain

    MedlinePLUS

    ... as how we function in our environment. The diagrams below show brain anatomy, or the various parts ... and spine, as well as how they work, will help you understand the symptoms of brain tumors, how ...

  1. Evidence-Based Anatomy

    PubMed Central

    Yammine, Kaissar

    2014-01-01

    Anatomy is a descriptive basic medical science that is no longer considered a research-led discipline. Many publications in clinical anatomy are prevalence studies treating clinically relevant anatomical variations and reporting their frequencies and/or associations with variables such as age, sex, side, laterality, and ancestry. This article discusses the need to make sense of the available literature. A new concept, evidence-based anatomy (EBA), is proposed to find, appraise, and synthetize the results reported in such publications. It consists in applying evidence-based principles to the field of epidemiological anatomy research through evidence synthesis using systematic reviews and meta-analyses to generate weighted pooled results. Pooled frequencies and associations based on large pooled sample size are likely to be more accurate and to reflect true population statistics and associations more closely. A checklist of a typical systematic review in anatomy is suggested and the implications of EBA for practice and future research, along with its scope, are discussed. The EBA approach would have positive implications for the future preservation of anatomy as a keystone basic science, for sound knowledge of anatomical variants, and for the safety of medical practice. Clin. Anat. 27:847Ė852, 2014. PMID:24797314

  2. NCI at Frederick Contributes to Feds Feed Families | Poster

    Cancer.gov

    Once again, NCI at Frederick participated in the annual Feds Feed Families event, which challenges federal workers to help knock out hunger with a food drive. This year, NIH collected 26,315 pounds of non-perishable goods, beating its goal of collecting 20,000 pounds. This includes over four tons of food that was collected at satellite locations, including NCI at Frederick. The food collected at NCI at Frederick was donated locally to the Frederick Rescue Mission. These donations help feed local families in need through the holiday season.

  3. Ontology-enriched Visualization of Human Anatomy

    SciTech Connect

    Pouchard, LC

    2005-12-20

    The project focuses on the problem of presenting a human anatomical 3D model associated with other types of human systemic information ranging from physiological to anatomical information while navigating the 3D model. We propose a solution that integrates a visual 3D interface and navigation features with the display of structured information contained in an ontology of anatomy where the structures of the human body are formally and semantically linked. The displayed and annotated anatomy serves as a visual entry point into a patient's anatomy, medical indicators and other information. The ontology of medical information provides labeling to the highlighted anatomical parts in the 3D display. Because of the logical organization and links between anatomical objects found in the ontology and associated 3D model, the analysis of a structure by a physician is greatly enhanced. Navigation within the 3D visualization and between this visualization and objects representing anatomical concepts within the model is also featured.

  4. Contemporary art and the ethics of anatomy.

    PubMed

    Barilan, Y Michael

    2007-01-01

    The ethics of anatomy bears on the ways in which we present and behold human bodies and human remains, as well as on the duties we have with regard to the persons whose bodies or body parts are presented. Anatomy is also a mode of thought and of social organization. Following Merleau-Ponty's assertion that the human body belongs both to the particular and to the metaphysical, I contend that art's ways of rendering of the particular in human anatomy often bring into relief metaphysical and ethical insights relevant to clinical medicine. This paper discusses the art of Gideon Gechtman, Mary Ellen Mark, Shari Zolla, and Christine Borland. It considers the relationship of these artists to earlier artistic traditions and the implications of their work for contemporary medicine and the biopsychosocial paradigm. Andrew Wyeth, the Visible Male Project, the Isenheim Altarpiece by GrA(1/4)newald, and an anonymous Dutch Baroque portrait are also discussed. PMID:17259679

  5. 2013 FRIENDS-OF-NCI-EGRP News Flashes

    Cancer.gov

    An archive of listserv announcements sent by the Epidemiology and Genetics Research Program to FRIENDS-OF-NCI-EGRP LISTSERV subscribers to communicate information about funding opportunities, grantsmanship issues, research resources, and other relevant news.

  6. 2014 FRIENDS-OF-NCI-EGRP News Flashes

    Cancer.gov

    An archive of listserv announcements sent by the Epidemiology and Genetics Research Program to FRIENDS-OF-NCI-EGRP LISTSERV subscribers to communicate information about funding opportunities, grantsmanship issues, research resources, and other relevant news.

  7. 2010 FRIENDS-OF-NCI-EGRP News Flashes

    Cancer.gov

    A 2010 archive of listserv announcements sent by the Epidemiology and Genetics Research Program to FRIENDS-OF-NCI-EGRP LISTSERV subscribers to communicate information about funding opportunities, grantsmanship issues, research resources, and other relevant news.

  8. Centro para la Salud Mundial (CGH) del NCI

    Cancer.gov

    El Centro para la Salud Mundial (CGH) del NCI coordina actividades de investigación y trabaja con socios nacionales e internacionales para comprender y enfrentar la carga que representa el cáncer a nivel mundial.

  9. 2009 FRIENDS-OF-NCI-EGRP News Flashes

    Cancer.gov

    A 2009 archive of listserv announcements sent by the Epidemiology and Genetics Research Program to FRIENDS-OF-NCI-EGRP LISTSERV subscribers to communicate information about funding opportunities, grantsmanship issues, research resources, and other relevant news.

  10. NCI Center of Excellence in Integrative Cancer Biology and Genomics

    Cancer.gov

    Highlighted Article 1 The Center of Excellence in Integrative Cancer Biology and Genomics (CEICBG) is one of four Centers of Excellence established within the NCI Intramural Research Program (IRP). The Centers of Excellence build upon existing structures

  11. Micatu Tissue Arrayer | NCI Technology Transfer Center | TTC

    Cancer.gov

    An NCI researcher recognized a critical need to create a low-cost, easy-to-use tissue microarrayer (TMA), an instrument used by researchers and pathologists to accurately examine tissue samples from patients.

  12. NCI at ASCO: A brief overview on women's cancers

    Cancer.gov

    The 2014 annual American Society of Clinical Oncology (ASCO) meeting in Chicago in June highlighted results from a number of NCI-supported and -sponsored clinical trial results in women’s cancers. Taken together, these results represent important advances

  13. NCI scientists at forefront of new prostate cancer diagnostics

    Cancer.gov

    Introduction of the UroNav was the result of nearly a decadeís research and development, principally conducted at NCI. Resembling a stylized computer workstation on wheels, the system electronically fuses together pictures from magnetic resonance imaging

  14. 2008 FRIENDS-OF-NCI-EGRP News Flashes

    Cancer.gov

    A 2008 archive of listserv announcements sent by the Epidemiology and Genetics Research Program to FRIENDS-OF-NCI-EGRP LISTSERV subscribers to communicate information about funding opportunities, grantsmanship issues, research resources, and other relevant news.

  15. NCI Requests Cancer Targets for Monoclonal Antibody Production and Characterization

    Cancer.gov

    In an effort to provide well-characterized monoclonal antibodies to the scientific community, NCI's Antibody Characterization Program requests cancer-related protein targets for affinity production and distribution.

  16. First NCI Epidemiology Leadership Workshop: Tobacco, Diet, and Genes

    Cancer.gov

    Skip to Main Content at the National Institutes of Health | www.cancer.gov Epidemiology and Genomics Research In NCI's Division of Cancer Control and Population Sciences Search EGRP: Main Menu EGRP Home About the Program Mission & Vision Organizational

  17. NCI - Board of Scientific Acvisors - 19JUN97 Meeting

    Cancer.gov

    TABLE OF CONTENTS Call to Order and Opening Remarks - Dr. David Livingston Consideration of March Meeting Minutes - Dr. David Livingston Report of the Director, NCI - Dr. Richard Klausner Congressional Update - Ms. Dorothy Tisevich Ongoing and New Business - Dr.

  18. NCI Director Also to Be Interim FDA Commissioner

    Cancer.gov

    Andrew von Eschenbach, M.D., director of the NCI, was asked by President Bush on Friday, September 23, 2005, to assume the additional role of interim Commissioner of the U.S. Food and Drug Administration (FDA).

  19. NCI Management of Radiation Studies - September 16, 1998

    Cancer.gov

    "NCI Management of Radiation Studies" Statement of Richard D. Klausner, M.D., Director National Cancer Institute National Institutes of Health Department Of Health And Human Services Before the Senate Committee On Governmental Affairs Permanent

  20. NCI and the Precision Medicine Initiative¬ģ

    Cancer.gov

    NCI's activities related to precision medicine focuses on new and expanded precision medicine clinical trials; mechanisms to overcome drug resistance to cancer treatments; and developing a shared digital repository of precision medicine trials data.

  1. Líneas Vitales: Programas y servicios del NCI

    Cancer.gov

    Artículos y videos sobre los programas y servicios del Instituto Nacional del Cáncer de la serie educativa Líneas Vitales del NCI, la cual está dirigida especialmente a poblaciones multiculturales.

  2. 2012 FRIENDS-OF-NCI-EGRP News Flashes

    Cancer.gov

    A 2012 archive of listserv announcements sent by the Epidemiology and Genetics Research Program to FRIENDS-OF-NCI-EGRP LISTSERV subscribers to communicate information about funding opportunities, grantsmanship issues, research resources, and other relevant news.

  3. NCI Community Oncology Research Program (NCORP) | Division of Cancer Prevention

    Cancer.gov

    The NCI Community Oncology Research Program (NCORP) is a national network of cancer care investigators, providers, academia, and other organizations that care for diverse populations in health systems. View the list of publications from NCORP.

  4. NCI Initiative to Speed Development of Childhood Cancer Therapies

    Cancer.gov

    NCI has awarded grants to five research teams to participate in its Pediatric Preclinical Testing Consortium, which is intended to help to prioritize which agents to pursue in pediatric clinical trials.

  5. NCI Alliance for Nanotechnology in Cancer - Alliance in the News

    Cancer.gov

    The NCI Alliance for Nanotechnology in Cancer is conducting cutting-edge research using nanotechnology to transform the diagnosis, prevention, treatment, and clinical outcomes for cancer patients. Read news stories and announcements below about the Alliance's multidisciplinary work.

  6. 2011 FRIENDS-OF-NCI-EGRP News Flashes

    Cancer.gov

    A 2011 archive of listserv announcements sent by the Epidemiology and Genetics Research Program to FRIENDS-OF-NCI-EGRP LISTSERV subscribers to communicate information about funding opportunities, grantsmanship issues, research resources, and other relevant news.

  7. How To Apply | NCI Experimental Therapeutics (NExT)

    Cancer.gov

    Please note that a NExT proposal is NOT a grant application. Rather, a NExT proposal is an application to gain access to scientific capabilities and resources available to the NCI with the goal of moving promising anti-cancer concepts and novel agents into clinical testing. Applications to the NExT Program are evaluated for scientific merit, feasibility, novelty, clinical need, and alignment with NCI mission.

  8. NCI CAM News Fall 2007, Vol 1, Issue 1

    Cancer.gov

    Vol.1 - Issue 1 Established in October 1998, OCCAM is responsible for NCIís growing research agenda in CAM as it relates to cancer prevention, treatment, symptom management, and rehabilitation. OCCAM also acts as NCIís primary link to CAM communities and cancer researchers regarding CAM and cancer. OCCAM is directed by Dr. Jeffrey D. White, a medical oncologist with a background in laboratory and clinical cancer research.

  9. Invention Development Program Helps Nurture NCI at Frederick Technologies | Poster

    Cancer.gov

    The Invention Development Fund (IDF) was piloted by the Technology Transfer Center (TTC) in 2014 to facilitate the commercial development of NCI technologies. The IDF received a second round of funding from the NCI Office of the Director and the Office of Budget and Management to establish the Invention Development Program (IDP) for fiscal year 2016. The IDP is using these funds to help advance a second set of inventions.

  10. Learning Anatomy Enhances Spatial Ability

    ERIC Educational Resources Information Center

    Vorstenbosch, Marc A. T. M.; Klaassen, Tim P. F. M.; Donders, A. R. T.; Kooloos, Jan G. M.; Bolhuis, Sanneke M.; Laan, Roland F. J. M.

    2013-01-01

    Spatial ability is an important factor in learning anatomy. Students with high scores on a mental rotation test (MRT) systematically score higher on anatomy examinations. This study aims to investigate if learning anatomy also oppositely improves the MRT-score. Five hundred first year students of medicine ("n" = 242, intervention) and…

  11. Learning Anatomy Enhances Spatial Ability

    ERIC Educational Resources Information Center

    Vorstenbosch, Marc A. T. M.; Klaassen, Tim P. F. M.; Donders, A. R. T.; Kooloos, Jan G. M.; Bolhuis, Sanneke M.; Laan, Roland F. J. M.

    2013-01-01

    Spatial ability is an important factor in learning anatomy. Students with high scores on a mental rotation test (MRT) systematically score higher on anatomy examinations. This study aims to investigate if learning anatomy also oppositely improves the MRT-score. Five hundred first year students of medicine ("n" = 242, intervention) andÖ

  12. SOP: Thawing, Propagation and Cryopreservation of NCI-PBCF-CCL256.1 (NCI-BL2126)

    Cancer.gov

    NCI-PBCF-CCL256.1 (NCI-BL2126) ............................................................................................................3 3. REAGENTS ...........................................................................................................................................5 A. PREPARATION OF COMPLETE GROWTH MEDIUM......................................................................................6 4. THAWING AND PROPAGATION OF CELLS ......................................................................................6 A. THAWING CELLS ...................................................................................................................................6 B. PROPAGATING CELLS ...........................................................................................................................7 C. SUBCULTURING CELLS ..........................................................................................................................8 5. HARVESTING OF CELLS FOR CRYOPRESERVATION ....................................................................9 6. CRYOPRESERVATION OF CELLS .................................................................................................. 10 A. CRYOPRESERVATION USING A RATE-CONTROLLED PROGRAMMABLE FREEZER ...................................... 10 i. Using the Cryomed ..................................................................................................................... 10 B. CRYOPRESERVATION USING ďM R. FROSTYĒ ........................................................................................ 11 7.

  13. Illustrated Speech Anatomy.

    ERIC Educational Resources Information Center

    Shearer, William M.

    Written for students in the fields of speech correction and audiology, the text deals with the following: structures involved in respiration; the skeleton and the processes of inhalation and exhalation; phonation and pitch, the larynx, and esophageal speech; muscles involved in articulation; muscles involved in resonance; and the anatomy of the…

  14. Anatomy for Biomedical Engineers

    ERIC Educational Resources Information Center

    Carmichael, Stephen W.; Robb, Richard A.

    2008-01-01

    There is a perceived need for anatomy instruction for graduate students enrolled in a biomedical engineering program. This appeared especially important for students interested in and using medical images. These students typically did not have a strong background in biology. The authors arranged for students to dissect regions of the body thatÖ

  15. The Anatomy Puzzle Book.

    ERIC Educational Resources Information Center

    Jacob, Willis H.; Carter, Robert, III

    This document features review questions, crossword puzzles, and word search puzzles on human anatomy. Topics include: (1) Anatomical Terminology; (2) The Skeletal System and Joints; (3) The Muscular System; (4) The Nervous System; (5) The Eye and Ear; (6) The Circulatory System and Blood; (7) The Respiratory System; (8) The Urinary System; (9) The…

  16. Illustrated Speech Anatomy.

    ERIC Educational Resources Information Center

    Shearer, William M.

    Written for students in the fields of speech correction and audiology, the text deals with the following: structures involved in respiration; the skeleton and the processes of inhalation and exhalation; phonation and pitch, the larynx, and esophageal speech; muscles involved in articulation; muscles involved in resonance; and the anatomy of theÖ

  17. The Anatomy Puzzle Book.

    ERIC Educational Resources Information Center

    Jacob, Willis H.; Carter, Robert, III

    This document features review questions, crossword puzzles, and word search puzzles on human anatomy. Topics include: (1) Anatomical Terminology; (2) The Skeletal System and Joints; (3) The Muscular System; (4) The Nervous System; (5) The Eye and Ear; (6) The Circulatory System and Blood; (7) The Respiratory System; (8) The Urinary System; (9) TheÖ

  18. Design and Development of a New Facility for Teaching and Research in Clinical Anatomy

    ERIC Educational Resources Information Center

    Greene, John Richard T.

    2009-01-01

    This article discusses factors in the design, commissioning, project management, and intellectual property protection of developments within a new clinical anatomy facility in the United Kingdom. The project was aimed at creating cost-effective facilities that would address widespread concerns over anatomy teaching, and support other activitiesÖ

  19. Design and Development of a New Facility for Teaching and Research in Clinical Anatomy

    ERIC Educational Resources Information Center

    Greene, John Richard T.

    2009-01-01

    This article discusses factors in the design, commissioning, project management, and intellectual property protection of developments within a new clinical anatomy facility in the United Kingdom. The project was aimed at creating cost-effective facilities that would address widespread concerns over anatomy teaching, and support other activities…

  20. An NCI perspective on creating sustainable biospecimen resources.

    PubMed

    Vaught, Jimmie; Rogers, Joyce; Myers, Kimberly; Lim, Mark David; Lockhart, Nicole; Moore, Helen; Sawyer, Sherilyn; Furman, Jeffrey L; Compton, Carolyn

    2011-01-01

    High-quality biospecimens with appropriate clinical annotation are critical in the era of personalized medicine. It is now widely recognized that biospecimen resources need to be developed and operated under established scientific, technical, business, and ethical/legal standards. To date, such standards have not been widely practiced, resulting in variable biospecimen quality that may compromise research efforts. The National Cancer Institute (NCI) Office of Biorepositories and Biospecimen Research (OBBR) was established in 2005 to coordinate NCI's biospecimen resource activities and address those issues that affect access to the high-quality specimens and data necessary for its research enterprises as well as the broader translational research field. OBBR and the NCI Biorepository Coordinating Committee developed NCI's "Best Practices for Biospecimen Resources" after consultation with a broad array of experts. A Biospecimen Research Network was established to fund research to develop additional evidence-based practices. Although these initiatives will improve the overall availability of high-quality specimens and data for cancer research, OBBR has been authorized to implement a national biobanking effort, cancer HUman Biobank (caHUB). caHUB will address systematically the gaps in knowledge needed to improve the state-of-the-science and strengthen the standards for human biobanking. This commentary outlines the progressive efforts by NCI in technical, governance, and economic considerations that will be important as the new caHUB enterprise is undertaken. PMID:21672889

  1. Human ocular anatomy.

    PubMed

    Kels, Barry D; Grzybowski, Andrzej; Grant-Kels, Jane M

    2015-01-01

    We review the normal anatomy of the human globe, eyelids, and lacrimal system. This contribution explores both the form and function of numerous anatomic features of the human ocular system, which are vital to a comprehensive understanding of the pathophysiology of many oculocutaneous diseases. The review concludes with a reference glossary of selective ophthalmologic terms that are relevant to a thorough understanding of many oculocutaneous disease processes. PMID:25704934

  2. [Anatomy of the skull].

    PubMed

    P√°sztor, Emil

    2010-01-01

    The anatomy of the human body based on a special teleological system is one of the greatest miracles of the world. The skull's primary function is the defence of the brain, so every alteration or disease of the brain results in some alteration of the skull. This analogy is to be identified even in the human embryo. Proportions of the 22 bones constituting the skull and of sizes of sutures are not only the result of the phylogeny, but those of the ontogeny as well. E.g. the age of the skeletons in archaeological findings could be identified according to these facts. Present paper outlines the ontogeny and development of the tissues of the skull, of the structure of the bone-tissue, of the changes of the size of the skull and of its parts during the different periods of human life, reflecting to the aesthetics of the skull as well. "Only the human scull can give me an impression of beauty. In spite of all genetical colseness, a skull of a chimpanzee cannot impress me aesthetically"--author confesses. In the second part of the treatise those authors are listed, who contributed to the perfection of our knowledge regarding the skull. First of all the great founder of modern anatomy, Andreas Vesalius, then Pierre Paul Broca, Jacob Benignus Winslow are mentioned here. The most important Hungarian contributors were as follow: Sámuel Rácz, Pál Bugát or--the former assistant of Broca--Aurél Török. A widely used tool for measurement of the size of the skull, the craniometer was invented by the latter. The members of the family Lenhossék have had also important results in this field of research, while descriptive anatomy of the skull was completed by microsopical anatomy thanks the activity of Géza Mihálkovits. PMID:21661257

  3. Executions and scientific anatomy.

    PubMed

    Dolezal, Antonín; Jelen, Karel; Stajnrtova, Olga

    2015-12-01

    The very word "anatomy" tells us about this branch's connection with dissection. Studies of anatomy have taken place for approximately 2.300 years already. Anatomy's birthplace lies in Greece and Egypt. Knowledge in this specific field of science was necessary during surgical procedures in ophthalmology and obstetrics. Embalming took place without public disapproval just like autopsies and manipulation with relics. Thus, anatomical dissection became part of later forensic sciences. Anatomical studies on humans themselves, which needed to be compared with the knowledge gained through studying procedures performed on animals, elicited public disapprobation and prohibition. When faced with a shortage of cadavers, anatomists resorted to obtaining bodies of the executed and suicide victims - since torture, public display of the mutilated body, (including anatomical autopsy), were perceived as an intensification of the death penalty. Decapitation and hanging were the main execution methods meted out for death sentences. Anatomists preferred intact bodies for dissection; hence, convicts could thus avoid torture. This paper lists examples of how this process was resolved. It concerns the manners of killing, vivisection on people in the antiquity and middle-ages, experiments before the execution and after, vivifying from seeming death, experiments with galvanizing electricity on fresh cadavers, evaluating of sensibility after guillotine execution, and making perfect anatomical preparations and publications during Nazism from fresh bodies of the executed. PMID:26859596

  4. NCI Updates Tobacco Policies Following Re-accreditation | Poster

    Cancer.gov

    This year, NCI was re-accredited as one of nearly 200 CEO Cancer Gold Standard employers across the United States. According to its†website, ďthe CEO Cancer Gold Standard provides a framework for employers to have a healthier workplace by focusing on cancer risk reduction, early detection, and access to clinical trials and high-quality care.Ē† As part of this re-accreditation, NCI has updated its Tobacco-Free Policy. Part of this policy includes posting signs around campus reminding visitors and staff that NCIís campus is tobacco-free. Therefore, the use of all tobacco products is prohibited. This includes cigarettes, cigars, pipes, e-cigarettes, and smokeless tobacco.

  5. Auditing the NCI Thesaurus with Semantic Web Technologies

    PubMed Central

    Mougin, Fleur; Bodenreider, Olivier

    2008-01-01

    Auditing biomedical terminologies often results in the identification of inconsistencies and thus helps to improve their quality. In this paper, we present a method based on Semantic Web technologies for auditing biomedical terminologies and apply it to the NCI thesaurus. We stored the NCI thesaurus concepts and their properties in an RDF triple store. By querying this store, we assessed the consistency of both hierarchical and associative relations from the NCI thesaurus among themselves and with corresponding relations in the UMLS Semantic Network. We show that the consistency is better for associative relations than for hierarchical relations. Causes for inconsistency and benefits from using Semantic Web technologies for auditing purposes are discussed. PMID:18999265

  6. SOP: Thawing, Propagation and Cryopreservation of NCI-PBCF-CRL2336 (HCC1937)

    Cancer.gov

    Table of Contents 1. BACKGROUND INFORMATION ON NCI-PBCF-CRL2336 (HCC1937) CELL LINE .........................3 2. GENERAL INFORMATION FOR THE THAWING, PROPAGATING AND CRYOPRESERVING OF NCI-PBCF-CRL2336 (HCC1937) ..................................................................................................................3 3. REAGENTS ...........................................................................................................................................5 A.

