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Last update: August 15, 2014.
1

Press Release Writing  

NSDL National Science Digital Library

As expected, Press Release Writing, from Accurate Online Solutions, offers a helpful tutorial on the art of press release writing. The advice is broken into several easily digestible sections, covering the main themes of the advertising vs. public relations debate, essentials of writing press releases, templates, formats, and samples. The site also offers comprehensive distribution lists for all media formats including electronic media, magazines, newspapers, wire services, and television stations. Interested users will want to subscribe to the free Press Release Writing enewsletter.

2

Issues in Ecology, Issue 14 Press Release  

NSDL National Science Digital Library

This November 2011 press release can be used as an accessible reading assignment to accompany and introduce a discussion of the ecological concepts included in issue #14 of ESA's Issues in Ecology series, "Using air pollution thresholds to protect and restore ecosystem health."

Lester, Liza

2012-03-07

3

Corporate governance and impression management in annual press releases  

Microsoft Academic Search

We study the association between corporate governance and impression management in annual results press releases (ARPRs). Press releases constitute a timely vehicle to communicate firm performance to third parties. However, oftentimes, managers provide self-serving disclosures that attempt to distort readers¿ perceptions of corporate achievements. Corporate governance mechanisms actively monitor managerial disclosures, improving firm transparency. Thus, we predict that strong governance

Beatriz García Osma; Encarna Guillamón Saorín

2009-01-01

4

Recurable Durable Press Fabric with Soil Release Properties.  

National Technical Information Service (NTIS)

The patent application relates to improved combinations of catalysts, crosslinking reagents, and processes which give fabrics improved durable-press, creasability, and soil-release properties. Cellulosic fabrics are impregnated with a solution made up of ...

W. E. Franklin J. P. Madacsi S. P. Rowland

1974-01-01

5

Hypoxia Press Release and Map - August 1, 2005  

NSDL National Science Digital Library

This EPA press release documents the findings of a 2005 mapping project in the Gulf of Mexico low-oxygen waters. The article notes the extent of the "dead zone" and notes the possible effects of Hurricane Dennis on the hypoxic zone. It also reports a smaller than expected nitrate content in the dead zone, which was attributed to the below average precipitation in the Mississippi River Basin. The press release also features a color map of the dead zone's extent.

Office, Epa- G.

6

JPL Press Release: NASA Astronomers Find Solar System Around Star  

NSDL National Science Digital Library

National Aeronautics and Space Administration astronomers, using the Keck II telescope in Hawaii, along with a team of scientists from the Harvard-Smithsonian Center for Astrophysics and the University of Florida, Gainesville, using the Cerro Tololo Observatory in Chile, "have discovered what appears to be the clearest evidence yet of a budding solar system around a nearby star." HR 4796, about 220 light years from Earth, "shows a swirling disk of dust around the star" that portends the building of a star system. The Jet Propulsion Laboratory press release explains the meaning of the findings.

1998-01-01

7

EXPOSURE AND RELEASE ESTIMATIONS FOR FILTER PRESS AND TRAY DRYER OPERATIONS BASED ON PILOT PLANT DATA  

EPA Science Inventory

Worker exposures and chemical releases associated with a plate-and-frame filter press and a stationary tray dryer were studied in a pilot plant. he equipment was representative of those in a chemical manufacturing plant; the filter press was previously used at a chemical plant, a...

8

Press Releases of Science Journal Articles and Subsequent Newspaper Stories on the Same Topic  

NSDL National Science Digital Library

This article from Journal of the American Medical Association (JAMA) documents how scientific news is made and perpetuated. The authors found evidence that "journal articles described in press releases, in particular those described first or second in the press release, are associated with the subsequent publication of newspaper stories on the same topic." Though not a surprising result, the article offers insights into why and what the public considers important in science.

De Semir, Valdimir.; Uelta, Gemma.; Ribas, Cristina.

1998-01-01

9

Widespread Dysregulation of Peptide Hormone Release in Mice Lacking Adaptor Protein AP-3  

PubMed Central

The regulated secretion of peptide hormones, neural peptides and many growth factors depends on their sorting into large dense core vesicles (LDCVs) capable of regulated exocytosis. LDCVs form at the trans-Golgi network, but the mechanisms that sort proteins to this regulated secretory pathway and the cytosolic machinery that produces LDCVs remain poorly understood. Recently, we used an RNAi screen to identify a role for heterotetrameric adaptor protein AP-3 in regulated secretion and in particular, LDCV formation. Indeed, mocha mice lacking AP-3 have a severe neurological and behavioral phenotype, but this has been attributed to a role for AP-3 in the endolysosomal rather than biosynthetic pathway. We therefore used mocha mice to determine whether loss of AP-3 also dysregulates peptide release in vivo. We find that adrenal chromaffin cells from mocha animals show increased constitutive exocytosis of both soluble cargo and LDCV membrane proteins, reducing the response to stimulation. We also observe increased basal release of both insulin and glucagon from pancreatic islet cells of mocha mice, suggesting a global disturbance in the release of peptide hormones. AP-3 exists as both ubiquitous and neuronal isoforms, but the analysis of mice lacking each of these isoforms individually and together shows that loss of both is required to reproduce the effect of the mocha mutation on the regulated pathway. In addition, we show that loss of the related adaptor protein AP-1 has a similar effect on regulated secretion but exacerbates the effect of AP-3 RNAi, suggesting distinct roles for the two adaptors in the regulated secretory pathway.

Sirkis, Daniel W.; Edwards, Robert H.; Asensio, Cedric S.

2013-01-01

10

To bind or not to bind? Different temporal binding effects from voluntary pressing and releasing actions.  

PubMed

Binding effect refers to the perceptual attraction between an action and an outcome leading to a subjective compression of time. Most studies investigating binding effects exclusively employ the "pressing" action without exploring other types of actions. The present study addresses this issue by introducing another action, releasing action or the voluntary lifting of the finger/wrist, to investigate the differences between voluntary pressing and releasing actions. Results reveal that releasing actions led to robust yet short-lived temporal binding effects, whereas pressing condition had steady temporal binding effects up to super-seconds. The two actions also differ in sensitivity to changes in temporal contiguity and contingency, which could be attributed to the difference in awareness of action. Extending upon current models of "willed action," our results provide insights from a temporal point of view and support the concept of a dual system consisting of predictive motor control and top-down mechanisms. PMID:23741399

Zhao, Ke; Chen, Yu-Hsin; Yan, Wen-Jing; Fu, Xiaolan

2013-01-01

11

To Bind or Not to Bind? Different Temporal Binding Effects from Voluntary Pressing and Releasing Actions  

PubMed Central

Binding effect refers to the perceptual attraction between an action and an outcome leading to a subjective compression of time. Most studies investigating binding effects exclusively employ the “pressing” action without exploring other types of actions. The present study addresses this issue by introducing another action, releasing action or the voluntary lifting of the finger/wrist, to investigate the differences between voluntary pressing and releasing actions. Results reveal that releasing actions led to robust yet short-lived temporal binding effects, whereas pressing condition had steady temporal binding effects up to super-seconds. The two actions also differ in sensitivity to changes in temporal contiguity and contingency, which could be attributed to the difference in awareness of action. Extending upon current models of “willed action,” our results provide insights from a temporal point of view and support the concept of a dual system consisting of predictive motor control and top-down mechanisms.

Zhao, Ke; Chen, Yu-Hsin; Yan, Wen-Jing; Fu, Xiaolan

2013-01-01

12

Corporate Responsibility in Communication: Empirical Analysis of Press Releases in a Conflict  

ERIC Educational Resources Information Center

The paper examines how the tensions of corporate responsibility are articulated and reconciled in a controversial situation of a foreign investment. We conducted a conventionalist analysis on the company press releases in a case where a Finnish forest industry company invested in a pulp mill in South America. The findings show that the use of…

Lehtimaki, Hanna; Kujala, Johanna; Heikkinen, Anna

2011-01-01

13

From Press Release to News: Mapping the Framing of the 2009 H1N1 A Influenza Pandemic  

Microsoft Academic Search

Pandemics challenge conventional assumptions about health promotion, message development, community engagement, and the role of news media. To understand the use of press releases in news coverage of pandemics, this study traces the development of framing devices from a government public health agency's press releases to news stories about the 2009 H1N1 A influenza pandemic. The communication management of the

Seow Ting Lee; Iccha Basnyat

2012-01-01

14

Coverage of Team Science by Public Information Officers: Content Analysis of Press Releases about the National Science Foundation Science and Technology Centers  

ERIC Educational Resources Information Center

This study examines the content of press releases from the National Science Foundation (NSF) Science and Technology Centers (STCs) to determine how public information officers (PIOs) presented the outcomes of centers to journalists and the public. A total of 68 press releases were analyzed for type of news covered, visibility of centers and their…

Graube, Marita; Clark, Fiona; Illman, Deborah L.

2010-01-01

15

[The Universidad de Buenos Aires in the 1970s: analysis of the press release expressing solidarity with Rodolfo Puiggrós].  

PubMed

This article reconstructs the historical context surrounding the emission of a press release by authorities of the Universidad de Buenos Aires, expressing their solidarity with historian and university rector Rodolfo Puiggrós after his resignation. In his term, Puiggrós attempted to fuse the institution's scientific and technological plans with the new development model initiated by Héctor Cámpora and the Peronist movement in 1973. The article makes reference to the project of university transformation promoted by Puiggrós, combining the ideological traditions of Marxism, reformism, and nationalism. A few key points, useful for analyzing the reasons behind Puiggrós's resignation, are presented, and the arguments highlighted within this press release, published by Office of Media and Communications on October 5, 1973, are discussed. PMID:23681463

Recalde, Aritz

2012-12-01

16

Press Releases Issued by Supplements Industry Organisations and Non-Industry Organisations in Response to Publication of Clinical Research Findings: A Case-Control Study  

PubMed Central

Background Dietary supplement use is increasing despite lack of evidence of benefits, or evidence of harm. Press releases issued by the supplements industry might contribute to this situation by using ‘spin’ (strategies to hype or denigrate findings) to distort the results of clinical studies. We assessed press releases issued in response to publication of clinical studies on dietary supplements. Methods and Findings We analyzed 47 supplements industry press releases and 91 non-industry press releases and news stories, generated in response to 46 clinical studies of dietary supplements published between 1/1/2005 and 5/31/2013. The primary outcome was ‘spin’ content and direction. We also assessed disposition towards use of dietary supplements, reporting of study information, and dissemination of industry press releases. More supplements industry press releases (100%) contained ‘spin’ than non-industry media documents (55%, P<0.001). Hyping ‘spin’ scores were higher in industry than non-industry media documents for studies reporting benefit of supplements (median ‘spin’ score 3.3, 95% CI 1.0–5.5 vs 0.5, 0–1.0; P<0.001). Denigratory ‘spin’ scores were higher in industry than non-industry media documents for studies reporting no effect (6.0, 5.0–7.0 vs 0, 0–0; P<0.001) or harm (6.0, 5.5–7.5 vs 0, 0–0.5; P<0.001) from a supplement. Industry press releases advocated supplement use in response to >90% of studies that reported no benefit, or harm, of the supplement. Industry press releases less frequently reported study outcomes, sample size, and estimates of effect size than non-industry media documents (all P<0.001), particularly for studies that reported no benefit of supplements. Industry press releases were referenced by 148 news stories on the websites of 6 organizations that inform manufacturers, retailers and consumers of supplements. Conclusions Dietary supplements industry press releases issued in response to clinical research findings are characterized by ‘spin’ that hypes results that are favourable to supplement use and denigrates results that are not.

Wang, Michael T. M.; Gamble, Greg; Bolland, Mark J.; Grey, Andrew

2014-01-01

17

Thermally induced atomic diffusion at the interface between release agent coating and mould substrate in a glass moulding press  

NASA Astrophysics Data System (ADS)

In a glass moulding press (GMP) for refractive/diffractive hybrid lenses, to improve the service life of nickel-phosphorus (Ni-P) plated moulds, it is necessary to control the diffusion of constituent elements from the mould into the release agent coating. In this study, diffusion phenomena of constituents of Ni-P plating are investigated for two types of release agent coatings, iridium-platinum (Ir-Pt) and iridium-rhenium (Ir-Re), by cross-sectional observation, compositional analysis and stress measurements. The results show that Ni atoms in the plating layer flow from regions of compressive stress to regions of tensile stress. In the case of the Ir-Pt coated mould, the diffusion of Ni is promoted from the grain boundaries between the Ni and Ni3P phases in the plating towards the surface of the Ir-Pt coating. However, in the Ir-Re coated mould, the diffusion of Ni is suppressed because the diffusion coefficient of Ni in the Ir-Re alloy is smaller than that in the Ir-Pt alloy, although the stress state is similar in both cases. By controlling the diffusion of Ni atoms, the use of Ir-Re alloy as a release agent coating for Ni-P plated moulds is expected to lead to a high degree of durability.

Masuda, Jun; Yan, Jiwang; Zhou, Tianfeng; Kuriyagawa, Tsunemoto; Fukase, Yasushi

2011-06-01

18

Press Release: The World Wide Web Consortium Issues SMIL 1.0 as a W3C Recommendation  

NSDL National Science Digital Library

The World Wide Web Consortium (W3C) has issued its first recommendation for Synchronized Multi-media Integration Language. The specification intends to help "bring television-like content to the web, avoiding the limitations for traditional television and lowering the bandwidth requirements for transmitting this type of content over the Internet. With SMIL [pronounced smile], producing audio-visual content is easy; it does not require learning a programming language and can be done using a simple text editor." Easy authorship, accessibility, and improvement of bandwidth efficiency are among a few of the promises that SMIL may bring closer to reality. The site contains a press release and more information about SMIL.

1998-01-01

19

Landslide incidence in the North of Portugal: Analysis of a historical landslide database based on press releases and technical reports  

NASA Astrophysics Data System (ADS)

This work presents and explores the Northern Portugal Landslide Database (NPLD) for the period 1900–2010. NPLD was compiled from press releases (regional and local newspapers) and technical reports (reports by civil protection authorities and academic works); it includes 628 landslides, corresponding to 5.7 landslides per year on average. Although 50% of landslides occurred in the last 35 years of the series, the temporal distribution of landslides does not show any regular increase with time. The relationship between annual precipitation and landslide occurrence shows that reported landslides tend to be more frequent in wetter years. Moreover, landslides occur mostly in the wettest months of the year (December, January and February), which reflects the importance of rainfall in triggering slope instability. Most landslides cause damage that affects people and/or structures; 69.4% of the landslides in Northern Portugal caused 136 fatalities, 173 injured and left 460 persons homeless. More than half of the total landslides (321 landslides) led to railway or motorway closures and 49 landslides destroyed 126 buildings.

Pereira, Susana; Zêzere, José Luís; Quaresma, Ivânia Daniela; Bateira, Carlos

2014-06-01

20

Streptococcus pneumoniae induced c-Jun-N-terminal kinase- and AP-1 -dependent IL-8 release by lung epithelial BEAS-2B cells  

PubMed Central

Background Although pneumococcal pneumonia is one of the most common causes of death due to infectious diseases, little is known about pneumococci-lung cell interaction. Herein we tested the hypothesis that pneumococci activated pulmonary epithelial cell cytokine release by c-Jun-NH2-terminal kinase (JNK) Methods Human bronchial epithelial cells (BEAS-2B) or epithelial HEK293 cells were infected with S. pneumoniae R6x and cytokine induction was measured by RT-PCR, ELISA and Bioplex assay. JNK-phosphorylation was detected by Western blot and nuclear signaling was assessed by electrophoretic mobility shift assay (EMSA) and chromatin immunoprecipitation (ChIP). JNK was modulated by the small molecule inhibitor SP600125 and AP1 by transfection of a dominant negative mutant. Results S. pneumoniae induced the release of distinct CC and CXC, as well as Th1 and Th2 cytokines and growth factors by human lung epithelial cell line BEAS-2B. Furthermore, pneumococci infection resulted in JNK phosphorylation in BEAS-2B cells. Inhibition of JNK by small molecule inhibitor SP600125 reduced pneumococci-induced IL-8 mRNA expression and release of IL-8 and IL-6. One regulator of the il8 promoter is JNK-phosphorylated activator protein 1 (AP-1). We showed that S. pneumoniae time-dependently induced DNA binding of AP-1 and its phosphorylated subunit c-Jun with a maximum at 3 to 5 h after infection. Recruitment of Ser63/73-phosphorylated c-Jun and RNA polymerase II to the endogenous il8 promoter was found 2 h after S. pneumoniae infection by chromatin immunoprecipitation. AP-1 repressor A-Fos reduced IL-8 release by TLR2-overexpressing HEK293 cells induced by pneumococci but not by TNF?. Antisense-constructs targeting the AP-1 subunits Fra1 and Fra2 had no inhibitory effect on pneumococci-induced IL-8 release. Conclusion S. pneumoniae-induced IL-8 expression by human epithelial BEAS-2B cells depended on activation of JNK and recruitment of phosphorylated c-Jun to the il8 promoter.

Schmeck, Bernd; Moog, Kerstin; Zahlten, Janine; van Laak, Vincent; N'Guessan, Philippe Dje; Opitz, Bastian; Rosseau, Simone; Suttorp, Norbert; Hippenstiel, Stefan

2006-01-01

21

Press Release - Dec 1995  

Cancer.gov

Mortality data have shown for several decades that breast cancer death rates are higher in the Northeast than in other regions of the country, particularly the South. But the new analysis demonstrates that the Northeast, Midwest, and West have a similar mortality risk after taking into account factors such as age at first live birth. Moreover, the differences between these regions and the South narrowed after accounting for such factors.

22

Transcriptional regulation of monocyte chemotactic protein-1 release by endothelin-1 in human airway smooth muscle cells involves NF-?B and AP-1  

PubMed Central

Background and purpose: Endothelin-1 (ET-1) is implicated in airway inflammation in asthma, but the mechanisms of its effects are poorly understood. We studied the effect of ET-1 on expression of the chemokine, monocyte chemotactic protein-1 (MCP-1), in primary cultures of human airway smooth muscle cells. Experimental approach: MCP-1 release was measured by elisa. Pharmacological antagonists/inhibitors, reverse transcriptase-polymerase chain reaction (RT-PCR) and Western blotting were used to study ET receptors and kinase cascades. Transcriptional regulation was studied by real-time RT-PCR, transient transfection studies and chromatin immunoprecipitation assay. Major findings were confirmed in cells from three donors and mechanistic studies in cells from one donor. Key results: ET-1 increased MCP-1 release through an ETA and ETB receptor-dependent mechanism. ET-1 increased MCP-1 mRNA levels but not mRNA stability suggesting it was acting transcriptionally. ET-1 increased the activity of an MCP-1 promoter–reporter construct. Serial deletions of the MCP-1 promoter mapped ET-1 effects to a region between ?213 and ?128 base pairs upstream of the translation start codon, containing consensus sequences for activator protein-1 (AP-1) and nuclear factor-?B (NF-?B). ET-1 promoted binding of AP-1 c-Jun subunit and NF-?B p65 subunit to the MCP-1 promoter. Blocking the inhibitor of ?B kinase-2 with 2-[(aminocarbonyl)amino]-5-[4-fluorophenyl]-3-thiophenecarboxamide (TPCA-1) decreased ET-1-stimulated MCP-1 production. p38 and p44/p42 mitogen-activated protein kinases were involved in upstream signalling. Conclusions and implications: ET-1 regulated MCP-1 transcriptionally, via NF-?B and AP-1. The upstream signalling involved ETA, ETB receptors, p38 and p44/p42 mitogen-activated protein kinases. These may be targets for novel asthma therapies.

Sutcliffe, Amy M; Clarke, Deborah L; Bradbury, Dawn A; Corbett, Lisa M; Patel, Jamie A; Knox, Alan J

2009-01-01

23

Attention that Indicators Receive in the Press  

ERIC Educational Resources Information Center

With the release of each edition of Education at a Glance, the Office for Economic Co-operation and Development (OECD) prepares a press briefing to be used for the international press release and which individual countries in preparing their national press releases can also use. Similarly, the European Union prepares a summary, not for use at the…

Hendriks, Maria; Barzano, Giovanna; Brumana, Emanuela; Cremonesi, Claudia

2004-01-01

24

Drill Presses.  

ERIC Educational Resources Information Center

These instructional materials provide an orientation to the drill press for use at the postsecondary level. The first of seven sections lists seven types of drill presses. The second section identifies 14 drill press parts. The third section lists 21 rules for safe use of drilling machines. The fourth section identifies the six procedures for…

Engelbrecht, Nancy; And Others

25

The U.S. Government's Assistance to the AP's World-Wide Expansion: 1912-1948.  

ERIC Educational Resources Information Center

A study of the extent of the diplomatic and commercial assistance provided by the United States government to the Associated Press (AP) from 1912 to 1948 shows AP's manager, Kent Cooper, to be less a champion of the free press than an efficient captain of industry in expanding AP influence across the globe. Early in the twentieth century, British,…

Renaud-Komiya, Jean-Luc

26

SIO Oceans 2003 Press Release  

NSF Publications Database

... September 22-25, 2003 Town & Country Hotel, San Diego http://oceans2003.org Contacts: Deam Given ... Hotel. Register through the Oceans2003 Web site, http://oceans2003.org/, or call the hotel directly ...

27

CRCHD - News Releases  

Cancer.gov

CRCHD - News Releases Home News and Events News Releases News Releases E-bulletin News Stories Spotlights Meetings & Events Press Kit News Releases & Articles 2012 New! CRCHD PNRP Grantees Publish Research

28

The Associated Press Stylebook and Libel Manual. Fully Updated and Revised.  

ERIC Educational Resources Information Center

Pointing out that the style of the Associated Press (AP) defines clear writing, this revised edition of the practical and much-used AP stylebook is designed to be an essential handbook for all writers, editors, and students. The stylebook contains over 5000 entries laying out the AP's rules on grammar, spelling, punctuation, and usage. It gives…

Goldstein, Norm, Ed.

29

CRCHD - News Releases  

Cancer.gov

CRCHD - News Releases Home News and Events News Releases Health Disparities News & Articles E-bulletin News Stories & Interviews CRCHD Spotlights Meetings & Events Press Kit News Releases & Articles 2012

30

The GALFA-HI Survey: Toward the Second Data Release  

NASA Astrophysics Data System (ADS)

The GALFA-HI Survey uses 21-cm spectral line data recorded with the Arecibo L-band Feed Array (ALFA), in an effort to map the neutral hydrogen content of the Galaxy and its nearby environment. The first full public release of data (Peek et al. 2011, ApJS in press) covers approximately 7500 square degrees, from observations spanning the epoch of May 2005 to February 2009. The second data release will include data from GALFA-HI observations to the end of 2010. We will describe the attributes of the survey, and most importantly, how to gain access to the data.

Douglas, Kevin A.; Peek, J. E. G.; Grcevich, J.; Saul, D.; Lee, M.; Pingel, N.; Korpela, E. J.; Stanimirovic, S.; Putman, M. E.; Gibson, S. J.; Heiles, C. E.

2011-05-01

31

Isothermal Forging and Its Effect on the Microstructure of Powder Route Nickel Alloy AP1.  

National Technical Information Service (NTIS)

The influence of initial billet hot isostatic pressing treatment and forging parameters on the microstructure of isothermally formed powder AP1 were investigated. Strain, strain rate, and forging temperature were varied using a microprocessor controlled s...

C. Wilkinson

1986-01-01

32

Small Press Roundup  

ERIC Educational Resources Information Center

A small press is, essentially, an enterprise dedicated to overcoming routine publishing attitudes. Reviewing services, reference aids, bookstores, and publishers' addresses are included in this review of small press publications for 1973. (Author/SM)

Katz, Bill

1973-01-01

33

29 CFR 1910.217 - Mechanical power presses.  

Code of Federal Regulations, 2010 CFR

...clutches. (i) The clutch shall release and the brake shall...brake engagement and clutch release is effected by spring...supply for pneumatic clutch/brake control valves... (4) Flywheels and bearings. Presses...

2010-07-01

34

29 CFR 1910.217 - Mechanical power presses.  

Code of Federal Regulations, 2010 CFR

...clutches. (i) The clutch shall release and the brake shall...brake engagement and clutch release is effected by spring...supply for pneumatic clutch/brake control valves... (4) Flywheels and bearings. Presses...

2009-07-01

35

PSAT and AP Success.  

ERIC Educational Resources Information Center

Through evaluation of 73 eleventh-grade students over three years, explores the extent to which standardized test scores and other academic factors predict success on the Advanced Placement (AP) exam in U.S. history. Finds that standardized scores, grade point average, and anticipated college majors are closely related to AP success. (CMK)

Palin, Raymond J.

2001-01-01

36

Opening AP to All  

ERIC Educational Resources Information Center

This article reports on a school's effort to open Advanced Placement (AP) to all by challenging its students to take the leap into AP courses. Samuel W. Wolfson High School, on the south side of Jacksonville, Florida, is one of 27 schools in five cities across the country that chose to participate in a College Board initiative called EXCELerator.…

Gewertz, Catherine

2008-01-01

37

The Global University Press  

ERIC Educational Resources Information Center

The modern world's understanding of American university press has long been shaped by university-press books. American university-press books are good international advertisements for the universities whose logos grace their spines. The growth of transnational scholarship and the expansion of digital communications networks are converging in ways…

Dougherty, Peter J.

2012-01-01

38

Censorship of the Press.  

National Technical Information Service (NTIS)

This paper examines censorship of the American Press: past, present, and outlook for the future. The role of the press in the United States is viewed from the perception of the journalist and the government. Two recent free-press conflicts are reviewed in...

R. F. Gibbs, L. W. Freeman

1972-01-01

39

Attacks on the Press in 2001  

NSDL National Science Digital Library

Released by the Committee to Protect Journalists (CPJ), a nonpartisan, nonprofit organization established to "monitor abuses against the press and promote press freedom around the world," Attacks on the Press 2001 documents the deaths, imprisonment, and abuses of journalists around the world within the past year. Prefaced by CPJ board member Anne Garrels with an introduction by CPJ's executive director Ann Cooper, the report contains an overview of media attacks arranged by country, along with three special press freedom reports on Syria, Burma, and Colombia. In addition, the report contains a Ten Worst Enemies of the Press section that focuses attention on individual leaders responsible for the world's worst abuses against the media. Topping the list are Supreme Leader Ayatollah Ali Khamenei of Iran, President Jiang Zemin of China, and Liberian president Charles Taylor.

2002-01-01

40

Attacks on the Press in 2000  

NSDL National Science Digital Library

This recently published survey reports on the harassment, imprisonment, and death of journalists worldwide. The report is comprised of regional overviews, country summaries, and individual documented cases. There are also special sections on journalists murdered or imprisoned in the last year, the International Press Freedom Awards of 2000 (given to courageous journalists), and a press release, as well as individual reports on the state of press freedom in China, Russia, and Venezuela. The report may be viewed in HTML or .pdf formats. Earlier editions of this annual report are also available on this site, back to 1996. The preface of this most recent edition was written by Peter Arnett.

2001-01-01

41

AP Chemistry: Course Revisions  

NSDL National Science Digital Library

In Fall 2013, The Advanced Placement Program will be replacing the existing AP Chemistry course with a new chemistry curriculum designed to foster greater conceptual understanding and more time engaged in scientific practices. This website offers an array of resources to support teachers and school administrators in adopting the new AP Chemistry. The framework shifts away from a traditional "content coverage" model to one that focuses on six key ideas in chemistry. Especially noteworthy is the greater emphasis on visualization of the particle nature of matter. Each learning objective explicitly combines content and one or more "thinking skills", intended to promote greater time engaged in scientific inquiry with less focus on mathematical routines. Resources available on this web page include the Curriculum Framework, FAQ's on the new AP Chemistry, Planning and Pacing Guides, teachers' forum, examples, and reference material on inquiry instruction. The changes to each course were guided by National Research Council and National Science Foundation recommendations, following several years of collaborations among university educators and master AP teachers. Editor's Note: The AP Physics course has also undergone major revision, replacing AP Physics B with two year-long courses, slated for adoption in Fall 2014. See "Related Materials" for a link to the College Board's website on AP Physics revisions.

42

APS study of directed energy weapons  

Microsoft Academic Search

Before being considered seriously for defense against potential ballistic missile attacks, all existing candidates for directed energy weapons (DEW) require improvement by a factor of at least 100 in power output and beam quality, according to an American Physical Society (APS) report released April 23.

Barbara T. Richman

1987-01-01

43

APS study of directed energy weapons  

NASA Astrophysics Data System (ADS)

Before being considered seriously for defense against potential ballistic missile attacks, all existing candidates for directed energy weapons (DEW) require improvement by a factor of at least 100 in power output and beam quality, according to an American Physical Society (APS) report released April 23.

Richman, Barbara T.

44

APS Science 2006.  

SciTech Connect

In my five years as the Director of the Advanced Photon Source (APS), I have been fortunate to see major growth in the scientific impact from the APS. This year I am particularly enthusiastic about prospects for our longer-term future. Every scientific instrument must remain at the cutting edge to flourish. Our plans for the next generation of APS--an APS upgrade--got seriously in gear this year with strong encouragement from our users and sponsors. The most promising avenue that has emerged is the energy-recovery linac (ERL) (see article on page xx), for which we are beginning serious R&D. The ERL{at}APS would offer revolutionary performance, especially for x-ray imaging and ultrafast science, while not seriously disrupting the existing user base. I am very proud of our accelerator physics and engineering staff, who not only keep the current APS at the forefront, but were able to greatly impress our international Machine Advisory Committee with the quality of their work on the possible upgrade option (see page xx). As we prepare for long-term major upgrades, our plans to develop and optimize all the sectors at APS in the near future are advancing. Several new beamlines saw first light this year, including a dedicated powder diffraction beamline (11-BM), two instruments for inelastic x-ray scattering at sector 30, and the Center for Nanoscale Materials (CNM) Nanoprobe beamline at sector 26. Our partnership in the first x-ray free-electron laser (LCLS) to be built at Stanford contributes to revolutionary growth in ultrafast science (see page xx), and we are developing a pulse chirping scheme to get ps pulses at sector 7 of the APS within a year or so. In this report, you will find selected highlights of scientific research at the APS from calendar year 2006. The highlighted work covers diverse disciplines, from fundamental to applied science. In the article on page xx you can see the direct impact of APS research on technology. Several new products have emerged from work at the APS, to complement the tremendous output of work in basic science, which often has payoff in technology but over decades rather than years. Highlights in this report also reflect the relevance of APS work to Department of Energy missions, for example a route to more efficient fuel cells (page xx mr-88-073113) addresses the energy challenge, and natural approaches to cleaning up the environment.

Gibson, J. M.; Fenner, R. B.; Long, G.; Borland, M.; Decker, G.

2007-05-24

45

AP Central: AP Biology Course Home Page  

NSDL National Science Digital Library

For students and educators seeking to learn more about the world of biology, this website is the perfect resource. Created by the College Board, this site contains information designed to help individuals prepare for the AP Biology examination. The resources here include a guide to conducting investigative labs in the classroom, an overview of quantitative skills, and several other preparatory items. In the Classroom Resources area, visitors can look over curriculum modules and field trip suggestions among other tools. The "Related Articles" section features pieces such as "Mendel's Legacy," "Gastrulation: Shaping the Embryo," and "DNA and Computers-A Marriage Made in Heaven." The site is rounded out by a series of course overviews crafted specially for AP Biology instructors.

2013-04-05

46

The Prison Press.  

ERIC Educational Resources Information Center

The prison press in the United States operates under varying degrees of First Amendment freedom. Court decisions have been varied, and have not resolved whether convicts can produce or receive publications without censorship by prison officials. Until about 1970, censorship of the prison press was rarely challenged. Most newspapers and magazines…

Hausman, John

47

Presidential Press Conferences.  

ERIC Educational Resources Information Center

This report discusses the background, advantages, and disadvantages of the televised presidential press conference, citing the opinions of numerous newspaper and magazine writers. After presenting a brief overview of the presidential press conference from the administration of Theodore Roosevelt to that of Eisenhower, the report discusses the type…

Moore, Susan E.

48

Mars Exploration Rover Mission: Press Release Images  

NSDL National Science Digital Library

The public can now view the amazing, newly collected images of Mars thanks to this Mars Exploration Rover Mission website. The first images, made available on January 4, 2004, are black and white pictorials of the rover on the surface of Mars. On January 6, 2004, this website provided users with the first color images of Mars. Alongside each image, the NASA team has provided users with straightforward explanations. Everyone will enjoy these images of Spirit's descent, Mars' wind-polished rocks, the Martian Horizon, and much more.

49

Center for Astrophysics: 2007 Press Release Images  

NSDL National Science Digital Library

This multimedia gallery, from the Harvard-Smithsonian Center for Astrophysics (CfA), contains imagery of astronomical objects by CfA researchers. Animations and artist's conceptions of astronomical features are included as well as infrared, ultraviolet, radio, X-ray, and optical images. Archives present the image galleries from previous years.

2007-05-31

50

Trade Unions about the Press.  

ERIC Educational Resources Information Center

This paper analyzes the attitudes of three Swedish trade unions toward the press. Local representatives of the unions answered a questionnaire about their contact with the local press, the press's impact on public opinion, fairness of press reporting, the press's fulfillment of its duties in informing the public, and future control of mass media.…

Strid, Jan

51

The Press Freedom Database  

NSDL National Science Digital Library

Developed by the Committee to Protect Journalists (CPJ), The Press Freedom Database contains case histories of documented press freedom violations against journalists and media organizations worldwide as well as annual CPJ reports on the violations in specific countries and regions. The case histories document the circumstances in which journalists have been attacked, killed, expelled, censored, harassed, threatened, and/or imprisoned. The database is searchable by journalist name, news organization, type of organization, date, country, or region. Currently, the database, which is updated weekly, contains over 2,000 reports of press freedom violations, spanning from 1993 to the present.

52

Advancing beyond AP Courses  

ERIC Educational Resources Information Center

A quiet revolution is picking up steam in the nation's private secondary schools, with broad implications for college admissions and for teaching and learning on both sides of the transition from high school to college. About 50 of the nation's leading college-preparatory schools have opted out of the College Board's Advanced Placement (AP

Hammond, Bruce G.

2009-01-01

53

APS power supply controls  

SciTech Connect

The purpose of this document is to provide comprehensive coverage of the APS power supply control design. This includes application software, embedded controller software, networks, and hardware. The basic components will be introduced first, followed by the requirements driving the overall design. Subsequent sections will address each component of the design one by one. Latter sections will address specific applications.

Saunders, C.W.; Despe, O.D.

1994-03-31

54

Polish Law Governing the Press.  

National Technical Information Service (NTIS)

Uniform text of Law governing the Press of 1/1984 as amended in 1988, 1989, and 1990. The law contains provisions pertaining to rights and responsibilities of journalists; the press council; organization of press activities; rectifications and responses; ...

1992-01-01

55

Comparison of expression and enzymatic properties of Aspergillus oryzae lysine aminopeptidases ApsA and ApsB.  

PubMed

The apsA and apsB genes encoding family M1 aminopeptidases were identified in the industrial fungus Aspergillus oryzae. The apsB was transcriptionally up-regulated up to 2.5-fold in response to the deprivation of nitrogen or carbon sources in growth media, while up-regulation of apsA was less significant. The encoded proteins were bacterially expressed and purified to characterize their enzymatic properties. ApsA and ApsB were optimally active at pH 7.0 and 35 °C and stable at pH ranges of 6-10 and 4-10, respectively, up to 40 °C. The enzymes were inhibited by bestatin and EDTA, as has been reported for family M1 aminopeptidases that characteristically contain a zinc-binding catalytic motif. Both enzymes preferentially liberated N-terminal lysine, which is an essential amino acid and an important additive to animal feed. Enzymes that efficiently release N-terminal lysine from peptides could be useful for food and forage industries. Examination of the reactivity toward peptide substrate of varying length revealed that ApsB exhibited broader substrate specificity than ApsA although the reactivity of ApsB decreased as the length of peptide substrate decreased. PMID:22806190

Marui, Junichiro; Matsushita-Morita, Mayumi; Tada, Sawaki; Hattori, Ryota; Suzuki, Satoshi; Amano, Hitoshi; Ishida, Hiroki; Yamagata, Youhei; Takeuchi, Michio; Kusumoto, Ken-Ichi

2012-08-01

56

Physics AP B I  

NSDL National Science Digital Library

HippoCampus, a project of the Monterey Institute for Technology and Education (MITE), seeks to provide âÂÂhigh-quality, multimedia content on general education subjects to high school and college students.â This course, Advanced Placement Physics B I, is part one of a two semester course and contains study materials, lessons, and textbooks to help students prepare for the College Board AP Physics exam. Two course units, containing nine chapters in total, cover topics in Newtonian mechanics, fluid mechanics and thermal physics. Many of the chapters feature multimedia resources that employ a variety of interactive activities to help students absorb information. This is an excellent self-paced tool for students to use while preparing for the AP Physics exam, or as supplementary material for a physics course.

2008-07-08

57

APS Science 2007.  

SciTech Connect

This report provides research highlights from the Advanced Photon Source (APS). Although these highlights represent less than 10% of the published work from the APS in 2007, they give a flavor of the diversity and impact of user research at the facility. In the strategic planning the aim is to foster the growth of existing user communities and foresee new areas of research. This coming year finds the APS engaged in putting together, along with the users, a blueprint for the next five years, and making the case for a set of prioritized investments in beamlines, the accelerator, and infrastructure, each of which will be transformational in terms of scientific impact. As this is written plans are being formulated for an important user workshop on October 20-21, 2008, to prioritize strategic plans. The fruit from past investments can be seen in this report. Examples include the creation of a dedicated beamline for x-ray photon correlation spectroscopy at Sector 8, the evolution of dedicated high-energy x-ray scattering beamlines at sectors 1 and 11, a dedicated imaging beamline at Sector 32, and new beamlines for inelastic scattering and powder diffraction. A single-pulse facility has been built in collaboration with Sector 14 (BioCARS) and Phil Anfinrud at the National Institutes of Health, which will offer exceptionally high flux for single-pulse diffraction. The nanoprobe at Sector 26, built and operated jointly by the Argonne Center for Nanoscale Materials and the X-ray Operations and Research (XOR) section of the APS X-ray Science Division, has come on line to define the state of the art in nanoscience.

Not Available

2008-05-30

58

Four Theories of the Press.  

ERIC Educational Resources Information Center

A systematic understanding of the press requires an understanding of the social and political structures within which the press operates. This book discusses four theories that have determined the kind of press the Western world has had: authoritarian, libertarian, socially responsible, and Soviet communist. Each chapter discusses press…

Siebert, Fred S.; And Others

59

The Berkeley Electronic Press  

NSDL National Science Digital Library

A new electronic publishing company, The Berkeley Electronic Press (bepress.com), was launched in December 2000 by three University of California, Berkeley economics professors. The press was created in reaction to the frustration over the traditional publishing world by bepress.com founder Bob Cooter, the Herman Selvin Professor of Law at UC-Berkeley. Bepress.com features four scholarly journals The B. E. Journals in Theoretical Economics, The B. E. Journals in Macroeconomics, The B. E. Journals in Economic Analysis and Policy, and Global Jurist. For a limited time only, the full text for all of these journals is free.

60

Press-On Optics  

ERIC Educational Resources Information Center

The article discusses the design, application, and clinical uses of press-on optics which are descirbed as 1 millimeter thick, flexible lenses or prisms that may be produced in virtually any desired plus or minus dioptric power as ophthalmic lenses, or in any range of usable prism diopter power. (GW)

Thorson, Jon C.

1972-01-01

61

America's Enduring Ethnic Press.  

ERIC Educational Resources Information Center

Studies of the history of newspapers in the United States have virtually ignored the ethnically oriented, foreign language press. This gap in journalistic investigation should be filled by considering the two conflicting roles which ethnic newspapers fill: assimilation of the ethnic group into the mainstream of American culture and maintenance and…

Marzolf, Marion

62

Tower Press Camera  

USGS Multimedia Gallery

"4x5" enclosure camera with Rangefinder and Wollensak Raptar lens serial #A18388, 62 mm, 1950s-60s. Manufactured by Busch Optical Manufacturing Company, Chicago, Illinois (also known as Busch Precision Camera Corporation). The company was famous for its versatile press cameras which featured an opti...

2009-07-22

63

Containment integrity analysis for the Westinghouse Advanced AP600  

SciTech Connect

Since 1987, Westinghouse has been performing containment cooling analyses in support of the advanced AP600 plant design. This analysis effort was intended to verify the feasibility of the passive containment cooling system (PCCS) features of the AP600 design, which is being jointly developed by Westinghouse, Burns and Roe Company, and Avondale Industries. To support this goal, the response of the AP600 containment has been analyzed for a large-break loss-of-coolant-accident (LOCA) and for a large steam line break (SLB). These cases were chosen based on the characteristic mass and energy releases each scenario would impose on the containment, with LOCA releases taxing the long-term heat-removal aspects while the SLB release typically defines the limiting short-term response. The transient results indicate that the PCCS design is feasible and capable of removing sufficient heat to limit containment pressure to within acceptable limits.

Gagnon, A.F.; Howe, K.S. (Westinghouse Electric Corporation, Pittsburgh, PA (USA))

1989-11-01

64

AP1 function and regulation  

Microsoft Academic Search

AP-1 (activating protein-1) is a collective term referring to dimeric transcription factors composed of Jun, Fos or ATF (activating transcription factor) subunits that bind to a common DNA site, the AP-1-binding site. As the complexity of our knowledge of AP-1 factors has increased, our understanding of their physiological function has decreased. This trend, however, is beginning to be reversed due

Michael Karin; Zheng-gang Liu; Ebrahim Zandi

1997-01-01

65

AP Physics 1 and AP Physics 2: Course Revisions  

NSDL National Science Digital Library

In Fall 2014, The Advanced Placement Program will be replacing AP Physics B with a two-year sequence designed to foster greater depth of conceptual understanding and more time engaged in inquiry-based learning. The new courses, AP Physics 1 and AP Physics 2, will be equivalent to the first and second semesters of a typical introductory, algebra-based college physics course. This website informs physics teachers and school administrators about what's changing in AP physics, from course scope to exam design. The framework shifts away from a traditional "content coverage" model to one that focuses on key ideas in introductory physics. The approach was developed to allow greater time engaged in the practice of science, with less focus on mathematical routines. Resources available on this web page include the Curriculum Framework, FAQ's on the new AP Physics, examples, and reference material on inquiry instruction. The changes to each course were guided by National Research Council and National Science Foundation recommendations, following several years of collaborations among university educators and master AP teachers. Editor's Note: The AP Chemistry course has also undergone major revision, slated for adoption in Fall 2013. See Related Materials for a link to the College Board's web page on AP Chemistry revisions.

66

AP Calculus BC II  

NSDL National Science Digital Library

Presented by HippoCampus, a project of the Monterey Institute for Technology and Education, this free online course covers all of the material outlined by the College Board as necessary to prepare students to pass the AP Calculus BC exam. This course is divided into two semesters and this course is the second of those two semesters, it is designed to "acquaint you with calculus principles such as derivatives, integrals, limits, approximation, applications and modeling, and sequences and series." The course is separated into three units: antiderivatives and definite integrals; application of integrals; and infinite sequences and series. Each lesson has objectives, readings, multimedia lectures, and assessments with answers. The site is also indexed by subject, which can be browsed alphabetically or sequentially. It is a great place for students to enhance their calculus skills or for educators to find supplementary materials for the classroom.

2008-07-09

67

Press Relations of Terrorist Organizations.  

ERIC Educational Resources Information Center

Explores and illustrates the different types of press relations commonly undertaken by terrorist organizations. Argues that large and small groups both engage in publicity efforts, but employ different patterns of press relations activities. (SR)

Picard, Robert G.

1989-01-01

68

New Prairie Press  

NSDL National Science Digital Library

The New Prairie Press (NPP) was founded at the Kansas State University Libraries in 2007. Created as an open access publishing venture, they focus their work on journals in the humanities, social sciences, and arts. Currently, they publish several journals that include The Baltic International Yearbook of Cognition, Logic and Communication and the Online Journal of Rural Research & Policy. They also provide editorial support to journals such as The Lion and the Unicorn, which is published by Johns Hopkins University Press. Visitors to the site can read issues from all five of their main journals, and they can also register to receive updates and create lists of their favorite articles. Additionally, users can search all of the journals at one time with the "Journal Content" search engine.

69

Inner City Press  

NSDL National Science Digital Library

Based in the South Bronx, the Inner City Press has been publishing a newspaper focused on low-income neighborhoods nationwide since 1987. A few months ago, the organization went online with a weekly publication featuring original and engaging investigative and analytical pieces from a selection of beats, including the Federal Reserve, Community Reinvestment, Insurance Redlining, Wall Street, Environmental Justice, and Banks, among others. The most recent issue (August 30) includes concise reports on predatory lending, the economic crisis in Ecuador, press leaks and the Federal Reserve, and a round-up of bank news. The site also provides overviews and related resources for Community Reinvestment, the Inner City Public Interest Law Center, Environmental Justice, Insurance Redlining, and related topics.

