Sample records for aps press release

  1. PRESS RELEASE / PRESS RELEASE / PRESS RELEASE / PRESS RELEASE Herv Biausser, Director of the Ecole Centrale Paris,

    E-print Network

    Paragios, Nikos

    PRESS RELEASE / PRESS RELEASE / PRESS RELEASE / PRESS RELEASE Hervé Biausser, Director of the Ecole since 2004. The governing body of Supélec has offered Hervé BIAUSSER, Director of the Ecole Centrale. ___________________________________________________________________________________ Press Contact: Ecole Centrale Paris Supélec Mr. Etienne DAGES-DESGRANGES Ms. Mariane DUBIEZ Telephone

  2. Press Release Writing

    NSDL National Science Digital Library

    As expected, Press Release Writing, from Accurate Online Solutions, offers a helpful tutorial on the art of press release writing. The advice is broken into several easily digestible sections, covering the main themes of the advertising vs. public relations debate, essentials of writing press releases, templates, formats, and samples. The site also offers comprehensive distribution lists for all media formats including electronic media, magazines, newspapers, wire services, and television stations. Interested users will want to subscribe to the free Press Release Writing enewsletter.

  3. Press Release FOR IMMEDIATE RELEASE

    E-print Network

    Tam, Vincent W. L.

    Press Release FOR IMMEDIATE RELEASE Page 1 of 2 HKU student wins British Council FameLab contest to victory in the second FameLab science communication competition held in Hong Kong, beating six other Science Museum on Saturday (20 November). He had three minutes to convince judges of his chosen scientific

  4. Press Release: Health Services

    E-print Network

    New Hampshire, University of

    population recently recognized the University of New Hampshire's Student Health Benefits Plan (http successful management features such as direct contracting with local health care providers or adoption Press Release: Health Services University of New Hampshire 12 Ballard

  5. Press Release Basic Design

    E-print Network

    Stell, John

    Press Release Basic Design The pioneering art education work of Leeds College of Art is under of a wider research project called `Art School Educated' that looks at the vital role the Basic Design course the mid 1950's Leeds College of Art led the way in the Basic Design movement, which was a new and radical

  6. PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY

    E-print Network

    Cai, Long

    PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY (http://www.nature.com/tp/) This press release is copyrighted to the journal Translational Psychiatry Its use is granted only for journalists and news media of 1934. PICTURES: While we are happy for images from Translational Psychiatry to be reproduced

  7. PRESS RELEASE FROM MOLECULAR PSYCHIATRY

    E-print Network

    Cai, Long

    PRESS RELEASE FROM MOLECULAR PSYCHIATRY (http://www.nature.com/mp) For papers that will be published online on 21 February 2012 This press release is copyrighted to the journal Molecular Psychiatry Exchange Act of 1934. PICTURES: While we are happy for images from Molecular Psychiatry to be reproduced

  8. PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY

    E-print Network

    Cai, Long

    PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY (http://www.nature.com/tp/) This press release is copyrighted to the journal Translational Psychiatry Its use is granted only for journalists and news media Translational Psychiatry to be reproduced for the purposes of contemporaneous news reporting, you must also seek

  9. PRESS RELEASE FROM MOLECULAR PSYCHIATRY

    E-print Network

    Cai, Long

    PRESS RELEASE FROM MOLECULAR PSYCHIATRY (http://www.nature.com/mp) For papers that will be published online on 30 August 2011 This press release is copyrighted to the journal Molecular Psychiatry Exchange Act of 1934. PICTURES: While we are happy for images from Molecular Psychiatry to be reproduced

  10. PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY

    E-print Network

    Cai, Long

    PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY (http://www.nature.com/tp/) This press release is copyrighted to the journal Translational Psychiatry Its use is granted only for journalists and news media: While we are happy for images from Translational Psychiatry to be reproduced for the purposes

  11. PRESS RELEASE FROM MOLECULAR PSYCHIATRY

    E-print Network

    Cai, Long

    PRESS RELEASE FROM MOLECULAR PSYCHIATRY (http://www.nature.com/mp) For a paper that will be published online on 09 August 2011 This press release is copyrighted to the journal Molecular Psychiatry of 1934. PICTURES: While we are happy for images from Molecular Psychiatry to be reproduced

  12. Press Release Corporate Communications

    E-print Network

    Haller-Dintelmann, Robert

    coal-fired, natural-gas-fired, waste-derived-fuel-fired, and biomass-fired, power plants to reliably.ch@pvw.tu-darmstadt.de www.tu-darmstadt.de/presse presse@tu-darmstadt.de "A Milestone Along the Way to CO2-Free Power Plants" An innovative method inexpensively and energetically efficiently reduces power-plant CO2-emissions by more than

  13. PRESS RELEASE FROM NEUROPSYCHOPHARMACOLOGY

    E-print Network

    Cai, Long

    of newsworthy papers: Increased glutamate in women with postpartum depression ADHD medications do not increase likelihood of drug addiction A PDF of the paper mentioned on this release can be found in the Academic of this release. Warning: This document, and the Academic Journal paper to which it refers, may contain

  14. MAX PLANCK SOCIETY Press Release

    E-print Network

    MAX PLANCK SOCIETY Press Release SP / 2004 (1) January 15th, 2004 Max Planck Society at the American Astronomical Society meeting in Atlanta, Georgia. Dr. Eric F. Bell of the Max-Planck consortium and led by Dr. Hans-Walter Rix, Director of the Max-Planck-Institute for Astronomy, said the image

  15. PRESS RELEASE January 28, 2013

    E-print Network

    Weston, Ken

    PRESS RELEASE January 28, 2013 Media Contact Becky Kelly, FSU Panama City, Office of Advancement at (850) 770-2151 or rkelly@pc.fsu.edu. FLORIDA STATE UNIVERSITY PANAMA CITY SUMMER SCUBA LAB Panama City, FL--The Advanced Science Diving Program at Florida State University Panama City is offering a Summer

  16. PRESS RELEASE February 13, 2013

    E-print Network

    Weston, Ken

    PRESS RELEASE February 13, 2013 Media Contact Becky Kelly, FSU Panama City, Office of Advancement at (850) 770-2151 or rkelly@pc.fsu.edu. FLORIDA STATE UNIVERSITY PANAMA CITY SUMMER STEM CAMPS Panama City, FL--Florida State University Panama City STEM Institute's Summer STEM Camps are open to rising 8th

  17. Press Release Date: November 2013

    E-print Network

    Stell, John

    Press Release Date: November 2013 Boyd and Evans exhibition 28 November 3 January 2013, Blenheim we started out on our journey as collaborators were feelings for representation, painting, narrative of digital pictures. Our attitude to photography is as painterly as our paintings are photographic. We use

  18. PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY

    E-print Network

    Cai, Long

    PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY (http://www.nature.com/tp/) For papers Psychiatry Its use is granted only for journalists and news media receiving it directly from the Nature Psychiatry to be reproduced for the purposes of contemporaneous news reporting, you must also seek permission

  19. Press Release 22 August 2006

    E-print Network

    Press Release 22 August 2006 NICTA and Ericsson sign three-year research agreement National ICT Australia (NICTA) and Ericsson today announced a three-year umbrella agreement for research into next is with Ericsson's global research arm and is initially valued at AUD$2.7 million with scope for expansion. Tony

  20. How to write a press release

    NSDL National Science Digital Library

    Greg Dart

    2007-10-19

    This project teaches Snow College students how to write a press release Writing a press release can be the most important skill an public releations pro cna master. Being able to write an effective press release will make you much more employable than your classmates and will help you land that big first job. Following the completion of this tutorial, students will be ...

  1. Joint Press Release TWELFTH ITER NEGOTIATION MEETING

    E-print Network

    Joint Press Release TWELFTH ITER NEGOTIATION MEETING Jeju, Korea, 6 December th 2005 Delegations on an Agreement on the joint implementation of the ITER international fusion energy project. This was the first/6/05 1:21 PMDraft Joint News Release Page 1 of 2http://www.iter.org/N_12_Joint_Press_Release.htm #12

  2. In the Stocks: Perilous Press Releases.

    ERIC Educational Resources Information Center

    Morton, Linda P.; Loving, Bill

    1994-01-01

    Reviews some of the legal responsibilities of public relations practitioners in the preparation of press releases. Discusses legal criteria for judging the fraudulence of press releases and discusses the timeframe for fraudulent action. Concludes with lessons that practitioners need to understand. (SR)

  3. Press Release End of Year Show 2013

    E-print Network

    Stell, John

    Press Release End of Year Show 2013 Published 4 th July Record numbers of guests attended our End press coverage, featuring live on BBC1's Look North on the Private View evening. Alex Dodgson BA (Hons) Fine Art third year student performed live, using his body as a canvas and encouraging visitors

  4. MATHEMATICS OF PLANET EARTH PRESS RELEASE

    E-print Network

    MATHEMATICS OF PLANET EARTH PRESS RELEASE MARCH 5 2013 MATHEMATICS OF PLANET EARTH DAY AT UNESCO Paris (France) March 5 2013 in a major world-wide initiative: Mathematics of Planet Earth 2013 (MPE2013). This year

  5. Press Release EGU Press Release 04.01 EGU Contact: Dick van der Wateren

    E-print Network

    Renssen, Hans

    Press Release EGU Press Release 04.01 EGU Contact: Dick van der Wateren 17 March 2004 egu Drilling Project Leg 208. The ODP cruise, led by Dick Kroon of the Vrije Universiteit, Amsterdam, and James the first time, a group of scientists from the Vrije Universiteit Amsterdam, including Dick Kroon

  6. Press Release Images for Spirit and Opportunity

    NSDL National Science Digital Library

    NASA's Jet Propulsion Laboratory

    This NASA website provides links to press release images, maps, and graphics with extensive captions of the "Spirit" and "Opportunity" Rover missions. Downloads of images and graphics at various resolutions are also available here. Images are catalogued separately by release date for both Spirit and Opportunity.

  7. Press Release For Immediate Release Contact: Jennifer Morcone, CDC

    E-print Network

    Press Release For Immediate Release Contact: Jennifer Morcone, CDC March 14, 2005 404 harbor these infectious organisms. CDC asks swimmers to forego swimming when they have diarrhea, which in diapers are advised to keep their children out of the pool if they have diarrhea. CDC also recommends

  8. Press Release Date: Wednesday 5 February 2014

    E-print Network

    Stell, John

    Press Release Date: Wednesday 5 February 2014 PAN Berlin Record label 14 February 16 May Blenheim showcases a range of artwork produced by the label for PAN artists' records. Founded in 2008 by artist Bill artists over its four year lifespan. The beautiful artwork is a critical part of its success, and

  9. Press Release Fingerprints of higher brain functions

    E-print Network

    Tübingen, Universität

    Seite 1/3 Press Release Fingerprints of higher brain functions Neuroscientists uncover novel during information processing, may be `fingerprints' of these basic calculations. Such basic calculations of brainwaves, also known as oscillations, are `spec- tral fingerprints' of canonical neuronal computations

  10. Ten Ways to Get Attention with Your Press Releases.

    ERIC Educational Resources Information Center

    Van Kooten, Valerie

    1994-01-01

    Recommends 10 steps that can increase chances of having press release published. Advises readers to use required format; determine what constitutes news; keep release short; include contact person in release; incorporate good quotes; send releases to right person; understand that release will be edited; time arrival of release; follow up with

  11. Press Releases vs. Newspaper Coverage of California Supreme Court Decisions.

    ERIC Educational Resources Information Center

    Hale, F. Dennis

    1978-01-01

    A study comparing the coverage in newspapers and press releases regarding one year's decisions of the California Supreme Court revealed that the press releases influenced the kinds of decisions that were reported but not the quantity of coverage by the newspapers. (GT)

  12. Hypoxia Press Release and Map - August 1, 2005

    NSDL National Science Digital Library

    EPA- Gulf of Mexico Program Office

    This EPA press release documents the findings of a 2005 mapping project in the Gulf of Mexico low-oxygen waters. The article notes the extent of the "dead zone" and notes the possible effects of Hurricane Dennis on the hypoxic zone. It also reports a smaller than expected nitrate content in the dead zone, which was attributed to the below average precipitation in the Mississippi River Basin. The press release also features a color map of the dead zone's extent.

  13. EUROPA > European Commission > Press Room > Press Releases Contact | Search on EUROPA SearchSelect a topicMidday Express Recent Press Releases

    E-print Network

    English EUROPA > European Commission > Press Room > Press Releases Contact | Search on EUROPA exploring a `broader approach to fusion power' involving other international activities complementing Japan. http://europa.eu.int/comm/research/energy/fu/article_1122_en.htm http://www.iter.org/ Page 2 sur

  14. After the Highwayman: Syntax and Successful Placement of Press Releases in Newspapers.

    ERIC Educational Resources Information Center

    Walters, Timothy N.; And Others

    1994-01-01

    Compares the grammatical structure of original press releases with the resultant placements in daily newspapers. Finds that, in their use of press releases, journalists almost always have to make them simpler, shorter, easier to read, and less passive. (SR)

  15. An Exploratory Study of Credibility Issues in Astronomy Press Releases

    Microsoft Academic Search

    Lars Lindberg Christensen; Lars Holm Nielsen; Nanna Torpe Jrgensen; Kim Jantzen

    Summary Current developments in the media marketplace and an increased need for visibility to secure funding are leading inevitably to faster, simpler and more aggressive science communication. This article presents the results of an exploratory study of potential credibility problems in astronomy press releases, their causes, consequences and possible remedies. The study consisted of eleven open-ended interviews with journalists, scientists

  16. Press Release Law School Honors Top Student Scholars

    E-print Network

    Dasgupta, Dipankar

    Press Release Law School Honors Top Student Scholars Three student editors of the University's annual banquet, held at the Rock & Soul Museum. A law review "note" is a lengthy, deeply researched we have done in law school, by far, so being recognized for our legal scholarship is very rewarding

  17. Press Release Law School Honors Top Student Scholars

    E-print Network

    Dasgupta, Dipankar

    Press Release Law School Honors Top Student Scholars Three student editors of the University banquet, held at the Rock & Soul Museum. A law review "note" is a lengthy, deeply researched, and heavily school, by far, so being recognized for our legal scholarship is very rewarding. It's thrilling to know

  18. Press Release People ate mammoth, dogs got reindeer

    E-print Network

    Grust, Torsten

    the "palaeolithic dogs" fit into this subsistence picture. They found that humans did consume mammoth and in large;Page 2/3 Simplified prey-predator relationships for prehistoric humans and large mammals in Pedmost IPage 1/3 Press Release People ate mammoth, dogs got reindeer Tbingen biogeologists show how

  19. Press Releases and News Analysis: Asia ETF risk under watch

    E-print Network

    Chaudhuri, Sanjay

    Press Releases and News Analysis: Asia ETF risk under watch after UBS rogue trades Comment By RMI. Banks across the region, which have been busy peddling Asia-focused exchange traded funds (ETFs to financial industry sources in Hong Kong and Singapore. Asia-focused ETFs are unique in that they allow

  20. NASA Press Releases and Mission Statements: Exploring the mathematics

    E-print Network

    -grade-level learners in grades 3-12. Key Words: Mathematics problems; space; astronomy; press releases; newspapers goals to be determined by each state. Each student will be subjected to frequent assessments, and teachers will be required to systematically improve classroom performance on these assessments while

  1. NSF Web Site Press Release 10-018

    E-print Network

    Rogers, John A.

    NSF Web Site Press Release 10-018 NSF Submits Its Fiscal Year 2011 Budget Request of $7.4 Billion February 1, 2010 In its 60th anniversary year, the National Science Foundation (NSF) today submitted investment in research and development to at least 3 percent of the gross domestic product. NSF Director

  2. Vesicles derived via AP-3 dependent recycling contribute to asynchronous release and influence information transfer

    PubMed Central

    Evstratova, Alesya; Chamberland, Simon; Faundez, Victor; Tth, Katalin

    2014-01-01

    Summary Action potentials trigger synchronous and asynchronous neurotransmitter release. Temporal properties of both types of release could be altered in an activity-dependent manner. While the effects of activity-dependent changes in synchronous release on postsynaptic signal integration have been studied, the contribution of asynchronous release to information transfer during natural stimulus patterns is unknown. Here we find that during trains of stimulations, asynchronous release contributes to the precision of action potential firing. Our data show that this form of release is selectively diminished in AP-3b2 KO animals, which lack functional neuronal AP-3, an adaptor protein regulating vesicle formation from endosomes generated during bulk endocytosis. We find that in the absence of neuronal AP-3, asynchronous release is attenuated and the activity-dependent increase in the precision of action potential timing is compromised. Lack of asynchronous release decreases the capacity of synaptic information transfer and renders synaptic communication less reliable in response to natural stimulus patterns. PMID:25410111

  3. 7 CFR 550.29 - Press releases.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...public notification will be submitted to the REE agency for review prior to release to the public. The REE Agency will be given the opportunity to...necessary, if the material mentions by name the REE Agency or the USDA, or any USDA employee...

  4. 7 CFR 550.29 - Press releases.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...public notification will be submitted to the REE agency for review prior to release to the public. The REE Agency will be given the opportunity to...necessary, if the material mentions by name the REE Agency or the USDA, or any USDA employee...

  5. 7 CFR 550.29 - Press releases.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...public notification will be submitted to the REE agency for review prior to release to the public. The REE Agency will be given the opportunity to...necessary, if the material mentions by name the REE Agency or the USDA, or any USDA employee...

  6. 7 CFR 550.29 - Press releases.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...public notification will be submitted to the REE agency for review prior to release to the public. The REE Agency will be given the opportunity to...necessary, if the material mentions by name the REE Agency or the USDA, or any USDA employee...

  7. 7 CFR 550.29 - Press releases.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...public notification will be submitted to the REE agency for review prior to release to the public. The REE Agency will be given the opportunity to...necessary, if the material mentions by name the REE Agency or the USDA, or any USDA employee...

  8. Money Income in the United States: 1998 (Press release)

    NSDL National Science Digital Library

    This press release from the US Census Bureau announces that the number of Americans living under the poverty level dropped to 12.7 percent in 1998. This marks the fourth year in a row in which the median household income has risen. The reports, Money Income in the United States: 1998 and Poverty in the United States: 1998 break the data down demographically and highlight some of the more inclusive findings.

  9. Processing map for controlling microstructure in hot working of hot isostatically pressed powder metallurgy NIMONIC AP1 superalloy

    Microsoft Academic Search

    M. C. Somani; E. S. Bhagiradha Rao; N. C. Birla; M. L. Bhatia; Vakil Singh; Y. V. R. K. Prasad

    1992-01-01

    The hot deformation behavior of hot isostatically pressed (HIP) NIMONIC AP-1 superalloy is characterized using processing\\u000a maps in the temperature range 950 ?C to 1200 ?C and strain rate range 0.001 to 100 s1. The dynamic materials model has been used for developing the pro-cessing maps which show the variation of the efficiency\\u000a of power dissipation given by [2m\\/ (m

  10. Framing the Candidates in Presidential Primaries: Issues and Images in Press Releases and News Coverage.

    ERIC Educational Resources Information Center

    Miller, M. Mark; Andsager, Julie L.; Riechert, Bonnie P.

    1998-01-01

    Contributes to research on political communication by examining how 1996 GOP presidential candidates framed themselves in press releases and how elite newspapers covered them. Shows that candidate images were distinct in press releases and news stories; candidate positions were represented differently in both; and candidates were differentially

  11. PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY (http://www.nature.com/tp)

    E-print Network

    Cai, Long

    PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY (http://www.nature.com/tp) This press release is copyrighted to the journal Translational Psychiatry. Its use is granted only for journalists and news media to penalties and imprisonment. PICTURES: While we are happy for images from Translational Psychiatry

  12. PRESS RELEASE FROM MOLECULAR PSYCHIATRY (http://www.nature.com/mp)

    E-print Network

    Cai, Long

    PRESS RELEASE FROM MOLECULAR PSYCHIATRY (http://www.nature.com/mp) This press release is copyrighted to the journal Molecular Psychiatry. Its use is granted only for journalists and news media we are happy for images from Molecular Psychiatry to be reproduced for the purposes

  13. PRESS RELEASE FROM MOLECULAR PSYCHIATRY (http://www.nature.com/mp)

    E-print Network

    Cai, Long

    PRESS RELEASE FROM MOLECULAR PSYCHIATRY (http://www.nature.com/mp) This press release is copyrighted to the journal Molecular Psychiatry. PLEASE CITE MOLECULAR PSYCHIATRY AND THE MOLECULAR PSYCHIATRY with the amount of time people spend sleeping are identified this week in Molecular Psychiatry. Sleeping outside

  14. APS Receives Continued Funding from NIDDK

    NSDL National Science Digital Library

    APS Communications Office (American Physiological Society Communications Office)

    2010-09-22

    Press Release - BETHESDA, MD (September 22, 2010)? The American Physiological Society (APS; www.the-APS.org) has received continued funding from the National Institute of Diabetes and Digestive and Kidney Disease (NIDDK) for an additional two years of support effective July 1, 2010. The goal of the project is to encourage highly qualified students from groups underrepresented in the biomedical/behavioral sciences (especially underrepresented minority students) to pursue professional careers in physiological/biomedical sciences.

  15. Press Releases of Science Journal Articles and Subsequent Newspaper Stories on the Same Topic

    NSDL National Science Digital Library

    de Semir, Valdimir.

    1998-01-01

    This article from Journal of the American Medical Association (JAMA) documents how scientific news is made and perpetuated. The authors found evidence that "journal articles described in press releases, in particular those described first or second in the press release, are associated with the subsequent publication of newspaper stories on the same topic." Though not a surprising result, the article offers insights into why and what the public considers important in science.

  16. Credibility of science communication: An exploratory study of astronomy press releases Credibility of science communication: An exploratory study of astronomy press releases

    Microsoft Academic Search

    Lars Holm Nielsen; Nanna Torpe Jrgensen; Kim Jantzen; Lars Lindberg Christensen

    Current developments in the media marketplace and an increased need for visibility to secure funding are leading inevitably to faster, simpler and more aggressive science communication. This article presents the results of an exploratory study of potential credibility problems in astron- omy press releases, their causes, consequences and possible remedies. The study consisted of eleven open-ended interviews with journalists, scientists

  17. PressRelease|TheFitzwilliamMuseum Trumpington Street

    E-print Network

    Zeki, Semir

    .fitzmuseum.cam.ac.uk Press enquiries: email fitzmuseum-press@lists.cam.ac.uk - continues - The Search for Immortality: Tomb for immortality and struggle for imperial legitimacy in ancient China's Han Dynasty. The Search for Immortality by clay guardians and surrounded by jade and gold, the monarchs' tombs were palaces fit for immortals

  18. PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY (http://www.nature.com/tp)

    E-print Network

    Cai, Long

    PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY (http://www.nature.com/tp) For papers that will be published online on 9 July 2013 Thispress release iscopyrighted to the Translational Psychiatry. Itsuse the specific example. PLEASE CITE TRANSLATIONAL PSYCHIATRY AS THE SOURCE OF THE FOLLOWING ITEM. IF PUBLISHING

  19. PressRelease|TheFitzwilliamMuseum Trumpington Street

    E-print Network

    Zeki, Semir

    and dispossession to those of Jewish origin such as Frankl and his family. Frankl and his wife Christine were among information and images contact the Marketing and Press Office: Telephone: 01223 332941 | Email: fitzmuseum

  20. PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY AND MOLECULAR For papers that will be published on online 04 October 2011

    E-print Network

    Cai, Long

    PRESS RELEASE FROM TRANSLATIONAL PSYCHIATRY AND MOLECULAR PSYCHIATRY For papers that will be published on online 04 October 2011 This press release is copyrighted to Translational Psychiatry and Molecular Psychiatry. Its use is granted only for journalists and news media receiving it directly from

  1. Processing map for controlling microstructure in hot working of hot isostatically pressed powder metallurgy NIMONIC AP-1 superalloy

    NASA Astrophysics Data System (ADS)

    Somani, M. C.; Rao, E. S. Bhagiradha; Birla, N. C.; Bhatia, M. L.; Singh, Vakil; Prasad, Y. V. R. K.

    1992-10-01

    The hot deformation behavior of hot isostatically pressed (HIP) NIMONIC AP-1 superalloy is characterized using processing maps in the temperature range 950 C to 1200 C and strain rate range 0.001 to 100 s1. The dynamic materials model has been used for developing the pro-cessing maps which show the variation of the efficiency of power dissipation given by [2m / ( m + 1)] with temperature and strain rate, with m being the strain rate sensitivity of flow stress. The processing map revealed a domain of dynamic recrystallization with a peak efficiency of 40 pct at 1125 C and 0.3 s1, and these are the optimum parameters for hot working. The microstructure developed under these conditions is free from prior particle boundary (PPB) de-fects, cracks, or localized shear bands. At 100 s1 and 1200 C, the material exhibits inter-crystalline cracking, while at 0.001 s1, the material shows wedge cracks at 1200 C and PPB cracking at 1000 C. Also at strain rates higher than 10 s1, adiabatic shear bands occur; the limiting conditions for this flow instability are accurately predicted by a continuum criterion based on the principles of irreversible thermodynamics of large plastic flow.

  2. Credibility of science communication: An exploratory study of astronomy press releases

    Microsoft Academic Search

    L. H. Nielsen; N. Torpe Jrgensen; K. Jantzen; L. L. Christensen

    2008-01-01

    Current developments in the media marketplace and an increased need for visibility to secure funding are leading inevitably to faster, simpler and more aggressive science communication. This article presents the results of an exploratory study of potential credibility problems in astronomy press releases, their causes, consequences and possible remedies. The study consisted of eleven open-ended interviews with journalists, scientists and

  3. Press release: 18 September 2014 Curating Cambridge: our city, our stories, our stuff

    E-print Network

    Cambridge, University of

    Press release: 18 September 2014 Curating Cambridge: our city, our stories, our stuff 20 October will open for Curating Cambridge: our city, our stories, our stuff, a five week festival of fun the Cambridge Festival of Ideas website. If pub quizzes are your thing don't miss Things of Cambridge: A Pub

  4. Press Release: The Caribbean Philosophical Association (CPA) is pleased to announce the election of

    E-print Network

    Alpay, S. Pamir

    Press Release: The Caribbean Philosophical Association (CPA) is pleased to announce the election: http://www.caribbeanphilosophicalassociation.org/index.html And on facebook: http://www.facebook.com/pages/CPA-Caribbean (Fordham UP, 2013). Her articles have appeared in the C.L.R. James Journal: A Review of Caribbean Ideas

  5. Press Releases and News A financial crisis will dry up stocks

    E-print Network

    Chaudhuri, Sanjay

    Press Releases and News A financial crisis will dry up stocks RMI Affiliated Researcher Prof dries up during periods of financial crisis. What can Singapore learn from this? Financial markets selling and/or financial intermediaries withdraw from providing liquidity. For example, a rapid decline

  6. PRESS RELEASE FROM NATURE PUBLISHING GROUP The Macmillan Building 20 December 2007 4 Crinan Street

    E-print Network

    Cai, Long

    .nature.com/ngeo/press_releases/ngeo1207.html "Nature Geoscience is an important new journal for Nature Publishing Group. It strengthens for NPG." A monthly multi-disciplinary journal, Nature Geoscience is aimed at bringing together top journals, Nature Reviews, Nature Clinical Practice and a range of prestigious academic journals including

  7. PRESS RELEASE Charles University in Prague opens its doors wide to the world -computer science

    E-print Network

    Cerveny, Vlastislav

    PRESS RELEASE Charles University in Prague opens its doors wide to the world - computer science course in computer science in English. In 1952, when the Faculty of Mathematics and Physics, Charles's and master's study programs in computer science with English as the language of instruction. Attention

  8. Press Release Monday October 5th, 2009 UHM Scientists Spark Aerospace in Hawaii

    E-print Network

    Press Release Monday October 5th, 2009 UHM Scientists Spark Aerospace in Hawaii Week Researchers from the School of Ocean and Earth Sciences and Technology at the University of Hawaii at Manoa will participate in lively panel discussions this week as part of Aerospace Week in Hawaii. All presentations

  9. PRESS RELEASES OF SENATOR PETE DOMENICI Domenici Supports 12 Percent Increase for Nuclear Energy, Disputes Fusion

    E-print Network

    PRESS RELEASES OF SENATOR PETE DOMENICI Domenici Supports 12 Percent Increase for Nuclear Energy his support for a 12 percent increase in federal funding for nuclear energy research, but challenged of modern nuclear power plants. Domenici is chairman of the Energy and Water Development Appropriations

  10. Chorum Press Releases Page 1 of 2 http://www.chorumtech.com/news-releases/NewsReviews_jc.poster.htm 2/25/2002

    E-print Network

    Chiao, Jung-Chih

    Chorum Press Releases Page 1 of 2 http://www.chorumtech.com/news-releases/NewsReviews_jc.poster.htm 2/25/2002 FOR IMMEDIATE RELEASE CHORUM TECHNOLOGIES' DR. J.C. CHIAO TO PRESENT PAPER IN THE POSTER WHAT: Dr. J.C. Chiao from Chorum Technologies in Richardson, Texas, will present a paper in the poster

  11. OFFICE OF COMMUNICATIONS PRESS RELEASE NOVEMBER 4, 2010

    E-print Network

    Wechsler, Risa H.

    the release of calcium ions from a storehouse within skeletal- muscle and heart-muscle cells as needed of the cell. In skeletal muscles, the timing of the pulses is determined by how often the muscles contract. In skeletal muscle, this can lead to fatal rises in body temperature under certain anesthetics, or the failure

  12. An Extraction Method of Product Feature Keywords From Press Releases Using Syntactic Dependency Analysis with an Expression Phrase

    NASA Astrophysics Data System (ADS)

    Samejima, Masaki; Shimizu, Yutaka; Akiyoshi, Masanori; Komoda, Norihisa

    We propose an extraction method of product features from press releases of companies for competitor analysis. In press releases of companies, product features are described with characteristic expressions (we call description patterns). From this view point, when a description pattern is input, our system extracts features included in the pattern. Additionally, in order to extract more product features by less input patterns, our system generates similar patterns of input patterns as derivation patterns automatically and extracts product features using derivation patterns. Through application to the press releases of ten companies, it is confirmed that the accuracy of the extracted features are sufficient.

  13. Solid-state diffusion welding of wrought AISI 304 stainless steel to Nimonic AP-1 superalloy powder by hot isostatic pressing

    SciTech Connect

    Somani, M.C.; Birla, N.C. [Defence Metallurgical Research Lab., Hyderabad (India); Tekin, A. [Istanbul Technical Univ., Istanbul (Turkey). Dept. of Chemical and Metallurgical Engineering

    1998-02-01

    The diffusion welding characteristics of wrought AISI 304 stainless steel to a superalloy powder Nimonic AP-1 were examined in this study. After encapsulation, evacuation and degassing, the welds were hot isostatically pressed (HIPed) in two different cycles, i.e., 1,200 C (2,192 F)/3h/147 MPa and 1,270 C (2,318 F)/3h/121 MPa. A variation in surface condition of stainless steel was also studied for its influence on properties of the joints. These diffusion-welded joints were characterized for diffusion of alloying elements, microstructural features and tensile properties.

  14. Studies on applicability of press-coated tablets using hydroxypropylcellulose (HPC) in the outer shell for timed-release preparations

    Microsoft Academic Search

    Eiji Fukui; Katsuji Uemura; Masao Kobayashi

    2000-01-01

    Press-coated tablets, containing diltiazem hydrochloride (DIL) in the core tablet and coated with hydroxypropylcellulose (HPC) as the outer shell, were examined for applicability as timed-release tablets with a predetermined lag time and subsequent rapid drug release phase. Various types of press-coated tablets were prepared using a rotary tabletting machine and their DIL dissolution behavior was evaluated by the JP paddle

  15. Outrage Factors in Government Press Releases of Food Risk and Their Influence on News Media Coverage.

    PubMed

    Ju, Youngkee; Lim, Jeongsub; Shim, Minsun; You, Myoungsoon

    2015-08-01

    An appropriate level of risk perception should be a critical issue in modern "risk society." There have been many studies on the influences on risk perception. This study investigates whether risk communication scholar Dr. Peter Sandman's outrage factors intensify journalistic attention to health risks from food consumption. A content analysis of a health institution's press releases was conducted to examine 15 outrage factors of food risks conveyed in the governmental risk communication. In addition, the news stories covering the food risks informed by the press releases were calculated to evaluate the relation between outrage factors of a risk and the number of news stories covering the risk. Results showed that controllability was the most salient outrage factor, followed by trust, voluntariness, familiarity, and human origin; the greater the outrage score of a risk, the more news stories of the risk. For individual outrage factors, a risk with an implication of catastrophic potential was associated with an increase of news stories. Food providers' distrustful behaviors also influenced journalistic attention to the food risks. The implication of the findings to health message designers is discussed. PMID:26065830

  16. Megaconference V Reaches Five Continents http://www.osc.edu/press/releases/2003/megaconference.shtml 1 of 3 9/19/2008 12:34 PM

    E-print Network

    Calyam, Prasad

    Megaconference V Reaches Five Continents http://www.osc.edu/press/releases/2003/megaconference "Dr. Bob"), Senior Network Engineer for OSC Networking and Chief Research Engineer for The Ohio State Reaches Five Continents http://www.osc.edu/press/releases/2003/megaconference.shtml 2 of 3 9/19/2008 12

  17. Coverage of Team Science by Public Information Officers: Content Analysis of Press Releases about the National Science Foundation Science and Technology Centers

    ERIC Educational Resources Information Center

    Graube, Marita; Clark, Fiona; Illman, Deborah L.

    2010-01-01

    This study examines the content of press releases from the National Science Foundation (NSF) Science and Technology Centers (STCs) to determine how public information officers (PIOs) presented the outcomes of centers to journalists and the public. A total of 68 press releases were analyzed for type of news covered, visibility of centers and their

  18. College Board AP Scores College Board AP scores for 2012 are released after July 2, 2012. Your 2012 or earlier year scores are not on your UGA record. It is your responsibility to request AP

    E-print Network

    Arnold, Jonathan

    or earlier year scores are not on your UGA record. It is your responsibility to request AP scores and insure that they have properly posted to your academic record. Scores are easily ordered through the Automated Score. If you ordered your scores more than 2 weeks ago but still do not see them on record, there may

  19. 76 FR 6328 - Official Release of the January 2011 AP-42 Method for Estimating Re-Entrained Road Dust From...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-04

    ...applicable range of speeds down to 1 mph from the previous 10 mph, and the incorporation of an...AP-42 method will be, on average, 40% less than the emissions for paved...CAA section 172(c)(3) and 40 CFR...

  20. Press Releases Issued by Supplements Industry Organisations and Non-Industry Organisations in Response to Publication of Clinical Research Findings: A Case-Control Study

    PubMed Central

    Wang, Michael T. M.; Gamble, Greg; Bolland, Mark J.; Grey, Andrew

    2014-01-01

    Background Dietary supplement use is increasing despite lack of evidence of benefits, or evidence of harm. Press releases issued by the supplements industry might contribute to this situation by using spin (strategies to hype or denigrate findings) to distort the results of clinical studies. We assessed press releases issued in response to publication of clinical studies on dietary supplements. Methods and Findings We analyzed 47 supplements industry press releases and 91 non-industry press releases and news stories, generated in response to 46 clinical studies of dietary supplements published between 1/1/2005 and 5/31/2013. The primary outcome was spin content and direction. We also assessed disposition towards use of dietary supplements, reporting of study information, and dissemination of industry press releases. More supplements industry press releases (100%) contained spin than non-industry media documents (55%, P<0.001). Hyping spin scores were higher in industry than non-industry media documents for studies reporting benefit of supplements (median spin score 3.3, 95% CI 1.05.5 vs 0.5, 01.0; P<0.001). Denigratory spin scores were higher in industry than non-industry media documents for studies reporting no effect (6.0, 5.07.0 vs 0, 00; P<0.001) or harm (6.0, 5.57.5 vs 0, 00.5; P<0.001) from a supplement. Industry press releases advocated supplement use in response to >90% of studies that reported no benefit, or harm, of the supplement. Industry press releases less frequently reported study outcomes, sample size, and estimates of effect size than non-industry media documents (all P<0.001), particularly for studies that reported no benefit of supplements. Industry press releases were referenced by 148 news stories on the websites of 6 organizations that inform manufacturers, retailers and consumers of supplements. Conclusions Dietary supplements industry press releases issued in response to clinical research findings are characterized by spin that hypes results that are favourable to supplement use and denigrates results that are not. PMID:24992571

  1. Cav2-Type Calcium Channels Encoded by cac Regulate AP-Independent Neurotransmitter Release at Cholinergic Synapses in Adult Drosophila Brain

    PubMed Central

    Gu, Huaiyu; Jiang, Shaojuan Amy; Campusano, Jorge M.; Iniguez, Jorge; Su, Hailing; Hoang, Andy An; Lavian, Monica; Sun, Xicui; O'Dowd, Diane K.

    2009-01-01

    Voltage-gated calcium channels containing ?1 subunits encoded by Cav2 family genes are critical in regulating release of neurotransmitter at chemical synapses. In Drosophila, cac is the only Cav2-type gene. Cacophony (CAC) channels are localized in motor neuron terminals where they have been shown to mediate evoked, but not AP-independent, release of glutamate at the larval neuromuscular junction (NMJ). Cultured embryonic neurons also express CAC channels, but there is no information about the properties of CAC-mediated currents in adult brain nor how these channels regulate transmission in central neural circuits where fast excitatory synaptic transmission is predominantly cholinergic. Here we report that wild-type neurons cultured from late stage pupal brains and antennal lobe projection neurons (PNs) examined in adult brains, express calcium currents with two components: a slow-inactivating current sensitive to the spider toxin Plectreurys toxin II (PLTXII) and a fast-inactivating PLTXII-resistant component. CAC channels are the major contributors to the slow-inactivating PLTXII-sensitive current based on selective reduction of this component in hypomorphic cac mutants (NT27 and TS3). Another characteristic of cac mutant neurons both in culture and in whole brain recordings is a reduced cholinergic miniature excitatory postsynaptic current frequency that is mimicked in wild-type neurons by acute application of PLTXII. These data demonstrate that cac encoded Cav2-type calcium channels regulate action potential (AP)-independent release of neurotransmitter at excitatory cholinergic synapses in the adult brain, a function not predicted from studies at the larval NMJ. PMID:19004991

  2. PRESS RELEASE / PRESS RELEASE / PRESS RELEASE / PRESS RELEASE / PRESS RELEASE Suplec and Ecole Centrale Paris

    E-print Network

    Paragios, Nikos

    and to finance techno- scientific mobility on the topic of smart cities and smart electrical networks. SMART External Cooperation Window program, CentraleSuplec has obtained a grant for the program SMART - Smart Cities and Smart Grids for Sustainable Development. SMART initiated by Suplec and Ecole Centrale Paris

  3. EVALUATION OF CHEMICAL RELEASES AND WORKER EXPOSURES FROM FILTER PRESS OPERATIONS

    EPA Science Inventory

    The exposures (inhalation and dermal) and releases (air, water, solids, and process streams) associated with the filtration of industrial wastewater sludge from an electronics manufacturing plant were characterized. Chemical releases and worker exposures for a target chemical (t...

  4. EVALUATION OF CHEMICAL RELEASES AND WORKER EXPOSURES FROM FILTER PRESS OPERATIONS

    EPA Science Inventory

    The exposures (inhalation and dermal) and releases (air, water, solids, and process streams) associated with the filtration of industrial wastewater sludge from an electronics manufacturing plant were characterized. hemical releases and worker exposures for a target chemical (tot...

  5. When Medical News Comes from Press ReleasesA Case Study of Pancreatic Cancer and Processed Meat

    PubMed Central

    Taylor, Joseph W.; Long, Marie; Ashley, Elizabeth; Denning, Alex; Gout, Beatrice; Hansen, Kayleigh; Huws, Thomas; Jennings, Leifa; Quinn, Sinead; Sarkies, Patrick; Wojtowicz, Alex; Newton, Philip M.