  7. SOP: Thawing, Propagation and Cryopreservation of NCI-PBCF-HTB75 (Caov-3)

    Cancer.gov

    Table of Contents 1. BACKGROUND INFORMATION ON NCI-PBCF-HTB75 (CAOV-3) CELL LINE................................3 2. GENERAL INFORMATION FOR THE THAWING, PROPAGATING AND CRYOPRESERVING OF NCI-PBCF- HTB75 (CAOV-3) .......................................................................................................................3 3. REAGENTS ...........................................................................................................................................5 A.

  8. 78 FR 44136 - Submission for OMB review; 30-day Comment Request: National Cancer Institute (NCI) Cancer...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-23

    ... Cancer Institute (NCI) Cancer Nanotechnology Platform Partnership Scientific Progress Reports SUMMARY..., Center for Strategic Scientific Initiatives, Office of Cancer Nanotechnology Research, National Cancer... (NCI) Alliance for Nanotechnology in Cancer Platform Partnership Scientific Progress Reports,...

  9. Comparison of a gross anatomy laboratory to online anatomy software for teaching anatomy.

    PubMed

    Mathiowetz, Virgil; Yu, Chih-Huang; Quake-Rapp, Cindee

    2016-01-01

    This study was designed to assess the grades, self-perceived learning, and satisfaction between occupational therapy students who used a gross anatomy laboratory versus online anatomy software (AnatomyTV) as tools to learn anatomy at a large public university and a satellite campus in the mid-western United States. The goal was to determine if equivalent learning outcomes could be achieved regardless of learning tool used. In addition, it was important to determine why students chose the gross anatomy laboratory over online AnatomyTV. A two group, post-test only design was used with data gathered at the end of the course. Primary outcomes were students' grades, self-perceived learning, and satisfaction. In addition, a survey was used to collect descriptive data. One cadaver prosection was available for every four students in the gross anatomy laboratory. AnatomyTV was available online through the university library. At the conclusion of the course, the gross anatomy laboratory group had significantly higher grade percentage, self-perceived learning, and satisfaction than the AnatomyTV group. However, the practical significance of the difference is debatable. The significantly greater time spent in gross anatomy laboratory during the laboratory portion of the course may have affected the study outcomes. In addition, some students may find the difference in (B+) versus (A-) grade as not practically significant. Further research needs to be conducted to identify what specific anatomy teaching resources are most effective beyond prosection for students without access to a gross anatomy laboratory. Anat Sci Educ. © 2015 American Association of Anatomists. PMID:25903289

  10. NCI at Frederick Receives a Royal Visit | Poster

    Cancer.gov

    The Center for Cancer Research (CCR) and NCI at Frederick recently had the honor of hosting Professor Dr. Her Royal Highness Princess Chulabhorn Mahidol of Thailand.  Her Royal Highness has a special interest in scientific research related to the use of natural products for treating disease. The purpose of her visit was to discuss the work on natural products being undertaken at NCI at Frederick. Her Royal Highness attended talks by researchers from both the Molecular Targets Laboratory (MTL), CCR, and the Natural Products Branch (NPB), Developmental Therapeutics Program (DTP), Division of Cancer Treatment and Diagnosis (DCTD).

  11. CRN Projects

    Cancer.gov

    The MCHCR (Dr. Vic Strecher, PI) is one of four NCI-designated Centers of Excellence in Cancer Communications Research. It was funded through a P50 grant and entails collaborating with the CRN to develop and test an efficient, theory-driven model for generating tailored health behavior interventions. The Center supports three core research projects along with several developmental studies.

  12. Anatomy relevant to conservative mastectomy

    PubMed Central

    OíConnell, Rachel L.

    2015-01-01

    Knowledge of the anatomy of the nipple and breast skin is fundamental to any surgeon practicing conservative mastectomies. In this paper, the relevant clinical anatomy will be described, mainly focusing on the anatomy of the ďoncoplastic planeĒ, the ducts and the vasculature. We will also cover more briefly the nerve supply and the arrangement of smooth muscle of the nipple. Finally the lymphatic drainage of the nipple and areola will be described. An appreciation of the relevant anatomy, together with meticulous surgical technique may minimise local recurrence and ischaemic complications. PMID:26645002

  13. Anatomy relevant to conservative mastectomy.

    PubMed

    O'Connell, Rachel L; Rusby, Jennifer E

    2015-12-01

    Knowledge of the anatomy of the nipple and breast skin is fundamental to any surgeon practicing conservative mastectomies. In this paper, the relevant clinical anatomy will be described, mainly focusing on the anatomy of the "oncoplastic plane", the ducts and the vasculature. We will also cover more briefly the nerve supply and the arrangement of smooth muscle of the nipple. Finally the lymphatic drainage of the nipple and areola will be described. An appreciation of the relevant anatomy, together with meticulous surgical technique may minimise local recurrence and ischaemic complications. PMID:26645002

  14. SOP: Thawing, Propagation and Cryopreservation of NCI-PBCF-CRL2505 (22Rv1)

    Cancer.gov

    Table of Contents 1. BACKGROUND INFORMATION ON NCI-PBCF- CRL2505 (22RV1) CELL LINE .............................3 2. GENERAL INFORMATION FOR THE THAWING, PROPAGATING AND CRYOPRESERVING OF NCI-PBCF- NCI-PBCF- CRL2505 (22RV1) ..................................................................................................3 3. REAGENTS ...........................................................................................................................................5 A.

  15. Who is repeating anatomy? Trends in an undergraduate anatomy course.

    PubMed

    Schutte, Audra F

    2016-03-01

    Anatomy courses frequently serve as prerequisites or requirements for health sciences programs. Due to the challenging nature of anatomy, each semester there are students remediating the course (enrolled in the course for a second time), attempting to earn a grade competitive for admissions into a program of study. In this retrospective study, remediation rates and trends in an undergraduate anatomy course with over 400 students enrolled each semester at a large Midwestern university were identified. Demographic data was collected from spring 2004 to spring 2010, including students' age, ethnicity, major of study, class standing, college admission tests (ACT and SAT¬ģ) scores, anatomy laboratory and lecture examination scores, and final anatomy grades for each semester. Eleven percent of the students repeated the course at least once. Gender, ethnicity, major of study and SAT scores were all shown to be associated with whether or not a student would need to repeat the course. On average, students who repeated anatomy demonstrated significant improvements in lecture and laboratory scores when comparing first and second enrollments in anatomy, and therefore also saw improved final course grades in their second enrollment. These findings will aid future instructors to identify and assist at-risk students to succeed in anatomy. Instructors from other institutions may also find the results to be useful for identifying students at risk for struggling. Anat Sci Educ 9: 171-178. ¬© 2015 American Association of Anatomists. PMID:26179910

  16. Who Is Repeating Anatomy? Trends in an Undergraduate Anatomy Course

    ERIC Educational Resources Information Center

    Schutte, Audra F.

    2016-01-01

    Anatomy courses frequently serve as prerequisites or requirements for health sciences programs. Due to the challenging nature of anatomy, each semester there are students remediating the course (enrolled in the course for a second time), attempting to earn a grade competitive for admissions into a program of study. In this retrospective study,…

  17. The anatomy of anatomy: a review for its modernization.

    PubMed

    Sugand, Kapil; Abrahams, Peter; Khurana, Ashish

    2010-01-01

    Anatomy has historically been a cornerstone in medical education regardless of nation or specialty. Until recently, dissection and didactic lectures were its sole pedagogy. Teaching methodology has been revolutionized with more reliance on models, imaging, simulation, and the Internet to further consolidate and enhance the learning experience. Moreover, modern medical curricula are giving less importance to anatomy education and to the acknowledged value of dissection. Universities have even abandoned dissection completely in favor of user-friendly multimedia, alternative teaching approaches, and newly defined priorities in clinical practice. Anatomy curriculum is undergoing international reformation but the current framework lacks uniformity among institutions. Optimal learning content can be categorized into the following modalities: (1) dissection/prosection, (2) interactive multimedia, (3) procedural anatomy, (4) surface and clinical anatomy, and (5) imaging. The importance of multimodal teaching, with examples suggested in this article, has been widely recognized and assessed. Nevertheless, there are still ongoing limitations in anatomy teaching. Substantial problems consist of diminished allotted dissection time and the number of qualified anatomy instructors, which will eventually deteriorate the quality of education. Alternative resources and strategies are discussed in an attempt to tackle these genuine concerns. The challenges are to reinstate more effective teaching and learning tools while maintaining the beneficial values of orthodox dissection. The UK has a reputable medical education but its quality could be improved by observing international frameworks. The heavy penalty of not concentrating on sufficient anatomy education will inevitably lead to incompetent anatomists and healthcare professionals, leaving patients to face dire repercussions. PMID:20205265

  18. Anatomy Adventure: A Board Game for Enhancing Understanding of Anatomy

    ERIC Educational Resources Information Center

    Anyanwu, Emeka G.

    2014-01-01

    Certain negative factors such as fear, loss of concentration and interest in the course, lack of confidence, and undue stress have been associated with the study of anatomy. These are factors most often provoked by the unusually large curriculum, nature of the course, and the psychosocial impact of dissection. As a palliative measure, AnatomyÖ

  19. Is the NCI MATCH trial a match for gynecologic oncology?

    PubMed

    Moore, Kathleen N; Mannel, Robert S

    2016-01-01

    The Precision Medicine Initiative is an NCI driven program in cancer to generate the scientific evidence needed to move the concept of precision medicine into clinical practice. The rapid development and widespread availability of next generation sequencing and other molecular interrogation of tumors has heralded a new era of knowledge about each individual's tumor at a point in time. In some instances, this information has led to new therapeutic discoveries, in most instances, this information has been uninformative or of unclear significance. The NCI Molecular Analysis for Therapy Choice (MATCH) trial [NCT02465060] which screens for molecular features that may predict response to a drug with a given mechanism of action, is a multi-study, collaborative effort between the NCI and many pharmaceutical companies to begin to clarify the significance of molecular alterations in tumors not previously studied. This trial design is in response to the recent appreciation that certain driver mutations which may be common in a particular tumor type are mutated in other diseases at low frequency (<10%). In low frequency mutations, testing the utility of certain targeted therapy requires screening large numbers of patients. This review article will discuss the types of novel trial designs that led to the development and launch of the NCI MATCH. PMID:26586415

  20. Coding Manual for the 2007 NCI Diet History Questionnaire

    Cancer.gov

    Coding Manual for the 2007 NCI Diet History Questionnaire DHQ1.2007.OSC, DHQ1.2007.Teleform, DHQ1.2007.Keypunch The 2007 version of the DHQ is distributed on the DHQ Web site (www.riskfactor.cancer.gov/DHQ) in multiple formats: 1) a format compatible

  1. 2013 NCI Alliance for Nanotechnology in Cancer Annual Bulletin

    Cancer.gov

    The NCI Alliance for Nanotechnology in Cancer Bulletin is a resource that serves to connect Alliance participants, partners, and affiliates by highlighting the innovative work of the Alliance members in their efforts to harness the power of nanotechnology to radically change the way we diagnose, treat, and prevent cancer.

  2. NCI Alliance for Nanotechnology in Cancer - Training Funding

    Cancer.gov

    The NCI Alliance for Nanotechnology in Cancer awards training grants to facilitate the training and education of the next generation of nanotechnology researchers. The grants also provide an opportunity for experienced researchers and established institutions to work together in sharing their knowledge to positively influence the future of nanotechnology.

  3. Harold Varmus Sworn in as NCI's 14th Director

    Cancer.gov

    Harold E. Varmus, M.D., today took the oath of office to become NCIís 14th director. ďItís very exciting to have you back,Ē said Health and Human Services Secretary Kathleen Sebelius during the swearing-in ceremony. ďToday is the opening of a new chapter

  4. NCI Releases Budget Proposal for Fiscal Year 2017

    Cancer.gov

    Yesterday, I was proud to submit the NCI Annual Plan and Budget Proposal for Fiscal Year 2017 to President Barack Obama. I believe that the ďBypass Budget,Ē as it has come to be known, is particularly important to cancer research this year for two reasons.

  5. Creating Start-up Companies around NCI Inventions | Poster

    Cancer.gov

    By Karen Surabian, Thomas Stackhouse, and Rose Freel, Contributing Writers, and Rosemarie Truman, Guest Writer The National Cancer Institute (NCI), led by the Technology Transfer Center (TTC),¬† the Avon Foundation, and The Center for Advancing Innovation have partnered to create a ‚Äúfirst-of-a-kind‚ÄĚ Breast Cancer Start-up Challenge.

  6. NCI-Frederick PHL Hematology / Blood Chemistry Request

    Cancer.gov

    NCI-Frederick PHL Hematology / Blood Chemistry Request: Step 1 of 4 Please complete the form below as completely as possible. Required fields are marked with an "*". ACUC Protocol Number* First Name* Last Name* Date* Sp./Strain/Code* Gender* Male Female Both Grp/Geno Building Room Phone Date

  7. NCI intramural research highlighted at 2014 AACR meeting

    Cancer.gov

    This year’s American Association for Cancer Research meeting featured plenary talks by two NCI scientists, Steven Rosenberg, M.D., and Louis Staudt, M.D., Ph.D., that highlighted the challenges in developing varied and potentially synergistic treatments f

  8.              NCI Ethics

    Cancer.gov

    Welcome to the first edition of the NCI Office of Ethics Newsletter!  We created this newsletter to keep staff up to date on ethics topics, news, and current events.  Please feel free to contact us with questions, requests for newsletter article topics or

  9. NCI Program For Validating Tests in Cancer Clinical Trials

    Cancer.gov

    In order to conduct rigorous and robust clinical trials, the tests, or assays, used in those trials must meet optimum standards. To bring those assays and standards in line with 21st century technology, NCI's Division of Cancer Treatment and Diagnosis has

  10. Centros oncológicos designados por el NCI

    Cancer.gov

    El programa de centros oncológicos designados por el Instituto Nacional del Cáncer (NCI) reconoce a los centros de todo el país que cumplen con rigurosos criterios para participar en proyectos avanzados de primer nivel para la investigación multidisciplinaria del cáncer.

  11. NCI Community Oncology Research Program (NCORP) | Division of Cancer Prevention

    Cancer.gov

    The NCI Community Oncology Research Program (NCORP) is a national network of cancer care investigators, providers, academia, and other organizations that care for diverse populations in health systems. View the list of publications from NCORP. | Clinical Trials network of cancer care professionals who care for diverse populations across the U.S.

  12. NCI scientists image proteins displayed on HIV surface

    Cancer.gov

    Using a technique called cryo-electron microscopy, researchers NCI have been able to detect shape changes in a protein called Env that is part of HIV (the human immunodeficiency virus). HIV infection is initiated when Env binds to receptors on host cells.

  13.              NCI Ethics

    Cancer.gov

       Thanks for visiting the NCI Ethics Newsletter webpage!  Click on the links below to access the most current version of the newsletter, as well as the archives.   Volume 1, January 2012  Volume 2, May 2012  Volume 3, September 2012

  14.              NCI Ethics

    Cancer.gov

      May 2012 NCI ETHICS OFFICE UPDATES Widely Attended Gathering Form Now Available in NEES The NIH-2803 Request for Approval to Accept Free Attendance under the Widely Attended Gathering (WAG) exception is now ready for use by employees in the NIH Enterpri

  15. NCI: Cancer Mortality Maps and Graphs: Contact Us

    Cancer.gov

    Contact us For technical or navigational difficulties: send a message to the Cancer Atlas administrator (atlasadm@pop.nci.nih.gov). To comment on this Web site: your feedback is greatly appreciated and will help to make this a better resource. Please

  16. Health Instruction Packages: Cardiac Anatomy.

    ERIC Educational Resources Information Center

    Phillips, Gwen; And Others

    Text, illustrations, and exercises are utilized in these five learning modules to instruct nurses, students, and other health care professionals in cardiac anatomy and functions and in fundamental electrocardiographic techniques. The first module, "Cardiac Anatomy and Physiology: A Review" by Gwen Phillips, teaches the learner to draw and labelÖ

  17. Virtual anatomy: an anatomist's playground.

    PubMed

    Spitzer, Victor M; Scherzinger, Ann L

    2006-04-01

    Virtual anatomy presents significant advantages over the reality of a cadaver as it can provide different views and perspectives, portability, longevity, standardization, diversity and most importantly the opportunity to learn the anatomy of the living human body instead of the corpse. Virtual anatomy is the life-like appearance of visible anatomy, a good example of which is the evolution of the Visible Human. Racial and statistical diversity is already developing as the population of photographic "Visible Humans" is now at least 10. Virtual anatomy should include additional diversity and therefore, consideration should be given to the preparation of more visible anatomy that will better support the virtual integration of all areas of physiology, kinematics, pathology and pathophysiology, development and evolution. Integration of anatomists with mathematicians, computer scientists, information scientists, physiologists, pathologists and clinicians (and LIST other basic scientist) is needed in order to facilitate this development. As this unfolds it is proposed, or challenged, that anatomists should maintain their position of responsibility for building anatomy as the foundation for all medical and healthcare education. In order to maintain that position they must understand and participate in this development and enjoy the rewards of teaching more visually empowering, functional, and clinical anatomy. The trip is a long one and is only about to begin but the train is leaving. Are you on board? PMID:16565945

  18. Curriculum Guidelines for Gross Anatomy.

    ERIC Educational Resources Information Center

    Journal of Dental Education, 1993

    1993-01-01

    The American Association of Dental Schools' revised guidelines on curricula for gross anatomy suggest percentages of effort and time devoted to curricular areas, offer a rationale for anatomy instruction, note primary educational goals and prerequisites, outline content, and make recommendations for sequencing. Appropriate faculty and facilities…

  19. How Much Anatomy Is Enough?

    ERIC Educational Resources Information Center

    Bergman, Esther M.; Prince, Katinka J. A. H.; Drukker, Jan; van der Vleuten, Cees P. M.; Scherpbier, Albert J. J. A.

    2008-01-01

    Innovations in undergraduate medical education, such as integration of disciplines and problem based learning, have given rise to concerns about students' knowledge of anatomy. This article originated from several studies investigating the knowledge of anatomy of students at the eight Dutch medical schools. The studies showed that undergraduateÖ

  20. Health Instruction Packages: Cardiac Anatomy.

    ERIC Educational Resources Information Center

    Phillips, Gwen; And Others

    Text, illustrations, and exercises are utilized in these five learning modules to instruct nurses, students, and other health care professionals in cardiac anatomy and functions and in fundamental electrocardiographic techniques. The first module, "Cardiac Anatomy and Physiology: A Review" by Gwen Phillips, teaches the learner to draw and label…

  1. Provocative Questions in Cancer: NCI Seminar

    Cancer.gov

    science writers' seminar to discuss various aspects of one of NCI’s signature efforts -- the Provocative Questions project. Discussion will focus on the scientific research that surrounds some of these questions.

  2. Carpal Ligament Anatomy and Biomechanics.

    PubMed

    Pulos, Nicholas; Bozentka, David J

    2015-08-01

    A fundamental understanding of the ligamentous anatomy of the wrist is critical for any physician attempting to treat carpal instability. The anatomy of the wrist is complex, not only because of the number of named structures and their geometry but also because of the inconsistencies in describing these ligaments. The complex anatomy of the wrist is described through a review of the carpal ligaments and their effect on normal carpal motion. Mastery of this topic facilitates the physician's understanding of the patterns of instability that are seen clinically. PMID:26205699

  3. The painted Amsterdam anatomy lessons: anatomy performances in dissecting rooms?

    PubMed

    Baljet, B

    2000-01-01

    The Anatomy Lesson of Dr. Nicolaes Tulp, painted by Rembrandt in 1632, has recently been fully restored. From 02-10-98 to 10-01-99 this painting and some other Amsterdam painted anatomy lessons were exhibited in the Mauritshuis in The Hague, with the title "Rembrandt under the scalpel". The unique Tulp painting is one of those portraits painted in the tradition of the famous group portraits which flourished in 17th-century Holland, a predominantly urban, middle-class society where the main patrons of the arts were the leading citizens of the various towns. Moreover, it is a portrait in the tradition of the anatomy lessons especially painted for the Guild of Surgeons for their Guild Room. Nine such lessons have been painted for the guild and are still to be found in Dutch museums (Mauritshuis and Amsterdam Historical Museum). The anatomy lesson of Prof. Andreas Bonn, dated 1792, as well as some group portraits of the leading persons of the guild also play an important role in the Amsterdam group portraits. In 1925 the Amsterdam anatomist Louis Bolk commissioned Martin Monnickendam to paint another anatomy lesson. The restoration of the painting of Dr. Tulp has provided new information concerning the original composition of Rembrandt and the later additions. However, from an anatomical point of view, it is doubtful whether the Amsterdam anatomy lessons depict a real contemporary anatomical demonstration. They provide, together with archival sources, reliable information about the praelectores anatomiae and the leading persons of the guild, but fail to give much information about the dissecting room, the anatomy theatre or the procedure. The anatomical demonstration procedures of the guild are discussed in relation to the painted anatomy lessons. PMID:10668553

  4. NCI Updates Tobacco Policies Following Re-accreditation | Poster

    Cancer.gov

    This year, NCI was re-accredited as one of nearly 200 CEO Cancer Gold Standard employers across the United States. According to its¬†website, ‚Äúthe CEO Cancer Gold Standard provides a framework for employers to have a healthier workplace by focusing on cancer risk reduction, early detection, and access to clinical trials and high-quality care.‚Ä̬† As part of this re-accreditation, NCI has updated its Tobacco-Free Policy. Part of this policy includes posting signs around campus reminding visitors and staff that NCI‚Äôs campus is tobacco-free. Therefore, the use of all tobacco products is prohibited. This includes cigarettes, cigars, pipes, e-cigarettes, and smokeless tobacco.

  5. Industry Collaboration ó NCI - Cooperative Group - Industry Relationship Guidelines

    Cancer.gov

    Each CTA or CRADA defines certain obligations for the government and the Collaborator. Generally, these obligations focus on intellectual property and data rights, which may arise pursuant to these studies. Under federal funding agreement guidelines and the agreements in place between the Cooperative Groups and the NCI, certain obligations and guidelines apply to the Cooperative Groups. Compliance with any of the guidelines (in particular, publication review, data access, and intellectual property licensing) is mandatory for the Cooperative Group.

  6. Susan Koogle Marks 40+ Years at NCI at Frederick | Poster

    Cancer.gov

    By Nancy Parrish, Staff Writer In 1973, Susan Koogle commuted from Washington County to a small data processing company in Arlington, Va. When gas prices spiked from 25 to 54 cents a gallon, she began to look for a job closer to home. That’s when she came to work at NCI at Frederick, and in December 2013, she marked her 40th year with the facility.

  7. NCI Alliance for Nanotechnology in Cancer - Tutorials and Seminar Series

    Cancer.gov

    View details about tutorials and seminars hosted by Alliance members and members of the cancer research community. These events provide a forum for sharing innovative perspectives on research and development efforts in the field of nanotechnology and their application to cancer diagnosis, treatment, and prevention. Also visit the Event Listing section to find scientific meetings and events where NCI Alliance for Nanotechnology in Cancer leaders and members are participating.

  8. NCI Community Cancer Centers Program - Related Programs - Cancer Information Service

    Cancer.gov

    The National Cancer InstituteÔŅĹs (NCI) Cancer Information Service (CIS) educates the public about cancer prevention, risk factors, symptoms, diagnosis, treatment, and research . CIS information specialists provide the latest, most accurate information about cancer by telephone, TTY, instant messaging, and e-mail and operates the NCIÔŅĹs Smoking Quitline. Through its Partnership Program, the CIS works with established national, regional, and state organizations to reach those most in need of cancer information.