70

Rodale Press (A)  

Microsoft Academic Search

DOESN'T MEET STANDARDSMaria Rodale, 32-year-old heir apparent to Rodale Press (Runners' World, Bicycling, Organic Gardening, Prevention Magazine) is about to begin a sabbatical to prepare herself for her as-yet-to-be-determined leadership role. She must consider several challenges: ascertaining her new job and convincing the chairman (her mother) to share power, gaining the confidence of more-experienced senior management, navigating family (shareholder) politics,

L. Bourgeois; Catherine Elliott; Marcien Jenckes; Daren Samuels

71

Executive Committee Press Office  

NASA Astrophysics Data System (ADS)

While expecting a huge increase of interest in the IAU as a result of the planet definition issue on the agenda of the IAU XXVI General Assembly, Prague, Czech Republic, August 2006, the Executive Committee appointed Lars Lindberg Christensen as Press Officer in June 2006. He will stay on the job till at least the IAU XXVII General Assembly in Rio de Janeiro, Brazil, August 2009.

Christensen, Lars Lindberg

72

AP-42 REVISION: COKE OVENS  

EPA Science Inventory

The document "Compilation of Air Pollutant Emission Factors" (AP-42) has been published by the U. S. Environmental Protection Agency (EPA) since 1972. Supplements to AP-42 have been routinely published to add new emission source categories and to update existing emission factor...

73

APS controls overview  

SciTech Connect

The APS accelerator control system described in this report is a distributed system consisting of operator interfaces, a network, and interfaces to hardware. The operator interface is a UNIX-based workstation with an X-windows graphical user interface. The workstation may be located at any point on the facility network and maintain full functionality. The user has the ability to generate and alter control displays and to access the alarm handler, the archiver, interactive control programs, custom code, and other tools. The TCP/EP networking protocol has been selected as the underlying protocol for the control system network. TCP/EP is a commercial standard and readily available from network hardware vendors. Its implementation is independent of the particular network medium selected to implement the controls network. In the development environment copper Ethernet is the network medium; however, in the actual implementation a fiber-based system using hub technology will be utilized. The function of the network is to provide a generalized communication path between the host computers, operator workstations, input/output crates, and other hardware that comprise the control system.

NONE

1996-02-01

74

The National Academics Press  

NSDL National Science Digital Library

This is the home page of The National Academies Press (NAP), created by the National Academies to publish the reports issued by the National Academy of Sciences, the National Academy of Engineering, the Institute of Medicine, and the National Research Council, all operating under a charter granted by the Congress of the United States. The NAP publishes more than 200 books a year on a wide range of topics in science, engineering, and health, capturing the most authoritative views on important issues in science and health policy. In 2011, NAP made thousands of reports available for free download. Access to the cost-free pdf versions is available to registered NAP users.

2012-06-19

75

Bayesian social learning, conformity, and stubbornness: evidence from the AP top 25  

Microsoft Academic Search

The recent nonexperimental literature on social learning focuses on showing that observational learning exists, that is, individuals do indeed draw inferences by observing the actions of others. We take this literature a step further by analyzing whether individuals are Bayesian social learners. We use data from the Associated Press (AP) U.S. College Football Poll, a weekly subjective ranking of the

Daniel F. Stone; Basit Zafar

2010-01-01

76

Delta XTE Press Briefing  

NASA Technical Reports Server (NTRS)

Live coverage of the pre-launch Delta X-Ray Timing Explorer (XTE) press briefing is presented. George Diller, NASA Public Affairs, introduces the panel. The panel consists of Floyd Curington, NASA Launch Manager, Kennedy Space Center; David Mitchell, Launch Vehicle Manager, NASA Goddard Space Flight Center; Dale Schulz, Mission Director, XTE Project Manager Goddard Space Flight Center; Dr. Hale Bradt, XTE Principle Investigator, Massachusetts Institute of Technology (MIT); and Joel Tumbiolo, Launch Weather Officer, Department of the Air Force. The launch of the Delta XTE spacecraft atop the Delta 230 expendable launch vehicle is discussed. Once lofted into orbit, the XTE spacecraft will embark on a two-year mission to carry out an in-depth study of x-ray sources in the universe. Floyd Curington gives the lift-off schedule, fueling, and countdown of the spacecraft. David Mitchell discusses the launch sequence and spacecraft separation. Dale Schulz presents viewcharts of the instrument side of the XTE. Dr. Hale will be studying compact stars such as light dwarfs, neutron stars and quasars. Joel Tumbiolo presents the weather forecast for the December 10, 1995 launch. The press briefing ends with a question and answer period.

1995-01-01

77

Iran Weekly Press Digest  

NSDL National Science Digital Library

The Iran Weekly Press Digest, a weekly review of the Iranian press in English, contains a number of articles on the summit of the Organisation of the Islamic Conference and its significance for Iran in its archived and current issues. The eighth summit of the Organisation of the Islamic Conference was recently held in Tehran, Iran. Iran recently hosted representatives from 55 countries to a three-day Muslim summit in Tehran in a move which is being seen as a new phase in the country's re-emergence after years of relative isolation. The acceptance of Iran's invitations by senior figures from former enemies such as Saudi Arabia and Iraq has been portrayed by Iranian leaders and many others as a strong setback for US attempts to politically quarantine that country. Representatives considered 142 resolutions prepared by foreign ministers on issues including Middle East peace, regional conflicts, terrorism and human rights. However, perhaps the most significant outcome of the summit has been a reintroduction of Iran into the Muslim community of nations. Capitalizing on current anti-American sentiments and the recent election of a relatively moderate president, Iran hopes to rebuild its relationships with its neighbors and once again become a regional leader, a position it held for approximately 3000 years.

1997-01-01

78

APS Minority Travel Fellows Attend the 2010 APS Conferences  

NSDL National Science Digital Library

From The Physiologist. Four travel fellows received funding to attend the 2010 APS Intersociety Meeting, ÃÂGlobal Change and Global Science: Comparative Physiology in a Changing World,ÃÂ from August 4-7, 2010 in Westminster, CO. Four travel fellows received funding to attend the APS Conference, ÃÂInflammation, Immunity and Cardiovascular Disease,ÃÂ from August 25-28, 2010 also in Westminster, CO. The application reviews were led by Committee Member, Johana Vallejo-Elias.

2010-12-01

79

AP Central: Genetics Accountability Box  

NSDL National Science Digital Library

With this simple demonstration, teachers can present the concepts of genetic diseases, probability, and ethics. Students can discuss other genetic problems using this model that are align with questions found on the AP Biology exam.

Carl Koch (Benedictine University and Waubonsee Community College;)

2003-06-01

80

Learning about Antiphospholipid Syndrome (APS)  

MedlinePLUS

... travel through the blood stream, causing embolic events. Lupus and Other Autoimmune Disorders APS is classified within ... have an additional autoimmune disorder, most commonly systemic lupus erythematosus (SLE). About 30-40 percent of individuals ...

81

APS Initiatives for Broadening Participation  

NASA Astrophysics Data System (ADS)

Women currently earn only about 20% of physics degrees, while African Americans and Hispanic Americans combined -- representing 34% of the US population in their 20's -- earn only 9% and 5-6% of the Bachelor and Doctoral degrees respectively. To address these disparities, and improve conditions for everyone who studies physics, the APS devotes significant resources to addressing these concerns and to enabling individuals and groups to work with the APS to advance these goals. In this presentation, I will outline several of our most significant programs, give data that informs decisions to adopt programs, and describe current plans. Included in this is the new APS Bridge Program (www.APSBridgeProgram.org) for increasing underrepresented minority participation at the PhD level, the APS Conferences for Undergraduate Women in Physics (go.aps.org/cuwip), and the APS Minority Scholars Program (www.MinoritiesInPhysics.org). Please bring your ideas and concerns for how we might improve participation for all.

Hodapp, Theodore

2013-03-01

82

Open Humanities Press  

NSDL National Science Digital Library

As more and more journals elect to move to an open-source model, it is delightful to learn about the existence of the Open Humanities Press (OHP). Their mission is "to make leading works of contemporary critical thought freely available worldwide." First-time visitors will want to look over the "About OHP" section before delving into the rest of the site. Afterwards, they should feel free to look through one of their seven journals, which include "Cosmos and History", "Culture Machine", "Film-Philosophy", and "Fibreculture". While all of the journals are worth a look, the "Film-Philosophy" journal is particularly compelling, and visitors can browse through issues back to 1997. Finally, visitors can also learn about submitting their work for consideration and also take in a few essays about the guiding principles and history of the OHP.

83

Stony Brook Press  

NSDL National Science Digital Library

The State University of New York at Stony Brook has an impressive set of digital collections spanning poetry, history, and geography. This particular section of the digital initiative, known as DSpace, brings together past issues of the Stony Brook Press. This institutional journal is published every two weeks, and this particular archive contains over 560 issues. It's far from dry as it reports on everything from new literary endeavors to changes within the faculty. As one of the largest schools in the state system, this school has undergone many changes in the past twenty years, and this publication is a great way to learn more about the school's history. Also it is easy to search through past issues via the advanced search option.

84

PRESS SHOP. SEVEN BLISS PRESSES STAMP OUT A VARIETY OF ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

PRESS SHOP. SEVEN BLISS PRESSES STAMP OUT A VARIETY OF CARTRIDGE AND SHELL CASINGS. THIS DEPARTMENT WAS TRANSFORMED FROM A MONEY-LOSING OPERATION TO A PROFIT CENTER UNDER THE FIRST WORKER-MANAGED QUALITY CIRCLE IN THE PLANT. - American Brass Foundry, 70 Sayre Street, Buffalo, Erie County, NY

85

CIDER PRESS, LOOKING SOUTHEAST ACROSS THE SCHUYLKILL RIVER. THIS PRESS, ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

CIDER PRESS, LOOKING SOUTHEAST ACROSS THE SCHUYLKILL RIVER. THIS PRESS, CARVED OUT OF A LARGE BOULDER AT THE RIVERS EDGE, PROBABLY DATES FROM THE LIFETIME OF JOHN BARTRAM, IF NOT TO THE SWEDISH SETTLERS BEFORE HIM. THE IRON FENCE IS A NINETEENTH-CENTURY ADDITION - John Bartram House & Garden, 54th Street & Lindbergh Boulevard, Philadelphia, Philadelphia County, PA

86

The CIA and the Press.  

ERIC Educational Resources Information Center

The involvement of the Central Intelligence Agency (CIA) with both United States and foreign news media has been recorded in numerous publications. This report reviews the important aspects of the CIA-press relationships as they have appeared in print and discusses the implications of these relationsihps for the credibility of the press. Media…

Carvalho, Bernardo A.

87

Cylindrical claw clamp has quick release feature  

NASA Technical Reports Server (NTRS)

Claw clamp grasps cylindrical shapes by pressing its jaws around the object. The clamp is released by retraction of a release pin which extends beyond the clamp handle on both sides for better purchase.

Goodwin, G. D.

1966-01-01

88

AP Chemistry Course Home Page  

NSDL National Science Digital Library

For people with a penchant for benzene rings and other topics, the AP Chemistry Course site is a great resource. Designed for both educators and students, the site contains resources for teaching to the AP exam as well as a wealth of other items. Interested parties should explore the Classroom Resources where they will find seven different lab activities, such as "Misconceptions and Issues in Quantum Theory" and "Women Scientists of the Manhattan Project.â Additionally, the site features Other Core Resources which includes an open forum for educators along with some basic overviews for crafting a one-semester course in chemistry.

89

Implementing Strategies for Drying and Pressing Wood Without Emissions Controls  

Microsoft Academic Search

Drying and pressing wood for the manufacture of lumber, particleboard, oriented strand board (OSB), veneer and medium density fiberboard (MDF) release volatile organic compounds (VOCs) into the atmosphere. These emissions require control equipment that are capital-intensive and consume significant quantities of natural gas and electricity. The objective of our work was to understand the mechanisms through which volatile organic compounds

Sujit Banerjee; Terrance Conners

2007-01-01

90

28 CFR 540.64 - Press pools.  

Code of Federal Regulations, 2013 CFR

...Media § 540.64 Press pools. (a) The Warden may establish a press pool whenever he or...that warrants limitations. (b) Whenever the Warden establishes a press pool, the Warden shall notify all news media...

2013-07-01

91

APS undergraduate brainstorming summit report  

NSDL National Science Digital Library

IN 2004, the Education Committee was charged with seeking additional strategies to increase the exposure of undergraduate students to physiology studies and careers. Following a reaffirmation of this charge in the 2006 strategic plan, the American Physiological Society (APS) hosted an undergraduate brainstorming summit in late September of 2006.

PhD Robert G. Carroll (East Carolina State University Department of Physiology); PhD Marsha L Matyas (American Physiological Society Education); Van Doze (University of North Dakota School of Medicine and Health Sciences Pharmacology, Physiology, and Therapeutics); PhD Richard Faircloth (Anne Arundel Community College Dept. of Biology); Patricia Finkenstadt (Phoenix College); PhD Barbara E. Goodman (University of South Dakota School of Medicine Division of Basic Biomedical Sciences)

2007-12-09

92

Impacts of Information Subsidies and Community Structure on Local Press Coverage of Environmental Contamination.  

ERIC Educational Resources Information Center

Finds that a press kit sent by an environmental group to midwestern newspapers influenced them to delegate local staff to cover the story. Indicates that the press's function to report or raise issues concerning industrial toxic releases and related health risks is tempered by community structure and particularly by community reliance on…

Griffin, Robert J.; Dunwoody, Sharon

1995-01-01

93

Censorship of the Collegiate Presses.  

ERIC Educational Resources Information Center

Enumerates determinations of the American judicial system that protect the First Amendment rights of college journalists. Reviews discussions of those determinations. Discusses recent cases of imposed collegiate press censorship. Concludes that students continue to be silenced today. (TB)

Kasior, Serjit; Darrah, Ed

1996-01-01

94

Implementing Strategies for Drying and Pressing Wood Without Emissions Controls. Final Report.  

National Technical Information Service (NTIS)

Drying and pressing wood for the manufacture of lumber, particleboard, oriented strand board (OSB), veneer and medium density fiberboard (MDF) release volatile organic compounds (VOCs) into the atmosphere. These emissions require control equipment that ar...

S. Banerjee T. E. Cornners

2007-01-01

95

The AP-2 family of transcription factors  

PubMed Central

The AP-2 family of transcription factors consists of five different proteins in humans and mice: AP-2?, AP-2?, AP-2?, AP-2? and AP-2?. Frogs and fish have known orthologs of some but not all of these proteins, and homologs of the family are also found in protochordates, insects and nematodes. The proteins have a characteristic helix-span-helix motif at the carboxyl terminus, which, together with a central basic region, mediates dimerization and DNA binding. The amino terminus contains the transactivation domain. AP-2 proteins are first expressed in primitive ectoderm of invertebrates and vertebrates; in vertebrates, they are also expressed in the emerging neural-crest cells, and AP-2?-/- animals have impairments in neural-crest-derived facial structures. AP-2? is indispensable for kidney development and AP-2? is necessary for the formation of trophectoderm cells shortly after implantation; AP-2? and AP-2? levels are elevated in human mammary carcinoma and seminoma. The general functions of the family appear to be the cell-type-specific stimulation of proliferation and the suppression of terminal differentiation during embryonic development.

Eckert, Dawid; Buhl, Sandra; Weber, Susanne; Jager, Richard; Schorle, Hubert

2005-01-01

96

Detecting protected layer-3 rogue APs  

Microsoft Academic Search

Unauthorized rogue access points (APs), such as those brought into a corporate campus by employees, pose a security threat as they may be poorly managed or insufficiently secured. Any attacker in the vicinity can easily get onto the internal network through a rogue AP, bypassing all perimeter security measures. Existing detection solutions work well for detecting layer-2 rogue APs. It

Hongda Yin; Guanling Chen; Jie Wang

2007-01-01

97

Sherwood/APS 2006 Conference  

SciTech Connect

The International Sherwood Theory Meeting is a yearly meeting that focuses on the theory of magnetically confined fusion plasmas. There are many topics of common interest in fusion plasma systems and space and astrophysical plasmas. These common topics include such key topics as magnetic reconnection, the dynamo, turbulence and transport and particle heating and acceleration. One of the major participants of the April APS meeting is the APS Division of Astrophysics (DAP). The goal of having the Sherwood Meeting jointly with the April meeting was to promote discussion of topics of common interest in fusion and space and astrophysics. Scientists from the DAP, the Division of Plasma Physics (DPP), the Topical Group on Plasma Astrophysics (GPAP) and Sherwood worked together closely to produce a joint program that addressed areas of common interest. Four sessions of invited talks were sponsored jointly by the DAP, DPP and GPAP on laboratory experiments related to astrophysics. Plasma scientists working in theory and computation play a key role in connecting these laboratory experiments to the very disparate conditions found in fusion and astrophysical systems. Thus, the attendees of the Sherwood Theory meeting were critical to facilitating this effort at cross-disciplinary communication. Noteworthy were the selection of two of the prestigious plenary talks at the joint meeting on plasma topics - one related to the gyrokinetic modeling of turbulence and the other related to the structure of collisionless shocks. It is rare to see even a single plenary talk on plasma physics at the APS April Meeting. There were additional costs associated with hosting a joint meeting. The Office of Fusion Energy Sciences contributed $3000 in partial support of this meeting. This funding covered part of the costs of the poster boards and A. V. equipment that was used in the presentation of nearly 200 scientific papers related to magnetically confined fusion plasmas. The APS waived its indirect costs on this funding as part of their effort to support this joint meeting.

James F. Drake

2009-07-28

98

The Melanocortin Agonist AP214 Exerts Anti-Inflammatory and Proresolving Properties  

PubMed Central

Synthetic and natural melanocortin (MC) peptides afford inhibitory properties in inflammation and tissue injury, but characterization of receptor involvement is still elusive. We used the agonist AP214 to test MC-dependent anti-inflammatory effects. In zymosan peritonitis, treatment of mice with AP214 (400 to 800 ?g/kg) inhibited cell infiltration, an effect retained in MC receptor type 1, or MC1, mutant mice but lost in MC3 null mice. In vitro, cytokine release from zymosan-stimulated macrophages was affected by AP214, with approximately 80%, 30%, and 40% reduction in IL-1?, tumor necrosis factor-?, and IL-6, respectively. Inhibition of IL-1? release was retained in MC1 mutant cells but was lost in MC3 null cells. Furthermore, AP214 augmented uptake of zymosan particles and human apoptotic neutrophils by wild-type macrophages: this proresolving property was lost in MC3 null macrophages. AP214 displayed its pro-efferocytotic effect also in vivo. Finally, in a model of inflammatory arthritis, AP214 evoked significant reductions in the clinical score. These results indicate that AP214 elicits anti-inflammatory responses, with a preferential effect on IL-1? release. Furthermore, we describe for the first time a positive modulation of an MC agonist on the process of efferocytosis. In all cases, endogenous MC3 is the receptor that mediates these novel properties of AP214. These findings might clarify the tissue-protective properties of AP214 in clinical settings and may open further development for novel MC agonists.

Montero-Melendez, Trinidad; Patel, Hetal B.; Seed, Michael; Nielsen, S?ren; Jonassen, Thomas E.N.; Perretti, Mauro

2011-01-01

99

Molecular evolution of the AP2 subfamily.  

PubMed

The AP2 (APETALA2)/EREBP (Ethylene Responsive Element Binding Protein) multigene family includes developmentally and physiologically important transcription factors. AP2/EREBP genes are divided into two subfamilies: AP2 genes with two AP2 domains and EREBP genes with a single AP2/ERF (Ethylene Responsive Element Binding Factor) domain. Based on previous phylogenetic analyses, AP2 genes can be divided into two clades, AP2 and ANT groups. To clarify the molecular evolution of the AP2 subfamily, we isolated and sequenced genes with two AP2 domains from three gymnosperms, Cycas revoluta, Ginkgo biloba, and Gnetum parvifolium,as well as from the moss Physcomitrella patens. Expressions of AP2-like genes, including AP2, in Arabidopsis thaliana are regulated by the microRNA miR172. We found that the target site of miR172 is significantly conserved in gymnosperm AP2 homologs, suggesting that regulatory mechanisms of gene expression using microRNA have been conserved over the three hundred million years since the divergence of gymnosperm and flowering plant lineages. We inferred a phylogenetic relationship of these genes with the green alga Chlamydomonas reinhardtii and seed-plant genes available in public DNA databases. The phylogenetic tree showed that the AP2 subfamily diverged into the AP2 and ANT groups before the last common ancestor of land plants and after C. reinhardtii diverged from the land-plant lineage. The tree also indicated that each AP2 and ANT group further diverged into several clades through gene duplications prior to the divergence of gymnosperms and angiosperms. PMID:16388920

Shigyo, Mikao; Hasebe, Mitsuyasu; Ito, Motomi

2006-02-01

100

APS Presents Awards at 2008 ABRCMS Conference  

NSDL National Science Digital Library

This is an article in The Physiologist. APS Presents Awards at Annual ABRCMS Conference APS/NIDDK Minority Travel Fellows Attend the 2008 APS Intersociety Meeting: The Integrative Biology of Exercise Education Special Sessions at Experimental Biology 2009 -------------------------------------------------------------------------------- APS Presents Awards at Annual ABRCMS Conference The APS presented awards to minority undergraduate researchers and was a major conference sponsor at the Annual Biomedical Research Conference for Minority Students (ABRCMS) at DisneyÃÂs Coronado Springs Resort, Lake Buena Vista, FL from November 5-9, 2008.

2009-02-01

101

Lost City News Release  

NSDL National Science Digital Library

This press release from the National Science Foundation provides an overview of the 2003 expedition to the Lost City Hydrothermal Field at the Atlantis Massif. It briefly describes the expedition, features of the Lost City, research results and implications for future discoveries. Photos and images accompany the text.

Affairs, Office O.; Foundation, National S.

102

Enhanced Antimicrobial Activity of AamAP1-Lysine, a Novel Synthetic Peptide Analog Derived from the Scorpion Venom Peptide AamAP1  

PubMed Central

There is great interest in the development of antimicrobial peptides as a potentially novel class of antimicrobial agents. Several structural determinants are responsible for the antimicrobial and cytolytic activity of antimicrobial peptides. In our study, a new synthetic peptide analog, AamAP1-Lysine from the naturally occurring scorpion venom antimicrobial peptide AamAP1, was designed by modifying the parent peptide in order to increase the positive charge and optimize other physico-chemical parameters involved in antimicrobial activity. AamAP1-Lysine displayed potent antibacterial activity against Gram-positive and Gram-negative bacteria. The minimum inhibitory concentration was in the range of 5 to 15 µM with a 10 fold increase in potency over the parent peptide. The hemolytic and antiproliferative activity of AamAP1-Lysine against eukaryotic mammalian cells was minimal at the concentration range needed to inhibit bacterial growth. The antibacterial mechanism analysis indicated that AamAP1-Lysine is probably inducing bacterial cell death through membrane damage and permeabilization determined by the release of ?-galactosidase enzyme from peptide treated E. coli cells. DNA binding studies revealed that AamAP1-Lysine caused complete retardation of DNA migration and could display intracellular activities in addition to the membrane permeabilization mode of action reported earlier. In conclusion, AamAP1-Lysine could prove to be a potential candidate for antimicrobial drug development in future studies.

Almaaytah, Ammar; Tarazi, Shadi; Abu-Alhaijaa, Ahmad; Altall, Yara; Alshar'i, Nizar; Bodoor, Khaldon; Al-Balas, Qosay

2014-01-01

103

Enhanced Antimicrobial Activity of AamAP1-Lysine, a Novel Synthetic Peptide Analog Derived from the Scorpion Venom Peptide AamAP1.  

PubMed

There is great interest in the development of antimicrobial peptides as a potentially novel class of antimicrobial agents. Several structural determinants are responsible for the antimicrobial and cytolytic activity of antimicrobial peptides. In our study, a new synthetic peptide analog, AamAP1-Lysine from the naturally occurring scorpion venom antimicrobial peptide AamAP1, was designed by modifying the parent peptide in order to increase the positive charge and optimize other physico-chemical parameters involved in antimicrobial activity. AamAP1-Lysine displayed potent antibacterial activity against Gram-positive and Gram-negative bacteria. The minimum inhibitory concentration was in the range of 5 to 15 µM with a 10 fold increase in potency over the parent peptide. The hemolytic and antiproliferative activity of AamAP1-Lysine against eukaryotic mammalian cells was minimal at the concentration range needed to inhibit bacterial growth. The antibacterial mechanism analysis indicated that AamAP1-Lysine is probably inducing bacterial cell death through membrane damage and permeabilization determined by the release of ?-galactosidase enzyme from peptide treated E. coli cells. DNA binding studies revealed that AamAP1-Lysine caused complete retardation of DNA migration and could display intracellular activities in addition to the membrane permeabilization mode of action reported earlier. In conclusion, AamAP1-Lysine could prove to be a potential candidate for antimicrobial drug development in future studies. PMID:24776889

Almaaytah, Ammar; Tarazi, Shadi; Abu-Alhaijaa, Ahmad; Altall, Yara; Alshar'i, Nizar; Bodoor, Khaldon; Al-Balas, Qosay

2014-01-01

104

AP reclamation and reuse in RSRM propellant  

NASA Technical Reports Server (NTRS)

A solid propellant ingredient reclamation pilot plant has been evaluated at the Strategic Operations of Thiokol Corporation, located in Brigham City, Utah. The plant produces AP wet cake (95 percent AP, 5 percent water) for recycling at AP vendors. AP has been obtained from two standard propellant binder systems (PBAN and HTPB). Analytical work conducted at Thiokol indicates that the vendor-recrystallized AP meets Space Shuttle propellant specification requirements. Thiokol has processed 1-, 5-, and 600-gallon propellant mixes with the recrystallized AP. Processing, cast, cure, ballistic, mechanical, and safety properties have been evaluated. Phillips Laboratory static-test-fired 70-pound and 800-pound BATES motors. The data indicate that propellant processed with reclaimed AP has nominal properties.

Miks, Kathryn F.; Harris, Stacey A.

1995-01-01

105

Apollo 13 Facts: Press Conference  

NASA Technical Reports Server (NTRS)

Flight Director Gene Krantz gives an overview of the Apollo 13 mission as corrections are made in the power down checklist, passive thermal control, and orbital burns after the spacecraft runs into problems. He then answers questions from the press with the help of Tony England, Bill Peters, and Dick Thorson. Footage then shows newspaper headlines 'We're Not Concerned' and 'Getting Ready to Land' as people watch televisions to see if the astronauts landed safely. The press conference section of this video has sound, the headlines section does not.

2001-01-01

106

Dynamics of intracellular clathrin/AP1- and clathrin/AP3-containing carriers.  

PubMed

Clathrin/AP1- and clathrin/AP3-coated vesicular carriers originate from endosomes and the trans-Golgi network. Here, we report the real-time visualization of these structures in living cells reliably tracked by rapid, three-dimensional imaging with the use of a spinning-disk confocal microscope. We imaged relatively sparse, diffraction-limited, fluorescent objects containing chimeric fluorescent protein (clathrin light chain, ? adaptor subunits, or dynamin2) with a spatial precision of up to ~30 nm and a temporal resolution of ~1 s. The dynamic characteristics of the intracellular clathrin/AP1 and clathrin/AP3 carriers are similar to those of endocytic clathrin/AP2 pits and vesicles; the clathrin/AP1 coats are, on average, slightly shorter-lived than their AP2 and AP3 counterparts. We confirmed that although dynamin2 is recruited as a burst to clathrin/AP2 pits immediately before their budding from the plasma membrane, we found no evidence supporting a similar association of dynamin2 with clathrin/AP1 or clathrin/AP3 carriers at any stage during their lifetime. We found no effects of chemical inhibitors of dynamin function or the K44A dominant-negative mutant of dynamin on AP1 and AP3 dynamics. This observation suggests that an alternative budding mechanism, yet to be discovered, is responsible for the scission step of clathrin/AP1 and clathrin/AP3 carriers. PMID:23103167

Kural, Comert; Tacheva-Grigorova, Silvia K; Boulant, Steeve; Cocucci, Emanuele; Baust, Thorsten; Duarte, Delfim; Kirchhausen, Tom

2012-11-29

107

Gifted Education Press Quarterly, 1995.  

ERIC Educational Resources Information Center

This document consists of the four issues of the newsletter "Gifted Education Press Quarterly" published during 1995. This newsletter addresses issues in the education of gifted children and youth. The major articles are: (1) "Using Today's Technology: Parents Can Help Challenge Gifted Children" (Adrienne O'Neill); (2) "Outcomes-Based Education…

Fisher, Maurice D., Ed.

1995-01-01

108

Hot Isostatic Pressing of Ceramics.  

National Technical Information Service (NTIS)

A mixture containing glass 70 to 95 and BN or B4C powder (0.1-10 microns) 5 to 30 vol. % is used as a secondary pressure medium in hot isostatic pressing of ceramics. Thus, Pyrex beads were mixed with 15% vol. BN powder (average diameter 2 microns), fused...

K. Honma

1985-01-01

109

The Alternative Press in Microform.  

ERIC Educational Resources Information Center

Presented is an analysis of what has been done regarding the preservation of alternative publications in microfilm. The alternative press was defined, for the purposes of this study, as "nonstandard, nonestablishment publications." Two projects undertaken to microfilm such publications, one by the Microphoto Division of Bell and Howell and the…

Tsang, Daniel C.

110

NATIONAL ACADEMY PRESS WEB SITE  

EPA Science Inventory

The National Academy Press is the publisher for the National Academy of Sciences, the National Academy of Engineering, the Institute of Medicine, and the National Research Council. Through this web site, you have access to a virtual treasure trove of books, reports and publicatio...

111

The Changing Press of Paris.  

ERIC Educational Resources Information Center

Traces the history and current status of the Paris press, noting the shrinking of old media fiefdoms and the rise of new ones, the discontinuation of some old leaders but the appearance of new titles, the search for reassertion of influence in the provinces, and the unabating trend toward concentration of ownership. (GW)

Hollstein, Milton

1978-01-01

112

Mars Observer Press Conference JPL  

NASA Astrophysics Data System (ADS)

The Mars Observer mission spacecraft was primarily designed for exploring Mars and the Martian environment. The Mars Observer was launched on September 25, 1992. The spacecraft was lost in the vicinity of Mars on August 21, 1993 when the spacecraft began its maneuvering sequence for Martian orbital insertion. This videotape shows a press briefing, held after the spacecraft had not responded to attempts to communicate with it, to explain to the press the problems and the steps that were being taken to re-establish communication with the spacecraft. The communications had been shutdown prior to the orbital insertion burn to protect the instruments. At the time of the press conference, the communications system was still not operational, and attempts were being made to re-establish communication. Bob McMillan of the Public Affairs Office at JPL gives the initial announcement of the continuing communication problem with the spacecraft. Mr. McMillan introduces William Piotrowski, acting director of solar system exploration, who reiterates that there is indeed no communication with the Observer spacecraft. He is followed by Glenn Cunningham, the Project Manager of the Mars Observer who speaks about the attempts to re-establish contact. Mr. Cunningham is followed by Satenios Dallas, the Mission Manager for the Mars Observer Project, who speaks about the sequence of events leading up to the communication failure, and shows an animated video presenting the orbital insertion maneuvers. The briefing was then opened up for questions from the assembled press, both at JPL and at the other NASA Centers. The questions are about the possible reasons for the communication failure, and the attempts to restore communications with the spacecraft. Dr. Arden L. Albee, chief scientist for the Mars Observer Mission, joins the other panel members to answer questions. At the end of the press briefing the animation of the Mars orbital insertion is shown again.

1993-08-01

113

Multicomponent Implant Releasing Dexamethasone  

NASA Astrophysics Data System (ADS)

Several inflammatory conditions are usually treated with corticosteroids. There are various problems like side effects with traditional applications of steroids, e.g. topical, or systemic routes. Local drug delivery systems have been studied and developed to gain more efficient administration with fewer side effects. Earlier, we reported on developing Dexamethasone (DX) releasing biodegradable fibers. However, their drug release properties were not satisfactory in terms of onset of drug release. Thus, we assessed the development of multicomponent (MC) implant to enhance earlier drug release from such biodegradable fibers. Poly (lactide-co-glycolide) (PLGA) and 2 wt-% and 8 wt-% DX were compounded and extruded with twin-screw extruder to form of fibers. Some of the fibers were sterilized to obtain a change in drug release properties. Four different fiber classes were studied: 2 wt-%, 8 wt-%, sterilized 2 wt-%, and sterilized 8 wt-%. 3×4 different DX-releasing fibers were then heat-pressed to form one multicomponent rod. Half of the rods where sterilized. Drug release was measured from initial fibers and multicomponent rods using a UV/VIS spectrometer. Shear strength and changes in viscosity were also measured. Drug release studies showed that drug release commenced earlier from multicomponent rods than from component fibers. Drug release from multicomponent rods lasted from day 30 to day 70. The release period of sterilized rods extended from day 23 to day 57. When compared to the original component fibers, the drug release from MC rods commenced earlier. The initial shear strength of MC rods was 135 MPa and decreased to 105 MPa during four weeks of immersion in phosphate buffer solution. Accordingly, heat pressing has a positive effect on drug release. After four weeks in hydrolysis, no disintegration was observed.

Nikkola, L.; Vapalahti, K.; Ashammakhi, N.

2008-02-01

114

Tank 241-AP-106, Grab samples, 6AP-98-1, 6AP-98-2 and 6AP-98-3 Analytical results for the final report  

SciTech Connect

This document is the final report for tank 241-AP-106 grab samples. Three grab samples 6AP-98-1, 6AP-98-2 and 6AP-98-3 were taken from riser 1 of tank 241-AP-106 on May 28, 1998 and received by the 222-S Laboratory on May 28, 1998. Analyses were performed in accordance with the ''Compatability Grab Sampling and Analysis Plan'' (TSAP) (Sasaki, 1998) and the ''Data Quality Objectives for Tank Farms Waste Compatability Program (DQO). The analytical results are presented in the data summary report. No notification limits were exceeded. The request for sample analysis received for AP-106 indicated that the samples were polychlorinated biphenyl (PCB) suspects. The results of this analysis indicated that no PCBs were present at the Toxic Substance Control Act (TSCA) regulated limit of 50 ppm. The results and raw data for the PCB analysis are included in this document.

FULLER, R.K.

1999-02-23

115

Hot isostatic pressing of ceramics  

NASA Technical Reports Server (NTRS)

A mixture containing glass 70 to 95 and BN or B4C powder (0.1-10 microns) 5 to 30 vol. % is used as a secondary pressure medium in hot isostatic pressing of ceramics. Thus, Pyrex beads were mixed with 15% vol. BN powder (average diameter 2 microns), fused at 1400 deg for 2 h, cooled, crushed, and put into a graphite crucible. A Si3N4 sintered body was embedded in the powder, heated in vacuum at 1200 deg for 2 h, treated in a hot isostatic press furnace at 1700 deg and 1000 atm. for 1 h, and cooled to give a Si3N4 ceramic. It was easily separated from the crucible.

Honma, K.

1985-01-01

116

ELECTROCHEMICAL CORROSION TESTING OF TANKS 241-AN-102 & 241-AP-107 & 241-AP-108 IN SUPPORT OF ULTRASONIC TESTING  

SciTech Connect

This report presents the results of the corrosion rates that were measured using electrochemical methods for tanks 241-AN-102 (AN-102), 241-AP-107 (AP 107), and 241-AP-108 (AP-108) performed under test plant RPP-PLAN-38215. The steel used as materials of construction for AN and AP tank farms was A537 Class 1. Test coupons of A537 Class 1 carbon steel were used for corrosion testing in the AN-107, AP-107, and AP-108 tank waste. Supernate will be tested from AN-102, AP-107, and Ap-108. Saltcake testing was performed on AP-108 only.

WYRWAS RB; DUNCAN JB

2008-11-20

117

An Efficient, Easily Constructed Cell Homogenizing Press  

PubMed Central

An easily constructed, highly efficient cell homogenizing press is described which should be available to laboratories at moderate cost. The press allows the preparation of homogenates from up to 20 g of packed cell paste in a single batch without danger of damage to the press. Cell breakage and recovery of cell homogenates is accomplished at temperatures which maintain the material in the frozen state. The press may be assembled, disassembled, and cleaned with minimal effort. Images FIG. 2 FIG. 3

Sagers, Richard D.

1962-01-01

118

APS: Lighting up the future  

SciTech Connect

Work on the Advanced Photon Source (APS) at Argonne National Laboratory (ANL) involves the construction and supporting research and development for a national user facility for synchrotron radiation research in the x-ray region. The facility, when operational in 1997, will provide super-intense x-ray beams for many areas of basic research and will serve the entire US x-ray research community of several thousand users. This paper describes the pertinent features of the design, construction and planned operation of the facility; and the impact quality has had in these areas. In addition, the introduction of several quality management techniques such as total quality management, reliability/availability planning, and user interface are discussed concerning their status and success.

Potent, V.J.

1993-09-01

119

The Lily-White University Presses.  

ERIC Educational Resources Information Center

Argues that the university presses are immune from racial change and discusses the problem of using location as an argument for not being able to lure blacks into university publishing. Howard University Press is used to illustrate the problem of budget cutting and the ability to boost black recruitment efforts or establish a united black press…

Shin, Annys

1996-01-01

120

Yale University Press: Disseminating "Lux et Veritas"?  

ERIC Educational Resources Information Center

America's university presses are situated within a network of over one hundred universities, learned societies, and scholarly associations. According to a pamphlet put out by the American Association of University Presses, these presses "make available to the broader public the full range and value of research generated by university faculty."…

Parrott, John B.

2010-01-01

121

DESIGN AND OPERATION OF BELT FILTER PRESSES  

EPA Science Inventory

Because early models of belt filter presses (developed from technology associated with the manufacture of paper) performed poorly, improved design and operation procedures for these presses were studied. Belt filter presses form part of a sludge dewatering system, and in terms of...

122

ASSESSING CHEMICAL RELEASES AND WORKER EXPOSURES FROM A FILTERPRESS  

EPA Science Inventory

Chemical releases and worker exposures associated with the filtration of an industrial wastewater sludge were characterized. The filter was a recessed chamber filter press with an open filtrate discharge system. Chemical releases and worker exposures for a selected chemical were ...

123

Advanced APS Impacts on Vehicle Payloads  

NASA Technical Reports Server (NTRS)

Advanced auxiliary propulsion system (APS) technology has the potential to both, increase the payload capability of earth-to-orbit (ETO) vehicles by reducing APS propellant mass, and simplify ground operations and logistics by reducing the number of fluids on the vehicle and eliminating toxic, corrosive propellants. The impact of integrated cryogenic APS on vehicle payloads is addressed. In this system, launch propulsion system residuals are scavenged from integral launch propulsion tanks for use in the APS. Sufficient propellant is preloaded into the APS to return to earth with margin and noncomplete scavenging assumed. No propellant conditioning is required by the APS, but ambient heat soak is accommodated. High temperature rocket materials enable the use of the unconditioned hydrogen/oxygen in the APS and are estimated to give APS rockets specific impulse of up to about 444 sec. The payload benefits are quantified and compared with an uprated monomethyl hydrazine/nitrogen tetroxide system in a conservative fashion, by assuming a 25.5 percent weight growth for the hydrogen/oxygen system and a 0 percent weight growth for the uprated system. The combination and scavenging and high performance gives payload impacts which are highly mission specific. A payload benefit of 861 kg (1898 lbm) was estimated for a Space Station Freedom rendezvous mission and 2099 kg (4626 lbm) for a sortie mission, with payload impacts varying with the amount of launch propulsion residual propellants. Missions without liquid propellant scavenging were estimated to have payload penalties, however, operational benefits were still possible.

Schneider, Steven J.; Reed, Brian D.

1989-01-01

124

Advanced APS impacts on vehicle payloads  

NASA Technical Reports Server (NTRS)

Advanced auxiliary propulsion system (APS) technology has the potential to both, increase the payload capability of earth-to-orbit (ETO) vehicles by reducing APS propellant mass, and simplify ground operations and logistics by reducing the number of fluids on the vehicle and eliminating toxic, corrosive propellants. The impact of integrated cryogenic APS on vehicle payloads is addressed. In this system, launch propulsion system residuals are scavenged from integral launch propulsion tanks for use in the APS. Sufficient propellant is preloaded into the APS to return to earth with margin and noncomplete scavenging assumed. No propellant conditioning is required by the APS, but ambient heat soak is accommodated. High temperature rocket materials enable the use of the unconditioned hydrogen/oxygen in the APS and are estimated to give APS rockets specific impulse of up to about 444 sec. The payload benefits are quantified and compared with an uprated monomethylhydrazine/nitrogen tetroxide system in a conservative fashion, by assuming a 25.5 percent weight growth for the hydrogen/oxygen system and a 0 percent weight growth for the uprated system. The combination of scavenging and high performance gives payload impacts which are highly mission specific. A payload benefit of 861 kg (1898 lbm) was estimated for a Space Station Freedom rendezvous mission and 2099 kg (4626 lbm) for a sortie mission, with payload impacts varying with the amount of launch propulsion residual propellants. Missions without liquid propellant scavenging were estimated to have payload penalties, however, operational benefits were still possible.

Schneider, Steven J.; Reed, Brian D.

1989-01-01

125

Advanced Placement Program: What's Changing in AP  

NSDL National Science Digital Library

The AP Program has recently redesigned several courses in science, history, and world languages in an effort to stay strongly aligned with college credit policies and to prepare students for future learning and career pursuit. This website focuses on informing AP teachers about what's changing in AP, from course scope to exam preparation. The AP Chemistry revision will take effect in Fall, 2013. The change that will impact physics teachers most directly is the replacement of AP Physics B with two new year-long courses: AP Physics 1 Algebra-Based and AP Physics 2 Algebra-Based (scheduled to be deployed Fall, 2014). The changes to each course were guided by National Research Council and National Science Foundation recommendations, following several years of collaborations among university educators and master AP teachers. Especially noteworthy are the changes that integrate science practice as an essential component of the curriculum, along with statements that pair the essential knowledge (learning goal) to the appropriate science practice and articulate specific performance objectives.

126

APS-DPP Education and Outreach  

NASA Astrophysics Data System (ADS)

Through its membership and their respectful institutions, the APS-DPP continues to be recognized for its education and outreach efforts. Each year starting with the 1988 DPP annual meeting, DPP and the APS Office of Education have jointly sponsored a "Science Teachers' Day." Beginning in 1994, a companion "Plasma Physics Expo" has been held during the same week of the November meeting. Both events continue to receive uniformly enthusiastic responses from teachers and students who participate. These two events are not only supported financially by APS and APS-DPP but also by APS-DPP member contributions and by contributions of the major plasma physics and fusion research institutions. Recently, the DPP Interdivisional and Public Affairs Committee was re-named the DPP Science Education Committee (see DPP Newsletter, Spring 1998) to reflect the importance that the DPP puts on education and outreach. Nevertheless, as Andrew Sessler, APS President, said in the Education Outreach special insert of the January APS News "We have many education and outreach activities in the areas of K -12 education . . . but very few APS members are aware of what we are doing . . . ." This paper is an attempt to communicate to the DPP members who have not participated in DPP's education and outreach activities a summary of what is being accomplished in this area, what is being planned for the future, and how does one participate in these activities.

Correll, Donald

1998-11-01

127

APS News: Limerick Contest Finalists & Winners  

NSDL National Science Digital Library

This article from the March 1997 issue of APS News Online contains the finalists and winners of the first APS Physics Limerick Contest. Twenty-five humorous limericks concentrated on classical and modern physics concepts are provided along with a link to view the remaining submissions.

2006-09-29

128

AP-42 ADDITIONS AND REVISIONS - WILDLAND FIRES  

EPA Science Inventory

This project is aimed at consolidating, selecting, and disseminating the most appropriate data and methods for estimating air emissions from wildfires and prescribed burns. The product will replace a current section of AP-42, but may not take the precise form of an AP-42 secti...

129

The A&P Professor  

NSDL National Science Digital Library

Kevin Patton is the president emeritus of the Human Anatomy and Physiology Society (HAPS) and he is also the brains behind the A&P (Anatomy & Physiology) Professor website. Patton has worked to create this online collection of resources for people teaching human anatomy and physiology, and it's a great counterpart to his blog of the same name. Visitors should start by looking over one of the five tabs at the top of the page, which include Resources, Topics, and How To. The How To contains resources for educators about producing online lectures and various in-class student response systems. The files here are dynamic, and they include interactive sections that make the material quite lively. Moving on, the Resources area includes an online version of an anatomy & physiology textbook created by Patton, along with links to other high-quality resources. Finally, the Lion's Den section of the site contains links to Patton's syllabi, course handouts, and a range of introductory materials for anyone who might be teaching a basic anatomy & physiology course.

Patton, Kevin T.

2012-04-06

130

Number of Schools Offering AP Falls after First Audit of Courses  

ERIC Educational Resources Information Center

This article reports the findings of the first audit of Advanced Placement (AP) courses. One of the more striking effects of the audit, the results of which were released recently by the College Board, was a steep drop in the number of schools offering Advanced Placement courses. After more than 30 years of steady growth, the number of schools…

Cech, Scott J.