    2015-01-01

    The media have a key role in communicating advances in medicine to the general public, yet the accuracy of medical journalism is an under-researched area. This project adapted an established monitoring instrument to analyse all identified news reports (n = 312) on a single medical research paper: a meta-analysis published in the British Journal of Cancer which showed a modest link between processed meat consumption and pancreatic cancer. Our most significant finding was that three sources (the journal press release, a story on the BBC News website and a story appearing on the NHS Choices website) appeared to account for the content of over 85% of the news stories which covered the meta analysis, with many of them being verbatim or moderately edited copies and most not citing their source. The quality of these 3 primary sources varied from excellent (NHS Choices, 10 of 11 criteria addressed) to weak (journal press release, 5 of 11 criteria addressed), and this variance was reflected in the accuracy of stories derived from them. Some of the methods used in the original meta-analysis, and a proposed mechanistic explanation for the findings, were challenged in a subsequent commentary also published in the British Journal of Cancer, but this discourse was poorly reflected in the media coverage of the story. PMID:26083640

  6. NATIONAL PRESS RELEASE I PARIS I 29 OCTOBER 2013 Cochlear implants allow adults who have become profoundly deaf to recover the ability to

    E-print Network

    Canet, Lonie

    NATIONAL PRESS RELEASE I PARIS I 29 OCTOBER 2013 Cochlear implants allow adults who have become make it possible to develop diagnostic tools for specific rehabilitation. Cochlear implants role in the success of rehabilitation using a cochlear implant. To support this hypothesis

  7. NATIONAL PRESS RELEASE I PARIS I 30 AUGUST 2013 Brown algae contain phlorotannins, aromatic (phenolic) compounds that are unique in the plant

    E-print Network

    Canet, Lonie

    NATIONAL PRESS RELEASE I PARIS I 30 AUGUST 2013 Brown algae contain phlorotannins, aromatic elucidated the key step in the production of these compounds in Ectocarpus siliculosus, a small brown alga phlorotannins from brown algae for use in industry was a complex process, and the biosynthesis pathways

  8. Press release embargoed until 6.00am Thursday 22 August 2013 Find a 3D fossil the hunt is on!

    E-print Network

    Cambridge, University of

    Press release embargoed until 6.00am Thursday 22 August 2013 Find a 3D fossil the hunt is on Geological Survey that will see fossil types freely available to all. They are also running a competition County Museum. The `type' specimen of a fossil is the one to which all other similar specimens

  9. ?-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between ?6?4 and ?6?2 nicotinic acetylcholine receptors and blocks nicotine-stimulated norepinephrine release

    PubMed Central

    Azam, Layla; Maskos, Uwe; Changeux, Jean-Pierre; Dowell, Cheryl D.; Christensen, Sean; De Biasi, Mariella; McIntosh, J. Michael

    2010-01-01

    ?6* (asterisk indicates the presence of additional subunits) nicotinic acetylcholine receptors (nAChRs) are broadly implicated in catecholamine-dependent disorders that involve attention, motor movement, and nicotine self-administration. Different molecular forms of ?6 nAChRs mediate catecholamine release, but receptor differentiation is greatly hampered by a paucity of subtype selective ligands. ?-Conotoxins are nAChR-targeted peptides used by Conus species to incapacitate prey. We hypothesized that distinct conotoxin-binding kinetics could be exploited to develop a series of selective probes to enable study of native receptor subtypes. Proline6 of ?-conotoxin BuIA was found to be critical for nAChR selectivity; substitution of proline6 with 4-hydroyxproline increased the IC50 by 2800-fold at ?6/?3?2?3 but only by 6-fold at ?6/?3?4 nAChRs (to 1300 and 12 nM, respectively). We used conotoxin probes together with subunit-null mice to interrogate nAChR subtypes that modulate hippocampal norepinephrine release. Release was abolished in ?6-null mutant mice. ?-Conotoxin BuIA[T5A;P6O] partially blocked norepinephrine release in wild-type controls but failed to block release in ?4?/? mice. In contrast, BuIA[T5A;P6O] failed to block dopamine release in the wild-type striatum known to contain ?6?2* nAChRs. BuIA[T5A;P6O] is a novel ligand for distinguishing between closely related ?6* nAChRs; ?6?4* nAChRs modulate norepinephrine release in hippocampus but not dopamine release in striatum.Azam, L., Maskos, U., Changeux, J.-P., Dowell, C. D., Christensen, S., De Biasi, M., McIntosh, J. M. ?-Conotoxin BuIA[T5A;P6O]: a novel ligand that discriminates between ?6?4 and ?6?2 nAChRs and blocks nicotine-stimulated norepinephrine release. PMID:20739611

  10. The U.S. Government's Assistance to the AP's World-Wide Expansion: 1912-1948.

    ERIC Educational Resources Information Center

    Renaud-Komiya, Jean-Luc

    A study of the extent of the diplomatic and commercial assistance provided by the United States government to the Associated Press (AP) from 1912 to 1948 shows AP's manager, Kent Cooper, to be less a champion of the free press than an efficient captain of industry in expanding AP influence across the globe. Early in the twentieth century, British,

  11. Properties of tritium/helium release from hot isostatic pressed beryllium of various trademarks

    NASA Astrophysics Data System (ADS)

    Chekushina, Lyudmila; Dyussambaev, Daulet; Shaimerdenov, Asset; Tsuchiya, Kunihiko; Takeuchi, Tomoaki; Kawamura, Hiroshi; Kulsartov, Timur

    2014-09-01

    Samples of three industrial beryllium trademarks, such as S-200F, S-65H and I-220H are irradiated at about 40 C to the fluence of 1.5 1024 m-2 (E > 1.15 MeV) in reactor WWR-K. On completion of irradiation tests, post irradiation examinations (PIEs) against hardness are carried out, X-ray diffraction (XRD) analysis and scanning electron microscope (SEM) observation. Also He/T2 release properties are measured by the thermal desorption (TDS) method. Relevant obtained values of amounts of the released tritium and helium for all samples of irradiated beryllium are in good agreement, within inaccuracy, comprising 25 3 wppm for helium-4 and 1.3 0.3 wppm for tritium.

  12. PRESS RELEASE FOR IMMEDIATE RELEASE

    E-print Network

    Washington at Seattle, University of

    content of over nine thousand types of food, through the use a laser grid and a camera- equipped mobile creates volumetric representations of food and beverages." When coupled with a robust nutritional database and a powerful back-end server, the DDRS can calculate energy intake on the fly, allowing doc- tors, researchers

  13. Argonne National Laboratory high performance network support of APS experiments

    Microsoft Academic Search

    Martin J. Knot; Robert J. McMahon

    1996-01-01

    Argonne National Laboratory is currently positioned to provide access to high performance regional and national networks. Much of the impetus for this effort is the anticipated needs of the upcoming experimental program at the APS. Some APS collaborative access teams (CATs) are already pressing for network speed improvements and security enhancements. Requirements range from the need for high data rate,

  14. Public Relations Press Release

    E-print Network

    Tbingen, Universitt

    , and the sexual development and fertility of wild animals. This in turn could have a knock-on effect has global food production. As a result, the use of pesticides and their effect on humans, animals animals and the endangerment of species such as amphibians. Can the biochemical effects of pesticides

  15. Media Relations Press Release

    E-print Network

    Fernandez, Eduardo

    of information assurance specialists in four different FAU colleges: the Charles E. Schmidt College of Science Receives National Centers of Academic Excellence in Information Assurance Research Designation BOCA RATON (CCIS) has been designated as a National Center of Academic Excellence in Information Assurance Research

  16. Public Relations Press Release

    E-print Network

    Tbingen, Universitt

    to secure electronic communications and they enable very fast searches of databases. But qubits are also Communications" on 29 August 2013. The researchers aim to link two systems and draw on the advantages of both electronic components for information processing systems," Jzsef Fortgh says. The researchers

  17. Public Relations Press Release

    E-print Network

    Lubich, Christian

    analysis of medieval plague skeletons proves the presence of yersinia pestis bacteria. Collaboration in Canada have been able to confirm that yersinia pestis was behind the great plague. Previous genetic tests in just five years from 1348 to 1353. Until recently it was not certain whether the bacterium yersinia

  18. PRESS RELEASE FROM NEUROPSYCHOPHARMACOLOGY

    E-print Network

    Cai, Long

    TO http://www.nature.com/npp Personality can predict placebo response to pain DOI: 10.1038/NPP.2012- relieving placebo effects in response to a painful experience, according to a study published this week effects in some individuals, particularly when they anticipate that the treatment will reduce their pain

  19. Public Relations Press Release

    E-print Network

    Lubich, Christian

    of medicinal plants uncovered at South African rock shelter An international team of researchers of Sibudu had an intimate knowledge of the plants surrounding the shelter, and were aware of their medicinal construction of plant "bedding" Tbingen, 8.12. 2011 An international team of archaeologists

  20. Public Relations Press Release

    E-print Network

    Tbingen, Universitt

    change and drought in ancient times Tbingen archaeobotanist probes ancient grains to map drought stress if they had had enough water while growing and ripening. Riehl found that periods of drought had had, with settlements finding a variety of ways to deal with the problem. The 1,037 ancient samples were between 12

  1. Public Relations Press Release

    E-print Network

    project adapts bionic structures for use in architecture Tbingen researchers collaborate with Stuttgart," providing total funding of 9.3m. It is coordinated by the University of Stuttgart. "We aim to secure bionic

  2. PRESS RELEASE FROM NEUROPSYCHOPHARMACOLOGY

    E-print Network

    Cai, Long

    companies. Anyone dealing in securities using information contained in this document or in advanced copies.91 The flavour of beer alone may activate a brain region that provokes the urge to become intoxicated, according histories of alcoholism) while the men tasted beer. Although the beer used was alcoholic, the #12;amount

  3. Public Relations Press Release

    E-print Network

    Tbingen, Universitt

    -Georg Rammensee to receive 75,000 for development of revolutionary treatment of kidney cancer Tbingen, 11 of Tbingen. His research has led to two successful clinical trials showing that a kidney cancer patient's own in recognition of Professor Rammensee's breakthroughs in the fields of immunology and anti-cancer vaccines. Hans

  4. PUBLIC INFORMATION PRESS RELEASE

    E-print Network

    Mather, Patrick T.

    anti-theft and tracking applications for their specific cell phone should contact their cell phone: 315-399-8795 Fax: Syracuse Police Recommendations for Cell Phone Owners Syracuse, NY. The Syracuse Police Department is making recommendations to cell phone owners in response to a nationwide increase

  5. PRESS RELEASE / PRESS RELEASE / PRESS RELEASE / PRESS RELEASE Ecole Centrale Paris

    E-print Network

    Paragios, Nikos

    of Marocco assist in the creation, management and development of the Ecole Centrale Casablanca engineering. This project was initiated by Ecole Centrale Paris and the State of Marocco closely with the Centralian

  6. Press Release Corporate Communications

    E-print Network

    Hoffmann, Rolf

    -Darmstadt scientists have found a way to promptly detect hacker attacks on virtual machines. Companies and government's or government-agency's network due to hacker attacks. An entire virtual machine and all of the data stored that recognizes such echo-profiles and triggers protective countermeasures that combat hacker attacks. However, he

  7. Public Relations Press Release

    E-print Network

    Tbingen, Universitt

    on ophthalmic or medical devices to enable them to optimally utilize their vision potential. "Since ZEISS, contrast and color vision, UV protection and visual quality in the twilight, at night or in difficult disturbances, makes it possible to make a "fingerprint" of the human eye and to take this data into account

  8. Public Relations Press Release

    E-print Network

    , the sea and its creatures appear a dull blue color. Evolutionary biologists at the University of Tbingen, the researchers say, is that the fluorescence is a deep red in a part of the spectrum which, it was previously or report. #12;Page2/2 The red-eye wrasse produces deep red biofluorescence to communicate and defend his

  9. Public Relations Press Release

    E-print Network

    Ould Ahmedou, Mohameden

    their studies the team discovered teeth belonging to an entirely new genus and species of fish: The oldest known, as a means to control aquatic plants. Only later did researchers discover that the bighead carp failed to Dr Oldest fossil bighead carp discovered in Vietnam Tbingen, 12 March 2014 During excavations in the Na

  10. Attention that Indicators Receive in the Press

    ERIC Educational Resources Information Center

    Hendriks, Maria; Barzano, Giovanna; Brumana, Emanuela; Cremonesi, Claudia

    2004-01-01

    With the release of each edition of Education at a Glance, the Office for Economic Co-operation and Development (OECD) prepares a press briefing to be used for the international press release and which individual countries in preparing their national press releases can also use. Similarly, the European Union prepares a summary, not for use at the

  11. Protea Biosciences Concludes New Technology License Agreement -Business -Press Releases -msnbc.com http://www.msnbc.msn.com/id/39056126[9/8/2010 3:14:11 PM

    E-print Network

    Vertes, Akos

    believe LAESI technology holds the promise to meet the great need of biologists and medical professionalsProtea Biosciences Concludes New Technology License Agreement - Business - Press Releases - msnbc technology, announced today that the company has concluded an exclusive, worldwide license agreement

  12. 1/9/09 2:14 PMResearchers Pinpoint Spontaneous Gene Mutations Responsible for 10 Percent of Non-Familial Cases of Schizophrenia Page 1 of 3http://cumc.columbia.edu/news/press_releases/gene-mutation-schizophrenia.html

    E-print Network

    -Familial Cases of Schizophrenia Page 1 of 3http://cumc.columbia.edu/news/press_releases/gene-mutation-schizophrenia Gene Mutations Responsible for 10 Percent of Non-Familial Cases of Schizophrenia NEW YORK (May 30, 2008) Scans of the genome of patients with schizophrenia have revealed rare spontaneous copy number mutations

  13. Effects of different enzymatic pre-press maceration treatments on the release of phenols into blackcurrant juice

    Microsoft Academic Search

    Rico Bagger-Jrgensen; Anne S. Meyer

    2004-01-01

    The effects of different pectinolytic enzyme treatments on the release of phenolic compounds from blackcurrant berry mash into juice in experimental blackcurrant juice production were examined. The influence of enzyme dose (00.1% by weight), degree of berry crushing, maceration time, and temperature on the total phenol concentration, the juice yield, and on polysaccharide degradation were evaluated for four commercial, fungal

  14. Neuron,Vol. 14, 163-167,January,1995,Copyright 1995by Cell Press Calcium Release from the Nucleus

    E-print Network

    Clapham, David E.

    ; Bezprozvanny and Ehrlich, 1993). Plant vacuole InsP3Rs differ from mam- malian channels in the bilayer,3,4) form of InsP3, InsP4, and caffeine failed to induce release (Figure 1D). Heparin, an inhibitor of InsP3

  15. Relationship between beta-AP peptide aggregation and microglial activation.

    PubMed

    Casal, Carme; Serratosa, Joan; Tusell, Josep M

    2002-02-22

    We compared the relationship between the state of aggregation of two peptides (beta-AP 25-35 and beta-AP 1-42) and microglial activation. After 7 days at 37 degrees C beta-AP 25-35 was in an amorphous state and did not activate microglial cells. In the same conditions, aggregated beta-AP 1-42 activated these cells and caused changes in microglial ramification, increasing the proliferation index and inducing tumor necrosis factor alpha (TNF alpha) release. Neither peptide induced a release of nitric oxide (NO). As the toxicity of beta-AP peptides in cell culture is associated with the formation of amyloid fibrils, we also examined the toxicity of both peptides in microglial cell cultures and in PC 12 cell cultures. The results suggest that the two beta-AP fragments studied have similar neurotoxic effects but different pro-inflammatory activities. PMID:11844474

  16. Early Telegraphic News Dispatches: The Forerunner of the AP.

    ERIC Educational Resources Information Center

    Schwarzlose, Richard A.

    The origin of the Associated Press (AP) lies in the early cooperative news gathering efforts of the editors of several New York newspapers. As early as May 1846, these editors were "pooling" their energies in response to newly developed modes of communication--the wire and wireless telegraph and the trans-oceanic steamship mail services. The

  17. APS Science 2006.

    SciTech Connect

    Gibson, J. M.; Fenner, R. B.; Long, G.; Borland, M.; Decker, G.

    2007-05-24

    In my five years as the Director of the Advanced Photon Source (APS), I have been fortunate to see major growth in the scientific impact from the APS. This year I am particularly enthusiastic about prospects for our longer-term future. Every scientific instrument must remain at the cutting edge to flourish. Our plans for the next generation of APS--an APS upgrade--got seriously in gear this year with strong encouragement from our users and sponsors. The most promising avenue that has emerged is the energy-recovery linac (ERL) (see article on page xx), for which we are beginning serious R&D. The ERL{at}APS would offer revolutionary performance, especially for x-ray imaging and ultrafast science, while not seriously disrupting the existing user base. I am very proud of our accelerator physics and engineering staff, who not only keep the current APS at the forefront, but were able to greatly impress our international Machine Advisory Committee with the quality of their work on the possible upgrade option (see page xx). As we prepare for long-term major upgrades, our plans to develop and optimize all the sectors at APS in the near future are advancing. Several new beamlines saw first light this year, including a dedicated powder diffraction beamline (11-BM), two instruments for inelastic x-ray scattering at sector 30, and the Center for Nanoscale Materials (CNM) Nanoprobe beamline at sector 26. Our partnership in the first x-ray free-electron laser (LCLS) to be built at Stanford contributes to revolutionary growth in ultrafast science (see page xx), and we are developing a pulse chirping scheme to get ps pulses at sector 7 of the APS within a year or so. In this report, you will find selected highlights of scientific research at the APS from calendar year 2006. The highlighted work covers diverse disciplines, from fundamental to applied science. In the article on page xx you can see the direct impact of APS research on technology. Several new products have emerged from work at the APS, to complement the tremendous output of work in basic science, which often has payoff in technology but over decades rather than years. Highlights in this report also reflect the relevance of APS work to Department of Energy missions, for example a route to more efficient fuel cells (page xx mr-88-073113) addresses the energy challenge, and natural approaches to cleaning up the environment.

  18. AP Central: AP Biology Course Home Page

    NSDL National Science Digital Library

    For students and educators seeking to learn more about the world of biology, this website is the perfect resource. Created by the College Board, this site contains information designed to help individuals prepare for the AP Biology examination. The resources here include a guide to conducting investigative labs in the classroom, an overview of quantitative skills, and several other preparatory items. In the Classroom Resources area, visitors can look over curriculum modules and field trip suggestions among other tools. The "Related Articles" section features pieces such as "Mendel's Legacy," "Gastrulation: Shaping the Embryo," and "DNA and Computers-A Marriage Made in Heaven." The site is rounded out by a series of course overviews crafted specially for AP Biology instructors.

  19. Press Release Release Date: April 20, 2012

    E-print Network

    Russell, Lynn

    to discuss best practices in stress testing. The Dodd-Frank Wall Street Reform and Consumer Protection Act a wide range of topics including methodologies to project losses for mortgages and other consumer

  20. APS Science 2009.

    SciTech Connect

    Gibson, J. M; Mills, D. M.; Gerig, R.

    2010-05-01

    It is my pleasure to introduce the 2009 annual report of the Advanced Photon Source. This was a very good year for us. We operated with high reliability and availability, despite growing problems with obsolete systems, and our users produced a record output of publications. The number of user experiments increased by 14% from 2008 to more than 3600. We congratulate the recipients of the 2009 Nobel Prize in Chemistry-Venkatraman Ramakrishnan (Cambridge Institute for Medical Research), Thomas Steitz (Yale University), and Ada Yonath (Weizmann Institute) - who did a substantial amount of this work at APS beamlines. Thanks to the efforts of our users and staff, and the ongoing counsel of the APS Scientific Advisory Committee, we made major progress in advancing our planning for the upgrade of the APS (APS-U), producing a proposal that was positively reviewed. We hope to get formal approval in 2010 to begin the upgrade. With advocacy from our users and the support of our sponsor, the Office of Basic Energy Sciences in the Department of Energy (DOE) Office of Science, our operating budgets have grown to the level needed to more adequately staff our beamlines. We were also extremely fortunate to have received $7.9 M in American Recovery and Reinvestment Act ('stimulus') funding to acquire new detectors and improve several of our beamlines. The success of the new Linac Coherent Light Source at Stanford, the world's first x-ray free-electron laser, made us particularly proud since the undulators were designed and built by the APS. Among other highlights, we note that more than one-quarter of the 46 Energy Frontier Research Centers, funded competitively across the U.S. in 2009 by the DOE, included the Advanced Photon Source in their proposed work, which shows that synchrotron radiation, and the APS in particular, are central to energy research. While APS research covers everything from fundamental to applied science (reflected by the highlights in this report), the challenge of sustainable energy provides an opportunity for expanded involvement with industrial research. We were privileged to recruit several outstanding new leaders at the APS. Linda Young, from Argonne's Chemical Sciences Division, became the new Director of the X-ray Science Division (XSD). Chris Jacobsen (from Stony Brook University) has been added to Linda's team as an XSD Associate Division Director, joining George Srajer. Alexander (Sasha) Zholents (formerly of Berkeley Lab) became Director of the Accelerator Systems Division. Sasha is the inventor of the short-pulse x-ray scheme that we plan to implement in the APS-U to obtain very high average brightness, broadband, 1-ps x-ray pulses. Walter Lowe (formerly of Howard University) has taken a new position as senior advisor for outreach and development of the user community. Walter's role is to increase the diversity of the user community (with diversity read broadly to include users, institutions, and technical disciplines that are underrepresented at APS). Walter is also leading an effort to increase access for industrial users. I am confident that we have in place a great team to help our users and the APS take fullest advantage of the APS-U opportunity. In planning with users for the proposed APS-U, we focused on the need to study 'real materials under real conditions in real time' on spatial and temporal scales unavailable today. Only by studying materials as they are made-or as they perform-in difficult environments can we solve the grand challenge of higher-performance, sustainable materials for energy and health. The proposed APS-U will improve the brightness of penetrating x-rays produced by the APS over 100 times, and support our efforts in developing state-of-the-art instruments to address these challenges.

  1. The Associated Press Stylebook and Libel Manual. Fully Updated and Revised.

    ERIC Educational Resources Information Center

    Goldstein, Norm, Ed.

    Pointing out that the style of the Associated Press (AP) defines clear writing, this revised edition of the practical and much-used AP stylebook is designed to be an essential handbook for all writers, editors, and students. The stylebook contains over 5000 entries laying out the AP's rules on grammar, spelling, punctuation, and usage. It gives

  2. John Mather Nobel Scholars Named Press Release 2008 July 21 from The Henry Foundation, Inc. http://henry.pha.jhu.edu/

    E-print Network

    PRESS Logistics Carrier (ELC) at NASA's Goddard Space Flight Center. Erin says "working at NASA has been my career at the University of Maryland College Park, who is working with NASA contractor Honeywell Aerospace to design

  3. PRESS RELEASE 26 May 2010

    E-print Network

    Approach EU Directives Certification of high-risk, complex medical devices Performance management softw documents agreed by experts in the field. As w ell as being w idely used w ithin the UK, they are used

  4. PRESS RELEASE Contact: Heather Segale

    E-print Network

    Schladow, S. Geoffrey

    -winning, thought-provoking pieces exploring these and other questions. Preview the new local film Charting (Nestle and the World Bank for example) behind this emerging world water cartel. Flow begs the question sounding the alarm however; it also takes a look at new #12;technologies, practical solutions to water use

  5. CSR Press Release Submitted by

    E-print Network

    and corporate responsibility should be adopted and widely promoted by the Government and the Party in response to orders from China. "The Chinese are buying more German fridges, dryers and cars." "Demand bought a record amount of Japanese government bonds in May, reflecting concerns over the value

  6. PRESS RELEASE RARE FRUIT CONFERENCE

    E-print Network

    Jawitz, James W.

    its conception in 1984. It features visits to botanical gardens, research Botanical Garden this magnificent historic garden was the home of Dr. David Fairchild and is now part of the National Botanical Garden. TREC, University of Florida, Homestead Part of the University of Florida

  7. CSR Press Release Submitted by

    E-print Network

    screening program for household and personal care products sold at Walmart. The partnership also allows and companies working to develop the science to support a sustainability index through The Sustainability

  8. Press Release TU-Darmstadt

    E-print Network

    Haller-Dintelmann, Robert

    with the disease, is difficult, since, by then, the parasites will have penetrated the central nervous system on Molecular Genetics at the TU-Darmstadt's Biology Dept., stated that, "We can now determine, from a few drops of blood, whether someone has been infected with the disease before it breaks out." He and his group have

  9. Press Release 02 December 2013

    E-print Network

    and nanotechnology. The award, which is presented for the first time this year, is sponsored by Tsinghua University and medicine. Charles Lieber is the Mark Hyman Professor of Chemistry at Harvard University. He serves of nanoscience and nanotechnology. His publications have been cited more than 70,000 times, his top ten papers

  10. CSR Press Release Submitted by

    E-print Network

    , and environmental sustainability all contribute to corporate profitability Teradata Corporation Jul 29, 2010 07 aspects, Teradata had an outstanding year. Teradata was named one of the world's most ethical companies profitability, and support a strong and vibrant corporation." Teradata Platform Family: Powerful Analytics

  11. Advancing beyond AP Courses

    ERIC Educational Resources Information Center

    Hammond, Bruce G.

    2009-01-01

    A quiet revolution is picking up steam in the nation's private secondary schools, with broad implications for college admissions and for teaching and learning on both sides of the transition from high school to college. About 50 of the nation's leading college-preparatory schools have opted out of the College Board's Advanced Placement (AP)

  12. Learning about Antiphospholipid Syndrome (APS)

    MedlinePLUS

    ... and links from the National Institutes of Health. Learning About Antiphospholipid Syndrome (APS) What is antiphospholipid syndrome ( ... with APS include : Systemic Vascular Thrombosis While the deep veins of the legs are the most frequent ...

  13. Foreign News Coverage in Three Wire Services: A Study of AP, UPI, and the Nonaligned News Agencies Pool.

    ERIC Educational Resources Information Center

    Kirat, Mohamed; Weaver, David

    A study was conducted to discover (1) how the Associated Press (AP) and United Press International (UPI) wire services and the Nonaligned News Agencies Pool (NANAP) covered international affairs in terms of frequency of stories, countries covered, and kinds of subject matter; (2) differences and similarities in the three agencies' coverage of

  14. APS Science 2007.

    SciTech Connect

    Not Available

    2008-05-30

    This report provides research highlights from the Advanced Photon Source (APS). Although these highlights represent less than 10% of the published work from the APS in 2007, they give a flavor of the diversity and impact of user research at the facility. In the strategic planning the aim is to foster the growth of existing user communities and foresee new areas of research. This coming year finds the APS engaged in putting together, along with the users, a blueprint for the next five years, and making the case for a set of prioritized investments in beamlines, the accelerator, and infrastructure, each of which will be transformational in terms of scientific impact. As this is written plans are being formulated for an important user workshop on October 20-21, 2008, to prioritize strategic plans. The fruit from past investments can be seen in this report. Examples include the creation of a dedicated beamline for x-ray photon correlation spectroscopy at Sector 8, the evolution of dedicated high-energy x-ray scattering beamlines at sectors 1 and 11, a dedicated imaging beamline at Sector 32, and new beamlines for inelastic scattering and powder diffraction. A single-pulse facility has been built in collaboration with Sector 14 (BioCARS) and Phil Anfinrud at the National Institutes of Health, which will offer exceptionally high flux for single-pulse diffraction. The nanoprobe at Sector 26, built and operated jointly by the Argonne Center for Nanoscale Materials and the X-ray Operations and Research (XOR) section of the APS X-ray Science Division, has come on line to define the state of the art in nanoscience.

  15. Thermal Decomposition Characteristics of Orthorhombic Ammonium Perchlorate (o-AP) and an 0-AP/HTPB-Based Propellant

    SciTech Connect

    BEHRENS JR.,RICHARD; MINIER,LEANNA M.G.

    1999-10-25

    A study to characterize the low-temperature reactive processes for o-AP and an AP/HTPB-based propellant (class 1.3) is being conducted in the laboratory using the techniques of simultaneous thermogravimetric modulated beam mass spectrometry (STMBMS) and scanning electron microscopy (SEM). The results presented in this paper are a follow up of the previous work that showed the overall decomposition to be complex and controlled by both physical and chemical processes. The decomposition is characterized by the occurrence of one major event that consumes up to {approx}35% of the AP, depending upon particle size, and leaves behind a porous agglomerate of AP. The major gaseous products released during this event include H{sub 2}O, O{sub 2}, Cl{sub 2}, N{sub 2}O and HCl. The recent efforts provide further insight into the decomposition processes for o-AP. The temporal behaviors of the gas formation rates (GFRs) for the products indicate that the major decomposition event consists of three chemical channels. The first and third channels are affected by the pressure in the reaction cell and occur at the surface or in the gas phase above the surface of the AP particles. The second channel is not affected by pressure and accounts for the solid-phase reactions characteristic of o-AP. The third channel involves the interactions of the decomposition products with the surface of the AP. SEM images of partially decomposed o-AP provide insight to how the morphology changes as the decomposition progresses. A conceptual model has been developed, based upon the STMBMS and SEM results, that provides a basic description of the processes. The thermal decomposition characteristics of the propellant are evaluated from the identities of the products and the temporal behaviors of their GFRs. First, the volatile components in the propellant evolve from the propellant as it is heated. Second, the hot AP (and HClO{sub 4}) at the AP-binder interface oxidize the binder through reactions that preferentially strip the hydrogen from the binder and yield HCl and H{sub 2}O with some oxidation of the carbon from the binder. Third, the o-AP in the propellant decomposes in the same manner as in neat o-AP. Finally, AP-derived gaseous products interact with other ingredients in the propellant.

  16. AP1 function and regulation

    Microsoft Academic Search

    Michael Karin; Zheng-gang Liu; Ebrahim Zandi

    1997-01-01

    AP-1 (activating protein-1) is a collective term referring to dimeric transcription factors composed of Jun, Fos or ATF (activating transcription factor) subunits that bind to a common DNA site, the AP-1-binding site. As the complexity of our knowledge of AP-1 factors has increased, our understanding of their physiological function has decreased. This trend, however, is beginning to be reversed due

  17. Analytical models of CMOS APS

    Microsoft Academic Search

    Victor A. Shilin; Pavel A. Skrylev; A. L. Stempkovsky

    2002-01-01

    The comparison of the CMOS APS and CCD device features has been made. It is expedient to develop high resolution and wide dynamic range systems with the PhCCD and simple systems with CMOS APS, which allows developing camera-on-a-chip. Schematic and layout types of CMOS APS pixel: with 3, 4 transistors per pixel, and with 5 transistors per two pixels have

  18. MIT Press

    NSDL National Science Digital Library

    The editors and staff of The MIT Press, invite you to browse through their on-line catalogues featuring recent books (1993-1994) and current journals. The MIT Press is one of the world's leading scholarly technical publishers, offering texts and monographs in the computational and cognitive sciences, architecture, photography, art and literary theory, economics, environmental science, and linguistics.

  19. 77 FR 53965 - Notice of Open Meetings To Prepare and Release 2012 Annual Report to Congress

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ...strategy, space developments, and intelligence activities and capabilities. China's...November 14, 2012--Official Press Conference to Release Final Report to the Public...20001. The location for the Official Press Conference to release the final Annual...

  20. 76 FR 53717 - Notice of Open Meetings To Prepare and Release 2011 Annual Report to Congress

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-29

    ...strategy, space developments, and intelligence activities and capabilities. China's...November 16, 2011--Official Press Conference to Release Final Report to the Public...Wednesday, November 16: Official Press Conference to Release Final Report to...

  1. 77 FR 43662 - Notice of Open Meetings To Prepare and Release 2012 Annual Report to Congress

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-25

    ...strategy, space developments, and intelligence activities and capabilities. China's...November 14, 2012--Official Press Conference to Release Final Report to the Public...20001. The location for the Official Press Conference to release the final Annual...

  2. AP Photo/Andy Fowle Buy AP Photo Reprints

    E-print Network

    Hartemink, Alexander

    AP Photo/Andy Fowle Buy AP Photo Reprints Nov 30, 6:49 AM EST Duke Scientists Map 'Silenced Genes of their babies. The feed affected chemical signals that control how hard a certain gene worked, determining when the babies had yellow coats like mom or brown ones. Top Stories #12;Corrections | Contact Us | Letters

  3. ANL/APS/TB-5 Functional Description of APS Beamline

    E-print Network

    Kemner, Ken

    ANL/APS/TB-5 Functional Description of APS Beamline Front Ends by Tuncer Kuzay February 1993 Advanced Photon Source & Argonne National Laboratory, Argonne, Illinois 60439 o operated by The University of Chicago for the United States Department of Energy under Contract W-31-1 09-Eng-38 #12;Argonne National

  4. Michael Clay, MD AP-2 Resident

    E-print Network

    Bogyo, Matthew

    Michael Clay, MD AP-2 Resident Daniel Cloetingh, MD AP-1 Resident Eli Goodman, MD CP-1 Resident Daniel Green, MD AP-1 Resident Dexter Hadley, MD, PhD CP-1 Resident Ryanne Brown, MD AP-1 Resident Sara Bakhtary, MD CP-1 Resident Aharon (Ronnie) Freud, MD, PhD CP-2 Resident Alana Frost Shain, MD AP-2 Resident

  5. AP-42 REVISION: COKE OVENS

    EPA Science Inventory

    The document "Compilation of Air Pollutant Emission Factors" (AP-42) has been published by the U. S. Environmental Protection Agency (EPA) since 1972. Supplements to AP-42 have been routinely published to add new emission source categories and to update existing emission factor...

  6. A location-aware rogue AP detection system based on wireless packet sniffing of sensor APs

    Microsoft Academic Search

    Kuo-Fong Kao; Tau-Heng Yeo; Wai-Shuen Yong; Hui-Hsuan Chen

    2011-01-01

    For easy installation and increasing the use of wireless LAN access points (AP), an unauthorized AP can be quickly plugged into the LANs of most organizations. Unauthorized APs are also termed rogue APs, and can seriously threaten network security. Detecting the existence of rogue APs has become an important research topic. A rogue AP should work by broadcasting wireless packets.

  7. The Associated Press Stylebook and Libel Manual. Fully Revised and Updated.

    ERIC Educational Resources Information Center

    Goldstein, Norm, Ed.

    Noting that more people write for The Associated Press (AP) than for any single newspaper in the world and that its style defines clear writing, this book presents more than 5000 entries that present AP's rules on grammar, spelling, punctuation and usage, with extra sections about reporting business and sports. The book, considered essential for

  8. arXiv:astroph/0004411 ApJ, in press

    E-print Network

    Rauch, Kevin P.

    framedragging (labeled here as ``Kerr'') effects on the spacetime metric. Previously, Chen & Shaham static field and metric approximations may be inadequate. In this paper we model the effects of rapid (1989) noticed the above effects. They modeled the neutron star as a Kerr black hole, and computed

  9. APS controls overview

    SciTech Connect

    NONE

    1996-02-01

    The APS accelerator control system described in this report is a distributed system consisting of operator interfaces, a network, and interfaces to hardware. The operator interface is a UNIX-based workstation with an X-windows graphical user interface. The workstation may be located at any point on the facility network and maintain full functionality. The user has the ability to generate and alter control displays and to access the alarm handler, the archiver, interactive control programs, custom code, and other tools. The TCP/EP networking protocol has been selected as the underlying protocol for the control system network. TCP/EP is a commercial standard and readily available from network hardware vendors. Its implementation is independent of the particular network medium selected to implement the controls network. In the development environment copper Ethernet is the network medium; however, in the actual implementation a fiber-based system using hub technology will be utilized. The function of the network is to provide a generalized communication path between the host computers, operator workstations, input/output crates, and other hardware that comprise the control system.

  10. Lost City News Release

    NSDL National Science Digital Library

    Office of Legislative and Public Affairs

    This press release from the National Science Foundation provides an overview of the 2003 expedition to the Lost City Hydrothermal Field at the Atlantis Massif. It briefly describes the expedition, features of the Lost City, research results and implications for future discoveries. Photos and images accompany the text.

  11. Low Earth orbit assessment of proton anisotropy using AP8 and AP9 trapped proton models.

    PubMed

    Badavi, Francis F; Walker, Steven A; Santos Koos, Lindsey M

    2015-04-01

    The completion of the International Space Station (ISS) in 2011 has provided the space research community with an ideal evaluation and testing facility for future long duration human activities in space. Ionized and secondary neutral particles radiation measurements inside ISS form the ideal tool for validation of radiation environmental models, nuclear reaction cross sections and transport codes. Studies using thermo-luminescent detectors (TLD), tissue equivalent proportional counter (TPEC), and computer aided design (CAD) models of early ISS configurations confirmed that, as input, computational dosimetry at low Earth orbit (LEO) requires an environmental model with directional (anisotropic) capability to properly describe the exposure of trapped protons within ISS. At LEO, ISS encounters exposure from trapped electrons, protons and geomagnetically attenuated galactic cosmic rays (GCR). For short duration studies at LEO, one can ignore trapped electrons and ever present GCR exposure contributions during quiet times. However, within the trapped proton field, a challenge arises from properly estimating the amount of proton exposure acquired. There exist a number of models to define the intensity of trapped particles. Among the established trapped models are the historic AE8/AP8, dating back to the 1980s and the recently released AE9/AP9/SPM. Since at LEO electrons have minimal exposure contribution to ISS, this work ignores the AE8 and AE9 components of the models and couples a measurement derived anisotropic trapped proton formalism to omnidirectional output from the AP8 and AP9 models, allowing the assessment of the differences between the two proton models. The assessment is done at a target point within the ISS-11A configuration (circa 2003) crew quarter (CQ) of Russian Zvezda service module (SM), during its ascending and descending nodes passes through the south Atlantic anomaly (SAA). The anisotropic formalism incorporates the contributions of proton narrow pitch angle (PA) and east-west (EW) effects. Within SAA, the EW anisotropy results in different level of exposure to each side of the ISS Zvezda SM, allowing angular evaluation of the anisotropic proton spectrum. While the combined magnitude of PA and EW effects at LEO depends on a multitude of factors such as trapped proton energy, orientation and altitude of the spacecraft along the velocity vector, this paper draws quantitative conclusions on the combined anisotropic magnitude differences within ISS SM target point between AP8 and AP9 models. PMID:26177846

  12. Multicomponent Implant Releasing Dexamethasone

    NASA Astrophysics Data System (ADS)

    Nikkola, L.; Vapalahti, K.; Ashammakhi, N.

    2008-02-01

    Several inflammatory conditions are usually treated with corticosteroids. There are various problems like side effects with traditional applications of steroids, e.g. topical, or systemic routes. Local drug delivery systems have been studied and developed to gain more efficient administration with fewer side effects. Earlier, we reported on developing Dexamethasone (DX) releasing biodegradable fibers. However, their drug release properties were not satisfactory in terms of onset of drug release. Thus, we assessed the development of multicomponent (MC) implant to enhance earlier drug release from such biodegradable fibers. Poly (lactide-co-glycolide) (PLGA) and 2 wt-% and 8 wt-% DX were compounded and extruded with twin-screw extruder to form of fibers. Some of the fibers were sterilized to obtain a change in drug release properties. Four different fiber classes were studied: 2 wt-%, 8 wt-%, sterilized 2 wt-%, and sterilized 8 wt-%. 34 different DX-releasing fibers were then heat-pressed to form one multicomponent rod. Half of the rods where sterilized. Drug release was measured from initial fibers and multicomponent rods using a UV/VIS spectrometer. Shear strength and changes in viscosity were also measured. Drug release studies showed that drug release commenced earlier from multicomponent rods than from component fibers. Drug release from multicomponent rods lasted from day 30 to day 70. The release period of sterilized rods extended from day 23 to day 57. When compared to the original component fibers, the drug release from MC rods commenced earlier. The initial shear strength of MC rods was 135 MPa and decreased to 105 MPa during four weeks of immersion in phosphate buffer solution. Accordingly, heat pressing has a positive effect on drug release. After four weeks in hydrolysis, no disintegration was observed.

  13. Equine Infectious Anemia Virus Gag Polyprotein Late Domain Specifically Recruits Cellular AP2 Adapter Protein Complexes during Virion Assembly

    Microsoft Academic Search

    BRIDGET A. PUFFER; S. C. WATKINS; RONALD C. MONTELARO

    1998-01-01

    We have identified an interaction between the equine infectious anemia virus (EIAV) late assembly domain and the cellular AP-2 clathrin-associated adapter protein complex. A YXXL motif within the EIAV Gag late assembly domain was previously characterized as a sequence critical for release of assembling virions. We now show that this YXXL sequence interacts in vitro with the AP-50 subunit of

  14. ANL/APS/LS-314 On-Axis Brilliance and Power of In-Vacuum Undulators for

    E-print Network

    Kemner, Ken

    ANL/APS/LS-314 On-Axis Brilliance and Power of In-Vacuum Undulators for the Advanced Photon Source as cleared document ANL/APS/LS-314; updated in ICMS. Rev. 0a, June 17, 2009: ICMS Initial Release (minor

  15. Attacks on the Press in 2001

    NSDL National Science Digital Library

    2002-01-01

    Released by the Committee to Protect Journalists (CPJ), a nonpartisan, nonprofit organization established to "monitor abuses against the press and promote press freedom around the world," Attacks on the Press 2001 documents the deaths, imprisonment, and abuses of journalists around the world within the past year. Prefaced by CPJ board member Anne Garrels with an introduction by CPJ's executive director Ann Cooper, the report contains an overview of media attacks arranged by country, along with three special press freedom reports on Syria, Burma, and Colombia. In addition, the report contains a Ten Worst Enemies of the Press section that focuses attention on individual leaders responsible for the world's worst abuses against the media. Topping the list are Supreme Leader Ayatollah Ali Khamenei of Iran, President Jiang Zemin of China, and Liberian president Charles Taylor.

  16. AP Chemistry Course Home Page

    NSDL National Science Digital Library

    For people with a penchant for benzene rings and other topics, the AP Chemistry Course site is a great resource. Designed for both educators and students, the site contains resources for teaching to the AP exam as well as a wealth of other items. Interested parties should explore the Classroom Resources where they will find seven different lab activities, such as "Misconceptions and Issues in Quantum Theory" and "Women Scientists of the Manhattan Project.? Additionally, the site features Other Core Resources which includes an open forum for educators along with some basic overviews for crafting a one-semester course in chemistry.