  9. NCI CAM News Fall 2007, Vol 2, Issue 2

    Cancer.gov

    Vol.2 - Issue 1 On November 17, 2006, the Office of Cancer Complementary and Alternative Medicine (OCCAM) hosted a half-day meeting to which staff members from the National Cancer Institute (NCI), others from the National Institutes of Health (NIH), as well as academia were invited to review and discuss information about the historical and current use of mixed bacterial vaccines as cancer therapy. The primary goal of the meeting was to provide Dr.

  10. NCI-Frederick Animal Care and Use Committee

    Cancer.gov

    The NCI has two separate assurances on file with the NIH Office of Laboratory Animal Welfare for the Frederick and Bethesda campuses. As a result, there are two separate Animal Care and Use Committees designed to meet the needs of investigators at each of these locations. To ensure you are provided with the appropriate guidance, please select the ACUC where your animals will be housed.

  11. NCI investment in nanotechnology: achievements and challenges for the future.

    PubMed

    Dickherber, Anthony; Morris, Stephanie A; Grodzinski, Piotr

    2015-01-01

    Nanotechnology offers an exceptional and unique opportunity for developing a new generation of tools addressing persistent challenges to progress in cancer research and clinical care. The National Cancer Institute (NCI) recognizes this potential, which is why it invests roughly $150 M per year in nanobiotechnology training, research and development. By exploiting the various capacities of nanomaterials, the range of nanoscale vectors and probes potentially available suggests much is possible for precisely investigating, manipulating, and targeting the mechanisms of cancer across the full spectrum of research and clinical care. NCI has played a key role among federal R&D agencies in recognizing early the value of nanobiotechnology in medicine and committing to its development as well as providing training support for new investigators in the field. These investments have allowed many in the research community to pursue breakthrough capabilities that have already yielded broad benefits. Presented here is an overview of how NCI has made these investments with some consideration of how it will continue to work with this research community to pursue paradigm-changing innovations that offer relief from the burdens of cancer. PMID:25429991

  12. OLFACTION: ANATOMY, PHYSIOLOGY AND BEHAVIOR

    EPA Science Inventory

    The anatomy, physiology and function of the olfactory system are reviewed, as are the normal effects of olfactory stimulation. It is speculated that olfaction may have important but unobtrusive effects on human behavior.

  13. Curricular Guidelines in Gross Anatomy.

    ERIC Educational Resources Information Center

    Horn, Stanton D.; And Others

    1981-01-01

    An outline of AADS curricular guidelines for gross anatomy in dental education includes primary educational goals, prerequisites, core content, specific course objectives for each section of content, sequencing, faculty requirements, and facility and equipment needs. (MSE)

  14. Olfaction: anatomy, physiology and behavior

    PubMed Central

    Benignus, Vernon A.; Prah, James D.

    1982-01-01

    The anatomy, physiology and function of the olfactory system are reviewed, as are the normal effects of olfactory stimulation. It is speculated that olfaction may have important but unobtrusive effects on human behavior. PMID:7084147

  15. Collaboration Opportunities with the Cancer Human Biobank (caHUB) at NCI | NCI Technology Transfer Center | TTC

    Cancer.gov

    The Biorepositories and Biospecimen Research Branch (BBRB) at the National Cancer Institute has developed the Cancer Human Biobank (caHUB), which is a unique infrastructure for collecting biospecimens for the purpose of conducting biospecimen research. Biospecimens from the BPV program will be made available to collaborators with the capability to perform molecular analysis as part of a collaborative research agreement with the NCI-BBRB.

  16. [Dental anatomy of dogs].

    PubMed

    Sarkisian, E G

    2014-12-01

    The aim of the research was to investigate dog teeth anatomy as animal model for study of etiopathogenesis of caries disease and physiological tooth wear in human. After examining the dog's dental system, following conclusions were drawn: the dog has 42 permanent teeth, which are distributed over the dental arches not equally, and so the upper dentition consists of 20, and the lower of 22 teeth. The largest are considered upper fourth premolar and lower first molars, which are called discordant teeth. Between discordant teeth and fangs a dog has an open bite, which is limited to the top and bottom conical crown premolar teeth. Thus, in the closed position of the jaws, behind this occlusion is limited by discordant teeth, just in contact are smaller in size two molars. Only large dog's molars in a valid comparison can be likened to human molars, which allows us to use them in an analog comparison between them with further study of the morphological features ensure durability short-crown teeth and their predisposition to caries. PMID:25617107

  17. Guest Expert: MaryAnn Monroe and NCI's Cancer Information Service | accrualnet.cancer.gov

    Cancer.gov

    Please join me in welcoming our monthly guest expert, MaryAnn Monroe, Program Director of NCI's Cancer Information Service (CIS). If you are not already aware of the CIS, it is a treasure within the NCI and the cancer information specialists who respond to questions from patients and the public are amazing. I had the opportunity to work with the NCI's CIS for several years and I have so much respect and appreciation for the wonderful service they provide.

  18. NCI Scientists Awarded National Medal of Technology and Innovation by President Obama | Poster

    Cancer.gov

    Two NCI scientists received the National Medal of Technology and Innovation, the nation’s highest honor for technological achievement. The award was announced by President Obama in October. The honorees, John Schiller, Ph.D., Laboratory of Cellular Oncology (LCO), Center for Cancer Research, NCI, and Douglas Lowy, M.D., also from LCO and NCI deputy director, received their medals at a White House ceremony on Nov. 20.

  19. NCI Community Cancer Centers Program - Pilot Subcommittees - NCCCP Program Advisory Committee

    Cancer.gov

    NCI Community Cancer Centers Program - Pilot Subcommittees - NCCCP Program Advisory Committee Search NCCCP Pilot Goals Overview Pilot Subcommittees Pilot Executive Subcommittee Disparities Clinical Trials Information

  20. The assessment of virtual reality for human anatomy instruction

    NASA Technical Reports Server (NTRS)

    Benn, Karen P.

    1994-01-01

    This research project seeks to meet the objective of science training by developing, assessing, and validating virtual reality as a human anatomy training medium. In ideal situations, anatomic models, computer-based instruction, and cadaver dissection are utilized to augment the traditional methods of instruction. At many institutions, lack of financial resources limits anatomy instruction to textbooks and lectures. However, human anatomy is three dimensional, unlike the one dimensional depiction found in textbooks and the two dimensional depiction found on the computer. Virtual reality is a breakthrough technology that allows one to step through the computer screen into a three dimensional world. This technology offers many opportunities to enhance science education. Therefore, a virtual testing environment of the abdominopelvic region of a human cadaver was created to study the placement of body parts within the nine anatomical divisions of the abdominopelvic region and the four abdominal quadrants.

  1. The place of surface anatomy in the medical literature and undergraduate anatomy textbooks.

    PubMed

    Azer, Samy A

    2013-01-01

    The aims of this review were to examine the place of surface anatomy in the medical literature, particularly the methods and approaches used in teaching surface and living anatomy and assess commonly used anatomy textbooks in regard to their surface anatomy contents. PubMed and MEDLINE databases were searched using the following keywords "surface anatomy," "living anatomy," "teaching surface anatomy," "bony landmarks," "peer examination" and "dermatomes". The percentage of pages covering surface anatomy in each textbook was calculated as well as the number of images covering surface anatomy. Clarity, quality and adequacy of surface anatomy contents was also examined. The search identified 22 research papers addressing methods used in teaching surface anatomy, 31 papers that can help in the improvement of surface anatomy curriculum, and 12 anatomy textbooks. These teaching methods included: body painting, peer volunteer surface anatomy, use of a living anatomy model, real time ultrasound, virtual (visible) human dissector (VHD), full body digital x-ray of cadavers (Lodox(¬ģ) Statscan(¬ģ) images) combined with palpating landmarks on peers and the cadaver, as well as the use of collaborative, contextual and self-directed learning. Nineteen of these studies were published in the period from 2006 to 2013. The 31 papers covered evidence-based and clinically-applied surface anatomy. The percentage of surface anatomy in textbooks' contents ranged from 0 to 6.2 with an average of 3.4%. The number of medical illustrations on surface anatomy varied from 0 to 135. In conclusion, although there has been a progressive increase in publications addressing methods used in teaching surface anatomy over the last six to seven years, most anatomy textbooks do not provide students with adequate information about surface anatomy. Only three textbooks provided a solid explanation and foundation of understanding surface anatomy. PMID:23650274

  2. Student perceptions about learning anatomy

    NASA Astrophysics Data System (ADS)

    Notebaert, Andrew John

    This research study was conducted to examine student perceptions about learning anatomy and to explore how these perceptions shape the learning experience. This study utilized a mixed-methods design in order to better understand how students approach learning anatomy. Two sets of data were collected at two time periods; one at the beginning and one at the end of the academic semester. Data consisted of results from a survey instrument that contained open-ended questions and a questionnaire and individual student interviews. The questionnaire scored students on a surface approach to learning (relying on rote memorization and knowing factual information) scale and a deep approach to learning (understanding concepts and deeper meaning behind the material) scale. Students were asked to volunteer from four different anatomy classes; two entry-level undergraduate courses from two different departments, an upper-level undergraduate course, and a graduate level course. Results indicate that students perceive that they will learn anatomy through memorization regardless of the level of class being taken. This is generally supported by the learning environment and thus students leave the classroom believing that anatomy is about memorizing structures and remembering anatomical terminology. When comparing this class experience to other academic classes, many students believed that anatomy was more reliant on memorization techniques for learning although many indicated that memorization is their primary learning method for most courses. Results from the questionnaire indicate that most students had decreases in both their deep approach and surface approach scores with the exception of students that had no previous anatomy experience. These students had an average increase in surface approach and so relied more on memorization and repetition for learning. The implication of these results is that the learning environment may actually amplify students' perceptions of the anatomy course at all levels and experiences of enrolled students. Instructors wanting to foster deeper approaches to learning may need to apply instructional techniques that both support deeper approaches to learning and strive to change students' perceptions away from believing that anatomy is strictly memorization and thus utilizing surface approaches to learning.

  3. NCI at Frederick Employees Sew for Cancer | Poster

    Cancer.gov

    By Carolynne Keenan, Contributing Writer The R&W Club Frederick hosted a sewing party on Feb. 18 to give employees a chance to help sew pillowcases for children hospitalized for illnesses and cancer treatments. The nonprofit organization ConKerr Cancer provides the pillowcases to children across the country. Melissa Porter, administrative manager, Office of Scientific Operations, NCI at Frederick, and vice chair of the R&W Club Frederick, said the event went well. While the turnout was lower than expected, 27 pillowcases were completed, she said.

  4. Before You Collaborate, You Should Partner with NCI TTC | Poster

    Cancer.gov

    By Karen Surabian, Thomas Stackhouse, and Jeffrey W. Thomas, Contributing Writers As the fall and winter seasons progress, you may be attending more scientific conferences, where you may find a number of opportunities for research collaborations. To assist your lab in reaching its research goals through collaborations, the staff of the National Cancer Institute Technology Transfer Center (NCI TTC) can guide you through a tool box of agreements you may need for protecting your intellectual property (IP) and effectively managing your collaboration. 

  5. Integrating constitutive gene expression and chemoactivity: mining the NCI60 anticancer screen.

    PubMed

    Covell, David G

    2012-01-01

    Studies into the genetic origins of tumor cell chemoactivity pose significant challenges to bioinformatic mining efforts. Connections between measures of gene expression and chemoactivity have the potential to identify clinical biomarkers of compound response, cellular pathways important to efficacy and potential toxicities; all vital to anticancer drug development. An investigation has been conducted that jointly explores tumor-cell constitutive NCI60 gene expression profiles and small-molecule NCI60 growth inhibition chemoactivity profiles, viewed from novel applications of self-organizing maps (SOMs) and pathway-centric analyses of gene expressions, to identify subsets of over- and under-expressed pathway genes that discriminate chemo-sensitive and chemo-insensitive tumor cell types. Linear Discriminant Analysis (LDA) is used to quantify the accuracy of discriminating genes to predict tumor cell chemoactivity. LDA results find 15% higher prediction accuracies, using ‚ąľ30% fewer genes, for pathway-derived discriminating genes when compared to genes derived using conventional gene expression-chemoactivity correlations. The proposed pathway-centric data mining procedure was used to derive discriminating genes for ten well-known compounds. Discriminating genes were further evaluated using gene set enrichment analysis (GSEA) to reveal a cellular genetic landscape, comprised of small numbers of key over and under expressed on- and off-target pathway genes, as important for a compound's tumor cell chemoactivity. Literature-based validations are provided as support for chemo-important pathways derived from this procedure. Qualitatively similar results are found when using gene expression measurements derived from different microarray platforms. The data used in this analysis is available at http://pubchem.ncbi.nlm.nih.gov/andhttp://www.ncbi.nlm.nih.gov/projects/geo (GPL96, GSE32474). PMID:23056181

  6. The Anatomy of Anatomy: A Review for Its Modernization

    ERIC Educational Resources Information Center

    Sugand, Kapil; Abrahams, Peter; Khurana, Ashish

    2010-01-01

    Anatomy has historically been a cornerstone in medical education regardless of nation or specialty. Until recently, dissection and didactic lectures were its sole pedagogy. Teaching methodology has been revolutionized with more reliance on models, imaging, simulation, and the Internet to further consolidate and enhance the learning experience.…

  7. Anatomy Adventure: A Board Game for Enhancing Understanding of Anatomy

    ERIC Educational Resources Information Center

    Anyanwu, Emeka G.

    2014-01-01

    Certain negative factors such as fear, loss of concentration and interest in the course, lack of confidence, and undue stress have been associated with the study of anatomy. These are factors most often provoked by the unusually large curriculum, nature of the course, and the psychosocial impact of dissection. As a palliative measure, Anatomy…

  8. The Anatomy of Anatomy: A Review for Its Modernization

    ERIC Educational Resources Information Center

    Sugand, Kapil; Abrahams, Peter; Khurana, Ashish

    2010-01-01

    Anatomy has historically been a cornerstone in medical education regardless of nation or specialty. Until recently, dissection and didactic lectures were its sole pedagogy. Teaching methodology has been revolutionized with more reliance on models, imaging, simulation, and the Internet to further consolidate and enhance the learning experience.Ö

  9. About CBIIT ó CBIIT: Welcome to the NCI Center for Biomedical Informatics and Information Technology

    Cancer.gov

    NCI created CBIIT to lead the coordination, development, and deployment of enterprise-wide digital capabilities (including biomedical informatics, scientific-management information systems, and computing resources) in support of the Institute's initiatives. Through CBIIT, NCI is helping to speed scientific discovery and facilitate translational research by using IT and informatics to address complex research challenges.

  10. 78 FR 2678 - Proposed Collection; Comment Request (60-Day FRN): The National Cancer Institute (NCI...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-14

    ... National Cancer Institute (NCI) SmokefreeTXT (Text Message) Program Evaluation (NCI) SUMMARY: In compliance... memorandum. This study seeks to assess the efficacy of the SmokefreeTXT program, a text message smoking... text- messaging service and a series of web-based surveys. All web-based survey data will be...

  11. A Manual for Authoring and Submitting Protocols Sponsored by DCTD, NCI

    Cancer.gov

    The Protocol and Information Office (PIOPIO) is the administrative arm of the Division of Cancer Treatment and DiagnosisDivision of Cancer Treatment and DiagnosisDCTD (DCTD), National Cancer InstituteNational Cancer InstituteNCI (NCI) and serves to support DCTD in the development of new anti-cancer therapies through the use of cancer clinical trials.

  12. Terminology ó CBIIT: Welcome to the NCI Center for Biomedical Informatics and Information Technology

    Cancer.gov

    Enterprise Vocabulary Services (EVS) works with NCI and extramural partners to develop, license, and publish terminology; to support software applications; and to promote harmonization and shared standards. EVS provides the foundational layer for NCI's informatics infrastructure, and participates in federal and international standards efforts.

  13. Rep. Delaney Learns about Breast Cancer Research at NCI at Frederick | Poster

    Cancer.gov

    By Andrea Frydl, Contributing Writer Rep. John Delaney (D-Md., 6th District) visited the NCI Campus at Frederick on October 21 to learn more about the research that scientists at NCI at Frederick are doing on breast cancer. October is Breast Cancer Awareness month.

  14. Effects of Training Experienced Teachers in the Use of the One-Minute Preceptor Technique in the Gross Anatomy Laboratory

    ERIC Educational Resources Information Center

    Chan, Lap Ki; Sharma, Neel

    2014-01-01

    The one-minute preceptor (OMP) is a time-efficient, learner-centered teaching method used in a busy ambulatory care setting. This project evaluated the effects of training experienced anatomy teachers in the use of the OMP in the gross anatomy laboratory on students' perceived learning. Second-year medical students from a five-year,…

  15. The Use of Limericks to Engage Student Interest and Promote Active Learning in an Undergraduate Course in Functional Anatomy

    ERIC Educational Resources Information Center

    Carnegie, Jacqueline A.

    2012-01-01

    The study of anatomy is a content-dense discipline with a challenging vocabulary. A mnemonic is a series of letters, a word, a phrase, or a rhyme that students can use when studying to facilitate recall. This project was designed to promote active learning in undergraduate students studying anatomy and physiology by asking them to create limericksÖ

  16. Effects of Training Experienced Teachers in the Use of the One-Minute Preceptor Technique in the Gross Anatomy Laboratory

    ERIC Educational Resources Information Center

    Chan, Lap Ki; Sharma, Neel

    2014-01-01

    The one-minute preceptor (OMP) is a time-efficient, learner-centered teaching method used in a busy ambulatory care setting. This project evaluated the effects of training experienced anatomy teachers in the use of the OMP in the gross anatomy laboratory on students' perceived learning. Second-year medical students from a five-year,Ö

  17. Functional Anatomy of the Shoulder

    PubMed Central

    Terry, Glenn C.; Chopp, Thomas M.

    2000-01-01

    Objective: Movements of the human shoulder represent the result of a complex dynamic interplay of structural bony anatomy and biomechanics, static ligamentous and tendinous restraints, and dynamic muscle forces. Injury to 1 or more of these components through overuse or acute trauma disrupts this complex interrelationship and places the shoulder at increased risk. A thorough understanding of the functional anatomy of the shoulder provides the clinician with a foundation for caring for athletes with shoulder injuries. Data Sources: We searched MEDLINE for the years 1980 to 1999, using the key words ďshoulder,Ē ďanatomy,Ē ďglenohumeral joint,Ē ďacromioclavicular joint,Ē ďsternoclavicular joint,Ē ďscapulothoracic joint,Ē and ďrotator cuff.Ē Data Synthesis: We examine human shoulder movement by breaking it down into its structural static and dynamic components. Bony anatomy, including the humerus, scapula, and clavicle, is described, along with the associated articulations, providing the clinician with the structural foundation for understanding how the static ligamentous and dynamic muscle forces exert their effects. Commonly encountered athletic injuries are discussed from an anatomical standpoint. Conclusions/Recommendations: Shoulder injuries represent a significant proportion of athletic injuries seen by the medical provider. A functional understanding of the dynamic interplay of biomechanical forces around the shoulder girdle is necessary and allows for a more structured approach to the treatment of an athlete with a shoulder injury. PMID:16558636

  18. Curriculum Guidelines for Microscopic Anatomy.

    ERIC Educational Resources Information Center

    Journal of Dental Education, 1993

    1993-01-01

    The American Association of Dental Schools' guidelines for curricula in microscopic anatomy offer an overview of the histology curriculum, note primary educational goals, outline specific content for general and oral histology, suggest prerequisites, and make recommendations for sequencing. Appropriate faculty and facilities are also suggested.…

  19. Curriculum Guidelines for Microscopic Anatomy.

    ERIC Educational Resources Information Center

    Journal of Dental Education, 1993

    1993-01-01

    The American Association of Dental Schools' guidelines for curricula in microscopic anatomy offer an overview of the histology curriculum, note primary educational goals, outline specific content for general and oral histology, suggest prerequisites, and make recommendations for sequencing. Appropriate faculty and facilities are also suggested.Ö

  20. On the Anatomy of Understanding

    ERIC Educational Resources Information Center

    Wilhelmsson, Niklas; Dahlgren, Lars Owe; Hult, Hakan; Josephson, Anna

    2011-01-01

    In search for the nature of understanding of basic science in a clinical context, eight medical students were interviewed, with a focus on their view of the discipline of anatomy, in their fourth year of study. Interviews were semi-structured and took place just after the students had finished their surgery rotations. Phenomenographic analysis wasÖ

  1. Computational Environments and Analysis methods available on the NCI High Performance Computing (HPC) and High Performance Data (HPD) Platform

    NASA Astrophysics Data System (ADS)

    Evans, B. J. K.; Foster, C.; Minchin, S. A.; Pugh, T.; Lewis, A.; Wyborn, L. A.; Evans, B. J.; Uhlherr, A.

    2014-12-01

    The National Computational Infrastructure (NCI) has established a powerful in-situ computational environment to enable both high performance computing and data-intensive science across a wide spectrum of national environmental data collections - in particular climate, observational data and geoscientific assets. This paper examines 1) the computational environments that supports the modelling and data processing pipelines, 2) the analysis environments and methods to support data analysis, and 3) the progress in addressing harmonisation of the underlying data collections for future transdisciplinary research that enable accurate climate projections. NCI makes available 10+ PB major data collections from both the government and research sectors based on six themes: 1) weather, climate, and earth system science model simulations, 2) marine and earth observations, 3) geosciences, 4) terrestrial ecosystems, 5) water and hydrology, and 6) astronomy, social and biosciences. Collectively they span the lithosphere, crust, biosphere, hydrosphere, troposphere, and stratosphere. The data is largely sourced from NCI's partners (which include the custodians of many of the national scientific records), major research communities, and collaborating overseas organisations. The data is accessible within an integrated HPC-HPD environment - a 1.2 PFlop supercomputer (Raijin), a HPC class 3000 core OpenStack cloud system and several highly connected large scale and high-bandwidth Lustre filesystems. This computational environment supports a catalogue of integrated reusable software and workflows from earth system and ecosystem modelling, weather research, satellite and other observed data processing and analysis. To enable transdisciplinary research on this scale, data needs to be harmonised so that researchers can readily apply techniques and software across the corpus of data available and not be constrained to work within artificial disciplinary boundaries. Future challenges will involve the further integration and analysis of this data across the social sciences to facilitate the impacts across the societal domain, including timely analysis to more accurately predict and forecast future climate and environmental state.