2007-01-01

131

Tank 241-AP-107, grab samples, 7AP-99-1, 7AP-99-3 and 7AP-99-4 analytical results for the final report  

SciTech Connect

This document is the format IV, final report for the tank 241-AP-107 (AP-107) grab samples taken in May 1999 to address waste compatibility concerns. Chemical, radiochemical, and physical analyses on the tank AP-107 samples were performed as directed in Compatibility Grab Sampling and Analysis Plan for Fiscal year 1999. Any deviations from the instructions provided in the tank sampling and analysis plan (TSAP) were discussed in this narrative. Interim data were provided earlier to River Protection Project (RPP) personnel, however, the data presented here represent the official results. No notification limits were exceeded.

BELL, K.E.

1999-08-12

132

77 FR 24480 - Application for New Awards; Advanced Placement (AP) Test Fee Program-Reopening the AP Test Fee...  

Federal Register 2010, 2011, 2012, 2013

...Reopening the AP Test Fee Fiscal Year 2012 Competition AGENCY: Office of Elementary and Secondary...reopening the AP Test Fee fiscal year 2012 competition...AP Test Fee fiscal year (FY) 2012 competition (February 15 notice). That...

2012-04-24

133

Slurry-pressing consolidation of silicon nitride  

NASA Technical Reports Server (NTRS)

A baseline slurry-pressing method for a silicon nitride material is developed. The Si3N4 composition contained 5.8 wt percent SiO2 and 6.4 wt percent Y2O3. Slurry-pressing variables included volume percent solids, application of ultrasonic energy, and pH. Twenty vol percent slurry-pressed material was approximately 11 percent stronger than both 30 vol percent slurry-pressed and dry-pressed materials. The Student's t-test showed the difference to be significant at the 99 percent confidence level. Twenty volume percent (300 h) slurry-pressed test bars exhibited strengths as high as 980 MPa. Large, columnar beta-Si3N4 grains caused failure in the highest strength specimens. The improved strength correlated with better structural uniformity as determined by radiography, optical microscopy, and image analysis.

Sanders, William A.; Kiser, James D.; Freedman, Marc R.

1988-01-01

134

Slurry-pressing consolidation of silicon nitride  

NASA Technical Reports Server (NTRS)

A baseline slurry-pressing method for a silicon nitride material is developed. The Si3N4 composition contained 5.8 wt percent SiO2 and 6.4 wt percent Y2O3. Slurry-pressing variables included volume percent solids, application of ultrasonic energy, and pH. Twenty vol percent slurry-pressed material was approximately 11 percent stronger than both 30 vol percent slurry-pressed and dry-pressed materials. The Student's t-test showed the difference to be significant at the 99 percent confidence level. Twenty volume percent (300 h) slurry-pressed test bars exhibited strengths as high as 980 MPa. Large, columnar beta-Si3N4 grains caused failure in the highest strength specimens. The improved strength correlated with better structural uniformity as determined by radiography, optical microscopy, and image analysis.

Sanders, William A.; Kiser, James D.; Freedman, Marc R.

1989-01-01

135

Improving Dryer and Press Efficiencies Through Combustion of Hydrocarbon Emissions  

SciTech Connect

Emission control devices on dryers and presses have been legislated into the industry, and are now an integral part of the drying system. These devices consume large quantities of natural gas and electricity and down-sizing or eliminating them will provide major energy savings. The principal strategy taken here focuses on developing process changes that should minimize (and in some cases eliminate) the need for controls. A second approach is to develop lower-cost control options. It has been shown in laboratory and full-scale work that Hazardous Air Pollutants (HAPs) emerge mainly at the end of the press cycle for particleboard, and, by extension, to other prod-ucts. Hence, only the air associated with this point of the cycle need be captured and treated. A model for estimating terpene emissions in the various zones of veneer dryers has been developed. This should allow the emissions to be concentrated in some zones and minimized in others, so that some of the air could be directly released without controls. Low-cost catalysts have been developed for controlling HAPs from dryers and presses. Catalysts conventionally used for regenerative catalytic oxidizers can be used at much lower temperatures for treating press emissions. Fluidized wood ash is an especially inexpensive mate-rial for efficiently reducing formaldehyde in dryer emissions. A heat transfer model for estimating pinene emissions from hot-pressing strand for the manufacture of flakeboard has been constructed from first principles and validated. The model shows that most of the emissions originate from the 1-mm layer of wood adjoining the platen surface. Hence, a simple control option is to surface a softwood mat with a layer of hardwood prior to pressing. Fines release a disproportionate large quantity of HAPs, and it has been shown both theo-retically and in full-scale work that particles smaller than 400 ���µm are principally responsible. Georgia-Pacific is considering green-screening their furnish at several of their mills in order to remove these particles and reduce their treatment costs.

Sujit Banerjee

2005-10-31

136

NASA/MSFC Large Stretch Press Study  

NASA Technical Reports Server (NTRS)

The purpose of this study was to: A. assess and document the advantages/disadvantages of a government agency investment in a large stretch form press on the order of 5000 tons capacity (per jaw); B. develop a procurement specification for the press; and C. provide trade study data that will permit an optimum site location. Tasks were separated into four major elements: cost study, user survey, site selection, and press design/procurement specification.

Choate, M. W.; Nealson, W. P.; Jay, G. C.; Buss, W. D.

1985-01-01

137

APS Forum on Education Newsletter - Fall 2007  

NSDL National Science Digital Library

The Fall edition of the APS Forum on Education newsletter contains an extensive discussion of teacher preparation resources in ComPADRE, FEd sessions at the 2007 March meeting, and an update of the Gathering Storm.

2008-02-08

138

APS Activities with Other Professional Societies  

NASA Astrophysics Data System (ADS)

In 1981, the APS Council issued a statement that opposed ``equal time'' presentation in public school science classes of creationism and evolution. The statement clarified that ``Scientific inquiry and religious beliefs are two distinct elements of the human experience. Attempts to present them in the same context can only lead to misunderstandings of both.'' The APS Council revisited the issue in 1999 when a school board in Kansas attempted to eliminate the Big Bang, among other issues, from the science curriculum. Since that time, the APS has been more directly involved in confronting efforts that would dilute the teaching of science in public school science classes. This talk will review the APS activities and describe a developing multi-science society activity.

Slakey, Francis

2006-03-01

139

Preliminary analysis of the APS crotch design.  

National Technical Information Service (NTIS)

A preliminary design analysis of the absorber plate of the proposed crotch for the APS bending magnet radiation is presented. Various design aspects including thermal and structural considerations, material selection, geometry, and cooling method are disc...

A. M. Khounsary

1990-01-01

140

APS Council Holds Fall Council Meeting  

NSDL National Science Digital Library

This is an article from The Physiologist. The APS Council held their fall meeting at the Scottsdale Marriott at McDowell Mountains, Scottsdale, AZ, November 8-9, 2007. Council received reports from the Publications, Finance, Membership, Education, and other Committees. APS staff members Marsha Matyas, Robert Price, Alice RaÃÂanan, and Margaret Reich joined the meeting to assist with the committee report presentations.

2008-02-01

141

Near-net-shape forming of alumina powder under hot pressing and hot isostatic pressing  

Microsoft Academic Search

Densification and deformation of alumina powder under hot pressing and hot isostatic pressing were investigated. Finite element calculations were performed by implementing constitutive equations for grain growth, power law creep and diffusional creep in the user defined subroutine CREEP of ABAQUS. An alumina compact of valve head shape was produced under hot pressing and its forming process was predicted by

K. T. Kim; Y. S. Kwon; H. G. Kim

1997-01-01

142

Impact Fragmentation and Ballistics of Pressed Aluminum Powder Projectiles  

NASA Astrophysics Data System (ADS)

The penetration and fragmentation characteristics of spheres made of pressed aluminum powder are studied via normal impact on thin steel plates at 0.6 to 1.8 km/s. Ultra-high speed photography and flash x-rays are used to monitor the formation and evolution of the debris cloud formed by impact. The mass distribution of debris fragments is measured directly via a soft-catch experiment. Experimental results are compared to simple analytic theories of brittle fragmentation and spall. This data aids in understanding the mechanical properties and potential energy release of porous reactive materials.

Thuot, S. C.; Wilkinson, J.; Lee, R. J.; Carney, J. R.; Hooper, J.; Lightstone, J. M.; Jouet, J. R.; Rogerson, J. G.

2009-12-01

143

Elastic properties of hot-isostatically-pressed magnesium diboride  

NASA Astrophysics Data System (ADS)

Magnesium diboride was hot-isostatically pressed using three qualitatively different cycles: dense material cooled under pressure (DMCUP), ``standard'' cycle with pressure and temperature simultaneously reduced, and isothermal pressure release. Elastic properties of dense MgB2 were measured at normal conditions using resonant ultrasound spectroscopy method. The highest values of elastic moduli correspond to the sample processed using DMCUP cycle. The data for fully dense samples are in satisfactory agreement with theoretical predictions based on quantum mechanics calculations. The effect of lower density on elastic constants is consistent with a theoretical approach based on elasticity theory taking into account effect of porosity.

Nesterenko, V. F.; Gu, Y.

2003-06-01

144

Fabrication of lithium ceramics by hot pressing  

SciTech Connect

Controlled density LiA10/sub 2/, Li/sub 2/Zr0/sub 3/, Li/sub 4/SiO/sub 4/ and Li/sub 2/O pellets were fabricated by hot pressing for irradiation testing as candidate tritium breeding materials. Pellet specifications, characterization data, and procedures for hot pressing, pellet grinding and halide removal are discussed.

Wilson, C.N.

1982-03-01

145

Linguistic Cohabitation: Frenglish in the Mauritius Press.  

ERIC Educational Resources Information Center

Discusses the use of Frenglish on the island of Mauritius. An examination of the local press over a nine-month period turned up ten categories of Frenglish. Frenglish in the Mauritian press highlights the uniqueness of local society by linguistically contextualizing broad ranges of social, economic, political, legal, and administrative life.…

Miles, William F. S.

1998-01-01

146

Back to bedlam? Chelmsford and the press.  

PubMed

The Australian press played a vital part in bringing the events at Chelmsford Private Hospital to the attention of the general public, and in pressuring the New South Wales government to institute a Royal Commission into Deep Sleep Therapy. This paper describes the ways in which the press brought Chelmsford events onto the public agenda. It pays particular attention to aspects of the press coverage of the findings of the Royal Commission. The paper identifies the discourses concerning psychiatric care, the doctor-patient relationship and the role of the government in regulating the medical profession which were dominant in press accounts of Chelmsford. It is argued that while pre-existing stereotypes about mad psychiatrists and asylums were used to describe Chelmsford, more confronting ideas concerning the need for medical regulation and patient consumerism received press attention and therefore a public airing. The implications for psychiatric care in Australia are examined. PMID:8481154

Lupton, D

1993-03-01

147

Tank 241-AP-107, grab samples 7AP-97-1, 7AP-97-2 and 7AP-97-3 analytical results for the final report  

SciTech Connect

This document is the final report for tank 241-AP-107 grab samples. Three grab samples were collected from riser 1 on September 11, 1997. Analyses were performed on samples 7AP-97-1, 7AP-97-2 and 7AP-97-3 in accordance with the Compatibility Grab Sampling and Analysis Plan (TSAP) (Sasaki, 1997) and the Data Quality Objectives for Tank Farms Waste Compatibility Program (DQO) (Rev. 1: Fowler, 1995; Rev. 2: Mulkey and Nuier, 1997). The analytical results are presented in the data summary report (Table 1). A notification was made to East Tank Farms Operations concerning low hydroxide in the tank and a hydroxide (caustic) demand analysis was requested. The request for sample analysis (RSA) (Attachment 2) received for AP-107 indicated that the samples were polychlorinated biphenyl (PCB) suspects. Therefore, prior to performing the requested analyses, aliquots were made to perform PCB analysis in accordance with the 222-S Laboratory administrative procedure, LAP-101-100. The results of this analysis indicated that no PCBs were present at 50 ppm and analysis proceeded as non-PCB samples. The results and raw data for the PCB analysis will be included in a revision to this document. The sample breakdown diagrams (Attachment 1) are provided as a cross-reference for relating the tank farm customer identification numbers with the 222-S Laboratory sample numbers and the portion of sample analyzed.

Steen, F.H.

1997-12-22

148

Automated Plasma Spray (APS) process feasibility study  

NASA Technical Reports Server (NTRS)

An automated plasma spray (APS) process was developed to apply two layer (NiCrAlY and ZrO2-12Y2O3) thermal barrier coatings to aircraft and stationary gas turbine engine blade airfoils. The APS process hardware consists of four subsystems: a mechanical positioning subsystem incorporating two interlaced six degree of freedom assemblies (one for coating deposition and one for coating thickness monitoring); a noncoherent optical metrology subsystem (for in process gaging of the coating thickness buildup at specified points on the specimen); a microprocessor based adaptive system controller (to achieve the desired overall thickness profile on the specimen); and commerical plasma spray equipment. Over fifty JT9D first stage aircraft turbine blade specimens, ten W501B utility turbine blade specimens and dozens of cylindrical specimens were coated with the APS process in preliminary checkout and evaluation studies. The best of the preliminary turbine blade specimens achieved an overall coating thickness uniformity of 53 micrometers (2.1 mils), much better than is achievable manually. Comparative evaluations of coating thickness uniformity for manually sprayed and APS coated specimens were performed. One of the preliminary turbine blade evaluation specimens was subjected to a torch test and metallographic evaluation. Some cylindrical specimens coated with the APS process survived up to 2000 cycles in subsequent burner rig testing.

Fetheroff, C. W.; Derkacs, T.; Matay, I. M.

1981-01-01

149

Mariner Mars 1971: Press kit  

NASA Technical Reports Server (NTRS)

The news release describes the 1971 launches of Mariner 8 and 9 which were to be the first attempt by NASA to orbit another planet, Mars. Described are: (1) mission capsule; (2) planetary missions; (3) aiming zones; (4) the spacecraft; (5) scientific experiments to be performed; (6) Atlas Centaur launch vehicle; (7) launch operations; (8) tracking and data system and mission operations; and (9) Mariner Mars 71 team and subcontractors.

Mittauer, R. T.

1971-01-01

150

A phenylalanine zipper mediates APS dimerization.  

PubMed

The APS, SH2-B and LNK proteins are adapters that activate and modulate receptor tyrosine kinase and JAK/STAT signaling. We now show that a conserved N-terminal domain mediates APS homodimerization. We determined the crystal structure of the dimerization domain at a resolution of 1.7 A using bromide ion MAD phasing. Each molecule contributes two helices to a compact four-helix bundle having a bisecting-U topology. Its most conspicuous feature is a stack of interdigitated phenylalanine side chains at the domain core. These residues create a new motif we refer to as a 'phenylalanine zipper,' which is critical to dimerization. A newly developed bridging yeast tri-hybrid assay showed that APS dimerizes JAK2, insulin receptor and IGF1 receptor kinases using its SH2 and dimerization domains. Dimerization via the phenylalanine zipper domain provides a mechanism for activating and modulating tyrosine kinase activity even in the absence of extracellular ligands. PMID:15378031

Dhe-Paganon, Sirano; Werner, Eric D; Nishi, Masahiro; Hansen, Lone; Chi, Young-In; Shoelson, Steven E

2004-10-01

151

Mechanical Properties from PBX 9501 Pressing Study  

NASA Astrophysics Data System (ADS)

A PBX 9501 pressing study was conducted by researchers in ESA-WMM, LANL, to identify the hydrostatic pressing parameters most important in fabricating high-density parts with uniform density. In this study, 31 charges were pressed using a full permutation of six pressing parameters. Five charges from the set of 31 were selected for an evaluation of their mechanical properties, specifically uniaxial compression and tension. Charges were selected to 1) span the density range of the study, and 2) allow two direct comparisons of pressing parameters independent of bulk density (density has a well-established affect on some material properties). Three PBX 9501 charges pressed isostatically at Pantex Plant in Amarillo, TX were also included in the study. The tensile properties of the 8 charges varied significantly. Careful evaluation of the results suggests that an increase in pressing temperature may correlate with an increase in tensile stress (strength) and a decrease in strain (ductility). Trends in compression exist but are less pronounced. In an effort to explore the relationship between pressing temperature and tensile strength, four sheets of Estane polymer (a component of the PBX 9501 binder) were compression molded at 70, 90, 110 and 130°C. The tensile strength of Estane was observed to increase by a factor of nearly 20 when the molding temperature was increased from 70 to 90°C (strength increase was negligible beyond 90°C). We present an outline of ongoing work that will irrefutably quantify the mechanical property affects of both pressing temperature and dwell time on PBX 9501.(LA-UR 03-4842).

Graff Thompson, Darla; Wright, Walter J.

2004-07-01

152

The Clathrin Adaptor AP-1A Mediates Basolateral Polarity  

PubMed Central

Summary Clathrin and the epithelial-specific clathrin adaptor AP-1B mediate basolateral trafficking in epithelia. However, several epithelia lack AP-1B and mice knocked-out for AP-1B are viable, suggesting the existence of additional mechanisms that control basolateral polarity. Here, we demonstrate a distinct role of the ubiquitous clathrin adaptor AP-1A in basolateral protein sorting. Knock-down of AP-1A causes missorting of basolateral proteins in MDCK cells but only after knock-down of AP-1B, suggesting that AP-1B can compensate for lack of AP-1A. AP-1A localizes predominantly to the TGN and its knock-down promotes spillover of basolateral proteins into common recycling endosomes, the site of function of AP-1B, suggesting complementary roles of both adaptors in basolateral sorting. Yeast two-hybrid assays detect interactions between the basolateral signal of TfR and the medium subunits of both AP-1A and AP-1B. The basolateral sorting function of AP-1A reported here establishes AP-1 as a major regulator of epithelial polarity.

Gravotta, Diego; Carvajal-Gonzalez, Jose Maria; Mattera, Rafael; Deborde, Sylvie; Banfelder, Jason R.; Bonifacino, Juan S.; Rodriguez-Boulan, Enrique

2013-01-01

153

Hot Isostatic Pressing of Ceramic Powder Compacts.  

National Technical Information Service (NTIS)

The densification of aluminum oxide in hot isostatic pressing has been studied in detail. Methods for calculating maps of densification rate as function of temperature and applied pressure have been developed. A new mechanism, interface-reaction-controlle...

J. K. McCoy A. J. Markworth

1986-01-01

154

Hot Isostatic Pressing of Ceramic Powder Compacts.  

National Technical Information Service (NTIS)

The effect of temperature, pressure and time on the rate of densification of submicron alumina powder during hot isostatic pressing has been determined using a dilatometer to continuously monitor volumetric changes. A Fortran computer program is used to m...

J. K. McCoy R. R. Wills

1984-01-01

155

An Introduction to Bibliographical Press Work.  

National Technical Information Service (NTIS)

This guide to the literature of bibliographical press work is comprised of brief introductory notes on the field and this bibliography, followed by citations listed in seven categories: (1) book production, (2) handmade paper, (3) printer's ink, (4) type ...

J. V. Richardson

1978-01-01

156

Gas-driven filter pressing in magmas  

USGS Publications Warehouse

Most silicic and some mafic magmas expand via second boiling if they crystallize at depths of about 10 km or less. The buildup of gas pressure due to second boiling can be relieved by expulsion of melt out of the region of crystallization, and this process of gas-driven filter pressing assists the crystallization differentiation of magmas. For gas-driven filter pressing to be effective, the region of crystallization must inflate slowly relative to buildup of pressure and expulsion of melt These conditions are satisfied in undercooled magmatic inclusions and in thin sheets of primitive magma underplating cooler magma reservoirs. Gas-driven filter pressing thereby adds fractionated melt to magma bodies. Gas-driven filter pressing is probably the dominant process by which highly evolved melts segregate from crystal mush to form aplitic dikes in granitic plutons; this process could also account for the production of voluminous, crystal-poor rhyolites.

Sisson, T. W.; Bacon, C. R.

1999-01-01

157

Consolidation of Thermites by Pressing and Sintering.  

National Technical Information Service (NTIS)

Consolidated thermites can be used as chemical heat sources. Pressing and sintering, a power metallurgy technique, has been developed to consolidate thermite parts with uniform density, composition, and calorific output. These materials are safe to handle...

L. D. Abney M. D. Kelly

1984-01-01

158

Consolidation of thermites by pressing and sintering  

SciTech Connect

Consolidated thermites can be used as chemical heat sources. Pressing and sintering, a power metallurgy technique, has been developed to consolidate thermite parts with uniform density, composition, and calorific output. These materials are safe to handle, machineable, and generate minimum gas pressure upon reaction. This technique consists of die pressing various compositions of blended thermite powders, then isostatic pressing the parts before sintering to ensure the uniform density of the thermite composites. Parts sintered at various temperatures were examined metallographically for compositional uniformity and to determine whether diffusion between the powders had occurred. Flexure and tensile strength values were obtained to determine the temperature range required to produce strong parts. The coordination of metallography and strength values for various compositions and sintering temperature resulted in data that were used to optimize the fabrication process. Consolidation of thermite by pressing and sintering was found to be a valid process for producing uniform, dense, strong thermite parts.

Kelly, M.D.; Abney, L.D.

1984-01-01

159

Meteorologia na Imprensa (Meteorology in the Press).  

National Technical Information Service (NTIS)

Analysis of press coverage in the area of meteorology in the period 1983 to 1988 involves eight means of communication. The topic is subdivided into eight themes, not considering daily weather forecasts and non-scientific materials. Statistics, results, a...

B. C. P. Dornelles

1988-01-01

160

Apollo 13 Facts [Post Flight Press Conference  

NASA Technical Reports Server (NTRS)

The Apollo 13 astronauts, James Lovell, Jr., John Swigert, Jr., and Fred Haise, Jr., are seen during this post flight press conference. They describe their mission and answer questions from the audience.

2001-01-01

161

College Board Readies Plans for AP Audits  

ERIC Educational Resources Information Center

This article describes the educators mixed reviews regarding the audit system planned by the College Board to scrutinize high school Advanced Placement courses. Teachers of AP courses are required to submit materials to the College Board proving that their course syllabuses meet the program's curricular requirements. It is the most extensive…

Klein, Alyson

2006-01-01

162

The AP Descriptive Chemistry Question: Student Errors  

ERIC Educational Resources Information Center

For over a decade, the authors have been involved in a design theory experiment providing software for high school students preparing for the descriptive question on the Advanced Placement (AP) chemistry examination. Since 1997, the software has been available as a Web site offering repeatable practice. This study describes a 4-year project during…

Crippen, Kent; Brooks, David W.

2005-01-01

163

Creation of post AP chemistry class  

NASA Astrophysics Data System (ADS)

The creation of a Post AP Chemistry Class to be taught at the high school level for grade 12 students is discussed. The class is to be taught under the supervision of the University of Texas Pan American professors and taught by an MS Chemistry teacher, in order to better transition students into upper level chemistry courses beyond Chemistry 1401 and 1402.

Medrano, Julian

164

Tank 241-AP-107 tank characterization plan  

SciTech Connect

This document is a plan which serves as the contractual agreement between the Characterization Program, Sampling Operations, WHC 222-S Laboratory, and PNL 325 Analytical Chemistry Laboratory. The scope of this plan is to provide guidance for the sampling and analysis of samples from tank 241-AP-107.

Schreiber, R.D.

1994-12-06

165

APS Presents Awards at 2006 ABRCMS Conference  

NSDL National Science Digital Library

An article from The Physiologist. The APS presented awards to minority undergraduate researchers and was a major conference sponsor at the Annual Biomedical Research Conference for Minority Students (ABRCMS) at the Anaheim Convention Center and Anaheim Marriott hotel in Anaheim, CA from November 8-11, 2006.

APS Education Office (American Physiological Society Education Office)

2007-04-01

166

Gapminder: An AP Human Geography Lab Assignment  

ERIC Educational Resources Information Center

This lesson is designed as a lab assignment for Advanced Placement (AP) Human Geography students wherein they use the popular Gapminder web site to compare levels of development in countries from different world regions. For this lesson, it is important for the teacher to practice with Gapminder before giving the assignment to students. (Contains…

Keller, Kenneth H.

2012-01-01

167

AP Biology Investigation #6: Cellular Respiration  

NSDL National Science Digital Library

This is the Advanced Placement Investigation into cellular respiration (#6). The investigation was developed by the College Board for use in AP Biology classes. Students begin by investigating the question, What factors affect the rate of cellular respiration in multicellular organisms? Later, students investigate one of their own questions that arose during the first investigation. Wisconsin Fast Plants are used as a model organism.

Approach, Ap B.

168

Building a Robust A-P Axis  

PubMed Central

Since the last common ancestor of Metazoa, animals have evolved complex body plans with specialized cells and spatial organization of tissues and organs. Arguably, one of the most significant innovations during animal evolutionary history was the establishment of a bilateral plane of symmetry on which morphological features (e.g. tissues, organs, appendages, skeleton) could be given specific coordinates within the animal along the anterior-posterior (A-P) and dorsal-ventral (D-V) axes. Hox genes are a known group of eumetazoan transcription factors central to regulating A-P patterning, but less well known and under current investigation is the broader regulatory landscape incorporating these genes, including microRNA (miRNA) regulation. The degree to which evolutionarily conserved targeting of Hox genes by Hox-embedded miRNAs contributes directly to A-P patterning is under investigation, yielding contrasting information dependent on the organism and miRNA of interest. The widespread A-P patterning defects observed in recent miR-196 loss-of-function studies solidifies the importance of miRNA regulation in Hox genetic hierarchies, and elucidating the developmental and evolutionary importance of all Hox-embedded miRNAs remains a challenge for the future.

Heimberg, Alysha; McGlinn, Edwina

2012-01-01

169

The type Ic hypernova SN 2002ap  

Microsoft Academic Search

We investigate the properties of the Type Ic supernova (SN) 2002ap through models of its spectral evolution and light curve (LC). Its spectra are similar to those of the “hypernova” SN 1997ef, showing unusually broad O i, Ca ii, Si ii and Fe ii P Cygni lines. However, its kinetiv energy [? (4 – 10) × 1051 ergs], and the

J. Deng; P. A. Mazzali; K. Maeda; K. Nomoto; H. Umeda; K. Hatano; K. Iwamoto; Y. Yoshii; Y. Kobayashi; T. Minezaki; M. Doi; K. Enya; H. Tomita; S. J. Smartt; K. Kinugasa; H. Kawakita; K. Ayani; T. Kawabata; H. Yamaoka; Y. L. Qiu; K. Motohara; C. L. Gerardy; R. Fesen; K. S. Kawabata; M. Iye; N. Kashikawa; G. Kosugi; Y. Ohyama; M. Takada-Hidai; G. Zhao; R. Chornock; A. V. Filippenko; S. Benetti; M. Turatto

2003-01-01

170

Tank 241-AP-106, grab samples, 6AP-96-1 through 6AP-96-3 analytical results for the final report  

SciTech Connect

This document is the final report for tank 241-AP-106 grab samples. This document presents the analytical results for three samples (6AP-96-1, 6AP-96-2 and 6AP-96-3) taken from riser 1 @ 150{degrees} of tank 241-AP-1 06 on September 12, 1996. Analyses were performed in accordance with the Compatibility Grab Sampling and Analysis Plan (TSAP) (Sasaki, 1996) and the Data Quality Objectives for Tank Farms Waste Compatibility Program (DQO) (Fowler, 1995).

Esch, R.A., Westinghouse Hanford

1996-12-11

171

An in vitro investigation of the suitability of press-coated tablets with hydroxypropylmethylcellulose acetate succinate (HPMCAS) and hydrophobic additives in the outer shell for colon targeting  

Microsoft Academic Search

To develop a new colon targeting formulation, which can suppress drug release completely during 12 h in the stomach and release the drug rapidly after a lag time of 3±1 h in the small intestine, the use of press-coated tablets with hydroxypropylmethylcellulose acetate succinate (HPMCAS) in the outer shell was investigated. The release of diltiazem hydrochloride (DIL) as a model

Eiji Fukui; Nobuteru Miyamura; Masao Kobayashi

2001-01-01

172

AP-42 ADDITIONS AND REVISIONS - RESIDENTIAL WOOD COMBUSTION  

EPA Science Inventory

This project develops emission factors, etc., for residential fireplaces and woodstoves which are incorporated into AP-42. AP42 is a massive collection of material which describes processes which generate air emissions and presents emission factors and control effectiveness infor...

173

Promoter Specificity and Biological Activity of Tethered AP1 Dimers  

Microsoft Academic Search

Activator protein 1 (AP-1) is a group of dimeric transcription factors composed of Jun, Fos, and ATF family proteins. Both gain- and loss-of-function studies have revealed specific roles for individual AP-1 components in cell proliferation, differentiation, apoptosis, and other biological processes. However, little is known about the functions of specific AP-1 dimers. To test the importance of AP-1 composition in

Latifa Bakiri; Koichi Matsuo; Marta Wisniewska; Erwin F. Wagner; Moshe Yaniv

2002-01-01

174

Graphic Arts: Book Three. The Press and Related Processes.  

ERIC Educational Resources Information Center

The third of a three-volume set of instructional materials for a graphic arts course, this manual consists of nine instructional units dealing with presses and related processes. Covered in the units are basic press fundamentals, offset press systems, offset press operating procedures, offset inks and dampening chemistry, preventive maintenance…

Farajollahi, Karim; And Others

175

Activation of AP-1 Contributes to the ?-Adrenoceptor-Mediated Myocardial Induction of Interleukin-6  

PubMed Central

The induction of proinflammatory cytokines in stressed myocardium is considered an innate immune response, but the role of ?-adrenergic signaling in this proinflammatory response and the mechanisms of cardioprotection by ?-blockers are not fully understood. In the present study, we analyzed interleukin-6 (IL-6) formation and promoter activation in ?-adrenoceptor-stimulated neonatal rat cardiomyocytes, in transgenic mice with cardiac overexpression of ?1-adrenoceptors, and in failing human myocardium. IL-6 formation and release in cultured cardiomyocytes under ?-adrenoceptor stimulation requires the activation of activating protein-1 (AP-1) binding sites and of cAMP response elements (CRE) in the IL-6 promoter, but this release (140 ± 6 pg/mL medium under 10?6 M isoproterenol vs. 81 ± 3 pg/mL unstimulated, P < 0.05) is moderate compared with that under inflammatory stimulation (855 ± 44 pg/mL, endotoxin 0.1?g/mL). Similarly, IL-6 is induced together with CRE- and AP-1 activation in the left ventricle (LV) of ?1-transgenic mice before the onset of failure. However, we observed IL-6 induction with activation of NF-?B in addition to CRE and AP-1 in ?1-transgenic mice at the age of 22 weeks and in explanted human LV after full development of failure. Treatment with ?-blockers lowered myocardial IL-6 as well as AP-1, NF-?B, and CRE activation. Therefore, the activation of AP-1 and CRE is part of ?-adrenergic signal transduction for IL-6 induction in nonfailing and failing cardiomyocytes, whereas NF-?B activation contributes only in overloaded failing myocardium.

Rohrbach, Susanne; Engelhardt, Stefan; Lohse, Martin J; Werdan, Karl; Holtz, Juergen; Muller-Werdan, Ursula

2007-01-01

176

The IBM\\/APS Research Internship for Undergraduate Women  

Microsoft Academic Search

The IBM\\/APS Research Internship for Undergraduate Women has been recently adopted as an official program by the APS and the Committee on the Status of Women in Physics. We provide a history of the program, from its start at IBM's Almaden Research Center, through its adoption as an APS program, and its extension to all three IBM Research sites across

Barbara Jones

2001-01-01

177

The Association of American University Presses  

NSDL National Science Digital Library

University-sponsored presses are almost as old as the very enterprise of higher education itself, as their origins can be traced back to the publication of a commentary on the Apostle's Creed at Oxford in 1478. The Association of American University Presses (AAUP) was formed in 1946, and its website offers information that is both specific to the enterprise of scholarly publications and to the general book-loving public. Perhaps most visitors will want to start at the site's "Books for Understanding" feature. Here they will find works published by member university presses that deal with contemporary themes, including civil liberties and terrorism. Another fine resource is the 2005 University Press Books Selected for Public and Secondary Schools Libraries online bibliography. Here visitors will find a list of high-quality titles (organized around the Dewey Decimal system) that will be of interest to readers and librarians. Finally, visitors can also visit the News Desk area to learn about the role university presses play in society and view a list of awards won by AAUP member publishers.

178

The APS Archive of Teaching Resources  

NSDL National Science Digital Library

The American Physiological Society (APS) Archive of Teaching Resources is a digital library of peer-reviewed science teaching resources that contains over 2,200 lesson plans, teaching journal articles, and audiovisual materials. A range of learned societies contribute materials to the archive, including the APS itself and the International Union of Physiological Societies. On the homepage, visitors can click on the Featured area for a nice introduction to some of the most popular materials on the site. Here they can look over the Top 100 resources for use with K-12 students, undergrads, graduate students, and those in continuing education. Moving along, the Research Bytes area contains links to recent news items that cover everything from brain fatigue to exercise strategies that successfully combat Type 2 diabetes. Visitors are encouraged to sign up for their own account on the site, which will allow them to save and categorize resources for their own use.

2012-02-10

179

An activist press: The farm press's coverage of the animal rights movement  

Microsoft Academic Search

The animal rights movement is a serious challenge to current agricultural practices. Agriculture's response, in part, depends on how successfully it can mobilize its natural constituency, farmers. However, theories of the mainstream press suggest that the mainstream press generally covers events, rarely reports or adopts the perspective of alternative movements, rarely includes mobilizing information, and suggests that routine social structures

Ann Reisner

1992-01-01

180

Beryllium window for an APS diagnostics beamline  

SciTech Connect

A beryllium (Be) window for an Advanced Photon Source (APS) diagnostics beamline has been designed and built. The window, which has a double concave axisymmetrical profile with a thickness of 0.5 mm at the center, receives 160 W/mm{sup 2} (7 GeV/100 mA stored beam) from an undulator beam. The window design as well as thermal and thermomechanical analyses, including thermal buckling of the Be window, are presented.

Sheng, I.C.; Yang, B.X.; Sharma, Y.S.

1997-09-01

181

APS Museum "Dialogues with Darwin" Online Exhibition  

NSDL National Science Digital Library

The American Philosophical Society (APS) Museum's "Dialogues with Darwin" exhibition tells the story of Charles Darwinâs theory of evolution and considers the debates about evolution that came both before and after him. The online gallery features all objects, label texts, and wall texts on view in the actual exhibition. The site includes a link to an Educator's Guide which can be downloaded as a pdf file.

American Philosophical Society & Philadelphia Area Center for History of Science

182

Final report for tank 241-AP-108, grab samples 8AP-96-1, 8AP-96-2 and 8AP-96-FB  

SciTech Connect

This document is the final report deliverable for the tank 241-AP-108 grab samples. The samples were subsampled and analyzed in accordance with the TSAP. Included in this report are the results for the Waste Compatibility analyses, with the exception of DSC and thermogravimetric analysis (TGA) results which were presented in the 45 Day report (Part 2 of this document). The raw data for all analyses, with the exception of DSC and TGA, are also included in this report.

Esch, R.A.

1996-04-19

183

The Type Ic Hypernova SN 2002ap  

Microsoft Academic Search

Photometric and spectroscopic data of the energetic Type Ic supernova (SN) 2002ap are presented, and the properties of the SN are investigated through models of its spectral evolution and its light curve. The SN is spectroscopically similar to the ``hypernova'' SN 1997ef. However, its kinetic energy [~(4-10)×1051 ergs] and the mass ejected (2.5-5 Msolar) are smaller, resulting in a faster

P. A. Mazzali; J. Deng; K. Maeda; K. Nomoto; H. Umeda; K. Hatano; K. Iwamoto; Y. Yoshii; Y. Kobayashi; T. Minezaki; M. Doi; K. Enya; H. Tomita; S. J. Smartt; K. Kinugasa; H. Kawakita; K. Ayani; T. Kawabata; H. Yamaoka; Y. L. Qiu; K. Motohara; C. L. Gerardy; R. Fesen; K. S. Kawabata; M. Iye; N. Kashikawa; G. Kosugi; Y. Ohyama; M. Takada-Hidai; G. Zhao; R. Chornock; A. V. Filippenko; S. Benetti; M. Turatto

2002-01-01

184

Press conference held to announce position statement  

NASA Astrophysics Data System (ADS)

AGU held a press conference on Thursday January 28, at the National Press Club in Washington, D.C., to announce that the AGU Council had adopted a position statement on the subject of climate change and greenhouse gases. AGU members Tamara Ledley, senior scientist with TERC in Cambridge, Mass., Eric Sundquist, research geologist with the U.S. Geological Survey in Woods Hole, Mass., and Tim Killeen, professor of atmospheric, oceanic, and space sciences at the University of Michigan were on hand to discuss the statement and answer questions from members of the press. The three scientists drafted the statement and submitted it for Council approval with Dorothy Hall of the NASA/Goddard Space Flight Center in Greenbelt, Md., Stephen Schwartz of Brookhaven National Lab in Upton, N.Y., and Jack Fellows of the University Corporation for Atmospheric Research in Boulder, Colo. The AGU Council approved the statement in December during the 1998 AGU Fall Meeting.

Folger, Peter

185

A comparative study on cell disruption methods for release of aspartase from E. coli K-12.  

PubMed

Applicability of different mechanical cell disruption techniques namely sonication, bead milling and French press for the release of aspartase from E. coli K-12 was compared. Various operating parameters of each technique were optimized to obtain maximum aspartase release. The efficiency of aspartase release and cell disruption by all the methods was also compared under optimal conditions. The maximum release of aspartase (98.22%) and maximum cell breakage (84.25%) was observed using French press, while 92% of aspartase release was obtained by both sonication and bead milling. The order of cell disruption constant (k) for aspartase release by these methods was French press > bead milling > sonication. Disruption of cells using French press also demonstrated maximum protein release (14.12 mg/mL). The crude enzyme preparations can be further used for purification and its applications. PMID:24416937

Singh, R S

2013-11-01

186

Delta II/Geotail Pre-Launch Press Conference  

NASA Technical Reports Server (NTRS)

This video presents a live coverage of a pre-launch press conference on the Delta II/Geotail Mission. George Diller, NASA Public Affairs, presents the panel. The panel consists of James Womack, NASA Launch Manager, Kennedy Space Center; Mario Acuna, Project Scientist, Goddard Space Flight Center; Atsuiro Nishida, Project Manager, ISAS (Institute of Space and Astronautical Science) Tokyo; Michael Calabrese, Program Manager, NASA Headquarters; Kenneth Sizemore, Project Manager, GSFC; Tono Uesugi, Project Manager, ISAS; John Beckham, Delta Launch Manager, GSFC; and Joel Tumbiolo, Launch Weather Officer, CCAFS (Cape Canaveral Air Force Station). Atsuiro Nishida presents the objectives of the Geotail Mission which are: 1) To determine the characteristics of the Geomagnetic Tail; 2) To understand the internal instability that leads to sudden energy releases; 3) To clarify the source of plasma in the tail; and 4) To study the structure of important interfaces such as the Magnetopause. Mario Acuna gives illustrations of the Magnetosphere. James Womack discusses the countdown and status of the mission. Tono Uesugi discusses spacecraft readiness for the July 24, 1992 launch, and Joel Tumbiolo gives the weather forecast for the launch. The press conference concludes with a question and answer period. See NONP-NASA-VT-200078605 for additional questions and footage.

1992-01-01

187

EPICS release 3.11 specific documentation -- EPICS release notes for 3.11  

SciTech Connect

EPICS release 3.11 is now ready for user testing. A person who wants to set up a simplified application environment to boot an IOC and create databases using R3.11 should follow the directions in Appendix B, page 27, of the EPICS Source/Release Control Manual, Sept. 20, 1993. The R3.11 EPICS path at ANL/APS is /net/phebos/epics/R3.11 so the command to get the new release is /net/phebos/epics/R3.11/Unix/share/bin/getrel /net/phebos/epics/R3.11. An existing R3.8 short form report can be copied to this new directory and used to create a database. ANL/APS is currently testing an Application Developers Source/Release control system. It is not yet ready for general distribution. Attached are the EPICS R3.11 release notes.

NONE

1994-01-19

188

Evaluation of an on farm press  

SciTech Connect

POS has evaluated the Simon-Rosedowns mini-40 farm scale press in terms of throughput, oil removal, quality of oil, and effect of seed conditions on throughput and oil quality. Preliminary indications are that the press is very reliable and rugged. Oil output of 9 to 10 litres/hour has been attained for 6 to 7% moisture seed. Throughput drops off from 25 to 15 kg/h and oil removal worsens considerably when 9 to 10% moisture seed is expelled. 3 figures.

Blake, J.A.

1982-01-01

189

Freedom House: Freedom of the Press  

NSDL National Science Digital Library

Advocacy, action, and analysis are the tenets of Freedom House, a democracy organization founded in 1941 in the United States. Their website is available in Arabic, Chinese, English, Farsi, Korean, Russian and Spanish, and is loaded with analysis. One of the focuses of Freedom House is to monitor the freedom of the press available in countries around the world. Each year they publish a survey of 194 countries' degree of free press. The report includes country scores, draft reports, an overview essay, and methodology employed in gathering the data for the survey. To view any of the reports simply click "Reports" near the top of the homepage.

2008-01-01

190

[Progresses on plant AP2/ERF transcription factors].  

PubMed

Plant AP2/ERF transcription factor with AP2/ERF domain containing 60-70 amino acids is a huge gene family present in all plant. AP2/ERF transcriptional factors are involved in various biological functions such as plant development, flower development, fruit and seed maturation, wounding, pathogen defense, high salty, drought, and so on. AP2/ERF transcription factor are involved in salicylic acid, jasmonic acid, ethylene, abscisic acid signal transduction pathways and among them. The transcription factors are cross-talk factor in stress signal pathway. This paper summarizes the most advanced researches on types, biological functions, and gene regulations of plant AP2/ERF transcription factors. PMID:22805209

Zhang, Ji-Yu; Wang, Qing-Ju; Guo, Zhong-Ren

2012-07-01

191

A comparison of peak power in the shoulder press and shoulder throw.  

PubMed

The ability to generate peak power is central for performance in many sports. Currently two distinct resistance training methods are used to develop peak power, the heavy weight/slow velocity and light weight/fast velocity regimes. When using the light weight/fast velocity power training method it was proposed that peak power would be greater in a shoulder throw exercise compared with a normal shoulder press. Nine males performed three lifts in the shoulder press and shoulder throw at 30% and 40% of their one repetition maximum (1RM). These lifts were performed identically, except for the release of the bar in the throw condition. A potentiometer attached to the bar measured displacement and duration of the lifts. The time of bar release in the shoulder throw was determined with a pressure switch. ANOVA was used to examine statistically significant differences where the level of acceptance was set at p < 0.05. Peak power was found to be significantly greater in the shoulder throw at 30% of 1 RM condition [F, (1, 23) = 2.325 p < 0.051 and at 40% of 1 RM [F, (1, 23) = 2.905 p < 0.05] compared to values recorded for the respective shoulder presses. Peak power was also greater in the 30% of 1 RM shoulder throw (510 +/- 103W) than in the 40% of 1 RM shoulder press (471 +/- 96W). Peak power was produced significantly later in the shoulder throw versus the shoulder press. This differing power reflected a greater bar velocity of the shoulder throw at both assigned weights compared with the shoulder press. PMID:12413039

Dalziel, W M; Neal, R J; Watts, M C

2002-09-01

192

Proactive AP Selection Method Considering the Radio Interference Environment  

NASA Astrophysics Data System (ADS)

In the near future, wireless local area networks (WLANs) will overlap to provide continuous coverage over a wide area. In such ubiquitous WLANs, a mobile node (MN) moving freely between multiple access points (APs) requires not only permanent access to the Internet but also continuous communication quality during handover. In order to satisfy these requirements, an MN needs to (1) select an AP with better performance and (2) execute a handover seamlessly. To satisfy requirement (2), we proposed a seamless handover method in a previous study. Moreover, in order to achieve (1), the Received Signal Strength Indicator (RSSI) is usually employed to measure wireless link quality in a WLAN system. However, in a real environment, especially if APs are densely situated, it is difficult to always select an AP with better performance based on only the RSSI. This is because the RSSI alone cannot detect the degradation of communication quality due to radio interference. Moreover, it is important that AP selection is completed only on an MN, because we can assume that, in ubiquitous WLANs, various organizations or operators will manage APs. Hence, we cannot modify the APs for AP selection. To overcome these difficulties, in the present paper, we propose and implement a proactive AP selection method considering wireless link condition based on the number of frame retransmissions in addition to the RSSI. In the evaluation, we show that the proposed AP selection method can appropriately select an AP with good wireless link quality, i.e., high RSSI and low radio interference.