  17. AP Human Geography and Success on the AP Test

    ERIC Educational Resources Information Center

    Roncone, John; Newhalfen, Nate

    2013-01-01

    Classroom projects that explore culture and globalization enhance the curriculum and help students see how geography directly connects to their lives. These authors contend that a project-based approach can supplement the teaching of an AP Human Geography course, and visualize this course as an essential tool for students to truly understand how

  18. ASSESSING CHEMICAL RELEASES AND WORKER EXPOSURES FROM A FILTERPRESS

    EPA Science Inventory

    Chemical releases and worker exposures associated with the filtration of an industrial wastewater sludge were characterized. The filter was a recessed chamber filter press with an open filtrate discharge system. Chemical releases and worker exposures for a selected chemical were ...

  19. APS undergraduate brainstorming summit report

    NSDL National Science Digital Library

    PhD Robert G. Carroll (East Carolina State University Department of Physiology)

    2007-12-09

    IN 2004, the Education Committee was charged with seeking additional strategies to increase the exposure of undergraduate students to physiology studies and careers. Following a reaffirmation of this charge in the 2006 strategic plan, the American Physiological Society (APS) hosted an undergraduate brainstorming summit in late September of 2006.

  20. APS beamline standard components handbook

    SciTech Connect

    Kuzay, T.M.

    1992-01-01

    It is clear that most Advanced Photon Source (APS) Collaborative Access Team (CAT) members would like to concentrate on designing specialized equipment related to their scientific programs rather than on routine or standard beamline components. Thus, an effort is in progress at the APS to identify standard and modular components of APS beamlines. Identifying standard components is a nontrivial task because these components should support diverse beamline objectives. To assist with this effort, the APS has obtained advice and help from a Beamline Standardization and Modularization Committee consisting of experts in beamline design, construction, and operation. The staff of the Experimental Facilities Division identified various components thought to be standard items for beamlines, regardless of the specific scientific objective of a particular beamline. A generic beamline layout formed the basis for this identification. This layout is based on a double-crystal monochromator as the first optical element, with the possibility of other elements to follow. Pre-engineering designs were then made of the identified standard components. The Beamline Standardization and Modularization Committee has reviewed these designs and provided very useful input regarding the specifications of these components. We realize that there will be other configurations that may require special or modified components. This Handbook in its current version (1.1) contains descriptions, specifications, and pre-engineering design drawings of these standard components. In the future, the APS plans to add engineering drawings of identified standard beamline components. Use of standard components should result in major cost reductions for CATs in the areas of beamline design and construction.

  1. Letting The NASA Press Engine Work For You

    NASA Technical Reports Server (NTRS)

    Weaver, Kimberly

    2006-01-01

    You have an amazing result based on NASA data or a NASA Mission; you have written your seminal paper and submitted it to your favorite journal. You believe it has press potential and maybe you've even gotten help from your PR folks in writing a press release. Now you would really like NASA to issue this as a press release. But how do you do that? This presentation will illustrate the steps required to engage NASA in helping promote your story. What are NASA's requirements for newsworthiness? Should your news be released as a web feature story or in the local media? Does your news rise to the level of a full-blown press conference or will it be a media teleconference? How do you obtain approval for a NASA press event? Once your result is scheduled to be issued as a press release, how can you improve your chances of getting the best possible coverage for your story? I will discuss the NASA press process and suggest how to consider factors like timing, working with your collaborating institutions in an efficient way, and not letting the cat out of the bag until the press event.

  2. Agenda Building Role of News Releases in Corporate Takeovers.

    ERIC Educational Resources Information Center

    Ohl, Coral M.; And Others

    1995-01-01

    Examines how particular characteristics of two companies' press releases, generated during a hostile takeover attempt, influenced the media's news decisions. Finds that press releases from Prime Computer were associated with newspaper articles that were longer, more favorable to its point of view, and contained the same lead message points as

  3. Update on autoimmune polyendocrine syndromes (APS)

    Microsoft Academic Search

    Corrado Betterle; Renato Zanchetta

    2003-01-01

    Autoimmune Polyendocrine Syndromes (APS) were initially defined as a multiple endocrine gland insufficiency associated to an autoimmune disease in a patient. Neufeld & Blizzard (1980) suggested a classification of APS, based on clinical criteria only, describing four main types. APS-1 is characterized by presence of chronic candidiasis, chronic hypoparathyroidism, Addison's disease. It is a very rare syndrome in- teresting young

  4. Preparing Students for the AP Psychology Exam

    ERIC Educational Resources Information Center

    Whitlock, Kristin

    2013-01-01

    The Advanced Placement Psychology exam is one of the fastest growing exams offered by the College Board. The average percent of change in the number of students taking this exam over the past five years is 12.4%. With 238,962 students taking the exam in 2013, the AP Psychology exam is the sixth largest exam, surpassing AP Biology and AP World

  5. Graphing Calculators' Impact on AP Biology.

    ERIC Educational Resources Information Center

    Lukens, Jeffrey D.; Feinstein, Sheryl

    The central premise of this study was that the use of graphing calculator technology helped improve students' achievement in upper level biology courses. The populations studied included high school students in a block course entitled "AP Biology/AP Calculus" and students in a traditional AP Biology course. There appears to be a positive effect on

  6. Optimum design of CMOS APS imagers

    Microsoft Academic Search

    Victor A. Shilin; Pavel A. Skrylev; Alexander L. Stempkovsky

    2003-01-01

    The main problem for CMOS active pixel sensors (APS) design is its fill factor and photosensitivity improvement. Using developed CMOS APS models we have solved this problem as mathematical optimization task. The fill factor is the aim function. The limits are: time delays, signal-to-noise ratio, horizontal and vertical MTFs, pixel sizes, and project rules. The simulation results for APS based

  7. M ap Info ... SQL Server " , ,,oe , , ,

    E-print Network

    Li, Xiang

    M ap Info ... SQL Server " , ,,oe , , , (~' G IS ,--^-- , ~' 210093^ Delphi ` M ap Info ... SQL Server ~,,-- ,,... : G IS; ... ; ,,-- ; ,, ;M ap Info; SQL Server --..." : P208 ~OE : A ~" : 1000- 3177(2001) 61- 0026- 0030 1 -- (G

  8. The APS control system network

    Microsoft Academic Search

    K. V. Sidorowicz; W. P. McDowell

    1995-01-01

    The APS accelerator control system is a distributed system consisting of operator interfaces, a network, and computer-controlled interfaces to hardware. This implementation of a control system has come to be called the {open_quotes}Standard Model.{close_quotes} The operator interface is a UNDC-based workstation with an X-windows graphical user interface. The workstation may be located at any point on the facility network and

  9. APS Presents Awards at 2008 ABRCMS Conference

    NSDL National Science Digital Library

    2009-02-01

    This is an article in The Physiologist. APS Presents Awards at Annual ABRCMS Conference APS/NIDDK Minority Travel Fellows Attend the 2008 APS Intersociety Meeting: The Integrative Biology of Exercise Education Special Sessions at Experimental Biology 2009 -------------------------------------------------------------------------------- APS Presents Awards at Annual ABRCMS Conference The APS presented awards to minority undergraduate researchers and was a major conference sponsor at the Annual Biomedical Research Conference for Minority Students (ABRCMS) at Disney?s Coronado Springs Resort, Lake Buena Vista, FL from November 5-9, 2008.

  10. Dynamics of intracellular clathrin/AP1- and clathrin/AP3-containing carriers.

    PubMed

    Kural, Comert; Tacheva-Grigorova, Silvia K; Boulant, Steeve; Cocucci, Emanuele; Baust, Thorsten; Duarte, Delfim; Kirchhausen, Tom

    2012-11-29

    Clathrin/AP1- and clathrin/AP3-coated vesicular carriers originate from endosomes and the trans-Golgi network. Here, we report the real-time visualization of these structures in living cells reliably tracked by rapid, three-dimensional imaging with the use of a spinning-disk confocal microscope. We imaged relatively sparse, diffraction-limited, fluorescent objects containing chimeric fluorescent protein (clathrin light chain, ? adaptor subunits, or dynamin2) with a spatial precision of up to ~30 nm and a temporal resolution of ~1 s. The dynamic characteristics of the intracellular clathrin/AP1 and clathrin/AP3 carriers are similar to those of endocytic clathrin/AP2 pits and vesicles; the clathrin/AP1 coats are, on average, slightly shorter-lived than their AP2 and AP3 counterparts. We confirmed that although dynamin2 is recruited as a burst to clathrin/AP2 pits immediately before their budding from the plasma membrane, we found no evidence supporting a similar association of dynamin2 with clathrin/AP1 or clathrin/AP3 carriers at any stage during their lifetime. We found no effects of chemical inhibitors of dynamin function or the K44A dominant-negative mutant of dynamin on AP1 and AP3 dynamics. This observation suggests that an alternative budding mechanism, yet to be discovered, is responsible for the scission step of clathrin/AP1 and clathrin/AP3 carriers. PMID:23103167

  11. recent press releases MIT scientists theorize

    E-print Network

    Yanik, Mehmet Fatih

    @mit.edu call: 617-253-1682 written by: Anne Trafton, MIT News Office email print share Zebrafish embryos, seen. -- One of the most commonly studied laboratory animals is the zebrafish -- a tiny fish with transparent several minutes to visually examine each larva. This has kept researchers from using the fish

  12. About Global Forest Watch Press Release

    E-print Network

    in Indonesia, resulting in a doubling of the country's deforestation rates in the late 1990s, according. "Deforestation on this scale, at this speed, is unprecedented," said Emily Matthews, co-author of the report concludes that the doubling of deforestation rates in Indonesia is largely the result of a corrupt political

  13. Press Release Date: Friday 22nd

    E-print Network

    Stell, John

    copies of his new book `Self Belief: The Vision', the book sees Jamal setting his readers various challenges, all designed to improve their self belief and help them make their dreams a reality at different music-based events. Over the last five years Jamal has grown his youth broadcasting channel, SB

  14. PRESS RELEASE February 28, 2012 COLUMBIA UNIVERSITY

    E-print Network

    Qian, Ning

    scholars to promote the knowledge of those areas of Italian learning which have contributed so greatly UNIVERSITY The Italian Academy for Advanced Studies in America Compagnia di San Paolo Italian Academy Distinguished Visiting Professor Wednesday, March 21, 2012 6:00 pm

  15. Press Release Date: Monday 20 January 2014

    E-print Network

    Stell, John

    for students. Both current and past students are taking part in this year's festival. Leeds College of Art. Leeds College of Art's graphic design Programme Leader Amber Smith is the founder and organiser of Leeds and production within Yorkshire' says Smith. `Leeds has changed a lot in recent years with so many independent

  16. press release Edward Elgar Publishing Inc.

    E-print Network

    Nagurney, Anna

    , R. Ramesh, B. Rustem, R. Settergren,K.D. Simsek, L.Tesfatsion,A.B.Whinston, D. Zhang December 2003 has had a long tradition in such fields as engineering, operations research, management science and computer science. More recently, the disciplines of finance and economics have come to be rich

  17. HangarBicocca, Milan Press Release

    E-print Network

    and Lindstrand Technologies, a leading company in the research and production of aerostatic materials the limitations of physics through the experimentation of materials and techniques never used before. The outcome corporate history ever open to innovation on the constant dialectic between the rigor of technological

  18. Mars Exploration Rover Mission: Press Release Images

    NSDL National Science Digital Library

    The public can now view the amazing, newly collected images of Mars thanks to this Mars Exploration Rover Mission website. The first images, made available on January 4, 2004, are black and white pictorials of the rover on the surface of Mars. On January 6, 2004, this website provided users with the first color images of Mars. Alongside each image, the NASA team has provided users with straightforward explanations. Everyone will enjoy these images of Spirit's descent, Mars' wind-polished rocks, the Martian Horizon, and much more.

  19. Press Release For the 1st

    E-print Network

    Chan, Hue Sun

    'ORAL-UNESCO Awards For Women in Science Montreal, November 10th 2008 In conjunction with World Science Day on November 10th , 2008, the jury of the L'ORAL-UNESCO Awards For Women in Science announces the names Awards. Created in 1998, the L'ORAL-UNESCO Awards For Women in Science were established as the first

  20. MPA CMap Press Release January 24, 2013

    E-print Network

    Tipple, Brett

    site. The course is part of the University of Utah Master of Public Administration (MPA) program motivated to create something useful for the nonprofits in our state, and the concept maps they created the basics of forming a nonprofit organization, is publicly available at the following link: https

  1. Press Release For immediate release Anxious pregnant women are more

    E-print Network

    Bristol, University of

    likely to have a child who later develops asthma than mothers with a lower level of anxiety. The research of their child going on to develop asthma, according to the latest research from Children of the 90s. Asthma, affects around one child in every 10 and, although the causes of this respiratory condition are not yet

  2. ELECTROCHEMICAL CORROSION TESTING OF TANKS 241-AN-102 & 241-AP-107 & 241-AP-108 IN SUPPORT OF ULTRASONIC TESTING

    SciTech Connect

    WYRWAS RB; DUNCAN JB

    2008-11-20

    This report presents the results of the corrosion rates that were measured using electrochemical methods for tanks 241-AN-102 (AN-102), 241-AP-107 (AP 107), and 241-AP-108 (AP-108) performed under test plant RPP-PLAN-38215. The steel used as materials of construction for AN and AP tank farms was A537 Class 1. Test coupons of A537 Class 1 carbon steel were used for corrosion testing in the AN-107, AP-107, and AP-108 tank waste. Supernate will be tested from AN-102, AP-107, and Ap-108. Saltcake testing was performed on AP-108 only.

  3. AP Trends: Tests Soar, Scores Slip--Gaps between Groups Spur Equity Concerns

    ERIC Educational Resources Information Center

    Cech, Scott J.

    2008-01-01

    More students are taking Advanced Placement tests, but the proportion of tests receiving what is deemed a passing score has dipped, and the mean score is down for the fourth year in a row. Data released here this week by the New York City-based nonprofit organization that owns the AP brand shows that a greater-than-ever proportion of students

  4. The Global University Press

    ERIC Educational Resources Information Center

    Dougherty, Peter J.

    2012-01-01

    The modern world's understanding of American university press has long been shaped by university-press books. American university-press books are good international advertisements for the universities whose logos grace their spines. The growth of transnational scholarship and the expansion of digital communications networks are converging in ways

  5. Advanced APS impacts on vehicle payloads

    NASA Technical Reports Server (NTRS)

    Schneider, Steven J.; Reed, Brian D.

    1989-01-01

    Advanced auxiliary propulsion system (APS) technology has the potential to both, increase the payload capability of earth-to-orbit (ETO) vehicles by reducing APS propellant mass, and simplify ground operations and logistics by reducing the number of fluids on the vehicle and eliminating toxic, corrosive propellants. The impact of integrated cryogenic APS on vehicle payloads is addressed. In this system, launch propulsion system residuals are scavenged from integral launch propulsion tanks for use in the APS. Sufficient propellant is preloaded into the APS to return to earth with margin and noncomplete scavenging assumed. No propellant conditioning is required by the APS, but ambient heat soak is accommodated. High temperature rocket materials enable the use of the unconditioned hydrogen/oxygen in the APS and are estimated to give APS rockets specific impulse of up to about 444 sec. The payload benefits are quantified and compared with an uprated monomethylhydrazine/nitrogen tetroxide system in a conservative fashion, by assuming a 25.5 percent weight growth for the hydrogen/oxygen system and a 0 percent weight growth for the uprated system. The combination of scavenging and high performance gives payload impacts which are highly mission specific. A payload benefit of 861 kg (1898 lbm) was estimated for a Space Station Freedom rendezvous mission and 2099 kg (4626 lbm) for a sortie mission, with payload impacts varying with the amount of launch propulsion residual propellants. Missions without liquid propellant scavenging were estimated to have payload penalties, however, operational benefits were still possible.

  6. AP-42 ADDITIONS AND REVISIONS - WILDLAND FIRES

    EPA Science Inventory

    This project is aimed at consolidating, selecting, and disseminating the most appropriate data and methods for estimating air emissions from wildfires and prescribed burns. The product will replace a current section of AP-42, but may not take the precise form of an AP-42 secti...

  7. Advanced APS impacts on vehicle payloads

    NASA Astrophysics Data System (ADS)

    Schneider, Steven J.; Reed, Brian D.

    1989-04-01

    Advanced auxiliary propulsion system (APS) technology has the potential to both, increase the payload capability of earth-to-orbit (ETO) vehicles by reducing APS propellant mass, and simplify ground operations and logistics by reducing the number of fluids on the vehicle and eliminating toxic, corrosive propellants. The impact of integrated cryogenic APS on vehicle payloads is addressed. In this system, launch propulsion system residuals are scavenged from integral launch propulsion tanks for use in the APS. Sufficient propellant is preloaded into the APS to return to earth with margin and noncomplete scavenging assumed. No propellant conditioning is required by the APS, but ambient heat soak is accommodated. High temperature rocket materials enable the use of the unconditioned hydrogen/oxygen in the APS and are estimated to give APS rockets specific impulse of up to about 444 sec. The payload benefits are quantified and compared with an uprated monomethylhydrazine/nitrogen tetroxide system in a conservative fashion, by assuming a 25.5 percent weight growth for the hydrogen/oxygen system and a 0 percent weight growth for the uprated system. The combination of scavenging and high performance gives payload impacts which are highly mission specific. A payload benefit of 861 kg (1898 lbm) was estimated for a Space Station Freedom rendezvous mission and 2099 kg (4626 lbm) for a sortie mission, with payload impacts varying with the amount of launch propulsion residual propellants. Missions without liquid propellant scavenging were estimated to have payload penalties, however, operational benefits were still possible.

  8. Update on autoimmune polyendocrine syndromes (APS).

    PubMed

    Betterle, Corrado; Zanchetta, Renato

    2003-04-01

    Autoimmune Polyendocrine Syndromes (APS) were initially defined as a multiple endocrine gland insufficiency associated to an autoimmune disease in a patient. Neufeld & Blizzard (1980) suggested a classification of APS, based on clinical criteria only, describing four main types. APS-1 is characterized by presence of chronic candidiasis, chronic hypoparathyroidism, Addison's disease. It is a very rare syndrome interesting young subjects correlating to different mutations of AIRE (AutoImmuneRegulator) gene on chromosome 21. APS-2 is characterized by presence of Addison's disease (always present), autoimmune thyroid diseases and/or type 1 diabetes mellitus. It is a rare syndrome interesting particularly adult females and associated to a genetic pattern of HLA DR3/DR4. Autoimmune thyroid diseases associated to other autoimmune diseases (excluding Addison's disease and/or hypoparathyroidism), are the main characteristics of APS-3. The different clinical combinations of autoimmune diseases not included in the previous groups are characteristics of APS-4. In this paper criteria for defining a disease as autoimmune are presented. Furthermore, the classification, epidemiology, pathogenesis, genetic, animal models, clinical features, laboratory's tests, imaging, therapy, recent progresses in understanding the APS and a detailed analysis of large group of our patients affected by different types of APS are proposed and discussed. PMID:12817789

  9. Advanced Placement Program: What's Changing in AP

    NSDL National Science Digital Library

    2012-12-26

    The AP Program has recently redesigned several courses in science, history, and world languages in an effort to stay strongly aligned with college credit policies and to prepare students for future learning and career pursuit. This website focuses on informing AP teachers about what's changing in AP, from course scope to exam preparation. The AP Chemistry revision will take effect in Fall, 2013. The change that will impact physics teachers most directly is the replacement of AP Physics B with two new year-long courses: AP Physics 1 Algebra-Based and AP Physics 2 Algebra-Based (scheduled to be deployed Fall, 2014). The changes to each course were guided by National Research Council and National Science Foundation recommendations, following several years of collaborations among university educators and master AP teachers. Especially noteworthy are the changes that integrate science practice as an essential component of the curriculum, along with statements that pair the essential knowledge (learning goal) to the appropriate science practice and articulate specific performance objectives.

  10. ISSN 1931-5015 APS SCIENCE 2013

    E-print Network

    Kemner, Ken

    science 2013 TABLE OF CONTENTS iv. APS orgAnizAtion chArt 1 the AdvAnced Photon Source FAcility At ArgonneANL-14/04 ISSN 1931-5015 May 2014 APS SCIENCE 2013 RESEARCH AND ENGINEERING HIGHLIGHTS FROM of Science, Office of Basic Energy Sciences, under Contract No. DE-ACO2-06CH11357. About Argonne National

  11. RESEARCH PUBLICATIONS A.P.S. Selvadurai

    E-print Network

    Barthelat, Francois

    nd Canadian Geotechnical Conference, Quebec City, pp.2.154-2.172. 9. Selvadurai, A.P.S., Bauer, G Conference, Quebec City, pp.2.211-2.224. #12;10. Selvadurai, A.P.S. (1979) The flexure of a uniformly loaded

  12. AP Courses Get Audited for Quality

    ERIC Educational Resources Information Center

    Ashford, Ellie

    2007-01-01

    As the college admissions process has gotten much more competitive, the number of high school students taking Advanced Placement (AP) courses has soared. At the same time, policymakers and education leaders seek to get more minorities and students not on the college track to sign up for AP and other rigorous classes. But as high schools have

  13. ANL/APS/LS-332 August 2012

    E-print Network

    Kemner, Ken

    ANL/APS/LS-332 August 2012 A Compact Soft X-ray Free-Electron Laser Facility based on a Dielectric, and perform publicly and display publicly, by or on behalf of the Government. #12;ANL/APS/LS-332 A COMPACT

  14. Pharmaceutical development, quality control, stability and compatibility of a parenteral lyophilized formulation of the investigational polymer-conjugated platinum antineoplastic agent AP5346.

    PubMed

    Van der Schoot, S C; Nuijen, B; Sood, P; Thurmond, K B; Stewart, D R; Rice, J R; Beijnen, J H

    2006-10-01

    AP5346 is a low molecular weight polymer-conjugated platinum antineoplastic agent. The lyophilized drug product has completed a phase I clinical trial. In order to guarantee a constant quality of AP5346 pharmaceutical products, quality control and analysis of the drug substance and final product were performed. The identity of AP5346 was confirmed using 1H NMR, 195Pt NMR and IR spectroscopy. Furthermore, the free platinum content, platinum release characteristics, molecular size and size distribution were established. With the selected analytical techniques, AP5346 could be distinguished very well from its polymeric analogues, such as AP5280 and AP5279. Stability experiments revealed that AP5346 final product is stable for 12 months at 5 degrees C, in the dark. For administration to patients, AP5346 final product is reconstituted with 5% w/v dextrose and diluted in infusion containers. To investigate the influence of container materials, the stability of AP5346 after reconstitution and dilution in infusion containers was determined. The infusion containers investigated were composed of glass, polyvinyl chloride (PVC, intraflex) and low density polyethylene (LD-PE, Ecoflac). AP5346 was shown to be stable after reconstitution and dilution with 5% w/v dextrose in these infusion containers for at least 96 h at 2-8 degrees C in the dark and at room temperature with ambient light conditions. PMID:17069422

  15. Tank 241AP106, grab samples, 6AP96-1 through 6AP96-3 analytical results for the final report

    Microsoft Academic Search

    Esch; Westinghouse Hanford

    1996-01-01

    This document is the final report for tank 241-AP-106 grab samples. This document presents the analytical results for three samples (6AP-96-1, 6AP-96-2 and 6AP-96-3) taken from riser 1 @ 150° of tank 241-AP-1 06 on September 12, 1996. Analyses were performed in accordance with the Compatibility Grab Sampling and Analysis Plan (TSAP) (Sasaki, 1996) and the Data Quality Objectives for

  16. 55. QUARRY TILE CUTTERS, SECOND FLOOR, NORTH WING. WORKERS PRESSED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    55. QUARRY TILE CUTTERS, SECOND FLOOR, NORTH WING. WORKERS PRESSED THE CUTTERS INTO SLABS OF CLAY, LIFTED THEM ONTO DRYING BOARDS AND PRESSED THE PLUNGERS TO RELEASE THE CUT TILES. REPRODUCTIONS CUTTERS ARE NOT USED IN PRODUCTION. WOODEN FORMS FOR PRODUCING CLAY SLABS WITH ROLLING PINS REST AGAINST THE WALL. - Moravian Pottery & Tile Works, Southwest side of State Route 313 (Swamp Road), Northwest of East Court Street, Doylestown, Bucks County, PA

  17. The A&P Professor

    NSDL National Science Digital Library

    Patton, Kevin T.

    2012-04-06

    Kevin Patton is the president emeritus of the Human Anatomy and Physiology Society (HAPS) and he is also the brains behind the A&P (Anatomy & Physiology) Professor website. Patton has worked to create this online collection of resources for people teaching human anatomy and physiology, and it's a great counterpart to his blog of the same name. Visitors should start by looking over one of the five tabs at the top of the page, which include Resources, Topics, and How To. The How To contains resources for educators about producing online lectures and various in-class student response systems. The files here are dynamic, and they include interactive sections that make the material quite lively. Moving on, the Resources area includes an online version of an anatomy & physiology textbook created by Patton, along with links to other high-quality resources. Finally, the Lion's Den section of the site contains links to Patton's syllabi, course handouts, and a range of introductory materials for anyone who might be teaching a basic anatomy & physiology course.

  18. Tank 241-AP-107, grab samples, 7AP-99-1, 7AP-99-3 and 7AP-99-4 analytical results for the final report

    SciTech Connect

    BELL, K.E.

    1999-08-12

    This document is the format IV, final report for the tank 241-AP-107 (AP-107) grab samples taken in May 1999 to address waste compatibility concerns. Chemical, radiochemical, and physical analyses on the tank AP-107 samples were performed as directed in Compatibility Grab Sampling and Analysis Plan for Fiscal year 1999. Any deviations from the instructions provided in the tank sampling and analysis plan (TSAP) were discussed in this narrative. Interim data were provided earlier to River Protection Project (RPP) personnel, however, the data presented here represent the official results. No notification limits were exceeded.

  19. Brain Research Bullern. Vol. 21. pp. 473-477. t Pergamon Press plc. 1988. Printed in the U.S.A. 0361-923088 S3.00 -00 Tyrosine: Effects on Catecholamine Release

    E-print Network

    Wurtman, Richard

    _ leeelswith minorelevations inlevels ofDOPAC and HVA. its major metales. which ere not dose-related. The examined the possibility that the amino acid might actually enhance dopamine release in untreated animals

  20. Laboratory Director A.P. ALIVISATOS

    E-print Network

    Laboratory Director A.P. ALIVISATOS Research and Institutional Integrity Office M. E. MONTGOMERY Department Head Institutional Assurance H. K. HATAYAMA Director Lawrence Berkeley National Laboratory Universityof California Associate Laboratory Director Chief Operating Officer................ G. D. KUBIAK

  1. AP1000 design and construction integration

    SciTech Connect

    Winters, James W.; Clelland, Jill A. [Westinghouse Electric Company, P.O. Box 355, Pittsburgh, PA 15230-0355 (United States)

    2004-07-01

    Construction costs of commercial nuclear generating plants must be reduced in order to expand the future use of nuclear energy. Two of the drivers of plant construction costs are the cost of financing during the construction duration and the substantial amount of skilled craft labor hours needed on site during construction. The application of information technology (IT) has been used to understand and reduce both of these drivers by establishing parallel construction paths using modules and integrating construction sequence review into the design process. In a program sponsored by EPRI, Westinghouse has modeled the construction of AP1000 in '4D' to show its viability, to improve its logic, to improve the plant design for constructibility and overall to reduce time and risk in the construction schedule. The design of most of AP1000 was constrained to be a duplicate of AP600 except where components required expansion for the higher power level. As a result, the construction schedule for AP1000 is as mature and as robust as that for AP600. Two areas important to the construction of AP1000 did require some design work because they could not remain the same as AP1000. First, the turbine building had to be redesigned to accommodate the larger turbine and its support systems. Again, as much of the AP600 design and philosophy as possible was retained. The building required enlargement and the basemat, foundations, steel structure and structural modules required modification. As concrete, steel, and equipment were defined by the designers, they were matched to the original AP600 turbine building schedule. This forced designers to assemble files to be consistent with building assembly activities and to think about constructibility as they defined the final design. Second, the reinforcement structure within the concrete under and supporting the containment vessel required detail design. Westinghouse was fortunate to have the constructor Obayashi of Japan recommend a detailed design of this structure. It then was married to the overall construction plan in '4D' to ensure that the detail design did or did not impact the overall construction duration. With the extensive AP1000 3D design model graphics linked to a construction schedule during the design process, better reviews could be performed. Using '4D' techniques will be integrated more and more into the AP1000 design process as time goes on. (authors)

  2. American Society for Microbiology (ASM) Press

    NSDL National Science Digital Library

    American Society for Microbiology.

    ASM Press, the book publishing division of the American Society for Microbiology, publishes "reference manuals, scholarly monographs, and textbooks in all of the microbiological sciences." Recent releases include Pathology of Emerging Infections; Essential Procedures for Clinical Microbiology; Molecular Biotechnology: Principles & Applications of Recombinant DNA, 2nd Edition; Modification and Editing of RNA; and Escherichia coli O157:H7 and Other Shiga Toxin-Producing E. coli Strain, among others. Descriptions and ordering information are provided at the site.

  3. Computer Technology Institute & Press "DIOPHANTUS"

    E-print Network

    Bouras, Christos

    . . . . . . . . . Computer Technology Institute & Press "DIOPHANTUS" Research Unit 6 http://ru6.cti.gr Networks, Telematics and New Services 2014 #12;Computer Technology Institute & Press "Diophantus" - Research Unit 6 Computer Technology Institute & Press "DIOPHANTUS" The Computer Technology Institute

  4. I am the antenna: accurate outdoor AP location using smartphones

    Microsoft Academic Search

    Zengbin Zhang; Xia Zhou; Weile Zhang; Yuanyang Zhang; Gang Wang; Ben Y. Zhao; Haitao Zheng

    2011-01-01

    Today's WiFi access points (APs) are ubiquitous, and provide critical connectivity for a wide range of mobile networking devices. Many management tasks, e.g. optimizing AP placement and detecting rogue APs, require a user to efficiently determine the location of wireless APs. Unlike prior localization techniques that require either specialized equipment or extensive outdoor measurements, we propose a way to locate

  5. Impacts of Information Subsidies and Community Structure on Local Press Coverage of Environmental Contamination.

    ERIC Educational Resources Information Center

    Griffin, Robert J.; Dunwoody, Sharon

    1995-01-01

    Finds that a press kit sent by an environmental group to midwestern newspapers influenced them to delegate local staff to cover the story. Indicates that the press's function to report or raise issues concerning industrial toxic releases and related health risks is tempered by community structure and particularly by community reliance on

  6. [Changes in transmitter release at frog neuromuscular junction induced by 4-aminopyridine].

    PubMed

    Molgo, J; Lemeignan, M; Lechat, P

    1975-11-24

    4-aminopyridine (4-AP) at micromolar concentrations, increases the end-plate potential amplitude in curarized preparations and the mean quantal content in every preparation tested, but the spontaneous release is not modified by 4-AP. These results can explain the anticurare activity observed in the wole animal or in vitro. 4-AP prolongs the falling phase of the muscle action potential without change in the muscle membrane potential. PMID:3292

  7. PUBLISHED BY Microsoft Press

    E-print Network

    Hunt, Galen

    #12;PUBLISHED BY Microsoft Press A Division of Microsoft Corporation One Microsoft Way Redmond, Washington 98052-6399 Copyright 2011 by Microsoft Corporation All rights reserved. No part of the contents. Microsoft Press books are available through booksellers and distributors worldwide. For further information

  8. PUBLISHED BY Microsoft Press

    E-print Network

    Narasayya, Vivek

    #12;PUBLISHED BY Microsoft Press A Division of Microsoft Corporation One Microsoft Way Redmond, Washington 98052-6399 Copyright 2010 by Microsoft Corporation All rights reserved. No part of the contents the British Library. Microsoft Press books are available through booksellers and distributors worldwide

  9. PUBLISHED BY Microsoft Press

    E-print Network

    Twente, Universiteit

    #12;PUBLISHED BY Microsoft Press A Division of Microsoft Corporation One Microsoft Way Redmond, Washington 98052-6399 Copyright 2010 by Microsoft Corporation All rights reserved. No part of the contents from the British Library. Microsoft Press books are available through booksellers and distributors

  10. UNIVERSITY of WASHINGTON PRESS

    E-print Network

    Manchak, John

    UNIVERSITY of WASHINGTON PRESS Fall 2014 #12;CONTENTS NEW BOOKS1 CONTACT INFO49 SALES of Washington Press e-books from UPCC/Project Muse, ebrary, and EBSCO/ NetLibrary. Individuals may purchase our of the "Songs of Lake Anavatapta"30 Umatilla Dictionary11 Vacationland7 Welcome to Resisterville44 Wilderburbs6

  11. Plyler Prize and APS Fellow Introductions

    NASA Astrophysics Data System (ADS)

    Nathanson, Gilbert

    2014-03-01

    The Division of Chemical Physics is delighted to announce the 2013 APS Fellows sponsored by DCP and to honor the 2014 Earl K. Plyler Prize Award winner. The new APS Fellows are: Ilan Benjamin, Hua Guo, Manos Mavrikakis, Josef Paldus, Joern Siepmann, Hans-Peter Steinrueck, Douglas Tobias, Angela Wilson, and Yijing Yan. The citations for each awardee will be read out loud. I will also introduce Prof. Lai-Sheng Wang of the Department of Chemistry at Brown University, who was awarded the 2014 Plyler Prize for Molecular Spectroscopy and Dynamics. Please come learn about these extraordinary scientists during this prize session. Prof. Wang's Plyler Prize talk will follow immediately after this introduction. For more information, see http://www.aps.org/units/dcp/.

  12. Press laws in North Korea

    Microsoft Academic Search

    Kyu Ho Youm

    1991-01-01

    The press in the Democratic People's Republic of Korea (North Korea) is closely tied to its communist sociopolitical structures. The North Korean press finds its modus operandi in the Soviet Communist theory for its relationship with its government. This study examines the press laws and regulations in North Korea, pursuing three questions: (1) What is the status of the press

  13. Whoopers Released

    USGS Multimedia Gallery

    A Whooping crane chick is released into a temporary pen to acclimate before being released into the wild. Four of the endangered chicks, hatched and raised by their parents at the U.S. Geological Surveys Patuxent Wildlife Research Center in Laurel, Maryland, were released on Necedah Nat...

  14. Power Saving Control for Battery-Powered Portable WLAN APs

    NASA Astrophysics Data System (ADS)

    Ogawa, Masakatsu; Hiraguri, Takefumi

    This paper proposes a power saving control function for battery-powered portable wireless LAN (WLAN) access points (APs) to extend the battery life. The IEEE802.11 standard does not support power saving control for APs. To enable a sleep state for an AP, the AP forces the stations (STAs) to refrain from transmitting frames using the network allocation vector (NAV) while the AP is sleeping. Thus the sleep state for the AP can be employed without causing frame loss at the STAs. Numerical analysis and computer simulation reveal that the newly proposed control technique conserves power compared to the conventional control.

  15. RNAi screen identifies a role for adaptor protein AP-3 in sorting to the regulated secretory pathway

    PubMed Central

    Asensio, Cdric S.; Sirkis, Daniel W.

    2010-01-01

    The regulated release of proteins depends on their inclusion within large dense-core vesicles (LDCVs) capable of regulated exocytosis. LDCVs form at the trans-Golgi network (TGN), but the mechanism for protein sorting to this regulated secretory pathway (RSP) and the cytosolic machinery involved in this process have remained poorly understood. Using an RNA interference screen in Drosophila melanogaster S2 cells, we now identify a small number of genes, including several subunits of the heterotetrameric adaptor protein AP-3, which are required for sorting to the RSP. In mammalian neuroendocrine cells, loss of AP-3 dysregulates exocytosis due to a primary defect in LDCV formation. Previous work implicated AP-3 in the endocytic pathway, but we find that AP-3 promotes sorting to the RSP within the biosynthetic pathway at the level of the TGN. Although vesicles with a dense core still form in the absence of AP-3, they contain substantially less synaptotagmin 1, indicating that AP-3 concentrates the proteins required for regulated exocytosis. PMID:21149569

  16. APS 1002 Financial Engineering Instructor: Roy Kwon

    E-print Network

    APS 1002 Financial Engineering Instructor: Roy Kwon E-mail: rkwon@mie.utoronto.ca Course description: This course provides an introduction to financial engineering concepts especially relevant-income securities e.g. bonds, basic derivative securities e.g. options, portfolio (mean-variance) optimization

  17. APS Presents Awards at 2007 ABRCMS Conference

    NSDL National Science Digital Library

    APS Education Office (American Physiological Society Education Office)

    2008-02-01

    The APS presented awards to six minority undergraduate researchers for their oral and poster presentations in the physiological sciences at the Annual Biomedical Research Conference for Minority Students (ABRCMS) at the Austin Convention Center in Austin, TX from November 7-10, 2007. ABRCMS is a national conference designed to facilitate increased minority involvement in biomedical and behavioral science careers.

  18. Gapminder: An AP Human Geography Lab Assignment

    ERIC Educational Resources Information Center

    Keller, Kenneth H.

    2012-01-01

    This lesson is designed as a lab assignment for Advanced Placement (AP) Human Geography students wherein they use the popular Gapminder web site to compare levels of development in countries from different world regions. For this lesson, it is important for the teacher to practice with Gapminder before giving the assignment to students. (Contains

  19. The AP Descriptive Chemistry Question: Student Errors

    ERIC Educational Resources Information Center

    Crippen, Kent; Brooks, David W.

    2005-01-01

    For over a decade, the authors have been involved in a design theory experiment providing software for high school students preparing for the descriptive question on the Advanced Placement (AP) chemistry examination. Since 1997, the software has been available as a Web site offering repeatable practice. This study describes a 4-year project during

  20. APS Presents Awards at 2006 ABRCMS Conference

    NSDL National Science Digital Library

    APS Education Office (American Physiological Society Education Office)

    2007-04-01

    An article from The Physiologist. The APS presented awards to minority undergraduate researchers and was a major conference sponsor at the Annual Biomedical Research Conference for Minority Students (ABRCMS) at the Anaheim Convention Center and Anaheim Marriott hotel in Anaheim, CA from November 8-11, 2006.

  1. Period Refinement for AP Canum Venaticorum

    NASA Astrophysics Data System (ADS)

    Rudner, David Z.; McDuffie, Margaret

    1988-10-01

    The RR Lyrae variable AP CVN was examined for period changes in the interval 1964-1987 on plates taken at the Maria Mitchell Observatory. There is no evidence for period change in the interval. Revised linear elements are: JD(max)= 2443812.358 + 0.5746399 N.

  2. The Promise of AP World History

    ERIC Educational Resources Information Center

    Saldaa, Cristbal T.

    2013-01-01

    AP World History is the ideal history course. It introduces students to 10,000 years of world history, and demands critical reading, critical writing, and critical thinking skills on the part of both the teacher and the students. It requires students to build their expertise in reading their textbook, and places demands on the teacher to assign

  3. Lysosomal Targeting of Cystinosin Requires AP-3.

    PubMed

    Andrzejewska, Zuzanna; Nvo, Nathalie; Thomas, Lucie; Bailleux, Anne; Chauvet, Vronique; Benmerah, Alexandre; Antignac, Corinne

    2015-07-01

    Cystinosin is a lysosomal cystine transporter defective in cystinosis, an autosomal recessive lysosomal storage disorder. It is composed of seven transmembrane (TM) domains and contains two lysosomal targeting motifs: a tyrosine-based signal (GYDQL) in its C-terminal tail and a non-classical motif in its fifth inter-TM loop. Using the yeast two-hybrid system, we showed that the GYDQL motif specifically interacted with the ? subunit of the adaptor protein complex 3 (AP-3). Moreover, cell surface biotinylation and total internal reflection fluorescence microscopy revealed that cystinosin was partially mislocalized to the plasma membrane (PM) in AP-3-depleted cells. We generated a chimeric CD63 protein to specifically analyze the function of the GYDQL motif. This chimeric protein was targeted to lysosomes in a manner similar to cystinosin and was partially mislocalized to the PM in AP-3 knockdown cells where it also accumulated in the trans-Golgi network and early endosomes. Together with the fact that the surface levels of cystinosin and of the CD63-GYDQL chimeric protein were not increased when clathrin-mediated endocytosis was impaired, our data show that the tyrosine-based motif of cystinosin is a 'strong' AP-3 interacting motif responsible for lysosomal targeting of cystinosin by a direct intracellular pathway. PMID:25753619

  4. C-A/AP/#321 August 2008

    E-print Network

    C-A/AP/#321 August 2008 Higher order model power calculation of the 56 MHz SRF cavity E.M. Choi calculation of the 56 MHz SRF cavity E. M. Choi August 28, 2008 Abstract In this report, the HOM power superconducting RF cavity (SRF) is going to be installed in Relativistic Heavy Ion Collider (RHIC) ring

  5. Tank 241-AP-107 tank characterization plan

    SciTech Connect

    Schreiber, R.D.

    1994-12-06

    This document is a plan which serves as the contractual agreement between the Characterization Program, Sampling Operations, WHC 222-S Laboratory, and PNL 325 Analytical Chemistry Laboratory. The scope of this plan is to provide guidance for the sampling and analysis of samples from tank 241-AP-107.