  2. Anatomy of a Bird

    NASA Astrophysics Data System (ADS)

    2007-12-01

    Using ESO's Very Large Telescope, an international team of astronomers [1] has discovered a stunning rare case of a triple merger of galaxies. This system, which astronomers have dubbed 'The Bird' - albeit it also bears resemblance with a cosmic Tinker Bell - is composed of two massive spiral galaxies and a third irregular galaxy. ESO PR Photo 55a/07 ESO PR Photo 55a/07 The Tinker Bell Triplet The galaxy ESO 593-IG 008, or IRAS 19115-2124, was previously merely known as an interacting pair of galaxies at a distance of 650 million light-years. But surprises were revealed by observations made with the NACO instrument attached to ESO's VLT, which peered through the all-pervasive dust clouds, using adaptive optics to resolve the finest details [2]. Underneath the chaotic appearance of the optical Hubble images - retrieved from the Hubble Space Telescope archive - the NACO images show two unmistakable galaxies, one a barred spiral while the other is more irregular. The surprise lay in the clear identification of a third, clearly separate component, an irregular, yet fairly massive galaxy that seems to be forming stars at a frantic rate. "Examples of mergers of three galaxies of roughly similar sizes are rare," says Petri V√§is√§nen, lead author of the paper reporting the results. "Only the near-infrared VLT observations made it possible to identify the triple merger nature of the system in this case." Because of the resemblance of the system to a bird, the object was dubbed as such, with the 'head' being the third component, and the 'heart' and 'body' making the two major galaxy nuclei in-between of tidal tails, the 'wings'. The latter extend more than 100,000 light-years, or the size of our own Milky Way. ESO PR Photo 55b/07 ESO PR Photo 55b/07 Anatomy of a Bird Subsequent optical spectroscopy with the new Southern African Large Telescope, and archive mid-infrared data from the NASA Spitzer space observatory, confirmed the separate nature of the 'head', but also added further surprises. The 'head' and major parts of the 'Bird' are moving apart at more than 400 km/s (1.4 million km/h!). Observing such high velocities is very rare in merging galaxies. Also, the 'head' appears to be the major source of infrared luminosity in the system, though it is the smallest of the three galaxies. "It seems that NACO has caught the action right at the time of the first high-speed fly-by of the 'head' galaxy through the system consisting of the other two galaxies," says Seppo Mattila, member of the discovery team. "These two galaxies must have met earlier, probably a couple of hundred million years ago." The 'head' is forming stars violently, at a rate of nearly 200 solar masses per year, while the other two galaxies appear to be at a more quiescent epoch of their interaction-induced star formation history. The 'Bird' belongs to the prestigious family of luminous infrared galaxies, with an infrared luminosity nearly one thousand billion times that of the Sun. This family of galaxies has long been thought to signpost important events in galaxy evolution, such as mergers of galaxies, which in turn trigger bursts of star formation, and may eventually lead to the formation of a single elliptical galaxy. The findings presented here are reported in a paper to appear in a future issue of the journal Monthly Notices of the Royal Astronomical Society ("Adaptive optics imaging and optical spectroscopy of a multiple merger in a luminous infrared galaxy", by P. V√§is√§nen" et al.). Note [1]: The team is composed of P. V√§is√§nen, A. Kniazev, D. A. H. Buckley, L. Crause, Y. Hashimoto, N. Loaring, E. Romero-Colmenero, and M. Still (SAAO, South Africa), S. Mattila (Tuorla Observatory, Finland), A. Adamo and G. √Ėstlin (Stockholm University, Sweden), A. Efstathiou (Cyprus College, Nicosia, Cyprus), D. Farrah (Cornell University, USA), P. H. Johansson (Universit√§ts-Sternwarte M√ľnchen, Germany), E. B. Burgh and K. Nordsieck (University of Wisconsin, USA), P. Lira (Universidad de Chile, Santiago, Chile), A. Zijlstra (University of Manchester, UK ), and S. Ryder (AAO, Australia). [2]: The final resolution was better than a tenth of an arcsecond, that is, the angle sustained by a 2-cm coin seen from a distance of 40 km. This is roughly a factor 600 better than what a keen human eye can distinguish.

  3. Anatomy adventure: a board game for enhancing understanding of anatomy.

    PubMed

    Anyanwu, Emeka G

    2014-01-01

    Certain negative factors such as fear, loss of concentration and interest in the course, lack of confidence, and undue stress have been associated with the study of anatomy. These are factors most often provoked by the unusually large curriculum, nature of the course, and the psychosocial impact of dissection. As a palliative measure, Anatomy Adventure, a board game on anatomy was designed to reduce some of these pressures, emphasize student centered and collaborative learning styles, and add fun to the process of learning while promoting understanding and retention of the subject. To assess these objectives, 95 out of over 150 medical and dental students who expressed willingness to be part of the study were recruited and divided into a Game group and a Non-game group. A pretest written examination was given to both groups, participants in the Game group were allowed to play the game for ten days, after which a post-test examination was also given. A 20-item questionnaire rated on a three-point scale to access student's perception of the game was given to the game group. The post-test scores of the game group were significantly higher (P‚ÄČ<‚ÄČ0.05) than those of the non-game counterparts. Also the post-test score of the game based group was significantly better (P‚ÄČ<‚ÄČ0.05) than their pretest. The students in their feedback noted in very high proportions that the game was interesting, highly informative, encouraged team work, improved their attitude, and perception to gross anatomy. PMID:23878076

  4. Softball Games Bring NCI and Leidos Biomed Employees Together | Poster

    Cancer.gov

    NCI and Leidos Biomed employees took to the fields at Nallin Pond for the third annual slow-pitch softball games on August 26. The series attracted 54 employees who were divided into four teams, Red, Blue, Gray, and White, and they were cheered on by about 40 enthusiastic spectators. In the first set of games, the Gray team defeated the Blue team, 15‚Äď8, and the White team pulled out a win against the Red team, 17‚Äď15. After a brief rest, the two winning teams and the two losing teams faced each other in a second set of games. On Field 1, the ‚Äúwinners‚ÄĚ match-up of the Gray and White teams was a nail biter, with a close score throughout the game. Daylight was a factor, however, and the team captains decided to call the game for safety reasons. With a lead of 15 to 13, the Gray team was declared the overall winner.

  5. Controlling the vocabulary for anatomy.

    PubMed

    Baud, R H; Lovis, C; Rassinoux, A M; Ruch, P; Geissbuhler, A

    2002-01-01

    When confronted with the representation of human anatomy, natural language processing (NLP) system designers are facing an unsolved and frequent problem: the lack of a suitable global reference. The available sources in electronic format are numerous, but none fits adequately all the constraints and needs of language analysis. These sources are usually incomplete, difficult to use or tailored to specific needs. The anatomist's or ontologist's view does not necessarily match that of the linguist. The purpose of this paper is to review most recognized sources of knowledge in anatomy usable for linguistic analysis. Their potential and limits are emphasized according to this point of view. Focus is given on the role of the consensus work of the International Federation of Associations of Anatomists (IFAA) giving the Terminologia Anatomica. PMID:12463780

  6. Cancer Molecular Analysis Project: weaving a rich cancer research tapestry.

    PubMed

    Buetow, Kenneth H; Klausner, Richard D; Fine, Howard; Kaplan, Richard; Singer, Dinah S; Strausberg, Robert L

    2002-05-01

    The Cancer Molecular Analysis Project (CMAP) of the NCI is integrating diverse cancer research data to elucidate fundamental etiologic processes, enable development of novel therapeutic approaches, and facilitate the bridging of basic and clinical science. PMID:12086845

  7. NCI-60 Cell Line Screening: A Radical Departure in its Time.

    PubMed

    Chabner, Bruce A

    2016-05-01

    The year 2015 marked the 30th anniversary of National Cancer Institute's (NCI's) initial effort to establish a human cell line panel as the basis for discovering new cancer drugs. At its inception, the NCI-60 panel was a controversial departure, born of frustration with previous efforts that employed murine tumors and grounded in the hope that the biology of human tumors was diverse and somehow quite different than the murine leukemia used for the previous 30 years. And while the NCI-60 has not revolutionized cancer drug discovery in terms of the new drugs that resulted, it represents a turning point in the philosophy and practice of cancer drug research. PMID:26755050

  8. NCI Takes Back the Defelice Cup at Ninth Annual Golf Tournament | Poster

    Cancer.gov

    By Ashley DeVine, Staff Writer After being down by a point in the morning, NCI reclaimed the Defelice Cup trophy from Leidos Biomedical Research, with a final score of 12 ¬Ĺ to 11 ¬Ĺ, at the ninth annual Ronald H. Defelice Golf Tournament, held Oct. 13. ‚ÄúThe tightest matches in the nine-year history of this cup competition resulted in a narrow victory for NCI and allowed NCI to take a 5‚Äď4 victory total,‚ÄĚ said Denny Dougherty, one of the team captains for Leidos Biomed and a retired senior subcontracts advisor at what was formerly SAIC-Frederick.

  9. [Functional dental anatomy and amalgam].

    PubMed

    Tavernier, B; Colon, P

    1989-01-01

    Very often, the functional dental anatomy are reflected during the rehabilitation of posterior quadrants. However, the placement, the shaping in correct relation of the different dental components are indispensable conditions to respect, in order to achieve an adequate integration of the restoration within the neuro-muscular system. A clinical protocol is proposed in order to reconcile the anatomical and biological prerequisite and the setting time of modern alloys. PMID:2633261

  10. Anatomy of the infant head

    SciTech Connect

    Bosma, J.F.

    1986-01-01

    This text is mainly an atlas of illustration representing the dissection of the head and upper neck of the infant. It was prepared by the author over a 20-year period. The commentary compares the anatomy of the near-term infant with that of a younger fetus, child, and adult. As the author indicates, the dearth of anatomic information about postnatal anatomic changes represents a considerable handicap to those imaging infants. In part 1 of the book, anatomy is related to physiologic performance involving the pharynx, larynx, and mouth. Sequential topics involve the regional anatomy of the head (excluding the brain), the skeleton of the cranium, the nose, orbit, mouth, larynx, pharynx, and ear. To facilitate use of this text as a reference, the illustrations and text on individual organs are considered separately (i.e., the nose, the orbit, the eye, the mouth, the larynx, the pharynx, and the ear). Each part concerned with a separate organ includes materials from the regional illustrations contained in part 2 and from the skeleton, which is treated in part 3. Also included in a summary of the embryologic and fetal development of the organ.

  11. Hip: Anatomy and US technique

    PubMed Central

    Molini, L.; Precerutti, M.; Gervasio, A.; Draghi, F.; Bianchi, S.

    2011-01-01

    Ultrasound (US) has always had a relatively limited role in the evaluation of the hip due to the deep location of this joint. However, many hip diseases are well detectable at US, but before approaching such a study it is necessary to be thoroughly familiar with the normal anatomy and related US images. The study technique is particularly important as optimization of various parameters is required, such as probe frequency, focalization, positioning of the probe, etc. Also the patientís position is important, as it varies according to the area requiring examination. For the study of the anterior structures, the patient should be in the supine position; for the medial structures, the leg should be abducted and rotated outward with the knee flexed; for the lateral structures, the patient should be in the controlateral decubitus position; for the posterior structures the patient must be in the prone position. US study of the hip includes assessment of the soft tissues, tendons, ligaments and muscles, and also of the bone structures, joint space and serous bursae. The purpose of this article is to review the normal anatomy of the hip as well as the US anatomy of this joint. PMID:23397030

  12. Orientation lesson in anatomy education.

    PubMed

    Saylam, Canan; Coskunol, H

    2005-03-01

    Dissection of a human body during an anatomy course raises questions about invasion of privacy, cadaver sources, dying and death for medical students. The technical orientation in any medical education process tends to motivate students towards a purely biological view of the human body. An orientation lesson was performed, including technical instructions, with particular emphasis on how to deal with emotions. Two hundred and forty-two second-year students were asked to complete a questionnaire and two State-Trait Anxiety Inventory (STAI) self-reports. One hundred and two students participated in an orientation lesson (group A) and 140 students did not (group B). Data were analyzed using SPSS. The t-test and chi-square test were used to evaluate differences between the groups. Group A students showed significantly better performance in both a verbal anatomy examination and multiple-choice test than group B students (p=0.001). There were no differences between group A and B students in the state and trait anxiety levels, willingness to donate their body or organs, belief in life after death, social activity or gender. The goal of including consideration of psychosocial factors in an anatomy course would allow students a thoughtful interpretation of their laboratory experience in the context of their professional development as physicians. PMID:15517261

  13. Hip: Anatomy and US technique.

    PubMed

    Molini, L; Precerutti, M; Gervasio, A; Draghi, F; Bianchi, S

    2011-06-01

    Ultrasound (US) has always had a relatively limited role in the evaluation of the hip due to the deep location of this joint. However, many hip diseases are well detectable at US, but before approaching such a study it is necessary to be thoroughly familiar with the normal anatomy and related US images. The study technique is particularly important as optimization of various parameters is required, such as probe frequency, focalization, positioning of the probe, etc. Also the patient's position is important, as it varies according to the area requiring examination. For the study of the anterior structures, the patient should be in the supine position; for the medial structures, the leg should be abducted and rotated outward with the knee flexed; for the lateral structures, the patient should be in the controlateral decubitus position; for the posterior structures the patient must be in the prone position. US study of the hip includes assessment of the soft tissues, tendons, ligaments and muscles, and also of the bone structures, joint space and serous bursae. The purpose of this article is to review the normal anatomy of the hip as well as the US anatomy of this joint. PMID:23397030

  14. Surgical anatomy of the biliary tract

    PubMed Central

    2008-01-01

    An intimate knowledge of the morphological, functional, and real anatomy is a prerequisite for obtaining optimal results in the complex surgery of extra and intrahepatic cholangiocarcinoma. A complete presentation of the surgical anatomy of the bile ducts includes study of the liver, hepatic surface, margins, and scissures. The frequent variations from the normal anatomy are described and an overview of the blood supply and lymphatics of the biliary tract is presented. PMID:18773059

  15. Anatomy of Ursa Majoris

    NASA Astrophysics Data System (ADS)

    Karachentsev, I. D.; Nasonova, O. G.; Courtois, H. M.

    2013-03-01

    A nearby friable cloud in Ursa Majoris contains 270 galaxies with radial velocities 500 < VLG < 1500 km s-1 inside the area of RA = [11^h. 0, 13^h. 0] and Dec. = [ + 40į, +60į]. At present, 97 galaxies of them have individual distance estimates. We use these data to clarify the structure and kinematics of the UMa complex. According to Makarov & Karachentsev, most of the UMa galaxies belong to seven bound groups, which have the following median parameters: velocity dispersion of 58 km s-1, harmonic projected radius of 300 kpc, virial mass of 2 ◊ 1012 M? and virial mass-to-K-band luminosity ratio of 27 M?/L?. Almost a half of the UMa cloud population are gas-rich dwarfs (Ir, Im, BCD) with active star formation seen in the GALEX UV-survey. The UMa groups reside within 15-19 Mpc from us, being just at the same distance as the Virgo cluster. The total virial mass of the UMa groups is 4 ◊ 1013 M?, yielding the average density of dark matter in the UMa cloud to be ?m = 0.08, i.e. a factor of 3 lower than the cosmic average. This is despite the fact that the UMa cloud resides in a region of the Universe that is an apparent overdensity. A possible explanation for this is that most mass in the Universe lies in the empty space between clusters. Herewith, the mean distances and velocities of the UMa groups follow nearly undisturbed Hubble flow without a sign of the `Z-wave' effect caused by infall towards a massive attractor. This constrains the total amount of dark matter between the UMa groups within the cloud volume.

  16. NCI/EPA AGRICULTURAL HEALTH STUDY (AHS): DEVELOPMENT OF THE BIOMARKER QUESTIONNAIRE

    EPA Science Inventory

    The National Cancer Institute (NCI), the Environmental Protection Agency (EPA), ind the National Institute of Environmental Health Sciences (NIEHS) have planned a long-term prospective epidemiologic study of men, women, and dependent children in agricultural areas to identify and...

  17. SOP: Thawing, Propagation and Cryopreservation of NCI-PBCF-CCL227 (SW620)

    Cancer.gov

    Table of Contents 1. BACKGROUND INFORMATION ON SW620 CELL LINE ...................................................................3 2. GENERAL INFORMATION FOR THE THAWING, PROPAGATING AND CRYOPRESERVING OF NCI-PBCF-CCL227 (SW620) ........................................................................................................................3 3. REAGENTS ...........................................................................................................................................5 A.

  18. NCI Requests Targets for Monoclonal Antibody Production and Characterization - Office of Cancer Clinical Proteomics Research

    Cancer.gov

    In an effort to provide well-characterized monoclonal antibodies to the scientific community, NCI's Antibody Characterization Program requests cancer-related protein targets for affinity production and distribution.

  19. NCI Launches Proteomics Assay Portal - Office of Cancer Clinical Proteomics Research

    Cancer.gov

    In a paper recently published by the journal Nature Methods, Investigators from the National Cancer Institute’s Clinical Proteomic Tumor Analysis Consortium (NCI-CPTAC) announced the launch of a proteomics Assay Portal for multiple reaction monitoring-mass

  20. NCI and the Chinese Academy of Medical Sciences Sign Statement of Intent

    Cancer.gov

    Today the National Cancer Institute (NCI) and the Cancer Institute/Hospital of the Chinese Academy of Medical Sciences (CICAMS) signed a statement of intent to share an interest in fostering collaborative biomedical research in oncology and a common goal

  1. Agenda for the Second NCI Epidemiology Leadership Workshop: Understudied Rare Cancers

    Cancer.gov

    Skip to Main Content at the National Institutes of Health | www.cancer.gov Epidemiology and Genomics Research In NCI's Division of Cancer Control and Population Sciences Search EGRP: Main Menu EGRP Home About the Program Mission & Vision Organizational

  2. 76 FR 66932 - The National Cancer Institute (NCI) Announces the Initiation of a Public Private Industry...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-28

    ... Initiation of a Public Private Industry Partnership on Translation of Nanotechnology in Cancer (TONIC) To Promote Translational Research and Development Opportunities of Nanotechnology-Based Cancer Solutions AGENCY: National Cancer Institute (NCI), Office of Cancer Nanotechnology Research (OCNR),...

  3. 78 FR 53763 - Proposed Collection; 60-day Comment Request Cancer Trials Support Unit (CTSU) (NCI)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-30

    ... Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, 9609 Medical Center Drive... HUMAN SERVICES National Institutes of Health Proposed Collection; 60-day Comment Request Cancer Trials..., the National Cancer Institute (NCI), National Institutes of Health (NIH), will publish...

  4. National Medal of Technology Awarded to NCI Drs. Lowy and Schiller

    Cancer.gov

    President Obama announced that two NCI scientists would be recipients of the National Medal of Technology and Innovation -- the nation's highest honor for technological achievement. The honorees, John Schiller, Ph.D., Laboratory of Cellular Oncology (LCO)

  5. Gardasil¬ģ and Cervarix¬ģ | NCI Technology Transfer Center | TTC

    Cancer.gov

    Vaccine for human papilloma virus (HPV) to protect from cancers Key elements of the technology for Gardasil¬ģ and Cervarix originated from the HPV research of the laboratory of Drs. Douglas Lowy and John Schiller of the NCI.

  6. Anatomy and physiology for nursing students: is problem-based learning effective?

    PubMed

    Mayner, Lidia; Gillham, David; Sansoni, Julita

    2013-01-01

    This study investigated whether problem-based learning (PBL) was an effective strategy for nursing students learning anatomy and physiology. Anatomy and physiology are subject areas that have posed long standing difficulty for nursing students. Since anatomy and physiology underpin clinical decision making it is important that nursing students are able to understand and retain this knowledge and apply it to practice. Problem-based learning offers potential advantages for teaching anatomy and physiology as clinical cases can provide the impetus for student problem solving. This project trialled a simple PBL scenario and investigated students' response to the task of problem solving in a laboratory setting adapted to simulate a hospital ward. The study found students learn better, retain the knowledge and merge theory with simulated practice when a PBL teaching mode is used. While PBL was effective, blended, web based and hybrid PBL models warrant investigation. PMID:24083499

  7. Body-Painting: A Tool Which Can Be Used to Teach Surface Anatomy

    PubMed Central

    Nanjundaiah, Komala; Chowdapurkar, Sheshgiri

    2012-01-01

    Introduction The primary method of learning the surface anatomy is by making the students mark structures on mummified bodies. The students feel that learning the surface anatomy on mummified cadavers is not interesting. The present project on learning the surface anatomy through the body painting method was undertaken to evoke interest among the students. Materials and Methods Physiotherapy and dental undergraduate students who volunteered were involved in this study. A few surface anatomy classes were conducted by using the traditional method and a few more by using the body painting exercise. Non toxic body paints of various colours and brushes of different sizes were used for the body painting. Results A feedback was obtained from the students by using a structured questionnaire. The students opined that the body painting method was advantageous to them in learning the human anatomy. They also felt that they could have more practice sessions in any setting other than in the classroom and that they did not need to rely upon the mummified bodies. They described the body painting method as self explanatory, which gave them the feel of live structures. Conclusion This project was successful in achieving its objectives as the students felt that the method was exciting, with lots of fun during the learning. The body painting method was well accepted by the students as an effective method for learning the surface and the clinical anatomy. PMID:23205358

  8. NCI at Frederick Team Receives 2014 HHS Green Champions Award | Poster

    Cancer.gov

    A team of NCI and Leidos Biomedical Research employees at NCI at Frederick received the Energy and Fleet Management Award, one of the 2014 Department of Health and Human Services (HHS) Green Champions Awards, for comparing the costs and energy usage of two -80¬įC freezer technologies. This was the first scientific study to be jointly conducted by Leidos Biomedical Research‚Äôs Applied and Developmental Research Directorate (ADRD) and Facilities Maintenance and Engineering Directorate (FME).¬†¬†

  9. The effect of jet and DBD plasma on NCI-78 blood cancer cells

    NASA Astrophysics Data System (ADS)

    Kaushik, Nagendra K.; Kaushik, Neha; Choi, Eun Ha

    2013-06-01

    In this study we describe the effects of a nonthermal jet and dielectric barrier discharge (DBD) plasma on the T98G brain cancer cell line. The results of this study reveal that the jet and DBD plasma inhibits NCI-78 blood cancer cells growth efficiently with the loss of metabolic viability of cells. The main goal of this study is to induce cell death in NCI-78 blood cancer cells by the toxic effect of jet and DBD plasma.

  10. NCI: SBIR & STTR - Past Funding Opportunities - Contracts - 229 Development of Molecular Pharmacodynamic Assays for Targeted Therapies

    Cancer.gov

    The NCI requests that qualified small businesses submit proposals to develop pharmacodynamic assays for measuring a number of high-priority molecular targets. (For a list of the targets of interest to NCI, please click here). The short term goal of this contract is to develop new rigorous, validated assays to measure molecular-level response to treatment in conjunction with preclinical development of new candidate therapeutic agents.

  11. NCI: SBIR & STTR - Find Funding - Contracts - 271 Development of Molecular Pharmacodynamic Assays for Targeted Therapies

    Cancer.gov

    The NCI requests that qualified small businesses submit proposals to develop pharmacodynamic assays for measuring drug response of a number of high-priority molecular targets. A list of the targets of interest to NCI is shown below. The short-term goal of this contract topic is to develop new robust, validated assays to measure molecular-level responses to treatment in conjunction with preclinical development of new candidate therapeutic agents.

  12. NCI at Frederick Team Receives 2014 HHS Green Champions Award | Poster

    Cancer.gov

    A team of NCI and Leidos Biomedical Research employees at NCI at Frederick received the Energy and Fleet Management Award, one of the 2014 Department of Health and Human Services (HHS) Green Champions Awards, for comparing the costs and energy usage of two -80įC freezer technologies. This was the first scientific study to be jointly conducted by Leidos Biomedical Researchís Applied and Developmental Research Directorate (ADRD) and Facilities Maintenance and Engineering Directorate (FME).††

  13. Surface anatomy and anatomical planes in the adult turkish population.

    PubMed

    Uzun, C; Atman, E D; Ustuner, E; Mirjalili, S A; Oztuna, D; Esmer, T S

    2016-03-01

    Surface anatomy and anatomical planes are widely used in education and clinical practice. The planes are largely derived from cadaveric studies and their projections on the skin show discrepancies between and within anatomical reference textbooks. In this study, we reassessed the accuracy of common thoracic and abdominopelvic anatomical planes using computed tomography (CT) imaging in the live adult Turkish population. After patients with distorting pathologies had been excluded, CT images of 150 supine patients at the end tidal inspiration were analyzed. Sternal angle, transpyloric, subcostal, supracristal and pubic crest planes and their relationships to anatomical structures were established by dual consensus. The tracheal bifurcation, azygos vein/superior vena cava (SVC) junction and pulmonary bifurcation were usually below the sternal angle while the concavity of the aortic arch was generally within the plane. The tip of the tenth rib, the superior mesenteric artery and the portal vein were usually within the transpyloric plane while the renal hila and the fundus of the gallbladder were below it. The inferior mesenteric artery was below the subcostal plane and the aortic bifurcation was below the supracristal plane in most adults. Projectional surface anatomy is fundamental to medical education and clinical practice. Modern cross-sectional imaging techniques allow large groups of live patients to be examined. Classic textbook information regarding anatomy needs to be reviewed and updated using the data gathered from these recent studies, taking ethnic differences into consideration. Clin. Anat. 29:183-190, 2016. © 2015 Wiley Periodicals, Inc. PMID:26403267

  14. Gross anatomy of network security

    NASA Technical Reports Server (NTRS)

    Siu, Thomas J.