Taenaka, Yuzo; Kashihara, Shigeru; Tsukamoto, Kazuya; Yamaguchi, Suguru; Oie, Yuji

193

Predicting the performance of belt filter presses using the Crown Press for laboratory simulation  

SciTech Connect

Belt filter presses (BFPs) are among the most commonly used devices to dewater wastewater sludge. The concept used by a BFP to achieve dewatered cake solids is relatively simple; however, replicating this performance in the laboratory in order to predict the performance of a BFP with reasonable reliability has proven to be a challenge. The Crown Press is one tool that has been shown to replicate the performance of anaerobically digested sludge on a BFP. This study used the Crown Press to replicate and predict the performance of waste activated sludge (WAS) from the Mauldin Road wastewater treatment plant on BFPs. Several operational variables, including belt speed, belt tension, polymer type, and polymer dose, were changed on the Crown Press to predict how the changes on the BFP would affect performance. Two polymers were chosen to be tested on the BFPs at Mauldin Road based on Crown Press predictions. The first polymer performed the same as the plant`s current polymer in the lab, and the second performed better (achieved higher final cake solids) than the current polymer. These predictions were borne out in the BFP tests, showing that the Crown Press predictions were accurate. The Crown Press predictions were also compared to the predictions made by the capillary suction time (CST) and specific resistance to filtration (SRF) tests. The Crown Press provided more information regarding the affect of polymer type and dose on cake solids than either CST or SRF. The Crown Press was shown to be a viable tool to assess potential changes in BFP performance with WAS when operational variables change.

Graham, T.M.

1999-07-26

194

U.S. BICENTENNIAL EXPOSITION PRESS CONFERENCE  

NASA Technical Reports Server (NTRS)

Fielding questions from the press concerning 3rd Century America, the Bicentennial Exposition on Science and Technology are [left to right]: Herbert J. Rowe, NASA Associate Administrator for External Affairs; Miles Ross, KSC Deputy Director and Bicentennial General Manager; Lee Scherer, KSC Director, and Paul Donnelly, KSC Director of Space Transportation System Processing and Chief of the Exposition Site Development and Operations Office.

1976-01-01

195

An Introduction to Bibliographical Press Work.  

ERIC Educational Resources Information Center

This guide to the literature of bibliographical press work is comprised of brief introductory notes on the field and this bibliography, followed by citations listed in seven categories: (1) book production, (2) handmade paper, (3) printer's ink, (4) type design, (5) book design, (6) hand printing, and (7) hand bookbinding. Introductory as well as…

Richardson, John V., Jr.

196

Metrics for Offset Printing Press Operation.  

ERIC Educational Resources Information Center

Designed to meet the job-related metric measurement needs of offset printing press operation students, this instructional package is one of six for the communication media occupations cluster, part of a set of 55 packages for metric instruction in different occupations. The package is intended for students who already know the occupational…

Cooper, Gloria S., Ed.; Magisos, Joel H., Ed.

197

When International Press Rights "Are" the News  

ERIC Educational Resources Information Center

In many countries, reporters and editors face criminal prosecution, censorship, self-censorship, exile, tax audits, loss of broadcast and publication licenses, loss of jobs, assault, and even assassination based on how they practice their profession. Press rights and human rights advocacy groups try to draw media and official attention to those…

Freedman, Eric

2006-01-01

198

Laser cutting of pressed explosives: Revision 1.  

National Technical Information Service (NTIS)

We have used a femtosecond laser beam to make cuts through small pressed pellets of six common explosives. The laser system, which produces 100 fs pulses of 820 nm light at a repitition rate of 1 kHz, was intitially developed for cutting metal. The advant...

F. Roeske R. E. Banks J. P. Armstrong M. D. Feit R. S. Lee

1998-01-01

199

Fair Trials and Free Press. Student Forum.  

ERIC Educational Resources Information Center

Outlines a role play that highlights the potential conflict between freedom of the press and the rights of defendants and victims. Students assume the roles of representative characters (police chief, newspaper editor) in a small town where a sensational murder has occurred. They also conduct a class discussion. (MJP)

Mertz, Gayle

1997-01-01

200

Communications in Agriculture: The American Farm Press.  

ERIC Educational Resources Information Center

This book studies communications in agriculture, focusing on the American farm press. As defined here, a commercial farm periodical is directed to farmers and supports itself through the sale of subscriptions or advertising. It includes local as well as regional and national periodicals. A 90-year analysis, from 1880 to 1970, was chosen because…

Evans, James F.; Salcedo, Rodolfo N.

201

Brownsville: The Reaction of the Negro Press  

ERIC Educational Resources Information Center

Describes the events that followed subsequent to the assignment of an all-black regimental unit to the Fort Brown military installation on the outskirts of Brownsville, Texas, in 1906, with reference to the reactions of the Brownsville residents, the Negro press, and white champions of the black cause, and to the actions of President Theodore…

Wynne, Lewis N.

1972-01-01

202

The Press and the Bolivian National Revolution.  

ERIC Educational Resources Information Center

Social revolutions, which frequently use the press as a propaganda weapon, have been rare in Latin America despite the striking social inequalities of the region. Only three classic socioeconomic revolutions have unfolded in the hemisphere--in Mexico in 1910, in Bolivia in 1952, and in Cuba in 1959. Bolivia attempted to effect radical reforms…

Knudson, Jerry W.

1973-01-01

203

Joining Refractory Metal Compounds by Hot Pressing.  

National Technical Information Service (NTIS)

A study was made to determine the feasibility of joining refractory metal compounds to each other and to oxide ceramics by a vacuum hot press-diffusion bonding method. Very satisfactory joins were made of ZrC to ZrB2, ZrN to ZrB2, ZrC to ZrN, and of ZrC, ...

J. E. Kelley D. H. Sumner H. J. Kelly

1969-01-01

204

Development of a Durable Press Summer Uniform.  

National Technical Information Service (NTIS)

The report describes the development of a suitable candidate durable press fabric for the summer Army uniform. Many commercial fabrics were examined and analyzed before the selection of a prototype fabric was made. The preferred candidate is a 7.0 oz/sq y...

A. M. Campbell C. J. Pope E. B. Frederick F. A. Hoffman R. D. Wells

1970-01-01

205

Reflection properties of pressed polytetrafluoroethylene powder  

Microsoft Academic Search

The reflection properties of pressed polytetrafluoroethylene powder have been under investigation by the Radio- metric Physics Division at the National Bureau of Standards for the past five years. This material has a great po- tential use, both as a standard of diffuse reflectance and as a coating for integrating spheres for applications in re- flectance spectrophotometry and other signal-averaging devices.

Victor R. Weidner; Jack J. Hsia

1981-01-01

206

Freedom of the Press: Foundations and Attitudes.  

ERIC Educational Resources Information Center

This study reports the results of a national survey of the attitudes of five demographic groups toward freedom of the press. The groups are newsmen, state legislators, high school teachers, high school students, and the general public. The survey is broken into two parts, the first dealing with general principles (e.g., support for a law against…

Gibson, Martin Leroy, Jr.

207

Mutual Suspicion: Higher Education and the Press.  

ERIC Educational Resources Information Center

Neither the typical academic nor the average journalist understands well what the other does. There has been a major shift in the way the American press treats education, and education leaders and scholars must learn to deal with the media differently. This requires openness, responsiveness, and competence in the college public affairs office.…

Footlick, Jerrold

1997-01-01

208

Does Science Get the Press It Deserves?  

ERIC Educational Resources Information Center

Discusses concerns about public understanding of science in the United Kingdom in relation to structure and content of newspapers, particularly the inadequacy of the press to be a vehicle for promoting scientific literacy within the citizenry. Argues that changes in science coverage by the media must originate from the scientific community with…

Wilkie, Tom

1991-01-01

209

The Moral Universes of Libertarian Press Theory.  

ERIC Educational Resources Information Center

Uses Kantian logic to analyze the statement of Libertarian press theory "Truth beats falsehood in a free marketplace of ideas" as a definition, an observation, and a universal truth. Notes three corresponding moral universes, with differing ethical obligations. Discusses strengths and weaknesses of each. Cautions media ethics analysts against…

Wuliger, Gregory T.

1991-01-01

210

In response to a lawsuit filed by the Associated Press, artist Shepard Fairey countersues  

NSDL National Science Digital Library

Artist Files Lawsuit Against the Associated Press Over Image of Obamahttp://www.nytimes.com/2009/02/10/arts/design/10fair.htmlFair Use Project Files Suit Against The Associated Press on Behalf of Artist Shepard Fairey [pdf]http://cyberlaw.stanford.edu/node/6061Artist questions police's timing of his arrest on graffiti chargeshttp://www.boston.com/ae/theater_arts/articles/2009/02/10/cultural_acclaim_residents_anger/Lawrence Lessig: Remixhttp://fora.tv/2009/01/14/Lawrence_Lessig_Remix#chapter_01Banned in Bostonhttp://www.bu.edu/library/guides/boston/banned.htmlObey Giant [Macromedia Flash Player]http://obeygiant.com/Last Friday, contemporary artist Shepard Fairey was in Boston to celebrate the opening of his new gallery show at the Institute of Contemporary Art. He was probably not expecting to get arrested by the Boston Police Department, but that was exactly what happened on his way to the Institute's home in the Fort Point Channel neighborhood. Fairey was arrested on graffiti-related charges, and he later pled not guilty. It was the end of a busy week for Fairey, as The Associated Press sued him on Thursday for copyright infringement. The Associated Press (AP) has made the claim that he appropriated a 2006 AP photograph taken by Mannie Garcia for his iconic "Hope" poster, which became a popular image during President Barack Obama's campaign for president. This Monday, Fairey countersued the Associated Press, asking a judge to declare that he is in fact protected from copyright infringement claims as regards his use of the photo in question. The whole situation gets a bit more complicated as Garcia has recently stated he holds the copyright for the photograph. It remains to be seen how things will turn out for all the parties involved, but in a recent interview Garcia remarked, "I don't condone people taking things, just because they can, off the Internet. But in this case I think it's a very unique question."The first link will take readers to an article from this Tuesday's New York Times which talks about Fairey's current situation and the countersuit he recently filed against the AP. The second link leads to the text of the suit filed against the AP in support of Fairey's case by the Fair Use Project at Stanford University's Center for Internet and Society. The third link will take users to an article from this Tuesday's Boston Globe. The article takes a look at both Fairey's arrest and the reaction of Boston residents to his art. Moving on, the fourth link leads to a talk by Professor Lawrence Lessig on how copyright law might be transformed and modified for the 21st century. The fifth link leads to a delightful list from the Boston University Libraries about things that have been "banned in Boston" during the past several centuries. While Fairey's work wasn't banned per se, many other things have not been so lucky, including plays, pamphlets, and books like Theodore Dreiser's "An American Tragedy". The final link will take users to Fairey's own homepage, where they can view some of his works and learn more about his background.

Grinnell, Max

2009-02-13

211

Path Deviation Equations in AP-Geometry  

NASA Astrophysics Data System (ADS)

Recently, it has been shown that Absolute Parallelism (AP) geometry admits paths that are naturally quantized. These paths have been used to describe the motion of spinning particles in a background gravitational field. In case of a weak static gravitational field limits, the paths are applied successfully to interpret the discrepancy in the motion of thermal neutrons in the Earth's gravitational field (COW-experiment). The aim of the present work is to explore the properties of the deviation equations corresponding to these paths. In the present work the deviation equations are derived and compared to the geodesic deviation equation of the Riemannian geometry.

Wanas, M. I.; Kahil, M. E.

2006-02-01

212

APS Living History Project Continues to Grow  

NSDL National Science Digital Library

This is an article from The Physiologist. The APS Living History Project continues to gain traction as members invite senior members at their institutions to reminisce about their careers. Our membersÃÂ efforts are consistent with CouncilÃÂs goal when it initiated the program ÃÂ to chronicle the exploits and experiences of senior members of the Society. Over the last several years, we have lost a number of eminent physiologists who made significant contributions to the discipline of physiology and to the Society. The Living History Project is one way to capture the images, experiences and wisdom of our senior members for the benefit of future generations of physiologists.

2008-02-01

213

Ozone mitigation tests at the APS  

SciTech Connect

Ozone is generated in the APS experimental stations whenever the x-ray beam has a chance to interact with air. Ozone concentrations in an experimental station have to be below a certain defined limit (current OSHA regulations specify 0.08 ppm as the maximum limit) before an experimenter can reenter the hutch. This limit is said to be currently under study for a downward adjustment. One method of depleting the ozone generated in an experimental station is mitigation through either adsorption or direct destruction. In recent tests, both methods were tried using commercially available units. Test results and some analytical predictions are presented.

Kuzay, T.M.; Collins, J.T.; Pisharody, M.; Job, P.K.; Wang Zhibi

1996-09-01

214

Predicting the Performance of Belt Filter Presses Using the Crown Press for Laboratory Simulation.  

National Technical Information Service (NTIS)

Belt filter presses (BFPs) are among the most commonly used devices to dewater wastewater sludge. The concept used by a BFP to achieve dewatered cake solids is relatively simple; however, replicating this performance in the laboratory in order to predict ...

T. M. Graham

1999-01-01

215

Electromagnetic field analysis of septum magnet for APS positron accumulator ring  

SciTech Connect

This report consists of three parts. The first part describes a numerical analysis method for the electromagnetic field analysis of a septum magnet. A novel improvement to the treatment of exciting currents in the time-domain is proposed. The second part discusses numerical predictions of the electromagnetic characteristics of the APS PAR septum. The time variations of stray field and eddy currents are shown for three magnet designs. The last part explores how decreasing the septum material conductivity affects the stray field. The decrease of conductivity may be caused by an inadequate manufacturing of the septum material. The significance of a high quality septum, or flat interface between copper and iron, is emphasized from a point of view of stray field. An ideal method for joining two different metals without distortion, called HIP (Hot Isostatic Pressing), is introduced and recommended based on the authors` experience.

Yokoi, Toshiaki; Turner, L.R.

1995-07-01

216

Commerical Laundry, Drycleaning and Pressing Machine Manufacturing: 1997 Economic Census Manufacturing Industry Series  

NSDL National Science Digital Library

The US Department of Commerce Census Bureau has released the few in a series of several hundred reports on individual industries in the manufacturing sector from the 1997 Economic Census. The 1997 Economic Census series on the Commercial Laundry, Drycleaning, and Pressing Machine Manufacturing does not include state comparisons but reports on total capital expenditures in Illinois as well as the US as a whole.

1999-01-01

217

The APS control system network upgrade.  

SciTech Connect

When it was installed,the Advanced Photon Source (APS) control system network was at the state-of-the-art. Different aspects of the system have been reported at previous meetings [1,2]. As loads on the controls network have increased due to newer and faster workstations and front-end computers, we have found performance of the system declining and have implemented an upgraded network. There have been dramatic advances in networking hardware in the last several years. The upgraded APS controls network replaces the original FDDI backbone and shared Ethernet hubs with redundant gigabit uplinks and fully switched 10/100 Ethernet switches with backplane fabrics in excess of 20 Gbits/s (Gbps). The central collapsed backbone FDDI concentrator has been replaced with a Gigabit Ethernet switch with greater than 30 Gbps backplane fabric. Full redundancy of the system has been maintained. This paper will discuss this upgrade and include performance data and performance comparisons with the original network.

Sidorowicz, K. v.; Leibfritz, D.; McDowell, W. P.

1999-10-22

218

The Electronic ApJ Letters  

NASA Astrophysics Data System (ADS)

In its 100th year, the Astrophysical Journal has gone to electronic publication of the Letters section. Starting with the July, 1995, issues the full text of the Letters can be found at http://www.aas.org/ApJ/. The electronic journal is published every 10 days and comes out one month before the issue date of the paper version. The special features of the electronic version include linking to the abstracts of the astronomical literature through the Astrophysics Data System, a strong search engine, easy navigation within the electronic version and forward referencing. These features and other functionality, which has been added as a result of reader feedback, make the electronic ApJ Letters the most effective scholarly journal on the World Wide Web today. As of January, 1996, a new version of the Letters with even more functionality will be made available and will be demonstrated at the San Antonio meeting. Future plans are to bring the full Astrophysical Journal plus the Supplements on line by January 1997. At that point 40 percent of the world's astronomical literature will be available electronicaly. Remember, user's comments will help to shape the future directions of the electronic journals.

Boyce, P. B.

1995-12-01

219

Proximal femoral canal shape is more accurately assessed on AP hip radiographs than AP pelvis radiographs in primary hip osteoarthritis.  

PubMed

The objectives of the present study were to determine whether differences in the radiographic appearance of the of the proximal femoral canal exist on corresponding AP pelvis and AP hip radiographs, and whether radiographic assessment of canal shape is accurate with reference to computed tomography (CT). In a retrospective study, corresponding radiographs and CT scans of 100 consecutive patients with primary hip OA were evaluated. Active shape modelling (ASM) was performed to assess the variation in proximal femoral canal shape and to identify differences between AP hip and AP pelvis views. Differences in the medial cortical flare between radiographs and CT were quantified using least squares curve fitting. ASM identified significant differences in the assessment of canal shape on corresponding AP hip and AP pelvis views. Curve fitting demonstrated a good agreement between AP hip radiographs and CT. Agreement between AP pelvis radiographs and CT was less good. In contrast to AP pelvis radiographs, AP hip radiographs allow a more accurate and reliable assessment of proximal femoral canal shape in the frontal plane in primary hip OA. Our findings may improve stem fit in total hip arthroplasty without the routine use of CT. PMID:23813170

Merle, Christian; Waldstein, Wenzel; Gregory, Jennifer S; Goodyear, Simon R; Aspden, Richard M; Aldinger, Peter R; Murray, David W; Gill, Harinderjit S

2013-01-01

220

Depolarization-induced suppression of spontaneous release in the avian midbrain  

PubMed Central

Spontaneous neurotransmitter release has been considered synaptic ‘noise’ for decades. Recent work, however, suggests that synaptic events arising from action-potential (AP) independent neurotransmitter release contribute to synaptic function in a manner qualitatively different from AP-dependent release. We investigated the effect of somatic depolarization on spontaneous neurotransmitter release in neurons of the external portion of the chicken inferior colliculus (EX). We found this manipulation affects spontaneous but not AP-dependent release onto EX neurons in a retrograde manner. This depolarization-induced suppression of spontaneous release requires activation of N-methyl-D-aspartate receptors on the presynaptic cell and postsynaptic calcium-dependent vesicle fusion. These results show a novel form of plasticity that allows the postsynaptic cell to selectively modulate spontaneous neurotransmitter release of its afferent inputs.

Penzo, Mario Alexander; Pena, Jose Luis

2011-01-01

221

9. INTERIOR VIEW OF EYE PRESS AREA; TO LEFT IS ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

9. INTERIOR VIEW OF EYE PRESS AREA; TO LEFT IS A TWO-BAY SLOTTED TYPE FURNACE, TO CENTER IS EYE PRESS, TO RIGHT IS CURCULAR SAW - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

222

Tank 241AP108 grab sampling and analysis plan  

Microsoft Academic Search

This Sampling and Analysis Plan (SAP) will identify characterization objectives for sample collection, laboratory analytical evaluation, and reporting requirements for tank 241-AP-108 (AP 108). It is written in accordance with the Tank 241-AP-108 Tank Characterization Plan, the Tank Safety Screening Data Quality Objective, the 242-A Evaporator Liquid Effluent Retention Facility Data Quality Objectives, and the Data Quality Objectives for Tank

Fluor Daniel Hanford

1997-01-01

223

Glass Coats For Hot Isostatic Pressing  

NASA Technical Reports Server (NTRS)

Surface voids sealed from pressurizing gas. Coating technique enables healing of surface defects by hot isostatic pressing (HIP). Internal pores readily closed by HIP, but surface voids like cracks and pores in contact with pressurizing gas not healed. Applied to casting or weldment as thick slurry of two glass powders: one melts at temperature slightly lower than used for HIP, and another melts at higher temperature. For example, powder is glass of 75 percent SiO2 and 25 percent Na2O, while other powder SiO2. Liquid component of slurry fugitive organic binder; for example, mixture of cellulose acetate and acetone. Easy to apply, separates voids from surrounding gas, would not react with metal part under treatment, and easy to remove after pressing.

Ecer, Gunes M.

1989-01-01

224

Reducing VOC Press Emission from OSB Manufacturing  

SciTech Connect

Current regulations require industry to meet air emission standards with regard to particulates, volatile organic compounds (VOCs), hazardous air pollutants (HAPs) and other gases. One of many industries that will be affected by the new regulations is the wood composites industry. This industry generates VOCs, HAPs, and particulates mainly during the drying and pressing of wood. Current air treatment technologies for the industry are expensive to install and operate. As regulations become more stringent, treatment technologies will need to become more efficient and cost effective. The overall objective of this study is to evaluate the use of process conditions and chemical additives to reduce VOC/HAPs in air emitted from presses and dryers during the production of oriented strand board.

Dr. Gary D. McGinnis; Laura S. WIlliams; Amy E. Monte; Jagdish Rughani: Brett A. Niemi; Thomas M. Flicker

2001-12-31

225

Synaptic vesicle recycling at CNS synapses without AP-2  

PubMed Central

Synaptic vesicles (SVs) are composed of ~10 types of transmembrane proteins that must be recycled following exocytosis of neurotransmitter. The mechanisms for resorting these proteins into synaptic vesicles once incorporated into the plasma membrane following exocytosis are poorly understood. The adaptor complex AP-2 is the major clathrin-associated adaptor for cargo recognition at the plasma membrane. Here we have investigated its role in synaptic vesicle endocytosis. shRNA-mediated knockdown of the AP-2 complex results in a ~96% reduction of this protein complex in primary neurons. We used simultaneous expression of shRNA and pHluorin-tagged vesicle components to show that the absence of AP-2 significantly slows, but does not prevent the endocytosis of 4 of the major synaptic vesicle transmembrane proteins. We show that in the absence of AP-2, the AP-1 adaptor complex appears to functionally substitute for AP-2, but results in complex internalization kinetics that are now sensitive to the ARF-GEF inhibitor Brefeldin-A. Simultaneous removal of both AP-2 and AP-1 prevents this compensatory substitution and results in slowed but functional endocytosis. These results demonstrate that in the absence of AP-2 SV proteins still become endocytosed and synaptic vesicle recycling remains operational.

Kim, Sung Hyun; Ryan, Timothy. A.

2009-01-01

226

Iodine Volatility and pH Control in the AP-600 Reactor  

SciTech Connect

Two design-basis accidents for the AP-600 reactor are formulated and evaluate~ in which significant bypass of the principal pH control system occurs. Some iodine released from the reactor primary system is retained in the Incontainment Refaeling Water Storage Tank (IRWST) water, never entering the containment where trisodium phosphate produces a high pH. Some of this iodine is volatilized and is transported into the reactor containment airspace. in the worst case, a small fraction is released to the environment at design-basis leak rate, yielding a total cumulative iodine release at 30 days of 0.0352 mol (0.023% of core iodine inventory) due to the iodine volatilization bypassing the pH control system. No fission product removal in the containment atmosphere (i.e., natural deposition sprays) is considered.

Beahm, E.C.; Weber, C.F.

1998-10-01

227

Project W-211, initial tank retrieval systems, description of operations for 241-AP-102 and 241-AP-104  

SciTech Connect

The primary purpose of the Initial Tank Retrieval Systems (ITRS) is to provide systems for retrieval of radioactive wastes stored in underground double-shell tanks (DSTS) for transfer to alternate storage, evaporation, pretreatment or treatment, while concurrently reducing risks associated with safety watch list and other DSTs. This Description of Operations (DOO) defines the control philosophy for the waste retrieval system for tanks 241-AP-102 (AP-102) and 241-AP-104 (AP-104). This DOO will provide a basis for the detailed design of the Retrieval Control System (RCS) for AP-102 and AP-104 and establishes test criteria for the RCS. The test criteria will be used during qualification testing and acceptance testing to verify operability.

RIECK, C.A.

1999-02-25

228

Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles  

US Patent & Trademark Office Database

The invention relates to a microparticulate system for the delayed and controlled release of active principles (AP) whose absorption window in vivo is essentially limited to the upper parts of the gastrointestinal tract, this system being intended for oral administration. The object of the invention is to provide a system ensuring that the AP is released with certainty by means of a dual mechanism of "time-dependent" and "pH-dependent" release. To achieve this object, the invention proposes a multimicrocapsular oral galenical form which is designed so as to guarantee therapeutic efficacy, and in which the release of the AP is governed by a dual release triggering mechanism that is "time-triggering" and "pH-triggering". This system comprises of microcapsules (200 to 600 .mu.m) comprising a core of AP coated with a film (maximum 40% by weight) comprising a hydrophilic polymer A (Eudragit.RTM. L) and a hydrophobic compound B (vegetable wax, melting point=40-90.degree. C.), B/A being between 0.2 and 1.5. These microcapsules have a dissolution behavior in vitro such that, at a constant pH of 1.4, a latency phase of between 1 and 5 hours is observed, followed by a release of the AP, and such that the change from pH 1.4 to pH 6.8 results in a release of the AP without a latency period in vitro.

2012-01-24

229

Graphic Arts: The Press and Finishing Processes. Third Edition.  

ERIC Educational Resources Information Center

This document contains teacher and student materials for a course in graphic arts concentrating on printing presses and the finishing process for publications. Seven units of instruction cover the following topics: (1) offset press systems; (2) offset inks and dampening chemistry; (3) offset press operating procedures; (4) preventive maintenance…

Crummett, Dan

230

WET PLANT FRACTIONATION: UTILIZATION OF PRESSED ALFALFA SILAGE 1  

Microsoft Academic Search

SUMMARY Three lactation trials and two digestion trials were performed comparing mechanically pressed ensiled alfalfa with similar material which was field-wilted before ensiling. Pressed alfalfa contained significantly (P<.05) less dry matter, crude protein, and ash; and more cell wall constituents than the wilted forage, and these trends were transposed into their resulting silages. The pressed silage con- tained a greater

J. R. Russell; J. P. Hurst; N. A. Jorgensen; G. P. Barrington

2010-01-01

231

PRESS DEWATERING OF BROWN COAL: PART 1EXPLORATORY STUDIES  

Microsoft Academic Search

The large water content of brown coal can be reduced by press dewatering with much lower energy requirement than by alternative methods. The cost of the press need.ed increases with the required pressing pressure, which is det e rmfned by the coal properties. The results of experiments on Victorian brown coals are interpreted with supporting theory to give these properties,

P. J. Banks; D. R Burton

1989-01-01

232

APS/NIDDK Minority Travel Fellows Attend the 2008 APS Intersociety Meeting: The Integrative Biology of Exercise  

NSDL National Science Digital Library

This is an article from The Physiologist. The APS regularly awards Travel Fellowships for underrepresented minority scientists and students to attend APS scientific meetings with funds provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). These fellowships provide funds for registration, transportation, meals, and lodging. Seven fellows attended the APS Intersociety Meeting, ÃÂThe Biology of Exercise VÃÂ in Hilton Head, SC from September 24-27, 2008.

2009-02-01

233

Soil-Release Finishing of Textiles: A Status Report.  

National Technical Information Service (NTIS)

Recent developments in the soil-release finishing of 100% polyester, polyester-cotton blended, and all cotton durable press fabrics have been reviewed. A survey of various commercial soil-release finishes available in the world market is presented. The ch...

T. K. Das A. K. Kulshreshtha

1978-01-01

234

Control units for APS power supplies  

SciTech Connect

The Advanced Photon Source (APS) accelerator facility is made up of five major subsystems in addition to the linac: the positron accumulator ring (PAR), low energy transport (LET), booster synchrotron (SYNCH), high energy transport (HET), the storage ring (SR). Each subsystem has multiple magnet power supply combinations, some requiring multiple of operation. These magnet and power supply combinations computer controlled and monitored. The power supply control unit (PSCU) is the first layer of hardware and software above the power supply itself and is described in this paper. The description includes the basic philosophy for each of operation and how it influences the topology and of implementing control. The design of the analog reference blocks (ARBs) influenced the design of other custom functions well as the feedback controls for vibration and other dynamic corrections. The command set supported by the PSCU is discussed.

Despe, O.D.; Saunders, C.; McGhee, D.G.

1993-07-01

235

Metallized solid rocket propellants based on AN/AP and PSAN/AP for access to space  

NASA Astrophysics Data System (ADS)

Solid rocket propellants based on dual mixes of inorganic crystalline oxidizers (ammonium nitrate (AN) and ammonium perchlorate (AP)) with binder and a mixture of micrometric-nanometric aluminum were investigated. Ammonium nitrate is a low-cost oxidizer, producing environment friendly combustion products but with lower specific impulse compared to AP. The better performance obtained with AP and the low quantity of toxic emissions obtained by using AN have suggested an interesting compromise based on a dual mixture of the two oxidizers. To improve the thermal response of raw AN, different types of phase stabilized AN (PSAN) and AN/AP co-crystals were investigated.

Levi, S.; Signoriello, D.; Gabardi, A.; Molinari, M.; Galfetti, L.; Deluca, L. T.; Cianfanelli, S.; Klyakin, G. F.

2009-09-01

236

The AP2-like gene NsAP2 from water lily is involved in floral organogenesis and plant height.  

PubMed

APETALA2 (AP2) genes are ancient and widely distributed among the seed plants, and play an important role during the plant life cycle, acting as key regulators of many developmental processes. In this study, an AP2 homologue, NsAP2, was characterized from water lily (Nymphaea sp. cv. 'Yellow Prince') and is believed to be rather primitive in the evolution of the angiosperms. In situ RNA hybridization showed that NsAP2 transcript was present in all regions of the floral primordium, but had the highest level in the emerging floral organ primordium. After the differentiation of floral organs, NsAP2 was strongly expressed in sepals and petals, while low levels were found in stamens and carpels. The NsAP2 protein was suggested to be localized in the cell nucleus by onion transient expression experiment. Overexpression of NsAP2 in Arabidopsis led to more petal numbers, and Arabidopsis plants expressing NsAP2 exhibited higher plant height, which may be a result of down-regulated expression of GA2ox2 and GA2ox7. Our results indicated that the NsAP2 protein may function in flower organogenesis in water lily, and it is a promising gene for plant height improvement. PMID:22591856

Luo, Huolin; Chen, Sumei; Jiang, Jiafu; Teng, Nianjun; Chen, Yu; Chen, Fadi

2012-07-01

237

Crack-Free, Nondistorting Can For Hot Isostatic Pressing  

NASA Technical Reports Server (NTRS)

New method of canning specimens made of composites of arc-sprayed and plasma-sprayed tape reduces outgassing and warping during hot isostatic pressing. Produces can having reliable, crack-free seal and thereby helps to ensure pressed product of high quality. Specimen placed in ring of refractory metal between two face sheets, also of refractory metal. Assembly placed in die in vacuum hot press, where simultaneously heated and pressed until plates become diffusion-welded to ring, forming sealed can around specimen. Specimen becomes partially densified, and fits snugly within can. Ready for further densification by hot isostatic pressing.

Juhas, John J.

1991-01-01

238

Effect of hot pressing additives on the leachability of hot pressed sodium hydrous titanium oxide  

SciTech Connect

Sodium hydrous titanium oxide is an ion exchange resin which can be used for immobilizing medium level waste (MLW) liquors. When hot pressed, it undergoes conversion to a ceramic. Three low melting point materials (borax, bismuth trioxide, and a mixture of PbO/CuO) were added to the (Na)HTiO and the effect that each of these had on aiding densification was assessed. Hot pressing temperature, applied pressure, and percentage addition of hot pressing aid were varied. Percentage open porosity, flexural strength, and leachability were measured. There was a linear relationship between the percentage open porosity and the logarithm of the leach rate for a constant percentage addition of each additive.

Valentine, T.M.; Sambell, R.A.J.

1980-01-01

239

AP-42 ADDITIONS AND REVISIONS - PAVED AND UNPAVED ROAD DUST  

EPA Science Inventory

This project develops emission factors, etc., for paved and unpaved roads which are incorporated into AP-42. AP42 is a massive collection of material which describes processes which generate air emissions and presents emission factors and control effectiveness information. As re...

240

AP-42 ADDITIONS AND REVISIONS - LANDFILLS (COMBUSTION CONTROLS)  

EPA Science Inventory

This project develops emission factors, etc., for landfills, in particular for combustion devices fed by landfill gas, for incorporation into AP-42. AP-42 is a massive collection of information concerning processes which generate air emissions and presents emission factors and co...

241

AP-42 ADDITIONS AND REVISIONS - RUBBER PRODUCTS MANUFACTURING  

EPA Science Inventory

This project develops emission factors, etc., for the rubber products industry which are appended to AP-42. AP42 is a massive collection of material which describes processes which generate air emissions and presents emission factors and control effectiveness information. As res...

242

Raising Rigor, Getting Results: Lessons Learned from AP Expansion  

ERIC Educational Resources Information Center

Advanced Placement (AP), which enables high school students to take introductory college-level courses, is the nation's oldest example of a rigorous, common curriculum. Students who score well on AP exams are more likely to persist in college and earn a degree. The Advanced Placement Expansion project of the National Governors Association Center…

Wakelyn, David

2009-01-01

243

75 FR 75666 - Advanced Placement (AP) Test Fee Program  

Federal Register 2010, 2011, 2012, 2013

...applications for the AP Test Fee FY 2011 competition. That notice established...reopening the AP Test Fee FY 2011 competition to eligible applicants...Intergovernmental Review: February 22, 2011. FOR FURTHER INFORMATION CONTACT: Francisco Ramirez, U.S. Department of...

2010-12-06

244

Tank 241AP104 Grab Sampling and Analysis Plan  

Microsoft Academic Search

This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for samples obtained from tank 241-AP-104. The purpose of this sampling event is to obtain information about the characteristics of the contents of 241-AP-104 required to provide sample material to the Waste Treatment Contractor. Grab samples will be obtained from riser

2000-01-01

245

AP-102/104 Retrieval control system qualification test procedure  

SciTech Connect

This Qualification Test Procedure documents the results of the qualification testing that was performed on the Project W-211, ''Initial Tank Retrieval Systems,'' retrieval control system (RCS) for tanks 241-AP-102 and 241-AP-104. The results confirm that the RCS has been programmed correctly and that the two related hardware enclosures have been assembled in accordance with the design documents.

RIECK, C.A.

1999-05-18

246

The development of beam current monitors in the APS  

SciTech Connect

The Advanced Photon Source (APS) is a third-generation 7-GeV synchrotron radiation source. The precision measurement of beam current is a challenging task in high energy accelerators, such as the APS, with a wide range of beam parameters and complicated noise, radiation, and thermal environments. The beam pulses in the APS injector and storage ring have charge ranging from 50pC to 25nC with pulse durations varying from 30ps to 30ns. A total of nine non- intercepting beam current monitors have been installed in the APS facility (excluding those in the linac) for general current measurement. In addition, several independent current monitors with specially designed redundant interlock electronics are installed for personnel safety and machine protection. This paper documents the design and development of current monitors in the APS,. discusses the commissioning experience in the past year, and presents the results of recent operations.

Wang, X.; Lenkszus, F.; Rotela, E.

1995-07-01

247

AP1 Transcription Factors in Epidermal Differentiation and Skin Cancer  

PubMed Central

AP1 (jun/fos) transcription factors (c-jun, junB, junD, c-fos, FosB, Fra-1, and Fra-2) are key regulators of epidermal keratinocyte survival and differentiation and important drivers of cancer development. Understanding the role of these factors in epidermis is complicated by the fact that each protein is expressed, at different levels, in multiple cells layers in differentiating epidermis, and because AP1 transcription factors regulate competing processes (i.e., proliferation, apoptosis, and differentiation). Various in vivo genetic approaches have been used to study these proteins including targeted and conditional knockdown, overexpression, and expression of dominant-negative inactivating AP1 transcription factors in epidermis. Taken together, these studies suggest that individual AP1 transcription factors have different functions in the epidermis and in cancer development and that altering AP1 transcription factor function in the basal versus suprabasal layers differentially influences the epidermal differentiation response and disease and cancer development.

Eckert, Richard L.; Adhikary, Gautam; Young, Christina A.; Jans, Ralph; Crish, James F.; Xu, Wen; Rorke, Ellen A.

2013-01-01

248

Yttrium. alpha. -sialon ceramics by hot isostatic pressing and post-hot isostatic pressing  

Microsoft Academic Search

This paper reports on dense α-sialon materials that were produced by hot isostatic pressing (HIP) and post-hot isostatic pressing (post-HIP) using composition with the formula Yâ(Si{sub 12-4.5x}), Al{sub 4.5x}-O{sub 1.5x},N{sub 16-1.5x} with 0.1 ⤠x ⤠0.9 and with the same compositions with extra additions of yttria and aluminum nitride. X-ray diffraction analyses show how the phase content changes from

Alena Bartek; T. Johansson; T. Ekstrom; H. Herbertsson

1992-01-01

249

STS-114: Discovery Post MMT Press Conference  

NASA Technical Reports Server (NTRS)

This press conference focuses on the outcome of the Mission Management Team (MMT) meeting. The launch and status of the Space Shuttle Discovery is discussed. George Diller from NASA Public Affairs introduces the panel which consists of: Wayne Hale, Space Shuttle Program Deputy Manager and Mike Wetmore, Director of Space Shuttle Processing at Nasa Kennedy Space Center. The news media asks questions about the history of the low level sensors in the hydrogen tank, the cryogenic atmosphere around the sensors, troubleshooting, astronaut activities, possible rollback procedures.

2005-01-01

250

Residual radiation studies at AP0  

SciTech Connect

The radiation environment at the NuMI experiment has received a lot of attention in the last few years in preparation for project construction. One important issue is the induced radioactivation of the components in the beam line and the shielding materials. This arises from irradiation by hadrons that are generated in the target. Since the level of the residual activity has to be considered when determining access procedures for maintenance during NuMI operation, an understanding of the properties of the remnant radiation is important. To this end, experimental studies were performed in the target vault at AP0 which is similar in design to the NuMI target area. Here 120 GeV protons bombard a target, generating the hadrons that produce the induced radioactivity. Two sets of samples each consisting of three small cylindrical or rectangular solids of iron and steel, one sample of aluminum, and one of concrete were irradiated. One set was hung just below the bottom of a module near the lithium lens (in-vault), and the other was placed on top of the modules downstream of this location (above-vault), just beneath the movable concrete roof of the vault at AP0. Further, four thin activation foils of Au, Au+Cd, In, and Al (along with small disks of the same iron, aluminum, and concrete samples discussed above) were mounted on four 10.2 cm diameter Al disks, one placed on the in-vault module and three at above-vault downstream locations as well. The radioactivity of all these materials on the 10.2 cm Al disks was determined at the Radioisotope Analysis Facility in an attempt to characterize the radionuclides produced during irradiation. The activities of the thin foils were employed in an effort to unfold a spectrum of the neutrons produced during the hadronic cascades in the target. The MARS Monte Carlo code (MO95, MO00) was used to predict and analyze the residual radiation produced during the beam irradiation. New subroutines have been developed for the MARS14 version providing reliable estimation of residual dose rates in arbitrary composite materials for arbitrary irradiation and cooling times (RA01). The results of the simulations have been compared with the measurements in Ref. (RA01) and this comparison will be summarized here.

Alexander J Elwyn et al.

2002-06-19

251

APS Position Statements- APS Guiding Principles for the Care and Use of Vertebrate Animals in Research and Training  

NSDL National Science Digital Library

The Guiding Principles for the Care and Use of Vertebrate Animals in Research and Training are an updated version of a document first adopted by the APS Council in 1953. The Guiding Principles represent a code of ethics for APS members who work with animals. They provide a framework intended to promote the humane treatment of animals and are also used to evaluate research submitted for publication in APS journals. The update is intended to clarify certain elements of the Guiding Principles and make them easier to apply in practical situations. In addition, because the Guiding Principles are based upon U.S. animal welfare requirements, the update adds provisions to address the fact that other countries have different animal welfare requirements. This change was needed because of the increasing number of physiologists from around the world who are joining the APS and submitting articles for publication in APS journals.

2010-07-16

252

Dynamics of mat consolidation during pressing: what we've learned with our in-press radiation system for pressing wood composites  

Microsoft Academic Search

We have designed a radiation-based system for density measurement of wood composites during pressing. During pressing, heat and mass transfer, consolidation speed and mat characteristics interact to produce a density distribution in the mat that is typified by high surface density and low core density. Measuring density of the wood mat during consolidation is a key parameter for understanding subsequent

Paul M. Winistorfer; William W. Moschler

1996-01-01

253

High pressure reverse flow APS engine  

NASA Technical Reports Server (NTRS)

A design and test demonstration effort was undertaken to evaluate the concept of the reverse flow engine for the APS engine application. The 1500 lb (6672 N) thrust engine was designed to operate on gaseous hydrogen and gaseous oxygen propellants at a mixture ratio of 4 and to achieve the objective performance of 435 sec (4266 Nsec/kg) specific impulse. Superimposed durability requirements called for a million-cycle capability with 50 hours duration. The program was undertaken as a series of tasks including the initial preliminary design, design of critical test components and finally, the design and demonstration of an altitude engine which could be used interchangeably to examine operating parameters as well as to demonstrate the capability of the concept. The program results are reported with data to indicate that all of the program objectives were met or exceeded within the course of testing on the program. The analysis effort undertaken is also reported in detail and supplemented with test data in some cases where prior definitions could not be made. The results are contained of these analyses as well as the test results conducted throughout the course of the program. Finally, the test data and analytical results were combined to allow recommendations for a flight weight design. This preliminary design effort is also detailed.

Senneff, J. M.

1972-01-01

254

Diagnostics for the APS undulator test line  

SciTech Connect

One of the research and development thrusts at the Advanced Photon Source (APS) is to use an rf gun as a low-emittance electron source for injection into the 100- to 650-MeV linac subsystem and subsequent transport to an undulator test area. This configuration would combine the acceleration capability of the 200-MeV S-band electron linac and the in-line 450-MeV positron linac that normally provide positrons to the positron accumulator ring (PAR). A transport line that bypasses the PAR will bring the electrons to the undulator test area. Characterization techniques will be discussed for the electron beam with a normalized, rms emittance of <10 {pi} mm mrad (l{sigma}) at micropulse charges of up to 350 pC and micropulse durations of {approximately}5 ps (FWHM). Preservation of such beam properties will be critical. The diagnostics planned, with resolutions in parentheses, include the beam position monitors based on stripline pickups (100 {mu}m), current monitors based on a transformer (60 {mu}A), beam profile monitors (25 {mu}m FWHM), and bunch length monitor based on a streak camera (2 ps). Tests proposed include measurement of particle beam transport effects (at one-tenth the storage ring beam rigidity) caused by small undulator field errors.

Lumpkin, A.H.; Ciarlette, D.; Kahana, E.; Patterson, D.; Sellyey, W.; Wang, X.

1993-11-01

255

Actes illocutoires et discours de la presse ecrite (Illocutionary Acts and the Press).  

ERIC Educational Resources Information Center

This study investigates the applicability of the speech act theory to written discourse, specifically that of the press. A survey of Searle's taxonomy leads to the suggestion that the constituent statements of most newspaper articles belong to the class of illocutionary acts he calls "representatives." In consideration of the basic characteristic…

Duda, Richard

256

Vinpocetine inhibits glutamate release induced by the convulsive agent 4-aminopyridine more potently than several antiepileptic drugs.  

PubMed

4-Aminopyridine (4-AP) is a convulsing agent that in vivo preferentially releases Glu, the most important excitatory amino acid neurotransmitter in the brain. Here the ionic dependence of 4-AP-induced Glu release and the effects of several of the most common antiepileptic drugs (AEDs) and of the new potential AED, vinpocetine on 4-AP-induced Glu release were characterized in hippocampus isolated nerve endings pre-loaded with labelled Glu ([3H]Glu). 4-AP-induced [3H]Glu release was composed by a tetrodotoxin (TTX) sensitive and external Ca2+ dependent fraction and a TTX insensitive fraction that was sensitive to the excitatory amino acid transporter inhibitor, TBOA. The AEDs: carbamazepine, phenytoin, lamotrigine and oxcarbazepine at the highest dose tested only reduced [3H]Glu release to 4-AP between 50-60%, and topiramate was ineffective. Vinpocetine at a much lower concentration than the above AEDs, abolished [3H]Glu release to 4-AP. We conclude that the decrease in [3H]Glu release linked to the direct blockade of presynaptic Na+ channels, may importantly contribute to the anticonvulsant actions of all the drugs tested here (except topiramate); and that the significantly greater vinpocetine effect in magnitude and potency on [3H]Glu release when excitability is exacerbated like during seizures, may involve the increase additionally exerted by vinpocetine in some K+ channels permeability. PMID:21737246

Sitges, M; Sanchez-Tafolla, B M; Chiu, L M; Aldana, B I; Guarneros, A

2011-10-01

257

Scholarly literature and the press: scientific impact and social perception of physics computing  

NASA Astrophysics Data System (ADS)

The broad coverage of the search for the Higgs boson in the mainstream media is a relative novelty for high energy physics (HEP) research, whose achievements have traditionally been limited to scholarly literature. This paper illustrates the results of a scientometric analysis of HEP computing in scientific literature, institutional media and the press, and a comparative overview of similar metrics concerning representative particle physics measurements. The picture emerging from these scientometric data documents the relationship between the scientific impact and the social perception of HEP physics research versus that of HEP computing. The results of this analysis suggest that improved communication of the scientific and social role of HEP computing via press releases from the major HEP laboratories would be beneficial to the high energy physics community.

Pia, M. G.; Basaglia, T.; Bell, Z. W.; Dressendorfer, P. V.