  6. Two Successful Approaches to Teaching AP Government

    ERIC Educational Resources Information Center

    Ladd, Brian; Stepp, Heidi

    2013-01-01

    Amador Valley High School, in Pleasanton, California, uses two unique approaches to teaching Advanced Placement Government and Politics. AP Government consists of six units: Constitutional Underpinnings; Political Behavior and Political Beliefs; Mass Media, Interest Groups, and Political Parties; Institutions of Government; Civil Liberties and

  7. Analysis of temporal noise in CMOS APS

    Microsoft Academic Search

    Hui Tian; Boyd A. Fowler; Abbas El Gamal

    1999-01-01

    Temporal noise sets a fundamental limit on image sensor performance, especially under low illumination and in video applications. In a CCD image sensor, temporal noise is well studied and characterized. It is primarily due to the photodetector shot noise and the thermal and 1\\/f noise of the output charge to voltage amplifier. In a CMOS APS several addition sources contribute

  8. CMOS APS ASIC testing and evaluation

    Microsoft Academic Search

    S. Moussa; T. A. Elkhatib; H. Haddara; H. F. Ragaie

    2004-01-01

    An ASIC CMOS image Active Pixel Sensor (APS) with combined linear and logarithmic modes of operation is presented. The chip consists of a 64 x 64 pixel array, together with its digital control and timing circuits. Test structures including individual photodiodes and pixels are also integrated for characterization purpose. The chip features selectable linear and logarithmic modes of operation, digitally

  9. Structuring the AP Art History Course

    ERIC Educational Resources Information Center

    Herscher, Walter R.

    2013-01-01

    While AP (Advanced Placement) Art History may be taught within the art department in many schools, social studies teachers are equally capable of teaching the course well. They have the historical background to discuss the reasons for changes in art styles. A teacher's preparation is similar to teaching a course stressing political history,

  10. Functional description of APS beamline front ends

    SciTech Connect

    Kuzay, T.

    1993-02-01

    Traditional synchrotron sources were designed to produce bending magnet radiation and have proven to be an essential scientific tool. Currently, a new generation of synchrotron sources is being built that will be able to accommodate a large number of insertion device (ID) and high quality bending magnet (BM) sources. One example is the 7-GeV Advanced Photon Source (APS) now under construction at Argonne National Laboratory. The research and development effort at the APS is designed to fully develop the potential of this new generation of synchrotron sources. Of the 40 straight sections in the APS storage ring, 34 will be available for IDs. The remaining six sections are reserved for the storage ring hardware and diagnostics. Although the ring incorporates 80 BMs, only 40 of them can be used to extract radiation. The accelerator hardware shadows five of these 40 bending magnets, so the maximum number of BM sources on the lattice is 35. Generally, a photon beamline consists of four functional sections. The first section is the ID or the BM, which provides the radiation source. The second section, which is immediately outside the storage ring but inside a concrete shielding tunnel, is the front end, which is designed to control, define, and/or confine the x-ray beam. In the case of the APS, the front ends are designed to confine the photon beam. The third section, just outside the concrete shielding tunnel and on the experimental floor, is the first optics enclosure, which contains optics to filter and monochromatize the photon beam. The fourth section of a beamline consists of beam transports, additional optics, and experiment stations to do the scientific investigations. This document describes only the front ends of the APS beamlines.

  11. 76 FR 82079 - AP1000 Design Certification Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ...Quality Systems Manual, as described in the AP1000 Design Control Document...Design Report for the AP1000...Quality Systems Manual...proposed changes to the design of the PCCS to add manual maintenance...

  12. AP-42 ADDITIONS AND REVISIONS - RESIDENTIAL WOOD COMBUSTION

    EPA Science Inventory

    This project develops emission factors, etc., for residential fireplaces and woodstoves which are incorporated into AP-42. AP42 is a massive collection of material which describes processes which generate air emissions and presents emission factors and control effectiveness infor...

  13. APS/NIDDK Minority Travel Fellows Attend the 2012 APS Conferences

    NSDL National Science Digital Library

    APS Education Office (American Physiological Society Education Office)

    2012-12-01

    This article is on page 238 of The Physiologist, December 2012. The APS regularly awards Travel Fellowships for underrepresented minority students to attend the APS scientific meetings with funds provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). In the final year of support, these Fellowships provided up to $1,800 in expense reimbursement for meeting registration, transportation, meals, and lodging.

  14. Balancing Load of APs by Concurrent Association of Every Wireless Node with Many APs

    Microsoft Academic Search

    Dilip Sarkar; Uttam K. Sarkar

    2009-01-01

    Abstract In this paper we propose a novel method,for asso- ciating Wireless Mobile Nodes (WMNs) to Access Points (APs) in busy Wireless access networks. The proposed method,associates each WMN with many APs for mitigating load balancing problem in hot-spots. The proposed method,assumes that cmpTCP-type transport protocols are used in the end-points. The connections are established and maintained with the help

  15. The Cryptosporidium parvum ApiAP2 gene family: insights into the evolution of apicomplexan AP2 regulatory systems

    PubMed Central

    Oberstaller, Jenna; Pumpalova, Yoanna; Schieler, Ariel; Llins, Manuel; Kissinger, Jessica C.

    2014-01-01

    We provide the first comprehensive analysis of any transcription factor family in Cryptosporidium, a basal-branching apicomplexan that is the second leading cause of infant diarrhea globally. AP2 domain-containing proteins have evolved to be the major regulatory family in the phylum to the exclusion of canonical regulators. We show that apicomplexan and perkinsid AP2 domains cluster distinctly from other chromalveolate AP2s. Protein-binding specificity assays of C. parvum AP2 domains combined with motif conservation upstream of co-regulated gene clusters allowed the construction of putative AP2 regulons across the in vitro life cycle. Orthologous Apicomplexan AP2 (ApiAP2) expression has been rearranged relative to the malaria parasite P. falciparum, suggesting ApiAP2 network rewiring during evolution. C. hominis orthologs of putative C. parvum ApiAP2 proteins and target genes show greater than average variation. C. parvum AP2 domains display reduced binding diversity relative to P. falciparum, with multiple domains binding the 5?-TGCAT-3?, 5?-CACACA-3? and G-box motifs (5?-G[T/C]GGGG-3?). Many overrepresented motifs in C. parvum upstream regions are not AP2 binding motifs. We propose that C. parvum is less reliant on ApiAP2 regulators in part because it utilizes E2F/DP1 transcription factors. C. parvum may provide clues to the ancestral state of apicomplexan transcriptional regulation, pre-AP2 domination. PMID:24957599

  16. Relationship between ?-AP peptide aggregation and microglial activation

    Microsoft Academic Search

    Carme Casal; Joan Serratosa; Josep M. Tusell

    2002-01-01

    We compared the relationship between the state of aggregation of two peptides (?-AP 25-35 and ?-AP 1-42) and microglial activation. After 7 days at 37C ?-AP 25-35 was in an amorphous state and did not activate microglial cells. In the same conditions, aggregated ?-AP 1-42 activated these cells and caused changes in microglial ramification, increasing the proliferation index and inducing

  17. Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs.

    PubMed

    Sitges, M; Sanchez-Tafolla, B M; Chiu, L M; Aldana, B I; Guarneros, A

    2011-10-01

    4-Aminopyridine (4-AP) is a convulsing agent that in vivo preferentially releases Glu, the most important excitatory amino acid neurotransmitter in the brain. Here the ionic dependence of 4-AP-induced Glu release and the effects of several of the most common antiepileptic drugs (AEDs) and of the new potential AED, vinpocetine on 4-AP-induced Glu release were characterized in hippocampus isolated nerve endings pre-loaded with labelled Glu ([3H]Glu). 4-AP-induced [3H]Glu release was composed by a tetrodotoxin (TTX) sensitive and external Ca2+ dependent fraction and a TTX insensitive fraction that was sensitive to the excitatory amino acid transporter inhibitor, TBOA. The AEDs: carbamazepine, phenytoin, lamotrigine and oxcarbazepine at the highest dose tested only reduced [3H]Glu release to 4-AP between 50-60%, and topiramate was ineffective. Vinpocetine at a much lower concentration than the above AEDs, abolished [3H]Glu release to 4-AP. We conclude that the decrease in [3H]Glu release linked to the direct blockade of presynaptic Na+ channels, may importantly contribute to the anticonvulsant actions of all the drugs tested here (except topiramate); and that the significantly greater vinpocetine effect in magnitude and potency on [3H]Glu release when excitability is exacerbated like during seizures, may involve the increase additionally exerted by vinpocetine in some K+ channels permeability. PMID:21737246

  18. Study of CMOS APS Responsivity Enhancement: Ring-Shaped Photodiode

    E-print Network

    Study of CMOS APS Responsivity Enhancement: Ring-Shaped Photodiode Tatiana Danov, Igor Shcherback the possibilities of CMOS APS spectral response improvement are discussed. Thorough submicron scanning results sensitivity. Index Terms - APS (Active Pixel Sensor), CMOS image sensor, minority carriers, diffusion

  19. Beryllium window for an APS diagnostics beamline

    SciTech Connect

    Sheng, I.C.; Yang, B.X.; Sharma, Y.S.

    1997-09-01

    A beryllium (Be) window for an Advanced Photon Source (APS) diagnostics beamline has been designed and built. The window, which has a double concave axisymmetrical profile with a thickness of 0.5 mm at the center, receives 160 W/mm{sup 2} (7 GeV/100 mA stored beam) from an undulator beam. The window design as well as thermal and thermomechanical analyses, including thermal buckling of the Be window, are presented.

  20. Leading modes of variability in AP simulations

    NASA Astrophysics Data System (ADS)

    Toniazzo, Thomas

    2015-04-01

    We present a study of the low-frequency variability of the zonal-mean circulation in full-physics, steady-state AP simulations. The leading mode appears to conform to a delayed-oscillator paradigm. We analyze the involvement of fluxes of moisture and angular momentum, both in the inner domain and at the boundaries, in shaping and sustaining this mode, and we discuss its sensitivity to peculiarities of simulations with current GCMs, such as non-conservation.

  1. Vacuum chamber thermal protection for the APS

    Microsoft Academic Search

    S. L. Kramer; E. A. Crosbie; S. Kim; R. Wehrle; M. Yoon

    1989-01-01

    The authors summarize the results of a task group that studied the vacuum-chamber thermal protection problem for the Advanced Photon Source (APS). It is pointed out that the high-power-density photon beams in the proposed next generation of synchrotron light sources introduce new risks to the integrity of the ring vacuum chambers. In these machines, power densities are such that vacuum

  2. Estrogen receptor pathways to AP1

    Microsoft Academic Search

    Peter J. Kushner; David A. Agard; Geoffrey L. Greene; Thomas S. Scanlan; Andrew K. Shiau; Rosalie M. Uht; Paul Webb

    2000-01-01

    Estrogen receptor (ER) binds to estrogen response elements in target genes and recruits a coactivator complex of CBP-pl60 that mediates stimulation of transcription. ER also activates transcription at AP-1 sites that bind the Jun\\/Fos transcription factors, but not ER. We review the evidence regarding mechanisms whereby ER increases the activity of Jun\\/Fos and propose two pathways of ER action depending

  3. Modeling and simulation of CMOS APS

    Microsoft Academic Search

    Beatriz Blanco-Filgueira; P. Lopez; Diego Cabello; J. Ernst; H. Neubauer; J. Hauer

    2009-01-01

    This work studies the importance of the peripheral collection in the overall photoresponse in deep sub-micron CMOS 3T active pixel sensors (APS), focusing on the contribution of the bottom surface of the depletion region. We analyze a semi-analytical expression, inspired by previous works, that models the photoresponse of a set of fabricated pixels with octagonal photodiodes that could be easily

  4. In-pixel autoexposure cmos aps

    Microsoft Academic Search

    Orly Yadid-Pecht; Alexander Belenky

    2003-01-01

    A CMOS active pixel sensor (APS) with in-pixel auto- exposure and a wide dynamic-range linear output is described. The chip features a unique architecture enabling a customized number of additional bits per pixel per readout, with minimal effect on the sensor spatial or temporal resolution. By utilizing multiple read- outs via real-time feedback, each pixel in the field of view

  5. Cultural Diversity in AP Art History

    ERIC Educational Resources Information Center

    Bolte, Frances R.

    2006-01-01

    Teaching AP Art History is like running on a treadmill that is moving faster than a teacher can run. Many teachers are out of breath before the end of the term and wonder how in the world they can cover every chapter. Because time is short and art from pre-history through to the present, including the non-European traditions, must be covered, this

  6. 32 CFR 635.11 - Release of information under the Freedom of Information Act (FOIA).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...Information 635.11 Release of information under the Freedom...Act (FOIA). (a) The release and denial authorities...requests from members of the press will be coordinated with the...public affairs officer prior to release of records under the...

  7. Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases

    PubMed Central

    Leslie, Nick R; McLennan, Alexander G; Safrany, Stephen T

    2002-01-01

    Background The human genome contains at least 18 genes for Nudix hydrolase enzymes. Many have similar functions to one another. In order to understand their roles in cell physiology, these proteins must be characterised. Results We have characterised two novel human gene products, hAps1, encoded by the NUDT11 gene, and hAps2, encoded by the NUDT10 gene. These cytoplasmic proteins are members of the DIPP subfamily of Nudix hydrolases, and differ from each other by a single amino acid. Both metabolise diadenosine-polyphosphates and, weakly, diphosphoinositol polyphosphates. An apparent polymorphism of hAps1 has also been identified, which leads to the point mutation S39N. This has also been characterised. The favoured nucleotides were diadenosine 5',5"'-pentaphosphate (kcat/Km = 11, 8 and 16 103M-1s-1 respectively for hAps1, hAps1-39N and hAps2) and diadenosine 5',5"'-hexaphosphate (kcat/Km = 13, 14 and 11 103M-1s-1 respectively for hAps1, hAps1-39N and hAps2). Both hAps1 and hAps2 had pH optima of 8.5 and an absolute requirement for divalent cations, with manganese (II) being favoured. Magnesium was not able to activate the enzymes. Therefore, these enzymes could be acutely regulated by manganese fluxes within the cell. Conclusions Recent gene duplication has generated the two Nudix genes, NUDT11 and NUDT10. We have characterised their gene products as the closely related Nudix hydrolases, hAps1 and hAps2. These two gene products complement the activity of previously described members of the DIPP family, and reinforce the concept that Ap5A and Ap6A act as intracellular messengers. PMID:12121577

  8. Notice to fruit growers and nurserymen relative to the naming and release of GulfSnow peach

    Technology Transfer Automated Retrieval System (TEKTRAN)

    GulfSnow peach is jointly released for grower trial by the U.S. Department of Agriculture, Agricultural Research Service (Byron, GA), Georgia Agricultural Experiment Station and Florida Agricultural Experiment Station. GulfSnow was previously tested as AP06-09W and originated from a cross of AP98-3...

  9. Switchable aptamers for biosensing and bioseparation of viruses (SwAps-V).

    PubMed

    Wehbe, Mohamed; Labib, Mahmoud; Muharemagic, Darija; Zamay, Anna S; Berezovski, Maxim V

    2015-05-15

    There is a widespread interest in the development of aptamer-based affinity chromatographic methods for purification of biomolecules. Regardless of the many advantages exhibited by aptamers when compared to other recognition elements, the lack of an efficient regeneration technique that can be generalized to all targets has encumbered further integration of aptamers into affinity-based purification methods. Here we offer switchable aptamers (SwAps) that have been developed to solve this problem and move aptamer-based chromatography forward. SwAps are controlled-affinity aptamers, which have been employed here to purify vesicular stomatitis virus (VSV) as a model case, however this technique can be extended to all biologically significant molecules. VSV is one oncolytic virus out of an arsenal of potential candidates shown to provide selective destruction of cancer cells both in vitro and in vivo. These SwAps were developed in the presence of Ca(2+) and Mg(2+) ions where they cannot bind to their target VSV in absence of these cations. Upon addition of EDTA and EGTA, the divalent cations were sequestered from the stabilized aptameric structure causing a conformational change and subsequently release of the virus. Both flow cytometry and electrochemical impedance spectroscopy were employed to estimate the binding affinities between the selected SwAps and VSV and to determine the coefficient of switching (CoS) upon elution. Among fifteen sequenced SwAps, four have exhibited high affinity to VSV and ability to switch upon elution and thus were further integrated into streptavidin-coated magnetic beads for purification of VSV. PMID:25190090

  10. Columbia Engineering AP Credit Chart 2011-2011 2 June 2011 *Up to 3 AP credits may be applied toward minor requirements.

    E-print Network

    Hone, James

    Columbia Engineering AP Credit Chart 2011-2011 2 June 2011 *Up to 3 AP credits may be applied Engineering AP Credit Chart 2011-2011 2 June 2011 *Up to 3 AP credits may be applied toward minor requirements credit must start with Calculus II. #12;Columbia Engineering AP Credit Chart 2011-2011 2 June 2011 *Up

  11. Cytotoxic Evaluation of 3-Aminopyridine-2-Carboxaldehyde Thiosemicarbazone, 3-AP, in Peripheral Blood Lymphocytes of Patients with Refractory Solid Tumors using Electron Paramagnetic Resonance.

    PubMed

    Kolesar, Jill M; Sachidanandam, Kamakshi; Schelman, William R; Eickhoff, Jens; Holen, Kyle D; Traynor, Anne M; Alberti, Dona B; Thomas, James P; Chitambar, Christopher R; Wilding, George; Antholine, William E

    2011-01-01

    PURPOSE: 3-AP (3-aminopyridine-2-carboxaldehyde thiosemicarbazone, 3-AP) is a metal chelator that potently inhibits the enzyme ribonucleotide reductase, RR, which plays a key role in cell division and tumor progression. A sub-unit of RR has a non-heme iron and a tyrosine free radical, which are required for the enzymatic reduction of ribonucleotides to deoxyribonucleotides. The objective of the study was to determine whether 3-AP affects its targeted action by measuring EPR signals formed either directly or indirectly from low molecular weight ferric-3-AP chelates. METHODS: Peripheral blood lymphocytes were collected from patients with refractory solid tumors at baseline and at 2, 4.5 and 22 hours after 3-AP administration. EPR spectra were used to identify signals from high-spin Fe-transferrin, high-spin heme and low-spin iron or copper ions. RESULTS: An increase in Fe-transferrin signal was observed, suggesting blockage of Fe uptake. It is hypothesized that formation of reactive oxygen species by FeT(2) or CuT damage transferrin or the transferrin receptor. An increase in heme signal was also observed, which is a probable source of cytochrome c release from the mitochondria and potential apoptosis. In addition, increased levels of Fe and Cu were identified. CONCLUSION: These results, which were consistent with our earlier study validating 3-AP-mediated signals by EPR, provide valuable insights into the in vivo mechanism of action of 3-AP. PMID:21373381

  12. Drill Press Work Sample.

    ERIC Educational Resources Information Center

    Shawsheen Valley Regional Vocational-Technical High School, Billerica, MA.

    This manual contains a work sample intended to assess a handicapped student's interest in and to screen interested students into a training program in basic machine shop I. (The course is based on the entry level of the drill press operator.) Section 1 describes the assessment, correlates the work performed and worker traits required for

  13. ARTICLE IN PRESS UNCORRECTEDPROOF

    E-print Network

    Guerra, Vasco

    ARTICLE IN PRESS UNCORRECTEDPROOF Please cite this article as: V. Guerra, R. de Abreu, Comment on Communicated by P.R. Holland Abstract In a recent article [M. Consoli, E. Costanzo, Phys. Lett. A 333 (2004 a growing number of articles questioning the standard interpretation of special rela- tivity is appearing

  14. Electromagnetic field analysis of septum magnet for APS positron accumulator ring

    SciTech Connect

    Yokoi, Toshiaki; Turner, L.R.

    1995-07-01

    This report consists of three parts. The first part describes a numerical analysis method for the electromagnetic field analysis of a septum magnet. A novel improvement to the treatment of exciting currents in the time-domain is proposed. The second part discusses numerical predictions of the electromagnetic characteristics of the APS PAR septum. The time variations of stray field and eddy currents are shown for three magnet designs. The last part explores how decreasing the septum material conductivity affects the stray field. The decrease of conductivity may be caused by an inadequate manufacturing of the septum material. The significance of a high quality septum, or flat interface between copper and iron, is emphasized from a point of view of stray field. An ideal method for joining two different metals without distortion, called HIP (Hot Isostatic Pressing), is introduced and recommended based on the authors` experience.

  15. Ozone mitigation tests at the APS

    SciTech Connect

    Kuzay, T.M.; Collins, J.T.; Pisharody, M.; Job, P.K.; Wang Zhibi

    1996-09-01

    Ozone is generated in the APS experimental stations whenever the x-ray beam has a chance to interact with air. Ozone concentrations in an experimental station have to be below a certain defined limit (current OSHA regulations specify 0.08 ppm as the maximum limit) before an experimenter can reenter the hutch. This limit is said to be currently under study for a downward adjustment. One method of depleting the ozone generated in an experimental station is mitigation through either adsorption or direct destruction. In recent tests, both methods were tried using commercially available units. Test results and some analytical predictions are presented.

  16. APS Living History Project Continues to Grow

    NSDL National Science Digital Library

    2008-02-01

    This is an article from The Physiologist. The APS Living History Project continues to gain traction as members invite senior members at their institutions to reminisce about their careers. Our members? efforts are consistent with Council?s goal when it initiated the program ? to chronicle the exploits and experiences of senior members of the Society. Over the last several years, we have lost a number of eminent physiologists who made significant contributions to the discipline of physiology and to the Society. The Living History Project is one way to capture the images, experiences and wisdom of our senior members for the benefit of future generations of physiologists.

  17. APS/123-QED FIG. 1: LSI

    E-print Network

    Hasegawa, Shuji

    APS/123-QED -- -- I. 10-9 m 10-6 m 1 -- Fig.1 2 0.1 m FIG. 1: LSI 2 scanning tunneling microscopy, STM 1980 #12;2 FIG. 2: SiH4 II. Fig.2 Si (3s)2 (3p)2 sp3 Si Si Fig.3 Fig.4 GaAs GaAlAs (2DEG) molecular beam epitaxy, (chemical va- por deposition) Fig.5 3 GaAs III. Fig.2 #12;3 FIG. 3: ( ) Fig.2 Si

  18. Applying Pesticides in Potato Health Management, ed. D. Johnson. APS Press

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Pesticides are an important component of most management programs for nematodes, diseases, weeds, and insects that impact yield and/or quality in potatoes. The appropriate pesticide, correct timing of application, effective rate, and appropriate method of application must be selected for effective p...

  19. MR imaging during arterial-portography (MR-AP) in the detection of hepatic tumor: comparison with CT-AP.

    PubMed

    Kajiya, Y; Nakajo, M; Miyazono, N; Kajiya, Y; Fujiyoshi, F; Ichinari, N

    1997-01-01

    This study was undertaken to compare the detection rate of hepatic space occupying lesion (SOL)s between computed tomography during arterial portography (CT-AP) and magnetic resonance imaging during arterial portography (MR-AP) and the differences in time intensity curve on MR-AP between HCC, metastatic tumor, FNH, and hemangioma. We performed CT-AP and MR-AP in 17 patients including 14 cases of HCC and one each of metastasis, FNH, and hemangioma. MR-AP was performed by Turbo-FLASH sequence. There was no statistically significant difference between CT-AP and MR-AP in detecting satellite lesions in terms of smallest diameter and number of flow defects (p > 0.05). Hemangioma showed rapid enhancement after the first pass and, consequently, the same enhancement as the hepatic parenchyma. MR-AP was comparable to CT-AP in the detection of hepatic SOLs. Hemangioma showed an enhancement pattern different from those of HCC, metastatic tumor, and FNH, which showed patterns similar to each other. PMID:9495785

  20. Radiation characteristics of scintillator coupled CMOS APS for radiography conditions

    Microsoft Academic Search

    Kwang Hyun Kim; Soongpyung Kim; Dong-Won Kang; Dong-Kie Kim

    2006-01-01

    Under industrial radiography conditions, we analyzed short-term radiation characteristics of scintillator coupled CMOS APS (hereinafter SC CMOS APS). By means of experimentation, the contribution of the transmitted X-ray through the scintillator to the properties of the CMOS APS and the afterimage, generated in the acquired image even at low dose condition, were investigated. To see the transmitted X-ray effects on

  1. The APS control system network upgrade.

    SciTech Connect

    Sidorowicz, K. v.; Leibfritz, D.; McDowell, W. P.

    1999-10-22

    When it was installed,the Advanced Photon Source (APS) control system network was at the state-of-the-art. Different aspects of the system have been reported at previous meetings [1,2]. As loads on the controls network have increased due to newer and faster workstations and front-end computers, we have found performance of the system declining and have implemented an upgraded network. There have been dramatic advances in networking hardware in the last several years. The upgraded APS controls network replaces the original FDDI backbone and shared Ethernet hubs with redundant gigabit uplinks and fully switched 10/100 Ethernet switches with backplane fabrics in excess of 20 Gbits/s (Gbps). The central collapsed backbone FDDI concentrator has been replaced with a Gigabit Ethernet switch with greater than 30 Gbps backplane fabric. Full redundancy of the system has been maintained. This paper will discuss this upgrade and include performance data and performance comparisons with the original network.

  2. ANL/APS/TB-34 Experimental Facilities Division

    E-print Network

    Kemner, Ken

    ......................................................................25 2.7 Interlock Systems and Instrumentation.....................................................................25 2.7.1 The APS Personnel Safety System ............................................................26 2.7.2 The Equipment Protection System

  3. Project W-211, initial tank retrieval systems, description of operations for 241-AP-102 and 241-AP-104

    SciTech Connect

    RIECK, C.A.

    1999-02-25

    The primary purpose of the Initial Tank Retrieval Systems (ITRS) is to provide systems for retrieval of radioactive wastes stored in underground double-shell tanks (DSTS) for transfer to alternate storage, evaporation, pretreatment or treatment, while concurrently reducing risks associated with safety watch list and other DSTs. This Description of Operations (DOO) defines the control philosophy for the waste retrieval system for tanks 241-AP-102 (AP-102) and 241-AP-104 (AP-104). This DOO will provide a basis for the detailed design of the Retrieval Control System (RCS) for AP-102 and AP-104 and establishes test criteria for the RCS. The test criteria will be used during qualification testing and acceptance testing to verify operability.

  4. The AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells.

    PubMed

    Grtsch, Bettina; Brachs, Sebastian; Lang, Christiane; Luther, Julia; Derer, Anja; Schltzer-Schrehardt, Ursula; Bozec, Aline; Fillatreau, Simon; Berberich, Ingolf; Hobeika, Elias; Reth, Michael; Wagner, Erwin F; Schett, Georg; Mielenz, Dirk; David, Jean-Pierre

    2014-10-20

    The cornerstone of humoral immunity is the differentiation of B cells into antibody-secreting plasma cells. This process is tightly controlled by a regulatory gene network centered on the transcriptional repressor B lymphocyte-induced maturation protein 1 (Blimp1). Proliferation of activated B cells is required to foster Blimp1 expression but needs to be terminated to avoid overshooting immune reactions. Activator protein 1 (AP-1) transcription factors become quickly up-regulated upon B cell activation. We demonstrate that Fra1, a Fos member of AP-1, enhances activation-induced cell death upon induction in activated B cells. Moreover, mice with B cell-specific deletion of Fra1 show enhanced plasma cell differentiation and exacerbated antibody responses. In contrast, transgenic overexpression of Fra1 blocks plasma cell differentiation and immunoglobulin production, which cannot be rescued by Bcl2. On the molecular level, Fra1 represses Blimp1 expression and interferes with binding of the activating AP-1 member c-Fos to the Blimp1 promoter. Conversely, overexpression of c-Fos in Fra1 transgenic B cells releases Blimp1 repression. As Fra1 lacks transcriptional transactivation domains, we propose that Fra1 inhibits Blimp1 expression and negatively controls plasma cell differentiation through binding to the Blimp1 promoter. In summary, we demonstrate that Fra1 negatively controls plasma cell differentiation by repressing Blimp1 expression. PMID:25288397

  5. In vitro dissolution and in vivo gamma scintigraphic evaluation of press-coated salbutamol sulfate tablets.

    PubMed

    Li, Wei; Shi, Cai-Hong; Sheng, Yi-Ling; Cui, Ping; Zhao, Yu-Qing; Zhang, Xiang-Rong

    2013-12-01

    The aim of this study was to investigate the in vitro and in vivo performance of salbutamol sulfate press-coated tablets for delayed release. The in vitro release behavior of press-coated tablets with the outer layer of PEG 6000/ Eudragit S100 blends (2:1) in pH 1.2 (0.1 mol L-1 HCl) and then pH 6.8 buffer solution was examined. Morphological change of the press-coated tablet during in vitro release was recorded with a digital camera. Release of salbutamol sulfate from press-coated tablets was less than 5 % before 3 h and was completed after 8 h in pH 6.8 phosphate buffer solution. In vivo gamma scintigraphy study carried out on healthy men indicated that the designed system released the drug in lower parts of the GI tract after a lag time of 5 hours. The results showed the capability of the system of achieving delayed release of the drug in both in vitro and in vivo gamma scintigraphy studies. PMID:24451078

  6. Student Press Law Center

    NSDL National Science Digital Library

    Created in 1974, the Student Press Law Center (SPLC) is the ??nation's only legal assistance agency devoted exclusively to educating high school and college journalists about the rights and responsibilities embodied in the First Amendment.? Based in Arlington, Virginia the Center provides free legal advice and information along with low-cost educational materials. On its homepage, visitors can make their way through sections that include Know Your Rights and Classroom Resources. In Know Your Rights, visitors can learn about the rights of high school journalists and educators, peruse an online law library, and check out an interactive map tracking the latest legal developments in student press rights nationally. Moving on, the Classroom Resources area brings together dozens of classroom handouts, presentations, and some fun short quizzes regarding libel, privacy, and other media-law issues.

  7. Inner City Press

    NSDL National Science Digital Library

    Based in the South Bronx, the Inner City Press has been publishing a newspaper focused on low-income neighborhoods nationwide since 1987. A few months ago, the organization went online with a weekly publication featuring original and engaging investigative and analytical pieces from a selection of beats, including the Federal Reserve, Community Reinvestment, Insurance Redlining, Wall Street, Environmental Justice, and Banks, among others. The most recent issue (August 30) includes concise reports on predatory lending, the economic crisis in Ecuador, press leaks and the Federal Reserve, and a round-up of bank news. The site also provides overviews and related resources for Community Reinvestment, the Inner City Public Interest Law Center, Environmental Justice, Insurance Redlining, and related topics.

  8. New Prairie Press

    NSDL National Science Digital Library

    The New Prairie Press (NPP) was founded at the Kansas State University Libraries in 2007. Created as an open access publishing venture, they focus their work on journals in the humanities, social sciences, and arts. Currently, they publish several journals that include The Baltic International Yearbook of Cognition, Logic and Communication and the Online Journal of Rural Research & Policy. They also provide editorial support to journals such as The Lion and the Unicorn, which is published by Johns Hopkins University Press. Visitors to the site can read issues from all five of their main journals, and they can also register to receive updates and create lists of their favorite articles. Additionally, users can search all of the journals at one time with the "Journal Content" search engine.

  9. Genome-Wide Identification of the Target Genes of AP2-O, a Plasmodium AP2-Family Transcription Factor

    PubMed Central

    Kaneko, Izumi; Iwanaga, Shiroh; Kato, Tomomi; Kobayashi, Issei; Yuda, Masao

    2015-01-01

    Stage-specific transcription is a fundamental biological process in the life cycle of the Plasmodium parasite. Proteins containing the AP2 DNA-binding domain are responsible for stage-specific transcriptional regulation and belong to the only known family of transcription factors in Plasmodium parasites. Comprehensive identification of their target genes will advance our understanding of the molecular basis of stage-specific transcriptional regulation and stage-specific parasite development. AP2-O is an AP2 family transcription factor that is expressed in the mosquito midgut-invading stage, called the ookinete, and is essential for normal morphogenesis of this stage. In this study, we identified the genome-wide target genes of AP2-O by chromatin immunoprecipitation-sequencing and elucidate how this AP2 family transcription factor contributes to the formation of this motile stage. The analysis revealed that AP2-O binds specifically to the upstream genomic regions of more than 500 genes, suggesting that approximately 10% of the parasite genome is directly regulated by AP2-O. These genes are involved in distinct biological processes such as morphogenesis, locomotion, midgut penetration, protection against mosquito immunity and preparation for subsequent oocyst development. This direct and global regulation by AP2-O provides a model for gene regulation in Plasmodium parasites and may explain how these parasites manage to control their complex life cycle using a small number of sequence-specific AP2 transcription factors. PMID:26018192

  10. Metallized solid rocket propellants based on AN/AP and PSAN/AP for access to space

    NASA Astrophysics Data System (ADS)

    Levi, S.; Signoriello, D.; Gabardi, A.; Molinari, M.; Galfetti, L.; Deluca, L. T.; Cianfanelli, S.; Klyakin, G. F.

    2009-09-01

    Solid rocket propellants based on dual mixes of inorganic crystalline oxidizers (ammonium nitrate (AN) and ammonium perchlorate (AP)) with binder and a mixture of micrometric-nanometric aluminum were investigated. Ammonium nitrate is a low-cost oxidizer, producing environment friendly combustion products but with lower specific impulse compared to AP. The better performance obtained with AP and the low quantity of toxic emissions obtained by using AN have suggested an interesting compromise based on a dual mixture of the two oxidizers. To improve the thermal response of raw AN, different types of phase stabilized AN (PSAN) and AN/AP co-crystals were investigated.

  11. Filter Press Building

    E-print Network

    Bush, W. M.

    "FILTER PRESS BUILDING" AVON LAKE WATER POLLUTION CONTROL CENTER HEAT PUMP HEATING AND COOLING SYSTEM William M. Bush, P.E. The Cleveland Electric Illuminating Company Cleveland, Ohio ABSTRACT The high heat value of the plant's treated wa..." exemplifies the ultimate all-electric application. INTRODUCTION The City of Avon Lake launched a program in 1983 to eKpand and modernize its water pollution control facilities. A part of this expansion was construction of a separate building to house a...

  12. A comparison of impulse drying to double felted pressing on pilot- scale shoe presses and roll presses

    SciTech Connect

    Orloff, D.I.

    1992-08-01

    Pilot-scale shoe press and roll press experiments have been conducted to compare impulse drying and double felted pressing. Both ceramic coated and Beloit Type C press rolls have been evaluated. The experiments show that impulse drying can provide significantly higher outgoing solids than double felled pressing at the same impulse. For example, at an impulse of 0.234 MPa seconds (34 psi seconds), sheets at an ingoing solids of 52% were impulse dried (using the Beloit Type C press roll) to 68% solids while optimized double felled pressing could only yield press dryness of, at most, 60%.

  13. : The AE9/AP9 Next Generation Radiation Specification Models - Progress Report

    NASA Astrophysics Data System (ADS)

    OBrien, Paul; Johnston, W. Robert; Huston, Stuart; Ginet, Gregory

    2015-04-01

    The AE9/AP9 model has now been released to the global satellite design community. Since the release of version 1.0, we have been focused on documenting the model so that it is suitable for consideration as an international standard. We are also working on incorporating new data sources, such as THEMIS, TACSAT-4, and NASA's Van Allen Probes. Finally, we are scoping out architectural improvements to enable improvements requested by industry: improved stitching between the plasma and radiation models, local time dependence in the plasma model, longitude dependence in the electron radiation model, and solar cycle variation in the low altitude protons. We provide a brief update on the status of the model, plans for the future, and progress on international agreements.

  14. The Relationship between Advanced Placement and College Graduation. 2005 AP Study Series, Report 1

    ERIC Educational Resources Information Center

    Dougherty, Chrys; Mellor, Lynn; Jian, Shuling

    2006-01-01

    This study explores the relationship between college graduation rates and student participation and success in Advanced Placement (AP) courses and exams. We reviewed three approaches to examining this relationship: 1) comparing the college graduation rates of AP and non-AP students; 2) comparing the college graduation rate of AP and non-AP

  15. Measure Your Sew - How: Pressing Points.

    E-print Network

    Odle-Kemp, Marlene

    1979-01-01

    good looking garment that needs little final pressing. Pressing differs from ironing. When pressing, the iron is lifted up and down rather than back and forth, applying some pressure with each move. Pressing prevents stretching or pulling the fabric... off grain and helps retain the original fabric texture. Ironing, on the other hand, is used to remove wrinkles and to restore crispness and shine to fabrics. Pressing can speed the construction process. Use pressing as a substitute for hand...

  16. Raising Rigor, Getting Results: Lessons Learned from AP Expansion

    ERIC Educational Resources Information Center

    Wakelyn, David

    2009-01-01

    Advanced Placement (AP), which enables high school students to take introductory college-level courses, is the nation's oldest example of a rigorous, common curriculum. Students who score well on AP exams are more likely to persist in college and earn a degree. The Advanced Placement Expansion project of the National Governors Association Center

  17. AP-102/104 Retrieval control system qualification test procedure

    SciTech Connect

    RIECK, C.A.

    1999-05-18

    This Qualification Test Procedure documents the results of the qualification testing that was performed on the Project W-211, ''Initial Tank Retrieval Systems,'' retrieval control system (RCS) for tanks 241-AP-102 and 241-AP-104. The results confirm that the RCS has been programmed correctly and that the two related hardware enclosures have been assembled in accordance with the design documents.

  18. Exact noise analysis of a CMOS BDJ APS

    Microsoft Academic Search

    Sylvain Feruglio; Victor Fouad Hanna; Georges Alqui; Gabriel Vasilescu

    2005-01-01

    At low illumination levels, the performance of image sensors is severely limited by their intrinsic electrical noise. In the buried double junction (BDJ) active pixel sensor (APS), as in any CMOS image sensor, noise is primarily due to the photodetector and to the in-pixel transistors. In this paper, we present an exact noise analysis of CMOS BDJ APS in charge

  19. CMOS APS crosstalk: modeling, technology and design trends

    Microsoft Academic Search

    Shcherback Igor; Belenky Alex; O. Yadid-Pecht

    2004-01-01

    In this work based on a unique sub-micron scanning system (S-cube system) measurements of the lateral photoresponse and crosstalk (CTK) in CMOS active pixel sensor (APS) have been investigated and an analytical model was developed for crosstalk estimation in photodiode based CMOS APS arrays. Based on handy process and design data only, our model estimates the CTK contribution to the

  20. Low-noise readout using active reset for CMOS APS

    Microsoft Academic Search

    Boyd A. Fowler; Michael D. Godfrey; Janusz Balicki; John Canfield

    2000-01-01

    Pixel reset noise sets the fundamental detection limit on photodiode based CMOS image sensors. Reset noise in standard active pixel sensor (APS) is well understood and is of order kT\\/C. In this paper we present a new technique for resetting photodiodes, called active reset, which reduces reset noise without adding lag. Active reset can be applied to standard APS. Active

  1. AP-42 ADDITIONS AND REVISIONS - PAVED AND UNPAVED ROAD DUST

    EPA Science Inventory

    This project develops emission factors, etc., for paved and unpaved roads which are incorporated into AP-42. AP42 is a massive collection of material which describes processes which generate air emissions and presents emission factors and control effectiveness information. As re...

  2. AP-42 ADDITIONS AND REVISIONS - LANDFILLS (COMBUSTION CONTROLS)

    EPA Science Inventory

    This project develops emission factors, etc., for landfills, in particular for combustion devices fed by landfill gas, for incorporation into AP-42. AP-42 is a massive collection of information concerning processes which generate air emissions and presents emission factors and co...

  3. AP233: An Information Model for Systems Engineering

    NASA Technical Reports Server (NTRS)

    Siebes, Georg

    2009-01-01

    In today's world, information is abundant. We have no problems generating it. But we are challenged to find, organize, and exchange information. center dot A standardized model of information can help. Such a model nearly completed its development for Systems Engineering. It is referred to as AP233 (AP = Application Protocol).