    2002-01-01

    Information security involves many branches of effort, including information assurance, host level security, physical security, and network security. Computer network security methods and implementations are given a top-down description to permit a medically focused audience to anchor this information to their daily practice. The depth of detail of network functionality and security measures, like that of the study of human anatomy, can be highly involved. Presented at the level of major gross anatomical systems, this paper will focus on network backbone implementation and perimeter defenses, then diagnostic tools, and finally the user practices (the human element). Physical security measures, though significant, have been defined as beyond the scope of this presentation.

  15. Functional anatomy of the nose.

    PubMed

    Koppe, Thomas; Giotakis, Evangelos I; Heppt, Werner

    2011-04-01

    The human nose is a very complex entity with a great amount of variation among and within different human populations. Even though the morphology of the nasal pyramid and its soft tissue coverage is principally known, a standardized nomenclature does not yet exist. The past two decades have witnessed a considerable increase of new studies on the functional morphology of the external nasal anatomy. Detailed anatomic and clinical knowledge about the external nose is a prerequisite for successful rhinosurgery, thus this report deals with the basic structures necessary for functional and aesthetic rhinoplasty. PMID:21404156

  16. Anatomy online: presentation of a detailed WWW atlas of human gross anatomy--reference for medical education.

    PubMed

    Jastrow, Holger; Vollrath, Lutz

    2002-11-01

    We present an online anatomy atlas based on the Visible Human Project (VHP) of the US National Library of Medicine. The objective is to provide original unlabeled as well as labeled sections of the human body of high quality and resolution on the Internet, for use in basic and continuing medical education. For a representative overview of the body, 370 axial sections were selected from the male and female data base of the VHP with special regard to regions of clinical interest. Each section is accompanied by its corresponding computer tomography (CT) image and, if available, magnetic resonance images (MRI) for quick and easy comparison of morphologic and radiologic structures. The sections can be studied unlabeled or labeled according to the current Terminologia Anatomica. A linked vocabulary with more than 850 terms explains the labeling. Animations of the sections as well as of CT and MR images allow for further visualization of the topographic relationships of anatomical structures. The responses to the project indicate that students and physicians regard the Internet Atlas of Human Gross Anatomy as a most useful aid for learning and reviewing anatomical details. The atlas is accessible on: http://www.uni-mainz.de/FB/Medizin/Anatomie/workshop/vishuman/Eready.html. PMID:12373730

  17. Data Mining the NCI60 to Predict Generalized Cytotoxicity

    PubMed Central

    Lee, Adam C.; Shedden, Kerby; Rosania, Gustavo R.; Crippen, Gordon M.

    2008-01-01

    Elimination of cytotoxic compounds in the early and later stages of drug discovery can help reduce the costs of research and development. Through the application of principal components analysis (PCA), we were able to data mine and prove that ?89% of the total log GI50 variance is due to the non-specific cytotoxic nature of substances. Furthermore, PCA led to the identification of groups of structurally unrelated substances showing very specific toxicity profiles, such as a set of 45 substances toxic only to the Leukemia_SR cancer cell line. In an effort to predict non-specific cytotoxicity based on the mean log GI50, we created a decision tree using MACCS keys that can correctly classify over 83% of the substances as cytotoxic/non-cytotoxic in silico, based on the cutoff of mean log GI50 = ?5.0. Finally, we have established a linear model using least squares in which 9 of the 59 available NCI60 cancer cell lines can be used to predict the mean log GI50. The model has R2=0.99 and root mean square deviation between the observed and calculated mean log GI50 (RMSE) = 0.09. Our predictive models can be applied to flag generally cytotoxic molecules in virtual and real chemical libraries, thus saving time and effort. PMID:18588283

  18. Frank Netter's Legacy: Interprofessional Anatomy Instruction

    ERIC Educational Resources Information Center

    Niekrash, Christine E.; Copes, Lynn E.; Gonzalez, Richard A.

    2015-01-01

    Several medical schools have recently described new innovations in interprofessional interactions in gross anatomy courses. The Frank H. Netter MD School of Medicine at Quinnipiac University in Hamden, CT has developed and implemented two contrasting interprofessional experiences in first-year medical student gross anatomy dissection laboratories:Ö

  19. Frank Netter's Legacy: Interprofessional Anatomy Instruction

    ERIC Educational Resources Information Center

    Niekrash, Christine E.; Copes, Lynn E.; Gonzalez, Richard A.

    2015-01-01

    Several medical schools have recently described new innovations in interprofessional interactions in gross anatomy courses. The Frank H. Netter MD School of Medicine at Quinnipiac University in Hamden, CT has developed and implemented two contrasting interprofessional experiences in first-year medical student gross anatomy dissection laboratories:…

  20. Anatomy Education Faces Challenges in Pakistan

    ERIC Educational Resources Information Center

    Memon, Ismail K.

    2009-01-01

    Anatomy education in Pakistan is facing many of the same challenges as in other parts of the world. Roughly, a decade ago, all medical and dental colleges in Pakistan emphasized anatomy as a core basic discipline within a traditional medical science curriculum. Now institutions are adopting problem based learning (PBL) teaching philosophies, and…

  1. [The oldest painting of an anatomy lesson].

    PubMed

    Keeman, Hans

    2011-01-01

    The Amsterdam Historical Museum has a large collection of paintings of anatomy lessons, painted when surgeons followed the popular sixteenth century trend for group portraits. The very first, a painting of an anatomy lesson given by Sebastiaen Egbertsz de Vrij, was painted by Aert Pietersz in 1601-1603. PMID:21291580

  2. Shark Attack! Sinking Your Teeth into Anatomy.

    ERIC Educational Resources Information Center

    House, Herbert

    2002-01-01

    Presents a real life shark attack story and studies arm reattachment surgery to teach human anatomy. Discusses how knowledge of anatomy can be put to use in the real world and how the arm functions. Includes teaching notes and suggestions for classroom management. (YDS)

  3. Anatomy Education Faces Challenges in Pakistan

    ERIC Educational Resources Information Center

    Memon, Ismail K.

    2009-01-01

    Anatomy education in Pakistan is facing many of the same challenges as in other parts of the world. Roughly, a decade ago, all medical and dental colleges in Pakistan emphasized anatomy as a core basic discipline within a traditional medical science curriculum. Now institutions are adopting problem based learning (PBL) teaching philosophies, andÖ

  4. The Human Anatomy Teacher-Scholar: Meeting the Expectations of Educational Outcomes Research, Course Content Innovation, and Textbook Innovation for Educational Scholarship

    ERIC Educational Resources Information Center

    Eckel, Christine Marie

    2009-01-01

    A human anatomy teacher-scholar is a scholar whose area of expertise includes content knowledge of the anatomical sciences (gross anatomy, histology, embryology, and/or neuroanatomy) and whose research interests and focus are centered in medical educational outcomes. The projects described in this dissertation represent endeavors I engaged in to…

  5. The Human Anatomy Teacher-Scholar: Meeting the Expectations of Educational Outcomes Research, Course Content Innovation, and Textbook Innovation for Educational Scholarship

    ERIC Educational Resources Information Center

    Eckel, Christine Marie

    2009-01-01

    A human anatomy teacher-scholar is a scholar whose area of expertise includes content knowledge of the anatomical sciences (gross anatomy, histology, embryology, and/or neuroanatomy) and whose research interests and focus are centered in medical educational outcomes. The projects described in this dissertation represent endeavors I engaged in toÖ

  6. The history and illustration of anatomy in the Middle Ages.

    PubMed

    Gurunluoglu, Raffi; Gurunluoglu, Aslin; Williams, Susan A; Cavdar, Safiye

    2013-11-01

    This article reviews the influence of key figures on the pictorial representation of anatomy and the evolution of anatomical illustration during the Middle Ages until the time of the Renaissance, based on medical history books, journals and ancient medical books. During the early period in the Middle Ages, most illustrations were traditional drawings of emblematic nature, oftentimes unrealistic, not only because the precise knowledge of anatomy was lacking but also because the objective was to elucidate certain principles for teaching purposes. Five figure-series that came down to us through ancient manuscripts and textbooks represent the best examples of such traditional illustrations. With the advent of human dissection in the 13th and 14th centuries, a significant transformation in the depiction of anatomy began to project the practice of human dissection, as we see in the works of Mondino de Luzzi, Henri de Mondeville and Guido de Vigevano. After the invention of book printing in the second half of the 15th century, the reproduction of books was commonly practised and the woodcut made multiplication of pictures easier. Peter of Abano, Hieronymous Brunschwig, Johannes de Ketham, Johannes Peyligk, Gregory Reisch, Magnus Hundt, Laurentius Phryesen and many more included several anatomical illustrations in their treatises that demonstrated the development of anatomical illustration during the later Middle Ages. PMID:24585828

  7. Frank Netter's legacy: Interprofessional anatomy instruction.

    PubMed

    Niekrash, Christine E; Copes, Lynn E; Gonzalez, Richard A

    2015-01-01

    Several medical schools have recently described new innovations in interprofessional interactions in gross anatomy courses. The Frank H. Netter MD School of Medicine at Quinnipiac University in Hamden, CT has developed and implemented two contrasting interprofessional experiences in first-year medical student gross anatomy dissection laboratories: long-term, informal visits by pathologists' assistant students who work with the medical students to identify potential donor pathologies, and a short-term, formal visit by fourth-year dental students who teach craniofacial anatomy during the oral cavity dissection laboratory. A survey of attitudes of participants was analyzed and suggest the interprofessional experiences were mutually beneficial for all involved, and indicate that implementing multiple, contrasting interprofessional interactions with different goals within a single course is feasible. Two multiple regression analyses were conducted to analyze the data. The first analysis examined attitudes of medical students towards a pathologists' assistant role in a health care team. The question addressing a pathologists' assistant involvement in the anatomy laboratory was most significant. The second analysis examined attitudes of medical students towards the importance of a good foundation in craniofacial anatomy for clinical practice. This perceived importance is influenced by the presence of dental students in the anatomy laboratory. In both instances, the peer interprofessional interactions in the anatomy laboratory resulted in an overall positive attitude of medical students towards pathologists' assistant and dental students. The consequences of these interactions led to better understanding, appreciation and respect of the different professionals that contribute to a health care team. PMID:26014811

  8. Mutation analysis of 24 known cancer genes in the NCI-60 cell line set

    PubMed Central

    Ikediobi, Ogechi N.; Davies, Helen; Bignell, Graham; Edkins, Sarah; Stevens, Claire; OíMeara, Sarah; Santarius, Thomas; Avis, Tim; Barthorpe, Syd; Brackenbury, Lisa; Buck, Gemma; Butler, Adam; Clements, Jody; Cole, Jennifer; Dicks, Ed; Forbes, Simon; Gray, Kristian; Halliday, Kelly; Harrison, Rachel; Hills, Katy; Hinton, Jonathan; Hunter, Chris; Jenkinson, Andy; Jones, David; Kosmidou, Vivienne; Lugg, Richard; Menzies, Andrew; Mironenko, Tatiana; Parker, Adrian; Perry, Janet; Raine, Keiran; Richardson, David; Shepherd, Rebecca; Small, Alex; Smith, Raffaella; Solomon, Helen; Stephens, Philip; Teague, Jon; Tofts, Calli; Varian, Jennifer; Webb, Tony; West, Sofie; Widaa, Sara; Yates, Andy; Reinhold, William; Weinstein, John N.; Stratton, Michael R.; Futreal, P. Andrew; Wooster, Richard

    2009-01-01

    The panel of 60 human cancer cell lines (the NCI-60) assembled by the National Cancer Institute for anticancer drug discovery is a widely used resource. The NCI-60 has been characterized pharmacologically and at the molecular level more extensively than any other set of cell lines. However, no systematic mutation analysis of genes causally implicated in oncogenesis has been reported. This study reports the sequence analysis of 24 known cancer genes in the NCI-60 and an assessment of 4 of the 24 genes for homozygous deletions. One hundred thirty-seven oncogenic mutations were identified in 14 (APC, BRAF, CDKN2, CTNNB1, HRAS, KRAS, NRAS, SMAD4, PIK3CA, PTEN, RB1, STK11, TP53, and VHL) of the 24 genes. All lines have at least one mutation among the cancer genes examined, with most lines (73%) having more than one. Identification of those cancer genes mutated in the NCI-60, in combination with pharmacologic and molecular profiles of the cells, will allow for more informed interpretation of anticancer agent screening and will enhance the use of the NCI-60 cell lines for molecularly targeted screens. PMID:17088437

  9. Art, antiquarianism and early anatomy.

    PubMed

    Guest, Clare E L

    2014-12-01

    Discussions of the early relationship between art and anatomy are shaped by Vasari's account of Florentine artists who dissected bodies in order to understand the causes of movement, and the end of movement in action. This account eclipses the role of the study of antiquities in Renaissance anatomical illustration. Beyond techniques of presentation, such as sectioning and analytic illustration, or a preoccupation with the mutilated fragment, antiquarianism offered a reflection on the variant and the role of temperament which could be adapted for anatomical purposes. With its play on ambiguities of life and death, idealisation and damage, antiquarianism also provided a way of negotiating the difficulties of content inherent in anatomical illustration. As such, it goes beyond exclusively historical interest to provoke reflection on the modes, possibilities and humane responsibilities of medical illustration. PMID:24696510

  10. Venous anatomy of the thumb.

    PubMed

    Matloub, H S; Strathy, K M; Sanger, J R; Yousif, N J

    1991-11-01

    The venous anatomy of 20 thumbs (10 pairs) was detailed by latex injection. The thumbs were studied on the dorsal, palmar, radial, and ulnar surfaces. Characteristic patterns were found; these included a dominant longitudinal network, palmar veins within the pulp, oblique veins at the interphalangeal joint on the radial side, and a web space vein. A layered vascular pattern with a superficial fine network overlying a deeper system was noted. Cross sections were taken at the metacarpophalangeal joint and at the proximal and distal phalanges. The distribution of the vessels in cross section reveals consistent dorsal veins at all levels, as well as palmar veins distal to the interphalangeal joint in all thumbs. Palmar veins were present over the length of the proximal phalanx in more than 65% of the thumbs. PMID:1748753

  11. Evolutions equations in computational anatomy.

    PubMed

    Younes, Laurent; Arrate, Felipe; Miller, Michael I

    2009-03-01

    One of the main purposes in computational anatomy is the measurement and statistical study of anatomical variations in organs, notably in the brain or the heart. Over the last decade, our group has progressively developed several approaches for this problem, all related to the Riemannian geometry of groups of diffeomorphisms and the shape spaces on which these groups act. Several important shape evolution equations that are now used routinely in applications have emerged over time. Our goal in this paper is to provide an overview of these equations, placing them in their theoretical context, and giving examples of applications in which they can be used. We introduce the required theoretical background before discussing several classes of equations of increasingly complexity. These equations include energy minimizing evolutions deriving from Riemannian gradient descent, geodesics, parallel transport and Jacobi fields. PMID:19059343

  12. An atlas of radiological anatomy

    SciTech Connect

    Weir, J.; Abrahams, P.

    1986-01-01

    This book contains a wealth of radiologic images of normal human anatomy; plain radiographs, contrast-enhanced radiographs, and computed tomography (CT) scans. There are 18 pages of magnetic resonance (MR) images, most on the brain and spinal cord, so that there are only two pages on MR imaging of the heart and two pages on abdominal and pelvic MR imaging. Twelve pages of ultrasound (US) images are included. This book has the radiologic image paired with an explanatory drawing; the image is on the left with a paragraph or two of text, and the drawing is on the right with legends. This book includes images of the brain and spinal cord obtained with arteriography, venography, myelography, encephalography, CT, and MR imaging.

  13. High precision anatomy for MEG?

    PubMed Central

    Troebinger, Luzia; Lůpez, Josť David; Lutti, Antoine; Bradbury, David; Bestmann, Sven; Barnes, Gareth

    2014-01-01

    Precise MEG estimates of neuronal current flow are undermined by uncertain knowledge of the head location with respect to the MEG sensors. This is either due to head movements within the scanning session or systematic errors in co-registration to anatomy. Here we show how such errors can be minimized using subject-specific head-casts produced using 3D printing technology. The casts fit the scalp of the subject internally and the inside of the MEG dewar externally, reducing within session and between session head movements. Systematic errors in matching to MRI coordinate system are also reduced through the use of MRI-visible fiducial markers placed on the same cast. Bootstrap estimates of absolute co-registration error were of the order of 1†mm. Estimates of relative co-registration error were <†1.5†mm between sessions. We corroborated these scalp based estimates by looking at the MEG data recorded over a 6†month period. We found that the between session sensor variability of the subject's evoked response was of the order of the within session noise, showing no appreciable noise due to between-session movement. Simulations suggest that the between-session sensor level amplitude SNR improved by a factor of 5 over conventional strategies. We show that at this level of coregistration accuracy there is strong evidence for anatomical models based on the individual rather than canonical anatomy; but that this advantage disappears for errors of greater than 5†mm. This work paves the way for source reconstruction methods which can exploit very high SNR signals and accurate anatomical models; and also significantly increases the sensitivity of longitudinal studies with MEG. PMID:23911673

  14. [Surgical anatomy of the nose. II].

    PubMed

    Adant, J P; Bluth, F; Nelissen, X; Fissette, J

    1998-10-01

    Over recent years, an increasing number of papers are published in the international literature about nasal anatomy, probably because of the growing popularity of open rhinoplasty. New concepts and new anatomical entities have been established without any equivalent in the French literature. This paper reviews the most recent concepts of surgical anatomy of the nose and proposes a French terminology for several concepts developed in the international literature (e.g. supratip breakpoint). In this second part, the surgical anatomy of the nasal cavities is analyzed together with a glossary including the main concepts, some of them unpublished in the French literature. PMID:9882890

  15. Clinical aspects of rodent dental anatomy.

    PubMed

    Crossley, D A

    1995-12-01

    The order Rodentia is vast, encompassing a large number of species with significant anatomical variations developed during natural adaptation to differing habitats. Many veterinarians have little knowledge of the anatomy of species other than the commoner domestic large herbivores and small carnivores. Clinicians require a basic knowledge of the relevant anatomy of species they are likely to be asked to treat. This article provides sufficient working knowledge of the oral and dental anatomy of those rodents commonly kept as pets to enable veterinarians to interpret clinical and radiographic findings when investigating suspected dental disease. PMID:9693638

  16. The development, assessment and validation of virtual reality for human anatomy instruction

    NASA Technical Reports Server (NTRS)

    Marshall, Karen Benn

    1996-01-01

    This research project seeks to meet the objective of science training by developing, assessing, validating and utilizing VR as a human anatomy training medium. Current anatomy instruction is primarily in the form of lectures and usage of textbooks. In ideal situations, anatomic models, computer-based instruction, and cadaver dissection are utilized to augment traditional methods of instruction. At many institutions, lack of financial resources limits anatomy instruction to textbooks and lectures. However, human anatomy is three-dimensional, unlike the one-dimensional depiction found in textbooks and the two-dimensional depiction found on the computer. Virtual reality allows one to step through the computer screen into a 3-D artificial world. The primary objective of this project is to produce a virtual reality application of the abdominopelvic region of a human cadaver that can be taken back to the classroom. The hypothesis is that an immersive learning environment affords quicker anatomic recognition and orientation and a greater level of retention in human anatomy instruction. The goal is to augment not replace traditional modes of instruction.

  17. Analysis of hydrogen-bond interaction potentials from the electron density: Integration of NCI regions

    PubMed Central

    Contreras-GarcŪa, Julia; Yang, Weitao; Johnson, Erin R.

    2013-01-01

    Hydrogen bonds are of crucial relevance to many problems in chemistry biology and materials science. The recently-developed NCI (Non-Covalent Interactions) index enables real-space visualization of both attractive (van der Waals and hydrogen-bonding) and repulsive (steric) interactions based on properties of the electron density It is thus an optimal index to describe the interplay of stabilizing and de-stabilizing contributions that determine stable minima on hydrogen-bonding potential-energy surfaces (PESs). In the framework of density-functional theory energetics are completely determined by the electron density Consequently NCI will be shown to allow quantitative treatment of hydrogen-bond energetics. The evolution of NCI regions along a PES follows a well-behaved pattern which, upon integration of the electron density is capable of mimicking conventional hydrogen-bond interatomic potentials. PMID:21786796

  18. Patient-centered communication in cancer care: the role of the NCI's Cancer Information Service.

    PubMed

    Perocchia, Rosemarie Slevin; Hodorowski, Julie Keany; Williams, Laurie A; Kornfeld, Julie; Davis, Nydia Lassalle; Monroe, Maryann; Bright, Mary Anne

    2011-03-01

    While patient-centered care and the reduction of suffering due to cancer are primary goals of the NCI, improvement in the delivery of patient-centered communication has been identified as a key NCI research priority. As research on patient-centered communication evolves, the potential contributions of programs such as the National Cancer Institute's (NCI) Cancer Information Service (CIS) cannot be overlooked. The purpose of this paper is to describe how the six core functions of patient-clinician communication described in the literature (fostering healing relationships, exchanging information, responding to emotions, managing uncertainty, making decisions and enabling patient-self management) are embedded in the work of the CIS. The communication process used by the CIS to extend the patient-centered communication role of the clinician will be discussed. CIS training and quality management systems will be described. Lastly, suggestions for the role of CIS in future health information delivery and research will be explored. PMID:20532726

  19. NIH and NCI grant-related changes during fiscal years 2014 and 2015

    NASA Astrophysics Data System (ADS)

    Wong, Rosemary S. L.

    2015-03-01

    The 2014 fiscal year (FY) continued to be a challenging one for all federal agencies despite the many Congressional strategies proposed to address the U.S. budget deficit. The Bipartisan Budget Act of 2013 passed by the House and Senate in December 2013 approved a two-year spending bill which cancelled the FY2014 and FY2015 required sequestration cuts (i.e., 4-5% National Institute of Health (NIH)/National Cancer Institute (NCI) budget reduction initiated on March 1, 2013), but extended the sequestration period through FY2023. This bill passage helped minimize any further budget reductions and resulted in a final FY2014 NIH budget of 29.9 billion and a NCI budget of 4.9 billion. Both NIH and NCI worked hard to maintain awarding the same number of NIH/NCI investigator-initiated R01 and exploratory R21 grants funded in FY2014 and similar to the level seen in FY2013 and previous years (see Tables 1 and 2). Since Congress only recently passed the 2015 spending bill in December 16, 2014, the final NIH and NCI budget appropriations for FY2015 remains unknown at this time and most likely will be similar to the FY2014 budget level. The NCI overall success and funding rates for unsolicited investigator-initiated R01 applications remained at 15%, while the success rate for exploratory R21 applications was 12% in FY2014 with similar rates seen in FY2013 (see Tables 1 and 2). The success rate for biomedical research applications in the Photodynamic Therapy and laser research field will be provided for the past few years. NIH provides numerous resources to help inform the extramural biomedical research community of new and current grant applicants about new grant policy changes and the grant submission and review processes.