2014-06-01

258

Biochemical dissection of AP-1 recruitment onto Golgi membranes  

PubMed Central

Recruitment of the Golgi-specific AP-1 adaptor complex onto Golgi membranes is thought to be a prerequisite for clathrin coat assembly on the TGN. We have used an in vitro assay to examine the translocation of cytosolic AP-1 onto purified Golgi membranes. Association of AP-1 with the membranes required GTP or GTP analogues and was inhibited by the fungal metabolite, brefeldin A. In the presence of GTP gamma S, binding of AP-1 to Golgi membranes was strictly dependent on the concentration of cytosol added to the assay. AP-1 recruitment was also found to be temperature dependent, and relatively rapid at 37 degrees C, following a lag period of 3 to 4 min. Using only an adaptor-enriched fraction from cytosol, purified myristoylated ARF1, and Golgi membranes, the GTP gamma S-dependent recruitment of AP-1 could be reconstituted. Our results show that the association of the AP-1 complex with Golgi membranes, like the coatomer complex, requires ARF, which accounts for the sensitivity of both to brefeldin A. In addition, they provide the basis for a model for the early biochemical events that lead to clathrin-coated vesicle formation on the TGN.

1993-01-01

259

Abnormal expression of transcription factor AP-2? in pathologic placentas*  

PubMed Central

Summary Recent studies from our laboratory have indicated that the transcription factor AP-2? plays a critical role in the differentiation of human villous cytotrophoblast cells (CTB) to syncytiotrophoblast cells (STB). However, little is known about the expression of AP-2? in placentas from pathologic pregnancies. This study compares the expression of AP-2? in placentas from high-risk pregnancies to gestational age-matched controls. Paracentral sections from grossly unremarkable areas of 10 placentas from each group of pregnancies complicated by mild preeclampsia (PE), severe PE, diabetes mellitus (DM), chronic hypertension (HTN), fetal growth restriction (FGR) and 10 control cases of placentas from normal pregnancies matched for gestational age (CG) were double immunostained for AP-2? and E-cadherin. The total numbers of CTB and STB and the numbers of AP-2? positive and negative nuclei in both of these cell types were counted by two pathologists blinded to disease status, in ten representative 40x fields (HPF) for each placenta. Abnormal placental maturation in most of pathologic pregnancies was evidenced by a 1.5–1.7-fold lower STB to CTB ratio. AP-2? expression in STB was lower in mild PE, DM, HTN and FGR (p<0.0001 in each instance) and was higher by 2-fold in severe PE, though this increase was not statistically significant (p=0.3). Since AP-2? has been shown to be critical for villous CTB differentiation, our findings suggest that abnormalities in the AP-2? cascade of transcription factors and/or signaling molecules may contribute to the pathogenesis of the abnormal maturation in placentas in certain types of high-risk pregnancies. The different pattern of AP-2? expression in mild and severe PE clearly suggests that these conditions may have two independent pathogenic mechanisms.

Sheridan, Rachel M.; Stanek, Jerzy; Khoury, Jane; Handwerger, Stuart

2012-01-01

260

Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes.  

PubMed

Cell types that generate unique lysosome-related organelles (LROs), such as melanosomes in melanocytes, populate nascent LROs with cargoes that are diverted from endosomes. Cargo sorting toward melanosomes correlates with binding via cytoplasmically exposed sorting signals to either heterotetrameric adaptor AP-1 or AP-3. Some cargoes bind both adaptors, but the relative contribution of each adaptor to cargo recognition and their functional interactions with other effectors during transport to melanosomes are not clear. Here we exploit targeted mutagenesis of the acidic dileucine-based sorting signal in the pigment cell-specific protein OCA2 to dissect the relative roles of AP-1 and AP-3 in transport to melanosomes. We show that binding to AP-1 or AP-3 depends on the primary sequence of the signal and not its position within the cytoplasmic domain. Mutants that preferentially bound either AP-1 or AP-3 each trafficked toward melanosomes and functionally complemented OCA2 deficiency, but AP-3 binding was necessary for steady-state melanosome localization. Unlike tyrosinase, which also engages AP-3 for optimal melanosomal delivery, both AP-1- and AP-3-favoring OCA2 variants required BLOC-1 for melanosomal transport. These data provide evidence for distinct roles of AP-1 and AP-3 in OCA2 transport to melanosomes and indicate that BLOC-1 can cooperate with either adaptor during cargo sorting to LROs. PMID:22718909

Sitaram, Anand; Dennis, Megan K; Chaudhuri, Rittik; De Jesus-Rojas, Wilfredo; Tenza, Danièle; Setty, Subba Rao Gangi; Wood, Christopher S; Sviderskaya, Elena V; Bennett, Dorothy C; Raposo, Graça; Bonifacino, Juan S; Marks, Michael S

2012-08-01

261

E6AP facilitates efficient transcription at estrogen responsive promoters through recruitment of chromatin modifiers  

Microsoft Academic Search

E6-AP is a known coactivator of the estrogen receptor alpha (ER?), however the coactivation mechanism of E6-AP is not clear. This work was undertaken to elucidate the coactivation mechanism of E6-AP. In order to examine the role of E6-AP in ER? signaling, we knocked-down the expression of E6-AP and examined the transactivation functions of ER?. Knockdown of E6-AP showed reduced

Heath W. Catoe; Zafar Nawaz

2011-01-01

262

Direct drive digital servo press with high parallel control  

NASA Astrophysics Data System (ADS)

Direct drive digital servo press has been developed as the university-industry joint research and development since 1998. On the basis of this result, 4-axes direct drive digital servo press has been developed and in the market on April of 2002. This servo press is composed of 1 slide supported by 4 ball screws and each axis has linearscale measuring the position of each axis with high accuracy less than ?m order level. Each axis is controlled independently by servo motor and feedback system. This system can keep high level parallelism and high accuracy even with high eccentric load. Furthermore the 'full stroke full power' is obtained by using ball screws. Using these features, new various types of press forming and stamping have been obtained by development and production. The new stamping and forming methods are introduced and 'manufacturing' need strategy of press forming with high added value and also the future direction of press forming are also introduced.

Murata, Chikara; Yabe, Jun; Endou, Junichi; Hasegawa, Kiyoshi

2013-12-01

263

Aquatox (Release 2) Modeling Environmental Fate and Ecological Effects in Aquatic Ecosystems. Volume 2: Technical Documentation.  

National Technical Information Service (NTIS)

New approaches and tools, including appropriate technical guidance documents, are needed to facilitate ecosystem analyses of watersheds as required by the Clean Water Act. In particular, there is a pressing need for refinement and release of an ecological...

2004-01-01

264

AQUATOX (Release 2) Modeling Environmental Fate and Ecological Effects in Aquatic Ecosystems. Volume 1: User's Manual.  

National Technical Information Service (NTIS)

New approaches and tools, including appropriate technical guidance documents, are needed to facilitate ecosystem analyses of watersheds as required by the Clean Water Act. In particular, there is a pressing need for refinement and release of an ecological...

R. A. Park J. S. Clough M. C. Wellman

2004-01-01

265

30. BUILDING NO. 527, DEHYDRATING PRESSES, LOOKING SOUTH. ALUMINUM NARROWGUAGE ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

30. BUILDING NO. 527, DEHYDRATING PRESSES, LOOKING SOUTH. ALUMINUM NARROW-GUAGE GONDOLA CAR IN LEFT BACKGROUND BROUGHT MOISTENED GUN COTTON FROM REST HOUSE (BUILDING NO. 320-B) IN CANS. (ONE OF THESE CANS IS ON UNLOADING PLATFORM RUNNING BESIDE PRESSES). CONTENTS OF CANS WERE UNLOADED INTO PRESSES BY HAND. - Picatinny Arsenal, 500 Area, Powder Factory & Power House, State Route 15 near I-80, Dover, Morris County, NJ

266

Tune measurement in the APS ring  

SciTech Connect

The APS system will contain three rings. The first is a positron accumulator ring (PAR). Its function is to coalesce 24, 30-ns-long positron bunches into one 290-ps bunch. The second is the injector synchrotron (IS). It accelerates the 450-MeV positron bunches to 7 Gev for injection into the storage ring (SR). Betatron and synchrotron motion frequently occurs in circular machines, without any deliberate excitation. However, the amplitudes of this motion cannot be predicted. Therefore, it is desirable to have controlled ways to excite these modes. Two types of devices will be used to excite the beam. One will be a magnetic kicker or bumper. All rings already have these devices planned for the horizontal direction for injecting and extracting beams. Some of these magnets will be used for exiting horizontal betatron motion. In the storage ring, a special kicker will be installed to produce up to 1 mm amplitude motion in the vertical direction. Two 8.4-in striplines (SL) (1/4 wavelength at 352 MHz) will be installed on all rings. One stripline in each ring will be used to drive all three tunes, and the other stripline will be used as a pickup. In the PAR and IS, the pickup stripline will be in a dispersive region. This will allow observation of both betatron and synchrotron motions. In the SR, the stripline will be in a nondispersive region because it is not practical to install it in a dispersive region. To do synchrotron tune measurements in the SR, one of the button BPMs located in a dispersive region will be used. To minimize development effort, as much of the BPM system electronics as possible will be used in the tune measurement system. The BPM electronics uses the AMP/PM conversion technique. This system operates at 352 MHz. Thus, tune measurement components were also designed to operate at 352 MHz.

Sellyey, W.; Kahana, E.; Wang, X.

1993-07-01

267

45-Day safety screening report for grab samples from Tank 241-AP-107  

SciTech Connect

Three samples; 107-AP-1C, 107-AP-2c and 107-AP-3C; were received at 222-S Laboratory for analysis of DSC, TGA and visual appearance. Four additional samples; 107-AP-1D, 107-AP-2D, 107-AP-3D and 107-AP-6; were received for visual appearance only. No results exceeded the safety screen notification criteria. This report compiles the analytical results. Tank 241-AP-107 is a double-shell tank which is not on any of the four Watch Lists.

Miller, G.L.

1995-03-08

268

Free Press: Beginner's Guide to Media Reform  

NSDL National Science Digital Library

Started in 2002 by author and professor Robert W. McChesney, the Free Press website is a clearinghouse of online material about the U.S. media reform movement. Some of the highlights of the site include profiles of all the organizations active in media reform, a detailed Learn About Media section with annotated background information, and original editorial content. One section that visitors will definitely want to take a close look at is the Media Policy area. Here users can receive current news information about the debates over media ownership as reflected by policy making decisions within the FCC, and also throughout the United States, and across the globe. The section dedicated to organizations is quite well-developed, and allows visitors to learn about various specific organizations interested in media reform, and how they may become involved with their work.

Mcchesney, Robert W.

269

Fracturing Demonstration using a Hydraulic Press  

NSDL National Science Digital Library

To prepare for the demonstration students are assigned homework problems dealing with brittle deformation in which they must plot Mohr diagrams and determine shear plane orientations and Coulomb coefficients. In class we examine an undeformed core of Yazoo clay (Eocene) taken from a test site on campus. The core is then uniaxially compressed using a hydraulic press. The students are then asked to observe and describe the development of shear fractures (including conjugate shear surfaces) and measure their orientations. In addition, they are asked to speculate on the development of extension fractures that develop during unloading. The fracture data are then used to estimate the Coulomb coefficient for the Yazoo clay sample and comparisons are made to values obtained from samples of differing lithologies. We wrap up with a class discussion summarizing observations from the fracture demonstration.

Harris, James B.

270

Blue Heron Press Collection: Artists' Books  

NSDL National Science Digital Library

The Blue Heron Press is based in Avoca, Nebraska, and over the past several decades they have published a number of exquisite chapbooks and illustrated works. Recently, the University of Nebraska Digital Collections group placed a number of their more recent publications online here. The works include some elaborate pieces that utilize wooden covers with leather spine wraps, and visitors can search the collection for various works. There are a number of "alphabet" themed books that contain colorful images and creative renderings of these 26 letters. Visitors are welcome to view the images in high resolution, and they can also zoom in and out to get a finer appreciation for all of the artistic details.

271

Read Recently Accepted Articles with Papers in Press  

NASA Astrophysics Data System (ADS)

Starting today, AGU journal articles are available within days of acceptance. With the introduction of Papers in Press, online subscribers can now access the PDF files of accepted manuscripts prior to copyediting and formatting. Articles at this stage are considered ``in press'' and are citable with the DOI for future linking. Each journal has its own list of Papers in Press updated daily; these article listings can be sorted by first author or by date of acceptance. Navigation to Papers in Press will be on the top page of each journal under Access.

2007-04-01

272

Dynamics of mat consolidation during pressing: what we've learned with our in-press radiation system for pressing wood composites  

NASA Astrophysics Data System (ADS)

We have designed a radiation-based system for density measurement of wood composites during pressing. During pressing, heat and mass transfer, consolidation speed and mat characteristics interact to produce a density distribution in the mat that is typified by high surface density and low core density. Measuring density of the wood mat during consolidation is a key parameter for understanding subsequent product performance. The system provides for density measurement at three horizontal planes in the wood mat, at positions of 25 percent, 50 percent, and 75 percent of the mat thickness at any time during the press cycle. The system incorporates three cesium sources and electronic detection equipment, collimated to move in concert with the up-acting press platen. Radiation count data taken at eight counts per second is converted to density. Press position and time are simultaneously recorded with the count data. Experimentation with the system has included radiation measurements in aspen and pine wood mats, incorporating different rates of press closure and furnish moisture content; both variables known to influence formation of the density distribution in the mat. Results are presented that depict density changes in the mat during pressing.

Winistorfer, Paul M.; Moschler, William W.

1996-11-01

273

Mechanism of action of the endo-(1-->3)-alpha-glucanase MutAp from the mycoparasitic fungus Trichoderma harzianum.  

PubMed

(1-->3)-alpha-glucanases catalyze the hydrolysis of fungal cell wall (1-->3)-alpha-glucan, and function during cell division of yeasts containing this cell wall component or act in mycoparasitic processes. Here, we characterize the mechanism of action of the (1-->3)-alpha-glucanase MutAp from the mycoparasitic fungus Trichoderma harzianum. We observed that MutAp releases predominantly beta-glucose upon hydrolysis of crystalline (1-->3)-alpha-glucan, indicating inversion of the anomeric configuration. After having identified (1-->3)-alpha-glucan tetrasaccharide as the minimal substrate for MutAp, we showed that reduced (1-->3)-alpha-glucan pentasaccharide is cleaved into a trisaccharide and a reduced disaccharide, demonstrating that MutAp displays endo-hydrolytic activity. We propose a model for the catalytic mechanism of MutAp, whereby the enzyme breaks an intrachain glycosidic linkage of (1-->3)-alpha-glucan, and then continues its hydrolysis towards the non-reducing end by releasing beta-glucose residues in a processive manner. PMID:16780840

Grün, Christian H; Dekker, Nick; Nieuwland, Alexander A; Klis, Frans M; Kamerling, Johannis P; Vliegenthart, Johannes F G; Hochstenbach, Frans

2006-07-10

274

An improved model for the combustion of AP composite propellants  

NASA Technical Reports Server (NTRS)

This paper presents several improvements to the BDP model of steady-state burning of AP composite solid propellants. The Price-Boggs-Derr model of AP monopropellant burning is incorporated to represent the AP. A separate energy equation is written for the binder to permit a different surface temperature from the AP; this includes an analysis of the sharing of primary diffusion flame energy, and correction of a BDP model inconsistency in treating the binder regression rate. A method for assembling component contributions to calculate the burning rates of multimodal propellants is also presented. Results are shown in the form of representative burning rate curves, comparisons with data, and calculated internal details of interest. Ideas for future work are discussed in an Appendix.

Cohen, N. S.; Strand, L. D.

1981-01-01

275

Ground vibration model studies for APS storage ring.  

National Technical Information Service (NTIS)

An analytical ground vibration model is developed for study of the vibration effects on the beam motion in the Advanced Photon Source (APS) storage ring. The different physical parameters associated with the wave characteristics and the vibration modes ne...

R. K. Koul

1994-01-01

276

Revisions to Emission Factors for AP-42 Organic Source Categories.  

National Technical Information Service (NTIS)

This document contains the text, as revised or originally written, of several sections prepared for inclusion in AP-42, 'Compilation of Air Pollutant Emission Factors.' Each section, or chapter of this document, includes: a description of the process, a p...

1978-01-01

277

QCD on the Massively Parallel Computer AP1000  

NASA Astrophysics Data System (ADS)

We present the QCD-TARO program of calculations which uses the parallel computer AP1000 of Fujitsu. We discuss the results on scaling, correlation times and hadronic spectrum, some aspects of the implementation and the future prospects.

Akemi, K.; Fujisaki, M.; Okuda, M.; Tago, Y.; Hashimoto, T.; Hioki, S.; Miyamura, O.; Takaishi, T.; Nakamura, A.; de Forcrand, Ph.; Hege, C.; Stamatescu, I. O.

278

Exercise Physiology-Fisiologia del Ejercicio - 2012 APS Video Contest  

NSDL National Science Digital Library

The Viewer's Choice award-winning video from the 2012 APS Video Contest. This video, which is recorded in english with spanish subtitles, describes cardiovasuclar adaptations that occur during exercise.

Facundo Mendes Garrido Abregu (Universidad de Buenos Aires); Sofia Aguirre (Universidad de Buenos Aires)

2012-05-02

279

Regional differences in the effects of isoflurane on neurotransmitter release.  

PubMed

Stimulus evoked neurotransmitter release requires that Na(+) channel-dependent nerve terminal depolarization be transduced into synaptic vesicle exocytosis. Inhaled anesthetics block presynaptic Na(+) channels and selectively inhibit glutamate over GABA release from isolated nerve terminals, indicating mechanistic differences between excitatory and inhibitory transmitter release. We compared the effects of isoflurane on depolarization-evoked [(3)H]glutamate and [(14)C]GABA release from isolated nerve terminals prepared from four regions of rat CNS evoked by 4-aminopyridine (4AP), veratridine (VTD), or elevated K(+). These mechanistically distinct secretegogues distinguished between Na(+) channel- and/or Ca(2+) channel-mediated presynaptic effects. Isoflurane completely inhibited total 4AP-evoked glutamate release (IC(50) = 0.42 ± 0.03 mM) more potently than GABA release (IC(50) = 0.56 ± 0.02 mM) from cerebral cortex (1.3-fold greater potency), hippocampus and striatum, but inhibited glutamate and GABA release from spinal cord terminals equipotently. Na(+) channel-specific VTD-evoked glutamate release from cortex was also significantly more sensitive to inhibition by isoflurane than was GABA release. Na(+) channel-independent K(+)-evoked release was insensitive to isoflurane at clinical concentrations in all four regions, consistent with a target upstream of Ca(2+) entry. Isoflurane inhibited Na(+) channel-mediated (tetrodotoxin-sensitive) 4AP-evoked glutamate release (IC(50) = 0.30 ± 0.03 mM) more potently than GABA release (IC(50) = 0.67 ± 0.04 mM) from cortex (2.2-fold greater potency). The magnitude of inhibition of Na(+) channel-mediated 4AP-evoked release by a single clinical concentration of isoflurane (0.35 mM) varied by region and transmitter: Inhibition of glutamate release from spinal cord was greater than from the three brain regions and greater than GABA release for each CNS region. These findings indicate that isoflurane selectively inhibits glutamate release compared to GABA release via Na(+) channel-mediated transduction in the four CNS regions tested, and that differences in presynaptic Na(+) channel involvement determine differences in anesthetic pharmacology. PMID:21651920

Westphalen, Robert I; Kwak, No-Bong; Daniels, Keir; Hemmings, Hugh C

2011-09-01

280

Effects of press closing time on mat consolidation behavior during hot pressing and on linear expansion of particleboard  

Microsoft Academic Search

Mat consolidation behavior was investigated at various press closing times (PCTs) using hinoki (Japanese cypress) particle\\u000a mats. The temperature in the core layer of the mat, press pressure, and platen distance were measured. At the plateau stage\\u000a during hot pressing, the core temperature decreased with increasing PCT. The core temperature did not increase before the\\u000a platen distance equaled the target

Kohta Miyamoto; Shigehiko Suzuki; Takayoshi Inagaki; Ritsuo Iwata

2002-01-01

281

Magnetic fields in Ap\\/Bp stars (Auriere+, 2007)  

Microsoft Academic Search

We have investigated a sample of 28 well-known spectroscopically-identified magnetic Ap\\/Bp stars, with weak, poorly-determined or previously undetected magnetic fields. The aim of this study is to explore the weak part of the magnetic field distribution of Ap\\/Bp stars. Using the MuSiCoS and NARVAL spectropolarimeters at Telescope Bernard Lyot (Observatoire du Pic du Midi, France) and the cross-correlation technique Least

M. Auriere; G. A. Wade; J. Silvester; F. Lignieres; S. Bagnulo; K. Bale; B. Dintrans; J. F. Donati; C. P. Folsom; M. Gruberbauer; A. Hui Bon Hoa; S. Jeffers; N. Johnson; J. D. Landstreet; A. Lebre; T. Lueftinger; S. Marsden; D. Mouillet; S. Naseri; F. Paletou; P. Petit; J. Power; F. Rincon; S. Strasser; N. Toque

2007-01-01

282

6LoWPAN Compressed DTLS for CoAP  

Microsoft Academic Search

Real deployments of the IoT require security. CoAP is being standardized as an application layer protocol for the Internet of Things (IoT). CoAP proposes to use DTLS to provide end-to-end security to protect the IoT. DTLS is a heavyweight protocol and its headers are too long to fit in a single IEEE802.15.4 MTU. 6LoWPAN provides header compression mechanisms to reduce

Shahid Raza; Daniele Trabalza; Thiemo Voigt

2012-01-01

283

Early-Phase Spectra of ``Hypernova'' SN 2002ap  

Microsoft Academic Search

The spectral evolution of the peculiar Type Ic supernova (SN) 2002ap during the first 40 days is presented. The spectra display very broad absorption features, which are typical of ``hypernovae.'' The maximum expansion velocity measured on the earliest spectra exceeds 3×104 km s-1. The spectrum of SN 2002ap at the epoch of maximum brightness resembles that of SN 1997ef more

K. Kinugasa; H. Kawakita; K. Ayani; T. Kawabata; H. Yamaoka; J. S. Deng; P. A. Mazzali; K. Maeda; K. Nomoto

2002-01-01

284

BVRI photometry of the type Ic Hypernova SN 2002ap  

Microsoft Academic Search

The BVRI photometric observations of type-Ic SN 2002ap at maximum and during the fast-decline phase after maximum are presented. We used our BVRI photometry and published data in order to compute the magnitudes and dates of peak brightness. The absolute magnitude at maximum brightness of SN 2002ap shows that it was fainter than SN 1998bw, but similar to SN 1997ef.

L. M. Cook; E. V. Katkova; N. A. Sokolov; I. S. Guseva

2002-01-01

285

Thermal Decomposition Characteristics of Orthorhombic Ammonium Perchlorate (o-AP)  

SciTech Connect

Preliminary STMBMS and SEM results of the thermal decomposition of AP in the orthorhombic phase are presented. The overall decomposition is shown to be complex and controlled by both physical and chemical processes. The data show that the physical and chemical processes can be probed and characterized utilizing SEM and STMBMS. The overall decomposition is characterized by three distinguishing features: an induction period, and accelerator period and a deceleratory period. The major decomposition event occurs in the subsurface of the AP particles and propagates towards the center of the particle with time. The amount of total decomposition is dependent upon particle size and increases from 23% for {approximately}50{micro}m-diameter AP to 33% for {approximately}200{micro}m-diameter AP. A conceptual model of the physical processes is presented. Insight into the chemical processes is provided by the gas formation rates that are measured for the gaseous products. To our knowledge, this is the first presentation of data showing that the chemical and physical decomposition processes can be identified from one another, probed and characterized at the level that is required to better understand the thermal decomposition behavior of AP. Future work is planned with the goal of obtaining data that can be used to develop a mathematical description for the thermal decomposition of o-AP.

Behrens, R.; Minier, L.

1999-03-01

286

NF-kappaB and AP1 connection: mechanism of NF-kappaB-dependent regulation of AP1 activity  

Microsoft Academic Search

Nuclear factor kappaB (NF-kappaB) and activator protein 1 (AP-1) transcription factors regulate many important biological and pathological processes. Activation of NF-kappaB is regulated by the inducible phosphorylation of NF-kappaB inhibitor IkappaB by IkappaB kinase. In contrast, Fos, a key component of AP-1, is primarily transcriptionally regulated by serum responsive factors (SRFs) and ternary complex factors (TCFs). Despite these different regulatory

Shuichi Fujioka; Jiangong Niu; Christian Schmidt; Guido M Sclabas; Bailu Peng; Tadashi Uwagawa; Zhongkui Li; Douglas B Evans; James L Abbruzzese; Paul J Chiao

2004-01-01

287

Comparison of ceramic waste forms produced by hot uniaxial pressing and by cold pressing and sintering  

SciTech Connect

Synroc C waste form specimens prepared using the Australian-developed technology are uniaxially pressed in stainless steel bellows at 1200{degrees}C and 20MPa. This produces a material with high chemical and physical durability and with the radioactivity enclosed inside both the waste form and the bellows. An alternative method of producing the ceramic product is to use cold pressing of pellets followed by reactive sintering to provide densification and mineralization. Depending on the scale of waste form preparation required and on the activity level and nature of the waste streams, the cold press and sinter method may have advantages. To evaluate the effects of production method on waste form characteristics, especially resistance to dissolution or leaching of waste elements, we have prepared two simulated waste samples for evaluation. Both samples were prepared from liquid precursor materials (alkoxides, nitrates, and colloidal silica) and then doped with waste elements. The precursor material in each case corresponded to a basic phase assemblage of 60% zirconolite, 15% nepheline, 10% spinel, 10% perovskite, and 5% rutile. One sample was doped with 25% by weight of U; the other with 10% by weight each of U and Gd. Each sample was calcined at 750{degrees}C for 1 hr. in a 3.5% H{sub 2} in N{sub 2} atmosphere. Then one portion of each sample was hot pressed at temperatures ranging from 1120 to 1250{degrees}C and 20MPa pressure in steel bellows. A separate portion of each sample was formed into pellets, cold pressed, and sintered in various atmospheres at 1200{degrees}C to produce final products about 2/3 cm in diameter. Samples were then examined to determine density of the product, grain sizes of the phases, phase assemblage, and the location of the U and Gd in the final phases. Density data indicate that sintering gives good results provided that the samples are held at 200{degrees}C for long enough to allow trapped gases to escape.

Oversby, V.M. [Lawrence Livermore National Lab., CA (United States); Vance, E.R. [Australian Nuclear Science and Technology Organization, Lucas Heights (Australia)

1994-09-01

288

A nonmagnetic uniaxial press with a tiltable piston  

Microsoft Academic Search

The press has an oil-driven piston which is free to tilt, the oil being retained by a rubber diaphragm rather than by O rings. It consistently produced less than 15% difference in strain between opposite sides of a uniform cylindrical sample. Two presses of this design were used in extensive experiments on the effect of uniaxial compression on the magnetization

J. P. Hodych

1973-01-01

289

A die pressing test for the estimation of agglomerate strength  

Microsoft Academic Search

A die pressing test was developed for quick and inexpensive estimation of the agglomerate strength of ceramic powders. The critical nominal pressure (p[sub c]) at which contact areas between agglomerates start to increase rapidly was found from the relationship between change in sample height and applied pressure in uniaxial single-ended die pressing. A quantitative microscopic method was used for measuring

Jin-Hua Song; Julian R. G. Evans

1994-01-01

290

The Role of the Black Press during the "Great Migration."  

ERIC Educational Resources Information Center

Between the years of 1916 and 1918 southern blacks began populating the urban centers of the north in a movement known as the "Great Migration." This movement was significant to the development of the black press, for it was during this period that the black press became a protest organ and rose to its greatest level of prominence and influence.…

Jones, Felecia G.

291

Modelling of Vertical Density Profile of MDF in Hot Pressing  

Microsoft Academic Search

The hot pressing operation is one of the most important operations in medium density fibreboard (MDF) manufacture. Complicated dynamic interactions occur during pressing, including heat transfer, moisture movement, development of gas pressure, internal stress development and relaxation, wood consolidation, resin curing, bonding between particles and eventual development of a nonuniform density distribution through the panel thickness. Consequently the mat experiences

Arun Gupta; Patrick J Jordan; Shusheng Pang

292

Massachusetts Adviser Urges a National Student Press Rights Drive.  

ERIC Educational Resources Information Center

Argues that students are being trained to believe that censorship of the press is a good idea. Shows, using two examples dealing with teenage pregnancies and gangs, how students can bring about real change in their school climate through their school newspaper--but only if it is a free press controlled by students, not the administration. (SR)

Proudfoot, Harry

2000-01-01

293

First Amendment Speech and Press Theory: Preferred Position Postulate Reexamined.  

ERIC Educational Resources Information Center

If the United States Supreme Court is to exercise its historic role as guardian of the fundamental freedoms flowing from the speech and press clauses of the first amendment, it is imperative that those basic freedoms be placed in a preferred position. The preferred position doctrine provides adequate safeguards for both speech and press guarantees…

Stonecipher, Harry W.

294

The Operationalization of the Needs-Press Model: A Critique.  

ERIC Educational Resources Information Center

The needs-press model, as operationalized by the Stern Activities Index (AI) and the Organizational Climate Index (OCI), was examined for its usefulness in evaluating and measuring organizational climate in a school setting. According to the model, needs represents personality and press represents the environment. This research was designed to…

May, Carolyn S.

295

Fair Press or Trial Prejudice?: Perceptions of Criminal Defendants.  

ERIC Educational Resources Information Center

Examines criminal defendants' perceptions of the free press/fair trial issue with respect to perceived influences of media coverage on the disposition of criminal cases and the outcome of criminal trials. Concludes that the press' influence on trials is generally perceived as minimal and fair. (MM)

Sherard, Regina Ganelle

1987-01-01

296

STS-5 crew during pre-flight press briefing  

NASA Technical Reports Server (NTRS)

STS-5 crew during pre-flight press briefing. Mission Specialist Joseph P. Allen toys with a small space shuttle model while the rest of the STS-5 crew shares a laugh during the October 6 pre-flight press conference. The others are Astronauts Vance D. Brand, right, commander; Robert F. Overmyer, second right, pilot; and William B. Lenoir, mission specialist.

1982-01-01

297

Temporalities and environmental reporting: press news on eutrophication in Finland  

Microsoft Academic Search

Media coverage is increasingly setting the agenda for environmental policy, even though the media has no formal role in policy making. This article explores water eutrophication in the Finnish press. The focus is on the temporal variations presented in the press articles. The DPSIR framework describing the Driving forces, Pressures, State, Impacts, and Responses, and the concept of timescape are

Jari M. Lyytimäki

2007-01-01

298

6. Interior, first floor front room. View of pressed metal ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

6. Interior, first floor front room. View of pressed metal ceiling visible through opening in dropped ceiling. (Below the pressed metal ceiling are three wooden joists, two electrical wires and the edges of the dropped ceiling where a panel had been removed). - Ferree Building, 417 Ninth Street, Northwest, Washington, District of Columbia, DC

299

The Press and NEPA: The Case of the Missing Agenda.  

ERIC Educational Resources Information Center

Surveys media coverage of the 1969 National Environmental Policy Act (NEPA), concluding that there was a general lack of press attention to NEPA and that Congress constructed its own social reality with respect to NEPA in the absence of an agenda-setting role by the press. (GT)

Schoenfeld, A. Clay

1979-01-01

300

A simple pressing route to closed-cell microcellular ceramics  

Microsoft Academic Search

A simple pressing process using a polysiloxane and expanded microspheres for fabricating closed-cell microcellular ceramics is demonstrated. The strategy for making the microcellular ceramics involves: (i) forming preceramic foams using a mixture of preceramic polymer and expanded microspheres by pressing, (ii) cross-linking the formed body, and (iii) transforming the body into microcellular ceramics by pyrolysis. By controlling the microsphere content,

Young-Wook Kim; Yong-Jae Jin; Yong-Seong Chun; In-Hyuck Song; Hai-Doo Kim

2005-01-01

301

Packaging the News; A Critical Survey of Press, Radio, TV.  

ERIC Educational Resources Information Center

In the 19th century, the American press was characterized by a profusion of independent newspapers, quick to criticize the government. In this century, the press and the other mass media have become owned by relatively few proprietors, all trumpeting the same capitalistic, government line. Even though they criticize the government occasionally,…

Aronson, James

302

The press and the political restructuring of Ethiopia  

Microsoft Academic Search

Divisive debates on what constitutes the Ethiopian nation, how the state should be structured and how power should be devolved, have dominated Ethiopia's private press since the ruling party, the Ethiopian Peoples Revolutionary Democratic Front (EPRDF), came to power. The press has served as both a mirror reflecting these issues and a space for literate elites to engage in political

Nicole Stremlau

2011-01-01

303

Korean and Japanese Press: A Study in Crisis.  

ERIC Educational Resources Information Center

During a time of crisis, it is instructive to examine the national press of Japan and Korea, two economic allies that view each other with suspicion. The Japanese press is relatively free and liberal-oriented on the domestic scene but is closely aligned with big business and government with regard to international concerns. The South Korean…

Ruidl, Richard A.

304

Dewatering press liquor derived from orange production by forward osmosis  

Microsoft Academic Search

In this investigation, a forward osmosis (FO) dewatering process is evaluated as an alternative for dewatering orange peel press liquor. The press liquor is concentrated by removing water via osmosis into a concentrated “draw solution” across a polymeric cellulose acetate membrane. For this investigation, the draw solution consisted of sodium chloride at two different concentrations (2M and 4M). These draw

Esperanza M. Garcia-Castello; Jeffrey R. McCutcheon

2011-01-01

305

The effect of hot isostatic pressing on cast aluminum  

NASA Astrophysics Data System (ADS)

Aluminum-silicon alloys are the most important commercial aluminum casting alloys, primarily because of their superior casting characteristics. This article discusses the effect of hot isostatic pressing on the mechanical properties of cast aluminum alloy A356. The effect of low-cost Densal hotisostatic pressing is also examined.

Lei, C. S. C.; Frazier, W. E.; Lee, E. W.

1997-11-01

306

State Free Expression Laws and Scholastic Press Censorship.  

ERIC Educational Resources Information Center

Surveys high school newspaper advisors, finding remarkably similar attitudes, in states with scholastic freedom of press laws and states without such laws, regarding scholastic press freedom, the way they exercise their duty in overseeing the newspaper, censorship and self-censorship, and controversy over newspaper content. Finds differences in…

Paxton, Mark; Dickson, Tom

2000-01-01

307

The American Press and the Holocaust. Classroom Focus.  

ERIC Educational Resources Information Center

Contends that U.S. press coverage of the destruction of the Jews during World War II was sidebar or ancillary at best. Argues that the press often buried significant information on inside pages. Presents a secondary level lesson plan with student objectives and step-by-step instructional objectives. (CFR)

Wieser, Paul

1995-01-01

308

Styles of Image Management During Crises: Justifying Press Censorship  

Microsoft Academic Search

Press freedom is crucial in times of national crisis such as rampant terrorism or war. But press freedom is likely to become a casualty at such times because of legitimate concerns about security for civilians and military personnel and because of fears of compromising the confidentiality of important public policies. What kinds of appeals do partisans and opponents of both

DORIS GRABER

2003-01-01

309

Experimenting with Houseplants: Publishing at Five University Presses.  

ERIC Educational Resources Information Center

Discusses the pros and cons of the increased willingness of university presses to include trade books within their lists. Describes an experiment in which the same manuscript dealing with a nonacademic subject was submitted for publication at five university presses. (JP)

Denham, Alice

1980-01-01

310

Parallelization of Rocket Engine Simulator Software (PRESS)  

NASA Technical Reports Server (NTRS)

Parallelization of Rocket Engine System Software (PRESS) project is part of a collaborative effort with Southern University at Baton Rouge (SUBR), University of West Florida (UWF), and Jackson State University (JSU). The second-year funding, which supports two graduate students enrolled in our new Master's program in Computer Science at Hampton University and the principal investigator, have been obtained for the period from October 19, 1996 through October 18, 1997. The key part of the interim report was new directions for the second year funding. This came about from discussions during Rocket Engine Numeric Simulator (RENS) project meeting in Pensacola on January 17-18, 1997. At that time, a software agreement between Hampton University and NASA Lewis Research Center had already been concluded. That agreement concerns off-NASA-site experimentation with PUMPDES/TURBDES software. Before this agreement, during the first year of the project, another large-scale FORTRAN-based software, Two-Dimensional Kinetics (TDK), was being used for translation to an object-oriented language and parallelization experiments. However, that package proved to be too complex and lacking sufficient documentation for effective translation effort to the object-oriented C + + source code. The focus, this time with better documented and more manageable PUMPDES/TURBDES package, was still on translation to C + + with design improvements. At the RENS Meeting, however, the new impetus for the RENS projects in general, and PRESS in particular, has shifted in two important ways. One was closer alignment with the work on Numerical Propulsion System Simulator (NPSS) through cooperation and collaboration with LERC ACLU organization. The other was to see whether and how NASA's various rocket design software can be run over local and intra nets without any radical efforts for redesign and translation into object-oriented source code. There were also suggestions that the Fortran based code be encapsulated in C + + code thereby facilitating reuse without undue development effort. The details are covered in the aforementioned section of the interim report filed on April 28, 1997.

Cezzar, Ruknet

1997-01-01

311

Development of Press-Coated, Floating-Pulsatile Drug Delivery of Lisinopril  

PubMed Central

Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor, primarily used for the treatment of hypertension, congestive heart failure, and heart attack. It belongs to BCS class III having a half-life of 12 hrs and 25% bioavailability. The purpose of the present work was to develop a press-coated, floating-pulsatile drug delivery system. The core tablet was formulated using the super-disintegrants crosprovidone and croscarmellose sodium. A press-coated tablet (barrier layer) contained the polymer carrageenan, xanthan gum, HPMC K4M, and HPMC K15M. The buoyant layer was optimized with HPMC K100M, sodium bicarbonate, and citric acid. The tablets were evaluated for physical characteristics, floating lag time, swelling index, FTIR, DSC, and in vitro and in vivo behavior. The 5% superdisintgrant showed good results. The FTIR and DSC study predicted no chemical interactions between the drug and excipients. The formulation containing xanthan gum showed drug retaining abilities, but failed to float. The tablet containing HPMC K15M showed a high swelling index. The lag time for the tablet coated with 200 mg carrageenan was 3±0.1 hrs with 99.99±1.5% drug release; with 140 mg HPMC K4M, the lag time was 3±0.1 hrs with 99.71±1.2% drug release; and with 120 mg HPMC K15M, the lag time was 3±0.2 hrs with 99.98±1.7% drug release. The release mechanism of the tablet followed the Korsmeyer-Peppas equation and a first-order release pattern. Floating and lag time behavior have shown good in vitro and in vivo correlations.

Jagdale, Swati C.; Suryawanshi, Vishnu M.; Pandya, Sudhir V.; Kuchekar, Bhanudas S.; Chabukswar, Aniruddha R.

2014-01-01

312

Development of press-coated, floating-pulsatile drug delivery of lisinopril.  

PubMed

Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor, primarily used for the treatment of hypertension, congestive heart failure, and heart attack. It belongs to BCS class III having a half-life of 12 hrs and 25% bioavailability. The purpose of the present work was to develop a press-coated, floating-pulsatile drug delivery system. The core tablet was formulated using the super-disintegrants crosprovidone and croscarmellose sodium. A press-coated tablet (barrier layer) contained the polymer carrageenan, xanthan gum, HPMC K4M, and HPMC K15M. The buoyant layer was optimized with HPMC K100M, sodium bicarbonate, and citric acid. The tablets were evaluated for physical characteristics, floating lag time, swelling index, FTIR, DSC, and in vitro and in vivo behavior. The 5% superdisintgrant showed good results. The FTIR and DSC study predicted no chemical interactions between the drug and excipients. The formulation containing xanthan gum showed drug retaining abilities, but failed to float. The tablet containing HPMC K15M showed a high swelling index. The lag time for the tablet coated with 200 mg carrageenan was 3±0.1 hrs with 99.99±1.5% drug release; with 140 mg HPMC K4M, the lag time was 3±0.1 hrs with 99.71±1.2% drug release; and with 120 mg HPMC K15M, the lag time was 3±0.2 hrs with 99.98±1.7% drug release. The release mechanism of the tablet followed the Korsmeyer-Peppas equation and a first-order release pattern. Floating and lag time behavior have shown good in vitro and in vivo correlations. PMID:24959410

Jagdale, Swati C; Suryawanshi, Vishnu M; Pandya, Sudhir V; Kuchekar, Bhanudas S; Chabukswar, Aniruddha R

2014-06-01

313

Toggle release  

NASA Technical Reports Server (NTRS)

The invention relates to a pyrotechnic actuated release mechanism which is mechanically two fault tolerant for effecting release. It is particularly well suited for releasably connecting structures to be used in the space environment or in other aerospace applications. The device comprises a fastener plate and fastener body, each attachable to either one of a pair of structures to be joined. The fastener plate and the body are fastenable by a toggle supported at one end on the fastener plate and mounted for universal pivotal movement thereon. At its other end, which is received in a central opening in the fastener body and adapted for limited pivotal movement therein, the toggle is restrained by three retractable latching pins. Each pin is individually retractable by combustion of a pyrotechnic charge. While retraction of all three pins releases the toggle, the fastener is mechanically two fault tolerant since the failure of any single or pair of the latch pins to retract results in an asymmetrical loading on the toggle and its pivotal movement to effect a release. An annular bolt is mounted on the fastener plate as a support for the socket mounting of the toggle whereby its selective axial movement provides a means for pre-loading the toggle.

Graves, Thomas Joseph (inventor); Yang, Robert Alexander (inventor); Brown, Christopher William (inventor)

1988-01-01

314

[The use of dried grape press cake in pig fattening].  

PubMed

In dried grape press cake the content of crude nutrients and ash, overall sugar, amino acids, alpha-tocopherol and gross energy was determined. In biological experiments with pigs (total of 109 animals) 10% of mixture A1 or SOL was replaced by the same amount of dried crushed grape press cake, without affecting negatively the weight gains and consumption of mixtures per unit of weight gain. Nutritional effects of grape press cake are a subject of discussion and comprise three factors: higher content of enrgy (fat and sugars) in mixtures containing press cake, anti-oxidation effect of press cake and the effect of tocopherols on the metabolism of basic nutrients. PMID:118573

Herzig, I; Tomová, M; Holub, A; Pleskac, Z

1979-12-01

315

STS-46 post flight press conference  

NASA Astrophysics Data System (ADS)

At a post flight press conference, the flight crew of the STS-46 mission (Cmdr. Loren Shriver, Pilot Andrew Allen, Mission Specialists Claude Nicollier (European Space Agency (ESA)), Marsha Ivins (Flight Engineer), Jeff Hoffman (Payload Commander), Franklin Chang-Dias, and Payload Specialist Franco Malerba (Italian Space Agency (ISA))) discussed their roles in and presented video footage, slides and still photographs of the different aspects of their mission. The primary objectives of the mission were the deployment of ESA's European Retrievable Carrier (EURECA) satellite and the joint NASA/ISA deployment and testing of the Tethered Satellite System (TSS). Secondary objectives included the IMAX Camera, the Limited Duration Space Environment Candidate Materials Exposure (LDVE), and the Pituitary Growth Hormone Cell Function (PHCF) experiments. Video footage of the EURECA and TSS deployment procedures are shown. Earth views were extensive and included Javanese volcanoes, Amazon basin forest ground fires, southern Mexico, southern Bolivian volcanoes, south-west Sudan and the Sahara Desert, and Melville Island, Australia. Questions from reporters and journalists from Johnson Space Center and Kennedy Space Center were discussed.

1992-08-01

316

STS-114: Discovery Post MMT Press Conference  

NASA Technical Reports Server (NTRS)

Bruce Buckingham of NASA Public Affairs hosted this press conference. Wayne Hill, Space Shuttle Deputy Program Manager; John Muratore, Shuttle Systems and Integration Manager; Mike Wetmore, Director for Shuttle Processing were present. Wayne started with a video from Shuttle Logistics Depot showing details of a point sensor box commonly named the black box. Work with the trouble shooting continues on a day to day basis, no definite launching date is set. John reports that they are in a mission support mode all over the country until the sensor problem is solved. Mike reports his team will complete scrub and securing tasks through the next day, restore the facility to its normal mode, and will start to a four day process of getting back to launch once trouble shooting is completed. Tanking test, thermal environment, problem identification, engine cut-off sensor problems, sensors, risk, design reviews, test and analysis, correlation of the problem with Columbia, are some of the topics covered with the News media.

2005-01-01

317

[Work disability in public press professions].  