  4. PressRelease|TheFitzwilliamMuseum 16 March 2011

    E-print Network

    Zeki, Semir

    the Bronze Age to Tudor times, a new exhibition opening this month at The Fitzwilliam Museum showcases the Civil War discovered in the Old Hall of Pembroke College, Cambridge A Bronze-Age axe hoard, an Iron from as early as the Iron Age, whose owners never returned through personal misfortune or even sheer

  5. PressRelease|TheFitzwilliamMuseum 12 February 2009

    E-print Network

    Zeki, Semir

    's impact on nineteenth century art Endless Forms Charles Darwin, Natural Science and the Visual Arts by the Wellcome Trust and the Philecology Foundation, Endless Forms: Charles Darwin, Natural Science of Natural Selection (1859) The notion of a link between Darwin, the scientist, and the visual arts might

  6. PressRelease|TheFitzwilliamMuseum 23 November 2009

    E-print Network

    Zeki, Semir

    Museum Contemporary prints, miniature Japanese sculpture and major works by Maggi Hambling feature legend. Maggi Hambling (b. 1945) Rising Wave, 2009 Maggi Hambling: The Wave 27 April 18 July 2010 A major exhibition of new and challenging sea paintings by celebrated contemporary artist Maggi Hambling

  7. PressRelease|TheFitzwilliamMuseum 04 March 2010

    E-print Network

    Zeki, Semir

    by one of Britain's most distinguished contemporary artists Maggi Hambling: The Wave 27 April 8 August of Britain's most distinguished contemporary artists - Maggi Hambling (b. 1945). Maggi Hambling Rising Wave, 2009 Maggi Hambling Maggi Hambling: The Wave (27 April 8 August 2010) brings together a powerful

  8. PressRelease|TheFitzwilliamMuseum Trumpington Street

    E-print Network

    Zeki, Semir

    to enrich the collection through gift and bequest. Collectors such as the textile manufacturer Frank Hindley to be able to represent the wider aspects of these artists' work: Pissarro as a painter of snow, Monet as sculptors as well as painters, and Rodin's sculpture can be seen in potent juxtaposition with Monet

  9. For Immediate Release Office of the Press Secretary

    E-print Network

    Rathbun, Julie A.

    as President by the Constitution and the laws of the United States of America, and to obtain recommendations's Commission on Implementation of United States Space Exploration Policy By the authority vested in me concerning implementation of the new vision for space exploration activities of the United States

  10. PressRelease|TheFitzwilliamMuseum Updated: 17 June 2011

    E-print Network

    Zeki, Semir

    the Collection 8 March 17 July 2011 (closing date extended) An exhibition this spring at the Fitzwilliam Museum paintings" Italian Drawings: Highlights from the Collection marks the publication of a comprehensive new of Paintings, Drawings and Prints. The exhibition is accompanied by a selection of workshops for adults

  11. PRESS RELEASE Ipsen announce a sponsored research agreement

    E-print Network

    Knipe, David M.

    at the New England Primate Research Center and Department of Microbiology and Immunobiology of Harvard strategy, current views and assumptions. Such statements involve known and unknown risks and uncertainties

  12. Quality of Pharmaceutical Industry Press Releases Based on Original Research

    Microsoft Academic Search

    Bindee Kuriya; Elana C. Schneid; Chaim M. Bell; Lise Lotte Gluud

    2008-01-01

    Not Available Bibtex entry for this abstract Preferred format for this abstract (see Preferences) Find Similar Abstracts: Use: Authors Title Return: Query Results Return items starting with number Query Form Database: Astronomy Physics arXiv e-prints

  13. PressRelease|TheFitzwilliamMuseum 14 October 2009

    E-print Network

    Zeki, Semir

    , presenting fine 20th -century specimens from the art nouveau to contemporary art medals, honouring Pollard of fifteenth-century Italian craftsmanship to contemporary art medals, A Lifetime of Connoisseurship: Graham's role as a founder of the British Art Medal Society. Showcasing an intriguingly diverse range of medals

  14. Press Release `The highest ranked independent art college in the

    E-print Network

    Stell, John

    provide a great foundation for successful careers in the creative industries." Leeds College of Art for over 160 years. We are proud of the vibrant and dynamic culture that has developed and matured since undergraduate programmes. Our focus is to put student's talents to practical use, so their creativity

  15. For Immediate Release Office of the Press Secretary

    E-print Network

    Catell, who is the event host. He's the Chairman of the United States Energy Association. I want to thank to be here for the 16th annual Energy Efficiency Forum. It's an important forum. By advancing the national reduce our energy consumption, and to help us achieve a vital national goal, and that is making America

  16. OFFICE OF COMMUNICATIONS PRESS RELEASE JANUARY 6, 2011

    E-print Network

    Wechsler, Risa H.

    National Accelerator Laboratory and Stanford University. "It's an emblematic object," he said; the Crab a pulse of radiation every 33 milliseconds, like clockwork. Though it's only 10 miles across CALIFORNIA 94025 USA SLAC is operated by Stanford University for the U.S. Department of Energy #12;SLAC

  17. Press Release Does your child have a creative streak?

    E-print Network

    Stell, John

    years 11 to 13 we also offer Portfolio Preparation, helping students to engage in specialist art & design activities, build confidence, develop life skills, and prepare a broad portfolio to show their creativity is channelled towards a successful career or postgraduate study. Our students and staff create

  18. PressRelease|TheFitzwilliamMuseum Trumpington Street

    E-print Network

    Zeki, Semir

    to interiors and nudes, and including little- seen sketches and studies, Sargent, Sickert & Spencer examines in North Wales (1938) Interiors and the nude: reviewing images such as Sickert's Mornington Crescent Nude depictions of nude female models Spencer, God and love: an examination of Spencer's overarching themes

  19. PressRelease|TheFitzwilliamMuseum 24 July 2008

    E-print Network

    Zeki, Semir

    of the interaction between the ancient Greeks and the cultures of the Black Sea. This exhibition offers a unique of Ancient Georgia 2 October 2008 4 January 2009 Fitzwilliam Museum hosts only UK showing of a spectacular archaeological excavations in the land sought out by the Argonauts of Greek mythology The first ever UK

  20. PressRelease|TheFitzwilliamMuseum Trumpington Street

    E-print Network

    Zeki, Semir

    sculpture once belonging to Emperor Hadrian The Lansdowne Relief Dark grey limestone AD 100 150 Height: 56 Bonham-Carter Fund and other individuals. An important Roman sculpture featuring classical sea myths and other individuals. One of the most imposing items in the Museum's Greek and Roman gallery, the Lansdowne

  1. Failure of plastic press release buttons in automobile seat belts

    Microsoft Academic Search

    Russell F. Dunn; Richard H. McSwain; Terry Mills; Brian Malone

    2005-01-01

    In the late 1980s and early 1990s Honda, Nissan, Mitsubishi, Mazda, Suzuki, Subaru, Isuzu and Daihatsu and other automobile manufacturers modified their restraint system seat belt buckle assemblies in several models of vehicles. These automobile manufacturers incorporated plastic seat belt buckle assemblies manufactured by Takata Corporation as the 52 and A7 model series [National Highway Transportation Safety Administration (NHTSA), 1997,

  2. PRESS RELEASE LSE leads consortium to advance and strengthen the

    E-print Network

    Stevenson, Paul

    with extensive experience in the area of health policy, health economics, health of Public Health, Spain; 8) Pan American Health Organisation (PAHO), USA; 9 of Health Technology Assessment (HTA) The London School of Economics and Political

  3. Press Release EU-funded research collaboration on

    E-print Network

    Ferrari, Patrik L.

    and exploring new ways of how to treat epilepsy. "Targets and biomarkers for antiepileptogenesis" (EPITARGET). A German project management SME, GABO:mi, will manage the administrative tasks of the project. Epilepsy existing antiepileptic drugs are not able to prevent or cure the disease. Moreover, no disease

  4. Press Releases and News Investment appeal of privatisations

    E-print Network

    Chaudhuri, Sanjay

    also examined company profitability, operating efficiency and capital expenditure in the three years in a company to the public. This is usually done through an initial public offering, also known as a privatised billion (S$554 billion) for companies from 2000 to 2008. Much of this increase occurred in China. Between

  5. For Immediate Release Office of the Press Secretary

    E-print Network

    Electricity Supply Expand the use of clean coal technology and enable a future for America s most abundant resource through the President's FutureGen Initiative and his 10-year Clean Coal Power Initiative which

  6. APS Position Statements- APS Guiding Principles for the Care and Use of Vertebrate Animals in Research and Training

    NSDL National Science Digital Library

    2010-07-16

    The Guiding Principles for the Care and Use of Vertebrate Animals in Research and Training are an updated version of a document first adopted by the APS Council in 1953. The Guiding Principles represent a code of ethics for APS members who work with animals. They provide a framework intended to promote the humane treatment of animals and are also used to evaluate research submitted for publication in APS journals. The update is intended to clarify certain elements of the Guiding Principles and make them easier to apply in practical situations. In addition, because the Guiding Principles are based upon U.S. animal welfare requirements, the update adds provisions to address the fact that other countries have different animal welfare requirements. This change was needed because of the increasing number of physiologists from around the world who are joining the APS and submitting articles for publication in APS journals.

  7. Hot Off the Press

    NSDL National Science Digital Library

    Barry Schlegel

    2006-10-01

    Environmental Health Perspectives (EHP) , a peer-reviewed environmental health research journal (published by the National Institute of Environmental Health Sciences, part of the National Institutes of Health,) provides the EHP Student Edition for high school and college teachers and their students. Each edition contains news articles that summarize a wide variety of scientific information and original research, which are paired with complementary lessons that introduce students to hot-off-the-press science. This article presents ways to integrate EHP's online content in the classroom.

  8. Word Press Editorial Calendar

    NSDL National Science Digital Library

    If you're a blogger, you probably make plans both grand and modest about publishing new posts and content. One can be easily overwhelmed by such plans, and it's nice to have a way to keep up to date with such important matters. For those using WordPress, the Editorial Calendar plugin allows users to view all of their posts, their status, and information about how many posts are planned for a given day or week. It's quite easy to use and it is compatible with all operating systems.

  9. Residual radiation studies at AP0

    SciTech Connect

    Alexander J Elwyn et al.

    2002-06-19

    The radiation environment at the NuMI experiment has received a lot of attention in the last few years in preparation for project construction. One important issue is the induced radioactivation of the components in the beam line and the shielding materials. This arises from irradiation by hadrons that are generated in the target. Since the level of the residual activity has to be considered when determining access procedures for maintenance during NuMI operation, an understanding of the properties of the remnant radiation is important. To this end, experimental studies were performed in the target vault at AP0 which is similar in design to the NuMI target area. Here 120 GeV protons bombard a target, generating the hadrons that produce the induced radioactivity. Two sets of samples each consisting of three small cylindrical or rectangular solids of iron and steel, one sample of aluminum, and one of concrete were irradiated. One set was hung just below the bottom of a module near the lithium lens (in-vault), and the other was placed on top of the modules downstream of this location (above-vault), just beneath the movable concrete roof of the vault at AP0. Further, four thin activation foils of Au, Au+Cd, In, and Al (along with small disks of the same iron, aluminum, and concrete samples discussed above) were mounted on four 10.2 cm diameter Al disks, one placed on the in-vault module and three at above-vault downstream locations as well. The radioactivity of all these materials on the 10.2 cm Al disks was determined at the Radioisotope Analysis Facility in an attempt to characterize the radionuclides produced during irradiation. The activities of the thin foils were employed in an effort to unfold a spectrum of the neutrons produced during the hadronic cascades in the target. The MARS Monte Carlo code (MO95, MO00) was used to predict and analyze the residual radiation produced during the beam irradiation. New subroutines have been developed for the MARS14 version providing reliable estimation of residual dose rates in arbitrary composite materials for arbitrary irradiation and cooling times (RA01). The results of the simulations have been compared with the measurements in Ref. (RA01) and this comparison will be summarized here.

  10. Status of Potential New Commercial Nuclear Reactors in the United Release Date: December 2007

    E-print Network

    Noble, James S.

    1 Status of Potential New Commercial Nuclear Reactors in the United States Release Date: December for building new nuclear power reactors in the United States. Evidence of this includes press releases and conditionally operate new commercial nuclear reactors. Actual applications will also be included on future

  11. Iran Weekly Press Digest

    NSDL National Science Digital Library

    The Iran Weekly Press Digest, a weekly review of the Iranian press in English, contains a number of articles on the summit of the Organisation of the Islamic Conference and its significance for Iran in its archived and current issues. The eighth summit of the Organisation of the Islamic Conference was recently held in Tehran, Iran. Iran recently hosted representatives from 55 countries to a three-day Muslim summit in Tehran in a move which is being seen as a new phase in the country's re-emergence after years of relative isolation. The acceptance of Iran's invitations by senior figures from former enemies such as Saudi Arabia and Iraq has been portrayed by Iranian leaders and many others as a strong setback for US attempts to politically quarantine that country. Representatives considered 142 resolutions prepared by foreign ministers on issues including Middle East peace, regional conflicts, terrorism and human rights. However, perhaps the most significant outcome of the summit has been a reintroduction of Iran into the Muslim community of nations. Capitalizing on current anti-American sentiments and the recent election of a relatively moderate president, Iran hopes to rebuild its relationships with its neighbors and once again become a regional leader, a position it held for approximately 3000 years.

  12. [Formation of transcription factors AP-1 during learning in Helix].

    PubMed

    Grinkevich, L N; Lisachev, P D; Merkulova, T I

    2001-06-01

    An increase in the DNA-binding activity for the AP-1-family factors was shown to occur after food aversion conditioning. Learning experiments in vitro enhanced the DNA-binding activity. Effects of simultaneous action of serotonine and calcium on activation of transcriptional AP-1 factors was suppressed by inhibitor of calcium/calmodulin-dependent protein-kinases KN62 as well as by inhibitor of MAP-kinases PD98059. The co-operative induction of transcriptional AP-1 family factors activation by serotonine-induced and calcium-dependent regulatory systems may be one of the mechanisms of aversive conditioning in the CNS of the land snail. PMID:11534202

  13. Electrohydraulic-impulse pressing of refractory powders

    Microsoft Academic Search

    K. N. Bogoyavlenskii; P. A. Kuznetsov; K. K. Mertens; V. V. Podgornyi; L. V. Kravets; V. M. Yam

    1982-01-01

    Conclusions It was experimentally established that it is possible to use electrohydraulic-impulse pressing to improve the basic physical properties of articles prepared from low-plasticity refractory powders. The advantages of making articles by combined pressing, including static pressing in a rigid mold and final electrohydraulic-impulse pressing were demonstrated.

  14. Determining pressing curves for industrial refractory bodies

    Microsoft Academic Search

    V. E. Vernikovskii; A. P. Lapin; S. A. Losev; S. A. Klass

    1969-01-01

    Conclusions This article describes real pressing curves for the commonest semidry refractory bodies. The curves may be used by refractories production technologists and press designers. The mathematical relationship is established for pressing parameters and specific fabrication pressure, and the empirical pressing coefficients are worked out.

  15. An AP4B1 frameshift mutation in siblings with intellectual disability and spastic tetraplegia further delineates the AP-4 deficiency syndrome.

    PubMed

    Abdollahpour, Hengameh; Alawi, Malik; Kortm, Fanny; Beckstette, Michael; Seemanova, Eva; Komrek, Vladimr; Rosenberger, Georg; Kutsche, Kerstin

    2015-02-01

    The recently proposed adaptor protein 4 (AP-4) deficiency syndrome comprises a group of congenital neurological disorders characterized by severe intellectual disability (ID), delayed or absent speech, hereditary spastic paraplegia, and growth retardation. AP-4 is a heterotetrameric protein complex with important functions in vesicle trafficking. Mutations in genes affecting different subunits of AP-4, including AP4B1, AP4E1, AP4S1, and AP4M1, have been reported in patients with the AP-4 deficiency phenotype. We describe two siblings from a non-consanguineous couple who presented with severe ID, absent speech, microcephaly, growth retardation, and progressive spastic tetraplegia. Whole-exome sequencing in the two patients identified the novel homozygous 2-bp deletion c.1160_1161delCA (p.(Thr387Argfs*30)) in AP4B1. Sanger sequencing confirmed the mutation in the siblings and revealed it in the heterozygous state in both parents. The AP4B1-associated phenotype has previously been assigned to spastic paraplegia-47. Identification of a novel AP4B1 alteration in two patients with clinical manifestations highly similar to other individuals with mutations affecting one of the four AP-4 subunits further supports the observation that loss of AP-4 assembly or functionality underlies the common clinical features in these patients and underscores the existence of the clinically recognizable AP-4 deficiency syndrome. PMID:24781758

  16. Simultaneous and sequential display of ICU AP-chest images

    NASA Astrophysics Data System (ADS)

    Gur, David; Good, Walter F.; King, Jill L.

    1992-05-01

    The display of a large number of projection radiographs (e.g., AP chest images) for comparison purposes poses potential problems for any electronic environment. In an attempt to assess the concept of rapid sequential viewing, 10 series of AP chest images were each reviewed on a high-resolution workstation under two conditions: (1) simultaneous display of each series in a mosaic configuration; and (2) separate image display in which each image was viewed individually in a rapid sequential mode. In our study, the sequential display was believed subjectively to be of comparable or higher quality by four of six readers. Diagnostic performance (patient improved; no change; patient condition worsened) was comparable for both display modes. Readers were somewhat more comfortable with the simultaneous (mosaic) configuration. Our preliminary results indicate that after minimal training, rapid sequential viewing of AP-chest images may be a reasonable alternative for the display of a series of AP chest images in the ICU.

  17. QCD on the Massively Parallel Computer AP1000

    NASA Astrophysics Data System (ADS)

    Akemi, K.; Fujisaki, M.; Okuda, M.; Tago, Y.; Hashimoto, T.; Hioki, S.; Miyamura, O.; Takaishi, T.; Nakamura, A.; de Forcrand, Ph.; Hege, C.; Stamatescu, I. O.

    We present the QCD-TARO program of calculations which uses the parallel computer AP1000 of Fujitsu. We discuss the results on scaling, correlation times and hadronic spectrum, some aspects of the implementation and the future prospects.

  18. DETAIL VIEW OF AP 50, MAIN FLOOR LEVEL, PLATFORM BSOUTH, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF AP 50, MAIN FLOOR LEVEL, PLATFORM B-SOUTH, HB-3, FACING NORTHWEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  19. DETAIL VIEW OF AP 66, MAIN FLOOR LEVEL, PLATFORM BNORTH, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF AP 66, MAIN FLOOR LEVEL, PLATFORM B-NORTH, HB-3, FACING NORTH - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  20. DETAIL VIEW OF AP 65, SECOND FLOOR LEVEL, PLATFORM DSOUTH, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF AP 65, SECOND FLOOR LEVEL, PLATFORM D-SOUTH, HB-3, FACING NORTHWEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  1. Our Organic World Pre-AP Chemistry-Project

    E-print Network

    Our Organic World Pre-AP Chemistry-Project Purpose: To study specific areas of organic chemistry developing the learning book just remember what you liked to do when you were a little kid." 5. Time limit

  2. Divisions Iv-V / Working Group ap & Related Stars

    NASA Astrophysics Data System (ADS)

    Mathys, Gautier; Cunha, Margarida; Dworetsky, Michael; Kochukhov, Oleg; Kupka, Friedrich; LeBlanc, Francis; Monier, Richard; Paunzen, Ernst; Pintado, Olga; Piskunov, Nikolai; Ziznovsky, Jozef

    2012-04-01

    The purpose of the Working Group on Ap and Related Stars (ApWG) is to promote and facilitate research about stars in the spectral type range from B to early F that exhibit surface chemical peculiarities and related phenomena. This is a very active field of research, in which a wide variety of new developments have taken place since 2009, as illustrated by the following selected highlights.

  3. An overview of the APS 352-MHz rf systems

    SciTech Connect

    Nassiri, A.; Cours, A.; Grelick, A.; Horan, D.; Kang, Y.W.; Kustom, R.L.; Smith, T.L.; Song, J. [Argonne National Lab., IL (United States). Advanced Photon Source

    1997-08-01

    The Advanced Photon Source (APS) is a 7-GeV full energy positron storage ring for generating synchrotron radiation with an injector. The booster synchrotron rf system consists o a single 1-MW klystron which drives four five-cell cavities at 352 MHz. The storage ring cavities consist of four groups of four single cells powered by two 1-MW klystrons for 100-mA operation. An overview of the operation of the APS 352-MHz rf systems is presented.

  4. Again, Maryland Ranks #1 in Advanced Placement (AP) Exam Performance

    ERIC Educational Resources Information Center

    Maryland State Department of Education, 2010

    2010-01-01

    For a second year in a row, Maryland ranked first nationwide in the percentage of public school students scoring 3 or higher on at least one AP (Advanced Placement) exam. A score of 3 or higher on the 5-point scale is considered mastery of college-level work. Maryland also continues to show strong gains in the number of students taking an AP exam,

  5. Ce-doped scintillators: LSO and LuAP

    Microsoft Academic Search

    A. Lempicki; J. Glodo

    1998-01-01

    In this paper we compare the scintillator performance of the two of the leading contenders for Positron Emission Tomography, both cerium doped: Lu2SiO5 (LSO) and LuAlO3 (LuAP). LSO crystals come in two categories, characterized by high (H) or low (L) light output. Such a distinction is not found in LuAP, but its output is consistently lower than that of LSO-H.

  6. Photodiode Peripheral Utilization Effect on CMOS APS Pixel Performance

    Microsoft Academic Search

    Suat Utku Ay

    2008-01-01

    A photodiode (PD)-type CMOS active pixel sensor (APS) pixel is comprised of a reverse-biased p-n-junction diode (PD) for photon conversion and charge storage, and a number of MOS transistors. Junction capacitance of the PD has two major components; bottom plate (area) and side wall (periphery). Both play important roles in the electro-optical performance of PD-APS pixels. This paper reports PD

  7. A New Photon Counting Detector: Intensified CMOS-APS

    Microsoft Academic Search

    Giovanni Bonanno; Massimiliano Belluso; Antonio Cal; Alessandro Carbone; Rosario Cosentino; Angelo Modica; Salvo Scuderi; Cristina Timpanaro; Michela Uslenghi

    2004-01-01

    A new type of position sensor (CMOS-APS) used as readout system in MCP-based intensified photon counter is presented. Thanks to CMOS technology, the pixel addressing and the readout circuits as well as the analogue-to-digital converters are integrated into the chip. These unique characteristics make the CMOS-APS a very compact, low power consumption, photon counting system. The more classical Photon Counting

  8. Scintillator and CMOS APS Imager for Radiography Conditions

    Microsoft Academic Search

    Kwang Hyun Kim; Young Soo Kim

    2008-01-01

    We evaluated X-ray image performance for several scintillators and a CMOS APS imager by both diagnostic radiography and mammography conditions. Commercially available scintillators such as Lanex screen, needle structured CsI (Tl), and fiber optic structured CsI (Tl) were coupled with a CMOS APS imager. The X-ray machines used in this study were fixed tube voltage of 80 kVp and variable

  9. Evaluation of CMOS APS imager for digital radiography and mammography

    Microsoft Academic Search

    Kwang Hyun Kim; Jeon Sung Chae; Sun Woo Yuk; Young Soo Kim; Young Ki Chi; Gyuseong Cho

    2003-01-01

    We evaluated image performance of scintillator coupled CMOS APS imager for radiography and mammography conditions, respectively. 80 kVp and 28 kVp of X-ray tube voltage at the SID of 720 mm and 600 mm were set for each condition. Commercially available scintillator such as Lanex screen, needle structured CsI(Tl), and fiber optic structured CsI (Tl) were coupled CMOS APS imager.

  10. Emergency Operating Procedures (EOPs) for the AP1000 Simulator

    Microsoft Academic Search

    Yuichi Hayashi; Gianfranco Saiu; Richard F. Wright

    2006-01-01

    The AP1000 is two-loop 1100 MWe advanced pressurized water reactor (PWR) that uses passive safety features to enhance plant safety and to provide significant and measurable improvements in plant simplification, reliability, investment protection and plant costs. The AP1000 uses proven technology, which builds on over 30 years of operating PWR experience. The API000 final design certification was approved by the

  11. Apollo 7 - Press Kit

    NASA Technical Reports Server (NTRS)

    1968-01-01

    Contents include the following: General release. Mission objectives. Mission description. Flight plan. Alternate missions. Experiments. Abort model. Spacecraft structure system. The Saturn 1B launch vehicle. Flight sequence. Launch preparations. Mission control center-Houston. Manned space flight network. Photographic equipment. Apollo 7 crew. Apollo 7 test program.

  12. Stony Brook Press

    NSDL National Science Digital Library

    The State University of New York at Stony Brook has an impressive set of digital collections spanning poetry, history, and geography. This particular section of the digital initiative, known as DSpace, brings together past issues of the Stony Brook Press. This institutional journal is published every two weeks, and this particular archive contains over 560 issues. It's far from dry as it reports on everything from new literary endeavors to changes within the faculty. As one of the largest schools in the state system, this school has undergone many changes in the past twenty years, and this publication is a great way to learn more about the school's history. Also it is easy to search through past issues via the advanced search option.

  13. American Press Institute

    NSDL National Science Digital Library

    2005-01-01

    The American Press Institute has been providing high-quality resources for practicing journalists for years, and now visitors with a penchant for the field can find out about some of these helpful materials on this site. While their homepage can be a bit visually hard to follow, the resources here are top-notch, and include some first-rate publications, such as ??Reaching Latino Audiences? and ??Women, Men and Newsroom Leadership?. The ??Journalist??s Toolbox? is a real find, as it contains a number of easy-to-use resources on such materials as copyediting, Iraq, and reporting on technology affairs. Additionally, there is a fine area dedicated to business journalism, including helpful hints on how best to deploy statistics in such pieces of writing. Overall, the site is extremely useful, and it is worth visiting several times.

  14. Neuron, Vol. 18, 10251038, June, 1997, Copyright 1997 by Cell Press Synergies and Coincidence Requirements

    E-print Network

    Tsien, Roger Y.

    Neuron, Vol. 18, 10251038, June, 1997, Copyright 1997 by Cell Press Synergies and Coincidence, and Berg- Parallel fiber synapses onto Purkinje neurons in acute man glia cells but not in cerebellar PCsGMP-dependent protein kinase cally released inside thePurkinje neuron, showing that (PKG), though a role for cyclic

  15. Solving Symbolic Equations with PRESS

    E-print Network

    Sterling, L.; Bundy, Alan; Byrd, L.; O'Keefe, R.; Silver, B.

    1982-01-01

    We outline a program, PRESS (PRolog Equation Solving System) for solving symbolic, transcendental, non-differential equations. The methods used for solving equations are described, together with the service facilities. The ...

  16. Fulfillment-based Fairness: A New Fairness Notion for Multi-AP Wireless Hotspots

    E-print Network

    Qiao, Daji

    Fulfillment-based Fairness: A New Fairness Notion for Multi-AP Wireless Hotspots Wei Zhou and Daji: {zhouwei, daji}@iastate.edu Abstract-- Today, most wireless hotspots deploy multiple APs (Access Points proposed for single-AP wireless hotspots exhibit various performance anomalies in multi-AP wireless

  17. Past, Present, and Future of AP Chemistry: A Brief History of Course and Exam Alignment Efforts

    ERIC Educational Resources Information Center

    Magrogan, Serena

    2014-01-01

    As part of the Advanced Placement (AP) Program's commitment to continually enhance alignment with current best practices in college-level learning, the AP Program is currently evaluating and redesigning courses and exams, one of which launched during the 2013-2014 academic school year: AP chemistry. The history of the AP chemistry course and

  18. Pyrometry in the Multianvil Press: New approach for temperature measurement in large volume press experiments

    NASA Astrophysics Data System (ADS)

    Sanehira, T.; Wang, Y.; Prakapenka, V.; Rivers, M. L.

    2008-12-01

    Temperature measurement in large volume press experiments has been based on thermocouple emf, which has well known problems: unknown pressure dependence of emf [e.g., 1], chemical reaction between thermocouple and other materials, deformation related texture development in the thermocouple wires [2], and so on. Thus, different techniques to measure temperatures in large volume press experiments other than thermocouples are required to measure accurate temperatures under high pressures. Here we report a new development using pyrometry in the multianvil press, where temperatures are derived on the basis of spectral radiometry. Several high pressure runs were conducted using the 1000 ton press with a DIA module installed at 13 ID-D GSECARS beamline at Advanced Photon Source (APS) [3]. The cubic pressure medium, 14 mm edge length, was made of soft-fired pyrophyllite with a graphite furnace. A moissanite (SiC) single crystal was built inside the pressure medium as a window for the thermal emission signal to go through. An MgO disk with 1.0 mm thickness was inserted in a gap between the top of the SiC crystal and thermocouple hot junction. The bottom of the window crystal was in direct contact with the tip of the anvil, which had a 1.5 mm diameter hole drilled all the way through the anvil axis. An optical fiber was inserted in this hole and the open end of fiber was in contact with the SiC crystal. Thermal spectral radiance from the inner cell assembly was obtained via the fiber and recorded by an Ocean Optics HP2000 spectrometer. The system response of spectrometer was calibrated by a tungsten ribbon ramp (OL550S, Optronic Laboratories, Inc.) with standard of spectral radiance. The cell assembly was compressed up to target value of 15 tons and then temperature was increased up to 1573 K. Radiation spectra were mainly obtained above 873 K and typical integration time was 1 ms or 10 ms. Data collection was done in the process of increase and decrease of temperature. In one in-situ X-ray experiment, pressures near the thermocouple were derived from the equations of state for gold [4] or MgO [5], and the pressure values varied up to approximately 1 GPa at various temperatures. Two different calculations were made to infer temperature based on pyrometry. One was made based on Planck radiation function and the other was made by the J-function, which was defined based on the law of Wien [6]. Calculated temperatures above about 1000 K were generally consistent with those obtained from the thermocouple emf. However, below about 1000 K, temperatures based on pyrometry in the process of increase of temperature were way off from those obtained by thermocouple emf. Recent results and future improvements will be discussed. Reference [1] I. C. Getting and G. C. Kennedy J. Appl. Phys., 41, 4552-4562, 1970. [2] J. Li, C. Hadidiacos, H.-K. Mao, Y. Fei and R. J. Hemley High Pressure Research, 23, 389-401, 2003. [3] Y. Wang, M. Rivers, S. Sutton, N. Nishiyama, T. Uchida, T. Sanehira Phys. Earth Planet. Inter. in press. [4] S.-H. Shim, T. S. Duffy and K. Takemura Earth Planet. Sci. Lett., 203, 729-739, 2002. [5] M. Matsui, S. C. Parker and M. Leslie Am. Mineral., 85, 312-316, 2000. [6] T. Yagi and J. Susaki, in High-Pressure Research: Application to Earth and Planetary Sciences, edited by Y. Syono and M. H. Manghnani, pp.51-54, TERRAPUB, Tokyo / AGU, Washington D.C., 1992.

  19. EPICS Input/Output Controller (IOC) application developer`s guide. APS Release 3.12

    SciTech Connect

    Kraimer, M.R.

    1994-11-01

    This document describes the core software that resides in an Input/Output Controller (IOC), one of the major components of EPICS. The basic components are: (OPI) Operator Interface; this is a UNIX based workstation which can run various EPICS tools; (IOC) Input/Output Controller; this is a VME/VXI based chassis containing a Motorola 68xxx processor, various I/O modules, and VME modules that provide access to other I/O buses such as GPIB, (LAN), Local Area Network; and this is the communication network which allows the IOCs and OPIs to communicate. Epics provides a software component, Channel Access, which provides network transparent communication between a Channel Access client and an arbitrary number of Channel Access servers.

  20. Syllabus Fall 2014 | APS 1010 Cognitive and Psychological Foundations of Effective Leadership | Prof. Robin Sacks 1 APS 1010 Cognitive and Psychological Foundations of Effective Leadership

    E-print Network

    Prodi, Aleksandar

    Syllabus Fall 2014 | APS 1010 Cognitive and Psychological Foundations of Effective Leadership | Prof. Robin Sacks 1 APS 1010 Cognitive and Psychological Foundations of Effective Leadership Prof. Robin Sacks Course Description This course investigates the cognitive and psychological foundations

  1. The unusual roAp star KIC 8677585

    NASA Astrophysics Data System (ADS)

    Balona, L. A.; Catanzaro, G.; Crause, L.; Cunha, M. S.; Gandolfi, D.; Hatzes, A.; Kabath, P.; Uytterhoeven, K.; De Cat, P.

    2013-07-01

    KIC 8677585 is a roAp star in the Kepler field which is unique in that there are four low-frequency variations of unknown origin in addition to more than 20 high-frequency roAp modes. We analysed all available spectroscopy and conclude that the star has a constant radial velocity and most likely not a binary. We estimate its effective temperature to be Teff = 7300 200 K from high-dispersion spectra. We present an analysis of 829 d of Kepler short-cadence data which shows clear frequency and amplitude variations with a time-scale of months. The dominant low-frequency peak at 3.142 d-1 has the same frequency and amplitude variation as one of the roAp modes. We therefore conclude that the low frequencies are oscillations in the roAp star itself, but the driving mechanism is unknown. We find several frequency spacings among the roAp modes equal to the dominant low frequency, suggestive of non-linear interactions. There is also a clear spacing of 37.2 ?Hz which we interpret as the large separation and deduce that log g = 3.90 0.03. Models with these parameters which take into account the effect of the magnetic field on the oscillations are able to reproduce the observed range of roAp frequencies, but not the observed large separation. It is found that the properties of the oscillations are sensitive to the assumed stellar parameters and that a more detailed analysis is required. The fact that low frequencies are closely coupled to the roAp frequencies calls into question our current understanding of pulsation in these stars.

  2. Heterologous expression of ApGSMT2 and ApDMT2 genes from Aphanothece halophytica enhanced drought tolerance in transgenic tobacco

    Microsoft Academic Search

    Ying HeChunmei; Chunmei He; Lihua Li; Zhili Liu; Aifang Yang; Juren Zhang

    2011-01-01

    The glycine-methylation biosynthetic pathway of glycinebetaine (GB) has been investigated, but only a few studies on GB accumulation\\u000a in transgenic higher plants have utilized this pathway. In this study, two methyltransferase genes named ApGSMT2 and ApDMT2, encoding proteins catalyzing GB biosynthesis from glycine, were cloned from a relative strain of Aphanothece halophytica. The potential roles of ApGSMT2 and ApDMT2 in

  3. Validation of the new trapped environment AE9/AP9/SPM at low Earth orbit

    NASA Astrophysics Data System (ADS)

    Badavi, Francis F.

    2014-09-01

    The completion of the international space station (ISS) in 2011 has provided the space research community an ideal proving ground for future long duration human activities in space. Ionizing radiation measurements in ISS form the ideal tool for the validation of radiation environmental models, nuclear transport codes and nuclear reaction cross sections. Indeed, prior measurements on the space transportation system (STS; shuttle) provided vital information impacting both the environmental models and the nuclear transport code developments by indicating the need for an improved dynamic model of the low Earth orbit (LEO) trapped environment. Additional studies using thermo-luminescent detector (TLD), tissue equivalent proportional counter (TEPC) area monitors, and computer aided design (CAD) model of earlier ISS configurations, confirmed STS observations that, as input, computational dosimetry requires an environmental model with dynamic and directional (anisotropic) behavior, as well as an accurate six degree of freedom (DOF) definition of the vehicle attitude and orientation along the orbit of ISS. At LEO, a vehicle encounters exposure from trapped particles and attenuated galactic cosmic rays (GCR). Within the trapped field, a challenge arises from properly estimating the amount of exposure acquired. There exist a number of models to define the intensities of the trapped particles during the solar quiet and active times. At active times, solar energetic particles (SEP) generated by solar flare or coronal mass ejection (CME) also contribute to the exposure at high northern and southern latitudes. Among the more established trapped models are the historic and popular AE8/AP8, dating back to the 1980s, the historic and less popular CRRES electron/proton, dating back to 1990s and the recently released AE9/AP9/SPM. The AE9/AP9/SPM model is a major improvement over the older AE8/AP8 and CRRES models. This model is derived from numerous measurements acquired over four solar cycles dating back to the 1970s, roughly representing 40 years of data collection. In contrast, the older AE8/AP8 and CRRES models were limited to only a few months of measurements taken during the prior solar minima and maxima. The dual goal of this paper is to first validate the AE8/AP8 and AE9/AP9/SPM trapped models against ISS dosemetric measurements for a silicon based detector, to assess the improvements in the AE9/AP9/SPM model as compared to AE8/AP8 model. The validation is done at selected target points within ISS-6A configuration during its passage through the south Atlantic anomaly (SAA). For such validation, only the isotropic spectrum of either model is needed. As a second goal, the isotropic spectra of both trapped models are re-casted into anisotropic spectra by modulating them with a measurement derived angular formalism which is applicable to trapped protons. Since at LEO electrons have minimal exposure contribution, the paper ignores the AE8 and AE9 component of the models and presents the angular validation of AP8 and AP9 against measurements from the compact environment anomaly sensor (CEASE) science instrument package, flown onboard the tri-service experiment-5 (TSX-5) satellite during the period of June 2000-July 2006. The spin stabilized satellite was flown in a 410 1710 km, 69 inclination orbit, allowing it to be exposed to a broad range of LEO regime. Particular emphasize is put on the validation of proton flux profiles at differential 40 MeV and integral >40 MeV, in the vicinity of SAA where protons exhibit east-west (EW) anisotropy and have a relatively narrow pitch angle distribution. Within SAA, the EW anisotropy results in different level of exposure to each side of CEASE instrument package, allowing the extraction of anisotropic proton spectra from the measurements. While the magnitude of the EW effect at LEO depends on a multitude of factors such as trapped proton energy, orientation of the spacecraft along the velocity vector and altitude of the spacecraft, for this part, the paper draws quantitative conclusions on t

  4. Silver Buckle Press Collection

    NSDL National Science Digital Library

    The University of Wisconsin's Digital Collections include everything from a tutorial in Icelandic to documents that tell the story of the Badger State's early settlement by Europeans. This particular collection brings together works by the Silver Buckle Press, which is a working museum of letterpress printing dedicated to preserving the craft of fine printing through educational programming, publications, exhibitions, and tours. The materials here include hard-to-find items from printing history, including "Hamilton's Wood Type" from 1901 and "The Nubian: a new fashion in types." This last work was created by the American Type Founders Company and it features "1928 Fashions in Type" with a focus on type faces that are "startling, eye-catching, attention-riveting and decidedly intriguing to the memory." There are over two dozen works in the collection, and visitors can search the complete text of all the items or just browse as they see fit. For students and lovers of graphic design, typography, advertising history, and related fields, this collection will be most enjoyable.

  5. Multipurpose active pixel sensor (APS)-based microtracker

    NASA Astrophysics Data System (ADS)

    Eisenman, Allan R.; Liebe, Carl C.; Zhu, David Q.

    1998-12-01

    A new, photon-sensitive, imaging array, the active pixel sensor (APS) has emerged as a competitor to the CCD imager for use in star and target trackers. The Jet Propulsion Laboratory (JPL) has undertaken a program to develop a new generation, highly integrated, APS-based, multipurpose tracker: the Programmable Intelligent Microtracker (PIM). The supporting hardware used in the PIM has been carefully selected to enhance the inherent advantages of the APS. Adequate computation power is included to perform star identification, star tracking, attitude determination, space docking, feature tracking, descent imaging for landing control, and target tracking capabilities. Its first version uses a JPL developed 256 X 256-pixel APS and an advanced 32-bit RISC microcontroller. By taking advantage of the unique features of the APS/microcontroller combination, the microtracker will achieve about an order-of-magnitude reduction in mass and power consumption compared to present state-of-the-art star trackers. It will also add the advantage of programmability to enable it to perform a variety of star, other celestial body, and target tracking tasks. The PIM is already proving the usefulness of its design concept for space applications. It is demonstrating the effectiveness of taking such an integrated approach in building a new generation of high performance, general purpose, tracking instruments to be applied to a large variety of future space missions.

  6. CD2AP Regulates SUMOylation of CIN85 in Podocytes

    PubMed Central

    Niedenthal, Rainer; Klaus, Malte; Teng, Beina; Worthmann, Kirstin; King, Benjamin L.; Peterson, Kevin J.; Haller, Hermann

    2012-01-01

    Podocytes are highly differentiated and polarized epithelial cells located on the visceral side of the glomerulus. They form an indispensable component of the glomerular filter, the slit diaphragm, formed by several transmembrane proteins and adaptor molecules. Disruption of the slit diaphragm can lead to massive proteinuria and nephrotic syndrome in mice and humans. CD2AP is an adaptor protein that is important for the maintenance of the slit diaphragm. Together with its paralogue, CIN85, CD2AP belongs to a family of adaptor proteins that are primarily described as being involved in endocytosis and downregulation of receptor tyrosine kinase activity. We have shown that full-length CIN85 is upregulated in podocytes in the absence of CD2AP, whereas in wild-type cells, full-length CIN85 is not detectable. In this study, we show that full-length CIN85 is postranslationally modified by SUMOylation in wild-type podocytes. We can demonstrate that CIN85 is SUMOylated by SUMO-1, -2, and -3 and that SUMOylation is enhanced in the presence of CD2AP. Conversion of lysine 598 to arginine completely abolishes SUMOylation and leads to increased binding of CIN85 to nephrin. Our results indicate a novel role for CD2AP in regulating posttranslational modification of CIN85. PMID:22203040

  7. The fundamental parameters of the Ap star 78 Virginis. Could 78 Vir be a rapidly oscillating Ap star?

    NASA Astrophysics Data System (ADS)

    Perraut, K.; Cunha, M.; Brando, I.; Loridat, J.; Mourard, D.; Meilland, A.; Nardetto, N.; McAlister, H.; ten Brummelaar, T. A.; Sturmann, J.; Sturmann, L.; Turner, N.; Farrington, C.; Vargas, N.