  20. Making gross anatomy relevant to dental students.

    PubMed

    Guttmann, Geoffrey D; Ma, Terence P; MacPherson, Brian R

    2003-03-01

    This paper describes the curriculum design and enhancements of dental gross anatomy courses at three universities in North America. The greatest problem for gross anatomy faculty is making the regions of the body below the neck relevant to dental students for their future clinical education as well as the longer term dental practice. The proposed solutions demonstrated in the three courses range from satisfying the student's grade and test requirements, such as passing the anatomical sciences section of the National Board Dental Examination Part I, to making the material relevant to clinical dentistry. Strategies to increase relevance include incorporating clinical faculty into the gross anatomy course and integrating dental clinical material into the course. Lastly, pedagogical innovations include peer teaching, the use of the Internet and intranet for examination preparation, and the animation of dental procedures to illustrate relevant anatomy to dentistry. PMID:12665065

  1. Curricular Guidelines for Teaching Dental Anatomy.

    ERIC Educational Resources Information Center

    Okeson, Jeffrey; Buckman, James

    1981-01-01

    Guidelines developed by the Section on Dental Anatomy and Occlusion of the American Association of Dental Schools for use by individual educational institutions as curriculum development aids are provided. (MLW)

  2. Understanding Colds: Anatomy of the Nose

    MedlinePLUS

    ... Colds Prevention Treatment Children Complications Special Features References Common Cold Understanding Colds Anatomy of the Nose The nose ... cm (3/8 inch) per minute. What a Common Cold Is A common cold is an illness caused ...

  3. CPR Instruction in a Human Anatomy Class.

    ERIC Educational Resources Information Center

    Lutton, Lewis M.

    1978-01-01

    Describes how cardiopulmonary resuscitation (CPR) instruction can be included in a college anatomy and physiology course. Equipment and instructors are provided locally by the Red Cross or American Heart Association. (MA)

  4. NCI QuitPal, an App from the National Cancer Institute | NIH MedlinePlus the Magazine

    MedlinePLUS

    ... page please turn Javascript on. NCI QuitPal, an App from the National Cancer Institute Past Issues / Winter ... a cigarette? NCI QuitPal is a free, interactive app for iPhone or iPad that uses proven quit ...

  5. Control del c√°ncer y salud mundial: noticia del Instituto Nacional del C√°ncer (NCI)

    Cancer.gov

    En combinación con una reunión de alto nivel de las Naciones Unidas sobre enfermedades no transmisibles en países en vías de desarrollo, el doctor Harold Varmus, director del NCI, y el doctor Ted L. Trimble, del NCI, han publicado un comentario en Science

  6. BOLD Granger Causality Reflects Vascular Anatomy

    PubMed Central

    Webb, J. Taylor; Ferguson, Michael A.; Nielsen, Jared A.; Anderson, Jeffrey S.

    2013-01-01

    A number of studies have tried to exploit subtle phase differences in BOLD time series to resolve the order of sequential activation of brain regions, or more generally the ability of signal in one region to predict subsequent signal in another region. More recently, such lag-based measures have been applied to investigate directed functional connectivity, although this application has been controversial. We attempted to use large publicly available datasets (FCON 1000, ADHD 200, Human Connectome Project) to determine whether consistent spatial patterns of Granger Causality are observed in typical fMRI data. For BOLD datasets from 1,240 typically developing subjects ages 7‚Äď40, we measured Granger causality between time series for every pair of 7,266 spherical ROIs covering the gray matter and 264 seed ROIs at hubs of the brain‚Äôs functional network architecture. Granger causality estimates were strongly reproducible for connections in a test and replication sample (n=620 subjects for each group), as well as in data from a single subject scanned repeatedly, both during resting and passive video viewing. The same effect was even stronger in high temporal resolution fMRI data from the Human Connectome Project, and was observed independently in data collected during performance of 7 task paradigms. The spatial distribution of Granger causality reflected vascular anatomy with a progression from Granger causality sources, in Circle of Willis arterial inflow distributions, to sinks, near large venous vascular structures such as dural venous sinuses and at the periphery of the brain. Attempts to resolve BOLD phase differences with Granger causality should consider the possibility of reproducible vascular confounds, a problem that is independent of the known regional variability of the hemodynamic response. PMID:24349569

  7. SOP: Thawing, Propagation and Cryopreservation of NCI-PBCF-HTB132 (MDA-MB-468)

    Cancer.gov

    Table of Contents 1. BACKGROUND INFORMATION ON NCI-PBCF-HTB132 (MDA-MB-468) CELL LINE .....................3 2. GENERAL INFORMATION FOR THE THAWING, PROPAGATING AND CRYOPRESERVING OF NCI-PBCF-HTB132 (MDA-MB-468) .............................................................................................................3 3. REAGENTS ...........................................................................................................................................5 A. PREPARATION OF COMPLETE GROWTH MEDIUM......................................................................................6 4. THAWING AND PROPAGATION OF CELLS ......................................................................................6 A. THAWING CELLS ...................................................................................................................................6 B. PROPAGATING CELLS ...........................................................................................................................7 C. SUBCULTURING CELLS ..........................................................................................................................8 5. HARVESTING OF CELLS FOR CRYOPRESERVATION ....................................................................9 6. CRYOPRESERVATION OF CELLS .................................................................................................. 11 A. CRYOPRESERVATION USING A RATE-CONTROLLED PROGRAMMABLE FREEZER ...................................... 11 i. Using the Cryomed ..................................................................................................................... 11 B.

  8. Cherry Featured in NCIís Spotlight on Scientists Video Series | Poster

    Cancer.gov

    James Cherry, Ph.D., learned at an early age that education is crucial to success. He credits his mentors, some of whom include his grandmother, Shepherd University professor Burton Lidgerding, Ph.D., David Munroe, Ph.D., Frederick National Lab, and Robert J. Hohman, Ph.D., National Institute of Allergy and Infectious Diseases, for guiding him to the career he has today. Cherry, scientific program director, Office of Scientific Operations (OSO), NCI at Frederick, is one of the scientists featured in†NCIís Spotlight on Scientists†video series.

  9. Connecting Genomic Alterations to Cancer Biology with Proteomics: The NCI Clinical Proteomic Tumor Analysis Consortium

    SciTech Connect

    Ellis, Matthew; Gillette, Michael; Carr, Steven A.; Paulovich, Amanda G.; Smith, Richard D.; Rodland, Karin D.; Townsend, Reid; Kinsinger, Christopher; Mesri, Mehdi; Rodriguez, Henry; Liebler, Daniel

    2013-10-03

    The National Cancer Institute (NCI) Clinical Proteomic Tumor Analysis Consortium is applying the latest generation of proteomic technologies to genomically annotated tumors from The Cancer Genome Atlas (TCGA) program, a joint initiative of the NCI and the National Human Genome Research Institute. By providing a fully integrated accounting of DNA, RNA, and protein abnormalities in individual tumors, these datasets will illuminate the complex relationship between genomic abnormalities and cancer phenotypes, thus producing biologic insights as well as a wave of novel candidate biomarkers and therapeutic targets amenable to verifi cation using targeted mass spectrometry methods.

  10. Variant anatomy of internal jugular vein branching

    PubMed Central

    Deepak, Chris A.; Sarvadnya, Jagadish J.; Sabitha, K. S.

    2015-01-01

    The knowledge of both normal and abnormal anatomy of the veins of the neck is important for clinicians performing catheterization and surgeons operating in the region of the neck. The presence of such anomalous communications may also be important for radiologists performing angiographic and sonographic studies. This study presents three cases of variant anatomy in posterior branching and abnormal branching of internal jugular vein found during our routine neck dissection.

  11. Medical student participation in surface anatomy classes.

    PubMed

    Aggarwal, R; Brough, H; Ellis, H

    2006-10-01

    Surface anatomy is an integral part of medical education and enables medical students to learn skills for future medical practice. In the past decade, there has been a decline in the teaching of anatomy in the medical curriculum, and this study seeks to assess the attitudes of medical students to participation in surface anatomy classes. Consequently, all first year medical students at the Guy's, King's and St Thomas's Medical School, London, were asked to fill in an anonymous questionnaire at the end of their last surface anatomy session of the year. A total of 290 medical students completed the questionnaires, resulting in an 81.6% response rate. The students had a mean age of 19.6 years (range 18-32) and 104 (35.9%) of them were male. Seventy-six students (26.2%) were subjects in surface anatomy tutorials (60.5% male). Students generally volunteered because no one else did. Of the volunteers, 38.2% would rather not have been subjects, because of embarrassment, inability to make notes, or to see clearly the material being taught. Female medical students from ethnic minority groups were especially reluctant to volunteer to be subjects. Single-sex classes improved the volunteer rate to some extent, but not dramatically. Students appreciate the importance of surface anatomy to cadaveric study and to future clinical practice. Computer models, lectures, and videos are complementary but cannot be a substitute for peer group models, artists' models being the only alternative. PMID:16302232

  12. Normal distal pulmonary vein anatomy

    PubMed Central

    Klimek-Piotrowska, Wies?awa; Pi?tek, Katarzyna; Koziej, Mateusz; Ho?da, Jakub

    2016-01-01

    Background. It is well known that the pulmonary veins (PVs), especially their myocardial sleeves play a critical role in the initiation and maintenance of atrial fibrillation. Understanding the PV anatomy is crucial for the safety and efficacy of all procedures performed on PVs. The aim of this study was to present normal distal PV anatomy and to create a juxtaposition of all PV ostium variants. Methods. A total of 130 randomly selected autopsied adult human hearts (Caucasian) were examined. The number of PVs ostia was evaluated and their diameter was measured. The ostium-to-last-tributary distance and macroscopic presence of myocardial sleeves were also evaluated. Results. Five hundred forty-one PV ostia were identified. Four classical PV ostia patterns (two left and two right PVs) were observed in 70.8% of all cases. The most common variant was the classical pattern with additional middle right PV (19.2%), followed by the common ostium for the left superior and the inferior PVs (4.44%). Mean diameters of PV ostia (for the classical pattern) were: left superior = 13.8 Ī 2.9 mm; left inferior = 13.3 Ī 3.4 mm; right superior = 14.3 Ī 2.9 mm; right inferior = 13.7 Ī 3.3 mm. When present, the additional middle right PV ostium had the smallest PV ostium diameter in the heart (8.2 Ī 4.1 mm). The mean ostium-to-last-tributary (closest to the atrium) distances were: left superior = 15.1 Ī 4.6 mm; left inferior = 13.5 Ī 4.0 mm; right superior = 11.8 Ī 4.0 mm; right inferior = 11.0 Ī 3.7 mm. There were no statistically significant differences between sexes in ostia diameters and ostium-to-last-tributary distances. Conclusion. Only 71% of the cases have four standard pulmonary veins. The middle right pulmonary vein is present in almost 20% of patients. Presented data can provide useful information for the clinicians during interventional procedures or radiologic examinations of PVs. PMID:26793429

  13. Normal distal pulmonary vein anatomy.

    PubMed

    Klimek-Piotrowska, Wies?awa; Ho?da, Mateusz K; Pi?tek, Katarzyna; Koziej, Mateusz; Ho?da, Jakub

    2016-01-01

    Background. It is well known that the pulmonary veins (PVs), especially their myocardial sleeves play a critical role in the initiation and maintenance of atrial fibrillation. Understanding the PV anatomy is crucial for the safety and efficacy of all procedures performed on PVs. The aim of this study was to present normal distal PV anatomy and to create a juxtaposition of all PV ostium variants. Methods. A total of 130 randomly selected autopsied adult human hearts (Caucasian) were examined. The number of PVs ostia was evaluated and their diameter was measured. The ostium-to-last-tributary distance and macroscopic presence of myocardial sleeves were also evaluated. Results. Five hundred forty-one PV ostia were identified. Four classical PV ostia patterns (two left and two right PVs) were observed in 70.8% of all cases. The most common variant was the classical pattern with additional middle right PV (19.2%), followed by the common ostium for the left superior and the inferior PVs (4.44%). Mean diameters of PV ostia (for the classical pattern) were: left superior = 13.8 Ī 2.9 mm; left inferior = 13.3 Ī 3.4 mm; right superior = 14.3 Ī 2.9 mm; right inferior = 13.7 Ī 3.3 mm. When present, the additional middle right PV ostium had the smallest PV ostium diameter in the heart (8.2 Ī 4.1 mm). The mean ostium-to-last-tributary (closest to the atrium) distances were: left superior = 15.1 Ī 4.6 mm; left inferior = 13.5 Ī 4.0 mm; right superior = 11.8 Ī 4.0 mm; right inferior = 11.0 Ī 3.7 mm. There were no statistically significant differences between sexes in ostia diameters and ostium-to-last-tributary distances. Conclusion. Only 71% of the cases have four standard pulmonary veins. The middle right pulmonary vein is present in almost 20% of patients. Presented data can provide useful information for the clinicians during interventional procedures or radiologic examinations of PVs. PMID:26793429

  14. Building a Low-Cost Gross Anatomy Laboratory: A Big Step for a Small University

    ERIC Educational Resources Information Center

    Goldman, Evan

    2010-01-01

    This article illustrates details of the planning, building, and improvement phases of a cost-efficient, full-dissection gross anatomy laboratory on a campus of an historically design-centric university. Special considerations were given throughout the project to the nature of hosting cadavers in a building shared amongst all undergraduate majors.Ö

  15. Building a Low-Cost Gross Anatomy Laboratory: A Big Step for a Small University

    ERIC Educational Resources Information Center

    Goldman, Evan

    2010-01-01

    This article illustrates details of the planning, building, and improvement phases of a cost-efficient, full-dissection gross anatomy laboratory on a campus of an historically design-centric university. Special considerations were given throughout the project to the nature of hosting cadavers in a building shared amongst all undergraduate majors.…

  16. AACR 2014: NCI/NIH-Sponsored Session: Large-Scale Genomics Data for the Research Community through the NCI Center for Cancer Genomics

    Cancer.gov

    The NCIís Center for Cancer Genomics (CCG), which includes the Office of Cancer Genomics and The Cancer Genome Atlas Program Office, provides the research community access to large-scale molecular characterization data, which is largely sequence-based. CCG programs aim to improve patient outcome through identification of valid molecular targets and associated molecular markers (prognostic or diagnostic), in and across diseases investigated, which should ultimately lead to the rapid development of novel, more effective therapies.

  17. Molecular Anatomy of Palate Development

    PubMed Central

    Potter, Andrew S.; Potter, S. Steven

    2015-01-01

    The NIH FACEBASE consortium was established in part to create a central resource for craniofacial researchers. One purpose is to provide a molecular anatomy of craniofacial development. To this end we have used a combination of laser capture microdissection and RNA-Seq to define the gene expression programs driving development of the murine palate. We focused on the E14.5 palate, soon after medial fusion of the two palatal shelves. The palate was divided into multiple compartments, including both medial and lateral, as well as oral and nasal, for both the anterior and posterior domains. A total of 25 RNA-Seq datasets were generated. The results provide a comprehensive view of the region specific expression of all transcription factors, growth factors and receptors. Paracrine interactions can be inferred from flanking compartment growth factor/receptor expression patterns. The results are validated primarily through very high concordance with extensive previously published gene expression data for the developing palate. In addition selected immunostain validations were carried out. In conclusion, this report provides an RNA-Seq based atlas of gene expression patterns driving palate development at microanatomic resolution. This FACEBASE resource is designed to promote discovery by the craniofacial research community. PMID:26168040

  18. Auditory pathways: anatomy and physiology.

    PubMed

    Pickles, James O

    2015-01-01

    This chapter outlines the anatomy and physiology of the auditory pathways. After a brief analysis of the external, middle ears, and cochlea, the responses of auditory nerve fibers are described. The central nervous system is analyzed in more detail. A scheme is provided to help understand the complex and multiple auditory pathways running through the brainstem. The multiple pathways are based on the need to preserve accurate timing while extracting complex spectral patterns in the auditory input. The auditory nerve fibers branch to give two pathways, a ventral sound-localizing stream, and a dorsal mainly pattern recognition stream, which innervate the different divisions of the cochlear nucleus. The outputs of the two streams, with their two types of analysis, are progressively combined in the inferior colliculus and onwards, to produce the representation of what can be called the "auditory objects" in the external world. The progressive extraction of critical features in the auditory stimulus in the different levels of the central auditory system, from cochlear nucleus to auditory cortex, is described. In addition, the auditory centrifugal system, running from cortex in multiple stages to the organ of Corti of the cochlea, is described. PMID:25726260

  19. Brain anatomy in Diplura (Hexapoda)

    PubMed Central

    2012-01-01

    Background In the past decade neuroanatomy has proved to be a valuable source of character systems that provide insights into arthropod relationships. Since the most detailed description of dipluran brain anatomy dates back to Hanström (1940) we re-investigated the brains of Campodea augens and Catajapyx aquilonaris with modern neuroanatomical techniques. The analyses are based on antibody staining and 3D reconstruction of the major neuropils and tracts from semi-thin section series. Results Remarkable features of the investigated dipluran brains are a large central body, which is organized in nine columns and three layers, and well developed mushroom bodies with calyces receiving input from spheroidal olfactory glomeruli in the deutocerebrum. Antibody staining against a catalytic subunit of protein kinase A (DC0) was used to further characterize the mushroom bodies. The japygid Catajapyx aquilonaris possesses mushroom bodies which are connected across the midline, a unique condition within hexapods. Conclusions Mushroom body and central body structure shows a high correspondence between japygids and campodeids. Some unique features indicate that neuroanatomy further supports the monophyly of Diplura. In a broader phylogenetic context, however, the polarization of brain characters becomes ambiguous. The mushroom bodies and the central body of Diplura in several aspects resemble those of Dicondylia, suggesting homology. In contrast, Archaeognatha completely lack mushroom bodies and exhibit a central body organization reminiscent of certain malacostracan crustaceans. Several hypotheses of brain evolution at the base of the hexapod tree are discussed. PMID:23050723

  20. The human anatomy teacher-scholar: Meeting the expectations of educational outcomes research, course content innovation, and textbook innovation for educational scholarship

    NASA Astrophysics Data System (ADS)

    Eckel, Christine Marie

    A human anatomy teacher-scholar is a scholar whose area of expertise includes content knowledge of the anatomical sciences (gross anatomy, histology, embryology, and/or neuroanatomy) and whose research interests and focus are centered in medical educational outcomes. The projects described in this dissertation represent endeavors I engaged in to become a human anatomy teacher-scholar. These projects included: (1) prospectively testing a hypothesis, and performing outcomes assessment in a field for which little data (theory) exist (dissection guide educational research project), (2) creating innovative course content that bridged disciplines (cadaver autopsy project), and (3) composing original teaching material for a specific audience (human anatomy laboratory manual). The training of a human anatomy teacher-scholar emphasizes knowledge acquisition in both the basic sciences (particularly gross anatomy) and in educational outcomes research methodology and theory. Therefore, human anatomy teacher-scholars are positioned to create innovative course content and materials and assess the innovations to guide future efforts. These are important skills for faculty members involved in the education of medical students in the U.S. as the medical education system in the U.S. continues to evolve.

  1. About NExT | NCI Experimental Therapeutics (NExT)

    Cancer.gov

    Skip to Content Search this site ABOUT NExT NCINExTInfo@mail.nih.gov Overview Mission Contacts Last Updated: 09/26/14 Screening/Hit-to-Lead Stage NExT Projects Applicant Institute Project Dang, Chi University of Pennsylvania Development of FX11, a

  2. About NExT | NCI Experimental Therapeutics (NExT)

    Cancer.gov

    Skip to Content Search this site ABOUT NExT NCINExTInfo@mail.nih.gov Overview Mission Contacts Last Updated: 09/25/14 Preclinical Evaluation Stage NExT Projects Applicant Institute Project Cassady, Kevin University of Alabama at Birmingham Production

  3. NCI at Frederick Employees Receive Awards at the Spring Research Festival | Poster

    Cancer.gov

    NCI and Frederick National Laboratory staff members were among those honored at the Spring Research Festival Awards Ceremony on May 28. The ceremony was the culmination of the festival, which was sponsored by the National Interagency Confederation for Biological Research (NICBR), May 4‚Äď7. Maj. Gen. Brian Lein, commanding general, U.S. Army Medical Research and Materiel Command (USAMRMC), presented the awards.

  4. Applications ó CBIIT: Welcome to the NCI Center for Biomedical Informatics and Information Technology

    Cancer.gov

    As part of the CBIIT Open-Development Initiative (ODI), the NCIP is migrating application source code, and in some instances associated data or documentation, into the GitHub open-development environment. NCI's goal in taking this step is to lower the barriers to community participation, stimulate innovation, and accelerate the ongoing development of these assets.

  5. Publicaciůn de Propuesta Presupuestaria del NCI para el AŮo Fiscal 2017

    Cancer.gov

    Ayer, tuve el honor de presentar al Presidente Barack Obama el Plan Anual del NCI y Propuesta Presupuestaria para el AŮo Fiscal 2017. Creo que la ďPropuesta PresupuestariaĒ, como se conoce ahora, es especialmente importante este aŮo para la investigaciůn oncolůgica por dos razones.

  6. Aspectos generales de la Red Nacional de Estudios ClŪnicos del NCI

    Cancer.gov

    ReseŮa general sobre la estructura organizativa de la Red Nacional de Estudios ClŪnicos del NCI, asŪ como un resumen de los cambios que se estŠn llevando a cabo y una sinopsis de cůmo estos cambios se basan en el ťxito del programa de Grupos Cooperativos.

  7. NCI announces ten winning teams of entrepreneurs for its Breast Cancer Startup Challenge

    Cancer.gov

    The winners of a world-wide competition to bring emerging breast cancer research technologies to market faster were announced yesterday by the Avon Foundation for Women, in partnership with the National Cancer Institute (NCI) and the Center for Advancing Innovation (CAI).

  8. Se lanza Red Nacional de Estudios Clínicos del NCI

    Cancer.gov

    El Instituto Nacional del C√°ncer (NCI) puso en marcha una nueva red de investigaci√≥n de estudios cl√≠nicos con el objetivo de mejorar el tratamiento de m√°s de 1,6 millones de estadounidenses que reciben un diagn√≥stico de c√°ncer cada a√Īo.

  9. Centro de Contacto del NCIóServicio de Informaciůn sobre el CŠncer

    Cancer.gov

    El Instituto Nacional del CŠncer (NCI) ofrece informaciůn actualizada, precisa, confiable y fŠcil de entender sobre diferentes de temas de cŠncer. Los especialistas en informaciůn le pueden ayudar en el telťfono 1-800-422-6237 (1-800-4-CANCER).

  10. NCI's Annual Report on Complementary and Alternative Medicine(CAM) Fiscal Year 2006

    Cancer.gov

    Twin Cities Public Television. The screening was held for staff members from the National Center for Complementary and Alternative Medicine (NCCAM), the National Institute of Mental Health (NIMH), the Office of Behavioral and Social Sciences Research, and NCI. Dr. Margaret Chesney of NCCAM and Dr. Esther Sternberg of NIMH, both featured in the documentary, answered questions concerning the featured research studies and concepts.