PubMed

In this study more than 1,000 cases of long-term disability among members of the press and media were evaluated. Mental disorders were the main cause of disability in almost every fourth case. In women psychiatric illnesses were even more important. The most common diagnosis was that of a depressive disorder which accounted for more than half of all psychiatric cases. The causes of disability of other insurance systems such as the German social security scheme and the pension and disability plan for the medical profession were compared. Mental illnesses are the leading cause of disability in white collar workers and orthopaedic illnesses, especially disorders of the vertebral column, are the leading cause in blue collar workers, as one might have expected. In females mental disorders are even more common than in men whereas men tend to have more cardiovascular problems than women. In this study also some interesting features regarding disability caused by various illnesses after long-term follow-up were found. This opens unknown perspectives allowing new assessment of diseases and eventually will enable the actuary to price medical diagnoses for disability insurance. PMID:12242775

Akermann, S

2002-09-01

318

Transcription factor AP2 and monoaminergic functions in the central nervous system  

Microsoft Academic Search

Summary. In the central nervous system, transcription factor AP-2 family is one of the critical regulatory factors for neural gene expression and neuronal development. Several genes in the monoaminergic systems display AP-2 binding sites in regulatory regions. In addition, brainstem levels of transcription factor AP-2? and AP-2? are positively correlated to monoamine measures in rat forebrain, suggesting a regulatory role

M. Damberg

2005-01-01

319

EPICS release 3.11.6 specific documentation -- Release notes for EPICS 3.11.6  

SciTech Connect

These notes cover the following: (1) directions for switching to production APS release R3.11.6; (2) unbundling of channel access clients; (3) access security; (4) channel access additions; synchronous time support; and (5) description of major differences between R3.11.3 and R3.11.6 Also included is a list of new and/or updated documentation for the program.

NONE

1994-06-07

320

AP1 transcription factors in epidermal differentiation and skin cancer.  

PubMed

AP1 (jun/fos) transcription factors (c-jun, junB, junD, c-fos, FosB, Fra-1, and Fra-2) are key regulators of epidermal keratinocyte survival and differentiation and important drivers of cancer development. Understanding the role of these factors in epidermis is complicated by the fact that each protein is expressed, at different levels, in multiple cells layers in differentiating epidermis, and because AP1 transcription factors regulate competing processes (i.e., proliferation, apoptosis, and differentiation). Various in vivo genetic approaches have been used to study these proteins including targeted and conditional knockdown, overexpression, and expression of dominant-negative inactivating AP1 transcription factors in epidermis. Taken together, these studies suggest that individual AP1 transcription factors have different functions in the epidermis and in cancer development and that altering AP1 transcription factor function in the basal versus suprabasal layers differentially influences the epidermal differentiation response and disease and cancer development. PMID:23762562

Eckert, Richard L; Adhikary, Gautam; Young, Christina A; Jans, Ralph; Crish, James F; Xu, Wen; Rorke, Ellen A

2013-01-01

321

Toggle release  

NASA Technical Reports Server (NTRS)

A pyrotechnic actuated structural release device 10 which is mechanically two fault tolerant for release. The device 10 comprises a fastener plate 11 and fastener body 12, each attachable to a different one of a pair of structures to be joined. The fastener plate 11 and body 12 are fastenable by a toggle 13 supported at one end on the fastener plate and mounted for universal pivotal movement thereon. At its other end which is received in a central opening in the fastener body 12 and adapted for limited pivotal movement therein the toggle 13 is restrained by three retractable latching pins 61 symmetrically disposed in equiangular spacing about the axis of the toggle 13 and positionable in latching engagement with an end fitting on the toggle. Each pin 61 is individually retractable by combustion of a pyrotechnic charge 77, the expanding gases of which are applied to a pressure receiving face 67 on the latch pin 61 to effect its retraction from the toggle. While retraction of all three pins 62 releases the toggle, the fastener is mechanically two fault tolerant since the failure of any single one or pair of the latch pins to retract results in an asymmetrical loading on the toggle and its pivotal movement to effect a release. An annular bolt 18 is mounted on the fastener plate 11 as a support for the socket mounting 30, 37 of the toggle whereby its selective axial movement provides a means for preloading the toggle.

Graves, Thomas J. (Inventor); Yang, Robert A. (Inventor); Brown, Christopher W. (Inventor)

1989-01-01

322

Autosomal recessive spastic tetraplegia caused by AP4M1 and AP4B1 gene mutation: Expansion of the facial and neuroimaging features.  

PubMed

Adaptor protein complex-4 (AP4) is a component of intracellular transportation of proteins, which is thought to have a unique role in neurons. Recently, mutations affecting all four subunits of AP4 (AP4M1, AP4E1, AP4S1, and AP4B1) have been found to cause similar autosomal recessive phenotype consisting of tetraplegic cerebral palsy and intellectual disability. The aim of this study was analyzing AP4 genes in three new families with this phenotype, and discussing their clinical findings with an emphasis on neuroimaging and facial features. Using homozygosity mapping followed by whole-exome sequencing, we identified two novel homozygous mutations in AP4M1 and a homozygous deletion in AP4B1 in three pairs of siblings. Spastic tetraplegia, microcephaly, severe intellectual disability, limited speech, and stereotypic laughter were common findings in our patients. All patients also had similar facial features consisting of coarse and hypotonic face, bitemporal narrowing, bulbous nose with broad nasal ridge, and short philtrum which were not described in patients with AP4M1 and AP4B1 mutations previously. The patients presented here and previously with AP4M1, AP4B1, and AP4E1 mutations shared brain abnormalities including asymmetrical ventriculomegaly, thin splenium of the corpus callosum, and reduced white matter volume. The patients also had hippocampal globoid formation and thin hippocampus. In conclusion, disorders due to mutations in AP4 complex have similar neurological, facial, and cranial imaging findings. Thus, these four genes encoding AP4 subunits should be screened in patients with autosomal recessive spastic tetraplegic cerebral palsy, severe intellectual disability, and stereotypic laughter, especially with the described facial and cranial MRI features. © 2014 Wiley Periodicals, Inc. PMID:24700674

Tüysüz, Beyhan; Bilguvar, Kaya; Koçer, Naci; Yalç?nkaya, Cengiz; Ca?layan, Okay; Gül, Ece; Sahin, Sezgin; Comu, Sinan; Günel, Murat

2014-07-01

323

Hot pressing Nd-Fe-B HDDR powders  

SciTech Connect

Details of the important parameters for hot pressing isotropic Nd{sub 16}Fe{sub 76}B{sub 8} HDDR powders are presented. Optimum magnetic properties may be achieved over broad ranges of green compaction pressure and hot pressing temperature, time and pressure. Isotropic HDDR powders with lower Nd-contents (i.e., Nd{sub 14}Fe{sub 79}B{sub 7} and Nd{sub 13}Fe{sub 80.5}B{sub 6.5}) may also be hot pressed to full density to produce magnets with energy products {approximately} 100 kJ/m{sup 3} and some advantages of hot pressing the lower Nd-content compositions are stated. The cause of the enhanced values of remanence obtained for nominally isotropic hot pressed HDDR magnets is probably due to some alignment induced during hot pressing. The ease of hot pressing HDDR powder suggests this process is commercially viable, particularly as the HDDR powder production process has been estimated to be cheaper than that of the MQ powder.

Ragg, O.M.; Harris, I.R. [Univ. of Birmingham (United Kingdom). School of Metallurgy and Materials] [Univ. of Birmingham (United Kingdom). School of Metallurgy and Materials; Nagel, H. [NKE GmbH, Kamen Herens Werye (Germany)] [NKE GmbH, Kamen Herens Werye (Germany); Boehm, P. [Thyssen Magnettechnik GmbH, Dortmund (Germany)] [Thyssen Magnettechnik GmbH, Dortmund (Germany)

1996-09-01

324

Mutant AP endonuclease in patients with amyotrophic lateral sclerosis.  

PubMed

Among the more frequent oxidative DNA injuries is the formation of abasic sites (AP sites) resulting from removal of purine or pyrimidine bases, estimated to occur at a rate of 1 x 10(4)/genome/24 h. A defect in DNA repair at this level could account for the accumulation of mutations and subsequent genome instability. We have identified missense mutations in the APE gene coding for a multifunctional DNA repair enzyme, AP endonuclease in eight of 11 patients with amyotrophic lateral sclerosis (ALS) and familial ALS. These mutations could affect the repair of abasic sites leading to the accumulation of mutations in neurons, resulting in their degeneration and death. Our findings implicate mutated AP endonuclease in the pathogenesis of ALS. PMID:9507962

Olkowski, Z L

1998-01-26

325

Experience with the EPICS PV Gateway at the APS.  

SciTech Connect

The EPICS Process Variable Gateway has become a stable, high-performance application that provides access to process variables while minimizing the impact on critical Input-Output Controllers (IOCs) and implementing additional access security. The additional access security typically prevents write access but is highly configurable. The Advanced Photon Source (APS) currently uses 40 Gateways running on 11 workstations to provide access to the machine subnet from the offices and for the individual experimental teams. These include reverse Gateways that allow administration of all 40 APS Gateways from a single MEDM screen, even though the Gateways are running on separate networks. This administration includes starting, stopping, making and viewing reports, and viewing and editing access security files. There is one Gateway that provides process variable renaming. This paper provides an overview of the Gateways at the APS and describes the procedures that have been set up to use and administer them.

Evans, K. Jr.; Smith, M.; Accelerator Systems Division (APS)

2006-01-01

326

Material utilisation when depositing CdTe layers by inline AP-MOCVD  

NASA Astrophysics Data System (ADS)

A study was undertaken to assess the efficiency of precursors' usage during deposition of cadmium telluride (CdTe) layers via atmospheric pressure metal organic chemical vapour deposition (AP-MOCVD) for thin film photovoltaic solar cells. Precursors were released from a showerhead assembly normal to the glass substrate 0.7 mm thick (5×7.5 cm2) being deposited which was kept stationary or moved under the showerhead assembly, with speed of upto 2.25 cm/min. In order to estimate the effective precursor utilisation, the weight deposit (layer) was compared against the theoretical values calculated for ideal molar supply. The layer thickness, composition, morphology, and crystallinity were also measured using profilometry, energy dispersive X-ray (EDX), scanning electron microscopy (SEM), and X-ray diffraction (XRD), respectively. It is shown that over 40% material utilisation can be achieved depending on the deposition parameters of substrate temperature and speed, partial pressure of precursors and total gas flow. The activation energy derived from an Arrhenius plot of deposition rate equals 49 kJ mol-1 and is consistent with previous reports of MOCVD CdTe using a horizontal reactor. This confirms that, despite the very different reactor geometry, the alkyl radical homolysis and reaction mechanism applies in the case of the inline injector geometry in the work presented here. These results demonstrate an alternative path to high throughput processing of CdTe thin film solar cells by inline AP-MOCVD.

Barrioz, V.; Kartopu, G.; Irvine, S. J. C.; Monir, S.; Yang, X.

2012-09-01

327

Yttrium. alpha. -sialon ceramics by hot isostatic pressing and post-hot isostatic pressing  

SciTech Connect

This paper reports on dense {alpha}-sialon materials that were produced by hot isostatic pressing (HIP) and post-hot isostatic pressing (post-HIP) using composition with the formula Y{sub x}(Si{sub 12{minus}4.5x}), Al{sub 4.5x}-O{sub 1.5x},N{sub 16{minus}1.5x} with 0.1 {le} x {le} 0.9 and with the same compositions with extra additions of yttria and aluminum nitride. X-ray diffraction analyses show how the phase content changes from large amounts of {beta}-sialon (x = 0.1) to large amounts of {alpha}-sialon (x = 0.4) and increasing amounts of mellilite and sialon polytypoids (x = 0.8). Samples HIPed at 1600{degrees}C for 2 h contained unreacted {alpha}-silicon nitride, while those HIPed at 1750{degrees}C for 1 h did not. This could be due to the fact that the time is too short to achieve equilibrium or that the high pressure (200 MPa) prohibits {alpha}-sialon formation. Sintering at atmospheric pressure leads to open porosity for all compositions except those with excess yttria. Therefore, only samples with excess yttria were post-HIPed. Microstructural analyses showed that the post-HIPed samples had the highest {alpha}-sialon content.

Bartek, A.; Johansson, T. (Dept. of Engineering Materials, Lulea Univ. of Technology, S-951 Lulea (SE)); Ekstrom, T. (AB Sandvik Hard Materials, S-126 80 Stockholm (SE)); Herbertsson, H. (School of Materials Science and Engineering, University of New South Wales, Kensington, NSW 2033 (AU))

1992-02-01

328

Piping benchmark problems for the Westinghouse AP600 Standardized Plant  

SciTech Connect

To satisfy the need for verification of the computer programs and modeling techniques that will be used to perform the final piping analyses for the Westinghouse AP600 Standardized Plant, three benchmark problems were developed. The problems are representative piping systems subjected to representative dynamic loads with solutions developed using the methods being proposed for analysis for the AP600 standard design. It will be required that the combined license licensees demonstrate that their solutions to these problems are in agreement with the benchmark problem set.

Bezler, P.; DeGrassi, G.; Braverman, J.; Wang, Y.K.

1997-01-01

329

Renin Release  

NSDL National Science Digital Library

The aspartyl-protease renin is the key regulator of the renin-angiotensin-aldosterone system, which is critically involved in salt, volume, and blood pressure homeostasis of the body. Renin is mainly produced and released into circulation by the so-called juxtaglomerular epithelioid cells, located in the walls of renal afferent arterioles at the entrance of the glomerular capillary network. It has been known for a long time that renin synthesis and secretion are stimulated by the sympathetic nerves and the prostaglandins and are inhibited in negative feedback loops by angiotensin II, high blood pressure, salt, and volume overload. In contrast, the events controlling the function of renin-secreting cells at the organ and cellular level are markedly less clear and remain mysterious in certain aspects. The unravelling of these mysteries has led to new and interesting insights into the process of renin release.

2007-10-01

330

Determination of the Reflecting Properties of Pressed Mgo Powder.  

National Technical Information Service (NTIS)

Blocks of pressed MgO powder have recently become available for use as diffuse reflectance standards. The calibration of one such sample in the visible portion of the spectrum is described. Specifically, the total hemispherical reflectivity was determined...

D. Mary

1965-01-01

331

Industry Sector Analysis Mexico: Machine-Tools: Presses.  

National Technical Information Service (NTIS)

The market survey covers the machine tool presses market in Mexico. The analysis contains statistical and narrative information on projected market demand, end-users; receptivity of Mexican consumers to U.S. products; the competitive situation, and market...

A. Harris

1991-01-01

332

Hot isostatic pressing of glass-zeolite composites.  

National Technical Information Service (NTIS)

Glass-zeolite waste forms are being developed for immobilizing the chloride waste salt generated from the electrometallurgical treatment of spent fuel. Glass-zeolite composites with high densities were made using hot isostatic pressing (HIP) techniques. P...

M. C. Hash C. Pereira M. A. Lewis

1996-01-01

333

Poland's Press and Broadcasting Under the Gierek Regime  

ERIC Educational Resources Information Center

Reports that the Polish press and broadcasting have been carrying more news and less propaganda since the 1970 Baltic upheavel and that the Polish media are generally allowed more freedom than media in other Communist nations. (RB)

Shanor, Donald R.

1974-01-01

334

Cars & Censorship: How Advertising Pressure Can Corrupt a Free Press.  

ERIC Educational Resources Information Center

Discusses "private censorship" as it relates to car dealers and television advertising. Defines "private censorship" as that which occurs when a broadcaster suppresses or alters a news story that affects commercial clients (advertisers). Makes recommendations for a freer press. (JOW)

Collins, Ronald K. L.

1992-01-01

335

Consolidation of Si3N4 by hot isostatic pressing  

NASA Technical Reports Server (NTRS)

Silicon nitride (Si3N4) is being considered for gas turbine engine applications because present-day metallic alloys are rapidly approaching the limits of their temperature capabilities. The present investigation was undertaken to determine the feasibility of producing a sound, dense Si3N4 body without additives, using conventional gas hot-isostatic-pressing techniques and an uncommon hydraulic hot-isostatic-pressing technique. These two hot-isostatic-pressing (HIP) techniques produce much higher pressure (275-413 MN/sq m) than conventional hot-pressing techniques and have the potential of producing large bodies of desirable shapes. Evaluation was based on density measurement, microscopic examination, both optical and electron, and X-ray diffraction analysis.

Yeh, H. C.; Sikora, P. F.

1979-01-01

336

Frank Press, Long-Shot Candidate, May Become Science Adviser  

ERIC Educational Resources Information Center

Describes recent events suggesting that Frank Press, a 52-year-old geophysicist who currently heads the department of earth and planetary sciences at the Massachusetts Institute of Technology, may be named Science Advisor to the President. (MLH)

Boffey, Philip M.

1977-01-01

337

African Press Network for the 21st Century  

NSDL National Science Digital Library

The diversity of the African press presents certain challenges and opportunities, and the African Press Network for the 21st Century (RAP 21) website brings together a number of high-quality resources designed to "facilitate the exchange of innovative ideas and the latest information about the business of newspapers, issues related to press freedom and career development opportunities". RAP 21 was launched by the World Association of Newspapers and the Union of Publishers in Central Africa in September 2000, and is currently supported by the Swedish press group Stampen. On the homepage, visitors can delve into the "Newspaper Management Archive", which contains recent news articles about issues facing African newspapers and media, including ethics, new technologies, media laws, online publishing, and reporting on HIV/AIDS. Additionally, users can also search the complete archives and sign a protest letter to assist the cause of journalism should they so desire.

338

Development of Large Size Fully Automated Forging Press Line.  

National Technical Information Service (NTIS)

Large parts with such complicated configurations as steering knuckle, call for a higher degree of rigidity than any commercially available standard type automated forging presses can meet. Therefore, it is vital to increase the rigidity of the stamping ma...

I. Mizutani T. Karata K. Takebayashi H. Nakamura

1988-01-01

339

Renovation of the hot press in the Plutonium Experimental Facility  

SciTech Connect

The Plutonium Experimental Facility (PEF) will be used to develop a new fuel pellet fabrication process and to evaluate equipment upgrades. The facility was used from 1978 until 1982 to optimize the parameters for fuel pellet production using a process which was developed at Los Alamos National Laboratory. The PEF was shutdown and essentially abandoned until mid-1987 when the facility renovations were initiated by the Actinide Technology Section (ATS) of SRL. A major portion of the renovation work was related to the restart of the hot press system. This report describes the renovations and modifications which were required to restart the PEF hot press. The primary purpose of documenting this work is to help provide a basis for Separations to determine the best method of renovating the hot press in the Plutonium Fuel Fabrication (PuFF) facility. This report also includes several SRL recommendations concerning the renovation and modification of the PuFF hot press. 4 refs.

Congdon, J.W.; Nelson, G.H.

1990-03-05

340

5. FOURTH FLOOR, HOTEL SOAP LINES TO NORTHWEST: PRESS (LEFT ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. FOURTH FLOOR, HOTEL SOAP LINES TO NORTHWEST: PRESS (LEFT CENTER), MANUAL CUTTERS (CENTER, RIGHT CENTER) - Colgate & Company Jersey City Plant, Building No. B-15, 90-96 Greene Street, Jersey City, Hudson County, NJ

341

8. Second floor front apartment showing ornately painted pressed metal ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. Second floor front apartment showing ornately painted pressed metal ceiling, as well as modern partitions and wall treatments. View looking north. - Franklin Grocery Company Building, 1 South Main Street, Franklin, Merrimack County, NH

342

VIEW OF INTERIOR SPACE WITH HUFFORD BULLDOZIER FORMING PRESS IN ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW OF INTERIOR SPACE WITH HUFFORD BULLDOZIER FORMING PRESS IN FOREGROUND, FACING NORTHWEST. - Douglas Aircraft Company Long Beach Plant, Aircraft Parts Shipping & Receiving Building, 3855 Lakewood Boulevard, Long Beach, Los Angeles County, CA

343

VIEW OF INTERIOR SPACE WITH SQUARE SHAPE STRETCH PRESS CONTAINMENT ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW OF INTERIOR SPACE WITH SQUARE SHAPE STRETCH PRESS CONTAINMENT PITS CENTER, FACING NORTH. - Douglas Aircraft Company Long Beach Plant, Aircraft Parts Shipping & Receiving Building, 3855 Lakewood Boulevard, Long Beach, Los Angeles County, CA

344

VIEW OF INTERIOR SPACE WITH RECTANGULAR SHAPE STRETCH PRESS CONTAINMENT ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

VIEW OF INTERIOR SPACE WITH RECTANGULAR SHAPE STRETCH PRESS CONTAINMENT PIT IN BACKGROUND, FACING NORTH. - Douglas Aircraft Company Long Beach Plant, Aircraft Parts Shipping & Receiving Building, 3855 Lakewood Boulevard, Long Beach, Los Angeles County, CA

345

Hot pressed GdIG for magnetooptic memory application  

Microsoft Academic Search

This paper describes the preparation of polycrystalline GdIG by hot pressing and reports the most relevant properties of the material. Hot pressed samples were prepared using various conditions of time (1 to 20 hours), temperature (900 to 1300°C), and pressure (300 to 1000 kg\\/cm2). Dense specimens with grain diameter ranging from 1 to 10?m were prepared. Thin wafers made by

P. Coeure; F. Forrat; J.-C. Gay

1969-01-01

346

Graphite and boron carbide composites made by hot-pressing  

Microsoft Academic Search

Composites consisting of graphite and boron carbide were made by hot-pressing mixed powders of coke carbon and boron carbide. The change of relative density, mechanical strength and electrical resistivity of the composites and the X-ray parameters of coke carbon were investigated with increase of boron carbide content and hot-pressing temperature. From these experiments, it was found that boron carbide powder

Kenji Miyazaki; Tsuyoshi Hagio; Kazuo Kobayashi

1981-01-01

347

Graphite and boron carbide composites made by hot-pressing  

Microsoft Academic Search

Composites consisting of graphite and boron carbide were made by hot-pressing mixed powders of coke carbon and boron carbide.\\u000a The change of relative density, mechanical strength and electrical resistivity of the composites and the X-ray parameters\\u000a of coke carbon were investigated with increase of boron carbide content and hot-pressing temperature. From these experiments,\\u000a it was found that boron carbide powder

Kenji Miyazaki; Tsuyoshi Hagio; Kazuo Kobayashi

1981-01-01

348

As Fragile as a Crystal Glass: Press Freedom in Iran  

NSDL National Science Digital Library

This item from Human Rights Watch (HRW) explores the difficulties encountered by the independent reformist press in Iran in the face of determined conservative efforts to suppress it and prosecute journalists. The 21-page report also considers recent threats to the Iranian Press Law of 1985 and makes recommendations to the Government of Iran and the international community. This report is offered by chapter in HTML format.

Hicks, Elahe S.

349

Gemini 10 prime crew during post flight press conference  

NASA Technical Reports Server (NTRS)

At podium during Gemini 10 press conference are (l-r) Dr. Robert C. Seamans, Astronauts John Young and Michael Collins and Dr. Robert R. Gilruth (39895); Wide angle view of the Manned Spacecraft Center (MSC) News Center during the Gemini 10 prime crew post flight press conference (38786); Astronaut Young draws diagram on chalk board of tethered extravehicular activity accomplished during Gemini 10 flight (39897).

1966-01-01

350

Hand pressing device for making fuel briquettes from soaked paper  

SciTech Connect

A hand pressing device includes a pressing die in the form of an open-topped rectangular box having a loose perforated bottom plate. The inner walls of the box are smooth. The box is filled with soaked waste paper, particularly old newspapers and a loose pressing plunger with a flat perforated bottom is pressed into the box down to a predetermined penetration depth, whereby water is squeezed out of the soaked paper and escapes both upwards through the perforated bottom of the plunger and downwards through the perforated bottom plate of the box to form a briquette of predetermined dimensions and predetermined density. Upon withdrawal and removal of the pressing plunger and inversion of the box to an upside down position, the briquette thus produced can readily be pressed out of the box by exerting thumb pressure on the loose bottom plate. The side and end faces of the briquette slide along the inner wall of the box with low friction and without being torn. After drying in air, the briquette forms an excellent fuel for fireplaces and stoves.

Foldbjerg, E.

1984-07-24

351

Hot-pressing of TiC-graphite composite materials  

SciTech Connect

Monolithic TiC and TiC-graphite composites were hot-pressed at temperatures ranging from 1,800 to 2,100 C and with graphite contents up to 30 wt%. Densification behavior was compared for both monolith and composites based on results of microstructural observation and mechanical tests. Monolithic TiC was well densified at the hot-pressing temperature of 1,800 C; significant grain growth and an accompanying decrease in the flexural strength occurred with an increase in hot-pressing temperature. Conversely, the 10 wt% graphite-containing TiC composite required higher temperatures (1,900 to [approximately]2,000 C) to reach a similar degree of densification approaching that of monolithic TiC. As with densification, flexural strength of the composite increased with an increase in hot-pressing temperature. Graphite dispersions in the composites inhibited grain growth of TiC. Contrary to the equiaxed nature of the monolithic TiC grains, in the composite system, the graphite grains were flattened to thin platelets that aligned perpendicular to the hot-pressing axis. Apparent anisotropy in the microstructure was observed in the composites. At a fixed hot-pressing temperature, the relative density of the composites decreased with increasing graphite content.

Ono, T.; Endo, H.; Ueki, M. (Nippon Steep Corp., Kawasaki (Japan). Advanced Materials and Technology Research Lab.)

1993-10-01

352

APS Forum on Education Newsletter - Summer 2010 Edition  

NSDL National Science Digital Library

In the Teacher Preparation Section of this edition, Gay Stewart talks about the Arkansas Noyce Scholarship Program and Gabe Popkin discusses the PhysTEC Noyce. Other articles include an introduction to the APS Minority Bridge Program and an outline of some student opportunities available through the Center for Excellence in Education.

2010-07-06

353

Tank 241-AP-106 tank characterization plan: Revision 1  

SciTech Connect

Tank 241-AP-106 (AP-106) is a candidate feed tank which is expected to be processed at the 242-A Evaporator. Three issues related to the overall concern of the evaporator must be evaluated: compatibility of the candidate waste with respect to feed tank, slurry tank, and evaporator requirements; safety parameters of the candidate waste tank to avoid a facility condition which is outside the safety boundaries; and compliance of the waste as dictated by regulations from various government and environmental agencies. The characterization efforts of this Tank Characterization Plan are focused on the resolution of the issues above. To evaluate the potential for waste incompatibility with the feed tank, slurry tank, and evaporator, as well as relevant safety issues, analyses will be performed on the grab samples obtained from tank AP-106. These analyses are discussed in Section 4.0. Once the characterization of tank AP-106 has been performed, the waste compatibility and safety assessment shall be conducted. This effort is discussed elsewhere.

Valenzuela, B.D.

1994-11-17

354

84th President of APS Joey P. Granger  

NSDL National Science Digital Library

This article is on pages 41 and 45-49 of the PDF file. An article in The Physiologist April 2011 introducing Joey P. Granger and outlining what he views as the areas of strength in the APS and areas where improvment is needed.

PhD Joey P. Granger (University of Mississippi Medical Center Department of Physiology)

2011-04-01

355

Fabrication of the APS Storage Ring radio frequency accelerating cavities  

SciTech Connect

Specification, heat treatment, strength, and fatigue life of the Advanced Photon Source (APS) Storage Ring 352-MHz radio frequency (RF) accelerating cavity copper is discussed. Heat transfer studies, including finite element analysis, and configuration of water cooling is described. Requirements for and techniques of machining are considered. Braze and electron beam joint designs are compared. Vacuum considerations during fabrication are discussed.

Primdahl, K.; Bridges, J.; DePaola, F.; Kustom, R. [Argonne National Lab., IL (US); Snee, D. [Fermi National Accelerator Lab., Batavia, IL (US)

1993-07-01

356

AP Biology Workshop: The Importance of Laboratory Work  

NSDL National Science Digital Library

This is a collection of essays that highlights the benefits of conducting lab experiments as part of the AP Biology curriculum. It encourages teachers to continue using learning tools like technology in lab experiments to enhance the classroom experience for students.

The College Board The College Board (The College Board;); Carolyn Schofield (The College Board;)

2012-10-24

357

Positron Accumulator Ring for the APS (Advanced Photon Source).  

National Technical Information Service (NTIS)

The Positron Accumulator Ring (PAR) is designed to accumulate and damp positrons from the 450-MeV linac during the 0.5-s cycle time of the injector synchrotron for the APS 7-GeV storage ring. During 0.4 s of each synchrotron cycle, up to 24 linac pulses a...

E. A. Crosbie

1989-01-01

358

Tank 241AP104 Grab Sampling and Analysis Plan  

SciTech Connect

This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for samples obtained from tank 241-AP-104. The purpose of this sampling event is to obtain information about the characteristics of the contents of 241-AP-104 required to provide sample material to the Waste Treatment Contractor. Grab samples will be obtained from riser 001 to provide sufficient material for the chemical analyses and tests required to satisfy these data quality objectives and ICD-23. The 222-S Laboratory will receive samples; composite the samples; perform chemical analyses on composite samples; and provide samples to the Waste Treatment Contractor and the Process Chemistry Laboratory. The Process Chemistry Laboratory at the 222-S Laboratory Complex will perform process tests to evaluate the behavior of the 241-AP-104 waste undergoing the retrieval and treatment scenarios defined in the applicable DQOs. The Waste Treatment Contractor will perform process verification and waste form qualification tests. Requirements for analyses of samples originating in the L & H DQO process tests will be documented in the corresponding test plan (Person 2000) and are not within the scope of this SAP. This report provides the general methodology and procedures to be used in the preparation, retrieval, transport, analysis, and reporting of results from grab samples retrieved from tank 241-AP-104.

TEMPLETON, A.M.

2000-11-09

359

Copper corrosion & clogging in APS deionized water cooling system  

Microsoft Academic Search

An extensive amount of work has been performed on copper corrosion in last century due to its abundant use in domestic and industrial water systems. However, work on copper corrosion in deionized water is very limited. The water cooling system of Advanced Photon Source (APS) at Argonne National Laboratory uses deionized water containing very low dissolved oxygen (less than 10

Bijaya Adak

2009-01-01

360

The Delta 125 Steam Generator Design for the AP1000  

SciTech Connect

The Advanced Plant 1000 uses two Delta 125 steam generators, with each steam generator rated at 1707.5 MWt. The AP1000 Delta 125 steam generator design has many features that represent 'best practices' with respect to steam generator design and reliability and long-term performance. These features are summarized in this paper. (authors)

Condrac, Robert F.; Waszink, Remco P.; Pankiewicz-Nohr, Christopher G. [Westinghouse Electric Company, LLC, Post Office Box 158, Madison, PA 15663-0158 (United States)

2004-07-01

361

Improved temperature regulation of APS linac RF components.  

National Technical Information Service (NTIS)

The temperature of the APS S-Band linac's high-power rf components is regulated by water from individual closed-loop deionized (DI) water systems. The rf components are all made of oxygen-free high-conductivity copper and respond quickly to temperature ch...

R. Dortwegt

1998-01-01

362

Tank 241AP102 Vapor Sampling and Analysis Plan  

Microsoft Academic Search

This tank sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for vapor samples from the head space of tank 241-AP-102. Sampling will be performed in accordance with ''Data Quality Objectives for Regulatory Requirements for Hazardous and Radioactive Air Emissions Sampling and Analysis'' (Air DQO) (Mulkey 1999). The sample results will

2001-01-01

363

AP: A Critical Examination of the Advanced Placement Program  

ERIC Educational Resources Information Center

With an annual yearly growth rate of 9.3 percent over the last two decades, Advanced Placement courses have become a juggernaut in American high school education. AP courses are routinely perceived as an indicator of educational rigor, and many schools push to enroll low-income or minority students in these courses in the hope of preparing them…

Sadler, Philip M., Ed.; Sonnert, Gerhard, Ed.; Tai, Robert H., Ed.; Klopfenstein, Kristin, Ed.

2010-01-01

364

The accretion of interplanetary dust by Ap and Am stars  

NASA Technical Reports Server (NTRS)

Accretion of interplanetary dust and comets by A-type stars is investigated to see whether this process can explain the overabundances of heavy elements in Ap and Am stars. The dust particles spiral in by the Poynting-Robertson effect and evaporate above the star. This process is evaluated by considering the evolution of silicate and graphite particles in the radiation field of Alpha Leo (B7 V). It is found that graphite particles evaporate above 20 stellar radii and silicate dust grains above 50 stellar radii. The evaporated atoms will be quickly ionized. In the case of Am stars the ions will wander off and not reach the photosphere, but in the case of Ap stars they can be trapped by the magnetic field of the star and reach the surface. The magnetosphere of a typical Ap star is modeled, and the fate of the ions is studied. The efficiency of accretion from the magnetosphere is sensitive to the presence of any plasma in the magnetosphere. The comet impact process is found capable of producing the abundance anomalies in Ap as well as Am stars, assuming that the comet impact rate is 0.03/yr, nearly the same as in the solar system.

Kumar, C. Krishna; Davila, Joseph M.; Rajan, R. Sundar

1989-01-01

365

Simulation of the APS storage-ring rf system  

SciTech Connect

A simulation model for the APS storage ring rf system has been developed that includes the effects of cavity impedances, longitudinal beam dynamics, and generator klystrons. The model predicts multiple-bunch longitudinal beam behavior and is used for feedback system design and stability analysis.

Schwartz, C.; Nassiri, A.; Kang, Y.; Kustom, R.L.

1997-08-01

366

A process definition repository based on step AP 213  

SciTech Connect

Over the years, in the context of numerically controlled machined part manufacturing, the loss, misinterpretation, and redundancy of re-inputting manufacturing instructions and data during the evolution of a product design into the finished product has been a resource depleting and costly endeavor. It is the intent of this project to utilize the emerging standards from the International Standards Organization, ISO 10303 Standard for the Exchange of Product Model Data, commonly referred to as STEP, to store and retrieve process planning information for a set of production work instructions. The project focuses on the utilization of the 1995 version of the Draft International Standard ISO/DIS 10303-213:1995 (E) Application protocol: Numerical control process plans for machined parts (AP213). This project illustrates the methodologies used to build an object-oriented Process Definition Repository (PDR), describes both the benefits and shortcomings experienced in implementing AP213, and recommends enhancements to AP213 for process planning information. The deliverable will be a Part 21 data file, based on the application-interpreted model for AP213 and integrated with product design data.

Butler, J.W.

1997-09-01

367

A preliminary analysis of the APS crotch design  

Microsoft Academic Search

A preliminary design analysis of the absorber plate of the proposed crotch for the APS bending magnet radiation is presented. Various design aspects including thermal and structural considerations, material selection, geometry, and cooling method are discussed and a number of recommendations are made.

Khounsary

1990-01-01

368

Nuclear Reactor Safety--The APS Submits its Report  

ERIC Educational Resources Information Center

Presents the summary section of the American Physical Society (APS) report on the safety features of the light-water reactor, reviews the design, construction, and operation of a reactor and outlines the primary engineered safety features. Summarizes the major recommendations of the study group. (GS)

Physics Today, 1975

1975-01-01

369

ACTIVATION OF AP-1 IN UROTSA CELLS BY METHYLATED ARSENICALS  

EPA Science Inventory

ACTIVATION OF AP-1 IN UROTSA CELLS BY METHYLATED TRIVALENT ARSENICALS. Z Drobna1, I Jaspers2, D J Thomas3 and M Styblo1. 1Department of Pediatrics; 2Center for Environmental Medicine and Lung Biology, University of North Carolina at Chapel Hill, NC, USA; 3US EPA, RTP, NC, USA....

370

APS Represented at the National Association of Biology Teachers  

NSDL National Science Digital Library

This is an article from The Physiologist. "Margaret Shain and Tonya Smith, both current Mentor/Instructors for the 2007 Frontiers in Physiology Fellowship for science teachers, assisted Education Office members, Scarletta Whitsett and Mel Limson, and represented the APS at the National Association of Biology Teachers 2007 Professional Development Conference at the end of November in Atlanta, GA."

2008-02-01

371

Alignment and commissionig of the APS beamline front ends.  

National Technical Information Service (NTIS)

Fifteen out of forty phase-one beamline front ends have been installed in the storage-ring tunnel at the 7-GeV Advanced Photon Source (APS). For the front-end installation, a four-step alignment process was designed and consists of (1) prealigning the fro...

D. Shu J. Barraza M. Ramanathan J. Chang T. M. Kuzay

1995-01-01

372

HIT collaborative base project at APS of Argonne  

NASA Astrophysics Data System (ADS)

Harbin Institute of Technology (HIT) launched collaborative base project at Argonne National Laboratory in 2010, and progress will be presented in this paper. The staff and students from HIT involved in advanced technological developments, which included tomography. high energy PDF, diffraction and scattering, and inelastic scattering techniques in APS to study structures changes under high pressure conditions.

Liu, H.; Wang, L.

2012-12-01

373

A Key Telegram and a Key Press Release on the Recognition of the State of Israel  

ERIC Educational Resources Information Center

Reviews the course of events leading to the founding of Israel in 1947. Presents primary source materials, activities, and discussion questions to help students analyze reasons for the Arab-Israeli conflict. (Author/DB)

Byers, CeCe; Alexander, Mary

1978-01-01

374

Impact Initiation of Rods of Pressed Polytetrafluoroethylene (PTFE) and Aluminum Powders  

NASA Astrophysics Data System (ADS)

A gas gun has been used to investigate the impact initiation of rods consisting of a mixture of 72 wt% PTFE (28 ?m particle size) and 28 wt% aluminum (95 micron particle size) powders. The rods were 7.6 mm in diameter by 51 mm long, and were fabricated from material that had been pressed and sintered to a full density of 2.27 gm/cm^ 3. They were sabot-launched into steel anvils at impact velocities ranging from 468 to 970 m/sec. This corresponds to calculated initial impact stresses of 25 to 64 kbar, respectively. A framing camera was used to observe the time sequence of events. These include change in rod shape, fracture, and the initiation and evolution of the reaction phenomena. The time of observation of first light after impact was taken as the initiation time. Initiation occurred at discrete locations in the impacted material. At the lowest impact stress of 25 kbar no light was observed; this value was taken as the initiation threshold stress for this material. Above the initiation threshold, the initiation time dropped abruptly from 74 ?s just above threshold to 14 ?s at the highest impact velocity of 970 m/s. These results are compared with rod impact experiments for a similar material [1] in which the only major difference is a smaller aluminum particle size (9 micron). [1] W. Mock, Jr. and W. H. Holt, in Proc. APS Shock Compression of Condensed Matter--2005, p.1097.

Mock, Willis, Jr.; Drotar, Jason T.

2007-06-01

375

Copper corrosion & clogging in APS deionized water cooling system  

NASA Astrophysics Data System (ADS)

An extensive amount of work has been performed on copper corrosion in last century due to its abundant use in domestic and industrial water systems. However, work on copper corrosion in deionized water is very limited. The water cooling system of Advanced Photon Source (APS) at Argonne National Laboratory uses deionized water containing very low dissolved oxygen (less than 10 ppb). Therefore, It is expected that copper corrosion would be less in this system. On the contrary, APS suffers significant clogging in its water cooling circuit resulting from the deposition of corrosion product and carries out frequent expensive maintenance to retain the required flow rate. The location of pH and corrosion potential of APS water cooling system is very close to the boundary condition of the two oxides (CuO and Cu 2O) of the Pourbaix diagram of copper. While a single phase presence of either of these two oxides is stable as a protective layer, a mixture of the two oxides is unstable. An unstable protective layer results in spalling of the oxide layer. A fluctuation in water chemistry (which is common in an industrial facility) triggers a phase transformation between these two oxides due to its near boundary values. It was observed that the location of pH and corrosion potential was away from the boundaries in high dissolved oxygen condition (more than 2000 ppm). Hence, the possibility of phase transformation becomes lesser in high dissolved oxygen condition than in low dissolved oxygen condition. A test station, that was a replica of the APS water cooling system, was used to perform experiments in both high and low oxygen condition. It was demonstrated that high oxygen condition results in less clogging than in low oxygen condition. Microstructural characterization was performed on the coupons from test station and on some components from APS to evaluate oxide surface and determine phases. Mechanism of the phase transformation was suggested.

Adak, Bijaya

376

Aviation Safety Program: Weather Accident Prevention (WxAP) Development of WxAP System Architecture And Concepts of Operation  

NASA Technical Reports Server (NTRS)

This paper presents viewgraphs on the development of the Weather Accident Prevention (WxAP) System architecture and Concept of Operation (CONOPS) activities. The topics include: 1) Background Information on System Architecture/CONOPS Activity; 2) Activity Work in Progress; and 3) Anticipated By-Products.

Grantier, David

2003-01-01

377

Modulation of dopamine release in the striatum by physiologically relevant levels of nicotine.  

PubMed

Striatal dopamine (DA) release can be independently triggered not only by action potentials (APs) in dopaminergic axons but also APs in cholinergic interneurons (ChIs). Nicotine causes addiction by modulating DA release, but with paradoxical findings. Here, we investigate how physiologically relevant levels of nicotine modulate striatal DA release. The optogenetic stimulation of ChIs elicits DA release, which is potently inhibited by nicotine with an IC50 of 28?nM in the dorsal striatum slice. This ChI-driven DA release is predominantly mediated by ?6?2* nAChRs. Local electrical stimulus (Estim) activates both dopaminergic axons and ChIs. Nicotine does not affect the APDA-dependent DA release (APDA, AP of dopaminergic axon). During burst Estim, nicotine permits the facilitation of DA release by prevention of DA depletion. Our work indicates that cholinergic stimulation-induced DA release is profoundly modulated by physiologically relevant levels of nicotine and resolves the paradoxical observation of nicotine's effects on striatal DA release. PMID:24968237

Wang, Li; Shang, Shujiang; Kang, Xinjiang; Teng, Sasa; Zhu, Feipeng; Liu, Bin; Wu, Qihui; Li, Mingli; Liu, Wei; Xu, Huadong; Zhou, Li; Jiao, Ruiying; Dou, Haiqiang; Zuo, Panli; Zhang, Xiaoyu; Zheng, Lianghong; Wang, Shirong; Wang, Changhe; Zhou, Zhuan

2014-01-01

378

Modulation of presynaptic glucocorticoid receptors on glutamate release from rat hippocampal nerve terminals.  

PubMed

In this study, we have examined the role of corticosterone (CORT) in the regulation of neuronal glutamate release using nerve terminals (synaptosomes) isolated from the rat hippocampus. Adult male Sprague-Dawley rats received either a chronic systemic administration of CORT (daily 25 mg/kg in sesame oil, subcutaneously) or long-term bilateral adrenalectomy (ADX) (3-4 weeks), and then the release of 4-aminopyridine (4AP)-evoked endogenous glutamate and the levels of glucocorticoid receptor (GR) expression from hippocampal nerve terminals were studied. Chronic administration of CORT resulted in a significant increase of 4AP-evoked glutamate release from hippocampal nerve terminals, whereas ADX reduced 4AP-evoked glutamate release. In addition, chronic administration of CORT and ADX induced a significant reduction and increase in GR expression in hippocampal synaptosomes, respectively, as detected by Western blots. Furthermore, acute treatment of CORT or dexamethasone facilitated 4AP-evoked glutamate release from synaptosomes freshly isolated from naïve rat hippocampus and this effect can be significantly prevented by pretreatment of GR antagonist mifepristone, but not by mineralocorticoid receptor (MR) antagonist RU28318. Together, our results strongly support the presence of GRs on presynaptic nerve terminals in the rat hippocampus acting to facilitate the release of neuronal glutamate. PMID:19484722

Wang, Chia-Chuan; Wang, Su-Jane

2009-09-01

379

NF-?B and AP-1 Connection: Mechanism of NF-?B-Dependent Regulation of AP-1 Activity  

PubMed Central

Nuclear factor ?B (NF-?B) and activator protein 1 (AP-1) transcription factors regulate many important biological and pathological processes. Activation of NF-?B is regulated by the inducible phosphorylation of NF-?B inhibitor I?B by I?B kinase. In contrast, Fos, a key component of AP-1, is primarily transcriptionally regulated by serum responsive factors (SRFs) and ternary complex factors (TCFs). Despite these different regulatory mechanisms, there is an intriguing possibility that NF-?B and AP-1 may modulate each other, thus expanding the scope of these two rapidly inducible transcription factors. To determine whether NF-?B activity is involved in the regulation of fos expression in response to various stimuli, we analyzed activity of AP-1 and expression of fos, fosB, fra-1, fra-2, jun, junB, and junD, as well as AP-1 downstream target gene VEGF, using MDAPanc-28 and MDAPanc-28/I?B?M pancreatic tumor cells and wild-type, IKK1?/?, and IKK2?/? murine embryonic fibroblast cells. Our results show that elk-1, a member of TCFs, is one of the NF-?B downstream target genes. Inhibition of NF-?B activity greatly decreased expression of elk-1. Consequently, the reduced level of activated Elk-1 protein by extracellular signal-regulated kinase impeded constitutive, serum-, and superoxide-inducible c-fos expression. Thus, our study revealed a distinct and essential role of NF-?B in participating in the regulation of elk-1, c-fos, and VEGF expression.

Fujioka, Shuichi; Niu, Jiangong; Schmidt, Christian; Sclabas, Guido M.; Peng, Bailu; Uwagawa, Tadashi; Li, Zhongkui; Evans, Douglas B.; Abbruzzese, James L.; Chiao, Paul J.

2004-01-01

380

An Update of Freedom of the Press and Information in Latin America and the Caribbean.  

ERIC Educational Resources Information Center

This paper is based on a review of the literature that included reports from the Inter-American Press Association's general assembly in Los Angeles in October 1984, the mid-year meeting of the Inter-American Press Association in Panama City in March 1985, and the 1983 world press freedom review of the International Press Institute. Other material…

Garrison, Bruce; Munoz, Julio E.