    2015-07-01

    Context. Determining the effective temperature of Ap stars, including the roAp stellar pulsators, is a difficult task owing to their strong magnetic field and their related spotted surfaces. It is, however, an important step towards constraining models of their complex atmosphere and testing proposed pulsation excitation mechanisms. Aims: Using the unique angular resolution provided by long-baseline visible interferometry, we aim at deriving accurate angular diameters of a number of Ap targets, so as to determine their unbiased effective temperature (Teff) and their accurate position in the Hertzsprung-Russell diagram, to estimate their mass and age, and to test non-adiabatic pulsation models. Interferometric results on four Ap stars have been published in earlier works. Here we report the results on a fifth, significantly hotter star. Methods: We observed 78 Vir with the visible spectrograph VEGA installed at the combined focus of the CHARA long-baseline optical array. We derived the limb-darkened diameter of this Ap star from our interferometric measurements. Based on photometric and spectroscopic data available in the literature, we estimated the star's bolometric flux and used it, in combination with its parallax and angular diameter, to determine the star's luminosity and effective temperature. We then used the derived fundamental parameters to perform a non-adiabatic pulsation analysis. Results: We determined a limb-darkened angular diameter of 0.346 0.006 mas and deduced a linear radius of R = 2.11 0.04 R?. Considering a bolometric flux of 2.73 0.20 10-7 erg/cm2/s we obtained a luminosity of L/L? = 27 2 and an effective temperature of Teff = 9100 190 K. The non-adiabatic pulsation modeling allows us to predict that high overtone pulsations could be excited in 78 Vir at frequencies ranging from 1.2 to 1.9 mHz, provided that the magnetic field is capable of suppressing envelope convection in the polar regions. Conclusions: Visible long-baseline interferometry is a unique means of deriving accurate fundamental parameters of Ap stars. The Ap star 78 Vir is found to be a promising roAp-star candidate and one that would allow us to extend recent tests on the roAp stars' excitation mechanism towards the blue edge of the instability strip. Asteroseismic data of this star would, therefore, be of strong interest. Based on observations made with the VEGA/CHARA spectro-interferometer.

  8. 28 CFR 540.64 - Press pools.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...PERSONS IN THE COMMUNITY Contact With News Media 540.64 Press pools...press pool, the Warden shall notify all news media representatives who have requested... (1) The national and international news services; (2) The television and...

  9. 28 CFR 540.64 - Press pools.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...PERSONS IN THE COMMUNITY Contact With News Media 540.64 Press pools...press pool, the Warden shall notify all news media representatives who have requested... (1) The national and international news services; (2) The television and...

  10. 28 CFR 540.64 - Press pools.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...PERSONS IN THE COMMUNITY Contact With News Media 540.64 Press pools...press pool, the Warden shall notify all news media representatives who have requested... (1) The national and international news services; (2) The television and...

  11. How to Press and Preserve Plants

    NSDL National Science Digital Library

    In this Biodiversity Counts activity, students learn how to press and preserve plant specimens. The online page includes illustrated instructions about how to layer and maintain pressings until the specimens have dried.

  12. Observations of pulsations in roAp stars

    E-print Network

    O. Kochukhov

    2007-02-09

    I review recent results of the observations of magnetoacoustic p-mode oscillations in roAp stars with the focus on time-resolved spectroscopic studies. Time-series spectroscopy of roAp stars reveals unexpected and diverse pulsational behaviour in the spectral lines of different chemical elements. These unique pulsational characteristics arise from an interplay between short vertical length of pulsation waves and extreme chemical stratification in the atmospheres of peculiar stars. This enables a tomographic reconstruction of the depth-dependence of chemical composition and pulsation wave properties. Combination of magnetoacoustic tomography with the Doppler imaging of the horizontal non-radial pulsation pattern opens possibility for an unprecedented three-dimensional mapping of roAp atmospheres.

  13. Pulsation in the atmosphere of roAp stars

    E-print Network

    O. Kochukhov

    2008-10-08

    High time resolution spectroscopy of roAp stars at large telescopes has led to a major breakthrough in our understanding of magnetoacoustic pulsations in these interesting objects. New observations have allowed to uncover a number of intricate relations between stellar oscillations, magnetic field, and chemical inhomogeneities. It is now understood that unusual pulsational characteristics of roAp stars arise from an interplay between short vertical length of pulsation waves and extreme chemical stratification. Here I review results of recent studies which utilize these unique properties to map 3D pulsation geometry using a combination of Doppler imaging, vertical pulsation tomography, interpretation of line profile variation, and ultraprecise space photometry. I also describe recent attempts to interpret theoretically the complex observational picture of roAp pulsations.

  14. Comprehensive management of hot-press hand injuries: long-term outcomes following reconstruction and rehabilitation.

    PubMed

    Hultman, Charles Scott; Erfanian, Kamil; Fraser, James; Thornton, Sydney J; Calvert, Catherine S; Cairns, Bruce A

    2010-05-01

    Hot-press hand injuries create significant challenges, in terms of acute coverage and restoration of function, and long-term outcomes are largely unknown. This article reviews the comprehensive management of hot-press hand injuries--which includes damage control procedures, resurfacing, reconstruction, and rehabilitation--and assesses outcomes such as return to work and final impairment ratings. We treated 56 patients with hot-press hand injuries, at a verified, accredited burn center in the Southeast between 1994 and 2008. Mechanism included laundry press (42 cases), industrial press (11 cases), and home appliance (3 cases). Mean burn size was 118 cm2, with 43 full-thickness and 13 partial thickness injuries. Mean follow-up was 17.7 months. During this 15-year period, 39 patients (70%) were admitted acutely (mean length of stay: 10.4 days), 48 patients (86%) required operative intervention, and 28 patients (50%) had secondary reconstruction, which included nerve decompression (11 cases), contracture release (11 cases), tendon procedures (11 cases), and joint repair (5 cases). Mean final impairment rating was 22%, with 38 patients (68%) returning to work. Hot-press hand burns can be devastating, but return to work is possible for most patients. We recommend early wound excision, aggressive perioperative hand therapy, low threshold for reconstructive procedures, and rehabilitative support. PMID:20395811

  15. Arte Pblico Press Receives Ford Foundation Grant

    E-print Network

    1989-04-01

    72 LATIN AMERICAN THEATRE REVIEW Arte Publico Press Receives Ford Foundation Grant Arte Pblico Press of the University of Houston has received a $133,426 grant from the Ford Foundation to publish an Hispanic Playwright Series. The two...-year grant is effective January 1,1989. The press will begin accepting play submissions for consideration immediately. Over the two-year period Arte Pblico Press will publish twelve collections of plays by U.S. Hispanics. Among the books planned...

  16. Power supply control units for APS ring magnets

    SciTech Connect

    Despe, O.D.

    1990-04-15

    The APS storage ring (1104 meters) is divided into 40 sectors. Each sector has 38 magnet coils in five magnet bases. Every alternate sector has an additional quadrupole magnet for skew correction. AR the main dipole magnets, two in each sector are connected in series and fed from one power supply unit. A base is controlled by one power supply control unit (PSCU). Each PSCU is connected to the host computer via a local area network (LAN). This note discusses the hardware configuration of the typical power supply control system used by the APS magnets and the software commands supported by the PSCU.

  17. Status of the Advanced Photon Source (APS) linear accelerator

    SciTech Connect

    White, M.; Arnold, N.; Berg, W.; Cours, A.; Fuja, R.; Grelick, A.; Ko, K.; Qian, Y.; Russell, T.; Sereno, N. [and others

    1994-09-01

    A 2856-MHz S-band, electron-positron linear accelerator (linac) has been constructed at the Advanced Photon Source (APS). It is the source of particles and the injector for the other APS accelerators, and linac commissioning is well underway. The linac is operated 24 hours per day to support linac beam studies and rf conditioning, as well as positron accumulator ring and synchrotron commissioning studies. The design goal for accelerated positron current is 8-mA, and has been met. Maximum positron energy to date is 420-MeV, approaching the design goal of 450-MeV. The linac design and its performance are discussed.

  18. The APS SASE FEL : status and commissioning results.

    SciTech Connect

    Milton, S. V.

    1999-04-20

    A self-amplified spontaneous emission (SASE) free-electron laser (FEL) is under construction at the Advanced Photon Source (APS). Three gun systems, an rf-test area, laser room, numerous diagnostics, a transfer line at the end of the linac, and a new building, which will serve as the experimental hall, have been added. The only remaining items to be installed are the undulators into the beamline. Here, the additions to the APS in support of this project as well as commissioning results and future plans will be discussed.

  19. The Princess and the Press

    NSDL National Science Digital Library

    After the tragic death of Princess Diana recently, there was much controversy over the role of the press as an intrusive force that helped lead to her demise. PBS Frontline, in a companion site to a recent TV documentary on the relationship between the English press and monarchy, examines this controversy in detail. Interviews with thirteen journalists, including Andrew Morton, who wrote a controversial biography of the late Princess; a transcript of Diana's Interview with the BBC in 1995; selected tabloid pictures and headlines; and a timeline illustrating British royalty encounters with the press are featured. A transcript of the show will be available shortly. As always, Frontline tackles controversial issues, and while some users may not agree with the tone or conclusions of the show (and site), there is a gold mine of information on the topic here.

  20. DESIGN AND OPERATION OF BELT FILTER PRESSES

    EPA Science Inventory

    Because early models of belt filter presses (developed from technology associated with the manufacture of paper) performed poorly, improved design and operation procedures for these presses were studied. Belt filter presses form part of a sludge dewatering system, and in terms of...

  1. The Small Book Press: A Cultural Essential.

    ERIC Educational Resources Information Center

    Henderson, Bill

    1984-01-01

    Discussion of small literary book publishers notes works of small-press authors (Thomas Paine, Washington Irving, Walt Whitman, Mark Twain, Upton Sinclair, Anais Nin); today's outstanding presses (Creative Arts Book Company, Persea Books, Full Court Press, Reed and Cannon Company, Tuumba Books); and role of little magazines. Thirty-seven

  2. Determining pressing rates for refractory semidry bodies

    Microsoft Academic Search

    V. E. Vernikovskii; A. P. Larin; S. A. Losev; S. A. Klass

    1971-01-01

    Conclusions An inverse relationship was established for the permitted pressing rate and the ratio between the volume of the products and its double perimeter in plan. With an increase in the dimensions of the article it is necessary to reduce the pressing rate to exclude the formation of pressing cracks.

  3. Exploring Mars: The Ares Payload Service (APS)

    NASA Astrophysics Data System (ADS)

    Bowen, Justin; Lusignan, Bruce

    1999-08-01

    In last year's Mars Society convention we introduced the results of five years of studies of space launch capability for the second millennium. We concluded that Single Stage to Orbit (SSTO) vehicles such as the Delta Clipper X33, and X34 cannot make it to orbit from the Earth's surface. Whether taking off vertically or horizontally or landing vertically or horizontally, the rocket equations, the performance of available fuels, and the realities of the weight and strength of materials leave no margin for payload. The promised savings from SSTO systems are illusory. However, a configuration that is able to deliver useful payload to orbit is the Single step to Orbit, SsTO, a rocket plane that is released fully fueled, from 35,000 to 40,000 feet altitude. Three approaches have been proposed. The Hot'l and Molnya Corporation designs carry the fueled rocket plane to altitude on the back of a carrier aircraft. In this design the carrier aircraft is Russia's Antonov 225 the world's largest cargo plane. The rocket plane is a modified version of the Buran, Russia's own space shuttle. Another configuration is Kelly Aviation's concept in which the fully fueled rocket plane is towed to altitude by the cargo plane and then released. A third approach is based on the early "X" planes, which were dropped from the belly of the carrier plane. While the rocket equations indicate that these three concepts can deliver useful payloads, the Stanford review found significant advantages to the approach of Pioneer Rocket, in which the rocket plane flies up to the carrier plane with conventional jet engines, docks, and then loads on the oxidizer for the flight to orbit. This architecture has more reasonable abort modes in case of system failure in either aircraft and can deliver a larger final payload to orbit for a given sized carrier. The Stanford recommendation is that the carrier aircraft be the Antonov 225. A design based on this was presented in a report last year. Refinements to the design notably an improved re-entry cooling system and fueling stability analysis were done this year. More technical detail and a proposed international consortium to develop the SSTO is presented in another session of this year's Mars convention. We believe that there will be no human exploration of Mars based on the Shuttle or Expendable launch vehicles, and no resources available except for a cooperative international program. However, just as the world is learning to cooperate in peacekeeping, we hold out the hope that similar cooperation will develop for Mars exploration. With that in mind, this year we asked the question- "How will the human mission get to Mars if it has to use the SsTO for transportation?"

  4. Exploring Mars: the Ares Payload Service (APS)

    NASA Technical Reports Server (NTRS)

    Bowen, Justin; Lusignan, Bruce

    1999-01-01

    In last year's Mars Society convention we introduced the results of five years of studies of space launch capability for the second millennium. We concluded that Single Stage to Orbit (SSTO) vehicles such as the Delta Clipper X33, and X34 cannot make it to orbit from the Earth's surface. Whether taking off vertically or horizontally or landing vertically or horizontally, the rocket equations, the performance of available fuels, and the realities of the weight and strength of materials leave no margin for payload. The promised savings from SSTO systems are illusory. However, a configuration that is able to deliver useful payload to orbit is the Single step to Orbit, SsTO, a rocket plane that is released fully fueled, from 35,000 to 40,000 feet altitude. Three approaches have been proposed. The Hot'l and Molnya Corporation designs carry the fueled rocket plane to altitude on the back of a carrier aircraft. In this design the carrier aircraft is Russia's Antonov 225 the world's largest cargo plane. The rocket plane is a modified version of the Buran, Russia's own space shuttle. Another configuration is Kelly Aviation's concept in which the fully fueled rocket plane is towed to altitude by the cargo plane and then released. A third approach is based on the early "X" planes, which were dropped from the belly of the carrier plane. While the rocket equations indicate that these three concepts can deliver useful payloads, the Stanford review found significant advantages to the approach of Pioneer Rocket, in which the rocket plane flies up to the carrier plane with conventional jet engines, docks, and then loads on the oxidizer for the flight to orbit. This architecture has more reasonable abort modes in case of system failure in either aircraft and can deliver a larger final payload to orbit for a given sized carrier. The Stanford recommendation is that the carrier aircraft be the Antonov 225. A design based on this was presented in a report last year. Refinements to the design notably an improved re-entry cooling system and fueling stability analysis were done this year. More technical detail and a proposed international consortium to develop the SSTO is presented in another session of this year's Mars convention. We believe that there will be no human exploration of Mars based on the Shuttle or Expendable launch vehicles, and no resources available except for a cooperative international program. However, just as the world is learning to cooperate in peacekeeping, we hold out the hope that similar cooperation will develop for Mars exploration. With that in mind, this year we asked the question- "How will the human mission get to Mars if it has to use the SsTO for transportation?"

  5. BEPO WIGNER ENERGY RELEASE

    Microsoft Academic Search

    J. L. Dickson; G. H. Kinchin; R. F. Jackson; W. M. Lomer; J. H. W. Simmonds

    1958-01-01

    The second Wigner energy release in the 6-Mw aircooled graphite-moderated research reactor BEPO was fully instrumented, and a preliminary analysis of the results shows the release to have been very complete. The reasons for the chosen method of release, the analysis and interpretation of the graphite sampling data from which the maximum anticipated release temperatures were predicted, and the various

  6. Effect of prostaglandin E? (PGE?) on the release of gonadotropin-releasing hormone (GnRH) from infundibular explants of cattle

    E-print Network

    Stephens, Tyler Paul

    2001-01-01

    and to a lesser extent FSH [25] . There are several putative neurochemicals involved in GnRH release. These are: the excitatory amino acids (glutamate and aspartate], melatonin, nitric oxide, norepinephrine, dopamine, serotonin, leptin, opiod... LD (ed. ), Nethods in Neuroendocrinology. London: CRC Press, Inc. 1992:69- 93. 39. Malven PV, Parfet JR, Gregg DW, Allrich RD, Noss GE. Relationships among concentrations of four opiod neuropeptides and luteinizing hormone-releasing hormone...

  7. 8 | NewScientist | 28 January 2012 RALPHWILSON/AP

    E-print Network

    Jackson, Robert B.

    8 | NewScientist | 28 January 2012 RALPHWILSON/AP Fracking is causing a furore in the US and Europe is scarce DRILLING INTO THE UNKNOWN SPECIALREPORT/FRACKING #12;28 January 2012 | NewScientist | 9 "Neighbours of new fracking operations complain of breathing difficulties and nausea" 100s of metres 1000s

  8. APS undulator and wiggler sources: Monte-Carlo simulation

    SciTech Connect

    Xu, S.L.; Lai, B.; Viccaro, P.J.

    1992-02-01

    Standard insertion devices will be provided to each sector by the Advanced Photon Source. It is important to define the radiation characteristics of these general purpose devices. In this document,results of Monte-Carlo simulation are presented. These results, based on the SHADOW program, include the APS Undulator A (UA), Wiggler A (WA), and Wiggler B (WB).

  9. Automated Procurement System (APS) revised project management plan (DS-03)

    NASA Technical Reports Server (NTRS)

    Murphy, Diane R.

    1995-01-01

    The Project Plan is the governing document for the implementation of the Automated Procurement System (APS). It includes a description of the proposed system, describes the work to be done, establishes a schedule of deliverables, and discusses the major standards and procedures to be followed.

  10. C-A/AP/#245 Electron gun for RHIC EBIS

    E-print Network

    C-A/AP/#245 July 2006 Electron gun for RHIC EBIS Alexander Pikin Collider-Accelerator Department Brookhaven National Laboratory Upton, NY 11973 #12;Electron gun for RHIC EBIS Alexander Pikin 1. Introduction The method of forming the electron beam in a new gun for RHIC EBIS is the same as is being used for a Test

  11. C-A/AP/#244 Pepper Pot Emittance Meter

    E-print Network

    C-A/AP/#244 July 2006 Pepper Pot Emittance Meter A. Pikin, A. Kponou, J. Ritter, V. Zajic Collider-Accelerator Department Brookhaven National Laboratory Upton, NY 11973 #12;Pepper pot emittance meter A. Pikin, A. Kponou primarily extracted from EBIS Test Stand, a new emittance meter has been designed and built. The motivation

  12. Accepted by ApJ. Periodicities in Solar Flare Occurrence

    E-print Network

    Bai, Taeil

    Accepted by ApJ. Periodicities in Solar Flare Occurrence: Analysis of Cycles 19­23 T. Bai Stanford University, Stanford, CA 94305 bai@quake.stanford.edu ABSTRACT Mid-range periodicities in solar flare spectra of major flare occurrence times for the time intervals analyzed by Ozguc & Atac and Bai, strongest

  13. APS/NIDDK Minority Travel Fellowship Awards Program

    NSDL National Science Digital Library

    APS Education Office (American Physiological Society Education Office)

    2012-04-01

    This article is on page 48 of The Physiologist, April 2012. Since its inception in 1987, the APS/NIDDK Minority Travel Fellowship Program has awarded more than 810 travel fellowships to over 555 undergraduate, graduate, and postdoctoral students and to faculty members at minority institutions.

  14. APS/DPP 111207-se 1 University Fusion Association Meeting

    E-print Network

    Grants and Solicitations ITER HEDLP Joint Program Plasma Science Issues and Plans #12;APS facilities rather than retaining the money for ITER and carrying it over to future fiscal years. Senate 7 Grants and Solicitations Theory Review complete, 44 applications submitted, 17 funded Sci

  15. ECE 572 Optoelectronics Instructor: A.P. DeFonzo

    E-print Network

    Massachusetts at Amherst, University of

    ECE 572 Optoelectronics Fall 2011 Instructor: A.P. DeFonzo Text: The Physics of Solar Cells Emitting Diode Power Generation Cell Characteristics Photons in , electrons Out: Basis Principles Electrons of photon effects Monocrystalline Devices Thin Film Devices Managing Light Beyond the Limits: High

  16. AP Biology Workshop: The Importance of Laboratory Work

    NSDL National Science Digital Library

    The College Board The College Board (The College Board; )

    2012-10-24

    This is a collection of essays that highlights the benefits of conducting lab experiments as part of the AP Biology curriculum. It encourages teachers to continue using learning tools like technology in lab experiments to enhance the classroom experience for students.

  17. Emission imaging of AP\\/HTPB propellant sandwich combustion

    Microsoft Academic Search

    B. T. Chorpening; M. Q. Brewster

    2002-01-01

    Ultraviolet emission imaging (305-315 nm) was used to study the combustion of sandwiches of ammonium perchlorate (AP) and hydroxyl-terminated polybutadiene (HTPB) in nitrogen at pressures up to 32 atm, with binder layers from 50 to 450 m in thickness. The emission imaging was combined with a novel backlighting technique to allow determination of the corresponding surface shape during combustion. The

  18. Introduction Anteroposterior (AP) patterning of the developing neural tube

    E-print Network

    Blumberg, Bruce

    2653 Introduction Anteroposterior (AP) patterning of the developing neural tube is a crucial early in Spemann's Organizer such as noggin, follistatin or chordin become neuralized in the absence of mesoderm., 1995; Xu et al., 1995) that normally acts to repress neural fate. Organizer-expressed neural inducing

  19. Integrating Particulate Representations into AP Chemistry and Introductory Chemistry Courses

    ERIC Educational Resources Information Center

    Prilliman, Stephen G.

    2014-01-01

    The College Board's recently revised curriculum for advanced placement (AP) chemistry places a strong emphasis on conceptual understanding, including representations of particle phenomena. This change in emphasis is informed by years of research showing that students could perform algorithmic calculations but not explain those calculations

  20. DETAIL VIEW OF WINCH USED TO RAISE AND LOWER AP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF WINCH USED TO RAISE AND LOWER AP 93W, ROOF LEVEL, PLATFORM D-SOUTH, HB-3, FACING WEST - Cape Canaveral Air Force Station, Launch Complex 39, Vehicle Assembly Building, VAB Road, East of Kennedy Parkway North, Cape Canaveral, Brevard County, FL

  1. Modeling Contaminants in AP-MS/MS Experiments

    PubMed Central

    Lavalle-Adam, Mathieu; Cloutier, Philippe; Coulombe, Benoit; Blanchette, Mathieu

    2015-01-01

    Identification of proteinprotein interactions (PPI) by affinity purification (AP) coupled with tandem mass spectrometry (AP-MS/MS) produces large data sets with high rates of false positives. This is in part because of contamination at the AP level (due to gel contamination, nonspecific binding to the TAP columns in the context of tandem affinity purification, insufficient purification, etc.). In this paper, we introduce a Bayesian approach to identify false-positive PPIs involving contaminants in AP-MS/MS experiments. Specifically, we propose a confidence assessment algorithm (called Decontaminator) that builds a model of contaminants using a small number of representative control experiments. It then uses this model to determine whether the Mascot score of a putative prey is significantly larger than what was observed in control experiments and assigns it a p-value and a false discovery rate. We show that our method identifies contaminants better than previously used approaches and results in a set of PPIs with a larger overlap with databases of known PPIs. Our approach will thus allow improved accuracy in PPI identification while reducing the number of control experiments required. PMID:21117706

  2. Validating Placement Rules for the APS Reading Test.

    ERIC Educational Resources Information Center

    College of the Canyons, Santa Clarita, CA.

    A study was conducted to determine how best to use APS Reading Test scores for making English placement recommendations for students at College of the Canyons (COC) in Santa Clarita, California. The primary method used to establish cut scores involves comparing success rates for contrasting groups over a range of scores. The contrasting groups are

  3. Nuclear Reactor Safety--The APS Submits its Report

    ERIC Educational Resources Information Center

    Physics Today, 1975

    1975-01-01

    Presents the summary section of the American Physical Society (APS) report on the safety features of the light-water reactor, reviews the design, construction, and operation of a reactor and outlines the primary engineered safety features. Summarizes the major recommendations of the study group. (GS)

  4. Transversal direct readout CMOS APS with variable shutter mode

    Microsoft Academic Search

    Shigehiro Miyatake; Masaru Miyamoto; Takashi Morimoto; Yasuo Masaki; Hideki Tanabe

    2002-01-01

    A transversal direct readout (TDR) structure for CMOS active pixel image sensors (APSs) eliminates the vertically striped fixed pattern noise. This novel architecture has evolved to incorporate a variable shutter mode as well as simplifying the pixel structure. This paper describes a 320 X 240- pixel TDR APS that not only exhibits neither vertically nor horizontally striped fixed pattern noise,

  5. CMOS APS imaging system application in star tracker

    Microsoft Academic Search

    Jie Li; Jinguo Liu; Xuekui Li; Yaxia Liu; Zhihang Hao

    2005-01-01

    Small satellites are capable of performing space explore missions that require accurate attitude determination and control. However, low weight, size, power and cost requirements limit the types of attitude sensor of small craft, such as CCD, are not practical for small satellites. CMOS APS is a good substitute for attitude sensors of small craft. Some of the technical advantages of

  6. CMOS APS crosstalk characterization via a unique submicron scanning system

    Microsoft Academic Search

    Igor Shcherback; Orly Yadid-Pecht

    2003-01-01

    This work introduces a novel way for CMOS APS crosstalk (CTK) determination and prediction based on our unique Submicron Scanning System (SSS) measurements. It enables the crosstalk magnitude determination, the tracking of its main causes, and can be used as a predictive tool for design optimization. A pronounced crosstalk asymmetry within the array which was revealed by the measurements is

  7. Bottom collection of photodiode-based CMOS APS

    Microsoft Academic Search

    B. Blanco-Filgueira; P. Lopez; D. Cabello; J. Ernst; H. Neubauer; J. Hauer

    2008-01-01

    The market for solid-state image sensors has been experiencing an explosive growth in recent years resulting in CMOS sensors rapidly becoming one of the emerging sectors with more projection potential in the semiconductors industry. A CMOS active pixel sensor (APS) with a reverse biased p-n junction photodiode constitutes the structure of more widespread use, and it has been made a

  8. A test structure for characterization of CMOS APS

    Microsoft Academic Search

    T. A. Elkhatib; S. Moussa; H. F. Ragaie; H. Haddara

    2003-01-01

    A test structure to characterize CMOS APS image sensor is presented. Individual photodiodes and pixels as well as an image sensor array of 6464 active pixels with selectable linear or logarithmic operation modes are designed. A test chip includes these features in addition to on-chip timing and control digital circuits as well as correlated double sampling have been built on

  9. APS storage ring vacuum chamber: Section 1, Evaluation

    SciTech Connect

    Benaroya, R.; Roop, B.

    1995-07-01

    The vacuum characteristics of the APS storage ring vacuum chamber prototype, Section One (S1), is presented. The base pressure achieved was 4 {times} 10{sup {minus}11}, the welds contained no virtual or real leaks, the NeG strip mounting design and activation procedures have been determined, and S1 was found contaminated with hydrocarbons.

  10. APS, April 2008 The Gluon's spin contribution to the

    E-print Network

    G. Bunce APS, April 2008 The Gluon's spin contribution to the proton's spin ---as seen at RHIC* I "proton spin crisis" #12; What else carries the proton spin ? Central question for the field. Orbital ang = + - = -+++ -+++ ^ ^^ , , Double longitudinal spin asymmetry ALL is sensitive to G #12; How: ---collide beams of protons

  11. Fuel Cell Application Problems: Study Guide for AP Chemistry

    NSDL National Science Digital Library

    Cox, Brian A.

    This study guide is intended for 10th-12th grade AP chemistry students studying fuel cell technology. Applicable National Science Education Standards are included in the document. The study guide includes a comparison of gasoline and hydrogen, a section on kinetic molecular theory, a section on electrochemistry and material on hydrogen fuel cells. This document may be downloaded in PDF file format.

  12. Approximate entropy (ApEn) as a complexity measure

    NASA Astrophysics Data System (ADS)

    Pincus, Steve

    1995-03-01

    Approximate entropy (ApEn) is a recently developed statistic quantifying regularity and complexity, which appears to have potential application to a wide variety of relatively short (greater than 100 points) and noisy time-series data. The development of ApEn was motivated by data length constraints commonly encountered, e.g., in heart rate, EEG, and endocrine hormone secretion data sets. We describe ApEn implementation and interpretation, indicating its utility to distinguish correlated stochastic processes, and composite deterministic/ stochastic models. We discuss the key technical idea that motivates ApEn, that one need not fully reconstruct an attractor to discriminate in a statistically valid mannermarginal probability distributions often suffice for this purpose. Finally, we discuss why algorithms to compute, e.g., correlation dimension and the Kolmogorov-Sinai (KS) entropy, often work well for true dynamical systems, yet sometimes operationally confound for general models, with the aid of visual representations of reconstructed dynamics for two contrasting processes.

  13. C A L I F O R N I A E N V I R O N M E N T A L P R O T E C T I O N A G E N C Y Press Release

    E-print Network

    recycling and reduction. Our departments are at the forefront of environmental science, using cutting-edge research to shape the state's environmental laws. # # # #12;Laningham (916) 3249670 State Releases Environmental Exposure Assessment Plan for Kettleman City Plan

  14. DOSSIER DE PRESSE Prix Brienne

    E-print Network

    van Tiggelen, Bart

    DOSSIER DE PRESSE Prix Brienne du Livre Gopolitique 2014 #12;2 2me Edition du Prix Brienne du Livre Gopolitique 2014 Jean-Yves Le Drian, Ministre de la Dfense, Prsident du jury, remettra le Prix du Prix Brienne. En rcompensant un auteur de gopolitique, l'instar de Franois Godement pour

  15. Gifted Education Press Quarterly, 1995.

    ERIC Educational Resources Information Center

    Fisher, Maurice D., Ed.

    1995-01-01

    This document consists of the four issues of the newsletter "Gifted Education Press Quarterly" published during 1995. This newsletter addresses issues in the education of gifted children and youth. The major articles are: (1) "Using Today's Technology: Parents Can Help Challenge Gifted Children" (Adrienne O'Neill); (2) "Outcomes-Based Education

  16. Book Editors IOS Press, 2003

    E-print Network

    Nourbakhsh, Illah

    of robots designed to interact with humans has increased in recent years, giving rise to the field of "human-robotBook Title Book Editors IOS Press, 2003 1 Long-Term Human-Robot Interaction: The Personal Nourbakhsha a Robotics Institute, Carnegie Mellon University b Learning Research and Development Center

  17. ARTICLE IN PRESS Pattern Recognition ( )

    E-print Network

    Kirzhner Valery

    ARTICLE IN PRESS Pattern Recognition ( ) www.elsevier.com/locate/patcog The method of N-grams on the comparison of vocabularies of N-grams. In contrast to the regular N-grams approach, the proposed N-grams method is based on calculation of imperfect occurrences of N-grams in a text up to a number of mismatched

  18. Book Editors IOS Press, 2003

    E-print Network

    Paris-Sud XI, Universit de

    Book Title Book Editors IOS Press, 2003 1 Quantify distinguishability in Robotics Aurlien Hazan a Complex Systems Laboratory (LSC) Abstract. Through a Dynamical Systems approach to robotics, we introduce a mea- sure of distinguishability between different behaviours of a robot, in an uncertain context

  19. Censorship and the Student Press.

    ERIC Educational Resources Information Center

    Oettinger, Lauren

    The First Amendment rights provided to journalists--freedom of speech and of the press--are fundamental beliefs held by Americans. What students learn in the government class, however, may not be what they learn as editors-in-chief of student newspapers. U.S. schools are being charged with the censorship of student publications at an

  20. Law and the Student Press.

    ERIC Educational Resources Information Center

    Stevens, George E.; Webster, John B.

    Court cases and legal decisions involving the student press in the late 1960s and early 1970s are brought together in this book in order to show how the law has been applied to school officials and student journalists in high school, college, and the underground. The ten chapters cover the following topics: censorship, libel, obscenity, contempt,

  1. LX10 and LX17 moisture content and release

    Microsoft Academic Search

    L. P. Rigdon; D. L. Seaton; A. J. Pane

    1984-01-01

    The results of four studies related to the moisture content, uptake, and release by two plastic-bonded explosives are reported. Formulations designated LX-10 and LX-17 were studied and are 95% HMX + 5% Viton A and 92.5% TATB + 7.5% Kel-F 800, respectively. Moisture content profiles for LX-17 following accelerated aging studies were obtained by analyzing dry machinings of pressed billets.

  2. Analysis of AP-1 function in cellular transformation pathways.

    PubMed Central

    Suzuki, T; Murakami, M; Onai, N; Fukuda, E; Hashimoto, Y; Sonobe, M H; Kameda, T; Ichinose, M; Miki, K; Iba, H

    1994-01-01

    To understand the role of endogenous AP-1 activity in cellular transformation induced by oncogenes, we have made use of a fos mutant (supfos-1) and a jun mutant (supjun-1), either of which can function as a transdominant inhibitor of AP-1-mediated transcriptional regulation. Chicken embryo fibroblasts (CEF) infected with a series of transforming retroviruses were doubly infected with retrovirus carrying supfos-1 or supjun-1, and suppression of cellular transformation was monitored in terms of reversion to normal cellular morphology or acquisition of anchorage-dependent growth. Cellular transformation induced by several exogenously expressed transforming genes of the fos or jun family was efficiently suppressed, as expected. CEF transformed by v-src, v-yes, v-fps, c-Ha-ras, and N-terminally truncated c-raf were also induced to revert to the normal phenotype by these transdominant mutants, suggesting that functional transcription factor AP-1 activity is essential for the cellular transformation induced by these oncogenes. The suppression is not attributable to nonspecific inhibition of cellular proliferation, because CEF transformed by v-ros or v-myc were not induced to revert to the normal phenotype. We next analyzed changes in all known components of chicken AP-1 induced by v-src, c-Ha-ras, or activated c-raf transformation. The levels of both Fra-2 and c-Jun expression were elevated two- to fourfold, and hyperphosphorylation of Fra-2 was also observed. We further showed that Fra-2-c-Jun heterodimer is mainly responsible for the elevated AP-1 DNA-binding activity in these transformed cells, and we propose that this heterodimer play a crucial role in the transformation induced by these oncogenes. Images PMID:8189491

  3. AP Theory IV: Intrinsic Topological Quantum Langlands Theory

    E-print Network

    H. E. Winkelnkemper

    2010-10-25

    Without using any moduli, sheaves, stacks, nor any analytic, nor category-type arguments, we exhibit an analogue to Geometric Langlands Theory in an entirely model-independent, non-perturbative,purely smooth topological context in Artin Presentation Theory. A basic initial feature is that AP Theory, as a whole, is already, ab initio, a universal canonical 2D sigma-model, targeting smooth, compact, simply-connected 4-manifolds with a connected boundary, and its topological Planckian quantum starting point, as well as its cone-like, infinitely-generated at each stage, graded group of homology-preserving, but topology-changing transitions/interactions, exhibit the most general qualitative S-duality. We first point out the numerous mathematically rigorous, model-free, (i.e., intrinsic), topological AP analogues with the heuristic Kapustin-Witten version of Geometric Langlands theory, as well as the crucial differences between the two theories. The latter have to exist since AP Theory deals, a priori, essentially only with discrete group-theoretic presentation theory, not Lie group representation theory, not with category nor moduli theory, does not need classical SUSY, nor Feynman integrals, lattice models, etc., and furthermore is model-independent and characteristic of real dimension four. It will become clear that AP Langlands theory is a model-independent, cone-like, graded, compact completion and topological 'envelope' of 4D N=4 SUSY YM theory, their starting point, anchored, kept in place, so to speak, by a purely discrete group-theoretic analogue of Donaldson/Seiberg-Witten theory. Due to its discrete group-theoretic conceptual simplicity and universality, the AP Langlands program should also be considered to be a new type of intrinsic model-free symmetry, a universal Erlanger Program for Modern Physics.

  4. APS beamline standard components handbook. Version 1.1

    SciTech Connect

    Kuzay, T.M.

    1992-01-01

    It is clear that most Advanced Photon Source (APS) Collaborative Access Team (CAT) members would like to concentrate on designing specialized equipment related to their scientific programs rather than on routine or standard beamline components. Thus, an effort is in progress at the APS to identify standard and modular components of APS beamlines. Identifying standard components is a nontrivial task because these components should support diverse beamline objectives. To assist with this effort, the APS has obtained advice and help from a Beamline Standardization and Modularization Committee consisting of experts in beamline design, construction, and operation. The staff of the Experimental Facilities Division identified various components thought to be standard items for beamlines, regardless of the specific scientific objective of a particular beamline. A generic beamline layout formed the basis for this identification. This layout is based on a double-crystal monochromator as the first optical element, with the possibility of other elements to follow. Pre-engineering designs were then made of the identified standard components. The Beamline Standardization and Modularization Committee has reviewed these designs and provided very useful input regarding the specifications of these components. We realize that there will be other configurations that may require special or modified components. This Handbook in its current version (1.1) contains descriptions, specifications, and pre-engineering design drawings of these standard components. In the future, the APS plans to add engineering drawings of identified standard beamline components. Use of standard components should result in major cost reductions for CATs in the areas of beamline design and construction.

  5. Chromosome localization of human genes for clathrin adaptor polypeptides AP2 beta and AP50 and the clathrin-binding protein, VCP.

    PubMed

    Druck, T; Gu, Y; Prabhala, G; Cannizzaro, L A; Park, S H; Huebner, K; Keen, J H

    1995-11-01

    Clathrin-coated vesicles, involved in endocytosis and Golgi processing, have a surface lattice containing clathrin triskelia and stoichiometric amounts of additional components termed "assembly proteins," or APs. The AP form at the plasma membrane, AP2, is composed of two large subunits of 100-115 kDa, denoted AP2 alpha and AP2 beta, a medium chain of 50 kDa, designated AP50, and a small chain. We have determined human chromosomal locations of genes for a large AP2 beta (CLAPB1) and a medium (CLAPM1) AP subunit and of a novel clathrin-binding protein, VCP, that binds clathrin simultaneously with APs. Chromosomal in situ hybridization of a human genomic clone demonstrated that the CLAPM1 gene mapped to chromosome region 3q28. The gene for the CLAPB1 large subunit was mapped to 17q11.2-q12 by PCR amplification of an AP2 beta fragment from a panel of rodent-human hybrid DNAs. To map the human VCP sequence, a human-specific probe was made by RT-PCR of human mRNA using oligonucleotide primers from conserved regions of the porcine sequence. The amplified human fragment served as probe on Southern blots of hybrid DNAs to determine that the human VCP locus maps to chromosome region 9pter-q34. PMID:8595912

  6. APS Presents Awards for the Best Physiology Project at Local Summer Science Camp

    NSDL National Science Digital Library

    APS Education Office (American Physiological Society Education Office)

    2012-10-01

    This article is on page 174-175 of The Physiologist, October 2012. APS members continue to judge and present Science Fair Awards on behalf of the APS at local and regional science fairs for precollege students across the nation.

  7. Tumour Necrosis Factor-? Regulates Human Eosinophil Apoptosis via Ligation of TNF-Receptor 1 and Balance between NF-?B and AP-1

    PubMed Central

    Kankaanranta, Hannu; Ilmarinen, Pinja; Zhang, Xianzhi; Adcock, Ian M.; Lahti, Aleksi; Barnes, Peter J.; Giembycz, Mark A.; Lindsay, Mark A.; Moilanen, Eeva

    2014-01-01

    Eosinophils play a central role in asthma. The present study was performed to investigate the effect of tumour necrosis factor-? (TNF-?) on longevity of isolated human eosinophils. In contrast to Fas, TNF-? inhibited eosinophil apoptosis as evidenced by a combination of flow cytometry, DNA fragmentation assay and morphological analyses. The effect of TNF-? on eosinophil apoptosis was reversed by a TNF-? neutralising antibody. The anti-apoptotic effect of TNF-? was not due to autocrine release of known survival-prolonging cytokines interleukins 3 and 5 or granulocyte-macrophage-colony-stimulating factor as their neutralisation did not affect the effect of TNF-?. The anti-apoptotic signal was mediated mainly by the TNF-receptor 1. TNF-? induced phosphorylation and degradation of I?B and an increase in NF-?B DNA-binding activity. The survival-prolonging effect of TNF-? was reversed by inhibitors of NF-?B pyrrolidinedithiocarbamate and gliotoxin and by an inhibitor of I?B kinase, BMS-345541. TNF-? induced also an increase in AP-1 DNA-binding activity and the antiapoptotic effect of TNF-? was potentiated by inhibitors of AP-1, SR 11302 and tanshinone IIA and by an inhibitor of c-jun-N-terminal kinase, SP600125, which is an upstream kinase activating AP-1. Our results thus suggest that TNF-? delays human eosinophil apoptosis via TNF-receptor 1 and the resulting changes in longevity depend on yin-yang balance between activation of NF-?B and AP-1. PMID:24587316

  8. Tumour growth and resistance to gemcitabine of pancreatic cancer cells are decreased by AP2? overexpression

    Microsoft Academic Search

    N Jonckheere; V Fauquette; L Stechly; N Saint-Laurent; S Aubert; C Susini; G Huet; N Porchet; I Van Seuningen; P Pigny

    2009-01-01

    Background:Activator protein-2? (AP-2?) is a transcription factor that belongs to the family of AP-2 proteins that have essential roles in tumorigenesis. Indeed, AP-2? is considered as a tumour-suppressor gene in different tissues such as colonic, prostatic or breast epithelial cells. Moreover, AP-2? also participates in the control of colon and breast cancer cells sensitivity towards chemotherapeutic drugs. Despite its potential

  9. Neural tube, skeletal and body wall defects in mice lacking transcription factor AP2

    Microsoft Academic Search

    Jian Zhang; Stephanie Hagopian-Donaldson; George Serbedzija; Jennifer Elsemore; Debora Plehn-Dujowich; Andrew P. McMahon; Richard A. Flavell; Trevor Williams

    1996-01-01

    THE retinoic acid-inducible transcription factor AP-2 is expressed in epithelial and neural crest cell lineages during murine development1-5. AP-2 can regulate neural and epithelial gene transcription, and is associated with overexpression of c-erbB-2 in human breast-cancer cell lines4-6. To ascertain the importance of AP-2 for normal development, we have derived mice containing a homozygous disruption of the AP-2 gene. These

  10. AP STAR AWARDS Who is the shining star in your department?

    E-print Network

    AP STAR AWARDS Who is the shining star in your department? Give them the honor they deserve! Deadline for application is February 4, 2011 The AP Stars award was created to express appreciation professionals on campus? Previous AP Stars recipients are not eligible to win again for two (2) years after

  11. College Completion: Comparing AP, Dual-Enrolled, and Nonadvanced Students. Research Report 2014-3

    ERIC Educational Resources Information Center

    Godfrey, Kelly; Matos-Elefonte, Haifa; Ewing, Maureen; Patel, Priyank

    2014-01-01

    The study presented here is an investigation and comparison of the relationships between the Advanced Placement Program (AP) and dual-enrolled high school courses and college outcomes. Previous research provides evidence that participation in AP, and subsequent success on AP Exams, is positively related to various college outcomes including an

  12. AP Studio Art as an Enabling Constraint for Secondary Art Education

    ERIC Educational Resources Information Center

    Graham, Mark A.