  11. 78 FR 19496 - Submission for OMB Review; 30-day Comment Request; The National Cancer Institute (NCI...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ... National Cancer Institute (NCI) SmokefreeTXT Program Evaluation SUMMARY: Under the provisions of Section..., contact Erik Augustson, Ph.D., MPH, Behavioral Scientist/Health Science Administrator, Division of Cancer Control and Population Sciences, 6130 Executive Blvd., EPN-4034, Bethesda, MD 20892-7337 or call...

  12. NCI Community Cancer Centers Program - Related Programs - The Cancer Genome Atlas

    Cancer.gov

    The Cancer Genome Atlas (TCGA) is a large-scale collaborative effort by NCI and the National Human Genome Research Institute (NHGRI) to systematically characterize the genomic changes that occur in cancer through the application of genome analysis technologies, including large-scale genome sequencing.

  13. 75 FR 70268 - Submission for OMB Review; Comment Request; NIH NCI Central Institutional Review Board (CIRB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-17

    ... Federal Register on August 16, 2010 (75 FR 49938) and allowed 60-days for public comment. No public... (Attachment 2K). Participants Facilitated Review (FR) 1,450 1 10/60 (.17 hour) 242 Acceptance Form (Attachment... Paperwork Reduction Act of 1995, the National Cancer Institute (NCI), the National Institutes of Health...

  14. Treatment of Prostate Cancer using Anti-androgen Small Molecules | NCI Technology Transfer Center | TTC

    Cancer.gov

    The National Cancer Institute seeks parties interested in collaborative research to co-develop and commercialize a new class of small molecules for the treatment of prostate cancer. General information on co-development research collaborations, can be found on our web site (http://ttc.nci.nih.gov/forms).

  15. (Update) HIV Conference to Be Held on February 25 at NCI at Frederick | Poster

    Cancer.gov

    By Anne Arthur, Guest Writer The HIV Drug Resistance Program (HIV DRP), Center for Cancer Research (CCR), will hold a conference on ‚ÄúHost Factors and Cofactors in HIV Infection‚ÄĚ at the National Cancer Institute (NCI) campus in Frederick, Md., on Feb. 25, from 1:00 to 5:35 p.m.

  16. HIV Conference to Be Held on October 21 at NCI at Frederick | Poster

    Cancer.gov

    By Anne Arthur, Guest Writer The HIV Drug Resistance Program Conference on ‚ÄúVirus Structure: Putting the Pieces Together‚ÄĚ will be held at NCI at Frederick on October 21, 2014, from 1:00 to 5:45 p.m. in the Conference Center auditorium, Building 549.

  17. 75 FR 4827 - Submission for OMB Review; Comment Request Clinical Trials Reporting Program (CTRP) Database (NCI)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-29

    ... HUMAN SERVICES National Institutes of Health Submission for OMB Review; Comment Request Clinical Trials... purpose and safety of clinical trials conducted outside of the United States. An e-mail response was sent... of the NCI's clinical trials portfolio, which is global in nature. The response further stated...

  18. NCI: SBIR & STTR - Find Funding - Contracts - 289 Physical Property-Based High-Throughput Protein Sequencing

    Cancer.gov

    Therefore, the NCI is interested in proposals that focus on the development of novel, fast, reliable and economical protein sequencing alternative technologies that rely on approaches other than tandem mass spectrometry involving theoretical spectral sequences. The purpose is to stimulate the community to develop new HT-protein sequencing technologies based solely on physical, chemical, or biological properties.

  19. Revisiting the Anatomy of the Living Heart.

    PubMed

    Mori, Shumpei; Spicer, Diane E; Anderson, Robert H

    2015-12-25

    An understanding of the complexity of cardiac anatomy is required by all who seek, in the setting of cardiac disease, to interpret the images confronting them. Although the mysteries of cardiac structure have been extensively addressed, significant gaps continue to exist between the descriptions provided by morphologists and by those working in the clinical setting. In part, this reflects the limitations in providing 3D visualization of such a complicated organ. Current 3D imaging technology now permits visualization of the cardiac components using datasets obtained in the living individual. These advances, furthermore, demonstrate the anatomy in the setting of the heart as imaged within the thorax. It has been failure to describe the heart as it lies within the thorax that remains a major deficiency of many morphologists relying on the dissecting room to provide the gold standard. Describing the heart in attitudinally appropriate fashion, a basic rule of clinical anatomy, creates the necessary bridges between anatomists and clinicians. The rapid progression of cardiac interventional techniques, furthermore, emphasizes the need to revisit cardiac anatomy using a multidisciplinary approach. In this review, therefore, we illustrate the advantages of an attitudinally correct approach to cardiac anatomy. We then focus on the morphology of the arterial roots, revealing the accuracy that can now be achieved by clinicians using datasets obtained during life. (Circ J 2016; 80: 24-33). PMID:26673171

  20. Exploring relationships between personality and anatomy performance.

    PubMed

    Finn, Gabrielle M; Walker, Simon J; Carter, Madeline; Cox, David R; Hewitson, Ruth; Smith, Claire F

    2015-01-01

    There is increasing recognition in medicine of the importance of noncognitive factors, including personality, for performance, and for good medical practice. The personality domain of conscientiousness is a well-established predictor of performance in workplace and academic settings. This study investigates the relationships between the "Big Five" personality domains, the facets of conscientiousness and performance in a practical anatomy examination. First- and second-year undergraduate medical students (n‚ÄČ=‚ÄČ85) completed a paper-based questionnaire, which included a 50-item measure of the Big Five personality domains (neuroticism, extraversion, openness to experience, agreeableness, and conscientiousness) and a 60-item measure of the six conscientiousness facets (orderliness, dutifulness, achievement-striving, self-discipline, self-efficacy, and cautiousness) from the International Personality Item Pool (IPIP). In addition, routinely-collected academic performance scores from the end of semester anatomy practical examinations (spotters) were obtained. Anatomy examination performance correlated moderately with conscientiousness (r‚ÄČ=‚ÄČ0.24, P‚ÄČ=‚ÄČ0.03). Of the six facets of conscientiousness, a positive relationship was observed between anatomy examination performance and achievement striving (r‚ÄČ=‚ÄČ0.22, P‚ÄČ=‚ÄČ0.05). In conclusion, this study found that performance in an anatomy examination was related to higher levels of conscientiousness and, more specifically, to higher levels of achievement striving. The results have implications for selection and assessment in medicine. PMID:25716097

  1. The surgical anatomy of the perineum.

    PubMed

    Mahadevan, V; Chandak, P

    2013-03-01

    The anatomy of the perineum and pelvis is complex. Those outside the specialist fields of colorectal surgery, urology and gynaecological surgery often have a less-than-complete understanding of the anatomical details of this region. The recent increase in complicated pelvic and perineal injuries caused by the detonation of Improvised Explosive Devices has brought into sharp focus, the importance of this area of surgical anatomy. The following article describes, in a systematic and detailed manner, the anatomy of the urogenital and anal regions of the perineum. The terminology in relation to the fascial layers and structures encountered in the perineum is elucidated. In addition, the surgical anatomy of the scrotum and its contents and the ligamentous support of the penis are described, with clear illustrations throughout. It is intended that this article will go some way towards clarifying the anatomy underlying the surgical management of complex perineal/pelvic injuries, and benefit both the specialist and non-specialist military surgeon. PMID:23631319

  2. Screening Services Ė NCI-60 DTP Human Tumor Cell Line Screen

    Cancer.gov

    The In Vitro Cell Line Screening Project (IVCLSP) is a dedicated service providing direct support to the DTP anticancer drug discovery program. The in vitro cell line screen was implemented in fully operational form in April of 1990. It required approximately five years (1985 - 1990) to develop, and persistence in the effort reflected dissatisfaction with the performance of prior in vivo primary screens. This project is designed to screen up to 3,000 compounds per year for potential anticancer activity.

  3. Smooth extrapolation of unknown anatomy via statistical shape models

    NASA Astrophysics Data System (ADS)

    Grupp, R. B.; Chiang, H.; Otake, Y.; Murphy, R. J.; Gordon, C. R.; Armand, M.; Taylor, R. H.

    2015-03-01

    Several methods to perform extrapolation of unknown anatomy were evaluated. The primary application is to enhance surgical procedures that may use partial medical images or medical images of incomplete anatomy. Le Fort-based, face-jaw-teeth transplant is one such procedure. From CT data of 36 skulls and 21 mandibles separate Statistical Shape Models of the anatomical surfaces were created. Using the Statistical Shape Models, incomplete surfaces were projected to obtain complete surface estimates. The surface estimates exhibit non-zero error in regions where the true surface is known; it is desirable to keep the true surface and seamlessly merge the estimated unknown surface. Existing extrapolation techniques produce non-smooth transitions from the true surface to the estimated surface, resulting in additional error and a less aesthetically pleasing result. The three extrapolation techniques evaluated were: copying and pasting of the surface estimate (non-smooth baseline), a feathering between the patient surface and surface estimate, and an estimate generated via a Thin Plate Spline trained from displacements between the surface estimate and corresponding vertices of the known patient surface. Feathering and Thin Plate Spline approaches both yielded smooth transitions. However, feathering corrupted known vertex values. Leave-one-out analyses were conducted, with 5% to 50% of known anatomy removed from the left-out patient and estimated via the proposed approaches. The Thin Plate Spline approach yielded smaller errors than the other two approaches, with an average vertex error improvement of 1.46 mm and 1.38 mm for the skull and mandible respectively, over the baseline approach.

  4. A powerful way of teaching anatomy.

    PubMed

    Mavridis, Ioannis N

    2013-05-01

    I read the article entitled "A plea for the use of drawing in human anatomy teaching", by Clavert et al. with great interest. I was glad to read that, in France, anatomy is initially taught by building each structure or region on a blackboard with colored chalk. I find this method quite efficient for this purpose. I believe that drawing is a powerful way of teaching anatomy and therefore the blackboard deserves its rightful place beside other 'high-tech' media. I agree with the authors that the blackboard and the chalk constitute wonderful and powerful educational media, and that appropriate simplification and transposing (of anatomical information) in daily practice are necessary for a sufficient educational result. Among other 'modern' media, movies of surgical procedures could easily attract the students' attention. PMID:23180394

  5. Greek anatomist herophilus: the father of anatomy.

    PubMed

    Bay, Noel Si-Yang; Bay, Boon-Huat

    2010-12-01

    One of the most stirring controversies in the history of Anatomy is that Herophilus, an ancient Greek anatomist and his younger contemporary, Erasistratus, were accused of performing vivisections of living humans. However, this does not detract from the fact that Herophilus has made phenomenal anatomical observations of the human body which have contributed significantly towards the understanding of the brain, eye, liver, reproductive organs and nervous system. It is notable that he was the first person to perform systematic dissection of the human body and is widely acknowledged as the Father of Anatomy. He has been hailed as one of the greatest anatomists that ever lived, rivaled only by Andreas Vesalius who is regarded as the founder of modern human anatomy. PMID:21267401

  6. Greek anatomist herophilus: the father of anatomy

    PubMed Central

    Bay, Noel Si-Yang

    2010-01-01

    One of the most stirring controversies in the history of Anatomy is that Herophilus, an ancient Greek anatomist and his younger contemporary, Erasistratus, were accused of performing vivisections of living humans. However, this does not detract from the fact that Herophilus has made phenomenal anatomical observations of the human body which have contributed significantly towards the understanding of the brain, eye, liver, reproductive organs and nervous system. It is notable that he was the first person to perform systematic dissection of the human body and is widely acknowledged as the Father of Anatomy. He has been hailed as one of the greatest anatomists that ever lived, rivaled only by Andreas Vesalius who is regarded as the founder of modern human anatomy. PMID:21267401

  7. Anatomy of a Busted Comet

    NASA Technical Reports Server (NTRS)

    2008-01-01

    [figure removed for brevity, see original site] Poster Version (Figure 1)

    NASA's Spitzer Space Telescope captured the picture on the left of comet Holmes in March 2008, five months after the comet suddenly erupted and brightened a millionfold overnight. The contrast of the picture has been enhanced on the right to show the anatomy of the comet.

    Every six years, comet 17P/Holmes speeds away from Jupiter and heads inward toward the sun, traveling the same route typically without incident. However, twice in the last 116 years, in November 1892 and October 2007, comet Holmes mysteriously exploded as it approached the asteroid belt. Astronomers still do not know the cause of these eruptions.

    Spitzer's infrared picture at left hand side of figure 1, reveals fine dust particles that make up the outer shell, or coma, of the comet. The nucleus of the comet is within the bright whitish spot in the center, while the yellow area shows solid particles that were blown from the comet in the explosion. The comet is headed away from the sun, which lies beyond the right-hand side of figure 1.

    The contrast-enhanced picture on the right shows the comet's outer shell, and strange filaments, or streamers, of dust. The streamers and shell are a yet another mystery surrounding comet Holmes. Scientists had initially suspected that the streamers were small dust particles ejected from fragments of the nucleus, or from hyerpactive jets on the nucleus, during the October 2007 explosion. If so, both the streamers and the shell should have shifted their orientation as the comet followed its orbit around the sun. Radiation pressure from the sun should have swept the material back and away from it. But pictures of comet Holmes taken by Spitzer over time show the streamers and shell in the same configuration, and not pointing away from the sun. The observations have left astronomers stumped.

    The horizontal line seen in the contrast-enhanced picture is a trail of debris that travels along with the comet in its orbit.

    The Spitzer picture was taken with the spacecraft's multiband imaging photometer at an infrared wavelength of 24 microns.

  8. Anatomy of an entry vehicle experiment

    NASA Technical Reports Server (NTRS)

    Eide, D. G.; Wurster, K. E.; Helms, V. T.; Ashby, G. C.

    1981-01-01

    The anatomy and evolution of a simple small-scale unmanned entry vehicle is described that is delivered to orbit by the shuttle and entered into the atmosphere from orbit to acquire flight data to improve our knowledge of boundary-layer behavior and evaluate advanced thermal protection systems. The anatomy of the experiment includes the justification for the experiments, instrumentation, configuration, material, and operational needs, and the translation of these needs into a configuration, weight statement, aerodynamics, program cost, and trajectory. Candidates for new instrumentation development are also identified for nonintrusive measurements of the boundary-layer properties.

  9. Functional Anatomy of the Outflow Facilities.

    PubMed

    Pizzirani, Stefano; Gong, Haiyan

    2015-11-01

    In order to understand the pathophysiology, select optimal therapeutic options for patients and provide clients with honest expectations for cases of canine glaucoma, clinicians should be familiar with a rational understanding of the functional anatomy of the ocular structures involved in this group of diseases. The topographical extension and the structural and humoral complexity of the regions involved with the production and the outflow of aqueous humor undergo numerous changes with aging and disease. Therefore, the anatomy relative to the fluid dynamics of aqueous has become a pivotal yet flexible concept to interpret the different phenotypes of glaucoma. PMID:26337760

  10. Surgical anatomy of the tracheobronchial tree

    PubMed Central

    Drevet, Gabrielle; Conti, Massimo

    2016-01-01

    Airway surgery is often indicated in the management of benign or malignant pathological processes of the tracheobronchial tree. The surgeon undertaking this type of work has, however, the responsibility of understanding the particular anatomy applicable to these structures and procedures as well as be able to correlate imaging, intraoperative findings and anatomy. These are important considerations if one wants to reduce operative morbidity and improve potential for better long-term results. This paper reviews the most important anatomic features of the tracheobronchial tree putting emphasis on those features that are important to surgeons performing surgical procedures on those organs. PMID:26981262

  11. Management of Elbow Trauma: Anatomy and Exposures.

    PubMed

    Barco, Raul; AntuŮa, Samuel A

    2015-11-01

    The elbow is a complex joint from the anatomic and biomechanical point of view. A thorough understanding of elbow anatomy greatly aids the surgeon in dealing with elbow trauma. The close vicinity of neurovascular structures should always be kept in mind when selecting a surgical approach. Any approach to the elbow needs to be safe and versatile. Knowledge of the attachment and orientation of elbow ligaments reduces the risk of inadvertent intraoperative injury and/or postoperative instability. Surgeons dealing with elbow trauma should have a good working understanding of elbow anatomy and the available approaches to effectively and efficiently conduct the surgical procedure to maximize outcomes and minimize complications. PMID:26498541

  12. Project TAPS. Progress Report Number 2.

    ERIC Educational Resources Information Center

    Desch, S. H.; Stolurow, L. M.

    TRIGEM, a computer-assisted instruction (CAI) course developed as a part of Project TAPS (Teaching Anatomy with Programed Schematics) is designed to teach the anatomy of the maxillary division of the trigeminal nerve. This course is currently operational on the Harvard CAI System which uses an IBM S 360/Model 65 as the central processor, eitherÖ

  13. Perceptions of Anatomy Education--A Student's View

    ERIC Educational Resources Information Center

    Joslin, Sarah

    2008-01-01

    Changes in anatomy education over the last two decades have, in large part, led to less emphasis on gross anatomy in the medical curriculum. This has led many to question whether streamlined anatomy courses truly provide adequate preparation for medical practice. Rather than wondering about the effects of these changes, we should be actively…

  14. Learning of Cross-Sectional Anatomy Using Clay Models

    ERIC Educational Resources Information Center

    Oh, Chang-Seok; Kim, Ji-Young; Choe, Yeon Hyeon

    2009-01-01

    We incorporated clay modeling into gross anatomy and neuro-anatomy courses to help students understand cross-sectional anatomy. By making clay models, cutting them and comparing cut surfaces to CT and MR images, students learned how cross-sectional two-dimensional images were created from three-dimensional structure of human organs. Most students…

  15. Teaching Anatomy and Physiology Using Computer-Based, Stereoscopic Images

    ERIC Educational Resources Information Center

    Perry, Jamie; Kuehn, David; Langlois, Rick

    2007-01-01

    Learning real three-dimensional (3D) anatomy for the first time can be challenging. Two-dimensional drawings and plastic models tend to over-simplify the complexity of anatomy. The approach described uses stereoscopy to create 3D images of the process of cadaver dissection and to demonstrate the underlying anatomy related to the speech mechanisms.…

  16. Guidelines for Standard Photography in Gross and Clinical Anatomy

    ERIC Educational Resources Information Center

    Barut, Cagatay; Ertilav, Hakan

    2011-01-01

    Photography has a widespread usage in medicine and anatomy. In this review, authors focused on the usage of photography in gross and clinical anatomy. Photography in gross and clinical anatomy is not only essential for accurate documentation of morphological findings but also important in sharing knowledge and experience. Photographs of cadavers…

  17. Guidelines for Standard Photography in Gross and Clinical Anatomy

    ERIC Educational Resources Information Center

    Barut, Cagatay; Ertilav, Hakan

    2011-01-01

    Photography has a widespread usage in medicine and anatomy. In this review, authors focused on the usage of photography in gross and clinical anatomy. Photography in gross and clinical anatomy is not only essential for accurate documentation of morphological findings but also important in sharing knowledge and experience. Photographs of cadaversÖ

  18. Learning of Cross-Sectional Anatomy Using Clay Models

    ERIC Educational Resources Information Center

    Oh, Chang-Seok; Kim, Ji-Young; Choe, Yeon Hyeon

    2009-01-01

    We incorporated clay modeling into gross anatomy and neuro-anatomy courses to help students understand cross-sectional anatomy. By making clay models, cutting them and comparing cut surfaces to CT and MR images, students learned how cross-sectional two-dimensional images were created from three-dimensional structure of human organs. Most studentsÖ

  19. Teaching Anatomy and Physiology Using Computer-Based, Stereoscopic Images

    ERIC Educational Resources Information Center

    Perry, Jamie; Kuehn, David; Langlois, Rick

    2007-01-01

    Learning real three-dimensional (3D) anatomy for the first time can be challenging. Two-dimensional drawings and plastic models tend to over-simplify the complexity of anatomy. The approach described uses stereoscopy to create 3D images of the process of cadaver dissection and to demonstrate the underlying anatomy related to the speech mechanisms.Ö

  20. Perceptions of Anatomy Education--A Student's View

    ERIC Educational Resources Information Center

    Joslin, Sarah

    2008-01-01

    Changes in anatomy education over the last two decades have, in large part, led to less emphasis on gross anatomy in the medical curriculum. This has led many to question whether streamlined anatomy courses truly provide adequate preparation for medical practice. Rather than wondering about the effects of these changes, we should be activelyÖ

  1. Properties of Publications on Anatomy in Medical Education Literature

    ERIC Educational Resources Information Center

    Vorstenbosch, Marc; Bolhuis, Sanneke; van Kuppeveld, Sascha; Kooloos, Jan; Laan, Roland

    2011-01-01

    Publications on anatomy in medical education appear to be largely anecdotal. To explore this, we investigated the literature on anatomy in medical education, aiming first to evaluate the contribution of the literature on anatomy in medical education to "best evidence medical education" (BEME) and second to evaluate the development of thisÖ

  2. NCI Center of Excellence in Integrative Cancer Biology and Genomics

    Cancer.gov

    NIH Director's Challenge Award Program Frank Gonzalez, Ph.D. (Laboratory of Metabolism) and fellow NIH collaborators for their work on "Early Biomarkers of Nephropathy in Type 2 Diabetes" Tom Misteli, Ph.D. and fellow NIH collaborators for their project e

  3. Methods for Selection of Cancer Patients and Predicting Efficacy of Combination Therapy | NCI Technology Transfer Center | TTC

    Cancer.gov

    The Lung Cancer Biomarkers Group of the National Cancer Institute (NCI) seeks parties interested in collaborative research to further co-develop methods for selecting cancer patients for combination therapy.

  4. Two-Year Community: Human Anatomy Software Use in Traditional and Online Anatomy Laboratory Classes: Student-Perceived Learning Benefits

    ERIC Educational Resources Information Center

    Kuyatt, Brian L.; Baker, Jason D.

    2014-01-01

    This study evaluates the effectiveness of human anatomy software in face-to-face and online anatomy laboratory classes. Cognitive, affective, and psychomotor perceived learning was measured for students using Pearson Education's Practice Anatomy Laboratory 2.0 software. This study determined that student-perceived learning was significantlyÖ

  5. Two-Year Community: Human Anatomy Software Use in Traditional and Online Anatomy Laboratory Classes: Student-Perceived Learning Benefits

    ERIC Educational Resources Information Center

    Kuyatt, Brian L.; Baker, Jason D.

    2014-01-01

    This study evaluates the effectiveness of human anatomy software in face-to-face and online anatomy laboratory classes. Cognitive, affective, and psychomotor perceived learning was measured for students using Pearson Education's Practice Anatomy Laboratory 2.0 software. This study determined that student-perceived learning was significantly…

  6. Anatomy and physiology of genital organs - women.

    PubMed

    Graziottin, Alessandra; Gambini, Dania

    2015-01-01

    "Anatomy is destiny": Sigmund Freud viewed human anatomy as a necessary, although not a sufficient, condition for understanding the complexity of human sexual function with a solid biologic basis. The aim of the chapter is to describe women's genital anatomy and physiology, focusing on women's sexual function with a clinically oriented vision. Key points include: embryology, stressing that the "female" is the anatomic "default" program, differentiated into "male" only in the presence of androgens at physiologic levels for the gestational age; sex determination and sex differentiation, describing the interplay between anatomic and endocrine factors; the "clitoral-urethral-vaginal" complex, the most recent anatomy reading of the corpora cavernosa pattern in women; the controversial G spot; the role of the pelvic floor muscles in modulating vaginal receptivity and intercourse feelings, with hyperactivity leading to introital dyspareunia and contributing to provoked vestibulodynia and recurrent postcoital cystitis, whilst lesions during delivery reduce vaginal sensations, genital arousability, and orgasm; innervation, vessels, bones, ligaments; and the physiology of women's sexual response. Attention to physiologic aging focuses on "low-grade inflammation," genital and systemic, with its impact on women sexual function, especially after the menopause, if the woman does not or cannot use hormone replacement therapy. PMID:26003238

  7. Computerized Grading of Anatomy Laboratory Practical Examinations

    ERIC Educational Resources Information Center

    Krippendorf, Beth B.; Bolender, David L.; Kolesari, Gary L.