381

Quality parameters for cold pressed edible argan oils.  

PubMed

Argan oil belongs to the high-price vegetable oils on the market. Therefore, consumers have the right to purchase a high-quality product. The quality of edible vegetable oils is defined in food standards in which sensory quality is the most important feature. Additional parameters are defined to assess the identity of oils or to evaluate their oxidative state. The sensory quality of cold pressed argan oil is altered if the production has not been performed with reasonable care regarding raw material and extraction. Only oil from roasted seeds extracted by a screw-press had a sufficient sensory quality over a period of 20 weeks without unacceptable sensory attributes. Under accelerated storage conditions oil from roasted seeds extracted by a screw-press remained below the limits given by the Codex Alimentarius or the German guideline for Edible Fats and Oils for peroxide and totox value. Oil from unroasted seeds or oil from goat-digested roasted seeds and extracted by a screw-press, as well as oil from roasted seeds traditionally extracted, exceeded these limits. Initial oxidative stability of oil from unroasted seeds was significantly lower than that of the other oils. After 35 days under accelerated storage, oil from roasted seeds obtained using a screw-press showed the highest oxidative stability. Moreover, tocopherol and phytosterol compositions are useful features of argan oil. PMID:23472455

Matthäus, Bertrand

2013-01-01

382

Should roAp Stars get Wet and Will they Make a Splash?  

NASA Astrophysics Data System (ADS)

The one attempt (in 1989) to monitor a rapidly oscillating Ap (roAp) star with the WET network was a failure, but for reasons which are now clearly recognized and correctable. In the meantime, roAp research has blossomed to the point that we are better able to extract astrophysical information about these magnetic stars from WET-quality data. The time is ripe for a WET campaign on a multi-mode roAp pulsator.

Matthews, J.

1998-03-01

383

77 FR 35308 - Proposed Amendment of Restricted Area R-6601; Fort A.P. Hill, VA  

Federal Register 2010, 2011, 2012, 2013

...Amendment of Restricted Area R-6601; Fort A.P. Hill, VA AGENCY: Federal Aviation Administration...designation of restricted area R-6601, Fort A.P. Hill, VA. The U. S. Army requested...Banks, U.S. Army Garrison, Fort A.P. Hill, VA 22427; telephone: (804)...

2012-06-13

384

Using a Classroom Response System to Improve Multiple-Choice Performance in AP[R] Physics  

ERIC Educational Resources Information Center

Participation in rigorous high school courses such as Advanced Placement (AP[R]) Physics increases the likelihood of college success, especially for students who are traditionally underserved. Tackling difficult multiple-choice exams should be part of any AP program because well-constructed multiple-choice questions, such as those on AP exams and…

Bertrand, Peggy

2009-01-01

385

78 FR 21817 - Amendment of Restricted Area R-6601; Fort A.P. Hill, VA  

Federal Register 2010, 2011, 2012, 2013

...R-6601; Fort A.P. Hill, VA AGENCY: Federal Aviation Administration...R-6601, Fort A.P. Hill, VA. The U.S. Army requested...R-6601, Fort A.P. Hill, VA, (77 FR 35308, June 13, 2012...written comments on the proposal. One comment was received....

2013-04-12

386

The Role of ? -Aminopropyltriethoxysilane (? APS) on Thermal Stability of TEOS-PDMS Ormosils  

Microsoft Academic Search

The degradation process of TEOS-PDMS Ormosils containing different amounts of ? -APS has been studied by means of DTA, TG, FTIR and 29Si-NMR measurements. It has been found that the amount of ? -APS improved the thermal properties of Ormosil materials. The increase in ? -APS content causes the increment on the decomposition temperatures and activation energies of the studied

R. Peña-Alonso; F. Rubio; J. Rubio

2005-01-01

387

Biomedical Applications of Microprobe Analysis (APS Colloquium, 2005)  

SciTech Connect

Microprobe analysis in biology is used here mainly in the context of acquisition and analysis of compositional data at cellular and subcellular spatial resolutions using microbeams on the nanometer scale. Clearly this is only one aspect of a very broad field of scientific inquiry that generally falls under the rubric of compositional imaging that can involve many different sources of radiation including electrons, ions, and photons. Indeed there are often subtle distinctions in biological microscopy between structural microanatomy and chemical microanatomy - they obviously can be significantly different, for example during the early stages of cell injury when changes in the elemental distribution within a cell can become readily apparent before any observable changes in morphology via conventional microscopy. [See the entire abstract at http://www.aps.anl.gov/News/Meetings/APS_Colloquium/2005/IngramAbstr_long1.pdf

Ingram, Peter (Duke University Medical Center) [Duke University Medical Center

2005-01-24

388

RF characteristics of the APS storage ring isolation valve  

SciTech Connect

The RF impedance of the sector isolation valve of the APS storage ring system was measured by the wire method with a synthetic pulse technique. The coupling impedance as well as the energy loss of the isolation valve with and without an RF liner or screen, and the flange gap of the various sizes was calculated from the measurements. There appear to be resonances at certain frequencies in the absence of an RF liner that might cause an unacceptably large coupling impedance. Data with various sizes of the flange gap show that a good RF contact around any flange is necessary. The results also are compared with computer simulation from MAFIA. The measured impedance due to the RF liner alone is within 0.2% of the total APS impedance budget.

Song, J.J.

1993-03-31

389

Lithium in roAp stars with strong magnetic fields  

NASA Astrophysics Data System (ADS)

We discuss lithium abundance and 6Li/7Li isotopic ratio in atmospheres of some magnetic roAp stars. Overabundances of the lithium were found in atmospheres of some roAp stars based on the analysis of both lithium lines at 6104 Å and 6708 Å as well as the high values of the 6Li/7Li isotopic ratio (0.2 - 0.5). These facts can be explained by lithium production in spallation reactions on stellar surface and by preserving 7Li and 6Li isotopes to be destroyed in the inner layers of stellar atmospheres by strong magnetic fields near magnetic poles. Our synthetic spectrum calculations take into account magnetic line broadening effects.

Polosukhina, N.; Shavrina, A.; Drake, N. A.; Smirnova, M.

390

Tank 241-AP-107 tank characterization plan. Revision 1  

SciTech Connect

Defense Nuclear Facilities Safety Board has directed the DOE to concentrate ear-term sampling and analysis activities on identification and resolution of issues (Conway 1993). The Data Quality Objective (DQO) process was chosen as a tool to be used in the resolution of safety issues. As a result, a revision in the Federal Facilities Agreement and Consent Order (Tri-Party Agreement) milestone M-44-00 has been made, which states that ``A Tank Characterization Plan (TCP) will be developed for each double-shell tank (DST) and single-shell tank (SST) using the DQO process; Development of TCPs by the DQO process is intended to allow users (e.g., Hanford Facility user groups, regulators) to ensure their needs will be met and that resources are devoted to gaining only necessary information.`` This document satisfies that requirement for the tank 241-AP-107 (AP-107).

Schreiber, R.D. [Westinghouse Hanford Co., Richland, WA (United States)

1995-01-20

391

Variations of Ap stars in the Geneva system (Manfroid+ 1998)  

NASA Astrophysics Data System (ADS)

The photometric behaviour of 21 Ap stars has been analyzed from observations obtained in the Geneva system. Variability has been detected for 9 Ap stars, as well as for a star which initially was a comparison star. Preliminary values for the periods are presented as well as an analytical description of the light curves. The material has been collected during a 23-night observing run at La Silla with the 70cm telescope of the Geneva Observatory equipped with the standard Geneva photometer. The parameters of a second-order cosine fit to the lightcurves are stored in the accompanying table. Time origin is JD 2450000.0. The 17 phase diagrams for each of the 9 stars are presented in 9 postscript files. The observational data are superimposed on the Fourier fit. Data are differential, except for HD 191439 and HD 192674 which had no suitable comparisons. (1 data file).

Manfroid, J.; Burnet, M.; Renson, P.

1997-08-01

392

Devic's syndrome and primary APS: a new immunological overlap.  

PubMed

Neuromyelitis optica (NMO or Devic's syndrome) is a rare autoimmune disease, previously considered a multiple sclerosis variant. The most important laboratory and clinical features are optic myelitis and transverse myelitis, associated with neuromyelitis optica-IgG antibody (NMO-IgG) positivity. Subsequent to this immunological test being available, different groups have described the not-so-rare comorbidity of neuromyelitis optica with other systemic autoimmune diseases, systemic lupus erythematosus with secondary anti-phospholipid syndrome (APS) in particular. We describe a patient meeting both the classification criteria for primary APS and the new diagnostic criteria for neuromyelitis optica. It's important to diagnose NMO syndrome as both optic neuritis and transverse myelitis were also considered neurological complications of antiphospholipid syndrome. NMO-IgG is a new and fundamental test to decide if immunosuppressant therapy is warranted for such patients. PMID:20504834

Squatrito, D; Colagrande, S; Emmi, L

2010-10-01

393

Real-time orbit feedback at the APS.  

SciTech Connect

A real-time orbit feedback system has been implemented at the Advanced Photon Source in order to meet the stringent orbit stability requirements. The system reduces global orbit motion below 30Hz by a factor of four to below 5{micro}m rms horizontally and 2{micro}m rms vertically. This paper focuses on dynamic orbit stability and describes the all-digital orbit feedback system that has been implemented at the APS. Implementation of the global orbit feedback system is described and its latest performance is presented. Ultimately, the system will provide local feedback at each x-ray source point using installed photon BPMs to measure x-ray beam position and angle directly. Technical challenges associated with local feedback and with dynamics of the associated corrector magnets are described. The unique diagnostic capabilities provided by the APS system are discussed with reference to their use in identifying sources of the underlying orbit motion.

Carwardine, J.

1998-06-18

394

Method for hot pressing irregularly shaped refractory articles  

DOEpatents

The present invention is directed to a method for hot pressing irregularly haped refractory articles with these articles of varying thickness being provided with high uniform density and dimensional accuracy. Two partially pressed compacts of the refractory material are placed in a die cavity between displaceable die punches having compact-contacting surfaces of the desired article configuration. A floating, rotatable block is disposed between the compacts. The displacement of the die punches towards one another causes the block to rotate about an axis normal to the direction of movement of the die punches to uniformly distribute the pressure loading upon the compacts for maintaining substantially equal volume displacement of the powder material during the hot pressing operation.

Steinkamp, William E. (Clinton, TN); Ballard, Ambrose H. (Knoxville, TN)

1982-01-01

395

Asynchronous decision making in a memorized paddle pressing task  

NASA Astrophysics Data System (ADS)

This paper presents a method for asynchronous decision making using recorded neural data in a binary decision task. This is a demonstration of a technique for developing motor cortical neural prosthetics that do not rely on external cued timing information. The system presented in this paper uses support vector machines and leaky integrate-and-fire elements to predict directional paddle presses. In addition to the traditional metrics of accuracy, asynchronous systems must also optimize the time needed to make a decision. The system presented is able to predict paddle presses with a median accuracy of 88% and all decisions are made before the time of the actual paddle press. An alternative bit rate measure of performance is defined to show that the system proposed here is able to perform the task with the same efficiency as the rats.

Dankert, James R.; Olson, Byron; Si, Jennie

2008-12-01

396

Solutions to Challenges Facing a University Digital Library and Press  

PubMed Central

During the creation of a university digital library and press intended to serve as a medical reference and education tool for health care providers and their patients, six distinct and complex digital publishing challenges were encountered. Over nine years, through a multidisciplinary approach, solutions were devised to the challenges of digital content ownership, management, mirroring, translation, interactions with users, and archiving. The result is a unique, author-owned, internationally mirrored, university digital library and press that serves as an authoritative medical reference and education tool for users around the world. The purpose of this paper is to share the valuable digital publishing lessons learned and outline the challenges facing university digital libraries and presses.

D'Alessandro, Michael P.; Galvin, Jeffrey R.; Colbert, Stephana I.; D'Alessandro, Donna M.; Choi, Teresa A.; Aker, Brian D.; Carlson, William S.; Pelzer, Gay D.

2000-01-01

397

Press, Regime and Society in Jordan Since 1989  

NSDL National Science Digital Library

Originally published in 1998 in the Occasional Paper series of the Inter-University Consortium for Arab Studies, Montreal, this paper by doctoral candidate Adam Jones offers a rare scholarly glimpse into recent press-regime relations in Jordan. Winner of the University of British Columbia Political Science Association Essay Prize (Ph.D. division), this paper seeks to place post-1989 events in Jordan in their historical, regional, and cultural context. "Based in part on interviews with key figures in the Jordanian press and government, it considers the complex interaction among press, regime, and society during the 1990s. A postscript appraises the situation in light of the regime's crackdown of September 1997."

Jones, Adam (Adam Jason), 1963-.

1998-01-01

398

Architecture of the APS real-time orbit feedback system.  

SciTech Connect

The APS Real-Time Orbit Feedback System is designed to stabilize the orbit of the stored positron beam against low-frequency sources such as mechanical vibration and power supply ripple. A distributed array of digital signal processors is used to measure the orbit and compute corrections at a 1kHz rate. The system also provides extensive beam diagnostic tools. This paper describes the architectural aspects of the system and describes how the orbit correction algorithms are implemented.

Carwardine, J. A.; Lenkszus, F. R.

1997-11-21

399

Posttranslational modification of mammalian AP endonuclease (APE1)  

PubMed Central

A key issue in studying mammalian DNA base excision repair is how its component proteins respond to a plethora of cell-signaling mediators invoked by DNA damage and stress-inducing agents such as reactive oxygen species, and how the actions of individual BER proteins are attributed to cell survival or apoptotic/necrotic death. This article reviews the past and recent progress on posttranslational modification (PTM) of mammalian apurinic/apyrimidinic (AP) endonuclease 1 (APE1).

Busso, Carlos S.; Lake, Michael W.

2010-01-01

400

SN 2002ap, the Hypernova of Class Ic  

Microsoft Academic Search

The supernova SN 2002ap was discovered in the outer regions of the nearby spiral M74 on January 29.4 UT. Early photometric and spectroscopic observations indicate the supernova belongs to the class of Ic hypernova. Late time (After JD 2452500) light curve decay slopes are similar to that of the hypernovae SN 1997ef and SN 1998bw. We present here the BVRI

S. B. Pandey; D. K. Sahu; G. C. Anupama; D. Bhattacharya; Ram Sagar

2003-01-01

401

Studies on Nonaluminized High Burning Rate AP-Composite Propellants  

Microsoft Academic Search

This paper discusses the effect of replacement of hydroxyl terminated poly butadiene (HTPB) by butacene on the burning rates of a nonaluminized ammonium perchlorate (AP)–based composite propellant. A remarkable burning rate enhancement (60–100%) was observed on replacement of HTPB by butacene to the extent of 25%. Replacement of 50–75% HTPB by butacene led to further increase in burning rate by

G. M. GORE; A. N. NAZARE; C. N. DIVEKAR; S. K. HAIT; S. N. ASTHANA

2004-01-01

402

Aps-based miniature sun sensor for earth observation nanosatellites  

Microsoft Academic Search

This paper describes the research activity at the university of Naples concerning the design and prototype development of a low-cost APS-based miniature sun sensor for micro\\/nanosatellites applications. In the paper the sensor architecture is described, as well as the development of its prototype and of the facility for laboratory testing. Part of the project is also the development of a

Marcello Buonocore; Michele Grassi; Giancarlo Rufino

2005-01-01

403

Mechanism of grain orientation during hot-pressing of bismuth titanate  

Microsoft Academic Search

Grain-oriented BiâTiâOââ ceramics have been prepared by hot-pressing. Platelike grains align during hot-pressing; the long-axis direction perpendicular to the crystal c axis is oriented perpendicular to the pressing direction. The authors describe the effects of hot-pressing conditions such as temperature, pressure, time, and type of filler on the density, orientation degree, and deformation of hot-pressed compacts. Sharp increases in the

Toshio Kimura; Takeshi Yoshimoto; Nobuyoshi Iida; Yoshiaki Fujita; Takashi Yamaguchi

1989-01-01

404

Pew Research Center for the People and the Press: News Audiences Increasingly Politicized  

NSDL National Science Digital Library

The Pew Research Center for the People and the Press serves as "an independent opinion research group that studies attitudes toward the press, politics and public policy issues." As such, the center frequently release various reports on a host of topics, such as those on public attitudes about the credibility and salience of the news media and in-depth surveys and analyses of the public and opinion leaders on international policy. One of the more recent reports is this 106-page document examining a number of trends, including where Americans go to find out about the news, online news readership, and the declining credibility in various media organizations. This report is based on a nationwide poll of 3000 adults, conducted over April and May of 2004, and contains a number of findings, including the fact that more and more Americans are watching Fox News on a regular basis. The report is divided into six primary sections and also includes the questionnaires on which the report is based.

405

Accuracy of press reports on gamma-ray astronomy  

NASA Astrophysics Data System (ADS)

Most Americans learn about modern science from press reports, while such articles have a bad reputation among scientists. We have performed a study of 148 news articles on gamma-ray astronomy to quantitatively answer the questions ``How accurate are press reports of gamma-ray astronomy?'' and ``What fraction of the basic claims in the press are correct?'' We have taken all articles on the topic from five news sources (UPI, New York Times, Sky & Telescope, Science News, and five middle-sized city newspapers) for one decade (1987-1996) We found an average rate of roughly one trivial error every two articles, while none of our 148 articles significantly mislead the reader or misrepresented the science. This quantitative result is in stark contrast to the nearly universal opinion among scientists that the press frequently butchers science stories. So a major result from our study is that reporters should be rehabilitated into the good graces of astrophysicists, since they actually are doing a good job. For our second question, we rated each story with the probability that its basic new science claim is correct. We found that the average probability over all stories is 70%. Since the reporters and the scientists are both doing good jobs, then why is 30% of the science you read in the press wrong? The reason is that the nature of news reporting is to present front-line science and the nature of front-line science is that reliable conclusions have not yet been reached. The combination of these two natures forces fast breaking science news to have frequent incorrect ideas that are subsequently identified and corrected. So a second major result from our study is to make the distinction between textbook science (with reliabilities near 100%) and front-line science which you read about in the press (with reliabilities near 70%). .

Schaefer, Bradley E.; Nemiroff, Robert J.; Hurley, Kevin

2000-09-01

406

Process design of press hardening with gradient material property influence  

NASA Astrophysics Data System (ADS)

Press hardening is currently used in the production of automotive structures that require very high strength and controlled deformation during crash tests. Press hardening can achieve significant reductions of sheet thickness at constant strength and is therefore a promising technology for the production of lightweight and energy-efficient automobiles. The manganese-boron steel 22MnB5 have been implemented in sheet press hardening owing to their excellent hot formability, high hardenability, and good temperability even at low cooling rates. However, press-hardened components have shown poor ductility and cracking at relatively small strains. A possible solution to this problem is a selective increase of steel sheet ductility by press hardening process design in areas where the component is required to deform plastically during crash tests. To this end, process designers require information about microstructure and mechanical properties as a function of the wide spectrum of cooling rates and sequences and austenitizing treatment conditions that can be encountered in production environments. In the present work, a Continuous Cooling Transformation (CCT) diagram with corresponding material properties of sheet steel 22MnB5 was determined for a wide spectrum of cooling rates. Heating and cooling programs were conducted in a quenching dilatometer. Motivated by the importance of residual elasticity in crash test performance, this property was measured using a micro-bending test and the results were integrated into the CCT diagrams to complement the hardness testing results. This information is essential for the process design of press hardening of sheet components with gradient material properties.

Neugebauer, R.; Schieck, F.; Rautenstrauch, A.

2011-05-01

407

Process design of press hardening with gradient material property influence  

SciTech Connect

Press hardening is currently used in the production of automotive structures that require very high strength and controlled deformation during crash tests. Press hardening can achieve significant reductions of sheet thickness at constant strength and is therefore a promising technology for the production of lightweight and energy-efficient automobiles. The manganese-boron steel 22MnB5 have been implemented in sheet press hardening owing to their excellent hot formability, high hardenability, and good temperability even at low cooling rates. However, press-hardened components have shown poor ductility and cracking at relatively small strains. A possible solution to this problem is a selective increase of steel sheet ductility by press hardening process design in areas where the component is required to deform plastically during crash tests. To this end, process designers require information about microstructure and mechanical properties as a function of the wide spectrum of cooling rates and sequences and austenitizing treatment conditions that can be encountered in production environments. In the present work, a Continuous Cooling Transformation (CCT) diagram with corresponding material properties of sheet steel 22MnB5 was determined for a wide spectrum of cooling rates. Heating and cooling programs were conducted in a quenching dilatometer. Motivated by the importance of residual elasticity in crash test performance, this property was measured using a micro-bending test and the results were integrated into the CCT diagrams to complement the hardness testing results. This information is essential for the process design of press hardening of sheet components with gradient material properties.

Neugebauer, R. [Fraunhofer Institute for Machine Tools and Forming Technology IWU, Chemnitz (Germany); Professorship for Machine Tools and Forming Technology, TU Chemnitz (Germany); Schieck, F. [Fraunhofer Institute for Machine Tools and Forming Technology IWU, Chemnitz (Germany); Rautenstrauch, A. [Professorship for Machine Tools and Forming Technology, TU Chemnitz (Germany)

2011-05-04

408

Work plan, AP-102 mixer pump removal and pump replacement  

SciTech Connect

The objective of this work plan is to plan the steps and estimate the costs required to remove the failed AP-102 mixer pump, and to plan and estimate the cost of the necessary design and specification work required to order a new, but modified, mixer pump including the pump and pump pit energy absorbing design. The main hardware required for the removal of the mixer is as follows: a flexible receiver and blast shield; a metal container for the pulled mixer pump; and a trailer and strongback to haul and manipulate the container. Additionally: a gamma scanning device will be needed to detect the radioactivity emanating from the mixer as it is pulled from the tank; a water spray system will be required to remove tank waste from the surface of the mixer as it is pulled from the AP-102 tank; and a lifting yoke to lift the mixer from the pump pit (the SY-101 Mixer Lifting Yoke will be used). A ``green house`` will have to be erected over the AP-102 pump pit and an experienced Hoisting and Rigging crew must be assembled and trained in mixer pump removal methods before the actual removal is undertaken.

Jimenez, R.F.

1994-09-01

409

Factors from Trypanosoma cruzi interacting with AP-1 sequences.  

PubMed

Interaction between factors from Trypanosoma cruzi extracts and AP-1 sequences was studied by electrophoretic mobility shift assays. Using a double-stranded probe carrying the AP-1 sequence from the SV40 promoter, three specific complexes designated A, B, and C were detected. Complexes A and C were formed when using single-stranded probes. The relative amount of complex B, specific for double-stranded DNA, increased as a function of probe length. Complexes were stabilized by cross-linking with UVC irradiation and resolved on denaturing SDS-PAGE. Complex A generated bands of 60- and 39 kDa; complex B produced two bands of 46- and 43 kDa; and complex C generated one band of 43 kDa. The AP-1 binding activity was much higher in purified nuclear preparations than in soluble fractions, and was detected in crude extracts from the three forms of the parasite. The binding signal, however, was much stronger in amastigote and trypomastigote than in the epimastigote forms. Specific binding was increased by oxidative stress. Antibodies raised against peptides corresponding to conserved domains of mammalian c-Jun and c-Fos detected bands of 40- and 60 kDa, respectively, in a nuclear epimastigote preparation. PMID:10519220

Espinosa, J; Martinetto, H; Portal, D; D'Angelo, M; Torres, H N; Flawiá, M M

1999-01-01

410

JUNB/AP-1 controls IFN-? during inflammatory liver disease  

PubMed Central

Understanding the molecular pathogenesis of inflammatory liver disease is essential to design efficient therapeutic approaches. In hepatocytes, the dimeric transcription factor c-JUN/AP-1 is a major mediator of cell survival during hepatitis, although functions for other JUN proteins in liver disease are less defined. Here, we found that JUNB was specifically expressed in human and murine immune cells during acute liver injury. We analyzed the molecular function of JUNB in experimental models of hepatitis, including administration of concanavalin A (ConA) or ?-galactosyl-ceramide, which induce liver inflammation and injury. Mice specifically lacking JUNB in hepatocytes displayed a mild increase in ConA-induced liver damage. However, targeted deletion of Junb in immune cells and hepatocytes protected against hepatitis in experimental models that involved NK/NKT cells. The absence of JUNB in immune cells decreased IFN-? expression and secretion from NK and NKT cells, leading to reduced STAT1 pathway activation. Systemic IFN-? treatment or adenovirus-based IRF1 delivery to Junb-deficient mice restored hepatotoxicity, and we demonstrate that Ifng is a direct transcriptional target of JUNB. These findings demonstrate that JUNB/AP-1 promotes cell death during acute hepatitis by regulating IFN-? production in NK and NKT cells and thus functionally antagonizes the hepatoprotective function of c-JUN/AP-1 in hepatocytes.

Thomsen, Martin K.; Bakiri, Latifa; Hasenfuss, Sebastian C.; Hamacher, Rainer; Martinez, Lola; Wagner, Erwin F.

2013-01-01

411

Alignment and commissionig of the APS beamline front ends  

SciTech Connect

Fifteen out of forty phase-one beamline front ends have been installed in the storage-ring tunnel at the 7-GeV Advanced Photon Source (APS). For the front-end installation, a four-step alignment process was designed and consists of (1) prealigning the front-end components with support tables in the preassembly area, (2) installing the components with tables in the storage-ring tunnel and aligning relative to the APS global telescope survey network, (3) confirming the alignment using a tooling laser alignment system, and (4) performing adjustments with the synchrotron-radiation beam during commissioning. The laser alignment system and the prealignment data- base have been of great importance for the expedient maintenance of front-end components. These tools are very important to a large synchrotron radiation facility such as the APS, since they make a quick alignment setup possible and minimize alignment time inside the tunnel. This paper will present the four-step alignment process, the laser alignment system, and discuss the alignment confirmation results. 6 refs., 5 figs.

Shu, D.; barraza, J.; Ramanathan, M.; Chang, J.; Kuzay, T.M.

1995-12-31

412

Margin Assessment of AP1000 Loss of Flow Transient  

SciTech Connect

The Reactor Coolant System (RCS) of the AP1000 plant consists of two circulating loops. Each loop contains two canned motor Reactor Coolant (RC) pumps that have a rotating inertia to provide RCS flow coast-down if power to the pumps is lost. Westinghouse analysis of the complete loss of flow (CLOF) accident in support of the AP1000 design certification was based on the USNRC-approved traditional methodology applied to operating plants. The RCS response during the transient was predicted using the LOFTRAN code based on a reactivity insertion curve highly skewed to the bottom of the reactor core, but the calculation of Departure from Nucleate Boiling Ratio (DNBR) was performed assuming a top-skewed axial power profile. A more realistic margin assessment can be made by using an improved method similar to Westinghouse RAVE methodology recently approved by the USNRC. The improved method uses the three-dimensional kinetic nodal code SPNOVA coupled with the reactor core thermal-hydraulic code VIPRE-W for predicting the reactor core response during the CLOF transient. The improved method significantly improves margin predictions by generating core power distributions consistent with the trip reactivity changes for the DNBR calculation. The margin assessment showed that the improved method resulted in a 19% DNBR increase as compared to the traditional method for the AP1000 CLOF transient. (authors)

Carlin, Edward L.; Hilton, Peter A.; Yixing Sung [Westinghouse Electric Company, LLC (United States)

2006-07-01

413

JUNB/AP-1 controls IFN-? during inflammatory liver disease.  

PubMed

Understanding the molecular pathogenesis of inflammatory liver disease is essential to design efficient therapeutic approaches. In hepatocytes, the dimeric transcription factor c-JUN/AP-1 is a major mediator of cell survival during hepatitis, although functions for other JUN proteins in liver disease are less defined. Here, we found that JUNB was specifically expressed in human and murine immune cells during acute liver injury. We analyzed the molecular function of JUNB in experimental models of hepatitis, including administration of concanavalin A (ConA) or ?-galactosyl-ceramide, which induce liver inflammation and injury. Mice specifically lacking JUNB in hepatocytes displayed a mild increase in ConA-induced liver damage. However, targeted deletion of Junb in immune cells and hepatocytes protected against hepatitis in experimental models that involved NK/NKT cells. The absence of JUNB in immune cells decreased IFN-? expression and secretion from NK and NKT cells, leading to reduced STAT1 pathway activation. Systemic IFN-? treatment or adenovirus-based IRF1 delivery to Junb-deficient mice restored hepatotoxicity, and we demonstrate that Ifng is a direct transcriptional target of JUNB. These findings demonstrate that JUNB/AP-1 promotes cell death during acute hepatitis by regulating IFN-? production in NK and NKT cells and thus functionally antagonizes the hepatoprotective function of c-JUN/AP-1 in hepatocytes. PMID:24200694

Thomsen, Martin K; Bakiri, Latifa; Hasenfuss, Sebastian C; Hamacher, Rainer; Martinez, Lola; Wagner, Erwin F

2013-12-01

414

Stress–strain behavior of polyamide 6 staple fibers of punch-needled press felts under simulated wet-pressing conditions  

Microsoft Academic Search

This study evaluates the specific stress (tenacity) and strain (elongation) of polyamide 6 staple fibers, which were virgin, punch-needled on the press felt, and worn on the press felt under simulated wet-pressing conditions. The staple fibers were distinguished by molecular weights. The fiber deformation and defects were microscopically characterized after the felt preparation and aging. We discovered that the tensile

Tomi Hakala; Osmo Kaleva; Ali Harlin

2012-01-01

415

Properties of Hot Pressed Titanium Alloy Powders for Cryogenic Applications.  

NASA Technical Reports Server (NTRS)

Evaluation of strength and toughness of hot-pressed titanium alloy powders at room and at cryogenic temperatures. The purpose was to determine how the mechanical properties of solid bodies formed from powder would compare with wrought specimens of the same size and with the same chemical analysis. It was found that of five titanium powder-making processes investigated, only the Rotating Electrode Process (REP) was capable of producing ELI-grade titanium alloy powder. Blocks hot-pressed from spherical REP powders had tensile properties equivalent to or better than those obtained from wrought bar.

Friedman, G. I.; Kazaroff, J. M.

1970-01-01

416

Canning Of Powdered Metal For Hot Isostatic Pressing  

NASA Technical Reports Server (NTRS)

Quality of specimen enhanced by improved canning process. Method developed for canning specimens for hot isostatic pressing. Specimen placed inside refractory-metal ring, then sandwiched between two refractory-metal face sheets. Assembly placed inside die, then positioned in vacuum hot press. Heated to set temperature at prescribed vacuum to burn off all of binder in specimen. Advantages: powder-metallurgy composite totally purged of binder sealed in can in single operation, maintains size, shape, and uniformity of specimen. Weld region does not recrystallize, and little possibility of cracking.

Juhas, John J.

1989-01-01

417

New technique of machining high precision mirror surface press roller  

NASA Astrophysics Data System (ADS)

High precision mirror surface press roller machining technique of corrosion and grinding proof is one of the key techniques that the production enterprises as well as the machining and manufacturing of the following industries sought to resolve for a long time: plastics, papermaking, rubber, film, and chip production. In Oct. 1984, a new comprehensive machining technique of metal brush coating, grinding with abrasive belt, as well as buffing was used to conduct nearly 20 experiments. In Jan. 1985, a pair of middle convex high precision mirror surface press rollers was successfully machined. The technical process is described.

Hongsen, Deng

1991-03-01

418

Follicular contact dermatitis due to coloured permanent-pressed sheets  

PubMed Central

A delayed hypersensitivity type of allergic contact dermatitis was observed following exposure to certain brands of 50% cotton, 50% polyester coloured permanent-pressed sheets produced by a particular manufacturer. The dermatitis presented as an extremely pruritic follicular eczema of the body and vesicular edema of the ears and face. Patch testing excluded formalin as the allergen but suggested permanent-pressing chemicals as a possibility. Several washings of the sheets did not prevent the development of the dermatitis. The removal of sheets did not immediately result in improvement: the condition could persist for up to eight weeks after their discontinuance. ImagesFIG. 1FIG. 2FIG. 3FIG. 4FIG. 5

Panaccio, Francois; Montgomery, D. C.; Adam, J. E.

1973-01-01

419

The mammography screening controversy: who and what is heard in the press?  

PubMed

The objective of this project was to analyze newspaper coverage of the January 2000 meta-analysis by Gotzsche and Olsen, "Is screening for breast cancer with mammography justified?" [Lancet 355 (2000) 129]. A content analysis was performed on a comprehensive set of newspaper clippings from the UK during the 2 weeks following publication of the Lancet article. The original authors were most quoted in Wave 1 (the first weekend); the screening programme was most quoted in Wave 2 (week 2). Screening programme description, and the "quality" of the Lancet article dominated Wave 1; patient testimonials increased in Wave 2. Newspaper articles were structured as debates between experts and advocates, thereby enhancing polarisation of opinion. We suggest this is counter-productive to evidence-based patient choice and public involvement in decision-making. Medical journals' and charities' press releases that begin to include discussion of uncertainty inherent in medical technologies can contribute to evidence-based public deliberation. PMID:12915283

Holmes-Rovner, Margaret; Charles, Sonya

2003-09-01

420

P686Abnormal electrical activity of remodelled T-tubules promotes asynchronous Ca2+ release in heart failure.  

PubMed

Action potential (AP), via the transverse axial tubular system (TATS), synchronously triggers uniform Ca2+-release throughout the cardiomyocyte. Cardiac diseases associated with TATS structural remodeling preclude a uniform Ca2+-release across the myocyte, contributing to contractile dysfunction. Here, we combined the advantage of an ultrafast random access multi-photon (RAMP) microscope with a double staining approach to optically record AP in several TATS elements and, simultaneously, the corresponding local Ca2+-transient. In rat control cardiomyocytes, although AP was uniform between surface sarcolemma (SS) and t-tubules (TT) at steady-state stimulation, we observed a non-negligible beat-to-beat variability of local Ca2+-transient amplitude and kinetics. This variability was significantly reduced applying 0.1 ?M Isoproterenol, which increases the open probability of Ca2+-release units. Ca2+ sparks, detected at times throughout the TATS, did not induce any membrane potential variation in the surrounding tubular elements. In a rat model of post-ischemic heart failure (HF), we previously demonstrated that some tubular elements fail to propagate AP (AP-; Sacconi PNAS 2012). Here, we found that those AP- tubules displayed a slower and reduced local Ca2+-transient compared to electrically coupled tubules (AP+). Consistently, in a model of acute detubulation, tubules that do not conduct AP showed a local reduction and delay of Ca2+-transient rise. In addition, variability of Ca2+-transient kinetics was increased in HF. Finally, AP- tubular elements, occasionally exhibited spontaneous depolarisations of various amplitude and kinetics. These events were never accompanied by local Ca2+-release in the absence of pro-arrhythmogenic stimuli, while they could induce local Ca2+-release in the presence of 0.1 ?M Isoproterenol. Simultaneous recording of AP and Ca2+-transient allows us to probe the spatio-temporal variability of Ca2+-release, whereas the investigation of Ca2+-transient in HF discloses an unexpected uncoupling between t-tubular depolarization and Ca2+-release in remodelled tubules. This work was supported by the European Union 7th Framework Program (FP7/2007- 2013) under grant agreement n° 284464, 241526, by the Italian Ministry of University and Research (NANOMAX), and by Telethon-Italy (GGP13162). PMID:25020413

Crocini, C; Coppini, R; Ferrantini, C; Yan, P; Loew, L; Tesi, C; Poggesi, C; Cerbai, E; Pavone, F S; Sacconi, L

2014-07-15

421

Clathrin assembly protein AP2 induces aggregation of membrane vesicles: a possible role for AP2 in endosome formation  

Microsoft Academic Search

We have examined the in vitro behavior of clathrin-coated vesicles that have been stripped of their surface coats such that the majority of the clathrin is removed but substantial amounts of clathrin assembly proteins (AP) remain membrane-associated. Aggre- gation of these stripped coated vesicles (s-CV) is ob- served when they are placed under conditions that approximate the pH and ionic

Kenneth A. Beck; Michael Chang; Frances M. Brodsky; James H. Keen

1992-01-01

422

Controlled release of thiram fungicide from starch-based hydrogels  

Microsoft Academic Search

In order to make the judicious use of thiram fungicide and to exploit the potential of agri-polymers, we have developed the starch- poly(acrylamide) and starch-poly(acrylic acid) based agrichemical delivery system (hydrogels) for its controlled and sustained release. Polymeric networks have been prepared by using N,N?-methylenebisacrylamide (N,N-MBAAm) as crosslinker and ammonium persulfate (APS) as initiator and characterized by Fourier transform infrared

Baljit Singh; D. K. Sharma; Atul Gupta

2007-01-01

423

Purification of recombinant nacre-associated mineralization protein AP7 fused with maltose-binding protein.  

PubMed

Formation of biominerals often involves specific proteins that modulate the process of matrix assembly, nucleation, and crystal growth. AP7 is an aragonite-associated protein of 7kDa and is intrinsically disordered. The structural disorder of AP7 makes it very difficult to express in Escherchiacoli. In this work, we report the first successful expression and purification of recombinant AP7 using the maltose-binding protein (MBP) fusion approach. We obtain a high-yield production of recombinant MBP-AP7 protein inE. coli (?60mg/L). We also establish an efficient protocol to remove the MBP fusion protein by Factor Xa, followed by purification using size-exclusion chromatography. Characterization of the recombinant AP7 protein has been carried out using MALDI-TOF, peptide mass fingerprinting, and circular dichroism (CD). The mass data confirm that the purified recombinant protein is AP7. The CD data suggest that the recombinant AP7 protein exists as partially disordered structure at neutral pH. The calcium carbonate precipitation assay shows that both MBP-AP7 and AP7 exhibit morphological modification on calcite crystallites. The co-precipitation of MBP-tagged AP7 derivatives and calcium carbonate generate different types of AP7 composite calcite and vaterite crystals. This system should be helpful to establish a model for understanding the structure/function relationship between the protein and inorganic mineral interaction. PMID:24837160

Huang, Yu-Chieh; Chang, Hsun-Hui; Mou, Yun; Chi, Peter; Chan, Jerry Chun Chung; Luo, Shih-Chi

2014-08-01

424

Hot isostatic pressing of direct selective laser sintered metal components  

Microsoft Academic Search

A new manufacturing process combining the benefits of Selective Laser Sintering (SLS) and Hot Isostatic Pressing (HIP) has been developed to permit Rapid Prototyping of high performance metal components. The new process uses Direct Metal SLS to produce a gas impermeable HIP container from the same powdered material that will eventually compose the bulk of the part. The SLS generated

Martin Steven Wohlert

2000-01-01

425

Book Review: Stars (Copyright 1985, Golden Press; New York)  

NASA Astrophysics Data System (ADS)

Stars is a part of the Golden Guides collection produced by Golden Press. It is a small 160 page paperback guide to the constellations, the sun, the moon, planets, and other celestial bodies. The book is convenient to carry along wherever you go, making it an easy to access reference material.

Marigza, R. N., Jr.

2009-06-01

426

A die pressing test for the estimation of agglomerate strength  

SciTech Connect

A die pressing test was developed for quick and inexpensive estimation of the agglomerate strength of ceramic powders. The critical nominal pressure (p[sub c]) at which contact areas between agglomerates start to increase rapidly was found from the relationship between change in sample height and applied pressure in uniaxial single-ended die pressing. A quantitative microscopic method was used for measuring the area fraction ([psi]) of agglomerates which transmits the force through the assembly. A die pressing agglomerate strength, [sigma][sub d], is defined as [sigma][sub d] = 0.7 p[sub c]/[Psi]. This strength was compared with the agglomerate tensile strength obtained from single agglomerate diametral compression tests and found to be 50% higher than the latter because of multipoint loading. A suggested guideline is that the mean agglomerate tensile strength is approximately 52% of p[sub c] determined in a die pressing test for spherical agglomerates. In addition to agglomerate tensile strength, the mean agglomerate size, the interior macropore structure of agglomerates, as well as the packing efficiencies between and inside agglomerates can be estimated by the procedure.

Song, Jia Hua; Evans, J.R.G. (Brunel Univ., Uxbridge (United Kingdom). Dept. of Materials Technology)

1994-03-01

427

SOURCE ASSESSMENT: PRESSED AND BLOWN GLASS MANUFACTURING PLANTS  

EPA Science Inventory

This report summarizes the results of a study to gather and analyze background information and technical data related to air emissions from glass manufacturers producing pressed and blown glassware. This includes all glassware except flat glass, glass containers, and fiber glass....

428

Argonne Director Eric Isaacs addresses the National Press Club  

SciTech Connect

Argonne Director Eric Isaacs addresses the National Press Club on 9/15/2009. To build a national economy based on sustainable energy, the nation must first "reignite its innovation ecology," he said. Issacs makes the case for investing in science to secure America's future.

Eric Isaccs

2009-09-17

429

Democratic Socialism: Toward a Fifth Theory of the Press.  

ERIC Educational Resources Information Center

For more than 25 years, the "four theories" paradigm has been dominant in the study of the relationships among the press, society, and the state. Asserting that the major approaches to such study are the libertarian, social responsibility, authoritarian, and Soviet/communist theories, this paradigm fails to account for economic and social…

Picard, Robert G.

430

Pressing for Elaboration in Student Talk about Texts  

ERIC Educational Resources Information Center

This article explores the practice of one accomplished teacher who uses follow-up probes to press her fourth- and fifth-grade students to clarify and articulate their ideas more fully. Qualitative analysis of field notes, teacher and student interviews, and video recordings of instruction, and discourse analysis of reading conferences revealed…

McElhone, D.

2013-01-01

431

University Press Meeting Dominated by Donor Proposal and Digital Publishing  

ERIC Educational Resources Information Center

A surprise request for proposals from the Andrew W. Mellon Foundation and a forthcoming report on university publishing in the digital age were among topics discussed at the annual meeting of the Association of American University Presses. The offer from the Mellon Foundation concerns support for collaborative, monograph-centered projects in…

Howard, Jennifer

2007-01-01

432

Freedom of Speech and Press: Exceptions to the First Amendment.  

National Technical Information Service (NTIS)

This report provides an overview of the major exceptions to the First Amendment -- of the ways that the Supreme Court has interpreted the guarantee of freedom of speech and press to provide no protection or only limited protection for some types of speech...

H. Cohen

2007-01-01

433

Quid Pro Quo: Tobacco Companies and the Black Press  

PubMed Central

Objectives. We explored the relationship between tobacco companies and the Black press, which plays an important role in conveying information and opinions to Black communities. Methods. In this archival case study, we analyzed data from internal tobacco industry documents and archives of the National Newspaper Publishers Association (NNPA), the trade association of the Black press. Results. In exchange for advertising dollars and other support, the tobacco industry expected and received support from Black newspapers for tobacco industry policy positions. Beginning in the 1990s, resistance from within the Black community and reduced advertising budgets created counterpressures. The tobacco industry, however, continued to sustain NNPA support. Conclusions. The quid pro quo between tobacco companies and the Black press violated journalistic standards and represented an unequal trade. Although numerous factors explain today's tobacco-related health disparities, the Black press's service to tobacco companies is problematic because of the trust that the community placed in such media. Understanding the relationship between the tobacco industry and the NNPA provides insight into strategies that the tobacco industry may use in other communities and countries.

McCandless, Phyra M.; Yerger, Valerie B.

2012-01-01

434

Argonne Director Eric Isaacs addresses the National Press Club  

ScienceCinema

Argonne Director Eric Isaacs addresses the National Press Club on 9/15/2009. To build a national economy based on sustainable energy, the nation must first "reignite its innovation ecology," he said. Issacs makes the case for investing in science to secure America's future.

Eric Isaccs

2010-01-08

435

A study on detonation characteristics of pressed NTO  

Microsoft Academic Search

NTO is an explosive of current interest. It has been evaluated as an insensitive component to replace RDX in some explosive and propellant compositions. In our work, efforts were made to determine NTO detonation pressure and JWL equation of state of NTO detonation products. With this end in view, pressed NTO cylinders were studied experimentally by measuring the detonation velocity

S. Cudzilo; W. A. Trzcinski

2001-01-01

436

Developing Model-Based Control Strategies for Hot Isostatic Pressing.  

National Technical Information Service (NTIS)

The objective of the project is to study the model-based feedback control of hot isostatic pressing process for the purposes of improving quality and maintaining product consistency. A control strategy in the form of feedforward and feedback is developed ...

W. Li

1994-01-01

437

The Foreign Press: A Survey of the World's Journalism.  

ERIC Educational Resources Information Center

While there is certainly an abundance of excellent material concerning the world's press today, since World War II there has been an absence of any type of systematic synthesis of this information which might be used as a text or reference book by persons interested in the broad aspects of international communication. This book is intended to…

Merrill, John C.; And Others

438

Slag grinding by roller press—major issues  

Microsoft Academic Search

The paper sums up the results of observations made during the commissioning of the roller press (RP) for slag grinding for TISCO cement project. At the time of selection of the RP technology for this project, there was not adequate experience available in regard to the process and design parameters leading to series of problems during start up and commissioning.