    2009-01-01

    Advanced Placement (AP) Studio Art is an influential force in secondary art education as is evident in the 31,800 portfolios submitted for review in 2008. From the perspectives of a high school educator and AP Reader, this author has observed how the constraints of the AP program can be used to generate support for high school art programs and

  13. Outsourcing Home AP Management to the Cloud through an Open API

    E-print Network

    Banerjee, Suman

    the most common among home devices today are wireless Access Points (APs) that are supplied by a number of diverse vendors -- Linksys, Netgear, DLink, TrendNet, Belkin, to name a few. In fact, wireless APs be implemented by home wireless APs to enable a cloud-based management service that enables coordination

  14. Implementation and Testing of Fault-Tolerant Photodiode-based Active Pixel Sensor (APS)

    E-print Network

    Chapman, Glenn H.

    -tolerant photodiode APS was designed and fabricated using a CMOS 0.18m process. Testing included both fully. This paper expands on the previous work by implementing the redundant photodiode APS in a CMOS 0.18m processImplementation and Testing of Fault-Tolerant Photodiode-based Active Pixel Sensor (APS) Sunjaya

  15. CMOS APS PHOTORESPONSE AND CROSSTALK OPTIMIZATION ANALYSIS FOR SCALABLE CMOS TECHNOLOGIES

    E-print Network

    1 CMOS APS PHOTORESPONSE AND CROSSTALK OPTIMIZATION ANALYSIS FOR SCALABLE CMOS TECHNOLOGIES Igor developed for photoresponse estimation of a photodiode based CMOS Active Pixel Sensor (APS). We show its use for maximum pixel photosignal prediction and CMOS APS crosstalk (CTK) optimization. Our model reveals

  16. CMOS APS crosstalk characterization via a unique Sub-micron Scanning System

    E-print Network

    CMOS APS crosstalk characterization via a unique Sub-micron Scanning System Igor Shcherback, Orly introduces a novel way for CMOS APS crosstalk (CTK) determination and prediction based on our unique Sub out that CMOS APS crosstalk is mostly affected by the specific pixel architecture and the pixels

  17. Analysis of Temporal Noise in CMOS APS Hui Tian, Boyd Fowler, and Abbas El Gamal

    E-print Network

    El Gamal, Abbas

    Analysis of Temporal Noise in CMOS APS Hui Tian, Boyd Fowler, and Abbas El Gamal Information shot noise and the thermal and 1/f noise of the output charge to voltage amplifier. In a CMOS APS of the APS charge to voltage characteristics, which is becoming more pronounced as CMOS technology scales

  18. Characteristics of Fault-Tolerant Photodiode and Photogate Active Pixel Sensor (APS)

    E-print Network

    Chapman, Glenn H.

    tolerant APS design has been implemented in a 0.18m CMOS process for both a photodiode based and photogate compatibility with the standard CMOS process, the ability to integrate other components with the APS, a single the design and testing of a fault-tolerant APS using a photogate fabricated in a 0.18m CMOS process as well

  19. Analysis of 1/f noise in CMOS APS Hui Tian, and Abbas El Gamal

    E-print Network

    El Gamal, Abbas

    Analysis of 1/f noise in CMOS APS Hui Tian, and Abbas El Gamal Information Systems Laboratory is used to analyze the effect of 1/f noise due to pixel level transistors in a CMOS APS. The results show noise, subthreshold operation, nonstationary 1/f noise model, time domain noise analysis, CMOS APS

  20. APS: 125 Years of Progress of Physiology as a Scientific Discipline and a Profession

    ERIC Educational Resources Information Center

    Carroll, Robert G.; Frank, Martin; Ra'anan, Alice; Matyas, Marsha L.

    2013-01-01

    The Experimental Biology 2012 meeting in San Diego, CA, included events to celebrate the 125th anniversary of the founding of the American Physiological Society (APS) and reflect on the recent accomplishments of the society. Most of the APS activities in the past quarter century were guided by a series of strategic plans. Membership in the APS

  1. A&P Job Title Job Code Search Required? Applications Programmer 2512 No

    E-print Network

    Wu, Shin-Tson

    A&P Job Title Job Code Search Required? Applications Programmer 2512 No Applications Systems No #12;A&P Job Title Job Code Search Required? Assistant Director Educational Technology 9404 No Associate Director Physical Plant 9354 No Associate Director Purchasing 9326 No #12;A&P Job Title Job Code

  2. A comparison of impulse drying to double felted pressing on pilot- scale shoe presses and roll presses. Progress report, No. 6

    SciTech Connect

    Orloff, D.I.

    1992-08-01

    Pilot-scale shoe press and roll press experiments have been conducted to compare impulse drying and double felted pressing. Both ceramic coated and Beloit Type C press rolls have been evaluated. The experiments show that impulse drying can provide significantly higher outgoing solids than double felled pressing at the same impulse. For example, at an impulse of 0.234 MPa seconds (34 psi seconds), sheets at an ingoing solids of 52% were impulse dried (using the Beloit Type C press roll) to 68% solids while optimized double felled pressing could only yield press dryness of, at most, 60%.

  3. Diadenosine polyphosphates (Ap3A and Ap4A) behave as alarmones triggering the synthesis of enzymes of the phenylpropanoid pathway in Arabidopsis thaliana

    PubMed Central

    Pietrowska-Borek, Ma?gorzata; Nuc, Katarzyna; Zielezi?ska, Ma?gorzata; Guranowski, Andrzej

    2011-01-01

    It is known that cells under stress accumulate various dinucleoside polyphosphates, compounds suggested to function as alarmones. In plants, the phenylpropanoid pathways yield metabolites protecting these organisms against various types of stress. Observations reported in this communication link these two phenomena and provide an example of a metabolic addressee for an alarm signaled by diadenosine triphosphate (Ap3A) or diadenosine tetraphosphate (Ap4A). In response to added Ap3A or Ap4A, seedlings of Arabidopsis thaliana incubated in full nutrition medium increased both the expression of the genes for and the specific activity of phenylalanine ammonia-lyase and 4-coumarate:coenzyme A ligase, enzymes that control the beginning of the phenylpropanoid pathway. Neither adenine mononucleotides (AMP, ADP or ATP) nor adenosine evoked such effects. Reactions catalyzed in vitro by these enzymes were not affected by Ap3A or Ap4A. PMID:23650569

  4. [Effect of diadenosine oligophosphates (Ap4A and Ap3A) and their phosphonate analogs on catalytic properties of phenylalanyl-tRNA synthetase from E. coli].

    PubMed

    Biriukov, A P; Zakharova, O D; Lavrik, O I

    1987-09-01

    The influence of P1,P3-bis(5'-adenosyl)triphosphate (Ap3A), P1,P4-bis(5'-adenosyl)tetraphosphate (Ap4A) and its analogues, containing a residue of methylenediphosphonic acid in various positions of the oligophosphate chain, on the reactions catalysed by phenylalanyl-tRNA synthetase from E. coli MRE-600 has been studied. The compounds do not affect significantly the rate of ATP-[32P]PPi-exchange nor maintain this reaction in the absence of ATP. The diadenosineoligophosphates are shown to be noncompetitive inhibitors of ATP in the tRNA aminoacylation by phenylalanine (for Ap4A Ki = 1,45.10(-3) M). The phosphonate analogues of Ap4A inhibit the synthesis of Ap3A depending on their structure. The conclusion is thus drawn that the E. coli MRE-600 phenylalanyl-tRNA synthetase does not interact property with Ap4A and its phosphonate analogues. PMID:3322289

  5. Relationship between major geophysical events and the planetary magnetic Ap index, from 1844 to the present

    NASA Astrophysics Data System (ADS)

    Casati, Michele; Straser, Valentino

    2015-04-01

    In this study, for the first time, we compared the annual magnetic Ap index, taken from original sources, from 1844 to the present day [Svalgaard,2014], with: i) sixteen large volcanic eruptions of index VEI5 + recorded by, Smithsonian Institute (Global Volcanism Program), ii) three sets of the volcanic aerosols data [Ammann et.al, 2003][Gao;Chaochao;Alan Robock;Caspar Ammann,2008][Traufetter et.al,2004] and iii) eight major earthquakes of a magnitude between 8.7Ap index. Specifically, in the downward phase of the planetary Ap index, under the annual value of 7 or, in the phase when the annual value exceeded 22. We identified a total of 14 transitions (eight in the solar minimum and six in the solar maxima) each with a period of about two and a half years making a total of almost 35 years of activity during the 169 years under review. During the 14 transitions 18 of the 24 major historical geophysical events occurred from 1844 to the present. Analysis of data shows a clear link between the electromagnetic (EM) dynamics recorded in large historical solar minima (Maunder, Dalton or solar minimum 1880-1920), the large solar maxima (solar cycles 19, 21 & 22) and the energy released during large geophysical events [Casati,2014]. The physical process of solar-terrestrial interaction, also reveal a deep and intrinsic relationship between the EM dynamics of the inner solar system and the temporal occurrence of major geophysical events. The references in scientific literature, in support of this work, are numerous: from empirical evidence, that we find in the late nineteenth century - early twentieth century, to more recent references. Some of which are: [Casey,2010][Charvtov, 2010][Choi, 2010][Duma; Vilardo, 1998][Khachikyan et al,2014][Kolvankar,2008][Kovalyov,2014][Mazzarella;Palumbo,1989][Stothers,1989][St?etik,2003][Sytinsky,1987 ,1989, 1998].

  6. Expanded Analysis of Hot Isostatic Pressed Iodine-Loaded Silver-Exchanged Mordenite

    SciTech Connect

    Jubin, R. T. [ORNL; Bruffey, S. H. [ORNL; Patton, K. K. [ORNL

    2014-09-30

    Reduced silver-exchanged mordenite (Ag0Z) is being evaluated as a potential material to control the release of radioactive iodine that is released during the reprocessing of used nuclear fuel into the plant off-gas streams. The purpose of this study was to determine if hot pressing could directly convert this iodine loaded sorbent into a waste form suitable for long-term disposition. The minimal pretreatment required for production of pressed pellets makes hot pressing a technically and economically desirable process. Initial scoping studies utilized hot uniaxial pressing (HUPing) to prepare samples of non-iodine-loaded reduced silver exchanged mordenite (Ag0Z). The resulting samples were very fragile due to the low pressure (~ 28 MPa) used. It was recommended that hot isostatic pressing (HIPing), performed at higher temperatures and pressures, be investigated. HIPing was carried out in two phases, with a third and final phase currently underway. Phase I evaluated the effects of pressure and temperature conditions on the manufacture of a pressed sample. The base material was an engineered form of silver zeolite. Six samples of Ag0Z and two samples of I-Ag0Z were pressed. It was found that HIPing produced a pressed pellet of high density. Analysis of each pressed pellet by scanning electron microscopy-energy dispersive spectrophotometry (SEM-EDS) and X-ray diffraction (XRD) demonstrated that under the conditions used for pressing, the majority of the material transforms into an amorphous structure. The only crystalline phase observed in the pressed Ag0Z material was SiO2. For the samples loaded with iodine (I-Ag0Z) iodine was present as AgI clusters at low temperatures, and transformed into AgIO4 at high temperatures. Surface mapping and EDS demonstrate segregation between silver iodide phases and silicon dioxide phases. Based on the results of the Phase I study, an expanded test matrix was developed to examine the effects of multiple source materials, compositional variations, and an expanded temperature range. Each sample was analyzed with the approach used in Phase I. In all cases, there is nothing in the SEM or XRD analyses that indicates creation of any AgI-containing silicon phase, with the samples being found to be largely amorphous. Phase III of this study has been initiated and is the final phase of scoping tests. It will expand upon the test matrix completed in Phase II and will examine the durability of the pressed pellets through product consistency testing (PCT) studies. Transformation of the component material into a well-characterized iodine-containing mineral phase would be desirable. This would limit the additional experimental testing and modeling required to determine the long-term stability of the pressed pellet, as much of that information has already been learned for several common iodine-containing minerals. However, this is not an absolute requirement, especially if pellets produced by hot isostatic pressing can be demonstrated through initial PCT studies to retain iodine well despite their amorphous composition.

  7. ?-1 Receptor agonist SKF10047 inhibits glutamate release in rat cerebral cortex nerve endings.

    PubMed

    Lu, Cheng-Wei; Lin, Tzu-Yu; Wang, Chia-Chuan; Wang, Su-Jane

    2012-05-01

    ?-1 Receptors are expressed in the brain, and their activation has been shown to prevent neuronal death associated with glutamate toxicity. This study investigates the possible mechanism and effect of [2S-(2?,6?,11R*]-1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(2-propenyl)-2,6-methano-3-benzazocin-8-ol (SKF10047), a ?-1 receptor agonist, on endogenous glutamate release in the nerve terminals of rat cerebral cortex. Results show that SKF10047 inhibited the release of glutamate evoked by the K? channel blocker 4-aminopyridine (4-AP), and the ?-1 receptor antagonist N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine (BD1047) blocked this phenomenon. The effects of SKF10047 on the evoked glutamate release were prevented by the chelating extracellular Ca?ions and the vesicular transporter inhibitor bafilomycin A1. However, the glutamate transporter inhibitor DL-threo-?-benzyl-oxyaspartate did not have any effect on the action of SKF10047. SKF10047 decreased the depolarization-induced increase in the cytosolic free Ca? concentration ([Ca?](C)), but did not alter 4-AP-mediated depolarization. Furthermore, the effects of SKF10047 on evoked glutamate release were prevented by blocking the Ca(v)2.2 (N-type) and Ca(v)2.1 (P/Q-type) channels, but not by blocking the ryanodine receptors or the mitochondrial Na?/Ca? exchange. In addition, conventional protein kinase C (PKC) inhibitors abolished the SKF10047 effect on 4-AP-evoked glutamate release. Western blot analyses showed that SKF10047 decreased the 4-AP-induced phosphorylation of PKC and PKC?. These results show that ?-1 receptor activation inhibits glutamate release from rat cortical nerve terminals. This effect is linked to a decrease in [Ca?](C) caused by Ca? entry through presynaptic voltage-dependent Ca? channels and the suppression of the PKC signaling cascade. PMID:22357973

  8. Structural characterization of the N-terminal mineral modification domains from the molluscan crystal-modulating biomineralization proteins, AP7 and AP24.

    PubMed

    Wustman, Brandon A; Morse, Daniel E; Evans, John Spencer

    2004-08-01

    The AP7 and AP24 proteins represent a class of mineral-interaction polypeptides that are found in the aragonite-containing nacre layer of mollusk shell (H. rufescens). These proteins have been shown to preferentially interfere with calcium carbonate mineral growth in vitro. It is believed that both proteins play an important role in aragonite polymorph selection in the mollusk shell. Previously, we demonstrated the 1-30 amino acid (AA) N-terminal sequences of AP7 and AP24 represent mineral interaction/modification domains in both proteins, as evidenced by their ability to frustrate calcium carbonate crystal growth at step edge regions. In this present report, using free N-terminal, C(alpha)-amide "capped" synthetic polypeptides representing the 1-30 AA regions of AP7 (AP7-1 polypeptide) and AP24 (AP24-1 polypeptide) and NMR spectroscopy, we confirm that both N-terminal sequences possess putative Ca (II) interaction polyanionic sequence regions (2 x -DD- in AP7-1, -DDDED- in AP24-1) that are random coil-like in structure. However, with regard to the remaining sequences regions, each polypeptide features unique structural differences. AP7-1 possesses an extended beta-strand or polyproline type II-like structure within the A11-M10, S12-V13, and S28-I27 sequence regions, with the remaining sequence regions adopting a random-coil-like structure, a trait common to other polyelectrolyte mineral-associated polypeptide sequences. Conversely, AP24-1 possesses random coil-like structure within A1-S9 and Q14-N16 sequence regions, and evidence for turn-like, bend, or loop conformation within the G10-N13, Q17-N24, and M29-F30 sequence regions, similar to the structures identified within the putative elastomeric proteins Lustrin A and sea urchin spicule matrix proteins. The similarities and differences in AP7 and AP24 N-terminal domain structure are discussed with regard to joint AP7-AP24 protein modification of calcium carbonate growth. PMID:15222016

  9. Time resolved spectroscopy of the cool Ap star HD 213637*

    NASA Astrophysics Data System (ADS)

    Elkin, V. G.; Kurtz, D. W.; Mathys, G.

    2015-02-01

    We present an analysis of high time resolution spectra of the chemically peculiar Ap star HD 213637. The star shows rapid radial velocity variations with a period close to the photometric pulsation period. Radial velocity pulsation amplitudes vary significantly for different rare earth elements. The highest pulsation amplitudes belong to lines of Tb III (360 m s-1), Pr II (250 m s-1) and Pr III (230 m s-1). We did not detect any pulsations from spectral lines of Eu II and in H?, in contrast to many other roAp stars. We also did not find radial velocity pulsations using spectral lines of other chemical elements, including Mg, Si, Ca, Sc, Cr, Fe, Ni, Y and Ba. There are phase shifts between the maxima of pulsation amplitudes of different rare earth elements and ions, which is evidence of an outwardly running magneto-acoustic wave propagating through the upper stellar atmosphere.

  10. Airborne Precision Spacing (APS) Dependent Parallel Arrivals (DPA)

    NASA Technical Reports Server (NTRS)

    Smith, Colin L.

    2012-01-01

    The Airborne Precision Spacing (APS) team at the NASA Langley Research Center (LaRC) has been developing a concept of operations to extend the current APS concept to support dependent approaches to parallel or converging runways along with the required pilot and controller procedures and pilot interfaces. A staggered operations capability for the Airborne Spacing for Terminal Arrival Routes (ASTAR) tool was developed and designated as ASTAR10. ASTAR10 has reached a sufficient level of maturity to be validated and tested through a fast-time simulation. The purpose of the experiment was to identify and resolve any remaining issues in the ASTAR10 algorithm, as well as put the concept of operations through a practical test.

  11. APS/ESRF/SPring-8 2008 three-way meeting.

    SciTech Connect

    Davey, S.; APS Engineering Support Division

    2008-07-01

    To foster scientific collaborations among the Advanced Photon Source (APS), the European Synchrotron Radiation Facility (ESRF), and the Super Photon Ring-8 GeV (SPring-8), the three facilities meet on a regular basis to hold technical discussions on accelerator and beamline topics and management and operational issues of common interest. The 2008 Three-Way Meeting (3WM) was held on March 18-19 at the APS with more than 20 representatives from each facility. Satellite workshops were also held on the topics of X-ray Optics, Nanoscience with X-rays, User Services, and Accelerator R&D. The 3WM and satellite workshops served as platforms for presentations and discussions of new and exciting developments at the three synchrotron sources.

  12. Impedance studies - Part 4: The APS impedance budget

    SciTech Connect

    NONE

    1988-07-01

    This note will wrap up the numerical results that were obtained in our calculations of the wake potentials, the loss factors, and the impedances for a variety of structures in the APS storage ring. It consists of five sections and one appendix. Section 1 is an introduction. Section 2 summarizes the hand calculations. The computer calculations are the subject 1 of Section 3. Section 4 discusses several tests in our numerical methods. Section 5 presents the APS impedance budget, along with some discussion. The appendix contains the figures of the structures, the longitudinal/transverse wake potentials and the real/imaginary part of the impedances of various sorts of geometries that have been included in the budget.

  13. Tank 241-AP-107 tank characterization plan. Revision 1

    SciTech Connect

    Schreiber, R.D. [Westinghouse Hanford Co., Richland, WA (United States)

    1995-01-20

    Defense Nuclear Facilities Safety Board has directed the DOE to concentrate ear-term sampling and analysis activities on identification and resolution of issues (Conway 1993). The Data Quality Objective (DQO) process was chosen as a tool to be used in the resolution of safety issues. As a result, a revision in the Federal Facilities Agreement and Consent Order (Tri-Party Agreement) milestone M-44-00 has been made, which states that ``A Tank Characterization Plan (TCP) will be developed for each double-shell tank (DST) and single-shell tank (SST) using the DQO process; Development of TCPs by the DQO process is intended to allow users (e.g., Hanford Facility user groups, regulators) to ensure their needs will be met and that resources are devoted to gaining only necessary information.`` This document satisfies that requirement for the tank 241-AP-107 (AP-107).

  14. Real-time orbit feedback at the APS.

    SciTech Connect

    Carwardine, J.

    1998-06-18

    A real-time orbit feedback system has been implemented at the Advanced Photon Source in order to meet the stringent orbit stability requirements. The system reduces global orbit motion below 30Hz by a factor of four to below 5{micro}m rms horizontally and 2{micro}m rms vertically. This paper focuses on dynamic orbit stability and describes the all-digital orbit feedback system that has been implemented at the APS. Implementation of the global orbit feedback system is described and its latest performance is presented. Ultimately, the system will provide local feedback at each x-ray source point using installed photon BPMs to measure x-ray beam position and angle directly. Technical challenges associated with local feedback and with dynamics of the associated corrector magnets are described. The unique diagnostic capabilities provided by the APS system are discussed with reference to their use in identifying sources of the underlying orbit motion.

  15. Status of APS 1-Mwe Parabolic Trough Project

    SciTech Connect

    Canada, S.; Brosseau, D.; Kolb, G.; Moore, L.; Cable, R.; Price, H.

    2005-11-01

    Arizona Public Service (APS) is currently installing new power facilities to generate a portion of its electricity from solar resources that will satisfy its obligation under the Arizona Environmental Portfolio Standard (EPS). During FY04, APS began construction on a 1-MWe parabolic trough concentrating solar power plant. This plant represents the first parabolic trough plant to begin construction since 1991. Site preparation and construction activities continued throughout much of FY05, and startup activities are planned for Fall 2005 (with completion early in FY06). The plant will be the first commercial deployment of the Solargenix parabolic trough collector technology developed under contract to the National Renewable Energy Laboratory. The plant will use an organic Rankine cycle (ORC) power plant, provided by Ormat. The ORC power plant is much simpler than the conventional steam Rankine cycle plant and allows unattended operation of the facility.

  16. FBI releases carnivore documents

    Microsoft Academic Search

    Wayne Madsen

    2000-01-01

    Documents released to the Electronic Privacy Information Center (EPIC) on 2 October 2000 by the Federal Bureau of Investigation (FBI) shed some new light on the technical genesis of the Carnivore Internet collection system. The release of the documents follow a lawsuit brought against the FBI by EPIC following a refusal to release them under the Freedom of Information Act.

  17. Hot isostatic pressing of ceramics

    NASA Technical Reports Server (NTRS)

    Honma, K.

    1985-01-01

    A mixture containing glass 70 to 95 and BN or B4C powder (0.1-10 microns) 5 to 30 vol. % is used as a secondary pressure medium in hot isostatic pressing of ceramics. Thus, Pyrex beads were mixed with 15% vol. BN powder (average diameter 2 microns), fused at 1400 deg for 2 h, cooled, crushed, and put into a graphite crucible. A Si3N4 sintered body was embedded in the powder, heated in vacuum at 1200 deg for 2 h, treated in a hot isostatic press furnace at 1700 deg and 1000 atm. for 1 h, and cooled to give a Si3N4 ceramic. It was easily separated from the crucible.

  18. Isotopic anomaly and stratification of Ca in magnetic Ap stars

    E-print Network

    T. Ryabchikova; O. Kochukhov; S. Bagnulo

    2008-01-15

    We have carried out an accurate investigation of the Ca isotopic composition and stratification in the atmospheres of 23 magnetic chemically peculiar (Ap) stars of different temperature and magnetic field strength. With the UVES spectrograph at the 8m ESO VLT, we have obtained high-resolution spectra of Ap stars in the wavelength range 3000-10000 A. Using a detailed spectrum synthesis calculations, we have reproduced a variety of Ca lines in the optical and ultraviolet spectral regions, inferring the overall vertical distribution of Ca abundance, then we have deduced the relative isotopic composition and its dependence on height using the profile of the the IR-triplet Ca II line at lambda 8498 A. In 22 out of 23 studied stars, we found that Ca is strongly stratified, being usually overabundant by 1.0-1.5 dex below log tau_5000 ~ -1, and strongly depleted above log tau_5000 = -1.5. The IR-triplet Ca II line at lambda 8498 A reveals a significant contribution of the heavy isotopes 46Ca and 48Ca, which represent less than 1% of the terrestrial Ca isotopic mixture. We confirm our previous finding that the presence of heavy Ca isotopes is generally anticorrelated with the magnetic field strength. Moreover, we discover that in Ap stars with relatively small surface magnetic fields (atmospheric layers. This vertical isotopic separation, observed for the first time for any metal in a stellar atmosphere, disappears in stars with magnetic field strength above 6-7 kG. We suggest that the overall Ca stratification and depth-dependent isotopic anomaly observed in Ap stars may be attributed to a combined action of the radiatively-driven diffusion and light-induced drift.

  19. Linking radio and gamma-ray emission in Ap Librae

    NASA Astrophysics Data System (ADS)

    Hervet, O.; Boisson, C.; Sol, H.

    2015-06-01

    Ap Lib is one of the rare low-synchrotron-peaked blazars detected so far at TeV energies. This type of source is not properly modelled by standard one-zone leptonic synchrotron self-Compton (SSC) emission scenarios. The aim of this paper is to study the relevance of additional components that should naturally occur in an SSC scenario for a better understanding of the emission mechanisms, especially at very high energies (VHE). We use simultaneous data from a multi-wavelength campaign of the Planck, Swift-UVOT, and Swift-XRT telescopes carried out in February 2010, as well as quasi-simultaneous data of WISE, Fermi, and HESS taken in 2010. The multi-lambda emission of Ap Lib is modelled by a blob-in-jet SSC scenario including the contribution of the base of the VLBI-extended jet, the radiative blob-jet interaction, the accretion disk, and its associated external photon field. We show that signatures of a strong parsec-scale jet and of an accretion disk emission are present in the spectral energy distribution. We can link the observational VLBI jet features from MOJAVE to parameters expected for a VHE-emitting blob accelerated near the jet base. The VHE emission appears to be dominated by the inverse-Compton effect of the blob relativistic electrons interacting with the jet synchrotron radiation. In this scenario, Ap Lib appears as an intermediate source between BL Lac objects and flat-spectrum radio quasars. Ap Lib could be a bright representative of a specific class of blazars, in which the parsec-scale jet luminosity is no more negligible compared to the blob and contributes to the high-energy emission through inverse-Compton processes.

  20. Thrombin induces endothelial arginase through AP-1 activation.

    PubMed

    Zhu, Weifei; Chandrasekharan, Unni M; Bandyopadhyay, Smarajit; Morris, Sidney M; DiCorleto, Paul E; Kashyap, Vikram S

    2010-04-01

    Arterial thrombosis is a common disease leading to severe ischemia beyond the obstructing thrombus. Additionally, endothelial dysfunction at the site of thrombosis can be rescued by l-arginine supplementation or arginase blockade in several animal models. Exposure of rat aortic endothelial cells (RAECs) to thrombin upregulates arginase I mRNA and protein levels. In this study, we further investigated the molecular mechanism of thrombin-induced arginase changes in endothelial cells. Thrombin strikingly increased arginase I promoter and enzyme activity in primary cultured RAECs. Using different deletion and point mutations of the promoter, we demonstrated that the activating protein-1 (AP-1) consensus site located at -3,157 bp in the arginase I promoter was a thrombin-responsive element. Electrophoretic mobility shift assay and chromatin immunoprecipitation assay further confirmed that upon thrombin stimulation, c-Jun and activating transcription factor-2 (ATF-2) bound to the AP-1 site, which initiated the transactivation. Moreover, loss-of-function studies using small interfering RNA confirmed that recruitment of these two transcription factors to the AP-1 site was required for thrombin-induced arginase upregulation. In the course of defining the signaling pathway leading to the activation of AP-1 by thrombin, we found thrombin-induced phosphorylation of stress-activated protein kinase/c-Jun-NH(2)-terminal kinase (SAPK/JNK or JNK1/2/3) and p38 mitogen-activated protein kinase, which were followed by the phosphorylation of both c-Jun and ATF-2. These findings reveal the basis for thrombin induction of endothelial arginase I and indicate that arginase inhibition may be an attractive therapeutic alternative in the setting of arterial thrombosis and its associated endothelial dysfunction. PMID:20032511

  1. Studies on Nonaluminized High Burning Rate AP-Composite Propellants

    Microsoft Academic Search

    G. M. GORE; A. N. NAZARE; C. N. DIVEKAR; S. K. HAIT; S. N. ASTHANA

    2004-01-01

    This paper discusses the effect of replacement of hydroxyl terminated poly butadiene (HTPB) by butacene on the burning rates of a nonaluminized ammonium perchlorate (AP)based composite propellant. A remarkable burning rate enhancement (60100%) was observed on replacement of HTPB by butacene to the extent of 25%. Replacement of 5075% HTPB by butacene led to further increase in burning rate by

  2. Infrared imaging of AP\\/HTPB laminate propellant flames

    Microsoft Academic Search

    R. P. Fitzgerald; M. Q. Brewster

    2008-01-01

    The combustion of ammonium perchlorate (AP), hydroxyl-terminated polybutadiene (HTPB) two-dimensional laminate propellants is investigated using simultaneous infrared (IR) and ultraviolet (UV) emission imaging at 150 atm. The IR (33003900 nm) measurements sense flame presence nominally via HCl rovibrational excitation and the UV (310 nm) measurements via OH electronic excitation, although continuum emission is also present. The following findings are made.

  3. Diffusion and Settling in Ap/Bp Stars

    SciTech Connect

    Turcotte, S

    2003-04-09

    Ap/Bp stars are magnetic chemically peculiar early A and late B type stars of the main sequence. They exhibit peculiar surface abundance anomalies that are thought to be the result of gravitational settling and radiative levitation. The physics of diffusion in these stars are reviewed briefly and some model predictions are discussed. While models reproduce some observations reasonably well, more work is needed before the behavior of diffusing elements in a complex magnetic field is fully understood.

  4. Aps-based miniature sun sensor for earth observation nanosatellites

    Microsoft Academic Search

    Marcello Buonocore; Michele Grassi; Giancarlo Rufino

    2005-01-01

    This paper describes the research activity at the university of Naples concerning the design and prototype development of a low-cost APS-based miniature sun sensor for micro\\/nanosatellites applications. In the paper the sensor architecture is described, as well as the development of its prototype and of the facility for laboratory testing. Part of the project is also the development of a

  5. Research on Thin AP Architecture to Deploy Campus WLAN

    Microsoft Academic Search

    Kailiang Liang

    2011-01-01

    In this paper, the program uses the wireless AP to deploy campus wlan, in order to achieve a wide network coverage and security, high-speed data transmission. To meet the future needs of the campus network, we use the 802.11n standard, and adopt a new technique in management: a hardware device by carrying two or more ssid, to achieve efficient management

  6. Architecture of the APS real-time orbit feedback system.

    SciTech Connect

    Carwardine, J. A.; Lenkszus, F. R.

    1997-11-21

    The APS Real-Time Orbit Feedback System is designed to stabilize the orbit of the stored positron beam against low-frequency sources such as mechanical vibration and power supply ripple. A distributed array of digital signal processors is used to measure the orbit and compute corrections at a 1kHz rate. The system also provides extensive beam diagnostic tools. This paper describes the architectural aspects of the system and describes how the orbit correction algorithms are implemented.

  7. Normal Optical Flow measurement on a CMOS APS imager

    Microsoft Academic Search

    Swati Mehta; Ralph Etienne-cummings

    2004-01-01

    Results from a 2-D dense Normal Optical Flow measurement chip implemented in 0.5 ?m CMOS process are presented. The chip has a 9252 array of APS pixels, occupies an area of 4.5 mm2 and consumes 2.6 mW power. To illustrate the operation of the chip, we present the results of individual blocks and then the whole structure. We also demonstrate

  8. Wide intrascene dynamic range CMOS APS using dual sampling

    Microsoft Academic Search

    Orly Yadid-Pecht; Eric R. Fossum

    1997-01-01

    A CMOS active pixel sensor (APS) that achieves wide intrascene dynamic range using dual sampling is reported. A 6464 element prototype sensor with dual output architecture was fabricated using a 1.2 ?m n-well CMOS process with 20.4 ?m pitch photodiode-type active pixels. The sensor achieves an intrascene dynamic range of 109 dB without nonlinear companding

  9. Study of CMOS APS Responsivity Enhancement: Ring-Shaped Photodiode

    Microsoft Academic Search

    Tatiana Danov; Igor Shcherback; Orly Yadid-Pecht

    2005-01-01

    In this work the possibilities of CMOS APS spectral response improvement are discussed. Thorough submicron scanning results obtained from various ring-shaped pixel photodiodes with different inner radius, implemented in a standard CMOS 0.35m technology, are compared with numerical computer simulations. The functional dependence of the pixel response on the ring opening size was discovered and formulated for various wavelengths illumination.

  10. Development of large and fast cmos aps cameras at latt

    Microsoft Academic Search

    F. Beigbeder; E. Bourrec; M. Dupieux; G. Delaigue; S. Rondi; M. Rieutord; N. Meunier; T. Roudier

    2009-01-01

    Since 2004, at the Laboratoire d'Astrophysique de Toulouse Tarbes (LATT), we work with CMOS APS detectors, firstly to develop a large-field,high-resolution camera for the observation of the solar supergranulation, secondly to develop a fast camera for an adaptive optics test bench. In these two projects, we use detectors from FillFactory, now continued by Cypress Semiconductor Corporation: IBIS4-14000, IBIS-16000, LUPA-4000, 14

  11. Study of CMOS APS responsivity enhancement: ring-shaped photodiode

    Microsoft Academic Search

    Tatiana Danov; Igor Shcherback; Orly Yadid-Pecht

    2005-01-01

    In this brief, the possibilities of complementary metal-oxide-semiconductor (CMOS) active pixel sensor (APS) spectral response improvement are discussed. Thorough submicrometer scanning results obtained from various ring-shaped pixel photodiodes with different inner radius, implemented in a standard CMOS 0.35-?m technology, are compared with numerical computer simulations and verified analytically. The functional dependence of the pixel response on the ring opening size

  12. Photoresponse Analysis and Pixel Shape Optimization for CMOS APS

    Microsoft Academic Search

    Igor Shcherback; Orly Yadid-Pecht

    A semi-analytical model has been developed for the estimation of the photoresponse of a photodiode-based CMOS active pixel\\u000a sensor (APS). This model, based on a thorough analysis of experimental data, incorporates the effects of substrate diffusion\\u000a as well as geometrical shape and size of the photodiode active area. It describes the dependence of pixel response on integration\\u000a photocarriers and on

  13. Essay: computers in the APS editorial office: the early years.

    PubMed

    Adams, Peter

    2009-03-13

    APS journals in the late 1960s began to move from hot-metal print shops to tailor-made typewriters, next to special keyboards and a small computer, then to completely photocomposed journal pages. At the same time, internal editorial operations were being converted from paper handling and data records to completely electronic procedures. By 1990, it became feasible for authors to submit manuscripts to the journal electronically. PMID:19392091

  14. Essay: Computers in the APS Editorial Office: The Early Years

    NASA Astrophysics Data System (ADS)

    Adams, Peter

    2009-03-01

    APS journals in the late 1960s began to move from hot-metal print shops to tailor-made typewriters, next to special keyboards and a small computer, then to completely photocomposed journal pages. At the same time, internal editorial operations were being converted from paper handling and data records to completely electronic procedures. By 1990, it became feasible for authors to submit manuscripts to the journal electronically.

  15. Packaging design criteria, transfer and disposal of 102-AP mixer pump

    SciTech Connect

    Carlstrom, R.F.

    1994-11-23

    A mixer pump installed in storage tank 241-AP-102 (102-AP) has failed. This pump is referred to as the 102-AP mixer pump (APMP). The APMP will be removed from 102-AP 1 and a new pump will be installed. The main purpose of the Packaging Design Criteria (PDC) is to establish criteria necessary to design and fabricate a shipping container for the transfer and storage of the APMP from 102-AP. The PDC will be used as a guide to develop a Safety Evaluation for Packaging (SEP).

  16. AP Physics 1 & 2; Some Things Old and Some Things New

    NASA Astrophysics Data System (ADS)

    Morse, Robert

    2015-04-01

    In fall September 2014, AP Physics 1 and AP Physics 2 replaced the AP Physics B curriculum, with the first exams in the new courses coming up in May 2015. In this talk I will give an overview of the history and rationale for the changes, describe the process of developing the new Curriculum Framework, discuss changes in emphasis compared to AP Physics B, including the emphasis on laboratory work. Finally, I will give examples of the difference in the style of the questions to be used in the new AP exams.

  17. What do we know about the cardiac valve lesion in the antiphospholipid syndrome (APS)?

    PubMed

    Amigo, M-C

    2014-10-01

    Heart valve disease (HVD) is the most common cardiac manifestation in the antiphospholipid syndrome (APS). Valve lesions should be described according to the established definition. HVD is progressive despite anticoagulant/antiplatelet treatments. Around 4-6% of patients with HVD in APS will require valve replacement surgery, which is considered a very high risk procedure in APS. Unfortunately, no recommendations regarding medical treatment of antiphospholipid antibodies-associated HVD can be made at this moment. There are evidence-based data and strong pathophysiologic rationale for considering HVD as a manifestation of APS. Thus, HVD should be included as a criterion of definite APS. PMID:25228720

  18. Apollo 11 preflight press conference

    NASA Technical Reports Server (NTRS)

    1969-01-01

    The three prime crewmen of the Apollo 11 lunar landing mission participate in a pre-flight press conference in the bldg 1 auditorium on July 5, 1969. Left to right, are Astronauts Neil A. Armstrong, commander; Edwin E. Aldrin Jr., lunar module pilot; and Michael Collins, command module pilot. The box-like enclosure surrounding the three astronauts was part of elaborate precautions in effect to reduce the possibility of exposing the crewmen to infectious disease in the preflight period.

  19. Commerical Laundry, Drycleaning and Pressing Machine Manufacturing: 1997 Economic Census Manufacturing Industry Series

    NSDL National Science Digital Library

    1999-01-01

    The US Department of Commerce Census Bureau has released the few in a series of several hundred reports on individual industries in the manufacturing sector from the 1997 Economic Census. The 1997 Economic Census series on the Commercial Laundry, Drycleaning, and Pressing Machine Manufacturing does not include state comparisons but reports on total capital expenditures in Illinois as well as the US as a whole.

  20. Slurry-pressing consolidation of silicon nitride

    NASA Technical Reports Server (NTRS)

    Sanders, William A.; Kiser, James D.; Freedman, Marc R.

    1988-01-01

    A baseline slurry-pressing method for a silicon nitride material is developed. The Si3N4 composition contained 5.8 wt percent SiO2 and 6.4 wt percent Y2O3. Slurry-pressing variables included volume percent solids, application of ultrasonic energy, and pH. Twenty vol percent slurry-pressed material was approximately 11 percent stronger than both 30 vol percent slurry-pressed and dry-pressed materials. The Student's t-test showed the difference to be significant at the 99 percent confidence level. Twenty volume percent (300 h) slurry-pressed test bars exhibited strengths as high as 980 MPa. Large, columnar beta-Si3N4 grains caused failure in the highest strength specimens. The improved strength correlated with better structural uniformity as determined by radiography, optical microscopy, and image analysis.

  1. Work plan, AP-102 mixer pump removal and pump replacement

    SciTech Connect

    Jimenez, R.F.

    1994-09-01

    The objective of this work plan is to plan the steps and estimate the costs required to remove the failed AP-102 mixer pump, and to plan and estimate the cost of the necessary design and specification work required to order a new, but modified, mixer pump including the pump and pump pit energy absorbing design. The main hardware required for the removal of the mixer is as follows: a flexible receiver and blast shield; a metal container for the pulled mixer pump; and a trailer and strongback to haul and manipulate the container. Additionally: a gamma scanning device will be needed to detect the radioactivity emanating from the mixer as it is pulled from the tank; a water spray system will be required to remove tank waste from the surface of the mixer as it is pulled from the AP-102 tank; and a lifting yoke to lift the mixer from the pump pit (the SY-101 Mixer Lifting Yoke will be used). A ``green house`` will have to be erected over the AP-102 pump pit and an experienced Hoisting and Rigging crew must be assembled and trained in mixer pump removal methods before the actual removal is undertaken.