    2008-01-01

    At the Medical College of Wisconsin, a procedure was developed to allow computerized grading and grade reporting of laboratory practical examinations in the Clinical Human Anatomy course. At the start of the course, first year medical students were given four Lists of Structures. On these lists, numbered items were arranged alphabetically; theÖ

  8. A Syllabus for Biol 242--Human Anatomy.

    ERIC Educational Resources Information Center

    Jacob, Willis H.

    This document is the fall and spring semester course syllabus of Biology 242--Human Anatomy at Southern University (Louisiana). Sections include: (1) Descriptive Information; (2) Specification of Course Goals and Objectives; (3) Readings; (4) Description of Instructional Procedures; (5) Course Requirements; (6) Course Schedule; (7) Evaluation of…

  9. Anatomy and Physiology. Revised Teacher Edition.

    ERIC Educational Resources Information Center

    Hartman, Danene; And Others

    This curriculum guide contains 14 units of instruction for a course in anatomy and physiology for surgical technology students. The units cover the following topics: (1) organization of the body; (2) cells, tissues, and membranes; (3) integumentary system; (4) skeletal system; (5) muscular system; (6) nervous system; (7) special sense organs; (8)…

  10. Dental embryology, anatomy, development, and aging.

    PubMed

    Lowder, M Q; Mueller, P O

    1998-08-01

    Equine practitioners should be knowledgeable of dental anatomy and development to enhance their skill of age estimation of horses. The permanent teeth of horses are continually undergoing changes in shape and appearance. These changes may be used to suggest a reasonable age range for a horse. PMID:9742661

  11. Professional Storytelling in Clinical Dental Anatomy Teaching

    ERIC Educational Resources Information Center

    Kieser, Jules; Livingstone, Vicki; Meldrum, Alison

    2008-01-01

    The aim of the present work was to see if storytelling in a clinical dental anatomy course would increase student satisfaction. We enhanced teaching by spontaneous storytelling in problem-based learning, in half of the third-year dentistry class. At the end of the course, we administered an anonymous questionnaire to the students in the class,…

  12. Testing to Enhance Retention in Human Anatomy

    ERIC Educational Resources Information Center

    Logan, Jessica M.; Thompson, Andrew J.; Marshak, David W.

    2011-01-01

    Recent work in cognitive psychology has shown that repeatedly testing one's knowledge is a powerful learning aid and provides substantial benefits for retention of the material. To apply this in a human anatomy course for medical students, 39 fill-in-the-blank quizzes of about 50 questions each, one for each region of the body, and four about the…

  13. Professional Storytelling in Clinical Dental Anatomy Teaching

    ERIC Educational Resources Information Center

    Kieser, Jules; Livingstone, Vicki; Meldrum, Alison

    2008-01-01

    The aim of the present work was to see if storytelling in a clinical dental anatomy course would increase student satisfaction. We enhanced teaching by spontaneous storytelling in problem-based learning, in half of the third-year dentistry class. At the end of the course, we administered an anonymous questionnaire to the students in the class,Ö

  14. Testing to Enhance Retention in Human Anatomy

    ERIC Educational Resources Information Center

    Logan, Jessica M.; Thompson, Andrew J.; Marshak, David W.

    2011-01-01

    Recent work in cognitive psychology has shown that repeatedly testing one's knowledge is a powerful learning aid and provides substantial benefits for retention of the material. To apply this in a human anatomy course for medical students, 39 fill-in-the-blank quizzes of about 50 questions each, one for each region of the body, and four about theÖ

  15. Anatomy and Physiology. Revised Teacher Edition.

    ERIC Educational Resources Information Center

    Hartman, Danene; And Others

    This curriculum guide contains 14 units of instruction for a course in anatomy and physiology for surgical technology students. The units cover the following topics: (1) organization of the body; (2) cells, tissues, and membranes; (3) integumentary system; (4) skeletal system; (5) muscular system; (6) nervous system; (7) special sense organs; (8)Ö

  16. Children's Fantasy Literature: Toward an Anatomy.

    ERIC Educational Resources Information Center

    Gooderham, David

    1995-01-01

    States that finding a critical language in which to speak about children's fantasy texts is not as straightforward as might first appear. Discusses ideas held by T. Todorov and J.R.R. Tolkien. Argues that fantasy is a metaphorical mode, and details an anatomy of children's fantasy. Concludes that children's fantasy can be described as a body ofÖ

  17. Computerized Grading of Anatomy Laboratory Practical Examinations

    ERIC Educational Resources Information Center

    Krippendorf, Beth B.; Bolender, David L.; Kolesari, Gary L.

    2008-01-01

    At the Medical College of Wisconsin, a procedure was developed to allow computerized grading and grade reporting of laboratory practical examinations in the Clinical Human Anatomy course. At the start of the course, first year medical students were given four Lists of Structures. On these lists, numbered items were arranged alphabetically; the…

  18. Anatomy, Medical Education, and Human Ancestral Variation

    ERIC Educational Resources Information Center

    Strkalj, Goran; Spocter, Muhammad A.; Wilkinson, A. Tracey

    2011-01-01

    It is argued in this article that the human body both in health and disease cannot be fully understood without adequately accounting for the different levels of human variation. The article focuses on variation due to ancestry, arguing that the inclusion of information pertaining to ancestry in human anatomy teaching materials and courses shouldÖ

  19. Teaching Cell Anatomy with a Fabric Model

    ERIC Educational Resources Information Center

    Kluka, Michelle

    2005-01-01

    Middle schoolers are often first introduced to detailed cellular anatomy through one-dimensional drawings in basic life science books, fill-in-the blank handouts accompanied by notes from the teacher, or desktop hard-plastic commercial models that resemble giant lollipops. One of the most important, yet difficult, life science concepts for…

  20. Anatomy, Medical Education, and Human Ancestral Variation

    ERIC Educational Resources Information Center

    Strkalj, Goran; Spocter, Muhammad A.; Wilkinson, A. Tracey

    2011-01-01

    It is argued in this article that the human body both in health and disease cannot be fully understood without adequately accounting for the different levels of human variation. The article focuses on variation due to ancestry, arguing that the inclusion of information pertaining to ancestry in human anatomy teaching materials and courses should…

  1. Teaching Cell Anatomy with a Fabric Model

    ERIC Educational Resources Information Center

    Kluka, Michelle

    2005-01-01

    Middle schoolers are often first introduced to detailed cellular anatomy through one-dimensional drawings in basic life science books, fill-in-the blank handouts accompanied by notes from the teacher, or desktop hard-plastic commercial models that resemble giant lollipops. One of the most important, yet difficult, life science concepts forÖ

  2. Fostering Improved Anatomy and Physiology Instructor Pedagogy

    ERIC Educational Resources Information Center

    Mattheis, Allison; Jensen, Murray

    2014-01-01

    Despite widespread calls for reform in undergraduate science, technology, engineering, and mathematics education, effecting lasting change in instructor practice is challenging to achieve. This article describes the results of a 2-yr research study that involved efforts to develop the pedagogical expertise of a group of anatomy and physiologyÖ

  3. NCI-FDA Interagency Oncology Task Force Workshop Provides Guidance for Analytical Validation of Protein-based Multiplex Assays

    Cancer.gov

    An NCI-FDA Interagency Oncology Task Force (IOTF) Molecular Diagnostics Workshop was held on October 30, 2008 in Cambridge, MA, to discuss requirements for analytical validation of protein-based multiplex technologies in the context of its intended use. This workshop developed through NCI's Clinical Proteomic Technologies for Cancer initiative and the FDA focused on technology-specific analytical validation processes to be addressed prior to use in clinical settings.

  4. Identification of two nickel ion-induced genes, NCI16 and PcGST1, in Paramecium caudatum.

    PubMed

    Takenaka, Yasuhiro; Haga, Nobuyuki; Inoue, Ikuo; Nakano, Takanari; Ikeda, Masaaki; Katayama, Shigehiro; Awata, Takuya

    2014-09-01

    Here, we describe the isolation of two nickel-induced genes in Paramecium caudatum, NCI16 and PcGST1, by subtractive hybridization. NCI16 encoded a predicted four-transmembrane domain protein (?16 kDa) of unknown function, and PcGST1 encoded glutathione S-transferase (GST; ?25 kDa) with GST and glutathione peroxidase (GPx) activities. Exposing cells to cobalt chloride also caused the moderate upregulation of NCI16 and PcGST1 mRNAs. Both nickel sulfate and cobalt chloride dose dependently induced NCI16 and PcGST1 mRNAs, but with different profiles. Nickel treatment caused a continuous increase in PcGST1 and NCI16 mRNA levels for up to 3 and 6 days, respectively, and a notable increase in H?O? concentrations in P. caudatum. NCI16 expression was significantly enhanced by incubating cells with H?O?, implying that NCI16 induction in the presence of nickel ions is caused by reactive oxygen species (ROS). On the other hand, PcGST1 was highly induced by the antioxidant tert-butylhydroquinone (tBHQ) but not by H2O2, suggesting that different mechanisms mediate the induction of NCI16 and PcGST1. We introduced a luciferase reporter vector with an ?0.42-kb putative PcGST1 promoter into cells and then exposed the transformants to nickel sulfate. This resulted in significant luciferase upregulation, indicating that the putative PcGST1 promoter contains a nickel-responsive element. Our nickel-inducible system also may be applicable to the efficient expression of proteins that are toxic to host cells or require temporal control. PMID:25001407

  5. Identification of Two Nickel Ion-Induced Genes, NCI16 and PcGST1, in Paramecium caudatum

    PubMed Central

    Haga, Nobuyuki; Nakano, Takanari; Ikeda, Masaaki; Katayama, Shigehiro; Awata, Takuya

    2014-01-01

    Here, we describe the isolation of two nickel-induced genes in Paramecium caudatum, NCI16 and PcGST1, by subtractive hybridization. NCI16 encoded a predicted four-transmembrane domain protein (?16 kDa) of unknown function, and PcGST1 encoded glutathione S-transferase (GST; ?25 kDa) with GST and glutathione peroxidase (GPx) activities. Exposing cells to cobalt chloride also caused the moderate upregulation of NCI16 and PcGST1 mRNAs. Both nickel sulfate and cobalt chloride dose dependently induced NCI16 and PcGST1 mRNAs, but with different profiles. Nickel treatment caused a continuous increase in PcGST1 and NCI16 mRNA levels for up to 3 and 6 days, respectively, and a notable increase in H2O2 concentrations in P. caudatum. NCI16 expression was significantly enhanced by incubating cells with H2O2, implying that NCI16 induction in the presence of nickel ions is caused by reactive oxygen species (ROS). On the other hand, PcGST1 was highly induced by the antioxidant tert-butylhydroquinone (tBHQ) but not by H2O2, suggesting that different mechanisms mediate the induction of NCI16 and PcGST1. We introduced a luciferase reporter vector with an ?0.42-kb putative PcGST1 promoter into cells and then exposed the transformants to nickel sulfate. This resulted in significant luciferase upregulation, indicating that the putative PcGST1 promoter contains a nickel-responsive element. Our nickel-inducible system also may be applicable to the efficient expression of proteins that are toxic to host cells or require temporal control. PMID:25001407

  6. CRADAs: They're Not Just for NCI Anymore | Poster

    Cancer.gov

    By Karen Surabian, Thomas Stackhouse, and Jeffrey Thomas, Contributing Writers, and Bruce Crise, Guest Writer Advancing scientific discovery is increasingly dependent on diverse and innovative partnerships, and the Cooperative Research and Development Agreement (CRADA) is an essential tool for establishing partnerships. CRADAs allow a federal laboratory to enter into collaborative research and development (R&D) projects with outside parties (commercial or nonprofit).

  7. The Anatomy of a Curriculum.

    ERIC Educational Resources Information Center

    Kanter, Hal

    As part of a curriculum development project for gifted students, seventh and tenth grades (N=323) were tested with the Structure of Intellect Learning Abilities Test (SOI-LA) to compare students' scores with norms already collected, investigate differences between the sexes, identify specific types of tasks to promote achievement, and to determine…

  8. NCI Issues and Expands the Cancer Trends Progress Report: 2009/2010 Update

    Cancer.gov

    The NCI released the Cancer Trends Progress Report: 2009/2010 Update. The report, which spans the cancer control continuum from prevention through end of life and summarizes our nation's progress against cancer in relation to the Healthy People† targets developed by the U.S. Department of Health and Human Services, has expanded its focus in this yearís update to include additional info on Medicaid, tobacco marketing, the cost of cancer and other topics.

  9. NCI: SBIR & STTR - Past Funding Opportunities - Contracts - 235 Home Centered Coordinated Cancer Care System

    Cancer.gov

    The Veterans Health Administration, with its enterprise wide computerized patient record, telehealth technologies and coordinated care model, offers a working prototype of a home based system of coordinated care for chronic conditions. The VHA, in partnership with NCI, has developed a system of coordinated cancer care made up of these components. This system has shown promise for the effective management of symptoms and high quality of life during cancer treatment. It has the additional potential of saving costs due to unnecessary institutionalization.

  10. NCI Launches New Initiative to Identify Genetic Risk Factors for Breast and Prostate Cancer

    Cancer.gov

    The National Cancer Institute (NCI), part of the National Institutes of Health, today launched an initiative to identify genetic alterations that make people susceptible to prostate and breast cancer, two of the most commonly diagnosed cancers in the United States. Cancer Genetic Markers of Susceptibility (CGEMS) is a three-year initiative, funded for $14 million, that will conduct scans of the entire human genome (genotyping) to identify common, inherited gene mutations that increase the risks for breast and prostate cancer.

  11. NCI Community Cancer Centers Program - Related Programs - Centers of Excellence in Cancer Communications Research

    Cancer.gov

    The novelty and scope of this initiative reflects the enormous potential of cancer communication to improve health, and NCI's recognition that effective communications can and should be used to narrow the gap between discovery and application and to reduce health disparities among our citizens. It is expected that the Centers' interdisciplinary efforts will result in new theories, methods, and interventions, including those for diverse populations.

  12. NCIís Annual Report on Complementary and Alternative Medicine(CAM)- OCCAM

    Cancer.gov

    The NCI Polyp Prevention Trial (PPT) was a multicenter, randomized clinical trial, with almost 2,000 individuals, that tested whether a diet (high-fiber, low-fat, and high in fruits and vegetables) could prevent the recurrence of precancerous adenomas (polyps) in the colon and rectum. However, the researchers found no preventive effect of the healthy diet on polyp recurrence, even after long-term follow up.

  13. NCIís Annual Report on Complementary and Alternative Medicine(CAM)- OCCAM

    Cancer.gov

    NCIís Polyp Prevention Trial (PPT) was a 4-year randomized trial designed to determine the effect of a low-fat, high-fiber diet high in fruit and vegetables on polyp recurrence. Study participants included more than 2,000 people at high risk for CRC because of a history of polyps. Participants were randomly assigned to follow either their usual diet or the diet high in fruits and vegetables.

  14. NCIís Annual Report on Complementary and Alternative Medicine(CAM)- OCCAM

    Cancer.gov

    Lynette Craft, Ph.D., is a kinesiologist who began her scientific career studying the use of exercise to improve symptoms in patients with clinical depression. However, while pursuing her post-doctoral work at Boston University she had the opportunity to work on an NCI-funded research study ďin which we were primarily looking at physical health outcomes related to exercise involvement with breast cancer patients,Ē she recalled.

  15. Characterization of NCI-H295R cells as an in vitro model of hyperaldosteronism.

    PubMed

    Lichtenauer, U D; Shapiro, I; Osswald, A; Meurer, S; Kulle, A; Reincke, M; Riepe, F; Beuschlein, F

    2013-02-01

    In depth analysis of key molecular mechanisms involved in functional autonomy of aldosterone secretion is hampered by the lack of tumor cell lines that reflect functional characteristics of aldosterone producing adenomas. Herein, we describe the characteristics of the adrenocortical carcinoma cell line NCI-H295R and its suitability as a model of hyperaldosteronism in relation to different culture conditions. Steroid profiling revealed that NCI-H295R cells predominantly secrete cortisol, while aldosterone and other steroids are released at much lower concentrations. However, aldosterone output specifically increased in response to different stimuli such as ACTH and angiotensin II, and in particular to potassium in a dose dependent manner. NCI-H295R cells readily formed spheroids under specific culture conditions, a method widely used for the enrichment of progenitor cells. Unexpectedly, spheroid cells excelled with higher aldosterone concentration and higher expression levels of the steroidogenic enzymes StAR, 3?HSD, CYP17, SF-1, and the MC2-receptor. Further investigations revealed that this phenomenon is mainly attributed to epithelial growth factor (EGF) and particularly fibroblast growth factor (FGF), which are both essential ingredients in the spheroid culture medium. Aldosterone release under the combinatory influence of EGF and FGF was not higher than the effect of FGF alone. Spheroid growth per se, therefore, does not ensure an enrichment of less differentiated cell types in this cell line. PMID:23111829

  16. The NCI Alliance for Nanotechnology in Cancer: achievement and path forward.

    PubMed

    Ptak, Krzysztof; Farrell, Dorothy; Panaro, Nicholas J; Grodzinski, Piotr; Barker, Anna D

    2010-01-01

    Nanotechnology is a 'disruptive technology', which can lead to a generation of new diagnostic and therapeutic products, resulting in dramatically improved cancer outcomes. The National Cancer Institute (NCI) of National Institutes of Health explores innovative approaches to multidisciplinary research allowing for a convergence of molecular biology, oncology, physics, chemistry, and engineering and leading to the development of clinically worthy technological approaches. These initiatives include programmatic efforts to enable nanotechnology as a driver of advances in clinical oncology and cancer research, known collectively as the NCI Alliance for Nanotechnology in Cancer (ANC). Over the last 5 years, ANC has demonstrated that multidisciplinary approach catalyzes scientific developments and advances clinical translation in cancer nanotechnology. The research conducted by ANC members has improved diagnostic assays and imaging agents, leading to the development of point-of-care diagnostics, identification and validation of numerous biomarkers for novel diagnostic assays, and the development of multifunctional agents for imaging and therapy. Numerous nanotechnology-based technologies developed by ANC researchers are entering clinical trials. NCI has re-issued ANC program for next 5 years signaling that it continues to have high expectations for cancer nanotechnology's impact on clinical practice. The goals of the next phase will be to broaden access to cancer nanotechnology research through greater clinical translation and outreach to the patient and clinical communities and to support development of entirely new models of cancer care. PMID:20552623

  17. Web-based stereoscopic visualization for the global anatomy classroom.

    PubMed

    Kaspar, Mathias; Dech, Fred; Parsad, Nigel M; Silverstein, Jonathan C

    2011-01-01

    Many projects have focused on the improvement of virtual education. We have contributed with the global virtual anatomy course for teaching students in multiple locations with stereoscopic volume rendering, audio/video conferencing and additional materials. This year we focused on further simplifying the deployment of the classroom by using the new collaborative and web-based visualization system CoWebViz, to transfer stereoscopic visualization to the classrooms. Besides the necessary hardware installations for stereoscopy, only a web browser is necessary to view and to interact with the remote 3D stereo visualization. This system proved stable, gave higher quality images and increased ease of deployment. Its success within our classroom at the University of Chicago and Cardiff University has motivated us to continue CoWebViz development. PMID:21335801

  18. NON Community Networks Program Centers (CNPC) and NCI Community Oncology Research Program (NCORP) Projects

    Cancer.gov

    Strengthen the use of evidence-based education, outreach, and dissemination using the Community Guide, as well as partnership and capacity building, to improve knowledge, behavior, attitude, and beliefs with focus on the early detection of breast, cervical, and colorectal cancers, clinical trial and biospecimen research.

  19. Mouse anatomy ontologies: enhancements and tools for exploring and integrating biomedical data.

    PubMed

    Hayamizu, Terry F; Baldock, Richard A; Ringwald, Martin

    2015-10-01

    Mouse anatomy ontologies provide standard nomenclature for describing normal and mutant mouse anatomy, and are essential for the description and integration of data directly related to anatomy such as gene expression patterns. Building on our previous work on anatomical ontologies for the embryonic and adult mouse, we have recently developed a new and substantially revised anatomical ontology covering all life stages of the mouse. Anatomical terms are organized in complex hierarchies enabling multiple relationships between terms. Tissue classification as well as partonomic, developmental, and other types of relationships can be represented. Hierarchies for specific developmental stages can also be derived. The ontology forms the core of the eMouse Atlas Project (EMAP) and is used extensively for annotating and integrating gene expression patterns and other data by the Gene Expression Database (GXD), the eMouse Atlas of Gene Expression (EMAGE) and other database resources. Here we illustrate the evolution of the developmental and adult mouse anatomical ontologies toward one combined system. We report on recent ontology enhancements, describe the current status, and discuss future plans for mouse anatomy ontology development and application in integrating data resources. PMID:26208972

  20. The history of anatomy in Persia.

    PubMed

    Shoja, Mohammadali M; Tubbs, R Shane

    2007-04-01

    The study of human anatomy can be found throughout the rich history of Persia. For thousands of years, morphological descriptions derived from this part of the world have contributed to and have helped form our current anatomical knowledge base. In this article we review the major influential Persian periods and the individuals who have contributed to the development of anatomy. We have divided the history of Persia into five eras: (1) the period of the Elamites, Medes, early Persians and Babylonians (10th millennium to 6th century BC); (2) following the establishment of the Persian Empire (6th century BC) to the 7th century AD; (3) after the Islamic conquest of Persia to the ascendency of Baghdad (7th to 13th century AD); (4) from the Mongol invasion of Persia to the foundations of modern anatomy (13th to 18th century AD); and (5) modern Persia/Iran (18th century AD to present). Evidence indicates that human dissection was commonplace in the first era, which led to a disciplined practice of surgery in the centuries leading to the foundation of the Persian Empire. By the emergence of Zoroastrianism in the Persian Empire, the microcosm theory was widely used to understand internal anatomy in relation to the external universe. The world's first cosmopolitan university and hospital were built in Gondishapur, south-western Persia, in the third century AD. Greek and Syriac knowledge influenced the second era. With the gradual ruin of Gondishapur and the foundation of Baghdad following the Islamic conquest of Persia (637-651 AD), a great movement took place, which led to the flourishing of the so-called Middle Age or Islamic Golden Age. Of the influential anatomists of this period, Mesue (777-857 AD), Tabbari (838-870 AD), Rhazes (865-925 AD), Joveini (?-983 AD), Ali ibn Abbas (930-994 AD), Avicenna (980-1037 AD) and Jorjani (1042-1137 AD) all hailed from Persia. There is evidence in the Persian literature as to the direct involvement of these scholars in human dissection. Syro-Indian, Byzantine, Greek, Chinese and Arabic knowledge all influenced the third era. In the fourth period, the first colour illustrated anatomical text (by Mansur, 14th century AD) was compiled. Chinese and Indian anatomical styles were embraced, though there was a strong religious siege of anatomy late in this era. By the 19th century, Persia had entered a new era of modernizing movements and academic contact with the West through the reforms of Mirza Tagi Khan Amir Kabir. Knowledge of anatomy for this region in the 20th century was greatly influenced by Europe and America. PMID:17428200