S. M. Mehra

1998-01-01

439

Continuous expression of slurry in a screw press  

Microsoft Academic Search

An approximate method is described for predicting the steadystate performance of a screw press for the continuous expression of a slurry, with the worm channel being modified as the path between two flat plates. Screw expression of a slurry involves two mechanisms of dewatering which, for a batch operation, can be analyzed by the variable-pressure, variable-rate theory of filtration and

M. Shirato; N. Hayashi; M. Iwata; T. Murase; Y. Ogawa

1985-01-01

440

Neural observer for the hot isostatic pressing nonlinear system  

Microsoft Academic Search

The equations describing the hot isostatic pressing (HIP'ing) system dynamics are nonlinear, complicating any controller design for the system. Further complications arise because one of the system's states, grain size, cannot be measured directly as a system output. The goal is to reconstruct or estimate the grain size. It is first necessary to show that it is possible to reconstruct

Andrew J. Newman

1992-01-01

441

Toward a Normative Theory of Freedom of the Press.  

ERIC Educational Resources Information Center

In considering the possibility of a normative theory of freedom of the press, this paper examines arguments about such freedom in the Third World and elsewhere. Some of the arguments discussed in the paper are derived from the theories of John Locke and Karl Marx; others are drawn from the concepts of divine rights, elitism, liberal democracy, and…

Jensen, Dwight Wm.

442

Composition of Cold-Pressed Bitter Orange Oil from Cuba  

Microsoft Academic Search

Commercially produced cold-pressed oil of bitter orange (Citrus aurantium L.) produced in Cuba was analyzed by GC\\/MS. Thirty components were characterized representing 98.9% of the total components detected. Limonene (86.2%) was the major constituent.

Jorge A. Pino; Aristides Rosado

2000-01-01

443

Dead-Pressing Phenomenon in an ANFO Explosive.  

National Technical Information Service (NTIS)

The dead-pressing phenomenon or pressure desensitization in ANFO as well as in other civil explosives is well-known. However, to our knowledge, the detailed study of the phenomenon in ANFO has not been carried out nor has it been reported. Therefore, such...

S. Nie J. Deng A. Persson

1991-01-01

444

Tell Us More: Reading Comprehension, Engagement, and Conceptual Press Discourse  

ERIC Educational Resources Information Center

This study examines interactions between teachers and students during reading comprehension instruction to determine how certain patterns of teacher-student talk support student comprehension achievement and reading engagement. The central focus of the study is "conceptual press discourse," a pattern of teacher response that includes requests for…

McElhone, Dot

2012-01-01

445

Ethics and the Press: Readings in Mass Media Morality.  

ERIC Educational Resources Information Center

This collection of 35 articles addresses the topic of the ethical considerations and implications involved in reporting the news. Included in this book are such articles as: "Ethics and Journalism" by John Merrill, "Quality in Mass Communications" by Wilbur Schramm, "The American Press: Some Truths About Truths" by Edward Jay Epstein, "The New…

Merrill, John C., Ed.; Barney, Ralph D., Ed.

446

42. PRESSING A SLAB OF CLAY ONTO A MOSAIC MOLD. ...  

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

42. PRESSING A SLAB OF CLAY ONTO A MOSAIC MOLD. THE MOLD, WHICH HAS A RAISED DESIGN, LEAVES AND OUTLINE IN THE SLAB, THE PIECES THUS DEFINED, ARE THEN CUT APART TO BE FIRED SEPARATELY AND REASSEMBLED. - Moravian Pottery & Tile Works, Southwest side of State Route 313 (Swamp Road), Northwest of East Court Street, Doylestown, Bucks County, PA

447

The Feasibility of Pressing Aluminum Powder in Porous Lined die.  

National Technical Information Service (NTIS)

An experimental study is made of the feasibility of cold pressing unlubricated aluminum powder in a porous lined die. Results of lubricant flow through the porous liner are given and discussed. A comparison is presented of two lubricants, butyl stearate a...

L. R. Goodwin

1970-01-01

448

Inverse piano technique for studying finger interaction during pressing tasks  

Microsoft Academic Search

When a person moves or presses with an individual finger other fingers also produce a force (Kilbreath and Gandevia 1994; Li et al. 2004; Zatsiorsky et al. 2000). Several factors are known to contribute to this response: (1) peripheral mechanical coupling, (2) multi-digit motor units, and (3) diverging central commands. This phenomenon, known as enslaving, has traditionally been studied in

Joel Martin; Mark L. Latash; Vladimir M. Zatsiorsky

2009-01-01

449

29 CFR 1910.217 - Mechanical power presses.  

Code of Federal Regulations, 2013 CFR

...required to make one press cycle is so remote as to be a negligible risk factor in the total array of equipment and human factors. The emphasis is on an integrated total system including all elements affecting point of operation safety....

2013-07-01

450

STS-32 Post-Flight Crew Press Conference  

NASA Technical Reports Server (NTRS)

Video footage of the post-flight press conference of STS-32 is presented. The footage is narrated by the crew, and it covers the following topics: launch, deployment of Syncom IV-5, retrieval of the Long Duration Exposure Facility, in-orbit activities, and the landing.

1990-01-01

451

Improving Dryer and Press Efficiencies Through Combustion of Hydrocarbon Emissions  

Microsoft Academic Search

Emission control devices on dryers and presses have been legislated into the industry, and are now an integral part of the drying system. These devices consume large quantities of natural gas and electricity and down-sizing or eliminating them will provide major energy savings. The principal strategy taken here focuses on developing process changes that should minimize (and in some cases

Sujit Banerjee

2005-01-01

452

Gemini 4 prime crew with NASA Officials after press conferences  

NASA Technical Reports Server (NTRS)

The Gemini 4 prime crew poses with two NASA Officials after a press conference in the Manned Spaceflight Center (MSC) auditorium. Left to right are Dr. Robert R. Gilruth, MSC Director; Dr. Robert C. Seamans Jr., Associate NASA Administrator; Astronaut James A. McDivitt, command pilot of the Gemini 4 flight; and Astronaut Edward H. White II, pilot of the mission.

1965-01-01

453

Structural characterization of the hemophore HasAp from Pseudomonas aeruginosa: NMR spectroscopy reveals protein-protein interactions between Holo-HasAp and hemoglobin.  

PubMed

Pseudomonas aeruginosa secretes a 205 residue long hemophore (full-length HasAp) that is subsequently cleaved at the C'-terminal domain to produce mainly a 184 residue long truncated HasAp that scavenges heme [Letoffé, S., Redeker, V., and Wandersman, C. (1998) Mol. Microbiol. 28, 1223-1234]. HasAp has been characterized by X-ray crystallography and in solution by NMR spectroscopy. The X-ray crystal structure of truncated HasAp revealed a polypeptide alphabeta fold and a ferriheme coordinated axially by His32 and Tyr75, with the side chain of His83 poised to accept a hydrogen bond from the Tyr75 phenolic acid group. NMR investigations conducted with full-length HasAp showed that the carboxyl-terminal tail (21 residues) is disordered and conformationally flexible. NMR spectroscopic investigations aimed at studying a complex between apo-HasAp and human methemoglobin were stymied by the rapid heme capture by the hemophore. In an effort to circumvent this problem NMR spectroscopy was used to monitor the titration of 15N-labeled holo-HasAp with hemoglobin. These studies allowed identification of a specific area on the surface of truncated HasAp, encompassing the axial ligand His32 loop that serves as a transient site of interaction with hemoglobin. These findings are discussed in the context of a putative encounter complex between apo-HasAp and hemoglobin that leads to efficient hemoglobin-heme capture by the hemophore. Similar experiments conducted with full-length 15N-labeled HasAp and hemoglobin revealed a transient interaction site in full-length HasAp similar to that observed in the truncated hemophore. The spectral perturbations observed while investigating these interactions, however, are weaker than those observed for the interactions between hemoglobin and truncated HasAp, suggesting that the disordered tail in the full-length HasAp must be proteolyzed in the extracellular milieu to make HasAp a more efficient hemophore. PMID:19072037

Alontaga, Aileen Y; Rodriguez, Juan Carlos; Schönbrunn, Ernst; Becker, Andreas; Funke, Todd; Yukl, Erik T; Hayashi, Takahiro; Stobaugh, Jordan; Moënne-Loccoz, Pierre; Rivera, Mario

2009-01-13

454

Structural characterization of the hemophore HasAp from Pseudomonas aeruginosa: NMR spectroscopy reveals protein-protein interactions between holo-HasAp and hemoglobin†,‡  

PubMed Central

Pseudomonas aeruginosa secretes a 205 residue long hemophore (full-length HasAp) that is subsequently cleaved at the C’-terminal domain to produce mainly a 184 residue long truncated HasAp that scavenges heme [Letoffé, S., Redeker, V., and Wandersman, C. (1998) Mol. Microbiol. 28, 1223–1234]. HasAp has been characterized by X-ray crystallography and in solution by NMR spectroscopy. The X-ray crystal structure of truncated HasAp revealed a polypeptide ?? fold and a ferriheme coordinated axially by His32 and Tyr75, with the side chain of His83 poised to accept a hydrogen bond from the Tyr75 phenolic acid group. NMR investigations conducted with full-length HasAp showed that the carboxyl terminal tail (21 residues) is disordered and conformationally flexible. NMR spectroscopic investigations aimed at studying a complex between apo-HasAp and human met-hemoglobin were stymied by the rapid heme capture by the hemophore. In an effort to circumvent this problem NMR spectroscopy was used to monitor the titration of 15N-labeled holo-HasAp with hemoglobin. These studies allowed identification of a specific area on the surface of truncated HasAp, encompassing the axial ligand His32 loop that serves as a transient site of interaction with hemoglobin. These findings are discussed in the context of a putative encounter complex between apo-HasAp and hemoglobin that leads to efficient hemoglobin-heme capture by the hemophore. Similar experiments conducted with full-length 15N-labeled HasAp and hemoglobin revealed a transient interaction site in full-length HasAp similar to that observed in the truncated hemophore. The spectral perturbations observed while investigating these interactions, however, are weaker than those observed for the interactions between hemoglobin and truncated HasAp, suggesting that the disordered tail in the full-length HasAp must be proteolyzed in the extracellular milieu to make HasAp a more efficient hemophore.

Alontaga, Aileen Y.; Rodriguez, Juan Carlos; Schonbrunn, Ernst; Becker, Andreas; Funke, Todd; Yukl, Erik T.; Hayashi, Takahiro; Stobaugh, Jordan; Moenne-Loccoz, Pierre; Rivera, Mario

2009-01-01

455

Two peptides, TsAP-1 and TsAP-2, from the venom of the Brazilian yellow scorpion, Tityus serrulatus: evaluation of their antimicrobial and anticancer activities.  

PubMed

Here we report two novel 17-mer amidated linear peptides (TsAP-1 and TsAP-2) whose structures were deduced from cDNAs cloned from a venom-derived cDNA library of the Brazilian yellow scorpion, Tityus serrulatus. Both mature peptides were structurally-characterised following their location in chromatographic fractions of venom and synthetic replicates of each were subjected to a range of biological assays. The peptides were each active against model test micro-organisms but with different potencies. TsAP-1 was of low potency against all three test organisms (MICs 120-160 ?M), whereas TsAP-2 was of high potency against the Gram-positive bacterium, Staphylococcus aureus (MIC 5 ?M) and the yeast, Candida albicans (10 ?M). Haemolytic activity of TsAP-1 was low (4% at 160 ?M) and in contrast, that of TsAP-2 was considerably higher (18% at 20 ?M). Substitution of four neutral amino acid residues with Lys residues in each peptide had dramatic effects on their antimicrobial potencies and haemolytic activities, particularly those of TsAP-1. The MICs of the enhanced cationic analogue (TsAP-S1) were 2.5 ?M for S. aureus/C. albicans and 5 ?M for E. coli but with an associated large increase in haemolytic activity (30% at 5 ?M). The same Lys residue substitutions in TsAP-2 produced a dramatic effect on its MIC for E. coli lowering this from >320 ?M to 5 ?M. TsAP-1 was ineffective against three of the five human cancer cell lines tested while TsAP-2 inhibited the growth of all five. Lys residue substitution of both peptides enhanced their potency against all five cell lines with TsAp-S2 being the most potent with IC50 values ranging between 0.83 and 2.0 ?M. TsAP-1 and TsAP-2 are novel scorpion venom peptides with broad spectrum antimicrobial and anticancer cell activities the potencies of which can be significantly enhanced by increasing their cationicity. PMID:23770440

Guo, Xiaoxiao; Ma, Chengbang; Du, Qiang; Wei, Ran; Wang, Lei; Zhou, Mei; Chen, Tianbao; Shaw, Chris

2013-09-01

456

Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo.  

PubMed Central

Phorbol esters stimulate and glucocorticoid hormones down-regulate a variety of promoters such as that of the collagenase gene through the transcription factor AP-1 (Fos/Jun). We now show by genomic footprinting of the collagenase promoter that phorbol ester treatment of cells results in the binding of AP-1 to its cognate DNA binding site in vivo. The DNA-protein contacts obtained in living cells are also found in vitro using cloned DNA and purified AP-1. Although in vitro synthesized glucocorticoid receptor can disturb the DNA binding of Jun homodimers, it does not interfere with the binding of Fos-Jun heterodimers or of purified AP-1 in vitro. Consistently, fully inhibitory doses of glucocorticoid hormone cause no change in apparent occupation of the AP-1 binding site in vivo. The hormone receptor acts without itself binding to DNA. Images

Konig, H; Ponta, H; Rahmsdorf, H J; Herrlich, P

1992-01-01

457

Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo.  

PubMed

Phorbol esters stimulate and glucocorticoid hormones down-regulate a variety of promoters such as that of the collagenase gene through the transcription factor AP-1 (Fos/Jun). We now show by genomic footprinting of the collagenase promoter that phorbol ester treatment of cells results in the binding of AP-1 to its cognate DNA binding site in vivo. The DNA-protein contacts obtained in living cells are also found in vitro using cloned DNA and purified AP-1. Although in vitro synthesized glucocorticoid receptor can disturb the DNA binding of Jun homodimers, it does not interfere with the binding of Fos-Jun heterodimers or of purified AP-1 in vitro. Consistently, fully inhibitory doses of glucocorticoid hormone cause no change in apparent occupation of the AP-1 binding site in vivo. The hormone receptor acts without itself binding to DNA. PMID:1318196

König, H; Ponta, H; Rahmsdorf, H J; Herrlich, P

1992-06-01

458

The surface chemistry of the magnetic Ap star HD 147010  

NASA Astrophysics Data System (ADS)

HD 147010 is a hot (Teff = 13 000 K), large-field magnetic Ap star that is a member of the Upper Scorpius-Centaurus Association, which means it is a star with a well-defined age (log t = 6.70). We offer a comprehensive analysis of the magnetic field and surface chemistry of HD 147010 based on seven spectra obtained using CFHT's ESPaDOnS spectropolarimeter. This data set is sufficient to obtain a first-order model of the magnetic field and obtain the abundance distribution of He, O, Mg, Al, Si, Ca, Ti, Cr, Fe, Ni, Sr, La, Ce, Pr, Nd and Sm. The magnetic field model is a low-order multipole expansion based on the variations of the line of sight and surface magnetic fields with rotation. Spectral synthesis was carried out using ZEEMAN, a program which takes into account the influence of the magnetic field. A simple model of uniform abundance in each of two rings in the observed magnetic hemisphere with equal spans in colatitude was used. The new magnetic field measurements enabled us to re-analyse the rotation period of HD 147010, finding P = 3.9207 ± 0.0003 d. The line of sight and surface magnetic field strengths vary from about -2000 to -5000 G and 11000 to 17000 G, respectively. Our analysis finds large overabundances of Fe-peak and rare-earth elements relative to the solar ratios. In all cases, where strong variability in surface chemistry is observed, abundances are higher near the magnetic equator as compared to the magnetic pole. HD 147010 appears to be an Ap star that is highly rich in rare-earth elements that are of the order of 105 times more abundant than in the Sun. This analysis adds to the growing number of hot Ap stars for which both the magnetic field and abundance distribution have been studied in detail.

Bailey, J. D.; Landstreet, J. D.

2013-06-01

459

Abundance analysis of roAp stars. II. HD 203932  

NASA Astrophysics Data System (ADS)

A new tool to simplify abundance analyses which is based on stand-alone programs has been applied to the rapidly oscillating Ap star HD 203932 (BI Mic, CD -30 18600, SAO 212996; Ap(SrEu), V=8.82mag). The spectroscopically determined T_eff_=7450+/-100K and logg=4.3+/-0.15 put this star close to the ZAMS. Other fundamental atmospheric parameters are v_micro_<0.6km/s and the total abundance of all iron peak elements [M/H]=0.0+/-0.1. The fundamental parameters put HD 203932 in a region of the HR-diagram where convection starts becoming efficient and the standard mixing length theory models lead to severe problems in the determination of the atmospheric parameters. The difference between the upper limit for logg obtained from several variants of the mixing length theory and the Canuto-Mazzitelli model indicates that the choice of a particular convection model can influence the determination of basic stellar parameters. For the first time abundances were determined for HD 203932 showing a pattern for the 35 investigated elements which is similar to ? Cir (Kupka et al. 1996A&A...308..886K, Paper I). Fe and Ni have about solar abundance, Cr and especially Co are clearly overabundant as well as rare earth elements. The most underabundant element is Sc, followed by C, N, and O, which is a common property of CP2 stars. The lack of a correlation in our data between individual line abundances and their effective Lande factors implies a mean magnetic field modulus not exceeding few kG. Compared to the last homogeneous spectroscopic investigation of a large sample of chemically peculiar stars (21 cool Ap stars, Adelman 1973ApJ...183...95A), our analysis is based on data with higher spectral resolution and signal-to-noise ratio. Even more important, we are using a much larger atomic line data base with more precise atomic parameters than available more than twenty years ago.

Gelbmann, M.; Kupka, F.; Weiss, W. W.; Mathys, G.

1997-03-01

460

Effects of AP particle size on combustion response to crossflow  

NASA Technical Reports Server (NTRS)

An analytical model is developed for the linearized velocity-coupled combustion response function. The model treats elements of response to perturbations in pressure, in composition due to the heterogeneity of composite propellants, and in crossflow velocity. The effects of AP particle size are accounted for in terms of effects on controlling ballistics properties and in terms of fluctuations in propellant composition. There are two facets of the crossflow problem: the effect of crossflow velocity on the various response elements, and the response to velocity perturbations. Both are dealt with in this paper. Important trends derived from series of parametric computations are described.

Cohen, N. S.; Strand, L. D.

1983-01-01

461

Ramp tuning of the APS booster synchrotron magnet power supplies  

SciTech Connect

The acceleration cycle of the Advanced Photon Source (APS) booster synchrotron is completed within 250 Ms and is repeated at 2 Hz. The currents in the quadrupole and sextupole magnets must track the dipole current to within tight tolerances if the beam is to remain stable during acceleration. In order to meet the performance specifications, a monitoring system, online with the main control system, is used to measure machine performance and adapt power supply reference waveforms from cycle to cycle. The system optimizes the tracking between the power supplies, thus minimizing transient effects and taking care of any slow drifts. Tuning algorithms are described and their performance evaluated. Practical considerations are also discussed.

Milton, S.V.; Carwardine, J.A.

1995-07-01

462

The NuStart AP1000 Compact Control Room Implementation  

SciTech Connect

The nuclear power industry in the United States is experiencing renewed optimism that new nuclear power plants may be constructed in the foreseeable future. Presently a number of utilities in the U.S. are considering new nuclear plant construction. Among the reasons supporting the industry's optimism is the formation of the NuStart Energy Consortium. This consortium of leading energy companies, including Westinghouse Electric Company, is working with the U.S. Department of Energy to demonstrate and test the new licensing process for obtaining a Combined Construction and Operating License (COL) for an advanced light water reactor (ALWR). One ALWR design for which the NuStart Energy Consortium is pursuing a COL application is Westinghouse's passive AP1000. AP1000 received its Final Design Approval from the USNRC in the Fall of 2004 and was granted Design Certification by the NRC on December 30, 2005. A key element of the AP1000 COL application will be to close out Design Certification COL items related to the Main Control Room (MCR) and Human System Interface (HSI) design. During the AP1000 design certification licensing efforts, a control room and HSI design process was submitted and approved. Realizing that Instrumentation and Control (I and C) and HSI technology changes rapidly, Westinghouse chose to defer the detailed design of the control room and operator interfaces. This allows the latest technology to be used when a plant is actually going to be built. To fulfill the COL items for the upcoming application Westinghouse is performing a comprehensive Human Factors Engineering program in conjunction with development of an advanced set of HSI resources for a compact control room. This paper will discuss human factors program elements completed to date and the efforts currently in progress to complete the remaining elements. It will also describe the design progress for each HSI resource including a Wall Panel Information System, computerized procedure system, advanced alarm system and universal soft controls implemented as part of a distributed control system display set. Finally the paper will also discuss Westinghouse activities in cooperation with the Nuclear Energy Institute to define the expectations for a COL application in the HFE discipline corresponding to Chapter 18 of the Standard Review Plan. (authors)

Harmon, Daryl [Westinghouse Electric Company, Windsor, CT. (United States)

2006-07-01

463

High heat-load absorbers for the APS storage ring  

SciTech Connect

The power density of the dipole x-rays in the 7-GeV APS storage ring is 261 watts/mrad at 300 mA of beam current. An array of absorbers is used in the ring to shield its vacuum chambers and diagnostics components in the path of these intense x-rays. This paper describes some of the unique absorber designs that were developed to handle the requirements of high power density and UHV compatibility with no water-to-vacuum joints.

Sharma, S.; Rotela, E.; Barcikowski, A.

2000-07-21

464

H-beta line variability in magnetic Ap stars. I  

NASA Technical Reports Server (NTRS)

Preliminary results of photometric measurements of H-beta in several Ap stars are presented. Periodic variations are found certainly in Theta Aur and Alpha (2) CVn, and possibly in Phi Dra. For the other stars upper limits for variations of H-beta are determined. Observed amplitudes are transformed into variations of equivalent width assuming specific profile variations. The results show that variations of equivalent width of H-beta in the stars investigated are of the order of 10 percent or less.

Madej, J.; Jahn, K.; Stepien, K.

1984-01-01

465

24 APS STEP-UP Fellows Present Research at NIH  

NSDL National Science Digital Library

This article is on page 174-175 of The Physiologist, October 2012. The 24 APS NIDDK STEP-UP Fellows recently finished their eight-12-week laboratory research experience and traveled to Bethesda, MD to participate in the STEP-UP Research Symposium held at the DoubleTree Bethesda Hotel and at NIH. They were joined by the other 62 NIDDK STEP-UP fellows from the other four Coordinating Centers (ChildrenÃÂs Hospital, Los Angeles; Pennsylvania State Univ.; Univ. of Maryland,Baltimore County; and Virginia Commonwealth Univ.).

APS Education Office (American Physiological Society Education Office)

2012-10-01

466

Higher-order modes in the APS storage ring waveguides  

SciTech Connect

Twelve higher-order modes (HOMs) in the single-cell accelerating cavities for the Advanced Photon Source (APS) storage ring were calculated to have complex impedances that will cause coupled-bunched instabilities near or below the 300mA positron current which is the design goal. Some of these modes couple, through the coupling loop, from the storage ring cavity into the waveguide. This study investigates the transmission of these modes from the cavity into the waveguide. The standing wave ratio (VSWR) of a WR2300 hybrid waveguide component has been measured at each HOM frequency, and its effect on the transmitted modes in the waveguide is studied.

Brauer, S.O.; Kustom, R.L.

1993-07-01

467

Operation of the APS photoinjector drive laser system.  

SciTech Connect

The APS photoinjector drive laser system has been in operation since 1999 and is achieving a performance level exceeding the requirement of stable operation of the LEUTL FEL system. One remarkable number is the UV energy stability of better than 2% rms, sometimes less than 1% rms. This report summarizes the operation experience of the laser system and the improvements made along the way. We also outline the route of upgrade of the system and some frontier laser research and development opportunities in ultrabright electron beam generation.

Li, Y.; Accelerator Systems Division (APS)

2008-08-04

468

Initial diagnostics commissioning results for the Advanced Photon Source (APS)  

SciTech Connect

Principal diagnostics systems have been installed and nearly all have been commissioned on the subsystems of the Advanced Photon Source (APS) facility. Data have been obtained on beam position, beam profile, current, beam loss rate, and synchrotron radiation monitors on both injector rings and most recently the main 7-GeV storage ring. Results for the 150- to 450-MeV electron beams in the accumulator ring, up to 7 GeV in the injector synchrotron, and 4.5 to 7 GeV in the SR will be presented.

Lumpkin, A.; Patterson, D.; Wang, X. [and others

1995-07-01

469

COMMIX analysis of AP-600 Passive Containment Cooling System  

SciTech Connect

COMMIX modeling and basic concepts that relate components, i.e., containment, water film cooling, and natural draft air flow systems. of the AP-600 Passive Containment Cooling System are discussed. The critical safety issues during a postulated accident have been identified as (1) maintaining the liquid film outside the steel containment vessel, (2) ensuring the natural convection in the air annulus. and (3) quantifying both heat and mass transfer accurately for the system. The lack of appropriate heat and mass transfer models in the present analysis is addressed. and additional assessment and validation of the proposed models is proposed.

Chang, J.F.C.; Chien, T.H.; Ding, J.; Sun, J.G.; Sha, W.T.

1992-01-01

470

COMMIX analysis of AP-600 Passive Containment Cooling System  

SciTech Connect

COMMIX modeling and basic concepts that relate components, i.e., containment, water film cooling, and natural draft air flow systems. of the AP-600 Passive Containment Cooling System are discussed. The critical safety issues during a postulated accident have been identified as (1) maintaining the liquid film outside the steel containment vessel, (2) ensuring the natural convection in the air annulus. and (3) quantifying both heat and mass transfer accurately for the system. The lack of appropriate heat and mass transfer models in the present analysis is addressed. and additional assessment and validation of the proposed models is proposed.

Chang, J.F.C.; Chien, T.H.; Ding, J.; Sun, J.G.; Sha, W.T.

1992-11-01

471

RAD51AP2, a novel vertebrate- and meiotic-specific protein, sharesa conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51  

SciTech Connect

Many interacting proteins regulate and/or assist the activities of RAD51, a recombinase which plays a critical role in both DNA repair and meiotic recombination. Yeast two-hybrid screening of a human testis cDNA library revealed a new protein, RAD51AP2 (RAD51 Associated Protein 2), that interacts strongly with RAD51. A full-length cDNA clone predicts a novel vertebrate specific protein of 1159 residues, and the RAD51AP2 transcript was observed only in meiotic tissue (i.e. adult testis and fetal ovary), suggesting a meiotic-specific function for RAD51AP2. In HEK293 cells the interaction of RAD51 with an ectopically-expressed recombinant large fragment of RAD51AP2 requires the C-terminal 57 residues of RAD51AP2. This RAD51-binding region shows 81% homology to the C-terminus of RAD51AP1/PIR51, an otherwise totally unrelated RAD51-binding partner that is ubiquitously expressed. Analyses using truncations and point mutations in both RAD51AP1 and RAD51AP2 demonstrate that these proteins use the same structural motif for RAD51 binding. RAD54 shares some homology with this RAD51-binding motif, but this homologous region plays only an accessory role to the adjacent main RAD51-interacting region, which has been narrowed here to 40 amino acids. A novel protein, RAD51AP2, has been discovered that interacts with RAD51 through a C-terminal motif also present in RAD51AP1.

Kovalenko, Oleg V.; Wiese, Claudia; Schild, David

2006-07-25

472

High Pressure Research in the Large-Volume Press at the Advanced Photon Source  

NASA Astrophysics Data System (ADS)

We present an overview of current status of high-pressure research using large-volume presses (LVP) at both GSECARS (Sector 13) and HPCAT (Sector 16) at the third-generation synchrotron facility of the Advanced Photon Source (APS), Argonne National Laboratory. These combined facilities provide a wide range of research capabilities for the high pressure community. The 230 ton Paris-Edinburgh device (jointly developed by HPCAT and GSECARS, with partial support from COMPRES) at the bending magnet (BM) beamline 16-BM-B has been used primarily for studies on liquids and glasses. We use the multi-angle energy-dispersive diffraction technique to probe structures of non-crystalline materials, and ultrasonic and falling sphere techniques to measure elasticity and viscosity of these materials. These capabilities allow us to examine the close link between structure and physical properties of non-crystalline metarials. The 1000 ton system at the insertion device (ID) beamline 13-ID-D is used extensively for acoustic velocity measurement for solids and melts. The newly developed DDIA-30 module, when used in a double-stage apparatus with sintered diamond anvils, can generate pressures in excess of 40 GPa routinely. DDIA-30 can also be used as a deformation device for larger samples or higher pressure experiments. The 250 ton system at beamline 13-BM-D as just been upgraded and can accommodate a variety of LVP techniques. Among them the D-DIA and the high-pressure x-ray tomography microscope (HPXTM) are at high demand. The D-DIA has been used for deformation at mantle conditions in both ductile and brittle regime, with acoustic emission detection. The HPXTM has been used to study volumetric properties of glasses and melts as well as 3D microstructure imaging under pressure. Latest scientific results will be highlighted.

Wang, Y.; Shen, G.

2013-05-01

473

Silencing the ap65 gene reduces adherence to vaginal epithelial cells by Trichomonas vaginalis.  

PubMed

Host parasitism by Trichomonas vaginalis is complex and in part mediated by adherence to vaginal epithelial cells (VECs). Four trichomonad surface proteins bind VECs as adhesins, and AP65 is a major adhesin with sequence identity to an enzyme of the hydrogenosome organelle that is involved in energy generation. In order to perform genetic analysis and assess the role of AP65 in T. vaginalis adherence, we silenced expression of ap65 using antisense RNA. The gene for ap65 was inserted into the vector pBS-neo in sense and antisense orientations to generate plasmids pBS-neoS (S) and pBS-neoAS (AS), respectively. Trichomonads were then transfected with S and AS plasmids for selection of stable transfectants using Geneticin, and the presence of plasmid in transfectants was confirmed by polymerase chain reaction of the neo gene. Reverse transcription polymerase chain reaction and Northern blot analysis showed decreased amounts of ap65 transcript in AS transfected parasites. Growth kinetics of the antisense-transfected and wild type organisms were similar, suggesting that silencing AP65 did not affect overall energy generation for growth. Immunoblot analysis using monoclonal antibody (mAb) to AP65 of AS transfectants showed decreased amounts of AP65 when compared to wild type or S transfectants. Not unexpectedly, this corresponded to decreased amounts of AP65 bound to VECs in a functional ligand assay. Reduction in parasite surface expression of AP65 was related to lower levels of adherence to VECs by AS-transfectants compared to control organisms. Antisense silencing of ap65 was not alleviated by growth of trichomonads in high iron, which up-regulates transcription of ap65. Our work reaffirms the role for AP65 as an adhesin, and in addition, we demonstrate antisense RNA gene silencing in T. vaginalis to study the contribution of specific genes in pathogenesis. PMID:15306014

Mundodi, V; Kucknoor, A S; Klumpp, D J; Chang, T-H; Alderete, J F

2004-08-01

474

Overexpression of the transcription factor AP37 in rice improves grain yield under drought conditions.  

PubMed

Transcription factors with an APETELA2 (AP2) domain have been implicated in various cellular processes involved in plant development and stress responses. Of the 139 AP2 genes predicted in rice (Oryza sativa), we identified 42 genes in our current study that are induced by one or more stress conditions, including drought, high salinity, low temperature, and abscisic acid. Phylogenic analysis of these 42 stress-inducible AP2 genes revealed the presence of six subgroups (I-VI) with distinct signature motifs. Two genes, AP37 and AP59, representing subgroups I and II, respectively, were functionally characterized. Both genes were found to be induced upon 2 h of exposure to drought and high-salinity conditions but to differ in their expression profile upon exposure to low temperature and abscisic acid. The overexpression of AP37 and AP59 in rice under the control of the constitutive promoter OsCc1 increased the tolerance to drought and high salinity at the vegetative stage. Increased tolerance to low temperatures was observed only in OsCc1:AP37 plants. More importantly, the OsCc1:AP37 plants showed significantly enhanced drought tolerance in the field, which increased grain yield by 16% to 57% over controls under severe drought conditions, yet exhibited no significant difference under normal growth conditions. In contrast, grain yield in OsCc1:AP59 plants in the field was reduced by 23% to 43% compared with controls under both normal and drought stress conditions. Microarray experiments identified 10 and 38 genes that are up-regulated by AP37 and AP59, respectively, in addition to 37 genes that are commonly induced by both factors. Our results suggest that the AP37 gene has the potential to improve drought tolerance in rice without causing undesirable growth phenotypes. PMID:19429605

Oh, Se-Jun; Kim, Youn Shic; Kwon, Chang-Woo; Park, Hye Kyong; Jeong, Jin Seo; Kim, Ju-Kon

2009-07-01

475

AP?4 predicts poor prognosis in non?small cell lung cancer.  

PubMed

The basic helix?loop?helix transcription factor activating enhancer?binding protein (AP)?4 has been found to be involved in tumor biology. However, the role of AP?4 in non?small cell lung cancer (NSCLC) has yet to be elucidated. The present study aimed to investigate the role of AP?4 expression in NSCLC. AP?4 expression as analyzed using quantitative polymerase chain reaction and western blot analyses of 42 fresh NSCLC samples and matched adjacent noncancerous tissues. Immunohistochemistry was performed to assess the clinical significance of AP?4 expression in tumor tissues of NSCLC patients (n=240) and matched adjacent noncancerous tissues. The correlation between AP?4 expression, clinicopathological features and clinical outcome were investigated. AP?4 expression was found to be increased in the NSCLC samples at the gene and protein levels compared with the matched adjacent noncancerous tissues. Immunohistochemistry revealed that the positive expression rates of AP?4 in the 240 NSCLC samples and the matched adjacent noncancerous tissues were 48.3 and 5.8%, respectively. Positive AP?4 expression was found to be significantly associated with the tumor, nodes and metastasis stage and nodal status. Furthermore, patients with NSCLC tumors expressing AP?4 were observed to have a poorer prognosis than those without AP?4 expression. Multivariate analysis revealed that AP?4 expression was an independent prognostic marker (hazard ratio, 2.543; 95% confidence interval, 1.18?5.016; P=0.016) in NSCLC. Thus, positive AP?4 expression may be a potential prognostic marker for NSCLC. PMID:24804973

Gong, Hai; Han, Shaorong; Yao, Hui; Zhao, Hui; Wang, Yanming

2014-07-01

476

Antisense RNA decreases AP33 gene expression and cytoadherence by T. vaginalis  

PubMed Central

Background Host parasitism by Trichomonas vaginalis is complex. Adherence to vaginal epithelial cells (VECs) is mediated by surface proteins. We showed before that antisense down-regulation of expression of adhesin AP65 decreased amounts of protein, which lowered levels of T. vaginalis adherence to VECs. We now perform antisense down-regulation of expression of the ap33 gene to evaluate and confirm a role for AP33 in adherence by T. vaginalis. We also used an established transfection system for heterologous expression of AP33 in T. foetus as an additional confirmatory approach. Results We successfully select stable trichomonads with sense (S) and antisense (AS) plasmids. RT-PCR confirmed decreased amounts of ap33 mRNA in AS-transfected parasites, and decreased amounts of AP33 had no effect on growth and viability when compared to wild-type (wt) trichomonads. Immunoblots of proteins from AS-transfectants gave significant decreased amounts of functional AP33 capable of binding to host cells compared to wt- and S-transfected trichomonads. As expected, AS-transfectants had lower levels of adherence to VECs, which was related to reduction in surface expression of AP33. Stable expression of T. vaginalis AP33::HA fusion in T. foetus was confirmed by immunoblots and fluorescence. The episomally-expressed surface AP33::HA fusion increased adherence of trichomonads to human VECs, which was abrogated with anti-AP33 serum. Conclusion These results using both antisense inhibition of gene expression and AP33 synthesis and the heterologous expression of AP33 in T. foetus confirms a role for this protein as an adhesin in T. vaginalis.

Mundodi, V; Kucknoor, AS; Alderete, JF

2007-01-01

477

Position servo control of the slider in double toggle mechanical press using Bezier curve model and fuzzy control  

Microsoft Academic Search

? Abstract—Servo press is more flexible for forming process than conventional press. The position control of the slider is the key technique in the servo presses. In order to achieve an excellent position control performance of the slider, a position servo control strategy of the slider in a servo press ? double toggle mechanical press is proposed in this paper.

Jia Xie; Shengdun Zhao; Zhenghui Sha; Jintao Liang

2011-01-01

478

APS Archive Collaborative: Building Tools for Library Partnerships  

NSDL National Science Digital Library

This is a poster from the 2008 NSDL annual meeting held in Washington, DC from September 30-October 2, 2008. The American Physiological Society (APS) Archive of Teaching Resources launched in April 2002 as a venue for colleague-to-colleague sharing. Since then, the Archive has grown into a collaborative digital library with resources catalogued by APS and three partners (HAPS, SDB, and NAHSEP). All partners used a common set of review and cataloging tools. In 2008, the Archive is being redesigned with new features for partner customization, expanded partnerships, and easier user access. New administration features allow partners to customize and handle their own submissions and reviews, including automatic email notifications. New submission features include partner-specific disciplines, keywords, special fields, and customized pages. New review features include partner-specific review criteria and forms. New search functions allow database searching via keyword (all text fields and vocabulary lists), advanced search (specific partner libraries and specific vocabularies), and browse (by disciplines, learning resource type and grade level). The personalized ÃÂMy ArchiveÃÂ retains previous functions (saving searches, saving resources to folders, sharing of folders) while also providing a listing of usersÃÂ submissions and allowing users to track submissions through the review process. The new Archive will be open to Google searches; Login for the system will be required only for submissions and ÃÂMy ArchiveÃÂ features.

PhD Marsha L Matyas (American Physiological Society Education); Amy Feuerstein (The American Physiological Society Education); Yang Yang (The American Physiological Society Education)

2009-09-29

479

Large break LOCA calculations for the AP600 design  

SciTech Connect

This paper presents the application of RELAP5 to the calculation of a Large Break (200% doubled-ended rupture) Loss-of-Colant-Accident (LBLOCA) at the reactor vessel inlet for the proposed Westinghouse AP600 design. A parametric calculation was also performed to determine effects of loss of a complete Emergency Core Cooling system (ECCS) train. These calculations were performed over the core blowdown, refill, and reflood phases of the LBLOCA and did not address long term cooling. RELAP5 was shown to be adequate for system response calculation over the period of interest. The passive safety systems were predicted to effectively mitigate the consequences of LBLOCAs; the calculations showed less severe thermal responses than for a current generation Pressurized Water Reactor (PWR) plant. The two primary differences between the AP600 design and a current generation plant that affect LBLOCA response are the lower core thermal power, which results in lower temperatures during the blowdown phase, and the long duration accumulator injection, which provides ample core inventory makeup for final quenching.

Fisher, J.E.

1992-08-01

480

Large break LOCA calculations for the AP600 design  

SciTech Connect

This paper presents the application of RELAP5 to the calculation of a Large Break (200% doubled-ended rupture) Loss-of-Colant-Accident (LBLOCA) at the reactor vessel inlet for the proposed Westinghouse AP600 design. A parametric calculation was also performed to determine effects of loss of a complete Emergency Core Cooling system (ECCS) train. These calculations were performed over the core blowdown, refill, and reflood phases of the LBLOCA and did not address long term cooling. RELAP5 was shown to be adequate for system response calculation over the period of interest. The passive safety systems were predicted to effectively mitigate the consequences of LBLOCAs; the calculations showed less severe thermal responses than for a current generation Pressurized Water Reactor (PWR) plant. The two primary differences between the AP600 design and a current generation plant that affect LBLOCA response are the lower core thermal power, which results in lower temperatures during the blowdown phase, and the long duration accumulator injection, which provides ample core inventory makeup for final quenching.

Fisher, J.E.

1992-01-01

481

Luteolin, a flavonoid, inhibits AP-1 activation by basophils  

SciTech Connect

Flavonoids including luteolin, apigenin, and fisetin are inhibitors of IL-4 synthesis and CD40 ligand expression by basophils. This study was done to search for compounds with greater inhibitory activity of IL-4 expression and to clarify the molecular mechanisms through which flavonoids inhibit their expression. Of the 37 flavonoids and related compounds examined, ayanin, luteolin, and apigenin were the strongest inhibitors of IL-4 production by purified basophils in response to anti-IgE antibody plus IL-3. Luteolin did not suppress Syk or Lyn phosphorylation in basophils, nor did suppress p54/46 SAPK/JNK, p38 MAPK, and p44/42 MAPK activation by a basophilic cell line, KU812 cells, stimulated with A23187 and PMA. However, luteolin did inhibit phosphorylation of c-Jun and DNA binding activity of AP-1 in nuclear lysates from stimulated KU812 cells. These results provide a fundamental structure of flavonoids for IL-4 inhibition and demonstrate a novel action of flavonoids that suppresses the activation of AP-1.

Hirano, Toru [Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Medical School, Osaka 565-0871 (Japan); Higa, Shinji [Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Medical School, Osaka 565-0871 (Japan); Arimitsu, Junsuke [Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Medical School, Osaka 565-0871 (Japan); Naka, Tetsuji [Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Medical School, Osaka 565-0871 (Japan); Ogata, Atsushi [Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Medical School, Osaka 565-0871 (Japan); Shima, Yoshihito [Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Medical School, Osaka 565-0871 (Japan); Fujimoto, Minoru [Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Medical School, Osaka 565-0871 (Japan); Yamadori, Tomoki [Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Medical School, Osaka 565-0871 (Japan); Ohkawara, Tomoharu; Kuwabara, Yusuke; Kawai, Mari [Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Medical School, Osaka 565-0871 (Japan); Matsuda, Hisashi; Yoshikawa, Masayuki [Kyoto Pharmaceutical University, Kyoto 607-8412 (Japan); Maezaki, Naoyoshi; Tanaka, Tetsuaki [Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871 (Japan); Kawase, Ichiro [Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Medical School, Osaka 565-0871 (Japan); Tanaka, Toshio [Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Medical School, Osaka 565-0871 (Japan)]. E-mail: ttanak@imed3.med.osaka-u.ac.jp

2006-02-03

482

Developing a Dedicated GISAXS Beamline at the APS  

NASA Astrophysics Data System (ADS)

As an increasingly important structural-characterization technique, grazing-incidence small-angle scattering (GISAXS) finds vast applications in nanostructures and nanocomposites at surfaces and interfaces for in situ and real-time studies because of its probing q-range (10-3 - 1 nm-1) and temporal resolution (10-3 - 1 s). At the Advanced Photon Source (APS), GISAXS techniques under thin-film waveguide-based resonance conditions were developed to study the diffusion phenomena in nanoparticle/polymer nanocomposites. Also, the kinematics of nanoparticle crystal formation at air/liquid interfaces has been obtained by the similar method in real time during the liquid droplet evaporation. To meet the strong demand from the nanoscience community, a dedicated GISAXS beamline has been designed and constructed as a part of the 8-ID-E beamline at the APS. This dedicated GISAXS setup was developed based on a 4-circle diffractometer so that precise reflectivity of the sample can be measured to complement the GISAXS analysis under the dynamical refection conditions.

Li, Xuefa; Narayanan, Suresh; Sprung, Michael; Sandy, Alec; Lee, Dong Ryeol; Wang, Jin

2007-01-01

483

Berberine Targets AP-2/hTERT, NF-?B/COX-2, HIF-1?/VEGF and Cytochrome-c/Caspase Signaling to Suppress Human Cancer Cell Growth.  

PubMed

Berberine (BBR), an isoquinoline derivative alkaloid isolated from Chinese herbs, has a long history of uses for the treatment of multiple diseases, including cancers. However, the precise mechanisms of actions of BBR in human lung cancer cells remain unclear. In this study, we investigated the molecular mechanisms by which BBR inhibits cell growth in human non-small-cell lung cancer (NSCLC) cells. Treatment with BBR promoted cell morphology change, inhibited cell migration, proliferation and colony formation, and induced cell apoptosis. Further molecular mechanism study showed that BBR simultaneously targeted multiple cell signaling pathways to inhibit NSCLC cell growth. Treatment with BBR inhibited AP-2? and AP-2? expression and abrogated their binding on hTERT promoters, thereby inhibiting hTERT expression. Knockdown of AP-2? and AP-2? by siRNA considerably augmented the BBR-mediated inhibition of cell growth. BBR also suppressed the nuclear translocation of p50/p65 NF-?B proteins and their binding to COX-2 promoter, causing inhibition of COX-2. BBR also downregulated HIF-1? and VEGF expression and inhibited Akt and ERK phosphorylation. Knockdown of HIF-1? by siRNA considerably augmented the BBR-mediated inhibition of cell growth. Moreover, BBR treatment triggered cytochrome-c release from mitochondrial inter-membrane space into cytosol, promoted cleavage of caspase and PARP, and affected expression of BAX and Bcl-2, thereby activating apoptotic pathway. Taken together, these results demonstrated that BBR inhibited NSCLC cell growth by simultaneously targeting AP-2/hTERT, NF-?B/COX-2, HIF-1?/VEGF, PI3K/AKT, Raf/MEK/ERK and cytochrome-c/caspase signaling pathways. Our findings provide new insights into understanding the ant