  2. Margin Assessment of AP1000 Loss of Flow Transient

    SciTech Connect

    Carlin, Edward L.; Hilton, Peter A.; Yixing Sung [Westinghouse Electric Company, LLC (United States)

    2006-07-01

    The Reactor Coolant System (RCS) of the AP1000 plant consists of two circulating loops. Each loop contains two canned motor Reactor Coolant (RC) pumps that have a rotating inertia to provide RCS flow coast-down if power to the pumps is lost. Westinghouse analysis of the complete loss of flow (CLOF) accident in support of the AP1000 design certification was based on the USNRC-approved traditional methodology applied to operating plants. The RCS response during the transient was predicted using the LOFTRAN code based on a reactivity insertion curve highly skewed to the bottom of the reactor core, but the calculation of Departure from Nucleate Boiling Ratio (DNBR) was performed assuming a top-skewed axial power profile. A more realistic margin assessment can be made by using an improved method similar to Westinghouse RAVE methodology recently approved by the USNRC. The improved method uses the three-dimensional kinetic nodal code SPNOVA coupled with the reactor core thermal-hydraulic code VIPRE-W for predicting the reactor core response during the CLOF transient. The improved method significantly improves margin predictions by generating core power distributions consistent with the trip reactivity changes for the DNBR calculation. The margin assessment showed that the improved method resulted in a 19% DNBR increase as compared to the traditional method for the AP1000 CLOF transient. (authors)

  3. Long-term stability of the APS storage ring

    SciTech Connect

    Friedsam, H.; Penicka, M.; Error, J.

    2000-03-16

    The Advanced Photon Source (APS), a third-generation synchrotron light source, was commissioned in 1995 at Argonne National Laboratory and has been fully operational for beamline users since 1997. The APS storage ring can accommodate up to 68 user beamlines; about 70% of the available beamlines are currently in use by various collaborative access teams (CATs). The 7-GeV synchrotron light source produces light in the soft to hard x-ray range that is used for research in such areas as x-ray instrumentation; material, chemical and atomic sciences; biology; and geo/soil/environmental sciences. For the successful operation of an x-ray light source such as the Advanced Photon Source, the long-term stability of the concrete floor supporting the beam components and user beamlines is crucial. Settlements impact the orbit and location of the x-ray source points as well as the position of the x-ray beamlines. This paper compares the results of two successive resurveys of the APS accelerator components performed in 1995 and 1998.

  4. Long-term stability of the APS storage ring

    SciTech Connect

    Friedsam, H.; Penicka, M.; Error, J.

    1999-10-26

    The Advanced Photon Source (APS), a third-generation synchrotrons light source, was commissioned in 1995 at Argonne ''National Laboratory and has been fully-operational for beamline users since 1997. The APS storage ring can accommodate up to 68 user beamlines; about 70% of the available beamlines are currently in use by various collaborative access teams (CATS). The 7-GeV synchrotrons light source produces light in the soft to hard x-ray range that is used for research in such areas as x-ray instrumentation; material, chemical and atomic sciences; biology; and geo/soil/ environmental sciences. For the successful operation of an x-ray light source such as the Advanced Photon Source, the long-term stability of the concrete floor supporting the beam components and user beamlines is crucial. Settlements impact the orbit and location of the x-ray source points as well as the position of the x-ray beamlines. This paper compares the results of two successive resurveys of the APS accelerator components performed in 1995 and 1998.

  5. Radial Electromagnetic Press for IGNITOR

    NASA Astrophysics Data System (ADS)

    Cucchiaro, A.; Anzidei, L.; Capriccioli, A.; Celentano, G.; Crescenzi, C.; Gasparotto, M.; Guerrieri, A.; Pizzuto, A.; Palmieri, A.; Rita, C.; Roccella, M.; Coppi, B.

    1998-11-01

    The structural performance of the IGNITOR machine relies upon a combination of both bucking between Toroidal Field Coils (TFCs), Central Solenoid (CS) and the Central Post (CP), and wedging in a well-defined area of the TFCs and of the magnet mechanical structure (called C-Clamps). This requires a pre-loading system to enhance the load bearing capability. Several solutions have been assessed and compared with each other within the operational scenarios and eventually a radial electromagnetic press has been selected as reference(Pizzuto A. et al., ENEA Report IGN/MAC/001/96). The loading system is made up by active coils and passive restraining rings. The radial active press consists of two pairs of coils (200x200mm each), symmetrically located relative to the machine equatorial plane and seating onto the passive rings. The permanent pre--load of the rings is applied through a wedging system with a load of about 120 MN. A radial electromagnetic press has the purpose of modulating the axial pressure on the TFC inner legs during the pulse. Design aspects including stress analysis, manufacturing, assembly and operational scenarios of the selected solution are presented in this paper.

  6. The Ignitor Radial Press System

    NASA Astrophysics Data System (ADS)

    Capriccioli, A.; Celentano, G.; Cucchiaro, A.; Gasparotto, M.; Rita, C.; Roccella, M.; Bianchi, A.

    1999-11-01

    A radial press system is employed to resist the high electromagnetic forces in the Ignitor machine. A permanent pre-load of about 190 MN is applied by retaining rings, while an active press modulates the axial pressure on the Toroidal Field Coils inner legs during the pulse current flat-top. Spurious effects at the time of the plasma formation are avoided. An optimal configuration has been deviced, leading to a series of important improvements. Using a radial rather than an axial press facilitates construction, installation, and removal of the central solenoids and central post. Furthermore, the central post can now take up the repulsive forces between the coils, allowing a greater freedom in programming the currents, and hence controlling the plasma shape. A better match can be obtained between the plasma boundary and the first wall, thus reducing the danger of localized heat loads, and the possibility of creating an X-point configuration is introduced. The improved mechanical flexibility of the machine has been achieved because of the reduced loads necessary on the passive bracing rings, while maintaining the wedging of the TF inner legs for both cold and warm machine, and during the pulse.

  7. The Drosophila melanogaster Mutants apblot and apXasta Affect an Essential apterous Wing Enhancer

    PubMed Central

    Bieli, Dimitri; Kanca, Oguz; Gohl, Daryl; Denes, Alexandru; Schedl, Paul; Affolter, Markus; Mller, Martin

    2015-01-01

    The selector gene apterous (ap) plays a key role during the development of the Drosophila melanogaster wing because it governs the establishment of the dorsal-ventral (D-V) compartment boundary. The D-V compartment boundary is known to serve as an important signaling center that is essential for the growth of the wing. The role of Ap and its downstream effectors have been studied extensively. However, very little is known about the transcriptional regulation of ap during wing disc development. In this study, we present a first characterization of an essential wing-specific ap enhancer. First, we defined an 874-bp fragment about 10 kb upstream of the ap transcription start that faithfully recapitulates the expression pattern of ap in the wing imaginal disc. Analysis of deletions in the ap locus covering this element demonstrated that it is essential for proper regulation of ap and formation of the wing. Moreover, we showed that the mutations apblot and apXasta directly affect the integrity of this enhancer, leading to characteristic wing phenotypes. Furthermore, we engineered an in situ rescue system at the endogenous ap gene locus, allowing us to investigate the role of enhancer fragments in their native environment. Using this system, we were able to demonstrate that the essential wing enhancer alone is not sufficient for normal wing development. The in situ rescue system will allow us to characterize the ap regulatory sequences in great detail at the endogenous locus. PMID:25840432

  8. CHICAGO JOURNALS Founded in 1891, the University of Chicago Press is the largest American university press.

    E-print Network

    Mateo, Jill M.

    CHICAGO JOURNALS :: #12;Founded in 1891, the University of Chicago Press is the largest American university press. The Journals Division has a rich history of presenting the work of top international to the latest issues of more than 200 high-quality journals from an esteemed group of university presses

  9. Freedom House: Press Freedom Survey 2000

    NSDL National Science Digital Library

    Published by Freedom House, a non-partisan advocacy organization for democracy and human rights worldwide founded by Eleanor Roosevelt, Wendell Willkie, and others, the 2000 edition of the Press Freedom Survey offers a "country-by-country worldwide assessment of press freedom." This year's study, which examines freedom of the press in 186 countries, pays special attention to government restrictions on Internet access. It finds that "nearly two-thirds of countries, accounting for 80 percent of the world's population, restrict press freedom." Users can download the full text of the 36-page report in .pdf format or view the country reports, methodology, and tables and charts in HTML format.

  10. NF-?B/AP-1-Targeted Inhibition of Macrophage-Mediated Inflammatory Responses by Depigmenting Compound AP736 Derived from Natural 1,3-Diphenylpropane Skeleton

    PubMed Central

    Ha, Van Thai; Beak, Heung Soo; Kim, Eunji; Baek, Kwang-Soo; Hossen, Muhammad Jahangir; Yang, Woo Seok; Kim, Yong; Joo, Yung Hyup; Lee, Chang Seok; Choi, Joonho; Shin, Hong-Ju; Hong, Sungyoul; Shin, Song Seok

    2014-01-01

    AP736 was identified as an antimelanogenic drug that can be used for the prevention of melasma, freckles, and dark spots in skin by acting as a suppressor of melanin synthesis and tyrosinase expression. Since macrophage-mediated inflammatory responses are critical for skin health, here we investigated the potential anti-inflammatory activity of AP736. The effects of AP736 on various inflammatory events such as nitric oxide (NO)/prostaglandin (PG) E2 production, inflammatory gene expression, phagocytic uptake, and morphological changes were examined in RAW264.7 cells. AP736 was found to strongly inhibit the production of both NO and PGE2 in lipopolysaccharide- (LPS-) treated RAW264.7 cells. In addition, AP736 strongly inhibited both LPS-induced morphological changes and FITC-dextran-induced phagocytic uptake. Furthermore, AP736 also downregulated the expression of multiple inflammatory genes, such as inducible NO synthase (iNOS), cyclooxygenase- (COX-) 2, and interleukin- (IL-) 1? in LPS-treated RAW264.7 cells. Transcription factor analysis, including upstream signalling events, revealed that both NF-?B and AP-1 were targeted by AP736 via inhibition of the IKK/I?B? and IRAK1/TAK1 pathways. Therefore, our results strongly suggest that AP736 is a potential anti-inflammatory drug due to its suppression of NF-?B-IKK/I?B? and AP-1-IRAK1/TAK1 signalling, which may make AP736 useful for the treatment of macrophage-mediated skin inflammation. PMID:25386046

  11. The Heptameric SmAP1 and SmAP2 Proteins of the Crenarchaeon Sulfolobus Solfataricus Bind to Common and Distinct RNA Targets.

    PubMed

    Mrtens, Birgit; Bezerra, Gustavo Arruda; Kreuter, Mathias Josef; Grishkovskaya, Irina; Manica, Andrea; Arkhipova, Valentina; Djinovic-Carugo, Kristina; Blsi, Udo

    2015-01-01

    Sm and Sm-like proteins represent an evolutionarily conserved family with key roles in RNA metabolism. Sm-based regulation is diverse and can range in scope from eukaryotic mRNA splicing to bacterial quorum sensing, with at least one step in these processes being mediated by an RNA-associated molecular assembly built on Sm proteins. Despite the availability of several 3D-structures of Sm-like archaeal proteins (SmAPs), their function has remained elusive. The aim of this study was to shed light on the function of SmAP1 and SmAP2 of the crenarchaeon Sulfolobus solfataricus (Sso). Using co-purification followed by RNASeq different classes of non-coding RNAs and mRNAs were identified that co-purified either with both paralogues or solely with Sso-SmAP1 or Sso-SmAP2. The large number of associated intron-containing tRNAs and tRNA/rRNA modifying RNAs may suggest a role of the two Sso-SmAPs in tRNA/rRNA processing. Moreover, the 3D structure of Sso-SmAP2 was elucidated. Like Sso-SmAP1, Sso-SmAP2 forms homoheptamers. The binding of both proteins to distinct RNA substrates is discussed in terms of surface conservation, structural differences in the RNA binding sites and differences in the electrostatic surface potential of the two Sso-SmAP proteins. Taken together, this study may hint to common and different functions of both Sso-SmAPs in Sso RNA metabolism. PMID:25905548

  12. The Heptameric SmAP1 and SmAP2 Proteins of the Crenarchaeon Sulfolobus Solfataricus Bind to Common and Distinct RNA Targets

    PubMed Central

    Mrtens, Birgit; Bezerra, Gustavo Arruda; Kreuter, Mathias Josef; Grishkovskaya, Irina; Manica, Andrea; Arkhipova, Valentina; Djinovic-Carugo, Kristina; Blsi, Udo

    2015-01-01

    Sm and Sm-like proteins represent an evolutionarily conserved family with key roles in RNA metabolism. Sm-based regulation is diverse and can range in scope from eukaryotic mRNA splicing to bacterial quorum sensing, with at least one step in these processes being mediated by an RNA-associated molecular assembly built on Sm proteins. Despite the availability of several 3D-structures of Sm-like archaeal proteins (SmAPs), their function has remained elusive. The aim of this study was to shed light on the function of SmAP1 and SmAP2 of the crenarchaeon Sulfolobus solfataricus (Sso). Using co-purification followed by RNASeq different classes of non-coding RNAs and mRNAs were identified that co-purified either with both paralogues or solely with Sso-SmAP1 or Sso-SmAP2. The large number of associated intron-containing tRNAs and tRNA/rRNA modifying RNAs may suggest a role of the two Sso-SmAPs in tRNA/rRNA processing. Moreover, the 3D structure of Sso-SmAP2 was elucidated. Like Sso-SmAP1, Sso-SmAP2 forms homoheptamers. The binding of both proteins to distinct RNA substrates is discussed in terms of surface conservation, structural differences in the RNA binding sites and differences in the electrostatic surface potential of the two Sso-SmAP proteins. Taken together, this study may hint to common and different functions of both Sso-SmAPs in Sso RNA metabolism. PMID:25905548

  13. Syllabus Fall 2014 | APS 1019 Leadership in Project Management | Dr. Haig Baronikian 1 A) Title: APS1019 Leadership in Project Management

    E-print Network

    Prodi, Aleksandar

    Syllabus Fall 2014 | APS 1019 Leadership in Project Management | Dr. Haig Baronikian 1 A) Title: APS1019 Leadership in Project Management B) Description: Project management involves both leading people and managing resources to achieve the intended project outcomes and benefits. Leadership is often

  14. Draft Genome Sequences of Clinical Daptomycin-Nonsusceptible Methicillin-Resistant Staphylococcus aureus (MRSA) Strain APS211 and Its Daptomycin-Susceptible Progenitor APS210

    PubMed Central

    Cameron, David R.; Jiang, Jhih-Hang; Abbott, Iain J.; Spelman, Denis W.

    2015-01-01

    To assess the genetic factors contributing to daptomycin resistance in Staphylococcus aureus, the draft genome of a clinically derived daptomycin-nonsusceptible isolate APS211 was generated and compared to the draft sequence of its susceptible progenitor strain APS210. Four genetic differences were identified including a previously described mutation within the mprF gene. PMID:26067951

  15. Recognition of dileucine-based sorting signals from HIV1 Nef and LIMP-II by the AP1 -1 and AP3 -3 hemicomplexes

    Microsoft Academic Search

    Katy Janvier; Yukio Kato; Markus Boehm; Jeremy R. Rose; Jos A. Martina; Bong-Yoon Kim; Sundararajan Venkatesan; Juan S. Bonifacino

    2003-01-01

    he sorting of transmembrane proteins to endosomes and lysosomes is mediated by signals present in the cytosolic tails of the proteins. A subset of these signals conform to the (DE)XXXL(LI) consensus motif and mediate sorting via interactions with heterotetrameric adaptor pro- tein (AP) complexes. However, the identity of the AP sub- units that recognize these signals remains controversial. We have

  16. Implementing Strategies for Drying and Pressing Wood Without Emissions Controls

    SciTech Connect

    Sujit Banerjee; Terrance Conners

    2007-09-07

    Drying and pressing wood for the manufacture of lumber, particleboard, oriented strand board (OSB), veneer and medium density fiberboard (MDF) release volatile organic compounds (VOCs) into the atmosphere. These emissions require control equipment that are capital-intensive and consume significant quantities of natural gas and electricity. The objective of our work was to understand the mechanisms through which volatile organic compounds are generated and released and to develop simple control strategies. Of the several strategies developed, two have been implemented for OSB manufacture over the course of this study. First, it was found that increasing final wood moisture by about 2-4 percentage points reduced the dryer emissions of hazardous air pollutants by over 70%. As wood dries, the escaping water evaporatively cools the wood. This cooling tapers off wood when the wood is nearly dry and the wood temperature rises. Thermal breakdown of the wood tissue occurs and VOCs are released. Raising the final wood moisture by only a few percentage points minimizes the temperature rise and reduces emissions. Evaporative cooling also impacts has implications for VOC release from wood fines. Flaking wood for OSB manufacture inevitable generates fines. Fines dry out rapidly because of their high surface area and evaporative cooling is lost more rapidly than for flakes. As a result, fines emit a disproportionate quantity of VOCs. Fines can be reduced in two ways: through screening of the green furnish and through reducing their generation during flaking. The second approach is preferable because it also increased wood yield. A procedure to do this by matching the sharpness angle of the flaker knife to the ambient temperature was also developed. Other findings of practical interests are as follows: Dielectric heating of wood under low-headspace conditions removes terpenes and other extractives from softwood; The monoterpene content in trees depend upon temperature and seasonal effects; Method 25A emissions from lumber drying can be modeled from a knowledge of the airflow through the kiln; A heat transfer model shows that VOCs released during hot-pressing mainly originate from the surface of the board; and Boiler ash can be used to adsorb formaldehyde from air streams.

  17. Evaluation of the new radiation belt AE9/AP9/SPM model for a cislunar mission

    NASA Astrophysics Data System (ADS)

    Badavi, Francis F.; Walker, Steven A.; Santos Koos, Lindsey M.

    2014-09-01

    Space mission planners continue to experience challenges associated with human space flight. Concerned with the omnipresence of harmful ionizing radiation in space, at the mission design stage, mission planners must evaluate the amount of exposure the crew of a spacecraft is subjected to during the transit trajectory from low Earth orbit (LEO) to geosynchronous orbit (GEO) and beyond (free space). The Earth's geomagnetic field is located within the domain of LEO-GEO and, depending on latitude, extends out some 40,000-60,000 km. This field contains the Van Allen trapped electrons, protons, and low-energy plasmas, such as the nuclei of hydrogen, helium, oxygen, and to a lesser degree other atoms. In addition, there exist the geomagnetically attenuated energetic galactic cosmic rays (GCR). These particles are potentially harmful to improperly shielded crew members and onboard subsystems. Mitigation strategies to limit the exposure due to free space GCR and sporadic solar energetic particles (SEP) such as flare and coronal mass ejection (CME) must also be exercised beyond the trapped field. Presented in this work is the exposure analysis for a multi-vehicle mission planned for the epoch of February 2020 from LEO to the Earth-moon Lagrange-point two (L2), located approximately 63,000 km beyond the orbit of the Earth-moon binary system. Space operation at L2 provides a gravitationally stable orbit for a vehicle and partially eliminates the need for periodic thrust-vectoring to maintain orbital stability. In the cislunar (Earth-moon) space of L2, the mission trajectory and timeline in this work call for a cargo vehicle to rendezvous with a crew vehicle. This is followed by 15 days of space activities at L2 while the cargo and crew vehicles are docked after which the crew returns to Earth. The mission epoch of 2020 is specifically chosen as it is anticipated that the next solar minimum (i.e. end of cycle 24) in the Sun's approximate 11 years cycle will take place around this time. From a mission planning point of view, this date is ideal as the predictable GCR exposure will be at a maximum, while the sporadic SEP will be at a minimum. In addition, it is anticipated that by 2020 a vehicle capable of launching a crew of four will be operationally ready. During the LEO-GEO transit, the crew and cargo vehicles will encounter exposure from trapped particles and attenuated GCR, followed by free space exposure due to GCR and SEP during solar active times. Within the trapped field, a challenge arises from properly calculating the amount of exposure acquired. Within this field, in the absence of SEP (i.e. solar quiet times), the vehicles will have to transit through an inner proton belt, an inner and outer electron belts, and an attenuated GCR field. There exist a number of models to define the intensities of the trapped particles during the quiet and active SEP. Among the more established trapped models are the historic and popular electron/proton AE8/AP8 model dating back to the 1980s, the historic and less popular electron/proton CRRES model dating back to 1990s, and the recently released electron/proton/space plasma AE9/AP9/SPM model. The AE9/AP9/SPM model is a major improvement over the older AE8/AP8 and CRRES models. This model is derived from numerous measurements acquired over four solar cycles dating back to the 1970s, roughly representing 40 years of data collection. In contrast, the older AE8/AP8 and CRRES models were limited to only a few months of measurements taken during the prior solar minima and maxima. In this work, within the trapped field, along the design trajectory of the crew vehicle, the AE9/AP9/SPM model is evaluated against the older AE8/AP8 model during solar quiet times. The analysis is then extended to the GCR dominated en-route, cislunar L2 space and return trajectories in order to provide cumulative exposure estimates to the crew vehicle for the duration of the entire mission.

  18. The relationship between plateau burning behavior and ammonium perchlorate particle size in HTPB-AP composite propellants

    Microsoft Academic Search

    C. W. Fong; R. F. Smith

    1987-01-01

    The burning rates of series of bi- and trimodal AP-HTPB propellants have been incorporated into an empirical statistical model which describes a hypothetical pentamodal polydisperse AP pseudopropellant. This pseudopropellant is the linear summation of five unimodal polydisperse AP pseudopropellants. The five AP particle size distributions cover the range from 400 to 20 ..mu..m weight median diameter. The experimental propellants have

  19. AP180 Couples Protein Retrieval to Clathrin-Mediated Endocytosis of Synaptic Vesicles

    PubMed Central

    Vanlandingham, Phillip A; Barmchi, Mojgan Padash; Royer, Suzanne; Green, Rebekah; Bao, Hong; Reist, Noreen; Zhang, Bing

    2014-01-01

    How clathrin-mediated endocytosis (CME) retrieves vesicle proteins into newly formed synaptic vesicles (SVs) remains a major puzzle. Besides its roles in stimulating clathrin-coated vesicle formation and regulating SV size, the clathrin assembly protein AP180 has been identified as a key player in retrieving SV proteins. The mechanisms by which AP180 recruits SV proteins are not fully understood. Here, we show that following acute inactivation of AP180 in Drosophila, SV recycling is severely impaired at the larval neuromuscular synapse based on analyses of FM 1-43 uptake and synaptic ultrastructure. More dramatically, AP180 activity is important to maintain the integrity of SV protein complexes at the plasma membrane during endocytosis. These observations suggest that AP180 normally clusters SV proteins together during recycling. Consistent with this notion, SV protein composition and distribution are altered in AP180 mutant flies. Finally, AP180 co-immunoprecipitates with SV proteins, including the vesicular glutamate transporter and neuronal synaptobrevin. These results reveal a new mode by which AP180 couples protein retrieval to CME of SVs. AP180 is also genetically linked to Alzheimer's disease. Hence, the findings of this study may provide new mechanistic insight into the role of AP180 dysfunction in Alzheimer's disease. PMID:24456281

  20. Identification and Proteomic Analysis of Distinct UBE3A/E6AP Protein Complexes

    PubMed Central

    Martnez-Nol, Gustavo; Galligan, Jeffrey T.; Sowa, Mathew E.; Arndt, Verena; Overton, Thomas M.; Harper, J. Wade

    2012-01-01

    The E6AP ubiquitin ligase catalyzes the high-risk human papillomaviruses' E6-mediated ubiquitylation of p53, contributing to the neoplastic progression of cells infected by these viruses. Defects in the activity and the dosage of E6AP are linked to Angelman syndrome and to autism spectrum disorders, respectively, highlighting the need for precise control of the enzyme. With the exception of HERC2, which modulates the ubiquitin ligase activity of E6AP, little is known about the regulation or function of E6AP normally. Using a proteomic approach, we have identified and validated several new E6AP-interacting proteins, including HIF1AN, NEURL4, and mitogen-activated protein kinase 6 (MAPK6). E6AP exists as part of several different protein complexes, including the proteasome and an independent high-molecular-weight complex containing HERC2, NEURL4, and MAPK6. In examining the functional consequence of its interaction with the proteasome, we found that UBE3C (another proteasome-associated ubiquitin ligase), but not E6AP, contributes to proteasomal processivity in mammalian cells. We also found that E6 associates with the HERC2-containing high-molecular-weight complex through its binding to E6AP. These proteomic studies reveal a level of complexity for E6AP that has not been previously appreciated and identify a number of new cellular proteins through which E6AP may be regulated or functioning. PMID:22645313

  1. RAD51AP2, a novel vertebrate- and meiotic-specific protein, sharesa conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51

    SciTech Connect

    Kovalenko, Oleg V.; Wiese, Claudia; Schild, David

    2006-07-25

    Many interacting proteins regulate and/or assist the activities of RAD51, a recombinase which plays a critical role in both DNA repair and meiotic recombination. Yeast two-hybrid screening of a human testis cDNA library revealed a new protein, RAD51AP2 (RAD51 Associated Protein 2), that interacts strongly with RAD51. A full-length cDNA clone predicts a novel vertebrate specific protein of 1159 residues, and the RAD51AP2 transcript was observed only in meiotic tissue (i.e. adult testis and fetal ovary), suggesting a meiotic-specific function for RAD51AP2. In HEK293 cells the interaction of RAD51 with an ectopically-expressed recombinant large fragment of RAD51AP2 requires the C-terminal 57 residues of RAD51AP2. This RAD51-binding region shows 81% homology to the C-terminus of RAD51AP1/PIR51, an otherwise totally unrelated RAD51-binding partner that is ubiquitously expressed. Analyses using truncations and point mutations in both RAD51AP1 and RAD51AP2 demonstrate that these proteins use the same structural motif for RAD51 binding. RAD54 shares some homology with this RAD51-binding motif, but this homologous region plays only an accessory role to the adjacent main RAD51-interacting region, which has been narrowed here to 40 amino acids. A novel protein, RAD51AP2, has been discovered that interacts with RAD51 through a C-terminal motif also present in RAD51AP1.

  2. ApiAP2 transcription factor restricts development of the Toxoplasma tissue cyst

    PubMed Central

    Radke, Joshua B.; Lucas, Olivier; De Silva, Erandi K.; Ma, YanFen; Sullivan, William J.; Weiss, Louis M.; Llinas, Manuel; White, Michael W.

    2013-01-01

    Cellular differentiation leading to formation of the bradyzoite tissue cyst stage is the underlying cause of chronic toxoplasmosis. Consequently, mechanisms responsible for controlling development in the Toxoplasma intermediate life cycle have long been sought. Here, we identified 15 Toxoplasma mRNAs induced in early bradyzoite development that encode proteins with apicomplexan AP2 (ApiAP2) DNA binding domains. Of these 15 mRNAs, the AP2IX-9 mRNA demonstrated the largest expression increase during alkaline-induced differentiation. At the protein level, we found that AP2IX-9 was restricted to the early bradyzoite nucleus and is repressed in tachyzoites and in mature bradyzoites from 30-d infected animals. Conditional overexpression of AP2IX-9 significantly reduced tissue cyst formation and conferred alkaline pH-resistant growth, whereas disruption of the AP2IX-9 gene increased tissue cyst formation, indicating AP2IX-9 operates as a repressor of bradyzoite development. Consistent with a role as a repressor, AP2IX-9 specifically inhibited the expression of bradyzoite mRNAs, including the canonical bradyzoite marker, bradyzoite antigen 1 (BAG1). Using protein binding microarrays, we established the AP2 domain of AP2IX-9 binds a CAGTGT DNA sequence motif and is capable of binding cis-regulatory elements controlling the BAG1 and bradyzoite-specific nucleoside triphosphatase (B-NTPase) promoters. The effect of AP2IX-9 on BAG1 expression was direct because this factor inhibits expression of a firefly luciferase reporter under the control of the BAG1 promoter in vivo, and epitope-tagged AP2IX-9 can be immunoprecipitated with the BAG1 promoter in parasite chromatin. Altogether, these results indicate AP2IX-9 restricts Toxoplasma commitment to develop the mature bradyzoite tissue cyst. PMID:23572590

  3. Fracture toughness of hot-pressed beryllium

    NASA Technical Reports Server (NTRS)

    Lemon, D. D.; Brown, W. F., Jr.

    1985-01-01

    This paper presents the results of an investigation into the fracture toughness, sustained-load flaw growth, and fatigue-crack propagation resistance of S200E hot-pressed beryllium at room temperature. It also reviews the literature pertaining to the influence of various factors on the fracture toughness of hot-pressed beryllium determined using fatigue-cracked specimens.

  4. The Press and Journals in Communist China.

    ERIC Educational Resources Information Center

    Liu, Alan P. L.

    A general discussion is presented of the development of newspaper and journal enterprises in Communist China. The author begins by reviewing the political role that the Chinese press played in the Republican Revolution of 1911. Then the author traces the history of the Chinese Communist press in its two decades of insurgency. The post-1949

  5. Economics & Finance press.princeton.edu

    E-print Network

    Landweber, Laura

    Economics & Finance 2012 press.princeton.edu #12;TEXT Professors who wish to consider a book from & Research 18 Game Theory 22 Finance 23 Econometrics, Mathematical & Applied Economics 26 Political Economy page 25 see page 3 see page 12 see page 20 Contents #12;press.princeton.edu 1 forThcoming Finance

  6. Consumer Satisfaction with Durable-Press Shirts.

    E-print Network

    Stover, Mary Sue

    1972-01-01

    -.....-.------------------------ 6 Shirt Appearance .---..-.--~~----------------- 8 Shirt Preference by Consumers ---..-------------- 8 Commercially Laundered Shirts ---.----.--.------- 8 Results of Physical Tests ...................................... 8 A Permeability 8... Summary Little is known of consumer satisfaction with durable-press garments worn and laundered under typical circumstances. Because more than 90 percent of men's dre~s shirts are produced with a durable-press finish, they were selected...

  7. Critical discourse analysis of political press conferences

    Microsoft Academic Search

    Aditi Bhatia

    2006-01-01

    This study of political press conferences allows a closer look at diplomatic talk to communicate political differences in a positive way to smooth out socio-political and ideological discrepancies that often divide prominent political figures. Taking a critical discourse analysis (CDA) perspective, this article analyses textual data from press conferences involving the former Chinese President Jiang Zemin and the US President

  8. University of Calgary Press AFTER APPROPRIATION

    E-print Network

    Calgary, University of

    University of Calgary Press AFTER APPROPRIATION: EXPLORATIONS IN INTERCULTURAL PHILOSOPHY a third party indirectly via use or distribution of the work; distribute in or through a commercial body around open access used by Australian publisher, re.press, and thank them for giving us permission

  9. The Pedagogical Press: Problems and Trends.

    ERIC Educational Resources Information Center

    Soviet Education, 1990

    1990-01-01

    Presents a discussion by journalists, scientists, and writers on educational problems in the Soviet Union. Focuses on the the role of the pedagogical press in restructuring public education in light of perestroika. Calls for press involvement in defining and developing public education. Lists questions for consideration and invites responses. (NL)

  10. Taking Stock: North American Pollutant Releases and Transfers 1995

    NSDL National Science Digital Library

    1998-01-01

    This newly-online document from the Commission for Environmental Cooperation (CEC) describes "encouraging signs of a drop in pollution" from the major North American industries. The report, available in .pdf format, provides "a continental picture of pollutant release and transfer data (PRTD), based on information provided by the three governments from their domestic PRTD inventories." Users may download the following sections: Preface; Pollutant Releases and Transfers in North America; 1995 Canada and US Data Compared (Based on Matched Chemical/Industry Data Set); 1994 and 1995 Canada and US Data Compared (Based on Matched Chemical/Industry Data Set); Special Analyses; Border and Transborder Analyses; The Pulp and Paper Industry in Canada and the United States; Appendix A: A Comparison of Chemicals Listed under 1995 TRI, NPRI and RETC; and several press releases.

  11. Development of liquid-film tracking models for analysis of AP-600 passive containment cooling system

    SciTech Connect

    Sun, J.G.; Sha, W.T. [Argonne National Lab., IL (United States); Chen, Y.S. [Nuclear Regulatory Commission, Washington, DC (United States)

    1993-10-01

    The AP-600, an advanced pressurized water reactor, utilizes a passive containment cooling system (PCCS) to remove heat released inside the containment vessel following postulated design-base accidents (DBAS) such as a main-steam-line break or loss-of-coolant accident. The containment vessel consists of a vertical cylindrical shell and is capped at both top and bottom by a dome that is also a body of revolution with a meridian cross section in the shape of a semiellipse with a horizontal major axis. During a DBA, heat released to the interior of the steel containment vessel is removed by evaporation of a continuously flowing thin liquid film on the outside surface of the vessel, thus lowering the temperature of the steel vessel wall so that steam condenses on its inside surface. The external liquid film is formed by flooding water at top of the ellipsoidal dome. Evaporation of the falling liquid film is enhanced by buoyancy-driven flows of moist air in an annular space outside the steel containment vessel. To ensure PCCS performance, it is necessary to predict both the evaporating film on the outside surface of the vessel and the condensate film on its inside. To this end, two liquid-film tracking models for time-dependent flows (a simplified model and a comprehensive model) have been developed and implemented in the COMMIX code. COMMIX is a general-purpose, time-dependent, multidimensional computer code for thermal hydraulic analysis of single- or multicomponent engineering systems. It solves a system of conservation equations of continuities for up to six species, mixture momentum, and mixture energy, and a k-{epsilon} two-equation turbulent model. A unique feature of the COMMIX code is its porous-media formulation, which represents the first unified approach to thermal-hydraulic analysis. The tracking models discussed in this report compute the liquid-film thickness, its mean velocity, and its temperature on both sides of the steel containment vessel.

  12. Toxic Release Inventory (TRI)

    NSDL National Science Digital Library

    United States. Environmental Protection Agency.

    1996-01-01

    As part of the Emergency Planning and Community Right to Know Act, the US Environmental Protection Agency recently released data concerning toxic releases for 1996. The data for each state and federal facility are available in compressed (.exe) dBase format (.dbf). Information contained in each data file includes reporting facility, chemical names, aggregate release data, and total chemical transfers. The report is available as a series of Adobe Acrobat (.pdf) files.

  13. 24 APS STEP-UP Fellows Present Research at NIH

    NSDL National Science Digital Library

    APS Education Office (American Physiological Society Education Office)

    2012-10-01

    This article is on page 174-175 of The Physiologist, October 2012. The 24 APS NIDDK STEP-UP Fellows recently finished their eight-12-week laboratory research experience and traveled to Bethesda, MD to participate in the STEP-UP Research Symposium held at the DoubleTree Bethesda Hotel and at NIH. They were joined by the other 62 NIDDK STEP-UP fellows from the other four Coordinating Centers (Children?s Hospital, Los Angeles; Pennsylvania State Univ.; Univ. of Maryland,Baltimore County; and Virginia Commonwealth Univ.).

  14. Abort interlock diagnostic for protection of APS vacuum chamber

    SciTech Connect

    Decker, G.

    1993-06-01

    The Advanced Photon Source (APS) vacuum system has been designed to be passively safe from bending magnet radiation heating at positron beam currents up to 30 mA. Above this value, certain components may be damaged from vertical beam missteering, although work is proceeding to raise the safe current threshold. Because of this, a system for preventing the misalignment of high power density beams is required. This report details a system for protection from dipole radiation only. Work on a system for ID radiation is continuing.

  15. Operation of the APS photoinjector drive laser system.

    SciTech Connect

    Li, Y.; Accelerator Systems Division (APS)

    2008-08-04

    The APS photoinjector drive laser system has been in operation since 1999 and is achieving a performance level exceeding the requirement of stable operation of the LEUTL FEL system. One remarkable number is the UV energy stability of better than 2% rms, sometimes less than 1% rms. This report summarizes the operation experience of the laser system and the improvements made along the way. We also outline the route of upgrade of the system and some frontier laser research and development opportunities in ultrabright electron beam generation.

  16. Gonadotropin-releasing hormone in protostomes: insights from functional studies on Aplysia californica.

    PubMed

    Sun, Biao; Kavanaugh, Scott I; Tsai, Pei-San

    2012-05-01

    Several protostomian molecules that structurally resemble chordate gonadotropin-releasing hormone (GnRH) have been identified through cloning, biochemical purification or data mining. These molecules share considerable sequence and structural similarities with chordate GnRH, leading to the current belief that protostomian and chordate forms of GnRH share a common ancestor. However, the physiological significance of these protostomian GnRH-like molecules remains poorly understood. This knowledge gap hampers our understanding of how GnRH has evolved functionally over time. This review provides a summary of our recent functional characterization of a GnRH-like molecule (ap-GnRH) in a gastropod mollusk, Aplysia californica, and presents preliminary proof for a cognate ap-GnRH receptor (ap-GnRHR). Our data reveal that ap-GnRH is a general neural regulator capable of exerting diverse central and motor effects, but plays little or no role in reproductive activation. This notion is supported by the abundance of a putative ap-GnRHR transcript in the central nervous system and the foot. Comparing these results to the available functional data from a cephalopod mollusk, Octopus vulgaris, we surmise that protostomian GnRH-like molecules are likely to assume a wide range of physiological roles, and reproductive activation is not an evolutionarily conserved role of these molecules. Future functional studies using suitable protostomian models are required to identify functional changes in protostomian GnRH-like molecules that accompany major taxa-level transitions. PMID:22172342

  17. In-flight quality evaluation of attitude measurements from STECE APS-01 star tracker

    NASA Astrophysics Data System (ADS)

    Lai, Yuwang; Liu, Junhong; Ding, Yonghe; Gu, Defeng; Yi, Dongyun

    2014-09-01

    The STECE satellite is a small satellite mission of China for space technology experiment and climate exploration. To test the in-flight performance of the CMOS Active Pixel Sensor (APS) based star trackers, the APS-01 star tracker has been loaded on the STECE satellite. The APS-01 star tracker payload delivers 1 Hz real time telemetry attitude data during its in-orbit experiment mission. These attitude data have been analyzed and evaluated down to the specification requirements like random noise, systematic bias and low frequency error in this paper. The systematic bias of APS-01, including precession-nutation, aberration and relative installation error, has been calibrated. An approach is proposed to analyze the attitude low frequency errors of APS-01. The results of the evaluation can contribute to a better understanding as well as further refinements of the CMOS APS based star trackers.

  18. UW Madison Libraries: Parallel Press

    NSDL National Science Digital Library

    UW-Madison Libraries' Parallel Press combines book publishing traditions with new technology to provide print-on-demand books and a series of chapbooks (small, inexpensive books featuring the works of authors and poets with a Wisconsin connection). Print-on-demand books parallel the online editions created by the Libraries' digitizing initiatives. Currently, four titles, including David Hayman's A First-Draft Version of Finnegan's Wake (originally published in 1963) and The Book of Beasts (1954), by T.H. White, are available via Parallel Press print-on-demand service. The poetry chapbook series began in 1999 with the publication of four Wisconsin poets (Elizabeth Oness, Max Garland, Katharine Whitcomb, and Andrea Potos) and has continued with six chapbooks per year. A prose chapbook series began in 2002 with American Trilogy. This chapbook consists of historical reproductions of the American Declaration of Independence, Constitution, and Bill of Rights, with introductory material by UW Professor Stephen E. Lucas, and an afterword by John P. Kaminski, Director of the Center for the Study of the American Constitution -- published as part of a one year later, university-wide reflection, on the impact of the Sept. 11, 2001, terrorist attacks.

  19. Apurinic/apyrimidinic (AP) site recognition by the 5?-dRP/AP lyase in poly(ADP-ribose) polymerase-1 (PARP-1)

    PubMed Central

    Khodyreva, S. N.; Prasad, R.; Ilina, E. S.; Sukhanova, M. V.; Kutuzov, M. M.; Liu, Y.; Hou, E. W.; Wilson, S. H.; Lavrik, O. I.

    2010-01-01

    The capacity of human poly(ADP-ribose) polymerase-1 (PARP-1) to interact with intact apurinic/apyrimidinic (AP) sites in DNA has been demonstrated. In cell extracts, sodium borohydride reduction of the PARP-1/AP site DNA complex resulted in covalent cross-linking of PARP-1 to DNA; the identity of cross-linked PARP-1 was confirmed by mass spectrometry. Using purified human PARP-1, the specificity of PARP-1 binding to AP site-containing DNA was confirmed in competition binding experiments. PARP-1 was only weakly activated to conduct poly(ADP-ribose) synthesis upon binding to AP site-containing DNA, but was strongly activated for poly(ADP-ribose) synthesis upon strand incision by AP endonuclease 1 (APE1). By virtue of its binding to AP sites, PARP-1 could be poised for its role in base excision repair, pending DNA strand incision by APE1 or the 5?-dRP/AP lyase activity in PARP-1. PMID:21127267

  20. ED 50 AP Block Predictions for Phenyl Substituted and Unsubstituted n -Alkanols

    Microsoft Academic Search

    R. Hahin; A. Kondratiev

    2001-01-01

    . A series of n-alkanols and phenyl-substituted n-alkanols (?-alkanols) of increasing chain length and phenol were characterized for their ability to block action potentials\\u000a (APs) in frog sciatic nerves. APs were recorded using the single sucrose-gap method. The degree of AP attenuation when the nerve was exposed to different concentrations of an alcohol was used to construct dose-response curves.\\u000a The